salmonid genetic resources: Topics by WorldWideScience.org

Technology assessment and resource allocation for predictive genetic testing: A study of the perspectives of Canadian genetic health care providers

Mouse genetic resources include inbred strains, recombinant inbred lines, chromosome substitution strains, heterogeneous stocks, and the Collaborative Cross (CC). These resources were generated through...Full Text Available

2007-07-01

2

Columbia River Coordinated Information System (CIS); Phase II Cooperative Agreement, 1992 Technical Report.

BackgroundWith a growing number of genetic tests becoming available to the health and consumer markets, genetic health care providers in Canada are faced with the challenge of developing...Full Text Available

3

Mice as a Mammalian Model for Research on the Genetics of Aging

Anadromous salmon in the Columbia River Basin are presently far below historic level of production, due to the impacts of development in the basin. To halt the downward trend in production and ultimately increase returns, the Northwest Power Planning Council developed the Columbia River Basin Fish and Wildlife Program. The Program outlines a coordinated plan for restoring anadromous salmonid runs to the basin. The goals and objectives outlined in the Program require addressing a complex set of problems that encompass a broad range of social, political, economic and biological issues. Resolution of these problems will require the efforts of a number of federal, state, and tribal agencies that have regulatory authority over activities that either directly or indirectly affect anadromous salmonids in the basin. Resource managers have realized the need for coordination in these efforts. The Coordinated Information System is ...

1993-05-01

4

Browse Conditions - Genetics Home Reference

Mice are an ideal mammalian model for studying the genetics of aging: considerable resources are available, the generation time is short, and the environment can be easily controlled, an important...Full Text Available

2011-02-08

5

Astaxanthin reduces ischemic brain injury in adult rats

Home A service of the U.S. National Library of Medicine® Home Conditions Genes Chromosomes Handbook Glossary Resources Genetic Conditions > Browse Conditions 1-9 | A | B | C...

2011-09-24

6

Incorporating Traditional Knowledge in an International Regime on Access to Genetic Resources and Benefit Sharing: Problems and Prospects

Astaxanthin (ATX) is a dietary carotenoid of crustaceans and fish that contributes to their coloration. Dietary ATX is important for development and survival of salmonids and crustaceans and has been...Full Text Available

2009-06-01

7

British Library Electronic Table of Contents (United Kingdom)

The Seventh Meeting of the Conference of the Parties (2004) of the Convention on Biological Diversity established a mandate for the negotiation of an international regime on Access to Genetic Resources and Benefit Sharing arising from their utilization. Negotiations have been proceeding and have entered the final phase. Seven working group meetings have been held to date and there is expectation that an instrument will emerge by the final deadline - the Tenth Meeting of the Conference of the Parties in Nagoya, Japan in October 2010. A key component singled out for inclusion in the international regime relates to the recognition and protection of the rights of indigenous and local communities (ILCs) over their traditional knowledge (TK) associated with genetic resources. The Ninth Meeting o...

2010-01-01

8

Technical approaches for mouse models of human disease

Genome-wide characterization of simple sequence repeats in cucumber (Cucumis sativus L.)

The mouse is the leading organism for disease research. A rich resource of genetic variation occurs naturally in inbred and special strains owing to spontaneous mutations. However, one can also obtain...Full Text Available

2011-05-01

9

Introduction to Genetic Algorithms

BackgroundCucumber, Cucumis sativus L. is an important vegetable crop worldwide. Until very recently, cucumber genetic and genomic resources, especially molecular...Full Text Available

10

Two-phase application of multi-objective genetic algorithms in green building design

Introduction to Genetic Algorithms

2007-01-01

11

Genetic structure of gilthead seabream, Sparus aurata, in the Central Mediterranean Sea

The application of multi-objective genetic algorithms for green building design in two phases were presented in order to better help designers in the decision-making process. The purpose is to minimize two conflicting criteria: the life-cycle cost and the life-cycle environmental impact. Environmental impact criteria examined include energy and non-energy natural resources, global warming, and acidification. Variables focus on building envelope-related parameters. The application of multi-objective genetic algorithms is divided into two phases. The first phase intends to help designers in understanding the trade-off relationship between the two conflicting criteria. The second phase intends to refine the performance region that is of the designer's interest. The results after the two-phase application of the multi objective genetic algorithm were then presented. 13 refs., 4 tabs., 3 figs.

2005-07-01

12

British Library Electronic Table of Contents (United Kingdom)

The gilthead seabream, Sparus aurata, represents an important economic resource for Mediterranean aquaculture. In spite of its wide geographic distribution and economic importance, only recently studies have been carried out on the genetic composition of natural populations, which have revealed a picture of a heterogeneous degree of genetic differentiation among S. aurata populations. In this study an allozyme analysis of samples from six different collecting sites along the Italian and Croatian coasts was carried out, covering an area in the Central Mediterranean sea that has yet to be investigated through gene-enzyme systems. Data on 26 gene loci, 10 of which are polymorphic, indicate a slight but significant genetic structure (FST = 0.0167) of the species. A hierarchical analysis of pop...

2006-01-01

13

Forest genetics: research and application in Indian forestry

Disturbance-mediated competition between perennial plants along a resource supply gradient

Sufficient genetic diversity exists in Indian tree species to give large genetic gains. Improvement potential, using wild gene resources for selection and breeding is vast as there are over 244 genera and 400 forest tree species in India. Of these over 30 species and 22 genera are of outstanding forestry value. Selective genetic-variation can be lifted from wild populations, multiplied vegetatively or by seed, and planted with controlled germplasm sources. Among the Indian species no less than 74 reproduce by cutting, 11 by layers, 9 by grafting and buding and 104 by root suckers. More than 161 species coppice vigorously. Afforestation techniques of over 170 species have been worked out. Tree genetic approach of survey of natural variability, quick evaluation, selection, conservation multiplication and planting superior variability directly in the field can give immediate ...

1981-04-01

14

British Library Electronic Table of Contents (United Kingdom)

Summary 1.-Traditional views of ecological disturbance emphasize the role that physical disturbances play in reducing competition between populations and maintaining species coexistence. I present an alternative view that employs a simple Lotka-Volterra model to demonstrate how disturbance resistance, disturbance resilience and resource storage can increase competition between individual perennial plants of similar growth form along a resource supply gradient. 2.-In contrasting the growth of individual genets of two hypothetical species, I assumed that traits associated with inherently low module (i.e. plant part) mortality in infertile soils resulted in greater resource storage, but traded off with maximum potential net photosynthesis rates and thus disturbance resilience. 3.-The species ...

2011-01-01

15

The genetic basis of salinity tolerance in Arctic charr (Salvelinus alpinus).

Monthly Status Report for Systems & Application Support for National Cancer Institute Center for Bioinformatics & Laboratory of Population Genetics

ABSTRACT: BACKGROUND: The capacity to maintain internal ion homeostasis amidst changing conditions is particularly important for teleost fishes whose reproductive cycle is dependent upon movement from freshwater to seawater. Although the physiology of seawater osmoregulation in mitochondria-rich cells of fish gill epithelium is well understood, less is known about the underlying causes of inter- and intraspecific variation in salinity tolerance. We used a genome-scan approach in Arctic charr (Salvelinus alpinus) to map quantitative trait loci (QTL) correlated with variation in four salinity tolerance performance traits and six body size traits. Comparative genomics approaches allowed us to infer whether allelic variation at candidate gene loci (e.g., ATP1alpha1b, NKCC1, CFTR, and cldn10e) could have underlain observed variation. RESULTS: Combined parental analyses yielded genome-wide significant QTL on linkage groups 8, 14 and 20 for salinity tolerance performance traits, and 1, 19, 20 ...

2011-09-21

16

Crop improvement of field vegetables

Assisted users with expired passwords Closed 233 NCICB Support Wizard Accounts Tickets Set up Resource Accounts for individual developers to control and track access on QA Application servers Maintained daily account synchronization between GForge project developers and CVS write access accounts Created FTP and SFTP user accounts for TCGA test, analysis datasets downloads and analysis datasets management.

17

Environmental Research Database

DescriptionThe main objective of the project is to develop a range of underpinning plant resources together with information about the level of genetic variability they represent, in a form suitable for use in crop improvement research in vegetable brassicas, lettuce and onion. The proposed research addresses Defra's requirement for a crop improvement programme to underpin research programmes aimed at Pest and Disease Control, Plant Nutrition and Quality in field vegetables at HRI. We will produc [continued...

2009-01-31

18

Genetic effects of introgression genomic components from Sea Island cotton (Gossypium barbadense L.) on fiber related traits in upland cotton (G. hirsutum L.)

British Library Electronic Table of Contents (United Kingdom)

The germplasm with exotic genomic components especially from Sea Island cotton (Gossypium barbadense L. Gb) is the dominant genetic resources to enhance fiber quality of upland cotton (G. hirsutum L., Gh). Due to low efficiency of phenotypic evaluation and selection on fiber quality, genetic dissection of favorable alleles using molecular markers is essential. Genetic dissection on putative Gb introgressions related to fiber traits were conducted by SSR markers with mapping populations derived from a cross between Luyuan343 (LY343), a superior fiber quality introgression line (IL) with genomic components from Gb, and an elite Upland cotton cv. Lumianyan#22 (LMY22). Among 82 polymorphic loci screened out from 4050 SSRs, 42 were identified as putative introgression alleles. A total of 29 fib...

2011-01-01

19

Assess Current and Potential Salmonid Production in Rattlesnake Creek Associated with Restoration Efforts; Yakama Indian Nation, Annual Report 2002-2003.

Prediction of the naturalisation potential and weediness risk of transgenic cotton in Australia

This document represents the FY2002 BPA contract Statement of Work for the Yakama Nation (YN) portion of the project entitled 'Assessment of current and potential salmonid production in Rattlesnake Creek associated with restoration efforts'. The purpose of the project is to complete detailed surveys of water quality, fish populations, habitat conditions and riparian health in the Rattlesnake Creek sub-basin of the White Salmon River in south central Washington. Results of the surveys will be used to establish Rattlesnake Creek sub-basin baseline environmental factors prior to anticipated removal of Condit Dam in 2006 and enable cost-effective formulation of future watershed restoration strategies.

2003-05-01

20

British Library Electronic Table of Contents (United Kingdom)

Climex climate-matching and inferential-modelling was used to examine the naturalisation potential of genetically modified and non-transgenic Upland Cotton (Gossypium hirsutum variety hirsutum) in Australia north of latitude 22degreeS. The Climate-Match (CM) function was used to identify locations in north-east Australia where climate matches (CM Index>0.7) the experimental sites of Eastick [Eastick, R., 2002. The Potential Weediness of Transgenic Cotton in Northern Australia. Northern Territory Department of Business, Industry and Resource Development Technical Bulletin No. 305 (Internet resource: http://cotton.pi.csiro.au/Assets/PDFFiles/TB3051.pdf)] in north-west Australia. Most of Australia north of 22degreeS had climate matching one or more of the sites of Eastick (2002), locations wh...

2007-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

21

Turbulence Investigation and Reproduction for Assisting Downstream Migrating Juvenile Salmonids, Part II of II; Effects of Induced Turbulence on Behavior of Juvenile Salmon, 2001-2005 Final Report.

Pop : Phonophani "Genetic Engineering" / Erkki Luuk

Passage through dams is a major source of mortality of anadromous juvenile salmonids because some populations must negotiate up to eight dams in Columbia and Snake rivers. Dams cause direct mortality when fish pass through turbines, but dams may also cause indirect mortality by altering migration conditions in rivers. Forebays immediately upstream of dams have decreased the water velocity of rivers and may contribute substantially to the total migration delay of juvenile salmonids. Recently, Coutant (2001a) suggested that in addition to low water velocities, lack of natural turbulence may contribute to migration delay by causing fish to lose directional cues. Coutant (2001a) further hypothesized that restoring turbulence in dam forebays may reduce migration delay by providing directional cues that allow fish to find passage routes more quickly (Coutant 2001a). Although field experiments have yielded proof of the concept of using induced ...

2005-07-01

22

Index Scriptorium Estoniae

Heliplaadist

2001-01-01

23

Effects of cryopreservation on germinability of olive (Olea europaea L.) pollen

British Library Electronic Table of Contents (United Kingdom)

Long term storage of viable pollen is important for bank germplasm constitution to preserve resources that can be used in breeding programs, biotechnologies and genetic engineering. Pollen from 12 olive (Olea europaea L.) cultivars was stored for 1?year in liquid nitrogen at ?196?C. The morphology of pollen grains and germination rates on fresh and long term stored pollen were observed. Results on in vitro pollen germinability, both before and after cryopreservation, showed highly significant responses among the 12 cultivars. The relationship between germinability and pollen grain size did not reveal any significant relationships in both treatments. Our findings will contribute to the improvement of olive pollen preservation and lead to find a more efficient method for its long term storag...

2011-01-01

24

Genetics, Genomics, and Molecular Biology

Less waste corn, more land in soybeans, and the switch to genetically modified crops: trends with important implications to wildlife management

Genetics, Genomics, and Molecular Biology USGS scientists develop and integrate new genetic and molecular techniques into systematic analyses to describe individuals and populations of fish .....

25

Molecular Genetics of Emericella nidulans Sexual Development

An abundance of waste corn, a key food of many wildlife species, has helped make possible the widespread success of wildlife management in the United States over the past half century. We found waste corn post harvest in Nebraska declined by 47% from 1978 to 1998 due primarily to improvements in combine headers resulting in a marked decline in ear loss. The reduction in waste coincided with major declines in fat storage by sandhill cranes and white-fronted geese during spring migration. Sandhill cranes, northern pintails, white-fronted geese, and lesser snow geese avoided soybeans while staging in spring in the Rainwater Basin Area and Central Platte River Valley. These findings and other literature suggest soybeans are a marginal food for wildlife particularly during periods of high energy requirements. Soybean acreage has increased by 600% in the United States since 1950 and now comprises nearly one-quarter of the nation>'s cropland. With over 80% of the soybean crop now in ...

2004-01-01

26

Genetic screening: The vista of genomic medicine

Full Text Available

2009-09-01

27

Server Complexity, A Model for Managing Resources

The accelerating development of biochemical and DNA-based diagnostic tests for human genetic conditions in the last decade has engendered a revolution in genetic diagnosis. Both genetic testing and...Full Text Available

2011-01-01

28

Survival Estimates for the Passage of Juvenile Salmonids through Snake River Dams and Reservoirs, 1996 Annual Report

No abstract prepared.

1999-12-01

29

Northeast coal study: resource planning framework, resource development status report. 3 Vols

In 1996, the National Marine Fisheries Service and the University of Washington completed the fourth year of a multi-year study to estimate survival of juvenile salmonids (Oncorhynchus spp.) passing through dams and reservoirs on the Snake River. Actively migrating smolts were collected near the head of Lower Granite Reservoir and at Lower Granite Dam, tagged with passive integrated transponder (PIT) tags, and released to continue their downstream migration. Individual smolts were subsequently detected at PIT-tag detection facilities at Lower Granite, Little Goose, Lower Monumental, McNary, John Day and Bonneville Dams. Survival estimates were calculated using the Single-Release (SR) and Paired-Release (PR) Models. Timing of releases of tagged hatchery steelhead (O. mykiss) from the head of Lower Granite Reservoir and yearling chinook salmon (O. tshawytscha) from Lower Granite Dam in 1996 spanned the major portion of their juvenile migrations. Specific research ...

1998-02-01

30

Consistent effects of a major QTL for thermal resistance in field-released Drosophila melanogaster.

The objective of this study was to provide a framework for land use and resource allocation decisions in the Northeast Coal Block of British Columbia. The area was divided into a number of sites, and information gathered in two main areas, 1) status of the resource base, and 2) resource management/planning/development. A map and physical description of each site is provided as well as such information as - air quality, soils, vegetation, water resources, petroleum and natural gas resources, coal resources, and gravel resources, agricultural resources, timber resources, fisheries and wildlife resources, recreatational and aesthetic (visual) resources. The appendix volume provides a summary of the institutional management framework and approval procedures for ...

1982-01-01

31

Assessing the Significance of Above- and Belowground Carbon Allocation of Fast- and Slow-Growing Families of Loblolly Pine - Final Report

Molecular genetic markers can be used to identify quantitative trait loci (QTL) for thermal resistance and this has allowed characterization of a major QTL for knockdown resistance to high temperature in Drosophila melanogaster. The QTL showed trade-off associations with cold resistance under laboratory conditions. However, assays of thermal tolerance conducted in the laboratory may not necessarily reflect performance at varying temperatures in the field. Here we tested if lines with different genotypes in this QTL show different thermal performance under high and low temperatures in the field using a release recapture assay. We found that lines carrying the QTL genotype for high thermal tolerance were significantly better at locating resources in the field releases under hot temperatures while the QTL line carrying the contrasting genotype were superior at cold temperatures. Further, we studied copulatory success between the different QTL ...

2011-06-15

32

Genetically-engineered mouse models for pancreatic cancer: Advances and current limitations

During this project we experimentally evaluated the below-ground biomass and carbon allocation and partitioning of four different fast- and slow-growing families of loblolly pine located in Scotland County, NC, in an effort to increase the long-term performance of the crop. The trees were subjected to optimal nutrition and control since planting in 1993. Destructive harvests in 1998 and 2000 were used for whole?plant biomass estimates and to identify possible family differences in carbon acquisition (photosynthesis) and water use efficiency. At regular intervals throughout each year we sampled tissues for carbohydrate analyses to assess differences in whole-tree carbon storage. Mini rhizotron observation tubes were installed to monitor root system production and turnover. Stable isotope analysis was used to examine possible functional differences in water and nutrient acquisition of root systems between the various families. A genetic dissection of root ontogenic ...

2001-03-01

33

From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis

Recently, there has been significant progress in the development of genetically-engineered mouse (GEM) models. By introducing genetic alterations and/or signaling alterations of human pancreatic cancer...Full Text Available

2011-05-10

34

Evolving hard problems: Generating human genetics datasets with a complex etiology

Gene expression data has been used in lieu of phenotype in both classical and quantitative genetic settings. These two disciplines have separate approaches to measuring and interpreting epistasis, which...Full Text Available

2008-03-01

35

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study

BackgroundA goal of human genetics is to discover genetic factors that influence individuals' susceptibility to common diseases. Most common diseases are thought to result from the...Full Text Available

36

Construction of a genome-wide human BAC-Unigene resource. Final progress report, 1989--1996

Partial epilepsies have a substantial heritability. However, the actual genetic causes are largely unknown. In contrast to many other common diseases for which genetic association-studies have successfully...Full Text Available

2010-07-01

37

THE BALDWIN EFFECT AND GENETIC ASSIMILATION: REVISITING TWO MECHANISMS OF EVOLUTIONARY CHANGE MEDIATED BY PHENOTYPIC ...

Currently, over 30,000 mapped STSs and 27,000 mapped Unigenes (non-redundant, unigene sets of cDNA representing EST clusters) are available for human alone. A total of 44,000 Unigene cDNA clones have been supplied by Research Genetics. Unigenes, or cDNAs are excellent resource for map building for two reasons. Firstly, they exist in two alternative forms -- as both sequence information for PCR primer pairs, and cDNA clones -- thus making library screening by colony hybridization as well as pooled library PCR possible. The authors have developed an efficient and robust procedure to screen genomic libraries with large number of DNA probes. Secondly, the linkage and order of expressed sequences, or genes are highly conserved among human, mouse and other mammalian species. Therefore, mapping with cDNA markers rather than random anonymous STSs will greatly facilitate comparative, evolutionary studies as well as physical map building. They have ...

1996-12-31

38

Ovine reference materials and assays for prion genetic testing

... 1111/j.1558-5646.2007.00203.x THE BALDWIN EFFECT AND GENETIC ASSIMILATION: REVISITING TWO MECHANISMS OF ... to phenotypic plast...

39

Molecular Genetics and Carcinogenesis Section

BackgroundGenetic predisposition to scrapie in sheep is associated with several variations in the peptide sequence of the prion protein gene (PRNP). DNA-based tests...Full Text Available

40

Liver Carcinogenesis Unit

The Molecular Genetics and Carcinogenesis Section conducts studies using human epithelial cells to assess: activation of proto-oncogenes by chemical and physical carcinogens; inactivation and dysregulation of tumor suppressor genes by chemical and physical

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

41

Detection of genetic mutations in repetitive DNA sequences in somatic human cells after low-dose irradiation

The Liver Carcinogenesis Section uses the modern technologies of molecular biology, cell biology, protein chemistry and genetics to investigate the biochemical and genetic pathways involved in human liver cancer.

42

APPLICATION OF RAPD IN THE DETERMINATION OF GENETIC FIDELITY IN MICROPROPAGATED DROSERA PLANTLETS

... 3-89701-147-6 0949-2224 245 p. animal cells dna genetic radiation effects

1998-03-01

43

Queensland resources of black coal, December 1988

... K. Ishii. 1998. Determination of genetic stability in long-term micropropagated shoots of Pinus thunbergii Parl. using RAPD markers. Plant ... ...

44

An Effective Grid Resource Management Model Based on Cloud Computing Platform

This assessment of Queensland's resources of black coal has been prepared by the Coal and Oil Shale Resources Assessment and Development Subprogram, Queensland Department of Mines, in accordance with the 'Code for Reporting of Identified Coal Resources and Reserves'.

1989-01-01

45

48 CFR 352.239-72 - Security requirements for Federal information technology resources.

Not Available

2011-02-01

46

The Integrated Status and Effectiveness Monitoring Program : Expansion of Existing Smolt Trapping Program and Steelhead Spawner Surveys : March 1st, 2008 - February 28th, 2009.

...requirements for Federal information technology resources. 352.239-72...requirements for Federal information technology resources. As prescribed...Requirements for Federal Information Technology Resources (January...

2010-10-01

47

Santa Cruz County Timber Resources

The Integrated Status and Effectiveness Monitoring Program (ISEMP - BPA project No.2003-0017) has been created as a cost effective means of developing protocols and new technologies, novel indicators, sample designs, analytical, data management and communication tools and skills, and restoration experiments that support the development of a region-wide Research, Monitoring and Evaluation (RME) program to assess the status of anadromous salmonid populations, their tributary habitat and restoration and management actions. The most straightforward approach to developing a regional-scale monitoring and evaluation program would be to increase standardization among status and trend monitoring programs. However, the diversity of species and their habitat, as well as the overwhelming uncertainty surrounding indicators, metrics, and data interpretation methods, requires the testing of multiple approaches. Thus, the approach ISEMP has adopted is to develop a broad template ...

2009-01-01

48

Trends and Controls on Summer Surface-Water Temperatures in Salmonid-Bearing Headwater Streams in Two Common Geomorphic Settings, Kenai Peninsula, Alaska

Timber Resources as defined in General Plan adopted May 24, 1994. Timberlands which are devoted to and ... ...

49

Stream temperature is an important physical characteristic of headwater streams that plays a critical role in the presence and health of juvenile salmonids. Headwater stream temperature was documented in two geomorphic settings on the Kenai Peninsula, Alaska, focusing on the variation in temperature induced by diffuse groundwater discharge and variable air temperature. Eighteen headwater stream reaches were studied in four watersheds, with 11 drainageway sites and seven discharge-slope sites. In drainageway sites, low-gradient streams flow through broad valleys with groundwater-fed fen wetlands; in discharge-slope sites, high-gradient streams flow through narrow valleys with groundwater-fed slope wetlands. At all 18 sites, hourly stream temperatures were measured for one year. At one drainageway and one discharge-slope site, groundwater temperatures, stream stages, and groundwater heads in the local groundwater flow systems were also measured hourly for a year. A ...

2010-12-01

50

Primaquine

Population genetic structure of savannah elephants in Kenya: conservation and management implications

... oxygen to the tissues in the body),nicotinamide adenine dinucleotide (NADH) deficiency (a genetic condition), glucose-6- ...

51

DEFF Research Database (Denmark)

Udgivelsesdato: null-null

2008-01-01

52

Genome structure of cotton revealed by a genome-wide SSR genetic map constructed from a BC₁population between gossypium hirsutum and G. barbadense

Genetically and somatically significant radiation doses in the radiotherapy of inflammatory and degenerative diseases

BackgroundCotton, with a large genome, is an important crop throughout the world. A high-density genetic linkage map is the prerequisite for cotton genetics and breeding. A genetic...Full Text Available

53

Genetic Stability of Magnaporthe oryzae during Successive Passages through Rice Plants and on Artificial Medium

... pathological changes patients radiation protection radiotherapy diseases

1982-10-25

54

Genetic Characterization of Encephalomyocarditis Virus Isolated from Aborted Swine Fetus in Korea

Full Text Available

2010-12-01

55

Proposals for the reporting of oil shale resources in Quennsland, Australia

Full Text Available

2006-10-01

56

Making resource recovery economical

While no mine in Queensland has yet extracted shale oil economically, large resources of oil shale are known to occur throughout the State. These resources have been reported to the Queensland Department of Resource Industries (formerly the Department of Mines) according to a number of different parameters, using numerous methods of calculation and in some instances, detailed and comprehensive supporting information has not been provided. This paper outlines present methods of calculation and reporting of oil shale resources. A more uniform system of reporting resources of Queensland oil shale is desirable to enable an accountable and reliable estimate of resources to be made. It is intended that a code for the reporting of identified oil shale resources based on the present Australian codes for the reporting of identified mineral and coal ...

