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Fat graft myringoplasty with the newly developed surgical technique for chronic tympanic membrane perforation.  

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The purpose of this prospective clinical trial was to evaluate the success rate of our newly developed surgical technique for fat graft myringoplasty (FGM). We also aimed to assess the correlations between the size of perforations and closure rates, as well as the results of re-gained hearing in successful cases with respect to sizes of perforations. Thirty consecutive patients with persistent tympanic membrane perforation were included in this study. All patients underwent fat graft myringoplasty with a newly developed technique. Treatment success was defined as an intact tympanic membrane (TM) at the 3-month follow-up visit. Bone conduction (BC) and air conduction (AC) thresholds at the frequencies of 0.5, 1, 2, 3, and 4 kHz were recorded preoperatively and at the 3rd month postoperatively. The range of perforation sizes among the 30 patients was 7 mm in 13 of the patients (43 %), 6 mm in 8 of the patients (27 %), and 5 mm in nine of the patients (30 %). Closure of tympanic membrane perforations with this new technique was achieved in 27 out of the 30 patients, with a success rate of 90 %. The average of the air-bone gap (dB) was similar in preoperative and postoperative periods for 5- and 6-mm sized perforation groups (p = 0.09 and p = 0.49). However, in the 7-mm sized perforation group, the average of the air-bone gap (dB) was higher in the preoperative period than the postoperative period (p = 0.004). The average of the air-bone gap (dB) for all patients was higher in the preoperative period than the postoperative period (p = 0.001). In conclusion, FGM performed with this technique may be used as an alternative for the closure of tympanic membrane perforations larger than 5 mm. PMID:22983221

Koc, Sema; Akyuz, Servet; Gurbuzler, Levent; Aksakal, Ceyhun

2013-05-01

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A comparative study of different graft materials used in myringoplasty  

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Two hundred twenty cases of unilateral chronic suppurative otitis media (CSOM) with dry central perforation were chosen for this study and myringoplasty were done. Age group ranged from 13 to 48 years. Four types of autogenous tissues were used as graft material. Grafting was done by underlay technique when temporalis fascia, tragal perichondrium, areolar tissue were used as graft material and when fat graft was used the ear lobule fat was placed directly into perforation through transcanal r...

Singh, B. J.; Sengupta, A; Das, Sudip Kumar; Ghosh, D.; Basak, B.

2009-01-01

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ENDOSCOPE ASSISTED MYRINGOPLASTY  

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Full Text Available Myringoplasty is commonly done under microscopy. This article discusses the experience of the authors in performing myringoplasty using endoscope. Endoscope is being widely used to perform various surgeries. Endoscopes are very useful while operating in cavities. In this study authors report their results of 50 myringoplasties performed using endoscope. This article reveals that results of myringoplasty performed using endoscope are more or less similar to that of myringoplasty performed using microscope 5.

Balasubramanian Thiagarajan

2012-03-01

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Bilateral single sitting myringoplasty using tragal cartilage from one ear.  

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Though single sitting myringoplasty using temporalis fascia under general anesthesia has been documented in many studies, but ours is the first center to have started using tragal cartilage harvested from one ear to do bilateral myringoplasty in one sitting using local anesthesia with excellent results including very good graft uptake rate and audiological improvement without significant complications. PMID:24427733

Sood, Arvinder Singh

2013-12-01

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Transtympanic myringoplasty in children.  

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Our experience with myringoplasty by the transtympanic "push through' technique in paediatric patients is described. We have used this method in 40 children utilizing autologous temporalis fascia as the graft material. The procedures were all performed as day cases under general anaesthesia. The overall success rate for perforation closure was 77.5% at 6 months which is comparable to conventional methods. We conclude that the "push-through' technique is a safe, simple, reliable and cost-effective procedure that can be performed as a day case in paediatric patients. It avoids the necessity for pressure bandaging or formal ear packing. To our knowledge this is the first paper evaluating this technique in children. PMID:9152747

Srinivasan, V; Toynton, S C; Mangat, K S

1997-04-11

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Pneumatization correlated to myringoplasty and tubal function  

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The prognostic significance of the size of mastoid air cell system in the results of myringoplasty has been a matter of debate. Fifty ears with dry central perforation following C.S.O.M. were investigated. The size of mastoid air cell system was determined with planimetry of the X-ray picture and eustachian tube function was assessed using flourescein dye and nasal endoscopy. Myringoplasty was performed in all the 50 ears and postoperative results in terms of graft take up and hearing gain we...

Sethi, A.; Singh, I.; Agarwal, A. K.; Sareen, D.

2005-01-01

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Success of myringoplasty: our experience.  

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The purpose of this study is to compare the efficacy of myringoplasty with or without cortical mastoidectomy in terms of freedom from discharge, graft take up and improvement in hearing. This is a Clinical prospective study of 120 patients from among a group of patients with chronic suppurative otitis media. A detailed history and examination was conducted including pure tone audiogram. Patients were randomly divided into two groups; group A would undergo myringoplasty only and group B would undergo cortical mastoidectomy with myringoplasty. Patients were reviewed after 3 weeks for inspection of the operated ear. Second post-operative review was at 3 months for clinicoaudiological assessment. Group B was found to have slightly more improvement as compared to the other group. No significant difference in the success rates of graft take-up in patients with unilateral or bilateral disease was found. Higher take up rates were seen in large (91.83 %) and medium perforations (90.69 %). In all our failed cases, post-operative ear discharge continued to be a persistent and troubling problem. The average audiological gain was 12.88 dB in group B, whereas it was 12.40 dB in group A. The reduction of air bone gap within each group was found to be significant. There is no statistical significant data indicating that tympanoplasty with mastoidectomy yields better results. When considering the addition of a mastoidectomy to a Tympanoplasty, the performing surgeon should consider not only the potential added benefit but also potential risks and costs to the patient. PMID:24427599

Kamath, M Panduranga; Sreedharan, Suja; Rao, A Raghavendra; Raj, Vinay; Raju, Krishnam

2013-12-01

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Autologous Fat Grafting for Whole Breast Reconstruction  

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Summary: This is the first reported case of a patient who had a single-stage large-volume breast reconstruction with autologous fat grafting, following rotation flap approach (RoFA) mastectomy. The purpose of this case study was to evaluate the viability of reconstruction of the breast by autologous fat grafting alone, in the context of RoFA mastectomy. The hypothesis was that there would be minimal interval loss of autologous fat on the whole breast reconstruction side. Right RoFA mastectomy was used for resection of an invasive primary breast cancer and resulted in the right breast skin envelope. Eleven months later, the patient underwent grafting of 400?ml of autologous fat into the skin envelope and underlying pectoralis major muscle. Outcome was assessed by using a validated 3D laser scan technique for quantitative breast volume measurement. Other outcome measures included the BREAST-Q questionnaire and 2D clinical photography. At 12-month follow-up, the patient was observed to have maintenance of volume of the reconstructed breast. Her BREAST-Q scores were markedly improved compared with before fat grafting, and there was observable improvement in shape, contour, and symmetry on 2D clinical photography. The 2 new techniques, RoFA mastectomy and large-volume single-stage autologous fat grafting, were used in combination to achieve a satisfactory postmastectomy breast reconstruction. Novel tools for measurement of outcome were the 3D whole-body laser scanner and BREAST-Q questionnaire. This case demonstrates the potential for the use of fat grafting for reconstruction. Outcomes in a larger patient populations are needed to confirm these findings.

Fosh, Beverley; Watson, David I.; Yip, Jia Miin; Eaton, Michael; Smallman, Andrea; Dean, Nicola R.

2014-01-01

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Dermis fat grafting in contracted socket  

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Full Text Available 5 cases of severely contracted sockets were recon-structed with the use of dermis-fat graft. This type of graft is extremely useful as it is more viable and is a suitable replacement for soft tissue deficiency as in case of contracted socket. Excellent results were obtained and this method seems to be the method of choice in the manage-ment of such cases.

Betharia S

1988-01-01

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[Myringoplasty in children].  

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An anatomical success rate of 81% was obtained in 150 children 2 to 15 years of age operated upon by myringoplasty in the hospital Bretonneau, Paris between 1977 and 1984. Results were unrelated to age the season or the condition of the mucosa. Adverse factors were a previous history of a transtympanic aerator, a velar cleft or bilateral perforations. Mean functional gain after 1 year was 14 dB. It was not related to age or the technique used. PMID:4037618

François, M; Juvanon, J M; Contencin, P; Bobin, S; Manac'h, Y; Narcy, P

1985-01-01

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Success rate of myringoplasty at Groote Schuur Hospital  

Scientific Electronic Library Online (English)

Full Text Available SciELO South Africa | Language: English Abstract in english OBJECTIVES: The aim of this study was to determine the success rate of myringoplasty surgery performed at Groote Schuur Hospital and to evaluate some of the presumed prognostic factors. DESIGN: The study design was a retrospective analytical cohort. SETTING: Groote Schuur Hospital (tertiary medical [...] centre), Cape Town. SUBJECTS: This study assessed the success rate of 341 myringoplasty operations performed by surgeons in the Department of Otolaryngology from January 2005 to December 2009. OUTCOME MEASURES: An unsuccessful operation was classified as a residual perforation seen at the 3-month follow-up visit that remained present at all subsequent visits. Presumed prognostic factors such as the rank of the surgeon, size of the perforation, location of the perforation, graft used and whether it was a revision procedure, were also evaluated. Where possible, the audiometric gain following surgery was calculated. RESULTS: The overall success rate in terms of an intact tympanic membrane following myringoplasty was 71%. The average improvement in pure tone average following myringoplasty was 12.4 dB. In 64% of patients, socially acceptable hearing levels were present postoperatively (air-conduction of less than 30 dB). None of the presumed prognostic factors was a statistically significant determinant (p>0.05). CONCLUSION: The success rate for myringoplasty (in terms of perforation closure) of 71% at Groote Schuur Hospital compares well with that quoted in the literature. There is no ethical dilemma from a surgical outcomes perspective of registrars performing myringoplasties.

Juanita, Becker; Darlene, Lubbe.

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Structural fat grafting: more than a permanent filler.  

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Grafted fat has many attributes of an ideal filler, but the results, like those of any procedure, are technique dependent. Fat grafting remains shrouded in the stigma of variable results experienced by most plastic surgeons when they first graft fat. However, many who originally reported failure eventually report success after altering their methods of harvesting, refinement, and placement. Many surgeons have refined their techniques to obtain long-term survival and volume replacement with grafted fat. They have observed that transplanted fat not only adjusts facial and body proportion but also improves surrounding tissues into which the fat is placed. They have noted not only the improvement in the quality of aging skin and scars but also a remarkable improvement in conditions such as radiation damage, chronic ulceration, breast capsular contracture, and damaged vocal cords. The mechanism of fat graft survival is not clear, and the role of adipose-derived stem cells and preadipocytes in fat survival remains to be determined. Early research has indicated the possible involvement of more undifferentiated cells in some of the observed effects of fat grafting on surrounding tissues. Of particular interest is the research that has pointed to the use of stem cells to repair and even to become bone, cartilage, muscle, blood vessels, nerves, and skin. Further studies are essential to understand grafted fat tissue. PMID:16936550

Coleman, Sydney R

2006-09-01

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A STUDY ON EFFICACY OF AUTOLOGOUS PLATELET RICH PLASMA IN MYRINGOPLASTY  

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Full Text Available Objective: To study the efficacy and advantage in using autologus platelet rich plasma during myringoplasty in closure of tympanic membrane perforation preventing the graft displacement, promoting quicker healing & improving overall outcome.Methods : Platelet rich plasma(PRP is an autologus platelet rich concentrate prepared from patients own blood with growth factors up to 8 times that of normal serum and its efficacy when used during myringoplasty is studied.50 patients with chronic otitis media inactive mucosal disease were randomly chosen and 25 of them was the study group and other 25 were the control group. Both group patients underwent myringoplasty and PRP was used in the study group and the results were evaluated.Results: In our study among 25 cases that underwent myringoplasty with use of platelet rich fibrin, 24 had complete tympanic membrane closure and only one failure has been noticed. In controls 5 out of 25 cases had failure. The graft take up rate in our study is comparable with the reference studies. Use of PRP accelerates graft uptake.Conclusion: Platelet rich plasma is a cheap and cost effective platelet concentrate with enriched growth factors. It accelerates the tympanic membrane closure following myringoplasty.

Sankaranarayanan Gopalakrishnan

2013-06-01

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Free epidural fat-grafting after lumbar laminectomy using MRI  

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Free epidural fat-grafting was performed to prevent adhesion between scar tissue of the epidural space and dura and nerve root after lumbar laminectomy. The results were evaluated using MRI. Fifteen cases were operated upon with an average follow-up period of 7.5 months. MRI was recorded and the findings were classified into four types as follow: I, equally high signal case; II, slight fibrosis case; III, severe fibrosis case; IV, high signal disappeared case. The results showed 3 cases of type I, 7 cases of type II, 3 cases of type III, and 2 cases of type IV. According to MRI findings, free epidural fat is supposed to be still viable and alive, although slightly fibroses but the dural side remains a high signal area. Free epidural fat-grafting was useful for preventing adhesion around the epidural space. There was high relationship to age and sex with regard to viability of the free fat graft. (author).

Ohtsubo, Yoshimasa; Fujita, Masaaki; Motokawa, Satoru; Nakamura, Satoshi; Narabayashi, Yoko (Nagasaki Chuo National Hospital (Japan))

1994-09-01

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Free epidural fat-grafting after lumbar laminectomy using MRI  

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Free epidural fat-grafting was performed to prevent adhesion between scar tissue of the epidural space and dura and nerve root after lumbar laminectomy. The results were evaluated using MRI. Fifteen cases were operated upon with an average follow-up period of 7.5 months. MRI was recorded and the findings were classified into four types as follow: I, equally high signal case; II, slight fibrosis case; III, severe fibrosis case; IV, high signal disappeared case. The results showed 3 cases of type I, 7 cases of type II, 3 cases of type III, and 2 cases of type IV. According to MRI findings, free epidural fat is supposed to be still viable and alive, although slightly fibroses but the dural side remains a high signal area. Free epidural fat-grafting was useful for preventing adhesion around the epidural space. There was high relationship to age and sex with regard to viability of the free fat graft. (author)

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Autologous Fat Graft in the Reconstructed Breast: Fat Absorption Rate and Safety based on Sonographic Identification  

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Background Autologous fat graft has become a useful technique for correction of acquired contour deformity in reconstructed breasts. However, there remains controversial regarding the efficacy and safety of the practice for reconstructive breast surgery. Methods A retrospective review was performed on 102 patients who had secondary fat grafting after breast reconstruction. Fat harvest, refinement and injection were done by Coleman's technique. All patients were followed up postoperatively within 1 month and after 6 months including physical examination and ultrasonography. In 38 patients, the reabsorption rate was calculated by serial changes of thickness between skin and pectoral fascia in the ultrasonic finding. Locoregional recurrence rate was compared with control group of 449 patients who had breast reconstruction without fat graft in the same time period. Results Average 49.3 mL fat was injected into each breast. The most common location of fat graft was upper pole, followed by axilla, lower and medial breasts. During 28.7 months of average follow-up period, 2.9% of total patients had symptoms of palpable mass on fat graft side and ultrasonography identified fat necrosis and cyst formation in 17.6% of the patients. Calculated fat reabsorption rate was 32.9%. Locoregional recurrence was occurred in 1 patient (0.9%) and the rate was not different significantly with control group (2%). Conclusions Although further studies are required to provide surgeons with definitive guidelines for the implementation of fat grafting, we propose autologous fat graft is an efficient and safe technique for secondary breast reconstruction.

Kim, Hong Youl; Jung, Bok Ki; Lew, Dae Hyun

2014-01-01

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Myringoplasty with and without Cortical Mastoidectomy in Treatment of Non-cholesteatomatous Chronic Otitis Media: A Comparative Study  

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OBJECTIVE To compare the outcome and success of repair of uncomplicated tympanic membrane perforations with myringoplasty alone and when combined with mastoidectomy. METHODS A prospective study where 40 patients with non-cholesteatomatous chronic suppurative otitis media (CSOM) were recruited during the period of June 2013 to December 2013 from the outpatient clinic of Otorhinolaryngology department, Faculty of medicine, Cairo University. Patients were managed medically and after dryness of their perforations they were operated upon. Twenty patients underwent simple myringoplasty alone and 20 patients underwent myringoplasty with cortical mastoidectomy. Underlay technique with temporalis fascia was done for all patients. Follow-up period was at least 3 months. RESULTS Hearing improvement was comparable in both groups. There was no significant difference in graft uptake between the myringoplasty alone group (70%) and cortical mastoidectomy group (80%) (P = 0.7). There was no significant difference in ear dryness between the myringoplasty alone group (75%) and cortical mastoidectomy group (90%) (P = 0.4). CONCLUSION Mastoidectomy performed in non-cholesteatomatous CSOM in this study gives no statistically significant benefit over simple myringoplasty as regards graft success rate and dryness of the middle ear with comparable hearing outcome. PMID:25187749

Mohammed Abdel Tawab, Hazem; Mahmoud Gharib, Fadi; Algarf, Tareq M; ElSharkawy, Louay S

2014-01-01

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Lipoenxertia em reconstrução mamária / Fat grafting in breast reconstruction  

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Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese INTRODUÇÃO: Frequentemente, a reconstrução mamária requer um segundo tempo cirúrgico para corrigir visíveis irregularidades no contorno da mama. A lipoenxertia constitui-se em uma técnica cirúrgica que pode melhorar ou corrigir essas deformidades em substituição a outras técnicas convencionais de ma [...] ior morbidade ou complexidade. O objetivo deste estudo é demonstrar um método de correção de defeitos de contorno de mamas reconstruídas previamente pelas técnicas convencionais com enxerto de gordura, após 8 anos de experiência. MÉTODO: Todas as pacientes incluídas neste estudo foram previamente submetidas a mastectomia (total ou parcial) e a algum tipo de reconstrução mamária. A gordura foi obtida por meio de método clássico de lipoaspiração com seringa, delicadamente lavada com solução salina em uma peneira de aço inoxidável, decantada em uma seringa de 60 cc e enxertada após alguns minutos. RESULTADOS: Foram operadas 112 pacientes no período de 2005 a 2012. Houve 1 (8,9%) caso de perda total do enxerto de gordura, 22 (19,6%) pacientes apresentaram pequenos nódulos palpáveis, o volume médio enxertado foi de 100 cc e foram necessários múltiplos procedimentos para se alcançar o volume desejado. CONCLUSÕES: A lipoenxertia constitui-se em uma técnica segura, com baixa morbidade e altos índices de satisfação do cirurgião e das pacientes, apesar de necessitar de múltiplos procedimentos cirúrgicos para atingir bom resultado. Abstract in english BACKGROUND: Breast reconstruction often requires a second surgical procedure to correct visible irregularities of the breast contour. Lipofilling (fat grafting) consists of a surgical technique that improves or corrects such deformities, and serves as an alternative to other conventional techniques [...] that have higher morbidity rates and complexity. In the present study, we aimed to describe our 8-year experience with a fat grafting method for correcting contour deformities of breasts that were previously reconstructed using conventional techniques. METHODS: All patients in this study previously underwent mastectomy (total or partial) and some degree of breast reconstruction. The fat was obtained by liposuction using a syringe, and was gently rinsed with a saline solution in a stainless steel sieve, poured into a 60 cc syringe, and grafted after a few minutes. RESULTS: In total, 112 patients underwent surgery between 2005 and 2012. There was one (8.9%) case of total loss of the fat graft, while 22 (19.6%) patients had small palpable nodules. The average graft volume was 100 cc, and multiple procedures were required to achieve the desired volume. CONCLUSIONS: Fat grafting is a safe technique with low morbidity rates that demonstrates high surgeon and patient satisfaction levels, despite the need for multiple procedures to achieve good results.

Francisco José Fontenele, Bezerra; Rosely Moraes Gonçalves de, Moura; José Dalvo, Maia Neto.

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Facial fat grafting with a prototype injection control device  

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Full Text Available Hugh E Hetherington,1 Jon E Block2 1Bozeman Deaconess Health Group, Bozeman, MT, USA; 2The Jon Block Group, San Francisco, CA, USA Objective: To evaluate the initial clinical performance of a prototype injection control device (ICD to facilitate fat grafting by injection. Methods: An ICD, which mechanically couples the act of withdrawing the cannula with the act of depressing the plunger, was fabricated for the purpose of facial fat grafting. The action of the device results in deposition of consistent threads of fat having a volume of approximately 33 uL per cm that the cannula is withdrawn, which is slightly less than the internal volume of a 12-gauge cannula. A total of 26 patients underwent 30 procedures, and the results were subjectively evaluated using pre- and postoperative photographs, with a minimum follow-up of 4 months. Results: The desired degree of correction was more consistent, recovery was faster, and procedural efficiency was improved when performing the procedure with the ICD compared to historical use of the manual method of injection. Minor irregularities were the only complications encountered. Conclusion: The ICD optimally distributes fat as a uniform thread along the withdrawal tract of the cannula, thereby eliminating clumping and minimizing tissue trauma, resulting in reduced recovery time as well as more consistent and predictable clinical results. Since the ICD automates the injection process, it provides a notable and easily attainable efficiency in procedural time and minimal learning curve for the user. Keywords: dermal fillers, liposuction, facial rejuvenation, threading

Hetherington HE

2013-09-01

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Autologous fat grafting: use of closed syringe microcannula system for enhanced autologous structural grafting  

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Full Text Available Robert W Alexander,1 David Harrell2 1Department of Surgery, School of Medicine and Dentistry, University of Washington, Seattle, WA, USA; 2Harvest-Terumo Inc, Plymouth, MA, USA Objectives: Provide background for use of acquiring autologous adipose tissue as a tissue graft and source of adult progenitor cells for use in cosmetic plastic surgery. Discuss the background and mechanisms of action of closed syringe vacuum lipoaspiration, with emphasis on accessing adipose-derived mesenchymal/stromal cells and the stromal vascular fraction (SVF for use in aesthetic, structural reconstruction and regenerative applications. Explain a proven protocol for acquiring high-quality autologous fat grafts (AFG with use of disposable, microcannula systems. Design: Explain the components and advantage of use of the patented super luer-lock and microcannulas system for use with the closed-syringe system. A sequential explanation of equipment selection for minimally traumatic lipoaspiration in small volumes is presented, including use of blunt injection cannulas to reduce risk of embolism. Results: Thousands of AFG have proven safe and efficacious for lipoaspiration techniques for large and small structural fat grafting procedures. The importance and advantages of gentle harvesting of the adipose tissue complex has become very clear in the past 5 years. The closed-syringe system offers a minimally invasive, gentle system with which to mobilize subdermal fat tissues in a suspension form. Resulting total nuclear counting of undifferentiated cells of the adipose-derived -SVF suggests that the yield achieved is better than use of always-on, constant mechanical pump applied vacuum systems. Conclusion: Use of a closed-syringe lipoaspiration system featuring disposable microcannulas offers a safe and effective means of harvesting small volumes of nonmanipulated adipose tissues and its accompanying progenitor cells within the SVF. Closed syringes and microcannulas are available as safe, sterile, disposable, compact systems for acquiring high-quality AFG. Presented is a detailed, step-by-step, proven protocol for performing quality autologous structural adipose transplantation. Keywords: autologous fat grafting, closed syringe lipoaspiration, adipose-derived adult stem-stromal cell, bioscaffolds, lipoaspiration/liposuction, stromal vascular fraction (SVF

Alexander RW

2013-04-01

 
 
 
 
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Fat grafting to the breast and adipose-derived stem cells: recent scientific consensus and controversy.  

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Recent technical advances in fat grafting and the development of surgical devices such as liposuction cannulae have made fat grafting a relatively safe and effective procedure. However, new guidelines issued by the American Society of Plastic Surgeons in 2009 announced that fat grafting to the breast is not a strongly recommended procedure, as there are limited scientific data on the safety and efficacy of this particular type of fat transfer. Recent progress by several groups has revealed that multipotent adult stem cells are present in human adipose tissue. This cell population, termed adipose-derived stem cells (ADSC), represents a promising approach to future cell-based therapies, such as tissue engineering and regeneration. In fact, several reports have shown that ADSC play a pivotal role in graft survival through both adipogenesis and angiogenesis. Although tissue augmentation by fat grafting does have several advantages in that it is a noninvasive procedure and results in minimal scarring, it is essential that such a procedure be supported by evidence-based medicine and that further basic scientific and clinical research is conducted to ensure that fat grafting is a safe and effective procedure. PMID:20601560

Mizuno, Hiroshi; Hyakusoku, Hiko

2010-01-01

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Management of an irradiated anophthalmic socket following dermis-fat graft rejection: A case report  

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Dermis-fat graft (DFG) is often the only promising option in cases of severely contracted sockets. However, there is an increased risk of graft failure in irradiated sockets with decreased vascularity. In such difficult cases, repeat DFG implantation also has higher risks of graft failure. We describe an ingenious method of successful management of an irradiated anophthalmic socket following DFG infection and necrosis, with acceptable cosmetic results. At surgery, an orbital impression was ta...

Raizada Kuldeep; Shome Debraj; Honavar Santosh

2008-01-01

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Soft tissue augmentation with autologous fat graft: The dissected pouch technique  

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Full Text Available Background: Soft tissue augmentation with autologous fat graft has been increasingly used by plastic surgeons despite unpredictable results. Several techniques have been described to prevent the main setback of this technique, fat graft resorption. However, there is no ideal technique described for this purpose. Materials and Methods: Twenty patients with subcutaneous tissue loss, atrophy or hypoplasia were treated with lipofilling. A subcutaneous pouch is dissected at the deformed area and later it is filled with autologous fat graft. Results: Graft maintenance during the postoperative period was satisfactory. Overcorrection was not performed except for the first three cases. Patient, surgeon and layman satisfaction was surveyed. Satisfaction was rated between 0 and 10. The mean score was 7.67 ± 1.22. Conclusion: The authors describe a technique for soft tissue augmentation which effectively corrects contour deformities, provides a low resorption rate and a relatively non-visible scar without causing irregularities.

Livaoglu Murat

2009-01-01

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Importance of mesenchymal stem cells in autologous fat grafting: a systematic review of existing studies.  

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Autologous fat grafting (lipofilling) enables repair and augmentation of soft tissues and is increasingly used both in aesthetic and reconstructive surgery. Autologous fat has several advantages, including biocompatibility, versatility, natural appearance, and low donor site morbidity. The main limitation is unpredictable graft resorption, which ranges from 25%-80%, probably as a result of ischaemia and lack of neoangiogenesis. To obviate these disadvantages, several studies have searched for new ways of increasing the viability of the transplanted tissue. One promising approach has been to enrich the fat graft with adipose tissue-derived mesenchymal stem cells (ASC) before transplantation. We have reviewed original studies published on fat transplantation enriched with ASC. We found four murine and three human studies that investigated the subject after a sensitive search of publications. In the human studies, so-called cell assisted lipotransfer (CAL) increased the ASC concentration 2-5 times compared with non-manipulated fat grafts, which caused a questionable improvement in survival of fat grafts, compared with that of traditional lipofilling. In contrast, in two of the murine studies ASC-concentrations were increased 1250 and 6250 times, respectively, by ASC ex vivo expansion, which resulted in considerably improved fat transplant survival as well as quality. This effect of high-level enrichment with ASC is thought to have been caused by paracrine signalling, cellular differentiation, or both. The surgical and tissue handling techniques used in lipofilling are well proved, but the added effect of high-level enrichment with ex vivo expanded ASC still needs to be investigated properly in human lipofilling studies, combined with a thorough follow up and matched control groups. In conclusion, ASC-enriched lipofilling theoretically has the potential for transforming lipofilling from a relatively unpredictable intervention into one in which the resorption rate, quality of tissue, and safety can be predicted, and possibly superior to prosthetic implantation. PMID:22471250

Trojahn Kølle, Stig-Frederik; Oliveri, Roberto S; Glovinski, Peter Viktor; Elberg, Jens Jørgen; Fischer-Nielsen, Anne; Drzewiecki, Krzysztof Tadeusz

2012-04-01

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Importance of mesenchymal stem cells in autologous fat grafting : a systematic review of existing studies  

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Autologous fat grafting (lipofilling) enables repair and augmentation of soft tissues and is increasingly used both in aesthetic and reconstructive surgery. Autologous fat has several advantages, including biocompatibility, versatility, natural appearance, and low donor site morbidity. The main limitation is unpredictable graft resorption, which ranges from 25%-80%, probably as a result of ischaemia and lack of neoangiogenesis. To obviate these disadvantages, several studies have searched for new ways of increasing the viability of the transplanted tissue. One promising approach has been to enrich the fat graft with adipose tissue-derived mesenchymal stem cells (ASC) before transplantation. We have reviewed original studies published on fat transplantation enriched with ASC. We found four murine and three human studies that investigated the subject after a sensitive search of publications. In the human studies, so-called cell assisted lipotransfer (CAL) increased the ASC concentration 2-5 times compared with non-manipulated fat grafts, which caused a questionable improvement in survival of fat grafts, compared with that of traditional lipofilling. In contrast, in two of the murine studies ASC-concentrations were increased 1250 and 6250 times, respectively, by ASC ex vivo expansion, which resulted in considerably improved fat transplant survival as well as quality. This effect of high-level enrichment with ASC is thought to have been caused by paracrine signalling, cellular differentiation, or both. The surgical and tissue handling techniques used in lipofilling are well proved, but the added effect of high-level enrichment with ex vivo expanded ASC still needs to be investigated properly in human lipofilling studies, combined with a thorough follow up and matched control groups. In conclusion, ASC-enriched lipofilling theoretically has the potential for transforming lipofilling from a relatively unpredictable intervention into one in which the resorption rate, quality of tissue, and safety can be predicted, and possibly superior to prosthetic implantation.

Trojahn KØlle, Stig-Frederik; Oliveri, Roberto S

2012-01-01

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Fat grafting versus adipose-derived stem cell therapy: distinguishing indications, techniques, and outcomes.  

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With adipose-derived stem cells (ASCs) at the forefront of research and potential clinical applications, it is important that clinicians be able to distinguish them from the fat grafting currently used clinically and to understand how the two approaches relate to one another. At times, there has been confusion in clinically considering the two therapies to be the same. This report is aimed at distinguishing clearly between fat grafting and ASC therapy with regard to the indications, harvesting, processing, application techniques, outcomes, and complications. Findings have shown that autologous fat transfer, a widely used procedure for soft tissue augmentation, is beneficial for reconstructive and cosmetic procedures used to treat patients with volume loss due to disease, trauma, congenital defects, or the natural process of aging. On the other hand, ASCs have been identified as an ideal source of cells for regenerative medicine, with the potential to serve as soft tissue therapy for irradiated, scarred, or chronic wounds. Recent advances in tissue engineering suggest that the supplementation of fat grafts with ASCs isolated in the stromal vascular fraction may increase the longevity and quality of the fat graft. Research suggests that ASC supplementation may be a great clinical tool in the future, but more data should be acquired before clinical applications. PMID:22069062

Tabit, Christina J; Slack, Ginger C; Fan, Kenneth; Wan, Derrick C; Bradley, James P

2012-06-01

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[CT image of a free fat graft (FFG) within hemilaminectomy space (author's transl)].  

Science.gov (United States)

To prevent scarformation after hemilaminectomy many authors (1, 2, 6, 8) use free autologous fat grafts. CT scanning reveals vitality or death if the transplant. CT enables to control intra vitam whether FFG diminishes postnucleotomy syndrome caused by scar formation. PMID:7080628

Schroeder, S; Lackner, K; Köster, O; Anders, G

1982-02-01

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Application of fascia of the temporal muscle and cartilage of the auricular tragus in myringoplasty in children  

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Full Text Available Introduction. Perforation of the tympanic membrane in children may be the cause of recurrent middle ear infection and loss of hearing. Objective. The aim of this study was to analyze the application of different reconstructive materials in surgical technique myringoplasty. Methods. We performed 88 myringoplasties due to auricular tragus perforation in 76 children (aged 4 to 16 years, mean 11.9 years from July 2001 to July 2009. Age, gender, size and the site of perforation, status of the contra lateral ear, underlying cause of the perforations, surgical technique, preoperative and postoperative hearing levels and postoperative complications were recorded and analyzed. In performing myringoplasty we used fascia of the temporal muscle and cartilage of the auricular tragus. Results. In 43 (48% patients we used fascia of the temporal muscle and in 45 (52% cartilage of the auricular tragus. Graft success was defined as an intact eardrum at 12 months postoperatively and improvement in the perception of air-bone gap of 10 dB, which we recorded in 73 (83% cases. Re-perforations were recorded in 12 (13% patients, of whom in 8 (18.6% cases we used the temporal fascia and in 4 (9.3% cases a tragal cartilage. Retraction of the tympanic membrane was recorded in 3 (4% cases with the temporal fascia. Conclusion. Myringoplasty is a reasonably successful method with good functional results in pediatric patients. Risk factors of surgical failure are young age, the size of auricular tragus perforation and pathological conditions of the contra lateral ear. The tragal cartilage gives better results in cases with bilateral perforations because the possibility of retractions and re-perforations is lower. Relatively small number of patients is probably the reason that, except for young age, differences between the two groups did not reach the level of statistical significance.

Baljoševi? Ivan

2012-01-01

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Oncological safety of autologous fat grafting after breast conservative treatment: a prospective evaluation.  

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Autologous fat graft to the breast is a useful tool to correct defects after breast conservative treatment (BCT). Although this procedure gains popularity, little is known about the interaction between the fat graft and the prior oncological environment. Evidences of safety of this procedure in healthy breast and after post-mastectomy reconstruction exist. However, there is paucity of data among patients who underwent BCT which are hypothetically under a higher risk of local recurrence (LR). Fifty-nine patients, with prior BCT, underwent 75 autologous fat graft procedures using the Coleman's technique, between October 2005 and July 2008. Follow-up was made by clinical and radiologic examination at least once, after 6 months of the procedure. Mean age was 50 ± 8.5 years, and mean follow-up was 34.4 ± 15.3 months. Mean time from oncological surgery to the first fat grafting procedure was 76.6 ± 30.9 months. Most of patients were at initial stage 0 (11.8%), I (33.8%), or IIA (23.7%). Immediate complication was observed in three cases (4%). Only three cases of true LR (4%) associated with the procedure were observed during the follow-up. Abnormal breast images were present in 20% of the postoperative mammograms, and in 8% of the cases, biopsy was warranted. Autologous fat graft is a safe procedure to correct breast defects after BCT, with low postoperative complications. Although it was not associated with increased risk of LR in the group of patients studied, prospective trials are needed to certify that it does not interfere in patient's oncological prognosis. PMID:24450421

Brenelli, Fabricio; Rietjens, Mario; De Lorenzi, Francesca; Pinto-Neto, Aarão; Rossetto, Fabio; Martella, Stefano; Rodrigues, José R P; Barbalho, Daniel

2014-01-01

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Lymphedema Fat Graft: An Ideal Filler for Facial Rejuvenation  

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Lymphedema is a chronic disorder characterized by lymph stasis in the subcutaneous tissue. Lymphatic fluid contains several components including hyaluronic acid and has many important properties. Over the past few years, significant research has been performed to identify an ideal tissue to implant as a filler. Because of its unique composition, fat harvested from the lymphedema tissue is an interesting topic for investigation and has significant potential for application as a filler, particularly in facial rejuvenation. Over a 36-month period, we treated and assessed 8 patients with lymphedematous limbs who concurrently underwent facial rejuvenation with lymphedema fat (LF). We conducted a pre- and post-operative satisfaction questionnaire survey and a histological assessment of the harvested LF fat. The overall mean general appearance score at an average of 6 months after the procedure was 7.2±0.5, demonstrating great improvement. Patients reported significant improvement in their skin texture with a reading of 8.5±0.7 and an improvement in their self-esteem. This study demonstrates that LF as an ideal autologous injectable filler is clinically applicable and easily available in patients with lymphedema. We recommend the further study and clinical use of this tissue as it exhibits important properties and qualities for future applications and research. PMID:25276654

Nicoli, Fabio; Chilgar, Ram M.; Sapountzis, Stamatis; Lazzeri, Davide; Sze Wei, Matthew Yeo; Ciudad, Pedro; Nicoli, Marzia; Lim, Seong Yoon; Chen, Pei-Yu; Constantinides, Joannis

2014-01-01

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Outcomes of structural fat grafting for paralytic and non-paralytic dysphonia.  

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Aims of this prospective study were to evaluate the results of vocal fold structural fat grafting for glottic insufficiency and to compare the outcomes obtained in unilateral vocal fold paralysis (UVFP) and congenital or acquired soft tissue defects in vocal folds. Sixty-six consecutive patients with breathy dysphonia, in 43 cases (aged 16-79 years) related to UVFP and in 23 cases (aged 16-67 years) related to vocal fold iatrogenic scar or sulcus vocalis, underwent autologous structural fat grafting into vocal folds. Lipoaspirates were centrifuged at 1200 g for 3 min to separate and remove blood, cell debris and the oily layer. The refined fat was injected under direct microlaryngoscopy in a multilayered way. The main outcome measures were grade, roughness, breathiness, asthenicity and strain (GRBAS) perceptual evaluation, maximum phonation time (MPT), self-assessed Voice Handicap Index (VHI), and voice acoustic analysis, considered pre-operatively and at 3 and 6 months after fat grafting. After surgery, MPT, VHI, G and B improved in both groups (p < 0.05). In particular, G and VHI functional subscales showed a significantly greater decrease in patients with UVFP (p < 0.05). The acoustic variables improved significantly only in the UVFP group (p < 0.005). From 3 to 6 months postoperatively, most variables showed a trend with further improvement. Vocal fold structural fat grafting was significantly effective in treating glottic insufficiency due to UVFP or soft tissue defects. Perceptual, acoustic and subjective assessments confirmed that patients with UVFP had better outcomes than those with soft tissue defects. PMID:22064781

Cantarella, G; Baracca, G; Forti, S; Gaffuri, M; Mazzola, R F

2011-06-01

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Lipoenxertia nas mamas: procedimento consagrado ou experimental? Breast fat grafting: experimental or established procedure?  

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Full Text Available Atualmente vem ocorrendo aumento da incidência de utilização de enxertia de gordura para correção de defeitos mamários congênitos ou adquiridos e para tratamento mamário estético. Esse aumento é decorrente do surgimento de novas técnicas de lipoenxertia, que produzem resultados mais duradouros e confiáveis, apesar da crença de alguns autores de que o procedimento possa dificultar o rastreamento do câncer mamário. Esta revisão de literatura tem como objetivo identificar as técnicas de lipoenxertia mamárias mais utilizadas, avaliá-las quanto à eficácia e à segurança, e relatar as principais complicações associadas. A revisão foi realizada nas bases de dados PubMed e LILACS, e os fatores de inclusão foram: artigos em idioma inglês, publicados nos últimos cinco anos. Como resultado observou-se aumento do número de trabalhos abordando o tema nos últimos anos, e predomínio de uma técnica de lipoenxertia específica. A maioria dos trabalhos demonstra que a lipoenxertia mamária não prejudica o rastreamento radiológico para câncer mamário, e alguns sugerem que a gordura enxertada potencializa o desenvolvimento de câncer nas mamas. Apesar do aumento do número de trabalhos, existem ainda poucos com bom nível de evidência científica. Esta revisão permitiu concluir que a lipoenxertia é uma técnica alternativa para reparação de defeitos mamários e discreto aumento estético das mamas, devendo ser utilizada por cirurgiões com treinamento adequado e acompanhada por equipe de radiologia experiente em imagenologia mamária. Mais trabalhos com metodologia científica adequada são necessários para avaliar a lipoenxertia mamária.There has recently been an increase in the use of fat grafting for the correction of congenital or acquired breast deformities and for aesthetic breast treatment. This increase is due to the emergence of novel fat grafting techniques that produce lasting and reliable results despite some authors' beliefs that the procedure might hinder breast cancer screening. This literature review aims to identify the most frequently used breast fat grafting techniques, evaluate their efficacy and safety, and report their major complications. The review was performed after a search in the PubMed and LILACS databases, and only English-language articles published over the past 5 years were assessed. There have been an increased number of studies on the topic in recent years, and a specific fat grafting technique has been primarily reported. Most studies in this area have shown that breast fat grafting does not affect radiological breast cancer screening, whereas some studies have suggested that the use of grafted fat may enhance the development of breast cancer. Despite the increased number of published studies, few have a good level of scientific evidence. This review concludes that fat grafting is an alternative technique for the correction of breast deformities and moderate aesthetic breast enlargement and should be performed by properly trained surgeons accompanied by a radiology team that is experienced in breast imaging. Further studies with appropriate scientific methodologies are needed to evaluate breast fat grafting.

