WorldWideScience

Sample records for sample media releases

  1. Comparison of in vitro histamine release by ionic and nonionic radiographyic contrast media

    International Nuclear Information System (INIS)

    Faraj, B.A.; Martin, L.G.

    1989-01-01

    This paper discusses a study whose results showed that in 53 hospitalized patients undergoing cardiovascular catheterization, incubation of their blood samples with varying concentrations of an ionic contrast medium (Angiovist-370, 60--631 mM) induced a significant (P < .005) amount of histamine release from whole blood (3.5%--10%), as compared with the histamine release following incubation with a nonionic contrast medium. Data suggest that the use of nonionic contrast media may induce minimal histamine release and thereby involve less patient risk from the histamine-mediated allergic and hemodynamic side effects associated with radiographic contrast media procedures

  2. Development of activated charcoal impregnated air sampling filter media : their characteristics and use

    International Nuclear Information System (INIS)

    Khan, A.A.; Ramarathinam, K.; Gupta, S.K.; Deshingkar, D.S.; Kishore, A.G.

    1975-01-01

    Because of its low maximum permissible concentration in air, air-borne radioiodine must be accurately monitored in contaminated air streams, in the working environment and handling facilities, before release to the environment from the nuclear facilities. Activated charcoal impregnated air sampling filter media are found to be most suitable for monitoring airborne iodine-131. Because of its simplicity and reproducible nature in assessment of air-borne radioactive iodine, the work on the development of such media was undertaken in order to find a suitable substitute for imported activated charcoal impregnated air sampling filter media. Eight different media of such type were developed, evaluated and compared with two imported media. Best suitable medium is recommended for its use in air-borne iodine sampling which was found to be even better suited than imported media of such type. (author)

  3. Corporate Social Responsibility Issues in Media Releases: A Stakeholder Analysis of Australian Banks

    Directory of Open Access Journals (Sweden)

    Christopher J. Reinig

    2008-12-01

    Full Text Available This paper investigates Australia's four major national banks, analysing the use of media releases in the marketing and communication of corporate social responsibility (CSR. Using content analysis, the extent and nature of the media releases issued in 2006, and aimed at specific stakeholders, is determined for each bank. The findings indicate that over one-third of the banks' media releases discuss CSR, predominantly communicating issues related to community involvement. Furthermore, customers and communities are found to be the intended audiences for the majority of the CSR-related media releases.

  4. Assessing the influence of media composition and ionic strength on drug release from commercial immediate-release and enteric-coated aspirin tablets.

    Science.gov (United States)

    Karkossa, Frank; Klein, Sandra

    2017-10-01

    The objective of this test series was to elucidate the importance of selecting the right media composition for a biopredictive in-vitro dissolution screening of enteric-coated dosage forms. Drug release from immediate-release (IR) and enteric-coated (EC) aspirin formulations was assessed in phosphate-based and bicarbonate-based media with different pH, electrolyte composition and ionic strength. Drug release from aspirin IR tablets was unaffected by media composition. In contrast, drug release from EC aspirin formulations was affected by buffer species and ionic strength. In all media, drug release increased with increasing ionic strength, but in bicarbonate-based buffers was delayed when compared with that in phosphate-based buffers. Interestingly, the cation species in the dissolution medium had also a clear impact on drug release. Drug release profiles obtained in Blank CarbSIF, a new medium simulating pH and average ionic composition of small intestinal fluid, were different from those obtained in all other buffer compositions studied. Results from this study in which the impact of various media parameters on drug release of EC aspirin formulations was systematically screened clearly show that when developing predictive dissolution tests, it is important to simulate the ionic composition of intraluminal fluids as closely as possible. © 2017 Royal Pharmaceutical Society.

  5. 14 CFR 1213.106 - Preventing release of classified information to the media.

    Science.gov (United States)

    2010-01-01

    ... ADMINISTRATION RELEASE OF INFORMATION TO NEWS AND INFORMATION MEDIA § 1213.106 Preventing release of classified... interviews, audio/visual) to the news media is prohibited. The disclosure of classified information to unauthorized individuals may be cause for prosecution and/or disciplinary action against the NASA employee...

  6. Social media release increases dissemination of original articles in the clinical pain sciences.

    Science.gov (United States)

    Allen, Heidi G; Stanton, Tasha R; Di Pietro, Flavia; Moseley, G Lorimer

    2013-01-01

    A barrier to dissemination of research is that it depends on the end-user searching for or 'pulling' relevant knowledge from the literature base. Social media instead 'pushes' relevant knowledge straight to the end-user, via blogs and sites such as Facebook and Twitter. That social media is very effective at improving dissemination seems well accepted, but, remarkably, there is no evidence to support this claim. We aimed to quantify the impact of social media release on views and downloads of articles in the clinical pain sciences. Sixteen PLOS ONE articles were blogged and released via Facebook, Twitter, LinkedIn and ResearchBlogging.org on one of two randomly selected dates. The other date served as a control. The primary outcomes were the rate of HTML views and PDF downloads of the article, over a seven-day period. The critical result was an increase in both outcome variables in the week after the blog post and social media release. The mean ± SD rate of HTML views in the week after the social media release was 18±18 per day, whereas the rate during the other three weeks was no more than 6±3 per day. The mean ± SD rate of PDF downloads in the week after the social media release was 4±4 per day, whereas the rate during the other three weeks was less than 1±1 per day (psocial media reach, engagement or virality related to either outcome variable, nor to citation count one year later (p>0.3 for all). We conclude that social media release of a research article in the clinical pain sciences increases the number of people who view or download that article, but conventional social media metrics are unrelated to the effect.

  7. Social media release increases dissemination of original articles in the clinical pain sciences.

    Directory of Open Access Journals (Sweden)

    Heidi G Allen

    Full Text Available A barrier to dissemination of research is that it depends on the end-user searching for or 'pulling' relevant knowledge from the literature base. Social media instead 'pushes' relevant knowledge straight to the end-user, via blogs and sites such as Facebook and Twitter. That social media is very effective at improving dissemination seems well accepted, but, remarkably, there is no evidence to support this claim. We aimed to quantify the impact of social media release on views and downloads of articles in the clinical pain sciences. Sixteen PLOS ONE articles were blogged and released via Facebook, Twitter, LinkedIn and ResearchBlogging.org on one of two randomly selected dates. The other date served as a control. The primary outcomes were the rate of HTML views and PDF downloads of the article, over a seven-day period. The critical result was an increase in both outcome variables in the week after the blog post and social media release. The mean ± SD rate of HTML views in the week after the social media release was 18±18 per day, whereas the rate during the other three weeks was no more than 6±3 per day. The mean ± SD rate of PDF downloads in the week after the social media release was 4±4 per day, whereas the rate during the other three weeks was less than 1±1 per day (p0.3 for all. We conclude that social media release of a research article in the clinical pain sciences increases the number of people who view or download that article, but conventional social media metrics are unrelated to the effect.

  8. In vitro studies of copper release from powder particles in synthetic biological media

    International Nuclear Information System (INIS)

    Midander, Klara; Wallinder, Inger Odnevall; Leygraf, Christofer

    2007-01-01

    The aim of this paper is to provide quantitative data on copper release from powder particles of different copper materials, including artificial copper patina, Cu 2 O and metallic Cu, when exposed to different synthetic biological media to simulate an inhalation scenario and/or skin contact. Generated data may contribute in risk assessment of potential health effects following exposure to and handling of various copper materials. All tests were performed in vitro to determine total copper concentrations, release rates of total copper, and to elucidate its time-dependence. The copper release process was interpreted in terms of specific surface area, surface morphology-, and composition. All powder materials show a time-dependent release process with total copper release rates less than 3 μg/cm 2 per hour at steady state conditions, for all media investigated. The importance of using relevant test media when simulating different interstitial lung conditions and difficulties encountered when comparing powder particles of essentially different properties are thoroughly discussed. - Copper release rates from particles are essential to assess potential health aspects

  9. 40 CFR 1065.690 - Buoyancy correction for PM sample media.

    Science.gov (United States)

    2010-07-01

    ... mass, use a sample media density of 920 kg/m3. (3) For PTFE membrane (film) media with an integral... media. 1065.690 Section 1065.690 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Buoyancy correction for PM sample media. (a) General. Correct PM sample media for their buoyancy in air if...

  10. Sample preparation in alkaline media

    International Nuclear Information System (INIS)

    Nobrega, Joaquim A.; Santos, Mirian C.; Sousa, Rafael A. de; Cadore, Solange; Barnes, Ramon M.; Tatro, Mark

    2006-01-01

    The use of tetramethylammonium hydroxide, tertiary amines and strongly alkaline reagents for sample treatment involving extraction and digestion procedures is discussed in this review. The preparation of slurries is also discussed. Based on literature data, alkaline media offer a good alternative for sample preparation involving an appreciable group of analytes in different types of samples. These reagents are also successfully employed in tailored speciation procedures wherein there is a critical dependence on maintenance of chemical forms. The effects of these reagents on measurements performed using spectroanalytical techniques are discussed. Several undesirable effects on transport and atomization processes necessitate use of the method of standard additions to obtain accurate results. It is also evident that alkaline media can improve the performance of techniques such as inductively coupled plasma mass spectrometry and accessories, such as autosamplers coupled to graphite furnace atomic absorption spectrometers

  11. Influence of MRI contrast media on histamine release from mast cells.

    Science.gov (United States)

    Kun, Tomasz; Jakubowski, Lucjusz

    2012-07-01

    Mast cells, owing to diversity of secreted mediators, play a crucial role in the regulation of inflammatory response. Together with basophils, mast cells constitute a central pathogenetic element of anaphylactic (IgE-dependent) and anaphylactoid (IgE-independent) reactions. In severe cases, generalized degranulation of mast cells may cause symptoms of anaphylactic shock. The influence of the classical, iodine-based contrast media on mastocyte degranulation has been fully described. Our objective was to determine the influence of the gadolinium-based MRI contrast media on histamine release from mast cells and to compare the activity of ionic and non-ionic preparations of contrast media. To determine the intensity of mast cell degranulation, we used an experimental model based on mastocytes isolated from rat peritoneal fluid. Purified suspensions of mast cells were incubated with various concentrations of Gd-DTPA and Gd-DTPA-BMA, and solutions of PEG 600 which served as a non-toxic osmotic stimulus. The intensity of mast cell activation was presented as mean percentage of histamine released from cells after incubation. The obtained results demonstrate that both ionic and non-ionic preparations of the MRI contrast media are able to induce mast cell degranulation in vitro. It was also proved that the non-ionic MRI contrast media stimulate mast cells markedly more weakly than ionic contrast media at identical concentration. The aforementioned results may suggest a more profitable safety profile of the non-ionic contrast preparations. We may also conclude that triggering of mast cell degranulation after incubation with the solutions of MRI contrast media results from non-specific osmotic stimulation and direct toxicity of free ionic residues.

  12. Influence of MRI contrast media on histamine release from mast cells

    International Nuclear Information System (INIS)

    Kun, Tomasz; Jakubowski, Lucjusz

    2012-01-01

    Mast cells, owing to diversity of secreted mediators, play a crucial role in the regulation of inflammatory response. Together with basophils, mast cells constitute a central pathogenetic element of anaphylactic (IgE-dependent) and anaphylactoid (IgE-independent) reactions. In severe cases, generalized degranulation of mast cells may cause symptoms of anaphylactic shock. The influence of the classical, iodine-based contrast media on mastocyte degranulation has been fully described. Our objective was to determine the influence of the gadolinium-based MRI contrast media on histamine release from mast cells and to compare the activity of ionic and non-ionic preparations of contrast media. To determine the intensity of mast cell degranulation, we used an experimental model based on mastocytes isolated from rat peritoneal fluid. Purified suspensions of mast cells were incubated with various concentrations of Gd-DTPA and Gd-DTPA-BMA, and solutions of PEG 600 which served as a non-toxic osmotic stimulus. The intensity of mast cell activation was presented as mean percentage of histamine released from cells after incubation. The obtained results demonstrate that both ionic and non-ionic preparations of the MRI contrast media are able to induce mast cell degranulation in vitro. It was also proved that the non-ionic MRI contrast media stimulate mast cells markedly more weakly than ionic contrast media at identical concentration. The aforementioned results may suggest a more profitable safety profile of the non-ionic contrast preparations. We may also conclude that triggering of mast cell degranulation after incubation with the solutions of MRI contrast media results from non-specific osmotic stimulation and direct toxicity of free ionic residues

  13. A radiolabel-release microwell assay for proteolytic enzymes present in cell culture media

    International Nuclear Information System (INIS)

    Rucklidge, G.J.; Milne, G.

    1990-01-01

    A modified method for the measurement of proteolytic enzyme activity in cell culture-conditioned media has been developed. Using the release of 3H-labeled peptides from 3H-labeled gelatin the method is performed in microwell plates. The substrate is insolubilized and attached to the wells by glutaraldehyde treatment, thus eliminating the need for a precipitation step at the end of the assay. The assay is sensitive, reproducible, and convenient for small sample volumes. The effect of different protease inhibitors on activity can be assessed rapidly allowing an early characterization of the enzyme. It can also be adapted to microplate spectrophotometric analysis by staining residual substrate with Coomassie blue

  14. Media Exposure: How Models Simplify Sampling

    DEFF Research Database (Denmark)

    Mortensen, Peter Stendahl

    1998-01-01

    In media planning, the distribution of exposures to more ad spots in more media (print, TV, radio) is crucial to the evaluation of the campaign. If such information should be sampled, it would only be possible in expensive panel-studies (eg TV-meter panels). Alternatively, the distribution...... of exposures may be modelled statistically, using the Beta distribution combined with the Binomial Distribution. Examples are given....

  15. Tracking the release of IPCC AR5 on Twitter: Users, comments, and sources following the release of the Working Group I Summary for Policymakers.

    Science.gov (United States)

    Newman, Todd P

    2017-10-01

    Using the immediate release of the Working Group 1 Summary for Policymakers of the Intergovernmental Panel on Climate Change Fifth Assessment Report as a case study, this article seeks to describe what type of actors were most active during the summary release, the substance of the most propagated tweets during the summary release, and the media sources that attracted the most attention during the summary release. The results from the study suggest that non-elite actors, such as individual bloggers and concerned citizens, accounted for the majority of the most propagated tweets in the sample. This study also finds that the majority of the most propagated tweets in the sample focused on public understanding of the report. Finally, while mainstream media sources were the most frequently discussed media sources, a number of new media and science news and information sources compete for audience attention.

  16. The effect of loading solution and dissolution media on release of Diclofenac from ion exchange resins

    Directory of Open Access Journals (Sweden)

    "Atyabi F

    2002-07-01

    Full Text Available Drugs can be loaded on ion exchange resins in order to control their release. Loading of diclofenac sodium on the resin beads not only sustain its release but also reduce its gastrointestinal mucosal injury. In this study the effect of loading solution and concentration of diclofenac in loading solution on total amount of drug loaded on the resin beads (Amberlite IRA-900 and the release characteristic of drug in different media were examined. Results showed that diclofenac resin complex did not release their drug content in simulated gastric fluid but released it in simulated intestinal fluid independent of exposure time in acidic conditions. The effect of a number of parameters such as ionic strength and pH on the release characteristic of drug - resin complexes were also examined. Results showed that although ionic strength is an important factor, drug release is more affected by the pH of the media. NO ABSTRACT

  17. Release of Si from Silicon, a Ferrosilicon (FeSi) Alloy and a Synthetic Silicate Mineral in Simulated Biological Media

    Science.gov (United States)

    Herting, Gunilla; Jiang, Tao; Sjöstedt, Carin; Odnevall Wallinder, Inger

    2014-01-01

    Unique quantitative bioaccessibility data has been generated, and the influence of surface/material and test media characteristics on the elemental release process were assessed for silicon containing materials in specific synthetic body fluids at certain time periods at a fixed loading. The metal release test protocol, elaborated by the KTH team, has previously been used for classification, ranking, and screening of different alloys and metals. Time resolved elemental release of Si, Fe and Al from particles, sized less than 50 µm, of two grades of metallurgical silicon (high purity silicon, SiHG, low purity silicon, SiLG), an alloy (ferrosilicon, FeSi) and a mineral (aluminium silicate, AlSi) has been investigated in synthetic body fluids of varying pH, composition and complexation capacity, simple models of for example dermal contact and digestion scenarios. Individual methods for analysis of released Si (as silicic acid, Si(OH)4) in synthetic body fluids using GF-AAS were developed for each fluid including optimisation of solution pH and graphite furnace parameters. The release of Si from the two metallurgical silicon grades was strongly dependent on both pH and media composition with the highest release in pH neutral media. No similar effect was observed for the FeSi alloy or the aluminium silicate mineral. Surface adsorption of phosphate and lactic acid were believed to hinder the release of Si whereas the presence of citric acid enhanced the release as a result of surface complexation. An increased presence of Al and Fe in the material (low purity metalloid, alloy or mineral) resulted in a reduced release of Si in pH neutral media. The release of Si was enhanced for all materials with Al at their outermost surface in acetic media. PMID:25225879

  18. Release of Si from silicon, a ferrosilicon (FeSi alloy and a synthetic silicate mineral in simulated biological media.

    Directory of Open Access Journals (Sweden)

    Gunilla Herting

    Full Text Available Unique quantitative bioaccessibility data has been generated, and the influence of surface/material and test media characteristics on the elemental release process were assessed for silicon containing materials in specific synthetic body fluids at certain time periods at a fixed loading. The metal release test protocol, elaborated by the KTH team, has previously been used for classification, ranking, and screening of different alloys and metals. Time resolved elemental release of Si, Fe and Al from particles, sized less than 50 µm, of two grades of metallurgical silicon (high purity silicon, SiHG, low purity silicon, SiLG, an alloy (ferrosilicon, FeSi and a mineral (aluminium silicate, AlSi has been investigated in synthetic body fluids of varying pH, composition and complexation capacity, simple models of for example dermal contact and digestion scenarios. Individual methods for analysis of released Si (as silicic acid, Si(OH4 in synthetic body fluids using GF-AAS were developed for each fluid including optimisation of solution pH and graphite furnace parameters. The release of Si from the two metallurgical silicon grades was strongly dependent on both pH and media composition with the highest release in pH neutral media. No similar effect was observed for the FeSi alloy or the aluminium silicate mineral. Surface adsorption of phosphate and lactic acid were believed to hinder the release of Si whereas the presence of citric acid enhanced the release as a result of surface complexation. An increased presence of Al and Fe in the material (low purity metalloid, alloy or mineral resulted in a reduced release of Si in pH neutral media. The release of Si was enhanced for all materials with Al at their outermost surface in acetic media.

  19. A novel dissolution media for testing drug release from a nanostructured polysaccharide-based colon specific drug delivery system: an approach to alternative colon media.

    Science.gov (United States)

    Kotla, Niranjan G; Singh, Sima; Maddiboyina, Balaji; Sunnapu, Omprakash; Webster, Thomas J

    2016-01-01

    The aim of this study was to develop a novel microbially triggered and animal-sparing dissolution method for testing of nanorough polysaccharide-based micron granules for colonic drug delivery. In this method, probiotic cultures of bacteria present in the colonic region were prepared and added to the dissolution media and compared with the performance of conventional dissolution methodologies (such as media with rat cecal and human fecal media). In this study, the predominant species (such as Bacteroides, Bifidobacterium, Lactobacillus species, Eubacterium and Streptococcus) were cultured in 12% w/v skimmed milk powder and 5% w/v grade "A" honey. Approximately 10(10)-10(11) colony forming units m/L of probiotic culture was added to the dissolution media to test the drug release of polysaccharide-based formulations. A USP dissolution apparatus I/II using a gradient pH dissolution method was used to evaluate drug release from formulations meant for colonic drug delivery. Drug release of guar gum/Eudragit FS30D coated 5-fluorouracil granules was assessed under gastric and small intestine conditions within a simulated colonic environment involving fermentation testing with the probiotic culture. The results with the probiotic system were comparable to those obtained from the rat cecal and human fecal-based fermentation model, thereby suggesting that a probiotic dissolution method can be successfully applied for drug release testing of any polysaccharide-based oral formulation meant for colonic delivery. As such, this study significantly adds to the nanostructured biomaterials' community by elucidating an easier assay for colonic drug delivery.

  20. Statistical sampling method for releasing decontaminated vehicles

    International Nuclear Information System (INIS)

    Lively, J.W.; Ware, J.A.

    1996-01-01

    Earth moving vehicles (e.g., dump trucks, belly dumps) commonly haul radiologically contaminated materials from a site being remediated to a disposal site. Traditionally, each vehicle must be surveyed before being released. The logistical difficulties of implementing the traditional approach on a large scale demand that an alternative be devised. A statistical method (MIL-STD-105E, open-quotes Sampling Procedures and Tables for Inspection by Attributesclose quotes) for assessing product quality from a continuous process was adapted to the vehicle decontamination process. This method produced a sampling scheme that automatically compensates and accommodates fluctuating batch sizes and changing conditions without the need to modify or rectify the sampling scheme in the field. Vehicles are randomly selected (sampled) upon completion of the decontamination process to be surveyed for residual radioactive surface contamination. The frequency of sampling is based on the expected number of vehicles passing through the decontamination process in a given period and the confidence level desired. This process has been successfully used for 1 year at the former uranium mill site in Monticello, Utah (a CERCLA regulated clean-up site). The method forces improvement in the quality of the decontamination process and results in a lower likelihood that vehicles exceeding the surface contamination standards are offered for survey. Implementation of this statistical sampling method on Monticello Projects has resulted in more efficient processing of vehicles through decontamination and radiological release, saved hundreds of hours of processing time, provided a high level of confidence that release limits are met, and improved the radiological cleanliness of vehicles leaving the controlled site

  1. Apparatus for sampling hazardous media

    International Nuclear Information System (INIS)

    Gardner, J.F.; Showalter, T.W.

    1984-01-01

    An apparatus for sampling a hazardous medium, such as radioactive or chemical waste, selectively collects a predetermined quantity of the medium in a recess of an end-over-end rotatable valving member. This collected quantity is deposited in a receiving receptacle located in a cavity while the receiving receptacle is in a sealed relationship with a recess to prevent dusting of the sampled media outside the receiving receptacle. The receiving receptacle is removably fitted within a vehicle body which is, in turn, slidably movable upon a track within a transport tube. The receiving receptacle is transported in the vehicle body from its sample receiving position within a container for the hazardous medium to a sample retrieval position outside the medium container. The receiving receptacle may then be removed from the vehicle body, capped and taken to a laboratory for chemical analysis. (author)

  2. News/Press Releases

    Data.gov (United States)

    Office of Personnel Management — A press release, news release, media release, press statement is written communication directed at members of the news media for the purpose of announcing programs...

  3. A novel dissolution media for testing drug release from a nanostructured polysaccharide-based colon specific drug delivery system: an approach to alternative colon media

    Directory of Open Access Journals (Sweden)

    Kotla NG

    2016-03-01

    Full Text Available Niranjan G Kotla,1,2 Sima Singh,1,3 Balaji Maddiboyina,4 Omprakash Sunnapu,2 Thomas J Webster5,6 1School of Pharmaceutical Sciences, Lovely Professional University, Punjab, India; 2Technologies for the Advancement of Science, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, Karnataka, India; 3Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India; 4Department of Pharmaceutics, Vishwabharathi College of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India; 5Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 6Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi Arabia Abstract: The aim of this study was to develop a novel microbially triggered and animal-sparing dissolution method for testing of nanorough polysaccharide-based micron granules for colonic drug delivery. In this method, probiotic cultures of bacteria present in the colonic region were prepared and added to the dissolution media and compared with the performance of conventional dissolution methodologies (such as media with rat cecal and human fecal media. In this study, the predominant species (such as Bacteroides, Bifidobacterium, Lactobacillus species, Eubacterium and Streptococcus were cultured in 12% w/v skimmed milk powder and 5% w/v grade “A” honey. Approximately 1010–1011 colony forming units m/L of probiotic culture was added to the dissolution media to test the drug release of polysaccharide-based formulations. A USP dissolution apparatus I/II using a gradient pH dissolution method was used to evaluate drug release from formulations meant for colonic drug delivery. Drug release of guar gum/Eudragit FS30D coated 5-fluorouracil granules was assessed under gastric and small intestine conditions within a simulated colonic environment involving fermentation testing with the probiotic culture. The results with the probiotic system were

  4. Effect of Otitis Media with Effusion on Comodulation Masking Release in Children.

    Science.gov (United States)

    Hall, Joseph W.; Grose, John H.

    1994-01-01

    This study investigated comodulation masking release (CMR) in 42 children (ages 5 to 10) with a history of otitis media with effusion (OME) and 19 control children with no history of ear disease. Results indicated that monotic CMRs were reduced in children with hearing loss due to OME and these CMRs remained abnormally small for several months.…

  5. A simple homogeneous model for regular and irregular metallic wire media samples

    Science.gov (United States)

    Kosulnikov, S. Y.; Mirmoosa, M. S.; Simovski, C. R.

    2018-02-01

    To simplify the solution of electromagnetic problems with wire media samples, it is reasonable to treat them as the samples of a homogeneous material without spatial dispersion. The account of spatial dispersion implies additional boundary conditions and makes the solution of boundary problems difficult especially if the sample is not an infinitely extended layer. Moreover, for a novel type of wire media - arrays of randomly tilted wires - a spatially dispersive model has not been developed. Here, we introduce a simplistic heuristic model of wire media samples shaped as bricks. Our model covers WM of both regularly and irregularly stretched wires.

  6. Two media method for linear attenuation coefficient determination of irregular soil samples

    International Nuclear Information System (INIS)

    Vici, Carlos Henrique Georges

    2004-01-01

    In several situations of nuclear applications, the knowledge of gamma-ray linear attenuation coefficient for irregular samples is necessary, such as in soil physics and geology. This work presents the validation of a methodology for the determination of the linear attenuation coefficient (μ) of irregular shape samples, in such a way that it is not necessary to know the thickness of the considered sample. With this methodology irregular soil samples (undeformed field samples) from Londrina region, north of Parana were studied. It was employed the two media method for the μ determination. It consists of the μ determination through the measurement of a gamma-ray beam attenuation by the sample sequentially immersed in two different media, with known and appropriately chosen attenuation coefficients. For comparison, the theoretical value of μ was calculated by the product of the mass attenuation coefficient, obtained by the WinXcom code, and the measured value of the density sample. This software employs the chemical composition of the samples and supplies a table of the mass attenuation coefficients versus the photon energy. To verify the validity of the two media method, compared with the simple gamma ray transmission method, regular pome stone samples were used. With these results for the attenuation coefficients and their respective deviations, it was possible to compare the two methods. In this way we concluded that the two media method is a good tool for the determination of the linear attenuation coefficient of irregular materials, particularly in the study of soils samples. (author)

  7. SOCIAL MEDIA

    Science.gov (United States)

    RESPONSIBILITY CENTCOM COALITION MEDIA SOCIAL MEDIA NEWS ARTICLES PRESS RELEASES IMAGERY VIDEOS TRANSCRIPTS VISITORS AND PERSONNEL FAMILY CENTER FAMILY READINESS CENTCOM WEBMAIL SOCIAL MEDIA SECURITY ACCOUNTABILITY HomeMEDIASOCIAL MEDIA Social Media CENTCOM'S ENGLISH SOCIAL MEDIA ACCOUNTS There are many U.S. military commands

  8. Problematic Social Media Use: Results from a Large-Scale Nationally Representative Adolescent Sample.

    Science.gov (United States)

    Bányai, Fanni; Zsila, Ágnes; Király, Orsolya; Maraz, Aniko; Elekes, Zsuzsanna; Griffiths, Mark D; Andreassen, Cecilie Schou; Demetrovics, Zsolt

    2017-01-01

    Despite social media use being one of the most popular activities among adolescents, prevalence estimates among teenage samples of social media (problematic) use are lacking in the field. The present study surveyed a nationally representative Hungarian sample comprising 5,961 adolescents as part of the European School Survey Project on Alcohol and Other Drugs (ESPAD). Using the Bergen Social Media Addiction Scale (BSMAS) and based on latent profile analysis, 4.5% of the adolescents belonged to the at-risk group, and reported low self-esteem, high level of depression symptoms, and elevated social media use. Results also demonstrated that BSMAS has appropriate psychometric properties. It is concluded that adolescents at-risk of problematic social media use should be targeted by school-based prevention and intervention programs.

  9. Problematic Social Media Use: Results from a Large-Scale Nationally Representative Adolescent Sample.

    Directory of Open Access Journals (Sweden)

    Fanni Bányai

    Full Text Available Despite social media use being one of the most popular activities among adolescents, prevalence estimates among teenage samples of social media (problematic use are lacking in the field. The present study surveyed a nationally representative Hungarian sample comprising 5,961 adolescents as part of the European School Survey Project on Alcohol and Other Drugs (ESPAD. Using the Bergen Social Media Addiction Scale (BSMAS and based on latent profile analysis, 4.5% of the adolescents belonged to the at-risk group, and reported low self-esteem, high level of depression symptoms, and elevated social media use. Results also demonstrated that BSMAS has appropriate psychometric properties. It is concluded that adolescents at-risk of problematic social media use should be targeted by school-based prevention and intervention programs.

  10. Recovery efficiencies for Burkholderia thailandensis from various aerosol sampling media

    Directory of Open Access Journals (Sweden)

    Paul eDabisch

    2012-06-01

    Full Text Available Burkholderia thailandensis is used in the laboratory as a surrogate of the more virulent B. pseudomallei. Since inhalation is believed to be a natural route of infection for B. pseudomallei, many animal studies with B. pseudomallei and B. thailandensis utilize the inhalation route of exposure. The aim of the present study was to quantify the recovery efficiency of culturable B. thailandensis from several common aerosol sampling devices to ensure that collected microorganisms could be reliably recovered post-collection. The sampling devices tested included 25-mm gelatin filters, 25-mm stainless steel disks used in Mercer cascade impactors, and two types of glass impingers. The results demonstrate that while several processing methods tested resulted in significantly lower physical recovery efficiencies than other methods, it was possible to obtain culturable recovery efficiencies for B. thailandensis and physical recovery efficiencies for 1 μm fluorescent spheres of at least 0.95 from all of the sampling media tested given an appropriate sample processing procedure. The results of the present study also demonstrated that the bubbling action of liquid media in all-glass impingers (AGIs can result in physical loss of material from the collection medium, although additional studies are needed to verify the exact mechanisms involved. Overall, the results of this study demonstrate that the collection mechanism as well as the post-collection processing method can significantly affect the recovery from and retention of culturable microorganisms in sampling media, potentially affecting the calculated airborne concentration and any subsequent estimations of risk or dose derived from such data.

  11. SOCIAL MEDIA SECURITY

    Science.gov (United States)

    RESPONSIBILITY CENTCOM COALITION MEDIA SOCIAL MEDIA NEWS ARTICLES PRESS RELEASES IMAGERY VIDEOS TRANSCRIPTS VISITORS AND PERSONNEL FAMILY CENTER FAMILY READINESS CENTCOM WEBMAIL SOCIAL MEDIA SECURITY ACCOUNTABILITY HomeVISITORS AND PERSONNELSOCIAL MEDIA SECURITY FAQ on Security for Social Media Due to the widespread use of

  12. The Influence of High Drug Loading in Xanthan Tablets and Media with Different Physiological pH and Ionic Strength on Swelling and Release.

    Science.gov (United States)

    Mikac, Urša; Sepe, Ana; Baumgartner, Saša; Kristl, Julijana

    2016-03-07

    The formation of a gel coat around xanthan (Xan) tablets, empty or loaded with pentoxifylline (PF), and its release in media differing in pH and ionic strength by NMR, MR imaging, and two release methods were studied. The T1 and T2 NMR relaxation times in gels depend predominantly on Xan concentration; the presence of PF has negligible influence on them. It is interesting that the matrix swelling is primarily regulated by Xan despite high drug loading (25%, 50%). The gastric pH and high ionic strength of the media do not influence the position of the penetration and swelling fronts but do affect the erosion front and gel thickness. The different release profiles obtained in mixing and nonmixing in vitro methods are the consequence of matrix hydration level and erosion at the surface. In water and in diluted acid medium with low ionic strength, the main release mechanism is erosion, whereas in other media (pH 1.2, μ ≥ 0.20 M), anomalous transport dominates as was found out by fitting of measured data with theoretical model. Besides the in vitro investigation that mimics gastric conditions, mathematical modeling makes the product development more successful.

  13. The effect of pH and ionic strength of dissolution media on in-vitro release of two model drugs of different solubilities from HPMC matrices.

    Science.gov (United States)

    Asare-Addo, Kofi; Conway, Barbara R; Larhrib, Hassan; Levina, Marina; Rajabi-Siahboomi, Ali R; Tetteh, John; Boateng, Joshua; Nokhodchi, Ali

    2013-11-01

    The evaluation of the effects of different media ionic strengths and pH on the release of hydrochlorothiazide, a poorly soluble drug, and diltiazem hydrochloride, a cationic and soluble drug, from a gel forming hydrophilic polymeric matrix was the objective of this study. The drug to polymer ratio of formulated tablets was 4:1. Hydrochlorothiazide or diltiazem HCl extended release (ER) matrices containing hypromellose (hydroxypropyl methylcellulose (HPMC)) were evaluated in media with a pH range of 1.2-7.5, using an automated USP type III, Bio-Dis dissolution apparatus. The ionic strength of the media was varied over a range of 0-0.4M to simulate the gastrointestinal fed and fasted states and various physiological pH conditions. Sodium chloride was used for ionic regulation due to its ability to salt out polymers in the midrange of the lyotropic series. The results showed that the ionic strength had a profound effect on the drug release from the diltiazem HCl K100LV matrices. The K4M, K15M and K100M tablets however withstood the effects of media ionic strength and showed a decrease in drug release to occur with an increase in ionic strength. For example, drug release after the 1h mark for the K100M matrices in water was 36%. Drug release in pH 1.2 after 1h was 30%. An increase of the pH 1.2 ionic strength to 0.4M saw a reduction of drug release to 26%. This was the general trend for the K4M and K15M matrices as well. The similarity factor f2 was calculated using drug release in water as a reference. Despite similarity occurring for all the diltiazem HCl matrices in the pH 1.2 media (f2=64-72), increases of ionic strength at 0.2M and 0.4M brought about dissimilarity. The hydrochlorothiazide tablet matrices showed similarity at all the ionic strength tested for all polymers (f2=56-81). The values of f2 however reduced with increasing ionic strengths. DSC hydration results explained the hydrochlorothiazide release from their HPMC matrices. There was an increase in

  14. Trolling new media: violent extremist groups recruiting through social media

    OpenAIRE

    Chang, Mark D.

    2015-01-01

    Approved for public release; distribution is unlimited With the advent and subsequent growth of several new media technologies, violent extremist groups have incorporated social media into recruiting strategies. How are violent extremist groups using social media for recruiting? This thesis explores several new media technologies—websites, blogs, social media, mobile phones, and online gaming—to determine if violent extremist groups rely on social media for recruiting. By comparing the com...

  15. Attitudes of a Sample of English, Maltese and German Teachers towards Media Education

    Science.gov (United States)

    Lauri, M. A.; Borg, J.; Gunnel, T.; Gillum, R.

    2010-01-01

    Media education forms part of the National Minimum Curriculum of England, Malta and Germany. Teacher training courses differ greatly in how teachers are prepared to teach media education. In this paper we shall investigate the attitudes of a sample of teachers trained in England, Malta and in Germany towards their perceived importance of media…

  16. Canada on the Move: an intensive media analysis from inception to reception.

    Science.gov (United States)

    Faulkner, Guy; Finlay, Sara-Jane

    2006-01-01

    Research evaluating mediated physical activity campaigns uses an unsophisticated conceptualization of the media and would benefit from the application of a media studies approach. The purpose of this article is to report on the application of this type of analysis to the Canada on the Move media campaign. Through interviews and document analysis, the press release surrounding Canada on the Move was examined at four levels: inception, production, transmission and reception. Analytic strategies of thematic and textual analysis were conducted. The press release was well received by journalists and editors and was successfully transmitted as inferred from national and local television coverage, although there was no national print pickup. Canada on the Move was perceived by sampled audience members as a useful and interesting strategy to encourage walking. A holistic approach to media analysis reveals the complex and frequently messy process of this mediated communication process. Implications for future media disseminations of Canada on the Move are discussed.

  17. Air exposure and sample storage time influence on hydrogen release from tungsten

    Energy Technology Data Exchange (ETDEWEB)

    Moshkunov, K.A., E-mail: moshkunov@gmail.co [National Research Nuclear University ' MEPhI' , Kashirskoe sh. 31, 115409 Moscow (Russian Federation); Schmid, K.; Mayer, M. [Max-Planck-Institut fuer Plasmaphysik, EURATOM Association, Boltzmannstrasse 2, D-85748 Garching (Germany); Kurnaev, V.A.; Gasparyan, Yu.M. [National Research Nuclear University ' MEPhI' , Kashirskoe sh. 31, 115409 Moscow (Russian Federation)

    2010-09-30

    In investigations of hydrogen retention in first wall components the influence of the conditions of the implanted target storage prior to analysis and the storage time is often neglected. Therefore we have performed a dedicated set of experiments. The release of hydrogen from samples exposed to ambient air after irradiation was compared to samples kept in vacuum. For air exposed samples significant amounts of HDO and D{sub 2}O are detected during TDS. Additional experiments have shown that heavy water is formed by recombination of releasing D and H atoms with O on the W surface. This water formation can alter hydrogen retention results significantly, in particular - for low retention cases. In addition to the influence of ambient air exposure also the influence of storage time in vacuum was investigated. After implantation at 300 K the samples were stored in vacuum for up to 1 week during which the retained amount decreased significantly. The subsequently measured TDS spectra showed that D was lost from both the high and low energy peaks during storage at ambient temperature of {approx}300 K. An attempt to simulate this release from both peaks during room temperature storage by TMAP 7 calculations showed that this effect cannot be explained by conventional diffusion/trapping models.

  18. Air exposure and sample storage time influence on hydrogen release from tungsten

    International Nuclear Information System (INIS)

    Moshkunov, K.A.; Schmid, K.; Mayer, M.; Kurnaev, V.A.; Gasparyan, Yu.M.

    2010-01-01

    In investigations of hydrogen retention in first wall components the influence of the conditions of the implanted target storage prior to analysis and the storage time is often neglected. Therefore we have performed a dedicated set of experiments. The release of hydrogen from samples exposed to ambient air after irradiation was compared to samples kept in vacuum. For air exposed samples significant amounts of HDO and D 2 O are detected during TDS. Additional experiments have shown that heavy water is formed by recombination of releasing D and H atoms with O on the W surface. This water formation can alter hydrogen retention results significantly, in particular - for low retention cases. In addition to the influence of ambient air exposure also the influence of storage time in vacuum was investigated. After implantation at 300 K the samples were stored in vacuum for up to 1 week during which the retained amount decreased significantly. The subsequently measured TDS spectra showed that D was lost from both the high and low energy peaks during storage at ambient temperature of ∼300 K. An attempt to simulate this release from both peaks during room temperature storage by TMAP 7 calculations showed that this effect cannot be explained by conventional diffusion/trapping models.

  19. Air exposure and sample storage time influence on hydrogen release from tungsten

    Science.gov (United States)

    Moshkunov, K. A.; Schmid, K.; Mayer, M.; Kurnaev, V. A.; Gasparyan, Yu. M.

    2010-09-01

    In investigations of hydrogen retention in first wall components the influence of the conditions of the implanted target storage prior to analysis and the storage time is often neglected. Therefore we have performed a dedicated set of experiments. The release of hydrogen from samples exposed to ambient air after irradiation was compared to samples kept in vacuum. For air exposed samples significant amounts of HDO and D 2O are detected during TDS. Additional experiments have shown that heavy water is formed by recombination of releasing D and H atoms with O on the W surface. This water formation can alter hydrogen retention results significantly, in particular - for low retention cases. In addition to the influence of ambient air exposure also the influence of storage time in vacuum was investigated. After implantation at 300 K the samples were stored in vacuum for up to 1 week during which the retained amount decreased significantly. The subsequently measured TDS spectra showed that D was lost from both the high and low energy peaks during storage at ambient temperature of ˜300 K. An attempt to simulate this release from both peaks during room temperature storage by TMAP 7 calculations showed that this effect cannot be explained by conventional diffusion/trapping models.

  20. Abnormal gel flotation caused by contrast media during adrenal vein sampling.

    Science.gov (United States)

    Lima-Oliveira, Gabriel; Lippi, Giuseppe; Salvagno, Gian Luca; Gelati, Matteo; Bassi, Antonella; Contro, Alberto; Pizzolo, Francesca; Guidi, Gian Cesare

    2016-10-15

    During adrenal venous sampling (AVS) procedure, radiologists administer a contrast agent via the catheter to visualize the proper catheter position. A patient with primary aldosteronism diagnostic-hypothesis was admitted for AVS. A venogram was performed to
confirm the catheter's position with 2mL of Iopamidol 300 mg/mL. Samples were collected with syringe connected to a hydrophilic coated catheter by low-pressure aspiration from each of the four collection sites: inferior vena cava in the suprarenal portion, inferior vena cava in the infrarenal portion, left adrenal vein, and right adrenal vein; then immediately transferred from syringe to tubes with gel separator. All tubes were centrifuged at 1200 x g for 10 minutes. At the end of centrifugation process, primary blood tubes containing blood from inferior vena cava and left adrenal vein exhibited the standard gel separator barrier, while tubes from right adrenal vein showed abnormal flotation of gel separator. The radiologist confirmed the usage of 2.6 mL instead of 2.0 mL of Iopamidol 300 mg/mL. This iodinated contrast media, with 1.33 g/cm 3 of density, was used close to the right adrenal vein due to some difficulty to access it. The abnormal flotation of gel separator in samples taken from right adrenal vein can be explained by the usage of the iodinated
contrast media. We suggest using plain-tubes (without gel separator) for AVS in order to avoid preanalytical nonconformities. Moreover, a blood volume equivalent to twice the catheter extension should be discarded to eliminate residual contrast media before collection of samples for laboratory assays.

  1. Antibiotic content of selective culture media for isolation of Capnocytophaga species from oral polymicrobial samples.

    Science.gov (United States)

    Ehrmann, E; Jolivet-Gougeon, A; Bonnaure-Mallet, M; Fosse, T

    2013-10-01

    In oral microbiome, because of the abundance of commensal competitive flora, selective media with antibiotics are necessary for the recovery of fastidious Capnocytophaga species. The performances of six culture media (blood agar, chocolate blood agar, VCAT medium, CAPE medium, bacitracin chocolate blood agar and VK medium) were compared with literature data concerning five other media (FAA, LB, TSBV, CapR and TBBP media). To understand variable growth on selective media, the MICs of each antimicrobial agent contained in this different media (colistin, kanamycin, trimethoprim, trimethoprim-sulfamethoxazole, vancomycin, aztreonam and bacitracin) were determined for all Capnocytophaga species. Overall, VCAT medium (Columbia, 10% cooked horse blood, polyvitaminic supplement, 3·75 mg l(-1) of colistin, 1·5 mg l(-1) of trimethoprim, 1 mg l(-1) of vancomycin and 0·5 mg l(-1) of amphotericin B, Oxoid, France) was the more efficient selective medium, with regard to the detection of Capnocytophaga species from oral samples (P culture, a simple blood agar allowed the growth of all Capnocytophaga species. Nonetheless, in oral samples, because of the abundance of commensal competitive flora, selective media with antibiotics are necessary for the recovery of Capnocytophaga species. The demonstrated superiority of VCAT medium made its use essential for the optimal detection of this bacterial genus. This work showed that extreme caution should be exercised when reporting the isolation of Capnocytophaga species from oral polymicrobial samples, because the culture medium is a determining factor. © 2013 The Society for Applied Microbiology.

  2. Seasonal and temporal variation in release of antibiotics in hospital wastewater: estimation using continuous and grab sampling.

    Science.gov (United States)

    Diwan, Vishal; Stålsby Lundborg, Cecilia; Tamhankar, Ashok J

    2013-01-01

    The presence of antibiotics in the environment and their subsequent impact on resistance development has raised concerns globally. Hospitals are a major source of antibiotics released into the environment. To reduce these residues, research to improve knowledge of the dynamics of antibiotic release from hospitals is essential. Therefore, we undertook a study to estimate seasonal and temporal variation in antibiotic release from two hospitals in India over a period of two years. For this, 6 sampling sessions of 24 hours each were conducted in the three prominent seasons of India, at all wastewater outlets of the two hospitals, using continuous and grab sampling methods. An in-house wastewater sampler was designed for continuous sampling. Eight antibiotics from four major antibiotic groups were selected for the study. To understand the temporal pattern of antibiotic release, each of the 24-hour sessions were divided in three sub-sampling sessions of 8 hours each. Solid phase extraction followed by liquid chromatography/tandem mass spectrometry (LC-MS/MS) was used to determine the antibiotic residues. Six of the eight antibiotics studied were detected in the wastewater samples. Both continuous and grab sampling methods indicated that the highest quantities of fluoroquinolones were released in winter followed by the rainy season and the summer. No temporal pattern in antibiotic release was detected. In general, in a common timeframe, continuous sampling showed less concentration of antibiotics in wastewater as compared to grab sampling. It is suggested that continuous sampling should be the method of choice as grab sampling gives erroneous results, it being indicative of the quantities of antibiotics present in wastewater only at the time of sampling. Based on our studies, calculations indicate that from hospitals in India, an estimated 89, 1 and 25 ng/L/day of fluroquinolones, metronidazole and sulfamethoxazole respectively, might be getting released into the

  3. CLASSICAL MEDIA RELATIONS AND NEW MEDIA RELATIONS IN SPORT

    Directory of Open Access Journals (Sweden)

    Alexandru Lucian MIHAI

    2014-06-01

    Full Text Available Media relations in sport mean maintenance of networks and positive relationships with people in the media to obtain positive media exposure for a sport product (informal and formal information sessions with media representatives. Because of the pervasive influence the media has on marketing success, sport marketers must make concerted efforts to create a positive relationship between their sport event and the media. They may accomplish this by providing the media with press releases, having news conferences, having media-day events (in which the media are invited to interact with the players, coaches, and administrators, providing media guides for the respective sport events and so on. Each of these activities promotes active involvement from the media, which will subsequently contribute to relationship building with the community.

  4. Air modelling as an alternative to sampling for low-level radioactive airborne releases

    International Nuclear Information System (INIS)

    Morgenstern, M.Y.; Hueske, K.

    1995-01-01

    This paper describes our efforts to assess the effect of airborne releases at one DOE laboratory using air modelling based on historical data. Among the facilities affected by these developments is Los Alamos National Laboratory (LANL) in New Mexico. RCRA, as amended by the Hazardous and Solid Waste Amendments (HSWA) in 1984, requires all facilities which involve the treatment, storage, and disposal of hazardous waste obtain a RCRA/HSWA waste facility permit. LANL complied with CEARP by initiating a process of identifying potential release sites associated with LANL operations prior to filing a RCRA/HSWA permit application. In the process of preparing the RCRA/HSWA waste facility permit application to the U.S. Environmental Protection Agency (EPA), a total of 603 Solid Waste Management Units (SWMUs) were identified as part of the requirements of the HSWA Module VIH permit requirements. The HSWA Module VIII permit requires LANL to determine whether there have been any releases of hazardous waste or hazardous constituents from SWMUs at the facility dating from the 1940's by performing a RCRA Facility Investigation to address known or suspected releases from specified SWMUs to affected media (i.e. soil, groundwater, surface water, and air). Among the most troublesome of the potential releases sites are those associated with airborne radioactive releases. In order to assess health risks associated with radioactive contaminants in a manner consistent with exposure standards currently in place, the DOE and LANL have established Screening Action Levels (SALs) for radioactive soil contamination. The SALs for each radionuclide in soil are derived from calculations based on a residential scenario in which individuals are exposed to contaminated soil via inhalation and ingestion as well as external exposure to gamma emitters in the soil. The applicable SALs are shown

  5. Determinants of social media usage among a sample of rural South African youth

    Directory of Open Access Journals (Sweden)

    Herring Shava

    2018-03-01

    Full Text Available Background: Youths have been found to utilise and adopt information communication technology (ICT faster than any other population cohort. This has been aided by the advent of social media, especially Facebook and Instagram as platforms of choice. Calls have been made for more research (especially in rural communities on the usage of ICT platforms such as social media among the youth as a basis for interventions that not only allow for better communication but also for learning.   Objectives: The research investigated the relationship between knowledge sharing, habit and obligation in relation to social media usage among a sample of rural South African youth.   Method: This study is descriptive by design. Primary data were collected from 447 youths domiciled within a rural community in the Eastern Cape Province of South Africa using a self-administered questionnaire. The respondents to the study were all social media users. A combination of descriptive statistics and Pearson’s correlation analysis was used to make meaning of the data.   Results: The study found a significant positive correlation to exist in all three independent variables (knowledge sharing, habit and obligation with the dependent variable (social media usage concerning Facebook usage among the sample of South African rural youth.   Conclusion: Based on the findings of the research, recommendations and implications with regard to theory and practice are made.

  6. Measurements of linear attenuation coefficients of irregular shaped samples by two media method

    International Nuclear Information System (INIS)

    Singh, Sukhpal; Kumar, Ashok; Thind, Kulwant Singh; Mudahar, Gurmel S.

    2008-01-01

    The linear attenuation coefficient values of regular and irregular shaped flyash materials have been measured without knowing the thickness of a sample using a new technique namely 'two media method'. These values have also been measured with a standard gamma ray transmission method and obtained theoretically with winXCOM computer code. From the comparison it is reported that the two media method has given accurate results of attenuation coefficients of flyash materials

  7. Awareness of media-based antitobacco messages among a community sample of LGBT individuals.

    Science.gov (United States)

    Matthews, Alicia K; Balsam, Kimberly; Hotton, Anna; Kuhns, Lisa; Li, Chien-Ching; Bowen, Deborah J

    2014-11-01

    Study objectives were to measure awareness of general antitobacco messages in LGBT-focused and general media outlets among LGBT (lesbian, gay, bisexual, and transgender) individuals and to examine associations between sociodemographic characteristics and awareness levels. Data were based on cross-sectional survey data from a racially diverse sample of participants (N = 726). Participants were primarily male (69.3%), with smaller percentages of female (21.8%) and transgender (8.9%). The median age was 31 years. A higher proportion of participants reported awareness of antitobacco messages in general media outlets compared to LGBT-specific media outlets. Awareness of antitobacco messages in general media was positively associated with current smoking and negatively associated with female gender and Latino ethnicity. Awareness of antitobacco messages in LGBT media was positively associated with younger age, current smoking, frequent reading of LGBT newspapers or magazines, and frequent attendance at LGBT bars and negatively associated with Latino ethnicity. Despite frequent readership, awareness of antitobacco messages in LGBT newspapers/magazines was quite low. We speculate that low awareness is related to the absence of antitobacco messages in LGBT-related media. LGBT-specific media outlets provide an important opportunity for future antitobacco campaigns. © 2014 Society for Public Health Education.

  8. Device for sampling radioactive and aggressive liquid and vaporous media

    International Nuclear Information System (INIS)

    Przibram, E.; Halm, G.

    1974-01-01

    The equipment enables the taking of samples even of radioactive media from a main pipeline in the through-flow in a closed system. A tap device is attached to the main pipeline which branches into two parts. The one branch contains the actual tap which is closed to both sides with snap closure coupling. It is only used for taking samples. The other branch bridges the tap position as a bypass so that a representative sample is always available. Both branches join up again and lead back to the main pipeline. The sampling can be used in a nuclear power plant for the determination of O 2 , CI, SiO 2 , and Cu. A millilitre collecting cylinder and a millipore filtration device can be connected to the tap for liquid sampling and solid analysis, respectively. The system can be extended to several tap positions. Permanent measuring equipment is attached to the bypass pipe to control the sample liquid. (DG) [de

  9. The SAMPLE experience: The development of a rich media online mathematics learning environment

    OpenAIRE

    Chang, Jen

    2006-01-01

    This report documents the development of Sample Architecture for Mathematically Productive Learning Experiences (SAMPLE), a rich media, online, mathematics learning environment created to meet the needs of middle school educators. It explores some of the current pedagogical challenges in mathematics education, and their amplified impacts when coupled with under-prepared teachers, a decidedly wide-spread phenomenon. The SAMPLE publishing experience is discussed in terms of its instructional de...

  10. Nuclear power plants and the environment. Water samplings and releases

    International Nuclear Information System (INIS)

    Hartmann, Philippe; Bordet, Francois; Chevalier, Christian; Colin, Jean-Luc; Khalanski, Michel

    2013-01-01

    This voluminous and illustrated guide aims at giving detailed information on the nature of waters used by nuclear power plants and of releases, on how these samplings and controls are performed, on the associated risks for the environment and public health, and on how public is informed. After a general overview of these issues, a chapter addresses the protection of nature and biodiversity and the actions performed by EDF in this respect. The next chapter deals with public information. The next chapters discuss the water needs of a nuclear power plant, effluent releases and their impacts. Two chapters are dedicated to the monitoring and control of the environment, and to the various techniques of environmental metrology. Legal and regulatory aspects are then presented

  11. DEA Multi-Media Drug Library

    Science.gov (United States)

    ... Releases Speeches and Testimony Major Operations Multi-Media Library Micrograms Legislative & Legal Resources Events Social Media Directory ... Envío de información confidencial Press Room » Multi-Media Library IMAGE GALLERY Drug Photos Amphetamines/Stimulants K2/Spice ...

  12. Influence of enrichment and isolation media on the detection of Campylobacter spp. in naturally contaminated chicken samples.

    Science.gov (United States)

    Repérant, E; Laisney, M J; Nagard, B; Quesne, S; Rouxel, S; Le Gall, F; Chemaly, M; Denis, M

    2016-09-01

    Investigating Campylobacter epidemiology requires adequate technique and media to ensure optimal culturing and accurate detection and isolation of Campylobacter strains. In the present study, we investigated the performances of three enrichment durations in Bolton broth (0, 24 and 48h) and compared four isolation media (mCCDA, Karmali, Butzler no. 2 and CampyFood agar (CFA)) for the detection of Campylobacter positive samples and the identification of Campylobacter species, from naturally contaminated broiler chicken samples (caeca, neck skin from carcasses, and skin from thighs). We compared our local results to those we obtained with samples from a European survey (caeca and neck skin) and a national survey (neck skin, thigh skin, and breast). Direct plating favored the detection of positive samples highly contaminated by Campylobacter (caeca and neck skin from carcasses) whatever the media. A longer enrichment reduced the rates of Campylobacter recovery except when using Butzler no. 2, more particularly for neck skin which background microflora was less important than in caeca. As a matter of fact, enrichment allowed a higher detection rate of positive samples with low Campylobacter contamination levels (breast, thigh skin), this detection being enhanced when using Butzler no. 2. When comparing the 3 other selective media, CFA was the 2nd most efficient media prior to mCCDA and Karmali. Interestingly, enrichment promoted the growth of Campylobacter coli but this promotion was least with Butzler no. 2 agar. Our study has confirmed the need to adapt the method to the types of samples for improving the detection of Campylobacter and that the method may affect the prevalence of the species. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Acrosin release and acrosin activity during incubation in capacitating media using fresh and frozen-thawed dog sperm

    Directory of Open Access Journals (Sweden)

    Mónica de los Reyes

    2011-01-01

    Full Text Available We evaluated the effect of time and temperature on acrosin release from the acrosomal cap and the activity of this enzyme during in vitro capacitation in fresh and frozen/thawed dog sperm. Sperm-rich fractions of six ejaculates from three dogs were processed as fresh and frozen samples. Each sperm sample was incubated in canine capacitation medium (CCM for 0, 1, 2 and 3 h at 20°C and at 37°C. After incubation, the samples were assessed by the indirect immunofluorescent staining technique. The probability of having unlabeled sperm (PUS, indicating acrosin loss, was modelled by a binomial distribution using logistic regression. There was a linear relationship between PUS and time at both temperatures (p<0.001; however, a major percentage of unlabeled sperm was observed in frozen/thawed samples soon after incubation, indicating that the release of acrosin was affected by capacitation time, mainly in frozen samples. Temperature influenced acrosin release only in cryopreserved sperm (p<0.05. Acrosin activity was measured by digestion halos on slides coated with gelatin-substrate film during each time period; a significant increase in the number of large halos was observed in fresh samples throughout the experiment, whereas frozen/thawed sperm showed a decreased rate of halo diameters during culture. Thus, there appears to differences between fresh and frozen dog sperm in terms of acrosin release and the level of acrosin activity in the course of in vitro capacitation.

  14. Development of a code to simulate dispersion of atmospheric released tritium gas in the environmental media and to evaluate doses. TRIDOSE

    International Nuclear Information System (INIS)

    Murata, Mikio; Noguchi, Hiroshi; Yokoyama, Sumi

    2000-11-01

    A computer code (TRIDOSE) was developed to assess the environmental impact of atmospheric released tritium gas (T 2 ) from nuclear fusion related facilities. The TRIDOSE simulates dispersion of T 2 and resultant HTO in the atmosphere, land, plant, water and foods in the environment, and evaluates contamination concentrations in the media and exposure doses. A part of the mathematical models in TRIDOSE were verified by comparison of the calculation with the results of the short range (400 m) dispersion experiment of HT gas performed in Canada postulating a short-time (30 minutes) accidental release. (author)

  15. How Many Samples and How Many Culture Media To Diagnose a Prosthetic Joint Infection: a Clinical and Microbiological Prospective Multicenter Study.

    Science.gov (United States)

    Bémer, Pascale; Léger, Julie; Tandé, Didier; Plouzeau, Chloé; Valentin, Anne Sophie; Jolivet-Gougeon, Anne; Lemarié, Carole; Kempf, Marie; Héry-Arnaud, Geneviève; Bret, Laurent; Juvin, Marie Emmanuelle; Giraudeau, Bruno; Corvec, Stéphane; Burucoa, Christophe

    2016-02-01

    Although numerous perioperative samples and culture media are required to diagnose prosthetic joint infection (PJI), their exact number and types have not yet been definitely determined with a high level of proof. We conducted a prospective multicenter study to determine the minimal number of samples and culture media required for accurate diagnosis of PJI. Over a 2-year period, consecutive patients with clinical signs suggesting PJI were included, with five perioperative samples per patient. The bacteriological and PJI diagnosis criteria were assessed using a random selection of two, three, or four samples and compared with those obtained using the recommended five samples (references guidelines). The results obtained with two or three culture media were then compared with those obtained with five culture media for both criteria. The times-to-positivity of the different culture media were calculated. PJI was confirmed in 215/264 suspected cases, with a bacteriological criterion in 192 (89%). The PJI was monomicrobial (85%) or polymicrobial (15%). Percentages of agreement of 98.1% and 99.7%, respectively, for the bacteriological criterion and confirmed PJI diagnosis were obtained when four perioperative samples were considered. The highest percentages of agreement were obtained with the association of three culture media, a blood culture bottle, a chocolate agar plate, and Schaedler broth, incubated for 5, 7, and 14 days, respectively. This new procedure leads to significant cost saving. Our prospective multicenter study showed that four samples seeded on three culture media are sufficient for diagnosing PJI. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  16. 28 CFR 552.33 - Media.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Media. 552.33 Section 552.33 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT CUSTODY Hostage Situation Management § 552.33 Media. The Warden shall assign staff to handle all news releases and news media inquiries...

  17. Development of a code to simulate dispersion of atmospheric released tritium gas in the environmental media and to evaluate doses. TRIDOSE

    Energy Technology Data Exchange (ETDEWEB)

    Murata, Mikio [Nuclear Engineering Co., Ltd., Hitachi, Ibaraki (Japan); Noguchi, Hiroshi; Yokoyama, Sumi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2000-11-01

    A computer code (TRIDOSE) was developed to assess the environmental impact of atmospheric released tritium gas (T{sub 2}) from nuclear fusion related facilities. The TRIDOSE simulates dispersion of T{sub 2} and resultant HTO in the atmosphere, land, plant, water and foods in the environment, and evaluates contamination concentrations in the media and exposure doses. A part of the mathematical models in TRIDOSE were verified by comparison of the calculation with the results of the short range (400 m) dispersion experiment of HT gas performed in Canada postulating a short-time (30 minutes) accidental release. (author)

  18. A proposal on alternative sampling-based modeling method of spherical particles in stochastic media for Monte Carlo simulation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Song Hyun; Lee, Jae Yong; KIm, Do Hyun; Kim, Jong Kyung [Dept. of Nuclear Engineering, Hanyang University, Seoul (Korea, Republic of); Noh, Jae Man [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-08-15

    Chord length sampling method in Monte Carlo simulations is a method used to model spherical particles with random sampling technique in a stochastic media. It has received attention due to the high calculation efficiency as well as user convenience; however, a technical issue regarding boundary effect has been noted. In this study, after analyzing the distribution characteristics of spherical particles using an explicit method, an alternative chord length sampling method is proposed. In addition, for modeling in finite media, a correction method of the boundary effect is proposed. Using the proposed method, sample probability distributions and relative errors were estimated and compared with those calculated by the explicit method. The results show that the reconstruction ability and modeling accuracy of the particle probability distribution with the proposed method were considerably high. Also, from the local packing fraction results, the proposed method can successfully solve the boundary effect problem. It is expected that the proposed method can contribute to the increasing of the modeling accuracy in stochastic media.

  19. A proposal on alternative sampling-based modeling method of spherical particles in stochastic media for Monte Carlo simulation

    International Nuclear Information System (INIS)

    Kim, Song Hyun; Lee, Jae Yong; KIm, Do Hyun; Kim, Jong Kyung; Noh, Jae Man

    2015-01-01

    Chord length sampling method in Monte Carlo simulations is a method used to model spherical particles with random sampling technique in a stochastic media. It has received attention due to the high calculation efficiency as well as user convenience; however, a technical issue regarding boundary effect has been noted. In this study, after analyzing the distribution characteristics of spherical particles using an explicit method, an alternative chord length sampling method is proposed. In addition, for modeling in finite media, a correction method of the boundary effect is proposed. Using the proposed method, sample probability distributions and relative errors were estimated and compared with those calculated by the explicit method. The results show that the reconstruction ability and modeling accuracy of the particle probability distribution with the proposed method were considerably high. Also, from the local packing fraction results, the proposed method can successfully solve the boundary effect problem. It is expected that the proposed method can contribute to the increasing of the modeling accuracy in stochastic media

  20. Bounds on the sample complexity for private learning and private data release

    Energy Technology Data Exchange (ETDEWEB)

    Kasiviswanathan, Shiva [Los Alamos National Laboratory; Beime, Amos [BEN-GURION UNIV.; Nissim, Kobbi [BEN-GURION UNIV.

    2009-01-01

    Learning is a task that generalizes many of the analyses that are applied to collections of data, and in particular, collections of sensitive individual information. Hence, it is natural to ask what can be learned while preserving individual privacy. [Kasiviswanathan, Lee, Nissim, Raskhodnikova, and Smith; FOCS 2008] initiated such a discussion. They formalized the notion of private learning, as a combination of PAC learning and differential privacy, and investigated what concept classes can be learned privately. Somewhat surprisingly, they showed that, ignoring time complexity, every PAC learning task could be performed privately with polynomially many samples, and in many natural cases this could even be done in polynomial time. While these results seem to equate non-private and private learning, there is still a significant gap: the sample complexity of (non-private) PAC learning is crisply characterized in terms of the VC-dimension of the concept class, whereas this relationship is lost in the constructions of private learners, which exhibit, generally, a higher sample complexity. Looking into this gap, we examine several private learning tasks and give tight bounds on their sample complexity. In particular, we show strong separations between sample complexities of proper and improper private learners (such separation does not exist for non-private learners), and between sample complexities of efficient and inefficient proper private learners. Our results show that VC-dimension is not the right measure for characterizing the sample complexity of proper private learning. We also examine the task of private data release (as initiated by [Blum, Ligett, and Roth; STOC 2008]), and give new lower bounds on the sample complexity. Our results show that the logarithmic dependence on size of the instance space is essential for private data release.

  1. Media Coverage, Journal Press Releases and Editorials Associated with Randomized and Observational Studies in High-Impact Medical Journals: A Cohort Study.

    Directory of Open Access Journals (Sweden)

    Michael T M Wang

    Full Text Available Publication of clinical research findings in prominent journals influences health beliefs and medical practice, in part by engendering news coverage. Randomized controlled trials (RCTs should be most influential in guiding clinical practice. We determined whether study design of clinical research published in high-impact journals influences media coverage.We compared the incidence and amount of media coverage of RCTs with that of observational studies published in the top 7 medical journals between 1 January 2013 and 31 March 2013. We specifically assessed media coverage of the most rigorous RCTs, those with >1000 participants that reported 'hard' outcomes. There was no difference between RCTs and observational studies in coverage by major newspapers or news agencies, or in total number of news stories generated (all P>0.63. Large RCTs reporting 'hard' outcomes did not generate more news coverage than small RCTs that reported surrogate outcomes and observational studies (all P>0.32. RCTs were more likely than observational studies to attract a journal editorial (70% vs 46%, P = 0.003, but less likely to be the subject of a journal press release (17% vs 50%, P0.99, nor were they more likely to be the subject of a journal press release (14% vs 38%, P = 0.14.The design of clinical studies whose results are published in high-impact medical journals is not associated with the likelihood or amount of ensuing news coverage.

  2. Accelerated in vitro release testing method for naltrexone loaded PLGA microspheres.

    Science.gov (United States)

    Andhariya, Janki V; Choi, Stephanie; Wang, Yan; Zou, Yuan; Burgess, Diane J; Shen, Jie

    2017-03-30

    The objective of the present study was to develop a discriminatory and reproducible accelerated release testing method for naltrexone loaded parenteral polymeric microspheres. The commercially available naltrexone microsphere product (Vivitrol ® ) was used as the testing formulation in the in vitro release method development, and both sample-and-separate and USP apparatus 4 methods were investigated. Following an in vitro drug stability study, frequent media replacement and addition of anti-oxidant in the release medium were used to prevent degradation of naltrexone during release testing at "real-time" (37°C) and "accelerated" (45°C), respectively. The USP apparatus 4 method was more reproducible than the sample-and-separate method. In addition, the accelerated release profile obtained using USP apparatus 4 had a shortened release duration (within seven days), and good correlation with the "real-time" release profile. Lastly, the discriminatory ability of the developed accelerated release method was assessed using compositionally equivalent naltrexone microspheres with different release characteristics. The developed accelerated USP apparatus 4 release method was able to detect differences in the release characteristics of the prepared naltrexone microspheres. Moreover, a linear correlation was observed between the "real-time" and accelerated release profiles of all the formulations investigated, suggesting that the release mechanism(s) may be similar under both conditions. These results indicate that the developed accelerated USP apparatus 4 method has the potential to be an appropriate fast quality control tool for long-acting naltrexone PLGA microspheres. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Influence of Biochar on Deposition and Release of Clay Colloids in Saturated Porous Media.