1990-09-01

57

Ocean waves: energy resource assessment

Four major reasons why municipal resource recovery operations are uneconomical are analyzed. These reasons are: alternative municipal waste disposal methods are artificially underpriced when the costs of meeting modern environmental standards are considered; high capital costs related to the procurement of resource recovery systems and the marketing of recovered resources; uncertainties associated with the costs and performance of resource recovery technologies; and construction and operating risks of municipal waste resource recovery systems. If resource recovery is to become economical, purchasers of plants must develop innovative process designs and equipment and formulate new operating and maintenance procedures. (1 photo)

1980-01-01

58

Genetic diversity among Angus, American Brahman, Senepol and Romosinuano cattle breeds:

The aim of this paper is to provide a general view of wave energy resource assessment. First, a review of the origin of waves and the transformation they undergo as they propagate towards the coast through waters of decreasing depth is presented. Following this, the wave and wave-energy parameters and the statistics required for resource characterization are described. The various types of wave data and their usefulness for the present purposes are summarised. A common methodology for assessment of the wave energy resource is developed. Finally, a general description of the global open ocean resource is presented.

2002-12-31

59

British Library Electronic Table of Contents (United Kingdom)

Summary The objective of this study was to quantify the genetic diversity among breeds under evaluation for tropical adaptability traits that affect the performance of beef cattle at the USDA/ARS SubTropical Agricultural Research Station (STARS) near Brooksville, FL, USA. Twenty-six microsatellite loci were used to estimate parameters of genetic diversity among the breeds American Brahman, Angus, Senepol and Romosinuano; the latter was comprised of two distinct bloodlines (Costa Rican and Venezuelan). Genotypes of 47 animals from each of these STARS herds were analysed for genetic diversity and genetic distance. Using two methods, the greatest genetic distance was detected between the Costa Rican line of Romosinuano and the Senepol. Gene diversity ranged between 0.64 (Costa Rican line of R...

2007-01-01

60

Geothermal Resources - Utah Geological Survey

Zebrafish: A Model System for the Study of Eye Genetics

| Site Index open all | close all Get Adobe Acrobat Reader to view pdf files. ugs / geothermal resources Geothermal Resources Roosevelt Hot Springs, Beaver County. Nature of...

2007-02-14

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

61

Use of Forward Genetics to Discover Novel Regulators of NF-?B

Over the last decade, the use of the zebrafish as a genetic model has moved beyond the proof-of-concept for the analysis of vertebrate embryonic development to demonstrated utility as a mainstream...Full Text Available

2008-01-01

62

Tissue Effect on Genetic Control of Transcript Isoform Variation

Forward and reverse genetic experiments have both played important roles in revealing critical aspects of mammalian signal transduction pathways in cell culture experiments. Only recently have we begun...Full Text Available

2010-06-01

63

Survival of Genetically Modified and Self-Cloned Strains of Commercial Baker's Yeast in Simulated Natural Environments: Environmental Risk Assessment

Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals...Full Text Available

2009-08-01

64

Strategies for the production of genetically identical monkeys by embryo splitting

Although genetic engineering techniques for baker's yeast might improve the yeast's fermentation characteristics, the lack of scientific data on the survival of such strains in natural environments...Full Text Available

2005-11-01

65

Reproduction in three genetic lines of dairy cattle housed a total confinement system.

Genetically identical rhesus monkeys would have tremendous utility as models for the study of human disease and would be particularly valuable for vaccine trials and tissue transplantation studies where...Full Text Available

66

Radiation risks for medical applications

Dairy cattle of three genetic lines maintained year round in total confinement (either in loose housing or tie stall barn) were monitored for estrous cycle activity and reproductive performance. Only...Full Text Available

1981-10-01

67

RISK-XLR: A Microcomputer-Based Genetic Risk Program for X-Linked Recessive Traits

The achievements made in the field of radiation protection over the past 20 years are outlined. Risk analysis as applied to medicine is considered and genetic significant doses, genetic risks, somatic effective doses and somatic risks are discussed. (C.F.).

1980-05-31

68

Potential of plant genetic systems for monitoring and screening mutagens

A computer program, RISK-XLR, which calculates genetic risk for carrier status of a Mendelian X-linked recessive condition has been written for the Macintosh series of microcomputers. The program,...Full Text Available

1987-11-04

69

Persistence of genetic variants of the arctic fox strain of Rabies virus in southern Ontario

Plants have too long been ignored as useful screening and monitoring systems of environmental mutagens. However, there are about a dozen reliable, some even unique, plant genetic systems that can increase...Full Text Available

1978-12-01

70

Identification of inhibitors of auxin transcriptional activation by means of chemical genetics in Arabidopsis

AbstractGenetic-variant analysis of rabies viruses provides the most sensitive epidemiologic tool for following the spread and persistence of these viruses in their wildlife hosts. Since...Full Text Available

2006-01-01

71

Heritability of Measures of Kidney Disease Among Zuni Indians: The Zuni Kidney Project

Auxin modulates diverse plant developmental pathways through direct transcriptional regulation and cooperative signaling with other plant hormones. Genetic and biochemical approaches have clarified...Full Text Available

2004-10-12

72

Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens

BackgroundThe long-term goal of the GKDZI (Genetics of Kidney Disease in Zuni Indians) Study is to identify genes, environmental factors, and genetic-environmental...Full Text Available

2010-08-01

73

Genetic susceptibility to systemic lupus erythematosus in the genomic era

The continued evolution of bacterial pathogens has major implications for both human and animal disease, but the exchange of genetic material between host-restricted pathogens is rarely considered....Full Text Available

2009-03-01

74

Genetic relationship between anxiety- and fear -related behaviors in BXD recombinant inbred mice

Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been rapidly advanced using large-scale, case–control, candidate gene studies as well as genome-wide...Full Text Available

2010-12-01

75

Genetic predisposition for femoral neck stress fractures in military conscripts

Mood and anxiety disorders and rodent phenotypic measures modeling these disorders have a strong genetic component. Various assays are used to study the neurobiological basis of fear- and anxiety-related...Full Text Available

2009-03-01

76

Genetic evidence of illegal trade in protected whales links Japan with the US and South Korea

BackgroundStress fractures are a significant problem among athletes and soldiers and may result in devastating complications or even permanent handicap. Genetic factors may increase...Full Text Available

77

Genetic aspects of birth defects: new understandings of old problems

We report on genetic identification of ‘whale meat’ purchased in sushi restaurants in Los Angeles, CA (USA) in October 2009 and in Seoul, South Korea in June and September 2009. Phylogenetic...Full Text Available

2010-10-23

78

Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis

Over the past two decades, combined advances in genetics, developmental biology and biochemistry have transformed the study of human birth defects. This review describes the importance of genome architecture,...Full Text Available

2007-07-01

79

Genetic Monitoring and Evaluation Program for Supplemented Populations of Salmon and Steelhead in the Snake River Basin, 1990-1991 Annual Report.

The genetic architecture of complex traits underlying physiology and disease in most organisms remains elusive. We still know little about the number of genes that underlie these traits, the magnitude...Full Text Available

2008-12-16

80

Genetic Elucidation of Human Hyperosmia to Isovaleric Acid

This is the first report of research for an ongoing study to evaluate the genetic effects of using hatchery-reared fish to supplement natural populations of chinook salmon and steelhead in the Snake River Basin.

1991-08-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

81

Genetic Diversity Assessment of Rarely Cultivated Traditional Indica Rice (Oryza sativa L.) Varieties

The genetic basis of odorant-specific variations in human olfactory thresholds, and in particular of enhanced odorant sensitivity (hyperosmia), remains largely unknown. Olfactory receptor (OR) segregating...Full Text Available

2007-11-01

82

Energy metabolism of the untrained muscle of elite runners as observed by 31P magnetic resonance spectroscopy: evidence suggesting a genetic endowment for endurance exercise.

Random amplified polymorphic DNA fingerprinting was performed to assess the genetic diversity among rarely cultivated traditional indica rice (Oryza sativa ...Full Text Available

83

Effect of Feeding Cows Genetically Modified Maize on the Bacterial Community in the Bovine Rumen?

The purpose of this study was to investigate whether genetically determined properties of muscle metabolism contribute to the exceptional physical endurance of world-class distance runners. ATP, phosphocreatine,...Full Text Available

1988-12-01

84

Creating genetically modified pigs by using nuclear transfer

Rumen-cannulated cows (n = 4) were fed successively silage made from either conventional or genetically modified (GM) maize. Results revealed no effects of GM maize on the dynamics...Full Text Available

2007-12-01

85

Construction and Application of a Zebrafish Array CGH Platform

Nuclear transfer (NT) is a procedure by which genetically identical individuals can be created. The technology of pig somatic NT, including in vitro maturation of oocytes, isolation and treatment of...Full Text Available

86

Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease

The zebrafish is emerging as a prominent model system for studying the genetics of human development and disease. Genetic alterations that underlie each mutant model can exist in the form of...Full Text Available

2009-02-01

87

A Strong Case for Viral Genetic Factors in HIV Virulence

This study examined the genetic basis of hypertension and renal disease in Dahl SS/Mcwi (Dahl Salt-Sensitive) rats using a complete chromosome substitution panel of consomic rats in which each of the...Full Text Available

2008-09-01

88

A Cytogenetic Abnormality and Rare Coding Variants Identify ABCA13 as a Candidate Gene in Schizophrenia, Bipolar Disorder, and Depression

HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four...Full Text Available

89

Soil microbial toxicity of eight polycyclic aromatic compounds: effects on nitrification, the genetic diversity of bacteria, and the total number of protozoans.

Schizophrenia and bipolar disorder are leading causes of morbidity across all populations, with heritability estimates of ∼80% indicating a substantial genetic component. Population genetics...Full Text Available

2009-12-11

90

DEFF Research Database (Denmark)

Udgivelsesdato: 2002-Aug

2002-01-01

91

Primer for the Potato Specific Internal Control DNA and Screening Method for the Genetically Modified Potatoes by Competitive Duplex-PCR

Genetic Applications in Avian Conservation

Full Text Available

2002-12-01

92

Kenai River Salmon ... a Unique Resource in South-Central ...

... structure along an elevational gradient in Hawaiian honeycreepers reveals contrasting evolutionary responses to avian malaria. BMC Evolutionary Biology 8: ... ...

93

Kenai Fjords National Park Biological Resources Buffer Coverage

... Accession Number : ADA323711. Title : Kenai River Salmon ... a Unique Resource in South-Central Alaska. Descriptive ...

94

FFTF & Advance Reactors Transition Program Resource Loaded Schedule

... a buffer of all biological resources in the Kenai Fjords National Park Area. Data from Alaska Fish ... ...

95

Business groups' outward FDI: A managerial resources perspective

This document is the annual update of the FFTF and Advanced Reactors Transition Program Resource Loaded Schedule for FY 2002 using current project direction and authorized funding levels

2001-10-25

96

British Library Electronic Table of Contents (United Kingdom)

Outward FDI strategies are driven by firms' resource endowments, which in turn are conditioned by their home environment. In emerging economies, thus, the pattern of outward FDI is shaped by local firms' idiosyncratic contexts and the resources that these firms developed to fit the contexts. This includes business groups, a dominant organizational form in many emerging economies, competing with context-bound resources. When they wish to transcend their home context, they need internationally valuable resources, especially managerial resources, which may be quite different than the resources that enable domestic growth. This paper thus explores what resources drive this international growth in the case of Taiwanese business groups. Starting from Penrosian Theory, we focus on managerial reso...

2010-01-01

97

Genetic and somatic risks in X-ray diagnosis

Translational bioinformatics and healthcare informatics: computational and ethical challenges.

Based on a literature study an actual summary of the risk-utility problems in X-ray diagnosis is outlined due to the Recommendations of the International Commission for Radiation Protection (ICRP publication 26/1977). Papers demonstrating quantitative assessment of the somatic and genetical risk in X-ray examination are preferably cited and evaluated. It is concluded that the somatic and genetical risk is low in diagnostic ratiology. However, it must not be neglected and has always to be compared to the utility of an examination as well as to other risks of the examination. (author).

1982-01-01

98

Stochastic Kalman filtration as a method for predicting resource of steam generator pipes

Exponentially growing biological and bioinformatics data sets present a challenge and an opportunity for researchers to contribute to the understanding of the genetic basis of phenotypes. Due to breakthroughs in microarray technology, it is possible to simultaneously monitor the expressions of thousands of genes, and it is imperative that researchers have access to the clinical data to understand the genetics and proteomics of the diseased tissue. This technology could be a landmark in personalized medicine, which will provide storage for clinical and genetic data in electronic health records (EHRs). In this paper, we explore the computational and ethical challenges that emanate from the intersection of bioinformatics and healthcare informatics research. We describe the current situation of the EHR and its capabilities to store clinical and genetic data and then discuss the Genetic ...

2009-09-16

99

Secondary Titanium Processes

... p. SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS algorithms

100

International Science & Technology Center (ISTC)

Research and Development of Resource-Saving Technology for Manufacturing of Titanium Semifinished Items from Chips

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

101

Monitoring Coastal Marshes for Persistent Saltwater Intrusion

Environmental and resource economics in South Africa: status quo and lessons for developing countries

Primary goal: Provide resource managers with remote sensing products that support ecosystem

2009-01-01

102

CSIR Research Space (South Africa)

Full Text Available

103

EVALUATION OF THE WATER RESOURCES ASPECT OF THE OPERATING RESULTS OF THE DAECHEONG MULTIPURPOSE DAM

Dynamic Resource Coordination and Interference Management for Femtocell Networks

Full Text Available

2004-01-01

104

43 CFR 3251.12 - What action will BLM take on my Notice of Intent to Conduct Geothermal Resource Exploration...

Femtocell is emerging as a key technology to secure the coverage and capacity in indoor environments. However the deployment of a new femtocell layer may originate undesired interference to the whole system. This paper investigates spectrum resource coordination and interference management for the femtocell networks. A resource coordination scheme based on broadcasting resource coordination request messages by the femto mobile is proposed to reduce the system interference.

2010-01-01

105

Shallow oil shale resources of the southern Uinta Basin, Utah

...take on my Notice of Intent to Conduct Geothermal Resource Exploration Operations? ...INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCE LEASING Exploration Operations...take on my Notice of Intent to Conduct Geothermal Resource Exploration Operations?...

2010-10-01

106

Hanford Cultural Resources Laboratory annual report for fiscal year 1990

The shallow Green River Formation oil shales in the southern part of Utah's Uinta Basin are potentially developable by strip mining or by subsurface techniques which take advantage of limited overburden. The resource of potential shale oil represented by the shallow deposits is evaluated in detail from corehole oil-yield data. Cross-sections are constructed to readily correlatable stratigraphic units selected to represent resources in the shallow shale. To define each unit, the thickness, average oil yield, and oil resource of each unit in each core are calculated. Contour maps constructed from these data define the resource variation across the shallow resource. By measuring areas enclosed in each resource unit within the defined limit of 200 feet (61 meters) of overburden, the resource represented by the shallow oil shale is ...

1980-09-01

107

Genetic variability, heritability and genetic advance for seedling traits in sorghum genotypes

The Hanford Cultural Resources Laboratory (HCRL) was established by the US Department of Energy Field Office, Richland (RL) in 1987 as part of Pacific Northwest Laboratory. The HCRL provides support for managing the archaeological, historical, and cultural resources of the Hanford Site, Washington, in a manner consistent with federal statutes and regulations. This report summarizes activities of the HCRL during fiscal year (FY) 1990. The HCRL responsibilities have been set forth in the Hanford Cultural Resources Management Plan (HCRMP) as a prioritized list of tasks. The task list guided cultural resources management activities during FY 1990 and is the outline for this report. In order, these tasks were to (1) conduct cultural resource reviews, (2) develop an archaeological resources protection plan, (3) monitor the condition of known archaeological sites, (4) ...

1991-11-01

108

Exons, Introns and Talking Genes: The Sience Behind the Human Genome Project

Analysis of data on seedling traits from 20 diverse genotypes revealed significant differences fro most of the seedling traits. Significant estimates of broad-sense heritability were observed for VI, ERI, FRTW, DRTW and R/S ratio. Genetic advance was maximum for VI,ERI and E%. The correlation of VI with ERI and R/S ratio was negative and significant, whereas it was positive and significant with E%, FSHW and DSHW. Characterization of the sorghum genotypes according to Anderson's Metro glyph Statistics revealed five different groups for seedling trails. (authors)

1999-01-01

109

Resource assessment for geothermal direct use applications

This book presents in simple terms the basis of molecular genetics and how it is used to obtain an understanding of the human genome. The author's central focus is the transistion of genetics from statistics to experimental manipulations, and he offers analogies that help readers visualize the genome, thereby avoiding conventional scientific presentations. He illustrates how genetics is used in scientific laboratories, in courtrooms, and in hospitals. Little is presented about the complex social and ethical issues raised by the Human Genome project.

1993-01-01

110

Reciprocal and coincident patchiness of multiple resources differentially affect benefits of clonal integration in two perennial plants

This report discusses the topic geothermal resource assessment and its importance to laymen and investors for finding geothermal resources for direct-use applications. These are applications where the heat from lower-temperature geothermal fluids, 120 to 200/sup 0/F, are used directly rather than for generating electricity. The temperatures required for various applications are listed and the various types of geothermal resources are described. Sources of existing resource data are indicated, and the types and suitability of tests to develop more data are described. Potential development problems are indicated and guidance is given on how to decrease technical and financial risk and how to use technical consultants effectively. The objectives of this report are to provide: (1) an introduction low-temperature geothermal resource assessment; (2) experience from a series of recent ...

1984-04-01

111

British Library Electronic Table of Contents (United Kingdom)

Summary 1.-The modules of plants experience different levels of resources, and clonal plants can integrate resource heterogeneity. However, no studies have tested whether the benefits of clonal integration depend on patterns of heterogeneity in multiple resources, like high levels of above-ground and below-ground resources in the same patches (-coincident patchiness-) or different patches (-reciprocal patchiness-). 2.-We hypothesized that the benefits of clonal integration can vary depending on whether patchiness is reciprocal or coincident, and that clonal species experience greater benefits from integration when qualitative patterns of resource heterogeneity are more like those likely to occur in their habitats. To test these hypotheses, we grew pairs of connected ramets of Cynodon dacty...

2011-01-01

112

Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum

The evaluation of risks from radiation

BackgroundDuplications of stretches of the genome are an important source of individual genetic variation, but their unrecognized presence in laboratory organisms would be a confounding...Full Text Available

2008-01-01

113

The burden of genetically determined eye disease.

German translation of the publication 'The evaluation of risks from radiation' published in 1965 by the International Commission on Radiological Protection. In a survey, genetic and somatic risks from radiation are presented and explained. (HP).

1977-01-01

114

The biological aspects and behaviour of Heliothis virescens Fabricius adults from irradiated diapausal pupae

We determined the underlying aetiology of blindness for the registered blind population of the Province of Newfoundland and Labrador. In both 1981 and 1984 single-gene disorders accounted for 30% of...Full Text Available

1986-09-01

115

Telomeres and telomerase in cancer

... bollworm fertility gamma radiation genetic radiation effects life span mating

1974-07-22

116

Spatial Epidemiology: Current Approaches and Future Challenges

Myriad genetic and epigenetic alterations are required to drive normal cells toward malignant transformation. These somatic events commandeer many signaling pathways that cooperate to endow aspiring...Full Text Available

2010-01-01

117

Salicylate Metabolism in Twins

Spatial epidemiology is the description and analysis of geographic variations in disease with respect to demographic, environmental, behavioral, socioeconomic, genetic, and infectious risk factors....Full Text Available

2004-06-01

118

Role of the 5HT3 Receptor in Alcohol Drinking and ...

To evaluate the contribution of genetic influences on the individual variation in plateau serum salicylate levels, salicylate metabolism was studied in seven pairs of identical and six pairs of fraternal...Full Text Available

1977-07-01

119

Retinoids for Treatment of Retinal Diseases

... Proc Natl Acad Sci USA 97:11032-7 27. Duman RS 2002 Genetics of childhood disorders: XXXIX. Stem cell research, part 3: ...

2005-09-01

120

Principles of antibody therapy.

Knowledge about retinal photoreceptor signal transduction and the visual cycle required for normal eyesight has expanded exponentially over the past decade. Substantial progress in human genetics...Full Text Available

2010-06-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

121

Pharmacogenetics of aspirin resistance: a comprehensive systematic review

The success of monoclonal antibodies in clinical practice is dependent on good design. Finding a suitable target is the most important part as other properties of the antibody can be altered by genetic...Full Text Available

1992-12-05

122

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECTA genetic basis for aspirin resistance has been postulated to exist.The...Full Text Available

2008-08-01

123

POSTNOTE

Myxoviruses Monitoring in Seals Populations

the environment, with the 2006 release of a GM pink bollworm moth (a pest of cotton), ...Use of Genetically Engineered Fruit Fly and Pink Bollworm in APHIS Plant Pest Control Programs 6 Gould,

124

International Science & Technology Center (ISTC)

Comparative Molecular Genetic Monitoring of Myxoviruses Circulating in Populations of Seals Phoca Caspia and Phoca Sibirica in Northern Caspian Region and Lake Baikal

125

Mutations in RNA Binding Protein Gene Cause Familial Dilated Cardiomyopathy

Molecular based assessment of genetic diversity within Barbary fig (Opuntia ficus indica (L.) Mill.) in Tunisia

ObjectivesWe sought to identify a novel gene for dilated cardiomyopathy (DCM).BackgroundDCM is a heritable, genetically...Full Text Available

2009-09-01

126

British Library Electronic Table of Contents (United Kingdom)

In this work, we report for the first time on the analysis of genetic diversity within a set of 36 Tunisian Opuntia ficus indica (L.) Mill. ecotypes using RAPD markers.Random decamer primers were screened to assess their ability to detect polymorphisms in this plant crop. Thirty-nine RAPD markers were revealed and used to survey the genetic diversity at the DNA level and to establish relationships.Consequently, considerable genetic diversity was detected and the UPGMA analysis permitted the discrimination of all the genotypes and enabled their sorting into thirteen groups. The accession `R Sbiba inerme' was significantly divergent from all tested genotypes. In addition, as shown by the clustering the tested genotypes did not significantly diverge, though originating from different localiti...

2007-01-01

127

Microarray-based gene expression profiles of silkworm brains

Loss of genetic connectivity and diversity in urban microreserves in a southern California endemic Jerusalem cricket (Orthoptera: Stenopelmatidae: Stenopelmatus n. sp. ?santa monica??)

BackgroundMolecular genetic studies of Bombyx mori have led to profound advances in our understanding of the regulation of development. Bombyx mori brain,...Full Text Available

128

British Library Electronic Table of Contents (United Kingdom)

Microreserves may be useful in protecting native arthropod diversity in urbanized landscapes. However, species that do not disperse through the urban matrix may eventually be lost from these fragments. Population extinctions may be precipitated by an increase in genetic differentiation among fragments and loss of genetic diversity within fragments, and these effects should become stronger with time. We analyzed population genetic structure in the dispersal limited Jerusalem cricket Stenopelmatus n. sp. ?santa monica?? in the Santa Monica Mountains and Simi Hills north of Los Angeles, California (CA), to determine the impacts of fragmentation over the past 70 years. MtDNA divergence was greater among urban fragments than within contiguous habitat and was positively correlated with fragment ...

2009-01-01

129

Imaging immune response in vivo

Genomics of human longevity

PurposeClinical trials have commenced to evaluate the feasibility of targeting malignant gliomas with genetically engineered cytolytic T-cells (CTLs) delivered directly...Full Text Available

2008-06-15

130

Genetic Architecture Underlying Variation in Extent and Remodeling of the Collateral Circulation

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences...Full Text Available

2011-01-12

131

GENETIC STUDIES OF PIGMENTATION IN ...

RationaleCollaterals are arteriole-to-arteriole anastomoses that connect adjacent arterial trees. They lessen ischemic tissue injury by serving as endogenous bypass...Full Text Available

2010-08-20

132

Evidence for Epigenetic Interactions for Loci on Mouse Chromosome 1 Regulating Open Field Activity

... Strains Smith and -aybush were both grown in broth containing from 0.1 to 50 pg/ml of acriflavin, acridine orange, or proflavin. ...

1966-05-01

133

British Library Electronic Table of Contents (United Kingdom)

The expression of motor activity levels in response to novel situations is under complex genetic and environmental control. Several genetic loci have been implicated in the regulation of this behavioral phenotype, but their relationship to epigenetic and epistatic interactions is relatively unknown. Here, we report on a quantitative trait locus (QTL) on mouse chromosome 1 for novelty-induced motor activity in the open field, using chromosome substitution strains derived from a high active host strain (C57BL/6J) and a low active donor strain (A/J). The QTL for open field (horizontal distance moved) peaked at the location of Kcnj9, however, QTL detection was initially masked by an interplay of both grandparent genetic origin and genetic co-factors influencing behavior on chromosome 1. Our fi...