Alexandre Roriz Blumenschein

2012-12-01

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Selective Augmentation of Stem Cell Populations in Structural Fat Grafts for Maxillofacial Surgery  

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Structural fat grafting utilizes the centrifugation of liposuction aspirates to create a graded density of adipose tissue. This study was performed to qualitatively investigate the effects of centrifugation on stem cells present in adipose tissue. Liposuction aspirates were obtained from healthy donors and either not centrifuged or centrifuged at 1,800 rpm for 3 minutes. The obtained fat volumes were divided into three layers and then analyzed. The results demonstrate that centrifugation induces a different distribution of stem cells in the three layers. The high-density layer displays the highest expression of mesenchymal stem cell and endothelial markers. The low-density layer exhibits an enrichment of multipotent stem cells. We conclude that appropriate centrifugation concentrates stem cells. This finding may influence the clinical practice of liposuction aspirate centrifugation and enhance graft uptake. PMID:25375632

Gardin, Chiara; Tieghi, Riccardo; Galie, Manlio; Elia, Giovanni; Piattelli, Adriano; Pinton, Paolo; Bressan, Eriberto; Zavan, Barbara

2014-01-01

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Coronoidectomy, masticatory myotomy and buccal fat pad graft in management of advanced oral submucous fibrosis.  

Science.gov (United States)

The purpose of this study is to evaluate coronoidectomy, masticatory myotomy and buccal fat pad graft in advanced (Stage III-IV) oral sub mucous fibrosis (OSF). 10 patients with clinically and histologically confirmed advanced OSF underwent surgery entailing bilateral coronoidectomy, masticatory muscle myotomy and closure with a pedicled buccal fat pad graft followed by vigorous mouth opening exercises. The result was evaluated using the interincisal distance at maximum mouth opening as the objective outcome measure over a follow up period of 12 months. Results showed a mean interincisal opening of 14.7 mm preoperatively and 32.5 mm at 12 months postoperatively. Relapse was encountered in one patient who did not cooperate with the postoperative exercise regime. Results suggest this regime is effective. PMID:22551649

Kothari, M C; Hallur, N; Sikkerimath, B; Gudi, S; Kothari, C R

2012-11-01

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Lipoenxertia nas mamas: procedimento consagrado ou experimental? / Breast fat grafting: experimental or established procedure?  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Atualmente vem ocorrendo aumento da incidência de utilização de enxertia de gordura para correção de defeitos mamários congênitos ou adquiridos e para tratamento mamário estético. Esse aumento é decorrente do surgimento de novas técnicas de lipoenxertia, que produzem resultados mais duradouros e con [...] fiáveis, apesar da crença de alguns autores de que o procedimento possa dificultar o rastreamento do câncer mamário. Esta revisão de literatura tem como objetivo identificar as técnicas de lipoenxertia mamárias mais utilizadas, avaliá-las quanto à eficácia e à segurança, e relatar as principais complicações associadas. A revisão foi realizada nas bases de dados PubMed e LILACS, e os fatores de inclusão foram: artigos em idioma inglês, publicados nos últimos cinco anos. Como resultado observou-se aumento do número de trabalhos abordando o tema nos últimos anos, e predomínio de uma técnica de lipoenxertia específica. A maioria dos trabalhos demonstra que a lipoenxertia mamária não prejudica o rastreamento radiológico para câncer mamário, e alguns sugerem que a gordura enxertada potencializa o desenvolvimento de câncer nas mamas. Apesar do aumento do número de trabalhos, existem ainda poucos com bom nível de evidência científica. Esta revisão permitiu concluir que a lipoenxertia é uma técnica alternativa para reparação de defeitos mamários e discreto aumento estético das mamas, devendo ser utilizada por cirurgiões com treinamento adequado e acompanhada por equipe de radiologia experiente em imagenologia mamária. Mais trabalhos com metodologia científica adequada são necessários para avaliar a lipoenxertia mamária. Abstract in english There has recently been an increase in the use of fat grafting for the correction of congenital or acquired breast deformities and for aesthetic breast treatment. This increase is due to the emergence of novel fat grafting techniques that produce lasting and reliable results despite some authors' be [...] liefs that the procedure might hinder breast cancer screening. This literature review aims to identify the most frequently used breast fat grafting techniques, evaluate their efficacy and safety, and report their major complications. The review was performed after a search in the PubMed and LILACS databases, and only English-language articles published over the past 5 years were assessed. There have been an increased number of studies on the topic in recent years, and a specific fat grafting technique has been primarily reported. Most studies in this area have shown that breast fat grafting does not affect radiological breast cancer screening, whereas some studies have suggested that the use of grafted fat may enhance the development of breast cancer. Despite the increased number of published studies, few have a good level of scientific evidence. This review concludes that fat grafting is an alternative technique for the correction of breast deformities and moderate aesthetic breast enlargement and should be performed by properly trained surgeons accompanied by a radiology team that is experienced in breast imaging. Further studies with appropriate scientific methodologies are needed to evaluate breast fat grafting.

Alexandre Roriz, Blumenschein; Ruffo, Freitas-Junior; Andrea Thomazine, Tuffanin; Danielle Isadora, Blumenschein.

2012-12-01

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Breast reconstruction de novo by water-jet assisted autologous fat grafting – a retrospective study  

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Full Text Available [english] Background: Autologous fat grafting has become a frequent, simple, reproducible and low-risk technique for revisional or partial breast reconstruction. The presented European multicenter study describes an optimized treatment and follow-up protocol for the de novo breast reconstruction after total mastectomy by lipotransfer alone.Methods: A retrospective European multicenter trial included 135 procedures on 28 (35 breasts postmastectomy patients (mean 52.4 years. All women were treated with the water-jet assisted fat grafting method (BEAULI™ combined with additional procedures (NAC reconstruction, contralateral mastoplasty and evaluated with at least 6 months follow-up (mean 2.6 years. Sonography or mammography, clinical examination, patient questionnaire (10-point Likert scale and digital photographs were carried out.Results: On average the patients received 4 to 6 procedures each with a single volume of 159 ml (±61 ml over 21 months (range 9 months to 2.5 years. In total 1,020 ml (±515 ml fat were grafted till a complete breast reconstruction was achieved. Irradiated patients needed a significantly higher volume than non-irradiated (p<0.041. Main treatment complications were liponecrosis (2.59%, infection (0.74% and granuloma (0.74%. Patient satisfaction was overall high to very high (96% and confirmed the good aesthetic results (68% and the natural softness, contour and shape of the reconstructed breast.Conclusions: A complete breast reconstruction with large volume fat grafting is alternatively possible to standard techniques in selected cases. It takes at least 4 to 6 lipotransfers in the course of 2 years. Patients with prior radiotherapy may require even up to 8 sessions over nearly 3 years of treatment.

Hoppe, Delia Letizia

2013-12-01

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Management of an irradiated anophthalmic socket following dermis-fat graft rejection: A case report  

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Full Text Available Dermis-fat graft (DFG is often the only promising option in cases of severely contracted sockets. However, there is an increased risk of graft failure in irradiated sockets with decreased vascularity. In such difficult cases, repeat DFG implantation also has higher risks of graft failure. We describe an ingenious method of successful management of an irradiated anophthalmic socket following DFG infection and necrosis, with acceptable cosmetic results. At surgery, an orbital impression was taken with ophthalmic grade alginate. Based on this measurement, a custom-made stem pressure socket-expander made up of high density polymethyl methacrylate (PMMA was fitted, a week post surgery and kept in situ for six weeks. On review, the fornices had considerably deepened. The expander device was removed and the patient was now fitted with a custom-made thicker prosthesis made up of high-density PMMA. The patient has followed up for a year subsequently and the prosthesis has remained stable.

Raizada Kuldeep

2008-01-01

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Myringoplasty in children: retrospective analysis of 35 cases Miringoplastia em crianças: análise retrospectiva de 35 casos  

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Full Text Available AIMS: to carry out a retrospective analysis of myringoplasty results in children in our institute. MATERIALS AND METHODS:Thirty five children, 9 to 14 years old, who underwent myringoplasty in our hospital between April 2002 and May 2004, formed the study group. Data regarding successful perforation closure, factors influencing success rates and hearing improvement were recorded. RESULTS: Closure of perforation was successful in 30 (85.7% of the 35 patients. Graft take failure occurred in 5 patients. Audiological improvement was seen in 27 (77% patients, out of which 23 cases had 10-15 db and 4 cases had 15-20 db air-bone gap. Hearing was found to be worse postoperatively in 3 patients, while no change was noted in the remaining 5 patients. There was no case of profound hearing loss. CONCLUSION: Myringoplasty is a beneficial procedure in the pediatric population in the hands of a skilled and experienced surgeons. If performed properly, it has a good chance of restoring a child's hearing. However, a large study with a long follow up is warranted in order to come to a definitive conclusion.OBJETIVOS: fazer uma análise retrospectiva dos resultados de miringoplastia em crianças em nosso instituto. MATERIAIS E MÉTODOS: Trinta e cinco crianças com idades entre 9 e 14 anos, que sofreram miringoplastia em nosso hospital, entre abril de 2002 e maio de 2004 formaram o Grupo de Estudo. Registramos os dados relacionados a fechamento bemsucedido da perfuração, fatores que influenciaram a taxa de sucesso e melhorias na audição. RESULTADOS: O fechamento bem-sucedido da perfuração ocorreu em 30 (85,7% dos 35 pacientes. Falha na "pega" do enxerto ocorreu em 5 pacientes. A melhoria auditiva aconteceu em 27 (77% pacientes, dos quais 23 tiveram gap aéreo-ósseo entre 10-15 db e 4 tiveram esse gap entre 15-20 db. A audição pós-operatória piorou em 3 pacientes, e em 5 não houve alteração a esse respeito. Não houve casos de perda auditiva profunda. CONCLUSÃO: A miringoplastia é um procedimento benéfico na população pediátrica nas mãos de cirurgiões habilidosos e experientes. Se conduzida adequadamente, ela tem boas possibilidades de restaurar a audição da criança. Entretanto, precisamos ainda de um estudo maior, com acompanhamento mais longo para podermos chegar a uma conclusão mais definitiva.

Nemer Al-Khtoum

2009-06-01

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Myringoplasty in children: retrospective analysis of 35 cases / Miringoplastia em crianças: análise retrospectiva de 35 casos  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVOS: fazer uma análise retrospectiva dos resultados de miringoplastia em crianças em nosso instituto. MATERIAIS E MÉTODOS: Trinta e cinco crianças com idades entre 9 e 14 anos, que sofreram miringoplastia em nosso hospital, entre abril de 2002 e maio de 2004 formaram o Grupo de Estudo. Registr [...] amos os dados relacionados a fechamento bemsucedido da perfuração, fatores que influenciaram a taxa de sucesso e melhorias na audição. RESULTADOS: O fechamento bem-sucedido da perfuração ocorreu em 30 (85,7%) dos 35 pacientes. Falha na "pega" do enxerto ocorreu em 5 pacientes. A melhoria auditiva aconteceu em 27 (77%) pacientes, dos quais 23 tiveram gap aéreo-ósseo entre 10-15 db e 4 tiveram esse gap entre 15-20 db. A audição pós-operatória piorou em 3 pacientes, e em 5 não houve alteração a esse respeito. Não houve casos de perda auditiva profunda. CONCLUSÃO: A miringoplastia é um procedimento benéfico na população pediátrica nas mãos de cirurgiões habilidosos e experientes. Se conduzida adequadamente, ela tem boas possibilidades de restaurar a audição da criança. Entretanto, precisamos ainda de um estudo maior, com acompanhamento mais longo para podermos chegar a uma conclusão mais definitiva. Abstract in english AIMS: to carry out a retrospective analysis of myringoplasty results in children in our institute. MATERIALS AND METHODS:Thirty five children, 9 to 14 years old, who underwent myringoplasty in our hospital between April 2002 and May 2004, formed the study group. Data regarding successful perforation [...] closure, factors influencing success rates and hearing improvement were recorded. RESULTS: Closure of perforation was successful in 30 (85.7%) of the 35 patients. Graft take failure occurred in 5 patients. Audiological improvement was seen in 27 (77%) patients, out of which 23 cases had 10-15 db and 4 cases had 15-20 db air-bone gap. Hearing was found to be worse postoperatively in 3 patients, while no change was noted in the remaining 5 patients. There was no case of profound hearing loss. CONCLUSION: Myringoplasty is a beneficial procedure in the pediatric population in the hands of a skilled and experienced surgeons. If performed properly, it has a good chance of restoring a child's hearing. However, a large study with a long follow up is warranted in order to come to a definitive conclusion.

Nemer, Al-Khtoum; Mohammad Ali, Hiari.

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Evaluation of Healing Potential of Autogenous, Macroscopic Fat Deposited or Fat Free, Omental Graft in Experimental Radius Bone Defect in Rabbit: Radiological Study  

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Full Text Available This study was designed for evaluation of the difference between the ability of greater omentum graft with or without macroscopic fat deposition in acceleration of bone healing process. Adult female New Zealand white rabbits (n=15 were randomly divided into three equal groups. In groups A and B, the drilled hole on the left radius was filled by the omentum without and with macroscopic fat deposition, respectively while drilled hole on the right radius left intact for consideration as control. In group C, the drilled hole on the left and right radius was filled by the omentum sample with and without macroscopic fat deposition, respectively. Experimental bone defects on the radiuses were secured by the pieces of greater omentum, with or without macroscopic fat deposition, which obtained as an autogenous graft from each rabbit in accompany with control samples. Standardized serial radiography for evaluation of bone healing was performed and the difference in bone healing process in three groups of study was determined. According to the obtained data, the radius bones which filled by omentum without macroscopic fat deposition showed faster healing process than the radius bones which filled by omentum with macroscopic fat deposition (P<0.05.

Mohammad Nasrollahzadeh Masouleh, Iraj Sohrabi Haghdoost, Gholamreza Abedi Cham Heydari, Amirali Raissi* and Soroush Mohitmafi1

2011-01-01

 
 
 
 
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Evaluation of healing potential of autogenous, macroscopic fat deposited or fat free, omental graft in experimental radius bone defect in rabbit: Radiological study  

International Nuclear Information System (INIS)

This study was designed for evaluation of the difference between the ability of greater omentum graft with or without macroscopic fat deposition in acceleration of bone healing process. Adult female New Zealand white rabbits (n=15) were randomly divided into three equal groups. In groups A and B, the drilled hole on the left radius was filled by the omentum without and with macroscopic fat deposition, respectively while drilled hole on the right radius left intact for consideration as control. In group C, the drilled hole on the left and right radius was filled by the omentum sample with and without macroscopic fat deposition, respectively. Experimental bone defects on the radiuses were secured by the pieces of greater omentum, with or without macroscopic fat deposition, which obtained as an autogenous graft from each rabbit in accompany with control samples. Standardized serial radiography for evaluation of bone healing was performed and the difference in bone healing process in three groups of study was determined. According to the obtained data, the radius bones which filled by omentum without macroscopic fat deposition showed faster healing process than the radius bones which filled by omentum with macroscopic fat deposition (P<0.05). (author)

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The effects of free fat graft or cellulose membrane implants on laminectomy membrane formation in dogs.  

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The purpose of this study was to determine the effect of cellulose membrane or free fat grafts (FFG) on laminectomy membrane (LM) formation. Eighteen dogs were randomly divided into three groups of six dogs. All dogs underwent a modified dorsal laminectomy on T(13)-L(1). The laminectomy defect was left uncovered in the control group but either a FFG or a cellulose membrane implant was provided in the other two groups. The dogs were evaluated through neurological examination, myelography, macroscopic roundness index of spinal cord and histological evaluations of epidural fibrosis and spinal cord. The results showed a significant difference between the control and the FFG group, with the FFG causing neurological deficits and spinal cord compression as assessed by the roundness index of the spinal cord. Both FFG and cellulose membrane were partially effective in preventing LM formation. The use of FFG was associated with a high rate of significant neurological complications and spinal cord lesions. PMID:16624715

da Costa, Ronaldo C; Pippi, Ney L; Graça, Dominguita L; Fialho, Sérgio A; Alves, Aline; Groff, Ana C; Rezler, Ubiratã

2006-05-01

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Effect of an autogenous free fat graft on hemilaminectomy defects in dogs.  

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The purpose of this study was to evaluate the effect of an autogenous free fat graft (FFG) on hemilaminectomy defects. Hemilaminectomy was performed at three levels in three beagles, and each defect was designated as a control site or a site treated with one of two different sizes of FFG. Subsequently, longitudinal computed tomography scanning and histopathological examination were performed. As a result, no postoperative dural adhesion was recognized at the sites where FFGs were placed regardless of the size of the FFG. Moreover, there was no compression of the spinal cord by the FFG. Therefore, it appears that postoperative dural adhesion was controlled by the FFG and that the possibility of FFG migration into the spinal canal is low in hemilaminectomy. In conclusion, placement of an FFG over the defect was considered useful for preventing complications in hemilaminectomy. PMID:19887733

Shimizu, Junichiro; Koga, Maiko; Kishimoto, Miori; Lee, Ki-Ja; Iwasaki, Toshiroh; Miyake, Yoh-Ichi; Yamada, Kazutaka

2009-10-01

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Effect of an autogenous free fat graft on hemilaminectomy defects in dogs  

International Nuclear Information System (INIS)

The purpose of this study was to evaluate the effect of an autogenous free fat graft (FFG) on hemilaminectomy defects. Hemilaminectomy was performed at three levels in three beagles, and each defect was designated as a control site or a site treated with one of two different sizes of FFG. Subsequently, longitudinal computed tomography scanning and histopathological examination were performed. As a result, no postoperative dural adhesion was recognized at the sites where FFGs were placed regardless of the size of the FFG. Moreover, there was no compression of the spinal cord by the FFG. Therefore, it appears that postoperative dural adhesion was controlled by the FFG and that the possibility of FFG migration into the spinal canal is low in hemilaminectomy. In conclusion, placement of an FFG over the defect was considered useful for preventing complications in hemilaminectomy

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Supervivencia a largo plazo de los injertos grasos Long-term survival with fat grafting  

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Full Text Available Presentamos varios casos de pérdida de volumen de diferentes etiologías y en distintas regiones corporales y faciales tratadas mediante injertos de tejido graso autólogo según la técnica de lipoestructura. En ningún caso se realizó sobrecorrección del defecto en ningún caso. La evolución con un seguimiento máximo de 7 años y mínimo de 1 año no mostró disminución del volumen obtenido en el acto quirúrgico en la gran mayoría de los casos. Debido a los resultados obtenidos creemos que el injerto de grasa autólogo es el método de elección para restaurar volúmenes con fines estéticos o reconstructivos.Volume loss in several facial and body areas was treated by means of autologous fatty tissue grafts with lipostructure technique. There were no cases of overcorrection. The patients’ course, with a maximum follow-up of 7 years and a minimum of 1 year did not evidence any loss of the surgically restored tissue volume in the majority of cases. The above results suggest that autologous fat grafts are the method of choice to restore volume for both cosmetic and reconstructive purposes.

J. Planas

2006-03-01

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Supervivencia a largo plazo de los injertos grasos / Long-term survival with fat grafting  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish Presentamos varios casos de pérdida de volumen de diferentes etiologías y en distintas regiones corporales y faciales tratadas mediante injertos de tejido graso autólogo según la técnica de lipoestructura. En ningún caso se realizó sobrecorrección del defecto en ningún caso. La evolución con un segu [...] imiento máximo de 7 años y mínimo de 1 año no mostró disminución del volumen obtenido en el acto quirúrgico en la gran mayoría de los casos. Debido a los resultados obtenidos creemos que el injerto de grasa autólogo es el método de elección para restaurar volúmenes con fines estéticos o reconstructivos. Abstract in english Volume loss in several facial and body areas was treated by means of autologous fatty tissue grafts with lipostructure technique. There were no cases of overcorrection. The patients’ course, with a maximum follow-up of 7 years and a minimum of 1 year did not evidence any loss of the surgically resto [...] red tissue volume in the majority of cases. The above results suggest that autologous fat grafts are the method of choice to restore volume for both cosmetic and reconstructive purposes.

J., Planas; V., Cervelli; A., Pontón; G., Planas.

2006-03-01

47

Fats  

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... Text Size: A A A Listen En Español Fats Unhealthy fats Healthy fats No doubt about it, ... your heart health with that single change! Unhealthy Fats Saturated Fat Why should you eat less saturated ...

48

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49

Effects of Expanded Human Adipose Tissue-Derived Mesenchymal Stem Cells on the Viability of Cryopreserved Fat Grafts in the Nude Mouse  

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Full Text Available Adipose-derived mesenchymal stem cells (AdMSCs augment the ability to contribute to microvascular remodeling in vivo and to modulate vascular stability in fresh fat grafts. Although cryopreserved adipose tissue is frequently used for soft tissue augmentation, the viability of the fat graft is poor. The effects of culture-expanded human adipose tissue-derived mesenchymal stem cells (hAdMSCs on the survival and quality of the cryopreserved fat graft were determined. hAdMSCs from the same donor were mixed with fat tissues cryopreserved at -70°C for 8 weeks and injected subcutaneously into 6-week-old BALB/c-nu nude mice. Graft volume and weight were measured, and histology was evaluated 4 and 15 weeks post-transplantation. The hAdMSC-treated group showed significantly enhanced graft volume and weight. The histological evaluation demonstrated significantly better fat cell integrity compared with the vehicle-treated control 4 weeks post-transplantation. No significant difference in graft weight, volume, or histological parameters was found among the groups 15 weeks post-transplantation. The hAdMSCs enhanced the survival and quality of transplanted cryopreserved fat tissues. Cultured and expanded hAdMSCs have reconstructive capacity in cryopreserved fat grafting by increasing the number of stem cells.

Myung-Soon Ko, Ji-Youl Jung, Il-Seob Shin, Eun-Wha Choi, Jae-Hoon Kim, Sung Keun Kang, Jeong Chan Ra

2011-01-01

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51

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Full Text Available ... you than saturated fat and for a heart-healthy diet, you want to eat as little trans fat ... list them. Polyunsaturated Fat Polyunsaturated fats are also "healthy" fats. The Association recommends that you include these in your diet as well as monounsaturated fats. Like the other ...

52

Closure of oroantral communication using buccal fat pad graft - case report  

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Full Text Available Introduction: There are many causes of fistulas that involve the nasal and antral cavities or both. They may result from pathological entities or secondary to removal of tumors or maxillary cysts. However, the extraction of a maxillary molar or premolar is the most common cause of oroantral fistula. This is explained by the close relationship between the apex of these teeth and the thinness of the antral floor. When the primary fistula repair fails to heal spontaneously during the first three weeks after surgery, a secondary repair may be indicated. During treatment process of the fistulas, there are procedures to make a direct close or the use of a sliding mucosal flap, all techniques own an equal and high degree of failure. Objective: To show a case report of oroantral fistula and its closure. Case Report: A 6-month-Surgical treatment of oroantral fistula, after a tooth removal, using the buccal fat pad method as a pedicled graft associated with a sliding mucosal flap. Conclusion: The mentioned treatment is simple, complete and allows an extensive applicability in most of cases.

Keim, Frederico Santos

2008-09-01

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Miringoplastia com a utilização de um novo material biossintético Myringoplasty using a new biomaterial allograft  

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Full Text Available A miringoplastia é uma cirurgia com a finalidade de controlar a infecção no ouvido médio, reconstruir o mecanismo de transmissão sonora para a janela oval e proteger a janela redonda. São descritos diversos materiais para reconstruir a membrana timpânica, destacando-se a fáscia do músculo temporal, pericôndrio do tragus, cartilagem, dura-máter, tecido placentário, entre outros. OBJETIVO: Este trabalho tem objetivo de demonstrar o efeito de um novo biomaterial, a membrana de látex natural com polilisina, desenvolvida no laboratório de Neuroquímica do Departamento de Bioquímica da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo - USP. FORMA DE ESTUDO: Coorte Longitudinal. MATERIAL E MÉTODO: O biomaterial utilizado é estimulante da neovascularização e crescimento tecidual organizado em diferentes órgãos e tecidos, sendo um material inócuo e não rejeitado pelo organismo. Foi usada a biomembrana de látex com polilisina como um implante transitório para o fechamento da perfuração da membrana timpânica. A membrana foi colocada na face externa dos bordos da membrana timpânica e a fáscia temporal na face interna da mesma. Foram estudadas 238 orelhas com perfuração de membrana timpânica por seqüela de otite média crônica, submetidas a miringoplastia com enxerto de fáscia de músculo temporal e a membrana de látex natural, com idades de 7 a 76 anos. Apresentavam uma ou mais miringoplastias anteriores sem sucesso 41 dos casos. RESULTADO: Como ressaltamos preliminarmente, verificamos pega do enxerto em 90,5% das orelhas (181, sendo fechamento de perfuração amplas, 96; médias, 73 e 12 pequenas. Verificamos intensa vascularização em 100% dos enxertos, o que não é habitual quando não se usa a membrana de látex natural. CONCLUSÃO: Conclue-se que o biomaterial usado merece nossa atenção quanto ao seu uso como implante transitório em miringoplastias, melhorando o processo de revascularização da membrana timpânica remanescente.Myringosplaty is a surgery that is performed to control infections in middle ear, to reconstruct the sound conducting mechanism for the oval window and protection of the round window. Some materials are used to reconstruct the tympanic membrane like autologous temporalis fascia, cartilage-perichondium graft taken from the tragus, cartilage only, dura mater human placental graft. It is important the vascular support to the graft with well-vascularized flap in wide perforations. AIM: The main goal of this work is shown the use of a new biomaterial, the natural latex membrane with polylysin. STUDY DESIGN: Longitudinal Cohort. MATERIAL AND METHOD: This material was developed from Department of Biochemistry from Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo. The natural latex membrane is used stimulating neovessels and organized tecidual growing in different parts and tissues of the human body. This material promotes any allergic reaction and is innocuous to the human tissue. The 238 ears with tympanic membrane perforation resulted from chronic middle ear infection and thek was going through myringoplasty with autologous temporalis fascia and natural latex membrane. The ages were 7 to 76 years. RESULTS: The first results show 181 (90,5% healing tympanic membrane perforation, 96 healing of wide perforation 73 medium perforation and 12 small one. Neovessels could be seen in all grafts and remaining tympanic membrane. This is not a habitual funding when the natural latex membrane is not used. CONCLUSION: According to these results we can conclude that the natural latex membrane can be used as a temporary implant in myringoplasty, improving the well vascularized of remaining tympanic membrane.

José Antonio Apparecido de Oliveira

2003-10-01

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Miringoplastia com a utilização de um novo material biossintético / Myringoplasty using a new biomaterial allograft  

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Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese A miringoplastia é uma cirurgia com a finalidade de controlar a infecção no ouvido médio, reconstruir o mecanismo de transmissão sonora para a janela oval e proteger a janela redonda. São descritos diversos materiais para reconstruir a membrana timpânica, destacando-se a fáscia do músculo temporal, [...] pericôndrio do tragus, cartilagem, dura-máter, tecido placentário, entre outros. OBJETIVO: Este trabalho tem objetivo de demonstrar o efeito de um novo biomaterial, a membrana de látex natural com polilisina, desenvolvida no laboratório de Neuroquímica do Departamento de Bioquímica da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo - USP. FORMA DE ESTUDO: Coorte Longitudinal. MATERIAL E MÉTODO: O biomaterial utilizado é estimulante da neovascularização e crescimento tecidual organizado em diferentes órgãos e tecidos, sendo um material inócuo e não rejeitado pelo organismo. Foi usada a biomembrana de látex com polilisina como um implante transitório para o fechamento da perfuração da membrana timpânica. A membrana foi colocada na face externa dos bordos da membrana timpânica e a fáscia temporal na face interna da mesma. Foram estudadas 238 orelhas com perfuração de membrana timpânica por seqüela de otite média crônica, submetidas a miringoplastia com enxerto de fáscia de músculo temporal e a membrana de látex natural, com idades de 7 a 76 anos. Apresentavam uma ou mais miringoplastias anteriores sem sucesso 41 dos casos. RESULTADO: Como ressaltamos preliminarmente, verificamos pega do enxerto em 90,5% das orelhas (181), sendo fechamento de perfuração amplas, 96; médias, 73 e 12 pequenas. Verificamos intensa vascularização em 100% dos enxertos, o que não é habitual quando não se usa a membrana de látex natural. CONCLUSÃO: Conclue-se que o biomaterial usado merece nossa atenção quanto ao seu uso como implante transitório em miringoplastias, melhorando o processo de revascularização da membrana timpânica remanescente. Abstract in english Myringosplaty is a surgery that is performed to control infections in middle ear, to reconstruct the sound conducting mechanism for the oval window and protection of the round window. Some materials are used to reconstruct the tympanic membrane like autologous temporalis fascia, cartilage-perichondi [...] um graft taken from the tragus, cartilage only, dura mater human placental graft. It is important the vascular support to the graft with well-vascularized flap in wide perforations. AIM: The main goal of this work is shown the use of a new biomaterial, the natural latex membrane with polylysin. STUDY DESIGN: Longitudinal Cohort. MATERIAL AND METHOD: This material was developed from Department of Biochemistry from Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo. The natural latex membrane is used stimulating neovessels and organized tecidual growing in different parts and tissues of the human body. This material promotes any allergic reaction and is innocuous to the human tissue. The 238 ears with tympanic membrane perforation resulted from chronic middle ear infection and thek was going through myringoplasty with autologous temporalis fascia and natural latex membrane. The ages were 7 to 76 years. RESULTS: The first results show 181 (90,5%) healing tympanic membrane perforation, 96 healing of wide perforation 73 medium perforation and 12 small one. Neovessels could be seen in all grafts and remaining tympanic membrane. This is not a habitual funding when the natural latex membrane is not used. CONCLUSION: According to these results we can conclude that the natural latex membrane can be used as a temporary implant in myringoplasty, improving the well vascularized of remaining tympanic membrane.

José Antonio Apparecido de, Oliveira; Miguel Angelo, Hyppolito; Joaquim, Coutinho Netto; Fátima, Mrué.

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Full Text Available ... eat less saturated fat? Because saturated fat raises blood cholesterol levels. High blood cholesterol is a risk factor for ... Trans Fat Like saturated fat, trans fat increases blood cholesterol levels. It is actually worse for you than saturated ...

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Full Text Available ... healthy fats in their place. Instead of 1 cheese stick for an afternoon snack, have 12 almonds. ... High-fat dairy products such as full-fat cheese, cream, ice cream, whole milk, 2% milk and ...

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Full Text Available ... dairy products such as full-fat cheese, cream, ice cream, whole milk, 2% milk and sour cream. ... fat dairy products (whole or 2% milk, cream, ice cream, full-fat cheese) Egg yolks Liver and ...

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Full Text Available ... In Memory In Honor Become a Member En Español Type 1 Type 2 About Us Online Community ... Page Text Size: A A A Listen En Español Fats Unhealthy fats Healthy fats No doubt about ...

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Full Text Available ... will have improved your heart health with that single change! Unhealthy Fats Saturated Fat Why should you ... is about 20 grams of saturated fat per day. That is not much when you consider just ...

 
 
 
 
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Full Text Available ... Monthly In Memory In Honor Become a Member En Español Type 1 Type 2 About Us Online ... Print Page Text Size: A A A Listen En Español Fats Unhealthy fats Healthy fats No doubt ...

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Full Text Available ... carbohydrate gets all of the attention in diabetes management. More important than total fat is the type ... have improved your heart health with that single change! Unhealthy Fats Saturated Fat Why should you eat ...

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Full Text Available ... the attention in diabetes management. More important than total fat is the type of fat you eat. ... listed on the Nutrition Facts food label under total fat. As a general rule, compare foods with ...

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Injertos de tejido adiposo en cirugía estética mamaria / Fat grafts in aesthetic breast surgery  

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Full Text Available SciELO Spain | Language: Spanish Abstract in spanish El injerto de tejido adiposo se ha convertido en una de las principales herramientas con la que contamos en Cirugía Plástica y, como no podía ser de otra forma, la mama es el principal órgano diana de nuestra actuación. Desde que introdujimos la técnica en nuestra práctica privada en el año 2009 hem [...] os ido incrementando las indicaciones de su uso. Las tres principales son el aumento mamario, la corrección de defectos y asimetrías y más recientemente el aumento con combinación de ambas técnicas. El aumento mamario con tejido adiposo está indicado en pacientes que quieran incrementar el volumen sin usar implantes. Hay que explicar muy bien a la paciente lo que podemos conseguir en cuanto a volumen y proyección de la mama, además de los problemas potenciales de aparición en las mamografías de quistes y microcalcificaciones. El tejido adiposo, en cambio, es un gran complemento de los implantes mamarios, ya que permite corregir deformidades y asimetrías que con los implantes son más difíciles de resolver. El aumento de mamas combinando ambas técnicas es la consecuencia final y evidente de esta evolución terapéutica, ya que aúna las ventajas de ambas: la firmeza y volumen estables que proporcionan los implantes y la plasticidad que aporta el tejido adiposo para lograr una mayor simetría. Abstract in english Fat grafting has become one of the main tools in Plastic Surgery and as it could only be, the breast is the main target organ of our performance. Since we introduced the technique in our private practice in 2009 we have been increasing its use. The top three indications are: breast augmentation, cor [...] rection of defects and asymmetries and more recently breast augmentation combining both techniques. Breast enhancement with fat is indicated for patients who want to increase the volume without using implants. It must be explained very well to the patient what we can achieve in terms of volume and projection of the breast, along with the potential problems of cysts and microcalcifications in mammograms. Adipose tissue is a great complement to the implants, and we can correct deformities and asymmetries that with implants are much more difficult to solve. Breast augmentation combining both techniques is the final result of the therapeutic evolution as we combine the advantages of both: the firmness and stable volume supported by the implants and the plasticity of the adipose tissue to achieve greater symmetry.

J., Benito-Ruiz.

2013-12-01

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Meningitis due to Enterobacter aerogenes subsequent to resection of an acoustic neuroma and abdominal fat graft to the mastoid  

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Full Text Available Meningitis is an uncommon complication of neurosurgical procedures, with an incidence of 1.1% to 2.5%. Although unusual, the frequency of nosocomial Gram-negative meningitis appears to be increasing. Gram-negative meningitis has been documented following disruption of the dura-arachnoid barrier secondary to trauma or surgery. The association of Gram-negative bacillary meningitis with neurosurgical procedures was first reported in the 1940's. Wolff et al. described the association between Enterobacter species and post-neurosurgical infection. More recently, risk factors for nosocomial Enterobacter meningitis have been characterized by Parodi et al. Adipose graft, as an independent risk factor has not yet been reported. A patient with acoustic neuroma resection, who developed bacterial meningitis from an abdominal fat pad graft to a mastoidectomy bed is described. A brief overview was made of post-neurosurgical Gram-negative meningitis.

Fida A. Khan

2004-10-01

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Meningitis due to Enterobacter aerogenes subsequent to resection of an acoustic neuroma and abdominal fat graft to the mastoid  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english Meningitis is an uncommon complication of neurosurgical procedures, with an incidence of 1.1% to 2.5%. Although unusual, the frequency of nosocomial Gram-negative meningitis appears to be increasing. Gram-negative meningitis has been documented following disruption of the dura-arachnoid barrier seco [...] ndary to trauma or surgery. The association of Gram-negative bacillary meningitis with neurosurgical procedures was first reported in the 1940's. Wolff et al. described the association between Enterobacter species and post-neurosurgical infection. More recently, risk factors for nosocomial Enterobacter meningitis have been characterized by Parodi et al. Adipose graft, as an independent risk factor has not yet been reported. A patient with acoustic neuroma resection, who developed bacterial meningitis from an abdominal fat pad graft to a mastoidectomy bed is described. A brief overview was made of post-neurosurgical Gram-negative meningitis.

Fida A., Khan.

67

Fat embolism in liposuction and intramuscular grafts in rabbits Embolia gordurosa na lipoaspiração e enxertia intramuscular em coelhos  

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Full Text Available PURPOSE: To evaluate the effects of fat embolism in organs such as lung and liver. METHODS: Twenty rabbits underwent autologous intramuscular fat grafting in the right thigh after liposuction. The groups were determined according to the postoperative day that occurred in euthanasia: 60, 90 and 120 day. Then, lung and liver were excised and sent to the histopathology laboratory for analysis in search of late injury secondary to a prior event of fat embolism in the tissues. RESULTS: The results showed a change in the macroscopic sample with discoloration of the liver tissue heterogeneously. There were no changes consistent with embolic effect under the microscope. CONCLUSION: The option of performing a technique of fat grafting with a less traumatic surgical procedure can be considered protective against embolic events, with no impact to late embolic events on the tissues.OBJETIVO: Avaliar a repercussão da embolia gordurosa em ?rgãos como pulmão e fígado. MÉTODOS: Vinte coelhos foram submetidos à enxertia autóloga intramuscular de gordura em coxa direita após lipoaspiração. Os grupos foram determinados conforme os dias pós-operatórios (DPO em que ocorreu a eutanásia: 60 DPO, 90DPO, 120 DPO. Em seguida, o pulmão e o fígado foram ressecados e encaminhados ao laboratório de histopatologia para análise em busca de lesão tardia secundária a evento de embolia gordurosa prévia nos tecidos. RESULTADOS: Foi evidenciada uma alteração na amostra a analise macroscópica com alteração da coloração do tecido hepático de forma heterogênea. Não houve alterações compatíveis com repercussão de processo embólico à microscopia. CONCLUSÃO: A opção pela realização de uma técnica de lipoenxertia menos traumática e com pequeno tempo cirúrgico pode ser considerada protetora para eventos embólicos, não havendo repercussão embólica a tardiamente.