    Science.gov (United States)

    Haque, Muhammad Emdadul; Shen, Chongyang; Li, Tiantian; Chu, Haoxue; Wang, Hong; Li, Zhen; Huang, Yuanfang

    2017-11-01

    Although the potential application of biochar in soil remediation has been recognized, the effect of biochar on the transport of clay colloids, and accordingly the fate of colloid-associated contaminants, is unclear to date. This study conducted saturated column experiments to systematically examine transport of clay colloids in biochar-amended sand porous media in different electrolytes at different ionic strengths. The obtained breakthrough curves were simulated by the convection-diffusion equation, which included a first-order deposition and release terms. The deposition mechanisms were interpreted by calculating Derjaguin-Landau-Verwey-Overbeek interaction energies. A linear relationship between the simulated deposition rate or the attachment efficiency and the fraction of biochar was observed ( ≥ 0.91), indicating more favorable deposition in biochar than in sand. The interaction energy calculations show that the greater deposition in biochar occurs because the half-tube-like cavities on the biochar surfaces favor deposition in secondary minima and the nanoscale physical and chemical heterogeneities on the biochar surfaces increase deposition in primary minima. The deposited clay colloids in NaCl can be released by reduction of ionic strength, whereas the presence of a bivalent cation (Ca) results in irreversible deposition due to the formation of cation bridging between the colloids and biochar surfaces. The deposition and release of clay colloids on or from biochar surfaces not only change their mobilizations in the soil but also influence the efficiency of the biochar for removal of pollutants. Therefore, the influence of biochar on clay colloid transport must be considered before application of the biochar in soil remediation. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  4. Depictions of mental illness in print media: a prospective national sample.

    Science.gov (United States)

    Coverdale, John; Nairn, Raymond; Claasen, Donna

    2002-10-01

    Because there are no published reports of depictions of mental illness in print media based on national samples, we set out to prospectively collect and analyse a near complete New Zealand sample of print media. A commercial clipping bureau was contracted to provide cuttings of all items with any mental health or illness aspect over a four week period. These items were analysed for potentially positive and negative depictions and how mental illness was represented within each item. An independent search for additional newspaper items concerning one prominently featured topic indicated that the rate of identification of relevant stories was at least 91%. The collection consisted of six hundred print items which were most commonly news or editorial pieces (n = 562, 93.7%). Negative depictions predominated, with dangerousness to others (n = 368, 61.3%) and criminality (n = 284, 47.3%) being the most common. Positive depictions, including human rights themes, leadership and educational accomplishments occurred in 27% (n = 164) of all items. Generic mental illness terminology without reference to specific diagnostic categories was present in 47% of all items (n = 284). Negative depictions that predominate confirm the stereotypic understanding of mental illness that is stigmatizing. These findings underscore the challenge facing us as mental health professionals attempting to change attitudes towards mental disorders when the stereotypes are so regularly reinforced.

  5. Generating news media interest in tobacco control; challenges in an advanced policy environment.

    Science.gov (United States)

    MacKenzie, Ross; Chapman, Simon

    2012-08-01

    To determine the efficacy of using media releases for tobacco control advocacy in Australia's advanced policy environment. Between February and August 2010, news releases that summarised either newly published but unpublicized research findings, or local developments in tobacco control, were sent to NSW media outlets. Reports arising from the releases were tracked using commercial services Media Monitors and Factiva, as well as Google and Google News. Other tobacco control related news items during the same period were also tracked and recorded. Twenty-one news releases generated 93 news items across all news media, with a quarter of these related to a story of porcine haemoglobin in cigarette filters. By comparison, 'live' policy issues (especially plain packaging and a significant tobacco tax increase) covered in this period attracted 1,033 news stories in the Australian media. Press releases describing recently published, but underpublicized research were issued in weeks where no major competing tobacco control news occurred. Results of this project indicate that in environments with advanced tobacco policy, media opportunities related to tobacco control advocacy are limited, as many objectives have been achieved. The media can still play a key advocacy role in such environments, and advocates need to be particularly vigilant for opportunities that do arise. The paper also highlights the increasingly important role of internet-based media, including opportunities presented by social media for tobacco control.

  6. The release of elements from dental casting alloy into cell-culture medium and artificial saliva.

    Science.gov (United States)

    Can, Gülşen; Akpınar, Gül; Aydın, Ahmet

    2007-04-01

    The biocompatibility of dental casting alloys is a critical issue because these alloys are in long-term intimate contact with oral tissues. Since the biocompatibility of alloys is not completely known; the release of elements from the alloys has been studied. The aim of this study was to compare the elemental release from dental casting alloy during exposure to artificial saliva and cell-culture medium. Twenty specimens made from Ni-Cr alloy were provided in the form of 5 mm diameter discs, 2 mm in thickness with a 7 mm stem attached to one face to facilitate handling. Ten of twenty samples were polished separately using a conventional technique. The remaining ten samples were left sandblasted with 50 mum Al(2)0(3). Ten samples (5 polished, 5 sandblasted) were separately placed into cell-culture wells with Dulbecco's Modified Eagle's Medium. The other ten samples were placed separately into cell-culture wells with artificial saliva. The samples were subjected in contact with these medium for 30 days. These medium were collected every 7 days. The cell-culture medium and artificial saliva without alloy samples were subjected to elemental analyses as a control. At the end of the exposure time, Atomic Absorption Spectrometry (AAS) was used to determine the release of elements from the alloys into all collected medium. Statistical analyses were assessed with two-way ANOVA. In general, the elemental release occurred with in all medium. The elemental releases of sandblasted alloys were higher than polished alloys. Artificial saliva was found to cause more release from the samples. In both media, Ni released from polished and sandblasted alloys were higher than Cr and Mo. The results suggest that the release of elements from the alloys might have correlated with the environments and the surface of dental alloy.

  7. 28 CFR 540.65 - Release of information.

    Science.gov (United States)

    2010-07-01

    ... 540.65 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT CONTACT WITH PERSONS IN THE COMMUNITY Contact With News Media § 540.65 Release of information. (a) The... media. Examples are deaths, inside escapes, and institution emergencies. (b) The Warden shall provide...

  8. Media Use and Source Trust among Muslims in Seven Countries: Results of a Large Random Sample Survey

    Directory of Open Access Journals (Sweden)

    Steven R. Corman

    2013-12-01

    Full Text Available Despite the perceived importance of media in the spread of and resistance against Islamist extremism, little is known about how Muslims use different kinds of media to get information about religious issues, and what sources they trust when doing so. This paper reports the results of a large, random sample survey among Muslims in seven countries Southeast Asia, West Africa and Western Europe, which helps fill this gap. Results show a diverse set of profiles of media use and source trust that differ by country, with overall low trust in mediated sources of information. Based on these findings, we conclude that mass media is still the most common source of religious information for Muslims, but that trust in mediated information is low overall. This suggests that media are probably best used to persuade opinion leaders, who will then carry anti-extremist messages through more personal means.

  9. Comparison of three media for transport and storage of the samples collected for detection of avian influenza virus.

    Science.gov (United States)

    Zhang, Xiao-Chun; Liu, Shuo; Hou, Guang-Yu; Zhuang, Qing-Ye; Wang, Kai-Cheng; Jiang, Wen-Ming; Wang, Su-Chun; Li, Jin-Ping; Yu, Jian-Min; Du, Xiang; Huang, Bao-Xu; Chen, Ji-Ming

    2015-09-15

    Detection of avian influenza viruses (AIVs) is important for diagnosis, surveillance and control of avian influenza which is of great economic and public health significance. Proper transport and storage of samples is critical for the detection when the samples cannot be detected immediately. As recommended by some international or national authoritative entities and some publications, phosphate buffered saline (PBS), PBS-glycerol and brain heart infusion broth (BHIB) are frequently used for transport and storage of the samples collected for detection of AIVs worldwide. In this study, we compared these three media for transport and storage of simulated and authentic swab and feces samples collected for detection of AIVs using virus isolation and reverse transcription-PCR. The results suggest that PBS-glycerol is superior to PBS and BHIB as the sample transport and storage media. The results also suggest that the samples collected for detection of AIVs should be detected as soon as possible because the virus concentration of the samples may decline rapidly during storage within days at 4 or -20°C. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Analysis of Institutional Press Releases and its Visibility in the Press

    Directory of Open Access Journals (Sweden)

    José Antonio Alcoceba-Hernando, Ph.D.

    2010-01-01

    Full Text Available The relationships between institutional communication and media communication influence the shaping of social representations of public issues. This research article analyses these relationships based on the case study of the external communication of a public institution, the press releases of Spain’s Youth Institute (Instituto de la Juventud, aka, Injuve, during three years and their repercussion in the press during the same period of time. The results obtained in this research allowed drawing conclusions on the types of communication production of the aforementioned institution and the news treatment of such pieces of information by the printed and digital media. The press releases and the news items were studied using quantitative media content analysis which focused, especially, in referential issues like the information treatment, the thematic analysis, youth representations in the case of the releases; and the visibility of the press releases in the making of news

  11. Colloid characterization and in situ release in shallow groundwater under different hydrogeology conditions.

    Science.gov (United States)

    Zhou, Jingjing; Liu, Dan; Zhang, Wenjing; Chen, Xuequn; Huan, Ying; Yu, Xipeng

    2017-06-01

    Changes to groundwater hydrodynamics and chemistry can lead to colloid release that can have a major impact on the groundwater environment. To analyze the effects of colloid release caused by artificial groundwater recharge, field and laboratory tests on colloid characterization and colloid release were conducted. The field tests were carried out at an artificial recharge test site in Shandong Province. In the field investigation, one recharge water sample and five groundwater samples were collected and filtered through three levels of ultrafiltration membranes, with pore sizes of 0.45 μm, 100 kDa, and 50 kDa. The field results indicated that the colloid mass concentrations in groundwater retained between membranes with pore sizes of 100 kDa-0.45 μm and 50 kDa-100 kDa were 19 and 62 mg/L, respectively. In recharge water, the colloid mass concentrations retained by 100-kDa-0.45-μm and 50-kDa-100-kDa membranes were 3 and 99 mg/L, respectively. Colloids detected on the ultrafiltration membranes were mainly inorganic between 100 kDa and 0.45 μm, and mainly organic between 50 and 100 kDa. Based on the field colloid investigation results, the organic colloid was chosen in the laboratory experiments to reveal its release behavior under different conditions. Porous media diameter, flux, ionic strength (IS), and ion valence were changed to determine their influences on organic colloid concentration outflow from undisturbed porous media. The experiment's results indicate that decreasing the diameter, and increasing the flux, ionic strength, and the number of divalent cations, can promote organic colloid release. The organic colloid release rate in the early stage was high and is thus likely to affect the quality of groundwater. The results provide a useful scientific basis for minimizing changes to hydrodynamic and hydrochemical conditions during artificial recharge, thus safeguarding groundwater quality.

  12. Using the media.

    Science.gov (United States)

    1994-01-01

    To use the mass media (newspaper, radio, and TV) to reach a large audience with information about AIDS, it is important to choose the media outlets carefully, since they use information that satisfies their audience in content and style. For example, radio, TV, or videos are best to reach illiterate groups. Ways to approach each sector of the written and electronic media include press releases, news conferences, information kits, and personal contacts. Letters to the editor and offers of submitting articles for publication are additional ways to approach newspapers. Audio- or videocassettes with interviews or images conveying HIV/AIDS prevention messages can be submitted to TV and radio stations. It is important to present the information attractively to gain the journalists' attention. News releases should include sources of information and a contact name. It is important to inform the mass media of successes revolving around AIDS prevention, emphasizing local successes. One should identify what media slots have the most influence. For example, a medical officer in Chiang Mai, Thailand, notes that popular disc jockeys have more influence than do government information broadcasts. It is best to promote facts that probably will increase support for AIDS prevention campaigns. If possible, groups should seek free space or air time for AIDS prevention messages. AIDS prevention messages should not use fear because it does not promote safer sexual behavior. Instead, they should link condom use with a sense of independence, responsibility, and being fashionable. Leaflets, posters, videotapes, slides, displays, slogans, audiocassettes, T-shirts, stickers, and other activities or products reinforce the effectiveness of media campaigns. Interviews with or feature articles and programs about people infected or affected by HIV/AIDS chip away at the belief that "AIDS could never happen to me."

  13. Nanoscale Coloristic Pigments: Upper Limits on Releases from Pigmented Plastic during Environmental Aging, In Food Contact, and by Leaching

    DEFF Research Database (Denmark)

    Neubauer, Nicole; Scifo, Lorette; Navratilova, Jana

    2017-01-01

    The life cycle of nanoscale pigments in plastics may cause environmental or human exposure by various release scenarios. We investigated spontaneous and induced release with mechanical stress during/after simulated sunlight and rain degradation of polyethylene (PE) with organic and inorganic...... pigments. Additionally, primary leaching in food contact and secondary leaching from nanocomposite fragments with an increased surface into environmental media was examined. Standardized protocols/methods for release sampling, detection, and characterization of release rate and form were applied......: Transformation of the bulk material was analyzed by Scanning Electron Microscopy (SEM), X-ray-tomography and Fourier-Transform Infrared spectroscopy (FTIR); releases were quantified by Inductively Coupled Plasma Mass Spectrometry (ICP-MS), single-particle-ICP-MS (sp-ICP-MS), Transmission Electron Microscopy (TEM...

  14. THE SLOAN DIGITAL SKY SURVEY QUASAR LENS SEARCH. IV. STATISTICAL LENS SAMPLE FROM THE FIFTH DATA RELEASE

    International Nuclear Information System (INIS)

    Inada, Naohisa; Oguri, Masamune; Shin, Min-Su; Kayo, Issha; Fukugita, Masataka; Strauss, Michael A.; Gott, J. Richard; Hennawi, Joseph F.; Morokuma, Tomoki; Becker, Robert H.; Gregg, Michael D.; White, Richard L.; Kochanek, Christopher S.; Chiu, Kuenley; Johnston, David E.; Clocchiatti, Alejandro; Richards, Gordon T.; Schneider, Donald P.; Frieman, Joshua A.

    2010-01-01

    We present the second report of our systematic search for strongly lensed quasars from the data of the Sloan Digital Sky Survey (SDSS). From extensive follow-up observations of 136 candidate objects, we find 36 lenses in the full sample of 77,429 spectroscopically confirmed quasars in the SDSS Data Release 5. We then define a complete sample of 19 lenses, including 11 from our previous search in the SDSS Data Release 3, from the sample of 36,287 quasars with i Λ = 0.84 +0.06 -0.08 (stat.) +0.09 -0.07 (syst.) assuming a flat universe, which is in good agreement with other cosmological observations. We also report the discoveries of seven binary quasars with separations ranging from 1.''1 to 16.''6, which are identified in the course of our lens survey. This study concludes the construction of our statistical lens sample in the full SDSS-I data set.

  15. Prescribing practices amid the OxyContin crisis: examining the effect of print media coverage on opioid prescribing among physicians.

    Science.gov (United States)

    Borwein, Alexandra; Kephart, George; Whelan, Emma; Asbridge, Mark

    2013-12-01

    The pain medication OxyContin (hereafter referred to as oxycodone extended release) has been the subject of sustained, and largely negative, media attention in recent years. We sought to determine whether media coverage of oxycodone extended release in North American newspapers has led to changes in prescribing of the drug in Nova Scotia, Canada. An interrupted time-series design examined the effect of media attention on physicians' monthly prescribing of opioids. The outcome measures were, for each physician, the monthly proportions of all opioids prescribed and the proportion of strong opioids prescribed that were for oxycodone extended release. The exposure of interest was media attention defined as the number of articles published each month in 27 North American newspapers. Variations in media effects by provider characteristics (specialty, prescribing volume, and region) were assessed. Within-provider changes in the prescribing of oxycodone extended release in Nova Scotia were observed, and they followed changes in media coverage. Oxycodone extended release prescribing rose steadily prior to receiving media attention. Following peak media attention in the United States, the prescribing of oxycodone extended release slowed. Likewise, following peak coverage in Canadian newspapers, the prescribing of oxycodone extended release declined. These patterns were observed across prescriber specialties and by prescriber volume, though the magnitude of change in prescribing varied. This study demonstrates that print media reporting of oxycodone extended release in North American newspapers, and its continued portrayal as a social problem, coincided with reductions in the prescribing of oxycodone extended release by physicians in Nova Scotia. Copyright © 2013 American Pain Society. Published by Elsevier Inc. All rights reserved.

  16. ASTP 15th Anniversary Clip-Media Release

    Science.gov (United States)

    1990-01-01

    This release is comprised of 5 separate clips, including the following: CL 762 Astronauts/Cosmonauts Visit to KSC and Walt Disney World; CL 739 ASTP Joint Crew Activities; CL 748 ASTP Astronauts/Cosmonauts Horlock Ranch Visit; CL 758 T-21 ASTP Training - US/USSR; and CL 743 ASTP Joint Crew Training in the Soviet Union.

  17. HIV/AIDS stigma among a sample of primarily African American and Latino men who have sex with men (MSM) social media users

    OpenAIRE

    Garett, Renee; Smith, Justin; Chiu, Jason; Young, Sean D.

    2016-01-01

    The recent increase in social media use allows these technologies to rapidly reach communities with higher HIV prevalence, such as African American and Latino men who have sex with men (MSM). However, no studies have looked at HIV/AIDS stigma among social media users from African American and Latino MSM communities, or the association between stigma and social media use among these groups. This study sought to assess the level of HIV/AIDS stigma among a sample of social media-using African Am...

  18. Researching media through practices: an ethnographic approach

    Directory of Open Access Journals (Sweden)

    Antoni Roig

    2009-05-01

    Full Text Available Anthropological and ethnographic research on media have been largely focused on analyzing reception of media products (television, radio, press and film and media consumption related to domestic appropriation of technologies (Rothenbuhler et al., 2005. There is also a wide body of research devoted to the study of the political dimension of alternative and indigenous media (Ginsburg, 2002. However, there has been a separation between media and internet studies, and between the analysis of media reception and practices of self-production, such as family photography or home video. Current digital media practices urge reexamination of self-produced content and media flows from a broader perspective that cuts across divisions between public and private, corporative media products and people's releases, home production and cultural industry, political activism and everyday life.

  19. Comparison of Sabouraud dextrose and Pagano-Levin agar media for detection and isolation of yeasts from oral samples.

    OpenAIRE

    Samaranayake, L P; MacFarlane, T W; Williamson, M I

    1987-01-01

    The sensitivities of Sabouraud dextrose agar and modified Pagano-Levin agar for the primary isolation of yeasts and the recovery of multiple yeast species from single clinical samples were compared by using oral-rinse samples. Although there was a highly significant positive correlation between the numbers of yeasts recovered from both media, modified Pagano-Levin agar was far superior in detecting multiple yeast species in a single sample. Of 150 oral samples containing yeasts, 23 (15.3%) co...

  20. Development of paradigm for the study of amino acid neurotransmitter release in human autopsy brain samples

    International Nuclear Information System (INIS)

    Kuo, K.-W.; Dodd, P.R.

    2001-01-01

    Full text: This study attempted to establish a release protocol to characterize both the vesicular and cytoplasmic components of amino acid transmitter release in human synaptosomes. Experiments with rat synaptosomes showed that, with depolarizing concentrations of K + ions, vesicular release could be successfully differentiated from cytoplasmic release for preloaded L-[ 3 H ]glutamate and [ 14 C ]GABA. However, human tissue studies did not give clear-cut results. Experiments were carried out to optimize the release paradigm as well as to improve the vesicular uptake of labeled transmitters. A 'pulse- chase' protocol, with an unlabelled D-aspartate chase, was performed in human tissue samples in order to enhance the L-[ 3 H ] glutamate release signal derived from exocytosis by removing the cytoplasmic pool of L-[ 3 H ] glutamate first. However, the results showed that total release was not enhanced effectively in comparison with the non-pulse-chase protocol. In brief, the pulse-chase protocol did not build up the vesicular pool of L-[ 3 H ]glutamate, though the cytoplasmic L- [ 3 H ] glutamate pool was effectively depressed by D-aspartate. Further studies applied 4- aminopyridine (4-AP) to trigger release, to circumvent the problem of the reversal of plasma membrane transporters caused by raised K + ion concentrations. The results showed that the application of 4-AP elicited the release of amino acid transmitters from rat synaptosomes, but failed to produce successful release signals in the human tissue experiments. Our findings suggest that the vesicular compartment may be impaired by freezing and affected by post-mortem delay (PMD). Rat studies showed that the freezing step had a major effect on Ca 2+-dependent release, as less L- [3 H ]glutamate and [ 14 C ]GABA were released from the frozen rat tissue preparations. Moreover, there was an indication of a decline in L-[ 3 H ]glutamate release with increasing PMD. Copyright (2001) Australian Neuroscience Society

  1. Protein alkylation, transcriptional responses and cytochrome c release during acrolein toxicity in A549 cells: influence of nucleophilic culture media constituents.

    Science.gov (United States)

    Thompson, Colin A; Burcham, Philip C

    2008-06-01

    Acrolein is a toxic combustion product that elicits apoptotic and/or necrotic cell death depending on the conditions under which exposure occurs. As a strong electrophile, side-reactions with nucleophilic media constituents seem likely to accompany study of its toxicity in vitro, but these reactions are poorly characterized. We have thus examined the effect of media composition on the toxicity of acrolein in A549 cells. Cells were exposed to acrolein in either Dulbecco's buffered saline (DBS) or F12 supplemented with various concentrations of fetal bovine serum. Cell viability was assessed using the MTT assay, while heme oxygenase-1 (HO-1) and cytoplasmic cytochrome c were measured as respective markers of transcriptional response and apoptosis. Protein damage was evaluated using the protein carbonyl assay. Compared to F12 media (with or without serum), maximal cell death as evaluated using the MTT assay, as well as adduction of intracellular proteins, occurred when cells were exposed to acrolein in DBS. In contrast, cytochrome c release was maximal in cells exposed to acrolein in serum-containing F12, conditions which inhibited protein modification and overt cell death. These findings highlight the need for careful attention to experimental conditions when conducting in vitro toxicological studies of reactive substances.

  2. Online ICPMS detection of the thermal release of fission products from nuclear fuel samples

    International Nuclear Information System (INIS)

    Guenther-Leopold, I.; Svedkauskaite-Le Gore, J.; Kivel, N.

    2009-01-01

    Full text: The release of volatile and semi-volatile fission products (like Cs, Tc, Mo etc.) from spent nuclear fuel by thermal and thermochemical treatment (oxidative or reductive conditions) as a head-end step for advanced reprocessing scenarios is studied in the Hot Laboratory of the Paul Scherrer Institut. For this purpose, a heated sampling cell online connected to an ICPMS (Element 2, Thermo Fisher Scientific) was designed and tested on simulated fuel samples up to 650 o C. The results of this study as well as technical perspectives for heating experiments up to 2000 o C will be presented. (author)

  3. Development and evaluation of accelerated drug release testing methods for a matrix-type intravaginal ring.

    Science.gov (United States)

    Externbrink, Anna; Eggenreich, Karin; Eder, Simone; Mohr, Stefan; Nickisch, Klaus; Klein, Sandra

    2017-01-01

    Accelerated drug release testing is a valuable quality control tool for long-acting non-oral extended release formulations. Currently, several intravaginal ring candidates designed for the long-term delivery of steroids or anti-infective drugs are being in the developing pipeline. The present article addresses the demand for accelerated drug release methods for these formulations. We describe the development and evaluation of accelerated release methods for a steroid releasing matrix-type intravaginal ring. The drug release properties of the formulation were evaluated under real-time and accelerated test conditions. Under real-time test conditions drug release from the intravaginal ring was strongly affected by the steroid solubility in the release medium. Under sufficient sink conditions that were provided in release media containing surfactants drug release was Fickian diffusion driven. Both temperature and hydro-organic dissolution media were successfully employed to accelerate drug release from the formulation. Drug release could be further increased by combining the temperature effect with the application of a hydro-organic release medium. The formulation continued to exhibit a diffusion controlled release kinetic under the investigated accelerated conditions. Moreover, the accelerated methods were able to differentiate between different prototypes of the intravaginal ring that exhibited different release profiles under real-time test conditions. Overall, the results of the present study indicate that both temperature and hydro-organic release media are valid parameters for accelerating drug release from the intravaginal ring. Variation of either a single or both parameters yielded release profiles that correlated well with real-time release. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. 14 CFR 1213.107 - Preventing unauthorized release of sensitive but unclassified (SBU) information/material to the...

    Science.gov (United States)

    2010-01-01

    .../material to the news media. (a) All NASA SBU information requires accountability and approval for release... sensitive but unclassified (SBU) information/material to the news media. 1213.107 Section 1213.107 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RELEASE OF INFORMATION TO NEWS AND...

  5. Parental bonds and body dissatisfaction in a clinical sample: The mediating roles of attachment anxiety and media internalization.

    Science.gov (United States)

    Grenon, Renee; Tasca, Giorgio A; Maxwell, Hilary; Balfour, Louise; Proulx, Genevieve; Bissada, Hany

    2016-12-01

    We evaluated an attachment theory model in which mother and father care were hypothesized to be indirectly related to body dissatisfaction mediated by attachment anxiety and media internalization. Participants were 232 women diagnosed with an eating disorder who completed a retrospective measure of parental bonds, and measures of attachment anxiety, media internalization, and body image. Mother care was negatively associated with body dissatisfaction, suggesting that recollection of mothers as less caring was directly related to poorer body image. Lower father care, was indirectly associated with greater body dissatisfaction mediated by higher attachment anxiety and higher media internalization. That is, women with an eating disorder who recollected fathers as less caring had higher attachment anxiety, which was related to greater internalizing of media-related thin ideals, that in turn was associated with poorer body image. Mothers and fathers may impact body dissatisfaction by differing mechanisms in clinical samples. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Novel Caffeic Acid Nanocarrier: Production, Characterization, and Release Modeling

    Directory of Open Access Journals (Sweden)

    Milad Fathi

    2013-01-01

    Full Text Available This paper deals with the development of novel nanocarriers using layer by layer carbohydrate coating of caffeic acid loaded solid lipid nanoparticles (SLNs to improve stability and colon delivery of the poorly water-soluble caffeic acid. Three biopolymers (chitosan, alginate, and pectin in different concentrations (0.1, 0.25, and 0.5% were electrostatically coated over the SLN surface. The size and zeta potential of produced nanocarriers were measured using photon correlation spectroscopy. Mathematical models (i.e., zero-order, first-order, Higuchi, Ritger-Peppas, reciprocal powered time, Weibull, and quadratic models were used to describe the release and kinetic modeling in gastrointestinal solution (GIS. Also, antioxidant activity of caffeic acid during the release in GIS was investigated using DPPH and reducing activity methods. The prepared treatments coated by alginate-chitosan as well as pectin-chitosan coated SLN at the concentration of 0.1% showed nanosized bead; the latter efficiently retarded the release of caffeic acid in gastric media up to 2.5 times higher than that of SLN. Zeta potential values of coated samples were found to significantly increase in comparison to SLN indicating the higher stability of produced nanocarriers. Antioxidant activity of caffeic acid after gastric release did not result in the same trend as observed for caffeic acid release from different treatments; however, in line with less caffeic acid release in the intestine solution by the effect of coating, lower antioxidant activity was determined at the end stage of the experiment.

  7. Social Media: New Spaces for Contention In Authoritarian Systems

    Science.gov (United States)

    2015-12-01

    restrictions and controls. Social media became the manner in which protesters used to mobilize as opposed to the traditional manner of word of mouth or...distribution is unlimited 12b. DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words ) What role has social media played in Bahraini political movements...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release; distribution is unlimited SOCIAL MEDIA : NEW

  8. Deposition and release kinetics of nano-TiO2 in saturated porous media: Effects of solution ionic strength and surfactants

    International Nuclear Information System (INIS)

    Godinez, Itzel G.; Darnault, Christophe J.G.; Khodadoust, Amid P.; Bogdan, Dorin

    2013-01-01

    The aggregation, transport and deposition kinetics (i.e. attachment and release) of TiO 2 nanoparticles (nano-TiO 2 ) were investigated as a function of ionic strength and the presence of anionic (sodium dodecylbenzene sulfonate, SDBS) and non-ionic (Triton X-100) surfactants in 100% critical micelle concentration (CMC). The electrolyte concentration of the suspensions dictated the kinetic stability of nano-TiO 2 thus influencing the transport and retention of the nanoaggregates in the saturated porous medium. With increasing ionic strength, the interaction between approaching nano-TiO 2 and nano-TiO 2 already deposited onto collectors surfaces seemed to be more favorable than the interaction between approaching nano-TiO 2 and bare collectors surfaces. The abrupt and gradual reduction in electrolyte concentration during the flushing cycles of the column experiments induced the release of previously deposited nano-TiO 2 suggesting attachment of nano-TiO 2 through secondary energy minimum. Highlights: ► This study focuses on aggregation, transport and deposition kinetics of nano-TiO 2 . ► Ionic strength and surfactants impact nano-TiO 2 transport in saturated porous media. ► Previously deposited nano-TiO 2 serve as preferential sites for subsequent deposition. ► Changes in solution chemistry cause nanodeposits to release a portion of nano-TiO 2 . -- Previously deposited nano-TiO 2 serve as preferential sites for subsequent deposition and changes in solution chemistry cause nanodeposits to release a portion of nano-TiO 2

  9. U.S. Air Force School of Aerospace Medicine Laboratory Sampling and Analysis Guide

    Science.gov (United States)

    2016-11-15

    Clay Sand Gravel Page | 63 DISTRIBUTION STATEMENT A. Approved for public release. Distribution is unlimited. Cleared, 88PA, # 2014-0577...solid/liquid, media will collect semi-liquid only. Not for high viscosity liquids. Dipper (or “pond sampler”) ASTM D5358 ASTM D5013 USEPA...decontamination may be difficult. Limited by length of sampler, small volume of sample collected, and viscosity of fluids. Page | 71

  10. Mobilization and Resistance through Social Media

    DEFF Research Database (Denmark)

    Vestergaard Jørgensen, Anne; Etter, Michael; Colleoni, Elanor

    Social media are widely considered as driving force for the institutionalization of CSR. It holds great potential for the empowerment of citizens, consumers, social movements or pressure groups. So far, this role of social media in the strategic communication of pressure groups is underexplored...... and associative frames (Guo & McCombs, 2011, Schultz et al., 2011) of the actors via semantic network analysis (1765 sentences in social media, 132 in press releases). The findings allow further evaluations of institutional, ethical and political conditions and reflections on the implications of “social media....... By analysing the use and content of social media of protest actors on the one hand and corporations on the other, the paper contributes to understanding the mechanisms, conditions and effects of social media based pressure on corporations. Drawing on social movement theory, discourse theory and neo...

  11. Fluoride release, recharge and flexural properties of polymethylmethacrylate containing fluoridated glass fillers.

    Science.gov (United States)

    Al-Bakri, I A; Swain, M V; Naoum, S J; Al-Omari, W M; Martin, E; Ellakwa, A

    2014-06-01

    The purpose of this study was to investigate the effect of fluoridated glass fillers on fluoride release, recharge and the flexural properties of modified polymethylmethacrylate (PMMA). Specimens of PMMA denture base material with various loading of fluoridated glass fillers (0%, 1%, 2.5%, 5% and 10% by weight) were prepared. Flexural properties were evaluated on rectangular specimens (n = 10) aged in deionized water after 24 hours, 1 and 3 months. Disc specimens (n = 10) were aged for 43 days in deionized water and lactic acid (pH 4.0) and fluoride release was measured at numerous intervals. After ageing, specimens were recharged and fluoride re-release was recorded at 1, 3 and 7 days after recharge. Samples containing 2.5%, 5% and 10% glass fillers showed significantly (p glass fillers specimens. All experimental specimens exhibited fluoride release in both media. The flexural strength of specimens decreased in proportion to the percentage filler inclusion with the modulus of elasticity values remaining within ISO Standard 1567. The modified PMMA with fluoridated glass fillers has the ability to release and re-release fluoride ion. Flexural strength decreased as glass filler uploading increased. © 2014 Australian Dental Association.

  12. Mercury speciation in environmental solid samples using thermal release technique with atomic absorption detection

    Energy Technology Data Exchange (ETDEWEB)

    Shuvaeva, Olga V. [Institute of Inorganic Chemistry, Academician Lavrent' ev Prospect 3, 630090 Novosbirsk (Russian Federation)], E-mail: olga@che.nsk.su; Gustaytis, Maria A.; Anoshin, Gennadii N. [Institute of Geology and Mineralogy, Siberian Branch of Russian Academy of Sciences, Koptyug Prospect 3, 630090 Novosibirsk (Russian Federation)

    2008-07-28

    A sensitive and very simple method for determination of mercury species in solid samples has been developed involving thermal release analysis in combination with atomic absorption (AAS) detection. The method allows determination of mercury(II) chloride, methylmercury and mercury sulfide at the level of 0.70, 0.35 and 0.20 ng with a reproducibility of the results of 14, 25 and 18%, respectively. The accuracy of the developed assay has been estimated using certified reference materials and by comparison of the results with those of an independent method. The method has been applied for Hg species determination in original samples of lake sediments and plankton.

  13. From hybrid-media system to hybrid-media politicians

    DEFF Research Database (Denmark)

    Blach-Ørsten, Mark; Eberholst, Mads Kæmsgaard; Burkal, Rasmus

    2017-01-01

    media use is changing rapidly; 15%–16% of Danish candidates used Twitter in 2011 but 68% in 2015. In this large-sample content analysis, party leaders have high traditional-news-media and low Twitter presence, and younger candidates visa-versa, but some politicians have high presence in both. Hybrid...

  14. Expanding Media Reach

    Centers for Disease Control (CDC) Podcasts

    2007-11-01

    In this podcast, two nurses serving a Chinese American community show how they have used local ethnic media to communicate health messages.  Created: 11/1/2007 by National Diabetes Education Program (NDEP), a joint program of the Centers for Disease Control and Prevention and the National Institutes of Health.   Date Released: 11/11/2007.

  15. 77 FR 13061 - Electronic Reporting of Toxics Release Inventory Data

    Science.gov (United States)

    2012-03-05

    ...--Reporting Year SIC--Standard Industrial Code TRI--Toxics Release Inventory TRI-ME--TRI-Made Easy Desktop... EPA to ``publish a uniform toxic chemical release form for facilities covered'' by the TRI Program. 42... practicable. Similarly, EPA's Cross-Media Electronic Reporting Regulation (CROMERR) (40 CFR Part 3), published...

  16. Radionuclide release from simulated waste material after biogeochemical leaching of uraniferous mineral samples

    International Nuclear Information System (INIS)

    Williamson, Aimee Lynn; Caron, François; Spiers, Graeme

    2014-01-01

    Biogeochemical mineral dissolution is a promising method for the released of metals in low-grade host mineralization that contain sulphidic minerals. The application of biogeochemical mineral dissolution to engineered leach heap piles in the Elliot Lake region may be considered as a promising passive technology for the economic recovery of low grade Uranium-bearing ores. In the current investigation, the decrease of radiological activity of uraniferous mineral material after biogeochemical mineral dissolution is quantified by gamma spectroscopy and compared to the results from digestion/ICP-MS analysis of the ore materials to determine if gamma spectroscopy is a simple, viable alternative quantification method for heavy nuclides. The potential release of Uranium (U) and Radium-226 ( 226 Ra) to the aqueous environment from samples that have been treated to represent various stages of leaching and passive closure processes are assessed. Dissolution of U from the solid phase has occurred during biogeochemical mineral dissolution in the presence of Acidithiobacillus ferrooxidans, with gamma spectroscopy indicating an 84% decrease in Uranium-235 ( 235 U) content, a value in accordance with the data obtained by dissolution chemistry. Gamma spectroscopy data indicate that only 30% of the 226 Ra was removed during the biogeochemical mineral dissolution. Chemical inhibition and passivation treatments of waste materials following the biogeochemical mineral dissolution offer greater protection against residual U and 226 Ra leaching. Pacified samples resist the release of 226 Ra contained in the mineral phase and may offer more protection to the aqueous environment for the long term, compared to untreated or inhibited residues, and should be taken into account for future decommissioning. - Highlights: • Gamma counting showed an 84% decrease in 235 U after biogeochemical mineral leaching. • Chemical digestion/ICP-MS analysis also showed an 84% decrease in total U. • Over

  17. The Sloan Digital Sky Survey Quasar Lens Search. IV. Statistical Lens Sample from the Fifth Data Release

    Energy Technology Data Exchange (ETDEWEB)

    Inada, Naohisa; /Wako, RIKEN /Tokyo U., ICEPP; Oguri, Masamune; /Natl. Astron. Observ. of Japan /Stanford U., Phys. Dept.; Shin, Min-Su; /Michigan U. /Princeton U. Observ.; Kayo, Issha; /Tokyo U., ICRR; Strauss, Michael A.; /Princeton U. Observ.; Hennawi, Joseph F.; /UC, Berkeley /Heidelberg, Max Planck Inst. Astron.; Morokuma, Tomoki; /Natl. Astron. Observ. of Japan; Becker, Robert H.; /LLNL, Livermore /UC, Davis; White, Richard L.; /Baltimore, Space Telescope Sci.; Kochanek, Christopher S.; /Ohio State U.; Gregg, Michael D.; /LLNL, Livermore /UC, Davis /Exeter U.

    2010-05-01

    We present the second report of our systematic search for strongly lensed quasars from the data of the Sloan Digital Sky Survey (SDSS). From extensive follow-up observations of 136 candidate objects, we find 36 lenses in the full sample of 77,429 spectroscopically confirmed quasars in the SDSS Data Release 5. We then define a complete sample of 19 lenses, including 11 from our previous search in the SDSS Data Release 3, from the sample of 36,287 quasars with i < 19.1 in the redshift range 0.6 < z < 2.2, where we require the lenses to have image separations of 1 < {theta} < 20 and i-band magnitude differences between the two images smaller than 1.25 mag. Among the 19 lensed quasars, 3 have quadruple-image configurations, while the remaining 16 show double images. This lens sample constrains the cosmological constant to be {Omega}{sub {Lambda}} = 0.84{sub -0.08}{sup +0.06}(stat.){sub -0.07}{sup + 0.09}(syst.) assuming a flat universe, which is in good agreement with other cosmological observations. We also report the discoveries of 7 binary quasars with separations ranging from 1.1 to 16.6, which are identified in the course of our lens survey. This study concludes the construction of our statistical lens sample in the full SDSS-I data set.

  18. 32 CFR 705.6 - Releasing public information material to the media.

    Science.gov (United States)

    2010-07-01

    ... UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS PUBLIC AFFAIRS REGULATIONS § 705.6 Releasing public... and/or as approved by the Assistant Secretary of Defense (Public Affairs). (i) Overall responsibility for release of information rests with the Assistant Secretary of Defense (Public Affairs). The Chief...

  19. News Media and Diplomacy: Roles, Relationships and Communication Systems.

    Science.gov (United States)

    Bullion, Stuart James

    Reflecting and influencing foreign policy, the mass media are important, if nontraditional, diplomatic channels. The role the news media assume, ranging from neutral to participant, depends largely on the society within which it operates. Journalists in authoritarian governments, for example, who rely on press releases and briefings of foreign…

  20. Training Materials for Release 3

    DEFF Research Database (Denmark)

    Wake, Jo Dugstad; Hansen, Cecilie; Debus, Kolja

    This document, D7.4 – training materials for release 3, provides an overview of the training material for version 3 of the NEXT-TELL tools and methods. Previous documents submitted as part of work package 7, which is about teacher training, are D7.1 – Training Concept, D7.2 – Training Materials...... for Release 1 and D7.3 – Training Materials for Release 2. D7.4 builds on D7.1 and D7.2 and D7.3. D7.4 contains further development of previous work within WP7, essentially a revised theoretical approach to the teacher training, and expansion of the notion of tool training. The media in use have been expanded...

  1. Adverse reactions to intravascularly administered contrast media

    International Nuclear Information System (INIS)

    Olin, T.

    1986-01-01

    A hypothesis is formulated about the mechanisms causing adverse reactions to contrast media. Contrast media act in two ways. They stimulate the mast cells to release histamine and leukotrienes, and they inhibit the enzymes which otherwise degrade leukotrienes. Thus individuals, especially those with a history of allergy, are easily exposed to undue amounts of leukotrienes and these are responsible for the adverse reactions. (orig.)

  2. Islam, Media, dan Politik : Sebuah Perdebatan dan Kontempelasi Nilai Berdemokrasi

    Directory of Open Access Journals (Sweden)

    Idil Akbar

    2016-10-01

    Full Text Available Infact, press or media is one of pilar democracy. Media in democracy is a public sphere to communi-cation and makes relation, and a same time as public arena to gain information. But, media also could not release from streotypes and tendency that usually bring of interest, either the owner or ideology. It is meaning media can not released from perspective distorsion, values bias and take a side. Media also effective to become propaganda instrument for a political interest and an ideology. It is seen like how media in US, for example, stereotype of Islam in discourses contradiction and glob-al interest opposition. Then, Islam dominantly identified as doctrine teaches radicalism, fundamen-talism and terorism. Thus, it is often be justification for US to operate the military mission in the name of democracy. Tak dipungkiri pers atau media menjadi salah satu pilar bagi demokrasi. Media dalam demokrasi adalah sebagai ruang bagi publik berkomunikasi dan berinteraksi, sekaligus sarana publik mem-peroleh informasi tentang banyak hal. Namun, media juga tak bisa dilepaskan dari stereotip dan kecenderungan-kecenderungan, yang biasanya membawa kepentingan, baik pemilik maupun ide-ologi. Media karenanya tak lepas dari distorsi perspektif, bias nilai dan berpihak. Media juga efektif menjadi alat propaganda bagi sebuah kepentingan politik dan ideologi, seperti bagaimana media di negara Amerika, misalnya, menstereotipkan Islam dalam analisis pertentangan wacana dan kepent-ingan global. Sehingga, dominan Islam diidentikkan dengan sematan sebagai ajaran yang mengajarkan radikalisme, fundamentalisme dan terorisme. Karenanya pula seringkali menjadi alasan pembenar bagi Amerika untuk menjalankan misi militer atas nama demokrasi.

  3. PDS Archive Release of Apollo 11, Apollo 12, and Apollo 17 Lunar Rock Sample Images

    Science.gov (United States)

    Garcia, P. A.; Stefanov, W. L.; Lofgren, G. E.; Todd, N. S.; Gaddis, L. R.

    2013-01-01

    Scientists at the Johnson Space Center (JSC) Lunar Sample Laboratory, Information Resources Directorate, and Image Science & Analysis Laboratory have been working to digitize (scan) the original film negatives of Apollo Lunar Rock Sample photographs [1, 2]. The rock samples, and associated regolith and lunar core samples, were obtained during the Apollo 11, 12, 14, 15, 16 and 17 missions. The images allow scientists to view the individual rock samples in their original or subdivided state prior to requesting physical samples for their research. In cases where access to the actual physical samples is not practical, the images provide an alternate mechanism for study of the subject samples. As the negatives are being scanned, they have been formatted and documented for permanent archive in the NASA Planetary Data System (PDS). The Astromaterials Research and Exploration Science Directorate (which includes the Lunar Sample Laboratory and Image Science & Analysis Laboratory) at JSC is working collaboratively with the Imaging Node of the PDS on the archiving of these valuable data. The PDS Imaging Node is now pleased to announce the release of the image archives for Apollo missions 11, 12, and 17.

  4. Comparative evaluation of Strepto B ID chromogenic medium and Granada media for the detection of Group B streptococcus from vaginal samples of pregnant women.

    Science.gov (United States)

    Tazi, Asmaa; Réglier-Poupet, Hélène; Dautezac, François; Raymond, Josette; Poyart, Claire

    2008-06-01

    Two types of selective media, the chromogenic medium Strepto B ID and two non-chromogenic media Strepto B agar and the Granada medium, were tested and compared to blood agar plates (BAP) for screening of Group B streptococcus vaginal colonization in pregnant women. All tested media were comparable in terms of sensitivity however, their use in routine laboratories may markedly facilitate the rapid detection of GBS in vaginal samples.

  5. COMPARISON OF IMMUNOASSAY AND GAS CHROMATOGRAPHY/MASS SPECTROMETRY METHODS FOR MEASURING 3,5,6-TRICHLORO-2PYRIDINOL IN MULTIPLE SAMPLE MEDIA

    Science.gov (United States)

    Two enzyme-linked immunosorbent assay (ELISA) methods were evaluated for the determination of 3,5,6-trichloro-2-pyridinol (3,5,6-TCP) in multiple sample media (dust, soil, food, and urine). The dust and soil samples were analyzed by a commercial RaPID immunoassay testing kit. ...

  6. Ultraviolet radiation stimulates the release of arachidonic acid from mammalian cells in culture

    International Nuclear Information System (INIS)

    De Leo, V.A.; Hanson, D.; Weinstein, I.B.; Harber, L.C.

    1985-01-01

    C3H 10T1/2 cells in culture were prelabelled with [ 3 H]arachidonic acid and exposed to UVB radiation. Almost immediately after irradiation cells released labelled arachidonate metabolites into media in a dose dependent manner. This release was inhibited by removing calcium ions from the system and by the addition of dexamethasone and parabromophenacyl bromide to the system. This suggests that the UVB stimulated release of arachidonic acid from membrane phospholipids is, in part, mediated by a phospholipase A 2 enzyme system. Thin layer chromatographic examination of media extracts revealed a dose dependent UVB stimulation of prostaglandin production by cultured cells. (author)

  7. HIV/AIDS stigma among a sample of primarily African-American and Latino men who have sex with men social media users.

    Science.gov (United States)

    Garett, Renee; Smith, Justin; Chiu, Jason; Young, Sean D

    2016-01-01

    The recent increase in social media use allows these technologies to rapidly reach communities with higher HIV prevalence, such as African-American and Latino men who have sex with men (MSM). However, no studies have looked at HIV/AIDS stigma among social media users from African-American and Latino MSM communities, or the association between stigma and social media use among these groups. This study sought to assess the level of HIV/AIDS stigma among a sample of social media-using African-American and Latino MSM from Los Angeles. A total of 112 (primarily African-American and Latino, n = 98, 88%) MSM Facebook users completed a survey on demographics, online social network use, and HIV/AIDS stigma. A composite stigma score was created by taking the cumulative score from a 15-item stigma questionnaire. Cumulative logistic models were used to assess the association between HIV/AIDS stigma and online social network use. In general, participants reported a low level of HIV/AIDS stigma (mean = 22.2/75, SD = 5.74). HIV/AIDS stigma composite score was significantly associated with increased time spent on online social networks each day (Adjusted odds ratios (AOR): 1.07, 95% CI: 1.00, 1.15). Among this diverse sample of MSM online social network users, findings suggest that HIV/AIDS stigma is associated with usage of social media. We discuss the implications of this work for future HIV prevention.

  8. Cesium migration experiments in different media

    International Nuclear Information System (INIS)

    Tello, C.C.O. de

    1992-01-01

    The environmental impact caused by the radioactive waste disposal depends on many factors, mainly on the release pathways of the radionuclides from the waste product to the environment. The migration of the radioelements through the different barriers, which compose the disposal system, is considered the main via for this release. This paper describes the experiments carried out to improve the cemented waste quality, as well to assess the cesium migration in different media. (author)

  9. Solubility limited radionuclide transport through geologic media

    International Nuclear Information System (INIS)

    Muraoka, Susumu; Iwamoto, Fumio; Pigford, T.H.

    1980-11-01

    Prior analyses for the migration of radionuclides neglect solubility limits of resolved radionuclide in geologic media. But actually some of the actinides may appear in chemical forms of very low solubility. In the present report we have proposed the migration model with no decay parents in which concentration of radionuclide is limited in concentration of solubility in ground water. In addition, the analytical solutions of the space-time-dependent concentration are presented in the case of step release, band release and exponential release. (author)

  10. Influence of radiographic contrast media (Iodixanol and Iomeprol) on the endothelin-1 release from human arterial and venous endothelial cells cultured on an extracellular matrix.

    Science.gov (United States)

    Franke, R P; Fuhrmann, R; Hiebl, B; Jung, F

    2012-01-01

    Various radiographic contrast media (RCM) are available for visualization of blood vessels in interventional cardiology which can vary widely in their physicochemical properties thereby influencing different functions of blood cells. In the in vitro study described here the influence of two RCMs on arterial as well as on venous endothelial cells was compared to control cultures and examined under statical culture conditions, thus eliminating the influence of RCM viscosity almost completely. The supplementation of the culture medium with RCM (30% v/v) resulted in clearly different reactions of the endothelial cells exposed. Exposition to Iodixanol supplemented culture medium was followed by endothelin-1 release from venous endothelial cells which was equivalent to the endothelin-1 release from venous control cultures. Compared to control cultures, venous endothelial cells exposed to culture medium supplemented with Iomeprol displayed a completely different reaction, the increase in endothelin-1 secretion was missing completely after a 12 hours exposure. Following a 12 hours exposure to both RCMs there were no longer endothelial cells adherent, neither in venous nor in arterial endothelial cell cultures. The study showed that not the wall shear stress was responsible for the differing effects visible after 1.5 min, 5 min, and 12 hours exposure to culture media supplemented with RCM but differences in chemotoxicity of the RCM applied.

  11. 'Frozen' media subsidies during a time of media change

    DEFF Research Database (Denmark)

    Nielsen, Rasmus Kleis

    2014-01-01

    documents and secondary sources, I show that media subsidies have largely remained frozen in their late-20th century form. The absence of major reform means that media subsidies are increasingly subject to policy drift, a process by which the operations and effectiveness of policies change not because......Media systems around the world have changed in significant ways in the early 21st century. In this article, I analyse how various forms of media subsidies have changed in response to these transformations in a sample of six different affluent democracies. On the basis of interviews, official......) a perceived shortage of desirable, cost-effective, and governable alternatives to existing policies....

  12. Crisis exercises with simulated media pressure

    International Nuclear Information System (INIS)

    Bouchot, E.; Robin, M.

    2016-01-01

    Communication in a nuclear crisis presents always a certain degree of psychic tension due to collective stress, a multiplicity of the actors, the complexity of the situation, and a lot of requests from media, NGO or local elected officials. A bad communication in a crisis situation can jeopardize the trust in the authorities and discourage population to follow sanitary recommendations and the efficiency of the protective measures can then be threatened. So training in crisis communication has become a necessity and is now fully integrated in crisis exercises. Simulated media pressure (SMP) is wielded by a specialized agency that will test the clarity, consistency and the relevancy of the pieces of information released by the communication cells through interviews, press statements, official releases or messages to social networks. A feedback analysis is always made to point out the weaknesses. (A.C.)

  13. Release of a Poorly Soluble Drug from Hydrophobically Modified Poly (Acrylic Acid in Simulated Intestinal Fluids.

    Directory of Open Access Journals (Sweden)

    Patrik Knöös

    Full Text Available A large part of new pharmaceutical substances are characterized by a poor solubility and high hydrophobicity, which might lead to a difference in drug adsorption between fasted and fed patients. We have previously evaluated the release of hydrophobic drugs from tablets based on Pemulen TR2 and showed that the release can be manipulated by adding surfactants. Here we further evaluate the possibility to use Pemulen TR2 in controlled release tablet formulations containing a poorly soluble substance, griseofulvin. The release is evaluated in simulated intestinal media that model the fasted state (FaSSIF medium or fed state (FeSSIF. The rheology of polymer gels is studied in separate experiments, in order to gain more information on possible interactions. The release of griseofulvin in tablets without surfactant varied greatly and the slowest release were observed in FeSSIF. Addition of SDS to the tablets eliminated the differences and all tablets showed a slow linear release, which is of obvious relevance for robust drug delivery. Comparing the data from the release studies and the rheology experiment showed that the effects on the release from the different media could to a large extent be rationalised as a consequence of the interactions between the polymer and the surfactants in the media. The study shows that Pemulen TR2 is a candidate for controlled release formulations in which addition of surfactant provides a way to eliminate food effects on the release profile. However, the formulation used needs to be designed to give a faster release rate than the tablets currently investigated.

  14. Model for calculating shock loading and release paths for multicomponent geologic media

    International Nuclear Information System (INIS)

    Butkovich, T.R.; Moran, B.; Burton, D.E.

    1981-07-01

    A model has been devised to calculate shock Hugoniots and release paths off the Hugoniots for multicomponent rocks containing silicate, carbonate, and water. Hugoniot equations of state are constructed from relatively simple measurements of rock properties including bulk density, grain density of the silicate component, and weight fractions of water and carbonate. Release paths off the composite Hugoniot are calculated by mixing release paths off the component Hugoniots according to their weight fractions. If the shock imparts sufficient energy to the component to cause vaporization, a gas equation of state is used to calculate the release paths. For less energetic shocks, the rock component will unload like a solid or liquid, taking into account the irreversible removal of air-filled porosity

  15. Amoco/Environmental Protection Agency Pollution Prevention Project, Yorktown refinery. Refinery release inventory. Final report

    International Nuclear Information System (INIS)

    Klee, H.; Kizier, G.J.; Baloo, S.; Hockman, E.L.; Couzens-Roberts, C.

    1992-07-01

    The report volume summarizes physical data obtained during a 2-year pollution prevention study of Amoco Oil Company's Yorktown Virginia Refinery. The study was jointly sponsored as a cooperative effort of Amoco Corporation and the United States Environmental Protection Agency. A multi-media sampling program was used to identify potential pollution sources within the Refinery. Sampling and analysis included air, surface water, groundwater, and solid waste data. Public perceptions about environmental issues of concern in the vicinity of the Refinery were also surveyed. The inventory showed that nearly 99 percent of the releases were airborne at the facility. Most of the remainder involved land disposal of solid wastes. Specific sources of major pollutants are identified

  16. Analisis Kebutuhan Terhadap Program Multi Media Interaktif Sebagai Media Pembelajaran

    OpenAIRE

    waldopo, Waldopo

    2011-01-01

    Multimedia interactive is on instructional media that combines elements of sound, visual and text, and can interact with the users. The aim of this study is to obtain information about the needs of interactive multimedia as instructional media. If needed, what kind of subjects that need to be supported by multi-media and type of format that presented. The population are students, teachers and senior secondary school principals. Sample was taken randomly. From the results of randomization assi...

  17. Fluxgate magnetorelaxometry: a new approach to study the release properties of hydrogel cylinders and microspheres.

    Science.gov (United States)

    Wöhl-Bruhn, S; Heim, E; Schwoerer, A; Bertz, A; Harling, S; Menzel, H; Schilling, M; Ludwig, F; Bunjes, H

    2012-10-15

    Hydrogels are under investigation as long term delivery systems for biomacromolecules as active pharmaceutical ingredients. The release behavior of hydrogels can be tailored during the fabrication process. This study investigates the applicability of fluxgate magnetorelaxometry (MRX) as a tool to characterize the release properties of such long term drug delivery depots. MRX is based on the use of superparamagnetic core-shell nanoparticles as model substances. The feasibility of using superparamagnetic nanoparticles to study the degradation of and the associated release from hydrogel cylinders and hydrogel microspheres was a major point of interest. Gels prepared from two types of photo crosslinkable polymers based on modified hydroxyethylstarch, specifically hydroxyethyl starch-hydroxyethyl methacrylate (HES-HEMA) and hydroxyethyl starch-polyethylene glycol methacrylate (HES-P(EG)(6)MA), were analyzed. MRX analysis of the incorporated nanoparticles allowed to evaluate the influence of different crosslinking conditions during hydrogel production as well as to follow the increase in nanoparticle mobility as a result of hydrogel degradation during release studies. Conventional release studies with fluorescent markers (half-change method) were performed for comparison. MRX with superparamagnetic nanoparticles as model substances is a promising method to analyze pharmaceutically relevant processes such as the degradation of hydrogel drug carrier systems. In contrast to conventional release experiments MRX allows measurements in closed vials (reducing loss of sample and sampling errors), in opaque media and at low magnetic nanoparticle concentrations. Magnetic markers possess a better long-term stability than fluorescent ones and are thus also promising for the use in in vivo studies. Copyright © 2012 Elsevier B.V. All rights reserved.

  18. Prospects for the introduction of Wide Area Monitoring Using Environmental Sampling

    International Nuclear Information System (INIS)

    Wogman, N.A.

    2013-01-01

    Nuclear proliferation signatures released to the environment must be collected and distinguished from primordial and man-made backgrounds in soils, sediments, air, and surface and underground water. The delay time between the nuclear proliferation emissions and the date of the Wide-Area Environmental Sampling (WAES) analysis will determine which radionuclides would be analyzed based upon their half-lives. Various sampling and analysis technologies have been considered here for application to a WAES. Sampling procedures and equipment discussed are aimed at aquatic, airborne particulate, gas, vegetation, sediment and/or soil, and fauna media. Specific procedures must be selected based upon the application scenario; for example, sampling in the northern latitudes under freezing conditions, sampling at the equator under tropical rain-forest conditions, sampling in the mid-latitudes under desert conditions, and sampling in the marine environment require different equipment and procedures. The paper is followed by the slides of the presentation

  19. Development and characterization of colloidal silica-based slow-release permanganate gel (SRP-G): laboratory investigations.

    Science.gov (United States)

    Lee, Eung Seok; Gupta, Neha

    2014-08-01

    Slow-release permanganate (MnO4(-)) gel (SRP-G) is a hyper-saline KMnO4 solution that can be used for treating large, dilute, or deep plumes of chlorinated solvents in groundwater. Ideally, the SRP-G injected into aquifers will slowly gelate to form MnO4(-) gel in situ, and the gel will slowly releases MnO4(-). Objectives of this study were to develop SRP-G using colloidal silica as gelling solution, characterize its gelation and release kinetics, and delineate its dynamics in a saturated sandy media. The SRP-G exhibited a two-phase increase in viscosity: a lag phase characterized by little increase in viscosity followed by a short gelation phase. Gelation lag times of SRP-G solutions increased (from 0.5h to 13d) with decreasing KMnO4 concentrations (from 25 to 8 g L(-1)). Permanganate release from gelated SRP-G increased with increasing KMnO4 concentrations, and was characterized as asymptotic release with initial peak (0.9-2.2 mg min(-1)) followed by more attenuated release. Gelation lag times of SRP-G flowing in sands (linear velocity=2.1md(-1)) increased (1, 3, and 6h) with decreasing KMnO4 concentrations (25.0, 23.0, and 22.9 g L(-1)). Permanganate release from gelated SRP-Gs continued for up to 3d and was characterized as asymptotic release with an initial peak release (∼1.2 g min(-1)) followed by more attenuated release over 70h. Dilution of SRP-G by dispersion in porous media affects gelation and release kinetics. Increasing the silica concentration in the SRP-G may facilitate gelation and extend the duration of MnO4(-) release from emplaced SRP-G in porous media. Copyright © 2014. Published by Elsevier Ltd.

  20. Public Engagement in Planetary Science through Europlanet Social Media

    Science.gov (United States)

    Heenatigala, T.

    2017-09-01

    From 'Save the Hubble' campaign to ESA's Rosetta mission, social media has played a major role in public engagement and continues to grow. However, with this growing number of social media platforms and the amount of content that goes public daily, the 'noise' level is high - making it difficult to reach a good, relevant audience. Hence, it's important to use different strategies with the content created, from launching a video to live session to issue a press release. Under the Horizon 2020, the Europlanet Media Centre[1] identifies the importance of using social media for outreach. Europlanet uses primary and secondary social media platforms strategically to engage with the followers and a new audience.

  1. Degradation and protein release properties of microspheres prepared from biodegradable poly(lactide-co-glycolide) and ABA triblock copolymers: influence of buffer media on polymer erosion and bovine serum albumin release.

    Science.gov (United States)

    Bittner, B; Witt, C; Mäder, K; Kissel, T

    1999-08-05

    The aim of the present study was to investigate the influence of the chemical insertion of poly(ethylene oxide), PEO, into a poly(lactide-co-glycolide), PLG, backbone on the mechanisms of in vitro degradation and erosion of the polymer. For this purpose microspheres prepared by a modified W/O/W double emulsion technique using ABA triblock copolymers, consisting of PLG A-blocks attached to central PEO B-blocks were compared with microspheres prepared from PLG. Due to their molecular architecture the ABA triblock copolymers differed in their erosion and degradation behavior from PLG. Degradation occurred faster in the ABA polymers by cleavage of ester bonds inside the polymer backbone. Even erosion was shown to start immediately after incubation in different buffer media. By varying pH and ionic strength of the buffer it was found that both mass loss and molecular weight decay were accelerated in alkaline and acidic pH in the case of the ABA triblock copolymers. Although the pH of the medium had a moderate influence on the degradation of PLG, the molecular weight decay was not accompanied by a mass loss during the observation time. In a second set of experiments we prepared bovine serum albumin, BSA, loaded microspheres from both polymers. The release of BSA from ABA microspheres under in vitro conditions parallels the faster swelling and erosion rates. This could be confirmed by electron paramagnetic resonance, EPR, measurements with spin labeled albumin where an influx of buffer medium into the ABA microspheres was already observed within a few minutes. In contrast, PLG microspheres revealed a burst release without any erosion. The current study shows that the environmental conditions affected the degradation and erosion of the pure polymer microspheres in the same way as the release of the model protein. This leads to the conclusion that the more favorable degradation profile of the ABA triblock copolymers was responsible for the improvement of the release profile.

  2. Press Oil Final Release Survey

    Energy Technology Data Exchange (ETDEWEB)

    Whicker, Jeffrey Jay [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ruedig, Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-11

    There are forty-eight 55 gallon barrels filled with hydraulic oil that are candidates for release and recycle. This oil needs to be characterized prior to release. Principles of sampling as provided in MARSAME/MARSSIM approaches were used as guidance for sampling.

  3. Meme media and meme market architectures knowledge media for editing distributing and managing intellectual resources

    CERN Document Server

    Tanaka, Y

    2003-01-01

    "In this book, Yuzuru Tanaka proposes a powerful new paradigm: that knowledge media, or "memes," operate in a way that closely resembles the biological function of genes, with their network publishing repository working as a gene pool to accelerate the evolution of knowledge shared in our societies. In Meme Media and Meme Market Architectures: Knowledge Media for Editing, Distributing, and Managing Intellectual Resources, Tanaka outlines a ready-to-use knowledge media system, supplemented with sample media objects, which allows readers to experience the knowledge media paradigm."--Jacket.

  4. An Overview of Social Media

    Centers for Disease Control (CDC) Podcasts

    2008-12-09

    In this podcast, Erin Edgerton of CDC and Fard Johnmar of Envision Solutions discuss social media and how it can be used for public health.  Created: 12/9/2008 by National Center for Health Marketing (NCHM), Division of eHealth Marketing (DeHM).   Date Released: 12/9/2008.

  5. A numerical study of transient mass transport through a circular hole connecting two semi-infinite media

    International Nuclear Information System (INIS)

    DePaoli, D.W.; Scott, T.C.

    1993-01-01

    A numerical model of transient diffusive mass transfer through a circular hole that connects two semi-infinite media was used as a means of determining potential effects of waste container penetrations on the release of immobilized contaminants into the environment. The finite difference model as developed necessarily includes treatment of mass transport in both the waste and surrounding medium and allows calculation of release rates for cases with and without preferential adsorption and differing diffusivities of the two media. The dimensionless contaminant release rate was found to vary over several orders of magnitude depending on the product of the ratio of the distribution coefficient and the media diffusivities only. As would be intuitively expected, partitioning favoring the surrounding medium and higher relative waste medium diffusivity cause higher transport rates. There was definitely no unexpected enhancement in the release rate in the case of perforations over that of an uncontained waste form

  6. Effect of alpha irradiation on UO2 surface reactivity in aqueous media

    International Nuclear Information System (INIS)

    Jegou, C.; Muzeau, B.; Broudic, V.; Poulesquen, A.; Roudil, D.; Jorion, F.; Corbel, C.

    2005-01-01

    The option of direct disposal of spent nuclear fuel in a deep geological formation raises the need to investigate the long-term behavior of the UO 2 matrix in aqueous media subjected to α-β-γ radiation. The β-γ emitters account for most of the activity of spent fuel at the moment it is removed from the reactor, but diminish within a millennial time frame by over three orders of magnitude to less than the long-term activity. The latter persists over much longer time periods and must therefore be taken into account over a geological disposal time scale. Leaching experiments with solution renewal were carried out on UO 2 pellets doped with alpha emitters ( 238 Pu and 239 Pu) to quantify the impact of alpha irradiation on UO 2 matrix alteration. Three batches of doped UO 2 pellets with different alpha flux levels (3.30 x 10 4 , 3.30 x 10 5 , and 3.2 x 10 6 α cm -2 s -1 ) were studied. The results obtained in aerated and deaerated media immediately after sample annealing or interim storage in air provide a better understanding of the UO 2 matrix alteration mechanisms under alpha irradiation. Interim storage in air of UO 2 pellets doped with alpha emitters results in variations of the UO 2 surface reactivity, which depends on the alpha particle flux at the interface and on the interim storage duration. The variation in the surface reactivity and the greater uranium release following interim storage cannot be attributed to the effect of alpha radiolysis in aerated media since the uranium release tends toward the same value after several leaching cycles for the doped UO 2 pellet batches and spent fuel. Oxygen diffusion enhanced by alpha irradiation of the extreme surface layer and/or radiolysis of the air could account for the oxidation of the surface UO 2 to UO 2+x . However, leaching experiments performed in deaerated media after annealing the samples and preleaching the surface suggest that alpha radiolysis does indeed affect the dissolution, which varies with the

  7. Comparative evaluation of metal ions release from titanium and Ti-6Al-7Nb into bio-fluids

    Directory of Open Access Journals (Sweden)

    Lori A Joseph

    2009-01-01

    Full Text Available Background: The study was designed to investigate the effects of pH, chloride ions and nature of some bio-fluids on the amount of metal ions released from titanium and TiAl 6 Nb 7 plates following incubation in actual and simulated bio-fluids over time. Methods: The amounts of released metal ions from commercially pure titanium (CpTi and TiAl 6 Nb 7 of surgical grade on immersion in 20 mL Hank′s solution of pH 4.0 or 7.0, Hank′s solution of high chloride ions concentration, Whole Blood Serum (WBS and Phosphate Buffered Saline (PBS at 37° C were determined over an incubation time of 20 weeks using atomic absorption spectrophotometry. The levels of released metal ions were compared by two-way ANOVA and Duncan′s post-hoc tests. The amounts of titanium ions released by the samples were analyzed by Pearson′s correlation. Results: TiAl 6 Nb 7 plate showed no release of Ti ions into the test solutions until after 12 weeks of incubation, while Ti ions were released from the CpTi plate from the 1 day immersion time. The re-lease of measurable amount of Al ions from TiAl 6 Nb 7 was after 12 weeks of incubation. The rate of release of Ti and Al ions from the samples increased initially with incubation time and then stabilized due to adsorption-desorption equilibrium. Conclusion: The results showed that variations in pH and chloride ions of the test media has a sig-nificant effect on the amounts of Ti ions released, while increase in chloride ions concentration sig-nificantly elevates the release of Al ions into the bio-fluids.

  8. Synthesis of pH-sensitive poly(β-amino ester)-coated mesoporous silica nanoparticles for the controlled release of drugs

    Science.gov (United States)

    Talavera-Pech, William A.; Esparza-Ruiz, Adriana; Quintana-Owen, Patricia; Vilchis-Nestor, Alfredo R.; Barrón-Zambrano, Jesus A.; Ávila-Ortega, Alejandro

    2018-03-01

    This report describes the synthesis of a controlled drug delivery system that was obtained by coating mesoporous silica nanoparticles (MSNs) with poly(β-amino ester) (PbAE), which is a solid and stable material at physiological pH, but is dissolved at acidic pH values, such as those in tumor tissues (from 5.0 to 6.5). To synthesize the system, PbAE chains were grafted onto amino-functionalized MSNs through a reaction between the surface amino groups of MSNs and the ends of acrylate chains of a PbAE. The system was physicochemically characterized by dynamic light scattering (DLS), Fourier transform infrared spectroscopy, transmission electron microscopy, thermogravimetric analysis, X-ray photoelectron spectrometry, and X-ray diffraction analyses. In addition, the in vitro release of doxorubicin (DOX) and doxycycline (DXY) in acidic and physiological media was evaluated. It was observed that the PbAE modification did not affect the mesoporous structure of MSNs. When the amount of 3-aminopropyltriethoxysilane was increased during functionalization, the amount of PbAE binding to MSNs increased as well. With respect to drug release, the sample with the highest amount of PbAE showed better control in the delivery of DXY and DOX in acidic media, because at pH 5.5, the release of both drugs was 40% higher than that at pH 7.4. These results reveal two aspects about the presence of PbAE in MSNs: PbAE does not affect the mesoporous structure of the nanoparticles, and PbAE is the main factor controlling the delivery of drugs in acidic media.

