WorldWideScience
 
 
1

The APS machine protection system (MPS)  

International Nuclear Information System (INIS)

The machine protection system (MPS) that protects the APS storage ring vacuum chamber from x-ray beams, is active. There are over 650 sensors monitored and networked through the MPS system. About the same number of other process variables are monitored by the much slower EPICS control system, which also has an input to the rf abort chain. The MPS network is still growing with the beam position limits detection system coming on-line. The network configuration, along with a limited description of individual subsystems, is presented

2

MULTIPLE PROJECTS SYSTEM (MPS) VERSION 2.0 - USER'S MANUAL  

Science.gov (United States)

The document is a user's manual for Multiple Projections System (MPS) Version 2.0, based on the 3% reasonable further progress (RFP) tracking system that was developed in FY92/FY93. he 3% RFP tracking system is a Windows application, and enhancements to convert the 3% RFP trackin...

3

MULTIPLE PROJECTIONS SYSTEM (MPS): USER'S MANUAL VERSION 2.0  

Science.gov (United States)

The document is a user's manual for Multiple Projections System (MPS) Version 2.0, based on the 3% reasonable further progress (RFP) tracking system that was developed in FY92/FY93. The 3% RFP tracking system is a Windows application, and enhancements to convert the 3% RFP track...

4

mps discussion  

The Marine Policy Statement (MPS) will be the first part of new systems of marine \\... outline IA sets out the need for a more strategic marine planning system to ...... \\monuments, sites, or landscapes of historic, archaeological, architectural ..... and \\many fish, sound is important to communicate to local mates, to search for prey,.

5

A New Numerical Approach Toward MPS State on Spin Ladder Systems  

Science.gov (United States)

The matrix product state (MPS) representation used by DMRG is extremely effective in 1D, but loses effectiveness exponentially with the width in ladder systems. Tensor product wavefunction, such as PEPS, are efficient representations of 2D states but calculations utilizing them are very inefficient. As an intermediate approach between these, we consider a wavefunction consisting of an MPS multiplied by local bond exponentials ^-?Hbond applied on adjacent sites in the lattice which appear distant in the MPS. The exponentials restore the area law to the MPS. For efficient calculation, the bond-exponentials are transferred to the Hamiltonian in a matrix product operator representation, acting as a similarity transformation, preserving the eigenvalues. For this method to be successful, not only should the modified MPS representation be efficient, the MPO representation of the transformed Hamiltonian should have a small matrix dimension. We report on preliminary results on ladders with several legs for this approach.

Zhu, Zhenyue; White, Steven

2010-03-01

6

DET/MPS - THE GSFC ENERGY BALANCE PROGRAM, DIRECT ENERGY TRANSFER/MULTIMISSION SPACECRAFT MODULAR POWER SYSTEM (UNIX VERSION)  

Science.gov (United States)

The DET/MPS programs model and simulate the Direct Energy Transfer and Multimission Spacecraft Modular Power System in order to aid both in design and in analysis of orbital energy balance. Typically, the DET power system has the solar array directly to the spacecraft bus, and the central building block of MPS is the Standard Power Regulator Unit. DET/MPS allows a minute-by-minute simulation of the power system's performance as it responds to various orbital parameters, focusing its output on solar array output and battery characteristics. While this package is limited in terms of orbital mechanics, it is sufficient to calculate eclipse and solar array data for circular or non-circular orbits. DET/MPS can be adjusted to run one or sequential orbits up to about one week, simulated time. These programs have been used on a variety of Goddard Space Flight Center spacecraft projects. DET/MPS is written in FORTRAN 77 with some VAX-type extensions. Any FORTRAN 77 compiler that includes VAX extensions should be able to compile and run the program with little or no modifications. The compiler must at least support free-form (or tab-delineated) source format and 'do do-while end-do' control structures. DET/MPS is available for three platforms: GSC-13374, for DEC VAX series computers running VMS, is available in DEC VAX Backup format on a 9-track 1600 BPI tape (standard distribution) or TK50 tape cartridge; GSC-13443, for UNIX-based computers, is available on a .25 inch streaming magnetic tape cartridge in UNIX tar format; and GSC-13444, for Macintosh computers running AU/X with either the NKR FORTRAN or AbSoft MacFORTRAN II compilers, is available on a 3.5 inch 800K Macintosh format diskette. Source code and test data are supplied. The UNIX version of DET requires 90K of main memory for execution. DET/MPS was developed in 1990. A/UX and Macintosh are registered trademarks of Apple Computer, Inc. VMS, DEC VAX and TK50 are trademarks of Digital Equipment Corporation. UNIX is a registered trademark of AT&T Bell Laboratories.

Jagielski, J. M.

1994-01-01

7

FEDERAL USERS CONFERENCE PRODUCT LINE TOOL SET (PLTS) MAP PRODUCTION SYSTEM (MPS) ATLAS CUSTOM GRIDS [Rev 0 was draft  

International Nuclear Information System (INIS)

Maps, and more importantly Atlases, are assisting the user community in managing a large land area with complex issues, the most complex of which is the management of nuclear waste. The techniques and experiences discussed herein were gained while developing several atlases for use at the US Department of Energy's Hanford Site. The user community requires the ability to locate not only waste sites, but other features as well. Finding a specific waste site on a map and in the field is a difficult task at a site the size of Hanford. To find a specific waste site, the user begins by locating the item or object in an index, then locating the feature on the corresponding map within an atlas. Locating features requires a method for indexing them. The location index and how to place it on a map or atlas is the central theme presented in this article. The user requirements for atlases forced the design team to develop new and innovative solutions for requirements that Product Line Tool Set (PLTS) Map Production System (MPS)-Atlas was not designed to handle. The layout of the most complex atlases includes custom reference grids, multiple data frames, multiple map series, and up to 250 maps. All of these functional requirements are at the extreme edge of the capabilities of PLTS MPS-Atlas. This document outlines the setup of an atlas using PLTS MPS-Atlas to meet these requirements

8

FEDERAL USERS CONFERENCE PRODUCT LINE TOOL SET (PLTS) MAP PRODUCTION SYSTEM (MPS) ATLAS CUSTOM GRIDS [Rev 0 was draft  

Energy Technology Data Exchange (ETDEWEB)

Maps, and more importantly Atlases, are assisting the user community in managing a large land area with complex issues, the most complex of which is the management of nuclear waste. The techniques and experiences discussed herein were gained while developing several atlases for use at the US Department of Energy's Hanford Site. The user community requires the ability to locate not only waste sites, but other features as well. Finding a specific waste site on a map and in the field is a difficult task at a site the size of Hanford. To find a specific waste site, the user begins by locating the item or object in an index, then locating the feature on the corresponding map within an atlas. Locating features requires a method for indexing them. The location index and how to place it on a map or atlas is the central theme presented in this article. The user requirements for atlases forced the design team to develop new and innovative solutions for requirements that Product Line Tool Set (PLTS) Map Production System (MPS)-Atlas was not designed to handle. The layout of the most complex atlases includes custom reference grids, multiple data frames, multiple map series, and up to 250 maps. All of these functional requirements are at the extreme edge of the capabilities of PLTS MPS-Atlas. This document outlines the setup of an atlas using PLTS MPS-Atlas to meet these requirements.

HAYENGA, J.L.

2006-12-19

9

Development of a Lagrangian Meshless Flow Solver based on the Moving Particle Semi-implicit (MPS) Method  

Science.gov (United States)

This paper discusses on the development of a meshless flow solver based on the Lagrangian particle method. The differential operators are discretised by using the particle interaction models proposed in the numerical framework of the Moving Particle Semi-implicit (MPS) technique. The MPS method is attractive from the viewpoint of no mesh is required and fluid is purely represented by points (the virtue of meshless algorithm). Some flow applications attempted by the current meshless solver will be shown and results are compared with the published experimental data.

Ng, K. C.; Ng, Y. L.; Yusoff, M. Z.

2013-06-01

10

Development of a Lagrangian Meshless Flow Solver based on the Moving Particle Semi-implicit (MPS) Method  

International Nuclear Information System (INIS)

This paper discusses on the development of a meshless flow solver based on the Lagrangian particle method. The differential operators are discretised by using the particle interaction models proposed in the numerical framework of the Moving Particle Semi-implicit (MPS) technique. The MPS method is attractive from the viewpoint of no mesh is required and fluid is purely represented by points (the virtue of meshless algorithm). Some flow applications attempted by the current meshless solver will be shown and results are compared with the published experimental data.

11

DET/MPS - THE GSFC ENERGY BALANCE PROGRAM, DIRECT ENERGY TRANSFER/MULTIMISSION SPACECRAFT MODULAR POWER SYSTEM (DEC VAX VMS VERSION)  

Science.gov (United States)

The DET/MPS programs model and simulate the Direct Energy Transfer and Multimission Spacecraft Modular Power System in order to aid both in design and in analysis of orbital energy balance. Typically, the DET power system has the solar array directly to the spacecraft bus, and the central building block of MPS is the Standard Power Regulator Unit. DET/MPS allows a minute-by-minute simulation of the power system's performance as it responds to various orbital parameters, focusing its output on solar array output and battery characteristics. While this package is limited in terms of orbital mechanics, it is sufficient to calculate eclipse and solar array data for circular or non-circular orbits. DET/MPS can be adjusted to run one or sequential orbits up to about one week, simulated time. These programs have been used on a variety of Goddard Space Flight Center spacecraft projects. DET/MPS is written in FORTRAN 77 with some VAX-type extensions. Any FORTRAN 77 compiler that includes VAX extensions should be able to compile and run the program with little or no modifications. The compiler must at least support free-form (or tab-delineated) source format and 'do do-while end-do' control structures. DET/MPS is available for three platforms: GSC-13374, for DEC VAX series computers running VMS, is available in DEC VAX Backup format on a 9-track 1600 BPI tape (standard distribution) or TK50 tape cartridge; GSC-13443, for UNIX-based computers, is available on a .25 inch streaming magnetic tape cartridge in UNIX tar format; and GSC-13444, for Macintosh computers running AU/X with either the NKR FORTRAN or AbSoft MacFORTRAN II compilers, is available on a 3.5 inch 800K Macintosh format diskette. Source code and test data are supplied. The UNIX version of DET requires 90K of main memory for execution. DET/MPS was developed in 1990. A/UX and Macintosh are registered trademarks of Apple Computer, Inc. VMS, DEC VAX and TK50 are trademarks of Digital Equipment Corporation. UNIX is a registered trademark of AT&T Bell Laboratories.

Jagielski, J. M.

1994-01-01

12

DET/MPS - THE GSFC ENERGY BALANCE PROGRAM, DIRECT ENERGY TRANSFER/MULTIMISSION SPACECRAFT MODULAR POWER SYSTEM (MACINTOSH A/UX VERSION)  

Science.gov (United States)

The DET/MPS programs model and simulate the Direct Energy Transfer and Multimission Spacecraft Modular Power System in order to aid both in design and in analysis of orbital energy balance. Typically, the DET power system has the solar array directly to the spacecraft bus, and the central building block of MPS is the Standard Power Regulator Unit. DET/MPS allows a minute-by-minute simulation of the power system's performance as it responds to various orbital parameters, focusing its output on solar array output and battery characteristics. While this package is limited in terms of orbital mechanics, it is sufficient to calculate eclipse and solar array data for circular or non-circular orbits. DET/MPS can be adjusted to run one or sequential orbits up to about one week, simulated time. These programs have been used on a variety of Goddard Space Flight Center spacecraft projects. DET/MPS is written in FORTRAN 77 with some VAX-type extensions. Any FORTRAN 77 compiler that includes VAX extensions should be able to compile and run the program with little or no modifications. The compiler must at least support free-form (or tab-delineated) source format and 'do do-while end-do' control structures. DET/MPS is available for three platforms: GSC-13374, for DEC VAX series computers running VMS, is available in DEC VAX Backup format on a 9-track 1600 BPI tape (standard distribution) or TK50 tape cartridge; GSC-13443, for UNIX-based computers, is available on a .25 inch streaming magnetic tape cartridge in UNIX tar format; and GSC-13444, for Macintosh computers running AU/X with either the NKR FORTRAN or AbSoft MacFORTRAN II compilers, is available on a 3.5 inch 800K Macintosh format diskette. Source code and test data are supplied. The UNIX version of DET requires 90K of main memory for execution. DET/MPS was developed in 1990. A/UX and Macintosh are registered trademarks of Apple Computer, Inc. VMS, DEC VAX and TK50 are trademarks of Digital Equipment Corporation. UNIX is a registered trademark of AT&T Bell Laboratories.

Jagielski, J. M.

1994-01-01

13

J-PARC accelerator MPS functionality for high availability  

International Nuclear Information System (INIS)

In this paper, the project to improve J-PARC MPS (Machine Protection System) will be reported. Current J-PARC MPS stops the delivery of the beam to all J-PARC complex, when MPS events from any components in the system is triggered. MLF (Material and Life science Facility) receives beams from RCS directly. Some of MPS events in MR, HD (Hadron Facility) or NU (Neutrino Facility) does not affect the quality of beams to MLF at all. These events should not stop the delivery of the beam to MLF. We designed a new or improve J-PARC MPS to accept two levels of MPS signal from MR, HD and NU. In the new MPS system, some MPS events, classified as 'MR Inhibit', prevents the delivery of the beam to MR but allows the delivery of the beam to MLF. The design of this new MPS and the status of the installation is described in this report. (author)

14

National MPS Society (Mucopolysaccharidoses)  

Science.gov (United States)

... the body uses enzymes to break down and recycle materials in cells. In individuals with MPS and ... Planned Giving Gifts You Make Today Gifts That Benefit the Society After Your Lifetime Society Priorities & Giving ...

15

Development of MPS IVA mouse (Galnstm(hC79S.mC76S)slu) tolerant to human N-acetylgalactosamine-6-sulfate sulfatase.  

Science.gov (United States)

Mucopolysaccharidosis IVA (MPS IVA) is an autosomal recessive disease caused by N-acetylgalactosamine-6-sulfate sulfatase (GALNS) deficiency. In recent studies of enzyme replacement therapy for animal models with lysosomal storage diseases, cellular and humoral immune responses to the injected enzymes have been recognized as major impediments to effective treatment. To study the long-term effectiveness and side effects of therapies in the absence of immune responses, we have developed an MPS IVA mouse model, which has many similarities to human MPS IVA and is tolerant to human GALNS protein. We used a construct containing both a transgene (cDNA) expressing inactive human GALNS in intron 1 and an active site mutation (C76S) in adjacent exon 2 and thereby introduced both the inactive cDNA and the C76S mutation into the murine Galns by targeted mutagenesis. Affected homozygous mice have no detectable GALNS enzyme activity and accumulate glycosaminoglycans in multiple tissues including visceral organs, brain, cornea, bone, ligament and bone marrow. At 3 months, lysosomal storage is marked within hepatocytes, reticuloendothelial Kupffer cells, and cells of the sinusoidal lining of the spleen, neurons and meningeal cells. The bone storage is also obvious, with lysosomal distention in osteoblasts and osteocytes lining the cortical bone, in chondrocytes and in the sinus lining cells in bone marrow. Ubiquitous expression of the inactive human GALNS was also confirmed by western blot using the anti-GALNS monoclonal antibodies newly produced, which resulted in tolerance to immune challenge with human enzyme. The newly generated MPS IVA mouse model should provide a good model to evaluate long-term administration of enzyme replacement. PMID:16219627

Tomatsu, Shunji; Gutierrez, Monica; Nishioka, Tatsuo; Yamada, Masamichi; Yamada, Mana; Tosaka, Yasuhiro; Grubb, Jeffrey H; Montaño, Adriana M; Vieira, Matheus B; Trandafirescu, Georgeta G; Peña, Olga M; Yamaguchi, Seiji; Orii, Koji O; Orii, Tadao; Noguchi, Akihiko; Laybauer, Leticia

2005-11-15

16

Classifying quantum phases using MPS and PEPS  

Digital Repository Infrastructure Vision for European Research (DRIVER)

We apply the framework of Matrix Product States (MPS) and Projected Entangled Pair States (PEPS) and their associated parent Hamiltonians to the classification of quantum phases in one and higher dimensions, where we define two systems to be in the same phase if they can be connected via a path of gapped Hamiltonians. In one dimension, we prove that any two Hamiltonians with MPS ground states are in the same phase if and only if they have the same ground state degeneracy. Subse...

Schuch, Norbert; Pe?rez Garci?a, David; Cirac, Ignacio

2010-01-01

17

Development of the machine protection system for LCLS-I  

International Nuclear Information System (INIS)

Machine Protection System (MPS) requirements for the currently operating Linac Coherent Light Source (LCLSI) demand that fault detection and mitigation occur within one machine pulse (1/120 of a second at full beam rate). The MPS must handle inputs from a variety of sources including loss monitors as well as standard state-type inputs. These sensors exist at various places across the full 2.5 Km length of the accelerator and beam lines. A new MPS has been developed based on a distributed star network where custom-designed local hardware nodes handle sensor inputs and mitigation outputs for localized regions of the LCLS accelerator complex. These Link- Nodes report status information and receive action commands from a centralized processor running the MPS algorithm over a private network. The individual Link-Node is a 3u chassis with configurable hardware components that can be setup with digital and analog inputs and outputs, depending upon the sensor and actuator requirements. Features include a custom MPS digital input/output subsystem, a private Ethernet interface, an embedded processor, a custom MPS engine implemented in an FPGA and an Industry Pack (IP) bus interface, allowing COTS and custom analog/digital I/O modules to be utilized for MPS functions. These features, while capable of handling standard MPS state-type inputs and outputs, allow other systems like beam loss monitors to be completely integrated within it. To date, four different types of Link-Nodes are in use in LCLS-I. This paper describes the design, construction and implementation of the LCLS MPS with a focus on the Link-Node, which has proven to be a very useful and flexible component for the MPS. (authors)

18

RoMPS concept review automatic control of space robot  

Science.gov (United States)

The Robot operated Material Processing in Space (RoMPS) experiment is being performed to explore the marriage of two emerging space commercialization technologies: materials processing in microgravity and robotics. This concept review presents engineering drawings and limited technical descriptions of the RoMPS programs' electrical and software systems.

1991-01-01

19

An overview of Korean patients with mucopolysaccharidosis and collaboration through the Asia Pacific MPS Network.  

Science.gov (United States)

Mucopolysaccharidosis (MPS) is a constellation of disorders characterized by the accumulation of mucopolysaccharides in tissues and organs. This accumulation results in the deterioration and degeneration of multiple organs. This paper describes the general distribution of types of MPS in patients, their clinical characteristics and genotypes, the development of animal studies and preclinical studies, enzyme replacement therapy in South Korea, and the development of idursulfase beta and clinical trials on idursulfase beta in South Korea. In addition, this paper discusses academic collaboration among specialists in MPS care in the Asia-Pacific region, which includes Japan, Taiwan, Malaysia, and South Korea, through an organization called the Asia-Pacific MPS Network (APMN). The Asia-Pacific MPS Registry, an electronic remote data entry system, has been developed by key doctors in the APMN. Rare diseases require international cooperation and collaboration to elucidate their mechanisms and carry out clinical trials; therefore, an organization such as the APMN is required. Furthermore, international collaboration among Asian countries and countries around the world will be of utmost importance in the future. PMID:25364648

Cho, Sung Yoon; Sohn, Young Bae; Jin, Dong-Kyu

2014-08-01

20

Development of a numerical simulator of human swallowing using a particle method (Part 2. Evaluation of the accuracy of a swallowing simulation using the 3D MPS method).  

Science.gov (United States)

The aim of this study was to develop and evaluate the accuracy of a three-dimensional (3D) numerical simulator of the swallowing action using the 3D moving particle simulation (MPS) method, which can simulate splashes and rapid changes in the free surfaces of food materials. The 3D numerical simulator of the swallowing action using the MPS method was developed based on accurate organ models, which contains forced transformation by elapsed time. The validity of the simulation results were evaluated qualitatively based on comparisons with videofluorography (VF) images. To evaluate the validity of the simulation results quantitatively, the normalized brightness around the vallecula was used as the evaluation parameter. The positions and configurations of the food bolus during each time step were compared in the simulated and VF images. The simulation results corresponded to the VF images during each time step in the visual evaluations, which suggested that the simulation was qualitatively correct. The normalized brightness of the simulated and VF images corresponded exactly at all time steps. This showed that the simulation results, which contained information on changes in the organs and the food bolus, were numerically correct. Based on these results, the accuracy of this simulator was high and it could be used to study the mechanism of disorders that cause dysphasia. This simulator also calculated the shear rate at a specific point and the timing with Newtonian and non-Newtonian fluids. We think that the information provided by this simulator could be useful for development of food products, medicines, and in rehabilitation facilities. PMID:24110356

Kamiya, Tetsu; Toyama, Yoshio; Michiwaki, Yukihiro; Kikuchi, Takahiro

2013-01-01

 
 
 
 
21

On the consistency of MPS  

CERN Document Server

The consistency of Moving Particle Semi-implicit (MPS) method in reproducing the gradient, divergence and Laplacian differential operators is discussed in the present paper. Its relation to the Smoothed Particle Hydrodynamics (SPH) method is rigorously established. The application of the MPS method to solve the Navier-Stokes equations using a fractional step approach is treated, unveiling inconsistency problems when solving the Poisson equation for the pressure. A new corrected MPS method incorporating boundary terms is proposed. Applications to one dimensional boundary value Dirichlet and mixed Neumann-Dirichlet problems and to two-dimensional free-surface flows are presented.

Souto-Iglesias, Antonio; González, Leo M; Cercos-Pita, Jose L

2013-01-01

22

On the consistency of MPS  

Science.gov (United States)

The consistency of the Moving Particle Semi-implicit (MPS) method in reproducing the gradient, divergence and Laplacian differential operators is discussed in the present paper. Its relation to the Smoothed Particle Hydrodynamics (SPH) method is rigorously established. The application of the MPS method to solve the Navier-Stokes equations using a fractional step approach is treated, unveiling inconsistency problems when solving the Poisson equation for the pressure. A new corrected MPS method incorporating boundary terms is proposed. Applications to one dimensional boundary value Dirichlet and mixed Neumann-Dirichlet problems and to two-dimensional free-surface flows are presented.

Souto-Iglesias, Antonio; Macià, Fabricio; González, Leo M.; Cercos-Pita, Jose L.

2013-03-01

23

MPS beam control software architecture  

International Nuclear Information System (INIS)

The new Machine Protection System (MPS) now being tested at SLAC has a beam control subsystem resident in processors located close to the beam monitoring devices within the machine. There are two types of beam control micros: Algorithm Processors (AP's) which collect and evaluate data from monitoring devices, and a Supervisor (SUPE) which collects and evaluates data from all the AP's. The SUPE also receives the global machine beamcode indicating beam presence, and passes it on to the AP's. The SUPE receives the beamcode pattern from the Master Pattern Generator (MPG) via a shared-memory communication link. MIL-1553 serial communication is used between the SUPE and the AP's, and between the AP's and the monitoring devices. Multitasking software is used to allow high priority handling of data evaluation and low priority handling of host/user interfacing and event reporting. Pipelining of data between acquisition and evaluation and reporting is used to accommodate the processing capacity, while still supporting full processing at the 36OHz broadcast rate of the beamcode pattern

24

Director, Division of Chemistry, ES-1301, MPS/CHE (Closes: 11/30/2005)  

Science.gov (United States)

... of Chemistry (CHE), Directorate for Mathematical and Physical Sciences (MPS) LOCATION: Arlington ... REQUIREMENTS EXECUTIVE/MANAGERIAL Essential 1. Leading Change. Demonstrated ability to develop and ...

25

DET/MPS - The GSFC Energy Balance Programs  

Science.gov (United States)

Direct Energy Transfer (DET) and MultiMission Spacecraft Modular Power System (MPS) computer programs perform mathematical modeling and simulation to aid in design and analysis of DET and MPS spacecraft power system performance in order to determine energy balance of subsystem. DET spacecraft power system feeds output of solar photovoltaic array and nickel cadmium batteries directly to spacecraft bus. MPS system, Standard Power Regulator Unit (SPRU) utilized to operate array at array's peak power point. DET and MPS perform minute-by-minute simulation of performance of power system. Results of simulation focus mainly on output of solar array and characteristics of batteries. Both packages limited in terms of orbital mechanics, they have sufficient capability to calculate data on eclipses and performance of arrays for circular or near-circular orbits. DET and MPS written in FORTRAN-77 with some VAX FORTRAN-type extensions. Both available in three versions: GSC-13374, for DEC VAX-series computers running VMS. GSC-13443, for UNIX-based computers. GSC-13444, for Apple Macintosh computers.

Jagielski, J. M.

1994-01-01

26

Microcontroller Programming and Interfacing TI MPS433  

CERN Document Server

This book provides a thorough introduction to the Texas Instruments MPS430 microcontroller. The MPS430 is a 16-bit reduced instruction set (RISC) processor that features ultra low power consumption and integrated digital and analog hardware. Variants of the MPS430 microcontroller have been in production since 1993. This provides for a host of MPS430 products including evaluation boards, compilers, and documentation. A thorough introduction to the MPS430 line of microcontrollers, programming techniques, and interface concepts are provided along with considerable tutorial information with many i

Barrett, Steven

2011-01-01

27

Phosphoregulation of human Mps1 kinase.  

Science.gov (United States)

The dual-specificity protein kinase Mps1 (monopolar spindle 1) is a phosphoprotein required for error-free mitotic progression in eukaryotes. In the present study, we have investigated human Mps1 phosphorylation using combined mass spectrometric, mutational and phosphospecific antibody approaches. We have identified 16 sites of Mps1 autophosphorylation in vitro, several of which are required for catalytic activity after expression in bacteria or in cultured human cells. Using novel phosphospecific antibodies, we show that endogenous Mps1 is phosphorylated on Thr(686) and Ser(821) during mitosis, and demonstrate that phosphorylated Mps1 localizes to the centrosomes of metaphase cells. Taken together, these results reveal the complexity of Mps1 regulation by multi-site phosphorylation, and demonstrate conclusively that phosphorylated Mps1 associates with centrosomes in mitotic human cells. PMID:18680479

Tyler, Rebecca K; Chu, Matthew L H; Johnson, Hannah; McKenzie, Edward A; Gaskell, Simon J; Eyers, Patrick A

2009-01-01

28

Simulation of the incompressible flows with the MPS method  

International Nuclear Information System (INIS)

The moving particle semi-implicit (MPS) method is a fully Lagrangian method developed for the incompressible viscous flow. The Rayleigh-Taylor instability (RTI) between Silicon oil and water driven by the buoyancy force was successfully simulated with the MPS method. The three typical stages of the RTI development are clearly simulated. Bubble and spike shapes are consistent with the prediction for a low Atwood-number RTI. The bubble numbers agree well with the prediction by the linear analysis of RTI. The results are in good agreement with the experimental observation. Then, the natural convection in enclosures had been successfully simulated with the MPS method. The results for the Nusselt numbers are consistent with the benchmark calculation. In the calculation, a new Laplacian model had been presented and verified. (authors)

29

Simulation of Droplet Generation in Micro Flow Using MPS Method  

Science.gov (United States)

Micro droplet generation is one of the basic functions in a micro total analysis system (micro TAS). Micro TAS has a lot of advantages and thus has wide range of applications in these days. In this study, a numerical calculation code for micro multi-phase flow is developed using Moving Particle Semi-implicit (MPS) method. Since surface tension is extremely strong and dominant in micro multi-phase flow, a time step is divided to sub-time steps for the surface tension term. This sub-time step algorithm enables us to calculate micro multi-phase flow efficiently with keeping numerical stability. Micro droplet generation in a micro channel is analyzed by the present code in two dimensions. The calculated droplet size, pitch and production rate show good agreement with those of the experiment.

Harada, Takahiro; Suzuki, Yukihito; Koshizuka, Seiichi; Arakawa, Takahiro; Shoji, Shuichi

30

Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes.  

Science.gov (United States)

The dual-specificity protein kinase monopolar spindle 1 (Mps1) is a central component of the mitotic spindle assembly checkpoint (SAC), a sensing mechanism that prevents anaphase until all chromosomes are bioriented on the metaphase plate. Partial depletion of Mps1 protein levels sensitizes transformed, but not untransformed, human cells to therapeutic doses of the anticancer agent Taxol, making it an attractive novel therapeutic cancer target. We have previously determined the X-ray structure of the catalytic domain of human Mps1 in complex with the anthrapyrazolone kinase inhibitor SP600125. In order to validate distinct inhibitors that target this enzyme and improve our understanding of nucleotide binding site architecture, we now report a biophysical and structural evaluation of the Mps1 catalytic domain in the presence of ATP and the aspecific model kinase inhibitor staurosporine. Collective in silico, enzymatic, and fluorescent screens also identified several new lead quinazoline Mps1 inhibitors, including a low-affinity compound termed Compound 4 (Cpd 4), whose interaction with the Mps1 kinase domain was further characterized by X-ray crystallography. A novel biophysical analysis demonstrated that the intrinsic fluorescence of SP600125 changed markedly upon Mps1 binding, allowing spectrophotometric displacement analysis and determination of dissociation constants for ATP-competitive Mps1 inhibitors. By illuminating the structure of the Mps1 ATP-binding site our results provide novel biophysical insights into Mps1-ligand interactions that will be useful for the development of specific Mps1 inhibitors, including those employing a therapeutically validated quinazoline template. PMID:20099905

Chu, Matthew L H; Lang, Zhaolei; Chavas, Leonard M G; Neres, João; Fedorova, Olga S; Tabernero, Lydia; Cherry, Mike; Williams, David H; Douglas, Kenneth T; Eyers, Patrick A

2010-03-01

31

Enzyme replacement therapy (ERT) procedure for mucopolysaccharidosis type II (MPS II) by intraventricular administration (IVA) in murine MPS II.  

Science.gov (United States)

Mucopolysaccharidosis type II (MPS II), or Hunter syndrome, is a lysosomal storage disorder caused by a deficiency of iduronate-2-sulfatase (IDS) and is characterized by the accumulation of glycosaminoglycans (GAGs). MPS II has been treated by hematopoietic stem cell therapy (HSCT)/enzyme replacement therapy (ERT), but its effectiveness in the central nervous system (CNS) is limited because of poor enzyme uptake across the blood-brain barrier (BBB). To increase the efficacy of ERT in the brain, we tested an intraventricular ERT procedure consisting of repeated administrations of IDS (20 ?g/mouse/3 weeks) in IDS-knockout, MPS II model mice. The IDS enzyme activity and the accumulation of total GAGs were measured in mouse brains. The IDS activity was significantly increased, and the accumulation of total GAGs was decreased in the MPS II mouse brains treated with multiple administrations of IDS via intraventricular ERT. Additionally, a high level of IDS enzyme activity was appreciated in other MPS II mouse tissues, such as the liver, spleen, testis and others. A Y-maze was used to test learning and memory after repeated intraventricular ERT with IDS. The IDS-treated mouse groups recovered the capacity for short-term memory and activity. Although large and small vacuoles were found at the margin of the cerebellar Purkinje cells in the disease-control mice, these vacuoles disappeared upon treated with IDS. Loss of vacuoles was also observed in other tissues (liver, kidney and testis). These results demonstrate the possible efficacy of an ERT procedure with intraventricular administration of IDS for the treatment of MPS II. PMID:22704483

Higuchi, Takashi; Shimizu, Hiromi; Fukuda, Takahiro; Kawagoe, Shiho; Matsumoto, Juri; Shimada, Yohta; Kobayashi, Hiroshi; Ida, Hiroyuki; Ohashi, Toya; Morimoto, Hideto; Hirato, Tohru; Nishino, Katsuya; Eto, Yoshikatsu

2012-09-01

32

Addendum to "On the consistency of MPS"  

CERN Document Server

The analogies between the Moving Particle Semi-implicit method (MPS) and Incompressible Smoothed Particle Hydrodynamics method (ISPH) are established in this note, as an extension of the MPS consistency analysis conducted in "Souto-Iglesias et al., Computer Physics Communications, 184(3), 2013."

Souto-Iglesias, Antonio; González, Leo M; Cercos-Pita, Jose L

2013-01-01

33

Acid mucopolysaccharides (MPS) in fibroblast cultures. 4  

International Nuclear Information System (INIS)

Cultures of embryonic rat fibroblasts were incubated with 35S-sulfate at pH 6.6 and 7.4 (Eagle medium, Hepes buffer) for 48 hours. The MPS were isolated and fractionated. Determination of hexuronic acid was done according to Bitter and Muir, measuring of sulfate incorporation by liquid scintillation counting. It could be demonstrated in which way the MPS pattern was modified in fibroblast cultures by changes in the concentrations of lactate and protons. Individually acting anabolic and catabolic processes that were influenced by cell density, pH and lactate were decisive factors for the MPS pools concerned. (author)

34

MPS simulation of 2-D spontaneous dynamic rupture propagation  

Science.gov (United States)

In order to carry out numerical simulations of seismic motions, it is important to model earthquake faults. Several numerical methods have been developed for simulating spontaneous dynamic rupture on earthquake faults, obeying a certain fracture criterion or friction law. In such simulations, boundary conditions of dislocation are usually set on the fault. Traction-at-split-node (TSN) method (Andrews[1973]) is one of the most popular methods. So far, this method has introduced a boundary condition of dislocation mainly into a finite difference (FD) or a finite element (FE) method. However, the regular grid-based FD method is not so suitable for modeling "curved winding faults". The FE method can treat complex geometry, but it usually takes time to construct fine meshes suitable for keeping numerical accuracy in the complex geometry. Actually, faults in the nature are not always flat and have some complexities in geometry. In order to remedy this disadvantage, we develop a new method which introduces a boundary condition of dislocation into Moving Particle Semi-implicit (MPS) method. The MPS method, which is one of particle methods such as the SPH (Smoothed-Particle Hydrodynamics) method, was newly developed by Koshizuka and his colleagues in 1996 in order to simulate non-compressive fluid. Then, it has been applied for simulating deformation and wave propagation in elastic media since Chikazawa (1999). For instance, Takekawa et al. (2008) carried out simulation of elastic wave propagation and succeeded in simulating Hopkinson's effect. The MPS method is based on Lagrangian formulation and an elastic body is described as an aggregate of particles. The government equations for the elastic medium are interpreted into interactions among these particles. These interactions are equivalent to those of normal and tangential springs. Each particle interacts with its neighboring particles using a local weighting function. Therefore, it is quite easy to deal with heterogeneity and complex geometry. In this respect, MPS is similar to SPH. However, the MPS method applies simplified differential operator models solely based on a local weighted averaging process without taking the gradient of a kernel function, whereas the differential operators are applied to spatially weighting kernels in the SPH method. In this study, we introduced a boundary condition of "2-D curved winding faults" into a MPS method referring to the TSN method. To be specific, we set "fault particles" at both sides of the fault. In these particles, "interaction force" in the MPS method was substituted for "restoring force" in the TNS method. In addition we used a slip-dependent friction law which has a linear slip-weakening friction coefficient with a characteristic slip distance. In the presentation, we show the details of implementation of TSN on the earthquake fault into the MPS method, and discuss the feasibility and the accuracy of the MPS method for a 2-D spontaneous dynamic propagation problem.

Sakamoto, T.; Hirahara, K.

2009-12-01

35

MPS VAX monitor and control software architecture  

International Nuclear Information System (INIS)

The new Machine Protection System (MPS) now being tested at the SLAC Linear Collider (SLC) includes monitoring and controlling facilities integrated into the existing VAX control system. The actual machine protection is performed by VME micros which control the beam repetition rate on a pulse-by-pulse basis based on measurements from fault detectors. The VAX is used to control and configure the VME micros, configure custom CAMAC modules providing the fault detector inputs, monitor and report faults and system errors, update the SLC database, and interface with the user. The design goals of the VAX software include a database-driven system to allow configuration changes without code changes, use of a standard TCP/IP-based message service for communication, use of existing SLCNET micros for CAMAC configuration, security and verification features to prevent unauthorized access, error and alarm logging and display updates as quickly as possible, and use of touch panels and X-windows displays for the user interface

36

Sociological profiles of Mersin MP’s  

Directory of Open Access Journals (Sweden)

Full Text Available This study was designed to find general characteristics of Mersin MP’s in Multi Party Period (Since 1950 up to Date. On the final stage the place of Mersin MP’s in Turkish political elites will be examined. Social background peculiarities (gender, age, education, occupation, family size were used to achieve the objectives. Documentary and historical research techniques were applied in the paper. An original data set was produced for analysis from the official publications and records and publications of the Turkish Grand National Assembly which is the main legislative organ in Turkey. The data set was analysed by using SPSS (Statistical Package for the Social Sciences.As a result of examining all the assemblies in the Multi Party period these major findings were discovered in related with Mersin MP’s: A large majority of Mersin MP’s were well educated, male, married, with a small family size and middle aged. Moreover the large majority of Mersin MP’s were lawyers and civil bureaucrats. Although the situation has begun to change in recent years, the deputies have exhibited an elitist character as compared with the general population of Mersin.

D. Ali Arslan

2012-08-01

37

A simple algorithm to search for all d-MPs with unreliable nodes  

International Nuclear Information System (INIS)

Many real-world systems are multistate systems composed of multistate components in which the reliability can be computed in terms of the lower bound points of level d, by formulating in terms of either the d-minimal paths (d-MPs) or d-minimal cutsets (d-MCs). Such systems (electric power, transportation, etc.) may be regarded as flow networks whose arcs have independent, discrete, limited and multivalued random capacities. A simple method is proposed to search for all d-MPs for network reliability in a system subject to both arc and node failures. The proposed method does not require re-enumeration for all of the d-MPs or MPs for the additional the node failure consideration. Because only the sum of the flow through into (or from) each unreliable node of the d-MPs which found in the network with perfect nodes is calculated, the proposed algorithm is easier to understand and implement. With considering unreliable nodes, this method is also more realistic and valuable for performing the reliability analysis in an existing network. The computational complexity of the proposed algorithm is analyzed and compared with the existing methods. One example is illustrated to show how all d-MPs are generated in a network with arc and node failures solved by the proposed algorithm

38

Development of d.c. power supply for gyrotron with energy recovery system  

International Nuclear Information System (INIS)

A new type of power supply system for a gyrotron with collector potential depression (CPD) to enhance gyrotron efficiency was developed. The power supply system is composed of a main power supply (MPS) and an acceleration power supply (APS). The APS which provides the stable high field to the magnetron injection gun (MIG) of the gyrotron is the key point of the system. The DC-DC converter technique is applied to the APS and it can output 100 kV of maximum voltage within ±0.5% stability and 300 mA of maximum current. The CPD gyrotron operation was successfully achieved with an efficiency of 48% and power of 350 kW for 5 s at 110 GHz. The stable gyrotron operation, without regulation of MPS, which provides the d.c. input power to the gyrotron, has been demonstrated by the combination of the APS and MPS. (orig.)

39

Solution NMR of MPS-1 Reveals a Random Coil Cytosolic Domain Structure  

Science.gov (United States)

Caenorhabditis elegans MPS1 is a single transmembrane helical auxiliary subunit that co-localizes with the voltage-gated potassium channel KVS1 in the nematode nervous system. MPS-1 shares high homology with KCNE (potassium voltage-gated channel subfamily E member) auxiliary subunits, and its cytosolic domain was reported to have a serine/threonine kinase activity that modulates KVS1 channel function via phosphorylation. In this study, NMR spectroscopy indicated that the full length and truncated MPS-1 cytosolic domain (134–256) in the presence or absence of n-dodecylphosphocholine detergent micelles adopted a highly flexible random coil secondary structure. In contrast, protein kinases usually adopt a stable folded conformation in order to implement substrate recognition and phosphoryl transfer. The highly flexible random coil secondary structure suggests that MPS-1 in the free state is unstructured but may require a substrate or binding partner to adopt stable structure required for serine/threonine kinase activity. PMID:25347290

Lai, Chaohua; Li, Juan; Zheng, Yuanyuan; Xiong, Ying; Zhang, Longhua; Tian, Changlin

2014-01-01

40

An improved MPS method for numerical simulations of convective heat transfer problems  

Science.gov (United States)

An improved moving-particle semi-implicit (MPS) method was developed for numerical simulations of convective heat transfer problems. The MPS method, which is based on particles and their interactions, is a fully Lagrangian particle method for incompressible flows. A new Laplacian model and a new method for treating boundary conditions were proposed to solve numerical difficulties resulting from the original MPS method. Results of several numerical tests show the validity of the improved MPS method with the proposed model and method.The application of the present MPS method to Rayleigh-Benard convection phenomena demonstrated the effectiveness of the proposed model and method on the numerical simulation of convective heat transfer problems. The dependence of the Nusselt number on the Rayleigh number was in good agreement with an empirical formula. The temperature contour and velocity distribution also agree well with the simulation results obtained with other methods. The roll pattern developed in the horizontal fluid layer as well as the convective heat transfer was successfully simulated with three-dimensional MPS calculations.

Zhang, Shuai; Morita, Koji; Fukuda, Kenji; Shirakawa, Noriyuki

2006-05-01

 
 
 
 
41

Fully-automated field mapping of a dipole magnet of a multi-passage spectrometer (MPS)  

International Nuclear Information System (INIS)

MLLTRAP is a Penning-trap mass-spectrometer facility, which is currently being commissioned at the Maier-Leibnitz Laboratory in Garching. Here, atomic mass values are determined by measuring cyclotron frequencies of stored ions in a strong magnetic field. In the future, highly-charged ions should be utilized for an improvement in the achievable mass accuracy. For this purpose, singly-charged ions will have to be injected into a charge-breeding device, such as an EBIT, and transferred back towards the Penning traps, while being q/A selected. To fulfill these tasks a multi-passage-spectrometer (MPS) is being built. It consists of a fast-ramping, round-pole dipole magnet with an electrostatic mirror system. A basic requirement for building the MPS is a detailed knowledge on the magnetic field produced by the magnet. It is necessary to simulate the trajectories of the ions and gain knowledge on the design and geometry of the electrostatic mirror system and the vacuum chamber. For this purpose, a robot was designed, which - powered by three step motors - measures the magnetic field fully automated. The robot moves a Hall probe within three dimensions with a resolution of 1 mm and an uncertainty of 0.5 mm. In this presentation, the development of the robot, its control and data acquisition via LabView and the results are presented.

42

Fully-automated field mapping of a dipole magnet of a multi-passage spectrometer (MPS)  

Energy Technology Data Exchange (ETDEWEB)

MLLTRAP is a Penning-trap mass-spectrometer facility, which is currently being commissioned at the Maier-Leibnitz Laboratory in Garching. Here, atomic mass values are determined by measuring cyclotron frequencies of stored ions in a strong magnetic field. In the future, highly-charged ions should be utilized for an improvement in the achievable mass accuracy. For this purpose, singly-charged ions will have to be injected into a charge-breeding device, such as an EBIT, and transferred back towards the Penning traps, while being q/A selected. To fulfill these tasks a multi-passage-spectrometer (MPS) is being built. It consists of a fast-ramping, round-pole dipole magnet with an electrostatic mirror system. A basic requirement for building the MPS is a detailed knowledge on the magnetic field produced by the magnet. It is necessary to simulate the trajectories of the ions and gain knowledge on the design and geometry of the electrostatic mirror system and the vacuum chamber. For this purpose, a robot was designed, which - powered by three step motors - measures the magnetic field fully automated. The robot moves a Hall probe within three dimensions with a resolution of 1 mm and an uncertainty of 0.5 mm. In this presentation, the development of the robot, its control and data acquisition via LabView and the results are presented.

Meissner, Robert; Thirolf, Peter; Weber, Christine [Fakultaet fuer Physik, LMU - Muenchen (Germany)

2013-07-01

43

Develop and Evaluate the Effects of Multimodal Presentation System on Elementary ESL Students  

Science.gov (United States)

The purpose of this study is to develop and evaluate the effects of multimodal presentation system (MPS), a multimodal presentation software integrated with interactive whiteboard (IWB), on student learning in the elementary English as second language (ESL) course. It focuses primarily on techniques and tools to enhance the students' ESL…

Kuo, Fang-O; Yu, Pao-Ta; Hsiao, Wei-Hung

2013-01-01

44

BNL multiparticle spectrometer (MPS) program  

International Nuclear Information System (INIS)

The design and operation of the BNL multiparticle spectrometer are described. Also a formation experiment anti pp ? n/sub c/ ? final state was studied at 3.7 to 4.2 GeV/c tuning the total cm energy of the anti pp system to lie near the just below the J mass to search for the existence of a narrow peak (J/sup PC/ = O/sup -+ /GAMMA? several MeV). No outstanding peak is seen, but an approximate cross section limit is given in the region of a few microbarns. There is a clear K0 signal. Also a plot of the effective mass and missing mass for events with two neutral K's produced by 8.7-GeV/c ?- on hydrogen is given

45

The SUN protein Mps3 controls Ndc1 distribution and function on the nuclear membrane.  

Science.gov (United States)

In closed mitotic systems such as Saccharomyces cerevisiae, nuclear pore complexes (NPCs) and the spindle pole body (SPB) must assemble into an intact nuclear envelope (NE). Ndc1 is a highly conserved integral membrane protein involved in insertion of both complexes. In this study, we show that Ndc1 interacts with the SUN domain-containing protein Mps3 on the NE in live yeast cells using fluorescence cross-correlation spectroscopy. Genetic and molecular analysis of a series of new ndc1 alleles allowed us to understand the role of Ndc1-Mps3 binding at the NE. We show that the ndc1-L562S allele is unable to associate specifically with Mps3 and find that this mutant is lethal due to a defect in SPB duplication. Unlike other ndc1 alleles, the growth and Mps3 binding defect of ndc1-L562S is fully suppressed by deletion of POM152, which encodes a NPC component. Based on our data we propose that the Ndc1-Mps3 interaction is important for controlling the distribution of Ndc1 between the NPC and SPB. PMID:24515347

Chen, Jingjing; Smoyer, Christine J; Slaughter, Brian D; Unruh, Jay R; Jaspersen, Sue L

2014-02-17

46

Capturing phenotypic heterogeneity in MPS I: results of an international consensus procedure  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Mucopolysaccharidosis type I (MPS I is traditionally divided into three phenotypes: the severe Hurler (MPS I-H phenotype, the intermediate Hurler-Scheie (MPS I-H/S phenotype and the attenuated Scheie (MPS I-S phenotype. However, there are no clear criteria for delineating the different phenotypes. Because decisions about optimal treatment (enzyme replacement therapy or hematopoietic stem cell transplantation need to be made quickly and depend on the presumed phenotype, an assessment of phenotypic severity should be performed soon after diagnosis. Therefore, a numerical severity scale for classifying different MPS I phenotypes at diagnosis based on clinical signs and symptoms was developed. Methods A consensus procedure based on a combined modified Delphi method and a nominal group technique was undertaken. It consisted of two written rounds and a face-to-face meeting. Sixteen MPS I experts participated in the process. The main goal was to identify the most important indicators of phenotypic severity and include these in a numerical severity scale. The correlation between the median subjective expert MPS I rating and the scores derived from this severity scale was used as an indicator of validity. Results Full consensus was reached on six key clinical items for assessing severity: age of onset of signs and symptoms, developmental delay, joint stiffness/arthropathy/contractures, kyphosis, cardiomyopathy and large head/frontal bossing. Due to the remarkably large variability in the expert MPS I assessments, however, a reliable numerical scale could not be constructed. Because of this variability, such a scale would always result in patients whose calculated severity score differed unacceptably from the median expert severity score, which was considered to be the 'gold standard'. Conclusions Although consensus was reached on the six key items for assessing phenotypic severity in MPS I, expert opinion on phenotypic severity at diagnosis proved to be highly variable. This subjectivity emphasizes the need for validated biomarkers and improved genotype-phenotype correlations that can be incorporated into phenotypic severity assessments at diagnosis.

de Ru Minke H

2012-04-01

47

Development of fast beam-stop system using RF chopper  

International Nuclear Information System (INIS)

To avoid heat damage and radioactivation by beam loss of the J-PARC accelerator, Machine Protection System (MPS) has been developed. Actually, high responsibility and high reliability have been achieved in J-PARC. Beam-stop method in addition to a way of RFQ OFF has been requested in order to avoid damage to the RFQ. Therefore, we have been developing a fast beam-stop system by using a RF chopper. The fast beam-stop system, including beam test, is described in this paper. (author)

48

The viStaMPS tool for visualization and manipulation of time series interferometric results  

Science.gov (United States)

In the last decade, Synthetic Aperture Radar Interferometry (InSAR) has become operational as a technique that allows remote detection of deformation at the Earth's surface. Analysis of time series of SAR images extends the area where InSAR can be successfully applied and also permits detection of smaller displacements through the reduction of error sources. Stanford Method for Persistent Scatterers (StaMPS) InSAR implementation, which is based on the processing of multi-temporal SAR data, is widely used for ground deformation monitoring. This is due mainly to its proven reliability and freeware distribution among the scientific community. However, some issues can make the interpretation of the results a difficult task: StaMPS supports data processing based on command prompt, which increases the difficulty of usage by users not familiar with the specific programming language that supports StaMPS. Moreover, several visualization tasks are not implemented in the standard approach requiring that each user develop its own code for visualization and interpretation purposes. In this paper, we present viStaMPS, a new visual application developed to enhance the visualization, manipulation and exportation of StaMPS results. The programmed application is developed in Matlab through the Graphical User Interface (GUI) and no coding is required for running it, which avoids any programming language knowledge for standard uses. The included graphical interface is very versatile allowing the user to choose among several features: visualization, manipulation and exportation of data which are not available in the original StaMPS.

