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1

Impaction of First Permanent Molars-Case Report.  

Occasionally, the extraction of an impacted tooth provides a clinical challenge for an oral surgeon. Any tooth may be impacted, but third molars and maxillary cuspids are most frequently encountered followed by premolars and supernumerary teeth. Various s...

2

Tooth separation: A risk-free procedure?  

This article reports the case of a 12-year-old patient with tooth extrusion, pain, gingival bleeding, and localized periodontitis near the maxillary second premolar. Despite probing and radiographic examination, it was not possible to establish the etiology. Tooth extraction was indicated because of the severe tooth mobility and extrusion. Curettage of the tooth socket revealed a rubber separator. Preventive approaches are suggested to avoid iatrogenesis and legal problems.

3

Effects of early tooth loss on the hippocampus in senescence-accelerated mice  

We evaluated whether long-term tooth loss induces functional and morphologic changes in the hippocampus in senescence-accelerated mice (SAMP8) maintained until old age after tooth extraction shortly after tooth eruption. First, to examine whether early tooth loss acts as a stressor, plasma concentration was measured as an index of stress. Plasma corticosterone concentration was significantly higher in old or mature mice with tooth extraction than in the age-matched controls. Plasma corticosterone concentration did not differ between the young tooth extraction and their age-matched control groups. Next, hippocampal function was assessed by evaluating spatial memory performance in the Morris water maze. In the Morris water maze learning and memory trials was significantly slower in the mature or old tooth extraction groups compared with the age-matched controls. There was no significant difference, however, between the young tooth extraction and control groups. Finally, hippocampal neuronal morphology was assessed by counting Nissl-stained cells. The number of hippocampal neurons was significantly reduced in the CA3 region in the mature and old tooth extraction groups compared with their age-matched controls, but there was no significant difference in the CA1-region or dentate gyrus between the mature or old tooth extraction groups and their age-matched controls. In young mice, there was no significant difference in the number of neurons in CA1, CA3, or dentate gyrus region between the tooth extraction and control groups. The findings indicated that tooth extraction after tooth eruption enhances the effects of aging on the hippocampus in mice.   

4

Factors influencing ridge alterations following immediate implant placement into extraction sockets  

Aim: To identify factors that may influence ridge alterations occurring at the buccal aspect of the extraction site following immediate implant placement. Material and methods: In 93 subjects, single-tooth implants were placed immediately into extraction sockets in the maxilla (tooth locations 15-25...

5

In-vitro antibacterial effects of extracts of Nigerian tooth-cleaning sticks on periodontopathic bacteria.  

Aqueous extracts from 8 plants used for tooth-cleaning in Nigeria were tested for their ability to inhibit the growth of five periodontopathic bacteria, Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Eikenella corrodens and Campylobacter rectus. Extracts of all the plants ...

6

A New 3D Contour Extraction Method for Tooth Cavity in a Dental CAD/CAM System  

In dental CAD/CAM system, tooth restoration produces customized tooth with a prepared cavity, while the prosthetic tooth fitting is firstly determined by the contour feature of the cavity, the cavity contour extraction of the tooth is one of the important issue. In order to accurately extract the cavity contour, a new Three-Dimension (3D) optimal path searching algorithm based on Intelligent Scissors theory is presented. In this algorithm, the 3D tooth is firstly formulated as a weighted model, by calculating the minimum weigh sum of the local cost from a start point to an end point in the cavity edge, the initial optimal contour can be acquired. Then through restricting the path searching range and searching direction, a desired contour can be extracted dynamically. The cases study result...

7

Management of peri-implant soft tissues between tooth and adjacent immediate implant placed into fresh extraction single socket : a one-year prospective study on two different types of implant-abutment connection desi  

This prospective study has been designed to evaluate the correlation between the presence/absence of the interproximal papilla and the mesio-distal and corono-apical position single-tooth replacement implants inserted immediately following tooth extraction. These distances have been evaluated measur...

8

Alveoplasty  

... teeth are extracted. If your dentist removes a tooth, he or she leaves an open socket that fills with a blood clot. Eventually, the ... are removed, radiation therapy cannot begin until the sockets are healed. ... if only a single tooth is removed. In these cases, radiation therapy can ...

9

Tooth extraction by orthodontic force after radiation therapy: report of case  

This report presents a therapeutic approach to orthodontic tooth extraction in a patient at high risk for the development of osteoradionecrosis with conventional techniques. The rationale for this procedure is discussed in detail, combining principles of radiation biology, clinical radiation therapy, and biomechanics of tooth movement.

10

Clinical evaluation of two-stage mandibular wisdom tooth extraction method to avoid mental nerve paresthesia  

Clinical courses following two-stage mandibular wisdom tooth extraction (TMWTE) carried out for preventing postoperative mental nerve paresthesia (MNP) were analyzed. When panoramic X-ray showed 1) overlapping of wisdom tooth root on the superior 1/2 or more of the mandibular canal, 2) interruption of the white line of the superior wall of the canal, or 3) diversion of the canal, CT examination was facilitated. In cases where contact between the tooth root and canal was demonstrated in CT examination, TMWTE was then selected after gaining the patient's consent. TMWTE consisted of removing more than a half of the tooth crown and tooth root extraction at the second step after 2-3 months. The clinical features of wisdom teeth extracted and postoperative courses including tooth movement and occurrence of MNP during two-stage MWTE were evaluated.TMWTE was carried out for 40 teeth among 811 wisdom teeth (4.9%) that were extracted from 2007 to 2009. Among them, complete procedures were accomplished in 39 teeth, and crown removal was performed insufficiently at the first-stage operation in one tooth. Tooth movement was detected in 37 of 40 cases (92.5%). No postoperative MNP was observed in cases in which complete two-stage MWTE was carried out, but one case with insufficient crown removal was complicated by postoperative MNP. Seven mild complications (dehiscence, cold sensitivity, etc.) were noted after the first-stage operation.Therefore, we conclude that TMWTE for high-risk cases assessed by X-ray findings is useful to avoid MNP after MWTE.   

11

Periodontal disease and tooth loss.  

Numerous epidemiological studies have shown that caries is the main reason for tooth loss. More recent epidemiological data seem to show an increasing trend of tooth loss due to periodontal reasons rather than caries. In considering the issue of periodontal disease and tooth loss the following observations were made. The presence of initial attachment loss, bone height and the habit of smoking significantly increase the risk of tooth mortality. There is a strong correlation between smoking, the severity of periodontal disease and tooth mortality. Cross-sectional population surveys of tooth loss reported lower anterior teeth to be the most frequently extracted due to periodontal reasons, followed by upper anteriors and upper second molars. However, in long term maintenance studies, molars were lost most frequently. Periodontal reasons for tooth loss were mainly mobility followed by furcation involvement. Periodontal surgery did not significantly enhance tooth retention in high risk groups. Ethnic differences observed were not significant and would need further investigations to address variables such as cultural differences, health habits, diet and socio-economic status. In conclusion, periodontal tooth mortality was found to be associated with the loss of periodontal attachment and risk groups with advanced periodontitis contributing to major tooth loss in a minority of the population. PMID:9779103

12

Molecular and Structural Assessment of Alveolar Bone During Tooth Eruption and Function in the Miniature Pig, Sus Scrofa  

Summary The development of alveolar bone adjacent to the tooth root during tooth eruption is not well understood. This study tested the hypothesis that predominantly woven bone forms adjacent to tooth roots during tooth eruption, but that this immature structure transitions to lamellar bone when the tooth comes into function. Additionally, bone resorption was predicted to play a key role in transitioning immature bone to more mature, load-bearing tissue. Miniature pigs were compared at two occlusal stages, 13-weeks (n-=-3), corresponding with the mucosal penetration stage of M1 tooth eruption, and 23-weeks (n-=-3), corresponding with early occlusion of M1/M1. Bone samples for RNA extraction and qRT-PCR analysis were harvested from the diastema and adjacent to M1 roots on one side. Followin...

13

astronaut tool kit contract end item specification april 1971  

Paragraph. Title. Sockets. Handles and Attacbents for Nand Socket Wrenches ..... . 9. Pliers. ..... drawers shall be vieible and easily extracted. The capability ... sional moment for each tooth of gear) shall be not greatar than. 15 inch-ounces.

14

I THE RUCKER COMPANY ""j  

S~ generation. It was decided to use two synchros operating from 600 tooth gears (at the ... During these tests it was found that the original extraction pump drive ..... cleaned up and counterbored nylock socket head screws were used in place ...

15

Why Is Oral Health Important for Women?  

... slow down the production of saliva, which allows bacteria to grow inside the mouth and bad breath to develop. More Monitor Infant's Fluoride Intake Check Menstrual Calendar for Tooth Extraction Keep ...

16

Alveolar bony crest preservation at implants installed immediately after tooth extraction: an experimental study in the dog.  

AIM: To evaluate the influence of deproteinized bovine bone mineral in conjunction with a collagen membrane, at implants installed into sockets in a lingual position immediately after tooth extraction, and presenting initial horizontal residual buccal defects socket immediately after tooth extraction may favor a low exposure of the buccal implant surface. The use of DBBM particles, concomitantly with a collagen membrane, did not additionally improve the outcome obtained at the control sites. PMID:22145914

17

Age-related changes in crown and root length in Sri Lankan Sinhalese  

Exploration of the relationship between tooth dimensions, body size, and age is important in paleontology, forensic odontology and aesthetic dentistry. It is reasonable to speculate that tooth length is associated with stature since teeth contribute to facial height. This study aimed to determine whether there was an association between tooth length and stature and age in a sample of Sri Lankan Sinhalese. Extracted teeth of adults, whose age, sex and standing height were known, were used for measurements. The total tooth length (TTL), crown length (CL) and root length (RL) of permanent maxillary central (68) and lateral (67) incisors were measured using a caliper. Statistical analyses were performed with the software MINITAB version 14.0 (Minitab Inc, USA). Mean age and standing height were 47.81 yr and 152.15 cm, respectively. There was no significant correlation between stature and tooth lengths of incisors. However, age was found to have a significant correlation with RL, (r = 0.26, P < 0.05) and CL (r = -0.28, P < 0.05). Absence of an association between tooth length and stature indicated that the genetic linkage between tooth size and stature was weak, suggesting that determination of stature from tooth lengths is unwarranted. The association between tooth length and age indicates the importance of root length in age determination. (J Oral Sci 51, 587-592, 2009)   

18

Effects of Alpha-Tricalcium Phosphate Containing Simvastatin on Alveolar Ridge Augmentation  

Augmentation of alveolar bone after tooth extraction is beneficial for subsequent prosthetic treatment. Simvastatin, a therapeutic drug for hypercholestemia, stimulates BMP-2 expression in osteoblasts and local application of simvastatin augments bone. The purpose of the present study is to examine whether local application of alpha-tricalcium phosphate containing simvastatin augments the bone of the tooth-extracted site. Porous ?-TCP rods containing different doses of simvastatin (0, 0.25, 0.50, 1.0mg) were prepared. The right mandibular incisors of rats were extracted. The tooth sockets were filled with one of the rods in the experimental groups and were not filled with the material in the control group. Animals were sacrificed at 4 and 8 weeks and the tooth-extracted sites were analyzed with soft X-ray photography, dual-energy bone absorptiometry and micro CT, and histologically examined. Bone mineral content and bone width of the tooth extracted site were significantly higher in 0.5mg and 1.0mg groups at 4 weeks and in 1.0mg group at 8 weeks than those of the control and 0mg groups. Histologically, extensive new bone formation was observed outside of the socket walls in simvastatin-applied experimental groups. The present results indicate that local application of simvastatin with ?-TCP would be potential to preserve alveolar ridge after tooth extraction although further studies are required.   

19

Current perspectives in residual ridge remodeling and its clinical implications: a review  

Objective This study aimed to evaluate the effect of an intentionally created socket on bone remodeling with orthodontic tooth movement in rabbits. Methods Eighteen male rabbits weighing 3.8 - 4.25 kg were used. An 8-mm deep and 2-mm wide socket was drilled in the bone 1 mm mesial to the right mandibular first premolar. The left first premolar was extracted to serve as an extraction socket. A traction force of 100 cN was applied to the right first premolar and left second premolar. Sections were obtained at the middle third of the moving tooth for both the drilled and extraction sockets and evaluated with hematoxylin and eosin staining and immunohistochemical analyses. The amount of tooth movement and tartrate-resistant acid phosphatase (TRAP)-positive cell count were compared between the 2 groups using the Mann-Whitney U test. Results At week 2, the distance of tooth movement was significantly higher in the intentional socket group (p extraction socket group. The number of TRAP-positive cells decreased in week 2 but increased in week 3 (p socket group showed greater distance of tooth movement than did the extraction socket group at week 2. Osteoclast counts and results of immunohistochemical analyses suggested elevated bone remodeling in both the groups. Thus, osteotomy may be an effective modality for enhancing tooth movement in orthodontic treatment. PMID:9710828

20

Optimal sinusoidal modelling of gear mesh vibration signals for gear diagnosis and prognosis  

In this paper, the synchronous signal average of gear mesh vibration signals is modelled with the multiple modulated sinusoidal representations. The signal model parameters are optimised against the measured signal averages by using the batch learning of the least squares technique. With the optimal signal model, all components of a gear mesh vibration signal, including the amplitude modulations, the phase modulations and the impulse vibration component induced by gear tooth cracking, are identified and analysed with insight of the gear tooth crack development and propagation. In particular, the energy distribution of the impulse vibration signal, extracted from the optimal signal model, provides sufficient information for monitoring and diagnosing the evolution of the tooth cracking process, leading to the prognosis of gear tooth cracking. The new methodologies for gear mesh signal modelling and the diagnosis of the gear tooth fault development and propagation are validated with a set of rig test data, which has shown excellent performance.

 
 
 
 
21

Radiolucent lesion identified in unerupted mandibular left first permanent molar: Case report and literature review  

Intracoronal resorption in an unerupted developing tooth is rare and most lesions of this type are incidentally found in radiographs taken for other purposes. A 5Y10M-old girl was referred to our clinic by a general practitioner for detailed examination of radiolucency identified in the unerupted mandibular left first permanent molar. Intraoral examination revealed that the affected tooth was unerupted, while the radiographic findings demonstrated a wide radiolucent area in the coronal part of the affected molar, which extended close to the pulp. There were no signs or symptoms associated with the tooth at the first examination. At 6Y4M of age, the affected tooth had emerged into the oral cavity, though the patient reported no symptoms. We performed surgical removal of the gingival tissue corresponding to the occlusal surface of the tooth under infiltration anesthesia and macroscopic appearance showed the affected tooth to be intact. However, when the enamel of the affected tooth was removed, a hollow portion approximately 2 mm into the tooth with no pulp exposure was revealed. Calcium hydroxide was applied to the bottom of the cavity and restoration with cement was performed. Three months after treatment, the patient had no abnormal signs or symptoms. A literature search found 15 similar cases, in which mandibular dentition was more frequently affected than maxillary dentition. As for treatment modalities in those cases, conservative restoration was preferably selected, though extraction was inevitable in approximately half.   

22

Podoplanin expression in human tooth germ tissues and cystic odontogenic lesions: an immunohistochemical study  

J Oral Pathol Med (2010) 39: 115-120 Background: Podoplanin expression was described in mouse tooth germ and apical bud cells. The aim of this study was to analyse the podoplanin expression of human tooth germ tissues, adult teeth and odontogenic lesions immunohistochemically. Study Design: Nine human tooth germ biopsies and seven healthy permanent teeth extracted for orthodontic reasons were examined. Anti-podoplanin (D2-40) reactivity was investigated immunohistochemically. Five well-defined cystic odontogenic lesions (10 radicular cysts, 10 follicular cysts, three keratocystic odontogenic tumours, five ameloblastomas, and two adenomatoid odontogenic tumours) were analysed simultaneously. Results: Podoplanin expression was detected in the majority of epithelial and ecto-mesenchymal cells...

23

Strategic considerations in treatment planning: Deciding when to treat, extract, or replace a questionable tooth  

Prosthodontists face the difficult task of judging the influence and significance of multiple risk factors of periodontal, endodontic, or prosthetic origin that can affect the prognosis of an abutment tooth. The purpose of this review is to summarize the critical factors involved in deciding whether a questionable tooth should be treated and maintained, or extracted and possibly replaced by dental implants. A MEDLINE (PubMed) search of the English, peer-reviewed literature published from 1966 to August 2009 was conducted using different keyword combinations including treatment planning, in addition to decision making, periodontics, endodontics, dental implants, or prosthodontics. Further, bibliographies of all relevant papers and previous review articles were hand searched. Tooth maintenan...

24

Construction of database for three-dimensional human tooth models and its ability for education and research - Carious tooth models -  

To construct a human teeth database which is freely available to researchers and students, three-dimensional human tooth models were generated in a previous study, by means of micro-CT, from 35 human teeth extracted during orthodontic treatment. In this study, X-ray images of 55 extracted human teeth were acquired using three-dimensional micro-CT at a resolution of 50×50×50 µm, and then visualized using a numerical data visualization software. These carious tooth models provided insight into the morphology and progression of carious defects as well as a rare insight into the morphology of carious tooth pulp, therefore rendering them as a useful tool and efficient method for dental students' learning. Moreover, these three-dimensional models could be simultaneously observed and used by many students and researchers at any one time, which was a superior advantage than having only one actual tooth for learning and study by many.   

25

Study on Tooth Extraction in Patients Maintained on Oral Anticoagulant  

We retrospectively reviewed and discussed hematostatic managements for tooth extraction in patients maintained on oral anticoagulant. From 2001 to 2007, 109 patients maintained with oral anticoagulant treatment underwent a total of 143 occasions of tooth extraction in our department. At the time of tooth extraction, oral anticoaglant medication was maintained on 76 occasions (53%), and had been discontinued on 55 occasions (38%). Postoperative bleeding happened in 5 cases (9.1%) in patients without interruption of oral anticoagulant, and in 3 cases (3.9%) in patients with interruption. There was no significant difference in the Prothrombin Time International Normalized Ratio (PT-INR) and in postoperative hemostatic procedures between them. The results of this study suggest that dental extraction can be performed without modification of oral anticoagulant treatment in cases where the PT-INR is less than 3.0. Strict local hemostatic procedures are necessary to prevent postoperative bleeding.   

26

Factors influencing ridge alterations following immediate implant placement into extraction sockets  

Abstract Aim: To identify factors that may influence ridge alterations occurring at the buccal aspect of the extraction site following immediate implant placement. Material and methods: In 93 subjects, single-tooth implants were placed immediately into extraction sockets in the maxilla (tooth locations 15-25). A series of measurements describing the extraction site were made immediately after implant installation and at re-entry, 16 weeks later. The implant sites were stratified according to four factors: (i) implant location (anterior/posterior), (ii) cause of tooth extraction (periodontitis/non-periodontitis), (iii) thickness of the buccal bone walls (1 mm) and (iv) the dimension of the horizontal buccal gap (1 mm). Results: (i) The location where the implant was placed (anterior/posteri...

27

Microbial changes after full-mouth tooth extraction, followed by 2-stage implant placement  

Abstract: Background: Recent studies showed that qPCR could detect bacteria related to periodontitis and peri-implantitis in a low concentration after full-mouth tooth extraction. This study monitored the microbiota from tooth extraction, over 9 months of full edentulism, up to 1 year after abutment connection. Material and methods: Ten patients with severe periodontitis were recruited. Six months after tooth extraction, implants were inserted. Three to 6 months later, they were connected to abutments. Plaque samples were collected from the tongue dorsum, saliva, and subgingival area (teeth/implants) before extraction up to 1 year after abutment connection, and analysed via culture, qPCR, and checkerboard technology. Results: A reduction in the total amount of aerobic and anaerobic CFU/ml ...

28

Use of viscera extract from hybrid catfish (Clarias macrocephalusxClarias gariepinus) for the production of protein hydrolysate from toothed ponyfish (Gazza minuta) muscle  

Proteolytic activity of viscera extract from hybrid catfish (Clarias macrocephalusxClarias gariepinus) was studied. The optimal pH and temperature were 9.0 and 50degreeC, respectively, when toothed ponyfish (Gazza minuta) muscle was used as a substrate. When viscera extract from hybrid catfish was used for the production of protein hydrolysate from toothed ponyfish muscle, extract concentration, reaction time, and fish muscle/buffer ratio affected the hydrolysis and nitrogen recovery (NR) (p<0.05). Optimum conditions for toothed ponyfish muscle hydrolysis were 3.5% hybrid catfish viscera extract, 15min reaction time and fish muscle/buffer ratio of 1:3 (w/v). High correlation between the degree of hydrolysis (DH) and NR (R2=0.974) was observed. Freeze-dried hydrolysate had a high protein co...

29

Study on the effects of electron beam irradiation on tooth extraction wound healing in rats. With special reference to irradiation after extraction  

The wound of the upper jaw 3 days after the first molar tooth extraction in female rats was exposed to 1,500 rads (Group 2) and 2,000 rads (Group 3) of the 10 MeV electron beams, and its pathohistological changes were compared with those of rats with the tooth extraction alone (control group). In the control group, the tooth extraction wound was covered with epithelium 10 days later and new bones were formed 17 days later. Wound healing with the epithelium was seen in all irradiated rats 24 days later. The formation of the new teeth was seen 24 days later in the Group 2 and 38 days later in Group 3. Cell infiltration under the epithelial layers was still observed in some of the Group 3, although the wound was covered with epithelium, and the new bone covering the extraction wound was formed 38 days later. Healing was prolonged in Group 3, as compared with that in Group 2.

30

Downregulated gene expression of TGF-?s in diabetic oral wound healing.  

BACKGROUND: Healing of tooth extraction sockets in poorly controlled diabetic patients is often delayed and accompanied by severe infection. The exact cellular and molecular mechanisms underlying the pathogenesis of this complication are still not fully understood. OBJECTIVES: The purpose of this study was to investigate molecular changes associated with delayed oral wound healing in diabetes. MATERIALS AND METHODS: Six to eight weeks old male type 2 diabetes and age matched control inbred mice were used and maxillary molar tooth extractions were performed. At 4 and 7 days after tooth extraction, the edentulous mucosa of the mice were harvested, and analyzed for histology and gene expression of key wound healing factors. RESULTS: In the diabetic model, histological analysis showed that epithelial tissue migration for wound closure was delayed after tooth extraction compared to the control. Quantitative real-time PCR revealed that expression of the TGF-?1, TGF-?2, TGF-?3, TGF?RII and TGF?RIII genes was significantly downregulated in the diabetic model at 4 and 7 days after tooth extraction. CONCLUSION: These results suggest that delayed wound healing of oral mucosa in diabetes may be associated with decreased expression levels of these regulatory genes which play important roles in controlling epithelial wound closure. PMID:22964221

31

Effects of Local and Whole Body Irradiation on Appearance of Osteoclasts During Wound Healing of Tooth Extraction Sockets in Rats  

We examined effects of local and whole body irradiation before tooth extraction on appearance and differentiation of osteoclasts in the alveolar bone of rat maxillary first molars. Wistar rats weighting 100 g were divided into three groups: non-irradiation group, local irradiation group, and whole body irradiation group. In the local irradiation group, a field made with lead blocks was placed over the maxillary left first molar tooth. In the whole body irradiation group, the animals were irradiated in cages. Both groups were irradiated at 8 Gy. The number of osteoclasts around the interradicular alveolar bone showed chronological changes common to non-irradiated and irradiated animals. Several osteoclasts appeared one day after tooth extraction, and the maximal peak was observed 3 days after extraction. Local irradiation had no difference from non-irradiated controls. In animals receiving whole body irradiation, tooth extraction one day after irradiation caused smaller number of osteoclasts than that 7 day after irradiation during the experimental period. Whole body-irradiated rats had small osteoclasts with only a few nuclei and narrow resorption lacunae, indicating deficiency of redioresistant osteoclast precursor cells. Injection of intact bone marrow cells to whole body-irradiated animals immediately after tooth extraction recovered to some content the number of osteoclasts. These findings suggest that bone resorption in the wound healing of alveolar socket requires radioresistant, postmitotic osteoclast precursor cells from hematopoietic organs, but not from local sources around the alveolar socket, at the initial phase of wound healing.   

32

Role of teeth adjacent to implants installed immediately into extraction sockets: an experimental study in the dog  

AIM: To evaluate the influence of the presence of both adjacent teeth on the level of alveolar bony crest at sites where implants were installed into the socket immediately after tooth extraction. MATERIAL AND METHODS: Six Labrador dogs were used. Extractions of all teeth from the second premolar to...

33

Analysis of the socket bone wall dimensions in the upper maxilla in relation to immediate implant placement  

Background: Animal and human researches have shown that immediate implant placement into extraction sockets failed to prevent socket dimensional changes following tooth extraction. It has been suggested that a minimal width of 1-2 mm of buccal bone is necessary to maintain a stable vertical dimensio...

34

Dose estimation by ESR on tooth enamel from two workers exposed to radiation due to the JCO accident  

Electron spin resonance (ESR) dosimetry is useful to estimate the external dose for the general population as well as for occupational workers in a nuclear emergency. Three teeth were extracted from two exposed workers (A and B) related to the JCO criticality accident. Tooth enamel was carefully separated from other tooth parts and subjected to ESR dosimetry. Doses equivalent to the {gamma}-ray dose of {sup 60}Co were estimated as follows: for worker A, the buccal and lingual sides of the eighth tooth in the upper right side, 11.8{+-}3.6 and 12.0{+-}3.6 Gy, respectively; for worker B, the buccal and lingual sides of the fourth tooth in the upper right side and the fifth tooth in the upper left side, 11.3{+-}3.4 and 10.8{+-}3.3 Gy, 11.7{+-}3.5 and 11.4{+-}3.4 Gy, respectively. The estimated doses were found to be similar and not dependent on the tooth positions, whether the buccal or lingual sides in each tooth. (author)

35

Gingival abscess occurring in maxillary primary central incisor fused to supernumerary tooth  

A 5Y7M-old girl was referred to our clinic by a general dentist for detailed examination of a recurrent gingival abscess in the maxillary left primary central incisor region. An intraoral examination revealed a diffuse swelling in the palatal gingiva area of the affected tooth. A periapical radiograph showed that the affected tooth was actually the primary central incisor and a supernumerary tooth, which had fused and been filled with composite resin at the juncture of the 2 tooth crowns. Removal of the filling induced severe bleeding and root canal treatment was performed. Radiographic examinations revealed 2 independent root canals, thus an additional access cavity to the mesial pulp cavity was produced for further root canal treatment. After the lesion had disappeared, root canal filling was performed using iodoform-calcium hydroxide paste and the affected tooth was restored with composite resin to fashion a single crown. However, the canal filling paste was later observed to be resorbed in the cervical area of the root. At 6Y0M, the patient received a traumatic injury in the anterior teeth region and the fused tooth was drastically displaced in a palatal direction, thus we extracted it under infiltration anesthesia. The root was observed to be wide in the mediodistal direction, and a histopathological examination revealed only dentin between 2 independent root canals. Our findings showed that the fused tooth was composed of 2 crowns and 1 root with 2 independent canals, and indicate that each crown and canal should have been treated separately.   

36

Localization of Cathepsin B and L in Rat Periodontal Tissues During Experimental Tooth Movement  

Cathepsins are common and well-characterized lysosomal cysteine proteinases involved in tissue destruction under pathological conditions. A recent immunocytochemical study reported that cathepsins B (CAB) and L (CAL) were localized in the periodontal ligament (PDL) of the rat molar. Further, our laboratory demonstrated that the levels of CAB and CAL in gingival crevicular fluid increased during orthodontic tooth movement. The present study focused on the localization of CAB and CAL during experimental tooth movement as well as participation by these cathepsins in the alteration of the periodontal tissues. Tooth movement was performed with the Waldo method, and the time points used for elastic band extraction were 1, 3, and 7 days after tooth movement. To determine localization of CAB and CAL using immunohistochemical analysis was used. Immunoreactivity for CAB and CAL was detected in osteoclasts and PDL fibroblasts. One day after tooth movement, the PDL fiber arrangement became coarse on both sides, and regressive lesions formed while the degree of staining for CAB and CAL increased in those cells as a whole. However, 3 days after tooth movement, many osteoclasts appeared in the compression and tension sides, and the immunoreactivity of CAB and CAL was increased in osteoclasts and fibroblasts. The present study demonstrated that CAB and CAL could be detected in PDL fibroblasts and osteoclasts and were increased in those cells following experimental tooth movement. Therefore, mechanical stress may be involved in extracellular matrix degradation and bone resorption through the stimulation of cathepsins, which is one of the important factors in the periodontal tissues.   

37

Influence of carbon dioxide laser irradiation on the healing process of extraction sockets  

Abstract Objective. To clarify the healing-promoting effects of carbon dioxide laser irradiation in high and low reactive-level laser therapies (HLLT and LLLT, respectively) on extraction sockets after tooth extraction. Material and methods. Forty-two 5-week-old male Wistar rats were divided into laser irradiation and non-irradiation (control) groups and compared. The laser-irradiation group underwent HLLT immediately after tooth extraction and then LLLT 1 day post-extraction. Tissue was excised 6 h and 3, 7, or 21 days after extraction and histopathologically investigated. The alveolar crest height was measured osteomorphometrically 21 days post-extraction, and granulation tissue in the extraction socket surface layer was immunohistologically investigated using anti-a-smooth muscle actin ...

38

Relationship between light and dark period activity cycles and oral condition in senescence-accelerated mice  

We investigated the effect of tooth absence and masticatory abnormalities due to powdered food feeding starting during the juvenile period on light and dark period activity cycles in senescence-accelerated mice (SAMP1) . SAMP1 were divided into 5 groups: Group 1, maxillo-mandibular molar tooth extraction; Group 2, maxillary molar tooth extraction; Group 3, mandibular molar tooth extraction; Group 4, powdered food; and Group 5, sham-operated control. Senescence was observed earliest in the powdered food group. Total 24-hour activity was higher in the control group than in the four other groups. In the powdered food group, the dark period activity decreased to less than 60% of the total activity in the 36th week. In the tooth extraction groups (Groups 1-3), dark period activity decreased to less than 60% of the total activity in the 40th week. The control group dark period activity remained above 60% for the entire experimental period. Thus, the distinction between the light and dark periods disappeared earlier in the four experimental groups compared with the control group. Significant correlations were noted among total activity, degree of senescence, and percent dark period activity in each experimental group. Functional masticatory insufficiency promoted dementia and behavioral abnormalities in SAMP1.   

39

Effects of Local and Whole Body Irradiation on the Appearance of Osteoblasts During Wound Healing in Tooth Extraction Sockets in Rats  

Irradiation before tooth extraction delays wound healing in the alveolar socket. This study examined the influences of local and whole body irradiation before tooth extraction on appearance of osteoblasts in the alveolar bone of rat maxillary first molars because bone formation is observed at the initial phase of wound healing. Several osteoblasts were generated 3 days after tooth extraction, and the number of cells increased day by day. Morphological studies showed there were little differences between local irradiation and non-irradiated controls. In contrast, the extraction wound in the whole body irradiation group showed delayed healing, and there was poor granulation tissue and very few osteoblasts at the bottom of the socket. An ultrastructural study showed that the osteoblasts in the extraction socket of whole body irradiation rats were smaller, and had poorly developed organelles. Injection of bone marrow cells to whole body-irradiated animals immediately after tooth extraction partially restored the number of osteoblasts. New periosteal bone formations outside of sockets showed little delay in the whole body irradiation group. These findings suggest that bone formation in the wound healing of extraction socket requires bone marrow cells from hematopoietic organs such as the bone marrow as well as local sources around the alveolar socket, during the initial phase of wound healing.   

40

Functional characteristics of gelatin extracted from skin and bone of Tiger-toothed croaker (Otolithes ruber) and Pink perch (Nemipterus japonicus)  

The utilization of waste from fish processing industry for production of value added products has attracted substantial attention. Tiger-toothed croaker (Otolithes ruber) and Pink perch (Nemipterus japonicus) are used for surimi production and have the potential of abundant supply of raw skins and bones. In order to evaluate the waste from Tiger-toothed croaker and Pink perch as a source of gelatin, the gelatin was extracted from skin and bones and its rheological and functional properties were examined. The skins of Tiger-toothed croaker and Pink perch yielded 7.56% and 5.57% gelatin, whereas their bones yielded 4.57% and 3.55% respectively indicating skin as an important source for gelatin production. The gel strength of gelatins from the skins and bones of Tiger-toothed croaker (170g an...

 
 
 
 
41

Frequency and characteristics of supernumerary teeth in Brazilian children: consequences and proposed treatments  

Dens invaginatus or ‘dens in dente’ is a developmental malformation of the tooth resulting from infolding of the dental papilla before calcification. This article presents a case of dens invaginatus occurring in maxillary right lateral incisor of a 45-year-old male patient. The patient presented with pain and clinically missing maxillary right canine. The tooth was found to be non-vital. Radiographic examination revealed the tooth-in-tooth appearance of lateral incisor with a dilated pulp chamber. The crown of impacted canine was found within the pulp chamber of lateral incisor. Owing to this unique clinical presentation, both the lateral incisor and the impacted canine were extracted. Histopathologic examination confirmed the diagnosis of Dens invaginatus Type III B. A brief review on etiopathogenesis, radiographic features and treatment of dens invaginatus has also been included. PMID:10023236

42

Tooth in oropharynx.  

The incidence of ectopic teeth has increased. In many cases, the etiology of ectopic teeth cannot be identified. Ectopic tooth in deciduous dentition period is very rare and information is limited about its causes and characteristics. The conditions commonly associated with an increased prevalence of ectopic teeth include cleft lip and palate, cleidocranial dysplasia, and Gardner syndrome. The diagnosis is made by the clinical and radiological examinations. The indication for extraction in ectopic teeth cases is in general determined by the presence of symptomatology, or by the need for preventing future complications. We present a case of an ectopic maxillary tooth in a 4 year-old boy. In addition, this report also addresses a young patient with a tooth in the oropharynx with the objective of non traumatic etiology, and such a clinical presentation is extremely rare. The authors believe the case presented here is the first documented case of an ectopic supernumerary tooth seen in the oropharynx. PMID:22144844

43

Protective effect on enamel demineralization of a CPP-ACP paste: an AFM in vitro study  

Objectives: The aim of the present in vitro study was the evaluation of a CPP-ACP paste (Tooth Mousse) on preventing dental erosion produced by a soft drink (Coca Cola), using Atomic Force Microscopy (AFM). Methods: Thirty extracted human central incisors free of caries were selected and divided in a treatment and a control half. The treatment halves were divided in three groups-group 1: demineralization with soft drink (4 intervals of 2min); group 2: demineralization with soft drink (4 intervals of 2min) plus Tooth Mousse; group 3: intact enamel plus Tooth Mousse. In groups 2 and 3 Tooth Mousse was applied for 3min at 0, 8, 24 and 36h. The surface of each specimen was imaged by AFM and Rrms values were registered. Results: Among treatment specimens of groups 1 and 2, a statistically signi...

44

Gamma-ray dose response of ESR signals in tooth enamel of cows and mice in comparison with human teeth  

The ESR dose responses of the tooth enamel samples prepared from teeth of cow and mice were examined in comparison with that of human. The samples were prepared with combined procedures of mechanical and chemical treatments of teeth. The ESR dose response was extracted from the total ESR spectra of tooth enamel samples by a specially developed matrix method. The dosimetric signal was found to be increased linearly with gamma dose for all studied tooth enamel samples. The radiation sensitivity of cow tooth enamel was found to be close to that of human teeth while that of mouse teeth was about 25% lower. The present results indicate that, having high radiation sensitivity, cow and mouse teeth can be used for retrospective radiation dosimetry in low-dose level.

45

Tooth Discoloration of Immature Permanent Incisor Associated with Triple Antibiotic Therapy: A Case Report  

Introduction A triple antibiotic mixture of ciprofloxacin, metronidazole, and minocycline was used as an intracanal medicament in an attempt to disinfect the root canal system for revascularization of a tooth with a necrotic pulp. However, discoloration developed after applying the triple antibiotic mixture. Methods Six weeks after a triple antibiotic paste had been applied to the root canal of tooth #8 of a 7-year-old girl, the tooth showed a dark discoloration. An in vitro experiment with human extracted teeth was performed to determine which of the 3 antibiotics caused the tooth discoloration. Another experiment was then carried out to examine whether a currently used dentin bonding agent would prevent or reduce such discoloration. The degree of discoloration was assessed by using a col...

46

Retrospective radiation dosimetry using electron paramagnetic resonance in canine dental enamel  

Electron paramagnetic resonance (EPR) biodosimetry of human tooth enamel has been widely used for measuring radiation doses in various scenarios. We have now developed EPR dosimetry in tooth enamel extracted from canines. Molars and incisors from canines were cleaned by processing in supersaturated aqueous potassium hydroxide solution. The dosimetric signal in canine tooth enamel was found to increase linearly as a function of laboratory added dose from 0.44{+-}0.02 to 4.42{+-}0.22 Gy. The gamma radiation sensitivity of the canine molar enamel was found to be comparable to that of human tooth enamel. The dosimetric signal in canine enamel has been found to be stable up to at least 6 weeks after in vitro irradiation. A dosimetric signal variation of 10-25% was observed for canines ranging from in age 3 years to 16 year old.

47

Zoledronic acid delays wound healing of the tooth extraction socket, inhibits oral epithelial cell migration, and promotes proliferation and adhesion to hydroxyapatite of oral bacteria, without causing osteonecrosis of the jaw, in mice  

Nitrogen-containing bisphosphonates such as zoledronic acid (ZOL) and pamidronate have been widely and successfully used for the treatment of cancer patients with bone metastases and/or hypercalcemia. Accumulating recent reports have shown that cancer patients who have received these bisphosphonates occasionally manifest bisphosphonate-related osteonecrosis of the jaw (BRONJ) following dental treatments, including tooth extraction. However, little is known about the pathogenesis of BRONJ to date. Here, to understand the underlying pathogenesis of BRONJ, we examined the effects of ZOL on wound healing of the tooth extraction socket using a mouse tooth extraction model. Histomorphometrical analysis revealed that the amount of new bone and the numbers of blood vessels in the socket were signi...

48

Outcomes of root canal treatment and restoration, implant-supported single crowns, fixed partial dentures, and extraction without replacement: A systematic review  

Statement of problem Dentists and patients are regularly confronted by a difficult treatment question: should a tooth be saved through root canal treatment and restoration (RCT), be extracted without any tooth replacement, be replaced with a fixed partial denture (FPD) or an implant-supported single crown (ISC)? Purpose The purpose of this systematic review was to compare the outcomes, benefits, and harms of endodontic care and restoration compared to extraction and placement of ISCs, FPDs, or extraction without tooth replacement. Material and methods Searches performed in MEDLINE, Cochrane, and EMBASE databases were enriched by hand searches, citation mining, and expert recommendation. Evidence tables were developed following quality and inclusion criteria assessment. Pooled and weighted ...

49

Comparative analysis of aspartic acid racemization methods using whole-tooth and dentin samples.  

One way to estimate biological age is to use the aspartic acid (Asp) racemization method. Although this method has been performed mostly using enamel and dentin, we investigated whether an entire tooth can be used for age estimation. This study used 12 pairs of canines extracted from both sides of the mandible of 12 individuals of known age. From each pair, one tooth was used as a dentin sample and the other as a whole-tooth sample. Amino acids were extracted from each sample, and the integrated peak areas of d-Asp and l-Asp were determined using a gas chromatograph/mass spectrometer. Statistical analysis was performed using the d/l-Asp ratio. Furthermore, teeth from two unidentified bodies, later identified as Japanese and Brazilian, were examined in the same manner. Results showed that the d/l ratios of whole-tooth samples were higher overall than those of dentin samples. The correlation coefficient between the d/l ratios of dentin samples and their age was r=0.98, and that of the whole-tooth samples was r=0.93. The difference between estimated age and actual chronological age was -0.116 and -6.86years in the Japanese and Brazilian cases, respectively. The use of whole teeth makes the racemization technique easier and can standardize the sampling site. Additionally, using only a few tooth samples per analysis made it possible to reanalyze known-age samples. Although the difficulty in obtaining a proper control sample has prevented racemization from being widely used, the method described here not only ensures the availability of a control tooth, but also enables the teeth to be used for other purposes such as DNA analysis. The use of a whole tooth will increase the application of the racemization technique for age determination. PMID:22989598

50

Novel Endovascular Treatment of Enlarging Facial Artery Pseudoaneurysm Resulting From Molar Extraction: A Case Report  

Purpose A novel endovascular therapy to treat a pseudoaneurysm as a complication of molar tooth extraction is described. Patients and Methods A 20-year-old man presented 2 weeks after third molar tooth extraction with an enlarging pulsatile jaw mass, identified as a facial artery pseudoaneurysm. Endovascular embolization with microcoils and a liquid embolic agent, Onyx, was performed. The use of Onyx in this manner is an off-label use. Results Immediately after treatment, the pulsatile mass resolved and remained obliterated at 2 months of follow-up. Conclusions Onyx embolization of facial artery vascular lesions can be safely accomplished while avoiding microvascular complications and provides a satisfactory and durable result.

51

Effects of alendronate on bone healing after tooth extraction in rats  

Oral Diseases (2010) 16, 674-685 Objectives: Tooth extraction has been identified as an important risk factor for bisphosphonate-induced osteonecrosis of the jaw. Therefore, the main goal of this study was to determine the effects of alendronate on healing of the extraction socket and on interdental alveolar bone after tooth extraction in rats. Materials and methods: Animals were injected subcutaneously with vehicle or alendronate for 3-4 weeks before the first mandibular molar was extracted and these treatments were continued during post-extraction periods of 10, 21, 35 and 70 days. Mandibles were processed to evaluate healing of the extraction socket and adjacent alveolar bone by assessing bone formation, bone resorption and vascularity by histomorphometric techniques. Results: Alendrona...

52

Clinical and histomorphometric evaluation of extraction sockets treated with an autologous bone marrow graft  

Abstract Purpose: The aim of this study was to evaluate the potential of an autologous bone marrow graft in preserving the alveolar ridges following tooth extraction. Materials: Thirteen patients requiring extractions of 30 upper anterior teeth were enrolled in this study. They were randomized into two groups: seven patients with 15 teeth to be extracted in the test group and six patients with 15 teeth to be extracted in the control group. Hematologists collected 5 ml of bone marrow from the iliac crest of the patients in the test group immediately before the extractions. Following tooth extraction and elevation of a buccal full-thickness flap, titanium screws were positioned throughout the buccal to the lingual plate and were used as reference points for measurement purposes. The sockets ...

53

Relationship between Intake of Vegetables, Fruit, and Grains and the Prevalence of Tooth Loss in Japanese Women  

Epidemiological evidence regarding dental status and its relationship to diet and nutritional status has been limited. The present cross-sectional study examined the relationship between intake of vegetables, fruit, grains, antioxidants, and fiber and the prevalence of tooth loss. Study subjects were 1,002 pregnant Japanese women. Tooth loss was defined as the previous extraction of 1 or more teeth. Adjustment was made for age, gestation, parity, cigarette smoking, passive smoking at home and at work, family income, education, changes in diet in the previous 1 mo, season when data were collected, and body mass index. Of the 1,002 subjects, 256 women had lost 1 or more teeth. Compared with intake of vegetables other than green and yellow vegetables in the lowest quartile, consumption of the other vegetables in the highest quartile was independently associated with a decreased prevalence of tooth loss, showing a clear inverse dose-response relationship. There was a marginally significant inverse dose-response relationship between the intake of insoluble fiber and tooth loss. No association was observed between intake of green and yellow vegetables, soluble fiber, or antioxidant nutrients and tooth loss. These findings suggested that consumption of vegetables other than green and yellow vegetables and insoluble fiber may be related to a decreased prevalence of tooth loss among young Japanese women.   

54

Effects of early tooth extractions on hippocampal GFAP-positive cells in aged senescence-accelerated mice  

The effects of early tooth extractions on age-associated changes in cognitive function were evaluated. Specifically, teeth were extracted at an early age in senescence-accelerated mice (SAM)P8, and the number of glial fibrillary acid protein (GFAP)-positive astrocytes and spatial perception were evaluated at young, mature, and old ages. The following results were obtained:1. Concerning spatial perception evaluated by the Morris water maze test, the shortening of the time until the animals reached the platform was significantly slower in mature or old mice of the tooth extraction group compared with age-matched controls. However, no significant difference was noted in the rate of shortening in young mice between the tooth extraction and control groups.2. The number of GFAP-positive cells was significantly higher in the CA3 region of the hippocampus in the mature or old mice of the tooth extraction group compared with age-matched controls. However, no significant difference was observed in the CA1 and dentate gyrus (DG) region of the hippocampus in the mature or old mice and in the CA1, CA3, and DG region in the young mice between the two groups.These results suggest that the loss of teeth at an early age accelerated aging and that GFAP-positive astrocytes increased to compensate for a decrease in pyramidal cells.   

55

Effect of toothbrushing with different manual toothbrushes on the shear bond strength of orthodontic brackets  

Abstract in english The aim of this study was to evaluate the effect of brushing with a Colgate 360º or Oral B Indicator 35 toothbrush on the shear bond strength of orthodontic brackets bonded to extracted human teeth. The bristle wear and bristle tip morphology were also examined after simulated tooth-brushing. Orthodontic brackets (Roth-P/1st and 2nd premolar S/D- Slot 0.18") were bonded (Transbond XT®) to the smoothest surface of each of 45 extracted human molar and premolar teeth. Test (more) specimens were randomly divided into three groups: Group 1, control group with no brushing; Group 2, brushing with the Oral B Indicator 35; Group 3, brushing with the Colgate 360º. Samples were adapted to a machine that simulated tooth-brushing. The bond strength of each bracket to each tooth was assessed with a mechanical testing machine. The bristle wear and bristle tip morphology indices were also assessed. Statistically significant differences were defined for p

56

Analysis of the pattern of the alveolar ridge remodelling following single tooth extraction  

Abstract Introduction: Tooth extraction is followed by marked osseous changes of the residual alveolar ridge including severe bone alterations both in height and in width. However, such remodelling could jeopardize the subsequent implant insertion for two main reasons. Firstly, the absence of adequate bone levels makes implant placement impossible; secondly, aesthetic problems in the fabrication of implanto-supported restoration could be caused by serious bone re-absorption. Thus, it is of crucial importance that the dental surgeon knows how the alveolar crest changes when a single tooth has been removed. The aim of this study was to evaluate the pattern of alveolar crest remodelling observed in a single intercalated area of tooth extraction after at least a period of 6 months of healing, ...

57

Ridge preservation and augmentation using regenerative materials to enhance implant predictability and esthetics.  

Dentistry has entered an era in which patients no longer need to accept an edentulous or partially edentulous condition, or one in which their candidacy for tooth structure replacement (ie, implants with subsequent restoration) must be dismissed because of insufficient alveolar bone volume, height, or width. The supporting bone can be preserved at the time of tooth extraction, or augmented at the time of case presentation, using a variety of available regenerative materials. Among them are mineralized human allograft bone and collagen membranes that can be placed in combination with specific growth factor complexes and implant designs. This article reviews the challenges associated with adequately preserving or augmenting the alveolar bone after tooth extraction or loss and before implant placement. The research and benefits to support using allogenic bone graft and membrane materials for such procedures are detailed, and 3 clinical cases are presented to demonstrate the clinically successful incorporation of these materials with the host tissues. PMID:18064786

58

American College of Prosthodontists  

... Jaw Pain Misshapen Tooth/Teeth Missing Tooth/Teeth Oral Cancer Oral Piercing Osteonecrosis of the Jaw Peg lateral incisors (tooth/teeth) Periodontitis Sleep Apnea Spots on Mouth/Tongue TMJ/TMD Tooth/Teeth Abscess Toothache Tooth/Teeth ...

59

Healing of tooth extraction sockets in the streptozotocin diabetic rat model: Induction of cartilage by BMP-6  

Cartilage does not form in the tooth extraction socket of the normal rat. The aim of the study was to determine if adding BMP-6 to the extraction socket would cause chondrogenic differentiation in the diabetic rat. A group of 8-week-old rats were injected intraperitoneally with a diabetogenic agent, streptozotocin, and a control group received citrate buffer only. Three weeks later, the maxillary molar teeth were extracted and either BMP-6 or saline applied to the extraction sockets. Rats from each group were killed on days 3, 5, 7, and 9 after tooth extraction. In the diabetic rats treated with BMP-6, there was a cellular subperiosteal reaction at day 3 in the extra-alveolar tissues, which by day 7 had formed a large mass of cartilage. Cartilage was induced in the subperiosteal region of ...

60

Deproteinized bovine bone mineral in marginal defects at implants installed immediately into extraction sockets: an experimental study in dogs  

AIM: To evaluate the influence of deproteinized bovine bone mineral (DBBM) particles concomitant with the placement of a collagen membrane on alveolar ridge preservation and on osseointegration of implants placed into alveolar sockets immediately after tooth extraction. MATERIAL AND METHODS: The pul...

 
 
 
 
61

0  

allow the astronauts to monitor the socket engine and attitude control system and ..... venient method is to rotate a gear tooth wheel and use a magnetic pickup to ..... cold gas and after the engine startup begins the hot gas is extracted from the ...

62

Short implants (6 mm) installed immediately into extraction sockets: an experimental study in dogs  

AIM: To evaluate the effect of implant length (6 mm vs.11 mm) on osseointegration (bone-to-implant contact) of implants installed into sockets immediately after tooth extraction. MATERIAL AND METHODS: In six Labrador dogs, the pulp tissue of the mesial roots of (3) P(3) was removed and the root cana...

63

Dry Socket (Alveolar Osteitis)  

... pills. It occurs after 3% to 5% of tooth extractions. It is more common after the removal of premolar or molar teeth, especially impacted wisdom teeth (third molars) in the lower jaw. Symptoms Dry socket causes pain in and around the site where ...

64

A case of extensive osteonecrosis on the maxilla caused by tooth extraction under chemotherapy  

We report a case of severe extensive osteonecrosis after tooth extraction in a patient undergoing chemotherapy with anticancer drugs.A 63-year-old male, who had received combination chemotherapy for mantle cell lymphoma, was referred to our department because of pain in the right mandible. The patient was diagnosed as alveolar ostitis and treatment was started. During this treatment, the chemotherapy was discontinued because the patient complained of severe pain in the right maxilla. Therefore, tooth extraction under local anesthesia was performed to remove the cause of the pain. Dry sockets occurred after the tooth extraction but the chemotherapy had to be restarted for his mantle cell lymphoma. Necrosis of gingiva and bone in the right maxilla appeared after restarting chemotherapy. CT scan revealed extensive osteonecrosis in the right side of the maxilla. Conservative treatments with antibiotics, irrigation, and hyperbaric oxygen therapy were administered, but the osteonecrosis extended. Sequestrectomy of the right maxilla was carried out under general anesthesia, and histopathological examination confirmed sequestrum of the resected bone. The postoperative course after the operation was uneventful.We consider that tooth extraction in patients receiving combination chemotherapy with anticancer drugs may cause serious complications.   