  9. Controlled release hydrophilic matrix tablet formulations of isoniazid: design and in vitro studies.

    Science.gov (United States)

    Hiremath, Praveen S; Saha, Ranendra N

    2008-01-01

    The aim of the present investigation was to develop oral controlled release matrix tablet formulations of isoniazid using hydroxypropyl methylcellulose (HPMC) as a hydrophilic release retardant polymer and to study the influence of various formulation factors like proportion of the polymer, polymer viscosity grade, compression force, and release media on the in vitro release characteristics of the drug. The formulations were developed using wet granulation technology. The in vitro release studies were performed using US Pharmacopoeia type 1 apparatus (basket method) in 900 ml of pH 7.4 phosphate buffer at 100 rpm. The release kinetics was analyzed using Korsmeyer-Peppas model. The release profiles were also analyzed using statistical method (one-way analysis of variance) and f (2) metric values. The release profiles found to follow Higuchi's square root kinetics model irrespective of the polymer ratio and the viscosity grade used. The results in the present investigation confirm that the release rate of the drug from the HPMC matrices is highly influenced by the drug/HPMC ratio and viscosity grade of the HPMC. Also, the effect of compression force and release media was found to be significant on the release profiles of isoniazid from HPMC matrix tablets. The release mechanism was found to be anomalous non-Fickian diffusion in all the cases. In the present investigation, a series of controlled release formulations of isoniazid were developed with different release rates and duration so that these formulations could further be assessed from the in vivo bioavailability studies. The formulations were found to be stable and reproducible.

  10. Tissue reactions to bacteria-inoculated rat lead samples .2. Effect of local gentamicin release through surface-modified polyurethane tubing

    NARCIS (Netherlands)

    vanWachem, PB; vanLuyn, MJA; deWit, AW; Raatjes, D; Hendriks, M; Verhoeven, MLPM; Cahalan, PT

    A surface modification technique was developed to achieve controlled release of gentamicin from implanted polyurethane (PU) rat lead samples. PU tubing first was provided with an acrylic acid/acrylamide copolymer surface graft and then loaded with gentamicin. This surface modification technique

  11. Porous filtering media comparison through wet and dry sampling of fixed bed gasification products

    Science.gov (United States)

    Allesina, G.; Pedrazzi, S.; Montermini, L.; Giorgini, L.; Bortolani, G.; Tartarini, P.

    2014-11-01

    The syngas produced by fixed bed gasifiers contains high quantities of particulate and tars. This issue, together with its high temperature, avoids its direct exploitation without a proper cleaning and cooling process. In fact, when the syngas produced by gasification is used in an Internal Combustion engine (IC), the higher the content of tars and particulate, the higher the risk to damage the engine is. If these compounds are not properly removed, the engine may fail to run. A way to avoid engine fails is to intensify the maintenance schedule, but these stops will reduce the system profitability. From a clean syngas does not only follow higher performance of the generator, but also less pollutants in the atmosphere. When is not possible to work on the gasification reactions, the filter plays the most important role in the engine safeguard process. This work is aimed at developing and comparing different porous filters for biomass gasifiers power plants. A drum filter was developed and tested filling it with different filtering media available on the market. As a starting point, the filter was implemented in a Power Pallet 10 kW gasifier produced by the California-based company "ALL Power Labs". The original filter was replaced with different porous biomasses, such as woodchips and corn cobs. Finally, a synthetic zeolites medium was tested and compared with the biological media previously used. The Tar Sampling Protocol (TSP) and a modified "dry" method using the Silica Gel material were applied to evaluate the tars, particulate and water amount in the syngas after the filtration process. Advantages and disadvantages of every filtering media chosen were reported and discussed.

  12. Two media method for linear attenuation coefficient determination of irregular soil samples; Metodo dos dois meios para a determinacao do coeficiente de atenuacao linear de amostras irregulares de solos

    Energy Technology Data Exchange (ETDEWEB)

    Vici, Carlos Henrique Georges

    2004-07-01

    In several situations of nuclear applications, the knowledge of gamma-ray linear attenuation coefficient for irregular samples is necessary, such as in soil physics and geology. This work presents the validation of a methodology for the determination of the linear attenuation coefficient ({mu}) of irregular shape samples, in such a way that it is not necessary to know the thickness of the considered sample. With this methodology irregular soil samples (undeformed field samples) from Londrina region, north of Parana were studied. It was employed the two media method for the {mu} determination. It consists of the {mu} determination through the measurement of a gamma-ray beam attenuation by the sample sequentially immersed in two different media, with known and appropriately chosen attenuation coefficients. For comparison, the theoretical value of {mu} was calculated by the product of the mass attenuation coefficient, obtained by the WinXcom code, and the measured value of the density sample. This software employs the chemical composition of the samples and supplies a table of the mass attenuation coefficients versus the photon energy. To verify the validity of the two media method, compared with the simple gamma ray transmission method, regular pome stone samples were used. With these results for the attenuation coefficients and their respective deviations, it was possible to compare the two methods. In this way we concluded that the two media method is a good tool for the determination of the linear attenuation coefficient of irregular materials, particularly in the study of soils samples. (author)

  13. The study of selective emission lines from plasma, obtained by evaporating as sample by laser radiation in air and argon media

    International Nuclear Information System (INIS)

    Sufian, A.; Dimitrov, G.

    1993-01-01

    Ultra violet visible emission spectroscopic analysis of a plasma produced through laser interaction with a solid probe in different gaseous atmospheres is conducted. Reported are the effects of air and argon, as enveloping media, on the spectral intensities of some lines. The temperature gradient of the plasma, in different atmosphere, is also plotted. In order to improve the detection limits of individual elements, suggested are the possible areas of illuminating the slit of the spectroscopic from the plasma, in respect of the height, above the sample, when working in different gaseous media. (author)

  14. Sol-gel Derived Warfarin - Silica Composites for Controlled Drug Release.

    Science.gov (United States)

    Dolinina, Ekaterina S; Parfenyuk, Elena V

    2017-01-01

    Warfarin, commonly used anticoagulant in clinic, has serious shortcomings due to its unsatisfactory pharmacodynamics. One of the efficient ways for the improvement of pharmacological and consumer properties of drugs is the development of optimal drug delivery systems. The aim of this work is to synthesize novel warfarin - silica composites and to study in vitro the drug release kinetics to obtain the composites with controlled release. The composites of warfarin with unmodified (UMS) and mercaptopropyl modified silica (MPMS) were synthesized by sol-gel method. The composite formation was confirmed by FTIR spectra. The concentrations of warfarin released to media with pH 1.6, 6.8 and 7.4 were measured using UV spectroscopy. The drug release profiles from the solid composites were described by a series of kinetic models which includes zero order kinetics, first order kinetics, the modified Korsmeyer-Peppas model and Hixson-Crowell model. The synthesized sol-gel composites have different kinetic behavior in the studied media. In contrast to the warfarin composite with unmodified silica, the drug release from the composite with mercaptopropyl modified silica follows zero order kinetics for 24 h irrespective to the release medium pH due to mixed mechanism (duffusion + degradation and/or disintegration of silica matrix). The obtained results showed that warfarin - silica sol-gel composites have a potential application for the development of novel oral formulation of the drug with controlled delivery. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  15. New Media Institute – Personal Public Service Announcement Project

    Centers for Disease Control (CDC) Podcasts

    2009-05-15

    In this podcast, Erin Edgerton, CDC, and Scott Shamp, New Media Institute, University of Georgia, discuss new media and the personal public service announcement project.  Created: 5/15/2009 by National Center for Health Marketing (NCHM), Division of eHealth Marketing (DeHM).   Date Released: 2/10/2010.

  16. Measurement of fission gases released by HTR irradiation samples in the BR 2 reactor (Mol/Belgium)

    International Nuclear Information System (INIS)

    Koetter, H.; Mueller, H.B.

    1975-04-01

    During the irradiation of HTR-test fuel (coated particles resp. compacts) the release rate of fission gases is measured automatically. For that purpose the γ-spectrum of the sweep gas is analyzed with respect to the isotopes Xe-133, Xe-135, Xe-135sup(m), Xe-137, Xe-138, Kr-85sup(m), Kr-87, Kr-88, Kr-89. Gas sampling, spectral analysis, data handling and evaluation are controlled by computer. (orig.) [de

  17. Neoteric Media as Tools for Process Intensification

    Science.gov (United States)

    Beh, C. C.; Mammucari, R.; Foster, N. R.

    2017-06-01

    Process intensification (PI) is a commonly used term in the chemical processing industry. When the concept of PI was first introduced in the late 1970s within the Imperial Chemical Industries (ICI) company, the main impetus was to reduce the processing cost without impairing the production rate. Neoteric media present as alternatives in chemical processing include gas-expanded liquids, ionic liquids, subcritical water, and combination of gas-expanded liquids and ionic liquids. The applications of neoteric media include particle engineering for improved bioavailability, controlled release of therapeutic implants, pharmaceutical formulations, extraction of natural products, nano-carriers for drug delivery, sterilisation of implants, and chemical reactions. This paper provides an overview of the use of these neoteric media.

  18. Release behavior of drugs from various natural gums and polymers.

    Science.gov (United States)

    Singh, Anupama; Sharma, Pramod Kumar; Malviya, Rishabha

    2011-01-01

    Polymers are the high molecular weight compounds of natural or synthetic origin, widely used in drug delivery of formulations. These polymers are further classified as hydrophilic or hydrophobic in nature. Depending upon this characteristic, polymers exhibit different release behavior in different media. This property plays an important role in the selection of polymers for controlled, sustained or immediate release formulations. The review highlights the literatures related to the research made on several polymers regarding the release kinetics which made them a novel approach for modifying the action of the particular formulation.

  19. Effect of alpha irradiation on UO{sub 2} surface reactivity in aqueous media

    Energy Technology Data Exchange (ETDEWEB)

    Jegou, C.; Muzeau, B.; Broudic, V.; Poulesquen, A.; Roudil, D. [Commissariat a l' Energie Atomique (CEA), Rhone Valley Research Center, DIEC/SESC/LMPA, Bagnols-sur-Ceze (France); Jorion, F. [Commissariat a l' Energie Atomique (CEA), Rhone Valley Research Center, DRCP/SE2A/LEMA, Bagnols-sur-Ceze (France); Corbel, C. [Commissariat a l' Energie Atomique (CEA), Saclay Research Center, DSM/DRECAM/SCM, Gif sur Yvette (France)

    2005-07-01

    The option of direct disposal of spent nuclear fuel in a deep geological formation raises the need to investigate the long-term behavior of the UO{sub 2} matrix in aqueous media subjected to {alpha}-{beta}-{gamma} radiation. The {beta}-{gamma} emitters account for most of the activity of spent fuel at the moment it is removed from the reactor, but diminish within a millennial time frame by over three orders of magnitude to less than the long-term activity. The latter persists over much longer time periods and must therefore be taken into account over a geological disposal time scale. Leaching experiments with solution renewal were carried out on UO{sub 2} pellets doped with alpha emitters ({sup 238}Pu and {sup 239}Pu) to quantify the impact of alpha irradiation on UO{sub 2} matrix alteration. Three batches of doped UO{sub 2} pellets with different alpha flux levels (3.30 x 10{sup 4}, 3.30 x 10{sup 5}, and 3.2 x 10{sup 6} {alpha} cm{sup -2} s{sup -1}) were studied. The results obtained in aerated and deaerated media immediately after sample annealing or interim storage in air provide a better understanding of the UO{sub 2} matrix alteration mechanisms under alpha irradiation. Interim storage in air of UO{sub 2} pellets doped with alpha emitters results in variations of the UO{sub 2} surface reactivity, which depends on the alpha particle flux at the interface and on the interim storage duration. The variation in the surface reactivity and the greater uranium release following interim storage cannot be attributed to the effect of alpha radiolysis in aerated media since the uranium release tends toward the same value after several leaching cycles for the doped UO{sub 2} pellet batches and spent fuel. Oxygen diffusion enhanced by alpha irradiation of the extreme surface layer and/or radiolysis of the air could account for the oxidation of the surface UO{sub 2} to UO{sub 2+x}. However, leaching experiments performed in deaerated media after annealing the samples and

  20. On the Ni-Ion release rate from surfaces of binary NiTi shape memory alloys

    Science.gov (United States)

    Ševčíková, Jana; Bártková, Denisa; Goldbergová, Monika; Kuběnová, Monika; Čermák, Jiří; Frenzel, Jan; Weiser, Adam; Dlouhý, Antonín

    2018-01-01

    The study is focused on Ni-ion release rates from NiTi surfaces exposed in the cell culture media and human vascular endothelial cell (HUVEC) culture environments. The NiTi surface layers situated in the depth of 70 μm below a NiTi oxide scale are affected by interactions between the NiTi alloys and the bio-environments. The finding was proved with use of inductively coupled plasma mass spectrometry and electron microscopy experiments. As the exclusive factor controlling the Ni-ion release rates was not only thicknesses of the oxide scale, but also the passivation depth, which was two-fold larger. Our experimental data strongly suggested that some other factors, in addition to the Ni concentration in the oxide scale, admittedly hydrogen soaking deep below the oxide scale, must be taken into account in order to rationalize the concentrations of Ni-ions released into the bio-environments. The suggested role of hydrogen as the surface passivation agent is also in line with the fact that the Ni-ion release rates considerably decrease in NiTi samples that were annealed in controlled hydrogen atmospheres prior to bio-environmental exposures.

  1. Assessing sentiment in conflict zones through social media

    OpenAIRE

    Bourret, Andrew K.; Wines, Joshua D.; Mendes, Jason M.

    2016-01-01

    Approved for public release; distribution is unlimited While it is widely accepted that polling can assess levels of popular support in a geographic area by surveying a cross-segment of its population, it is less well accepted that analysts can use social media analysis to assess sentiment or popular support within the same space. We examine this question by comparing geographically anchored polling and social media data, utilizing over 1.4 million geo-referenced messages sent through the ...

  2. The Role of Social Media in New Movie Marketing

    OpenAIRE

    Griffin, Hali

    2012-01-01

    The study aims to enhance understanding of social media’s impact on and role within marketing strategy for new release films. Current literature on social media and film marketing has a predominantly consumer-oriented focus. This study examines perceptions of social media from the perspective of marketing practitioners, including knowledgeable filmmakers and other professionals with film marketing expertise. This study utilized semi-structured interviews to explore professional perspectives o...

  3. Sol-gel-based SPME fiber as a reliable sampling technique for studying biogenic volatile organic compounds released from Clostridium tetani.

    Science.gov (United States)

    Ghader, Masoud; Shokoufi, Nader; Es-Haghi, Ali; Kargosha, Kazem

    2017-11-01

    A novel and efficient headspace solid-phase microextraction (HS-SPME) method, followed by gas chromatography mass spectrometry (GC-MS), was developed to study volatile organic compounds (VOCs) emerging from microorganisms. Two homemade SPME fibers, a semi-polar poly (dimethylsiloxane) (PDMS) fiber, and a polar polyethylene glycol (PEG) fiber, along with two commercial fibers (PDMS and PDMS/DVB) were used to collect VOCs emerging from Clostridium tetani which was cultured in different media. The adsorbed VOCs were desorbed and identified, in vitro, using GC-MS. The adsorption efficiency was improved by optimizing the time duration of adsorption and desorption. About 50 components were identified by the proposed method. The main detected compounds appeared to be sulfur containing compounds such as butanethioic acid S-methyl ester, dimethyl trisulfide, and dimethyl tetrasulfide. These volatile sulfur containing compounds are derived from amino acids containing the sulfur element, which probably coexist in the mentioned bacterium or are added to the culture media. The developed HS-SPME-GC-MS method allowed the determination of the chemical fingerprint of Clostridium tetani volatile constituents, and thus provides a new, simple, and reliable tool for studying the growth of microorganisms. Graphical abstract Investigation of biogenic VOCs released from Clostridium tetani using SPME-GC-MS.

  4. The news value of Dutch corporate press releases as a predictor of corporate agenda building power

    NARCIS (Netherlands)

    Schafraad, P.; van Zoonen, W.; Verhoeven, P.

    2016-01-01

    This study focuses on explaining agenda building power of corporate press releases. The purpose of the study is to investigate to what extent news factor theory can be applied to predict whether a press release generates media attention or not. A content analysis of 823 press releases from 30 of the

  5. [A methodological approach to assessing the quality of medical health information on its way from science to the mass media].

    Science.gov (United States)

    Serong, Julia; Anhäuser, Marcus; Wormer, Holger

    2015-01-01

    A current research project deals with the question of how the quality of medical health information changes on its way from the academic journal via press releases to the news media. In an exploratory study a sample of 30 news items has been selected stage-by-stage from an adjusted total sample of 1,695 journalistic news items on medical research in 2013. Using a multidimensional set of criteria the news items as well as the corresponding academic articles, abstracts and press releases are examined by science journalists and medical experts. Together with a content analysis of the expert assessments, it will be verified to what extent established quality standards for medical journalism can be applied to medical health communication and public relations or even to studies and abstracts as well. Copyright © 2015. Published by Elsevier GmbH.

  6. Influence of culture media on the physical and chemical properties of Ag-TiCN coatings

    Science.gov (United States)

    Carvalho, I.; Escobar Galindo, R.; Henriques, M.; Palacio, C.; Carvalho, S.

    2014-08-01

    The aim of this study was to verify the possible physical and chemical changes that may occur on the surface of Ag-TiCN coatings after exposure to the culture media used in microbiological and cytotoxic assays, respectively tryptic soy broth (TSB) and Dulbecco's modified eagle's medium (DMEM). After sample immersion for 24 h in the media, analyses were performed by glow discharge optical emission spectroscopy discharge radiation (GDOES), Rutherford backscattering spectroscopy (RBS) and x-ray photoelectron spectroscopy (XPS). The results of GDOES profile, RBS and XPS spectra, of samples immersed in TSB, demonstrated the formation of a thin layer of carbon, oxygen and nitrogen that could be due to the presence of proteins in TSB. After 24 h of immersion in DMEM, the results showed the formation of a thin layer of calcium phosphates on the surface, since the coatings displayed a highly oxidized surface in which calcium and phosphorus were detected. All these results suggested that the formation of a layer on the coating surface prevented the release of silver ions in concentrations that allow antibacterial activity.

  7. Slow-release Permanganate Gel (SRP-G) for Groundwater Remediation: Spreading, Gelation, and Release in Porous and Low-Permeability Media

    Science.gov (United States)

    Lee, E. S.; Hastings, J.; Kim, Y.

    2015-12-01

    Dense nonaqueous phase liquids (DNAPLs) like trichloroethylene (TCE) serve as the most common form of groundwater pollution in the world. Pore-plugging by the solid oxidation product MnO2 and limited lateral dispersion of the oxidant are two common problems with existing in-situ chemical oxidation (ISCO) schemes that could be alleviated through the development of a delayed gelation method for oxidant delivery. The objective of the current study was to further develop and optimize slow-release permanganate gel (SRP-G), a solution comprising colloidal silica and KMnO4, as a novel low-cost treatment option for large and dilute TCE plumes in groundwater. Batch tests showed that gelation could be delayed through manipulation of KMnO4 concentration, pH, and silica particle size of the SRP-G solution. In flow-through columns and flow-tanks filled with saturated sands, silica concentration had little effect on the gelation lag stage and release rate, but increasing silica concentration was associated with increasing release duration. When compared to a pure KMnO4 solution, visual observations and [MnO4-] measurements from flow tank tests demonstrated that the SRP-G prolonged the release duration and enhanced lateral spreading of the oxidant.

  8. Media and youth: access, exposure, and privatization.

    Science.gov (United States)

    Roberts, D F

    2000-08-01

    To describe U.S. youth's access and exposure to the full array of media, as well as the social contexts in which media exposure occurs. A cross-sectional national random sample of 2065 adolescents aged 8 through 18 years, including oversamples of African-American and Hispanic youth, completed questionnaires about use of television, videotapes, movies, computers, video games, radio, compact discs, tape players, books, newspapers, and magazines. U.S. youngsters are immersed in media. Most households contain most media (computers and video game systems are the exception); the majority of youth have their own personal media. The average youth devotes 6 3/4 h to media; simultaneous use of multiple media increases exposure to 8 h of media messages daily. Overall, media exposure and exposure to individual media vary as a function of age, gender, race/ethnicity, and family socioeconomic level. Television remains the dominant medium. About one-half of the youth sampled uses a computer daily. A substantial proportion of children's and adolescents' media use occurs in the absence of parents. American youth devote more time to media than to any other waking activity, as much as one-third of each day. This demands increased parental attention and research into the effects of such extensive exposure.

  9. Analysis of Department of Defense social media policy and its impact on operational security

    OpenAIRE

    Leonhardi, Eric V.; Murphy, Mark; Kim, Hannah

    2015-01-01

    Approved for public release; distribution is unlimited The emergence and rapid adoption of social media by society has forced the Department of Defense (DOD) to adapt, and ultimately develop and incorporate, social media policy into its cybersecurity strategy. While social media has influenced DOD strategy, it has also had a direct impact on the organization’s operational security (OPSEC). DOD personnel using social media represent a potential OPSEC risk through the various ways and means ...

  10. Uranium (VI) transport in saturated heterogeneous media: Influence of kaolinite and humic acid.

    Science.gov (United States)

    Chen, Chong; Zhao, Kang; Shang, Jianying; Liu, Chongxuan; Wang, Jin; Yan, Zhifeng; Liu, Kesi; Wu, Wenliang

    2018-05-07

    Natural aquifers typically exhibit a variety of structural heterogeneities. However, the effect of mineral colloids and natural organic matter on the transport behavior of uranium (U) in saturated heterogeneous media are not totally understood. In this study, heterogeneous column experiments were conducted, and the constructed columns contained a fast-flow domain (FFD) and a slow-flow domain (SFD). The effect of kaolinite, humic acid (HA), and kaolinite/HA mixture on U(VI) retention and release in saturated heterogeneous media was examined. Media heterogeneity significantly influenced U fate and transport behavior in saturated subsurface environment. The presence of kaolinite, HA, and kaolinite/HA enhanced the mobility of U in heterogeneous media, and the mobility of U was the highest in the presence of kaolinite/HA and the lowest in the presence of kaolinite. In the presence of kaolinite, there was no difference in the amount of U released from the FFD and SFD. However, in the presence of HA and kaolinite/HA, a higher amount of U was released from the FFD. The findings in this study showed that medium structure and mineral colloids, as well as natural organic matter in the aqueous phase had significant effects on U transport and fate in subsurface environment. Copyright © 2018 Elsevier Ltd. All rights reserved.

  11. From press release to news: mapping the framing of the 2009 H1N1 A influenza pandemic.

    Science.gov (United States)

    Lee, Seow Ting; Basnyat, Iccha

    2013-01-01

    Pandemics challenge conventional assumptions about health promotion, message development, community engagement, and the role of news media. To understand the use of press releases in news coverage of pandemics, this study traces the development of framing devices from a government public health agency's press releases to news stories about the 2009 H1N1 A influenza pandemic. The communication management of the H1N1 pandemic, an international news event with local implications, by the Singapore government is a rich locus for understanding the dynamics of public relations, health communication, and journalism. A content analysis shows that the evolution of information from press release to news is marked by significant changes in media frames, including the expansion and diversification in dominant frames and emotion appeals, stronger thematic framing, more sources of information, conversion of loss frames into gain frames, and amplification of positive tone favoring the public health agency's position. Contrary to previous research that suggests that government information subsidies passed almost unchanged through media gatekeepers, the news coverage of the pandemic reflects journalists' selectivity in disseminating the government press releases and in mediating the information flow and frames from the press releases.

  12. On the intracellular release mechanism of hydrophobic cargo and its relation to the biodegradation behavior of mesoporous silica nanocarriers.

    Science.gov (United States)

    von Haartman, Eva; Lindberg, Desiré; Prabhakar, Neeraj; Rosenholm, Jessica M

    2016-12-01

    The intracellular release mechanism of hydrophobic molecules from surface-functionalized mesoporous silica nanoparticles was studied in relation to the biodegradation behavior of the nanocarrier, with the purpose of determining the dominant release mechanism for the studied drug delivery system. To be able to follow the real-time intracellular release, a hydrophobic fluorescent dye was used as model drug molecule. The in vitro release of the dye was investigated under varying conditions in terms of pH, polarity, protein and lipid content, presence of hydrophobic structures and ultimately, in live cancer cells. Results of investigating the drug delivery system show that the degradation and drug release mechanisms display a clear interdependency in simple aqueous solvents. In pure aqueous media, the cargo release was primarily dependent on the degradation of the nanocarrier, while in complex media, mimicking intracellular conditions, the physicochemical properties of the cargo molecule itself and its interaction with the carrier and/or surrounding media were found to be the main release-governing factors. Since the material degradation was retarded upon loading with hydrophobic guest molecules, the cargo could be efficiently delivered into live cancer cells and released intracellularly without pronounced premature release under extracellular conditions. From a rational design point of view, pinpointing the interdependency between these two processes can be of paramount importance considering future applications and fundamental understanding of the drug delivery system. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Literasi Media Pada Mahasiswa Prodi Ilmu Komunikasi Universitas Mulawarman

    Directory of Open Access Journals (Sweden)

    Inda Fitryarini

    2016-07-01

    Full Text Available Teen relations with the mass media has become a problematic issue. On side of the media is a means of transforming the ideas, values, norms and mental transformation towards awake, enlighment, and progress of life. On the other hand the mass media transmit a bad influencethat degrades humanity format and the ability to think of teenagers. The adverse effect of the mass media, gave to be idea of the so called media literacy. The purpose of the study is to describe and analyze the step of media literacy among the students of Mulawarman University, Communication studies in Faculty Social and Politic Science. To achieve these objectives the researcher used descriptive qualitative method. The primary data obtained from semi structured interview and observations. And secondary data obtained through documentation and literature.the sampling technique used is purposive sampling. The result of discussion, it can be conclude that media literacy among 9 adolescents in communication studies program 2014 was at early step. At this step, the audience has the ability tobe the introduction of media. Especially the positive and negative effects of potential given by the media. Relasi remaja dengan media massa telah menjadi persoalan yang problematik. Di satu sisi media adalah sarana transformasi ide, nilai, norma, dan transformasi mental ke arah penyadaran, pencerahan, dan kemajuan kehidupan. Namun disisi lain media massa menularkan pengaruh buruk yang mendegradasi format kemanusiaan dan kemampuan berpikir remaja. Dampak buruk media massa tersebut, melahirkan gagasan yang disebut media literasi. Tujuan penelitian ini adalah untuk menggambarkan dan menganalisis tahapan literasi media di kalangan 9 remaja Prodi Ilmu Komunikasi FISIP Universitas Mulawarman. Untuk mencapai tujuan tersebut, peneliti menggunakan metode kualitatif deskriptif. Data primer diperoleh melalui wawancara semistruktur dan observasi sedangkan data sekunder diperoleh melalui dokumentasi dan

  14. Media and Public Communications Policies: An Empirical Analysis of the Brazilian Print Media

    OpenAIRE

    Canela, Guilherme

    2007-01-01

    This essay examines a subject rarely emphasized in the studies on public interest issues reported in the print media. Drawing on a review of the journalistic content produced by 53 newspapers from every state in the federation and 4 national weekly magazines, the paper analyzes a sample of 1,184 articles, editorials, columns, interviews, and reports on subjects of immediate interest to the media, journalism, and/or media companies. Throughout 2003, 2004, and 2005, news pieces were compiled co...

  15. Social Media Correlates of Organizational Climate

    Science.gov (United States)

    Smith, Daniel Crane

    2009-01-01

    This research (1) gathered data from a sample of employees on their social media practices and the social media policies of their employers and (2) investigated how blogging and other social media added to a model of organizational climate that promotes (a) knowledge sharing and cooperation, and (b) trust in peers and management. The research…

  16. Evaluation of different conditions and culture media for the recovery of Aeromonas spp. from water and shellfish samples.

    Science.gov (United States)

    Latif-Eugenín, F; Beaz-Hidalgo, R; Figueras, M J

    2016-09-01

    To perform a comparative study for determining the optimum culture method (direct plating or enrichment) and medium (ampicillin dextrin agar (ADA), starch ampicillin agar (SAA), bile salts irgasan brilliant green modified (BIBG-m)) for recovering Aeromonas species from water and shellfish samples. By direct culture, Aeromonas was detected in 65% (13/20) of the water samples and in 54·5% (6/11) of the shellfish samples. However, when a pre-enrichment step was included, the number of positive water samples increased to 75% (15/20) and the ones of shellfish to 90·1% (10/11). The enriched culture significantly favoured (P culture medium for detecting Aeromonas from water was ADA. However, no differences were observed in the case of shellfish samples (P > 0·05). Isolation of Aeromonas media from water was favoured (P culture method and medium used influenced the recovery of some Aeromonas species from water and shellfish samples. This fact should be considered in future prevalence studies to avoid overestimating the above mentioned Aeromonas species. © 2016 The Society for Applied Microbiology.

  17. A media violence-inspired juvenile sexual homicide offender 13 years later.

    Science.gov (United States)

    Myers, Wade C; Eggleston, Chris F; Smoak, Pamela

    2003-11-01

    No follow-up studies exist on how minors who commit sexual homicides adjust once released back into the community. This is an important question given the extreme nature of their crimes, lack of recidivism data, and the expectation that one-half of them will be freed from prison by mid-life. Likewise, no studies exist on the role our culture's pervasive media violence plays in these offenses. This report describes a 13-year-old boy who committed a witnessed media violence-inspired sexual homicide. Follow-up information is provided on his community adjustment as an adult four years after release from prison. He had multiple indicators of brain dysfunction, and watched a "slasher" film just before committing the blitz style crime upon a female neighbor. Media violence literature is reviewed--against a backdrop of developmental abnormalities, neuropsychiatric vulnerabilities, family dysfunction, and mental illness. This case illustrates how the confluence of such variables, combined with the tinder of erotic screen violence, may lead to sexual murder.

  18. Possibilities for in-vitro testing of controlled-release parenterals.

    OpenAIRE

    Kožák, Jan

    2014-01-01

    The objective of this study was to start with the development of a gel-based medium simulating intramuscular environment for in-vitro drug release testing as an alternative to currently used water-based media. A pork meat was selected as a model of the muscle tissue. At the first part of the study, diffusion rate was proposed as the most determining factor of drug release in gel-based medium. Consequently, the diffusion rate of sodium fluorescein in pork meat was compared with the diffusion r...

  19. Release of endothelial cell lipoprotein lipase by plasma lipoproteins and free fatty acids

    International Nuclear Information System (INIS)

    Saxena, U.; Witte, L.D.; Goldberg, I.J.

    1989-01-01

    Lipoprotein lipase (LPL) bound to the lumenal surface of vascular endothelial cells is responsible for the hydrolysis of triglycerides in plasma lipoproteins. Studies were performed to investigate whether human plasma lipoproteins and/or free fatty acids would release LPL which was bound to endothelial cells. Purified bovine milk LPL was incubated with cultured porcine aortic endothelial cells resulting in the association of enzyme activity with the cells. When the cells were then incubated with media containing chylomicrons or very low density lipoproteins (VLDL), a concentration-dependent decrease in the cell-associated LPL enzymatic activity was observed. In contrast, incubation with media containing low density lipoproteins or high density lipoproteins produced a much smaller decrease in the cell-associated enzymatic activity. The addition of increasing molar ratios of oleic acid:bovine serum albumin to the media also reduced enzyme activity associated with the endothelial cells. To determine whether the decrease in LPL activity was due to release of the enzyme from the cells or inactivation of the enzyme, studies were performed utilizing radioiodinated bovine LPL. Radiolabeled LPL protein was released from endothelial cells by chylomicrons, VLDL, and by free fatty acids (i.e. oleic acid bound to bovine serum albumin). The release of radiolabeled LPL by VLDL correlated with the generation of free fatty acids from the hydrolysis of VLDL triglyceride by LPL bound to the cells. Inhibition of LPL enzymatic activity by use of a specific monoclonal antibody, reduced the extent of release of 125 I-LPL from the endothelial cells by the added VLDL. These results demonstrated that LPL enzymatic activity and protein were removed from endothelial cells by triglyceride-rich lipoproteins (chylomicrons and VLDL) and oleic acid

  20. Dense sampled transmission matrix for high resolution angular spectrum imaging through turbid media via compressed sensing (Conference Presentation)

    Science.gov (United States)

    Jang, Hwanchol; Yoon, Changhyeong; Choi, Wonshik; Eom, Tae Joong; Lee, Heung-No

    2016-03-01

    We provide an approach to improve the quality of image reconstruction in wide-field imaging through turbid media (WITM). In WITM, a calibration stage which measures the transmission matrix (TM), the set of responses of turbid medium to a set of plane waves with different incident angles, is preceded to the image recovery. Then, the TM is used for estimation of object image in image recovery stage. In this work, we aim to estimate highly resolved angular spectrum and use it for high quality image reconstruction. To this end, we propose to perform a dense sampling for TM measurement in calibration stage with finer incident angle spacing. In conventional approaches, incident angle spacing is made to be large enough so that the columns in TM are out of memory effect of turbid media. Otherwise, the columns in TM are correlated and the inversion becomes difficult. We employ compressed sensing (CS) for a successful high resolution angular spectrum recovery with dense sampled TM. CS is a relatively new information acquisition and reconstruction framework and has shown to provide superb performance in ill-conditioned inverse problems. We observe that the image quality metrics such as contrast-to-noise ratio and mean squared error are improved and the perceptual image quality is improved with reduced speckle noise in the reconstructed image. This results shows that the WITM performance can be improved only by executing dense sampling in the calibration stage and with an efficient signal reconstruction framework without elaborating the overall optical imaging systems.

  1. Aluminum corrosion product release kinetics

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, Matt, E-mail: Matthew.Edwards@cnl.ca; Semmler, Jaleh; Guzonas, Dave; Chen, Hui Qun; Toor, Arshad; Hoendermis, Seanna

    2015-07-15

    Highlights: • Release of Al corrosion product was measured in simulated post-LOCA sump solutions. • Increased boron was found to enhance Al release kinetics at similar pH. • Models of Al release as functions of time, temperature, and pH were developed. - Abstract: The kinetics of aluminum corrosion product release was examined in solutions representative of post-LOCA sump water for both pressurized water and pressurized heavy-water reactors. Coupons of AA 6061 T6 were exposed to solutions in the pH 7–11 range at 40, 60, 90 and 130 °C. Solution samples were analyzed by inductively coupled plasma atomic emission spectroscopy, and coupon samples were analyzed by secondary ion mass spectrometry. The results show a distinct “boron effect” on the release kinetics, expected to be caused by an increase in the solubility of the aluminum corrosion products. New models were developed to describe both sets of data as functions of temperature, time, and pH (where applicable)

  2. Media and Public Communications Policies: An Empirical Analysis of the Brazilian Print Media

    Directory of Open Access Journals (Sweden)

    Guilherme Canela

    2007-12-01

    Full Text Available This essay examines a subject rarely emphasized in the studies on public interest issues reported in the print media. Drawing on a review of the journalistic content produced by 53 newspapers from every state in the federation and 4 national weekly magazines, the paper analyzes a sample of 1,184 articles, editorials, columns, interviews, and reports on subjects of immediate interest to the media, journalism, and/or media companies. Throughout 2003, 2004, and 2005, news pieces were compiled containing keywords, including “media and democracy,” “concentration of ownership,” “television regulation.” The analysis found that the print media provides insufcient and inadequate coverage of these issues, reserving more extensive coverage only to those questions nearest and dearest to it, such as the freedom of expression.

  3. STORAGE STABILITY OF PESTICIDES IN EXTRACT SOLVENTS AND SAMPLING MEDIA

    Science.gov (United States)

    Demonstrating that pesticides are stable in field media and their extracts over extended storage periods allows operational flexibility and cost efficiency. Stability of the 31 neutral pesticides and 2 acid herbicides of the Agricultural Health Study exposure pilot was evaluate...

  4. Comparing human peritoneal fluid and phosphate-buffered saline for drug delivery: do we need bio-relevant media?

    Science.gov (United States)

    Bhusal, Prabhat; Rahiri, Jamie Lee; Sua, Bruce; McDonald, Jessica E; Bansal, Mahima; Hanning, Sara; Sharma, Manisha; Chandramouli, Kaushik; Harrison, Jeff; Procter, Georgina; Andrews, Gavin; Jones, David S; Hill, Andrew G; Svirskis, Darren

    2018-06-01

    An understanding of biological fluids at the site of administration is important to predict the fate of drug delivery systems in vivo. Little is known about peritoneal fluid; therefore, we have investigated this biological fluid and compared it to phosphate-buffered saline, a synthetic media commonly used for in vitro evaluation of intraperitoneal drug delivery systems. Human peritoneal fluid samples were analysed for electrolyte, protein and lipid levels. In addition, physicochemical properties were measured alongside rheological parameters. Significant inter-patient variations were observed with regard to pH (p < 0.001), buffer capacity (p < 0.05), osmolality (p < 0.001) and surface tension (p < 0.05). All the investigated physicochemical properties of peritoneal fluid differed from phosphate-buffered saline (p < 0.001). Rheological examination of peritoneal fluid demonstrated non-Newtonian shear thinning behaviour and predominantly exhibited the characteristics of an entangled network. Inter-patient and inter-day variability in the viscosity of peritoneal fluid was observed. The solubility of the local anaesthetic lidocaine in peritoneal fluid was significantly higher (p < 0.05) when compared to phosphate-buffered saline. Interestingly, the dissolution rate of lidocaine was not significantly different between the synthetic and biological media. Importantly, and with relevance to intraperitoneal drug delivery systems, the sustained release of lidocaine from a thermosensitive gel formulation occurred at a significantly faster rate into peritoneal fluid. Collectively, these data demonstrate the variation between commonly used synthetic media and human peritoneal fluid. The differences in drug release rates observed illustrate the need for bio-relevant media, which ultimately would improve in vitro-in vivo correlation.

  5. Social media policy in other orqanizations.

    Science.gov (United States)

    Sebelius, Carl L

    2012-01-01

    Most professional organizations have developed policy for use of social media by their members and several have developed Web sites to help members with ethical media use. It is commmon among businesses, nonprofit organizations, and government agencies to have policies governing use of media by employees when communicating with the public and provide employee training. This article samples some of the best practices in social media policy. Development of such policy represents an attractive opportunity for dentistry.

  6. Social Media Integration into State-Operated Fusion Centers and Local Law Enforcement: Potential Uses and Challenges

    Science.gov (United States)

    2010-12-01

    NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release; distribution is unlimited SOCIAL MEDIA...DATE December 2010 3. REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE Social Media Integration into State-Operated Fusion...technologies, particularly social media, within fusion centers and local law enforcement entities could enable a more expedient exchange of information among

  7. Media Exposure and Attitudes towards Immigrants

    Directory of Open Access Journals (Sweden)

    Álvarez-Gálvez Javier

    2014-01-01

    Full Text Available Despite evidences of the media?s infl uence on shaping the attitudes of the Spanish population towards the immigrant community, survey indicators have seldom been designed to explain the relationship between media coverage of immigrants and the attitudes of native towards this phenomenon. Using a sample of students, we examined the validity of different types of indicators used to measure the frequency of media consumption, the recall of news regarding immigration and the degree of media credibility in order to explain racist and xenophobic attitudes. Results reveal a clear association between the news media and native group attitudes towards immigration, thus demonstrating the usefulness of these indicators.

  8. 14 CFR 1213.109 - News releases concerning international activities.

    Science.gov (United States)

    2010-01-01

    ... Headquarters offices of External Relations and Public Affairs. (b) NASA Centers and Headquarters offices will report all visits proposed by representatives of foreign news media to the Public Affairs Officer of the... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false News releases concerning international...

  9. Decreasing Excessive Media Usage while Increasing Physical Activity: A Single-Subject Research Study

    Science.gov (United States)

    Larwin, Karen H.; Larwin, David A.

    2008-01-01

    The Kaiser Family Foundation released a report entitled "Kids and Media Use" in the United States that concluded that children's use of media--including television, computers, Internet, video games, and phones--may be one of the primary contributor's to the poor fitness and obesity of many of today's adolescents. The present study examines the…

  10. Pressure-sensitive release mechanism for radiosonde applications

    International Nuclear Information System (INIS)

    Kulhanek, F.C.

    1975-01-01

    As part of the 1975 planetary boundary layer field experimental program, miniature radiosondes attached to pilot balloons were released into the atmosphere for routine sampling of the vertical temperature distribution. A new releasing mechanism used to continue sampling during descent by parachute is described

  11. Understanding Citizenship, Understanding Social Media? The effects of digital media on citizenship understanding and political participation

    DEFF Research Database (Denmark)

    Ohme, Jakob; Albæk, Erik

    Is there a connection between increased use of digital media and changing patterns of political participation? This study tests how use of online media for different purposes (social interaction, creative expression, online news use, social media news use) is related to three types of political...... participation. It examines whether mobilizing effects are partly indirect due to different understandings of citizenship (dutiful, optional, individual, collective) that may be fostered by digital media use. The study is based on a survey of a sample of the Danish population (n=1322), including data from two...... online survey waves and a smartphone-based media diary that documents respondents’ social media use. Results indicate support for a new pathway to participation, but the relationship depends on whether citizens are socialized in a digital media environment....

  12. Press releases — the new trend in science communication

    DEFF Research Database (Denmark)

    Autzen, Charlotte

    2014-01-01

    Scientific institutions have for a long time known the importance of framing and owning stories about science They also know the effective way of communicating science in a press release This is part of the institution’s public relations. Enhanced competition among research institutions has led...... to a buildup of communicative competences and professionalization of public relations inside the institutions and the press release has become an integrated part of science communication from these institutions. Changing working conditions in the media, where fewer people have to publish more, have made press...... releases from trustworthy scientific institutions into free and easily copied content for the editors. In this commentary I investigate and discuss the communicative ecosystem of the university press release. I especially take a close look at the role of the critical and independent science journalist...

  13. Determination of uranium isotopes in environmental samples by anion exchange in sulfuric and hydrochloric acid media

    International Nuclear Information System (INIS)

    Popov, L.

    2016-01-01

    Method for determination of uranium isotopes in various environmental samples is presented. The major advantages of the method are the low cost of the analysis, high radiochemical yields and good decontamination factors from the matrix elements, natural and man-made radionuclides. The separation and purification of uranium is attained by adsorption with strong base anion exchange resin in sulfuric and hydrochloric acid media. Uranium is electrodeposited on a stainless steel disk and measured by alpha spectrometry. The analytical method has been applied for the determination of concentrations of uranium isotopes in mineral, spring and tap waters from Bulgaria. The analytical quality was checked by analyzing reference materials. - Highlights: • The method allows cost-effective determination of U isotopes. • High amounts of environmental samples can be analyzed. • High chemical yields, energy resolution and decontamination factors were achieved. • Uranium isotope concentrations in mineral waters from Bulgaria are presented.

  14. Remedial Investigation of Hanford Site Releases to the Columbia River - 13603

    Energy Technology Data Exchange (ETDEWEB)

    Lerch, J.A.; Hulstrom, L.C. [Washington Closure Hanford, LLC, Richland, Washington 99354 (United States); Sands, J.P. [U.S Department of Energy, Richland Operations Office, Richland, Washington 99352 (United States)

    2013-07-01

    In south-central Washington State, the Columbia River flows through the U.S. Department of Energy Hanford Site. A primary objective of the Hanford Site cleanup mission is protection of the Columbia River, through remediation of contaminated soil and groundwater that resulted from its weapons production mission. Within the Columbia River system, surface water, sediment, and biota samples related to potential Hanford Site hazardous substance releases have been collected since the start of Hanford operations. The impacts from release of Hanford Site radioactive substances to the Columbia River in areas upstream, within, and downstream of the Hanford Site boundary have been previously investigated as mandated by the U.S. Department of Energy requirements under the Atomic Energy Act. The Remedial Investigation Work Plan for Hanford Site Releases to the Columbia River [1] was issued in 2008 to initiate assessment of the impacts under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 [2]. The work plan established a phased approach to characterize contaminants, assess current risks, and determine whether or not there is a need for any cleanup actions. Field investigation activities over a 120-mile stretch of the Columbia River began in October 2008 and were completed in 2010. Sampled media included surface water, pore water, surface and core sediment, island soil, and fish (carp, walleye, whitefish, sucker, small-mouth bass, and sturgeon). Information and sample results from the field investigation were used to characterize current conditions within the Columbia River and assess whether current conditions posed a risk to ecological or human receptors that would merit additional study or response actions under CERCLA. The human health and ecological risk assessments are documented in reports that were published in 2012 [3, 4]. Conclusions from the risk assessment reports are being summarized and integrated with remedial investigation

  15. The Investigation of Mobbing Events Taking Place at Higher Education Institutions in Turkey Considering the Reflections on Media

    Directory of Open Access Journals (Sweden)

    Çubukçu Zühal

    2015-08-01

    Full Text Available The business-life related competition established in modern communities has also brought about some other problems. The attacks and intimidation attempts have introduced the term of “mobbing” which is defined as regular and continuous psychological violence faced by people always trying to produce and win from those who they work with. The term of “mobbing” has recently become a popular academic issue which has been sophisticatedly handled in relevant literature. Mobbing is defined as the act of continuous and systematic intimidation purposefully performed by either some employees or employers on some employees through emotional violence. As mobbing is considered to be significant for both corporate and employee, the starting point of this study was to investigate how mobbing acts are reflected on newspapers as they are mass communication means. One of the most important means of media is print media. Print media is the first means of media when mentioned about media. Newspapers are means through which people are always kept up to date about the latest news in civilized societies. With this regard, the most basic purpose of this study is to investigate the news about the mobbing events experienced in higher education system under the light of national policy documents and reports. The study was carried out based on a qualitative approach. The news released in print media was chosen purposefully as print media means report news in a detailed way, have an evidential value and can be read again on demand. The research group in this study consists of the mobbing news released on Hurriyet, Sabah and Zaman which are newspapers published in Turkey between the years of 2009-2013. These newspapers were purposefully chosen based on criterion sampling method. The most basic understanding underlying this sampling method is to study on all cases which meet the standards set prior to the start of the study. The newspapers mentioned above were chosen

  16. Effective media models for unsaturated fractured rock: A field experiment

    International Nuclear Information System (INIS)

    Nicholl, M.J.; Glass, R.J.

    1995-01-01

    A thick unsaturated rock mass at Yucca Mountain is currently under consideration as a potential repository site for disposal of high level radioactive waste. In accordance with standard industry and scientific practices, abstract numerical models will be used to evaluate the potential for radionuclide release through the groundwater system. At this time, currently available conceptual models used to develop effective media properties are based primarily on simplistic considerations. The work presented here is part of an integrated effort to develop effective media models at the intermediate block scale (approximately 8-125m) through a combination of physical observations, numerical simulations and theoretical considerations. A multi-purpose field experiment designed and conducted as part of this integrated effort is described. Specific goals of this experimental investigation were to: (1) obtain fracture network data from Topopah Spring Tuff for use in block scale simulations; (2) identity positions of the network conducting flow under three different boundary conditions; (3) visualize preferential flow paths and small-scale flow structures; (4) collect samples for subsequent hydraulic testing and use in block-scale simulations; and (5) demonstrate the ability of Electrical Resistance Tomography (ERT) to delineate fluid distribution within fractured rock

  17. Municipal Communication Strategies and Ethnic Media: A Settlement Service in Disguise

    Directory of Open Access Journals (Sweden)

    April Lindgren

    2015-12-01

    Full Text Available The Canadian Federation of Municipalities has declared cities as the “unofficial welcome wagon” for new Canadians. Research suggests, however, that they embrace settlement and integration policies to varying degrees. While scholarly examinations of municipal policies include analyses of corporate communications strategies, efforts by city governments to reach residents through ethnocultural news media have received little attention. To address that gap, this study investigates why the suburban community of Brampton, Canada adopted one of the most proactive ethnic media strategies in the country in 2015 when, just a decade earlier, it was for the most part unresponsive to the needs of its burgeoning immigrant population. As a starting point, the case study uses the determinants of municipal responsiveness identified by Kristin R. Good (2009 in Municipalities and Multiculturalism: The Politics of Immigration in Toronto and Vancouver. Employing a mixed methods approach, it concludes that rapid demographic change, the emergence of an activist political leadership, and efforts to reduce friction between newcomers and other residents influenced Brampton’s communications policy over time. The case study identifies challenges associated with adopting an ethnic media strategy, including issues related to translation and the relative lack of sophistication of some ethnic media outlets. Furthermore, it demonstrates that reaching out to ethnocultural communities via ethnic media requires more than just distributing news releases in English. Translation of these releases has the potential to increase municipal news coverage in ethnic media, the paper suggests, if only because it makes it easier for smaller news organizations to report on such matters.

  18. Release of volatile mercury from vascular plants

    Science.gov (United States)

    Siegel, S. M.; Puerner, N. J.; Speitel, T. W.

    1974-01-01

    Volatile, organic solvent soluble mercury has been found in leaves and seeds of several angiosperms. Leaves of garlic vine, avocado, and haole-koa release mercury in volatile form rapidly at room temperature. In garlic vine, the most active release is temperature dependent, but does not parallel the vapor-pressure temperature relationship for mercury. Mercury can be trapped in nitric-perchloric acid digestion fluid, or n-hexane, but is lost from the hexane unless the acid mixture is present. Seeds of haole-koa also contain extractable mercury but volatility declines in the series n-hexane (90%), methanol (50%), water (10%). This suggests that reduced volatility may accompany solvolysis in the more polar media.

  19. Factors associated with online media attention to research: a cohort study of articles evaluating cancer treatments.

    Science.gov (United States)

    Haneef, Romana; Ravaud, Philippe; Baron, Gabriel; Ghosn, Lina; Boutron, Isabelle

    2017-01-01

    New metrics have been developed to assess the impact of research and provide an indication of online media attention and data dissemination. We aimed to describe online media attention of articles evaluating cancer treatments and identify the factors associated with high online media attention. We systematically searched MEDLINE via PubMed on March 1, 2015 for articles published during the first 6 months of 2014 in oncology and medical journals with a diverse range of impact factors, from 3.9 to 54.4, and selected a sample of articles evaluating a cancer treatment regardless of study design. Altmetric Explorer was used to identify online media attention of selected articles. The primary outcome was media attention an article received online as measured by Altmetric score (i.e., number of mentions in online news outlets, science blogs and social media). Regression analysis was performed to investigate the factors associated with high media attention, and regression coefficients represent the logarithm of ratio of mean (RoM) values of Altmetric score per unit change in the covariate. Among 792 articles, 218 (27.5%) received no online media attention (Altmetric score = 0). The median [Q1-Q3] Altmetric score was 2.0 [0.0-8.0], range 0.0-428.0. On multivariate analysis, factors associated with high Altmetric score were presence of a press release (RoM = 10.14, 95%CI [4.91-20.96]), open access to the article (RoM = 1.48, 95%CI [1.02-2.16]), and journal impact factor (RoM = 1.10, 95%CI [1.07-1.12]. As compared with observational studies, systematic reviews were not associated with high Altmetric score (RoM = 1.46, 95%CI [0.74-2.86]; P  = 0.27), nor were RCTs (RoM = 0.65, 95%CI [0.41-1.02]; P  = 0.059) and phase I/II non-RCTs (RoM = 0.58, 95%CI [0.33-1.05]; P  = 0.07). The articles with abstract conclusions favouring study treatments were not associated with high Altmetric score (RoM = 0.97, 95%CI [0.60-1.58]; P  = 0

  20. Social Media in Virtual Marketing

    OpenAIRE

    Jalees, Tariq; Tariq, Huma; Zaman, Syed Imran; Alam Kazmi, Syed Hasnain

    2015-01-01

    Social media usage in the world and especially in Pakistan has a high growth due to which it (social media) has a potential of becoming an effective marketing tool. Despite its comparatively low cost and significance, marketers are not effectively utilizing social media. Thus the aim of this study is to measure the influence (effect) of four social variables: social capital, trust, homophily and interpersonal influence on electronic word of mouth (eWOM) communication. The sample size for the stu...

  1. 21 CFR 660.6 - Samples; protocols; official release.

    Science.gov (United States)

    2010-04-01

    ... product iodinated with 125I means a sample from each lot of diagnostic test kits in a finished package... manufacturer has satisfactorily completed all tests on the samples: (i) One sample until written notification... of this section, a sample of product not iodinated with 125I means a sample from each filling of each...

  2. Social Media Analyses for Social Measurement

    Science.gov (United States)

    Schober, Michael F.; Pasek, Josh; Guggenheim, Lauren; Lampe, Cliff; Conrad, Frederick G.

    2016-01-01

    Demonstrations that analyses of social media content can align with measurement from sample surveys have raised the question of whether survey research can be supplemented or even replaced with less costly and burdensome data mining of already-existing or “found” social media content. But just how trustworthy such measurement can be—say, to replace official statistics—is unknown. Survey researchers and data scientists approach key questions from starting assumptions and analytic traditions that differ on, for example, the need for representative samples drawn from frames that fully cover the population. New conversations between these scholarly communities are needed to understand the potential points of alignment and non-alignment. Across these approaches, there are major differences in (a) how participants (survey respondents and social media posters) understand the activity they are engaged in; (b) the nature of the data produced by survey responses and social media posts, and the inferences that are legitimate given the data; and (c) practical and ethical considerations surrounding the use of the data. Estimates are likely to align to differing degrees depending on the research topic and the populations under consideration, the particular features of the surveys and social media sites involved, and the analytic techniques for extracting opinions and experiences from social media. Traditional population coverage may not be required for social media content to effectively predict social phenomena to the extent that social media content distills or summarizes broader conversations that are also measured by surveys. PMID:27257310

  3. Social Media Analyses for Social Measurement.

    Science.gov (United States)

    Schober, Michael F; Pasek, Josh; Guggenheim, Lauren; Lampe, Cliff; Conrad, Frederick G

    2016-01-01

    Demonstrations that analyses of social media content can align with measurement from sample surveys have raised the question of whether survey research can be supplemented or even replaced with less costly and burdensome data mining of already-existing or "found" social media content. But just how trustworthy such measurement can be-say, to replace official statistics-is unknown. Survey researchers and data scientists approach key questions from starting assumptions and analytic traditions that differ on, for example, the need for representative samples drawn from frames that fully cover the population. New conversations between these scholarly communities are needed to understand the potential points of alignment and non-alignment. Across these approaches, there are major differences in (a) how participants (survey respondents and social media posters) understand the activity they are engaged in; (b) the nature of the data produced by survey responses and social media posts, and the inferences that are legitimate given the data; and (c) practical and ethical considerations surrounding the use of the data. Estimates are likely to align to differing degrees depending on the research topic and the populations under consideration, the particular features of the surveys and social media sites involved, and the analytic techniques for extracting opinions and experiences from social media. Traditional population coverage may not be required for social media content to effectively predict social phenomena to the extent that social media content distills or summarizes broader conversations that are also measured by surveys.

  4. The Role of Social Media User Experience as a Mediator for Understanding Social Media User Behavior in Indonesia’s Museum Industry: Literature Review

    Science.gov (United States)

    Sundjaja, A. M.; LumanGaol, F.; Budiarti, T.; Abbas, B. S.; Abdinagoro, S. B.; Ongowarsito, H.

    2017-01-01

    Social media has changed the interaction between the customer and the business, social media has proven to provide new opportunities in facilitating access to information, efficiency and ease of interaction between customers and businesses that are distributed geographically dispersed. Ease of interaction to improve access to information about products, services, and prices have proven to have a positive impact for consumers. The purpose of this article is to develop a conceptual model to test the effect of user motivation, user expectations, and online community involvement to the intention of behavior that is mediated by the use of social media museum experience. This article is a literature study on exploration of social media user experiences museum in Indonesia. Authors searched and examined 85 articles from google scholar with the following keywords: motivation, expectations, online communities, user experience, social media, Technology Acceptance Model, Experiential Marketing, Uses and Gratification Theory. Proposed data collection techniques are literature study, survey and observation. The sample used in this research is 400 respondents of social media users that follow the social media managed by Indonesia’s museum. The sampling technique are systematic sampling. We use Structural Equation Model with AMOS for analyze the data.

  5. Chromogenic media for urine cultures can be cost-effective

    Directory of Open Access Journals (Sweden)

    Matjaž J. Retelj

    2007-03-01

    Full Text Available Background: Chromogenic media for diagnostic urinary bacteriology have several advantages over traditional media, such as cysteine-lactose-electrolyte deficient (CLED medium. Chromogenic media allow for easier recognition of mixed growth, save time, reduce workload and provide higher detection rates. However, the cost of chromogenic media is significantly higher compared to CLED and performance of chromogenic media varies depending on the manufacturer. In the present study, performance, turn-around time and cost of Uriselect4 chromogenic medium was compared to CLED.Methods: For performance analysis, 351 midstream urine (MSU samples from September 2005 to December 2005 were directly plated in parallel on Uriselect4 and CLED agar using the calibrated loop technique. Isolates on Uriselect4 were presumptively identified according to the product insert. For cost-effectiveness analysis, we included 1,972 consecutive MSU samples from May 2005 to July 2006. We compared the cost of required materials as well as technologists’ or specialists’ time for each medium examined.Results: No significant differences were found between the isolation rates of urinary pathogens on the studied media. The procedure using chromogenic media for uropathogens is slightly cheaper than the procedure using CLED, considering the proportion of bacteriuria positive samples (50.5 % and the distribution of taxa among isolates (namely Escherichia coli with 59.6 % observed in our laboratory. At the current isolation proportion in MSU samples processed in our laboratory, the average time to reporting results could be decreased by 0.3 days.Conclusions: Use of chromogenic media for urine investigations offers multiple advantages without increasing costs compared to procedures using CLED.

  6. Hypoxic enhancement of exosome release by breast cancer cells

    International Nuclear Information System (INIS)

    King, Hamish W; Michael, Michael Z; Gleadle, Jonathan M

    2012-01-01

    Exosomes are nanovesicles secreted by tumour cells which have roles in paracrine signalling during tumour progression, including tumour-stromal interactions, activation of proliferative pathways and bestowing immunosuppression. Hypoxia is an important feature of solid tumours which promotes tumour progression, angiogenesis and metastasis, potentially through exosome-mediated signalling. Breast cancer cell lines were cultured under either moderate (1% O 2 ) or severe (0.1% O 2 ) hypoxia. Exosomes were isolated from conditioned media and quantitated by nanoparticle tracking analysis (NTA) and immunoblotting for the exosomal protein CD63 in order to assess the impact of hypoxia on exosome release. Hypoxic exosome fractions were assayed for miR-210 by real-time reverse transcription polymerase chain reaction and normalised to exogenous and endogenous control genes. Statistical significance was determined using the Student T test with a P value of < 0.05 considered significant. Exposure of three different breast cancer cell lines to moderate (1% O 2 ) and severe (0.1% O 2 ) hypoxia resulted in significant increases in the number of exosomes present in the conditioned media as determined by NTA and CD63 immunoblotting. Activation of hypoxic signalling by dimethyloxalylglycine, a hypoxia-inducible factor (HIF) hydroxylase inhibitor, resulted in significant increase in exosome release. Transfection of cells with HIF-1α siRNA prior to hypoxic exposure prevented the enhancement of exosome release by hypoxia. The hypoxically regulated miR-210 was identified to be present at elevated levels in hypoxic exosome fractions. These data provide evidence that hypoxia promotes the release of exosomes by breast cancer cells, and that this hypoxic response may be mediated by HIF-1α. Given an emerging role for tumour cell-derived exosomes in tumour progression, this has significant implications for understanding the hypoxic tumour phenotype, whereby hypoxic cancer cells may release

  7. The autocrine role of tryptase in pressure overload-induced mast cell activation, chymase release and cardiac fibrosis

    Directory of Open Access Journals (Sweden)

    Jianping Li

    2016-03-01

    Results and conclusion: The results indicate the presence of PAR-2 on MCs and that tryptase inhibition and nedocromil prevented TAC-induced fibrosis and increases in MC density, activation, and chymase release. Tryptase also significantly increased chymase concentration in ventricular slice culture media, which was prevented by the tryptase inhibitor. Hydroxyproline concentration in culture media was significantly increased with tryptase incubation as compared to the control group and the tryptase group incubated with nafamostat mesilate or chymostatin. We conclude that tryptase contributes to TAC-induced cardiac fibrosis primarily via activation of MCs and the amplified release of chymase.

  8. Reciprocal influence? Investigating implicit frames in press releases and financial newspaper coverage during the German banking crisis

    NARCIS (Netherlands)

    Strauß, N.; Vliegenthart, R.

    This study investigates the interrelation of implicit frames in press releases by the two largest German banks (Deutsche Bank, Commerzbank) and the German financial media from 2007 until 2013. Findings suggest that an increase in the salience of certain frames in press releases by German banks

  9. Effective media reporting of sea level rise projections: 1989-2009

    International Nuclear Information System (INIS)

    Rick, U K; Boykoff, M T; Pielke, R A Jr

    2011-01-01

    In the mass media, sea level rise is commonly associated with the impacts of climate change due to increasing atmospheric greenhouse gases. As this issue garners ongoing international policy attention, segments of the scientific community have expressed unease about how this has been covered by mass media. Therefore, this study examines how sea level rise projections-in IPCC Assessment Reports and a sample of the scientific literature-have been represented in seven prominent United States (US) and United Kingdom (UK) newspapers over the past two decades. The research found that-with few exceptions-journalists have accurately portrayed scientific research on sea level rise projections to 2100. Moreover, while coverage has predictably increased in the past 20 years, journalists have paid particular attention to the issue in years when an IPCC report is released or when major international negotiations take place, rather than when direct research is completed and specific projections are published. We reason that the combination of these factors has contributed to a perceived problem in the sea level rise reporting by the scientific community, although systematic empirical research shows none. In this contemporary high-stakes, high-profile and highly politicized arena of climate science and policy interactions, such results mark a particular bright spot in media representations of climate change. These findings can also contribute to more measured considerations of climate impacts and policy action at a critical juncture of international negotiations and everyday decision-making associated with the causes and consequences of climate change.

  10. The Politics of PISA: The Media, Policy and Public Responses in Norway and England

    Science.gov (United States)

    Hopfenbeck, Therese N.; Görgen, Kristine

    2017-01-01

    Using the PISA 2015 releases in Norway and England, this article explores how PISA has been presented in the media and how the policy level has responded to the results. England will be used as an example for comparison. The article presents early media responses from the 20 most circulated daily newspapers in the two countries and discusses them…

  11. Predicting release and transport of pesticides from a granular formulation during unsaturated diffusion in porous media

    DEFF Research Database (Denmark)

    Paradelo Pérez, Marcos; Soto-Gómez, Diego; Pérez-Rodrígez, Paula

    2014-01-01

    The release and transport of active ingredients (AIs) from controlled-release formulations (CRFs) have potential to reduce groundwater pesticide pollution. These formulations have a major effect on the release rate and subsequent transport to groundwater. Therefore the influence of CRFs should be...

  12. Interaction between fed and gastric media (ensure Plus) and different hypromellose based caffeine controlled release tablets; comparison and mechanistic study of caffeine release in fed and fasted media versus water using USP dissolution apparatus 3

    DEFF Research Database (Denmark)

    Franek, Frans; Holm, Per; Larsen, Frank

    2014-01-01

    , which decreases erosion rate in 100 mPa s viscosity tablets, swelling in 15,000 mPa s viscosity tablets and caffeine release from both tablets. This observed interaction between Ensure Plus® and the HPMC tablets may translate into decreased drug release rate in the fed stomach, which may decrease...... using factorial designed experiments. Furthermore, the mechanism of release in Ensure Plus®, a nutrition drink similar in composition to the FDA standard meal, was investigated by studying tablet swelling using texture analysis. Altering dip speed has negligible effect on release and erosion rates...... the amount of drug available for absorption in the small intestine and thus reduce systemic drug exposure and maximum plasma concentration....

  13. Molecularly Imprinted Polymers for 5-Fluorouracil Release in Biological Fluids

    Directory of Open Access Journals (Sweden)

    Franco Alhaique

    2007-04-01

    Full Text Available The aim of this work was to investigate the possibility of employing Molecularly Imprinted Polymers (MIPs as a controlled release device for 5-fluorouracil (5-FU in biological fluids, especially gastrointestinal ones, compared to Non Imprinted Polymers (NIPs. MIPs were synthesized using methacrylic acid (MAA as functional monomer and ethylene glycol dimethacrylate (EGDMA as crosslinking agent. The capacity of the polymer to recognize and to bind the template selectively in both organic and aqueous media was evaluated. An in vitro release study was performed both in gastrointestinal and in plasma simulating fluids. The imprinted polymers bound much more 5-Fu than the corresponding non-imprinted ones and showed a controlled/sustained drug release, with MIPs release rate being indeed much more sustained than that obtained from NIPs. These polymers represent a potential valid system for drug delivery and this study indicates that the selective binding characteristic of molecularly imprinted polymers is promising for the preparation of novel controlled release drug dosage form.

  14. Post-sampling release of free fatty acids - effects of heat stabilization and methods of euthanasia.

    Science.gov (United States)

    Jernerén, Fredrik; Söderquist, Marcus; Karlsson, Oskar

    2015-01-01

    The field of lipid research has made progress and it is now possible to study the lipidome of cells and organelles. A basic requirement of a successful lipid study is adequate pre-analytical sample handling, as some lipids can be unstable and postmortem changes can cause substantial accumulation of free fatty acids (FFAs). The aim of the present study was to investigate the effects of conductive heat stabilization and euthanasia methods on FFA levels in the rat brain and liver using liquid chromatography tandem mass spectrometry. The analysis of brain homogenates clearly demonstrated phospholipase activity and time-dependent post-sampling changes in the lipid pool of snap frozen non-stabilized tissue. There was a significant increase in FFAs already at 2min, which continued over time. Heat stabilization was shown to be an efficient method to reduce phospholipase activity and ex vivo lipolysis. Post-sampling effects due to tissue thawing and sample preparation induced a massive release of FFAs (up to 3700%) from non-stabilized liver and brain tissues compared to heat stabilized tissue. Furthermore, the choice of euthanasia method significantly influenced the levels of FFAs in the brain. The FFAs were decreased by 15-44% in the group of animals euthanized by pentobarbital injection compared with CO2 inhalation or decapitation. Our results highlight the importance of considering euthanasia methods and pre-analytical treatment in lipid analysis, factors which may otherwise interfere with the outcome of the experiments. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. Invited commentary: recruiting for epidemiologic studies using social media.