Sousa, Joaquim J.; Magalhães, Luis G.; Ruiz, Antonio M.; Sousa, António M. R.; Cardoso, Gil

2013-03-01

49

Numerical analysis of fuel-coolant interactions in coolant injection mode using MPS  

International Nuclear Information System (INIS)

The numerical method used in this study is the Moving Particle Semi-implicit (MPS) method which is based on moving particles and their interactions. Grids are not necessary, so that large fluid deformation can be calculated without numerical diffusion. Boiling and solidification models are developed for the MPS method. Melt injection is calculated considering boiling and solidification. Clusters of melt particles appear due to solidification. To understand the fundamental physics of the jet penetration, water jet injection into a pool of a denser fluid under non-boiling and isothermal conditions are calculated using the MPS method. The density ratio of the denser fluid to water is 1.88 (fluorinert) or 9.4 (anatomical alloy). The calculation results are compared with experiments, which were conducted in the ALPHA/MUSE facility at JAERI. In the calculation, air entrainment is observed as the experiments due to the jet penetration. However, the maximum jet penetration depth is shallower than the experiments. (author)

50

Email and political campaigning: the experience of MPs in Westminster  

Directory of Open Access Journals (Sweden)

Full Text Available Traditionally individual politicians communicated directly with their constituents, but the arrival of the mass media, especially television, eroded the role of direct communication. The development of new Information Communication Technologies (ICTs is now re-opening the use of direct communication as part of post-modern campaigning (Norris 2000, with the Internet providing an alternative to media relations. The World Wide Web has attracted great interest from political commentators, but so far email has been largely ignored. Yet the Web is a pull technique, whereas the push nature of email opens up new campaigning possibilities. Downes and Mui (2000 suggest that email represents potentially a 'killer app' which might revolutionize the way MPs approach re-election. A survey of Members of Parliament (MPs Assembly Members (AMs of the Welsh Assembly and Members of the Scottish Parliament (MSPs examines whether they have grasped the opportunities email represents. The research suggests that the outbound use of email for campaigning purposes is limited to a small number of pioneers. Resources, parliamentary culture and party affiliation all shape the use of email campaigning.

Nigel Jackson

2004-04-01

51

RoMPS concept review automatic control of space robot, volume 2  

Science.gov (United States)

Topics related to robot operated materials processing in space (RoMPS) are presented in view graph form and include: (1) system concept; (2) Hitchhiker Interface Requirements; (3) robot axis control concepts; (4) Autonomous Experiment Management System; (5) Zymate Robot Controller; (6) Southwest SC-4 Computer; (7) oven control housekeeping data; and (8) power distribution.

Dobbs, M. E.

1991-01-01

52

Analytical model for reverse characteristics of 4H–SiC merged PN–Schottky (MPS) diodes  

International Nuclear Information System (INIS)

A new analytical model for reverse characteristics of 4H–SiC merged PN–Schottky diodes (MPS or JBS) is developed. To accurately calculate the reverse characteristics of the 4H–SiC MPS diode, the relationship between the electric field at the Schottky contact and the reverse bias is analytically established by solving the cylindrical Poisson equation after the channel has pinched off. The reverse current density calculated from the Wentzel–Kramers–Brillouin (WKB) theory is verified by comparing it with the experimental result, showing that they are in good agreement with each other. Moreover, the effects of P-region spacing (S) and P-junction depth (Xj) on the characteristics of 4H–SiC MPS are analysed, and are particularly useful for optimizing the design of the high voltage MPS diodes. (condensed matter: electronic structure, electrical, magnetic, and optical properties)

53

Numerical analysis for hydrodynamic motions of floating structure using MPS method  

Science.gov (United States)

The authors started this research on estimation method of responses for floating structures using Computational Fluid Dynamics (CFD). This paper is first step, which has potential to be very valuable to the engineering community. The numerical method used in this study is the Moving Particle Semi-implicit (MPS) method 1) 2), which is based on particles and their interactions. MPS method that was developed recently is one of panicle method. The particle number density is implicitly required to be constant to satisfy incompressibility. A semi-implicit algorithm is used to for two dimensional incompressible non-viscous flow analysis. The particles whose particle number densities are below a set point are considered as on the free surface. In this paper, first, the authors explain the outline of MPS method that Kshizuka et al. developed. You can see more details of this method by references. And the calculation test of column collapse problem is carried out to check our code that we developed. Second, the modeling of free surfaces is explained. And the authors proposed the way to skip irregular data of wave height. Validation of wave profiles was carried out comparing Stokes theory. Third, calculation results of floating body are showed. This method of calculating response of floating structure is by Koshizuka et al. 3). Finally, the authors show calculation results of wave exciting forces by MPS method comparing singular point distribution method (SDM).

Maeda, H.; Asanuma, T.; Nishimoto, K.; Tsukamoto, M. M.; Masuda, K.; Ikoma, T.

2004-06-01

54

Characterization of novel MPS1 inhibitors with preclinical anticancer activity.  

Science.gov (United States)

Monopolar spindle 1 (MPS1), a mitotic kinase that is overexpressed in several human cancers, contributes to the alignment of chromosomes to the metaphase plate as well as to the execution of the spindle assembly checkpoint (SAC). Here, we report the identification and functional characterization of three novel inhibitors of MPS1 of two independent structural classes, N-(4-{2-[(2-cyanophenyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}phenyl)-2-phenylacetamide (Mps-BAY1) (a triazolopyridine), N-cyclopropyl-4-{8-[(2-methylpropyl)amino]-6-(quinolin-5-yl)imidazo[1,2-a]pyrazin-3-yl}benzamide (Mps-BAY2a) and N-cyclopropyl-4-{8-(isobutylamino)imidazo[1,2-a]pyrazin-3-yl}benzamide (Mps-BAY2b) (two imidazopyrazines). By selectively inactivating MPS1, these small inhibitors can arrest the proliferation of cancer cells, causing their polyploidization and/or their demise. Cancer cells treated with Mps-BAY1 or Mps-BAY2a manifested multiple signs of mitotic perturbation including inefficient chromosomal congression during metaphase, unscheduled SAC inactivation and severe anaphase defects. Videomicroscopic cell fate profiling of histone 2B-green fluorescent protein-expressing cells revealed the capacity of MPS1 inhibitors to subvert the correct timing of mitosis as they induce a premature anaphase entry in the context of misaligned metaphase plates. Hence, in the presence of MPS1 inhibitors, cells either divided in a bipolar (but often asymmetric) manner or entered one or more rounds of abortive mitoses, generating gross aneuploidy and polyploidy, respectively. In both cases, cells ultimately succumbed to the mitotic catastrophe-induced activation of the mitochondrial pathway of apoptosis. Of note, low doses of MPS1 inhibitors and paclitaxel (a microtubular poison) synergized at increasing the frequency of chromosome misalignments and missegregations in the context of SAC inactivation. This resulted in massive polyploidization followed by the activation of mitotic catastrophe. A synergistic interaction between paclitaxel and MPS1 inhibitors could also be demonstrated in vivo, as the combination of these agents efficiently reduced the growth of tumor xenografts and exerted superior antineoplastic effects compared with either compound employed alone. Altogether, these results suggest that MPS1 inhibitors may exert robust anticancer activity, either as standalone therapeutic interventions or combined with microtubule-targeting chemicals. PMID:23933817

Jemaà, M; Galluzzi, L; Kepp, O; Senovilla, L; Brands, M; Boemer, U; Koppitz, M; Lienau, P; Prechtl, S; Schulze, V; Siemeister, G; Wengner, A M; Mumberg, D; Ziegelbauer, K; Abrieu, A; Castedo, M; Vitale, I; Kroemer, G

2013-11-01

55

Structural and mechanistic insights into Mps1 kinase activation  

Energy Technology Data Exchange (ETDEWEB)

Mps1 is one of the several essential kinases whose activation is required for robust mitotic spindle checkpoint signalling. The activity of Mps1 is tightly regulated and increases dramatically during mitosis or in response to spindle damage. To understand the molecular mechanism underlying Mps1 regulation, we determined the crystal structure of the kinase domain of Mps1. The 2.7-{angstrom}-resolution crystal structure shows that the Mps1 kinase domain adopts a unique inactive conformation. Intramolecular interactions between the key Glu residue in the {alpha}C helix of the N-terminal lobe and the backbone amides in the catalytic loop lock the kinase in the inactive conformation. Autophosphorylation appears to be a priming event for kinase activation. We identified Mps1 autophosphorylation sites in the activation and the P+1 loops. Whereas activation loop autophosphorylation enhances kinase activity, autophosphorylation at the P+1 loop (T686) is associated with the active kinase. Mutation of T686 autophosphorylation site impairs both autophosphorylation and transphosphorylation. Furthermore, we demonstrated that phosphorylation of T676 may be a priming event for phosphorylation at T686. Finally, we identified two critical lysine residues in the loop between helices {alpha}EF and {alpha}F that are essential for substrate recruitment and maintaining high levels of kinase activity. Our studies reveal critical biochemical mechanisms for Mps1 kinase regulation.

Wang, Wei; Yang, Yuting; Gao, Yuefeng; Xu, Quanbin; Wang, Feng; Zhu, Songcheng; Old, William; Resing, Katheryn; Ahn, Natalie; Lei, Ming; Liu, Xuedong; (Michigan); (Colorado)

2010-11-05

56

MPS controller and diagnostic interface for LINAC  

International Nuclear Information System (INIS)

A micro-controller based control and diagnostic system has been developed to interface DANFYSIK magnet power supplies. A serial communication is employed to control and monitor the status of the magnets and the power supplies. Multiple magnets are connected to a single control unit having key pad and LCD display for stand-alone operation. All diagnostic display and annunciations are implemented. Feature of PC connectivity has further enhanced the flexibility of operation. (author)

57

BASIC STUDY ON FAILURE ANALYSIS WITH USING MPS METHOD  

Science.gov (United States)

MPS method (Moving Particle Semi-implicit or Simulation) is expected as an earthquake response calculation method which can deal with overall responses from elastic wave propagation to failure phenomenon consistently. MPS method solves a wave equation numerically with using particles. Its formulation is very close to that of DEM (Descrete Element Method). It is known that the initial particle configulation affects the failure behavior when DEM is used. Because the influence by the initial configulation is similiarly recognized in MPS analysis, a method which constructs a random initial model is proposed. A formulation for shear and tensile failure, and new contact of particles due to large deformation is also proposed. Failure or collapse analyses caused by fall, own weight or compressive force are conducted. The proposed method is examined through these numerical simulations.

Yoshida, Ikumasa

58

Expert recommendations for the laboratory diagnosis of MPS VI.  

Science.gov (United States)

Mucopolysaccharidosis VI (MPS VI) is a lysosomal storage disease caused by a deficiency of N-acetylgalactosamine 4-sulfatase (arylsulfatase B, ASB). This enzyme is required for the degradation of dermatan sulfate. In its absence, dermatan sulfate accumulates in cells and is excreted in large quantities in urine. Specific therapeutic intervention is available; however, accurate and timely diagnosis is crucial for maximal benefit. To better understand the current practices for diagnosis and to establish diagnostic guidelines, an international MPS VI laboratory diagnostics scientific summit was held in February of 2011 in Miami, Florida. The various steps in the diagnosis of MPS VI were discussed including urinary glycosaminoglycan (uGAG) analysis, enzyme activity analysis, and molecular analysis. The following conclusions were reached. Dilute urine samples pose a significant problem for uGAG analysis and MPS VI patients can be missed by quantitative uGAG testing alone as dermatan sulfate may not always be excreted in large quantities. Enzyme activity analysis is universally acknowledged as a key component of diagnosis; however, several caveats must be considered and the appropriate use of reference enzymes is essential. Molecular analysis supports enzyme activity test results and is essential for carrier testing, subsequent genetic counseling, and prenatal testing. Overall the expert panel recommends caution in the use of uGAG screening alone to rule out or confirm the diagnosis of MPS VI and acknowledges enzyme activity analysis as a critical component of diagnosis. Measurement of another sulfatase enzyme to exclude multiple sulfatase deficiency was recommended prior to the initiation of therapy. When feasible, the use of molecular testing as part of the diagnosis is encouraged. A diagnostic algorithm for MPS VI is provided. PMID:22405600

Wood, T; Bodamer, O A; Burin, M G; D'Almeida, V; Fietz, M; Giugliani, R; Hawley, S M; Hendriksz, C J; Hwu, W L; Ketteridge, D; Lukacs, Z; Mendelsohn, N J; Miller, N; Pasquali, M; Schenone, A; Schoonderwoerd, K; Winchester, B; Harmatz, P

2012-05-01

59

VALIDATION OF THE STATIC PRESSURE AND WAVE PRESSURE BY MPS WITH NEW GRADIENT OPERATOR  

Science.gov (United States)

Accuracy of a highly precised Moving-particle semi-implicit (MPS) method, proposed by the authors, is compared with that of the traditional MPS method on the static fluid pressure and water wave propagation. The MPS method is modified with a precise estimation of the gradient. In a static fluid analysis, a good accuracy is obtained in the modified MPS for static pressure than in the original MPS. In case of progressive water wave propagation analysis, the oscillation of wave pressure can also be simulated with high accuracy. The study suggests that the proposed method for the gradient operator can contribute to improve the accuracy of the MPS method.

Itori, Seiya; Iribe, Tsunakiyo; Nakaza, Eizo

60

Numerical computation of thermally controlled steam bubble condensation using Moving Particle Semi-implicit (MPS) method  

Energy Technology Data Exchange (ETDEWEB)

In the present study, single steam bubble condensation behaviors in subcooled water have been simulated using Moving Particle Semi-implicit (MPS) method. The liquid phase was modeled using moving particles and the two phase interface was set to be a movable boundary which can be tracked by the topological position of the interfacial particles. The interfacial heat transfer was determined according to the heat conduction through the interfacial liquid layer and the coupling between momentum and energy was specially treated. Computational results showed that the bubble experiences various deformations at lower degrees of liquid subcooling while it remains nearly spherical at higher degrees of liquid subcooling. The bubble lifetime is nearly proportional to bubble size and is prolonged at higher system pressures. Bubble lifetime obtained from the MPS method agrees well with the experiments of Kamei and Hirata (1986, 1987), however it is lower than the predictions of Sudhoff et al. (1982). The underestimation is caused by severe bubble deformation at lower degrees of subcooling. The present study exhibits some fundamental characteristics of single steam bubble condensation and is expected to be instructive for further applications of the MPS method to evaluate more complicated bubble dynamics problems.

Tian Wenxi, E-mail: wxtian@mail.xjtu.edu.c [Department of Nuclear Engineering and Management, University of Tokyo, Tokyo 113-8586 (Japan); Department of Nuclear Science and Technology, Xi' an Jiaotong University, Xi' an, Shaanxi 710049 (China); Ishiwatari, Yuki; Ikejiri, Satoshi; Yamakawa, Masanori; Oka, Yoshiaki [Department of Nuclear Engineering and Management, University of Tokyo, Tokyo 113-8586 (Japan)

2010-01-15

 
 
 
 
61

Numerical computation of thermally controlled steam bubble condensation using Moving Particle Semi-implicit (MPS) method  

International Nuclear Information System (INIS)

In the present study, single steam bubble condensation behaviors in subcooled water have been simulated using Moving Particle Semi-implicit (MPS) method. The liquid phase was modeled using moving particles and the two phase interface was set to be a movable boundary which can be tracked by the topological position of the interfacial particles. The interfacial heat transfer was determined according to the heat conduction through the interfacial liquid layer and the coupling between momentum and energy was specially treated. Computational results showed that the bubble experiences various deformations at lower degrees of liquid subcooling while it remains nearly spherical at higher degrees of liquid subcooling. The bubble lifetime is nearly proportional to bubble size and is prolonged at higher system pressures. Bubble lifetime obtained from the MPS method agrees well with the experiments of Kamei and Hirata (1986, 1987), however it is lower than the predictions of Sudhoff et al. (1982). The underestimation is caused by severe bubble deformation at lower degrees of subcooling. The present study exhibits some fundamental characteristics of single steam bubble condensation and is expected to be instructive for further applications of the MPS method to evaluate more complicated bubble dynamics problems.

62

Numerical analysis of film boiling of water at atmospheric pressure using MPS-MAFL method  

International Nuclear Information System (INIS)

Film boiling is avoided to occur in the normal operation of nuclear power plant but it is expected that the film boiling will occur in reactor core and it play important role in post-accident core cooling. Numerical simulation on the development of the steam-water interface and heat transfer in the film boiling of water is performed using Moving Particle Semi-implicit with Meshless Advection using Flow-directional Local-grid(MPS-MAFL) method. The shape change of vapor film and the velocity distribution are coincident with those of experiments. The heat fluxes are compared with those of Berenson's equation for several cases of heater wall temperatures. The heat flux of MPS-MAFL calculation is somewhat lower than that of Berenson's analysis. The reason is because that the distance between computing points is too large for the calculation of heat transfer in a very thin thermal boundary layer and the film thickness is larger than that of real case. From these results, it becomes certain that the heat transfer is mainly affected by the thickness of vapor film and the wall superheat and the MPS-MAFL method is applicable to the film boiling where the phase interface is changed rapidly and complicatedly and the density ratio between the liquid and vapor phases is large

63

Addendum to "On the consistency of MPS" [Comput. Phys. Comm. 184 (3) (2013) 732-745  

Science.gov (United States)

The analogies between the Moving Particle Semi-implicit method (MPS) and Incompressible Smoothed Particle Hydrodynamics method (ISPH) are established in this note, as an extension of the MPS consistency analysis conducted in Souto-Iglesias et al. (2013).

Souto-Iglesias, Antonio; Macià, Fabricio; González, Leo M.; Cercos-Pita, Jose L.

2014-02-01

64

Who Decides Higher Education Policy? MPS, VCS, STEM and HASS  

Science.gov (United States)

In the UK, and in many other countries, policy makers and funding bodies emphasise the importance of the STEM disciplines (science, technology, engineering and mathematics), as opposed to the HASS disciplines (humanities, arts and social sciences), in higher education. Yet an examination of the biographies of UK members of parliament (MPs)…

Tight, Malcolm

2012-01-01

65

Enhancement of performance and stability of MPS mesh-free particle method for multiphase flows characterized by high density ratios  

Science.gov (United States)

The paper presents an enhanced stabilized MPS (Moving Particle Semi-implicit) method for simulation of multiphase flows characterized by high density ratios. The developed method benefits from four previously developed schemes [1] as well as a novel one proposed for accurate, consistent modeling of density at the phase interface. The new scheme can be considered as an extended version of a commonly applied density smoothening scheme and is shown to keep the sharpness of spatial density variations while enhancing the stability and performance of simulations. Further, the paper highlights the importance of applying a Taylor series consistent scheme for calculation of pressure gradient in multiphase MPS-based simulations. By presenting a simple perturbation analysis, it is shown that some commonly applied MPS-based pressure gradient models are prone to increase the level of unphysical perturbations at the phase interface leading to numerical instabilities. The original MPS gradient model with a Gradient Correction [1] is shown to provide stable and accurate results even in case of violent multiphase flows characterized by high density ratios.

Khayyer, Abbas; Gotoh, Hitoshi

2013-06-01

66

Numerical simulation on bubble growth and departure by MPS  

International Nuclear Information System (INIS)

In the present study, a two-dimensional numerical simulation of single bubble growth and departure during nucleate flow boiling was performed on the horizontal, 45 degree inclined and vertical surfaces, respectively, using the moving particle semi-implicit (MPS) method. The numerical results are provided for bubble shape and growth rate, which show a good agreement with the data from the experiment. Bubble sliding motion prior to liftoff as observed in experiments was well predicted from numerical simulation. (authors)

67

British MPs want food law to better protect consumers | EurActiv  

...British MPs want food law to better protect consumers | EurActiv specialreport-vulnerable-consumers,uk-in-europe,health,food health claims,food labelling EU news & ...Network Sign up to our newsletters »Monday 24 February 2014 BROWSE ALL SECTIONS Agriculture & Food Section homepage CAP 2014-2020: A long road to reform Intensive ... Food, drinks and the environment [Archived] Development Policy EU Elections 2014 Section homepage European elections 2014: Different this time?...regulation: The EU's agenda Free movement of labour in the EU 27 Global food prices and CAP reform [Archived] Energy Section homepage Who ...

68

TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers.  

Science.gov (United States)

Breast cancers (BC) carry a complex set of gene mutations that can influence their gene expression and clinical behavior. We aimed to identify genes driven by the TP53 mutation status and assess their clinical relevance in estrogen receptor (ER)-positive and ER-negative BC, and their potential as targets for patients with TP53 mutated tumors. Separate ROC analyses of each gene expression according to TP53 mutation status were performed. The prognostic value of genes with the highest AUC were assessed in a large dataset of untreated, and neoadjuvant chemotherapy treated patients. The mitotic checkpoint gene MPS1 was the most significant gene correlated with TP53 status, and the most significant prognostic marker in all ER-positive BC datasets. MPS1 retained its prognostic value independently from the type of treatment administered. The biological functions of MPS1 were investigated in different BC cell lines. We also assessed the effects of a potent small molecule inhibitor of MPS1, SP600125, alone and in combination with chemotherapy. Consistent with the gene expression profiling and siRNA assays, the inhibition of MPS1 by SP600125 led to a reduction in cell viability and a significant increase in cell death, selectively in TP53-mutated BC cells. Furthermore, the chemical inhibition of MPS1 sensitized BC cells to conventional chemotherapy, particularly taxanes. Our results collectively demonstrate that TP53-correlated kinase MPS1, is a potential therapeutic target in BC patients with TP53 mutated tumors, and that SP600125 warrant further development in future clinical trials. PMID:24462521

Gy?rffy, Balázs; Bottai, Giulia; Lehmann-Che, Jacqueline; Kéri, György; Orfi, László; Iwamoto, Takayuki; Desmedt, Christine; Bianchini, Giampaolo; Turner, Nicholas C; de Thè, Hugues; André, Fabrice; Sotiriou, Christos; Hortobagyi, Gabriel N; Di Leo, Angelo; Pusztai, Lajos; Santarpia, Libero

2014-05-01

69

Operation of the Brookhaven MPS II Facility  

International Nuclear Information System (INIS)

The BNL Multiparticle Spectrometer has recently been equipped with a set of narrow cell drift chambers employing a novel, compact, inexpensive, readout scheme. This has given an order of magnitude improvement in beam rate as well as better spatial resolution. Two experiments have been completed in the first year of operation, a good test of the system. This type of a drift chamber arrangement is ideal for use at high luminosity hadron colliders

70

Coupled Simulation of Seismic Wave Propagation and Failure Phenomena by Use of an MPS Method  

Science.gov (United States)

The failure of brittle materials, for example glasses and rock masses, is commonly observed to be discontinuous. It is, however, difficult to simulate these phenomena by use of conventional numerical simulation methods, for example the finite difference method or the finite element method, because of the presence of computational grids or elements artificially introduced before the simulation. It is, therefore, important for research on such discontinuous failures in science and engineering to analyze the phenomena seamlessly. This study deals with the coupled simulation of elastic wave propagation and failure phenomena by use of a moving particle semi-implicit (MPS) method. It is simple to model the objects of analysis because no grid or lattice structure is necessary. In addition, lack of a grid or lattice structure makes it simple to simulate large deformations and failure phenomena at the same time. We first compare analytical and MPS solutions by use of Lamb's problem with different offset distances, material properties, and source frequencies. Our results show that analytical and numerical seismograms are in good agreement with each other for 20 particles in a minimum wavelength. Finally, we focus our attention on the Hopkinson effect as an example of failure induced by elastic wave propagation. In the application of the MPS, the algorithm is basically the same as in the previous calculation except for the introduction of a failure criterion. The failure criterion applied in this study is that particle connectivity must be disconnected when the distance between the particles exceeds a failure threshold. We applied the developed algorithm to a suspended specimen that was modeled as a long bar consisting of thousands of particles. A compressional wave in the bar is generated by an abrupt pressure change on one edge. The compressional wave propagates along the interior of the specimen and is visualized clearly. At the other end of the bar, the spalling of the bar is reproduced numerically, and a broken piece of the bar is formed and falls away from the main body of the bar. Consequently, these results show that the MPS method effectively reproduces wave propagation and failure phenomena at the same time.

Takekawa, Junichi; Mikada, Hitoshi; Goto, Tada-nori; Sanada, Yoshinori; Ashida, Yuzuru

2013-04-01

71

Numerical analysis of molten core-concrete interaction using MPS method  

International Nuclear Information System (INIS)

Moving particle semi-implicit (MPS) method uses particles for discretization of fluids. Governing equations are transformed to particle interactions. Grids are not necessary. This enables us to analyze multi-fluid and multi-phase flows with large deformation of interfaces. In the present study, a two-dimensional code is developed for molten core-concrete interaction (MCCI) based on the MPS method. Heat transfer is calculated without any specific correlations. Solid is simply represented by fixed particles. A particle can be changed to a moving (fluid) or fixed (solid) particle corresponding to its enthalpy. The developed code is applied to SWISS-2 experiment. The calculation geometry is x-y two dimensions though the experiment was r-z two dimensions. Nucleate boiling and radiation heat transfers are considered between the melt and the water pool. Only heat conduction is assumed among the melt pool, concrete and MgO (side wills). Natural convection in the melt pool is considered using Boussinesq's approximation. Gas release and volume contraction accompanied by the concrete ablation are ignored. Calculated heat flux to the water pool agrees well with the experiment, though the ablation speed in the concrete is a little slower. A stable crust is formed in a short time after water is poured in and the heat flux to the water pool rapidly decreases. The shape of the crust is like a bridge due to the natural convection in the melt p

72

Exploring phase transitions by finite-entanglement scaling of MPS in the 1D ANNNI model  

CERN Document Server

We use the finite-entanglement scaling of infinite matrix product states (iMPS) to explore supposedly infinite order transitions. This universal method may have lower computational costs than finite-size scaling. To this end, we study possible MPS-based algorithms to find the ground states of the transverse axial next-nearest-neighbor Ising (ANNNI) model in a spin chain with first and second neighbor interactions and frustration. The ground state has four distinct phases with transitions of second order and one of supposedly infinite order, the Kosterlitz-Thouless transition. To explore phase transitions in the model, we study general quantities such as the correlation length, entanglement entropy and the second derivative of the energy with respect to the external field, and test the finite-entanglement scaling. We propose a scaling ansatz for the correlation length of a non-critical system in order to explore infinite order transitions. This method provides considerably less computational costs compared to ...

Nagy, Adam

2011-01-01

73

Dynamic wall-shear stress measurements in turbulent pipe flow using the micro-pillar sensor MPS3  

International Nuclear Information System (INIS)

The micro-pillar wall-shear stress sensor MPS3 has been used to measure the dynamic wall-shear stress in turbulent pipe flow. The sensor device consists of a flexible micro-pillar which extends from the wall into the viscous sublayer. The pillar-tip deflection caused by the exerting fluid forces serves as a measure for the local wall-shear stress. The pillar is statically calibrated in linear shear flow. A second-order estimate of the pillar dynamic response based on experimentally determined sensor characteristics shows the potential of the present sensor configuration to also measure the dynamic wall-shear stress. The quality of the micro-pillar shear stress sensor MPS3 to correctly determine the skin friction will be shown by measuring the wall friction in a well-defined fully developed turbulent pipe flow at Reynolds numbers Reb based on the bulk velocity Ub and the pipe diameter D in the range of Reb=10,000-20,000. The results demonstrate a convincing agreement of the mean and dynamic wall-shear stress obtained with the MPS3 sensor technique with analytical, experimental, and numerical results from the literature

74

Centriole assembly and the role of Mps1: defensible or dispensable?  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract The Mps1 protein kinase is an intriguing and controversial player in centriole assembly. Originally shown to control duplication of the budding yeast spindle pole body, Mps1 is present in eukaryotes from yeast to humans, the nematode C. elegans being a notable exception, and has also been shown to regulate the spindle checkpoint and an increasing number of cellular functions relating to genomic stability. While its function in the spindle checkpoint appears to be both universally conserved and essential in most organisms, conservation of its originally described function in spindle pole duplication has proven controversial, and it is less clear whether Mps1 is essential for centrosome duplication outside of budding yeast. Recent studies of Mps1 have identified at least two distinct functions for Mps1 in centriole assembly, while simultaneously supporting the notion that Mps1 is dispensable for the process. However, the fact that at least one centrosomal substrate of Mps1 is conserved from yeast to humans down to the phosphorylation site, combined with evidence demonstrating the exquisite control exerted over centrosomal Mps1 levels suggest that the notion of being essential may not be the most important of distinctions.

Fisk Harold A

2011-04-01

75

R&D ERL: Machine Protection System  

Energy Technology Data Exchange (ETDEWEB)

The Machine Protection System (MPS) is a device-safety system that is designed to prevent damage to hardware by generating interlocks, based upon the state of input signals generated by selected sub-system. It exists to protect key machinery such as the 50 kW and 1 MW RF Systems. When a fault state occurs, the MPS is capable of responding with an interlock signal within several microseconds. The Machine Protection System inputs are designed to be fail-safe. In addition, all fault conditions are latched and time-stamped. The ERL MPS is based on a National Instruments hardware platform, and is programmed by utilizing National Instruments development environment for a visual programming language.

Altinbas, Z.

2010-01-01

76

Development of a machine protection system for the Superconducting Beam Test Facility at Fermilab  

Energy Technology Data Exchange (ETDEWEB)

Fermilab's Superconducting RF Beam Test Facility currently under construction will produce electron beams capable of damaging the acceleration structures and the beam line vacuum chambers in the event of an aberrant accelerator pulse. The accelerator is being designed with the capability to operate with up to 3000 bunches per macro-pulse, 5Hz repetition rate and 1.5 GeV beam energy. It will be able to sustain an average beam power of 72 KW at the bunch charge of 3.2 nC. Operation at full intensity will deposit enough energy in niobium material to approach the melting point of 2500 C. In the early phase with only 3 cryomodules installed the facility will be capable of generating electron beam energies of 810 MeV and an average beam power that approaches 40 KW. In either case a robust Machine Protection System (MPS) is required to mitigate effects due to such large damage potentials. This paper will describe the MPS system being developed, the system requirements and the controls issues under consideration.

Warner, A.; Carmichael, L.; Church, M.; Neswold, R.; /Fermilab

2011-09-01

77

Development of a machine protection system for the Superconducting Beam Test Facility at Fermilab  

CERN Document Server

Fermilab's Superconducting RF Beam Test Facility currently under construction will produce electron beams capable of damaging the acceleration structures and the beam line vacuum chambers in the event of an aberrant accelerator pulse. The accelerator is being designed with the capability to operate with up to 3000 bunches per macro-pulse, 5Hz repetition rate and 1.5 GeV beam energy. It will be able to sustain an average beam power of 72 KW at the bunch charge of 3.2 nC. Operation at full intensity will deposit enough energy in niobium material to approach the melting point of 2500 {\\deg}C. In the early phase with only 3 cryomodules installed the facility will be capable of generating electron beam energies of 810 MeV and an average beam power that approaches 40 KW. In either case a robust Machine Protection System (MPS) is required to mitigate effects due to such large damage potentials. This paper will describe the MPS system being developed, the system requirements and the controls issues under consideratio...

Warner, A; Church, M; Neswold, R

2012-01-01

78

The safety of anginine in patients undergoing myocardial perfusion scintigraphy (MPS)- a nurses' perspective  

International Nuclear Information System (INIS)

Full text: Anginine-augmented MPS improves detection rate of myocardial viability and reversible ischaemia. However, anginine can cause significant hypotension. The aims of this study were to determine i) safety of anginine in patients with an intermediate to high risk of myocardial ischaemia undergoing MPS; ii) frequency and degree of fall in systolic blood pressure (SBP); iii) BP monitoring requirements; and iv) type of patient(s) prone to side effects. 63 patients (33M, 30F, mean age-67.2y) were included. Each was cannulated, drank two glasses of water, and lay supine prior to administration of anginine (1 x puff sublingually). 99Tcm-MIBI was administered 3-5 minutes later. BP measurements were obtained every five minutes for 20 minutes. SBP fell in 46/63 patients (range 5 - 40mmHg, mean 1 6mmHg, in 14 fall >20mmHg), and rose in 14/63. Maximal fall occurred 5-15 minutes post-administration of anginine (14 at 5min, 15 at 10min, 17 at 15min), returning toward baseline by 20 minutes in all patients. Seven patients developed a headache and two light-headedness; in all SBP fell >10mmHg. The quality of the scans was unaffected. There were 22(35%) abnormal studies - 14 reversible defects, two fixed defects, six cardiomyopathy (mean SBP tall 8.1mmHg, 8.6mmHg with normal study). LVEF was obtained in 33 patients; SBP fell in 24 (mean LVEF 57.8%), and rose in nine (mean LVEF 56.8%). The frequency and extent of hypotension in relation to age, sex, LVEF, opotension in relation to age, sex, LVEF, or scan findings was not statistically significant. Anginine is sate to administer to patients undergoing MPS. Careful monitoring of the BP is recommended during the initial 20 minutes post-administration. No particular patient type was identified at higher risk. Copyright (2000) The Australian and New Zealand Society of Nuclear Medicine Inc

79

Solar Stirling system development  

Science.gov (United States)

A low-cost, high-efficiency dish-Stirling solar thermal-electric power system is being developed for test in 1981. System components are the solar concentrator, receiver, fossil fuel combustor, thermal energy storage (TES), engine-generator, and power processing. System conceptualization is completed and design is in progress. Two receiver alternatives are being evaluated, a direct-coupled receiver-engine configuration with no TES and a heat pipe receiver with TES. System cost projections are being made. Goals for the system development task are (1) to develop an advanced dish-Stirling technology, utilizing a team of industrial contractors, (2) to demonstrate that technology at the system level, and (3) to determine how to achieve low production cost.

Stearns, J. W., Jr.; Won, Y. S.; Poon, P. T.; Das, R.; Chow, E. Y.

1979-01-01

80

An MPS-BNS Mixed Strategy Based on Game Theory for Wireless Mesh Networks  

Digital Repository Infrastructure Vision for European Research (DRIVER)

To achieve a valid effect of wireless mesh networks against selfish nodes and selfish behaviors in the packets forwarding, an approach named mixed MPS-BNS strategy is proposed in this paper. The proposed strategy is based on the Maximum Payoff Strategy (MPS) and the Best Neighbor Strategy (BNS). In this strategy, every node plays a packet forwarding game with its neighbors and records the total payoff of the game. After one round of play, each player chooses the MPS or BNS strategy for certai...

Huang, S. Q.; Wang, G. C.; Zhen, H. H.; Zhang, Z.

2013-01-01

 
 
 
 
81

Evolutionary Information System Development  

DEFF Research Database (Denmark)

This paper offers advice to companies and professionals that implement e-commerce systems in business organizations. Implementing e-commerce systems is different from traditional IT implementation and thus requires a new set of tools and skills. The need for a novel approach is illustrated and necessary items that must be taken into account are pointed out by narrating two stories of e-commerce implementation processes in wholesale companies. The empirical evidence suggests the following: Managing the continued development on an operational level requires operational insight and understanding of business priorities. On a more theoretical level this suggests that we must revise our current understanding of systems development to cope.

Kristensen, Jan

82

Power Systems Development Facility  

Energy Technology Data Exchange (ETDEWEB)

In support of technology development to utilize coal for efficient, affordable, and environmentally clean power generation, the Power Systems Development Facility (PSDF), located in Wilsonville, Alabama, has routinely demonstrated gasification technologies using various types of coals. The PSDF is an engineering scale demonstration of key features of advanced coal-fired power systems, including a Transport Gasifier, a hot gas particulate control device, advanced syngas cleanup systems, and high-pressure solids handling systems. This final report summarizes the results of the technology development work conducted at the PSDF through January 31, 2009. Twenty-one major gasification test campaigns were completed, for a total of more than 11,000 hours of gasification operation. This operational experience has led to significant advancements in gasification technologies.

Southern Company Services

2009-01-31

83

Numerical simulation on inertia controlled steam bubble condensation using MPS  

Science.gov (United States)

Bubble dynamics is quite complicated in the field of two-phase hydrodynamics because the interfacial heat and mass transfer is comprehensively affected by various influencing factors. Bubble condensation can be either thermally controlled or inertia controlled. Inertia controlled bubble condensation indicates that considerable pressure difference exists between the steam bubble and ambient liquid. In this paper, the inertia controlled steam bubble condensation was simulated using moving particle semi-implicit (MPS) method. The spherical bubble is located in the center of the cylindrical pool which makes the possibility of 2-D axisymmetric computation. The lateral and bottom wall are set to be rigid insulated boundaries and the top is free surface boundary. The pool volume must be large enough to eliminate the effects by pool wall. The initial bubble pressure ranges from 0.48 MPa to 3.98 MPa, and the initial bubble diameter ranges from 2 mm to 5 mm, and the ambient water pressure and temperature is 0.1 MPa and 70 °C, respectively. The bubble dynamics during condensation was investigated and the influences of initial bubble pressure and diameter were obtained. The bubble deformation during condensation is shown in figure 1, and the variations of bubble diameters and pressures during condensation are shown in figures 2 and 3, respectively.

Chong, Daotong; Ishiwatari, Yuki; Oka, Yoshiaki; Yan, Junjie; Liu, Jiping

2013-07-01

84

A DSP-Based Beam Current Monitoring System for Machine Protection Using Adaptive Filtering  

International Nuclear Information System (INIS)

The CEBAF accelerator at Jefferson Lab is currently using an analog beam current monitoring (BCM) system for its machine protection system (MPS), which has a loss accuracy of 2 micro-amps. Recent burn-through simulations predict catastrophic beam line component failures below 1 micro-amp of loss, resulting in a blind spot for the MPS. Revised MPS requirements target an ultimate beam loss accuracy of 250 nA. A new beam current monitoring system has been developed which utilizes modern digital receiver technology and digital signal processing concepts. The receiver employs a direct-digital down converter integrated circuit, mated with a Jefferson Lab digital signal processor VME card. Adaptive filtering is used to take advantage of current-dependent burn-through rates. Benefits of such a system include elimination of DC offsets, generic algorithm development, extensive filter options, and interfaces to UNIX-based control systems

85

Heatpipe power system development  

International Nuclear Information System (INIS)

This is the final report of a one-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The objective of the project was to develop a design approach that could enable the development of near-term, low-cost, space fission-power systems. Sixteen desired attributes were identified for such systems and detailed analyses were performed to verify that they are feasible. Preliminary design work was performed on one concept, the Heatpipe Power system (HPS). As a direct result of this project, funding was obtained from the National Aeronautics and Space Administration to build and test an HPS module. The module tests went well, and they now have funding to build a bimodal module

86

On the Kinematic Motion Primitives (kMPs - Theory and Application  

Directory of Open Access Journals (Sweden)

Experimental tests with the COmpliant huMANoid (COMAN were performed to show that the kMPs extracted from human subjects can be used to transfer the features of human locomotion to the gait of a robot.

FedericoLorenzoMoro

2012-10-01

87

Director, Division of Mathematical Sciences, ES-1520, MPS/DMS (Closes: 11/30/2005)  

Science.gov (United States)

... OF DUTIES: Serves as a member of the MPS Directorate leadership team and as the Foundation?s ... of the U.S. Office of Personnel Management. OPM approval will be based on the selectee?s background ...

88

RSMASS system model development  

International Nuclear Information System (INIS)

RSMASS system mass models have been used for more than a decade to make rapid estimates of space reactor power system masses. This paper reviews the evolution of the RSMASS models and summarizes present capabilities. RSMASS has evolved from a simple model used to make rough estimates of space reactor and shield masses to a versatile space reactor power system model. RSMASS uses unique reactor and shield models that permit rapid mass optimization calculations for a variety of space reactor power and propulsion systems. The RSMASS-D upgrade of the original model includes algorithms for the balance of the power system, a number of reactor and shield modeling improvements, and an automatic mass optimization scheme. The RSMASS-D suite of codes cover a very broad range of reactor and power conversion system options as well as propulsion and bimodal reactor systems. Reactor choices include in-core and ex-core thermionic reactors, liquid metal cooled reactors, particle bed reactors, and prismatic configuration reactors. Power conversion options include thermoelectric, thermionic, Stirling, Brayton, and Rankine approaches. Program output includes all major component masses and dimensions, efficiencies, and a description of the design parameters for a mass optimized system. In the past, RSMASS has been used as an aid to identify and select promising concepts for space power applications. The RSMASS modeling approach has been demonstrated to be a valuable tool for guiding optimid to be a valuable tool for guiding optimization of the power system design; consequently, the model is useful during system design and development as well as during the selection process. An improved in-core thermionic reactor system model RSMASS-T is now under development. The current development of the RSMASS-T code represents the next evolutionary stage of the RSMASS models. RSMASS-T includes many modeling improvements and is planned to be more user-friendly. RSMASS-T will be released as a fully documented, certified code at the end of 1998. A radioisotope space power system model RISMASS is also under development. RISMASS will optimize and predict system masses for radioisotope power sources coupled with close-spaced thermionic diodes. Although RSMASS-D models have been developed for a broad variety of space nuclear power and propulsion systems, only a few concepts will be included in the releasable RSMASS-T computer code. A follow-on effort is recommended to incorporate all previous models as well as solar power system models into one general code. The proposed Space Power and propulsion system MASS (SPMASS) code would provide a consistent analysis tool for comparing a very broad range of alternative power and propulsion systems for any required power level and operating conditions. As for RSMASS-T the SPMASS model should be a certified, fully documented computer code available for general use. The proposed computer program would provide space mission planners with the capability to quickly and cost effectively explore power system options for any space mission. The code should be applicable for power requirements from as low as a few milliwatts (solar and isotopic system options) to many megawatts for reactor power and propulsion systems

89

An MPS-BNS Mixed Strategy Based on Game Theory for Wireless Mesh Networks  

Science.gov (United States)

To achieve a valid effect of wireless mesh networks against selfish nodes and selfish behaviors in the packets forwarding, an approach named mixed MPS-BNS strategy is proposed in this paper. The proposed strategy is based on the Maximum Payoff Strategy (MPS) and the Best Neighbor Strategy (BNS). In this strategy, every node plays a packet forwarding game with its neighbors and records the total payoff of the game. After one round of play, each player chooses the MPS or BNS strategy for certain probabilities and updates the strategy accordingly. In MPS strategy, each node chooses a strategy that will get the maximum payoff according to its neighbor's strategy. In BNS strategy, each node follows the strategy of its neighbor with the maximum total payoff and then enters the next round of play. The simulation analysis has shown that MPS-BNS strategy is able to evolve to the maximum expected level of average payoff with faster speed than the pure BNS strategy, especially in the packets forwarding beginning with a low cooperation level. It is concluded that MPS-BNS strategy is effective in fighting against selfishness in different levels and can achieve a preferable performance. PMID:23401672

Huang, S. Q.; Wang, G. C.; Zhen, H. H.; Zhang, Z.

2013-01-01

90

Myocardial Perfusion Tomoscintigraphy With 99mTc MIBI (SPECT MPS 99mTc MIBI) In The Assessment Of Myocardial Viability  

International Nuclear Information System (INIS)

Prognosis of the patients with severe coronary artery disease is highly dependent on the degree of left ventricular dysfunction. Impaired contractile performance at rest is not necessarily due to Irreversible tissue damage but may relate to the 'hibernating' myocardium which has been defined as potentially reversible, chronic contractile dysfunction during prolonged, painless ischemia. Recovery of function may occur after successful revascularization only in the presence of substantial amount of viable myocardium. The development of highly precise and predictable diagnostic methods for the identification of viable myocardium and postoperative functional improvement is crucial for reasonable preoperative selection of the patients. Detection of hibernated myocardium Is a real diagnostic challenge when FDG-Fl8 PET, as the most accurate method for myocardial viability assessment is not available and Tl 201, as already established myocardial viability marker is not routinely used. Interest for the 99mTc labeled complexes, most often 99mTc MIBI, as proved myocardial perfusion but not yet viability tracer is constantly increasing, supported by the widespread availability of this radioisotope, its better imaging and radio dosimetric properties when compared to Ti 201. The aim of this study was to evaluate the diagnostic value of different SPECT MIBI Tc99m myocardial perfusion scintigraphy (MPS) modalities performed at rest and after nitrate administration, in the detection ofitrate administration, in the detection of myocardial viability (MV) arid to compare it with rest-redistribution TI 201 MPS (R-Red) and with the control SPECT MPS Tc99m MIBI study after revascularization. In a prospective study, 176 patients (34-77yrs, 25 female, 151 male), with angiographically proved coronary artery disease, most of them with previous myocardial infarction (143/176p (81%),>6 months) and LV dysfunction (110/176p (62%), EFG-MPS 41+/-16%) underwent ECG Gated SPECT MPS Tc 99m MIBI at rest and after s.l. administration of 0,5 mg Nitroglycerin (NTG). 20/176 p were examined also by TI 201 R-Red study and 20/176p were reevaluated after revascularization. Qualitative and quantitative analysis of rest, post-NTG and TI 201 Rest-Redistribution perfusion images (QL,QN) and functional analysis of rest and post-NTG Gated study (G) was done, using 17 segment model, grouped also according to vascular territories and 5-point scoring system for assessment of perfusion (0-normal, 1-mild,2-moderate,3-severe hypoperfusion, 4-absent perfusion) and wall motion (0-normal,l-mild,2-severe hypo kinetic, 3-akinetic,4-dyskinetic). A segment was predeterminated to be viable if the segment score was ?2 by perfusion (>50% photon activity by circumferential profiles) and ?2 by C-CG qated SPECT analysis (wall motion +/-, wall thickening-). Summed segment viability scores, total and separate for particular territory were. calculated and used to predict overall and territory viability. In a group of 176 pts, from a total of 2992 analyzed myocardial segments, 47% were nonviable by QL-Rest analysis, 31% by QN-Rest (p2) 25% by G-Rest (p2), 36% by QL-Rest-Red (p=0.3 vs. QL-Rest, ?2), 18% by QN-Rest-Red (p=04 vs. QN-Rest, ?2),), 33% by QL-NTG (p2), 19% by QN-NTG (p2), 16% by G-NTG (p=0.08 vs. QN-NTG, ?2), 28% by QL-NTG-Red (P=0.33 vs. QL-NTG, ?2), and 17% by QN-NTG-Red (p=0.4 vs. QN- NTG, ?2). Similar relation among different modalities was also observed during the assessment of total viability score: 26+/-9.1 by QN-Rest, 21.8+/-8.9 by G-Rest (p<0.01 vs. QN-Rest), 20.2+/-9.9 by QN-NTG (p<0.0l vs. G-Rest) and 16.7+/-9.4 by NTG-G (p<0.001 vs QN-NTG). Compared with TI 201 R-Red the sensitivity, specificity, positive and negative predictive values and accuracy for SPECT MPS Tc99m MIBI modalities were: 73%,100%,100%,37,5%,76% for QL-Rest, 84%,96%,99%,49%,86% for QN-Rest, 93,5%,81%,97%,67% 92% for G-Rest, 86%,94%, 99%,52%,87% for QL-NTG, 97%,90%,98%,81%,96% for QN-NTG and 97%,75%,96%82%,94% for G-NTG. Compared with the study after revascularization the sensitivity, specificity,

91

CheMPS2: a free open-source spin-adapted implementation of the density matrix renormalization group for ab initio quantum chemistry  

CERN Document Server

The density matrix renormalization group (DMRG) has become an indispensable numerical tool to find exact eigenstates of finite-size quantum systems with strong correlation. In the fields of condensed matter, nuclear structure and molecular electronic structure, it has significantly extended the system sizes that can be handled compared to full configuration interaction, without losing numerical accuracy. For quantum chemistry (QC), the most efficient implementations of DMRG require the incorporation of particle number, spin and point group symmetries in the underlying matrix product state (MPS) ansatz, as well as the use of so-called complementary operators. The symmetries introduce a sparse block structure in the MPS ansatz and in the intermediary contracted tensors. If a symmetry is non-abelian, the Wigner-Eckart theorem allows to factorize a tensor into a Clebsch-Gordan coefficient and a reduced tensor. In addition, the fermion signs have to be carefully tracked. Because of these challenges, implementing D...