2009-01-01

134

Estimation of Genetic Parameters for Growth-Related Traits in 9-month Old of Two Korean Abalone Subspecies, Haliotis discus hannai and H. discus discus, by Using Multiple Traits of Animal Model

Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model

Full Text Available

2009-12-01

135

Distinct sensory representations of wind and near-field sound in the Drosophila brain

BackgroundMutations that disrupt the conversion of prelamin A to mature lamin A cause the rare genetic disorder Hutchinson-Gilford progeria syndrome and a group of laminopathies....Full Text Available

136

Current Projects - Human Nutrition Research Center on Aging ...

Behavioral responses to wind are thought to play a critical role in controlling the dispersal and population genetics of wild Drosophila species1,Full Text Available

2009-03-12

137

diet and genetic obesity metabolic defects and inflammation. To determine the role of adipocyte death in promoting adipose tissue inflammation and insulin resistance in animal...

2011-08-31

138

Culture and cooperation

Consumer attitudes and decision-making with regard to genetically engineered food products: A review of the literature and a presentation of models for future research

Does the cultural background influence the success with which genetically unrelated individuals cooperate in social dilemma situations? In this paper, we provide an answer by analysing the data of Full Text Available

2010-09-12

139

DEFF Research Database (Denmark)

Executive summary 1. Few studies have to date explained consumer attitudes and purchase decisions with regard to genetically engineered food products. However, the increased marketing of genetically engineered food products and the considerable concern that consumers seem to express with regard to the technology call for the development of a theoretical basis for research into these issues. 2. The aim of the paper is to present three models which we have developed to explain consumer attitudes, buying behaviour and attitude change with regard to genetically engineered food products. All three models build on established consumer behaviour theory and on existing and comparable research in the field. 3. Consumer attitudes toward genetic engineering in food products are explained in an attitude model that builds on Fishbein's multiattribute attitude model. The model deviates from Fishbein's model in a ...

1998-01-01

140

Comparing Genomes within the Species Mycobacterium tuberculosis

Combining Genetics and Population History in the Study of Ethnic Diversity in the People's Republic of China

The study of genetic variability within natural populations of pathogens may provide insight into their evolution and pathogenesis. We used a Mycobacterium tuberculosis high-density...Full Text Available

2001-04-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

141

Can microRNAs act as biomarkers of aging?

... some Central Asian populations (Zerjal et al. 2002). Haplogroup W has a similar Middle Eastern origin, and again ... ...

142

Allozyme Divergence in Two Syntopic Liolaemus of the Liolaemus monticola Group (Squamata: Tropiduridae)

Aging can be defined as a progressive decline in physiological efficiency regulated by an extremely complex multifactorial process. The genetic makeup of an individual appears to dictate this rate...Full Text Available

143

AEC syndrome - Genetics Home Reference

... shareware for population genetic analysis. Molecular Biology and Biotecnology Centre, Univ. of Alberta, Canada. enlarge figure Fig. ... ...

144

The effect of physician practice organization on efficient utilization of hospital resources.

What genes are related to AEC syndrome? AEC syndrome is caused by mutations in the TP63 gene. This gene provides instructions for making a protein known as p63, which plays an...

2011-10-15

145

Harnessing the geothermal resources of sedimentary basins for electricity production

OBJECTIVE. This study examines variations in the efficient use of hospital resources across individual physicians. DATA SOURCES AND SETTING. The study is conducted over a two-year period (1989-1990)...Full Text Available

1994-12-01

146

Earth Resources NASA SP-7041 (18) - NASA Technical Reports Server

Use of geothermal resources for generating electricity is briefly analyzed. Results obtained from optimization of the thermodynamic cycle implemented in the secondary coolant circuit of a binary geothermal power station and the parameters of its primary heat carrier circuit are presented.

2011-02-01

147

Biobank resources for future patient care: developments, principles and concepts

The Grover S and X-band dual-wavelength radar system has been ...... A. H. Watkins (U.S. Geological Survey, Earth Resources. Observation Systems Data Center ...

148

The aim of the overview is to give a perspective of global biobank development is given in a view of positioning biobanking as a key resource for healthcare to identify new potential markers that can...Full Text Available

149

BUBL LINK: Vietnam

... Author: Vets With A Mission Subjects: vietnam, vietnam war, warfare DeweyClass: 959.7043 Resource ... Subjects: vietnam, vietnam war DeweyClass: 959.7 Resource type: bibliography, index World Travel ...

150

BUBL LINK: Lung cancer

Aquatic Resource Monitoring

...2 Resource type: documents Mesothelioma Information HON-code certified resource, covering the main aspects of asbestos exposure: diagnosis, diseases caused by asbestos, treatment options, prevention and legal options. Diagrams are included in articles, and links are provided to the references used. Also contains a listing of ...

151

43 CFR 3200.6 - What types of geothermal leases will BLM issue?

...research strategy and plans Aquatic resource monitoring research programs, EMAP and STAR grants Go To EMAP homepage Go To Top Bibliography References for survey designs, statistical analyses , program documentation, and monitoring reports. Reports, abstracts and links to electronic versions Go To Top Frequently Asked Questions ...

152

...2010-10-01 2010-10-01 false What types of geothermal leases will BLM issue? 3200.6 Section...THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCE LEASING Geothermal Resource Leasing § 3200.6 What...

2010-10-01

153

The EMSL Collaboratory

Simultaneity: A Question of Time, Space, Resources and ...

sharing data and computational resources, and accessing information in digital libraries." Bill Wulf (1989) In a Collaboratory, the presentation/meeting concept embodied...

2011-10-07

154

Sunscreen

Medline Plus

... Animal & Veterinary Cosmetics Radiation-Emitting Products Tobacco Products Drugs Home > Drugs > Resources for You > Information for Consumers (Drugs) Section ...

155

NASA Information Technology Requirement Main Menu

... even divisions. ... hours on 25 October.62 The 82nd Airborne Division and a Marine Amphibious Unit followed the Rangers. ...

2001-05-01

156

Invasive Species Resources for Georgia

Headquarters Centrally-Funded Information Technology (IT) Resource Allocation .... Information Technology Policy Formulation Process ...

157

Implementation of a Federated Search System: Resource Accessibility Issues

... Southeastern Forests Feral Pig Fishes of Georgia: Georgia Freshwater Fish Distribution, Classification, and Information Flora of the Oconee National ... ...

158

British Library Electronic Table of Contents (United Kingdom)

During 2009, the Hilton M. Briggs Library, South Dakota State University, went live with MetaLib, a federated search engine from Ex Libris. This paper presents the implementation process, addresses resource accessibility issues, and suggests a number of resources that can be consulted about these issues. Readers can apply similar strategies to projects involving federated search systems, as many implementation projects involve the same basic considerations presented here. The author did not find any studies specifically focused on configurations of MetaLib resources, so this content should be singularly useful.

2009-01-01

159

Global Warming - Where You Live - Alabama

EPA: Environmental Quality and Recreation: Global Warming

... different information resources that have to do with global warming and its effects in the state of Alabama. ... ...

160

Development of a Colony of Germfree Hamsters as a ...

Archived Web resource. Information about the impacts of global warming on the environmental quality and recreation, such as ... ...

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

161

Decision Support for the Wartime Theater Ammunition ...

... Accession Number : ADA021166. Title : Development of a Colony of Germfree Hamsters as a Biomedical Resource. Descriptive Note : Final rept. ...

1976-01-07

162

Conservation of Louisiana's coastal wetland forests. p.117-135. In Proceedings of Louisiana Natural Resources Symposium

... A simulation of a military enga-gement might include objects representing Red and Blue maneuver units, physical resources, such as trucks or ...

1990-06-01

163

Congenital Adrenal Hyperplasia

No abstract prepared.

2005-01-01

164

Medline Plus

... Resources and Links Kid's Newsletter Listserv's Grandparent's Newsletter Networking Personal Stories by Affected Kids & Adults (currently not ...

165

BUBL LINK Catalogue of Internet Resources

Analysis of El Nino/ La Nina Impact on Korean Water Resources Using El Nino/ La Nina Influence Index

...O | P | Q | R | S | T | U | V | W | X | Y | Z 230 Christianity: general resources ...com: Christianity: General Anno Domini: Jesus Through the Centuries Bible and Homosexuality Christian Theological Research Fellowship Papers Christianity Links and Resources Directory ...Good Digital Collections Lambert's Web Links MUNDUS New Testament Gateway Omnilist of Christian Starting Points Quartz Hill School of Theology Web Library Theology Online ...com: Christianity: General Offers original articles and features about Christianity in general plus annotated links to selected relevant Internet resources, compiled by ...

166

Analyses of mixed hydrocarbon binary thermodynamic cycles for moderate temperature geothermal resources

Full Text Available

2000-05-01

167

Amarillo National Resource Center for Plutonium quarterly technical progress report, August 1, 1997--October 31, 1997

A dual-boiling isobutane cycle was selected for the present 5-megawatt (5MW) Raft River Pilot Plant to utilize the lower-temperature geothermal resources (near 300F). This study represents a second effort directed toward the design of an improved binary geothermal electric plant suitable for utilization of the lower temperature resources. 7 refs.

1981-08-01

168

Accessibility and Metadata in Digital Libraries

This report summarizes activities of the Amarillo National Resource Center for Plutonium during the quarter. The report describes the Electronic Resource Library; DOE support activities; current and future environmental health and safety programs; pollution prevention and pollution avoidance; communication, education, training, and community involvement programs; and nuclear and other material studies, including plutonium storage and disposition studies.

1997-12-31

169

Quantitative genetic activity graphical profiles for use in chemical evaluation

Metadata can be used to support accessibility in connection with improved discovery. ...certain metadata elements provide information about what capabilities are needed--either perceptual-motor, cognitive, socio-economic or geographic--to make use of a resource. This cam improve the ability of users who are disadvantaged in these ways to find resources that meet their needs--and avoid ones [resources] that do not.

2003-03-18

170

Optimal selection of capacitors for radial distribution systems using a genetic algorithm

A graphic approach, terms a Genetic Activity Profile (GAP), was developed to display a matrix of data on the genetic and related effects of selected chemical agents. The profiles provide a visual overview of the quantitative (doses) and qualitative (test results) data for each chemical. Either the lowest effective dose or highest ineffective dose is recorded for each agent and bioassay. Up to 200 different test systems are represented across the GAP. Bioassay systems are organized according to the phylogeny of the test organisms and the end points of genetic activity. The methodology for producing and evaluating genetic activity profile was developed in collaboration with the International Agency for Research on Cancer (IARC). Data on individual chemicals were compiles by IARC and by the US Environmental Protection Agency (EPA). Data are available on 343 compounds selected from volumes 1-53 of the IARC ...

1990-06-27

171

Nucleotide sequence and genetic analysis of a 13.1-kilobase-pair Pseudomonas denitrificans DNA fragment containing five cob genes and identification of structural genes encoding Cob(I)alamin adenosyltransferase, cobyric acid synthase, and bifunctional cobinamide kinase-cobinamide phosphate guanylyltransferase.

In this paper, a new design methodology for determining the size, location, type and number of capacitors to be placed on a radial distribution system is presented. The objective is to minimize the peak power losses and the energy losses in the distribution system considering the capacitor cost. A sensitivity analysis based method is used to select the candidate locations for the capacitors. A new optimization method using a Genetic Algorithm is proposed to determine the optimal selection of capacitors. Test results have been presented along with the discussion of the algorithm.

1994-08-01

172

Mobilization of the genetically engineered plasmid pHSV106 from Escherichia coli HB101(pHSV106) to Enterobacter cloacae in drinking water.

A 13.1-kb DNA fragment carrying Pseudomonas denitrificans cob genes has been sequenced. The nucleotide sequence and genetic analysis revealed that this fragment contained five different cob genes named...Full Text Available

1991-10-01

173

Liposome technology. Volume II: Incorporation of drugs, proteins and genetic material

We have used triparental matings to demonstrate transfer (mobilization) of the nonconjugative genetically engineered plasmid pHSV106, which contains the thymidine kinase gene of herpes simplex virus...Full Text Available

1991-01-01

174

Invasiveness and persistence of Salmonella enteritidis, Salmonella typhimurium, and a genetically defined S. enteritidis aroA strain in young chickens.

These three volumes cover liposome technology in pharmacology and medicine. Contributors emphasize methodology used in their own laboratories, and include a brief introduction, coverage of relevant literature, applications and critical evaluations for the methods they describe. Volume II presents procedures for the entrapment of a number of drugs, including genetic material, into selected types of liposomes.

1984-01-01

175

Genetics and biochemistry of Clostridium relevant to development of fermentation processes

Newly hatched chicks were dosed orally with a Salmonella typhimurium wild-type strain, an S. enteritidis wild-type strain, and a genetically defined S. enteritidis aroA vaccine candidate, strain CVL30....Full Text Available

1994-11-01

176

Genetic and somatic effects in animals maintained on tritiated water

It is the purpose of this review to draw together the recent research adding to our understanding of the molecular nature of Clostridia. The thrust here is to emphasize those research advances in biochemistry and genetics that bear upon future development of fermentation processes employing the Clostridia. 222 refs., 10 figs., 5 tabs.

1984-01-01

177

Generalized genetic code. A note on order-isomorphism/order-equivalence relations

The possible genetic (dominant lethal mutations (DLM) and cytogenetic changes in the regenerating liver) and somatic (hematopoietic stem cell changes, growth and nonspecific life time shortening) effects in mice maintained on tritiated water (HTO) over two generations was investigated. Results to date are summarized. (ACR)

1981-01-01

178

Estimation of organ dose during radiological and computer tomographic examinations with calculations of the somatically significant doses

Constructive and combinatorial relationships between order-isomorphisms and order-equivalence classes within the generalized genetic code are presented, not only for the biologically relevant groups of order 4, but also for finite groups of arbitrary order. The main result is the derivation of the number (and types) or order-equivalence classes for a group of order n. Finally, an extension of this work to all biologically admissible alternative codes is discussed.

1982-01-01

179

Estimation of organ dose during radiological and computer tomographic examinations with calculations of the somatically significant doses

The risks from radiation exposure during radiological diagnosis has usually been estimated in relation to genetic changes. Relevant information has been expressed as the genetically significant dose. In this paper we attempt to produce an analogous measure for evaluating the somatic risk in the form of a somatically significant dose index for radiological and CT examinations. It is shown that, for both types of examination, the two risk factors may be entirely different.

1980-10-01

180

Biological effects and health risks following to the exposition to ionizing radiation

The risks from radiation exposure during radiological diagnosis has usually been estimated in relation to genetic changes. Relevant information has been expressed as the genetically significant dose. In this paper we attempt to produce an analogous measure for evaluating the somatic risk in the form of a somatically significant dose index for radiological and CT examinations. It is shown that, for both types of examination, the two risk factors may be entirely different. (orig.).

1980-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

181

A Genetic Screen for Ribosomal DNA Silencing Defects Identifies Multiple DNA Replication and Chromatin-Modulating Factors

Late somatic and genetic radiation effects are imperfectly understood, particularly in the human species. However the available information is sufficient to draw reasonably precise risk estimates in man for many types of damage by means of scientifically justifiable procedures and with the necessary caution. This overall absolute risk of major somatic and genetic damage may be set at around 10"-"4/rad of chronic whole-body doses.

1976-01-01

182

Genetic studies of fertility and pathogenicity in Magnaporthe grisea (Pyricularia oryzae)

Transcriptional silencing in Saccharomyces cerevisiae occurs at several genetic loci, including the ribosomal DNA (rDNA). Silencing at telomeres (telomere position effect [TPE])...Full Text Available

1999-04-01

183

Genetic diversity associated with in vitro and conventional bud propagation of Saccharum varieties using RAPD analysis

Crosses between field isolates of Magnaporthe grisea (anamorph, Pyricularia oryzae Cav. and Pyricularia grisea) have led to the development of fertile laboratory strains that infect goosegrass and/or weeping lovegrass. These strains may now be utilized in a rigorous genetic analysis of host species specificity and general pathogenicity. Attempts to improve the fertility of rice pathogens for the goal of undertaking a genetic analysis of host cultivar specificity have so far been unsuccessful. Crosses between M. grisea strains that infect rice, goosegrass or weeping lovegrass demonstrate that host species specificity differences between field isolates of this fungus in some cases have a complete genetic basis, and in other cases have a simple genetic basis. Crosses between a field isolate of the pathogen that infects weeping lovegrass and a field isolate that infects goosegrass have resulted in the ...

1984-01-01

184

British Library Electronic Table of Contents (United Kingdom)

Abstract Polymorphisms in the genomic DNA of eight varieties maintained by conventional bud propagation (via rhizomes) and by in vitro shoot tip cultures were detected by RAPD analysis of sugarcane varieties. The study estimated the genetic diversity induced after in vitro multiplication of these varieties. Higher (28.9%) and lower (12%) numbers of polymorphic bands were detected in plants propagated via rhizomes; the genetic similarity estimate varying from 0.63 to 0.80. Plants of SP90-3723 and SP91-1049, or RB85-5113 and SP90-3723, varieties involving greater genetic distances may be indicated as progenitors in breeding programmes. In vitro multiplication of RB86-7515, RB85-5113, RB83-5054 and SP86-42 varieties increases genetic variability, while in vitro multiplication of SP91-1049, SP...

2008-01-01

185

Well-test data from geothermal reservoirs

Sex starved: do resource-limited males ensure fertilization success at the expense of precopulatory mating success?

Extensive well testing in geothermal resources has been carried out throughout the western United States and in northern Mexico since 1975. Each resource tested and each well test conducted by LBL during the eight-year period are covered in brief. The information, collected from published reports and memoranda, includes test particulars, special instrumentation, data interpretation when available, and plots of actual data. Brief geologic and hydrologic descriptions of the geothermal resources are also presented. The format is such that well test descriptions are grouped, in the order performed, into major sections according to resource, each section containing a short resource description followed by individual test details. Additional information regarding instrumentation is provided. Source documentation is provided throughout to facilitate access to further information and raw ...

1982-09-01

186

British Library Electronic Table of Contents (United Kingdom)

Theory predicts trade-offs between investment in various life history traits, and it is also now generally accepted that reproduction is costly for males. Males must therefore optimize resource allocation across several episodes of reproduction, and this includes investment in both pre- and postcopulatory fitness components. We investigated this in the sperm-polymorphic Indian meal moth, Plodia interpunctella. Resource-limited males were smaller, and had decreased precopulatory mating success, measured as lifetime number of matings. However, they transferred similar numbers of fertile sperm as males reared under high-quality larval conditions, and more nonfertile sperm. By mating less frequently, resource-limited males may allocate sufficient resources to the matings they achieve to ensure...

2011-01-01

187

Consumer demand for 'green power' and energy efficiency

Review of world hydrocarbon resource assessments. Final report. [1945 to 1980

This article examines reported willingness to pay for electric utility investments in renewable energy and energy efficiency resources using the results of Deliberative Polls conducted by electric utilities in Texas. Age, education, and salary tend to affect reported willingness to pay for utility investments in these resources. Intensive exposure to information about energy resource issues led to an increase in the number of respondents interested in paying a modest premium to support investments in both renewable energy resources and energy efficiency. However, average reported premiums actually declined following the Polls, as very high outlier responses moved to more reasonable values following the Polls. These results support the contention that informed dialogue about energy alternatives will result in broader interest in providing a modest level of support for these ...

2003-12-01

188

Oil shale resonances of the Green River formation in the northeastern part of the Green River Basin, Wyoming

This study reviews past assessments of world oil, natural gas, and oil-shale resources. It identifies the methods used in making these assessments (historical statistics, geological analogy, engineering, and probabilistic), the geographical coverage, the time horizons, and the major assumptions about such factors as discovery rates, and recovery factor. The period covered extends from the end of World War II to the end of 1980. Conclusions are presented on the current state of knowledge and understanding concerning each of these three hydrocarbon resources. Regarding world oil resources, an assumed consensus on 2000 billion barrels ultimately recoverable is, in fact, only weakly supported. Close examination of its component parts reveals widespread disagreement. World natural gas resources are even less well understood. And it is premature to venture a meaningful assessment of world oil-shale ...

1982-11-01

189

Analyses of mixed-hydrocarbon binary thermodynamic cycles for moderate-temperature geothermal resources

Oil shale resource data are provided for a 1300-square mile area around Farson, Wyoming. The data were derived from analyses of samples from 14 core holes drilled by the US Bureau of Mines and the Department of Energy, plus 4 core holes drilled by private companies. Fischer assay oil yield data for nine stratigraphic resource units are tabulated, correlated, and contoured to provide an assessment of shale oil potential in the area. Oil shale resources in the northeastern part of the Green River Basin occur in the Laney Member and the upper part of the Wilkins Peak Member of the Eocene Green River Formation. A total in-place shale oil resource of 137 billion barrels was calculated for the area. Four stratigraphic resource units have average oil yields of 12 to 20+ gallons per ton within the area of investigation, and in some parts a section up to 275 feet thick averages as much as ...

1988-03-01

190

What is the heritable component of spinal deformities in the European sea bass (Dicentrarchus labrax)?

A number of binary geothermal cycles utilizing mixed hydrocarbon working fluids were analyzed with the overall objective of finding a working fluid which can produce low-cost electrical energy using a moderately-low temperature geothermal resource. Both boiling and supercritical shell-and-tube cycles were considered. The performance of a dual-boiling isobutane cycle supplied by a 280/sup 0/F hydrothermal resource (corresponding to the 5 MW pilot plant at the Raft River site in Idaho) was selected as a reference. To investigate the effect of resource temperature on the choice of working fluid, several analyses were conducted for a 360/sup 0/F hydrothermal resource, which is representative of the Heber resource in California. The hydrocarbon working fluids analyzed included methane, ethane, propane, isobutane, isopentane, hexane, heptane, and mixtures of those pure hydrocarbons. For ...

1981-02-01

191

British Library Electronic Table of Contents (United Kingdom)

Malformations in farmed fish are a prime research topic as it has a major impact on fish welfare and on the economical value of the product. In this study, the genetic component of spine deformities was estimated in European sea bass, a major species of Mediterranean aquaculture, with the use of a posteriori reconstruction of pedigree with microsatellites. Our population exhibited a very high malformation rate (81%), probably due to intense swimming of fish during pre-growing. The heritability of global spine deformities was evaluated to be 0.21?0.04 on the underlying scale (0.33?0.06 for lordosis, 0.13?0.04 for scoliosis). Deformities scored by an internal or external examination turned out to be genetically the same trait (genetic correlations>0.9), although phenotypic correlations were ...

2009-01-01

192

The ribosome and the mechanism of protein synthesis

Summary of the OA biomarkers workshop 2010 - genetics and genomics: new targets in OA

In virtually all forms of life on earth, proteins in each cell are made according to a genetic blueprint, in the form of DNA. The translation of copies of this genetic blueprint (in the form of messenger RNA) into polypeptides is performed on the ribosome, a highly complex molecular machine composed of RNAs and proteins. To this end, special adaptor molecules called transfer RNAs are lined up by the ribosome in the sequence dictated by the genetic code, such that the amino acids carried by these molecules can be linked into a polypeptide. Several cofactors are involved in these processes, some of which require energy freed up by GTP hydrolysis. Although the ribosome was discovered more than 50 years ago, its structure has only been solved recently by X-ray crystallography. Another technique, cryo-electron microscopy, is starting to contribute toward our understanding of the ribosome's function, by portraying its ...

2006-05-01

193

British Library Electronic Table of Contents (United Kingdom)

On November fourth and fifth 2010 a group of more than 100 international investigators gathered in Atlanta for the second Osteoarthritis (OA) Biomarkers Global Initiative workshop titled ''Genetics and Genomics: New Targets in OA''. The first workshop took place in April 2009 and focused on in vitro (soluble) biomarkers whilst the third and final workshop will take place in 2012 and will focus on imaging biomarkers. The OA Research Society International (OARSI) has organized the workshops. In addition to OARSI, the National Institute of Arthritis, Musculoskeletal and Skin Diseases, the Arthritis Foundation, Amgen, Genzyme, the American Orthopaedic Society for Sports Medicine and Pfizer sponsored the second meeting. It was clear from this meeting that experiments in the genetics, epigenetic...

2011-01-01

194

Predicting the subspecific identity of invasive species using distribution models: Acacia saligna as an example

British Library Electronic Table of Contents (United Kingdom)

Abstract Aim- To explore whether the subspecific genetic entities of Acacia saligna occupy different bioclimatic niches in their native and introduced ranges and whether these niches are predictable using species distribution models (SDMs). Location- Australia, South Africa and the Mediterranean Basin. Methods- Species distribution models were developed in MAXENT using six climatic variables to calculate the climatic suitability of the ranges of A.saligna. We assessed (1) the subspecific niche differences identified by SDMs using measures of niche overlap and model performance; (2) the ability of SDMs to predict the most likely subspecific genetic entities present in South Africa based on comparisons to genetic data; and (3) the ability of SDMs to predict the most likely subspecific geneti...