    Science.gov (United States)

    Allsworth, Jenifer E

    2015-05-15

    Social media-based recruitment for epidemiologic studies has the potential to expand the demographic and geographic reach of investigators and identify potential participants more cost-effectively than traditional approaches. In fact, social media are particularly appealing for their ability to engage traditionally "hard-to-reach" populations, including young adults and low-income populations. Despite their great promise as a tool for epidemiologists, social media-based recruitment approaches do not currently compare favorably with gold-standard probability-based sampling approaches. Sparse data on the demographic characteristics of social media users, patterns of social media use, and appropriate sampling frames limit our ability to implement probability-based sampling strategies. In a well-conducted study, Harris et al. (Am J Epidemiol. 2015;181(10):737-746) examined the cost-effectiveness of social media-based recruitment (advertisements and promotion) in the Contraceptive Use, Pregnancy Intention, and Decisions (CUPID) Study, a cohort study of 3,799 young adult Australian women, and the approximate representativeness of the CUPID cohort. Implications for social media-based recruitment strategies for cohort assembly, data accuracy, implementation, and human subjects concerns are discussed. © The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  16. Tritium sample analyses in the Savannah River and associated waterways following the K-reactor release of December 1991

    International Nuclear Information System (INIS)

    Beals, D.M.; Dunn, D.L.; Hall, G.; Kantelo, M.V.

    1992-01-01

    An unplanned release of tritiated water occurred at K reactor on SRS between 22-December and 25-December 1991. This water moved down through the effluent canal, Pen Branch, Steel Creek and finally to the Savannah River. Samples were collected in the Savannah River and associated waterways over a period of a month. The Environmental Technology Section (ETS) of the Savannah River Laboratory performed liquid scintillation analyses to monitor the passage of the tritiated water from SRS to the Atlantic Ocean

  17. Release of β-galactosidase from poloxamine/α-cyclodextrin hydrogels

    Directory of Open Access Journals (Sweden)

    César A. Estévez

    2014-12-01

    Full Text Available All mammals lose their ability to produce lactase (β-galactosidase, the enzyme that cleaves lactose into galactose and glucose, after weaning. The prevalence of lactase deficiency (LD spans from 2 to 15% among northern Europeans, to nearly 100% among Asians. Following lactose consumption, people with LD often experience gastrointestinal symptoms such as abdominal pain, bowel distension, cramps and flatulence, or even systemic problems such as headache, loss of concentration and muscle pain. These symptoms vary depending on the amount of lactose ingested, type of food and degree of intolerance. Although those affected can avoid the uptake of dairy products, in doing so, they lose a readily available source of calcium and protein. In this work, gels obtained by complexation of Tetronic 90R4 with α-cyclodextrin loaded with β-galactosidase are proposed as a way to administer the enzyme immediately before or with the lactose-containing meal. Both molecules are biocompatible, can form gels in situ, and show sustained erosion kinetics in aqueous media. The complex was characterized by FTIR that evidenced an inclusion complex between the polyethylene oxide block and α-cyclodextrin. The release profiles of β-galactosidase from two different matrices (gels and tablets of the in situ hydrogels have been obtained. The influence of the percentage of Tetronic in media of different pH was evaluated. No differences were observed regarding the release rate from the gel matrices at pH 6 (t50 = 105 min. However, in the case of the tablets, the kinetics were faster and they released a greater amount of 90R4 (25%, t50 = 40–50 min. Also, the amount of enzyme released was higher for mixtures with 25% Tetronic. Using suitable mathematical models, the corresponding kinetic parameters have been calculated. In all cases, the release data fit quite well to the Peppas–Sahlin model equation, indicating that the release of β-galactosidase is governed by a

  18. Using Social Media to Involve the Public in Wildlife Research--The SNAMP Fisher Sock Collection Drive

    Science.gov (United States)

    Kocher, Susie; Lombardo, Anne; Sweitzer, Rick A.

    2013-01-01

    The University of California Cooperative Extension used social media to solicit donations to support research on the Pacific fisher, a rare forest-dwelling weasel, conducted by UC scientists. The social media campaign included blog and Facebook postings, news releases, and tweets requesting donations of single socks. Socks were donated from around…

  19. Do you use social media? A study into new nursing and midwifery graduates' uptake of social media.

    Science.gov (United States)

    Tuckett, Anthony; Turner, Catherine

    2016-04-01

    Social media use is expanding rapidly, so too is its use within hospitals and amongst healthcare professionals. This study describes the use of social media by Australian and New Zealand nursing and midwifery graduates of the Graduate e-Cohort study; there were 112 (93%) respondents from a 2014 sample of 121 nurses and midwives. Findings suggest that the professional peak body goal of using social media as a vehicle for professional education requires consideration of the social media platforms that are actually being used by new graduates. We recommend that work by the respective professions at both an undergraduate and graduate level needs to focus on the implications of social media use or policy and practice to ensure that everyone is aware of when and how to engage in social media platforms and what to do and how to behave when using social media. © 2015 John Wiley & Sons Australia, Ltd.

  20. Management Matters: The Library Media Specialist's Management Toolbox

    Science.gov (United States)

    Pappas, Marjorie L.

    2004-01-01

    Library media specialists need tools to help them manage the school library media program. The Internet includes a vast array of tools that a library media specialist might find useful. The websites and electronic resources included in this article are only a representative sample and future columns may explore additional tools. All the tools are…

  1. Media multitasking and behavioral measures of sustained attention.

    Science.gov (United States)

    Ralph, Brandon C W; Thomson, David R; Seli, Paul; Carriere, Jonathan S A; Smilek, Daniel

    2015-02-01

    In a series of four studies, self-reported media multitasking (using the media multitasking index; MMI) and general sustained-attention ability, through performance on three sustained-attention tasks: the metronome response task (MRT), the sustained-attention-to-response task (SART), and a vigilance task (here, a modified version of the SART). In Study 1, we found that higher reports of media multitasking were associated with increased response variability (i.e., poor performance) on the MRT. However, in Study 2, no association between reported media multitasking and performance on the SART was observed. These findings were replicated in Studies 3a and 3b, in which we again assessed the relation between media multitasking and performance on both the MRT and SART in two large online samples. Finally, in Study 4, using a large online sample, we tested whether media multitasking was associated with performance on a vigilance task. Although standard vigilance decrements were observed in both sensitivity (A') and response times, media multitasking was not associated with the size of these decrements, nor was media multitasking associated with overall performance, in terms of either sensitivity or response times. Taken together, the results of the studies reported here failed to demonstrate a relation between habitual engagement in media multitasking in everyday life and a general deficit in sustained-attention processes.

  2. Survey of the pharmacology of non-ionic X-ray contrast media

    International Nuclear Information System (INIS)

    Turnheim, K.

    1986-01-01

    The non-ionic X-ray contrast media metrizamide, iopamidol, iohexol, and iopromide do not bind calcium and are less hyperosmolar than the conventional ionic contrast media, for instance amidotrizoate (diatrizoate), iothalamte, or ioglicate. Hence the use of non-ionic contrast media is associated with less undesirable side-effects that are attributable to hypertonicity such as an increase in circulating plasma volume, decreased deformability of red blood cells, damage of vascular endothelium with consequent activation of blood coagulation, the complement system and fibrinolysis, increased release of bradykinin and histamine, cardiac arrhythimas, diuresis, vasodilation and decreased blood pressure, pain and heat sensation. Because of less dilution the quality of imaging is also better. According to the intravenous LD 50 in experimental animals the acute toxicity of non-ionic contrast media is lower than that of ionic media. With respect to contrast quality and the rate of side-effects tha various non-ionic contrast media appear to be equivalent. Despite their higher price and higher viscosity it is probable that the non-ionic contrast media will replace the classical ionic media, especially in angio- and myelography. (Author)

  3. The Amount of Media and Information Literacy Among Isfahan University of Medical Sciences' Students Using Iranian Media and Information Literacy Questionnaire (IMILQ).

    Science.gov (United States)

    Ashrafi-Rizi, Hasan; Ramezani, Amir; Koupaei, Hamed Aghajani; Kazempour, Zahra

    2014-12-01

    Media and Information literacy (MIL) enables people to interpret and make informed judgments as users of information and media, as well as to become skillful creators and producers of information and media messages in their own right. The purpose of this research was to determine the amount of Media and Information Literacy among Isfahan University of Medical Sciences' students using Iranian Media and Information Literacy Questionnaire (IMILQ). This is an applied analytical survey research in which the data were collected by a researcher made questionnaire, provided based on specialists' viewpoints and valid scientific works. Its validity and reliability were confirmed by Library and Information Sciences specialists and Cronbach's alpha (r=0.89) respectively. Statistical population consisted of all students in Isfahan University of Medical Sciences (6000 cases) and the samples were 361. Sampling method was random stratified sampling. Data were analyzed by descriptive and inferential statistics. The findings showed that the mean level of Media and Information Literacy among Isfahan University of Medical Sciences' students was 3.34±0.444 (higher than average). The highest mean was promotion of scientific degree with 3.84±0.975 and the lowest mean was difficulties in starting research with 2.50±1.08. There was significant difference between educational degree, college type and family's income and amount of Media and Information Literacy. The results showed that the students didn't have enough skills in starting the research, defining the research subject as well as confining the research subject. In general, all students and education practitioners should pay special attention to factors affecting in improving Media and Information Literacy as a main capability in using printed and electronic media.

  4. Contact: Releasing the news

    Science.gov (United States)

    Pinotti, Roberto

    The problem of mass behavior after man's future contacts with other intelligences in the universe is not only a challenge for social scientists and political leaders all over the world, but also a cultural time bomb as well. In fact, since the impact of CETI (Contact with Extraterrestrial Intelligence) on human civilization, with its different cultures, might cause a serious socio-anthropological shock, a common and predetermined worldwide strategy is necessary in releasing the news after the contact, in order to keep possible manifestations of fear, panic and hysteria under control. An analysis of past studies in this field and of parallel historical situations as analogs suggests a definite "authority crisis" in the public as a direct consequence of an unexpected release of the news, involving a devastating "chain reaction" process (from both the psychological and sociological viewpoints) of anomie and maybe the collapse of today's society. The only way to prevent all this is to prepare the world's public opinion concerning contact before releasing the news, and to develop a long-term strategy through the combined efforts of scientists, political leaders, intelligence agencies and the mass media, in order to create the cultural conditions in which a confrontation with ETI won't affect mankind in a traumatic way. Definite roles and tasks in this multi-level model are suggested.

  5. RAVEN Beta Release

    International Nuclear Information System (INIS)

    Rabiti, Cristian; Alfonsi, Andrea; Cogliati, Joshua Joseph; Mandelli, Diego; Kinoshita, Robert Arthur; Wang, Congjian; Maljovec, Daniel Patrick; Talbot, Paul William

    2016-01-01

    This documents the release of the Risk Analysis Virtual Environment (RAVEN) code. A description of the RAVEN code is provided, and discussion of the release process for the M2LW-16IN0704045 milestone. The RAVEN code is a generic software framework to perform parametric and probabilistic analysis based on the response of complex system codes. RAVEN is capable of investigating the system response as well as the input space using Monte Carlo, Grid, or Latin Hyper Cube sampling schemes, but its strength is focused toward system feature discovery, such as limit surfaces, separating regions of the input space leading to system failure, using dynamic supervised learning techniques. RAVEN has now increased in maturity enough for the Beta 1.0 release.

  6. RAVEN Beta Release

    Energy Technology Data Exchange (ETDEWEB)

    Rabiti, Cristian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Alfonsi, Andrea [Idaho National Lab. (INL), Idaho Falls, ID (United States); Cogliati, Joshua Joseph [Idaho National Lab. (INL), Idaho Falls, ID (United States); Mandelli, Diego [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kinoshita, Robert Arthur [Idaho National Lab. (INL), Idaho Falls, ID (United States); Wang, Congjian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Maljovec, Daniel Patrick [Idaho National Lab. (INL), Idaho Falls, ID (United States); Talbot, Paul William [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-02-01

    This documents the release of the Risk Analysis Virtual Environment (RAVEN) code. A description of the RAVEN code is provided, and discussion of the release process for the M2LW-16IN0704045 milestone. The RAVEN code is a generic software framework to perform parametric and probabilistic analysis based on the response of complex system codes. RAVEN is capable of investigating the system response as well as the input space using Monte Carlo, Grid, or Latin Hyper Cube sampling schemes, but its strength is focused toward system feature discovery, such as limit surfaces, separating regions of the input space leading to system failure, using dynamic supervised learning techniques. RAVEN has now increased in maturity enough for the Beta 1.0 release.

  7. Islamic Images and Terminology Used in the Western Media

    Directory of Open Access Journals (Sweden)

    Bashy Quraishy

    2005-06-01

    Full Text Available Most societies in Western World has formulated a premature assumptions toward Islam due to the negative depictions of Islamic world doing by Western media which focused mainly on the issues of terrorism, intolerance, poverty, conflicts, fanaticism, horrible disease, low life qualities among Islamic countries, backwardness and lack of progress. This article explores and describes some statements made by Western media (as well as Western journalists, along with events as the setting of such comments. In order to overcome such situations, media monitoring must be professional and constant. Those who concern with the misleading information toward Islam must provide clear, short, and well-written press releases at regular intervals. Another suggestion is by drawing attention of ethnic youth toward journalism as noble profession and good trade.

  8. Helium release from radioisotope heat sources

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, D.E.; Early, J.W.; Starzynski, J.S.; Land, C.C.

    1984-05-01

    Diffusion of helium in /sup 238/PuO/sub 2/ fuel was characterized as a function of the heating rate and the fuel microstructure. The samples were thermally ramped in an induction furnace and the helium release rates measured with an automated mass spectrometer. The diffusion constants and activation energies were obtained from the data using a simple diffusion model. The release rates of helium were correlated with the fuel microstructure by metallographic examination of fuel samples. The release mechanism consists of four regimes, which are dependent upon the temperature. Initially, the release is controlled by movement of point defects combined with trapping along grain boundaries. This regime is followed by a process dominated by formation and growth of helium bubbles along grain boundaries. The third regime involves volume diffusion controlled by movement of oxygen vacancies. Finally, the release at the highest temperatures follows the diffusion rate of intragranular bubbles. The tendency for helium to be trapped within the grain boundaries diminishes with small grain sizes, slow thermal pulses, and older fuel.

  9. Validation of software releases for CMS

    International Nuclear Information System (INIS)

    Gutsche, Oliver

    2010-01-01

    The CMS software stack currently consists of more than 2 Million lines of code developed by over 250 authors with a new version being released every week. CMS has setup a validation process for quality assurance which enables the developers to compare the performance of a release to previous releases and references. The validation process provides the developers with reconstructed datasets of real data and MC samples. The samples span the whole range of detector effects and important physics signatures to benchmark the performance of the software. They are used to investigate interdependency effects of all CMS software components and to find and fix bugs. The release validation process described here is an integral part of CMS software development and contributes significantly to ensure stable production and analysis. It represents a sizable contribution to the overall MC production of CMS. Its success emphasizes the importance of a streamlined release validation process for projects with a large code basis and significant number of developers and can function as a model for future projects.

  10. Helium release from radioisotope heat sources

    International Nuclear Information System (INIS)

    Peterson, D.E.; Early, J.W.; Starzynski, J.S.; Land, C.C.

    1984-05-01

    Diffusion of helium in 238 PuO 2 fuel was characterized as a function of the heating rate and the fuel microstructure. The samples were thermally ramped in an induction furnace and the helium release rates measured with an automated mass spectrometer. The diffusion constants and activation energies were obtained from the data using a simple diffusion model. The release rates of helium were correlated with the fuel microstructure by metallographic examination of fuel samples. The release mechanism consists of four regimes, which are dependent upon the temperature. Initially, the release is controlled by movement of point defects combined with trapping along grain boundaries. This regime is followed by a process dominated by formation and growth of helium bubbles along grain boundaries. The third regime involves volume diffusion controlled by movement of oxygen vacancies. Finally, the release at the highest temperatures follows the diffusion rate of intragranular bubbles. The tendency for helium to be trapped within the grain boundaries diminishes with small grain sizes, slow thermal pulses, and older fuel

  11. Food Blogger Instagram: Promotion Through Social Media

    Directory of Open Access Journals (Sweden)

    M. Fariz Syahbani

    2017-04-01

    ABSTRACT Do promotions through food blogger account is the way that is currently being sought after by the culinary business operators to introduce their restaurant. Bloggers have a significant impact of people searching for information through social sites before making a purchase. In other words, the food blogger become a benchmark for people in considering whether or not a restaurant worth visiting. This research aims to determine of promotion through food blogger on social media instagram towards purchase intention of college student in Bandung. This research is a quantitative research. The method used is descriptive - causal. The sampling technique used is a non-probability sample of the type of incidental sampling. The data collection was distributed with questionnaires to 400 respondents who are collage students in Bandung was using instagram and recognizing the phenomenon of food bloggers as media promotion. Data analysis technique used is multiple linear regression analysis. The research results, food blogger promotion through social media on instagram be in good category. Purchase intention of college student at Bandung in good categories. Promotion through food blogger on social media instagram partial effect consisting of context, communication, collaboration and connection to the buying interest of collage students in Bandung and simultaneously influence the buying interest of collage students in Bandung. From this study, it appears that through the instagram as an effective media campaign can provide an explanation and the message delivered effectively and efficiently for displaying a variety of contexts with good multimedia features. Keyword : Promotion, Social Media Marketing, Food Blogger, Purchase Intention

  12. Nanoscale Coloristic Pigments: Upper Limits on Releases from Pigmented Plastic during Environmental Aging, In Food Contact, and by Leaching.

    Science.gov (United States)

    Neubauer, Nicole; Scifo, Lorette; Navratilova, Jana; Gondikas, Andreas; Mackevica, Aiga; Borschneck, Daniel; Chaurand, Perrine; Vidal, Vladimir; Rose, Jerome; von der Kammer, Frank; Wohlleben, Wendel

    2017-10-17

    The life cycle of nanoscale pigments in plastics may cause environmental or human exposure by various release scenarios. We investigated spontaneous and induced release with mechanical stress during/after simulated sunlight and rain degradation of polyethylene (PE) with organic and inorganic pigments. Additionally, primary leaching in food contact and secondary leaching from nanocomposite fragments with an increased surface into environmental media was examined. Standardized protocols/methods for release sampling, detection, and characterization of release rate and form were applied: Transformation of the bulk material was analyzed by Scanning Electron Microscopy (SEM), X-ray-tomography and Fourier-Transform Infrared spectroscopy (FTIR); releases were quantified by Inductively Coupled Plasma Mass Spectrometry (ICP-MS), single-particle-ICP-MS (sp-ICP-MS), Transmission Electron Microscopy (TEM), Analytical Ultracentrifugation (AUC), and UV/Vis spectroscopy. In all scenarios, the detectable particulate releases were attributed primarily to contaminations from handling and machining of the plastics, and were not identified with the pigments, although the contamination of 4 mg/kg (Fe) was dwarfed by the intentional content of 5800 mg/kg (Fe as Fe 2 O 3 pigment). We observed modulations (which were at least partially preventable by UV stabilizers) when comparing as-produced and aged nanocomposites, but no significant increase of releases. Release of pigments was negligible within the experimental error for all investigated scenarios, with upper limits of 10 mg/m 2 or 1600 particles/mL. This is the first holistic confirmation that pigment nanomaterials remain strongly contained in a plastic that has low diffusion and high persistence such as the polyolefin High Density Polyethylene (HDPE).

  13. Simulated food effects on drug release from ethylcellulose: PVA-PEG graft copolymer-coated pellets.

    Science.gov (United States)

    Muschert, Susanne; Siepmann, Florence; Leclercq, Bruno; Carlin, Brian; Siepmann, Juergen

    2010-02-01

    Food effects might substantially alter drug release from oral controlled release dosage forms in vivo. The robustness of a novel type of controlled release film coating was investigated using various types of release media and two types of release apparatii. Importantly, none of the investigated conditions had a noteworthy impact on the release of freely water-soluble diltiazem HCl or slightly water-soluble theophylline from pellets coated with ethylcellulose containing small amounts of PVA-PEG graft copolymer. In particular, the presence of significant amounts of fats, carbohydrates, surfactants, bile salts, and calcium ions in the release medium did not alter drug release. Furthermore, changes in the pH and differences in the mechanical stress the dosage forms were exposed to did not affect drug release from the pellets. The investigated film coatings allowing for oral controlled drug delivery are highly robust in vitro and likely to be poorly sensitive to classical food effects in vivo.

  14. The intracellular uptake and protracted release of exogenous heparins by cultured endothelial cells

    International Nuclear Information System (INIS)

    Hiebert, L.M.; McDuffie, N.M.

    1989-01-01

    Heparins from bovine or porcine sources were fed in media for 48 hrs to cultured porcine aortic and human umbilical vein endothelial cells. Heparin was found in pericellular and cellular fractions after extraction by chemical methods and 125 I radiolabelled heparins were recovered when radiolabelled heparin was included in the feed. Even after washing and media changes heparin was detected in media and cell fractions up to 6 days post feeding. Metachromatic vacuoles within cells were demonstrated histologically up to 7 days post feeding after staining with toluidine blue. This is the first report of protracted internalization of exogenous heparin by cultured endothelial cells with concurrent prolonged release of the heparin to the media. This clearly demonstrates that the endothelium plays an important role in the distribution and metabolism of heparin

  15. EFEKTIVITAS MEDIA BOOKLET BRAILLE DALAM MENINGKATKAN PENGETAHUAN GIZI PADA ANAK TUNANETRA

    Directory of Open Access Journals (Sweden)

    Ellyza Ulya

    2014-10-01

    Full Text Available Berdasarkan studi pendahuluan pada 10 siswa tunanetra di Kota Semarang tahun ajaran 2012/2013 didapatkan 60% siswa memiliki pengetahuan gizi yang kurang baik. Selain itu pada dua sekolah dasar luar biasa di Kota Semarang, yaitu SDLB Negeri Semarang dan SDLB A Dria Adi belum tersedia media booklet gizi dengan huruf Braille. Penelitian ini bertujuan untuk efektivitas media booklet dengan huruf braille dalam meningkatkan pengetahuan gizi pada anak tunanetra di Kota Semarang. Jenis penelitian ini adalah pra eksperimen dengan pendekatan One Group Pretest-Posttest Design. Pengambilan sampel dilakukan secara non random (non probability sampling dengan teknik purposive sampling. Populasi dalam penelitian ini adalah seluruh siswa tunanetra di SDLB A Dria Adi dan SDLB Negeri Semarang. Sampel dalam penelitian ini berjumlah 15 siswa tunanetra. Hasil uji t test berpasangan diperoleh hasil signifikansi 0,000 berarti terdapat perbedaan yang bermakna antara selisih nilai pretest dan posttest. Maka didapatkan hasil bahwa media booklet dengan huruf braille efektif dalam meningkatkan pengetahuan gizi anak tunanetra di Kota Semarang. Berdasarkan hasil penelitian dapat disimpulkan bahwa media booklet dengan huruf braille efektif dalam meningkatkan pengetahuan gizi pada anak tunanetra di Kota Semarang. Saran dari peneliti kepada pihak sekolah yaitu media booklet braille dapat dijadikan pertimbangan dasar dalam pembuatan media penyuluhan gizi. Based on the pre study on 10 blind students in Semarang found 60% of students have a poor nutritional knowledge. SLB N Semarang and SLB A Dria Adi does not have nutrient media booklet in Braille. This study aims to effectiveness media booklet Braille in improving nutrition knowledge of blind children at Semarang City.The study was pre experiment with approaches One Group Pretest-Posttest Design. Sampling was done by non-random (non-probability sampling with purposive sampling technique. The population in this study are all blind

  16. Synthesis, characterization, and controlled release anticorrosion behavior of benzoate intercalated Zn-Al layered double hydroxides

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yi [Shandong Provincial Key Lab of Corrosion Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071 (China); Zhang, Dun, E-mail: zhangdun@qdio.ac.cn [Shandong Provincial Key Lab of Corrosion Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071 (China)

    2011-11-15

    Graphical abstract: The benzoate anion released from Zn-Al LDHs provides a more effective long-term protection against corrosion of Q235 carbon steel in 3.5% NaCl solution. Highlights: {yields} A benzoate anion corrosion inhibitor intercalated Zn-Al layered double hydroxides (LDHs) has been assembled by coprecipitation method. {yields} The kinetic simulation indicates that the ion-exchange one is responsible for the release process and the diffusion through particle is the rate limiting step. {yields} A significant reduction of the corrosion rate is observed when the LDH nanohybrid is present in the corrosive media. -- Abstract: Corrosion inhibitor-inorganic clay composite including benzoate anion intercalated Zn-Al layered double hydroxides (LDHs) are assembled by coprecipitation. Powder X-ray diffraction (XRD) and Fourier transform infrared (FT-IR) spectrum analyses indicate that the benzoate anion is successfully intercalated into the LDH interlayer and the benzene planes are vertically bilayer-positioned as a quasi-guest ion-pair form in the gallery space. Kinetic simulation for the release data, XRD and FT-IR analyses of samples recovered from the release medium indicate that ion-exchange is responsible for the release process and diffusion through the particle is also indicated to be the rate-limiting step. The anticorrosion capabilities of LDHs loaded with corrosion inhibitor toward Q235 carbon steel are analyzed by polarization curve and electrochemical impedance spectroscopy methods. Significant reduction of corrosion rate is observed when the LDH nanohybrid is present in the corrosive medium. This hybrid material may potentially be applied as a nanocontainer in self-healing coatings.

  17. Analysis of drug effects on neurotransmitter release

    International Nuclear Information System (INIS)

    Rowell, P.; Garner, A.

    1986-01-01

    The release of neurotransmitter is routinely studied in a superfusion system in which serial samples are collected and the effects of drugs or other treatments on the amount of material in the superfusate is determined. With frequent sampling interval, this procedure provides a mechanism for dynamically characterizing the release process itself. Using automated data collection in conjunction with polyexponential computer analysis, the equation which describes the release process in each experiment is determined. Analysis of the data during the nontreated phase of the experiment allows an internal control to be used for accurately assessing any changes in neurotransmitter release which may occur during a subsequent treatment phase. The use of internal controls greatly improves the signal to noise ratio and allows determinations of very low concentrations of drugs on small amounts of tissue to be made. In this presentation, the effects of 10 μM nicotine on 3 H-dopamine release in rat nucleus accumbens is described. The time course, potency and efficacy of the drug treatment is characterized using this system. Determinations of the exponential order of the release as well as the rate constants allow one to study the mechanism of the release process. A description of 3 H-dopamine release in normal as well as Ca ++ -free medium is presented

  18. Monolith Chromatography as Sample Preparation Step in Virome Studies of Water Samples.

    Science.gov (United States)

    Gutiérrez-Aguirre, Ion; Kutnjak, Denis; Rački, Nejc; Rupar, Matevž; Ravnikar, Maja

    2018-01-01

    Viruses exist in aquatic media and many of them use this media as transmission route. Next-generation sequencing (NGS) technologies have opened new doors in virus research, allowing also to reveal a hidden diversity of viral species in aquatic environments. Not surprisingly, many of the newly discovered viruses are found in environmental fresh and marine waters. One of the problems in virome research can be the low amount of viral nucleic acids present in the sample in contrast to the background ones (host, eukaryotic, prokaryotic, environmental). Therefore, virus enrichment prior to NGS is necessary in many cases. In water samples, an added problem resides in the low concentration of viruses typically present in aquatic media. Different concentration strategies have been used to overcome such limitations. CIM monoliths are a new generation of chromatographic supports that due to their particular structural characteristics are very efficient in concentration and purification of viruses. In this chapter, we describe the use of CIM monolithic chromatography for sample preparation step in NGS studies targeting viruses in fresh or marine water. The step-by-step protocol will include a case study where CIM concentration was used to study the virome of a wastewater sample using NGS.

  19. Media Education Initiatives by Media Organizations: The Uses of Media Literacy in Hong Kong Media

    Science.gov (United States)

    Chu, Donna; Lee, Alice Y. L.

    2014-01-01

    As more media organizations have engaged in media education, this paper investigates the goals and practices of these activities. This article coins media education initiatives by media organizations with the term "media-organization media literac"y (MOML). Four MOML projects in Hong Kong were selected for examination. Built on critical…

  20. Examining Media Literacy Levels of Prospective Teachers

    Directory of Open Access Journals (Sweden)

    Taskın INAN

    2012-04-01

    Full Text Available As in many other countries, following the 2007-2008 education year when media literacy courses began to be included in the curricula, media literacy has become one of the discussion topics among educators and decision makers in Turkey. Discussion topics related to media literacy have included who is going to give the media literacy courses, what qualifications will be sought out in media literacy education teachers, what will be included in the media literacy curriculum in terms of its content, and at what level the media literacy course will be given. The current study which aims to examine media literacy levels of prospective teachers utilized thesurvey method. The sample of the study included prospective teachers (480 attending Elementary School Education, Social Studies Education and Turkish Language Education departments in the Education Faculty at the Dumlupinar University in the 2008-2009 education year. The results of the study showed that prospective teachers have a low level of reaction to media messages, do not educate people around enough about the effects of media, but make use of different sources of media to gain information, and are cognizant of media literacy.

  1. Examining media literacy levels of prospective teachers

    Directory of Open Access Journals (Sweden)

    Taşkın İnan

    2012-03-01

    Full Text Available As in many other countries, following the 2007-2008 education year when media literacy courses began to be included in the curricula, media literacy has become one of the discussion topics among educators and decision makers in Turkey. Discussion topics related to media literacy have included who is going to give the media literacy courses, what qualifications will be sought out in media literacy education teachers, what will be included in the media literacy curriculum in terms of its content, and at what level the media literacy course will be given. The current study which aims to examine media literacy levels of prospective teachers utilized the survey method. The sample of the study included prospective teachers (480 attending Elementary School Education, Social Studies Education and Turkish Language Education departments in the Education Faculty at the Dumlupinar University in the 2008-2009 education year. The results of the study showed that prospective teachers have a low level of reaction to media messages, do not educate people around enough about the effects of media, but make use of different sources of media to gain information, and are cognizant of media literacy.

  2. Evaluation of chemical stability of vitrification media for radioactive waste products

    International Nuclear Information System (INIS)

    Barkatt, A.; Simmons, J.H.; Macedo, P.B.

    1981-01-01

    Test methods and test results concerning the measurement of chemical durability of glass media proposed for nuclear waste fixation are described. In order to develop predictive models and risk calculations, the release rates of individual components are measured. The results are used to determine matrix dissolution rates, possible transport of components through the matrix, and chemical and physical corrosion mechanisms. Measurements on model borosilicate and high silica glass fixation media are reported and discussed in terms of layer formation, approach to steady state, interaction of polyvalent ions with the dealkalised layer, structural disintegration of the layer, and the effects of glass composition and of environmental conditions (temperature, leachant composition and pH, γ dose). The extrapolation of short term laboratory tests to long time storage conditions and the use of such extrapolation in predicting safe upper limits for the release rates of components of the glass are described. (author)

  3. Synthesis, recognition and evaluation of molecularly imprinted polymer nanoparticle using miniemulsion polymerization for controlled release and analysis of risperidone in human plasma samples

    International Nuclear Information System (INIS)

    Asadi, Ebadullah; Azodi-Deilami, Saman; Abdouss, Majid; Kordestani, Davood; Rahimi, Alireza; Asadi, Somayeh

    2014-01-01

    We prepared high selective imprinted nanoparticle polymers by a miniemulsion polymerization technique, using risperidone as the template, MAA as the functional monomers, and TRIM as the cross-linker in acetonitrile as solvent. The morphology of the nanoparticles determined by scanning electron microscopy (SEM) images and drug release, binding properties and dynamic light scattering (DLS) of molecularly imprinted polymers (MIPs) were studied. Controlled release of risperidone from nanoparticles was investigated through in 1% wt sodium dodecyl sulfate aqueous solution and by measuring the absorbance by HPLC-UV. The results showed that the imprinted nanoparticles exhibited a higher binding level and slower release rate than non-imprinted nanoparticles, which contributed to interaction of risperidone with imprinted cavities within nanoparticles. Furthermore, the results from HPLC showed good precision (5% for 50.0 µg L -1 ) and recoveries (between 86-91) using MIP from human plasma samples

  4. Social media use by orthodontic patients.

    Science.gov (United States)

    Henzell, M; Knight, A; Antoun, J S; Farella, M

    2013-12-01

    Internet-based social media sites have recently surged in popularity and are often used to share thoughts and seek support about health issues. The aim of this study was to investigate how orthodontic patients use Internet-based social media sites to share their treatment-related experiences and attitudes towards braces. A secondary objective was to investigate whether an online or mobile application would be considered helpful in improving co-operation with the use of orthodontic appliances. Patients visiting the orthodontic clinic at the University of Otago were asked to participate in a cross-sectional survey that sought details of their Internet-based social media use and their thoughts about the development of a reminder application. The sample comprised 130 orthodontic patients, with a mean age of 17.2 (SD 6.9) and a nearly equal sex distribution (52.3% were female). Internet-based social media sites were used by 80.8%, with Facebook being the most popular. Some 13.3% of the sample had posted comments about braces on these social media sites. Only 6.7% had considered obtaining information about orthodontic treatment from Internet-based social media sites, with the majority (81%) preferring to seek this information directly from their orthodontist. Nearly two-thirds of those who had difficulty remembering to wear their orthodontic appliances reported that a reminder application on their phone would be beneficial. A large proportion of orthodontic patients use Internet-based social media sites, although only a few currently use them to post about treatment-related topics. Social media sites may provide a useful channel of communication for patients seeking support. Further research is needed to evaluate the use of phone reminder applications in orthodontics.

  5. The INC. 500 and social media: Marketing research

    OpenAIRE

    Nora Ganim Barnes; Eric Mattson; Mira Marušić

    2008-01-01

    As a great challenge in communications, social media are widely accepted among the general population. Being very flexible and adaptable, they offer an opportunity of active participation to users, thus representing a public forum. This study presents the results of social media acceptance in the business world on a sample of the Inc. 500 companies in the US. The research found that familiarity, the value placed on social media and the use of different forms of social media are all related. T...

  6. Kronic hysteria: exploring the intersection between Australian synthetic cannabis legislation, the media, and drug-related harm.

    Science.gov (United States)

    Bright, Stephen J; Bishop, Brian; Kane, Robert; Marsh, Ali; Barratt, Monica J

    2013-05-01

    Having first appeared in Europe, synthetic cannabis emerged as a drug of concern in Australia during 2011. Kronic is the most well-known brand of synthetic cannabis in Australia and received significant media attention. Policy responses were reactive and piecemeal between state and federal governments. In this paper we explore the relationship between media reports, policy responses, and drug-related harm. Google search engine applications were used to produce time-trend graphs detailing the volume of media stories being published online about synthetic cannabis and Kronic, and also the amount of traffic searching for these terms. A discursive analysis was then conducted on those media reports that were identified by Google as 'key stories'. The timing of related media stories was also compared with self-reported awareness and month of first use, using previously unpublished data from a purposive sample of Australian synthetic cannabis users. Between April and June 2011, mentions of Kronic in the media increased. The number of media stories published online connected strongly with Google searches for the term Kronic. These stories were necessarily framed within dominant discourses that served to construct synthetic cannabis as pathogenic and created a 'moral panic'. Australian state and federal governments reacted to this moral panic by banning individual synthetic cannabinoid agonists. Manufacturers subsequently released new synthetic blends that they claimed contained new unscheduled chemicals. Policies implemented within in the context of 'moral panic', while well-intended, can result in increased awareness of the banned product and the use of new yet-to-be-scheduled drugs with unknown potential for harm. Consideration of regulatory models should be based on careful examination of the likely intended and unintended consequences. Such deliberation might be limited by the discursive landscape. Copyright © 2012 Elsevier B.V. All rights reserved.

  7. Image of Refugees and Asylum-Seekers in the Media: An Evaluation on Media Politics

    Directory of Open Access Journals (Sweden)

    Suat Kolukırık

    2009-06-01

    Full Text Available The case of refugees and asylum-seekers constitutes one of the most important problems of today’s developed and developing countries. Immigration and sanctuary which arise generally from economic causes have reached a more intensified state due to deficiencies in the process of democratization and establishment of an environment of peace. Although it is difficult to provide an exact number, it is observed that a population of more than 10 million people in the world today continue their lives outside their home countries and seek new environments for survival. It is known that refugee mobility follows a route from the south to northern countries and in the case of Turkey it is realized along the coastal lines and through east/south highways, and occupies a significant area of coverage in the Turkish printed media. This article aims to analyze and evaluate the media language and discourse on the lives of refugees or asylum seekers through the perspective of democratization and human rights. Critical discourse analysis will be used to analyze the main axes of enquiry which include the news released in the Turkish printed media on refugees and asylum seekers, the approach adopted in shaping such news coverage, the messages they convey, and their role in molding public opinion

  8. Task Characteristics, Managerial Socialization, and Media Selection.

    Science.gov (United States)

    Donabedian, Bairj; McKinnon, Sharon M.; Bruns, William J., Jr.

    1998-01-01

    Questions why managers choose one communication medium in preference to another. Proposes a role for social factors in media selection. Finds, employing a large field-collected sample, strong support for Information Richness Theory, a rational-choice model connecting managers' media choice to task characteristics like variety and analyzability.…

  9. Use and Acceptance of Social Media among Health Educators

    Science.gov (United States)

    Hanson, Carl; West, Joshua; Neiger, Brad; Thackeray, Rosemary; Barnes, Michael; McIntyre, Emily

    2011-01-01

    Background: As social media use grows in popularity, health educators are challenged to think differently about how to communicate with audiences. Purpose: The purpose of this study was to explore social media use and factors that determine acceptance of social media use among health educators. Methods: A random sample of Certified Health…

  10. Offsite doses from SRP radioactive releases - 1985

    International Nuclear Information System (INIS)

    Marter, W.L.

    1986-01-01

    This memorandum summarizes the offsite doses from releases of radioactive materials to the environment from SRP operations in 1985. These doses were calculated for inclusion in the environmental report for 1985 to be issued by the Health Protection Department (DPSPU-86-30-1). The environmental report is prepared annually for distribution to state environmental agencies, the news media, and interested members of the public. More detailed data on offsite exposures by radionuclide and exposure pathway will be included in the environmental report

  11. Reconstructing random media

    International Nuclear Information System (INIS)

    Yeong, C.L.; Torquato, S.

    1998-01-01

    We formulate a procedure to reconstruct the structure of general random heterogeneous media from limited morphological information by extending the methodology of Rintoul and Torquato [J. Colloid Interface Sci. 186, 467 (1997)] developed for dispersions. The procedure has the advantages that it is simple to implement and generally applicable to multidimensional, multiphase, and anisotropic structures. Furthermore, an extremely useful feature is that it can incorporate any type and number of correlation functions in order to provide as much morphological information as is necessary for accurate reconstruction. We consider a variety of one- and two-dimensional reconstructions, including periodic and random arrays of rods, various distribution of disks, Debye random media, and a Fontainebleau sandstone sample. We also use our algorithm to construct heterogeneous media from specified hypothetical correlation functions, including an exponentially damped, oscillating function as well as physically unrealizable ones. copyright 1998 The American Physical Society

  12. Social Media Programs at the National Optical Astronomy Observatory

    Science.gov (United States)

    Sparks, Robert T.; Walker, Constance Elaine; Pompea, Stephen M.

    2015-08-01

    Observatories and other science research organizations want to share their research and activities with the public. The last several years, social media has become and increasingly important venue for communicating information about observatory activities, research and education and public outreach.The National Optical Astronomy Observatory (NOAO) uses a wide variety of social media to communicate with different audiences. NOAO is active on social media platforms including Facebook, Twitter, Google+ and Pinterest. Our social media accounts include those for the National Optical Astronomy Observatory, Cerro Tololo Inter-American Observatory, Kitt Peak National Observatory and our dark skies conservation program Globe at Night.Our social media programs have a variety of audiences. NOAO uses social media to announce and promote NOAO sponsored meetings, observatory news and proposal deadlines to the professional astronomical community. Social media accounts are used to disseminate NOAO press releases, images from the observatory and other science using data from NOAO telescopes.Social media is important in our Education and Public Outreach programs (EPO). Globe at Night has very active facebook and twitter accounts encouraging people to become involved in preserving dark skies. Social media plays a role in recruiting teachers for professional development workshops such as Project Astro.NOAO produces monthly podcasts for the 365 Days of Astronomy podcast featuring interviews with NOAO astronomers. Each podcast highlights the science of an NOAO astronomer, an NOAO operated telescope or instrument, or an NOAO program. A separate series of podcasts is produced for NOAO’s Dark Skies Education programs. All the podcasts are archived at 365daysofastronomy.org.

  13. Air-Stimulated ATP Release from Keratinocytes Occurs through Connexin Hemichannels

    Science.gov (United States)

    Barr, Travis P.; Albrecht, Phillip J.; Hou, Quanzhi; Mongin, Alexander A.; Strichartz, Gary R.; Rice, Frank L.

    2013-01-01

    Cutaneous ATP release plays an important role in both epidermal stratification and chronic pain, but little is known about ATP release mechanisms in keratinocytes that comprise the epidermis. In this study, we analyzed ATP release from cultured human neonatal keratinocytes briefly exposed to air, a process previously demonstrated to trigger ATP release from these cells. We show that exposing keratinocytes to air by removing media for 15 seconds causes a robust, long-lasting ATP release. This air-stimulated ATP release was increased in calcium differentiated cultures which showed a corresponding increase in connexin 43 mRNA, a major component of keratinocyte hemichannels. The known connexin hemichannel inhibitors 1-octanol and carbenoxolone both significantly reduced air-stimulated ATP release, as did two drugs traditionally used as ABC transporter inhibitors (glibenclamide and verapamil). These same 4 inhibitors also prevented an increase in the uptake of a connexin permeable dye induced by air exposure, confirming that connexin hemichannels are open during air-stimulated ATP release. In contrast, activity of the MDR1 ABC transporter was reduced by air exposure and the drugs that inhibited air-stimulated ATP release had differential effects on this transporter. These results indicate that air exposure elicits non-vesicular release of ATP from keratinocytes through connexin hemichannels and that drugs used to target connexin hemichannels and ABC transporters may cross-inhibit. Connexins represent a novel, peripheral target for the treatment of chronic pain and dermatological disease. PMID:23457608

  14. Antimicrobial beeswax coated polylactide films with silver control release capacity.

    Science.gov (United States)

    Martínez-Abad, Antonio; Lagarón, Jose Maria; Ocio, María Jose

    2014-03-17

    Although the application of silver based antimicrobial systems is a widespread technology, its implementation in areas such as food packaging is still challenging. The present paper describes the fabrication of poly(lactic acid) (PLA) coated with beeswax with controlled release properties for sustained antimicrobial performance. Release of silver ions from the polymers was monitored voltammetrically under various conditions (surface contact, immersion in various liquid media and at different pH values) throughout at least 7days. A higher release was noted with decreasing pH while surface release was much slower than the release when immersed in liquid medium. While uncoated films demonstrated a high burst release which in some instances implied surpassing some current migration restrictions (food), the addition of a beeswax layer allowed a sustained release of the antimicrobial compound. Increasing the thickness of the beeswax layer resulted in an increase in the water barrier properties of the films while reducing the relatively constant values of sustained release. Antimicrobial performance was correlated with the release of silver ions, indicating threshold concentrations for biocide action of films displayed a strong bactericidal effect against Salmonella enterica. The application of this functional barrier thus offers the possibility of tuning the release profiles of the films to suit a specific application and puts forth the possible suitability of these materials for food packaging or other migration sensitive applications. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. Acceptability of oral iodinated contrast media: a head-to-head comparison of four media

    Science.gov (United States)

    Ngan-Soo, E; McCoubrie, P

    2013-01-01

    Objective: To assess the palatability of iodinated oral contrast media commonly used in abdominopelvic CT and CT colonography (CTC). Methods: 80 volunteers assessed the palatability of a 20-ml sample of a standard 30 mg ml−1 dilution of Omnipaque® (iohexol; GE Healthcare, Cork, Ireland), Telebrix® (meglumine ioxithalamate; Guerbet, Aulnay-sous-Bois, France), Gastromiro® (iopamidol; Bracco, High Wycombe, UK) and Gastrografin® (sodium diatrizoate and meglumine diatrizoate; Bayer, Newbury, UK) in a computer-generated random order. Results: Gastrografin is rated significantly less palatable than the remaining media (pcontrast media than both Gastromiro and Gastrografin, which has potential implications in compliance with both abdominopelvic CT and CTC. PMID:23564884

  16. Susceptibility for thin ideal media and eating styles

    NARCIS (Netherlands)

    Anschutz, Doeschka J; Engels, Rutger C M E; van Strien, Tatjana

    This study examined the relations between susceptibility for thin ideal media and restrained, emotional and external eating, directly and indirectly through body dissatisfaction. Thin ideal media susceptibility, body dissatisfaction and eating styles were measured in a sample of 163 female students.

  17. Nursing Students' Use of Electronic and Social Media: Law, Ethics, and E-Professionalism.

    Science.gov (United States)

    Westrick, Susan J

    2016-01-01

    This article discusses the promotion of professionalism in nursing students with regard to the use of electronic and social media. Misuse of social media can lead to disciplinary actions and program dismissal for students and to legal actions and lawsuits for nursing programs. Programs are concemed about breaches of patient confidentiality and release of private or inappropriate information that jeopardizes clinical placements and relationships. The American Nurses Association Code of Ethics and National Council of State Boards of Nursing social media guidelines provide a foundation for promoting e-professionalism in students. Recent law cases involving students who were dismissed from nursing programs due to social media misuse are analyzed. Schools need policies that clearly establish expectations and the consequences of misuse of social media platforms. Lessons learned from the legal cases presented provide further guidance for both nursing students and nursing programs.

  18. A curcumin activated carboxymethyl cellulose-montmorillonite clay nanocomposite having enhanced curcumin release in aqueous media.

    Science.gov (United States)

    Madusanka, Nadeesh; de Silva, K M Nalin; Amaratunga, Gehan

    2015-12-10

    A novel curcumin activated carboxymethylcellulose-montmorillonite nanocomposite is reported. A superabsorbent biopolymer; carboxymethyl cellulose (CMC) was used as an emulsifier for curcumin which is a turmeric derived water insoluble polyphenolic compound with antibacterial/anti-cancer properties. Montmorillonite (MMT) nanoclay was incorporated in the formulation as a matrix material which also plays a role in release kinetics. It was observed that water solubility of curcumin in the nanocomposite has significantly increased (60% release within 2h and 30 min in distilled water at pH 5.4) compared to pure curcumin. The prepared curcumin activated carboxymethylcellulose-montmorillonite nanocomposite is suitable as a curcumin carrier having enhanced release and structural properties. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Media Komunitas dan Media Literacy

    Directory of Open Access Journals (Sweden)

    Pawito .

    2013-12-01

    Full Text Available Abstract:This essay deals with community media in relation to media literacy. After a short discussion on a number of community media characters is made the essay goes further with somewhat detail theoretical presumptions of the roles of media community with respect primarily to the development as Amartya Sen mentioned about. The author suggests that community media may play some significant roles in the development including (a disseminating information (from varieties of perspective, (b facilitating public discussion, (c helping to reach solutions of problems, (d encouraging participations, and (e encouraging the development of media literacy. Regarding the last point the author remarks that media community may have a dual-roles i.e facilitating community’s member in media participation and facilitating community’s member in media education.

  20. [Blood donation in the media between 1950 and 1980].

    Science.gov (United States)

    Lefrère, J-J; Garraud, O

    2016-02-01

    Anecdotes, such as found in the media and chiefly the humor journals and magazines aim at bringing revisited insights on society subjects, which can even be the most serious. Anecdotes reported here on blood transfusion and the transfusion environment, that were retrieved from French news released in the media press between the 1950s to 1980s give a view on what has been achieved since then, but also on what is at a standstill by some incapability in moving forward or in changing minds. Those anecdotes would be used to stimulate or refresh debates in transfusion related-ethics. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  1. Alitalia's Crisis in the Media

    DEFF Research Database (Denmark)

    Romenti, Stefania; Valentini, Chiara

    2010-01-01

    Purpose – The purpose of this investigation is to explore Alitalia and the Italian Government’s crisis response strategies (CRSs) implemented in three specific periods of 2008 to understand Alitalia and the Italian Government’s approach in communicating with media stakeholders as well as to examine...... in a larger measure excuse strategies, especially in the later period. In terms of news coverage, the content analysis shows that the CRSs reported by the international press correspond to those in the press releases whereas the Italian newspapers preferred other frames than those offered by Alitalia...

  2. HTML5 Media

    CERN Document Server

    Powers, Shelley

    2011-01-01

    If you're a web developer or designer familiar with CSS and JavaScript, this tightly focused introduction shows you how to add HTML5 media elements to your web pages, and how to provide custom controls for letting web visitors interact with the content. You'll also learn how to provide subtitles and captions, using file formats that work in browsers now. This book includes code samples and downloadable examples to help you take full advantage of audio and video in your web pages. Ensure your audio or video works in all browsers that support HTML5 media elementsLearn about widely supported me

  3. Journalism Practice and Social Media

    Directory of Open Access Journals (Sweden)

    Hanifi KURT

    2014-12-01

    Full Text Available Social media applications which have been emerging with the spread of developing internet technology, have deeply transformed all variants of the phenomenon of the communication, including mass communication. Social media has transformed phenomenon of communication into an accelerant and interactive format that can be contributed continuously; while, mass media carries the information which is designed from a certain center (newsrooms to masses conventionally. It can be expressed that social media applications, corresponding to the different forms of interactive communication, such as internet forums, weblogs, social blogs, wikis, photo/video/text sharing applications/websites, have also created significant changes in the field of journalism. This new (social media which provides readers to participate in the news texts actively, even provides the opportunity to every ordinary person (who has an internet connection for being a citizen journalist, is not only a new source of news for journalists, but it is also seen as a new reporting enviroment that provides possibility for making profession of journalism in an interactive format. This study aims to examine the social media usage habits of journalists and their relation with social media. The journalists who work for local and national media organizations located in İzmir, are determined as a sample of this study and the questionnaire/survey method is chosen for to achieve specific data for the aim of the study

  4. Suitability of Commercial Transport Media for Biological Pathogens under Nonideal Conditions

    Directory of Open Access Journals (Sweden)

    Kyle Hubbard

    2011-01-01

    Full Text Available There is extensive data to support the use of commercial transport media as a stabilizer for known clinical samples; however, there is little information to support their use outside of controlled conditions specified by the manufacturer. Furthermore, there is no data to determine the suitability of said media for biological pathogens, specifically those of interest to the US military. This study evaluates commercial off-the-shelf (COTS transport media based on sample recovery, viability, and quality of nucleic acids and peptides for nonpathogenic strains of Bacillus anthracis, Yersinia pestis, and Venezuelan equine encephalitis virus, in addition to ricin toxin. Samples were stored in COTS, PBST, or no media at various temperatures over an extended test period. The results demonstrate that COTS media, although sufficient for the preservation of nucleic acid and proteinaceous material, are not capable of maintaining an accurate representation of biothreat agents at the time of collection.

  5. Measuring the level of public understanding of total solar eclipse from the mass media: Palembang as sample

    Science.gov (United States)

    Purwati, F. G.; Ekawanti, N.; Luthfiandari; Premadi, P. W.

    2016-11-01

    The Total Solar Eclipse (TSE) on the 9th March 2016 received a huge attention from the mass media. Some of them intensively write articles about it even months before the TSE day. As we know media plays strategic role not only in raising public awareness but also interest. The aim of this project is to study the relation between the number of accesses to the media information and how well public learned the information delivered by the media. We prepared questionnaire consisting of seven semi-multiple choices on how public got information about TSE. We gave them choices of what they had heard to measure their basic understanding of TSE. Furthermore we add two “wrong” choices in the last questions to identify less serious respondents. We analyze 60 respondents of Palembang who visited Ampera bridge area. Our result shows no correlation between the number of information access and the level of understanding about TSE. We also found that local media did not provide the scientific content of TSE as well as the national media.

  6. Adsorption and release of micronutrients by humin extracted from peat samples

    Energy Technology Data Exchange (ETDEWEB)

    Goveia, Danielle; Melo, Camila de A.; Oliveira, Lilian K. de; Rocha, Julio Cesar [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Araraquara, SP (Brazil). Instituto de Quimica; Fraceto, Leonardo F.; Rosa, Andre Henrique, E-mail: ahrosa@sorocaba.unesp.br [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Sorocaba, SP (Brazil). Departamento de Engenharia Ambiental; Dias Filho, Newton Luiz [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Ilha Solteira, SP (Brazil). Departamento de Fisica e Quimica

    2013-05-15

    The objective of this work was to investigate the adsorption of micronutrients in humin and to verify the ability to release these elements in water. The first step was to determine the adsorption capacity of humin for several essential plant micronutrients and check the kinetic parameters. The order of adsorption was Zn < Ni < Co < Mn < Mo < Cu < Fe, whereas Zn showed maximum values of ca. 2.5 mg g-1 and Fe values of ca. 0.5 mg g-1 for systems containing 1 g of humin. Iron presented higher percentages of release (ca. 100%) and Co the lowest percentages (0.14%). The findings suggested that the use of humin enriched with micronutrients can be a promising alternative for the fertilization of agricultural soils, with the additional benefit of incorporating organic matter present in the form of humic substances into the soil and improving the agricultural productivity. (author)

  7. The JMC Innovation Project: A Pivotal Moment for Journalism, Media and Communication Education: Assessing the State of Innovation

    Science.gov (United States)

    Richards, Allan; Fitzpatrick, Kathy R.

    2018-01-01

    The JMC Innovation Project recently released its first report, "The 'New' JMC: Creating Cultures of Innovation in Schools of Journalism, Media and Communication," which assessed the scope and status of innovation in schools and colleges of journalism, media and communication (JMC), based on personal interviews with 70 deans and directors…

  8. Fluid dynamics in porous media with Sailfish

    Science.gov (United States)

    Coelho, Rodrigo C. V.; Neumann, Rodrigo F.

    2016-09-01

    In this work we show the application of Sailfish to the study of fluid dynamics in porous media. Sailfish is an open-source software based on the lattice-Boltzmann method. This application of computational fluid dynamics is of particular interest to the oil and gas industry and the subject could be a starting point for an undergraduate or graduate student in physics or engineering. We built artificial samples of porous media with different porosities and used Sailfish to simulate the fluid flow through them in order to calculate their permeability and tortuosity. We also present a simple way to obtain the specific superficial area of porous media using Python libraries. To contextualise these concepts, we analyse the applicability of the Kozeny-Carman equation, which is a well-known permeability-porosity relation, to our artificial samples.

  9. Experimental and Modeling Study on Detachment of Silver Nanoparticles in Saturated Granular Media

    Science.gov (United States)

    Kim, I.; Jeon, C. H.; Lawler, D. F.

    2017-12-01

    The detachment of citrate-capped silver nanoparticles (AgNPs) previously captured in a column packed with 350-μm glass beads was investigated either by increasing the hydrodynamic force (filtration velocity) or by reducing electrosteric attraction. Overall, the physical enforcement showed negligible (0.4 0.7%) release of attached AgNPs while the chemically-driven force resulted in the noticeable release up to 25.5% of attached AgNPs. Among the chemical parameters tested in this study, Na ionic strength reduction clearly demonstrated the reversible deposition in the secondary energy minimum of classical DLVO theory, yielding the most significant release of the attached AgNPs. The immediate and transient AgNP release after the ionic strength reduction further corroborated the weak deposition. However, an insignificant release was observed with Ca ionic strength reduction due to the strong Ca-citrate complexation and the subsequent deposition in the primary energy minimum; calculations indicated that the depth of the secondary energy minimum was only 1/10 that of the Na ion case. The natural organic matter (NOM) coating on both AgNPs and granular media resulted in approximately 6.1% greater AgNP release compared to the case without NOM coating, indicating additional weak deposition due to the reduced steric attraction between AgNPs and granular media. A modified filtration model in agreement with the experimental data provided the estimated detachment coefficient as a transient AgNP releasing capacity independent of the amount of attached AgNPs. The marginal difference between the detachment coefficients from Na ionic strength reduction and NOM coating indicates the release potential by NOM coating was possibly underestimated in the experimental study due to a lesser amount of the initially attached AgNPs. The findings provide insights into chemical factors on possible reentrainment behavior of the engineered nanoparticles in soil and groundwater contamination.

  10. Media Kompos Serbuk Gergaji Kayu Sengon dan Pupuk Lepas Lambat untuk Meningkatkan Pertumbuhan Semai Pinus merkusii di KPH Banyumas Timur

    Directory of Open Access Journals (Sweden)

    Suryo Hardiwinoto

    2013-01-01

    Full Text Available Effects of Composted Sawdust of Falcata Media and Slow Release Fertilizer to Promote  Pinus merkusii Seedling growth in Banyumas Timur FMU Physical and chemical properties of the potting media, especially porosity and nutrient availability, are required to produce good quality seedlings of pine (Pinus merkusii Jungh et de Vries. Composted sawdust of sengon (Paraserianthes falcataria wood is a potential material to be used for growing media of pine seedlings. However, since this material contains low nutrients, addition of a slow release fertilizer is required to meet the nutrient demand of seedling growth. The objective of this research was to determine the effects of wood sawdust compost and slow release fertilizer on the growth of pine seedlings. The experiment was arranged in a completely randomized design with two factors and four replications. The first factor was the rate of sawdust compost and the second factor was the rate of slow release fertilizer. Height and root-collar diameter were measured at 6 months of age. As the results, sawdust compost and slow release fertilizer gave a significant effect on height and diameter growths. However, the effect of sawdust compost on seedling growth depended on the rate of fertilizer. Combination treatment that gave the best seedlings growth was 100% sawdust compost + 0% soil (and 12 g fertilizer /1.5 liter media. The seedlings applied with this treatment had the mean height of 8.72 cm and diameter of 2.24 mm, which were significantly greater than the control with the mean height and mean diameter of 1.87 cm and 1.15 mm respectively.

  11. Interleukin-1beta-induced release of matrix proteins into culture media causes inhibition of mineralization of nodules formed by periodontal ligament cells in vitro.

    Science.gov (United States)

    Chien, H H; Lin, W L; Cho, M I

    1999-05-01

    media after [35S]-methionine labeling showed their deposition primarily in the mineralized nodules of the Dex group, and their release into the media in the IL-1 group. Immunogold labeling demonstrated the location of OPN and BSP in mineralized nodules of the Dex group, but no significant labeling occurred in the nodule-like structures from the IL-1 group. Interestingly, IL-1 treatment increased the expression of collagenase mRNA by sevenfold, compared with that of the Dex group. These data suggest that the IL-1-induced formation of unmineralized nodules by PDL cells results not so much from the downregulated formation of matrix proteins, which plays a crucial role in the mineralization process, as from their release into the culture media. Finally, collagenase synthesis upregulated by IL-1 may be involved in this process.

  12. Assessing the Use of Media Reporting Recommendations by the World Health Organization in Suicide News Published in the Most Influential Media Sources in China, 2003-2015.

    Science.gov (United States)

    Chu, Xin; Zhang, Xingyi; Cheng, Peixia; Schwebel, David C; Hu, Guoqing

    2018-03-05

    Public media reports about suicide are likely to influence the population's suicidal attempts and completed suicides. Irresponsible reports might trigger copycat suicidal behaviors, while responsible reports may help reduce suicide rates. The World Health Organization (WHO) released recommendations to encourage responsible suicide reports in 2008. However, little is known about whether these recommendations are reflected in the suicide news for most countries, including China. In this study, we assessed the responsibility of suicide stories published in the most influential newspaper and Internet media sources in China from 2003 to 2015, using the media reporting recommendations by the World Health Organization (WHO). In total, 3965 and 1836 eligible stories from newspaper and Internet-based media, respectively, were included in the study. Newspapers and Internet-based media performed similarly in applying WHO recommendations to report suicide news. Three recommendations were applied in over 88% of suicide stories. However, four recommendations were seldom applied, including offering information about where to seek help and linking the suicide event to mental disorders. Government and the journalism industry should work together to improve media reporting of news about suicide in China.

  13. Hydrogen retention and release from uranium dioxide

    International Nuclear Information System (INIS)

    Sherman, D.F.

    1987-08-01

    The ceramic samples (UO 2 ) are exposed to high pressure hydrogen gas at a fixed temperature for a time sufficient to achieve equilibrium. After rapid quenching, the hydrogen-saturated sample is transferred to a vacuum-outgassing furnace. The sample is outgassed in a linear temperature ramp and the released hydrogen is detected by an in-situ mass spectrometer. This technique measures the rate of release of hydrogen with a sensitivity level of about 2 ng of hydrogen (as D 2 ) per hour. In this study, experiments were conducted on both polycrystalline and single-crystal UO 2 . Experimental variables included temperature (1000 to 1600 0 C) and infusion pressure (5 to 32 atm D 2 ), and for the polycrystalline specimen, stoichiometry. Dissolution of H 2 in both single-crystal and polycrystalline UO 2 was found to obey Seivert's law. The Sievert's law constant of deuterium in single-crystal UO 2 was determined to be: 3.0 x 10 7 exp(-235 kJ/RT) ppM atomic/√atm and for polycrystalline UO 2 : 5.5 x 10 4 exp(-100 kJ/RT) ppM atomic/√atm. The solubility of hydrogen in hypostoichiometric urania was found to be up to three orders of magnitude greater than in stoichiometric UO 2 depending on the O/U ratios, implying the anion vacancy is the primary solution site in the UO 2 lattice. The release-rate curves for the single crystal and polycrystalline UO 2 specimens exhibited multiple peaks, with most of the deuterium released between 600 and 1200 0 C for the polycrystalline samples, and between 700 and 1800 0 C in the single-crystal specimens. This release of hydrogen from UO 2 could not be adequately modeled as diffusion or diffusion with trapping and resolution. It was determined that release was governed by release from traps in both the polycrystalline and single crystal UO 2 specimens. 40 refs., 72 figs., 6 tabs

  14. Effects of Iron on DNA Release and Biofilm Development by Pseudomonas Aeruginosa

    DEFF Research Database (Denmark)

    Yang, Liang; Barken, Kim Bundvig; Skindersø, Mette Elena

    2007-01-01

    Extracellular DNA is one of the major matrix components in Pseudomonas aeruginosa biofilms. It functions as an intercellular connector and plays a role in stabilization of the biofilms. Evidence that DNA release in P. aeruginosa PAO1 biofilms is controlled by the las-rhl and pqs quorum-sensing sy......Extracellular DNA is one of the major matrix components in Pseudomonas aeruginosa biofilms. It functions as an intercellular connector and plays a role in stabilization of the biofilms. Evidence that DNA release in P. aeruginosa PAO1 biofilms is controlled by the las-rhl and pqs quorum......-sensing systems has been previously presented. This paper provides evidence that DNA release in P. aeruginosa PAO1 biofilms is also under iron regulation. Experiments involving cultivation of P. aeruginosa in microtitre trays suggested that pqs expression, DNA release and biofilm formation were favoured in media...

  15. From Augmentation Media to Meme Media.

    Science.gov (United States)

    Tanaka, Yuzuru

    Computers as meta media are now evolving from augmentation media vehicles to meme media vehicles. While an augmentation media system provides a seamlessly integrated environment of various tools and documents, meme media system provides further functions to edit and distribute tools and documents. Documents and tools on meme media can easily…

  16. Does media reputation affect properties of accounts payable?

    NARCIS (Netherlands)

    Van den Bogaerd, M.; Aerts, Walter

    We examine economic benefits of a firm's corporate reputation by investigating the association between its media reputation and properties of trade payables in a sample of listed UK firms. Our results document a significant positive association between a firm's overall media reputation and both the

  17. Application of tumbling melt granulation (TMG) method to prepare controlled-release fine granules.

    Science.gov (United States)

    Maejima, T; Kubo, M; Osawa, T; Nakajima, K; Kobayashi, M

    1998-03-01

    The tumbling melt granulation (TMG) method was applied to prepare controlled-release fine granules of diltiazem hydrochloride (DH). The entire process, from the preparation of the cores by the adherence of DH to the sucrose crystal to the subsequent coating of the controlled-release layer, was performed without using any solvent. A mixture of meltable material, talc, and ethylcellulose was used for the controlled-release layer and controlled-release fine granules approximately 400 microns in diameter were obtained with excellent producibility. The dissolution rate of DH from these fine granules was similar to that of a once-a-day dosage form obtained in the market; further, the dependency of the dissolution profile on pH of the media was less. Thus, it was concluded that this TMG method was very useful for preparing not only controlled-release beads of granule size (usually 500 to 1400 microns) but also fine granules.

  18. Social media management and media environment

    Directory of Open Access Journals (Sweden)

    Šiđanin Iva

    2012-01-01

    Full Text Available The paper deals with the system of services that social media management can offer to a variety of users. As social media systems are emerging, social media management can strengthen teams in social media and help to manage numerous social channels and distribution of social information from one place. Social media management is a system of procedures that are used to manage the flow of information in the environment of social media. This involves connecting with social media like Facebook, Twitter, LinkedIn, Plaxo, Ecademy, YouTube and many others, then the aggregation and management of social data. Social media management services are analysed through various fields, such as managing multiple social media profiles, mail scheduling and filtering, reporting and analytics. Social media management enables managing personal business through social media, which contributes to a significant reduction in expenditures. The paper also discusses the importance of social media management in marketing activities and various forms of social promotion, which allow companies to easily reach their customers.

  19. Investigating the barriers on media privatization

    Directory of Open Access Journals (Sweden)

    Roghiyeh Jame

    2013-01-01

    Full Text Available During the past few years, there has been growing interests in reducing cost of products and services among developing countries. Privatization is believed to be one of the most important techniques to increase relative efficiencies of publically held organizations. In this paper, we study important barriers on privatization of television (TV media industry in Iran. The proposed study of this paper designs and distributes a questionnaire using a sample of 234 out of 600 graduate students who were enrolled in media communication studies and examined six hypotheses based on one-side t-student. The survey considers different factors influencing privatization of TV media industry. The results of the investigation indicate that the cost of TV production, short and long-term investment security, people's interest on investing on TV media industry, building appropriate culture, cultural obstacles and economic barriers influence media privatization, significantly.

  20. Fluid dynamics in porous media with Sailfish

    International Nuclear Information System (INIS)

    Coelho, Rodrigo C V; Neumann, Rodrigo F

    2016-01-01

    In this work we show the application of Sailfish to the study of fluid dynamics in porous media. Sailfish is an open-source software based on the lattice-Boltzmann method. This application of computational fluid dynamics is of particular interest to the oil and gas industry and the subject could be a starting point for an undergraduate or graduate student in physics or engineering. We built artificial samples of porous media with different porosities and used Sailfish to simulate the fluid flow through them in order to calculate their permeability and tortuosity. We also present a simple way to obtain the specific superficial area of porous media using Python libraries. To contextualise these concepts, we analyse the applicability of the Kozeny–Carman equation, which is a well-known permeability–porosity relation, to our artificial samples. (paper)

  1. Assessing the Use of Media Reporting Recommendations by the World Health Organization in Suicide News Published in the Most Influential Media Sources in China, 2003–2015

    Directory of Open Access Journals (Sweden)

    Xin Chu

    2018-03-01

    Full Text Available Public media reports about suicide are likely to influence the population’s suicidal attempts and completed suicides. Irresponsible reports might trigger copycat suicidal behaviors, while responsible reports may help reduce suicide rates. The World Health Organization (WHO released recommendations to encourage responsible suicide reports in 2008. However, little is known about whether these recommendations are reflected in the suicide news for most countries, including China. In this study, we assessed the responsibility of suicide stories published in the most influential newspaper and Internet media sources in China from 2003 to 2015, using the media reporting recommendations by the World Health Organization (WHO. In total, 3965 and 1836 eligible stories from newspaper and Internet-based media, respectively, were included in the study. Newspapers and Internet-based media performed similarly in applying WHO recommendations to report suicide news. Three recommendations were applied in over 88% of suicide stories. However, four recommendations were seldom applied, including offering information about where to seek help and linking the suicide event to mental disorders. Government and the journalism industry should work together to improve media reporting of news about suicide in China.