Wouters, Sebastian; Ayers, Paul W; Van Neck, Dimitri

2013-01-01

92

Proceedings of the 1st Nordic Optimization Symposium - 10th Nordic MPS meeting, Copenhagen 2006  

DEFF Research Database (Denmark)

On behalf of the Technical University of Denmark, the Danish Operations Research Society and the Nordic Section of the Mathematical Programming Society we welcome you to Copenhagen and the 1st Nordic Optimization Symposium - the 10th meeting of the Nordic MPS. The meetings of the Nordic MPS have evolved to be more that just a meeting on Mathematical Programming. They are a forum for discussing a wide range of related areas and practical cases. In the organizing committee we wanted the name of the meeting to reflect this. We have therefore in agreement with the board of the Nordic MPS suggested to add a new title, that reflects the much broader field that is our playground at these meetings. Still the odd trustworthy title “Meeting of the Nordic MPS” has been maintained to demonstrate the origin of the symposium. It is our hope that future Nordic MPS meetings will carry on using this “double name”. The program includes 2 plenary lectures by Leo Kroon and Arne Drud and more than 50 contributed presentations. The symposium has this time expanded beyond our Nordic boundaries with participants from eg. the Netherlands, Italy and New Zealand. As a consequence the original 2 parallel streams we had in mind have extended to 3 throughout the symposium. It is our firm belief that this symposium will - like all the previous Nordic MPS meetings - be a fruitfull ground for collaboration and networking and therebye further tighten the ties between the Nordic countries in relation to optimization, Operations Research and Mathematical Programming. Finally we would like to thank our sponsors and supporter for their contributions. It has among other things made it possible to give free registration to a number of researchers from the Baltic countries and Ph.D. students in general. We wish you all an enjoyable 1st Nordic Optimization Symposium (10th Nordic MPS meeting) in Copenhagen.

Clausen, Jens; JØrgensen, Rene Munk

2006-01-01

93

The machine protection system for the R&D energy recovery LINAC  

Energy Technology Data Exchange (ETDEWEB)

The Machine Protection System (MPS) is a device-safety system that is designed to prevent damage to hardware by generating interlocks, based upon the state of input signals generated by selected sub-systems. It protects all the key machinery in the R&D Project called the Energy Recovery LINAC (ERL) against the high beam current. The MPS is capable of responding to a fault with an interlock signal within several microseconds. The ERL MPS is based on a National Instruments CompactRIO platform, and is programmed by utilizing National Instruments' development environment for a visual programming language. The system also transfers data (interlock status, time of fault, etc.) to the main server. Transferred data is integrated into the pre-existing software architecture which is accessible by the operators. This paper will provide an overview of the hardware used, its configuration and operation, as well as the software written both on the device and the server side.

Altinbas, Z.; Kayran, D.; Jamilkowski, J.; Lee, R.C.; Oerter, B.

2011-03-28

94

Geological disposal system development  

Energy Technology Data Exchange (ETDEWEB)

Spent fuel inventories to be disposed of finally and design base spent fuel were determined. Technical and safety criteria for a geological repository system in Korea were established. Based on the properties of spent PWR and CANDU fuels, seven repository alternatives were developed and the most promising repository option was selected by the pair-wise comparison method from the technology point of view. With this option preliminary conceptual design studies were carried out. Several module, e.g., gap module, congruent release module were developed for the overall assessment code MASCOT-K. The prominent overseas databases such as OECD/NEA FEP list were are fully reviewed and then screened to identify the feasible ones to reflect the Korean geo-hydrological conditions. In addition to this the well known scenario development methods such as PID, RES were reviewed. To confirm the radiological safety of the proposed KAERI repository concept the preliminary PA was pursued. Thermo-hydro-mechanical analysis for the near field of repository were performed to verify thermal and mechanical stability for KAERI repository system. The requirements of buffer material were analyzed, and based on the results, the quantitative functional criteria for buffer material were established. The hydraulic and swelling property, mechanical properties, and thermal conductivity, the organic carbon content, and the evolution of pore water chemistry were investigated. Based on the results, the candidate buffer material was selected.

Kang, Chul Hyung; Kuh, J. E.; Kim, S. K. and others

2000-04-01

95

Geological disposal system development  

International Nuclear Information System (INIS)

Spent fuel inventories to be disposed of finally and design base spent fuel were determined. Technical and safety criteria for a geological repository system in Korea were established. Based on the properties of spent PWR and CANDU fuels, seven repository alternatives were developed and the most promising repository option was selected by the pair-wise comparison method from the technology point of view. With this option preliminary conceptual design studies were carried out. Several module, e.g., gap module, congruent release module were developed for the overall assessment code MASCOT-K. The prominent overseas databases such as OECD/NEA FEP list were are fully reviewed and then screened to identify the feasible ones to reflect the Korean geo-hydrological conditions. In addition to this the well known scenario development methods such as PID, RES were reviewed. To confirm the radiological safety of the proposed KAERI repository concept the preliminary PA was pursued. Thermo-hydro-mechanical analysis for the near field of repository were performed to verify thermal and mechanical stability for KAERI repository system. The requirements of buffer material were analyzed, and based on the results, the quantitative functional criteria for buffer material were established. The hydraulic and swelling property, mechanical properties, and thermal conductivity, the organic carbon content, and the evolution of pore water chemistry were investigated. Based on the results, the candidate buffer material was selected

96

Numerical analysis of crust formation in molten core-concrete interaction using MPS method  

International Nuclear Information System (INIS)

A two-dimensional code is developed for molten core-concrete interaction (MCCI) based on Moving Particle Semi-implicit (MPS) method. Heat transfer is calculated without any specific correlations. A particle can be changed to a moving (fluid) or fixed (solid) particle corresponding to its enthalpy, which provide the phase change model for particles. The phase change model is verified by one-dimensional test calculations. Nucleate boiling and radiation heat transfers are considered between the core debris and the water pool. The developed code is applied to SWISS-2 experiment in which stainless steel is used as the melt material. Calculated heat flux to the water pool agrees well with the experiment, though the ablation speed in the concrete is a little slower. A stable crust is formed in a short time after water is poured in and the heat flux to the water pool rapidly decreases. MACE-M0 using corium is also analyzed. The ablation speed of concrete is slower than that of SWISS-2 because of low heat conduction in corium. An unlimited geometry is analyzed by setting the cyclic boundary condition on the sides. When the crust is broken by the decomposition gas, heat transfer to the water pool is kept high for a longer time because the crust re-formation is delayed. (author)

97

Bone marrow transplantation in patients with storage diseases: a developing country experience  

Directory of Open Access Journals (Sweden)

Full Text Available Bone marrow transplantation (BMT is a therapeutic option for patients with genetic storage diseases. Between 1979 and 2002, eight patients, four females and four males (1 to 13 years old were submitted to this procedure in our center. Six patients had mucopolysaccharidosis (MPS I in 3; MPS III in one and MPS VI in 2, one had adrenoleukodystrophy (ALD and one had Gaucher disease. Five patients had related and three unrelated BMT donor. Three patients developed graft versus host disease (two MPS I and one MPS VI and died between 37 and 151 days after transplantation. Five patients survived 4 to 16 years after transplantation. Three patients improved (one MPS I; one MPS VI and the Gaucher disease patient, one patient had no disease progression (ALD and in one patient this procedure did not change the natural course of the disease (MPS III.

Lange Marcos C.

2006-01-01

98

Characterization of light-cured dental composites prepared from Bis-GMA/TEEDGDMA and Bis-GMA/MPS mistures  

Scientific Electronic Library Online (English)

Full Text Available SciELO Argentina | Language: English Abstract in english The aim of this study was to prepare light-cured dental composites and to evaluate their physical, chemical and mechanical properties. Experimental composites were prepared from 2, 2 bis [4-(2-hidroxy 3-metacriloxypropoxi) phenyl] propane (Bis-GMA), tetraethyleneglycol dimethacrylate (TEEGDMA), 3-me [...] thacryloxypropyl trimethoxysilane (MPS) and a hybrid filler consisting of quartz and colloidal silica particles (Aerosil 90). The initiation system was based on the pair Camphorquinone (CQ) / N, N dimethylaminoethylmethacrylate (DMAEMA). The experimental composites and a commercial dental composite used as reference (Charisma®) were submitted to determinations of depth of cure, water absorption and solubility, compressive and diametral tensile strengths, and elastic modulus, according to the indications of the ISO standards. The experimental resins presented adequate values for most of the analyzed properties, except for compressive strengths. In the Bis-GMA/ MPS/quartz-aerosil composite a better integration between filler and matrix was observed. The Bis-GMA/TEEGDMA/quartz-aerosil composite showed the best performance in regards to depth of cure, solubility in water, diametral tensile strength and elastic modulus. The properties of this composite were better than those of the commercial reference material, except for compressive strength.

Y., Veranes; D., Correa; J. M., Martin; R., Krael; R., Alvarez.

2006-01-01

99

Characterization of light-cured dental composites prepared from Bis-GMA/TEEDGDMA and Bis-GMA/MPS mistures  

Scientific Electronic Library Online (English)

Full Text Available SciELO Argentina | Language: English Abstract in english The aim of this study was to prepare light-cured dental composites and to evaluate their physical, chemical and mechanical properties. Experimental composites were prepared from 2, 2 bis [4-(2-hidroxy 3-metacriloxypropoxi) phenyl] propane (Bis-GMA), tetraethyleneglycol dimethacrylate (TEEGDMA), 3-me [...] thacryloxypropyl trimethoxysilane (MPS) and a hybrid filler consisting of quartz and colloidal silica particles (Aerosil 90). The initiation system was based on the pair Camphorquinone (CQ) / N, N dimethylaminoethylmethacrylate (DMAEMA). The experimental composites and a commercial dental composite used as reference (Charisma®) were submitted to determinations of depth of cure, water absorption and solubility, compressive and diametral tensile strengths, and elastic modulus, according to the indications of the ISO standards. The experimental resins presented adequate values for most of the analyzed properties, except for compressive strengths. In the Bis-GMA/ MPS/quartz-aerosil composite a better integration between filler and matrix was observed. The Bis-GMA/TEEGDMA/quartz-aerosil composite showed the best performance in regards to depth of cure, solubility in water, diametral tensile strength and elastic modulus. The properties of this composite were better than those of the commercial reference material, except for compressive strength.

Y., Veranes; D., Correa; J. M., Martin; R., Krael; R., Alvarez.

100

Power Systems Development Facility  

Energy Technology Data Exchange (ETDEWEB)

This report discusses Test Campaign TC12 of the Kellogg Brown & Root, Inc. (KBR) Transport Gasifier train with a Siemens Westinghouse Power Corporation (SW) particle filter system at the Power Systems Development Facility (PSDF) located in Wilsonville, Alabama. The Transport Gasifier is an advanced circulating fluidized-bed reactor designed to operate as either a combustor or a gasifier using a particulate control device (PCD). While operating as a gasifier, either air or oxygen can be used as the oxidant. Test run TC12 began on May 16, 2003, with the startup of the main air compressor and the lighting of the gasifier start-up burner. The Transport Gasifier operated until May 24, 2003, when a scheduled outage occurred to allow maintenance crews to install the fuel cell test unit and modify the gas clean-up system. On June 18, 2003, the test run resumed when operations relit the start-up burner, and testing continued until the scheduled end of the run on July 14, 2003. TC12 had a total of 733 hours using Powder River Basin (PRB) subbituminous coal. Over the course of the entire test run, gasifier temperatures varied between 1,675 and 1,850 F at pressures from 130 to 210 psig.

None

2003-07-01

 
 
 
 
101

Power Systems Development Facility  

International Nuclear Information System (INIS)

The objective of the PSDF would be to provide a modular facility which would support the development of advanced, pilot-scale, coal-based power systems and hot gas clean-up components. These pilot-scale components would be designed to be large enough so that the results can be related and projected to commercial systems. The facility would use a modular approach to enhance the flexibility and capability for testing; consequently, overall capital and operating costs when compared with stand-alone facilities would be reduced by sharing resources common to different modules. The facility would identify and resolve technical barrier, as well as-provide a structure for long-term testing and performance assessment. It is also intended that the facility would evaluate the operational and performance characteristics of the advanced power systems with both bituminous and subbituminous coals. Five technology-based experimental modules are proposed for the PSDF: (1) an advanced gasifier module, (2) a fuel cell test module, (3) a PFBC module, (4) a combustion gas turbine module, and (5) a module comprised of five hot gas cleanup particulate control devices. The final module, the PCD, would capture coal-derived ash and particles from both the PFBC and advanced gasifier gas streams to provide for overall particulate emission control, as well as to protect the combustion turbine and the fuel cell

102

Advanced Dewatering Systems Development  

Energy Technology Data Exchange (ETDEWEB)

A new fine coal dewatering technology has been developed and tested in the present work. The work was funded by the Solid Fuels and Feedstocks Grand Challenge PRDA. The objective of this program was to 'develop innovative technical approaches to ensure a continued supply of environmentally sound solid fuels for existing and future combustion systems with minimal incremental fuel cost.' Specifically, this solicitation is aimed at developing technologies that can (i) improve the efficiency or economics of the recovery of carbon when beneficiating fine coal from both current production and existing coal slurry impoundments and (ii) assist in the greater utilization of coal fines by improving the handling characteristics of fine coal via dewatering and/or reconstitution. The results of the test work conducted during Phase I of the current project demonstrated that the new dewatering technologies can substantially reduce the moisture from fine coal, while the test work conducted during Phase II successfully demonstrated the commercial viability of this technology. It is believed that availability of such efficient and affordable dewatering technology is essential to meeting the DOE's objectives.

R.H. Yoon; G.H. Luttrell

2008-07-31

103

CheMPS2: A free open-source spin-adapted implementation of the density matrix renormalization group for ab initio quantum chemistry  

Science.gov (United States)

The density matrix renormalization group (DMRG) has become an indispensable numerical tool to find exact eigenstates of finite-size quantum systems with strong correlation. In the fields of condensed matter, nuclear structure and molecular electronic structure, it has significantly extended the system sizes that can be handled compared to full configuration interaction, without losing numerical accuracy. For quantum chemistry (QC), the most efficient implementations of DMRG require the incorporation of particle number, spin and point group symmetries in the underlying matrix product state (MPS) ansatz, as well as the use of so-called complementary operators. The symmetries introduce a sparse block structure in the MPS ansatz and in the intermediary contracted tensors. If a symmetry is non-abelian, the Wigner-Eckart theorem allows to factorize a tensor into a Clebsch-Gordan coefficient and a reduced tensor. In addition, the fermion signs have to be carefully tracked. Because of these challenges, implementing DMRG efficiently for QC is not straightforward. Efficient and freely available implementations are therefore highly desired. In this work we present CheMPS2, our free open-source spin-adapted implementation of DMRG for ab initio QC. Around CheMPS2, we have implemented the augmented Hessian Newton-Raphson complete active space self-consistent field method, with exact Hessian. The bond dissociation curves of the 12 lowest states of the carbon dimer were obtained at the DMRG(28 orbitals, 12 electrons, DSU(2)=2500)/cc-pVDZ level of theory. The contribution of 1s core correlation to the X1?g+ bond dissociation curve of the carbon dimer was estimated by comparing energies at the DMRG(36o, 12e, DSU(2)=2500)/cc-pCVDZ and DMRG-SCF(34o, 8e, DSU(2)=2500)/cc-pCVDZ levels of theory.

Wouters, Sebastian; Poelmans, Ward; Ayers, Paul W.; Van Neck, Dimitri

2014-06-01

104

Development of two-dimensional position sensitive detector systems using multi-pixel photon counters for neutron experiments  

Science.gov (United States)

Neutron scattering experiments are indispensable to the structural analysis of many types of condensed matter and in the development of advanced materials. A high resolution detector system and a high counting rate detector system, both utilizing a neutron scintillator and multi-pixel photon counters (MPPCs), have been developed at the High-Energy Accelerator Research Organization (KEK). These systems will be used in the BL16 and BL06 neutron scattering instruments at the Material and Life Science Facility (MLF) in the Japan Proton Accelerator Research Complex (J-PARC). The high resolution detector is an MPPC position-sensitive detector (MPS) with a 105×128 mm2 detection area and has positional resolution of 1 mm. The high counting rate detector is an MPPC Pixel detector (MPIX) with a 320×40 mm2 detection area. The maximum counting rate is 4 million counts per second (Mcps).

Satoh, Setsuo; Muto, Suguru

2013-12-01

105

Power Systems Development Facility  

Energy Technology Data Exchange (ETDEWEB)

This report discusses Test Campaign TC15 of the Kellogg Brown & Root, Inc. (KBR) Transport Gasifier train with a Siemens Power Generation, Inc. (SPG) particle filter system at the Power Systems Development Facility (PSDF) located in Wilsonville, Alabama. The Transport Gasifier is an advanced circulating fluidized-bed reactor designed to operate as either a combustor or gasifier using a particulate control device (PCD). While operating as a gasifier, either air or oxygen can be used as the oxidant. Test run TC15 began on April 19, 2004, with the startup of the main air compressor and the lighting of the gasifier startup burner. The Transport Gasifier was shutdown on April 29, 2004, accumulating 200 hours of operation using Powder River Basin (PRB) subbituminous coal. About 91 hours of the test run occurred during oxygen-blown operations. Another 6 hours of the test run was in enriched-air mode. The remainder of the test run, approximately 103 hours, took place during air-blown operations. The highest operating temperature in the gasifier mixing zone mostly varied from 1,800 to 1,850 F. The gasifier exit pressure ran between 200 and 230 psig during air-blown operations and between 110 and 150 psig in oxygen-enhanced air operations.

Southern Company Services

2004-04-30

106

POWER SYSTEMS DEVELOPMENT FACILITY  

Energy Technology Data Exchange (ETDEWEB)

This report discusses test campaign GCT4 of the Kellogg Brown & Root, Inc. (KBR) transport reactor train with a Siemens Westinghouse Power Corporation (Siemens Westinghouse) particle filter system at the Power Systems Development Facility (PSDF) located in Wilsonville, Alabama. The transport reactor is an advanced circulating fluidized-bed reactor designed to operate as either a combustor or a gasifier using one of two possible particulate control devices (PCDs). The transport reactor was operated as a pressurized gasifier during GCT4. GCT4 was planned as a 250-hour test run to continue characterization of the transport reactor using a blend of several Powder River Basin (PRB) coals and Bucyrus limestone from Ohio. The primary test objectives were: Operational Stability--Characterize reactor loop and PCD operations with short-term tests by varying coal-feed rate, air/coal ratio, riser velocity, solids-circulation rate, system pressure, and air distribution. Secondary objectives included the following: Reactor Operations--Study the devolatilization and tar cracking effects from transient conditions during transition from start-up burner to coal. Evaluate the effect of process operations on heat release, heat transfer, and accelerated fuel particle heat-up rates. Study the effect of changes in reactor conditions on transient temperature profiles, pressure balance, and product gas composition. Effects of Reactor Conditions on Synthesis Gas Composition--Evaluate the effect of air distribution, steam/coal ratio, solids-circulation rate, and reactor temperature on CO/CO{sub 2} ratio, synthesis gas Lower Heating Value (LHV), carbon conversion, and cold and hot gas efficiencies. Research Triangle Institute (RTI) Direct Sulfur Recovery Process (DSRP) Testing--Provide syngas in support of the DSRP commissioning. Loop Seal Operations--Optimize loop seal operations and investigate increases to previously achieved maximum solids-circulation rate.

Unknown

2002-11-01

107

Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex.  

Science.gov (United States)

The binucleate pathogen Giardia intestinalis is a highly divergent eukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint complex (MCC) proteins. However, Giardia has some MCC components (Bub3, Mad2, and Mps1) and proteins from the cohesin system (Smc1 and Smc3). Mad2 localizes to the cytoplasm, but Bub3 and Mps1 are either located on chromosomes or in the cytoplasm, depending on the cell cycle stage. Depletion of Bub3, Mad2, or Mps1 resulted in a lowered mitotic index, errors in chromosome segregation (including lagging chromosomes), and abnormalities in spindle morphology. During interphase, MCC knockdown cells have an abnormal number of nuclei, either one nucleus usually on the left-hand side of the cell or two nuclei with one mislocalized. These results suggest that the minimal set of MCC proteins in Giardia play a major role in regulating many aspects of mitosis, including chromosome segregation, coordination of mitosis between the two nuclei, and subsequent nuclear positioning. The critical importance of MCC proteins in an organism that lacks their canonical target, the APC/C, suggests a broader role for these proteins and hints at new pathways to be discovered. PMID:25057014

Vicente, Juan-Jesus; Cande, W Zacheus

2014-09-15

108

The study of pressure source term in moving particle semi-implicit (MPS)  

International Nuclear Information System (INIS)

In this paper pressure source terms proposed by different researcher are compared in term of pressure stability. In Moving Particle Semi-Implicit (MPS) method, the pressure error is compensated back into pressure Poisson equation as source term in order to enforce the incompressibility. However the non physical pressure fluctuation still remains an open problem in MPS method. In present study the hydrostatic model is used as example to study the pressure stability for each of the pressure source terms. The pressure at the fixed point over time is plotted and the fluctuation from the theoretical pressure is discussed.

109

The study of pressure source term in moving particle semi-implicit (MPS)  

Science.gov (United States)

In this paper pressure source terms proposed by different researcher are compared in term of pressure stability. In Moving Particle Semi-Implicit (MPS) method, the pressure error is compensated back into pressure Poisson equation as source term in order to enforce the incompressibility. However the non physical pressure fluctuation still remains an open problem in MPS method. In present study the hydrostatic model is used as example to study the pressure stability for each of the pressure source terms. The pressure at the fixed point over time is plotted and the fluctuation from the theoretical pressure is discussed.

Ng, Y. L.; Ng, K. C.; Yusoff, M. Z.

2013-06-01

110

Numerical simulation of sloshing with large deforming free surface by MPS-LES method  

Science.gov (United States)

Moving particle semi-implicit (MPS) method is a fully Lagrangian particle method which can easily solve problems with violent free surface. Although it has demonstrated its advantage in ocean engineering applications, it still has some defects to be improved. In this paper, MPS method is extended to the large eddy simulation (LES) by coupling with a sub-particle-scale (SPS) turbulence model. The SPS turbulence model turns into the Reynolds stress terms in the filtered momentum equation, and the Smagorinsky model is introduced to describe the Reynolds stress terms. Although MPS method has the advantage in the simulation of the free surface flow, a lot of non-free surface particles are treated as free surface particles in the original MPS model. In this paper, we use a new free surface tracing method and the key point is "neighbor particle". In this new method, the zone around each particle is divided into eight parts, and the particle will be treated as a free surface particle as long as there are no "neighbor particles" in any two parts of the zone. As the number density parameter judging method has a high efficiency for the free surface particles tracing, we combine it with the neighbor detected method. First, we select out the particles which may be mistreated with high probabilities by using the number density parameter judging method. And then we deal with these particles with the neighbor detected method. By doing this, the new mixed free surface tracing method can reduce the mistreatment problem efficiently. The serious pressure fluctuation is an obvious defect in MPS method, and therefore an area-time average technique is used in this paper to remove the pressure fluctuation with a quite good result. With these improvements, the modified MPS-LES method is applied to simulate liquid sloshing problems with large deforming free surface. Results show that the modified MPS-LES method can simulate the large deforming free surface easily. It can not only capture the large impact pressure accurately on rolling tank wall but also can generate all physical phenomena successfully. The good agreement between numerical and experimental results proves that the modified MPS-LES method is a good CFD methodology in free surface flow simulations.

Pan, Xu-jie; Zhang, Huai-xin; Sun, Xue-yao

2012-12-01

111

Basic study on uncertainty related to failure phenomenon by MPS method or DEM  

Science.gov (United States)

MPS (Moving Particle Semi-implicit) method or DEM (Discrete Element Method) is useful to simulate strong nonlinear phenomenon like slope failure. The calculated result, however, is often affected by very small difference of model or material property, even difference of computation environment. It is shown that the variation of the response does not depend on the variation of model stiffness when the nonlinearity is strong, through numerical simulation of slope failure by MPS. It is also shown that the distribution of moving distance of falling rock does not affected by variation of initial position in DEM simulation though the individual response is highly sensitive to the position.

Yoshida, Ikumasa; Ohba, Keisuke; Ishimaru, Makoto

112

The National Institutes of Health Microphysiological Systems Program focuses on a critical challenge in the drug discovery pipeline.  

Science.gov (United States)

The National Institutes of Health has partnered with the US Food and Drug Administration and the Defense Advanced Research Projects Agency to accelerate the development of human microphysiological systems (MPS) that address challenges faced in predictive toxicity assessment and efficacy analysis of new molecular entities during the preclinical phase of drug development. Use of human MPS could provide better models for predicting the efficacy of new molecular entities in clinical trials. It is also anticipated that improvements in predicting drug toxicities early in the drug development process through the use of MPS or human organs-on-a-chip will decrease the need to withdraw new therapies from the market and minimize or eliminate deaths due to unidentified drug toxicities. PMID:24565163

Sutherland, Margaret L; Fabre, Kristin M; Tagle, Danilo A

2013-01-01

113

POWER SYSTEMS DEVELOPMENT FACILITY  

Energy Technology Data Exchange (ETDEWEB)

This report discusses test campaign GCT3 of the Halliburton KBR transport reactor train with a Siemens Westinghouse Power Corporation (Siemens Westinghouse) particle filter system at the Power Systems Development Facility (PSDF) located in Wilsonville, Alabama. The transport reactor is an advanced circulating fluidized-bed reactor designed to operate as either a combustor or a gasifier using one of two possible particulate control devices (PCDs). The transport reactor was operated as a pressurized gasifier during GCT3. GCT3 was planned as a 250-hour test run to commission the loop seal and continue the characterization of the limits of operational parameter variations using a blend of several Powder River Basin coals and Bucyrus limestone from Ohio. The primary test objectives were: (1) Loop Seal Commissioning--Evaluate the operational stability of the loop seal with sand and limestone as a bed material at different solids circulation rates and establish a maximum solids circulation rate through the loop seal with the inert bed. (2) Loop Seal Operations--Evaluate the loop seal operational stability during coal feed operations and establish maximum solids circulation rate. Secondary objectives included the continuation of reactor characterization, including: (1) Operational Stability--Characterize the reactor loop and PCD operations with short-term tests by varying coal feed, air/coal ratio, riser velocity, solids circulation rate, system pressure, and air distribution. (2) Reactor Operations--Study the devolatilization and tar cracking effects from transient conditions during transition from start-up burner to coal. Evaluate the effect of process operations on heat release, heat transfer, and accelerated fuel particle heat-up rates. Study the effect of changes in reactor conditions on transient temperature profiles, pressure balance, and product gas composition. (3) Effects of Reactor Conditions on Syngas Composition--Evaluate the effect of air distribution, steam/coal ratio, solids circulation rate, and reactor temperature on CO/CO{sub 2} ratio, H{sub 2}/converted carbon ratio, gasification rates, carbon conversion, and cold and hot gas efficiencies. Test run GCT3 was started on December 1, 2000, with the startup of the thermal oxidizer fan, and was completed on February 1, 2001. This test was conducted in two parts; the loop seal was commissioned during the first part of this test run from December 1 through 15, which consisted of hot inert solids circulation testing. These initial tests provided preliminary data necessary to understand different parameters associated with the operation and performance of the loop seal. The loop seal was tested with coal feed during the second part of the test run and additional data was gathered to analyze reactor operations and to identify necessary modifications to improve equipment and process performance. In the second part of GCT3, the gasification portion of the test, from January 20 to February 1, 2001, the mixing zone and riser temperatures were varied between 1,675 and 1,825 F at pressures ranging from 200 to 240 psig. There were 306 hours of solid circulation and 184 hours of coal feed attained in GCT3.

Unknown

2002-05-01

114

MEASUREMENT PROCESS OF SOFTWARE DEVELOPMENT PROJECTS FOR SUPPORTING STRATEGIC BUSINESS OBJECTIVES IN SOFTWARE DEVELOPING COMPANIES  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Software developing companies work in a competitive market and are often challenged to make business decisions with impact on competitiveness. Models accessing maturity for software development processes quality, such as CMMI and MPS-BR, comprise process measurements systems (PMS). However, these models are not necessarily suitable to support business decisions, neither to achieve strategic goals. The objective of this work is to analyze how the PMS of software development projects could supp...

Sandra Lais Pedroso; Leonardo Rocha de Oliveira

2013-01-01

115

Busing Cuts Cause MPS to Lag in Spending Increases. Research Brief. Volume 90, Number 8  

Science.gov (United States)

The Forum's 16th annual report on public schooling in Southeastern Wisconsin reveals that spending increased 4% in Southeastern Wisconsin school districts to $2.8 billion last year, although the Milwaukee Public Schools (MPS) experienced a significantly smaller increase (2.7%). Part of this relatively small increase can be attributed to the…

Public Policy Forum, 2002

2002-01-01

116

MPS Charter Students Outscore City, UWM. Research Brief. Volume 90, Number 10  

Science.gov (United States)

In its annual analysis of Milwaukee charter schools, the Forum found that Milwaukee Public Schools (MPS) charter school students substantially outperform University of Wisconsin-Milwaukee (UWM) and City charter school students, especially at the elementary school level. The charter school movement continues to gain momentum across the country as…

Public Policy Forum, 2002

2002-01-01

117

Numerical analysis of isothermal JET injection into a denser liquid pool using RD-MPS Method  

Energy Technology Data Exchange (ETDEWEB)

In this study, the rigid body dynamics coupled moving particle semi-implicit (RD-MPS) method was used to simulate a plunging liquid jet penetrating into a denser liquid pool. The phenomenon is related to fuel-coolant interactions (FCI) during severe accidents in nuclear power plants when coolant water is forcedly injected into a melt pool. A numerical particle method like MPS enables to simulate the complex multiphase flow in that significant deformation of fluids occurs due to its inherent grid less algorithm. However, the MPS method alone cannot continue the calculation for a long time as shown in the Ikea's work due to the large deformation of fluid surfaces and the difference in both liquid densities. In the RD-MPS method, the rigid body dynamics was coupled with the moving particle semi-implicit method to increase the overall stability of calculations and to calculate the multi-phase behavior of fluids. We performed two and three dimensional calculations to simulate jet penetration behaviors in a denser liquid pool, and the result was in good agreement with that of experiment. The simulation results suggested that the coupled model be useful in simulating dynamic interactions of multi-phase incompressible fluids as well as that the 3-D simulation for the plunging jet in a confined geometry predicted better agreement with experimental results than the 2-D simulation did.

Park, S. [KEPCO Nuclear Fuel, Daejeon (Korea, Republic of); Park, H. S. [POSTECH, Pohang (Korea, Republic of); Jeun, G. [Hanyang Univ., Seoul (Korea, Republic of)

2012-03-15

118

Numerical analysis of isothermal JET injection into a denser liquid pool using RD-MPS Method  

International Nuclear Information System (INIS)

In this study, the rigid body dynamics coupled moving particle semi-implicit (RD-MPS) method was used to simulate a plunging liquid jet penetrating into a denser liquid pool. The phenomenon is related to fuel-coolant interactions (FCI) during severe accidents in nuclear power plants when coolant water is forcedly injected into a melt pool. A numerical particle method like MPS enables to simulate the complex multiphase flow in that significant deformation of fluids occurs due to its inherent grid less algorithm. However, the MPS method alone cannot continue the calculation for a long time as shown in the Ikea's work due to the large deformation of fluid surfaces and the difference in both liquid densities. In the RD-MPS method, the rigid body dynamics was coupled with the moving particle semi-implicit method to increase the overall stability of calculations and to calculate the multi-phase behavior of fluids. We performed two and three dimensional calculations to simulate jet penetration behaviors in a denser liquid pool, and the result was in good agreement with that of experiment. The simulation results suggested that the coupled model be useful in simulating dynamic interactions of multi-phase incompressible fluids as well as that the 3-D simulation for the plunging jet in a confined geometry predicted better agreement with experimental results than the 2-D simulation did

119

Simulation of the QUEOS Experiment using Rigid Dynamic-Moving Particle Semi-Implicit (RD-MPS) Method  

Energy Technology Data Exchange (ETDEWEB)

Particle dissipation and mixing in liquid are common multiphase phenomena not only in nature and but also in industrial processes. Also, It is one of important phenomena in nuclear safety analysis on severe accidents associated with the coolability of the corium debris bed, in which the characteristics of the porous corium debris bed such as local porosity distribution, debris bed configuration, debris size distribution, porous structure etc., determined by the corium jet breakup, precipitation, and mixing processes are considered to be of importance. Therefore, we developed a new computational tool, called ADDA (Analysis of Debris Dynamics and Agglomeration), based on an enhanced MPS (Moving Particle Semi-implicit) algorithm (Park, 2011) to understand the complex debris dissipation and mixing phenomena and identify the roles of the debris characteristics in the process and verified against the QUEOS experiment (Meyer, 1996; 1997) performed at FzK in Germany

Park, Shane [KEPCO Nuclear Fuel Co., Daejeon (Korea, Republic of); Park, Hyun Sun [SINEWSTEK, Stockholm (Sweden); Jeun, Gyoo Dong [Hanyang University, Seoul (Korea, Republic of)

2011-05-15

120

Simulation of the QUEOS Experiment using Rigid Dynamic-Moving Particle Semi-Implicit (RD-MPS) Method  

International Nuclear Information System (INIS)

Particle dissipation and mixing in liquid are common multiphase phenomena not only in nature and but also in industrial processes. Also, It is one of important phenomena in nuclear safety analysis on severe accidents associated with the coolability of the corium debris bed, in which the characteristics of the porous corium debris bed such as local porosity distribution, debris bed configuration, debris size distribution, porous structure etc., determined by the corium jet breakup, precipitation, and mixing processes are considered to be of importance. Therefore, we developed a new computational tool, called ADDA (Analysis of Debris Dynamics and Agglomeration), based on an enhanced MPS (Moving Particle Semi-implicit) algorithm (Park, 2011) to understand the complex debris dissipation and mixing phenomena and identify the roles of the debris characteristics in the process and verified against the QUEOS experiment (Meyer, 1996; 1997) performed at FzK in Germany

 
 
 
 
121

The Guided System Development Framework  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The Service-Oriented Computing paradigm has had significant influence on the Internet. With the emergence of this paradigm, it is important to provide tools that help developers designing and verifying such systems. In this article, we present the Guided System Development (GSD) Framework that aids and guides the developer on the specification of the system being developed, on choosing the appropriate standard protocols suites that achieve the required security properties, on providing an imp...

Carvalho Quaresma, Jose Nuno; Probst, Christian W.; Nielson, Flemming

2011-01-01

122

Evaluation of possible failure of the mononuclear phagocyte system after total splenectomy in rats  

Directory of Open Access Journals (Sweden)

Full Text Available Young and adult Wistar rats were submitted to total splenectomy and compared to animals not submitted to any surgical manipulation in order to evaluate the phagocytic function of spleen. The animals were infected with Escherichia coli labeled with technetium-99m and killed 20 minutes later. Liver, lung, spleen and a blood clot sample were taken. No significant differences were found in the percentage of bacterial radioactivity uptake in mononuclear phagocyte system (MPS organs in young and adult splenectomized rats. However, phagocytosis index by macrophages of MPS organs was smaller in splenectomized animals than in control group. Splenectomized rats were associated with a higher blood bacterial radioactivity uptake than animals of the control group (p<0.0001 due to a larger bacterial remnant in the bloodstream. This finding suggested that some failure in the MPS occurred in the absence of the spleen, demonstrating the need to develop alternative surgical techniques for total splenectomy.

Marques Ruy Garcia

2004-01-01

123

Development of a multifunctional particle spectrometer for space radiation imaging  

International Nuclear Information System (INIS)

For future exploration of the solar system, the European Space Agency (ESA) is planning missions to Mercury (BepiColombo), the Sun (SolarOrbiter) and to the moons of Jupiter and Saturn. The expected intensity of radiation during such missions is hazardous for the scientific instruments and the satellite. To extend the lifetime of the satellite and its payload a multifunctional particle spectrometer (MPS) is being developed. The basic function of the MPS is to send an alarm signal to the satellite control system during periods of high radiation. In addition the MPS is a scientific instrument that will unfold the composition of the different contributing particles on-line by the dE/dx versus E method. The energy spectrum and angular distribution of the particles will be recorded as well. This article describes the main requirements and the base line design for the MPS. A readout scheme consisting of a 32 channel ASIC from IDEAS is proposed and the signal filtering algorithm will run on a digital signal processor based on FPGA technology. Results are shown from prototype calibration studies with a proton beam

124

Series Bosch System Development  

Science.gov (United States)

State-of-the-art (SOA) carbon dioxide (CO2) reduction technology for the International Space Station produces methane as a byproduct. This methane is subsequently vented overboard. The associated loss of hydrogen ultimately reduces the mass of oxygen that can be recovered from CO2 in a closed-loop life support system. As an alternative to SOA CO2 reduction technology, NASA is exploring a Series-Bosch system capable of reducing CO2 with hydrogen to form water and solid carbon. This results in 100% theoretical recovery of oxygen from metabolic CO2. In the past, Bosch-based technology did not trade favorably against SOA technology due to a high power demand, low reaction efficiencies, concerns with carbon containment, and large resupply requirements necessary to replace expended catalyst cartridges. An alternative approach to Bosch technology, labeled "Series-Bosch," employs a new system design with optimized multi-stage reactors and a membrane-based separation and recycle capability. Multi-physics modeling of the first stage reactor, along with chemical process modeling of the integrated system, has resulted in a design with potential to trade significantly better than previous Bosch technology. The modeling process and resulting system architecture selection are discussed.

Abney, Morgan B.; Evans, Christopher; Mansell, Matt; Swickrath, Michael

2012-01-01

125

Framework for control system development  

International Nuclear Information System (INIS)

Control systems being developed for the present generation of accelerators will need to adapt to changing machine and operating state conditions. Such systems must also be capable of evolving over the life of the accelerator operation. In this paper we present a framework for the development of adaptive control systems

126

The Guided System Development Framework  

DEFF Research Database (Denmark)

The Service-Oriented Computing paradigm has had significant influence on the Internet. With the emergence of this paradigm, it is important to provide tools that help developers designing and verifying such systems. In this article, we present the Guided System Development (GSD) Framework that aids and guides the developer on the specification of the system being developed, on choosing the appropriate standard protocols suites that achieve the required security properties, on providing an implementation of the specified system, and also on allowing the verification of its security properties.

Carvalho Quaresma, Jose Nuno; Probst, Christian W.

2011-01-01

127

Bone marrow transplantation in patients with storage diseases: a developing country experience / Transplante de medula óssea em pacientes com doença de acúmulo: experiência de um país em desenvolvimento  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese O transplante de medula óssea é uma opção terapêutica para os pacientes com doenças de acúmulo. Entre 1979 e 2002, oito pacientes, quatro femininos e quatro masculinos (entre um e 13 anos de idade) foram submetidos a este procedimento em nosso centro. Seis pacientes apresentavam mucopolissacaridose [...] (MPS I em 3; MPS III em um e MPS VI em 2), um paciente apresentava adrenoleucodistrofia e um apresentava doença de Gaucher. Cinco pacientes receberam o transplante de doador aparentado e três de doador não aparentado. Três pacientes desenvolveram doença do enxerto versus hospedeiro (dois com MPS I e um com MPS VI) e faleceram entre 37 e 151 dias após o transplante. Cinco pacientes sobreviveram entre 4 e 16 anos após o transplante. Três tiveram melhora clínica (um MPS I, um MPS VI e o paciente com doença de Gaucher), um paciente não apresentou progressão da doença (adrenoleucodistrofia) e um paciente não teve alteração da história natural da doença (MPS III). Abstract in english Bone marrow transplantation (BMT) is a therapeutic option for patients with genetic storage diseases. Between 1979 and 2002, eight patients, four females and four males (1 to 13 years old) were submitted to this procedure in our center. Six patients had mucopolysaccharidosis (MPS I in 3; MPS III in [...] one and MPS VI in 2), one had adrenoleukodystrophy (ALD) and one had Gaucher disease. Five patients had related and three unrelated BMT donor. Three patients developed graft versus host disease (two MPS I and one MPS VI) and died between 37 and 151 days after transplantation. Five patients survived 4 to 16 years after transplantation. Three patients improved (one MPS I; one MPS VI and the Gaucher disease patient), one patient had no disease progression (ALD) and in one patient this procedure did not change the natural course of the disease (MPS III).

Marcos C., Lange; Hélio A.G., Teive; André R., Troiano; Marco, Bitencourt; Vaneuza A.M., Funke; Daniela C., Setúbal; José, Zanis Neto; Carlos R., Medeiros; Lineu C., Werneck; Ricardo, Pasquini; Carmen M.S., Bonfim.

128

MPS/CHE Dear Colleague Letter Regarding Proposal Review Changes  

Science.gov (United States)

... journalists with their stories on technical topics; and developing new art forms for communicating ... of our future workforce, and to effective communication with non-specialist audiences. Collectively ...

129

HLW Disposal System Development  

Energy Technology Data Exchange (ETDEWEB)

A KRS is suggested through design requirement analysis of the buffer and the canister which are the constituent of disposal system engineered barrier and HLW management plans are proposed. In the aspect of radionuclide retention capacity, the thickness of the buffer is determined 0.5m, the shape to be disc and ring and the dry density to be 1.6 g/cm{sup 3}. The maximum temperature of the buffer is below 100 .deg. which meets the design requirement. And bentonite blocks with 5 wt% of graphite showed more than 1.0 W/mK of thermal conductivity without the addition of sand. The result of the thermal analysis for proposed double-layered buffer shows that decrease of 7 .deg. C in maximum temperature of the buffer. For the disposal canister, the copper for the outer shell material and cast iron for the inner structure material is recommended considering the results analyzed in terms of performance of the canisters and manufacturability and the geochemical properties of deep groundwater sampled from the research area with granite, salt water intrusion, and the heavy weight of the canister. The results of safety analysis for the canister shows that the criticality for the normal case including uncertainty is the value of 0.816 which meets subcritical condition. Considering nation's 'Basic Plan for Electric Power Demand and Supply' and based on the scenario of disposing CANDU spent fuels in the first phase, the disposal system that the repository will be excavated in eight phases with the construction of the Underground Research Laboratory (URL) beginning in 2020 and commissioning in 2040 until the closure of the repository is proposed. Since there is close correlation between domestic HLW management plans and front-end/back-end fuel cycle plans causing such a great sensitivity of international environment factor, items related to assuring the non-proliferation and observing the international standard are showed to be the influential factor and acceptability of HLW management plans to be the influential factor of making decision for social acceptability of nuclear power.

Choi, J. W.; Choi, H. J.; Lee, J. Y. (and others)

2007-06-15

130

HLW Disposal System Development  

International Nuclear Information System (INIS)

A KRS is suggested through design requirement analysis of the buffer and the canister which are the constituent of disposal system engineered barrier and HLW management plans are proposed. In the aspect of radionuclide retention capacity, the thickness of the buffer is determined 0.5m, the shape to be disc and ring and the dry density to be 1.6 g/cm3. The maximum temperature of the buffer is below 100 .deg. which meets the design requirement. And bentonite blocks with 5 wt% of graphite showed more than 1.0 W/mK of thermal conductivity without the addition of sand. The result of the thermal analysis for proposed double-layered buffer shows that decrease of 7 .deg. C in maximum temperature of the buffer. For the disposal canister, the copper for the outer shell material and cast iron for the inner structure material is recommended considering the results analyzed in terms of performance of the canisters and manufacturability and the geochemical properties of deep groundwater sampled from the research area with granite, salt water intrusion, and the heavy weight of the canister. The results of safety analysis for the canister shows that the criticality for the normal case including uncertainty is the value of 0.816 which meets subcritical condition. Considering nation's 'Basic Plan for Electric Power Demand and Supply' and based on the scenario of disposing CANDU spent fuels in the first phase, the disposal system that the repository will be excavated in eight phases with the construction of the Underground Research Laboratory (URL) beginning in 2020 and commissioning in 2040 until the closure of the repository is proposed. Since there is close correlation between domestic HLW management plans and front-end/back-end fuel cycle plans causing such a great sensitivity of international environment factor, items related to assuring the non-proliferation and observing the international standard are showed to be the influential factor and acceptability of HLW management plans to be the influential factor of making decision for social acceptability of nuclear power

131

Numerical analysis of jet injection mechanism of fuel-coolant interactions using MPS  

International Nuclear Information System (INIS)

The numerical method used in this study is Moving Particle Semi-implicit (MPS) method which is based on moving particles and their interactions. Grids are not necessary, so that large fluid deformation can be calculated without numerical diffusion. To understand the fundamental physics of the jet penetration, water jet injection into a pool of a denser fluid under non-boiling and isothermal conditions is calculated using the MPS method. The density ratio of the denser fluid (Fluorinert) to water is 1.88. The calculation results are compared with experiments which were conducted in the ALPHA/MUSE facility at JAERI. In three-dimensional calculation, the penetration behavior agrees with the experiment. It is found that the jet penetration process is divided to two stages and, at the first stage, the coolant jet can penetrate deeper than existing correlations of breakup length. (author)

132

Preparation of P(DVB-co-MPS) inorganic-organic hybrid polymer microspheres  

Science.gov (United States)

A novel inorganic-organic hybrid polymer microspheres were facilely synthesised by distillation-precipitation polymerization in absence of any stabilizer or surfcant. The process were conducted with [3-(Methacryloyloxy) propyl] trimethoxysilan (MPS) as monomer, divinyl benzene (DVB) as cross linking agent and azobisisobutyronitrile (AIBN) as initator in acetonitrile. A series of silica nanoparticles were prepared in accordance with the volume ratio of MPS, which was varied in the range of 10% to 50%. However, there is no microspheres obtained while the ratio up to 50%. Products were charactered by transmission electron micrograph (TEM) and fourier transform infrared spectroscopy (FTIR). We may infer it from the constructional formular and FTIR graph that there were silicon hydroxyl remained in the microsphere surface.

Wu, Chunrong; Zhang, Jimei; Dai, Zhao; Chen, Xiaoyu

2010-07-01

133

Master Pump Shutdown MPS Software Quality Assurance Plan (SQAP)  

International Nuclear Information System (INIS)

The MPSS Software Quality Assurance (SQAP) describes the tools and strategy used in the development of the MPSS software. The document also describes the methodology for controlling and managing changes to the software

134

Master Pump Shutdown MPS Software Quality Assurance Plan (SQAP)  

Energy Technology Data Exchange (ETDEWEB)

The MPSS Software Quality Assurance (SQAP) describes the tools and strategy used in the development of the MPSS software. The document also describes the methodology for controlling and managing changes to the software.

BEVINS, R.R.

2000-09-20

135

ISE System Development Methodology Manual  

Energy Technology Data Exchange (ETDEWEB)

The Information Systems Engineering (ISE) System Development Methodology Manual (SDM) is a framework of life cycle management guidelines that provide ISE personnel with direction, organization, consistency, and improved communication when developing and maintaining systems. These guide-lines were designed to allow ISE to build and deliver Total Quality products, and to meet the goals and requirements of the US Department of Energy (DOE), Westinghouse Savannah River Company, and Westinghouse Electric Corporation.

Hayhoe, G.F.

1992-02-17

136

An Evaluation of a Novel Instrument for Measuring Macular Pigment Optical Density: the MPS 9000  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Purpose:? Of the antioxidants found in the human retina, only the macular carotenoid quantities can be estimated noninvasively (albeit in a collective fashion), thus facilitating study of their role in that tissue. The aim of this study was to evaluate concordance between macular pigment optical density (MPOD) values recorded on a commercially available instrument, the MPS 9000, with those of an already validated heterochromatic flicker photometry instrument. Also, we assessed and compared ...

Loughman, James; Scanlon, Grainne; Nolan, John M.; O Dwyer, Veronica; Beatty, Stephen

2011-01-01

137

Time evolution analysis of holographic grating on azobenzene polymer films by MPS method  

Science.gov (United States)

The formation of holographic surface relief gratings (SRGs) on azobenzene containing polymers are simulated using the moving particle semi-implicit (MPS) method. The gradient force of optical electric field and the influence of surface tension were considered as the driving forces for mass transport. The particle motions of SRG formation are calculated by giving particles two beams interference with various polarization states. The model for time evolution of SRG formation coincided with experimental results qualitatively.

Barada, Daisuke; Itoh, Masahide; Yatagai, Toyohiko

2004-06-01

138

Analysis of Aurora-A and hMPS1 mitotic kinases in mantle cell lymphoma.  