2011-01-01

195

Molecular phylogeography of the microturbellarian Monocelis lineata (Platyhelminthes: Proseriata) in the North-East Atlantic

British Library Electronic Table of Contents (United Kingdom)

Monocelis lineata is a complex of cryptic species (three in the Mediterranean and one in the Atlantic) widespread in midlittoral habitats. Throughout the range, populations with or without an ocular pigmented shield are found. We investigated the genetic structure of the North-East Atlantic populations with the aim of shedding light on their phylogeography and reconstructing possible patterns of recolonization after the Wrmian glaciation. Fourteen samples were investigated using cytochrome c oxidase subunit I (COI) and 13 by inter-simple sequence repeats (ISSRs). COI did not exhibit a clear pattern of decreased genetic diversity along a latitudinal gradient. Populations from Ferrol (Spain), Doolin (Ireland), and Helsingr (Denmark) showed a higher genetic variability, whereas a reduction in...

2011-01-01

196

Human cDNA mapping using fluorescence in situ hybridization

Genetic fidelity of long-term micropropagated shoot cultures of vanilla (Vanilla planifolia Andrews) as assessed by molecular markers

Genetic mapping is approached using the techniques of high resolution fluorescence in situ hybridization (FISH). This technology and the results of its application are designed to rapidly generate whole genome as tool box of expressed sequence to speed the identification of human disease genes. The results of this study are intended to dovetail with and to link the results of existing technologies for creating backbone YAC and genetic maps. In the first eight months, this approach generated 60--80% of the expressed sequence map, the remainder expected to be derived through more long-term, labor-intensive, regional chromosomal gene searches or sequencing. The laboratory has made significant progress in the set-up phase, in mapping fetal and adult brain and other cDNAs, in testing a model system for directly linking genetic and physical maps using FISH with small fragments, in setting up a database, and in establishing the ...

1993-03-04

197

British Library Electronic Table of Contents (United Kingdom)

Occurrence of genetic variants during micropropagation is occasionally encountered when the cultures are maintained in vitro for long period. Therefore, the micropropagated multiple shoots of Vanilla planifolia Andrews developed from axillary bud explants established 10 years ago were used to determine somaclonal variation using random amplified polymorphic DNA (RAPD) and intersimple sequence repeats markers (ISSR). One thousand micro-plants were established in soil of which 95 plantlets (consisting of four phenotypes) along with the mother plant were subjected to genetic analyses using RAPD and ISSR markers. Out of the 45 RAPD and 20 ISSR primers screened, 30 RAPD and 7 ISSR primers showed 317 clear, distinct and reproducible band classes resulting in a total of 30 115 bands. However, no ...

2007-01-01

198

Genetic factors for resistance to diet-induced obesity and associated metabolic traits on mouse chromosome 17

British Library Electronic Table of Contents (United Kingdom)

Obesity is associated with increased susceptibility to dyslipidemia, insulin resistance, and hypertension, a combination of traits that comprise the traditional definition of the metabolic syndrome. Recent evidence suggests that obesity is also associated with the development of nonalcoholic fatty liver disease (NAFLD). Despite the high prevalence of obesity and its related conditions, their etiologies and pathophysiology remains unknown. Both genetic and environmental factors contribute to the development of obesity and NAFLD. Previous genetic analysis of high-fat, diet-induced obesity in C57BL/6J (B6) and A/J male mice using a panel of B6-ChrA/J/NaJ chromosome substitution strains (CSSs) demonstrated that 17 CSSs conferred resistance to high-fat, diet-induced obesity. One of these CSS st...

2009-01-01

199

Genetic and environmental interactions determine plant defences against herbivores

British Library Electronic Table of Contents (United Kingdom)

Summary 1. Plants express multiple defensive traits, but little is known about the genetic stability and phenotypic plasticity of these traits in nature. To investigate sources of variation and their potential ecological consequences for herbivores, we combined field observations of cyanogenic lima bean with laboratory experiments. 2. Field studies in South Mexico revealed a distinct variability of cyanogenic traits within and among wild lima bean populations. To differentiate among genetic variation and the impact of ambient conditions on plant phenotypes, we used seed grown plants as well as clones propagated from high (HC) and low cyanogenic (LC) wild type plants. 3. In growth chamber experiments, we cultivated plants under three intensities each of drought and salt stress, nutrient sup...

2011-01-01

200

Genetic Variation of Lodgepole Pine, Pinus contorta var. latifolia, Chemical and Physical Defenses that Affect Mountain Pine Beetle, Dendroctonus ponderosae, Attack and Tree Mortality

British Library Electronic Table of Contents (United Kingdom)

Plant secondary chemistry is determined by both genetic and environmental factors, and while large intraspecific variation in secondary chemistry has been reported frequently, the levels of genetic variation of many secondary metabolites in forest trees in the context of potential resistance against pests have been rarely investigated. We examined the effect of tree genotype and environment/site on the variation in defensive secondary chemistry of lodgepole pine, Pinus contorta var. latifolia, against the fungus, Grosmannia clavigera (formerly known as Ophiostoma clavigerum), associated with the mountain pine beetle, Dendroctonus ponderosae. Terpenoids were analyzed in phloem samples from 887, 20-yr-old trees originating from 45 half-sibling families planted at two sites. Samples were coll...

2011-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

201

Estimates of quantitative genetic parameters of immunological traits in the chicken.

Borderline personality traits and adult attention-deficit hyperactivity disorder symptoms: A genetic analysis of comorbidity

Three in vivo assays were used to measure the immunocompetence of chickens in two generations of a selection experiment. The obtained data were used to estimate the variance components for sire and dam for antibody production to Pasteurella multocida and Mycoplasma gallisepticum vaccines, for T-cell-mediated immunity evaluated by a phytohemagglutinin wing web assay, and for clearance of foreign particles from the circulatory system. Heritabilities of and genetic correlations among these immunological traits were calculated from the sire variance components. Heritability estimates of the immunological traits based on the sire component of variance ranged from .06 to .53, and genetic correlations among immunological traits were generally negative. PMID:1956847

1991-10-01

202

British Library Electronic Table of Contents (United Kingdom)

Abstract Previous research has established the comorbidity of adult Attention-Deficit Hyperactivity Disorder (ADHD) with different personality disorders including Borderline Personality Disorder (BPD). The association between adult ADHD and BPD has primarily been investigated at the phenotypic level and not yet at the genetic level. The present study investigates the genetic and environmental contributions to the association between borderline personality traits (BPT) and ADHD symptoms in a sample of 7,233 twins and siblings (aged 18-90 years) registered with the Netherlands Twin Register and the East Flanders Prospective Twin Survey (EFPTS) . Participants completed the Conners' Adult ADHD Rating Scales (CAARS-S:SV) and the Personality Assessment Inventory-Borderline Features Scale (PAI-BO...

2011-01-01

203

Association between chemical and genetic variation in Calophyllum inophyllum, a medicinally important tree of the Western Ghats of India

British Library Electronic Table of Contents (United Kingdom)

The objective of the present work is to study the chemical variation in Calophyllum inophyllum growing along the Western Ghats of India. Contents of dipyranocoumarins (inophyllums) in C.?inophyllum were determined to assess whether they could be used as a taxonomic marker for C.?inophyllum. This study also aims to establish inter simple sequence repeat (ISSR) markers that can be used to study genetic variation within the species and explore correlation between ISSR and chemical markers. The contents of dipyranocoumarins were estimated in seeds collected from 20 locations. Leaves from plants at the same 20 locations were assayed for ISSR variation. A dendrogram based on Nei?s genetic distance as well as principal component analysis based on dipyranocoumarins and ISSR variation clustered pla...

2011-01-01

204

An integrated genome research network for studying the genetics of alcohol addiction

British Library Electronic Table of Contents (United Kingdom)

Abstract Alcohol drinking is highly prevalent in many cultures and contributes to the global burden of disease. In fact, it was shown that alcohol constitutes 3.2% of all worldwide deaths in the year 2006 and is linked to more than 60 diseases, including cancers, cardiovascular diseases, liver cirrhosis, neuropsychiatric disorders, injuries and foetal alcohol syndrome. Alcoholism, which has been proven to have a high genetic load, is one potentially fatal consequence of chronic heavy alcohol consumption, and may be regarded as one of the most prevalent neuropsychiatric diseases afflicting our society today. The aim of the integrated genome research network -Genetics of Alcohol Addiction--which is a German inter-/trans-disciplinary life science consortium consisting of molecular biologists,...

2010-01-01

205

Natural resource valuation: A primer on concepts and techniques

Development of a methodology to assess the climate evolution and its impacts on wind energy

Natural resource valuation has always had a fundamental role in the practice of cost-benefit analysis of health, safety, and environmental issues. Today, this role is becoming all the more apparent in the conduct of natural resource damage assessments (NRDA) and cost-benefit analyses of environmental restoration (ER) and waste management (WM) activities. As such, environmental professionals are more interested in how natural resource values are affected by ER and WM activities. This professional interest extends to the use of NRDA values as measures of liability and legal causes of action under such environmental status as the Clean Water Act (CWA); the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA, as amended); and the Oil Pollution Act (OPA) of 1990. Also, environmental professionals are paying closer attention to NRDA values in cost-benefit analyses of risk and pollution-abatement ...

1997-07-01

206

solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database

Maps of wind resources were used to develop a method of evaluating climatic changes and their potential impacts on wind energy resources. Global IPCC climate change scenarios were used to predict climatic conditions for the future, while past wind resource availability was simulated and validated using NCEP and NCAR reanalysis data as well as observed meteorological data from Environment Canada. The simulations were used to compare each 5-year period with a 50-year reference period. Regional scale climate change impacts were evaluated using a statistical dynamic down-scaling method. Advanced meteorological models were used to predict wind flow patterns across specific landscapes. The evolution of past wind resource availability was then simulated. Five-year wind resource simulations for a 50-year period were simulated at 25 km"2 wind speeds at 80 m above the ground. Average wind ...

2010-11-01

207

Why is it getting more difficult to successfully artificially inseminate dairy cows?*

BackgroundA common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs requires...Full Text Available

208

Variation in Nicotine Consumption in Inbred Mice Is Not Linked to Orosensory Ability

Successfully using artificial insemination (AI) is defined as getting cows pregnant when the farmer wants them in-calf and making the best use of appropriate genetic potential. Over the past...Full Text Available

2008-08-01

209

Variable Pathogenicity Determines Individual Lifespan in Caenorhabditis elegans

Genetic studies of nicotine addiction in mice have utilized the oral self-administration model. However, it is unclear if strain differences in nicotine consumption are influenced by variation in bitter...Full Text Available

2009-01-01

210

Type I Collagen Is a Genetic Modifier of Matrix Metalloproteinase 2 in Murine Skeletal Development

A common property of aging in all animals is that chronologically and genetically identical individuals age at different rates. To unveil mechanisms that influence aging variability, we identified markers...Full Text Available

2011-04-01

211

Tumour-stromal interactions: Phenotypic and genetic alterations in mammary stroma - implications for tumour progression

Recessive inactivating mutations in human matrix metalloproteinase 2 (MMP2, gelatinase A) are associated with syndromes that include abnormal facial appearance, short stature, and severe bone...Full Text Available

2007-06-01

212

Transposable elements in fish functional genomics: technical challenges and perspectives

In addition to the well documented role of cytokines in mediating tissue-level interactions, it is now clear that matrix macromolecules fulfil a complementary regulatory function. Data highlighted in...Full Text Available

2001-01-01

213

Transgenesis in Xenopus using the Sleeping Beauty transposon system

The recent introduction of several transposable elements in zebrafish opens new frontiers for genetic manipulation in this important vertebrate model. This review discusses transposable elements as...Full Text Available

2007-01-01

214

The high Andes, gene flow and a stable hybrid zone shape the genetic structure of a wide-ranging South American parrot

Transposon-based integration systems have been widely used for genetic manipulation of invertebrate and plant model systems. In the past decade, these powerful tools have begun to be used in...Full Text Available

2009-07-01

215

The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN study*

BackgroundWhile the gene flow in some organisms is strongly affected by physical barriers and geographical distance, other highly mobile species are able to overcome such constraints....Full Text Available

216

The Spectrum of Monogenic Autoinflammatory Syndromes: Understanding Disease Mechanisms and Use of Targeted Therapies

Chronically elevated interleukin-6 (IL-6) affects lipid and lipoprotein metabolism. Individuals genetically predisposed to higher IL-6 secretion may be at risk of dyslipidemia, especially during the...Full Text Available

2008-08-01

217

The Sorcerer II Global Ocean Sampling Expedition: Northwest Atlantic through Eastern Tropical Pacific

Monogenic autoinflammatory diseases encompass a distinct and growing clinical entity of multisystem inflammatory diseases with known genetic defects in the innate immune system. The diseases...Full Text Available

2008-07-01

218

The Genetic Basis of Cellular Morphogenesis in the Filamentous Fungus Neurospora crassa

The world's oceans contain a complex mixture of micro-organisms that are for the most part, uncharacterized both genetically and biochemically. We report here a metagenomic study of the marine planktonic...Full Text Available

2007-03-01

219

The Dystrophin Complex Controls BK Channel Localization and Muscle Activity in Caenorhabditis elegans

Cellular polarity is a fundamental property of every cell. Due to their extremely fast growth rate (≥1 μm/s) and their highly elongated form, filamentous fungi represent a prime example...Full Text Available

2003-11-01

220

Temperature regulates limb length in homeotherms by directly modulating cartilage growth

Genetic defects in the dystrophin-associated protein complex (DAPC) are responsible for a variety of pathological conditions including muscular dystrophy, cardiomyopathy, and vasospasm. Conserved DAPC...Full Text Available

2009-12-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

221

Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase

Allen's Rule documents a century-old biological observation that strong positive correlations exist among latitude, ambient temperature, and limb length in mammals. Although genetic selection for thermoregulatory...Full Text Available

2008-12-09

222

Stressed-Induced TMEM135 Protein Is Part of a Conserved Genetic Network Involved in Fat Storage and Longevity Regulation in Caenorhabditis elegans

The development of new methods for gene addition to mammalian genomes is necessary to overcome the limitations of conventional genetic engineering strategies. Although a variety of DNA-modifying enzymes...Full Text Available

2011-09-01

223

Specific genetic modifications of domestic animals by gene targeting and animal cloning

Disorders of mitochondrial fat metabolism lead to sudden death in infants and children. Although survival is possible, the underlying molecular mechanisms which enable this outcome have not yet been...Full Text Available

224

Speciation genetics: current status and evolving approaches

The technology of gene targeting through homologous recombination has been extremely useful for elucidating gene functions in mice. The application of this technology was thought impossible in the large...Full Text Available

225

Soluble Epoxide Hydrolase Inhibition: Targeting Multiple Mechanisms of Ischemic Brain Injury with a Single Agent

The view of species as entities subjected to natural selection and amenable to change put forth by Charles Darwin and Alfred Wallace laid the conceptual foundation for understanding speciation. Initially...Full Text Available

2010-06-12

226

Single nucleotide polymorphisms for assessing genetic diversity in castor bean (Ricinus communis)

SummarySoluble epoxide hydrolase (sEH) is a key enzyme in the metabolic conversion and degradation of P450 eicosanoids called epoxyeicosatrienoic acids (EETs). Genetic variations...Full Text Available

2009-03-01

227

Sexual differentiation of the zebra finch song system: potential roles for sex chromosome genes

BackgroundCastor bean (Ricinus communis) is an agricultural crop and garden ornamental that is widely cultivated and has been introduced worldwide. Understanding...Full Text Available

228

Sex modifies exercise and cardiac adaptation in mice

BackgroundRecent evidence suggests that some sex differences in brain and behavior might result from direct genetic effects, and not solely the result of the organizational effects...Full Text Available

229

Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts

How an individual’s sex and genetic background modify cardiac adaptation to increased workload is a topic of great interest. We systematically evaluated morphological and physiological...Full Text Available

2004-12-01

230

Although genetically identical for autosomal Chrs (Chr), male and female preimplantation embryos could display sex-specific transcriptional regulation. To illustrate sex-specific differences at the...Full Text Available

2010-02-23

231

STR References 3001-3250

Root Suberin Forms an Extracellular Barrier That Affects Water Relations and Mineral Nutrition in Arabidopsis

Journal of Human Genetics. 82: 873-882. 3134. Schulz, I., Schneider, P. M., Olek, K, Rothschild, M. A., and Tsokos, M. (2006) Examination of Postmortem Animal Interference to Human...

2009-03-16

232

Role of the nac gene product in the nitrogen regulation of some NTR-regulated operons of Klebsiella aerogenes.

Though central to our understanding of how roots perform their vital function of scavenging water and solutes from the soil, no direct genetic evidence currently exists to support the foundational model...Full Text Available

2009-05-01

233

A positive, genetic selection against the activity of the nitrogen regulatory (NTR) system was used to isolate insertion mutations affecting nitrogen regulation in Klebsiella aerogenes. Two classes...Full Text Available

1990-12-01

234

Research - Keyword Index

Remobilization of Tol2 transposons in Xenopus tropicalis

...and biological processes acting on recruitment and post-recruitment EU-Agrinet - Project sheet: Biological performance testing methodology to evaluate the durability of plywood as a quality indicator ... Project sheet: Biological performance testing methodology to evaluate the durability of plywood as a quali EU-Agrinet - Project sheet: Genetic evaluation of European ...

235

Relationship between mRNA secondary structure and sequence variability in Chloroplast genes: possible life history implications

BackgroundThe Class II DNA transposons are mobile genetic elements that move DNA sequence from one position in the genome to another. We have previously demonstrated that the naturally...Full Text Available

236

Regulation of G1 Cell Cycle Progression

BackgroundSynonymous sites are freer to vary because of redundancy in genetic code. Messenger RNA secondary structure restricts this freedom, as revealed by previous findings in...Full Text Available

237

Recovery of Pathogenic Measles Virus from Cloned cDNA

Most genetic changes that promote tumorigenesis involve dysregulation of G1 cell cycle progression. A key regulatory site in G1 is a growth factor–dependent restriction point (R) where cells...Full Text Available

2010-11-01

238

Reconstructing Mammalian Phylogenies: A Detailed Comparison of the Cytochrome b and Cytochrome Oxidase Subunit I Mitochondrial Genes

Reverse genetics technology so far established for measles virus (MeV) is based on the Edmonston strain, which was isolated several decades ago, has been passaged in nonlymphoid cell lines, and is no...Full Text Available

2000-07-01

239

Rapid in vivo transport and catabolism of human apolipoprotein A-IV-1 and slower catabolism of the apoA-IV-2 isoprotein.

The phylogeny and taxonomy of mammalian species were originally based upon shared or derived morphological characteristics. However, genetic analyses have more recently played an increasingly important...Full Text Available

240

Radiation exposure due to X-rays of the hip joint in babies

Apolipoprotein (apo) A-IV is a polymorphic, intestinally derived apolipoprotein that is genetically linked to and similar in structure to apoA-I, the major apolipoprotein in high density lipoproteins...Full Text Available

1993-08-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

241

QSAR Studies of Copper Azamacrocycles and Thiosemicarbazones

Exact anatomic knowledge about the location of the gonads and the application of corresponding measures of radiation protection are the preconditions for an efficient reduction of the danger of a possible genetic damage as a result of radiation exposition during X-ray examination of the hip joint of newborns. (VJ).

242

Public interest in predictive genetic testing, including direct-to-consumer testing, for susceptibility to major depression: preliminary findings

Genetic algorithms (GA) were used to develop specific copper metal-ligand force field parameters for the MM3 force field, from a combination of crystallographic structures and ab initio...Full Text Available

2005-08-25

243

Programmed Cell Death during Pollination-Induced Petal Senescence in Petunia1

The past decade has seen rapid advances in the identification of associations between candidate genes and a range of common multifactorial disorders. This paper evaluates public attitudes towards the...Full Text Available

2010-01-01

244

Power of grammatical evolution neural networks to detect gene-gene interactions in the presence of error

Petal senescence, one type of programmed cell death (PCD) in plants, is a genetically controlled sequence of events comprising its final developmental stage. We characterized the pollination-induced...Full Text Available

2000-04-01

245

Population genetic analysis of large sequence polymorphisms in Plasmodium falciparum blood-stage antigens

BackgroundWith the advent of increasingly efficient means to obtain genetic information, a great insurgence of data has resulted, leading to the need for methods for analyzing this...Full Text Available

246

Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study

Plasmodium falciparum, the causative agent of human malaria, invades host erythrocytes using several proteins on the surface of the invasive merozoite, which have been proposed...Full Text Available

2010-03-01

247

Phylometabonomic Patterns of Adaptation to High Fat Diet Feeding in Inbred Mice

Human longevity is in part genetically determined, and the insulin/IGF-1 signal transduction (IIS) pathway has consistently been implicated. In humans, type 2 diabetes is a frequent disease that results...Full Text Available

248

Phylogenetic Network for European mtDNA

Insulin resistance plays a central role in type 2 diabetes and obesity, which develop as a consequence of genetic and environmental factors. Dietary changes including high fat diet (HFD) feeding promotes...Full Text Available

249

Persistent Staphylococcus aureus Colonization Is Not a Strongly Heritable Trait in Amish Families

The sequence in the first hypervariable segment (HVS-I) of the control region has been used as a source of evolutionary information in most phylogenetic analyses of mtDNA. Population genetic inference...Full Text Available

2001-06-01

250

Pathophysiological, Genetic and Gene Expression Features of a Novel Rodent Model of the Cardio-Metabolic Syndrome

About 20% of adults are persistently colonized with S. aureus in the anterior nares. Host genetic factors could contribute susceptibility to this phenotype. The objective of...Full Text Available

251

Parent-of-origin effects on voluntary exercise levels and body composition in mice

BackgroundComplex etiology and pathogenesis of pathophysiological components of the cardio-metabolic syndrome have been demonstrated in humans and animal models.Methodology/Principal...Full Text Available

252

PKU is a reversible neurodegenerative process within the nigrostriatum that begins as early as 4 weeks of age in Pah^enu2 mice

Despite the health-related benefits of exercise, many people do not engage in enough activity to realize the rewards, and little is known regarding the genetic or environmental components that account...Full Text Available

2010-01-01

253

Olfactory copy number association with age at onset of Alzheimer disease

Phenylketonuria (PKU) is a common genetic disorder in humans that arises from deficient activity of phenylalanine hydroxylase (PAH), which catalyzes the conversion of phenylalanine to tyrosine....Full Text Available

2007-01-05

254

Oil palm (Elaeis guineensis Jacq.) tissue culture ESTs: Identifying genes associated with callogenesis and embryogenesis

Objectives:Copy number variants (CNVs) have been recognized as a source of genetic variation that contributes to disease phenotypes. Alzheimer disease (AD) has high heritability...Full Text Available

2011-04-12

255

Nuclear reprogramming in mammalian somatic cell nuclear cloning

BackgroundOil palm (Elaeis guineensis Jacq.) is one of the most important oil bearing crops in the world. However, genetic improvement of oil palm through conventional...Full Text Available

256

Nuclear Receptor Rev-erb Alpha (Nr1d1) Functions in Concert with Nr2e3 to Regulate Transcriptional Networks in the Retina

Nuclear cloning is still a developing technique used to create genetically identical animals by somatic cell nuclear transfer into unfertilized eggs. Despite an intensive effort in a number...Full Text Available

2004-01-01

257

Novel Multilocus Measure of Linkage Disequilibrium to Estimate Past Effective Population Size

The majority of diseases in the retina are caused by genetic mutations affecting the development and function of photoreceptor cells. The transcriptional networks directing these processes are regulated...Full Text Available

258

Myofibrillogenesis in the developing zebrafish heart: A functional study of tnnt2

Linkage disequilibrium (LD) between densely spaced, polymorphic genetic markers in humans and other species contains information about historical population size. Inferring past population size is of...Full Text Available

2003-04-01

259

Mycolic Acid Analysis by High-Performance Liquid Chromatography for Identification of Mycobacterium Species

Various hypotheses have been proposed to explain the molecule processes of sarcomere assembly, partially due to the lack of systematic genetic studies of sarcomeric genes in an in vivo...Full Text Available

2009-07-15

260

Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins.

Mycobacterium tuberculosis is the etiologic agent of tuberculosis and can be accurately detected by laboratories using commercial genetic tests. Nontuberculosis mycobacteria (NTM) causing other mycobacterioses...Full Text Available

2001-10-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

261

Mutation analysis of 272 Spanish families affected by autosomal recessive retinitis pigmentosa using a genotyping microarray

In our quest for novel genes required for the development of the embryonic peripheral nervous system (PNS), we have performed three genetic screens using MAb 22C10 as a marker of terminally differentiated...Full Text Available

2000-12-01

262

Multivariate analyses reveal common and drug specific genetic influences on responses to four drugs of abuse

PurposeRetinitis pigmentosa (RP) is a genetically heterogeneous disorder characterized by progressive loss of vision. The aim of this study was to identify the causative mutations...Full Text Available

263

Molecular mechanisms of genetic adaptation to xenobiotic compounds.