  2. Safety in online media – freedom of the media; safety of media actors and media education

    OpenAIRE

    Moeller, Ch

    2013-01-01

    In this paper, prepared for the international conference ‘Mass Media – Society – Education: Media Safety Problems’ at the Chelyabinsk State University’s Department for Journalism and Media Education from September 30 – October 3, 2013, I would like to address three dimensions of media safety and security in online media.

  3. Releasable activity and maximum permissible leakage rate within a transport cask of Tehran Research Reactor fuel samples

    Directory of Open Access Journals (Sweden)

    Rezaeian Mahdi

    2015-01-01

    Full Text Available Containment of a transport cask during both normal and accident conditions is important to the health and safety of the public and of the operators. Based on IAEA regulations, releasable activity and maximum permissible volumetric leakage rate within the cask containing fuel samples of Tehran Research Reactor enclosed in an irradiated capsule are calculated. The contributions to the total activity from the four sources of gas, volatile, fines, and corrosion products are treated separately. These calculations are necessary to identify an appropriate leak test that must be performed on the cask and the results can be utilized as the source term for dose evaluation in the safety assessment of the cask.

  4. Metal contamination in environmental media in residential areas around Romanian mining sites

    Science.gov (United States)

    Hard-rock mining for metals, such as gold, silver, copper, zinc, iron and others, is recognized to have a significant impact on the environmental media, soil and water, in particular. Toxic contaminants released from mine waste to surface water and groundwater is the primary co...

  5. Effect of bioceramic functional groups on drug binding and release kinetics

    Science.gov (United States)

    Trujillo, Christopher

    Bioceramics have been studied extensively as drug delivery systems (DDS). Those studies have aimed to tailor the drug binding and release kinetics to successfully treat infections and other diseases. This research suggests that the drug binding and release kinetics are predominantly driven by the functional groups available on the surface of a bioceramic. The goal of the present study is to explain the role of silicate and phosphate functional groups in drug binding to and release kinetics from bioceramics. alpha-cristobalite (Cris; SiO2) particles (90-150 microm) were prepared and doped with 0 microg (P-0), 39.1 microg (P-39.1), 78.2 microg (P-78.2), 165.5 microg (P-165.5) or 331 microg (P-331) of P 2O5 per gram Cris, using 85% orthophosphoric (H3PO 4) acid and thermal treatment. The material structure was analyzed using X-ray diffraction (XRD) with Rietveld Refinement and Fourier Transform Infrared (FTIR) spectroscopy with Gaussian fitting. XRD demonstrated an increase from sample P-0 (170.5373 A3) to P-331 (170.6466 A 3) in the unit cell volume as the P2O5 concentration increased in the material confirming phosphate silicate substitution in Cris. Moreover, FTIR showed the characteristic bands of phosphate functional groups of nu4 PO4/O-P-O bending, P-O-P stretching, P-O-P bending, P=O stretching, and P-O-H bending in doped Cris indicating phosphate incorporation in the silicate structure. Furthermore, FTIR showed that the nu4 PO4/O-P-O bending band around 557.6 cm-1 and P=O stretching band around 1343.9 cm-1 increased in area for samples P-39.1 to P-331 from 3.5 to 10.5 and from 10.1 to 22.4, respectively due to phosphate doping. In conjunction with the increase of the nu4 PO4/O-P-O bending band and P=O stretching band, a decrease in area of the O-Si-O bending bands around 488.1 and 629.8 cm-1 was noticed for samples P-39.1 to P-331 from 5 to 2 and from 11.8 to 5.4, respectively. Furthermore, Cris samples (200 mg, n=5 for each sample) were immersed separately in

  6. Biodegradation of ion-exchange media

    International Nuclear Information System (INIS)

    Bowerman, B.S.; Clinton, J.H.; Cowdery, S.R.

    1988-08-01

    Ion-exchange media, both bead resins and powdered filter media, are used in nuclear power plants to remove radioactivity from process water prior to reuse or environmental discharge. Since the ion- exchange media are made from synthetic hydrocarbon-based polymers, they may be susceptible to damage from biological activity. The purpose of this study was to investigate some of the more basic aspects of biodegradation of ion-exchange media, specifically to evaluate the ability of microorganisms to utilize the ion-exchange media or materials sorbed on them as a food source. The ASTM-G22 test, alone and combined with the Bartha Pramer respirometric method, failed to indicate the biodegradability of the ion-exchange media. The limitation of these methods was that they used a single test organism. In later phases of this study, a mixed microbial culture was grown from resin waste samples obtained from the BNL High Flux Beam Reactor. These microorganisms were used to evaluate the susceptibility of different types of ion-exchange media to biological attack. Qualitative assessments of biodegradability were based on visual observations of culture growths. Greater susceptibility was associated with increased turbidity in solution indicative of bacterial growth, and more luxuriant fungal mycelial growth in solution or directly on the ion-exchange resin beads. 21 refs., 9 figs., 18 tabs

  7. Study of BSA protein adsorption/release on hydroxyapatite nanoparticles

    Science.gov (United States)

    Swain, Sanjaya Kumar; Sarkar, Debasish

    2013-12-01

    Three different spherical, rod and fibrous morphologies of hydroxyapatite (HA) nanoparticles have been prepared through control over the processing parameters like temperature, pH and Ca:P ratio. Protein adsorption/release with respect to HA nanoparticle morphologies are investigated using model protein bovine serum albumin (BSA). BSA adsorption on HA nanoparticles follows Langmuir adsorption isotherm. Thermal analysis and FT-IR spectrum confirms the BSA adhesion and retention of their secondary structure. High surface area with high Ca:P ratio nanorod adsorbs relatively more amount (28 mg BSA/gm of nanorod HA) of BSA within 48 h in comparison with counterpart fibroid and spherical morphologies. Slow and steady BSA release (75 wt% of adsorbed BSA in 96 h) from nanorod HA is found as futuristic drug delivery media.

  8. Nitrogen Released From Organic Residues Using 15N

    International Nuclear Information System (INIS)

    Galal, Y.G.M.; Gadalla, A.M.; Abdel Aziz, H.A.; Abdel Salam, A.A.; El-Degwy, S.M.A.

    2008-01-01

    Incubation technique was followed under laboratory condition to evaluate and determine the rate of organic residues decomposition as well as N released in media. Rice straw, soybean straw, and leuceana cutting residue were used. These materials were incubated on virgin sandy soil up to 90 days intervals. Cups with mixture of sand and organic residues were inoculated with fungi, bacteria and mixture of them. Un inoculated treatment was also included. Results showed that N released from the different organic materials was significant at 30 days of incubation. It seems that presence of Azotobacter was associated with enhanced demand on soluble N at this stage. Superiority of leucaena over the other two sources of rice straw and soybean straw occurred particularly during the 15 to 30.day period. In greenhouse experiment, the results indicated that N derived from organic materials was high and easily released from compost as mediated materials comparing to leucaena as undigested raw materials. In the same time, barley had more benefits from organic residues than lupine crop

  9. Alaska Geochemical Database (AGDB)-Geochemical data for rock, sediment, soil, mineral, and concentrate sample media

    Science.gov (United States)

    Granitto, Matthew; Bailey, Elizabeth A.; Schmidt, Jeanine M.; Shew, Nora B.; Gamble, Bruce M.; Labay, Keith A.

    2011-01-01

    The Alaska Geochemical Database (AGDB) was created and designed to compile and integrate geochemical data from Alaska in order to facilitate geologic mapping, petrologic studies, mineral resource assessments, definition of geochemical baseline values and statistics, environmental impact assessments, and studies in medical geology. This Microsoft Access database serves as a data archive in support of present and future Alaskan geologic and geochemical projects, and contains data tables describing historical and new quantitative and qualitative geochemical analyses. The analytical results were determined by 85 laboratory and field analytical methods on 264,095 rock, sediment, soil, mineral and heavy-mineral concentrate samples. Most samples were collected by U.S. Geological Survey (USGS) personnel and analyzed in USGS laboratories or, under contracts, in commercial analytical laboratories. These data represent analyses of samples collected as part of various USGS programs and projects from 1962 to 2009. In addition, mineralogical data from 18,138 nonmagnetic heavy mineral concentrate samples are included in this database. The AGDB includes historical geochemical data originally archived in the USGS Rock Analysis Storage System (RASS) database, used from the mid-1960s through the late 1980s and the USGS PLUTO database used from the mid-1970s through the mid-1990s. All of these data are currently maintained in the Oracle-based National Geochemical Database (NGDB). Retrievals from the NGDB were used to generate most of the AGDB data set. These data were checked for accuracy regarding sample location, sample media type, and analytical methods used. This arduous process of reviewing, verifying and, where necessary, editing all USGS geochemical data resulted in a significantly improved Alaska geochemical dataset. USGS data that were not previously in the NGDB because the data predate the earliest USGS geochemical databases, or were once excluded for programmatic reasons

  10. Impact of salt form and molecular weight of chitosan on swelling and drug release from chitosan matrix tablets.

    Science.gov (United States)

    Huanbutta, Kampanart; Cheewatanakornkool, Kamonrak; Terada, Katsuhide; Nunthanid, Jurairat; Sriamornsak, Pornsak

    2013-08-14

    Magnetic resonance imaging (MRI) and gravimetric techniques were used to assess swelling and erosion behaviors of hydrophilic matrix tablets made of chitosan. The impact of salt form, molecular weight (MW) and dissolution medium on swelling behavior and drug (theophylline) release was studied. The matrix tablets made of chitosan glycolate (CGY) showed the greatest swelling in both acid and neutral media, compared to chitosan aspartate, chitosan glutamate and chitosan lactate. MRI illustrated that swelling region of CGY in both media was not different in the first 100 min but glassy region (dry core) in 0.1N HCl was less than in pH 6.8 buffer. The tablets prepared from chitosan with high MW swelled greater than those of low MW. Moreover, CGY can delay drug release in the acid condition due to thick swollen gel and low erosion rate. Therefore, CGY may be suitably applied as sustained drug release polymer or enteric coating material. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Taking inventory on VOC releases from Amoco's Yorktown refinery

    International Nuclear Information System (INIS)

    Klee, H.H. Jr.; Schmitt, R.E.; Harrass, M.C.; Podar, M.K.

    1996-01-01

    Amoco's Yorktown, Virginia, refinery is a 35-year-old, 53,000 bbl/day facility that manufacturers gasoline, heating oil, liquid petroleum gas, sulfur, and coke. In a cooperative and voluntary effort, Amoco Corporation and the US Environmental Protection Agency conducted a joint project to study pollution prevention opportunities at an operating industrial facility. Source reduction efforts--key to pollution prevention strategies--require knowledge of specific sources of releases. However, data on releases from individual process units are limited in favor of data to monitor existing end-of-pipe pollution control requirements. The study's sampling program sought to portray the distribution of releases within the refinery, their management within the refinery, and ultimate releases leaving the refinery. Subsequent tests of blowdown stack and fugitive emissions further improved total release estimates. The initial study estimated that the refinery generates about 25,000 metric tons (t)/year of potential pollutants. Of these, about half are released from the refinery as airborne, waterborne, or land-disposed releases. Airborne releases comprise the majority of releases by mass, about 12,000 t/year. Most of the airborne releases are volatile organic compound hydrocarbons. The inventory sampling project and subsequent work identified differences with Toxic Release Inventory (TRI) values and standard emission factors (AP-42). The inventory and other data provided an opportunity to consider options for, and limitations of, specific pollution prevention or source reduction strategies

  12. Media Literacy in Times of Media Divides

    Directory of Open Access Journals (Sweden)

    Kaja Žuran

    2013-12-01

    Full Text Available We live in a post-modern society, an information society, a society based around knowledge and participation, and above all in a media society. In a media culture where media holds a dominant position, we cannot overlook the emerging idea of a ‘media divide’ within the frame of media education, media literate individuals and the expansion of the traditional concept of media literacy. Firstly, we are in an era of technological revolution, and it is time to consider the meaning and function of media and how we experience it in our everyday life. Secondly, as a society we are subject to intense media invasion and we all need to learn how to use it to our benefit and apply a critical and autonomous perspective towards selecting media content. Otherwise the media divide between the media literate and illiterate will widen; but is there even a chance to overcome the supposed divide between those who are formally media educated and those who are not?

  13. Multi-media pollution prevention: A case study of a refinery

    International Nuclear Information System (INIS)

    Schmitt, R.E.; Podar, M.K.

    1994-01-01

    In late 1989, Amoco Corporation and the United States Environmental Protection Agency began a voluntary, joint project to study pollution prevention opportunities at an industrial facility. Amoco proposed use of its refinery at Yorktown, Virginia, to conduct a multi-media assessment of releases to the environment, then to develop and evaluate options to reduce these releases. A Workgroup composed of state, federal, and Amoco representatives provided oversight to the Project. Monthly Workgroup meetings provided Project oversight, a forum for presentations on different Project components, and an opportunity for informal discussion of different viewpoints about environmental management. The Workgroup identified four objectives for this study: (1) Inventory refinery releases to the environment to define their chemical type, quantity, source, and medium of release; (2) develop options to reduce selected releases identified, as well as rank and prioritize the options based on a variety of criteria and perspectives; (3) identify and evaluate factors as technical, legislative, regulatory, institutional, permitting, and economic, that impede or encourage pollution prevention; and (4) enhance participates' knowledge of refinery and regulatory systems

  14. Effects of reactive oxygen species levels in prepared culture media on embryo development: a comparison of two media.

    Science.gov (United States)

    Shih, Ying-Fu; Lee, Tsung-Hsien; Liu, Chung-Hsien; Tsao, Hui-Mei; Huang, Chun-Chia; Lee, Maw-Sheng

    2014-12-01

    This study determined the correlation between the levels of reactive oxygen species (ROS) in prepared culture media and the early development of human embryos. This was an autocontrolled comparison study. A total of 159 patients undergoing in vitro fertilization/intracytoplasmic sperm injection treatment were recruited in this study. The pH values, osmolarity pressures, and ROS levels of 15 batches of two culture media were measured. Sibling oocytes or embryos from individual patients were randomly assigned to two culture groups with Quinn's Advantage Cleavage and Blastocyst media (QAC/QAB) or GIII series cleavage and blastocyst media (G1.3/G2.3). The difference between the two culture groups was analyzed using one-sample t test. The QAC/QAB and G1.3/G2.3 media exhibited similar pH values and osmolarity pressures. However, the prepared QAC/QAB media were characterized to contain lower amounts of ROS than the G1.3/G2.3 media. Furthermore, the blastocysts that developed under the QAC/QAB media were morphologically superior to those that developed under the G1.3/G2.3 media. The elevated ROS levels in culture media were associated with poor development of blastocyst-stage embryos. Measurement of ROS levels may be a valuable process for medium selection or modification. Copyright © 2014. Published by Elsevier B.V.

  15. Synthetic and Virtual Environmental Media (SAVEM)

    International Nuclear Information System (INIS)

    Booth, F. H. K.; Decker, K. M.; Bath, R. J.; Bottrell, D. W.; Wright, K. L.

    2002-01-01

    The Synthetic and Virtual Environmental Media (SAVEM) Program, developed at the DOE Environmental Measurements Laboratory, responds directly to issues of improved data quality, increased regulatory confidence, analytical laboratory waste minimization, pollution prevention, worker safety/radiation exposure risk reduction, and environmental stewardship. The SAVEM radiochemistry information analysis system uses digitally generated spectra to accurately model gamma-ray emission characteristics of radiological samples. A digital virtual sample can be specified that has the characteristics of any environmental media such as soil, sediment, or vegetation, and which exhibits the spectral characteristics of more than 2,000 gamma-emitting nuclides. The SAVEM system can duplicate the characteristics of 2,361 individual radionuclides with 47,902 gamma lines

  16. Formulation and evaluation of sustained release matrix tablets of pioglitazone hydrochloride using processed Aloe vera mucilage as release modifier

    Directory of Open Access Journals (Sweden)

    Manoj Choudhary

    2015-01-01

    Full Text Available Background: Natural gums and mucilage which hydrates and swells on contact with aqueous media are used as additives in the formulation of hydrophilic drug delivery system. Aim: The purpose of this study was to develop a new monolithic matrix system for complete delivery of Pioglitazone hydrochloride (HCl, in a zero-order manner over an extended time period using processed Aloe vera gel mucilage (PAG as a release modifier. Materials and Methods: The matrices were prepared by dry blending of selected ratios of polymer and ingredients using direct compression technique. Physicochemical properties of dried powdered mucilage of A. vera were studied. Various formulations of pioglitazone HCl and A. vera mucilage were prepared using different drug: Polymer ratios viz., 1:1, 1:2, 1:3, 1:4, 1:5 for PAG by direct compression technique. Results: The formulated matrix tablets were found to have better uniformity of weight and drug content with low statistical deviation. The swelling behavior and in vitro release rate characteristics were also studied. Conclusion: The study proved that the dried A. vera mucilage can be used as a matrix forming material for controlled release of Pioglitazone HCl matrix tablets.

  17. Experimental and Sampling Design for the INL-2 Sample Collection Operational Test

    Energy Technology Data Exchange (ETDEWEB)

    Piepel, Gregory F.; Amidan, Brett G.; Matzke, Brett D.

    2009-02-16

    This report describes the experimental and sampling design developed to assess sampling approaches and methods for detecting contamination in a building and clearing the building for use after decontamination. An Idaho National Laboratory (INL) building will be contaminated with BG (Bacillus globigii, renamed Bacillus atrophaeus), a simulant for Bacillus anthracis (BA). The contamination, sampling, decontamination, and re-sampling will occur per the experimental and sampling design. This INL-2 Sample Collection Operational Test is being planned by the Validated Sampling Plan Working Group (VSPWG). The primary objectives are: 1) Evaluate judgmental and probabilistic sampling for characterization as well as probabilistic and combined (judgment and probabilistic) sampling approaches for clearance, 2) Conduct these evaluations for gradient contamination (from low or moderate down to absent or undetectable) for different initial concentrations of the contaminant, 3) Explore judgment composite sampling approaches to reduce sample numbers, 4) Collect baseline data to serve as an indication of the actual levels of contamination in the tests. A combined judgmental and random (CJR) approach uses Bayesian methodology to combine judgmental and probabilistic samples to make clearance statements of the form "X% confidence that at least Y% of an area does not contain detectable contamination” (X%/Y% clearance statements). The INL-2 experimental design has five test events, which 1) vary the floor of the INL building on which the contaminant will be released, 2) provide for varying the amount of contaminant released to obtain desired concentration gradients, and 3) investigate overt as well as covert release of contaminants. Desirable contaminant gradients would have moderate to low concentrations of contaminant in rooms near the release point, with concentrations down to zero in other rooms. Such gradients would provide a range of contamination levels to challenge the sampling

  18. How do Australian news media depict illicit drug issues? An analysis of print media reporting across and between illicit drugs, 2003-2008.

    Science.gov (United States)

    Hughes, Caitlin Elizabeth; Lancaster, Kari; Spicer, Bridget

    2011-07-01

    Media reporting on illicit issues has been frequently criticised for being sensationalised, biased and narrow. Yet, there have been few broad and systematic analyses of the nature of reporting. Using a large sample and methods commonly adopted in media communications analysis this paper sought to identify the dominant media portrayals used to denote illicit drugs in Australian newspapers and to compare and contrast portrayals across drug types. A retrospective content analysis of Australian print media was carried out over the period 2003-2008 from a sample comprised of 11 newspapers. Articles that contained one or more mention of five different drugs (or derivatives) were identified: cannabis, amphetamines, ecstasy, cocaine and heroin. A sub-sample of 4397 articles was selected for media content analysis (with 2045 selected for full content analysis) and a large number of text elements coded for each. Key elements included topic, explicit or implicit messages about the consequences of drugs/use and three value dimensions: overall tone, whether drugs were portrayed as a crisis issue and moral evaluations of drugs/use. The dominant media portrayals depicted law enforcement or criminal justice action (55%), but most articles were reported in a neutral manner, in the absence of crisis framings. Portrayals differed between drugs, with some containing more narrow frames and more explicit moral evaluations than others. For example, heroin was disproportionately framed as a drug that will lead to legal problems. In contrast, ecstasy and cocaine were much more likely to emphasise health and social problems. Media reporting on illicit drugs is heavily distorted towards crime and deviance framings, but may be less overtly sensationalised, biased and narrowly framed than previously suggested. This is not to suggest there is no sensationalism or imbalance, but this appears more associated with particular drug types and episodes of heightened public concern. Copyright © 2011

  19. Pore-Scale Investigation of Micron-Size Polyacrylamide Elastic Microspheres (MPEMs) Transport and Retention in Saturated Porous Media

    KAUST Repository

    Yao, Chuanjin

    2014-05-06

    Knowledge of micrometer-size polyacrylamide elastic microsphere (MPEM) transport and retention mechanisms in porous media is essential for the application of MPEMs as a smart sweep improvement and profile modification agent in improving oil recovery. A transparent micromodel packed with translucent quartz sand was constructed and used to investigate the pore-scale transport, surface deposition-release, and plugging deposition-remigration mechanisms of MPEMs in porous media. The results indicate that the combination of colloidal and hydrodynamic forces controls the deposition and release of MPEMs on pore-surfaces; the reduction of fluid salinity and the increase of Darcy velocity are beneficial to the MPEM release from pore-surfaces; the hydrodynamic forces also influence the remigration of MPEMs in pore-throats. MPEMs can plug pore-throats through the mechanisms of capture-plugging, superposition-plugging, and bridge-plugging, which produces resistance to water flow; the interception with MPEM particulate filters occurring in the interior of porous media can enhance the plugging effect of MPEMs; while the interception with MPEM particulate filters occurring at the surface of low-permeability layer can prevent the low-permeability layer from being damaged by MPEMs. MPEMs can remigrate in pore-throats depending on their elasticity through four steps of capture-plugging, elastic deformation, steady migration, and deformation recovery. © 2014 American Chemical Society.

  20. [Chronic otitis mediaChronic Otitis Media].

    Science.gov (United States)

    Kohles, N; Schulz, T; Eßer, D

    2015-11-01

    There are 2 different kinds of chronic otitis media: Otitis media chronica mesotympanalis and otitis media chronica epitympanalis (cholesteatoma). The incidence of chronic otitis media as reported in literature differs in a wide range. The incidence rates vary between 0.45 and 46%. Both, otitis media chronica mesotympanalis and cholesteatoma, lead to eardrum perforation due to lengthy and recurring inflammations. Furthermore, chronic otitis media is characterized by frequently recurring otorrhea and conductive hearing loss. Georg Thieme Verlag KG Stuttgart · New York.

  1. Passive sampling of DDT, DDE and DDD in sediments: accounting for degradation processes with reaction-diffusion modeling.

    Science.gov (United States)

    Tcaciuc, A Patricia; Borrelli, Raffaella; Zaninetta, Luciano M; Gschwend, Philip M

    2018-01-24

    Passive sampling is becoming a widely used tool for assessing freely dissolved concentrations of hydrophobic organic contaminants in environmental media. For certain media and target analytes, the time to reach equilibrium exceeds the deployment time, and in such cases, the loss of performance reference compounds (PRCs), loaded in the sampler before deployment, is one of the common ways used to assess the fractional equilibration of target analytes. The key assumption behind the use of PRCs is that their release is solely diffusion driven. But in this work, we show that PRC transformations in the sediment can have a measurable impact on the PRC releases and even allow estimation of that compound's transformation rate in the environment of interest. We found that in both field and lab incubations, the loss of the 13 C 2,4'-DDT PRC from a polyethylene (PE) passive sampler deployed at the sediment-water interface was accelerated compared to the loss of other PRCs ( 13 C-labeled PCBs, 13 C-labeled DDE and DDD). The DDT PRC loss was also accompanied by accumulation in the PE of its degradation product, 13 C 2,4'-DDD. Using a 1D reaction-diffusion model, we deduced the in situ degradation rates of DDT from the measured PRC loss. The in situ degradation rates increased with depth into the sediment bed (0.14 d -1 at 0-10 cm and 1.4 d -1 at 30-40 cm) and although they could not be independently validated, these rates compared favorably with literature values. This work shows that passive sampling users should be cautious when choosing PRCs, as degradation processes can affect some PRC's releases from the passive sampler. More importantly, this work opens up the opportunity for novel applications of passive samplers, particularly with regard to investigating in situ degradation rates, pathways, and products for both legacy and emerging contaminants. However, further work is needed to confirm that the rates deduced from model fitting of PRC loss are a true reflection of DDT

  2. Comparison of human dermal fibroblasts (HDFs) growth rate in culture media supplemented with or without basic fibroblast growth factor (bFGF).

    Science.gov (United States)

    Abdian, Narges; Ghasemi-Dehkordi, Payam; Hashemzadeh-Chaleshtori, Morteza; Ganji-Arjenaki, Mahbobe; Doosti, Abbas; Amiri, Beheshteh

    2015-12-01

    Basic fibroblast growth factor (bFGF or FGF-2) is a member of the FGF family secreted by different kinds of cells like HDFs and it is an important nutritional factor for cell growth and differentiation. The HDFs release bFGF in culture media at very low. The present study aims to investigate the HDFs growth rate in culture media supplemented either with or without bFGF. In brief, HDFs were isolated from human foreskin sample and were cultured in vitro in media containing bFGF and lack of this factor. The cells growth rate was calculated by trypan blue. The karyotyping was performed using G-banding to investigate the chromosomal abnormality of HDFs in both groups. Total RNA of each groups were extracted and cDNA samples were synthesized then, real-time Q-PCR was used to measure the expression level of p27kip1 and cyclin D1 genes normalized to internal control gene (GAPDH). The karyotype analysis showed that HDFs cultured in media or without bFGF had normal karyotype (46 chromosomes, XY) and chromosomal abnormalities were not observed. The cell growth rates in both groups were normal with proliferated exponentially but the slope of growth curve in HDFs cultured in media containing bFGF was increased. Karyotyp test showed that bFGF does not affect on cytogenetic stability of cells. The survey of p27kip1 and cyclin D1 genes by real-time Q-PCR showed that the expression level of these genes were up-regulated when adding bFGF in culture media (p culture media with growth factor like bFGF could enhance the proliferation and differentiation capacity of cells and improve cells growth rate. Similarly, fibroblast growth factors did not induce any chromosomal abnormality in cells. Furthermore, in HDFs cultured in bFGF supplemented media, the p27kip1 and cyclin D1 genes were up-regulated and suggesting an important role for bFGF in cell-cycle regulation and progression and fibroblast division stimulation. It also suggests that the effects of bFGF on different cell types with

  3. Effect of thermocycling on nickel release from orthodontic arch wires: an in vitro study.

    Science.gov (United States)

    Sheibaninia, Ahmad

    2014-12-01

    The amount of daily intake of metals from orthodontic appliances over time is a matter of great concern. Nickel results in one of the most common metal-induced allergic contact dermatitis in humans; it produces more allergic reactions than all the other metals combined together. The purpose of this study was to evaluate the effects of thermocycling on the nickel release from orthodontic arch wires stored in artificial saliva with different pH values. Forty new wire pieces were selected. Each wire piece was placed in a special capillary Pyrex tube filled with artificial saliva, which was sealed and immersed in deionized water at 37 °C. The samples were divided into four groups of ten. Group I received no treatment; group II was subjected to thermocycling. The pH of storage in groups III and IV was reduced to 4.5, and group IV was subjected to thermocycling. Thermocycling was carried out between 5 and 55 °C for 500 cycles. The release of nickel ions was statistically analyzed by two-way ANOVA for the effects of two variables: pH and thermocycling. The interaction between pH and thermocycling was found to be statistically significant (F = 12.127, P = 0.001). Two-way ANOVA showed that different storage media or pH and thermocycling had a significant effect on the nickel release (F = 52.812, P nickel from orthodontic wires, while thermocycling is clearly the dominant factor.

  4. The release behavior and kinetic evaluation of tramadol HCl from chemically cross linked Ter polymeric hydrogels.

    Science.gov (United States)

    Malana, Muhammad A; Zohra, Rubab

    2013-01-18

    Hydrogels, being stimuli responsive are considered to be effective for targeted and sustained drug delivery. The main purpose for this work was to study the release behavior and kinetic evaluation of Tramadol HCl from chemically cross linked ter polymeric hydrogels. Ter-polymers of methacrylate, vinyl acetate and acrylic acid cross linked with ethylene glycol dimethacrylate (EGDMA) were prepared by free radical polymerization. The drug release rates, dynamic swelling behavior and pH sensitivity of hydrogels ranging in composition from 1-10 mol% EGDMA were studied. Tramadol HCl was used as model drug substance. The release behavior was investigated at pH 8 where all formulations exhibited non-Fickian diffusion mechanism. Absorbency was found to be more than 99% indicating good drug loading capability of these hydrogels towards the selected drug substance. Formulations designed with increasing amounts of EGDMA had a decreased equilibrium media content as well as media penetrating velocity and thus exhibited a slower drug release rate. Fitting of release data to different kinetic models indicate that the kinetic order shifts from the first to zero order as the concentration of drug was increased in the medium, showing gradual independency of drug release towards its concentration. Formulations with low drug content showed best fitness with Higuchi model whereas those with higher concentration of drug followed Hixson-Crowell model with better correlation values indicating that the drug release from these formulations depends more on change in surface area and diameter of tablets than that on concentration of the drug. Release exponent (n) derived from Korse-Meyer Peppas equation implied that the release of Tramadol HCl from these formulations was generally non-Fickian (n > 0.5 > 1) showing swelling controlled mechanism. The mechanical strength and controlled release capability of the systems indicate that these co-polymeric hydrogels have a great potential to

  5. Characteristics of nurses who use social media.

    Science.gov (United States)

    Kung, Ying Mai; Oh, Sanghee

    2014-02-01

    Social media are changing the ways people communicate and influencing their approaches to meeting their healthcare needs. The Institute of Medicine recommends utilization of information technologies to improve the delivery of patient-centered care. Little is known about how nurses have adopted the use of social media, however. The researchers conducted an online survey to provide a preliminary review of the characteristics of nurses who do and do not use social media. Also, nurses' preferences for using six different types of social media were analyzed and reported. Nurses from 43 states participated in this study, and the sample represented mostly advanced practice nurses who utilized the Internet regularly and confidently. About 94% of the participants indicated that they use social media, whereas fewer than 1% of the participants reported that they do not know how to use social media. Among those who use social media, social networking sites (90.33%) and podcasts (76.24%) were the most popular, followed by social question and asking sites (37.86%), blogs (31.85%), Twitter (19.06%), and SlideShare (9.92%). Social media can be a powerful tool to reach an intended audience quickly and globally. More research is needed to understand how nurses utilize social media to improve the delivery of patient-centered care.

  6. [State school children's opinions regarding violence in the media].

    Science.gov (United States)

    Piedrahita S, Laura E

    2009-01-01

    To describe the opinion of schoolage children, from a public school, regarding the violence they perceive in the media. Descriptive-exploratory research with a sample, selected according to the child's age in a public school. Quantitative data were collected. There were found common issues related to the child's opinion about the violence present in the media such as frequent exposure to the media violence and lack of parental supervision. Social context and constant exposure to the media violence affect the children's opinion about the violence phenomenon and their predisposition to it.

  7. Media Substitution in Advertising: A Spirited Case Study

    OpenAIRE

    Mark W. Frank

    2006-01-01

    This paper uses an unusually rich sample of liquor brands in the U.S. over the period 1994 to 2004 to test substitutability of advertising media. The liquor industry in the U.S. has experienced a substantial increase in case sales and advertising expenditures since the mid-1990s, raising numerous public policy concerns. Moreover, the mix of advertising media used by liquor brands also changed substantially following the industry’s decision in 1996 to begin using radio and television media. We...

  8. Social media as a recruitment strategy

    DEFF Research Database (Denmark)

    Wilson, Rhonda Lynne; Usher, Kim

    2017-01-01

    the research project to potential participants requires a targeted approach, so that the participants will contribute to a data set that is sufficiently representative and analysis will elicit answers to the research questions. Societal changes in communication patterns and in media consumption have led......: Recruitment to a research study requires a strategy that matches the dynamics of the communication media used by potential participants. Nurse researchers need to be adept in the use of social media applied to health research contexts to ensure that data sets obtain representative samples and to reveal...... trustworthy, reliable, dependable and valid evidence to support clinical research and practice. IMPLICATIONS FOR PRACTICE: The general popularity of social media has led to the public expectation that health information, and in some cases treatment, will be available online. Such a change in communication...

  9. The Strategic Combination of Open-Access Peer-Review, Mainstream Media and Social Media to Improve Public Climate Literacy (Invited)

    Science.gov (United States)

    Cook, J.; Nuccitelli, D. A.; Jacobs, P.

    2013-12-01

    The Skeptical Science website began in 2007, with the goal of refuting climate misinformation with peer-reviewed science. It achieved this by embracing a diversity of message formats and delivery methods. Myth rebuttals are available at beginner, intermediate and advanced levels, spanning from long, technical treatments to tweetable one-liners. Content has been translated into 20 different languages and made available via the web, an iPhone app and books while adopted by third parties in textbooks, university and MOOC curricula, books, Senate testimonies and TV documentaries. While social media has been a fruitful medium, we experimented with a new model in 2013, employing the strategic combination of open-access peer-review, mainstream media outreach and social media marketing. This strategy was adopted with the release of a paper quantifying the level of scientific consensus in published climate papers, resulting in broad mainstream media attention as well as acknowledgement from key public figures such as Al Gore, the UK Minister for Energy Edward Davey and President Obama. Our approach was informed by psychological research into both the importance of scientific consensus and how to reduce the influence of misconceptions. While multiple methods of delivery are important, equally important is the construction of the messages themselves. I will examine the science of crafting compelling messages and how combination with diverse message delivery can lead to impactful outcomes.

  10. Covert Marketing: A Virtual Media Communication Vehicle

    Directory of Open Access Journals (Sweden)

    Pradeep Kautish

    2010-03-01

    Full Text Available Consumers' suspicion towards traditional marketing techniques, led marketers to try the virtual media communication form called disguise advertising as other forms of messages. The examples include making advertisements resemble news items (Aditya 2001; Levine 1993; Richards 1992, the infomercials in the '90s that disguise advertising as TV programs (Levine 1993; Lacher and Rotfeld 1994, making celebrities use the products in their real lives or in films (Aditya2001, feeding media information using public relations (PR activities like brib- ing journalists with gifts and making TV stations use the footages from press releases (Gillin 2006. Because of the prevalence of virtual media, the marketing practices that conceal the real sources (marketers with disguised sources haveposed both ethical and policy concerns. This article proposed a new typology that covered the comprehensive scope of disguised marketing practices, discussed the deceptive nature of this marketing technique from the consumer behavioral view- points, and conducted a 2 x 3 experiment to test the hypothesized relationships.The results suggest that an implicit message, disguised source’s preference, is likely to be conveyed in covert marketing and thus results in high a deceptive tendency.

  11. Use of social media by airports

    OpenAIRE

    Halpern, Nigel

    2012-01-01

    Purpose: This study investigates use of social media by airports according to geographical location of the airport, airport size, and airport ownership and operation. Design/methodology/approach: The study is based on a content analysis of airport websites. The sample consists of 1559 airports worldwide that are members of Airports Council International (ACI). Findings: Almost one-fifth of airports use at least one type of social media; 13% use Facebook, 12% use Twitter, 7% use LinkedIn...

  12. Bedroom media: One risk factor for development.

    Science.gov (United States)

    Gentile, Douglas A; Berch, Olivia N; Choo, Hyekyung; Khoo, Angeline; Walsh, David A

    2017-12-01

    Mass media have numerous effects on children, ranging from influencing school performance to increased or reduced aggression. What we do not know, however, is how media availability in the bedroom moderates these effects. Although several researchers have suggested that bedroom media may influence outcomes by displacing other activities (the displacement hypothesis) or by changing the content of media consumed (the content hypothesis), these have rarely been tested directly. This study tested both hypotheses using several outcomes that are associated with bedroom media and some of the underlying mediating mechanisms. The hypotheses were tested using 3 longitudinal samples of varying methods, age, duration, and country. The results indicate that children who have bedroom media are likely to watch larger amounts of screen time which displaced important activities, such as reading and sleeping, which mediated later negative outcomes such as poor school performance. Bedroom media also influence risk for obesity and video game addiction. Children with bedroom media are also likely to be exposed to more media violence. The violent content increased normative beliefs about aggression, which increased physical aggression, providing support for the content hypothesis. This study demonstrates that media can have effects not just from what they show, but also because of what children are not exposed to. Bedroom media are therefore a robust risk factor for several aspects of child development. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Formulation and characterization of modified release tablets containing isoniazid using swellable polymers.

    Science.gov (United States)

    Akhtar, M F; Rabbani, M; Sharif, A; Akhtar, B; Saleem, A; Murtaza, G

    2011-01-01

    The aim of this work was to develop swellable modified release (MR) isoniazid tablets using different combinations of polyvinyl acetate (PVAc) and sodium-carboxymethylcellulose (Na-CMC). Granules were prepared by moist granulation technique and then compressed into tablets. In vitro release studies for 12 hr were carried out in dissolution media of varying pH i.e. pH 1.2, 4.5, 7.0 and 7.5. Tablets of all formulations were found to be of good physical quality with respect to appearance (width and thickness), content uniformity, hardness, weight variation and friability. In vitro release data showed that increasing total polymer content resulted in more retarding effect. Formulation with 35% polymer content exhibited zero order release profile and it released 35% of the drug in first hr, later on, controlled drug release was observed upto the 12(th) hour. Formulations with PVAc to Na-CMC ratio 20:80 exhibited zero order release pattern at levels of studied concentrations, which suggested that this combination can be used to formulate zero order release tablets of water soluble drugs like isoniazid. Korsmeyer-Peppas modeling of drug release showed that non-Fickian transport is the primary mechanism of isoniazid release from PVAc and Na-CMC based tablets. The value of mean dissolution time decreased with the increase in the release rate of drug clearly showing the retarding behavior of the swellable polymers. The application of a mixture of PVAc to Na-CMC in a specific ratio may be feasible to formulate zero order release tablets of water soluble drugs like isoniazid.

  14. Release from the Crabtree effect by hypoxic cell radiosensitizers

    International Nuclear Information System (INIS)

    Mustea, I.; Bara, A.

    1979-01-01

    The Crabtree effect can be observed when the 0 2 consumption of tumour cells or of mammalian cells grown in culture is measured in physiological medium containing glucose. The effect of 2 hypoxic cell radiosensitizers, misonidazole and NDPP, on the 0 2 consumption of Ehrlich ascites tumour cells was compared in media with and without glucose. A stimulatory effect on 0 2 consumption was found for 5-20 mM misonidazole as well as for 0.5mM NDPP, both in media containing 10 -2 M glucose. Thus glucose induced a Crabtree effect in Ehrlich tumour cells, expressed as 38-45% inhibition of 0 2 consumption relative to that in the same medium without glucose. The stimulatory effect of misonidazole and NDPP on 0 2 utilization in medium with glucose undoubtedly appeared as a release from the Crabtree effect. (author)

  15. Filter media properties of mineral fibres produced by plasma spray.

    Science.gov (United States)

    Prasauskas, Tadas; Matulevicius, Jonas; Kliucininkas, Linas; Krugly, Edvinas; Valincius, Vitas; Martuzevicius, Dainius

    2016-01-01

    The purpose of this study was to determine the properties of fibrous gas filtration media produced from mineral zeolite. Fibres were generated by direct current plasma spray. The paper characterizes morphology, chemical composition, geometrical structure of elementary fibres, and thermal resistance, as well as the filtration properties of fibre media. The diameter of the produced elementary fibres ranged from 0.17 to 0.90 μm and the length ranged from 0.025 to 5.1 mm. The release of fibres from the media in the air stream was noticed, but it was minimized by hot-pressing the formed fibre mats. The fibres kept their properties up to the temperature of 956°C, while further increase in temperature resulted in the filter media becoming shrunk and brittle. The filtration efficiency of the prepared filter mats ranged from 95.34% to 99.99% for aerosol particles ranging in a size between 0.03 and 10.0 μm. Unprocessed fibre media showed the highest filtration efficiency when filtering aerosol particles smaller than 0.1 µm. Hot-pressed filters were characterized by the highest quality factor values, ranging from 0.021 to 0.064 Pa(-1) (average value 0.034 Pa(-1)).

  16. Nanostructural drug-inorganic clay composites: Structure, thermal property and in vitro release of captopril-intercalated Mg-Al-layered double hydroxides

    International Nuclear Information System (INIS)

    Zhang Hui; Zou Kang; Guo Shaohuan; Duan Xue

    2006-01-01

    A nanostructural drug-inorganic clay composite involving a pharmaceutically active compound captopril (Cpl) intercalated Mg-Al-layered double hydroxides (Cpl-LDHs) with Mg/Al molar ratio of 2.06 has been assembled by coprecipitation method. Powder X-ray diffraction (XRD), Fourier transform infrared spectra (FT-IR) and Raman spectra analysis indicate a successful intercalation of Cpl between the layers with a vertical orientation of Cpl disulphide-containing S-S linkage. SEM photo indicates that as-synthesized Cpl-LDHs possess compact and non-porous structure with approximately and linked elliptical shape particles of ca. 50 nm. TG-DTA analyses suggest that the thermal stability of intercalated organic species is largely enhanced due to host-guest interaction involving the hydrogen bond compared to pure form before intercalation. The in vitro release studies show that both the release rate and release percentages markedly decrease with increasing pH from 4.60 to 7.45 due to possible change of release mechanism during the release process. The kinetic simulation for the release data, and XRD and FT-IR analyses for samples recovered from release media indicate that the dissolution mechanism is mainly responsible for the release behaviour of Cpl-LDHs at pH 4.60, while the ion-exchange one is responsible for that at pH 7.45. - Graphical abstract: Based on XRD, FT-IR and Raman spectra analyses, it is suggested that captopril (Cpl) exists as its disulphide metabolites in the interlayer of Mg-Al-LDHs via hydrogen bonding between guest carboxylate function and hydroxyl group of the host layers. A schematic supramolecular structure of Cpl intercalates involving a vertical orientation of Cpl disulphide-containing S-S bond between the layers with carboxylate anions pointing to both hydroxide layers is presented

  17. The replacement of serum by hormones in cell culture media.

    Science.gov (United States)

    Sato, G; Hayashi, I

    1976-12-01

    The replacement of serum by hormones in cell culture media. (Reemplazo del suero por hormonas en el medio de cultivo de células). Arch. Biol. Med. Exper. 10: 120-121, 1976. The serum used in cell culture media can be replaced by a mixture of hormones and some accesory blood factors. The pituitary cell line GH3 can be grown in a medium in which serum is replaced by triiodothyronine, transferrin, parathormone, tyrotrophin releasing hormone and somatomedins. Hela and BHK cell strains can also be grown in serum free medium supplemented with hormones. Each cell type appears to have different hormonal requirements yet it may found that some hormones are required for most cell types.

  18. Assessment of drug salt release from solutions, suspensions and in situ suspensions using a rotating dialysis cell

    DEFF Research Database (Denmark)

    Parshad, Henrik; Frydenvang, Karla; Liljefors, Tommy

    2003-01-01

    buffer is used as release media. Generally, the initial release of the drug salt from in situ suspensions occurred faster as compared to conventional suspensions, probably due to incomplete precipitation of the drug salt, and hence formation of supersaturated solutions where the rate of release......A rotating dialysis cell consisting of a small (10 ml) and a large compartment (1000 ml) was used to study the release of drug salt (bupivacaine 9-anthracene carboxylate) from (i). solutions, (ii). suspensions and (iii). in situ formed suspensions. Initial release experiments from suspensions...... indicated that the release of drug salt in deionized water was predominantly limited by the diffusion across the membrane whereas it is essentially dissolution rate controlled in 0.05 M phosphate buffer (pH 7.40). Thus, the in vitro model appears to have a potential in formulation screening when phosphate...

  19. Differential Mobility-Mass Spectrometry Double Spike Isotope Dilution Study of Release of β-Methylaminoalanine and Proteinogenic Amino Acids during Biological Sample Hydrolysis.

    Science.gov (United States)

    Beach, Daniel G; Kerrin, Elliott S; Giddings, Sabrina D; Quilliam, Michael A; McCarron, Pearse

    2018-01-08

    The non-protein amino acid β-methylamino-L-alanine (BMAA) has been linked to neurodegenerative disease and reported throughout the environment. Proposed mechanisms of bioaccumulation, trophic transfer and chronic toxicity of BMAA rely on the hypothesis of protein misincorporation. Poorly selective methods for BMAA analysis have led to controversy. Here, a recently reported highly selective method for BMAA quantitation using hydrophilic interaction liquid chromatography-differential mobility spectrometry-tandem mass spectrometry (HILIC-DMS-MS/MS) is expanded to include proteinogenic amino acids from hydrolyzed biological samples. For BMAA quantitation, we present a double spiking isotope dilution approach using D 3 -BMAA and 13 C 15 N 2 -BMAA. These methods were applied to study release of BMAA during acid hydrolysis under a variety of conditions, revealing that the majority of BMAA can be extracted along with only a small proportion of protein. A time course hydrolysis of BMAA from mussel tissue was carried out to assess the recovery of BMAA during sample preparation. The majority of BMAA measured by typical methods was released before a significant proportion of protein was hydrolyzed. Little change was observed in protein hydrolysis beyond typical hydrolysis times but the concentration of BMAA increased linearly. These findings demonstrate protein misincorporation is not the predominant form of BMAA in cycad and shellfish.

  20. Real time in vitro studies of doxorubicin release from PHEMA nanoparticles

    Directory of Open Access Journals (Sweden)

    Bajpai AK

    2009-10-01

    Full Text Available Abstract Background Many anticancer agents have poor water solubility and therefore the development of novel delivery systems for such molecules has received significant attention. Nanocarriers show great potential in delivering therapeutic agents into the targeted organs or cells and have recently emerged as a promising approach to cancer treatments. The aim of this study was to prepare and use poly-2-hydroxyethyl methacrylate (PHEMA nanoparticles for the controlled release of the anticancer drug doxorubicin. Results PHEMA nanoparticles have been synthesized and characterized using FTIR and scanning electron microscopy (SEM, particle size analysis and surface charge measurements. We also studied the effects of various parameters such as percent loading of drugs, chemical architecture of the nanocarriers, pH, temperature and nature of the release media on the release profiles of the drug. The chemical stability of doxorubicin in PBS was assessed at a range of pH. Conclusion Suspension polymerization of 2-hydroxyethyl methacrylate (HEMA results in the formation of swellable nanoparticles of defined composition. PHEMA nanoparticles can potentially be used for the controlled release of the anticancer drug doxorubicin.

  1. 40 CFR 1065.595 - PM sample post-conditioning and total weighing.

    Science.gov (United States)

    2010-07-01

    ... minutes before weighing. Note that 400 µg on sample media (e.g., filters) is an approximate net mass of 0... the procedures in § 1065.590(f) through (i) to determine post-test mass of the sample media (e.g., filters). (g) Subtract each buoyancy-corrected tare mass of the sample medium (e.g., filter) from its...

  2. Tritium release from Li{sub 4}SiO{sub 4} ceramic pebbles in high magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Ran, Guangming [School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230027 (China); Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900 (China); Xiao, Chengjian; Chen, Xiaojun; Gong, Yu; Zhao, Linjie [Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, Mianyang 621900 (China); Wang, Xiaolin [School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230027 (China); China Academy of Engineering Physics, Mianyang 621900 (China)

    2015-12-15

    Highlights: • Behavior of tritium release from Li{sub 4}SiO{sub 4} pebbles in MF up to 7 T was investigated. • The MF effect on tritium release is not significant according to the TPD results. • Tritium release from the BIG sample is much easier than that from the SMALL sample. • The MF effect on tritium diffusion was probably weakened by surface desorption. - Abstract: The behavior of tritium release from Li{sub 4}SiO{sub 4} ceramic pebbles in high magnetic field (MF) was investigated by temperature programmed desorption (TPD). Two batches of Li{sub 4}SiO{sub 4} pebbles produced by wet method were used as the experimental samples, one batch with an average pebble diameter of 0.8 mm (the SMALL samples), and the other 1.2 mm (the BIG samples). A superconducting magnet was applied to generate MF up to 7 T in the sample area during annealing. For both batches of samples, the tritium release curves within and without MF showed very similar characteristics, indicating that the effect of high MF on tritium release behavior is not significant. The tritium release peaks for the BIG samples were observed at much lower temperatures than that for the SMALL samples, even though the grain sizes of the BIG samples are much bigger than that of the SMALL samples. It is considered that surface desorption process dominates the overall tritium release behavior in this work, which probably weakened the MF effect.

  3. Simplified analytical model to simulate radionuclide release from radioactive waste trenches

    International Nuclear Information System (INIS)

    Sa, Bernardete Lemes Vieira de

    2001-01-01

    In order to evaluate postclosure off-site doses from low-level radioactive waste disposal facilities, a computer code was developed to simulate the radionuclide released from waste form, transport through vadose zone and transport in the saturated zone. This paper describes the methodology used to model these process. The radionuclide released from the waste is calculated using a model based on first order kinetics and the transport through porous media was determined using semi-analytical solution of the mass transport equation, considering the limiting case of unidirectional convective transport with three-dimensional dispersion in an isotropic medium. The results obtained in this work were compared with other codes, showing good agreement. (author)

  4. OPM: The Open Porous Media Initiative

    Science.gov (United States)

    Flemisch, B.; Flornes, K. M.; Lie, K.; Rasmussen, A.

    2011-12-01

    The principal objective of the Open Porous Media (OPM) initiative is to develop a simulation suite that is capable of modeling industrially and scientifically relevant flow and transport processes in porous media and bridge the gap between the different application areas of porous media modeling, including reservoir mechanics, CO2 sequestration, biological systems, and product development of engineered media. The OPM initiative will provide a long-lasting, efficient, and well-maintained open-source software for flow and transport in porous media built on modern software principles. The suite is released under the GNU General Public License (GPL). Our motivation is to provide a means to unite industry and public research on simulation of flow and transport in porous media. For academic users, we seek to provide a software infrastructure that facilitates testing of new ideas on models with industry-standard complexity, while at the same time giving the researcher control over discretization and solvers. Similarly, we aim to accelerate the technology transfer from academic institutions to professional companies by making new research results available as free software of professional standard. The OPM initiative is currently supported by six research groups in Norway and Germany and funded by existing grants from public research agencies as well as from Statoil Petroleum and Total E&P Norge. However, a full-scale development of the OPM initiative requires substantially more funding and involvement of more research groups and potential end users. In this talk, we will provide an overview of the current activities in the OPM initiative. Special emphasis will be given to the demonstration of the synergies achieved by combining the strengths of individual open-source software components. In particular, a new fully implicit solver developed within the DUNE-based simulator DuMux could be enhanced by the ability to read industry-standard Eclipse input files and to run on

  5. Releasing an album in the US : Entering the Foreign Market with an Independent Label Resources

    OpenAIRE

    Sikiö, Ville-Mikko

    2013-01-01

    The objective of the project thesis was to inspect the releasing of an album of a Finnish artist with independent record label resources in the North American market. The focus of the thesis was on the marketing and promotion of an artist with an independent label’s limited resources, and on how the foreign market, its operators and media should be approached. As a case the thesis used the singer-songwriter Mirel Wagner’s debut album and its marketing and the promotion for the release in the ...

  6. PR Crisis Melalui Media Sosial

    Directory of Open Access Journals (Sweden)

    Gladys Carlina

    2017-07-01

    Full Text Available The background of this research is communication, new media, PR and PR Crisis. Fourth of this background has a close relationship, starting from communication, human in everyday life would require communication to receive and convey information, human can not be released from human life. The advancement of the times and the development of technology, causing people to communicate easily and the development of this era caused a new challenge for the PR and PR Crisis of a company, they should be able to maintain a positive image of the company in the minds of people. In this study using descriptive qualitative methodology, it contains many writings and drawings compared to the numbers. The purpose of this research is to know the strategy used by Pizza Hut in dealing with the issue of expired food. Penelitin results, social media is very positive impact on Pizza Hut in the recovery of food issues expired. The strategy used by the Pizza Hut Crisis PR is to utilize social media. Visible from the issue of expired food that disappeared in public and Pizza Hut restaurant until now crowded visited. Latar belakang dari penelitian ini yaitu komunikasi, media baru, PR dan PR Krisis. Keempat dari latar belakang ini mempunyai hubungan yang erat, dimulai dari komunikasi, manusia di dalam kehidupan sehari-hari tentunya memerlukan komunikasi untuk menerima dan menyampaikan informasi, manusia tidak bisa dilepaskan dari kehidupan manusia. Majunya perkembangan zaman dan perkembangan teknologi, menyebabkan manusia melakukan komunikasi dengan mudah dan perkembangan zaman ini menyebabkan adanya tantangan baru bagi para PR dan PR Krisis sebuah perusahaan, mereka harus bisa mempertahankan citra positif perusahaan di benak masyarakat. Dalam penelitian ini menggunakan metodologi kualitatif deksriptif, memuat banyak tulisan dan gambar dibandingkan angka-angka. Tujuan dari penelitian ini untuk mengetahui strategi yang digunakan oleh Pizza Hut dalam menangani isu makanan

  7. A poly({epsilon}-caprolactone) device for sustained release of an anti-glaucoma drug

    Energy Technology Data Exchange (ETDEWEB)

    Natu, Madalina V; De Sousa, HermInio C; Gil, M H [Department of Chemical Engineering, University of Coimbra, Polo II, Pinhal de Marrocos, 3030-290, Coimbra (Portugal); Gaspar, Manuel N; Fontes Ribeiro, Carlos A [Institute of Pharmacology and Experimental Therapeutics, University of Coimbra, Azinhaga de Santa Comba, Celas, 3000-354, Coimbra (Portugal); Correia, IlIdio J; Silva, Daniela, E-mail: hgil@eq.uc.pt [Centro de Investigacao em Ciencias da Saude, Faculdade de Ciencias da Saude, Universidade da Beira Interior, Covilha (Portugal)

    2011-04-15

    Implantable dorzolamide-loaded discs were prepared by blending poly({epsilon}-caprolactone), PCL, with poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), Lu. By blending, crystallinity, water uptake and mass loss were modified relative to the pure polymers. Burst was diminished by coating the discs with a PCL shell. All samples presented burst release except PCL-coated samples that showed controlled release during 18 days. For PCL-coated samples, barrier control of diffusion coupled with partition control from the core slowed down the release, while for 50/50 Lu/PCL-coated samples, the enhancement in the porosity of the core diminished partition control of drug release. Nonlinear regression analysis suggested that a degradation model fully describes the release curve considering a triphasic release mechanism: the instantaneous diffusion (burst), diffusion and polymer degradation stages. The MTT test indicated that the materials are not cytotoxic for corneal endothelial cells. A good in vitro-in vivo correlation was obtained, with similar amounts of drug released in vitro and in vivo. The discs decreased intraocular pressure (IOP) in normotensive rabbit eyes by 13.0% during 10 days for PCL-coated and by 13.0% during 4 days for 50/50 Lu/PCL-coated samples. The percentages of IOP decrease are similar to those obtained by dorzolamide eyedrop instillation (11.0%).

  8. Managing Media: Segmenting Media Through Consumer Expectancies

    Directory of Open Access Journals (Sweden)

    Matt Eastin

    2014-04-01

    Full Text Available It has long been understood that consumers are motivated to media differently. However, given the lack of comparative model analysis, this assumption is without empirical validation, and thus, the orientation of segmentation from a media management perspective is without motivational grounds. Thus, evolving the literature on media consumption, the current study develops and compares models of media segmentation within the context of use. From this study, six models of media expectancies were constructed so that motivational differences between media (i.e., local and national newspapers, network and cable television, radio, and Internet could be observed. Utilizing higher order statistical analyses the data indicates differences across a model comparison approach for media motivations. Furthermore, these differences vary across numerous demographic factors. Results afford theoretical advancement within the literature of consumer media consumption as well as provide media planners’ insight into consumer choices.

  9. Sexualizing Media Use and Self-Objectification

    Science.gov (United States)

    Karsay, Kathrin; Knoll, Johannes; Matthes, Jörg

    2017-01-01

    Objectification theorists suggest that exposure to sexualizing media increases self-objectification among individuals. Correlational and experimental research examining this relation has received growing attention. The aim of this meta-analysis was to investigate the influence of sexualizing media use on self-objectification among women and men. For this purpose, we analyzed 54 papers yielding 50 independent studies and 261 effect sizes. The data revealed a positive, moderate effect of sexualizing media on self-objectification (r = .19). The effect was significant and robust, 95% CI [.15, .23], p media type, suggesting that the use of video games and/or online media led to stronger self-objectification effects when compared to television use. Other sample characteristics or study characteristics did not moderate the overall effect. Thus, our findings highlight the importance of sexualizing media exposure on women’s and men’s objectified self-concept. We discuss future research directions and implications for practice. We hope that the article will stimulate researchers in their future work to address the research gaps outlined here. Moreover, we hope that the findings will encourage practitioners and parents to reflect on the role of the use of sexualizing media in the development of individuals’ self-objectification. Additional online materials for this article are available on PWQ’s website at http://journals.sagepub.com/doi/suppl10.1177/0361684317743019 PMID:29527090

  10. Friezen op sosjale media : Rapportaazje ûndersyk Taalfitaliteit II

    NARCIS (Netherlands)

    Jongbloed-Faber, L.

    2015-01-01

    In 2014, over 1,200 Frisians (aged 15 – 94 years old) participated in an online survey about language use on social media. As we asked people to participate through social and traditional media, the data are a snowball sample and are not representative. Also the Frisian-speaking adults use Frisian

  11. Mass-media - Partener în realizarea formelor comunicării publice

    Directory of Open Access Journals (Sweden)

    Corina RĂDULESCU

    2012-06-01

    Full Text Available In the Romanian public sphere a fault line is noticeable between the two pillars of public communication: the citizen and the public authorities, despite the fact that we live in a time of extensive development of communication means and also that, in its essence, public communication means more than simply to inform the public. Also, in the economy of the process of building the public immage of a public institution, all registers of public communication bring their contribution, but external communication, especially media relations, are of strategic importance in realizing this goal. From both perspectives, the present paper shows that there is a large diversity of instruments available to public institutions in working with the media (press release, press conference, interview, etc. and that the media can fully contribute to the realization of all forms of public communication, provided there is instututional willingness for this matter. To conclude, between any public institution and the media there must exist professional colaboration relations, based on mutual respect.

  12. Media and Australia's replacement reactor project

    International Nuclear Information System (INIS)

    Keenan, Pamela

    2001-01-01

    . In dealing with the journalists' exaggerations, ANSTO was placed in a reactionary position. A few features of our communications strategy which have proved successful include Letters to the Editor, retractions, media briefings, reissue of media releases, newsletters, direct mail and staff information updates complete the suite of ideas used

  13. Comparison of culture media for the laboratory diagnosis of chancroid.

    Science.gov (United States)

    Pillay, A; Hoosen, A A; Loykissoonlal, D; Glock, C; Odhav, B; Sturm, A W

    1998-11-01

    Seven different agar-based media were compared to determine the optimal set of culture media for primary isolation of Haemophilus ducreyi. Also, a new method for sampling genital ulcers -- with a disposable sterile plastic loop -- and processing specimens that provides a standardised inoculum for culture of H. ducreyi on various media is described. A total of 202 patients with genital ulcer disease was enrolled in this study. A sterile swab or plastic loop was used to sample the base of the ulcers and ulcer material was suspended in sterile phosphate-buffered saline. A 100-microl sample of this suspension was mixed with an equal volume of tryptic soy broth containing IsoVitaleX and centrifuged for 1 min. This suspension was used to inoculate the different media. Plates were incubated at 33 degrees C in micro-aerophilic conditions and examined for growth of H. ducreyi after 48 h. Of the 202 specimens, 77 (38.1%) were culture positive for H. ducreyi. None of the agar bases supported the growth of all H. ducreyi strains. Based on this observation, we recommend the universal use of Mueller-Hinton agar base supplemented with chocolate horse blood and IsovitaleX (MH-HBC) and Columbia agar base supplemented with bovine haemoglobin, activated charcoal, fetal calf serum and IsovitaleX (C-HgCh) to enable comparison of prevalence figures for chancroid. In addition, the novel sampling technique described in this study eliminates sampling bias normally associated with genital ulcer specimens.

  14. Effects of environment on the release of Ni, Cr, Fe, and Co from new and recast Ni-Cr alloy.

    Science.gov (United States)

    Oyar, Perihan; Can, Gülşen; Atakol, Orhan

    2014-07-01

    The addition of previously cast alloy to new alloy for economic reasons may increase the release of elements. The purpose of this study was to analyze the effects of the immersion period, immersion media, and addition of previously cast alloy to new alloy on the release of elements. Disk-shaped specimens were prepared from a Ni-Cr alloy (Ni: 61 wt%, Cr: 26 wt%, Mo: 11 wt%, Si: 1.5 wt%, Fe, Ce, Al, and Co alloy (group N) and 50% new/50% recast alloy (group R). After the immersion of the specimens in both NaCl (pH 4) and artificial saliva (pH 6.7) for 3, 7, 14, 30, and 60 days, the release of ions was determined by using atomic absorption spectrometry. Data were analyzed with a 3-way ANOVA (α=.001). The release of Ni was significantly affected by the immersion period, of Ni and Cr by the alloy and media (Palloy (Palloy in artificial saliva was 109.71 for Ni, 6.49 for Cr, 223.22 for Fe, and 29.90 μg/L for Co. The release of Co in NaCl was below the detection limit in both groups. The release of Ni in NaCl and artificial saliva increased with the length of the immersion period in both groups. The release of Cr and Fe was higher in artificial saliva than in NaCl in group R, regardless of the immersion period. The release of Co in NaCl was below the detection limit in both groups. Copyright © 2014 The Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  15. The INC. 500 and social media: Marketing research

    Directory of Open Access Journals (Sweden)

    Nora Ganim Barnes

    2008-07-01

    Full Text Available As a great challenge in communications, social media are widely accepted among the general population. Being very flexible and adaptable, they offer an opportunity of active participation to users, thus representing a public forum. This study presents the resultsof social media acceptance in the business world on a sample of the Inc. 500 companies in the US. The research found that familiarity, the value placed on social media and the use of different forms of social media are all related. These companies know that engaging social media requires education and a change of the management effort. They use them to gather critical strategic information by listening to what is being said about themselves and their competitors in the social media world. The Inc. 500 companies accept social media as a medium. They recognize that the marketplace is movingtheir conversations online and the business world needs to join in. These fast-growing, innovative companies offer us a glimpse of the business future because where they lead, others will certainly follow.

  16. MS-2 and poliovirus transport in porous media: Hydrophobic effects and chemical perturbations

    Science.gov (United States)

    Bales, Roger C.; Li, Shimin; Maguire, Kimberly M.; Yahya, Moyasar T.; Gerba, Charles P.

    1993-04-01

    In a series of pH 7 continuous-flow column experiments, removal of the bacteriophage MS-2 by attachment to silica beads had a strong, systematic dependence on the amount of hydrophobic surface present on the beads. With no hydrophobic surface, removal of phage at pH 5 was much greater than at pH 7. Release of attached phage at both pH values did occur, but was slow; breakthrough curves exhibited tailing. Poliovirus attached to silica beads at pH 5.5 much more than at pH 7.0, and attachment was also slowly reversible. Time scales for phage and poliovinis attachment were of the order of hours. The sticking efficiency factor (α), reflecting microscaie physicochemical influences on virus attachment, was in the range of 0.0007-0.02. Phage release was small but measurable under steady state conditions. Release was enhanced by lowering ionic strength and by introducing beef extract, a high-ionic-strength protein solution. Results show that viruses experience reversible attachment/detachment (sometimes termed sorption), that large chemical perturbations are needed to induce rapid virus detachment, and that viruses should be quite mobile in sandy porous media. Even small amounts of hydrophobic organic material in the porous media (≥0.001%) can retard virus transport.

  17. Determination of metal ions released by stainless steel arch bar into bio-fluids

    Directory of Open Access Journals (Sweden)

    Lori A. Joseph

    2009-04-01

    Full Text Available The amounts of cobalt, iron, manganese, nickel and chromium ions released from new and reused stainless steel arch bar used for maxillomandibular fixation was determined in Hank’s solutions of different hydrogen and chloride ions concentrations, whole blood serum and phosphate buffered saline (PBS in vitro, over a six-week immersion time at 37 oC, by atomic absorption spectrophotometry. The corrosion levels of the wires due to effects of media and incubation times in the bio-fluids were compared by Duncan’s two-way ANOVA (P less than 0.05. Pearson’s correlation was used in establishing relationship in the amounts of metal ions released by new and reused arch bars. The study indicated that the reused wires released more ions than new ones at all time points. The variation of pH and chloride ions of the bio-fluids had a significant effect on the amount of Ni, Mn and Cr ions released. Ageing prior use of arch bars significantly increased Ni ions released into the bio-fluids.

  18. Calculation of tritium release from reactor's stack

    International Nuclear Information System (INIS)

    Akhadi, M.

    1996-01-01

    Method for calculation of tritium release from nuclear to environment has been discussed. Part of gas effluent contain tritium in form of HTO vapor released from reactor's stack was sampled using silica-gel. The silica-gel was put in the water to withdraw HTO vapor absorbed by silica-gel. Tritium concentration in the water was measured by liquid scintillation counter of Aloka LSC-703. Tritium concentration in the gas effluent and total release of tritium from reactor's stack during certain interval time were calculated using simple mathematic formula. This method has examined for calculation of tritium release from JRR-3M's stack of JAERI, Japan. From the calculation it was obtained the value of tritium release as much as 4.63 x 10 11 Bq during one month. (author)

  19. Torsten Almén (1931-2016): the father of non-ionic iodine contrast media.

    Science.gov (United States)

    Nyman, Ulf; Ekberg, Olle; Aspelin, Peter

    2016-09-01

    The Swedish radiologist Torsten Almén is the first clinical radiologist ever to have made a fundamental contribution to intravascular contrast medium design, the development of non-ionic contrast media. He became emotionally triggered by the patients' severe pain each time he injected the ionic "high-osmolar" contrast media when performing peripheral arteriographies in the early 1960s. One day he got a flash of genius that combined the observation of pain, a pathophysiological theory and how to eliminate it with suitable contrast media chemistry. After self-studies in chemistry he developed the concept of iodine contrast media not dissociating into ions in solution to reduce their osmolality and even reach plasma isotonicity. He offered several pharmaceutical companies his concept of mono- and polymeric non-ionic agents but without response, since it was considered against the chemical laws of that time. Contrast media constructed as salts and dissociating into ions in solution was regarded an absolute necessity to achieve high enough water solubility and concentration for diagnostic purposes. Finally a small Norwegian company, Nyegaard & Co., took up his idea 1968 and together they developed the essentially painless "low-osmolar" monomeric non-ionic metrizamide (Amipaque) released in 1974 and iohexol (Omipaque) in 1982 followed by the "iso-osmolar" dimeric non-ionic iodixanol (Visipaque) released in 1993. This has implied a profound paradigm shift with regard to reduction of both hypertonic and chemotoxic side effects, which have been a prerequisite for the today's widespread use of contrast medium-enhanced CT and advanced endovascular interventional techniques even in fragile patients. © The Foundation Acta Radiologica 2016.

