WorldWideScience
1

Cine MRI of swallowing in patients with advanced oral or oropharyngeal carcinoma: a feasibility study.  

Science.gov (United States)

Treatment of oral and oropharyngeal cancer may cause dysphagia. Purpose is to examine whether cine magnetic resonance imaging (MRI) yields additional information compared to standard examination in the evaluation of posttreatment dysphagia and mobility of oral and oropharyngeal structures. Thirty-four cine MRIs were made in 23 patients with advanced oral and oropharyngeal cancer, consisting of an MR image every 800 ms during swallowing which is compared to videofluoroscopy and quality of life questionnaires. A scoring system was applied to assess mobility on cine MR and videofluoroscopy leading to a score ranging from 9 to 17. Cine MRI of the swallowing in a midsagittal plane visualized the tumor (if located in the same plane), important anatomic structures and surgical reconstructions. Posttreatment mobility on cine MRI and videofluoroscopy was significantly diminished compared to pretreatment, mean pretreatment cine MRI score was 10.8 and posttreatment 12.4 (p = 0.017). Impaired mobility on cine MRI was significantly correlated to more swallowing problems (Spearman's correlation coefficient 0.73, p = 0.04), on videofluoroscopy not. Cine MRI is a promising new technique as an adjunct to standard examinations for evaluation of swallowing in patients with oral and oropharyngeal cancer. Cine MRI directly visualizes the dynamics of swallowing and allows evaluation of pre- and posttreatment differences. Abnormal findings are significantly correlated with subjective swallowing complaints of patients. PMID:22218846

Kreeft, Anne Marijn; Rasch, Coen R N; Muller, Sara H; Pameijer, Frank A; Hallo, Eeke; Balm, Alfons J M

2012-06-01

2

Chest wall invasion by bronchogenic carcinoma. Evaluation with Cine-MRI  

Energy Technology Data Exchange (ETDEWEB)

With the view of examining possible chest wall invasion of bronchogenic carcinoma, Cine-MRI was performed on 22 such cases. These cases were suspected of having above chest wall invasion by CT and their histopathological findings were obtained in surgery. The judgment of the chest wall invasion by Cine-CT was made such that non-moving up and down of the tumor with respiration involves its invasion, moving of the tumor without any up-and-down movement suspects its invasion and moving up and down of the tumor with respiration involves no invasion. The chest wall invasion was observed in 5 of 7 cases of invasion judged by Cine-MRI. For 2 false-positive cases, the histopathological findings presumed that tumor cells disappeared from the chest wall invaded region as the result of preoperative chemotherapy. The above invasion was observed in 1 of 4 cases suspected of possible invasion. Correct diagnosis was formed of 11 cases judged invasion-free by Cine-MRI. The above results suggested Cine-MRI to be useful for diagnosis of chest wall invasion of bronchogenic carcinoma. (author).

Nawano, Shigeru; Murakami, Kohji; Ohnuma, Hiroshi; Iwata, Ryoko; Hayashi, Takayuki; Moriyama, Noriyuki; Nishiwaki, Yutaka; Nagai, Kanji [National Cancer Center, Kashiwa, Chiba (Japan). Hospital East

1996-01-01

3

Conventional and cine-MRI in patients with aneurysms of the abdominal aorta  

International Nuclear Information System (INIS)

We studied 40 patients with aneurysms of the abdominal aorta by MRI. These results were compared with those obtained by real-time sonography (n = 40), angiography (n = 32) and CT (n = 16). In 30 patients the imaging results were compared - as far as possible - with the operative findings. MRI proved more reliable, especially if compared with sonography, in evaluating renal or iliac artery involvement. Mural thrombi were detected more often (93%) by MRI than by CT (85%) or sonography (83%). Cine-MRI showed strong turbulences in 33%. Turbulences did not correlate with the size of the aneurysm. (orig.)

4

Cine MRI of the thorax in patients with pectus excavatum  

International Nuclear Information System (INIS)

Morphologic and dynamic assessment of respiratory chest kinetics was performed in patients with pectus excavatum deformity (PE) using dynamic MRI: cine MRI. Seven consecutive patients with PE (aged 20.3 years±4.0) and ten healthy volunteers of comparable age underwent real-time cine MRI of the chest during breathing on a 1.5 T MR scanner (Magnetom Sonata, Siemens Medical Systems, Erlangen, Germany) using a standard phased array body coil and a half-Fourier single-shot turbo spin echo sequence (HASTE) for dynamic imaging. During deep inspiration and expiration, single-shot sequences were performed in one slice level over 20 s at a frequency of 1 image/s covering the entire thoracic cage in three orientations. Morphology and chest kinetics in patients with PE were analyzed and compared with normal values, and typical patterns of chest kinetics were noted. Three different types of chest morphology in PE were identified: (1) the generally flattened thoracic cage, (2) the ''tilted'' sternum, and (3) the focally deepened sternum. Three patterns of motion correspond to these morphological types: (1) elevation of the sternum and the anterior thoracic wall, (2) angulated elevation of the parasternal rib cage with persistent deepening of the sternum resembling a ''wing beat'' movement, and (3) increased diaphragmatic movements with limited chest wall dynamics. Cine MRI is an adequate radiation-free diagnostic modality for the dynamic imaging of both chest morphology and chest aging of both chest morphology and chest wall kinetics in patients with PE. The pectus severity index can easily be determined and three typical movement patterns of chest wall kinetics identified. (orig.)

5

Comparison of standard, prone and cine MRI in the evaluation of tethered cord  

International Nuclear Information System (INIS)

Tethered cord syndrome (TCS) is defined by abnormal traction on the spinal cord that confines its movement. Surgical cord release usually stops neurological deterioration; therefore, early and accurate neuroradiological diagnosis is important. Supine MRI is the imaging modality of choice, but prone MRI and cine MRI can demonstrate cord movement. We compared the diagnostic accuracies of standard MRI, prone MRI and cine MRI in patients with clinical suspicion of TCS and evaluated inter-reader reliability for MR imaging. Children who underwent MRI for suspicion of TCS were retrospectively identified. Supine, prone and cine MRI studies were re-read by two pediatric neuroradiologists. Conus level, filum appearance and cord movement were documented. Thirteen of 49 children had tethered cord documented at surgery. Conus level had the highest diagnostic accuracy (sensitivity 69-77%, specificity 94%, positive predictive value 82-83%, negative predictive value 89-92%, correct diagnosis 88-90%) and highest between-reader concordance (98%). Prone and cine MRI did not add to the accuracy of the supine imaging. Conus level provides the highest diagnostic accuracy and inter-reader reliability in TCS. Until a larger series is evaluated, it remains questionable whether prone or cine MRI provides enough additional diagnostic information to warrant routine use. (orig.)

6

Cine MRI of the temporomandibular joint in comparison to static MRI and axiography  

International Nuclear Information System (INIS)

Purpose: To evaluate Cine MRI (cMRI) of the temporomandibular joint in comparison to static MRI (sMRI) and axiography. Materials and Methods: In a prospective study with 57 healthy volunteers as well as 33 patients after temporomandibular joint (TMJ) surgery or with severe joint dysfunction, we measured the mobility of both condyle and disc as well as the sagittal angle of condylar inclination with sMRI and cMRI. Measurements and image analysis were performed by a radiologist and a maxillofacial surgeon in consensus. The results of axiography served as standard of reference. Result: Concerning the assessment of the discoligamentous complex, sMRI was superior to cMRI in the patient-group (sensitivity sMRI 85%, cMRI 76%), while no significant difference was found in the volunteer-group (sensitivity sMRI 97.4%, cMRI 98.3%). The results of cMRI and sMRI showed a highly significant correlation with each other, as well as with the axiographic reference tracings (r=0.90). The average mobility of the disc and condyle was 6% and 10% higher in sMRI compared to cMRI (p=0.001) and showed a slightly higher variance (0.043 vs. 0.038). Concerning the condylar inclination angle, both MRI-procedures had the best correlation (r=0.94) with each other and axiography. Conclusion: Real-time MRI of the TMJ is comparable to axiography in its accuracy and is a useful adjunct to conventional static MRI. (orig.)

7

Self-gated cardiac Cine MRI of the rat on a clinical 3?T MRI system.  

Science.gov (United States)

The ability to perform small animal functional cardiac imaging on clinical MRI scanners may be of particular value in cases in which the availability of a dedicated high field animal MRI scanner is limited. Here, we propose radial MR cardiac imaging in the rat on a whole-body clinical 3?T scanner in combination with interspersed projection navigators for self-gating without any additional external triggering requirements for electrocardiogram (ECG) and respiration. Single navigator readouts were interspersed using the same TR and a high navigator frequency of 54?Hz into a radial golden-angle acquisition. The extracted navigator function was thresholded to exclude data for reconstruction from inhalation phases during the breathing cycle, enabling free breathing acquisition. To minimize flow artifacts in the dynamic cine images a center-out half echo radial acquisition scheme with ramp sampling was used. Navigator functions were derived from the corresponding projection navigator data from which both respiration and cardiac cycles were extracted. Self-gated cine acquisition resulted in high-quality cardiac images which were free of major artifacts with spatial resolution of up to 0.21?×?0.21?×?1.00?mm(3) and a contrast-to-noise ratio (CNR) of 21?±?3 between the myocardium and left ventricle. Self-gated golden ratio based radial acquisition successfully acquired cine images of the rat heart on a clinical MRI system without the need for dedicated animal ECG equipment. PMID:25417764

Krämer, Martin; Herrmann, Karl-Heinz; Biermann, Judith; Freiburger, Sebastian; Schwarzer, Michael; Reichenbach, Jürgen R

2015-02-01

8

SU-E-J-192: Verification of 4D-MRI Internal Target Volume Using Cine MRI  

International Nuclear Information System (INIS)

Purpose: To investigate the accuracy of 4D-MRI in determining the Internal Target Volume (ITV) used in radiation oncology treatment planning of liver cancers. Cine MRI is used as the standard baseline in establishing the feasibility and accuracy of 4D-MRI tumor motion within the liver. Methods: IRB approval was obtained for this retrospective study. Analysis was performed on MR images from four patients receiving external beam radiation therapy for liver cancer at our institution. Eligible patients received both Cine and 4D-MRI scans before treatment. Cine images were acquired sagittally in real time at a slice bisecting the tumor, while 4D images were acquired volumetrically. Cine MR DICOM headers were manipulated such that each respiratory frame was assigned a unique slice location. This approach permitted the treatment planning system (Eclipse, Varian Medical Systems) to recognize a complete respiratory cycle as a “volume”, where the gross tumor was contoured temporally. Software was developed to calculate the union of all frame contours in the structure set, resulting in the corresponding plane of the ITV projecting through the middle of the tumor, defined as the Internal Target Area (ITA). This was repeated for 4D-MRI, at the corresponding slice location, allowing a direct comparison of ITAs obtained from each modality. Results: Four patients have been analyzed. ITAs contoured from 4D-MRI correlate with contours from Cine MRI. The mean error of 4D values relative to Cine values is 7.67 +/? 2.55 %. No single ITA contoured from 4D-MRI demonstrated more than 10.5 % error compared to its Cine MRI counterpart. Conclusion: Motion management is a significant aspect of treatment planning within dynamic environments such as the liver, where diaphragmatic and cardiac activity influence plan accuracy. This small pilot study suggests that 4D-MRI based ITA measurements agree with Cine MRI based measurements, an important step towards clinical implementation. NIH 1R21CA165384-01A1

9

Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes  

DEFF Research Database (Denmark)

The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure. The proposed strategy relies on acquiring a pre-treatment 3D breath-hold scan, extracting a 3D target template and performing template matching between this 3D template and pairs of orthogonal 2D cine-MRI planes intersecting the target motion path. For a 60 s free-breathing series of orthogonal cine-MRI planes, we demonstrate that the method was capable of accurately tracking the respiration related 3D motion of the left kidney. Quantitative evaluation of the method using a dataset designed for this purpose revealed a translational error of 1.15 mm for a translation of 39.9 mm. We have demonstrated how interleaved acquired, orthogonal cine-MRI planes can be used foronline tracking of soft-tissue target volumes.

Bjerre, Troels; Crijns, Sjoerd

2013-01-01

10

Evaluation of pulmonary arterial morphology and function in cyanotic congenital heart disease by MRI and cine MRI  

International Nuclear Information System (INIS)

Pulmonary arterial anatomy was evaluated by magnetic resonance imaging (MRI), angiography and two-dimensional echocardiography in 20 patients with cyanotic heart disease associated with decreased pulmonary blood flow. Excellent correlation between MRI and angiographic estimates of pulmonary artery diameter was obtained (main pulmonary artery, r=0.87; right pulmonary artery, r=0.96; left pulmonary artery, r=0.95). However, echocardiography could not describe peripheral pulmonary arteries obviously, especially left pulmonary artery. In the assessment of peripheral pulmonary stenosis or obstruction, cine MRI was superior to echocardiography. We conclude that MRI and cine MRI will play an important role in the serial evaluation of pulmonary arterial morphology and function in patients with cyanotic congenital heart disease before and after surgical repair. (author)

11

Cine MRI of the thorax in patients with pectus excavatum; CINE-MRT des Thorax bei Patienten mit Pectus excavatum  

Energy Technology Data Exchange (ETDEWEB)

Morphologic and dynamic assessment of respiratory chest kinetics was performed in patients with pectus excavatum deformity (PE) using dynamic MRI: cine MRI. Seven consecutive patients with PE (aged 20.3 years{+-}4.0) and ten healthy volunteers of comparable age underwent real-time cine MRI of the chest during breathing on a 1.5 T MR scanner (Magnetom Sonata, Siemens Medical Systems, Erlangen, Germany) using a standard phased array body coil and a half-Fourier single-shot turbo spin echo sequence (HASTE) for dynamic imaging. During deep inspiration and expiration, single-shot sequences were performed in one slice level over 20 s at a frequency of 1 image/s covering the entire thoracic cage in three orientations. Morphology and chest kinetics in patients with PE were analyzed and compared with normal values, and typical patterns of chest kinetics were noted. Three different types of chest morphology in PE were identified: (1) the generally flattened thoracic cage, (2) the ''tilted'' sternum, and (3) the focally deepened sternum. Three patterns of motion correspond to these morphological types: (1) elevation of the sternum and the anterior thoracic wall, (2) angulated elevation of the parasternal rib cage with persistent deepening of the sternum resembling a ''wing beat'' movement, and (3) increased diaphragmatic movements with limited chest wall dynamics. Cine MRI is an adequate radiation-free diagnostic modality for the dynamic imaging of both chest morphology and chest wall kinetics in patients with PE. The pectus severity index can easily be determined and three typical movement patterns of chest wall kinetics identified. (orig.) [German] Morphologische und dynamische Darstellung typischer Bewegungsmuster der Atemmechanik bei Patienten mit Pectus excavatum (PE) mit dynamischer MRT: CINE-MRT. Sieben Patienten mit PE (Alter 20,3 Jahre {+-} 4,0) und 10 gesunde Probanden entsprechenden Alters wurden mit CINE-MRT des Thorax an einem 1,5-T-MRT (Magnetom Sonata, Siemens Medical Systems, Erlangen) untersucht. Bei Verwendung einer Phased-array-Koerperspule und einer Half-Fourier-single-shot-turbo-Spinechosequenz (HASTE) wurden bei tiefer, kontinuierlicher In- und Exspiration Einzelschichtmessungen in allen 3 Raumebenen mit einem Bild/s ueber die Dauer von 20 s angefertigt. Morphologie und Bewegungsmuster des Thorax wurden vergleichend analysiert, und dabei konnten typische Bewegungsabfolgen waehrend des Atemzyklus identifiziert werden. Es konnten 3 morphologische Formen der PE unterschieden werden: Der insgesamt abgeflachte Thorax, das ''gekippte, schraeg gestellte'' Sternum und das ''punktuell eingesunkene'' Sternum. Diesen entsprechen 3 Bewegungsmuster der Atemmechanik des Thorax bei PE: (1) gleichmaessiges Anheben von Sternum und vorderer Brustwand, (2) beidseitig abgewinkeltes Anheben der vorderen Brustwand bei konstant eingesunkenem Sternum (''Fluegelschlagdynamik'') und (3) betontes Absenken des Zwerchfells bei geringer Thoraxexkursion. CINE-MRT ist eine einfache und strahlenfreie Methode zur dynamischen Darstellung der Thoraxatemmechanik bei PE. Individuelle Auspraegung und Schweregrad der Deformitaet koennen zuverlaessig erfasst werden, wobei typische Bewegungsmuster erkennbar sind. (orig.)

Herrmann, K.A.; Zech, C.J.; Schoenberg, S.O.; Reiser, M.F. [Klinikum Grosshadern der Ludwig-Maximilians-Universitaet, Institut fuer Klinische Radiologie, Muenchen (Germany); Strauss, T.; Hatz, R. [Klinikum Grosshadern der Ludwig-Maximilians-Universitaet Muenchen (Germany). Klinik und Poliklinik fuer Chirurgie

2006-04-15

12

Three-dimensional cine MRI in free-breathing infants and children with congenital heart disease  

Energy Technology Data Exchange (ETDEWEB)

Patients with congenital heart disease frequently have complex cardiac and vascular malformations requiring detailed non-invasive diagnostic evaluation including functional parameters. To evaluate the morphological and functional information provided by a novel 3-D cine steady-state free-precession (SSFP) sequence. Twenty consecutive children (mean age 2.2 years, nine boys) were examined using a 1.5-T MR system including 2-D cine gradient-recalled-echo sequences, static 3-D SSFP and 3-D cine SSFP sequences. Measurement of ventricular structures and volumes showed close agreement between the 3-D cine SSFP sequence and the 2-D cine gradient-recalled-echo and static 3-D SSFP sequences (left ventricular volumes mean difference 1.0-1.9 ml and 8.8-11.4%, respectively; right ventricular volumes 1.7-2.1 ml and 9.9-16.9%, respectively). No systematic bias was observed. 3-D cine MRI provides anatomic as well as functional information with sufficient spatial and temporal resolution in free-breathing infants with congenital heart disease. (orig.)

Seeger, Achim; Fenchel, Michael C.; Kramer, Ulrich; Bretschneider, Christiane; Doering, Joerg; Claussen, Claus D.; Miller, Stephan [University of Tuebingen (Germany). Department of Diagnostic and Interventional Radiology; Greil, Gerald F. [St. Thomas Hospital, Division of Imaging Sciences, King' s College London (United Kingdom); Martirosian, Petros [University of Tuebingen, Section of Experimental Radiology, Tuebingen (Germany); Sieverding, Ludger [University of Tuebingen, Department of Pediatric Cardiology, Tuebingen (Germany)

2009-12-15

13

MRI Findings in Neuroferritinopathy  

OpenAIRE

Neuroferritinopathy is a neurodegenerative disease which demonstrates brain iron accumulation caused by the mutations in the ferritin light chain gene. On brain MRI in neuroferritinopathy, iron deposits are observed as low-intensity areas on T2WI and as signal loss on T2?WI. On T2WI, hyperintense abnormalities reflecting tissue edema and gliosis are also seen. Another characteristic finding is the presence of symmetrical cystic changes in the basal ganglia, which are s...

Emiko Ohta; Yoshihisa Takiyama

2011-01-01

14

MRI findings in neuroferritinopathy.  

Science.gov (United States)

Neuroferritinopathy is a neurodegenerative disease which demonstrates brain iron accumulation caused by the mutations in the ferritin light chain gene. On brain MRI in neuroferritinopathy, iron deposits are observed as low-intensity areas on T2WI and as signal loss on T2(?)WI. On T2WI, hyperintense abnormalities reflecting tissue edema and gliosis are also seen. Another characteristic finding is the presence of symmetrical cystic changes in the basal ganglia, which are seen in the advanced stages of this disorder. Atrophy is sometimes noted in the cerebellar and cerebral cortices. The variety in the MRI findings is specific to neuroferritinopathy. Based on observations of an excessive iron content in patients with chronic neurologic disorders, such as Parkinson disease and Alzheimer disease, the presence of excess iron is therefore recognized as a major risk factor for neurodegenerative diseases. The future development of multimodal and advanced MRI techniques is thus expected to play an important role in accurately measuring the brain iron content and thereby further elucidating the neurodegenerative process. PMID:21808735

Ohta, Emiko; Takiyama, Yoshihisa

2012-01-01

15

MRI finding of hemangioblastomas  

International Nuclear Information System (INIS)

The purpose of this study is to evaluate the findings of magnetic resonance imaging (MRI) of posterior fossa hemanangioblastoma and usefulness of contrast enhancement with Gd-DTPA. Seven patients with posterior fossa hemangioblastoma were studied with both pre- and post-enhanced MRI. The MR images were reviewed regarding the location, size, signal intensities of cysts and mural nodules, and their contrast enhancement pattern. Five tumors were located in cerebellar hemisphere, one in vermis, and one in posterior part of medulla. One patient with von Hippel-Lindau disease had a medullary hemangioblastoma with multiple pancreatic cysts. In 6 cases, the major portion of the tumor was cysts and had small mulkal nodules. The solid portion was relatively lange in one cases, cemprising half of the tumor cysts were oval shaped and their sized were 3-6.7 cm in diameter. In five cases(71%), septations were noted within the cysts. Cysts were isointense or slightly hyperintense on T1-weighted image and hyperintense on T2- weighted image compared with cerebrospinal fluid. Mural nodules were oval or rounded radiotherapy had better prognosis than those treated with radiotherapy alwas 0.5-2.5 cm in diameter. Mural nodules were isointense to gray matter. They were detected in five cases on T1-weighted images and one case on T2-weighted images. In two cases, vascular signal void area was noted in mural nodules. On contrast-enhanced T1-weighted images, all mural nodules were intensely enmages, all mural nodules were intensely enhanced. MRI provide to be a good diagnostic method to detect and characterize posterior fossa hemangioblastoma. The most common finding is Cystic posterior fossa lesion with enhancing mural nodule. Contrast enhancement is essential for specific diagnosis

16

MRI finding of hemangioblastomas  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study is to evaluate the findings of magnetic resonance imaging (MRI) of posterior fossa hemanangioblastoma and usefulness of contrast enhancement with Gd-DTPA. Seven patients with posterior fossa hemangioblastoma were studied with both pre- and post-enhanced MRI. The MR images were reviewed regarding the location, size, signal intensities of cysts and mural nodules, and their contrast enhancement pattern. Five tumors were located in cerebellar hemisphere, one in vermis, and one in posterior part of medulla. One patient with von Hippel-Lindau disease had a medullary hemangioblastoma with multiple pancreatic cysts. In 6 cases, the major portion of the tumor was cysts and had small mulkal nodules. The solid portion was relatively lange in one cases, cemprising half of the tumor cysts were oval shaped and their sized were 3-6.7 cm in diameter. In five cases(71%), septations were noted within the cysts. Cysts were isointense or slightly hyperintense on T1-weighted image and hyperintense on T2- weighted image compared with cerebrospinal fluid. Mural nodules were oval or rounded radiotherapy had better prognosis than those treated with radiotherapy alwas 0.5-2.5 cm in diameter. Mural nodules were isointense to gray matter. They were detected in five cases on T1-weighted images and one case on T2-weighted images. In two cases, vascular signal void area was noted in mural nodules. On contrast-enhanced T1-weighted images, all mural nodules were intensely enhanced. MRI provide to be a good diagnostic method to detect and characterize posterior fossa hemangioblastoma. The most common finding is Cystic posterior fossa lesion with enhancing mural nodule. Contrast enhancement is essential for specific diagnosis.

Park, Seung Cheol; Oh, Min Cheol; Chung, Hwan Hoon; Seol, Hye Young; Lee, Nam Joon; Kim, Jung Hyuk [Korea University College of Medicine, Seoul (Korea, Republic of)

1994-05-15

17

Evaluation of potential internal target volume of liver tumors using cine-MRI  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Four-dimensional computed tomography (4DCT) is widely used for evaluating moving tumors, including lung and liver cancers. For patients with unstable respiration, however, the 4DCT may not visualize tumor motion properly. High-speed magnetic resonance imaging (MRI) sequences (cine-MRI) permit direct visualization of respiratory motion of liver tumors without considering radiation dose exposure to patients. Here, the authors demonstrated a technique for evaluating internal target volume (ITV) with consideration of respiratory variation using cine-MRI. Methods: The authors retrospectively evaluated six patients who received stereotactic body radiotherapy (SBRT) to hepatocellular carcinoma. Before acquiring planning CT, sagittal and coronal cine-MRI images were acquired for 30 s with a frame rate of 2 frames/s. The patient immobilization was conducted under the same condition as SBRT. Planning CT images were then acquired within 15 min from cine-MRI image acquisitions, followed by a 4DCT scan. To calculate tumor motion, the motion vectors between two continuous frames of cine-MRI images were calculated for each frame using the pyramidal Lucas–Kanade method. The target contour was delineated on one frame, and each vertex of the contour was shifted and copied onto the following frame using neighboring motion vectors. 3D trajectory data were generated with the centroid of the contours on sagittal and coronal images. To evaluate the accuracy of the tracking method, the motion of clearly visible blood vessel was analyzed with the motion tracking and manual detection techniques. The target volume delineated on the 50% (end-exhale) phase of 4DCT was translated with the trajectory data, and the distribution of the occupancy probability of target volume was calculated as potential ITV (ITV {sub Potential}). The concordance between ITV {sub Potential} and ITV estimated with 4DCT (ITV {sub 4DCT}) was evaluated using the Dice’s similarity coefficient (DSC). Results: The distance between blood vessel positions determined with motion tracking and manual detection was analyzed. The mean and SD of the distance were less than 0.80 and 0.52 mm, respectively. The maximum ranges of tumor motion on cine-MRI were 2.4 ± 1.4 mm (range, 1.0–5.0 mm), 4.4 ± 3.3 mm (range, 0.8–9.4 mm), and 14.7 ± 5.9 mm (range, 7.4–23.4 mm) in lateral, anterior–posterior, and superior–inferior directions, respectively. The ranges in the superior–inferior direction were larger than those estimated with 4DCT images for all patients. The volume of ITV {sub Potential} was 160.3% ± 13.5% (range, 142.0%–179.2%) of the ITV {sub 4DCT}. The maximum DSC values were observed when the cutoff value of 24.7% ± 4.0% (range, 20%–29%) was applied. Conclusions: The authors demonstrated a novel method of calculating 3D motion and ITV {sub Potential} of liver cancer using orthogonal cine-MRI. Their method achieved accurate calculation of the respiratory motion of moving structures. Individual evaluation of the ITV {sub Potential} will aid in improving respiration management and treatment planning.

Akino, Yuichi, E-mail: akino@radonc.med.osaka-u.ac.jp [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka 5650871, Japan and Miyakojima IGRT Clinic, Miyakojima-ku, Osaka 5340021 (Japan); Oh, Ryoong-Jin; Masai, Norihisa; Shiomi, Hiroya; Inoue, Toshihiko [Miyakojima IGRT Clinic, Miyakojima-ku, Osaka 5340021 (Japan)

2014-11-01

18

Evaluation of potential internal target volume of liver tumors using cine-MRI  

International Nuclear Information System (INIS)

Purpose: Four-dimensional computed tomography (4DCT) is widely used for evaluating moving tumors, including lung and liver cancers. For patients with unstable respiration, however, the 4DCT may not visualize tumor motion properly. High-speed magnetic resonance imaging (MRI) sequences (cine-MRI) permit direct visualization of respiratory motion of liver tumors without considering radiation dose exposure to patients. Here, the authors demonstrated a technique for evaluating internal target volume (ITV) with consideration of respiratory variation using cine-MRI. Methods: The authors retrospectively evaluated six patients who received stereotactic body radiotherapy (SBRT) to hepatocellular carcinoma. Before acquiring planning CT, sagittal and coronal cine-MRI images were acquired for 30 s with a frame rate of 2 frames/s. The patient immobilization was conducted under the same condition as SBRT. Planning CT images were then acquired within 15 min from cine-MRI image acquisitions, followed by a 4DCT scan. To calculate tumor motion, the motion vectors between two continuous frames of cine-MRI images were calculated for each frame using the pyramidal Lucas–Kanade method. The target contour was delineated on one frame, and each vertex of the contour was shifted and copied onto the following frame using neighboring motion vectors. 3D trajectory data were generated with the centroid of the contours on sagittal and coronal images. To evaluate the accuracy of the tracking method, the motion of clearly visible blood vessel was analyzed with the motion tracking and manual detection techniques. The target volume delineated on the 50% (end-exhale) phase of 4DCT was translated with the trajectory data, and the distribution of the occupancy probability of target volume was calculated as potential ITV (ITV Potential). The concordance between ITV Potential and ITV estimated with 4DCT (ITV 4DCT) was evaluated using the Dice’s similarity coefficient (DSC). Results: The distance between blood vessel positions determined with motion tracking and manual detection was analyzed. The mean and SD of the distance were less than 0.80 and 0.52 mm, respectively. The maximum ranges of tumor motion on cine-MRI were 2.4 ± 1.4 mm (range, 1.0–5.0 mm), 4.4 ± 3.3 mm (range, 0.8–9.4 mm), and 14.7 ± 5.9 mm (range, 7.4–23.4 mm) in lateral, anterior–posterior, and superior–inferior directions, respectively. The ranges in the superior–inferior direction were larger than those estimated with 4DCT images for all patients. The volume of ITV Potential was 160.3% ± 13.5% (range, 142.0%–179.2%) of the ITV 4DCT. The maximum DSC values were observed when the cutoff value of 24.7% ± 4.0% (range, 20%–29%) was applied. Conclusions: The authors demonstrated a novel method of calculating 3D motion and ITV Potential of liver cancer using orthogonal cine-MRI. Their method achieved accurate calculation of the respiratory motion of moving structures. Individual evaluation of the ITV Potential will aid in improving respiration management and treatment planning

19

Wireless Self-Gated Multiple-Mouse Cardiac Cine MRI  

OpenAIRE

Despite the excellent image-contrast capability of MRI and the ability to synchronize MRI with the murine cardiac cycle, this technique is underused for assessing mouse models of cardiovascular disease because of its perceived cost and complexity. This perception stems, in part, from complications associated with the placement and adjustment of electrocardiographic leads that may interact with gradient pulses and the relatively long acquisition times required with traditional gating schemes. ...

Esparza-coss, Emilio; Ramirez, Marc S.; Bankson, James A.

2008-01-01

20

Whole-heart cine MRI using real-time respiratory self-gating.  

Science.gov (United States)

Two-dimensional (2D) breath-hold cine MRI is used to assess cardiac anatomy and function. However, this technique requires cooperation from the patient, and in some cases the scan planning is complicated. Isotropic nonangulated three-dimensional (3D) cardiac MR can overcome some of these problems because it requires minimal planning and can be reformatted in any plane. However, current methods, even those that use undersampling techniques, involve breath-holding for periods that are too long for many patients. Free-breathing respiratory gating sequences represent a possible solution for realizing 3D cine imaging. A real-time respiratory self-gating technique for whole-heart cine MRI is presented. The technique enables assessment of cardiac anatomy and function with minimum planning or patient cooperation. Nonangulated isotropic 3D data were acquired from five healthy volunteers and then reformatted into 2D clinical views. The respiratory self-gating technique is shown to improve image quality in free-breathing scanning. In addition, ventricular volumetric data obtained using the 3D approach were comparable to those acquired with the conventional multislice 2D approach. PMID:17326164

Uribe, Sergio; Muthurangu, Vivek; Boubertakh, Redha; Schaeffter, Tobias; Razavi, Reza; Hill, Derek L G; Hansen, Michael S

2007-03-01

21

Stress cine MRI for detection of coronary artery disease; Stress-Cine-MRT zur Primaeridagnostik der koronaren Herzkrankheit  

Energy Technology Data Exchange (ETDEWEB)

Stress testing is the cornerstone in the diagnosis of patients with suspected coronary artery disease (CAD). Stress echocardiography has become a well-established modality for the detection of ischemia-induced wall motion abnormalities. However, display and reliable interpretation of stress echocardiography studies are user-dependent, the test reproducibility is low, and 10 to 15% of patients yield suboptimal or non-diagnostic images. Due to its high spatial and contrast resolution, MRI is known to permit an accurate determination of left ventricular function and wall thickness at rest. Early stress MRI studies provided promising results with respect to the detection of CAD. However, the clinical impact was limited due to long imaging time and problematic patient monitoring in the MRI environment. Recent technical improvements - namely ultrafast MR image acquisition - led to a significant reduction of imaging time and improved patient safety. Stress can be induced by physical exercise or pharmacologically by administration of a beta{sub 1}-agonist (dobutamine) or vasodilatator (dipyridamole and adenosine). The best developed and most promising stress MRI technique is a high-dose dobutamine/atropine stress protocol (10, 20, 30, 40 {mu}g/kg/min; optionally 0.25-mg fractions of atropine up to maximal dose 1 mg). Severe complications (myocardial infarction, ventricular fibrillation and sustained tachycardia, cardiogenic shock) may be expected in 0.25% of patients. Currently, data of three high-dose dobutamine stress MRI studies are available, revealing a good sensitivity (83 - 87%) and specificity (83 - 86%) in the assessment of CAD. The direct comparison between echocardiography and MRI for the detection of stress-induced wall motion abnormalities yielded better results for dobutamine-MRI in terms of sensitivity (86.2% vs. 74.3%; p < 0.05) and specificity (85.7% vs. 69.8% p < 0.05) as compared to dobutamine stress echocardiography. The superior results of MRI can mainly be explained by the better image quality with sharp delineation of the endocardial and epicardial borders. Currently, stress MRI is already a realistic clinical alternative for the non-invasive assessment of CAD in patients with impaired image quality in echocardiography. (orig.) [German] Belastungsuntersuchungen sind einer der wesentlichen Pfeiler der nicht-invasiven Diagnostik der koronaren Herzkrankheit (KHK). Die Stress-Cine-Magnetresonanztomographie (Stress-MRT) beruht wie die Stressechokardiographie auf dem direkten Nachweis ischaemieinduzierter Wandbewegungsstoerungen. Ihr Einsatz bei kardialen Belastungsuntersuchungen wurde bisher vor allem durch die langen Untersuchungszeiten und die limitierten Ueberwachungsmoeglichkeiten der Patienten eingeschraenkt. Erst seit kurzem wurden durch technische Weiterentwicklungen (insbesondere ultraschnelle k-Raum-segmentierte Sequenzen) die wesentlichen Rahmenbedingungen fuer eine klinisch praktikable kardiale MRT-Belastungsdiagnostik geschaffen. Als Stress-Induktoren koennen physikalische (Fahrradergometrie) und pharmakologische Belastungsverfahren ({beta}{sub 1}-Mimetika [Dobutamin] oder Vasodilatatoren [Dipyridamol, Adenosin]) eingesetzt werden. Insbesondere seit der Etablierung von Hochdosis-Protokollen mit fakultativer Atropingabe wird die Belastung mit Dobutamin bei der Stress-MRT zum Nachweis einer KHK (Sensitivitaet: 83 - 87%; Spezifitaet: 83 - 86%) von den meisten Arbeitsgruppen favorisiert. Schwerere Komplikationen treten in 0,25% der Faelle auf. Im direkten Vergleich zeigte sich die Dobutamin-Stress-MRT aufgrund der besseren Bildqualitaet der Dobutamin-Stressechokardiographie ueberlegen (Sensitivitaet: 86,2% vs. 74,3%, p < 0,05; Spezifitaet: 85,7% vs. 69,8%, p < 0,05). Die Stress-MRT ist bereits zum jetzigen Zeitpunkt eine realistische - in der Routinediagnostik anwendbare - Alternative zur Stressechokardiographie. Vom Einsatz der Stress-MRT profitieren zur Zeit v.a. Patienten, bei denen aufgrund grundsaetzlich schlechter Schallbarkeit mit hoher Wahrscheinlichkeit von nicht oder nur eingeschra

Sommer, T.; Hofer, U.; Schild, H. [Bonn Univ. (Germany). Radiologische Klinik; Omran, H. [Medizinische Universitaetsklinik II Bonn (Germany)

2002-05-01

22

Implementation of compressive sensing for preclinical cine-MRI  

Science.gov (United States)

This paper presents a practical implementation of Compressive Sensing (CS) for a preclinical MRI machine to acquire randomly undersampled k-space data in cardiac function imaging applications. First, random undersampling masks were generated based on Gaussian, Cauchy, wrapped Cauchy and von Mises probability distribution functions by the inverse transform method. The best masks for undersampling ratios of 0.3, 0.4 and 0.5 were chosen for animal experimentation, and were programmed into a Bruker Avance III BioSpec 7.0T MRI system through method programming in ParaVision. Three undersampled mouse heart datasets were obtained using a fast low angle shot (FLASH) sequence, along with a control undersampled phantom dataset. ECG and respiratory gating was used to obtain high quality images. After CS reconstructions were applied to all acquired data, resulting images were quantitatively analyzed using the performance metrics of reconstruction error and Structural Similarity Index (SSIM). The comparative analysis indicated that CS reconstructed images from MRI machine undersampled data were indeed comparable to CS reconstructed images from retrospective undersampled data, and that CS techniques are practical in a preclinical setting. The implementation achieved 2 to 4 times acceleration for image acquisition and satisfactory quality of image reconstruction.

Tan, Elliot; Yang, Ming; Ma, Lixin; Zheng, Yahong Rosa

2014-03-01

23

MRI findings in Kallmann syndrome  

OpenAIRE

Kallmann syndrome (KS) is a neuronal migration disorder characterised by hypogonadotrophic hypogonadism and anosmia or hyposmia. Five patients with clinical findings suggestive of KS were evaluated with MRI. All patients had abnormalities of olfactory system. Olfactory bulbs were absent in all patients. Olfactory sulci were absent in 3 patients and hypoplastic in 2 patients. Anterior pituitary was hypoplastic in two patients. The MRI findings in KS are characteristic and MRI is a useful adjun...

Madan R; Sawlani Vijay; Gupta Sushil; Phadke R

2004-01-01

24

MRI findings in Kallmann syndrome  

Directory of Open Access Journals (Sweden)

Full Text Available Kallmann syndrome (KS is a neuronal migration disorder characterised by hypogonadotrophic hypogonadism and anosmia or hyposmia. Five patients with clinical findings suggestive of KS were evaluated with MRI. All patients had abnormalities of olfactory system. Olfactory bulbs were absent in all patients. Olfactory sulci were absent in 3 patients and hypoplastic in 2 patients. Anterior pituitary was hypoplastic in two patients. The MRI findings in KS are characteristic and MRI is a useful adjunct to the diagnosis of KS.

Madan R

2004-10-01

25

Cine MRI for quantifying regurgitant lesions using a volume method  

International Nuclear Information System (INIS)

We have examined 46 patients with angiographically confirmed regurgitant lesions (26 mitral insufficiency, 20 aortic insufficiency) using a 0.5 Tesla magnet. In each patient, mulit-plane and multi-phase spin-echo sequences were obtained in a plane angled in the sagittal and coronal direction in the long axis of the heart; left and right ventricular volumes, ejection fractions and regurgitation fractions were calculated. In addition, a blood-flow sensitive gradient echo sequence was obtained in order to determine the direction and extent of the regurgitant jet. The data was compared with the results of angiography and echo-cardiography. By means of the gradient echo technique, MRI was able to show the regurgitant jet in every patient. There was a linear correlation between volumes determined by MRI and angiography. The best agreement was found for left ventricular contraction volume (R = 0.82, p is <0.0001). Comparison of the non-invasive and angiographic method showed a linear correlation for AI patients of R = 0.91 (p is <0.0001), which is somewhat better than for patients with MI (R = 0.84, p <0.001). Seme-quantitative grading of MI with a gradient echo technique showed a linear correlation with angiography of R = 0.73 (p <0.001), for AI there was agreement between both methods in 72% of cases. A comparison between MRI and colour Doppler sonography showed only moderately good correlation R = 0.69 (p<0.01). (orig.)

26

Hippocampal malrotation: MRI findings  

International Nuclear Information System (INIS)

Purpose: To demonstrate the common features of hippocampus malrotation in patients with epilepsy by volumetric and high-resolution MRI. Material and methods: MRI study was performed in 5 patients (2 females and 3 males) ages ranged between 6-41 years (average: 25 years), all of them with epilepsy diagnosis. MRI was performed with a 1.5 T (GE Signa). The epilepsy protocol include sagittal T1, axial T1 and T2, coronal FLAIR, coronal T2 (high-resolution) and volumetric 3D SPGR IR 1.5 mm thick sequences. Results: The common features found in all patients were: a) Incomplete inversion and round configuration of the hippocampus; b) Unilateral affectation; c) Variable affectation of the hippocampus; d) Normal signal intensity; e) Modification of the inner structure of the hippocampus; f) Abnormal angularity of the collateral sulcus; g) Abnormal position and size of the fornix; h) Normal size of the temporal lobe; and i) Enlargement of the temporal horn with particular configuration. Conclusion: Hippocampus malrotation is a malformation that should be included in the differential diagnosis of the epilepsy patients. MRI provides accurate information for the diagnosis. (author)

27

Cine-MRI tagging for assessment of ventricular wall motion in patients under maintenance hemodialysis  

International Nuclear Information System (INIS)

We evaluated the ventricular wall shortening velocity of patients with volume overload using cine-MRI tagging. The subjects were 12 healthy volunteers and 10 patients under maintenance hemodialysis. Three linear tags (basal, mid-ventricular, and apical) were set up in the 4-chamber view and ? distance/Ejection time (?d/ET) was calculated before and after hemodialysis. Before hemodialysis, ?d/ET was significantly greater at the basal level than after hemodialysis (right ventricular wall : 64.7±14.3 vs 59.1±15.4 mm/s, P<0.05, interventricular septum : 36.3±6.9 vs 32.4±7.6 mm/s, P<0.05, left ventricular free wall : 40.5±6.8 vs 36.1±8.2 mm/s, P<0.05). Thus, volume overload increased ?d/ET of the normal heart. We concluded that cine-MRI tagging could quantitatively evaluate right and left ventricular wall motion. (author)

28

Tissue-Point Motion Tracking in the Tongue from Cine MRI and Tagged MRI  

Science.gov (United States)

Purpose: Accurate tissue motion tracking within the tongue can help professionals diagnose and treat vocal tract--related disorders, evaluate speech quality before and after surgery, and conduct various scientific studies. The authors compared tissue tracking results from 4 widely used deformable registration (DR) methods applied to cine magnetic…

Woo, Jonghye; Stone, Maureen; Suo, Yuanming; Murano, Emi Z.; Prince, Jerry L.

2014-01-01

29

CSF dynamics in the patients with syringomyelia associated with Chiari's malformation; Quantitative analysis on cine MRI  

Energy Technology Data Exchange (ETDEWEB)

In a series of 12 patients with syringomyelia associated with Chiari's malformation, the authors quantitatively analyzed cerebrospinal fluid (CSF) dynamics in the subarachnoid space of the cranio-spinal junction, using cine MRI combined with pre-saturation method. In most of subjects, cine MRI revealed (1) decreased or increased maximum velocity of CSF in the caudal direction and (2) disturbed CSF motion in the caudal direction (delayed % cardiac cycle) in the craniospinal junction, strongly suggesting disturbed CSF dynamics in the craniospinal junction because of the tonsilar herniation. Of 12 subjects, 8 patients underwent formen magnum decompression and 4 underwent syringo-subarachnoid shunt (SS shunt). In the patients who showed marked callapse of syrinx after foramen magnum decompression, follow-up cine MRI revealed the normalization of % cardiac cycle, representing postoperative improvement of CSF dynamics in the craniospinal function. On the other hand, % cardiac cycle did not improve significantly in the patients who did not show marked collapse of the syrinx or suffered from meningitis after surgery. Significant changes were not observed in the patients who underwent SS shunt. In summary, these results suggested that cine MRI combined with pre-saturation method could detect the pathophysiological changes and evaluate the efficacy of the surgery, especially foramen magnum decompression, in the patients with syringomyelia associated with Chiari's malformation. (author).

Kuroda, Satoshi; Matsuzawa, Hitoshi; Iwasaki, Yoshinobu; Hida, Kazutoshi; Imamura, Hiroyuki; Abe, Hiroshi (Hokkaido Univ., Sapporo (Japan). School of Medicine); Saito, Hisatoshi

1994-01-01

30

MRI findings in Hirayama disease  

Directory of Open Access Journals (Sweden)

Full Text Available The objective of the study was to study the magnetic resonance imaging (MRI features of Hirayama disease on a 3 Tesla MRI scanner. Nine patients with clinically suspected Hirayama disease were evaluated with neutral position, flexion, contrast-enhanced MRI and fast imaging employing steady-state acquisition (FIESTA sequences. The spectrum of MRI features was evaluated and correlated with the clinical and electromyography findings. MRI findings of localized lower cervical cord atrophy (C5-C7, abnormal curvature, asymmetric cord flattening, loss of attachment of the dorsal dural sac and subjacent laminae in the neutral position, anterior displacement of the dorsal dura on flexion and a prominent epidural space were revealed in all patients on conventional MRI as well as with the dynamic 3D-FIESTA sequence. Intramedullary hyperintensity was seen in four patients on conventional MRI and on the 3D-FIESTA sequence. Flow voids were seen in four patients on conventional MRI sequences and in all patients with the 3D-FIESTA sequence. Contrast enhancement of the epidural component was noted in all the five patients with thoracic extensions. The time taken for conventional and contrast-enhanced MRI was about 30-40 min, while that for the 3D-FIESTA sequence was 6 min. Neutral and flexion position MRI and the 3D-FIESTA sequence compliment each other in displaying the spectrum of findings in Hirayama disease. A flexion study should form an essential part of the screening protocol in patients with suspected Hirayama disease. Newer sequences such as the 3D-FIESTA may help in reducing imaging time and obviating the need for contrast.

Raval Monali

2010-01-01

31

Rabies, encephalomyelitis: MRI findings  

International Nuclear Information System (INIS)

The authors present a 14 year old patient who started with walking and swallowing difficulty; followed by fever, abdominal and lower back pain. Mechanical breathing difficulties required a respiratory mechanic assistance. The diagnosis of Guillain-Barre syndrome was thought at first. Since the patient have had previous contact with a bat two months before the symptoms began, this suggested rabies as the main diagnosis, which was later confirmed by hair-bulb, cornea, oral mucosa and salival immunofluorescence. The brain and spinal cord MRI showed focal lesions in T2 and FLAIR sequences, compatible with encephalomyelitis. (author)

32

Brain venous pathologies: MRI findings  

International Nuclear Information System (INIS)

Purpose: To describe MRI findings of the different brain venous pathologies. Material and Methods: Between January 2002 and March 2004, 18 patients were studied 10 males and 8 females between 6 and 63 years old; with different brain venous pathologies. In all cases brain MRI were performed including morphological sequences with and without gadolinium injection and angiographic venous sequences. Results: 10 venous occlusions were found, 6 venous angiomas, and 2 presented varices secondary to arteriovenous dural fistula. Conclusion: Brain venous pathologies can appear in many different clinical contexts, with different prognosis and treatment. In all the cases brain MRI was the best imaging study to disclose typical morphologic abnormalities. (author)

33

Comparison of delayed enhanced cine MRI, single photon emission computed tomography and echocardiography for the detection of viable myocardium  

International Nuclear Information System (INIS)

Objective: To evaluate the accuracy of delayed enhanced cardiac MRI(DE-MRI), nitrate stress 99Tcm-MIBI imaging (N-SPECT) and low-dose dobutamine stress echocardiography (LDDSE) for the detection of viable myocardium. Methods: Cardiac rest cine MRI(cine-MRI), DE-URI, N-SPECT and LDDSE were performed in 32 patients within one week after onset of acute myocardial infarction and undertaking percutaneous coronary intervention (PCI) thereafter. Second cine-MRI was performed 6- 11 months after PCI. A 16-segment model was adopted for the image analysis. Wall motion improvement after PCI was considered as a myocardial viability. The sensitivity, specificity and accuracy of three methods for the detection of viable segments were compared dy t and ?2 test. Results: The sensitivity, specificity and accuracy of DE-MRI were 76.7% (79/103), 83.8% (88/105)and 80.3% (167/208), respectively. The sensitivity, specificity and accuracy of N-SPECT were 75.9% (82/108), 65.2% (60/92) and 71.0% (142/200), respectively. The specificity and accuracy of N-SPECT were significantly lower than that of DE- MRI(P<0.01). The sensitivity, specificity and accuracy of LDDSE were 70.1% (47/67), 70.4% (50/71) and 70. 3% (97/138), respectively. The sensitivity of LDDSE was comparable to that of DE-MRI and the specificity and accuracy of LDDSE were significantly lower than that of DE-MRI (P<0.05). Conclusion: DE-MRI with high specificity and accuracy, potentially, is a valuaity and accuracy, potentially, is a valuable imaging method for the detection of viable myocardium. (authors)

34

MRI findings of orbital mass  

International Nuclear Information System (INIS)

A total of 41 cases (17 pseudotumor, 11 lymphoma, 4 cavernous hemangioma, and 9 others) with a orbital mass (es), who underwent MRI, are the basis of this study. The 14 MRI findings (size, shape, signal intensity, etc.) were retrospectively analyzed. Subjective rating score of irregular undulation, homogeneity of signal intensity (SI) on T1WI and SI on (fat-sat) T2WI of cavernous hemangioma was significantly higher than that of pseudotumor. Subjective rating score of irregular undulation, SI on (fat-sat) T2WI and homogeneity of SI on (fat-sat) T2WI of cavernous hemangioma was significantly higher than that of lymphoma. Subjective rating score of lymphoma was significantly higher than that of pseudotumor. There was no significant difference in age, sex and subjective rating score of 9 MRI findings (size, shape, etc). (author)

35

Internal margin assessment using cine MRI analysis of deglutition in head and neck cancer radiotherapy  

International Nuclear Information System (INIS)

Purpose: Intensity-modulated radiation therapy (IMRT) is a promising treatment modality for patients with head and neck cancer (HNC). The dose distributions from IMRT are static and, thus, are unable to account for variations and/or uncertainties in the relationship between the patient (region being treated) and the beam. Organ motion comprises one such source of this uncertainty, introduced by physiological variation in the position, size, and shape of organs during treatment. In the head and neck, the predominant source of this variation arises from deglutition (swallowing). The purpose of this study was to investigate whether cinematographic MRI (cine MRI) could be used to determine asymmetric (nonuniform) internal margin (IM) components of tumor planning target volumes based on the actual deglutition-induced tumor displacement. Methods: Five head and neck cancer patients were set up in treatment position on a 3 T MRI scanner. Two time series of single-slice, sagittal, cine images were acquired using a 2D FLASH sequence. The first time series was a 12.8 min scan designed to capture the frequency and duration of deglutition in the treatment position. The second time series was a short, 15 s scan designed to capture the displacement of deglutition in the treatment position. Deglutition frequency and mean swallow duration were estimated from the long time series acquisition. Swallowing and resting (nonswallowing) events were identified on the short time series acquisidentified on the short time series acquisition and displacement was estimated based on contours of gross tumor volume (GTV) generated at each time point of a particular event. A simple linear relationship was derived to estimate 1D asymmetric IMs in the presence of resting- and deglutition-induced displacement. Results: Deglutition was nonperiodic, with frequency and duration ranging from 2.89-24.18 mHz and from 3.86 to 6.10 s, respectively. The deglutition frequency and mean duration were found to vary among patients. Deglutition-induced maximal GTV displacements ranged from 0.00 to 28.36 mm with mean and standard deviation of 4.72±3.18, 3.70±2.81, 2.75±5.24, and 10.40±10.76 mm in the A, P, I, and S directions, respectively. Resting-induced maximal GTV displacement ranged from 0.00 to 5.59 mm with mean and standard deviation of 3.01±1.80, 1.25±1.10, 3.23+2.20, and 2.47±1.11 mm in the A, P, I, and S directions, respectively. For both resting and swallowing states, displacement along the S-I direction dominated displacement along the A-P direction. The calculated IMs were dependent on deglutition frequency, ranging from 3.28-4.37 mm for the lowest deglutition frequency patient to 3.76-6.43 mm for the highest deglutition frequency patient. A statistically significant difference was detected between IMs calculated for P and S directions (p=0.0018). Conclusions: Cine MRI is able to capture tumor motion during deglutition. Swallowing events can be demarcated by MR signal intensity changes caused by anatomy containing fully relaxed spins that move medially into the imaging plane during deglutition. Deglutition is nonperiodic and results in dynamic changes in the tumor position. Deglutition-induced displacements are larger and more variable than resting displacements. The nonzero mean maximum resting displacement indicates that some tumor motion occurs even when the patient is not swallowing. Asymmetric IMs, derived from deglutition frequency, duration, and directional displacement, should be employed to account for tumor motion in HNC RT.