Science.gov (United States)

Aurora-A and hMPS1 are kinases involved in spindle checkpoint and centrosome duplication regulation and whose alterations have been associated with cell transformation and chromosome instability in different tumor models. In this study, we have examined the possible alterations of these genes in 58 mantle cell lymphomas (MCLs) and 4 MCL-related cell lines. Aurora-A was also examined in 46 diffuse large B-cell lymphomas (DLBCLs). Aurora-A and hMPS1 mRNA expression levels were related to tumor proliferative activity. Interestingly, a MCL case with the highest number or chromosomal imbalances also showed an extremely high value of Aurora-A mRNA expression. No Aurora-A gene amplifications were detected in any tumor or cell line, whereas hemizygous hMPS1 gene deletions were observed in 23% of MCLs and 3 of the 4 cell lines. However, no expression alterations or gene mutations were detected in these cases. The Aurora-A proposed cancer susceptibility polymorphic variant (P31I) was observed with a similar frequency in MCL, DLBCL, chronic lymphocytic leukemia and in the 431 healthy controls. However, the 3 MCLs and 4 DLBCLs with the homozygous variant of this polymorphism had particular clinical characteristics with an unusual early-age presentation and second epithelial malignancies in MCL and extranodal origin in DLBCL. These findings indicate that Aurora-A and hMPS1 aberrations are uncommon in aggressive lymphomas but Aurora-A overexpression may contribute to numerical chromosomal alterations in occasional MCL. Although the Aurora-A P31I polymorphic variant is not directly involved in a genetic predisposition to these lymphomas, it may modulate the clinical presentation of these tumors. PMID:16080195

Camacho, Emma; Beà, Silvia; Salaverría, Itziar; López-Guillermo, Armando; Puig, Xavier; Benavente, Yolanda; de Sanjosé, Silvia; Campo, Elias; Hernández, Luis

2006-01-15

139

Enzyme replacement therapy for Mucopolysaccharidosis Type I among patients followed within the MPS Brazil Network  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english Mucopolysaccharidosis type I (MPS I) is a rare lysosomal disorder caused by deficiency of alph-L-iduronidase. Few clinical trials have assessed the effect of enzyme replacement therapy (ERT) for this condition. We conducted an exploratory, open-label, non-randomized, multicenter cohort study of pati [...] ents with MPS I. Data were collected from questionnaires completed by attending physicians at the time of diagnosis (T1; n = 34) and at a median time of 2.5 years later (T2; n = 24/34). The 24 patients for whom data were available at T2 were allocated into groups: A, no ERT (9 patients; median age at T1 = 36 months; 6 with severe phenotype); B, on ERT (15 patients; median age at T1 = 33 months; 4 with severe phenotype). For all variables in which there was no between-group difference at baseline, a delta of ;±20% was considered clinically relevant. The following clinically relevant differences were identified in group B in T2: lower rates of mortality and reported hospitalization for respiratory infection; lower frequency of hepatosplenomegaly; increased reported rates of obstructive sleep apnea syndrome and hearing loss; and stabilization of gibbus deformity. These changes could be due to the effect of ERT or of other therapies which have also been found more frequently in group B. Our findings suggest MPS I patients on ERT also receive a better overall care. ERT may have a positive effect on respiratory morbidity and overall mortality in patients with MPS I. Additional studies focusing on these outcomes and on other therapies should be performed.

Alícia Dorneles, Dornelles; Louise Lapagesse de Camargo, Pinto; Ana Carolina de, Paula; Carlos Eduardo, Steiner; Charles Marques, Lourenço; Chong Ae, Kim; Dafne Dain Gandelman, Horovitz; Erlane Marques, Ribeiro; Eugênia Ribeiro, Valadares; Isabela, Goulart; Isabel C. Neves de, Souza; João Ivanildo da Costa, Neri; Luiz Carlos, Santana-da-Silva; Luiz Roberto, Silva; Márcia, Ribeiro; Ruy Pires de, Oliveira Sobrinho; Roberto, Giuglianiand; Ida Vanessa Doederlein, Schwartz.

140

Simulation of Taylor bubble flow in T-shaped micro-channel by MPS method  

Science.gov (United States)

Moving Particle Semi-implicit (MPS) method uses particles and their interactions to simulate incompressible flow and it is a promising meshless method for multiphase flow simulation. In order to capture the interface in micro-scale channel, Taylor bubble flow in a T-shaped micro-channel is simulated in this paper. Firstly available surface tension and wettability model are improved and validated by simulating the droplet vibration and static shapes of a droplet attached on the solid surface, respectively. Afterwards, by discretizing the liquid and gas phases into moving particles with different density, bubble slug generation in T-shaped micro-channel is reproduced by MPS method with above models. The good agreement between numerical simulation with visualization experiment confirmed the capacity of MPS for the micro-scale two-phase flow. Finally, bubble generation mechanism is revealed by the velocity field of typical squeezing and shearing regime. The influences of viscosity, surface tension and contact angle on the bubble slug length are also discussed in detail.

Rong, Shaoshan; Chen, Bin

2009-11-01

 
 
 
 
141

Microkernel Development for Embedded Systems  

Directory of Open Access Journals (Sweden)

Full Text Available This paper presents the development of a microkernel with a device driver controller for embedded systems. The implementation was done in C language aiming low cost microcontrollers. The proposed system allowed to perform soft real-time activities while keeping the drivers and the application isolated by a secure layer. The callback system proved itself extremely simple to use while still maintaining the security of the system regarding the temporal constraints.

Rodrigo Maximiano Antunes de Almeida

2013-01-01

142

On the Laplacian model for particle-based simulation using Moving-Particle Semi-implicit (Mps) Method  

Science.gov (United States)

A general form of Laplacian model is derived for the numerical framework of Moving Particle Semi-implicit (MPS) method. The existing proposals of MPS Laplacian model available in the open literature can indeed be reproduced from this general Laplacian model. Most importantly, the numerical accuracy of the evaluated Laplacian term particularly on the irregular particle layout can be further improved by adjusting the tuning parameter introduced in the general Laplacian model.

Ng, Khai-Ching; Sheu, Tony Wen-Hann

2013-12-01

143

Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125.  

Science.gov (United States)

Chromosomal instability can result from defective control of checkpoints and is associated with malignant cell growth. Monopolar spindle 1 (Mps1) is a dual-specificity protein kinase that has important roles in the prevention of aneuploidy during the cell cycle and might therefore be a potential target for new therapeutic agents in the treatment of cancer. To gain insights into the molecular mechanism of Mps1 inhibition by small molecules, we determined the x-ray structure of Mps1, both alone and in complex with the ATP-competitive inhibitor SP600125. Mps1 adopts a classic protein kinase fold, with the inhibitor sitting in the ATP-binding site where it is stabilized by hydrophobic interactions. We identified a secondary pocket, not utilized by SP600125, which might be exploited for the rational design of specific Mps1 inhibitors. These structures provide important insights into the interaction of this protein kinase with small molecules and suggest potential mechanisms for Mps1 regulation. PMID:18480048

Chu, Matthew L H; Chavas, Leonard M G; Douglas, Kenneth T; Eyers, Patrick A; Tabernero, Lydia

2008-08-01

144

Systemic Models of Local Development  

Directory of Open Access Journals (Sweden)

Full Text Available The paper approaches in a systemic manner the topic of local development, attempting, on one hand, to turn into account the previous contributions from the specialized literature and, on the other hand, to emphasize the specific mechanisms, describing and modelling the behavior of a local development system, underlining its feedback. The basic hypotheses of a systemic model for local development are synthesized in emphasizing three main subsystems, representing three levels of public management. At the same time, a local development system is composed by the convergence of two cybernetic systems, namely an administrative and an economic one, each with specific missions. Consequently, the paper aims a model for an economic-administrative system of local development (SEADL, whose self-regulation mechanisms are based on qualitative assessments, concerning the relevance or usefulness/sustainability of a local development policy as well as quantitative assessments, referring to efficiency or effectiveness. In the end of the paper a case study is presented in details, being achieved in Braila Municipality, valorising SEADL feedback, using assessments based on production factors or Keynesian approaches. The study represents only a framework, a general one for approaching a complex topic, such as local development, and it may be obviously completed and improved.

Lucica Matei

2007-01-01

145

Incremental value of 24-hour delayed imaging in 201Tl stress myocardial perfusion studies (MPS) with an 'early rest reinjection' protocol  

International Nuclear Information System (INIS)

Full text: One hundred patients (pts) undergoing stress MPS had 24 h imaging for fixed defects at 4 h delayed imaging. 53 had prior myocardial infarction (MI) and 71 were males. Stress employed isotonic exercise with dipyridamole (0.56 mg kg-1) infusion in 57 pts, exercise alone in 33 and dipyridamole alone in 10. All pts with stress defects had rest-reinjection of 40 MBq of 201Tl after stress imaging had been completed, and most had sublingual nitrate therapy 10 min before reinjection. MPS from the 100 pts (15% of total) were read without clinical data, using a 20 segment scoring system. 51 pts showed -2 segments improvement between 4 and 24 h scores, but 22 pts had shown reversibility between stress and 4 h imaging and the further change did not alter interpretation. The other 29 pts (group A) showed clinically important change in 24 h scores, leaving 71 pts without clinical change (group B). Segmental improvement between 4 and 24 h in group A was 4.62 ± 2.18 and 1.18 ± 1.48 in group B (P = 0.02). Group A stress defect scores were not greater (10.90 ± 3.60) or more severe (3.72 ± 3.06) than in group B (8.92 ± 4.34 and 2.79 ± 3.11); 18 group A pts had MI compared with 38 group B pts. No significant correlation was found between improved 4-24 h scores and parameters of stress-LV dysfunction. There is benefit from 24 h, 201TI MPS in patients with persisting 4 h defects, despite early rest-reinjection and acute nitrate therapyction and acute nitrate therapy

146

Developing an Environmental Scanning System.  

Science.gov (United States)

A step-by-step approach is provided for developing an environmental scanning system for colleges and universities to assist them in planning for the future. The objectives of such a system are to detect social, scientific, economic, technical, and political interactions important to the organization; define potential threats and opportunities from…

Morrison, James L.

147

TOPEX electrical power system  

Science.gov (United States)

The TOPEX mission requirements which impact the power requirements and analyses are presented. A description of the electrical power system (EPS), including energy management and battery charging methods that were conceived and developed to meet the identified satellite requirements, is included. Analysis of the TOPEX EPS confirms that all of its electrical performance and reliability requirements have been met. The TOPEX EPS employs the flight-proven modular power system (MPS) which is part of the Multimission Modular Spacecraft and provides high reliability, abbreviated development effort and schedule, and low cost. An energy balance equation, unique to TOPEX, has been derived to confirm that the batteries will be completely recharged following each eclipse, under worst-case conditions. TOPEX uses three NASA Standard 50AH Ni-Cd batteries, each with 22 cells in series. The MPS contains battery charge control and protection based on measurements of battery currents, voltages, temperatures, and computed depth-of-discharge. In case of impending battery depletion, the MPS automatically implements load shedding.

Chetty, P. R. K.; Roufberg, Lew; Costogue, Ernest

1991-01-01

148

Development of the accelerating system  

Energy Technology Data Exchange (ETDEWEB)

One of the main purposes of the 'Development of the Accelerating System' is developing a 100-MeV proton linac which accelerate proton beams from 20 MeV to 100 MeV by using 7 DTL (drift tube linac) tanks. Two of them were finished in the 2-nd stage of the project. The remaining part was also successfully fabricated and installed at Gyeongju site of KAERI. The MEBT is an essential component to extract and supply 20-MeV proton beams to users, and to match proton beams to the next accelerating structure for 100-MeV acceleration. The development of the MEBT has successfully finished. The project also developed the digital LLRF (low level RF) system which control the accelerating field within 1% in magnitude and 1 degree in phase. This system has been successfully tested in the 20-MeV linac operation at Daejeon site of KAERI. The modified version of the digital LLRF system will be used in the 100-MeV linac operation. The project also developed the beam diagnostic system. They are the strip-line type beam position monitor (BPM), the beam current monitor (CT), the beam loss monitor (BLM), and the emittance measurement system. They are used to measure the characteristics of the 20-MeV proton beams. The project also developed the EPIC-based control system. It is used to monitor the status of the accelerator and components, and to remotely control accelerator components. It has been used and modified in the 20-MeV linac operation. The modified version of the LLRF, diagnostics and control systems will be used in 100-MeV linac operation.

Jang, Jiho; Kwon, H. J.; Kim, D. I.; Kim, H. S.; Ryu, J. Y.; Park, B. S.; Seol, K. T.; Yun, S. P.; Song, Y. G.; Cho, Y. S.

2013-02-15

149

Pathogenesis of Morquio A syndrome: an autopsied case reveals systemic storage disorder.  

Science.gov (United States)

Mucopolysaccharidosis IVA (MPS IVA; Morquio A syndrome) is a lysosomal storage disorder caused by deficiency of N-acetylgalactosamine-6-sulfate sulfatase, which results in systemic accumulation of glycosaminoglycans (GAGs), keratan sulfate and chondroitin-6-sulfate. Accumulation of these GAGs causes characteristic features as disproportionate dwarfism associated with skeletal deformities, genu valgum, pigeon chest, joint laxity, and kyphoscoliosis. However, the pathological mechanism of systemic skeletal dysplasia and involvement of other tissues remain unanswered in the paucity of availability of an autopsied case and successive systemic analyses of multiple tissues. We report here a 20-year-old male autopsied case with MPS IVA, who developed characteristic skeletal features by the age of 1.5 years and died of acute respiratory distress syndrome five days later after occipito-C1-C2 cervical fusion. We pathohistologically analyzed postmortem tissues including trachea, lung, thyroid, humerus, aorta, heart, liver, spleen, kidney, testes, bone marrow, and lumbar vertebrae. The postmortem tissues relevant with clinical findings demonstrated 1) systemic storage materials in multiple tissues beyond cartilage, 2) severely vacuolated and ballooned chondrocytes in trachea, humerus, vertebrae, and thyroid cartilage with disorganized extracellular matrix and poor ossification, 3) appearance of foam cells and macrophages in lung, aorta, heart valves, heart muscle, trachea, visceral organs, and bone marrow, and 4) storage of chondrotin-6-sulfate in aorta. This is the first autopsied case with MPS IVA whose multiple tissues have been analyzed pathohistologically and these pathological findings should provide a new insight into pathogenesis of MPS IVA. PMID:23683769

Yasuda, Eriko; Fushimi, Kazunari; Suzuki, Yasuyuki; Shimizu, Katsuji; Takami, Tsuyoshi; Zustin, Jozef; Patel, Pravin; Ruhnke, Kristen; Shimada, Tsutomu; Boyce, Bobbie; Kokas, Terry; Barone, Carol; Theroux, Mary; Mackenzie, William; Nagel, Barbara; Ryerse, Jan S; Orii, Kenji E; Iida, Hiroki; Orii, Tadao; Tomatsu, Shunji

2013-07-01

150

Characterization of a putative spindle assembly checkpoint kinase Mps1, suggests its involvement in cell division, morphogenesis and oxidative stress tolerance in Candida albicans.  

Science.gov (United States)

In Saccharomyces cerevisiae MPS1 is one of the major protein kinase that governs the spindle checkpoint pathway. The S. cerevisiae structural homolog of opportunistic pathogen Candida albicans CaMPS1, is indispensable for the cell viability. The essentiality of Mps1 was confirmed by Homozygote Trisome test. To determine its biological function in this pathogen conditional mutant was generated through regulatable MET3 promoter. Examination of heterozygous and conditional (+Met/Cys) mps1 mutants revealed a mitosis specific arrest phenotype, where mutants showed large buds with undivided nuclei. Flowcytometry analysis revealed abnormal ploidy levels in mps1 mutant. In presence of anti-microtubule drug Nocodazole, mps1 mutant showed a dramatic loss of viability suggesting a role of Mps1 in Spindle Assembly Checkpoint (SAC) activation. These mutants were also defective in microtubule organization. Moreover, heterozygous mutant showed defective in-vitro yeast to hyphae morphological transition. Growth defect in heterozygous mutant suggest haploinsufficiency of this gene. qRT PCR analysis showed around 3 fold upregulation of MPS1 in presence of serum. This expression of MPS1 is dependent on Efg1 and is independent of other hyphal regulators like Ras1 and Tpk2. Furthermore, mps1 mutants were also sensitive to oxidative stress. Heterozygous mps1 mutant did not undergo morphological transition and showed 5-Fold reduction in colony forming units in response to macrophage. Thus, the vital checkpoint kinase, Mps1 besides cell division also has a role in morphogenesis and oxidative stress tolerance, in this pathogenic fungus. PMID:25025778

Kamthan, Mohan; Nalla, Vijaya Kumar; Ruhela, Deepa; Kamthan, Ayushi; Maiti, Protiti; Datta, Asis

2014-01-01

151

The safety of dipyridamole myocardial perfusion scintigraphy (MPS) in patients with end-stage chronic airways limitations (CAL)  

International Nuclear Information System (INIS)

Full text: Dipyridamole MPS is a well-established investigative technique in the diagnosis and pre-operative risk stratification of patients with possible coronary artery disease. However, there remains a concern of its use in patients with end-stage chronic airways limitations (CAL). Lung volume reduction surgery (LVRS) is a recent therapeutic option for such patients. The options for non-invasive pre-operative cardiac assessment in such patients are limited. This study reviewed the safety of dipyridamole use in such a clinical setting. 20 patients (10M, 10F, mean age 64.8 yrs) were evaluated. None had any history of ischaemic heart disease. Dipyridamole was administered intravenously at a dose of 0.05 mg/kg. Six patients remained asymptomatic throughout the procedure, while none experienced any chest pain. Two patients experienced moderate dyspnoea, which was rapidly relieved with aminophylline (100mg IV) during the recovery phase of the study. Two others developed mild dyspnoea; one settled spontaneously, while the other responded promptly to aminophylline. Aminophylline was administered to nine other patients to reverse minor symptoms (headache, flushing sensation). One other patient developed marked hypotension (SBP fell >20mmHg) and bradycardia, but no ECG changes for myocardial ischaemia. He responded well to aminophylline. His myocardial perfusion scan demonstrated extensive reversible myocardial ischaemia. Although the population size was small, dipyridamole appears safe to use in patients with end-stage CAL. Copyright (2000) The Australian and New Zealand Society of Nuclear Medicine Inc

152

Open quantum systems recent developments  

CERN Document Server

Understanding dissipative dynamics of open quantum systems remains a challenge in mathematical physics. This problem is relevant in various areas of fundamental and applied physics. From a mathematical point of view, it involves a large body of knowledge. Significant progress in the understanding of such systems has been made during the last decade. These books present in a self-contained way the mathematical theories involved in the modeling of such phenomena. They describe physically relevant models, develop their mathematical analysis and derive their physical implications. In Volume I the Hamiltonian description of quantum open systems is discussed. This includes an introduction to quantum statistical mechanics and its operator algebraic formulation, modular theory, spectral analysis and their applications to quantum dynamical systems. Volume II is dedicated to the Markovian formalism of classical and quantum open systems. A complete exposition of noise theory, Markov processes and stochastic differential...

Joye, Alain; Pillet, Claude-Alain

2006-01-01

153

Heating Systems Course Development Model  

Science.gov (United States)

The Advanced Technology Environmental and Energy Center (ATEEC) has provided this course development model on heating systems, including gas, fuel oil, and electric furnaces, and heat pumps. Energy conservation, efficiency options and environmental impacts are also covered. Users must download this resource for viewing, which requires a free log-in. There is no cost to download the item.

2011-05-18

154

Development of safeguards system simulator  

International Nuclear Information System (INIS)

Due to a large plutonium (Pu) throughput and high burn-up fuel in an advanced reprocessing plant, we have the responsibility to undertake the inevitable burden of nuclear material accountancy (NMA) to meet the International Atomic Energy Agency (IAEA) safeguards criteria. A large amount of sampling analysis and inspectors' activities result in a great cost in facility operation to verify no concealment and undeclared use of Pu. In addition to NMA, containment and surveillance (C/S), process monitoring (PM), and curium (Cm) balance have been used for the safeguards activities to complement NMA. However, except for NMA, any mathematical or regulatory formalism in the safeguards measures have not been presented so far, therefore it is difficult to evaluate the cost-effective performance of the safeguards system. In order to design an advanced safeguards system for the fast reactor fuel cycle, the JAEA has started to develop a safeguards system simulator. A NMA core in the simulator is composed of a near-real-time accounting (NRTA) code which had been already developed and applied to investigate the NMA characteristics of JAEA facilities. A 'multivariate and multi-scale core' is based on a multivariate mathematical analysis combined with a multi-scale statistical process analysis making use of a wavelet decomposition forms safeguards envelope, which provides a control and monitoring system logic. Multi-scale principle component analysis of the core had been applied to 'material unaccounted for' (MUF). A concept of multiple optimization core is proposed as the safeguards formalism, with probabilistic risk analysis and cost-performance characteristics of the safeguards system, is discussed in the presentation. Flow meter and non-destructive analysis can be more broadly applied to the system in a cost-effective manner. A virtual design and objective-driven model will be developed in the simulator in the future to support an effective safeguards design and to develop a walk-through' virtual plant model. (author)

155

Development of teleoperated cleanup system  

International Nuclear Information System (INIS)

This report describes the development of a teleoperated cleanup system for use in a highly radioactive environment of DFDF(DUPIC Fuel Demonstration Facility) at KAERI where direct human access to the in-cell is strictly limited. The teleoperated cleanup system was designed to remotely remove contaminants placed or fixed on the floor surface of the hot-cell by mopping them with wet cloth. This cleanup system consists of a mopping slave, a mopping master and a control console. The mopping slave located at the in-cell comprises a mopping tool with a mopping cloth and a mobile platform, which were constructed in modules to facilitate maintenance. The mopping master that is an input device to control the mopping slave has kinematic dissimilarity with the mopping slave. The control console provides a means of bilateral control flows and communications between the mopping master and the mopping slave. In operation, the human operator from the out-of-cell performs a series of decontamination tasks remotely by manipulating the mopping slave located in-cell via a mopping master, having a sense of real mopping. The environmental and mechanical design considerations, and control systems of the developed teleoperated cleanup system are also described

156

Pressure oscillation reduction in RSM by means of a passive control system  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Scope of the present research is to develop a passive control system to be applied in a full scale bench firing test of ARIANE 5 MPS P230. All the activities related to the development as such a passive control system, from thedefinition of its requirements and the choice of the technology, to its design and its application of a full scale bench firing test, are the object of the present research program.

Telara, Marco

2006-01-01

157

Distinct modulated pupil function system for real-time imaging of living cells.  

Science.gov (United States)

Optical microscopy is one of the most contributive tools for cell biology in the past decades. Many microscopic techniques with various functions have been developed to date, i.e., phase contrast microscopy, differential interference contrast (DIC) microscopy, confocal microscopy, two photon microscopy, superresolution microscopy, etc. However, person who is in charge of an experiment has to select one of the several microscopic techniques to achieve an experimental goal, which makes the biological assay time-consuming and expensive. To solve this problem, we have developed a microscopic system with various functions in one instrument based on the optical Fourier transformation with a lens system for detection while focusing on applicability and user-friendliness for biology. The present instrument can arbitrarily modulate the pupil function with a micro mirror array on the Fourier plane of the optical pathway for detection. We named the present instrument DiMPS (Distinct optical Modulated Pupil function System). The DiMPS is compatible with conventional fluorescent probes and illumination equipment, and gives us a Fourier-filtered image, a pseudo-relief image, and a deep focus depth. Furthermore, DiMPS achieved a resolution enhancement (pseudo-superresolution) of 110 nm through the subtraction of two images whose pupil functions are independently modulated. In maximum, the spatial and temporal resolution was improved to 120 nm and 2 ms, respectively. Since the DiMPS is based on relay optics, it can be easily combined with another microscopic instrument such as confocal microscope, and provides a method for multi-color pseudo-superresolution. Thus, the DiMPS shows great promise as a flexible optical microscopy technique in biological research fields. PMID:22962597

Watanabe, Tomonobu M; Tsukasaki, Yoshikazu; Fujita, Hideaki; Ichimura, Taro; Saitoh, Tatsuya; Akira, Shizuo; Yanagida, Toshio

2012-01-01

158

STUDI DAYA HAMBAT IN VITRO ANTI MPS ECTO CIK (MAYOR PHYSIOLOGICAL PROTEIN SUBSTRAT TERHADAP VIABILITAS SPERMATOZOA KAMBING DAN DOMBA  

Directory of Open Access Journals (Sweden)

Full Text Available Untuk menuju suatu penemuan tentang vaksin kontrasepsi bagi pria, diperlukan penelitian dasar mengenai hal tersebut. Sebagai langkah awal dilakukan uji hambatan Anti MPS ecto CIK terhadap viabilitas spermatozoa kambing dan domba, sedangkan dari penelitian pendahuluan diketahui bahwa anti MPS dari ecto-CIK ini mampu bereaksi silang dengan spermatozoa domba, dan sapi. Berdasarkan hal tersebut peneliti tertarik untuk mengetahui seberapa besar peranan anti MPS ecto CIK dalam menghambat viabilitas spermatozoa kambing dan domba secara in vitro.Tujuan dari penelitian ini adalah mengetahui seberapa besar peranan anti MPS ecto CIK dengan pemberian perlakuan konsentrasi dan lama inkubasi serta interaksi kedua perlakuan dalam menghambat viabilitas spermatozoa kambing dan domba. Rancangan penelitian yang digunakan adalah rancangan acak lengkap (RAL dengan pola faktorial yang terdiri atas 2 faktor utama, faktor pertama yaitu: dosis pengenceran, 0µl, 5µl, 10µl, dan 15µl, dan faktor kedua yaitu: lama inkubasi, yaitu 5 menit, 30 menit, 60 menit, dan 120 menit, masing-masing 6 kali ulangan. Data viabilitas spermatozoa kambing dan domba dianalisis dengan Uji one way ANOVA, jika hasil dari analisis tersebut terdapat pengaruh yang nyata maka akan dilanjutkan dengan Uji Jarak Berganda Duncan dengan taraf signifikansi 5% (0,05.Pemberian perlakuan anti MPS dari ecto CIK membran spermatozoa kambing dengan konsentrasi dan 0 µl, 5 µl, 10 µl, 15 µl dan lama inkubasi 5 menit, 30 menit, 60 menit dan 120 menit berpengaruh signifikan dalam menghambat viabilitas spermatozoa kambing dan domba. Pada perlakuan anti MPS ecto CIK dengan konsentrasi 15 µl dan lama inkubasi 120 menit merupakan perlakuan yang paling optimal dalam menghambat viabilitas spermatozoa kambing (45,50 ± 11,16%; 44,87 ± 9,40% dan domba (55,54 ± 18,87%; 40,58 ± 13,20%. Interaksi pemberian perlakuan konsentrasi dan lama inkubasi anti MPS ecto CIK pada konsentrasi 15 µl dan lama inkubasi 120 menit anti MPS ecto CIK paling berpengaruh dalam menghambat viabilitas spermatozoa domba (26,83 ± 8,70%, sedangkan pada kambing tidak berpengaruh.

Bayyinatul Muchtaromah

2009-03-01

159

Development of logistics information systems  

Directory of Open Access Journals (Sweden)

Full Text Available An adequate logistics information system provides real time automated data processing, distribution and of information according to Terrain Commander's requirements, which leads to timely fulfillment of logistic demands of units. SAP ERP The SAP ERP application is the integrated (ERP software capable of working with complex organisational structures, personnel, equipment, and finance. It enables planning and combining forces for every type of operations. The system also enables the determination of the readiness status of modelled forces. ISL The Information System for Logistics (ISL is a comprehensive information system of the Ministry of Defence (MoD and the Army of the Czech Republic that covers many areas: acquisition, supply, ammunition and equipment maintenance, logistics, etc. The ISL provides support for military logistics in all important areas of consumer and acquisition logistics, satisfaying all kinds of Defence Forces needs in the country and abroad. LOGFAS The information system LOGFAS comprises Logistics Database (LOGBASE, Movement and Transportation software (M&T, Allied Command Europe Resource Optimisation Software System (ACROSS and Logistic Reporting System (LOGREP. The Logistics Database LOGBASE represents a logistics information source and also a database related to assets, forces, geography, infrastructure, targets, supplies, movements and medical data. The main software tools which rely on the LOGBASE are M&T, ACROSS and LOGREP. GCSS-Army The original impetus to create the SALE came in the mid-90s when the United States Department of Defense (DoD started a logistics modernisation programme. One of tasks was to build The Single Army Logistics Enterprise (SALE for the purpose of covering the whole organisational structure of the DoD. There are three components of the SALE: GCSS-Army, PLM+ and LMP. Each of them uses the commercial Enterprise Resource Planning SAP Software with a Web access. The main component, GCSS-Army (Global Combat Support System-Army Field/Tactical, is intended for the tactical level and it will replace 14 tactical logistics information systems and connect them with the rest of the information environment. Tendencies in the development of logistics information systems In line with the presented information solutions, it is possible to extract relevant conclusions about tendencies in the development of these types of systems all around the world. These conclusions should be implemented, through adequate principles, into domestic software development. Three main tendencies are visible in modern solutions: using centralised databases, integration of existing separated software solutions, and connecting previously autonomus systems. Conclusion In accordance with present time requirements, logistic support should be realised as close as possible to the origin of a logistic need, in real time and adequately. Information systems enable real time delivery of information needed for a quality logistic support in all phases of operations as well as for a faster generation of all types of documents.

Milan Ž. Dronjak

2012-10-01

160

Reciprocating Feed System Development Status  

Science.gov (United States)

The reciprocating feed system (RFS) is an alternative means of providing high pressure propellant flow at low cost and system mass, with high fail-operational reliability. The RFS functions by storing the liquid propellants in large, low-pressure tanks and then expelling each propellant through two or three small, high-pressure tanks. Each RFS tank is sequentially filled, pressurized, expelled, vented, and refilled so as to provide a constant, or variable, mass flow rate to the engine. This type of system is much lighter than a conventional pressure fed system in part due to the greatly reduced amount of inert tank weight. The delivered payload for an RFS is superior to that of conventional pressure fed systems for conditions of high total impulse and it is competitive with turbopump systems, up to approximately 2000 psi. An advanced version of the RFS uses autogenous pressurization and thrust augmentation to achieve higher performance. In this version, the pressurization gases are combusted in a small engine, thus making the pressurization system, in effect, part of the propulsion system. The RFS appears to be much less expensive than a turbopump system, due to reduced research and development cost and hardware cost, since it is basically composed of small high- pressure tanks, a pressurization system, and control valves. A major benefit is the high reliability fail-operational mode; in the event of a failure in one of the three tank-systems, it can operate on the two remaining tanks. Other benefits include variable pressure and flow rates, ease of engine restart in micro-gravity, and enhanced propellant acquisition and control under adverse acceleration conditions. We present a system mass analysis tool that accepts user inputs for various design and mission parameters and calculates such output values payload and vehicle weights for the conventional pressure fed system, the RFS, the Autogenous Pressurization Thrust Augmentation (APTA) RFS, and turbopump systems. Using this tool, a preliminary design of a representative crew exploration vehicle (CEV) has been considered. The design parameters selected for a representative system were modeled after the orbital maneuvering system (OMS) on the Shuttle Orbiter, with an increase of roughly a factor of ten in the delta- V capability and a greater thrust (30,000 lbs, vs. 12,000 lbs). Both storable and cryogenic propellants were considered. Results show that a RFS is a low mass alternative to conventional pressure fed systems, with a substantial increase in payload capability and that it is weight-competitive with turbopump systems at low engine pressure (a few hundred psi); at high engine pressures, the APTA RFS appears to offer the highest payload. We also present the status of the RFS test bed fabrication, assembly, and checkout. This test bed is designed to provide flow rates appropriate for engines in the roughly 10,000 to 30,000 lb thrust range.

Trewek, Mary (Technical Monitor); Blackmon, James B.; Eddleman, David E.

2005-01-01

 
 
 
 
161

KSTAR RF heating system development  

International Nuclear Information System (INIS)

Design, high-voltage test, and installation of 6 MW ICRF heating system for KSTAR is completed. The antenna demonstrated satisfactory standoff at high voltages up to 41 kV for 300 sec. The result indicates good power handling capabilities of the antenna as high as 10 MW/m2. This power density is equivalent to RF power coupling of 6 MW into a 4 ?/m target plasma, and is typical of advanced tokamak heating scenarios. In addition, vacuum feed through, DC break, and liquid stub developed for 300 sec operation are installed, as well as a 2 MW, 30-60MHz transmitter. The transmitter successfully produced output powers of 600 kW continuously, 1.5?1.8 MW for 300 sec, and 2 MW for 100 msec or shorter pulses. A realtime control system based on DSP and EPICS is developed, installed, and tested on the ICRF system. Initial results from feasibility study indicate that the present antenna and the transmission lines could allow load-resilient operation on KSTAR. Until the KSTAR tokamak start to produce plasmas in 2008, however, hands-on operational experiences are obtained from participating in ICRF heating experiments at ASDEX and DIII-D tokamaks arranged through international cooperation

162

Expert system development (ESD) shell  

International Nuclear Information System (INIS)

An Expert System Development (ESD) Shell design implementation is desribed in detail. The shell provides high-level generic facilities for Knowledge Representation (KR) and inferencing and tools for developing user interfaces. Powerful set of tools in the shell relieves much of the programming burden in the ES development. The shell is written in PROLOG under IBM PC/AT. KR facilities are based on two very powerful formalisms namely, frames and rules. Inference Engine (IE) draws most of its power from unification and backward reasoning strategy in PROLOG. This basic mechanism is enhanced further by incorporating both forward and backward chaining of rules and frame-based inferencing. Overall programming style integrates multiple paradigms including logic, object oriented, access-oriented and imperative programming. This permits ES designer a lot of flexibility in organizing inference control. Creation and maintainance of knowledge base is a major activity. The shell, therefore, provides number of facilities to simplify these tasks. Shell design also takes note of the fact that final success of any system depends on end-user satisfaction and hence provides features to build use-friendly interfaces. The shell also provides a set of interfacing predicates so that it can be embedded within any PROLOG program to incorporate functionalilty of the shell in the user program. (author). 10 refs., 8 figs

163

Structure-based design of orally bioavailable 1H-pyrrolo[3,2-c]pyridine inhibitors of mitotic kinase monopolar spindle 1 (MPS1).  

Science.gov (United States)

The protein kinase MPS1 is a crucial component of the spindle assembly checkpoint signal and is aberrantly overexpressed in many human cancers. MPS1 is one of the top 25 genes overexpressed in tumors with chromosomal instability and aneuploidy. PTEN-deficient breast tumor cells are particularly dependent upon MPS1 for their survival, making it a target of significant interest in oncology. We report the discovery and optimization of potent and selective MPS1 inhibitors based on the 1H-pyrrolo[3,2-c]pyridine scaffold, guided by structure-based design and cellular characterization of MPS1 inhibition, leading to 65 (CCT251455). This potent and selective chemical tool stabilizes an inactive conformation of MPS1 with the activation loop ordered in a manner incompatible with ATP and substrate-peptide binding; it displays a favorable oral pharmacokinetic profile, shows dose-dependent inhibition of MPS1 in an HCT116 human tumor xenograft model, and is an attractive tool compound to elucidate further the therapeutic potential of MPS1 inhibition. PMID:24256217

Naud, Sébastien; Westwood, Isaac M; Faisal, Amir; Sheldrake, Peter; Bavetsias, Vassilios; Atrash, Butrus; Cheung, Kwai-Ming J; Liu, Manjuan; Hayes, Angela; Schmitt, Jessica; Wood, Amy; Choi, Vanessa; Boxall, Kathy; Mak, Grace; Gurden, Mark; Valenti, Melanie; de Haven Brandon, Alexis; Henley, Alan; Baker, Ross; McAndrew, Craig; Matijssen, Berry; Burke, Rosemary; Hoelder, Swen; Eccles, Suzanne A; Raynaud, Florence I; Linardopoulos, Spiros; van Montfort, Rob L M; Blagg, Julian

2013-12-27

164

Computer aided training system development  

International Nuclear Information System (INIS)

The first three phases of Training System Development (TSD) -- job and task analysis, curriculum design, and training material development -- are time consuming and labor intensive. The use of personal computers with a combination of commercial and custom-designed software resulted in a significant reduction in the man-hours required to complete these phases for a Health Physics Technician Training Program at a nuclear power station. This paper reports that each step in the training program project involved the use of personal computers: job survey data were compiled with a statistical package, task analysis was performed with custom software designed to interface with a commercial database management program. Job Performance Measures (tests) were generated by a custom program from data in the task analysis database, and training materials were drafted, edited, and produced using commercial word processing software

165

Computational Aeroacoustic Analysis System Development  

Science.gov (United States)

Many industrial and commercial products operate in a dynamic flow environment and the aerodynamically generated noise has become a very important factor in the design of these products. In light of the importance in characterizing this dynamic environment, Rocketdyne has initiated a multiyear effort to develop an advanced general-purpose Computational Aeroacoustic Analysis System (CAAS) to address these issues. This system will provide a high fidelity predictive capability for aeroacoustic design and analysis. The numerical platform is able to provide high temporal and spatial accuracy that is required for aeroacoustic calculations through the development of a high order spectral element numerical algorithm. The analysis system is integrated with well-established CAE tools, such as a graphical user interface (GUI) through PATRAN, to provide cost-effective access to all of the necessary tools. These include preprocessing (geometry import, grid generation and boundary condition specification), code set up (problem specification, user parameter definition, etc.), and postprocessing. The purpose of the present paper is to assess the feasibility of such a system and to demonstrate the efficiency and accuracy of the numerical algorithm through numerical examples. Computations of vortex shedding noise were carried out in the context of a two-dimensional low Mach number turbulent flow past a square cylinder. The computational aeroacoustic approach that is used in CAAS relies on coupling a base flow solver to the acoustic solver throughout a computational cycle. The unsteady fluid motion, which is responsible for both the generation and propagation of acoustic waves, is calculated using a high order flow solver. The results of the flow field are then passed to the acoustic solver through an interpolator to map the field values into the acoustic grid. The acoustic field, which is governed by the linearized Euler equations, is then calculated using the flow results computed from the flow solver.

Hadid, A.; Lin, W.; Ascoli, E.; Barson, S.; Sindir, M.

2001-01-01

166

AGING SYSTEM DESIGN DEVELOPMENT STRATEGY  

International Nuclear Information System (INIS)

This plan provides an overview, work to date, and the path forward for the design development strategy of the Aging cask for aging commercial spent nuclear fuel (CSNF) at the Yucca Mountain Project (YMP) repository site. Waste for subsurface emplacement at the repository includes US Department of Energy (DOE) high-level radioactive waste (HLW), DOE SNF, commercial fuel in dual-purpose canisters (DPCs), uncanistered bare fuel, naval fuel, and other waste types. Table 1-1 lists the types of radioactive materials that may be aged at YMP, and those materials that will not be placed in an aging cask or module. This plan presents the strategy for design development of the Aging system. The Aging system will not handle naval fuel, DOE HLW, MCOs, or DOE SNF since those materials will be delivered to the repository in a state and sequence that allows them to be placed into waste packages for emplacement. Some CSNF from nuclear reactors, especially CSNF that is thermally too hot for emplacement underground, will need to be aged at the repository

167

Social networks, politics and Commitment 2.0: Spanish MPs on Facebook  

Directory of Open Access Journals (Sweden)

Full Text Available In a technologically and sociologically advanced society, the organizations that do not use the new media and the cyber communication techniques are probably doomed to failure. In this virtual sphere the social networks constitute a suitable resource and channel for the implementation of political marketing 2.0, as it provides a scenario where the interaction with users is possible. From this perspective, we verified their presence of the 350 members of the Spanish Congress on Facebook, the country’s most popular social network, in order to establish the predominant typologies, updating frequency, contents, resources, and the types of information posted in this spaces.This article also examines the interactivity of MPs in what we have termed Commitment 2.0: political communication in personal contexts such as social networks requires going from the participatory attitude to the participatory action; that is, to accept the interaction 2.0 as the correct behaviour on the network.

José Sixto, B.A.

2011-01-01

168

The Micro-Pillar Shear-Stress Sensor MPS3 for Turbulent Flow  

Directory of Open Access Journals (Sweden)

Full Text Available Wall-shear stress results from the relative motion of a fluid over a body surface as a consequence of the no-slip condition of the fluid in the vicinity of the wall. To determine the two-dimensional wall-shear stress distribution is of utter importance in theoretical and applied turbulence research. In this article, characteristics of the Micro-Pillar Shear-Stress Sensor MPS3, which has been shown to offer the potential to measure the two-directional dynamic wall-shear stress distribution in turbulent flows, will be summarized. After a brief general description of the sensor concept, material characteristics, possible sensor-structure related error sources, various sensitivity and distinct sensor performance aspects will be addressed. Especially, pressure-sensitivity related aspects will be discussed. This discussion will serve as ‘design rules’ for possible new fields of applications of the sensor technology.

Sebastian Große

2009-03-01

169

Development of vertical lift systems  

Energy Technology Data Exchange (ETDEWEB)

A description is presented of development of vertical mining shaft transport in KOMAG (Design and technology center for mining equipment) in Poland: 1) pitting hoisting equipment (power - up to 500 kW, manuf. by ZGODA; 2) driving hoist equipment (development proceeded from the first pieces of equipment for open pit operations, such as type VV-3000 models, 290 and 400 kW to machines like VOV-5500 at 630 kW, to modern machines like V-5000 with 2x1000 kW, including export models; in the near future 2400 kW model V 4500 machines without reductors will be use, having a thyristor transformer/direct current motor; 3) underground hoist units that are explosion-safe (the most recent model - 2-33000 MH with a haulage of 60 kH, 2x80 kW, manuf. by RYFAMA plant); 4) mine shaft hoist machinery with asynchronous feed (power range - from 500 to 2000 kW; two-cable and four-cable hoist models have been built - WL 2/4500/2x630 and WL 4/3200/2x630; new dynamic braking systems have been developed; also ones with electro-pneumatic regulators that provide smoothness in changes of the braking torque; 5) control and safety devices for the hoist machinery (including programs controlling runs of hoist equipment, automatic control devices for cable slippage along the pulleys, and controls for ''pull-up'' of the hoist vessel; 6) speciasl lift devices - model V-1500A and V-1100A for carrying out inspections and maintenance operations in shafts; 7) auxiliary devices for performing transport and loading operations in the shaft area. Important directions in KOMAG research include optimization of kinematic parameters and dynamics of mining hoist systems, standardization of elevator machinery and studying their reliability.

Zmyslowski, T.

1980-01-01

170

Gradual Progress Found in MPS Reform Initiative: Third in a Series. Research Brief, Volume 91, Number 5. June 12, 2003  

Science.gov (United States)

The Milwaukee Public Schools (MPS) Neighborhood Schools Initiative (NSI) appears to be making incremental progress towards its twin goals of increasing neighborhood capacity and reducing busing, although results are mixed in this 2002-2003 report, the third year of NSI implementation. Reported findings include: (1) Thirty-nine percent of all…

Public Policy Forum, 2003

2003-01-01

171

Space Launch System Development Status  

Science.gov (United States)

Development of NASA's Space Launch System (SLS) heavy lift rocket is shifting from the formulation phase into the implementation phase in 2014, a little more than three years after formal program approval. Current development is focused on delivering a vehicle capable of launching 70 metric tons (t) into low Earth orbit. This "Block 1" configuration will launch the Orion Multi-Purpose Crew Vehicle (MPCV) on its first autonomous flight beyond the Moon and back in December 2017, followed by its first crewed flight in 2021. SLS can evolve to a130-t lift capability and serve as a baseline for numerous robotic and human missions ranging from a Mars sample return to delivering the first astronauts to explore another planet. Benefits associated with its unprecedented mass and volume include reduced trip times and simplified payload design. Every SLS element achieved significant, tangible progress over the past year. Among the Program's many accomplishments are: manufacture of Core Stage test panels; testing of Solid Rocket Booster development hardware including thrust vector controls and avionics; planning for testing the RS-25 Core Stage engine; and more than 4,000 wind tunnel runs to refine vehicle configuration, trajectory, and guidance. The Program shipped its first flight hardware - the Multi-Purpose Crew Vehicle Stage Adapter (MSA) - to the United Launch Alliance for integration with the Delta IV heavy rocket that will launch an Orion test article in 2014 from NASA's Kennedy Space Center. Objectives of this Earth-orbit flight include validating the performance of Orion's heat shield and the MSA design, which will be manufactured again for SLS missions to deep space. The Program successfully completed Preliminary Design Review in 2013 and Key Decision Point C in early 2014. NASA has authorized the Program to move forward to Critical Design Review, scheduled for 2015 and a December 2017 first launch. The Program's success to date is due to prudent use of proven technology, infrastructure, and workforce from the Saturn and Space Shuttle programs, a streamlined management approach, and judicious use of new technologies. The result is a safe, affordable, sustainable, and evolutionary path to development of an unprecedented capability for future missions across the solar system. In an environment of economic challenges, the nationwide SLS team continues to meet ambitious budget and schedule targets. This paper will discuss SLS program and technical accomplishments over the past year and provide a look at the milestones and challenges ahead.

Lyles, Garry

2014-01-01

172

MEASUREMENT PROCESS OF SOFTWARE DEVELOPMENT PROJECTS FOR SUPPORTING STRATEGIC BUSINESS OBJECTIVES IN SOFTWARE DEVELOPING COMPANIES  

Directory of Open Access Journals (Sweden)

Full Text Available Software developing companies work in a competitive market and are often challenged to make business decisions with impact on competitiveness. Models accessing maturity for software development processes quality, such as CMMI and MPS-BR, comprise process measurements systems (PMS. However, these models are not necessarily suitable to support business decisions, neither to achieve strategic goals. The objective of this work is to analyze how the PMS of software development projects could support business strategies for software developing companies. Results taken from this work show that PMS results from maturity models for software processes can be suited to help evaluating operating capabilities and supporting strategic business decisions.

Sandra Lais Pedroso

2013-08-01

173

Project management for information system development  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Nowadays, with the development of the information and communication technology, information systems have been developing rapidly. More and more software companies choose to develop the information system to be their main business. They want to increase their business profits by developing the information system. However, the failure rate of developing information system has been high during these years. The purpose of the thesis is to discover how to use project management knowledge to improv...

Zhang, Yang

2011-01-01

174

Recent developments at MLLTRAP: Improving the system for mass measurements and in-trap observation of nuclear decays  

International Nuclear Information System (INIS)

Highlights: • A MPS system for m/q separation is developed. • A “detector trap” inside a Penning trap magnet is developed for the future MATS facility. • A novel type of recoil-distance experiment is envisaged. -- Abstract: The MLLTRAP double Penning-trap setup, installed at the Maier-Leibnitz Laboratory in Garching, presently serves as an environment for development work for mass spectrometry and decay-spectroscopy experiments at future radioactive ion beam (RIB) facilities. Here, an m/q separator is presently being set up as an element for beam transport of charge-bred ions, which are required for mass measurements of highly-charged ions. Moreover, a novel type of experimental setup, dedicated to in-trap decay spectroscopy, is under development to be implemented in the future MATS facility at FAIR. It combines the high-resolution mass-purification capabilities of a Penning trap with a customized “detector-trap” setup, consisting of an arrangement of position-sensitive Si-strip detectors that replaces the conventional ring electrode of the trap, providing both, ion storage and detection of decay products. In this way, decay-spectroscopy experiments of mass-selected nuclides, trapped as a carrier-free source, thus avoiding any background or scattering effects, will become feasible via direct in situ spectroscopy of stored ions

175

Targeting of the SUN protein Mps3 to the inner nuclear membrane by the histone variant H2A.Z.  

Science.gov (United States)

Understanding the relationship between chromatin and proteins at the nuclear periphery, such as the conserved SUN family of inner nuclear membrane (INM) proteins, is necessary to elucidate how three-dimensional nuclear architecture is established and maintained. We found that the budding yeast SUN protein Mps3 directly binds to the histone variant H2A.Z but not other histones. Biochemical and genetic data indicate that the interaction between Mps3 and H2A.Z requires the Mps3 N-terminal acidic domain and unique sequences in the H2A.Z N terminus and histone-fold domain. Analysis of binding-defective mutants showed that the Mps3-H2A.Z interaction is not essential for any previously described role for either protein in nuclear organization, and multiple lines of evidence suggest that Mps3-H2A.Z binding occurs independently of H2A.Z incorporation into chromatin. We demonstrate that H2A.Z is required to target a soluble Mps3 fragment to the nucleus and to localize full-length Mps3 in the INM, indicating that H2A.Z has a novel chromatin-independent function in INM targeting of SUN proteins. PMID:21518795

Gardner, Jennifer M; Smoyer, Christine J; Stensrud, Elizabeth S; Alexander, Richard; Gogol, Madelaine; Wiegraebe, Winfried; Jaspersen, Sue L

2011-05-01

176

ADASAGE, ADA Application Development System  

International Nuclear Information System (INIS)

.SRC and creates and edits schemes, forms, and report formats and compile the .SRC file into the .DFL file used by the application. The application will have unique requirements not satisfied by the selected utilities of ADASAGE. The code for these along with the code necessary to import and use the selected ADASAGE utilities constitutes the programmed application. The completed application system will contain the .DFL file produced by the THOR editor, the required ADASAGE utilities, and the programmed application. During the course of normal database development and use, restructuring and/or rebuilding of database files may be required if the schema for a record is modified (new fields are added, changed, or deleted and new keys selected, etc.), or if the index file for a relation becomes damaged or is destroyed. Program REBUILD performs this task. The rebuilding process is invoked by supplying both an old .DFL file name identifying the schema definition under which the current data was written and a current .DFL file name identifying the new schema definition to which the current database must be changed. REBUILD compares the old and current schema definitions for a relation, adjusts the database files accordingly, and re-tags the database files with the new version so that access with the new schema is allowed. The index file for the relation is then rebuilt, and any unused space within the database files removed. 3 - Restrictions on the complexity of the problem: Maxima for each ADASAGE database are: 4,294,967,000 records (tuples) per record size; 32,000 bytes record (tuple) size; 32,000 fixed-length field (attribute size); 4,294,967,000 variable-length field (attribute) size; 1,000 relations (flat files); 1,000 joined relations; 1,000 views; 500 fields (attributes) per relation; 500 keyed fields per relation; 6,550 forms (windows); 55 significant digits in a number. The user's operating system or hardware may have more stringent limits than these

177

Development of autonomous operation system  

International Nuclear Information System (INIS)

To enhance operation reliability of nuclear plants by removing human factors, study on an autonomous operation system has been carried out to substitute artificial intelligence (AI) for plant operators and, in addition, traditional controllers used in existing plants. For construction of the AI system, structurization of knowledge on the basis of the principles such as physical laws, function and structure of relevant objects and generalization of problem solving process are intended. A hierarchical distributed cooperative system configuration in employed because it is superior from the viewpoint of dynamical reorganization of system functions. This configuration is realized by an object-oriented multi-agent system. Construction of a prototype system was planned and the conceptual design was made for FBR plant in order to evaluate applicability of AI to the autonomous operation and to have a prospect for the realization of the system. The prototype system executes diagnosis, state evaluation, operation and control for the main plant subsystems. (author)

178

APPROACHING DEVELOPMENT IN LOGISTIC INFORMATION SYSTEMS  

Directory of Open Access Journals (Sweden)

Full Text Available The introduction of technology into modern defence necessitates integrated computerized information systems to render effective and efficient logistic support. Traditional information system development does not ensure attainment of use and time scale requirements in the continuously developing environment of logistics. This paper describes current approaches to the development of logistic information systems.