65

Influence of implants with different sizes and configurations installed immediately into extraction sockets on peri-implant hard and soft tissues: an experimental study in dogs  

AIM: To study the influence on the healing of soft and hard peri-implant tissues when implants of different sizes and configurations were installed into sockets immediately after tooth extraction. MATERIAL AND METHODS: Transmucosal cylindrical implants, 3.3 mm in diameter in the control sites, and c...

66

A HISTOMORPHOMETRIC STUDY OF ALVEOLAR BONE HEALING IN RATS FED A BORON-DEFICIENT DIET  

Bone healing after tooth extraction in rats is a suitable experimental model to study bone formation. Thus, we preformed a study to determine the effects of boron deficiency on bone healing by using this model. Weanling Wistar rats were divided into two groups: control (G1; 3 mg B/kg diet), and bo...

67

[Pseudopathology of hemostasis in dental practice].  

The authors demonstrate, with a 66 patients research, that also when laboratory tests on hemostasis indicate pathology like XII factor penia, disfibrinogenemy, lupus (Lac), pyastrinopenia, we manage pseudopathology. In these cases haemostasis is completely normal, even after surgery, like tooth extraction. PMID:2639799

68

Alveolar wound healing after x-irradiation: a histologic, radiographic, and histometric study  

Healing of extraction wounds in rats following cephalic irradiation was studied by histologic, radiographic, and histometric methods 14 days after tooth extraction. Irradiation was given at 0, 3, and 7 days after surgery in doses of either 15, 20, or 30 Gy. No significant differences were seen with the different doses given seven days post-extraction. However, socket healing was delayed when irradiation was given immediately and three days after extraction. On the basis of these observations, it is recommended that radiation not begin until at least one week after the extraction of teeth.

69

Dynamics of Bio-Oss Collagen incorporation in fresh extraction wounds: an experimental study in the dog  

Abstract Aim: The objective of this experiment was to analyze processes involved in the incorporation of Bio-Oss Collagen in host tissue during healing following tooth extraction and grafting. Methods: Five beagle dogs were used. Four premolars in the mandible (3P3, 4P4) were hemi-sected, the distal roots were removed and the fresh extraction socket filled with Bio-Oss Collagen. The mucosa was mobilized and the extraction site was closed with interrupted sutures. The tooth extraction and grafting procedures were scheduled in such a way that biopsies representing 1 and 3 days, as well as 1, 2 and 4 weeks of healing could be obtained. The dogs were euthanized and perfused with a fixative. Each experimental site, including the distal socket area, was dissected. The sites were decalcified in E...

70

Vertical and horizontal ridge alterations after tooth extraction in the dog: flap vs. flapless surgery  

Abstract Objective: To compare ridge alterations after flap and flapless tooth extraction in the vertical and horizontal dimension in the dog model. Material and methods: This study was carried out on five Beagle dogs. Four extractions were performed in the lower jaw of each dog (two per side. Pm3, Pm4). At the time of tooth extraction, flap surgery was performed on one side (control group). On the contra-lateral side, a flapless extraction was performed (test group). Mesial sockets were left untreated on both sides. After 3 months of healing, the dogs were sacrificed and prepared for histological analysis. Results: Ten samples were evaluated on each group. The vertical difference in height between the buccal and lingual crest was 1.48-mm for the flap, and 1.22-mm for the flapless group. T...

71

Superpulsed laser therapy on healing process after tooth extraction in patients waiting for liver transplantation  

Alveolar healing following tooth extraction is a complex repair process involving different tissues, including epithelium and bone. This research aimed to study the effect of laser therapy on alveolar healing process in patients waiting for liver transplantation, evaluating some inflammation, osteogenesis, and clinical parameters. Twelve patients with hepatic failure waiting for liver transplantation, with indications to bilateral extraction, entered the split-mouth study. One post-extractive defect was treated with laser while the other was left without treatment. Specimens of soft tissues were removed from around the tooth before extraction and after 7 days. Superpulsed laser irradiation prevented IL-1? increase and induced IL-6, IL-10, and collagen III increase at 7 days in compariso...

72

Mutual wear evaluation of resin composites when opposing enamel and dentin  

Mutual wear rates of resin composites and both superficial and deep layers of enamel and dentin were investigated by means of an in vitro wear test. Occlusal surfaces of extracted molars were ground flat to respective layers of enamel and dentin. Hemispherical-shaped styli (n = 8) made of microfilled and microhybrid composites were placed perpendicular to the finished tooth surface (600 grit) in the presence of tap water, and a two-body wear test (75 N load and 1.2 Hz) was performed for 100,000 cycles. The wear depths on both tooth and composite specimens were determined, and the data were statistically analyzed by two-way ANOVA and Boneferroni test (p

73

Natal primary molar: clinical and histological aspects  

The authors report a case of natal primary molar in a healthy 14-day-old child. The diagnosis of the case and the treatment plan are discussed, as well as histological analyses of the natal tooth. The tooth presented an immature appearance, with high mobility and insertion only in soft tissue, and therefore the clinical option adopted was dental extraction. Histological analyses revealed enamel hypoplasia and dentin showing a typical tubular pattern without alterations. The soft tissue had young and richly vascularized pulp with areas of chronic inflammatory infiltration. (J Oral Sci 52, 313-317, 2010)   

74

Extracting Structural Information of a Heteropolymer from Force-Extension Curves  

We present a theory for the reverse analysis on the sequence information of a single H/P two-letter random hetero-polymer (RHP) from its force-extension(f-z) curves during quasi static stretching. Upon stretching of a self-assembled RHP, it undergoes several structural transitions. The typical elastic response of a hetero-polymeric globule is a set of overlapping saw-tooth patterns. With consideration of the height and the position of the overlapping saw-tooth shape, we analyze the possibility of extracting the binding energies of the internal domains and the corresponding block sizes of the contributing conformations.

75

Tooth thickness at the furcation entrance of lower molars.  

Better understanding of the furcation anatomy may serve to decrease the risk of pulpal injury during rotary odontoplasty, a procedure often used in conjunction with guided tissue regeneration. The purpose of this study was to determine (i) the tooth thickness about the furcation entrance of lower molars, and (ii) whether there is a relationship between tooth thickness and patient age. 40 mandibular 1st molars (M1) (mean age = 36.2; range 10-65 years) and 40 mandibular 2nd molars (M2) (mean age = 37.9; range 14-70 years) were collected. Age, gender and furcation involvement (if any) were noted for each tooth at the time of extraction. Teeth were sectioned in half, buccal-lingual, at the furcation entrance with a rotary diamond blade. A standardized linear reference scale was placed on each experimental section and an 8 x 10 in. photograph generated. The distance from the floor of the pulp chamber to 5 predetermined sites on the root surface was calculated. The data were expressed as (a) the mean of each site and (b) the mean of each tooth (the average of the 5 points of each tooth). Analysis of covariance failed to show a relationship between thickness measurements and gender or furcation involvement. Thus, the data was subjected to simple regression analysis to determine the relationship of age with tooth and cementum thickness. This study revealed that by site, the mean measurements ranged from 2.7-3.0 mm for both M1 and M2. The single least/greatest measurements of the 5 sites were for M1: 1.6/4.7 mm and for M2: 1.8/4.2 mm. By tooth, the average distance from the pulp to the root surface was 2.83 mm (+/- 0.49) for M1 and 2.88 mm (+/- 0.44) for M2. Regression analysis of tooth thickness with age was significant for M1 only. The maximum slope of the 5 sites was approximately 0.3 mm/10 years. No relationship was found between cementum thickness and age for either tooth group. The results of this study indicate that the majority of times the pulp is 1.6-4.2 mm from the root surface in the vicinity of the furcation entrance of lower 1st and 2nd molars. Although tooth thickness in this area may increase with age, the amount is not enough to forego judicious odontoplasty on older patients. PMID:8841893

76

Single-tooth replacement by immediate implant and connective tissue graft: a 1-9-year clinical evaluation  

When performing a tooth extraction, imminent collapse of the tissue by resorption and remodeling of the socket is a natural occurrence. The procedure for the preservation of the alveolar ridge has been widely described in the dental literatures and aims to maintain hard and soft tissues in the extraction site for optimal rehabilitation either with conventional fixed or removable prosthetics or implant-supported prosthesis. PMID:15142088

77

Effect of irradiation on wound healing after tooth extraction in the rachitic rats  

To observe the histopathological changes following irradiation on the wound healing after tooth extraction in the rachitic rats. In order to carry out this study, the rats were divided into four groups: Group 1 (normal diet/non-irradiation group), Group 2 (normal diet/irradiation group), Group 3 (rachitogenic diet/non-irradiation group), and Group 4 (rachitogenic diet/irradiation group). Rachitic changes were induced with rachitogenic diet No. 2 (high calcium, low phosphorus, and Vitamin D deficient diet) for 5 weeks. After the extraction of both maxillary first molars of the rats in Group 2 and 4, the head and neck of the rats were irradiated with single absorbed dose of 10 Gy. The rats were sacrificed at the 1st, 5th, 10th, and 15th day after tooth extraction. The specimens including the extraction wound were sectioned, stained with the hematoxylin-eosin and Masson's trichrome method and examined under the light microscope. In the Group 2, the amount of newly formed bone trabeculae on the periphery of extraction socket and osteoblastic activity were reduced. In the Group 3, epithelial fusion was not revealed on the 5th day after toothe extraction and growth rate of osteoid formation was reduced. In the Group 4, necrotized tissue at the outer surface of extraction socket and destructive changes on the alveolar bones were noted on the 10th day. Epithelial fusion was not revealed and large amounts of osteoclast were noted on alveolar bone on the 15th day. The healing process of wound after tooth extraction was retarded by irradiation and especially in the rachitic rats.

78

Molecular and structural assessment of alveolar bone during tooth eruption and function in the miniature pig, Sus scrofa  

Summary The development of alveolar bone adjacent to the tooth root during tooth eruption is not well understood. This study tested the hypothesis that predominantly woven bone forms adjacent to tooth roots during tooth eruption, but that this immature structure transitions to lamellar bone when the tooth comes into function. Additionally, bone resorption was predicted to play a key role in transitioning immature bone to more mature, load-bearing tissue. Miniature pigs were compared at two occlusal stages, 13 weeks (n=3), corresponding with the mucosal penetration stage of M1 tooth eruption, and 23 weeks (n=3), corresponding with early occlusion of M1/M1. Bone samples for RNA extraction and qRT-PCR analysis were harvested from the diastema and adjacent to M1 roots on one side. Following euthanasia, bone samples for hematoxylin and eosin and TRAP staining were harvested from these regions on the other side. In contrast to expectations, both erupting and functioning molars had reticular fibrolamellar structure in alveolar bone adjacent to M1. However, the woven bone matrix in older pigs was thicker and had denser primary osteons. Gene expression data and osteoclast cell counts showed a tendency for more bone resorptive activity near the molars than at distant sites, but no differences between eruptive stages. Thus, although resorption does occur, it is not a primary mechanism in the transition in alveolar bone from eruption to function. Incremental growth of existing woven bone and filling in of primary osteons within the mineralized scaffold generated the fortification necessary to support an erupted and functioning tooth.

79

Modified distal wedge excision for access and treatment of an infrabony pocket in a dog.  

A six-year-old male neutered Dachshund dog presented with generalized moderate gingivitis and calculus formation. A comprehensive oral examination performed under general anesthesia revealed infrabony pockets and horizontal bone loss associated with the left mandibular first and second molar teeth. The left mandibular second molar tooth was extracted, while the left mandibular first molar tooth was treated by staged periodontal therapy, including a modified distal wedge excision for open root planning and bone augmentation. Preoperative probing depths of 9-mm associated with the distal root of the left mandibular first molar tooth were reduced to 2-mm following treatment. The patient continued to maintain normal periodontal probing depths, with no gingival recession at 3, 6, 16, and 33-months following periodontal treatment. PMID:20469791

80

Homeostasis and Regeneration of the Periodontal Ligament  

Homeostatic and reparative functions of the periodontal ligament are most significant in respect to periodontal therapy and transplantation and/or replantation of tooth. Based on our experimental studies and currently published studies, this review article discusses the mechanism of both tissue regeneration and homeostatic function of the periodontal ligament from the viewpoint of periodontal treatment and tooth transplantation. The involvement of cell proliferation, differentiation, growth factors, microenvironment including the guided tissue regeneration, osteogenic progenitor cells, bone morphogenetic protein are discussed. In relation to transplantation or replantation of tooth and periodontal regeneration, we describe the following characteristics of the periodontal ligament; volume of the periodontal ligament attached to root surface of extracted teeth, characteristics of cells in the periodontal ligament, cell constituting the regenerated periodontal ligament, mechanism maintaining a certain width, particularly the function of Malassez's epithelial rests and mechanism of ankylosis.   

 
 
 
 
81

A comparison between adipose tissue and dental pulp as sources of MSCs for tooth regeneration  

In this study, several in vivo and in vitro comparisons were performed to test the possibility of using adipose-derived stem cells (ADSCs), a more convenient cell source than dental pulp stem cells (DPSCs), in tooth regeneration. Using an efficient, non-engineering implantation method, we first demonstrated that both implants of ADSCs and DPSCs were able to grow self-assembled new teeth in adult rabbit extraction sockets with high success rate. The stem cells were necessary because the implants grew no tooth without them. A stepwise comparison showed that the regenerated teeth from these two types of adult stem cells were living with nerves and vascular system and remarkably similar to a normal tooth in many details. Further strictly controlled, side-by-side comparisons between the two typ...

82

The 4th international comparison on EPR dosimetry with tooth enamel  

This paper presents the results of the 4th International Comparison of in vitro electron paramagnetic resonance dosimetry with tooth enamel, where the performance parameters of tooth enamel dosimetry methods were compared among sixteen laboratories from all over the world. The participating laboratories were asked to determine a calibration curve with a set of tooth enamel powder samples provided by the organizers. Nine molar teeth extracted following medical indication from German donors and collected between 1997 and 2007 were prepared and irradiated at the Helmholtz Zentrum Munchen. Five out of six samples were irradiated at 0.1, 0.2, 0.5, 1.0 and 1.5 Gy air kerma; and one unirradiated sample was kept as control. The doses delivered to the individual samples were unknown to the particip...

83

Histologic Observation of a Human Immature Permanent Tooth with Irreversible Pulpitis after Revascularization/Regeneration Procedure  

IntroductionHistological studies of immature human permanent necrotic teeth with or without apical periodontitis after revascularization have not been reported. This case report describes the histological findings of tissue formed in the canal space of an immature permanent tooth #9 with irreversible pulpitis without apical periodontitis after revascularization. MethodsAn immature human permanent tooth #9 was fractured 3.5 weeks after revascularization and could not be retained. The tooth was extracted and prepared for routine histological and immunohistochemical evaluation in order to examine the nature of tissue formed in the root canal following the revascularization procedure. ResultsAt 3.5 weeks after revascularization, more than one half of the canal was filled with loose connective ...

84

The design and development of surgical templates for premolar transplants in adolescents  

Abstract The aim of designing and fabricating the surgical templates was to assist the surgical component of premolar transplantation, by establishing and replicating the root dimensions of the donor premolar tooth. The correct template could be used to assess the socket preparation (width and depth) prior to placement of the transplant in the recipient site, obviating the need to repeatedly try the donor tooth for fit at the recipient site, thereby minimising trauma to the periodontal ligament of the donor tooth. Seventy-five mandibular premolars and 50 maxillary second premolars were selected with varying stages of root development. All teeth had been extracted for orthodontic reasons. The root was measured for its length (maxL) and maximum (maxW) and minimum width (minW) with digital ca...

85

Management of the malposition tooth that was caused by dentigerous cyst associated with impacted supernumerary tooth by using an obturator  

This report presents a case of eruption guidance for an upper right central incisor with a dentigerous cyst associated with an impacted supernumerary tooth in a 5-year-9-month-old boy. A swelling was seen in the region of an upper right central incisor. Radiographic examinations showed that a well-defined cystic lesion, containing an impacted supernumerary tooth crown in it, was located between the root of the primary upper right central incisor and a permanent upper central incisor germ. Under general anesthesia, the dentigerous cyst was removed at extraction of the upper impacted supernumerary tooth. And then, a socket was kept open wound. A histopathological examination confirmed the diagnosis of a dentigerous cyst associated with a supernumerary tooth. By using an obturator, we guided eruption of an upper right central incisor with malposition that was caused by the dentigerous cyst, and observed the way of the tooth eruption for two years and seven months. The obturator was inserted in the socket directly for three months until it was closed. After that, the obturator was used as only a removable space maintainer. Eight months after the operation, the obturator was removed because the upper left central incisor began to erupt. Two years and seven months after the operation, both upper central and lateral incisors had erupted completely. In this case, the obturator was used for expectation of natural eruption of permanent incisors, space maintenance and aesthetic recovery. The permanent incisors had been able to be guided to almost correct position without traction.   

86

Results of tooth enamel EPR dosimetry for population living in the vicinity of the Semipalatinsk nuclear test site  

The method of electron paramagnetic resonance (EPR) dosimetry was used on human tooth enamel to obtain individual absorbed doses of residents of settlements in the vicinity of the Nuclear Test Site (SNTS) in Semipalatinsk region, Kazakhstan. Measured teeth were extracted according to medical indications. In total, 105 tooth enamel samples were analyzed, including eight tooth samples from control settlement Kokpekty, which is located 400 km to the Southeast from SNTS and was not subjected to any radioactive contamination. It was found that the excess doses obtained after subtraction of the contribution of natural background radiation ranged up to about 440 mGy for residents of Dolon, whose tooth enamel was formed before 1949, and do not exceed 100 mGy for younger residents. For residents of Mostik, excess doses do not exceed 100 mGy for all ages except in one resident, for whom an extremely high dose of 1250 mGy was registered. For Bodene settlement, excess doses higher than 100 mGy were obtained for two samples from the residents having enamel formed before 1949. An extremely high dose (2800{+-}400 mGy) was obtained for one resident of Semipalatinsk City. The average excess dose for Semipalatinsk samples with enamel formation before 1949 was determined close to the average excess dose for tooth enamel samples from Dolon village.

87

Application of Isolite system during treatment of dental caries identified in submerged mandibular second primary molar  

We used the Isolite system for treatment of dental caries identified in a submerged mandibular right primary second molar. A 5-year-6-month-old girl was referred to our clinic for close examination of an impacted mandibular right second primary molar. An intraoral examination showed a slight pit extending inside the gingiva and on the occlusal surface of the tooth. X-ray photographic examination revealed that the affected tooth was severely submerged and had a radiolucent area on the occlusal surface, which extended close to the pulp cavity. Most of the periodontal ligament space could not be clearly identified except for the distal side of the distal root. We considered that the area of the tooth was partially ankylosed and consulted with oral surgeons, who decided to postpone extraction, due to the presence of the permanent successor close to the affected tooth. Thus, we treated the dental caries, which appeared to be technically difficult because of the deep location of the tooth. The Isolite system was utilized in this case, as we considered that adjacent soft tissue and saliva could be excluded with its use. Under infiltration anesthesia, gingival tissue covering the occlusal surface was removed with an electric knife, and the carious lesion was removed, which resulted in pulp exposure. Severe inflammation of the pulp was revealed and pulpectomy was performed. There were no signs and symptoms after the treatment. At 1 year after treatment, the occlusal surface remained exposed and no inflammatory findings were observed in adjacent gingival tissue.   

88

Inspection of Tooth Surface Geometry by Means of Vibration Measurement  

Tooth surface undulation is one of the important sources of gear noise and vibration. The vibration caused by this source is observed as the occurrence of non-meshing vibration component or ghost noise on a vibration spectrum. Frequently ghost noise occurs at the same frequency with natural frequency of a gear pair, consequently its amplitude is amplified to the considerable level and lead to unexpected and severe noise and vibration problems. In this paper a method for inspecting tooth surface undulation is proposed and applied to a helical gear pair. Vibration characteristics of individual gear are extracted from the vibration signal of a gear by synchronous averaging technique, then a frequency response function that can be determined experimentally is applied to the individual averaged signal to assess the tooth surface undulation. The undulations are evaluated by applying this method to the measured vibration signals of the gear pair operated at various speeds and various torques, and show good agreement with each other regardless of operating conditions and also with the expectation by precise tooth surface measurement, even though the undulation is very small in the level of 0.1µm. These results suggest the ability of this method to assess the tooth surface geometry relevant to vibration.   

89

Tooth replantation as an alternative to dental implantology in adolescent patients.  

BACKGROUND: A 16-years old female patient was referred to our observation in July 2006, 14 days after an accident, with traumatic intrusive luxation of the right upper central incisor that caused the nasal floor and buccal cortical bone fracture. While the extraoral examination showed the traumatic lesions of the upper lip, the intraoral examination revealed intrusive luxation, pain and high mobility of the tooth, and bleeding of the adjacent oral tissue. The treatment protocol consisted in surgical buccal bone removal, tooth extraction, retrograde root-canal filling, and tooth repositioning in occlusion with a resilient splinting. After 8 weeks the splinting was removed, and clinical and radiological examinations were taken 3, 6, 9, 12, and 24 months after surgery. At the 24 months follow-up the root showed no radiographic signs of inflammation, resorption or ankylosis, and the function of the replanted tooth was fully maintained. Tooth replantation can be considered an effective alternative to dental implant, when the latter is contraindicated in young patient with incomplete skeletal development. The long-term success of the procedure will likely require a multidisciplinary approach. PMID:21250776

90

A Review on Alveolar Ridge Preservation Following Tooth Extraction  

Context The question that clinicians face is whether the use of bone replacement grafts and/or barrier membranes enhance their ability to provide for the future placement of a dental implant or to maximize ridge dimensions following the extraction of a tooth versus no additional treatments. Evidence Acquisition The evidence was obtained by search of Entrez PubMed and manual search of The International Journal of Oral and Maxillofacial Implants, The International Journal of Periodontics & Restorative Dentistry, Clinical Oral Implant Research, The Journal of Periodontology, The Journal of Clinical Periodontology, and The Compendium of Continuing Education in Dentistry. Key search words included Guided Bone Regeneration, Dental Extraction, Tooth Extraction, Bone Replacement Graft, Alveolar Ri...

91

Immediate Implant Placement: A Case Report  

This case report describes extraction of a fractured left maxillary lateral incisor tooth, followed by immediate placement of a dental implant in the prepared socket and temporization by a bonded restoration. The tooth was atraumatically extracted, the socket was prepared to the required depth and a Biohorizon Implant was inserted followed a week later by temporization by a bonded restoration. An impression was made 4 months after implant insertion, and a definitive restoration was placed. The atraumatic operating technique and the immediate insertion of the Implant resulted in the preservation of the hard and soft tissues at the extraction site. The patient exhibited no clinical or radiologic complications through 5 years of clinical monitoring. The dental implant and provisional restorat...

92

In vivo assessment of osseous wound healing using a novel bone putty containing lidocaine in the surgical management of tooth extractions.  

Objective. This preclinical pilot study evaluated the systemic, radiographic, and histological responses to bone putty containing lidocaine in a canine tooth extraction model. Methods. In five beagle dogs the right mandibular premolars were extracted and sockets grafted with (1) xenograft particulate bone and a collagen sponge plug (control), (2) bone putty alone, (3) bone putty mixed with xenograft (3?:?1), or (4) xenograft sandwiched between bone putty. At 6 weeks post-op, the systemic and local responses were evaluated using a blood chemistry panel, micro-CT, and histological analyses. Results. No significant differences in blood chemistries were noted at 6 weeks postgrafting compared to baseline. Sockets grafted with either bone putty formulation demonstrated comparable radiographic and histologic evidence of bone healing compared to control sockets. Conclusions. Our preclinical results indicate that this bone putty appears to be a safe biocompatible device that may be useful in the postoperative management of tooth extractions. PMID:22754572

93

Particle embolization of the bilateral superior and inferior alveolar arteries for life threatening dental socket hemorrhage.  

Particle embolization for epistaxis and intra-oral hemorrhage are performed on an as needed basis by neurointerventionalists. A case is presented of massive oral hemorrhage associated with end stage liver disease coagulopathy after tooth extraction of bilateral maxillary and mandibular molars. A man in his fifties with end stage liver disease who presented for evaluation of a syncopal episode was determined to be in hemorrhagic shock from 2 days of persistent oral bleeding after elective tooth extractions. Conservative management with multiple blood transfusion products, packing and vasoconstrictive spray was ineffective. Microcatheter angiograms of the alveolar arteries demonstrated blood and contrast pooling within the sockets of the extracted teeth. Selection of the bilateral supplying alveolar and inferior alveolar artery branches was achieved followed by polyvinyl alcohol particle embolization (250-355 ?m). Polyvinyl alcohol particle embolization of dental socket hemorrhages is technically feasible and effective. PMID:21990507

94

Octacalcium phosphate (OCP) collagen composites enhance bone healing in a dog tooth extraction socket model  

The authors have reported that a scaffold constructed of synthetic octacalcium phosphate (OCP) and porcine atelocollagen sponge (OCP/Col) enhanced bone regeneration more than sintered b-tricalcium phosphate collagen composite or sintered hydroxyapatite collagen composite with a rat calvarial defect model. To aim for clinical application, the present study investigated whether OCP/Col would enhance bone healing in a dog tooth extraction socket model. Six adult, male, beagle dogs were used. The tooth extraction socket model was made by extracting bilateral third maxillary incisors and the subsequent removal of buccal bone. Disks of OCP/Col were implanted into one side of the model and the other side was untreated. The specimens were fixed 1 or 3 months after implantation. In radiographic ana...

95

Isolation of melatonin, the pineal gland factor that lightens melanocytes  

Objective. This preclinical pilot study evaluated the systemic, radiographic, and histological responses to bone putty containing lidocaine in a canine tooth extraction model. Methods. In five beagle dogs the right mandibular premolars were extracted and sockets grafted with (1) xenograft particulate bone and a collagen sponge plug (control), (2) bone putty alone, (3) bone putty mixed with xenograft (3?:?1), or (4) xenograft sandwiched between bone putty. At 6 weeks post-op, the systemic and local responses were evaluated using a blood chemistry panel, micro-CT, and histological analyses. Results. No significant differences in blood chemistries were noted at 6 weeks postgrafting compared to baseline. Sockets grafted with either bone putty formulation demonstrated comparable radiographic and histologic evidence of bone healing compared to control sockets. Conclusions. Our preclinical results indicate that this bone putty appears to be a safe biocompatible device that may be useful in the postoperative management of tooth extractions. PMID:11268363

96

Bio Oss Collagen in the buccal gap at immediate implants: a 6 month study in the dog  

Abstract Background: Following tooth extraction and immediate implant installation, the edentulous site of the alveolar process undergoes substantial bone modeling and the ridge dimensions are reduced. Objective: The objective of the present experiment was to determine whether the process of bone modeling following tooth extraction and immediate implant placement was influenced by the placement of a xenogenic graft in the void that occurred between the implant and the walls of the fresh extraction socket. Material and methods: Five beagle dogs about 1 year old were used. The 4th premolar in both quadrants of the mandible (4P4) were selected and used as experimental sites. The premolars were hemi sected and the distal roots removed and, subsequently, implants were inserted in the distal soc...

97

Alveolar bone dimensional changes of post-extraction sockets in humans: a systematic review  

Van der Weijden F, Dell'Acqua F, Slot DE. Alveolar bone dimensional changes of post-extraction sockets in humans :a systematic review. J Clin Periodontol 2009; 36: 1048-1058. doi: 10.1111/j.1600-051X.2009.01482.x. Abstract Objective: To review the literature to assess the amount of change in height and width of the residual ridge after tooth extraction. Material and Methods: MEDLINE-PubMed and the Cochrane Central register of controlled trials (CENTRAL) were searched through up to March 2009. Appropriate studies which data reported concerning the dimensional changes in alveolar height and width after tooth extraction were included. Approximal height change, mid-buccal change, mid-crestal change, mid-lingual change, Alveolar width change and socket fill were selected as outcome variables. M...

98

Development and importance of health needs assessment  

Advances in dentistry, as well as the increased desire of patients to maintain their dentition, have led to treatment of teeth that once would have been removed. Mandibular first molars are the most commonly extracted teeth due to dental caries and periodontal disease. These teeth are the major standpoint for occlusion, and also have a wide pericemental area. Hence, any defect in the root either mesial or distal, extraction is the most common treatment planned. Under specific conditions, only the diseased part of the tooth can be extracted after an endodontic treatment. A modified fixed partial denture design is fabricated to splint the remaining portion of the tooth to adjacent teeth. This procedure though daunting can be easily achieved and maintained successfully. PMID:9554906

99

A Prospective Study of the Extraction and Retention Incidence of Endodontically Treated Teeth with Uncertain Prognosis after Endodontic Referral  

IntroductionThe present study was conducted with the aim to assess the extraction and retention incidence of endodontically treated teeth with an uncertain prognosis after endodontic referral and to evaluate the factors related to the decision-making process. MethodsTwo hundred seventy-five permanent teeth were clinically and radiographically evaluated by 3 experienced endodontists. The type of tooth, age and sex of the patients, the motive of referral, and the main chief complaint were the initial recorded data. The associations between extraction reasons and the patients' age and sex or tooth type were analyzed using the chi-square test. ResultsOf the 275 teeth examined, 217 (79%) were finally extracted. The remaining 58 (21%) teeth were endodontically retreated and restored. A questiona...

100

An easy way to apply orthodontic extraction for impacted lower third molar compressing to the inferior alveolar nerve  

Purpose: To study the results of an easy orthodontic extraction method for impacted lower third molar removal which had roots compressing to the inferior alveolar nerve (IAN). Patients and methods: Forty patients were divided into two groups according to their desire. Orthodontic traction group (n=20) had brackets or mini bone screws on the antagonist maxillary molars as anchorage for orthodontic traction from 3 to 10 weeks until the roots' tip was away from the IAN, the tooth was then removed. Traditional extraction group (n=20) had the tooth removed immediately by the same surgeon. Post-operative results were compared between the two groups. Results: All 20 patients in the orthodontic extraction group had their lower impacted third molar removed easily without lower lip numbness after su...

 
 
 
 
101

[Immediate implant placement in endodontically infected sites: an alternative treatment for compromised teeth].  

In certain clinical conditions when endodontic treatment is either impractical or unlikely to improve the previous results, tooth extraction and replacement with a dental implant becomes a viable alternative. Although the presence of active infection has long been considered a major contraindication to the insertion of implants immediately following tooth extraction, several articles assessing this treatment modality reported excellent and promising results. The aim of this literature review is to evaluate and discuss the clinical outcome of implants placed immediately following extraction in endodontically infected sockets. A Medline and EMBASE search was performed to identify articles published from 1966 to 2010 using the keywords "dental implants", "immediate implant", "extraction socket", "infected teeth", "infected site", "infected socket". No restrictions were placed regarding the study design. Only clinical articles with at least 6 months of follow-up were included. The available relevant literature concerning this topic was limited, and based on relatively low level of evidence study designs with limited follow-up periods. However, the data analysis of the selected articles showed that an immediate implant insertion in endodontically infected sites following tooth extraction and careful debridement of the socket, could be a predictable viable technique. Additional large scaled, well-designed studies are required in order to further assess the clinical applications of this treatment alternative. PMID:22471158

102

The Formation of Apical Delta of the Permanent Teeth in Dogs  

To determine the process of formation of apical delta, a histological study on the permanent teeth was carried out in dogs. A litter of 7 clinically healthy beagle dogs and 33 adult dogs (4- to 15- year-old) of 12 breeds with periodontal disease were used for the experiments. Teeth extracted from 6-,7-,8- and 9-month-old beagles were sectioned and stained with HE solution. Tooth roots obtained from adult dogs with periodontal disease were ground. Each tooth was classified into the following root types under a light microscope: Type I (no apical delta = no apical closure), II (few apical delta), IIIA (low apical delta) and IIIB (high apical delta). In the 6-month-old beagles, more than half the tooth roots were classified as type I. In the 7-month-old beagles, type IIIB apical delta was the most predominant and types I, II and IIIA apical delta were occassionally seen. Apical closure and delta were observed in all beagles at 8 months of age histologically. In the 8- and 9-month-old beagles, all root apexes observed were type IIIB. Most of the 314 tooth roots extracted from 33 adult dogs were type IIIB, but a few were type IIIA.   

103

A case of supernumerary primary and permanent canines  

A case of supernumerary primary and permanent canines is presented. A 9Y4M-old boy was referred to our clinic for consultation regarding a maxillary supernumerary primary canine. An oral examination showed 2 primary canines with a similar morphology between the maxillary left lateral incisor and first primary molar. The primary canine in the opposite quadrant had the appearance of a fused-tooth, with composite resin restoration seen in the border. Orthopantomography revealed that permanent successors were present for each primary tooth in the maxillary left region, whereas only a single permanent canine was developing in the opposite quadrant. The 2 primary canines in the maxillary left region were extracted at 9Y4M. The mesially located permanent canine emerged into the oral cavity at 10Y1M and was extracted at 10Y9M. At 12Y2M, the other permanent canine located in the distal position had nearly reached the occlusal plane and the maxillary right permanent canine had arrived at the occlusal plane. Dental age was evaluated by assessing the tooth formation stages in 4 orthopantomographs taken between 8Y5M and 12Y2M, and found to be nearly the same as chronological age. However, the dental ages of the maxillary left permanent canine that had erupted earlier than the one located distally and of the left permanent canine were approximately 1 year behind chronological age. In addition, the dental age of the left permanent canine located distally was 2.5 years behind until the patient reached the age of 10Y9M, after which tooth development was accelerated following extraction of the mesially located permanent tooth.   

104

Extracellular Glutamate Release in the Edentulous Rat Hippocampus following Tetanic Stimulation: in vivo Study by Microdialysis  

Purpose: Loss of molar teeth in rats has been reported to be associated with impairment of spatial memory, which may be related to hypo function of the hippocampus. However, the effects of tooth loss on the higher brain functions still remain unclear. In the present study, the glutamate levels in the hippocampus were measured as an index of the functions of the hippocampus, in order to elucidate the neurochemical changes in the brain in edentulous rats.Methods: At the start of this study, 4-week-old male Sprague-Dawley rats were divided into 3 groups: EXT, in which all the maxillary molar teeth were extracted; ANE, in which anesthesia was administered, but no tooth extraction was performed; UNT, in which neither anesthesia was administered nor tooth extraction was performed. A guide cannula and recording electrode were then fixed in the right hippocampus of the rats at 7 weeks of age. A dialysis probe with a stimulation electrode was introduced into the guide cannula after allowing a 1-week recovery period, and the glutamate levels in the hippocampus were measured in the rats at 8 weeks of age. Tetanic stimulation (100 pulses of 0.2-ms duration at 100 Hz) was applied to the hippocampus through the stimulation electrode undermonitoring by extracellular recording via the recording electrode when the glutamate levels had stabilized. The fluctuations in the glutamate levels following the tetanic stimulation were compared among the three experimental groups using a brain microdialysis system.Results: The extracellular glutamate concentrations within the hippocampus increased in all the 3 experimental groups following tetanic stimulation. However, the edentulous rats exhibited lower increases in the glutamate levels as compared with the sham and untreated groups.Conclusion: Decreased afferent information from periodontal sensory receptors resulting from molar tooth loss in rats appears to cause hippocampal hypofunction. Tooth loss may thus cause impairment of memory and learning in humans.   

105

Alveolar buccal bone maintenance after immediate implantation with a surgical flap approach: a study in dogs.  

This study evaluated buccal bone maintenance after implantation with a surgical flap approach immediately following tooth extraction in a dog model. Mandibular premolars of six dogs were extracted, and threaded implants of 4-mm diameter and 8-mm length with as-machined and dual acid-etched surfaces were placed through balanced procedures in the distal root extraction sockets with a full-thickness flap design. Submerged healing was allowed for 4 weeks, and following euthanization, bone-to-implant contact and buccal and lingual bone loss were evaluated. None of the parameters evaluated were indicative of an effect of implant surface in hindering bone loss around immediately placed implants. PMID:22140672

106

[Frequency of tooth removal because of orthodontic reasons].  

In certain orthodontic treatments therapy includes the removal of permanent tooth or teeth. The number of objective studies on assessing extraction frequency is low and values in the international publications range between wide limits. This shows that often the extraction decision in the treatment planning does is not made upon the criteria of evidence-based dentistry. In our practice, a retrospective analysis of treatment plans prepared between the 1st of January 2004 and the 31st of December 2006 (416 cases) has been performed. The overall prevalence of treatments with extraction was 41.59% for all patients, the rate was 51.63% in patients with permanent dentition at the time of the planning. The highest proportion of extraction (49.71%) was found in Class II subdivision 2 cases, and the lowest percentage (30.17%) in Class I cases. The decision for extraction does not seem to be influenced by cephalometric analysis directly. The higher percentage of extraction found in permanent dentition period shows that when we cannot use interceptive treatment alternatives, we are forced to extract tooth more frequently. On the other hand, the lower value in early mixed dentition period can be explained by the relatively higher number of treatments with the aim to avoid extraction. PMID:19260623

107

Characterization of the lipoxygenases in some olive cultivars and determination of their role in volatile compounds formation  

Background and Purpose. Dry socket syndrome is one of the most irritating complications after tooth extraction. This study aims to investigate the efficacy of pastille GECB compared to ZOE. Materials and Methods. 30 patients with dry socket syndrome were selected and divided into two groups. GECB pastille was produced with 3% Guaiacol, 3% Eugenol 1.6% Chlorobutanol, sized 3 × 7 × 10?mm. GECB was applied in one group, and ZOE was used for the other group. Duration of pain after treatment and painkiller intake values were recorded within 20 days. The data were analyzed with independent samples t-test, Mann-Whitney, and Chi-Square tests. Results. Pain persisted for 45.53 ± 33.34 minutes in patients treated with ZOE and 19.87 ± 21.80 minutes in those treated with GECB (P = 0.19). Patients in the ZOE group reported more painkiller intake within 20 days (P = 0.031). Conclusion. GECB showed more significant efficacy in reducing complications after tooth extraction. PMID:11829653

108

Socket grafting with the use of autologous bone: an experimental study in the dog  

Abstract Background: Studies in humans and animals have shown that following tooth removal (loss), the alveolar ridge becomes markedly reduced. Attempts made to counteract such ridge diminution by installing implants in the fresh extraction sockets were not successful, while socket grafting with anorganic bovine bone mineral prevented ridge contraction. Aim: To examine whether grafting of the alveolar socket with the use of chips of autologous bone may allow ridge preservation following tooth extraction. Methods: In five beagle dogs, the distal roots of the third and fourth mandibular premolars were removed. The sockets in the right or the left jaw quadrant were grafted with either anorganic bovine bone or with chips of autologous bone harvested from the buccal bone plate. After 3 months o...

109

Measurement of ridge alterations following tooth removal: a radiographic study in humans  

Abstract Objective: The aim of this study was a radiographic mesiodistal analysis of the shape of the bone crest 3 months after tooth removal. Material and methods: One hundred single tooth extractions were performed on 100 patients because of orthodontic or prosthetic causes. Bite blocks were used for two radiographs: one on the day of extraction and the other after healing of the socket, 3 months later. These X-rays were used to determine: (1) the most apical distance of alveolar ridge resorption, with baseline as the line between bone-to-teeth contact (the greatest distance in bone resorption height) and (2) the mesiodistal distance (MDD) and mesial and distal angles arising after bone tissue modeling. Results: Significant differences (P<0.05) emerged between the MDDs of multiple- [8 mm...

110

Effect of socket preservation therapies following tooth extraction in non-molar regions in humans: a systematic review  

Abstract Objective: To assess, based on the existing literature, the benefit of socket preservation therapies in patients with a tooth extraction in the anterior or premolar region as compared with no additional treatment with respect to bone level. Material and methods: MEDLINE-PubMed and the Cochrane Central Register of controlled trials (CENTRAL) were searched till June 2010 for appropriate studies, which reported data concerning the dimensional changes in alveolar height and width after tooth extraction with or without additional treatment like bonefillers, collagen, growth factors or membranes. Results: Independent screening of the titles and abstracts of 1918 MEDLINE-PubMed and 163 Cochrane papers resulted in nine publications that met the eligibility criteria. In natural healing aft...

111

Immediate, non-submerged, root-analogue zirconia implants placed into single-rooted extraction sockets: 2-year follow-up of a clinical study  

This study evaluated non-submerged, root-analogue zirconia implants with two different surfaces for immediate single-rooted tooth replacement in 18 patients. After tooth extraction the root was laser scanned and one-piece root analogue zirconia dental implants with one of two different surfaces were manufactured. In group A (n=6) the implant surface was roughened by sandblasting only, in group B (n=12) additional macroretentions limited to the interdental space, to avoid fracture of the thin buccal cortex, were designed prior to laser scanning. Implants were placed in the socket 1-8 days after extraction by tapping and restored with a composite crown 3-5 months later. Implant survival, level of marginal bone and adverse soft tissue changes were recorded. No complications occurred during th...

112

A residual granuloma in association with a dental implant.  

At times, dental implants are placed into sites with a history of periapical pathology. Sometimes the infection is active, and other times the tooth may have been extracted years before implant placement. In either case, the possibility exists for long-term residual cysts or infections that can negatively impact the prognosis of the implant. In this case report, an implant is placed into a healed mandibular ridge several months after extraction of the tooth. A radiolucency was noted on routine radiographic examination 2 years later. Surgical inspection and histology revealed a periapical granuloma with acute and chronic inflammatory cells. After surgical curettage of the site, the patient healed without complication. Implants may develop apical pathology as a result of a preexisting long-term residual infection. PMID:22382756

113

Delayed removal of a maxillary third molar from the infratemporal fossa.  

Removal of an impacted superior third molar is usually a simple and uncomplicated procedure for an Oral and Maxillofacial Surgeon. Nevertheless, complications are possible and include infection, facial swallowing, trismus, wound dehiscence, root fracture or even orosinusal fistula. Iatrogenic displacement into the infratemporal fossa is frequently mentioned but rarely reported. This anatomical fossa includes several important structures such as the internal maxillary artery, the venous pterygoid plexus, the sphenopalatine nerve, the coronoid process of the mandible and the pterygoid muscles. Recommended treatment includes immediate surgical removal if possible or initial observation and secondary removal, as necessary, because of infection, limited mandibular movement, inability to extract the tooth, or the patient's psychological unease. Sometimes, the displaced tooth may spontaneously migrate inferiorly and becomes accessible intraorally. This report describes the location and secondary surgical removal of a left maxillary third molar displaced into the infratemporal fossa, two weeks after first attempt at extraction. PMID:20038889

114

Effect of low-level laser therapy on the healing process after tooth replantation: a histomorphometrical and immunohistochemical analysis  

Abstract--- Success of tooth replantation is limited because part of the replanted tooth is lost because of progressive root resorption. This study used histomorphometry and immunohistochemistry to evaluate the effect of low-level laser therapy (LLLT) on the healing process of rat teeth replanted after different extra-oral periods, simulating immediate and delayed replantation. Sixty Wistar rats (Rattus norvegicus albinus) had their maxillary right incisors extracted and randomly assigned to six groups (n-=-10): C4, C30 and C45, in which the teeth were replanted 4-min (immediate), 30-min (delayed) and 45-min (delayed) after extraction, respectively, and L4, L30 and L45, in which the teeth were replanted after the same extra-alveolar times, but the root surfaces and the alveolar wounds were...

115

Alveolar ridge preservation with guided bone regeneration and a synthetic bone substitute or a bovine-derived xenograft: a randomized, controlled clinical trial  

Abstract Objectives: The aim of this randomized, controlled clinical trial was to compare the potential of a synthetic bone substitute or a bovine-derived xenograft combined with a collagen membrane to preserve the alveolar ridge dimensions following tooth extraction. Methods: Twenty-seven patients were randomized into two treatment groups following single tooth extraction in the incisor, canine and premolar area. In the test group, the alveolar socket was grafted with Straumann Bone Ceramic (SBC), while in the control group, Bio-Oss deproteinized bovine bone mineral (DBBM) was applied. In both groups, a collagen barrier was used to cover the grafting material. Complete soft tissue coverage of the barriers was not achieved. After 8 months, during re-entry procedures and before implant plac...

116

Short-term vs long-term calcium hydroxide therapy after immediate tooth replantation: a histomorphometric study in monkey-s teeth  

Abstract--- Endodontic treatment is an important step of tooth replantation protocols, but the ideal moment for definitive obturation of replanted teeth has not yet been established. In this study, a histomorphometric analysis was undertaken to evaluate the repair process on immediate replantation of monkey-s teeth after calcium hydroxide (CH) therapy for 1 and 6-months followed by root canal filling with a CH-based sealer (Sealapex). The maxillary and mandibular lateral incisors of five female Cebus apella monkeys were extracted, kept in sterile saline for 15-min, replanted and splinted with stainless steel orthodontic wire and composite resin for 10-days. In Group I (control), definitive root canal filling was performed before tooth extraction. In Groups II and III, CH therapy started af...

117

Care of oral cavity in irradiated patients  

Procedures are reviewed of therapeutic and preventive care in patients with malignant tumours in the area of the head and neck during radiotherapy and during the subsequent follow-up of patients. As compared with previous views, the care is now more conservative, indications for tooth extractions are now limited, careful oral hygiene is emphasized and, in particular, the long-term use of fluorine gel is recommended. Surgery is only recommended where conservative treatment fails.

118

Histologic and histomorphometric assessment of implants and periapical tissues when placed in the sockets of extracted teeth, teeth with periapical lesions and healed lesions: A canine study.  

Abstract Eighteen canine mandibular premolars were divided into three groups. In Group 1: Implants were inserted in periapical lesions. In Group 2: Implants were inserted when lesions were radiographically healed. In Group 3 (Control):Implants were inserted immediately after extraction. There was no significant difference in average bone implant contact between the three groups. Considering the limitations of this study, immediate placement of dental implants in tooth sockets with periapical lesions should be proposed only under special circumstances. PMID:22103780

119

Stress analysis of occlusal forces in canine teeth and their role in the development of non-carious cervical lesions: abfraction.  

Non-carious cervical tooth lesions for many decades were attributed to the effects of abrasion and erosion mainly through toothbrush trauma, abrasive toothpaste, and erosive acids. However, though the above may be involved, more recently a biomechanical theory for the formation of these lesions has arisen, and the term abfraction was coined. The aim of this study was to investigate the biomechanics of abfraction lesions in upper canine teeth under axial and lateral loading conditions using a three-dimensional finite element analysis. An extracted human upper canine tooth was scanned by ?CT machine (Skyscan, Belgium). These ?CT scans were segmented, reconstructed, and meshed using ScanIP (Simpleware, Exeter, UK) to create a three-dimensional finite element model. A 100?N load was applied axially at the incisal edge and laterally at 45° midpalatally to the long axis of the canine tooth. Separately, 200?N axial and non-axial loads were applied simultaneously to the tooth. It was found that stresses were concentrated at the CEJ in all scenarios. Lateral loading produced maximum stresses greater than axial loading, and pulp tissues, however, experienced minimum levels of stresses. This study has contributed towards the understanding of the aetiology of non-carious cervical lesions which is a key in their clinical management. PMID:22919387

120

A comparison between adipose tissue and dental pulp as sources of MSCs for tooth regeneration.  

In this study, several in vivo and in vitro comparisons were performed to test the possibility of using adipose-derived stem cells (ADSCs), a more convenient cell source than dental pulp stem cells (DPSCs), in tooth regeneration. Using an efficient, non-engineering implantation method, we first demonstrated that both implants of ADSCs and DPSCs were able to grow self-assembled new teeth in adult rabbit extraction sockets with high success rate. The stem cells were necessary because the implants grew no tooth without them. A stepwise comparison showed that the regenerated teeth from these two types of adult stem cells were living with nerves and vascular system and remarkably similar to a normal tooth in many details. Further strictly controlled, side-by-side comparisons between the two types of stem cells also showed that the expression patterns of gene markers and the broad differentiation potentials induced by specific methods in vitro were very similar. Although a few differences were found, they did not affect the tested tooth regeneration in vivo or differentiation in vitro. Furthermore, rabbit ADSCs had a higher growth rate and a better senescence resistance in culture. All these findings suggest that ADSCs, one of the richest adult stem cells in mammals, are very similar and useful as DPSCs for regenerative dentistry. PMID:21696818

 
 
 
 
121

Biomechanical effects of splint types on traumatized tooth: a photoelastic stress analysis.  

This study was undertaken to assess the effect of splint type on stresses occurring around traumatized tooth by photoelastic stress analysis. Three semi-rigid splint types--a wire-composite splint, fiberglass splint and titanium trauma splint--were utilized for comparisons. Extracted left upper central and lateral incisors and the canine tooth of an otherwise healthy patient were embedded equidistantly in photoelastic resin. For all cases studied, a static axial and 20 degrees oblique force of 100 N was applied on the lateral incisor in separate sessions. The experiments were undertaken without any splint application (unsplinted, control) after which the splints, adhesively bonded to the labial aspects of teeth, were consecutively tested. During each loading sequence, generation of isochromatic fringes was observed in the field of a polariscope, and photographed by a digital camera. Quantification of fringes was performed on magnified images, transferred to a PC. Under vertical loading, the highest stresses in the apical regions were observed for the unsplinted and ribbond-splint groups, whereas the lowest fringes occurred with the use of orthodontic wire as a splinting medium. Titanium trauma splint had absolutely no effect on reduction of stresses, as the fringe orders were slightly higher than the unsplinted lateral tooth. The use of orthodontic wire resulted in lowest fringe orders around the traumatized tooth. PMID:16643288

122

Premature loss of maxillary primary incisor and delayed eruption of its successor: report of a case.  