Victor Araujo Felzemburgh

2012-05-01

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Fat embolism in liposuction and intramuscular grafts in rabbits / Embolia gordurosa na lipoaspiração e enxertia intramuscular em coelhos  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Avaliar a repercussão da embolia gordurosa em órgãos como pulmão e fígado. MÉTODOS: Vinte coelhos foram submetidos à enxertia autóloga intramuscular de gordura em coxa direita após lipoaspiração. Os grupos foram determinados conforme os dias pós-operatórios (DPO) em que ocorreu a eutanásia [...] : 60 DPO, 90DPO, 120 DPO. Em seguida, o pulmão e o fígado foram ressecados e encaminhados ao laboratório de histopatologia para análise em busca de lesão tardia secundária a evento de embolia gordurosa prévia nos tecidos. RESULTADOS: Foi evidenciada uma alteração na amostra a analise macroscópica com alteração da coloração do tecido hepático de forma heterogênea. Não houve alterações compatíveis com repercussão de processo embólico à microscopia. CONCLUSÃO: A opção pela realização de uma técnica de lipoenxertia menos traumática e com pequeno tempo cirúrgico pode ser considerada protetora para eventos embólicos, não havendo repercussão embólica a tardiamente. Abstract in english PURPOSE: To evaluate the effects of fat embolism in organs such as lung and liver. METHODS: Twenty rabbits underwent autologous intramuscular fat grafting in the right thigh after liposuction. The groups were determined according to the postoperative day that occurred in euthanasia: 60, 90 and 120 d [...] ay. Then, lung and liver were excised and sent to the histopathology laboratory for analysis in search of late injury secondary to a prior event of fat embolism in the tissues. RESULTS: The results showed a change in the macroscopic sample with discoloration of the liver tissue heterogeneously. There were no changes consistent with embolic effect under the microscope. CONCLUSION: The option of performing a technique of fat grafting with a less traumatic surgical procedure can be considered protective against embolic events, with no impact to late embolic events on the tissues.

Victor Araujo, Felzemburgh; Rafaela Cavalcante das Neves, Barbosa; Victor Luiz Correia, Nunes; José Humberto Oliveira, Campos.

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Fat embolism in liposuction and intramuscular grafts in rabbits / Embolia gordurosa na lipoaspiração e enxertia intramuscular em coelhos  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Avaliar a repercussão da embolia gordurosa em órgãos como pulmão e fígado. MÉTODOS: Vinte coelhos foram submetidos à enxertia autóloga intramuscular de gordura em coxa direita após lipoaspiração. Os grupos foram determinados conforme os dias pós-operatórios (DPO) em que ocorreu a eutanásia [...] : 60 DPO, 90DPO, 120 DPO. Em seguida, o pulmão e o fígado foram ressecados e encaminhados ao laboratório de histopatologia para análise em busca de lesão tardia secundária a evento de embolia gordurosa prévia nos tecidos. RESULTADOS: Foi evidenciada uma alteração na amostra a analise macroscópica com alteração da coloração do tecido hepático de forma heterogênea. Não houve alterações compatíveis com repercussão de processo embólico à microscopia. CONCLUSÃO: A opção pela realização de uma técnica de lipoenxertia menos traumática e com pequeno tempo cirúrgico pode ser considerada protetora para eventos embólicos, não havendo repercussão embólica a tardiamente. Abstract in english PURPOSE: To evaluate the effects of fat embolism in organs such as lung and liver. METHODS: Twenty rabbits underwent autologous intramuscular fat grafting in the right thigh after liposuction. The groups were determined according to the postoperative day that occurred in euthanasia: 60, 90 and 120 d [...] ay. Then, lung and liver were excised and sent to the histopathology laboratory for analysis in search of late injury secondary to a prior event of fat embolism in the tissues. RESULTS: The results showed a change in the macroscopic sample with discoloration of the liver tissue heterogeneously. There were no changes consistent with embolic effect under the microscope. CONCLUSION: The option of performing a technique of fat grafting with a less traumatic surgical procedure can be considered protective against embolic events, with no impact to late embolic events on the tissues.

Victor Araujo, Felzemburgh; Rafaela Cavalcante das Neves, Barbosa; Victor Luiz Correia, Nunes; José Humberto Oliveira, Campos.

2012-05-01

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Full Text Available ... For most people, eating this is about 20 grams of saturated fat per day. That is not ... just one ounce of cheese can have 8 grams of saturated fat. Many adults, especially women or ...

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Full Text Available ... carbohydrate gets all of the attention in diabetes management. More important than total fat is the type ... However, if there is not at least 0.5 grams or more of trans fat in a ...

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Full Text Available ... calories the same by cutting back on the sources of saturated and trans fats, while substituting the ... oil is listed first in the ingredient list. Sources of trans fat include: Processed foods like snacks ( ...

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Full Text Available ... that contain it. Trans fats are produced when liquid oil is made into a solid fat. This ... do not contain hydrogenated oil or where a liquid oil is listed first in the ingredient list. ...

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Full Text Available ... replace the sources of saturated fat in your diet with polyunsaturated fats. Sources of ... arteries. Some types of fish are high in omega-3 fatty acids. The Association recommends ...

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Full Text Available ... with diabetes are at high risk for heart disease and limiting your saturated fat can help lower your risk of having a heart attack or stroke. Foods containing saturated fat include: Lard Fatback and salt ...

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Full Text Available ... LDL) cholesterol. Sources of monounsaturated fat include: Avocado Canola oil Nuts like almonds, cashews, pecans, and peanuts Olive ... more monounsaturated fats, try to substitute olive or canola oil instead of butter, margarine or shortening when cooking. ...

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Full Text Available ... and "unhealthy fats." To lower you risk of heart disease, try to eat less saturated and trans fat — ... High blood cholesterol is a risk factor for heart disease. People with diabetes are at high risk for ...

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Full Text Available ... Can I Eat? Making Healthy Food Choices Diabetes Superfoods Non-starchy Vegetables Grains and Starchy Vegetables Fats ... Can I Eat Making Healthy Food Choices Diabetes Superfoods Fats Alcohol Non-starchy Vegetables Grains and Starchy ...

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Full Text Available ... help lower your risk of having a heart attack or stroke. Foods containing saturated fat include: Lard Fatback and salt pork High-fat meats like regular ground beef, bologna, hot dogs, sausage, bacon and spareribs High-fat dairy products ...

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Supplementation of fat grafts with adipose-derived regenerative cells in reconstructive surgery [Stammzellangereicherte Fetttransplantation in der rekonstruktiven Chirurgie  

Directory of Open Access Journals (Sweden)

Full Text Available [english] Introduction: The fraction of regenerative cells in adipose tissue has been described to be even higher than in bone marrow. Adipose tissue itself is excessively available in most patients. Given that adipose tissue is abundant in majority of patients adipose derrived stem cells (ASCs have come under scrutiny for regenerative procedures in reconstructive surgery.Material and methods: ASCs were extracted by the Celution system for enrichment of fat grafts that were administered in patients with decreased wound healing, soft tissue or scar defects.Results: All patients were satisfied after reconstruction with ASCs augmented fat grafts and no side effects were observed. Discussion: The Celution system provides fast recovery of ASCs which can be immediately utilized for appropriate application. Since a high number of stem cells are harvested from fat tissue no expansion of cells is needed as described for bone marrow derived stem cells. Enrichment of fat graft with ASCs is of great interest due to their reported angiogenetic effect. The reported cases demonstrate the potential of ASCs in the field of regenerative medicine and encourage further application in reconstructive surgery.[german] Einleitung: Es konnte gezeigt werden, dass der Anteil regenerativer Zellen im Fettgewebe höher als im Knochenmark ist. Fettgewebe hingegen ist bei den meisten Patienten exzessiv vorhanden. Das legt den Einsatz von ASCs (adipose derived stem cells bei regenerativen Anwendungen in der rekonstruktiven Chirurgie nahe.Material und Methoden: Mit dem Celution System von Cytori Therapeutics Inc. prozessierte, ASC angereicherte Fetttransplantate werden an vier Patienten mit Weichteildefiziten und störenden Narben sowie Wundheilungsstörungen angewendet.Ergebnisse: Insbesondere bei Patienten mit Weichteildefiziten und Narben konnte eine suffiziente Volumenaugmentation und ansprechende Verbesserung der Narben erzielt werden. Es wurden keine Nebenwirkungen festgestellt.Diskussion: Der angiogenetische Effekt ist ein interessanter Faktor bei der autologen Fetttransplantation. Ein großer Vorteil von ASCs, die mit dem Celution System prozessiert werden, ist deren sofortige Verfügbarkeit. Es entfällt somit eine lang dauernde Prozessierung im Labor. Die vorgestellten klinischen Beispiele verdeutlichen das Potential von ASCs in der regenerativen Medizin und eröffnen neue Möglichkeiten deren Anwendung in der rekonstruktiven Chirurgie.

Herold, C.

2012-09-01

88

COMPARATIVE STUDY OF MANAGEMENT WITH MYRINGOPLASTY AND CHEMICAL CAUTERISATION IN TUBO-TYMPANIC TYPE OF CHRONIC SUPPURATIVE OTITIS MEDIA  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction CSOM is highly prevalent chronic ear disease. In developing countries like India, where tertiary medical facility is not available to all people, treatment should be cost effective and easily feasible at even primary health centre. With this background a study was performed for closure of small to moderate central perforation with chemical cauterisation and to see whether it is equally effective as that of Myringoplasty or not.Study design: prospective clinical study.Methodology: To compare results of chemical cauterisation (TCA with myringoplasty on non healing small and medium sized central tympanic membrane perforation of pars tensa, 100 patients with dry tympanic membrane perforations. Result:1 Success rate with myringoplasty and chemical cauterisation were 76% and 72% respectively.2 The improvement of hearing at 3rd month of follow-up after successful procedure with myringoplasty and chemical cauterisation in term of air bone gap less than 10 db were 68.4% and 88.88% respectivelyConclusion:1 For closure of small central perforation chemical cauterisation is equally effective as myringoplasty.2 For closure of moderate central perforation, myringoplasty is superior to chemical cauterisation.3 Hearing improvement was observed better for chemical cauterisation as compared to Myringoplasty.

Kiran J Shinde

2013-12-01

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Comparative analysis of use of porous orbital implant with mucus membrane graft and dermis fat graft as a primary procedure in reconstruction of severely contracted socket  

Science.gov (United States)

Purpose: The purpose of our study is to present a surgical technique of primary porous orbital ball implantation with overlying mucus membrane graft (MMG) for reconstruction of severely contracted socket and to evaluate prosthesis retention and motility in comparison to dermis fat graft (DFG). Study Design: Prospective comparative study. Materials and Methods: A total of 24 patients of severe socket contracture (Grade 2-4 Krishna's classification) were subdivided into two groups, 12 patients in each group. In Group I, DFG have been used for reconstruction. In Group II, porous polyethylene implant with MMG has been used as a primary procedure for socket reconstruction. In Group I DFG was carried out in usual procedure. In case of Group II, vascularized scar tissues were separated 360° and were fashioned into four strips. A scleral capped porous polyethylene implant was placed in the intraconal space and four strips of scar tissue were secured to the scleral cap and extended part overlapped the implant to make a twofold barrier between the implant and MMG. Patients were followed-up as per prefixed proforma. Prosthesis motility and retention between the two groups were measured. Results: In Group I, four patients had recurrence of contracture with fall out of prosthesis. In Group II stable reconstruction was achieved in all the patients. In terms of prosthesis motility, maximum in Group I was 39.2% and Group II, was 59.3%. The difference in prosthesis retention (P = 0.001) and motility (P = 0.004) between the two groups was significant. Conclusion: Primary socket reconstruction with porous orbital implant and MMG for severe socket contracture is an effective method in terms of prosthesis motility and prosthesis retention. PMID:24618485

Bhattacharjee, Kasturi; Bhattacharjee, Harsha; Kuri, Ganesh; Das, Jayanta Kr; Dey, Debleena

2014-01-01

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Análise da lipoenxertia estruturada na redefinição do contorno facial / Analysis of structured fat grafting for redefining facial contours  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese INTRODUÇÃO: A enxertia de gordura como preenchimento no rejuvenescimento e melhoria do contorno facial vem sendo usada por alguns autores e demonstra um potencial excelente como método de escolha para essa finalidade, uma vez que tem como premissa o princípio básico de corrigir as deformidades com o [...] tecido mais semelhante possível. O objetivo deste trabalho foi avaliar clinicamente a eficiência da enxertia de gordura estruturada na redefinição do contorno facial. MÉTODO: Foi realizada análise retrospectiva de 39 pacientes submetidos a lipoenxertia estruturada para a redefinição do contorno facial, entre 2002 e 2012. A seleção de pacientes incluiu correção de deformidades, assimetrias, harmonização do contorno e aumento da projeção óssea, mas excluiu o rejuvenescimento per se. A avaliação do resultado clínico foi realizada pelo paciente e pelo cirurgião, com auxílio de documentação fotográfica pré e pós-operatória. O resultado clínico foi classificado pelo paciente e cirurgião, empregando escala que variava de 1 a 3: (1) o objetivo não foi alcançado de forma alguma; (2) o objetivo foi alcançado parcialmente; ou (3) o objetivo foi alcançado totalmente. Foi realizado, também, levantamento de prontuários para obtenção dos seguintes dados: idade, alteração ponderal, volume enxertado por área, número de sessões de enxertia realizadas, história de tabagismo e complicações. RESULTADOS: As médias das avaliações do cirurgião e paciente foram, respectivamente, 2,6 ± 0,6 e 2,7 ± 0,5, havendo correlação estatisticamente significante (P Abstract in english INTRODUCTION: Fat grafting as a filling method for the rejuvenation and enhancement of facial contours was demonstrated by some authors to be an excellent alternative method for redefining facial contours, based on the premise that the donor tissue used in the correction of the deformities has simil [...] ar characteristics as the recipient tissue. The objective of the present study was to clinically evaluate the efficiency of structured fat grafting when redefining facial contours. METHODS: A retrospective evaluation was performed in 39 patients who underwent structured fat grafting to redefine their facial contours between 2002 and 2012. The patients selected included those who underwent corrections of deformities, asymmetrical features, contour smoothing, and increased bone projection. Patients who underwent facial contour rejuvenation were excluded. The clinical outcome assessment was performed by the patient and surgeon, with the aid of preoperative and postoperative photographic documentation. The clinical outcome was rated by the patient and surgeon, using a scale ranging from 1 to 3, defined as follows: 1, the objective has not been achieved in any way; 2, the objective was partially achieved; or 3, the objective was fully achieved. In addition, a survey was conducted using the patients' medical charts to obtain the following data: age, weight change, volume grafted by area, number of grafting sessions performed, history of smoking, and complications. RESULTS: The mean surgeon and patient assessment scores were 2.6 ± 0.6 and 2.7 ± 0.5, respectively, with a statistically significant correlation (P

Marco Túlio Junqueira, Amarante.

94

Análise da lipoenxertia estruturada na redefinição do contorno facial / Analysis of structured fat grafting for redefining facial contours  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese INTRODUÇÃO: A enxertia de gordura como preenchimento no rejuvenescimento e melhoria do contorno facial vem sendo usada por alguns autores e demonstra um potencial excelente como método de escolha para essa finalidade, uma vez que tem como premissa o princípio básico de corrigir as deformidades com o [...] tecido mais semelhante possível. O objetivo deste trabalho foi avaliar clinicamente a eficiência da enxertia de gordura estruturada na redefinição do contorno facial. MÉTODO: Foi realizada análise retrospectiva de 39 pacientes submetidos a lipoenxertia estruturada para a redefinição do contorno facial, entre 2002 e 2012. A seleção de pacientes incluiu correção de deformidades, assimetrias, harmonização do contorno e aumento da projeção óssea, mas excluiu o rejuvenescimento per se. A avaliação do resultado clínico foi realizada pelo paciente e pelo cirurgião, com auxílio de documentação fotográfica pré e pós-operatória. O resultado clínico foi classificado pelo paciente e cirurgião, empregando escala que variava de 1 a 3: (1) o objetivo não foi alcançado de forma alguma; (2) o objetivo foi alcançado parcialmente; ou (3) o objetivo foi alcançado totalmente. Foi realizado, também, levantamento de prontuários para obtenção dos seguintes dados: idade, alteração ponderal, volume enxertado por área, número de sessões de enxertia realizadas, história de tabagismo e complicações. RESULTADOS: As médias das avaliações do cirurgião e paciente foram, respectivamente, 2,6 ± 0,6 e 2,7 ± 0,5, havendo correlação estatisticamente significante (P Abstract in english INTRODUCTION: Fat grafting as a filling method for the rejuvenation and enhancement of facial contours was demonstrated by some authors to be an excellent alternative method for redefining facial contours, based on the premise that the donor tissue used in the correction of the deformities has simil [...] ar characteristics as the recipient tissue. The objective of the present study was to clinically evaluate the efficiency of structured fat grafting when redefining facial contours. METHODS: A retrospective evaluation was performed in 39 patients who underwent structured fat grafting to redefine their facial contours between 2002 and 2012. The patients selected included those who underwent corrections of deformities, asymmetrical features, contour smoothing, and increased bone projection. Patients who underwent facial contour rejuvenation were excluded. The clinical outcome assessment was performed by the patient and surgeon, with the aid of preoperative and postoperative photographic documentation. The clinical outcome was rated by the patient and surgeon, using a scale ranging from 1 to 3, defined as follows: 1, the objective has not been achieved in any way; 2, the objective was partially achieved; or 3, the objective was fully achieved. In addition, a survey was conducted using the patients' medical charts to obtain the following data: age, weight change, volume grafted by area, number of grafting sessions performed, history of smoking, and complications. RESULTS: The mean surgeon and patient assessment scores were 2.6 ± 0.6 and 2.7 ± 0.5, respectively, with a statistically significant correlation (P

Marco Túlio Junqueira, Amarante.

2013-03-01

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Full Text Available ... Student Resources History of Diabetes Resources for School Projects How to Reference Our Site Diabetes Basics Myths ... carbohydrate gets all of the attention in diabetes management. More important than total fat is the type ...

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Full Text Available ... Type 2 Diabetes Know Your Rights Employment Discrimination Health Care Professionals Law Enforcement Driver's License For Lawyers Food & ... goal for you, talk with your dietitian or health care provider. Saturated fat grams are listed on the ...

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Full Text Available ... Healthy Food Choices Diabetes Superfoods Non-starchy Vegetables Grains and Starchy Vegetables Fats Alcohol What Can I ... or sunflower seeds on a salad, yogurt, or cereal is an easy way to eat more monounsaturated ...

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Full Text Available ... carbohydrate gets all of the attention in diabetes management. More important than total fat is the type ... you are trying to lose or maintain your weight, you want to eat small portions of these ...

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Full Text Available ... Diets Meal Planning for Vegetarian Diets Cook with Heart-Healthy Foods Holiday Meal Planning What Can I ... and "unhealthy fats." To lower you risk of heart disease, try to eat less saturated and trans ...

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Engineering articular cartilage-like grafts by self-assembly of infrapatellar fat pad-derived stem cells.  

Science.gov (United States)

Well documented limitations associated with primary chondrocytes for cartilage tissue engineering applications have led to increased interest in the use of multi-potent stem/progenitor cells. The objective of this study was to firstly investigate if infrapatellar fat pad-derived stem cells (FPSCs) could be used to engineer cartilage-like tissues through a self-assembly (SA) process, and secondly to compare the properties of such grafts to those engineered by agarose hydrogel encapsulation (AE). Self-assembled cartilaginous tissues were first engineered by geometrically confining FPSCs on tissue culture plastic, and then either continuously or transiently supplementing these constructs with transforming growth factor-b3 (TGF-b3). Transient supplementation with TGF-b3 (for the first 21 days of culture) enhanced the development of self-assembled grafts, with sGAG accumulation reaching levels of 8.4 ± 1.5% w/w after 6 weeks of culture. While overall levels of matrix synthesis were higher with AE compared to SA, when normalized to tissue wet weight, ECM accumulation was significantly greater in the lighter SA constructs. A potential drawback with the SA approach on tissue culture plastic was that it often led to the development of contracted,geometrically inconsistent tissues.We therefore next explored if SA on polyethylene terephthalate (PET) transwell membranes would lead to the development of more morphologically stable and homogenous tissues. At high seeding densities, SA on such transwell membranes led to the formation of geometrically uniform constructs that underwent minimal contraction during culture. In conclusion, the results of this study demonstrate the potential of SA using FPSCs for cartilage tissue engineering, with grafts attaining relatively high levels of sGAG content within clinically relevant timeframes. Such an approach is easily scalable and may lend itself to treating large, full thickness cartilage defects. PMID:25097913

Mesallati, Tariq; Buckley, Conor T; Kelly, Daniel J

2014-08-01

112

Lipoestructura y relleno del polo superior de la mama frente a implantes / Structural fat graft and lipofilling of mammary upper pole versus mammary implants  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish La lipoestructura mamaria ofrece nuevas alternativas de tratamiento en la cirugía estética de aumento mamario, cumpliendo en algunos casos las expectativas esperadas y en otros no. Analizamos este hecho en 4 tipos de aplicación de lipoestructura mamaria que hemos venido realizando en los últimos año [...] s, centrándonos en un aspecto importante de esta cirugía que es el relleno del polo superior de la mama. Los tipos de aplicación empleados son: aumento mamario simple mediante lipoestructura en comparación con implantes; pexia más lipoestructura frente a pexia más implantes mamarios; reconstrucción de mama tuberosa mediante lipoestructura o implantes y finalmente, relleno periprotésico mediante lipoestructura en mamas sometidas a cirugía de aumento mamario con implantes. En definitiva, podríamos resumir este trabajo en una frase diciendo que la lipoestructura mamaria, a nuestro juicio, no sirve si lo que prima es conseguir el relleno del polo superior de la mama, siendo en este caso de elección la colocación de implantes mamarios. No obstante, en alguno de los casos señalados no solo es una alternativa, sino que obtiene resultados superiores a los logrados sólamente con implantes. Abstract in english The mammary structural fat graft offers news treatment options in breast augmentation cosmetic surgery, but it sometimes meets expectations and sometimes doesn´t. We analyze 4 different types of lipostructure mammary applications that we have been using in the last years, focused in an important asp [...] ect of this surgery as it´s the filling of the upper mammary pole. These applications are: mammary augmentation by simple structural fat compared with the use of mammary implants; structural fat graft and mastopexy versus implants and mastopexy; tuberous breast reconstruction using structural fat graft or implants and finally, periprosthetic filling in breast augmentation with mammary implants using structural fat graft. In short, we could summarize this paper telling that in our opinion, structural fat graft doesn´t work if our intention is to fill the upper mammary pole. However, structural fat graft is not only an alternative; in some cases it exceeds the expected results using mammary implants.

J.M., Cervilla Lozano.

2012-09-01

113

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Full Text Available ... who might become pregnant; women who are pregnant; nursing mothers; and young children. Your fish and shellfish consumption should be limited to no more than 12 oz. per week. Get a more detailed explanation from the FDA . Patient Education Materials — Protect Your Heart: Choose Healthy Fats This ...

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Full Text Available ... polyunsaturated fats are: Corn oil Cottonseed oil Safflower oil Soybean oil Sunflower oil Walnuts Pumpkin or sunflower seeds Soft ( ... 3 fatty acids. Sources include: Tofu and other soybean products Walnuts Flaxseed and flaxseed oil Canola oil NOTE: The Food & Drug Administration and ...

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Full Text Available ... this section Food What Can I Eat Making Healthy Food Choices Diabetes Superfoods Fats Alcohol Non-starchy Vegetables Grains and Starchy Vegetables Protein Foods What Can I Drink? Dairy Fruits donate en -- Cherish their Memory - 2014-sept- ...

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Full Text Available ... foods. However, if there is not at least 0.5 grams or more of trans fat in a food, the label can claim 0 grams. If you want to avoid as much ... and help Stop Diabetes. Each survey earns a $0.50 donation for the Association. » « Connect With Us ...

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Full Text Available ... 24, 2014 Articles from Diabetes Forecast® magazine: wcie-nutrition, In this section Food What Can I Eat Making Healthy Food Choices Diabetes Superfoods Fats Alcohol Non-starchy Vegetables Grains and Starchy Vegetables Protein Foods What Can I Drink? Dairy Fruits donate ...

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Full Text Available ... Sources of monounsaturated fat include: Avocado Canola oil Nuts like almonds, cashews, pecans, and peanuts Olive oil and olives Peanut butter and peanut oil Sesame seeds The Association recommends ... when cooking. Sprinkling a few nuts or sunflower seeds on a salad, yogurt, or ...

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Full Text Available ... this section Food What Can I Eat Making Healthy Food Choices Diabetes Superfoods Fats Alcohol Non-starchy Vegetables Grains and Starchy Vegetables Protein Foods What Can I Drink? Dairy Fruits donate en -- Be TWICE as AWESOME! - 2014- ...

 
 
 
 
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Full Text Available ... Olive oil and olives Peanut butter and peanut oil Sesame seeds The Association recommends eating more monounsaturated fats than ... oil Cottonseed oil Safflower oil Soybean oil Sunflower oil Walnuts Pumpkin or sunflower seeds Soft (tub) margarine Mayonnaise Salad dressings Omega-3 ...

122

Preoperative color duplex echographical venous mapping before autologous fat graft for calf augmentation: a case report of superficial vein thrombosis and prevalence of intersaphenic anastomosis.  

Science.gov (United States)

Autologous fat grafting for calf augmentation is considered an easy and safe technique. Only few cases of potential complications have been described in literature; among them, vein thrombosis was never reported. We report a case of superficial vein thrombosis of the intersaphenic anastomosis after fat graft for calf symmetrization in club-foot syndrome. A color duplex echographical study showed that such intersaphenic anastomoses are present in all patients, but they have an ectatic diameter in 70% of patients with great saphenous vein insufficiency and in 50% of patients without insufficiency. The plastic surgeon should be aware of the presence and topography of such anatomical variations before performing the procedure. Moreover, a preoperative color duplex echographical venous mapping may help the surgeon in avoiding the trauma on vein variants and subsequent complications. PMID:23528632

Fraccalvieri, Marco; Contessa, Luigi; Salomone, Marco; Zingarelli, Enrico Maria; Bruschi, Stefano

2014-08-01

123

Síndrome da angústia respiratória do adulto por embolia gordurosa no período pós-operatório de lipoaspiração e lipoenxertia / Adult respiratory distress syndrome due to fat embolism in the postoperative period following liposuction and fat grafting  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese A embolia gordurosa é definida como a ocorrência de bloqueio mecânico da luz vascular por gotículas circulantes de gordura. Acomete principalmente o pulmão, podendo afetar também o sistema nervoso central, a retina e a pele. A síndrome da embolia gordurosa é uma disfunção desses órgãos causada pelos [...] êmbolos gordurosos. As causas mais comuns de embolia gordurosa e síndrome da embolia gordurosa são as fraturas de ossos longos, mas há relatos de sua ocorrência após procedimentos estéticos. O diagnóstico é clínico, e o tratamento ainda se restringe a medidas de suporte. Apresentamos o caso de uma paciente que evoluiu com síndrome da angústia respiratória do adulto por embolia gordurosa no período pós-operatório de lipoaspiração e lipoenxertia e respondeu bem às manobras de recrutamento alveolar e à ventilação mecânica protetora.Apresentamos também uma análise epidemiológica e fisiopatológica da síndrome da embolia gordurosa após procedimentos estéticos. Abstract in english Fat embolism is defined as mechanical blockage of the vascular lumen by circulating fat globules. Although it primarily affects the lungs, it can also affect the central nervous system, retina, and skin. Fat embolism syndrome is a dysfunction of these organs caused by fat emboli. The most common cau [...] ses of fat embolism and fat embolism syndrome are long bone fractures, although there are reports of its occurrence after cosmetic procedures. The diagnosis is made clinically, and treatment is still restricted to support measures. We report the case of a female patient who developed adult respiratory distress syndrome due to fat embolism in the postoperative period following liposuction and fat grafting. In this case, the patient responded well to alveolar recruitment maneuvers and protective mechanical ventilation. In addition, we present an epidemiological and pathophysiological analysis of fat embolism syndrome after cosmetic procedures.

André Nathan, Costa; Daniel Melo, Mendes; Carlos, Toufen; Gino, Arrunátegui; Pedro, Caruso; Carlos Roberto Ribeiro de, Carvalho.

2008-08-01

124

Peri-umbilical superficial fascial graft myringoplasty--a simple alternative.  

Science.gov (United States)

We present new material in the surgical repair of the perforated tympanic membrane. Forty-two patients with a unilateral tympanic membrane perforation and eight patients with bilateral perforations had their perforations closed with peri-umbilical superficial fascia via a transtympanic route. Of the 58 tympanic membranes repaired, 51 were successful while seven failed. The technique is cost-effective and quick, making bilateral repairs possible under the same anaesthetic. PMID:8877216

Ajulo, S O; Myatt, H M; Alusi, G

1993-10-01

125

Stromal vascular fraction (SVF) cells enhance long-term survival of autologous fat grafting through the facilitation of M2 macrophages.  

Science.gov (United States)

Optimum perfusion may be the key to the endurance, and hence survival, of autologous adipose tissue transportation. Stromal vascular fraction (SVF) cell therapy can greatly improve the survival of fat grafts by enhancing angiogenesis. However, SVF cells are poorly retained in later stages of SVF-assisted adipose tissue transplant. Therefore, it hardly defines the angiogenic effect through long-term transportation. Adipose tissue suffers from acute hypoxia in the early stage of transportation, leading to the recruitment of macrophages. M2 macrophages enhance angiogenesis in adipose transplantation by acting as an angiogenic signal source, promoting tip cell migration and assisting tip cell fusion. Furthermore, the angiogenic and anti-inflammatory micro-environment in the graft created by M2 macrophages may stimulate the transformation of infiltrating macrophages to M2 macrophages. These M2 macrophages may enhance the long-term retention of graft through angiogenesis. Based on these observations, we postulate that the long-term angiogenic effect of SVF cells may be achieved through the facilitation of the M2 macrophages. PMID:23526646

Dong, Ziqing; Fu, Rong; Liu, Linqi; Lu, Feng

2013-08-01

126

Infrapatellar Fat Pad-Derived Stem Cells Maintain Their Chondrogenic Capacity in Disease and Can be Used to Engineer Cartilaginous Grafts of Clinically Relevant Dimensions.  

Science.gov (United States)

A therapy for regenerating large cartilaginous lesions within the articular surface of osteoarthritic joints remains elusive. While tissue engineering strategies such as matrix-assisted autologous chondrocyte implantation can be used in the repair of focal cartilage defects, extending such approaches to the treatment of osteoarthritis will require a number of scientific and technical challenges to be overcome. These include the identification of an abundant source of chondroprogenitor cells that maintain their chondrogenic capacity in disease, as well as the development of novel approaches to engineer scalable cartilaginous grafts that could be used to resurface large areas of damaged joints. In this study, it is first demonstrated that infrapatellar fat pad-derived stem cells (FPSCs) isolated from osteoarthritic (OA) donors possess a comparable chondrogenic capacity to FPSCs isolated from patients undergoing ligament reconstruction. In a further validation of their functionality, we also demonstrate that FPSCs from OA donors respond to the application of physiological levels of cyclic hydrostatic pressure by increasing aggrecan gene expression and the production of sulfated glycosaminoglycans. We next explored whether cartilaginous grafts could be engineered with diseased human FPSCs using a self-assembly or scaffold-free approach. After examining a range of culture conditions, it was found that continuous supplementation with both transforming growth factor-?3 (TGF-?3) and bone morphogenic protein-6 (BMP-6) promoted the development of tissues rich in proteoglycans and type II collagen. The final phase of the study sought to scale-up this approach to engineer cartilaginous grafts of clinically relevant dimensions (?2?cm in diameter) by assembling FPSCs onto electrospun PLLA fiber membranes. Over 6 weeks in culture, it was possible to generate robust, flexible cartilage-like grafts of scale, opening up the possibility that tissues engineered using FPSCs derived from OA patients could potentially be used to resurface large areas of joint surfaces damaged by trauma or disease. PMID:24785365

Liu, Yurong; Buckley, Conor Timothy; Almeida, Henrique V; Mulhall, Kevin J; Kelly, Daniel John

2014-11-01

127

Utilidad del los injertos de tejido adiposo en la reconstrucción estética del miembro inferior / Use of autologous fat grafting in aesthetic lower extremity reconstruction  

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Full Text Available SciELO Spain | Language: Spanish Abstract in spanish La reconstrucción del miembro inferior constituye, probablemente, una de las disciplinas más complejas y de más difícil ejecución en el ámbito de la Cirugía Plástica Estética, independientemente de la etiología inicial del problema (postraumática, oncológica o congénita) y, normalmente, tras varios [...] tratamientos quirúrgicos, el paciente puede solicitar la mejora estética de las secuelas residuales. Estas pueden consistir, entre otras, en problemas de trofismo, asimetrías o distorsiones cicatriciales. Los injertos de tejido adiposo suponen una opción extremadamente válida y segura en los casos en los que estos pacientes solicitan una mejora estética de sus secuelas. Dado su potencial para crear volúmenes y para mejorar el trofismo de los tejidos afectados por diversas formas de fibrosis o atrofias, su utilidad debe ser considerada como una seria opción a considerar. Presentamos en este artículo 3 casos de reconstrucción estética del miembro inferior, por diversas causas, resueltos mediante el uso de injertos de tejido adiposo y revisados durante al menos un año. En todos ellos fueron necesarias al menos 2 sesiones para conseguir un resultado aceptable para el paciente. Abstract in english Lower extremity reconstruction is probably one of the most challenging and difficult disciplines in Plastic and Aesthetic Surgery. With independence of the original ethiology (postraumatic, oncologic or congenital), and after various surgical steps, this group of patients usually looks for some aest [...] hetic improvement of residual sequel. These may consist of diverse forms of trophic changes, asymmetries or distortions. Autologous fat grafting represent an extremely reliable and safe technique in those cases in which patients ask for some aesthetic improvement of their residual sequels. Due to their potential to create volumes and improve the quality of tissues affected from different kinds of atrophy or fibrosis, the use of fat grafting in these cases should be seriously considered as an alternative. Three cases of aesthetic improvement of lower extremity sequels of diverse origin and treated with autologous fat grafting are presented. The follow up period was at least of one year after last treatment. All of them needed at least 2 treatments to achieve an acceptable result for the patient.

J., Monreal..

2013-12-01

128

Utilidad del los injertos de tejido adiposo en la reconstrucción estética del miembro inferior / Use of autologous fat grafting in aesthetic lower extremity reconstruction  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish La reconstrucción del miembro inferior constituye, probablemente, una de las disciplinas más complejas y de más difícil ejecución en el ámbito de la Cirugía Plástica Estética, independientemente de la etiología inicial del problema (postraumática, oncológica o congénita) y, normalmente, tras varios [...] tratamientos quirúrgicos, el paciente puede solicitar la mejora estética de las secuelas residuales. Estas pueden consistir, entre otras, en problemas de trofismo, asimetrías o distorsiones cicatriciales. Los injertos de tejido adiposo suponen una opción extremadamente válida y segura en los casos en los que estos pacientes solicitan una mejora estética de sus secuelas. Dado su potencial para crear volúmenes y para mejorar el trofismo de los tejidos afectados por diversas formas de fibrosis o atrofias, su utilidad debe ser considerada como una seria opción a considerar. Presentamos en este artículo 3 casos de reconstrucción estética del miembro inferior, por diversas causas, resueltos mediante el uso de injertos de tejido adiposo y revisados durante al menos un año. En todos ellos fueron necesarias al menos 2 sesiones para conseguir un resultado aceptable para el paciente. Abstract in english Lower extremity reconstruction is probably one of the most challenging and difficult disciplines in Plastic and Aesthetic Surgery. With independence of the original ethiology (postraumatic, oncologic or congenital), and after various surgical steps, this group of patients usually looks for some aest [...] hetic improvement of residual sequel. These may consist of diverse forms of trophic changes, asymmetries or distortions. Autologous fat grafting represent an extremely reliable and safe technique in those cases in which patients ask for some aesthetic improvement of their residual sequels. Due to their potential to create volumes and improve the quality of tissues affected from different kinds of atrophy or fibrosis, the use of fat grafting in these cases should be seriously considered as an alternative. Three cases of aesthetic improvement of lower extremity sequels of diverse origin and treated with autologous fat grafting are presented. The follow up period was at least of one year after last treatment. All of them needed at least 2 treatments to achieve an acceptable result for the patient.

J., Monreal..

129

Oroantral communication closure using a pedicled buccal fat pad graft / Fechamento de comunicação buco-sinusal utilizando enxerto pediculado de corpo adiposo da bochecha  

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Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: O objetivo desde artigo foi relatar um caso clínico de fechamento de fístula buco-sinusal tardia utilizando rotação de enxerto de tecido adiposo pediculado do corpo adiposo da bochecha. DESCRIÇÃO DO CASO: Paciente do sexo masculino, 66 anos, leucoderma, em boas condições de saúde geral, fo [...] i encaminhado para fechamento de extensa comunicação buco-sinusal. Ao exame clínico, observou-se uma fístula de aproximadamente 10 mm de diâmetro comunicando a cavidade oral com o seio maxilar. A cirurgia foi realizada em nível ambulatorial, sob anestesia local, para fechar a fístula buco-sinusal com um enxerto de tecido adiposo pediculado do corpo adiposo da bochecha. A reparação da ferida e o fechamento do defeito foram observados no pós-operatório de 30 dias, com completa epitelização. CONCLUSÃO: O enxerto pediculado de tecido do corpo adiposo da bochecha mostrou-se uma alternativa simples, eficaz e segura no fechamento mediato da fístula buco-sinusal apresentada neste caso clínico. Abstract in english PURPOSE: This paper reports the procedure used to close a late oroantral fistula using rotating flaps of the pedicled buccal fat pad. CASE DESCRIPTION: A 66-year-old, male patient with leukoderma, in good general health, was referred for closure of an extensive late oroantral communication. Upon cli [...] nical examination, an approximately 10-mm fistula was observed connecting the oral cavity to the maxillary sinus. An outpatient surgical procedure was performed with the use of local anesthetics to close the oroantral fistula with a rotating pedicled buccal fat pad flap. The healing of the wound and closure of the defect could be seen after a 30-day postoperative period, with complete epithelialization. CONCLUSION: Grafting of the pedicled buccal fat pad is thought to be an efficient, safe and easy alternative to a larger oroantral fistula closure. Pedicled buccal fat pad grafting corrected the defect without generating any sequelae and/or great postoperative discomfort to the patient.

Ruy de Oliveira, Veras Filho; Fernando, Giovanella; Rafael Machado, Karsburg; Marcos Antonio, Torriani.

130

COMPARATIVE STUDY OF MANAGEMENT WITH MYRINGOPLASTY AND CHEMICAL CAUTERISATION IN TUBO-TYMPANIC TYPE OF CHRONIC SUPPURATIVE OTITIS MEDIA  

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Introduction CSOM is highly prevalent chronic ear disease. In developing countries like India, where tertiary medical facility is not available to all people, treatment should be cost effective and easily feasible at even primary health centre. With this background a study was performed for closure of small to moderate central perforation with chemical cauterisation and to see whether it is equally effective as that of Myringoplasty or not.Study design: prospective clinical study.Methodology:...

Shinde, Kiran J.; Amit Kumar Singh

2013-01-01

131

Uso da gordura e fáscia muscular autólogas no tratamento da insuficiência glótica Glottic insufficiency: the use of fat and fascia grafts  

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Full Text Available Uma das alterações mais complexas que acometem as pregas vocais é a incompetência ou insuficiência glótica. Pode ser causada por alterações de mobilidade, fibroses, atrofias ou arqueamento das pregas vocais, e pode levar, entre outras situações como aspiração e tosse pouco efetiva, a graus variados de disfonia. A partir do início do século 20, surgiram vários procedimentos cirúrgicos para a reabilitação da competência aerodinâmica e valvular da glote, por meio da injeção de substâncias heterólogas no espaço paraglótico. Os enxertos autólogos, como a gordura e a fáscia muscular, inseridos ou injetados nas pregas vocais inicialmente mostraram resultados promissores além de segurança e riscos mínimos de reações indesejadas. Neste artigo de revisão, os autores discutem o uso da gordura e da fáscia muscular na incompetência glótica, abordando aspectos históricos, o processo inflamatório gerado após a enxertia, as técnicas cirúrgicas mais utilizadas e o rendimento dos enxertos.Glottic insufficiency has been managed since the beginning of the twentieth century. The autologous grafts, as fat and muscular fascia, have shown safety and good results. The authors discuss the advantages and disadvantages of using fat and fascia in the management of glottic insufficiency, regarding historical aspects, inflammatory process and surgical techniques.