Louis F Buys

2012-01-01

179

Mutagenic potential scale developed for relative evaluation of biological system response to environments presenting different gamma exposure rates; Escala de potencial mutagenico (EPM) desenvolvida para avaliar, relativamente a resposta de sistemas biologicos a ambientes apresentando maiores ou menores taxas de exposicao gama  

Energy Technology Data Exchange (ETDEWEB)

The elaboration of a mutagenic potential scale (MPS) will be accomplished through the evaluation of the frequency of induced mutations in a plant biological system in different sites. The selection of these sites will be based on general public perception of risk to health. In this selection, it will include areas such ecological paradises and also neighborhoods of nuclear reactors and uranium mining and milling industry with potential radiological impact. The developed project foresees the contribution of other research groups that will also provide data from different sites. The referred scale will be built based on the response of the genetic system that gives color to the cells of Tradescantia (BNL 4430) stamen hair to mutagenic agents. Methodological improvements has been developed aiming the computerization of mutagenic events evaluation and statistical analysis of data that will significantly increase the efficiency of the system and obtention of results. Other biological systems of environmental quality are being added to the project, for future use. MPS should facilitate the general public and professionals of the nuclear area to understand risks, on a biological basis, of exposure from radiologically impacted environments. (author) 7 refs.

Nouailhetas, Yannick; Almeida, Carlos E. Bonacossa de; Mezrahi, Arnaldo; Shu, Jane; Xavier, Ana Maria [Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil). Superintendencia de Licenciamento e Controle. Coordenacao de Instalacoes Nucleares

1999-11-01

180

Needs and Possibility of Involving Nuclear Power Plant in the Macedonian Power System  

International Nuclear Information System (INIS)

The Macedonian Power System (MPS) used to be a part of the former Yugoslav Power System, and it was connected to the European system by 400 kV transmission lines. At the present time, the MPS works isolated from the UCPTE, only connected to the Yugoslav and Greek power systems. The connections with the Bulgarian and Albanian power systems are on a lower voltage level. The reliability and stability of the MPS needs to be improved. Macedonia is located in the central area of the Balkan, where the transmission systems from other Balkan countries are crossing. in the near future, the Macedonian Power System needs to be linked to the European system. To prepare for the energy demand at the beginning of the 21-st century, when the local coal reserves get exhausted, Macedonia needs to start with activities for substitution of the existing coal-fired thermal power plants with nuclear plants. This paper discusses the activities for global development solutions in the area of power generation. (author)

 
 
 
 
181

Magnetic properties and specific heat of MPS 3 (M=Mn, Fe, Zn)  

Science.gov (United States)

The magnetic properties and specific heat of MPS 3 (M=Mn, Fe and Zn) have been investigated. While ZnPS 3 is non-magnetic, MnPS 3 and FePS 3 are antiferromagnets with the Neel temperature TN of 78 and 118 K, respectively. Nevertheless, the specific heat of MnPS 3 and FePS 3 is smaller than that of ZnPS 3 below about 20 K. The temperature dependence of the magnetic specific heat CM of MnPS 3 shows a broad hump which is characteristic to the two dimensional magnetic materials and a small sharp peak at TN. On the other hand, that of FePS 3 shows a large sharp peak at TN. As for FePS 3, the temperature dependences of the magnetization M and CM are well reproduced by taking account of the magneto-elastic effect which introduces an additional term proportional to the square of the average value of the spin to the exchange coupling constant. As for MnPS 3, marked two dimensional characters apear in the temperature dependence of M and CM. The observed TN is much smaller than the paramagnetic Curie temperature of 240 K obtained from the temperature dependence of the magnetic susceptibility at high temperature.

Takano, Y.; Arai, N.; Arai, A.; Takahashi, Y.; Takase, K.; Sekizawa, K.

182

[Development of smart infusion system].  

Science.gov (United States)

The free care smart infusion system which has the function of liquid end alarm and automatic stopping has been designed. In addition, the system can send the alarm to the health care staff by Zigbee wireless network. Besides, the database of infusion information has been set up, it can be used for inquiry afterwards. PMID:24839846

Li, Junyang

2014-01-01

183

Infrared polarimetric camera system development  

Science.gov (United States)

The Defence Evaluation and Research Agency (DERA) has a requirement for an IRPC system to detect surface laid and buried anti-tank landmines in support of Phase 2 of the REmote Minefield Detection System Technology Demonstration Program. Nichols Research Corporation is currently under contact to DERA to design and fabricate the IRPC system for integration in the REMIDS TDP. The IRPC is a Stokes 4-vector IR camera system designed to operate form a static tower, a moving elevated surface platform or a moving airborne platform and will be used to demonstrate the usefulness of passive IR polarimetry for mine and minefield detection. DERA will use the IRPC system to investigate the feasibility of using polarimetric techniques to detect buried and surface laid mines from an airborne platform when operated in conjunction with an ultra wideband SAR.

Barnes, Howard B.; Jones, Michael W.; Bishop, Paul K.

1999-08-01

184

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress  

Science.gov (United States)

Aneuploidy is a hallmark of human solid cancers that arises from errors in mitosis and results in gain and loss of oncogenes and tumor suppressors. Aneuploidy poses a growth disadvantage for cells grown in vitro, suggesting that cancer cells adapt to this burden. To understand better the consequences of aneuploidy in a rapidly proliferating adult tissue, we engineered a mouse in which chromosome instability was selectively induced in T cells. A flanked by Lox mutation was introduced into the monopolar spindle 1 (Mps1) spindle-assembly checkpoint gene so that Cre-mediated recombination would create a truncated protein (Mps1DK) that retained the kinase domain but lacked the kinetochore-binding domain and thereby weakened the checkpoint. In a sensitized p53+/? background we observed that Mps1DK/DK mice suffered from rapid-onset acute lymphoblastic lymphoma. The tumors were highly aneuploid and exhibited a metabolic burden similar to that previously characterized in aneuploid yeast and cultured cells. The tumors nonetheless grew rapidly and were lethal within 3–4 mo after birth. PMID:25197064

Foijer, Floris; Xie, Stephanie Z.; Simon, Judith E.; Bakker, Petra L.; Conte, Nathalie; Davis, Stephanie H.; Kregel, Eva; Jonkers, Jos; Bradley, Allan; Sorger, Peter K.

2014-01-01

185

Developing a Comprehensive Reward System.  

Science.gov (United States)

Providing incentives for teachers of adults is an important means of attracting, retaining, and stimulating staff. Developing a variety of extrinsic and intrinsic rewards and incentives and instituting them effectively are important administrative functions. (SK)

Votruba, James C.

1979-01-01

186

States Develop Quality Data Systems  

Science.gov (United States)

Quality data can be a powerful tool for teachers, administrators and policymakers to use when trying to improve schools or individual programs. Data can show if a dropout prevention program is working; if students are entering postsecondary programs ready to learn; and how students are doing once they leave the P-20 educational system. This…

Kiker, Jason

2009-01-01

187

Optical strain measurement system development  

International Nuclear Information System (INIS)

A laser speckle, differential strain measurement system has been built and tested for future applications in hostile environments. One-dimensional electronic correlation of speckle pattern movement allows a quasi-real time measure of strain. The system has been used successfully to measure uniaxial strain reaching into plastic deformation of a test specimen, at temperatures ranging to 450 C. A resolution of 126 microstrain is given by the photodiode array sensor pitch and the specimen to sensor separation. The strain measurement error is estimated to be +/-18 microstrain +/-3 percent of the strain reading. The upper temperature limit of the gauge is determined by air density perturbations causing decorrelation of the reference and shifted speckle patterns, and may be improved by limiting convective flow in the immediate vicinity of the test specimen

188

Optical strain measurement system development  

Science.gov (United States)

A laser speckle, differential strain measurement system has been built and tested for future applications in hostile environments. One-dimensional electronic correlation of speckle pattern movement allows a quasi-real time measure of strain. The system has been used successfully to measure uniaxial strain reaching into plastic deformation of a test specimen, at temperatures ranging to 450 C. A resolution of 126 microstrain is given by the photodiode array sensor pitch and the specimen to sensor separation. The strain measurement error is estimated to be +/-18 microstrain +/-3 percent of the strain reading. The upper temperature limit of the gauge is determined by air density perturbations causing decorrelation of the reference and shifted speckle patterns, and may be improved by limiting convective flow in the immediate vicinity of the test specimen.

Lant, Christian T.; Qaqish, Walid

1988-01-01

189

Developing high performance manufacturing systems  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The work detailed in this dissertation relates to thedevelopment of high performance manufacturing systems. Theperformance factor aimed for is especially flexibility, butthere is an intention of making the results adaptable to focuson performance factors of the readers or users choice. Thefocus of the presented research is not only to provide meansfor accomplishing manufacturing that can handle changes butalso to accomplish flexibility in another area. The resultsshould be applicable in many ...

Karlsson, Anders

2002-01-01

190

Eurofix System and its Developments  

Science.gov (United States)

This paper, and the following six papers, were presented during the NAV 98 Conference held at Church House, Westminster, London on 9th and 10th December 1998. A full listing of the Conference, and how to obtain a copy of the proceedings, is shown on Page 300.The existing Loran-C and Chayka infrastructure can, with some minor changes, become a very powerful augmentation system for GNSS (GPS, GLONASS and the future Galileo). Delft University initially proposed the Eurofix concept in 1989. Although the necessary modification to the LF navigation systems are minimal, the GNSS user may get significant benefits from the Eurofix signals in terms of accuracy, integrity and availability. The reason is the high signal structure, signal propagation, and the operations dissimilarity of both systems. The broadcast correction and integrity data improves GNSS accuracy down to the metre level. In this way, the measured Loran-C and Chayka ranges are continuously updated. Thus, in the case of GNSS signal interruptions, highly calibrated Loran-C/Chayka may take over the navigation function. Tests carried out in Europe at the Loran-C station at Sylt (Germany) drew large international attention, leading to further tests in the USA by the US Coast Guard in 1998. Recently, a Dutch-Russian consortium implemented Eurofix on the Chayka transmitter at Bryansk (Russia) which is now successfully broadcasting DGPS as well as DGLONASS correction data. This paper highlights some on-air Eurofix DGPS performance experiments carried out in Europe and the USA. With all the European Loran-C and Chayka transmitters modified, Eurofix can be used all over the European continent. As multiple stations can normally be received simultaneously, the user may locally apply networked DGNSS, which may reduce spatial decorrelation effects significantly. Post-processed results of this Regional Area Augmentation System are presented.

Offermans, G. W. A.; Helwig, A. W. S.; van Willigen, D.

191

Development of geophysical data management system  

Energy Technology Data Exchange (ETDEWEB)

(1) Development of a complete geophysical database system under C/S environment for data management. (2) Development of database system for the general user, who has not special knowledge of database, under the Internet environment. (3) Operation of the Web service for the general user. (4) Development of the stand-alone database system for a small-scale research group such as college and engineering consultant firms. (author). 15 refs.

Lee, Tai-Sup; Lee, Sang-Kyu; Gu, Sung-Bon [Korea Institute of Geology Mining and Materials, Taejon (KR)] (and others)

1999-12-01

192

Developing TRUPACT system impact resistance  

International Nuclear Information System (INIS)

The Transportation Technology Center at Sandia National Laboratories has taken the lead in the development of the TRansUranic PACkage Transporter I (TRUPACT-I) for transporting contact-handled transuranic waste. TRUPACT-I is a Type B package designed for transport by truck and rail. One of the regulatory requirements of a Type B package is that it survive a drop onto a 15.2-cm-dia punch. This paper discusses the development of the puncture resistant panels used in TRUPACT-I. Concepts tested ranged from monolithic steel plates to laminated Kevlar fabric bonded to a steel backing plate. The TRUPACT-I wall design incorporated the laminated Kevlar and stainless steel puncture panel

193

Development of low-toxicity gelcasting systems  

Energy Technology Data Exchange (ETDEWEB)

A series of low-toxicity gelcasting systems has been developed. The reagents used in these systems have very low acute toxicity. The new systems perform at least as well as, and in some cases better than, the original acrylamide-based system. The development of these systems is described herein, including the search for new gel compositions, the study of suspensions made with the new gel precursor solutions, and pyrolysis of the dried gels and gelcast parts. Applications of the new gelcasting systems include complex silicon nitride parts, large-diameter rings, rapid prototyping by green machining, and metal-powder gel casting.

Janney, M.A.; Omatete, O.O.; Walls, C.A.; Nunn, S.D.; Ogle, R.J.; Westmoreland, G. [Oak Ridge National Lab., TN (United States). Metals and Ceramics Div.

1998-03-01

194

Autonomous Systems Developments and Trends  

CERN Document Server

The Workshops on Autonomous Systems emanated from a gathering with the doctoral students of just three chairs at Fernuniversität in Hagen, which we organise twice per year for a number of years now. Their purpose is to discuss on-going research and to create a community spirit. Furthermore, they serve as a means of structuring the students' research processes. The workshop has grown and matured in several respects. The doctoral students presenting their work do not come from a single university anymore, but from three. Besides them and their supervisors, also other scientists became interested in the event and contribute to its programme. Following the model of Advanced Study Institutes, they are available on the premises for relaxed, informal discussions outside the formal sessions. Finally, with the co-sponsorship of Gesellschaft für Informatik, the German Computer Society, and this surprisingly comprehensive volume of contributions published by Springer-Verlag the workshop turned into a visible scientifi...

Kyamaky, Kyandoghere; Kacprzyk, Janusz

2012-01-01

195

Real-Time Sensor Validation System Developed  

Science.gov (United States)

Real-time sensor validation improves process monitoring and control system dependability by ensuring data integrity through automated detection of sensor data failures. The NASA Lewis Research Center, Expert Microsystems, and Intelligent Software Associates have developed an innovative sensor validation system that can automatically detect automated sensor failures in real-time for all types of mission-critical systems. This system consists of a sensor validation network development system and a real-time kernel. The network development system provides tools that enable systems engineers to automatically generate software that can be embedded within an application. The sensor validation methodology captured by these tools can be scaled to validate any number of sensors, and permits users to specify system sensitivity. The resulting software reliably detects all types of sensor data failures.

Zakrajsek, June F.

1998-01-01

196

The development of warehause control system  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Warehouse Control System is information system for automated warehouse process management. It fills the gap between WMS systems and programmable logic controllers of automated warehouse devices. The presented work offers possible design and implementation of such system with the help of some of the latest Microsoft technologies for software development. Special attention was devoted to WCF framework and database design, which is the foundation of any information system. WCF framework ke...

Svete, Tine

2010-01-01

197

Recent Developments on Chaos in Mechanical Systems  

Directory of Open Access Journals (Sweden)

Full Text Available Recent advancements in complexity of mechanical systems have led to the application of chaos theory. In this paper, some recent developments on chaos in mechanical systems are explored. The aim is to bring together researchers from various interests of mechanical systems, exposing them to chaos theory. This exposure gives researchers from the discipline of mechanical systems to find opportunity of cross disciplinary research, which may ultimately lead to novel solutions and understanding of mechanical systems.

Mohammad Sajid

2013-10-01

198

Safeguards -Safeguards system development support-  

International Nuclear Information System (INIS)

This project mainly focused to technically support national safeguards inspection which is scheduled in the beginning of 1997. It includes non-destructive assay of nuclear fuels, analysis on inspection and environmental samples, remote monitoring of nuclear activities and its analysis, survey on remote sensing of satellite for safeguards application. Non-destructive assay of nuclear fuels dealt with development on verification of spent fuels with emphasis to fabrication of inspection tools with surveillance and gamma measurement on CANDU spent fuels. For sample analysis, study was carried out on process inspection sample analysis method. In addition to this, ultra low background laboratory was set up to execute environmental and swipe samples and sample treatment techniques including water, soil, plant, et al. were researched. Tritiums which were sampled around power plants were analysed. With cooperation of Satellite Technology Research Center of KAIST, use of civilian satellite imagery was surveyed. To train facility operators for safeguards, various technology on non-destructive assay was lectured to personnel of Korea Electric Power Corporation. And to enhance out capabilities, non-destructive assay training was done at Los Alamos National Lab. of U.S. through the agreement of MOST and DOE agreement, and information on DA technology was exchanged at Nuclear Material Control Center of Japan. (author). 22 tabs., 52 figs., 53

199

Development of Residential SOFC Cogeneration System  

International Nuclear Information System (INIS)

Since 2001 Kyocera has been developing 1kW class Solid Oxide Fuel Cell (SOFC) for power generation system. We have developed a cell, stack, module and system. Since 2004, Kyocera and Osaka Gas Co., Ltd. have been developed SOFC residential co-generation system. From 2007, we took part in the 'Demonstrative Research on Solid Oxide Fuel Cells' Project conducted by New Energy Foundation (NEF). Total 57 units of 0.7kW class SOFC cogeneration systems had been installed at residential houses. In spite of residential small power demand, the actual electric efficiency was about 40%(netAC,LHV), and high CO2 reduction performance was achieved by these systems. Hereafter, new joint development, Osaka Gas, Toyota Motors, Kyocera and Aisin Seiki, aims early commercialization of residential SOFC CHP system.

200

Development of Residential SOFC Cogeneration System  

Science.gov (United States)

Since 2001 Kyocera has been developing 1kW class Solid Oxide Fuel Cell (SOFC) for power generation system. We have developed a cell, stack, module and system. Since 2004, Kyocera and Osaka Gas Co., Ltd. have been developed SOFC residential co-generation system. From 2007, we took part in the "Demonstrative Research on Solid Oxide Fuel Cells" Project conducted by New Energy Foundation (NEF). Total 57 units of 0.7kW class SOFC cogeneration systems had been installed at residential houses. In spite of residential small power demand, the actual electric efficiency was about 40%(netAC,LHV), and high CO2 reduction performance was achieved by these systems. Hereafter, new joint development, Osaka Gas, Toyota Motors, Kyocera and Aisin Seiki, aims early commercialization of residential SOFC CHP system.

Ono, Takashi; Miyachi, Itaru; Suzuki, Minoru; Higaki, Katsuki

2011-06-01

 
 
 
 
201

Development of Residential SOFC Cogeneration System  

Energy Technology Data Exchange (ETDEWEB)

Since 2001 Kyocera has been developing 1kW class Solid Oxide Fuel Cell (SOFC) for power generation system. We have developed a cell, stack, module and system. Since 2004, Kyocera and Osaka Gas Co., Ltd. have been developed SOFC residential co-generation system. From 2007, we took part in the 'Demonstrative Research on Solid Oxide Fuel Cells' Project conducted by New Energy Foundation (NEF). Total 57 units of 0.7kW class SOFC cogeneration systems had been installed at residential houses. In spite of residential small power demand, the actual electric efficiency was about 40%(netAC,LHV), and high CO2 reduction performance was achieved by these systems. Hereafter, new joint development, Osaka Gas, Toyota Motors, Kyocera and Aisin Seiki, aims early commercialization of residential SOFC CHP system.

Ono, Takashi; Miyachi, Itaru [KYOCERA CORPORATION, R and D Center, Kagoshima, 1-4, Yamashita-cho, Kokubu, Kirishima-shi, Kagoshima (Japan); Suzuki, Minoru; Higaki, Katsuki, E-mail: takashi.ono.cy@kyocera.jp [OSAKA GAS Co., Ltd., Fuel Cell Development Department, 6-19-9, Torishima, Konohana-ku, Osaka (Japan)

2011-06-15

202

Development of sorting system control using LABVIEW  

International Nuclear Information System (INIS)

The development of the Personnel Dosimeter Sorting System, proposed by the Secondary Standard Dosimetry Laboratory (SSDL) is to enhance the system or work flow in preparing the personnel dosimeter. The main objective of the system is to reduce stamping error, time and cost. The Personnel Dosimeter Sorting System is a semi-automatic system with an interfacing method using the Advantec 32 bit PCI interface card of 64 digital input and output. The system is integrated with the Labview version 7.1 programming language to control the sorting system and operation. (Author)

203

Developing Sustainable Life Support System Concepts  

Science.gov (United States)

Sustainable spacecraft life support concepts may allow the development of more reliable technologies for long duration space missions. Currently, life support technologies at different levels of development are not well evaluated against each other, and evaluation methods do not account for long term reliability and sustainability of the hardware. This paper presents point-of-departure sustainability evaluation criteria for life support systems, that may allow more robust technology development, testing and comparison. An example sustainable water recovery system concept is presented.

Thomas, Evan A.

2010-01-01

204

Advanced Mating System Development for Space Applications  

Science.gov (United States)

This slide presentation reviews the development of space flight sealing and the work required for the further development of a dynamic interface seal for the use on space mating systems to support a fully androgynous mating interface. This effort has resulted in the advocacy of developing a standard multipurpose interface for use with all modern modular space architecture. This fully androgynous design means a seal-on-seal (SOS) system.

Lewis, James L.

2004-01-01

205

NASA develops new digital flight control system  

Science.gov (United States)

This news release reports on the development and testing of a new integrated flight and propulsion automated control system that aerospace engineers at NASA's Ames Research Center have been working on. The system is being tested in the V/STOL (Vertical/Short Takeoff and Landing) Systems Research Aircraft (VSRA).

Mewhinney, Michael

1994-01-01

206

Toward the Development of Expert Assessment Systems.  

Science.gov (United States)

The potential application of "expert systems" to the diagnosis and assessment of special-needs children is examined and existing prototype systems are reviewed. The future of this artificial intelligence technology is discussed in relation to emerging development tools designed for the creation of expert systems by the lay public. (Author)

Hasselbring, Ted S.

1986-01-01

207

Risks in Information Systems Development Projects  

Directory of Open Access Journals (Sweden)

Full Text Available Risk is a part of all aspects of everyday life. Development of an informational system is a complex process, which makes it submissive to a great number of risks. Many projects do not achieve previously set goals, therefore risk management is not to be ignored in the development of informational systems. In this paper, the efficacy of IS development, as well as a number of risks influencing the project development, are considered. Also, attention is paid to the risk management methodology, simultaneously setting a framework for risk management in IS development.

Lazar Rakovi?

2009-06-01

208

System model development for nuclear thermal propulsion  

International Nuclear Information System (INIS)

A critical enabling technology in the evolutionary development of nuclear thermal propulsion (NTP) is the ability to predict the system performance under a variety of operating conditions. Since October 1991, US (DOE), (DOD) and NASA have initiated critical technology development efforts for NTP systems to be used on Space Exploration Initiative (SEI) missions to the Moon and Mars. This paper presents the strategy and progress of an interagency NASA/DOE/DOD team for NTP system modeling. It is the intent of the interagency team to develop several levels of computer programs to simulate various NTP systems. An interagency team was formed for this task to use the best capabilities available and to assure appropriate peer review. The vision and strategy of the interagency team for developing NTP system models will be discussed in this paper. A review of the progress on the Level 1 interagency model is also presented

209

System model development for nuclear thermal propulsion  

Energy Technology Data Exchange (ETDEWEB)

A critical enabling technology in the evolutionary development of nuclear thermal propulsion (NTP) is the ability to predict the system performance under a variety of operating conditions. Since October 1991, US (DOE), (DOD) and NASA have initiated critical technology development efforts for NTP systems to be used on Space Exploration Initiative (SEI) missions to the Moon and Mars. This paper presents the strategy and progress of an interagency NASA/DOE/DOD team for NTP system modeling. It is the intent of the interagency team to develop several levels of computer programs to simulate various NTP systems. An interagency team was formed for this task to use the best capabilities available and to assure appropriate peer review. The vision and strategy of the interagency team for developing NTP system models will be discussed in this paper. A review of the progress on the Level 1 interagency model is also presented.

Walton, J.T. [National Aeronautics and Space Administration, Cleveland, OH (United States). Lewis Research Center; Hannan, N.A. [Argonne National Lab., IL (United States); Perkins, K.R. [Brookhaven National Lab., Upton, NY (United States); Buksa, J.J. [Los Alamos National Lab., NM (United States); Worley, B.A. [Oak Ridge National Lab., TN (United States); Dobranich, D. [Sandia National Labs., Albuquerque, NM (United States)

1992-10-01

210

Space Launch Flight Termination System initial development  

Science.gov (United States)

This paper describes the studies, capabilities and challenges in initial development of a new digital encrypted termination system for space launch vehicles. This system is called the Space Launch Flight Termination System (SLFTS). Development of SLFTS is required to address an obsolescence issue and to improve the security of flight termination systems presently in use on the nation's space launch vehicles. SLFTS development was implemented in a four phase approach with the goal of producing a high secure, cost effective flight termination system for United Launch Alliance (ULA) and the United States Air Force (USAF) Evolved Expendable Launch Vehicle (EELV). These detailed study phases developed the requirements, design and implementation approach for a new high secure flight termination system. Studies led to a cost effective approach to replace the High Alphabet Command Receiver Decoders (HA-CRD) presently used on the EELV (Delta-IV & Atlas-V), with a common SLFTS unit. SLFTS is the next generation flight termination system for space launch vehicles, providing an assured high secure command destruct system for launch vehicles in flight. The unique capabilities and challenges to develop this technology for space launch use will be addressed in this paper in detail. This paper summarizes the current development status, design and capabilities of SLFTS for EELV.

Ratkevich, B.; Brierley, S.; Lupia, D.; Leiker, T.

211

Development of linked vacuum interlock protection systems  

International Nuclear Information System (INIS)

Three linked vacuum interlock protection systems were developed for three U7 stations shared one beam line of National Synchrotron Radiation Laboratory. The system control principle, logical points and method were described. Optical fibre was used for communications between beam lines. By implementing the protection system, reliability and anti-jamming of the system were enhanced with fast response time. The response time of FCV valve can be reduced to 8 ms. (authors)

212

Psychology of developing and designing expert systems  

Energy Technology Data Exchange (ETDEWEB)

This paper discusses psychological problems relevant to developing and designing expert systems. With respect to the former, the psychological literature suggests that several cognitive biases may affect the elicitation of a valid knowledge base from the expert. The literature also suggests that common expert system inference engines may be quite inconsistent with reasoning heuristics employed by experts. With respect to expert system user interfaces, care should be taken when eliciting uncertainty estimates from users, presenting system conclusions, and ordering questions.

Tonn, B.; MacGregor, D.

1986-01-01

213

A Software Development Platform for Mechatronic Systems  

DEFF Research Database (Denmark)

Software has become increasingly determinative for development of mechatronic systems, which underscores the importance of demands for shortened time-to-market, increased productivity, higher quality, and improved dependability. As the complexity of systems is dramatically increasing, these demands present a challenge to the practitioners who adopt conventional software development approach. An effective approach towards industrial production of software for mechatronic systems is needed. This approach requires a disciplined engineering process that encompasses model-driven engineering and component-based software engineering, whereby we enable incremental software development using component models to address the essential design issues of real-time embedded systems. To this end, this dissertation presents a software development platform that provides an incremental model-driven development process based on a component-based modeling framework and a number of component-based analysis methods. The framework offers modeling languages for specifying the system, functional components, runtime environment, and platform. Furthermore, the defined compositional and relational rules of these component models enable rigorous construction of systems. The incremental development process separates the development activities into prefabrication of reusable components, conguration and generation of applications using validated components, and elimination of design errors using model-based analysis and verfication methods. Especially, the latter methods employ appropriate techniques and tools for dierent aspects of design issues. Finally, the tool-chain supporting these technology is evaluated comparatively to validate the proposed methods and identify the advantages and disadvantages of the technologies developed in this work.

Guan, Wei

2012-01-01

214

3-D Simulation of Plunging Jet Penetration into a Denser Liquid Pool by the RD-MPS Method  

Energy Technology Data Exchange (ETDEWEB)

We used the rigid body dynamics coupled moving particle semi-implicit (RD-MPS) method to simulate a plunging liquid jet penetrating into a denser liquid pool in two and three dimensions. The simulating phenomenon is related to fuel-coolant interactions (FCI) during severe accidents in nuclear power plants when coolant water is forcedly injected into a melt pool. The simulation results suggested that the coupled model be useful in simulating dynamic interactions of multi-phase incompressible fluids as well as that the 3-D simulation for the plunging jet in a confined geometry predicted better agreement with experimental results than the 2-D simulation did

Park, Sha In [KEPCO Nuclear Fuel Co., Daejeon (Korea, Republic of); Park, Hyun Sun [Pohang University of Science and Technology, Pohang (Korea, Republic of); Joo, Hyeong Min; Jeun, Gyoo Dong [Hanyang University, Seoul (Korea, Republic of)

2012-05-15

215

Development of an autonomous power system testbed  

International Nuclear Information System (INIS)

A power system testbed has been assembled to advance the development of large autonomous electrical power systems required for the space station, spacecraft, and aircraft. The power system for this effort was designed to simulate single- or dual-bus autonomous power systems, or autonomous systems that reconfigure from a single bus to a dual bus following a severe fault. The approach taken was to provide a flexible power system design with two computer systems for control and management. One computer operates as the control system and performs basic control functions, data and command processing, charge control, and provides status to the second computer. The second computer contains expert system software for mission planning, load management, fault identification and recovery, and sends load and configuration commands to the control system

216

MSFC Lunar Environments Test System (LETS) System Development  

Science.gov (United States)

A review of the NASA MSFC Lunar Environment Test System (LETS) System Development is presented. The contents include: 1) MSFC LETS Chamber Status; 2) LETS Simulant Containment Box Development; 3) Tests Conducted in LETS To date: Simulant Dust Migration; 4) Summary; and 5) Forward Work.

Craven, Paul; Vaughn, Jason; Schneider, Todd; Norwood, Joey; Abbas, Mian; Alexander, Reginald

2009-01-01

217

Development of a Sound Quality Evaluation System  

DEFF Research Database (Denmark)

This paper describes the development of the first version of the Sound Quality Evaluation System. The purpose of the system is to predict the subjective sound quality of home theater systems from objective measurements. 16 home theater systems were measured in an anechoic room. Several metrics expected to correlate w ith the subjective quality were proposed and tested. A model for the sound quality was created by mapping the subjective evaluations of the Home Theater System s with the metrics calculated for each system. Correlation between subjective listening test and the prediction is presente

Agerkvist, Finn T.

2004-01-01

218

DEVELOPMENT OF ALUMINUM THERMAL BREAK SYSTEM  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The main purpose of the study was the development of a new system of aluminum profiles with thermal brakes R102 TERMO. The system must be based on the previous modification R72 TERMO. The system must be developed due to an early tightening of European regulations on thermal efficiency of buildings and structures which will take effect in 2012. Another purpose was to evaluate the possibility of production and sales of the new system in the Russian market. The theoretical part of the study...

Kosarev, Sergey

2011-01-01

219

Embedded systems development using Modula-2  

Science.gov (United States)

This lecture gives an overview of the kind and size of software systems which has been realized by Brown Boveri & Cie using the programming language Modula-2. It presents the fundamental concepts of Modula-2 and goes into detail with the facilities that are particularly useful for systems programming. Based on examples it is shown how the low-level constructs of Modula-2 can be used to create higher-level tools for synchronization, communication and direct hardware access — all desirable features for embedded systems development. The lecture also presents the various problems encountered during systems development.

Højlund Nielsen, Jan

1988-07-01

220

MODERN FACTORS OF UKRAINIAN EDUCATION SYSTEM DEVELOPMENT ??????? ??????? ???????? ??????? ?????? ???????  

Directory of Open Access Journals (Sweden)

Full Text Available Influence of integration, democratization and informatization society processes on the development and forming of education systems aims in European countries as well as in Ukraine is analyzed in the paper. It is considered the development of Ukrainian education system in direction of European integration, Bologna process, integration to the European education systems. Such modern phenomena as unified educational space, global educational space and open educational environment of education systems as well as the key role of information and communication technologies playing a great role in these processes have been determined and analyzed.? ?????? ?????????????? ????? ???????? ??????????, ?????????????? ?? ?????????????? ??????????? ?? ???????? ?? ?????????? ????? ?????? ?????? ?? ? ???????????? ???????,. ??? ? ? ???????. ?????????? ???????? ??????? ?????? ??????? ? ???????? ???????????? ??????????, ??????????? ???????, ?????????? ?? ???????????? ?????? ??????. ????????? ?? ?????????????? ???? ??????? ????? ?? ?????? ???????? ???????, ?????????? ???????? ??????? ?? ???????? ????????? ?????????? ?????? ??????, ? ????? ??????? ???? ????????????-?????????????? ??????????, ??? ???? ?????????? ? ??? ????????.

?.?. ?????

2010-08-01

 
 
 
 
221

Lentiviral-Mediated Gene Therapy Results in Sustained Expression of ?-Glucuronidase for up to 12 Months in the Gus(mps/mps) and up to 18 Months in the Gus(tm(L175F)Sly) Mouse Models of Mucopolysaccharidosis Type VII.  

Science.gov (United States)

Abstract A number of mucopolysaccharidosis type VII (MPS VII) mouse models with different levels of residual enzyme activity have been created replicating the range of clinical phenotypes observed in human MPS VII patients. In this study, a lentivirus encoding murine ?-glucuronidase was administered intravenously at birth to both the severe (Gus(mps/mps) strain) and attenuated (Gus(tm(L175F)Sly) strain) mouse models of MPS VII. Circulating enzyme levels were normalized in the Gus(mps/mps) mice and were 3.5-fold higher than normal in the Gus(tm(L175F)Sly) mouse 12 and 18 months after administration. Tissue ?-glucuronidase activity increased over untreated levels in all tissues evaluated in both strains at 12 months, and the elevated level was maintained in Gus(tm(L175F)Sly) tissues at 18 months. These elevated enzyme levels reduced glycosaminoglycan storage in the liver, spleen, kidney, and heart in both models. Bone mineral volume decreased toward normal in both models after 12 months of therapy and after 18 months in the Gus(tm(L175F)Sly) mouse. Open-field exploration was improved in 18-month-old treated Gus(tm(L175F)Sly) mice, while spatial learning improved in both 12- and 18-month-old treated Gus(tm(L175F)Sly) mice. Overall, neonatal administration of lentiviral gene therapy resulted in sustained enzyme expression for up to 18 months in murine models of MPS VII. Significant improvements in biochemistry and enzymology as well as functional improvement of bone and behavior deficits in the Gus(tm(L175F)Sly) model were observed. Therapy significantly increased the lifespan of Gus(mps/mps) mice, with 12 months being the longest reported lentiviral treatment for this strain. It is important to assess the long-term outcome on enzyme levels and effect on pathology for lentiviral gene therapy to be a potential therapy for MPS patients. PMID:25003807

Derrick-Roberts, Ainslie L K; Pyragius, Carmen E; Kaidonis, Xenia M; Jackson, Matilda R; Anson, Donald S; Byers, Sharon

2014-09-01

222

Development of the stock exchange information system  

Directory of Open Access Journals (Sweden)

Full Text Available The stock exchange represents the key institution for the development of capital market of any country. Thus the information system of every stock exchange must satisfy very strict international standards. The development of these systems is particularly difficult in countries in transition, due to intense economic and legal changes, lack of technical and financial resources, lack of experience and knowledge in the area of the capital market business, etc. Therefore the special software project management methodology for their realization must be clearly defined. In the development process of the Belgrade Stock Exchange (BSE information system a new software project management methodology for its realization has been defined, the application of which is illustrated through a series of different development stages of the Belgrade Stock Exchange information system. In order to make all the problems more comprehensive, only the continuous trading method is described, being the most frequently used trading method in the world.

Miladinovi? Radojko

2006-01-01

223

Development of Architectures for Internet Telerobotics Systems  

CERN Document Server

This paper presents our experience in developing and implementing Internet telerobotics system. Internet telerobotics system refers to a robot system controlled and monitored remotely through the Internet. A robot manipulator with five degrees of freedom, called Mentor, is employed. Client-server architecture is chosen as a platform for our Internet telerobotics system. Three generations of telerobotics systems have evolved in this research. The first generation was based on CGI and two tiered architecture, where a client presents a Graphical User Interface to the user, and utilizes the user's data entry and actions to perform requests to robot server running on a different machine. The second generation was developed using Java. We also employ Java 3D for creating and manipulating 3D geometry of manipulator links and for constructing the structures used in rendering that geometry, resulting in 3D robot movement simulation presented to the users(clients) through their web browser. Recent development in our In...

Bambang, Riyanto

2008-01-01

224

Usability Factors in Information Systems Development  

Directory of Open Access Journals (Sweden)

Full Text Available Computers have become a commonplace technology for today’s man. Computer users demand more reliable and durable interfaces from information processing applications developers. Information systems (ISs research and development, over the years, has been steady so well that the arena has now grown into various subfields such as Cognitive Information Systems (CISs, Web Information Systems(WISs, Geographical Information Systems(GISs, Enterprise Information Systems (EISs, and so forth. Of late, ergonomics specialization too has begun to percolate into the field making it more cross-fertilizing with concerns for successful deployment, a win-win model of development and look-and-feel factor in terms of durable usage and usability. The paper presents a novel taxonomy of computer ergonomics.

K. Chandra Sekharaiah

2014-07-01

225

Developing Digital Control System Centrifugal Pumping Unit  

Directory of Open Access Journals (Sweden)

Full Text Available Currently, the leading Russian oil companies engaged in the development of automatic control systems (ACS oil equipment, to improve its efficiency. As an example of an object needed to optimize its work, a centrifugal pumping unit (CPU can be specified. Frequency actuators provide an opportunity to run CPU in any algorithm, and many industrial controllers, are part of the automatic control system technological process (ACSTP, allow optimizing the operation of the centrifugal pumping unit and help determine the requirements for the development of digital automatic control system for CPU. The development of digital automatic control systems for such a complex nonlinear control object like CPU has several features that should be considered when designing control systems for that object.

Safarini Osama

2011-08-01

226

Motor Development International: Compressed Air Technology Systems  

Science.gov (United States)

How does a car that boasts "zero pollution" and even "cleans the air it uses" work? This website provides information on the air compression cars developed by Motor Development International. Aside from the general overview of the mechanics of air compression, the FAQ section provides additional information on the air tanks, filter system, body frame, electric system and MDI's business model. A key target for this website seems to be potential buyers and investors.

227

Hydrogen storage and delivery system development: Fabrication  

Energy Technology Data Exchange (ETDEWEB)

Hydrogen storage and delivery is an important element in effective hydrogen utilization for energy applications and is an important part of the FY1994-1998 Hydrogen Program Implementation Plan. This project is part of the Field Work Proposal entitled Hydrogen Utilization in Internal Combustion Engines (ICE). The goal of the Hydrogen Storage and Delivery System Development Project is to expand the state-of-the-art of hydrogen storage and delivery system design and development. At the foundation of this activity is the development of both analytical and experimental evaluation platforms. These tools provide the basis for an integrated approach for coupling hydrogen storage and delivery technology to the operating characteristics of potential hydrogen energy use applications. Analytical models have been developed for internal combustion engine (ICE) hybrid and fuel cell driven vehicles. The dependence of hydride storage system weight and energy use efficiency on engine brake efficiency and exhaust temperature for ICE hybrid vehicle applications is examined. Results show that while storage system weight decreases with increasing engine brake efficiency energy use efficiency remains relatively unchanged. The development, capability, and use of a newly developed fuel cell vehicle hydride storage system model will also be discussed. As an example of model use power distribution and control for a simulated driving cycle is presented. An experimental test facility, the Hydride Bed Testing Laboratory (HBTL) has been designed and fabricated. The development of this facility and its use in storage system development will be reviewed. These two capabilities (analytical and experimental) form the basis of an integrated approach to storage system design and development. The initial focus of these activities has been on hydride utilization for vehicular applications.

Handrock, J.L.; Malinowski, M.E.; Wally, K. [Sandia National Lab., Livermore, CA (United States)

1996-10-01

228

Modelling energy systems for developing countries  

International Nuclear Information System (INIS)

Developing countries' energy use is rapidly increasing, which affects global climate change and global and regional energy settings. Energy models are helpful for exploring the future of developing and industrialised countries. However, energy systems of developing countries differ from those of industrialised countries, which has consequences for energy modelling. New requirements need to be met by present-day energy models to adequately explore the future of developing countries' energy systems. This paper aims to assess if the main characteristics of developing countries are adequately incorporated in present-day energy models. We first discuss these main characteristics, focusing particularly on developing Asia, and then present a model comparison of 12 selected energy models to test their suitability for developing countries. We conclude that many models are biased towards industrialised countries, neglecting main characteristics of developing countries, e.g. the informal economy, supply shortages, poor performance of the power sector, structural economic change, electrification, traditional bio-fuels, urban-rural divide. To more adequately address the energy systems of developing countries, energy models have to be adjusted and new models have to be built. We therefore indicate how to improve energy models for increasing their suitability for developing countries and give advice on modelling techniques and data requirements

229

Epigenetic Systems View of Human Development.  

Science.gov (United States)

Discusses the history of the hierarchical epigenetic systems view as applied to human development and offers examples of its implementation. Notes the agreement by many authors that the multilevel systems view is the right model for developmental psychology in both human and animal studies. (BC)

Gottlieb, Gilbert

1991-01-01

230

Work Values System Development during Adolescence  

Science.gov (United States)

Work values stability, change, and development can be appreciably reduced to a living system model [Ford, D. H. (1994). "Humans as self-constructing living systems: A developmental perspective on behavior and personality" (2nd ed.). Hillsdale, NJ: Lawrence Erlbaum Associates]. This theoretical model includes discrepancy-reducing and…

Porfeli, Erik J.

2007-01-01

231

Evaluation Systems, Ethics, and Development Evaluation  

Science.gov (United States)

After some 65 years of international development assistance, it is still difficult to show the effectiveness of aid in ways that are fully convincing. In part, this reflects inadequacies in the evaluation systems of the bilateral, multilateral, and global organizations that provide official development aid. Underlying these weaknesses often are a…

Thomas, Vinod

2010-01-01

232

INDUSTRIAL RESEARCH AND DEVELOPMENT INFORMATION SYSTEM (IRIS)  

Science.gov (United States)

The National Science Foundation's (NSF) Industrial Research and Development Information System (IRIS) links an online interface to a historical database with more than 2,500 statistical tables containing all industrial research and development (R&D) data published by NSF since 19...

233

Technical development for Australia's MOBILESAT system  

Science.gov (United States)

With the planned introduction in Australia of the mobile satellite service in mid-1992, MOBILESAT will be the first domestic mobile satellite system with full voice and data capability to be in operation worldwide. This paper describes the technical features which have been adopted by MOBILESAT in providing a unique system optimized for land mobile operation and the technical activities which have been carried out by AUSSAT in the past three years in supporting the development of the system.

Dinh, Kim; Hart, Nick; Harrison, Steve

1990-01-01

234

DEVELOPMENT OF INTELLIGENT SECURITY AND AUTOMATION SYSTEM  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Intelligent security and Automation system is a device that intends to solve the security issues and also provides automation facilities. the two aspects of security and automation are distinguished by a selector switch. the goal is to develop an intelligent security & automation system that gives the user complete security and automation services. this system can work in two modes as indoor mode and outdoor mode. in outdoor mode it provides complete security of the user place and in indoor m...

Diwakar Saxena, Puneet Bisen

2012-01-01

235

Common N-acetylgalactosamine-6-sulfate sulfatase (GALNS) exon mutations in Brazilian patients with mucopolysaccharidosis IVA (MPS IVA)  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english Morquio A Syndrome (mucopolysaccharidosis IVA - MPS IVA, OMIM# 253000) is an autosomal recessive inborn error of metabolism caused by the deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS). We investigated five unrelated Brazilian MPS IVA families for mutations in exons 4, 5, 9 and 10 o [...] f the GALNS gene. Six out of the 10 mutant alleles were identified. Taken together with a previous study, which included six unrelated families, common mutations among Brazilian patients were p.N164T, p.G116S and p.G301C. Among one hundred control subjects three novel silent mutations were found (p.A107A; GCC -> GCT, p.Y108Y; TAC -> TAT, p.P357P; CCG -> CCA). Screening starting with exons 4, 5, 9, 10 and 11 may be a good strategy for genotyping of Brazilian patients since these exons include 73% of all mutations identified in the current and previous studies.

Tatiana, Dieter; Ursula da Silveira, Matte; Ida Vanessa, Schwartz; Shunji, Tomatsu; Roberto, Giugliani.

236

Clinical Analysis about Diagnosis and Treatment of 86 Hand Paresthesia Cases Using MPS Theory and Pharmacopuncture Therapy  

Directory of Open Access Journals (Sweden)

Full Text Available Objectives : Hand paresthesia is common syndrome and the cause is more unknown than known reason. The Purpose of this study were investigated the effects of Myofacial Pain Syndrome theory to make diagnosis and treatment by Pharmacopuncture for the patients of hand paresthesia. Method : This study was carried out to established the clinical criteria of hand parethesia. The patients who had past history of diabeics, neuropathy induced by alcohol or drug were excluded, and 86 patients who had hand paresthesia related with unknown-reason was selected by the interview process. And the effects of Pharmacopuncture theory were analyzed using VAS score before and after treatment. Results and conclusions : 56.9% of unknown-reason patients are positive at diagnosis by MPS theory. While positive group decrease from 62.81±14.27 to 25.28±15.97, negative group decrease from 55.88±10.92 to 48.28±14.01 by VAS scores. Positive group was accordingly more effective than negative group. So diagnosis and treatment for hand numbness patients by MPS theory was useful in clinical.

Sung-Won Oh

2007-12-01

237

Investigation of current transport parameters of Ti/4H-SiC MPS diode with inhomogeneous barrier  

International Nuclear Information System (INIS)

The current transport parameters of 4H-SiC merged PiN Schottky (MPS) diode are investigated in a temperature range of 300–520 K. Evaluation of the experimental current–voltage (I—V) data reveals the decrease in Schottky barrier height ?b but an increase in ideality factor n, with temperature decreasing, which suggests the presence of an inhomogeneous Schottky barrier. The current transport behaviours are analysed in detail using the Tung's model and the effective area of the low barrier patches is extracted. It is found that small low barrier patches, making only 4.3% of the total contact, may significantly influence the device electrical characteristics due to the fact that a barrier height of 0.968 eV is much lower than the average barrier height 1.39 eV. This shows that ion implantation in the Schottky contact region of MPS structure may result in a poor Ti/4H-SiC interface quality. In addition, the temperature dependence of the specific on-resistance (Ron—sp), T2.14, is determined between 300 K and 520 K, which is similar to that predicted by a reduction in electron mobility. (condensed matter: electronic structure, electrical, magnetic, and optical properties)

238

The HS6000/20 development system  

International Nuclear Information System (INIS)

In the actual control system of MEA, NIKHEF-K three color displays are in use for graphical representation of the accelerator status information. At the moment the quality of the color displays is bad. The HS6000 development system of the English company Syntel seems to offer a possible solution to replace these displays. In the development system software is developed which finally may run on a target module. The target module, consisting of a processor card with memory and RS232 port and a graphical card, takes care for the control of a color display. The institute has disposed of an experimental set up during two weeks in order to investigate the possibilities and limitations of the development system. The HS6000 development system runs under the OS-9 multi-user and multi-tasking operating system. The operating system takes care for a part of the necessary software to render a computer valuable. The OS-9 operating system disposes of about 60 utility commands. A feature of OS-9 is the application of modular software technique which are based upon memory modules. The interface between the user and the internal functions of the operating system is formed from the shell, the OS-9 command-interpreter code. The software, which has to run on the target module, is written with the help of the Mmacs screen editor, the draw program and the medit editor. The draw program and the medit editor form part of the EGOS ( Enhanced Graphical Output Software) packet. The EGOS packet is a multi-tasking graphical interface for the OS-9 operating system. (author). 1 fig

239

Development of the simulation monitoring system  

International Nuclear Information System (INIS)

Large-scale simulation technique is studied at the Center for Promotion of Computational Science and Engineering for the computational science research in nuclear fields. Visualization and animation processing techniques are developed for efficient understanding of simulation results. The development of the simulation monitoring system, which is used for real-time visualization of ongoing simulations or for successive visualization of calculated results, is described in this report. The standard visualization tool AVS5 or AVS/EXPRESS is used for the simulation monitoring system, and thus, this system can be utilized in various computer environments. (author)

240

70 FR 71367 - Data-Link Recorder Systems  

Science.gov (United States)

...Standard Order (TSO) C-177, Data-Link Recorder Systems. This proposed TSO tells...performance standards (MPS) their Data-Link Recorder Systems must meet to be identified...Certification Service, Aircraft Engineering Division, Avionics...