36

Internal margin assessment using cine MRI analysis of deglutition in head and neck cancer radiotherapy  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Intensity-modulated radiation therapy (IMRT) is a promising treatment modality for patients with head and neck cancer (HNC). The dose distributions from IMRT are static and, thus, are unable to account for variations and/or uncertainties in the relationship between the patient (region being treated) and the beam. Organ motion comprises one such source of this uncertainty, introduced by physiological variation in the position, size, and shape of organs during treatment. In the head and neck, the predominant source of this variation arises from deglutition (swallowing). The purpose of this study was to investigate whether cinematographic MRI (cine MRI) could be used to determine asymmetric (nonuniform) internal margin (IM) components of tumor planning target volumes based on the actual deglutition-induced tumor displacement. Methods: Five head and neck cancer patients were set up in treatment position on a 3 T MRI scanner. Two time series of single-slice, sagittal, cine images were acquired using a 2D FLASH sequence. The first time series was a 12.8 min scan designed to capture the frequency and duration of deglutition in the treatment position. The second time series was a short, 15 s scan designed to capture the displacement of deglutition in the treatment position. Deglutition frequency and mean swallow duration were estimated from the long time series acquisition. Swallowing and resting (nonswallowing) events were identified on the short time series acquisition and displacement was estimated based on contours of gross tumor volume (GTV) generated at each time point of a particular event. A simple linear relationship was derived to estimate 1D asymmetric IMs in the presence of resting- and deglutition-induced displacement. Results: Deglutition was nonperiodic, with frequency and duration ranging from 2.89-24.18 mHz and from 3.86 to 6.10 s, respectively. The deglutition frequency and mean duration were found to vary among patients. Deglutition-induced maximal GTV displacements ranged from 0.00 to 28.36 mm with mean and standard deviation of 4.72{+-}3.18, 3.70{+-}2.81, 2.75{+-}5.24, and 10.40{+-}10.76 mm in the A, P, I, and S directions, respectively. Resting-induced maximal GTV displacement ranged from 0.00 to 5.59 mm with mean and standard deviation of 3.01{+-}1.80, 1.25{+-}1.10, 3.23+2.20, and 2.47{+-}1.11 mm in the A, P, I, and S directions, respectively. For both resting and swallowing states, displacement along the S-I direction dominated displacement along the A-P direction. The calculated IMs were dependent on deglutition frequency, ranging from 3.28-4.37 mm for the lowest deglutition frequency patient to 3.76-6.43 mm for the highest deglutition frequency patient. A statistically significant difference was detected between IMs calculated for P and S directions (p=0.0018). Conclusions: Cine MRI is able to capture tumor motion during deglutition. Swallowing events can be demarcated by MR signal intensity changes caused by anatomy containing fully relaxed spins that move medially into the imaging plane during deglutition. Deglutition is nonperiodic and results in dynamic changes in the tumor position. Deglutition-induced displacements are larger and more variable than resting displacements. The nonzero mean maximum resting displacement indicates that some tumor motion occurs even when the patient is not swallowing. Asymmetric IMs, derived from deglutition frequency, duration, and directional displacement, should be employed to account for tumor motion in HNC RT.

Paulson, Eric S.; Bradley, Julie A.; Wang Dian; Ahunbay, Ergun E.; Schultz, Christoper; Li, X. Allen [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 (United States)

2011-04-15

37

Phase-contrast cine MRI revealing en valve mechanism in spontaneous third ventriculostomy: report of a case and literature review.  

Science.gov (United States)

A 50-year-old epileptic woman affected by hydrocephalus due to aqueductal stenosis was admitted to the hospital because of headache, dysarthria, and mild lateral pulsion. Cranial computed tomography (CT) revealed left cerebellar hemorrhage. Subsequent magnetic resonance imaging (MRI) of the brain demonstrated an enlarged ventricular system unchanged from prior studies. Flow-sensitive phase-contrast (PC) cine magnetic resonance imaging showed flow absence through the aqueduct and flow pulsations through the third ventricle floor in systole and diastole, consistent with spontaneous third ventricle patency. On stationary tissue images, the third ventricle floor and the mamillary body were displaced downward at systole and upward at diastole. Stenosis of the cerebral aqueduct of Sylvius was also shown. Retrospective evaluation of the sagittal T2-weighted images disclosed flow void at the level of the third ventricle floor. On-off movements of the third ventricle floor could account for chronic hydrocephalus persistence by an en valve mechanism. Spontaneous third ventriculostomy (STV) was diagnosed on the basis of these findings. STV is a rare condition occurring in chronic obstructive hydrocephalus patients as a result of longstanding pulsations against the walls of the third ventricle, the floor in particular. We reviewed the literature to establish which imaging and clinical findings could improve the identification of STV in patients affected by obstructive hydrocephalus. PMID:20619532

Bailey, Ariel; Pipitone, Nicolò; Zuccoli, Giulio

2010-11-01

38

Frequency analysis of CSF flow on cine-MRI in normal pressure hydrocephalus  

International Nuclear Information System (INIS)

To clarify the flow dynamics of intracranial cerebrospinal fluid (CSF) in normal pressure hydrocephalus (NPH), frequency analyses of CSF flow measured with an ECG-gated phase contrast cine magnetic resonance imaging (MRI) were performed. The amplitude and phase in the CSF flow spectra in the aqueduct were determined in patients with NPH after a subarachnoid hemorrhage (SAH-NPH group, n=26), an idiopathic NPH (I-NPH group, n=4), an asymptomatic ventricular dilation or a brain atrophy (VD group, n=21), and in healthy volunteers (control group, n=25). The changes of CSF flow spectra were also analyzed 5 and 15 minutes after an intravenous injection of acetazolamide. Moreover, a phase transfer function (PTF) calculated from the spectra of the driving vascular pulsation and CSF flow in the aqueduct were assessed in patients with SAH-NPH and control groups before and after acetazolamide injection. There values were compared with the pressure volume response (PVR). The amplitude of the 1st-3rd harmonics in the SAH-NPH or I-NPH group was significantly larger than in the control or VD group because of a decrease in compliance (increase in PVR). The phase of the 1st harmonic in the SAH-NPH group was significantly different from that in the control or VD group, but no difference was found between the control and VD groups. The amplitude of the 0-3rd harmonics increased, and the phase of the 1st harmonic changed in all groups after an acetazolamide injection. An evaluation of thetazolamide injection. An evaluation of the time course of the direct current of CSF flow provided further information about the compensatory faculty of the cerebrospinal cavity. A PTF of the 1st harmonic in the SAH-NPH group was significantly larger than in the control group, and a positive correlation was noted between PTF of the 1st harmonic and PVR. In conclusion, frequency analyses of CSF flow measured by cine-MRI make it possible to obtain noninvasively a more detailed picture of the pathophysiology of NPH and of changes in intracranial conditions. (author)

39

Evaluation the role of myocardial perfusion of MRI and MR cine in acute coronary syndrome  

International Nuclear Information System (INIS)

Objective: To evaluate the role of comprehensive cardiac MRI (CMRI) in diagnosis of patients with coronary artery disease (CAD). Methods; 55 patients with acute coronary syndrome underwent MR imaging 3-6 months after the reperfusion therapy. Short-axis images acquired by cine FIESTA sequence were used to analyze the motion of the different anatomy regions. Used the FGRE ET sequence to detect the patterns of the first-pass perfusion after injection of 0.2 mmol·kg-1 Gd-DTPA at a flow of 3 ml·s-1. 7-12 min later, MDE pulse sequence used to recognize the high signal in the myocardium. Results: At study entry, 38 subjects had the defect in the first-pass perfusion. The signal in the defect was significantly lower than that in the normal regions, which always in the sub-endocardium. 51 subjects had delayed enhancement regions in the myocardium at different degree and different range. The mean intensity of hyper-enhanced regions was 4.36 times higher compared with that of the regions without hyper-enhancement. the difference between the 2 regions had statistical significance. The extent of hyper-enhancement was significantly related to the abnormality of wall motion. The range of delayed enhancement was bigger than that of the first-perfusion defect. Conclusion: Comprehensive evidence of delayed hyper-enhancement, dysfunction of myocardium, and the defect of first-pass perfusion can be used to predict myocardial infarction infarction

40

Accuracy of left ventricular ejection fraction estimation by gated Tc-99m sestamibi SPECT: Comparison with breath hold Cine MRI  

International Nuclear Information System (INIS)

Full text: Left Ventricular Ejection Fraction (LVEF) is one of the most important functional parameters in clinical cardiology. Due to the high temporal and spatial resolution of Breath Hold Cine MRI (MRI), this technique is considered to be able to accurately estimate Left Ventricular volumes and hence LVEF. Recently, LVEF has been measured using Gated Tc-99m Sestamibi SPECT (GSSPECT) and a validation study comparing LVEF calculated by GSSPECT and MRI was performed. Over a four month period, 14 patients had both GSSPECT and MRI within a stable 7 day period. All patients were being investigated for CAD and the GSSPECT was performed as part of the routine myocardial perfusion imaging. GSSPECT was performed at rest one hour after peak exercise injection of Tc-99m Sestamibi (mean dose 1000 MBq, range 800- 1100 MBq) with imaging performed on Picker 1000 gamma camera or 3000 using standard 8 interval acquisition. All patients were analysed with the automated Picker QGS package. MRI was performed on a 1.5 T MRI( GE Signa Advantage) using a previously described breath hold Cine technique with data being acquired in the cardiac short axis. The entire LV was imaged with 10 cm contiguous short axis slices being acquired with 11-16 frames per slice, depending on heart rate. A semi automated volumetric image analysis program was used to estimate LV volumes using Simpson's rule. The range of LVEF was from 30% to 70%. Linear regression analysis demonstrated excellent agreement for ysis demonstrated excellent agreement for LVEF calculated by GSSPECT and MRI (y= -5.4 + 0.97 x, r=0.90). Automated estimation of LVEF using GSSPECT correlates well with LVEF estimations using MRI and can accurately estimate LVEF in routine clinical practice

41

CT and MRI normal findings  

International Nuclear Information System (INIS)

This book gives answers to questions frequently heard especially from trainees and doctors not specialising in the field of radiology: Is that a normal finding? How do I decide? What are the objective criteria? The information presented is three-fold. The normal findings of the usual CT and MRI examinations are shown with high-quality pictures serving as a reference, with inscribed important additional information on measures, angles and other criteria describing the normal conditions. These criteria are further explained and evaluated in accompanying texts which also teach the systematic approach for individual picture analysis, and include a check list of major aspects, as a didactic guide for learning. The book is primarily intended for students, radiographers, radiology trainees and doctors from other medical fields, but radiology specialists will also find useful details of help in special cases. (orig./CB)

42

Evaluation of early systolic flow pattern in left ventricle by tagging cine MRI in normal volunteers  

International Nuclear Information System (INIS)

The tagging method is a new technique, which permits to apply discretionary lines (tags) on MR images. To evaluate intra left ventricular (LV) flow pattern, we performed ECG-gated gradient field echo cine MRI using tagging method in five normal male volunteers, aged 22-42 years. The horizontal long axis view of LV was imaged by multiphasic field echo pulse sequence. The three parallel tags (basal, middle and apical portion) were established on the horizontal long axis view of LV just after the triggered QRS waves. And the initial two images (70 ms and 120 ms after the triggered QRS waves) were analyzed. On the two tags (middle and apical portion) of these three tags, we measured the distance of displacement of the tags on three points (the near site of IVS, middle portion and the near site of free wall) respectively. At 70 ms after the trigger point, the only tagged blood at the near site of free wall flowed toward the apex. At 120 ms after the trigger point, all the tagged blood flowed toward the outflow tract of LV. And the maximum blood flow velocity was observed at the near site of IVS on middle portion of LV (166.0 mm/s). These results coincided with earlier studies by Doppler echocardiography. But we could not observe intra LV blood flow patterns throughout one cardiac cycle in this pulse sequence, because the tags had flowed out from LV and had become unclear due to spin relaxation and mixing. We concluded that the tagging method was useful to evaluate intra leing method was useful to evaluate intra left ventricular blood flow patterns in early systolic phase. (author)

43

SU-C-17A-05: Quantification of Intra-Fraction Motion of Breast Tumors Using Cine-MRI  

International Nuclear Information System (INIS)

Purpose: Magnetic resonance imaging (MRI) enables direct characterization of intra-fraction motion ofbreast tumors, due to high softtissue contrast and geometric accuracy. The purpose is to analyzethis motion in early-stage breast-cancer patients using pre-operative supine cine-MRI. Methods: MRI was performed in 12 female early-stage breast-cancer patients on a 1.5-T Ingenia (Philips)wide-bore scanner in supine radiotherapy (RT) position, prior to breast-conserving surgery. Twotwodimensional (2D) T2-weighted balanced fast-field echo (cine-MRI) sequences were added tothe RT protocol, oriented through the tumor. They were alternately acquired in the transverse andsagittal planes, every 0.3 s during 1 min. A radiation oncologist delineated gross target volumes(GTVs) on 3D contrast-enhanced MRI. Clinical target volumes (CTV = GTV + 15 mm isotropic)were generated and transferred onto the fifth time-slice of the time-series, to which subsequents lices were registered using a non-rigid Bspline algorithm; delineations were transformed accordingly. To evaluate intra-fraction CTV motion, deformation fields between the transformed delineations were derived to acquire the distance ensuring 95% surface coverage during scanning(P95%), for all in-plane directions: anteriorposterior (AP), left-right (LR), and caudal-cranial(CC). Information on LR was derived from transverse scans, CC from sagittal scans, AP fromboth sets. Results: Time-series with registration errors - induced by motion artifacts - were excluded by visual inspection. For our analysis, 11 transverse, and 8 sagittal time-series were taken into account. Themedian P95% calculated in AP (19 series), CC (8), and LR (11) was 1.8 mm (range: 0.9–4.8), 1.7mm (0.8–3.6), and 1.0 mm (0.6–3.5), respectively. Conclusion: Intra-fraction motion analysis of breast tumors was achieved using cine-MRI. These first results show that in supine RT position, motion amplitudes are limited. This information can be used for adaptive RT planning, and to develop preoperative partial-breast RT strategies, such asablative RT for early-stage breast-cancer patients

44

MRI findings of bone tumor  

Energy Technology Data Exchange (ETDEWEB)

To investigate the usefulness of magnetic resonance imaging, MRI, of bone tumors, we retrospectively reviewed 32 MRI examination already diagnosed pathologically. Subjects included 18 males and 14 females, ranging in age from 5 to 63 years, with a means of 29.3 years. These included 25 benign bone tumors and 7 malignant bone tumors. The accuracy of a qualitative diagnosis was observed in giant cell tumor, osteoid osteoma, fibrous dysplasia and ossifying fibroma. In malignant bone tumors, it is difficult to accurately diagnose with MRI, although MRI was useful in showing interaction of the tumor and host tissue, extension, edema and reactive zone. (author)

Hamanaka, Hideaki; Kashiwagi, Teruyuki; Chosa, Etuo; Kuwahara, Shigeru; Tajima, Naoya [Miyazaki Medical Coll., Kiyotake (Japan)

1996-09-01

45

Respiratory lumenal change of the pharynx and trachea in normal subjects and COPD patients: assessment by cine-MRI  

International Nuclear Information System (INIS)

The purpose of this study was to use cine-MRI during continuous respiration to measure the respiratory lumenal diameter change in the pharynx and at an upper tracheal level. Fifteen non-smokers and 23 chronic obstructive pulmonary disease (COPD) patients with smoking history (median 50 pack-years) were included. Cine-MRI with seven frames/s was performed during continuous respiration. Minimal and maximal cross-sectional lumenal diameters within the pharynx and the upper tracheal lumen area were measured. The median diameter change in the pharynx (tracheal area) was 70% (1.4 cm2) in volunteers and 76% (1.7 cm2) in smokers (P=0.98, P=0.04). Tracheal lumenal collapse was a median of 43% in volunteers and 64% in smokers (P=0.011). No clear disease-related difference of the pharynx-lumen was found. The maximal cross-sectional area of the upper trachea lumen as well as the respiratory collapse was larger in COPD patients than in normal subjects. This information is important for the modelling of ventilation and prediction of drug deposition, which are influenced by the airway diameter. (orig.)

46

MRI findings of juvenile psoriatic arthritis  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study was to describe the magnetic resonance imaging (MRI) features of juvenile psoriatic arthritis (JpsA) in children in order to facilitate early diagnosis and proper management. Two pediatric radiologists retrospectively reviewed in consensus a total of 37 abnormal MRI examinations from 31 pediatric patients (nine boys, 22 girls; age range 1-17 years; mean age 9.4 years) who had a definite diagnosis of JpsA and underwent MRI. Each MRI was evaluated for synovium abnormality (thickening and enhancement), joint effusion (small, moderate, and large), bone marrow abnormality (edema, enhancement, and location of abnormality), soft tissue abnormality (edema, enhancement, atrophy, and fatty infiltration), tendon abnormality (thickening, edema, tendon sheath fluid, and enhancement), and articular abnormality (joint space narrowing and erosion). The distribution of abnormal MRI findings among the six categories for the 37 MRI examinations was evaluated. The number of abnormal MRI findings for each MRI examination was assessed. Age at MRI examination and all six categories of abnormal MRI findings according to gender were evaluated. There were a total 96 abnormal MRI findings noted on 37 abnormal MRI examinations from 31 pediatric patients. The 37 abnormal MRI examinations included MRI of the hand (n=8), knee (n = 8), ankle (n = 5), pelvis (n = 5), temporomandibular joint (n = 4), wrist (n = 3), foot (n = 2), elbow (n = 1), and shoulder (n = 1). Twenty-eight diffuse synovial thickening and/or enhancement were the most common MRI abnormality (29.2%). Joint effusion comprised 22 abnormal MRI findings (22.9%). There were 16 abnormal MRI bone marrow edema and/or enhancement findings (16.7%), and in seven (7.3%) the edema involved non-articular sites. Soft tissue abnormality manifested as edema and/or enhancement constituted 14 abnormal MRI findings (14.5%). There were ten MRI abnormalities (10.4%) involving tendons. Articular abnormality seen as joint space narrowing and/or bone erosion comprised six abnormal MRI findings (6.2%). Most MRI examinations had more than one abnormal finding (84%). Age at which MRI examinations were performed was not significantly different between boys and girls. All six categories of abnormal MRI findings were not significantly different between boys and girls. Children with JpsA typically present with more than one abnormal finding on their MRI studies. While synovial abnormality is the most common MR finding in children with JpsA, multi-focal bone marrow edema and enhancement at both articular and non-articular sites are also notable findings in children with JpsA. The rate of articular abnormality is much lower in children with JpsA in comparison to adults with psoriatic arthritis. Our findings suggest that MRI can play a useful role in the diagnosis and ongoing assessment of this uncommon, though important, pediatric rheumatologic disorder. (orig.)

Lee, Edward Y.; Kleinman, Paul K. [Harvard Medical School, Department of Radiology, Boston, MA (United States); Children' s Hospital Boston, MA (United States); Sundel, Robert P.; Kim, Susan [Harvard Medical School, Rheumatology Program, Division of Immunology and the Department of Pediatrics, Boston, MA (United States); Children' s Hospital Boston, MA (United States); Zurakowski, David [Harvard Medical School, Department of Radiology, Boston, MA (United States); Harvard Medical School, Department of Orthopaedic Surgery, Boston, MA (United States); Children' s Hospital Boston, MA (United States)

2008-11-15

47

MRI findings of juvenile psoriatic arthritis  

International Nuclear Information System (INIS)

The aim of this study was to describe the magnetic resonance imaging (MRI) features of juvenile psoriatic arthritis (JpsA) in children in order to facilitate early diagnosis and proper management. Two pediatric radiologists retrospectively reviewed in consensus a total of 37 abnormal MRI examinations from 31 pediatric patients (nine boys, 22 girls; age range 1-17 years; mean age 9.4 years) who had a definite diagnosis of JpsA and underwent MRI. Each MRI was evaluated for synovium abnormality (thickening and enhancement), joint effusion (small, moderate, and large), bone marrow abnormality (edema, enhancement, and location of abnormality), soft tissue abnormality (edema, enhancement, atrophy, and fatty infiltration), tendon abnormality (thickening, edema, tendon sheath fluid, and enhancement), and articular abnormality (joint space narrowing and erosion). The distribution of abnormal MRI findings among the six categories for the 37 MRI examinations was evaluated. The number of abnormal MRI findings for each MRI examination was assessed. Age at MRI examination and all six categories of abnormal MRI findings according to gender were evaluated. There were a total 96 abnormal MRI findings noted on 37 abnormal MRI examinations from 31 pediatric patients. The 37 abnormal MRI examinations included MRI of the hand (n=8), knee (n = 8), ankle (n = 5), pelvis (n = 5), temporomandibular joint (n = 4), wrist (n = 3), foot (n = 2), elbow (n = 1), and shoulder (n = 1). Twenty-eight d= 1), and shoulder (n = 1). Twenty-eight diffuse synovial thickening and/or enhancement were the most common MRI abnormality (29.2%). Joint effusion comprised 22 abnormal MRI findings (22.9%). There were 16 abnormal MRI bone marrow edema and/or enhancement findings (16.7%), and in seven (7.3%) the edema involved non-articular sites. Soft tissue abnormality manifested as edema and/or enhancement constituted 14 abnormal MRI findings (14.5%). There were ten MRI abnormalities (10.4%) involving tendons. Articular abnormality seen as joint space narrowing and/or bone erosion comprised six abnormal MRI findings (6.2%). Most MRI examinations had more than one abnormal finding (84%). Age at which MRI examinations were performed was not significantly different between boys and girls. All six categories of abnormal MRI findings were not significantly different between boys and girls. Children with JpsA typically present with more than one abnormal finding on their MRI studies. While synovial abnormality is the most common MR finding in children with JpsA, multi-focal bone marrow edema and enhancement at both articular and non-articular sites are also notable findings in children with JpsA. The rate of articular abnormality is much lower in children with JpsA in comparison to adults with psoriatic arthritis. Our findings suggest that MRI can play a useful role in the diagnosis and ongoing assessment of this uncommon, though important, pediatric rheumatologic disorder. (orig.)

48

Measurement of Strain in the Left Ventricle during Diastole with cine-MRI and Deformable Image Registration  

International Nuclear Information System (INIS)

The assessment of regional heart wall motion (local strain) can localize ischemic myocardial disease, evaluate myocardial viability and identify impaired cardiac function due to hypertrophic or dilated cardiomyopathies. The objectives of this research were to develop and validate a technique known as Hyperelastic Warping for the measurement of local strains in the left ventricle from clinical cine-MRI image datasets. The technique uses differences in image intensities between template (reference) and target (loaded) image datasets to generate a body force that deforms a finite element (FE) representation of the template so that it registers with the target image. To validate the technique, MRI image datasets representing two deformation states of a left ventricle were created such that the deformation map between the states represented in the images was known. A beginning diastoliccine-MRI image dataset from a normal human subject was defined as the template. A second image dataset (target) was created by mapping the template image using the deformation results obtained from a forward FE model of diastolic filling. Fiber stretch and strain predictions from Hyperelastic Warping showed good agreement with those of the forward solution. The technique had low sensitivity to changes in material parameters, with the exception of changes in bulk modulus of the material. The use of an isotropic hyperelastic constitutive model in the Warping analyses degraded the predictions oarping analyses degraded the predictions of fiber stretch. Results were unaffected by simulated noise down to an SNR of 4.0. This study demonstrates that Warping in conjunction with cine-MRI imaging can be used to determine local ventricular strains during diastole

49

Congenital dacryocystocele: prenatal MRI findings  

International Nuclear Information System (INIS)

Congenital dacryocystocele can be diagnosed prenatally by imaging. Prenatal MRI is increasingly utilized for fetal diagnosis. To present the radiological and clinical features of seven fetuses with congenital dacryocystocele diagnosed with prenatal MRI. The institutional database of 1,028 consecutive prenatal MR examinations performed during a period of 4 years was reviewed retrospectively. The cases of congenital dacryocystocele were identified by reading the report of each MRI study. The incidence of dacryocystocele diagnosed with prenatal MRI was 0.7% (n=7/1,028). The dacryocystocele was bilateral in three fetuses. Mean gestational age at the time of diagnosis was 31 weeks. The indication for prenatal MRI was the presence or the suspicion of central nervous system abnormality in six fetuses and diaphragmatic hernia in one. Dacryocystocele was associated with an intranasal cyst in six of ten eyes. Prenatal sonography revealed dacryocystocele in only two of seven fetuses. Of eight eyes with postnatal follow-up, four did not have any lacrimal symptoms. Prenatal MRI can delineate congenital dacryocystocele more clearly and in a more detailed fashion than ultrasonography. Presence of dacryocystocele was symptomatic in only 50% of our patients, supporting that prenatal diagnosis of dacryocystocele might follow a benign course. (orig.)

50

Assessment of ventricular coupling with real-time cine MRI and its value to differentiate constrictive pericarditis from restrictive cardiomyopathy  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to evaluate the use of respiratory-related ventricular coupling to differentiate patients with constrictive pericarditis (CP) and restrictive cardiomyopathy (RCM). In 18 histologically proven cases of CP, 6 patients with inflammatory pericarditis (IP), 15 RCM patients and 17 normal subjects, real-time cine MRI was performed in the cardiac short-axis (basal half of the ventricles) during operator-guided deep respiration. The images were analyzed for ventricular septal position and shape during early ventricular filling. Early diastolic septal inversion (I) or flattening (F) was found in all CP (I:15,F:3), and in all IP (I:2,F:4), but seldom in normals (F:1) and not in RCM. The septal abnormalities occurred at the onset of inspiration and rapidly disappeared with the next heartbeats. The amount of ventricular coupling was evaluated by quantifying the difference in the maximal septal excursion between inspiration and expiration. This parameter, normalized to the biventricular diameter, was significantly larger in CP (20.0{+-}4.5%, P<0.0001) and IP (14.8{+-}3.2%, P<0.0001) patients than in normals (7.0{+-}2.4%), whereas RCM patients had a trend toward decreased excursion (4.2{+-}1.7%, P=0.11). A cut-off value of 11.8% (mean normals +2 SD) enabled to differentiate CP patients from normals and RCM patients completely. Real-time cine MRI can easily depict increased ventricular coupling, which may be helpful to better differentiate between CP and RCM patients, especially in patients with normal or minimally thickened pericardium. The increase in coupling in IP patients is likely caused by decreased compliance of the inflamed pericardial layers. (orig.)

Francone, Marco; Dymarkowski, Steven; Kalantzi, Maria; Rademakers, Frank E.; Bogaert, Jan [Gasthuisberg University Hospital, Department of Radiology and Cardiology, Leuven (Germany)

2006-04-15

51

MRI findings of Rathke cleft cyst  

International Nuclear Information System (INIS)

The purpose of this study is to describe the characteristic MRI findings of the Rathke cleft cyst. During a seven-year period, we retrospectively evaluated the MRI findings of 24 pathologically-proven Rathke cleft cysts. The patients included ten men and 14 women, and their mean age was 37. MRI findings were analyzed in terms of location, shape, size, signal intensity, homogeneity of cyst content, pattern of contrast enhancement, displacement of the pituitary stalk, and mass effect of the cyst on adjacent structures. MRI findings of midline intrasellar cyst with a staging water bag appearance, high signal intensity on T1- and T2WI, inhomogeneity of cyst content, and peripheral rim enhancement surrounding the cyst are common, and are characteristic of the Rathke cleft cyst. (author). 23 refs., 5 figs

52

MRI findings of Guillain-Barre syndrome  

International Nuclear Information System (INIS)

To evaluate MRI findings of Guillain-Barre syndrome. In six patients with Guillain-Barre syndrome diagnosed by clinical, cerebrospinal fluid and electrophysiologic findings, a retrospective review of MR findings was conducted. Follow-up MRI scans were carried out in two patients showing minimal clinical improvement. Marked or moderate enhancement of thickened nerve roots was seen in all cases on gadopentetate dimeglumine enhanced axial T1-weighted images. Two patterns were seen; one was even enhancement of both anterior and posterior nerve roots (n=1) and the other was enhancement of anterior nerve roots only (n=5). Enhancement and thickness of nerve roots was seen to have slightly decreased on MRI follow-up at 32 and 50 days; clinical and electrophysiologic examination showed minimal improvement. Although MRI findings of nerve root enhancement are nonspecific and can be seen in neoplastic and other inflammatory diseases, the enhancement of thickened anterior nerve roots within the cal sac suggests Guillain-Barre syndrome

53

MRI findings in acute Hendra virus meningoencephalitis  

International Nuclear Information System (INIS)

Aim: To describe serial changes in brain magnetic resonance imaging (MRI) in acute human infection from two outbreaks of Hendra virus (HeV), relate these changes to disease prognosis, and compare HeV encephalitis to reported cases of Nipah virus encephalitis. Materials and methods: The MRI images of three human cases (two of which were fatal) of acute HeV meningoencephalitis were reviewed. Results: Cortical selectivity early in the disease is evident in all three patients, while deep white matter involvement appears to be a late and possibly premorbid finding. This apparent early grey matter selectivity may be related to viral biology or ribavirin pharmacokinetics. Neuronal loss is evident at MRI, and the rate of progression of MRI abnormalities can predict the outcome of the infection. In both fatal cases, the serial changes in the MRI picture mirrored the clinical course. Conclusion: This is the first comprehensive report of serial MRI findings in acute human cerebral HeV infection from two outbreaks. The cortical selectivity appears to be an early finding while deep white matter involvement a late, and possibly premorbid, finding. In both fatal cases, the serial changes in MRI mirrored the clinical course.

54

Vertebral involvement in SAPHO syndrome: MRI findings  

Energy Technology Data Exchange (ETDEWEB)

We report on the MRI findings in the vertebrae and surrounding soft tissues in two patients with the SAPHO syndrome (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis). The MRI findings include abnormal bone marrow signal, either focal or diffuse, of the vertebral bodies and posterior elements; hyperintense paravertebral soft tissue swelling and abnormal signal of the intervertebral discs. These changes are consistent with discitis and osteitis. (orig.) With 6 figs., 17 refs.

Nachtigal, A.; Cardinal, E.; Bureau, N.J. [Dept. of Radiology, Univ. de Montreal, QC (Canada); Sainte-Marie, L.G. [Dept. of Internal Medicine, Univ. de Montreal, QC (Canada); Milette, F. [Department of Pathology, Univ. de Montreal, QC (Canada)

1999-03-01

55

Vertebral involvement in SAPHO syndrome: MRI findings  

International Nuclear Information System (INIS)

We report on the MRI findings in the vertebrae and surrounding soft tissues in two patients with the SAPHO syndrome (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis). The MRI findings include abnormal bone marrow signal, either focal or diffuse, of the vertebral bodies and posterior elements; hyperintense paravertebral soft tissue swelling and abnormal signal of the intervertebral discs. These changes are consistent with discitis and osteitis. (orig.)

56

Delayed-enhancement MRI of apical hypertrophic cardiomyopathy: assessment of the intramural distribution and comparison with clinical symptoms, ventricular arrhythmias, and cine MRI  

Energy Technology Data Exchange (ETDEWEB)

Background: Hypertrophic cardiomyopathy (HCM) is reported to show patchy midwall myocardial hyper enhancement on delayed-enhancement magnetic resonance imaging (DE-MRI). The intramural distribution of myocardial hyper enhancement and its correlation with clinical symptoms, ventricular arrhythmias, and cardiac function have not been described for symptomatic apical HCM. Purpose: To evaluate the features and significance of myocardial hyper enhancement on DE-MRI in symptomatic apical HCM. Material and Methods: Thirteen patients with symptomatic apical HCM and their 65 apical segments were investigated. Myocardial hyper enhancement and regional and global functional parameters were determined with MRI. We investigated the intramural distribution and frequencies of this myocardial hyper enhancement and compared them with the patients' clinical symptoms, the presence of ventricular arrhythmias, and cine MRI. Results: Eight (61.5%) patients with symptomatic apical HCM displayed apical myocardial hyper enhancement, and 22 (33.8%) of the 65 apical segments examined showed myocardial hyper enhancement. Of the myocardial hyper enhancement observed, 81.8% showed a subendocardial pattern.The Hyperenhanced apical myocardium had a lower percentage of systolic myocardial thickening, and was associated with serious symptoms (e.g. syncope) and ventricular arrhythmias. Conclusion: Patients with symptomatic apical HCM showed myocardial hyper enhancement involving the subendocardial layer, which might be related to regional systolic dysfunction, serious clinical symptoms, and ventricular arrhythmias

Amano, Yasuo; Fukushima, Yoshimitsu; Kumita, Shinichiro (Dept. of Radiology, Nippon Medical School, Tokyo (Japan)), email: yas-amano@nifty.com; Takayama, Morimasa (Dept. of Cardiology, Sakakibara Heart Inst., Tokyo (Japan)); Kitamura, Mitsunobu (Coronary Care Unit, Chiba-Hokuso Hospital of Nippon Medical School, Chiba (Japan))

2011-07-15

57

Diffusion MRI findings in phenylketonuria  

International Nuclear Information System (INIS)

Two patients with phenylketonuria were studied who were under dietary control since infancy, and who were mentally normal. Diffusion MRI was obtained using a spin-echo, echo-planar sequence with a gradient strength of 30 mT/m at 1.5 T. A trace sequence (TR=5700 ms, and TE=139 ms) was used, acquired in 22 s. Heavily diffusion-weighted (b=1000 mm2/s) images, and the apparent diffusion coefficient (ADC) values from automatically generated ADC maps were studied. There were two different patterns in these two patients, restricted and increased diffusion patterns. Restricted diffusion pattern consisted of high-signal on b=1000 s/mm2 images with low ADC values ranging from 0.46 to 0.57 x 10-3 mm2/s. Increased diffusion pattern consisted of normal b=1000 s/mm2 images with high ADC values ranging from 1.37 to 1.63 x 10-3 mm2/s. It is likely that these values reflected presence of two different histopathological changes in phenylketonuria or reflected different stages of the same disease. (orig.)

58

Diffusion MRI findings in phenylketonuria  

Energy Technology Data Exchange (ETDEWEB)

Two patients with phenylketonuria were studied who were under dietary control since infancy, and who were mentally normal. Diffusion MRI was obtained using a spin-echo, echo-planar sequence with a gradient strength of 30 mT/m at 1.5 T. A trace sequence (TR=5700 ms, and TE=139 ms) was used, acquired in 22 s. Heavily diffusion-weighted (b=1000 mm{sup 2}/s) images, and the apparent diffusion coefficient (ADC) values from automatically generated ADC maps were studied. There were two different patterns in these two patients, restricted and increased diffusion patterns. Restricted diffusion pattern consisted of high-signal on b=1000 s/mm{sup 2} images with low ADC values ranging from 0.46 to 0.57 x 10{sup -3} mm{sup 2}/s. Increased diffusion pattern consisted of normal b=1000 s/mm{sup 2} images with high ADC values ranging from 1.37 to 1.63 x 10{sup -3} mm{sup 2}/s. It is likely that these values reflected presence of two different histopathological changes in phenylketonuria or reflected different stages of the same disease. (orig.)

Sener, R.N. [Dept. of Radiology, Ege Univ. Hospital, Izmir (Turkey)

2003-12-01

59

Peristalsis gap sign at cine magnetic resonance imaging for diagnosing strangulated small bowel obstruction. Feasibility study  

International Nuclear Information System (INIS)

The aim of this study was to determine the feasibility of cine magnetic resonance imaging (MRI) for diagnosing strangulated small bowel obstruction (SBO). This study included 38 patients with clinically confirmed SBO who had undergone cine MRI. Cine MRI scans were evaluated regarding the presence of the 'peristalsis gap sign' (referring to an akinetic or severely hypokinetic closed loop), indicating strangulation. Computed tomography (CT) was performed in 34 of 38 patients with (n=25) or without (n=9) contrast enhancement. CT images were evaluated using a combination of criteria (presence of hyperattenuation, poor contrast enhancement, mesenteric edema, wall thickening, massive ascites) indicating strangulation. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of cine MRI and CT for the diagnosis of strangulation were calculated and compared using surgical findings and the clinical course as the reference standard. Sensitivity, specificity, PPV, and NPV of cine MRI were 100%, 92.9%, 83.3%, and 100%, respectively; and those of CT (of which 26.5% was performed without contrast enhancement) were 66.7%, 92.0%, 75.0%, and 88.5%, respectively. There was no significant difference in diagnostic accuracy between the two methods (P=0.375). Cine MRI is a feasible and promising technique for diagnosing strangulation. (author)

60

MRI findings in the painful hemiplegic shoulder  

Energy Technology Data Exchange (ETDEWEB)

Aim: To evaluate the magnetic resonance imaging (MRI) findings in painful hemiplegic shoulder (PHS) in hemiplegic post-stroke patients. Materials and methods: Patients with hemiplegia following their first cerebrovascular accident who were admitted to the Sarah Network of Hospitals for Rehabilitation were studied. Forty-five patients with pain in the hemiplegic shoulder and 23 post-stroke patients without shoulder pain were investigated. MRI and radiographic findings of the hemiplegic and contralateral asymptomatic shoulders were evaluated. Results: Some MRI findings were more frequent in PHS group, including synovial capsule thickening, synovial capsule enhancement, and enhancement in the rotator cuff interval. Conclusions: Adhesive capsulitis was found to be a possible cause of PHS.

Tavora, D.G.F., E-mail: danielgurgel@sarah.b [Department of Radiology, Sarah Network of Hospitals for Rehabilitation, Fortaleza (Brazil); Gama, R.L.; Bomfim, R.C. [Department of Radiology, Sarah Network of Hospitals for Rehabilitation, Fortaleza (Brazil); Nakayama, M. [Department of Radiology, Federal University of Grande Dourados, Dourados (Brazil); Silva, C.E.P. [Department of Statistics, Sarah Network of Hospitals for Rehabilitation, Fortaleza (Brazil)

2010-10-15

61

Analysis of intracranial CSF flow dynamics in phase-contrast cine MRI  

International Nuclear Information System (INIS)

In order to clarify the flow dynamics of intracranial cerebrospinal fluid (CSF), experimental and clinical studies were performed with MR imaging. In an experiment, to-and-fro flow and bulk flow were simultaneously generated as CFS flow movement in an aqueduct. Under these conditions, the flow velocities and patterns were quantitatively measured with both phase-contrast cine MR imaging and an electromagnetic flow meter. The measured values from MR imaging mached those of the electromagnetic flow meter. Clinically, CSF flow measurement with MR imaging revealed that the maximum CSF flow velocity and the peak interval in the aqueduct were greater in patients with normal pressure hydrocephalus than in healthy volunteers. In conclusion, CSF flow analysis with MR imaging makes it possible to clarify noninvasively the pathophysiology of hydrocephalus and changes in the intracranial condition. (author)

62

Symptomatic Chiari malformation in infancy and adolescence; Cine-MRI and clinical evaluation  

Energy Technology Data Exchange (ETDEWEB)

Of the 7 children and adolescents with Chiari malformation reported here 5 had Chiari type 1 and 2 had Chiari type 2 disease. All 5 Chiari type 1 patients had syringomyelia and scoliosis, but the Chiari type 2 patients did not. All the patients except one with localized syringomyelia (case 3) underwent posterior decompression with suboccipital craniectomy, upper cervical laminectomy and duraplasty, and their clinical signs and symptoms improved. Case 3 received a syringo-subarachnoid shunt and improved clinically. Motor function was restored better than sensory function. Cranial nerve signs were cleared up in the Chiari type 2 patients. In the Chiari type 1 patients postoperative neurological improvement correlated well with the collapse of syringomyelia. Cine MR imaging was useful in the evaluation of CSF dynamics at the cranio-vertebral junction and in the syringomyelic cavity before and after surgery. (author).

Fukushima, Takeo; Matsuda, Toshihiro; Tsugu, Hitoshi; Sakamoto, Seisaburou; Tomonaga, Masamichi; Asakawa, Koji; Mitsudome, Akihisa (Fukuoka Univ. (Japan). School of Medicine); Hashimoto, Takahisa

1994-04-01

63

Study on MRI findings in postresuscitation brains  

International Nuclear Information System (INIS)

We evaluated chronological changes in T1/T2-weighted and diffusion-weighted magnetic resonance imaging (MRI) findings in patients with global cerebral ischemia compared to computed tomography (CT) and single photon emission computed tomography (SPECT) to determine the advantages this presents in determining a patient's prognosis. We retrospectively studied MRI in 28 patients resuscitated after cardiopulmonary arrest. Patients were divided by outcome into 4 groups -- good outcome in 5, moderate disability in 2, vegetative in 17, and 4 brain-dead. Those with good recovery had normal CT and MRI findings. Those with moderate disability demonstrated high signal intensity in basal ganglia and posterior cerebral cortex during the chronic period. All vegetative patients had abnormal CT findings and their T2-weighted images during the acute period demonstrated high signal intensity in the cerebral cortex and basal ganglia; T1-weighted image during the chronic period showed similar findings, while diffusion-weighted images indicated high signal intensity in the cerebral cortex from the very acute period, during which abnormal findings were seen in the cortex, putamen, and thalamus more frequently than in T2-weighted images. Moreover, regional cerebral blood flow significantly decreased during the chronic period. All brain-dead patients had CT findings of diffuse cerebral edema and loss of density difference between gray and white matter. T2-weighted images respectively showed a. T2-weighted images respectively showed an extraordinary high density difference between gray and white matter and diffusion-weighted images high signal density in the whole brain. MRI detects chronologic changes in postresuscitation brain damage better than CT findings. Diffusion-weighted images identify hypoxic-ischemic lesions during the very acute period. MRI thus appears useful in evaluating patient prognosis and care. (author)

64

MRI findings in intramuscular lipomas  

Energy Technology Data Exchange (ETDEWEB)

Objective. To investigate the spectrum of magnetic resonance (MR) findings of intramuscular lipoma. Design and patients. A retrospective review of 17 consecutive cases of intramuscular lipoma examined with MR imaging was undertaken. Features assessed included the size and margin of the mass; the homogeneity of the contents, including the presence or absence of intermingled muscle fibers; whether the mass was uninodular or multinodular; and the presence of linear structures between and within the tumor nodules. Three well-differentiated liposarcomas and one dedifferentiated liposarcoma associated with lipoma-like components were also studied to allow a comparison of the benign and malignant lesions. Results. The diameter of the intramuscular lipomas varied from less than 3 cm to more than 10 cm. Ten of the intramuscular lipomas were homogeneous but the remaining seven were inhomogeneous with intermingled muscle fibers within the mass. The intramuscular lipomas were well defined in 12 cases, and infiltrative in five. In one case the margin of the lesion showed prominent infiltration of the surrounding muscle tissue. Of the 17 cases of intramuscular lipoma, 15 were composed of a single nodule, whereas three of four cases of liposarcoma were composed of multinodular masses. Conclusion. The MR findings of intramuscular lipoma varied from a small, single and homogeneous mass identical to ordinary (superficial) lipoma, to a large, inhomogeneous lesion with an infiltrative margin. The presence of infiltrative margins and intermingled muscle fibers in intramuscular lipoma indicates a benign lesion rather than malignancy. In addition, uninodularity of the mass is helpful in differentiating intramuscular lipoma from well-differentiated liposarcoma. (orig.) With 8 figs., 2 tabs., 17 refs.

Matsumoto, K.; Hukuda, Sinsuke; Ishizawa, Michihito; Chano, Tokuhiro [Dept. of Orthopaedic Surgery, Shiga University of Medical Science, Otsu (Japan); Okabe, Hidetoshi [Division of Surgical Pathology, Shiga University of Medical Science, Otsu (Japan)

1999-03-01

65

MRI findings in intramuscular lipomas  

International Nuclear Information System (INIS)

Objective. To investigate the spectrum of magnetic resonance (MR) findings of intramuscular lipoma. Design and patients. A retrospective review of 17 consecutive cases of intramuscular lipoma examined with MR imaging was undertaken. Features assessed included the size and margin of the mass; the homogeneity of the contents, including the presence or absence of intermingled muscle fibers; whether the mass was uninodular or multinodular; and the presence of linear structures between and within the tumor nodules. Three well-differentiated liposarcomas and one dedifferentiated liposarcoma associated with lipoma-like components were also studied to allow a comparison of the benign and malignant lesions. Results. The diameter of the intramuscular lipomas varied from less than 3 cm to more than 10 cm. Ten of the intramuscular lipomas were homogeneous but the remaining seven were inhomogeneous with intermingled muscle fibers within the mass. The intramuscular lipomas were well defined in 12 cases, and infiltrative in five. In one case the margin of the lesion showed prominent infiltration of the surrounding muscle tissue. Of the 17 cases of intramuscular lipoma, 15 were composed of a single nodule, whereas three of four cases of liposarcoma were composed of multinodular masses. Conclusion. The MR findings of intramuscular lipoma varied from a small, single and homogeneous mass identical to ordinary (superficial) lipoma, to a large, inhomogeneous lesion with an infiltrative mahomogeneous lesion with an infiltrative margin. The presence of infiltrative margins and intermingled muscle fibers in intramuscular lipoma indicates a benign lesion rather than malignancy. In addition, uninodularity of the mass is helpful in differentiating intramuscular lipoma from well-differentiated liposarcoma. (orig.)

66

MRI and CT findings of intracranial neurosyphilis  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the CT and MRI findings of neurosyphilis. We retrospectively reviewed the CT and MR imaging findings in five patients with intracranial neurosyphilis confirmed by CSF, VDRL, TPHA, and clinical follow-up. MR imaging was performed in all five cases, and CT in two. The MRI and CT findings of intracranial neurosyphilis included infarction (n=3), focal inflammation (n=1) and encephalopathy (n=1). There was a total of ten infaretions : three of the basal ganglia, two each of the frontal lobe, watershed zone, and cerebellum, and one of the occipital lobe. Intaretion was most common in MCA territory (n=9; 50%), followed by the watershed zone (16.6%), posterior cerebral artery territory (16.6%), and posterior inferior cerebellar artery territory (11.1%). The size of the lesion varied from 1cm to larger than one lobe. One patient showed diffuse high signal intensity in the left temporal lobe, but on follow-up MRI, this had resolved. The most common finding of neurosyphilis, as seen on MRI and CT, was infarction in middle cerebral arterial territory.

Suh, Hong Kil; Shim, Ya Seong; Kim, Seon Bok; Kim, Uk Jung; Lee, Shin Ho; Jung, Hae Kyuong; Lee, Eil Seong; Kang, Ik Won [Hallym University College of Medicine, Seoul (Korea, Republic of); Cho, Hyeun Cha [Sungkyunkwan University College of Medicine, Seoul (Korea, Republic of)

1999-02-01

67

MRI and CT findings of intracranial neurosyphilis  

International Nuclear Information System (INIS)

To evaluate the CT and MRI findings of neurosyphilis. We retrospectively reviewed the CT and MR imaging findings in five patients with intracranial neurosyphilis confirmed by CSF, VDRL, TPHA, and clinical follow-up. MR imaging was performed in all five cases, and CT in two. The MRI and CT findings of intracranial neurosyphilis included infarction (n=3), focal inflammation (n=1) and encephalopathy (n=1). There was a total of ten infaretions : three of the basal ganglia, two each of the frontal lobe, watershed zone, and cerebellum, and one of the occipital lobe. Intaretion was most common in MCA territory (n=9; 50%), followed by the watershed zone (16.6%), posterior cerebral artery territory (16.6%), and posterior inferior cerebellar artery territory (11.1%). The size of the lesion varied from 1cm to larger than one lobe. One patient showed diffuse high signal intensity in the left temporal lobe, but on follow-up MRI, this had resolved. The most common finding of neurosyphilis, as seen on MRI and CT, was infarction in middle cerebral arterial territory

68

MRI findings of treated bacterial septic arthritis  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to report the MRI findings that can be encountered in successfully treated bacterial septic arthritis. The study included 12 patients (8 male and 4 female; mean age 38 years, range 9-85) with 13 proven cases of bacterial septic arthritis. The joints involved were hip (n = 3), knee (n = 3), shoulder (n = 2), sacroiliac (n = 2), ankle (n = 1), wrist (n = 1), and elbow (n = 1). MRI examinations following surgical debridement and at initiation of antibiotic therapy and after successful treatment were compared for changes in effusion, synovium, bone, and periarticular soft tissues. Imaging findings were correlated with microbiological and clinical findings. Joint effusions were present in all joints at baseline and regressed significantly at follow-up MRI (p = 0.001). Abscesses were present in 5 cases (38 %), and their sizes decreased significantly at follow-up (p = 0.001). Synovial enhancement and thickening were observed in all joints at both baseline and follow-up MRI. Myositis/cellulitis was present in 10 cases (77 %) at baseline and in 8 cases (62 %) at follow-up MRI. Bone marrow edema was present in 10 joints (77 %) at baseline and persisted in 8 joints (62 %). Bone erosions were found in 8 joints (62 %) and persisted at follow-up MRI in all cases. The sizes of joint effusions and abscesses appear to be the factors with the most potential for monitoring therapy for septic arthritis, since both decreased significantly following successful treatment. Synovial thickening and enhancement, periarticular myositis/cellulitis, and bone marrow edema can persist even after resolution of the infection. (orig.)

Bierry, Guillaume; Huang, Ambrose J.; Chang, Connie Y.; Torriani, Martin; Bredella, Miriam A. [Massachusetts General Hospital and Harvard Medical School, Musculoskeletal Imaging and Intervention, Department of Radiology, Boston, MA (United States)

2012-12-15

69

A technique to reduce motion artifact for externally triggered cine-MRI(EC-MRI) based on detecting the onset of the articulated word with spectral analysis  

International Nuclear Information System (INIS)

One issue in externally triggered cine-magnetic resonance imaging (EC-MRI) for the dynamic observation of speech organs is motion artifact in the phase-encoding direction caused by unstable repetitions of speech during data acquisition. We propose a technique to reduce such artifact by rearranging the k-space data used to reconstruct MR images based on the analysis of recorded speech sounds. We recorded the subject's speech sounds during EC-MRI and used post hoc acoustical processing to reduce scanning noise and detect the onset of each utterance based on analysis of the recorded sounds. We selected each line of k-space from several data acquisition sessions and rearranged them to reconstruct a new series of dynamic MR images according to the analyzed time of utterance onset. Comparative evaluation showed significant reduction in motion artifact signal in the dynamic MR images reconstructed by the proposed method. The quality of the reconstructed images was sufficient to observe the dynamic aspects of speech production mechanisms. (author)

70

Percent wall thickness evaluated by Gd-DTPA enhanced cine MRI as an indicator of local parietal movement in hypertrophic cardiomyopathy  

International Nuclear Information System (INIS)

Hypertrophic cardiomyopathy (HCM) is a cardiac disease, the basic pathology of which consists of a decrease in left ventricular dilation compliance due to uneven hypertrophy of the left ventricular wall. Magnetic resonance imaging (MRI) is useful in monitoring uneven parietal hypertrophy and kinetics in HCM patients. The present study was undertaken in 47 HCM patients who showed asymmetrical septal hypertrophy to determine if percent thickness can be an indicator of left ventricular local movement using cine MRI. Longest and shortest axis images were acquired by the ECG synchronization method using a 1.5 T MR imager. Cardiac function was analyzed based on longest axis cine images, and telediastolic and telesystolic parietal thickness were measured based on shorter axis cine images at the papillary muscle level. Parietal movement index and percent thickness were used as indicators of local parietal movement. The correlation between these indicators and parietal thickness was evaluated. The percent thickness changed at an earlier stage of hypertrophy than the parietal movement index, thus it is thought to be useful in detecting left ventricular parietal movement disorders at an early stage of HCM. (author)

71

Percent wall thickness evaluated by Gd-DTPA enhanced cine MRI as an indicator of local parietal movement in hypertrophic cardiomyopathy  

Energy Technology Data Exchange (ETDEWEB)

Hypertrophic cardiomyopathy (HCM) is a cardiac disease, the basic pathology of which consists of a decrease in left ventricular dilation compliance due to uneven hypertrophy of the left ventricular wall. Magnetic resonance imaging (MRI) is useful in monitoring uneven parietal hypertrophy and kinetics in HCM patients. The present study was undertaken in 47 HCM patients who showed asymmetrical septal hypertrophy to determine if percent thickness can be an indicator of left ventricular local movement using cine MRI. Longest and shortest axis images were acquired by the ECG synchronization method using a 1.5 T MR imager. Cardiac function was analyzed based on longest axis cine images, and telediastolic and telesystolic parietal thickness were measured based on shorter axis cine images at the papillary muscle level. Parietal movement index and percent thickness were used as indicators of local parietal movement. The correlation between these indicators and parietal thickness was evaluated. The percent thickness changed at an earlier stage of hypertrophy than the parietal movement index, thus it is thought to be useful in detecting left ventricular parietal movement disorders at an early stage of HCM. (author)

Hirano, Masaharu [Tokyo Medical Coll. (Japan)

1998-11-01

72

Increased pulsatile movement of the hindbrain in syringomyelia associated with the Chiari malformation: cine-MRI with presaturation bolus tracking  

Energy Technology Data Exchange (ETDEWEB)

Cine-MRI with presaturation bolus tracking was used in patients with syringomyelia associated with a Chiari malformation to study pulsatile movement of the hindbrain, cervical spinal cord, cerebrospinal fluid and the fluid within the syrinx. Nine patients had 13 examinations, 6 preoperative, 3 after syringosubarachnoid shunting and 4 after posterior fossa decompression. Five controls were also examined. Dynamic display of the acquired images demonstrated downward displacement of the presaturation bolus on the cerebellar tonsils and medulla oblongata (or upper cervical cord) at the C1 level in all preoperative examinations and in two patients after syringo-subarachnoid shunting but with residual foramen magnum obstruction. Downward displacement of the bolus on the cervical spinal cord was also demonstrated in 7 examinations, but not observed in the controls. Thus, the hindbrain-spinal cord axis showed larger pulsatile movements in patients with foramen magnum obstruction. Based on these observations and a review of the literature, a new theory on the mode of extension of syringomyelia, emphasising the role of increased pulsatile movement of the hindbrain-spinal cord axis is proposed: that the pulsatile movements, together with a one-way valve mechanism in the syrinx cavity act as a ``vacuum-pump`` to enlarge the syrinx. (orig.)

Terae, S. [Hokkaido Univ. School of Medicine, Sapporo (Japan). Dept. of Radiology; Miyasaka, K. [Hokkaido Univ. School of Medicine, Sapporo (Japan). Dept. of Radiology; Abe, S. [Hokkaido Univ. School of Medicine, Sapporo (Japan). Dept. of Radiology; Abe, H.; Tashiro, K. [Hokkaido Univ. School of Medicine, Sapporo (Japan). Dept. of Neurology

1994-02-01

73

Increased pulsatile movement of the hindbrain in syringomyelia associated with the Chiari malformation: cine-MRI with presaturation bolus tracking  

International Nuclear Information System (INIS)

Cine-MRI with presaturation bolus tracking was used in patients with syringomyelia associated with a Chiari malformation to study pulsatile movement of the hindbrain, cervical spinal cord, cerebrospinal fluid and the fluid within the syrinx. Nine patients had 13 examinations, 6 preoperative, 3 after syringosubarachnoid shunting and 4 after posterior fossa decompression. Five controls were also examined. Dynamic display of the acquired images demonstrated downward displacement of the presaturation bolus on the cerebellar tonsils and medulla oblongata (or upper cervical cord) at the C1 level in all preoperative examinations and in two patients after syringo-subarachnoid shunting but with residual foramen magnum obstruction. Downward displacement of the bolus on the cervical spinal cord was also demonstrated in 7 examinations, but not observed in the controls. Thus, the hindbrain-spinal cord axis showed larger pulsatile movements in patients with foramen magnum obstruction. Based on these observations and a review of the literature, a new theory on the mode of extension of syringomyelia, emphasising the role of increased pulsatile movement of the hindbrain-spinal cord axis is proposed: that the pulsatile movements, together with a one-way valve mechanism in the syrinx cavity act as a ''vacuum-pump'' to enlarge the syrinx. (orig.)