BACKGROUND: Traumatic injuries to primary teeth represent one of the most common aetiologic factors of time-related eruption disturbances of permanent teeth. These include premature eruption, delayed eruption or impactions. CASE REPORT: A case of a 7.5-year-old male with delayed eruption of the maxillary permanent left incisor is presented. The case history revealed a trauma around the age of 3 involving its primary tooth predecessor and its extraction by a dentist about one year later due to frequent abscesses. The clinical examination showed an early mixed dentition and the single presence of tooth 11 in the dental arch, with an obvious aesthetic problem that affected the child's self image. The periapical x-ray ruled out any dimorphism on the impacted tooth, and it showed a root developed by two thirds. About 2 months after the examination, a simple gingivectomy was carried out, and the tooth could erupt completely 3 months later without any need for orthodontic traction. One year after surgery, a complete root development could be observed, as well as the presence of the lateral incisors with a moderate crowding. PMID:22077690

123

Biophysical dose measurement using electron paramagnetic resonance in rodent teeth  

Electron paramagnetic resonance (EPR) dosimetry of human tooth enamel has been widely used in measuring radiation doses in various scenarios. However, there are situations that do not involve a human victim (e.g. tests for suspected environmental overexposures, measurements of doses to experimental animals in radiation biology research, or chronology of archaeological deposits). For such cases we have developed an EPR dosimetry technique making use of enamel of teeth extracted from mice. Tooth enamel from both previously irradiated and unirradiated mice was extracted and cleaned by processing in supersaturated KOH aqueous solution. Teeth from mice with no previous irradiation history exhibited a linear EPR response to the dose in the range from 0.8 to 5.5 Gy. The EPR dose reconstruction for a preliminarily irradiated batch resulted in the radiation dose of (1.4{+-}0.2) Gy, which was in a good agreement with the estimated exposure of the teeth. The sensitivity of the EPR response of mouse enamel to gamma radiation was found to be half of that of human tooth enamel. The dosimetric EPR signal of mouse enamel is stable up at least to 42 days after exposure to radiation. Dose reconstruction was only possible with the enamel extracted from molars and premolars and could not be performed with incisors. Electron micrographs showed structural variations in the incisor enamel, possibly explaining the large interfering signal in the non-molar teeth.

124

An experimental study of extraction wound healing in the calcium deficient rat and maxillofacial  

The purpose of this study was to investigate effects of osteoporosis on extraction wound healing in the calcium deficient rat. In order to carry out this study, ten-week old Wistar strain rats weighing about 300 gms were selected. When the ras reached thirteen-week old, rat's mandibular first molar were removed. The rats were then divided into three groups : Group 1(rats given a normal diet both before and after tooth extraction), Group 2(rats given a low calcium diet for three weeks before tooth extraction and a normal diet after tooth extraction), and Group 3(rats given a low calcium diet for three weeks before and after tooth extraction). The healing of extraction wounds, as assessed by microradiography, autoradiography, and histopathologic examination, were compared among these three groups. The obtained results were as follows : 1. In Group 1, newly formed bone and active uptake of 45 Ca around extraction wound were noted on the 3rd and the 7th day. On the 14th and the 21st day, the extraction wounds of this group showed the bone trabecular formation and active 45 Ca uptake in the extraction wound and alveolar crest. The more prominent bone trabuculae with a less uptake of 45 Ca were noted on the 42nd day. 2. In Group 2, newly formed bone and thinning of alveolar bone trabeculae with more extensive uptake of 45 Ca than that in Group 1 were noted on the 3rd and the 7th day. On the 14th day, bone trabeculae were less thicker than that in Group 1. the prominent bone trabeculae in the extraction wounds and alveolar crest were noted on the 21st and the 42nd days. 3. In Group 3, newly formed bone was noted on the 3rd and the 7th day, Alveolar bone trabeculae and uptake of 45 Ca were similar to that in Group 2. On the 14th and 21st day, bone trabeculae were less thicker than that in Group 2 and group 3. the osteoporotic change with active uptake of 45 Ca was markedly noted on the 42nd day.

125

A review on alveolar ridge preservation following tooth extraction.  

Context The question that clinicians face is whether the use of bone replacement grafts and/or barrier membranes enhance their ability to provide for the future placement of a dental implant or to maximize ridge dimensions following the extraction of a tooth versus no additional treatments. Evidence Acquisition The evidence was obtained by search of Entrez PubMed and manual search of The International Journal of Oral and Maxillofacial Implants, The International Journal of Periodontics & Restorative Dentistry, Clinical Oral Implant Research, The Journal of Periodontology, The Journal of Clinical Periodontology, and The Compendium of Continuing Education in Dentistry. Key search words included Guided Bone Regeneration, Dental Extraction, Tooth Extraction, Bone Replacement Graft, Alveolar Ridge. The years of search included from January 2011 through February 2012. Evidence Synthesis The recurring theme was that there was considerable heterogeneity to study designs, time periods, and methods of evaluation. This created great difficulty in trying to answer with good high-quality evidence questions about the techniques and materials to be used for maximizing regeneration at the time of tooth extraction or in which situations this ought to be used. Conclusions There appears to be consensus from the reviewed literature supporting ridge preservation techniques as a whole. Multiple studies demonstrated less ridge resorption occurring when alveolar ridge preservation procedures were used versus the placement of no graft material in fresh alveolar sockets. The analysis did not show any grafting materials demonstrating a clear benefit over any others or that a barrier membrane is necessary. The evidence is also too premature about whether socket preservation efforts require primary closure. In the emerging area of growth factors, there is no high-quality evidence to either support or refute their use. Background Tooth extraction is one of the most widely performed procedures in dentistry today and it has been historically well documented that this procedure may induce significant dimensional changes of the alveolar ridge. The dilemma that clinicians face is how to manage tooth extractions to provide for the future placement of a dental implant or to maximize ridge dimensions for the fabrication of a fixed or removable prosthesis. If performed inadequately, the resulting deformity can be a considerable obstacle to the esthetic, phonetic, and functional results that both our patients and we clinicians expect at this current time. PMID:23040345

126

Automating digital leaf measurement: the tooth, the whole tooth, and nothing but the tooth.  

Many species of plants produce leaves with distinct teeth around their margins. The presence and nature of these teeth can often help botanists to identify species. Moreover, it has long been known that more species native to colder regions have teeth than species native to warmer regions. It has therefore been suggested that fossilized remains of leaves can be used as a proxy for ancient climate reconstruction. Similar studies on living plants can help our understanding of the relationships. The required analysis of leaves typically involves considerable manual effort, which in practice limits the number of leaves that are analyzed, potentially reducing the power of the results. In this work, we describe a novel algorithm to automate the marginal tooth analysis of leaves found in digital images. We demonstrate our methods on a large set of images of whole herbarium specimens collected from Tilia trees (also known as lime, linden or basswood). We chose the genus Tilia as its constituent species have toothed leaves of varied size and shape. In a previous study we extracted c.1600 leaves automatically from a set of c.1100 images. Our new algorithm locates teeth on the margins of such leaves and extracts features such as each tooth's area, perimeter and internal angles, as well as counting them. We evaluate an implementation of our algorithm's performance against a manually analyzed subset of the images. We found that the algorithm achieves an accuracy of 85% for counting teeth and 75% for estimating tooth area. We also demonstrate that the automatically extracted features are sufficient to identify different species of Tilia using a simple linear discriminant analysis, and that the features relating to teeth are the most useful. PMID:22870286

127

Retrospective biodosimetry with small tooth enamel samples using K-Band and X-Band  

In an attempt to make the in vitro electron spin resonance (ESR) retrospective dosimetry of the tooth enamel a lesser invasive method, experiments using X-Band and K-Band were performed, aiming to determine conditions that could be used in cases of accidental exposures. First, a small prism from the enamel was removed and ground with an agate mortar and pestle until particles reach a diameter of approximately less than 0.5 mm. This enamel extraction process resulted in lower signal artifact compared with the direct enamel extraction performed with a diamond burr abrasion. The manual grinding of the enamel does not lead to any induced ESR signal artifact, whereas the use of a diamond burr at low speed produces a signal artifact equivalent to the dosimetric signal induced by a dose of 500 mGy of gamma irradiation. A mass of 25 mg of enamel was removed from a sound molar tooth previously irradiated in vitro with a dose of 100 mGy. This amount of enamel was enough to detect the dosimetric signal in a standard X-Band spectrometer. However using a K-Band spectrometer, samples mass between 5 and 10 mg were sufficient to obtain the same sensitivity. An overall evaluation of the uncertainties involved in the process in this and other dosimetric assessments performed at our laboratory indicates that it is possible at K-Band to estimate a 100 mGy dose with 25% accuracy. In addition, the use of K-Band also presented higher sensitivity and allowed the use of smaller sample mass in comparison with X-Band. Finally, the restoration process performed on a tooth after extraction of the 25 mg of enamel is described. This was conducted by dental treatment using photopolymerizable resin which enabled complete recovery of the tooth from the functional and aesthetic viewpoint showing that this procedure can be minimally invasive.

128

Multi-lobed mesiodens with a palatal talon cusp: a rare case report  

Abstract in portuguese Mesiodens é um dente supranumerário mais comumente visto no arco maxilar na linha média, e a cúspide em garra (talon cusp) é uma anomalia dental de desenvolvimento rara que ocorre na face lingual de dentes anteriores. Este artigo apresenta um caso clínico raro de desenvolvimento de uma cúspide em garra em um mesiodens multilobulado que causava interferência tanto na oclusão quanto na aparência de um paciente de 11 anos de idade. Durante a entrevista clínica, o (more) paciente relatou dificuldade na mastigação. Exame clínico e radiográfico revelou que um dente supranumerário com raiz completamente formada estava causando interferência oclusal. O dente supranumerário foi diagnosticado como sendo um mesiodens multilobulado associado a uma cúspide em garra palatina. O plano tratamento consistiu na extração do dente supranumerário seguida de tratamento ortodôntico para fechamento de diastema e alinhamento dos dentes. Abstract in english Mesiodens is a midline supernumerary tooth commonly seen in the maxillary arch and the talon cusp is a rare dental developmental anomaly seen on the lingual surface of anterior teeth. This paper presents a rare clinical case of development of talon cusp in a mesiodens with multiple lobes, which interfered with both occlusion and appearance of an 11-year-old patient. During clinical interview, the patient reported difficulty on mastication. Clinical and radiographic examin (more) ation revealed that a supernumerary tooth with completely formed root was causing an occlusal interference. The supernumerary tooth was diagnosed as multi-lobed mesiodens associated with a palatal talon cusp. The treatment plan consisted in the extraction of the supernumerary tooth followed by orthodontic treatment for diastema closure and tooth alignment.

129

A Systematic Review of the Clinical Performance of Tooth-Retained and Implant-Retained Double Crown Prostheses with a Follow-Up of ?3 Years.  

Purpose: The objective of this review was to systematically screen the literature for data related to the survival and complication rates observed with dental or implant double crown abutments and removable prostheses under functional loading for at least 3 years. Materials and Methods: A systematic review of the dental literature from January 1966 to December 2009 was performed in electronic databases (PubMed and Embase) as well as by an extensive hand search to investigate the clinical outcomes of double crown reconstructions. Results: From the total of 2412 titles retrieved from the search, 65 were selected for full-text review. Subsequently, 17 papers were included for data extraction. An estimation of the cumulative survival and complication rates was not feasible due to the lack of detailed information. Tooth survival rates for telescopic abutment teeth ranged from 82.5% to 96.5% after an observation period of 3.4 to 6 years, and for tooth-supported double crown retained dentures from 66.7% to 98.6% after an observation period of 6 to 10 years. The survival rates of implants were between 97.9% and 100% and for telescopic-retained removable dental prostheses with two mandibular implants, 100% after 3.0 and 10.4 years. The major biological complications affecting the tooth abutments were gingival inflammation, periodontal disease, and caries. The most frequent technical complications were loss of cementation and loss of facings. Conclusions: The main findings of this review are: (I) double crown tooth abutments and dentures demonstrated a wide range of survival rates. (II) Implant-supported mandibular overdentures demonstrated a favorable long-term prognosis. (III) A greater need for prosthetic maintenance is required for both tooth-supported and implant-supported reconstructions. (IV) Future areas of research would involve designing appropriate longitudinal studies for comparisons of survival and complication rates of different reconstruction designs. PMID:22947104

130

Prevalence of Dental Anomalies in Patients with Nonsyndromic Cleft Lip and/or Palate in a Brazilian Population.  

Abstract Objective: Many studies have demonstrated a high frequency of dental anomalies in patients with cleft lip and/or palate (CL/P). Since dental anomalies may complicate dental treatment, we investigated the prevalence of dental anomalies in a group of Brazilian patients with nonsyndromic CL/P (NSCL/P). Design, Participants, Setting: Retrospective analysis was performed using clinical records of 296 patients with repaired NSCL/P aged between 12 and 30 years without history of tooth extraction and orthodontic treatment. Associations between oral clefts and presence of dental anomalies outside the cleft area were investigated. Results: Dental anomalies were identified in 39.9% of the NSCL/P patients, and tooth agenesis (47.5%), impacted tooth (13.1%) and microdontia (12.7%) were the most common anomalies. CL patients were less affected by dental anomalies compared with CP or CLP patients (p=0.057). Specifically, unilateral CLP patients were significantly more affected by dental anomalies than bilateral CLP patients (p=0.00002), and individuals with unilateral complete CLP (p=0.002) and complete CP (p=0.01) were significantly more affected by tooth agenesis than other cleft types. Ageneses of the premolars (p=0.043) and maxillary lateral incisors (p=0.03) were significantly more frequent in unilateral complete CLP patients. Conclusions: The present study revealed a high frequency of dental anomalies in NSCL/P patients, and further demonstrated that patients with unilateral CLP were frequently more affected by dental anomalies than bilateral CLP. Moreover, our results demonstrate that dental anomalies should be considered during dental treatment planning of individuals affected by NSCL/P. Keywords: Cleft lip and palate; dental anomaly; tooth agenesis; dental treatment. PMID:21973329

131

Restoration of the upper dental arch using Lava all-ceramic crown and bridgework  

PURPOSE Many dentists use desensitizing agents to prevent hypersensitivity. This study compared and evaluated the effect of two desensitizing agents on the retention of cast crowns when cemented with various luting agents. MATERIALS AND METHODS Ninety freshly extracted human molars were prepared with flat occlusal surface, 6 degree taper and approximately 4 mm axial length. The prepared specimens were divided into 3 groups and each group is further divided into 3 subgroups. Desensitizing agents used were GC Tooth Mousse and GLUMA® desensitizer. Cementing agents used were zinc phosphate, glass ionomer and resin modified glass ionomer cement. Individual crowns with loop were made from base metal alloy. Desensitizing agents were applied before cementation of crowns except for control group. Under tensional force the crowns were removed using an automated universal testing machine. Statistical analysis included one-way ANOVA followed by Turkey-Kramer post hoc test at a preset alpha of 0.05. RESULTS Resin modified glass ionomer cement exhibited the highest retentive strength and all dentin treatments resulted in significantly different retentive values (In Kg.): GLUMA (49.02 ± 3.32) > Control (48.61 ± 3.54) > Tooth mousse (48.34 ± 2.94). Retentive strength for glass ionomer cement were GLUMA (41.14 ± 2.42) > Tooth mousse (40.32 ± 3.89) > Control (39.09 ± 2.80). For zinc phosphate cement the retentive strength were lowest GLUMA (27.92 ± 3.20) > Control (27.69 ± 3.39) > Tooth mousse (25.27 ± 4.60). CONCLUSION The use of GLUMA® desensitizer has no effect on crown retention. GC Tooth Mousse does not affect the retentive ability of glass ionomer and resin modified glass ionomer cement, but it decreases the retentive ability of zinc phosphate cement. PMID:17589454

132

Autogenous Transplantation of Maxillary and Mandibular Molars  

Purpose Autogenous tooth transplantation has been used as a predictable surgical approach to correct malocclusion and replace edentulous areas. This article focuses on the surgical approach and technique for molar transplantation. Patients and Methods Thirty-two patients aged between 11 and 25 years underwent 44 autogenous molar transplantations. The procedure involved transplantation of impacted or newly erupted third molars into the extraction sockets of nonrestorable molars and surgical removal and replacement of horizontally impacted molars into their proper vertical alignment. Five basic procedural concepts were applied: 1) atraumatic extraction, avoiding disruption of the root sheath and root buds; 2) apical contouring of bone at the transplantation site and maxillary sinus lift via ...

133

Morphological Features of Peri-Implant Tissue after Placement of Dental Implants into the Extraction Socket  

In experiments on pigs, bone regeneration was studied after implantation of implants with four cylindrical roots and support cone and laminar crest-shaped implants with shape memory effect. The implants were placed to the extraction socket (mandibular canine) and through the socket immediately after tooth extraction using osteoplastic material or without using collapan-L. The use of collapan-L accelerated regeneration of peri-implant tissue and provided stable fixation of dental construct in the bone over 3?months after surgery, which can be relevant for determining timing of prosthodontic therapy and constructional features of prosthesis.

134

The dual-zone therapeutic concept of managing immediate implant placement and provisional restoration in anterior extraction sockets.  

Improvements in implant designs have helped advance successful immediate anterior implant placement into fresh extraction sockets. Clinical techniques described in this case enable practitioners to achieve predictable esthetic success using a method that limits the amount of buccal contour change of the extraction site ridge and potentially enhances the thickness of the peri-implant soft tissues coronal to the implant-abutment interface. This approach involves atraumatic tooth removal without flap elevation, and placing a bone graft into the residual gap around an immediate fresh-socket anterior implant with a screw-retained provisional restoration acting as a prosthetic socket seal device. PMID:22908601

135

WITHDRAWN: Immediate Placement and Provisionalization of Implant-Supported, Single-Tooth Restorations: A Retrospective Study.  

Abstract Immediate implant placement into extraction sockets has been widely reported in the dental literature, but few studies have evaluated the immediate loading of such implants. In this retrospective study, we evaluated 235 implants placed into fresh extraction sites utilizing a flapless technique, followed by immediate provisionalization with non-functional single-tooth restorations, and definitive restoration within 2 weeks. Cumulative survival and success rates were 98.8% (mean follow-up = 23.1 months). Periodontitis did not adversely influence the outcome. Within the limitations of this study, immediate implant placement and restoration followed by definitive loading within 2 weeks achieved outcomes comparable to those historically reported for delayed implants. PMID:21905899

136

Il trattamento chirurgico di elementi dentari soprannumerari: tre casi di quarti molari  

Objectives: To review the diagnosis, causes, treatment, and possible complications of impacted supernumerary fourth molars on the basis of data reported in the literature and our own clinical experience. Materials and methods: We report three cases of supernumerary fourth molars that were treated by surgical extraction. Results and conclusions: None of the patients who underwent surgery experienced intraoperative- or postoperative complications. Surgical extraction of the supernumerary tooth eliminates the risk of complications such as root resorption involving adjacent teeth, delayed eruption of permanent teeth, dental crowding, and the development of odontogenic cysts.

137

Logistic Regression Analysis of Risk Factors for the Development of Alveolar Osteitis  

Purpose To assess risk factors for alveolar osteitis. Materials and Methods A prospective nested case-control study was conducted in an urban community dental clinic in Valdivia, Chile. A cohort of 1,355 patients who underwent dental extractions was included. Eight predictor variables (risk factors), namely patient gender, hygiene, tooth location, previous surgical site infection, traumatic extraction, systemic diseases, alcohol consumption, and tobacco use, were considered in a risk factor model. A binary regression logistic analysis was performed to determine significant associations. Results In total 1,302 participants completed the follow-up. Eighty incident case patients with alveolar osteitis and 80 matched control patients were included. A statistically significant association was f...

138

The effect of posterior tooth loss on the expression of type II collagen, IL-1@b and VEGF in the condylar cartilage of growing rats  

Objective: The aim of this study was to evaluate the effect of unilateral and bilateral loss of posterior occlusal support on the expression of type II collagen, interleukin-1@b and VEGF in the condylar cartilage of growing rats. Design: Thirty female Wistar rats (5 weeks old) were randomized into three groups: control, unilateral extraction of mandibular molar teeth, bilateral extraction of mandibular molar teeth. Animals were sacrificed 8 weeks after tooth extraction and the temporomandibular joints were prepared for immunohistochemical analysis. Results: Bilateral molar extraction increased the expression of interleukin-1@b (P<0.01) and VEGF (P<0.01), while unilateral extraction increased the expression of interleukin-1@b (P<0.05) and type II collagen (P<0.01). The expression of VEGF wa...

139

Evaluation of the Hemostatic Effects of Ankaferd Blood Stopper During Dental Extractions in Patients on Antithrombotic Therapy.  

This study evaluated the early hemostatic effects of a novel hemostatic agent (Ankaferd blood stopper [ABS]) during dental extractions in patients on antithrombotic therapy, without interruption or diminution of the medication. In total, 25 patients, who are on antithrombotic therapy and in need of simple dental extractions, were randomized into 2 groups. In group I (control group), which consisted of 10 patients, local hemostasis was achieved with direct packing with gauze. In group II, which consisted of 15 patients, local hemostasis was achieved by the local application of ABS on the extraction sockets. The bleeding time was compared between 2 groups following the tooth extraction. The bleeding time in the dental sockets treated with ABS was statistically lower compared to the sockets of the control group (p = 0.0001). It is concluded that the dental extractions could be performed without interruption of the medication in patients on antithrombotic therapy. The ABS appears to be sufficient as an alternative hemostatic agent. PMID:22327817

140

Osteogenesis imperfecta  

Background: Socket preservation after tooth extraction is one of the indications of bone grafting to enhance preorthodontic condition. The aim of this study is to determine the effects of socket preservation on the immediate tooth movement, alveolar ridge height preservation and orthodontic root resorption. Materials and Methods: In a split-mouth technique, twelve sites in three dogs were investigated as an experimental study. Crushed demineralized freeze-dried bone allograft (DFDBA) (CenoBone®) was used as the graft material. The defects were made by the extraction of 3rd premolar. On one side of each jaw, the defects were preserved by DFDBA and defects of the other side left opened as the control group. Simultaneously the teeth adjacent to the defects were pulled together by a NiTi coil spring. After eight weeks, the amount of (OTM), alveolar height, and root resorption were measured. Analysis of variance was used for purpose of comparison. Results: There was a slight increase in OTM at grafted sites as they were compared to the control sites (Psocket preservation in experimental site were observed. Reduction of root resorption at the augmented site was significant compared to the normal healing site (Psocket preservation, tooth movement can be immediately started without waiting for the healing of the recipient site. This can provide some advantages like enhanced rate of OTM, its approved effects on ridge preservation that reduces the chance of dehiscence and the reduction of root resorption. PMID:19753756

 
 
 
 
141

Impacted teeth in the maxilla: usefulness of 3D Dental-CT for preoperative evaluation  

Objective: To compare the shapes of roots of impacted teeth shown in three-dimensional computed tomographic images (3D Dental-computed tomography (CT) images) and plain radiographs and to determine whether 3D Dental-CT images are useful for examination before performing an operation for extraction of a maxillary impacted tooth. Methods and patients: Images obtained from patients who had impacted teeth in the maxilla, including impacted mesial supernumerary teeth in 13 patients, impacted incisors in two patients, impacted canines in 11 patients, impacted premolars in four patients and impacted molars in three patients, were used in this study. In all patients, plain radiographs and 3D Dental-CT images were retrospectively reviewed by an oral radiologist for evidence of root dilaceration before operations to extract the impacted teeth were performed. The findings in the images were compared with intraoperative findings in all cases. Results: The mean specificity and sensitivity of plain radiographs were 95 and 8%, respectively, while those of 3D Dental-CT images were 100 and 77%, respectively. There was a statistically significant (P<0.01) difference between the depiction capabilities of plain radiographs and 3D Dental-CT images with regard to dilacerations of roots of impacted teeth. Discussion and conclusion: CT may enable radiologists to make a quick and accurate diagnosis of tooth impaction. 3D Dental-CT images are useful for determining the root shape of an impacted tooth in the maxilla.

142

Hippocampal Glutamate Release on Learning and Memory in Teeth-loss Rats  

Purpose: To clarify the effects of molar tooth loss on learning and memory, hippocampal glutamate release during a passive-avoidance task was measured with a telemetric glutamate biosensor.Methods: Male Sprague-Dawley rats were used. Under general anesthesia, all the maxillary molars were extracted from the EXT group rats (n = 8); those in the CON group (control, n = 8) were anesthetized without tooth extraction. At age 7 weeks, the rats were subjected to a passive-avoidance task consisting of acquisition and retention trials. Simultaneously, hippocampal glutamate release was measured. First, during the acquisition trial, the rats were placed in a light compartment, and the duration before they entered a dark compartment was measured (reaction latency). Immediately after the rat entered the dark compartment, an electric shock was applied through a grid floor. After 24 h, the retention trial was performed, and the reaction latency was measured in the same manner. Further, a biosensor was used to measure the release of hippocampal glutamate before and after the start of each trial.Results: Regarding the reaction latency during the passive-avoidance task, no significant differences were seen between the groups in the acquisition trial. Reaction latency increased in both groups in the retention trial, but was significantly shorter in the EXT group. Furthermore, hippocampal glutamate release in the acquisition trial was significantly shorter in the EXT group, but in the retention trial, no significant difference in glutamate release was seen between the groups.Conclusion: Molar tooth loss may impede learning and memory.   

143

Influence of presence or absence of teeth adjacent to implants installed immediately into extraction sockets on peri-implant hard tissue levels: an experimental study in the dog.  

AIM: To evaluate the influence of the presence or absence of adjacent teeth on the level of the mesial and distal alveolar bony crest following healing at sites where implants were installed immediately into extraction sockets. MATERIAL AND METHODS: Six Labrador dogs were used. In the right side of the mandible, full-thickness flaps were elevated, and the second, third, and fourth premolars and first molars were extracted. In the left side of the mandible, endodontic treatments of the mesial roots of the third and fourth premolars as well as of the first molars were performed. Full-thickness flaps were elevated, the teeth were hemi-sected, and the distal roots were removed. The second premolars were extracted as well. Subsequently, implants were bilaterally installed with the implant shoulder flush with the buccal bony crest. Implants were placed in the center of the alveoli, but at the fourth premolars, they were placed toward the lingual bony plate of the alveoli. After 3 months of healing, the animals were euthanized and histological sections of the sites prepared. RESULTS: Larger bony crest resorption was observed at the test compared with the control sites, both at the bucco-lingual and mesio-distal aspects. The differences between test and controls for the coronal level of osseointegration were smaller than those for resorption. When data from all mesial and distal sites facing an adjacent tooth were collapsed and compared with those opposing an edentulous zone, lower bony crest resorption and deeper residual marginal defects were found at the sites with neighboring teeth. CONCLUSION: The extraction of teeth adjacent to a socket into which implants were installed immediately after tooth extraction caused more alveolar bone resorption both for the bucco-lingual and at the mesio-distal aspects compared with sites adjacent to a maintained tooth. PMID:22909080

144

Orthodontic movement of a dilacerated maxillary incisor in mixed dentition treatment  

Abstract - Dilaceration is a dental deformity characterized by an angulation between crown and root causing non-eruption of the tooth. It generally occurs following trauma to the deciduous dentition the apices of which lie close to the permanent tooth buds. Surgical extraction used to be the first choice in treating the severely dilacerated teeth. In this case report, it is described how a dilacerated central incisor was successfully moved into alignment in a young patient with proper surgical and orthodontic management avoiding use of prosthetic/implant devices. The panoramic radiograph after the traumatic injury is compared with the one at the end of treatment. The results were sustainable over long-term in both periodontal and aesthetic terms.

145

EPR Dosimetry of Pacific Walrus (Odobenus Rosmarus Divergens) Teeth  

The potential for EPR dosimetry using walrus tooth cementum was examined. Using standard peak to peak methods, individual measurement errors of the dosimetric signal (g = 2.0018) were approximately 350 mGy (1 SD). Linearity of the dose response extended up to 6 kGy for large intact specimens. The dentin was found to have a larger g = 2.005 signal than the cementum and so was not investigated for linearity or sensitivity due to its expected higher organic content. A complex native signal was seen in all samples. A heat induced signal similar to that occurring in human tooth enamel was also observed. The signal was detectable at temperatures as low as 70 deg. C. Deorganification with diethylenetriamine using the Soxhlet extraction procedure decreased the initial dosimetric signal by a factor of 10. (author)

146

Immediate single-tooth implants in the anterior maxilla: 3-year results of a case series on hard and soft tissue response and aesthetics  

Abstract Purpose: The objective of this prospective study was to assess the overall outcome of immediate single implant treatment in the anterior maxilla after a 3-year observation period. Material and methods: Thirty consecutively treated patients with a thick gingival biotype, ideal gingival level/contour and intact socket walls at the time of tooth extraction were treated for single-tooth replacement in the aesthetic zone by two experienced clinicians. Treatment included minimal mucoperiosteal flap elevation, immediate implant placement (NobelReplace TiUnite), insertion of a grafting material between the implant and the socket wall and connection of a screw-retained provisional restoration. The latter was replaced by a cemented crown 6 months thereafter. Patients were clinically and rad...

147

Rationale for esthetic tissue preservation of a fresh extraction socket by an implant treatment concept simulating a tooth replantation  

Abstract - In cases of an immediate insertion and loading of implants after a traumatic loss of the patient's own dentition or due to an inevitable extraction of an anterior tooth, it is essential to provide the patient with an adequate provisional crown. A soft-tissue recession must be avoided, whether it is due to a compression of the peri-implant soft-tissue caused by an over-dimensioned restoration in the cervical collar of the provisional crown or to a too small dimensioned sulcus former. A simulation of the exact dimension of the lost tooth - especially on the cervical part of the new provisional restoration - is expected to preserve all relevant information and allows the design of a naturally looking emergence profile. Based on theoretical considerations and a case report, the auth...

148

Mutual wear evaluation of resin composites when opposing enamel and dentin.  

Mutual wear rates of resin composites and both superficial and deep layers of enamel and dentin were investigated by means of an in vitro wear test. Occlusal surfaces of extracted molars were ground flat to respective layers of enamel and dentin. Hemispherical-shaped styli (n = 8) made of microfilled and microhybrid composites were placed perpendicular to the finished tooth surface (600 grit) in the presence of tap water, and a two-body wear test (75 N load and 1.2 Hz) was performed for 100,000 cycles. The wear depths on both tooth and composite specimens were determined, and the data were statistically analyzed by two-way ANOVA and Boneferroni test (p composite used while those of enamel showed the consistency. PMID:16924615

149

Three-dimensional finite element modeling from CT images of tooth and its validation  

The aim of this study was to develop a three-dimensional (3D) finite element (FE) model of a sound extracted human second premolar from micro-CT data using commercially available software tools. A detailed 3D FE model of the tooth could be constructed and was experimentally validated by comparing strains calculated in the FE model with strain gauge measurement of the tooth under loading. The regression coefficient and its standard error in the regression analysis between strains calculated by the FE model and measured with strain gauge measurement were 0.82 and 0.06, respectively, and the correlation coefficient was found to be highly significant. These results suggested that an FE model reconstructed from micro-CT data could be used as a valid model to estimate the actual strains with acceptable accuracy.   

150

Comparison of clonidine and midazolam as anxiolytic premedication before wisdom tooth surgery: a randomized, double-blind, crossover pilot study  

Purpose Anxiolytic and possible side effects of clonidine 150 ?g compared to midazolam 7.5 mg for premedication in surgical wisdom tooth extraction were evaluated. Methods In a prospective, randomized, double-blind crossover trial, ten patients undergoing bilateral wisdom tooth surgery received clonidine or midazolam orally 1 h before the treatment. Patients receiving midazolam for the first surgery received clonidine at the second surgery and vice versa. The anxiolytic efficacy was evaluated with a visual analogue scale (VAS) upon admission and 30, 50 and 60 min after administration of the medication. Patient satisfaction was recorded on a VAS after surgery and 7 days postoperatively. Results As soon as 30 min after administration of midazolam (p???p???Conclusion Oral administratio...

151

Tooth injury increases expression of the cold sensitive TRP channel TRPA1 in trigeminal neurons  

Objective: Transient receptor potential (TRP) channels, a family of structurally related proteins have been implicated in the sensation of pain and hyperalgesia caused by exogenous and endogenous agonists, as well as touch, pH, and temperature. The objective of this study was to determine the effects of tooth injury on the expression of the cold sensitive channel TRPA1, in the trigeminal ganglion, the primary source of sensory and nociceptive innervation of teeth. Design: We analyzed TRPA1 expression in a rodent model of tooth injury, by Western blot analyses of proteins extracted from trigeminal ganglia. Results: We found that TRPA1 was selectively increased in trigeminal ganglia innervating injured teeth when compared to TRPA1 expression in trigeminal ganglia innervating healthy teeth. C...

152

Compressive shear bond strength of core buildup materials.  

New tooth-colored restorative materials have been developed with the goal of replacing amalgam. These restoratives are marketed as packable composite and ormocer. The purpose of the present study was to compare the compressive shear bond strengths of these new materials with that of hybrid composite and amalgam as core materials. Standardized core buildups were made on four groups of extracted molars, with 10 teeth per group. Three tooth-colored restorative materials (Filtek Z 250, Filtek P 60, and Definite) and an amalgam (SDI Permite) were used. Specimens were placed in a special jig at a 45-degree angle. The compressive shear bond strength was obtained using a universal testing machine. The Kruskal-Wallis test was used to compare the groups, and pairwise comparisons were made by Mann-Whitney U test (P ormocer (Definite) had the lowest. The strengths of packable composite, hybrid composite, and amalgam as core materials were not significantly different (P > .05). PMID:16642907

153

Effect of silver and fluoride ions on enamel demineralization: a quantitative study using micro-computed tomography  

Abstract Background:- This study aimed to investigate the effect of silver and fluoride ions on demineralization of enamel. Methods:- The coronal parts of 40 extracted sound premolars were prepared into tooth blocks. An unvarnished occlusal surface window (OW) and a flat buccal/lingual surface window (FW) were created for each tooth by covering all other surfaces with an acid-resistant varnish. These blocks were randomly allocated into four groups of 10 blocks each and immersed in respective solutions for 5-minutes: Group 1 - 2.36-M silver fluoride; Group 2 - 2.36-M potassium fluoride; Group 3 - 2.36-M silver nitrate; and Group 4 - deionized water. After 7-day immersion in a buffered demineralization solution at pH 4.4, micro-CT scans were taken. Results:- Mean lesion depth in the FW area ...

154

Cost-effectiveness of Endodontic Molar Retreatment Compared with Fixed Partial Dentures and Single-tooth Implant Alternatives  

IntroductionOne of the most challenging situations in dentistry is a failed root canal treatment case. Should a failed root canal-treated tooth be retreated nonsurgically or surgically, or should the tooth be extracted and replaced with an implant-supported restoration or fixed partial denture? These four treatment alternatives were compared from the perspective of cost-effectiveness on the basis of the current best available evidence. MethodsThe costs of the four major treatment modalities were calculated using the national fee averages from the 2009 American Dental Association survey of dental fees. The outcome data of all treatment modalities were retrieved from meta-analyses after electronic and manual searches were undertaken in the database from MEDLINE, Cochrane, ISI Web of Knowledg...

155

Modified technique to extract malpositioned or migrated self-expanding stents from the esophagus and stomach  

Abstract Background and Aim: Various methods have been used to remove self expandable stents (SES) because of either malposition or migration. The main difficulties encountered in such situations are the anatomic obstacle of the lower and upper esophageal sphincters as well as risk of mucosal injury during removal. Methods: We describe a modified approach using an esophagogastroduodenoscope (EGD) in combination with a foreign body hood protector, rat tooth forceps and snare allowing for successful SES removal from the upper gastrointestinal tract in four cases. Results: In all cases, the SES were successfully removed from upper gastrointestinal tract using this technique. No complications were noted after extraction. Conclusion: The foreign body hood protector combined with rat tooth force...

156

Scanning electron microscopic study of dentinal pulpal walls in relation to age and tooth area  

A study was conducted to observe the surface morphological changes of human dentinal pulpal walls in specific areas of the tooth at various ages. Thirty-two extracted human non-carious teeth with single root canals were used. The teeth were divided longitudinally in the bucco-lingual plane and prepared for scanning electron microscopy (SEM). The specimens were divided into two groups (younger and older) according to age. Four central sites of the dentinal pulpal wall, including coronal, cervical, mid-root and apical sections, were selected as specific locations. Under the conditions of this study, six basic types of SEM appearance at dentinal pulpal wall surfaces were identified on the basis of calcospherite shape and mineralization. The appearance of the calcospherites varied according to tooth age and location along the dentinal pulpal walls. (J. Oral Sci. 50, 199-203, 2008)   

157

Three-dimensional analysis of the tooth movement and arch dimension changes in Class I malocclusions treated with first premolar extractions: A guideline for virtual treatment planning  

IntroductionOur objective was to analyze patterns of tooth movement and changes of arch dimension by superimposing 3-dimensional (3D) virtual models. MethodsThe sample consisted of 24 Korean adults with Class I malocclusion and minimal crowding, treated by first premolar extractions, sliding mechanics (0.022-in MBT brackets [3M Unitek, Monrovia, Calif] with 0.019 x 0.025-in stainless steel wire) and moderate anchorage. The 3D virtual maxillary casts at pretreatment and posttreatment were superimposed with the best-fit method. Linear and angular variables were measured with 3Txer program (Orapix, Seoul, Korea). Wilcoxon signed rank and Mann-Whitney tests were used for statistical analysis. ResultsThere was no significant difference in the individual tooth movement between the right and left...

158

Efficacy of Berberine, an Antimicrobial Plant Alkaloid, as an Endodontic Irrigant against a Mixed-culture Biofilm in an In Vitro Tooth Model  

IntroductionBerberine, a plant alkaloid isolated from many medicinal plants, has shown antimicrobial activity against selected oral pathogens. The purpose of this investigation was to evaluate the antimicrobial efficacy of berberine solution against selected endodontic pathogens using a multispecies biofilm tooth model. MethodsThe bacterial species used in the multispecies biofilm tooth model were Fusobacterium nucleatum, Enterococcus faecalis, and Prevotella intermedia. Extracted human anterior teeth were collected and standardized to a length of 14.0 mm. Teeth were cultured in Schaedler broth with the 3 test bacteria strains for 21 days and then randomly assigned to 6 treatment groups (ie, sterile saline, 5.25% NaOCl, 2% chlorhexidine [CHX], 1% CHX, 2 mg/mL berberine, and 1 mg/mL berberi...

159

EPR dosimetry teeth in past and future accidents: A prospective look at a retrospective method  

Accurate assessments of doses received by individuals exposed to radiation from nuclear accidents and incidents such as those at Hiroshima and Nagasaki, the Nevada test site, Cheliabinsk and Mayak are required for epidemiological studies seeking to establish relationships between radiation dose and health effects. One method of retrospective dosimetry which allows for measurement of cumulative gamma ray doses received by exposed individuals is electron paramagnetic resonance spectroscopy (EPR) of tooth enamel. Tooth enamel stores and retains, indefinitely, information on absorbed radiation dose. And teeth are available in every population as a result of dental extraction for medical reasons including periodontal disease and impacted wisdom teeth. In the case of children, deciduous teeth, which are shed between the ages of 7 and 13, can be a very important dosimetric source if documented collection is implemented shortly following an accident.

160

A Case of Dentigerous Cyst in the Maxillary Sinus with Epistaxis  

We report a case of dentigerous cyst in the maxillary sinus with epistaxis. A 55-year-old man complained of recurrent epistaxis on the right side. He also had untreated hypertension. Orthopantomography and computed tomography showed an inverted tooth and dentigerous cyst in the right maxillary sinus. We considered that the cyst was the cause of the epistaxis. Removal of the cyst and extraction of the tooth via the vestibulum oris were performed under general anesthesia. The cyst wall was egg shell-like and bled easily. There were no further episodes of epistaxis after surgery. To the best of our knowledge, no case of dentigerous cyst in the maxillary sinus with epistaxis has previously been reported.   

 
 
 
 
161

Spontaneous eruption of a canine after marsupialization of an infected dentigerous cyst  

A dentigerous cyst is the most common developmental odontogenic cyst. It is a benign and asymptomatic intraosseous lesion that affects the bones of the maxillofacial complex, interfering with tooth eruption. This article reports the spontaneous eruption of a canine after marsupialization of an infected dentigerous cyst and extraction of the deciduous teeth. A radiograph showed a large cyst with a radiolucent area involving the mandibular left deciduous canine and first molar, and the permanent canine and first premolar. Although enucleation is the treatment of choice, marsupialization is the best option for large cysts involving an unerupted permanent tooth, as in this case. The patient was followed for 1 year, and eruption of the permanent canine and first premolar and gradual reduction o...

162

Characteristics of the number of odontoblasts in human dental pulp post-mortem  

Estimation of the time since death is important in forensic medicine, and so far not much is known in employing dental pulp for such purposes. The tooth organ is the hardest organ in the human body, with a loose connective tissue of dental pulp situated within a rigid encasement of mineralized surrounding tissues. Human material was obtained from 31 corpses of people who died in car and train accidents and had healthy oral statuses. Samples were divided into two groups at different environmental temperatures. During the autopsy, the jaws were resected to keep teeth in situ, and every day one tooth was extracted. After decalcification, serial thin sections stained with hematoxylin and eosin were cut. Odontoblasts in the dental pulp were counted and data analysed. Statistical analysis showed...

163

Argon and Nd:YAG Lasers for Caries Prevention in Enamel  

Abstract Objective: The aim of this study was to investigate the effect of Nd:YAG and argon laser irradiations on enamel demineralization after two different models to induce artificial caries. Background data: It is believed that the use of the high-intensity laser on the dental structure can lead to a more acid-resistant surface. Materials and methods: Twenty-one extracted human third molars were sectioned into tooth quarters. The quarters were distributed in three groups: Group I (control), untreated; Group II, Nd:YAG laser (60?mJ, 15?pps, 47.77?J/cm2, 30?sec); and Group III, argon laser (250?mW, 12?J/cm2, 48?sec). Tooth quarters from each group were subjected to two different demineralization models: cycle 1, a 14 day demineralization (pH 4.5; 6?h) and remineralization (pH 7.0; 18?h) s...

164

The effect of strip, tray and office peroxide bleaching systems on enamel surfaces in vitro  

Improvement of the appearance of teeth by whitening systems is one of the goals of modern esthetic dentistry. Vital tooth bleaching is administered in a variety of forms including trays, strips and paint-on gels. The concentrations and conditions of bleaching systems vary considerably between these treatment forms. Objectives This study compared surface changes associated with exposure of human premolar teeth to topical cycling treatments with three different bleaching systems: Opalescence X-Tra Boost (OPXB), Opalescence 20% PF (OP20PF) and Crest Whitestrips Supreme (CWSS), respectively. Methods Extracted human premolars were prepared in Durabase blocks and measured for tooth color, surface microhardness and roughness. Teeth were cycled in a regimen including a pre-test period, test bleach...

165

Mesiodistal tooth size in non-syndromic unilateral cleft lip and palate patients: a meta-analysis.  

OBJECTIVES: To evaluate, using meta-analysis methodology, mesiodistal tooth dimensions in non-syndromic unilateral cleft lip and palate (CLP) patients. MATERIALS AND METHODS: A literature search was conducted using PubMed, Medline, Google Scholar Beta, EMBASE Excerpta Medica, CINAHL, Web of Science, and the Cochrane Collaboration, identifying English and non-English articles reporting on mesiodistal tooth dimensions on the cleft and non-cleft side of non-syndromic unilateral CLP patients. Additional studies were identified by searching reference lists of articles consulted. Only studies with a suitable control group were included. Two examiners independently performed the literature search and data extraction. Using meta-analysis software, data extracted from each selected study were statistically combined using the fixed-effects model. Weighted mean differences, 95 % confidence intervals, and heterogeneity were calculated for each measurement. RESULTS: Four articles fulfilling the inclusion criteria were located and included in the meta-analysis. Maxillary incisors and first molars were found to be significantly larger on the non-cleft side while mandibular incisors and premolars were larger on the cleft side, in non-syndromic unilateral CLP patients. On the cleft side, maxillary premolars and second molars were larger in cleft than control patients while incisors were smaller, whereas all mandibular teeth were larger in cleft patients. On the non-cleft side, all maxillary teeth except for the central incisors were larger in the cleft than control patients, while all mandibular teeth were larger in the cleft patients except for lateral incisors. CONCLUSIONS: Non-syndromic unilateral CLP patients tend to have larger posterior but smaller anterior teeth compared with the general population. Comparing sides, unilateral CLP patients tend to have smaller maxillary but larger mandibular teeth on the cleft than on the non-cleft side. CLINICAL RELEVANCE: Given that obtaining a stable, functional, and esthetic occlusion requires a thorough evaluation of tooth size, knowledge about trends in tooth size variations in CLP patients can help with dental and orthodontic treatment planning. PMID:23011523

166

Effect of low-level laser therapy on the healing process after tooth replantation: a histomorphometrical and immunohistochemical analysis.  

Success of tooth replantation is limited because part of the replanted tooth is lost because of progressive root resorption. This study used histomorphometry and immunohistochemistry to evaluate the effect of low-level laser therapy (LLLT) on the healing process of rat teeth replanted after different extra-oral periods, simulating immediate and delayed replantation. Sixty Wistar rats (Rattus norvegicus albinus) had their maxillary right incisors extracted and randomly assigned to six groups (n = 10): C4, C30 and C45, in which the teeth were replanted 4 min (immediate), 30 min (delayed) and 45 min (delayed) after extraction, respectively, and L4, L30 and L45, in which the teeth were replanted after the same extra-alveolar times, but the root surfaces and the alveolar wounds were irradiated with a gallium-aluminum-arsenate (GaAlAs) diode laser before replantation. The animals were sacrificed after 60 days. The anatomic pieces containing the replanted teeth were obtained and processed for either histomorphometrical analysis under optical microscopy or immunohistochemical expression of receptor activator of nuclear factor Kappa-B (RANK), and its ligand (RANKL), osteoprotegerin (OPG) and tartrate-resistant acid phosphatase (TRAP) proteins. Areas of external replacement and inflammatory root resorption were observed in all groups, without statistically significant differences (P > 0.05). Ankylosis was more frequent in L30 than in C30 (P < 0.05). RANKL immunostaining predominated over RANK and OPG immunostaining in both groups with immediate tooth replantation (P < 0.05). For the 45-min extra-alveolar time, however, there was greater evidence of RANK immunostaining compared to RANKL for both control and laser-treated groups (P < 0.05). Positive TRAP immunostaining predominated in L4 and L30 (P < 0.05). In conclusion, under the tested conditions, the treatment of the root surface and the alveolar wound with LLLT did not improve the healing process after immediate and delayed tooth replantation in rats. PMID:21244626

167

76 FR 15992 - Endangered and Threatened Species Permit Applications  

...recovery purposes to collect flower buds for chromosome counts from Arizona...spider (Neoleptoneta microps), Tooth Cave spider (Neoleptoneta myopica), Tooth Cave pseudoscorpion (Tartarocreagris...beetle (Texamaurops reddelli), Tooth Cave ground beetle...

168

Decay (Cavities/Caries)  

... Tooth decay is the destruction of your tooth enamel, the hard, outer layer of your teeth. It ... bacteria in plaque produce acids that attack tooth enamel. The stickiness of the plaque keeps these acids ...

169

Analysis of the socket bone wall dimensions in the upper maxilla in relation to immediate implant placement  

Abstract Background: Animal and human researches have shown that immediate implant placement into extraction sockets failed to prevent socket dimensional changes following tooth extraction. It has been suggested that a minimal width of 1-2 mm of buccal bone is necessary to maintain a stable vertical dimension of the alveolar crest. Aim: To determine the dimensions of the bony wall at extraction sites in the esthetic zone (anterior teeth and premolars in the maxilla) and relate it to immediate implant placement. Methods: As part of an ongoing prospective randomized-controlled multicenter clinical study on immediate implant placement, the width of the buccal and palatal bony walls was recorded at 93 extraction sites. Results: The mean width of the buccal and palatal bony walls was 1 and 1.2 ...

170

Immediate Versus Nonimmediate Placement of Implants for Full-Arch Fixed Restorations: A Preliminary Study  

PurposeTo compare the success rates, after 1 year of loading, for implants placed immediately after tooth extraction and in healed sites in patients undergoing extraction of all residual teeth for rehabilitation with a fixed, full-arch, implant-supported prosthesis. Materials and MethodsA retrospective case series study was conducted of 38 patients treated from June 2004 to June 2008 by extraction of all remaining teeth and implant placement in both mature bone and at the extraction site in the same procedure. After osteointegration, the implants were restored with fixed full-arch prostheses. The marginal bone loss around the implants was measured after 1 year. The success rate according to Buser criteria was calculated for the immediate and nonimmediate implants. ResultsA total of 41 arch...

171

Comparing the effects of chlorhexidine and persica on alveolar bone healing following tooth extraction in rats, a randomised controlled trial  

Chlorhexidine is broadly prescribed by clinicians for treating extraction socket wounds; however, studies have reported adverse effects for chlorhexidine. Persica, a herbal antibacterial agent, could be an alternative for chlorhexidine. The aim of this randomised controlled trial was to investigate the effects of persica and chlorhexidine on alveolar bone healing following tooth extraction in rats. Eighteen Wistar rats were randomly allocated to three study groups: 0.2% chlorhexidine, 10% persica and controls (tap water). The rats were mouth-rinsed for 14?days. On day?8, the mandibular right first molars of all the rats were extracted. On day?21, the rats were euthanized and histological slides of their extraction sockets were prepared. The amount of new bone formation and the number of in...

172

Prospective Evaluation of Immediate and Delayed Provisional Single Tooth Restorations  

Purpose The purpose of this study was 2-fold: to determine whether there is a significant difference in the hard and soft tissue response comparing immediate with delayed implant placement after tooth removal, with immediate provisionalization, in maxillary anterior sites; and to determine and compare the crestal bone levels as the primary endpoint variable for implants placed and immediately temporized in extraction sites, to implants placed into extraction sites after the extraction site has been grafted and healed for 4 months, all immediately restored with an anatomic provisional restoration. This aim was to be evaluated by measuring crestal bone levels on standardized digital radiographs of the implants, using implant threads as a monitor of magnification and a pre-extraction referenc...

173

Human histologic analysis of mineralized bone allograft (Puros) placement before implant surgery.  