  20. Inorganically modified diatomite as a potential prolonged-release drug carrier.

    Science.gov (United States)

    Janićijević, Jelena; Krajišnik, Danina; Calija, Bojan; Dobričić, Vladimir; Daković, Aleksandra; Krstić, Jugoslav; Marković, Marija; Milić, Jela

    2014-09-01

    Inorganic modification of diatomite was performed with the precipitation product of partially neutralized aluminum sulfate solution at three different mass ratios. The starting and the modified diatomites were characterized by SEM-EDS, FTIR, thermal analysis and zeta potential measurements and evaluated for drug loading capacity in adsorption batch experiments using diclofenac sodium (DS) as a model drug. In vitro drug release studies were performed in phosphate buffer pH6.8 from comprimates containing: the drug adsorbed onto the selected modified diatomite sample (DAMD), physical mixture of the drug with the selected modified diatomite sample (PMDMD) and physical mixture of the drug with the starting diatomite (PMDD). In vivo acute toxicity testing of the modified diatomite samples was performed on mice. High adsorbent loading of the selected modified diatomite sample (~250mg/g in 2h) enabled the preparation of comprimates containing adsorbed DS in the amount near to its therapeutic dose. Drug release studies demonstrated prolonged release of DS over a period of 8h from both DAMD comprimates (18% after 8h) and PMDMD comprimates (45% after 8h). The release kinetics for DAMD and PMDMD comprimates fitted well with Korsmeyer-Peppas and Bhaskar models, indicating that the release mechanism was a combination of non-Fickian diffusion and ion exchange process. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Integrity and stability of oral liposomes containing bile salts studied in simulated and ex vivo gastrointestinal media.

    Science.gov (United States)

    Hu, Shunwen; Niu, Mengmeng; Hu, Fuqiang; Lu, Yi; Qi, Jianping; Yin, Zongning; Wu, Wei

    2013-01-30

    The objective of this study was to investigate the integrtity and stability of oral liposomes containing glycocholate (SGC-Lip) in simulated gastrointestinal (GI) media and ex vivo GI media from rats in comparison with conventional liposomes (CH-Lip) composed of soybean phosphatidylcholine and cholesterol. Membrane integrity of liposomes was evaluated by monitoring calcein release, particle size and distribution in different simulated GI media. The stability of liposomes encapsulating insulin was investigated in simulated GI fluids containing pepsin or pancreatin and ex vivo GI enzyme fluids. Simulated GI media with low pH or physiological bile salts resulted in significant increase in calcein release, but dynamic laser scattering data showed that the size and distribution were generally stable. SGC-Lip retained the major amount of the initially encapsulated insulin as compared with CH-Lip in simulated GI fluids (SGF, FaSSGF, SIF and FeSSIF-V2). SGC-Lip retained respectively 17.1% and 20.5% of the initially encapsulated insulin in ex vivo GI fluid, which were also significantly more than CH-Lip. These results suggested that SGC-Lip could protect insulin from degradation to some degree during their transit through the gastrointestinal tract and contributed to enhanced oral absorption. Copyright © 2012 Elsevier B.V. All rights reserved.

  2. Media relations after the introduction of social media

    OpenAIRE

    Mesila, Helin

    2010-01-01

    In the light of the popularity of social media on one hand, and the contradictive relationships between journalists and public relations practitioners on the other hand, the thesis studies media relations after the introduction of social media. The study focuses on media relations in Estonian public relations scenery. The research answers to the questions: - What are media relations today? - What are the functions of social media and media relations in organizational communication? ...

  3. Scaling behavior of microbubbles rising in water-saturated porous media

    Science.gov (United States)

    Kong, X.; Ma, Y.; Scheuermann, A.; Bringemeier, D.; Galindo-Torres, S. A.; Saar, M. O.; Li, L.

    2015-12-01

    Gas transport in the form of discrete microbubbles in saturated porous media is of importance in a number of processes relevant to many geo-environmental and engineering systems such as bubbling of greenhouse gases in river and sea beds, hydrocarbon gas migration in coal cleats and rock fractures, and air sparging for remediation of soil contaminated with volatile organic compounds. Under the assumption of no or minor volume expansion during gravity-driven migration, the transport of a single microbubble can be well described using various drag force models. However, not enough attention has been paid to the collective behavior of microbubbles during their ascend as a plume through the saturated porous medium, involving dynamic interactions between individual bubbles, bubbles and the ambient fluid, as well as bubbles and the solid matrix. With our quasi-2D, lab-scale microbubble migration experiments, where bubbles are continuously released from a diffuser at the bottom of a porous bed of hydrated gel beads, we establish a scaling relationship between the gas (bubble) release rate and various characteristic parameters of the bubble plume, such as plume tip velocity, plume width, and breakthrough time of the plume front. We find that the characteristic width of the bubble plume varies as a power of both the gas release rate and the bed thickness, with exponents of 0.2 and 0.4, respectively. Moreover, the characteristic breakthrough time also scales with both the gas release rate and the bed thickness with power-law exponents of -0.4 and 1.2, respectively. The mean pore-water velocity of the circulating ambient water also follows a power-law relationship with the gas release rate being an exponent of 0.6 of the gas release rate. This can be quantitatively proven using a simplified momentum exchange model together with the above power-law exponents for the bubble plume. These analyses on the experimental results are carried out on the basis of non

  4. Structure of media and communication companies in Ecuador

    Directory of Open Access Journals (Sweden)

    Gabriela Coronel-Salas

    2012-12-01

    Full Text Available The lack of information about the media landscape in Ecuador has prompted the Department of Communication Sciences at the Private Technical University of Loja to map the country's media, production companies, and advertising and public relations agencies. The need for a database on communication issues is still latent in Ecuador. Some public and private agencies have made some contributions to the construction of physical or virtual repositories, but the data provided have been limited to basic, often outdated, contact information. Based on a sample of over one thousand media companies, this study describes their structure, legal and corporate organisation, geographical location, contents, reach, and provided services. This study is an approximation to the country’s media reality and is part of a wider research project entitled “Mapa de la Comunicación de Ecuador” (“Ecuador’s Media Map”.

  5. Can donated media placements reach intended audiences?

    Science.gov (United States)

    Cooper, Crystale Purvis; Gelb, Cynthia A; Chu, Jennifer; Polonec, Lindsey

    2013-09-01

    Donated media placements for public service announcements (PSAs) can be difficult to secure, and may not always reach intended audiences. Strategies used by the Centers for Disease Control and Prevention's (CDC) Screen for Life: National Colorectal Cancer Action Campaign (SFL) to obtain donated media placements include producing a diverse mix of high-quality PSAs, co-branding with state and tribal health agencies, securing celebrity involvement, monitoring media trends to identify new distribution opportunities, and strategically timing the release of PSAs. To investigate open-ended recall of PSAs promoting colorectal cancer screening, CDC conducted 12 focus groups in three U.S. cities with men and women either nearing age 50 years, when screening is recommended to begin, or aged 50-75 years who were not in compliance with screening guidelines. In most focus groups, multiple participants recalled exposure to PSAs promoting colorectal cancer screening, and most of these individuals reported having seen SFL PSAs on television, in transit stations, or on the sides of public buses. Some participants reported exposure to SFL PSAs without prompting from the moderator, as they explained how they learned about the disease. Several participants reported learning key campaign messages from PSAs, including that colorectal cancer screening should begin at age 50 years and screening can find polyps so they can be removed before becoming cancerous. Donated media placements can reach and educate mass audiences, including millions of U.S. adults who have not been screened appropriately for colorectal cancer.

  6. Effect of Human Myotubes-Derived Media on Glucose-Stimulated Insulin Secretion

    Directory of Open Access Journals (Sweden)

    Maria L. Mizgier

    2017-01-01

    Full Text Available Fasting to postprandial transition requires a tight adjustment of insulin secretion to its demand, so tissue (e.g., skeletal muscle glucose supply is assured while hypo-/hyperglycemia are prevented. High muscle glucose disposal after meals is pivotal for adapting to increased glycemia and might drive insulin secretion through muscle-released factors (e.g., myokines. We hypothesized that insulin influences myokine secretion and then increases glucose-stimulated insulin secretion (GSIS. In conditioned media from human myotubes incubated with/without insulin (100 nmol/L for 24 h, myokines were qualitatively and quantitatively characterized using an antibody-based array and ELISA-based technology, respectively. C57BL6/J mice islets and Wistar rat beta cells were incubated for 24 h with control and conditioned media from noninsulin- and insulin-treated myotubes prior to GSIS determination. Conditioned media from insulin-treated versus nontreated myotubes had higher RANTES but lower IL6, IL8, and MCP1 concentration. Qualitative analyses revealed that conditioned media from noninsulin- and insulin-treated myotubes expressed 32 and 23 out of 80 myokines, respectively. Islets incubated with conditioned media from noninsulin-treated myotubes had higher GSIS versus control islets (p<0.05. Meanwhile, conditioned media from insulin-treated myotubes did not influence GSIS. In beta cells, GSIS was similar across conditions. In conclusion, factors being present in noninsulin-stimulated muscle cell-derived media appear to influence GSIS in mice islets.

  7. Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in GABAergic neurons: vesicular versus non-vesicular release of GABA

    DEFF Research Database (Denmark)

    Belhage, B; Hansen, Gert Helge; Schousboe, A

    1993-01-01

    differences in the mode of action of the two depolarizing stimuli were reflected in the properties of the increase in [Ca++]i elicited by 55 mM K+ and 100 microM glutamate, respectively. The K(+)-induced increase in [Ca++]i was reduced by both verapamil and Ca(++)-free media whereas the corresponding...... neurotransmitter glutamate (100 microM). Both depolarizing stimuli exerted prompt increases in the release of preloaded [3H]GABA as well as in [Ca++]i. However, the basic properties of transmitter release and the increase in [Ca++]i under a variety of conditions were different during stimulation with K...... was also reduced by organic (verapamil) and inorganic (Co++) Ca++ channel blockers but was insensitive to the GABA transport inhibitor SKF 89976A. In contrast, the second phase was less sensitive to nocodazole and Ca++ channel antagonists but could be inhibited by SKF 89976A. The glutamate-induced [3H...

  8. Ultrasound Enhanced Matrix Metalloproteinase-9 Triggered Release of Contents from Echogenic Liposomes

    Science.gov (United States)

    Nahire, Rahul; Paul, Shirshendu; Scott, Michael D.; Singh, Raushan K.; Muhonen, Wallace W.; Shabb, John; Gange, Kara N.; Srivastava, D. K.; Sarkar, Kausik; Mallik, Sanku

    2012-01-01

    The extracellular enzyme matrix metalloproteinase-9 (MMP-9) is overexpressed in atherosclerotic plaques and in metastatic cancers. The enzyme is responsible for rupture of the plaques and for the invasion and metastasis of a large number of cancers. The ability of ultrasonic excitation to induce thermal and mechanical effects has been used to release drugs from different carriers. However, majority of these studies were performed with low frequency ultrasound (LFUS) at kHz frequencies. Clinical usage of LFUS excitations will be limited due to harmful biological effects. Herein, we report our results on the release of encapsulated contents from substrate lipopeptide incorporated echogenic liposomes triggered by recombinant human MMP-9. The contents release was further enhanced by the application of diagnostic frequency (3 MHz) ultrasound. The echogenic liposomes were successfully imaged employing a medical ultrasound transducer (4 – 15 MHz). The conditioned cell culture media from cancer cells (secreting MMP-9) released the encapsulated dye from the liposomes (30 – 50%) and this release is also increased (50 – 80%) by applying diagnostic frequency ultrasound (3 MHz) for 3 minutes. With further developments, these liposomes have the potential to serve as multimodal carriers for triggered release and simultaneous ultrasound imaging. PMID:22849291

  9. Some features of South-Ukrainian NPP information centre's interaction with mass media in post Chernobyl period

    International Nuclear Information System (INIS)

    Kiyashko, S.; Kurilchik, N.

    1995-01-01

    Using the above methods of interaction with the off-site media helped the South Ukraine NPP information centre achieve meaningful results in restoring the image of nuclear power ad making it more trustworthy. This is supported by a review of media Publications since 1989. Quantitative and qualitative modifications of the information flow to the media have yielded substantial changes of the structure of news releases about the South Ukraine NPP and nuclear power. Background information has increased from 1. 5 to 50 percent. Negative information is no longer dominating, and the Chernobyl topic is counterbalanced with diverse NucNet materials about nuclear from throughout the world. (author)

  10. Environmental radiological surveillance in perspective: the relative importance of environmental media as a function of effluent pathway and radionuclides

    International Nuclear Information System (INIS)

    Denham, D.H.

    1977-01-01

    Most published guidelines for environmental surveillance emphasize the collection and analysis of specific media (e.g. air, water, milk, direct radiation) without total regard for the potential dose impact of the radionuclides expected in or actually present in the effluent streams FR-om nuclear facilities. To determine the relative importance of medium/nuclide combinations in environmental surveillance, the experience at major ERDA sites and at operating nuclear power plants was reviewed. Typical release rates for nuclide groupings (tritium, noble gases, radioiodine, mixed fission or activation products, and transuranics) in those effluent streams were followed through various environmental pathways. By using this scheme the environmental medium which is most prominent in the critical dose pathway to man was determined. It was also possible to determine points of short-or long-term contaminant accumulation. Following these combination providing the relative importance of sampling specific environmental media with emphasis on the radiation dose to a critical population group. Finally, the results of these environmental pathway studies are presented in tabular form to provide ready reference for environmental surveillance program design or evaluation

  11. Final voluntary release assessment/corrective action report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-12

    The US Department of Energy, Carlsbad Area Office (DOE-CAO) has completed a voluntary release assessment sampling program at selected Solid Waste Management Units (SWMUs) at the Waste Isolation Pilot Plant (WIPP). This Voluntary Release Assessment/Corrective Action (RA/CA) report has been prepared for final submittal to the Environmental protection Agency (EPA) Region 6, Hazardous Waste Management Division and the New Mexico Environment Department (NMED) Hazardous and Radioactive Materials Bureau to describe the results of voluntary release assessment sampling and proposed corrective actions at the SWMU sites. The Voluntary RA/CA Program is intended to be the first phase in implementing the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) and corrective action process at the WIPP. Data generated as part of this sampling program are intended to update the RCRA Facility Assessment (RFA) for the WIPP (Assessment of Solid Waste Management Units at the Waste Isolation Pilot Plant), NMED/DOE/AIP 94/1. This Final Voluntary RA/CA Report documents the results of release assessment sampling at 11 SWMUs identified in the RFA. With this submittal, DOE formally requests a No Further Action determination for these SWMUs. Additionally, this report provides information to support DOE`s request for No Further Action at the Brinderson and Construction landfill SWMUs, and to support DOE`s request for approval of proposed corrective actions at three other SWMUs (the Badger Unit Drill Pad, the Cotton Baby Drill Pad, and the DOE-1 Drill Pad). This information is provided to document the results of the Voluntary RA/CA activities submitted to the EPA and NMED in August 1995.

  12. The Influence of Media Violence on Youth.

    Science.gov (United States)

    Anderson, Craig A; Berkowitz, Leonard; Donnerstein, Edward; Huesmann, L Rowell; Johnson, James D; Linz, Daniel; Malamuth, Neil M; Wartella, Ellen

    2003-12-01

    Research on violent television and films, video games, and music reveals unequivocal evidence that media violence increases the likelihood of aggressive and violent behavior in both immediate and long-term contexts. The effects appear larger for milder than for more severe forms of aggression, but the effects on severe forms of violence are also substantial (r = .13 to .32) when compared with effects of other violence risk factors or medical effects deemed important by the medical community (e.g., effect of aspirin on heart attacks). The research base is large; diverse in methods, samples, and media genres; and consistent in overall findings. The evidence is clearest within the most extensively researched domain, television and film violence. The growing body of video-game research yields essentially the same conclusions. Short-term exposure increases the likelihood of physically and verbally aggressive behavior, aggressive thoughts, and aggressive emotions. Recent large-scale longitudinal studies provide converging evidence linking frequent exposure to violent media in childhood with aggression later in life, including physical assaults and spouse abuse. Because extremely violent criminal behaviors (e.g., forcible rape, aggravated assault, homicide) are rare, new longitudinal studies with larger samples are needed to estimate accurately how much habitual childhood exposure to media violence increases the risk for extreme violence. Well-supported theory delineates why and when exposure to media violence increases aggression and violence. Media violence produces short-term increases by priming existing aggressive scripts and cognitions, increasing physiological arousal, and triggering an automatic tendency to imitate observed behaviors. Media violence produces long-term effects via several types of learning processes leading to the acquisition of lasting (and automatically accessible) aggressive scripts, interpretational schemas, and aggression-supporting beliefs

  13. An Investigation on Metallic Ion Release from Four Dental Casting Alloys

    Directory of Open Access Journals (Sweden)

    F. Nejatidanesh

    2005-12-01

    Full Text Available Statement of Problem: Element release from dental casting alloys into the oral environment is of clinical concern and is considered to be a potential health problem to all patients.Purpose: The aim of this study was to investigate the metallic ion release of four base metal alloys.Materials and Methods: Two Ni-Cr (Minalux and Supercast and two Co-Cr alloys (Minalia and Wironit were examined. Nine specimens of each type were prepared in 13×11×1.4 mm dimensions and each of the four alloys (3 specimens per group were conditioned in artificial saliva at 37 c for one, three and seven days.The conditioning media were analyzed for element-release using Inductive CoupledPlasma Atomic Emission Spectrophotometer (ICPAES. Collected data were statistically analyzed using ANOVA and Duncan multiple range test (P< 0.05.Results: The greatest amount of element release was seen after seven days (134.9 ppb Supercast, 159.2 ppb Minalux, 197.2 ppb Minalia, and 230.2 ppb Wironit. There was a significant difference between the released elements from the alloys after the three conditioning times (p<0.001.Conclusion: Element release from the studied alloys is proportional to the conditioning time. The Ni-Cr alloys tested in this investigation were more resistant to corrosion as compared to the Co-Cr alloys in artificial saliva. Supercast had the highest corrosion resistance.

  14. Swelling kinetics of spray-dried chitosan acetate assessed by magnetic resonance imaging and their relation to drug release kinetics of chitosan matrix tablets.

    Science.gov (United States)

    Huanbutta, Kampanart; Sriamornsak, Pornsak; Limmatvapirat, Sontaya; Luangtana-anan, Manee; Yoshihashi, Yasuo; Yonemochi, Etsuo; Terada, Katsuhide; Nunthanid, Jurairat

    2011-02-01

    Magnetic resonance imaging (MRI) was used to assess in situ swelling behaviors of spray-dried chitosan acetate (CSA) in 0.1N HCl, pH 6.8 and pH 5.0 Tris-HCl buffers. The in vitro drug releases from CSA matrix tablets containing the model drugs, diclofenac sodium and theophylline were investigated in all media using USP-4 apparatus. The effect of chitosan molecular weight, especially in pH 6.8 Tris-HCl, was also studied. In 0.1N HCl, the drug release from the matrix tablets was the lowest in relation to the highest swelling of CSA. The swelling kinetics in Tris-HCl buffers are Fickian diffusion according to their best fit to Higuchi's model as well as the drug release kinetics in all the media. The high swelling rate (k(s)(')) was found to delay the drug release rate (k'). The linear relationship between the swelling and fractions of drug release in Tris-HCl buffers was observed, indicating an important role of the swelling on controlling the drug release mechanism. Additionally, CSA of 200 and 800 kDa chitosan did not swell in pH 6.8 Tris-HCl but disintegrated into fractions, and the drug release from the matrix tablets was the highest. Copyright © 2010 Elsevier B.V. All rights reserved.

  15. Media Coverage of Nuclear Energy after Fukushima

    International Nuclear Information System (INIS)

    Oltra, C.; Roman, P.; Prades, A.

    2013-01-01

    This report presents the main findings of a content analysis of printed media coverage of nuclear energy in Spain before and after the Fukushima accident. Our main objective is to understand the changes in the presentation of nuclear fission and nuclear fusion as a result of the accident in Japan. We specifically analyze the volume of coverage and thematic content in the media coverage for nuclear fusion from a sample of Spanish print articles in more than 20 newspapers from 2008 to 2012. We also analyze the media coverage of nuclear energy (fission) in three main Spanish newspapers one year before and one year after the accident. The results illustrate how the media contributed to the presentation of nuclear power in the months before and after the accident. This could have implications for the public understanding of nuclear power. (Author)

  16. Media Coverage of Nuclear Energy after Fukushima

    Energy Technology Data Exchange (ETDEWEB)

    Oltra, C.; Roman, P.; Prades, A.

    2013-07-01

    This report presents the main findings of a content analysis of printed media coverage of nuclear energy in Spain before and after the Fukushima accident. Our main objective is to understand the changes in the presentation of nuclear fission and nuclear fusion as a result of the accident in Japan. We specifically analyze the volume of coverage and thematic content in the media coverage for nuclear fusion from a sample of Spanish print articles in more than 20 newspapers from 2008 to 2012. We also analyze the media coverage of nuclear energy (fission) in three main Spanish newspapers one year before and one year after the accident. The results illustrate how the media contributed to the presentation of nuclear power in the months before and after the accident. This could have implications for the public understanding of nuclear power. (Author)

  17. Determining Effect of Digital And Media Activities On Media And Science Literacy Of Middle-School Students And Parents

    Directory of Open Access Journals (Sweden)

    Bilge CAN

    2018-01-01

    Full Text Available This research aims determining effect of digital and media activities on media and science literacy of middle-school students and parents and identifying the relationship between them. Quasi- experimental model has been used by which pretest-posttest studies have been held on one group by using quantitative data during research. The sample of the research consists of 60 students and 119 parents who attend a school in the province of Bursa in the academic year of 2013-2014. According to data analysis obtained in the research, there is a significant relation between pretests and posttests about scientific literacy of middle-school students and parents relating to Digital and Media Activities. There is a relation between media and scientific literacy of students and mothers as parents. There is a difference between the applied PISA and TIMSS exams and the students' science literacy. In the light of these results, some suggestion has been offered with regard to focusing on the importance of 21st century skills and literacy, developing scientific and media literacy level and obtaining more comprehensive results.

  18. Ultrasound stimulated release of gallic acid from chitin hydrogel matrix

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Huixin; Kobayashi, Takaomi, E-mail: takaomi@nagaokaut.ac.jp

    2017-06-01

    Ultrasound (US) stimulated drug release was examined in this study using a chitin hydrogel matrix loaded with gallic acid (GA), a drug used for wound healing and anticancer. Using phase inversion, GA-chitin hydrogels were prepared from chitin-dimethylacetamide (DMAc)/lithium chloride (LiCl) solution in the presence of GA, with 24 h exposure of the solution to water vapor. The GA release from the GA-chitin hydrogel was examined under different US powers of 0–30 W at 43 kHz. The effects of GA loading amounts in the hydrogels (0.54, 0.43, and 0.25 mg/cm{sup 3}) and chitin concentrations (0.1, 0.5, and 1 wt%) on the release behaviors were recorded under 43 kHz US exposure at 30 W. Results show that US accelerated the release efficiencies for all samples. Furthermore, the release efficiency increased concomitantly with increasing US power, GA loading amount, and decrease of the chitin concentration. The highest release rate of 0.74 μg/mL·min was obtained from 0.54 mg/cm{sup 3} of GA-loaded hydrogel fabricated from a 0.1 wt% chitin mixture solution under 43 kHz US exposure at 30 W: nine times higher than that of the sample without US exposure. The hydrogel viscoelasticity demonstrated that the US irradiation rigidified the material. FT-IR showed that US can break the hydrogen bonds in the GA-chitin hydrogels. - Highlights: • Ultrasound (US) stimulated Gallic acid (GA) release from chitin hydrogel was studied. • The release efficiency of GA from chitin hydrogel increased nine times when irradiated by 43 kHz US compared with the sample without US. • Generalized 2D correlation and deconvolution study of FT-IR showed that US could promote the GA release by breaking hydrogen bonds.

  19. Ultrasound stimulated release of gallic acid from chitin hydrogel matrix

    International Nuclear Information System (INIS)

    Jiang, Huixin; Kobayashi, Takaomi

    2017-01-01

    Ultrasound (US) stimulated drug release was examined in this study using a chitin hydrogel matrix loaded with gallic acid (GA), a drug used for wound healing and anticancer. Using phase inversion, GA-chitin hydrogels were prepared from chitin-dimethylacetamide (DMAc)/lithium chloride (LiCl) solution in the presence of GA, with 24 h exposure of the solution to water vapor. The GA release from the GA-chitin hydrogel was examined under different US powers of 0–30 W at 43 kHz. The effects of GA loading amounts in the hydrogels (0.54, 0.43, and 0.25 mg/cm 3 ) and chitin concentrations (0.1, 0.5, and 1 wt%) on the release behaviors were recorded under 43 kHz US exposure at 30 W. Results show that US accelerated the release efficiencies for all samples. Furthermore, the release efficiency increased concomitantly with increasing US power, GA loading amount, and decrease of the chitin concentration. The highest release rate of 0.74 μg/mL·min was obtained from 0.54 mg/cm 3 of GA-loaded hydrogel fabricated from a 0.1 wt% chitin mixture solution under 43 kHz US exposure at 30 W: nine times higher than that of the sample without US exposure. The hydrogel viscoelasticity demonstrated that the US irradiation rigidified the material. FT-IR showed that US can break the hydrogen bonds in the GA-chitin hydrogels. - Highlights: • Ultrasound (US) stimulated Gallic acid (GA) release from chitin hydrogel was studied. • The release efficiency of GA from chitin hydrogel increased nine times when irradiated by 43 kHz US compared with the sample without US. • Generalized 2D correlation and deconvolution study of FT-IR showed that US could promote the GA release by breaking hydrogen bonds.

  20. Measuring New Media Literacies: Towards the Development of a Comprehensive Assessment Tool

    Science.gov (United States)

    Literat, Ioana

    2014-01-01

    This study assesses the psychometric properties of a newly tested self-report assessment tool for media literacy, based on the twelve new media literacy skills (NMLs) developed by Jenkins et al. (2006). The sample (N = 327) consisted of normal volunteers who completed a comprehensive online survey that measured their NML skills, media exposure,…

  1. Release of fission products in transients

    International Nuclear Information System (INIS)

    Christensen, H.; Lundqwist, R.

    1979-07-01

    A station for automatic sampling of coolant has been put in operation at the Oskarshamn-1 reactor. The release of 131 J and other fission products in spikes in connection with reactor trips and scheduled shutdowns has been measured. A model developed at General Electric has been used to predict the spike release in Oskarshamn-1 and the predicted values have been compared with experimental values. Literature data of iodine spikes in BWR and PWR have been reviewed. (author)

  2. Release of engineered nanomaterials from polymer nanocomposites: the effect of matrix degradation.

    Science.gov (United States)

    Duncan, Timothy V

    2015-01-14

    Polymer nanocomposites-polymer-based materials that incorporate filler elements possessing at least one dimension in the nanometer range-are increasingly being developed for commercial applications ranging from building infrastructure to food packaging to biomedical devices and implants. Despite a wide range of intended applications, it is also important to understand the potential for exposure to these nanofillers, which could be released during routine use or abuse of these materials so that it can be determined whether they pose a risk to human health or the environment. This article is the second of a pair that review what is known about the release of engineered nanomaterials (ENMs) from polymer nanocomposites. Two roughly separate ENM release paradigms are considered in this series: the release of ENMs via passive diffusion, desorption, and dissolution into external liquid media and the release of ENMs assisted by matrix degradation. The present article is focused primarily on the second paradigm and includes a thorough, critical review of the associated body of peer-reviewed literature on ENM release by matrix degradation mechanisms, including photodegradation, thermal decomposition, mechanical wear, and hydrolysis. These release mechanisms may be especially relevant to nanocomposites that are likely to be subjected to weathering, including construction and infrastructural materials, sporting equipment, and materials that might potentially end up in landfills. This review pays particular attention to studies that shed light on specific release mechanisms and synergistic mechanistic relationships. The review concludes with a short section on knowledge gaps and future research needs.

  3. A Perspective on Media Entrepreneurship Policy

    DEFF Research Database (Denmark)

    Khajeheian, Datis

    2014-01-01

    and practice. To fill the gap, media entrepreneurship is considered as a practical approach to implement the acquired knowledge to create new products and services, even via imitative innovations and cloning successful business models. Data, which was gathered from samples of the Iranian entrepreneurs brought......, particularly in digital media industry because of its particular potential in value creation. Also, literature about modes of innovation and the way nations benefit from their resources, along with various types of capital, considered for provision of a contingent approach. By developing the model from...

  4. Media Use by Children, and Parents' Views on Children's Media Usage.

    Science.gov (United States)

    Dinleyici, Meltem; Carman, Kursat Bora; Ozturk, Emel; Sahin-Dagli, Figen

    2016-06-07

    New (mobile phones, smartphones, tablets, and social media) and traditional media (television) have come to dominate the lives of many children and adolescents. Despite all of this media time and new technology, many parents seem to have few rules regarding the use of media by their children and adolescents. The aim of this study was to evaluate media access/use of children and to evaluate beliefs and attitudes of parents concerning the use of old and new media in Turkey. This is a cross-sectional electronic survey of a national convenience sample in Turkey via SurveyMonkey, including 41 questions regarding topics relevant to television, computers, mobile phones, iPad/tablet use, and social media accounts. The responses of the 333 participants (238 women, 95 men; 27-63 years) were evaluated. The average daily watching alone time was 0 to 2 hours among 53.4% (46/86), and daily coviewing time with parents of children was 0 to 2 hours among 62.7% (54/86) of children below 2 years of age. Regarding parents' monitoring their children's computer use (n=178), 35.4% (63/178) of the parents prefer coviewing, 13.5% of the parents use a family filter (24/178), and 33.1% (59/178) of the parents prefer to check Web history. Approximately 71.2% (237/333) of the participants had an iPad/tablet in the house, 84.3% (200/333) of the parents give their children permission to use the iPad/tablet. Of the parents, 22.5% (45/200) noted that their children used the iPad/tablet at the table during lunch/dinner and 57.9% (26/45) of these children were aged 5 years and below. Of parents, 27.3% (91/333) agreed that the optimal age for owning a mobile phone was 12 years, and 18.0% (60/333) of the parents noted that their children (one-third was below 2 years) used the mobile phone at the table during meals. A total of 33.3% (111/333) children/adolescents have a Facebook profile, and 54.0% (60/111) were below 13 years of age. Approximately 89.2% (297/333) of the parents emphasized that the

  5. HUBUNGAN PENGGUNAAN JENIS MEDIA MASSA DENGAN KEJADIAN DATING VIOLENCE

    Directory of Open Access Journals (Sweden)

    Yekti Satriyandari

    2017-03-01

    Full Text Available Abstrack: The study aimed to determine the correlation between the use of mass media and dating violence occurrence at State Senior High School 1 Pajangan Bantul Yogyakarta. The correlation study used cross sectional approach. Samples were 108 students (total sampling. The measuring instruments were checklists and questionnaires. The data were analyzed using Chi Square. That was indicated by the value x 2 (12.531 with the significant value (p = 0.002 <0.05, and the contingency coefficient (0,322. There was a correlation between the use of mass media and dating violence occurrence at State Senior High School 1 Pajangan Bantul Yogyakarta. It is expected that teenagers do not date in order to avoid the incidence of dating violence and are able to use information technology properly and appropriately.Keywords: the use of mass media, dating violence

  6. Recording performances in perpendicular magnetic patterned media

    International Nuclear Information System (INIS)

    Asbahi, M; Moritz, J; Dieny, B; Gourgon, C; Perret, C; Van de Veerdonk, R J M

    2010-01-01

    We report on the recording performances and signal-to-noise ratio (SNR) analyses of perpendicular magnetic bit-patterned media. Two different types of magnetic samples are investigated. They differ by the way that they were patterned (nano-imprint versus e-beam lithography) as well as their magnetic properties (Co/Pt multilayers and CoCrPt alloy are the recording layers).Using a contact read/write quasi-static tester, we were able to characterize the write windows, the bit error rates and measure the SNR. The influence of magnetic properties and media microstructure on the writing processes is studied. We show also that the lithographical method used to replicate the media induces more or less noise due to structural distributions.

  7. 14C release from failed spent fuel containers

    International Nuclear Information System (INIS)

    Pescatore, C.

    1990-01-01

    Partially failed containers may provide a meaningful barrier to the release of gaseous radionuclides. A modeling approach is outlined and sample calculations are provided that show the effects on release due to a limited perforation area, to decreasing temperature, and to the partial occlusion of the perforated area by corrosion products. 8 refs., 2 tabs

  8. BUKU GIZI BRAILLE SEBAGAI MEDIA PENDIDIKAN UNTUK MENINGKATKAN PENGETAHUAN ANAK TUNANETRA

    Directory of Open Access Journals (Sweden)

    Resa Wahyuni

    2016-01-01

    Full Text Available Anak tunanetra memiliki resiko yang sama seperti anak normal untuk mengalami masalah gizi karena kurangnya pengetahuan gizi, sehingga diperlukan pendidikan gizi beserta media tepat untuk dapat meningkatkan pengetahuan gizi anak-anak  tunanetra. Penelitian ini bertujuan untuk mengetahui apakah terdapat perbedaan signifikan antara pengetahuan gizi buah dan sayur sebelum diberi dan setelah diberi media buku gizi braille pada anak tunanetra di Madrasah Ibtidaiyah Luar Biasa (MILB Budi Asih Semarang. Jenis penelitian yang digunakan adalah pra eksperimen dengan pendekatan one group pretest posttest design. Pengambilan sampel pada penelitian ini dilakukan dengan total sampling karena jumlah populasi yang terbatas, yaitu sebanyak 7 sampel. Diperoleh rata-rata skor untuk pre test sebesar 10,57, dan rata-rata skor post test sebesar 16,71. Berdasarkan uji t test berpasangan yang telah dilakukan, diperoleh nilai sig (0,018 < 0,05 hal ini berati terdapat perbedaan yang signifikan antara skor sebelum diberi media buku gizi braille dan setelah diberi media buku gizi braille. Children with visual impairment have the same risk as eyesight children to have a nutrition problems because the lack of nutrition knowledge, in order to the nutrition education is required with the appropriate media to be able to improve theirs nutrition knowledge. This study aimed to know the significant different about nutrient of fruits and vegetables knowledge before and after given nutrient book in children with visual impairment at Madrasah Ibtidaiyah Luar Biasa (MILB Budi Asih Semarang. The type of this research was pre experiment with one group pretest posttest design approach. Sampling was used total sampling because the population was limited, there were 7 samples. The mean of pre test score was 10,57 dan post score was 16,71. Based on the paired t test, the value of sig (0,018 <0,05 it means there were significant differences between score before given nutrient media braille

  9. Communal farming, climate change adaptation and the media in Zimbabwe

    Directory of Open Access Journals (Sweden)

    Mthokozisi P. Ndhlovu

    2016-03-01

    Full Text Available Climate change is destroying Zimbabwean communal farmers’ agricultural activities – a source of living for most people. As communal farmers struggle to adapt, the media is expected to assume a fundamental theoretical role of educating and informing them about the appropriate adaptation techniques. Located in Umguza District in Matabeleland North Province, the study explored how communal farmers created meaning out of climate change media content and its influence on their agricultural practices from October 2014 to April 2015. In doing so, the study used the Two-Step Flow theory and Hall’s Encoding and Decoding Model. Entrenched in pragmatism, the study embedded quantitative techniques at different stages. Multistage sampling combining Simple Random Sampling (SRS, purposive and systematic sampling techniques was used to identify the 263 households for semi structured questionnaires, direct observations and in-depth interviews. The findings were analysed using Statistical Package for the Social Sciences (SPSS, thematic analysis and pattern matching. The results show that personal observations; print, broadcast and online media; and opinion leaders were the main sources of climate change information. The radio was the most used medium in communicating climate change adaptation though it was the second most accessed after mobile phones. Conservation Agriculture and planting of drought-resistant crops were some of the adaptation techniques communicated in the media. When interacting with media content, communal farmers create their own meaning influenced by their cultural values, resulting in some adopting, rejecting or modifying certain adaptation techniques. The study concludes that opinion leaders are fundamental in communal farmers’ interaction with media but their influence must not be overestimated.

  10. Media education and media influence on youth

    OpenAIRE

    LILÁK, Karel

    2011-01-01

    Bachelor´s work is focused on the questions of the medial education and the medias themselves. This work also investigate with the influence of the action of medias to the students of apprenticeship. The first part of the theoretical work has generally explains what is media education, what is its significance for society and for the benefit of education in school. They are given functions, types and objectives of media education and communications capabilities via the media. The second part ...

  11. Mechanisms of iodine release from iodoapatite in aqueous solution

    Science.gov (United States)

    Zhang, Z.; Wang, J.

    2017-12-01

    Immobilization of iodine-129 with waste forms in geological setting is challenging due to its extremely long half-life and high volatility in the environment. To evaluate the long-term performance of waste form, it is imperative to determine the release mechanism of iodine hosted in the waste form materials. This study investigated the iodine released from apatite structured waste form Pb9.85 (VO4)6 I1.7 to understand how diffusion and dissolution control the durability of apatite waste form. A standard semi-dynamic leach test was adopted in this study. Samples were exposed in fresh leachant periodically and the leachant was replaced after each interval. Each experiment was carried out in cap-sealed Teflon vessels under constant temperature (e.g. 90 °C). ICP-MS analysis on the reacted leachates shows that Pb and V were released constantly and congruently with the stoichiometric ratio of Pb/V. However, iodine release is incongruent and time dependent. The iodine release rate starts significantly higher than the corresponding stoichiometric value and gradually decreases, approaching the stoichiometric value. Therefore, a dual-mode mechanism is proposed to account for the iodine release from apatite, which is dominated by short-term diffusion and long-term dissolution processes. Additional tests show that the element release rates depend on a number of test parameters, including sample surface to solution volume ratio (m-1), interval (day), temperature (°C), and solution pH. This study provides a quantitative characterization of iodine release mechanism. The activation energy of iodine leaching 21±1.6 kJ/mol was obtained by varying the test temperature. At the test conditions of to neutral pH and 90 °C, the long-term iodine release rate 3.3 mg/(m2 • day) is projected by normalizing sample surface area to solution volume ratio (S/V) to 1.0 m-1 and interval to 1 day. These findings demonstrate i) the feasibility of our approach to quantify the release mechanism

  12. Photographed by the Earth: War and media in light of nuclear events

    Directory of Open Access Journals (Sweden)

    Thomas Pringle

    2014-12-01

    Full Text Available This article charts a media historical relation between radiation and celluloid film, ranging from the downwind 1956 production of The Conqueror to early scientific imaging practices, war photography, war documentaries, military industrial film, and contemporary artists working on radiation aesthetics. Posing the collection as a diagnostic media ecology, this article argues that the valuable evidence provided by the environmental metadata stored in celluloid film is the product of ecological warfare and violence. By turning to the material sciences for a better understanding of how nuclear weapons affect media on large spatial and temporal scales we gain a parallax view to how photographic practices – defined as the aesthetic exchange of light and energy – occur autonomously within our ecology, although some of these forces are mobilised in deadly and imperceptible ways. By demonstrating that non-human agencies released by Cold War energy policies have contaminated military industrial and commercial film archives alike, this article asserts that nuclear testing and warfare have contributed to a global condition of test-subjectivity that can be evidenced by diagnostic media ecology.

  13. Social Media Use and Conduct Problems in Emerging Adults.

    Science.gov (United States)

    Galica, Victoria L; Vannucci, Anna; Flannery, Kaitlin M; Ohannessian, Christine McCauley

    2017-07-01

    Social media use has become pervasive in the lives of emerging adults. Although social media may provide individuals with positive opportunities for communication and learning, social media sites also may provide an outlet for youth conduct problems, such as bullying, harassment, and intentional hostility and aggression toward others. Yet, the relationship between social media use and conduct problems remains unclear. This study investigated the association between conduct disorder (CD) symptoms before age 15 and social media use during emerging adulthood in a large, nationally representative sample. Concurrent associations between antisocial personality disorder (ASPD) symptoms and social media use in emerging adults also were examined. Data for this study were based on 567 emerging adults (50.2 percent female; M age  = 20.0 years). Self-report questionnaires were completed online. Results suggested that more childhood CD symptoms were significantly associated with greater daily social media use during emerging adulthood, and that more daily social media use was significantly associated with current ASPD symptoms. Possible directional and cyclical explanations for these findings are explored. Given the pervasiveness of social media in the lives of emerging adults, these results underscore the importance of considering nuanced methods for using social media sites to encourage positive social interactions and to displace the promotion of conduct problems.

  14. Radionuclide releases from natural analogues of spent nuclear fuel

    International Nuclear Information System (INIS)

    Curtis, D.B.; Fabryka-Martin, J.; Dixon, P.; Aguilar, R.; Rokop, D.; Cramer, J.

    1993-01-01

    Measures of 99 Tc, 129 I, 239 Pu and U concentrations in rock samples from uranium deposits at Cigar Lake and Koongarra have been used to study processes of radionuclide release from uranium minerals. Rates of release have been immeasurably slow at Cigar Lake. At Koongarra release rates appear to have been faster, producing small deficiencies of 99 Tc, and larger ones of 129 I. The inferred differences in radionuclide release rates are consistent with expected differences in uranium mineral degradation rates produced by the differing hydrogeochemical environments at the two sites

  15. Offices Press as the Main Source Documentary of the Media. Fuenlabrada as Case Study

    Directory of Open Access Journals (Sweden)

    Beatriz Catalina García

    2015-07-01

    Full Text Available The routines documentaries of professionals working in the press offices of any public or private entity have changed extraordinarily with adaptation of the tools available on the Internet. These alterations have dramatically impacted the provision of information to various media: the generated files in the cabinet, mostly press releases, are submitted in online format. In this article are analyze the relation among local media and press office of the City of Fuenlabrada. Through monitoring and content analysis of the news published in local media, this paper therefore seeks to ascertain the acceptance or rejection of the information generated by this institution and proposals for publication in different media. As a complementary purpose and by means of a structured questionnaire, are analyzed the relations between local journalists and the press office professionals. Among the most important findings, is observed a clear trend to consider the city hall as their main source of information with a remarkable adoption of institutional information on the content of the different media.

  16. Amidase-responsive controlled release of antitumoral drug into intracellular media using gluconamide-capped mesoporous silica nanoparticles

    Science.gov (United States)

    Candel, Inmaculada; Aznar, Elena; Mondragón, Laura; Torre, Cristina De La; Martínez-Máñez, Ramón; Sancenón, Félix; Marcos, M. Dolores; Amorós, Pedro; Guillem, Carmen; Pérez-Payá, Enrique; Costero, Ana; Gil, Salvador; Parra, Margarita

    2012-10-01

    MCM-41 silica nanoparticles were used as inorganic scaffolding to prepare a nanoscopic-capped hybrid material S1, which was able to release an entrapped cargo in the presence of certain enzymes, whereas in the absence of enzymes, a zero release system was obtained. S1 was prepared by loading nanoparticles with Safranine O dye and was then capped with a gluconamide derivative. In the absence of enzymes, the release of the dye from the aqueous suspensions of S1 was inhibited as a result of the steric hindrance imposed by the bulky gluconamide derivative, the polymerized gluconamide layer and the formation of a dense hydrogen-bonded network around the pore outlets. Upon the addition of amidase and pronase enzymes, delivery of Safranine O dye was observed due to the enzymatic hydrolysis of the amide bond in the anchored gluconamide derivative. S1 nanoparticles were not toxic for cells, as demonstrated by cell viability assays using HeLa and MCF-7 cell lines, and were associated with lysosomes, as shown by confocal microscopy. Finally, the S1-CPT material loaded with the cytotoxic drug camptothecin and capped with the gluconamide derivative was prepared. The HeLa cells treated with S1-CPT underwent cell death as a result of material internalization, and of the subsequent cellular enzyme-mediated hydrolysis and aperture of the molecular gate, which induced the release of the camptothecin cargo.

  17. Information sources in the Spanish social media during the “Three Days of March” (11-13 March 2004

    Directory of Open Access Journals (Sweden)

    Dra. Mª Montserrat Doval-Avendaño

    2010-01-01

    Full Text Available This research tries to establish whether the Spanish public agenda during the period from 11 to 13 March, 2004, was set by the social media or the traditional media. Based on the content analysis of traditional media, such as CadenaSer, El Mundo and El País, and social media (mainly blogs and forums it was concluded that the agenda of the social media, at a cognitive level, was actually established by the traditional media. It was also established that, during those three days, the social media worked as collectors of information from Spanish and foreign traditional media; as compilers of press releases from social organizations calling for demonstrations; and as diffusers of opinions linking the terrorist attack to the foreign policy of the Aznar Government, and of opinions that asked people to respond to terrorism through the polls. The agenda-setting, therefore, continued to be in the hands of the traditional media, not only at the basic level of the agenda -transfer of salience from the media to the public agenda-, but also at the attribute level -transfer of the specific attributes- and framing of the terrorist attacks.

  18. Prostaglandin release from in vitro guinea-pig gallbladder.

    Science.gov (United States)

    Booker, M L; LaMorte, W W

    1983-02-01

    In order to study prostaglandin release from guinea pig gallbladder, full thickness tissue sections were incubated for one hour in Krebs solution. Extraction and two dimensional chromatography of incubation media obtained in the presence of radio-labelled arachidonic acid demonstrated the presence of PGE2, PGF2 alpha, 6-keto-PGF1 alpha and thromboxane B2. These results were supported by radioimmunoassay of incubations conducted in the absence of exogenous arachidonate and in the presence of varying concentrations of unlabelled exogenous arachidonate. The previously reported predominance of PGE2 was only seen at high concentrations of exogenous arachidonate.

  19. 14C release from failed spent fuel containers

    International Nuclear Information System (INIS)

    Pescatore, C.

    1989-01-01

    Partially failed containers may provide a meaningful barrier to the release of gaseous 14 CO 2 . A modeling approach is outlined and sample calculations are provided that show the effect on release due to a limited perforation area, to decreasing temperature, and to partial occlusion of the perforated area by corrosion products. 5 refs., 4 tabs

  20. Advocacy Disabled in Publishing Newspapers Media in Malaysia

    Directory of Open Access Journals (Sweden)

    Hazzlan Sama

    2017-07-01

    Full Text Available This article discusses the role of news media in communicating information about Disabled news to the public. The focus of the discussion centered issue and advocacy role of the news media conducted to understand the issues of persons with disabilities. Studies conducted using the method of analysis to systematically review the library of selected journals that conduct media exposure of persons with disabilities at the global level and so focused towards media conference in Malaysia. In this research, the data was obtained through databases ERIC, google scholar, Journal of Education, Journal of Social Sciences and Journal of Communication. A total of 30 articles were based on keywords such as disabled people, newspapers, news exposure to people with disabilities. However, researchers have obtained 13 articles that met after being filtered. The results obtained showed that the press releases are also still not open and not to report the news on disabilities. This is because there is a stigma that prevents acceptance of disabilities such as discrimination and negative attitudes towards them. Outlook negative stereotypes of people with disabilities who are strangers, the great ones, defects often appear in the media. Even now there is increasing advocacy for press media publishing news on this special group but the content or dissemination of information about them is still less show. Artikel ini membincangkan peranan media akhbar dalam menyampaikan maklumat berita tentang Orang Kurang Upaya kepada masyarakat. Fokus perbincangan ditumpukan isu dan peranan advokasi media akhbar dijalankan untuk memahami isu orang kurang upaya. Kajian yang dijalankan menggunakan kaedah analisis perpustakaan secara sistematik review terhadap jurnal-jurnal terpilih yang menjalankan kajian paparan media ke atas orang kurang upaya di peringkat global dan seterusnya difokus ke arah media akhbar di Malaysia. Dalam penyelidikan ini, data-data diperolehi melalui pengkalan

  1. Broad-Range Bacterial Capture from Fluid-Samples: Implications for Amplification-Free Contamination Detection

    Directory of Open Access Journals (Sweden)

    Monika WEBER

    2016-08-01

    Full Text Available Fluid-Screen, Inc. presents a bacterial concentration and filtration method based on dielectrophoresis and alternating current kinetics. Dielectrophoresis has been previously shown to induce particle motion; however, bacterial capture efficiency and reproducibility have consistently been low, reducing its potential for practical applications. In this study, we introduce a novel, patent-pending electrode system optimized to simultaneously capture a wide range of bacterial species from a variety of aqueous solutions. Specifically, we show that the method of dielectrophoresis used induces responses in both characteristic Gram- negative Escherichia coli and Gram-positive Enterococcus faecalis bacteria, as well as with Bacillus subtilis and Aestuariimicrobium kwangyangense. We have adapted the electrode design to create a bacterial sample preparatio unit, termed the sample sorter, that is able to capture multiple bacterial species and release them simultaneously for bacterial concentration and exchange from complex matrices to defined buffer media. This technology can be used on its own or in conjunction with standard bacterial detection methods such as mass spectroscopy. The Fluid-Screen product will dramatically improve testing and identification of bacterial contaminants in various industrial settings by eliminating the need for amplification of samples and by reducing the time to identification.

  2. A comparison of geochemical exploration techniques and sample media within accretionary continental margins: an example from the Pacific Border Ranges, Southern Alaska, U.S.A.

    Science.gov (United States)

    Sutley, S.J.; Goldfarb, R.J.; O'Leary, R. M.; Tripp, R.B.

    1990-01-01

    The Pacific Border Ranges of the southern Alaskan Cordillera are composed of a number of allochthonous tectonostratigraphic terranes. Within these terranes are widespread volcanogenic, massive sulfide deposits in and adjacent to portions of accreted ophiolite complexes, bands and disseminations of chromite in accreted island-arc ultramafic rocks, and epigenetic, gold-bearing quartz veins in metamorphosed turbidite sequences. A geochemical pilot study was undertaken to determine the most efficient exploration strategy for locating these types of mineral deposits within the Pacific Border Ranges and other typical convergent continental margin environments. High-density sediment sampling was carried out in first- and second-order stream channels surrounding typical gold, chromite and massive sulfide occurrences. At each site, a stream-sediment and a panned-concentrate sample were collected. In the laboratory, the stream sediments were sieved into coarse-sand, fine- to medium-sand, and silt- to clay-size fractions prior to analysis. One split of the panned concentrates was retained for analysis; a second split was further concentrated by gravity separation in heavy liquids and then divided into magnetic, weakly magnetic and nonmagnetic fractions for analysis. A number of different techniques including atomic absorption spectrometry, inductively coupled plasma atomic emission spectrometry and semi-quantitative emission spectrography were used to analyze the various sample media. Comparison of the various types of sample media shows that in this tectonic environment it is most efficient to include a silt- to clay-size sediment fraction and a panned-concentrate sample. Even with the relatively low detection limits for many elements by plasma spectrometry and atomic absorption spectrometry, anomalies reflecting the presence of gold veins could not be identified in any of the stream-sediment fractions. Unseparated panned-concentrate samples should be analyzed by emission

  3. Culture methods of allograft musculoskeletal tissue samples in Australian bacteriology laboratories.

    Science.gov (United States)

    Varettas, Kerry

    2013-12-01

    Samples of allograft musculoskeletal tissue are cultured by bacteriology laboratories to determine the presence of bacteria and fungi. In Australia, this testing is performed by 6 TGA-licensed clinical bacteriology laboratories with samples received from 10 tissue banks. Culture methods of swab and tissue samples employ a combination of solid agar and/or broth media to enhance micro-organism growth and maximise recovery. All six Australian laboratories receive Amies transport swabs and, except for one laboratory, a corresponding biopsy sample for testing. Three of the 6 laboratories culture at least one allograft sample directly onto solid agar. Only one laboratory did not use a broth culture for any sample received. An international literature review found that a similar combination of musculoskeletal tissue samples were cultured onto solid agar and/or broth media. Although variations of allograft musculoskeletal tissue samples, culture media and methods are used in Australian and international bacteriology laboratories, validation studies and method evaluations have challenged and supported their use in recovering fungi and aerobic and anaerobic bacteria.

  4. Deposition of Ibuprofen Crystals on Hydroxypropyl Cellulose/Polyacrylamide Gel: Experimental and Mathematic Modeling Releasing

    Directory of Open Access Journals (Sweden)

    Claudia Alicia Castillo-Miranda

    2016-01-01

    Full Text Available The crystallization of nonsteroidal anti-inflammatory drug [2-(4-isobutyl-phenyl propionic acid] ibuprofen (IBP on a hydroxypropyl cellulose (HPC and polyacrylamide (PAAm gel was studied as well as the release kinetics of the drug. The IBP was crystallized on the gel surface of HPC/PAAm. It had a prismatic shape and the growth was made in an aqueous medium; the crystallinity grade of the gels HPC/PAAm and HPC/PAAm-IBU increased to 68% and to 58%, respectively. The release of IBP is performed by two means: by a non-Fickian diffusion process and by relaxation of the chains of the gel; without regard to temperature and the diffusion media, this correlates with the lower critical solution temperature (LCST of the proposed gel. This polymer matrix provides an option for releasing nonsteroidal anti-inflammatory drugs in a temperature range of 35–39°C. Korsmeyer and Peppas mathematical model was simulated for data releases, statistically significant at 95% confidence level.

  5. Microbubbles-Assisted Ultrasound Triggers the Release of Extracellular Vesicles

    Directory of Open Access Journals (Sweden)

    Yuana Yuana

    2017-07-01

    Full Text Available Microbubbles-assisted ultrasound (USMB has shown promise in improving local drug delivery. The formation of transient membrane pores and endocytosis are reported to be enhanced by USMB, and they contribute to cellular drug uptake. Exocytosis also seems to be linked to endocytosis upon USMB treatment. Based on this rationale, we investigated whether USMB triggers exocytosis resulting in the release of extracellular vesicles (EVs. USMB was performed on a monolayer of head-and-neck cancer cells (FaDu with clinically approved microbubbles and commonly used ultrasound parameters. At 2, 4, and 24 h, cells and EV-containing conditioned media from USMB and control conditions (untreated cells, cells treated with microbubbles and ultrasound only were harvested. EVs were measured using flow cytometric immuno-magnetic bead capture assay, immunogold electron microscopy, and western blotting. After USMB, levels of CD9 exposing-EVs significantly increased at 2 and 4 h, whereas levels of CD63 exposing-EVs increased at 2 h. At 24 h, EV levels were comparable to control levels. EVs released after USMB displayed a heterogeneous size distribution profile (30–1200 nm. Typical EV markers CD9, CD63, and alix were enriched in EVs released from USMB-treated FaDu cells. In conclusion, USMB treatment triggers exocytosis leading to the release of EVs from FaDu cells.

  6. PENGGUNAAN MEDIA PEMBELAJARAN MICROSOFT OFFICE POWERPOINT PADA POKOK BAHASAN PELUANG

    Directory of Open Access Journals (Sweden)

    author Rahma Faelasofi

    2015-01-01

    Full Text Available The objectives of this research was to solve how to increase the students’ average result especially on the subject of Opportunities. This study aims to determine whether the students’ average result of the student Mathematic Education Department STKIP Muhammadiyah Pringsewu Lampung (STKIP MPL in the academic year of 2013-2014 using instructional teaching media using Microsoft Office PowerPoint on the subject of Opportunities, is better than the students’ average result without using instructional teaching media using Microsoft Office PowerPoint. This research is a quantitative approach, with a quasi-experimental research methods. The population was all of the students in third grade of the Mathematic Education Department STKIP MPL in the academic year of 2013-2014. The samples of the research were taken by using the cluster random sampling technique. Based on hypothesis test, it can be included that: 1 there are differences in students’ average results between experiment class that used computer teaching media using Microsoft Office PowerPoint and the kontrol class without using a computer teaching media using Microsoft Office PowerPoint; 2 the students’ average results at experiment class that used a computer teaching media using Microsoft Office PowerPoint higher than the students’ average results in kontrol class.Keywords: Teaching Media, Microsoft Office PowerPoint, Subject of Opportunities

  7. Characteristics associated with media use in early adolescence

    Directory of Open Access Journals (Sweden)

    José Godinho

    2014-03-01

    Full Text Available This study aimed to identify socioeconomic and behavioral characteristics associated with media use in early adolescence. The sample was comprised of 1,680 adolescents (884 girls and 796 boys aged 13, attending private and public schools in Porto, Portugal, during 2003/2004. Adolescents completed questionnaires pertaining to demographic, social and behavioral characteristics, including the time spent watching television and playing computer games on week and weekend days. Logistic and proportional ordinal regressions showed that attending public schools, sleeping less time, using tobacco and presenting low levels of physical activity were factors associated with high media use. In boys living with one of their parents as well as living with younger and older parents were also associated with high media use. Besides the association with less healthier behaviours, we also found higher media use among adolescents from lower social classes and less structured families, which may increase their exposure to negative influence of the media.

  8. Characteristics associated with media use in early adolescence.

    Science.gov (United States)

    Godinho, José; Araújo, Joana; Barros, Henrique; Ramos, Elisabete

    2014-03-01

    This study aimed to identify socioeconomic and behavioral characteristics associated with media use in early adolescence. The sample was comprised of 1,680 adolescents (884 girls and 796 boys) aged 13, attending private and public schools in Porto, Portugal, during 2003/2004. Adolescents completed questionnaires pertaining to demographic, social and behavioral characteristics, including the time spent watching television and playing computer games on week and weekend days. Logistic and proportional ordinal regressions showed that attending public schools, sleeping less time, using tobacco and presenting low levels of physical activity were factors associated with high media use. In boys living with one of their parents as well as living with younger and older parents were also associated with high media use. Besides the association with less healthier behaviours, we also found higher media use among adolescents from lower social classes and less structured families, which may increase their exposure to negative influence of the media.

  9. Fluoride releasing and enamel demineralization around orthodontic brackets by fluoride-releasing composite containing nanoparticles.

    Science.gov (United States)

    Melo, Mary A S; Morais, Weslanny A; Passos, Vanara F; Lima, Juliana P M; Rodrigues, Lidiany K A

    2014-05-01

    Fluoride-containing materials have been suggested to control enamel demineralization around orthodontic brackets during the treatment with fixed appliances. The improvement of their properties has been made through innovations, such as the application of nanotechnology by incorporation of nanofillers. This in vitro study evaluated the capacity of fluoride releasing and enamel demineralization inhibition of fluoride-releasing nanofilled cement around orthodontic brackets using an artificial caries biofilm model. Forty bovine enamel discs were selected by evaluating surface microhardness and randomized into four groups (n = 10): non-fluoride-releasing microfilled composite, fluoride-releasing microfilled composite, resin-modified glass ionomer cement (RMGI), and fluoride-releasing nanofilled composite (FN). After brackets bonding in each disc, the specimens were subjected to a cariogenic challenge through a Streptococcus mutans biofilm model. After the experimental period, the biofilm formed around the brackets was collected for fluoride analysis and the mineral loss around the brackets was determined by integrated demineralization via cross-sectional microhardness measurement at 20 and 70 μm from the bracket margin. Additionally, samples of each group were subjected to energy-dispersive X-ray spectroscopy (EDX) analysis examined under a scanning electron microscopy (SEM). ANOVA followed by Tukey test were applied for fluoride concentration and mineral loss data, respectively. At both distances, only RMGI statistically differed from the other groups presenting the lowest demineralization, although there was a trend to a lower demineralization of enamel around brackets in FN group. Similar condition was found to fluoride concentration and EDX/SEM analysis. Under the cariogenic exposure condition of this study, the fluoride-releasing nanofilled material had similar performance to fluoride-releasing microfilled materials. The presence of nanofillers in the fluoride-releasing

  10. Do Dietary Habits Influence Trace Elements Release from Fixed Orthodontic Appliances?

    Science.gov (United States)

    Wołowiec, Paulina; Chojnacka, Katarzyna; Loster, Bartłomiej W; Mikulewicz, Marcin

    2017-12-01

    The objective was to investigate the effect of dietary habits on the release of Cr and Ni ions from orthodontic appliances by hair mineral analysis. Patients (N = 47) underwent electronic questionnaire survey to investigate the effect of dietary habits on Cr and Ni levels in hair. The research was carried out on hair sampled at the beginning and in the 4th, 8th, and 12th months of the treatment. The content of Cr and Ni in the collected samples was determined by ICP-OES. The study showed that consumption of acidic dietary products may have the effect on increasing the release of Cr and Ni ions from orthodontic appliances. The release of Cr from orthodontic appliances in patients who consumed fruit juice, coffee, yoghurt, and vinegar was higher. The coefficients enabling comparison of metal ions release pattern at a given sampling points were defined. The comparison of the coefficients yielded the information on the possible magnification of metal ions released as the result of the additional factor consumption of acidic food or drink that intensifies metal ions release. The following magnification pattern was found for chromium: coffee (7.57 times) > yoghurt (2.53) > juice (1.86) > vinegar (1.08), and for nickel: vinegar (2.2) > coffee (1.22) > juice (1.05). Yoghurt did not intensify the release of nickel. Concluding, orthodontic patients should avoid drinking/eating coffee, yoghurt, fruit juices, and vinegar.

  11. The preparation and the sustained release of titanium dioxide hollow particles encapsulating L-ascorbic acid

    Science.gov (United States)

    Tominaga, Yoko; Kadota, Kazunori; Shimosaka, Atsuko; Yoshida, Mikio; Oshima, Kotaro; Shirakawa, Yoshiyuki

    2018-05-01

    The preparation of the titanium dioxide hollow particles encapsulating L-ascorbic acid via sol-gel process using inkjet nozzle has been performed, and the sustained release and the effect protecting against degradation of L-ascorbic acid in the particles were investigated. The morphology of titanium dioxide particles was evaluated by scanning electron microscopy (SEM) and energy dispersive X-ray spectrometry (EDS). The sustained release and the effect protecting against degradation of L-ascorbic acid were estimated by dialysis bag method in phosphate buffer saline (PBS) (pH = 7.4) as release media. The prepared titanium dioxide particles exhibited spherical porous structures. The particle size distribution of the titanium dioxide particles was uniform. The hollow titanium dioxide particles encapsulating L-ascorbic acid showed the sustained release. It was also found that the degradation of L-ascorbic acid could be inhibited by encapsulating L-ascorbic acid in the titanium dioxide hollow particles.

  12. Correlations in metal release profiles following sorption by Lemna minor.

    Science.gov (United States)

    Üçüncü Tunca, Esra; Ölmez, Tolga T; Özkan, Alper D; Altındağ, Ahmet; Tunca, Evren; Tekinay, Turgay

    2016-08-02

    Following the rapid uptake of contaminants in the first few hours of exposure, plants typically attempt to cope with the toxic burden by releasing part of the sorbed material back into the environment. The present study investigates the general trends in the release profiles of different metal(loid)s in the aquatic macrophyte Lemna minor and details the correlations that exist between the release of metal(loid) species. Water samples with distinct contamination profiles were taken from Nilüfer River (Bursa, Turkey), Yeniçağa Lake (Bolu, Turkey), and Beyşehir Lake (Konya, Turkey) and used for release studies; 36 samples were tested in total. Accumulation and release profiles were monitored over five days for 11 metals and a metalloid ((208)Pb, (111)Cd, (52)Cr,(53)Cr,(60)Ni,(63)Cu,(65)Cu,(75)As,(55)Mn, (137)Ba, (27)Al, (57)Fe, (66)Zn,(68)Zn) and correlation, cluster and principal component analyses were employed to determine the factors that affect the release of these elements. Release profiles of the tested metal(loid)s were largely observed to be distinct; however, strong correlations have been observed between certain metal pairs (Cr/Ni, Cr/Cu, Zn/Ni) and principal component analysis was able to separate the metal(loid)s into three well-resolved groups based on their release.

  13. In-Vitro Release of Ketoprofen Behavior Loaded in Polyvinyl Alcohol / Acrylamide Hydrogels Prepared by Gamma Irradiation

    International Nuclear Information System (INIS)

    Mahmoud, Gh.A.; Hegazy, D.E.; Kamal, H.

    2014-01-01

    Hydrogels based on various ratios of polyvinyl alcohol (PVA) and acrylamide (AAm) were prepared by gamma radiation. The formed hydrogels were characterized by spectroscopic analysis (FTIR), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and swelling studied. It was found that the thermal stability of the hydrogel decreases as the AAm content increases in the hydrogel. The higher the AAm content in the hydrogel, the lower the values of Tm and ΔH m . Ketoprofen was adopted as a model drug to study the adsorption and release behavior of (PVA/AAm) hydrogel. The drug adsorption was decreased by increasing AAm ratio in the hydrogel. From the in vitro drug release study in ph progressive media, the basic medium was showed comparatively the highest release and the (PVA/AAm) hydrogel of composition (70/30) was found to be the highest release one. The mechanism of Ketoprofen release from the (PVA/AAm) matrix was found to be non-Fickian mechanism for all investigated hydrogels at ph 7.

  14. Women Journalists Working Conditions and Their Suitability in the Media

    Directory of Open Access Journals (Sweden)

    R. Sasikala

    2016-05-01

    technique. The sample frame for the study includes both male and female journalists of print and electronic media. The respondents comprised of editors, sub- editors, reporters, programme executives and free lancers in both print and electronic media. The data was obtained using the questionnaire and it was analyzed using percentage analysis method. The findings reveals that women journalists are encouraged and given freedom to organize their work and do not face major discrimination in their working spot on the basis of gender and they are also given decision – making position in the media and their positions in the media is satisfactory. Regarding, importance given for women issues in the media, both men and women journalist consider women issues as one of the important issue and women issues are portrayed adequately in the media.

  15. The effect of aqueous media on the mechanical properties of fluorapatite-mullite glass-ceramics.

    Science.gov (United States)

    Mollazadeh, S; Ajalli, Siamak; Kashi, Tahereh S Jafarzadeh; Yekta, Bijan Eftekhai; Javadpour, Jafar; Jafari, S; Youssefi, Abbas; Fazel, Akbar

    2015-11-01

    To verify the effects of alternating thermal changes in aqueous media and chemical composition on mechanical properties of apatite-mullite glass-ceramics and to investigate concentration of ions eluted from glass-ceramics in aqueous media. The glass compositions were from SiO2Al2O3P2O5CaOTiO2BaOZrO2CaF2 system. Glass-ceramics were prepared by heat-treating at 1100°C for 3h samples alternately immersed in water at 5 and 60°C. The 3-point bending strength (n=10) were determined using 3×4×25mm/bar and a universal testing machine, at a cross-head speed of 0.1mm/min. Vickers micro hardness were evaluated by applying a total of 15-20 indentations under a 100g load for 30s. Concentrations of ions eluted from glass-ceramics immersed in 60±5°C double distilled water were determined by ion chromatography. The toxicity of glass-ceramics was assessed by seeding the osteosarcoma cells (MG63) on powder for different days and their cell proliferation assessment was investigated by MTT assay. The data were analyzed using one way analysis of variance and the means were compared by Tukey's test (5% significance level). The highest flexural strength and hardness values after thermal changes belonged to TiO2 and ZrO2 containing glass-ceramics which contained lower amount of released ions. BaO containing glass-ceramic and sample with extra amount of silica showed the highest amount of reduction in their mechanical strength values. These additives enhanced the concentration of eluted ions in aqueous media. MTT results showed that glass-ceramics were almost equivalent concerning their in-vitro biological behavior. Thermal changes and chemical compositions had significant effects on flexural strength and Vickers micro-hardness values. Copyright © 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  16. Media identities and media-influenced indentifications Visibility and identity recognition in the media

    Directory of Open Access Journals (Sweden)

    Víctor Fco. Sampedro Blanco

    2004-10-01

    Full Text Available The media establish, in large part, the patterns of visibility and public recognition of collective identities. We define media identities as those that are the object of production and diffusion by the media. From this discourse, the communities and individuals elaborate media-influenced identifications; that is, processes of recognition or banishment; (rearticulating the identity markers that the media offer with other cognitive and emotional sources. The generation and appropriation of the identities are subjected to a media hierarchisation that influences their normalisation or marginalisation. The identities presented by the media and assumed by the audience as part of the official, hegemonic discourse are normalised, whereas the identities and identifications formulated in popular and minority terms are marginalised. After presenting this conceptual and analytical framework, this study attempts to outline the logics that condition the presentation, on the one hand, andthe public recognition, on the other hand, of contemporary identities.