74

Characterization of Pancreatic Tumor Motion Using Cine MRI: Surrogates for Tumor Position Should Be Used With Caution  

International Nuclear Information System (INIS)

Purpose: Our current understanding of intrafraction pancreatic tumor motion due to respiration is limited. In this study, we characterized pancreatic tumor motion and evaluated the application of several radiotherapy motion management strategies. Methods and Materials: Seventeen patients with unresectable pancreatic cancer were enrolled in a prospective internal review board-approved study and imaged during shallow free-breathing using cine MRI on a 3T scanner. Tumor borders were agreed on by a radiation oncologist and an abdominal MRI radiologist. Tumor motion and correlation with the potential surrogates of the diaphragm and abdominal wall were assessed. These data were also used to evaluate planning target volume margin construction, respiratory gating, and four-dimensional treatment planning for pancreatic tumors. Results: Tumor borders moved much more than expected. To provide 99% geometric coverage, margins of 20 mm inferiorly, 10 mm anteriorly, 7 mm superiorly, and 4 mm posteriorly are required. Tumor position correlated poorly with diaphragm and abdominal wall position, with patient-level Pearson correlation coefficients of -0.18-0.43. Sensitivity and specificity of gating with these surrogates was also poor, at 53%-68%, with overall error of 35%-38%, suggesting that the tumor may be underdosed and normal tissues overdosed. Conclusions: Motion of pancreatic tumor borders is highly variable between patients and larger than expected. There is substantial deformahan expected. There is substantial deformation with breathing, and tumor border position does not correlate well with abdominal wall or diaphragmatic position. Current motion management strategies may not account fully for tumor motion and should be used with caution.

75

MRI findings on de Quervain's disease  

International Nuclear Information System (INIS)

De Quervain's disease is a stenosing tenosynovitis affecting the first extensor compartment of the wrist. Conservative treatment including steroid injection is primarily indicated and satisfactory result can be obtained in most cases. However, it often fails in cases where fibrocartilagenous septum exists within the first compartment. Surgical release of the compartment and resection of the septum is recommended for these instances. The incidence of the septum in the compartment is reported to be about 30 to 40 per cent in normal population, though over 90 per cent in operative cases. In this study, MRI was employed to evaluate the anatomical variation in the first extensor compartment of the wrist in de Quervain's disease. There were 13 hands in 5 men and 10 women. Their average age was 49.5 years old (19 to 76 y.o.). Axial T1 weighted MR images around the radial styloid process were obtained. Eight hands which resisted conservative treatment were operated on and first compartment was directly inspected. The other 5 were well treated with one or two steroid injection. In all operative cases, MRI revealed that the EPB tendon exists apart from the APL tendon surrounded with thick high intensity area. That finding correspond to the operative findings. That were fibrocartilagenous septum dividing the first compartment and dense synovium around the EPB tendon. On the other hands, in 5 hands which responded to steroid injection, EPB was identified only in 2 on MRI and coulB was identified only in 2 on MRI and could not be distinguished from APL in the other 3. Consequently, MRI provides useful information to make a strategy for treating de Quervain's disease. In cases whose MRI show that EPB and APL are accommodated in one common canal non-surgical treatment should be continued while in the cases of separate EPB tunnel with surrounding proliferating synovium early operation might be considered. (author)

76

Extended MRI findings of intersection syndrome  

Energy Technology Data Exchange (ETDEWEB)

The symptoms and physical findings of intersection syndrome have been well described in the clinical medical literature. However, the magnetic resonance imaging (MRI) findings in patients with intersection syndrome of the forearm have only recently been described in a small number of patients. We review our experience with imaging of intersection syndrome, describe previously unreported MRI findings, and emphasize modifications to MRI protocols for its evaluation. Institutional review board approval was obtained for this retrospective review of patients with MRI findings consistent with intersection syndrome of the forearm during the period from January 2004 to September 2006. Six patients were identified, three males and three females, with an average age of 39.3 years. The MRI examinations were reviewed to assess signal abnormalities within and adjacent to the first and second dorsal extensor tendon compartments (DETC): tendinosis, peritendinous edema or fluid, muscle edema, subcutaneous edema, and juxtacortical edema. The overall longitudinal extent of signal alterations was measured as well as the distance from Lister's tubercle to the crossover of the first and second DETC. Review of the MRIs showed increased intrasubstance tendon signal suggesting tendinosis in two of the six patients, peritendinous edema or fluid in all six patients, muscle edema in five of the six patients, and subcutaneous edema in three of the six patients. Juxtacortical edema was seen in one patient. Peritendinous edema or fluid extended distally beyond the radiocarpal joint in three of the six patients. The average distance from Lister's tubercle to the crossover of the first and second DETC was 3.95 cm, in keeping with recently published data. Intersection syndrome is an uncommon MRI diagnosis. In addition to the previously described MRI findings of edema adjacent to the first or second DETC, possibly with proximal extension and subcutaneous edema, we have identified additional abnormalities: tendinosis, muscle edema, and juxtacortical edema. In addition, our review shows that first and second DETC signal abnormalities in patients with intersection syndrome are not necessarily limited to the site of crossover but can extend distally beyond the radiocarpal joint. As standard wrist protocols may not include the area of intersection between the first and second DETC, coverage may need to be extended to the mid-forearm. (orig.)

Lee, Roger P.; Hatem, Stephen F.; Recht, Michael P. [Cleveland Clinic, Cleveland, OH (United States)

2009-02-15

77

MRI findings and diagnosis of brain echinococcus  

International Nuclear Information System (INIS)

Objective: To study the characteristic findings of brain echinococcosis on MRI. Methods: The MRI findings of 18 patients with pathologically confirmed brain echinococcosis were retrospectively reviewed. Results: Among the patients, there were 9 cases of cystic echinococcosis and 9 cases of alveolar echinococcosis. In cystic echinococcosis, MRI revealed homogeneously hypointensity on T1WI and hyperintensity on T2WI, while it showed low signal intensity inside the cysts on FLAIR and DWI. In 6 cases of cystic echinococcosis, no edema was detected surrounding the lesions, while edema resulting from cyst rupture was found in 3 cases. The cystic walls were visible in 6 cases, obscure in 3 cases. The ruptured hydatid cysts in 3 cases showed slight ring enhancement. Alveolar echinococcosis appeared as multiple lesions with isointensity on T1WI and hypointensity on T2WI, surrounded by vasogenic edema. The 'charcoal-like' hypointensity and innumerous hyperintense bubbles of 1-10 mm in diameter inside the lesions on T2-weighted MR images were characteristic for lesions of alveolar echinococcosis. The lesions revealed hypointensity on DWI and showed irregular ring enhancement after injection of Gd-DTPA. Perfusion-weighted MR imaging revealed low relative cerebral blood volume. Conclusion: MRI can demonstrate lesions of brain echinococcosis accurately due to its advantages of multiorientation and multiparameter. It is clinically valuable. (authors)

78

Gastrointestinal stromal tumors: CT and MRI findings  

International Nuclear Information System (INIS)

The objective of this study was to report the CT and MRI appearances of primary and metastatic gastrointestinal stromal tumor (GIST). The clinical and imaging findings of 31 patients with histological and immunohistochemical diagnosis of GIST were reviewed. The CT and MRI findings were assessed independently for size, location, enhancement characteristics, and pattern of metastatic disease. The tumors were of enteric (n=13), gastric (n=12), duodenal (n=2), and rectal (n=3) origin. In one case the primary site was the mesentery, without involvement of bowel. Primary tumors were typically exophytic (79%), larger than 5 cm (84%), and inhomogeneously enhancing (84%). Central necrosis of all tumors (37%) and aneurysmal dilation of enteric tumors (33%) were less common. Metastases were most commonly to mesentery (26%) or liver (32%). Less common findings were ascites (7%) and omental caking (3%). Liver metastases were hypervascular in 92% of patients and rapidly became cystic following therapy with imatinib mesylate (Gleevec; Novartis, East Hanover, NJ, USA). Lung metastases, bowel obstruction, vascular invasion, and significant lymphadenopathy were not seen in any patient. GISTs have some specific CT findings which could help differentiate them from other gastrointestinal tumors. Liver metastases became cystic following therapy, mimicking simple cysts. MRI was better than single-phase CT for assessing liver metastases, while CT was more sensitive for mesenteric metastases. more sensitive for mesenteric metastases. (orig.)

79

Gastrointestinal stromal tumors: CT and MRI findings  

Energy Technology Data Exchange (ETDEWEB)

The objective of this study was to report the CT and MRI appearances of primary and metastatic gastrointestinal stromal tumor (GIST). The clinical and imaging findings of 31 patients with histological and immunohistochemical diagnosis of GIST were reviewed. The CT and MRI findings were assessed independently for size, location, enhancement characteristics, and pattern of metastatic disease. The tumors were of enteric (n=13), gastric (n=12), duodenal (n=2), and rectal (n=3) origin. In one case the primary site was the mesentery, without involvement of bowel. Primary tumors were typically exophytic (79%), larger than 5 cm (84%), and inhomogeneously enhancing (84%). Central necrosis of all tumors (37%) and aneurysmal dilation of enteric tumors (33%) were less common. Metastases were most commonly to mesentery (26%) or liver (32%). Less common findings were ascites (7%) and omental caking (3%). Liver metastases were hypervascular in 92% of patients and rapidly became cystic following therapy with imatinib mesylate (Gleevec; Novartis, East Hanover, NJ, USA). Lung metastases, bowel obstruction, vascular invasion, and significant lymphadenopathy were not seen in any patient. GISTs have some specific CT findings which could help differentiate them from other gastrointestinal tumors. Liver metastases became cystic following therapy, mimicking simple cysts. MRI was better than single-phase CT for assessing liver metastases, while CT was more sensitive for mesenteric metastases. (orig.)

Sandrasegaran, Kumaresan; Rydberg, Jonas; Akisik, Fatih M. [Indiana University Medical Center, Department of Radiology, Indianapolis, IN (United States); Rajesh, Arumugam [United Leicester Hospitals, Department of Radiology, Leicester (United Kingdom); Rushing, Daniel A. [Indiana University Medical Center, Department of Oncology, Indianapolis, Indiana (United States); Henley, John D. [Indiana University Medical Center, Department of Pathology, Indianapolis, Indiana (United States)

2005-07-01

80

Brain MRI findings of neuropsychiatric lupus  

International Nuclear Information System (INIS)

To evaluate the brain MRI findings in patients with neuropsychiatric lupus. In 26 patients (M:F = 2:24 ; aged 9-48 years) in whom the presence of systemic lupus erythematosus was clinically or pathologically proven and in whom neuropsychiatric lupus was also clinically diagnosed, the findings of brain MRI were retrospectively evaluated. MR images were analyzed with regard to the distribution, location, size and number of lesions due to cerebral ischemia or infarction, the presence of cerebral atrophy, and the extent and degree of brain parenchymal and intravascular enhancement. The most common MRI findings were lesions due to cerebral ischemia or infarction occurring in 18 patients (69%), and located within deep periventricular white matter (n=10), subcortical white matter (n=8), the cerebral cortex (n=7), basal ganglia (n=7), or brain stem or cerebellum (n=2). The lesions were single (n=3) or multiple (n=15), and in 17 patients were less than 1cm in diameter in regions other than the cerebral cortex. In six of these patients, lesions of 1-4cm in diameter in this region were combined, and one occurred in the cerebral cortex only. Cerebral atrophy was seen in 16 patients (62%), in ten of whom there was no past history of treatment with steroids for more than six months. In 15 patients (58%), contrast-enhanced MR image revealed diffuse enhancement of the basal ganglia or intravascular enhancement. In no case were MRI findings normal. The primary mainfestations of neuroprmal. The primary mainfestations of neuropsychiatric lupus are multifocal ischemia or infarctions in the cerebral cortex, and subcortical and deep white matter, and the cerebral atrophy. Contrast-enhanced MR images also demonstrated diffuse enhancement of the basal ganglia and intravascular enhancement, both thought to be related to the congestion due to the stagnation of cerebral blood flow

81

Brain MRI findings of neuropsychiatric lupus  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the brain MRI findings in patients with neuropsychiatric lupus. In 26 patients (M:F = 2:24 ; aged 9-48 years) in whom the presence of systemic lupus erythematosus was clinically or pathologically proven and in whom neuropsychiatric lupus was also clinically diagnosed, the findings of brain MRI were retrospectively evaluated. MR images were analyzed with regard to the distribution, location, size and number of lesions due to cerebral ischemia or infarction, the presence of cerebral atrophy, and the extent and degree of brain parenchymal and intravascular enhancement. The most common MRI findings were lesions due to cerebral ischemia or infarction occurring in 18 patients (69%), and located within deep periventricular white matter (n=10), subcortical white matter (n=8), the cerebral cortex (n=7), basal ganglia (n=7), or brain stem or cerebellum (n=2). The lesions were single (n=3) or multiple (n=15), and in 17 patients were less than 1cm in diameter in regions other than the cerebral cortex. In six of these patients, lesions of 1-4cm in diameter in this region were combined, and one occurred in the cerebral cortex only. Cerebral atrophy was seen in 16 patients (62%), in ten of whom there was no past history of treatment with steroids for more than six months. In 15 patients (58%), contrast-enhanced MR image revealed diffuse enhancement of the basal ganglia or intravascular enhancement. In no case were MRI findings normal. The primary mainfestations of neuropsychiatric lupus are multifocal ischemia or infarctions in the cerebral cortex, and subcortical and deep white matter, and the cerebral atrophy. Contrast-enhanced MR images also demonstrated diffuse enhancement of the basal ganglia and intravascular enhancement, both thought to be related to the congestion due to the stagnation of cerebral blood flow.

Kim, Jang-Wook; Kwon, Bae Ju; Lee, Seung-Ro; Hahm, Chang-Kok; Moon, Won Jin; Jeon, Eui Yong; Bae, Sang-Chul [Hanyang Univ. School of Medicine, Seoul (Korea, Republic of)

2000-12-01

82

MRI findings in a dog with kernicterus.  

Science.gov (United States)

A severe increase in total bilirubin coincided with a decline in neurologic status to comatose in a 9 yr old spayed female mixed-breed dog being treated for immune-mediated hemolytic anemia. MRI of the brain was performed to investigate potential causes for the neurologic signs. MRI revealed bilaterally symmetrical hyperintensities within the caudate nuclei, globus pallidus, thalamus, deep cerebellar nuclei, and cortical gray matter on T2-weighted and fluid-attenuated inversion recovery (FLAIR) sequences, which coincided with areas of bilirubin deposition and neuronal necrosis (kernicterus) identified on necropsy examination. This is the second case report of an adult dog exhibiting kernicterus, and the first report to document MRI findings associated with that condition. Kernicterus is an uncommonly reported complication of hyperbilirubinemia in dogs, but is potentially underreported due to difficulties in recognizing subtle lesions and distinguishing kernicterus from other potential causes of neurologic abnormalities with readily available antemortem tests. MRI may be helpful in supporting the diagnosis of kernicterus. PMID:23690488

Belz, Katie M; Specht, Andrew J; Johnson, Victoria S; Conway, Julia A

2013-01-01

83

Intracranial hemorrhage: ultrasound, CT and MRI findings  

International Nuclear Information System (INIS)

Intracranial hemorrhage is one of the most common causes of acute focal neurologic deficit in children and adults. Neuroimaging including ultrasonography (US), computer tomography (CT) and magnetic resonance imaging (MRI) is essential in the diagnosis of intracranial hemorrhage. Imaging findings should guide treatment. The highly variable appearance of an intracranial hemorrhage can be challenging. A thorough knowledge of hematoma evolution and US, CT and MR hematoma characteristics is mandatory for adequate interpretation of findings. The purpose of this review is (1) to summarize the imaging characteristics of intracranial hemorrhage on various imaging techniques and (2) to review the various types of intracranial hemorrhage, and their causes. (orig.)

84

Periarthritis of the shoulder-MRI findings  

International Nuclear Information System (INIS)

We examined MRI findings in patients with periarthritis of the shoulder. We excluded cuff tears, calcified tendinitis, instability of the shoulder, fracture and impingement syndrome of young patients. Subjects comprised 36 cases, 38 shoulders (25 men and 11 women), with an average age of 59.1 years (42-75). Scanning was performed on a Gyroscan T5-II 0.5-T (Philips). T1-weighted and T2-weighted sequences in the coronal oblique plane, T2-weighted sequences in the coronal sagittal plane and horizontal plane were taken. Twelve shoulders showed some change in the humeral heads. Degeneration of the rotator cuff was observed in 15 shoulders. Joint fluid collection was observed in the gleno-humeral joints of 15 shoulders, in the subacromial bursa of 11 shoulders and in the acromio-clavicular joints of 7 shoulders. Twenty four shoulders had fluid collection in the sheath of the long head of the biceps long tendon. Localized high signal area was observed around the inferior pouch in 11 shoulders. We studied the relationship between MRI findings and clinical symptoms. There was no significant relationship but the shoulders with night pain and severe contractures had a higher positive rate of joint fluid collection on MRI than the shoulders without night pain and with less contractures. (author)

85

Clinical and MRI findings of brucellar spondylodiscitis  

International Nuclear Information System (INIS)

Objective: The aim of this retrospective study was to report the clinical features and MR imaging findings of patients with brucellar spondylodiscitis. Materials and methods: Twenty-two patients with spondylodiscitis, recruited among 152 patients with brucellosis referred from the Department of Infectious Diseases. Patients were diagnosed based on positive clinical findings, ?1/160 titers of brucella agglutination tests and/or positive blood cultures. Magnetic resonance imaging (MRI) was performed to all of the patients with spondylodiscitis. Signal changes and enhancement of vertebral bodies, involvement of paravertebral soft tissues and epidural spaces, nerve root and cord compression and abscess formation were assessed. Results: All of the patients (n = 22; 7 F, 15 M) had ?1/160 titers of brucella agglutination test and blood culture was positive in 9. A great majority of the patients had involvement at only one vertebrae level (n = 21, 95.5%), whereas one patient (4.5%) had multilevel involvement. In MRI, eight patients had soft tissue involvement and three had abscess formation. All cases had vertebral and discal enhancement. Additionally epidural extension was detected in four cases, posterior longitudinal ligament (PLL) elevation in five cases and root compression in two cases. Conclusion: Brucella is still a public health problem in endemic areas. MRI is a highly sensitive and non-invasive imaging technique which should be first choice of imaging in the ead be first choice of imaging in the early diagnosis of spondylodiscitis

86

Periarthritis of the shoulder-MRI findings  

Energy Technology Data Exchange (ETDEWEB)

We examined MRI findings in patients with periarthritis of the shoulder. We excluded cuff tears, calcified tendinitis, instability of the shoulder, fracture and impingement syndrome of young patients. Subjects comprised 36 cases, 38 shoulders (25 men and 11 women), with an average age of 59.1 years (42-75). Scanning was performed on a Gyroscan T5-II 0.5-T (Philips). T1-weighted and T2-weighted sequences in the coronal oblique plane, T2-weighted sequences in the coronal sagittal plane and horizontal plane were taken. Twelve shoulders showed some change in the humeral heads. Degeneration of the rotator cuff was observed in 15 shoulders. Joint fluid collection was observed in the gleno-humeral joints of 15 shoulders, in the subacromial bursa of 11 shoulders and in the acromio-clavicular joints of 7 shoulders. Twenty four shoulders had fluid collection in the sheath of the long head of the biceps long tendon. Localized high signal area was observed around the inferior pouch in 11 shoulders. We studied the relationship between MRI findings and clinical symptoms. There was no significant relationship but the shoulders with night pain and severe contractures had a higher positive rate of joint fluid collection on MRI than the shoulders without night pain and with less contractures. (author)

Hirano, Mako; Nomura, Kazutoshi; Hashimoto, Noburo; Fukumoto, Tetsuya; Oshima, Suguru; Katahira, Kazuhiro [Kumamoto National Hospital (Japan)

1997-09-01

87

Localized Castleman's disease: CT and MRI findings  

International Nuclear Information System (INIS)

Objective: To study the CT and MRI findings of localized Castleman's disease (LCD). Methods: The CT (n=7) and MRI (n=2) appearance of LCD (n=7) confirmed by pathology and operation were retrospectively analyzed. Results Hyaline-vascular type(n=6) and plasma cell type (n=1) were confirmed by pathology in LCD (n=7). They were located in middle mediastinum (n=2), hilum pulmonis (n=l), posterior mediastinum (n=3), retro-peritoneum (n=1). Hyaline-vascular type focuses in CT scanning were manifested as round shape soft tissue masses, with homogeneous density, integrity envelope, distinct margin, and chaperonage arborizing and spot calcification. Marked persistent enhancement was apparent on contrast CT. MRI findings of hyaline-vascular type (n=2) was slightly isointense or hyperintense on T1WI, homogeneous hyperintense on T2WI, similar enhancement with CT after contrast. Plasma cell type focus were unhomogeneous density with abnormity necrosis, media and unhomogeneous enhancement after contrast. Conclusion: Marked persistent enhancement of LCD would be helpful to diagnosis and differential diagnosis in Castleman's disease. (authors)

88

Non-infectious ischiogluteal bursitis: MRI findings  

Energy Technology Data Exchange (ETDEWEB)

We wished to report on the MRI findings of non-infectious ischiogluteal bursitis. The MRI findings of 17 confirmed cases of non-infectious ischiogluteal bursitis were analyzed: four out of the 17 cases were confirmed with surgery, and the remaining 13 cases were confirmed with MRI plus the clinical data. The enlarged bursae were located deep to the gluteus muscles and postero-inferior to the ischial tuberosity. The superior ends of the bursal sacs abutted to the infero-medial aspect of the ischial tuberosity. The signal intensity within the enlarged bursa on T1-weighted image (WI) was hypo-intense in three cases (3/17, 17.6%), iso-intense in 10 cases (10/17, 58.9%), and hyper-intense in four cases (4/17, 23.5%) in comparison to that of surrounding muscles. The bursal sac appeared homogeneous in 13 patients (13/17, 76.5%) and heterogeneous in the remaining four patients (4/17, 23.5%) on T1-WI. On T2-WI, the bursa was hyper-intense in all cases (17/17, 100%); it was heterogeneous in 10 cases and homogeneous in seven cases. The heterogeneity was variable depending on the degree of the blood-fluid levels and the septae within the bursae. With contrast enhancement, the inner wall of the bursae was smooth (5/7 cases), and irregular (12/17 cases) because of the synovial proliferation and septation. Ischiogluteal bursitis can be diagnosed with MRI by its characteristic location and cystic appearance.

Cho, Kil Ho; Jang, Han Won [Yeungnam University College of Medicine, Daegu (Korea, Republic of); Lee, Sung Moon [Keimyung University College of Medicine, Daegu (Korea, Republic of); Lee, Young Hwan [Daegu Hyosung Catholic University College of Medicine, Daegu (Korea, Republic of); Suh, Kyung Jin [Suh and Joo MR Clinic, Seoul (Korea, Republic of); Kim, Sung Moon; Shin, Myung Jin [University of Ulsan College of Medicine, Seoul (Korea, Republic of)

2004-12-15

89

Assessing the accuracy and precision of musculoskeletal motion tracking using cine-PC MRI on a 3.0T platform.  

Science.gov (United States)

The rising cost of musculoskeletal pathology, disease, and injury creates a pressing need for accurate and reliable methods to quantify 3D musculoskeletal motion, fostering a renewed interest in this area over the past few years. To date, cine-phase contrast (PC) MRI remains the only technique capable of non-invasively tracking in vivo 3D musculoskeletal motion during volitional activity, but current scan times are long on the 1.5T MR platform (? 2.5 min or 75 movement cycles). With the clinical availability of higher field strength magnets (3.0T) that have increased signal-to-noise ratios, it is likely that scan times can be reduced while improving accuracy. Therefore, the purpose of this study is to validate cine-PC MRI on a 3.0T platform, in terms of accuracy, precision, and subject-repeatability, and to determine if scan time could be minimized. On the 3.0T platform it is possible to limit scan time to 2 min, with sub-millimeter accuracy (<0.33 mm/0.97°), excellent technique precision (<0.18°), and strong subject-repeatability (<0.73 mm/1.10°). This represents reduction in imaging time by 25% (42 s), a 50% improvement in accuracy, and a 72% improvement in technique precision over the original 1.5T platform. Scan time can be reduced to 1 min (30 movement cycles), but the improvements in accuracy are not as large. PMID:20863502

Behnam, Abrahm J; Herzka, Daniel A; Sheehan, Frances T

2011-01-01

90

Cardiac MRI findings of endomyocardial fibrosis (Loeffler's endocarditis) in a patient with rheumatoid arthritis.  

Science.gov (United States)

Loeffler's endocarditis and cardiac manifestations of the hypereosinophilic syndrome (HES) are rare and difficult to diagnose. We report a case of in a 36 year-old female with a history of rheumatoid arthritis with disabling dyspnea. The transthoracic echocardiogram demonstrated normal systolic cardiac functions and a left ventricular apical thrombus. However, using cardiovascular magnetic resonance (CMR) with inversion-recovery (IR) delayed enhancement, and cine steady-state free precession (SSFP) sequences, we were able to clearly demonstrate endocardial fibrosis, tissue inflammation, apical ventricular hypertrophy, and LV thrombus that correlate with clinical findings. We believe cardiac MRI is more useful than transthoracic echocardiography in the diagnosis and management of HES and ultimately it obviated the need for biopsy to confirm the diagnosis. PMID:25870507

Kharabish, Ahmed; Haroun, Dina

2015-04-01

91

MRI findings of osteomyelitis of the mandible  

International Nuclear Information System (INIS)

The purpose of this study was to evaluate the clinical significance of MRI findings of mandibular osteomyelitis. MR images of 24 patients with mandibular osteomyelitis (14 males and 10 females, average age of 49 years, range 16 to 80 years) were analyzed in relation to clinical findings and clinical outcome. The average duration of symptoms at the time of MR imaging was 17.2 months (range: 2 weeks to 12 years, median of 5 months). Seven patients (29%) were imaged within 1 month after the onset of symptoms. Patients were classified as ''cured'' and ''not cured'' based on the clinical outcome. Sixteen patients were ''cured'' and eight were ''not cured''. Characteristic MR findings were investigated on T1- weighted images (T1WI) and T2- weighted images with fat-suppression (T2WI). Characteristic MRI findings of mandibular osteomyelitis and the frequencies were signal changes in the bone marrow (low on T1WI and high on T2WI) in 24 patients (100%), defect of the cortical bone in 10 (42%), periosteal reaction in 8 (33%), widening of the bone width in 8 (33%), sequestrum in 1 (4%). Fourteen (58%) showed edematous change of surrounding muscles and seven (29%) showed abscess formation in the soft tissues. Six patients (25%) showed only signal changes in the bone marrow. Bone marrow signal change was categorized into 2 types. Fifteen (62.5%) showed homogenous signal changes on both T1WI and T2WI and the other 9 patients (37.5%) showed both high and low signal on T2WI in the areoth high and low signal on T2WI in the area showing a low signal on T1WI (heterogeneous type). These patterns were correlated with the occurrence of bone width change. The non-cured group significantly more frequently showed the heterogeneous type of bone marrow signal change and widening of bone width. The bone marrow signal change pattern and the presence of widening of bone width are indicators of treatment-resistant osteomyelitis of the mandible. (author)

92

CT and MRI findings of Kimura disease  

International Nuclear Information System (INIS)

Objective: To study the imaging features of Kimura disease to improve diagnostic ability prior to surgery. Methods: The clinical manifestations and CT and MR findings of 11 patients with histologically confirmed Kimura disease were retrospectively analyzed. All 11 tumors originated from (or involved) the parotid region in 7 cases, the maxillofacial region in 2 cases, the palate in one case and the groin in one case. Clinically, the lesions showed asymptomatic tumors with the mean clinical course over 2 years. The increase of eosinophilic granulocyte was found in all 11 cases. Results: On CT and MRI, 5 patients were single masses and others were multi-nodular masses. The smallest lesion was 6 mm x 3 mm, and the largest lesion was 60 mm x 34 mm. The lesions were almost ill-defined in the subcutaneous tissue, especially 10 locating underlying superficialfascia in head and neck. On CT, the lesions showed homogeneous hypodense to the muscle in 9 patients. The lesions appeared isointense signal or slightly hypointense on MR T1WI and slightly hyperintense on T2WI in 3 patients. All lesions revealed moderate or marked, and homogeneous or inhomogeneous enhancement. Regional lymph nodes (eight cases in the maxillofacial region and one in the groin) enlarged without necrosis and fusion, and with marked enhancement. Conclusion: The clinical and imaging findings of Kimura disease have some characteristics, the diagnosis can be made combined with the laboratoris can be made combined with the laboratory examination. (authors)

93

MRI and radiographic findings in Currarino's triad  

International Nuclear Information System (INIS)

Currarino's triad is a rare complex of a congential sacral bony abnormality, anorectal malformation and a presacral mass. Intractable constipation since birth is the leading symptom of this triad, which follows an autosomal dominant mode of heredity. We report conventional radiographic and MR findings in one family consisting of a mother and her two daughters. In all three cases, radiography revealed an abnormality of the os sacrum, the so-called scimitar sacrum. MR examination, undertaken next in our institution, was applied with T1-, T2- and proton density weighted sequences in all three orientations before and after i.v. application of gadolinium diethylene-triamine-pentaacetic acid (Gd-DTPA). In two patients we were able to diagnose the complete form of the triad and in one patient an incomplete form. In any case of a radiographically diagnosed scimitar sacrum in combination with constipation. Currarino's triad should be considered. MRI, as the method of choice, should be the next step to detect a presacral mass and any anomalies of the spinal canal. The importance of early recognition lies in the high morbidity and mortality rates resulting from this disorder. (orig.)

94

MRI findings in little leaguer's shoulder  

International Nuclear Information System (INIS)

Little leaguer's shoulder, a stress injury of the proximal humeral physis, should be considered in the differential diagnosis for an adolescent baseball player with shoulder pain, especially if the player is pitching regularly in a competitive environment. While roentgenographs may or may not be helpful, depending on the duration and severity of the injury, we report the MRI appearance of a case of little leaguer's shoulder. We found MRI helpful in diagnosing injury to the growth plate that was radiographically occult; furthermore, we were able to document the patient's progress with a follow-up MRI examination, which showed improvement with treatment. (orig.)

95

Functional cine MRI of the abdomen for the assessment of implanted synthetic mesh in patients after incisional hernia repair: initial results  

Energy Technology Data Exchange (ETDEWEB)

The aim of our study was to develop a method that allows the vizualiation and evaluation of implanted mesh in patients after incisional hernia repair with MRI. Furthermore, we assessed problems typically related with mesh implantation like adhesions and muscular atrophy. We enrolled 28 patients after incisional hernia repair. In 10 patients mesh implantation was done by laparoscopy (expanded polytetrafluoroethylene=ePTFE mesh) and in 18 by laparotomy (polypropylene mesh). Functional MRI was performed on a 1.5-T system in supine position. Sagittal and axial TrueFISP images of the entire abdomen were acquired with the patient repeatedly straining. Evaluation included: correct position and intact fixation of the mesh, furthermore visceral adhesions, recurrent hernia and atrophy of the rectus muscle. The ePTFE mesh was visible in all cases; the polypropylene mesh was not detectable. In seven of the ten ePTFE meshes the fixation was not intact; two recurrent hernias were detected. Twenty of 28 patients had intraabdominal adhesions. In 5 cases mobility of the abdominal wall was reduced, and 16 patients showed an atropy of the rectus muscle. Functional cine MRI is a suitable method for follow-up studies in patients after hernia repair. ePTFE meshes can be visualized directly, and typical complications like intestinal adhesions and abdominal wall dysmotility can be assessed reliably. (orig.)

Fischer, Tanja [Ludwig-Maximilians-University Munich, Department of Clinical Radiology, Munich (Germany); Ludwig-Maximilians-University Munich, Department of Clinical Radiology, Klinikum Innenstadt, Munich (Germany); Ladurner, Roland; Mussack, Thomas [Ludwig-Maximilians-University Munich, Department of Surgery and Traumatology, Klinikum Innenstadt, Munich (Germany); Gangkofer, Alexander; Reiser, Maximilian; Lienemann, Andreas [Ludwig-Maximilians-University Munich, Department of Clinical Radiology, Munich (Germany)

2007-12-15

96

Unilateral moya-moya disease: MRI findings  

Energy Technology Data Exchange (ETDEWEB)

The term 'moya-moya' refers to hypertrophic collateral circulation in the basal ganglia, in patients with stenosis or occlusion of the distal internal carotid artery at its bifurcation. Recent reports stress the value of MRI in the demonstration of both collateral circulation and cerebral infarction in patients with moya-moya disease. We wish to report a case of MRI demonstration of unilateral moya-moya vessels in a 10-year-old child. (orig.).

Wilms, G.; Marchal, G.; Fraeyenhoven, L. van; Demaerel, P.; Baert, A.L. (Leuven Univ. (Belgium). Dept. of Radiology); Casaer, P.; Elderen, S. van (Leuven Univ. (Belgium). Dept. of Pediatrics)

1989-11-01

97

Incidental MRI Findings of Acute Gadolinium Hypersensitivity  

OpenAIRE

A 13-year-old girl with a remote history of juvenile pilocytic astrocytoma developed acute onset flushing, tachycardia and shortness of breath immediately following administration of gadopentetate dimeglumine during routine brain MRI that subsided following intravenous diphenhydramine. A retrospective review of the MRI results revealed multiple areas of contrast enhancement of the face, consistent with observed urticaria. The patient received pretreatment medications prior to subsequent gadol...

Amene, C.; Yeh-nayre, L. A.; Dory, C. E.; Crawford, J. R.

2012-01-01

98

MRI findings in thoracic outlet syndrome  

International Nuclear Information System (INIS)

We discuss MRI findings in patients with thoracic outlet syndrome (TOS). A total of 100 neurovascular bundles were evaluated in the interscalene triangle (IS), costoclavicular (CC), and retropectoralis minor (RPM) spaces. To exclude neurogenic abnormality, MRIs of the cervical spine and brachial plexus (BPL) were obtained in neutral. To exclude compression on neurovascular bundles, sagittal T1W images were obtained vertical to the longitudinal axis of BPL from spinal cord to the medial part of the humerus, in abduction and neutral. To exclude vascular TOS, MR angiography (MRA) and venography (MRV) of the subclavian artery (SA) and vein (SV) in abduction were obtained. If there is compression on the vessels, MRA and MRV of the subclavian vessels were repeated in neutral. Seventy-one neurovascular bundles were found to be abnormal: 16 arterial-venous-neurogenic, 20 neurogenic, 1 arterial, 15 venous, 8 arterial-venous, 3 arterial-neurogenic, and 8 venous-neurogenic TOS. Overall, neurogenic TOS was noted in 69%, venous TOS in 66%, and arterial TOS in 39%. The neurovascular bundle was most commonly compressed in the CC, mostly secondary to position, and very rarely compressed in the RPM. The cause of TOS was congenital bone variations in 36%, congenital fibromuscular anomalies in 11%, and position in 53%. In 5%, there was unilateral brachial plexitis in addition to compression of the neurovascular bundle. Severe cervical spondylosis was noted in 14%, contributing to TOS sys was noted in 14%, contributing to TOS symptoms. For evaluation of patients with TOS, visualization of the brachial plexus and cervical spine and dynamic evaluation of neurovascular bundles in the cervicothoracobrachial region are mandatory. (orig.)

99

MRI Findings of Rectal Submucosal Tumors  

Energy Technology Data Exchange (ETDEWEB)

Rectal submucosal lesions encompass a wide variety of benign and malignant tumors involving the rectum. With optical colonoscopy, any mass-like protrusion covered by normal mucosa, whether the underlying process is intramural or extramural in origin, may be reported as a submucosal lesion. Whereas the assessment of submucosal lesions may be limited with performing optical colonoscopy, cross-sectional imaging such as CT, transrectal ultrasonography and MRI allows the evaluation of perirectal tissues and pelvic organs in addition to the entire thickness of the rectum, and so this is advantageous for the assessment of rectal submucosal tumors. Among these, MRI is the best investigative modality for soft tissue characterization. Therefore, knowledge of the MRI features of rectal submucosal tumors can help achieve accurate preoperative diagnoses and facilitate the appropriate management.

Kim, Hon Soul; Kim, Joo Hee; Lim, Joon Seok; Choi, Jin Young; Chung, Yong Eun; Park, Mi Suk; Kim, Myeong Jin; Kim, Ki Whang; Kim, Sang Kyum [Yonsei University Health System, Seoul (Korea, Republic of)

2011-08-15

100

MRI Findings of Rectal Submucosal Tumors  

International Nuclear Information System (INIS)

Rectal submucosal lesions encompass a wide variety of benign and malignant tumors involving the rectum. With optical colonoscopy, any mass-like protrusion covered by normal mucosa, whether the underlying process is intramural or extramural in origin, may be reported as a submucosal lesion. Whereas the assessment of submucosal lesions may be limited with performing optical colonoscopy, cross-sectional imaging such as CT, transrectal ultrasonography and MRI allows the evaluation of perirectal tissues and pelvic organs in addition to the entire thickness of the rectum, and so this is advantageous for the assessment of rectal submucosal tumors. Among these, MRI is the best investigative modality for soft tissue characterization. Therefore, knowledge of the MRI features of rectal submucosal tumors can help achieve accurate preoperative diagnoses and facilitate the appropriate management.

101

Radiographic and MRI findings in ochronosis  

International Nuclear Information System (INIS)

Purpose. Ochronotic arthropathy is the articular manifestation of alkaptonuria, a rare hereditary metabolic disease that leads to the deposition of homogentisinic acid particularly in the joints where it causes articular degeneration and inflammation. We studied the radiological patterns of the disorder using both traditional X rays both MRI and comparing the results obtained with the two techniques. Materials and methods. The study included five patients (4 males, 1 female, mean age 51 years); we studied the most frequently affected sites, the knee, the shoulder and the spine. As regards the conventional study we used a radiographic score which considered the state of the articular space and the presence of calcifications. MRI of the peripheral joints was performed on the most symptomatic site or, if asymptomatic, on the most severely affected site as established by radiography; in all cases T1- and T2 weighted sequences in the axial, sagittal and coronal planes were acquired. Results. Both the X-ray and MRI study revealed the typical alterations of ochronosis in the cases with a known diagnosis: articular space narrowing up to osseous ankylosis, calcifications, osteophytosis, reactive sclerosis of the articular surfaces; MRI was how evermore accurate. in identifying the alterations and revealing lesions not visible at conventional radiology, such as ligament lesions. In the case of newly diagnosed ochronotic arthropathy MRI proved valuable for its ability to detect proved valuable for its ability to detect alterations that are poorly appreciable at conventional radiology. Conclusions. Modern diagnostic imaging, above all MRI, allowed to identify the peculiar characteristic features of ochronosis and is fundamental both for the diagnosis and for differentiating ochronosis from other articular disorders

102

Measurement of coronary flow response to cold pressor stress in asymptomatic women with cardiovascular risk factors using spiral velocity-encoded cine MRI at 3 Tesla  

Energy Technology Data Exchange (ETDEWEB)

Background: Coronary sinus (CS) flow in response to a provocative stress has been used as a surrogate measure of coronary flow reserve, and velocity-encoded cine (VEC) magnetic resonance imaging (MRI) is an established technique for measuring CS flow. In this study, the cold pressor test (CPT) was used to measure CS flow response because it elicits an endothelium-dependent coronary vasodilation that may afford greater sensitivity for detecting early changes in coronary endothelial function. Purpose: To investigate the feasibility and reproducibility of CS flow reactivity (CSFR) to CPT using spiral VEC MRI at 3 Tesla in a sample of asymptomatic women with cardiovascular risk factors. Material and Methods: Fourteen asymptomatic women (age 38 years +- 10) with cardiovascular risk factors were studied using 3D spiral VEC MRI of the CS at 3 T. The CPT was utilized as a provocative stress to measure changes in CS flow. CSFR to CPT was calculated from the ratio of CS flow during peak stress to baseline CS flow. Results: CPT induced a significant hemodynamic response as measured by a 45% increase in rate-pressure product (P<0.01). A significant increase in CS volume flow was also observed (baseline, 116 +- 26 ml/min; peak stress, 152 +- 34 ml/min, P=0.01). CSFR to CPT was 1.31 +- 0.20. Test-retest variability of CS volume flow was 5% at baseline and 6% during peak stress. Conclusion: Spiral CS VEC MRI at 3 T is a feasible and reproducible technique for measuring CS flow in asymptomatic women at risk for cardiovascular disease. Significant changes in CSFR to CPT are detectable, without demanding pharmacologic stress

Maroules, Christopher D.; Peshock, Ronald M. (Dept. of Radiology, Univ. of Texas Southwestern Medical Center, Dallas, TX (United States)), e-mail: Ron.Peshock@UTSouthwestern.edu; Chang, Alice Y.; Kontak, Andrew (Dept. of Internal Medicine, Univ. of Texas Southwestern Medical Center, Dallas, TX (United States)); Dimitrov, Ivan; Kotys, Melanie (Dept. of Philips Medical Systems, Cleveland, OH (United States))

2010-05-15

103

CT and MRI findings of cardiac echinococcosis  

International Nuclear Information System (INIS)

Fifteen patients (8 males and 7 females, 15-56 years old) with primary or secondary hydatid disease involving the heart were examined by radiography, CT and/or MRI. MRI was done with a 1.5 T machine (Picker) in 11 cases and a 0.5 T machine (Philips) in 4 cases using ECG-gated T1- and T2-weighted spin-echo pulse sequences. Transaxial sections were combined with at least one more plane (coronal and/or sagittal) and intermediate views if the need for further information was anticipated. In 4 patients primary cardiac echinococcal cysts were found, localised to the left ventricle/pericardium/interventricular septum in 2 cases and to the left atrium/pericardium and right atrium/pericardium in 1 case each. In 11 of 15 cases there was secondary involvement of the heart by echinococcal cysts primarily arising in the lung parenchyma (n = 6), mediastinum (n = 3) and by transdiaphragmatic extension from the liver and abdomen (n = 2). CT was superior to MRI in visualising calcifications. However, ECG-gated MRI of cardiac hydatid disease appears to be the method of choice for specific diagnosis and exact assessment of hydatid cysts and their correlation with cardiac structures. (orig.)

104

MRI findings in a rottweiler with leukoencephalomyelopathy.  

Science.gov (United States)

A 22 mo old male rottweiler presented with a 1 mo progressive history of general proprioceptive ataxia and upper motor neuron tetraparesis. Neurologic examination was consistent with a lesion affecting the first through fifth cervical spinal cord segments. MRI disclosed bilaterally symmetric hyperintensities on T2-weighted (T2W) images in the crus cerebri and pyramidal tracts of the brain and the dorsal portion of the lateral funiculi of the cervical spinal cord. Fifty days after initial presentation, the dog was euthanized due to disease progression. Pathologic examination of the central nervous system (CNS) revealed a bilaterally symmetric chronic leukoencephalomyelopathy (LEM) consistent with previous reports of LEM in rottweilers. To the authors' knowledge, this is the first report to describe the MRI characteristics of LEM in the rottweiler. The topography of the changes observed with MRI paralleled the pathologic changes, which were widespread loss of myelin, decreased axon numbers, and astroglial proliferation. Consequently, MRI of the CNS of affected rottweilers may aid in establishing a presumptive antemortem diagnosis of LEM. PMID:23690496

Eagleson, Joseph S; Kent, Marc; Platt, Simon R; Rech, Raquel R; Howerth, Elizabeth W

2013-01-01

105

MRI Findings of Pericardial Fat Necrosis: Case Report  

Energy Technology Data Exchange (ETDEWEB)

Pericardial fat necrosis is an infrequent cause of acute chest pain and this can mimic acute myocardial infarction and acute pericarditis. We describe here a patient with the magnetic resonance imaging (MRI) findings of pericardial fat necrosis and this was correlated with the computed tomography (CT) findings. The MRI findings may be helpful for distinguishing pericardial fat necrosis from other causes of acute chest pain and from the fat-containing tumors in the cardiophrenic space of the anterior mediastinum.

Lee, Hyo Hyeok; Ryu, Dae Shick; Jung, Sang Sig; Jung, Seung Mun; Choi, Soo Jung; Shin, Dae Hee [Gangneung Asan Hospital, Ulsan University College of Medicine, Gangneung (Korea, Republic of)

2011-06-15

106

MRI findings in neuro-Behcet's disease  

International Nuclear Information System (INIS)

AIM: To evaluate the pattern and site of involvement in neuro-Behcet's disease (NBD). MATERIALS AND METHODS: Twenty-one patients with NBD were evaluated. Using 1.5T magnetic resonance imaging (MRI), T1-weighted axial and sagittal images, gadolinium enhanced axial and coronal images and T2-weighted axial images were obtained. RESULTS: The brainstem, basal ganglia, cerebral white matter, internal capsule, thalamus and spinal cord were involved in eighteen, nine, nine, seven, six and two patients, respectively. In nine patients with cerebral white matter involvement, four had subcortical involvement and three had periventricular involvement, in addition to two patients with focal deep white matter lesions. Among the brainstem lesions, pons involvement was seen in fourteen patients, all had ventrally located lesions, and nine had tegmental involvement. Midbrain involvement was seen in fourteen patients; the cerebral peduncle was involved in 11 of these. Five patients had brainstem atrophy: two cases were demonstrated at initial MRI, the other three cases were seen on follow-up MRI. Pyramidal signs, the most common neurological signs, were demonstrated in fourteen patients. Follow-up MRI was obtained 10 days to 20 months after the initial MRI in eight cases; all showed changes in size, shape and site of involvement. After gadolinium enhancement, thirteen patients demonstrated mottled non-confluent enhancement in the brainstem (eight patients), posterior limb of the internat patients), posterior limb of the internal capsule (three patients), pachymeninges (two patients) and spinal cord (two patients). CONCLUSION: NBD manifests a reversible course, but chronic NBD may result in brainstem atrophy. Characteristic involvement along the corticospinal tract is well correlated with neurological signs. Lee, S. H. et al. (2001)

107

Non-traumatic peroneal nerve palsy: MRI findings  

International Nuclear Information System (INIS)

Aim: To present magnetic resonance imaging (MRI) findings of non-traumatic peroneal nerve palsy and to evaluate the usefulness of MRI in patients with non-traumatic peroneal nerve palsy. Materials and methods: In a retrospective study, 11 consecutive patients presenting with peroneal nerve palsy were included. MR images of the lower leg and electrophysiological examinations were also reviewed. The cause of peroneal nerve palsy was determined on the basis of MRI findings and was evaluated using electrophysiological data. Nine patients with causative lesions detected on MRI, underwent surgery. Results: Clinical examination and electromyography (EMG) disclosed 11 peroneal lesions. MRI and EMG revealed three types of signal intensity change, i.e. deep peroneal nerve palsy type, common peroneal nerve palsy type, and superficial peroneal nerve palsy type. The MRI and EMG findings were in agreement in seven (65%) of the 11 study patients. In nine patients the causative lesions were identified using MRI, including ganglion cyst (n = 6), osteochondroma (n = 1), synovial cyst (n = 1), and aneurysm (n = 1). Conclusion: Ganglion cyst is the most common cause of non-traumatic peroneal nerve palsy. MRI offers a noninvasive method for obtaining useful information to assess, localize, and monitor peripheral peroneal nerve palsy

108

MRI findings in meningeal cysts of the vertebral column  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study was to demonstrate the MRI findings and to emphasise the contribution of MRI to the diagnosis of this rare pathology. MRI findings were evaluated according to a new classification that divides MCs into extradural cysts without (type 1) or with (type 2) spinal nerve root fibres and intradural cysts (type 3). Because of its high contrast resolution MRI can distinguish the three types of MC. The use of the different levels of signal intensity of the cyst and CSF in T2-weighted images to distinguish communicating from non-communicating MCs is illustrated. This diagnostic sign exploitats the signal loss due to flow phenomena of CSF pulsations on ungated sequences to reveal the communication of the MC with the SAS. We recommend MRI as the most sensitive and specific modality for the study of MCs. (orig.)

Chalkias, S.M. [Dept. of Radiology, AHEPA General Hospital of the Aristotelian Univ., Thessaloniki (Greece); Cova, M.A. [Dept. of Radiology, University Hospital of Trieste, Ospedale di Cattinara (Italy); Ricci, C. [Dept. of Radiology, University Hospital of Trieste, Ospedale di Cattinara (Italy); Magnaldi, S. [Dept. of Radiology, University Hospital of Trieste, Ospedale di Cattinara (Italy); Pozzi-Mucelli, R.S. [Dept. of Radiology, University Hospital of Trieste, Ospedale di Cattinara (Italy)

1993-10-01

109

Brain MRI findings of complex partial seizure in children  

International Nuclear Information System (INIS)

Twenty-two children(4 months to 17 year old) with a clinical diagnosis of complex partial seizure(CPS) were examined with a 0.5 T MRI scanner using spin-echo sequences. Eleven patients showed abnormal brain MRI findings; two had focal lesions with corresponding seizure foci on the EEG, one arising from temporal lobe(Hippocampal formation atrophy) and the other from the frontal lobe. Nine patients showed diffuse lesions with inconsistent seizure foci on EEG. The remaining 11 patients were normal on brain MRI; two of them had normal EEG findings and the others either focal or diffuse abnormalities on EEG

110

Solitary infantile choriocarcinoma of the liver: MRI findings  

International Nuclear Information System (INIS)

Infantile hepatic choriocarcinoma is a rare, highly malignant germ-cell tumour believed to result from a choriocarcinoma of the placenta that spreads to the child. Most infants present with a characteristic clinical picture of anaemia, hepatomegaly and precocious puberty. Imaging findings, including conventional MRI, may be non-specific. To improve the accuracy of diagnosis, we present the imaging findings of contrast-enhanced dynamic MRI in a 4.5-month-old boy with infantile hepatic choriocarcinoma. (orig.)

111

MRI findings in an adolescent with type I citrullinaemia  

Energy Technology Data Exchange (ETDEWEB)

Citrullinaemia is a rare inborn error of urea cycle metabolism. We describe the MRI findings in a 16-year-old boy with type I citrullinaemia during an episode of acute hyperammonaemic encephalopathy and compare them to his previous follow-up MRI studies. MRI revealed bilateral high signal intensity in the cingulate, perirolandic, parietal and temporoinsular cortex, the subcortical white matter and left thalamus. Diffusion-weighted imaging showed high signal intensity and low apparent diffusion coefficient values in the frontoparietal lobes. To our knowledge, MRI findings in an adolescent with type I citrullinaemia have not been previously reported. Since our patient's neuroradiological findings showed greater similarity to type II citrullinaemia, we think his brain injury during this acute episode was probably age-related and independent of the type of citrullinaemia. (orig.)

Longo, Daniela; Delfino, Luciana; Fariello, Giuseppe [Bambino Gesu Children' s Hospital, Department of Paediatric Radiology, Rome (Italy); Genovese, Elisabetta; Cannata, Vittorio [Bambino Gesu Children' s Hospital, Department of Medical Direction/Medical Physics, Rome (Italy); Deodato, Federica; Dionisi-Vici, Carlo [Bambino Gesu Children' s Hospital, Division of Metabolism, Department of Neuroscience, Rome (Italy); Goffredo, Bianca [Bambino Gesu Children' s Hospital, Laboratory, Rome (Italy)

2008-02-15

112

Arrhythmogenic right ventricular dysplasia: MRI findings  

Energy Technology Data Exchange (ETDEWEB)

Arrhythmogenic right ventricular dysplasia (ARVD) is a heart muscle disorder of unknown cause that is characterized pathologically by fibrofatty replacement of the right ventricular myocardium. Clinical manifestations include structural and functional malformations of the right ventricle, electrocardiographic abnormalities, and presentation with ventricular tachycardias with left bundle branch pattern or sudden death. The disease is often familial with an autosomal inheritance. In addition to right ventricular dilatation, right ventricular aneurysms are typical deformities of ARVD and they are distributed in the so-called ''triangle of dysplasia'', i. e., right ventricular outflow tract, apex, and infundibulum. Ventricular aneurysms at these sites can be considered pathognomonic of ARVD. Another typical hallmark of ARVD is fibrofatty infiltration of the right ventricular free wall. These functional and morphologic characteristics are relevant to clinical imaging investigations such as contrast angiography, echocardiography, radionuclide angiography, ultrafast computed tomography, and magnetic resonance imaging (MRI). Among these techniques, MRI allows the clearest visualization of the heart, in particular because the right ventricle is involved, which is usually more difficult to explore with the other imaging modalities. Furthermore, MRI offers the specific advantage of visualizing adipose infiltration as a bright signal of the right ventricular myocardium. MRI provides the most important anatomic, functional, and morphologic criteria for diagnosis of ARVD within one single study. As a result, MRI appears to be the optimal imaging technique for detecting and following patients with clinical suspicion of ARVD. (orig.) [German] Die arrhythmogene rechtsventrikulaere Dysplasie (ARVD), eine Herzmuskelerkrankung unklarer Aetiologie, ist pathologisch durch fettige Degeneration des rechtsventrikulaeren Myokards gekennzeichnet. Die klinischen Symptome umfassen strukturelle und funktionelle Malformationen des rechten Ventrikels, krankhafte elektrokardiographische Befunde und das Auftreten ventrikulaerer Tachykardien mit Linksschenkelblock oder ploetzlichem Herztod. Die Krankheit tritt familiaer gehaeuft auf und wird autosomal vererbt. Neben der rechtsventrikulaeren Dilatation stellen rechtsventrikulaere Aneurysmen typische Fehlbildungen bei ARVD dar. Sie sind im so genannten ''Dysplasiedreieck'', das heisst rechtem ventrikulaerem Ausflusstrakt, Herzspitze und Infundibulum, verteilt. Dort lokalisierte ventriku-laere Aneurysmen koennen als pathognomonisch fuer die ARVD angesehen werden. Ein weiteres typisches Merkmal der ARVD ist die fettige Degeneration der freien rechten Ventrikelwand. Diese funktionellen und strukturellen Charakteristika sind bei der klinischen Untersuchung mit bildgebenden Verfahren wie Kontrastangiographie, Echokardiographie, Radionuklidangiographie, ultraschneller Computertomographie und Magnetresonanztomographie (MRT) von Bedeutung. Unter diesen Verfahren erlaubt die MRT die deutlichste Darstellung des Herzens, insbesondere bei Beteiligung des rechten Ventrikels, der sich mit den anderen bildgebenden Methoden in der Regel schwerer untersuchen laesst. Darueber hinaus bietet die MRT den wesentlichen Vorteil der Darstellung der fettigen Degeneration als helles Signal im rechtsventrikulaeren Myokard. Die MRT liefert die wichtigsten anatomischen,m funktionellen und morphologischen Kriterien zur Diagnose einer ARVD in einem einzigen Untersuchungsgang. Daher scheint sie das beste bildgebende Verfahren zur Identifizierung und Nachsorge von Patienten mit klinischem Verdacht auf ARVD zu sein. (orig.)