Christiano de Giacomo Carneiro

2006-02-01

132

Uso da gordura e fáscia muscular autólogas no tratamento da insuficiência glótica / Glottic insufficiency: the use of fat and fascia grafts  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Uma das alterações mais complexas que acometem as pregas vocais é a incompetência ou insuficiência glótica. Pode ser causada por alterações de mobilidade, fibroses, atrofias ou arqueamento das pregas vocais, e pode levar, entre outras situações como aspiração e tosse pouco efetiva, a graus variados [...] de disfonia. A partir do início do século 20, surgiram vários procedimentos cirúrgicos para a reabilitação da competência aerodinâmica e valvular da glote, por meio da injeção de substâncias heterólogas no espaço paraglótico. Os enxertos autólogos, como a gordura e a fáscia muscular, inseridos ou injetados nas pregas vocais inicialmente mostraram resultados promissores além de segurança e riscos mínimos de reações indesejadas. Neste artigo de revisão, os autores discutem o uso da gordura e da fáscia muscular na incompetência glótica, abordando aspectos históricos, o processo inflamatório gerado após a enxertia, as técnicas cirúrgicas mais utilizadas e o rendimento dos enxertos. Abstract in english Glottic insufficiency has been managed since the beginning of the twentieth century. The autologous grafts, as fat and muscular fascia, have shown safety and good results. The authors discuss the advantages and disadvantages of using fat and fascia in the management of glottic insufficiency, regardi [...] ng historical aspects, inflammatory process and surgical techniques.

Christiano de Giacomo, Carneiro; Domingos Hiroshi, Tsuji; Luiz Ubirajara, Sennes; João Aragão, Ximenes Filho; Rui, Imamura.

2006-02-01

133

De la biología al injerto de tejido adiposo: cómo mejorar el lipoinjerto / From biology to fat grafting: how to improve lipofilling  

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Full Text Available SciELO Spain | Language: Spanish Abstract in spanish A pesar de que el uso del injerto de grasa ha ganado popularidad, no hay consenso sobre la mejor manera de manejar el tejido adiposo. Los protocolos difieren y los resultados son a menudo variables. Diversos factores influyen en la calidad de la grasa inyectada, entre los que encontramos las molécul [...] as tóxicas provenientes de la infiltración, procedimiento previo a la liposucción. En este trabajo, hemos confirmado el efecto nocivo de los anestésicos sobre las células madre derivadas del tejido adiposo, determinando el efecto del lavado y la centrifugación en el tejido graso con el fin de proponer un protocolo simple y optimizado para mejorar la supervivencia del injerto. Evaluamos la citotoxicidad de la lidocaína sobre las células madre derivadas de tejido adiposo (ADSC) mediante ensayo de LDH. Sometimos el tejido adiposo conjunto a varios tipos de centrifugación (de 1 segundo a 10 minutos y desde 0 g a 1800 g), y el volumen de líquido y el aceite liberado se midió inmediatamente después de la centrifugación. Tras la determinación de las condiciones óptimas para la manipulación de tejidos (400 g/1 minuto), inyectamos el tejido adiposo de liposucción sin o con lidocaína en ratones inmunodeficientes. Un mes después de la inyección, evaluamos la calidad de los injertos mediante histología, y en comparación con los injertos obtenidos a partir de un protocolo convencional: una simple sedimentación. La lidocaína ejerce un efecto citotóxico sobre las ADSC, y este efecto depende del tiempo de incubación y de las concentraciones. En cuanto al tejido adiposo, una centrifugación intensa (900 g, 1800 g) es perjudicial en comparación con una centrifugación suave (100 g, 400 g). Además, las secciones histológicas de los injertos de tejido adiposo no centrifugados mostraron la presencia de grandes vacuolas de aceite mientras que los injertos resultantes de lavado con protocolo de centrifugación suave (400g/1minuto) no lo hacen. En conclusión, creemos que se debe emplear un manejo adecuado del tejido adiposo, incluyendo lavado y centrifugación, con el fin de eliminar el líquido de infiltración y las moléculas tóxicas asociadas que son perjudiciales para los injertos. Sin embargo, no recomendamos una centrifugación intensa ya que conduce muy rápidamente a una mayor muerte celular. Por lo tanto, una centrifugación suave (400 g/1 minuto) precedida de lavados, parece ser el protocolo más apropiado para la reinyección del tejido adiposo. Abstract in english While fat grafting for soft tissue filling has gained popularity, there is no consensus on the best way how to handle adipose tissue. Protocols differ and results are often highly variable. Various factors influence the quality of injected fat, among which the toxic molecules coming from infiltratio [...] n procedure prior to liposuction. In this work, we have confirmed the deleterious effect of anesthetics on adipose-derived stem cells, and determined the effect of washing and centrifugation on adipose tissue, in order to propose a simple and optimized protocol to improve graft survival. Lidocaine cytotoxicity on adipose-derived stem cells (ADSCs) was evaluated by LDH assay. Then, whole adipose tissue was subjected to various centrifugation types (from 1 sec to 10 min and from 0 g to 1800 g), and volume of liquid and oil released were measured immediately after centrifugation. After determination of the optimal conditions for tissue handling (400 g/1 min), adipose tissue from liposuction made without or with lidocaine was injected into immunodeficient mice. One month after injection, quality of the grafts was evaluated by histology, and compared with grafts obtained from one conventional protocol: a simple settling. Lidocaine exerts a cytotoxic effect on ADSCs, and this effect is dependent on the incubation time and concentrations. Concerning adipose tissue, strong centrifugation (900 g, 1800 g) is deleterious compared to the low centrifugation (100 g, 400 g). In add

A.C., Girard; S., Mirbeau; M., Atlan; F., Festy; R., Roche; L., Hoareau.

2013-12-01

134

Experiencia en miringoplastía transcanal con pericondrio tragai inlay / Experience in transcanal myringoplasty with inlay tragal perichondrium  

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Full Text Available SciELO Chile | Language: Spanish Abstract in spanish Introducción: La timpanoplastía está orientada a la reconstrucción anatomofuncional del oído medio que realizada en la membrana timpánica se denomina miringoplastía. Objetivo: Evaluar los resultados anatomofuncionales de la miringoplastía transcanal con pericondrio tragal inlay en pacientes interven [...] idos en el Servicio de Otorrinolaringología del Hospital San Camilo entre 2004 y 2009. Material y método: Estudio retrospectivo descriptivo de fichas de 56 pacientes entre 7 y 77 años. Universo: 60 oídos, muestra: 48 oídos con edad promedio de 34 años. Se evaluaron resultados anatómicos según sexo, edad, ubicación, causa de perforación y mejoría funcional objetivada por audiometría. Resultados: La integridad anatómica posquirúrgica es de 81,3% sin diferencias según género. Según edad existe diferencia significativa de 93,3% para el tramo 7-19 años respecto del total. Las perforaciones centrales tuvieron un éxito de 100%. La causa más frecuente de perforación fue por otitis media crónica simple (75%) con una integridad posquirúrgica del 80,5%. El 97,6% logró mejorar o mantener el nivel de audición, estableciéndose diferencialmente mejoría funcional en 52,4%, y una mantención en 45,2%. Conclusión: Los mejores resultados para esta técnica se obtienen en menores de 20 años con perforaciones centrales, siendo una técnica ideal que conserva la estructura de la membrana timpánica para futuras intervenciones. Abstract in english Introduction: Tympanoplasty is orientated to the anatomofunctional reconstruction of the middle ear, which is named myringoplasty, when performed in the tympanic membrane. Aim: To evaluate the anatomofunctional results of transcanal myringoplasty with inlay tragal perichondrium in patients controlle [...] d in the Otorhinolaryngology Unit of San Camilo Hospital, between 2004 and 2009. Material and method: Retrospective descriptive study on files of 56 patients between 7 and 77 years of age. Universe: 60 ears, sample: 48 ears with average age 34 years. Anatomical results were evaluated according to sex, age, location, cause of perforation and functional improvement measured by audiometry. Results: The overall anatomical postsurgical integrity is 81,3 % without differences between sexes. According to age there is a significant difference for the section between 7-19 years of age respect of the total (93,3 %). Central perforations had a 100% success rate. The most frequent reason of perforation was simple chronic otitis media (75%) with a postsurgical integrity of 80,5 %. 97,6 % managed to improve or maintain hearing level, (52,4 % gained functional improvement, and 45,2 % maintained hearing level). Conclusion: Using this technique, best results are obtained in patients younger than 20 years of age, with central perforations. It is an ideal method that preserves the structure of the tympanic membrane for future interventions.

Mauricio, Calderón R; Carmen, Meléndez P; Cristian, Morales S; Danisa, Torres M.

2012-08-01

135

Utilización de injerto dermo-graso en pacientes con retracción de la cavidad anoftálmica Use of dermis fat graft in patients with retraction of the anophthalmic cavity  

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Full Text Available Se realizó un estudio descriptivo en 45 pacientes con cavidades retraídas que fueron operados con injerto dermo-graso en el período comprendido entre enero de 1999 y diciembre de 2002. A todos se les tomaron los siguientes datos: tiempo de uso de la prótesis ocular, examen de la cavidad, calidad del injerto y causas de retracción del injerto en los casos de evolución no favorables. Los pacientes entre los 31 y los 60 años de edad, ocuparon el 42 %. Al analizar las causas de pérdida del globo ocular se encontró que los traumatismos por accidente laboral ocuparon un 28,9 %. Con respecto al tiempo de uso de la prótesis ocular se aprecia que el 40 % tenía más de 7 años de uso. Dentro de los datos recogidos existió retracción del fórnix inferior en el 46,6 %. Al estudiar las causas de retracción de la cavidad el 51,1 % presentó infecciones e inflamaciones. El 82,2 % no presentó complicaciones y entre las causas del resultado quirúrgico no satisfactorio la infección sobreañadida ocupó un 50 %.A descriptive study was conducted in 45 patients with retracted cavities that were operated on with dermis fat graft from January, 1999, to December, 2002. The following data were collected: time of use of the ocular prosthesis, cavity examination, graft quality and causes of graft retraction.in those cases with unfavorable evolution. The patients aged 31-60 accounted for 42 %. On analyzing the causes of the loss of the eyeball it was found that traumatisms due to working accidents represented 28.9 %. As regards the time of use of the ocular prosthesis, it was observed that 40 % had been used for more than 7 years. Among the collected data, there was retraction of the lower fornix in 46.6 %. On studying the causes of the retraction of the cavity, 51.1 % presented infections and inflammations. 82.2 % had no complications and among the causes of the unsatisfactory surgical result, it was observed 50 % of overadded infection.

Marta Herrera Soto

2003-12-01

136

Utilización de injerto dermo-graso en pacientes con retracción de la cavidad anoftálmica / Use of dermis fat graft in patients with retraction of the anophthalmic cavity  

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Full Text Available SciELO Cuba | Language: Spanish Abstract in spanish Se realizó un estudio descriptivo en 45 pacientes con cavidades retraídas que fueron operados con injerto dermo-graso en el período comprendido entre enero de 1999 y diciembre de 2002. A todos se les tomaron los siguientes datos: tiempo de uso de la prótesis ocular, examen de la cavidad, calidad del [...] injerto y causas de retracción del injerto en los casos de evolución no favorables. Los pacientes entre los 31 y los 60 años de edad, ocuparon el 42 %. Al analizar las causas de pérdida del globo ocular se encontró que los traumatismos por accidente laboral ocuparon un 28,9 %. Con respecto al tiempo de uso de la prótesis ocular se aprecia que el 40 % tenía más de 7 años de uso. Dentro de los datos recogidos existió retracción del fórnix inferior en el 46,6 %. Al estudiar las causas de retracción de la cavidad el 51,1 % presentó infecciones e inflamaciones. El 82,2 % no presentó complicaciones y entre las causas del resultado quirúrgico no satisfactorio la infección sobreañadida ocupó un 50 %. Abstract in english A descriptive study was conducted in 45 patients with retracted cavities that were operated on with dermis fat graft from January, 1999, to December, 2002. The following data were collected: time of use of the ocular prosthesis, cavity examination, graft quality and causes of graft retraction.in tho [...] se cases with unfavorable evolution. The patients aged 31-60 accounted for 42 %. On analyzing the causes of the loss of the eyeball it was found that traumatisms due to working accidents represented 28.9 %. As regards the time of use of the ocular prosthesis, it was observed that 40 % had been used for more than 7 years. Among the collected data, there was retraction of the lower fornix in 46.6 %. On studying the causes of the retraction of the cavity, 51.1 % presented infections and inflammations. 82.2 % had no complications and among the causes of the unsatisfactory surgical result, it was observed 50 % of overadded infection.

Marta, Herrera Soto; Iraida, Falcón Márquez; Ileana, Agramonte Centelles; Clara, Gómez Cabrera.

137

Use of dermal-fat grafts in the post-oncological reconstructive surgery of atrophies in the zygomatic region: clinical evaluations in the patients undergone to previous radiation therapy  

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Full Text Available Abstract Introduction Grafting of autologous adipose tissue can be recommended in some cases of facial plastic surgery. Rhabdomyosarcoma is a type of cancer that can also affect the orbit. Enucleation of the eye can cause atrophy of the corresponding hemiface and decreased orbital growth. Case report We report a case of a female patient with a medical history of surgical enucleation of the right eyeball, who had received rhabdomyosarcoma radiation therapy in her youth. The patient presented with a depression in the right zygomatic region. We took a dermal-fat flap from the abdominal region, which had been previously treated. Results The surgical outcome, 48 hours, and much clearly 31 days after the surgery, revealed that the right zygomatic region had returned to its proper anatomical shape, although there were still signs of postoperative edema. Discussion Very damaged tissues, like those exposed to radiation therapy, are generally not suitable for grafting of adipose tissue. Conclusions In the described case, we achieved a technically and aesthetically satisfying result despite the patient's medical history involving several perplexities about the use of autologous dermal-fat tissues, because of prior radiation therapy exposure. The clinical case shows that even a region exposed to radiation therapy can be a valid receiving bed for dermal-fat grafting.

Inchingolo Francesco

2012-12-01

138

Lipoenxertia autóloga periorbitária no rejuvenescimento facial: análise retrospectiva da eficácia e da segurança em 31 casos Autologous periorbital fat grafting in facial rejuvenation: a retrospective analysis of efficacy and safety in 31 cases  

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Full Text Available INTRODUÇÃO: Os sulcos periorbitários e zigomático e o malar flácido estão entre as características mais marcantes de envelhecimento ou de desarmonia facial. A reposição do volume é um método simples e eficiente, e o lipoenxerto pode ser o melhor material. O presente trabalho traz uma análise de 31 pacientes submetidos a autolipoenxertia, com ênfase na eficácia e na segurança da técnica. MÉTODO: Análise retrospectiva de 31 pacientes consecutivos, submetidos a lipoenxertias periorbitária e malar, concomitantemente ou não a outros procedimentos estéticos. A avaliação foi feita por meio de comparação entre fotografias pré e pós-operatória, bem como pelo grau de satisfação dos pacientes. RESULTADOS: Dos 31 pacientes, 26 (83,9% classificaram o resultado pós-operatório como ótimo, 3 (9,7%, bom, e 2 (6,4%, regular. Na avaliação dos autores, 24 (77,5% pacientes apresentaram resultado ótimo, 5 (16,1%, bom, e 2 (6,4%, regular. Houve necessidade de retoque de lipoenxertia em apenas 4 pacientes, por sugestão do cirurgião. As complicações foram mínimas e passageiras. CONCLUSÕES: A lipoenxertia facial é fácil e eficaz, e as complicações são mínimas quando realizada por cirurgiões qualificados.BACKGROUND: Periorbital and zygomatic hollows as well as flaccid cheeks are among the most evident characteristics of aging or facial disharmony. Volume replacement is a simple and efficient procedure, and fat grafting is considered as the best treatment for these characteristics. This study evaluates 31 patients who underwent autologous fat grafting and emphasizes the safety and efficacy of this procedure. METHODS: A retrospective analysis of 31 consecutive patients who underwent periorbital and zygomatic fat grafting, alone or in combination with other cosmetic procedures, was carried out. Final evaluation was performed by assessing pre- and postoperative photographs as well as the degree of patient satisfaction. RESULTS: Of 31 patients, 26 (83.9% reported excellent postoperative outcomes; 3 (9.7%, satisfactory outcomes; and 2 (6.4%, poor outcomes. According to the authors' evaluation, 24 (77.5% patients had excellent outcomes, 5 (16.1% had satisfactory outcomes, and 2 (6.4% had poor outcomes. Retouching of the fat graft was recommended for only 4 patients. The complications observed were minimal and transient. CONCLUSIONS: Facial fat grafting is a simple and effective procedure that presents minimal complications when performed by skilled surgeons.

Chang Yung Chia

2012-09-01

139

Lipoenxertia autóloga periorbitária no rejuvenescimento facial: análise retrospectiva da eficácia e da segurança em 31 casos / Autologous periorbital fat grafting in facial rejuvenation: a retrospective analysis of efficacy and safety in 31 cases  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese INTRODUÇÃO: Os sulcos periorbitários e zigomático e o malar flácido estão entre as características mais marcantes de envelhecimento ou de desarmonia facial. A reposição do volume é um método simples e eficiente, e o lipoenxerto pode ser o melhor material. O presente trabalho traz uma análise de 31 p [...] acientes submetidos a autolipoenxertia, com ênfase na eficácia e na segurança da técnica. MÉTODO: Análise retrospectiva de 31 pacientes consecutivos, submetidos a lipoenxertias periorbitária e malar, concomitantemente ou não a outros procedimentos estéticos. A avaliação foi feita por meio de comparação entre fotografias pré e pós-operatória, bem como pelo grau de satisfação dos pacientes. RESULTADOS: Dos 31 pacientes, 26 (83,9%) classificaram o resultado pós-operatório como ótimo, 3 (9,7%), bom, e 2 (6,4%), regular. Na avaliação dos autores, 24 (77,5%) pacientes apresentaram resultado ótimo, 5 (16,1%), bom, e 2 (6,4%), regular. Houve necessidade de retoque de lipoenxertia em apenas 4 pacientes, por sugestão do cirurgião. As complicações foram mínimas e passageiras. CONCLUSÕES: A lipoenxertia facial é fácil e eficaz, e as complicações são mínimas quando realizada por cirurgiões qualificados. Abstract in english BACKGROUND: Periorbital and zygomatic hollows as well as flaccid cheeks are among the most evident characteristics of aging or facial disharmony. Volume replacement is a simple and efficient procedure, and fat grafting is considered as the best treatment for these characteristics. This study evaluat [...] es 31 patients who underwent autologous fat grafting and emphasizes the safety and efficacy of this procedure. METHODS: A retrospective analysis of 31 consecutive patients who underwent periorbital and zygomatic fat grafting, alone or in combination with other cosmetic procedures, was carried out. Final evaluation was performed by assessing pre- and postoperative photographs as well as the degree of patient satisfaction. RESULTS: Of 31 patients, 26 (83.9%) reported excellent postoperative outcomes; 3 (9.7%), satisfactory outcomes; and 2 (6.4%), poor outcomes. According to the authors' evaluation, 24 (77.5%) patients had excellent outcomes, 5 (16.1%) had satisfactory outcomes, and 2 (6.4%) had poor outcomes. Retouching of the fat graft was recommended for only 4 patients. The complications observed were minimal and transient. CONCLUSIONS: Facial fat grafting is a simple and effective procedure that presents minimal complications when performed by skilled surgeons.

Chang Yung, Chia; Diego Antonio, Rovaris.

140

Lipoenxertia autóloga periorbitária no rejuvenescimento facial: análise retrospectiva da eficácia e da segurança em 31 casos / Autologous periorbital fat grafting in facial rejuvenation: a retrospective analysis of efficacy and safety in 31 cases  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese INTRODUÇÃO: Os sulcos periorbitários e zigomático e o malar flácido estão entre as características mais marcantes de envelhecimento ou de desarmonia facial. A reposição do volume é um método simples e eficiente, e o lipoenxerto pode ser o melhor material. O presente trabalho traz uma análise de 31 p [...] acientes submetidos a autolipoenxertia, com ênfase na eficácia e na segurança da técnica. MÉTODO: Análise retrospectiva de 31 pacientes consecutivos, submetidos a lipoenxertias periorbitária e malar, concomitantemente ou não a outros procedimentos estéticos. A avaliação foi feita por meio de comparação entre fotografias pré e pós-operatória, bem como pelo grau de satisfação dos pacientes. RESULTADOS: Dos 31 pacientes, 26 (83,9%) classificaram o resultado pós-operatório como ótimo, 3 (9,7%), bom, e 2 (6,4%), regular. Na avaliação dos autores, 24 (77,5%) pacientes apresentaram resultado ótimo, 5 (16,1%), bom, e 2 (6,4%), regular. Houve necessidade de retoque de lipoenxertia em apenas 4 pacientes, por sugestão do cirurgião. As complicações foram mínimas e passageiras. CONCLUSÕES: A lipoenxertia facial é fácil e eficaz, e as complicações são mínimas quando realizada por cirurgiões qualificados. Abstract in english BACKGROUND: Periorbital and zygomatic hollows as well as flaccid cheeks are among the most evident characteristics of aging or facial disharmony. Volume replacement is a simple and efficient procedure, and fat grafting is considered as the best treatment for these characteristics. This study evaluat [...] es 31 patients who underwent autologous fat grafting and emphasizes the safety and efficacy of this procedure. METHODS: A retrospective analysis of 31 consecutive patients who underwent periorbital and zygomatic fat grafting, alone or in combination with other cosmetic procedures, was carried out. Final evaluation was performed by assessing pre- and postoperative photographs as well as the degree of patient satisfaction. RESULTS: Of 31 patients, 26 (83.9%) reported excellent postoperative outcomes; 3 (9.7%), satisfactory outcomes; and 2 (6.4%), poor outcomes. According to the authors' evaluation, 24 (77.5%) patients had excellent outcomes, 5 (16.1%) had satisfactory outcomes, and 2 (6.4%) had poor outcomes. Retouching of the fat graft was recommended for only 4 patients. The complications observed were minimal and transient. CONCLUSIONS: Facial fat grafting is a simple and effective procedure that presents minimal complications when performed by skilled surgeons.

Chang Yung, Chia; Diego Antonio, Rovaris.

2012-09-01

 
 
 
 
141

Uso de factores de crecimiento plaquetar unidos a injertos de grasa para lipofiling facial en ritidectomía Use of fat grafts enriched with platelet growth factors for facial lipofiling in ritidectomy  

Directory of Open Access Journals (Sweden)

Full Text Available Presentamos una serie de pacientes a los que hemos realizado infiltraciones de grasa enriquecida con Factores de Crecimiento Plaquetario (F.C.P. como único procedimiento. Igualmente presentamos casos donde las infiltraciones van acompañadas con otros procedimientos (lifting temporal, lifting cérvico-frontal, etc.. También usamos el plasma rico en F.C.P. en forma de coágulo para rellenar el surco de la cuenca orbitaria (“Tear Through”, y como mesoterapia facial enriquecida con nutrientes. El objetivo de este trabajo es presentar una revisión detallada de los pasos a seguir para la realización de éste procedimiento, que van desde la simple extracción de sangre para la posterior obtención de F.C.P. hasta la técnica de infiltración de grasa enriquecida con dichos factores a nivel facial. Con esta técnica de enriquecimiento de la grasa hemos logrado tener mejores resultados y con mayor permanencia. Evaluando los postoperatorios de pacientes sometidos a este procedimiento, hemos observado que el volumen infiltrado en áreas como la región malar, se mantiene entre un 90% a 95%. En otras áreas como labios y surcos nasogenianos (áreas de gran movilidad, solo permanece entre el 50% a 60% del volumen infiltrado.We present a serie of patients with facial fat infiltration enriched with platelet-derived growth factors, some of them associated to other surgical procedures (temporal lifting, cervico-frontal lifting, etc. We explain how to use this platelet - rich plasma to fill the tear - through and as a facial mesotherapy. Our purpose is to present a detailled review of our method: since blood extraction to the last obtention of the platelet - derived growth factors and the use of this plasma combined with fat infiltration in the facial area. With this methodology we have got better and more permanent results. We have evaluated 90-95 % fat grafts survival in malar region. In other facial areas such as lips or nasogenian folds (big movement areas, we only report about 50 to 60% fat graft survival.

J.M. Serra Renom

2006-09-01

142

Injertos de tejido adiposo: variables que influyen en la viabilidad del adipocito y de las células madre mesenquimales Fat grafting: variables that influence the viability of the adipocyte and mesenchimal stem cells  

Directory of Open Access Journals (Sweden)

Full Text Available Si bien los injertos de tejido adiposo se han venido utilizando durante décadas a lo largo del siglo pasado, la técnica se venía considerando como poco útil dado que el injerto tendía a la reabsorción. Fue Coleman quien introdujo un sistema de obtención-procesamiento-infiltración atraumático que aumentó el porcentaje de supervivencia del injerto y la obtención de resultados positivos similares en su aplicación en todo el mundo. Aún así, la publicación de resultados dispares en la literatura respecto a la supervivencia del injerto, con diferentes porcentajes de reabsorción y el descubrimiento de las células madre en el tejido adiposo, han llevado a la realización de numerosos trabajos de investigación encaminados a comprender la biología del injerto de tejido adiposo, a estudiar el papel de las células madre en este proceso y la influencia que sobre la viabilidad celular tienen los distintos pasos a los que los cirujanos plásticos sometemos al tejido adiposo para su trasplante. Hemos hecho una revisión de la literatura científica al respecto para reunir la información disponible sobre estas controversias.Though adipose tissue grafts have been used for decades in last century, the technique has been considered as slightly usefull provided that the graft was tending to reabsorption. It was Coleman who introduced a system of atraumatic harvesting-processing-infiltration that increased the percentage of survival of the graft obtaining positive similar results in its application all over the world. Nonetheless, publication of unlike results in the literature regarding survival of the graft with different percentages of reabsorption and the discovery of stem cells in the adipose tissue, have led to the accomplishment of numerous research works directed to understanding the biology of the fat graft, the role of the stem cells in this process and the influence that the different steps for transplantation have on the cellular viability. We present a review of the scientific literature about the theme to bring together the available information about these controversies.

J. Benito Ruiz

2011-12-01

143

¿Cuál es la supervivencia de los injertos de grasa en la cara? ¿Cómo cuantificarla?: medicina basada en la evidencia / Which is the survival of fat grafts on the face? How to quantify it?: evidence based medicine  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish Muchos de los artículos publicados acerca del éxito de los injertos autólogos de grasa (IAG) en humanos son muy subjetivos o, en el mejor de los casos, semicuantitativos Hasta hoy, se necesitan estudios adicionales, tanto clínicos como básicos, antes de que podamos llegar a precisar el valor de esta [...] técnica. Diseñamos un estudio prospectivo y randomizado con el objetivo de cuantificar la supervivencia de los autoinjertos de grasa en cara, en una serie seleccionada de 71 pacientes con defectos subcutáneos de partes blandas faciales que cumplieron criterios de inclusión, en dos grupos, según fueran casos de Cirugía Reconstructiva o de Cirugía Estética. El procedimiento quirúrgico estándar empleado fue la técnica de lipoestructura facial; se tomó biopsia del tejido adiposo injertado a los 14 meses de seguimiento. Empleamos el método estereológico para medir los parámetros volumétricos cuantitativos de la grasa en el momento de la inyección y en el momento de la biopsia. Por medio de simples ecuaciones matemáticas, pudimos extraer las tasas de prendimiento tanto volumétrica como numérica. También se practicaron análisis estadísticos descriptivos y cuantitativos de todos los datos. Los injertos de grasa autólogos en la cara sobreviven en dos tercios del volumen inyectado a los 14 meses de seguimiento. La única prueba confirmatoria de supervivencia de los autoin-jertos de grasa es la evidencia y demostración histológica de tejido adiposo viable en las zonas receptoras y su cuantificación mediante un método de evaluación volumétrico, preciso y objetivo, como el que permite la Estereología. Abstract in english Many reports concerning the success of fat auto-grafts in humans are widely subjective or semi-quantitative in best of cases. Even today, additional studies, clinical or basic, are ne-cessary before the value of this technique can be calculated. With the aim of quantifying the survival of fat auto-g [...] rafts on the face, a prospective randomized study was designed, selecting 71 patients suffering facial soft tissue subcutaneous defects fulfilling the inclusion criteria. Two groups were descri-bed according to reconstructive and aesthetic surgery. Facial lipostructure technique was used as the standard surgical procedure and a biopsy of the grafted adipose tissue was taken at 14 months follow-up. The stereological method was used to measure the quantitative volumetric parameters of the fat at the injection time and at the biopsy time. By means of simple mathematical equations, the volumetric and numerical take rate could be obtained. Descriptive and quantitative statistical analyses of all data were performed. Fat auto-grafts on the face survive two thirds of the injec-ted volume at 14 months follow-up. The unique confirmation proof of survival of fat auto-grafts is the histological evidence and demonstration of viable adipose tissue in recipient sites and its quantification by a volumetric, accurate and objective valuation method, as it is provided by Stereology.

E., Serna-Cuéllar; L., Santamaría-Solís.

2013-12-01

144

Uso de factores de crecimiento plaquetar unidos a injertos de grasa para lipofiling facial en ritidectomía / Use of fat grafts enriched with platelet growth factors for facial lipofiling in ritidectomy  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish Presentamos una serie de pacientes a los que hemos realizado infiltraciones de grasa enriquecida con Factores de Crecimiento Plaquetario (F.C.P.) como único procedimiento. Igualmente presentamos casos donde las infiltraciones van acompañadas con otros procedimientos (lifting temporal, lifting cérvic [...] o-frontal, etc.). También usamos el plasma rico en F.C.P. en forma de coágulo para rellenar el surco de la cuenca orbitaria (“Tear Through”), y como mesoterapia facial enriquecida con nutrientes. El objetivo de este trabajo es presentar una revisión detallada de los pasos a seguir para la realización de éste procedimiento, que van desde la simple extracción de sangre para la posterior obtención de F.C.P. hasta la técnica de infiltración de grasa enriquecida con dichos factores a nivel facial. Con esta técnica de enriquecimiento de la grasa hemos logrado tener mejores resultados y con mayor permanencia. Evaluando los postoperatorios de pacientes sometidos a este procedimiento, hemos observado que el volumen infiltrado en áreas como la región malar, se mantiene entre un 90% a 95%. En otras áreas como labios y surcos nasogenianos (áreas de gran movilidad), solo permanece entre el 50% a 60% del volumen infiltrado. Abstract in english We present a serie of patients with facial fat infiltration enriched with platelet-derived growth factors, some of them associated to other surgical procedures (temporal lifting, cervico-frontal lifting, etc.) We explain how to use this platelet - rich plasma to fill the tear - through and as a faci [...] al mesotherapy. Our purpose is to present a detailled review of our method: since blood extraction to the last obtention of the platelet - derived growth factors and the use of this plasma combined with fat infiltration in the facial area. With this methodology we have got better and more permanent results. We have evaluated 90-95 % fat grafts survival in malar region. In other facial areas such as lips or nasogenian folds (big movement areas), we only report about 50 to 60% fat graft survival.

J.M., Serra Renom; J.L., Muñoz del Olmo; C., Gonzalo Caballero.

145

Injertos de tejido adiposo: variables que influyen en la viabilidad del adipocito y de las células madre mesenquimales / Fat grafting: variables that influence the viability of the adipocyte and mesenchimal stem cells  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish Si bien los injertos de tejido adiposo se han venido utilizando durante décadas a lo largo del siglo pasado, la técnica se venía considerando como poco útil dado que el injerto tendía a la reabsorción. Fue Coleman quien introdujo un sistema de obtención-procesamiento-infiltración atraumático que aum [...] entó el porcentaje de supervivencia del injerto y la obtención de resultados positivos similares en su aplicación en todo el mundo. Aún así, la publicación de resultados dispares en la literatura respecto a la supervivencia del injerto, con diferentes porcentajes de reabsorción y el descubrimiento de las células madre en el tejido adiposo, han llevado a la realización de numerosos trabajos de investigación encaminados a comprender la biología del injerto de tejido adiposo, a estudiar el papel de las células madre en este proceso y la influencia que sobre la viabilidad celular tienen los distintos pasos a los que los cirujanos plásticos sometemos al tejido adiposo para su trasplante. Hemos hecho una revisión de la literatura científica al respecto para reunir la información disponible sobre estas controversias. Abstract in english Though adipose tissue grafts have been used for decades in last century, the technique has been considered as slightly usefull provided that the graft was tending to reabsorption. It was Coleman who introduced a system of atraumatic harvesting-processing-infiltration that increased the percentage of [...] survival of the graft obtaining positive similar results in its application all over the world. Nonetheless, publication of unlike results in the literature regarding survival of the graft with different percentages of reabsorption and the discovery of stem cells in the adipose tissue, have led to the accomplishment of numerous research works directed to understanding the biology of the fat graft, the role of the stem cells in this process and the influence that the different steps for transplantation have on the cellular viability. We present a review of the scientific literature about the theme to bring together the available information about these controversies.

J., Benito Ruiz.

146

Injertos de tejido adiposo: variables que influyen en la viabilidad del adipocito y de las células madre mesenquimales / Fat grafting: variables that influence the viability of the adipocyte and mesenchimal stem cells  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish Si bien los injertos de tejido adiposo se han venido utilizando durante décadas a lo largo del siglo pasado, la técnica se venía considerando como poco útil dado que el injerto tendía a la reabsorción. Fue Coleman quien introdujo un sistema de obtención-procesamiento-infiltración atraumático que aum [...] entó el porcentaje de supervivencia del injerto y la obtención de resultados positivos similares en su aplicación en todo el mundo. Aún así, la publicación de resultados dispares en la literatura respecto a la supervivencia del injerto, con diferentes porcentajes de reabsorción y el descubrimiento de las células madre en el tejido adiposo, han llevado a la realización de numerosos trabajos de investigación encaminados a comprender la biología del injerto de tejido adiposo, a estudiar el papel de las células madre en este proceso y la influencia que sobre la viabilidad celular tienen los distintos pasos a los que los cirujanos plásticos sometemos al tejido adiposo para su trasplante. Hemos hecho una revisión de la literatura científica al respecto para reunir la información disponible sobre estas controversias. Abstract in english Though adipose tissue grafts have been used for decades in last century, the technique has been considered as slightly usefull provided that the graft was tending to reabsorption. It was Coleman who introduced a system of atraumatic harvesting-processing-infiltration that increased the percentage of [...] survival of the graft obtaining positive similar results in its application all over the world. Nonetheless, publication of unlike results in the literature regarding survival of the graft with different percentages of reabsorption and the discovery of stem cells in the adipose tissue, have led to the accomplishment of numerous research works directed to understanding the biology of the fat graft, the role of the stem cells in this process and the influence that the different steps for transplantation have on the cellular viability. We present a review of the scientific literature about the theme to bring together the available information about these controversies.

J., Benito Ruiz.

2011-12-01

147

Dietary Fat  

Science.gov (United States)

... Nutrition for Everyone Nutrition Topics Share Compartir Dietary Fat What counts as fat? Are some fats better ... polyunsaturated and monounsaturated fats. How much total dietary fat do I need? The Dietary Guidelines for Americans ...

148

Fat Substitutes  

Science.gov (United States)

... Fit-Friendly Worksites Program Requirements Fit-Friendly Resources Fat Substitutes Updated:Mar 18,2014 AHA Recommendation We ... including a variety of foods low in saturated fat, trans fat, cholesterol and sodium. What are fat ...

149

Saturated Fat  

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... Nutrition for Everyone Nutrition Topics Share Compartir Saturated Fat You may have heard that saturated fats are ... coconut oil. How do I control my saturated fat intake? In general, saturated fat can be found ...

150

Fat test  

Science.gov (United States)

Nutrients include fats, protein, minerals, water, and carbohydrates. Brown paper can be used as an indicator of how much fat is in a food. The food that makes the largest grease spot has the most fat.

Olivia Worland (Purdue University;Biological Sciences)

2008-06-06

151

Facial Soft Tissue Augmentation using Autologous Fat Mixed with Stromal Vascular Fraction  

Directory of Open Access Journals (Sweden)

Full Text Available Background Autologous fat grafting evolved over the twentieth century to become a quick,safe, and reliable method for restoring volume. However, autologous fat grafts have someproblems including uncertain viability of the grafted fat and a low rate of graft survival. Toovercome the problems associated with autologous fat grafts, we used uncultured adiposetissue-derived stromal cell (stromal vascular fraction, SVF assisted autologous fat grafting.Thus, the purpose of this study was to evaluate the effect of SVF in a clinical trial.Methods SVF cells were freshly isolated from half of the aspirated fat and were used incombination with the other half of the aspirated fat during the procedure. Between March2007 and February 2008, a total of 9 SVF-assisted fat grafts were performed in 9 patients.The patients were followed for 12 weeks after treatment. Data collected at each follow-upvisit included clinical examination of the graft site(s, photographs for historical comparison,and information from a patient questionnaire that measured the outcomes from the patientperspective. The photographs were evaluated by medical professionals.Results Scores of the left facial area grafted with adipose tissue mixed with SVF cells weresignificantly higher compared with those of the right facial area grafted with adipose tissuewithout SVF cells. There was no significant adverse effect.Conclusions The subjective patient satisfaction survey and surgeon survey showed that SVFassistedfat grafting was a surgical procedure with superior results.

Sang Kyun Lee

2012-09-01

152

Pancreas grafts  

International Nuclear Information System (INIS)

Perfusion studies with sup(99m)Tc-DTPA, which has hitherto been used routinely to investigate renal grafts, have also proved useful for monitoring the perfusion of pancreas grafts. A total perfusion failure is equally reliably demonstrable as in renal grafts. Quantitatively smaller perfusion alterations can be demonstrated by monitoring the course. It seems possible to differentiate the salivary edema of a rejection reaction, well known from animal experiments, with the help of other paramters (e.g. creatinine). Further clinical studies are however necessary to confirm these results. (orig.)

153

Polyunsaturated Fats and Monounsaturated Fats  

Science.gov (United States)

... Polyunsaturated Fat Sources Nuts Vegetable oils Canola oil Olive oil High oleic safflower oil Sunflower oil Avocado Soybean ... Polyunsaturated Fat Sources Nuts Vegetable oils Canola oil Olive oil High oleic safflower oil Sunflower oil Avocado Soybean ...

154

Dietary Fats  

Science.gov (United States)

... Saturated fats such as butter, solid shortening, and lard. Trans fats. These are found in vegetable shortenings, some margarines, crackers, cookies, snack foods, and other foods made with or fried in partially hydrogenated oils. Try to replace them with oils such as ...

155

Trans Fat  

Science.gov (United States)

... still consume 1.3 grams (0.6% of energy) of artificial trans fat each day. 4 Major contributors to artificial trans fat intake include fried items, savory snacks (like microwave popcorn), frozen pizzas, cake, cookies, pie, margarines and spreads, ready- ...

156

Bone Graft Alternatives  

Science.gov (United States)

... deformity or during a surgical procedure such as spinal fusion. What Types of Bone Grafts are There? Bone ... of bone grafts in spine surgery is during spinal fusion. The use of autogenous bone grafts for spinal ...

157

Dietary Fat and Cholesterol  

Science.gov (United States)

Dietary Fat and Cholesterol Posted under Health Guides . Updated 10 December 2012. +Related Content Key Facts Unsaturated fats (both ... warm What are the different types of dietary fat? The four main types of fat found in ...