  17. Self-Replenishing Vascularized Fouling-Release Surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Howell, C; Vu, TL; Lin, JJ; Kolle, S; Juthani, N; Watson, E; Weaver, JC; Alvarenga, J; Aizenberg, J

    2014-08-13

    Inspired by the long-term effectiveness of living antifouling materials, we have developed a method for the self-replenishment of synthetic biofouling-release surfaces. These surfaces are created by either molding or directly embedding 3D vascular systems into polydimethylsiloxane (PDMS) and filling them with a silicone oil to generate a nontoxic oil-infused material. When replenished with silicone oil from an outside source, these materials are capable of self-lubrication and continuous renewal of the interfacial fouling-release layer. Under accelerated lubricant loss conditions, fully infused vascularized samples retained significantly more lubricant than equivalent nonvascularized controls. Tests of lubricant-infused PDMS in static cultures of the infectious bacteria Staphylococcus aureus and Escherichia coli as well as the green microalgae Botryococcus braunii, Chlamydomonas reinhardtii, Dunaliella sauna, and Nannochloropsis oculata showed a significant reduction in biofilm adhesion compared to PDMS and glass controls containing no lubricant. Further experiments on vascularized versus nonvascularized samples that had been subjected to accelerated lubricant evaporation conditions for up to 48 h showed significantly less biofilm adherence on the vascularized surfaces. These results demonstrate the ability of an embedded lubricant-filled vascular network to improve the longevity of fouling-release surfaces.

  18. In vitro gentamicin release from commercially available calcium-phosphate bone substitutes influence of carrier type on duration of the release profile

    Directory of Open Access Journals (Sweden)

    Bronckers Antonius LJJ

    2006-02-01

    Full Text Available Abstract Background Polymethyl-methacrylate (PMMA beads releasing antibiotics are used extensively to treat osteomyelitis, but require surgical removal afterwards because they do not degrade. Methods As an alternative option, this report compares the in vitro gentamicin release profile from clinically used, biodegradable carrier-materials: six injectable cements and six granule-types. Cement cylinders and coated granules containing 3% gentamicin were submerged in dH2O and placed in a 48-sample parallel drug-release system. At regular intervals (30, 90, 180 min. and then every 24 h, for 21 days, the release fluid was exchanged and the gentamicin concentration was measured. The activity of released gentamicin was tested on Staphylococcus aureus. Results All combinations showed initial burst-release of active gentamicin, two cements had continuous-release (17 days. The relative release of all cements (36–85% and granules (30–62% was higher than previously reported for injectable PMMA-cements (up to 17% and comparable to other biodegradable carriers. From the cements residual gentamicin could be extracted, whereas the granules released all gentamicin that had adhered to the surface. Conclusion The high release achieved shows great promise for clinical application of these biodegradable drug-carriers. Using the appropriate combination, the required release profile (burst or sustained may be achieved.

  19. Long-term relations among prosocial-media use, empathy, and prosocial behavior.

    Science.gov (United States)

    Prot, Sara; Gentile, Douglas A; Anderson, Craig A; Suzuki, Kanae; Swing, Edward; Lim, Kam Ming; Horiuchi, Yukiko; Jelic, Margareta; Krahé, Barbara; Liuqing, Wei; Liau, Albert K; Khoo, Angeline; Petrescu, Poesis Diana; Sakamoto, Akira; Tajima, Sachi; Toma, Roxana Andreea; Warburton, Wayne; Zhang, Xuemin; Lam, Ben Chun Pan

    2014-02-01

    Despite recent growth of research on the effects of prosocial media, processes underlying these effects are not well understood. Two studies explored theoretically relevant mediators and moderators of the effects of prosocial media on helping. Study 1 examined associations among prosocial- and violent-media use, empathy, and helping in samples from seven countries. Prosocial-media use was positively associated with helping. This effect was mediated by empathy and was similar across cultures. Study 2 explored longitudinal relations among prosocial-video-game use, violent-video-game use, empathy, and helping in a large sample of Singaporean children and adolescents measured three times across 2 years. Path analyses showed significant longitudinal effects of prosocial- and violent-video-game use on prosocial behavior through empathy. Latent-growth-curve modeling for the 2-year period revealed that change in video-game use significantly affected change in helping, and that this relationship was mediated by change in empathy.

  20. The impact of ion exchange media and filters on LLW processing

    International Nuclear Information System (INIS)

    James, K.L.; Miller, C.C.

    1992-01-01

    Optimized ion exchange media at Diablo Canyon have steadily improved the treatment of radioactive liquid waste. The activity released to the environment has been reduced while simultaneously reducing the volume of solid radwaste generated from processing radioactive liquids. This has lowered the liquid waste processing costs and reduced the number of radioactive shipments from the plant. A cobalt treatment technique was identified and successfully implemented prior to reactor coolant chemistry alteration. A cesium treatment using zeolite has been successfully implemented. A cobalt removal treatment, combining series cation ion exchange with submicron filtration, has successfully removed cobalt after reactor coolant chemistry alteration. A new carbon-based material will be monitored to find a media to remove cobalt from high-conductivity liquids. (author)

  1. Hybrid nanostructured drug carrier with tunable and controlled drug release

    International Nuclear Information System (INIS)

    Depan, D.; Misra, R.D.K.

    2012-01-01

    We describe here a transformative approach to synthesize a hybrid nanostructured drug carrier that exhibits the characteristics of controlled drug release. The synthesis of the nanohybrid architecture involved two steps. The first step involved direct crystallization of biocompatible copolymer along the long axis of the carbon nanotubes (CNTs), followed by the second step of attachment of drug molecule to the polymer via hydrogen bonding. The extraordinary inorganic–organic hybrid architecture exhibited high drug loading ability and is physically stable even under extreme conditions of acidic media and ultrasonic irradiation. The temperature and pH sensitive characteristics of the hybrid drug carrier and high drug loading ability merit its consideration as a promising carrier and utilization of the fundamental aspects used for synthesis of other promising drug carriers. The higher drug release response during the application of ultrasonic frequency is ascribed to a cavitation-type process in which the acoustic bubbles nucleate and collapse releasing the drug. Furthermore, the study underscores the potential of uniquely combining CNTs and biopolymers for drug delivery. - Graphical abstract: Block-copolymer crystallized on carbon nanotubes (CNTs). Nanohybrid drug carrier synthesized by attaching doxorubicin (DOX) to polymer crystallized CNTs. Crystallized polymer on CNTs provide mechanical stability. Triggered release of DOX. Highlights: ► The novel synthesis of a hybrid nanostructured drug carrier is described. ► The drug carrier exhibits high drug loading ability and is physically stable. ► The high drug release is ascribed to a cavitation-type process.

  2. Surface characteristics, copper release, and toxicity of nano- and micrometer-sized copper and copper(II) oxide particles: a cross-disciplinary study.

    OpenAIRE

    Midander, Klara; Cronholm, Pontus; Karlsson, Hanna L.; Elihn, Karine; Moller, Lennart; Leygraf, Christofer; Wallinder, Inger Odnevall

    2009-01-01

    An interdisciplinary and multianalytical research effort is undertaken to assess the toxic aspects of thoroughly characterized nano- and micrometer-sized particles of oxidized metallic copper and copper(II) oxide in contact with cultivated lung cells, as well as copper release in relevant media. All particles, except micrometer-sized Cu, release more copper in serum-containing cell medium (supplemented Dulbecco's minimal essential medium) compared to identical exposures in phosphate-buffered ...

  3. Komunikasi Krisis di Era New Media dan Social Media

    OpenAIRE

    Prastya, Narayana Mahendra

    2016-01-01

    New media and social media have changed the practice of public relations. One area that changed is crisis communication. Because of these new technologies, crisis can be more complex. The pace of information, the uncertainty, and the rumors, are increasing. Public relations practitioners should include the new media and social media use in their crisis communication plan. Before doing that, public relations practitioners should change their mindset about social media and new media. The first ...

  4. Vapor and gas sampling of single-shell tank 241-BX-110 using the in situ vapor sampling system

    International Nuclear Information System (INIS)

    Lockrem, L.L.

    1997-01-01

    The Vapor Issue Resolution Program tasked the Vapor Team (the team) to collect representative headspace samples from Hanford Site single-shell tank (SST) 241-BX-110. This document presents sampling data resulting from the April 30, 1996 sampling of SST 241-BX-110. Analytical results will be presented in a separate report issued by Pacific Northwest National Laboratory (PNNL), which supplied and analyzed the sampling media

  5. Social comparisons with media images are cognitively inefficient even for women who say they feel pressure from the media.

    Science.gov (United States)

    Want, Stephen C; Saiphoo, Alyssa

    2017-03-01

    The present study investigated whether social comparisons with media images are cognitively efficient (demanding minimal mental effort) or cognitively effortful processes, in a sample of female undergraduate students (N=151) who reported feeling pressure from the media regarding their appearance. Two groups were shown 12 images of thin and attractive female models. One group was asked to memorize a complex 8-digit number during exposure to the images (Cognitively Busy condition), while the other memorized a much simpler number (Free View condition). A third group (Control condition) viewed images without people. Participants in the Free View condition demonstrated significantly increased negative mood and lowered appearance satisfaction from before to after exposure, while participants in the Cognitively Busy and Control conditions did not. We argue that these results suggest social comparisons with media images are at least somewhat cognitively effortful even among women who say they feel pressure from the media. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Riola release report

    Energy Technology Data Exchange (ETDEWEB)

    Woodward, E.C.

    1983-08-04

    Eleven hours after execution of the Riola Event (at 0826 PDT on 25 September 1980) in hole U2eq of the Nevada Test Site (NTS), a release of radioactivity began. When the seepage stopped at about noon the following day, up to some 3200 Ci of activity had been dispersed by light variable winds. On 26 September, examination of the geophone records showed six hours of low-level, but fairly continuous, activity before the release. Electrical measurements indicated that most cables were still intact to a depth below the stemming platform. A survey of the ground zero area showed that the seepage came through cracks between the surface conductor and the pad, through cracks in the pad, and through a crack adjacent to the pad around the mousehole (a small hole adjacent to the emplacement hole). To preclude undue radiation exposure or injury from a surprise subsidence, safety measures were instituted. Tritium seepage was suffucient to postpone site activities until a box and pipeline were emplaced to contain and remove the gas. Radiation release modeling and calculations were generally consistent with observations. Plug-hole interaction calculations showed that the alluvium near the bottom of the plug may have been overstressed and that improvements in the design of the plug-medium interface can be made. Experimental studies verified that the surface appearance of the plug core was caused by erosion, but, assuming a normal strength for the plug material, that erosion alone could not account for the disappearance of such a large portion of the stemming platform. Samples from downhole plug experiments show that the plug may have been considerably weaker than had been indicted by quality assurance (QA) samples. 19 references, 32 figures, 10 tables.

  7. Riola release report

    International Nuclear Information System (INIS)

    Woodward, E.C.

    1983-01-01

    Eleven hours after execution of the Riola Event (at 0826 PDT on 25 September 1980) in hole U2eq of the Nevada Test Site (NTS), a release of radioactivity began. When the seepage stopped at about noon the following day, up to some 3200 Ci of activity had been dispersed by light variable winds. On 26 September, examination of the geophone records showed six hours of low-level, but fairly continuous, activity before the release. Electrical measurements indicated that most cables were still intact to a depth below the stemming platform. A survey of the ground zero area showed that the seepage came through cracks between the surface conductor and the pad, through cracks in the pad, and through a crack adjacent to the pad around the mousehole (a small hole adjacent to the emplacement hole). To preclude undue radiation exposure or injury from a surprise subsidence, safety measures were instituted. Tritium seepage was suffucient to postpone site activities until a box and pipeline were emplaced to contain and remove the gas. Radiation release modeling and calculations were generally consistent with observations. Plug-hole interaction calculations showed that the alluvium near the bottom of the plug may have been overstressed and that improvements in the design of the plug-medium interface can be made. Experimental studies verified that the surface appearance of the plug core was caused by erosion, but, assuming a normal strength for the plug material, that erosion alone could not account for the disappearance of such a large portion of the stemming platform. Samples from downhole plug experiments show that the plug may have been considerably weaker than had been indicted by quality assurance (QA) samples. 19 references, 32 figures, 10 tables

  8. Have Economic Educators Embraced Social Media as a Teaching Tool?

    Science.gov (United States)

    Al-Bahrani, Abdullah; Patel, Darshak; Sheridan, Brandon J.

    2017-01-01

    In this article, the authors discuss the results of a study of the perceptions of a national sample of economics faculty members from various institutions regarding the use of social media as a teaching tool in and out of the economics classroom. In the past few years, social media has become globally popular, and its use is ubiquitous among…

  9. Longitudinal Effects of Violent Media Usage on Aggressive Behavior—The Significance of Empathy

    Directory of Open Access Journals (Sweden)

    Thomas Mößle

    2014-02-01

    Full Text Available The aim of this study was to thoroughly investigate the link between violent media consumption and aggressive behavior. Using a large longitudinal student sample, the role of empathy as a possible mediator of this relationship was of special interest. Data were drawn from wave three to five of the Berlin Longitudinal Study Media, a four-year longitudinal control group study with 1207 school children. Participants completed measures of media usage (violent content of TV and computer games, aggressive behavior perpetration, and empathy. The average age of participants was 10.4 years at Time 1 and 12.4 years at Time 3. Half of the study sample was male (50%. Trivariate structural equation modeling using three measurement times were conducted for assessing the role of empathy as a mediator of the longitudinal relationship between the usage of violent media content and aggressive behavior. For male students empathic skills were shown to unfold a key mediating role between problematic media usage and aggressive behavior.

  10. Metal contamination in environmental media in residential ...

    Science.gov (United States)

    Hard-rock mining for metals, such as gold, silver, copper, zinc, iron and others, is recognized to have a significant impact on the environmental media, soil and water, in particular. Toxic contaminants released from mine waste to surface water and groundwater is the primary concern, but human exposure to soil contaminants either directly, via inhalation of airborne dust particles, or indirectly, via food chain (ingestion of animal products and/or vegetables grown in contaminated areas), is also, significant. In this research, we analyzed data collected in 2007, as part of a larger environmental study performed in the Rosia Montana area in Transylvania, to provide the Romanian governmental authorities with data on the levels of metal contamination in environmental media from this historical mining area. The data were also considered in policy decision to address mining-related environmental concerns in the area. We examined soil and water data collected from residential areas near the mining sites to determine relationships among metals analyzed in these different environmental media, using the correlation procedure in SAS statistical software. Results for residential soil and water analysis indicate that the average values for arsenic (As) (85 mg/kg), cadmium (Cd) (3.2 mg/kg), mercury (Hg) (2.3 mg/kg) and lead (Pb) (92 mg/kg) exceeded the Romanian regulatory exposure levels [the intervention thresholds for residential soil in case of As (25 mg/kg) and Hg

  11. Media education and media enlightenment as attributes of information society

    Directory of Open Access Journals (Sweden)

    Лилия Борисовна Белоглазова

    2014-12-01

    Full Text Available The article deals with the problem of the functioning of media-education and media-enlightenment in modern society. Focuses on the impact of this socio-cultural phenomenon on consciousness of members of the Information Society. Are the main characteristics of media-education and media-education and media-enlightenment. Concludes that media-education and media-enlightenment forms unscientific and anti-scientific thinking and style speech.

  12. Linking dissolution to disintegration in immediate release tablets using image analysis and a population balance modelling approach.

    Science.gov (United States)

    Wilson, David; Wren, Stephen; Reynolds, Gavin

    2012-01-01

    In order to achieve an improved understanding of disintegration and dissolution phenomena for an immediate release tablet formulation, a technique to monitor the number and size of particles entrained within the dissolution media was developed in combination with a population balancing model. Tablets were first characterized for crushing force, disintegration time and dissolution performance using standard USP methodologies. The performance of the tablets was then assessed using a new measurement system which links a "QicPic" particle imaging device to a USP dissolution vessel. This system enables us to measure the number and size of particles generated during tablet dissolution. The population balance mathematical model allowed a tablet erosion rate to be manipulated to fit the experimental data. Results showed that tablets with differing crushing forces showed different dissolution behaviors that could be explained by differing rates of particle release into the dissolution media. These behaviors were then successfully modeled to provide a description of the dissolution and disintegration behavior of the tablets in terms of a tablet erosion rate. A new approach was developed that allowed the description of the dissolution behaviors of the tablets in terms of the rate that they release particles into solution. This was then successfully modeled in terms of a tablet erosion rate.

  13. Tritium adsorption/release behaviour of advanced EU breeder pebbles

    Science.gov (United States)

    Kolb, Matthias H. H.; Rolli, Rolf; Knitter, Regina

    2017-06-01

    The tritium loading of current grades of advanced ceramic breeder pebbles with three different lithium orthosilicate (LOS)/lithium metatitanate (LMT) compositions (20-30 mol% LMT in LOS) and pebbles of EU reference material, was performed in a consistent way. The temperature dependent release of the introduced tritium was subsequently investigated by temperature programmed desorption (TPD) experiments to gain insight into the desorption characteristics. The obtained TPD data was decomposed into individual release mechanisms according to well-established desorption kinetics. The analysis showed that the pebble composition of the tested samples does not severely change the release behaviour. Yet, an increased content of lithium metatitanate leads to additional desorption peaks at medium temperatures. The majority of tritium is released by high temperature release mechanisms of chemisorbed tritium, while the release of physisorbed tritium is marginal in comparison. The results allow valuable projections for the tritium release behaviour in a fusion blanket.

  14. Evaluation of contrast media submitted to ionizing radiation

    International Nuclear Information System (INIS)

    Pinho, Katia Elisa Prus; Gewehr, Pedro Miguel; Soboll, Danyel Scheidegger; Silva, Caroline Werner Pereira da; Barison, Andersson; Tilly Junior, Joao Gilberto

    2009-01-01

    Objective: the purpose of the present study was to investigate the influence of ionizing radiation from x-rays and gamma rays on the molecular structure stability of several radiologic contrast media employed in diagnostic imaging by means of 1 H and 1 3C nuclear magnetic resonance spectroscopy. Materials and methods: eight different types of iodinated contrast media (three ionic and five non-ionic) were exposed to x-rays and gamma rays irradiation. Subsequently, the 1 H and 1 3C{ 1 H} nuclear magnetic resonance spectra of these contrast media were collected. Results: the 1 H and 1 3C{ 1 H} nuclear magnetic resonance spectra of both ionic and non-ionic contrast media irradiated by x-rays or gamma rays demonstrated the absence of any alteration of the contrast media chemical composition. Conclusion: there is no problem in keeping contrast media inside examination rooms or close to radiological equipment. It is important to mention that, during the tests, the samples were directly irradiated, while in a radiology examination room, the irradiation is not direct and, therefore, radiation levels in these cases are much lower than those employed in the present study. (author)

  15. Islamophobia and Media Representation of Refugees in Serbia

    Directory of Open Access Journals (Sweden)

    Bojan Perovic

    2016-11-01

    Full Text Available This article seeks to respond to the following questions: How do the print media in Serbia report on refugees, asylum-seekers and refugee affairs; what effect is achieved through this type of media representation; and is there “Islamophobia pushing” through media. In the course of the media analysis this study examined various national dailies as well as the leading websites during the year of 2015 by focusing on specific articles that are able to contribute to the overall aim of the study. A total of eight Serbian newspapers were sampled: Alo, Informer, Kurir, Pravda, Telegraf, Danas, Politika and Blic as well as various leading websites. Although the wars in the former Yugoslavia ended twenty years ago, consequences of these wars are still visible in the Western Balkans and as will be demonstrated on the case study of Serbia in particular. In the past Islamophobic incidents in Serbia, a post-conflict society, were not rare. Islamophobic incidents to some extent are still present in Serbia, especially in the areas of paramount importance such as the media and therefore this phenomenon will also be analyzed in the context of media representation.

  16. Assessing the loading and release of metronidazole from bacterial cellulose film as a pharmaceutical dressing

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Salehi

    2017-08-01

    Full Text Available Background: Bacterial cellulose membrane (BCM produced by Gluconacetobacter xylinus is an advantageous bacterial product and because of its unique properties could be used as an ideal dressing. The aim of this study was to consider the capability of this biomaterial in the release of Metronidazole. In the case of proving this capability, it provides the basis for the production of a dressing containing this type of antibiotic. Materials and Methods: In this study, BCM was initially synthesized by Gluconacetobacter xylinus. The BCM was loaded by Metronidazole. Then the release process was considered in distilled water and buffer phosphate Saline. The ultra violet spectrophotometry was applied for measuring the concentration of the released drug. Results: The chemical structure of bacterial cellulose was confirmed by Fourier Transform Infrared (FT-IR spectroscopy. The release of Metronidazole in distilled water and phosphate buffered Saline was reached to 84.27% and 84.71%, respectively. Due to higher release in phosphate buffered Saline media, it seems that the trend of release in vitro provides efficient results. Conclusion: Results of this study provides the basis for future research on supplying an ideal dressing from this microbial product.

  17. Development of controlled release formulations of azadirachtin-A employing poly(ethylene glycol) based amphiphilic copolymers.

    Science.gov (United States)

    Kumar, Jitendra; Shakil, Najam A; Singh, Manish K; Singh, Mukesh K; Pandey, Alka; Pandey, Ravi P

    2010-05-01

    Controlled release (CR) formulations of azadirachtin-A, a bioactive constituent derived from the seed of Azadirachta indica A. Juss (Meliaceae), have been prepared using commercially available polyvinyl chloride, polyethylene glycol (PEG) and laboratory synthesized poly ethylene glycol-based amphiphilic copolymers. Copolymers of polyethylene glycol and various dimethyl esters, which self assemble into nano micellar aggregates in aqueous media, have been synthesized. The kinetics of azadirachtin-A, release in water from the different formulations was studied. Release from the commercial polyethylene glycol (PEG) formulation was faster than the other CR formulations. The rate of release of encapsulated azadirachtin-A from nano micellar aggregates is reduced by increasing the molecular weight of PEG. The diffusion exponent (n value) of azadirachtin-A, in water ranged from 0.47 to 1.18 in the tested formulations. The release was diffusion controlled with a half release time (t(1/2)) of 3.05 to 42.80 days in water from different matrices. The results suggest that depending upon the polymer matrix used, the application rate of azadirachtin-A can be optimized to achieve insect control at the desired level and period.

  18. The effect of helium generation and irradiation temperature on tritium release from neutron irradiated beryllium

    International Nuclear Information System (INIS)

    Kupriyanov, I.B.; Gorokhov, V.A.; Vlasov, V.V.; Kovalev, A.M.; Chakin, V.P.

    2004-01-01

    The effect of neutron irradiation condition on tritium release from beryllium is described in this paper. Beryllium samples were irradiated in the SM reactor with neutron fluence (E > 0.1 MeV) of (0.37-2.0) x 10 22 cm -2 at 70-100degC and 650-700degC. Mass-spectrometer technique was used in out of tritium release experiments during stepped-temperature anneal within a temperature range from 250 to 1300degC. The total amount of helium accumulated in irradiated beryllium samples varied from 521 appm to 3061 appm. The first signs of tritium release were detected at temperature of 406-553degC. It was shown that irradiation temperature and helium generation level significantly affect the tritium release. A fraction of 44 - 74 % of tritium content in samples irradiated at low temperature (70 - 100degC) is release from beryllium at an annealing temperature below 800degC, whereas for samples after high temperature irradiation (650 - 700 degC) tritium release did not exceed 14 %. Majority of tritium (∼68%) is released within a temperature range from 800 to 920 degC. The increase of helium generation from 521 appm to 3061 appm results in lowering the temperature of maximal tritium release rate and the upper temperature of tritium release from beryllium by 100-130degC and 200-240degC, correspondingly. On the basis of data obtained, the diffusion coefficients of tritium in beryllium were calculated. (author)

  19. Characterizing nuclear and mitochondrial DNA in spent embryo culture media: genetic contamination identified.

    Science.gov (United States)

    Hammond, Elizabeth R; McGillivray, Brent C; Wicker, Sophie M; Peek, John C; Shelling, Andrew N; Stone, Peter; Chamley, Larry W; Cree, Lynsey M

    2017-01-01

    To characterize nuclear and mitochondrial DNA (mtDNA) in spent culture media from normally developing blastocysts to determine whether it could be used for noninvasive genetic assessment. Prospective embryo cohort study. Academic center and private in vitro fertilization (IVF) clinic. Seventy patients undergoing intracytoplasmic sperm injection (ICSI) and 227 blastocysts. Culture media assessment, artificial blastocoele fluid collapse and DNA analysis using digital polymerase chain reaction (dPCR), long-range PCR, quantitative PCR (qPCR), and DNA fingerprinting. Presence of nuclear and mtDNA in three different commercial culture media from Vitrolife and Irvine Scientific, spent embryo media assessment at the cleavage and blastocyst stages of development, and analysis of the internal media controls for each patient that had been exposed to identical conditions as embryo media but did not come into contact with embryos. Higher levels of nuclear and mtDNA were observed in the culture media that had been exposed to embryos compared with the internal media controls. Nuclear DNA (∼4 copies) and mtDNA (∼600 copies) could be detected in spent media, and the levels increased at the blastocyst stage. No increase in DNA was detected after artificial blastocoele fluid collapse. Mixed sex chromosome DNA was detected. This originated from contamination in the culture media and from maternal (cumulus) cells. Due to the limited amount of template, the presence of embryonic nuclear DNA could not be confirmed by DNA fingerprinting analysis. Currently DNA from culture media cannot be used for genetic assessment because embryo-associated structures release DNA into the culture medium and the DNA is of mixed origin. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  20. Release of iodine radionuclides from gas media in a system of selective block sorbents

    International Nuclear Information System (INIS)

    Moskvin, L.N.; Miroshnikov, V.S.; Mel'nikov, V.A.; Chetverikov, V.V.

    1979-01-01

    A scheme of extracting iodine radionuclides from gas flows in a system of selective sorbents has been developed. The method provides separation of three forms of iodine: the aerosol component, the elementary iodine and organic-iodine compounds. Aerosols are trapped by a mechanical filter made of porous polytetrafluoroethylene with pores of no more than 1 μm. Silver-based sorbents for the elementary iodine are made by sintering the granular polytetrafluoroethylene (the size of granules is 0.1-0.5 mm) with of finely dispersed solver (5% mass). Organic iodine compounds are extracted by a silica sorbent impregnated with silver nitrate. The efficiency of sorbents was tested in gas flows with a known content of 131 I in the form of elementary iodine and methyl iodide. The results of experiments show that the efficiency of sorption of elementary iodine by a metallic-silver sorbent and of methyl iodide by a SiO 2 /AgNO 3 sorbent constitutes no less than 99% at a flow rate of up to 200 l/h. The iodine has been extracted at a flow rate of 100 l/h during 100 hours and for that time the efficiency of the iodine sorbtion has not changed. The suggested variant of extracting iodine radionuclides from gaseous media can be used both for fast control of iodine content in gas blowoffs and for researches aimed at studying the distribution of iodine forms in steam-and-gas media depending on nuclear plant operating conditions

  1. InAs migration on released, wrinkled InGaAs membranes used as virtual substrate

    International Nuclear Information System (INIS)

    Filipe Covre da Silva, S; Lanzoni, E M; De Araujo Barboza, V; Deneke, Ch; Malachias, A; Kiravittaya, S

    2014-01-01

    Partly released, relaxed and wrinkled InGaAs membranes are used as virtual substrates for overgrowth with InAs. Such samples exhibit different lattice parameters for the unreleased epitaxial parts, the released flat, back-bond areas and the released wrinkled areas. A large InAs migration towards the released membrane is observed with a material accumulation on top of the freestanding wrinkles during overgrowth. A semi-quantitative analysis of the misfit strain shows that the material migrates to the areas of the sample with the lowest misfit strain, which we consider as the areas of the lowest chemical potential of the surface. Material migration is also observed for the edge-supported, freestanding InGaAs membranes found on these samples. Our results show that the released, wrinkled nanomembranes offer a growth template for InAs deposition that fundamentally changes the migration behavior of the deposited material on the growth surface. (paper)

  2. Sensitive Media

    Directory of Open Access Journals (Sweden)

    Malinowska Anna

    2017-12-01

    Full Text Available The paper engages with what we refer to as “sensitive media,” a concept associated with developments in the overall media environment, our relationships with media devices, and the quality of the media themselves. Those developments point to the increasing emotionality of the media world and its infrastructures. Mapping the trajectories of technological development and impact that the newer media exert on human condition, our analysis touches upon various forms of emergent affect, emotion, and feeling in order to trace the histories and motivations of the sensitization of “the media things” as well as the redefinition of our affective and emotional experiences through technologies that themselves “feel.”

  3. QSPR study of the retention/release property of odorant molecules in pectin gels using statistical methods

    Directory of Open Access Journals (Sweden)

    Assia Belhassan

    2017-11-01

    Full Text Available The ACD/ChemSketch, MarvinSketch, and ChemOffice programmes were used to calculate several molecular descriptors of 51 odorant molecules (15 alcohols, 11 aldehydes, 9 ketones and 16 esters. The best descriptors were selected to establish the Quantitative Structure-Property Relationship (QSPR of the retention/release property of odorant molecules in pectin gels using Principal Components Analysis (PCA, Multiple Linear Regression (MLR, Multiple Non-linear Regression (MNLR and Artificial Neural Network (ANN methods We propose a quantitative model based on these analyses. PCA has been used to select descriptors that exhibit high correlation with the retention/release property. The MLR method yielded correlation coefficients of 0.960 and 0.958 for PG-0.4 (pectin concentration: 0.4% w/w and PG-0.8 (pectin concentration: 0.8% w/w media, respectively. Internal and external validations were used to determine the statistical quality of the QSPR of the two MLR models. The MNLR method, considering the relevant descriptors obtained from the MLR, yielded correlation coefficients of 0.978 and 0.975 for PG-0.4 and PG-0.8 media, respectively. The applicability domain of MLR models was investigated using simple and leverage approaches to detect outliers and outside compounds. The effects of different descriptors on the retention/release property are described, and these descriptors were used to study and design new compounds with higher and lower values of the property than the existing ones. Keywords: Odorant Molecules, Retention/Release, Pectin Gels, Quantitative Structure Property Relationship, Multiple Linear Regression, Artificial Neural Network

  4. Social Media Sites

    Science.gov (United States)

    Media Sites Site Registration Contact Us Search AF.mil: Home > AF Sites > Social Media Sites Social Media Welcome to the Air Force social media directory! The directory is a one-stop shop of official Air Force social media pages across various social media sites. Social media is all about

  5. The Effect of Social Media Usage on Course Achievement and Behavior

    Science.gov (United States)

    Alghazo, Yazan M.; Nash, Julie A.

    2017-01-01

    This study investigated the effects of social media usage as a classroom management tool on students' achievement and their behavior in class. Groups were determined by choosing random samples of different classes. The treatment group included the social media application "whatsapp" which all students and the instructor were asked to…

  6. Media exposure and parental mediation on fast-food consumption among children in metropolitan and suburban Indonesian.

    Science.gov (United States)

    Lwin, May O; Malik, Shelly; Ridwan, Hardinsyah; Au, Cyndy Sook Sum

    2017-01-01

    Fast-food companies have been reproached for rising obesity levels due to aggressive marketing tactics targeted at children. They have countered that parents should be held responsible considering their critical role as nutritional gatekeepers. This study examined the comparative effects of media exposure and parental mediation on Indonesian children's fast food consumption and how the effects compare in the metropolitan versus suburban areas. The sample consisted of 394 child-mother pairs comprising grade three and four children and their mothers from two schools each in Jakarta and Bogor representing 40.9% metropolitan sample and 59.1% suburban sample, respectively. The children completed a guided inclass survey, while the mothers completed a paper-and-pen survey at home. Measures comprised children's weekly media exposure to broadcast media, computer and mobile games, print media, and online and social media, active and restrictive parental mediation strategies, children's fast food consumption and nutrition knowledge. The relationship of media exposure and parental mediation with children's fast food consumption was analyzed using Structural Equation Modelling. Fast food consumption was positively influenced by exposure to broadcast media among metropolitan children, and by exposure to online and social media among suburban children. Active parental mediation was related to lower fast food consumption, but only for suburban children. Active parental mediation is critical in preventing fast food consumption. The media play a key role in influencing fast food consumption, and hence, literacy education is important to alleviate the adverse effects of exposure to junk food marketing.

  7. Stereotypes in media and media literacy among young people

    Directory of Open Access Journals (Sweden)

    Đerić Ivana

    2006-01-01

    Full Text Available Young people, the most common consumers of media content, bear out the view that media shapes people’s lives. Therefore we must not underestimate the effect media exerts on young people’s values and behavioral patterns. Television is the medium which draws children and young people for the greatest part of their free time. Regardless whether television programs are described as positive or negative, whether they abound with stereotypes or not, it is important that young people develop a critical attitude towards them so that they may resist different forms of media manipulation. The paper discusses how stereotypes are generated and used by media and the manners in which stereotypical concepts affect young people’s attitudes. It highlights the importance of the development of media literacy which implies a critical attitude towards media images and discourses, the development of criteria for the selection and evaluation of information broadcast by media, the development of skills in interpreting and understanding stereotypical concepts and familiarity with alternative forms of media culture. The paper draws special attention to the issue of media education. The conclusion is that schools should offer media literacy as part of their curriculum and in it possible solutions to the problems discussed. .

  8. How Are Scientists Using Social Media in the Workplace?

    Directory of Open Access Journals (Sweden)

    Kimberley Collins

    Full Text Available Social media has created networked communication channels that facilitate interactions and allow information to proliferate within professional academic communities as well as in informal social circumstances. A significant contemporary discussion in the field of science communication is how scientists are using (or might use social media to communicate their research. This includes the role of social media in facilitating the exchange of knowledge internally within and among scientific communities, as well as externally for outreach to engage the public. This study investigates how a surveyed sample of 587 scientists from a variety of academic disciplines, but predominantly the academic life sciences, use social media to communicate internally and externally. Our results demonstrate that while social media usage has yet to be widely adopted, scientists in a variety of disciplines use these platforms to exchange scientific knowledge, generally via either Twitter, Facebook, LinkedIn, or blogs. Despite the low frequency of use, our work evidences that scientists perceive numerous potential advantages to using social media in the workplace. Our data provides a baseline from which to assess future trends in social media use within the science academy.

  9. How Are Scientists Using Social Media in the Workplace?

    Science.gov (United States)

    Collins, Kimberley; Shiffman, David; Rock, Jenny

    2016-01-01

    Social media has created networked communication channels that facilitate interactions and allow information to proliferate within professional academic communities as well as in informal social circumstances. A significant contemporary discussion in the field of science communication is how scientists are using (or might use) social media to communicate their research. This includes the role of social media in facilitating the exchange of knowledge internally within and among scientific communities, as well as externally for outreach to engage the public. This study investigates how a surveyed sample of 587 scientists from a variety of academic disciplines, but predominantly the academic life sciences, use social media to communicate internally and externally. Our results demonstrate that while social media usage has yet to be widely adopted, scientists in a variety of disciplines use these platforms to exchange scientific knowledge, generally via either Twitter, Facebook, LinkedIn, or blogs. Despite the low frequency of use, our work evidences that scientists perceive numerous potential advantages to using social media in the workplace. Our data provides a baseline from which to assess future trends in social media use within the science academy.

  10. Princess Elisabeth Antarctica: an International Polar Year outreach and media success story

    Directory of Open Access Journals (Sweden)

    Joseph Cheek

    2011-12-01

    Full Text Available One of the priorities of the fourth International Polar Year (IPY was to increase awareness of the polar regions and polar science among the general public through education, communication and other forms of outreach. This paper reports on the media coverage of Princess Elisabeth Antarctica (PEA, Belgium's “zero-emission” Antarctic research station designed by the non-profit International Polar Foundation (IPF to run on wind and solar energy and to employ state-of-the-art forms of energy management and other “green” technology. This paper provides background information on PEA, a review of IPF's media strategy for the project, a description of media coverage of the station and a discussion of the way in which the IPF's main messages were reported in the media. IPF staff surveyed approximately 300 media reports released between February 2004, when the PEA project was announced to the general public, and June 2010, when the IPF presented their findings at the IPY conference in Oslo. PEA was featured 580 times in print and web media in Belgium, and 303 times outside Belgium. Major international agencies such as the Associated Press, Agence France Presse, the BBC, Al-Jazeera and Reuters covered the project. On television and radio, PEA was featured in news broadcasts from all four major television networks in Belgium, most major radio stations and 34 different television and radio news outlets outside Belgium. The paper concludes that the media coverage for PEA was significant and suggests reasons why the project was so widely reported.

  11. Libraries Protecting Privacy on Social Media: Sharing without "Oversharing"

    Directory of Open Access Journals (Sweden)

    Kelley Cotter

    2016-11-01

    Full Text Available Libraries have increasingly adopted social media as an integral means of connecting with their users. However, social media presents many potential concerns regarding library patron privacy. This article presents the findings from a study of how librarians and library staff perceive and handle issues of patron privacy related to social media marketing in libraries. The study reports the results from a mixed-methods online survey, which used a nonprobability self-selection sampling method to collect responses from individuals employed by libraries, without restrictions on position or library type. Nearly three-quarters of respondents reported working in libraries that have either an official or unofficial social media policy. Approximately 53% of those policies mention patron privacy. The findings suggest that many respondents’ views and practices are influenced by the perception of the library’s physical space and social media presence as public places. The findings also suggest a lack of consensus regarding the extent of the library’s obligation to protect patron privacy on library social media sites and what would constitute a violation of privacy.

  12. Cryo-STEM-EDX spectroscopy for the characterisation of nanoparticles in cell culture media

    Science.gov (United States)

    Ilett, M.; Bamiduro, F.; Matar, O.; Brown, A.; Brydson, R.; Hondow, N.

    2017-09-01

    We present a study of barium titanate nanoparticles dispersed in cell culture media. Scanning transmission electron microscopy combined with energy dispersive X-ray spectroscopy was undertaken on samples prepared using both conventional drop casting and also plunge freezing and examination under cryogenic conditions. This showed that drying artefacts occurred during conventional sample preparation, whereby some salt components of the cell culture media accumulated around the barium titanate nanoparticles; these were removed using the cryogenic route. Importantly, the formation of a calcium and phosphorus rich coating around the barium titanate nanoparticles was retained under cryo-conditions, highlighting that significant interactions do occur between nanomaterials and biological media.

  13. MEDIA SOSIAL DAN PENGEMBANGAN HUBUNGAN INTERPERSONAL REMAJA DI SIDOARJO

    OpenAIRE

    Abadi, Totok Wahyu; Sukmawan, Fandrian; Utari, Dian Asha

    2016-01-01

    The purpose of this study is to analyze and explain the use of social media among teenagers, the development of interpersonal relationships, and the influence of social media on the development of adolescent interpersonal relationships in Sidoarjo. This research, which involves a hundred high school students as the respondents, uses explanative approach. Through random sampling of data collection, the data were analyzed using descriptive statistics analyzing techniques and multiple regression...

  14. Role of calcium in gonadotropin releasing hormone-induced luteinizing hormone secretion from the bovine pituitary

    International Nuclear Information System (INIS)

    Kile, J.P.

    1986-01-01

    The hypothesis was tested that GnRH acts to release LH by increasing calcium uptake by gonadotroph which in turn stimulates calcium-calmodulin activity and results in LH release from bovine pituitary cells as it does in the rat. Pituitary glands of calves (4-10 months of age) were enzymatically dispersed (0.2% collagenase) and grown for 5 days to confluency in multiwell plates (3 x 10 5 /well). Cells treated with GnRH Ca ++ ionophore A23187, and ouabain all produced significant releases of LH release in a pronounced all or none fashion, while thorough washing of the cells with 0.5 mM EGTA in Ca ++ -free media prevented the action of GnRH. GnRH caused a rapid efflux of 45 Ca ++ . Both GnRH-stimulated 45 Ca efflux and LH release could be partially blocked by verapamil GnRH-induced LH release could also be blocked by nifedipine and tetrodotoxin, although these agents did not affect 45 Ca efflux. The calmodulin antagonists calmidazolium and W7 were found to block GnRH induced LH release, as well as LH release induced by theophylline, KC PGE 2 and estradiol. These data indicated that: (1) calcium is required for GnRH action, but extracellular Ca ++ does not regulate LH release; (2) GnRH elevates intracellular Ca ++ by opening both voltage sensitive and receptor mediated Ca ++ channels; (3) activation of calmodulin is one mechanism involved in GnRH-induced LH release

  15. Is News Media Related to Civic Engagement? The Effects of Interest in and Discussions about the News Media on Current and Future Civic Engagement of Adolescents

    Science.gov (United States)

    Erentaite, Rasa; Zukauskiene, Rita; Beyers, Wim; Pilkauskaite-Valickiene, Rasa

    2012-01-01

    This study explored whether discussions about the media, when positively linked to interest in the news media, were related to adolescents' current and future civic engagement. A sample of 2638 adolescents (age M = 17, SD = 1.2), who participated in a school-based study on positive socialization, completed self-report measures on interest in the…

  16. Vapor and gas sampling of single-shell tank 241-U-104 using the in situ vapor sampling system

    International Nuclear Information System (INIS)

    Lockrem, L.L.

    1997-01-01

    The Vapor Issue.Resolution Program tasked the Vapor Team (VT) to collect representative headspace samples from Hanford Site single-shell tank (SST) 241-U-104. This document presents In Situ Vapor Sampling System (ISVS) data resulting from the July 16, 1996 sampling of SST 241-U-104. Analytical results will be presented in separate reports issued by the Pacific Northwest National Laboratory (PNNL) which supplied and analyzed the sample media

  17. Vapor and gas sampling of single-shell tank 241-S-103 using the in situ vapor sampling system

    International Nuclear Information System (INIS)

    Lockrem, L.L.

    1997-01-01

    The Vapor Issue Resolution Program tasked the Vapor Team (VT) to collect representative headspace samples from Hanford Site single-shell tank (SST) 241-S-103. This document presents In Situ Vapor Sampling System (ISVS) data resulting from the June 12, 1996 sampling of SST 241-S-103. Analytical results will be presented in separate reports issued by the Pacific Northwest National Laboratory (PNNL) which supplied and analyzed the sample media

  18. Vapor and gas sampling of single-shell tank 241-S-106 using the in situ vapor sampling system

    International Nuclear Information System (INIS)

    Lockrem, L.L.

    1997-01-01

    The Vapor Issue Resolution Program tasked the Vapor Team (VT) to collect representative headspace samples from Hanford Site single-shell tank (SST) 241-S-106. This document presents In Situ vapor Sampling System (ISVS) data resulting from the June 13, 1996 sampling of SST 241-S-106. Analytical results will be presented in separate reports issued by the Pacific Northwest National Laboratory (PNNL) which'supplied and analyzed the sample media

  19. Evaluation of Slow Release Fertilizer Applying Chemical and Spectroscopic methods

    International Nuclear Information System (INIS)

    AbdEl-Kader, A.A.; Al-Ashkar, E.A.

    2005-01-01

    Controlled-release fertilizer offers a number of advantages in relation to crop production in newly reclaimed soils. Butadiene styrene latex emulsion is one of the promising polymer for different purposes. In this work, laboratory evaluation of butadiene styrene latex emulsion 24/76 polymer loaded with a mixed fertilizer was carried out. Macro nutrients (N, P and K) and micro-nutrients(Zn, Fe, and Cu) were extracted by basic extract from the polymer fertilizer mixtures. Micro-sampling technique was investigated and applied to measure Zn, Fe, and Cu using flame atomic absorption spectrometry in order to overcome the nebulization difficulties due to high salt content samples. The cumulative releases of macro and micro-nutrients have been assessed. From the obtained results, it is clear that the release depends on both nutrients and polymer concentration in the mixture. Macro-nutrients are released more efficient than micro-nutrients of total added. Therefore it can be used for minimizing micro-nutrients hazard in soils

  20. Controlled antiseptic release by alginate polymer films and beads.

    Science.gov (United States)

    Liakos, Ioannis; Rizzello, Loris; Bayer, Ilker S; Pompa, Pier Paolo; Cingolani, Roberto; Athanassiou, Athanassia

    2013-01-30

    Biodegradable polymeric materials based on blending aqueous dispersions of natural polymer sodium alginate (NaAlg) and povidone iodine (PVPI) complex, which allow controlled antiseptic release, are presented. The developed materials are either free standing NaAlg films or Ca(2+)-cross-linked alginate beads, which properly combined with PVPI demonstrate antibacterial and antifungal activity, suitable for therapeutic applications, such as wound dressing. Glycerol was used as the plasticizing agent. Film morphology was studied by optical and atomic force microscopy. It was found that PVPI complex forms well dispersed circular micro-domains within the NaAlg matrix. The beads were fabricated by drop-wise immersion of NaAlg/PVPI/glycerol solutions into aqueous calcium chloride solutions to form calcium alginate beads encapsulating PVPI solution (CaAlg/PVPI). Controlled release of PVPI was possible when the composite films and beads were brought into direct contact with water or with moist media. Bactericidal and fungicidal properties of the materials were tested against Escherichia coli bacteria and Candida albicans fungi. The results indicated very efficient antibacterial and antifungal activity within 48 h. Controlled release of PVPI into open wounds is highly desired in clinical applications to avoid toxic doses of iodine absorption by the wound. A wide variety of applications are envisioned such as external and internal wound dressings with controlled antiseptic release, hygienic and protective packaging films for medical devices, and polymer beads as water disinfectants. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Environmental radiological surveillance in perspective: the relative importance of environmental media as a function of effluent pathway and radionuclides

    International Nuclear Information System (INIS)

    Denham, D.H.

    1977-10-01

    Most published guidelines for environmental surveillance emphasize the collection and analysis of specific media (e.g. air, water, milk, direct radiation) without total regard for the potential dose impact of the radionuclides expected in or actually present in the effluent streams from nuclear facilities. To determine the relative importance of medium/nuclide combinations in environmental surveillance, the experience at major ERDA sites and at operating nuclear power plants was reviewed. Typical release rates for nuclide groupings (tritium, noble gases, radioiodine, mixed fission or activation products, and transuranics) in those effluent streams were followed through various environmental pathways. By using this scheme the environmental medium which is most prominent in the critical dose pathway to man was determined. It was also possible to determine points of short-or long-term contaminant accumulation. Following these calculations, each medium was ranked for a given nuclide/effluent pathway combination providing the relative importance of sampling specific environmental media with emphasis on the radiation dose to a critical population group. Finally, the results of these environmental pathway studies are presented in tabular form to provide ready reference for environmental surveillance program design or evaluation

  2. Effective Social Media Engagement for Nonprofits: What Matters?

    Directory of Open Access Journals (Sweden)

    Julia L Carboni

    2015-03-01

    Full Text Available We employ public management relationship theory to examine how nonprofits can effectively engage social media stakeholders in two-way communication. Though many nonprofit organizations have a social media presence, there is variance in how well organizations use social media to engage stakeholders. Simply having a social media presence is not enough to engage stakeholders.  We examine Facebook posts of a stratified random sample of youth development organizations to determine what predicts stakeholder engagement. We find the type of Facebook post is a significant predictor of stakeholder engagement.  Longer posts also significantly predict increased stakeholder engagement.  At the organizational level, having many posts is a significant negative predictor of stakeholder engagement, indicating that users may feel bombarded and are less likely to engage.  Increased organizational spending on advertising as a proportion of total budget is positively associated with stakeholder engagement. 

  3. PFAS methods and guidance for sampling and analyzing water and other environmental media (Technical Brief)

    Science.gov (United States)

    EPA's methods for analyzing PFAS in environmental media are in various stages of development. This fact sheet summarizes EPA's analytical methods development for groundwater, surface water, wastewater, and solids, including soils, sediments, and biosolids

  4. Media literacy between primary and secondary students in Andalusia (Spain

    Directory of Open Access Journals (Sweden)

    Ignacio Aguaded

    2015-03-01

    Full Text Available The media consumption by children and young people in our society is a fact. Since 2010 there has been an R&D project that aims to assess media literacy in compulsory education in Andalusia. The content was defined in terms of six dimensions developed to assess the skill levels of citizenship. This article analyzes the degree of media literacy in primary and secondary school population in Andalusia. It is an important challenge for the information society to prepare media literate students. The study reports the comparative results of two surveys conducted in a varied sample of Andalusian schools. Both tools are designed to be implemented online with real-time tracking of the platform, to identify needs and gaps and plan for future strategies at school. The study defines media literacy and analysis of its dimensions and various categories of the quantitative study. This research concludes that the population of primary and secondary media literacy lacks the dimensions analyzed. It is, therefore, necessary to develop a course in media education in the school curriculum.

  5. Tritium adsorption/release behaviour of advanced EU breeder pebbles

    Energy Technology Data Exchange (ETDEWEB)

    Kolb, Matthias H.H., E-mail: matthias.kolb@kit.edu; Rolli, Rolf; Knitter, Regina

    2017-06-15

    The tritium loading of current grades of advanced ceramic breeder pebbles with three different lithium orthosilicate (LOS)/lithium metatitanate (LMT) compositions (20–30 mol% LMT in LOS) and pebbles of EU reference material, was performed in a consistent way. The temperature dependent release of the introduced tritium was subsequently investigated by temperature programmed desorption (TPD) experiments to gain insight into the desorption characteristics. The obtained TPD data was decomposed into individual release mechanisms according to well-established desorption kinetics. The analysis showed that the pebble composition of the tested samples does not severely change the release behaviour. Yet, an increased content of lithium metatitanate leads to additional desorption peaks at medium temperatures. The majority of tritium is released by high temperature release mechanisms of chemisorbed tritium, while the release of physisorbed tritium is marginal in comparison. The results allow valuable projections for the tritium release behaviour in a fusion blanket.

  6. Evaluation of hydrophobic materials as matrices for controlled-release drug delivery.

    Science.gov (United States)

    Quadir, Mohiuddin Abdul; Rahman, M Sharifur; Karim, M Ziaul; Akter, Sanjida; Awkat, M Talat Bin; Reza, Md Selim

    2003-07-01

    The present study was undertaken to evaluate the effect of different insoluble and erodable wax-lipid based materials and their content level on the release profile of drug from matrix systems. Matrix tablets of theophylline were prepared using carnauba wax, bees wax, stearic acid, cetyl alcohol, cetostearyl alcohol and glyceryl monostearate as rate-retarding agents by direct compression process. The release of theophylline from these hydrophobic matrices was studied over 8-hours in buffer media of pH 6.8. Statistically significant difference was found among the drug release profile from different matrices. The release kinetics was found to be governed by the type and content of hydrophobic materials in the matrix. At lower level of wax matrices (25%), a potential burst release was observed with all the materials being studied. Bees wax could not exert any sustaining action while an extensive burst release was found with carnauba wax at this hydrophobic load. Increasing the concentration of fat-wax materials significantly decreased the burst effect of drug from the matrix. At higher hydrophobic level (50% of the matrix), the rate and extent of drug release was significantly reduced due to increased tortuosity and reduced porosity of the matrix. Cetostearyl alcohol imparted the strongest retardation of drug release irrespective of fat-wax level. Numerical fits indicate that the Higuchi square root of time model was the most appropriate one for describing the release profile of theophylline from hydrophobic matrices. The release mechanism was also explored and explained with biexponential equation. Application of this model indicates that Fickian or case I kinetics is the predominant mechanism of drug release from these wax-lipid matrices. The mean dissolution time (MDT) was calculated for all the formulations and the highest MDT value was obtained with cetostearyl matrix. The greater sustaining activity of cetostearyl alcohol can be attributed to some level of

  7. Media evolution and ‘epi-technic’ digital media: Media as cultural selection mechanisms

    DEFF Research Database (Denmark)

    Olesen, Mogens

    2016-01-01

    The explosive development of new digital media technologies is often described as a media evolution but hardly ever is the concept of ‘media evolution’ taken at face value. This article takes up that challenge by combining cultural evolution theories with medium theory. The article argues that bi...

  8. Gassmann Theory Applies to Nanoporous Media

    Science.gov (United States)

    Gor, Gennady Y.; Gurevich, Boris

    2018-01-01

    Recent progress in extraction of unconventional hydrocarbon resources has ignited the interest in the studies of nanoporous media. Since many thermodynamic and mechanical properties of nanoscale solids and fluids differ from the analogous bulk materials, it is not obvious whether wave propagation in nanoporous media can be described using the same framework as in macroporous media. Here we test the validity of Gassmann equation using two published sets of ultrasonic measurements for a model nanoporous medium, Vycor glass, saturated with two different fluids, argon, and n-hexane. Predictions of the Gassmann theory depend on the bulk and shear moduli of the dry samples, which are known from ultrasonic measurements and the bulk moduli of the solid and fluid constituents. The solid bulk modulus can be estimated from adsorption-induced deformation or from elastic effective medium theory. The fluid modulus can be calculated according to the Tait-Murnaghan equation at the solvation pressure in the pore. Substitution of these parameters into the Gassmann equation provides predictions consistent with measured data. Our findings set up a theoretical framework for investigation of fluid-saturated nanoporous media using ultrasonic elastic wave propagation.

  9. Social media use and anxiety in emerging adults.

    Science.gov (United States)

    Vannucci, Anna; Flannery, Kaitlin M; Ohannessian, Christine McCauley

    2017-01-01

    Social media use is central to the lives of emerging adults, but the implications of social media use on psychological adjustment are not well understood. The current study aimed to examine the impact of time spent using social media on anxiety symptoms and severity in emerging adults. Using a web-based recruitment technique, we collected survey information on social media use and anxiety symptoms and related impairment in a nationally representative sample of 563 emerging adults from the U.S. (18-22 years-old; 50.2% female; 63.3% Non-Hispanic White). Participants self-reported the amount of time they spent using various social media sites on an average day, and responded to anxiety questionnaires RESULTS: Hierarchical regression revealed that more time spent using social media was significantly associated with greater symptoms of dispositional anxiety (B=0.74, 95% CI=0.59-0.90, psocial media use was significantly associated with a greater likelihood of participants scoring above the anxiety severity clinical cut-off indicating a probable anxiety disorder (AOR=1.032, 95% CI=1.004-1.062, p=0.028). Study limitations include the cross-sectional design and reliance on self-report questionnaires. Given the ubiquity of social media among emerging adults, who are also at high risk for anxiety disorders, the positive association between social media use and anxiety has important implications for clinicians. Gaining a more nuanced understanding of this relationship will help to inform novel approaches to anxiety treatment. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. EFEKTIFITAS PENGGUNAAN MEDIA PETA KONSEP UNTUK MENINGKATKAN PRESTASI BELAJAR AKUNTANSI

    Directory of Open Access Journals (Sweden)

    Agus Wahyudin

    2007-06-01

    Full Text Available the objective of this study is to know the effectiveness of using concept map media to improve the success of learning accounting with the sub-topic is Classification of Account for  XI students 1st semester in SMA Negeri 3 Pekalongan year 2005/2006. Population of the research was all XI students semester 1 SMA Negeri 3 Pekalongan year 2005/2006 with the numbers were 232 students divided into 6 classes. Sample was determined by simple random sampling technique, thus getting 2 classes as the samples, Class XI  IPS 1 consisted of 39 students as the controlled class and class XI IPS 2 consisted of 37 students as the experimental class.  Data was collected by documentation and experimental technique. And the instrument of collecting data was test. In this research, there are 2 data analysis. Those are pre data analysis to equalize the controlled and experimental groups by using normality test, equality test two variance and equality test two average, and the post step analysis to test hypothesis by t-test one right side. The result of t-test showed that the average of learning achievement of experimental group was better than controlled group. It can be concluded that the using of concept map as learning media sub-topic on classification account is more effective than the group without concept map media. From the result of study above, it is suggested that teachers and students can try to use concept map media in the process of accounting learning. Key words: Effectiveness, concept map media and achievement

  11. Prepare to Engage: Building Relationships through Social Media Is a Smart Investment for Institutions

    Science.gov (United States)

    Doak, Jennifer

    2011-01-01

    The people an educational institution is trying to reach--prospective and current students, alumni and parents, to name a few--are no longer passive recipients of press releases and newsletters. They are on Facebook, Twitter, LinkedIn, Google+, and any other social media platform that comes to mind. What can sometimes get lost amid the constant…

  12. #consumingitall: Understanding The Complex Relationship Between Media Consumption And Eating Behaviors

    OpenAIRE

    Albert, Stephanie L.

    2017-01-01

    Adolescents spend almost nine hours a day engaging with media. As a result, they are confronted with large amounts of obesogenic content that shapes their understanding of what are normal and acceptable eating behaviors. Utilizing primary data collected from a sample of 4,838 low-income, racially and ethnically diverse middle school students in Los Angeles County, I studied the effects of different types of media use (i.e., social media, TV/movies/videos, gaming, music, Internet) on dietary p...

  13. Human embryos secrete microRNAs into culture media--a potential biomarker for implantation.

    Science.gov (United States)

    Rosenbluth, Evan M; Shelton, Dawne N; Wells, Lindsay M; Sparks, Amy E T; Van Voorhis, Bradley J

    2014-05-01

    To determine whether human blastocysts secrete microRNA (miRNAs) into culture media and whether these reflect embryonic ploidy status and can predict in vitro fertilization (IVF) outcomes. Experimental study of human embryos and IVF culture media. Academic IVF program. 91 donated, cryopreserved embryos that developed into 28 tested blastocysts, from 13 couples who had previously completed IVF cycles. None. Relative miRNA expression in IVF culture media. Blastocysts were assessed by chromosomal comparative genomic hybridization analysis, and the culture media from 55 single-embryo transfer cycles was tested for miRNA expression using an array-based quantitative real-time polymerase chain reaction analysis. The expression of the identified miRNA was correlated with pregnancy outcomes. Ten miRNA were identified in the culture media; two were specific to spent media (miR-191 and miR-372), and one was only present in media before the embryos had been cultured (miR-645). MicroRNA-191 was more highly concentrated in media from aneuploid embryos, and miR-191, miR-372, and miR-645 were more highly concentrated in media from failed IVF/non-intracytoplasmic sperm injection cycles. Additionally, miRNA were found to be more highly concentrated in ICSI and day-5 media samples when compared with regularly inseminated and day-4 samples, respectively. MicroRNA can be detected in IVF culture media. Some of these miRNA are differentially expressed according to the fertilization method, chromosomal status, and pregnancy outcome, which makes them potential biomarkers for predicting IVF success. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  14. [Validation of the Otitis Media-6 Questionnaire for European Portuguese].

    Science.gov (United States)

    Lameiras, Ana Rita; Silva, Deodato; O'Neill, Assunção; Escada, Pedro

    2017-05-31

    Otitis media is one of the most prevalent childhood diseases. The impact of otitis media on quality of life of Portuguese children is unknown, because of the unavailability of a tool validated in European Portuguese to assess this consequence of otitis media. The Otitis Media-6 questionnaire (Otitis Media-6) is the most frequently used tool to assess health-related quality of life in children with otitis media. This study aims to create a version in the Portuguese language and culturally adapted to Portugal of the otitis media-6 questionnaire. The Otitis Media-6 questionnaire was translated and culturally adapted to the Portuguese language and population. Then, to assess the instrument psychometric properties, it was applied to a sample of Portuguese children with chronic otitis media with effusion or recurrent acute otitis media. The Portuguese version of Otitis Media-6 questionnaire demonstrated the following psychometric properties: construct validity for baseline (rs = 0.98) and change scores (rs = 0.97), internal consistency (α = 0.780), test-retest reliability (rs = 0.89) and responsiveness to clinical change (t(59) = 10.104). The simplicity and brevity of application of the instrument make it ideal for use in research and in clinical practice, enabling a more objective assessment of the extension of the otitis media impact in children quality of life and a more targeted therapeutic decision. The Portuguese version of the Otitis Media-6 questionnaire is a valid, reliable and sensitive instrument to evaluate the health-related quality of life in Portuguese children with otitis media.

  15. Releasability of asbestos fibers from weathered roof cement.

    Science.gov (United States)

    Oberta, Andrew F; Poye, Lee; Compton, Steven P

    2018-03-26

    Chrysotile asbestos fibers were added to roofing products, including roof cement, for several decades. The fibers were described as "encapsulated" and therefore incapable of being released, an assertion that is disproved by the study reported herein. Three test panels of roof cement from the original container were exposed to ambient weathering in 2015 and 2016. Two panels were then sampled using the ASTM D5755 microvacuum method. Sampling revealed a light brown sub-layer under the dark brown surface layer, both of which crumbled and became friable during sampling. Analysis of the microvacuum samples with transmission electron microscopy showed that the material on the two panels contained 4,432,000 and 3,320,000 asbestos structures per cm² with nearly all of the structures consisting of fibers less than 5 µm long. Energy dispersive spectrometry determined that none of the fibers reported were coated with asphalt. The presence of free fibers were confirmed by direct examination of the surfaces of the panels and of dust released from handling the panels via scanning electron microscopy. This study confirmed the releasability of uncoated asbestos fibers from dried roof cement that was indicated in two previous studies published in 2007 and 2010. These results suggest that the finding of the 5th Circuit Court in 1997 that uncoated airborne asbestos fibers cannot be released from roof cement, and therefore do not present a potential exposure by inhalation, was erroneous in retrospect. Theexemption of roof cement from regulation under the Occupational Safety and Health Administration Construction Industry Standard for asbestos by the Court should not be relied on by employers of workers who remove weathered asbestos-containing roof cement, and precautions should be taken against exposure to airborne asbestos fibers during this work.

  16. Cytotoxicity and ion release of alloy nanoparticles

    International Nuclear Information System (INIS)

    Hahn, Anne; Fuhlrott, Jutta; Loos, Anneke; Barcikowski, Stephan

    2012-01-01

    It is well-known that nanoparticles could cause toxic effects in cells. Alloy nanoparticles with yet unknown health risk may be released from cardiovascular implants made of Nickel–Titanium or Cobalt–Chromium due to abrasion or production failure. We show the bio-response of human primary endothelial and smooth muscle cells exposed to different concentrations of metal and alloy nanoparticles. Nanoparticles having primary particle sizes in the range of 5–250 nm were generated using laser ablation in three different solutions avoiding artificial chemical additives, and giving access to formulations containing nanoparticles only stabilized by biological ligands. Endothelial cells are found to be more sensitive to nanoparticle exposure than smooth muscle cells. Cobalt and Nickel nanoparticles caused the highest cytotoxicity. In contrast, Titanium, Nickel–Iron, and Nickel–Titanium nanoparticles had almost no influence on cells below a nanoparticle concentration of 10 μM. Nanoparticles in cysteine dissolved almost completely, whereas less ions are released when nanoparticles were stabilized in water or citrate solution. Nanoparticles stabilized by cysteine caused less inhibitory effects on cells suggesting cysteine to form metal complexes with bioactive ions in media.

  17. Synthesis and release of fatty acids by human trophoblast cells in culture

    International Nuclear Information System (INIS)

    Coleman, R.A.; Haynes, E.B.

    1987-01-01

    In order to determine whether placental cells can synthesize and release fatty acids, trophoblast cells from term human placentas were established in monolayer culture. The cells continued to secrete placental lactogen and progesterone and maintained specific activities of critical enzymes of triacylglycerol and phosphatidylcholine biosynthesis for 24 to 72 hr in culture. Fatty acid was rapidly synthesized from [ 14 C]acetate and released by the cells. Palmitoleic, palmitic, and oleic acids were the major fatty acids synthesized from [ 14 C]acetate and released. Small amounts of lauric, myristic, and stearic acids were also identified. [ 14 C]acetate was also incorporated into cellular triacylglycerol, phospholipid, and cholesterol, but radiolabeled free fatty acid did not accumulate intracellularly. In a pulse-chase experiment, cellular glycerolipids were labeled with [1- 14 C]oleate; trophoblast cells then released 14 C-labeled fatty acid into the media as the cellular content of labeled phospholipid and triacylglycerol decreased without intracellular accumulation of free fatty acid. Twenty percent of the 14 C-label lost from cellular glycerolipid could not be recovered as a chloroform-extractable product, suggesting that some of the hydrolyzed fatty acid had been oxidized. These data indicate that cultured placenta trophoblast cells can release fatty acids that have either been synthesized de novo or that have been hydrolyzed from cellular glycerolipids. Trophoblast cells in monolayer culture should provide an excellent model for molecular studies of placental fatty acid metabolism and release

  18. Microbiology of otitis media in Indigenous Australian children: review.

    Science.gov (United States)

    Jervis-Bardy, J; Carney, A S; Duguid, R; Leach, A J

    2017-07-01

    To review research addressing the polymicrobial aetiology of otitis media in Indigenous Australian children in order to identify research gaps and inform best practice in effective prevention strategies and therapeutic interventions. Literature review. Studies of aspirated middle-ear fluid represented a minor component of the literature reviewed. Most studies relied upon specimens from middle-ear discharge or the nasopharynx. Culture-based middle-ear discharge studies have found that non-typeable Haemophilus influenzae and Streptococcus pneumoniae predominate, with Moraxella catarrhalis, Staphylococcus aureus and Streptococcus pyogenes isolated in a lower proportion of samples. Alloiococcus otitidis was detected in a number of studies; however, its role in otitis media pathogenesis remains controversial. Nasopharyngeal colonisation is a risk factor for otitis media in Indigenous infants, and bacterial load of otopathogens in the nasopharynx can predict the ear state of Indigenous children. Most studies have used culture-based methods and specimens from middle-ear discharge or the nasopharynx. Findings from these studies are consistent with international literature, but reliance on culture may incorrectly characterise the microbiology of this condition. Advances in genomic technologies are now providing microbiologists with the ability to analyse the entire mixed bacterial communities ('microbiomes') of samples obtained from Indigenous children with otitis media.

  19. Body Image Concerns in Young Girls: The Role of Peers and Media Prior to Adolescence

    Science.gov (United States)

    Dohnt, Hayley K.; Tiggemann, Marika

    2006-01-01

    Peer and media influences have been identified as important conveyors of socio-cultural ideals in adolescent and preadolescent samples. This study aims to explore peer and media influences in the body image concerns and dieting awareness of younger girls, aged 5-8 years. A sample of 128 girls was recruited from the first 4 years of formal…

  20. Furfural production from biomass pretreatment hydrolysate using vapor-releasing reactor system.

    Science.gov (United States)

    Liu, Lu; Chang, Hou-Min; Jameel, Hasan; Park, Sunkyu

    2018-03-01

    Biomass hydrolysate from autohydrolysis pretreatment was used for furfural production considering it is in rich of xylose, xylo-oligomers, and other decomposition products from hemicellulose structure. By using the vapor-releasing reactor system, furfural was protected from degradation by separating it from the reaction media. The maximum furfural yield of 73% was achieved at 200 °C for biomass hydrolysate without the use of the catalyst. This is because the presence of organic acids such as acetic acid in hydrolysate functioned as a catalyst. According to the results in this study, biomass hydrolysate with a vapor-releasing system proves to be efficient for furfural production. The biorefinery process which allows the separation of xylose-rich autohydrolysate from other parts from biomass feedstock also improves the overall application of the biomass. Copyright © 2018 Elsevier Ltd. All rights reserved.