2005-11-28

 
 
 
 
241

Development of EPICS package for small systems  

International Nuclear Information System (INIS)

EPICS is a control software toolkit, which was developed for large accelerators. The original EPICS assumes to use VME-bus computers and a commercial license of a real-time operating system (VxWorks). However, recent EPICS (version 3.14) can run on many operating system, such as Linux. Thus, EPICS can be introduced at a considerably lower cost than before. We are developing a customized EPICS package, miniEPICS, for small-scale accelerators and experiments. In this paper, we report on the development status of miniEPICS. (author)

242

Nursing Nomenclature and Classification System Development  

Directory of Open Access Journals (Sweden)

Full Text Available Classification is a rather new idea in nursing. It began as a movement to develop a language that would describe the clinical judgments made by nurses. There was great support by clinicians for describing problems that nurses are educated and licensed to treat which are not in medical language systems. Currently there are major efforts nationally and internationally to develop a nursing language system that includes nursing diagnoses, interventions and outcomes. These are the basic elements in a nursing classification for practice, minimum data set for health statistics, in costing out patient care, developing computerized patient records, and for education and research.

Gordon, M

1998-09-01

243

Development of cask and transportation system  

International Nuclear Information System (INIS)

The major goal of this project is to establish the safe transport system and obtain the necessary data for cask development by during research work for the design and safety test of shipping cask. The analysis technique using computer code for design has been studied in the field of structure, thermal and shielding analysis in this study. And also the test and measurement technology was developed for the measuring system of drop and fire test. It is expected that research activity ensured in this job will enable us to ultilize the basic data for the cask development. (Author)

244

Development of diagnostic system for JT-60 ICRF heating system  

Energy Technology Data Exchange (ETDEWEB)

The ion cyclotron range of frequencies (ICRF) heating system has been operated for eleven years since its completion. Recently, rate of troubles caused by aged deterioration of main components in the heating system is increasing year by year. To keep high availability of the heating system under such conditions and to proceed effective ICRF experiments, a usual checking system to make its performance sure or a rapid trouble shooting when troubles occurred, are required. So we have designed and developed a the diagnostic system which can provide an easy testing of various functions of the ICRF heating system without serious downtime. It was demonstrated that the diagnostic system developed is very useful for the trouble shooting and the various tests and adjustments. (author)

Yokokura, Kenji; Moriyama, Shinichi; Terakado, Masayuki [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment

1997-09-01

245

SNAP-8 electrical generating system development program  

Science.gov (United States)

The SNAP-8 program has developed the technology base for one class of multikilowatt dynamic space power systems. Electrical power is generated by a turbine-alternator in a mercury Rankine-cycle loop to which heat is transferred and removed by means of sodium-potassium eutectic alloy subsystems. Final system overall criteria include a five-year operating life, restartability, man rating, and deliverable power in the 90 kWe range. The basic technology was demonstrated by more than 400,000 hours of major component endurance testing and numerous startup and shutdown cycles. A test system, comprised of developed components, delivered up to 35 kWe for a period exceeding 12,000 hours. The SNAP-8 system baseline is considered to have achieved a level of technology suitable for final application development for long-term multikilowatt space missions.

1971-01-01

246

System model development for nuclear thermal propulsion  

Energy Technology Data Exchange (ETDEWEB)

A critical enabling technology in the evolutionary development of nuclear thermal propulsion (NTP) is the ability to predict the system performance under a variety of operating conditions. This is crucial for mission analysis and for control subsystem testing as well as for the modeling of various failure modes. Performance must be accurately predicted during steady-state and transient operation, including startup, shutdown and post operation cooling. The development and application of verified and validated system models has the potential to reduce the design, testing, cost and time required for the technology to reach flight-ready status. Since October 1991, the US Department of Energy (DOE), Department of Defense (DOD) and NASA have initiated critical technology development efforts for NTP systems to be used on Space Exploration Initiative (SEI) missions to the Moon and Mars. This paper presents the strategy and progress of an interagency NASA/DOE/DOD team for NTP system modeling.

Hannan, N.A. [Argonne National Lab., IL (United States); Worley, B.A. [Oak Ridge National Lab., TN (United States); Walton, J.T. [National Aeronautics and Space Administration, Cleveland, OH (United States). Lewis Research Center; Perkins, K.R. [Brookhaven National Lab., Upton, NY (United States); Buksa, J.J. [Los Alamos National Lab., NM (United States); Dobranich, D. [Sandia National Labs., Albuquerque, NM (United States)

1992-11-01

247

System model development for nuclear thermal propulsion  

Science.gov (United States)

A critical enabling technology in the evolutionary development of nuclear thermal propulsion (NTP) is the ability to predict the system performance under a variety of operating conditions. This is crucial for mission analysis and for control subsystem testing as well as for the modeling of various failure modes. Performance must be accurately predicted during steady-state and transient operation, including startup, shutdown and post operation cooling. The development and application of verified and validated system models has the potential to reduce the design, testing, cost and time required for the technology to reach flight-ready status. Since October 1991, the US Department of Energy (DOE), Department of Defense (DOD) and NASA have initiated critical technology development efforts for NTP systems to be used on Space Exploration Initiative (SEI) missions to the Moon and Mars. This paper presents the strategy and progress of an interagency NASA/DOE/DOD team for NTP system modeling.

Hannan, Nelson A.; Worley, Brian A.; Walton, James T.; Perkins, Ken R.; Buska, John J.; Dobranich, Dean

1992-08-01

248

Development of an automatic pipeline scanning system  

International Nuclear Information System (INIS)

Pressure pipe inspection in nuclear power plants is one of the mandatory regulation items. Comparing to manual ultrasonic inspection, automatic inspection has the benefits of more accurate and reliable inspection results and reduction of radiation disposal. final object of this project is to develop an automatic pipeline inspection system of pressure pipe welds in nuclear power plants. We developed a pipeline scanning robot with four magnetic wheels and 2-axis manipulator for controlling ultrasonic transducers, and developed the robot control computer which controls the robot to navigate along inspection path exactly. We expect our system can contribute to reduction of inspection time, performance enhancement, and effective management of inspection results. The system developed by this project can be practically used for inspection works after field tests. (author)

249

Development of an automatic pipeline scanning system  

Energy Technology Data Exchange (ETDEWEB)

Pressure pipe inspection in nuclear power plants is one of the mandatory regulation items. Comparing to manual ultrasonic inspection, automatic inspection has the benefits of more accurate and reliable inspection results and reduction of radiation disposal. final object of this project is to develop an automatic pipeline inspection system of pressure pipe welds in nuclear power plants. We developed a pipeline scanning robot with four magnetic wheels and 2-axis manipulator for controlling ultrasonic transducers, and developed the robot control computer which controls the robot to navigate along inspection path exactly. We expect our system can contribute to reduction of inspection time, performance enhancement, and effective management of inspection results. The system developed by this project can be practically used for inspection works after field tests. (author)

Kim, Jae H.; Lee, Jae C.; Moon, Soon S.; Eom, Heung S.; Choi, Yu R

1999-11-01

250

Development of minimally invasive surgery systems  

International Nuclear Information System (INIS)

This review describes the minimally invasive surgery systems developed by the Hitachi group in cooperation with some Japanese universities. Those systems are ''intelliOpe'', a micromanipulator system and ''Naviot''. intelliOpe'', which was developed in cooperation with Tokyo Women's Medical University, is an operation room system with an open MRI equipment by which the image information is available during surgery. The system started from March 2000 and was adopted for 166 brain tumor patients until May 2003. The mean and whole extirpation rates were 91% and 39% respectively, while whole extirpation rate in Japan is 8%. The micromanipulator system for the brain surgery was developed in cooperation with Shinshu University. It consists of 3 micromanipulators and an endoscope, and has been found useful after the first clinical use in August 2002. ''Naviot'' is a laparoscopic manipulator system with a five-bar linkage mechanism recently developed in cooperation with Tokyo University and Kyushu University. ''Naviot'' made it possible for the surgeons to change endoscopic sites easily and safely. As a Hitachi product, ''Naviot'' has been practically used for 51 cases in 16 hospitals until June 2003. (N.I.)

251

System model development for nuclear thermal propulsion  

International Nuclear Information System (INIS)

A critical enabling technology in the evolutionary development of nuclear thermal propulsion (NTP) is the ability to predict the system performance under a variety of operating conditions. This is crucial for mission analysis and for control subsystem testing as well as for the modeling of various failure modes. Performance must be accurately predicted during steady-state and transient operation, including startup, shutdown, and post operation cooling. The development and application of verified and validated system models has the potential to reduce the design, testing, and cost and time required for the technology to reach flight-ready status. Since Oct. 1991, the U.S. Department of Energy (DOE), Department of Defense (DOD), and NASA have initiated critical technology development efforts for NTP systems to be used on Space Exploration Initiative (SEI) missions to the Moon and Mars. This paper presents the strategy and progress of an interagency NASA/DOE/DOD team for NTP system modeling. It is the intent of the interagency team to develop several levels of computer programs to simulate various NTP systems. The first level will provide rapid, parameterized calculations of overall system performance. Succeeding computer programs will provide analysis of each component in sufficient detail to guide the design teams and experimental efforts. The computer programs will allow simulation of the entire system to allow prediction of the integrated performance. An interagency team was formed for this task to use the best capabilities available and to assure appropriate peer review

252

The development of ZPRL digital control system  

International Nuclear Information System (INIS)

Zero Power Reactor at Lung-Tan (ZPRL) is a small open-pool type research reactor located at Lung-Tan, Taiwan. The reactor achieved its first criticality in 1971. An analog control system has been used for almost over 20 years and the power regulating function is found gradually out of order. Therefore, we decided to develop a digital control system to replace the existing analog one. A prototype system has been developed and under on-line test now. The proposed ZPRL digital control system consists of three personal computers. These computers are used as (1) operator console, (2) data acquisition and control system, and (3) auxiliary and backup system. The operator console contains all the man-machine interface functions in the form of graphic display. The data acquisition and control system converts the analog signals into digital ones and feeds to the other two computers. The auxiliary and backup system normally emulates a strip chart recorder for the linear and logarithmic neutron powers and also acts as a transient recorder to keep the trace of the operating conditions on demand or when the reactor scrams. On-line test shows that the system does assure a satisfactory performance. It is not only as good as the analog system but also has the advantages of flexibility, testibility, and a user friendly man-machine interface. (author)

253

???????????? Evolutional Development of Library Information Systems  

Directory of Open Access Journals (Sweden)

Full Text Available ???????????????????????????????,?????????,???????????????????????????,????????????????????????????????Google??????????????????????????,?????????,?????????????,????4?14??????,?????????????,?????????????????????????????????????????????????????????????????????12?????????????Library information systems are an essential tool for libraries to acquire and organize information resources to deliver services to users. With advancement of information technologies, library information systems have also evolved from card catalogue into diverse ones, such as integrated library system, elec- tronic resource management system, Amazon.com and Google Books. This article aims to review the historical development of library information systems as a basis to explore the future landscape of library information systems. Case study is adopted as research methodology to analyze fourteen library informa- tion systems. Furthermore, research findings and discussions are organized in the following points: type, granularity, boundary, organization and aggrega- tion of object, and representation of information resources, as well as software implementation, social OPAC, software design, operation model, and access.

Hong-Chu Huang

2010-06-01

254

Development of a PSA information database system  

International Nuclear Information System (INIS)

The need to develop the PSA information database for performing a PSA has been growing rapidly. For example, performing a PSA requires a lot of data to analyze, to evaluate the risk, to trace the process of results and to verify the results. PSA information database is a system that stores all PSA related information into the database and file system with cross links to jump to the physical documents whenever they are needed. Korea Atomic Energy Research Institute is developing a PSA information database system, AIMS (Advanced Information Management System for PSA). The objective is to integrate and computerize all the distributed information of a PSA into a system and to enhance the accessibility to PSA information for all PSA related activities. This paper describes how we implemented such a database centered application in the view of two areas, database design and data (document) service

255

Environmental development plan: geothermal energy systems  

Energy Technology Data Exchange (ETDEWEB)

To ensure that environmental, health, and safety (EH and S) considerations are addressed adequately in the technology decision making process, the Environmental Development Plan (EDP) identifies and evaluates EH and S concerns; defines EH and S research and related assessments to examine or resolve the concerns; provides a coordinated schedule with the technology program for required EH and S research and developement; and indicates the timing for Environmental Assessments, Environmental Impact Statements, Environmental Readiness Documents, and Safety Analysis Reports. This EDP for geothermal energy systems covers all current and planned activities of the DOE Geothermal Energy Systems. Hydrothermal convection systems, geopressured systems, and hot-dry-rock systems are covered. Environmental concerns and requirements for resolution of these concerns are discussed at length. (MHR)

1979-08-01

256

Development of a change management system  

Science.gov (United States)

The complexity and interdependence of software on a computer system can create a situation where a solution to one problem causes failures in dependent software. In the computer industry, software problems arise and are often solved with 'quick and dirty' solutions. But in implementing these solutions, documentation about the solution or user notification of changes is often overlooked, and new problems are frequently introduced because of insufficient review or testing. These problems increase when numerous heterogeneous systems are involved. Because of this situation, a change management system plays an integral part in the maintenance of any multisystem computing environment. At the NASA Ames Advanced Computational Facility (ACF), the Online Change Management System (OCMS) was designed and developed to manage the changes being applied to its multivendor computing environment. This paper documents the research, design, and modifications that went into the development of this change management system (CMS).

Parks, Cathy Bonifas

1993-01-01

257

The Guided System Development Framework: Modeling and Verifying Communication Systems  

DEFF Research Database (Denmark)

In a world that increasingly relies on the Internet to function, application developers rely on the implementations of protocols to guarantee the security of data transferred. Whether a chosen protocol gives the required guarantees, and whether the implementation does the same, is usually unclear. The Guided System Development framework contributes to more secure communication systems by aiding the development of such systems. The framework features a simple modelling language, step-wise refinement from models to implementation, interfaces to security verification tools, and code generation from the verified specification. The refinement process carries thus security properties from the model to the implementation. Our approach also supports verification of systems previously developed and deployed. Internally, the reasoning in our framework is based on the Beliefs and Knowledge tool, a verification tool based on belief logics and explicit attacker knowledge.

Carvalho Quaresma, Jose Nuno; Probst, Christian W.

2014-01-01

258

Toward a Cooperative Experimental System Development Approach  

DEFF Research Database (Denmark)

This chapter represents a step towards the establishment of a new system development approach, called Cooperative Experimental System Development (CESD). CESD seeks to overcome a number of limitations in existing approaches: specification oriented methods usually assume that system design can be based solely on observation and detached reflection; prototyping methods often have a narrow focus on the technical construction of various kinds of prototypes; Participatory Design techniques—including the Scandinavian Cooperative Design (CD) approaches—seldom go beyond the early analysis/design activities of development projects. In contrast, the CESD approach is characterized by its focus on: active user involvement throughout the entire development process; prototyping experiments closely coupled to work-situations and use-scenarios; transforming results from early cooperative analysis/design to targeted object oriented design, specification, and realisation; and design for tailorability. The emerging CESD approach is based on several years of experience in applying cooperative analysis and design techniques in projects developing general, tailorable software products. The CESD approach is, however, not limited to this development context, it may be applied for in-house or contract development as well. In system development, particularly in cooperative and experimental system development, we argue that it is necessary to analytically separate the abstract concerns, e.g. analysis, design, and realisation from concrete activities and techniques. Thus we introduce a CESD model which provides a framework for handling this separation and at the same time makes it possible to identify and discuss the rich variety of relationships among concrete activities and the main concerns.

GrØnbæk, Kaj; Kyng, Morten

1997-01-01

259

Towed ADCP system to be developed  

Science.gov (United States)

A towed Acoustic Doppler Current Profiling (ADCP) system is being developed in a joint effort by ENDECO/YSI, Inc., and RD Instruments. The goal is to mount direct-reading or self-contained ADCPs in a towed system. The latter is planned to consist of a 6-foot V-fin with pod and cable/fairing. The prototype system is expected to undergo sea trials in mid 1991. Although the vehicle will be initially designed for towing at shallow depths, a deep-towed system is planned to be designed eventually.

260

Information Systems Development Methodolgies in Developing Higher Education  

Directory of Open Access Journals (Sweden)

Full Text Available Studies concerned with the status of Information Systems Development Methodologies usage in many developing countries including the factors that influence and motivate their use, current trends, difficulties, and barriers to adoption are lacking, especially within the higher education sector. This paper examines these identified gaps in a developing country, namely the United Arab Emirates. The initial findings reveal that there is limited knowledge and understanding of the concept of ISDM in federal higher education institutions in the UAE. This is reflected in the quality of the software products being developed and released. However, the analysed data also reveals a trend whereby federal higher education institutions in the UAE are gradually moving towards increased ISDM adoption and deployment.

Adam Marks

2012-02-01

 
 
 
 
261

Application of Three-Class ROC Analysis to Task-Based Image Quality Assessment of Simultaneous Dual-Isotope Myocardial Perfusion SPECT (MPS)  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The diagnosis of cardiac disease using dual-isotope myocardial perfusion SPECT (MPS) is based on the defect status in both stress and rest images, and can be modeled as a three-class task of classifying patients as having no, reversible, or fixed perfusion defects. Simultaneous acquisition protocols for dual-isotope MPS imaging have gained much interest due to their advantages including perfect registration of the 201Tl and 99mTc images in space and time, increased patient comfort, and higher...

He, Xin; Song, Xiyun; Frey, Eric C.

2008-01-01

262

Clover development during spaceflight: A model system  

Science.gov (United States)

The development of legume root nodules was studied as a model system for the examination of gravitational effects on plant root development. In order to examine whether rhizobial association with clover roots can be achieved in microgravity, experiments were performed aboard the KC-135 parabolic aircraft and aboard the sounding rocket mission Consort 3. Binding of rhizobia to roots and the initial stages of root nodule development successfully occurred in microgravity. Seedling germination experiments were performed in the sliding block device, the Materials Dispersion Apparatus, aboard STS-37. When significant hydration of the seeds was achieved, normal rates of germination and seedling development were observed.

Guikema, James A.; Debell, Lynnette; Paulsen, Avelina; Spooner, Brian S.; Wong, Peter P.

1994-08-01

263

Hydrogen storage and delivery system development  

Energy Technology Data Exchange (ETDEWEB)

Hydrogen storage and delivery is an important element in effective hydrogen utilization for energy applications and is an important part of the FY1994-1998 Hydrogen Program Implementation Plan. The purpose of this project is to develop a platform for the engineering evaluation of hydrogen storage and delivery systems with an added focus on lightweight hydride utilization. Hybrid vehicles represent the primary application area of interest, with secondary interests including such items as existing vehicles and stationary uses. The near term goal is the demonstration of an internal combustion engine/storage/delivery subsystem. The long term goal is optimization of storage technologies for both vehicular and industrial stationary uses. In this project an integrated approach is being used to couple system operating characteristics to hardware development. A model has been developed which integrates engine and storage material characteristics into the design of hydride storage and delivery systems. By specifying engine operating parameters, as well as a variety of storage/delivery design features, hydride bed sizing calculations are completed. The model allows engineering trade-off studies to be completed on various hydride material/delivery system configurations. A more generalized model is also being developed to allow the performance characteristics of various hydrogen storage and delivery systems to be compared (liquid, activated carbon, etc.). Many of the features of the hydride storage model are applicable to the development of this more generalized model.

Handrock, J.L.; Wally, K.; Raber, T.N. [Sandia National Labs., Livermore, CA (United States)

1995-09-01

264

NASA Redox Storage System Development Project  

Science.gov (United States)

The Redox Storage System Technology Project was jointly supported by the U.S. Department of Energy and NASA. The objectives of the project were to develop the Redox flow battery concept and to probe its technical and economic viability. The iron and chromium redox couples were selected as the reactants. Membranes and electrodes were developed for the original mode of operating at 25 C with the reactants separated by an ion-exchange membrane. Analytical capabilities and system-level operating concepts were developed and verified in a 1-kW, 13-kWh preprototype system. A subsequent change was made in operating mode, going to 65 C and using mixed reactants. New membranes and a new electrode catalyst were developed, resulting in single cell operation as high as 80 mA/sq cm with energy efficiencies greater than 80 percent. Studies indicate a likely system cost of about $75/kWh. Standard Oil of Ohio (Sohio) has undertaken further development of the Redox system. An exclusive patent license was obtained from NASA by Sohio. Transfer of Redox technology to Sohio is supported by the NASA Technology Utilization Office.

Hagedorn, N. H.

1984-10-01

265

An INTEL 8080 microprocessor development system  

International Nuclear Information System (INIS)

The INTEL 8080 has become one of the two most widely used microprocessors at CERN, the other being the MOTOROLA 6800. Even thouth this is the case, there have been, to date, only rudimentary facilities available for aiding the development of application programs for this microprocessor. An ideal development system is one which has a sophisticated editing and filing system, an assembler/compiler, and access to the microprocessor application. In many instances access to a PROM programmer is also required, as the application may utilize only PROMs for program storage. With these thoughts in mind, an INTEL 8080 microprocessor development system was implemented in the Proton Synchrotron (PS) Division. This system utilizes a PDP 11/45 as the editing and file-handling machine, and an MSC 8/MOD 80 microcomputer for assembling, PROM programming and debugging user programs at run time. The two machines are linked by an existing CAMAC crate system which will also provide the means of access to microprocessor applications in CAMAC and the interface of the development system to any other application. (Auth.)

266

Development of Solar Powered Irrigation System  

Science.gov (United States)

Development of a solar powered irrigation system has been discussed in this paper. This system would be SCADA-based and quite useful in areas where there is plenty of sunshine but insufficient water to carry out farming activities, such as rubber plantation, strawberry plantation, or any plantation, that requires frequent watering. The system is powered by solar system as a renewable energy which uses solar panel module to convert Sunlight into electricity. The development and implementation of an automated SCADA controlled system that uses PLC as a controller is significant to agricultural, oil and gas monitoring and control purpose purposes. In addition, the system is powered by an intelligent solar system in which solar panel targets the radiation from the Sun. Other than that, the solar system has reduced energy cost as well as pollution. The system is equipped with four input sensors; two soil moisture sensors, two level detection sensors. Soil moisture sensor measures the humidity of the soil, whereas the level detection sensors detect the level of water in the tank. The output sides consist of two solenoid valves, which are controlled respectively by two moistures sensors.

Abdelkerim, A. I.; Sami Eusuf, M. M. R.; Salami, M. J. E.; Aibinu, A.; Eusuf, M. A.

2013-12-01

267

Cryogenic Propellant Feed System Analytical Tool Development  

Science.gov (United States)

The Propulsion Systems Branch at NASA s Lyndon B. Johnson Space Center (JSC) has developed a parametric analytical tool to address the need to rapidly predict heat leak into propellant distribution lines based on insulation type, installation technique, line supports, penetrations, and instrumentation. The Propellant Feed System Analytical Tool (PFSAT) will also determine the optimum orifice diameter for an optional thermodynamic vent system (TVS) to counteract heat leak into the feed line and ensure temperature constraints at the end of the feed line are met. PFSAT was developed primarily using Fortran 90 code because of its number crunching power and the capability to directly access real fluid property subroutines in the Reference Fluid Thermodynamic and Transport Properties (REFPROP) Database developed by NIST. A Microsoft Excel front end user interface was implemented to provide convenient portability of PFSAT among a wide variety of potential users and its ability to utilize a user-friendly graphical user interface (GUI) developed in Visual Basic for Applications (VBA). The focus of PFSAT is on-orbit reaction control systems and orbital maneuvering systems, but it may be used to predict heat leak into ground-based transfer lines as well. PFSAT is expected to be used for rapid initial design of cryogenic propellant distribution lines and thermodynamic vent systems. Once validated, PFSAT will support concept trades for a variety of cryogenic fluid transfer systems on spacecraft, including planetary landers, transfer vehicles, and propellant depots, as well as surface-based transfer systems. The details of the development of PFSAT, its user interface, and the program structure will be presented.

Lusby, Brian S.; Miranda, Bruno M.; Collins, Jacob A.

2011-01-01

268

HAMMER COURSEWARE MANAGEMENT SYSTEM (CMS) SYSTEM DEVELOPMENT & IMPLEMENTATION  

Energy Technology Data Exchange (ETDEWEB)

HAMMER Courseware Management System (HAMMERCMS) is the official name of the system Fluor Hanford, Inc., uses to facilitate development of, deliver, and track training presented in some electronic form (mainly, web-based training) to Hanford Site employees, subcontractors, and vendors.

GARDNER, P.R.

2006-04-28

269

Solar-Electric Dish Stirling System Development  

Energy Technology Data Exchange (ETDEWEB)

Electrical power generated with the heat from the sun, called solar thermal power, is produced with three types of concentrating solar systems - trough or line-focus systems; power towers in which a centrally-located thermal receiver is illuminated with a large field of sun-tracking heliostats; and dish/engine systems. A special case of the third type of system, a dish/Stirling system, is the subject of this paper. A dish/Stirling system comprises a parabolic dish concentrator, a thermal receiver, and a Stirling engine/generator located at the focus of the dish. Several different dish/Stirling systems have been built and operated during the past 15 years. One system claims the world record for net conversion of solar energy to electric power of 29.4%; and two different company`s systems have accumulated thousands of hours of on-sun operation. Due to de-regulation and intense competition in global energy markets as well as the immaturity of the technology, dish/Stirling systems have not yet found their way into the marketplace. This situation is changing as solar technologies become more mature and manufacturers identify high-value niche markets for their products. In this paper, I review the history of dish/Stirling system development with an emphasis on technical and other issues that directly impact the Stirling engine. I also try to provide some insight to the opportunities and barriers confronting the application of dish/Stirling in power generation markets.

Mancini, T.R.

1997-12-31

270

Development of Digitex premier digital angiographic systems  

Energy Technology Data Exchange (ETDEWEB)

The technique of interventional radiology has come to be widely utilized in the field of angiography. This has brought forth a strong demand that digital angiographic systems provide high efficiency in patient examinations and high level of interventional support. This report refers to our newly developed Digitex Premier Series digital angiographic systems, designed to meet the above demands. The new systems utilize a high-speed, wide-range C-arm system, a high-resolution image intensifier, a fluid-lubricant X-ray tube, and a digital image processing system, in order to ensure high patient examination efficiency. Their IVR (interventional radiology)-Master bed-side image controller further enhances the efficiency of patient examinations, and also, their CAT (comfortable angio terminal) and FMC (file management console) improve the patient examination throughput and diagnostic workflow of the systems. (author)

Miura, Yoshiaki; Miura, Yusuke; Goto, Keiichi; Imanishi, Tetsuo; Miyamoto, Wataru [Shimadzu Corp., Medical Systems Division, Kyoto (Japan)

2003-06-01

271

Development of Digitex premier digital angiographic systems  

International Nuclear Information System (INIS)

The technique of interventional radiology has come to be widely utilized in the field of angiography. This has brought forth a strong demand that digital angiographic systems provide high efficiency in patient examinations and high level of interventional support. This report refers to our newly developed Digitex Premier Series digital angiographic systems, designed to meet the above demands. The new systems utilize a high-speed, wide-range C-arm system, a high-resolution image intensifier, a fluid-lubricant X-ray tube, and a digital image processing system, in order to ensure high patient examination efficiency. Their IVR (interventional radiology)-Master bed-side image controller further enhances the efficiency of patient examinations, and also, their CAT (comfortable angio terminal) and FMC (file management console) improve the patient examination throughput and diagnostic workflow of the systems. (author)

272

Development of compact CCTV surveillance system 'COSMOS'  

International Nuclear Information System (INIS)

The Compact Surveillance Monitoring System (COSMOS) has been developed as a compact, simple, highly reliable CCTV surveillance system. The system is intended to provide a replacement for the IAEA Twin Minolta Film Camera System. The system consists of a recording unit and a set up/review unit. The recording unit consisting of a CCD camera module, a 8 mm VTR unit, a controller module and a power unit is enclosed in a tamper-indicating housing. The VTR module of very low power consumption is specially designed for COSMOS capable of battery operation. The system can be operated for three months either by battery where mains power is not readily available or by AC powers. The prototype of COSMOS was completed in 1989 and the field-evaluation model will be tested for acceptance at the IAEA from August 1990. (author)

273

Thermal performance advisor expert system development  

International Nuclear Information System (INIS)

In recent years the electric industry has developed an increased interest in improving efficiency of nuclear power plants. EPRI has embarked upon a research project RP2407, Nuclear Plant Performance Improvements which is designed to address needs in this area. One product of this project has been the Thermal Performance Diagnostic Manual for Nuclear Power Plants (NP-4990P). The purpose of this manual is to provide engineering personnel at nuclear power plants with a consistent way in which to identify thermal performance problems. General Physics is also involved in the development of another computer system called Fossil Thermal Performance Advisor (FTPA) which helps operators improve performance for fossil power plants. FTPA is a joint venture between General Physics and New York State Electric and Gas Company. This paper describes both of these computer systems and uses the FTPA as an interesting comparison that illustrates the considerations required for the development of a computer system that effectively addresses the needs of the users

274

Development of the data acquisition system 'MORAINE'  

International Nuclear Information System (INIS)

This publication presents the software development of the data acquisition system 'MORAINE'. The distributed multiprocessor system is designed for the spectrometer SPHERE. The system consists of three VME processor modules, specialized FASTBUS modules, three personal computers (IBM PC) type networked with local Ethernet. The software is developed for three VME processor modules. It controls the reading of event fragments into VME processor modules and uses data block transfer via direct memory access, reconstructs the events, transfers data into the local network for on-line analysis and records data on external media for OFF-line analysis. The usage of the distributed computer system allows one to duplicate the efficiency of the spectrometer due to parallel reading event fragments. (author)

275

Developing Automatic Controllers for sprinkler irrigation systems  

Science.gov (United States)

The application of new technologies to the control and automation of irrigation processes is quickly gaining attention. The automation of irrigation execution (through irrigation controllers) is now widespread. However, the automatic generation and execution of irrigation schedules is receiving growing attention due to the possibilities offered by the telemetry/remote control systems currently being installed in collective pressurized networks. These developments can greatly benefit from the combination of irrigation system and crop models, and from the interaction with agrometeorological databases, hydraulic models of pressurized collective distribution networks, weather forecasts and management databases for water users associations. Prospects for the development of such systems in collective sprinkler irrigation systems are analyzed in this presentation. Additionally, experimental results are presented on the application of these concepts to a hydrant irrigating a solid-set irrigated maize field.

Playán, E.; Salvador, R.; Cavero, J.; López, C.; Lecina, S.; Zapata, N.

2012-04-01

276

Hydrogen storage and delivery system development: Analysis  

Energy Technology Data Exchange (ETDEWEB)

Hydrogen storage and delivery is an important element in effective hydrogen utilization for energy applications and is an important part of the FY1994-1998 Hydrogen Program Implementation Plan. This project is part of the Field Work Proposal entitled Hydrogen Utilization in Internal Combustion Engines (ICE). The goal of the Hydrogen Storage and Delivery System Development Project is to expand the state-of-the-art of hydrogen storage and delivery system design and development. At the foundation of this activity is the development of both analytical and experimental evaluation platforms. These tools provide the basis for an integrated approach for coupling hydrogen storage and delivery technology to the operating characteristics of potential hydrogen energy use applications. Results of the analytical model development portion of this project will be discussed. Analytical models have been developed for internal combustion engine (ICE) hybrid and fuel cell driven vehicles. The dependence of hydride storage system weight and energy use efficiency on engine brake efficiency and exhaust temperature for ICE hybrid vehicle applications is examined. Results show that while storage system weight decreases with increasing engine brake efficiency energy use efficiency remains relatively unchanged. The development, capability, and use of a recently developed fuel cell vehicle storage system model will also be discussed. As an example of model use, power distribution and control for a simulated driving cycle is presented. Model calibration results of fuel cell fluid inlet and exit temperatures at various fuel cell idle speeds, assumed fuel cell heat capacities, and ambient temperatures are presented. The model predicts general increases in temperature with fuel cell power and differences between inlet and exit temperatures, but under predicts absolute temperature values, especially at higher power levels.

Handrock, J.L. [Sandia National Labs., Livermore, CA (United States)

1996-10-01

277

Reactor alarm system development and application issues  

International Nuclear Information System (INIS)

The new hardware and software technologies, and the need in research reactors for assistance systems in operation and maintenance, have given an appropriate background to develop a computer based system named ''Reactor Alarm System'' (RAS). RAS is a software package, user oriented, with emphasis on production, experiments and maintenance goals. It is designed to run on distributed systems conformed with microcomputers under QNX operating system. RAS main features are: a) Alarm Panel Display; b) Alarm Page; c) Alarm Masking and Inhibition; d) Alarms Color and Attributes; e) Condition Classification; and f) Arrangement Presentation. RAS design allows it to be installed as a part of a computer based Supervision and Control System in new installations or retrofit existing reactor instrumentation systems. The analysis of human factors during development stage and successive user feedback from different applications, brought out several RAS improvements: a) Multiple-copy alarm summaries; b) Improved alarm handling; c) Extended dictionary; and d) Enhanced hardware availability. It has proved successful in providing new capabilities for operators, and also has shown the continuous increase of user-demands, reflecting the expectations placed today on computer-based systems. (author). 6 figs, 1 tabs

278

Developing an Information Security Management System  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The purpose of this thesis was to study development of an information security management system and study the resources and components, which combined create a functional information security management system. To reach the target objective, the thesis first examines the international and international legislation regarding information security. Secondly, the information security related international and national standards and frameworks are analyzed and compared. Finally the outcome of the...

Karjalainen, Mika

2014-01-01

279

Developing Digital Control System Centrifugal Pumping Unit  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Currently, the leading Russian oil companies engaged in the development of automatic control systems (ACS) oil equipment, to improve its efficiency. As an example of an object needed to optimize its work, a centrifugal pumping unit (CPU) can be specified. Frequency actuators provide an opportunity to run CPU in any algorithm, and many industrial controllers, are part of the automatic control system technological process (ACSTP), allow optimizing the operation of the centrifugal pumping unit a...

Safarini Osama

2011-01-01

280

Heatpipe power system and heatpipe bimodal system development status  

International Nuclear Information System (INIS)

The Heatpipe Power System (HPS) is a potential, near-term, low-cost space fission power system. The Heatpipe Bimodal System (HBS) is a potential, near-term, low-cost space fission power and/or propulsion system. Both systems will be composed of independent modules, and all components use existing technology and operate within the existing database. The HPS and HBS have relatively few system integration issues; thus, the successful development of a module is a significant step toward verifying system feasibility and performance estimates. A prototypic HPS module was fabricated, and initial testing was completed in April 1997. All test objectives were accomplished, demonstrating the basic feasibility of the HPS. Fabrication of an HBS module is underway, and testing should begin in early 1998. copyright 1998 American Institute of Physics

 
 
 
 
281

Development of automatic laser welding system  

International Nuclear Information System (INIS)

Laser are a new production tool for high speed and low distortion welding and applications to automatic welding lines are increasing. IHI has long experience of laser processing for the preservation of nuclear power plants, welding of airplane engines and so on. Moreover, YAG laser oscillators and various kinds of hardware have been developed for laser welding and automation. Combining these welding technologies and laser hardware technologies produce the automatic laser welding system. In this paper, the component technologies are described, including combined optics intended to improve welding stability, laser oscillators, monitoring system, seam tracking system and so on. (author)

282

Developing a Moving Objects Management System  

Directory of Open Access Journals (Sweden)

Full Text Available The aim of this study are to evaluate the current states of the Moving Objects (MO systems and extend them to support tracking, indexing, modeling and visual querying of public transportation buses. To evaluate the system, the queries posed by fleet management companies are selected. The results showed its superior functionalities through text-based and visual queries. This study will contribute to the establishment of a Moving Objects Management System (MOMS with modest expenditure and a short development period and which is independent of the database used.

Y.E. Ghajary

2008-01-01

283

Development of liquid propulsion systems in ISRO  

Energy Technology Data Exchange (ETDEWEB)

A development history is presented for ISRO's monopropellant and bipropellant liquid-fuel rocket propulsion systems. These have included bipropellant engines employing hypergolic propellants and ablative chambers that have been employed as both single stages and multistage system sustainer stages. The monopropellant thrusters have found application in reaction-control systems for satellites and launch vehicles. Currently, film-cooled, regeneratively-cooled, and radiation-cooled engines are undergoing tests for application aboard the Polar Satellite Launch Vehicle, as well as for apogee propulsion of the Insat-II.

Muthunayagam, A.E.

1988-01-01

284

Progress in optical strain measurement system development  

Science.gov (United States)

A laser speckle strain measurement system has been built and tested for the NASA Lewis Research Center. The system is based on a speckle shift technique, which automatically corrects for error due to rigid body motion, and provides a near real time measure of strain. The first stage of a multiphase effort to develop an optical strain gauge capable of mapping in two dimensions the strain on the surface of a hot specimen is discussed. The objectives of this first phase have been to provide a noncontact, one-dimensional, differential strain gauge for experimental purposes, and to determine the maximum open air temperature limit of the system.

Lant, Christian T.; Qaqish, Walid

1987-01-01

285

Development and implementation of integrated management system  

International Nuclear Information System (INIS)

Risk Engineering Ltd is a private Bulgarian company in the field of scientific technical consultancy and engineering services, established in 1990. The aim of this report is to present the experience of Risk Engineering Ltd. in the development, implementation and operation of an integrated management system. The process of implementation of the system was completed at the end of 2011. In January 2012, the Risk Engineering Integrated Management System was certified by Lloyd's Register for compliance with standards ISO 9001:2008, ISO 140001:2004 and BS OHSAS 18001:2007

286

Proposed tokamak poloidal field system development program  

International Nuclear Information System (INIS)

A program is proposed to develop poloidal field components for TNS and EPR size tokamak devices and to test these components in realistic circuits. Emphasis is placed upon the development of the most difficult component, the superconducting ohmic-heating coil. Switches must also be developed for testing the coils, and this switching technology is to be extended to meet the requirements for the large scale tokamaks. Test facilities are discussed; power supplies, including a homopolar to drive the coils, are considered; and poloidal field systems studies are proposed

287

Proposed tokamak poloidal field system development program  

Energy Technology Data Exchange (ETDEWEB)

A program is proposed to develop poloidal field components for TNS and EPR size tokamak devices and to test these components in realistic circuits. Emphasis is placed upon the development of the most difficult component, the superconducting ohmic-heating coil. Switches must also be developed for testing the coils, and this switching technology is to be extended to meet the requirements for the large scale tokamaks. Test facilities are discussed; power supplies, including a homopolar to drive the coils, are considered; and poloidal field systems studies are proposed.

Rogers, J.D.; Vogel, H.F.; Warren, R.W.; Weldon, D.M.

1977-05-01

288

Developing aircraft photonic networks for airplane systems  

DEFF Research Database (Denmark)

Achieving affordable high speed fiber optic communication networks for airplane systems has proved to be challenging. In this paper we describe a summary of the EU Framework 7 project DAPHNE (Developing Aircraft Photonic Networks). DAPHNE aimed to exploit photonic technology from terrestrial communications networks, and then develop and optimize aircraft photonic networks to take advantage of the potential cost savings. The main areas of emphasis were on: multiplexing networks; providing standard components; simplifying installation; and reducing through life support costs. DAPHNE (fifteen partners from seven nations) finished in February 2013; and was supported by the European Commission?s Seventh Framework Programme, although the consortium members are continuing with in-house developments.

White, Henry J. BAE Systems Ltd.

2013-01-01

289

Development of Testing Environment for Embedded Systems  

Directory of Open Access Journals (Sweden)

Full Text Available Quality is the life of embedded systems, and thetesting is a basic guarantee for stable and reliable operation ofthe embedded systems. Testing is an important part in thedevelopment of any system as it represents the ultimateverification and validation of specification, design and code.The goal of testing is to design a series of test cases that has thehighest likelihood of finding most of the errors with a minimumamount of time and effort. The techniques used to test theembedded systems provide systematic guidance for designingtests that exercise the internal logic of Embedded Systemcomponents and test the input and output domains of theprogram to uncover errors in program function, behavior andperformance. Simulation can be used as an alternative to theactual target system for a significant portion of the testingeffort, saving developers time and money, as well as increasingtest coverage and providing better debugging facilities, itbecomes much more necessary to construct embedded systemstesting environment.

Miss. Ashwini M. Motghare, Prof. Swapnili P. Karmore

2012-05-01

290

Development of a thermoluminescent personnel monitoring system  

International Nuclear Information System (INIS)

Thermoluminescent personnel monitoring system has been developed by the Division of Radiological Protection, Bhabha Atomic Research Centre (BARC), Bombay. The system is presently in use for estimation of personnel doses of radiation workers of BARC, other units of the Department of Atomic Energy, and Defence medical units in India. The report gives salient features of the TLD personnel monitoring system. The report discusses design considerations of thermoluminescent dosimetry (TLD) badge for measurement of X and ?;, ? personnel exposures, a filter combination to compensate for energy dependence of the TLD disc and angular dependence of the badge. The badge reader incorporates a semiautomatic mechanical arrangement wherein the TLD cards are read, raising the heater after positioning the TLD discs one by one. Various figures illustrate the mechanical layouts and electronics circuits used in the system. Periodic quality assurance check of the system which ensures a good reproducibility, is also described. (author)

291

Development of PLC-base thermometer system  

International Nuclear Information System (INIS)

In three power-supply buildings of J-PARC MR, we have used a room-temperature measuring system. However, present system becomes old and unstable. We have designed and installed a new PLC-based system instead. We adopted the same PLC series, Yokogawa F3RP61 and FA-M3R, which have been used in MR accelerator controls. There are 8 sensors at each building, thus, 24 sensors in total. Each sensor is scanned at 1-second interval. In addition, we developed (a) a user-friendly GUI for overviewing temperatures, (b) data archive system with Web-based retrieval, and so on. The new room-temperature measuring system has been in operation very successfully. (author)

292

Space Fission Propulsion System Development Status  

Science.gov (United States)

The world's first man-made self-sustaining fission reaction was achieved in 1942. Since then fission has been used to propel submarines, generate tremendous amounts of electricity, produce medical isotopes, and provide numerous other benefits to society. Fission systems operate independently of solar proximity or orientation, and are thus well suited for deep space or planetary surface missions. In addition, the fuel for fission systems (enriched uranium) is virtually non-radioactive. The primary safety issue with fission systems is avoiding inadvertent system start. Addressing this issue through proper system design is straight-forward. Despite the relative simplicity and tremendous potential of space fission systems, the development and utilization of these systems has proven elusive. The first use of fission technology in space occurred 3 April 1965 with the US launch of the SNAP-10A reactor. There have been no additional US uses of space fission systems. While space fission systems were used extensively by the former Soviet Union, their application was limited to earth-orbital missions. Early space fission systems must be safely and affordably utilized if we are to reap the benefits of advanced space fission systems. NASA's Marshall Space Flight Center, working with Los Alamos National Laboratory (LANL), Sandia National Laboratories, and others, has conducted preliminary research related to a Safe Affordable Fission Engine (SAFE). An unfueled core has been fabricated by LANL, and resistance heaters used to verify predicted core thermal performance by closely mimicking heat from fission. The core is designed to use only established nuclear technology and be highly testable. In FY01 an energy conversion system and thruster will be coupled to the core, resulting in an 'end-to-end' nuclear electric propulsion demonstrator being tested using resistance heaters to closely mimic heat from fission. Results of the SAFE test program will be presented. The applicability of a SAFE-powered electric propulsion system to outer planet science missions will also be discussed.

Houts, M.; Van Dyke, M. K.; Godfroy, T. J.; Pedersen, K. W.; Martin, J. J.; Dickens, R.; Williams, E.; Harper, R.; Salvail, P.; Hrbud, I.

2001-01-01

293

Development of centrifugal contactor system in JNC  

International Nuclear Information System (INIS)

Japan Nuclear Cycle Development Institute (JNC) has been developing centrifugal contactors which are compact and high performance for solvent extraction process in industrial reprocessing plant. Centrifugal contactor has some advantages which are more compact, smaller holdup volume, and higher separation performance than conventional contactor such as mixer-settler or pulse column. It contributes to economic advantage and reduction of solvent waste. In addition, the compact contactor is easy to manage the critical safety, and the operation ratio for fuel treatment can be improved because of short start-up and shut-down time. Since 1985, JNC has been developing the centrifugal contactor and fundamental design was established for engineering scale hot test plant (RETF). The life time was evaluated by the result of endurance test, and system performance of multi-stages contactor on engineering scale was demonstrated. In addition, several advanced type contactors have been developing. This paper introduces the development of centrifugal contactor in JNC. (author)

294

Development of Human System Integration at NASA  

Science.gov (United States)

Human Systems Integration seeks to design systems around the capabilities and limitations of the humans which use and interact with the system, ensuring greater efficiency of use, reduced error rates, and less rework in the design, manufacturing and operational deployment of hardware and software. One of the primary goals of HSI is to get the human factors practitioner involved early in the design process. In doing so, the aim is to reduce future budget costs and resources in redesign and training. By the preliminary design phase of a project nearly 80% of the total cost of the project is locked in. Potential design changes recommended by evaluations past this point will have little effect due to lack of funding or a huge cost in terms of resources to make changes. Three key concepts define an effective HSI program. First, systems are comprised of hardware, software, and the human, all of which operate within an environment. Too often, engineers and developers fail to consider the human capacity or requirements as part of the system. This leads to poor task allocation within the system. To promote ideal task allocation, it is critical that the human element be considered early in system development. Poor design, or designs that do not adequately consider the human component, could negatively affect physical or mental performance, as well as, social behavior. Second, successful HSI depends upon integration and collaboration of all the domains that represent acquisition efforts. Too often, these domains exist as independent disciplines due to the location of expertise within the service structure. Proper implementation of HSI through participation would help to integrate these domains and disciplines to leverage and apply their interdependencies to attain an optimal design. Via this process domain interests can be integrated to perform effective HSI through trade-offs and collaboration. This provides a common basis upon which to make knowledgeable decisions. Finally, HSI must be considered early in the requirements development phase of system design and acquisition. This will provide the best opportunity to maximize return on investment (ROI) and system performance. HSI requirements must be developed in conjunction with capability ]based requirements generation through functional. HSI requirements will drive HSI metrics and embed HSI issues within the system design. After a system is designed, implementation of HSI oversights can be very expensive. An HSI program should be included as an integral part of a total system approach to vehicle and habitat development. This would include, but not limited to, workstation design, D&C development, volumetric analysis, training, operations, and human -robotic interaction. HSI is a necessary process for Human Space Flight programs to meet the Agency Human ]System standards and thus mitigate human risks to acceptable levels. NASA has been involved in HSI planning, procedures development, process, and implementation for many years, and has been building several internal and publicly accessible products to facilitate HSI fs inclusion in the NASA Systems Engineering Lifecycle. Some of these products include: NASA STD 3001 Volumes 1 and 2, Human Integration Design Handbook, NASA HSI Implementation Plan, NASA HSI Implementation Plan Templates, NASA HSI Implementation Handbook, and a 2 ]hour short course on HSI delivered as part of the NASA Space and Life Sciences Directorate Academy. These products have been created leveraging industry best practices and lessons learned from other Federal Government agencies.

Whitmore, Mihriban; McGuire, Kerry; Thompson, Shelby; Vos, Gordon

2012-01-01

295

Development of a safety parameter supervision system  

International Nuclear Information System (INIS)

This work is a report on the safety parameter supervision system developed by the Nuclear Engineering Program of COPPE/UFRJ. It is specially concerned with safety parameters of Angra-1 nuclear power plant as well as its computer network. (A.C.A.S.)