Vulnerability to abused drugs is influenced by multiple genes unique to each drug as well as to risk genes for polydrug abuse. If several inbred mouse strains respond to different drugs similarly,...Full Text Available

2008-11-01

264

Molecular biological enhancement of coal biodesulfurization. Final report, October 1988--December 1991

Microorganisms in the environment can often adapt to use xenobiotic chemicals as novel growth and energy substrates. Specialized enzyme systems and metabolic pathways for the degradation of man-made...Full Text Available

1992-12-01

265

Mobilizing diversity: transposable element insertions in genetic variation and disease

The overall objective of this project was to use molecular genetics to develop strains of bacteria with enhanced ability to remove sulfur from coal, and to obtain data that will allow the performance and economics of a coal biodesulfurization process to be predicted. (VC)

1991-12-01

266

Microsatellite-based genetic diversity and population structure of domestic sheep in northern Eurasia

Transposable elements (TEs) comprise a large fraction of mammalian genomes. A number of these elements are actively jumping in our genomes today. As a consequence, these insertions provide a source...Full Text Available

267

Mapping Quantitative Trait Loci Controlling Milk Production in Dairy Cattle by Exploiting Progeny Testing

BackgroundIdentification of global livestock diversity hotspots and their importance in diversity maintenance is essential for making global conservation efforts. We screened 52...Full Text Available

268

Mammalian life-span determinant p66^shcA mediates obesity-induced insulin resistance

We have exploited ``progeny testing'' to map quantitative trait loci (QTL) underlying the genetic variation of milk production in a selected dairy cattle population. A total of 1,518 sires, with progeny...Full Text Available

1995-02-01

269

Lymphocytes, neuropeptides, and genes involved in alopecia areata

Obesity and metabolic syndrome result from excess calorie intake and genetic predisposition and are mechanistically linked to type II diabetes and accelerated body aging; abnormal nutrient and insulin...Full Text Available

2010-07-27

270

Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies

Many lessons in autoimmunity — particularly relating to the role of immune privilege and the interplay between genetics and neuroimmunology — can be learned from the study of alopecia...Full Text Available

2007-08-01

271

Interpopulation hybridization results in widespread viability selection across the genome in Tigriopus californicus

Recently, genome-wide association studies (GWAS) have linked the human LIN28B locus to height and timing of menarche [1-Full Text Available

2010-07-01

272

Integrase-directed recovery of functional genes from genomic libraries

BackgroundGenetic interactions within hybrids influence their overall fitness. Understanding the details of these interactions can improve our understanding of speciation. One experimental...Full Text Available

273

Insecticidal properties of genetically engineered baculoviruses expressing an insect juvenile hormone esterase gene.

Large population sizes, rapid growth and 3.8 billion years of evolution firmly establish microorganisms as a major source of the planet's biological and genetic diversity. However, up to 99% of the...Full Text Available

2009-09-01

274

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

Exploring the possibility of enhancing the properties of baculoviruses as biological control agents of insect pests, we tested the effect of expressing an insect gene (jhe) encoding juvenile hormone...Full Text Available

1992-05-01

275

Inferring gene regulatory networks from asynchronous microarray data with AIRnet

As the result of genetic alterations and tumor hypoxia, many cancer cells avidly take up glucose and generate lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc...Full Text Available

2010-02-02

276

Infant Milk Feeding Influences Adult Bone Health: A Prospective Study from Birth to 32 Years

BackgroundModern approaches to treating genetic disorders, cancers and even epidemics rely on a detailed understanding of the underlying gene signaling network. Previous work has...Full Text Available

277

Increased Ethanol Productivity in Xylose-Utilizing Saccharomyces cerevisiae via a Randomly Mutagenized Xylose Reductase?

BackgroundPeak bone mass, attained by early adulthood, is influenced by genetic and life-style factors. Early infant feeding and duration of breastfeeding in particular, associate...Full Text Available

278

In Vivo RNAi Screening Identifies Regulators of Actin Dynamics as Key Determinants of Lymphoma Progression

Baker's yeast (Saccharomyces cerevisiae) has been genetically engineered to ferment the pentose sugar xylose present in lignocellulose biomass. One of the reactions controlling the...Full Text Available

2010-12-01

279

Improvement of Aroma in Transgenic Potato As a Consequence of Impairing Tuber Browning

Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic...Full Text Available

2009-10-01

280

Impaired replication dynamics at the FRA3B common fragile site

Sensory analysis studies are critical in the development of quality enhanced crops, and may be an important component in the public acceptance of genetically modified foods. It has recently been established...Full Text Available

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

281

Impact of genetic changes to the CRPV genome and their application to the study of pathogenesis in vivo

Chromosomal common fragile sites (CFSs) are genetically unstable regions of the genome that are induced by conditions that impair DNA replication. In this report, we show that treatment with the DNA...Full Text Available

2010-01-01

282

Immortalizing the Complexity of Cancer Metastasis Genetic Features of Lethal Metastatic Pancreatic Cancer Obtained from Rapid Autopsy

The cottontail rabbit papillomavirus (CRPV)/rabbit model has been used to study oncogenicity and immunogenicity of different antigens from the papillomavirus genome and has therefore served...Full Text Available

2007-02-20

283

Identification of genetic variation and haplotype structure of the canine ABCA4 gene for retinal disease association studies

The virtual lack of well-characterized metastatic pancreatic cancer tissues for study has limited systematic studies of the metastatic process of this deadly disease. To address this important...Full Text Available

2005-05-01

284

Identification of genes and haplotypes that predict rheumatoid arthritis using random forests

Over 200 mutations in the retina specific member of the ATP-binding cassette transporter super-family (ABCA4) have been associated with a diverse group of human retinal diseases....Full Text Available

2010-10-01

285

Identification of a Copper-Responsive Two-Component System on the Chromosome of Escherichia coli K-12

Random forest (RF) analysis of genetic data does not require specification of the mode of inheritance, and provides measures of variable importance that incorporate interaction effects. In this paper...Full Text Available

286

Ichthyosis follicularis, alopecia, and photophobia (IFAP) syndrome

Using a genetic screen we have identified two chromosomal genes, cusRS (ylcA ybcZ), from Escherichia coli K-12 that encode a two-component, signal...Full Text Available

2000-10-01

287

ICC-MY coordinate smooth muscle electrical and mechanical activity in the murine small intestine

The IFAP syndrome is a rare X-linked genetic disorder reported in nearly 40 patients. It is characterized by the triad of Ichthyosis Follicularis, Alopecia, and Photophobia from birth. Other features...Full Text Available

288

How DNA coiling enhances target localization by proteins

BackgroundAnimals carrying genetic mutations have provided powerful insights into the role of interstitial cells of Cajal (ICC) in motility. One classic model is...Full Text Available

2010-05-01

289

Highly lytic and persistent lentiviruses naturally present in sheep with progressive pneumonia are genetically distinct.

Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly. After initial...Full Text Available

2008-10-14

290

High genetic variability and low local diversity in a population of arbuscular mycorrhizal fungi

Ovine and caprine lentiviruses share the capacity to induce slowly progressive and inflammatory diseases of the central nervous system (leukoencephalitis or visna), lungs (progressive pneumonia or maedi),...Full Text Available

1984-11-01

291

Heritability of Lumbar Trabecular Bone Mechanical Properties in Baboons

Arbuscular mycorrhizal fungi (AMF) are ecologically important root symbionts of most terrestrial plants. Ecological studies of AMF have concentrated on differences between species; largely assuming...Full Text Available

2004-02-24

292

Hereditary Connective Tissue Diseases in Young Adult Stroke: A Comprehensive Synthesis

Genetic effects on mechanical properties have been demonstrated in rodents, but not confirmed in primates. Our aim was to quantify the proportion of variation in vertebral trabecular bone mechanical...Full Text Available

2010-03-01

293

Gyrase B Inhibitor Impairs HIV-1 Replication by Targeting Hsp90 and the Capsid Protein*

Though the genetic background of ischaemic and haemorrhagic stroke is often polygenetic or multifactorial, it can in some cases result from a monogenic disease, particularly in young adults. Besides...Full Text Available

294

Genome-wide detection and characterization of positive selection in human populations

Chemical genetics is an emerging approach to investigate the biology of host-pathogen interactions. We screened several inhibitors of ATP-dependent DNA motors and detected the gyrase B inhibitor coumermycin...Full Text Available

2010-12-10

295

Genetics of the mammalian phenylalanine hydroxylase system. Studies of human liver phenylalanine hydroxylase subunit structure and of mutations in phenylketonuria.

With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms...Full Text Available

2007-10-18

296

Genetics and molecular pathology of Stargardt-like macular degeneration

Phenylalanine hydroxylase was purified from crude extracts of human livers which show enzyme activity by usine two different methods: (a) affinity chromatography and (b) immunoprecipitation with an...Full Text Available

1979-08-01

297

Genetic heterogeneity in human T-cell leukemia/lymphoma virus type II.

Stargardt-like macular degeneration (STGD3) is an early onset, autosomal dominant macular degeneration. STGD3 is characterized by a progressive pathology, the loss of central vision, atrophy...Full Text Available

2010-05-01

298

Genetic association between the COMT genotype and urinary levels of tea polyphenols and their metabolites among daily green tea drinkers

DNA from the peripheral blood mononuclear cells of 17 different individuals infected with human T-cell lymphoma/leukemia virus type II (HTLV-II) was successfully amplified by the polymerase chain reaction...Full Text Available

1993-03-01

299

Genetic architecture of voluntary exercise in an advanced intercross line of mice

Available in vitro and animal studies have shown cancer protective effects of tea polyphenols. Recent study suggests a greater protective effect of green tea intake on breast cancer...Full Text Available

300

Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans

Exercise is essential for health, yet the amount, duration, and intensity that individuals engage in are strikingly variable, even under prescription. Our focus was to identify the locations and effects...Full Text Available

2010-07-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

301

Genetic Variation at the Mitochondrial DNA 9-bp Repeat Locus in the Sakha of Siberia

Neurofibromatosis type 1 (NF1) results from mutations in the NF1 tumor suppressor gene, which encodes the protein neurofibromin. NF1 patients display diverse clinical manifestations,...Full Text Available

2010-03-01

302

Genetic Susceptibility for Individual Cooperation Preferences: The Role of Monoamine Oxidase A Gene (MAOA) in the Voluntary Provision of Public Goods

... 16223, 16292, and 16295, which classify them as haplogroup W (Richards et al. 2000). The sample that was ... belonged to haplogroup B, 2 individuals belonged to haplogroup W, and 1 individual belonged to ...

303

Genetic Polymorphism of Cancer Susceptibility Genes and HPV Infection in Cervical Carcinogenesis

In the context of social dilemmas, previous research has shown that human cooperation is mainly based on the social norm of conditional cooperation. While in most cases individuals behave according...Full Text Available

304

Genetic Modulation of GABA Levels in the Anterior Cingulate Cortex by GAD1 and COMT

It is widely accepted that specific human papillomavirus (HPV) types are the central etiologic agent of cervical carcinogenesis. However, a number of infected women do not develop invasive lesions,...Full Text Available

305

Genetic Heterogeneity in Severe Congenital Neutropenia: How Many Aberrant Pathways Can Kill a Neutrophil?

γ-Aminobutyric acid (GABA)-ergic transmission is critical for normal cortical function and is likely abnormal in a variety of neuropsychiatric disorders. We tested the in...Full Text Available

2010-07-01

306

Genetic Evidence for Inhibition of Bacterial Division Protein FtsZ by Berberine

Purpose of reviewSevere congenital neutropenia (SCN) is a primary immunodeficiency in which lack of neutrophils causes inadequate innate immune host response to bacterial...Full Text Available

2007-12-01

307

Genetic Diversity in Blastomyces dermatitidis: Implications for PCR Detection in Clinical and Environmental Samples

BackgroundBerberine is a plant alkaloid that is widely used as an anti-infective in traditional medicine. Escherichia coli exposed to berberine form filaments, suggesting...Full Text Available

308

Genetic Association Analysis of NOS1 and Methamphetamine-Induced Psychosis Among Japanese

SummaryBlastomycosis is a serious and potentially fatal infection by the thermally dimorphic fungus Blastomyces dermatitidis. PCR assays targeting the BAD-1 virulence...Full Text Available

2010-03-01

309

Genetic Analysis of Cytoprotective Functions Supported by Graded Expression of Keap1?

The neuronal nitric oxide synthase gene (NOS1) is located at 12q24, a susceptibility region for schizophrenia, and produces nitric oxide (NO). NO has been reported to play important...Full Text Available

2011-03-01

310

Genetic Ablation of NADPH Oxidase Enhances Susceptibility to Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice

Keap1 regulates Nrf2 activity in response to xenobiotic and oxidative stresses. Nrf2 is an essential regulator of cytoprotective genes. Keap1-null mice are lethal by weaning age due...Full Text Available

2010-06-01

311

Generation of Novel Bacterial Regulatory Proteins That Detect Priority Pollutant Phenols

Cigarette smoke (CS) induces recruitment of inflammatory cells in the lungs leading to the generation of reactive oxygen species (ROS), which are involved in lung inflammation and injury. Nicotinamide...Full Text Available

2008-05-01

312

Gene-gene and gene-environment interactions: new insights into the prevention, detection and management of coronary artery disease

The genetic systems of bacteria that have the ability to use organic pollutants as carbon and energy sources can be adapted to create bacterial biosensors for the detection of industrial pollution....Full Text Available

2000-01-01

313

Gene-Environment Interactions and Epigenetic Basis of Human Diseases

Despite the recent success of genome-wide association studies (GWASs) in identifying loci consistently associated with coronary artery disease (CAD), a large proportion of the genetic components of...Full Text Available

314

Frequent Promoter Hypermethylation of the APC and RASSF1A Tumour Suppressors in Parathyroid Tumours

Most human diseases are related in some way to the loss or gain in gene functions. Regulation of gene expression is a complex process. In addition to genetic mechanisms, epigenetic causes are...Full Text Available

2008-01-01

315

Familial occurrence of unilateral giant breasts in Nigeria: a possible new genetic entity.

BackgroundParathyroid adenomas constitute the most common entity in primary hyperparathyroidism, and although recent advances have been made regarding the underlying genetic cause...Full Text Available

316

Extracellular Administration of BCL2 Protein Reduces Apoptosis and Improves Survival in a Murine Model of Sepsis

Four cases of unilateral giant breasts from two unrelated families are described. Three of the patients were managed surgically. It is speculated from a review of available published reports that this...Full Text Available

1984-04-01

317

Expression Signatures of Metastatic Capacity in a Genetic Mouse Model of Lung Adenocarcinoma

BackgroundSevere sepsis and septic shock are major causes of morbidity and mortality worldwide. In experimental sepsis there is prominent apoptosis of various cell types, and genetic...Full Text Available

318

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

BackgroundNon-small cell lung cancer (NSCLC) is the foremost cause of cancer-related death in Western countries, which is due partly to the propensity of NSCLC cells to metastasize....Full Text Available

319

Estimation of effective population sizes from data on genetic markers

The incidence of melanoma is increasing more than any other cancer, and knowledge of its genetic alterations is limited. To systematically analyze such alterations, we performed whole-exome...Full Text Available

2011-05-01

320

Establishing the scientific and mechanistic framework for a GIN (Genetic Improvement Network)

The effective population size (N_e) is an important parameter in ecology, evolutionary biology and conservation biology. It is, however, notoriously difficult to estimate,...Full Text Available

2005-07-29

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

321

Environmental Research Database

Objectives7. (b) Objectives General background Livestock production accounts for 70% of the agricultural land on the planet. Given that demand for livestock products is expected to double by 2050 it is vital that we identify less polluting ways of production, spanning both intensive and extensive systems. Northern Europe is one of the few parts of the globe where climate change is expected to be neutral or even benefit agricultural productivity. Hence it is likely to make an even more important co [continued...]DescriptionRuminant genetic improvement can play an important role in developing livestock systems that will be sustainable in the future, and produce food in an environmentally friendly manner. Also, genetic improvement of livestock is a particularly cost-effective technology, producing permanent and cumulative changes in performance. Moran et al (2007) showed the very high value of animal and plant genetics ...

2010-01-31

322

Engineering of a psychrophilic bacterium for the bioremediation of aromatic compounds

Engineering ligand-responsive RNA controllers in yeast through the assembly of RNase III tuning modules

Microbial degradation of aromatic hydrocarbons has been studied with the aim of developing applications for the removal of toxic compounds. Efforts have been directed toward the genetic manipulation...Full Text Available

2010-05-01

323

Djinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration

The programming of cellular networks to achieve new biological functions depends on the development of genetic tools that link the presence of a molecular signal to gene-regulatory activity. Recently,...Full Text Available

2011-07-01

324

Dissecting the Genetic Components of Adaptation of Escherichia coli to the Mouse Gut

BackgroundThere is an ever increasing rate of data made available on genetic variation, transcriptomes and proteomes. Similarly, a growing variety of bioinformatic programs are becoming...Full Text Available

325

Differential effects of the mottled yellow and pseudoagouti phenotypes on immunocompetence in Avy/a mice.

While pleiotropic adaptive mutations are thought to be central for evolution, little is known on the downstream molecular effects allowing adaptation to complex ecologically relevant environments. Here...Full Text Available

2008-01-01

326

Development of an extrachromosomal cloning vector system for use in Borrelia burgdorferi

Whereas genetic factors are known to influence both susceptibility to carcinogens and the capacity to respond to specific antigenic stimuli, little is known regarding the influence of phenotype per...Full Text Available

1984-04-01

327

Detection of genetic mutations in repetitive DNA sequences in somatic human cells after low-dose irradiation; Nachweis genetischer Veraenderungen in repetitiven DNA-Sequenzen in somatischen menschlichen Zellen nach Bestrahlung im niedrigen Dosisbereich

Molecular genetic analysis of Borrelia burgdorferi, the cause of Lyme disease, has been hampered by the absence of any means of efficient generation, identification, and complementation...Full Text Available

2000-04-25

328

Detection and Identification of Ciprofloxacin-Resistant Yersinia pestis by Denaturing High-Performance Liquid Chromatography

No abstract prepared

1998-03-01

329

Destructive effects of smoking on molecular and genetic factors of periodontal disease

Denaturing high-performance liquid chromatography (DHPLC) has been used extensively to detect genetic variation. We used this method to detect and identify Yersinia pestis KIM5 ciprofloxacin-resistant...Full Text Available

2003-07-01

330

Design of 240,000 orthogonal 25mer DNA barcode probes

Many epidemiological evidences have proven the association between smoking and periodontal disease. The causality can be further established by linking findings of traditional epidemiological studies...Full Text Available

331

Deletion of the Receptor for Advanced Glycation End Products Reduces Glomerulosclerosis and Preserves Renal Function in the Diabetic OVE26 Mouse

DNA barcodes linked to genetic features greatly facilitate screening these features in pooled formats using microarray hybridization, and new tools are needed to design large sets of barcodes to allow...Full Text Available

2009-02-17

332

De Novo Induction of Genetically Engineered Brain Tumors In Mice Using Plasmid DNA

OBJECTIVEPrevious studies showed that genetic deletion or pharmacological blockade of the receptor for advanced glycation end products (RAGE) prevents the early structural changes...Full Text Available

2010-08-01

333

Cytogenetic analysis of three sea catfish species (Teleostei, Siluriformes, Ariidae) with the first report of Ag-NOR in this fish family

Spontaneous mouse models of cancer show promise to more accurately recapitulate human disease and predict clinical efficacy. Transgenic mice or viral vectors have been required to generate spontaneous...Full Text Available

2009-01-15

334

Contrasting Population Structures of the Genes Encoding Ten Leading Vaccine-Candidate Antigens of the Human Malaria Parasite, Plasmodium falciparum

Despite their ecological and economical importance, fishes of the family Ariidae are still genetically and cytogenetically poorly studied. Among the 133 known species of ariids, only eight have been...Full Text Available

2010-04-01

335

Construction of DNA recognition sites active in Haemophilus transformation.

The extensive diversity of Plasmodium falciparum antigens is a major obstacle to a broadly effective malaria vaccine but population genetics has rarely been used to guide vaccine design....Full Text Available

336

Construction and Characterization of Genetically Defined aro omp Mutants of Enterotoxigenic Escherichia coli and Preliminary Studies of Safety and Immunogenicity in Humans

Competent Haemophilus cells recognize and preferentially take up Haemophilus DNA during genetic transformation. This preferential uptake is correlated with the presence on incoming DNA of an 11-base-pair...Full Text Available

1982-04-01

337

Confocal microscopy for the analysis of siRNA delivery by polymeric nanoparticles

Enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea in travelers to countries where the disease is endemic and causes a major disease burden in the indigenous population,...Full Text Available

2001-08-01

338

Complex Integration of Matrix, Oxidative Stress, and Apoptosis in Genetic Emphysema

Clinical applications of genetic therapies, including delivery of short, interfering RNAs (siRNAs) for RNA interference (RNAi), are limited due to the difficulty of delivering nucleic acids...Full Text Available

2010-09-01

339

Completely phased genome sequencing through chromosome sorting

Alveolar enlargement, which is characteristic of bronchopulmonary dysplasia, congenital matrix disorders, and cigarette smoke-induced emphysema, is thought to result from enhanced inflammation and ensuing...Full Text Available

2009-07-01

340

Comparative mapping of Andropogoneae: Saccharum L. (sugarcane) and its relation to sorghum and?maize

The two haploid genome sequences that a person inherits from the two parents represent the most fundamentally useful type of genetic information for the study of heritable diseases and the development...Full Text Available

2011-01-04

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

341

Common mitochondrial polymorphisms as risk factor for endometrial cancer

Comparative genetic maps of Papuan Saccharum officinarum L. (2n = 80) and S. robustum (2n = 80) were constructed by using single-dose...Full Text Available

1997-12-23

342

Common Genetic Variants Associate with Serum Phosphorus Concentration

Endometrial carcinoma is the most commonly diagnosed gynaecological cancer in developed countries. Although the molecular genetics of this disease has been in the focus of many research laboratories...Full Text Available

343

Co-localization of Sorting Nexin 2 and Androgen Receptor in the Song System of Juvenile Zebra Finches

Phosphorus is an essential mineral that maintains cellular energy and mineralizes the skeleton. Because complex actions of ion transporters and regulatory hormones regulate serum phosphorus concentrations,...Full Text Available

2010-07-01

344

Climate Change, Genetics or Human Choice: Why Were the Shells of Mankind's Earliest Ornament Larger in the Pleistocene Than in the Holocene?

Mechanisms regulating sexual differentiation of the zebra finch song system appear to include both genetic and hormonal factors. Sorting Nexin 2 (SNX2), which is involved in trafficking proteins...Full Text Available

2010-07-09

345

Chemical complementation: A reaction-independent genetic assay for enzyme catalysis

BackgroundThe southern African tick shell, Nassarius kraussianus (Dunker, 1846), has been identified as being the earliest known ornamental object used by human...Full Text Available

346

Calcium, Vitamin D, VDR Genotypes, and Epigenetic and Genetic Changes in Rectal Tumors

A high-throughput assay for enzyme activity has been developed that is reaction independent. In this assay, a small-molecule yeast three-hybrid system is used to link enzyme catalysis to transcription...Full Text Available

2002-12-24

347

Biodiversity of Costa Rican salamanders: Implications of high levels of genetic differentiation and phylogeographic structure for species formation

Calcium, vitamin D, exposure to sunshine, and vitamin D receptor (VDR) genotypes have been associated rectal cancer. We used data from 750 rectal tumors and 1,205 population-based...Full Text Available

2010-05-01

348

Behavioral genomics of honeybee foraging and nest defense

Although salamanders are characteristic amphibians in Holarctic temperate habitats, in tropical regions they have diversified evolutionarily only in tropical America. An adaptive radiation centered...Full Text Available

2000-02-15

349

Association of COMT Val^108/158Met Genotype and Cigarette Smoking in Pregnant Women

The honeybee has been the most important insect species for study of social behavior. The recently released draft genomic sequence for the bee will accelerate honeybee behavioral genetics. Although...Full Text Available

2007-04-01

350

Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100.

Introduction:Smoking behaviors, including heaviness of smoking and smoking cessation, are known to be under a degree of genetic influence. The enzyme catechol O-methyltransferase...Full Text Available

2011-02-01

351

Assessment of the bone quality of black male athletes using calcaneal ultrasound: a cross-sectional study

Familial defective apolipoprotein (apo) B-100 is a genetic disease that leads to hypercholesterolemia and to an increased serum concentration of low density lipoproteins that bind defectively to the...Full Text Available

1989-01-01

352

Antidepressant-Like Effects of ?-Opioid Receptor Antagonists in Wistar Kyoto Rats

BackgroundLifestyle, genetics and environmental factors are established determinants of bone density. We aimed to describe the bone characteristics of competitive top-ranked Nigerian...Full Text Available

353

Anticipation in familial lattice corneal dystrophy type I with R124C mutation in the TGFBI (BIGH3) gene

The Wistar Kyoto (WKY) rat strain is a putative genetic model of comorbid depression and anxiety. Previous research showing increased κ-opioid receptor (KOR)...Full Text Available

2010-02-01

354

Angiotensin II Promotes Development of the Renal Microcirculation through AT₁ Receptors

PurposeTo report the clinical, ophthalmic, and genetic characteristics for lattice corneal dystrophy type I (LCDI) in a Chilean family.MethodsSix...Full Text Available

355

Analysis of non-TIR NBS-LRR resistance gene analogs in Musa acuminata Colla: Isolation, RFLP marker development, and physical mapping

Pharmacologic or genetic deletion of components of the renin-angiotensin system leads to postnatal kidney injury, but the roles of these components in kidney development are unknown. To test the hypothesis...Full Text Available

2010-03-01

356

Analysis of genomic differences among Clostridium botulinum type A1 strains

BackgroundMany commercial banana varieties lack sources of resistance to pests and diseases, as a consequence of sterility and narrow genetic background. Fertile wild relatives,...Full Text Available

357

An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer

BackgroundType A1 Clostridium botulinum strains are a group of Gram-positive, spore-forming anaerobic bacteria that produce a genetically, biochemically, and biophysically...Full Text Available

358

An excess of rare genetic variation in ABCE1 among Yorubans and African-American individuals with HIV-1

BackgroundGenomics has substantially changed our approach to cancer research. Gene expression profiling, for example, has been utilized to delineate subtypes of cancer, and facilitated...Full Text Available

359

An Immune Basis for Malaria Protection by the Sickle Cell Trait

Signatures of natural selection occur throughout the human genome and can be detected at the sequence level. We have re-sequenced ABCE1, a host candidate gene essential for...Full Text Available

2009-12-01

360

Air pollution induces heritable DNA mutations

BackgroundMalaria resistance by the sickle cell trait (genotype HbAS) has served as the prime example of genetic selection for over half a century. Nevertheless, the mechanism...Full Text Available

2005-05-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

361

Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network

Hundreds of thousands of people worldwide live or work in close proximity to steel mills. Integrated steel production generates chemical pollution containing compounds that can induce genetic damage...Full Text Available

2002-12-10

362

Activation of cycasin to a mutagen for Saccharomyces cerevisiae by rat intestinal flora.