158

Fats and oils  

International Nuclear Information System (INIS)

The glycerin ethers with higher fat acids are named fats. Fats with residua off-peak higher acids present oils which pick out from plants. Fats and oils usually contain residua of carboxylic acids C10-C18

159

Radiation initiated grafting  

International Nuclear Information System (INIS)

Various methods of grafting of vinyl monomers on to synthetic polymers have been presented with an emphasis for suppressing the parasitic homopolymerisation both in in-source grafting as well as post-irradiation grafting. The parameters like glass transition temperature of the polymer, preswelling, swelling along with grafting etc., have been considered in detail for obtaining the maximum graft yield with least homopolymerisation. Recent work carried out on grafting of vinyl monomers on to the synthetic fibres and films have been presented and discussed. Practical applications of radiation grafted materials are indicated. (author)

160

Grafting onto polyformaldehyde fibers  

International Nuclear Information System (INIS)

e chemical method was used during the grafting reaction. The AA- and AN-grafted PF fibers could be dyed in intense deep shades with cationic dyes. Similarly, AM-grafted substrates gave bright deep shades with acid dyes. Infrared studies, used to analyze the grafted PF fibers, indicated the presence of --COOH, --CN, and --NH2 groups introduced in the fiber structure as a result of grafting with AA, AN, and AM. 2 tables, 14 figures

 
 
 
 
161

Fat Analysis  

Science.gov (United States)

Lipids, proteins, and carbohydrates constitute the principal structural components of foods. Lipids are a group of substances that, in general, are soluble in ether, chloroform, or other organic solvents but are sparingly soluble in water. However, there exists no clear scientific definition of a lipid, primarily due to the water solubility of certain molecules that fall within one of the variable categories of food lipids (1). Some lipids, such as triacylglycerols, are very hydrophobic. Other lipids, such as di- and monoacylglycerols, have both hydrophobic and hydrophilic moieties in their molecules and are soluble in relatively polar solvents (2). Short-chain fatty acids such as C1-C4 are completely miscible in water and insoluble in nonpolar solvents (1). The most widely accepted definition is based on solubility as previously stated. While most macromolecules are characterized by common structural features, the designation of "lipid" being defined by solubility characteristics is unique to lipids (2). Lipids comprise a broad group of substances that have some common properties and compositional similarities (3). Triacylglycerols are fats and oils that represent the most prevalent category of the group of compounds known as lipids. The terms lipids, fats, and oils are often used interchangeably. The term "lipid" commonly refers to the broad, total collection of food molecules that meet the definition previously stated. Fats generally refer to those lipids that are solid at room temperature and oils generally refer to those lipids that are liquid at room temperature. While there may not be an exact scientific definition, the US Food and Drug Administration (FDA) has established a regulatory definition for nutrition labeling purposes. The FDA has defined total fat as the sum of fatty acids from C4 to C24, calculated as triglycerides. This definition provides a clear path for resolution of any nutrition labeling disputes.

Min, David B.; Ellefson, Wayne C.

162

Bone grafting: An overview  

Directory of Open Access Journals (Sweden)

Full Text Available Bone grafting is the process by which bone is transferred from a source (donor to site (recipient. Due to trauma from accidents by speedy vehicles, falling down from height or gunshot injury particularly in human being, acquired or developmental diseases like rickets, congenital defects like abnormal bone development, wearing out because of age and overuse; lead to bone loss and to replace the loss we need the bone grafting. Osteogenesis, osteoinduction, osteoconduction, mechanical supports are the four basic mechanisms of bone graft. Bone graft can be harvested from the iliac crest, proximal tibia, proximal humerus, proximal femur, ribs and sternum. An ideal bone graft material is biologically inert, source of osteogenic, act as a mechanical support, readily available, easily adaptable in terms of size, shape, length and replaced by the host bone. Except blood, bone is grafted with greater frequency. Bone graft indicated for variety of orthopedic abnormalities, comminuted fractures, delayed unions, non-unions, arthrodesis and osteomyelitis. Bone graft can be harvested from the iliac crest, proximal tibia, proximal humerus, proximal femur, ribs and sternum. By adopting different procedure of graft preservation its antigenicity can be minimized. The concept of bone banking for obtaining bone grafts and implants is very useful for clinical application. Absolute stability require for successful incorporation. Ideal bone graft must possess osteogenic, osteoinductive and osteocon-ductive properties. Cancellous bone graft is superior to cortical bone graft. Usually autologous cancellous bone graft are used as fresh grafts where as allografts are employed as an alloimplant. None of the available type of bone grafts possesses all these properties therefore, a single type of graft cannot be recomm-ended for all types of orthopedic abnormalities. Bone grafts and implants can be selected as per clinical problems, the equipments available and preference of the surgeon. A search for ideal bone graft is on and may continue till time to time. [Vet World 2010; 3(4.000: 198-200

D. O. Joshi

2010-08-01

163

Grafting and curing  

International Nuclear Information System (INIS)

Progress in radiation grafting and curing is briefly reviewed. The two processes are shown to be mechanistically related. The parameters influencing yields are examined particularly for grafting. For ionising radiation grafting systems (EB and gamma ray) these include solvents, substrate and monomer structure, dose and dose-rate, temperature and more recently role of additives. In addition, for UV grafting, the significance of photoinitiators is discussed. Current applications of radiation grafting and curing are outlined. The recent development of photoinitiator free grafting and curing is examined as well as the potential for the new excimer laser sources. The future application of both grafting and curing is considered, especially the significance of the occurrence of concurrent grafting during cure and its relevance in environmental considerations

164

Composite graft tympanoplasty  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Seventy six ears with chronic suppurative otitis media and fit for tympanoplasty were subjected to grafting with combination of perichondrium and cartilage (composite graft) for restoration of sound conducting apparatus and reconstruction of canal wall. A comparison with temporal fascia grafting has been done. Composite graft procedure gave better functional improvement, helped in reconstruction of canal wall and was also useful in elimination of retraction pockets.

Mukherjee, S.; Chamyal, P. C.

1997-01-01

165

Saturated fat (image)  

Science.gov (United States)

Saturated fat can raise blood cholesterol and can put you at risk for heart disease and stroke. You should ... limit any foods that are high in saturated fat. Sources of saturated fat include whole-milk dairy ...

166

Dietary fat and children  

Science.gov (United States)

Children and fat free diets; Fat free diet and children ... Some fat in the diet is needed for normal growth and development. However, many conditions such as obesity, heart disease, and diabetes are linked to ...

167

Grafting on polyester fibers  

International Nuclear Information System (INIS)

Acrylic acid (AA) and acrylonitrile (AN) were used to carry out grafting on polyester (PE) fibers using the techniques of initiation by ?-radiation as well as benzoyl peroxide. Extent of grafting depended upon the time, concentration of the initiator, and the monomer as well as on the irradiation dose. AA grafted fibers were rendered more hydrophilic than AN grafted fibers for equivalent amount of grafts. Considerable improvement in dyeability of the PE fibers was possible through grafting. About 50 percent to 100 percent improvement with disperse dyes was observed in case of PE fibers containing 22.4 percent and 9.0 percent graft of AA and AN, respectively. Intense fast dyeing with direct and basic (cationic) dyes was also possible, and the dye content was proportional to the extent of graft introduced in the fiber. The CN groups were reduced to NH2 groups in the AN graft on the fiber. With the increased amount of AA graft, the maxima in the zeta potential curve shifted toward higher acidic pH as greater amounts of alkali were utilized by the --COOH groups in the graft. In this respect, CN groups were less sensitive due to their lesser polarity as compared to the carboxylic groups. Surface charge density (S.C.D.) studies showed that the effective surface area of the fiber decreased with the increase in the amount of graft. Surface conductivity (S.C.) studies revealed that with increase in the number of polar groups (--COOH) on the surface of the fiber, th (--COOH) on the surface of the fiber, the S.C. increased with the increase in the amount of AA graft. In case of AN grafts, the reduction in effective surface area of the fiber played a more important role than the contribution by the CN groups to surface conductivity. (U.S.)

168

Thoracic stent-graft  

Directory of Open Access Journals (Sweden)

Full Text Available The stent-graft is a device constructed from a stent and vascular graft and is inserted by means of an interventional procedure under imaging guidance. In 1986, Balko et al.1 reported the first stentgraft experiment, in which a Z stent covered with polyurethane was inserted into an animal aorta. In the early 1990s, Parodi et al.2 reported clinical introduction of the stent-graft for abdominal aortic aneurysm. In comparison to the abdominal aortic stent-graft, the thoracic stent-graft has several disadvantages, including difficulties associated with the aortic arch curvature and the relatively large caliber of the stent-graft, and the risk of central nervous system or spinal complication. However, the thoracic stentgraft is advantageous because of minimal procedural invasiveness in comparison to surgical graft replacement. In 1994, Dake et al.3 reported transluminal placement of an endovascular stent-graft for thoracic aortic aneurysm, and Kato et al.4 reported use of a stent-graft for aortic dissection and suggested that the stent-graft could be considered an alternative to surgical treatment.

Hyodoh H.

2007-01-01

169

Fats and Your Child  

Science.gov (United States)

... methods allow the fat to drip away during cooking, which cuts down on calories, too. Frying, on the other hand, adds fat. Remove skin from poultry. Beware of reduced-fat and low-fat claims. These products often have more sugar added and just as many calories. Pack school ...

170

Learning about Fats  

Science.gov (United States)

... 230 calories from fat) Two tablespoons of peanut butter = 75% fat (140 of 190 calories from fat) One tablespoon ... in meat and other animal products, such as butter, cheese, and all milk except skim. Saturated fats are also in palm and coconut oils, which ...

171

The safety of autologous fat transfer in breast cancer: Lessons from stem cell biology  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Autologous fat grafting is versatile tool in plastic surgery and is increasing used for reconstruction following breast conserving surgery for breast cancer. Part of the reconstructive qualities of the transferred fat may be due to the presence of adipose derived mesenchymal stem cells (ADMSC) playing an angiogenic and an adipogenic role. In this context it must be considered if autologously engrafted fat tissue could contribute to carcinogenesis following breast conserving surgery. In this a...

Pearl, Ra; Pacifico, Md; Leedham, Sj

2012-01-01

172

Axillobifemoral bypass grafting  

Digital Repository Infrastructure Vision for European Research (DRIVER)

INTRODUCTION Axillo-femoral bypass (AxF) means connecting the axillar and femoral artery with the graft that is placed subcutaneously [1]. Usually, this graft is connected with contralateral femoral artery via one accessory subcutaneous graft, and this connection is known as axillobifemoral bypass (AxFF). This extra-anatomic procedure is an alternative method to the standard reconstruction of aortoiliac region when there are contraindications for general or local reasons. OBJECTIVE The object...

Davidovi? Lazar B.; Mitri? Milan S.; Kosti? Dušan M.; Maksimovi? Živan V.; Cvetkovi? Slobodan D.; ?inara Ilijas S.; Dimi? Andreja D.; Ili? Nikola S.

2004-01-01

173

Body Fat Measurement Tools  

Science.gov (United States)

... Cyberkitchen Fitness Center Shape Up & Drop 10 Body Fat Lab BMI Calculator Pregnancy Weight Gain Children Assessing ... Contact List Request for Support Measurement Tools Body fat has many important functions. It is: a "storage ...

174

Trans Fats and Memory  

Medline Plus

Full Text Available ... Related MedlinePlus Pages Dietary Fats Memory Transcript Eating foods that are high in trans fats may not ... can be found in baked goods, margarine, snack foods, fast foods, microwave popcorn, coffee creamer and more. ...

175

Trans Fats and Memory  

Medline Plus

Full Text Available ... 2014 Related MedlinePlus Pages Dietary Fats Memory Transcript Eating foods that are high in trans fats may ... notably worse performance” on the memory test. Participants eating the highest amounts recalled about 11 fewer words ...

176

Toxicity of abdominal fat  

Directory of Open Access Journals (Sweden)

Full Text Available Abdominal fat or truncal obesity consists of both subcutaneous and visceral fat. It has been found that visceral fat is more metabolically active than subcutaneous fat. The low-level inflammation linked with abdominal fat is associated with insulin resistance and with increases in the release of inflammatory adipokines and cytokines. As a result of these changes, abdominal fat can cause a variety of health conditions. In this review, we focus on the adverse effects of abdominal fat on the body and how it can lead to the development of cardiovascular disease, hypertension, type 2 diabetes mellitus, hyperlipidemia, stroke and cancer. Additionally, we discuss how abdominal fat can be reduced as a result from correction of hormonal deficiencies.

Shawn Mathew

2013-08-01

177

Trans Fats and Memory  

Medline Plus

Full Text Available ... lower right-hand corner of the player. Trans Fats and Memory HealthDay November 19, 2014 Related MedlinePlus Pages Dietary Fats Memory Transcript Eating foods that are high in ...

178

What Are the Types of Fat?  

Science.gov (United States)

... move.va.gov What Are the Types of Fat? Most foods contain several different kinds of fat. ... harmful dietary fats. The four major types of fats are: • Monounsaturated fats • Polyunsaturated fats • Saturated fats • Trans ...

179

Coronary Artery Bypass Graft  

Medline Plus

Full Text Available ... the chest wall or arteries from the arm (radial artery) are then used to bypass the clogged ... final location using the same chest incision. The radial artery may also be used as a graft. ...

180

Coronary Artery Bypass Graft  

Medline Plus

Full Text Available ... lower your blood cholesterol can help slow the process that clogs arteries. Exercise and losing weight, under ... the clogged arteries. Coronary Artery Bypass Graft This process of taking blood vessels from one part of ...

 
 
 
 
181

Axillobifemoral bypass grafting  

Directory of Open Access Journals (Sweden)

Full Text Available INTRODUCTION Axillo-femoral bypass (AxF means connecting the axillar and femoral artery with the graft that is placed subcutaneously [1]. Usually, this graft is connected with contralateral femoral artery via one accessory subcutaneous graft, and this connection is known as axillobifemoral bypass (AxFF. This extra-anatomic procedure is an alternative method to the standard reconstruction of aortoiliac region when there are contraindications for general or local reasons. OBJECTIVE The objective of this paper is to show early and late results of AxFF bypass grafting as well as to show the indications for AxFF bypass. METHODS The sample consisted of 37 patients. The procedure was performed in 28 patients who suffered from aortoiliac occlusive disease and who were at high risk due to the comorbidity- in one patient with the rupture of juxtarenal aneurysm of abdominal aorta; in five patients with aortoenteric fistula, in two patients with iatrogenic lesion of abdominal aorta and in one female patient with anus preternaturalis definitivus who was treated for rectovaginal fistula. Donor's right axillary artery was used in 26 cases (70.3%, and donor's left axillary artery was used in 9 cases (29.7%. Dacron graft was used in 34 patients and Polytetrafluo-roethlylene graft was used in three patients. Simultaneously, profundo-plastic was done in four patients and femoro-popliteal bypass was performed in three patients. In five patients who suffered from aortoenteric fistula, simultaneous intervention of gastrointerstinal system has been done, x2 test was used for statistical evaluation and life table method was used for verification of late graft patency. RESULTS The rate of early postoperative mortality was 13.5%. The causes of death were: sepsis -1, MOFS - 3, and infarct myocardium -1. The mean follow up period was 40.1 months, ranging from six months to 17 years. During the follow up period, an early graft thrombosis was identified in two and late graft occlusion was reported in four patients. As the cause of occlusion, the progression of occlusive disease of receptive artery was identified in three patients, while anastomotic neointimae hyperplasia of recipient artery was identified in one patient. Three patients died during the follow up period. As the cause of death, CVI was reported in two patients and malignancy of the urinary tract was fpund in one patient. The other complications were - artery angulation on the level of proximal anastomosis in one patient (Figure 1, false aneurysm in one patient, perigraft seroma in one patient and graft infection in three patients. Life table method has shown that cumulative rate of late graft patency is 80.39% after five years (Graph 1. DISCUSSION Our results were analyzed and compared with the results of the study on 283 patients who had undergone aortobifemoral bypass (AFF operation due to the aortoiliac occlusive disease. This study was completed in 1995 (18. The results showed that there was no statistically significant differences between AxFF and AFF group (p>0.05, considering early mortality rate and late graft patency (Graph 2. The review of mortality and late patency rate after AxFF bypass grafting in a world well known studies has shown the similar results (Table 1. CONCLUSION The authors suggest that axilobifemoral bypass is indicated when there are contraindications or difficulties to perform anatomic reconstruction due to the abdomen condition (infection, adhesion, comorbidity as well as in high risk patients with low life expectancy.

Davidovi? Lazar B.

2004-01-01

182

Perbandingan Keberhasilan Miringoplasti Mediolateral Dengan Medial dan Lateral  

Directory of Open Access Journals (Sweden)

Full Text Available Myringoplasty is a reconstructive procedure to repair timpanic membrane perforation, with mobile ossicular chain, and no pathological tissue in the middle ear cavity. In myringoplasty using lateral graft, the failure are tympanic membrane lateralization and anterior sulcus blunting. In medial graft, the failure is reperforation of the anterior tympanic membrane. Using mediolateral graft technique, as a hybrid from medial and lateral technique, could decrease the failure of the myringoplasty. The objective is to compare mediolateral graft myringoplasty with medial and lateral graft in anterior and subtotal perforation. Methode: A clinical trial and parallel design with three treatments which perform in Eye–ENT Private Clinic in Bandung from January-November 2006. Evaluation was done to see the successful of myringoplasty in anterior and subtotal perforation using transcanal approach with local anesthesia. We observed the result of myringoplasty with mediolateral graft compare with medial and lateral graft that will be achieved if the graft grow completely and increasing of conductive hearing ability _10 db. Result: Of the ninety-nine subject, the successful rate of myringoplasty using mediolateral graft was 100%, medial graft 90.3% and lateral graft 81.8%. Conclusion: Mediolateral technique as good as medial technique but still better than lateral technique.

Shinta Fitri Boesoirie

2009-12-01

183

Radiation grafted adhesive primers  

International Nuclear Information System (INIS)

Electron-beam and UV radiation can induce covalent attachment of unsaturated monomers onto a variety of polymer surfaces. The surface characteristics of a polymeric material can therefore be precisely manipulated by grafting the proper combination of monomers onto the surface. Radiation-grafted, sterically nonhindered tertiary acrylamides behave surprisingly well as primers for acidic pressure-sensitive adhesives. Physical and spectroscopic analyses of grafted acrylamides indicate that this unusual behavior is due to hydrogen bonding between the amide functionality in the primer and the acid functionality in the adhesive. Primary and secondary acrylamides are postulated to be less effective because they have the tendency to form hydrogen bonded dimers within the primer rather than interacting with the adhesive. (author)

184

Fat Emulsions for Injection  

Science.gov (United States)

Your doctor has ordered fat emulsion to be used as a source of calories and fatty acids to maintain or increase your weight. The medication ... Before you administer fat emulsion, look at the solution closely. It should be free of floating material. Gently squeeze the bag or observe ...

185

Know Your Fats  

Science.gov (United States)

... options, including butter, might be a better choice. Butter has a high amount of saturated fat and some trans fat, whereas many hard margarines ... partially hydrogenated or hydrogenated vegetable oils or saturated ... a substitute for butter, and choose soft margarines (liquid or tub varieties) ...

186

Trans Fats and Memory  

Medline Plus

Full Text Available ... right-hand corner of the player. Trans Fats and Memory HealthDay November 19, 2014 Related MedlinePlus Pages ... linked trans fats to worse memory in young and middle-aged men. The researchers included about 1, ...

187

Coronary Artery Bypass Graft  

Medline Plus

Full Text Available ... needed to prevent a heart attack or other heart problems. A CABG surgery includes taking blood vessels from other parts of ... inform your doctor in case you feel your heart is beating quickly, slowly, or skipping ... artery bypass graft surgery is relatively safe. Risks and complications are rare ...

188

[Intraabdominal fat necrosis].  

Science.gov (United States)

The processes that course with intraabdominal fat necrosis often manifest with acute or subacute abdominal pain; these clinical findings can be caused by various conditions, including epiploic appendagitis, omental infarction, encapsulated fat necrosis, mesenteric panniculitis, appendicitis, diverticulitis, and certain neoplasms. In this context, although the anatomic location of the pain and accompanying symptomatology can help orient the diagnosis, there is a risk of unnecessary surgery. Imaging tests like ultrasonography and especially computed tomography are essential for diagnosing intraabdominal fat necrosis. Radiologists must be familiar with the characteristic findings for all the conditions that can cause acute or subacute abdominal pain to ensure appropriate management and prevent unnecessary surgery. PMID:22019421

Aguilar-García, J J; Alcaide-León, P; Vargas-Serrano, B

2012-01-01

189

The repair of critical-sized bone defects using expedited, autologous BMP-2 gene-activated fat implants.  

Science.gov (United States)

The repair of bone defects can be induced experimentally with bone morphogenetic protein-2 (BMP-2) producing fat-derived stem cells, but this ex vivo tissue engineering method requires the isolation and long-term culture of autologous cells. To develop an expedited bone repair strategy, we transferred BMP-2 cDNA directly to autologous fat tissue fragments that were held in culture for only 24 h before implantation. We evaluated the ability of such gene-activated fat grafts to regenerate large segmental bone defects in rats. Fat tissue was harvested from 2 of 35 male Fischer 344 rats used for this study. The fat tissue fragments were incubated with an adenoviral vector carrying the cDNA encoding either BMP-2 or green florescent protein (GFP), or they remained unmodified. According to their group, the segmental femoral bone defects of 33 rats were filled press fit with either BMP-2-activated fat tissue, GFP-transduced fat tissue, or unmodified fat tissue. Another control group remained untreated. Femora were evaluated by radiographs, microcomputed tomography, biomechanical torsional testing, and histology. Radiographically and histologically, 100% of the femora treated with BMP-2-activated fat grafts were bridged at 6 weeks after surgery. The femora of this group exceeded the bone volume and the biomechanical stability of intact, contralateral femora. Control defects receiving no treatment, unmodified fat tissue, or GFP-transduced fat were filled with fibrous or adipose tissue, as evaluated by histology. The use of BMP-2 gene-activated fat tissue grafts represents an expedited and effective bone repair strategy that does not require the extraction and expansion of stem cells. PMID:20035609

Betz, Oliver B; Betz, Volker M; Abdulazim, Ahmed; Penzkofer, Rainer; Schmitt, Bärbel; Schröder, Christian; Mayer-Wagner, Susanne; Augat, Peter; Jansson, Volkmar; Müller, Peter E

2010-03-01

190

The Influence of Dietary Fat on Liver Fat Accumulation  

Science.gov (United States)

Obesity is a known risk factor for the development of non-alcoholic fatty liver disease (NAFLD); however, it has been suggested that dietary fat, both amount and composition, may play a pivotal role in its development, independent of body fatness. Studies that have investigated the role of dietary fat on liver fat accumulation are reasonably sparse. We review here the available work that has investigated the impact of dietary fat: amount, composition and frequency, on liver fat accumulation in human observational and intervention studies. Overall, it would seem that total calorie consumption, rather than dietary fat composition, is an important factor in the development of fatty liver disease in humans. PMID:25389901

Green, Charlotte J.; Hodson, Leanne

2014-01-01

191

Trans Fats and Memory  

Medline Plus

Full Text Available ... are no longer Generally Recognized as Safe in human food. Many companies have phased out trans fats ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated ...

192

Facts about polyunsaturated fats  

Science.gov (United States)

... amounts of polyunsaturated fats include: Walnuts Sunflower seeds Flax seeds or flax oil Fish, such as salmon, mackerel, ... 2 meals with fish per week. Sprinkle ground flax seed on your meal. Add walnuts or sunflower seeds ...

193

Weighing in on Dietary Fats  

Science.gov (United States)

... be solid at room temperature. Solid fats include butter, meat fats, stick margarine, shortening, and coconut and palm oils. ... Look for recipes that use applesauce instead of butter or oil. Instead of making ... for dessert. Use fat-free or low-fat dairy products when possible. ...

194

Dacron graft aneurysm treated by endovascular stent-graft  

International Nuclear Information System (INIS)

A 72-year old man who underwent aorto-bifemoral bypass with insertion of a Dacron graft 18 years previously presented with an aneurysm in the left limb of his graft. Angiography also demonstrated a bilateral occlusion of the popliteal arteries. Computed tomography (CT) angiography was performed and showed a localized dilation of 3 cm in the left limb of the graft, which had a diameter of 14 mm throughout. In view of the technical difficulties of a surgical procedure, an endovascular stent was considered. Through a left femoral arteriotomy. a stent graft was inserted and deployed in the left limb of the graft. This resulted in total exclusion of the Dacron graft aneurysm. To the best of our knowledge, this is the first report of such a procedure.

195

Dacron Graft Aneurysm Treated by Endovascular Stent-Graft  

International Nuclear Information System (INIS)

A 72-year old man who underwent aorto-bifemoral bypass with insertion of a Dacron graft 18 years previously presented with an aneurysm in the left limb of his graft. Angiography also demonstrated a bilateral occlusion of the popliteal arteries. Computed tomography (CT) angiography was performed and showed a localized dilation of 3 cm in the left limb of the graft, which had a diameter of 14 mm throughout. In view of the technical difficulties of a surgical procedure, an endovascular stent was considered. Through a left femoral arteriotomy, a stent graft was inserted and deployed in the left limb of the graft. This resulted in total exclusion of the Dacron graft aneurysm. To the best of our knowledge, this is the first report of such a procedure

196

Siloxane-grafted membranes  

Science.gov (United States)

Composite cellulosic semipermeable membranes are disclosed which are the covalently bonded reaction product of an asymmetric cellulosic semipermeable membrane and a polysiloxane containing reactive functional group. The two reactants chemically bond by ether, ester, amide or acrylate linkages to form a siloxane-grafted cellulosic membrane having superior selectivity and flux stability. Selectivity may be enhanced by wetting the surface with a swelling agent such as water.

Friesen, D.T.; Obligin, A.S.

1989-10-31

197

Polystyrene modified by grafting  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese Diversos tipos de poliestireno modificados foram obtidos através da polimerização por enxertia (graft polymerization) de estireno na presença dos seguintes modificadores: copolímero de etileno-acetato de vinila (EVA); polietileno de baixa densidade (PE) e polibutadieno (PB). Os modificadores foram u [...] tilizados em separado e combinados. Em todos os casos, manteve-se a concentração de modificador fixa em 8% em peso e foram avaliadas as propriedades dos produtos obtidos em função da sua composição. A técnica de polimerização empregada foi a de massa/suspensão. Os melhores resultados foram obtidos para os sistemas PS/modificadores mistos. Os resultados obtidos para estes sistemas comprovam que a copolimerização por enxertia gera produtos com melhores propriedades de impacto do que as obtidas, a partir de misturas mecânicas dos componentes individuais, em sistemas semelhantes. Abstract in english Several grades of modified polystyrene were obtained through the graft polymerization of styrene in the presence of modifiers such as ethylene-vinyl acetate (EVA), low density polyethylene (PE), and polybutadiene (PB). These modifiers were used by themselves and in combination. In all cases, the mod [...] ifier concentration was kept constant at 8% w/w, and the product properties were determined as a function of composition. The polymerization technique employed was that of mass/suspension. The best results were obtained for the PS/mixed modifiers systems. The results confirm that graft copolymers present better impact properties than those of mechanical blends of similar composition.

Avani Maria C, Rocha; Laura Hecker de, Carvalho; Antonio Gouveia de, Souza.

198

Using skeletonised grafts for coronary artery bypass grafting.  

Science.gov (United States)

Coronary artery bypass graft surgery relieves angina symptoms and reduces mortality among ischaemic heart disease patients. It remains the gold standard for the treatment of multi-vessel and left main coronary artery disease. It is a well-known fact that internal mammary artery conduits have excellent and long-lasting patency when used for coronary artery bypass grafting. Its supremacy is largely because it prevents atherosclerosis. The old-style internal mammary artery bypass grafting, classically known as pedicle grafting, includes a circular rim of tissue around the graft. Bilateral pedicled internal mammary arteries, especially among diabetic patients, have been reported to cause complications in the sternum like sternal osteomyelitis. In many studies it has been reported that dissection of pedicled internal mammary artery can lead to sternal devascularisation which can lead to higher incidence of infections. Considering the higher incidence of deep sternal infections in patients with double pedicled arterial grafts, dissection of internal mammary artery in skeletonised manner was proposed. In this review, we outline the advantages of skeletonised grafting with respect to incidence of sternal infection, patency rates, blood flow, post-coronary artery bypass graft pain and the length of the graft. PMID:25272561

Bawany, Faizan Imran; Khan, Muhammad Shahzeb; Khan, Asadullah; Kazi, Abdul Nafey; Naeem, Muhammed

2014-05-01

199

Preparation of anionic fibrous catalyst by radiation graft polymerization for biodiesel synthesis  

International Nuclear Information System (INIS)

Anionic fibrous catalyst for biodiesel production from vegetable oils and animal fats was synthesized through radiation induced graft polymerization of 4-chloromethylstyrene (CMS) onto a nonwoven polyethylene (NWPE) fabric followed by amination with trimethylamine (TMA). The influence of grafting degree of the TMA-CMS-g-NWPE at 0.25 M TMA concentration was investigated by elemental analyzer, FTIR and TGA. Results show that the density of trimethylammonium group increased with the degree of grafting. However, thermal properties of the TMA-CMS-g-NWPE reduced with the degree of grafting. The preliminary transesterification test on triolein/ethanol/decane solution using selected TMA-CMS-g-NWPE containing 3.01 mmol/g trimethylammonium found that 98% the triolein can be converted into biodiesel within 4 h reaction. High conversion of rapeseed oil into biodiesel provides more information on the capability of TMA-CMS-g-NWPE as ion exchanger for biodiesel production. (Author)

200

Axonal regeneration through arterial grafts.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The left common peroneal nerves of adult inbred mice were severed and allowed to regenerate through the lumina of Y-shaped tubes comprising grafts of abdominal aorta and its bifurcation. Very little regeneration took place within the grafts unless the distal nerve stump was inserted into one limb of the Y-tube. Using syngeneic grafts virtually all the axons regenerating through the lumen grew down the limb of the Y-tube containing the distal nerve. Using non-syngeneic grafts, however, a subst...

Anderson, P. N.; Turmaine, M.

1986-01-01

 
 
 
 
201

Fat scoring: Sources of variability  

Science.gov (United States)

Fat scoring is a widely used nondestructive method of assessing total body fat in birds. This method has not been rigorously investigated. We investigated inter- and intraobserver variability in scoring as well as the predictive ability of fat scoring using five species of passerines. Between-observer variation in scoring was variable and great at times. Observers did not consistently score species higher or lower relative to other observers nor did they always score birds with more total body fat higher. We found that within-observer variation was acceptable but was dependent on the species being scored. The precision of fat scoring was species-specific and for most species, fat scores accounted for less than 50% of the variation in true total body fat. Overall, we would describe fat scoring as a fairly precise method of indexing total body fat but with limited reliability among observers.

Krementz, D.G.; Pendleton, G.W.

1990-01-01

202

Pakistan. Graft-Polymerization Under Irradiation and its Effect on Water Repellency and Resistance to Certain Micro-Organisms  

International Nuclear Information System (INIS)

The fibre from the jute plants Corchorus capsularis and C. olitorius consists of cellulose (69-78%), lignin (10-15%), furfuraldehyde (9-11%), xylen (10-12%) and fat (1%). Jute fibre is commercially used for making sacks for packing purposes and is an important item of Pakistan's foreign trade. It was intended to graft-copolymerize jute with various monomers with the idea of determining its water absorption and resistance to microorganisms. Such studies would enlarge the scope of the commercial utilization of jute fibre. Graft-copolymerization or graft-polymerization in our studies invariably refers to soaking jute with monomers under the conditions of the experiment

203

Fat heaps : Source code  

DEFF Research Database (Denmark)

This report is an electronic appendix to our paper \\Fat heaps without regular counters". In that paper we described a new variant of fat heaps that is conceptually simpler and easier to implement than the original version. We also compared the practical performance of this data structure to that of other related data structures (run-relaxed weak queues and Fibonacci heaps). This report to- gether with an accompanying tar le gives the source code used in the experiments reported in the paper. By making the programs publicly available, we provide other researchers the opportunity to scrutinize the code and compare their own imple- mentations against ours.

Elmasry, Amr Ahmed Abd Elmoneim; Katajainen, Jyrki

2011-01-01

204

Human microvessel endothelial cell isolation and vascular graft sodding in the operating room.  

Science.gov (United States)

We have evaluated multiple factors inherent to an operating room-compatible endothelial cell procurement and sodding procedure. Microvessel endothelial cell isolations have been performed on fat tissue obtained from over 140 patients with a 100% success rate. Liposuction-derived fat was optimal with respect to cell yield, and isolation time. The devices and equipment used were acceptable to the operating room and the complete cell procurement procedure was successful even in the hands of personnel with minimal training. Fat digestion was achieved using crude clostridial collagenase, with an average cell yield of 1 x 10(6) microvessel endothelial cells/gm of fat. Evaluation of this procedure with canine fat using an operating room acceptable procedure resulted in a 100% procurement success rate requiring 1.5 hours (+/- .5 hrs) for completion of the fat isolation, and cell isolation procedure. Microvessel EC could subsequently be used in graft seeding or sodding techniques to establish endothelial cell monolayers on vascular grafts. Our results indicate that one person with minimal cell isolation background can reproducibly isolate large quantities of sterile autologous endothelial cells in the operating room for immediate use in endothelial cell seeding/sodding procedures. PMID:2765356

Williams, S K; Jarrell, B E; Rose, D G; Pontell, J; Kapelan, B A; Park, P K; Carter, T L

1989-04-01

205

Trans Fat Now Listed With Saturated Fat and Cholesterol  

Science.gov (United States)

... based foods. Essentially, trans fat is made when hydrogen is added to vegetable oil -- a process called ... of your food when eating or ordering out. Watch Calories. Don't be fooled! Fats are high ...

206

Polyether/Polyester Graft Copolymers  

Science.gov (United States)

Higher solvent resistance achieved along with lower melting temperature. New technique provides method of preparing copolymers with polypivalolactone segments grafted onto poly (2,6-dimethyl-phenylene oxide) backbone. Process makes strong materials with improved solvent resistance and crystalline, thermally-reversible crosslinks. Resulting graft copolymers easier to fabricate into useful articles, including thin films, sheets, fibers, foams, laminates, and moldings.

Bell, Vernon L., Jr.; Wakelyn, N.; Stoakley, D. M.; Proctor, K. M.

1986-01-01

207

Traumatic fat embolism syndrome.  

Directory of Open Access Journals (Sweden)

Traumatic fat embolism syndrome occurs most often following fractures of long bones sustained in road traffic accidents and is a common cause of medical consultation from the orthopedic surgery department. The sub-clinical presentation is subtle and expresses itself by the presence of hypoxemia, while the full clinical syndrome compromises respiratory insufficiency, an altered consciousness and a characteristic petechial rash. Recognition is simple once the patient is viewed in the context of his or her clinical setting. Diagnosis is aided further by the presence of hematological and biochemical abnormalities including anemia, thrombocytopenia, an elevated erythrocyte sedimentation rate and fat macroglobulinemia. Imaging by chest radiograph, computed tomography or magnetic resonance of the brain is used to confirm the extent of the respective organ involvement and to exclude alternative pathologies. The release of free fatty acids into the circulation and their subsequent effects is the key pathological event. Treatment is based on supportive care and high-dose corticosteroid therapy. We report a patient with traumatic fat embolism syndrome who developed the syndromes classical symptoms and signs following fracture of the long bones of his left lower leg. Admission to an intensive care unit, mechanical ventilatory support with positive end-expiratory pressure and corticosteroid therapy lead to his improvement and allowed eventual open reduction and internal fixation and discharge of our patient. Modern therapy offers a relatively good prognosis for patients with traumatic fat embolism syndrome; the optimal dose and timing of corticosteroid therapy in prophylaxis and treatment however, remain the subject of intense debate.

Tarig S. Al-Khuwaitir

2002-12-01

208

That Fat Cat  

Science.gov (United States)

This activity began with a picture book, Nurit Karlin's "Fat Cat On a Mat" (HarperCollins; 1998). The author and her students started their project with a 5-inch circular template for the head of their cats. They reviewed shapes as they drew the head and then added the ears and nose, which were triangles. Details to the face were added when…

Lambert, Phyllis Gilchrist

2012-01-01

209

Weight Gain and Saturated Fats  

Medline Plus

Full Text Available ... corner of the player. Weight Gain and Saturated Fats HealthDay October 16, 2014 Related MedlinePlus Pages Cholesterol Dietary Fats Weight Control Transcript Short-term weight gain is ...

210

Big, Fat World of Lipids  

Science.gov (United States)

... Articles | Inside Life Science Home Page The Big, Fat World of Lipids By Emily Carlson Posted August ... the doctor typically provides your levels of three fats found in the blood: LDL, HDL and triglycerides. ...

211

Weight Gain and Saturated Fats  

Science.gov (United States)

... the lower right-hand corner of the player. Weight Gain and Saturated Fats HealthDay October 16, 2014 Related MedlinePlus Pages Cholesterol Dietary Fats Weight Control Transcript Short-term weight gain is something ...

212

Lipid-based fat substitutes.  

Science.gov (United States)

Fats and oils account for 38% of the total calories in the diet of Western populations, especially in the U.S. They provide the most concentrated source of energy, 9 kcal/g of a triacylglycerol molecule compared with 4 kcal/g provided by carbohydrate and protein. In response to consumer demands for low-calorie or calorie-free fats and their reluctance to give up the taste of fat, current research efforts have been directed toward the development of lipid-like fat substitutes. These fat substitutes contain the fatty acids found in conventional fats and oils, with all the physical and organoleptic properties of fats, but provide few or no calories in the diet. Some of the fat substitutes are modified triacylglycerols (glycerol backbone) with reduced digestion and absorption; others are digestible and nondigestible carbohydrate fatty acid esters and polyesters, respectively. Sucrose polyester (Olestra), a sucrose molecule esterified with six to either fatty acids, is the most studied of the lipid-based fat substitutes containing a carbohydrate backbone. If approved by the FDA, sucrose polyester will find application in almost all fat-containing foods. Specialty fats or fat substitutes targeted to certain individuals with special needs are being developed. Among these are the medium-chain triacylglycerols and structured lipids (glycerol backbone), or ¿nutraceuticals¿ with reduced absorption and medical applications. Enzyme biotechnology is another tool available to lipid chemists to selectively modify, esterify, transform, transesterify, and interesterify fats and oils or synthesize new lipids such as structured lipids of food, nutritional, and medical importance. These designer fats may be the trend in the future to produce medical lipids that do not occur normally in nature. The different types of lipid-based fat substitutes are reviewed with respect to their synthesis, analysis, metabolism, potential applications/uses, and the future of fat substitutes. PMID:8573281

Akoh, C C

1995-09-01

213

Viability of cartilage grafts in various forms.  