296

Teaching Information Systems Development via Process Variants  

Science.gov (United States)

Acquiring the knowledge to assemble an integrated Information System (IS) development process that is tailored to the specific needs of a project has become increasingly important. It is therefore necessary for educators to impart to students this crucial skill. However, Situational Method Engineering (SME) is an inherently complex process that…

Tan, Wee-Kek; Tan, Chuan-Hoo

2010-01-01

297

Recent developments of the ALPI control system  

International Nuclear Information System (INIS)

This paper presents recent developments of the control system for ALPI, the new superconducting linear accelerator that will begin to operate at L.N.L. next year. Both hardware and software architectures are described and some base choices are discussed. Results of tests performed in the last two years are also reported. (author)

298

MPACT Fast Neutron Multiplicity System Prototype Development  

Energy Technology Data Exchange (ETDEWEB)

This document serves as both an FY2103 End-of-Year and End-of-Project report on efforts that resulted in the design of a prototype fast neutron multiplicity counter leveraged upon the findings of previous project efforts. The prototype design includes 32 liquid scintillator detectors with cubic volumes 7.62 cm in dimension configured into 4 stacked rings of 8 detectors. Detector signal collection for the system is handled with a pair of Struck Innovative Systeme 16-channel digitizers controlled by in-house developed software with built-in multiplicity analysis algorithms. Initial testing and familiarization of the currently obtained prototype components is underway, however full prototype construction is required for further optimization. Monte Carlo models of the prototype system were performed to estimate die-away and efficiency values. Analysis of these models resulted in the development of a software package capable of determining the effects of nearest-neighbor rejection methods for elimination of detector cross talk. A parameter study was performed using previously developed analytical methods for the estimation of assay mass variance for use as a figure-of-merit for system performance. A software package was developed to automate these calculations and ensure accuracy. The results of the parameter study show that the prototype fast neutron multiplicity counter design is very nearly optimized under the restraints of the parameter space.

D.L. Chichester; S.A. Pozzi; J.L. Dolan; M.T. Kinlaw; S.J. Thompson; A.C. Kaplan; M. Flaska; A. Enqvist; J.T. Johnson; S.M. Watson

2013-09-01

299

Development of the Guardian environmental monitoring system  

International Nuclear Information System (INIS)

The report describes the Guardian Environmental Monitoring System, developed jointly by the CEGB's Berkeley Nuclear Laboratories (BNL) and GEC Energy Systems Limited (ESL). The basic battery operated instrument was developed by BNL for the measurement of any nuclear facility contribution to the overall environmental dose. It uses an energy compensated Geiger counter to provide a continuous record for over a month of dose rates from 1 ?R h-1 (10nGy h-1). Results are presented of initial development trials and of an intercomparison with the USA Environmental Measurement Laboratory. The Guardian system, however, was developed, not only to meet the CEGB requirements for a recording monitor, but also to meet the requirements of US Regulatory Commission Guide RG 1.97, introduced as a result of the accident at Three Mile Island. This system, by using two energy compensated Geiger counters has a range from 1?Rh-1 up to 10Rh-1 (approximately equal to 100mGyh-1), and the associated electronics provides automatic range changing, including fast response to ramp exposure rate changes, alarm and test facilities and telemetry by line or radio to a central station. (author)

300

Digital hydraulic valving system. [design and development  

Science.gov (United States)

The design and development are reported of a digital hydraulic valving system that would accept direct digital inputs. Topics include: summary of contractual accomplishments, design and function description, valve parameters and calculations, conclusions, and recommendations. The electrical control circuit operating procedure is outlined in an appendix.

1973-01-01

 
 
 
 
301

Development of DUMAS data processing system  

International Nuclear Information System (INIS)

In the field of nuclear experiments, the speed-up of data processing has been required recently along with the increase of the amount of data per event or the rate of event occurrence per unit time. In the DUMAS project of RCNP, the development of data processing system has been required, which can perform the high speed transfer and processing. The system should transfer the data of 5 multiwire proportional counters and other counters from the laboratory to the counting room at the rate of 1000 events every second, and also should perform considerably complex processes such as histogramming, particle identification, calculation of various polarizations as well as dumping to the secondary memory in the counting room. Furthermore, easy start-up, adjustment, inspection and maintenance and non-special hardware and software should be considered. A system presently being investigated for satisfying the above requirements is described. The main points are as follows: to employ CAMAC system for the interface with readout circuit, to transfer data between the laboratory and the counting room by converting the byte-serial transfer to the bit-serial optical fiber communication, and to unify the data processing computers to the PDP-11 family by connecting two miniature computers. Development of such a data processing system seems to be useful as an preparatory research for the development of NUMATRON measuring instruments. (Wakatsuki, Y.)

302

Development of a steam generator lancing system  

International Nuclear Information System (INIS)

It is recommended to clean steam generators of nuclear power plants during plant outages. Under normal operations, sludge is created and constantly accumulates in the steam generators. The constituents of this sludge are different depending on each power plant characteristics. The sludge of the Kori Unit 1 steam generator, for example, was found to be composed of 93% ferrous oxide, 3% carbon and 1% of silica oxide and nickel oxide each. The research to develop a lancing system that would remove sludge deposits from the tubesheet of a steam generator was started in 1998 by the Korea Electric Power Research Institute (KEPRI) of the Korea Electric Power Corporation (KEPCO). The first commercial domestic lancing system in Korea, and KALANS-I Lancing System, was completed in 2000 for Kori Unit 1 for cleaning the tubesheet of its Westinghouse Delta-60 steam generator. Thereafter, the success of the development and site implementation of the KALANS-I lancing system for YGN Units 1 and 2 and Ulchin Units 3 and 4 was also realized in 2004 for sludge removal at those sites. The upper bundle cleaning system for Westinghouse model F steam generators is now under development

303

Development of a steam generator lancing system  

Energy Technology Data Exchange (ETDEWEB)

It is recommended to clean steam generators of nuclear power plants during plant outages. Under normal operations, sludge is created and constantly accumulates in the steam generators. The constituents of this sludge are different depending on each power plant characteristics. The sludge of the Kori Unit 1 steam generator, for example, was found to be composed of 93% ferrous oxide, 3% carbon and 1% of silica oxide and nickel oxide each. The research to develop a lancing system that would remove sludge deposits from the tubesheet of a steam generator was started in 1998 by the Korea Electric Power Research Institute (KEPRI) of the Korea Electric Power Corporation (KEPCO). The first commercial domestic lancing system in Korea, and KALANS-I Lancing System, was completed in 2000 for Kori Unit 1 for cleaning the tubesheet of its Westinghouse Delta-60 steam generator. Thereafter, the success of the development and site implementation of the KALANS-I lancing system for YGN Units 1 and 2 and Ulchin Units 3 and 4 was also realized in 2004 for sludge removal at those sites. The upper bundle cleaning system for Westinghouse model F steam generators is now under development.

Jeong, Woo-Tae; Kim, Seok-Tae; Hong, Sung-Yull [Korea Electric Power Research Institute, Daejeon (Korea, Republic of)

2006-06-15

304

Development of technical information processing systems  

Energy Technology Data Exchange (ETDEWEB)

The major goal of this project is to develop a more efficient information management system by connecting the KAREI serials database which enable the users to access from their own laboratory facilities through KAREI-NET. The importance of this project is to make the serials information of KAERI easily accessible to users as valuable resources for R and D activities. The results of the project are as follows. (1) Development of the serials database and retrieval system enabled us to access to the serials holding information through KAERI-NET. (2) The database construction establishes a foundation for the management of 1,600 serials held in KAERI. (3) The system can be applied not only to KAERI but also to similar medium-level libraries. (Author).

Lee, Ji Ho; Kim, Tae Whan; Kim, Sun Ja; Kim, Young Min; Choi, Kwang; Oh, Joung Hun; Choung, Hyun Suk; Keum, Jong Yong; Yoo, An Na; Harn, Deuck Haing; Choun, Young Chun [Korea Atomic Energy Res. Inst., Taejon (Korea, Republic of)

1993-12-01

305

Development of technical information processing systems  

International Nuclear Information System (INIS)

The major goal of this project is to develop a more efficient information management system by connecting the KAREI serials database which enable the users to access from their own laboratory facilities through KAREI-NET. The importance of this project is to make the serials information of KAERI easily accessible to users as valuable resources for R and D activities. The results of the project are as follows. 1) Development of the serials database and retrieval system enabled us to access to the serials holding information through KAERI-NET. 2) The database construction establishes a foundation for the management of 1,600 serials held in KAERI. 3) The system can be applied not only to KAERI but also to similar medium-level libraries. (Author)

306

Development of radiation detection and measurement systems  

Energy Technology Data Exchange (ETDEWEB)

This report contains descriptions on the following six items. The first item is the result of a study on CsI(TI) crystals with their light emitting characteristics and the result of a study on plastic scintillators. The second item is the result of a study on advanced radiation detectors and includes experiments for the effect of using a Compton suppressor with an HPGe detector. For the third item, we describe the results of a design work done using EGS4 for a thickness gauge, a density gauge, and a level gauge. The fourth item contains descriptions on the prototype circuit systems developed for a level gauge, a thickness gauge, and for a survey meter. The fifth part contains the computed tomography algorithm and a prototype scanning system developed for a CT system. As the sixth and the last item, we describe the prototype high precision heat source and the prototype heat-voltage converter which we have designed and fabricated.

Moon, B. S.; Ham, C. S.; Chung, C. E. and others

2000-03-01

307

Research and Development Management System (RDMS)  

International Nuclear Information System (INIS)

Research and Development (R and D) is a main activity carried out at the Malaysian Nuclear Agency particularly in the physical science and nuclear field. The R and D activity that is carried out needs to be managed more efficiently and systematically. Until now all research management activities are carried out manually or semi electronically, beginning from filling in application forms to when the project is completed. Therefore a computerized system is needed in order to manage and monitor R and D projects. The R and D system is capable of giving access information concerning R and D projects which are carried out to users inside and outside the agency. The R and D management system (RDMS) can increase the capability of the Malaysian Nuclear Agency in managing, researching and developing, innovating and inventing technology as well as commercializing the R and D produced. (author)

308

Controls system developments for the ERL facility  

Energy Technology Data Exchange (ETDEWEB)

The BNL Energy Recovery LINAC (ERL) is a high beam current, superconducting RF electron accelerator that is being commissioned to serve as a research and development prototype for a RHIC facility upgrade for electron-ion collision (eRHIC). Key components of the machine include a laser, photocathode, and 5-cell superconducting RF cavity operating at a frequency of 703 MHz. Starting with a foundation based on existing ADO software running on Linux servers and on the VME/VxWorks platforms developed for RHIC, we are developing a controls system that incorporates a wide range of hardware I/O interfaces that are needed for machine R&D. Details of the system layout, specifications, and user interfaces are provided.

Jamilkowski, J.; Altinbas, Z.; Gassner, D.; Hoff, L.; Kankiya, P.; Kayran, D.; Miller, T.; Olsen, R.; Sheehy, B.; Xu, W.

2011-10-07

309

Towards a Provotyping Approach in Systems Development  

DEFF Research Database (Denmark)

This paper explores the notion of ‘provocation through concrete experience’ towards a provotyping approach. It addresses the question: How do we on the one hand, devise qualitatively new systems, and on the other hand, ensure their usability in a given practice? The notion of provocation through concrete experience is developed through an investigation of prototyping and activity theory. Exploration of this notion leads to the idea of the systemdeveloper ‘provoking ’ concrete, everyday practice, by exposing current problems, calling forth what usually is taken for granted. Problems with current practice and a lack of mutual understanding, usually conceived of as hindrances to successful systems development, are used constructively. These ideas are compared to four related approaches: Future Workshops, Metaphorical Design, Cooperative Prototyping, and Organizational Games. The comparison serves the twofold purpose of contextualizing the new ideas as well as developing techniques for carrying themout.

Mogensen, Preben Holst

1992-01-01

310

Oral health care systems in developing and developed countries  

DEFF Research Database (Denmark)

Health care systems are essential for promoting, improving and maintaining health of the population. Through an efficient health service, patients can be advised of disease that may be present and so facilitate treatment; risks factors whose modification could reduce the incidence of disease and illness in the future can be identified, and further, how controlling such factors can contribute to maintain a good quality of life. In developed countries, clinics or hospitals may be supported by health professionals from various specialties that allow their cooperation to benefit the patient; these institutions or clinics may be equipped with the latest technical facilities. In developing countries, health services are mostly directed to provide emergency care only or interventions towards certain age group population. The most common diseases are dental caries and periodontal disease and frequently intervention procedures aim, at treating existing problems and restore teeth and related structure to normal function. It is unfortunate that the low priority given to oral health hinders acquisition of data and establishment of effective periodontal care programmes in developing countries but also in some developed countries where the periodontal profile is also less than satisfactory. Despite the fact that in several developed countries there are advanced programmes oriented to periodontal disease treatments, the concern is related to the lack of preventive oriented treatments. According to data available on periodontal status of populations from developed countries, despite the number of dentists and trained specialists, dental health professionals do not presently meet adequately the need for prevention, focusing mainly on curative care. The need for strengthening disease prevention and health promotion programmes in order to improve oral health conditions and particularly periodontal status in the majority of countries around the world is evident. Unfortunately, in many countries, the human, financial and material resources are still insufficient to meet the need for oral health care services and to provide universal access, especially in disadvantaged communities, in both developing and developed countries. Moreover, even though the most widespread illnesses are avoidable, not all population groups are well informed about or able to take advantage of the proper measures for oral health promotion. In addition, in many countries, oral health care needs to be fully integrated into national or community health programmes. Improving oral health is a very challenging objective in developing countries, but also in developed countries, especially with the accelerated aging of the population now underway and intensifying over the coming years.

Kandelman, Daniel; Arpin, Sophie

2012-01-01

311

Development of compact CCTV surveillance system. 'COSMOS'  

International Nuclear Information System (INIS)

The Compact Surveillance and Monitoring System, 'COSMOS' has been developed as a compact, simple, highly reliable CCTV surveillance system. The system is intended to provide a direct replacement for the IAEA Twin Minolta film camera systems. The system consists of a recording unit and a set up/review unit. The recording unit, consisting of a CCD camera module, a 8mm VTR unit, a controller module and a power unit, is contained in a tamper indicating housing. The VTR module of very low power consumption is specially developed for COSMOS capable of battery operation. The system can be operated for three months either by battery without battery change where mains power is not readily available or by AC powers. The field-use model of COSMOS was completed in 1991. The field-evaluation test by the IAEA and JAERI was successfully completed in 1993. The IAEA accepted the COSMOS as a routine-use device in August 1993. This report describes the performance features and IAEA test result of COSMOS. (author)

312

Development of Intellectual Reactor Design System: IRDS  

International Nuclear Information System (INIS)

In the frame of the new theme 'Study of analysis method of new nuclear power systems' admitted in our Reactor system laboratory since FY 1988, a program to develop the Intellectual Reactor Design System (IRDS) in the same spirit as ADES has been established. This report describes the activities related to IRDS performed in FY 1989. One of major activities is drafting IRDS. It reflects the conclusion of the STA ADES committee. The essence is to construct a modular system under the object-oriented programming environment to provide a conversational tool for feasibility study and conceptual design. Along the draft the following items were executed in the FY. For the realization of the conversational tool, a tool for input data generation by an object-oriented programming and another tool like CAD for geometry input data generation by a conversational processing of figures on display were examined. Upon the study how to construct the object-oriented data base, the class and frame structures of the design data base were drafted. As components of the modular system, programming of a neutronics and a thermohydraulics module for feasibility study was started. Also a structure analysis code was studied for conversion. In the coming FY, the computer system which has been composed by a FACOM host machine and terminals or isolated PCs will be exchanged by a SUN work-station linked with the host machine and PCs by an ETHER network. Under the suitable environment, the development of IRDS will be promoted. (author)

313

Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore.  

Science.gov (United States)

The spindle assembly checkpoint (SAC) is a quality control device to ensure accurate chromosome attachment to spindle microtubule for equal segregation of sister chromatid. Aurora B is essential for SAC function by sensing chromosome bi-orientation via spatial regulation of kinetochore substrates. However, it has remained elusive as to how Aurora B couples kinetochore-microtubule attachment to SAC signaling. Here, we show that Hec1 interacts with Mps1 and specifies its kinetochore localization via its calponin homology (CH) domain and N-terminal 80 amino acids. Interestingly, phosphorylation of the Hec1 by Aurora B weakens its interaction with microtubules but promotes Hec1 binding to Mps1. Significantly, the temporal regulation of Hec1 phosphorylation orchestrates kinetochore-microtubule attachment and Mps1 loading to the kinetochore. Persistent expression of phosphomimetic Hec1 mutant induces a hyperactivation of SAC, suggesting that phosphorylation-elicited Hec1 conformational change is used as a switch to orchestrate SAC activation to concurrent destabilization of aberrant kinetochore attachment. Taken together, these results define a novel role for Aurora B-Hec1-Mps1 signaling axis in governing accurate chromosome segregation in mitosis. PMID:24187132

Zhu, Tongge; Dou, Zhen; Qin, Bo; Jin, Changjiang; Wang, Xinghui; Xu, Leilei; Wang, Zhaoyang; Zhu, Lijuan; Liu, Fusheng; Gao, Xinjiao; Ke, Yuwen; Wang, Zhiyong; Aikhionbare, Felix; Fu, Chuanhai; Ding, Xia; Yao, Xuebiao

2013-12-13

314

EXPERT SYSTEMS - DEVELOPMENT OF AGRICULTURAL INSURANCE TOOL  

Directory of Open Access Journals (Sweden)

Full Text Available Because of the fact that specialty agricultural assistance is not always available when the farmers need it, we identified expert systems as a strong instrument with an extended potential in agriculture. This started to grow in scale recently, including all socially-economic activity fields, having the role of collecting data regarding different aspects from human experts with the purpose of assisting the user in the necessary steps for solving problems, at the performance level of the expert, making his acquired knowledge and experience available. We opted for a general presentation of the expert systems as well as their necessity, because, the solution to develop the agricultural system can come from artificial intelligence by implementing the expert systems in the field of agricultural insurance, promoting existing insurance products, farmers finding options in depending on their necessities and possibilities. The objective of this article consists of collecting data about different aspects about specific areas of interest of agricultural insurance, preparing the database, a conceptual presentation of a pilot version which will become constantly richer depending on the answers received from agricultural producers, with the clearest exposure of knowledgebase possible. We can justify picking this theme with the fact that even while agricultural insurance plays a very important role in agricultural development, the registered result got from them are modest, reason why solutions need to be found in the scope of developing the agricultural sector. The importance of this consists in the proposal of an immediate viable solution to correspond with the current necessities of agricultural producers and in the proposal of an innovative solution, namely the implementation of expert system in agricultural insurance as a way of promoting insurance products. Our research, even though it treats the subject at an conceptual level, it wants to undertake an attempt to present the necessity and importance of implementing expert systems in agricultural insurance as a solution of development of the Romanian agricultural sector since insurance play an important role in the stimulation of investments in agriculture and in the stabilization of agricultural producers incomes. The results of the study, at a conceptual level, confirms the necessity of aplying expert systems in agricultural insurance because of the benefits which would be created (informing agricultural producers about the existence and importance of agricultural insurance, the development of the insurance market which would lead to the development of agriculture, creation of new insurance products adapted to the needs of the farmers.

NAN Anca-Petru?a

2013-07-01

315

Information system development activities and inquiring systems : an integrating framework  

DEFF Research Database (Denmark)

This article presents a framework that maps information system development (ISD) activities on systems for the creation of knowledge. This work addresses the relevant and persisting problem of improving the chances of ISD success. The article builds upon previous research on knowledge aspects of ISD, abandoning the idea of a monolithic approach to knowledge and presenting a pluralistic approach based on the idea that different inquiring systems can support micro-level ISD activities. The article is divided into two parts. The first part presents the theoretical development of the framework based on ISD literature and on Churchman's (1971) inquiring systems. The second part presents the use of the framework in an ISD project. The case is used to show the applicability of the framework and to highlight the advantages of this approach. The main theoretical implication is that the framework provides a new way to see the development of a system in terms of the knowledge created in the process. The main practical implication of the framework is that it improves the managers' ability to guide ISD activities as knowledge activities embedded in a knowledge process, a crucial element in development projects. Udgivelsesdato: APR

Carugati, Andrea

2008-01-01

316

Advanced Turbine Systems Program industrial system concept development  

Energy Technology Data Exchange (ETDEWEB)

The objective of Phase II of the Advanced Turbine Systems Program is to develop conceptual designs of gas fired advanced turbine systems that can be adapted for operation on coal and biomass fuels. The technical, economic, and environmental performance operating on natural gas and in a coal fueled mode is to be assessed. Detailed designs and test work relating to critical components are to be completed and a market study is to be conducted.

Gates, S. [Solar Turbines Inc., San Diego, CA (United States)

1995-10-01

317

Development of fully automatic pipe welding system  

International Nuclear Information System (INIS)

We have succeeded in developing a fully automatic TIG welding system; namely CAPTIG that enables unmanned welding operations from the initial layer to the final finishing layer continuously. This welding system is designed for continuous, multilayered welding of thick and large diameter fixed pipes of nuclear power plants and large-size boiler plants where high-quality welding is demanded. In the tests conducted with this welding system, several hours of continuous unmanned welding corroborated that excellent beads are formed, good results are obtained in radiographic inspection and that quality welding is possible most reliably. This system incorporates a microcomputer for fully automatic controls by which it features a seam tracking function, wire feed position automatic control function, a self-checking function for inter-pass temperature, cooling water temperature and wire reserve. (author)

318

Airborne water vapor DIAL system development  

Science.gov (United States)

A differential absorption lidar (DIAL) system developed at NASA Langley Research Center for the remote measurement of atmospheric H2O and aerosols from an aircraft is briefly discussed. This DIAL system utilizes a Nd:YAG laser-pumped dye laser as the off-line transmitter and a narrowband, tunable Alexandrite laser as the on-line transmitter. A 1-m monochromator and a multipass absorption cell are used to position the on-line laser to the center of the H2O line. The receiver system has a 14-in. diameter, f/7 Celestron telescope to collect the backscattered laser light and focus in into the detector optics. Return signals are converted to electrical signals by the optical detector and are digitalized and stored on magnetic tape. The results of fligh tests of the system are shown.

Higdon, Noah S.; Browell, Edward V.; Ponsardin, Patrick; Grossmann, Benoist E.

1990-01-01

319

Developing 360 degree feedback system for KINS  

Energy Technology Data Exchange (ETDEWEB)

This project aims to investigate the feasibility of a 360 degree feedback systems for KINS and to design guiding rules and structures in implementing that systems. Literature survey, environmental analysis and questionnaire survey were made to ensure that 360 degree feedback is the right tool to improve performance in KINS. That review leads to conclusion that more readiness and careful feasibility review are needed before implementation of 360 degree feedback in KINS. Further the project suggests some guiding rules that can be helpful for successful implementation of that system in KINS. Those include : start with development, experiment with one department, tie it to a clear organization's goal, train everyone involve, make sure to try that system in an atmosphere of trust.

Han, In Soo; Cheon, B. M.; Kim, T. H.; Ryu, J. H. [Chungman National Univ., Daejeon (Korea, Republic of)

2003-12-15

320

Developing 360 degree feedback system for KINS  

International Nuclear Information System (INIS)

This project aims to investigate the feasibility of a 360 degree feedback systems for KINS and to design guiding rules and structures in implementing that systems. Literature survey, environmental analysis and questionnaire survey were made to ensure that 360 degree feedback is the right tool to improve performance in KINS. That review leads to conclusion that more readiness and careful feasibility review are needed before implementation of 360 degree feedback in KINS. Further the project suggests some guiding rules that can be helpful for successful implementation of that system in KINS. Those include : start with development, experiment with one department, tie it to a clear organization's goal, train everyone involve, make sure to try that system in an atmosphere of trust

 
 
 
 
321

Development of the real time monitor system  

International Nuclear Information System (INIS)

Large-scale simulation technique is studied at the Center for Promotion of Computational Science and Engineering (CCSE) for the computational science research in nuclear fields. Visualization and animation processing technique are studied and developed for efficient understanding of simulation results. The real time monitor system, in which on-going simulation results are transferred from a supercomputer or workstation to a graphic workstation and are visualized and recorded, is described in this report. This system is composed of the graphic workstation and the video equipment connected to the network. The control shell programs are the job-execution shell for simulations on supercomputers, the file-transfer shell for output files for visualization, and the shell for starting visualization tools. Special image processing technique and hardware are not necessary in this system and the standard visualization tool AVS and the UNIX commands are used, so that this system can be implemented and applied in various computer environments. (author)

322

Development of the Darlington dousing system  

International Nuclear Information System (INIS)

Consolidation of component development programs design optimization strategy and testing experience has resulted in a compact, efficient design for the Darlington Dousing System. As an integral part of the Negative Pressure Containment Concept employed in CANDU multi-unit stations, the role of the Dousing System is to rapidly cool and condense steam drawn into the Vacuum Structure in the event of a Loss of Coolant Accident. Given a Vacuum Structure larger than at other stations, a maximum flowrate target was established to meet safety requirements. The riser pipes and spray plates are sized to meet the peak flow requirement while conserving water for small breaks and maximizing the head available on the spray plates. To improve the thermal utilization of the spray a development program was undertaken which resulted in the design of a novel domed spray plate which exhibited good spray characteristics over a wide range of driving pressures. Loss coefficients for the dousing system were determined in a 1/16 scale model. A computer model of the spray header was developed to optimize spray plate layout for uniform water distribution. Commissioning tests at Pickering and Bruce stations aided in the design and revealed unique dousing characteristics. This includes air entrainment which lowers upper chamber pressure and can lead to over-dousing. System performance is analyzed by a thermal-hydraulic to the rest of containment by the energy removal rate in the Vacuum Structure

323

MIT: Global System for Sustainable Development  

Science.gov (United States)

Global System for Sustainable Development (GSSD) is a project of the Global Accords Consortium for Sustainable Development that is "dedicated to internationalization of knowledge access, provision & sharing for 'reducing the gap between knowledge & policy.'" Housed at the Massachusetts Institute of Technology (MIT), GSSD is "a multi-dimensional knowledge networking system" that combines public and private networks to provide a continually evolving cross-referenced knowledge base for informing decision-making and policy in the domain of "sustainable development." The Using GSSD section of the website provides information on the organizing principles used to develop the database, demonstrates the functionality and architecture of the system and other aspects of the project, such as the multiple mirror sites that are in languages other than English. Reports and working papers from the GSSD are also posted. Visitors can search the holdings of the database using a text search or based on other parameters, such as issue area or industry type, and are invited to submit websites to be considered for inclusion.

324

Development of the Medium Energy Linac Systems  

International Nuclear Information System (INIS)

The main purpose of this project is developing 100-MeV proton linear accelerator (linac) for proton engineering frontier project (PEFP). In the first phase of the PEFP, the development of the 20-MeV linac has successfully finished. Hence the work scope of this project is designing the linac to accelerate proton beams from 20-MeV up to 100-MeV, fabricating the linac up to 45 MeV, fabricating one set of the medium energy beam transport (MEBT) tank, and developing the low level radio frequency (LLRF) system and the control system. The basic role of the new proton accelerator is accelerating 20-mA proton beams from 20 MeV up to 100 MeV. The first step of the design procedure is optimizing and determining the accelerator parameters. The beam loss is also main concern in the design stage. The drift tube (DT) and the quadrupole magnets are designed to be optimized to the new linac design. The other purpose is confirming the new design by fabricating and tuning the drift tube linac (DTL). The 20MeV proton beam divided into two directions. One is supplying the beams to user group by turning on the 45-degree bending magnet. The other is guided into the 100-MeV DTL by tuning off the dipole magnet. That is why the PEFP MEBT located after 20-MeV DTL. The MEBT is realized as two small DTL tanks with three cells and a 45-degree bending magnet. The fabrication of one MEBT tank is another purpose of this project. The other purposes of this project is developing the LLRF system to control the RF signal and control system to monitor and control the vacuum system, magnet power supply, etc

325

Sensor Development for PEM Fuel Cell Systems  

Energy Technology Data Exchange (ETDEWEB)

This document reports on the work done by Honeywell Sensing and Control to investigate the feasibility of modifying low cost Commercial Sensors for use inside a PEM Fuel Cell environment. Both stationary and automotive systems were considered. The target environment is hotter (100 C) than the typical commercial sensor maximum of 70 C. It is also far more humid (100% RH condensing) than the more typical 95% RH non-condensing at 40 C (4% RH maximum at 100 C). The work focused on four types of sensors, Temperature, Pressure, Air Flow and Relative Humidity. Initial design goals were established using a market research technique called Market Driven Product Definition (MDPD). A series of interviews were conducted with various users and system designers in their facilities. The interviewing team was trained in data taking and analysis per the MDPD process. The final result was a prioritized and weighted list of both requirements and desires for each sensor. Work proceeded on concept development for the 4 types of sensors. At the same time, users were developing the actual fuel cell systems and gaining knowledge and experience in the use of sensors and controls systems. This resulted in changes to requirements and desires that were not anticipated during the MDPD process. The concepts developed met all the predicted requirements. At the completion of concept development for the Pressure Sensor, it was determined that the Fuel Cell developers were happy with off-the-shelf automotive pressure sensors. Thus, there was no incentive to bring a new Fuel Cell Specific Pressure Sensor into production. Work was therefore suspended. After the experience with the Pressure Sensor, the requirements for a Temperature Sensor were reviewed and a similar situation applied. Commercially available temperature sensors were adequate and cost effective and so the program was not continued from the Concept into the Design Phase.

Steve Magee; Richard Gehman

2005-07-12

326

Development of FBR cycle data base system  

International Nuclear Information System (INIS)

In the 'Feasibility Study on Commercialized Fast Reactor Cycle System (F/S)'. scenario evaluations, cost-benefit evaluations and system characteristic evaluations to show significance of the Fast Breeder Reactor (FBR) cycle system introduction concretely are performed in parallel with a design study for FBR plants, reprocessing systems and fabrication systems. In these evaluations, informations such as economic prospects, prospects for supply and demand of resources and a progress of engineering development are used in addition to design information. This report explains a FBR Cycle Database in order to carry out management and search of various design information and the relating information. The prototype system of the database was completed in the 2000 fiscal year, and the problem of the user number restriction of the prototype system has been improved by Web-ization in the 2001 fiscal year. About 7,000 data are stored in this data base (as of the end of March, 2002). The expansion of user etc., and the continuation of input work of various evaluation information will be carried out, in the phase 2 of F/S. (author)

327

Development of evaluation system for flashing erosion  

International Nuclear Information System (INIS)

Liquid droplet impingement erosion (LDI) is defined as an erosion phenomenon caused by high-speed droplet attack in a wet steam flow, and sometimes observed in a steam piping system of a power plant. In our previous researches, we have developed an LDI evaluation system to evaluate the thinning shape due to LDI on a steam piping within a practically acceptable time. However, present system is not applicable to LDI on a hot-water piping due to flashing phenomena (flashing erosion) because it is difficult to calculate the flashing flow due to sudden phase change and critical flow rate evaluation models needed for LDI evaluation system are not verified in wet steam region. Therefore, in this study, we tried to develop a new flow calculation code for flashing flow and to verify the critical flow rate evaluation models in wet steam region. For flashing flow simulation, based on a present CFD code, pre-conditioning method was adopted to achieve the stable calculation of the water region, and extended look-up table including from low-pressure water to high-pressure dry steam was incorporated. Finally, a new CFD code water-steam flow was developed. Several benchmark tests were conducted and those results show this new code can reproduce the flashing phenomena and is applicable from the very low-speed flow to supersonic flow. Then, HEM model for critical mass flow rate was verified with flashing and wet steam experiments and CFD calculations, and incorporated into LDI evaluation system to extend applicable region of the evaluation system into flashing erosion. (author)

328

Equipment system for advanced nuclear fuel development  

International Nuclear Information System (INIS)

The purpose of the settlement of equipment system for nuclear Fuel Technology Development Facility(FTDF) is to build a seismic designed facility that can accommodate handling of nuclear materials including <20% enriched Uranium and produce HANARO fuel commercially, and also to establish the advanced common research equipment essential for the research on advanced fuel development. For this purpose, this research works were performed for the settlement of radiation protection system and facility special equipment for the FTDF, and the advanced common research equipment for the fuel fabrication and research. As a result, 11 kinds of radiation protection systems such as criticality detection and alarm system, 5 kinds of facility special equipment such as environmental pollution protection system and 5 kinds of common research equipment such as electron-beam welding machine were established. By the settlement of exclusive domestic facility for the research of advanced fuel, the fabrication and supply of HANARO fuel is possible and also can export KAERI-invented centrifugal dispersion fuel materials and its technology to the nations having research reactors in operation. For the future, the utilization of the facility will be expanded to universities, industries and other research institutes

329

Development of design window evaluation and display system. 1. System development and performance confirmation  

International Nuclear Information System (INIS)

Purpose: The work was performed to develop a design window evaluation and display system for the purpose of obtaining the effects of various design parameters on the typical thermal hydraulic issues resulting from a use of various kind of working fluid etc. easily. Method: The function of the system were 'confirmation of design margin' of the present design, 'confirmation of the affected design zone' when a designer changed some design parameter, and search for an design improvement' for design optimization. The system was developed using existing soft wares on PC and the database relating analytical results of typical thermal hydraulic issues provided by separate work. Results: (1) System design: In order to develop a design window evaluation and display system, 'numerical analysis unit', 'statistical analysis unit', 'MMI unit', 'optimization unit' were designed based on the result of selected optimization procedure and display visualization. Further, total system design was performed combining these units. Typical thermal hydraulic issues to be considered are upper plenum thermal hydraulics, thermal stratification, free surface sloshing, flow-induced vibration of a heat exchanger and thermal striping in the T-junction piping systems. (2) Development of prototype system and a functional check: A prototype system of a design window evaluation and display system was developed and the functions were confirmed as was planned. (author)thor)

330

Risk management in information system development  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The purpose of this study is to facilitate the implementation process of the case corporation’s new information system for managing their inventory of bus tires. This study attempts to answer the questions “What were the main IT-risks in-volved with the development and implementation of the new bus tire inventory management system, what kind of effects did they have and how were they dealt with”. The study was carried out with the cooperation of the case corporation, Koiviston Auto, as ...

Ristola, Teemu

2011-01-01

331

Reframing Humans in Information Systems Development  

CERN Document Server

Modern society has been transformed by the digital convergence towards a future where technologies embed themselves into the fabric of everyday life. This ongoing merging of social and technological infrastructures provides and necessitates new possibilities to renovate past notions, models and methods of information systems development that accommodates humans as actors within the infrastructure. This shift introduces new possibilities for information systems designers to fulfil more and more everyday functions, and to enhance their value and worth to the user. "Reframing Humans in Infor

Isomaki, Hannakaisa

2011-01-01

332

Developments in electronic portal imaging systems.  

Science.gov (United States)

Verification of geometric accuracy at the time of treatment delivery has always been a necessary part of the radiotherapy process. Since the introduction of conformal and intensity-modulated radiotherapy, the consequences of patient positioning errors are more serious. Portal imaging has played a large part in fulfilling the need for improved geometric accuracy. This review examines how portal imaging has progressed through the development and evolution of electronic portal imaging devices (EPIDs). Changes in technology, including the current commercial systems, and how image quality has changed are presented. The clinical usage of EPIDs and the technological innovations being devised for further improvements in image quality and systems are considered. PMID:16980685

Kirby, M C; Glendinning, A G

2006-09-01

333

Development of A Plant Navigation System  

International Nuclear Information System (INIS)

A 'Plant Navigation System (PNS)' is under development to assist nuclear power plant (NPP) operators by automatically displaying the plant situation and plant operational procedures on a CRT screen when abnormalities occur. The operation procedures given in a symptom-oriented manual are expressed in a tree - type flowchart (modified PAD). The optimum operation procedure for an NPP is selected automatically using built-in diagnostic logics based on the current status of the NPP. Concerning the plant situation, the PNS displays important information only on the current status of the NPP. A prototype PNS system is being constructed. (authors)

334

Development of in-situ monitoring system  

Energy Technology Data Exchange (ETDEWEB)

Development of in-situ monitoring system using an optical fiber to measure the real time temperature variation of subsurface water for the evaluation of flow characteristics. We describe the feasibility of developing a fiber-optic temperature sensor using a thermochromic material. A sensor-tip is fabricated by mixing of a thermochromic material powder. The relationships between the temperatures and the output voltages of detectors are determined to measure the temperature of water. It is expected that the fiber-optic temperature monitoring sensor using thermochromic material can be used to measure the real time temperature variation of subsurface water

Lee, Bong Soo; Cho, Dong Hyun; Yoo, Wook Jae; Heo, Ji Yeon [Konkuk University, Seoul (Korea, Republic of)

2010-03-15

335

Development of Portable Multicoincidence Radionuclide Analysis Systems  

Energy Technology Data Exchange (ETDEWEB)

Multicoincidence radionuclide analysis systems consisting of light-charged-particle detectors operating in coincidence with photon spectrometers are being developed to improve the sensitivity of radionuclide analysis in field applications. Requiring charged-particle/photon coincidence provides active shielding from environmental photon sources, and mapping photon-photon events into a coincidence plane can remove photon spectroscopy interferences. List-mode data acquisition and flexible hardware design ensures that the most sensitive coincidence schemes involving beta, atomic electron, gamma and x-ray emissions can be used for radionuclide quantification. System hardware design and preliminary measurement data are discussed. A centerpiece component of this project, the development of analysis tools and data libraries required to perform automated multicoincidence analysis, is also described.

Smith, Eric E.(BATTELLE (PACIFIC NW LAB)); Aalseth, Craig E.(BATTELLE (PACIFIC NW LAB)); Hossbach, Todd W.(BATTELLE (PACIFIC NW LAB)); Miley, Harry S.(BATTELLE (PACIFIC NW LAB)); Perkins, Richard W.(BATTELLE (PACIFIC NW LAB)); Ellis, Edward E.(BATTELLE (PACIFIC NW LAB))

2003-06-01

336

Stirling Convertor System Dynamic Model Developed  

Science.gov (United States)

Free-piston Stirling convertors are being developed for potential use on NASA exploration missions. In support of this effort, the NASA Glenn Research Center has developed the Stirling convertor System Dynamic Model (SDM). The SDM models the Stirling cycle thermodynamics; heat flow; gas, mechanical, and mounting dynamics; the linear alternator; and the controller. The SDM s scope extends from the thermal energy input to thermal, mechanical, and electrical energy output, allowing one to study complex system interactions among subsystems. Thermal, mechanical, fluid, magnetic, and electrical subsystems can be studied in one model. The SDM is a nonlinear time-domain model containing sub-cycle dynamics, which simulates transient and dynamic phenomena that other models cannot. The entire range of convertor operation is modeled, from startup to full-power conditions.

Lewandowski, Edward J.; Regan, Timothy F.

2005-01-01

337

Legacy Information System Development: Problems and Issues  

Directory of Open Access Journals (Sweden)

Full Text Available The Information Communication Technology has improved the quality of services being provided by organizations beyond proportions. Another most distinguishing characteristic of ICT is the storage, retrieval, processing as well as the communication of Data. However development of Information System is always associated with many problems and issues. In fact resistance to change is a universally acknowledged fact but since the influence of ICT is felt at all levels therefore automation mostly meets multifold problems. It is because of this fact that despite distinct superiority of ICT still it is implemented in phased manner. Similarly the available technology also limits the working of the Information System. Other issues related with the development of the information are the developmental, operational besides security.

Muheet Ahmed Butt

2012-12-01

338

A Guerilla Approach to Control System Development  

CERN Document Server

We present our experiences in managing the development cycles of the control systems for ANKA and the ALMA Common Software. Our team consists practically only of undergraduate students. Stimulating and rewarding the students with cutting-edge technologies and travel to conferences like this and installation fieldwork are an important positive factor in raising their motivation. However, building any system with a group of inexperienced students is quite a challenging task. Many problems occur with planning deadlines and missing them, organizing and managing development, sources, and documentation and also when dealing with conventional program management rules. To cope with them, we use many tools: CVS for versioning and source archiving, Bugzilla for keeping our bugs in order, a to-do list for managing tasks, an activity log and also many other programs and scripts, some found on the Internet and some made by ourselves. In the end, we had to become organized like a professional company. Documentation and dem...

Dovc, J; Plesko, M

2001-01-01

339

Development of portable multicoincidence radionuclide analysis systems  

International Nuclear Information System (INIS)

Multicoincidence radionuclide analysis systems consisting of light-charged-particle detectors operating in coincidence with photon spectrometers are being developed to improve the sensitivity of radionuclide analysis in field applications. Requiring charged-particle/photon coincidence provides active shielding from environmental photon sources, and mapping photon-photon events into a coincidence plane can remove photon spectroscopy interferences. List-mode data acquisition and flexible hardware design ensures that the most sensitive coincidence schemes involving ?, atomic electron, ? and X-ray emissions can be used for radionuclide quantification. System hardware design and preliminary measurement data are discussed. A centerpiece component of this project, the development of analysis tools and data libraries required to perform automated multicoincidence analysis, is also described

340

Laser-produced plasma source system development  

Science.gov (United States)

This paper provides a review of development progress for a laser-produced-plasma (LPP) extreme-ultra-violet (EUV) source with performance goals targeted to meet joint requirements from all leading scanner manufacturers. Laser produced plasma systems have been developed as a viable approach for the EUV scanner light source for optical imaging of circuit features at sub-32nm and beyond nodes on the ITRS roadmap. Recent advances in the development of the system, its present average output power level and progress with various subcomponents is discussed. We present the latest results on peak EUV and average EUV power as well as stability of EUV output, measured in burst-mode operation at the nominal repetition rate of the light source. In addition, our progress in developing of critical components, such as normal-incidence EUV collector and liquid-target delivery system is described. We also report on dose stability, plasma position stability and EUV distribution at the output region of the source. This presentation reviews the experimental results obtained on systems with a focus on the topics most critical for an HVM source. The capability to scale LPP power by further development of the high power CO2 drive laser in order to increase duty cycle and duration of continuous light source operation is shown. Production systems with thermal management and capable of 5 sr light collection are being assembled and tested. A description of the development of a normal-incidence ellipsoidal collector is included. Improvements in substrate quality lead to increased EUV reflectance of the mirror. Results on the generation of liquid tin droplets as target material for efficient plasma generation are also described. The droplet generator serves as a key element in the precise and spatially stable delivery of small quantities of liquid tin at high repetition rates. We describe a protection module at the intermediate focus (IF) region of the source and imaging of the EUV distribution using a sub-aperture collector and a fluorescent screen. A path to meet requirements for production scanners planned well into the next decade is also presented.

Brandt, David C.; Fomenkov, Igor V.; Ershov, Alex I.; Partlo, William N.; Myers, David W.; Böwering, Norbert R.; Vaschenko, Georgiy O.; Khodykin, Oleh V.; Bykanov, Alexander N.; Hoffman, Jerzy R.; Chrobak, Christopher P.; Srivastava, Shailendra N.; Vidusek, David A.; De Dea, Silvia; Hou, Richard R.

2008-11-01

 
 
 
 
341

Development of a laundry radwaste treatment system  

International Nuclear Information System (INIS)

Fundamental bench tests have been performed to develop a radioactive laundry radwaste treatment system, involving ozone/activated carbon, reverse osmosis membrane, and ion exchanger. A pre-treatment technique was employed for the removal of detergent, using a ozonization (ozone/H2O2). Adsorption of detergent and radionuclides by various commercial adsorbents and removal of radionuclides by reverse osmosis membrane have been investigated. The removal rates of radionuclides and/or detergents are presented for each process. (author)

342

Development of cask and transportation system  

International Nuclear Information System (INIS)

Transportation of spent fuels to the AFR interim storage facility and disposal repository are necessary in Korea. Therefore, an emphasis has been concentrated to develop the design and fabrication technology of commercial casks. A conceptual design of the temperature and deformation measuring systems in the cask, which will be used for mock-up tests has been performed. Preliminary design data of the cask for 7 spent PWR fuels have been obtained in the course of study. (author)

343

Low cost attitude control system scanwheel development  

Science.gov (United States)

In order to satisfy a growing demand for low cost attitude control systems for small spacecraft, development of low cost scanning horizon sensor coupled to a low cost/low power consumption Reaction Wheel Assembly was initiated. This report addresses the details of the versatile design resulting from this effort. Tradeoff analyses for each of the major components are included, as well as test data from an engineering prototype of the hardware.

Bialke, William; Selby, Vaughn

1991-01-01

344

Development of integrated analytical data management system  

International Nuclear Information System (INIS)

The Analysis Subsection of Technical Service Section, Tokai Reprocessing Plant, Tokai Works, is engaged in analysis activities required for the management of processes and measurements in the plant. Currently, it has been desired to increase the reliability of analytical data and to perform analyses more rapidly to cope with the increasing number of analysis works. To meet this end, on-line data processing has been promoted and advanced analytical equipment has been introduced in order to enhance automization. In the present study, an integrated analytical data mangement system is developed which serves for improvement of reliability of analytical data as well as for rapid retrieval and automatic compilation of these data. Fabrication of a basic model of the system has been nearly completed and test operation has already been started. In selecting hardware to be used, examinations were made on easiness of system extension, Japanese language processing function for improving man-machine interface, large-capacity auxiliary memory system, and data base processing function. The existing analysis works wer reviewed in establishing the basic design of the system. According to this basic design, the system can perform such works as analysis of application slips received from clients as well as recording, sending, filing and retrieval of analysis results. (Nogami, K.)

345

Herding agent field application system development  

Energy Technology Data Exchange (ETDEWEB)

Chemical herding agents can be applied to deal with an oil slick. This study investigates the key system components of application systems for herding agents and shows how application systems can also be developed for operational herder usage in drift ice. These two application systems are respectively required for small boat and a helicopter operations. The factors, including the selection of flow rates, pressures and atomizing nozzle types, which give the appropriate herder droplet size distributions for small boat and aerial application systems were investigated in the initial stage of the study. In a later stage, on commercializing herders for in situ burning, further research is expected to deal with the many problems not tackled in the initial stage, such as the mounting of the nozzles, pumps and reservoirs on various aerial platforms and the provision of heating and insulation for cold-weather use. The paper presented the experiments and simulations that have been conducted as well as the basic design parameters for field application systems.