Wall, E.E. van der; Bootsma, M.M.; Schalij, M.J. [Dept. of Cardiology, Leiden Univ. Medical Center, Leiden (Netherlands); Kayser, H.W.M.; Roos, A. de [Dept. of Radiology, Leiden Univ. Medical Center, Leiden (Netherlands)

2000-06-01

113

Pathological findings correlated with MRI in HIV infection  

International Nuclear Information System (INIS)

MRI forms an important part of the assessment of patients with HIV-related disease presenting with cerebral symptoms. Eleven formalin-fixed brains were studied at 0.5 T using T2- and T1-weighted sequences. In two cases of progressive multifocal leucoencephalopathy and one case each of toxoplasmosis and lymphoma, the extent of white matter abnormality seen on MRI corresponded broadly with that on pathological examination. In general, however, histological changes were more frequent than lesions on MRI. Cases in wich abnormalities were not seen with standard MRI included those with multiple tuberculous granulomata, multinucleate giant cells, microglial nodules, perivascular cuffing and cytomegalovirus inclusions. A common finding on MRI was punctate or patchy high signal in the basal ganglia on T2-weighted scans, seen in six cases. Corresponding histological changes included calcification of vessels with widened perivascular spaces, and mineralised neurones. (orig.)

114

See-saw nystagmus and brainstem infarction: MRI findings  

Science.gov (United States)

A patient with see-saw nystagmus had a lesion localized by Magnetic Resonance Imaging (MRI) to the paramedian ventral midbrain with involvement of the right interstitial nucleus of Cajal. This the first MRI study of see-saw nystagmus associated with a presumed brainstem vascular event. Our findings support animal and human studies suggesting that dysfunction of the interstitial nucleus of Cajal or its connections is central in this disorder.

Kanter, D. S.; Ruff, R. L.; Leigh, R. J.; Modic, M.

1987-01-01

115

Ossifying lipoma of the parapharyngeal space: CT and MRI findings  

International Nuclear Information System (INIS)

Ossifying lipomas independent of bone tissue are very rare. A literature review revealed that only few cases of ossifying lipoma independent of bone tissue have been reported. None of the cases have been reported in the international radiology literature. In addition, there are no reports concerning the MRI features of this entity. We describe CT and MRI findings in a case of ossifying lipoma of the parapharyngeal space. (orig.)

116

Ossifying lipoma of the parapharyngeal space: CT and MRI findings  

Energy Technology Data Exchange (ETDEWEB)

Ossifying lipomas independent of bone tissue are very rare. A literature review revealed that only few cases of ossifying lipoma independent of bone tissue have been reported. None of the cases have been reported in the international radiology literature. In addition, there are no reports concerning the MRI features of this entity. We describe CT and MRI findings in a case of ossifying lipoma of the parapharyngeal space. (orig.)

Minutoli, F.; Mazziotti, S.; Gaeta, M.; Vinci, S.; Blandino, A. [Inst. of Radiologic Sciences, University of Messina (Italy); Mastroeni, M. [Div. of Radiology, Messina (Italy)

2001-09-01

117

Measurement of ventricular volumes by cine magnetic resonance imaging in complex congenital heart disease  

International Nuclear Information System (INIS)

Along with the remarkable improvement in surgical results for complex congenital heart disease (CCHD) in recent years, it has become increasingly important for pediatric cardiologist and cardiovascular surgeons to evaluate ventricular volumes in CCHD accurately to develop a proper strategy for treating these patients. However, the validity of geometric formulas to derive volumes in various morphological types of abnormal ventricles like those in CCHD has been problematic. This study assessed the validity and usefulness of cine magnetic resonance imaging (MRI) for measuring right and left ventricular volumes using Simpson's rule in children with CCHD. Twenty-eight patients with CCHD (group A), children ranging in age from 4 months to 8 years (average 2.4 years) and 10 patients with morphologically normal ventricles (control; group B), ranging in age from 1 to 6 years (average 2.7 years) were evaluated. Cine MRI was performed by the GRASS methods (gradient recalled acquisition in steady state) at 0.5 T. The whole heart was encompassed by contiguous 7 or 10 mm transverse section. Ventricular volumes were calculated by adding luminal areas determined in each section at end-diastole and end-systole (EDV and ESV). Cine MRI findings of the right and left ventricular volumes were compared with those on ventriculogram. All cine MRI studies were considered diagnostic. Comparison of the RVEDV, RVESV, LVEDV and LVESV in both groups yielded a good correlation between cine MRI (Y) d a good correlation between cine MRI (Y) and ventriculography (X): RVEDV; Y=0.98X-0.49, r=0.98, RVESV; Y=0.89X+2.2, r=0.95, LVEDV; Y=0.97X+0.59, r=0.97, LVESV; Y=0.91X+0.56, r=0.95, Group B: RVEDV; Y=0.87X+4.9, r=0.93, RVESV; Y=0.91X+1.7, r=0.90, LVEDV; Y=1.1X-3.0, r=0.97, LVESV; Y=0.91X+0.6, r=0.93. These findigns indicate that cine MRI provides a suitable non-invasive means of quantifying right ventricular volume and left ventricular volumes in children with CCHD. (author)

118

Biochemical and MRI findings of Kallmann's syndrome.  

Science.gov (United States)

Kallmann's syndrome is a neuronal migration disorder characterised by anosmia/hyposmia and hypogonadotropic hypogonadism. We present a case of a 21-year-old man who was unable to sense smell since birth and who displayed non-development of secondary sexual characteristics for the past 10?years. Blood investigations showed low basal levels of serum follicle stimulating hormone (FSH), serum luteinising hormone (LH) and serum testosterone. After a gonadotropin releasing hormone challenge test there was a slight increase in serum FSH and serum LH, and after a human chorionic gonadotropin (HCG) challenge test the patient's serum testosterone level increased to 34 times that of his basal level. MRI of the brain showed absence of bilateral olfactory bulbs and sulcus with an apparently normal appearing pituitary gland, and bilateral loss of distinction between the gyrus rectus and medial orbital gyrus, thus confirming the diagnosis. The patient is on treatment with injection of HCG 2000?IU deep intramuscular twice a week and is on follow-up. PMID:25498112

Dash, Prafulla Kumar; Raj, Dinesh Harvey

2014-01-01

119

Membranous lipodystrophy: skeletal findings on CT and MRI  

International Nuclear Information System (INIS)

Membranous lipodystrophy, also known as Nasu-Hakola disease, is a rare hereditary condition with manifestations in the nervous and skeletal systems. The radiographic appearance of skeletal lesions has been well described in the literature. However, CT and MRI findings of lesions in the bone have not been documented to date. This report describes the radiographic, CT, MRI, and histopathologic skeletal findings in a case of membranous lipodystrophy. With corroborative pathologic findings, a diagnosis of membranous lipodystrophy on imaging allows for appropriate clinical management of disease manifestations. (orig.)

120

Renal MRI findings and their clinical associations in nephropathia epidemica: analysis of quantitative findings  

Energy Technology Data Exchange (ETDEWEB)

Morphologic renal magnetic resonance imaging (MRI) findings in patients with nephropathia epidemica (NE) were evaluated, and these findings were correlated with the clinical course of NE. Renal MRI was performed in 20 hospitalized NE patients during the acute phase of their disease. A repeat MRI study was made 5-8 months later. Renal parenchymal volume, renal length and parenchymal thickness were decreased in all patients in the repeat study. Edema/fluid collections were found bilaterally in 16 patients in the primary MRI study. Greater change in parenchymal volume, renal length and parenchymal thickness between the primary and the repeat MRI study as well as the presence of edema/fluid collections in the primary study evinced mild association with clinical fluid volume overload, high blood pressure level, inflammation, thrombocytopenia and severe clinical renal insufficiency. Change in parenchymal volume was associated with a severe clinical course more markedly than the other MRI findings. Measurable renal MRI changes occurred in every NE patient. The severity of the findings in MRI evinced mild association with clinical fluid volume overload, high blood pressure level, inflammation, thrombocytopenia and severe clinical renal insufficiency. Based on this study and our previous ultrasound (US) findings, we prefer US as the primary examination mode in NE patients. (orig.)

Paakkala, A. [University of Tampere, Medical School, Tampere (Finland); Tampere University Hospital, Department of Radiology, Tampere (Finland); Dastidar, P.; Ryymin, P. [Tampere University Hospital, Department of Radiology, Tampere (Finland); Huhtala, H. [University of Tampere, School of Public Health, Tampere (Finland); Mustonen, J. [University of Tampere, Medical School, Tampere (Finland); Tampere University Hospital, Department of Medicine, Tampere (Finland)

2005-05-01

121

Renal MRI findings and their clinical associations in nephropathia epidemica: analysis of quantitative findings  

International Nuclear Information System (INIS)

Morphologic renal magnetic resonance imaging (MRI) findings in patients with nephropathia epidemica (NE) were evaluated, and these findings were correlated with the clinical course of NE. Renal MRI was performed in 20 hospitalized NE patients during the acute phase of their disease. A repeat MRI study was made 5-8 months later. Renal parenchymal volume, renal length and parenchymal thickness were decreased in all patients in the repeat study. Edema/fluid collections were found bilaterally in 16 patients in the primary MRI study. Greater change in parenchymal volume, renal length and parenchymal thickness between the primary and the repeat MRI study as well as the presence of edema/fluid collections in the primary study evinced mild association with clinical fluid volume overload, high blood pressure level, inflammation, thrombocytopenia and severe clinical renal insufficiency. Change in parenchymal volume was associated with a severe clinical course more markedly than the other MRI findings. Measurable renal MRI changes occurred in every NE patient. The severity of the findings in MRI evinced mild association with clinical fluid volume overload, high blood pressure level, inflammation, thrombocytopenia and severe clinical renal insufficiency. Based on this study and our previous ultrasound (US) findings, we prefer US as the primary examination mode in NE patients. (orig.)

122

The MRI findings of skull tuberculosis: a case report  

International Nuclear Information System (INIS)

The incidence of skull tuberculosis is very rare, with only a few cases reported as a result of a simple radiography and computed tomographic findings. In this study, we report the magnetic resonance image (MRI) findings of a case of skull tuberculosis, which was confirmed histologically

123

Clinical and MRI Findings in Acute Cerebellitis  

OpenAIRE

Acute cerebellitis is an inflammatory syndrome characterized by cerebellar dysfunction with acute onset. Here, the clinical findings, conventional and diffusion-weighted MR imaging features of five cases are reported. The most common clinical findings were headache, vertigo, nausea and vomiting. Neurological examination revealed cerebellar ataxia, nystagmus, dysmetria and dysdiadokinesia. Analysis of the CSF showed an elevated protein content and pleocytosis. Bilateral cerebellar cortical inv...

Alkan, O?zlem; Tan, Meliha; Demi?rog?lu, Yusuf Ziya; Tokmak, Naime; Demi?r, S?enay; Yildirim, Tu?lin

2009-01-01

124

MRI findings of complete growth hormone deficiency  

Energy Technology Data Exchange (ETDEWEB)

Magnetic resonance (MR) imaging was performed on the pituitary gland of 20 children (age range, 2-11 years) with short stature due to growth hormone deficiency. Sixteen patients with multiple pituitary hormone deficiency showed disappearance of the pituitary stalk, disappearance of high signal area of the posterior pituitary, presence of ectopic pituitary, and decreased volume of the anterior pituitary. Many of them had a history of perinatal abnormalities such as asphyxia at delivery, breech delivery, and bradytocia. On the contrary, patients with isolated growth hormone deficiency presented no abnormal findings on MR images, and had no history of perinatal abnormalities. The findings of pituitary stalk separation syndrome suggested the presence of multiple hypopituitarism. (S.Y.).

Ichiba, Yozo [National Hospital of Okayama (Japan)

1995-10-01

125

Clinical and MRI Findings in Acute Cerebellitis  

Directory of Open Access Journals (Sweden)

Full Text Available Acute cerebellitis is an inflammatory syndrome characterized by cerebellar dysfunction with acute onset. Here, the clinical findings, conventional and diffusion-weighted MR imaging features of five cases are reported. The most common clinical findings were headache, vertigo, nausea and vomiting. Neurological examination revealed cerebellar ataxia, nystagmus, dysmetria and dysdiadokinesia. Analysis of the CSF showed an elevated protein content and pleocytosis. Bilateral cerebellar cortical involvement and leptomeningeal enhancement along the folia represent the most common imaging presentations. Diffusion- weighted MR imaging showed restricted diffusion in two patients. In one patient, diffusion- weighted MR imaging did not show restricted diffusion. All patients were treated medically. Additionally, external ventricular drainage was performed in one patient. Follow-up MR imaging revealed cerebellar atrophy in 1 patient and gliosis in 2 patients. Two patients completely resolved after medical therapy. In conclusion, brain MR imaging and diffusion- weighted MR imaging are valuable imaging methods in diagnosis of cerebellitis, assessment of complications and sequel lesions.

Özlem ALKAN

2009-12-01

126

MRI findings associated with luxatio erecta humeri  

International Nuclear Information System (INIS)

Luxatio erecta humeri is a rare type of inferior glenohumeral dislocation with a unique radiographic appearance; however, the magnetic resonance imaging findings associated with this dislocation have not been described in the radiology literature. The purpose of this study is to identify magnetic resonance imaging findings associated with this uncommon type of glenohumeral dislocation. The magnetic resonance imaging features of four patients with clinical and radiographic evidence of luxatio erecta humeri were reviewed retrospectively by two musculoskeletal-trained radiologists. The reported mechanism of injury in all four patients was falling. The MR imaging examinations were evaluated for the presence of rotator cuff and biceps tendon pathology, glenoid labrum pathology, joint capsule and glenohumeral ligament injury, fractures and bone marrow contusions, articular cartilage injury, and joint effusions. All four patients demonstrated pathology of the glenohumeral joint. Three of the four patients demonstrated rotator cuff tears, including large full thickness tears of the supraspinatus and infraspinatus tendons in two patients, and small full thickness tear of the supraspinatus tendon with partial thickness tear of the infraspinatus tendon in the third patient. In the two patients with large full thickness tears of the supraspinatus and infraspinatus tendons, one patient demonstrated tearing of the subscapularis tendon with dislocation of a partially torn long head dislocation of a partially torn long head of the biceps tendon, and the second patient demonstrated full thickness tearing of the intra-articular biceps tendon. All four patients demonstrated injuries to the glenoid labrum and both anterior and posterior bands of the inferior glenohumeral ligament. Contusions or fractures of the humeral head were seen in two of the patients. Three of the four patients demonstrated cartilage abnormalities including a focal cartilage defect in the anterior inferior glenoid in one patient, and cartilage surface irregularity of the glenoid in the other two patients. Common magnetic resonance imaging findings in patients with a prior luxatio erecta humeri dislocation include rotator cuff tears, injury to the glenoid labrum, and injury to both the anterior and posterior bands of the inferior glenohumeral ligament. These findings are compatible with the mechanism of dislocation in luxatio erecta, and noting these findings on magnetic resonance imaging may suggest that the patient has sustained a prior inferiorly directed glenohumeral dislocation such as luxatio erecta. (orig.)

127

MRI findings associated with luxatio erecta humeri  

Energy Technology Data Exchange (ETDEWEB)

Luxatio erecta humeri is a rare type of inferior glenohumeral dislocation with a unique radiographic appearance; however, the magnetic resonance imaging findings associated with this dislocation have not been described in the radiology literature. The purpose of this study is to identify magnetic resonance imaging findings associated with this uncommon type of glenohumeral dislocation. The magnetic resonance imaging features of four patients with clinical and radiographic evidence of luxatio erecta humeri were reviewed retrospectively by two musculoskeletal-trained radiologists. The reported mechanism of injury in all four patients was falling. The MR imaging examinations were evaluated for the presence of rotator cuff and biceps tendon pathology, glenoid labrum pathology, joint capsule and glenohumeral ligament injury, fractures and bone marrow contusions, articular cartilage injury, and joint effusions. All four patients demonstrated pathology of the glenohumeral joint. Three of the four patients demonstrated rotator cuff tears, including large full thickness tears of the supraspinatus and infraspinatus tendons in two patients, and small full thickness tear of the supraspinatus tendon with partial thickness tear of the infraspinatus tendon in the third patient. In the two patients with large full thickness tears of the supraspinatus and infraspinatus tendons, one patient demonstrated tearing of the subscapularis tendon with dislocation of a partially torn long head of the biceps tendon, and the second patient demonstrated full thickness tearing of the intra-articular biceps tendon. All four patients demonstrated injuries to the glenoid labrum and both anterior and posterior bands of the inferior glenohumeral ligament. Contusions or fractures of the humeral head were seen in two of the patients. Three of the four patients demonstrated cartilage abnormalities including a focal cartilage defect in the anterior inferior glenoid in one patient, and cartilage surface irregularity of the glenoid in the other two patients. Common magnetic resonance imaging findings in patients with a prior luxatio erecta humeri dislocation include rotator cuff tears, injury to the glenoid labrum, and injury to both the anterior and posterior bands of the inferior glenohumeral ligament. These findings are compatible with the mechanism of dislocation in luxatio erecta, and noting these findings on magnetic resonance imaging may suggest that the patient has sustained a prior inferiorly directed glenohumeral dislocation such as luxatio erecta. (orig.)

Krug, David K.; Vinson, Emily N.; Helms, Clyde A. [Duke University Medical Center, Department of Radiology, Box 3808, Durham, NC (United States)

2010-01-15

128

Cortical dysplasia : MRI findings according to the pathological grading  

International Nuclear Information System (INIS)

The purpose of this study is to describe the MRI findings of cortical dysplasia (CD) according to pathological grading. MRI findings in 24 patients with pathologically proven CD were retrospectively reviewed and were described according to their histologic grading. The group consisted of 11 men and 13 women, and their median age was 21.4 (range, 5 to 41) years. Histologic findings were assigned one of three grades : Grade I (dyslamination of cortical layers only) ; Grade II (additional dysplastic neurons); or Grade III (additional balloon cells). T1 and T2W spin-echo MR images were obtained and were evaluated with specific reference to detection rate, location of the anomaly, the presence or absence of prolonged T2 relaxation in the underlying white matter, and configuration of the dysplastic cortex. Nine patients were found to be suffering from grade I CD, seven from grade II, and eight from grade III. MRI findings were abnormal in 58% of cases (14/24); three of these were grade I, four were grade II, and seven were grade III. Among these 14 patients, four had the lesion in the frontal lobe; five, in the temporal lobe; one, in the parietal lobe; two, in the sylvian fissure area, and two with tuberous sclerosis and multiple lesions. Of twelve patients with cortical dysplasia other than tuberous sclerosis, as seen on MRI, six showed poor gray-white matter differentiation, and six showed cortical thickening; this ranged from 7-10 mm in thickness with irregular, bumpy co0 mm in thickness with irregular, bumpy cortical surfaces. Areas of prolonged T2 relaxation in the underlying white matter were present in six patients. MRI findings were abnormal in 58 % of CD patients. The higher the pathological grading, the higher the detection rate of CD on MRI. To increase the detectability of slight cortical dysplasia, technical development, including new MR sequences or imaging methods, is needed (author). 21 refs., 5 figs

129

Masticator space lesions: MRI and CT findings  

International Nuclear Information System (INIS)

We evaluated the MR and CT findings of the masticator space lesions in order to identify the differences among the malignant and benign tumors and infectious conditions. MR and CT findings in 46 cases with proven masticator space lesions were reviewed retrospectively. We analysed the involvement of masticator muscles, adjacent spaces, orbit and intracranium, homogeneity, necrosis, cystic changes, growth patterns, calcifications, enhancement patterns, MR signal intensity, and CT attenuation. Among the 29 cases of malignant tumors, seven cases were mandibular tumors including four chondrosarcomas, and 22 cases were extramandibular tumors. Malignant tumors of mandibular origin showed large masses with severe bone destruction and epicenter of mandible. Extramandibular malignant tumors showed the epicenter out of the mandible and less severe bone destruction than mandibular tumors. Among the nine benign tumors, four cases were ameloblastomas which showed the well-defined masses and the expansion of the mandible, and four cases were extramandibular tumors which showed well-marginated extramandibular masses with no bone destruction. Among the eight infectious conditions, five cases were mandibular osteomyelitis with or without abscess formations, and the other three cases were infections from adjacent soft tissue or limited to the soft tissue. By careful observations of growth patterns, involvement of the masticator and adjacent spaces, bone changes, and epicenter of the leses, bone changes, and epicenter of the lesions, one can discriminate a mandibular lesion from an extramandibular lesion. With this approach, it is thought to be easier to suggest a diagnosis among a wide spectrum of masticator lesions

130

MRI findings of traumatic spinal subdural hematoma  

International Nuclear Information System (INIS)

To describe the MR imaging findings of traumatic spinal subdural hematoma. We retrospectively reviewed the MR images of six patients, with symptoms of acute spinal cord or cauda equena compression after trauma, together with spinal subdural hematoma. We analyzed the extent, location, configuration and signal intensity of the lesions. In five of sex cases, hematomas were distributed extensively throughout the thoracolumbosacral or lumbosacral spinal levels. In five cases they were located in the dorsal portion of the thecal sac, and in one case, in the ventral portion. On axial images, hematomas showed a concave or convex contour, depending on the amount of loculated hematoma. A lobulated appearance was due to limitation of free extension of the hematoma within the subdural space at the lateral sites (nerve root exist zone) at whole spine levels, and at the posteromedian site under lumbar 4-5 levels. In cases of spinal subdural hematoma, the lobulated appearance of hematoma loculation in the subdural space that bounds the lateral sites at al spinal levels and at the posteromedian site under L4-5 levels is a characteristic finding. (author)

131

CT and MRI findings in HAM  

International Nuclear Information System (INIS)

The findings of the spinal MR imagings and the CT myelography of 5 cases with HTLV-I associated myelopathy (HAM) were presented. One case who showed transverse myelopathy with a multiple sclerosis-like abrupt onset showed spinal-cord swelling at the early stage on CT myelography; its disappearance was documented 4 months after corticosteroid therapy. The other 4 cases, all with slowly progressive myelopathy, clinically revealed spinal-cord atrophy, especially at the thoracic level, on MR imagings. The degree of spinal-cord atrophy seemed not have any correlation with the clinical and laboratory data or with the corticosteroid therapy. The clinical entity of HAM has not yet been determined, and its relationship with tropical spastic paraparesis (TSP) as well as that with some form of multiple sclerosis is controversial. The neuroradiological findings of MR imaging and CT myelography, including spinal-cord swelling at the early stage, in a case diagnosed as HAM with atypical clinical features or as spinal-cord atrophy in typical chronic cases might contribute to its resolution. (author)

132

Reliability of MRI findings in candidates for lumbar disc prosthesis  

International Nuclear Information System (INIS)

Limited reliability data exist for localised magnetic resonance imaging (MRI) findings relevant to planning of treatment with lumbar disc prosthesis and later outcomes. We assessed the reliability of such findings in chronic low back pain patients who were accepted candidates for disc prosthesis. On pretreatment MRI of 170 patients (mean age 41 years; 88 women), three experienced radiologists independently rated Modic changes, disc findings and facet arthropathy at L3/L4, L4/L5 and L5/S1. Two radiologists rerated 126 examinations. For each MRI finding at each disc level, agreement was analysed using the kappa statistic and differences in prevalence across observers using a fixed effects model. All findings at L3/L4 and facet arthropathy at L5/S1 had a mean prevalence <10% across observers and were not further analysed, ensuring interpretable kappa values. Overall interobserver agreement was generally moderate or good (kappa 0.40-0.77) at L4-S1 for Modic changes, nucleus pulposus signal, disc height (subjective and measured), posterior high-intensity zone (HIZ) and disc contour, and fair (kappa 0.24) at L4/L5 for facet arthropathy. Posterior HIZ at L5/S1 and severely reduced subjective disc height at L4/L5 differed up to threefold in prevalence between observers (p < 0.0001). Intraobserver agreement was mostly good or very good (kappa 0.60-1.00). In candidates for disc prosthesis, mostly moderate interobserver agreement is expected for localised MRI findings. (orig.)cted for localised MRI findings. (orig.)

133

Investigation of MRI findings of Tolosa-Hunt syndrome  

International Nuclear Information System (INIS)

Objective: To investigate Mill findings of Tolosa-Hunt syndrome and evaluate the role of MRI in diagnosis and differential diagnosis. Methods: Seventeen cases of Tolosa-Hunt syndrome, confirmed by clinical follow-up, were studied. MRI scanning of the brain and thin-slice MilI scanning of the cavernous sinus combined with contrast scanning were performed and compared with each other in all cases. Results: Enlarged cavernous sinus was found in thin-slice MRI combined with contrast scanning in all 17 cases, which showed isointense or mildly hypointense on both T1-weighted and T2-weighted images and markedly homogeneous enhancement on postcontrast T1-weighted imaging. Thin-slice MRI also showed the abnormalities of the superior orbital fissure in three cases, of the orbital apex in one case, and of both the superior orbital fissure and the orbital apex in three cases. Cavernous sinus segment of the internal carotid artery, encircled by the lesion was seen in six patients and localized narrowing of it was observed in four eases. However, abnormal appearances of the cavernous sinus were demonstrated in only eleven patients on MRI scanning of the brain. Therefore, thin-slice Mill combined with contrast scanning was superior to Mill scanning of the brain in evaluation of Tolosa-Hunt syndrome (?2=4.17, P<0.05). Conclusion: Compared with MRI scanning of the brain, thin-slice MRI scanning of the cavernous sinus combined with contrast e cavernous sinus combined with contrast scanning could better reveal the characteristic findings of Tolosa-Hunt syndrome, contributing to diagnosis and differential diagnosis as well as follow-up. (authors)

134

MRI findings of hydroxyapatite orbital implants  

International Nuclear Information System (INIS)

To assess MR findings of hydroxyapatite orbital implants and their usefulness for the evaluation of fibrovascular ingrowth. MR images of 32 hydroxyapatite orbital implants were obtained six months after implantation surgery. We retrospectively analysed MR images for signal intensity and contrast enhancement in both central and peripheral zones of the implants. The degree of contrast enhancement in an implant was compared with that of the temporalis muscle on contrast enhanced fat suppressed T1-weighted images. On T1-weighted images, implants showed a higher signal intensity than that of the vitreous body in the opposite globe. All implants showed peripheral contrast enhancement, densely enhanced in 30 cases and faintly in two. Three implants showed dense central contrast enhancement, and in the remainder, enhancement was similar to that of gray matter. On T2-weighted images, bright signal intensity was noted in 29 implants, focally in 19 and diffusely in ten. In most cases, areas of peripheral iso- to low signal intensity on T2-weighted images corresponded well with the contrast-enhanced area on T1-weighted images. At six months of the surgery, Gd-enhanced MR imaging was useful for the evaluation of fibrovascular ingrowth in hydroxyapatite orbital implants

135

Useful MRI findings for differential diagnosis of sublingual mass lesions  

International Nuclear Information System (INIS)

The purpose of this study is to identify useful MRI findings for differentiating sublingual mass lesions. MR images of 29 patients with sublingual swelling were retrospectively reviewed. Patients were categorized into 4 groups according to their final diagnoses: cysts, benign tumors, inflammation and malignant tumors. Clinical symptoms and MRI findings of the patients in each diagnostic category were investigated. Of 29 patients, 6 had benign tumors, 6 had ranula, 6 had inflammation, 11 had malignant tumors. Eighteen patients (62%) were correctly diagnosed as one of 4 disease categories by clinical findings alone. Signal intensity of lesions compared to the muscle and the normal sublingual space (SLS) was not characteristic for any of the diagnostic categories. Only ranulas showed homogenous signal intensity within the lesion on T2 images. Hemangiomas were easily diagnosed by the characteristic contour and architecture including flow void. All lesions with ragged boundaries were either inflammatory or malignant masses. The lesions with ragged boundaries accompanied by expansion of the SLS were inflammatory masses. The lesions with smooth boundaries and a capsule-like rim were either cysts or benign tumors. Utilizing these MRI findings, 25 of 29 patients (86%) were correctly categorized into one of 4 diagnostic categories. Four lesions without a capsule-like rim confined within SLS could not be correctly categorized. These were 2 cases of inflammatory mass and 2 cases 2 cases of inflammatory mass and 2 cases of malignant salivary gland tumor. MRI findings were efficient for differentiation of sublingual mass lesions. However, some cases of malignant salivary gland tumor originating from the sublingual gland could not be differentiated on MRI findings from cases of chronic inflammation. (author)

136

Useful MRI findings for differential diagnosis of sublingual mass lesions  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study is to identify useful MRI findings for differentiating sublingual mass lesions. MR images of 29 patients with sublingual swelling were retrospectively reviewed. Patients were categorized into 4 groups according to their final diagnoses: cysts, benign tumors, inflammation and malignant tumors. Clinical symptoms and MRI findings of the patients in each diagnostic category were investigated. Of 29 patients, 6 had benign tumors, 6 had ranula, 6 had inflammation, 11 had malignant tumors. Eighteen patients (62%) were correctly diagnosed as one of 4 disease categories by clinical findings alone. Signal intensity of lesions compared to the muscle and the normal sublingual space (SLS) was not characteristic for any of the diagnostic categories. Only ranulas showed homogenous signal intensity within the lesion on T2 images. Hemangiomas were easily diagnosed by the characteristic contour and architecture including flow void. All lesions with ragged boundaries were either inflammatory or malignant masses. The lesions with ragged boundaries accompanied by expansion of the SLS were inflammatory masses. The lesions with smooth boundaries and a capsule-like rim were either cysts or benign tumors. Utilizing these MRI findings, 25 of 29 patients (86%) were correctly categorized into one of 4 diagnostic categories. Four lesions without a capsule-like rim confined within SLS could not be correctly categorized. These were 2 cases of inflammatory mass and 2 cases of malignant salivary gland tumor. MRI findings were efficient for differentiation of sublingual mass lesions. However, some cases of malignant salivary gland tumor originating from the sublingual gland could not be differentiated on MRI findings from cases of chronic inflammation. (author)

Ida, Mizue; Kurabayashi, Tohru; Yoshino, Norio; Tetumura, Akemi; Honda, Eiichi; Ohbayashi, Naoto; Sasaki, Takehito; Enomoto, Shoji; Amagasa, Teruo [Tokyo Medical and Dental Univ. (Japan). Graduate School

2001-06-01

137

Purulent meningitis with unusual diffusion-weighted MRI findings  

International Nuclear Information System (INIS)

We describe unusual findings obtained by diffusion-weighted magnetic resonance imaging (MRI) in a patient with acute purulent meningitis caused by penicillin-resistant Streptococcus pneumoniae. Along cerebral convexities and the Sylvian fissure, multiple small intense lesions showed high signal intensity in these sequences. This may be the first report of diffusion-weighted in purulent meningitis

138

CT and MRI findings of Madelung syndrome  

International Nuclear Information System (INIS)

Objective: To determine the CT and MR findings of Madelung syndrome. Methods: Five cases of Madelung syndrome were collected in our hospital from February 2006 to June 2009, including 3 cases of type ? Madelung syndrome and 2 cases of type ? Madelung syndrome. The 5 cases were all examined by CT, meanwhile 1 case by CT enhancement scanning and 2 cases by MR. The clinical characteristics and imaging manifestations were analyzed. Results: CT and MR images in 3 patients of type ? Madelung syndrome displayed fat accumulation within the subcutaneous tissue of the upper trunk and deep layer tissue of neck. The diffuse masses were located around the neck, upper chest and shoulders, which were called 'horse collar' and 'buffalo hump'. The other 2 cases of type ? Madelung syndrome displayed fat thickening within the subcutaneous tissue of the proximal extremities, anterior chest wall, showing special appearance of 'vigorous sailor'. All the 5 patients showed fat deposit within the subcutaneous tissue of the anterior rectus abdominis, inguina and fat accumulation within the scrotum. CT showed proliferated fat at the subcutaneous tissue of the involved regions. The CT value of proliferated fat were between - 30 and -70 HU. The proliferated fat tissue all could be displayed on MR T1WI, T2WI and T2WI fat suppression sequence, with typical hypointensity on T1WI and hyperintensity on T2WI, hypointensity on fat-suppression sequence and fibrous septation presenting among fat tissue. Conclusion: Combination with the history of long-term alcohol abuse, the Madelung syndrome could be diagnosed by CT and MR, which had great value in the surgical planning for identifying the extent of disease. (authors)

139

Accuracy of MRI findings in chronic lateral ankle ligament injury: Comparison with surgical findings  

International Nuclear Information System (INIS)

Aim: To evaluate the accuracy of magnetic resonance imaging (MRI) findings in chronic lateral ankle ligament injury in comparison with that of surgical findings. Materials and methods: Forty-eight cases (25 men, 23 women, mean age 36 years) of clinically suspected chronic ankle ligament injury underwent MRI studies and surgery. Sagittal, coronal, and axial, T1-weighted, spin-echo, proton density and T2-weighted, fast spin-echo images with fat saturation were obtained in all patients. MRI examinations were read in consensus by two fellowship-trained academic musculoskeletal radiologists who evaluated the lateral ankle ligaments, including the anterior talofibular ligament (ATFL) and calcaneofibular ligament (CFL) without clinical information. The results of the MRI studies were then compared with the surgical findings. Results: The MRI findings of ATFL injury showed a sensitivity of detection of complete tears of 75% and specificity of 86%. The sensitivity of detection of partial tears was 75% and the specificity was 78%. The sensitivity of detection of sprains was 44% and the specificity was 88%. Regarding the MRI findings of CFL injury, the sensitivity of detection of complete tears was 50% and the specificity was 98%. The sensitivity of detection of partial tear was 83% and the specificity was 93%. The sensitivity of detection of sprains was 100% and the specificity was 90%. Regarding the ATFL, the accuracies of detection were 88, 58, 77, and 85% for no injury, sprare 88, 58, 77, and 85% for no injury, sprain, partial tear, and complete tear, respectively, and for the CFL the accuracies of detection were 90, 90, 92, and 96% for no injury, sprain, partial tear, and complete tear, respectively. Conclusions: The diagnosis of a complete tear of the ATFL on MRI is more sensitive than the diagnosis of a complete tear of the CFL. MRI findings of CFL injury are diagnostically specific but are not sensitive. However, only normal findings and complete tears were statistically significant between ATFL and CFL (p < 0.001).

140

MRI Findings of Brucellar Spondylitis: A Case Report  

Energy Technology Data Exchange (ETDEWEB)

Brucellosis is a systemic infectious disease, and musculoskeletal involvement is a frequent complication. Particularly, spondylitis is a common involvement. However, early diagnosis of brucellar spondylitis is often difficult due to non-specific clinical symptoms and long latent period. Especially in Korea, where tuberculosis is an endemic disease, differentiation between tuberculous and brucellar spondylitis is clinically and radiologically more challenging. A 59-year-old male cattle farmer, who presented with non-specific back pain, had spondylitis on magnetic resonance imaging (MRI), and serologic test finally confirmed brucellar spondylitis. Therefore, we report a case of a rather rare disease in Korea, brucellar spondylitis with a review of MRI findings.

Kim, Jin Woo; Kim, Myung Soon; Kim, Young Ju [Dept. of Radiology, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, Wonju (Korea, Republic of)

2013-03-15

141

Scimitar syndrome: complete anatomical and functional diagnosis with gadolinium-enhanced and velocity-encoded cine MRI  

Energy Technology Data Exchange (ETDEWEB)

We report an asymptomatic 8-year-old girl with anomalous pulmonary venous connection to the IVC and systemic arterial supply (scimitar syndrome). We present for the first time a description of gadolinium-enhanced 3D MR angiography that provided concurrent non-invasive complete anatomical (arterial and venous supply) and 'functional' (calculation of left-to-right shunt using phase-contrast-MRI performed in the ascending aorta, main pulmonary artery and anomalous pulmonary vein) diagnosis, avoiding the need for more traditional invasive techniques. As the shunt quantification was less than 2:1, conservative management was decided upon. (orig.)

Marco de Lucas, Enrique; Canga, Ana; Sadaba, Pablo; Otero, Macarena [Department of Radiology, Hospital Universitario Marques de Valdecilla, Santander (Spain); Martin-Duran, Rafael [Department of Cardiology, Hospital Universitario Marques de Valdecilla, Santander (Spain); Cerezal, Luis [Department of Radiology, Instituto Radiologico Cantabro, Clinica Mompia, Mompia, Cantabria (Spain)

2003-10-01

142

Scimitar syndrome: complete anatomical and functional diagnosis with gadolinium-enhanced and velocity-encoded cine MRI  

International Nuclear Information System (INIS)

We report an asymptomatic 8-year-old girl with anomalous pulmonary venous connection to the IVC and systemic arterial supply (scimitar syndrome). We present for the first time a description of gadolinium-enhanced 3D MR angiography that provided concurrent non-invasive complete anatomical (arterial and venous supply) and 'functional' (calculation of left-to-right shunt using phase-contrast-MRI performed in the ascending aorta, main pulmonary artery and anomalous pulmonary vein) diagnosis, avoiding the need for more traditional invasive techniques. As the shunt quantification was less than 2:1, conservative management was decided upon. (orig.)

143

Necrotizing fasciitis: unreliable MRI findings in the preoperative diagnosis  

Energy Technology Data Exchange (ETDEWEB)

The authors present two cases of necrotizing fasciitis (NF), one case of dermatomyositis and one case of posttraumatic muscle injury, which have similar magnetic resonance imaging findings in terms of skin, subcutaneous fat, superficial and deep fasciae and muscle involvement. These cases highlight the need for cautious interpretation of magnetic resonance imaging (MRI) findings, for they are nonspecific and the preoperative decision should be based mostly on the evolution of the clinical status.

Arslan, Arzu E-mail: arzuarslan@netscape.net; Pierre-Jerome, Claude; Borthne, Arne

2000-12-01

144

Necrotizing fasciitis: unreliable MRI findings in the preoperative diagnosis  

International Nuclear Information System (INIS)

The authors present two cases of necrotizing fasciitis (NF), one case of dermatomyositis and one case of posttraumatic muscle injury, which have similar magnetic resonance imaging findings in terms of skin, subcutaneous fat, superficial and deep fasciae and muscle involvement. These cases highlight the need for cautious interpretation of magnetic resonance imaging (MRI) findings, for they are nonspecific and the preoperative decision should be based mostly on the evolution of the clinical status

145

Spongiform leucoencephalopathy after inhaling heroin vapor: CT and MRI findings  

International Nuclear Information System (INIS)

Objective: To explore CT and MRI features of spongiform leucoencephalopathy after inhaling 'heroin' pyrolysate, and to improve the diagnostic ability of the disease. Methods: Four patients, which inhaled heroin vapor, received the CT or MRI pre- and post-contrast scanning. MR sequences included conventional SE T1WI, T2WI, fluid attenuation inverse recover (FLAIR), and MRS. Results: All 4 cases had similar symmetrical lesions involving the cerebellum, lateral brainstem, cerebral peduncles, posterior limbs of internal capsule, splenium of corpus callosum, medial lemniscuses, and posterior cerebral white mattes without enhancement. The lesions showed hypodense on CT and hypointense on T1WI, hyperintense on T2WI and FLAIR. Cerebellar lesions were more serious than cerebral one, and the parieto-occipital lesions were serious than frontal one. MRS showed that the abnormalities in the white matter were degenerative changes, not necrosis. Conclusion: CT and MRI findings of this diseases are characteristic. Combined with the history, the disease can be diagnosed

146

Clinical features and MRI findings of blow-out fracture  

International Nuclear Information System (INIS)

Precise anatomical understanding of orbital blow-out fracture lesions is necessary for the treatment of patients. Retrospectively, MRI findings were compared with the clinical features of pure type blow-out fractures and the efficacy of MRI in influencing a decision for surgical intervention was evaluated. Eighteen child (15 boys, 3 girls) cases were evaluated and compared with adult cases. The patients were classified into three categories (Fig.1) and two types (Fig.2) in accordance with the degree of protrusion of fat tissue. The degree of muscle protrusion also was divided into three categories (Fig. 3). Both muscle and fat tissue were protruding from the fracture site in 14 cases. Fat tissue protrusion alone was found in 3 cases. In contrast, no protrusion was seen in one case. The incarcerated type of fat prolapse was found in 40% of cases, while muscle tissue prolapse was found in 75% of patients. Marginal irregularity or swelling of muscle was observed in 11 patients. There was good correlation of ocular motor disturbance and MRI findings. Disturbance of eyeball movement was observed in all patients with either incarcerated fat tissue or marginal irregularity or swelling of muscle. In contrast, restriction of eyeball movement was rare in cases of no incarceration, even if the fracture was wide. Deformity or marginal irregularity of the ocular muscle demonstrated in MRI may suggest damage an adhesion to the muscle wall. When MRI reveals incarceration or severe pWhen MRI reveals incarceration or severe prolapse of fat tissue, or deformity and marginal irregularity of the ocular muscle, surgical intervention should be considered. (author)

147

MRI findings in 20 DAI and their clinical outcomes  

International Nuclear Information System (INIS)

Twenty diffuse axonal injury (DAI) patients were investigated with MRI and X-ray CT scan from the acute to chronic stage. These neuroimaging findings were compared with clinical features such as Glasgow coma scales (GCS) on admission, age and Glasgow outcome scales (GOS) at 6 months injury. GCS's of 17 patients were less than 7 and those the remaining 3 were more than 8. The prognosis was very poor in patients with GCS's less than 5. According to age of the patient, the younger showed favorite outcome, but the older presented the poor outcome. X-ray CT scan revealed subarachnoid hemorrhage in 9 of 20 patients, hemorrhagic lesion in the brain stem in 2 and brain contusion in 3, but no evident lesions in 5. MRI demonstrated diagnostic findings such as hemorrhagic lesions in the deep cerebrum and high intensity lesions extending from the subcortical white matter to the brain stem in all patients. T2-weighted MRI demonstrated high intensity lesions to vanish in 9 patients within a few months. On the other hand, the patients who had evident lesion in the deep cerebrum on follow-up X-ray CT scan is very effective for evaluating acute head trauma, however, MRI is recommended not only for documenting DAI but also for predicting the neuropsychological prognosis. (author)

148

MRI findings in 20 DAI and their clinical outcomes  

Energy Technology Data Exchange (ETDEWEB)

Twenty diffuse axonal injury (DAI) patients were investigated with MRI and X-ray CT scan from the acute to chronic stage. These neuroimaging findings were compared with clinical features such as Glasgow coma scales (GCS) on admission, age and Glasgow outcome scales (GOS) at 6 months injury. GCS's of 17 patients were less than 7 and those the remaining 3 were more than 8. The prognosis was very poor in patients with GCS's less than 5. According to age of the patient, the younger showed favorite outcome, but the older presented the poor outcome. X-ray CT scan revealed subarachnoid hemorrhage in 9 of 20 patients, hemorrhagic lesion in the brain stem in 2 and brain contusion in 3, but no evident lesions in 5. MRI demonstrated diagnostic findings such as hemorrhagic lesions in the deep cerebrum and high intensity lesions extending from the subcortical white matter to the brain stem in all patients. T[sub 2]-weighted MRI demonstrated high intensity lesions to vanish in 9 patients within a few months. On the other hand, the patients who had evident lesion in the deep cerebrum on follow-up X-ray CT scan is very effective for evaluating acute head trauma, however, MRI is recommended not only for documenting DAI but also for predicting the neuropsychological prognosis. (author).

Okada, Yoshikazu; Shima, Takeshi; Nishida, Masahiro; Yamane, Kanji; Okita, Shinji; Naoe, Yasutaka; Yoshida, Akira; Hanaguri, Katsurou (Chugoku Rousai Hospital, Kure, Hiroshima (Japan))

1993-09-01

149

MRI findings of Wernicke encephalopathy revisited due to hunger strike  

Energy Technology Data Exchange (ETDEWEB)

Background and Purpose: The purpose of this study was to determine the characteristic magnetic resonance imaging (MRI) findings among a group of patients who presented with Wernicke encephalopathy (WE) due to the neurological complications of a long-term hunger strike (HS). Methods: MRI studies also including the fluid-attenuated inversion recovery (FLAIR) sequence and diffusion-weighted imaging (DWI) of six male patients with WE aged from 25 to 38 years (mean age 31 years) were evaluated. Results: In all subjects, T2-weighted sequences, FLAIR and DWI revealed a signal hyperintensity within the posteromedial thalami and surrounding the third ventricle. In particular, on coronal images, the hyperintense areas around the third ventricle showed a suggestive 'double wing' configuration. We observed an increased signal on proton-density and T2-weighted images in the mamillary bodies of three patients. Four patients demonstrated additional hyperintensities within the periaqueductal region and/or the tectal plate. At least one lesion area in five of six patients demonstrated contrast enhancement. Conclusion: The consistent imaging findings of our study suggest that MRI is a reliable means of diagnosing WE. Acute WE is sometimes underdiagnosed, yet early diagnosis and treatment of WE is crucial in order to avoid persistent brain damage. MRI, including postcontrast T1-weighted imaging, DWI beneath standardized T2-weighted imaging, and FLAIR sequences may prove to be a valuable adjunct to clinical diagnosis and to provide additional information in acute and/or subacute WE.

Unlu, Ercument [Department of Radiology, Trakya University School of Medicine, Mimar Sinan m, Muammer Aksoy c, Yorulmaz apt, No 50, D-1 22030 Edirne (Turkey)]. E-mail: drercument@yahoo.com; Cakir, Bilge [Department of Radiology, Trakya University School of Medicine, Mimar Sinan m, Muammer Aksoy c, Yorulmaz apt, No 50, D-1 22030 Edirne (Turkey); Asil, Talip [Department of Neurology, Trakya University School of Medicine, Edirne (Turkey)

2006-01-15

150

MRI findings of recurrent herpes simplex encephalitis in an infant  

International Nuclear Information System (INIS)

We report the MRI findings of a 2-year-old boy with recurrent herpes simplex encephalitis (HSE). At the age of 14 months, the patient developed a high fever that lasted over 1 week and he did not receive appropriate treatment. At 6 months after the fever, MRI showed marked atrophic changes in both deep temporal lobes with hyperintensity in the hippocampi and parahippocampal gyri. Thirteen months after the first episode of the fever, the patient was diagnosed with recurrent HSE by polymerase chain reaction assay of the CSF; MRI at this time revealed diffuse cortical swelling. Hyperintensity on T2-weighted images was noted in the occipito-parietal cortex bilaterally, the left thalamus, the subcortical white matter and the splenium of the corpus callosum. Recurrence of HSE may be more common in infants than previously thought. It is important to consider the possibility of recurrent HSE and to understand that MRI findings in HSV1 encephalitis in infants and young children appear to differ from those observed in neonates, older children and adults. (orig.)

151

CT and MRI findings of primary hepatic carcinoid tumor  

International Nuclear Information System (INIS)

Objective: To investigate the imaging findings of primary hepatic carcinoid tumor with dynamic MRI and spiral CT. Methods: Eleven cases with pathologically confirmed primary hepatic carcinoid tumor were analyzed retrospectively. Four cases were examined with spiral CT, and 8 cases were examined with MRI. Results: Two of 11 cases had multiple tumors, presenting as two or more nodular lesions, while the remaining 9 cases had single tumor. Four cases showed well-defined low density on the plain scan of CT, with central irregular cystic areas. Lesions enhanced unevenly on arterial phase of CT, with no enhancement in the central part. The edge of lesions showed delayed reduced enhancement on portal vein phase. than the arterial phase, while non-enhanced lesions in the center areas. Eight cases were detected by MRI, seven On MRI, 7 of 8 lesions showed uneven low signal on T1WI and high signal with central low intensity on T2WI. On arterial phase of MRI, 7 cases had uneven enhancement at the peripheral part and irregular non-enhanced signal in center. Lesions showed delayed mild enhancement in the peripheral parts, with a relatively smaller non-enhanced central area. One case was cystic, with high signal included in the extensive low density on T1WI. The case appeared high signal on T2WI and had uneven enhancement at the edge on arterial phase, low signal on delayed phase. Conclusion: Primary hepatic carcinoid tumor exhibits some iry hepatic carcinoid tumor exhibits some imaging features on plain and dynamic contrast-enhanced MRI and spiral CT, which can be t he clue for the diagnosis. (authors)

152

Spirometer-controlled cine magnetic resonance imaging to diagnose tracheobronchomalacia in pediatric patients  

DEFF Research Database (Denmark)

Tracheobronchomalacia (TBM) is defined as an excessive collapse of the intrathoracic trachea. Bronchoscopy is the gold standard to diagnose TBM, but bronchoscopy has major disadvantages, such as general anaesthesia. Cine-CT is a non-invasive alternative to diagnose TBM, but its use in children is restricted by ionizing radiation. Our aim was to evaluate the feasibility of spirometer-controlled cine-MRI as alternative to cine-CT in a retrospective study.12 children (mean 12 years, range 7-17), suspected to have TBM, underwent cine-MRI. Static scans were acquired at end-inspiration and expiration covering the thorax using a 3D SPGR sequence. 3D-Dynamic-scans were performed covering only the central airways. TBM was defined as a decrease of the trachea or bronchi diameter greater than 50% at end-expiration in the static and dynamic scans.The success rate of the cine-MRI protocol was 92%. Cine-MRI was compared with bronchoscopy or chest-CT in 7 subjects. TBM was diagnosed by cine-MRI in 7 out of 12 children (58%)and was confirmed by bronchoscopy or CT. In 4 patients, cine-MRI demonstrated tracheal narrowing that was not present in the static scans.Spirometer-controlled cine-MRI is a promising technique to assess TBM in children and has the potential to replace bronchoscopy.

Ciet, Pierluigi; Wielopolski, Piotr

2014-01-01

153

Spirometer-controlled cine magnetic resonance imaging used to diagnose tracheobronchomalacia in paediatric patients.  

Science.gov (United States)

Tracheobronchomalacia (TBM) is defined as an excessive collapse of the intrathoracic trachea. Bronchoscopy is the gold standard for diagnosing TBM; however it has major disadvantages, such as general anaesthesia. Cine computed tomography (CT) is a noninvasive alternative used to diagnose TBM, but its use in children is restricted by ionising radiation. Our aim was to evaluate the feasibility of spirometer-controlled cine magnetic resonance imaging (MRI) as an alternative to cine-CT in a retrospective study. 12 children with a mean age (range) of 12 years (7-17 years), suspected of having TBM, underwent cine-MRI. Static scans were acquired at end-inspiration and expiration covering the thorax using a three-dimensional spoiled gradient echo sequence. Three-dimensional dynamic scans were performed covering only the central airways. TBM was defined as a decrease of the trachea or bronchi diameter >50% at end-expiration in the static and dynamic scans. The success rate of the cine-MRI protocol was 92%. Cine-MRI was compared with bronchoscopy or chest CT in seven subjects. TBM was diagnosed by cine-MRI in seven (58%) out of 12 children and was confirmed by bronchoscopy or CT. In four patients, cine-MRI demonstrated tracheal narrowing that was not present in the static scans. Spirometer controlled cine-MRI is a promising technique to assess TBM in children and has the potential to replace bronchoscopy. PMID:23598953

Ciet, Pierluigi; Wielopolski, Piotr; Manniesing, Rashindra; Lever, Sandra; de Bruijne, Marleen; Morana, Giovanni; Muzzio, Pier Carlo; Lequin, Maarten H; Tiddens, Harm A W M

2014-01-01

154

Long-Term MRI Findings in Operated Rotator Cuff Tear  

International Nuclear Information System (INIS)

Purpose: To describe magnetic resonance imaging (MRI) findings at long-term follow-up after rotator cuff (RC) tear using standard MRI sequences without fat saturation. Material and Methods: Twenty-eight patients aged 55.8±7.6 underwent MRI examination 4.6±2.1 years after surgery for RC tear. Standard sequences in oblique coronal, oblique sagittal, and axial planes were obtained. The RC, including re-tears and tendon degeneration, was independently evaluated by two observers. Thickness of the supraspinatus tendon and narrowing of the subacromial space were measured. The clinical outcome was evaluated with the Constant score and compared with the MRI findings. Results: The RC tear was traumatic in 18 (64%) patients and degenerative in 10 (36%). At follow-up, 11 (39%) had normal RC tendons with good clinical outcome. Four (14%) patients had painful tendinosis without RC tear. A full-thickness RC tear was found in 7 (25%) patients and a partial tear in 6 (21%). In one patient with a full-thickness tear, and in two with partial tear, tendinosis was found in another of the RC tendons. The subacromial space was narrowed in 13 (46%) of the patients. A narrowing of the subacromial space correlated with re-tear (P<0.05). Conclusions: The RC may be evaluated with standard MRI sequences without fat saturation at long-term follow-up. A normal appearance of the RC is correlated with good clinical outcome, while re-tear and tendinosis are associated with painsociated with pain

155

Long-Term MRI Findings in Operated Rotator Cuff Tear  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To describe magnetic resonance imaging (MRI) findings at long-term follow-up after rotator cuff (RC) tear using standard MRI sequences without fat saturation. Material and Methods: Twenty-eight patients aged 55.8{+-}7.6 underwent MRI examination 4.6{+-}2.1 years after surgery for RC tear. Standard sequences in oblique coronal, oblique sagittal, and axial planes were obtained. The RC, including re-tears and tendon degeneration, was independently evaluated by two observers. Thickness of the supraspinatus tendon and narrowing of the subacromial space were measured. The clinical outcome was evaluated with the Constant score and compared with the MRI findings. Results: The RC tear was traumatic in 18 (64%) patients and degenerative in 10 (36%). At follow-up, 11 (39%) had normal RC tendons with good clinical outcome. Four (14%) patients had painful tendinosis without RC tear. A full-thickness RC tear was found in 7 (25%) patients and a partial tear in 6 (21%). In one patient with a full-thickness tear, and in two with partial tear, tendinosis was found in another of the RC tendons. The subacromial space was narrowed in 13 (46%) of the patients. A narrowing of the subacromial space correlated with re-tear (P<0.05). Conclusions: The RC may be evaluated with standard MRI sequences without fat saturation at long-term follow-up. A normal appearance of the RC is correlated with good clinical outcome, while re-tear and tendinosis are associated with pain.