Science.gov (United States)

The viability of cartilage grafts, in many forms, has been researched since the using of cartilage grafts in surgical procedures. Cryopreservation period and viability of cartilage grafts have remained unclear. This study was performed to investigate the durability, viability, and behavior of fresh or cryopreserved cartilage grafts when used as autografts or allografts in various forms.Six cartilage grafts (1 of each preparation type; 3 blocks and 3 diced) were prepared by wrapping with Surgicel or autogenous fascia, or they were left bare. After the graft preparation stage, the cartilage grafts were inserted into pockets prepared on the dorsum of each rabbit. Groups 1, 2, 3, and 4 (6 rabbits in each group) received autogenous fresh grafts, allogenous fresh grafts, autogenous cryopreserved grafts, and allogenous cryopreserved grafts, respectively. All cartilage grafts were implanted for 2 months.At the end of the second month, specimens were harvested and analyzed. The bare grafts provided the most viable specimens. There was no significant difference between the frozen or fresh and allograft or autograft groups with respect to viability and resorption ratios. The bare block graft, in all groups, survived significantly more than the other graft types.Allografts (homografts), similar autografts, did not create major problems, and they had excellent host tolerance and low antigenicity, especially when the perichondrium was removed. Viability and durability of the bare grafts (diced and block) were better than fascia or Surgicel-wrapped cartilage graft forms. PMID:21959409

Firat, Cemal; Gurlek, Ali; Aydin, Nasuhi Engin; Aydn, Nasuhi Engin

2011-09-01

214

Weight Gain and Saturated Fats  

Medline Plus

Full Text Available ... Fats HealthDay October 16, 2014 Related MedlinePlus Pages Cholesterol Dietary Fats Weight Control Transcript Short-term weight ... muffins with unsaturated fat had lower bad LDL cholesterol levels, total cholesterol/good HDL cholesterol ratios and ...

215

The Influence of Dietary Fat on Liver Fat Accumulation  

Directory of Open Access Journals (Sweden)

Full Text Available Obesity is a known risk factor for the development of non-alcoholic fatty liver disease (NAFLD; however, it has been suggested that dietary fat, both amount and composition, may play a pivotal role in its development, independent of body fatness. Studies that have investigated the role of dietary fat on liver fat accumulation are reasonably sparse. We review here the available work that has investigated the impact of dietary fat: amount, composition and frequency, on liver fat accumulation in human observational and intervention studies. Overall, it would seem that total calorie consumption, rather than dietary fat composition, is an important factor in the development of fatty liver disease in humans.

Charlotte J. Green

2014-11-01

216

Radiation grafting of hydroxyethyl methacrylate on low density polyethylene and electric capacity of grafting copolymer  

International Nuclear Information System (INIS)

Grafting polymerization of hydroxyethyl methacrylate on low density polyethylene film has been studied by direct method. An effect of radiation dose, dose rate, concentration of cupric ion and polar monomer on grafting rate of polyethylene has been discussed. The grafted product was characterized by infrared spectrum. It was found that the electric capacity of grafting copolymer increase with the increasing of grafting rate

217

Cerebral fat embolism  

International Nuclear Information System (INIS)

A case of cerebral fat embolism is reported. A 18-year-old patient with multiple bone fractures was in semiconma immediately after an injury. Brain CT showed no brain swelling or intracranial hematoma. Hypoxemia and alcoholemia were noted on admission, which returned to normal without improvement of consciousness level. In addition, respiratory symptoms with positive radiographic changes, tachycardia, pyrexia, sudden drop in hemoglobin level, and sudden thrombocytopenia developed. These symptoms were compatible with Gurd's criteria of systemic fat embolism. Eight days after injury, multiple low density areas appeared on CT and disappeared within the subsequent two weeks, and subdural effusion with cerebral atrophy developed. These CT findings were not considered due to cerebral trauma. Diagnosis of cerebral fat embolism was made. The subdural effusion was drained. Neurologic and pulmonary recoveries took place slowly and one month following the injury the patient became alert and exhibited fully coordinated limb movement. The CT scans of the present case well corresponded with hitherto reported pathological findings. Petechiae in the white matter must have developed on the day of injury, which could not be detected by CT examination. It is suggested that some petechial regions fused to purpuras and then gradually resolved when they were detected as multiple low density areas on CT. CT in the purpuras phase would have shown these lesions as high density areas. These lese lesions as high density areas. These lesions must have healed with formation of tiny scars and blood pigment which were demonstrated as the disappearance of multiple low density areas by CT examination. Cerebral atrophy and subsequent subdural effusion developed as a result of demyelination. The patient took the typical clinical course of cerebral fat embolism and serial CT scans served for its assessment. (author)

218

The trochanteric fat pad  

Directory of Open Access Journals (Sweden)

Full Text Available Technological developments based on the use of autologous white adipose tissue (WAT attracted attention to minor fat depots as possible sources of adipose tissue. In plastic surgery, the trochanteric fatty pad is one of the most used WAT depots for its location and organoleptic characteristics that make it particularly suitable for reconstructive procedures. Despite its wide use in clinic, the structure of this depot has never been studied in detail and it is not known if structural differences exist among trochanteric fat and other subcutaneous WAT depots. The present study was performed on trochanteric fat pad with the aim to clarify the morphology of its adipocytes, stroma and microcirculation, with particular reference to the stem niches. Histological and ultrastructural studies showed that the main peculiar feature of the trochanteric fat concerns its stromal component, which appears less dense than in the other subcutaneous WATs studied. The intra-parenchymal collagen stroma is poor and the extracellular compartment shows large spaces, filled with electron-light material, in which isolated collagen bundles are present. The adipocytes are wrapped in weak and easily detachable collagen baskets. These connective sheaths are very thin compared to the sheaths in other subcutaneous WAT depots. The capillaries are covered by large, long and thin elements surrounded by an external lamina; these perivascular cells are poor in organelles and mainly contain poly-ribosomes. In conclusion, when compared to other WAT deposits, the trochanteric fatty pad shows structural peculiarities in its stroma and microcirculation suggesting a high regenerative potential. Resistance, dissociability, microvascular weft and high regenerative potential make the trochanteric fatty pad a privileged source for harvesting in autologous WAT-based regenerative procedures.

A. Sbarbati

2011-04-01

219

Fat Replacers in Meat Products  

Directory of Open Access Journals (Sweden)

Full Text Available There is a great interest regarding demand for foods with health enhancing properties as low-fat meat products due to the human health and nutrition correlation. Various aspects of interest relating to product design and fat reducing strategy has been reported. These aspects concerning nutritional, sensory, technological, safety, appreciation, legal and cost procedures are important to a improved new product design. Due to their different texture properties, processing conditions and different quality evaluations used in the reformulated meat derivatives, the feasibility of low-fat meat products manufacturing has been investigated. In previous review paper, various factors such as consumer acceptability, technological, emerging strategies for the modification of meat fat level, fatty acid (FA composition, and non-meat ingredients or fat-replacers for the production were monitored for low-fat meat products and fat reduction concept.

Ozlem Tokusoglu

2003-01-01

220

Imaging of pulmonary fat  

International Nuclear Information System (INIS)

Full text: Respiratory complications are common after joint arthroplasty with fat emboli (FE) and thromboembolic disease (TED) being the most serious. FE are minute fat globules which can be demonstrated in circulation following trauma to long bones which contain a mixture of fat and bone marrow elements. Detection of FE in the lungs can distinguish it from other causes of hypoxia and be useful in directing appropriate treatment. An 82-year-old women with no history of TED presented with pleuritic chest pain following total knee arthroplasty. She had a high probability perfusion lung study in conjunction with a positive 99Tcm Phytate study of the lungs. The perfusion and 99Tcm Phytate pulmonary studies successfully identified the presence of FE and TED as the causes of respiratory distress. The patient commenced intravenous heparin and supportive respiratory therapy. A similar study performed two weeks later showed clearance of FE from the lungs and substantial but incomplete resolution of TED. Combined perfusion and 99Tcm Phytate imaging has been shown to be valuable addition for the diagnosis of FE as well as TED in lungs after arthroplasty. Following treatment with heparin, the patient developed bilateral adrenal haemorrhages, which were promptly diagnosed and treated. She was discharged in a well state. Copyright (2000) The Australian and New Zealand Society of Nuclear Medicine Inc

 
 
 
 
221

Saphenous vein graft vs. radial artery graft searching for the best second coronary artery bypass graft.  

Science.gov (United States)

Coronary artery bypass grafting (CABG) was first used in the late 1960s. This revolutionary procedure created hope among ischemic heart disease patients. Multiple conduits are used and the golden standard is the left internal mammary artery to the left anterior descending artery. Although all approaches were advocated by doctors, the use of saphenous vein grafts became the leading approach used by the majority of cardiac surgeons in the 1970s. The radial artery graft was introduced at the same time but was not as prevalent due to complications. It was reintroduced into clinical practice in 1989. The procedure was not well received initially but it has since shown superiority in patency as well as long-term survival after CABG. This review provides a summary of characteristics, technical features and patency rates of the radial artery graft in comparison with venous conduits. Current studies and research into radial artery grafts and saphenous vein grafts for CABG are explored. However, more studies are required to verify the various findings of the positive effects of coronary artery bypass grafting with the help of radial arteries on mortality and long-lasting patency. PMID:24198449

Al-Sabti, Hilal Ali; Al Kindi, Adil; Al-Rasadi, Khalid; Banerjee, Yajnavalka; Al-Hashmi, Khamis; Al-Hinai, Ali

2013-10-01

222

A Reappraisal of Saphenous Vein Grafting  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Autologous saphenous vein grafting has been broadly used as a bypass conduit, interposition graft, and patch graft in a variety of operations in cardiac, thoracic, neurovascular, general vascular, vascular access, and urology surgeries, since they are superior to prosthetic veins. Modified saphenous vein grafts (SVG), including spiral and cylindrical grafts, and vein cuffs or patches, are employed in vascular revascularization to satisfy the large size of the receipt vessels or to obtain a be...

Yuan Shi-Min; Jing Hua

2011-01-01

223

Interventions in infrainguinal bypass grafts.  

Science.gov (United States)

The interventional radiologist plays an important role in the detection and prevention of infrainguinal bypass failure. Early detection and evaluation of flow-limiting lesions effectively preserve graft (venous bypass and polyester or expanded polytetrafluoroethylene bypass) patency by identifying stenoses before occlusion occurs. Delay in treatment of the at-risk graft may result in graft failure and a reduced chance of successful revascularization. For this reason, surveillance protocols form an important part of follow-up after infrainguinal bypass surgery. As well as having an understanding of the application of imaging techniques including ultrasound, MR angiography, CT angiography and digital subtraction angiography, the interventional radiologist should have detailed knowledge of the minimally invasive therapeutic options. Percutaneous transluminal angioplasty (PTA), or alternatively cutting balloon angioplasty, is the interventional treatment of choice in prevention of graft failure and occlusion. Further alternatives include metallic stent placement, fibrinolysis, and mechanical thrombectomy. Primary assisted patency rates following PTA can be up to 65% at 5 years. When the endovascular approach is unsuccessful, these therapeutic options are complemented by surgical procedures including vein patch revision, jump grafting, or placement of a new graft. PMID:16284703

Müller-Hülsbeck, S; Order, B-M; Jahnke, T

2006-01-01

224

FAS grafted superhydrophobic ceramic membrane  

International Nuclear Information System (INIS)

The hydrophobic properties of ?-Al2O3 membrane have been obtained by grafting fluoroalkylsilane (FAS) on the surface of the membrane. The following grafting parameters were studied: the eroding time of the original membrane, the grafting time, the concentration of FAS solution and the multiplicity of grafting. Hydrophobicity of the membranes was characterized by contact angle (CA) measurement. The thermogravimetric analysis (TGA) was used to investigate the weight loss process (25-800 deg. C) of the fluoroalkylsilane grafted on Al2O3 powders under different grafting conditions. The morphologies of the membranes modified under different parameters were examined by field emission scanning electron microscopy (FE-SEM) and the surface roughness (Ra) was measured using white light interferometers. A needle-like structure was observed on the membrane surface after modification, which causes the change of Ra. On the results above, we speculated a model to describe the reaction between FAS and ?-Al2O3 membrane surface as well as the formed surface morphology.

225

Radiation grafting on natural films  

International Nuclear Information System (INIS)

Different methods of polymer grafting using gamma irradiation are reported in the present study for the preparation of newly functionalized biodegradable films, and some important properties related to their mechanical and barrier properties are described. Biodegradable films composed of zein and poly(vinyl alcohol) (PVA) were gamma-irradiated in presence of different ratios of acrylic acid (AAc) monomer for compatibilization purpose. Resulting grafted films (zein/PVA-g-AAc) had their puncture strength (PS=37–40 N mm?1) and puncture deformation (PD=6.5–9.8 mm) improved for 30% and 50% PVA in blend, with 5% AAc under 20 kGy. Methylcellulose (MC)-based films were irradiated in the presence of 2-hydroxyethyl methacrylate (HEMA) or silane, in order to determine the effect of monomer grafting on the mechanical properties of films. It was found that grafted films (MC-g-HEMA and MC-g-silane) using 35% monomer performed higher mechanical properties with PS values of 282–296 N mm?1 and PD of 5.0–5.5 mm under 10 kGy. Compatibilized polycaprolactone (PCL)/chitosan composites were developed via grafting silane in chitosan films. Resulting trilayer grafted composite film (PCL/chitosan-g-silane/PCL) presented superior tensile strength (TS=22 MPa) via possible improvement of interfacial adhesion (PCL/chitosan) when using 25% silane under 10 kGy. Finally, MC-based films containing crystalline nanocellulose (CNC) as a filling agent were prepared and irradiated in presence of trimethylolpropane trimethacrylate (TMPTMA) as a grafted plasticizer. Grafted films (MC-g-TMPTMA) presented superior mechanical properties with a TS of 47.9 MPa and a tensile modulus (TM) of 1792 MPa, possibly due to high yield formation of radicals to promote TMPTMA grafting during irradiation. The addition of CNC led to an additional improvement of the barrier properties, with a significant 25% reduction of water vapor permeability (WVP) of grafted films. - Highlights: • Irradiation of zein/PVA/acrylic acid improved the mechanical properties of films. • Irradiation of Methylcellulose/NCC/TMPTMA improved the barrier properties of films. • Irradiation of chitosane/Methylcellulose/HEMA/silane improved the strength of films

226

Tissue Engineering Applications to Vascular Bypass Graft Development: The Use of Adipose-Derived Stem Cells  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The burgeoning field of vascular tissue engineering holds promise for the creation of a practical and successful small-diameter arterial bypass graft. Many creative combinations of autologous cells and scaffolds exist along with an equally long list of microenvironmental cues used to create a functional arterial conduit. This review outlines our work using abdominal wall fat as a source of autologous stem cells for vascular tissue engineering, focusing specifically on this stem cell’s avail...

Dimuzio, Paul; Tulenko, Thomas

2007-01-01

227

[Fat substitutes in human diet].  

Science.gov (United States)

Fat consumption in developed countries has increased steadily during this century reaching values higher than 40% of the daily total calorie intake. This situation has resulted in a high prevalence of obesity, cardiovascular disease, diabetes and some types of cancer. The health agencies in these countries have made strong recommendations for the population to reduce dietary fat intake in order to reduce total fat intake to les than 30% of the total calories, with a maximum of 10% calories derived from saturated fats. The food industry has taken a very active role developing a number of low fat foods and opening a new area of products called fat substitutes in order to help the consumers reduce their fat consumption. One of these substitutes is a synthetic product obtained by reacting fatty acids from natural sources and sucrose. The product is a polyester of sucrose and has been named olestra. Olestra has been approved by the US Food and Drug Administration (FDA) to be used in snacks and fried chips. Due to its lipophilic nature olestra has a negative effect on the absorption of fat soluble vitamins and nutrients. However, this problem may be solved by supplementation of the nutrients affected. In addition, olestra may cause gastrointestinal effects such as abdominal cramping and stool softening. The Company that developed olestra claims to have solved this problem by modifying the composition of fatty acids of the product. Olestra is being marketed in the USA under the name of Olean. PMID:10488387

Yáñez, E; Biolley, E

1999-06-01

228

POST CORONARY ARTERY BYPASS GRAFT STUDY (CABG)  

Science.gov (United States)

Relative effectiveness of moderate versus more aggressive lipid lowering, and of low dose anticoagulation versus placebo, in delaying saphenous vein coronary bypass graft atherosclerosis and preventing occlusion of saphenous grafts of patients with saphenous vein coronary bypass ...

229

Reoperative coronary artery bypass grafting  

Directory of Open Access Journals (Sweden)

Full Text Available Reoperative coronary artery bypass grafting (redo CABGoperation is associated with a high rate of mortality up to11.4%. It has been estimated that 10-20% of patients withhistory of coronary artery bypass grafting (CABG operationneed redo CABG operation within 10 years. Due tohigh operation risk percutaneous coronary interventionshave emerged as the preferred treatment for the patientswith a history of CABG operation and presenting withacute coronary syndrome. Here, we reported percutaneouscoronary intervention in a patient needed redo CABGoperation. J Clin Exp Invest 2013; 4 (3: 380-382Key words: Acute coronary syndrome, redo CABG operation,percutaneous coronary intervention.

Hüseyin Katlandur

2013-09-01

230

[Radioindication of bone graft healing].  

Science.gov (United States)

To control the state of transplanted bone in different terms following the plastic procedure a radioisotope study by strontium-85 was performed in 29 patients. The results of scannography (in 31 cases) and radiometry (in 42 cases) were analysed. The determination of the character of strontium-85 distribution and the intensity of its accumulation in the operated extremity makes it possible to assess the graft condition and the intensity of osteogenesis a greater precision and earlier than does roentgenography. Radioisotope investigation conducted dynamically enable the prognostication of the course of the graft healing process. PMID:333749

Kuznetsova, L B; Pavlova, L P; Kondrat'ev, V G; Khmelev, O N

1977-01-01

231

Graft healing in anterior cruciate ligament reconstruction  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Abstract Successful anterior cruciate ligament reconstruction with a tendon graft necessitates solid healing of the tendon graft in the bone tunnel. Improvement of graft healing to bone is crucial for facilitating an early and aggressive rehabilitation and ensuring rapid return to pre-injury levels activity. Tendon graft healing in a bone tunnel requires bone ingrowth into the tendon. Indirect Sharpey fiber formation and direct fibrocartilage fixation confer different anchorage stre...

Chen Chih-Hwa

2009-01-01

232

New variant for whole pancreas grafting  

International Nuclear Information System (INIS)

A new variant for whole pancreas grafting is described in which a segment of the duodenum and the spleen is included in the graft. The graft is placed extraperitoneally as in kidney transplantation. The exocrine drainage is with side-to-side anastomosis between duodenum and bladder. The spleen is irradiated to prevent the occurrence of GVHD, as is reported in splenic transplantation

233

Improvement of polymer stability by radiation grafting  

International Nuclear Information System (INIS)

th respect to the consumption of monomer, the grafting yield being less than 0.5%. Surface grafting is an efficient photostabilization method since grafted stabilizer is chemically bound to a polymeric surface and in this way the problem of evaporation of blended stabilizers during the prolonged use of polymeric materials is eliminated. (author)

234

Radiation Induced Graft Copolymerization of Polyvinyl Alcohol  

International Nuclear Information System (INIS)

In order to improve the properties of polyvinyl alcohol films and fibres, the graft copolymerization of various vinyl monomers to polyvinyl alcohol films by gamma ray irradiation was investigated. When thin films of polyvinyl alcohol were irradiated in a large excess of styrene no graft copolymerization was observed. With films containing more than 5% water the grafting proceeded smoothly. The highest value of styrene grafted was about 1,000% at a dose of 7X106r. The presence of water in the monomer solution was found to increase considerably the amount of grafted monomer. Methyl methacrylate behaved similarly to styrene in the grafting to polyvinyl alcohol films, the presence of a certain amount of water being essential. The efficiency of the grafting of methyl methacrylate was generally larger than that of the grafting of styrene. The highest value of the grafted methyl methacrylate was 4,000% and obtained at a dose of 5 X 105 r. Some experiments were carried out with acrylonitrile and vinyl acetate but compared with styrene and methyl methacrylate the efficiencies of the grafting of these monomers were not so high. The degree of swelling of the graft copolymers of polyvinyl-alcohol-styrene or methyl methacrylate in organic solvents was measured at 30oC. The relation between the degree of swelling and the percentage of monomer grafted was given by (degree of swelling %) = k (monomer grafted %)n. For polymers grafted with styrene n = 1, but for those grafted with methyl methacrylate n < 1. n and k have characteristic values which depend on the solvents used. (author)

235

Markers of primary graft dysfunction  

DEFF Research Database (Denmark)

The present invention relates to methods for diagnosing transplant rejection, or a condition associated with transplant rejection, such as, primary graft dysfunction in a subject, to antigen probe arrays for performing such a diagnosis, and to antigen probe sets for generating such arrays.

Hagedorn, Peter Technical University of Denmark,

236

Endovascular stent grafting: a review  

Energy Technology Data Exchange (ETDEWEB)

Endovascular stent grafts are intravascular devices composed of surgical graft material and a metallic frame, (Fig. 1). Their main application has been to treat aneurysms, but they have been used in vascular trauma and are being investigated for use in occlusive disease. Their advantage in treating aneurysms over conventional surgical treatment is that they are loaded into relatively small delivery systems (Fig. 2) and can be introduced to the area of interest from a remote site - usually the femoral artery. This avoids the morbidity of surgical exposure in difficult sites, such as the thoracic aorta, and lessens the cardiovascular stress to patients by eliminating the need to surgically cross-clamp the vessel being treated. The first description of abdominal aortic aneurysm exclusion by an endovascular stent graft was provided by Parodi and colleagues in 1991. Much of the early clinical experience in endovascular stent grafting was obtained from centres in Australia and Europe, and they are now reporting midterm follow-up data. There are now many centres in Canada and the United States involved in endovascular research and practice. (author)

Kribs, S. [Univ. of Western Ontario, Dept. of Vascular and Interventional Radiology, London, Ontario (Canada)

2001-06-01

237

Polyether-polyester graft copolymer  

Science.gov (United States)

Described is a polyether graft polymer having improved solvent resistance and crystalline thermally reversible crosslinks. The copolymer is prepared by a novel process of anionic copolymerization. These polymers exhibit good solvent resistance and are well suited for aircraft parts. Previous aromatic polyethers, also known as polyphenylene oxides, have certain deficiencies which detract from their usefulness. These commercial polymers are often soluble in common solvents including the halocarbon and aromatic hydrocarbon types of paint thinners and removers. This limitation prevents the use of these polyethers in structural articles requiring frequent painting. In addition, the most popular commercially available polyether is a very high melting plastic. This makes it considerably more difficult to fabricate finished parts from this material. These problems are solved by providing an aromatic polyether graft copolymer with improved solvent resistance and crystalline thermally reversible crosslinks. The graft copolymer is formed by converting the carboxyl groups of a carboxylated polyphenylene oxide polymer to ionic carbonyl groups in a suitable solvent, reacting pivalolactone with the dissolved polymer, and adding acid to the solution to produce the graft copolymer.

Bell, Vernon L. (inventor)

1987-01-01

238

[Dietary fats and cardiovascular health].  

Science.gov (United States)

Although dietary fat and its role in cardiovascular prevention has been one of the most extensively studied nutritional topics, it continues to be an ever-expanding research area. Particularly thanks to studies on Mediterranean diet, we now know that fat quality is more relevant than the amount of fat we eat in the diet. Thus, saturated and trans fats have been found to increase the risk of atherogenic disease. This is why it is recommended to substitute complex carbohydrates or unsaturated fat for unsaturated and trans fats with the aim of reducing saturated and trans fat intake to diet, stress the important role of monounsaturated and polyunsaturated fats as key nutrients in preventing cardiovascular disease in modern societies. Furthermore, a special type of polyunsaturated fatty acids, i.e. those of the omega-3 (n-3) series, is increasingly becoming essential nutrients for a healthy diet, especially in the case of children. Therefore, there is a rationale for four the Scientific Societies that are strongly committed to disseminate the benefits of a healthy diet in preventing cardiovascular disease, and to prepare a joint statement with the purpose of spreading improved knowledge on the importance of changing to a healthy diet with a well-balanced fat intake for industrialized populations. Accordingly, a multidisciplinary panel of experts from the following institutions has developed the present joint statement targeted at both adults and children of different ages: Spanish Society of Arteriosclerosis, Spanish Society of Family and Community Medicine, Spanish Association of Paediatrics, Spanish Society of Gastroenterology, Hepatology and Paediatric Nutrition and Dietetics, and Spanish Society for Food Sciences. PMID:21345757

Carrillo Fernández, L; Dalmau Serra, J; Martínez Álvarez, J R; Solà Alberich, R; Pérez Jiménez, F

2011-03-01

239

Treatment of oroantral fistula with autologous bone graft and application of a non-reabsorbable membrane  

Directory of Open Access Journals (Sweden)

Full Text Available Aim: The aim of the current report is to illustrate an alternative technique for the treatment of oroantral fistula (OAF, using an autologous bone graft integrated by xenologous particulate bone graft.Background: Acute and chronic oroantral communications (OAC, OAF can occur as a result of inadequate treatment. In fact surgical procedures into the maxillary posterior area can lead to inadvertent communication with the maxillary sinus. Spontaneous healing can occur in defects smaller than 3 mm while larger communications should be treated without delay, in order to avoid sinusitis. The most used techniques for the treatment of OAF involve buccal flap, palatal rotation - advancement flap, Bichat fat pad. All these surgical procedures are connected with a significant risk of morbidity of the donor site, infections, avascular flap necrosis, impossibility to repeat the surgical technique after clinical failure, and patient discomfort.Case presentation: We report a 65-years-old female patient who came to our attention for the presence of an OAF and was treated using an autologous bone graft integrated by xenologous particulate bone graft. An expanded polytetrafluoroethylene titanium-reinforced membrane (Gore-Tex ® was used in order to obtain an optimal reconstruction of soft tissues and to assure the preservation of the bone graft from epithelial connection.Conclusions: This surgical procedure showed a good stability of the bone grafts, with a complete resolution of the OAF, optimal management of complications, including patient discomfort, and good regeneration of soft tissues.Clinical significance: The principal advantage of the use of autologous bone graft with an expanded polytetrafluoroethylene titanium-reinforced membrane (Gore-Tex ® to guide the bone regeneration is that it assures a predictable healing and allows a possible following implant-prosthetic rehabilitation.

Adele Scattarella, Andrea Ballini, Felice Roberto Grassi, Andrea Carbonara, Francesco Ciccolella, Angela Dituri, Gianna Maria Nardi, Stefania Cantore, Francesco Pettini

2010-01-01

240

Histoplasma infection of aortofemoral bypass graft.  

Science.gov (United States)

Histoplasma infection of vascular grafts is extremely rare. To our knowledge, there are only 4 cases reported with Histoplasma capsulatum infection of the aortic graft. All had previous disseminated histoplasmosis and atherosclerotic peripheral vascular disease. They were treated surgically with explantation of the infected graft and reimplantation of new graft in extra-anatomic uninfected site. The authors present a new case of H capsulatum infection of aortofemoral bypass graft, but unlike the other cases, this case was managed without surgical intervention. PMID:23928546

Patel, Nishit; Bronze, Michael S

2014-05-01

 
 
 
 
241

MR angiography of peripheral arterial bypass grafts  

International Nuclear Information System (INIS)

This paper investigates the applicability of MR angiography in the evaluation of graft patency in peripheral vascular disease. MR angiography and digital subtraction angiography (DSA) were performed in 20 patients with 25 grafts, including two aortoiliac, ten aortofemoral, four femorofemoral, and nine femoropopliteal arterial bypass grafts. Retrospective blinded studies of each method were done separately. Patency was found by MR angiography in 20 of 25 grafts. Occlusion was noted in five and anastomotic aneurysm in one. These MR angiographic findings were in complete agreement with DSA findings. The above results seem to suggest a possible role of MR angiography in follow-up after peripheral vascular graft surgery

242

Vascular grafting strategies in coronary intervention  

Directory of Open Access Journals (Sweden)

Full Text Available With the growing need for coronary revascularizations globally, several strategies to restore blood flow to the heart have been explored. Bypassing the atherosclerotic coronary arteries with autologous grafts, synthetic prostheses and tissue-engineered vascular grafts continue to be evaluated in search of a readily available vascular graft with clinically acceptable outcomes. The development of such a vascular graft including tissue engineering approaches both in situ and in vitro is herein reviewed, facilitating a detailed comparison on the role of seeded cells in vascular graft patency.

KibretMequanint

2014-06-01

243

Fat Fisher zeroes  

Energy Technology Data Exchange (ETDEWEB)

We show that it is possible to determine the locus of Fisher zeroes in the thermodynamic limit for the Ising model on planar ('fat') phi{sup 4} random graphs and their dual quadrangulations by matching up the real part of the high and low temperature branches of the expression for the free energy. The form of this expression for the free energy also means that series expansion results for the zeroes may be obtained with rather less effort than might appear necessary at first sight by simply reverting the series expansion of a function g(z) which appears in the solution and taking a logarithm. Unlike regular 2D lattices where numerous unphysical critical points exist with non-standard exponents, the Ising model on planar phi{sup 4} graphs displays only the physical transition at c=exp(-2{beta})=1/4 and a mirror transition at c=-1/4 both with KPZ/DDK exponents ({alpha}=-1, {beta}=1/2, {gamma}=2). The relation between the phi{sup 4} locus and that of the dual quadrangulations is akin to that between the (regular) triangular and honeycomb lattices since there is no self-duality.

Janke, W.; Johnston, D.A. E-mail: des@ma.hw.ac.uk; Stathakopoulos, M

2001-11-05

244

The invisible fat.  

Science.gov (United States)

Childhood and adolescence are decisive periods in human life. Body composition and psychological changes determine nutritional requirements as well as eating and physical activity behavior variability. Aims of the present paper are to discuss recent advances in measurements for quantifying total body and regional adiposity, and for mapping adipose tissue distribution in order to evaluate metabolic risk factors in children. Among the new methods available for assessing pediatric body composition, magnetic resonance imaging (MRI) can serve as a reference method for measuring tissue and organ volumes because estimates is reliable independent of age. MRI is the method of choice for calibrating field methods designed to measure adipose tissue and skeletal muscle in vivo and is the only method available for measurement of internal tissues and organs. MRI can be used to validate measures of important molecular level components such as fat measured by dual energy X-ray absorptiometry and bioimpedance analysis. Moreover, the large gap in available information for certain topics makes MRI measurement a dynamic and growing scientific area of body composition investigation. PMID:17313413

Pietrobelli, Angelo; Malavolti, Marcella; Fuiano, Nicola; Faith, Myles S

2007-04-01

245

Evaluation of the graft flow reserve after coronary artery bypass grafting by stress {sup 201}Tl myocardial SPECT. Comparison between arterial grafts and venous grafts  

Energy Technology Data Exchange (ETDEWEB)

We performed stress {sup 201}Tl myocardial SPECT to evaluate ischemia and perfusion reserve after coronary artery bypass grafting (CABG). A total of 103 patients was performed stress {sup 201}Tl myocardial SPECT one month after CABG. Each patient`s myocardium was divided into 9 segments and visually evaluated using five grade scoring system (0=defect, 1=severe decrease, 2=moderate decrease, 3=mild decrease, 4=normal uptake). Eleven of 133 (8.27%) segments covered by patent venous grafts showed reversible {sup 201}Tl defect, however, 36 of 117 (30.8%) segments which covered by patent arterial grafts showed reversible {sup 201}Tl defect. This finding was observed more significantly in arterial grafts than in venous grafts (p<0.001). These finding suggests that arterial grafts have lower flow capacity than venous grafts at peak exercise. (author)

Ichikawa, Akihiro; Taki, Junichi; Nakajima, Kenichi; Kawasuji, Michio; Tonami, Norihisa [Kanazawa Univ. (Japan). School of Medicine

1997-01-01

246

Body fat, abdominal fat and body fat distribution related to VO(2PEAK) in young children  

DEFF Research Database (Denmark)

Abstract Objective. Aerobic fitness, defined as maximum oxygen uptake (VO(2PEAK)), and body fat measurements represent two known risk factors for disease. The purpose of this study was to investigate the relationship between VO(2PEAK) and body fat measurements in young children at a population-based level. Methods. Cross-sectional study of 225 children (128 boys and 97 girls) aged 8-11 years, recruited from a population-based cohort. Total lean body mass (LBM), total fat mass (TBF), and abdominal fat mass (AFM) were measured by dual-energy x-ray absorptiometry. Body fat was also calculated as a percentage of body mass (BF%) and body fat distribution as AFM/TBF. VO(2PEAK) was assessed by indirect calorimetry during maximal exercise test. Results. Significant relationships existed between body fat measurements and VO(2PEAK) in both boys and girls, with Pearson correlation coefficients for absolute values of VO(2PEAK) (0.22-0.36, P<0.05), and for VO(2PEAK) scaled by body mass (-0.38 - -0.70, P

Dencker, Magnus; Wollmer, Per

2011-01-01

247

Hydrophilic Silicone Resins Obtained by Radiation Grafting  

International Nuclear Information System (INIS)

N-vinylpyrrolidone was grafted radiochemically on a silicone resin by pre-irradiation in the presence of oxygen. Under these conditions, peroxide groups capable of initiating radical copolymerization are formed. The trapped radicals do not seem to make any contribution. An RTV (Room Temperature Vulcanization) type silicone resin was used, i. e. a poly(dimethylsiloxane) crosslinked by vinyl-silane bonds. The unsaturated product was transparent. The silicones containing phenyl groups as well as saturated resins were also studied. Irradiation with 60Co gamma rays was performed in the 10-kCi irradiator of the Radiation Applications Group (GAR) at Saclay. Brief pre-irradiation tests with an electron accelerator were also performed. The amount of polyvinylpyrrolidone(PVP) grafted depends on the pre-irradiation dose and dose-rate as well as on the temperature and duration of the grafting proper. These different parameters were analysed. The grafting efficiency of PVP can be as much as 60%. The grafted copolymers are more or less opaque and coloured sections show that grafting remains peripheral. The transparency can be restored by immersion in water. The swelling in water is such that the ratio of absorbed water to grafted PVP varies between 0.8 and 1.5. When the grafting efficiency is higher than 50%, it is observed that the grafted PVP redissolves after swelling. The redissolving is due to the breaking of the grafted chains. For grafting rates below 30%, the grafted PVP silicones have notably high thermal stability. Examination of some properties of the grafted PVP silicones shows the additive nature of the properties of the grafted copolymers. Reference is made to the possible applications of these products, especially in biology and medicine. (author)

248

Weight Gain and Saturated Fats  

Medline Plus

Full Text Available ... Site Map FAQs Contact Us Search MedlinePlus Health Topics Drugs & Supplements Videos & Cool Tools To use the ... Association concludes the type of fat in the foods you indulge in may make a difference in ...

249

Weight Gain and Saturated Fats  

Medline Plus

Full Text Available ... HealthDay October 16, 2014 Related MedlinePlus Pages ... to the holidays! However, a new study published in the journal of the American Heart Association concludes the type of fat in ...

250

Weight Gain and Saturated Fats  

Medline Plus

Full Text Available ... their diet. The muffins were made with either unsaturated sunflower oil or saturated palm oil. The study ... weight, but those who ate the muffins with unsaturated fat had lower bad LDL cholesterol levels, total ...

251

Weight Gain and Saturated Fats  

Medline Plus

Full Text Available ... Association concludes the type of fat in the foods you indulge in may make a difference in ... adulthood, it is important to avoid high-calorie foods and weight gain,” but these findings indicate it ...

252

The Thin-Fat Indian  

Diet. Physical inactivity. Stress. +. ? Prevention Trials are based on a gene + .... \\Vit B12. Red cell folate. Adjusted for sex, age and fat%; mat adiposity, protein \\intake ... Parthenon Study, Mysore, S India. • `800 Pregnancies. • 43% B. 12 \\deficient.

253

MRI of Hoffa's fat pad.  

Science.gov (United States)

The infrapatellar fat pad of Hoffa is commonly injured but rarely discussed in the radiological literature. Abnormalities within it most commonly are the consequences of trauma and degeneration, but inflammatory and neoplastic diseases of the synovium can be confined to the fat pad. The commonest traumatic lesions follow arthroscopy, but intrinsic signal abnormalities can also be due to posterior and superior impingements syndromes and following patellar dislocation. Infrapatellar plica syndrome may also be traumatic in aetiology. The precise aetiology of ganglion cysts is not understood; the principal differential diagnosis is a meniscal or cruciate cyst. Hoffa's fat pad contains residual synovial tissue, meaning that primary neoplastic conditions of synovium may originate and be confined to the fat pad. Inflammatory changes along the posterior border of the pad may also be used to help differentiate effusion from acute synovitis on unenhanced MR examinations. PMID:15221217

Saddik, D; McNally, E G; Richardson, M

2004-08-01

254

MRI of Hoffa's fat pad  

International Nuclear Information System (INIS)

The infrapatellar fat pad of Hoffa is commonly injured but rarely discussed in the radiological literature. Abnormalities within it most commonly are the consequences of trauma and degeneration, but inflammatory and neoplastic diseases of the synovium can be confined to the fat pad. The commonest traumatic lesions follow arthroscopy, but intrinsic signal abnormalities can also be due to posterior and superior impingements syndromes and following patellar dislocation. Infrapatellar plica syndrome may also be traumatic in aetiology. The precise aetiology of ganglion cysts is not understood; the principal differential diagnosis is a meniscal or cruciate cyst. Hoffa's fat pad contains residual synovial tissue, meaning that primary neoplastic conditions of synovium may originate and be confined to the fat pad. Inflammatory changes along the posterior border of the pad may also be used to help differentiate effusion from acute synovitis on unenhanced MR examinations. (orig.)

255

Fat in the dural sinus  

International Nuclear Information System (INIS)

Fat density in the dural sinus on computed tomography (CT) is described in eight cases. Of the eight cases, five had fat deposit in the torcular Herophili, and three in the superior sagittal sinus. This finding was incidentally found by CT and there was no common underlying disease in these cases. It is suggested that this finding represents normal adipose tissue in the dural sinus. (orig.)