A remarkable discovery of recent years is that, despite the complexity of ageing, simple genetic interventions can increase lifespan and improve health during ageing in laboratory animals. The pathways...Full Text Available

2011-05-01

363

A study of the genetics of dieldrin-resistance in the housefly (Musca domestica L.)*

Genetic test systems involving microorganisms and liver enzyme preparations may be insufficient to detect compounds that require breakdown by enzymes provided by the microbial flora of the intestinal...Full Text Available

1983-02-01

364

A multi-marker model for detecting chromosomal segments displaying QTL activity

Reciprocal mass crosses and back-crosses were performed between two homogeneous strains of the housefly (Musca domestica L.), representing the extremes in susceptibility and resistance...Full Text Available

1963-01-01

365

A homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, ? cell hyperplasia, and islet cell tumor

A statistical method is presented for detecting quantitative trait loci (QTLs), based on the linear model. Unlike methods able to detect a few well separated QTLs and to estimate their effects and positions, this method considers the genome as a whole and enables the detection of chromosomal segments involved in the differences between two homozygous lines, and their backcross, doubled haploid, or F[sub 2] progenies, for a quantitative trait. Genetic markers must be codominant, but missing markers are accepted, provided they are missing independently from the experiment. Asymptotic properties, which are of practical use, are developed. This method does not rely on strong genetic hypotheses, and thus does not permit any precise genetic analysis of the trait under study, but it does assess which regions of the genome are involved, whatever the complexity of the genetic determinism (number, effects and ...

1993-08-01

366

A haplotype map of the human genome

ObjectiveThe goal of the study was to investigate the genetic and molecular basis of a novel syndrome of marked hyperglucagonemia and pancreatic α cell hyperplasia...Full Text Available

2009-11-01

367

A combination of transposable elements and magnetic cell sorting provides a very efficient transgenesis system for chicken primary erythroid progenitors

Inherited genetic variation has a critical but as yet largely uncharacterized role in human disease. Here we report a public database of common variation in the human genome: more than one million...Full Text Available

2005-10-27

368

A Turquoise Mutant Genetically Separates Expression of Genes Encoding Phycoerythrin and Its Associated Linker Peptides

BackgroundStable transgenesis is an undeniable key to understanding any genetic system. Retrovirus-based insertional strategies, which feature several technical challenges when they...Full Text Available

369

A Suppression Subtractive Hybridization Approach Reveals Niche-Specific Genes That May Be Involved in Predator Avoidance in Marine Synechococcus Isolates

During complementary chromatic adaptation (CCA), cyanobacterial light harvesting structures called phycobilisomes are restructured in response to ambient light quality shifts. Transcription of genes...Full Text Available

2002-02-01

370

A Practical Approach to Genetic Inducible Fate Mapping: A Visual Guide to Mark and Track Cells In Vivo

Picocyanobacteria of the genus Synechococcus are important contributors to marine primary production and are ubiquitous in the world's oceans. This genus is genetically diverse, and...Full Text Available

2006-04-01

371

A DNA transposon-based approach to validate oncogenic mutations in the mouse

Fate maps are generated by marking and tracking cells in vivo to determine how progenitors contribute to specific structures and cell types in developing and adult tissue. An advance in this...Full Text Available

372

29 CFR 2590.702-1 - Additional requirements prohibiting discrimination based on genetic information.

Large-scale cancer genome projects will soon be able to sequence many cancer genomes to comprehensively identify genetic changes in human cancer. Genome-wide association studies have also identified...Full Text Available

2008-12-16

373

The relationship between reclamation and sustainable economic development

...treated for leukemia. B' s physician, who is employed by the HMO, is considering a treatment plan that includes six-mercaptopurine, a drug for treating leukemia in most children. However, the drug could be fatal if taken by a small percentage of...

2010-07-01

374

Project scheduling with resources constraints: application in the equipment production for the oil industry; Scheduling de projetos com restricao de recursos: aplicacao na producao de equipamentos para a industria de petroleo

The purpose is to define sustainable economic development in the context of nonrenewable resources and to examine the changing nature of reclamation over time. Sustainable development is development that ensures the present utilization of resources and the environment does not damage prospects for their use by future generations. Polls show that the public is demanding higher environmental standards. One mechanism for achieving sustainable economic development for the nonrenewable resource sector is through reclamation. The Alberta government`s approach to reclamation is reviewed to show how reclamation and sustainable government are linked together. The history of reclamation legislation in Alberta is summarized. 10 refs.

1991-06-01

375

On the optimal taxation of common-pool resources

One of the essential steps in the main scope Project Management is the Time Management made by the planning and control of the project schedule. In this work is presented the resource constrained scheduling problem beyond its mathematical formulation and a review of papers about this issue. In sequence is presented a practical example of this model considering a simplified model of an engineering project schedule of oil production equipment. The results obtained with the model application are shown and the conclusions about the work with resource constrained scheduling problems. (author)

2008-07-01

376

British Library Electronic Table of Contents (United Kingdom)

Recent research developments in common-pool resource models emphasize the importance of links with ecological systems and the presence of non-linearities, thresholds and multiple steady states. In a recent paper Kossioris et al. (2008) develop a methodology for deriving feedback Nash equilibria for non-linear differential games and apply this methodology to a common-pool resource model of a lake where pollution corresponds to benefits and at the same time affects the ecosystem services. This paper studies the structure of optimal state-dependent taxes that steer the combined economic-ecological system towards the trajectory of optimal management, and provides an algorithm for calculating such taxes.

2011-01-01

377

It is petrochemical of the waste plastic; Hai purasutikku no yuka

Hydrocarbon and mineral resources of the Uinta Basin, Utah and Colorado

It becomes a cause of the air pollution by the generation of hydrogen chloride, when it is incinerated, when it decays, even if the plastic which becomes spent is buried. Every year, it is abundantly discharged and accumulates. Countries and enterprises, etc. carry out the examination for non-polluting processing and resource recycling of the waste plastic for material recycling and development by methods such as thermal recycling, practical application. In this paper, the following are examined: Plastic output and transition of the situation of the disposal quantity, resource recycling and problem. It wants to explain the challenge of more and more efficient resource recycling. (NEDO)

1999-11-01

378

BUBL LINK: Computer programming - visual basic

The Uinta Basin is an important hydrocarbon producing area, with extensive resources of hydrocarbon, bitumen, and fossil fuels. Gilsonite, tar sands, oil shale and coal are found in abundance with the cretaceous and Tertiary sedimentary rocks. The 25 papers include discussion on: leasing; thermal maturity of rocks and hydrocarbon deposits; influence of source rock type, thermal maturity and migration on composition and distribution of the natural gas; drilling; geology; structural evolution of gilsonite dykes; reclamation of coal mines; oil shale resources; and uranium mining.

1992-01-01

379

Application of Resource Portfolio Concept in Nuclear Regulatory Infrastructure Support

...BUBL LINK: Computer programming - visual basic BUBL LINK Catalogue of Internet Resources Home | Search | Subject Menus | Countries ...O | P | Q | R | S | T | U | V | W | X | Y | Z Computer programming - visual basic Titles ... Author: Microsoft Subjects: computer programming - visual basic DeweyClass: 005.133 Resource type: software SearchVB....com Subjects: computer programming - visual basic DeweyClass: 005.133 Resource type: index VB Helper Tutorials ...

380

Alberta`s coal resources and the future

As the new entrants in the global nuclear construction market are increasing and the establishment of an effective and sustainable regulatory infrastructure becomes more important, they have requested international assistance from the international nuclear communities with mature nuclear regulatory programmes. It needs to optimize the use of limited resources from regulatory organization providing support to regulatory infrastructure of new comers. This paper suggests the resource portfolio concept like a GE/Mckinsey Matrix used in business management and tries to apply it to the current needs considered in the regulatory support program in Korea as the case study

2010-10-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

381

AONE Launches New Executive Coaching Resource for Members

The Kootenay, Luscar/Manville, and Belly River Groups, and the Horseshoe Canyon and Scollard Coalspur Formations are the most important coal measures in Alberta. Estimated current resources and reserves are 89 and 35 billion tonnes, respectively. Ultimate resources and reserves are 2100 and 660 billion tonnes, respectively. Most of the reserves are subbituminous and require underground mining methods. Current production is approximately 39 million tonnes per year, primarily subbituminous coal that is used for domestic electrical generation. Bituminous coal is exported. Long-term development will depend on markets, price, and infrastructure. 11 refs., 4 figs.

1996-12-31

382

British Library Electronic Table of Contents (United Kingdom)

The American Organization of Nurse Executives (AONE) and The Leadership Studio have collaborated to create a one-of-a-kind Executive Coaching Resource Center for nurse leaders and their teams. This resource-designed specifically for AONE members-is a one-stop web-based library developed to assist nurse leaders who want to learn more about utilizing executive coaching services. It focuses on the overall benefits of coaching for nurse leaders-both tangible and intangible-and provides return on investment information for executive coaching based on the most current research.

2009-01-01

383

Stochastic Optimization Approaches for Solving Sudoku

Optimal Parameter Selection of Power System Stabilizer using Genetic Algorithm

In this paper the Sudoku problem is solved using stochastic search techniques and these are: Cultural Genetic Algorithm (CGA), Repulsive Particle Swarm Optimization (RPSO), Quantum Simulated Annealing (QSA) and the Hybrid method that combines Genetic Algorithm with Simulated Annealing (HGASA). The results obtained show that the CGA, QSA and HGASA are able to solve the Sudoku puzzle with CGA finding a solution in 28 seconds, while QSA finding a solution in 65 seconds and HGASA in 1.447 seconds. This is mainly because HGASA combines the parallel searching of GA with the flexibility of SA. The RPSO was found to be unable to solve the puzzle.

2008-01-01

384

Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent

In this paper, it is suggested that the selection method of optimal parameter of power system stabilizer (PSS) with robustness in low frequency oscillation for power system using real variable elitism genetic algorithm (RVEGA). The optimal parameters were selected in the case of power system stabilizer with one lead compensator, and two lead compensator. Also, the frequency responses characteristics of PSS, the system eigenvalues criterion and the dynamic characteristics were considered in the normal load and the heavy load, which proved usefulness of RVEGA compare with Yu's compensator design theory. (author). 20 refs., 15 figs., 8 tabs.

1999-06-01

385

Estimated values of the genetic and somatic radiation exposure of the Bulgarian population in 1976

Gaussian-process models are developed to detect genetic linkage using complete high-resolution maps of identity by descent between affected relative pairs. Approximations are given for the significance level and power of the likelihood-ratio test of no linkage and for likelihood-ratio confidence regions for trait loci. The sample sizes required to detect linkage by using different classes of affected relative pairs are compared, and the problem of combining data from different classes of relatives is discussed. 23 refs., 2 figs.

1993-07-01

386

Characterization of eight microsatellite markers in the white sea bream, Diplodus sargus (Teleostei, Sparidae)

The genetically and leukemia-significant doses (GSD and LSD) were calculated from the average gonad and bone marrow doses caused by the most frequently applied radiopharmaceuticals in Bulgaria in 1976. Because of the lack of information about the age groups of the patients examined assumptions have been made which led to estimated values of 0.97 mrad for GSD and 2.0 mrad for LSD which must be considered as the upper limit of the real GSD and LSD. The influence of the different radiopharmaceuticals on the average radiation exposure of the population is discussed. (author).

1976-01-01

387

British Library Electronic Table of Contents (United Kingdom)

Abstract The white sea bream, Diplodus sargus (Teleostei, Sparidae), is a species with a high commercial importance in Mediterranean aquaculture. There is currently little information available about the genetic characteristics of cultured populations. In this survey, we have developed eight polymorphic microsatellites for the white sea bream using an enriched genome library protocol. All of them were polymorphic in the 67 individuals tested, 32 of which were wild specimens, and 35 were individuals from a captive F1 broodstock. These markers can potentially be useful tools for use in population genetic studies.

2008-01-01

388

An improved colony PCR procedure for genetic screening of Chlorella and related microalgae.

Algorithm for assessment of mean annual gonad dose and genetically significant dose from the data of personal dosimetry

A colony PCR technique was applied for both genomic and chloroplast DNA in the green microalgae Chlorella. Of five different lysis buffers, Chelex-100 was superior for DNA extraction, PCR and DNA storage. It also was insensitive to variations in cell density. The conditions established for an improved PCR formulation are applicable for screening of genetically-engineered transformants as well as bioprospecting of natural microalgal isolates. Besides multiple Chlorella species, we also demonstrate the efficacy of Chelex-100 for colony PCR with a number of other microalgal strains, including Chlamydomonas reinhardtii, Dunaliella salina, Nannochloropsis sp., Coccomyxa sp., and Thalassiosira pseudonana. PMID:21431847

2011-03-24

389

During one year more than 40,000 items of information on radiation exposure of personnel involved in the handling of radiation sources and more than 5,000,000 items on irradiation of other people are collected in the authors' laboratory. Considerable progress in assessment of mean annual gonad dose of genetically sifnificant dose was attained by means of an algorithm for a personal computer. This simple and inexpensive system has led to a higher accuracy in the application of protective measures. (author).

1985-10-22

390

Web Policies & Notices

Resources & Guides Schools Airmen Testing FAA Academy Federal Aviation Administration Web Policies & Notices Print Email | Updated: 4:46 pm ET March 2, 2011 Employment...

2011-10-08

391

Weather - Hanford Site

Water resources management in Asia. Volume 1. Main report. World Bank technical paper

to Cool Spots Hanford Fun Facts Classroom Projects Famous People of Hanford Counterintelligence Home Employee Responsibilities CI Information CI Resources Points of Contact...

2011-10-01

392

The Lithium future-resources, recycling, and the environment

The report, Water Resources Management in Asia, has three objectives: To describe the situation confronting the region's borrowers, devise approaches to better deal with the present and future water related problems that affect their well-being and equip the staff to actively participate in the regional and Bank-wide efforts to strengthen the sector. The principal water resources problems and issues have been placed in four categories: Institutional, long-term management and planning, real-time management and operations, and financial. Such an arrangement provides a perspective for examining concerns across all economic sectors and allows formulation of solutions that will constitute a truly comprehensive, balanced approach to the critical situation encountered in managing these resources. A summary of past Bank activities has confirmed that an historic approach is not adequate to address the pressing problems of ...

1993-01-01

393

British Library Electronic Table of Contents (United Kingdom)

Abstract:- The demand for Lithium-ion batteries as a major power source in portable electronic devices and vehicles is rapidly increasing. I use cumulative data of vehicle, mobile phone, laptop, and digital camera production to show that demand will overshoot the available global Lithium resources before 2025. Even if 100% of all Lithium-ion batteries were recycled today, recycling could not prevent this resource depletion in time. As the increasing Lithium scarcity will increase the price, it will be feasible to mine diluted resources with a strong environmental impact. I highlight these impacts in Lithium-rich Bolivia, the potential new -Saudi Arabia of Lithium.- Lithium extraction is likely to cause substantial water pollution, and-through impacts on native diversity-facilitate human he...

2011-01-01

394

The Global Biodiversity Information Facility (GBIF): Infrastructure, standards, access to data and tools to forecast climate change impacts on marine resources

The European Bioinformatics Institute's data resources

English 1 Feb 2009 [1 p.] United Kingdom Andelman, S Kins, Nick

2009-02-01

395

Splinter Protection for Airbase Firefighting Resources

As the amount of biological data grows, so does the need for biologists to store and access this information in central repositories in a free and unambiguous manner. The European Bioinformatics Institute...Full Text Available

2003-01-01

396

Space Weather Prediction Center Education and Outreach

... 36 7 Corrugated Steel Pipe Concept Layout--Elevation ..... 37 viii ... revetment. 3. Land Use ... Corner modules and capping blocks are available. ...

1989-12-01

397

Snow Survey & Water Supply | NRCS

Education resources dealing with solar-terrestrial physics, solar effects, solar radiation, etc. Includes links to short reference papers on subjects ... ...

398

SPASE Resource Description - the VHO - NASA

Programs & Services Technical Resources Land Use Soils Water Snow Survey & Water Supply Water Management Water Quality Watersheds Wetlands Air Plants & Animals Energy Climate...

2011-08-21

399

SAFETY--Water Resources Division National Pollutant Discharge...

The potentials of the spherical sensor and nearby conductors are controlled by ... Incoming data are continuously monitored by algorithms in the software to ... launched together with FM5 (Rumba) by a Soyuz-Fregat rocket from Baikonur. ...

400

Resources for Observing at CTIO

Provisions (a) NPDES field personnel shall be currently trained and certified in CPR and basic first-aid procedures. (b) NPDES field personnel shall be aware of the...

2011-09-24

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

401

Resource-loaded planning for ALICE

we have a colloquium scheduled. Computing: register your machine and check our network security and visitor computer policies. For Our Information: Once arranged, please let us...

2011-02-25

402

Research Activities in the Spokane, Washington, Field Office...

The ALICE experimental area management team faces various challenges when it comes to sharing scarce resources, indispensable to any efficient installation in a category one worksite. Space, cranes, jigs, and personnel with key competences have to be carefully allocated to activities so as to avoid slowing down work progress. To this intent, a resource loaded planning has been developed that allows highlighting coactivities and prioritizing critical tasks. It uses the built-in capabilities of Microsoft Project. The use of this scheduling tool leads to a more efficient use of time and a safer work environment. The installation sequence resulting from this schedule is presented in this paper. The first part of the sequence focuses on the revision of the coils in the SX2 building. The dipole has then to be installed in the RB26 side of the UX25 cavern. This complex and resource intensive activity has to be performed in ...

2005-01-01

403

Regional assessment of nonforestry related biomass resources: Virginia

other chemical applications include use in water softeners, detergents, and food additives. The development of phosphate resources as a leasable commodity provides income to...

2011-08-20

404

Regional assessment of nonforestry related biomass resources: Florida

This document is a collection of spreadsheets detailing on a county by county basis the agricultural crop, agricultural wastes, municipal wastes, and industrial wastes of Virginia that are potential biomass energy sources.

1988-11-01

405

Regional assessment of nonforestry related biomass resources: Alabama

This document is a collection of spreadsheets detailing in a county by county manner the agricultural crop, agricultural wastes, municipal wastes and industrial wastes in Florida that are potential biomass energy sources.

1988-11-01

406

Reformulation of Consumer Health Queries with Professional Terminology: A Pilot Study

This document is a collection of spreadsheets detailing on a county by county basis the agricultural crop, agricultural wastes, municipal wastes and industrial wastes of Alabama that are potential biomass energy sources.

1988-11-01

407

Recent aspects of new resources for chemical industry- petroleum, CO/H/sub 2/ and biomass materials

Background The Internet is becoming an increasingly important resource for health-information seekers. However, consumers often do not use effective search...Full Text Available

408

Navy Medical Resource Planning: Rates of Illness for Various ...

Some Japanese and US coal liquefaction research projects are listed.

1980-02-01

409

NWRC Weekly Highlights 8/14/2008

... sample. Hosoitalization Data Hospital admission rates across Navy ships :.n 1985 and 1975 are presented in Table 17. ...

2011-05-13

410

Live Web Chat: Earthquakes - How, Where and Why? - NASA Jet ...

vetted educational resources. (Gregory Smith, Lafayette, La., 337-266-8501) Award for DARPA Competition: Scott Wilson, spatial analysis branch chief at the USGS National Wetlands...

2011-08-27

411

Invasive Species: State Resources - Colorado

Mar 2, 2010 ... The NASA/JPL Education Office works with educators -- both classroom teachers and informal educators -- to provide tools, resources and ...

412

Increasing access to Latin American social medicine resources: a preliminary report*

of Concern; Parks; Management; Monitoring Exotic and Invasive Species Northern Arizona University. Canyons, Cultures, and Environmental Change. Species of Concern; Contacts;...

2011-10-01

413

Impact of a Statewide Internet-Based Tobacco Cessation Intervention

Purpose: This preliminary report describes the development and implementation of a project to improve access to literature in Latin American social medicine (LASM).Methods:...Full Text Available

2003-10-01

414

History of Bioterrorism: Botulism

Background An increasing number of people have access to the Internet, and more people are seeking tobacco cessation resources online every year. Despite the...Full Text Available

415

Medline Plus

... Pan Flu Preparedness YouTube is Your Friend Additional Resources ... Response Hurricane Readiness in High-Risk Areas: Survey Results Elements of ...

416

Hanford Speakers Bureau - Hanford Site

Environmental planning for geothermal energy resource exploration, development, and utilization

to Cool Spots Hanford Fun Facts Classroom Projects Famous People of Hanford Counterintelligence Home Employee Responsibilities CI Information CI Resources Points of Contact...

2011-10-02

417

Dynamic Phenotypic Clustering in Noisy Ecosystems

The commercialization of geothermal energy resources consists of a sequence of exploration, development, and utilization activities. Each of these activities are beset by both generic and project specific technical, environmental, and institutional constraints which must be adequately resolved before geothermal operations can be conducted. This report presents a summary of selected environmental activities conducted during the early planning stages of geothermal resource commercialization. Three representative activities are elaborated upon. These include preliminary environmental planning for geothermal energy development in the Medicine Lake Highlands of California; potential alternatives for non-electric use of the geothermal resource at East Mesa in Imperial County, California; and site specific studies of the impacts from using East Mesa geothermal fluids to irrigate selected crops and indigenous climax vegetation.

1982-01-01

418

Does Your Class Have Questions About Earthquakes? - NASA Jet ...

In natural ecosystems, hundreds of species typically share the same environment and are connected by a dense network of interactions such as predation or competition for resources. Much is known about...Full Text Available

2011-03-01

419

Different modes of resource variation provide a critical test of ideal free distribution models

Mar 15, 2011 ... The NASA/JPL Education Office works with educators -- both classroom teachers and informal educators -- to provide tools, resources and ...

420

British Library Electronic Table of Contents (United Kingdom)

Ideal free distribution (IFD) models are perhaps the group of mathematical models of behavior that have been the most widely and successfully applied by empiricists. These models can be applied to nearly any situation in which consumers compete?by any mechanism?for resources that are patchily distributed in their environment. Although IFD models have come to be broadly accepted, experiments that simultaneously test more than a single prediction are rare. Instead, investigators normally either test (1) for a relationship between the distribution of consumers and the distribution of resources or (2) whether average fitnesses are equal across resource patches. We conducted experiments with pea aphids (Acyrthosiphon pisum Harris) feeding on two patches of fava beans (Vicia faba L.) to fully in...

2007-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

421

Department of the

Denali National Park and Preserve Geologic Resources Inventory Report

Waste Technology and Innovation Study Final Report ...Waste Technology and Innovation Study Final Report 21/18569/150554 ...Survey of waste and resource recovery related technology and innovation, including products and product uses

422

Data - SPASE Resource Description

... the Mississippian Antler orogeny (Condie and Sloan 1998). Mesozoic Era (251 to 65.5 million years ago) The ... half of the Paleozoic and beginning of the Mesozo...

423

Continuing the Work to Advance Normal Birth

Feb 23, 2011 ... The potentials of the spherical sensor and nearby conductors are ... Incoming data are continuously monitored by algorithms in the software to ..... together with FM6 (Salsa) by a Soyuz-Fregat rocket from Baikonur. ...

424

Choosing and Using a Plant DNA Barcode

The editor of The Journal of Perinatal Education describes the contents of this issue, which offer a broad range of resources, research, and inspiration for childbirth educators.

2005-01-01

425

Chinese Geothermal Data from WDC-Geophysics, Beijing

The main aim of DNA barcoding is to establish a shared community resource of DNA sequences that can be used for organismal identification and taxonomic clarification. This approach was successfully...Full Text Available

426

Center for Intelligent Information Retrieval

Abstract: Geothermal data available from WDC includes : a) Map of hot spring distribution in ... d) Data on geothermal resources in Zhejiang and Fujian. ...