Because clinicians are placing more dental implants, it is becoming more important to maintain bone volume after tooth extraction. This article discusses the various bone-augmentation materials available to the clinician and illustrates a case report of particulate mineralized bone allograft (Puros) placement after extraction. Exposure of the grafted site after 5 months revealed a hard bony structure. Human histologic analysis at the light microscopic level revealed nonvital spicules of mature calcified bone having a highly organized matrix surrounded by viable noncalcified immature bone matrix, or osteoid. It was concluded that mineralized human allograft demonstrated the formation or remodeling of bone histologically and was clinically useful to maintain bone volume for implant placement after extraction. To the authors' knowledge, this is the first publication to demonstrate human histology of particulate mineralized bone allograft (Puros) after placement into an extraction site. PMID:15119456

174

Effects of an atelocollagen sponge during the wound healing of tooth extraction sockets at an early stage  

The purpose of this study was to evaluate the morphological and molecular effects of atelocollagen sponges placed in rat tooth extraction sockets in their early stages of wound healing. Right incisors of rats were extracted, and atelocollagen sponges were placed into the tooth extraction sockets. Sockets without atelocollagen served as controls. Extraction socket tissues were histologically evaluated for 3 weeks after surgery, and mRNA expression levels for type I collagen and osteocalcin were also quantified. At the time that non-specific fibrous connective tissue invaded the alveolar bone ridge area of the sockets from the outside in the control group, new bone formation was seen up to the level of the alveolar bone ridge in the experimental group. There was a significantly higher expression level for type I collagen mRNA in the experimental group, whereas there was no significant difference in the expression of osteocalcin mRNA between the two groups. These results suggest that atelocollagen plays a role in maintaining space by stimulating collagen production but does not accelerate cell proliferation or osteoinduction.   

175

Oropharyngeal tuberculosis: An unusual presentation  

Aims and objectives: To compare the success rate of implant placed immediately in extraction socket vs implant placed delayed in extraction socket. Materials and Methods: The study comprised of 8 patients (6 male and 2 female, aged from 14 to 58 year) for evaluation of implant placement immediately (i.e. Group – A) or delayed (i.e. Group – B) into extraction site, in which at 12 sites implants were placed. Results: The inclusion criteria for implantation was tooth/teeth with one or two degree mobility, root stumps, tooth with failure root canal treatment and extraction sockets. HI-TEC TRX-OP (Life Care) with abutment, non-submerged, tapered at apical 5 mm, sand-blasted & acid etched surfaced implants were used. These are one stage single implants made of commercially pure titanium. The length of implants used was 10 mm and 13 mm and diameter was 3.70 mm and 4.50 mm. The vertical bone dimension was determined by palpation and radiograph (intra-oral periapical, orthopantomograph and dentascan in some patients). Gingival condition, bone condition was examined clinically and radiographically. Discussion: Post-operative evaluation was done under clinical parameters (i.e. Pain (VAS), Swelling, Stability (By Glickman method), Gingival status, Probing depth (By Williams Periodontal probe), Patient's compliance / satisfaction, Complications (If any) and Radiological parameters was (Intra-oral periapical radiograph, orthopantomograph, Dentascan). Conclusion: Overall conclusion drawn from this study was that both the groups are showing similar results but Group-A is slightly better than Group-B PMID:19157915

176

Flapless alveolar ridge preservation utilizing the ''socket-plug'' technique: clinical technique and review of the literature.  

Abstract It has been documented that after every extraction of one or more teeth, the alveolar bone of the respective region undergoes resorption and atrophy. Therefore, ridge preservation techniques are often employed after tooth extraction to limit this phenomenon. The benefits of a flapless procedure include maintenance of the buccal keratinized gingiva, and prevention of alterations to the gingival contours and migration of the mucogingival junction that are often experienced after raising a flap. The purpose of this article is to review the literature concerning flapless ridge preservation techniques with the aid of collagen plugs for occlusion of the socket. The term ''socket plug technique'' is introduced to describe these techniques. The basic steps of the ''socket-plug technique'' consist of atraumatic tooth extraction, placement of the appropriate biomaterials in the extraction site, preservation of soft tissue architecture employing a flapless technique and placement and stabilization of the collagen plug. A case example is presented that illustrates the steps used in this technique. PMID:23145803

177

Use of viscera extract from hybrid catfish (Clarias macrocephalus×Clarias gariepinus) for the production of protein hydrolysate from toothed ponyfish (Gazza minuta) muscle.  

Proteolytic activity of viscera extract from hybrid catfish (Clarias macrocephalus×Clarias gariepinus) was studied. The optimal pH and temperature were 9.0 and 50°C, respectively, when toothed ponyfish (Gazza minuta) muscle was used as a substrate. When viscera extract from hybrid catfish was used for the production of protein hydrolysate from toothed ponyfish muscle, extract concentration, reaction time, and fish muscle/buffer ratio affected the hydrolysis and nitrogen recovery (NR) (pmuscle hydrolysis were 3.5% hybrid catfish viscera extract, 15min reaction time and fish muscle/buffer ratio of 1:3 (w/v). High correlation between the degree of hydrolysis (DH) and NR (R(2)=0.974) was observed. Freeze-dried hydrolysate had a high protein content (89.02%, dry weight basis) and it was brownish yellow in colour (L(?)=63.67, a(?)=6.33, b(?)=22.41). The protein hydrolysate contained a high amount of essential amino acids (48.22%) and had arginine and lysine as the dominant amino acids. PMID:23122156

178

77 FR 7175 - Endangered and Threatened Species Permit Applications  

...infernalis) Helotes mold beetle (Batrisodes venyivi) Kretschmarr Cave mold beetle (Texamaurops reddelli...baronia) Tooth Cave ground beetle (Rhadine persephone) Tooth...absence surveys of Sonora tiger salamander (Ambystoma...

179

Phantom Tooth Pain (Atypical Odontalgia)  

Phantom Tooth Pain (Atypical Odontalgia) PDF Version: ( English / Spanish / Japanese ) Atypical odontalgia, also known as atypical facial pain or phantom tooth pain, is characterized by chronic pain in ...

180

Má oclusão de Classe I de Angle, com ausência congênita e impacção de dentes permanentes/ Angle Class I malocclusion with congenitally absence and impaction of permanent teeth  

Abstract in portuguese Este artigo relata o tratamento ortodôntico de um paciente com 14 anos e 6 meses de idade, portador de má oclusão de Classe I de Angle, que apresentava ectopia e impacção do dente 45 e ausência congênita do dente 35. O caso foi tratado com extração do dente 45 e fechamento dos espaços inferiores. Documentações inicial, final e pós-tratamento serão apresentadas e discutidas. Esse caso foi apresentado à Diretoria do Board Brasileiro de Ortodontia e Ortopedia (more) Facial (BBO), representando a categoria 7, livre escolha, como parte dos requisitos para a obtenção do título de Diplomado pelo BBO. Abstract in english This article reports the orthodontic treatment of a 14 year and 6 months old patient that had a Angle Class I malocclusion with an ectopic position and impaction of the tooth 45 and congenitally absence of tooth 35. This case was treated with the extraction of the tooth 45 and space closure in the lower arch. Initial, final and post-treatment orthodontic records will be presented and discussed. This case was presented to the Brazilian Board of Orthodontics and Facial Orth (more) opedics (BBO), representing the category 7, free choice, as part of the requirements for achieving the title of BBO diplomate.

 
 
 
 
181

Classification of maxillary canine transpositions in Japanese children: A report of 10 cases  

The aim of the present study was to examine the prevalence rate and treatment outcome of maxillary canine transposition in Japanese children according to the conventional standard and our new additional consideration of the classification. From 140 cases with ectopic canines diagnosed in the Pediatric Dental Clinic of Niigata University Medical and Dental Hospital, we selected 10 transposition cases as the present subjects. Out of 10 cases, 4 were males and 6 females. Six were classified into type A: the mesio-distal positional interchange of the canine and the first premolar, 2 cases into type B: the mesio-distal transposition of the canine and the lateral incisor, and the other 2 cases into type C: the present new classification that showed the vertical transposition of the canine and the first premolar within the developmental bone. The prevalence rate of types A and B resembled the previous papers regarding the ratio of sex and bilateral occurrence. Although 3 cases in type A, one case in type B and one case in type C could finally be aligned in the normal tooth order, every one of the types A and B cases were aligned in the reverse order. For every one case in types A and C, the transposed canines were extracted. It is recommended that pediatric dentists take an orthopantomogram during early mixed dentition as a routine practice in order to detect anomalies of tooth eruption, such as tooth transposition, as early as possible.   

182

THE Nd-YAG LASER IS USEFUL IN PREVENTION OF DENTAL CARIES DURING ORTHODONTIC TREATMENT  

Plaque control during the course of orthodontic treatment is not an easy task, and dental caries are not an unlikely complication. We examined the possibility of controlling dental caries with Nd-YAG laser irradiation in orthodontic patients. As a preliminary experiment, we used the Nd-YAG laser to irradiate an extracted tooth and then left it to soak in lactic acid. The decay of the tooth was evaluated with a scanning electron microscope (SEM); tooth decay was inhibited by the action of the laser. Twenty patients undergoing orthodontic treatment for early decalcification of the teeth (white spot lesions) were selected, and photographs were taken of their oral cavities. White spot lesions on the four incisors and two canines of the maxilla were traced on tracing paper, and their areas were calculated by computer. Ten of the patients received laser treatment and acidulated phosphate fluoride solution (APF); the other ten acted as the control group. Between 11 and 12 months later, we photographed the oral cavity as we had previously; the white spot lesions were again traced and their areas calculated. The changes in the areas of the white spots of the laser-irradiated and control groups showed the following increases: laserirradiated group, 1.41 times; controls, 2.87 times. The difference was statistically significant. These results demonstrate that Nd-YAG laser irradiation with application of APF acts as an effective method of caries control during orthodontic treatment.   

183

Biological restorations as a treatment option for primary molars with extensive coronal destruction: report of two cases  

Abstract in portuguese Este artigo descreve dois casos clínicos de reconstrução de molares decíduos com extensa destruição coronária por meio de restaurações biológicas, em crianças de 4 e 5 anos. Após avaliação clínica e radiográfica, os fragmentos dentais heterógenos foram submetidos à colagem ao remanescente dental preparado usando sistema adesivo (Caso 1) ou cimento resinoso de presa dual (Caso 2) sobre uma camada de hidróxido de cálcio e uma base de ionômero de vidro. (more) Foi realizado ajuste oclusal e aplicação tópica de flúor sobre a superfície dentária. Controles clínico e radiográfico foram realizados periodicamente e os dentes restaurados foram acompanhados por 4 e 3 anos respectivamente, até a exfoliação. Por meio destes dois relatos, os autores discutem os aspectos técnicos, além das vantagens e desvantagens das restaurações biológicas como tratamento alternativo para restauração de molares decíduos. Abstract in english This article reports the cases of two young children aged 4 and 5 years, in whom biological restorations using tooth fragments were placed in primary molars with severely damaged crowns due to extensive carious lesions. After radiographic and clinical evaluation, tooth fragments obtained from extracted teeth in stock were autoclaved, adjusted to the prepared cavity and bonded to the remaining tooth structure with either adhesive system (Case 1) or dual-cure resin-based ce (more) ment (Case 2) over a calcium hydroxide layer and a glass ionomer cement base. Occlusal adjustment was performed and topical sodium fluoride was applied to tooth surface. Periodical clinical and radiographic controls were carried out and the restored teeth were followed up for 4 and 3 years, respectively, until exfoliation. In these two reports, the technical aspects are described and the benefits and disadvantages of biological restorations as an alternative treatment for rehabilitation of severely destroyed primary molars are discussed.

184

Fluorine uptake into human enamel around fluoride-containing dental materials during cariogenic pH cycling  

Using PIGE (Proton Induced Gamma Emission) technique at TARRI (Takasaki Advanced Radiation Research Institute), Japan, we measured fluorine (F) uptake into the tooth enamel around two fluoride-containing materials during caries progression using pH cycling. Class V cavities in extracted human teeth were drilled and filled with fluoride-containing materials (i.e. 'Fuji IX' (FN) and 'UniFil flow with MEGA bond' (UF)) and a non-fluoride-containing material (i.e. 'SOLARE with MEGA bond' (SO)). Three 120 {mu}m longitudinal sections including the filling material were obtained from each tooth. In order to simulate daily acid attack occurring in the oral cavity, the pH cycling (pH 6.8-4.5) was carried out for 1, 3 and 5 weeks, separately. After pH cycling, the caries progression in all specimens was observed using transverse microradiography (TMR). The F and calcium distributions of the specimens were evaluated using PIGE and PIXE techniques. The F distribution of the specimens clearly showed the F uptake from FN into enamel adjacent to the filling material, while the F uptakes from UF and SO were not detected. For UF, the MEGA bond (non-fluoride-containing) between the tooth and UniFil flow interfered with the F absorption into the tooth. For FN, the amount of F uptake into the subsurface enamel increased during pH cycling. The amount of F uptake in 5-week pH cycling had significantly higher value compared to those in 1- and 3-week pH cycling. For UF and SO, there were no significant differences between the different durations of pH cycling. Among fluoride-containing materials, there were some differences in the F uptake with increased pH cycling, which could possibly lead to obtaining difference in clinical performance. The data obtained using PIGE and PIXE techniques were useful in understanding the benefit of fluorine by means of fluoride-containing material for preventing caries.

185

Comparison of the Structures of Tooth Germs Transplanted into the Subcutaneous Tissue or the Kidney Capsule of Mice  

Transplantation experiments are a common method in tooth developmental research. Many organs have been previously selected as hosts ; however, there is little information comparing developmental differences in the transplanted tooth among these host organs. In the present study, the authors examined the effect of transplantation into the subcutaneous tissue and the kidney capsule for 4 weeks using E13.5 mandibular first molar tooth germs from mice. The shape and size of the tooth crown of the tooth transplanted into the subcutaneous tissue are smaller than those of the tooth transplanted into the kidney capsule and a normal tooth in vivo. However, the number and arrangement of cusps of the transplanted tooth were similar to those of a normal tooth. Compared with those of the tooth transplanted into the kidney capsule, development and calcification of the transplanted tooth progressed slowly in the subcutaneous tissue. These differences may cause movement of the transplanted tooth ; the subcutaneous tissue is composed of loose connective tissue and the transplanted tooth moves easily in the subcutaneous tissue, although the tooth transplanted into the kidney capsule is maintained tightly between the kidney capsule and kidney cortex. However, cell differentiation and cell function were not affected by movement of the tooth germ ; enamel and dentin were formed in the transplanted tooth in both the subcutaneous tissue and the kidney capsule. These findings suggest that development of the transplanted tooth may be affected by the host organ.   

186

Modern concepts in understanding and management of the "dry socket" syndrome: comprehensive review of the literature  

Postoperative swelling following different surgical strategies is an area of great interest. The main part of literature on the topic deals with swelling after extraction of low impacted third molar. In this review, we have analyzed publications of the last 20 years with a pubmed search using the following key words: impacted third molar, swelling third molar, wisdom tooth, edema jaw, corticosteroids and extraction third molar, antibiotic prophylaxis and tooth extraction. Attention has often been focused on corticosteroid therapy administered by diverse routes (orally, IV, IM, topically) and at different time schedules (before or after surgery or both). This investigation revealed how the use of different molecules and dosages makes the obtained results hardly comparable. Similar conclusions can be drawn from studies aimed at evaluating the efficacy of antibiotic therapy administered either before or after surgery. A complete review has also to take into account different surgical strategies used including various flaps, no traumatic osteothomy, and primary or secondary closure. The use of pharmacological therapy and application of an ice pack is critical in the postoperative period and has always provided positive results. However, even if it is difficult to come to definite conclusions, due to the variability of the design of studies analyzed, the postoperative discomfort identified with edema, pain and trismus following wisdom tooth removal is influenced by various factors such as the difficulty of the surgical procedure involved, age and gender of the patient, and experience of the surgeon. The pharmacological therapy when performed with corticosteroids seems to improve control of the postoperative swelling related with this kind of surgeries. PMID:20537783

187

Coronal displacement of cementum in impacted teeth: As age marker  

Dental cementum is a vital tissue that demonstrates continuous apposition throughout the life of a tooth. This study was conducted on 130 impacted mandibular third molars extracted from healthy patients, aged between 18 and 38 years. The buccolingual ground sections were prepared and the distance between the edges of enamel and cementum were measured with micrometer attached to a light microscope. A significant correlation (r=0.56) between age and coronal displacement of cementum in impacted teeth was calculated and a regression equation was derived for age determination.

188

Time evolution of the reaction front in a subdiffusive system  

Using the quasistatic approximation, we show that in a subdiffusion--reaction system the reaction front $x_{f}$ evolves in time according to the formula $x_{f} \\sim t^{\\alpha/2}$, with $\\alpha$ being the subdiffusion parameter. The result is derived for the system where the subdiffusion coefficients of reactants differ from each other. It includes the case of one static reactant. As an application of our results, we compare the time evolution of reaction front extracted from experimental data with the theoretical formula and we find that the transport process of organic acid particles in the tooth enamel is subdiffusive.

189

How long do multirooted teeth with furcation involvement survive with treatment?  

Data sourcesA Medline search and handsearching of the following journals were carried out: International Journal of Periodontics and Restorative Dentistry, Journal of Clinical Periodontology, Journal of Periodontal Research and Journal of Periodontology as well as reference lists of publications selected.Study selectionTo be eligible for inclusion in this review, studies had to be longitudinal in nature. Prospective and retrospective cohort studies were considered. Studies were screened and quality assessed independently by two reviewers. Review articles, case reports and studies of fewer than 5-years' duration were excluded, as were those not providing information on tooth survival or furcation involvement.Data extraction and synthesisData was abstracted independently by two reviewers. Ow...

190

A review of root resective therapy as a treatment option for maxillary molars.  

Restorative treatment planning is often confounded when periodontal attachment loss, caries or tooth fracture involves the furcation area of the tri-rooted maxillary molars. Although such involvement invariably diminishes the long-term prognosis of the affected teeth, extraction is not always an option. Root resective therapy, which removes the involved root plus its associated crown portion (trisection), is one of several treatment modalities that can be used in such cases. This article reviews the indications and contraindications for root resective therapy, describes the techniques of surgical trisection and presents a case in which combined resective, endodontic and prosthetic management resulted in a successful outcome. PMID:9103795

191

Raman spectroscopy with an integrated arrayed-waveguide grating.  

An integrated arrayed-waveguide grating fabricated in silicon-oxynitride technology is applied to Raman spectroscopy. After its validation by reproducing the well-known spectrum of cyclohexane, polarized Raman spectra are measured of extracted human teeth containing localized initial carious lesions. Excellent agreement is obtained between the spectra of healthy and carious tooth enamel measured with our integrated device and spectra recorded using a conventional Raman spectrometer. Our results represent a step toward the realization of compact, hand-held, integrated spectrometers, e.g. for the detection of dental caries at an early stage. PMID:22139265

192

Effect of different grit sizes of diamond rotary instruments for tooth preparation on the retention and adaptation of complete coverage restorations  

Statement of problem Internal adaptation and retention are important factors for the longevity of crown restorations. However, how tooth surface roughness associated with diamond rotary cutting instruments affects the retention and internal adaptation of complete coverage restorations remains unknown. Purpose This study evaluated the relationship between the surface roughness of prepared teeth and the internal adaptation and retention of complete coverage restorations after preparation with diamond rotary cutting instruments of different grit sizes. Material and methods Ninety-two extracted human teeth were divided into 4 groups and assigned to different final grit sizes of the diamond rotary instruments used for preparation following a grit decreasing sequence from coarse (125 to 150 mm),...

193

Local anesthetics: dentistry’s most important drugs, clinical update 2006  

Following tooth extraction, the alveolar ridge undergoes an inevitable remodeling process that influences implant therapy of the edentulous area. Socket grafting is a commonly adopted therapy for the preservation of alveolar bone structures in combination or not with immediate implant placement although the biological bases lying behind this treatment modality are not fully understood and often misinterpreted. This review is intended to clarify the literature support to socket grafting in order to provide practitioners with valid tools to make a conscious decision of when and why to recommend this therapy. PMID:17260521

194

Dislodged lower right third molar tooth into the parapharyngeal space.  

Lower third molar teeth can be dislodged into fascial tissue spaces when they are extracted or elevated out of their sockets. Thankfully, this rarely occurs. We present a case report on a lower right wisdom tooth dislodged into the right parapharyngeal space on its removal from the socket and the subsequent management of this rare complication. CLINICAL RELEVANCE: Though a rare complication, clinicians have to be aware that lower third molars can be dislodged into tissue spaces and the importance of prompt appropriate management. PMID:22238995

195

Removal of a root from the maxillary sinus using functional endoscopic sinus surgery  

Displacement of a root into the maxillary sinus is an infrequent consequence of extraction of upper molar teeth. Conventional treatment is centred around surgical access through the tooth socket or via the Caldwell-Luc technique. This case illustrates the use of a minimally invasive method for retrieval of a dislodged root fragment with Functional Endoscopic Sinus Surgery (FESS). This technique is normally reserved for treatment of chronic sinusitis and is shown in this case report to be successful and less traumatic for the patient. It also emphasises the necessity to treat each case on its own merit and base treatment options around the clinical scenario

196

Implant Placement and Immediate Loading with Fixed Restorations in Augmented Sockets. Five-year Results. A Case Report.  

Abstract In this report, a case is presented in which a patient received eight implants ten months after tooth extraction and socket preservation. The implants were placed in both arches (maxilla = 4, mandible = 4) and immediately loaded using fixed restorations; they remained functional over five years. We observed no changes in bleeding on probing or plaque index, but a 1.5-mm probing attachment level loss was observed during the first three years (mean: 0.25 mm/year) with no subsequent changes. PMID:22204326

197

Avaliação nutricional e da proteína e do óleo de semente de baru (Dipteryx alata Vog.)  

Summary This paper reports the management of two clinical cases, in which the upper right central incisor was fused with a supernumerary tooth and the upper left central incisor was macrodontic. A radiographic examination revealed that the fused teeth had two separate roots. Hemisectioning of the fused teeth was performed, the supernumerary portion was extracted and the remaining part was reshaped to remove any sharp margins and to achieve a normal morphology. The macrodontic central incisors were not treated. At 12-months post-surgery there were no periodontal problems and no hypersensitivity. Orthodontic treatment was performed to appropriately align the maxillary teeth and to correct the malocclusion. PMID:22351919

198

Corticotomy and Tissue Engineering for Orthodontists: A Critical History and Commentary  

Twenty-first century discoveries in cellular and molecular biology have explained how clinicians in medicine and dentistry can engineer tissue regeneration in a way that makes room for orthodontists. This presumes that they define themselves as dentoalveolar orthopedists and restrict corticotomy procedures to “selective alveolar decortication,” with or without grafting. With a new vision (orthodontic tooth movement, through a healing wound), orthodontists can modulate physiological internal strains—similar to those of distraction osteogenesis in long bones—to define novel and more stable alveolus phenotypes, reducing the need for bicuspid extractions and minimizing orthognathic surgery morbidity. The aim of this treatise, using critical rationalism and analytica...

199

A conservative approach in the management of inflammatory dentigerous cyst in transitional dentition: a case report.  

Dentigerous cysts are benign odontogenic cysts that develop from the reduced enamel epithelium related to the crown of an unerupted and/or impacted tooth. Inflammatory dentigerous cyst is a variety of dentigerous cyst that is mostly found in the mixed dentition, and the treatment modalities range from enucleation to marsupialization. By extracting the infected primary teeth, opening the cyst, and ensuring continuous drainage, spontaneous eruption of the involved permanent teeth occurs into the dental arch even if they are severely dislocated. The purpose of this report is to describe the successful treatment of a large dentigerous cyst by conservative surgical management. PMID:22919949

200

Postextraction bleeding following a fever: a case report.  

Postoperative hemorrhage is one of the few serious complications that can occur as a result of dental procedures. We report a case of an elderly patient with postextraction bleeding caused by dengue hemorrhagic fever (DHF). Although a major sequel of DHF is bleeding secondary to thrombocytopenia, prolonged hemorrhage as a result of extraction of tooth has not been reported. In the current scenario of emerging and reemerging infections worldwide, dengue is gaining global prominence. This case documents the course and progression of this disease from a dental perspective and highlights the as yet unreported capacity of causing oral complications after dental treatment. PMID:22999964

 
 
 
 
201

The effect of Piper betle and Psidium guajava extracts on the cell-surface hydrophobicity of selected early settlers of dental plaque  

The adhesion of early settlers of dental plaque to the tooth surface has a role in the initiation of the development of dental plaque. The hydrophobic surface properties of the bacteria cell wall are indirectly responsible for the adhesion of the bacteria cell to the acquired pellicle on the tooth surfaces. In this study, the effect of aqueous extract of two plants (Psidium guajava and Piper betle) on the cell-surface hydro-phobicity of early settlers of dental plaque was determined in vitro. Hexadecane, a hydrocarbon was used to represent the hydrophobic surface of the teeth in the oral cavity. It was found that treatment of the early plaque settlers with 1 mg/ml extract of Psidium guajava reduced the cell-surface hydrophobicity of Strep. sanguinis, Strep. mitis and Actinomyces sp. by 54.1%, 49.9% and 40.6%, respectively. Treatment of these bacteria with the same concentration of Piper betle however, showed a comparatively lesser effect (< 10%). It was also observed that the anti-adhesive effect of the two extracts on the binding of the early plaque settlers to hexadecane is concentration dependent. (J. Oral Sci. 48, 71-75, 2006)   

202

Connective tissue grafts in conjunction with implants installed immediately into extraction sockets. An experimental study in dogs.  

AIM: To evaluate the influence of a sub-epithelial connective tissue graft placed at the buccal aspect of implants installed immediately after tooth extraction on the dimensional changes of hard and soft tissues. MATERIALS AND METHODS: In six Labrador dogs a bilateral partial- thickness dissection was made buccal to the second mandibular premolar. At the lingual aspect, full-thickness flaps were elevated. The teeth were extracted and implants installed immediately into the distal socket. A connective tissue graft was obtained from the palate and applied to the buccal aspect of the test sites, whereas contra-laterally, no graft was applied. The flaps were sutured to allow a non-submerged installation. After 4 months of healing, the animals were sacrificed, ground sections were obtained and histomorphometric analyses were performed. RESULTS: After 4 months of healing, all implants were integrated (n = 6). Both at the test and at the control sites bone resorption occurred: 1.6 mm and 2.1 mm, respectively. The difference was not statistically significant. The coronal aspect of the peri-implant soft tissue was wider and located more coronally at the test compared with the control sites. The differences were statistically significant. CONCLUSIONS: The application of a connective tissue graft placed at the buccal aspect of the bony wall at implants installed immediately after tooth extraction yielded a minimal preservation of the hard tissues. The peri-implant mucosa, however, was significantly thicker and more coronally positioned at the test compared with the control sites. PMID:22463707

203

Cranial skeletal biology  

Background: The preservation or reduction of alveolar ridge resorption following tooth extraction is important in patients especially for those intended for implants at a later stage. One way to achieve this is by using membranes, graft materials, and biodegradable space fillers to prevent alveolar bone resorption and promote regeneration. A major attraction for using biodegradable and biocompatible polymers as space fillers for ridge preservation is their safety profile in comparison to xenograft materials like lyophilized bone and collagen. Materials and Methods: Biocompatible polylactide space fillers were fabricated by fusing porous polylactide particles. The sponges were loaded with drugs by placing them in the respective solutions. Pseudomonas aeruginosa was isolated from a chronic periodontitis patient and in vitro anti-microbial evaluation was done with the drug loaded sponges. Results: Chlorhexidine loaded space filler showed significant anti microbial effect against multiple drug resistant Pseudomonas aeruginosa isolated from a patient with chronic periodontitis. Conclusion: The results of this study indicate that biodegradable drug releasing polylactide space fillers has the potential to be used for ridge preservation following tooth extraction. Release of drugs in the socket may prove useful in preventing development of alveolar osteitis post extraction which can interfere with normal healing of the socket. Synthetic biodegradable polymers also exhibit a controlled degradation rate to achieve complete resorption within the intended time. PMID:12748650

204

Confocal laser scanning microscopy for the study of the morphological changes of the postextraction sites.  

A better understanding of the remodeling process of postextraction sockets is essential in dental treatment planning. The aim of this study was to evaluate whether confocal laser scanning microscopy (CLSM) can be applied to imaging contour changes of postextraction sites, as well as to its quantification with image analysis of obtained three-dimensional images. This work describes a new application of the CLSM technique. The system used was the OLS3100-USS, LEXT model (Olympus®). CLSM was used for the surface analysis of the extraction site. The measurements taken with CLSM were: (1) mesio-distal distance, (2) alveolar ridge thickness, and (3) vestibular and lingual alveolar ridge height. Results of study cast scanning at baseline, 1 and 3 months after tooth extraction, with CLSM are well-detailed images of postextraction areas. The CLSM technique used in study casts is a valid method to measure the dimensional changes that happen in the edentulous area after tooth extraction. This technique allows the evaluation of changes in mesio-distal distance, thickness of the alveolar ridge and alveolar ridge height based on the measurements on the alveolar contours. PMID:22553827

205

Serial extraction: 20 years of follow-up.  

This paper reports a case treated by a serial extraction program at the mixed dentition stage followed by a corrective orthodontic treatment, with a long-term follow-up period. Twenty years after the interceptive treatment, a harmonious face was observed along with treatment stability in the anterior posterior direction, deep overbite (which has been mentioned as a disadvantage of the serial extraction program), and a small relapse of anterior tooth crowding. All these conditions have been regarded as normal occurrences for most orthodontic treatments with a long-term follow-up period. This case report demonstrated that the establishment of a serial extraction protocol determined relevant esthetic changes that afforded an improvement of the patient's self-esteem, with a positive social impact. Furthermore, the low cost of this protocol permits the use of this therapy with underprivileged populations. It is important to emphasize that an early correction of tooth crowding by this protocol does not guarantee stability, but small relapses do not invalidate its accomplishment. PMID:23032213

206

Histometric study of socket healing after tooth extraction in rats treated with diclofenac/ Estudo histométrico do reparo alveolar após extração dental em ratos tratados com diclofenaco  

Abstract in portuguese O objetivo do presente trabalho foi investigar se a administração de diclofenaco interfere no processo de reparo alveolar em ratos. Foram utilizados 42 ratos Wistar, dos quais 21 receberam 10mg/kg/dia de diclofenaco e o restante solução salina. Os animais foram submetidos a extração dos incisivos superiores direito, e sacrificados 7, 14 e 21 dias após a avulsão dental. A formação progressiva de osso e a redução do volume de coágulo sangüíneo e tecido conjun (more) tivo no período de 1 a 3 semanas após a extração dental foram quantificadas através do método histométrico de contagem de pontos. O tratamento com o diclofenaco causou significante atraso na neo-formação óssea, associado a um atraso na organização e remissão do coágulo sangüíneo. Abstract in english The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood (more) clot and connective tissue from 1 to 3 weeks after tooth extraction was quantified using the histometric point-counting method. Diclofenac treatment caused a significant delay in new bone formation in association with an impairment of blood clot remission/organization.

207

Osseointegrated implants  

Despite being considered noncritical size defects, extraction sockets often require the use of bone grafts or bone graft substitutes in order to facilitate a stable implant site with an aesthetically pleasing mucosal architecture and prosthetic reconstruction. In the present study, the effect of novel TiO2 scaffolds on dimensional ridge preservation was evaluated following their placement into surgically modified extraction sockets in the premolar region of minipig mandibles. After six weeks of healing, the scaffolds were wellintegrated in the alveolar bone, and the convex shape of the alveolar crest was preserved. The scaffolds were found to partially preserve the dimensions of the native buccal and lingual bone walls adjacent to the defect site. A tendency towards more pronounced vertical ridge resorption, particularly in the buccal bone wall of the nongrafted alveoli, indicates that the TiO2 scaffold may be used for suppressing the loss of bone that normally follows tooth extraction. PMID:2094653

208

True anatomical zirconia implants for molar replacement: a case report from an ongoing clinical study with a 2-year follow-up  

Abstract This article describes a case report of an ongoing clinical investigation with modified root-analogue zirconia dental implants. We present a 40-year-old female patient with root caries and chronic apical periodontitis after an unsuccessful root canal treatment. The tooth was carefully extracted, and the socket was cleaned by means of curettage. The root was modified by application of macro-retentions and micro-retentions, and laser scanned, and an exact replica was milled from a zirconia block. Five days after extraction, a one-piece zirconia implant was placed into the extraction socket by gentle tapping with a hammer and a mallet. The soft tissue healed unremarkably around the implant within 3 days. The definitive restoration with a composite crown was performed 3 months after e...

209

Clinical outcome of submerged vs. non-submerged implants placed in fresh extraction sockets  

Abstract Aim: The aim of this study was to compare the clinical outcome of submerged vs. non-submerged tapered implants placed into fresh extraction sockets. Materials and methods: A prospective, controlled, multicenter, randomized, clinical trial has been performed in two centers in Rome and Torino (Italy). Thirty healthy patients were recruited according to the following inclusion criteria: need for an immediate post extraction implant, ages between 18 and 70, horizontal defect depth <2 mm, smokers <10 cigarettes/day and absence of any circumstance or condition that could represent contraindications to implant surgery. The patients were randomly allocated to submerged or non-submerged treatment groups immediately after flap elevation and tooth extraction. Submerged implants were exposed ...

210

Surface treatment at the cervical region and its effect on bone maintenance after immediate implantation: an experimental study in dogs  

Objective The aim of this study was to evaluate the effect of surface treatment at the cervical region of endosseous dental implants on the alveolar bone remodeling after implantation immediately after tooth extraction in a dog model. Study design The third and fourth premolars of 6 dogs were bilaterally extracted with a full-thickness flap, and threaded implants presenting a textured or a polished surface at the cervical regions were placed on the distal root extraction sockets. Submerged healing was allowed for 4 weeks, and bone-to-implant contact (BIC) and buccal and lingual bone loss were morphometrically measured. Results The BIC and lingual bone loss were not significantly different between textured and polished groups. Significantly lower buccal bone loss (P < .01) was observ...

211

Is autologous platelet concentrate beneficial for post-extraction socket healing? A systematic review  

The aim of this systematic review was to assess if the use of autologous platelet concentrates may be beneficial to the healing of extraction sockets. Medline, Embase and Cochrane Central Register of Controlled Trials were searched using a combination of specific search terms. Hand searching of the relevant journals and of the bibliographies of reviews was also performed. Prospective comparative studies evaluating the effect of a platelet concentrate on fresh extraction sockets were included. Outcome variables related to hard and soft tissue healing, aesthetics and postoperative discomfort were considered. A methodological study quality assessment was made. The initial search yielded 425 articles, eight were finally included. 207 tooth extractions (104 tests and 103 controls) in 115 patien...

212

Periodontal regeneration versus extraction and prosthetic replacement of teeth severely compromised by attachment loss to the apex: 5-year results of an ongoing randomized clinical trial  

Abstract Aims: Aim of this randomized, long-term clinical trial was to compare clinical- and patient-based outcomes following periodontal regeneration or extraction and replacement of hopeless teeth with chronic perio-endo lesions and/or attachment loss to or beyond the apex. Methods: Fifty patients presenting with generalized severe periodontitis and at least one hopeless tooth to be extracted for periodontal reasons were entered in this study. The test treatment consisted in the application of a regenerative strategy to 25 hopeless teeth. The control treatment consisted in the extraction of the 25 hopeless teeth and their replacement with conventional or implant-supported fixed partial dentures. Results: In the control group, 14 teeth were replaced with implant-supported restorations, ei...

213

Reasons for Permanent Tooth Extractions in Japan  

BACKGROUND: There has been no nationwide study in Japan on reasons for extraction of permanent teeth. This survey was aimed to determine the reasons for extraction of permanent teeth in Japan.METHODS: Five thousand, one hudred and thirty-one dentists were selected by systematic selection from the 2004 membership directory of the Japan Dental Association. The dentists selected were asked to record the reason for each extraction of permanent teeth during a period of one week from February 1 through 7, 2005. Reasons for tooth extraction were assigned to five groups: caries, fracture of teeth weakened by caries or endodontics, periodontal diseases, orthodontics, and other reasons.RESULTS: A total of 2,001 dentists (response rate of 39.1%) returned the questionnaires, and information on 9,115 extracted teeth from 7,499 patients was obtained. The results showed that caries and its sequela (totally 43.3%, 32.7% and 10.6%, respectively) and periodontal disease (41.8%) were the main reasons for teeth extraction. Extraction due to caries or fracture was commonly observed in all age groups over 15 years of age, whereas periodontal disease was predominant in the groups over 45 years of age.CONCLUSIONS: Most of the permanent teeth were extracted due to caries and its sequela and periodontal disease. Prevention and care for dental caries for all age groups and periodontal disease for over middle age groups are required.J Epidemiol 2006; 16: 214-219.   

214

Porcine-Derived Xenograft Combined with a Soft Cortical Membrane versus Extraction Alone for Implant Site Development: A Clinical Study in Humans.  

Background: An adequate alveolar crest is essential for implant placement in terms of esthetics and function. The objective of this randomized clinical trial was to compare the preservation of the alveolar ridge dimensions following tooth extraction using porcine-derived xenograft combined with a membrane versus extraction-alone (EXT) sites. Methods: Fifteen patients who required double extraction of contralateral premolars and delayed implant placement were randomly selected to receive both ridge-preservation procedure and EXT. The test sites (alveolar ridge preservation [ARP]) included 15 sockets treated using a corticocancellous porcine bone xenograft (OsteoBiol® Gen-Os; Tecnoss srl, Giaveno, Italy) associated with a soft cortical membrane (OsteoBiol® Lamina; Tecnoss srl), while the corresponding control sites (EXT) were left without grafting for EXT. Horizontal and vertical ridge dimensions were recorded at baseline and 6 months after extractions. Results: After 6 months, the EXT sites showed a significantly greater reabsorption of the buccolingual/palatal dimension of the alveolar ridge (3.7?±?1.2?mm) compared with the ARP sites (1.8?±?1.3?mm). The mean vertical ridge height reduction in the control sockets was 3.1?±?1.3?mm at the buccal sites and 2.4?±?1.6?mm at the lingual sites compared with 0.6?±?1.4 and 0.5?±?1.3?mm, respectively, in the test sockets. The differences between test and control sockets were not significant for the mesial and distal measurements. Conclusions: The placement of a porcine xenograft with a membrane in an extraction socket can be used to reduce the hard tissue reabsorption after tooth extraction compared with EXT. PMID:22082037

215

Evaluation of the cavity margins after Er:YAG laser ablation of the enamel and dentin  

This study investigates the checks of cavity margin after enamel and dentin ablation. The Er:YAG laser enamel and dentin ablation can be directly connected with the danger of cracks originating in the enamel near the cavity. This study evaluates the quality of the enamel edges after Er:YAG laser preparation. The enamel and dentin of buccal surfaces were ablated by the Er:YAG laser radiation. An Erbium:YAG laser system with the energy of 200 mJ was used to generate 200 microsecond(s) long pulses of mid-infrared 2.94 micrometers light in multimode configuration. The laser was operating in a free running mode, the repetition rate being 0.5 Hz with average laser power of 100 mW. Laser radiation was focused on the tooth tissue. Water cooling was used during the procedure in order to prevent tooth tissue destruction. The time of laser preparation was 5 minutes. A cavity of class V was prepared. The teeth were immersed into 0.5% basic fuchsin and then centrifuged at 6000 rev/min for 20 minutes. The microphotographs of the margins stained with 0.5% basic fuchsin were made and then the longitudinal section of the teeth were evaluated. The micrographs of the longitudinal section were checked and measured afterwards. The effect of the investigated laser irradiation on the origin of cracks was analyzed in the scanning electron microscope. Micrographs of each tooth before and after the laser ablation were compared. Micrographs of the intact teeth after extraction present the cracks of the enamel. They depend on the pressure exerted during extraction. The influence of the laser ablation proper is it bears no signs of new cracks. The conclusions of this study demonstrate the non-invasive nature of the Er:YAG laser ablation of the hard dental tissues.

216

The effect of 2 different diameter cast posts on tooth root fracture resistance in vitro.  

Prosthetic treatment frequently involves the restoration of endodontically treated teeth (ETT), which in turn implies that there has been a reduction of the crown due to previous restorative treatment, trauma and/or endodontic manipulations. The prognosis of a restored ETT is very much dependent on pre-endodontic status of the tooth, the quality of the endodontic treatment, the amount remaining tooth structure and the bone support. The aim of this study is to measure fracture resistance of extracted premolar teeth restored with 2 different diameter posts. Extracted premolars were collected and stored in physiologic solution at 5 degrees C. The teeth were examined for fractures by direct and transillumination observation and 40 premolars were accepted for the study. The PC were modelled using the appropriate diameter plastic pattern for the post and Pattern Resin (GC) was used to model the core part of the PC. The PC patterns were invested and cast in cobalt chromium alloy and then cemented using zinc phosphate cement. Fracture resistances of the samples were tested in an "Instron 4301" (Instron Series IX Automated Material Testing System Version 5) with a loading speed of 0.5 mm/min. The data for each sample was recorded graphically. Both groups were analyzed using the t-test (p<0.01) in relationship to the mean value of that group. Post and cores significantly reduce the fracture resistance of the tooth and should be used only to secure retention and resistance form for full coverage crowns. Teeth with a larger diameter post have a reduced fracture resistance than teeth with a smaller diameter. PMID:16687913

217

The International Caries Detection and Assessment System (ICDAS): an integrated system for measuring dental caries.  

This paper describes early findings of evaluations of the International Caries Detection and Assessment System (ICDAS) conducted by the Detroit Center for Research on Oral Health Disparities (DCR-OHD). The lack of consistency among the contemporary criteria systems limits the comparability of outcomes measured in epidemiological and clinical studies. The ICDAS criteria were developed by an international team of caries researchers to integrate several new criteria systems into one standard system for caries detection and assessment. Using ICDAS in the DCR-OHD cohort study, dental examiners first determined whether a clean and dry tooth surface is sound, sealed, restored, crowned, or missing. Afterwards, the examiners classified the carious status of each tooth surface using a seven-point ordinal scale ranging from sound to extensive cavitation. Histological examination of extracted teeth found increased likelihood of carious demineralization in dentin as the ICDAS codes increased in severity. The criteria were also found to have discriminatory validity in analyses of social, behavioral and dietary factors associated with dental caries. The reliability of six examiners to classify tooth surfaces by their ICDAS carious status ranged between good to excellent (kappa coefficients ranged between 0.59 and 0.82). While further work is still needed to define caries activity, validate the criteria and their reliability in assessing dental caries on smooth surfaces, and develop a classification system for assessing preventive and restorative treatment needs, this early evaluation of the ICDAS platform has found that the system is practical; has content validity, correlational validity with histological examination of pits and fissures in extracted teeth; and discriminatory validity. PMID:17518963

218

Enfermedad periodontal en oncológicos: Factor indicativo de exodoncias?  

Abstract in spanish En este estudio se verificó las indicaciones de exodoncias en pacientes con cáncer en región de cabeza e cuello, que serán sometidos a radioterapia, en el servicio de Oncología de la Facultad de Odontología da Universidad Federal de Minas Gerais. Fueran evaluadas 114 historias clínicas y radiografías panorámicas y periapicales y fueran divididos de acuerdo con las indicaciones de exodoncias. Estas indicaciones fueron por caries, enfermedad periodontal, asociacion (more) es de caries y periodontitis, falta de soporte para prótesis, diente incluidos, dientes extruidos, y en algunos casos dientes con indicaciones de extracciones exclusivamente por causa de la radioterapia. Los resultados mostraron que la mayor parte de indicaciones de exodoncias fueron debido a caries (21,05%) y enfermedades periodontales (26,31%). Debido a la predisposición a la pérdida de inserción periodontal y al riesgo de su progresión, pacientes que serán sometidos a la radioterapia de cabeza y cuello deberán ser evaluados en relación a la condición periodontal y a las indicaciones de exodoncia. Este estudio mostró que el diagnóstico de la enfermedad periodontal fue el principal factor relacionado con la indicación de exodoncias previamente al tratamiento oncológico Abstract in english The aim of this study was to describe the indication of the exodontias in patients with head embedded tooth, extruded tooth and some cases when indication is because of radiotherapy. The results show that caries (21, 05%) and periodontitis (26, 31%) were the biggest indications of exodontias in these patients. Due to a tendency of attachment loss and bone destruction and the risk of progression, patients that will be under head and neck radiotherapy should be evaluated on (more) the periodontal status e tooth extraction indications. This study shows that the diagnosis of periodontal disease was the main indication to teeth extractions previous to oncological treatment

219

Comparing the effects of chlorhexidine and persica on alveolar bone healing following tooth extraction in rats, a randomised controlled trial.  

Chlorhexidine is broadly prescribed by clinicians for treating extraction socket wounds; however, studies have reported adverse effects for chlorhexidine. Persica, a herbal antibacterial agent, could be an alternative for chlorhexidine. The aim of this randomised controlled trial was to investigate the effects of persica and chlorhexidine on alveolar bone healing following tooth extraction in rats. Eighteen Wistar rats were randomly allocated to three study groups: 0.2% chlorhexidine, 10% persica and controls (tap water). The rats were mouth-rinsed for 14 days. On day 8, the mandibular right first molars of all the rats were extracted. On day 21, the rats were euthanized and histological slides of their extraction sockets were prepared. The amount of new bone formation and the number of inflammatory cells in the extraction socket for each rat were recorded. Data were analysed using linear regression and Mann-Whitney tests. There was no significant difference between the control group and the intervention groups in terms of new bone formation and inflammatory cell count. The mean new bone formation was significantly higher in the persica group than in the chlorhexidine group. There was a significant association between new bone formation and inflammatory cell count in the entire sample. In conclusion, there were no significant differences between rinsing with tap water and rinsing with 0.2% chlorhexidine and 10% persica in enhancing extraction socket wound healing in rats. Extraction socket wound healing in rats was better enhanced with 10% persica than 0.2% chlorhexidine. PMID:20938794

220

Management of furcation-involved teeth. A retrospective analysis.  

In the present study, data from more than 550 periodontally diseased patients with more than 1100 furcation invasions were retrospectively analysed. There were apparent differences in the distribution of different furcation degrees in patient populations treated by 2 differently experienced operators. However, treatment modality patterns were rather similar. Scaling during periodontal flap surgery was the most often performed treatment procedure in degree I (97-98%) and II (75-83%) involvements. About 44% of degree III involved teeth were extracted. In order to determine the influence of degree of furcation involvement, tooth type and operator variability on treatment modality, logistic regression analysis was applied. Degree of furcation involvement was an important indicator variable in all models. Scaling as a sole measure was mainly performed in relation to degree I of furcation involvement. With every increase in degree, the odds of scaling decreased by factor 12.7. The odds of root resection was upper 1st molars 46 x higher than in wisdom teeth or lower 2nd molars with the same degree of involvement, but only 3.3 x higher than in lower 1st molars. Tunnel preparation as well as regenerative procedures were mainly confirmed to lower molars. Operator variability was only introduced as a covariate in the extraction model. hence, despite of different operator skill and severity of periodontal disease in treated populations, decision for one or the other treatment modality seems to depend essentially on degree of furcation involvement as well as tooth type. PMID:8613558

 
 
 
 
221

The success rate of immediate implant placement of mandibular molars: a clinical and radiographic retrospective evaluation between 2 and 8 years.  

BACKGROUND: Dental implants, indicated for re-establishing both mastigatory and aesthetic functions, can be placed in the sockets immediately after tooth extraction. Most studies investigate the anterior and upper regions of the dental arch, whereas few examine longitudinal appraisal of immediate implant installation in the mandibular molar region. OBJECTIVE: The aim of this retrospective study was to evaluate the success rate of immediate dental implants placement in mandibular molars within a follow-up period as long as 8 years. MATERIALS AND METHODS: Seventy-four mandibular molar implants after non-traumatic tooth extraction between 2002 and 2008 were examined in the study. All implants were evaluated radiographically immediately after prosthesis placement, 1 year after implantation, and by the end of the experimental period, in 2010. Clinical evaluation was done according to [Albrektsson et al. (1986) The International Journal of Oral & Maxillofacial Implants, 1, 11-25] success criteria for marginal bone loss. The mean bone losses, calculated as the difference between the final evaluation measures and those taken by the end of the first year of implant, were compared using Kruskal-Wallis test with a significance level of 5%. RESULTS: All implants presented clinical and radiographic stable conditions, that is, 100% success rate. Significant bone loss was not found between final evaluation and that of the first functional year (P > 0.05). CONCLUSION: Immediate implant placement of mandibular molars proved to be a viable surgical treatment given the high success rate up to 8 years after implantation. PMID:22462471

222

Primary intraosseous odontogenic carcinoma arising in an odontogenic cyst or de novo: a clinicopathologic study of six new cases  

Background: There is a controversy about exact time of bone healing. The aim of this study was evaluation of bone formation and change of density after mandibular third molar extraction. Methods: Radiographs were taken from 16 empty tooth sockets immediately after extraction of mandibular third molars and 2, 4 and 6 months later under similar condition. The radiographs were digitized and the density numbers of pixels were calculated. Then, socket and neighbor regions were compared using Photoshop software. Three expert observers evaluated and compared the radiographs by the longitudinal radiographic assessment (LRA) method. Paired t-test and McNemar test were used to analyze the data and investigate the inter-observer reliability, respectively. Results: Analysis of the quantitative digital subtraction radiography (QDSR) data indicated that the difference between the digital numbers of interest points and reference points has been decreased during the months 2, 4 and 6 but the difference between the month 4 and 6 was not significant. The alternative method indicated that the mean digital numbers in the socket within 0and 2 months period was less than 128 and within 4 and 6 months was more than 128. In evaluation of LRA method, lamina dura started to change gradually in month 2 and it might disappear completely after 6 months. Conclusion: Both QDSR and LRA methods can be used in evaluation of the rate of bone formation in the tooth socket but the former is more precise. PMID:16448921

223

Short-term vs long-term calcium hydroxide therapy after immediate tooth replantation: a histomorphometric study in monkey's teeth.  

Endodontic treatment is an important step of tooth replantation protocols, but the ideal moment for definitive obturation of replanted teeth has not yet been established. In this study, a histomorphometric analysis was undertaken to evaluate the repair process on immediate replantation of monkey's teeth after calcium hydroxide (CH) therapy for 1 and 6?months followed by root canal filling with a CH-based sealer (Sealapex(®) ). The maxillary and mandibular lateral incisors of five female Cebus apella monkeys were extracted, kept in sterile saline for 15?min, replanted and splinted with stainless steel orthodontic wire and composite resin for 10?days. In Group I (control), definitive root canal filling was performed before tooth extraction. In Groups II and III, CH therapy started after removal of splint, and definitive root canal filling was performed 1 and 6?months later, respectively. The animals were euthanized 9?months after replantation, and specimens were processed for histomorphometric analysis. In all groups, epithelial attachment occurred at the cementoenamel junction or very close to this region; the areas of resorption on root surface had small extension and depth and were repaired by newly formed cementum; and the periodontal ligament was organized. Statistical analysis of the scores obtained for the histomorphometric parameters did not show any statistically significant difference (P?=?0.1221) among the groups. The results suggests that when endodontic treatment is initiated 10?days after immediate replantation and an antibiotic regimen is associated, definitive root canal filling can be performed after a short-term CH therapy. PMID:22051142

224

Peripheral nerve may regulate the jaw bone resorption after tooth extraction.  