256

Endovascular Stent-Graft Repair as a Late Secondary Procedure After Previous Aortic Grafts  

International Nuclear Information System (INIS)

Thoracic and abdominal aortic endovascular procedures as alternatives to aortic reoperations were studied in three different cases. An anastomotic aneurysm after previous thoracic aortic graft for coarctation, a second-stage elephant trunk repair (descending thoracic aortic aneurysm), and a secondary aneurysm proximal to a previous abdominal aortic graft were successfully treated with endovascular stent-grafts. During the follow-up period no lethal events or major aortic or graft-related complications were observed, except a type II endoleak in the anastomotic aortic aneurysm case. An endovascular stent-graft can be safely deployed into a previously implanted vascular graft, avoiding repeat surgery

257

Determining the degree of grafting for poly (vinylidene fluoride) graft-copolymers using fluorine elemental analysis  

International Nuclear Information System (INIS)

Acrylic acid (AAc) and styrene (St) were grafted onto poly (vinylidene fluoride) (PVDF) powder or membrane samples by pre-irradiation graft copolymerization. The grafted chains were proved by FT-IR spectroscopy analysis. The degree of grafting (DG) of the grafted PVDF was determined by fluorine elemental analysis (FEA) method, and was compared with the DGs determined by weighing method, acid-base back titration method and quantitative FT-IR method. The results show that the FEA method is accurate, convenient and universal, especially for the grafted polymer powders. (authors)

258

Body fat measurement in computed tomography image  

International Nuclear Information System (INIS)

We suggested an automatic fat range setting method in computed tomography to measure body fat. Quantitative measurement of body fat is important for the diagnosis and treatment of diseases related to obesity. A body fat measurement by computed tomography presents body fat volume quantitatively at a specific region. The method to set the body fat range in Hounsfield units proportional to the voxel's density in computed tomography images was not known. We suggested an automatic setting method of the histogram in the computed tomography image, and we show the body fat range for 20 persons and various region of person. (author)

259

Septal graft in laryngeal reconstruction  

International Nuclear Information System (INIS)

A 62-year-old woman presented with symptoms of dyspnea. Ultrasonography and computed tomography examinations revealed mass extending from the cricoid cartilage to the left lobe of thyroid gland and thyroid cartilage. Cytology revealed possibility of cartilaginous origin, which was proven to be chondrosarcoma (Grade 1) from the biopsy specimen obtained during panendosopy. She underwent one stage radical resection and immediate reconstruction of laryngeal skeleton defect by mucocartilaginous graft from the nasal septum. Her postoperative course was optimal with preservation of the laryngeal functions. Twenty-eight months postoperatively, she had to undergo total laryngectomy as a salvage procedure for the advanced local recurrence. We report on the relatively easy technique for functional reconstruction of the large laryngeal defect with the employment cartilage graft from the nasal septum. (author)

260

Assessment of aorto-coronary bypass graft patency and graft flow by contrast enhanced computed tomography  

International Nuclear Information System (INIS)

Recent advances in computed tomography have led to clinically useful imaging of the cardiovascular structures with remarkable resolution. In 44 patients with 66 aorto-coronary bypass grafts, the efficacy of contrast enhanced computed tomography to determine graft patency and estimate graft flow was studied. After the proper scanning level was selected by scout scans, sequential scans with a 5 seconds scanning time and a 5 seconds interscan period were performed during the rapid injection of a 30 ml bolus of contrast medium into an antecubital vein. Patency of grafts was determined by a characteristic enhancement with contrast medium that coincides with appearance of contrast in the aorta. Comparing CECT with conventional graft angiography, our results gave a 91% sensitivity for CECT detection of graft patency, a 91% specificity and a 91% accuracy. Variables, such as follows, were measured by plotting the time-density curve of dynamic scans. ?CT = increasing rate of CT number, Max CT = peak CT number - ?CT = clearance rate of CT number. The mean graft flow was measured intraoperatively by using an electromagnetic flowmeter. To determine if CECT can quantitate graft flow, correlation between the mean graft flow and variables was studied. There was significant correlation between the mean graft flow and -?CT of graft/ -?CT of Ao. (p<0.001). These findings indicates that CECT has promise as a safe and relatively noninvasive technique for determining bypass graft patency and estimating graft flow. (author)

 
 
 
 
261

Post-surgical complications of symphyseal block graft with and without soft tissue grafting  

Directory of Open Access Journals (Sweden)

Full Text Available Objectives: To determine whether soft tissue augmentation prior to block grafting will minimize post-block grafting soft tissue complications. Methods: This longitudinal controlled pilot study was conducted at the Faculty of Dentistry, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia from October 2010 to January 2013. Fourteen sites requiring block grafting were divided into 2 groups: Group A - 7 sites in 6 patients were subjected to monocortical block graft (control; and Group B - 7 sites in 6 patients were subjected to soft tissue graft through new tunnel technique, followed by monocortical block graft (test. Results: In Group A, 2 patients had wound dehiscence and graft exposure. The first that had an exposure of 3x4 mm resulted in 45% resorption of the graft. The second had an exposure of 4x5 mm followed by infection, which resulted in 75% resorption of the graft. In the other 5 cases, sites healed with no complications and minimal resorption (0-15%. In Group B - there were generalized 1-2 mm increases in the thickness of soft tissue following soft tissue graft. Recipient sites healed with no complications or infection following block grafting. Block graft resorption ranged from 0-15%. Conclusion: More complications were seen in those patients who did not receive soft tissue augmentation, thus demonstrating the importance of soft tissue preparation prior to block grafting, especially in patients having thin soft tissue. 

Ali S. AlGhamdi

2013-06-01

262

Autologous fat transplantation – animal models and methods for in vitro analysis of viability [Autologe Fetttransplantation – Tierversuche und Methoden für In-vitro-Vitalitätsanalysen  

Directory of Open Access Journals (Sweden)

Full Text Available [english] Since Peer presented his “cell survival theory” it is assumed that the grafted tissue will be implemented in some way into the host tissue. This lead to a big effort to produce a fat graft that is as much viable as possible. Various studies have been performed to analyse viability of fat grafts prepared with different techniques or protocols. All viability tests in vitro permit a non invasive way to analyse human fat grafts. But the influence of processing due to the viability test protocol on viability of fat grafts cannot be totally excluded. Furthermore no normative values exist and we do not know if the test will really measure the real viability of the fat graft. Therefore an in vitro test can only be rated by the following characteristics: a degree of tissue modification by the test itself, on adipose tissue, c ability to depict the relative rate of viable cells to the total cells of the graft. After all an ideal in vitro test still has to be invented, as all available tests do have their indications but also their disadvantages. Animal models offer in vivo analysis of fat survival, but results can not be transferred directly to humans. If autologous fat transplantation is performed for volume augmentation purposes the technique of lipofilling with the best volume survival rate and the least complications like oil cysts or calcifications would be superior. [german] Viele Studien zur Bestimmung der Vitalität von Fetttransplantaten bei der autologen Fetttransplantation sind bereits unternommen worden. Seit der Beschreibung der „cell survival theory“ durch Peer geht man davon aus, dass das Fetttransplantat in gewisser Weise in den Empfängerorganismus integriert wird. Daher ist die Gewinnung von möglichst vitalem Fettgewebe von großer Bedeutung. Vitalitätstests ermöglichen eine nichtinvasive Evaluation von humanen Fettgewebstransplantaten, allerdings kann hierbei eine Beeinflussung der Vitalität durch den Test per se nicht ausgeschlossen werden. Normalwerte existieren nicht und die tatsächliche Vitalität kann nicht bestimmt werden. Daher können diese Tests nur anhand folgender Kriterien beurteilt werden: a dem Grad der Gewebsveränderung durch den Test, b der Spezifität für Fettgewebe, c der Möglichkeit die relative Anzahl vitaler Zellen des Transplantates anzuzeigen. Ein idealer Vitalitätstest zur Fettgewebsdiagnostik muss noch entwickelt werden, alle bisherigen Tests haben entscheidende Vor-, und Nachteile. Tierversuche bieten die Möglichkeit der in vivo Diagnostik, aber die Ergebnisse können nicht direkt auf den Menschen übertragen werden. Falls eine autologe Fetttransplantation zur Gewebsaugmentation durchgeführt wird, kann diejenige Technik, welche die geringsten Komplikationsrate an Fettgewebsnekrosen oder Ölzysten bietet und den höchsten Volumenerhalt gewährleistet als am besten geeignet angesehen werden.

Herold, C.

2012-07-01

263

The genetics of fat distribution.  

Science.gov (United States)

Fat stored in visceral depots makes obese individuals more prone to complications than subcutaneous fat. There is good evidence that body fat distribution (FD) is controlled by genetic factors. WHR, a surrogate measure of FD, shows significant heritability of up to ?60%, even after adjusting for BMI. Genetic variants have been linked to various forms of altered FD such as lipodystrophies; however, the polygenic background of visceral obesity has only been sparsely investigated in the past. Recent genome-wide association studies (GWAS) for measures of FD revealed numerous loci harbouring genes potentially regulating FD. In addition, genes with fat depot-specific expression patterns (in particular subcutaneous vs visceral adipose tissue) provide plausible candidate genes involved in the regulation of FD. Many of these genes are differentially expressed in various fat compartments and correlate with obesity-related traits, thus further supporting their role as potential mediators of metabolic alterations associated with a distinct FD. Finally, developmental genes may at a very early stage determine specific FD in later life. Indeed, genes such as TBX15 not only manifest differential expression in various fat depots, but also correlate with obesity and related traits. Moreover, recent GWAS identified several polymorphisms in developmental genes (including TBX15, HOXC13, RSPO3 and CPEB4) strongly associated with FD. More accurate methods, including cardiometabolic imaging, for assessment of FD are needed to promote our understanding in this field, where the main focus is now to unravel the yet unknown biological function of these novel 'fat distribution genes'. PMID:24632736

Schleinitz, Dorit; Böttcher, Yvonne; Blüher, Matthias; Kovacs, Peter

2014-07-01

264

Fixation of tibial plateau fractures with synthetic bone graft versus natural bone graft: a comparison study.  

LENUS (Irish Health Repository)

The goal of this study was to determine differences in fracture stability and functional outcome between synthetic bone graft and natural bone graft with internal fixation of tibia plateau metaphyseal defects.

Ong, J C Y

2012-06-01

265

On mechanism of radiation ion graft polymerization  

International Nuclear Information System (INIS)

The mechanisms of initiation of radiation ion graft poiymerization anO growth of the grafted chains in the polymer matrix, are considered. The specific ion solvation is the principal factor, determining the solvent effect on the rate of the radiation ion graft. The ion graft rate is maximum in the point of the basic relaxation transition of the swelled polymer (glass-transition temperature). The radiation graft polymerization is considered as totality of radical and ion processes. The equation, determining the dependence of the ion process quota contribution, depending on dose rate and content of inhibitor admixtures (H2O) in the system is derived and analysed. The increase of the ion process quota contribution with increase of the dose rate is established. The ion process begins to be clearly manifest at the dose rate 103 Gy/s during the radiation graft copolymerization of styrene with acrylonitrile

266

Sources of Saturated Fat, Stearic Acid, & Cholesterol Raising Fat among the US Population, 2005–06  

Science.gov (United States)

The purpose of this research was to identify the contributions of specific foods to intake of saturated fat, stearic acid, and "cholesterol raising fat" (defined as saturated fat minus stearic acid) in the US population age 2 years and older.

267

FAT TISSUE DISTRIBUTION BETWEEN SUBCUTANEOUS AND INTERMUSCULAR FAT TISSUE IN SIMMENTAL AND BROWN BULLS  

Directory of Open Access Journals (Sweden)

Full Text Available Simmental and Brown bulls from progeny testing station were used to evaluate the effect of breed on fat tissue partition between subcutaneous and intermuscular fat. Bulls (37 Brown and 34 Simmental breed were slaughtered at the same degree of fatness. After slaughter carcasses were first cut into different carcass cuts and further on into lean meat, fat, bones and tendons. Fat was divided up into subcutaneous and intermuscular. Simmental bulls were heavier (average cold carcass side weight from Simmental bulls was 167 kg vs 147 kg from Brown bulls at the same percentage of total carcass fat (10.5 %. Breed has no effect on percentage of subcutaneous and intermuscular fat tissue nor on percentage of subcutaneous fat from total carcass fat. Simmental bulls had higher (p<0.05 subcutaneous fat percentage (subcutaneous fat in the cut /total fat in the cut in brisket and flank and lower (p<0.05 in shoulder than Brown bulls.

Silvester Žgur

2007-06-01

268

Evaluation of irradiated Dallon vascular grafts  

International Nuclear Information System (INIS)

Dallon24 vascular grafts sterilized radially or by autoclaving were the subject of our investigation on piglets weighting 20-30 kgs. The grafts were implanted into the surgical defect of the descending thoracic aorta, according to previously elaborated surgical model. On the basis of gross and microscopic findings it was proved that Dallon24 vascular grafts are suitable for the clinical use and that the radial sterilization does not change their biological properties. (author)

269

Characterization of radiation-induced grafting reactions  

International Nuclear Information System (INIS)

Various methods for characterization the initiators and products of grafting reactions (ESR spectroscopy, tracer technique, voltammetry, and polarography) are described. Recent developments and analytical techniques are considered. (author)

270

Nuclear accidents and bone marrow graft  

International Nuclear Information System (INIS)

In case of serious contamination, the only efficacious treatment is the bone marrow grafts. The graft types and conditions have been explained. To restrict the nuclear accidents consequences, it is recommended to: - take osseous medulla of the personnel exposed to radiations and preserve it , that permits to carry out rapidly the auto-graft in case of accidents; - determine, beforehand, the HLA group of the personnel; - to register the voluntary donors names and addresses, and their HLA group, that permits to find easily a compatible donar in case of allo-graft. (author)

271

Graft union formation in artichoke grafting onto wild and cultivated cardoon: an anatomical study.  

Science.gov (United States)

In order to develop a non-chemical method such as grafting effective against well-known artichoke soil borne diseases, an anatomical study of union formation in artichoke grafted onto selected wild and cultivated cardoon rootstocks, both resistant to Verticillium wilt, was performed. The cardoon accessions Belgio (cultivated cardoon) and Sardo (wild cardoon) were selected as rootstocks for grafting combinations with the artichoke cv. Romolo. Grafting experiments were carried out in the autumn and spring. The anatomical investigation of grafting union formation was conducted by scanning electron microscopy (SEM) on the grafting portions at the 3rd, 6th, 10th, 12th day after grafting. For the autumn experiment only, SEM analysis was also performed at 30 d after grafting. A high affinity between artichoke scion and cardoon rootstocks was observed, with some genotype differences in healing time between the two bionts. SEM images of scion/rootstock longitudinal sections revealed the appearance of many interconnecting structures between the two grafting components just 3d after grafting, followed by a vascular rearrangement and a callus development during graft union formation. De novo formation of many plasmodesmata between scion and rootstock confirmed their high compatibility, particularly in the globe artichoke/wild cardoon combination. Moreover, the duration of the early-stage grafting process could be influenced not only by the scion/rootstock compatibility, but also by the seasonal conditions, being favored by lower temperatures and a reduced light/dark photoperiod. PMID:23932643

Trinchera, Alessandra; Pandozy, Gianmarco; Rinaldi, Simona; Crinò, Paola; Temperini, Olindo; Rea, Elvira

2013-12-15

272

Prevention of fat embolism syndrome.  

Science.gov (United States)

Fat embolism syndrome is a condition of acute respiratory distress following long-bone trauma. This condition may involve not only the lungs but also a number of other body systems. The pathophysiology is not as yet clearly understood, however, intravasation of fat from long-bone fractures may play a role. Early recognition of the severity of injury both on clinical and biochemical grounds and early surgical stabilization of long bones may help to decrease its incidence. However, the best surgical technique with which to do this stabilization has not yet been clearly determined. Surgical and pharmacological techniques have been developed in an attempt to either decrease the intravasation of fat during long-bone stabilization or block the inflammatory cascade with varying degrees of efficacy. Ongoing research focuses on both the prevention and treatment of this condition. PMID:16990062

White, Timothy; Petrisor, Brad A; Bhandari, Mohit

2006-10-01

273

Industrial application of electron beams for grafting and vulcanization  

International Nuclear Information System (INIS)

The topics discussed are radiation graft polymerization; industrial application of radiation grafting - ion exchange membrane for a battery separator, ammonia adsorbent, non-flammable PE (polyethylene) foam; R and D on radiation grafting, radiation vulcanization of natural rubber

274

Weyl law for fat fractals  

CERN Document Server

It has been conjectured that for a class of piecewise linear maps the closure of the set of images of the discontinuity has the structure of a fat fractal, that is, a fractal with positive measure. An example of such maps is the sawtooth map in the elliptic regime. In this work we analyze this problem quantum mechanically in the semiclassical regime. We find that the fraction of states localized on the unstable set satisfies a modified fractal Weyl law, where the exponent is given by the exterior dimension of the fat fractal.

Spina, Maria E; Saraceno, Marcos

2010-01-01

275

Effect of bidispersity in grafted chain length on grafted chain conformations and potential of mean force between polymer grafted nanoparticles in a homopolymer matrix.  

Science.gov (United States)

In efforts to produce polymeric materials with tailored physical properties, significant interest has grown around the ability to control the spatial organization of nanoparticles in polymer nanocomposites. One way to achieve controlled particle arrangement is by grafting the nanoparticle surface with polymers that are compatible with the matrix, thus manipulating the interfacial interactions between the nanoparticles and the polymer matrix. Previous work has shown that the molecular weight of the grafted polymer, both at high grafting density and low grafting density, plays a key role in dictating the effective inter-particle interactions in a polymer matrix. At high grafting density nanoparticles disperse (aggregate) if the graft molecular weight is higher (lower) than the matrix molecular weight. At low grafting density the longer grafts can better shield the nanoparticle surface from direct particle-particle contacts than the shorter grafts and lead to the dispersion of the grafted particles in the matrix. Despite the importance of graft molecular weight, and evidence of non-trivial effects of polydispersity of chains grafted on flat surfaces, most theoretical work on polymer grafted nanoparticles has only focused on monodisperse grafted chains. In this paper, we focus on how bidispersity in grafted chain lengths affects the grafted chain conformations and inter-particle interactions in an implicit solvent and in a dense homopolymer polymer matrix. We first present the effects of bidispersity on grafted chain conformations in a single polymer grafted particle using purely Monte Carlo (MC) simulations. This is followed by calculations of the potential of mean force (PMF) between two grafted particles in a polymer matrix using a self-consistent Polymer Reference Interaction Site Model theory-Monte Carlo simulation approach. Monte Carlo simulations of a single polymer grafted particle in an implicit solvent show that in the bidisperse polymer grafted particles with an equal number of short and long grafts at low to medium grafting density, the short grafts are in a more coiled up conformation (lower radius of gyration) than their monodisperse counterparts to provide a larger free volume to the longer grafts so they can gain conformational entropy. The longer grafts do not show much difference in conformation from their monodisperse counterparts at low grafting density, but at medium grafting density the longer grafts exhibit less stretched conformations (lower radius of gyration) as compared to their monodisperse counterparts. In the presence of an explicit homopolymer matrix, the longer grafts are more compressed by the matrix homopolymer chains than the short grafts. We observe that the potential of mean force between bidisperse grafted particles has features of the PMF of monodisperse grafted particles with short grafts and monodisperse grafted particles with long grafts. The value of the PMF at contact is governed by the short grafts and values at large inter-particle distances are governed by the longer grafts. Further comparison of the PMF for bidisperse and monodisperse polymer grafted particles in a homopolymer matrix at varying parameters shows that the effects of matrix chain length, matrix packing fraction, grafting density, and particle curvature on the PMF between bidisperse polymer grafted particles are similar to those seen between monodisperse polymer grafted particles. PMID:21599087

Nair, Nitish; Wentzel, Nathaniel; Jayaraman, Arthi

2011-05-21

276

A review of 155 extra-anatomic bypass grafts  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Extra-anatomic bypass grafting has been used as treatment for patients with aorto-iliac disease who were considered unfit for aortic surgery. Eighty five percent of the patients had ischaemic pain at rest or skin necrosis. One hundred and three femorofemoral (FF) grafts, 40 axillounifemoral and 12 axillobifemoral grafts were performed. Femoropopliteal extension grafts were performed in 39 cases. The three year cumulative graft patency rate was 69% for FF grafts and 48% for both types of axill...

Foster, M. C.; Mikulin, T.; Hopkinson, B. R.; Makin, G. S.

1986-01-01

277

Design and development of multilayer vascular graft  

Science.gov (United States)

Vascular graft is a widely-used medical device for the treatment of vascular diseases such as atherosclerosis and aneurysm as well as for the use of vascular access and pediatric shunt, which are major causes of mortality and morbidity in this world. Dysfunction of vascular grafts often occurs, particularly for grafts with diameter less than 6mm, and is associated with the design of graft materials. Mechanical strength, compliance, permeability, endothelialization and availability are issues of most concern for vascular graft materials. To address these issues, we have designed a biodegradable, compliant graft made of hybrid multilayer by combining an intimal equivalent, electrospun heparin-impregnated poly-epsilon-caprolactone nanofibers, with a medial equivalent, a crosslinked collagen-chitosan-based gel scaffold. The intimal equivalent is designed to build mechanical strength and stability suitable for in vivo grafting and to prevent thrombosis. The medial equivalent is designed to serve as a scaffold for the activity of the smooth muscle cells important for vascular healing and regeneration. Our results have shown that genipin is a biocompatible crosslinker to enhance the mechanical properties of collagen-chitosan based scaffolds, and the degradation time and the activity of smooth muscle cells in the scaffold can be modulated by the crosslinking degree. For vascular grafting and regeneration in vivo, an important design parameter of the hybrid multilayer is the interface adhesion between the intimal and medial equivalents. With diametrically opposite affinities to water, delamination of the two layers occurs. Physical or chemical modification techniques were thus used to enhance the adhesion. Microscopic examination and graft-relevant functional characterizations have been performed to evaluate these techniques. Results from characterization of microstructure and functional properties, including burst strength, compliance, water permeability and suture strength, showed that the multilayer graft possessed properties mimicking those of native vessels. Achieving these FDA-required functional properties is essential because they play critical roles in graft performances in vivo such as thrombus formation, occlusion, healing, and bleeding. In addition, cell studies and animal studies have been performed on the multilayer graft. Our results show that the multilayer graft support mimetic vascular culture of cells and the acellular graft serves as an artery equivalent in vivo to sustain the physiological conditions and promote appropriate cellular activity. In conclusion, the newly-developed hybrid multilayer graft provides a proper balance of biomechanical and biochemical properties and demonstrates the potential for the use of vascular tissue engineering and regeneration.

Madhavan, Krishna

278

Biodegradability of poly(3-hydroxybutyrate) film grafted with vinyl acetate: Effect of grafting and saponification  

International Nuclear Information System (INIS)

Radiation-induced graft polymerization of vinyl acetate (VAc) onto poly(3-hydroxybutyrate) (PHB) film was carried out. At a degree of grafting higher than 5%, the grafted films (PHB-g-VAc) completely lost the enzymatic degradability that is characteristic of PHB due to the grafted VAc covering the surface of the PHB film. However, the biodegradability of the PHB-g-VAc films was recovered when the films were saponified in alkali solution under optimum conditions. Graft chains of the PHB-g-VAc film reacted selectively to become biodegradable polyvinyl alcohol (PVA). The biodegradability of the saponified PHB-g-VAc film increased rapidly with time

279

Grafted methylenediphosphonate ion exchange resins  

Science.gov (United States)

An ion exchange resin is disclosed that is comprised of an insoluble copolymer onto which are grafted pendent groups that provide 1.0 to about 10 mmol/g dry weight phosphorous. The pendent groups have the formula ##STR1## wherein R is hydrogen, a cation or mixtures thereof; and R.sup.1 is hydrogen or an C.sub.1 -C.sub.2 alkyl group. The resin also contains zero to about 5 mmol/g dry weight of pendent aromatic sulfonate groups. Processes for making and using an ion exchange-resin are also disclosed.

Trochimcznk, Andrzej W. (Knoxville, TN); Gatrone, Ralph C. (Plymouth, PA); Alexandratos, Spiro (Knoxville, TN); Horwitz, E. Philip (Naperville, IL)

1998-01-27

280

Substituting dietary saturated fat with polyunsaturated fat changes abdominal fat distribution and improves insulin sensitivity.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

AIMS/HYPOTHESIS: British dietary recommendations are to decrease total fat intake to less than 30 % of daily energy intake and saturated fat to less than 10 %. In practice, it is difficult for people to make these changes. It may be easier to encourage people to switch from a diet rich in saturated fatty acids to one rich in polyunsaturated fatty acids. METHODS: A total of 17 subjects - six people with Type II (non-insulin-dependent) diabetes mellitus, six non-obese and five obese people with...

Summers, Lk; Fielding, Ba; Bradshaw, Ha; Ilic, V.; Beysen, C.; Clark, Ml; Moore, Nr; Frayn, Kn

2002-01-01

 
 
 
 
281

Weight Gain and Saturated Fats  

Medline Plus

Full Text Available ... in early adulthood, it is important to avoid high-calorie foods and weight gain,” but these findings indicate it is “also important to consume sufficient amounts of polyunsaturated fats.” I’m Dr. Cindy Haines of HealthDay TV, ...

282

Saturated fats: what dietary intake?  

Science.gov (United States)

Public health recommendations for the US population in 1977 were to reduce fat intake to as low as 30% of calories to lower the incidence of coronary artery disease. These recommendations resulted in a compositional shift in food materials throughout the agricultural industry, and the fractional content of fats was replaced principally with carbohydrates. Subsequently, high-carbohydrate diets were recognized as contributing to the lipoprotein pattern that characterizes atherogenic dyslipidemia and hypertriacylglycerolemia. The rising incidences of metabolic syndrome and obesity are becoming common themes in the literature. Current recommendations are to keep saturated fatty acid, trans fatty acid, and cholesterol intakes as low as possible while consuming a nutritionally adequate diet. In the face of such recommendations, the agricultural industry is shifting food composition toward lower proportions of all saturated fatty acids. To date, no lower safe limit of specific saturated fatty acid intakes has been identified. This review summarizes research findings and observations on the disparate functions of saturated fatty acids and seeks to bring a more quantitative balance to the debate on dietary saturated fat. Whether a finite quantity of specific dietary saturated fatty acids actually benefits health is not yet known. Because agricultural practices to reduce saturated fat will require a prolonged and concerted effort, and because the world is moving toward more individualized dietary recommendations, should the steps to decrease saturated fatty acids to as low as agriculturally possible not wait until evidence clearly indicates which amounts and types of saturated fatty acids are optimal? PMID:15321792

German, J Bruce; Dillard, Cora J

2004-09-01

283

Weight Gain and Saturated Fats  

Medline Plus

Full Text Available ... right-hand corner of the player. Weight Gain and Saturated Fats HealthDay October 16, 2014 Related MedlinePlus ... cholesterol levels, total cholesterol/good HDL cholesterol ratios and had other positive indicators of heart health. On ...

284

Main: E2FAT [PLACE  

Full Text Available E2FAT S000417 03-Jun-2003 (last modified) kehi E2F-binding site found in many potential E2F targ ... s; most potential E2F targets identified in silico show ... a cell cycle-regulated expression; Y=T/C; see S000 ...

285

Differentiation of lard, chicken fat, beef fat and mutton fat by GCMS and EA-IRMS techniques.  

Science.gov (United States)

A study was conducted to differentiate lard, chicken fat, beef fat and mutton fat using Gas Chromatography Mass Spectrometry (GC-MS) and Elemental Analyzer-Isotope Ratio Mass Spectrometry (EA-IRMS). The comparison of overall fatty acid data showed that lard and chicken fat share common characteristics by having palmitic, oleic and linoleic acid as major fatty acids while beef and mutton fats shared common characteristics by possessing palmitic, stearic and oleic acid as major fatty acids. The direct comparisons among the fatty acid data, therefore, may not be suitable for discrimination of different animal fats. When the fatty acid distributional data was subjected to Principle Component Analysis (PCA), it was demonstrated that stearic, oleic and linoleic acids as the most discriminating parameters in the clustering of animal fats into four subclasses. The bulk carbon analysis of animal fats using EA-IRMS showed that determination of the carbon isotope ratios (?¹³C) would be a good indicator for discriminating lard, chicken fat, beef fat and mutton fat. This would lead to a faster and more efficient method to ascertain the source of origin of fats used in food products. PMID:23823911

Ahmad Nizar, Nina Naquiah; Nazrim Marikkar, Jalaldeen Mohamed; Hashim, Dzulkifly Mat

2013-01-01

286

FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness  

DEFF Research Database (Denmark)

A common single nucleotide polymorphism (SNP) of FTO (rs9939609, T/A) is associated with total body fatness. We investigated the association of this SNP with abdominal and peripheral fatness and obesity-related metabolic traits in middle-aged men through a broad range of fatness present already in adolescence.

Kring, Sofia I I; Holst, Claus

2008-01-01

287

The olecranon bone graft for nasal augmentation.  

Science.gov (United States)

The olecranon bone graft offers an alternative to the cranial bone when autogenous material is preferred in the repair of moderate deficiencies of the nasal dorsum. The predictably thick cortex of the olecranon allows the crafting of a customized implant, and minimal donor site morbidity makes it a safe alternative to the cranial graft. PMID:1570775

Hodgkinson, D J

1992-01-01

288

DIAGNOSTICS OF COMPATIBILITY OF GRAFTING COMPONENTS ??????????? ????????????? ??????????? ????????  

Directory of Open Access Journals (Sweden)

Full Text Available The article deals with the main point of worked out and experimentally tested express-metodology to estimate biological compatibility between stock and scion in the process of grafting. The article also identifies the main diagnostic signs characterizing both compatibility and incompability of grafting components

Bondorina I. A.

2011-09-01

289

Hump behind the shoulders (Dorsocervical fat pad)  

Science.gov (United States)

Buffalo hump; Dorsocervical fat pad ... Cause of dorsocervical fat pad includes any of the following: Certain medicines used to treat HIV or AIDS Long-term use of certain glucocorticoid medicines, ...

290

HealthLines: Facts About Fat  

Science.gov (United States)

... Current Issue Past Issues Health Lines Facts About Fat Past Issues / Fall 2008 Table of Contents For ... Writer, NLM Scientists are learning more about our fat cells, and their findings could explain why some ...

291

Protect Your Heart: Choose Healthy Fats  

Science.gov (United States)

... fat meats like regular ground beef, bologna, hot dogs, sausage, and spareribs • lard and shortening • palm oil ... it may put you at risk for heart attack or stroke. Step 3: Choose fats that can ...

292

Conjoined double internal mammary artery grafting.  

Science.gov (United States)

Double internal mammary artery (IMA) grafting to the coronary arteries was performed on 82 patients. In ten of them one IMA was used as a free graft, and was proximally connected to the other ("conjoined" double IMA), the indications being insufficient supply of adequate veins, diseased aortic wall, availability of only a short right IMA segment for free grafting, occluded left subclavian artery, and when distal and scattered lesions of relatively important vessels had to be bypassed. Additional sequential IMA anastomoses were performed in four patients and an additional sequential vein graft in a fifth. All patients became angina-free postoperatively and have remained so during observation up to 16 months. Recatheterization studies were performed in six patients and in all of them the IMA-to-IMA (n = 6) and distal anastomoses (n = 26) were patent. Conjoined double IMA grafting is an important option available to the cardiac surgeon for management of selected patients with coronary artery disease. PMID:7792554

Gurevitch, J; Barak, J; Miller, H I; Kramer, A; Paz, Y; Yakirevich, V

1994-01-01

293

Grafting of styrene onto fluoropolymers films  

Energy Technology Data Exchange (ETDEWEB)

Grafting of styrene onto poly(vinylidenefluoride) (PVDF) and poly(tetrafluoroethylene) (PTFE) films was studied for the synthesis of ion exchange membranes. Radiation-induced grafting of styrene onto PVDF and PTFE films was investigated by simultaneous method using a Co{sup 60} source. The films of PVDF and PTFE were irradiated at total dose of 20 to 120 kGy and chemical changes were monitored after contact with styrene. Films of PTFE and PVDF were immersed in styrene/toluene 1:1 and were submitted to gamma radiation. After irradiation the samples were evaluated at periods of 0, 7, 14, 21 and 28 days, at room temperature in order to measure the grafting degree. Results of infrared spectroscopic analysis (FTIR), differential scanning calorimetry (DSC), thermogravimetry analysis (TGA) and the degree of grafting (DOG) were evaluated. The characterization techniques showed that irradiated PVDF and PTFE films exhibited a much higher grafting degree at 120 kGy. (author)

Geraldes, Adriana N.; Zen, Heloisa A.; Parra, Duclerc F.; Lugao, Ademar B.; Linardi, Marcelo [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Centro de Quimica e Meio Ambiente], E-mail: angeral@ipen.br

2007-07-01

294

Pathogenesis of cardiac graft failure in children  

Directory of Open Access Journals (Sweden)

Full Text Available For many critical cardiac conditions such as cardio-myopathy, congenital heart defects, or arrhythmogenic disorders, cardiac transplantation is often an accepted treatment with optimistic one- and five-year survival rates of 90% and 75% in the pediatric patient population, respectively. However, poor long-term survival is a cause for concern, with cardiac graft failure being the leading cause in late mortality transplant recipients. Cardiac graft failure occurs through several mechanisms. However, the most common causes include cardiac allograft vasculopathy, myocardial fibrosis, and fibrofatty changes. Risk factors exacerbate these mechanisms through rejection, immunosuppressive drug side effects, hypertension, diabetes mellitus, renal dysfunction, and viral infection to increase the chance of cardiac graft failure. Changes in expression levels of various genes offer diagnostic potential for the future of cardiac transplantation. Through a comprehensive review of how multiple factors can lead a cardiac graft into failure, we hope to contribute to the longevity of cardiac grafts and pediatric heart transplant recipients.

Jenny Lin

2012-12-01

295

Saturated fat, carbohydrate, and cardiovascular disease1234  

Digital Repository Infrastructure Vision for European Research (DRIVER)

A focus of dietary recommendations for cardiovascular disease (CVD) prevention and treatment has been a reduction in saturated fat intake, primarily as a means of lowering LDL-cholesterol concentrations. However, the evidence that supports a reduction in saturated fat intake must be evaluated in the context of replacement by other macronutrients. Clinical trials that replaced saturated fat with polyunsaturated fat have generally shown a reduction in CVD events, although several studies showed...

Siri-tarino, Patty W.; Sun, Qi; Hu, Frank B.; Krauss, Ronald M.

2010-01-01

296

Luteinized fat in Krukenberg tumor: MR findings  

International Nuclear Information System (INIS)

To our knowledge, there is no description of the fat-containing Krukenberg tumor. We report on a case of Krukenberg tumor associated with luteinized fat, which showed hyperintensity on T1-weighted MR image. The diagnosis was surgically confirmed. Hyperintense portion of the Krukenberg tumor on T1-weighted image showed diminished signal intensity on fat-saturated, T1-weighted images. Krukenberg tumor should be considered in the differential diagnosis of ovarian masses when fat signal is seen. (orig.)

297

Imaging features of anterior cruciate ligament reconstruction graft insufficiency  

International Nuclear Information System (INIS)

Objective: To investigate the imaging features of anterior cruciate ligament (ACL) graft insufficiency. Methods: X-Ray and MR imaging examinations in 24 consecutive patients who had ACL reconstructive graft insufficiency were retrospectively evaluated for tunnel position, osteoarthrosis and its related complications. Follow-up arthroscopy showed 16 graft tears and 8 graft laxities. Fisher exact test was used to compare tunnel malpositions, the proportion of graft tear on MRI and osteoarthrosis between graft tear group and graft laxity group. Results: Two malpositions of tibial tunnel and 3 malpositions of femoral tunnel were seen in graft tear group. Three-malpositions of tibial tunnel and 4 malpositions of femoral tunnel were seen in graft laxity group. The proportion of tibial or femoral malposition showed no significant difference between the two groups (P=0.289, P=0.167). In graft tear group, 15 complete graft tears were diagnosed correctly, 1 partial tear was misdiagnosed as normal on MRI. In graft laxity group, 4 grafts were diagnosed as normal and 4 were considered as graft tear on MRI. A significant difference was seen between the two groups (P=0.028) in the proportion of graft tear diagnosed on MRI. Fourteen osteoarthrosis were seen in graft tear group and 5 in graft laxity group. No significant difference was seen between the two groups (P= 0.289) in the proportion of osteoarthrosis. Conclusion: The proportions of tunnel malposition and osteoarthrosis showed no significant difference between the graft tear group and graft Laxity group. Most graft tears can be diagnosed accurately on MRI, but some cases of graft laxity may be misdiagnosed for graft tear. (authors)

298

Inflorescence stem grafting made easy in Arabidopsis  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Plant grafting techniques have deepened our understanding of the signals facilitating communication between the root and shoot, as well as between shoot and reproductive organs. Transmissible signalling molecules can include hormones, peptides, proteins and metabolites: some of which travel long distances to communicate stress, nutrient status, disease and developmental events. While hypocotyl micrografting techniques have been successfully established for Arabidopsis to explore root to shoot communications, inflorescence grafting in Arabidopsis has not been exploited to the same extent. Two different strategies (horizontal and wedge-style inflorescence grafting have been developed to explore long distance signalling between the shoot and reproductive organs. We developed a robust wedge-cleft grafting method, with success rates greater than 87%, by developing better tissue contact between the stems from the inflorescence scion and rootstock. We describe how to perform a successful inflorescence stem graft that allows for reproducible translocation experiments into the physiological, developmental and molecular aspects of long distance signalling events that promote reproduction. Results Wedge grafts of the Arabidopsis inflorescence stem were supported with silicone tubing and further sealed with parafilm to maintain the vascular flow of nutrients to the shoot and reproductive tissues. Nearly all (87% grafted plants formed a strong union between the scion and rootstock. The success of grafting was scored using an inflorescence growth assay based upon the growth of primary stem. Repeated pruning produced new cauline tissues, healthy flowers and reproductive siliques, which indicates a healthy flow of nutrients from the rootstock. Removal of the silicone tubing showed a tightly fused wedge graft junction with callus proliferation. Histological staining of sections through the graft junction demonstrated the differentiation of newly formed vascular connections, parenchyma tissue and lignin accumulation, supporting the presumed success of the graft union between two sections of the primary inflorescence stem. Conclusions We describe a simple and reliable method for grafting sections of an Arabidopsis inflorescence stem. This step-by-step protocol facilitates laboratories without grafting experience to further explore the molecular and chemical signalling which coordinates communications between the shoot and reproductive tissues.

Nisar Nazia

2012-12-01

299

Graft irradiation abrogates graft-versus-host disease in combined pancreas-spleen transplantation  

International Nuclear Information System (INIS)

A model of combined pancreas-spleen transplantation (PST) was studied in LBN F1 recipients of Lewis grafts in order to evaluate the efficacy of pretransplant graft irradiation in preventing lethal graft-versus-host disease (GVHD). Recipients of unmodified PST uniformly developed severe GVHD and died (MST = 16.7 +/- 3.8 days). Whole body donor irradiation with either 500 or 250 rad prevented lethal GVHD. Similarly, ex vivo graft irradiation with either 1000 or 500 rad also resulted in normal weight gain, graft function, and host survival for the 6-week study period. Conversely, delay of graft irradiation until 3 days after transplantation failed to prevent this complication (MST = 15.8 +/- 3.7 days). Recipients of irradiated grafts displayed glucose tolerance tests that were identical to those in the control group indicating that the doses of radiation employed in these experiments were not deleterious to islet function. Irradiated spleen grafts appeared histologically normal at 6 weeks after transplantation. Cells derived from these grafts failed to stimulate lymph node enlargement in a popliteal lymph node assay for GVHD, suggesting that these spleens may have become repopulated with host cells. These experiments confirm that PST has the potential to cause lethal GVHD and suggest that pretransplant graft irradiation may be used to prevent its occurrence

300

FAT TISSUE DISTRIBUTION BETWEEN SUBCUTANEOUS AND INTERMUSCULAR FAT TISSUE IN SIMMENTAL AND BROWN BULLS  

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Simmental and Brown bulls from progeny testing station were used to evaluate the effect of breed on fat tissue partition between subcutaneous and intermuscular fat. Bulls (37 Brown and 34 Simmental breed) were slaughtered at the same degree of fatness. After slaughter carcasses were first cut into different carcass cuts and further on into lean meat, fat, bones and tendons. Fat was divided up into subcutaneous and intermuscular. Simmental bulls were heavier (average cold carcass side weight ...

Silvester Žgur; Marko ?epon

2007-01-01

 
 
 
 
301

Pancreaticoportal Fistula and Disseminated Fat Necrosis After Revision of a Transjugular Intrahepatic Portosystemic Shunt  

Energy Technology Data Exchange (ETDEWEB)

A 59-year old man with alcohol related cirrhosis and portal hypertension was referred for transjugular intrahepatic portosystemic shunt (TIPS) to treat his refractory ascites. Ten years later, two sequential TIPS revisions were performed for shunt stenosis and recurrent ascites. After these revisions, he returned with increased serum pancreatic enzyme levels and disseminated superficial fat necrosis; an iatrogenic pancreaticoportal vein fistula caused by disruption of the pancreatic duct was suspected. The bare area of the TIPS was subsequently lined with a covered stent-graft, and serum enzyme levels returned to baseline. In the interval follow-up period, the patient has clinically improved.

Klein, Seth J., E-mail: kleins@mir.wustl.edu; Saad, Nael [Washington University School of Medicine, Interventional Radiology Section, Mallinckrodt Institute of Radiology (United States); Korenblat, Kevin [Washington University School of Medicine, Division of Gastroenterology, Department of Internal Medicine (United States); Darcy, Michael D. [Washington University School of Medicine, Interventional Radiology Section, Mallinckrodt Institute of Radiology (United States)

2013-04-15

302

Polytetrafluoroethylene vein composite grafts across the knee.  