427

An Energy-Efficient Resource Allocation Scheme for Mobile Ad Hoc Computational Grids

evaluation, novelty detection, resource discovery, interfaces and visualization, digital libraries, computational social science, and cross-lingual information retrieval. The CIIR...

2011-08-31

428

British Library Electronic Table of Contents (United Kingdom)

Due to recent advancements in mobile computing and communication technologies, mobile ad hoc computational Grids are emerging as a new computing paradigm, enabling innovative applications through sharing of computing resources among mobile devices without any pre-existing network infrastructure. Energy-efficient resource allocation is one of the key issues in mobile ad hoc computational Grids due to limited battery life of mobile nodes. To reduce energy consumption, we propose a hybrid power-based resource allocation scheme for allocation of interdependent tasks to nodes within mobile ad hoc computational Grid. The basic idea is to exploit dependencies and task type, and allocate interdependent tasks to nodes accessible at minimum transmission power. We also propose a power-based algorithm...

2011-01-01

429

A Cultural Resources Survey Testing, and Geomorphic ...

Genetic and physical location of the gene for Stargardt`s disease and further evidence for genetic homogeneity

... Aerial photographs were provided by Mr. Grover P. ... Dr. Beverely J. Watkins conducted the records search and wrote the historic research. x,/ ...

1987-04-01

430

The environmentally sound management of low-grade fuels

Stargardt`s disease is inherited as an autosomal recessive condition characterized by a juvenile macular dystrophy. Genetic linkage analysis recently assigned the disease locus to chromosome 1p21-p13 with the best estimate for location of the gene near the locus D1S435. We performed linkage analysis in 34 North American families and 2 inbred families from the Kingdom of Saudi Arabia with 12 highly polymorphic markers on chromosome 1p flanking D1S435 between D1S207 and D1S223 and report significant linkage for all 12 markers with no evidence for genetic heterogeneity. Two-point linkage analysis demonstrated the Stargardt`s disease locus and D1S435 are linked with a maximum lod score of 17.17 at a recombination fraction of 1%. The markers UT851, D1S188, D1S424, UT2069, and D1S236 also demonstrated recombination fractions of 1% or less with two-point lod scores of 15.86, 21.93, 16.41, 20.36, and 17.37, respectively. To characterize this region ...

1994-09-01

431

Remote sensing for environmental monitoring and resource management. Volume 2

Selected papers from the conference are presented under seven sections covering: an overview of the environmental and health implications of low-grade fuel use; fuel resources and recovery; exploitation of peat and wood as a fuel; oil shale resources, processing and use; technological approaches to the reduction of environmental impacts associated with oil shale processing and use; technological approaches to reducing the environmental impacts of low-grade coal use; and environmentally sound technical options for low-grade fuel use.

1992-01-01

432

Peter Mbile | World Resources Institute

The subject of this volume is remote sensing for environmental monitoring and resource management. This session is divided in eight parts. First part is on general topics, methodology and meteorology. Second part is on geology, environment and land cover. Third part is on disaster monitoring. Fourth part is on operational status of remote sensing. Fifth part is on coastal zones and inland waters. Sixth and seventh parts are on forestry and agriculture. Eighth part is on instrumentation and systems. (A.B.). refs., figs., tabs.

1992-12-31

433

Oil shale resources and exploration in Queensland, 1986-87

...as agro forestry subject matter specialist, eastern supervisor, conservation and GIS officer with the Ministry of Agriculture and WWF-Korup national park project, respectively, in south west Cameroon . Peter holds joint Honours BSc in Forestry & Soil Science (WALES-UK) and MSc Resource Management (Edinburgh-UK)....

434

Oil shale in China: resources and utilization

Exploration for oil shale in Queensland between June 1986 and July 1987 continued over 12 deposits ranging in age from Permian to Tertiary. The total estimated resource of shale oil contained within these deposits is 4479 GL (28.2 billion barrels). 4 refs., 1 fig., 1 tab.

1988-10-01

435

China is continuing to extract oil from kerogen shale despite having a crude production capacity of 100 Mt a year. Among the reasons for this policy are the country's rich oil shale resources, comparatively mature extraction techniques, and a comprehensive utilization of the shale that has proved to be economically profitable. China has oil shale deposits of 340 Gt, equivalent to 24.5 Gt of shale oil, to rank fourth in the world after the U.S., Brazil, and the Soviet Union.

1984-05-01

436

NAME=\\

Mitigating socio-economic impacts of energy development

... Beltaos, J. T. Gardner, J. J. Gibson, R. J. Granger, R. Leconte, D. L. Peters, A. Pietroniro, L. A. Romolo and B. Toth Published: Feb 01, 2006 View all Articles from this Magazine »MOST POPULAR RELATED SEARCHES climate change, risk assessments, biodiversity, forestry, remote sensing, natural resource, fisheries, information systems, Environmental - Monitoring, environmental monitoring, exposure assessments, natural resource ...

437

Lignocellulosic feedstock resource assessment

This study provides information on energy resource development and the efforts of State and local communities in the Rocky Mountain, Appalachian, and coastal regions to deal with the related social and economic impacts. It also provides information on the range of options and resources generally available to States and local communities from local, State, industry, and Federal sources to plan for and mitigate the adverse effects of energy development. Onsite visits and interviews with State, local, and Federal officials and private industry involved in mitigating socioeconomic impacts were made.

1982-03-02

438

Geology and our future: summary of a workshop report

This report provides overall state and national information on the quantity, availability, and costs of current and potential feedstocks for ethanol production in the United States. It characterizes end uses and physical characteristics of feedstocks, and presents relevant information that affects the economic and technical feasibility of ethanol production from these feedstocks. The data can help researchers focus ethanol conversion research efforts on feedstocks that are compatible with the resource base.

1998-09-01

439

Feasibility study for a 10 MM GPY fuel ethanol plant, Brady Hot Springs, Nevada. Volume II. Geothermal resource, agricultural feedstock, markets and economic viability

This report highlights the significance of the geological sciences to the nation and to society. Discussions include understanding plate tectonics and surface processes, exploring the continental crust, ocean basins and the deep earth, applications of geology to social problems such as mineral resources, waste disposal, siting of critical facilities, geological hazards, water resources management, and coastal zones. The state of health of geological research is also discussed. (ACR)

1983-01-01

440

Direct application of West Coast geothermal resources in a wet-corn-milling plant. Final report

The issues of the geothermal resource at Brady's Hot Springs are dealt with: the prospective supply of feedstocks to the ethanol plant, the markets for the spent grain by-products of the plant, the storage, handling and transshipment requirements for the feedstocks and by-products from a rail siding facility at Fernley, the probable market for fuel ethanol in the region, and an assessment of the economic viability of the entire undertaking.

1980-09-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

441

The engineering and economic feasibility of using the geothermal resources in East Mesa, California, in a new corn processing plant is evaluated. Institutional barriers were also identified and evaluated. Several alternative plant designs which used geothermal energy were developed. A capital cost estimate and rate of return type of economic analysis were performed to evaluate each alternative. (MHR)

1981-03-01

442

Coal bibliography

BUBL LINK: Oceanographic data

This report contains basic bibliographic data for reports held by Resource Management and Mining (Ministry of Energy) in its Coal Technical Information System (CTIS). This system contains a large number of published and unpublished reports relating to New Zealand's coal, peat, and oil shale resources. This material has been accumulated from a wide range of sources and is of widely varying quality.

1987-01-01

443

BUBL LINK: Natural language processing

...6 Resource type: reference data Global Change Master Directory An extensive source of information about satellite and in situ Earth science data, with broad coverage of the atmosphere, hydrosphere, oceans, solid earth, and biosphere. Author: NASA Subjects: climatology, global change, oceanographic data DeweyClass: 551.6 Resource type: documents, news International ...

444

Toward an environmental and natural resources management strategy for ANE countries in the 1990s

... Author: Radev, Dragomir R. Subjects: natural language processing DeweyClass: 764 Resource type: document Natural Language Processing Research Group Research Group based in the Department of Computer Science, University of Sheffield. Conducts research into natural language analysis topics including data mining/information extraction, dialogue, and semantics. Author: Department of Computer Science, University of Sheffield Subjects: natural language processing DeweyClass: 764 Resource ...

445

The Spratlys: Islands nowhere else? Energy resources as a conflict factor and co-operation factor in East Asia; Die Spratlys: Inseln im Nirgendwo? Energieressourcen als Konflikt- und Kooperationsfaktor in Ostasien

An initial draft of an environmental and natural resource strategy for the Asia Near/East region in the 1990's is presented. The report contains five chapters. Chapter I provides an analytic framework that links natural resources, their extent, quality, and management with economic growth in the region. Chapter II contains a more detailed description and analysis of key resource problems that are restricting economic growth and have a severe negative impact on standard of living and quality of life. The most serious of these are soil and water degradation; destruction of natural forests, wetlands, and coastal zones; inefficient energy use and industrial pollution; and lack of environmental services. Chapters III and IV describe 20 specific opportunities for working toward sustainable economic growth through protection and enhancement of the natural resource base. Opportunities for action were ...

1990-01-01

446

Economic evaluation of oil shale and tar sands resources located in the state of Utah. Phase I: final report

In the contribution under consideration, the author reports on the energy resources as a conflict factor and co-operation factor in East Asia on the basis of the Spratly islands. The main aspects of this contribution are: topography of the Spratly islands; history and actual claims; evaluation of the claims; strategic significance of the islands; resources of oil and natural gas as a conflict factor; resources of oil and natural gas as a co-operation factor. The resources of oil and natural gas have intensified the conflict around the Spratly islands in the last few decades. Due to the unsettled situation relating to international law six countries could claim the potentially energy-rich area having a geo-strategic instrument of power. Due to a treaty and due to the new common research studies of the neighbouring countries a phase of stability can be expected. The increasing involvement of China in the ...

2006-07-01

447

Devolution and human resources in primary healthcare in rural Mali

Managing public lands for maximum social benefit is becoming an increasingly complex task. The growing need for domestically produced mineral raw materials and energy, and the conflicting interests over the use of public lands, have added new dimensions to the management issues. This report covers the first phase of a long-term program initiated by the Division of State Lands to improve their capability to evaluate the tar-sand and oil-shale resources in Utah. The scope of this phase of the study was limited to examination and analysis of existing information and to development models for data processing and resource evaluation. The study was effective in identifying problem areas and demonstrating the potential value of the proposed systems for management of state lands. It is anticipated that effective evaluation of the oil-shale and tar-sand resources in Utah, supported by readily accessible physical data, will lead to ...

1981-03-01

448

Cameron synthetic fuels report

Devolution, as other types of decentralization (e.g. deconcentration, delegation, privatization), profoundly changes governance relations in the health system. Devolution is meant to affect performance of the health system by transferring responsibilities and authority to locally elected governments. The key question of this article is: what does devolution mean for human resources for health in Mali?This article assesses the key advantages and dilemmas associated with devolution such as responsiveness to local needs, downward accountability and health worker retention. Challenges of politics and capacities are also addressed in relation to human resources for health at the local level. Examples are derived from experiences in Mali with a capacity development programme and from case studies of other countries. It is not research findings that are presented, but highlights of key issues at stake aimed at inspiring the debate in Mali and ...

2011-06-08

449

Analyses of mixed hydrocarbon binary thermodynamic cycles for moderate temperature geothermal resources

The increasing scarcity of conventional crude oil resources, as well as the sharply higher prices of crude oil, will generate increased interest in heavy oil, tar sands, and oil shale as potential substitutes. For all of these unconventional oil resources, extraction will be much more difficult, time consuming, and costly than for conventional crude oil. Although the inplace resources are vast and exist in many areas including the United States, the USSR, western Europe, Canada, and Latin America, probably only a small fraction of the inplace resources will prove to be economically extractable. These unconventional oil resources are now being developed in several locations around the world, and depending upon the exact definition probably account for less than 1 percent of current world oil supplies. The major current developments include: Canadian tar sands. Heavy oil production at ...

1980-06-01

450

The somatically significant dose, SSD, and analog of the GSD, the genetically significant dose

A number of binary geothermal cycles utilizing mixed hydrocarbon working fluids were analyzed with the overall objective of finding a working fluid which can produce low-cost electrical energy using a moderately low temperature geothermal resource. Both boiling and supercritical shell-and-tube cycles were considered. The performance of a dual-boiling isobutane cycle supplied by a 280/sup 0/F hydrothermal resource (corresponding to the 5MW pilot plant at the Raft River site in Idaho) was selected as a reference. To investigate the effect of resource temperature on the choice of working fluid, several analyses were conducted for a 360/sup 0/F hydrothermal resource, which is representative of the Heber resource in California. The hydrocarbon working fluids analyzed included methane, ethane, propane, isobutane, isopentane, hexane, heptane, and mixtures of those pure hydrocarbons. For ...

1981-01-01

451

On the genetic and somatic radiation doses in radiotherapy of inflammatory and degenerative diseases of bones, joints and soft parts

The medical applications of radiation comprise three main fields namely: Diagnostic Radiology, Radiotherapy and Nuclear Medicine. With the new weighting factors of ICRP (IC91a) the effective dose due to medical applications can be established. I is common to separate the effective dose into the genetic part and the somatic part, SED. In dealing with gonad doses it is important to account for the age of the person at the time of exposure as this will influence the number of children still to be expected from that person. The resulting dose will then be called the genetically significant dose, GSD. In a similar fashion this age factor will be important in considering the chance of tumor induction. The age of patients differs considerably from the average age of the general population. This age difference has to be accounted for if a comparison is to be made with other sources of radiation. This justifies establishing a somatically significant ...

1991-11-01

452

Molecular epidemiology of childhood leukemia with emphasis on chemical exposures

Dose measurements were performed in several body regions of patients suffering from inflammatory degenerative diseases (humeral epicondylitis, humeroscapular periarthritis, gonarthrosis, axillary hidradenitis, rheumatoid arthritis, coxarthrosis, parotitis). The problem of the radiation induction of neoplasms is predominant concerning somatic as well as genetic risk, discussed by example of the most frequently occurring organ cancer. Compared to the rate of breast cancer in the highly developed industrial states (5,000 to 6,000 cancers/100,000 women) the 'radiation induction' calculated according to a mathematical model of ICRP 26 (1.25 cases of death for breast cancers/100,000 women following for example irradiation of epicondylitis) is behind several powers of ten and not demonstrable. The genetic radiation exposure is also low. Derived from the measurements it is wrong to give up reliable and approved indications of radiotherapy of ...

1983-01-01

453

Human cDNA mapping using fluorescence in situ hybridization. Progress report, April 1, 1992--December 31, 1992

Developing markets in the Pacific Basin depend heavily on the production and export of consumer goods. The generation of hazardous waste as a by-product of industrial production can be linked to adverse health outcomes, such as childhood leukemia, in ways that are presently unknown. In California, exposures resulting from hazardous waste disposal are of concern in the etiology of childhood cancer. Approximately 63% of the 57 hazardous waste sites that the U.S. Environmental Protection Agency (USEPA) included in the national priority list under the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) statute were in the six-county San Francisco Bay area. This area includes California`s Silicon Valley, where a disproportionate majority of these sites are located. Although only one study links hazardous waste disposal to childhood leukemia evidence is accumulating that in utero and maternal pesticide exposures as well as chemical exposures during childhood are ...

1996-12-31

454

High genetic diversity of HIV-1 was found in men who have sex with men in Shijiazhuang, China

Genetic mapping is approached using the techniques of high resolution fluorescence in situ hybridization (FISH). This technology and the results of its application are designed to rapidly generate whole genome as tool box of expressed sequence to speed the identification of human disease genes. The results of this study are intended to dovetail with and to link the results of existing technologies for creating backbone YAC and genetic maps. In the first eight months, this approach generated 60--80% of the expressed sequence map, the remainder expected to be derived through more long-term, labor-intensive, regional chromosomal gene searches or sequencing. The laboratory has made significant progress in the set-up phase, in mapping fetal and adult brain and other cDNAs, in testing a model system for directly linking genetic and physical maps using FISH with small fragments, in setting up a database, and in establishing the ...

1993-03-04

455

British Library Electronic Table of Contents (United Kingdom)

Men who have sex with men (MSM) have become one of the populations with severely HIV prevalence in China. However, very few genetic studies have been done on HIV-1 spreading in this population. In this study, the genetic characterization of HIV-1 strains prevalent in the MSM in Shijiazhuang, China, was analyzed basing on the HIV-1 full-length gag, pol, and partial env gene. 21 drug-naive HIV-1 sero-positive patients were enrolled into the study. Full length gag, pol, partial env genes and some near full length genomes were amplified with nest RT-PCR followed by sequencing. Multiple subtypes, including CRF01_AE (52.9%), subtype B (35.3%) and CRF07_BC (11.8%), were found in the population. Phylogenetic analysis showed close relationship between our strains with those from Beijing MSM but not...

2011-01-01

456

Effective per-capita dose as a yardstick for medical radiation exposure of the population - a supplement or an alternative to the genetically significant dose

Absence of linkage of apparently single gene mediated ADHD with the human syntenic region of the mouse mutant coloboma

The genetically significant dose (GSD) is an index variable which exclusively allows to describe the genetic risk in the progeny of a population due to the application of ionizing radiation and radioactive substances in one part of this population. It may result in wrong interpretation of population exposure at increasing incidence of examinations in a population involving ionizing radiation and radioactive drugs at simultaneously increasing application of alternative methods in children and adolescents owing to the fact that it indicates a downward trend although somatic exposure of this population has increased. Therefore, it is recommended to state both the GSD and the level of somatic radiation exposure of the population taken from the individual sources for the comparison and assessment of radiation exposure from various sources in future. Although the somatically significant dose constitutes the suitable variable complementary to GSD in ...

1984-06-01

457

Genetic Modification of Short Rotation Poplar Biomass Feedstock for Efficient Conversion to Ethanol

Attention deficit disorder (ADHD) is a complex biobehavioral phenotype which affects up to 8% of the general population and often impairs social, academic, and job performance. Its origins are heterogeneous, but a significant genetic component is suggested by family and twin studies. The murine strain, coloboma, displays a spontaneously hyperactive phenotype that is responsive to dextroamphetamine and has been proposed as a genetic model for ADHD. Coloboma is a semi-dominant mutation that is caused by a hemizygous deletion of the SNAP-25 and other genes on mouse chromosome 2q. To test the possibility that the human homolog of the mouse coloboma gene(s) could be responsible for ADHD, we have carried out linkage studies with polymorphic markers in the region syntenic to coloboma (20p11-p12). Five families in which the pattern of inheritance of ADHD appears to be autosomal dominant were studied. Segregation analysis of the traits studied suggested ...

1995-12-18

458

Titles V and X of the Water Resources Development Act of 1983. Hearings before the Subcommittee on Water Resources of the Committee on Environment and Public Works, United States Senate, Ninety-Eighth Congress, Second Session, January 24 and 25, 1984

The Bioenergy Feedstock Development Program, Environmental Sciences Division, Oak Ridge National Laboratory is developing poplars (Populus species and hybrids) as sources of renewable energy, i.e., ethanol. Notable increases in adaptability, volume productivity, and pest/stress resistance have been achieved via classical selection and breeding and intensified cultural practices. Significant advances have also been made in the efficiencies of harvesting and handling systems. Given these and anticipated accomplishments, program leaders are considering shifting some attention to genetically modifying feedstock physical and chemical properties, so as to improve the efficiency with which feedstocks can be converted to ethanol. This report provides an in-depth review and synthesis of opportunities for and feasibilities of genetically modifying feedstock qualities via classical selection and breeding, marker-aided selection and breeding, and ...

2000-08-30

459

The temporal and spatial patterns and potential evaluation of China?s energy resources development

Two days of hearings on Titles V and X of the Water Resources Development Act of 1983 brought comments from representatives of several states, farm and transport industries, environmental groups, and concerned taxpayers. Title V requires the collection of new funds from users beyond a ceiling set for annual spending on water projects, while Title X proposes a cost-sharing partnership for certain navigation projects. Witnesses were requested to confine their comments to constructive alternatives to the proposed legislation. Additional material on the deep river study and statements submitted for the record follow the testimony of 28 witnesses.

1984-01-01

460

British Library Electronic Table of Contents (United Kingdom)

The issue of China?s energy supply security is not only the key problem which affects China?s rapid and sustainable development in the 21st century, but also the one which international attention focuses on. Based on the notable characteristic of spatial imbalance between energy production and consumption in China, this paper takes the evolution of China?s primary energy resources development(excluding hydropower) from 1949 to 2007 as the study object, with the aim to sum up the evolutive characteristics and laws of China?s energy resources development in the past nearly 60 years. Then, based on comprehensive considerations of coal?s, oil?s and natural gas?s basic reserves, qualities, geological conditions, production status, and ecological service function of every province, this paper ad...

2010-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

461

The surprising role of risk in utility integrated resource planning

Plan for addressing issues relating to oil shale plant siting

Integrated resource planning is rapidly emerging as the preferred planning process for electric utilities. Under IRP, planners project the initial and annual operating costs of different resource options and compare them using the revenue-requirements method (RRM)- a project-evaluation technique that discounts future costs (i.e., revenue requirements) into present values. The discount rate used for these computations is usually the firm's weighted-average cost of capital (WACC)-the weighted-average cost of the firm's equity and debt. The project alternative with the lowest present-value revenue requirement (PVRR) (i.e., lowest costs) emerges as the economic choice.

1993-04-01

462

Oil shale resources of the United States

The Western Research Institute plan for addressing oil shale plant siting methodology calls for identifying the available resources such as oil shale, water, topography and transportation, and human resources. Restrictions on development are addressed: land ownership, land use, water rights, environment, socioeconomics, culture, health and safety, and other institutional restrictions. Descriptions of the technologies for development of oil shale resources are included. The impacts of oil shale development on the environment, socioeconomic structure, water availability, and other conditions are discussed. Finally, the Western Research Institute plan proposes to integrate these topics to develop a flow chart for oil shale plant siting. Western Research Institute has (1) identified relative topics for shale oil plant siting, (2) surveyed both published and unpublished information, and (3) identified data gaps and research ...

1987-09-01

463

Offshore and inshore wave energy assessment: Asturias (N Spain)

Oil shales of the US represent a tremendous store of potential oil. Most of the deposits are relatively unknown and warrant additional investigation. The summary presented cannot hope to cover all of the deposits. Information about them is usually available only locally. However, the 3 best known deposits - the Green River formation, the Devonian black shales, and the retort member of the Phosphoria formation - represent well over 2 trillion bbl (300 x 10/sup 12/ ton) of potential oil in place. This is an oil resource large enough to supplement quite adequately the US petroleum supply, to extend the time available for realigning our energy supply mixes, and to help reach a satisfactory solution to our current energy dilemma. The concentrated resource in the Green River formation is obviously the next most feasible source of oil. If it cannot be developed, all the other deposits will have to wait until it can be. 100 references.

1980-11-01

464

British Library Electronic Table of Contents (United Kingdom)

The offshore and inshore wave energy resource in Asturias (N Spain) is studied using wave buoy data and a hindcast dataset spanning 44 years (1958-2001). Offshore average wave power and annual wave energy values are found to exceed 30 kW/m and 250 MWh/m, respectively, at 7 of the 11 study sites. This substantial resource is characterised in terms of the sea states involved. Most of the energy is provided by IV quadrant waves with significant wave heights between 2 m and 5 m and energy periods between 11 s and 13 s. After analysing the offshore resource, numerical modelling is used to investigate the inshore wave patterns. A coastal wave model is validated with wave buoy data and applied to three case studies representative of storm, winter and summer conditions. Inshore wave energy concent...

2010-01-01

465

Naturally fractured tight gas reservoir detection optimization

Local Perception of Environmental Change in a Semi-Arid Area of Northeast Brazil: A New Approach for the Use of Participatory Methods at the Level of Family Units

The goal of the work this quarter has been to partition and high-grade the Greater Green River basin for exploration efforts in the Upper Cretaceous tight gas play and to initiate resource assessment of the basin. The work plan for the quarter of July 1-September 30, 1998 comprised three tasks: (1) Refining the exploration process for deep, naturally fractured gas reservoirs; (2) Partitioning of the basin based on structure and areas of overpressure; (3) Examination of the Kinney and Canyon Creek fields with respect to the Cretaceous tight gas play and initiation of the resource assessment of the Vermilion sub-basin partition (which contains these two fields); and (4) Initiation analysis of the Deep Green River Partition with respect to the Stratos well and assessment of the resource in the partition.

1998-11-30

466

British Library Electronic Table of Contents (United Kingdom)

The diversity of plant resources in the Brazilian semi-arid region is being compromised by practices related to agriculture, pastures, and forest harvesting, especially in areas containing Caatinga vegetation (xeric shrublands and thorn forests). The impact of these practices constitutes a series of complex factors involving local issues, creating a need for further scientific studies on the social-environmental dynamics of natural resource use. Through participatory methods, the present study analyzed people?s representations about local environmental change processes in the Brazilian semi-arid region, taking into consideration local production systems, natural resources, and their importance. Environmental historical graphs were developed with nine local families to analyze landscape cha...