Kyroelae, K.; Niemitukia, L.; Jaroma, H.; Vaeaetaeinen, U. [Kuopio Univ. Hospital (Finland). Dept. of Orthopaedics and Traumatology

2004-08-01

156

Brainstem evoked potentials in infantile spasms; Comparison with MRI findings  

Energy Technology Data Exchange (ETDEWEB)

In ten patients with infantile spasms, brainstem evoked potentials and MRI examinations were performed to evaluate the brainstem involvement. The result of short latency somatosensory evoked potentials (SSEP) following the right median nerve stimulation revealed abnormal findings including the absence or low amplitudes of the waves below wave P3 and delayed central conduction time in 7 of the ten patients. The result of auditory brainstem responses (ABR) revealed abnormal findings including low amplitudes of wave V, prolonged interpeak latency of waves I-V and absence of the waves below wave IV in 5 of the ten patients. The result of the MRI examinations revealed various degrees of the brainstem atrophy in 6 of the ten patients, all of whom showed abnormal brainstem evoked potentials. The result of this study demonstrates that patients with infantile spasms are frequently associated with brainstem dysfunction and raises the possibility that brainstem atrophy might be a cause of infantile spasms. (author).

Miyazaki, Masahito; Hashimoto, Toshiaki; Murakawa, Kazuyoshi; Tayama, Masanobu; Kuroda, Yasuhiro (Tokushima Univ. (Japan). School of Medicine)

1992-08-01

157

MRI findings of intraductal papillary neoplasm of intrahepatic bile ducts  

International Nuclear Information System (INIS)

Objective: To analyze the MR findings of intraductal papillary neoplasm of bile ducts (IPNB), and to improve the diagnostic accuracy. Methods: MRI findings of 19 cases of IPNB proven by histopathology were reviewed retrospectively. Results: Ten cases of intraductal papillary adenoma of the bile ducts and nine cases of intraductal papillary adenocareinoma were found at pathology. IPNB were intraductal tumors with numerous frondlike papillary projections. Some of them produced mucin that caused bitiary dilatation. Depending on the location of the tumor, dilatation of the entire biliary tree, disproportionate or aneurismal dilatation of the segmental or lobar bile ducts could occur. Nine cases showed aneurysmal dilation with multiple elongated or cordlike mass. Seven cases exhibited segmental bile duct dilation with filling defects. One case only showed dilatation of lobar bile ducts. Conclusion: MRI features of IPNB are helpful for distinguishing IPNB from other hepatic lesions. (authors)

158

MRI findings of tuberous sclerosis complex in pediatrics  

International Nuclear Information System (INIS)

Objective: To analyze MRI characteristic features of tuberous sclerosis. Methods: There are 14 patients were examined by MR routine scan and 3 patients with enhancement, all patients were proven by clinical examination. Results: Subependymal nodules, were detected in all cases, which were most commonly along the lateral wall of the lateral ventricles. Cortical tubers were detected in 10 cases, the patterns of cortical tubers were gyral core lesion and H-shaped lesion on MRI. The abnormal findings of white matter were radial linear ore wedge-shaped or irregular type on MR images. Subependymal giant cell astrocytomas were detected in 2 cases, renal angiomyolipoma was detected in 1 case. Conclusions: MRI is sensitive to find the changes in imaging diagnosis of TSC and is the first choice among the diagnostic imaging modalities. T1-weighted imaging (T1WI) and gradient echo sequences are more sensitive to the subependymal nodules than T2-weighted imaging (T2WI). T2WI and fluid-attenuated inversion recovery (FLAIR) are more sensitive to find the cortical tubers and abnormal white matter than T1WI. (authors)

159

Cardiac MRI. Diagnostic gain of an additional axial SSFP chest sequence for the detection of potentially significant extracardiac findings in the cardiac MRI examination setting  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Cardiac MRI (CMRI) is an effective method for imaging of the heart. The aim of our study was to assess whether an axial chest sequence in addition to the standard CMR examination setting has advantages in the detection of potentially significant extracardiac findings (PSEF). Materials and Methods: 400 consecutive patients were imaged at 1.5 T for clinical reasons. In addition to the standard long and short-axis views, an axial SSFP sequence was obtained covering the thorax from the lung apex to the diaphragm. All sequences were separately evaluated for PSEF. Results: A total of 25 PSEF were diagnosed in 400 patients, including 16 pleural effusions, a pulmonary fibrosis, a spondylodiscitis, ascites, lymphadenopathies, relapse of a mamma carcinoma, growth of adrenal glands metastases and diaphragmatic elevation. All 25 PSEF were detected by reading survey sequences. 24 of the 25 PSEF were detected by the additional SSFP chest sequence as well as the CINE sequences. Conclusion: In our study the additional axial SSFP chest sequence didn't show a benefit in the detection of PSEF. With the survey sequences we were able to detect all PSEF. We conclude that survey images should be assessed for additional findings. (orig.)

Roller, F.C.; Schneider, C.; Krombach, G.A. [University Hospital Giessen (Germany). Dept. Radiology; Schuhbaeck, A. [University Hospital Giessen (Germany). Dept. Cardiology; Rolf, A. [Kerckhoff Hospital Bad Nauheim (Germany). Dept. Cardiology

2014-01-15

160

MRI and neurological findings in patients with spinal metastases  

Energy Technology Data Exchange (ETDEWEB)

Background. Magnetic resonance imaging (MRI) is the recommended primary investigation method for metastatic spinal cord compression (MSCC). Initiating treatment before the development of motor deficits is essential to preserve neurological function. However, the relationship between MRI-assessed grades of spinal metastatic disease and neurological status has not been widely investigated. Purpose. To analyze the association between neurological function and MRI-based assessment of the extent of spinal metastases using two different grading systems. Material and Methods. A total of 284 patients admitted to our institution for initial radiotherapy or surgery for symptomatic spinal metastases were included in the study. Motor and sensory deficits were categorized according to the Frankel classification system. Pre-treatment MRI evaluations of the entire spine were scored for the extent of spinal metastases, presence and severity of spinal cord compression, and nerve root compression. Two MRI-based scales were used to evaluate the degree of cord compression and spinal canal narrowing and relate these findings to neurological function. Results. Of the patients included in the study, 28 were non-ambulatory, 49 were ambulatory with minor motor deficits, and 207 had normal motor function. Spinal cord compression was present in all patients with Frankel scores of B or C, 23 of 35 patients with a Frankel score of D (66%), and 48 of 152 patients with a Frankel score of E (32%). The percentage of patients with severe spinal canal narrowing increased with increasing Frankel grades. The grading according to the scales showed a significant association with the symptoms according to the Frankel scale (P < 0.001). Conclusion. In patients with neurological dysfunction, the presence and severity of impairment was associated with the epidural tumor burden. A significant number of patients had radiological spinal cord compression and normal motor function (occult MSCC)

Switlyk, M.D.; Hole, K.H.; Knutstad, K. [Department of Radiology and Nuclear Medicine, Oslo University Hospital, Norwegian Radium Hospital, Oslo (Norway)], E-mail: marta.switlyk@radiumhospitalet.no; Skjeldal, S.; Zaikova, O. [Department of Orthopedics, Oslo University Hospital, Norwegian Radium Hospital, Oslo (Norway); Hald, J.K. [Department of Radiology and Nuclear Medicine, Oslo University Hospital, Rikshospitalet, Oslo (Norway); Seierstad, T. [Department of Radiology and Nuclear Medicine, Oslo University Hospital, Norwegian Radium Hospital, Oslo (Norway); Faculty of Health Sciences, Buskerud University College, Drammen (Norway)

2012-12-15

161

Imaging Findings of Brain Death on 3-Tesla MRI  

Energy Technology Data Exchange (ETDEWEB)

To demonstrate the usefulness of 3-tesla (3T) magnetic resonance imaging (MRI) including T2-weighted imaging (T2WI), diffusion weighted imaging (DWI), time-of-flight (TOF) magnetic resonance angiography (MRA), T2*-weighted gradient recalled echo (GRE), and susceptibility weighted imaging (SWI) in diagnosing brain death. Magnetic resonance imaging findings for 10 patients with clinically verified brain death (group I) and seven patients with comatose or stuporous mentality who did not meet the clinical criteria of brain death (group II) were retrospectively reviewed. Tonsilar herniation and loss of intraarterial flow signal voids (LIFSV) on T2WI were highly sensitive and specific findings for the diagnosis of brain death (p < 0.001 and < 0.001, respectively). DWI, TOF-MRA, and GRE findings were statistically different between the two groups (p = 0.015, 0.029, and 0.003, respectively). However, cortical high signal intensities in T2WI and SWI findings were not statistically different between the two group (p = 0.412 and 1.0, respectively). T2-weighted imaging, DWI, and MRA using 3T MRI may be useful for diagnosing brain death. However, SWI findings are not specific due to high false positive findings.

Sohn, Chul Ho [Dept. of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul (Korea, Republic of); Lee, Hwa Pyung [Dept. of Occupational and Environmental Medicine, CHA Gumi Medical Center, CHA University, Gumi (Korea, Republic of); Park, Jun Beom [Dept. of Radiology, Korean Armed Force Daejeon Hospital, Daejeon (Korea, Republic of); Chang, Hyuk Won; Kim, Easlmaan; Park, Ui Jun; Kim, Hyoung Tae [Keimyung University College of Medicine, Dongsan Medical Center, Daegu (Korea, Republic of); Kim, Eun Hee [Dept. of Radiology, Seoul National University Bundang Hospital, Seongnam (Korea, Republic of); Ku, Jeong Hun [Dept. of Biomedical Engineering, Keimyung University College of Medicine, Daegu (Korea, Republic of)

2012-09-15

162

Imaging Findings of Brain Death on 3-Tesla MRI  

International Nuclear Information System (INIS)

To demonstrate the usefulness of 3-tesla (3T) magnetic resonance imaging (MRI) including T2-weighted imaging (T2WI), diffusion weighted imaging (DWI), time-of-flight (TOF) magnetic resonance angiography (MRA), T2*-weighted gradient recalled echo (GRE), and susceptibility weighted imaging (SWI) in diagnosing brain death. Magnetic resonance imaging findings for 10 patients with clinically verified brain death (group I) and seven patients with comatose or stuporous mentality who did not meet the clinical criteria of brain death (group II) were retrospectively reviewed. Tonsilar herniation and loss of intraarterial flow signal voids (LIFSV) on T2WI were highly sensitive and specific findings for the diagnosis of brain death (p < 0.001 and < 0.001, respectively). DWI, TOF-MRA, and GRE findings were statistically different between the two groups (p = 0.015, 0.029, and 0.003, respectively). However, cortical high signal intensities in T2WI and SWI findings were not statistically different between the two group (p = 0.412 and 1.0, respectively). T2-weighted imaging, DWI, and MRA using 3T MRI may be useful for diagnosing brain death. However, SWI findings are not specific due to high false positive findings.

163

Budd-Chiari syndrome: CT and MRI findings  

International Nuclear Information System (INIS)

Budd-Chiari syndrome is an uncommon but often fatal disorder resulting from obstruction of hepatic venous outflow tract at the level of the hepatic veins, the inferior vena cava. The CT and MRI characteristics of Budd-Chiari syndrome are reviewed in this article especially for displaying the exact site and extent of the obstruction. In addition to this direct sign, the indirect findings of venous obstruction such as the presence of intra-and extrahepatic collateral veins, caudate lobe enlargement, inhomogeneous liver enhancement, and regenerative nodules can also be demonstrated. Awareness of these findings is important for early diagnosis and appropriate treatment. (authors)

164

MRI findings in a case of canine tick born meningoencephalomyelitis.  

Science.gov (United States)

Tick borne encephalitis virus (TBE) is an endemic infectious agent in northeastern Switzerland causing mainly meningoencephalomyelitis in dogs. We report a canine case of tick born meningoencephalomyelitis resulting in flaccid tetraplegia and, subsequently, fatal respiratory failure. Magnetic resonance imaging (MRI) demonstrated intra-axial bilateral, symmetric, and hyperintense lesions in T2-weighted and Fluid Attenuated Inversion Recovery (FLAIR) sequences affecting thalamus, basal nuclei, cerebral white matter and ventral horns of the caudal cervical spine. These radiological findings overlap those described during flavivirus encephalitis affecting human beings. These lesions in MRI and diffusion weighted images correlated with areas of vasogenic edema detected histopathologically. In endemic regions, clinicians should be aware that bilateral, symmetrical hyperintense thalamic lesions in T2WI can be suggestive of flavivirus infection in dogs with encephalitis. PMID:25082637

Beckmann; Oevermann; Golini; Steffen; Kircher; Carrera

2014-08-01

165

A case of calcified intracranial tuberculoma presenting unique MRI findings  

International Nuclear Information System (INIS)

A 41-year-old male patient was admitted in our Ryukyu University Hospital complaining of parosmia. He had a history of miliary tuberculosis 21 years ago. Neurologically he showed left anosmia and hyperreflexia of the right upper extremity. Plain skull X-P and CT scan revealed a calcified mass, 25 mm in diameter, at the left frontal base. In MRI, the mass showed isointensity using the T1 weighted inversion recovery sequence and heterogenously low intensity using the T2 weighted spin echo sequence. Surgery was performed by bifrontal craniotomy. Then the tumor was removed totally including two coexisting small tumors. Histologically, they consisted of calcified caseous tissue and thick collagen capsule, suggesting old calcified tuberculomas. Postoperative course was uneventful and did not result in meningitis. Antituberculous therapy of streptmycin, isoniazid and rifapicin was given for 2 weeks, started on the operative day. MRI findings were presented in detail and the guideline of antituberculous therapy to the tuberculoma was discussed. (author)

166

MRI findings of cyclops lesions of the knee  

Scientific Electronic Library Online (English)

Full Text Available SciELO South Africa | Language: English Abstract in english Cyclops lesions develop in the anterior aspect of the intercondylar notch typically after anterior cruciate ligament (ACL) reconstruction or injury. It is a lesion consisting of fibrous tissue with or without cartilage and bony components. A cyclops lesion is one of the causes for reduced extension [...] and, in the cases reported here, also knee pain or discomfort after ACL reconstruction. We present the MRI features, particularly the features on proton density weighted turbo spin echo (PDW TSE) and proton density weighted turbo spin echo fat saturation (PDW TSE FS) sequences of four cases of cyclops lesions, and distinguish between the MRI findings of large and small lesions. We also describe a cyclops lesion after a posterior cruciate ligament reconstruction, not described in literature before.

C, Minné; MD, Velleman; FE, Suleman.

2012-04-01

167

MRI findings of Wernicke encephalopathy revisited due to hunger strike  

International Nuclear Information System (INIS)

Background and Purpose: The purpose of this study was to determine the characteristic magnetic resonance imaging (MRI) findings among a group of patients who presented with Wernicke encephalopathy (WE) due to the neurological complications of a long-term hunger strike (HS). Methods: MRI studies also including the fluid-attenuated inversion recovery (FLAIR) sequence and diffusion-weighted imaging (DWI) of six male patients with WE aged from 25 to 38 years (mean age 31 years) were evaluated. Results: In all subjects, T2-weighted sequences, FLAIR and DWI revealed a signal hyperintensity within the posteromedial thalami and surrounding the third ventricle. In particular, on coronal images, the hyperintense areas around the third ventricle showed a suggestive 'double wing' configuration. We observed an increased signal on proton-density and T2-weighted images in the mamillary bodies of three patients. Four patients demonstrated additional hyperintensities within the periaqueductal region and/or the tectal plate. At least one lesion area in five of six patients demonstrated contrast enhancement. Conclusion: The consistent imaging findings of our study suggest that MRI is a reliable means of diagnosing WE. Acute WE is sometimes underdiagnosed, yet early diagnosis and treatment of WE is crucial in order to avoid persistent brain damage. MRI, including postcontrast T1-weighted imaging, DWI beneath standardized T2-weighted imaging, and FLAIR sequences may prove to be a valuableFLAIR sequences may prove to be a valuable adjunct to clinical diagnosis and to provide additional information in acute and/or subacute WE

168

MRI findings of thoracolumbar spine fractures: a categorisation based on MRI examinations of 100 fractures  

International Nuclear Information System (INIS)

Objective. To define the state of different structures of the fractured thoracolumbar spine which may play a role in the immediate and long-term mechanical stability on MR images and to investigate the relationship of these findings with the AO classification of spinal injuries.Design. The state of the anterior longitudinal ligament, posterior longitudinal ligament, posterior ligamentous complex, cranial and caudal endplates, cranial and caudal discs and the vertebral body were defined using clinical, experimental and radiological data. The state of these structures was reported for each fracture on the MRI examinations and the different MRI features appropriate for different fracture classes were defined.Patients. MRI examinations of 70 patients with 100 fractures of the thoracolumbar spine were used for this study.Results. Wide variations were seen in the state of the structures studied. We could not find a definite pattern to relate these findings with the AO classification scheme.Conclusions. MR findings should be integrated into future classification schemes of thoracolumbar spine fractures. This would enable specific data about the structures involved in the stability of the spine to be acquired. Prospective studies using the criteria developed in this study may help resolve some of the controversies concerning the diagnosis and prognosis of these injuries as well as the development of new classification systems. (orig.)

169

Pelvic Hydatid Disease: CT and MRI Findings Causing Sciatica  

Energy Technology Data Exchange (ETDEWEB)

Pelvic masses, especially hydatid disease, rarely present with sciatica. We present the computed tomography (CT) and the magnetic resonance imaging (MRI) findings of a 49-year-old female patient with presacral hydatid disease, who was evaluated for her sciatica. We also want to emphasize the importance of assessing the pelvis of patients with symptoms and clinical findings that are inconsistent and that cannot be satisfactorily explained by the spinal imaging findings. isc herniation in the lumbar spine is a well-known etiology of back pains and sciatica, but whenever disc herniation of the lumbar spine is excluded by the employed imaging modalities, then the pelvis should be examined for other possible etiologies of nerve compression. We describe here a patient, who was complaining of sciatica, with no abnormal findings in her lumbar spinal magnetic resonance imaging (MRI). The cause of her sciatica was found to be associated with a pelvic hydatid cyst compressing the lumbosacral nerve plexus. In conclusion, if no pathology is evident for the lumbar discal structures, in connection with the cause of sciatica and lumbar back pains, then the pelvis should also be examined for the possible etiologies of compression of the lumbosacral nerve plexus. Whenever a multiseptated cyst is come across in a patient of an endemic origin with a positive history for hydatid disease like surgery, indicating recurrence, hydatid cyst is the most likely diagnosis.

Sanal, Hatice Tuba; Kocaoglu, Murat; Bulakbasi, Nail; Yildirim, Duzgun [Gulhane Military Medical School, Department of Radiology, 06018, Ankara (Turkmenistan)

2007-12-15

170

Incidental MRI Findings in Patients with Impaired Cognitive Function  

Energy Technology Data Exchange (ETDEWEB)

This study aims to evaluate the incidental findings on brain MRI of patients with cognitive function impairments. We analyzed magnetic resonance (MR) findings of 236 patients with decreased cognitive function. MR protocols include conventional T2 weighted axial images, fluid attenuated inversion recovery axial images, T1 weighted coronal 3-dimensional magnetization-prepared rapid acquisition of gradient echo and diffusion tensor images. We retrospectively evaluated the signal changes that suggest acute/subacute infarction and space occupying lesions which show mass effect. Incidental MR findings were seen in 16 patients. Nine patients (3.8%) showed increased signal intensity on trace map of diffusion tensor images suggesting acute/subacute infarctions. Space occupying lesions were detected in 7 patients, and 3 lesions (1.27%) had mass effect and edema and were considered clinically significant lesions that diminish cognitive functions. Several incidental MR findings were detected in patients with decreased cognitive function, and the incidence of aucte/subacute infarctions were higher. Proper evaluations of MRI in patients with impaired cognitive functions will be helpful in early detection and management of ischemic lesions and space occupying lesions.

Hwang, Yoon Joon [Dept. of Radiology, College of Medicine, Inje University, Ilsan Paik Hospital, Goyang (Korea, Republic of)

2013-01-15

171

MRI findings of spinal visceral larva migrans of Toxocara canis  

International Nuclear Information System (INIS)

Purpose: The purpose of this study is to investigate the MRI findings of visceral larva migrans (VLS) of Toxocara canis in spinal cord. Materials and methods: We retrospectively reviewed spinal MRI findings in eight patients with serologically proven Toxocara canis between 2005 and 2008. We evaluated the location, length, extent and migration of the lesion, MR signal intensity (SI), enhancement pattern, and swelling of the spinal cord. We evaluated clinical features including presenting symptoms and signs and treatment response. Results: Total 8 patients (M = 8; age range 36-79 years) were included. The lesions were located in the cervical or thoracic spinal cord in all patients. All lesions showed high SI and minimal or mild swelling of involved spinal cord on T2WI and focal nodular enhancement on posterior or posterolateral segment of spinal cord. The length of involved lesion was relatively short in most patients. There was a migration of lesion in one patient. In spite of albendazole or steroid treatment, neurological symptoms or signs were not significantly improved in all patients. Conclusion: Although all lesions show non-specific imaging findings like non-tumorous myelopathy mimicking transverse myelitis, single lesion, focal nodular enhancement on posterior or posterolateral segment of spinal cord, relatively short segmental involvement and migration of lesion may be characteristic findings of spinal VLM of Toxocara canis. In addition, the reluctant response anis. In addition, the reluctant response to the treatment may be characteristic of spinal VLM of Toxocara canis.

172

MRI findings of spinal visceral larva migrans of Toxocara canis  

Energy Technology Data Exchange (ETDEWEB)

Purpose: The purpose of this study is to investigate the MRI findings of visceral larva migrans (VLS) of Toxocara canis in spinal cord. Materials and methods: We retrospectively reviewed spinal MRI findings in eight patients with serologically proven Toxocara canis between 2005 and 2008. We evaluated the location, length, extent and migration of the lesion, MR signal intensity (SI), enhancement pattern, and swelling of the spinal cord. We evaluated clinical features including presenting symptoms and signs and treatment response. Results: Total 8 patients (M = 8; age range 36-79 years) were included. The lesions were located in the cervical or thoracic spinal cord in all patients. All lesions showed high SI and minimal or mild swelling of involved spinal cord on T2WI and focal nodular enhancement on posterior or posterolateral segment of spinal cord. The length of involved lesion was relatively short in most patients. There was a migration of lesion in one patient. In spite of albendazole or steroid treatment, neurological symptoms or signs were not significantly improved in all patients. Conclusion: Although all lesions show non-specific imaging findings like non-tumorous myelopathy mimicking transverse myelitis, single lesion, focal nodular enhancement on posterior or posterolateral segment of spinal cord, relatively short segmental involvement and migration of lesion may be characteristic findings of spinal VLM of Toxocara canis. In addition, the reluctant response to the treatment may be characteristic of spinal VLM of Toxocara canis.

Lee, In Ho, E-mail: leeinho1974@hanmail.ne [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Department of Radiology, Chungnam National University Hospital, 33 Munhwa-ro, Jung-gu, Daejeon 301-721 (Korea, Republic of); Kim, Sung Tae, E-mail: st7.kim@hotmail.co [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Oh, Dae Kun, E-mail: odk6464@nate.co [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Kim, Hyung-Jin, E-mail: hyungkim@skku.ed [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Kim, Keon Ha, E-mail: somatom@skku.ed [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Jeon, Pyoung, E-mail: drpjeon@gmail.co [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Byun, Hong Sik, E-mail: byun5474@skku.ed [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of)

2010-08-15

173

Incidental MRI Findings in Patients with Impaired Cognitive Function  

International Nuclear Information System (INIS)

This study aims to evaluate the incidental findings on brain MRI of patients with cognitive function impairments. We analyzed magnetic resonance (MR) findings of 236 patients with decreased cognitive function. MR protocols include conventional T2 weighted axial images, fluid attenuated inversion recovery axial images, T1 weighted coronal 3-dimensional magnetization-prepared rapid acquisition of gradient echo and diffusion tensor images. We retrospectively evaluated the signal changes that suggest acute/subacute infarction and space occupying lesions which show mass effect. Incidental MR findings were seen in 16 patients. Nine patients (3.8%) showed increased signal intensity on trace map of diffusion tensor images suggesting acute/subacute infarctions. Space occupying lesions were detected in 7 patients, and 3 lesions (1.27%) had mass effect and edema and were considered clinically significant lesions that diminish cognitive functions. Several incidental MR findings were detected in patients with decreased cognitive function, and the incidence of aucte/subacute infarctions were higher. Proper evaluations of MRI in patients with impaired cognitive functions will be helpful in early detection and management of ischemic lesions and space occupying lesions.

174

MRI findings of multiple focal nodular hyperplasia of the liver  

International Nuclear Information System (INIS)

Objective: To assess the diagnostic value of MRI on multiple focal nodular hyperplasia (FNH) of the liver. Methods: MR images of 9 cases with pathological-confirmed multiple FNH were retrospectively analyzed. MRI features of the lesions were correlated with pathological findings. Results: Multiple FNH was considered in all these 9 cases. Among them, the primary diagnosis was FNH in 5, hepatic adenoma in 3 and fibrolamellar hepatocellular carcinoma in 1 case. A total of 31 lesions were detected in the 9 cases. On T2WI, 19 lesions presented slightly high-signal intensity, and the other 12 presented iso-signal intensity. On T1WI, 12 lesions presented slightly low-signal intensity, 7 presented iso-signal intensity, and the other 12 presented high-signal intensity. On opposed-phase, the signal intensity of 1 lesion dropped unevenly. After bolus injection of contrast agent Gd-DTPA, in hepatic arterial phase 18 lesions showed mild to marked heterogeneous enhancement, 11 showed marked homogeneous enhancement, 1 showed moderate ring-like enhancement, and the last one did not have obvious enhancement. In portal venous and delayed phase, all the lesions turned to iso- or slightly high-signal intensity gradually. Sixteen of 31 lesions presented central scar, which demonstrated mild star-like enhancement in delayed phase. Conclusion: Multiple FNH presented certain MRI features, which contributed to the preoperative diagnosis. (authors)

175

MRI findings in childhood with neuronal ceroid lipofuscinosis  

International Nuclear Information System (INIS)

Objective: To characterize the MR imaging findings in different types of neuronal ceroid lipofuscinosis (NCL) in childhood. Methods: Six children with NCL and 6 age-matched control subjects were examined by using MRI. There was 2 patients with infantile NCL, 2 with late-infantile NCL, and 2 with juvenile NCL. Results: The cerebral atrophy was found in patients with infantile NCL, but the cerebellar atrophy was found in patients with late-infantile NCL and juvenile NCL; Hyperintensity in the centrum semiovale or periventricular white matter on T2WI was revealed in all cases; Decreased T2 signal was seen in the thalami in five patients, except for 1 juvenile NCL; Decreased T2 signal in the basal ganglia was seen in the 2 case with late-infantile NCL. No abnormal change was found in the control subjects. Conclusion: MRI is of great value in demonstrating the early changes of NCL. MRI especially facilitates the classification and early diagnosis of NCL

176

Far lateral lumbar disc extrusion: MRI findings and surgical treatment.  

Science.gov (United States)

This case report describes the magnetic resonance imaging (MRI) findings and the treatment of a far lateral extrusion of disc material at the sixth and seventh lumbar vertebrae (L6-L7) in a five-year-old male Alpine Dachsbracke dog referred to our hospital for investigation of the complaint of a one week progressive lameness in the left pelvic limb and poorly localized back pain. An extra-foraminal left lateral disc herniation impinging on the sixth lumbar nerve root was diagnosed by MRI examinations. Due to the far lateral position of the extruded disc material on MRI, surgical opening of the spinal canal was not necessary. Removal of the herniated soft disc material impinging on the L6 nerve root, and fenestration of the L6-L7 disc was performed laterally. To the author's knowledge 'far-lateral' disc herniation beyond the neuroforamen without any spinal canal contact has not been described in dogs until now. A complete recovery with no evidence of pain was achieved only after a couple of weeks after surgery. We acknowledge that it is possible that other pathological mechanisms may have contributed to clinical signs and to a delayed recovery. PMID:23857574

Fadda, A; Lang, J; Forterre, F

2013-01-01

177

MRI of cortical dysplasia - correlation with pathological findings  

International Nuclear Information System (INIS)

Cortical dysplasia (CD) is the most epileptogenic structural lesion associated with epilepsy and patients with intractable seizures caused by this condition are good surgical candidates. MRI plays an important role in detecting the abnormalities of CD. We clarified the MRI characteristics of CD by comparing imaging and histological findings in 20 patients with intractable seizures who underwent surgical resection. There were 12 males and eight females, mean age at operation was 15 years. MRI was performed at 1.5 tesla; T1-weighted, T2- and proton density-weighted spin-echo and fluid-attenuated inversion-recovery (FLAIR) images were obtained. The lesions were in the frontal lobe in nine cases, temporal in two, occipital in another two, insular in one and multilobar in six. Blurring of the grey/white matter junction was seen in all patients, and T2 prolongation in white matter and/or at the grey/white matter junction in 19. Abnormal signal intensity was more frequent in the white matter or at the grey/white matter junction than in the grey matter. FLAIR images made this abnormal high signal easier to appreciate, and we thought them very useful in this context. In areas of T2 prolongation, we saw dysplastic neurones and/or balloon cells, dysmyelination, and ectopic neuronal clustering histologically; glial proliferation played an important role in prolonging T2. (orig.)

178

Cine magnetic resonance imaging in congenital heart disease  

International Nuclear Information System (INIS)

Cine magnetic resonance imaging (MRI) was performed in 33 patients aged 19 days to 18 years (mean 5.1 years), who had congenital heart disease comfirmed at echocardiography or angiography. Prior to cine MRI, gated MRI with spin echo (SE) sequence was perfomed to evaluate cardiac structure. Cine MRI was demonstrated by fast low fip angle shot imaging technique with a 30 deg flip angle, 15 msec echo time, 30?40 msec pulse repetition time, and 128X128 acquisition matrix. Abnormalities of cardiac structure were extremely well defined in all patients. Intracardiac and intravasucular blood flow were visualized with high signal intensity area, whereas ventricular filling flow and left to right shunt flow through ventricular septal defect and atrial septal defect were visualized with low signal intensity area. However, in the patients who had severe congestive heart failure or respiratory arrhythmia, the good recording of cine MRI was not obtained because of artifacts. Gated MRI with SE sequence provides excellent visualization of fine structures, and cine MRI can provide high spatial resolution imaging of flow dynamic in a variety of congenital heart disease, noninvasively. (author)

179

MRI and pathological findings of epileptogenic lesions removed surgically  

International Nuclear Information System (INIS)

MRI revealed focal cerebral lesions in 19 patients, 12 males and 7 females, who had suffered from disabling seizures refractory to medical therapy for over one year; the lengths of the periods of therapy ranged from one to 17 years; mean: 8.8 years. Their ages at surgery ranged from 3 to 46 years; mean: 15.2 years. The results of other preoperative and intraoperative examinations, including mobile long-term ambulatory EEG monitoring, local CBF two-dimensional imaging by SPECT, and intraoperative cortical EEG, justified the surgical resection of those lesions revealed by MRI. These lesions were removed totally or subtotally. The pathological findings of the excised lesions were neuronal loss and gliosis in 10 cases (porencephaly, 2; arachnoid cyst, 3; post-traumatic scar, 1; nonspecific infarct, 4), hamartomatous pathology in 5 (hemartoma, 1; tuberous sclerosis, 4), and neoplasm in 4 (low-grade astrocytoma, 2; oligodendroglioma, 1; epidermoid, 1). The common pathological feature of these lesions was the proliferation of abnormal glial cells, which are sensitive to MRI imaging, especially to T2-weighted images. The postoperative follow-up terms of these 19 patients ranged from 6 to 23 months; mean: 15 months. Epileptic attacks had ceased in 12 of the 19 patients (63%), and there had been a marked improvement in both the frequency and severity of attacks in another 4. No permanent surgical complications or worsening of the seizures were seen in any patient. In the seizures were seen in any patient. In conclusion, MRI is sensitive to epileptogenic lesions in patients with medically intractable epilepsy and is helpful in defining their configurations and margins and in planning the surgical approach. (author)

180

MRI and pathological findings of epileptogenic lesions removed surgically  

Energy Technology Data Exchange (ETDEWEB)

MRI revealed focal cerebral lesions in 19 patients, 12 males and 7 females, who had suffered from disabling seizures refractory to medical therapy for over one year; the lengths of the periods of therapy ranged from one to 17 years; mean: 8.8 years. Their ages at surgery ranged from 3 to 46 years; mean: 15.2 years. The results of other preoperative and intraoperative examinations, including mobile long-term ambulatory EEG monitoring, local CBF two-dimensional imaging by SPECT, and intraoperative cortical EEG, justified the surgical resection of those lesions revealed by MRI. These lesions were removed totally or subtotally. The pathological findings of the excised lesions were neuronal loss and gliosis in 10 cases (porencephaly, 2; arachnoid cyst, 3; post-traumatic scar, 1; nonspecific infarct, 4), hamartomatous pathology in 5 (hemartoma, 1; tuberous sclerosis, 4), and neoplasm in 4 (low-grade astrocytoma, 2; oligodendroglioma, 1; epidermoid, 1). The common pathological feature of these lesions was the proliferation of abnormal glial cells, which are sensitive to MRI imaging, especially to T{sub 2}-weighted images. The postoperative follow-up terms of these 19 patients ranged from 6 to 23 months; mean: 15 months. Epileptic attacks had ceased in 12 of the 19 patients (63%), and there had been a marked improvement in both the frequency and severity of attacks in another 4. No permanent surgical complications or worsening of the seizures were seen in any patient. In conclusion, MRI is sensitive to epileptogenic lesions in patients with medically intractable epilepsy and is helpful in defining their configurations and margins and in planning the surgical approach. (author).

Moritake, Kouzo; Kikuchi, Haruhiko; Minamikawa, Jun (Kyoto Univ. (Japan). Faculty of Medicine) (and others)

1990-04-01

181

MRI findings of muscle involvement in idiopathic hypereosinophilic syndrome  

International Nuclear Information System (INIS)

A 40-year-old white man presented with fever, muscle pain, skin nodules and persistent hypereosinophilia over a period of 1 year. In addition, he had ventricular arrhythmias with episodes of tachycardia. Besides a lack of response to antiparasitic therapy, laboratory and pathological data excluded the diagnosis of trichinosis or any other parasitic infection. The patient's course of the disease over the previous 11/2 years was compatible with hypereosinophilic syndrome. In a muscle biopsy several eosinophilic perivascular and leucocytic intravascular infiltrates were found, indicative of muscle involvement by the disease. This is a report on the MRI findings of muscle involvement in idiopathic hypereosinophilic syndrome. (orig.)

182

Relationship between MRI and clinical findings in the acromioclavicular joint  

Energy Technology Data Exchange (ETDEWEB)

Objective: To determine the relationship between the magnetic resonance (MR) appearance of the acromioclavicular (AC) joint and the physical findings. Design: A total of 116 consecutive patients underwent routine MR imaging (MRI) of the shoulder over an 18-month period. All MR studies were interpreted by a blinded, experienced musculoskeletal radiologist. Eleven variables were studied: the presence of osteophytes; fluid in the joint; fluid outside the joint; high signal in the clavicle or in the acromion; fluid in the subacromial bursa; irregularity of the joint margins; bulging of the capsule; widening of the joint; the age of the patient; and the presence of a rotator cuff tear. The clinical information was supplied by an experienced shoulder surgeon blinded to the MRI findings. A control group of 23 normal volunteers was also studied. Results: The only statistically significant correlation (P=0.0249) was between high signal in the distal clavicle and degenerative changes found clinically. A weaker relationship existed between fluid in the joint and the clinical examination and between increasing degenerative changes and advancing age. Otherwise, no material relationship was found between any of the other MR abnormalities and the clinical picture. Conclusion: There appears to be no real correlation between the MR appearances and the clinical findings in the AC joint. (orig.)

Jordan, L.K.; Griffiths, H.L. [Department of Radiology, University of Missouri Health Care (United States); Kenter, K. [Department of Orthopedics, University of Missouri Health Care (United States)

2002-09-01

183

Digital cine-imaging  

International Nuclear Information System (INIS)

Digitization of fluoroscopic images has been developed for the digital cine imaging system as a result of the computer technology, television technology, and popularization of interventional radiology. Present digital cine imaging system is able to offer images similar to cine film because of the higher operatability and better image quality with the development of interventional radiology. As a result, its higher usefulness for catheter diagnosis examination except for interventional radiology was reported, and the possibility of having filmless cine is close to becoming a reality. However several problems have been pointed out, such as spatial resolution, time resolution, storage and exchangeability of data, disconsolidated viewing functions, etc. Anyhow, digital cine imaging system has some unresolved points and lots the needs to be discussed. The tendency of digitization is the passage of the time and we have to promote a study for more useful digital cine imaging system in team medical treatment which centers on the patients. (author)

184

Multidetector CT and MRI findings in periportal space pathologies  

International Nuclear Information System (INIS)

Periportal region is an anatomic space around portal vein comprising hepatic artery, bile duct, nerves, lymphatics and a potential space. Periportal pathologies may involve any of these structures diffusely or focally with characteristic radiologic findings. Radiologic findings can be helpful in differential diagnosis of pathologies of periportal structures including periportal cavernomatous transformation, hepatic artery aneurysm, biliary diseases, neurofibromatosis, lymphoma, langerhans' cell histiocytosis, periportal fatty infiltration and other causes of periportal halo in adult and pediatric patients. Lobar/segmental intrahepatic involvement can be seen in neurofibromatosis, cavernomatous transformation, fatty infiltration and periportal edema. In this review, we discuss CT and MRI findings of periportal pathologies which can be in the form of diffuse or segmental/lobar involvement

185

Eosinophilic Otitis Media: CT and MRI Findings and Literature Review  

International Nuclear Information System (INIS)

Eosinophilic otitis media (EOM) is a relatively rare, intractable, middle ear disease with extremely viscous mucoid effusion containing eosinophils. EOM is associated with adult bronchial asthma and nasal allergies. Conventional treatments for otitis media with effusion (OME) or for chronic otitis media (COM), like tympanoplasty or mastoidectomy, when performed for the treatment of EOM, can induce severe complications such as deafness. Therefore, it should be differentiated from the usual type of OME or COM. To our knowledge, the clinical and imaging findings of EOM of temporal bone are not well-known to radiologists. We report here the CT and MRI findings of two EOM cases and review the clinical and histopathologic findings of this recently described disease entity.

186

Cine magnetic resonance imaging for evaluation of cardiac structure and flow dynamics in congenital heart disease  

International Nuclear Information System (INIS)

Cine magnetic resonance imaging (Cine MRI) was performed in 20 patients aged 19 days to 13 years (mean 4.0 years), who had congenital heart disease confirmed at echocardiography or angiography. Prior to cine MRI, gated MRI was performed to evaluate for cardiac structure. Cine MRI was demonstrated by fast low fip angle shot imaging technique with a 30deg flip angle, 15 msec echo time, 30-40 msec pulse repetition time, and 128 x 128 acquisition matrix. Abnormalities of cardiac structure were extremely well defined in all patients by gated MRI. Intracardiac or intravascular blood flow were visualized in 17 (85%) of 20 patients by cine MRI. Left to right shunt flow through ventricular septal defect, atrial septal defect, and endocardial cushion defect were visualized with low signal intensity area. Low intensity jets flow through the site of re-coarctation of the aorta were also visualized. However, the good recording of cine MRI was not obtained because of artifacts in 3 of 20 patients (15%) who had severe congestive heart failure or respiratory arrhythmia. Gated MRI provides excellent visualization of fine structure, and cine MRI can provide high spatial resolution imaging of flow dynamic in a variety of congenital heart disease, noninvasively. (author)

187

Dobutamine cine magnetic resonance imaging after myocardial infarction  

International Nuclear Information System (INIS)

Dobutamine Cine MRI is a new diagnostic imaging technique in the pretreatment (revascularization) assessment of myocardial infarction patients. In this issue are reported the result of a comparative study of the diagnostic yield of dobutamine Cine MRI with that of stress echocardiography in the assessment of viable myocardium. A new method for analysis of Cine MR images, employing digital subtraction, aimed at decreasing subjectivity in the quantitative assessment of myocardial wall thickening. Twenty-six patients (21 men and 5 women) with a history of myocardial infarction who were scheduled for revascularization were submitted to stress echocardiography and dobutamine Cine MRI to evaluate contractile recovery of the segments considered akinetic or hypo kinetic at baseline echocardiography. Dobutamine was administered in growing doses (5, 10, 15?/kg/min). 16 segments of the left ventricle in each patient were considered. In the 416 segments studied, it was found that 307 normo kinetic, 64 scarred and 45 viable segments with stress echocardiography, versus 302 normo kinetic, 83 scarred and 31 viable segments with dobutamine MRI. Three months after revascularization 15 patients were examined to check contractile recovery of the segments considered as viable. Echocardiography had 79% sensitivity and 97% specificity, while Cine MRI had 96% and 86%, respectively. In patients with anteroseptal wall myocardial infarction stress echocardiography had 75% sensitivity and 97% cardiography had 75% sensitivity and 97% specificity. Echocardiography permits to distinguish viable myocardium and scarred myocardial tissue with good sensitivity and specificity, but Cine MRI performs better. Cine MRI has much higher sensitivity than stress echocardiography and thus makes the technique of choice to evaluate viable myocardium in these sites. The digital subtraction technique is as accurate as manual measurements, but reduces the error rate and permits quicker evaluation, particularly in subendocardial thickening

188

Chondromyxoid fibroma of the temporal bone: CT and MRI findings  

Energy Technology Data Exchange (ETDEWEB)

We present the case of a 44-year-old woman with chondromyxoid fibroma of temporal bone origin. Since this is the least common bone tumor of cartilaginous origin, it is highly unusual to find this tumor in the skull. In fact, the literature describes 18 cases of this form of neoplasia arising in the skull, only 4 of these having originated in the temporal bone. To date, the radiological features of these tumors, and especially features detected using the latest imaging modalities, have not been described in detail. This report is unique in that it is the first to present a case of chondromyxoid fibroma of the temporal bone accompanied by detailed CT and MRI findings. (orig.)

Tarhan, N.C.; Yologlu, Z.; Tutar, N.U.; Coskun, M.; Agildere, A.M. [Baskent Univ. School of Medicine, Bahcelievler Ankara (Turkey). Dept. of Radiology; Arikan, U. [Baskent Univ. School of Medicine, Bahcelievler Ankara (Turkey). Dept. of Pathology

2000-10-01

189

Chondromyxoid fibroma of the temporal bone: CT and MRI findings  

International Nuclear Information System (INIS)

We present the case of a 44-year-old woman with chondromyxoid fibroma of temporal bone origin. Since this is the least common bone tumor of cartilaginous origin, it is highly unusual to find this tumor in the skull. In fact, the literature describes 18 cases of this form of neoplasia arising in the skull, only 4 of these having originated in the temporal bone. To date, the radiological features of these tumors, and especially features detected using the latest imaging modalities, have not been described in detail. This report is unique in that it is the first to present a case of chondromyxoid fibroma of the temporal bone accompanied by detailed CT and MRI findings. (orig.)

190

Adult cerebellar medulloblastoma: CT and MRI findings in eight cases  

Directory of Open Access Journals (Sweden)

Full Text Available Medulloblastoma is a brain tumor of neuroepithelial origin, which represents 15 to 30% of all pediatric brain tumors, and less than 1% of CNS adult neoplasms. We report the imaging findings of 8 adult patients with medulloblastoma. The mean age was 35 years, ranging from 20 to 65 years, and the male:female rate was 3:5. The tumors were predominantly lateral (63%, hyperdense on CT scans (83%, and on the MRI, hypointense on T1 (100% and hyperintense on T2 (80% weighted images. It was seen intratumoral necrosis and cysts in six cases and calcifications in three. Hydrocephalus was observed in 5 cases and brain stem invasion in four. The imaging findings of medulloblastomas in adults are different of those in child, and also nonspecific. Although these tumors are uncommon in adults, they must be considered in the differential diagnosis of cerebellar masses in the posterior fossa of this age group.

Carvalho Neto Arnolfo de

2003-01-01

191

Characteristic CT and MRI findings of intracranial chondroma  

International Nuclear Information System (INIS)

Background. Intracranial chondromas are rare benign tumors. To date, few data are available on their neuroradiological features. Purpose. To describe a series of patients with intracranial chondroma and to analyze and discuss the computed tomography (CT) and magnetic resonance imaging (MRI) features that may distinguish chondromas from other intracranial neoplasms. Material and Methods. We retrospectively analyzed clinical and medical imaging data of six patients who had pathologically confirmed intracranial chondromas in our two institutions between July 2006 and September 2011. Both CT and MRI scanning were performed in all six cases. Results. Five tumors were located at the skull base and one originated from the falx. CT images revealed well-demarcated, irregular lobulated and variable density masses with obvious calci?cation (6/6), no or slight enhancement, without peritumoral edema, and frequently accompanied by erosion and destruction of surrounding bone (5/6). Tumor parenchyma appeared heterogeneously hypointense on T1WI, and hyperintense or mixed hyperintense and hypointense on T2WI, while the calcification appeared hypointense on T1WI and T2WI in five cases, demonstrating significant inhomogeneous enhancement on postcontrast MRI, which revealed the typical 'punica granatum seeds' sign. Only one case showed homogeneous low signal intensity on T1WI and high signal intensity on T2WI, and relatively uniform obvious enhancement on postcontrast scans. Conclusion. Tement on postcontrast scans. Conclusion. These characteristic CT and MR findings, combined with the location of the lesions and the history of a long duration of clinical symptoms, may prove helpful in differentiating intracranial chondromas from other more common tumors

192

Characteristic CT and MRI findings of intracranial chondroma  

Energy Technology Data Exchange (ETDEWEB)

Background. Intracranial chondromas are rare benign tumors. To date, few data are available on their neuroradiological features. Purpose. To describe a series of patients with intracranial chondroma and to analyze and discuss the computed tomography (CT) and magnetic resonance imaging (MRI) features that may distinguish chondromas from other intracranial neoplasms. Material and Methods. We retrospectively analyzed clinical and medical imaging data of six patients who had pathologically confirmed intracranial chondromas in our two institutions between July 2006 and September 2011. Both CT and MRI scanning were performed in all six cases. Results. Five tumors were located at the skull base and one originated from the falx. CT images revealed well-demarcated, irregular lobulated and variable density masses with obvious calci?cation (6/6), no or slight enhancement, without peritumoral edema, and frequently accompanied by erosion and destruction of surrounding bone (5/6). Tumor parenchyma appeared heterogeneously hypointense on T1WI, and hyperintense or mixed hyperintense and hypointense on T2WI, while the calcification appeared hypointense on T1WI and T2WI in five cases, demonstrating significant inhomogeneous enhancement on postcontrast MRI, which revealed the typical 'punica granatum seeds' sign. Only one case showed homogeneous low signal intensity on T1WI and high signal intensity on T2WI, and relatively uniform obvious enhancement on postcontrast scans. Conclusion. These characteristic CT and MR findings, combined with the location of the lesions and the history of a long duration of clinical symptoms, may prove helpful in differentiating intracranial chondromas from other more common tumors.

Duan, Fuhong; Qiu, Shijun; Liu, Zhenyin; Lv, Xiaofei; Feng, Xia; Xiong, Wei; An, Jie; Chen, Jing; Yang, Weicong; Wen, Chuhong [Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong (China)], E-mail: qiushijun006@163.com; Jiang, Jianwei; Chang, Jun [Department of Radiology, The Third Affiliated Hospital of Nantong University, Wuxi, Jiangsu (China)

2012-12-15

193

Assessing intra-fractional bladder motion using cine-MRI as initial methodology for Predictive Organ Localization (POLO) in radiotherapy for bladder cancer  

International Nuclear Information System (INIS)

Aim: To assess the feasibility of using cine-MR to study intra-fractional time-volume and volume-deformity patterns of the bladder during radiotherapy as initial methodology for Predictive Organ Localization (POLO). Methods: Nine patients receiving radiotherapy for localized muscle invasive bladder cancer were prospectively studied. Each had an MR scan performed on an empty bladder using a T1 weighted cine sequence over a period of 20 min. Scans were taken prior to, and repeated towards the end of, radiotherapy treatment. Time-volume sequences were determined and compared before and during radiotherapy. Absolute bladder volumes were then correlated with changes in bladder wall position. Results: The mean post void residual bladder volume prior to radiotherapy at time 0 was 113 cm3 [SD 53] and this did not differ significantly during radiotherapy -106 cm [SD 40] (p = 0.24, paired t-test analysis). A linear relationship was observed for the rate bladder filling over a 20 min period, which did not significantly change on the cine-MR during radiotherapy (regression coefficient 2.1 vs 1.6, respectively, p 0.51). Significant positive relationships were seen between volume and anterior (p = 0.02), superior (p 3. The 1.5 cm CTV-PTV margin was sufficient to account for expansion in the majority of cases with the only breac the majority of cases with the only breach occurring on the anterior wall in one patient. Conclusions: This study confirms the feasibility of using cine-MR for POLO. The development of such predictive methodology may compensate for the need to use an isotropic CTV-PTV margin to simply cover bladder filling when using image-guided radiotherapy

194

Cine-Club  

CERN Multimedia

  On the occasion of CERN’s 60th anniversary the CERN CineClub will be showing films from all CERN member states Thursday 10 April 2014 at 20:00 CERN Council Chamber   The Bothersome Man     Directed by Jens Lien (Norway, 2006) 95 minutes   Forty-year-old Andreas arrives in a strange city with no memory of how he got there. He is presented with a job, an apartment-even a beautiful girlfriend. But before long, Andreas notices that something is wrong. The people around him seem cut off from any real emotion, and communicate only in superficialities. All this seems to be governed by a shadowy group of technicians, the ominous Caretakers’, who make sure the city runs smoothly. When they find Andreas is not adjusting to his new life, they keep an increasing watch over his activities...”The Bothersome Man” is a fantastic fable, a parable for modern society’s consumerism and obsession with ap...

CineClub

2014-01-01

195

Case of calcified intracranial tuberculoma presenting unique MRI findings  

Energy Technology Data Exchange (ETDEWEB)

A 41-year-old male patient was admitted in our Ryukyu University Hospital complaining of parosmia. He had a history of miliary tuberculosis 21 years ago. Neurologically he showed left anosmia and hyperreflexia of the right upper extremity. Plain skull X-P and CT scan revealed a calcified mass, 25 mm in diameter, at the left frontal base. In MRI, the mass showed isointensity using the T/sub 1/ weighted inversion recovery sequence and heterogenously low intensity using the T/sub 2/ weighted spin echo sequence. Surgery was performed by bifrontal craniotomy. Then the tumor was removed totally including two coexisting small tumors. Histologically, they consisted of calcified caseous tissue and thick collagen capsule, suggesting old calcified tuberculomas. Postoperative course was uneventful and did not result in meningitis. Antituberculous therapy of streptmycin, isoniazid and rifapicin was given for 2 weeks, started on the operative day. MRI findings were presented in detail and the guideline of antituberculous therapy to the tuberculoma was discussed.

Kinjo, Toshihiko; Mukawa, Jiro; Miyagi, Kouichi; Takara, Eiichi; Mekaru, Susumu; Ishikawa, Yasunari

1988-05-01

196

Adhesive capsulitis: contrast-enhansed shoulder MRI findings  

International Nuclear Information System (INIS)

Full text: Evaluation of contrast-enhanced magnetic resonance imaging (CE-MRI) findings in cases clinically diagnosed as adhesive capsulitis (AC). CE-MRI images of 12 cases diagnosed as AC (13 shoulder joints) and nine control cases were retrospectively evaluated. AC diagnosis was establlished based on the history and clinical symptoms. MR signal intensity changes in the axillary pouch, rotator interval, biceps anchor and anterior posterior capsules were analysed with regard to the presence of abnormal soft tissue and contrast enhancement. Capsular and synovial thickening were measured in the axillary recess and rotator interval on coronal oblique CE T1-weighted images. Patient and control groups were compared by Fisher's exact and McNemar tests in terms of signal intensity changes and contrast enhancement in the described areas. Results: Comparison of the group with AC and the control group regarding intensity changes showed a statistically significant difference in the axillary pouch (P 0.05). Comparison of AC and control groups in terms of contrast enhancement revealed statistically significant differences in the axillary pouch, rotator interval, biceps anchor and anterior-posterior capsules (P < 0.001). A significant difference was determined between the AC and control groups with regard to thickening in axillary pouch and rotator interval (P < axillary pouch and rotator interval (P < 0.001). CE studies are useful for diagnosis of AC as it demonstrates thickening of specific soft-tissue areas like joint capsule and synovium.