Science.gov (United States)

Fifteen Gore-tex vein composite femoral-popliteal artery bypass procedures were performed during the four year period of December 1975 to December 1979. Nine were performed for salvage of the limb and six, for incapacitating claudication. Preoperatively, all patients had an arteriographic evaluation of the outflow tract. CPR by the life-table method was 63 per cent at six years. Early failures were three occlusions within two months in patients with poor outflow. One late occlusion occurred at 16 months, and the limb was salvaged with a femoral tibial bypass graft. Another late occlusion was treated by thrombectomy at 24 months with continued patency. Late revision was carried out in one patient at seven months. This consisted of repair of a stenosis of the distal popliteal artery with salvage of the graft. Only two of ten grafts available for evaluation beyond one year have become occluded. All patients operated upon for claudication or with good runoff have patent grafts. On the contrary, none of the grafts to an isolated popliteal segment remained patent. When there is not sufficient autogenous saphenous vein available for femoral-popliteal bypass, the ready availability of a synthetic graft makes it an attractive choice. Nevertheless, our 63 per cent CPR at six years strongly suggests that the composite graft is a durable option. PMID:6612572

Scribner, R G; Beare, J P; Harris, E J; Sydorak, G R; Tawes, R L; Brown, W H

1983-09-01

303

Radiation-induced graft copolymerization to polyester, 18  

International Nuclear Information System (INIS)

Properties of polyester (polyethylene terephthalate) fibers grafted with acrylic acid (AA) and methacrylic acid were measured not only in the form of free acid but also in the form of sodium and calcium salts. Nearly the same moisture regain as that of cotton was obtained in the cases of sodium acrylate graft (AA-Na) and methacrylate graft (MAA-Na) at 14 and 18% graft respectively. Although the rate of water droplet absorption by the wicking test revealed that the rate increased with grafting, it is generally lower than that of cotton. Only AA-Na graft showed similar rate as that of cotton at 5% graft. All other grafts i.e. AA, AA-Ca, MAA and MAA-Na grafts showed lower rate than cotton even at higher percent graft. Results of frictional electricity test were similar, AA-Na graft showed satisfactory low static charge, whereas the effect of the grafting was insufficient in the cases of AA, MAA and MAA-Na grafts. Polyester fibers above 10% AA graft were dyed homogeneously to deep color with cationic and disperse dyes. AA, AA-Na and AA-Ca grafts showed almost the same dyeability. In the case of MAA grafts, only MAA-Na graft showed good dyeability. Fibers dyed with cationic dyes showed poor light fastness. Nor or very little change in tensile properties of polyester fibers were observed upon grafting of acrylic acid. However, strength and modulus of grafts decrease when AA grafts above 15% graft were converted to AA-Na by treatment in aqueous sodium bicarbonate solution. (auth.)

304

Surgical treatment of infected aortic grafts.  

Science.gov (United States)

An infection of an aortic prosthesis is a severe condition with high morbidity and mortality rates. Surgical treatment of an infected aortic graft or infected aortic stent-graft focuses on treatment of the infection and maintaining or restoring perfusion of the lower limbs. Over the years various reconstruction options have been introduced, each claiming to be the most successful in securing lower limb perfusion. Consensus about the optimum treatment strategy is lacking. The frail patient population and the relative rarity of the disease limits research on this topic which is an important reason for this lack of consensus. In order to determine which of the various treatment options is the most suitable to treat aortic graft infections, this systematic review was conducted of the available literature of the last 20 years. The search strategy and data collection were based on the guidelines of the Meta-analysis Of Observational Studies in Epidemiology (MOOSE). Appropriate inclusion and exclusion criteria were defined. A total of 862 possibly relevant papers were identified. After applying the in- and exclusion, data on mortality, morbidity and complications were extracted from a total of 93 papers. This review covers the various surgical treatment options available in the treatment of infected aortic (stent) grafts. Strategies concerning graft excision are discussed as are the advantages and disadvantages of the extra-anatomic reconstruction and its counterpart, the in situ reconstruction (using antibiotic-impregnated grafts, autologous vein grafts, fresh or cryopreserved allografts, and silver impregnated grafts). Available evidence was summarized and used to construct a clinical decision flowchart. All reconstruction options seem to have their pros and cons, and all have their use in specific situations. The treatment of infected aortic grafts must therefore be tailor-made. PMID:23207555

Berger, P; Van Herwaarden, J A; Harkisoen, S; De Vries, J P M; Ekkelenkamp, M; Moll, F L

2012-12-01

305

A reappraisal of saphenous vein grafting  

Directory of Open Access Journals (Sweden)

Full Text Available Autologous saphenous vein grafting has been broadly used as a bypass conduit, interposition graft, and patch graft in a variety of operations in cardiac, thoracic, neurovascular, general vascular, vascular access, and urology surgeries, since they are superior to prosthetic veins. Modified saphenous vein grafts (SVG, including spiral and cylindrical grafts, and vein cuffs or patches, are employed in vascular revascularization to satisfy the large size of the receipt vessels or to obtain a better patency. A loop SVG helps flap survival in a muscle flap transfer in plastic and reconstructive surgery. For dialysis or transfusion purposes, a straight or loop arteriovenous fistula created in the forearm or the thigh with an SVG has acceptable patency. The saphenous vein has even been used as a stent cover to minimize the potential complications of standard angioplasty technique. However, the use of saphenous vein grafting is now largely diminished in treating cerebrovascular disorders, superior vena cava syndrome, and visceral revascularization due to the introduction of angioplasty and stenting techniques. The SVG remains the preferable biomaterial in coronary artery bypass, coronary ostioplasty, free flap transfer, and surgical treatment of Peyronie disease. Implications associated with saphenous vein grafting in vascular access surgery for the purpose of dialysis and chemotherapy are considerable. Vascular cuffs and patches have been developed as an important and effective means of enhancing the patency rates of the grafts by linking the synthetic material to the receipt vessel. In addition, saphenous veins can be a cell source for tissue engineering. We review the versatile roles that saphenous vein grafting has played as well as its current status in therapy.

Yuan Shi-Min

2011-01-01

306

Playing with bone and fat  

DEFF Research Database (Denmark)

The relationship between bone and fat formation within the bone marrow microenvironment is complex and remains an area of active investigation. Classical in vitro and in vivo studies strongly support an inverse relationship between the commitment of bone marrow-derived mesenchymal stem cells or stromal cells to the adipocyte and osteoblast lineage pathways. In this review, we focus on the recent literature exploring the mechanisms underlying these differentiation events and discuss their implications relevant to osteoporosis and regenerative medicine.

Gimble, Jeffrey M.; Zvonic, Sanjin

2006-01-01

307

[Neuroimmunoendocrinology of the fat tissue].  

Science.gov (United States)

Recent information concerning the white fat tissue allows considering it as endocrine system involved in the neuro-immune-endocrine interactions in regulating various aspects of homeostasis. The contribution presented sums up the latest evidence of adipocyte secreting hormones (leptine and resistine), cytokine (TNF alpha), as well as shedlight on mechanisms, involved in control of energy metabolism, immune reactions and food intake monitoring. PMID:12004575

Akmaev, I G; Sergeev, V G

2002-01-01

308

Fat containing chylous mesenteric lymphangiomatosis  

International Nuclear Information System (INIS)

We have experienced an unusual case of mesenteric lymphangiomatosis in a 6-month-old male infant. Computed tomography (CT) disclosed fatty abdominal masses with attenuation coefficient being -5?-28 Hounsfield units (HU). Laparotomy disclosed innumerable small and large chyle containing masses in the mesentery as well as mesenteric root. Pathologically these were confirmed to be cavernous and cystic lymphangiomatosis. One must bear in mind the possibility of lymphangioma in case of fat containing mesenteric mass on CT

309

Low fat meat products - An overview  

Directory of Open Access Journals (Sweden)

Full Text Available Meat is an excellent source of valuable nutrients. Meat fat acts as a reservoir for flavor compounds and contributes to the texture of product. There are diverse possible strategies for developing low fat meat and meat products. Reducing the fat content in products leads to a firmer, rubbery, less juicy product with dark color and more cost. Other technological problems like reduction in particle binding, reduced cook yields, soft and mushy interiors, rubbery skin formation, excessive purge and shortened shelf life are also associated with reduction in fat levels. This paper describes Procedured of reducing fat content, Selection of additives, Protein, Carbohydrat and fat based fat replacer and Super critical fluid extraction. [Vet World 2009; 2(9.000: 364-366

E. Naga Mallika

310

Grafting heterogeneous catalyst with gamma radiation  

International Nuclear Information System (INIS)

A process for the production of a heterogeneous catalyst comprises the steps of: irradiating an organic macromolecular substrate or a metal substrate with ionising or ultra violet radiation in the presence of a monomer selected from the group consisting of o-, m-, or p- styryl diphenyl phosphine and o-, m- or p- phenyl acrylyl diphenyl phosphine, to graft the monomer to the substrate; and reacting the graft copolymer with a homogeneous catalyst selected from the group consisting of catalytic metal salts and catalytic organometallic complexes such that the graft copolymer conjugate becomes a ligand of the catalyst

311

Salvage of a failing dialysis graft by percutaneous creation of a jump bypass graft.  

Science.gov (United States)

Percutaneous salvage of failing arteriovenous grafts with diffuse disease or occlusion in the venous outflow remains an issue with no ideal solution. The present report describes a method of percutaneous creation of vascular bypasses in a patient with a failing graft. The patient had a long-segment stenosis in the venous outflow of a brachial-cephalic dialysis graft, and the graft was salvaged by conversion to a brachial-basilic graft. Notably, this method allowed the bypass to safely traverse a long distance (20 cm), and at 8 months, the graft remained functional and free of complications. In principle, this approach can be applied to different situations in which superficial bypass conduits are desired. PMID:17675628

Kuo, Michael D; Son, Dennis H; Miller, Franklin J

2007-08-01

312

Scoring System for Predicting Saphenous Vein Graft Patency in Coronary Artery Bypass Grafting  

Science.gov (United States)

The initial and long-term benefits of coronary artery bypass grafting depend upon maintaining the coronary blood flow supplied by the graft. In order to devise a scoring system for predicting graft patency, we evaluated presumptive correlations between saphenous vein graft patency and the characteristics of saphenous veins that were used as conduits in coronary revascularization. We prospectively evaluated 1,000 saphenous vein segments that were implanted in 403 consecutive patients who underwent on-pump coronary artery bypass grafting at our hospital from January 2006 through February 2009. Branches, varicosity, diameter, and wall thickness were evaluated, and a scoring system was created in order to obtain a value for each characteristic. The patients were postoperatively monitored for 1 year, and graft patency was then evaluated with the use of 64-slice multidetector computed tomography. Lesions were found in 12.3% of the grafts. All of the evaluated characteristics of the grafts had a significant correlation with saphenous vein graft flow (P <0.0001). Using the venous characteristics in our statistical analysis, we devised a formula to obtain a score (range, 4–12) to predict the patency of each graft. A cutoff score of 7 yielded 87.8% sensitivity and 82.8% specificity. Our scoring system has good prognostic value. We believe that it can assist surgeons in choosing the most appropriate conduit and target vessel for coronary artery bypass grafting, especially in high-risk patients who are particularly dependent on blood flow through saphenous vein grafts. PMID:20978562

Sarzaeem, Mahmood Reza; Mandegar, Mohammad Hossein; Roshanali, Farideh; Vedadian, Ali; Saidi, Bahare; Alaeddini, Farshid; Tabarestani, Nardin

2010-01-01

313

Study on radiation graft copolymerization of MMA onto SBS. Pt.1: Liquid phase radiation graft copolymerization  

International Nuclear Information System (INIS)

This paper introduces mainly experimental results of graft copolymerization of styrene-butadiene-styrene (SBS) with methyl methacrylate (MMA) in solution by ?-ray irradiation. Effects of irradiation dose and monomer concentration on mass increment and graft yield onto two types of SBS have been discussed. FTIR characterization of the irradiated samples showed that the monomer had been grated to the SBS molecular chains, while thermal performance of the graft products, SBS-g-MMA, was measured by DSC. (authors)

314

Design and Implementation of Log Structured FAT and ExFAT File Systems  

Directory of Open Access Journals (Sweden)

Full Text Available The File Allocation Table (FAT file system is supported in multiple Operating Systems (OS. Hence, FAT file system is universal exchange format for files/directories used in Solid State Drives (SSD and Hard disk Drives (HDD. The Microsoft Corporation introduced the new file system called Extended FAT file system (ExFAT to support larger size storage devices. The ExFAT file system is optimized to use with SSDs. But, Both FAT and ExFAT are not power fail safe. This means that the uncontrolled power loss or abrupt storage device removable from the computer system, during file system update, causes corruption of file system meta data and hence it leads to loss of data in storage device. This paper implements the Logging and Committing features to FAT and ExFAT file systems and ensures that the file system meta data is consistent across the abrupt power loss or device removal from the computer system.

Keshava Munegowda

2014-08-01

315

Spreader graft placement: A simplified technique for young surgeons.  

Science.gov (United States)

The spreader graft is a longitudinal graft placed between the dorsal septum and the upper lateral cartilage in a submucoperichondrial pocket. This graft has functional and aesthetic indications. Although placement and suturing of the spreader graft to the septum is an easy part of rhinoplasty for the experienced surgeon, it can be difficult and time-consuming for young surgeons. Here we suggest a very simple technique for easier placement and suturing of spreader grafts. PMID:25037303

Varedi, P; Bohluli, B; Bayat, M; Mohammadi, F

2014-10-01

316

Anterior Cruciate Ligament Graft Choices: A Review of Current Concepts  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The graft choice for anterior cruciate ligament (ACL) reconstruction continues to be controversial. There are several options available for the treating surgeon, including Bone Patellar Tendon Bone (BPTB) grafts, Hamstring tendon (HT) grafts, allografts and synthetic grafts. Within the last decade there have been several comparative trials and meta-analysis, which have failed to provide an answer with regards to the best graft available. The aim of this review is to understand the current con...

Dheerendra, Sujay K.; Khan, Wasim S.; Singhal, Rohit; Shivarathre, Deepak G.; Pydisetty, Ravi; Johnstone, David

2012-01-01

317

Grafting of different European beech (Fagus sylvatica L.) cultivars  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The survey was conducted in 2008 on the European beech (Fagus sylvatica L.) at the Faculty of Agriculture and Life Sciences, University of Maribor. We grafted four different cultivars: 'Pendula', 'Atropunica', 'Zlatia' and 'Tricolor'. The grafting took place in the spring using bench grafting approach combined with side wedge grafting technique. We investigated the impact of different cultivars on the success of grafting. For each cultivar we analysed the impact of rootstock thickness, lengt...

Cerar, Tina

2010-01-01

318

Graft Rejection and Graft Failure After Penetrating Keratoplasty or Posterior Lamellar Keratoplasty for Fuchs Endothelial Dystrophy  

DEFF Research Database (Denmark)

PURPOSE:: To compare the frequency of rejection episodes and graft failure because of surgical complications or rejection after Descemet stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PK) for Fuchs endothelial dystrophy. METHODS:: A total of 201 eyes of 201 consecutive patients with Fuchs endothelial dystrophy undergoing keratoplasty were included. One hundred two patients underwent DSAEK and 99 PK in the period January 1, 2000, to December 31, 2010. Postoperative topical steroid treatment was similar in the 2 groups. Most patients in the PK group received a short course of oral prednisolone, which was not prescribed for patients undergoing DSAEK. Patient records were retrospectively reviewed; rejection episodes and causes of graft failures were recorded, and Kaplan-Meier survival curves up to 5 years after surgery were computed and compared. RESULTS:: All rejection episodes and most graft failures occurred during the first 2 years after surgery. In this period, rejection episodes were noted in 16% of PK and in 5% of DSAEK-treated eyes (P = 0.03). During the first 5 years, significantly more DSAEK grafts than PK grafts had failed (P = 0.04) but only 2 PK-treated and no DSAEK-treated grafts failed because of rejection. CONCLUSION:: The frequency of graft rejection episodes is higher after PK than DSAEK for primary endothelial disease, despite the use of oral prednisolone in the PK group. Early graft failure is more common after DSAEK than after PK, whereas graft failure because of previous rejection episodes is uncommon after DSAEK and PK.

Hjortdal, Jesper; Pedersen, Iben B

2013-01-01

319

Grafting of Methacrylonitrile and Ethyl Methacrylate onto Jute Fibre: Physico-chemical Characteristics of Grafted Jute  

Science.gov (United States)

Modification of bleached jute fibre was done by graft co-polymerization with vinyl monomers e.g. methacrylonitrile and ethyl methacrylate, in aqueous medium using H2O2-Na2S2O3 as redox initiators. To make the process efficient, the optimized polymerization condition was established. The maximum percent grafting and grafting efficiency obtained at optimum grafting condition were 11.3 and 20.4% for MAN, respectively and that of 17.6 and 27.5% for EMA. Modification of bleached jute fibre with MAN and EMA reduced the loss in breaking strength and the yellowing on exposure to sunlight in air.

Mondal, Md. Ibrahim H.; Islam Farouqui, Faisul; Abu Hanif, Md.; Shafiur Rahman, G. M.; Asadul Hoque, Md.

2005-10-01

320

Further understanding of fat biology: lessons from a fat fly.  

Science.gov (United States)

Obesity is a leading risk factor for insulin resistance, hypertension, hyperlipidemia, and cardiovascular complications, collectively referred to as metabolic diseases. Given the prevalence of obesity and its associated medical problems, new strategies are required to prevent or treat obesity and obesity-related metabolic effects. Here we summarize contributors of obesity, and molecular mechanisms controlling adipogenesis from studies in mammalian systems. We also discuss the possibilities of using Drosophila as a genetic model system to advance our understanding of players in fat biology. PMID:19887892

Hong, Joung-Woo; Park, Kye Won

2010-01-31

 
 
 
 
321

Buccal Mucosal Graft in Repeat Urethroplasty  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Introduction: Our aim was to evaluate the efficacy of a tubed buccal mucosal graft in repeat urethroplasty for patients with urethral stricture and failed previous operations.

Gholamreza Pourmand; Sepehr Salem; Alireza Sina; Hooman Djaladat; Abdorasol Mehrsai

2005-01-01

322

Mechanical Bench Grafting for Apple Propagation  

Directory of Open Access Journals (Sweden)

Full Text Available Mechanically and manually prepared stock and scion for bench grafting were adopted in four phases for apple propagation i.e., mechanically made stock and manually prepared scion, second phase was vice versa while in third stage both the stock and scion were prepared mechanically. In fourth operation all the grafting process was performed by hand made scion and stock. Maximum sprouting and success percentage of 93.2 and 83.2 respectively was recorded in the mechanically prepared scion and stock. Results proved that this operation was also the most efficient which took 95.4 minutes only to graft hundred plants of apple. In conclusion mechanical technique for bench grafting in apple propagation was recorded as the best and efficient method.

Muhammad Ashraf Sumrah

2002-01-01

323

Iliac crest reconstruction after tricortical graft harvesting.  

Science.gov (United States)

Twenty-eight patients underwent anterior iliac crest reconstruction after the harvesting of autogenous tricortical graft. The anterior iliac crest was reconstructed using the resected rib from the thoracoabdominal approach. The authors evaluated graft site pain and residual deformity, radiographic evidence of rib incorporation, and the incidence of lateral femoral cutaneous nerve injury. There were no reports of graft site pain greater than "acceptable" levels, requiring nonnarcotic analgesics on an intermittent basis and not interfering with activities of daily living. Four lateral femoral cutaneous nerve neuropraxias were recorded, none of clinical significance. The authors advocate the use of autogenous tricortical anterior iliac crest bone graft when performing reconstructive spinal surgery, followed by reconstruction of the iliac crest with the resected rib from the surgical approach. PMID:7919644

Harris, M B; Davis, J; Gertzbein, S D

1994-06-01

324

Nutritional and Health Effects of Dietary Fats  

Directory of Open Access Journals (Sweden)

Full Text Available In the 80`s and early 90`s, nutrition recommendations for the prevention of developing coronary heart disease called for a reduction of total fat in the diet through the substitution of carbohydrate for fat. However, the current scientific evidence does not support a position that a reduction in total fat has a beneficial effect on coronary heart disease, or risk factors for coronary heart disease. The cumulative evidence from recent scientific literature suggests that unless there is a concomitant reduction in saturated fat and trans fatty acids, a reduction in total fat will not lower the risk of developing coronary heart disease. It was also established during the last decade that increased intakes of dietary monounsaturated and polyunsaturated fats, in particular those fats containing moderate amounts of n-3 fatty acids, might play a role in reducing the risk of cardiovascular disease. The fatty acid composition of canola oil is consistent with current nutrition recommendations aimed at reducing the dietary amount of saturated fat and increasing the amounts of monounsaturated and n-3 fats. Canola is characterized by a low level of saturated fatty acids. It is also characterized by high level of monounsaturated fatty acids (viz. oleic acid and moderate level of n-3 fatty acids, in the form of alpha-linolenic acid. Clinical and epidemiological studies have shown that canola oil is one of the most desirable source of dietary fat in terms of human health.

W.M. Nimal Ratnayake

2004-01-01

325

Graft Union Formation in Tomato Plants: Peroxidase and Catalase Involvement  

Science.gov (United States)

• Background and Aims The use of grafted plants in vegetable crop production is now being expanded greatly. However, few data are available on the formation of graft unions in vegetables. In this work, the structural development of the graft union formation in tomato plants is studied, together with the possible relationship with activities of peroxidases and catalases. • Methods Tomato (Lycopersicon esculentum Mill.) seedlings of cultivar Fanny were grafted on the rootstock of cultivar AR?9704 using the ‘tongue approach grafting’ method, and were grown in a crop chamber. A study of the structural development of the graft union and the involvement of peroxidases and catalases in the process of graft formation was carried out during the first stages of the graft union (4, 8 and 15 d after grafting). • Key Results Observation of the structure of the graft union showed formation of xylem and phloem vessels through the graft union 8 d after grafting. In addition, root hydraulic conductance, L0, indicate that the graft union is fully functional 8 d after grafting, which coincided with an increase of peroxidase and catalase activities. • Conclusions These results suggest that increased peroxidase and catalase activities might be implicated in graft development in tomato plants. PMID:14630693

FERNÁNDEZ?GARCÍA, NIEVES; CARVAJAL, MICAELA; OLMOS, ENRIQUE

2004-01-01

326

Effect of different grafting methods for absorption, translocation and distribution of 59Fe in apple trees  

International Nuclear Information System (INIS)

The test result with 59Fe demonstrate that the iron content in leaves by belly grafting is higher than that by cleft grafting and cutting grafting, and the content of chlorophyll in leaves and height and diameter of apple seedling by belly grafting is larger than cleft grafting and cutting grafting too. It is important to replace cleft grafting and cutting grafting with belly grafting as a method of top-working to correct chlorosis and improve growth of new cultivar

327

Grafting of a LLDPE using gamma irradiation  

International Nuclear Information System (INIS)

In this investigation, the grafting of a commercial linear low-density polyethylene (LLDPE) with different concentrations of diethyl maleate (DEM, 5 and 15 wt.%) was carried out at different absorbed doses from a cobalt-60 source of gamma rays (0, 15, 30, 50, 100, 200 kGy). This process was performed in a decalin solution at 10% w/v to obtain a homogeneous dispersion of the monomer into the polyethylene matrix. The grafting degree was estimated by means of FTIR using a calibration curve reported in literature. Thermal properties of the functional polymers were studied by thermogravimetric analysis (TGA). Melt flow index (MFI) values were also taken. The results found indicate that the grafting degree increases as the concentration of DEM in the reaction mixture and the absorbed doses are increased upto 100 kGy, as expected. However, the behavior at higher doses is attributed to secondary reactions such as long-chain branching and/or crosslinking, which are faster than radical reactions responsible for the grafting of the DEM onto the polymeric chain. This fact was ascertained by the decrease of the MFI values as the applied irradiation was increased, irrespective of the quantity of DEM used in the grafting reaction. Therefore, in order to obtain a high grafting degree, the absorbed dose should be estimated carefully. Initial degradation temperatures of the grafted PEs decreased when the gamma irradiation dose was higher than 100 kGy. This indicates that the thermal stability decreases as higher doses are applied to the material, which is associated to branching and crosslinking. The grafting degree never exceeded 0.3 mol%, which demonstrates the low efficiency of the functionalization procedure here presented

328

Fusarium incarnatum/equiseti hemodialysis graft infection  

Directory of Open Access Journals (Sweden)

Full Text Available Hemodialysis graft infections typically occur as a result of contamination by skin flora at the time of insertion or become secondarily infected after high-grade bacteremia. Infection of implanted vascular devices with filamentous fungi is rare. We report a case of infection of an implanted polytetrafluoroethylene dialysis graft with Fusarium incarnatum/equiseti that did not grow in cultures of tissue but was identified by molecular means.

Jeffery D. Punch

2010-08-01

329

Mechanical Bench Grafting for Apple Propagation  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Mechanically and manually prepared stock and scion for bench grafting were adopted in four phases for apple propagation i.e., mechanically made stock and manually prepared scion, second phase was vice versa while in third stage both the stock and scion were prepared mechanically. In fourth operation all the grafting process was performed by hand made scion and stock. Maximum sprouting and success percentage of 93.2 and 83.2 respectively was recorded in the mechanically prepared scion and stoc...

Muhammad Ashraf Sumrah; Allah Bakhsh; Zahid Hussain; Shafique Ahmad

2002-01-01

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422

Local graft irradiation in renal transplant rejection  

International Nuclear Information System (INIS)

From 1977 to 1988, of 142 renal transplantations, seven recipients (4.9%) received local graft irradiation following rejective reaction refractory to antirejection medical managements. Concurrent with the administration of pulsed high dose methylprednisolone and other antirejection medical managements, the graft was irradiated with a total dose of 6.0 Gy-150 cGy per fraction every other day at the midplane of the graft using two opposing portals of 4MX Linac. The fields were defined by palpation and echography. All patients had improvements in serum creatinine on the 10th day after beginning the irradiation. Four patients with peripheral lymphocytosis during the irradiation combined with pulsed high dose methylprednisolone improved in renal functions. On the other hand, out of 3 patients with lymphcytopenic changes, in two the transplanted graft was removed due to deteriorations, and the other patient is currently suffering from chronic rejection. Local graft irradiation can be useful in maintaining a rejective graft and reversing its functions in some patients whose rejective reaction failed to respond to the antirejection medical managements. (author)

423

Additive effects in radiation grafting and curing  

International Nuclear Information System (INIS)

Full text: Detailed studies on the accelerative effect of novel additives in radiation grafting and curing using acrylated monomer/oligomer systems have been performed in the presence of ionising radiation and UV as sources. Methyl methacrylate (MMA) is used as typical monomer for these grafting studies in the presence of the additives with model backbone polymers, cellulose and propropylene. Additives which have been found to accelerate these grafting processes are: mineral acid, occlusion compounds like urea, thermal initiators and photoinitiators as well as multifunctional monomers such as multifunctional acrylates. The results from irradiation with gamma rays have also been compared with irradiation from a 90W UV lamp. The role of the above additives in accelerating the analogous process of radiation curing has been investigated. Acrylated urethanes, epoxies and polyesters are used as oligomers together with acrylated monomers in this work with uv lamps of 300 watts/inch as radiation source. In the UV curing process bonding between film and substrate is usually due to physical forces. In the present work the presence of additives are shown to influence the occurrence of concurrent grafting during cure thus affecting the nature of the bonding of the cured film. The conditions under which concurrent grafting with UV can occur will be examined. A mechanism for accelerative effect of these additives in both grafting and curing processes has been proposed involving radiation effects and partitioning phenomena

424

Graft-copolymerization onto carbon black  

International Nuclear Information System (INIS)

Radiation-induced graft copolymerization of vinyl monomer onto carbon black was performed. During the ?-ray- and electron beam-induced polymerization (In-source), or the electron beam post-polymerization, the graft-copolymerization behavior was affected by the kinds of both carbon blacks and monomers, i.e. the smaller the size of carbon black particles, the higher the apparent grafted fraction. Homopolymer in the grafted carbon black samples was washed out by the solvent of the polymer, and the extracted polymer seemed to be dimer or trimer of the used monomer. In the case of the post-polymerization with the pre-irradiation doses of 50 Mrad, homopolymer was hardly observed. The polymer sheets of plastics or rubbers with grafted carbon black had an electrical conductivity unalterable considerably by the heating cycles. The particles of grafted carbon black in the sheet might be kept much more at the surface layer within 100 nm depth than at the inner layer. (author)

425

CUTTINGS AND GRAFTING IN ROOTSTOCKS OF TOMATO  

Directory of Open Access Journals (Sweden)

Full Text Available When performing in plants by grafting methods slit at the time of grafting is discarded cup rootstock. In this context, the aim of this work is to evaluate the technique of cutting in tomato plants that exhibit characteristics for use as rootstocks for tomato grafting and attachment provided by clones Cup compared to rootstocks propagated by seeds . For execution of the work, two experiments were conducted in the agricultural year 2013, for the first experiment was rooting three rootstocks: 1 wild species Solanum pennellii 'LA716', 2 access mini-tomato 6889; and 3 Witness (tomato Santa Cruz Kada® for the second experiment we evaluated the handle grafting rootstocks propagated by cuttings, compared to the same propagated by seeds. For the first experiment, treatments rootstocks access mini-tomato 6889 and witness, provided the greatest percentage of cuttings. For the second experiment, to evaluate the variable takes grafting, it was found that tomato rootstocks propagated by cuttings provide a good grip grafting the same or similar propagated by seeds.

A. R. Zeist

2014-09-01

426

Biodiesel via hydrotreating of fat  

DEFF Research Database (Denmark)

Biodiesel production via transesterification to fatty acid alkyl esters is rising rapidly worldwide due to the limited availability of fossil resources and the problems of global warming. Often, however, the use of 2nd-generation feedstock like animal waste fat and trap greases etc. is made difficult especially by the high amount of free fatty acids (FFA) in these raw materials. Another way to utilise such feedstock could be through the complete deoxygenation of the fuel, i.e. by hydrogenation and decarboxylation of the fat itself. Hydrotreating of fats is a procedure very well suited for existing petroleum refineries, and could be applied in mixture with existing hydrotreating of for instance vacuum gas oil [1,2]. As is shown in literature, both hydrogenation and decarboxylation of the fat may occur under such circumstances [2-4]. 9 g of a model mixture of 3 % oleic acid (C18:1), 7 % tripalmitin (C16:0) and 90% n-tetradecane (C14) in molar ratios was hydrotreated by 0.2 g of a 5%wt Pt/Al2O3 catalyst. The mixture was treated with 10 to 30 bar H2 in an autoclave at temperatures between 250 and 375°C, and samples for GC analysis was taken out after 1, 2, 5 and 20 hours to track the extent of reaction. Thus, the yields of pentadecane (C15) to octadecane (C18) could be monitored by GC analysis, thus indicating the conversions of FFA and tripalmitin. This procedure makes it possible to monitor and distinguish hydrogenation (resulting in hexadecane, C16, and octadecane, C18) from decarboxylation (resulting in pentadecane, C15, and heptadecane, C17) of triglyceride and fatty acid. Even in this hydrogen-rich atmosphere, the dominant reaction above 300ºC is decarboxylation of the acid and ester functionalities, thus limiting the consumption of hydrogen. Temperatures below 300°C are not well suited for the treating, as primarily the saturation of oleic acid to stearic acid (C18:0) is observed, with low conversions of fatty acid and triglyceride. [1] Stumborg, M., Wong, A. and Hogan, E., Bioresour. Technol. 56 (1996) 13 [2] Huber, G.W., O’Connor, P. and Corma, A., Appl. Catal. A. 329 (2007) 120 [3] Kubickova, I., Snåre, M., Eränen, K., Mäki-Arvela, P. and Murzin, D. Yu., Catal. Today, 106 (2005) 197 [4] Mäki-Arvela, P., Kubickova, I., Snåre, M., Eränen, K. and Murzin, D. Yu., Energy Fuels, 21 (2007) 31

Madsen, Anders Theilgaard; Ahmed, El Hadi

427

Fat Manifolds and Linear Connections  

CERN Document Server

In this unique book, written in a reasonably self-contained manner, the theory of linear connections is systematically presented as a natural part of differential calculus over commutative algebras. This not only makes easy and natural numerous generalizations of the classical theory and reveals various new aspects of it, but also shows in a clear and transparent manner the intrinsic structure of the associated differential calculus. The notion of a “fat manifold” introduced here then allows the reader to build a well-working analogy of this “connection calculus” with the usual one.

De Paris, Alessandro

2008-01-01

428

DIETARY FAT AND SPORTS NUTRITION: A PRIMER  

Directory of Open Access Journals (Sweden)

Full Text Available The general public's view of macronutrients has undergone sweeping changes in recent years. Dietary fats are a key example. Since the anti-fat health education initiatives of the 1980s and early 1990s, certain dietary fats have been increasingly recognized as actually beneficial to health. Athletes, like the mainstream populace, are now getting the message that wise dietary fat (triacylglycerol choices offer essential fatty acids, blood lipid management, maintained endocrine and immune function, inflammation control, metabolic effects and even potential body composition and performance benefits. Toward this end, many companies now sell specialty dietary fat supplements and recognized health authorities have begun recommending them to certain populations. This review will cover data regarding the physiology, dietary needs, food sources, and potential benefits and risks most relevant to athletes. Practical suggestions for incorporating healthy fats will be made. Both food-source and supplemental intakes will be addressed with interrelationships to health throughout.

Lonnie M. Lowery

2004-09-01

429

Radionuclide investigations of intestinal fat absorption  

International Nuclear Information System (INIS)

Analysis of the use of a simple and effective method for the assessment of intestinal fat absorption with the help of external radiometry of the abdominal area using a ?-radiation collimated detector and whole-body radiometry has shown that a coefficient of intestinal fat absorption in patients in the preoperative period does not demonstrate a statistically significant difference from the respective normal one. Gastrectomy with placing esophago-secal anastomosis disabling the duodenum, leads to considerable deterioration of fat absorptive function

430

Dietary fat intake, supplements, and weight loss  

Science.gov (United States)

Although there remains controversy regarding the role of macronutrient balance in the etiology of obesity, the consumption of high-fat diets appears to be strongly implicated in its development. Evidence that fat oxidation does not adjust rapidly to acute increases in dietary fat, as well as a decreased capacity to oxidize fat in the postprandial state in the obese, suggest that diets high in fat may lead to the accumulation of fat stores. Novel data is also presented suggesting that in rodents, high-fat diets may lead to the development of leptin resistance in skeletal muscle and subsequent accumulations of muscle triacylglycerol. Nevertheless, several current fad diets recommend drastically reduced carbohydrate intake, with a concurrent increase in fat content. Such recommendations are based on the underlying assumption that by reducing circulating insulin levels, lipolysis and lipid oxidation will be enhanced and fat storage reduced. Numerous supplements are purported to increase fat oxidation (carnitine, conjugated linoleic acid), increase metabolic rate (ephedrine, pyruvate), or inhibit hepatic lipogenesis (hydroxycitrate). All of these compounds are currently marketed in supplemental form to increase weight loss, but few have actually been shown to be effective in scientific studies. To date, there is little or no evidence supporting that carnitine or hydroxycitrate supplementation are of any value for weight loss in humans. Supplements such as pyruvate have been shown to be effective at high dosages, but there is little mechanistic information to explain its purported effect or data to indicate its effectiveness at lower dosages. Conjugated linoleic acid has been shown to stimulate fat utilization and decrease body fat content in mice but has not been tested in humans. The effects of ephedrine, in conjunction with methylxanthines and aspirin, in humans appears unequivocal but includes various cardiovascular side effects. None of these compounds have been tested for their effectiveness or safety over prolonged periods of time.

Dyck, D. J.

2000-01-01

431

Physical properties of agave cellulose graft polymethyl methacrylate  

Energy Technology Data Exchange (ETDEWEB)

The grafting polymerization of methyl methacrylate and Agave cellulose was prepared and their structural analysis and morphology were investigated. The grafting reaction was carried out in an aqueous medium using ceric ammonium nitrate as an initiator. The structural analysis of the graft copolymers was carried out by Fourier transform infrared and X-ray diffraction. The graft copolymers were also characterized by field emission scanning electron microscopy (FESEM). An additional peak at 1732 cm{sup ?1} which was attributed to the C=O of ester stretching vibration of poly(methyl methacrylate), appeared in the spectrum of grafted Agave cellulose. A slight decrease of crystallinity index upon grafting was found from 0.74 to 0.68 for cellulose and grafted Agave cellulose, respectively. Another evidence of grafting showed in the FESEM observation, where the surface of the grafted cellulose was found to be roughed than the raw one.

Rosli, Noor Afizah; Ahmad, Ishak; Abdullah, Ibrahim; Anuar, Farah Hannan [Polymer Research Centre (PORCE), School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi Selangor (Malaysia)

2013-11-27

432

Physical properties of agave cellulose graft polymethyl methacrylate  

Science.gov (United States)

The grafting polymerization of methyl methacrylate and Agave cellulose was prepared and their structural analysis and morphology were investigated. The grafting reaction was carried out in an aqueous medium using ceric ammonium nitrate as an initiator. The structural analysis of the graft copolymers was carried out by Fourier transform infrared and X-ray diffraction. The graft copolymers were also characterized by field emission scanning electron microscopy (FESEM). An additional peak at 1732 cm-1 which was attributed to the C=O of ester stretching vibration of poly(methyl methacrylate), appeared in the spectrum of grafted Agave cellulose. A slight decrease of crystallinity index upon grafting was found from 0.74 to 0.68 for cellulose and grafted Agave cellulose, respectively. Another evidence of grafting showed in the FESEM observation, where the surface of the grafted cellulose was found to be roughed than the raw one.

Rosli, Noor Afizah; Ahmad, Ishak; Abdullah, Ibrahim; Anuar, Farah Hannan

2013-11-01

433

Physical properties of agave cellulose graft polymethyl methacrylate  

International Nuclear Information System (INIS)

The grafting polymerization of methyl methacrylate and Agave cellulose was prepared and their structural analysis and morphology were investigated. The grafting reaction was carried out in an aqueous medium using ceric ammonium nitrate as an initiator. The structural analysis of the graft copolymers was carried out by Fourier transform infrared and X-ray diffraction. The graft copolymers were also characterized by field emission scanning electron microscopy (FESEM). An additional peak at 1732 cm?1 which was attributed to the C=O of ester stretching vibration of poly(methyl methacrylate), appeared in the spectrum of grafted Agave cellulose. A slight decrease of crystallinity index upon grafting was found from 0.74 to 0.68 for cellulose and grafted Agave cellulose, respectively. Another evidence of grafting showed in the FESEM observation, where the surface of the grafted cellulose was found to be roughed than the raw one

434

Radiation grafting of maleic anhydride onto polypropylene in suspension system  

Science.gov (United States)

This paper studies the grafting of maleic anhydride (MAH) onto polypropylene (PP) performed in suspension through co-irradiation in the absence of an initiator. The effect of radiation dose and MAH concentration on the graft degree of MAH onto PP was investigated. The graft degree and relative viscosity of grafted MAH were investigated by means of chemical titration and viscosity measurements. The results show that the co-irradiation in suspension systems can obviously cause the increase of the amount of grafted MAH, implying that the grafting reaction consists of chain scission and the grafting reaction of the produced macroradicals with MAH. The percentage of grafting of the product amounts to