  1. Ring head recording on perpendicular media: Output spectra for CoCr and CoCr/NiFe media

    Science.gov (United States)

    Stubbs, D. P.; Whisler, J. W.; Moe, C. D.; Skorjanec, J.

    1985-04-01

    The recording density response for sputtered CoCr (thickness=0.5 μm) and CoCr/NiFe (t=0.25 μm/0.5 μm) as well as evaporated CoNi (t=0.12 μm) and Co surface-doped iron oxide particulate media has been measured by reading and writing with Mn-Zn ferrite heads (gap length=0.375 μm, track width=37 μm) in contact with the media. Measurements to 200 kfc/i (thousand flux changes per inch) show a gap null around 115 kfc/i. The data have been normalized by dividing out the head sensitivity to obtain the value of spacing plus transition width (d+a) for the various media. For the CoCr media this value varied from 0.075-0.088 μm; for CoNi, 0.100 μm, and for the particulate medium, 0.163 μm. In addition, testing with a larger gapped Mn-Zn ferrite head (g=2.43 μm) shows that the head fields are distorted by the soft magnetic underlayer in dual layer CoCr/NiFe samples when the gap length is large compared to the distance to the underlayer.

  2. Influence of dissolution media pH and USP1 basket speed on erosion and disintegration characteristics of immediate release metformin hydrochloride tablets.

    Science.gov (United States)

    Desai, Divyakant; Wong, Benjamin; Huang, Yande; Tang, Dan; Hemenway, Jeffrey; Paruchuri, Srinivasa; Guo, Hang; Hsieh, Daniel; Timmins, Peter

    2015-01-01

    To investigate the influence of the pH of the dissolution medium on immediate release 850 mg metformin hydrochloride tablets. A traditional wet granulation method was used to manufacture metformin hydrochloride tablets with or without a disintegrant. Tablet dissolution was conducted using the USP apparatus I at 100 rpm. In spite of its pH-independent high solubility, metformin hydrochloride tablets dissolved significantly slower in 0.1 N HCl (pH 1.2) and 50 mM pH 4.5 acetate buffer compared with 50 mM pH 6.8 phosphate buffer, the dissolution medium in the USP. Metformin hydrochloride API compressed into a round 1200 mg disk showed a similar trend. When basket rotation speed was increased from 100 to 250 rpm, the dissolution of metformin hydrochloride tablets was similar in all three media. Incorporation of 2% w/w crospovidone in the tablet formulation improved the dissolution although the pH-dependent trend was still evident, but incorporation of 2% w/w croscarmellose sodium resulted in rapid pH-independent tablet dissolution. In absence of a disintegrant in the tablet formulation, the dissolution was governed by the erosion-diffusion process. Even for a highly soluble drug, a super-disintegrant was needed in the formulation to overcome the diffusion layer limitation and change the dissolution mechanism from erosion-diffusion to disintegration.

  3. Investigation of tritium release and retention in lithium aluminate

    International Nuclear Information System (INIS)

    Kopasz, J.P.; Tistchenko, S.; Botter, F.

    1991-01-01

    Tritium release from lithium aluminate, although previously investigated by both in-reactor and ex-reactor experiments, remains poorly understood. Agreement between experiments is lacking, and the mechanisms responsible for tritium release from lithium aluminate are under debate. In an effort to improve our understanding of the mechanisms of tritium release from lithium ceramics, we have investigated tritium release from pure lithium aluminate and lithium aluminate doped with impurities. The results of these experiments on large grain size material indicate that after anneals at low temperature, a large fraction of the tritium present before the anneal remains in the sample. We have modeled this behavior based on first-order release from three types of sites. At the lowest temperature, the release is dominated by one site, while the tritium in the other sites is retained in the solid. Adding magnesium dopant to the ceramic appears to alter the distribution of tritium between the sites. This addition decreases the fraction of tritium released at 777 degree C, while increasing the fractions released at 538 and 950 degree C. 11 refs., 8 figs., 1 tab

  4. Study of variance and covariance terms in linear attenuation coefficient measurements of irregular samples through the two media method by gamma-ray transmission

    International Nuclear Information System (INIS)

    Kuramoto, R.Y.R.Renato Yoichi Ribeiro.; Appoloni, Carlos Roberto

    2002-01-01

    The two media method permits the application of Beer's law (Thesis (Master Degree), Universidade Estadual de Londrina, PR, Brazil, pp. 23) for the linear attenuation coefficient determination of irregular thickness samples by gamma-ray transmission. However, the use of this methodology introduces experimental complexity due to the great number of variables to be measured. As consequence of this complexity, the uncertainties associated with each of these variables may be correlated. In this paper, we examine the covariance terms in the uncertainty propagation, and quantify the correlation among the uncertainties of each of the variables in question

  5. Glass sampling program during DWPF Integrated Cold Runs

    International Nuclear Information System (INIS)

    Plodinec, M.J.

    1990-01-01

    The described glass sampling program is designed to achieve two objectives: To demonstrate Defense Waste Processing Facility (DWPF) ability to control and verify the radionuclide release properties of the glass product; To confirm DWPF's readiness to obtain glass samples during production, and SRL's readiness to analyze and test those samples remotely. The DWPF strategy for control of the radionuclide release properties of the glass product, and verification of its acceptability are described in this report. The basic approach of the test program is then defined

  6. Hanford site environmental surveillance master sampling schedule

    International Nuclear Information System (INIS)

    Bisping, L.E.

    1998-01-01

    Environmental surveillance of the Hanford Site and surrounding areas is conducted by the Pacific Northwest National Laboratory (PNNL) for the U.S. Department of Energy (DOE). Sampling is conducted to evaluate levels of radioactive and nonradioactive pollutants in the Hanford environs, as required in DOE Order 5400.1 open-quotes General Environmental Protection Program,close quotes and DOE Order 5400.5, open-quotes Radiation Protection of the Public and the Environment.close quotes The sampling methods are described in the Environmental Monitoring Plan, United States Department of Energy, Richland Operations Office, DOE/RL91-50, Rev. 2, U.S. Department of Energy, Richland, Washington. This document contains the 1998 schedules for routine collection of samples for the Surface Environmental Surveillance Project (SESP) and Drinking Water Monitoring Project. Each section of this document describes the planned sampling schedule for a specific media (air, surface water, biota, soil and vegetation, sediment, and external radiation). Each section includes the sample location, sample type, and analyses to be performed on the sample. In some cases, samples are scheduled on a rotating basis and may not be planned for 1998 in which case the anticipated year for collection is provided. In addition, a map is included for each media showing sample locations

  7. Media education.

    Science.gov (United States)

    Strasburger, Victor C

    2010-11-01

    The American Academy of Pediatrics recognizes that exposure to mass media (eg, television, movies, video and computer games, the Internet, music lyrics and videos, newspapers, magazines, books, advertising) presents health risks for children and adolescents but can provide benefits as well. Media education has the potential to reduce the harmful effects of media and accentuate the positive effects. By understanding and supporting media education, pediatricians can play an important role in reducing harmful effects of media on children and adolescents.

  8. Using Social Media and Targeted Snowball Sampling to Survey a Hard-to-reach Population: A Case Study

    Directory of Open Access Journals (Sweden)

    Gary Dusek

    2015-08-01

    Full Text Available Response rates to the academic surveys used in quantitative research are decreasing and have been for several decades among both individuals and organizations. Given this trend, providing doctoral students an opportunity to complete their dissertations in a timely and cost effective manner may necessitate identifying more innovative and relevant ways to collect data while maintaining appropriate research standards and rigor. The case of a research study is presented which describes the data collection process used to survey a hard-to-reach population. It details the use of social media, in this case LinkedIn, to facilitate the distribution of the web-based survey. A roadmap to illustrate how this data collection process unfolded is presented, as well as several “lessons learned” during this journey. An explanation of the considerations that impacted the sampling design is provided. The goal of this case study is to provide researchers, including doctoral students, with realistic expectations and an awareness of the benefits and risks associated with the use of this method of data collection.

  9. Sexual media exposure, sexual behavior, and sexual violence victimization in adolescence.

    Science.gov (United States)

    Ybarra, Michele L; Strasburger, Victor C; Mitchell, Kimberly J

    2014-11-01

    Emerging research suggests sexual media affects sexual behavior, but most studies are based on regional samples and few include measures of newer mediums. Furthermore, little is known about how sexual media relates to sexual violence victimization. Data are from 1058 youth 14 to 21 years of age in the national, online Growing up with Media study. Forty-seven percent reported that many or almost all/all of at least one type of media they consumed depicted sexual situations. Exposure to sexual media in television and movies, and music was greater than online and in games. All other things equal, more frequent exposure to sexual media was related to ever having had sex, coercive sex victimization, and attempted/completed rape but not risky sexual behavior. Longer standing mediums such as television and movies appear to be associated with greater amounts of sexual media consumption than newer ones, such as the Internet. A nuanced view of how sexual media content may and may not be affecting today's youth is needed. © The Author(s) 2014.

  10. Coping with the media during emergencies

    International Nuclear Information System (INIS)

    Denman, A.R.

    2000-01-01

    Radiation emergencies can quickly attract the attention of the Media. Scientific Experts responding to the emergency can find that they are in the forefront of press attention, distracting them from their main objectives. Whilst the police take a lead in dealing with the Media, experts cannot avoid becoming involved: a consideration when drawing up Response Plants. The Media respond rapidly to a national or international incident, with reporters arriving within minutes, and satellite vans, capable of beaming images across the world, shortly afterwards. When Michel Schumacher was recently admitted to Northampton General Hospital after breaking his leg inn the British Grand Prix, the local press arrived at the hospital before he did, with international press arriving within minutes, and the first satellite van within an hour. UK police now consider it appropriate for a simple statement to be released as soon after the incident as possible, rather than allow rumor to circulate. Although such a statement is agreed before making it, a press conference involving an expert is preferred to cover the more technical questions. The expert will need to try out simple descriptions of the degree of public risk (e.g. equivalent to a couple of Chest X-ray) with the Police Press Office before conference. This can delay the expert's other required actions. Thus when depleted uranium filings were found in a field in Northampton-shire in 1995, the first Press Conference was made outside the site before the waste had been fully assessed. The Media also require visual images. This leads them to enter a restricted site, or over-fly with helicopters. Thus the Emergency Response Team need to consider whether it is necessary to increase police resource to restrict access, or to organize a photo session of the site, with necessary decontamination monitoring afterwards. This latter option was taken in the uranium incident as the police considered it was impossible to limit access to the field

  11. The microbiome of otitis media with effusion.

    Science.gov (United States)

    Chan, Chun Ling; Wabnitz, David; Bardy, Jake Jervis; Bassiouni, Ahmed; Wormald, Peter-John; Vreugde, Sarah; Psaltis, Alkis James

    2016-12-01

    The adenoid pad has been considered a reservoir for bacteria in the pathogenesis of otitis media with effusion. This study aimed to characterize the middle ear microbiota in children with otitis media with effusion and establish whether a correlation exists between the middle ear and adenoid microbiota. Prospective, controlled study. Middle ear aspirates adenoid pad swabs were collected from 23 children undergoing ventilation tube insertion. Adenoid swabs from patients without ear disease were controls. Samples were analyzed using 16S rRNA sequencing on the Illumina MiSeq platform. Thirty-five middle ear samples were collected. The middle ear effusion microbiota was dominated by Alloiococcus otitidis (23% mean relative abundance), Haemophilus (22%), Moraxella (5%), and Streptococcus (5%). Alloiococcus shared an inverse correlation with Haemophilus (P = .049) and was found in greater relative abundance in unilateral effusion (P = .004). The microbiota of bilateral effusions from the same patient were similar (P effusion microbiota were found to be dissimilar to that of the adenoid (P = .01), whereas the adenoid microbiota of otitis media with effusion and control patients were similar (P > .05) (permutational multivariate analysis of the variance). Dissimilarities between the local microbiota of the adenoid and the middle ear question the theory that the adenoid pad is a significant reservoir to the middle ear in children with otitis media with effusion. A otitidis had the greatest cumulative relative abundance, particularly in unilateral effusions, and shares an inverse correlation with the relative abundance of Haemophilus. NA Laryngoscope, 126:2844-2851, 2016. © 2016 The American Laryngological, Rhinological and Otological Society, Inc.

  12. Social network media exposure and adolescent eating pathology in Fiji

    Science.gov (United States)

    Becker, Anne E.; Fay, Kristen E.; Agnew-Blais, Jessica; Khan, A. Nisha; Striegel-Moore, Ruth H.; Gilman, Stephen E.

    2011-01-01

    Background Mass media exposure has been associated with an increased risk of eating pathology. It is unknown whether indirect media exposure – such as the proliferation of media exposure in an individual’s social network – is also associated with eating disorders. Aims To test hypotheses that both individual (direct) and social network (indirect) mass media exposures were associated with eating pathology in Fiji. Method We assessed several kinds of mass media exposure, media influence, cultural orientation and eating pathology by self-report among adolescent female ethnic Fijians (n = 523). We fitted a series of multiple regression models of eating pathology, assessed by the Eating Disorder Examination Questionnaire (EDE–Q), in which mass media exposures, sociodemographic characteristics and body mass index were entered as predictors. Results Both direct and indirect mass media exposures were associated with eating pathology in unadjusted analyses, whereas in adjusted analyses only social network media exposure was associated with eating pathology. This result was similar when eating pathology was operationalised as either a continuous or a categorical dependent variable (e.g. odds ratio OR = 1.60, 95% CI 1.15–2.23 relating social network media exposure to upper-quartile EDE–Q scores). Subsequent analyses pointed to individual media influence as an important explanatory variable in this association. Conclusions Social network media exposure was associated with eating pathology in this Fijian study sample, independent of direct media exposure and other cultural exposures. Findings warrant further investigation of its health impact in other populations. PMID:21200076

  13. Implanted Deuterium Retention and Release in Carbon-Coated Beryllium

    Science.gov (United States)

    Anderl, R. A.; Longhurst, G. R.; Pawelko, R. J.; Oates, M. A.

    1997-06-01

    Deuterium implantation experiments have been conducted on samples of clean and carbon-coated beryllium. These studies entailed preparation and characterization of beryllium samples coated with carbon thicknesses of 100, 500, and 1000 Å. Heat treatment of a beryllium sample coated with carbon to a thickness of approximately 100 Å revealed that exposure to a temperature of 400°C under high vacuum conditions was sufficient to cause substantial diffusion of beryllium through the carbon layer, resulting in more beryllium than carbon at the surface. Comparable concentrations of carbon and beryllium were observed in the bulk of the coating layer. Higher than expected oxygen levels were observed throughout the coating layer as well. Samples were exposed to deuterium implantation followed by thermal desorption without exposure to air. Differences were observed in deuterium retention and postimplantation release behavior in the carbon-coated samples as compared with bare samples. For comparable implantation conditions (sample temperature of 400°C and an incident deuterium flux of approximately 6 × 1019 D/m2-s), the quantity of deuterium retained in the bare sample was less than that retained in the carbon-coated samples. Further, the release of the deuterium took place at lower temperatures for the bare beryllium surfaces than for carbon-coated beryllium samples.

  14. Media Framing

    DEFF Research Database (Denmark)

    Pedersen, Rasmus T.

    2017-01-01

    The concept of media framing refers to the way in which the news media organize and provide meaning to a news story by emphasizing some parts of reality and disregarding other parts. These patterns of emphasis and exclusion in news coverage create frames that can have considerable effects on news...... consumers’ perceptions and attitudes regarding the given issue or event. This entry briefly elaborates on the concept of media framing, presents key types of media frames, and introduces the research on media framing effects....

  15. Conjugation of isoniazid to a zinc phthalocyanine via hydrazone linkage for pH-dependent liposomal controlled release

    Science.gov (United States)

    Nkanga, Christian Isalomboto; Krause, Rui Werner Maçedo

    2018-05-01

    Tuberculosis (TB) remains the leading cause of mortality from infectious diseases. Extended TB treatment and frequent adverse effects, due to poor bioavailability of anti-tubercular drugs (ATBDs), represent the main rationales behind liposomal encapsulation for controlled delivery. Liposomes have been reported as potential vehicles for targeted delivery of ATBDs due to their rapid uptake by macrophages, which are known as the main host cells for TB causative agent (Mycobacterium tuberculosis). Additionally, the need for controlled release of ATBDs arises because leakage is part of the key liposome challenges for hydrophilic compounds like isoniazid (INH). In this study, INH was conjugated to a highly hydrophobic photosensitizer, zinc (II) phthalocyanine (PC), through hydrazone bonding. The obtained conjugate (PC-INH) was encapsulated in liposomes by film hydration method. PC-INH loaded liposomes (PILs) were characterized using dynamic light scattering, transmission electron microscopy, energy-dispersive X-ray spectrometry and UV-Vis absorption spectrometry, which was used also for estimation of encapsulation efficiency (%EE). INH release was evaluated in different pH media using dialysis. Particle size, zeta potential and %EE of PILs were about 506 nm, - 55 mV and 72%, respectively. Over 12 h, PILs exhibited 22, 41, 97 and 100% of INH, respectively, released in pH 7.4, 6.4, 5.4 and 4.4 media. This pH-dependent behavior is attractive for site-specific delivery. These findings suggest the conjugation of chemotherapeutics to phthalocyanines using pH-labile linkages as a potential strategy for liposomal controlled release.

  16. Children's media consumption in Serbia

    Directory of Open Access Journals (Sweden)

    Filipović Jelena

    2009-01-01

    Full Text Available The paper aims at providing an insight into media consumption among children in Serbia. A consumer survey was conducted to examine differences in children's consumption of various advertising media based on their age, gender and hometown. The research findings revealed significant differences between the two age cohorts in the three out of four tested media categories (TV, print, radio and Internet. On the other hand, the research findings also revealed variations in consumption of radio and print media, and no difference in the consumption of television and Internet between boys and girls. Finally, the research findings suggested significant differences in the consumption of Internet among children living in five cities in Serbia. Though the sample included more than 700 children it cannot be considered strictly representative for the whole country since the survey was conducted in urban areas only. However, the greatest value of this study comes from the fact that the research was placed in Serbia as a transitional society of the Western Balkans which has been seriously underrepresented in the main body of contemporary marketing theory and research studies. Therefore, one of the main goals of this paper was to make a contribution to better understanding of local conditions that might influence marketing decisions when communicating with children as a specific target group on Serbian market.

  17. Bilayer tablets of Paliperidone for Extended release osmotic drug delivery

    Science.gov (United States)

    Chowdary, K. Sunil; Napoleon, A. A.

    2017-11-01

    The purpose of this study is to develop and optimize the formulation of paliperidone bilayer tablet core and coating which should meet in vitro performance of trilayered Innovator sample Invega. Optimization of core formulations prepared by different ratio of polyox grades and optimization of coating of (i) sub-coating build-up with hydroxy ethyl cellulose (HEC) and (ii).enteric coating build-up with cellulose acetate (CA). Some important influence factors such as different core tablet compositions and different coating solution ingredients involved in the formulation procedure were investigated. The optimization of formulation and process was conducted by comparing different in vitro release behaviours of Paliperidone. In vitro dissolution studies of Innovator sample (Invega) with formulations of different release rate which ever close release pattern during the whole 24 h test is finalized.

  18. Gas chromatographic-mass spectrometric characterisation of plant gums in samples from painted works of art.

    Science.gov (United States)

    Bonaduce, Ilaria; Brecoulaki, Hariclia; Colombini, Maria Perla; Lluveras, Anna; Restivo, Vincenzo; Ribechini, Erika

    2007-12-21

    This paper presents an analytical GC-MS procedure to study the chemical composition of plant gums, determining aldoses and uronic acids in one step. The procedure is based on the silylation of aldoses and uronic acids, released from plant gums by microwave assisted hydrolysis, and previously converted into the corresponding diethyl-dithioacetals and diethyl-dithioacetal lactones. Using this method only one peak for each compound is obtained, thus providing simple and highly reproducible chromatograms. The analytical procedure was optimised using reference samples of raw plant gums (arabic, karaya, ghatti, guar, locust bean and tragacanth, cherry, plum and peach gums), commercial watercolours and paint layers prepared according to ancient recipes at the Opificio delle Pietre Dure of Florence (Italy). To identify gum media in samples of unknown composition, a decisional schema for the gum identification and the principal component analysis of the relative sugar percentage contents were employed. The procedure was used to study samples collected from wall paintings from Macedonian tombs (4th-3rd centuries bc) and from the Mycenaean "Palace of Nestor" (13th century bc) in Pylos, Greece. The presence of carbohydrates was ascertained and plant gum binders (fruit and a mixture of tragacanth and fruit tree gums) were identified in some of the samples.

  19. Closure report for CAU No. 450: Historical UST release sites, Nevada Test Site. Volume 1

    International Nuclear Information System (INIS)

    1997-09-01

    This report addresses the closure of 11 historical underground storage tank (UST) release sites within various areas of the Nevada Test Site (NTS). The closure of each hydrocarbon release has not been documented, therefore, this report addresses the remedial activities completed for each release site. The hydrocarbon release associated with each tank site within CAU 450 was remediated by excavating the impacted soil. Clean closure of the release was verified through soil sample analysis by an off-site laboratory. All release closure activities were completed following standard environmental and regulatory guidelines. Based upon site observations during the remedial activities and the soil sample analytical results, which indicated that soil concentrations were below the Nevada Administrative code (NAC) Action Level of 100 mg/kg, it is anticipated that each of the release CASs be closed without further action

  20. Influence of Pneumococcal Conjugate Vaccine on Acute Otitis Media with Severe Middle Ear Inflammation: A Retrospective Multicenter Study.

    Science.gov (United States)

    Sugino, Hirotoshi; Tsumura, Shigeru; Kunimoto, Masaru; Noda, Masuhiro; Chikuie, Daisuke; Noda, Chieko; Yamashita, Mariko; Watanabe, Hiroshi; Ishii, Hidemasa; Tashiro, Toru; Iwata, Kazuhiro; Kono, Takashi; Tsumura, Kaoru; Sumiya, Takahiro; Takeno, Sachio; Hirakawa, Katsuhiro

    2015-01-01

    The Japanese guidelines for acute otitis media in children recommend classifying acute otitis media by age, manifestations and local findings, and also recommend myringotomy for moderate-grade cases with severe local findings, severe-grade cases, and treatment-resistant cases. The heptavalent pneumococcal conjugate vaccine was released in Japan in February 2010. In Hiroshima City, public funding allowing free inoculation with this vaccine was initiated from January 2011, and the number of vaccinated individuals has since increased dramatically. This study investigated changes in the number of myringotomies performed to treat acute otitis media during the 5-year period from January 2008 to December 2012 at two hospitals and five clinics in the Asa Area of Hiroshima City, Japan. A total of 3,165 myringotomies for acute otitis media were performed. The rate of procedures per child-year performed in otitis media in 1-year-old infants decreased significantly in the 2 years after the introduction of public funding for heptavalent pneumococcal conjugate vaccine compared to all years before introduction (potitis media in reducing the financial burden of myringotomy. In addition, this vaccine may help prevent acute otitis media with severe middle ear inflammation in 1-year-old infants.

  1. Release Storage and Disposal Program Product Sampling Support

    International Nuclear Information System (INIS)

    CALMUS, R.B.

    2000-01-01

    This document includes recommended capabilities and/or services to support transport, analysis, and disposition of Immobilized High-Level and Low-Activity Waste samples as requested by the US DOE-Office of River Protection (DOE-ORP) as specified in the Privatization Contract between DOE-ORP and BNFL Inc. In addition, an approved implementation path forward is presented which includes use of existing Hanford Site services to provide the required support capabilities

  2. Media Entrepreneurship

    DEFF Research Database (Denmark)

    Khajeheian, Datis

    2017-01-01

    Media Entrepreneurship has been an ambiguous, unclear and controversial concept and despite of growing academic efforts in the last decade, it is still a poorly defined subject. This paper is an effort to fill this gap by providing a comprehensive definition of media entrepreneurship. Firstly......, a literature review conducted and entrepreneurship, media, opportunity and innovation as building blocks of media entrepreneurship explained. Then by using of a mixed of bibliographic method and a Delphi method with multi-stage analysis process, a consensual definition of media entrepreneurship proposed...... entrepreneurship....

  3. Metal release from coffee machines and electric kettles.

    Science.gov (United States)

    Müller, Frederic D; Hackethal, Christin; Schmidt, Roman; Kappenstein, Oliver; Pfaff, Karla; Luch, Andreas

    2015-01-01

    The release of elemental ions from 8 coffee machines and 11 electric kettles into food simulants was investigated. Three different types of coffee machines were tested: portafilter espresso machines, pod machines and capsule machines. All machines were tested subsequently on 3 days before and on 3 days after decalcification. Decalcification of the machines was performed with agents according to procedures as specified in the respective manufacturer's manuals. The electric kettles showed only a low release of the elements analysed. For the coffee machines decreasing concentrations of elements were found from the first to the last sample taken in the course of 1 day. Metal release on consecutive days showed a decreasing trend as well. After decalcification a large increase in the amounts of elements released was encountered. In addition, the different machine types investigated clearly differed in their extent of element release. By far the highest leaching, both quantitatively and qualitatively, was found for the portafilter machines. With these products releases of Pb, Ni, Mn, Cr and Zn were in the range and beyond the release limits as proposed by the Council of Europe. Therefore, a careful rinsing routine, especially after decalcification, is recommended for these machines. The comparably lower extent of release of one particular portafilter machine demonstrates that metal release at levels above the threshold that triggers health concerns are technically avoidable.

  4. New media technologies and mass media reform processes

    Directory of Open Access Journals (Sweden)

    Tomić Boban

    2017-01-01

    Full Text Available This paper reviews and assesses the chances for survival and development of the media in Serbia and ib the region, from the perspective of new information and communication technologies (ICT applied in media business. In the paper theoretical method is used and harmonized with the needs of describing the problems and the observed processes and phenomena, as well as empirical method which is used for collecting and interpreting concrete facts and data on the observed processes and phenomena. The starting point lies in the fact that modern media is definitely, more and more, dependent on new technologies. A part of the new technologies is used in the process of collecting, selecting and editing media content, while the other part of the technology is used in the process of dissemination and propulsion of media content to the mass audience, and also in the feedback function as well. The technology revolution, which we describe, started with mp3, jpg and avi files, and continues with internet broadcasting, social networks, cloud technologies and new digital platforms which are used by today's media for distribution of media content. The particularity of the media in the region lies in the fact that they operating in the societes with delay of political and economic transition, so all the productive resources of society, due to this backlog, are slower adapted to the new conditions of business in the digital era. The consequences that have arisen from such dynamics of development make many media in Serbia and the region quite dysfunctional, especially those who were exposed during this transition to long-standing legal, economic and program crises. That is why most of the existing media in Serbia, especially small ones, are unprepared for modernization and they are not ready for re-modeling in accordance with the new technological circumstances.

  5. Mass Spectrometric Determination of Chemical Warfare Agents in Indoor Sample Media Typically Collected During Forensic Investigations

    National Research Council Canada - National Science Library

    D'Agostino, P. A; Hancock, J. R; Chenier, C. L

    2005-01-01

    .... DRDC Suffield, in collaboration with the Royal Canadian Mounted Police, identified a need for analytical methods for chemical warfare agent identification in media, including flooring, wall surfaces...

  6. Social media use among patients and caregivers: a scoping review.

    Science.gov (United States)

    Hamm, Michele P; Chisholm, Annabritt; Shulhan, Jocelyn; Milne, Andrea; Scott, Shannon D; Given, Lisa M; Hartling, Lisa

    2013-05-09

    To map the state of the existing literature evaluating the use of social media in patient and caregiver populations. Scoping review. Medline, CENTRAL, ERIC, PubMed, CINAHL Plus Full Text, Academic Search Complete, Alt Health Watch, Health Source, Communication and Mass Media Complete, Web of Knowledge and ProQuest (2000-2012). Studies reporting primary research on the use of social media (collaborative projects, blogs/microblogs, content communities, social networking sites, virtual worlds) by patients or caregivers. Two reviewers screened studies for eligibility; one reviewer extracted data from relevant studies and a second performed verification for accuracy and completeness on a 10% sample. Data were analysed to describe which social media tools are being used, by whom, for what purpose and how they are being evaluated. Two hundred eighty-four studies were included. Discussion forums were highly prevalent and constitute 66.6% of the sample. Social networking sites (14.8%) and blogs/microblogs (14.1%) were the next most commonly used tools. The intended purpose of the tool was to facilitate self-care in 77.1% of studies. While there were clusters of studies that focused on similar conditions (eg, lifestyle/weight loss (12.7%), cancer (11.3%)), there were no patterns in the objectives or tools used. A large proportion of the studies were descriptive (42.3%); however, there were also 48 (16.9%) randomised controlled trials (RCTs). Among the RCTs, 35.4% reported statistically significant results favouring the social media intervention being evaluated; however, 72.9% presented positive conclusions regarding the use of social media. There is an extensive body of literature examining the use of social media in patient and caregiver populations. Much of this work is descriptive; however, with such widespread use, evaluations of effectiveness are required. In studies that have examined effectiveness, positive conclusions are often reported, despite non

  7. Interim report: Study of benzene release from Savannah River in-tank precipitation process slurry simulant

    International Nuclear Information System (INIS)

    Rappe, K.G.; Gauglitz, P.A.

    1997-09-01

    At the Savannah River Site, the in-tank precipitation (ITP) process uses sodium tetraphenylborate (NaTPB) to precipitate radioactive cesium from alkaline wastes. During this process, potassium is also precipitated to form a 4-wt% KTPB/CsTPB slurry. Residual NaTPB decomposes to form benzene, which is retained by the waste slurry. The retained benzene is also readily released from the waste during subsequent waste processing. While the release of benzene certainly poses both flammability and toxicological safety concerns, the magnitude of the hazard depends on the rate of release. Currently, the mechanisms controlling the benzene release rates are not well understood, and predictive models for estimating benzene release rates are not available. The overall purpose of this study is to obtain quantitative measurements of benzene release rates from a series of ITP slurry stimulants. This information will become a basis for developing a quantitative mechanistic model of benzene release rates. The transient benzene release rate was measured from the surface of various ITP slurry (solution) samples mixed with benzene. The benzene release rate was determined by continuously purging the headspace of a sealed sample vessel with an inert gas (nitrogen) and analyzing that purged headspace vapor for benzene every 3 minutes. The following 75-mL samples were measured for release rates: KTPB slurry with 15,000 ppm freshly added benzene that was gently mixed with the slurry, KTPB slurry homogenized (energetically mixed) with 15,000 ppm and 5,000 ppm benzene, clear and filtered KTPB salt solution saturated with benzene (with and without a pure benzene layer on top of the solution), and a slurry sample from a large demonstration experiment (DEMO slurry) containing-benzene generated in situ

  8. [Media for 21st century--towards human communication media].

    Science.gov (United States)

    Harashima, H

    2000-05-01

    Today, with the approach of the 21st century, attention is focused on multi-media communications combining computer, visual and audio technologies. This article discusses the communication media target and the technological problems constituting the nucleus of multi-media. The communication media is becoming an environment from which no one can escape. Since the media has such a great power, what is needed now is not to predict the future technologies, but to estimate the future world and take to responsibility for future environments.

  9. Consumers’ social media brand behaviors: uncovering underlying motivators and deriving meaningful consumer segments

    OpenAIRE

    Dimitriu, Radu; Guesalaga Trautmann, Rodrigo

    2017-01-01

    The current research identifies the range of social media brand behaviors (i.e., brand touch points) that consumers can exhibit on social media, and subsequently queries a representative sample of consumers with regard to such behaviors. The analysis reveals four underlying motivators for consumers’ social media behaviors, including brand tacit engagement, brand exhibiting, brand patronizing and brand deal seeking. These motivators are used to derive meaningful consumer segments identified as...

  10. Smoking Media Literacy in Vietnamese Adolescents

    Science.gov (United States)

    Page, Randy M.; Huong, Nguyen T.; Chi, Hoang K.; Tien, Truong Q.

    2011-01-01

    Background: Smoking media literacy (SML) has been found to be independently associated with reduced current smoking and reduced susceptibility to future smoking in a sample of American adolescents, but not in other populations of adolescents. Thus, the purpose of this study was to assess SML in Vietnamese adolescents and to determine the…

  11. Study of benzene release from Savannah River in-tank precipitation process slurry simulant

    International Nuclear Information System (INIS)

    Rappe, K.G.; Gauglitz, P.A.

    1998-08-01

    At the Savannah River Site, the in-tank precipitation (ITP) process uses sodium tetraphenylborate (NaTPB) to precipitate radioactive cesium from alkaline wastes. During this process, potassium is also precipitated to form 4-wt% KTPB/CsTPB slurry. Residual NaTPB decomposes to form benzene, which is retained by the waste slurry. The retained benzene is also readily released from the waste during subsequent waste processing. While the release of benzene certainly poses flammability and toxicological safety concerns, the magnitude of the hazard depends on the rate of release. Currently, the mechanisms controlling the benzene release rates are not well understood, and predictive models for estimating benzene release rates are not available. The overall purpose of this study is to obtain quantitative measurements of benzene release rates from a series of ITP slurry simulants. This information will become a basis for developing a quantitative mechanistic model of benzene release rates. The transient benzene release rate was measured from the surface of various ITP slurry (solution) samples mixed with benzene. The benzene release rate was determined by continuously purging the headspace of a sealed sample vessel with an inert gas (nitrogen) and analyzing that purged headspace vapor for benzene every minute

  12. Media Ecology

    Directory of Open Access Journals (Sweden)

    Marina Ašković

    2015-05-01

    Full Text Available Does the trend in which electronic media are gradually becoming extension of human body have to move towards full enslavement of a human and his personality, or the same human will unpredictably, with the aid of his personal media literacy, exit the whirls of media and technological censorships? Personality crisis is closely related to the crisis of language no matter how contradicted to global ideology of transnational transhumanism it may seem. Considering the fact that recent media presentations of the world are based on commercialization of environmentalism, philosophical and aesthetic thought appears as an important subject of ecology. As media mediates, the scenery of civilized living increasingly becomes more appealing even though it derives from commercial and political background. Consequently, the future of humanity depends by large on the philosophy of media. Media have to truly ecologise returning the humanum to its essence making it into the extension of the natural world.

  13. A Comparative Study on New Media Marketing in Domestic and Foreign Public Libraries

    Directory of Open Access Journals (Sweden)

    Xu Yan

    2017-01-01

    Full Text Available Currently, new media has become the popular platform for brand marketing and services promoting of public libraries. Using the method of online survey, literature analysis and comparative analysis, this paper chooses 4 foreign public libraries and 4 domestic public libraries as the research samples and compares the differences in new media marketing between them from new media marketing tools, marketing content and marketing strategies, then makes some proposals and measures to perfect domestic public libraries’ new media marketing, so as to provide references to improve the libraries’ social awareness and benefits.

  14. The effect of pH, buffer capacity and ionic strength on quetiapine fumarate release from matrix tablets prepared using two different polymeric blends.

    Science.gov (United States)

    Hamed, Rania; AlJanabi, Reem; Sunoqrot, Suhair; Abbas, Aiman

    2017-08-01

    The objective of this study was to investigate the effect of the different physiological parameters of the gastrointestinal (GI) fluid (pH, buffer capacity, and ionic strength) on the in vitro release of the weakly basic BCS class II drug quetiapine fumarate (QF) from two once-a-day matrix tablet formulations (F1 and F2) developed as potential generic equivalents to Seroquel ® XR. F1 tablets were prepared using blends of high and low viscosity grades of hydroxypropyl methylcellulose (HPMC K4M and K100LV, respectively), while F2 tablets were prepared from HPMC K4M and PEGylated glyceryl behenate (Compritol ® HD5 ATO). The two formulations attained release profiles of QF over 24 h similar to that of Seroquel ® XR using the dissolution medium published by the Food and Drug Administration (FDA). A series of solubility and in vitro dissolution studies was then carried out using media that simulate the gastric and intestinal fluids and cover the physiological pH, buffer capacity and ionic strength range of the GIT. Solubility studies revealed that QF exhibits a typical weak base pH-dependent solubility profile and that the solubility of QF increases with increasing the buffer capacity and ionic strength of the media. The release profiles of QF from F1, F2 and Seroquel ® XR tablets were found to be influenced by the pH, buffer capacity and ionic strength of the dissolution media to varying degrees. Results highlight the importance of studying the physiological variables along the GIT in designing controlled release formulations for more predictive in vitro-in vivo correlations.

  15. Media Education and Media Criticism in the Educational Process in Russia

    Science.gov (United States)

    Fedorov, Alexander; Levitskaya, Anastasia

    2017-01-01

    Media criticism and media education have a lot in common. For example, both media education and media criticism attach great importance to the development of analytical thinking of the audience. Indeed, one of the most important tasks of media education is precisely to teach the audience not only to analyze media texts of any types, but also to…

  16. Small sample whole-genome amplification

    Science.gov (United States)

    Hara, Christine; Nguyen, Christine; Wheeler, Elizabeth; Sorensen, Karen; Arroyo, Erin; Vrankovich, Greg; Christian, Allen

    2005-11-01

    Many challenges arise when trying to amplify and analyze human samples collected in the field due to limitations in sample quantity, and contamination of the starting material. Tests such as DNA fingerprinting and mitochondrial typing require a certain sample size and are carried out in large volume reactions; in cases where insufficient sample is present whole genome amplification (WGA) can be used. WGA allows very small quantities of DNA to be amplified in a way that enables subsequent DNA-based tests to be performed. A limiting step to WGA is sample preparation. To minimize the necessary sample size, we have developed two modifications of WGA: the first allows for an increase in amplified product from small, nanoscale, purified samples with the use of carrier DNA while the second is a single-step method for cleaning and amplifying samples all in one column. Conventional DNA cleanup involves binding the DNA to silica, washing away impurities, and then releasing the DNA for subsequent testing. We have eliminated losses associated with incomplete sample release, thereby decreasing the required amount of starting template for DNA testing. Both techniques address the limitations of sample size by providing ample copies of genomic samples. Carrier DNA, included in our WGA reactions, can be used when amplifying samples with the standard purification method, or can be used in conjunction with our single-step DNA purification technique to potentially further decrease the amount of starting sample necessary for future forensic DNA-based assays.

  17. The Duality of Social Media in Tourism

    Directory of Open Access Journals (Sweden)

    Irina Maiorescu

    2014-11-01

    Full Text Available Today’s technologies offer many opportunities for communication and for developing the social, political and economic environments. Social media is one of the channels highly used for personal and business communication in our informational society. However, the various facets of the social media may not be employed in the same manner for the needs of the individual as they are for the needs of the businesses aiming to develop in the tourism sector. This paper aims to identify which of the social media platforms are appropriate for being used for personal purposes and which are more suitable for developing a business in tourism, amongst the users of social media. The paper bases its conclusions on a survey applied on a sample of Romanian young people (18 – 35 years old involved in tourism business environment, as according to research in the field such as Lenhart, Purcell, Smith and Zichur (2010 and Cabral (2011 this is the most active segment in social media. The findings presented in the paper result from the analysis of the survey responses and they indicate that all four types of social media platforms taken into account: social networks, blogs, micro-blogs and video file sharing platforms are used for both personal and business purposes. However, inside each of the four types of platforms surveyed there were noticed certain preferences, from the point of view of users’ interests in communication: personal purpose communication or business in tourism purpose communication.

  18. Media Bias and Advertising: Evidence from German Car Magazines

    OpenAIRE

    Dewenter, Ralf; Heimeshoff, Ulrich

    2011-01-01

    This paper investigates the existence of a possible media bias by analyzing the impact of automobile manufactures' advertisements on automobile reviews in German car magazines. By accounting for both endogeneity and sample selection we find a positive impact of advertising volumes on test scores. Moreover, also a home bias in terms of higher scores for German cars is observable. We account these results as some evidence for a media bias, induced by the two-sidedness of the markets.

  19. Magnetic properties of soft layer/FePt-MgO exchange coupled composite Perpendicular recording media

    Institute of Scientific and Technical Information of China (English)

    Yin Jin-Hua; Takao Suzuki; Pan Li-Qing

    2008-01-01

    The magnetic properties of exchange coupled composite(ECC)media that are composed of perpendicular magnetic recording media FePt-MgO and two kinds of soft layers have been studied by using an x-ray diffractometer,a polar Kerr magneto-optical system(PMOKE)and a vibrating sample magnetometer(VSM).The results show that ECC media can reduce the coercivities of perpendicular magnetic recording media FePt-MgO.The ECC media with granular-type soft layers have weaker exchange couplings between magnetic grains and the magnetization process,for ECC media of this kind mainly follow the Stoner-Wohlfarth model.

  20. Geographic Media Literacy

    Science.gov (United States)

    Lukinbeal, Chris

    2014-01-01

    While the use of media permeates geographic research and pedagogic practice, the underlying literacies that link geography and media remain uncharted. This article argues that geographic media literacy incorporates visual literacy, information technology literacy, information literacy, and media literacy. Geographic media literacy is the ability…

  1. The mass media are an important context for adolescents' sexual behavior.

    Science.gov (United States)

    L'Engle, Kelly Ladin; Brown, Jane D; Kenneavy, Kristin

    2006-03-01

    This study compared influences from the mass media (television, music, movies, magazines) on adolescents' sexual intentions and behaviors to other socialization contexts, including family, religion, school, and peers. A sample of 1011 Black and White adolescents from 14 middle schools in the Southeastern United States completed linked mail surveys about their media use and in-home Audio-CASI interviews about their sexual intentions and behaviors. Analysis of the sexual content in 264 media vehicles used by respondents was also conducted. Exposure to sexual content across media, and perceived support from the media for teen sexual behavior, were the main media influence measures. Media explained 13% of the variance in intentions to initiate sexual intercourse in the near future, and 8-10% of the variance in light and heavy sexual behaviors, which was comparable to other contexts. Media influences also demonstrated significant associations with intentions and behaviors after all other factors were considered. All contextual factors, including media, explained 54% of the variance in sexual intentions and 21-33% of the variance in sexual behaviors. Adolescents who are exposed to more sexual content in the media, and who perceive greater support from the media for teen sexual behavior, report greater intentions to engage in sexual intercourse and more sexual activity. Mass media are an important context for adolescents' sexual socialization, and media influences should be considered in research and interventions with early adolescents to reduce sexual activity.

  2. NucNet's growing impact on the media

    Energy Technology Data Exchange (ETDEWEB)

    Carle, Remy [Electricite de France (France)

    1995-07-01

    In the four years since the birth of NucNet there has been a gradual but radical change In the original concept of the network. In the beginning, the focus of attention was to make nuclear communicators better-informed and more efficient. What had been desperately needed for some time was an Information exchange system which would enable those communicators to do a better Job whether working proactlvely or reactively. The idea was primarily for positive nuclear news from Europe to be disseminated to people on the network so that they could pass it on to media contacts in their respective countries, as part of their regular dialogue with journalists. However, once NucNet was up-and-running a strong body of opinion emerged, arguing in favour of NucNet's most urgent, important or off-beat news - the 'A' category releases - to be sent direct to national and international news agencies. Quite rightly, it was felt that, in this way, the nuclear community could clearly demonstrate Its transparency and Its desire to Inform the public openly. At the same time, it was clear that sending to just a few national news agencies in Europe would not be enough. It was clear that NucNet would have to expand into a truly worldwide network and that, to reflect this, the main International news agencies would have to be put online as well. NucNet's growing impact on the media is a result of teamwork, and this teamwork takes different forms. It is: between the network's information suppliers and Central Office, among the Central Office staff themselves, between Central Office and the agencies, and between network members and their news media contacts. Through this continuing teamwork process, NucNet will achieve its goal of providing the media and the public with a balanced picture of nuclear energy.

  3. NucNet's growing impact on the media

    International Nuclear Information System (INIS)

    Carle, Remy

    1995-01-01

    In the four years since the birth of NucNet there has been a gradual but radical change In the original concept of the network. In the beginning, the focus of attention was to make nuclear communicators better-informed and more efficient. What had been desperately needed for some time was an Information exchange system which would enable those communicators to do a better Job whether working proactlvely or reactively. The idea was primarily for positive nuclear news from Europe to be disseminated to people on the network so that they could pass it on to media contacts in their respective countries, as part of their regular dialogue with journalists. However, once NucNet was up-and-running a strong body of opinion emerged, arguing in favour of NucNet's most urgent, important or off-beat news - the 'A' category releases - to be sent direct to national and international news agencies. Quite rightly, it was felt that, in this way, the nuclear community could clearly demonstrate Its transparency and Its desire to Inform the public openly. At the same time, it was clear that sending to just a few national news agencies in Europe would not be enough. It was clear that NucNet would have to expand into a truly worldwide network and that, to reflect this, the main International news agencies would have to be put online as well. NucNet's growing impact on the media is a result of teamwork, and this teamwork takes different forms. It is: between the network's information suppliers and Central Office, among the Central Office staff themselves, between Central Office and the agencies, and between network members and their news media contacts. Through this continuing teamwork process, NucNet will achieve its goal of providing the media and the public with a balanced picture of nuclear energy

  4. Multi-scale simulation for homogenization of cement media

    International Nuclear Information System (INIS)

    Abballe, T.

    2011-01-01

    To solve diffusion problems on cement media, two scales must be taken into account: a fine scale, which describes the micrometers wide microstructures present in the media, and a work scale, which is usually a few meters long. Direct numerical simulations are almost impossible because of the huge computational resources (memory, CPU time) required to assess both scales at the same time. To overcome this problem, we present in this thesis multi-scale resolution methods using both Finite Volumes and Finite Elements, along with their efficient implementations. More precisely, we developed a multi-scale simulation tool which uses the SALOME platform to mesh domains and post-process data, and the parallel calculation code MPCube to solve problems. This SALOME/MPCube tool can solve automatically and efficiently multi-scale simulations. Parallel structure of computer clusters can be use to dispatch the more time-consuming tasks. We optimized most functions to account for cement media specificities. We presents numerical experiments on various cement media samples, e.g. mortar and cement paste. From these results, we manage to compute a numerical effective diffusivity of our cement media and to reconstruct a fine scale solution. (author) [fr

  5. Toxic chemical considerations for tank farm releases. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Van Keuren, J.C.

    1995-11-01

    This document provides a method of determining the toxicological consequences of accidental releases from Hanford Tank Farms. A determination was made of the most restrictive toxic chemicals that are expected to be present in the tanks. Concentrations were estimated based on the maximum sample data for each analyte in all the tanks in the composite. Composite evaluated were liquids and solids from single shell tanks, double shell tanks, flammable gas watch list tanks, as well as all solids, all liquids, head space gases, and 241-C-106 solids. A sum of fractions of the health effects was computed for each composite for unit releases based emergency response planning guidelines (ERPGs). Where ERPGs were not available for chemical compounds of interest, surrogate guidelines were established. The calculation method in this report can be applied to actual release scenarios by multiplying the sum of fractions by the release rate for continuous releases, or the release amount for puff releases. Risk guidelines are met if the product is less than for equal to one.

  6. Toxic chemical considerations for tank farm releases. Revision 1

    International Nuclear Information System (INIS)

    Van Keuren, J.C.

    1995-11-01

    This document provides a method of determining the toxicological consequences of accidental releases from Hanford Tank Farms. A determination was made of the most restrictive toxic chemicals that are expected to be present in the tanks. Concentrations were estimated based on the maximum sample data for each analyte in all the tanks in the composite. Composite evaluated were liquids and solids from single shell tanks, double shell tanks, flammable gas watch list tanks, as well as all solids, all liquids, head space gases, and 241-C-106 solids. A sum of fractions of the health effects was computed for each composite for unit releases based emergency response planning guidelines (ERPGs). Where ERPGs were not available for chemical compounds of interest, surrogate guidelines were established. The calculation method in this report can be applied to actual release scenarios by multiplying the sum of fractions by the release rate for continuous releases, or the release amount for puff releases. Risk guidelines are met if the product is less than for equal to one

  7. Decomposition and particle release of a carbon nanotube/epoxy nanocomposite at elevated temperatures

    International Nuclear Information System (INIS)

    Schlagenhauf, Lukas; Kuo, Yu-Ying; Bahk, Yeon Kyoung; Nüesch, Frank; Wang, Jing

    2015-01-01

    Carbon nanotubes (CNTs) as fillers in nanocomposites have attracted significant attention, and one of the applications is to use the CNTs as flame retardants. For such nanocomposites, possible release of CNTs at elevated temperatures after decomposition of the polymer matrix poses potential health threats. We investigated the airborne particle release from a decomposing multi-walled carbon nanotube (MWCNT)/epoxy nanocomposite in order to measure a possible release of MWCNTs. An experimental set-up was established that allows decomposing the samples in a furnace by exposure to increasing temperatures at a constant heating rate and under ambient air or nitrogen atmosphere. The particle analysis was performed by aerosol measurement devices and by transmission electron microscopy (TEM) of collected particles. Further, by the application of a thermal denuder, it was also possible to measure non-volatile particles only. Characterization of the tested samples and the decomposition kinetics were determined by the usage of thermogravimetric analysis (TGA). The particle release of different samples was investigated, of a neat epoxy, nanocomposites with 0.1 and 1 wt% MWCNTs, and nanocomposites with functionalized MWCNTs. The results showed that the added MWCNTs had little effect on the decomposition kinetics of the investigated samples, but the weight of the remaining residues after decomposition was influenced significantly. The measurements with decomposition in different atmospheres showed a release of a higher number of particles at temperatures below 300 °C when air was used. Analysis of collected particles by TEM revealed that no detectable amount of MWCNTs was released, but micrometer-sized fibrous particles were collected

  8. Decomposition and particle release of a carbon nanotube/epoxy nanocomposite at elevated temperatures

    Science.gov (United States)

    Schlagenhauf, Lukas; Kuo, Yu-Ying; Bahk, Yeon Kyoung; Nüesch, Frank; Wang, Jing

    2015-11-01

    Carbon nanotubes (CNTs) as fillers in nanocomposites have attracted significant attention, and one of the applications is to use the CNTs as flame retardants. For such nanocomposites, possible release of CNTs at elevated temperatures after decomposition of the polymer matrix poses potential health threats. We investigated the airborne particle release from a decomposing multi-walled carbon nanotube (MWCNT)/epoxy nanocomposite in order to measure a possible release of MWCNTs. An experimental set-up was established that allows decomposing the samples in a furnace by exposure to increasing temperatures at a constant heating rate and under ambient air or nitrogen atmosphere. The particle analysis was performed by aerosol measurement devices and by transmission electron microscopy (TEM) of collected particles. Further, by the application of a thermal denuder, it was also possible to measure non-volatile particles only. Characterization of the tested samples and the decomposition kinetics were determined by the usage of thermogravimetric analysis (TGA). The particle release of different samples was investigated, of a neat epoxy, nanocomposites with 0.1 and 1 wt% MWCNTs, and nanocomposites with functionalized MWCNTs. The results showed that the added MWCNTs had little effect on the decomposition kinetics of the investigated samples, but the weight of the remaining residues after decomposition was influenced significantly. The measurements with decomposition in different atmospheres showed a release of a higher number of particles at temperatures below 300 °C when air was used. Analysis of collected particles by TEM revealed that no detectable amount of MWCNTs was released, but micrometer-sized fibrous particles were collected.

  9. Decomposition and particle release of a carbon nanotube/epoxy nanocomposite at elevated temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Schlagenhauf, Lukas [Empa - Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Functional Polymers (Switzerland); Kuo, Yu-Ying; Bahk, Yeon Kyoung [Empa - Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Analytical Technologies (Switzerland); Nüesch, Frank [Empa - Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Functional Polymers (Switzerland); Wang, Jing, E-mail: Jing.Wang@ifu.baug.ethz.ch [Empa - Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Analytical Technologies (Switzerland)

    2015-11-15

    Carbon nanotubes (CNTs) as fillers in nanocomposites have attracted significant attention, and one of the applications is to use the CNTs as flame retardants. For such nanocomposites, possible release of CNTs at elevated temperatures after decomposition of the polymer matrix poses potential health threats. We investigated the airborne particle release from a decomposing multi-walled carbon nanotube (MWCNT)/epoxy nanocomposite in order to measure a possible release of MWCNTs. An experimental set-up was established that allows decomposing the samples in a furnace by exposure to increasing temperatures at a constant heating rate and under ambient air or nitrogen atmosphere. The particle analysis was performed by aerosol measurement devices and by transmission electron microscopy (TEM) of collected particles. Further, by the application of a thermal denuder, it was also possible to measure non-volatile particles only. Characterization of the tested samples and the decomposition kinetics were determined by the usage of thermogravimetric analysis (TGA). The particle release of different samples was investigated, of a neat epoxy, nanocomposites with 0.1 and 1 wt% MWCNTs, and nanocomposites with functionalized MWCNTs. The results showed that the added MWCNTs had little effect on the decomposition kinetics of the investigated samples, but the weight of the remaining residues after decomposition was influenced significantly. The measurements with decomposition in different atmospheres showed a release of a higher number of particles at temperatures below 300 °C when air was used. Analysis of collected particles by TEM revealed that no detectable amount of MWCNTs was released, but micrometer-sized fibrous particles were collected.

  10. ANALISIS CATEGORY ADVERTISING EXPENDITURE DAN CONSUMER MEDIA HABIT DI MEDIA TELEVISI DAN MEDIA CETAK

    Directory of Open Access Journals (Sweden)

    Zifwen Zifwen

    2011-08-01

    Full Text Available Normal 0 false false false MicrosoftInternetExplorer4 The purpose of the study is to identify the category of advertising expenditure and media habit on media advertising, especially on television and print ad such as newspapers, magazines and tabloids. The Data were collected  from Nielsen Media Research (NMR data base from a number of cities in Indonesia, such as Jakarta,Surabaya, Bandung, Semarang, Surabaya, Yogyakarta, Bali, Medan,Palembang and Makassar. There are three different type of data used to acquire the secondary data for the study: (1  Telescope (data collected for rating analysis January 1st, 2005 to March 31st, 2005, (2 Print scope (data collected from the readership of magazines, tabloids and newspaper January 1st, 2004 to December 31st, 2004 and (3 Ad quest (data collected from advertising expenditure for all categories. The data were collected, calculated and analyzed from January 1st, 2002 to December 31st, 2004. The purpose of the study is to uncover the trend of advertising budget from all categories on the television and print ads, in order to describe the consumption tendency of the people within advertising media. Index analysis and Biplot were used to analyze the data. Based on the result of advertising expenditure analysis of data, showing that all categories were completely different in the utilization of the media for advertisement. Some categories used mix media to support their campaign and others used a single media. Characteristic of the categories were strongly involved in the decision making in way of choosing and using the advertising media. The result of consumer media analysis found that the people habit were completely different and unique in media consumption. Different of age, sex and social economic status can create a different habit in term of hobbies and desire within the channel, programme, newspaper, magazines and the tabloids. Finally, to create an effective and efficient advertising activity

  11. Enteric-coated sustained-release nanoparticles by coaxial electrospray: preparation, characterization, and in vitro evaluation

    Science.gov (United States)

    Hao, Shilei; Wang, Bochu; Wang, Yazhou; Xu, Yingqian

    2014-02-01

    Enteric-coated formulations can delay the release of drugs until they have passed through the stomach. However, high concentration of drugs caused by rapidly released in the small intestine leads to the intestinal damage, and frequent administration would increase the probability of missing medication and reduce the patient compliance. To solve the above-mentioned problems, aspirin-loaded enteric-coated sustained-release nanoparticles with core-shell structure were prepared via one-step method using coaxial electrospray in this study. Eudragit L100-55 as pH-sensitive polymer and Eudragit RS as sustained-release polymer were used for the outer coating and inner core of the nanoparticles, respectively. The maximum loading capacity of nanoparticles was 23.66 % by changing the flow rate ratio of outer/inner solutions, and the entrapment efficiency was nearly 100 %. Nanoparticles with core-shell structure were observed via fluorescence microscope and transmission electron microscope. And pH-sensitive and sustained drug release profiles were observed in the media with different pH values (1.2 and 6.8). In addition, mild cytotoxicity in vitro was detected, and the nanoparticles could be taken up by Caco-2 cells within 1.0 h in cellular uptake study. These results indicate that prepared enteric-coated sustained-release nanoparticles would be a more safety and effective carrier for oral drug delivery.

  12. Joint importance sampling of low-order volumetric scattering

    DEFF Research Database (Denmark)

    Georgiev, Iliyan; Křivánek, Jaroslav; Hachisuka, Toshiya

    2013-01-01

    Central to all Monte Carlo-based rendering algorithms is the construction of light transport paths from the light sources to the eye. Existing rendering approaches sample path vertices incrementally when constructing these light transport paths. The resulting probability density is thus a product...... of the conditional densities of each local sampling step, constructed without explicit control over the form of the final joint distribution of the complete path. We analyze why current incremental construction schemes often lead to high variance in the presence of participating media, and reveal...... that such approaches are an unnecessary legacy inherited from traditional surface-based rendering algorithms. We devise joint importance sampling of path vertices in participating media to construct paths that explicitly account for the product of all scattering and geometry terms along a sequence of vertices instead...

  13. [Association of human chorionic gonadotropin level in embryo culture media with early embryo development].

    Science.gov (United States)

    Wang, Haiying; Zhang, Renli; Han, Dong; Liu, Caixia; Cai, Jiajie; Bi, Yanling; Wen, Anmin; Quan, Song

    2014-06-01

    To investigate the association of human chorionic gonadotropin (HCG) level on day 3 of embryo culture with embryo development. Spent culture media were collected from individually cultured embryos on day 3 of in vitro fertilization and embryo transfer (IVF-ET) cycles. HCG concentration in the culture media was measured using an ELISA kit and its association with embryo development was assessed. In the 163 samples of embryo culture media from 60 patients, HCG was positive in 153 sample (93.8%) with a mean level of 0.85 ± 0.43 mIU/ml. The concentration of hCG in the culture media increased gradually as the number of blastomeres increased (F=2.273, P=0.03), and decreased as the morphological grade of the embryo was lowered (F=3.900, P=0.02). ELISA is capable of detecting HCG levels in spent culture media of embryos on day 3 of in vitro culture. The concentration of HCG in spent culture media is positively correlated with the status of early embryo development and implantation rate and thus serves as a useful marker for embryo selection in IVF-ET procedure.

  14. Induction of Ca2+-dependent cyclosporin A-insensitive nonspecific permeability of the inner membrane of liver mitochondria and cytochrome c release by α,ω-hexadecanedioic acid in media of varying ionic strength.

    Science.gov (United States)

    Dubinin, M V; Vedernikov, A A; Khoroshavina, E I; Samartsev, V N

    2014-06-01

    In liver mitochondria loaded with Ca2+ or Sr(2+), α,ω-hexadecanedioic acid (HDA) can induce nonspecific permeability of the inner membrane (mitochondrial pore) by the mechanism insensitive to cyclosporin A (CsA). In this work we studied the effect of ionic strength of the incubation medium on the kinetics of the processes that accompany Ca2+-dependent induction of the mitochondrial pore by fatty acid: organelle swelling, Ca2+ release from the matrix, changes in transmembrane potential (Δψ) and rate of oxygen consumption, and the release of cytochrome c from the intermembrane space. Two basic incubation media were used: sucrose medium and isotonic ionic medium containing KCl without sucrose. We found that 200 μM Ca2+ and 20 μM HDA in the presence of CsA effectively induce high-amplitude swelling of mitochondria both in the case of sucrose and in the ionic incubation medium. In the presence of CsA, mitochondria can rapidly absorb Ca2+ and retain it in the matrix for a while without reducing Δψ. Upon incubation in the ionic medium, mitochondria retain most of the added Ca2+ in the matrix for a short time without reducing the Δψ. In both cases the addition of HDA to the mitochondria 2 min after the introduction of Ca2+ leads to the rapid release of these ions from the matrix and total drop in Δψ. The mitochondrial swelling induced by Ca2+ and HDA in non-ionic medium is accompanied by almost maximal stimulation of respiration. Under the same conditions, but during incubation of mitochondria in the ionic medium, it is necessary to add cytochrome c for significant stimulation of respiration. The mitochondrial swelling induced by Ca2+ and HDA leads to the release of cytochrome c in a larger amount in the case of ionic medium than for the sucrose medium. We conclude that high ionic strength of the incubation medium determines the massive release of cytochrome c from mitochondria and liberates it from the respiratory chain, which leads to blockade of electron

  15. Tannic acid promotes ion release of copper oxide nanoparticles: Impacts from solution pH change and complexation reactions.

    NARCIS (Netherlands)

    Zhao, Jing; Liu, Yang; Pan, Bo; Gao, Guoqian; Liu, Ying; Liu, Siqian; Liang, Ni; Zhou, Dandan; Vijver, Martina G; Peijnenburg, Willie J G M

    2017-01-01

    The increasing number of applications in which copper oxide nanoparticles (CuO NPs) are used, may lead to potential release of CuO NPs into the environment. However, the impact of natural organic matters on the behavior and fate of CuO NPs in aquatic media is still largely unknown. In this study,

  16. Release of ultrafine particles from three simulated building processes

    International Nuclear Information System (INIS)

    Kumar, Prashant; Mulheron, Mike; Som, Claudia

    2012-01-01

    Building activities are recognised to produce coarse particulate matter but less is known about the release of airborne ultrafine particles (UFPs; those below 100 nm in diameter). For the first time, this study has investigated the release of particles in the 5–560 nm range from three simulated building activities: the crushing of concrete cubes, the demolition of old concrete slabs, and the recycling of concrete debris. A fast response differential mobility spectrometer (Cambustion DMS50) was used to measure particle number concentrations (PNC) and size distributions (PNDs) at a sampling frequency of 10 Hz in a confined laboratory room providing controlled environment and near–steady background PNCs. The sampling point was intentionally kept close to the test samples so that the release of new UFPs during these simulated processes can be quantified. Tri–modal particle size distributions were recorded for all cases, demonstrating different peak diameters in fresh nuclei ( 4 cm −3 . These background modal peaks shifted towards the larger sizes during the work periods (i.e. actual experiments) and the total PNCs increased between 2 and 17 times over the background PNCs for different activities. After adjusting for background concentrations, the net release of PNCs during cube crushing, slab demolition, and ‘dry’ and ‘wet’ recycling events were measured as ∼0.77, 19.1, 22.7 and 1.76 (×10 4 ) cm −3 , respectively. The PNDs were converted into particle mass concentrations (PMCs). While majority of new PNC release was below 100 nm (i.e. UFPs), the bulk of new PMC emissions were constituted by the particles over 100 nm; ∼95, 79, 73 and 90% of total PNCs, and ∼71, 92, 93 and 91% of total PMCs, for cube crushing, slab demolition, dry recycling and wet recycling, respectively. The results of this study firmly elucidate the release of UFPs and raise a need for further detailed studies and designing health and safety related exposure guidelines for

  17. Endurance training enhances BDNF release from the human brain

    DEFF Research Database (Denmark)

    Seifert, Thomas; Brassard, Patrice; Wissenberg, Mads

    2010-01-01

    The circulating level of brain-derived neurotrophic factor (BDNF) is reduced in patients with major depression and type-2 diabetes. Because acute exercise increases BDNF production in the hippocampus and cerebral cortex, we hypothesized that endurance training would enhance the release of BDNF from...... the human brain as detected from arterial and internal jugular venous blood samples. In a randomized controlled study, 12 healthy sedentary males carried out 3 mo of endurance training (n = 7) or served as controls (n = 5). Before and after the intervention, blood samples were obtained at rest and during...... exercise. At baseline, the training group (58 + or - 106 ng x 100 g(-1) x min(-1), means + or - SD) and the control group (12 + or - 17 ng x 100 g(-1) x min(-1)) had a similar release of BDNF from the brain at rest. Three months of endurance training enhanced the resting release of BDNF to 206 + or - 108...

  18. Controlled release of simvastatin from biomimetic β-TCP drug delivery system.

    Directory of Open Access Journals (Sweden)

    Joshua Chou

    Full Text Available Simvastatin have been shown to induce bone formation and there is currently a urgent need to develop an appropriate delivery system to sustain the release of the drug to increase therapeutic efficacy whilst reducing side effects. In this study, a novel drug delivery system for simvastatin by means of hydrothermally converting marine exoskeletons to biocompatible beta-tricalcium phosphate was investigated. Furthermore, the release of simvastatin was controlled by the addition of an outer apatite coating layer. The samples were characterized by x-ray diffraction analysis, fourier transform infrared spectroscopy, scanning electron microscopy and mass spectroscopy confirming the conversion process. The in-vitro dissolution of key chemical compositional elements and the release of simvastatin were measured in simulated body fluid solution showing controlled release with reduction of approximately 25% compared with un-coated samples. This study shows the potential applications of marine structures as a drug delivery system for simvastatin.

  19. Normalized inverse characterization of sound absorbing rigid porous media.

    Science.gov (United States)

    Zieliński, Tomasz G

    2015-06-01

    This paper presents a methodology for the inverse characterization of sound absorbing rigid porous media, based on standard measurements of the surface acoustic impedance of a porous sample. The model parameters need to be normalized to have a robust identification procedure which fits the model-predicted impedance curves with the measured ones. Such a normalization provides a substitute set of dimensionless (normalized) parameters unambiguously related to the original model parameters. Moreover, two scaling frequencies are introduced, however, they are not additional parameters and for different, yet reasonable, assumptions of their values, the identification procedure should eventually lead to the same solution. The proposed identification technique uses measured and computed impedance curves for a porous sample not only in the standard configuration, that is, set to the rigid termination piston in an impedance tube, but also with air gaps of known thicknesses between the sample and the piston. Therefore, all necessary analytical formulas for sound propagation in double-layered media are provided. The methodology is illustrated by one numerical test and by two examples based on the experimental measurements of the acoustic impedance and absorption of porous ceramic samples of different thicknesses and a sample of polyurethane foam.

  20. Evaluation of particle release from montmorillonite gel by flowing groundwater based on the DLVO theory

    International Nuclear Information System (INIS)

    Kurosawa, Susumu; Nagasaki, Shinya; Tanaka, Satoru

    2007-01-01

    Theoretical study has been performed to clarify the ability of colloid release form the montmorillonite gel by the flowing groundwater. Evaluation of montmorillonite colloidal particles release from the bentonite buffer material is important for the performance assessment of radioactive waste disposal because the colloids may influence the radionuclide transport. In this study, the minimum groundwater flow rate required to tear off montmorillonite particles from surface of bentonite buffer was estimated from the shear stress on the gel front, which was calculated by the DLVO theory. The estimated shear force was converted to corresponding groundwater velocity by using Stoke's equation. The results indicated that groundwater velocity in a range of about 10 -5 to 10 -4 m/s would be necessary to release montmorillonite particles. This range is higher than the groundwater flow velocity found generally in deep geological media in Japan. This study suggests that the effect of montmorillonite particles release from the bentonite buffer on radionuclide transport is likely to be negligible in the performance assessment of high-level radioactive waste geological disposal. (author)