197

MRI findings of olivopontocerebellar atrophy and Machado-Joseph disease  

International Nuclear Information System (INIS)

Olivopontocerebellar atrophy (OPCA) and Machado-Joseph disease (MJD) occasionally show similar clinical signs and symptoms, which makes differential diagnosis of OPCA and MJD difficult. In 1990, Savoiardo et al. reported that the transverse pontine fibers of OPCA patients had high signal intensity on T2-weighted MR images. To determine if the high signal intensity of the transverse pontine fibers is useful for the differential diagnosis of OPCA and MJD, we examined this abnormal intensity in patients diagnosed as OPCA or MJD. We observed the high intensity of transverse pontine fibers in all of the 18 OPCA patients. This finding, however, was not observed in any of the patients with the MJD. The high signal intensity of the transverse pontine fibers in T2-weighted images is characteristic of OPCA patients. Furthermore, the atrophy of pontine tegmentum is characteristic of patients with MJD. These findings correlate well with pathological findings of OPCA and MJD, indicating the usefulness of these MRI findings for the differential diagnosis of OPCA and MJD. (author)

198

MRI findings of muscle involvement in idiopathic hypereosinophilic syndrome  

Energy Technology Data Exchange (ETDEWEB)

A 40-year-old white man presented with fever, muscle pain, skin nodules and persistent hypereosinophilia over a period of 1 year. In addition, he had ventricular arrhythmias with episodes of tachycardia. Besides a lack of response to antiparasitic therapy, laboratory and pathological data excluded the diagnosis of trichinosis or any other parasitic infection. The patient`s course of the disease over the previous 1{sup 1}/{sub 2} years was compatible with hypereosinophilic syndrome. In a muscle biopsy several eosinophilic perivascular and leucocytic intravascular infiltrates were found, indicative of muscle involvement by the disease. This is a report on the MRI findings of muscle involvement in idiopathic hypereosinophilic syndrome. (orig.) With 3 figs., 25 refs.

Hundt, W.; Staebler, A.; Reiser, M. [Department of Diagnostic Radiology, Klinikum Grosshadern, Muenchen (Germany)

1999-04-01

199

SPIO-Enhanced MRI Findings of Well-Differentiated Hepatocellular Carcinomas: Correlation with MDCT Findings  

International Nuclear Information System (INIS)

This study was designed to assess superparamagnetic iron oxide (SPIO)-enhanced MRI findings of well-differentiated hepatocellular carcinomas (HCCs) correlated with their multidetector-row CT (MDCT) findings. Seventy-two patients with 84 pathologically proven well-differentiated HCCs underwent triple-phase MDCT and SPIO-enhanced MRI at a magnetic field strength of 1.5 Tesla (n = 49) and 3.0 Tesla (n = 23). Two radiologists in consensus retrospectively reviewed the CT and MR images for attenuation value and the signal intensity of each tumor. The proportion of hyperintense HCCs as depicted on SPIO-enhanced T2- or T2*-weighted images were compared in terms of tumor size ( 1 cm), five CT attenuation patterns based on arterial and equilibrium phases and magnetic field strength, by the use of univariate and multivariate analyses. Seventy-eight (93%) and 71 (85%) HCCs were identified by CT and on SPIO-enhanced T2- and T2*-weighted images, respectively. For the CT attenuation pattern, one (14%) of seven isodense-isodense, four (67%) of six hypodense- hypodense, four (80%) of five isodense-hypodense, 14 (88%) of 16 hyperdense- isodense and 48 (96%) of 50 hyperdense-hypodense HCCs were hyperintense (Cochran-Armitage test for trend, p 0.05). Most well-differentiated HCCs show hyperintensity on SPIOenhanced MRI, although the lesions show various CT attenuation patterns. The CT attenuation pattern is the main factor that affects the proportion of hyperintense well-differentiated HCCs as depicted on SPIO-enhanced MRI

200

MRI findings of multiple sclerosis involving the brainstem  

International Nuclear Information System (INIS)

To describe MRI findings of multiple sclerosis involving the brainstem. Among 35 cases of clinically definite multiple sclerosis, the authors retrospectively analysed 20 in which the brainstem was involved. MR images were analysed with regard to involvement sites in the brainstem or other locations, signal intensity, multiplicity, shape, enhancement pattern, and contiguity of brainstem lesions with cisternal or ventricular CSF space. The brainstem was the only site of involvement in five cases (25%), while simultaneous involvement of the brainstem and other sites was observed in 15 cases (75%). No case involved only the midbrain or medulla oblongata, and simultaneous involvement of the midbrain, pons and medulla oblongata was noted in 12 cases (60%). The most frequently involved region of the brainstem was the medulla oblongata (n=13; 90%), followed by the pons (n=17; 85%) and the midbrain (n=16; 80%). Compared with normal white matter, brainstem lesions showed low signal intensity on T1 weighted images, and high signal intensity on T2 weighted, proton density weighted, and FLAIR images. In 17 cases (85%), multiple intensity was observed, and the shape of lesions varied: oval, round, elliptical, patchy, crescentic, confluent or amorphous were seen on axial MR images, and in 14 cases (82%), coronal or sagittal scanning showed that lesions were long and tubular. Contiguity between brainstem lesions and cisternal or ventricular CSF space was seen in all cases (100%) invoSF space was seen in all cases (100%) involving midbrain (16/16) and medulla oblongata (18/18) and in 15 of 17 (88%) involving the pons. Contrast enhancement was apparent in 7 of 12 cases (58%). In the brainstem, MRI demonstrated partial or total contiguity between lesions and cisternal or ventricular CSF space, and coronal or sagittal images showed that lesions were long and tubuler

201

Cine Club  

CERN Multimedia

Thursday 22 August 2013 at 20:00 CERN Council Chamber The Angels’ Share Directed by Ken Loach (UK, 2012) Original version English; french subtitles; 101 minute This bitter sweet comedy follows protagonist Robbie as he sneaks into the maternity hospital to visit his young girlfriend Leonie and hold his newborn son Luke for the first time. Overwhelmed by the moment, he swears that Luke will not have the same tragic life he has had. Escaping a prison sentence by the skin of his teeth, he's given one last chance...While serving a community service order, he meets Rhino, Albert and Mo who, like him, find it impossible to find work because of their criminal records. Little did Robbie imagine how turning to drink might change their lives - not cheap fortified wine, but the best malt whiskies in the world. Will it be 'slopping out' for the next twenty years, or a new future with 'Uisge Beatha' the 'Water of Life?' Only the angels know.... Th...

Ciné Club

2013-01-01

202

Primary lymphoma of the cervix: MRI findings with gadolinium.  

Science.gov (United States)

MRI evaluation of primary cervical lymphoma has not been reported. We report such a case of primary cervical lymphoma, a lesion well seen and well delineated from normal tissue by MRI. Although primary lymphoma of the cervix is a rare entity, the disease does exist and can be well demonstrated by MRI. We evaluated the MR appearance of this lesion with both nonenhanced and gadolinium-enhanced imaging. PMID:1766319

Dang, H T; Terk, M R; Colletti, P M; Schlaerth, J B; Curtin, J P

1991-01-01

203

CINE CLUB  

CERN Multimedia

Thursday 7 October 2010 at 20:30 Jeudi 7 Octobre 2010 à 20:30 CERN Main Auditorium Amphithéâtre Principal Mystic River   By/de : Clint Eastwood (USA, 2003) 132 min With/avec : Sean Penn, Tim Robbins, Kevin Bacon, Laurence Fishburne, Marcia Gay Harden, Laura Linney   During a summer in 1975, Dave Boyle and two friends, Jimmy and Sean, are playing on a sidewalk in Boston when Dave is abducted by two men and subjected to sexual abuse over a period of several days. Eventually escaping, but haunted into adulthood by his trauma, Dave becomes a primary suspect when Jimmy's daughter, Katie, is found murdered. Sean, assigned to investigate the crime, finds himself facing both demons from the past and demons in the present as the circumstances surrounding Katie's death are uncovered.   Original version english with english subtitles Version originale anglaise soutitrée en anglais * * * * * * * Thursday 14 October 2010 at 20:30 ...

CINE CLUB

2010-01-01

204

CINE CLUB  

CERN Document Server

Thursday 11 November 2010 at 20:30 / Jeudi 11 Novembre 2010 à 20:30 CERN Main Auditorium / Amphithéâtre Principal LE CHOCOLAT By/de : Lasse Hallström (UK/USA, 2000) 121 min With/avec: Lena Olin, Juliette Binoche, Johny Depp, Judi Dench, Alfred Molina, Peter Stormare, Leslie Caron, Carrie-Anne Moss   Vianne Rocher and her young daughter are drifters who are met with skepticism and resistance when they move to a conservative town in rural France and open a chocolate shop during Lent. As Vianne begins to work her magic and help those around her, the townspeople are soon won over by her exuberance and her delicious chocolates - except for the mayor, who is determined to shut her down. When a group of river drifters visit the town, Vianne teaches the townspeople something about acceptance, and finds love for herself along the way. Original version english / french with german subtitles Version originale anglaise / française soutitr&...

CINE CLUB

2010-01-01

205

Cine club  

CERN Multimedia

Thursday 23 October 2014 at 20:00 CERN Council Chamber The Shop on Main Street Directed by Jan Kadar, Elmar Klos Slovakia, 1965, 125 minutes   In 1942, in a small town in Czechoslovakia, the poor carpenter Tony Brtko is assigned "Aryanizator" of a small shop on the main street by his fascist brother-in-law. His greedy wife is seduced with the promise of fortune, but Tony finds that the store owned by the deaf and senile seventy eight year-old widow Rozalie Lautmann is bankrupted and the old lady is financially supported by the Jewish community that promises a salary to him to help her. Tony befriends Mrs Lautmann and helps her in the store and repairs her furniture, and lures his wife with his salary. When the Jews are expelled from the town by the fascists, Tony decides to help the old lady. Original version Slovak; English subtitles   Thursday 30 October 2014 at 20:00 CERN Council Chamber High Noon Directed by Fred Zinnemann USA, 1952, 85 minutes On the ...

Ciné club

2014-01-01

206

MRI reporting by radiographers: Findings of an accredited postgraduate programme  

Energy Technology Data Exchange (ETDEWEB)

Aim: To analyse the objective structured examination (OSE) results of the first three cohorts of radiographers (n = 39) who completed an accredited postgraduate certificate (PgC) programme in reporting of general magnetic resonance imaging (MRI) investigations and to compare the agreement rates with those demonstrated for a small group of consultant radiologists. Method: Forty MRI investigations were used in the OSE which included the following anatomical areas and abnormal appearances: knee; meniscal/ligament injuries, bone bruises, effusions and osteochondral defects; lumbar spine: intervertebral disc morphology, vertebral collapse, tumours (bone and soft tissue), spinal stenosis and/or nerve root involvement; internal auditory meati (IAM): acoustic neuroma. Incidental findings included maxillary polyp, arachnoid cyst, renal cyst, hydroureter, pleural effusion and metastases (adrenal, lung, perirenal and/or thoracic spine). Sensitivity, specificity and total percentage agreement rates were calculated for all radiographers (n = 39) using all reports (n = 1560). A small representative subgroup of reports (n = 27) was compared to the three consultant radiologists' reports which were produced when constructing the OSE. Kappa values were estimated to measure agreement in four groups: consultant radiologists only; radiographers and each of the consultant radiologists independently. Results: The sensitivity, specificity and agreement rates for the three cohorts (combined) of radiographers were 99.0%, 99.0% and 89.2%, respectively. For the majority (5/9) of anatomical areas and/or pathological categories no significant differences (p < 0.05) were found between the mean Kappa scores (K = 0.47-0.76) for different groups of observers, whether radiographers were included in the group analysis or not. Where differences were apparent, this was in cases (4/9) where the variation was either not greater than found between radiologists and/or of no clinical significance. These results suggest therefore that in an academic setting, these groups of radiographers have the ability to correctly identify normal investigations and are able to provide a report on the abnormal appearances to a high standard. Further work is required to confirm the clinical application of these findings.

Piper, Keith [Allied Heath Professions Department, Canterbury Christ Church University, North Holmes Road, Canterbury, Kent CT1 1QU (United Kingdom)], E-mail: keith.piper@canterbury.ac.uk; Buscall, Kaie [Allied Heath Professions Department, Canterbury Christ Church University, North Holmes Road, Canterbury, Kent CT1 1QU (United Kingdom); Thomas, Nigel [X-Ray Department, Trafford General Hospital, Manchester M41 5SL (United Kingdom)

2010-05-15

207

MRI and radiographic findings in Currarino`s triad  

Energy Technology Data Exchange (ETDEWEB)

Currarino`s triad is a rare complex of a congential sacral bony abnormality, anorectal malformation and a presacral mass. Intractable constipation since birth is the leading symptom of this triad, which follows an autosomal dominant mode of heredity. We report conventional radiographic and MR findings in one family consisting of a mother and her two daughters. In all three cases, radiography revealed an abnormality of the os sacrum, the so-called scimitar sacrum. MR examination, undertaken next in our institution, was applied with T1-, T2- and proton density weighted sequences in all three orientations before and after i.v. application of gadolinium diethylene-triamine-pentaacetic acid (Gd-DTPA). In two patients we were able to diagnose the complete form of the triad and in one patient an incomplete form. In any case of a radiographically diagnosed scimitar sacrum in combination with constipation. Currarino`s triad should be considered. MRI, as the method of choice, should be the next step to detect a presacral mass and any anomalies of the spinal canal. The importance of early recognition lies in the high morbidity and mortality rates resulting from this disorder. (orig.)

Pfluger, T. [Dept. of Radiology, Klinikum Innenstadt, Muenchen Univ. (Germany); Czekalla, R. [Dept. of Radiology, Klinikum Innenstadt, Muenchen Univ. (Germany); Koletzko, S. [Dept. of Pediatrics, Klinikum Innenstadt, Muenchen Univ. (Germany); Muensterer, O. [Dept. of Radiology, Klinikum Innenstadt, Muenchen Univ. (Germany); Willemsen, U.F. [Dept. of Radiology, Klinikum Innenstadt, Muenchen Univ. (Germany); Hahn, K. [Dept. of Radiology, Klinikum Innenstadt, Muenchen Univ. (Germany)

1996-08-01

208

CT and MRI findings of calcified spinal meningiomas: correlation with pathological findings  

Energy Technology Data Exchange (ETDEWEB)

This study was designed to present characteristic CT and MR findings of calcified spinal meningiomas that correlate with pathological findings and to assess the efficacy of CT for the detection of calcifications within a mass in comparison to MRI. Between 1998 and 2009, 10 out of 11 patients who had pathologically confirmed psammomatous meningiomas showed gross calcifications on CT images and were included in this study. On CT scans of the 10 patients, the distribution pattern, morphology and number of calcifications within masses were evaluated. MRI was performed in seven patients and signal intensities of masses were assessed. The pathological results analyzed semi-quantitatively were compared with the density or the size of calcifications within a mass as seen on a CT scan. Seven of 10 masses were located at the thoracic spine level. Eight masses had intradural locations. The other two masses had extradural locations. Four masses were completely calcified based on standard radiographs and CT. Symptoms duration, the size of the mass and size or number of calcifications within a mass had no correlation. The location, size, and distribution pattern of calcifications within masses were variable. On MR images, signal intensity of calcified tumor varied on all imaging sequences. All the masses enhanced after injection of intravenous contrast material. A calcified meningioma should be first suggested when extradural or intradural masses located in the spine contain calcifications regardless of the size or pattern as depicted on CT, especially in the presence of enhancement as seen on MR images. (orig.)

Lee, Ji Won; Kim, Hak Jin [Pusan National University Hospital, Department of Radiology, Busan (Korea); Pusan National University School of Medicine, Medical Research Institute, Busan (Korea); Lee, In Sook [Pusan National University Hospital, Department of Radiology, Busan (Korea); Pusan National University School of Medicine, Medical Research Institute, Busan (Korea); Pusan National University School of Medicine, Department of Radiology, Busan (Korea); Choi, Kyung-Un [Pusan National University School of Medicine, Medical Research Institute, Busan (Korea); Pusan National University Hospital, Department of Pathology, Busan (Korea); Lee, Young Hwan [Catholic University of Daegu School of Medicine, Department of Radiology, Daegu (Korea); Yi, Jae Hyuck [Kyungpook National University Hospital, Department of Radiology, Daegu (Korea); Song, Jong Woon [Inje University Pusan Paik Hospital, Department of Radiology, Busan (Korea); Suh, Kyung Jin [Dongguk University Gyungju Hospital, College of Medicine, Dongguk University, Department of Radiology, Gyungju (Korea)

2010-04-15

209

MRI findings in little leaguer's shoulder  

Energy Technology Data Exchange (ETDEWEB)

Little leaguer's shoulder, a stress injury of the proximal humeral physis, should be considered in the differential diagnosis for an adolescent baseball player with shoulder pain, especially if the player is pitching regularly in a competitive environment. While roentgenographs may or may not be helpful, depending on the duration and severity of the injury, we report the MRI appearance of a case of little leaguer's shoulder. We found MRI helpful in diagnosing injury to the growth plate that was radiographically occult; furthermore, we were able to document the patient's progress with a follow-up MRI examination, which showed improvement with treatment. (orig.)

Song, James C.; Lazarus, Martin L. [Northwestern University and Evanston Northwestern Healthcare, Department of Radiology, Evanston, IL (United States); Song, Alexandra Pae [Health Department, Evanston, IL (United States)

2006-02-15

210

Ethical and Practical Considerations in the Management of Incidental Findings in Pediatric MRI Studies  

Science.gov (United States)

Objective: The authors examined the ethical and practical management issues resulting from the detection of incidental abnormal findings on magnetic resonance imaging (MRI) research studies in healthy pediatric volunteers. Method: A retrospective examination of the findings from 60 clinical reports of research MRI scans from a cohort of healthy…

Kumra, Sanjiv; Ashtari, Manzar; Anderson, Britt; Cervellione, Kelly L.; Kan, Li

2006-01-01

211

Determining Microvascular Obstruction and Infarct Size with Steady-State Free Precession Imaging Cardiac MRI  

Science.gov (United States)

Purpose In cardiac MRI (cMRI) injection of contrast medium may be performed prior to the acquisition of cine steady-state free precession (SSFP) imaging to speed up the protocol and avoid delay before late Gadolinium enhancement (LGE) imaging. Aim of this study was to evaluate whether a condensed clinical protocol with contrast cine SSFP imaging is able to detect early microvascular obstruction (MO) and determine the infarct size compared to the findings of LGE inversion recovery sequences. Materials and Methods The study complies with the Declaration of Helsinki and was performed following approval by the ethic committee of the University of Erlangen-Nuremberg. Written informed consent was obtained from every patient. 68 consecutive patients (14 females/54 males) with acute ST-elevation myocardial infarction (STEMI) treated by percutaneous coronary revascularization were included in this study. CMRI was performed 6.6±2 days after symptom onset and MO and infarct size in early contrast SSFP cine imaging were compared to LGE imaging. Results MO was detected in 47/68 (69%) patients on cine SSFP and in 41/68 (60%) patients on LGE imaging. In 6 patients MO was found on cine SSFP imaging but was not detectable on LGE imaging. Infarct size on cine SSFP showed a strong agreement to LGE imaging (intraclass correlation coefficient [ICC] of 0.96 for enddiastolic, p<0.001 and 0.96 for endsystolic, p<0.001 respectively). Significant interobserver agreement was found measuring enddiastolic and endsystolic infarct size on cine SSFP imaging (p<0.01). Conclusions In patients after STEMI infarct size and presence of MO can be detected with contrast cine SSFP imaging. This could be an option in patients who are limited in their ability to comply with the demands of a cMRI protocol. PMID:25793609

Wuest, Wolfgang; Lell, Michael; May, Matthias; Scharf, Michael; Schlundt, Christian; Achenbach, Stephan; Uder, Michael; Schmid, Axel

2015-01-01

212

MRI spectrum of findings in lumbosacral epidural lipomatosis  

International Nuclear Information System (INIS)

Lumbosacral epidural lipomatosis (LEL) has been defined as a disease produced by excessive fat deposition within the spinal canal. In the pre MRI-era, this entity has been commonly overlooked. While a mild (or moderate) epidural fat hypertrophy is basically asymptomatic, severe LEL represents the symptomatic end-stage of this disease, conducing in many cases to surgical fat debulking. Since LEL may be concurrent with other substantial spinal abnormalities (e.g. disk herniation) MRI exams may increase our awareness of this condition to avoid its underestimation. MRI enables a reliable LEL characterization and may show its eventual reversibility in obese or corticosteroid receiving patients. This pictorial essay illustrates the usefulness of MRI to demonstrate the ongoing process of epidural fat accumulation in mild, moderate and severe LEL. The different morphologic patterns of the thecal sac produced by advanced LEL are analyzed. LEL and concurrent spinal disorders with superimposed neurological symptoms and signs are illustrated. (author)

213

Rupture of plantaris muscle - a mimic: MRI findings.  

Science.gov (United States)

Calf muscle trauma commonly involves the gastrocnemius and soleus muscles. Plantaris muscle is a vestigial muscle coursing through the calf. Similar clinical features may be seen with injury to the plantaris muscle. It can also mimic other conditions like deep vein thrombosis, rupture of Baker's cyst, and tumors. MRI is helpful in identifying and characterizing it. We report two cases of ruptured plantaris muscle seen on MRI. PMID:22616036

Gopinath, T N; Jagdish, J; Krishnakiran, K; Shaji, P C

2012-01-01

214

Teaching neuroimages: neonatal parechovirus encephalitis: typical MRI findings.  

Science.gov (United States)

A full-term 9-day-old girl presented with fever, irritability, and seizures. The routine CSF examination, cranial ultrasound, and laboratory tests were normal. Brain MRI showed diffuse white matter abnormality (figure). Human parechovirus (HPeV) type 3 was isolated in both CSF and blood. The neurodevelopmental outcome at 4 months is poor, and MRI shows an extensive cystic leukomalacia in the frontal white matter. PMID:24446179

Belcastro, Vincenzo; Bini, Paolo; Barachetti, Roberta; Barbarini, Mario

2014-01-21

215

Dobutamine cine magnetic resonance imaging after myocardial infarction; Cine Risonanza Magnetica con dobutamina dopo infarto del miocardio  

Energy Technology Data Exchange (ETDEWEB)

Dobutamine Cine MRI is a new diagnostic imaging technique in the pretreatment (revascularization) assessment of myocardial infarction patients. In this issue are reported the result of a comparative study of the diagnostic yield of dobutamine Cine MRI with that of stress echocardiography in the assessment of viable myocardium. A new method for analysis of Cine MR images, employing digital subtraction, aimed at decreasing subjectivity in the quantitative assessment of myocardial wall thickening. Twenty-six patients (21 men and 5 women) with a history of myocardial infarction who were scheduled for revascularization were submitted to stress echocardiography and dobutamine Cine MRI to evaluate contractile recovery of the segments considered akinetic or hypo kinetic at baseline echocardiography. Dobutamine was administered in growing doses (5, 10, 15{gamma}/kg/min). 16 segments of the left ventricle in each patient were considered. In the 416 segments studied, it was found that 307 normo kinetic, 64 scarred and 45 viable segments with stress echocardiography, versus 302 normo kinetic, 83 scarred and 31 viable segments with dobutamine MRI. Three months after revascularization 15 patients were examined to check contractile recovery of the segments considered as viable. Echocardiography had 79% sensitivity and 97% specificity, while Cine MRI had 96% and 86%, respectively. In patients with anteroseptal wall myocardial infarction stress echocardiography had 75% sensitivity and 97% specificity. Echocardiography permits to distinguish viable myocardium and scarred myocardial tissue with good sensitivity and specificity, but Cine MRI performs better. Cine MRI has much higher sensitivity than stress echocardiography and thus makes the technique of choice to evaluate viable myocardium in these sites. The digital subtraction technique is as accurate as manual measurements, but reduces the error rate and permits quicker evaluation, particularly in subendocardial thickening. [Italian] La cine Risonanza Magnetica (cine RM) con stimolo farmacologico {beta}-adrenergico (stress dobutamina) rappresenta una nuova indagine diagnostica nella valuazione pretrattamento di rivascolarizzazione del paziente con infarto del miocardio. Scopo dello studio e' quello di verificare la validita' diagnostica della cine RM con stimolo farmacologico in confronto con l'ecocardiografia con stimolo farmacologico nella valutazione della vitalita' del miocardio e di proporre un nuovo metodo d'analisi delle immagini di cine RM mediante la sottrazione elettronica d'immagine al fine di ridurre gli elementi soggettivi nella valutazione quantitativa dell'ispessimento parietale. Ventisei pazienti (21 maschi, 5 femmine) con pregresso infarto del miocardio in attesa di intervento di rivascolarizzazione sono stati sottoposti a ecocardiografia con stimolo farmacologico mediante dobutamina e a esame cine RM con dobutamina al fine di verificare la ripresa contrattile dei segmenti giudicati acinetici o ipocinetici all'esame ecocardiografico di base. E' stata infusa dobutamina a dosi crescenti (5, 10, 15{gamma}/kg/min). Per ogni paziente sono stati considerati 16 segmenti del ventricolo sinistro. Nel totale di 416 segmenti miocardici considerati l'analisi qualitativa del movimento parietale con ecocardiografia con dobutamina ha dimostrato 307 segmenti normocinetici, 64 cicatriziali e 45 vitali mentre con la cine Rm sono stati osservati rispettivamente 302 segmenti come normocinetici, 83 cicatriziali e 31 vitali. Tre mesi dopo l'intervento di rivascolarizzazione 15 pazienti sono stati rivalutati per verificare la ripresa contrattile dei segmenti giudicati vitali. L'esame ecocardiografico ha mostrato sensibilita' del 79% e specificita' del 97% mentre per l'analisi qualitativa mediante cine RM la sensibilita' e' stata del 96% e la specificita' dell'86%. Nei pazienti con infarto anterosettale l'ecocardiografia con dobutamina ha dimostrato sensibilita' e specificita' rispetti

Giovagnoni, A.; Ligabue, G.; Romagnoli, R. [Modena Univ., Modena (Italy). Scienze Radiologiche, Dipt. di Medicina Interna; Reggio Emilia Univ., Reggio Emilia (Italy). Cattedra di Cardiologia; Rossi, R.; Muia, N.; Modena, M.G. [Modena Univ., Modena (Italy). Dipt. di Scienze Mediche, Oncologiche e Radiologiche; Reggio Emilia Univ. (Italy). Dipt. di Scienze Mediche, Oncologiche e Radiologiche

1999-12-01

216

Neurotuberculosis: Hallazgos intracraneanos en RM Neurotuberculosis: Intracranial MRI findings  

Directory of Open Access Journals (Sweden)

Full Text Available Objetivos. Mostrar nuestra casuística de pacientes con diagnóstico de tuberculosis intracraneana y describir los diferentes tipos de lesiones documentadas en Resonancia Magnética (RM que caracterizan a esta entidad. Materiales y Métodos. Para el presente trabajo fueron seleccionados, de forma retrospectiva, 20 pacientes con hallazgos positivos de tuberculosis intracraneana. Doce eran de sexo masculino y 8 de sexo femenino, con un rango etario de 8 meses a 49 años de edad (edad media: 21 años. El diagnóstico clínico fue realizado con punción lumbar y cultivo de LCR. Once pacientes presentaron serología positiva para VIH. Las RM fueron realizadas en resonadores de 0.5T y 1.5T, complementadas en dos casos con Tomografía Computada (TC de cerebro. A dos pacientes se les realizó difusión (DWI y a un paciente espectroscopía. Resultados. Del total de pacientes (n=20, 14 presentaron compromiso subaracnoideo en la convexidad y 13 compromiso subaracnoideo cisternal basal (afectación leptomeníngea. En 13 se observaron tuberculomas y 11 presentaron angeítis de grandes vasos; mientras que 7 tuvieron angeítis de pequeños vasos, 7 hidrocefalia, 6 infartos parenquimatosos y 1 afectación paquimeníngea. Quince pacientes tenían lesiones combinadas. Conclusión. La localización más frecuente de neurotuberculosis en esta serie fue meníngea con compromiso leptomeníngeo (14 pacientes con afectación subaracnoidea, seguido de afectación cisternal en 13 pacientes y sólo en un caso fue paquimeníngea. La manifestación parenquimatosa más frecuente fue el tuberculoma (granulomas tuberculosos con 13 casos. De estos, 5 presentaron un patrón miliar y sólo uno comportamiento pseudotumoral.Purposes. To report our case series of patients with a diagnosis of intracranial tuberculosis and to describe the different types of lesions characterizing this entity on Magnetic Resonance Imaging (MRI. Materials and Methods. For the present study, we retrospectively selected 20 patients with positive MRI findings of intracranial tuberculosis. Twelve of them were males and 8 were females, with an age range of between 8 months and 49 years (mean age: 21years. Clinical diagnosis was obtained by lumbar puncture and cerebrospinal fluid (CSF culture. Eleven patients presented positive HIV serology. MRIs were performed using 0.5T and 1.5 T scanners and computed tomography (CT of the brain was also performed in two patients. Diffusion-weighted technique was performed in two patients and spectroscopy in one patient. Results. Of the total patients studied (n=20, 14 presented convexity subarachnoid involvement and 13 subarachnoid basal cystern involvement (leptomeningeal involvement, 13 presented tuberculomas, 11 large-vessel angiitis, 7 smallvessel angiitis, 7 hydrocephalia, 6 parenchymatous infarction and one pachymeningeal involvement. Combined lesions were observed in 15 patients. Conclusion. The most frequent location of neurotuberculosis in this series was meningeal with leptomeningeal involvement (14 patients with subarachnoid involvement, followed by cysternal involvement in 13 patients, and only one patient had pachymeningeal involvement. The most frequent parenchymatous finding of tuberculosis was tuberculoma in 13 patients, 5 with a miliary pattern and only one with pseudo-tumoral behavior.

Jorge Docampo

2012-06-01

217

Neurotuberculosis: Hallazgos intracraneanos en RM / Neurotuberculosis: Intracranial MRI findings  

Scientific Electronic Library Online (English)

Full Text Available Objetivos. Mostrar nuestra casuística de pacientes con diagnóstico de tuberculosis intracraneana y describir los diferentes tipos de lesiones documentadas en Resonancia Magnética (RM) que caracterizan a esta entidad. Materiales y Métodos. Para el presente trabajo fueron seleccionados, de forma retro [...] spectiva, 20 pacientes con hallazgos positivos de tuberculosis intracraneana. Doce eran de sexo masculino y 8 de sexo femenino, con un rango etario de 8 meses a 49 años de edad (edad media: 21 años). El diagnóstico clínico fue realizado con punción lumbar y cultivo de LCR. Once pacientes presentaron serología positiva para VIH. Las RM fueron realizadas en resonadores de 0.5T y 1.5T, complementadas en dos casos con Tomografía Computada (TC) de cerebro. A dos pacientes se les realizó difusión (DWI) y a un paciente espectroscopía. Resultados. Del total de pacientes (n=20), 14 presentaron compromiso subaracnoideo en la convexidad y 13 compromiso subaracnoideo cisternal basal (afectación leptomeníngea). En 13 se observaron tuberculomas y 11 presentaron angeítis de grandes vasos; mientras que 7 tuvieron angeítis de pequeños vasos, 7 hidrocefalia, 6 infartos parenquimatosos y 1 afectación paquimeníngea. Quince pacientes tenían lesiones combinadas. Conclusión. La localización más frecuente de neurotuberculosis en esta serie fue meníngea con compromiso leptomeníngeo (14 pacientes con afectación subaracnoidea, seguido de afectación cisternal en 13 pacientes) y sólo en un caso fue paquimeníngea. La manifestación parenquimatosa más frecuente fue el tuberculoma (granulomas tuberculosos) con 13 casos. De estos, 5 presentaron un patrón miliar y sólo uno comportamiento pseudotumoral. Abstract in english Purposes. To report our case series of patients with a diagnosis of intracranial tuberculosis and to describe the different types of lesions characterizing this entity on Magnetic Resonance Imaging (MRI). Materials and Methods. For the present study, we retrospectively selected 20 patients with posi [...] tive MRI findings of intracranial tuberculosis. Twelve of them were males and 8 were females, with an age range of between 8 months and 49 years (mean age: 21years). Clinical diagnosis was obtained by lumbar puncture and cerebrospinal fluid (CSF) culture. Eleven patients presented positive HIV serology. MRIs were performed using 0.5T and 1.5 T scanners and computed tomography (CT) of the brain was also performed in two patients. Diffusion-weighted technique was performed in two patients and spectroscopy in one patient. Results. Of the total patients studied (n=20), 14 presented convexity subarachnoid involvement and 13 subarachnoid basal cystern involvement (leptomeningeal involvement), 13 presented tuberculomas, 11 large-vessel angiitis, 7 smallvessel angiitis, 7 hydrocephalia, 6 parenchymatous infarction and one pachymeningeal involvement. Combined lesions were observed in 15 patients. Conclusion. The most frequent location of neurotuberculosis in this series was meningeal with leptomeningeal involvement (14 patients with subarachnoid involvement, followed by cysternal involvement in 13 patients), and only one patient had pachymeningeal involvement. The most frequent parenchymatous finding of tuberculosis was tuberculoma in 13 patients, 5 with a miliary pattern and only one with pseudo-tumoral behavior.

Jorge, Docampo; Carolina, Mariluis; Nadia, González; Carlos, Morales; Claudio, Bruno.

2012-06-01

218

MRI findings of vascular dementia following hypertensive intracerebral hemorrhage  

International Nuclear Information System (INIS)

This study reviewed 23 patients with vascular dementia following hypertensive intracerebral hemorrhage. There were 12 male and 11 female patients with an age range between 46 and 88 years (median, 62.6 years). They consisted of 9 putaminal, 9 thalamic and 5 recurrent hemorrhages. Vascular dementia was diagnosed by Hasegawa's test for the demented patient. Patients with Hasegawa's score of less than 21.5 were enrolled as dementia. A superconducting magnet MIR system (MRT-50A, 0.5 Tesla) was used. The highest incidence of finding depicted by MRI was cortical atrophy (100%), followed by periventricular high intensity zone (91.3%), periventricular of deep white matter patchy-like high intensity area (73.9%), hydrocephalus and multiple putaminal low intensity spots (52.1%), scattered cortical high intensity area (47.8%) and subdural ring-like high intensity zone (21.7%). Older group of more than 71 years had more frequent multiple putaminal low intensity spots, scattered cortical high intensity area, and relatively frequent hydrocephalus, periventricular high intensity zone, as compared with younger group of less than 69 years. Subdural ring-like high intensity zone was frequently observed in patients with an interval from onset of more than 2 years. Multiple putaminal low intensity spots were frequently seen in patients with less than 1 year's interval. Multiple putaminal low intensity spots and periventricular high intensity zone were more frequently observed in patients were more frequently observed in patients with thalamic and recurrent hemorrhages, periventricular or deep white matter patchy-like high intensity areas were seen more frequently in patients with putaminal hemorrhage. Both scattered cortical high intensity area and subdural ring-like high intensity zone were more frequently observed in patients with recurrent hemorrhages. Both hydrocephalus and multiple putaminal low intensity spots were more common in demented patients than predemented patients. (J.P.N.)

219

Evaluation of atrial, ventricular and atrioventricular septal defects by cine magnetic resonance imaging  

International Nuclear Information System (INIS)

Cine magnetic resonance imaging (MRI) was performed on 20 patients (mean age: 5.3±4.4 years) with atrial, ventricular, or atrioventricular septal defects for evaluation of cardiac structure and blood flow. Prior to cine MRI, electrocardiographycally gated MRI using multislice scquisition was performed on all patients to localize optimal slice location. Cine-MRI was obtained with a 30 deg flip angle, 15 msec echo time, and 30 msec pulse repetition time, on a 256 x 256 or 128 x 128 acquisition matrix. Abnormalities of cardiac structure were well defined in all patients by gated cardiac imaging. In 18 of the 20 patients, cine-MRI was able to detect shunt flow, visualized as a low intensity signal in comparison with the surrounding blood flow. Cine-MRI can provide not only accurate anatomy of cardiac structures but functional assessment of the cardiac chamber, wall topology and flow relations. Cine-MRI will become an important noninvasive technique for assessment of anatomy and physiology in congenital heart disease. (author)

220

MRI of articular cartilaginous lesions. MRI findings in osteoarthritis of the knee joint  

International Nuclear Information System (INIS)

An investigation was carried out to assess the usefulness of magnetic resonance imaging for imaging of the knee joint, especially for detecting articular cartilaginous lesions associated with osteoarthritis of the knee. A total of 141 patients with osteoarthritis were examined (23 males, 118 females). Their age range was 40-93 (mean age 66.2). Using radiotherapy examinations, patients were classified according to Hokkaido University Classification Criteria; 22, 49, 46, 16, and 8 patients were classified as Type I, II, III, IV and V, respectively. Articular cartilage defects were examined using MRI, and the number of such defects increased as the X-ray stage progressed. The appearance of a low signal intensity area in the bone marrow was examined using MRI, and the number of patients observed to have such areas increased as the x-ray stages progressed. JOA OA scores were significantly low for patients with meniscal tears. Patients were classified and results reviewed using MRI examinations. Classification by MRI of articular cartilage lesions correlated with the JOA OA scores. Low signal intensity areas in the bone marrow were frequently observed in advanced osteoarthritis cases, and there was correlation between FTA and MRI classifications of these areas. MRI is extremely valuable in detecting articular cartilage lesions in the knee joint, showing those lesions which cannot be detected by conventional radiography examinations. Thus, MRI is judged to be a clinically us Thus, MRI is judged to be a clinically useful method for diagnosis of osteoarthritis. (author)

221

Using in vivo Cine and 3D multi-contrast MRI to determine human atherosclerotic carotid artery material properties and circumferential shrinkage rate and their impact on stress/strain predictions.  

Science.gov (United States)

In vivo magnetic resonance image (MRI)-based computational models have been introduced to calculate atherosclerotic plaque stress and strain conditions for possible rupture predictions. However, patient-specific vessel material properties are lacking in those models, which affects the accuracy of their stress/strain predictions. A noninvasive approach of combining in vivo Cine MRI, multicontrast 3D MRI, and computational modeling was introduced to quantify patient-specific carotid artery material properties and the circumferential shrinkage rate between vessel in vivo and zero-pressure geometries. In vivo Cine and 3D multicontrast MRI carotid plaque data were acquired from 12 patients after informed consent. For each patient, one nearly-circular slice and an iterative procedure were used to quantify parameter values in the modified Mooney-Rivlin model for the vessel and the vessel circumferential shrinkage rate. A sample artery slice with and without a lipid core and three material parameter sets representing stiff, median, and soft materials from our patient data were used to demonstrate the effect of material stiffness and circumferential shrinkage process on stress/strain predictions. Parameter values of the Mooney-Rivlin models for the 12 patients were quantified. The effective Young's modulus (YM, unit: kPa) values varied from 137 (soft), 431 (median), to 1435 (stiff), and corresponding circumferential shrinkages were 32%, 12.6%, and 6%, respectively. Using the sample slice without the lipid core, the maximum plaque stress values (unit: kPa) from the soft and median materials were 153.3 and 96.2, which are 67.7% and 5% higher than that (91.4) from the stiff material, while the maximum plaque strain values from the soft and median materials were 0.71 and 0.293, which are about 700% and 230% higher than that (0.089) from the stiff material, respectively. Without circumferential shrinkages, the maximum plaque stress values (unit: kPa) from the soft, median, and stiff models were inflated to 330.7, 159.2, and 103.6, which were 116%, 65%, and 13% higher than those from models with proper shrinkage. The effective Young's modulus from the 12 human carotid arteries studied varied from 137 kPa to 1435 kPa. The vessel circumferential shrinkage to the zero-pressure condition varied from 6% to 32%. The inclusion of proper shrinkage in models based on in vivo geometry is necessary to avoid over-estimating the stresses and strains by up 100%. Material stiffness had a greater impact on strain (up to 700%) than on stress (up to 70%) predictions. Accurate patient-specific material properties and circumferential shrinkage could considerably improve the accuracy of in vivo MRI-based computational stress/strain predictions. PMID:22482663

Liu, Haofei; Canton, Gador; Yuan, Chun; Yang, Chun; Billiar, Kristen; Teng, Zhongzhao; Hoffman, Allen H; Tang, Dalin

2012-01-01

222

Leiomyoma of the sinonasal cavity: CT and MRI findings  

Energy Technology Data Exchange (ETDEWEB)

Aim: To determine the computed tomography (CT) and magnetic resonance imaging (MRI) features of leiomyoma of the sinonasal cavity. Materials and methods: Six patients with histology-proven leiomyomas in the sinonasal cavity were retrospectively reviewed. All six patients underwent CT and three patients also underwent MRI. The following imaging features were reviewed: size, margin, CT attenuation, MRI signal intensity, and lesion extent. In addition, the time-intensity curve (TIC) of dynamic contrast-enhanced (DCE) MRI and diffusion-weighted imaging (DWI) were analysed in two patients. Results: All leiomyomas had well-defined margins. The mean size was 36 mm (range 20-51 mm). On unenhanced CT, the lesions appeared isodense to cerebral grey matter in four (67%) and slightly hypodense in two (33%) patients. Leiomyomas appeared isointense On T1-weighted imaging (WI) and slightly hyperintense on T2WI in three patients. The lesions showed moderate contrast enhancement. Two patients underwent DCE MRI, and the TIC showed a rapidly enhancing and slow washout pattern. The mean apparent diffusion coefficient (ADC) value were 1.66 x 10{sup -3} mm{sup 2}/s and 1.78 x 10{sup -3} mm{sup 2}/s for the two lesions, respectively. Conclusions: Well-defined, homogeneous, expansile masses without bony erosion are typical features of leiomyoma. Althrough rare, this entity should be included in the differential diagnosis of benign tumours in this region.

Yang, B.T., E-mail: cjr.yangbentao@vip.163.co [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing (China); Wang, Z.C.; Xian, J.F.; Hao, D.P.; Chen, Q.H. [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing (China)

2009-12-15

223

MRI findings in spinal subdural and epidural hematomas  

International Nuclear Information System (INIS)

Background: Spinal hematomas are rare entities that can be the cause of an acute spinal cord compression syndrome. Therefore, an early diagnosis is of great importance. Patients and Methods: From 2001 to 2005 seven patients with intense back pain and/or acute progressive neurological deficit were studied via 1.5 T MRI (in axial and sagittal T1- and T2-weighted sequences). Follow-up MRI was obtained in six patients. Results: Four patients showed the MRI features of a hyperacute spinal hematoma (two spinal subdural hematoma [SSH] and two spinal epidural hematoma [SEH]), isointense to the spinal cord on T1- and hyperintense on T2-weighted sequences. One patient had an early subacute SEH manifest as heterogeneous signal intensity with areas of high signal intensity on T1- and T2-weighted images. Another patient had a late subacute SSH with high signal intensity on T1- and T2-weighted sequences. The final patient had a SEH in the late chronic phase being hypointense on T1- and T2-weighted sequences. Discussion: MRI is valuable in diagnosing the presence, location and extent of spinal hematomas. Hyperacute spinal hematoma and the differentiation between SSH and SEH are particular diagnostic challenges. In addition, MRI is an important tool in the follow-up in patients with conservative treatment

224

Hamstring muscle injuries in professional football: the correlation of MRI findings with return to play  

OpenAIRE

Background Hamstring injury is the single most common injury in professional football. MRI is commonly used to confirm the diagnosis and provide a prognosis of lay-off time. less thanbrgreater than less thanbrgreater thanObjective To evaluate the use of MRI as a prognostic tool for lay-off after hamstring injuries in professional football players and to study the association between MRI findings and injury circumstances. less thanbrgreater than less thanbrgreater thanMethods Prospective cohor...

Ekstrand, Jan; Healy, Jeremiah C.; Walde?n, Markus; Lee, Justin C.; English, Bryan; Ha?gglund, Martin

2012-01-01

225

MRI findings at image guided adaptive cervix cancer brachytherapy: radiation oncologist’s perspective  

OpenAIRE

Magnetic resonance imaging (MRI) represents the reference imaging modality for image guided adaptive brachytherapy (IGABT) of cervix cancer. Accurate interpretation of pre-treatment MRI is required for proper understanding of the tumor extent and topography at IGABT. Planning and optimal timing of the application begins already before treatment, and may need to be adapted during external beam irradiation (EBRT) according to additional clinical and/or radiological findings. The level of MRI ut...

Petric, Primoz; Mohammed-al-hammadi, Noora

2014-01-01

226

Tuberous sclerosis: diffusion MRI findings in the brain  

Energy Technology Data Exchange (ETDEWEB)

Diffusion MRI has mainly been used for detection of acute ischemia, and for distinction of cytotoxic and vasogenic edema. We applied diffusion MRI in patients with tuberous sclerosis in order to evaluate diffusion imaging characteristics of parenchymal changes. Five children with known tuberous sclerosis were included in this study. The MRI examinations were performed on a 1.5-T MR unit. Diffusion MRI was obtained using the echo-planar imaging sequence. Apparent diffusion coefficient (ADC) values from the abnormal brain parenchyma were calculated directly from automatically generated ADC maps. Seven normal children were available for comparison. In this control group the mean ADC value of the normal white matter was 0.84{+-}0.12 x 10{sup -3} mm{sup 2}/s. In tuberous sclerosis patients the mean ADC value of the white matter hamartomas (n=20) was apparently high (1.52{+-}0.24 x 10{sup -3} mm{sup 2}/s) compared with that of normal white matter. The ADC value of calcified hamartomas was ''zero''. The ADC value within a giant cell tumor was 0.89 x 10{sup -3} mm{sup 2}/s, similar to that of normal cerebral white matter. The ADC maps were superior to b=1000 s/mm{sup 2} (true diffusion) images with respect to lesion evaluation, and they provided mathematical information on tissue integrity. With respect to detection of the exact numbers and sizes of the parenchymal hamartomas fluid-attenuated inversion recovery images were superior to ADC maps. It is believed that diffusion MRI can be useful in evaluation of various parenchymal changes associated with tuberous sclerosis. Further studies on tuberous sclerosis, and on various brain lesions, would provide increasing data on this relatively new MRI sequence. (orig.)

Sener, R.N. [Department of Radiology, Ege University Hospital, Izmir (Turkey)

2002-01-01

227

Tuberous sclerosis: diffusion MRI findings in the brain  

International Nuclear Information System (INIS)

Diffusion MRI has mainly been used for detection of acute ischemia, and for distinction of cytotoxic and vasogenic edema. We applied diffusion MRI in patients with tuberous sclerosis in order to evaluate diffusion imaging characteristics of parenchymal changes. Five children with known tuberous sclerosis were included in this study. The MRI examinations were performed on a 1.5-T MR unit. Diffusion MRI was obtained using the echo-planar imaging sequence. Apparent diffusion coefficient (ADC) values from the abnormal brain parenchyma were calculated directly from automatically generated ADC maps. Seven normal children were available for comparison. In this control group the mean ADC value of the normal white matter was 0.84±0.12 x 10-3 mm2/s. In tuberous sclerosis patients the mean ADC value of the white matter hamartomas (n=20) was apparently high (1.52±0.24 x 10-3 mm2/s) compared with that of normal white matter. The ADC value of calcified hamartomas was ''zero''. The ADC value within a giant cell tumor was 0.89 x 10-3 mm2/s, similar to that of normal cerebral white matter. The ADC maps were superior to b=1000 s/mm2 (true diffusion) images with respect to lesion evaluation, and they provided mathematical information on tissue integrity. With respect to detection of the exact numbers and sizes of the parenchymal hamartomas fluid-attenuated inversion recovery images were superior to ADC maps. overy images were superior to ADC maps. It is believed that diffusion MRI can be useful in evaluation of various parenchymal changes associated with tuberous sclerosis. Further studies on tuberous sclerosis, and on various brain lesions, would provide increasing data on this relatively new MRI sequence. (orig.)

228

Mesenchymal chondrosarcoma of the orbit: CT and MRI findings  

Energy Technology Data Exchange (ETDEWEB)

Aim: To describe the computed tomography (CT) and magnetic resonance imaging (MRI) features of orbital mesenchymal chondrosarcomas (MCSs). Materials and methods: Six patients with histology-confirmed MCSs of the orbit were retrospectively reviewed. All six patients underwent CT and MRI. Imaging studies were evaluated for the following: (a) tumour location, (b) configuration, size, and margin, (c) CT attenuation and MRI signal intensity, and (d) secondary manifestations. Additionally, the time-intensity curve (TIC) of dynamic contrast-enhanced (DCE) MRI were analysed in five patients. Results: Two MCSs arose in the right orbit and four in the left orbit. Five MCSs were located in the retrobulbar intraconal space and one in the extraconal space. All the lesions displayed a lobulate configuration and had a well-defined margin. The mean maximum diameter was 25.8 mm (range 15-36 mm). On unenhanced CT, the lesions appeared isodense to grey matter in six patients, with calcifications in five. Two patients showed inhomogeneous, moderate enhancement on enhanced CT. Six MCSs appeared isointense on T1-weighted imaging and heterogeneously isointense on T2-weighted imaging. The lesions showed significantly heterogeneous contrast enhancement. Five patients had DCE MRI and the TICs showed a rapidly enhancing and rapid washout pattern (type III). The following features were also detected: compression of the extra-ocular muscle (six patients, 100%); displacement of the optic nerve (five patients, 83.3%); and encasing globe (three patients, 50%). Conclusions: A well-defined, lobulate orbital mass with calcification on CT and, marked heterogeneous enhancement and type III TIC on MRI are highly suspicious of orbital MCSs.

Yang, B.T., E-mail: cjr.yangbentao@vip.163.com [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing (China); Wang, Y.Z.; Wang, X.Y.; Wang, Z.C. [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing (China)

2012-04-15

229

CT and MRI findings of calcified spinal meningiomas: correlation with pathological findings  

International Nuclear Information System (INIS)

This study was designed to present characteristic CT and MR findings of calcified spinal meningiomas that correlate with pathological findings and to assess the efficacy of CT for the detection of calcifications within a mass in comparison to MRI. Between 1998 and 2009, 10 out of 11 patients who had pathologically confirmed psammomatous meningiomas showed gross calcifications on CT images and were included in this study. On CT scans of the 10 patients, the distribution pattern, morphology and number of calcifications within masses were evaluated. MRI was performed in seven patients and signal intensities of masses were assessed. The pathological results analyzed semi-quantitatively were compared with the density or the size of calcifications within a mass as seen on a CT scan. Seven of 10 masses were located at the thoracic spine level. Eight masses had intradural locations. The other two masses had extradural locations. Four masses were completely calcified based on standard radiographs and CT. Symptoms duration, the size of the mass and size or number of calcifications within a mass had no correlation. The location, size, and distribution pattern of calcifications within masses were variable. On MR images, signal intensity of calcified tumor varied on all imaging sequences. All the masses enhanced after injection of intravenous contrast material. A calcified meningioma should be first suggested when extradural or intradural masses located in the spine contain calcifmasses located in the spine contain calcifications regardless of the size or pattern as depicted on CT, especially in the presence of enhancement as seen on MR images. (orig.)

230

CT and MRI findings in patients with neuroinfections  

International Nuclear Information System (INIS)

Although in most patients a diagnosis of neuroinfection is not based on the results of brain imaging, there is a trend to perform MRI or CT on any patient in whom such infection is suspected. However, in selected cases, especially in patients with brain abscess or with herpetic encephalitis, brain CT and/or MRI are essential for diagnosis. Therefore we decided to analyze the results of computed tomography and magnetic resonance imaging of the brains of patients with neuroinfections and to assess the usefulness of these imaging methods in clinical practice. Brain imaging (CT and/or MRI) was performed in 106 cases (62 purulent and 44 aseptic ingoencephalitis patients). The results were analyzed in subgroups of patients with different etiology of neuroinfection. In 40 of the 58 patients (68.9%) with purulent meningoencephalitis on whom computed tomography was made, the image revealed the pathology. In the remaining 18 cases (31.1%) the results were normal. In all 4 patients on whom only MRI was done, the results were abnormal (4/4, 100%). Among the 41 patients with aseptic meningoencephalitis on whom computed tomography was done, the pathology was found in 11 (26.8%). Of the 20 patients who underwent brain MRI, the pathology was depicted in 12 (12/20, 60.0%). In 4 of the 24 patients (16.7%) with aseptic meningoencephalitis on whom only computed tomography was done, the results were abnormal. In 2 of the 3 patients (66.7%) on whom MRI was done as the only radiological exa MRI was done as the only radiological examination, the results were abnormal. The pathology was found on the radiograms of 11 of the 17 patients (64.7%) in whom both imaging methods were used. In the remaining 6 of these 17 cases (6/17, 35.3%) neither CT nor MRI revealed any abnormality. Altogether, of the 44 patients with aseptic meningoencephalitis in whom brain imaging was performed, pathology was depicted in 17 (38.7%). 1. The high percentage of abnormal CT and MR images in patients with meningoencephalitis warrants the use of brain imaging in patients with severe clinical course of the disease and in patients in whom diagnosis is difficult. 2. Imaging techniques are most efficient in patients with herpes simplex and tuberculous encephalitis. 3. Our observations suggest that in patients with aseptic neuroinfection, magnetic resonance is of greater value than computed tomography imaging. (author)

231

Wallerian degeneration of brain: MRI and CT findings  

International Nuclear Information System (INIS)

Wallerian degeneration is well known as the anterograde degeneration of axon and their accompanying myelin sheath from injury to the proximal portion of the axon or its cell body. The most common cause of wallerian degeneration is cerebral infarction. Authors experienced three patients with old hemispheric infarct with typical wallerian degeneration in the brain stem, which was demonstrated by magnetic resonance imaging (MRI) in two cases and CT in one case. This report demonstrates the wallerian degeneration in the corticospinal tract in on the MRI and CT with the brief review of literatures

232

Correlation of MRI findings with clinical findings of trochanteric pain syndrome  

International Nuclear Information System (INIS)

Greater trochanter pain syndrome due to tendinopathy or bursitis is a common cause of hip pain. The previously reported magnetic resonance (MR) findings of trochanteric tendinopathy and bursitis are peritrochanteric fluid and abductor tendon abnormality. We have often noted peritrochanteric high T2 signal in patients without trochanteric symptoms. The purpose of this study was to determine whether the MR findings of peritrochanteric fluid or hip abductor tendon pathology correlate with trochanteric pain. We retrospectively reviewed 131 consecutive MR examinations of the pelvis (256 hips) for T2 peritrochanteric signal and abductor tendon abnormalities without knowledge of the clinical symptoms. Any T2 peritrochanteric abnormality was characterized by size as tiny, small, medium, or large; by morphology as feathery, crescentic, or round; and by location as bursal or intratendinous. The clinical symptoms of hip pain and trochanteric pain were compared to the MR findings on coronal, sagittal, and axial T2 sequences using chi-square or Fisher's exact test with significance assigned as p<0.05. Clinical symptoms of trochanteric pain syndrome were present in only 16 of the 256 hips. All 16 hips with trochanteric pain and 212 (88%) of 240 without trochanteric pain had peritrochanteric abnormalities (p=0.15). Eighty-eight percent of hips with trochanteric symptoms had gluteus tendinopathy while 50% of those without symptoms had such findings (p=0.004). Other than tendinopathy,ndings (p=0.004). Other than tendinopathy, there was no statistically significant difference between hips with or without trochanteric symptoms and the presence of peritrochanteric T2 abnormality, its size or shape, and the presence of gluteus medius or minimus partial thickness tears. Patients with trochanteric pain syndrome always have peritrochanteric T2 abnormalities and are significantly more likely to have abductor tendinopathy on magnetic resonance imaging (MRI). However, although the absence of peritrochanteric T2 MR abnormalities makes trochanteric pain syndrome unlikely, detection of these abnormalities on MRI is a poor predictor of trochanteric pain syndrome as these findings are present in a high percentage of patients without trochanteric pain. (orig.)