2011-01-01

467

Human cDNA mapping using fluorescence in situ hybridization. Final progress report, April 1, 1994--July 31, 1997

Geothermal resources of the Green River Basin, Wyoming, including thermal data for the Wyoming portion of the Thrust Belt

The ultimate goal of this research is to generate and apply novel technologies to speed completion and integration of the human genome map and sequence with biomedical problems. To do this, techniques were developed and genome-wide resources generated. This includes a genome-wide Mapped and Integrated BAC/PAC Resource that has been used for gene finding, map completion and anchoring, breakpoint definition and sequencing. In the last period of the grant, the Human Mapped BAC/PAC Resource was also applied to determine regions of human variation and to develop a novel paradigm of primate evolution through to humans. Further, in order to more rapidly evaluate animal models of human disease, a BAC Map of the mouse was generated in collaboration with the MTI Genome Center, Dr. Bruce Birren.

1997-12-31

468

Geological characteristics and resource potentials of oil shale in Ordos Basin, Center China

The geothermal resources of the Green River basin were investigated. Oil-well bottom-hole temperatures, thermal logs of wells, and heat flow data have been interpreted within a framework of geologic and hydrologic constraints. Basic thermal data, which includes the background thermal gradient and the highest recorded temperature and corresponding depth is tabulated. It was concluded that large areas are underlain by water at temperatures greater than 120/sup 0/F. Although much of this water is too deep to be economically tapped solely for geothermal use, oil and gas wells presently provide access to this significant geothermal resource. Isolated areas with high temperature gradients exist. These areas - many revealed by hot springs - represent geothermal systems which might presently be developed economically. 34 refs., 11 figs., 8 tabs. (ACR)

1985-01-01

469

Coal development potential in Pakistan

It has been shown that not only there are abundant oil, gas, coal, coal-bed gas, groundwater and giant uranium deposits but also there are abundant oil shale resources in Ordos basin. It has been shown also that the thickness of oil shale is, usually, 4-36m, oil-bearing 1.5%-13.7%, caloric value 1.66-20.98MJ/kg. The resource amount of oil shale with burial depth less than 2000 m is over 2000x108t (334). Within it, confirmed reserve is about 1x108t (121). Not only huge economic benefit but also precious experience in developing oil shale may be obtained in Ordos basin.

2010-09-15

470

BLM issues final EIS for Tract C-a offsite lease

A total of 48 papers were presented, and covered the following topics: the current situation in Pakistan with respect to development and utilization of coal resources; the policies that have been responsible for the development and utilization of coal resources in Pakistan; coal development and utilization in other developing nations e.g. Indonesia, Greece, Philippines, China, Thailand and Haiti; and technological developments in coal exploration; extraction, handling, transport and utilization which could accelerate future development of Pakistan's coal resources. Specific subjects covered include the use of coal in the cement industry of Pakistan; the production of briquettes for domestic use, development and training of personnel for the coal industry; and sources of finance for coal development projects. Particular emphasis is given throughout the conference to the Lakhra coal mine/power plant project which ...

1986-01-01

471

1992 Conversion Resources Supply Document

In October, 1986, the US Bureau of Land Management, White River Resource Area, issued the Final Environmental Impact Statement concerning Rio Blanco Oil Shale Company's request to lease an offtract site for disposal of overburden and spent shale from Tract C-a. A major issue which pitted Rio Blanco Oil Shale Company against many other members of the oil shale community was the covering up of oil shale resources on 84 Mesa. The oil shale resource under 84 Mesa may contain as much oil in place as Tract C-a itself. Some of the significant points concerning this issue are discussed. A summary of environmental consequences is given. 5 figures.

1986-12-01

472

Use of a trap garden to find additional genetically distinct isolates of the rust fungus Phragmidium violaceum to enhance biological control of European blackberry in Australia

In recent years conservation of electric power has become an integral part of utility planning. The 1980 Pacific Northwest Electric Power Planning and Conservation Act (Northwest Power Act) requires that the region consider conservation potential in planning acquisitions of resources to meet load growth. The Bonneville Power Administration (BPA) developed its first estimates of conservation potential in 1982. Since that time BPA has updated its conservation supply analyses as a part of its Resource Program and other planning efforts. Major updates were published in 1985 and in January 1990. This 1992 document presents updated supply curves, which are estimates of the savings potential over time (cumulative savings) at different cost levels of energy conservation measures (ECMs). ECMs are devices, pieces of equipment, or actions that increase the efficiency of electricity use and reduce the amount of electricity used by end-use equipment.

1992-03-01

473

British Library Electronic Table of Contents (United Kingdom)

Biological control agents can be more effective if their populations are genetically diverse, particularly when the target invasive plant comprises a range of genotypes with different susceptibilities and occurs across various microclimates. We report on the use of an efficient approach to find, in the native range, diverse isolates of a rust fungus for biological control. An outdoor trap garden containing various clones of invasive European blackberry (Rubus fruticosus agg.) collected in Australia, each with a different DNA phenotype, was established in France. Within 4?weeks of establishment, the leaf-rust fungus Phragmidium violaceum was recovered from all clones in the garden. Molecular analyses of eight recovered and purified isolates of the fungus from the garden revealed that they w...

2011-01-01

474

Two-photon calcium imaging from head-fixed Drosophila during optomotor walking behavior

British Library Electronic Table of Contents (United Kingdom)

Drosophila melanogaster is a model organism rich in genetic tools to manipulate and identify neural circuits involved in specific behaviors. Here we present a technique for two-photon calcium imaging in the central brain of head-fixed Drosophila walking on an air-supported ball. The ball's motion is tracked at high resolution and can be treated as a proxy for the fly's own movements. We used the genetically encoded calcium sensor, GCaMP3.0, to record from important elements of the motion-processing pathway, the horizontal-system lobula plate tangential cells (LPTCs) in the fly optic lobe. We presented motion stimuli to the tethered fly and found that calcium transients in horizontal-system neurons correlated with robust optomotor behavior during walking. Our technique allows both behavior ...

2010-01-01

475

The epidemiology of Graves' disease: Evidence of a genetic and an environmental contribution

British Library Electronic Table of Contents (United Kingdom)

Previous family and twin studies have indicated that Graves' disease has a heritable component. Family studies have also shown that some autoimmune disease cluster in families and genetic studies have been able to show shared susceptibility genes. In the present nation-wide study we describe familial risk for Graves' disease among parents and offspring, singleton siblings, twins and spouses with regard to age of onset, gender and number and type of affected family members. Additionally familial association of Graves' disease with any of 33 other autoimmune and related conditions was analyzed. The Swedish Multigeneration Register on 0-75-year-old subjects was linked to the Hospital Discharge Register from years 1987-2007. Standardized incidence ratios (SIRs) were calculated for individuals ...

2010-01-01

476

The effective per caput dose equivalent as a measure of medical radiation exposure of the population - a complement or an alternative to the genetically significant dose

Subjective effects to cannabis are associated with use, abuse and dependence after adjusting for genetic and environmental influences

The GSD must be considered as a quantity by means of which the risk in a given population can be described exclusively in terms of genetic risk. In cases of a simultaneous increase in the rate of examinations, the GSD may lead to a misinterpretation of the population exposure, suggesting a decreasing trend, although there is an actual increase in the somatic radiation exposure. It is recommended to indicate not only the GSD but also the amount of somatic radiation exposure of the population for each specific source when comparing and evaluating radiation exposures from different sources. Although the somatically significant dose formally would be suited as a complement to the GSD, it is recommended to use the effective per caput dose equivalent. It must be pointed out that the application of the concept of effective dose equivalent is only appropriate for comparative evaluations of the population exposure to different sources of radiation. (orig./HP).

1984-01-01

477

British Library Electronic Table of Contents (United Kingdom)

Background Previous reports in adults have suggested that the effects experienced after cannabis use can be described in terms of positive and negative subtypes that are heritable and are associated with abuse and dependence. This study extends existing research by inclusion of adolescents and young adults in an offspring of twins design which makes it possible to take into account genetic and environmental risks for substance use disorder. Methods Data were collected from 725 twin members of the Vietnam Era Twin Registry, 839 of their 12-32 year old biological offspring and 427 mothers. Offspring who had ever used cannabis (n=464) were asked the degree to which they typically experienced 13 subjective effects shortly after using cannabis. Latent class analysis (LCA) was used to derive sub...

2009-01-01

478

Somatic radiation risk in different mammography techniques

Somatic and genetic radiation exposure of the patient in digital subtraction angiography (DSA)

By measuring organ doses with TLD at an Alderson-Rando-phantom it was tested to evaluate the somatic risk for mammographies. Similarly as the genetic risk can be expressed by the genetic significant dose, the somatic risk can be expressed by the somatic significant dose index. The measurement results of the mammography show a large deviation of almost one power of ten with dependence of the chosen technique. In conventional xeroradiography and recording technique with foilless film the somatic radiation risk is the highest. By using amplifying foils in combination with high-sensitive films it is relatively small. Unfortunately the magnitude of the somatic risk in the different mammography techniques is in the ratio reciprocal to the corresponding image quality. At the time being the most favourable technique is mammography with a soft rastering method, although the xeromammography with additional high aluminium-filtering is a further ...

1981-01-01

479

Sequences of versatile, broad-host-range vectors of the RK2 family.

The somatic and genetic radiation exposure of patients undergoing Digital Subtraction Angiography (DSA) and traditional Film Arteriography (FA) of cranial, cervical, thoracic and abdominal vascular territories are compared. The radiation doses absorbed within the critical organs - red bone marrow, lung, thyroid gland and female breast - and in the gonads were measured using an anthropomorphic Alderson phantom. A Somatic Dose Index was calculated in order to estimate the somatic radiation risk. The somatic radiation exposure depends upon the location of the critical organs with respect to the entrance site of the x-ray beam, and can be reduced by an appropriate choice of the angiographic projection. Under this condition, the radiation exposure of the patient during DSA can be lower than during FA. For renal DSA an a.p. projection, the use of an abdominal compression device and careful caudal shielding of the field are advocated. (orig.).

1986-01-01

480

Risk assessment for radiation protection purposes

Plasmid pRK404-a smaller derivative of RK2-is a tetracycline-resistant broad-host-range vector that carries a multiple cloning site and the lacZ(alpha) peptide that enables blue/white selection for cloned inserts in Escherichia coli. We present herein the complete and annotated sequence of pRK404 and three related vectors-pRK437, pRK442, and pRK442(H). These derivatives have proven to be valuable tools for genetic manipulation in Gram-negative bacteria. The knowledge of their complete sequences will facilitate efficient future engineering of them and will enhance their general applicability to the design of genetic systems for use in organisms for which new genomic sequence data are becoming available.

2003-07-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

481

Review on the immunology of European sea bass Dicentrarchus labrax

In defining criteria for good protection against ionizing radiation, it is important to assess quantitatively the likely risk of any radiation exposure. The 'somatic' risks to the individual result mainly from induction of cancer in the organs irradiated, and these risks can now be estimated on the basis of numerous detailed epidemiological surveys of exposed human populations. Estimates of the risk of hereditary effects, from genetic changes induced in germ cells, are based largely on the frequency with which such effects are induced in other species. In both cases the risk at very low dose can be inferred using knowledge of the way in which radiation damage is caused in tissues. Coherent systems of radiation protection are based on a restriction of doses to the whole body and to individual organs, such that the induction of cancer and genetic harm is infrequent, and the threshold dose for causing other, 'non-stochastic', effects is not ...

1980-01-01

482

British Library Electronic Table of Contents (United Kingdom)

European sea bass (Dicentrarchus labrax L.) is a marine species of great economic importance, particularly in Mediterranean aquaculture. However, numerous pathogenic viruses, bacteria, fungi and parasites affect the species, causing various infectious diseases and thereby leading to the most heavy losses in aquaculture production of sea bass. In this respect, knowledge on molecular and genetic mechanisms of resistance to pathogens and specific features of immune response against various infectious agents should greatly benefit the development of effective vaccines and proper vaccination strategies in marker-assisted selection of fish resistant to a range of infections. To date, genetic knowledge on sea bass immune regulatory genes responsible for resistance to pathogens is relatively poor ...

2007-01-01

483

Phylogeography of rabies virus isolated from dogs in Brazil between 1985 and 2006

British Library Electronic Table of Contents (United Kingdom)

To establish the phylogeographic relationships in rabies viruses in Brazil, we studied a dataset retrieved from GenBank consisting of 71 genetic sequences from the coding region of the N gene of rabies viruses isolated in dogs over a period of 22?years. The Bayesian Markov chain Monte Carlo method available in the BEAST package was used with the GTR+G+?4 evolutionary model in conjunction with the relaxed uncorrelated lognormal molecular clock model and an exponential growth tree prior. A discrete phylogeographic diffusion model was also analyzed using a standard continuous-time Markov chain viewed with Google Earth to provide a spatial projection of the diffusion of genetic lineages based on their phylogeographic relationships. The topology of the time and substitution phylogenetic trees a...

2011-01-01

484

Novel Techniques and Their Wide Applications to Health Foods, Medical and Agricultural Biotechnology in Relation to Policy Making on Genetically Modified Crops and Foods

Mucosal Inflammation in Spondylarthritides: Past, Present, and Future

Selected applications of novel techniques in Agricultural Biotechnology, Health Food formulations and Medical Biotechnology are being reviewed with the aim of unraveling future developments and policy changes that are likely to open new markets for Biotechnology and prevent the shrinking or closing of existing ones. Amongst the selected novel techniques with applications in both Agricultural and Medical Biotechnology are: immobilized bacterial cells and enzymes, microencapsulation and liposome production, genetic manipulation of microorganisms, development of novel vaccines from plants, epigenomics of mammalian cells and organisms, and biocomputational tools for molecular modeling related to disease and Bioinformatics. Both fundamental and applied aspects of the emerging new techniques are being discussed in relation to their anticipated, marked impact on future markets and present policy changes that are needed for success in either Agricultural or Medical ...

2004-01-01

485

British Library Electronic Table of Contents (United Kingdom)

Spondylarthritides (SpA) and inflammatory bowel disease (IBD) are idiopathic, chronic inflammatory disorders. Although they are very distinct and well-defined entities, there is clinical and genetic evidence supporting some degree of overlap between the pathogenesis of the two. Subclinical gut inflammation is present in up to two thirds of all SpA patients and can evolve into IBD. This subclinical gut inflammation has been shown to be strongly associated with joint inflammation, providing a clue for a common pathophysiologic background. Despite extensive research progress in the field over the past few years, many questions remain unanswered. In this paper, we focus on the clinical, genetic, and pathophysiologic overlap of SpA and IBD. Furthermore, we discuss some of the targets that may i...

2011-01-01

486

Mary Lyon and the hypothesis of random X chromosome inactivation

British Library Electronic Table of Contents (United Kingdom)

The 50th anniversary of Mary Lyon?s 1961 Nature paper, proposing random inactivation in early embryonic life of one of the two X chromosomes in the cells of mammalian females, provides an opportunity to remember and celebrate the work of those involved. While the hypothesis was initially put forward by Lyon based on findings in the mouse, it was founded on earlier studies, notably the work of Susumu Ohno; it was also suggested independently by Beutler and colleagues using experimental evidence from a human X-linked disorder, glucose-6-phosphate dehydrogenase deficiency, and has proved to be of as great importance for human and medical genetics as it has for general mammalian genetics. Alongside the hypothesis itself, previous cytological studies of mouse and human chromosomes, and the obse...

2011-01-01

487

Isolation and characterization of microsatellite markers in Acca sellowiana (Berg) Burret.

Introduction to the Special Issue: Human Linkage Studies for Behavioral Traits

Acca sellowiana has commercial potential because of the quality and the unique flavor of its fruit. Conservation of natural populations and management of breeding programmes would benefit from the availability of molecular markers that could be used to characterize levels and distribution of genetic variability. Thus, 13 microsatellite markers were developed from an enriched genomic library of A. sellowiana. They were characterized using 40 samples. The expected and observed heterozygosities ranged from 0.513 to 0.913 and from 0.200 to 0.889, respectively. These are the first microsatellite loci characterized from A. sellowiana that will contribute to improve researches on the genetic conservation, characterization and breeding. PMID:21586063

2008-07-08

488

British Library Electronic Table of Contents (United Kingdom)

In the post Genome era, the aim of behavior genetics has shifted from estimating the relative contributions of genes and environmental factors to (co-)variation in human complex traits, to localization of genes and identification of functional genetic variants. This special issue reflects this transition and presents fifteen papers that report on genome-wide linkage scans for complex traits in humans and on methodological tools and innovations. Six papers focus on cognition and report overlapping linkage peaks on chromosomes 6p and 14p. Papers on addictive behavior, i.e. smoking and alcohol dependence and its endophenotypes, find moderate LOD scores on chromosomes 6p, 5q, 4p and 7q, respectively. Three papers concentrate on emotionality, depression and loneliness and examine chromosomes 2q...

2006-01-01

489

Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): Localization to chromosome band 7p14 and integration into the cytogenetic, physical, and genetic map of chromosome 7

Health risks arising from ionizing radiation and chemical pollutants

The gene encoding the human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R1) was mapped to chromosome 7 by PCR analysis of genomic DNA from a human/rodent somatic cell hybrid mapping panel. This assignment was confirmed and the gene localized to chromosome band 7p14 by fluorescence in situ hybridization. A yeast artificial chromosome containing ADCYAP1R1 was identified in the CEPH {open_quotes}B{close_quotes} Mega-YAC library. This YAC includes two highly polymorphic dinucleotide repeat sequences that will facilitate genetic studies of the contribution of ADCYAP1R1 in disease states of the central nervous and neuroendocrine systems. 13 refs., 1 fig.

1994-10-01

490

Habitat segregation and genetic relationship of two heptageniid mayflies, Epeorus latifolium and Epeorus l-nigrus, in the Shinano-gawa River basin

In quantifying health risks arising from radiation exposure and synergistic effects promoted by radiation the dose-effect relationship must be used as a basis. Special problems arise in the extrapolation of experimental results or in the treatment of data in the region of low doses administered over long periods of time. For radiation protection purposes, especially manifestations of cancer and genetic effects are significant. The International Commission on Radiation Protection has published binding guiding values on the basis of which to assess the risk of cancer. The cancer risk and genetic risks are estimated for relevant dose ranges and compared with other factors of civilization. For the most important chemical pollutants emitted into the environment the possibilities of impacts arising from synergistic effects are discussed on the basis of the rules and regulations specified in German antipollution legislation. (orig.) 891 HP/orig. 892 ...

1979-10-03

491

British Library Electronic Table of Contents (United Kingdom)

The heptageniid mayflies Epeorus latifolium and Epeorus l-nigrus are often the dominant species in the upper and midstream areas of Japanese rivers; as such, they play a significant role in river ecosystems. However, although these two species have been identified using the morphological characteristics of the male in its adult stage, it is impossible to differentiate them in their nymphal stage. We conducted a study to elucidate their distribution pattern, i.e., the current distribution of these two species in the Shinano-gawa River basin, based on quantitative field sampling and genetic analysis of nymphs and also some male adults; for these, it was possible to differentiate between the two species reliably. The data collected from the 30 study sites of the 1-year-long study revealed tha...

2011-01-01

492

Gravitational Lens Modeling with Genetic Algorithms and Particle Swarm Optimizers

Genomic architecture of aggression: Rare copy number variants in intermittent explosive disorder

Strong gravitational lensing of an extended object is described by a mapping from source to image coordinates that is nonlinear and cannot generally be inverted analytically. Determining the structure of the source intensity distribution also requires a description of the blurring effect due to a point spread function. This initial study uses an iterative gravitational lens modeling scheme based on the semilinear method to determine the linear parameters (source intensity profile) of a strongly lensed system. Our 'matrix-free' approach avoids construction of the lens and blurring operators while retaining the least squares formulation of the problem. The parameters of an analytical lens model are found through nonlinear optimization by an advanced genetic algorithm (GA) and particle swarm optimizer (PSO). These global optimization routines are designed to explore the parameter space thoroughly, mapping model degeneracies in detail. We develop a novel method that ...

2011-01-01

493

British Library Electronic Table of Contents (United Kingdom)

Abstract Copy number variants (CNVs) are known to be associated with complex neuropsychiatric disorders (e.g., schizophrenia and autism) but have not been explored in the isolated features of aggressive behaviors such as intermittent explosive disorder (IED). IED is characterized by recurrent episodes of aggression in which individuals act impulsively and grossly out of proportion from the involved stressors. Previous studies have identified genetic variants in the serotonergic pathway that play a role in susceptibility to this behavior, but additional contributors have not been identified. Therefore, to further delineate possible genetic influences, we investigated CNVs in individuals diagnosed with IED and/or personality disorder (PD). We carried out array comparative genomic hybridizati...

2011-01-01

494

Genetic testing for hereditary cancer: Effects of alexithymia and coping strategies on variations in anxiety before and after result disclosure

British Library Electronic Table of Contents (United Kingdom)

This study assessed the impact of the results of genetic testing for hereditary cancer from a multifactorial health psychology perspective, considering that emotional expression plays a key role in psychological adjustment. Measures of dispositional and transactional coping strategies, anxiety and alexithymia were filled out by 77 participants in a longitudinal study design. Statistical analyses were performed using general linear models and partial least squares path modelling, low-constraint methods that are particularly useful in the behavioural sciences. While anxiety levels prior to the result announcement were predictive of the distress experienced by noncarriers, considerable variability was observed for mutation carriers. Some subjects who had lower anxiety levels before the test d...

2011-01-01

495

Fault diagnosis on bottle filling plant using genetic-based neural network

British Library Electronic Table of Contents (United Kingdom)

Timely detection of the pneumatic system problems is important in industry. Many techniques have been employed to solve this problem. In this paper, Genetic Algorithm (GA) based optimal configuration of neural networks is proposed for fault diagnostic of bottle filling systems. Back-propagation is used for neural networks algorithm. The back-propagation algorithm had six inputs and one output. A fitness function was designed to the minimize execution time of ANN model by keeping the number of hidden layer(s) and nodes as low as possible while the mean square error of estimated output error is minimized. The designed GA-ANN combination and the graphical user interface (GUI) eliminate the trial and error process for selection of the fastest and most accurate configuration. The performance of...

2011-01-01

496

Design of recurrent neural network power system stabilizer based on genetic algorithm

Continuous human cell lines and method of making same

A new recurrent neural network power system stabilizer (RNNPSS) based on genetic algorithm (GA) was presented. It shows faster convergence than the linear quadratic regulator (LQR) stabilizer in a multi-machine power system, because the proposed GA based neural network was first trained off-line to determine the optimal values of the learning rates. Otherwise, the RNNPSS consists of just two layers. As such, the time consumption of the damping oscillations is lower than with conventional methods. In addition, the operating range of the RNNPSS is greater than that of the LQR and conventional three layer neural networks, since the RNNPSS can greatly reduce system complexity and effectively damp system oscillations. 9 refs., 7 figs.

2008-07-01

497

Channelrhodopsin-2 gene transduced into retinal ganglion cells restores functional vision in genetically blind rats

Substantially genetically stable continuous human cell lines derived from normal human mammary epithelial cells (HMEC) and processes for making and using the same. In a preferred embodiment, the cell lines are derived by treating normal human mammary epithelial tissue with a chemical carcinogen such as benzo(a)pyrene. The novel cell lines serve as useful substrates for elucidating the potential effects of a number of toxins, carcinogens and mutagens as well as of the addition of exogenous genetic material. The autogenic parent cells from which the cell lines are derived serve as convenient control samples for testing. The cell lines are not neoplastically transformed, although they have acquired several properties which distinguish them from their normal progenitors. 2 tabs.

1985-07-01

498

British Library Electronic Table of Contents (United Kingdom)

To test the hypothesis that transduction of the channelrhodopsin-2 (ChR2) gene, a microbial-type rhodopsin gene, into retinal ganglion cells of genetically blind rats will restore functional vision, we recorded visually evoked potentials and tested the experimental rats for the presence of optomotor responses. The N-terminal fragment of the ChR2 gene was fused to the fluorescent protein Venus and inserted into an adeno-associated virus to make AAV2-ChR2V. AAV2-ChR2V was injected intravitreally into the eyes of 6-month-old dystrophic RCS (rdy/rdy) rats. Visual function was evaluated six weeks after the injection by recording visually evoked potentials (VEPs) and testing optomotor responses. The expression of ChR2V in the retina was investigated histologically. We found that VEPs could not b...

2010-01-01

499

Australian experience with herbicide tolerant (HT) and Bacillus thuringiensis (Bt) cotton

British Library Electronic Table of Contents (United Kingdom)

Australia?s nationally consistent framework for gene technology regulation is underpinned by the Gene Technology Act 2000, administered by an independent decision-maker, the Gene Technology Regulator. The object of the Act is ?to protect the health and safety of people, and to protect the environment, by identifying risks posed by or as a result of gene technology, and by managing those risks through regulating certain dealings with genetically modified organisms?. Marketing and trade impacts are outside the scope of assessments required by the Act. Since 2001, seven licences have been issued for the commercial cultivation of genetically modified (GM) cotton with insect resistance and/or herbicide tolerance. Licences have also been issued for 32 GM cotton field trials with a broader range ...

2011-01-01

500

TLD assessment of mouse dosimetry during microCT imaging