A various amount of alveolar ridge resorption is likely to occur after tooth extraction, making it difficult to restore the missing teeth with either endosseous dental implants or prosthodontics approaches. It is commonly thought that the bone resorption is due to the absence of the mechanical stimulation from the occlusal force. However, regulation of the bone mass is a complex homeostatic system involved in hormonal, paracrine/autocrine, mechanical and neuronal nature. Studies have shown that the central and peripheral nervous system play an important role in bone remodeling. The hypothalamus integrates peripheral and central signals, and sends efferent hormonal and neuronal signals in response to stimulation. Numerous neuropeptides detected in the bone marrow have effect on the osteoblast and osteoclast. After tooth extraction, great loss of the axons is observed in the edentulous bone. So we speculate that innervation in the alveolar bone regulates the bone resorption in edentulous area. Methods to promote the nerve regeneration are expected to prevent the jaw bone resorption. The hypothesis also implies that after the placement of the oral implant the abundant nerves in the alveolar bone can increase the bone healing ability and long term survival rate of the implant. PMID:18514432

225

Usefulness of a radiolucent spacer in radiation therapy for cancer of the tongue  

For the purpose of preventing osteonecrosis following interstitial irradiation for tongue cancer, a Radiolucent Spacer was prepared with the intention of reducing bone dose by keeping the mandible at a distance from the source. Because of its radiolucency, the Spacer made of silicone enables to perform X-P while inserted, and more exact dose calculation. For 6 cases in which 8 mm-spacer was used, dose reduction rate for surface of lower gingiva corresponded to 42.3%, average of tumor dose for TDF. For 51 cases in which the observation of course was practicable for 2 years--9 years and 4 months, averaging 5 years and 7 months, the incidence of osteonecrosis was 0%, and therefore, Spacer of not less than 8 mm-thickness is thought useful as prosthesis. Extraction of the tooth was done at the start of irradiation, but the healing course was always favorable. The most aseptic possible alveolectomy and complete closure of the wound are necessary for tooth extraction. (author).

226

Development of a New Diagnosis Method for Incipient Caries in Human Teeth Based on Thermal Images under Pulse Heating  

A new noninvasive diagnosis method based on the pulse heating thermographic NDT was proposed for incipient caries of human teeth. Experiments were conducted to study the applicability of the proposed method to the quantitative evaluation of location and shape of the incipient caries as well as the quantitative diagnosis of the degree of incipient caries. The incipient caries were artificially introduced to the extracted human teeth with various severities. Impulse heat flux by the xenon flash lamp was applied to the surface of the tooth and sequential thermal images were taken by the high-speed infrared thermography. It was found that the caries were clearly identified as the localized high temperature region in the sequential thermal images. A coefficient of the temperature descent was obtained from sequential thermal images. It was found that the degree of the demineralization, i. e. the degree of incipient caries was evaluated from the temperature descent coefficient. Further the proposed technique was applied to the detection of natural incipient caries in an extracted human molar tooth. It was found that natural incipient caries was also clearly identified in the thermal images.   

227

[Atypical surgical approach to the extraction of retained teeth].  

Indication to extract deep impacted teeth as well as the surgical approaches is controversally discussed in the litterature. Based on a clinical case report we describe two atypical approaches, one is extraoral the other lingual for removing tow deeply impacted teeth. The revue of the litterature shows that atypical surgical approaches are only indicated in particular clinical situations. The indication to remove the teeth and the approach depends on the patient's compliance as well as the experience of the operator. In the reported case the extraoral approach is justified by the chronical dentogene infection with fistulisation and cutaneus changes in the submandibular region. Based on the much easier access to the tooth and the only minimal cutaneus modifications in this case, we recommand the extraoral approach for extraction of deep impacted teeth in some special cases like the one we present. PMID:15587600

228

Oral infection, regular alcohol drinking pattern, and myocardial infarction  

Oral infections have been associated with an increased risk for myocardial infarction (MI) and other cardiovascular diseases (CVD). Conversely, low, regular alcohol consumption is associated with a lower association of CVD. The objective was to test the novel hypothesis that oral infections are modified by regular alcohol drinking which has the effect of lowering the incidence of MI's. The effect has been observed where tooth extractions where carried out due to infections and compared with extractions unconnected to infections. Oral infections and in particular periodontal infections impose an infectious load on the health in many people. In its advanced forms (periodontal pockets 6mm) periodontitis affects 10-15% of adults. The infection runs a chronic course with exacerbations. The bact...

229

Characterization of root surface periodontal ligament following avulsion, severe intrusion or extraction: preliminary observations  

Abstract - This study employed novel topographic and histological techniques to assess remaining periodontal ligament (PDL) in a convenience sample of avulsed and intruded human permanent incisors and extracted premolars. Seventeen human teeth (eight avulsed, five severely intruded and four uninjured extracted) were evaluated for the distribution and physical characteristics of adherent root surface PDL. The topographic distribution of PDL was assessed by staining roots with malachite green and determining the proportion of remaining PDL within selected regions on four aspects of each tooth. In order to characterize mechanical damage to PDL, serial transverse sections of roots were stained with hematoxylin and eosin and examined at magnifications of 40x to 800x. The sections were photograp...

230

Effects of experimental osteoporosis and low calcium intake on postextraction sockets of rats  

Summary This study analysed the initial effects of the combination of oestrogen deficiency with a calcium-deficient diet on alveolar bone repair. Sixty-three 3-month-old female rats were either ovariectomized (OVX, n-=-42) or sham-operated (SHAM, n-=-21). Among the 42 ovariectomized rats, 21 received standard commercial food (OVX) and 21 received food with low calcium content (ESP). The mandibular first molars were extracted bilaterally 15-days after ovariectomy or sham surgery. The rats were weighed and killed at 7, 21 and 45-days after tooth extraction. The results were evaluated by descriptive microscopic analysis, histomorphometry of the trabecular and osteoid volume and mast cell counts. Analysis of the results indicated that trabecular volume and mast cell counts increased significan...

231

A prospective, randomized-controlled clinical trial to evaluate bone preservation using implants with different geometry placed into extraction sockets in the maxilla  

Abstract Aim: The primary objective of this study was to determine the association between the size of the void established by using two different implant configurations and the amount of buccal/palatal bone loss that occurred during 16 weeks of healing following their installation into extraction sockets. Material and methods: The clinical trial was designed as a prospective, randomized-controlled parallel-group multicenter study. Adults in need of one or more implants replacing teeth to be removed in the maxilla within the region 15-25 were recruited. Following tooth extraction, the site was randomly allocated to receive either a cylindrical (group A) or a tapered implant (group B). After implant installation, a series of measurements were made to determine the dimension of the ridge and...

232

Esthetic alveolar ridge preservation with calcium phosphate and collagen membrane: Preliminary report  

Objective The objective of this study was to evaluate clinically, histologically and radiographically a ridge preservation technique used on extraction sockets grafted with biphasic calcium phosphate (BCP) and a resorbable collagen membrane. Material and methods Patients having a labial socket wall defect more than one-third in mesio-distal socket width after maxillary central incisor tooth extraction were included. The labial defect was sealed with resorbable collagen membrane and the defect filled with BCP. The grafted socket was covered with a resorbable collagen wound dressing material. The treated sockets were evaluated after a 4-month healing period when implants were placed and followed for up to 12 months. Results There were 8 subjects enrolled in this study. A statistical differen...

233

Bone regeneration at implants placed into extraction sockets of maxillary incisors in dogs  

Abstract Aim: To compare the influence of autologous or deproteinized bovine bone mineral as grafting material on healing of buccal dehiscence defects at implants installed immediately into the maxillary second incisor extraction socket in dogs. Material and methods: In the maxillary second incisor sockets of 12 Labrador dogs, implants were installed immediately following tooth extraction. A standardized buccal defect was created and autologous bone particles or deproteinized bovine bone mineral were used to fill the defects. A collagen membrane was placed to cover the graft material, and the flaps were sutured to fully submerge the experimental areas. Six animals were sacrificed after 2 months, and six after 4 months of healing. Ground sections were obtained for histological evaluation. R...

234

Immediate implants at fresh extraction sockets: an experimental study in the beagle dog comparing four different implant systems. Soft tissue findings  

de Sanctis M, Vignoletti F, Discepoli N, Munoz F, Sanz M. Immediate implants at fresh extraction sockets: an experimental study in the beagle dog comparing four different implant systems. Soft tissue findings. J Clin Periodontol 2010; 37: 769-776 doi: . Abstract Objectives: To evaluate whether different implants placed immediately upon tooth extraction may affect the dimension and composition of the peri-implant soft tissues. Material and Methods: Eight beagle dogs received implants randomly installed into the distal socket of 3P3 and 4P4. Four commercially available implant systems were evaluated: 3i Osseotite Certain straight; Astra MicroThread-OsseoSpeed; Thommen SPI Element; and Straumann ITI standard. Each animal provided four test implant sites. All animals were sacrificed 6 weeks af...

235

Radiographic alveolar bone changes following ridge preservation with two different biomaterials  

Abstract Objectives: The aim of this randomized controlled trial was to evaluate radiographical bone changes following alveolar ridge preservation with a synthetic bone substitute or a bovine xenograft. Methods: Alveolar ridge preservation was performed in 27 patients randomized in two groups. In the test group (n=14), the extraction socket was treated with Straumann bone ceramic (SBC) and a collagen barrier membrane (Bio-Gide), whereas in the control group (n=13) with deproteinized bovine bone mineral and the same barrier. Standardized periapical X-rays were taken at 4 time points, BL: after tooth extraction, GR: immediately after socket grafting, 4M: 16 weeks, 8M: 32 weeks post-operatively. The levels of the alveolar bone crest at the mesial (Mh), and distal (Dh) and central aspects of t...

236

Initial Study on Facilitating Wound Healing After Tooth Extraction by Using Microbial Fiber Membrane-Flagyl  

PurposeThe aim of the present study was to investigate the efficacy of microbial fiber membrane-Flagyl (MF-FLA) on facilitating hemostasis and wound healing and its anti-inflammatory ability after tooth extraction. Materials and MethodsFor the animal experiment, 60 healthy male rabbits were randomly divided into control and treatment groups. Each group included 5 subgroups corresponding to different experimental periods (1, 2, 4, 8, and 12 weeks) and each subgroup had 6 rabbits. After the different experimental periods, the rabbits were killed, and the mandible was removed for histologic examination and analysis. For the human trial, 80 patients (32 males and 48 females; age range, 13 to 32 years), who were undergoing orthodontic treatment and who had undergone bilateral extraction of teet...

237

Sunitinib related osteonecrosis of jaw: a case report  

A 58-year-old woman presented to the Oral and Maxillofacial Surgery Clinic experiencing severe limited mouth opening and exposed bone in the socket of the right mandibular third molar 8 months following the extraction of the tooth. The patient had been treated during the year before her presentation with sunitinib, an antiangiogenic drug, for renal cell carcinoma. The clinical, radiographic, and histologic picture of a chronic nonhealing extraction socket was consistent with osteonecrosis of the jaw (ONJ), although she had never been treated with bisphosphonates or corticosteroids. The treatment with sunitinib was discontinued and the patient was treated with antibiotics and physiotherapy for 12 weeks with complete recovery. Sunitinib may cause osteonecrosis of the jaw after oral surgical ...

238

Immediate loading after implant placement following tooth extraction up-regulates cellular activity in the dog mandible  

Abstract Objectives: The aim of this study was to investigate cellular activity of the cervical portion of peri-implant tissue due to immediate loading after implant placement following tooth extraction from the dog mandible, in terms of morphological, immunohistochemical and molecular characteristics. Material and methods: A sand-blasted implant was inserted into the root septum bone of each extraction socket and was connected to a superstructure made from resin and then covered with an expanded polytetrafluoroethylene membrane. Implants without the superstructure were used as the non-loading control group. Animals were sacrificed 1-3 weeks later and specimens were observed using light microscopy and mRNA levels were analyzed by real-time polymerase chain reaction. Results: The new bone f...

239

Buccal Plate Augmentation: A New Alternative to Socket Preservation  

Alveolar ridge resorption occurs after tooth extraction and has the potential to either complicate implant placement or impair the final esthetic result. Techniques to preserve natural bone and soft tissue contours are of great interest to clinicians and patients because even subtle postextraction buccal plate resorption may have significant clinical effects, particularly in the esthetic zone. Buccal plate augmentation (BPA) is a novel approach for ridge preservation aiming to avoid recession of the facial wall of the socket without interfering with the natural healing mechanism of the extraction socket. It consists of placement of bone graft material over an intact buccal plate, underneath the soft tissues in a surgically created pouch with an aim to maintain or augment the soft tissue es...

240

Confocal laser scanning microscopy for the study of the morphological changes of the postextraction sites  

Abstract A better understanding of the remodeling process of postextraction sockets is essential in dental treatment planning. The aim of this study was to evaluate whether confocal laser scanning microscopy (CLSM) can be applied to imaging contour changes of postextraction sites, as well as to its quantification with image analysis of obtained three-dimensional images. This work describes a new application of the CLSM technique. The system used was the OLS3100-USS, LEXT model (Olympus). CLSM was used for the surface analysis of the extraction site. The measurements taken with CLSM were: (1) mesio-distal distance, (2) alveolar ridge thickness, and (3) vestibular and lingual alveolar ridge height. Results of study cast scanning at baseline, 1 and 3 months after tooth extraction, with CLSM a...

 
 
 
 
241

Comparative Radiographic Evaluation of Alveolar Bone Healing Associated With Autologous Platelet-Rich Plasma After Impacted Mandibular Third Molar Surgery  

Purpose This study radiographically evaluated the performance of autologous platelet-rich plasma (PRP) applied in tooth sockets. Patients and Methods Thirty extractions of bilateral impacted mandibular third molars were performed in 15 volunteers (7 men, 8 women; 18 to 22 years old). After extraction of right and left mandibular third molars, the socket at 1 side received the autologous PRP (PRP group) and the other was filled with blood clot (control group). Millimeter periapical radiographs were obtained 7 days, 1 month, and 2, 3, and 6 months postoperatively. Radiographic bone density was quantified 3 times by the same examiner at different moments using HLImage 97 software, and data were statistically analyzed by Statgraf 7.0 software (analysis of variance and Tukey test). Results In g...

242

Demineralised human dentine matrix stimulates the expression of VEGF and accelerates the bone repair in tooth sockets of rats  

Objective: In this study we investigated the possible use of human demineralised dentine matrix (DHDM), obtained from the extracted teeth, as bone graft material and evaluated the expression of vascular endothelial growth factor (VEGF) induced by this material in the healing process of tooth sockets of rats. Design: To evaluate bone regeneration and expression of VEGF induced by DHDM, thirty-two male Wistar rats weighing approximately 200g were used. After maxillary second molar extraction, the left sockets were filled with DHDM and the right sockets were naturally filled by blood clot (control). The animals were sacrificed at 3, 7, 14 and 21 days after surgery and upper maxillaries were processed for histological, morphometric and immunohistochemical analyses. DHDM was used to evaluate th...

243

A direct comparison between extracted tooth and filter-membrane biofilm models of endodontic irrigation using Enterococcus faecalis  

Endodontic restorations often fail due to inadequate disinfection of the root canal even though the antimicrobial irrigants used have been shown to be capable of killing the bacterium frequently implicated in this complication, Enterococcus faecalis (Ef). Extracted human teeth were root-prepared and filled with a liquid culture of Ef. Following incubation, the root canals were irrigated with 1% sodium hypochlorite (NaOCl), electrochemically activated water or saline control. Irrigation was modelled using an electronic pipette to deliver the solutions at a reproducible flow velocity. A series of parallel experiments employed a membrane biofilm model that was directly immersed into irrigant. Experimental conditions where contiguous between the extracted tooth model and biofilm model wherever...

244

Case presentation of florid cemento-osseous dysplasia with concomitant cemento-ossifying fibroma discovered during implant explantation.  

A 39-year-old African American woman presented for treatment of a symptomatic mandibular right first molar with a large, periapical radiolucency. After initial attempts at endodontic therapy, this tooth was ultimately extracted owing to unabated symptoms. The extraction site underwent ridge preservation grafting, implant placement, and restoration. After 26 months of implant function, the patient returned with clinical symptoms of pain, buccal swelling, and the sensation of a "loose" implant. This case report details a diagnosis of 2 distinct disease entities associated with the implant site, a cemento-ossifying fibroma and florid cemento-osseous dysplasia of the mandible. This diagnosis was determined from clinical, surgical, radiographic, and histopathologic evidence after biopsy and removal of the previously osseointegrated implant following postinsertion failure by fibrous encapsulation. Before implant therapy, it is essential to conduct a thorough radiographic evaluation of any dental arch with suspected bony lesions to prevent implant failure. PMID:22858018

245

Bone remodelling after regenerative procedures around implants placed in fresh extraction sockets: an experimental study in Beagle dogs  

Abstract Introduction: After a tooth extraction, the height of the buccal wall tends to decrease. The literature indicates that regenerative techniques (guided bone regenerative [GBR] techniques) have succeeded in improving the bone levels. Therefore, this experiment set out to compare the physiological bone remodelling in Beagle dog models after implant placement in a fresh extraction socket, with and without the application of regenerative procedure. Materials and methods: Five dogs were used in this study. Test and control sites were randomly selected. The experimental teeth (fourth pre-molar and first molar) were hemi-sected removing the distal roots and placing implants. Porcine bone was placed to fill the gap around the implant on the test sites and a reabsorbable membrane was used t...

246

Matrix Metalloproteinase-9 Expression in Alveolar Extraction Sockets of Zoledronic Acid–Treated Rats  

PurposeThe use of nitrogen-containing bisphosphonates (n-bis) is associated with necrosis of the jaws, also known as bisphosphonate-related osteonecrosis of the jaws (BRONJ); however, the pathophysiology is unknown. Matrix metalloproteinase-9 (MMP-9) expression is essential for normal bone healing and is also required for angiogenesis. N-bis alters MMP-9 expression in vitro and in vivo; therefore, we hypothesized that n-bis alters MMP-9 expression during oral wound healing after tooth extraction. Materials and MethodsA total accumulated dose of 2.25 mg/kg (n = 20) of Zoledronic acid (ZA) Zometa or saline (control, n = 20) was administered to Sprague–Dawley male rats. Next, both groups had maxillary molar teeth extracted. Rats were sacrificed at postoperative day 1, 3, 7, or 21. West...

247

Herniation of an Antral Polyp through an Oro-Antral Fistula  

Epulis, a discrete sessile or pedunculated mass of fibrous tissue on the gingiva caused by chronic inflammation, is a common lesion. However, other lesions may occasionally exhibit exophytic growth and they must be differentiated from epulis. A 38-year-old Japanese female noticed a pedunculated soft mass on the alveolar ridge of the right maxillary third molar shortly after extraction of the tooth. The mass, which had periods of exacerbation and quiescence, was excised under a tentative diagnosis of epulis. Because histopathology revealed edematous, inflamed antral mucosa with a covering of ciliated columnar epithelium, a final diagnosis of herniation of antral polyp through an oro-antral fistula was established. Although a rare occurrence, herniation of antral polyp should be included in the differential diagnosis of exophytic lesions on the maxillary molar alveolar ridge if there is a history of dental extraction at the concerned area.   

248

Tooth extraction decision model in periodontitis patients  

Abstract Objective: The purpose of this study was to build, around several types of input data, a decision analysis model for dental extraction strategy in periodontitis patients. Materials and methods: The decision analysis was based on the following scenario: a fictitious adult chronic periodontitis patient with no chief complaint, being referred to make a decision of extraction on one single tooth presenting a periodontal defect that may affect the decision-making process. A decision tree was used to identify the treatment options within the next 5 years. Scientific evidences were based on probabilities given by a literature analysis using a systematic approach. Clinical expertize was based on subjective utilities (SUs) assigned by an experts' panel. Expected utilities (EUs) were used t...

249

Postextraction maintenance of the alveolar ridge: rationale and review.  

Alveolar ridge resorption has long been considered an unavoidable consequence of tooth extraction and can be a significant problem in implant and restorative dentistry. Postextraction maintenance of the alveolar ridge minimizes residual ridge resorption and allows placement of an implant that satisfies both esthetic and functional criteria. Guided bone-regeneration techniques and the use of bone-replacement materials have been shown to enhance socket healing and potentially modify the resorption process. The prime indication for socket preservation is the prevention of alveolar-bone and soft-tissue collapse, which would cause unacceptable prosthesis esthetics. This review describes the rationale behind socket preservation, and the various techniques and materials used for extraction site grafting. PMID:22616214

250

A comparison of space closure rates between preactivated nickel-titanium and titanium-molybdenum alloy T-loops: a randomized controlled clinical trial  

The purpose of this study was to conduct a prospective randomized controlled clinical trial to evaluate the rate of space closure and tooth angulation during maxillary canine retraction using preactivated T-loops made from titanium-molybdenum alloy (TMA) and nickel-titanium (NiTi). Twelve patients (six males and six females) aged between 13 and 20 years who had upper premolar extractions were included, and each acted as their own control, with a NiTi T-loop allocated to one quadrant and TMA to the other using a split mouth block randomization design. The loops were activated 3 mm at each visit to deliver a load of approximately 150 g to the upper canine teeth. Maxillary dental casts, taken at the first and each subsequent monthly visit, were used to evaluate changes in extraction space and...

251

Inflammation and wound healing in cats with chronic gingivitis/stomatitis after extraction of all premolars and molars were not affected by feeding of two diets with different omega-6/omega-3 polyunsaturated fatty acid ratios  

Summary Feline chronic gingivitis/stomatitis (FCGS) is a painful inflammatory disease in cats. Extraction of teeth, including all premolars and molars, has been shown to be the therapy of choice in cats not responding sufficiently to home care (e.g. tooth brushing) and/or medical treatment (corticosteroids and/or antibiotics). In this study, we hypothesize that a cat food with an omega-6 polyunsaturated fatty acid (6 PUFA) to 3 PUFA ratio of 10:1 reduces inflammation of the FCGS and accelerates soft tissue wound healing of the gingiva after dental extractions, compared to a cat food with a 6:3 PUFA ratio of 40:1. The cats were fed diets with chicken fat and fish oil as sources of fatty acids. In one diet, part of the fish oil was replaced by safflower oil, resulting in two diets with 6:3 P...

252

Healing of Extraction Sockets Filled with BoneCeramic Prior to Implant Placement: Preliminary Histological Findings  

Abstract Background: Various grafting materials have been designed to minimize edentulous ridge volume loss following tooth extraction by encouraging new bone formation in healing sockets. BoneCeramic is a composite of hydroxyapatite and bta-tricalcium phosphate with pores of 100-500 microns. Purposes: The aim of this study was to evaluate bone regeneration in healing sockets substituted with BoneCeramic prior to implant procedures. Materials and Methods: Fifteen extraction sockets were substituted with BoneCeramic and 14 sockets were left to heal naturally in 10 patients (mean age 59.6 years). Biopsies were collected only from the implant recipient sites during surgery after healing periods ranging from 6-74 weeks (mean 22). In total, 24 biopsies were available; 10 from substituted and 14...

253

Er:YAG Laser Osteotomy Based on Refined Computer-Assisted Presurgical Planning: First Clinical Experience in Oral Surgery  

Objective: This case report was aimed at primary clinical experience concerning surgical extraction of a displaced tooth with the help of the Er:YAG laser based on refined computer-assisted presurgical planning. Methods: The case refers to the extraction of a displaced maxillary canine in a female patient. For the osteotomy, a pulsed Er:YAG laser was applied with pulse energy of 500 mJ, pulse duration of 250 sec and pulse frequency of 12 Hz. The fiber tip (1000 m) was kept with a 1-2 mm distance to the bone surface. Refined presurgical computer-assisted planning was performed with regard to minimization of bone loss, especially for the sake of preservation of the alveolar ridge. Based on a detailed three-dimensional (3D) reconstruction of the patient's anatomy, dynamical simulations of a b...

254

Multispectral near-IR reflectance and transillumination imaging of teeth.  

NIR imaging methods do not require ionizing radiation and have great potential for detecting caries lesions (tooth decay) on high-risk proximal and occlusal tooth surfaces and at the earliest stages of development. Previous in vitro and in vivo studies at 1300-nm demonstrated that high contrast reflectance and transillumination images could be acquired of caries lesions on tooth proximal and occlusal surfaces where most new decay is found. Water absorption varies markedly between 1200 and 1600-nm and the scattering properties of enamel and the underlying dentin have not been characterized in this region. Hyperspectral reflectance studies show lower reflectivity from sound enamel and dentin at NIR wavelengths with higher water absorption. The purpose of this imaging study was to determine which NIR wavelengths between 1200 and 1600-nm provide the highest contrast of demineralization or caries lesions for each of the different modes of NIR imaging, including transillumination of proximal and occlusal surfaces along with cross polarization reflectance measurements. A tungsten halogen lamp with several spectral filters and a Ge-enhanced CMOS focal plane array (FPA) sensitive from 400 to 1600-nm were used to acquire the images of caries lesions on extracted teeth. Artificial interproximal lesions were created on twelve tooth sections of 5 & 6-mm thickness that were used for transillumination imaging. Fifty-four extracted teeth with suspected occlusal lesions were also examined in both occlusal transillumination and reflectance imaging modes. Cavity preparations were also cut into whole teeth and filled with composite and used to compare the contrast between composite and enamel at NIR wavelengths. NIR wavelengths longer than 1400-nm are likely to have better performance for the transillumination of occlusal caries lesions while 1300-nm appears best for the transillumination of proximal surfaces. Loss of mobile water in enamel markedly reduced the transparency of the enamel at all NIR wavelengths. Significantly higher contrast was attained for reflectance measurements at wavelengths that have higher water absorption, namely 1460-nm. Wavelengths with higher water absorption also provided higher contrast of composite restorations. PMID:22025986

255

Effect of 10% and 15% Carbamide Peroxide on Fracture Toughness of Human Dentin In Situ.  

SUMMARY Purpose : Although damage to the structural integrity of the tooth is not usually considered a significant problem associated with tooth bleaching, there have been some reported negative effects of bleaching on dental hard tissues in vitro. More studies are needed to determine whether the observed in vitro effects have practical clinical implications regarding tooth structural durability. Objectives : This in situ study evaluated the effect of 10% and 15% carbamide peroxide (CP) dental bleach, applied using conventional whitening trays by participants at home, on the fracture toughness of dentin. Methods : Ninety-one adult volunteers were recruited (n ? 30/group). Compact fracture toughness specimens (approximately 4.5 × 4.6 × 1.7 mm) were prepared from the coronal dentin of recently extracted human molars and gamma-radiated. One specimen was fitted into a prepared slot, adjacent to a maxillary premolar, within a custom-made bleaching tray that was made for each adult participant. The participants were instructed to wear the tray containing the dentin specimen with placebo, 10% CP, or 15% CP treatment gel overnight for 14 nights and to store it in artificial saliva when not in use. Pre-bleach and post-bleach tooth color and tooth sensitivity were also evaluated using ranked shade tab values and visual analogue scales (VASs), respectively. Within 24-48 hours after the last bleach session, the dentin specimens were tested for fracture toughness using tensile loading at 10 mm/min. Analysis of variance, Kruskal-Wallis, ?(2), Tukey's, and Mann-Whitney U tests were used for statistical analysis. The level of significance was set at p<0.05 for all tests, except for the Mann-Whitney U tests, which used a Bonferroni correction for post hoc analyses of the nonparametric data (p<0.017). Results : The placebo, 10% CP, and 15% CP groups contained 30, 31, and 30 participants, respectively. Mean fracture toughness (+ standard deviation) for the placebo, 10% CP, and 15% CP groups were 2.3 ± 0.9, 2.2 ± 0.7, and 2.0 ± 0.5 MPa*m(1/2) respectively. There were no significant differences in mean fracture toughness results among the groups (p=0.241). The tooth sensitivity VAS scores indicated a significantly greater incidence (p=0.000) and degree of tooth sensitivity (p=0.049 for VAS change and p=0.003 for max VAS) in the bleach groups than in the placebo group. The color change results showed generally greater color change in the bleach groups than in the placebo group (p=0.008 for shade guide determination and p=0.000 for colorimeter determination). Conclusions : There were no significant differences in in situ dentin fracture toughness results among the groups. The results of this study provide some reassurance that dentin is not overtly weakened by the bleaching protocol used in this study. However, the lack of a statistically significant difference cannot be used to state that there is no effect of bleach on dentin fracture toughness. PMID:22934528

256

Patterning of Molar Tooth Roots in Mammals  

Tooth morphogenesis is regulated by reciprocal interactions between the dental epithelium and odontogenic mesenchyme. As tooth roots are fundamental structures of the tooth support system, the morphology and functions of the roots are very important. However, basic information on the morphology of tooth root patterning and the molecular mechanism of root morphogenesis is largely unavailable. Following tooth crown formation, the dental epithelium forms a double-layered Hertwig’s epithelial root sheath (HERS) derived from inner and outer enamel epithelium. Previous studies have reported that HERS plays an important role in tooth root development. Here, we report the correlation between the number of major cusps of the tooth crown and number of tooth roots of first molar and last premolar teeth in several extant mammals. We also discuss the molecular mechanism of tooth root patterning by introducing studies of mouse mutants and human syndromes associated with an abnormal molar morphology.   

257

The effects of varying degrees of allograft decalcification on cultured porcine osteoclast cells  

Purpose The healing process following tooth extraction apparently results in a pronounced resorption of the alveolar ridge. As a result, the width of alveolar ridge is reduced and severe alveolar bone resorption occurs. The purpose of this experiment is to clinically and histologically evaluate the results of using horse-derived bone mineral for socket preservation. Methods The study comprised 4 patients who were scheduled for extraction as a consequence of severe chronic periodontitis or apical lesion. The extraction was followed by socket preservation using horse-derived bone minerals. Clinical parameters included buccal-palatal width, mid-buccal crest height, and mid-palatal crest height. A histologic examination was conducted. Results The surgical sites healed uneventfully. The mean ridge width was 7.75 ± 2.75 mm at baseline and 7.00 ± 2.45 mm at 6 months. The ridge width exhibited no significant difference between baseline and 6 months. The mean buccal crest height at baseline was 7.5 ± 5.20 mm, and at 6 months, 3.50 ± 0.58 mm. The mean palatal crest height at baseline was 7.75 ± 3.10 mm, and at 6 months, 5.00 ± 0.82 mm. There were no significant differences between baseline and 6 months regarding buccal and palatal crest heights. The amount of newly formed bone was 9.88 ± 2.90%, the amount of graft particles was 42.62 ± 6.57%, and the amount of soft tissue was 47.50 ± 9.28%. Conclusions Socket preservation using horse-derived bone mineral can effectively maintain ridge dimensions following tooth extraction and can promote new bone formation through osteoconductive activities. PMID:11895288

258

Actitud terapéutica ante sacos foliculares de terceros molares incluídos/ Therapeutic approach to impacted third molar follicles  

Abstract in spanish El quiste dentígero o folicular es un quiste odontogénico del desarrollo. Está revestido por el epitelio del folículo dentario, y suele estar en relación con un diente permanente incluído. Presentamos el caso clínico de un paciente en el que se observa la aparición de un quiste dentígero a partir del saco folicular de un tercer molar incluído no exodonciado, y lo comparamos con la evolución de un cordal incluído y su saco folicular contralaterales en los que s (more) e realizó la exodoncia. El tratamiento definitivo del quiste dentígero asociado a un tercer molar incluído es quirúrgico, con la exodoncia de la pieza y enucleación del quiste. Los sacos foliculares mayores de 2 mm asociados a terceros molares incluídos evolucionan en numerosas ocasiones a quistes foliculares. Está indicada la exodoncia de dichos cordales para evitar la evolución a quiste dentígero. Abstract in english The dentigerous cyst or follicular cyst is a developmental odontogenic cyst. It is covered by the epithelium of the dental follicle, and it tends to be related to an impacted permanent tooth. The case report of a patient who was seen to develop a dentigerous cyst arising from the follicle of an impacted non-extracted third molar is presented. This is then compared with the evolution of the contralateral impacted third molar and its follicle that was extracted. The definit (more) ive treatment for a dentigerous cyst associated with an impacted third molar is surgical, the extraction of the tooth and enucleation of the cyst. Follicles measuring more+ than 2 mm and that are associated with impacted third molars often develop into follicular cysts. The extraction of these third molars is indicated in order to avoid the development of a dentigerous cyst

259

Evaluation of buccal alveolar bone dimension of maxillary anterior and premolar teeth: a cone beam computed tomography investigation.  

Purpose: Clinical guidelines suggest that a minimal buccal alveolar bone thickness of 1 to 2 mm is required to maintain the tissue architecture following tooth extraction and implant placement. The aim of this study was to evaluate the thickness of buccal alveolar bone at the maxillary first premolars and anterior teeth using cone beam computed tomography (CBCT). Materials and Methods: CBCT images of the maxillae of 43 implant patients were obtained. Two examiners manually measured the distance from the cementoenamel junction (CEJ) to the buccal alveolar bone crest and the thickness of the buccal alveolar bone at the crest, midroot, and apex of the maxillary first premolars and anterior teeth. The absence of bone and presence of radiographic artifacts were recorded. Average bone thicknesses were calculated and compared. Both parametric and nonparametric statistics were used to analyze the findings. Results: The median distance from the CEJ to the buccal alveolar bone crest was 2.79 mm, and measurements were similar among tooth positions. The median buccal alveolar bone thickness 1 mm apical to the alveolar bone was 1.13 mm in the premolar area and 0.83 mm for the anterior maxillary teeth. The median buccal alveolar bone thickness at the midroot was 1.03 mm in the premolar area and 0.70 mm for the other anterior maxillary teeth. Measurements of the buccal plate at 1 mm from the tooth apex were similar in all teeth positions, with a median thickness of 0.88 mm. Conclusions: The presence or absence of buccal alveolar bone can be discerned by CBCT evaluation. Few maxillary anterior teeth displayed buccal alveolar bone thickness greater than 1 mm. The implications for implant therapy must be fully discerned regarding tissue biotypes and dental implant outcomes. PMID:23189304

260

Enamel thickness in Asian human canines and premolars  

Dental enamel thickness continues to feature prominently in anthropological studies of ape and human evolution, as well as studies of preventative oral care and treatment. Traditional studies of enamel thickness require physical sectioning of teeth for linear and scaled measurements. Recent applications of microtomographic imaging allow scientists to employ larger and more diverse samples, including global samples of recent humans as well as fossil hominin teeth. Unfortunately, little is known about the degree of enamel thickness variation among human populations, particularly across the dentition. This study employed microtomography to virtually image, section, and quantify the average enamel thickness of a sample of clinically extracted Indonesian canine and premolar teeth. This virtual sample was compared to physically sectioned African and European teeth. The results demonstrate that average enamel thickness is similar among human dentitions; no significant differences were detected within tooth positions, which is surprising given developmental differences between European and African canines and premolars. When populations were combined, differences were found in average enamel thickness between maxillary and mandibular premolars, and between canines and premolars within both dental arcades. This finding is potentially due to differences in premolar morphology and a trend of increasing enamel thickness distally throughout the dentition. The finding of limited population variation within tooth positions and significant variation between tooth positions is consistent with previous two-dimensional and three-dimensional studies of human molar enamel thickness. Average enamel thickness in canines and premolars does not differ between the sexes in our sample, although male teeth tend to have larger enamel and dentine cross-sectional areas, enamel–dentine junction lengths, and bi-cervical diameters. Males have significantly greater dentine area and enamel–dentine junction length than females for maxillary canines and premolars. The results of this study suggest that enamel thickness values in mixed-populations of humans are appropriate for comparisons with fossil hominins.   

 
 
 
 
261

The design and development of surgical templates for premolar transplants in adolescents.  

Day PF, Lewis BRK, Spencer RJ, Barber SK, Duggal M. The design and development of surgical templates for premolar transplants in adolescents. International Endodontic Journal., 45, 1042-1052, 2012. ABSTRACT: The aim of designing and fabricating the surgical templates was to assist the surgical component of premolar transplantation, by establishing and replicating the root dimensions of the donor premolar tooth. The correct template could be used to assess the socket preparation (width and depth) prior to placement of the transplant in the recipient site, obviating the need to repeatedly try the donor tooth for fit at the recipient site, thereby minimising trauma to the periodontal ligament of the donor tooth. Seventy-five mandibular premolars and 50 maxillary second premolars were selected with varying stages of root development. All teeth had been extracted for orthodontic reasons. The root was measured for its length (maxL) and maximum (maxW) and minimum width (minW) with digital callipers from standardised reference points. These measurements were then used in the design of premolar transplant templates. The mean measurements for second maxillary premolars were maxL 14.6?mm (±1.7), maxW 8.3?mm (±0.5) and minW 4.9 (±0.3). The mean measurements for mandibular premolars were maxL 14.8 (±1.6), maxW 7.4 (±0.6) and minW 5.3 (±0.5). From these measurements, a range of maxillary second premolar and mandibular premolar templates have been fabricated. These figures also inform the multidisciplinary planning process for the space requirements at the donor site prior to transplantation. PMID:23039120

262

In vitro study comparing fracture strength recovery of teeth restored with three esthetic bonding materials using different techniques.  

Reattachment of the fractured fragment of a traumatized tooth (whenever available and usable) has become the treatment of choice in cases of uncomplicated crown fractures. Despite the presence of various bonding materials and techniques, laboratory data evaluating the biomechanical aspects of such procedures is largely lacking in the literature. The objective of this in vitro study was to evaluate the fracture strength recovery of incisors, following fragment restoration with three different techniques. A total of 90 extracted human maxillary central incisors were subjected to crown fractured under standard conditions. This was carried out by applying a compressive force from the buccal aspect of the clinical crown using a universal strength testing machine. The fractured teeth were equality distributed in three groups, defined on the basis of the technique used for reattachment: i) overcontour, ii) internal dentinal groove and iii) direct buildup. Each group was further subdivided into three subgroups on the basis of the intermediate restorative material used for reattachment, namely: i) hybrid composite (Filtek Z100 Universal Restorative, ii) nanocomposite (Filtek Z350) and iii) Ormocer (Voco Admira). Following reattachment, the crowns were re-fractured under standard conditions. The force required for fracture was recorded and was expressed as a percentage of the fracture strength of the intact tooth. The data was expressed as a percentage of the fracture strength of the intact tooth. The data was analyzed using two-way ANOVA and Bonferroni tests for pair-wise comparison. The results showed no statistically significant differences in fractures strength between the three groups (P > 0.05). However, comparison of the subgroups revealed statistically significant higher strength recovery percentages for the hybrid and the nanocomposite compared with the Ormocer material (P < 0.05). It was concluded that material properties have a significant influence on the success of reattachment procedures. PMID:21069110

263

Effects of resin luting agents and 1% NaOCl on the marginal fit of indirect composite restorations in primary teeth  

Abstract in english OBJECTIVE: The purpose of this study was to provide information regarding the marginal adaptation of composite resin onlays in primary teeth previously treated with 1% sodium hypochlorite (NaOCl) (pulp irrigant) using two different resin luting agents. MATERIAL AND METHODS: Forty extracted sound primary molars had their crowns prepared in a standardized machine and were randomly divided into 4 groups (n=10): G1 (1% NaOCl irrigation+EnForce); G2 (EnForce); G3 (1% NaOCl irr (more) igation+Rely X); G4 (Rely X). The onlays were made with Z250 composite resin on plaster models. After luting, the tooth/restoration set was stored in 100% relative humidity at 37ºC for 24 h and finished with Soflex discs. Caries Detector solution was applied at the tooth/restoration interface for 5 s. The specimens were washed and four digital photos of each tooth were then taken. The extents of the gaps were measured with Image Tool 3.0 software. The percentage data were submitted to a Kruskal-Wallis test (?=0.05). The Relative Risk test analyzed the chance of a gap presence correlated to each group. RESULTS: There were no statistically significant differences (p>0.05) among the groups. The relative risk test revealed that some groups were more apt to have a presence of gaps than others. CONCLUSION: Neither the 1% NaOCl treatment nor the resin luting agents caused any alterations in the dental substrate that could have influenced the marginal adaptation of composite onlays in primary teeth.

264

Buccal bone plate in immediately placed and restored implant with Bio-Oss(®) collagen graft: a 1-year follow-up study.  

OBJECTIVES: The aim of this study was to radiographically assess the vertical and horizontal alterations of buccal alveolar bone after the insertion of a post-extractive implant using Bio-Oss(®) Collagen graft. MATERIAL AND METHODS: The study was designed as a prospective study. Adult patients were eligible for the study if they needed one or more immediately inserted and immediately restored implant replacing teeth to be extracted within region 15-25. After the insertion, the buccal gap was carefully grafted using Bio-Oss(®) Collagen and the implant immediately restored. Cone-Beam Computed Tomography (CBCT) was performed immediately after surgery and a series of measurements were made to determine the dimension of the buccal bone plate and the void between implant and extraction socket. A second CBCT was taken and the measurements repeated after 12 months. RESULTS: Altogether, 69 patients were included in the study; a total of 69 implants were inserted. The study demonstrated that the extraction of a tooth and the immediate insertion of an implant together with an xenograft resulted in alterations of the vertical and horizontal dimension of the buccal bone plate (respectively, 25.6% and 29.3%). Nevertheless, the vertical and horizontal gap reduction was nearly complete (respectively, 99.3% and 99.1%) and the implant was normally in contact with buccal bone. CONCLUSIONS: Implant placement into extraction sockets can result in favorable radiological results even in the presence of evident alterations of the buccal bone wall. PMID:22882574

265

Three-year analysis of Tapered Screw-Vent implants placed into extraction sockets grafted with mineralized bone allograft.  

With clinicians placing more dental implants, it is becoming increasingly important to maintain bone volume after tooth extraction. This article reports the results of implants placed into extraction sites grafted with particulate mineralized bone allograft (Puros). A total of 313 extraction sites were grafted with mineralized bone graft during a 36-month period. A total of 252 Tapered Screw-Vent dental implants were placed into the grafted extraction sites after a 4- to 7-month healing period. All reentries revealed a bony hard structure acceptable for osteotomy preparation. A total of 244 of these implants have been restored with fixed prosthesis and 6 with removable overdentures for a total of 250 loaded implants. A total of 6 implants failed, which required their removal (2 implants before load and 4 after loading), resulting in a 97.6% implant success rate. We conclude that mineralized human allograft placed into extraction sites is clinically useful to maintain bone volume. This material provided a bony hard structure acceptable for implant placement with good success rates. PMID:16447901

266

Research of vision measurement system of the instruction sheet caliper rack  

This article proposes a method of rack measurement based on computer vision. It establishes a computer vision measurement system; the system consists of precision linear guide, camera, computer and other several parts. The entire system can be divided into displacement platform design system and image acquisition system two parts. The displacement platform system is that the linear guide campaigns driven by the driver controlled by the computer, to expand the scope of this measure realizing the measurement for the whole tooth. Image acquisition system is the use of computer vision technology to analysis and identification the capture images, the light source emitting light to the caliper rack, camerawork is to be the image which acquisitioned. Then input the images to the computer through the USB interface in order to the image analysis, such as Edge Detection, Feature Extraction and so on. And the detection accuracy reaches to sub-pixel level. Experiment with the rack modulus of 0.19894 instruction sheet calipers to measure, using image processing technology to realize the edge detection, and getting the edge of rack. Finally get the basic parameters of the rack such as p and s, and calculated individual circular pitch deviation fpt, total cumulative pitch deviation Fp, tooth thickness deviation fsn. Then comparison the measurement results with the Accretech S1910DX3. It turned out that the accuracy of this method can meet the requirements for the measurement of such rack. And the measurement method is simple and practical, providing technical support for the rack online testing.

267

Effect of light units on tooth bleaching with visible-light activating titanium dioxide photocatalyst  

This study evaluated the influence of different light sources on the efficiency of an office bleaching agent containing visible-light activating titanium dioxide photocatalyst (VL-TiO2) using an artificial discoloration tooth model. Extracted bovine teeth were stained by black tea. The CIE L*a*b* values were measured before and after nine consecutive treatments by the VL-TiO2-containing bleaching agent (TiON in Office, GC, Tokyo, Japan). A halogen light unit (CB; CoBee, GC) or an LED unit (G-light, GC) with two modes (blue and violet: GL-BV, blue: GL-B) were used to activate the bleaching agent in three groups (n=8). Brightness (?L) and color difference (?E) increased as bleaching repeated in all groups. Two-way ANOVA showed that both number of treatments and light sources significantly affected ?E (p<0.05). GL-BV showed better bleaching effect than GL-B. In measurement of irradiation spectra, CB showed a wide spectrum (380–530 nm), GL-B had a sharp peak at 470 nm and GL-BV showed an additional peak at 405 nm. It was concluded that the light source influenced the efficiency of the tooth bleaching with VL-TiO2.   

268

Maxillary osteonecrosis and spontaneous teeth exfoliation following herpes zoster.  

BACKGROUND: Reports of osteonecrosis and spontaneous tooth loss following herpes zoster infection of the fifth cranial are extremely rare. Only 39 previously recorded cases of post-zoster osteonecrosis have been found in the literature. The unusual feature of the case of interest to the dental surgeon is a rare complication of tooth exfoliation and maxillary osteonecrosis. CASE REPORT: This article reports a case of 52-year-old man with herpes zoster infection of the trigeminal nerve and related alveolar bone necrosis and teeth loss. The etiology and management of herpes zoster infection associated with destructive sequelae are discussed. DISCUSSION: Very few cases of osteonecrosis and spontaneous teeth exfoliation secondary to herpes zoster are found in the literature. The exact mechanism by which herpes zoster induces these destructive changes in the alveolar bone and teeth cannot be proposed. As Varicella zoster virus is an aneurotropic virus, the possible provoking factors may be the infection of the nerves innervating the periosteum or the chronic inflammatory changes in the form of adverse periodontal disease and delayed healing of the extraction sockets associated with compromised host resistance. PMID:22069058

269

Fusión de un tercer molar mandibular con un cuarto molar supernumerario/ Fusion of mandibular third molar with supernumerary fourth molar  

Abstract in spanish La fusión dental es la unión de dos gérmenes dentales normalmente separados, mientras que la geminación se define como el intento de división de un único germen dental. La fusión y geminación de molares es poco frecuente en la dentición permanente. Describimos un caso clínico de un tercer molar inferior derecho fusionado a un cuarto molar supernumerario en un paciente varón de 36 años que ha presentado repetidos episodios de pericoronaritis. Tras el estudio ra (more) diológico se realiza la exodoncia del cordal semiincluido bajo anestesia local. Llevamos a cabo una revisión bibliográfica al respecto. Abstract in english Dental fusion is the union of two tooth buds that normally are separated, while gemination is defined as an attempt by a single tooth bud to divide. The fusion and gemination of molars is uncommon in permanent teeth. We report a clinical case of a right lower third molar fused to a supernumerary fourth molar in a 36-year-old male patient with repeated episodes of inflammation. After the radiologic study, the semi-impacted third molar was extracted under local anesthesia. The literature was reviewed.

270

Resistance to horizontal forces of dowel and amalgam-core restorations: a comparative study.  

Four designs of amalgam-core anchorage were compared in a laboratory study for the inability to withstand the horizontal component of occlusal force. Amalgam cores were constructed for extracted teeth with either composite resin-cemented Dentatus dowels, or with Para-post or Flexi-post dowels cemented with phosphate cement. All the posts were of comparable length and diameter. These anchorage designs were compared with each other and to a self-threading (TMS) pin-retained amalgam core, by application of horizontal force and recording forces causing failure. Flexi-post-retained amalgam cores failed at a mean force of 36.5 (+/- 8.5) kg while Dentatus-retained and Para-post-retained cores failed at 41.7 (+/- 8.0) kg and 46.6 (+/- 11.4) kg, respectively. TMS-retained cores resisted forces up to a mean force of 53.5 (+/- 4.5) kg. Patterns of failure varied widely among these groups. Composite resin-cemented Dentatus dowels were retained in the tooth in nine out of ten samples, while none of the ten Flexi-post dowels and only one of the ten Para-post dowels did so. Tooth fracture on failure occurred in seven out of ten Flexi-post-retained cores, while only three out of ten of the Para-post-retained cores and none of the Dentatus dowel-retained cores presented this unrepairable type of failure. Possible reasons for these differences are discussed. PMID:3305840

271

Retentive properties of three post-core systems.  