233

Correlation of MRI findings with clinical findings of trochanteric pain syndrome  

Energy Technology Data Exchange (ETDEWEB)

Greater trochanter pain syndrome due to tendinopathy or bursitis is a common cause of hip pain. The previously reported magnetic resonance (MR) findings of trochanteric tendinopathy and bursitis are peritrochanteric fluid and abductor tendon abnormality. We have often noted peritrochanteric high T2 signal in patients without trochanteric symptoms. The purpose of this study was to determine whether the MR findings of peritrochanteric fluid or hip abductor tendon pathology correlate with trochanteric pain. We retrospectively reviewed 131 consecutive MR examinations of the pelvis (256 hips) for T2 peritrochanteric signal and abductor tendon abnormalities without knowledge of the clinical symptoms. Any T2 peritrochanteric abnormality was characterized by size as tiny, small, medium, or large; by morphology as feathery, crescentic, or round; and by location as bursal or intratendinous. The clinical symptoms of hip pain and trochanteric pain were compared to the MR findings on coronal, sagittal, and axial T2 sequences using chi-square or Fisher's exact test with significance assigned as p<0.05. Clinical symptoms of trochanteric pain syndrome were present in only 16 of the 256 hips. All 16 hips with trochanteric pain and 212 (88%) of 240 without trochanteric pain had peritrochanteric abnormalities (p=0.15). Eighty-eight percent of hips with trochanteric symptoms had gluteus tendinopathy while 50% of those without symptoms had such findings (p=0.004). Other than tendinopathy, there was no statistically significant difference between hips with or without trochanteric symptoms and the presence of peritrochanteric T2 abnormality, its size or shape, and the presence of gluteus medius or minimus partial thickness tears. Patients with trochanteric pain syndrome always have peritrochanteric T2 abnormalities and are significantly more likely to have abductor tendinopathy on magnetic resonance imaging (MRI). However, although the absence of peritrochanteric T2 MR abnormalities makes trochanteric pain syndrome unlikely, detection of these abnormalities on MRI is a poor predictor of trochanteric pain syndrome as these findings are present in a high percentage of patients without trochanteric pain. (orig.)

Blankenbaker, Donna G.; Ullrick, Steven R.; Davis, Kirkland W.; De Smet, Arthur A. [University of Wisconsin School of Medicine and Public Health, Department of Radiology, Madison, WI (United States); Haaland, Ben; Fine, Jason P. [University of Wisconsin School of Medicine and Public Health, Departments of Biostatistics and Medical Informatics and Statistics, Madison, WI (United States)

2008-10-15

234

Comparison of clinical and MRI findings in Chiari malformation  

International Nuclear Information System (INIS)

Chiari malformation (CM) using magnetic resonance imaging (MRI) which allows to establish its type and to determine the ratio and characteristics of clinical picture of different types of CM was studied. The characteristics of anatomical varieties of CM were determined. Disturbances of liquor dynamics (including intracranial hypertension hydrocephalus) were noted. Combination of CM and syringomyelia and other cerebral and spinal diseases were revealed

235

MRI findings with periventricular leukomalacia. Correlation with neurological development  

Energy Technology Data Exchange (ETDEWEB)

In 22 infants with PVL, who were born at 35 weeks gestational age or less, correlation between severity of white matter lesions on MRI and developmental quotient (DQ) of infants was studied. MRI was obtained later than 7 months of age and the severity of white matter lesions was classified as follows: Group I: periventricular white matter is focally affected (n=7), Group II: periventricular white matter is diffusely affected (n=10), and Group III: subcortical white matter is also affected (n=5). Perinatal characteristics including gestational weeks, birth weight, Apgar score, procedure of delivery, and duration of mechanical ventilation revealed no significant differences between the groups. Seventeen infants developed cerebral palsy, while the other 5 infants (4 in Group I, 1 in Group II) showed normal development at 1 year of age, MRI of 4 among these 5 infants only revealed unilateral cysts around the anterior horn of lateral ventricles. Enjoji developmental test showed significant differences in gross motor DQ between Group I and III at both 1 and 2 corrected ages. Although more quantitative criteria will be required for precise classification, it is suggested that the severity of the white matter lesions on MRI is well correlated with gross motor development in PVL. (author)

Uehara, Hisakazu; Yoshioka, Hiroshi; Hasegawa, Koh; Doi, Yasuo; Matsuo, Yasutaka; Murata, Miyuki; Sawada, Tadashi [Kyoto Prefectural Univ. of Medicine (Japan); Kotani, Hiromi; Goma, Hideyo

1998-08-01

236

MRI findings with periventricular leukomalacia. Correlation with neurological development  

International Nuclear Information System (INIS)

In 22 infants with PVL, who were born at 35 weeks gestational age or less, correlation between severity of white matter lesions on MRI and developmental quotient (DQ) of infants was studied. MRI was obtained later than 7 months of age and the severity of white matter lesions was classified as follows: Group I: periventricular white matter is focally affected (n=7), Group II: periventricular white matter is diffusely affected (n=10), and Group III: subcortical white matter is also affected (n=5). Perinatal characteristics including gestational weeks, birth weight, Apgar score, procedure of delivery, and duration of mechanical ventilation revealed no significant differences between the groups. Seventeen infants developed cerebral palsy, while the other 5 infants (4 in Group I, 1 in Group II) showed normal development at 1 year of age, MRI of 4 among these 5 infants only revealed unilateral cysts around the anterior horn of lateral ventricles. Enjoji developmental test showed significant differences in gross motor DQ between Group I and III at both 1 and 2 corrected ages. Although more quantitative criteria will be required for precise classification, it is suggested that the severity of the white matter lesions on MRI is well correlated with gross motor development in PVL. (author)

237

MRI findings in the upper cervical spine of rheumatoid arthritis  

International Nuclear Information System (INIS)

In 55 patients with rheumatoid arthritis associated with upper cervical spine abnormality, the presence or absence of medullary and upper cervical pressures was examined on sagittal MRI scans. Atlanto-dental anterior incomplete dislocation and horizontal dislocation were imaged concurrently with X-rays. For horizontal dislocation, an abnormal Redlund-Johnell value and a Ranawat value of 7 mm or less were always associated with medullary pressure as seen on MRI. For anterior incomplete dislocation, upper cervical pressure was always associated when a space available for the spinal cord was 13 mm or less or frequently associated when the atlanto-dental interval was 8 mm or more. Many of the patients with the upper cervical abnormalities complained of occipital or cervical pain. The pain was always encountered in patients with an abnormal Redlund-Johnell value. Roentgenography of the cervical spine confirmed MRI-proven medullary or upper cervical pressure, suggesting the potential of MRI in the treatment of rheumatoid arthritis. (Namekawa, K)

238

Spinal cord and cauda equina MRI findings in metachromatic leukodystrophy: case report  

International Nuclear Information System (INIS)

Metachromatic leukodystrophy (MLD) is an autosomal recessive disease with well-documented intracranial findings on neuroimaging both by computed tomography (CT) and MRI. We describe the first case of late infantile MLD with spinal involvement revealed by MRI as marked contrast enhancement of nerve roots at the level of the cauda equina. (orig.)

239

A case report of Castleman disease in the neck: CT and MRI finding  

International Nuclear Information System (INIS)

Castleman disease is rare lymphoproliferative disorder of uncertain cause, which most commonly involves mediastinum and rarely affects retroperitoneal, axillary or cervical lymph nodes. Authors present CT and MRI findings of a case of Castleman disease involving cervical lymph nodes. On CT and MRI, there were multiple lymph nodes enlargement with homogeneous enhancement along the bilateral internal jugular and spinal accessory lymph node chain

240

MRI findings in neuro-Behcet's disease  

Energy Technology Data Exchange (ETDEWEB)

AIM: To evaluate the pattern and site of involvement in neuro-Behcet's disease (NBD). MATERIALS AND METHODS: Twenty-one patients with NBD were evaluated. Using 1.5T magnetic resonance imaging (MRI), T1-weighted axial and sagittal images, gadolinium enhanced axial and coronal images and T2-weighted axial images were obtained. RESULTS: The brainstem, basal ganglia, cerebral white matter, internal capsule, thalamus and spinal cord were involved in eighteen, nine, nine, seven, six and two patients, respectively. In nine patients with cerebral white matter involvement, four had subcortical involvement and three had periventricular involvement, in addition to two patients with focal deep white matter lesions. Among the brainstem lesions, pons involvement was seen in fourteen patients, all had ventrally located lesions, and nine had tegmental involvement. Midbrain involvement was seen in fourteen patients; the cerebral peduncle was involved in 11 of these. Five patients had brainstem atrophy: two cases were demonstrated at initial MRI, the other three cases were seen on follow-up MRI. Pyramidal signs, the most common neurological signs, were demonstrated in fourteen patients. Follow-up MRI was obtained 10 days to 20 months after the initial MRI in eight cases; all showed changes in size, shape and site of involvement. After gadolinium enhancement, thirteen patients demonstrated mottled non-confluent enhancement in the brainstem (eight patients), posterior limb of the internal capsule (three patients), pachymeninges (two patients) and spinal cord (two patients). CONCLUSION: NBD manifests a reversible course, but chronic NBD may result in brainstem atrophy. Characteristic involvement along the corticospinal tract is well correlated with neurological signs. Lee, S. H. et al. (2001)

Lee, Sang Hoon; Yoon, Pyeong Ho; Park, Sang Joon; Kim, Dong Ik

2001-06-01

241

Can pathoanatomical pathways of degeneration in lumbar motion segments be identified by clustering MRI findings  

DEFF Research Database (Denmark)

Magnetic Resonance Imaging (MRI) is the gold standard for detailed visualisation of spinal pathological and degenerative processes, but the prevailing view is that such imaging findings have little or no clinical relevance for low back pain. This is because these findings appear to have little association with treatment effects in clinical populations, and mostly a weak association with the presence of pain in the general population.However, almost all research into these associations is based on the examination of individual MRI findings, despite its being very common for multiple MRI findings to coexist. Therefore, this proof-of-concept study investigated the capacity of a multivariable statistical method to identify clusters of MRI findings and for those clusters to be grouped into pathways of vertebral degeneration.

Jensen, Rikke Krüger; Jensen, Tue S

2013-01-01

242

The MRI findings of a de Garengeot hernia.  

LENUS (Irish Health Repository)

The presence of the appendix within a femoral hernia is rare. It was first described by the French surgeon Jacques Croissant de Garengeot in 1731. This phenomenon accounts for 0.8-1% of all femoral hernias. Acute appendicitis occurring within a femoral hernia is even rarer and is difficult to diagnose pre-operatively. This type of hernia is termed a de Garengeot hernia. The ultrasonographic and CT imaging features of de Garengeot hernias have been described previously. We report a case of a 57-year-old female who presented with a painful right-sided groin mass. She underwent MRI of the inguinal region, which successfully diagnosed this rare hernia pre-operatively. To our knowledge, this is the first description of a de Garengeot hernia diagnosed using MRI.

Halpenny, D

2012-03-01

243

The MRI findings of a de Garengeot hernia.  

Science.gov (United States)

The presence of the appendix within a femoral hernia is rare. It was first described by the French surgeon Jacques Croissant de Garengeot in 1731. This phenomenon accounts for 0.8-1% of all femoral hernias. Acute appendicitis occurring within a femoral hernia is even rarer and is difficult to diagnose pre-operatively. This type of hernia is termed a de Garengeot hernia. The ultrasonographic and CT imaging features of de Garengeot hernias have been described previously. We report a case of a 57-year-old female who presented with a painful right-sided groin mass. She underwent MRI of the inguinal region, which successfully diagnosed this rare hernia pre-operatively. To our knowledge, this is the first description of a de Garengeot hernia diagnosed using MRI. PMID:22391502

Halpenny, D; Barrett, R; O'Callaghan, K; Eltayeb, O; Torreggiani, W C

2012-03-01

244

MRI and CT findings of adult Down's syndrome  

International Nuclear Information System (INIS)

Cranial CT and MRI were performed in 29 adult patients with Down's syndrome aged from 20 to 46 years to examine early aging. Morphological changes with aging, such as brain atrophy and ventricular enlargement, were generally sparse; however, calculi of the basal nucleus and lesions of deep-seated white matter were significantly increased with aging. The pallidum and putamen were shown as low intensity signals on T2-weighted images in many of patients in their fourties, suggesting their involvement in the occurrence of dyskinesia and parkinsonism symptoms that are likely to occur in the elderly. Localized changes, as shown on CT and MRI, may reflect abnormally early occurrence of aging, which precedes morphological changes such as brain atrophy. (N.K.)

245

Correlation of MRI and histopathology findings in inflammatory skin diseases  

International Nuclear Information System (INIS)

Purpose: Can spatial and contrast resolution be achieved with currently available MR devices for the successful assessment of inflammatory diseases of the skin? Results: In 15 of 20 cases, high resolution MRI allowed a correct classification of the visualised dermal and subcutaneous patterns, in accordance with the histological work-up of the corresponding specimen. Due to the still only suboptimal spatial and contrast resolution the structure of the epidermis could not be assessed adequately. Determination of contrast enhancement or non-enhancement after administration of intravenous contrast agent provided information on the degree of tissue perfusion in 19 patients, which complemented the morphological assessment. Conclusion: High resolution MRI allows to identify non-invasively histological main patterns of inflammatory skin diseases. However, final diagnosis often depends on higher microscopic resolution and special staining. (orig./AJ)

246

Association between pathological and MRI findings in multiple sclerosis.  

Science.gov (United States)

The identification of pathological processes that could be targeted by therapeutic interventions is a major goal of research into multiple sclerosis (MS). Pathological assessment is the gold standard for such identification, but has intrinsic limitations owing to the limited availability of autopsy and biopsy tissue. MRI has gained a leading role in the assessment of MS because it allows doctors to obtain an ante mortem picture of the degree of CNS involvement. A number of correlative pathological and MRI studies have helped to define in vivo the pathological substrates of MS in focal lesions and normal-appearing white matter, not only in the brain, but also in the spinal cord. These studies have resulted in the identification of aspects of pathophysiology that were previously neglected, including grey matter involvement and vascular pathology. Despite these important achievements, numerous open questions still need to be addressed to resolve controversies about how the pathology of MS results in fixed neurological disability. PMID:22441196

Filippi, Massimo; Rocca, Maria A; Barkhof, Frederik; Brück, Wolfgang; Chen, Jacqueline T; Comi, Giancarlo; DeLuca, Gabriele; De Stefano, Nicola; Erickson, Bradley J; Evangelou, Nikos; Fazekas, Franz; Geurts, Jeroen J G; Lucchinetti, Claudia; Miller, David H; Pelletier, Daniel; Popescu, Bogdan F Gh; Lassmann, Hans

2012-04-01

247

MRI findings in the patients with the presumptive clinical diagnosis of Tolosa-Hunt syndrome  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study was to present our experience in MRI diagnosis of 23 patients with the clinical findings suggesting Tolosa-Hunt syndrome (THS). Cranial MRI studies of the patients with a clinical history of at least one episode of unilateral or bilateral orbital and periorbital pain, and associated paresis of one or more of third to sixth cranial nerves, were performed on a 1.5-T MRI scanner. Whereas 5 patients had the diagnosis of THS, paracavernous meningiomas in 4 patients, pituitary macroadenomas with cavernous sinus infiltration in 3 patients, Meckel's cave neurinoma in 1 patient, and suprasellar epidermoid in 1 patient were surgically proven MRI findings. Other pathological MRI findings were leptomeningeal metastases in 3 patients, granulomatous pachymeningitis sequelae in 2 patients, and aneurysm with compression on cavernous sinus in 1 patient. Three patients had normal MRI findings. The incidence of radiologically proven diagnosis of THS among the patients with the clinical findings suggesting THS seemed to be low in our study. In conclusion, MRI is the most valuable imaging technique to distinguish THS from other THS-like entities, and permits a precise assessment, management, and therapeutic planning of the underlying pathological conditions. (orig.)

Cakirer, Sinan [Department of Radiology, Neuroradiology Section, Istanbul Sisli Etfal Hospital, 81120 Istanbul (Turkey)

2003-01-01

248

MRI findings in the patients with the presumptive clinical diagnosis of Tolosa-Hunt syndrome  

International Nuclear Information System (INIS)

The aim of this study was to present our experience in MRI diagnosis of 23 patients with the clinical findings suggesting Tolosa-Hunt syndrome (THS). Cranial MRI studies of the patients with a clinical history of at least one episode of unilateral or bilateral orbital and periorbital pain, and associated paresis of one or more of third to sixth cranial nerves, were performed on a 1.5-T MRI scanner. Whereas 5 patients had the diagnosis of THS, paracavernous meningiomas in 4 patients, pituitary macroadenomas with cavernous sinus infiltration in 3 patients, Meckel's cave neurinoma in 1 patient, and suprasellar epidermoid in 1 patient were surgically proven MRI findings. Other pathological MRI findings were leptomeningeal metastases in 3 patients, granulomatous pachymeningitis sequelae in 2 patients, and aneurysm with compression on cavernous sinus in 1 patient. Three patients had normal MRI findings. The incidence of radiologically proven diagnosis of THS among the patients with the clinical findings suggesting THS seemed to be low in our study. In conclusion, MRI is the most valuable imaging technique to distinguish THS from other THS-like entities, and permits a precise assessment, management, and therapeutic planning of the underlying pathological conditions. (orig.)

249

Wildervanck or cervico-oculo-acoustic syndrome and MRI findings.  

OpenAIRE

In 1952, Wildervanck described the first case of what he styled the cervico-oculo-acoustic (COA) syndrome. This comprises Klippel Feil's (KF) anomaly (congenitally fused cervical vertebrae), congenital sensorineural deafness and Duane's retraction syndrome (deficient abduction with retraction on adduction). Since that original paper, there have been further reports describing this triad, either completely or incompletely. A further case of this syndrome is reported and the first report of MRI...

Hughes, P. J.; Davies, P. T.; Roche, S. W.; Matthews, T. D.; Lane, R. J.

1991-01-01

250

UCSF study finds breast MRI helps predict chemotherapy's effectiveness  

Science.gov (United States)

Magnetic resonance imaging (MRI) provides an indication of a breast tumor's response to pre-surgical chemotherapy significantly earlier than possible through clinical examination, according to a new study published online in the journal Radiology. Women with breast cancer often undergo chemotherapy prior to surgery. Research has shown that women who receive this treatment, known as neoadjuvant chemotherapy, are more likely to achieve breast conservation than those receiving chemotherapy after surgery.

251

The MSCT and MRI findings of collecting duct carcinoma  

International Nuclear Information System (INIS)

Aim: To characterize the multi-section computed tomography (MSCT) and magnetic resonance imaging (MRI) features of collecting duct carcinoma (CDC). Materials and methods: Twenty patients with CDC were studied retrospectively using MSCT (n = 20), and MSCT and MRI (n = 5). MSCT and MRI were undertaken to investigate tumour location, size, radiodensity, cystic or solid appearance, calcification, capsule, signal, enhancement pattern, and metastases. Results: Tumours (mean diameter 3.6 ± 1.7 cm) were solitary (20/20), solid (18/20), had cystic components (12/20), calcifications (12/20), poorly defined (18/20), were centred in the medulla (20/20), compressed the renal pelvis (12/20), and had lymph node metastases (2/20). On unenhanced computed tomography (CT), the radiodensity of the CDC was greater than that of the normal renal cortex or medulla (43.8 ± 2.4 versus 37.6 ± 5.1 or 32.6 ± 4.1, p = 0.041, n = 20). Five patients with CDC underwent MRI, which revealed cystic components (4/5), poorly defined CDC (5/5), and none of the patients had lymph node metastasis. The CDC was isointense on T1-weighted imaging, and iso- or hypointense on T2-weighted imaging. Enhancement was lower within the CDC than the renal cortex and medulla during all enhanced phases (p = 0.032, 0.001, 0.018, respectively, n = 20). Conclusion: CDC should be considered when a renal tumour is centred in the medulla, with increased radiodensity on unenhanced CT and reduced enhancement compared to the adjacent cortex or medulla

252

MRI findings on lacunar infarction with no clinical symptoms  

International Nuclear Information System (INIS)

The purpose of this study was to examine how lacunar infarction developed and what its characteristics were. As this disease had little noticeable clinical symptoms and is likely to draw less attention than other types of cerebrovascular diseases like panhemispheric infarction, it's difficult to make an early diagnosis of it or treat it successfully. The subjects in this study were 196 people who showed no clinical symptoms and took a MRI test. When the MRI test data were analyzed, signal intensity and the part where that disease was detected were primarily taken into account. As a result, it's found that 116 people had no lacunar infarction and 80 people suffered from that disease, including 13 with very mild lacunar infarction, 41 with mild lacunar infarction and 26 with lacunar infarction. However, very mild and mild lacunar infarction could not be viewed as clinically significant cases, and only 26 people, which accounted for 13 percent of the subjects, should be considered to be diagnosed with lacunar infarction. The most common part where that disease was found was white matter and basal ganglia, regardless of gender. Accordingly, those who are exposed to health hazards such as hypertension or diabetes should take a MRI test to prevent cerebrovascular diseases that might be caused by those illnesses

253

Cystic angiomatosis with splenic involvement: unusual MRI findings  

Energy Technology Data Exchange (ETDEWEB)

Cystic angiomatosis is a rare disorder with a poor prognosis. We describe a case of a 33-year-old woman who presented with longstanding bone pain, hemolytic anemia, and an enlarged spleen. Radiologically, multiple osseous lesions with a mixed pattern of lytic and sclerotic areas were seen within the shoulders, spine, and pelvis. On CT and MRI of the abdomen, the spleen was markedly enlarged, with internal hyperdense foci on non-contrast CT scan, corresponding to low signal intensity areas on all MR pulse sequences. After administration of contrast, a mottled enhancement pattern throughout the entire spleen was seen both on CT and MRI. Cystic angiomatosis was proven by histological analysis of a biopsy specimen of an involved vertebra and histopathological examination of the spleen after subsequent splenectomy. This is the first report of a patient with disseminated cystic angiomatosis with splenic involvement in which the MRI features differ from the previous reports. Instead of the usual pattern consisting of multiple well-defined cystic lesions, a diffuse involvement replacing the entire spleen, with heterogeneous signal intensities on T2-weighted images and heterogeneous enhancement pattern, was seen in our patient. (orig.)

Vanhoenacker, F.M. [Dept. of Radiology, Univ. Hospital Antwerp, Edegem (Belgium); Dept. of Radiology, AZ St-Maarten, Campus Duffel, Duffel (Belgium); Schepper, A.M. [Dept. of Radiology, Univ. Hospital Antwerp, Edegem (Belgium); Raeve, H. [Dept. of Pathology, Univ. Hospital Antwerp, Edegem (Belgium); Berneman, Z. [Dept. of Hematology, Univ. Hospital Antwerp, Edegem (Belgium)

2003-12-01

254

Findings of anomalous pulmonary venous return using MRI.  

Science.gov (United States)

This study represents a preliminary retrospective assessment of the value of spin-echo magnetic resonance imaging (MRI) in detecting and describing total or partial anomalous pulmonary venous return (APVR). MRI was performed in 21 cases of APVR; orthogonal planes were used in all. Of the 21 cases, 19 were classified as total APVR (TAPVR) and two were partial APVR (PAPVR). Of the 19 cases of TAPVR, seven supracardiac, nine cardiac, one infracardiac and two mixed type were noted. The detection rate of each pulmonary vein combined in all three planes was 57% in the right superior pulmonary vein (RSPV), 62% in the left superior pulmonary vein (LSPV), 76% in the right inferior pulmonary vein (RIPV), and 86% in the left inferior pulmonary vein (LIPV). The axial plane was most effective (RSPV: 38%; LSPV: 52%; RIPV: 71%; LIPV: 81%). The coronal plane offered a better detection rate than the axial plane in RSPV (43%) and additional information of bronchial and visceral situs. Imaging of the combined axial and coronal planes was sufficient to evaluate each individual pulmonary vein. The sagittal plane gave no additional information in this respect. Accurate identification of pulmonary venous confluence and anomalous pulmonary venous channel was 95% (20/21). Limitation of echocardiography and and angiocardiography makes cardiac MRI important in assessing pulmonary vein and pulmonary venous confluence. It obviates the need for invasive angiocardiography and is an important supplement to an inadequate echo. PMID:7858433

Chang, Y C; Li, Y W; Liu, H M; Wang, T C; Wang, J K; Wu, M H; Wu, C Y; Su, C T; Tsang, Y M; Hsu, J C

1994-06-01

255

MRI findings of lipoma arborescens of the knee in a child: case report  

International Nuclear Information System (INIS)

Lipoma arborescens is an intraarticular lesion characterized by a frond-like mass of mature fat cells, usually involving the suprapatellar bursa. It is a rare lesion in adults and extremely rare in children. Because of the fatty nature of the lesion, the MRI findings of arborescens are specific. We present the MRI findings of lipoma arborescens of the knee in a 9-year-old girl. (orig.)

256

Cine e identidades virtuales  

Directory of Open Access Journals (Sweden)

Full Text Available The subject is the ability the cinema has performed - since its very begining - as a creation instrument of national and transnational identities. In the first place, it covers Spanish cinema since 1938 and right after the end of the Spanish Civil War, II World War Italian-German cinema, Eisenstein’s, Leni Riefenstahl’s, Griffth’s and Ford’s cinema, the role American war and science fiction productions played, as well as the comedies dealing with the divided Berlin subject. The role of computers and video-games and the new cinema positionings that forecast the end of what is real, is studied through films such as Tron, The Lawnmower Man, Johnny Mnemonic, Ghost in the shell, Simone o Matrix.Se estudia la capacidad del cine desde sus orígenes como instrumento de generación de identidades nacionales y transnacionales. Se realiza, en primer lugar, un recorrido por el cine español desde 1938 y tras el final de la guerra civil, el cine italo-alemán de la II Guerra Mundial, el cine de Eisenstein, Leni Riefenstahl, Griffth y Ford, y el papel que jugaron las producciones norteamericanas bélicas y de ciencia ficción, así como las comedias sobre el Berlín dividido. El papel de los ordenadores y los videojuegos, y los nuevos planteamientos cinematográficos que pronostican el final de lo real se estudia a través de películas como Tron, El cortador de césped, Johnny Mnemonic, Ghost in the shell, Simone o Matrix.

Labrador Ben, Julia María

2006-12-01

257

Brain lesions in neurofibromatosis: clinical and MRI findings  

International Nuclear Information System (INIS)

Neurofibromatosis is the commonest neuroectodermal disease. It is characterized by dysplasias and/or tumors of organs and tissues derived from the embryonic ectoderm, and most frequently presents with nervous system and cutaneous lesions. It can be classified as neurofibromatosis type 2 (NF-2 or bilateral acoustic neurofibromatosis). In order to assess clinical presentation of the disease and diagnostic value of Magnetic Resonance Imaging (MRI), the authors retrospectively evaluated the clinical records and the cranial MR studies of 21 patients with neurofibromatosis (18 with NF-1 and 3 with NF-2). Distinctive abnormalities between the two types were found in both clinical presentation and MR studies. Clinically, NF-1 patients presented most often with blindness, while NF-2 patients were deaf and had fewer cutaneous lesions. The evaluation of MR studies showed that NF-1 patients were more likely to be affected with intracranial gliomas, predominantly of the optic pathways. Moreover, foci of prolonged T2 relaxation were frequently observed, primarily in the globus pallidus of the basal ganglia and in the dentate nucleus of the cerebellum. Some of the foci in the globi pallidi exhibited increased signal intensity on T1-weighted images as well. NF-2 patients more frequently presented with bilateral acoustic schwannomas, meningiomas and cerebral white matter foci of prolonged T2 relaxation, but they did not have dentate and basal ganglia lesions. The authors conclude thatganglia lesions. The authors conclude that as a rule the manifestations of NF-1 and NF-2 on cranial MRI are separate and distinct; they do not overlap. MRI is an useful clinical tool for the diagnosis and the follow-up of patients with neurofibromatosis

258

Cyclic sciatica caused by infiltrative endometriosis: MRI findings  

International Nuclear Information System (INIS)

Endometriosis, an important gynecological disorder of reproductive women, affects most commonly the ovaries and less frequently the gastrointestinal tract, chest, urinary tract, and soft tissues. Endometriosis classically appears on MRI as a mass with a large cystic component and variable signal intensities on T1- and T2-weighted images due to the presence of variable degradation of hemorrhagic products. Endometriosis in an atypical location, an infiltrative appearance and without cystic-hemorrhagic components has rarely been described. We report on a 33-year-old woman with cyclic sciatica due to histologically documented infiltrative endometriosis involving the area of the left sciatic notch. (orig.)

259

Brain CT and MRI findings after carbon monoxide toxicity.  

Science.gov (United States)

The neuropathologic sequelae of carbon monoxide (CO) toxicity have been well described in postmortem examinations. Globus pallidus damage as well as diffuse white matter lesions and encephalopathic changes occur. Brain CT has provided imaging correlates to the premortem changes. MRI is more sensitive and provides more specificity. Cerebral edema changes may occur early with subsequent demonstration of globus pallidus lesions and white matter changes. Globus pallidus lesions in many cases do not correlate directly to clinical status and outcome; however, the presence of diffuse white matter disease is a more reliable index of both. These changes are seen in patients in both accidental exposures to CO and in suicide attempts. PMID:10436761

Prockop, L D; Naidu, K A

1999-07-01

260

MRI Findings of Primary CNS Lymphoma in 26 Immunocompetent Patients  

International Nuclear Information System (INIS)

To record the MR imaging features of primary central nervous system lymphoma (PCNSL) and compare these features in monofocal and multifocal disease. Twenty-one cases of monofocal disease were compared to five cases of multifocal disease. All patients were examined by nonenhanced and contrast-enhanced MRI. Tumor location, tumor size, signal intensity, enhancement characteristics, age distribution, peritumoral edema, cystic changes, and the presence of calcifications were assessed. The MRI features were compared between the monofocal and multifocal disease cases. The 26 cases, including both the monofocal and multifocal cases, exhibited 37 lesions. Contrast-enhanced images showed variable enhancement patterns: homogeneous enhancement (33 lesions), ring-like enhancement (2), and 'open-ring-like' enhancement (2). The 'notch sign' was noted in four of 33 homogeneously enhancing lesions. One case of hemorrhage and three cases of cystic formation were observed. Intra-tumoral calcification was not found. The frontal lobe, the corpus callosum and the basal ganglia were commonly affected in both the monofocal and multifocal groups. Tumor size differed significantly between the two groups (t = 3.129, p 0.05) and the signal characteristics (p > 0.05) between the two groups. Our data show that PCNSL has a vo groups. Our data show that PCNSL has a variable enhancement pattern on MR images. We first reported two lesions with an 'open-ring' enhancement as well as four cases with a 'notch sign'. Monofocal PCNSL cases typically have larger sized tumors with mild or moderate enhancement

261

Comparative studies of MRI and operative findings in rotator cuff tear.  

Directory of Open Access Journals (Sweden)

Full Text Available A prospective study was performed to determine the accuracy of magnetic resonance imaging (MRI compared with operative findings in the evaluation of patients associated with rotator cuff tears. Fifty-four of 60 shoulders (58 patients examined by MRI were confirmed as full-thickness tears and 6 as partial-thickness tears at the time of surgery. The oblique coronal, oblique sagittal, and axial planes of T2-weighted images with the 0.5 tesla MRI system were obtained preoperatively and compared with operative findings. MRI correctly identified 46 of 54 full-thickness rotator cuff tears and 5 of 6 partial-thickness tears. A comparison of MRI and operative findings in full-thickness cuff tears showed a sensitivity of 85%, a specificity of 83%, and a positive prospective value (PPV of 99%. A comparison of partial-thickness tears showed a sensitivity of 83%, a specificity of 85%, and PPV of 39%. Linear regression analysis showed an excellent correlation between the MRI assessment and measurement at the time of surgery (r = 0.90, P < 0.01. MRI was useful in evaluating large and medium-sized rotator cuff tears, but less useful in distinguishing small full-thickness tears from partial-thickness tears.

Yamakawa S

2001-10-01

262

Comparative studies of MRI and operative findings in rotator cuff tear  

International Nuclear Information System (INIS)

A prospective study was performed to determine the accuracy of magnetic resonance imaging (MRI) compared with operative findings in the evaluation of patients associated with rotator cuff tears. Fifty-four of 60 shoulders (58 patients) examined by MRI were confirmed as full-thickness tears and 6 as partial-thickness tears at the time of surgery. The oblique coronal, oblique sagittal, and axial planes of T2-weighted images with the 0.5 tesla MRI system were obtained preoperatively and compared with operative findings. MRI correctly identified 46 of 54 full-thickness rotator cuff tears and 5 of 6 partial-thickness tears. A comparison of MRI and operative findings in full-thickness cuff tears showed a sensitivity of 85%, a specificity of 83%, and a positive prospective value (PPV) of 99%. A comparison of partial-thickness tears showed a sensitivity of 83%, a specificity of 85%, and PPV of 39%. Linear regression analysis showed an excellent correlation between the MRI assessment and measurement at the time of surgery (r=0.90, P<0.01). MRI was useful in evaluating large and medium-sized rotator cuff tears, but less useful in distinguishing small full-thickness tears from partial-thickness tears. (author)

263

MRI in the acute phase of spiral cord traumatic lesions: relationship between MRI findings and neurological outcome  

International Nuclear Information System (INIS)

Purpose. To evaluate the role of emergency MRI in the diagnosis of acute spinal injuries, and to correlate the MRI pattern with the neurological outcome. Materials and methods. Thirty-eight patients with MRI-proven spinal cord injury were classified according to the Frankel classification. MRI was always performed within 8 hours from trauma. Frankel classification divides spinal cord injuries into 5 classes of decreasing severity based on the presence of motor and/or sensory function loss. On the basis of the MRI findings the patients were classified in 3 groups: group 1 (intramedullary haematoma), group 2 (multi-meta-mer oedema), group 3 (single-metamer oedema). All patients underwent neurosurgery and were clinically evaluated until the stabilization of neurological recovery. Mean follow-up lime was 12 months. The MR images were retrospectively evaluated and correlated to the neurological outcome. Results. Twenty eight patients showed complete motor loss (Frankel classes A and B); of these 28 patients 12 (42.8%) had MRI evidence of intramedullary haematoma, 12 (42.8%) had multi-metamer oedema and 4 (14.4%) had single-meta-mer oedema. Of the 10 patients with incomplete motor loss, none had MRI evidence of haemorrhage, 4 (40%) showed multi-metamer oedema and 6 (60%) showed single-meta-mer oedema. Follow-up clinical assessment revealed that 14/38 patients (36,8%) had clinical improvement and 2/38 cases (5%) had a complete motor recovery, as demonstrated by the move to arecovery, as demonstrated by the move to a higher Frankel class. Conclusions. Our results, consistent with previous reports, confirm a strong correlation between the MRI appearance of traumatic spinal cord injuries in acute phase and long-term recovery of motor and sensory function: patients with initial haemorrhage had a poor prognosis, whereas those with spinal cord oedema had a good clinical outcome, as demonstrated by the passage to a higher Frankel class. MRI is particularly important in the initial evaluation of unconscious patients who cannot undergo a motor and sensory neurological evaluation, and to define the prognosis, which will influence the correct therapeutic choice

264

Whole-heart cine MRI in a single breath-hold. A compressed sensing accelerated 3D acquisition technique for assessment of cardiac function  

International Nuclear Information System (INIS)

Purpose: The aim of this study was to perform functional MR imaging of the whole heart in a single breath-hold using an undersampled 3 D trajectory for data acquisition in combination with compressed sensing for image reconstruction. Materials and Methods: Measurements were performed using an SSFP sequence on a 3 T whole-body system equipped with a 32-channel body array coil. A 3 D radial stack-of-stars sampling scheme was utilized enabling efficient undersampling of the k-space and thereby accelerating data acquisition. Compressed sensing was applied for the reconstruction of the missing data. A validation study was performed based on a fully sampled dataset acquired by standard Cartesian cine imaging of 2 D slices on a healthy volunteer. The results were investigated with regard to systematic errors and resolution losses possibly introduced by the developed reconstruction. Subsequently, the proposed technique was applied for in-vivo functional cardiac imaging of the whole heart in a single breath-hold of 27 s. The developed technique was tested on three healthy volunteers to examine its reproducibility. Results: By means of the results of the simulation (temporal resolution: 47 ms, spatial resolution: 1.4 x 1.4 x 8 mm, 3 D image matrix: 208 x 208 x 10), an overall acceleration factor of 10 has been found where the compressed sensing reconstructed image series shows only very low systematic errors and a slight in-plane resolution loss of 15 %. The results of the in-vivo study (temporal resolution: 40.5 ms, spatial resolution: 2.1 x 2.1 x 8 mm, 3 D image matrix: 224 x 224 x 12) performed with an acceleration factor of 10.7 confirm the overall good image quality of the presented technique for undersampled acquisitions. Conclusion: The combination of 3 D radial data acquisition and model-based compressed sensing reconstruction allows high acceleration factors enabling cardiac functional imaging of the whole heart within only one breath-hold. The image quality in the simulated dataset and the in-vivo measurement highlights the great potential of the presented technique for an efficient assessment of cardiac functional parameters. (orig.)

265

Whole-heart cine MRI in a single breath-hold. A compressed sensing accelerated 3D acquisition technique for assessment of cardiac function  

Energy Technology Data Exchange (ETDEWEB)

Purpose: The aim of this study was to perform functional MR imaging of the whole heart in a single breath-hold using an undersampled 3 D trajectory for data acquisition in combination with compressed sensing for image reconstruction. Materials and Methods: Measurements were performed using an SSFP sequence on a 3 T whole-body system equipped with a 32-channel body array coil. A 3 D radial stack-of-stars sampling scheme was utilized enabling efficient undersampling of the k-space and thereby accelerating data acquisition. Compressed sensing was applied for the reconstruction of the missing data. A validation study was performed based on a fully sampled dataset acquired by standard Cartesian cine imaging of 2 D slices on a healthy volunteer. The results were investigated with regard to systematic errors and resolution losses possibly introduced by the developed reconstruction. Subsequently, the proposed technique was applied for in-vivo functional cardiac imaging of the whole heart in a single breath-hold of 27 s. The developed technique was tested on three healthy volunteers to examine its reproducibility. Results: By means of the results of the simulation (temporal resolution: 47 ms, spatial resolution: 1.4 x 1.4 x 8 mm, 3 D image matrix: 208 x 208 x 10), an overall acceleration factor of 10 has been found where the compressed sensing reconstructed image series shows only very low systematic errors and a slight in-plane resolution loss of 15 %. The results of the in-vivo study (temporal resolution: 40.5 ms, spatial resolution: 2.1 x 2.1 x 8 mm, 3 D image matrix: 224 x 224 x 12) performed with an acceleration factor of 10.7 confirm the overall good image quality of the presented technique for undersampled acquisitions. Conclusion: The combination of 3 D radial data acquisition and model-based compressed sensing reconstruction allows high acceleration factors enabling cardiac functional imaging of the whole heart within only one breath-hold. The image quality in the simulated dataset and the in-vivo measurement highlights the great potential of the presented technique for an efficient assessment of cardiac functional parameters. (orig.)

Wech, T.; Koestler, H. [Wuerzburg Univ. (Germany). Inst. of Radiology; Wuerzburg Univ. (Germany). Comprehensive Heart Failure Center; Pickl, W.; Tran-Gia, J.; Ritter, C.; Hahn, D. [Wuerzburg Univ. (Germany). Inst. of Radiology; Beer, M. [Wuerzburg Univ. (Germany). Inst. of Radiology; Graz Univ. (Austria). University Hospital Radiology

2014-01-15

266

The clinical characteristics and MRI findings of acquired hepatocerebral degeneration  

Directory of Open Access Journals (Sweden)

Full Text Available Acquired hepatocerebral degeneration (AHD is a rare chronic encephalopathy, and its etiology is usually correlated with cirrhosis and portal hypertension. In this study, clinical and radiological data of 326 patients with cirrhosis of the liver were retrospectively analyzed, among whom 11 patients were diagnosed as AHD, with the incidence of 3.37% . The most common neurological symptoms were static tremor (9 cases and ataxia (7 cases. Cerebral MRI showed T1WI hyperintensity in bilateral globus pallidus of all 11 patients. The lesions were also involved in bilateral thalamus (one case, tegment of midbrain (one case, bilateral posterior crus of internal capsule (one case and bilateral putamen (one case. Anti-Parkinson's disease drugs, such as levodopa and benserazide, had not presented satisfactory clinical effect. DOI: 10.3969/j.issn.1672-6731.2015.02.014

Xiao-yu DONG

2015-03-01

267

MRI Findings of Primary CNS Lymphoma in 26 Immunocompetent Patients  

Energy Technology Data Exchange (ETDEWEB)

To record the MR imaging features of primary central nervous system lymphoma (PCNSL) and compare these features in monofocal and multifocal disease. Twenty-one cases of monofocal disease were compared to five cases of multifocal disease. All patients were examined by nonenhanced and contrast-enhanced MRI. Tumor location, tumor size, signal intensity, enhancement characteristics, age distribution, peritumoral edema, cystic changes, and the presence of calcifications were assessed. The MRI features were compared between the monofocal and multifocal disease cases. The 26 cases, including both the monofocal and multifocal cases, exhibited 37 lesions. Contrast-enhanced images showed variable enhancement patterns: homogeneous enhancement (33 lesions), ring-like enhancement (2), and 'open-ring-like' enhancement (2). The 'notch sign' was noted in four of 33 homogeneously enhancing lesions. One case of hemorrhage and three cases of cystic formation were observed. Intra-tumoral calcification was not found. The frontal lobe, the corpus callosum and the basal ganglia were commonly affected in both the monofocal and multifocal groups. Tumor size differed significantly between the two groups (t = 3.129, p < 0.01) and mildly or moderately enhanced lesions were more frequently found in the monofocal group (p < 0.05). There was no statistical difference between perifocal edema (p > 0.05) and the signal characteristics (p > 0.05) between the two groups. Our data show that PCNSL has a variable enhancement pattern on MR images. We first reported two lesions with an 'open-ring' enhancement as well as four cases with a 'notch sign'. Monofocal PCNSL cases typically have larger sized tumors with mild or moderate enhancement

Zhang, Dong; Wang, Wen Xian; Wen, Li; Zou, Li Guang [XinQiao Hospital, Third Military Medical University, ChongQing (China); Hu, Liang Bo [The Second People' s Hospital of ChongQing, ChongQing (Korea, Republic of); Henning, Tobias D.; Ravarani, Elisabeth M. [Technical University Munich, Munich (Germany); Feng, Xiao Yuan [HuaShan Hospital, Medical Center of FuDan University, ShangHai (China)

2010-06-15

268

MRI findings in Tolosa-Hunt syndrome before and after systemic corticosteroid therapy  

Energy Technology Data Exchange (ETDEWEB)

Tolosa-Hunt syndrome (THS) is characterized by painful ophthalmoplegia due to a granulomatous inflammation in the cavernous sinus. Corticosteroid therapy dramatically resolves both the clinical and radiological findings of THS. We present MRI findings of six patients with a clinical history of at least one episode of unilateral or bilateral orbital-periorbital pain, clinical findings of associated paresis of one or more of 3rd, 4th, 5th or 6th cranial nerves. All of the patients revealed an enlargement of the symptomatic cavernous sinus on magnetic resonance imaging (MRI) scans. Five patients revealed total resolution of the clinical findings within 1-8 weeks, following systemic corticosteroid treatment. One patient revealed only minor regression of clinical findings within 2 weeks after the initiation of the treatment, so the cavernous sinus lesion was reevaluated as meningioma on MRI, and the patient underwent surgical resection of the mass with resultant histopathological finding of cavernous sinus meningioma. A follow-up MRI scan was performed for five patients at the end of 8-weeks of steroid therapy. Three of these five patients showed total resolution of the cavernous sinus lesions whereas two of them revealed a partial regression of the cavernous sinus lesions. MRI findings before and after systemic corticosteroid therapy are important diagnostic criteria to put the definitive diagnosis of THS and to differentiate it from other cavernous sinus lesions that simulate THS both clinically and radiologically.

Cakirer, Sinan E-mail: scakirer@yahoo.com

2003-02-01

269

Novel MRI finding for diagnosis of invasive placenta praevia: evaluation of findings for 65 patients using clinical and histopathological correlations  

Energy Technology Data Exchange (ETDEWEB)

To review established magnetic resonance (MR) criteria and describe a new MR finding for the diagnosis of invasive placenta praevia. A retrospective review of prenatal MRI examinations of 65 patients (median age: 35 years) who underwent MR for the screening of invasive placenta praevia. All MRIs were performed on a 1.5-T unit, including axial, coronal and sagittal T2-weighted half-Fourier single-shot turbo spin echo imaging. Fifteen patients were diagnosed with invasive placenta praevia. Two experienced radiologists reviewed the MR images and evaluated a total of six MRI features of the placenta, including our novel finding of the placental protrusion into the internal os (placental protrusion sign). Inter-rater reliability was assessed by using kappa statistics. Features with a kappa statistic >0.40 were evaluated using Fisher's two-sided exact test for comparison of their capabilities for placental invasion assessment. Interobserver reliability was moderate or better for the intraplacental T2 dark band, intraplacental abnormal vascularity, uterine bulging, heterogeneous placenta and placental protrusion sign. Fisher's two-sided exact test results showed all these features were significantly associated with invasive placenta praevia. The novel MRI finding of a placental protrusion sign is a useful addition to the established MRI findings for the diagnosis of invasive placenta praevia. (orig.)

Ueno, Yoshiko; Kitajima, Kazuhiro; Maeda, Tetsuo; Suenaga, Yuko; Takahashi, Satoru; Sugimura, Kazuro [Kobe University Graduate School of Medicine, Department of Radiology, Kobe (Japan); Kawakami, Fumi [Kobe University Graduate School of Medicine, Department of Pathology, Kobe (Japan); Matsuoka, Shozo; Tanimura, Kenji; Yamada, Hideto [Kobe University Graduate School of Medicine, Department of Obstetrics and Gynaecology, Kobe (Japan); Ohno, Yoshiharu [Kobe University Graduate School of Medicine, Department of Radiology, Kobe (Japan); Kobe University Graduate School of Medicine, Advanced Biomedical Imaging Research, Kobe (Japan)

2014-04-15

270

A case of hippocampal sclerosis diagnosed as cortical dysplasia due to preoperative brain MRI finding  

Directory of Open Access Journals (Sweden)

Full Text Available Hippocampal sclerosis (HS is one of the most common features of intractable temporal lobe epilepsy. Generally it can be identified through brain magnetic resonance imaging (MRI with high degree of sensitivity and specificity. Typical brain MRI findings of HS are hippocampal atrophy with hyperintense signal confined to the lesion. On the other hand cortical dysplasia exhibits blurring of the gray-white matter junction and abnormal white matter signal intensity. We present a case where preoperative brain MRI strongly suggested the presence of diffuse cortical dysplasia in the left temporal lobe but postoperative pathology revealed the temporal lesion to be unremarkable except for hippocampal sclerosis.

Jun Seok Lee

2010-01-01

271

Evaluation of CT Scan and MRI Findings of Pathologically Proved Gliomas in an Iranian Population  

OpenAIRE

Purpose: The aim of this study was to report the main CT scan and MRI findings of gliomas in a group of Iranian patients. Material and Methods: The MRI and CT scan of 96 pathologically proven patients of gliomas were retrospectively evaluated in a period of five years in our university affiliated hospital. We included all cases who had both CT scan and MRI in our study. Results: Among our patients, 60 (62.5%) were male and 36 (37.5%) were female. The mean age of our patients was 41.8?...

Sanei Taheri M; Samadian M; Aghaei M; Jalali A; Shakiba M

2008-01-01

272

Comparative studies of MRI and operative findings in rotator cuff tear.  

OpenAIRE

A prospective study was performed to determine the accuracy of magnetic resonance imaging (MRI) compared with operative findings in the evaluation of patients associated with rotator cuff tears. Fifty-four of 60 shoulders (58 patients) examined by MRI were confirmed as full-thickness tears and 6 as partial-thickness tears at the time of surgery. The oblique coronal, oblique sagittal, and axial planes of T2-weighted images with the 0.5 tesla MRI system were obtained preoperatively and compared...

Yamakawa S; Hashizume H; Ichikawa N; Itadera E; Inoue H

2001-01-01

273

First report of MRI findings in a case of an autoamputated wandering calcified ovary  

Science.gov (United States)

An autoamputated wandering calcified ovary (AWCO) is an extremely rare cause of abdominal calcification in the pediatric population. We present the magnetic resonance imaging (MRI) features of AWCO in a child. To our knowledge, the MRI features of AWCO have not been previously described in the published literature. Our case report indicates that the MRI findings are characteristic in the diagnosis of an AWCO and can completely obviate the need for invasive procedures in this mostly benign disease. An AWCO should be considered in all cases of mobile calcific opacities on radiographs in female patients. We advise that MRI be conducted in all suspected cases of AWCO for accurate and noninvasive diagnosis, and regular follow-up should be performed with ultrasound. The findings in our case report have the potential to change the course of investigations and management in suspected cases. PMID:24669196

Mahajan, Parag Suresh; Ahamad, Nazeer; Hussain, Sheik Akbar

2014-01-01

274

Characteristic MRI findings in beta-propeller protein-associated neurodegeneration (BPAN)  

OpenAIRE

A 31-year-old woman presented with severe dystonia-parkinsonism. She had nonprogressive psychomotor retardation and cognitive dysfunction from childhood without evidence of dystonia or parkinsonism. At age 30, she then developed severe dystonia and gait disturbance. There was neither dystonia nor parkinsonism before age 30. MRI revealed cerebral atrophy and iron accumulation in the globus pallidus and substantia nigra (figure 1, A–D). The characteristic MRI findings were hyperintensity of t...

Ichinose, Yuta; Miwa, Michiaki; Onohara, Akiko; Obi, Kimiko; Shindo, Kazumasa; Saitsu, Hirotomo; Matsumoto, Naomichi; Takiyama, Yoshihisa

2014-01-01

275

MRI findings and clinical outcome in 45 divers with spinal cord decompression sickness.  

OpenAIRE

BACKGROUND: Decompression sickness (DCS) affecting the spinal cord is the most dangerous form of diving-related injury with potential sequelae. This study was conducted to evaluate the relationship between spinal cord lesions on MRI and clinical findings in divers with spinal DCS. METHODS: We studied 45 cases of DCS that were referred to our hyperbaric facility with clinical evidence of spinal involvement during the period 2002-2007. The study included only patients who underwent MRI within 1...