Buist, Ian; Belore, Randy [SL Ross Environmental Research (Canada)], email: ian@slross.com

2011-07-01

346

Development of 100Ci tritium handling system  

International Nuclear Information System (INIS)

A new experimental system has been developed for use of pure tritium amounting to 100 Ci at a time. The system consists of two experimental chambers and other components such as tritium storage-supply, gas purification, isotope separation, and exhaust gas handling devices. These components provide a complete tritium circulation in the system, and hence tritium waste can be minimized for a variety of experimental works. One of the chambers is designed for experiments using molecular tritium, and the other hand tritium plasma generated with ECR discharge. A Zr-Ni alloy is applied for impurity removal from the exhaust gas from both of the experimental chambers and gas chromatography is used for the isotope separation of purified hydrogen isotope mixtures. Other kinds of gettering materials are used for tritium isotope-supply. The exhaust gas handling system has two different devices; one is a conventional wet device, consisting of a Pt-catalyst bed and a molecular sieve bed, the other a dry device using two getter beds. This paper describes the details of the system as well as its components and the results of system performance test using non-radioactive hydrogen isotopes. (author)

347

Sustainable development of the Belgrade energy system  

Energy Technology Data Exchange (ETDEWEB)

Cities are the most important energy consumers of any country in all energy vector components. Nowadays, Belgrade as a cultural, educational, scientific, administrative, political, and business center of the region with its own structure of production, transportation, services, and urban system, represents significant consumer of different energy forms. Only useful and final energy is delivered to energy consuming sectors of a city. Simulation model MAED was used in this paper to estimate energy demand in city for a long time period. On the basis of energy demand forecast for three major 'energy consumers' (sectors of household/service, industry, and transportation) until 2020, the sustainable development 'scenarios' of Belgrade energy system are developed (2005-2010, 2010-2015, 2015-2020). For each 'scenario', the energy systems of primary resources are determined so to satisfy the predicted differences in energy consumption for the mentioned time intervals until 2020. In this case different 'scenarios' are evaluated. The evaluation of 'scenarios' sustainability is obtained by method of multi-criteria analysis. Using energy indices for sustainable development, the following indices are taken into consideration for the assessment of scenario sustainability: economical, social, and environmental. The obtained results can be used by experts in decision-making process. (author)

Jovanovic, Marina; Radovanovic, Predrag [Laboratory for Thermal Engineering and Energy, VINCA Institute of Nuclear Sciences, 11001 Belgrade (RS); Afgan, Naim [Mechanical Engineering Department, Insituto Superior Tecnico, 35121 Lisbon (Portugal); Stevanovic, Vladimir [Faculty of Mechanical Engineering, Belgrade University, 11000 Belgrade (RS)

2009-05-15

348

Development of remote visual inspection system  

International Nuclear Information System (INIS)

Visual inspection is one of the preliminary steps in qualification of any component. Also during the lifetime of the component, it has to see varying operating conditions. During this period the surface conditions of the component changes. Visual inspection is a useful tool for generating data of the surface conditions during pre service and in service inspection. This data is then useful in determining the extent of degradation during the service or to qualify the component for future service. The visual inspection gives the information about integrity of the component and thus aids in decision making whether repair or maintenance or some other inspection has to be carried out. This paper mainly highlights development of an inspection system to be used during steam generator lancing-Remote Visual Inspection System (RVIS). The RVIS is used to determine the steam generator tube sheet condition before and after lancing. The development of system was a challenge, considering dimensional restrains and small gap between the tubes through which tube sheet has to be seen. The RVIS was developed, fabricated, assembled and qualified on the steam generator mock up. The paper also briefs about various visual inspections carried out in the existing facilities in BARC for qualification, fault detection or reference data generation. All the visual inspections have been carried out after their qualification through mock up trials. In the end, current R and D work for characterization of images is also discussed. (author)

349

Resonant Kicker System Development at SLAC  

International Nuclear Information System (INIS)

The design and installation of the Linear Coherent Light Source [1] at SLAC National Accelerator Laboratory has included the development of a kicker system for selective beam bunch dumping. The kicker is based on an LC resonant topology formed by the 50 uF energy storage capacitor and the 64 uH air core magnet load which has a sinusoidal pulse period of 400us. The maximum magnet current is 500 A. The circuit is weakly damped, allowing most of the magnet energy to be recovered in the energy storage capacitor. The kicker runs at a repetition rate of 120Hz. A PLC-based control system provides remote control and monitoring of the kicker via EPICS protocol. Fast timing and interlock signals are converted by discrete peak-detect and sample-hold circuits into DC signals that can be processed by the PLC. The design and experimental characterization of the system are presented

350

Development of a fast closing valve system  

International Nuclear Information System (INIS)

A fast closing valve is connected to a beam line branched from an electron storage ring. It protects the ultra-high-vacuum (UHV) system against inrushes of air, which may accidentally occur at a measuring station located at the down stream of the beam flow. Tow types of fast closing valve systems have been developed. The closing time guaranteed is 50 ms and 10 sm respectively for the nearly same aperture size of 150 x 15 mm. The 10 ms FCV system is described. The leak rate characteristics are kept within about 0.1 Torr.lit/sec. (1.33 x 10-2 Pa m3/sec.), even after closing operations of 1000 times. (author)

351

Development of an intellectual maintenance management system. Development of trouble detection and troubleshooting evaluation system  

International Nuclear Information System (INIS)

Many research activities are conducted to enhance cost performance and safety of nuclear power plants operation and maintenance. Concept of autonomous operating system to equal the role of operators and of maintenance personnel with artificial intelligence and autonomous robots has been developed. An intellectual maintenance management system has been developed to be equipped with decision making functions of maintenance personnel. The intellectual maintenance management system is in charge of maintenance function of an autonomous plant, which consists of plant-wide monitoring, evaluation of component integrity, and scheduling of maintenance activities. In other words, this system should be equipped with preventive maintenance and corrective maintenance functions those are currently loaded on personnel. In this report, we discussed condition monitoring maintenance in the preventive maintenance. We also reported a sensor validation system development for machinery condition monitoring and diagnosis. We adopted distributed and cooperative system construction technique, which is expected recently in applications to large-scale plants. This system has inter-agent communication function for signal transmission and reception among distributed physics models of machineries. The system has been constructed for water/steam system of the LMFBR power plant. The system has been validated to be capable of cooperative sensor validation by the distributed set of agents, with quantitative indication of sensor deviation based on a newly developed fuzzy algorithm with inter-agent cooperation. The derived reference parameter value from the inter-agent evaluations also stands for the alternative measurement to the malfunctioned sensor. (author)

352

Development of the Medium Energy Linac Systems  

International Nuclear Information System (INIS)

The main purposes of the proton engineering frontier project is developing a proton linac which accelerates 20 mA proton beams up to 100 MeV and supplying 20 MeV and 100 MeV proton beams to the user groups. The project 'Development of the medium energy linac systems' is aiming to design the 100 MeV proton linac, to construct an accelerating cavity, to design a MEBT system, and to develop a energy measurement system. The 100 MeV linac consists of 20 DTL tanks which are operated by five additional klystrons. The focusing lattice is FFDD as the 20 MeV DTL. However the hollow conductors are used for coils of the quadrupole magnets. The shape of the drift tubes in the new tanks is changed to compensate the reduction of the accelerating efficiency in the high energy region. For example, the face angle of drift tubes begins at 40 degrees. The bore radius is selected as 10 mm in order to eliminate beam loss in the beam line. We can obtain the 100 MeV proton beams by using these accelerating structure. We have designed some of the tanks in detail. It covers the modification of the structure by including the stem, post-coupler, and sulg-tuner effects, the error analysis, the thermal and structure analysis, the drift tube design, the magnet design, the various ports design, the support structure design, the end-plate design, etc. Now the first DTL tank is constructed by a local company. An beam extraction system is essential after 20 MeV DTL in order to supply 20 MeV proton beams. Since there are no focusing elements in the structure, the beam should be spread out. The MEBT which consists of two 3-cell DTL tanks is designed to control the beam size in the beam extraction system by magnets in the first tank and to transversely match the beam into the next DTL by magnets in the the second tank. The longitudinal matching is done by the RF in both tanks. We have also developed an energy measurement system using the time of flight method

353

Implementing Life Cycle Assessment in systems development.  

DEFF Research Database (Denmark)

Today's industry is being forced to consider the environmental performance of its products concurrently with traditional requirements such as quality, price or functional performance. The Life Cycle Assessment (LCA) technique has been identified as a powerful tool to calculate environmental impacts derived from products and system, and calculate resource consumptions. However, the complexity of LCA poses restrictions to its use in current product and system development given the need for a reduction in product development cycle time which is needed to meet the increasing competitive pressures and the rapid changes in markets for many products. The overall aim of the paper is to provide an understanding of the environmental issues involved in the early stages of product development and the capacity of life cycle assessment techniques to address these issues. The paper aims to outline the problems for the designer in evaluating the environmental benignity of the product from the outset and to provide the designer with a framework for decision support based on the performance evaluation at different stages of the design process. The overall aim of this paper is to produce an in-depth understanding of the barriers to implementation of LCA by developers of products, and of the opportunities for introducing environmental criteria in the design process through meeting the information requirements of the designer on the different life cycle stages, producing an in-depth understanding of the attitudes of practitioners among product developers to the subject area, and an understanding of possible future directions for product development. An Environmentally Conscious Design method is introduced and trade-offs are presented between design degrees of freedom and environmental solutions. It also discusses a number of possibilities which can be introduced in the design stage compared to the other life cycle stages of the product system. The paper collects experiences and ideas around the state-of-the-art in eco-design, from literature and personal experience and further provides eco-design life cycle assessment strategies. The paper reviews the current environmental evaluation practices with respect to product life cycles. As a number of deficiencies in LCA are identified, strategies are presented to provide a solution to many of the deficiencies. The result of the paper is a definition of the requirements for performance measurement techniques and a performance measurement environment necessary to support life cycle evaluation throughout the evaluation of early stages of a product system.

Bhander, Gurbakhash Singh; Hauschild, Michael Zwicky

2003-01-01

354

Development of Vertical Cable Seismic System (2)  

Science.gov (United States)

The vertical cable seismic is one of the reflection seismic methods. It uses hydrophone arrays vertically moored from the seafloor to record acoustic waves generated by surface, deep-towed or ocean bottom sources. Analyzing the reflections from the sub-seabed, we could look into the subsurface structure. This type of survey is generally called VCS (Vertical Cable Seismic). Because VCS is an efficient high-resolution 3D seismic survey method for a spatially-bounded area, we proposed the method for the hydrothermal deposit survey tool development program that the Ministry of Education, Culture, Sports, Science and Technology (MEXT) started in 2009. We are now developing a VCS system, including not only data acquisition hardware but data processing and analysis technique. Our first experiment of VCS surveys has been carried out in Lake Biwa, JAPAN in November 2009 for a feasibility study. Prestack depth migration is applied to the 3D VCS data to obtain a high quality 3D depth volume. Based on the results from the feasibility study, we have developed two autonomous recording VCS systems. After we carried out a trial experiment in the actual ocean at a water depth of about 400m and we carried out the second VCS survey at Iheya Knoll with a deep-towed source. In this survey, we could establish the procedures for the deployment/recovery of the system and could examine the locations and the fluctuations of the vertical cables at a water depth of around 1000m. The acquired VCS data clearly shows the reflections from the sub-seafloor. Through the experiment, we could confirm that our VCS system works well even in the severe circumstances around the locations of seafloor hydrothermal deposits. We have carried out two field surveys in 2011. One is a 3D survey with a boomer for a high-resolution surface source and the other one for an actual field survey in the Izena Cauldron an active hydrothermal area in the Okinawa Trough. Through these surveys, we have confirmed that the uncertainty in the locations of the source and of the hydrophones in water could lower the quality of subsurface image. It is, therefore, strongly necessary to develop a total survey system that assures an accurate positioning and a deployment techniques. In case of shooting on sea surface, GPS navigation system are available, but in case of deep-towed source or ocean bottom source, the accuracy of shot position with SSBL/USBL is not sufficient for the very high-resolution imaging as requested for the SMS survey. We will incorporate the accurate LBL navigation systems with VCs. The LBL navigation system has been developed by IIS of the University of Tokyo. The error is estimated less than 10cm at the water depth of 3000m. Another approach is that the shot points can be calculated using the first break of the VCS after the VCS locations are estimated by slant-ranging from the sea surface. Our VCS system has been designed as a survey tool for hydrothermal deposit, but it will be also applicable for deep water site surveys or geohazard assessment such as active faults.

Asakawa, E.; Murakami, F.; Tsukahara, H.; Ishikawa, K.

2012-12-01

355

Master Console System Monitoring and Control Development  

Science.gov (United States)

The Master Console internship during the summer of 2013 involved the development of frring room displays and support applications at the John F. Kennedy Space Center (KSC). This position was with the Master Console Product Group (MCPG) on the Launch Control System (LCS) project. This project is responsible for the System Monitoring and Control (SMC) and Record and Retrieval (R&R) of launch operations data. The Master Console is responsible for: loading the correct software into each of the remaining consoles in the firing room, connecting the proper data paths to and from the launch vehicle and all ground support equipment, and initializing the entire firing room system to begin processing. During my internship, I created control scripts using the Application Control Language (ACL) to analyze the health and status of Kennedy Ground Control System (KGCS) programmable logic controllers (PLCs). This application provides a system health and status display I created with summarized data for use by Master Console Operators (MCO) to monitor and verify the integrity of KGCS subsystems.

Brooks, Russell A.

2013-01-01

356

Development of oral cavity inspecting system  

Science.gov (United States)

An oral cavity inspecting system is designed and developed to inspect the detail of teeth. The inspecting system is composed of microscopic imaging part, illuminating part, image capture and processing, display part. The two groups of cemented lenses were optimized to minimize the optical aberration and the collimated beam light is gotten between the two lenses. A relay lens is adopted to allow the probe to access the oral cavity depth. The illumination optic fiber is used and the brightness and color temperature can be adjustable. The illumination fiber end surface is oblique cut and the optimum angle is 37°. The image of teeth is imaged on CMOS and captured into computer. The illumination intensity and uniformity were tested and the proper parameter is set. Foucault chart was observed and the system resolution is higher than 100lp/mm. The oral inspecting system is used to test standard tooth model and patho-teeth model. The tooth image is clear and the details can be observed. The experimental results show that the system could meet dental medical application requirements.

Zhang, Hongxia; Wu, Di; Jia, Dagong; Zhang, Yimo

2009-11-01

357

Lunar Surface Systems Supportability Technology Development Roadmap  

Science.gov (United States)

The Lunar Surface Systems Supportability Technology Development Roadmap is a guide for developing the technologies needed to enable the supportable, sustainable, and affordable exploration of the Moon and other destinations beyond Earth. Supportability is defined in terms of space maintenance, repair, and related logistics. This report considers the supportability lessons learned from NASA and the Department of Defense. Lunar Outpost supportability needs are summarized, and a supportability technology strategy is established to make the transition from high logistics dependence to logistics independence. This strategy will enable flight crews to act effectively to respond to problems and exploit opportunities in an environment of extreme resource scarcity and isolation. The supportability roadmap defines the general technology selection criteria. Technologies are organized into three categories: diagnostics, test, and verification; maintenance and repair; and scavenge and recycle. Furthermore, "embedded technologies" and "process technologies" are used to designate distinct technology types with different development cycles. The roadmap examines the current technology readiness level and lays out a four-phase incremental development schedule with selection decision gates. The supportability technology roadmap is intended to develop technologies with the widest possible capability and utility while minimizing the impact on crew time and training and remaining within the time and cost constraints of the program.

Oeftering, Richard C.; Struk, Peter M.; Green, Jennifer L.; Chau, Savio N.; Curell, Philip C.; Dempsey, Cathy A.; Patterson, Linda P.; Robbins, William; Steele, Michael A.; DAnnunzio, Anthony; Meseroll, Robert; Quiter, John; Shannon, Russell; Easton, John W.; Madaras, Eric I.; BrownTaminger, Karen M.; Tabera, John T.; Tellado, Joseph; Williams, Marth K.; Zeitlin, Nancy P.

2011-01-01

358

Development and application of earth system models.  

Science.gov (United States)

The global environment is a complex and dynamic system. Earth system modeling is needed to help understand changes in interacting subsystems, elucidate the influence of human activities, and explore possible future changes. Integrated assessment of environment and human development is arguably the most difficult and most important "systems" problem faced. To illustrate this approach, we present results from the integrated global system model (IGSM), which consists of coupled submodels addressing economic development, atmospheric chemistry, climate dynamics, and ecosystem processes. An uncertainty analysis implies that without mitigation policies, the global average surface temperature may rise between 3.5 °C and 7.4 °C from 1981-2000 to 2091-2100 (90% confidence limits). Polar temperatures, absent policy, are projected to rise from about 6.4 °C to 14 °C (90% confidence limits). Similar analysis of four increasingly stringent climate mitigation policy cases involving stabilization of greenhouse gases at various levels indicates that the greatest effect of these policies is to lower the probability of extreme changes. The IGSM is also used to elucidate potential unintended environmental consequences of renewable energy at large scales. There are significant reasons for attention to climate adaptation in addition to climate mitigation that earth system models can help inform. These models can also be applied to evaluate whether "climate engineering" is a viable option or a dangerous diversion. We must prepare young people to address this issue: The problem of preserving a habitable planet will engage present and future generations. Scientists must improve communication if research is to inform the public and policy makers better. PMID:22706645

Prinn, Ronald G

2013-02-26

359

The Mediterranean Forecasting System: recent developments  

Science.gov (United States)

Recent developments of the Mediterranean Monitoring and Forecasting Centre of the EU-Copernicus marine service, the Mediterranean Forecasting System (MFS), are presented. MFS provides forecast, analysis and reanalysis for the physical and biogeochemical parameters of the Mediterranean Sea. The different components of the system are continuously updated in order to provide to the users the best available product. This work is focus on the physical component of the system. The physical core of MFS is composed by an ocean general circulation model (NEMO) coupled with a spectral wave model (Wave Watch-III). The NEMO model provides to WW-III surface currents and SST fields, while WW-III returns back to NEMO the neutral component of the surface drag coefficient. Satellite Sea Level Anomaly observations and in-situ T & S vertical profiles are assimilated into this system using a variational assimilation scheme based on 3DVAR (Dobricic, 2008) . Sensitive experiments have been performed in order to assess the impact of the assimilation of the latest available SLA missions, Altika and Cryosat together with the long term available mission of Jason2. The results show a significant improvement of the MFS skill due to the multi-mission along track assimilation. The primitive equations module has been recently upgraded with the introduction of the atmospheric pressure term and a new, explicit, numerical scheme has been adopted to solve the barotropic component of the equations of motion. The SLA satellite observations for data assimilation have been consequently modified in order to account for the new atmospheric pressure term introduced in the equations. This new system has been evaluated using tide gauge coastal buoys and the satellite along track data. The quality of the SSH has improved significantly while a minor impact has been observed on the other state variables (temperature, salinity and currents). Experiments with a higher resolution NWP (numerical weather prediction) forcing provided by the COSMO-MED system (provided by the Italian Meteorological Office), have been performed and a pre-operational 3-day forecast production system has been developed. The comparison between this system and the official one forced by the ECMWF NWP data will be discussed.

Tonani, Marina; Oddo, Paolo; Korres, Gerasimos; Clementi, Emanuela; Dobricic, Srdjan; Drudi, Massimiliano; Pistoia, Jenny; Guarnieri, Antonio; Romaniello, Vito; Girardi, Giacomo; Grandi, Alessandro; Bonaduce, Antonio; Pinardi, Nadia

2014-05-01

360

Information systems for engineering sustainable development  

Energy Technology Data Exchange (ETDEWEB)

The ability of a country to follow sustainable development paths is determined to a large extent by the capacity or capabilities of its people and its institutions. Specifically, capacity-building in the UNCED terminology encompasses the country's human, scientific, technological, organizational, institutional, and resource capabilities. A fundamental goal of capacity-building is to enhance the ability to pose, evaluate and address crucial questions related to policy choices and methods of implementation among development options. As a result the United Nations Conference on Environment and Development (UNCED) Agenda 21 planning process has identified the need for better methods by which information can be transferred between industrialized nations and developing nations. The reasons for better methods of information transfer include facilitating decisions related to sustainable development and building the capacity of developing nations to better plan their future in both an economical and environmentally sound manner. This paper is a discussion on mechanisms for providing information and technologies available for presenting the information to a variety of cultures and levels of technical literacy. Consideration is given to access to information technology as well as to the cost to the user. One concept discussed includes an Engineering Partnership'' which brings together the talents and resources of private consulting engineers, corporations, non-profit professional organizations, government agencies and funding institution which work in partnership with each other and associates in developing countries. Concepts which are related to information technologies include a hypertext based, user configurable cultural translator and information navigator and the use of multi-media technologies to educate engineers about the concepts of sustainability, and the adaptation of the concept of metabolism to creating industrial systems.

Leonard, R.S.

1992-02-27

 
 
 
 
361

Information systems for engineering sustainable development  

Energy Technology Data Exchange (ETDEWEB)

The ability of a country to follow sustainable development paths is determined to a large extent by the capacity or capabilities of its people and its institutions. Specifically, capacity-building in the UNCED terminology encompasses the country`s human, scientific, technological, organizational, institutional, and resource capabilities. A fundamental goal of capacity-building is to enhance the ability to pose, evaluate and address crucial questions related to policy choices and methods of implementation among development options. As a result the United Nations Conference on Environment and Development (UNCED) Agenda 21 planning process has identified the need for better methods by which information can be transferred between industrialized nations and developing nations. The reasons for better methods of information transfer include facilitating decisions related to sustainable development and building the capacity of developing nations to better plan their future in both an economical and environmentally sound manner. This paper is a discussion on mechanisms for providing information and technologies available for presenting the information to a variety of cultures and levels of technical literacy. Consideration is given to access to information technology as well as to the cost to the user. One concept discussed includes an ``Engineering Partnership`` which brings together the talents and resources of private consulting engineers, corporations, non-profit professional organizations, government agencies and funding institution which work in partnership with each other and associates in developing countries. Concepts which are related to information technologies include a hypertext based, user configurable cultural translator and information navigator and the use of multi-media technologies to educate engineers about the concepts of sustainability, and the adaptation of the concept of metabolism to creating industrial systems.

Leonard, R.S.

1992-02-27

362

Flammability test for sunglasses: developing a system  

Science.gov (United States)

Recent investigations show the need for certificating sunglasses to ensure the safety and health to population. The Brazilian Standard ABNT NBR 15111 regulates features to sunglasses, however, there is not a sunglasses certification office in Brazil, therefore, our lab has been developing several equipment for sunglasses testing. This work refers to one of them: the flammability test system for sunglasses in compliance with the NBR 15111. The standard provides requirements for the flammability test procedure which requires that the equipment must operate at a temperature of 650 °C +/- 20 °C the end of a steel rod of 300 mm length and 6 mm diameter should be heated and pressed over the surface of the lenses for five seconds; the flammability is checked by visual inspection. The furnace is made of ceramic. We used a power electronic circuit to control the power in the furnace using ON/OFF mode and for measuring the temperature, we used a K-type thermocouple. A stepper motor with pulley lifts the steel rod. The system reaches the working temperature in 15 minutes for a step input of 61 V in open loop system. The electronics control are under development in order to shorten the time necessary to reach the working temperature and maintain the temperature variation in the furnace within the limits imposed by the standard as next steps.

Magri, Renan; Ventura, Liliane

2014-02-01

363

EU developments of the ITER ECRH system  

Energy Technology Data Exchange (ETDEWEB)

The EU will be providing the largest contribution to the ITER electron cyclotron (EC) heating and current drive (H and CD) system (20 MW, CW at 170 GHz). The contribution includes one third of the H and CD gyrotrons, their associated power supplies and four upper port launcher antennas. In all areas of participation, the EU EC partnership (coordinated by the European Fusion Development Agreement) aims toward advancing the technology, while staying within a specified cost envelope. This is portrayed in the co-axial gyrotron development that offers the potential to double the output power per source (2.0 MW), increasing the delivered power for a fixed number of auxiliary systems. The EU partnerships also attempt to increase performance for the entire EC system, in particular the launching antennas. The proposed front steering launcher design offers greater control of MHD activity than the previous remote steering design and opens up the possibility of an enhanced performance UL. The EC physics requirements are repartitioned between the upper and equatorial launchers for a synergetic balance, which increases the EC physics capabilities while relaxing some of the engineering requirements.

Henderson, M.A. [CRPP, EURATOM Confdration Suisse, EPFL, CH-1015 Lausanne (Switzerland)], E-mail: mark.henderson@epfl.ch; Alberti, S. [CRPP, EURATOM Confdration Suisse, EPFL, CH-1015 Lausanne (Switzerland); Benin, P. [Thales Electron Devices (TED), F-78141 Vlizy-Villacoublay (France); Bonicelli, T. [EFDA Close Support Unit, Boltzmannstrasse 2, D-85748 Garching (Germany); Chavan, R. [CRPP, EURATOM Confdration Suisse, EPFL, CH-1015 Lausanne (Switzerland); Campbell, D. [EFDA Close Support Unit, Boltzmannstrasse 2, D-85748 Garching (Germany); Cirant, S. [Istituto di Fisica del Plasma, EURATOM- ENEA- CNR, 20125 Milan (Italy); Dammertz, G. [Forschungszentrum Karlsruhe, IHM, EURATOM-FZK, D-76021 Karlsruhe (Germany); Dormicchi, O. [ANSALDO, I-16152, Genova (Italy); Dumbrajs, O. [HUT Helsinki, EURATOM TEKES, FIN-02150 Espoo (Finland); Fasel, D.; Goodman, T.P. [CRPP, EURATOM Confdration Suisse, EPFL, CH-1015 Lausanne (Switzerland); Heidinger, R. [Forschungszentrum Karlsruhe, IHM, EURATOM-FZK, D-76021 Karlsruhe (Germany); Hogge, J.-P. [CRPP, EURATOM Confdration Suisse, EPFL, CH-1015 Lausanne (Switzerland); Kasparek, W. [Institut fur Plasmaphysik, EURATOM IPP, D-70569 Stuttgart (Germany); Lievin, C. [Thales Electron Devices (TED), F-78141 Vlizy-Villacoublay (France); Piosczyk, B. [Forschungszentrum Karlsruhe, IHM, EURATOM-FZK, D-76021 Karlsruhe (Germany); Poli, E. [Max Planck-Institute fur Plasmaphysik, EURATOM-IPP, D-85748 Garching (Germany); Ramponi, G. [Istituto di Fisica del Plasma, EURATOM- ENEA- CNR, 20125 Milan (Italy); Saibene, G. [EFDA Close Support Unit, Boltzmannstrasse 2, D-85748 Garching (Germany)] (and others)

2007-10-15

364

Advanced systems: Status and development prospects  

International Nuclear Information System (INIS)

World reserves of coal, uranium, thorium and thermonuclear fuel (deuterium and lithium) are sufficient to provide mankind with energy for many centuries. The rate of increase in demand is unlikely to be a limiting factor, and it would seem that any ''limits to growth'' will be dictated by other, in particular ecological, factors. In the last two decades, world power production has developed a structure in which a predominant place is occupied by oil and gas; this will have to change as a result of the marked depletion of oil resources and the enhanced role played in the fuel balance by power from coal and nuclear fission, on which, it would seem, the long-term growth of world energy production will be based. The contribution of nuclear fission power towards meeting world energy needs will depend on a number of factors, the most important of which from a long-term point of view is the time and rate of introduction of advanced nuclear power systems and fuel cycles with high nuclear fuel surpluses (breeding ratios). The results of almost 30 years of development of nuclear power with thermal-neutron reactors may serve as a basis for the analysis, evaluation and forecasting of the development of advanced systems. (author)

365

Development of the plutonium oxide vitrification system  

Energy Technology Data Exchange (ETDEWEB)

Repository disposal of plutonium in a suitable, immobilized form is being considered as one option for the disposition of surplus weapons-usable plutonium. Accelerated development efforts were completed in 1997 on two potential immobilization forms to facilitate downselection to one form for continued development. The two forms studied were a crystalline ceramic based on Synroc technology and a lanthanide borosilicate (LaBS) glass. As part of the glass development program, melter design activities and component testing were completed to demonstrate the feasibility of using glass as an immobilization medium. A prototypical melter was designed and built in 1997. The melter vessel and drain tube were constructed of a Pt/Rh alloy. Separate induction systems were used to heat the vessel and drain tube. A Pt/Rh stirrer was incorporated into the design to facilitate homogenization of the melt. Integrated powder feeding and off-gas systems completed the overall design. Concurrent with the design efforts, testing was conducted using a plutonium surrogate LaBS composition in an existing (near-scale) melter to demonstrate the feasibility of processing the LaBS glass on a production scale. Additionally, the drain tube configuration was successfully tested using a plutonium surrogate LaBS glass.

Marshall, K.M.; Marra, J.C.; Coughlin, J.T.; Calloway, T.B.; Schumacher, R.F.; Zamecnik, J.R.; Pareizs, J.M.

1998-01-01

366

The Importance of Detailed Component Simulations in the Feedsystem Development for a Two-Stage-to Orbit Reusable Launch Vehicle  

Science.gov (United States)

To meet the requirements for the 2nd Generation Reusable Launch Vehicle (RLV), a unique propulsion feed system concept was identified using crossfeed between the booster and orbiter stages that could reduce the Two-Stage-to-Orbit (TSTO) vehicle weight and development cost by approximately 25%. A Main Propulsion System (MPS) crossfeed water demonstration test program was configured to address all the activities required to reduce the risks for the MPS crossfeed system. A transient, one-dimensional system simulation was developed for the subscale crossfeed water flow tests. To ensure accurate representation of the crossfeed valve's dynamics in the system model, a high-fidelity, three-dimensional, computational fluid-dynamics (CFD) model was employed. The results from the CFD model were used to specify the valve's flow characteristics in the system simulation. This yielded a crossfeed system model that was anchored to the specific valve hardware and achieved good agreement with the measured test data. These results allowed the transient models to be correlated and validated and used for full scale mission predictions. The full scale model simulations indicate crossfeed is ' viable with the system pressure disturbances at the crossfeed transition being less than experienced by the propulsion system during engine start and shutdown transients.

Mazurkivich, Pete; Chandler, Frank; Grayson, Gary

2005-01-01

367

Pulmonary targeting microparticulate camptothecin delivery system: anticancer evaluation in a rat orthotopic lung cancer model.  

Science.gov (United States)

Large (>6 microm) rigid microparticles (MPs) become passively entrapped within the lungs after intravenous (i.v.) injection making them an attractive and highly efficient alternative to inhalation for pulmonary delivery. In this study, PEGylated 6 microm polystyrene MPs with multiple copies of the norvaline (Nva) alpha-amino acid prodrug of camptothecin (CPT) were prepared. Surface morphology was characterized using a scanning electron microscope. CPT was released from the CPT-Nva-MPs over 24 h in rat plasma at 37 degrees C. In-vivo CPT plasma concentrations were low (approximately 1 ng/ml or less) and constant over a period of 4 days after a single i.v. injection of CPT-Nva-MPs as compared with high but short-lived systemic exposures after an i.v. injection of free CPT. This suggests that sustained local CPT concentrations were achieved in the lung after administration of the MP delivery system. Anticancer efficacy was evaluated in an orthotopic lung cancer animal model and compared with a bolus injection of CPT. Animals receiving free CPT (2 mg/kg) and CPT-Nva-MPs (0.22 mg/kg CPT and 100 mg/kg MPs) were found to have statistically significant smaller areas of lung cancer (P<0.05 and 0.01, respectively) than untreated animals. In addition, 40% of the animals receiving CPT-Nva-MPs were found to be free of cancer. The CPT dose using targeted MPs was 10 times lower than after i.v. injection of free CPT, but was more effective in reducing the amount of cancerous areas. In conclusion, CPT-Nva-MPs were able to achieve effective local lung and low systemic CPT concentrations at a dose that was 10 times lower than systemically administered CPT resulting in a significant improvement in anticancer efficacy in an orthotopic rat model of lung cancer. PMID:19966540

Chao, Piyun; Deshmukh, Manjeet; Kutscher, Hilliard L; Gao, Dayuan; Rajan, Sujata Sundara; Hu, Peidi; Laskin, Debra L; Stein, Stanley; Sinko, Patrick J

2010-01-01

368

Development of the power system for accelerator  

International Nuclear Information System (INIS)

The 100-MeV proton linac needs 4 modulators whose specification is as follows, -115kV, 55A, and 9%. The development of the modulators were successfully finished and installed at Gyeongju site of KAERI. One of them was used and successfully tested in the 20-MeV linac operation at Daejeon site. The klystron is used to supply the high power RF into the accelerating structure. There are 2 klystrons for 20-MeV part of the linac and 7 klystrons from 20-MeV to 100-MeV region. The maximum voltage is ?105kV, the peak power is 1.6 MW, and the duty is 9%. All of the 7 klystrons have been fabricated, tested and installed. The high power RF system includes circulators, dummy lodes, RF windows, and wave-guides. The development of the high power RF components was finished and they were installed at the Gyeongju site. The 11 sets of RCCS (resonant control cooling system) will be used to control the cooling water temperature inside the accelerating structure. The temperature range of the cooling water covers between 21 .deg. C and 33 .deg. C with the 0.1 .deg. C control. All RCCSs were installed in the klystron gallery. Purposes of the 20-MeV linac operation at Daejeon site of KAERI (2007?2011) are to supply proton beams to user, to porve the accelerator performance, to test the developed components including LLRF, diagnostics, and control system, and to measure the proton beam properties. During the period, the total number of samples reaches to 1,603 and the average machine availability becomes 96.2%. The 20-MeV linac was disassembled, moved and installed at Gyeongju site after finishing the test operation

369

Development of an automated microbial sensor system.  

Science.gov (United States)

An automated whole cell biosensor system was developed by integration of immobilized microbial cells in a flow-through system with screen-printed flow-through electrodes as detectors. The detectors used were thick-film Pt-electrodes in a 3-electrode configuration constructed as sandwich flow-through cells with a volume of about 36 microliters polarized at -900 mV. The measuring principle was the determination of oxygen consumption due to the microbial metabolism. Fructose was used as model analyte. The microorganisms were immobilized on cellulose-acetate membranes and integrated into a newly created reaction chamber (membrane reactor). The microbial cells used were Rhodococcus erythropolis and Issatchenkia orientalis known to be suitable for the determination of biological oxygen demand. PMID:10101840

Heim, S; Schnieder, I; Binz, D; Vogel, A; Bilitewski, U

1999-02-01

370

NANOTECHNOLOGY IN DEVELOPMENT OF DRUG DELIVERY SYSTEM  

Directory of Open Access Journals (Sweden)

Full Text Available Nanotechnology is science of matter and material that deal with particle size in nanometers. Nanotechnology has received a lot of attention with never-seen-before enthusiasm because of its future potential. It has provided fine lined diagnosis and focus treatment of disease at molecular level. This technology offers the advantage of protecting drugs from degradation; reduce the number of doses required. In this review, a discussion was carried out on different techniques for the preparation of nanodrug delivery systems like nanoparticles, solid lipid nanoparticles, nanocrystals, nanosuspensions, nanoemulsions. The concept of nanotechnology is widely expanded and applied to many drugs to the present. The ultimate application goal of nano drug delivery system is to develop clinically useful formulation for treating diseases in patients.

Vidyavathi Maravajhala et al.

2012-01-01

371

Development of a microbeam scanning system  

International Nuclear Information System (INIS)

High energy ion microbeam is a powerful analytical tool by combining various ion beam analysis techniques and is also attractive as a direct lithographic technique. We have developed a microbeam scanning system which is indispensable to these purposes. The scanning system is composed of a set of electrostatic deflectors, HV amplifiers and a function generator. Microbeams are scanned with a corresponding scanning pattern translated from a bitmap file for an efficient irradiation. The spacing between patterns to pattern was made by moving the beam at the fastest speed of the beam scanner. The irradiation dose was monitored pixel by pixel with RBS. The technique is applicable to an efficient ion beam analysis by combining STIM image. (author)

372

DEVELOPMENT AND MARKET OF ERP SYSTEMS  

Directory of Open Access Journals (Sweden)

Full Text Available The business environment’s changes occurring more and more quickly and company activities’ becoming more and more complex require permanent, fast adjustments which often test human factors’ abilities for efforts and analyses. The creation and development of ERP-type systems have been and are still believed to be the solutions of such challenges ensuring certain support to process large amounts of data and information needed in companies’ decision-making processes. An ERP system helps the integration of a company’s set of information into a single platform due to the way in which it succeeds in combining business management techniques and practices with the new information technology, providing the transparency of data and the access to the necessary information.

DIANA-ELENA CODREANU

2012-11-01

373

Development of hybrid hydrogen control system  

International Nuclear Information System (INIS)

Catalytic recombiners disposing of hydrogen in severe accidents of nuclear power plants generally has a weak property for poison and steam environment. Spherical catalyst is robust for poison because of porosity with large specific area, but relatively weak for steam because of easily condensing steam by capillary phenomenon. Plate-type catalyst is conversely thought to be robust for steam but weak for poison. Hybrid hydrogen control system that consists of catalytic layers filled with spherical catalyst, barlike heater penetrating catalytic layers and covering box improves weakness of spherical catalyst by heating and also has function of an igniter. We first investigated the relation between resistance to steam and material sort with diameter of spherical catalyst to develop hybrid hydrogen control system. We verified that Pt in a small diameter was superior as recombiner catalyst. We successively carried out integrated tests by optimized catalytic layer shape to verily performance of hybrid hydrogen control system as a recombiner and an igniter. Hybrid hydrogen control system is prospected to be applied to commercial nuclear power plants. (author)

374

Developments towards a fully automated AMS system  

Science.gov (United States)

The possibilities of computer-assisted and automated accelerator mass spectrometry (AMS) measurements were explored. The goal of these efforts is to develop fully automated procedures for "routine" measurements at the Vienna Environmental Research Accelerator (VERA), a dedicated 3-MV Pelletron tandem AMS facility. As a new tool for automatic tuning of the ion optics we developed a multi-dimensional optimization algorithm robust to noise, which was applied for 14C and 10Be. The actual isotope ratio measurements are performed in a fully automated fashion and do not require the presence of an operator. Incoming data are evaluated online and the results can be accessed via Internet. The system was used for 14C, 10Be, 26Al and 129I measurements.

Steier, P.; Puchegger, S.; Golser, R.; Kutschera, W.; Priller, A.; Rom, W.; Wallner, A.; Wild, E.

2000-03-01

375

Development techniques of computerized maintenance Management system  

Energy Technology Data Exchange (ETDEWEB)

Normal operation of the facility is one of the key factors in the accomplishments of research goals. As confirmed by a case study of the influence of the facility operation condition on the research results, emphasis should be put on the facility preserve management. Facilities should be maintained in solid operational condition and their malfunctions should be repaired as soon as possible. The purpose of this project is to make propositions on the development of the facility preserve management system which is to maximize the efficiency of the budget execution, manpower organization and maintenance planning, and is to minimize the duration of the operational pause due to malfunctions with the least disbursement.

Oh, Yon Woo; Kim, S.D.; Soong, W.S.; Kim, G.H.; Oh, W.H.; Kim, Y.G

2000-05-01

376

Development techniques of computerized maintenance Management system  

International Nuclear Information System (INIS)

Normal operation of the facility is one of the key factors in the accomplishments of research goals. As confirmed by a case study of the influence of the facility operation condition on the research results, emphasis should be put on the facility preserve management. Facilities should be maintained in solid operational condition and their malfunctions should be repaired as soon as possible. The purpose of this project is to make propositions on the development of the facility preserve management system which is to maximize the efficiency of the budget execution, manpower organization and maintenance planning, and is to minimize the duration of the operational pause due to malfunctions with the least disbursement

377

Development of the High Energy Linac Systems  

International Nuclear Information System (INIS)

The main purpose of this project is studying the extension plan of the proton engineering frontier project (PEFP) 100-MeV Linac. It includes three categories. One is studying operation plan of the PEFP linac and its extended accelerators, and developing a distribution system of 100-MeV proton beams with a laser striping. Other is designing superconducting RF (SRF) modules and fabricating and testing a copper cavity model. The other is designing a rapid cycling synchrotron (RCS). The operation scheme of the PEFP linac is related to the optimization in the operation of the 100-MeV linac, 200-MeV SRF, and RCS. We studied several operational method to increase the validity of the accelerators. The beam distribution system has two roles. One is supplying proton beams of 100 MeV to the user group. The laser stripping of the negative hydrogen atoms is used in this case. The other beams are directed to the next high energy accelerators. This study contributes to increase the availability of the proton beams. The SRF is one of candidates to extend the PEFP linac system. Since the accelerating gradient of the SRF is much higher than the normal conducting accelerator, a lot of institutes over the world are developing the SRF structure. Main purposes are designing an SRF module, fabricating and testing an copper model which has similar material properties as Nb of the usual SRF cavity material. The RCS is a synchrotron whose injector is the PEFP 100-MeV linac. Main purposes are determining the lattice structure, studying the fast and slow extraction system, simulating beam behavior in the designed synchrotron. The RCS will be used as the spallation neutron source and tools in the basic and applied science including medical application

378

Developing management systems for emerging countries  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese A aplicação das teorias de gestão de países industrializados em diferentes contextos tem sido questionada por muitas décadas. No entanto, ainda não há fundamentação teórica bem definida para compreensão dos sistemas de gestão dos países não-industrializados. Este artigo, ao detalhar as característic [...] as das estratégias, das estruturas, dos processos decisórios e dos sistemas de gestão em países em desenvolvimento, fornece algumas diretrizes para o desenvolvimento das teorias de gestão desses países. A análise evidenciou que a complexidade das forças ambientais dos países em desenvolvimento tem dificultado a aplicação das teorias de gestão importadas dos países industrializados. O artigo conclui que as organizações globais devem parar de tentar transferir e adaptar esses sistemas de gestão para os países em desenvolvimento e que uma abordagem clínica pode ser mais efetiva. Abstract in english Application of Western management theories in different contexts has been questioned for several decades. However, there is still no well-defined theoretical framework for understanding management systems in non-industrialized countries. This article provides some guidelines to develop these framewo [...] rks by elaborating some of the major characteristics of strategies, structures, decision-makings and management systems in Developing Countries (DC). The analysis showed evidence that the complexity of national environmental forces of DCs has made the application of Western management theories more problematic in these countries. The article concludes that global business firms should realize that it is time to stop transferring these management systems to DCs and trying to adapt their organizations to these systems and that a clinical type of approach may be more effective.

Jorge Miguel, Carrillo.

379

Program Director, AD-1321-4 MPS/DMR (Closes: 07/01/2005)  

Science.gov (United States)

... groups, centers, national facilities, and instrumentation. Individual investigator and group ... and combined experiment and theory projects on the physics of solid, liquid, and amorphous systems ...

380

Development of a new airborne humidigraph system.  

Energy Technology Data Exchange (ETDEWEB)

Modeling and measurements of aerosol properties is complicated by the hygroscopic behavior of the aerosols adding significant uncertainty to our best estimates of the direct effect aerosols exert on the radiative balance of the atmosphere. Airborne measurements of aerosol hygroscopicity are particularly challenging but critically needed. This motivated the development of a newly designed system which can measure the dependence of the aerosol light scattering coefficient (?sp) on relative humidity (RH), known as f(RH), in real-time at a rapid rate (<10 s) on an aerial platform. The new system has several advantages over existing systems. It consists of three integrating nephelometers and humidity conditioners for simultaneous measurement of the ?sp at three different RHs. The humidity is directly controlled in exchanger cells without significant temperature disturbances and without particle dilution, heating or loss of volatile compounds. The single-wavelength nephelometers are illuminated by LED-based light sources thereby minimizing heating of the sample stream. The flexible design of the RH conditioners, consisting of a number of specially designed exchanger cells (driers or humidifiers), enables us to measure f(RH) under hydration or dehydration conditions (always starting with the aerosol in a known state) with a simple system re-configuration. These exchanger cells have been characterized for losses of particles using latex spheres and laboratory generated ammonium sulfate aerosols. Residence times of 6 - 9 s in the exchangers and subsequent lines is sufficient for most aerosols to attain equilibrium with the new water vapor content. The performance of this system has been assessed aboard DOE’s G-1 research aircraft during test flights over California, Oregon, and Washington.

Pekour, Mikhail S.; Schmid, Beat; Chand, Duli; Hubbe, John M.; Kluzek, Celine D.; Nelson, Danny A.; Tomlinson, Jason M.; Cziczo, Daniel J.

2012-12-06

 
 
 
 
381

Program Director Astronomer AD 1330-04 MPS/AST (Closes: 04/15/2005)  

Science.gov (United States)

... astronomy in the U.S. AST supports the development and operation of four National Astronomy ... Astronomy Observatory (NOAO), the National Solar Observatory (NSO), the National Radio Astronomy ...

382

Program Director, AD-1301-4, MPS/AST (Closes: 09/30/2005)  

Science.gov (United States)

... astronomy in the U.S. AST supports the development and operation of four National Astronomy ... Astronomy Observatory (NOAO), the National Solar Observatory (NSO), the National Radio Astronomy ...

383

Program Director, AD-1301-4, MPS/AST (Closes: 04/15/2005)  

Science.gov (United States)

... astronomy in the U.S. AST supports the development and operation of four National Astronomy ... Astronomy Observatory (NOAO), the National Solar Observatory (NSO), the National Radio Astronomy ...

384

SYSTEMS BIOLOGY MODEL DEVELOPMENT AND APPLICATION  

Science.gov (United States)

System biology models holistically describe, in a quantitative fashion, the relationships between different levels of a biologic system. Relationships between individual components of a system are delineated. System biology models describe how the components of the system inter...

385

Development of NRU reflector wall inspection system  

Energy Technology Data Exchange (ETDEWEB)

In 2009 May, the National Research Universal (NRU) calandria leaked. During the next year, the calandria was inspected with six new Non-Destructive Evaluation (NDE) techniques to determine the extent of the corrosion, repaired, and finally the repair was inspected with four additional new NDE techniques before the reactor was returned to service. The calandria is surrounded by a light-water reflector vessel fabricated from the same material as the calandria vessel. Concerns that the same corrosion mechanism had damaged the reflector vessel led to the development of a system to inspect the full circumference of the reflector wall for corrosion damage. The inspection region could only be accessed through 64 mm diameter ports, was 10 m below the port, and had to be inspected from the corroded surface. The ultrasonic technique was designed to produce a closely spaced wall thickness (WT) grid over an area of approximately 5 m2 on the corroded surface using a very small probe holder. This paper describes the Reflector Wall Inspection (RWI) development project and the system that resulted. (author)

Lumsden, R.H.; Luloff, B.V.; Zahn, N.; Simpson, N., E-mail: lumsdenr@aecl.ca [Atomic Energy of Canada Limited, Chalk River, Ontario (Canada)

2013-06-15

386

Development of NRU reflector wall inspection system  

International Nuclear Information System (INIS)

In 2009 May, the National Research Universal (NRU) calandria leaked. During the next year, the calandria was inspected with six new Non-Destructive Evaluation (NDE) techniques to determine the extent of the corrosion, repaired, and finally the repair was inspected with four additional new NDE techniques before the reactor was returned to service. The calandria is surrounded by a light-water reflector vessel fabricated from the same material as the calandria vessel. Concerns that the same corrosion mechanism had damaged the reflector vessel led to the development of a system to inspect the full circumference of the reflector wall for corrosion damage. The inspection region could only be accessed through 64 mm diameter ports, was 10 m below the port, and had to be inspected from the corroded surface. The ultrasonic technique was designed to produce a closely spaced wall thickness (WT) grid over an area of approximately 5 m2 on the corroded surface using a very small probe holder. This paper describes the Reflector Wall Inspection (RWI) development project and the system that resulted. (author)

387

Development of a versatile digital readout system  

International Nuclear Information System (INIS)

During the research and design phase of new detector electronics, development of a suitable test environment takes a significant amount of time. Most existing systems are specifically designed for certain frontend electronics and cannot be reused for future developments. Thus, our approach is to build a flexible test environment with state-of-the-art hardware, which can be reconfigured to support various frontend electronics. This is achieved by deploying a modular design concept, which is followed in both hardware and software. Key features of the hardware platform are the gigabit optical connection to the PC, the powerful FPGA (Virtex 4), and consequent separation of analog and digital parts of the readout. Via firmware updates, arbitrary communication protocols can be implemented and the external connectors of the readout board can be freely configured. This is accompanied by a modular software framework written in C++ which declares different communication layers for easy hardware access as well as a generic storage structure for simple data handling. These levels of abstraction make it easy to add support for changed or completely new devices. The implementation of the digital readout system as well as its modular firmware and software design is presented and its key features are explained in detail.

388

Wind Development on Tribal Lands  

Energy Technology Data Exchange (ETDEWEB)

Background: The Rosebud Sioux Tribe (RST) is located in south central South Dakota near the Nebraska border. The nearest community of size is Valentine, Nebraska. The RST is a recipient of several Department of Energy grants, written by Distributed Generation Systems, Inc. (Disgen), for the purposes of assessing the feasibility of its wind resource and subsequently to fund the development of the project. Disgen, as the contracting entity to the RST for this project, has completed all the pre-construction activities, with the exception of the power purchase agreement and interconnection agreement, to commence financing and construction of the project. The focus of this financing is to maximize the economic benefits to the RST while achieving commercially reasonable rates of return and fees for the other parties involved. Each of the development activities required and its status is discussed below. Land Resource: The Owl Feather War Bonnet 30 MW Wind Project is located on RST Tribal Trust Land of approximately 680 acres adjacent to the community of St. Francis, South Dakota. The RST Tribal Council has voted on several occasions for the development of this land for wind energy purposes, as has the District of St. Francis. Actual footprint of wind farm will be approx. 50 acres. Wind Resource Assessment: The wind data has been collected from the site since May 1, 2001 and continues to be collected and analyzed. The latest projections indicate a net capacity factor of 42% at a hub height of 80 meters. The data has been collected utilizing an NRG 9300 Data logger System with instrumentation installed at 30, 40 and 65 meters on an existing KINI radio tower. The long-term annual average wind speed at 65-meters above ground level is 18.2 mph (8.1 mps) and 18.7 mph (8.4 mps) at 80-meters agl. The wind resource is excellent and supports project financing.

Ken Haukaas; Dale Osborn; Belvin Pete

2008-01-18

389

Development and Control of a Non Linear Magnetic Levitation System  

Directory of Open Access Journals (Sweden)

Full Text Available Nowadays, studies to develop and control non linear systems is of great significance. Magnetic Levitation System has gained considerable interests due to its great practical importance in different engineering fields In this paper an electromagnetic levitation system was developed and mathematical model for the system was derived. The developed system was controlled manually.

A Sanjeevi Gandhi

2013-06-01

390

Development and Control of a Non Linear Magnetic Levitation System  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Nowadays, studies to develop and control non linear systems is of great significance. Magnetic Levitation System has gained considerable interests due to its great practical importance in different engineering fields In this paper an electromagnetic levitation system was developed and mathematical model for the system was derived. The developed system was controlled manually.

Sanjeevi Gandhi, A.; Reshma Angelene Jose

2013-01-01

391

Power Systems Development Facility. Environmental Assessment  

Energy Technology Data Exchange (ETDEWEB)

The objective of the PSDF would be to provide a modular facility which would support the development of advanced, pilot-scale, coal-based power systems and hot gas clean-up components. These pilot-scale components would be designed to be large enough so that the results can be related and projected to commercial systems. The facility would use a modular approach to enhance the flexibility and capability for testing; consequently, overall capital and operating costs when compared with stand-alone facilities would be reduced by sharing resources common to different modules. The facility would identify and resolve technical barrier, as well as-provide a structure for long-term testing and performance assessment. It is also intended that the facility would evaluate the operational and performance characteristics of the advanced power systems with both bituminous and subbituminous coals. Five technology-based experimental modules are proposed for the PSDF: (1) an advanced gasifier module, (2) a fuel cell test module, (3) a PFBC module, (4) a combustion gas turbine module, and (5) a module comprised of five hot gas cleanup particulate control devices. The final module, the PCD, would capture coal-derived ash and particles from both the PFBC and advanced gasifier gas streams to provide for overall particulate emission control, as well as to protect the combustion turb