The retention in root canals of Flexi-Posts, Para-Posts and Brasseler/Vlock-Posts was measured using tensile and compressive/shear forces. Forty-two extracted maxillary anterior teeth were embedded in self-curing acrylic resin and treated endodontically. Each root canal was prepared with the appropriate matching drills for the post-core system chosen. Each post-core was cemented in the canal with zinc phosphate cement. A tensile force was applied along the long axis of each tooth and the force needed to dislodge the post-core was recorded. There was no difference in retention between the small diameter posts, but the difference between the medium and the large diameter posts, however, was significant. In the medium diameter post group, the Flexi-Post was approximately twice as retentive as the other two post-core systems evaluated. In the second series of tests compressive/shear force was applied at an angle of 130 degrees to the long axis of the tooth. The retention difference between the small diameter posts was found to be statistically significant, Flexi-Posts being more retentive than Para-Posts and B/V-Posts. PMID:8185535

272

Relationship between Mandibular Nerve Block Anesthesia and Body Mass Index in Children/ Relación entre la Anestesia del Nervio Mandibular y el Índice de Masa Corporal en Niños  

Abstract in spanish El objetivo de este trabajo fue observar la relación entre el bloqueo anestésico efectivo (BAE) del nervio mandibular, inyectando 1,8 ml de lidocaína al 2% con epinefrina 1:100.000, en niños y su índice de masa corporal (IMC). Fue diseñado un estudio de cohorte prospectivo. Se seleccionó una muestra de 93 niños que se atienden en el Módulo Dental de JUNAEB de Frutillar entre abril y julio de 2011. Se registró edad, sexo, motivo de la exodoncia y tipo de diente ( (more) permanente o deciduo). Se calculó el IMC para cada niño, que fue categorizado en 2 cohortes de acuerdo al criterio de la OMS: “bajo peso - normal” (BPN) para aquellos con un IMC Abstract in english The aim of this study was to observe the relationship between the anesthetic block sucess (ABS) of mandibular nerve, by injecting 1.8 ml of lidocaine 2% with epinephrine 1:100,000, in children and their body mass index (BMI). A prospective cohort study was designed. A sample of 93 6-13 years children attended in JUNAEB Dental Module of Frutillar between April and July 2011. We recorded age, gender, reason for tooth extraction and tooth type (permanent or deciduous). BMI w (more) as calculated for each child and categorized into two cohorts of study according to WHO criteria: those with a BMI

273

Living in a Sweetie Culture: Scottish Parents' Difficulties in Maintaining Their Children's Oral Health  

Objective: To investigate the views and experiences of parents whose children have rampant tooth decay. Methods: In-depth, semi-structured interviews were carried out with 19 parents of varied age and social background whose children had been referred to Dundee Dental Hospital for assessment for dental extractions. Participants were encouraged to discuss their own and their child's dental experiences and their views on how the child developed rampant caries. The interview data was systematically coded using key theme headings, and summary charts were constructed to facilitate analysis. Results: The parents found it difficult to avoid sweets and giving their children sweet treats. They had limited knowledge of oral health maintenance which was poorly applied. These factors, combined with the difficulties of family life--in particular illness and life events--created circumstances in which their children experienced tooth decay. Conclusions: Parents find it difficult to restrict their children's sugar intake in an environment where sugary snacks are so readily available. More societal support in restricting children's sugar intake is of central importance. Parents would benefit from more sympathetic and explicit diet and toothbrushing messages tailored to their individual circumstances from those involved in the care of children's oral health. (Contains 1 table.)

274

Distribution of fluoride and magnesium concentrations in deciduous tooth enamel of children with cerebral palsy and Down syndrome  

BACKGROUND: Systemic disturbance during the fetal and postnatal periods in disabled children may affect the formation and mineralization of deciduous tooth enamel. AIM: To reveal differences in the status of mineralization in the surface and inner layers of deciduous tooth enamel between children with cerebral palsy (CP), those with Down syndrome (DS), and controls. METHODS: Using extracted deciduous teeth obtained from CP children (5 teeth), DS children (5 teeth), and control children (11 teeth), fluoride and magnesium concentrations, used as mineralization parameters, were measured in three regions of the enamel at different depths: the enamel surface (ES), neonatal line (NL), and dentino-enamel junction (DEJ). RESULTS: Fluoride concentration was significantly higher in the ES region than in the NL or DEJ region in all three groups. There was no significant correlation between type of disability and fluoride concentration. Magnesium concentration was significantly higher in the DEJ region than in the NL or ES region. A significant correlation was seen between type of disability and magnesium concentration. CONCLUSIONS: Magnesium concentration was significantly higher in DS children than in control children, suggesting that DS children undergo poorer mineralization. Magnesium concentration tended to be higher in CP children than in control children.   

275

High resolution charge-coupled device sensor vs. medium resolution photostimulable phosphor plate digital receptors for detection of root fractures in vitro.  

The aim of this study was to compare the diagnostic accuracy of a high resolution charge-coupled device (CCD) sensor and a medium resolution photostimulable phosphor (PSP) plate for detecting experimentally induced root fractures and further, to evaluate differences between images taken with various horizontal and vertical angles. Forty-seven extracted single-rooted human teeth mounted in a dry human skull were used in the experiment. The teeth were radiographed, before and after root fractures were induced, with two digital receptors: the Digora PSP system (approx. 8 lp mm(-1)) and the RVG-ui(TM), a CCD sensor with a high-resolution mode (15-20 lp mm(-1)). Four images were taken with each of the receptors of each tooth: one orthogonal exposure (O-images), one exposure with a vertical angle of 15 degrees by which the root was imaged elongated (L-images), and two eccentric exposures with a horizontal angle of 15 degrees mesially and distally. Three observers marked a fracture line if detected, in each image. Three sessions were held, one assessing the O-images, one the L-images, and one in which all four images of the same tooth were displayed simultaneously (X-images). The RVG-ui images obtained higher sensitivities than the Digora PSP images (P 0.05). It may be speculated that the difference in spatial resolution between the two digital systems accounts for the differences in their sensitivity. PMID:15660754

276

Maxillary cyst associated with an invaginated tooth: a case report and literature review.  

Dental invagination or dens in dente is a rare malformation with a widely varied morphology. Radiographically, the affected tooth shows an infolding of the enamel and dentin that can extend to within the pulp cavity and the root and sometimes to the root apex. It can occur in both primary and permanent teeth, and its prevalence is reported to be 1.7% to 10%. The dental anomalies observed in association with dental invagination include taurodontia, microdontia, supernumerary teeth, gemination, and dentinogenesis imperfecta. This article presents a clinical case in which a radiographic finding could be compatible with the presence of a nasopalatine or globulomaxillary cyst and a dens in dente. It was decided to extract the invaginated tooth, and by 15 days postextraction, the radiolucid area had completely disappeared. The complex surgery that would have been required to remove the patient's supposed cyst was thus avoided. Clinical and radiographic examination is suggested before making further decisions that could complicate treatment when a lesion is associated with other dental anomalies. PMID:12946069

277

Avoiding osseous grafting in the atrophic posterior mandible for implant-supported fixed partial dentures: a report of 2 cases.  

Bone atrophy occurs after tooth extraction in the posterior mandible, placing the mandibular canal and its neural, arterial, and venous contents closer to the osseous facial aspect and the coronal crest. This proximity places the structure in danger of damage when dental implants are surgically placed to support fixed or removable prostheses. Several options are available to treat these areas for implant-supported fixed and removable complete or partial dentures. Osseous grafting and ridge expansion are surgical options that enable acceptance of standard sized dental implants but have serious morbidities. Additionally, vertical osseous augmentation is not predictable at this time. Narrow diameter dental implants can be placed to avoid the mandibular canal, but some bone volume situations preclude this. Very wide and very short (6.5 × 5 mm) dental implants may be placed at an angle in atrophic sites to successfully support fixed partial dentures. An anterior guidance occlusal scheme may be used in maxillary dentate patients or group function in maxillary complete denture patients. A 100 micron occlusal relief in fixed partial dentures in dentate patients may be required to account for natural tooth intrusion and to prevent occlusal overload of the implant-supported partial denture. PMID:20925498

278

Management of paediatric sinonasal rhabdomyosarcoma  

Objectives: This study aims at analyzing the changes in gingival crevicular fluid (GCF) lactate dehydrogenase (LDH) activity during orthodontic movement. Methods: Twenty patients all requiring first premolar extractions were selected and treated with conventional straight wire mechanotherapy. Canine retraction was done using 125 g Nitinol closed coil springs. The maxillary canine on one side served as the experimental site while the contralateral canine served as the control. GCF was collected from the canines before initiation of retraction, then 1 hour after initiating canine retraction, followed by 1 day, 7 days, 14 days and 21 days. GCF LDH levels were estimated and compared with the control site. Results The results revealed significantly higher LDH levels on the 7th, 14th and 21st day at the sites where orthodontic force had been applied. The levels also showed a significant increase from 0 hour to the 21st day. Peak levels were seen on 14th and 21st day following initiation of retraction. Conclusions: The study showed that LDH could be successfully estimated in the GCF and its increased levels could indicate active tooth movement, which could aid the clinician in monitoring active orthodontic tooth movement. PMID:19393123

279

Scanning electron microscopic study of laser-induced morphologic changes of a coated enamel surface  

A low-energy Nd:YAG laser was used to irradiate extracted human teeth coated with a black energy-absorbent laser initiator in a study to determine the extent of the morphologic changes produced in the enamel surface. The laser initiator was applied to a cleaned enamel surface and irradiated at an energy output of 30 mJ or 75 mJ. Both energy levels produced morphologic changes of the surface. There was a sharp line of demarcation between the coated, irradiated area and the surrounding noncoated enamel surface. The scanning electron microscope view at the lower energy level showed that the surface had melted and reformed with numerous small, bubble-like inclusions. The 75 mJ energy level showed individual impact craters with shallow centers and raised edges containing numerous pores and large, bubble-like inclusions. Etching is a dental procedure in which an acid is normally used to remove a thin outer layer of the tooth structure. This is necessary to create a roughened, irregular surface in order to provide mechanical retention for dental restorative materials. The changes produced by the laser in this study suggest a simple, effective, and controlled method of etching the enamel surface of a tooth by altering its surface characteristics.

280

[Castleman's disease].  

CASE REPORT: A 25-year-old patient with fever, dysphagia, and reduced general condition was referred to our department by his dentist after 1 week of antibiotic therapy. He presented with a painful palpable mass in the right lower jaw that had developed 2 weeks before. The orthopantomogram showed a caries and periapical lesion at the right lower wisdom tooth. During extraction of the tooth and putative intra- and extraoral abscess incision, no pus could be drained and the mass persisted. CT scans then revealed lobulated soft tissue masses on both sides of the neck with the main focus on the right side. In an additional operation with excision of the mass, Castleman's disease of the hyaline vascular type was diagnosed. HISTOPATHOLOGIC FINDINGS: Staging could not detect further pathological findings and the patient's postoperative general condition improved continuously. The histological features of the hayline vascular type of Castleman's disease were characterized by multiple germinal centers surrounded by circumferentially arranged layers of small lymphocytes interconnected by a prominent vascular stroma with occasional plasma cells ("onion skin"). CONCLUSION: Castleman's disease is a rare and yet poorly understood disease, characterized by inhomogeneous growth of lymphoid tissue. Mostly benign it remains a diagnostic challenge before histological investigation. In unclear submandibular swellings and neck lumps assumed to be an abscess, this rare differential diagnosis must be considered. Facing recurrence and potential for malignancy, follow-up of the patients over several years is necessary. PMID:15647952

 
 
 
 
281

Cone beam computed tomography evaluations of marginal alveolar bone before and after orthodontic treatment combined with premolar extractions.  

Using cone beam computed tomography (CBCT) we investigated the distance between the cemento-enamel junction (CEJ) and the marginal bone crest (MBC) at buccal, lingual, mesial, and distal surfaces of incisors to first molars in adolescents before (baseline) and after extractive orthodontic treatment (study end point). Patients with Class I malocclusion, crowding and an overjet of ? 5 mm were examined with a CBCT unit using a 60 × 60-mm field of view and a 0.125-mm voxel size. Large differences in marginal bone height were found at baseline, particularly between tooth surfaces. There was a slight correlation between age and CEJ-MBC distance. From baseline to the study end point, large bone-height changes among teeth and tooth surfaces could be seen. Lingual surfaces, followed by buccal surfaces, showed the largest changes. Eighty-four per cent of lingual surfaces of mandibular central incisors exhibited a bone-height decrease of > 2 mm. The bone-height decrease was larger at lingual surfaces in the mandible than in the maxilla, and larger in girls (mean=1.8 mm) than in boys (mean=1.5 mm). Fewer than 1% of proximal surfaces exhibited changes of > 2 mm. It is unknown whether the changes in marginal bone height are transitory. A high-quality CBCT technique may help to determine this by providing a deeper insight into the long-term side effects of orthodontic treatment. PMID:22607336

282

Fluorine analysis of human dentin surrounding resin composite after fluoride application by ?-PIGE/PIXE analysis  

The use of fluoride for the prevention of caries is based on the transformation of hydroxylapatite to fluoroapatite in the presence of fluoride ions, thereby strengthening tooth structure. Adhesion of dentin and resin composite (tooth-colored restoration material) requires a dentin bonding system, since resin composite is not able to adhere to dentin directly. Demineralization of dentin by acid etching is an important step in the dentin bonding system, however, demineralization also introduces weaknesses in tooth structure. If the demineralized dentin could be strengthened by the application of fluoride, then the dentin-resin composite bond strength might also improve. To test this hypothesis, the present study evaluated the influence of fluoride applications on the strength of the dentin-resin composite bond by (1) tensile strength testing analyses, (2) SEM analyses of tooth structure, and (3) detection of calcium (Ca) and fluorine (F) distribution patterns by micro proton-induced X-ray emission (?-PIXE) and micro proton-induced gamma-ray emission (?-PIGE) analyses conducted at the Takasaki Ion Accelerators for Advanced Radiation Application (TIARA) at the Takasaki Advanced Radiation Research Institute (TARRI).In this study, the dentin in extracted human molars was exposed by grinding and the dentin was etched with 35% phosphoric acid. Fluoride was applied at two concentrations, 0.022% (100 ppm F) and 2.21% (10,000 ppm F) NaF solution, for two time periods, 30 and 60 s, prior to bonding the resin composite with the treated dentin. Controls were prepared in the same manner, but without the fluoride application. Bond strength was measured with a micro-tensile testing unit, and the fluorine and calcium distributions at the interface between dentin and resin composite were detected by ?-PIGE and ?-PIXE analysis, respectively.Results indicate that the 10,000 ppm F applications resulted in higher bond strengths than observed in either the 100 ppm F applications or the control group. In addition, PIGE analyses showed high concentrations of fluorine in the hybrid bonding layer of the 10,000 ppm F samples, suggesting that the fluorine contributes to the strength of the dentin-resin composite bond. Detection of fluoroapatite within the hybrid bonding layer suggests that bond strength involves remineralization processes.

283

Adipose Tissue-Derived Stem Cell in Vitro Differentiation in a Three-Dimensional Dental Bud Structure  

Tooth morphogenesis requires sequential and reciprocal interactions between the cranial neural crest–derived mesenchymal cells and the stomadial epithelium, which regulate tooth morphogenesis and differentiation. We show how mesenchyme-derived single stem cell populations can be induced to transdiff...

284

Nutrition  

... citrus fruits can have acidic effects on tooth enamel, too, so eat them as part of a ... in dental health, by protecting and rebuilding tooth enamel. Fruits and vegetables are good choices for a ...

285

NASATECHNICAL NASA TM X-68117 DESIGN ANALYSIS FOR A ...  

nutating plate type drive system for a 3500 horse- power" helicopter ... tooth width at working depth line, in. I moment of ... input shaft, the nutating plate makes one nutation and advances .... The tooth bending stress can be calculated using the ...

286

Restoration of noncarious tooth defects by dentists in The Dental Practice-Based Research Network  

The authors conducted a study to quantify the reasons for restoring noncarious tooth defects (NCTDs) by dentists in The Dental Practice-Based Research Network (DPBRN) and to assess the tooth, patient and dentist characteristics associated with those reasons.

287

Repairing Children's Teeth  

... caries) Trauma — a broken or cracked tooth Poor development, so that a tooth may be too small or improperly shaped Endodontic therapy (pulpotomy or root canal therapy ) Change in color Restoring Children's Primary ...

288

Tooth  

... of four dental tissues. Three of them—enamel, dentin and cementum—are hard tissues. The fourth tissue— ... a Tooth Enamel. Hard calcified tissue covering the dentin in the crown of tooth. Because it contains ...

289

Aplicación de matriz de hueso humano desmineralizado en el procedimiento quirúrgico de la fusión dentaria: Reporte de un caso/ Aplication of demineralized human bone matrix in the surgical dental fusion treatment: Report of a case  

Abstract in spanish El propósito del presente trabajo es dar a conocer una alternativa quirúrgica en el tratamiento de las fusiones dentarias mediante la colocación de matriz de hueso humano desmineralizado (MHHD) (Grafton® Putty, New Jersey Eatotown, Osteotech), luego de la separación y exodoncia del diente fusionado al permanente. La fusión de los dientes es una anomalía dentaria de unión, que consiste en la unión de dos gérmenes dentarios en desarrollo, pudiendo suceder en cualq (more) uiera de los estadios de evolución del germen dental a partir de la lámina dentaria o en períodos más avanzados del proceso de diferenciación. Para el tratamiento, se utilizó un aloinjerto de MHHD con propiedades osteoinductivas y osteoconductivas, que además posee varios factores de crecimiento óseo, lo cual permitió el crecimiento gradual de nuevo hueso, que corrigió los defectos óseos acarreados post exodoncia y cubrió la pared distal expuesta del diente permanente remanente. Para el control clínico se realizaron radiografías periapicales y panorámicas. Se concluyó que la separación quirúrgica y exodoncia del diente con menor similitud anatómica al contralateral y posterior colocación de MHHD, representa una alternativa en el tratamiento quirúrgico de las fusiones dentarias. Abstract in english The purpose of this work is to present a surgical alternative in the treatment of the dental fusions through the placement of demineralized human bone matrix (DHBM) (Grafton Putty)*, immediately after the separation and extraction of the fused tooth to the permanent one. The dental fusion is a dental anomaly of union, that consists in the union of two dental germs during development. It could happen at any of the dental germ evolution stages from the dental sheet or from (more) more advanced processes of differentiation. For the clinical treatment, an allograft of DHBM with osteoinductive and osteoconductive properties was used. This had several factors of bone growth, it allowed the gradual growth of a new bone that helped to correct the bone defects post-extraction and to cover the exposed distal wall of the remaining permanent tooth. The clinic evaluation and the periapical and panoramic radiographies images were used for the clinical control. It can be concluded that the surgical separation and the extraction of the tooth with less anatomical likeness to the contralateral and the placement of the DHBM, represent a surgical treatment alternative of the dental fusion.

290

Squeezing into differentiation.  

The earliest steps in tooth development depend on signaling interactions that result in the condensation of mandibular mesenchyme into the tooth bud. Reporting in this issue of Developmental Cell, Mammoto et al. (2011) find that chemotactic signals coordinate condensation and that the compressive force generated is sufficient to induce tooth bud gene expression. PMID:22014519

291

Squeezing into Differentiation  

The earliest steps in tooth development depend on signaling interactions that result in the condensation of mandibular mesenchyme into the tooth bud. Reporting in this issue of Developmental Cell, Mammoto et al. (2011) find that chemotactic signals coordinate condensation and that the compressive force generated is sufficient to induce tooth bud gene expression.

292

Supernumerary teeth: Report of four unusual cases  

Supernumerary tooth denotes duplication of tooth in the normal series. It is a developmental anomaly and has been argued to arise from multiple etiologies. These teeth may remain embedded in the alveolar bone or can erupt into the oral cavity. The supernumerary tooth might cause esthetic and/or func...

293

Intracranial supernumerary tooth  

Case report of an accidentally diagnosed supernumerary tooth in the superior orbital fissure. Computed tomography (CT) contributed with a more precise localization of the tooth being situated between the orbit and the brain. CT also showed that there was no cyst or other pathological process around the supernumerary tooth, which is plausible and frequently reported in the literature.

294

Modelling dependencies and couplings in the design space of meshing gear sets  

This work presents a design methodology based on the combination of a set of compatibility equations for determining nominal tooth and cutter geometry and a set of tooth contact analysis equations for determining modified tooth surfaces and motion transmission laws. Both have been shown separately t...

295

Msx1 Mutations: How Do They Cause Tooth Agenesis?  

Mutations in the transcription factors PAX9 and MSX1 cause selective tooth agenesis in humans. In tooth bud mesenchyme of mice, both proteins are required for the expression of Bmp4, which is the key signaling factor for progression to the next step of tooth development. We have previously shown tha...

296

Characterization of root surface periodontal ligament following avulsion, severe intrusion or extraction: preliminary observations.  

This study employed novel topographic and histological techniques to assess remaining periodontal ligament (PDL) in a convenience sample of avulsed and intruded human permanent incisors and extracted premolars. Seventeen human teeth (eight avulsed, five severely intruded and four uninjured extracted) were evaluated for the distribution and physical characteristics of adherent root surface PDL. The topographic distribution of PDL was assessed by staining roots with malachite green and determining the proportion of remaining PDL within selected regions on four aspects of each tooth. In order to characterize mechanical damage to PDL, serial transverse sections of roots were stained with hematoxylin and eosin and examined at magnifications of 40x to 800x. The sections were photographed and imaging software was used to calculate the percentage of remaining PDL in the circumference of each root section. Topographic analysis demonstrated that 54% of the PDL remained on roots of avulsed and severely intruded incisors and 36% of the PDL remained on the extracted single-rooted premolars. Examination of serial transverse root sections revealed that 58% of the PDL remained on roots of avulsed or severely intruded incisors and 54% on extracted premolars. Avulsed and severely intruded incisors demonstrated similar amounts of retained PDL. In both injuries, almost half of the root surface was denuded of PDL. PMID:18721338

297

Bucco-lingual bone remodeling around implants placed into immediate extraction sockets: a case series  

Background: Bisphosphonate-induced osteonecrosis of the jaw (BONJ) is a frequently reported complication. The aim of this study was to investigate the clinical and histopathological presentation of BONJ with the Hounsfield score and to evaluate the reliability of the score for determining necrosis in an animal model. Material/Methods: Eighty rats were prospectively and randomly divided into two groups of 40 each: a control group and an experimental group. Half of the animals from each group underwent extraction of the left mandibular molars, and the other half underwent extraction of the left maxillary molars under pentobarbital-induced general anesthesia. All animals were euthanized 28 days after tooth extraction. Maxillae and mandibles were extracted, cone beam computed tomography (CBCT) was performed, and Hounsfield scores were evaluated. Results: The Hounsfield scores of the experimental group were found to be compatible with chronic osteomyelitis and periosteal reactions. The Hounsfield scores of the control group were compatible with a healthy healing period. Conclusion: In light of these results, both cone beam computed tomography (CBCT) and the Hounsfield Units (HU) evaluations together are thought to be efficient in the diagnosis of BONJ. PMID:12666717

298

Secondary closure of an extraction socket using the double-membrane guided bone regeneration technique with immediate implant placement  

Purpose Immediate implantation presents challenges regarding site healing, osseointegration, and obtaining complete soft-tissue coverage of the extraction socket, especially in the posterior area. This last issue is addressed herein using the double-membrane (collagen membrane+high-density polytetrafluoroethylene [dPTFE] membrane) technique in two clinical cases of posterior immediate implant placement. Methods An implant was placed immediately after atraumatically extracting the maxillary posterior tooth. The gap between the coronal portion of the fixture and the adjacent bony walls was filled with allograft material. In addition, a collagen membrane (lower) and dPTFE membrane (upper) were placed in a layer-by-layer manner to enable the closure of the extraction socket without a primary flap closure, thus facilitating the preservation of keratinized mucosa. The upper dPTFE membrane was left exposed for 4 weeks, after which the membrane was gently removed using forceps without flap elevation. Results There was considerable plaque deposition on the outer surface of the dPTFE membrane but not on the inner surface. Moreover, scanning electron microscopy of the removed membrane revealed only a small amount of bacteria on the inner surface of the membrane. The peri-implant tissue was favorable both clinically and radiographically after a conventional dental-implant healing period. Conclusions Secondary closure of the extraction socket and immediate guided bone regeneration using the double-membrane technique may produce a good clinical outcome after immediate placement of a dental implant in the posterior area.

299

Immediate provisionalization of dental implants placed in fresh extraction sockets using a flapless technique.  

The aim of this clinical study was to evaluate the 24-month clinical outcomes of immediate provisionalization of dental implants placed in fresh extraction sockets using a flapless technique. Fifteen patients were included under strict inclusion and exclusion criteria. All patients required one or two teeth to be extracted for lesions with a hopeless prognosis in the maxillary monoradicular or first premolar region. Twenty implants were placed immediately after tooth extraction, and immediate provisionalization was performed. Sixteen implants had a diameter of 5 mm, and four implants had a diameter of 3.80 mm, all with a 13-mm length. After 24 months of follow-up, a cumulative survival rate of 100% was reported for all implants. Modified Bleeding Index (mBI), modified Plaque Index (mPI), probing depth (PD), marginal gingiva level (MGL), and keratinized mucosa (KM) remained stable for up to 24 months. Mean MGL at 24 months was 0.22 ± 0.15 mm; no significant changes occurred in MGL between baseline and 24 months. Mean KM remained stable from baseline to 24 months. At 24 months, a mean bone loss of 0.83 ± 0.52 mm was measured. The results of this study indicate that flapless surgery for immediately provisionalized implants placed in fresh extraction sockets provides soft tissue and marginal bone maintenance for up to 24 months of follow-up. PMID:22254223

300

Is autologous platelet concentrate beneficial for post-extraction socket healing? A systematic review.  

The aim of this systematic review was to assess if the use of autologous platelet concentrates may be beneficial to the healing of extraction sockets. Medline, Embase and Cochrane Central Register of Controlled Trials were searched using a combination of specific search terms. Hand searching of the relevant journals and of the bibliographies of reviews was also performed. Prospective comparative studies evaluating the effect of a platelet concentrate on fresh extraction sockets were included. Outcome variables related to hard and soft tissue healing, aesthetics and postoperative discomfort were considered. A methodological study quality assessment was made. The initial search yielded 425 articles, eight were finally included. 207 tooth extractions (104 tests and 103 controls) in 115 patients were evaluated. The articles provided a broad range of variable outcomes to assess the regenerative potential of platelet concentrate and its possible benefits to the treatment. Favourable effects on hard and soft tissue healing and postoperative discomfort reduction were often reported. A large heterogeneity was found regarding study design, sample size, surgical techniques and methods for preparing platelet concentrates. Standardization of experimental design is needed in order to detect the true effect of platelet concentrates in regenerative procedures of extraction sockets. PMID:21602028

 
 
 
 
301

Biphasic alloplastic graft used to preserve the dimension of the edentulous ridge: an experimental study in the dog.  

BACKGROUND: Loss of teeth results in marked qualitative and quantitative alterations of the alveolar process at the edentulous site. It was observed that a graft comprised of bovine bone mineral placed in the fresh extraction socket delayed tissue modeling, but preserved the dimension of the ridge at edentulous sites. OBJECTIVE: To analyze the influence of a biphasic synthetic graft on tissue modeling and remodeling during healing of extraction wounds. MATERIAL AND METHODS: Five beagle dogs were used. Two premolars in the maxilla and two in the mandible were included. Full thickness flaps were elevated and the distal roots were removed. An alloplastic graft (BPCAP; ?-TCP core coated with nanocrystalline biomimetic hydroxyapatite) embedded in porcine collagen was placed to fill the fresh extraction socket of the premolar sites. Flaps were replaced to cover the entrance of the extraction sockets during early healing. The extraction and grafting procedures were scheduled to allow for the study of 1, 2, and 3 months socket healing. The biopsies from the maxillary sites were decalcified, embedded in paraffin, and stained to allow the study of various aspects of hard tissue formation. The biopsies from the mandibular sites were processed for ground sectioning and used to evaluate alterations of ridge dimensions after 3 months of socket healing. RESULTS AND CONCLUSION: It was documented that the biphasic alloplastic graft did not undergo marked resorption during tissue modeling and remodeling, but allowed large amounts of bone to form within the post-extraction site. Grafting the experimental sites with this biomaterial furthermore counteracted ridge resorption that otherwise occurs following tooth extraction. PMID:22804845

302

Socket preservation using bovine bone mineral and collagen membrane: a randomized controlled clinical trial with histologic analysis.  

After tooth extraction, varying amounts of bone resorption occur because of qualitative and quantitative changes at the edentulous site of the alveolar process. The aims of this randomized controlled clinical trial were (1) to compare the postextraction changes in residual ridge dimensions during spontaneous healing with those during socket preservation, (2) to analyze the histologic and histomorphometric aspects of the grafted sockets, and (3) to compare probing procket depth (PPD) and clinical attachment level (CAL) changes at teeth adjacent to extraction sites. Forty-eight teeth were extracted from 41 patients referred for extraction of 1 or more maxillary or mandibular premolars or molars. The edentulous sites were randomly assigned to the control (EXT, extraction alone) or experimental groups (SP, extraction and socket preservation). In the SP group, the sockets were filled with bovine bone mineral and covered with porcine collagen membrane. At baseline and after 4 months, PPD, gingival recession (REC), and CAL were measured at teeth adjacent to the edentulous sites. The changes in ridge dimensions from baseline to 4 months were assessed on dental casts. At 4 months, bone was harvested from the grafted areas in the SP group and the edentulous areas in the EXT group. PPD, REC, and CAL were comparable between groups. However, from baseline to 4 months, the SP group showed significantly less reduction in ridge width (1.04 ± 1.08 mm vs 4.48 ± 0.65 mm, P < .001) and height (0.46 ± 0.46 mm vs 1.54 ± 0.33 mm, P < .001). Histologically, the grafted sockets exhibited various stages of bone maturation and formation without inflammatory responses. No significant difference in the mineralized and nonmineralized fractions was noted between the groups. Socket preservation using bovine bone mineral and porcine collagen membrane considerably limits the amount of horizontal and vertical bone resorption when compared with extraction alone. PMID:22577648

303

The role of cell surface markers and enamel matrix derivatives on human periodontal ligament mesenchymal progenitor responses in vitro  

Periodontitis is a chronic-, infectious-disease of the human periodontium that is characterized by the loss of supporting tissues surrounding the tooth such as the periodontal ligament (PDL), cementum and alveolar bone. Regeneration of the periodontium is dependent on the participation of mesenchymal stem/stromal cells (MSC) resident in the PDL. Enamel matrix derivative (EMD), an extract from immature porcine enamel rich in amelogenin protein but that also contain bone morphogenetic protein (BMP), is used to treat periodontal defects. The effects of EMD on MSC cells of the PDL are not well characterized. In this in vitro study, we identify PDL progenitor cells from multiple individuals and demonstrate that EMD stimulates them. We show that the effect of EMD on cell proliferation and migrat...

304

Computed online determination of life-long mean index values for carious, extracted, and/or filled permanent teeth  

Objective. The purpose of this study was to develop and test a data-mining system for the online determination of mean DS, M, and FS or DMFS values per subject at different ages from electronic patient records at two health centers to see if there are north-south differences in oral health in Finland. Material and methods. The mean index values were determined at two health centers using the codes of dental charts and progress notes of electronic dental records during the digital era of more than 10 years in a total of 153,619 subjects of all ages. Extracted teeth, as well as sound, carious, and restored tooth surfaces, were recorded from the dental charts. Treatments were then additionally registered from progress notes of the records when performed. Results. The cumulative DS and FS valu...

305

Midline correction by asymmetric reciprocal torque: a pilot study  

Objective Can we correct dental midline discrepancies by systematic torque bends on all canines and premolars without extraction and mesiodistal tooth movement? Patients and methods Eight orthodontic patients (4 males, 4 females, mean age 31 years) presented a dental midline discrepancy of 2â??4 mm, moderate deviation of the chin, no skeletal asymmetry, and a horizontal orientation of the occlusal plane in the frontal aspect. On the side where the mandible was shifted medially, asymmetric torque bends moved the antagonist canine and both premolar crowns buccally, while palatal crown torque was used on the maxillary canine and premolars on the other side. Lingual crown torque corrected the medially shifted canine and premolars in the mandibular dental arch, and buccal crown torque the l...

306

Effect of Er:YAG Laser Irradiations on Shear Bond Strength of Three Self-Adhesive Resin Cements to Dentin  

Abstract Objective: The purpose of this study was to evaluate the influence of Er:YAG laser irradiation on shear-bond strength of self-adhesive resin cements to dentin. Background data: Different laser-irradiation settings are used for dentin-surface pretreatment, which may affect the bond strength of resins. Methods: Fourty-five extracted third molars were selected, sectioned in a mesiodistal direction, and 90 tooth slabs were obtained. The teeth were ground to expose the dentinal hard tissue with 320- and 600-grit silicon carbide disks. The specimens were randomly assigned to nine groups (n???=???10). Surfaces for each group were laser irradiated with 30???Hz/70???mJ (2.1???W), 30???Hz/160???mJ (4.8???W), or non-irradiated (control) for each resin cement (SmartCem2, RelyX Unicem, Multili...

307

Synergistic Effect of Microbubble Emulsion and Sonic or Ultrasonic Agitation on Endodontic Biofilm in Vitro  

IntroductionIrrigation dynamics and antibacterial activity determine the efficacy of root canal disinfection. Sonic or ultrasonic agitation of irrigants is expected to improve irrigation dynamics. This study examined the effects of microbubble emulsion (ME) combined with sonic or ultrasonic agitation on irrigation dynamics and reduction of biofilm bacteria within root canal models. MethodsTwo experiments were conducted. First, high-speed imaging was used to characterize the bubble dynamics generated in ME by sonic or ultrasonic agitation within canals of polymer tooth models. Second, 5.25% NaOCl irrigation or ME was sonically or ultrasonically agitated in canals of extracted teeth with 7-day-grown Enterococcus faecalis biofilms. Dentinal shavings from canal walls were sampled at 1 mm and 3...

308

Furcation involvement in posterior teeth.  

This article presents two cases in which different treatments were used for mandibular molars with furcation lesions. In the first case, a conventional amputation treatment of the distal root was performed to save the mesial root as a terminal tooth, which was used as a partial denture abutment. The second case describes a relatively new technique in which a root perforation was filled with graft material (synthetic bioglass) and covered with a resorbable membrane to treat an iatrogenic furcation lesion adjacent to the mesial root. Twelve months after surgery, periapical radiographs of both treated cases showed increased bone density. Follow-up in both cases--30 months in the first case and 12 months in the second--showed no pathological recurrence or clinical dysfunction. Root amputation may provide an alternative to extraction in periodontally involved molars. Synthetic bone replacement materials combined with guided tissue regeneration may also help to correct osseous defects incurred by recent furcation perforations with associated bone loss. PMID:10649956

309

Ten-year longitudinal clinical evaluation of a visible light cured posterior composite resin.  

Using modified USPHS criteria, we evaluated annually for ten years 91 cases restored with visible light cured posterior composite resin LFP (Base resin: UDMA; filler: micro crushed type, alumino-silicate, barium glass and silica, 85 wt%, 74 vol%). The 91 cases restored with LFP decreased to 68 in ten years. Of the 23 cases that were lost, one resulted from a pulpal reaction immediately following restoration, four were extracted owing to periodontal disease or extrusion of third molars, two became abutments owing to loss of an adjacent tooth, eight had recurrent caries, and eight were lost owing to caries on a surface having no relationship to the composite resin restoration. Because we observed comparatively little wear, good marginal adaptability, and no discoloration, we concluded that the ten-year clinical success of LFP was on the whole very good, and that this resin has adequate clinical merit as a restorative material for posterior teeth when restricted to restorations covering comparatively small areas. PMID:8940551

310

Microtomography evaluation of dental tissue wear surface induced by in vitro simulated chewing cycles on human and composite teeth/ Valutazione microtomografica dell’usura dentale superficiale indotta da cicli di masticazione simulata in vitro su denti umani e in composito  

Abstract in english In this study a 3D microtomography display of tooth surfaces after in vitro dental wear tests has been obtained. Natural teeth have been compared with prosthetic teeth, manufactured by three different polyceramic composite materials. The prosthetic dental element samples, similar to molars, have been placed in opposition to human teeth extracted by paradontology diseases. After microtomography analysis, samples have been subjected to in vitro fatigue test cycles by servo- (more) hydraulic mechanical testing machine. After the fatigue test, each sample has been subjected again to microtomography analysis to obtain volumetric value changes and dental wear surface images. Wear surface images were obtained by 3D reconstruction software and volumetric value changes were measured by CT analyser software. The aim of this work has been to show the potential of microtomography technique to display very clear and reliable wear surface images. Microtomography analysis methods to evaluate volumetric value changes have been used to quantify dental tissue and composite material wear.

311

Lymphomatoid Granulomatosis Presenting with Gingival Involvement in an Immune Competent Elderly Male  

Lymphomatoid granulomatosis (LYG) represents a B cell lymphoproliferative disorder that appears to be driven by infection of the lesional cells by Epstein???Barr virus (EBV). Although not a common condition, the overwhelming majority of cases affect the lungs and mediastinal lymph nodes. Oral mucosal involvement has been documented in only one other report. We describe an 82-year-old man who developed a chronic oral ulcer following extraction of a mandibular molar tooth. Biopsy of the ulcer identified large atypical mononuclear cells that had a B cell immunophenotype and were associated with the walls of several arterioles in the sample. In situ probes for EBV-encoded small RNA showed prominent labeling of these large cells, suggesting the possibility of LYG. Imaging studies identified med...

312

Age-related peculiarities of tooth enamel as a natural EPR biodosimeter  

The influence of age on tooth enamel as an EPR dosimeter has been investigated using a big collection of teeth extracted from several tens of persons living in different regions of Ukraine. The study was focused on two groups of teeth. The first one represented the urban population while the second corresponded to residents of rural settlements. Age dependences of two above groups were quite different: for example, doses for the 65-75 year age group were approximately 200 mGy higher for urban population compared to habitants of rural settlements. This effect was explained by contribution of medical X-ray exposure: the comparison of corresponding lingual and buccal doses revealed the more frequent presence of X-ray dose for urban population. Another observed effect was the difference between average intensities of native signals for two studied groups. At present time, no correlation with age was seen for this effect.

313

Three-dimensional ultrashort echo magnetic resonance imaging of orthodontic appliances in the natural dentition  

IntroductionThe purpose of this study was to determine whether ultrashort echo time magnetic resonance imaging technology could be used to image teeth with orthodontic appliances in place. MethodsHigh-resolution 3-T ultrashort echo time magnetic resonance imaging was performed on 60 extracted premolars with fixed ceramic orthodontic appliances (Clarity, 3M Unitek, Monrovia, Calif; Radiance, American Orthodontics, Sheboygan, Wis; and Ice, Ormco, Glendora, Calif). The teeth were collected from the orthodontic clinic at the University of Alabama at Birmingham, and the institutional review board of the University of Alabama at Birmingham approved the study. Linear measurements of tooth morphology and orthodontic bracket dimensions were acquired with calipers and compared with virtual digital m...

314

Blue-Violet Light Emitting Diode (LED) Irradiation Immediately Controls Socket Bleeding Following Tooth Extraction; Clinical and Electron Microscopic Observations  

Abstract Objective: Bleeding control is a major concern during dental surgery. A novel photocoagulation method using an irradiating blue-violet light emitting diode (LED) was investigated. Background: Some dental light-curving units can emit blue-violet wavelengths around 380?515?nm with two peaks (410?nm and 470?nm). These wavelengths can cover the maximum absorption spectra of hemoglobin (430?nm). Materials and Methods: Blue-violet LED 380?515?nm, 750?mW/cm2, 10?sec (7.5?J/cm2) was used. Irradiation was performed for 10?sec or an additional 10?sec for 10 cases of tooth extraction at a distance of 1?cm from the socket. Bleeding was stopped by conventional roll pressure in another five cases as a control. Bleeding time for both procedures was measured. A Mann?Whitney U test was used for st...

315

The in vitro viability and growth of fibroblasts cultured in the presence of different bone grafting materials (nanobone and straumann bone Ceramic)  

In order for a dental implant to be restored optimally, it must be placed in an ideal anatomic position. However, this is not always possible, since physiological wound healing after tooth removal, often results in hard and soft tissue changes which ultimately compromises ideal implant placement. With the aim of minimising the need for tissue augmentation, several alveolar ridge preservation (ARP) techniques have been developed. These often require the use of grafting material and therefore increase the risk of disease transmission. Leukocyte and platelet-rich fibrin (L-PRF) is a newly developed platelet concentrate that is prepared from the patient's own blood. Clinical research has indicated that it improves wound healing and stimulates bone formation. We present a case where L-PRF was successfully used in an ARP procedure to facilitate implant placement in a compromised extraction socket. PMID:16783734

316

Flapless immediate implant placement with or without immediate loading: a histomorphometric study in beagle dog  

Blanco J, Linares A, Villaverde G, Perez J, Munoz F: Flapless immediate implant placement with or without immediate loading. a histomorphometric study in beagle dog. J Clin Periodontol 2010; 37: 937-942. doi: 10.1111/j.1600-051X.2010.01608.x. Abstract Objective: To assess the osseointegration process after flapless immediate implant placement with or without immediate loading. Material and Methods: This study was carried out on six beagle dogs. Four implants were placed in the lower jaw (two per side) in each dog immediately after tooth extraction (3rd and 4th premolars). Flapless immediate implant placement was performed in one hemimandible (control). The same procedure was carried out in the contra-lateral side and immediate prosthesis was connected with occlusal contacts (test). After 3...

317

Comprehensive dental implantology: the complete surgical approach with 30 month follow up  

Abstract Though dental implant placement is now a well accepted surgical procedure, practitioners of dental implantology will often be faced with more and more complex problems to overcome as patients' demands increase: there may be hard and soft tissue factors that will hinder the stabilisation of the peri implant mucogingival complex following such surgery. This is a step by step description of the comprehensive application of a number of surgical procedures illustrated by a case report with its 30 month follow up: The extraction and immediate insertion of a dental implant into the modified vacated tooth socket. The insertion of a dental implant into what is considered an infected apical area. The use of the mineral portion of bovine bone (Bio Oss, Geistlich, Wolhusen, Switzerland) to fi...

318

Resorption of monetite granules in alveolar bone defects in human patients  

Bone grafting is often required to restore mandibular or maxillary bone volume prior to prosthetic tooth root implantation. Preclinical animal models are often used to study the in vivo properties of new bone graft products designed for human use. Although animal studies may offer valuable data regarding bioperformance, materials do not necessarily perform the same in human patients. In this study we implanted bovine hydroxyapatite (BH), a widely used porous apatite granule, and dicalcium phosphate anhydrous (monetite) granules, bilaterally in human patients post extraction alveolar sockets. After six months, histomorphometrical analysis of the biopsies revealed that the amount of bone regenerated with monetite (59.5 +- 13%) was significantly higher than that obtained with BH (33.1% +- 4.9...

319

Povidone-iodine: an anti-oedematous agent?  

Polyvinylpyrrolidone-iodine (PVP-I) is a well-known antiseptic, widely used in various preparations and concentrations in all surgical fields. It is also used as an irrigant for open wounds and in some centres for irrigating sockets after tooth extraction. One of the authors (GA) incidentally discovered an anti-oedematous effect of PVP-I after using it in low concentration as an irrigant/coolant during the surgical removal of lower third molars. A prospective randomized clinical trial was subsequently performed on 50 patients (25 control, 25 treatment group) undergoing removal of impacted lower third molars. In the treatment group a 0.5% PVP-I solution at a concentration of 0.5 mg/ml (we call it as "Arakeri's iodine solution") resulted in a significant reduction in postoperative swelling c...

320

Interventions for replacing missing teeth: dental implants in fresh extraction sockets (immediate, immediate-delayed and delayed implants)  

Abstract Background: -Immediate- implants are placed in dental sockets just after tooth extraction. -Immediate-delayed- implants are those implants inserted after weeks up to about a couple of months to allow for soft tissue healing. -Delayed- implants are those placed thereafter in partially or completely healed bone. The potential advantages of immediate implants are that treatment time can be shortened and that bone volumes might be partially maintained thus possibly providing good aesthetic results. The potential disadvantages are an increased risk of infection and failures. After implant placement in postextractive sites, gaps can be present between the implant and the bony walls. It is possible to fill these gaps and to augment bone simultaneously to implant placement. There are many...

 
 
 
 
321

The socket-shield technique: a proof-of-principle report  

Hurzeler MB, Zuhr O, Schupbach P, Rebele SF, Emmanouilidis N, Fickl S. The socket-shield technique: a proof-of-principle report. J Clin Periodontol 2010; 37: 855-862. doi: 10.1111/j.1600-051X.2010.01595.x. Abstract Aim: Clinical studies have suggested that retaining roots of hopeless teeth may avoid tissue alterations after tooth extraction. Therefore, the objective of this proof-of-principle experiment was to histologically assess a partial root retention (socket-shield technique) in combination with immediate implant placement. Material and Methods: In one beagle dog, the third and fourth mandibular pre-molar were hemisected and the buccal fragment of the distal root was retained approximately 1 mm coronal to the buccal bone plate. Following application of enamel matrix derivate, a titan...

322

Stevens-Johnson syndrome: a case report  

Non-steroidal anti-inflammatory drugs are commonly prescribed in dental practice after minor oral surgical procedures such as tooth extraction. Diclofenac sodium is one of the non-steroidal anti-inflammatory drugs widely used for pain relief in dentistry. Although adverse reactions to these drugs are rare, at times they can cause a life-threatening phenomenon. Stevens-Johnson syndrome is one such potentially lethal adverse drug reaction. Most reported cases of analgesic-induced Stevens-Johnson syndrome were due to oxicams or propionic acid derivatives. There are very few detailed reports of Stevens-Johnson syndrome due to use of diclofenac. We report here a case of Stevens-Johnson syndrome which occurred due to use of diclofenac sodium. The clinical features of this condition and multidisciplinary management of the patient are described in brief. (J Oral Sci 52, 343-346, 2010)   

323

Origin of celiac disease: How old are predisposing haplotypes?  

We recently presented the case of a first century AD young woman, found in the archaeological site of Cosa, showing clinical signs of malnutrition, such as short height, osteoporosis, dental enamel hypoplasia and cribra orbitalia, indirect sign of anemia, all strongly suggestive for celiac disease (CD). However, whether these findings were actually associated to CD was not shown based on genetic parameters. To investigate her human leukocyte antigen (HLA) class II polymorphism, we extracted DNA from a bone sample and a tooth and genotyped HLA using three HLA-tagging single nucleotide polymorphisms for DQ8, DQ2.2 and DQ2.5, specifically associated to CD. She displayed HLA DQ 2.5, the haplotype associated to the highest risk of CD. This is the first report showing the presence of a HLA haplotype compatible for CD in archaeological specimens. PMID:23066327

324

Improved Sensitivity of Optical Frequency Domain Reflectometry-Optical Coherence Tomography Using a Semiconductor Optical Amplifier  

We demonstrate an approach to enhance the optical frequency domain reflectometry (OFDR)-optical coherence tomography (OCT) sensitivity using a semiconductor optical amplifier (SOA) and a superstructure grating-distributed Bragg reflector (SSG-DBR) laser. We find that the sensitivity of the OCT images of an extracted canine tooth increases as a function of SOA injection current due to amplification through stimulated emission. At the injection current of 150 mA, the sensitivity of the OCT image is increased to a factor of 22.8 dB when compared to the unamplified OCT. Furthermore, an 18 ?m axial resolution of the OCT in dental tissue is achieved using the discrete wavelength-swept SSG-DBR laser with an axial scan rate of 0.25 kHz. The observed results suggest that the optical amplification by SOA can significantly enhance the sensitivity of the OFDR-OCT system with a high-resolution.   

325

A comparison of strains generated during placement of five endodontic posts.  

Twenty-five extracted human maxillary central incisors were randomly divided into five equal groups. Crowns were removed 1 mm incisal to the cementoenamel junction. Endodontic treatment was carried out and each tooth was affixed with two strain gauges. The strain gauge wires were connected to a Wheatstone Bridge circuit. Each group of five teeth was restored with either a Para-Post Plus (the control post), Flexi-Post, Vlock post, Kurer Fin Lock Anchor, or a Radix Anchor. Strains generated during post placement were recorded and compared for the five groups using a one-way analysis of variance. The maximum strains accompanying placement of the Kurer Fin Lock Anchor and the Radix Anchor were significantly higher than those induced by placement of the other posts. Also, when the threaded posts were allowed to contact the bottom of the prepared channel, high strains resulted. PMID:1811040

326

Comparison of the retention of endodontic posts after preparation with EDTA.  

Significant differences in the retention of preformed endodontic posts for endodontically treated teeth were determined with (1) parallel-sided, passively placed Para-Post dowel versus mechanically engaging, threaded Flexi-Post dowel; (2) irrigation of canals with EDTA; (3) cementation with urethane dimethacrylate resinous or zinc phosphate cement. It was hypothesized that EDTA would substantially increase retention by removing the smear layer on the prepared canal wall and create micromechanical retention in the dentin. Extracted teeth were prepared with endodontic posts and divided in groups representing combinations of variables. The forces for post removal and the locations of the retentive bond failures were recorded. The results indicated that EDTA did not significantly affect retention. The Flexi-Post dowel was significantly more retentive than the Para-Post dowel but also exhibited a greater potential for tooth damage compared with the Para-Post dowel during retentive failure loads. PMID:8445555

327

Effect of Chlorhexidine Gluconate, Clearfil Protect Bond, and KTP Laser on Microleakage Under Metal Orthodontic Brackets with Thermocycling  

Abstract Objective: The purpose of this study was to evaluate the effects of antimicrobial pretreatments [chlorhexidine gluconate (CHX), Clearfil Protect Bond (CPB), and potassium-titanyl-phosphate (KTP) laser] on microleakage under metal orthodontic brackets. Materials and Methods: Sixty freshly-extracted human premolars were randomly assigned to four equal groups: group 1, 37% phosphoric acid; group 2, 37% phosphoric acid?+?2% CHX; group 3, 37% phosphoric acid?+?KTP laser; and group 4, CPB. The teeth were kept in distilled water for 24?h, and thereafter subjected to 500 thermal cycles. Then specimens were sealed with nail varnish, stained with 0.5% basic fuchsin for 24?h, sectioned, and evaluated under a stereomicroscope. Microleakage was scored with regard to the adhesive?tooth interfac...

328

Microleakage of ceramic inlays luted with different resin cements and dentin adhesives  

Statement of problem Despite recent advances in adhesive dentistry, resin cement/dentin adhesive combinations are not able to prevent microleakage in ceramic inlays. Marginal quality of tooth-colored restorations in large Class II cavities is satisfactory in enamel margins, but microleakage in dentin margins remains a concern. Purpose The purpose of this study was to evaluate the microleakage of all-ceramic inlays luted with 2 dual-polymerizing resin cements or 1 autopolymerizing resin cement in combination with different dentin adhesives. Material and methods One hundred and twenty extracted human mandibular third molars were used in this study. Teeth were prepared to receive Class II MOD inlays with enamel gingival margins on 1 proximal surface and dentin gingival margins on the other su...

329

Mesenchymal stem cells associated with porous chitosan-gelatin scaffold: A potential strategy for alveolar bone regeneration  

Abstract Tissue engineering has emerged as a novel treatment for replacement of lost bone tissue. This study evaluated the effects of a chitosan-gelatin scaffold seeded with bone marrow mesenchymal stem cells (BMMSCs) in the healing process of tooth sockets in rats. BMMSCs isolated from transgenic rats expressing enhanced green fluorescent protein (eGFP) were expanded and seeded on a chitosan-gelatin scaffold. These constructs were cultured for three days and characterized by scanning electronic microscopy (SEM) and energy dispersion spectroscopy (EDS). Receptor rats received the implant in the left sockets, after upper first-molar extraction. Right alveoli served as control. Animals were sacrificed at days 5, 21, and 35 post-graft for examination. Morphometry demonstrated increased bone m...

330

Postextraction Implant Placement with Immediate Provisionalisation and Finalisation, Using a Simplified Technique: Technical Notes and a Case Report  

Trauma of maxillary teeth is a common accident. In most cases, the result is a root or crown fracture requiring tooth extraction and implant placement. Immediate postextraction implants are considered an effective option for restoring missing teeth in order to achieve successful aesthetic and functional outcomes. The aim of this article is to describe a clinical case in which a fractured maxillary canine was replaced by an osseointegrated implant using a simplified technique in a patient who was a smoker and presented poor oral hygiene. The technique adopted permits a reduction of the number of implant components and consequently a lower cost of treatment, while at the same time maintaining acceptable aesthetic and functional outcomes.

331

Influence of tubule orientation on cone-shaped texture development in laser-ablated dentin.  

In the present paper, the influence of tubule orientation on surface texture development was studied. Specimens of dentin with a wide range of tubule orientations were extracted from caries-free human teeth, processed using KrF laser radiation, and analyzed by scanning electron microscopy. When a transverse cross section of dentin cut perpendicularly to the tooth axis is processed with KrF laser radiation, a cone-like topography develops in the inner dentin where tubules are parallel to the laser beam. When laser processing is carried out in the outer dentin, because tubules are significantly tilted with respect to the laser beam, flat surfaces are achieved. The surface texture after laser processing depends effectively on the angle between the tubules and the laser beam. The dependency of cone growth on tubule orientation was confirmed using a simple differential ablation model. PMID:16897108

332

The effect of calcium phosphate bone substitute on defect resolution around a rough-surfaced dental implants in dogs  

Abstract Gap defects often exist around dental implants due to morphological differences between the natural tooth extraction socket and the dental implant. Techniques that can resolve such gap defects include implant surface modification and filling of the defects with bone substitutes. Modified surfaces are generally more effective in this regard than smooth surfaces. Favorable results have also been reported using bone substitutes. This study evaluated the effectiveness of a calcium phosphate (CaP) bone substitute for resolving gap defects around implant surfaces that have been treated with grit blasting and thermal etching. Implants were placed in edentulous areas in four mongrel dogs. Gap defects with a diameter of 2 mm were prepared surgically around the dental implants. These defect...

333

Thoracic complications of deeply situated serous neck infections  

Background. Ludwig's angina is a rapidly spreading cellulitis that may produce upper airway obstruction often leading to death. There is very little published information regarding this condition in the pregnant patient. Case. A 24-year old black female was admitted at 26 weeks gestation with tooth pain, submandibular swelling, severe trismus, and dysphagea, consistent with Ludwig's angina. Her treatment included emergent tracheostomy, incision and drainage of associated spaces, teeth extraction, and antibiotic therapy. Conclusions. During a life threatening infectious situation such as the one described, risks of maternal and fetal morbidity include both septicemia and asphyxia. Furthermore, the healthcare provider must consider the risks that the condition and the possible treatments may cause the mother and her unborn child. PMID:8450077

334

Adrenaline toxicity following accidental administration of the 1:1000 solution during dental procedures: Four case reports.  

Four patients aged between 35 and 50 years attended the out patients department of a dental hospital for tooth extraction. Following administration of, what was thought to be the local anesthetic, Lignocaine, to the gum and sub mucosa, they all collapsed. What had, in fact, been injected was 1:1000 adrenaline. We would like to report the symptoms, signs and investigation findings that followed. Significantly elevated Troponin T, CPK (total), CPK (MB) and ECG changes were seen. Electromyography and Nerve Conduction Studies showed a myopathic pattern and reduction in motor and sensory conduction respectively. These patients were followed up for a period of five years. Long term effects such as tremor, muscle weakness, easy fatigability and shortness of breath on exertion, which is not reported in the literature, were reported by all patients. PMID:22687774

335

Dexrazoxane shows cytoprotective effects in zoledronic acid-treated human cells in vitro and in the rabbit tibia model in vivo  

Introduction: Bisphosphonates are important and effective drugs in oncology and osteoporosis therapy. They accumulate in the bone matrix becoming released and active by bone resorption. This leads to effective inhibition of tumor cells and bone degradation. A side effect of bisphosphonates similar to other drugs like denosumab is osteonecrosis of the jaws (ONJ). This problem mostly occurs after tooth extraction. We studied the cytoprotectant dexrazoxane known from anthracycline chemotherapy for cytoprotection in nitrogen-containing bisphosphonate treated cells and in the rabbit tibia model to evaluate a possible value in ONJ management. Materials & methods: Human osteoblasts (HOB) P2 cells and Human ginigiva fibroblasts (HGF) P2 cells were treated with zoledronic acid (50@mmol/L) and the c...

336

Histopathological characteristics of primary teeth in pre-term very low birth-weight child: Case report  

Several studies have reported that the prevalence of enamel hypoplasia in pre-term low birth-weight children is higher than that in normal birth-weight children. However, the features of primary teeth dentin in pre-term low birth-weight children are rarely reported. We clinically examined a pre-term very low birth-weight child, and performed histopathological examinations of the extracted primary incisors. Hypomineralized enamel was observed in the permanent upper central incisors, while enamel defects were not detected in primary teeth. In the histopathological examinations, several features of dentin defects, such as irregular dentinal tubules and globular dentin, were observed on the pulpal side of dentin. These findings indicated that dentin formation in the present low birth-weight children was mainly affected during the natal and postnatal periods. Our results provide the evidence that tooth formation in low birth-weight children is affected by postnatal systemic derangement.   

337

Lymphomatoid Granulomatosis Presenting with Gingival Involvement in an Immune Competent Elderly Male  

Lymphomatoid granulomatosis (LYG) represents a B cell lymphoproliferative disorder that appears to be driven by infection of the lesional cells by Epsteinâ??Barr virus (EBV). Although not a common condition, the overwhelming majority of cases affect the lungs and mediastinal lymph nodes. Oral mucosal involvement has been documented in only one other report. We describe an 82-year-old man who developed a chronic oral ulcer following extraction of a mandibular molar tooth. Biopsy of the ulcer identified large atypical mononuclear cells that had a B cell immunophenotype and were associated with the walls of several arterioles in the sample. In situ probes for EBV-encoded small RNA showed prominent labeling of these large cells, suggesting the possibility of LYG. Imaging studies identified med...

338

Iatrogenic mandibular fracture associated with third molar removal: Can it be prevented?  

Abstract in english Removal of third molars is the most common procedure in oral surgery. It may be associated with complications, such as sensory damage , dry socket, infection and iatrogenic damage. A case of mandibular angle fracture during third molar extraction in a 37-year-old female is reported. Literature review on the possible etiologies and ways of prevention were recorded. The reason is believed to be multifactorial and include: age, gender, degree of impaction, relative volume of (more) the tooth in the jaw, preexisting infection or bone lesions, failure to maintain a soft diet in the early postoperative period and the surgical technique. It is possible to reduce the risk of this complication by adoption of preventive measures.

339

Periapical tissue reactions to calcium hydroxide and MTA after external root resorption as a sequela of delayed tooth replantation  

Abstract--- Clinical experience has shown that most avulsed teeth are replanted after a long extra-alveolar time and dry or inadequate wet storage, causing necrosis of periodontal ligament cells. This condition invariably leads to development of external root resorption, leaving the filling material in contact with the periapical connective tissues. In this study, the periapical tissue reactions to calcium hydroxide (CH) and mineral trioxide aggregate (MTA) were evaluated after occurrence of external root resorption as an expected sequela of delayed tooth replantation. Twenty male Wistar rats (Rattus norvegicus, albinus) had their right upper incisor extracted and maintained in dry storage for 60-min. Then, the dental papilla, enamel organ, pulp tissue, and periodontal ligament were remove...

340

Temporal abscess after third molar extraction in the mandible  

Background Dental infections resulting before or after third molar removal are complications in which the maxillofacial surgeon may have to initiate an earlier management. The severe dental infections resulting before or after this procedure is one of the few life-threatening complications in which the maxillofacial surgeon may have to initiate an earlier management. Infections involving the temporal space are rare and infrequently reported. Infections in this space have also been observed secondary to maxillary sinusitis, maxillary sinus fracture, temporomandibular arthroscopy, and drug injection, although more commonly associated to third molar infections. Case report A 22-year-old man had undergone extraction of tooth 38 secondary to pericoronaritis by a general dentist. Physical examin...

 
 
 
 
341

Influence of the parameters of the Er:YAG laser on the apical sealing of apicectomized teeth  

Failures in the sealing of the tooth apex have been considered to be responsible for most of the failures of apical surgeries. The Er:YAG laser has been proposed as an alternative for the use of rotator instruments in surgical endodontics due to its precision, lack of vibration, less post-operative discomfort, bacterial reduction, and less stress for patients and professionals. Following approval by the ethics committee, 12 extracted human canines without previous endodontic treatment with anatomically normal roots and free from apical lesions were washed in running tap water and disinfected. The teeth were sectioned axially at the crown-root junction and submitted to routine endodontic treatment. The apical limit was set at 1 mm before the apical foramen. The root canals were routinely f...

342

Bond strength of Resilon/Epiphany compared with Gutta-percha and sealers Sealer 26 and Endo Fill  

Abstract This study evaluated the bond strength of Epiphany/Resilon to radicular dentine and compared this with that of Gutta-percha sealed with Sealer 26 and also Endo Fill. Fifteen human single-rooted extracted teeth had their root canals enlarged to a standardised internal root diameter of 1.5-mm. The teeth were filled with: Group I - Epiphany/Resilon cones, Group II - Sealer 26/Gutta-percha cones and Group III - Endo Fill/Gutta-percha cones. Three 2-mm-thick cross-sections were obtained from each tooth (n-=-15) and subjected to a push-out test (1-mm-min-1). The means (MPa) were compared using anova /Newman-Keuls tests. There were no statistically significant differences between Group I and Group II (P->-0.01). Both bond strengths were significantly higher than that of Group III (P-/Res...

343

[The properties of dentin and resinified dentin in the tensile test].  

The purpose of this study is to evaluate the effect of resinifying therapy to the hard tissue of tooth by using measurement of the tensile strength. The fresh extracted maxillary anterior teeth having been cleaned and sterilized were divided into two groups. The control group was placed into 9% N-saline solution of 37 +/- 1 degrees C. The experimental group was treated with resinifying therapy. The tensile specimens were shaped by turning in a lathe until it satisfied the tensile test requirement of Mechanics of Materials except that they were hollow. A set of special split jig was made for this test. Instron Universal Testing Machine was used for measuring the load on the specimens. The loading speed was 0.05 mm/min. The straining meter was used to measure the tensile strain. The result revealed that tensile strength of resinifying dentin was little lower than that of unresinified dentin. The resinified dentin didn't increases stiffness or brittleness. PMID:2517091

344

Wear and morphology of infiltrated white spot lesions  

Objectives.To evaluate the toothbrush wear resistance of infiltrated artificial white spot lesions following two infiltration strategies, and to assess their ultramorphology.Methods.Flat enamel surfaces from freshly extracted bovine teeth were polished and immersed in a Buskes demineralising solution for 30 days to create incipient caries-like lesions (white spots). Two experimental regions on the surface of each tooth were infiltrated with an infiltrant and a commercial etch-and-rinse adhesive. Toothbrush abrasion was applied for 20,000 cycles. Vertical wear loss of the infiltrated areas was measured after 10,000 and 20,000 cycles against unabraded and abraded enamel using confocal laser scanning microscopy (CLSM; multiple t-tests, alpha = 0.05). Each lesion's surface and cross-section we...

345

Penetration pattern of rhodamine dyes into enamel and dentin: confocal laser microscopy observation  

Synopsis Enamel and dentin are susceptible to extrinsic and intrinsic stains. The purposes of this study were to determine the penetration pattern of Rhodamine B and dextran-conjugated Rhodamine B into the enamel and dentin as observed by confocal laser microscopy and to relate it to the penetration pattern of hydrogen peroxide commonly used as an active ingredient in tooth-whitening agents and high-molecular-weight staining molecules. Eighteen recently extracted human maxillary anterior teeth were used. Teeth were cleaned and painted with nail varnish except for the crown area above the cemento-enamel junction (CEJ). The painted teeth were then immersed in Rhodamine B and dextran-conjugated Rhodamine B (70-000-MW) for 4, 7, 10 and 15-days. Teeth were sliced to 3-mm thickness in transverse...

346

Evaluation of lidocaine and mepivacaine for inferior third molar surgery  

Abstract in english Objective: The aim of this study was to compare 2% lidocaine and 2% mepivacaine with 1:100,000 epinephrine for postoperative pain control. Study design: A group of 35 patients, both genders were recruited, whose had ages ranged from 13 to 27 years-old and had two inferior third molars in similar positions to be extracted. The cartridges were distributed to the patients according to a randomised pattern, where lidocaine was in the control group and mepivacaine in the exper (more) imental group. Results: Results showed no significant association between the anesthetics and postoperative pain, pulp sensibility after one hour, gender, tooth position and duration of the surgical procedure. Conclusions: It was shown that lidocaine and mepivacaine have similar time of anesthesia, they are adequate for surgical procedures that last one hour, and there was no difference between the two anesthetics in relation to the severety of post-operative pain.

347

Peripheral nerve may regulate the jaw bone resorption after tooth extraction  

SummaryA various amount of alveolar ridge resorption is likely to occur after tooth extraction, making it difficult to restore the missing teeth with either endosseous dental implants or prosthodontics approaches. It is commonly thought that the bone resorption is due to the absence of the mechanical stimulation from the occlusal force. However, regulation of the bone mass is a complex homeostatic system involved in hormonal, paracrine/autocrine, mechanical and neuronal nature. Studies have shown that the central and peripheral nervous system play an important role in bone remodeling. The hypothalamus integrates peripheral and central signals, and sends efferent hormonal and neuronal signals in response to stimulation. Numerous neuropeptides detected in the bone marrow have effect on the o...

348

Influence of deep dry cryogenic treatment on cutting efficiency and wear resistance of nickel-titanium rotary endodontic instruments.  

This study tested the effect of cryogenic treatment on nickel-titanium (NiTi) endodontic instruments. Ten rotary NiTi instruments (ProFile 30, 0.06; Dentsply Maillefer Instruments SA, Baillegues, Switzerland)) were subjected to deep dry cryogenic treatment at liquid nitrogen temperature (-185 degrees C) (group A) and compared with that of nontreated instruments (group B). Root canals of 30 extracted permanent mandibular premolars were prepared to size 25 using ProFile 0.04 taper rotary NiTi instruments. Each instrument was used in 4 root canals for a total of 240 seconds. Cutting efficiency in rotary motion was assessed from weight loss of tooth samples after instrumentation. Wear resistance was assessed from surface defects on cutting heads pre- and postinstrumentation using scanning electron microscope. The weight loss was significantly higher in group A (p cryogenic treatment increases the cutting efficiency significantly but not the wear resistance. PMID:17963963

349

Deproteinized bovine bone mineral in marginal defects at implants installed immediately into extraction sockets: an experimental study in dogs  

Abstract Aim: To evaluate the influence of deproteinized bovine bone mineral (DBBM) particles concomitant with the placement of a collagen membrane on alveolar ridge preservation and on osseointegration of implants placed into alveolar sockets immediately after tooth extraction. Material and methods: The pulp tissue of the mesial roots of 3P3 was removed in six Labrador dogs and the root canals were filled. Flaps were elevated in the right side of the mandible, and the buccal and lingual alveolar bony plates were exposed. The third premolar was hemi-sectioned and the distal root was removed. A recipient site was prepared and an implant was placed lingually. After implant installation, defects of about 0.6-mm wide and 3.1-mm depth resulted at the buccal aspects of the implant, both at the t...

350

Osteomyelitis of the mandible in a group of 33 pediatric patients with congenital insensitivity to pain with anhidrosis  

Objective.To determine the frequency of mandibular osteomyelitis (OM) in patients with congenital insensitivity to pain with anhidrosis (CIPA) and to relate its appearance to possible risk factors.Methods. The records of 33 patients were reviewed for data concerning events of jaw OM, oral trauma, maxillofacial interventions, or OM of long bones. Results. Eighteen percent of the patients had mandibular OM. Of the six patients, preceding oral laceration was documented in one and tooth extraction in two. Seventy percent of the patients had OM of the limbs, but only 15% overlapped, having both jaw and limb OM. Half of the patients with mandibular OM had also OM of the limbs during the following year. There seems to be a correlation between high frequency of limb OM (at least 5 events per patie...

351

Comparison of self- and conventional-ligating brackets in the alignment stage  

This prospective study investigated the difference in clinical efficiency between Damon 3 self-ligating brackets (SLB) compared with Mini Diamond conventional ligating brackets (CLBs) during tooth alignment in straightwire fixed appliance therapy. Twenty-nine patients (10 males and 19 females), aged between 14 and 30 years, were randomly divided into two groups: 14 patients received the SLB and 15 received the CLB. Upper arch impressions were taken for pre-treatment records (T0). A transpalatal arch was soldered to both maxillary first molar bands prior to extraction of the maxillary first premolars, followed by straightwire fixed appliances (0.022 x 0.028 inch). A 0.014 inch nickel titanium (NiTi) wire was used as the levelling and aligning archwire. Four monthly reviews were undertaken a...

352

Cavernous Sinus Thrombophlebitis Related to Dental Infection  

Two cases of cavernous sinus thrombophlebitis (CST) caused by dental infection are described. A 64-year-old woman presented with palsies of the left oculomotor and trochlear nerves after tooth extraction for dental caries in the left maxilla. A 54-year-old man presented with palsy of the left trochlear nerve, sensory disturbance in the ophthalmic and maxillary divisions of the left trigeminal nerve, ptosis, proptosis, and chemosis after dental treatment for caries and periodontitis in the left maxilla. In both patients, computed tomography and magnetic resonance imaging with contrast medium showed non-enhanced lesions within the left cavernous sinus and dilation of the superior ophthalmic veins, which indicated CST. These conditions were resolved by administration of broad-spectrum antibiotics. CST is rare but lethal, so prompt diagnosis is crucial, and immediate appropriate treatment is essential.   

353

Orthodontic correction of a transposed maxillary canine and first premolar in the permanent dentition.  

The patient was a 16-year-old Japanese girl whose chief complaints were crowding and transposition of the maxillary canine and first premolar. A setup model was used to preoperatively align the teeth in their transposed positions. The amount of postoperative reshaping was estimated for the occlusal surfaces of the teeth. However, the patient did not wish to have her teeth reduced by reshaping or to have composite materials for restorative camouflage. Because she strongly expected alignment of her teeth in the correct intra-arch position, her transposed teeth were corrected without extraction of the transposed teeth. Cone-beam computed tomography was used to obtain more detailed information about the transposition, and the direction of tooth movement was examined. Although the duration of the treatment was long, both the crowns and the roots of the transposed teeth were aligned correctly. PMID:22999676

354

Ethnomedicinal investigation in Nandurbar district of Maharasthtra.  

The aborigines exploit medicinal virtues of tubers, roots fruits, seeds, flowers, leaves etc. from the forest and use in a variety of ways. The are used in the form of juice, decoction, oil, paste, extract, infusion and powder. Fresh parts are also used and the substances like sugar, sugarcandy, groundnut oil, milk and cow-ghee are used as additives. The native uses of medicinal plants are employed to better stomachcomplaints, rheumatic pains, spermatorrhoea, tooth-ache, head-ache, ear-ache, weakness, urinal troubles, fresh cuts, tumors, fever, mouth ulcer, bone fracture and few other human diseases. Total 47 species are being reported for the aforesaid ailments of these, applications of 32 species are unknown or little known. These are, however, desired for further scientific assessments for obvious reasons. PMID:22557270

355

Effects of self-ligating brackets on the surfaces of stainless steel wires following clinical use: AFM investigation  

Summary In orthodontic treatment, the frictional force between the archwire and bracket reduces the effectiveness of orthodontic treatment. The frictional force is affected not only by the geometry of the self-ligating brackets but also by physical changes between the bracket slots and archwire surfaces during sliding movement. This study examined quantitatively the effect of self-ligating treatments on the surfaces of stainless steel (SS) archwires during tooth movement in vivo by atomic force microscopy. Orthodontic 0.019---0.025- SS archwires after clinical use with the first bicuspid-extraction treatment were employed using the Damon 3MX SS self-ligating brackets, Clippy-C ceramic self-ligating brackets, and Kosaka SS brackets. Intact SS archwires were used as the control group. All SS...

356

Evaluation of Antimicrobial Efficacy of Herbal Alternatives (Triphala and Green Tea Polyphenols), MTAD, and 5% Sodium Hypochlorite against Enterococcus faecalis Biofilm Formed on Tooth Substrate: An In Vitro Study  

Introduction The purpose of this study was to evaluate the antimicrobial efficacy of Triphala, green tea polyphenols (GTP), MTAD, and 5% sodium hypochlorite against E. faecalis biofilm formed on tooth substrate. Methods Extracted human teeth were biomechanically prepared, vertically sectioned, placed in the tissue culture wells exposing the root canal surface to E. faecalis to form a biofilm. At the end of the 3rd and 6th weeks all groups were treated for 10 minutes with the test solutions and control and were analyzed qualitatively and quantitatively. Results Qualitative assay with 3-week biofilm showed complete inhibition of bacterial growth with Triphala, MTAD and NaOCl, except GTP and saline, which showed presence of bacterial growth. In quantitative analysis, GTP- and saline-treated t...

357

SPLINTED ZIRCONIA FIXED PARTIAL DENTURE SUPPORTED BY MINI IMPLANTS IN THE POSTERIOR MANDIBLE: A CASE REPORT.  

Abstract One of the most frequently extracted tooth is the mandibular molar. A highly accepted and elegant solution is to replace the missing molar with an endossous implant and a fixed crown. A biologically, anatomically and physiologically appropriate solution could be to replace the two roots of the missing molar with two implants. One way to incorporate the use of two implants to support a molar sized crown is to use implants of smaller diameter. Mini implants may successfully support fixed partial dentures in the posterior mandible in highly selected patients with an appropriate prosthetic design and occlusal scheme. Jaw forces, bone quality and volume are edentulous site conditions that may affect treatment decisions. The implant dentist should consider many diverse implant and prosthetic designs to appropriately treat the atrophic mandible. Zirconia splinted crowns supported by mini dental implants may be an effective treatment for selected posterior sites. PMID:23088425

358

Alkaline denaturation of dentin. A simple way to isolate human tooth enamel for electron spin resonance dosimetry  

Electron spin resonance (ESR) of tooth enamel is a recently developed method for the retrospective dose estimation of human radiation exposures. The assay requires isolation of enamel from dentin, which is difficult because the boundary between enamel and dentin is not easily discernible. Here we describe a simple method for isolating enamel by alkaline denaturation of dentin. The method requires 4 weeks, but scratching of the denatured and hence softened dentin is needed only once a week. Above all, no special skill is required. We found that the alkaline treatment did not cause deterioration of the ESR signal recorded in enamel exposed to 2 Gy of {gamma}-rays prior to its isolation. The assay is particularly suited for teeth containing many cracks that were generated during long-term storage after extraction of the teeth. Such teeth tend to disintegrate during enamel isolation processes, which poses difficulties to isolate enamel mechanically from individual small pieces. (author)

359

A Study on Dentigerous Cystic Changes with Radiographically Normal Impacted Mandibular Third Molars  

Background Dentigerous cyst develops in the follicular tissue surrounding the impacted lower third molar. A study was carried out to know the incidence of Association of Dentigerous cyst with radiographically normal impacted lower third molars and to draw the attention of the Oral Surgeons towards the prophylactic removal of impacted third molars. Methods A prospective study was done on 30 patients with impacted lower third molars which were indicated for extraction. The follicle tissue surrounding the impacted tooth was subjected for histopathologic investigations. Only those teeth with a radiographic finding of pericoronal space of less than 2.5 mm were considered. Two Oral Pathologists reviewed the slides for any changes suggestive of cystic pathology. Results Pathologic changes suggest...

360

A 5-year retrospective study of survival of zirconia single crowns fitted in a private clinical setting  

Objectives: The aim of this report was to evaluate the 5-year clinical performance and survival of zirconia (NobelProcera(TM)) single crowns. Methods: All patients treated with porcelain-veneered zirconia single crowns in a private practice during the period October 2004 to November 2005 were included. The records were scrutinized for clinical data. Information was available for 162 patients and 205 crowns. Results: Most crowns (78%) were placed on premolars and molars. Out of the 143 crowns that were followed for 5 years, 126 (88%) did not have any complications. Of those with complications, the most common were: extraction of abutment tooth (7; 3%), loss of retention (15; 7%), need of endodontic treatment (9; 4%) and porcelain veneer fracture (6; 3%). No zirconia cores fractured. In tota...

 
 
 
 
361

Potentiometric stripping analysis of zinc and copper in human teeth and dental materials  

Potentiometric stripping analysis (PSA) with oxygen as the oxidant has been used to determine soluble zinc and copper levels in exfoliated human teeth (all of which required extraction for orthodontic reasons) and commercial dental materials. The soluble zinc and copper contents of teeth were slightly below the zinc and copper contents in whole teeth reported by other researchers, except in the case of tooth with removed amalgam filling. Soluble zinc and copper concentrations of the dental materials and metalceramic crowns were 0.50-6.30, and of 2.00-4.30mg/g, respectively. The results of this work suggest that PSA may be a good method for zinc and copper leaching studies during the investigation of dental prosthetic materials' biocompatibility. Corrosive action of acidic media as evidence...

362

Potentiometric stripping analysis of zinc and copper in human teeth and dental materials.  

Potentiometric stripping analysis (PSA) with oxygen as the oxidant has been used to determine soluble zinc and copper levels in exfoliated human teeth (all of which required extraction for orthodontic reasons) and commercial dental materials. The soluble zinc and copper contents of teeth were slightly below the zinc and copper contents in whole teeth reported by other researchers, except in the case of tooth with removed amalgam filling. Soluble zinc and copper concentrations of the dental materials and metal ceramic crowns were 0.50-6.30, and of 2.00-4.30 microg/g, respectively. The results of this work suggest that PSA may be a good method for zinc and copper leaching studies during the investigation of dental prosthetic materials' biocompatibility. Corrosive action of acidic media as evidenced by SEM micrographs caused the leaching of metal ions from teeth. PMID:18565421

363

A case-control study assessing oral-health-related quality of life after immediately loaded single implants in healed alveolar ridges or extraction sockets  

Abstract Introduction: Tooth loss reduces oral-health-related quality of life (OHRQoL) as assessed with the 14-item Oral Health Impact Profile questionnaire (OHIP-14). Objectives: This prospective multicenter case-control study sought to (i) establish OHRQoL in patients requiring a single implant in the anterior maxilla and to (ii) compare these changes following implant placement and immediate provisionalization in extraction sockets with healed alveolar ridges up to 1 year. Material and methods: Ninety-six patients were enrolled in the study with 102 single implants (OsseoSpeed- AstraTech) provisionalized immediately after placement in sockets or after placement in healed ridges. A final crown was cemented after 12 weeks. OHIP-14 was registered before surgery (baseline), after 1 (provisi...

364

Clinical and Dental Computed Tomographic Evaluation 1 Year After Coronectomy  

Purpose Coronectomy is performed when contact between the mandibular third molar apex and the inferior alveolar nerve is suspected. The efficacy of coronectomy compared with conventional tooth extraction has been recognized in recent years. However, few studies have reported the postoperative prognosis of roots remaining in the bone or surrounding tissue. Therefore, a clinical evaluation was performed with dental computed tomographic imaging of the coronectomy sites 1 year after the procedure. Patients and Methods This study investigated 101 patients (116 teeth) who underwent a coronectomy from March 2006 through December 2009. They were recalled 1 year later for a clinical evaluation and dental computed tomographic imaging of the coronectomy sites. The clinical evaluation was based on pal...

365

Marginal adaptation of cast partial crowns made of pure titanium and a gold alloy under influence of a manual burnishing technique.  

The aim of this study was to determine the marginal adaptation of partial crowns from pure titanium and a gold alloy after two different cementation techniques. Forty freshly extracted human molars were prepared and randomly divided in four groups. Two groups were restored with partial crowns using the gold alloy Degulor M*. In one group, the crowns were fixed on the tooth by using a zinc phosphate cement. In the other group the margins were additionally burnished by using a hand burnisher No. 660. In the other two groups, partial crowns from pure titanium were cemented in the same way. The marginal quality was determined by quantitative margin analysis in the SEM using a replica technique. Partial crowns from a gold alloy showed significantly (P burnishing in both material groups. PMID:11380778

366

Periodontal surgery in furcation-involved maxillary molars revisited--an introduction of guidelines for comprehensive treatment.  

Maxillary molars with interradicular loss of periodontal tissue have an increased risk of additional attachment loss with an impaired long-term prognosis. Since accurate clinical analysis of furcation involvement is not feasible due to limited access, morphological variations and measurement errors, additional diagnostics, e.g., with cone-beam computed tomography, may be required. Surgical treatment options have graduated from a less invasive approach, i.e., keeping as much periodontal attachment as possible, to a more invasive approach: (1) open flap debridement with/without gingivectomy or apically repositioned flap and/or tunnelling; (2) root separation; (3) amputation/trisection of a root (with/without root separation or tunnel preparation); (4) amputation/trisection of two roots; and (5) extraction of the entire tooth. Tunnelling is indicated when the degree of root separation allows for opening of the interradicular region. Alternatively, root separation is performed particularly in root-canal treated teeth with reduced coronal tooth substance requiring crown restorations. As soon as the attachment of one or two roots in maxillary molars is severely reduced, root removal is indicated and performed either as amputation or trisection including the corresponding part of the clinical crown. While the indication for regenerative measures in maxillary molars with furcation involvement is very limited, extraction and replacement with implants is restricted, particularly in sites requiring complex alveolar ridge augmentation and sinus elevation. A systematic approach for decision making in furcation-involved maxillary molars is described in this overview, including what constitutes accurate diagnosis and what indications there are for the different surgical periodontal treatment options. PMID:20571843

367

Contemporary Oral and Maxillofacial Surgery  

Background Understanding the molecular features of bone repair and osseointegration may aid in the development of therapeutics to improve implant outcomes. The purpose of this investigation is to determine the gene expression dynamics during alveolar bone repair and implant osseointegration. Methods An implant osseointegration preclinical animal model was used whereby maxillary defects were created at the time of oral implant placement, while a tooth extraction socket healing model was established on the contralateral side of each animal. The surrounding tissues in the zone of the healing defects were harvested during regeneration for temporal evaluation using histology, immunohistochemistry, laser capture microdissection, and quantitative reverse transcription–polymerase chain reaction for the identification of a panel of 17 putative genes associated with wound repair. Results In both models, three distinct expression patterns were displayed: 1) genes that are slowly increased during the healing process, such as bone morphogenetic protein 4, runt-related transcription factor 2, and osteocalcin; 2) genes that are upregulated at the early stage of healing and then downregulated at later stages, such as interleukin and chemokine (C-X-C motif) ligands 2 and 5; and 3) genes that are constitutively expressed over time, such as scleraxis. Although some similarities between osseointegration and tooth extraction socket were seen, distinct features developed and triggered a characteristic coordinated expression and orchestration of transcription factors, growth factors, extracellular matrix molecules, and chemokines. Conclusions Characterization of these events contributes to a better understanding of cooperative molecular dynamics in alveolar bone healing, and highlights potential pathways that could be further explored for the enhancement of osseous regenerative strategies. PMID:9446977

368

Two cases of symptomatic trigeminal neuralgia with intracranial tumor noticed by tooth extraction  

We report two cases of symptomatic trigeminal neuralgia with intracranial tumor noticed by tooth extraction, which were diagnosed immediately by MRI. Case 1 was a 21-year-old male who had right facial sharp pain after removal of a right wisdom tooth in the mandible. He was suspected to be suffering from symptomatic trigeminal neuralgia because of his young age, no trigger zone, and pain while asleep. MRI revealed that an epidermoid tumor was compressing the right trigeminal nerve at the root entry zone. Near total excision of the tumor was performed and the pain disappeared. Case 2 was an 85-year-old female who had undergone extraction of stumps of right premolar and molar teeth in the mandible because of a throbbing intermittent pain in the right mandible. She was referred to our hospital because the pain was not relieved even though the wound was cured. The pain nearly disappeared by the administration of Neurotropin®. However, she was suspected to be suffering from symptomatic trigeminal neuralgia because of the long duration of pain, no trigger zone, and severe right hypoacusis. MRI revealed that an acoustic nerve tumor was compressing the right trigeminal nerve at the root entry zone. She was not operated on because of her age and the hypoacusis was considered to be irreversible, and so the pain was controlled. It is not always easy to distinguish between typical and symptomatic trigeminal neuralgia by means of only clinical findings. Therefore, it is useful to ascertain the presence of an intracranial process by MRI in order to make an accurate diagnosis of patients with trigeminal neuralgia or atypical facial pain.   

369

Demineralization of hard tooth tissue adjacent to resin-modified glass-ionomers and composite resins: a quantitative systematic review  

The purpose of this systematic review was to quantitatively find out whether resin-modified glass-ionomers (RM-GIC), in comparison to fluoride-containing composite resin and composite resin without fluoride, are associated with a more effective reduction of demineralization in hard tooth tissues under caries challenge. Five databases were systematically searched on clinical trials up to 6 April 2009. Article inclusion criteria: titles/abstracts relevant in answering the review question, published in English, two-arm (prospective) longitudinal trial; Exclusion criteria: not all included subjects accounted for at the end of the trial; subjects of both groups not followed up the same way; no randomized, quasi-randomized controlled study design for in situ and clinical trials; contains no computable continuous data. Quality assessment of the accepted in situ and clinical trials was performed. Data were extracted in the form of datasets, containing numbers of evaluated samples and mean result with standard deviation for both groups. Fifteen articles were selected for review. Two lacked computable data and were excluded; nine laboratory trials, three randomized in situ trials and one randomized control trial were accepted. From these, 97 continuous datasets were extracted. The evidence suggests that RM-GIC is associated with a higher reduction of demineralization in adjacent hard tooth tissue than composite resin without fluoride. No difference was found when RM-GIC was compared with fluoride-containing composite resin. RM-GIC showed efficacy in reducing demineralization. However, the internal validity of the current evidence is limited and further high-quality trials are needed. (J Oral Sci 52, 347-357, 2010)   

370

A comparison of space closure rates between preactivated nickel-titanium and titanium-molybdenum alloy T-loops: a randomized controlled clinical trial.  

The purpose of this study was to conduct a prospective randomized controlled clinical trial to evaluate the rate of space closure and tooth angulation during maxillary canine retraction using preactivated T-loops made from titanium-molybdenum alloy (TMA) and nickel-titanium (NiTi). Twelve patients (six males and six females) aged between 13 and 20 years who had upper premolar extractions were included, and each acted as their own control, with a NiTi T-loop allocated to one quadrant and TMA to the other using a split mouth block randomization design. The loops were activated 3 mm at each visit to deliver a load of approximately 150 g to the upper canine teeth. Maxillary dental casts, taken at the first and each subsequent monthly visit, were used to evaluate changes in extraction space and canine angulation. All used T-loops were compared with unused loops in order to assess distortion. Mixed model statistical analysis was used to adjust for confounding variables. The mean rate of canine retraction using preactivated NiTi and TMA T-loops was 0.91 mm/month (±0.46) and 0.87 mm/month (±0.34), respectively. The canine tipping rates were 0.71 degrees/month (±2.34) for NiTi and 1.15 degrees/month (±2.86) for TMA. Both the rate of space closure and the tipping were not significantly different between the two wire types. The average percentage distortion of the TMA T-loop was 10 times greater than that of the NiTi loops when all other variables were matched. There was no difference in the rate of space closure or tooth angulation between preactivated TMA or NiTi T-loops when used to retract upper canines. The NiTi loops possessed a greater ability to retain and return to their original shapes following cyclical activation. PMID:21415288

371

Diffusion of HEMA through Human Carious and Non-Carious Dentin In Vitro.  

Purpose: The aim of this study was to evaluate the diffusion of 2-Hydroxyethyl methacrylate (HEMA) from resin cement through dentin both affected and unaffected by caries through high-performance liquid chromatography (HPLC) at two time intervals. Materials and Methods: Ten freshly extracted restoration-free, caries-free and ten extracted carious human third molar teeth were used in this study. Standardized box-shaped Class I inlay cavities (6 mm long, 3 mm wide, 2 mm deep) were prepared in all teeth with a high-speed handpiece mounted on a standard cavity machine. In teeth affected by caries, after preparation, the remaining carious lesions were removed, with their removal guided by a proprietary caries detector dye. The remaining dentin thickness (RDT) between the pulpal wall of the cavity and the roof of the pulp chamber was measured at multiple points for each tooth so that groups of 10 teeth each were prepared with RDT 1.2 ± 0.5 mm. Lithium disilicate-based ceramic inlays were manufactured to restore the prepared cavities. A polypropylene chamber was attached to the cementoenamel junction of each tooth to contain 1 ml distilled water. Then, ceramic inlays were cemented with chemically polymerized resin cement (Multilink Automix) according to the manufacturer's instructions. Water elutes were analyzed by HPLC at 4.32 minutes and 24 hours. HEMA diffusion amounts were analyzed using two-way ANOVA and Tukey HSD tests (p dentin did not influence the amount of HEMA diffused through the dentin to the pulp space. Conclusions: The highest amount of eluted HEMA concentration detected was not viewed as critical for pulp tissue since the diffused HEMA amounts were below the level of cytotoxicity, according to the literature. PMID:23107279

372

Contribution of the tooth bud mesenchyme to alveolar bone.  

This study highlights the dynamic nature of the mesenchymal cells during tooth development from the bud to the bell stage. Condensing mesenchymal cells, labelled on either side of the developing tooth bud, move toward the presumptive roots forming an arc of cells under the dental papilla. These labelled cells take part in formation of the dental follicle, which contributes to both the tooth and its surrounding periodontium, including the supporting alveolar bone. This study, thus, physically links development of the tooth with the tissue into which it develops. The results obtained clearly indicate that the tooth organ is an entity comprising dental and periodontal tissue. PMID:19165875

373

Replantation of an immature permanent central incisor following pre-eruptive traumatic avulsion  

Abstract - Tooth avulsion represents 0.5-16% of traumatic injuries. Avulsion of a pre-eruptive left permanent maxillary incisor in a 6-year-old boy is presented. The immature tooth was replanted after rinsing with saline following 10 min dry extra-oral time. This case report describes treatment and a 2-year follow-up of the tooth. During the follow-up period, continuation of root development, pulp revascularization, and irregular dentin formation were demonstrated. The tooth is vital, functional, and esthetic. To the best of our knowledge, no such case of replantation of a pre-eruptive tooth has been reported previously.

374

Exogenous fibroblast growth factor 8 rescues development of mouse diastemal vestigial tooth ex vivo.  

Regression of vestigial tooth buds results in the formation of the toothless diastema, a unique feature of the mouse dentition. Revitalization of the diastemal vestigial tooth bud provides an excellent model for studying tooth regeneration and replacement. It has been previously shown that suppression of fibroblast growth factor (FGF) signaling in the diastema results in vestigial tooth bud regression. In this study, we report that application of exogenous FGF8 to the mouse embryonic diastemal region rescues diastemal tooth development. However, this rescue of diastemal tooth development occurs only in an isolated diastemal regions and not in the mandibular quadrant, which includes the incisor and molar germs. FGF8 promotes cell proliferation and inhibits apoptosis in diastemal tooth epithelium, and revitalizes the tooth developmental program, as evidenced by the expression of genes critical for normal tooth development. Our results also support the idea that the adjacent tooth germs contribute to the suppression of diastemal vestigial tooth buds by means of multiple signals. PMID:21412937

375

Evaluation of scaffold materials for tooth tissue engineering  

Recently, the possibility of tooth tissue engineering has been reported. Although there are a number of available materials, information about scaffolds for tooth tissue engineering is still limited. To improve the manageability of tooth tissue engineering, the effect of scaffolds on in vivo tooth regeneration was evaluated. Collagen and fibrin were selected for this study based on the biocompatibility to dental papilla-derived cells and the results were compared with those of polyglycolic acid (PGA) fiber and b-tricalcium phosphate (b-TCP) porous block, which are commonly used for tooth, dentin and bone tissue engineering. Isolated porcine tooth germ-derived cells were seeded onto one of those scaffolds and transplanted to the back of nude mice. Tooth bud-like structures were observed mor...

376

Inhibitory Effect of Interferon-? on Experimental Tooth Movement in Mice  

The aim of this study was to investigate the effects of interferon (IFN)-? on experimental tooth movement in mice using a murine experimental tooth movement model. An Ni-Ti closed-coil spring was inserted between the upper-anterior alveolar bones and the upper-left first molars in mice. We evaluated the relationship between local Ifn-? mRNA levels and orthodontic tooth movement. In other experiments, IFN-? was injected adjacent to each first molar every other day during tooth movement. After 12 days, the amount of tooth movement was measured. Tartrate-resistant acid phosphatase (TRAP)-positive cells at the pressure side of each experimental tooth were counted as osteoclasts. Local Ifn-? mRNA expression increased with orthodontic tooth movement. The number of TRAP-positive cells increased o...

377

Morphological studies on the healing process of tooth extraction wounds in whole body irradiated rats  

The present studies were performed to investigate the healing process of the tooth extraction wound in whole body irradiated rats and to clarify the effect of irradiation on bone metabolism. One hundred and seven Wistar rats of about 100 g body weight were used and divided into 3 groups. Whole body irradiated rats were given single exposure with a dose of 8 Gy. The region of the left upper molars of local irradiated rats as controls, was exposed to 8 Gy. On the 7th day after irradiation, the left upper first molar of each rat was extracted. The rats were sacrificed at intervals of 1 to 14 days after extraction. Non-irradiated rats were sacrificed at the same intervals after extraction. The maxillary bone including the extraction wound was evaluated, histologically, histometrically and ultrastructurally. From the histological and histometrical findings, the difference of the healing process between non-irradiated rats and locally irradiated rats is not significant. In whole body irradiated rats, the healing process especially in the socket was disturbed. The osteoblastic new bone formation following production of granulation tissue was interfered with. Ultrastructurally, the cytoplasmic organellae were poorly developed in the osteoblast and osteoid formation was reduced in the socket. But periosteal new bone formation was the same as that of the locally irradiated rats. In whole body irradiated rats, the osteoclasts in the interradicular alveolar bone were decreased and have smaller nuclei, compared with non-irradiated and locally irradiated rats. Histometrically, the amount of bone loss was decreased in whole body irradiated rats. Ultrastructurally, the cyoplasmic organellae and ruffled border were poorly developed in the osteoclasts of whole body irradiated rats. The findings suggested that irradiation induced cytological changes not only in osteoblasts but in osteoclasts and these changes resulted in the delayed healing of extraction wound. (author) 106 refs.

378

Effect of Static Magnetic Fields on the Osseointegration of Immediately Placed Implants: A Randomized Controlled Clinical Trial.  

PURPOSE:: The aim of this study was to evaluate the effects of static magnetic fields (SMFs) on the implants immediately placed in fresh extraction sockets. MATERIALS AND METHODS:: Twenty patients who were in need of 20 fixed implant-supported single crowns in the anterior maxilla were included. After tooth extraction, screw-type implants were placed immediately into fresh extraction sockets and were randomly covered with either magnetic abutment (test group) or conventional healing abutment (control group). Radio frequency analysis (RFA) was conducted at implant placement and after 1, 2, and 3 months. Marginal bone level changes were recorded 1, 2, and 3 months postoperatively. RESULTS:: The RFA measurements showed a significant higher stability for implants in test group than that of control group after 1 month (P = 0.04). At month 2, less crestal bone loss was found in the test group (P = 0.03). However, at month 3, there was no significant difference between the groups for both parameters (P > 0.05). CONCLUSION:: SMFs caused more noticeable increase in implant stability and less bone loss during the initial weeks of healing. PMID:23114829

379

The early treatment of unusual sever ectopic eruption of the bilateral maxillary canines in a young Japanese girl: A case report  

The purpose of this report was to describe an unusual severe ectopic eruption of the bilateral maxillary canines in a young patient aged 7 years and 8 months and to discuss the effects of early intervention such as extraction of the predecessors and fenestration of the affected canines. The patient was referred to the author’s clinic for a consultation regarding bilateral ectopically erupting maxillary canines with an ectopic maxillary right first molar. After improvement of the first molar, the affected canines were fully erupted and aligned in occlusion 3 years and 7 months after the extraction of primary canines. Before treatment, the findings on the orthopantomogram were as follows, there was no direct cause, both canine tooth germs were situated in very high positions, and the cusp tips of both canines were not overlapped with the roots of the adjacent lateral incisors (Sector 1). The maxillary left canine impacted horizontally in a mesio-distal direction (axial angulation: 90 degrees) could be successfully guided to eruption by early intervention such as the extraction of predecessors and three fenestrations. Even in severe ectopic cases, therefore, it is considered that traction may be postponed until no effect of fenestration can be detected in cases of early discovery and intervention when the crown top is situated in Sector 1.   

380

Ridge preservation: does it actually work?  

Post-extraction the alveolus undergoes modelling which reduces height and width. This may present a problem for subsequent crown and bridge or implant therapy. Ridge preservation is the use of grafts and/or membranes to try to minimize the loss of the alveolar ridge. Extraction sockets have been filled with autogenous, allogenic and alloplastic materials. Membranes or soft tissue were used to contain the graft. More recently biodegradable sponges and materials coated in growth factors have been tested. Studies have primarily looked at either maintenance of vertical and horizontal dimensions or the healing of the socket and how much of the graft material is incorporated into the newly formed bone. Irrespective of method or materials, there seems to be some maintenance of the alveolus. Bone fill seems to occur in preserved extraction sockets, but in most cases with a high percentage of residual graft particles. In general, there is a lack of evidence to show that ridge preservation aids in correct 3-D implant placement, maintains hard and soft tissue volume over a prolonged period of time or for success and survival of implants placed into ridge preserved sockets. Still the most effective way to maintain ridge volume is to keep the natural tooth. PMID:22046736

 
 
 
 
381

Cleft lip and palate: recommendations for dental anesthetic procedure based on anatomic evidences.  

Patients with cleft lip and palate usually present dental anomalies of number, shape, structure and position in the cleft area and the general dentist is frequently asked to restore or extract those teeth. Considering that several anatomic variations are expected in teeth adjacent to cleft areas and that knowledge of these variations by general dentists is required for optimal treatment, the objectives of this paper are: 1) to describe changes in the innervation pattern of anterior teeth and soft tissue caused by the presence of a cleft, 2) to describe a local anesthetic procedure in unilateral and bilateral clefts, and 3) to provide recommendations to improve anesthetic procedures in patients with cleft lip and palate. The cases of 2 patients are presented: one with complete unilateral cleft lip and palate, and the other with complete bilateral cleft lip and palate. The patients underwent local anesthesia in the cleft area in order to extract teeth with poor bone support. The modified anesthetic procedure, respecting the altered course of nerves in the cleft maxilla and soft tissue alterations at the cleft site, was accomplished successfully and the tooth extraction was performed with no pain to the patients. General dentists should be aware of the anatomic variations in nerve courses in the cleft area to offer high quality treatment to patients with cleft lip and palate. PMID:22437689

382

Cleft lip and palate: recommendations for dental anesthetic procedure based on anatomic evidences  

Abstract in english Patients with cleft lip and palate usually present dental anomalies of number, shape, structure and position in the cleft area and the general dentist is frequently asked to restore or extract those teeth. Considering that several anatomic variations are expected in teeth adjacent to cleft areas and that knowledge of these variations by general dentists is required for optimal treatment, the objectives of this paper are: 1) to describe changes in the innervation pattern o (more) f anterior teeth and soft tissue caused by the presence of a cleft, 2) to describe a local anesthetic procedure in unilateral and bilateral clefts, and 3) to provide recommendations to improve anesthetic procedures in patients with cleft lip and palate. The cases of 2 patients are presented: one with complete unilateral cleft lip and palate, and the other with complete bilateral cleft lip and palate. The patients underwent local anesthesia in the cleft area in order to extract teeth with poor bone support. The modified anesthetic procedure, respecting the altered course of nerves in the cleft maxilla and soft tissue alterations at the cleft site, was accomplished successfully and the tooth extraction was performed with no pain to the patients. General dentists should be aware of the anatomic variations in nerve courses in the cleft area to offer high quality treatment to patients with cleft lip and palate.

383

Simultaneous augmentation of hard and soft tissues for implant site preparation using recombinant human platelet-derived growth factor: a human case report.  

This paper documents the treatment of a patient for whom a tissue engineering approach was used for both soft and hard tissue implant site development following the extraction of a failing maxillary left central incisor. The tooth had advanced pocketing and recurrent abscess formation secondary to failing endodontic treatment. Extraction revealed a lack of buccal plate as well as insufficient soft tissue for anterior esthetics. After extraction, the bony defect was filled with freeze-dried mineralized bone allograft mixed with recombinant human platelet-derived growth factor (rhPDGF), and a titanium-reinforced expanded polytetrafluoroethylene membrane was placed over it. The soft tissue deficiency was corrected with a pediculated connective tissue graft, and the graft bed was rinsed with rhPDGF. Seven months after surgery, the site was re-entered for implant placement. The grafted site was trephined for histologic analysis and an implant was placed. Subsequently, the implant osseointegrated and was restored. The radiographic and clinical results were acceptable. Histologic analysis revealed bone regeneration. Although this approach needs further investigation, this report emphasizes the potential for the use of rhPDGF for simultaneous soft and hard tissue implant site preparation. PMID:18351201

384

Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development.  

Classical tissue recombination studies demonstrated that initiation of tooth development depends on activation of odontogenic potential in the mesenchyme by signals from the presumptive dental epithelium. Although several members of the Wnt family of signaling molecules are expressed in the presumptive dental epithelium at the beginning of tooth initiation, whether Wnt signaling is directly involved in the activation of the odontogenic mesenchyme has not been characterized. In this report, we show that tissue-specific inactivation of beta-catenin, a central component of the canonical Wnt signaling pathway, in the developing tooth mesenchyme caused tooth developmental arrest at the bud stage in mice. We show that mesenchymal beta-catenin function is required for expression of Lef1 and Fgf3 in the developing tooth mesenchyme and for induction of primary enamel knot in the developing tooth epithelium. Expression of Msx1 and Pax9, two essential tooth mesenchyme transcription factors downstream of Bmp and Fgf signaling, respectively, were not altered in the absence of beta-catenin in the tooth mesenchyme. Moreover, we found that constitutive stabilization of beta-catenin in the developing palatal mesenchyme induced aberrant palatal epithelial invaginations that resembled early tooth buds both morphologically and in epithelial molecular marker expression, but without activating expression of Msx1 and Pax9 in the mesenchyme. Together, these results indicate that activation of the mesenchymal odontogenic program during early tooth development requires concerted actions of Bmp, Fgf and Wnt signaling from the presumptive dental epithelium to the mesenchyme. PMID:19631205

385

[The inaccuracy of the panoramic radiograph as a tool to determine tooth inclination].  

The panoramic radiograph is one of the most common radiographs in orthodontics. It is sometimes used as an aid for the decision which teeth should be extracted as part of the individual treatment plan. When treating patients with clear plates (for example, Invisalign), it is very important to know the inclination direction of the involved teeth. Tipping is more predictable and it takes less time than bodily movement. The objective of this paper is to demonstrate the limitations of the panoramic radiograph in the decision making process related extraction in orthodontics. An eleven years old girl with lower anterior crowding of about 5 mm was examined prior to her orthodontic treatment. One possible treatment plan, in order to relieve the crowding, was to extract two lower bicuspids. The other treatment plan was to extract one lower incisor. Clinically, both cuspids were acutely tipped mesially, but were imaged uprighted and parallel to their adjacent teeth in the panoramic radiograph. In order to better understand the cuspids position, a model of the lower arch was prepared, with a similar malocclusion demonstrated by the patient. In the model, the cuspids' metal teeth, invested in wax, were mesially angulated. A panoramic radiograph of the model was then taken. The radiograph of the model shows a parallel position of the incisors, the cuspids and the bicuspids, exactly as was shown in the patient's radiograph. It has been demonstrated that there is a discrepancy between the actual position of the teeth and roots and their position in the panoramic radiograph, especially in the mesiodistal angulation. It was concluded that we should be very cautious when trying to interpret the panoramic radiograph as a tool for root parallelism, and remember the inherent image distortions. This is especially true before deciding which teeth will be extracted, on the basis of "incorrect" tooth angulation. PMID:22991875

386

Peri-implant bone changes following tooth extraction, immediate placement and loading of implants in the edentulous maxilla.  

The aim of this study was to clinically and radiographically evaluate peri-implant bone level changes after rehabilitation of a fully edentulous maxilla by placement of six implants in either fresh extraction sites or healed edentulous ridges up till 18 months after implant placement. Twenty patients with a terminal dentition in the maxillae (11 men, 9 women) received a total of 120 OsseoSpeed implants; 118 implants could be loaded immediately of which 59 were placed in extraction sockets and 59 were placed in healed sites. Within 24 h after surgery, all patients received a chairside-assembled, fibre-reinforced temporary fixed prosthetic reconstruction in occlusion. Six months post-surgery, final screw-retained CoCr (15) or Ti (5) computer numerical control-milled and acrylic-veneered frameworks were placed directly at implant level without interposing abutments. Intraoral radiographs were taken 6 and 18 months after implant placement. Implant survival rate was 100%. Mean marginal bone level was located on average -0.35 mm below the reference point (standard deviation 0.29, range -1.20 to +0.02 mm) 18 months after loading. Whether implants were placed in healed bone sites or fresh extraction sockets did not significantly affect the bone level changes. Furthermore, the use of either CoCr or Ti at the implant level did not significantly affect marginal bone loss. Within the limits of this prospective clinical trial, results seem to indicate that immediate placement and occlusal loading of five to six implants in the edentulous maxilla can be carried out successfully. Whether or not those implants are placed in fresh extraction sockets does not seem to alter the outcome. The present data show a successful 1-year outcome of a treatment protocol involving tooth extraction immediately combined with implant placement and loading. PMID:21932023

387

Influences of molar loss of rat on learning and memory  

Purpose: The maxillary unilateral or bilateral molars of rats were extracted, and the influences of the partial loss of occlusal support were evaluated using an 8-arm radial maze and a step-through type passive-avoidance apparatus. Methods: Rats were randomly allocated to three groups not undergoing molar extraction or undergoing extraction of the maxillary unilateral or bilateral molars. Each group was further divided into two groups for maze or passive-avoidance experiments. Thus, a total of six groups were established. The maze experiment was conducted once daily for 10 days. The number of correct choices, number of errors, and the trial time were recorded. The passive-avoidance experiment consisted of an acquisition trial and retention trial. In the acquisition trial, rats were placed in a light room, and the response latency until their entry into a dark room was measured. After 24 h, a similar procedure was performed as a retention trial. Results: In the maze experiment, there was no significant difference by all the groups except on the day 1 in the number of correct choices. But bilateral molar loss group, the number of errors were significantly lower than no extraction group on days 1, 2, 3, 4, and 7. In the passive-avoidance experiment, though the response latency in the retention trial was longer than that in the acquisition trial in all three groups, according to the increase in the number of tooth extraction, it became significantly shorter between P1 and P3. Conclusion: These results suggested that molar loss may be a cause of learning/memory impairment.   

388

Validity of staining and marginal ditching as criteria for diagnosis of secondary caries around occlusal amalgam restorations: an in vitro study  

Abstract in portuguese Este estudo determinou a validade de fendas marginais e manchamentos oclusais como critérios para o diagnóstico de cárie adjacente a restaurações de amálgama. Cento e vinte e quatro dentes humanos extraídos, restaurados com amálgama Classe I, foram submetidos a exame clínico em condições padronizadas. Um examinador treinado registrou a presença de fendas na interface dente/restauração, a ocorrência de manchamento cinza-azulado na superfície oclusal e sua r (more) elação com a presença e severidade de lesões secundárias de cárie. Os exames foram repetidos após 4 dias para cálculo da confiabilidade intraexaminador. A inspeção de cortes seriados ao estereomicroscópio foi utilizada como padrão-ouro. Seis dentes foram perdidos durante o estudo. Dos 118 restantes, 19 (16%) apresentaram manchamento oclusal cinza/azulado e 26 apresentavam fendas marginais com largura superior a 0,20 mm, sendo que destes 14 tinham fendas estreitas e 12 fendas amplas. Os critérios de avaliação apresentaram valores de sensibilidade e preditivo positivo extremamente baixos, enquanto a razão de verossimilhança positiva e a razão de verossimilhança negativa evidenciaram que os critérios apresentaram a mesma chance de determinar um resultado positivo ou negativo para um dente doente ou hígido, indistintamente. Pode ser concluído que fendas/valamentos e manchamentos oclusais não se mostraram como critérios válidos para determinar presença de cárie adjacente a restaurações de amálgama. Abstract in english This study determined the validity of marginal ditching and staining as criteria for the diagnosis of secondary caries around amalgam restorations. One hundred and twenty-four Class I amalgam restorations on extracted human teeth were submitted to standardized clinical examinations. A calibrated examiner recorded the presence of ditching in the tooth/restoration interface, the occurrence of bluish-grey staining on the occlusal surface, and their relationship with the pres (more) ence and severity of secondary carious lesions. Examinations were repeated after 4 days to calculate the intra-examiner reliability. Stereomicroscopic inspection of the serial tooth sections was used as the gold-standard. Six teeth were lost during the study. Of the 118 remaining teeth, 19 (16%) showed occlusal bluish-grey staining and 26 showed more than 0.20 mm wide marginal ditches. Of the latter, 14 presented narrow ditches (0.20-0.45 mm), while 12 presented wide ditches (0.45 mm). The evaluation criteria presented low sensitivity and positive predictive values. Positive and negative likelihood ratios showed that the criteria exhibited, indistinctly, the same odds to determine a positive or negative result for a diseased or healthy tooth. It was concluded that marginal ditching and staining were not valid criteria for the diagnosis of secondary caries around occlusal amalgam restorations.

389

Human teeth as historical biomonitors of environmental and dietary lead: some lessons from isotopic studies of 19th and 20th century archival material.  

The lead isotopic composition of various sections (crown, crown base, root) of teeth was determined in specimens collected from 19th century skulls preserved in museum collections and, upon extraction or exfoliation, from humans of known ages residing in Scotland in the 1990s. For most 20th century samples, calculation of accurate crown-complete or root-complete dates of tooth formation ranging from the 1920s to the 1990s enabled comparison of (206)Pb/(207)Pb ratios for teeth sections (crown base root) with corresponding decadally averaged data for archival herbarium Sphagnum moss samples. This showed that the teeth sections had been significantly influenced by incorporation of non-contemporaneous (more recent) lead subsequent to the time of tooth formation, most probably via continuous uptake by dentine. This finding confirmed that separation of enamel from dentine is necessary for the potential of teeth sections as historical biomonitors of environmental (and dietary) lead exposure at the time of tooth formation to be realised. Nevertheless, the mean 19th century value of 1.172+/-0.007 for the (206)Pb/(207)Pb ratio in teeth was very similar to the corresponding mean value of 1.173+/-0.004 for 19th century archival moss, although relative contributions from environmental sources - whether direct, by inhalation/ingestion of dust contaminated by local lead smelting ((206)Pb/(207)Pb~1.17) and coal combustion ((206)Pb/(207)Pb~1.18) emissions, or indirect, through ingestion of similarly contaminated food - and drinking/cooking water contaminated by lead pipes of local origin, cannot readily be determined. In the 20th century, however, the much lower values of the (206)Pb/(207)Pb ratio (range 1.100-1.166, mean 1.126+/-0.013, median 1.124) for the teeth collected from various age groups in the 1990s reflect the significant influence of imported Australian lead of lower (206)Pb/(207)Pb ratio (~1.04) and released to the environment most notably through car-exhaust emissions arising from the use of alkyl lead additives ((206)Pb/(207)Pb~1.06-1.09) in petrol in the U.K. from ca. 1930 until the end of the 20th century. PMID:16752125

390

Editorial.  

An acute dental injury is a frightening experience for its victim. Blood, tears and fear characterize the event. For the dental clinician, often inexperienced in handling these injuries, the traumatized patient brings these features into the dental clinic. Chaos often reigns and the treatment problem seems overwhelming. Clinical treatment decisions can often be made in haste, with aggressive therapy or even worse, tooth loss to follow. Dentists do too much! In a hospital setting, at the emergency service, often the least experienced residents are given the task. These residents have the admirable position of 100% treatment success. Acute treatment is provided and the patient referred to their own dentist. They seldom see the long-term result of either the injury or of their treatment. Because of this lack of follow-up, referral sheets might also be inadequate in its description of the extent of injury or the appropriate follow-up protocol. Hence, communication between the primary and secondary treatment agencies can be lacking. In 1993, I spoke at an international conference on medical law and ethics in Copenhagen, Denmark. In that talk, I pointed out that despite all the malpractice suits that had been tried in the United States, there was not one that was involved with inappropriate treatment or unnecessary tooth loss following dental trauma. There are several reasons for the situation then and why it still exists today. The first is the general public's lack of knowledge about correct dental care and generally complete trust in the dentist's explanation for the extent of injury which led to the given treatment. The second is the mind set of 'defensive medicine or dentistry' that prevails in most countries, often due to the fear of legal repercussions for failed treatment and often due to the need to treat completely, which is enforced by present day casualty insurance coverage, often provided for by employers for their employees. Such programs only offer coverage while a person stays with their job. Once unemployed, insurance coverage is cancelled and whatever treatment is incomplete is considered a preexisting condition by the next insurance program; and as such, must be paid for out of the patient's own pocket, before a new employer-paid insurance can be affected. This would imply that while longer observation periods might be the most prudent strategy following many dental injuries, dental practitioners are often forced to provide definitive treatment prematurely in order to ensure the patient full dental coverage after injury. In 1972, the first edition of Andreasen's traumatic injuries of the teeth was published. This book marked a breakthrough in the understanding of the biology of dental injury. Up to that time, treatment was based on empirical experience and superstition. Teeth, which might have been saved, were often extracted because extraction was the one 'sure' treatment and problematic late healing complications could then be avoided. But in that textbook, injuries were classified and defined systematically. At the same time, the use of calcium hydroxide was described, which made it possible for inflammatory root resorption to be arrested; and teeth could thereby be maintained in the dental arch. We are now in the age of implantology. Dental implants have been shown to be a reliable treatment form for the replacement of lost teeth. However, in the excitement of this innovation, basic biological knowledge has often been forgotten. Clinicians often choose this relatively new form for treatment at the expense of teeth that could be kept if biological treatment principles are respected and, if correct assessment of the extent of injury is made, when the trauma patient is first seen. This assessment is crucially dependent upon correct examination technique and will also provide information concerning long-term tooth survival: Which injuries have a positive long-term prognosis and which injuries will ultimately lead to tooth loss? Courses in dental traumatology are aimed at providing the clinician with the tool

391

The clinical oro-facial findings of an 11-year-old Japanese boy with 47, XYY: A case report  

47, XYY is a sex chromosome-number disorder occurring in males. Pediatric dentists seldom report encountering 47, XYY males, probably because there are no overt signs of the disease. The purpose of this report is to present the clinical oro-facial findings of the case of a 47, XYY boy based on cephalometric analysis and study model examinations as well as micro-CT measurement of tooth mineralization. An 11-year-old Japanese boy was referred to our clinic for extraction of primary teeth because of their prolonged retention. He had 47, XYY disorder, pulmonary hypertension, and slight mental retardation. Cephalometric analysis and study model examinations that included a comparison of tooth size and arch assessments were performed. A further attempt was made to demonstrate the degree of dentin mineralization in primary molars. The boy’s height and weight were normal but his head circumference had exceeded the 94th percentile since 2 years of age. The cephalometric analysis showed an increase in the lower facial height and bimaxillary protrusion with a longer mandible. Study model examination revealed that the mesio-distal crown widths of all erupted primary and permanent teeth were larger than the standard values, except for the mandibular permanent canines. The degree of dentin mineralization was almost normal in the crown and root areas. A profilogram showed an increase in the lower facial height and bimaxillary protrusion with a longer mandible. The dental arch showed a remarkably contracted width but an extended length. The crown width was larger than the standard values, but the distribution of the degree of dentin mineralization differed little from normal.   

392

An in vitro comparison of the shear bond strength of a resin-reinforced glass ionomer cement and a composite adhesive for bonding orthodontic brackets.  

The shear bond strength (SBS) of a light-cured, resin-reinforced glass ionomer and a composite adhesive in combination with a self-etching primer was compared after different setting times to evaluate when orthodontic wires could be placed. Additionally, the fracture site after debonding was assessed using the Adhesive Remnant Index (ARI). Eighty freshly extracted human premolars were used. Twenty teeth were randomly assigned to each of four groups: (1) brackets bonded with Transbond XT with a Transbond Plus etching primer and debonded within 5 minutes; (2) brackets bonded with Fuji Ortho LC and debonded within 5 minutes; (3) brackets bonded as for group 1 and debonded within 15 minutes; (4) brackets bonded as for group 2 and debonded within 15 minutes. The SBS of each sample was determined with an Instron machine. The mean SBS were, respectively: (1) 8.8 +/- 2 MPa; (2) 6.6 +/- 2.5 MPa; (3) 11 +/- 1.6 MPa and (4) 9.6 +/- 1.6 MPa. Interpolating the cumulative fracture probability by means of a Weibull analysis, the 10 per cent probabilities of fracture for the groups were found to be attained for shear stresses of 6.1, 3.1, 8.3 and 7.1 MPa, respectively. Chi-square testing of the ARI scores revealed that the nature of the remnant did not vary significantly with time, but the type of bonding material could generally be distinguished in leaving more or less than 10 per cent of bonding material on the tooth. After debonding, the Transbond system was likely to leave adhesive on at least 10 per cent of the bonded area of the tooth. The present findings indicate that brackets bonded with either Transbond XT in combination with Transbond Plus etching primer and Fuji Ortho LC had adequate bond strength at 5 minutes and were even stronger 15 minutes after initial bonding. PMID:16043469

393

The influence of air polishers on tooth enamel. An in-vitro study.  

This study compares the effect of 4 different air-powder abrasive devices (PWS) (Air-Flow-S1, Clean-Jet, Prophy-Jet 30, Prophy-Unit) on tooth enamel. Freshly extracted bovine teeth were partially embedded in polyurethane, the labial surface ground flat and highly polished. Subsequently the teeth were subjected to the spray from the air-powder abrasive device for 60 s or polished with a prophylactic paste (CCS 170, CCS 250 or Cleanic) for the same length of time. The effects of the different air-powder abrasive systems were tested under multiple adjustments of powder/air and water. In addition the effects of air-powder abrasive systems and prophylactic pastes on several dentin surfaces were measured. The resulting surface textures of the teeth were examined using laser optic profilometry. In this process multiple measurements of roughness as well as tooth erosion were determined. The Clean-Jet led to significantly rougher surfaces than the 3 prophylactic pastes at every setting. The Air-Flow-S1, Prophy-Jet 30 and Prophy-Unit resulted in enamel abrasion that was either less than that caused by the prophylactic pastes or not significantly different at every examined setting. The 3 polishing pastes removed 3.6 microns to 7.2 microns of enamel in 60 s. The Clean-Jet removed significantly more enamel at every setting per unit of time than the prophylactic pastes (up to 0.1 mm/min); therefore routine application of this device is not advised. Enamel abrasion by the Air-Flow-S1, Prophy-Jet 30 and Prophy-Unit was either less than that measured with the prophylactic pastes or not significantly different. However, the Air-Flow-S1 was more abrasive than Cleanic paste at maximum water adjustment. The Air-Flow-S1 removed 641.2 microns/min of dentin compared to 339.6 microns/min by the Prophy-Jet 30. PMID:9505051

394

Forced extrusion for removal of impacted third molars close to the mandibular canal/ Extrusión forzada para extraer los terceros molares impactados cerca del canal mandibular  

Abstract in spanish Los terceros molares inferiores impactados pueden localizarse muy cerca del canal mandibular. Esto constituye un riesgo de lesión del nervio o la arteria, que se localizan dentro del canal. No obstante, el tercer molar impactado puede desplazarse en dirección coronal con ortodoncia, tras ostectomía del hueso suprayacente, y extraerse sin riesgos. La intervención ortodóncica desplaza lentamente el ápice del diente fuera del canal mandibular y reduce la posibilidad de (more) lesión neural. Este método puede ser útil para pacientes de edad avanzada con ápices dentales que se aproximan o en realidad se localizan en el canal mandibular. La técnica necesita un estudio adicional. Hay la posibilidad teórica de lesión neural o arterial a partir del contacto físico del ápice del diente a medida que se desplaza a través del canal mandibular. Abstract in english Impacted mandibular third molars can be located in close proximity to the mandibular canal. This creates a risk for the nerve or artery injury. These are contained in the canal. However, the impacted third molar can be moved coronally by orthodontic means, after removal of overlying bone, and safely extracted. The orthodontic intervention slowly moves the tooth apex away from the mandibular canal and reduces the potential for a neural injury. This method may be useful for (more) older patients with root apices that approximate or are actually located in the mandibular canal. This technique needs further study. There is a theoretical potential for neural or arterial injury from physical contact of the tooth apex as it moves by or through the mandibular canal.

395

Patients with oro-facial clefts have more dental anomalies.  

Data sourcesMedline, BIRME, OVID, Embase reviews and the Cochrane Library. Additional articles of potential relevance were identified by manual searches.Study selectionObservational controlled studies with non-syndromic forms of oral clefts matched for dental anomalies in primary and/or permanent teeth. There were no language restrictions.Data extraction and synthesisTwo authors reviewed all abstracts independently, compared results and reached consensus on inclusion/exclusion. Authors of the included studies were contacted for missing, relevant data. Quality assessment of the studies was carried out using a modified version of the Loney scoring system.(1)ResultsThere were six studies selected for inclusion, none of which assessed as being at low risk of bias; four were rated as having moderate risk of bias and two at high risk of bias. The dental anomalies were collected into three distinct subgroups. Not all studies included each of the subgroups in their data collection: tooth agenesis was recorded in five studies with 1880 participants; supernumerary teeth in three studies with 1342 participants; and morphologic irregularities in four studies with 1502 participants. There were significant associations between patients with isolated oral clefts and tooth agenesis (OR = 12.31; 95% CI 3.75-40.36), presence of supernumerary teeth (OR = 4.99; 95% CI 2.58-9.64) and morphologic irregularities (OR = 5.69; 95% CI 3.96-8.19).ConclusionsThe evidence suggests that individuals who are born with isolated oral clefts are more likely to have dental anomalies in the permanent dentition than those with no oral clefts. PMID:23059923

396

Prevalence of dental caries among a cohort of preschool children living in Gampaha district, Sri Lanka: A descriptive cross sectional study.  

ABSTRACT: BACKGROUND: Dental caries among young children are a global problem. Scant attention is paid towards primary teeth, leading to high prevalence of dental caries. There are only few studies done in Sri Lanka, addressing oral hygiene among preschool children. Scientific evidence is in need to persuade authorities to establish a programme promoting oral hygiene among preschool children. METHODS: A descriptive cross sectional study was conducted in Ragama Medical officer of Health area. Consecutive children between 2 -- 5 years of age, attending child welfare clinics were recruited for the study. Practices related to dental hygiene and socio-economic characteristics were obtained using an interviewer administered questionnaire. Mouth was examined for evidence of dental caries. Data collection and examination were done by two doctors who were trained for this purpose. The data were analysed using SSPS version 16. RESULTS: Total of 410 children were included. None had a routine visits to a dentist. Practices related to tooth brushing were satisfactory. Prevalence of dental caries gradually increased with age to reach 68.8% by 5 years. Mean total decayed-extracted-filled (deft) score for the whole sample was 1.41 and Significant caries index (SIC) was 4.09. Decayed tooth were the main contributor for the deft score and Care index was only 1.55. Girls had a significantly higher prevalence of caries than boys. CONCLUSIONS: Dental care provided for Sri Lankan preschool children appears to be unsatisfactory as prevalence of dental caries among this cohort of preschool children was very high. There is an urgent need to improve dental care facilities for Sri Lankan preschool children. PMID:23148740

397

Osteonecrose maxilofacial induzida por bisfosfonatos em indivíduos com osteoporose/ Bisphosphonate-induced maxillofacial osteonecrosis in osteoporotic individuals  

Abstract in portuguese Osteonecrose dos maxilares relacionada aos bisfosfonatos pode ser uma complicação importante do tratamento da osteoporose a longo prazo. A possibilidade de osteonecrose dos maxilares em pacientes expostos a bisfosfonatos nitrogenados foi descrita pela primeira vez em 2003. Desde então, relatos de casos e estudos retrospectivos demonstraram maiores percentuais de ocorrência de osteonecrose em pacientes que fizeram ou fazem uso de bisfosfonatos. Embora esta complicaçã (more) o possa ser espontânea, os procedimentos invasivos orais têm um papel como fatores de risco associados aos procedimentos odontológicos, tais como as extrações dentárias e cirurgias de outros ossos. Além disso, infecções dentárias e doença periodontal são relatadas como principais fatores de risco para o desenvolvimento de osteonecrose dos maxilares induzida por bisfosfonatos. Por isso, dentistas, clínicos gerais, ortopedistas, geriatras e cirurgiões bucomaxilofaciais precisam estar cientes do problema e trabalhar em um ambiente multidisciplinar, incentivando o diagnóstico precoce e a prevenção de novos casos potenciais. Abstract in english Bisphosphonate-related osteonecrosis of the maxillae may be an important complication of long-term osteoporosis treatment. The possibility of osteonecrosis of the maxillae in patients exposed to nitrogenated bisphosphonates was first described in 2003. Since then, case reports and retrospective studies have demonstrated higher percentages of occurrence of osteonecrosis in patients who have used or are using bisphosphonates. Although this complication may be spontaneous, i (more) nvasive oral procedures have a role as risk factors associated with dental procedures such as tooth extractions and other bone operations. In addition, tooth infections and periodontal disease have been reported to be the main risk factors for development of bisphosphonate-induced osteonecrosis of the maxillae. For this reason, dentists, general clinicians, orthopedists, geriatricians and oral-maxillofacial surgeons need to be aware of this problem and work in a multidisciplinary environment, thereby stimulating early diagnosis and prevention of further potential cases.

398

Retração rápida de caninos associada ao levantamento do seio maxilar/ Rapid canine retraction associated with maxillary sinus lifting  

Abstract in portuguese INTRODUÇÃO: a retração rápida de caninos por distração do ligamento periodontal é uma técnica de movimentação dentária que permite o fechamento de espaço da extração de primeiros pré-molares em um intervalo de 2 ou 3 semanas, proporcionando uma redução significativa no tempo do tratamento ortodôntico. A técnica cirúrgica para realização deste procedimento é relativamente simples, entretanto, nos casos onde o seio maxilar apresenta-se próximo ao á (more) pice radicular de caninos e pré-molares, sempre há o risco de perfuração da membrana desta cavidade. OBJETIVO: o objetivo deste artigo é apresentar, através de um caso clínico, uma modificação na técnica original proposta por Liou e Huang, onde o levantamento do seio maxilar, executado de forma bastante simples, imprimiu maior controle e segurança ao ato cirúrgico necessário para a realização da retração rápida de caninos. CONCLUSÃO: a retração rápida de caninos é um procedimento exeqüível e o levantamento de seio maxilar pode auxiliar na execução do movimento dentário. Abstract in english INTRODUCTION: Rapid canine distalization using distraction of the periodontal ligament is a tooth movement technique that allows to close the space of extraction of first premolars in about 2 or 3 weeks, reducing orthodontic treatment time considerably. The surgical technique for this procedure is reasonably simple, however, during surgery in the maxilla, always exists the risk of sinus injury when the sinus membrane is close to the apex of canines and first premolars. AI (more) M: The aim of this study is to present a case report showing a modification of the original technique proposed by Liou and Huang, where the maxillary sinus membrane lifting procedure was undertaken in a simple way, leaving it intact, and permitting a safer and more controlled protocol to start the rapid canine retraction. CONCLUSION: Rapid canine retraction is a viable procedure and maxillary sinus lifting may be helpful in providing the tooth movement.

399

Efficacy of intraosseous injections of anesthetic in children and adolescents  

Objective: To compare a computerized intraosseous anesthesia system with the conventional oral anesthesia techniques, and analyze the latency and duration of the anesthetic effect and patient preference. Design: A simple-blind prospective study was made between March 2007 and May 2008. Each patient was subjected to two anesthetic techniques: conventional and intraosseous using the Quicksleeper® system (DHT, Cholet, France). A split-mouth design was adopted in which each patient underwent treatment of a tooth with one of the techniques, and treatment of the homologous contralateral tooth with the other technique. The treatments consisted of restorations, endodontic procedures and simple extractions. Results: The study series comprised 12 females and 18 males with a mean age of 36.8 years. The 30 subjects underwent a total of 60 anesthetic procedures. Intraosseous and conventional oral anesthesia caused discomfort during administration in 46.3% and 32.1% of the patients, respectively. The latency was 7.1±2.23 minutes for the conventional technique and 0.48±0.32 for intraosseous anesthesia – the difference being statistically significant. The depth of the anesthetic effect was sufficient to allow the patients to tolerate the dental treatments. The duration of the anesthetic effect in soft tissues was 199.3 minutes with the conventional technique versus only 1.6 minutes with intraosseous anesthesia – the difference between the two techniques being statistically significant. Most of the patients (69.7%) preferred intraosseous anesthesia. Conclusions: The described intraosseous anesthetic system is effective, with a much shorter latency than the conventional technique, sufficient duration of anesthesia to perform the required dental treatments, and with a much lesser soft tissue anesthetic effect. Most of the patients preferred intraosseous anesthesia. Key words:Anesthesia, intraosseous, oral anesthesia, infiltrating, mandibular block, Quicksleeper®. PMID:18424118

400

Various clinical application of phase contrast X-ray  

In biomedical application study using phase contrast X-ray, both sample thickness or density and absorption difference are very important factors in aspects of contrast enhancement. We present experimental evidence that synchrotron hard X-ray are suitable for radiological imaging of biological samples down to the cellular level. We investigated the potential of refractive index radiology using un-monochromatized synchrotron hard X-rays for the imaging of cell and tissue in various diseases. Material had been adopted various medical field, such as apoE knockout mouse in cardiologic field, specimen from renal and prostatic carcinoma patient in urology, basal cell epithelioma in dermatology, brain tissue from autosy sample of pakinson's disease, artificially induced artilrtis tissue from rabbits and extracted tooth from patients of crack tooth syndrome. Formalin and paraffin fixed tissue blocks were cut in 3 mm thickness for the X-ray radiographic imaging. From adjacent areas, 4 ?m thickness sections were also prepared for hematoxylin-eosin staining. Radiographic images of dissected tissues were obtained using the hard X-rays from the 7B2 beamline of the Pohang Light Source (PLS). The technique used for the study was the phase contrast images were compared with the optical microscopic images of corresponding histological slides. Radiographic images of various diseased tissues showed clear histological details of organelles in normal tissues. Most of cancerous lesions were well differentiated from adjacent normal tissues and detailed histological features of each tumor were clearly identified. Also normal microstructures were identifiable by the phase contrast imaging. Tissue in cancer or other disease showed clearly different findings from those of surrounding normal tissue. For the first time we successfully demonstrated that synchrotron hard X-rays can be used for radiological imaging of relatively thick tissue samples with great histological details.

 
 
 
 
401

An observational cohort study on shortened dental arches-clinical course during a period of 27-35 years.  

OBJECTIVES: The objective of this study was to investigate the clinical course of shortened dental arches ('SDA group') compared to SDAs plus removable denture prosthesis ('SDA plus RDP group') and complete dental arches ('CDA group', controls). MATERIALS AND METHODS: Data (numbers of direct and indirect restorations, endodontic treatments, tooth loss and tooth replacements) were extracted from patient records of subjects attending the Nijmegen Dental School who previously participated in a cohort study on shortened dental arches with three to four posterior occluding pairs (POPs). RESULTS: Records of 35 % of the original cohort were retrievable. At the end of the follow-up (27.4?±?7.1 years), 20 out of 23 SDA subjects still had SDA with 3-4 POPs compared to 6 out of 13 for SDA plus RDP subjects (follow-up 32.6?±?7.3 years). Sixteen out of 23 CDA subjects still had CDA; none of them lost more than one POP (follow-up 35.0?±?5.6 years). SDA group lost 67 teeth: 16 were not replaced, 16 were replaced by FDP and 35 teeth (lost in three subjects) replaced by RDP. Mean number of treatments per year in SDA subjects differed not significantly compared to CDA subjects except for indirect restorations in the upper jaw. CONCLUSION: Shortened dental arches can last for 27 years and over. Clinical course in SDA plus RDP is unfavourable, especially when RDP-related interventions are taken into account. CLINICAL RELEVANCE: The shortened dental arch concept seems to be a relevant approach from a cost-effective point of view. Replacement of absent posterior teeth by free-end RDP cannot be recommended. PMID:22744163

402

EPR dosimetry of radiation background in the Urals region  

Method of Electron Paramagnetic Resonance is extensively applied to individual retrospective dosimetry. The background dose is unavoidable component of cumulative absorbed dose in the tooth enamel accumulated during the lifetime of donor. Estimation of incidental radiation dose using tooth enamel needs in extraction of background dose. Moreover, the variation of background doses in the population is a limited factor for reliable detection of additional irradiation especially for low dose level. Therefore the accurate knowledge of the natural background radiation dose is a critical element of EPR studies of exposed populations. In the Urals region the method applies for such two large cohorts as the workers of Mayak (Ozersk citizens) and Techa River riverside inhabitants (rural population). Current study aimed to investigate the Urals radiation background detected by EPR spectrometry. For this aim two group of unexposed Urals residents were separated, viz: citizens of Ozersk and rural inhabitants of Chelyabinsk region. Comparison of two investigated territories has demonstrated that from the point of view of radiation background it is impossible to assume the Urals population as uniform. The reliable difference between the urban and rural residents has been found. The average background doses of Ozersk donors is in average 50 mGy higher than those detected for rural residents. The individual variability of background doses for Osersk has been higher than in the rural results. The difference in background dose levels between two population results in different limits of accidental dose detection and individualization. The doses for 'Mayak' workers (Ozyorsk citizens) can be classed as anthropogenic if the EPR measurements exceed 120 mGy for teeth younger than 40 years, and 240 mGy for teeth older than 70 years. The anthropogenic doses for Techa River residents (rural population) would be higher than 95 mGy for teeth younger than 50 years and 270 mGy for teeth older than 80 years. (authors)

403

Repair of amalgam restorations with conventional and bonded amalgam: an in vitro study/ Reparo de restaurações de amálgama com amálgama adesivo e convencional: estudo in vitro  

Abstract in portuguese OBJETIVO: Avaliar a microinfiltração em restaurações de amálgama com reparo em amálgama ou amálgama adesivo. MÉTODOS: Trinta pré-molares humanos extraídos foram restaurados com amálgama. Simulou-se um defeito nas restaurações reparado com: G1 - amálgama (n=15) (Permite C-SDI); G2 - amálgama adesivo (n=15) (Caulk 34% Condicionador dentário Gel - Dentsply + Prime & Bond 2.1 - Dentsply + Permite C-SDI). Os dentes foram imersos em solução de nitrato de prata (more) a 50%, termociclados e então, secionados longitudinalmente através da restauração e examinados por três examinadores usando um estereomicroscópio. A microinfiltração foi avaliada pela penetração de corante com uma escala de 0 a 4. Diferenças entre os grupos foram verificadas pelos testes Kruskal Wallis e Dunn. RESULTADOS: Na interface reparo/dente, a técnica de reparo com amálgama adesivo foi significativamente mais efetiva, apresentando menor microinfiltração (escore 0=53.3%, P= 0,0012). Já na interface reparo/restauração, houve menor microinfiltração nas restaurações reparadas com amálgama convencional (escore 0=86.7%, P Abstract in english PURPOSE: This study evaluated microleakage on amalgam restorations repaired by amalgam and bonded amalgam. METHODS: Thirty extracted human pre-molars were restored by amalgam. A simulated defect was prepared and assigned to two treatment groups (n=15): G1 - repaired by amalgam (Permite C-SDI); G2 - repaired by bonded amalgam (Caulk 34% Tooth Conditioner Gel - Dentsply + Prime & Bond 2.1 - Dentsply + Permite C- SDI). The teeth were immersed in a 50% silver nitrate solution (more) , thermocycled and then, sectioned longitudinally through the restoration center and examined by 3 examiners using a stereomicroscope. Microleakage was evaluated in a 0-4 scale for dye penetration. Microleakage data were analyzed by Kruskal Wallis and Dunn test. RESULTS: The bonded amalgam technique was significantly the most effective in repair/tooth interfaces sealing (score 0=53.3%, P=0.0012). For repair/restoration interfaces, conventional amalgam was also statistically more effective in the sealing (score 0=86.7%, P

404

Apoptosis in pulp elimination during physiological root resorption in human primary teeth  

Abstract in portuguese Cinqüenta amostras de polpas de dentes humanos hígidos com indicação para extração foram estudadas a fim de verificar a participação da apoptose na eliminação pulpar durante a reabsorção radicular fisiológica. As amostras foram divididas em 2 grupos: um grupo de estudo composto por 30 polpas de dentes decíduos hígidos com reabsorção radicular fisiológica, e um grupo controle composto por 20 polpas de terceiros molares superiores hígidos. Evidências mor (more) fológicas de apoptose, bem como detecção in situ da fragmentação do DNA genômico via reação de TUNEL e também a detecção do padrão internucleossômico de fragmentação do DNA genômico via eletroforese foram observados. O índice apoptótico foi maior no grupo de dentes decíduos (51,01 ± 0,52) quando comparado ao grupo de dentes permanentes (25,32 ± 0,68) (p Abstract in english Pulp samples of 50 healthy human teeth with indication for extraction were examined to evaluate the role of apoptosis in pulp elimination during physiological root resorption. Two groups were formed: a test group (n=30) composed of pulp samples of primary teeth with physiological root resorption and a control group (n=20) composed of pulp samples of permanent maxillary third molars. Morphological evidence of apoptosis as well as in situ detection of cellular DNA fragmenta (more) tion by TUNEL assay and detection of internucleosomal pattern of fragmentation of the genomic DNA by electrophoresis were observed. The apoptotic index of the primary tooth group was significantly higher than that of the permanent tooth group (51.01 ± 0.52 versus 25.32 ± 0.68) (p

405

Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in oral and maxillofacial surgery part 1: Periodontal and dentoalveolar surgery.  

Platelet concentrates for surgical use are innovative tools of regenerative medicine, and were widely tested in oral and maxillofacial surgery. Unfortunately, the literature on the topic is contradictory and the published data are difficult to sort and interpret. In periodontology and dentoalveolar surgery, the literature is particularly dense about the use of the various forms of Platelet-Rich Plasma (PRP) - Pure Platelet-Rich Plasma (P-PRP) or Leukocyte- and Platelet-Rich Plasma (L-PRP) - but still limited about Platelet-Rich Fibrin (PRF) subfamilies. In this first article, we describe and discuss the current published knowledge about the use of PRP and PRF during tooth avulsion or extraction, mucogingival surgery, Guided Tissue Regeneration (GTR) or bone filling of periodontal intrabony defects, and regeneration of alveolar ridges using Guided Bone Regeneration (GBR), in a comprehensive way and in order to avoid the traps of a confusing literature and to highlight the underlying universal mechanisms of these products. Finally, we particularly insist on the perspectives in this field, through the description and illustration of the systematic use of L-PRF (Leukocyte- and Platelet- Rich Fibrin) clots and membranes during tooth avulsion, cyst exeresis or the treatment of gingival recessions by root coverage. The use of L-PRF also allowed to define new therapeutic principles: NTR (Natural Tissue Regeneration) for the treatment of periodontal intrabony lesions and Natural Bone Regeneration (NBR) for the reconstruction of the alveolar ridges. In periodontology, this field of research will soon find his golden age by the development of user-friendly platelet concentrate procedures, and the definition of new efficient concepts and clinical protocols. PMID:21740371

406

Neural crest stem cell property of apical pulp cells derived from human developing tooth.  

Recent reports have described that NCSCs (neural crest-derived stem cells) are not only present in the embryonic neural crest but also in the adult tissues. Dental pulp is one of mesenchymal soft tissues origin from cranial neural crest cells, and thought to be a source of adult stem cells. Here, we investigated the existence of NCSC-like cells in apical pulp of human developing tooth. Human impacted third molars with immature apex freshly extracted were obtained. The cells derived from the apical pulp tissue not framed by dentin or the coronal pulp tissues were cultured by primary explant culture. APDCs (apical pulp-derived cells) and CPCs (coronal pulp cells) formed spheres under neurosphere culture condition. The number of spheres from APDCs was larger than that from CPCs. The sphere-forming cells derived from APDCs had self-renewal capacity, and expressed neural crest-associated markers (p75, Snail and Slug) and NSC (neural stem cell) markers (Nestin and Musashi1). The expression pattern of mesenchymal stem cell markers, CD105 and CD166, on the surface of sphere-forming cells derived APDCs was different from that of APDCs. These sphere-forming cells could differentiate into multiple mesenchymal lineages (osteoblasts, adipocytes, chondrocytes and smooth muscle cells) and neural lineage (neurons) in vitro, and generated ectopic bone tissues on the border of HA (hydroxyapatite) scaffold in vivo. The results of this study suggest that APDCs contain cells with characteristics of NCSCs reported previously in mice. Humans developing tooth with immature apex is an effective source of cells for neural crest lineage tissue regeneration. PMID:22731688

407

Morphological characterization of the tooth/adhesive interface  

Abstract in portuguese Este estudo teve o objetivo de observar a morfologia da interface dente-restauração de diferentes sistemas adesivos em cavidades MOD, por microscopia eletrônica de varredura (MEV). A hipótese do estudo foi de que a morfologia da interface adesiva poderia variar nas diferentes regiões da cavidade MOD, para algum dos 3 sistemas adesivos estudados. Preparos tipo MOD foram confeccionados em 12 terceiros molares humanos hígidos e restaurados com resina composta Filtek Z2 (more) 50 e os seguintes sistemas adesivos: ABF (n=4), Clearfil SE Bond (n=4) (sistemas adesivos autocondicionantes) e Single Bond (n=4) (sistema adesivo de condicionamento ácido total). Após 24 h de armazenamento em água destilada a 37ºC, os dentes foram secionados e preparados para MEV. A morfologia da interface de união variou com o sistema adesivo e com a região analisada. A hipótese do estudo foi aceita, pois a morfologia da interface de união refletiu as características do substrato dental e dos sistemas adesivos testados. Abstract in english The purpose of this study was to assess the morphological characteristics of the tooth/adhesive interface using different adhesive systems in MOD restorations under scanning electron microscopy (SEM). The tested hypothesis was that the morphology of the bonding interface would vary in different areas of MOD restorations for the three adhesive systems. MOD cavities were prepared in 12 sound extracted human third molars and restored with Filtek Z250 composite resin and one (more) of the following adhesive systems: Experimental ABF (n=4), Clearfil SE Bond (n=4) self-etching primers and Single Bond etch-and-rinse adhesive system (n=4). After 24-h storage in distilled water at 37ºC, teeth were sectioned and prepared for SEM. The interfacial morphology varied depending on the adhesive system and also on the evaluated area. The null hypothesis was accepted because the morphology of the tooth/adhesive interface reflected the characteristics of both the dental substrate and the adhesive systems.

408

A study of mandibular foramen and mandibular canal using orthopantomograms  

The mandibular canal must be considered carefully during surgical treatment, especially surgical extraction of the impacted tooth and intraosseous implant because it contains the important inferior alveolar nerve and vessel. Th e author investigated the curvature of the mandibular canal, the positional frequency of mandibular foramen to the occlusal plane and gonial angle and the positional frequency of the mental foramen to the tooth site using orthopantomorgrams. The materials considered of 295 orthopantomograms divided into seven groups ranging from the first decade to 6th decade. The results were as follows: 1. The position of mandibular foramen was most frequently below occlusal plane in Group I (78.6%) and Group II (71.2%) , above occlusal plane in Group III (63.0%), Group IV (71.1%), Group V (57.6%), Group VI (76.7%) and Group VII (70.0%). 2. The curvature of mandibular canal was 142.82 .deg. in Group I, 142.09 .deg. in Group II, 139.34 .deg. in Group III, 141.48 .deg. in Group IV, 138.45 .deg. in Group V, 140.77 .deg. in Group VI and 143.89 .deg. in Group VII. 3. The gonial angle was 125.82 .deg. in Group I, 123.18 .deg. in Group II, 124.06 .deg. in Group III, 120.45 .deg. in Group IV, 121.12 .deg. in Group V, 121.63 .deg. in Group VI and 121.24 .deg. in Group VII. 4. The position of the mental foramen was most frequently below the apex of mandibular first premolar in Group I (57.2%), between the apex of mandibular first and second premolar in Group II (59.6%) and Group III (48.9%), and below the apex of mandibular second premolar in Group IV (39.2%), Group V (48.5%) Group VI (46.7%) and Group VII (56.4%).

409

The role of the dental lamina in mammalian tooth replacement  

We have applied the ferret, Mustela putorius furo, as a model for tooth replacement. Ferret has a heterodont dentition, which includes all tooth families, and all antemolar teeth are replaced. Compared with mouse, the ferret therefore has a less derived mammalian dentition resembling that of humans. We have studied tooth replacement in serial histological sections in embryonic and young postnatal ferrets. Our observations indicate that the replacement teeth form from the dental lamina that is intimately connected to the lingual aspect of the deciduous tooth enamel organ. It grows as an offshoot from the enamel organ, elongates in cervical direction and later buds to give rise to the replacement tooth. The extent of the dental lamina growth, preceding replacement tooth budding, varied betwe...

410

Exogenous fibroblast growth factor 8 rescues development of mouse diastemal vestigial tooth ex vivo  

Abstract Regression of vestigial tooth buds results in the formation of the toothless diastema, a unique feature of the mouse dentition. Revitalization of the diastemal vestigial tooth bud provides an excellent model for studying tooth regeneration and replacement. It has been previously shown that suppression of fibroblast growth factor (FGF) signaling in the diastema results in vestigial tooth bud regression. In this study, we report that application of exogenous FGF8 to the mouse embryonic diastemal region rescues diastemal tooth development. However, this rescue of diastemal tooth development occurs only in an isolated diastemal regions and not in the mandibular quadrant, which includes the incisor and molar germs. FGF8 promotes cell proliferation and inhibits apoptosis in diastemal to...

411

In-vitro regulation of odontogenic gene expression in human embryonic tooth cells and SHED cells.  

The bud-to-cap stage transition during early tooth development is a time when the tooth-inducing potential becomes restricted to the mesenchyme. Several key genes, expressed in the mesenchyme at this stage, are an absolute requirement for the progression of tooth development. These include the transcription factors Msx1 and Pax9. The inductive potential of tooth mesenchyme cells is a key requisite for whole-tooth bioengineering and thus identification of cells that can retain this property following expansion in culture is an important as yet unresolved, goal. We show here that in-vitro culture of embryonic human tooth mesenchyme cells and SHED cells express low levels of PAX9 and MSX1 and that these levels can be significantly upregulated by activation of different signalling pathways. Such in-vitro manipulation may thus offer a simple way of maintaining/restoring/inducing the odontogenic-inducing capacity in mesenchymal cells. PMID:22427065

412

Tooth loss in aggressive periodontitis after active periodontal therapy: patient-related and tooth-related prognostic factors  

Abstract Objectives: To assess prognostic factors for tooth loss after active periodontal therapy (APT) in patients with aggressive periodontitis (AgP) at tooth level. Material and methods: Eighty-four patients with AgP were re-evaluated after a mean period of 10.5 years of supportive periodontal therapy (SPT). Two thousand and fifty-four teeth were entered into the model. The tooth-related factors including baseline bone loss, tooth location and type, furcation involvement (FI), regenerative therapy, and abutment status, as well as time of follow-up and other patient-related factors were tested for their prognostic value at tooth level. Multilevel regression analysis was performed for statistical analysis to identify factors contributing to tooth loss. Results: During SPT, 113 teeth (1.34...

413

Gear noise origins  

Each pair of meshing gears in a transmission gives rise to a source of vibratory excitation that can result in the radiation of sound. Each such source is most conveniently characterized as a displacement form of excitation generally referred to as the static transmission error of the gear pair. Contributions to the frequency spectrum of the static transmission error of spur and helical gears arising from tooth and gear body elastic deformations and from deviations of tooth surfaces from perfect involute surfaces are considered. Tooth surface deviations are decomposed into contributions giving rise to tooth meshing harmonic excitations and rotational harmonic or sideband excitations. Various types of gear tooth errors are defined and the contributions of these errors to different parts of the frequency spectrum are described. The attenuating effect on the static transmission error spectrum arising from the smoothing action of multiple tooth contact is explained.

414

Sonocatalytic damage of bovine serum albumin (BSA) under ultrasonic irradiation with TiO2/tooth composite  

Abstract BACKGROUND: In order to effectively degrade bovine serum albumin (BSA) under ultrasonic irradiation, biological mineral material (tooth powder) was adopted to mix with nano-sized TiO2 powder. A TiO2/tooth composite with high sonocatalytic activity and remarkable selectivity was prepared. RESULTS: TiO2/tooth composite with tooth content of 30% (w/w) heat-treated at 500 C for 40 min was used as sonocatalyst and the catalytic degradation of BSA under ultrasonic irradiation was examined. Some influencing factors, such as ultrasonic irradiation time, TiO2/tooth catalyst amount, solution acidity and NaCl concentration, were studied by UV-vis and fluorescence spectroscopic analysis. Furthermore, the BSA attack site for the TiO2/tooth composite was identifies by synchronous fluorescence s...

415

Diverse Function of Epiprofin in Tooth Development  

The developing tooth is a good model for studying the mechanism of organogenesis. Tooth development begins as the placode formation with the thickening and invaginating of the oral ectoderm into the dental mesenchyme. A series of reciprocal interactions between these two cell types give rise to differentiation into various cell types including epithelial-derived enamel-secreting ameloblasts and neural crest-derived dentin-secreting odontoblasts. A number of transcription factors control tooth development in order to form unique structures specialized for tooth function with optimized shapes and sizes. We identified Epiprofin (Epfn) as a transcription factor preferentially expressed in teeth. Epfn KO mice display profound embryonic and postnatal growth retardation and develop impaired hair follicle and whisker formation. The drastic phenotypes of Epfn KO are supernumerary tooth formation and lack of enamel in teeth. These observations suggest that Epiprofin plays critical roles in ectodermal organ development and regulates the number of teeth. This review summarizes the roles of Epiprofin in tooth development.   

416

Osteopatologias e alterações dentárias em Otaria byronia (Pinnipedia, Otariidae) da costa do Rio Grande do Sul, Brasil/ Osteopathologies and tooth alterations in Otaria byronia (Pinnipedia, Otariidae) from Rio Grande do Sul coast, Brazil  

Abstract in english Bone diseases and tooth alterations in 47 specimens of Otaria byronia (Blainville, 1820), from southern Brazilian coast, were analized. Tooth wear and the associated bone pathologies were determined, as well as their percentuals. The main infection was osteomyelitis associated with tooth alterations, such as fractures and attrition, both of them exposing the pulp chamber. Tooth attrition increases with age, favoring fractures and their complications, including osteomyelit (more) is, causing a high frequency of them in specimens presenting more pronounced tooth wear. In one specimen tuberculosis was found in the maxilla, perhaps primarily pulmonary. The high frequency of enamel hypoplasia might reflect cyclic food deficit. Infections and tooth fractures might be related to behaviour, such as fishermen interaction, territorial fighting, and accidents during food capture.

417

Kinematics Modeling and Experimentation of the Multi-manipulator Tooth-Arrangement Robot for Full Denture Manufacturing  

Artificial teeth are very complicated in shape, and not easy to be grasped and manipulated accurately by a single robot. The method of tooth-arrangement by multi-manipulator for complete denture manufacturing proposed in this paper. A novel complete denture manufacturing mechanism is designed based on multi-manipulator and dental arch generator. Kinematics model of the multi-manipulator tooth-arrangement robot is built by analytical method based on tooth-arrangement principle for full denture. Preliminary experiments on tooth-arrangement are performed using the multi-manipulator tooth-arrangement robot prototype system. The multi-manipulator tooth-arrangement robot prototype system can automatically design and manufacture a set of complete denture that is suitable for a patient according t...

418

Development of a multi-layered virtual tooth model for the haptic dental training system  

A virtual reality (VR) haptic dental training system could be a promising tool for future dental education. One major challenge is to develop a virtual tooth model which similarly reflected a real tooth having multiple layers with different mechanical hardness in each layer. The multi-layered virtual