Gempp, Emmanuel; Blatteau, Jean-eric; Stephant, Eric; Pontier, Jean-michel; Constantin, Pascal; Pe?ny, Christophe

2008-01-01

276

Identifying biological pathways in the MRI findings of people with low back pain  

DEFF Research Database (Denmark)

Title Identifying biological pathways in the MRI findings of people with low back pain Authors and affiliations Rikke K Jensen1, Tue Secher Jensen1, Per Kjaer1,2, Peter Kent1 1Research Department, Spine Centre of Southern Denmark, Hospital Lillebaelt, Institute of Regional Health Services Research, University of Southern Denmark, Part of the Clinical Locomotion Network, Middelfart, Denmark. 2Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Part of the Clinical Locomotion Network, Odense, Denmark Contact email rikke.kruger.jensen@slb.regionsyddanmark.dk Background Investigations into the association between lumbar MRI findings and low back pain (LBP) are complicated by multiple MRI findings being present at the same time. Findings such as lumbar intervertebral disc protrusions or endplate changes almost always co-exist with other degenerative disc findings such as the reduction of disc height and signal intensity. Despite this, the majority of previous research has focused solely on the associations between single imaging findings and pain or other clinical outcomes. Only recently have researchers started to engage with this complexity of MRI findings. An initial strategy to advance this area of investigation would be to recognise which MRI findings typically occur together and whether those clusters appear to reflect discrete biological pathways. Therefore, the objectives of this proof-of-concept study were to identify which vertebral MRI findings cluster together and describe plausible biological pathways that these clusters might represent. Methods All participants were people with chronic LBP seeking a comprehensive evaluation at an outpatient spine clinic in a Danish university hospital. Data for this study was extracted from the MRI findings of 631 people (3,155 lumbar spine motion segments) whose images were quantitatively coded using a detailed research protocol as part of the recruitment phase of two clinical trials. Reproducibility is high when using this MRI coding protocol (kappa 0.52-0.97). The MRI variables included in this study were information on intervertebral disc height and signal intensity, disc protrusions, high intensity zones, size and type of vertebral endplate signal changes, vertebral endplate irregularities and defects, osteophytes, and spondylolisthesis. Latent class analysis (probabilistic data mining) was used to distinguish the best fitting clusters of MRI findings. The distribution of lumbar disc levels in each cluster was also reported. Based on known histological changes inherent in the degeneration process of the motion segment, the clusters were grouped into hypothetical biological pathways. Results Latent class analysis identified twelve clusters of MRI findings. One cluster, characterised by no abnormal MRI findings, contained 52% of the motion segments and represented the normal, pre-degenerative motion segments. The following hypothetical pathways were derived from the content of the other clusters: (i) two clusters representing progressive stages of disc degeneration in the lower lumbar levels; (ii) four clusters representing progressive stages of disc protrusions and endplate changes in the lower lumbar levels; (iii) two cluster with endplate changes at either the upper or the lower endplates; (iv) two clusters containing progressive endplate changes and disc degeneration at the upper lumbar levels only; and lastly, (v) one cluster containing osteophytes at the upper lumbar motion segments. Conclusions MRI findings of lumbar vertebral motion segments were grouped into twelve clusters and those clusters fitted into a model of five different biological pathways of degeneration. Future research will test the association between these clusters and clinically important characteristics such as pain and activity limitation.

Jensen, Rikke Krüger; Jensen, Tue Secher

277

CineGlob  

CERN Multimedia

CERN will be hosting the next CineGlobe International Film Festival from March 18 to 23 at the Globe of Science and Innovation with the theme “Beyond the Frontier”, This 4th edition will see 66 short films “inspired by science” in competition, including fiction films as well as documentaries. From Tuesday the 18th to Friday the 21st, special lunch sessions are organized from 12:30 to 13:30. Food will be available for purchase at the tent “Café Cinéma” next to the Globe. Special evenings While the short film screenings are the heart of the festival, every year CineGlobe also organizes compelling special events every night, from feature films to special musical performances: Tuesday 18th: The Swiss premiere of the acclaimed documentary film Particle Fever. Presented by BBC Storyville with Fabiola Gianotti and director Mark Levinson in attendance; Wednesday 19th: The result of the “Story Matter” Hacka...

CineGlob

2014-01-01

278

MRI findings of the brainstem of the neuro-Behcet syndrome  

Energy Technology Data Exchange (ETDEWEB)

We reported three cases of neuro-Behcet's syndrome which showed brainstem lesions on MRI compatible with the clinical symptoms. In Case 1, MRI showed a large, abnormal signal-intensity area in the pons and small, abnormal signal-intensity areas at the right cerebral peduncle, the bilateral basal ganglia, and the left thalamus. These lesions disappeared on MRI, in accordance with the remission of clinical symptoms. On the other hand, CT showed no positive findings. In Case 2, an abnormal signal-intensity area was disclosed at the left cerebral peduncle on MRI. This lesion was also identified on the CT scan. In Case 3, an abnormal signal-intensity area was present in the pons on MRI. In this case, CT showed no positive findings. In Cases 2 and 3, these lesions seemed to represent inflammatory or necrotic areas attributable to vasculitis;however, the extensive brainstem lesion seen on the MRI of Case 1 was a quite unique finding, for which no exact pathophysiological explanation is possible at the present time.

Fujiki, Naoto; Tashiro, Kunio; Yamada, Takayoshi; Ito, Kazunori; Honma, Sanae; Doi, Shizuki; Moriwaka, Fumio

1987-10-01

279

Ependymomas of the posterior cranial fossa: CT and MRI findings  

International Nuclear Information System (INIS)

We studied nine children with posterior cranial fossa ependymomas to identify specific neuroradiological features. Patients were studied preoperatively with CT and MRI; T1-, T2- and proton-density (PD)-weighted images were obtained. All children underwent surgery and a definite histopathological diagnosis was made. All the tumours grew into the fourth ventricle and caused dilatation of its upper part, which resembled a cap. All but one were separated from the vermis by a cleavage plane. In eight cases there was desmoplastic development through the foramina of the fourth ventricle, and five were heterogeneous due to necrosis and cystic change; one had a haemorrhagic area. In most cases the solid portion was isointense with grey matter on T1-weighted images, hyperintense on PD weighting, and isointense on T2-weighted images. On CT the tumour was isodense in six cases and calcification was detected in four. The presence of both desmoplastic development and a tumour/vermis cleavage plane in a posterior cranial fossa tumour isodense on CT is highly suggestive of ependymoma. (orig.)

280

Movimientos migratorios y cine  

Directory of Open Access Journals (Sweden)

Full Text Available Nuestro artículo se ha centrado en el estudio de las películas de mayor distribución comercial para ver cómo éstas han representado el tema de la migración y qué reflexiones sugieren. En general, creemos que el reconocimiento por parte del cine de este fenómeno es positivo y que indudablemente constituye una fuente esencial para comprender las realidades migratorias distinguiendo discursos diversos y explicitando intenciones y hechos que intentan ocultarse u olvidarse.

Manuel Galiano León

2008-02-01

281

MRI findings in posterior disc prolapse associated with cervical fracture dislocation  

Energy Technology Data Exchange (ETDEWEB)

Although disc injury is common in cervical spinal fractures the mechanism of disc herniation in cervical fracture dislocations is not known. This study evaluated the pathogenesis of disc hernia in cervical fracture dislocations. Twenty-two patients who underwent anterior and posterior spinal fixation were studied. Findings of preoperative magnetic resonance imaging (MRI) were compared with surgical findings. During surgery, cervical disk hernia were found in six patients (27 %), and the MRI finding of these patients were evaluated in detail. We concluded that the characteristic MRI findings of cervical disc hernia are as follows: (1) discontinuity of injured disc, (2) anterior indentation of spinal cord at the site of dislocated vertebral body, and (3) signal irregularity at the site of interspace between dislocated vertebral body and spinal cord. (author).

Maeda, Go; Shiba, Keiichiro; Ueta, Takayoshi; Shirasawa, Kenzo; Ohta, Hideki; Mori, Eiji; Rikimaru, Shunichi; Hida, Shinichi; Tokunaga, Masami (Spinal Injuries Center, Fukuoka (Japan))

1994-03-01

282

Abnormal findings of magnetic resonance imaging (MRI) in patients with systemic lupus erythematosus involving the brain  

International Nuclear Information System (INIS)

To elucidate the clinical significance of MRI on central nervous system systemic lupus erythematosus (CNS-SLE), MRI and CT scans were performed in 35 patients with SLE, of 18 patients who had CNS manifestations at the time of MRI examinations. The investigations were also carried out in 17 patients without CNS-SLE. The rate of detection of abnormal findings on MRI in patients with CNS-SLE was 77.2% (14/18), which was high, as compared with the rate of those on CT scans (50%: 9/18). Especially, all of 4 patients with seizure and 3 patients with encephalopathy showed abnormal MRI findings, although respectively 50% and 33.3% of them had abnormal CT scan findings. MRI findings were classified into 4 groups below: 1) Large focal are as increased signal intensity at T2 weighted image. These were observed in 2 of 4 patients with seizure and 1 of 3 patients with encephalopathy, which were completely resolved after treatment. 2) Patchy subcortical foci of increased signal intensity at T2 weighted image. These were observed in 11 of 18 CNS-SLE and 7 of 17 without CNS-SLE, which were not detected by CT scan. 3) All of six patients with cerebral infarctions showed high signal intensity areas at T2 weighted image and low signal intensity areas at T1 weighted image. 4) Normal findings were observed in 4 of 18 CNS-SLE (22.2%). We concluded that MRI is useful for the evaluation of CNS-SLE and provides more information than CT scan. (author)

283

MRI findings in the liver of biliary atresia patients. Changes in postoperative course  

International Nuclear Information System (INIS)

We studied the morphological changes in the liver in the postoperative course of biliary atresia (BA) patients by means of periodic MRI. Periodic MRI (every year) was done in 24 of 34 patients, who were operated on at our institute by hepatic portoenterostomy. For the 24 patients studied, we investigated the changes in liver morphology seen in the following MRI findings. Inflammation and fibrosis in the portal system areas: Fibrosis in the peripheral liver lobe: Atrophy of the liver lobe: Reconstructive change in the liver parenchyma. Three images, T1 weighted image (WI) with and without Gd-DTPA, and T2 WI, were taken in each examination. We also studied the correlation between the MRI findings and level of total bilirubin in serum. The results were as follows: The inflammation and fibrosis in the portal system areas were marked just after the operation, and then decreased during the 3-5 year postoperative period. The degree of other MRI findings gradually increased during the 3-5 year postoperative period. The degree of these MRI findings had not changed at the end of the 5th postoperative year. The extent of the MRI findings, except for that of peripheral liver atrophy, was correlated with the increase in the level of total bilirubin in serum. These results indicate that the inflammation and/or fibrosis either remained static or progressed in the liver of postoperative BA patients during the 3-5 year postoperative period, and that these changes in the liver become id that these changes in the liver become irreversible after the 5 year postoperative period. The morphological changes found in this study could reflect the pathogenesis in the liver of postoperative BA patients. (author)

284

Prenatal MRI Findings of Fetuses with Congenital High Airway Obstruction Sequence  

International Nuclear Information System (INIS)

To define the MRI findings of congenital high airway obstruction sequence (CHAOS) in a series of fetuses. Prenatal fetal MR images were reviewed in seven fetuses with CHAOS at 21 to 27 weeks of gestation. The MRI findings were reviewed. The MRI parameters evaluated included the appearance of the lungs and diaphragm, presence or absence of hydrops, amount of amniotic fluid, airway appearance, predicted level of airway obstruction, and any additional findings or suspected genetic syndromes. All the fetuses viewed (7 of 7) demonstrated the following MRI findings: dilated airway below the level of obstruction, increased lung signal, markedly increased lung volumes with flattened or inverted hemidiaphragms, massive ascites, centrally positioned and compressed heart, as well as placentomegaly. Other frequent findings were anasarca (6 of 7) and polyhydramnios (3 of 7). MRI identified the level of obstruction as laryngeal in five cases and tracheal in two cases. In four of the patients, surgery or autopsy confirmed the MRI predicted level of obstruction. Associated abnormalities were found in 4 of 7 (genetic syndromes in 2). Postnatal radiography (n = 3) showed markedly hyperinflated lungs with inverted or flattened hemidiaphragms, strandy perihilar opacities, pneumothoraces and tracheotomy. Two fetuses were terminated and one fetus demised in utero. Four fetuses were delivered via ex utero intrapartum treatment procedure. MRI shows a consistent pattern of abnormalities in fe consistent pattern of abnormalities in fetuses with CHAOS, accurately identifies the level of airway obstruction, and helps differentiate from other lung abnormalities such as bilateral congenital pulmonary airway malformation by demonstrating an abnormally dilated airway distal to the obstruction

285

Abnormal findings of magnetic resonance imaging (MRI) in patients with systemic lupus erythematosus involving the brain  

Energy Technology Data Exchange (ETDEWEB)

To elucidate the clinical significance of MRI on central nervous system systemic lupus erythematosus (CNS-SLE), MRI and CT scans were performed in 35 patients with SLE, of 18 patients who had CNS manifestations at the time of MRI examinations. The investigations were also carried out in 17 patients without CNS-SLE. The rate of detection of abnormal findings on MRI in patients with CNS-SLE was 77.2% (14/18), which was high, as compared with the rate of those on CT scans (50%: 9/18). Especially, all of 4 patients with seizure and 3 patients with encephalopathy showed abnormal MRI findings, although respectively 50% and 33.3% of them had abnormal CT scan findings. MRI findings were classified into 4 groups below: (1) Large focal are as increased signal intensity at T2 weighted image. These were observed in 2 of 4 patients with seizure and 1 of 3 patients with encephalopathy, which were completely resolved after treatment. (2) Patchy subcortical foci of increased signal intensity at T2 weighted image. These were observed in 11 of 18 CNS-SLE and 7 of 17 without CNS-SLE, which were not detected by CT scan. (3) All of six patients with cerebral infarctions showed high signal intensity areas at T2 weighted image and low signal intensity areas at T1 weighted image. (4) Normal findings were observed in 4 of 18 CNS-SLE (22.2%). We concluded that MRI is useful for the evaluation of CNS-SLE and provides more information than CT scan. (author).

Ishikawa, Akira; Okada, Jun; Kondo, Hirobumi (Kitasato Univ., Sagamihara, Kanagawa (Japan). School of Medicine); Kashiwazaki, Sadao

1992-06-01

286

Prevalence and type of incidental extramammary findings in MRI of the breast  

International Nuclear Information System (INIS)

Purpose: To analyze prevalence and type of relevant incidental findings in patients undergoing breast MRI. Materials and Methods: This prospective investigation consists of 1013 patients who underwent breast MRI as follow-up after breast cancer therapy, for pre-operative staging, and for screening of high-risk patients as well as for clarification of unclear clinical examinations and inconclusive conventional mammography. Prevalence and type of relevant incidental extramammary findings were recorded together with the indication of the examination. Results: Incidental extramammary findings were encountered in 92 (9%) of the 1013 patients. MRI had markedly more incidental extramammary findings with the staging examinations (39.5%) and follow-up examinations (11.6%). The prevalence of incidental malignant findings was 81% in patients examined for pre-operative staging. Incidental benign and malignant findings were equally frequent in patients followed after breast cancer therapy. The incidental findings were exclusively benign in patients without a history of breast cancer. Conclusion: The interpretation of breast MRI should incorporate a careful analysis of the adjacent extramammary structures. Especially patients followed after breast cancer therapy can be expected to have incidental malignant findings outside the breast. (orig.)

287

CT and MRI findings and classification study of brain schistosomiasis granuloma  

International Nuclear Information System (INIS)

Objective: To study CT and MRI features and classification of brain schistosomiasis granuloma. Methods: CT and MRI data of 30 cases of brain schistosomiasis granuloma were reviewed. All cases were proved by the surgery or pathological examination and clinical laboratory test. There were 20 males and 10 females, and their age ranged from 5 to 58 years, mean 29.2 years. Plain and enhanced CT were performed in all patients with GE MAX 640 scanner. Ten patients were examined by plain and enhanced MRI with GE Signa profile 0.2 Tesla open scanner. Results: The lesions located in supratentorial region in 27 cases and in infratentorial region in 3 cases. The nodules were isodense or slight hyperdense on CT plain scan, iso or hypointense on T1WI, hyperintense on T2WI, Slight hyperintense on FLAIR. After the contrast material was injected intravenously, CT and MRI findings were multiple or single enhanced nodules at the cortical or subcortical area. There were four types of imaging features: (1) multiple small nodules in 5 cases (presenting as bright stars in the dark sky); (2) single large nodule in 8 cases; (3) mixed nodules in 14 cases; (4) circle-enhanced nodules in 3 cases. Conclusion: The brain schistosomiasis granuloma has typical CT and MRI findings. CT and MRI classification is not only helpful to its diagnosis and differential diagnosis, but also might be useful for the choice of clinical treatment

288

MRI findings in an infant with vaccine-associated paralytic poliomyelitis  

Energy Technology Data Exchange (ETDEWEB)

Although acute flaccid paralysis is a manifestation observed in several neurologic and muscular disorders, vaccine-associated paralytic poliomyelitis (VAPP) is an exceedingly rare etiology. In the clinical setting of acute flaccid paralysis, MRI is useful in differentiating between VAPP and other conditions. Additionally, MRI can assess the extent of lesions. However, reports on MRI findings in VAPP are scarce in the pediatric radiology literature. We report a Brazilian infant who developed VAPP 40 days after receiving the first dose of oral polio vaccine (OPV). MR images of the cervical and thoracic spinal cord showed lesions involving the anterior horn cell, with increased signal intensity on T2-weighted sequences. We would like to emphasize the importance of considering VAPP as a differential diagnosis in patients with acute flaccid paralysis and an MRI showing involvement of medulla oblongata or spinal cord, particularly in countries where OPV is extensively administered. (orig.)

Lopes Ferraz-Filho, Jose Roberto [Sao Jose do Rio Preto Medical School, Department of Radiology, Hospital de Base, Sao Paulo, State (Brazil); Sao Jose do Rio Preto Medical School, Department of Radiology, Sao Jose do Rio Preto, Sao Paulo State (Brazil); Santos Torres, Ulysses dos; Portela de Oliveira, Eduardo; Soares Souza, Antonio [Sao Jose do Rio Preto Medical School, Department of Radiology, Hospital de Base, Sao Paulo, State (Brazil)

2010-12-15

289

Perianal disease in pediatric Crohn disease: a review of MRI findings  

Energy Technology Data Exchange (ETDEWEB)

Perianal complications of Crohn disease are a common occurrence in children and can result in significant morbidity when not accurately characterized prior to surgical intervention. MRI is an excellent imaging modality for the evaluation of perianal inflammatory bowel disease - allowing characterization and detailed description of perianal fistulas. MRI has many advantages over other imaging modalities for the pediatric patient. Radiologists will benefit from a sophisticated understanding of perianal anatomy, the classification of perianal fistulas, the advantages MRI offers in characterization of perianal fistulas as well as the common and incidental findings that are important in the MRI evaluation of perianal inflammatory bowel disease in children. Perianal fistulas are found at a high rate in pediatric referrals and are more commonly found in male patients. (orig.)

Compton, Gregory L.; Bartlett, Murray [Royal Children' s Hospital, Medical Imaging Department, Parkville, Victoria (Australia)

2014-10-15

290

MRI findings of radiation encephalopathy of brain stem after radiotherapy for nasopharyngeal cancer  

International Nuclear Information System (INIS)

Purpose: To study MRI findings and clinical manifestation of radiation encephalopathy (RE) of brain stem. Methods: MRI findings and clinical symptoms in 51 patients with RE of brain stem after radiotherapy for nasopharyngeal cancer were reviewed. Results: Clinical symptoms included number weakness or paralysis in the limbs and symptoms of damaged cranial nerves. All lesions appeared hypo- or iso-intense on spin echo(SE) T1-weighted images and inhomogeneous and mixed hyper- and iso-intense on Turbo spin echo (TSE) T2-weighted images. The lesions were located in mesencephalon, pons, medulla, basilar part of pons, basilar part of pons and medulla oblongata in 2,7,3,9 and 30 patients respectively. The enhancement patterns included irregular rings in 39 patients, spotty in 3 and no enhancement in 9 patients. Mass effect was minimal in all patients. On follow-up MRI, the lesions disappeared in 4 patients, did not change in size and shape in 8 patients and enlarged in 2 patients. Conclusion: MRI could demonstrate the characteristic findings of RE of brain stem. MRI findings sometimes are not consistent with the clinical symptoms

291

MRI findings and correlation with pathological features in breast phyllodes tumor  

International Nuclear Information System (INIS)

Objective: To study the MR Imaging features of breast phyllodes tumor (PT), and to correlate it with pathological results. Method: Clinical and MRI findings were retrospectively reviewed in twenty-seven women with 28 PTs lesions confirmed by surgical pathology. Statistical analyses were one-way ANOVA for size analysis, Fisher exact test for analysis of MR appearances and Spearman correlation to study the relationship between MRI findings and BI-RADS categories. Results: (1) The histologic findings were benign, borderline and malignant PTs in 14.3% (4/28), 53.6% (15/28) and 32.1% (9/28) of lesions, respectively. (2) The mean maximum-diameter were (6.4±3.9) cm, (5.7±2.2) cm in borderline type and (4.8±1.8) cm in benign type respectively. The results showed differences in lesion's size among the three type (F= 287.541, P=0.000), especially between malignant and benign type (P=0.033). (3) Internal non-enhanced septation and silt-like changes on enhanced images, as well as time-signal curve on MRI correlated significantly with the histological grade (P<0.05). (4) If the category BI-RADS ? 4a was considered to be a suspicious sign for malignant lesion, the diagnostic accuracy of MRI would be 96.4% (27/28), and the BI-RADS category of the MRI could reflect the PT's histological grade with a low correlation coefficient (r=0.382, P=0.045). Conclusion: The findings of PT on MRI have some characteristics, with tumor size and several MRI features correlating with the histological grade of breast PT. (authors)

292

CT and MRI findings in patients with suprasellar germ cell tumors  

International Nuclear Information System (INIS)

This is a retrospective analysis of CT and MRI findings in suprasellar germ cell tumors. The study population was comprised of 6 patients with germinomas, one with embryonal carcinoma, and one with mature teratoma. Suprasellar germinoma tended to have intratumoral low density on CT or intensity area on MRI, indicating tumor necrosis or occasionally cyst formation. Germinoma tissue may extend into the pituitary fossa. Sagittal MRI revealed that the extension was limited to the posterior part of the pituitary gland. MRI of the teratoma did not demonstrate extension of the tumor into the pituitary fossa. No germ cell tumor in this region was seen as calcification. Germinoma in this region did not always show marked homogeneous enhancement. These neuroradiological findings failed to determine subtypes of germ cell tumors. Two patients had germinomas in both the pineal and suprasellar areas. Two years after the total removal of pineal teratoma, it recurred in the suprasellar region that was not seen on the first MRI. In these two patients, germinomas called 'double midline tumors' seemed to have originated by CSF dissemination or subependymal seeding, which was not demonstrated on neuroradiological images. The teratoma case was thought to be one form of double midline tumor, because the first tumor tissue in the pineal region had been totally and extracapsulary removed two years earlier and the suprasellar lesion could not be demonstrated on sagittal MRI or CT scans. In costrated on sagittal MRI or CT scans. In conclusion, not only neuroradiological findings but also clinical findings such as tumor markers may be required in preoperative diagnosis of suprasellar germ cell tumors. (N.K.)

293

Monostotic fibrous dysplasia of the clivus: MRI and CT findings  

Energy Technology Data Exchange (ETDEWEB)

Fibrous dysplasia is a developmental disorder caused by abnormal proliferation and maturation of fibroblasts resulting in replacement of mature bone by structurally weak, immature woven bone. Clival involvement in monostotic fibrous dysplasia is extremely unusual, and has rarely been reported previously. We report a case of monostotic fibrous dysplasia of the clivus with special emphasis on the imaging findings and differential diagnosis. (orig.)

Sirvanci, M.; Karaman, K.; Onat, L.; Duran, C.; Ulusoy, O.L. [Department of Diagnostic Radiology, University of Kadir Has Medical School, Istanbul (Turkey)

2002-10-01

294

Monostotic fibrous dysplasia of the clivus: MRI and CT findings  

International Nuclear Information System (INIS)

Fibrous dysplasia is a developmental disorder caused by abnormal proliferation and maturation of fibroblasts resulting in replacement of mature bone by structurally weak, immature woven bone. Clival involvement in monostotic fibrous dysplasia is extremely unusual, and has rarely been reported previously. We report a case of monostotic fibrous dysplasia of the clivus with special emphasis on the imaging findings and differential diagnosis. (orig.)

295

Orígenes del cine científico médico  

Directory of Open Access Journals (Sweden)

Full Text Available El cine científico es desde sus orígenes un instrumento de investigación, docencia, comunicación y documentación. Sin embargo, en la mente de muchos de nuestros cineastas, tan sólo existe una idea vaga de que el cine nació de la ciencia. Se exponen algunas definiciones relacionadas con el tema, sus antecedentes y cómo ha influido en el campo de la medicina.

Eglis Esteban García Alcolea

2009-02-01

296

Incidental findings at MRI-enterography in patients with suspected or known Crohn’s disease  

Directory of Open Access Journals (Sweden)

Full Text Available AIM: To determine the frequency and clinical impact of incidental findings detected with magnetic resonance imaging (MRI-enterography in patients with suspected or known Crohn’s disease (CD.METHODS: Incidental findings were defined as unexpected lesions outside the small intestine, not previously known or suspected at the time of referral, and not related to inflammatory bowel disease. Through a systematic review of medical charts we analyzed the clinical impact of incidental findings, and compared the MRI findings with subsequent diagnostic procedures.RESULTS: A total of 283 patients were included in the analysis, and MRI detected active CD in 31%, fistula in 1.4% and abscess in 0.7%. Extra-intestinal findings not related to CD were recorded in 72 patients (25%, of which 58 patients (20% had 74 previously unknown lesions. Important or incompletely characterized findings were detected in 17 patients (6.0%. Incidental findings led to 12 further interventions in 9 patients (3.2% revealing previously unknown pathological conditions in 5 (1.8%. One patient (0.4% underwent surgery and one patient was diagnosed with a malignant disease. MRI detected incidental colonic lesions in 16 patients of which additional work-up in 4 revealed normal anatomy. Two patients (0.7% benefitted from the additional examinations, whereas incidental findings led to unnecessary examinations in 9 (3.2%.CONCLUSION: In a minority of patients with suspected or known CD, important incidental findings are diagnosed at MRI-enterography. However, a substantial number of patients experience unnecessary morbidity because of additional examinations of benign or normal conditions.

Michael Dam Jensen, Torben Nathan, Jens Kjeldsen, Søren Rafael Rafaelsen

2010-01-01

297

[Spinal extradural meningiomas: MRI findings in two cases].  

Science.gov (United States)

Spinal extradural meningiomas are rare and may be easily confused with malignant neoplasms. We report two unusual cases of epidural spinal meningioma one within the left C6-C7 foramen and the other within the left posterolateral epidural space at the T3-T4 level. Low signal intensity of the tumor on T2-wi, thickening and enhancement of the dura with only the possibility of bone erosion are the most characteristic MR findings. PMID:15356447

Vargas, M I; Abu Eid, M; Bogorin, A; Beltechi, R; Boyer, P; Javier, R M; Zöllner, G; Dietemann, J L

2004-06-01

298

Evaluation of MRI findings in non-specific inflammatory processes in the parasellar region  

International Nuclear Information System (INIS)

We report the MRI findings on 6 patients with a non-specific inflammatory process in the parasellar region. Ophthalmoplegia developed in all patients. Only two patients complained of boring pain behind the eye and one of mild headache. The other three patients did not complain of pain. MRI clearly showed the extent of the lesions. In two patients the lesion was localized in the cavernous sinus. In the other patients, the lesions extended to the orbital apex, intrasellar and suprasellar regions, infratemporal fossa, or other neighboring regions beyond the cavernous sinus. The signal intensity of the lesions on T2WI was variable. The lesions were significantly enhanced after administration of Gd-DTPA. They were non-homogeneously enhanced in some patients. In three patients the lesions were well enhanced on the initial MRI scans. However, they were less enhanced on subsequent follow-up MRI or CT. The signal intensity and the degree of enhancement may vary substantially during the evolution of the inflammatory process or by blood flow in the cavernous sinus. Painful ophthalmoplegia is encountered in diseases of diverse pathogenesis in which the signal intensity and the extent of the lesions are variable. The MRI findings in one patient were not different from those of perineural spread from extracranial lesions, especially the one in the nasopharynx. However, MRI showed no abnormality in the nasopharynx and the base of the skull. In this patient, the clinical sthe skull. In this patient, the clinical symptoms and MRI findings improved spontaneously. In some patients, the clinical symptoms and the extent of the pathological process were different from those in the classic Tolosa-Hunt syndrome. It could be suggested that the spectrum of non-specific inflammatory processes in the parasellar region is wider than the criteria for classic Tolosa-Hunt syndrome. (J.N.M.)

299

Differential diagnosis of truly suprasellar space-occupying masses: synopsis of clinical findings, CT, and MRI  

International Nuclear Information System (INIS)

This review demonstrates the features of truly suprasellar masses in modern imaging based on the clinical, CT, and MRI findings of 42 patients with suprasellar masses in correlation to the histologic findings. The radiologic examinations were evaluated retrospectively to determine if diagnosis can be made based on specific imaging patterns. The most frequent clinical findings of space-occupying suprasellar masses were visual disturbances, diabetes insipidus, and symptoms and signs of occlusive hydrocephalus. There were no clinical features specific for any of the observed masses. Craniopharyngiomas were the most frequent tumors. They appeared in two different forms, as cystic and as solid enhancing masses. The cystic tumors could not be differentiated from cystic hamartomas or cystic gliomas by CT or MRI. The solid craniopharyngiomas were similar to meningiomas and hamartomas. In craniopharyngiomas of adults calcifications were not common. In CT and especially in MRI gliomas were characterized by the diffuse infiltration of the adjacent brain tissue or optic nerve. Except for meningiomas, all lesions were highly variable in appearance, making a reliable characterization by CT and MRI difficult in many cases. However, administration of contrast media in some cases resulted in a better tumor delineation. Compared with unenhanced MRI the enhanced scans did not increase diagnostic efficacy for neoplasms, but were helpful in the differentiation from inflammatory diseases. fferentiation from inflammatory diseases. The MRI technique was superior to CT in demonstrating the anatomic relationships, thus facilitating evaluation of origin and extent of the lesions. The CT technique, of course, was more reliable in the detection of calcifications. Both CT and MRI are not tissue-specific, however, and suprasellar tumors as well as many other neoplasms cannot be classified using only one of these imaging techniques. (orig.)

300

Correlation between the outcome of extracorporeal shockwave therapy and pretreatment MRI findings for chronic plantar fasciitis.  

Science.gov (United States)

Background. The purpose of this study was to investigate the relationship between magnetic resonance imaging (MRI) findings before extracorporeal shockwave therapy (ESWT) and the treatment outcome of ESWT. Methods. This study examined 50 feet with chronic plantar fasciitis. The scores before ESWT and after a six-month follow-up were investigated using the Japanese Society for Surgery of the Foot (JSSF) Ankle-Hindfoot Scale and the Visual Analog Scale (VAS). MRI before ESWT was used for image evaluation. MRI revealed thickening of the plantar fascia (PF), and an investigation was conducted regarding the findings of a high-signal-intensity area (HSIA) inside the PF, edema near the PF, and bone marrow edema (BME) of the calcaneus. Results. The average JSSF score and VAS score improved significantly at follow-up. In total, 44 feet were noted in the improved group. MRI revealed that the average amounts of PF thickening did not significantly differ between the improved group and the non-improved group. HSIA, edema near the PF, and BME were observed in 36, 41, and 11 feet in the improved group, respectively; and 2, 4, and 2 feet in the non-improved group, respectively. Conclusions. An HSIA in the PF predicted symptom improvement more easily than other MRI findings. Level of Evidence: IV. PMID:25401230

Maki, Masahiro; Ikoma, Kazuya; Imai, Kan; Kido, Masamitsu; Hara, Yusuke; Arai, Yuji; Fujiwara, Hiroyoshi; Kubo, Toshikazu

2014-11-17

301

MRI findings at image guided adaptive cervix cancer brachytherapy: radiation oncologist's perspective.  

Science.gov (United States)

Magnetic resonance imaging (MRI) represents the reference imaging modality for image guided adaptive brachytherapy (IGABT) of cervix cancer. Accurate interpretation of pre-treatment MRI is required for proper understanding of the tumor extent and topography at IGABT. Planning and optimal timing of the application begins already before treatment, and may need to be adapted during external beam irradiation (EBRT) according to additional clinical and/or radiological findings. The level of MRI utilization in IGABT depends on the infrastructural capabilities of individual centers, ranging from no use at all to repetitive imaging during EBRT and each IGABT fraction. In this article, we summarize the role of different imaging modalities and practical aspects of MRI interpretation in cervix cancer IGABT, concentrating on the systematic evaluation of post-insertion images. MRI with the applicator in place from the radiation oncologist's perspective should begin with immediate identification of eventual complications of the application procedure and assessment of the implant adequacy, followed by appropriate corrective measures in case of adverse findings. Finally, the tumor extent, topography, and treatment response should be evaluated in the context of initial clinical and radiological findings to allow for an appropriate selection and delineation of the target volumes. PMID:25097564

Petric, Primoz; Mohammed-Al-Hammadi, Noora

2014-06-01

302

Unexpected MRI findings in clinically suspected Legg-Calve-Perthes disease  

International Nuclear Information System (INIS)

In the setting of clinically suspected Legg-Calve-Perthes (LCP) disease and negative/equivocal radiographs, contrast-enhanced MRI can be performed to confirm the diagnosis. To determine the frequency of unexpected causes of hip pain as identified by MRI in children with clinically suspected LCP disease and negative/equivocal radiographs. All pediatric contrast-enhanced MRI examinations of the pelvis and hips performed between January 2000 and February 2009 to evaluate for possible LCP disease in the setting of negative/equivocal radiographs were identified. MRI examinations performed to evaluate for secondary avascular necrosis were excluded. Imaging reports were retrospectively reviewed for unexpected clinically important causes of hip pain. Thirty-six pediatric patients underwent contrast-enhanced MRI examinations for clinically suspected LCP disease in the setting of negative/equivocal radiographs. Twenty-two (61%) imaging studies were normal, while four (11%) imaging studies demonstrated findings consistent with LCP disease. Ten (28%) imaging studies revealed unexpected clinically important causes of hip pain, including nonspecific unilateral joint effusion and synovitis (n = 7, juvenile chronic arthritis was eventually diagnosed in 3 patients), sacral fracture (n = 1), apophyseal injury (n = 1), and femoral head subluxation (n = 1). MRI frequently reveals unexpected clinically important causes of hip pain in children with suspected LCP disease and negative/equivo suspected LCP disease and negative/equivocal radiographs. (orig.)

303

Unexpected MRI findings in clinically suspected Legg-Calve-Perthes disease  

Energy Technology Data Exchange (ETDEWEB)

In the setting of clinically suspected Legg-Calve-Perthes (LCP) disease and negative/equivocal radiographs, contrast-enhanced MRI can be performed to confirm the diagnosis. To determine the frequency of unexpected causes of hip pain as identified by MRI in children with clinically suspected LCP disease and negative/equivocal radiographs. All pediatric contrast-enhanced MRI examinations of the pelvis and hips performed between January 2000 and February 2009 to evaluate for possible LCP disease in the setting of negative/equivocal radiographs were identified. MRI examinations performed to evaluate for secondary avascular necrosis were excluded. Imaging reports were retrospectively reviewed for unexpected clinically important causes of hip pain. Thirty-six pediatric patients underwent contrast-enhanced MRI examinations for clinically suspected LCP disease in the setting of negative/equivocal radiographs. Twenty-two (61%) imaging studies were normal, while four (11%) imaging studies demonstrated findings consistent with LCP disease. Ten (28%) imaging studies revealed unexpected clinically important causes of hip pain, including nonspecific unilateral joint effusion and synovitis (n = 7, juvenile chronic arthritis was eventually diagnosed in 3 patients), sacral fracture (n = 1), apophyseal injury (n = 1), and femoral head subluxation (n = 1). MRI frequently reveals unexpected clinically important causes of hip pain in children with suspected LCP disease and negative/equivocal radiographs. (orig.)

Lobert, Philip F.; Dillman, Jonathan R.; Strouse, Peter J.; Hernandez, Ramiro J. [University of Michigan Health System, Department of Radiology, Section of Pediatric Radiology, C.S. Mott Children' s Hospital/F3503, Ann Arbor, MI (United States)

2011-03-15

304

Neuroradiological findings in primary progressive aphasia: CT, MRI and cerebral perfusion SPECT  

International Nuclear Information System (INIS)

Primary progressive aphasia (PPA) is defined as progressive decline in language for 2 or more years with preservation of activities of daily living and general cognitive functions. Whereas the clinical features of this syndrome have been well documented, the neuroradiological findings have not been studied systematically. We studied 13 patients with PPA retrospectively: 10 underwent CT, 12 MRI and 12 cerebral perfusion studies using 99mTc-HMPAO SPECT. CT and MR images were scored for focal atrophy by two independent assessors. Initial qualitative assessment of SPECT images was confirmed by quantitative analysis. CY was normal in 5 patients. Focal atrophy, affecting predominantly the left temporal lobe, was seen in 4 of 10 patients on CT, and 10 of 12 on MRI. Atrophy was localised primarily to the superior and middle temporal gyri on MRI. All 12 patients who underwent SPECT had unilateral temporal lobe perfusion defects, in 2 patients of whom MRI was normal. CT is relatively insensitive to focal abnormalities in PPA; MRI and SPECT are the imaging modalities of choice. MRI allows accurate, specific localisation of atrophy with the temporal neocortex. SPECT may reveal a functional decrease in cerebral perfusion prior to establishment of structural change. (orig.)

305

Neuroradiological findings in primary progressive aphasia: CT, MRI and cerebral perfusion SPECT  

Energy Technology Data Exchange (ETDEWEB)

Primary progressive aphasia (PPA) is defined as progressive decline in language for 2 or more years with preservation of activities of daily living and general cognitive functions. Whereas the clinical features of this syndrome have been well documented, the neuroradiological findings have not been studied systematically. We studied 13 patients with PPA retrospectively: 10 underwent CT, 12 MRI and 12 cerebral perfusion studies using {sup 99m}Tc-HMPAO SPECT. CT and MR images were scored for focal atrophy by two independent assessors. Initial qualitative assessment of SPECT images was confirmed by quantitative analysis. CY was normal in 5 patients. Focal atrophy, affecting predominantly the left temporal lobe, was seen in 4 of 10 patients on CT, and 10 of 12 on MRI. Atrophy was localised primarily to the superior and middle temporal gyri on MRI. All 12 patients who underwent SPECT had unilateral temporal lobe perfusion defects, in 2 patients of whom MRI was normal. CT is relatively insensitive to focal abnormalities in PPA; MRI and SPECT are the imaging modalities of choice. MRI allows accurate, specific localisation of atrophy with the temporal neocortex. SPECT may reveal a functional decrease in cerebral perfusion prior to establishment of structural change. (orig.)

Sinnatamby, R. [Dept. of Radiology, Addenbrooke`s Hospital NHS Trust, Cambridge (United Kingdom); Antoun, N.A. [Dept. of Radiology, Addenbrooke`s Hospital NHS Trust, Cambridge (United Kingdom); Freer, C.E.L. [Dept. of Radiology, Addenbrooke`s Hospital NHS Trust, Cambridge (United Kingdom); Miles, K.A. [Dept. of Nuclear Medicine, Addenbrooke`s Hospital NHS Trust, Cambridge (United Kingdom); Hodges, J.R. [Dept. of Neurology, Addenbrooke`s Hospital NHS Trust, Cambridge (United Kingdom)

1996-04-01

306

MRI findings in patients with defecatory dysfunction after surgical correction of anorectal malformation  

International Nuclear Information System (INIS)

Postoperative anorectal malformation patients frequently have defecatory dysfunction. MRI may be useful in the management of these patients. To analyze static and dynamic MRI findings in patients with defecatory dysfunction after correction of anorectal malformation (ARM), and compare differences between patients with constipation and fecal incontinence. Pelvic MRI studies of 20 constipated and 32 incontinent postoperative ARM patients were analyzed retrospectively to determine the location and morphology of the neorectum, presence of peritoneal fat herniation, presence of scarring, development of the striated muscle complex (SMC) and any other abnormalities. The two groups were then compared using ? 2-test. Eighteen patients also underwent MRI defecography to evaluate pelvic floor function and abnormalities are reported. The children with incontinence were more likely to have abnormal location of the neorectum (P = 0.031), increased anorectal angle (ARA) (P = 0.031) and peritoneal fat herniation (P = 0.032), and less likely to have dilation of the neorectum (P = 0.027), than the children with constipation. There were no significant differences between the two groups in incidence of focal stenosis of the neorectum (P = 0.797), presence of extensive scarring (P = 0.591) and developmental agenesis of the SMC (P > 0.05). MRI defecography showed 6 anterior rectoceles, 6 cystoceles and 18 pelvic floor descents. MRI is a helpful imaging modality in postoperativehelpful imaging modality in postoperative ARM patients with defecatory dysfunction, and it shows distinct differences between the children with constipation and incontinence and provides individualized information to guide further treatment. (orig.)

307

MRI findings in patients with defecatory dysfunction after surgical correction of anorectal malformation  

Energy Technology Data Exchange (ETDEWEB)

Postoperative anorectal malformation patients frequently have defecatory dysfunction. MRI may be useful in the management of these patients. To analyze static and dynamic MRI findings in patients with defecatory dysfunction after correction of anorectal malformation (ARM), and compare differences between patients with constipation and fecal incontinence. Pelvic MRI studies of 20 constipated and 32 incontinent postoperative ARM patients were analyzed retrospectively to determine the location and morphology of the neorectum, presence of peritoneal fat herniation, presence of scarring, development of the striated muscle complex (SMC) and any other abnormalities. The two groups were then compared using {chi} {sup 2}-test. Eighteen patients also underwent MRI defecography to evaluate pelvic floor function and abnormalities are reported. The children with incontinence were more likely to have abnormal location of the neorectum (P = 0.031), increased anorectal angle (ARA) (P = 0.031) and peritoneal fat herniation (P = 0.032), and less likely to have dilation of the neorectum (P = 0.027), than the children with constipation. There were no significant differences between the two groups in incidence of focal stenosis of the neorectum (P = 0.797), presence of extensive scarring (P = 0.591) and developmental agenesis of the SMC (P > 0.05). MRI defecography showed 6 anterior rectoceles, 6 cystoceles and 18 pelvic floor descents. MRI is a helpful imaging modality in postoperative ARM patients with defecatory dysfunction, and it shows distinct differences between the children with constipation and incontinence and provides individualized information to guide further treatment. (orig.)

Cui, Yong; Shao, Guang-rui [Second Hospital of Shandong University, Department of Radiology, Jinan (China); Wang, Ruo-yi [Second Hospital of Shandong University, Department of Pediatric Surgery, Jinan (China); Zhang, Yuan [Second Hospital of Shandong University, Evidence-based Medical Center, Jinan (China); Zhang, Shu-hui [Second Hospital of Shandong University, Department of Laboratory, Jinan (China)

2013-08-15

308

Incidental findings at MRI-enterography in patients with suspected or known Crohn’s disease  

OpenAIRE

AIM: To determine the frequency and clinical impact of incidental findings detected with magnetic resonance imaging (MRI)-enterography in patients with suspected or known Crohn’s disease (CD).METHODS: Incidental findings were defined as unexpected lesions outside the small intestine, not previously known or suspected at the time of referral, and not related to inflammatory bowel disease. Through a systematic review of medical charts we analyzed the clinical impact of incidental findings, an...

Michael Dam Jensen, Torben Nathan

2010-01-01

309

Lumbar disc herniation at high levels : MRI and clinical findings  

International Nuclear Information System (INIS)

To assess the frequency, location, associated MR findings, and clinical symptoms of the high level lumbar disc herniation(HLDH). A total of 1076 patients with lunbar disc herniation were retrospectively reviewed. MR images of 41 of these with HLDH(T12-L1, L1-2, L2-3) were analysed in terms of frequency, location, and associated MR findings, and correlated with clinical symptoms of HLDH. The prevalence of HLDH was 3.8%(41/1076). HLDH was located at T12-L1 level in four patients(10%), at L1-2 level in 14(34%), at L2-3 level in 21(51%), and at both L1-2 and L2-3 levels in two. The age of patients ranged from 20 to 72 years (mean, 44), and there were 26 men and 16 women. In 11(27%), whose mean age was 32 years, isolated disc herniation was limited to these high lumbar segments. The remaining 30 patients had HLDH associated with variable involvement of the lower lumbar segments. Associated lesions were as follow : lower level disc herniation(14 patients, 34%); apophyseal ring fracture(8 patients, 19%); Schmorl's node and spondylolisthesis (each 6 patients, each 14%); spondylolysis(3 patients, 7%); and retrolisthesis(2 patients, 5%). In 20 patients(49%) with HLDH(n=41), there was a previous history of trauma. Patients with HLDH showed a relatively high incidence of associated coexisting abnormalities such as lower lumbar disc herniation, apophyseal ring fracture, Schmorl's node, spondylolysis, and retrolisthesis. In about half of all patients with HLDH there was a previous l patients with HLDH there was a previous history of trauma. The mean age of patients with isolated HLDH was lower; clinical symptoms of the condition were relatively nonspecific and their incidence was low

310

Lumbar disc herniation at high levels : MRI and clinical findings  

Energy Technology Data Exchange (ETDEWEB)

To assess the frequency, location, associated MR findings, and clinical symptoms of the high level lumbar disc herniation(HLDH). A total of 1076 patients with lunbar disc herniation were retrospectively reviewed. MR images of 41 of these with HLDH(T12-L1, L1-2, L2-3) were analysed in terms of frequency, location, and associated MR findings, and correlated with clinical symptoms of HLDH. The prevalence of HLDH was 3.8%(41/1076). HLDH was located at T12-L1 level in four patients(10%), at L1-2 level in 14(34%), at L2-3 level in 21(51%), and at both L1-2 and L2-3 levels in two. The age of patients ranged from 20 to 72 years (mean, 44), and there were 26 men and 16 women. In 11(27%), whose mean age was 32 years, isolated disc herniation was limited to these high lumbar segments. The remaining 30 patients had HLDH associated with variable involvement of the lower lumbar segments. Associated lesions were as follow : lower level disc herniation(14 patients, 34%); apophyseal ring fracture(8 patients, 19%); Schmorl's node and spondylolisthesis (each 6 patients, each 14%); spondylolysis(3 patients, 7%); and retrolisthesis(2 patients, 5%). In 20 patients(49%) with HLDH(n=41), there was a previous history of trauma. Patients with HLDH showed a relatively high incidence of associated coexisting abnormalities such as lower lumbar disc herniation, apophyseal ring fracture, Schmorl's node, spondylolysis, and retrolisthesis. In about half of all patients with HLDH there was a previous history of trauma. The mean age of patients with isolated HLDH was lower; clinical symptoms of the condition were relatively nonspecific and their incidence was low.

Paek, Chung Ho; Kwon, Soon Tae; Lee, Jun Kyu; Ahn, Jae Sung; Lee, Hwan Do; Chung, Yon Su; Jeong, Ki Ho; Cho, Jun Sik [Chungnam National Univ. College of Medicine, Taejon (Korea, Republic of)

1999-04-01

311

Evaluation of Agreement between CT scan and MRI Findings of 96 Pathologically Proved Gliomas  

Directory of Open Access Journals (Sweden)

Full Text Available Background/Objective: The aim of this study was to report the main CT scan and MRI findings of gliomas in a group of Iranian patients and also to assess the agreement between these imaging findings."nPatients and Methods: The MRI and CT scan of 96 pathologically proven cases of gliomas were retro-spectively evaluated in a period of five years in our university-affiliated hospital. We entered all cases, which had both CT scan and MRI in our study. Both CT scan and MRIs reported by one radiologist who was blinded for pathological findings. We evaluated agreement between CT scan and MRI for all cases and also for astrocytoma, glioblastoma multiform, and other gliomas separately. "nResults: Among our patients, 60 (62.5% were male and 36 (37.5% were female. The mean age of our cases was 41.8±19.3 (7-78.The most common loca-tion was in the parietal lobes (54.2% followed by the temporal lobes (52.1%, and the frontal lobes (39.6%. The most common subtype was glioblastoma multi-form in 42 patients (43.8%.There was an excellent agreement for mass effect, ventricular effect, cystic formation, and midline shift in all gliomas (all Kap-pas> 0.8; all P<0.002. We found good correlation be-tween CT scan and MRI for hemorrhage, edema, en-hancement, and enhancement severity in our pa-tients. (all Kappas> 0.6; all P<0.0001."nConclusion: In contrast with many other studies, the most common site of gliomas in our patients was pa-rietal lobes. Except for calcification, we found accept-able correlation between CT scan and MRI findings of gliomas.

M. Sanei Taheri

2008-01-01

312

MRI findings of intracranial lesions of neurofibromatosis type 1. Is routine study necessary for infants?  

International Nuclear Information System (INIS)

Neurofibromatosis type 1 (NF1) is the most common phakomatosis and is characterized by various intracranial disorders. Routine MRI studies are widely used to detect these disorders. To investigate the necessity of such routine MRI study of infants for NF1, we reviewed MRI findings of fifty-seven NF1 patients at the Kanagawa Children's Medical Center from January 1991 to October 1998. All patients were definitely diagnosed as NF1 because they clearly fulfilled the NIH criteria. We divided them into two groups, before 24 months of age (13 cases), and over 24 months of age (44 cases), because the myelination of the white matter should be terminated by then. We analyzed and compared the MRI findings of those two groups. Both mass-like and structural lesions including optic nerve astrocytoma, were mainly noticed in older group. Hamartomatous lesions, which are high intensity spots on T2WI mostly characteristic for NF1, were detected in 42 of a total of 57 patients (73.7%). They were mostly seen in the globus pallidus and cerebellar hemispheres. Hamartomas were seen 39 of 44 (88.6%) patients in the older group. This was significantly higher than in the younger group (30.8%). Follow-up MRI studies revealed newly appeared and differently sized hamartomas in both groups. MRI studies are very useful to detect intracranial lesion of NF1 patients. However we speculate that MRI studies are not very useful for infants under 24 months. It is more fruitful to wait at least 24 months more fruitful to wait at least 24 months until the maturation of the brain is normally completed. (author)

313

Hepatic Angiomyolipoma: Dual-Contrast MRI Findings Using Superparamagnetic Iron Oxide (SPIO) and Gadolinium Agents  

Energy Technology Data Exchange (ETDEWEB)

To analyze imaging findings of hepatic angiomyolipomas (AMLs) on dualcontrast MRI using superparamagnetic iron oxide (SPIO) and gadolinium (Gd) agents. Five histopathologically-proven hepatic AMLs were enrolled in this study. Patients underwent dual-contrast MRI using SPIO and Gd agents on a 3.0T unit and performed a qualitative analysis consisting of measuring the signal intensity (SI) of the lesion, presence of fat, hemorrhage, early draining vein, tortuous tumoral vessels, as well as capsule and enhancement patterns. The signal drop of the lesion on post-SPIO images was also assessed. For the quantitative analysis, relative signal decrease (RSD, %) was calculated. The presence of fat was noted in three lesions. An early draining vein and prominent tortous tumoral vessels were depicted in four lesions. No lesion was found to have a capsule. Four lesions showed early wash-in and early wash-out enhancement patterns, while the remaining lesion depicted strong and persistent enhancement. On post-SPIO images, signal drop was noted in the two lesions with no fat within the lesion. Their RSD was 21.1% and 38.0%, respectively. The presence of an early draining vein and tortuous tumoral vessels are characteristic dynamic enhanced MRI features of hepatic AMLs. In fat-deficient hepatic AMLs, the combination of dynamic enhanced MRI and SPIO-enhanced MRI might findings might increase the accuracy of making a correct diagnosis

Kim, Min Uk; Kim, Se Hyung; Kim, Hyo Cheol; Lee, Jae Young; Kim, Min A; Han, Joon Koo; Choi, Byung Ihn [Seoul National University Hospital College of Medicine, Seoul (Korea, Republic of)

2010-12-15

314

Localized hypertrophic neuropathy of the sciatic nerve in children: MRI findings  

Energy Technology Data Exchange (ETDEWEB)

Localized hypertrophic neuropathy (LHN) of the sciatic nerve in children is a rare condition characterized by a painless neurological deficit in the sciatic nerve territory. To demonstrate the role of MRI using a specific protocol and describe the primary findings in LHN. Imaging in four children (age 2 years to 12 years) is presented. All children presented with lower limb asymmetry. Three had a steppage gait. LHN was confirmed by electrophysiological studies and by MRI of the whole sciatic nerve with a dedicated protocol covering the lumbar spine and the lower limb. There were four direct MRI findings: (1) linear and focal hypertrophy with progressive enlargement of a peripheral nerve or plexus diameter, (2) abnormal hyperintensity of the nerve on T2-weighted images, (3) preserved fascicular configuration, and (4) variable enhancement after intravenous gadolinium administration. In addition there were atrophy and fatty infiltration of innervated muscles. MRI was helpful for determining the extent of lesions and in excluding peripheral nerve compression or tumour. MRI of the whole sciatic nerve is the method of choice for diagnosing LHN of the sciatic nerve. (orig.)

Roux, Adrien; Treguier, Catherine; Bruneau, Bertrand; Marin, Franck; Gandon, Yves; Gauvrit, Jean-Yves [University Hospital, Department of Radiology, Hopital Sud, 16 Boulevard de Bulgarie, BP 90347, Rennes cedex 2 (France); Riffaud, Laurent [University Hospital, Department of Pediatric Neurosurgery, Hopital Sud, Rennes (France); Violas, Philippe [University Hospital, Department of Pediatric Surgery, Hopital Sud, Rennes (France); Michel, Anne [University Hospital, Department of Neurological Functional Explorations, Hopital Sud, Rennes (France)

2012-08-15

315

Inflammatory myofibroblastic tumour of the maxillary sinus: CT and MRI findings  

International Nuclear Information System (INIS)

Aim: To characterize the computed tomography (CT) and magnetic resonance imaging (MRI) findings of inflammatory myofibroblastic tumours (IMTs) of the maxillary sinus. Materials and methods: The imaging findings of eight patients with IMTs of the maxillary sinus were reviewed retrospectively. Of the eight patients, four patients underwent unenhanced and contrast-enhanced CT, and one patient underwent unenhanced CT only; three patients underwent unenhanced and contrast-enhanced MRI. Results: Five cases of IMTs occurred in the left maxillary sinus, while three cases were right-sided. Four cases occupied the entire sinus, and the other four cases only partially occupied the sinus. Unenhanced CT images showed heterogeneous masses in four cases and a homogeneous mass in one case. One of the tumours showed some areas of calcification. T1-weighted MRI images showed isointense lesions. T2-weighted images showed mixed isointense and mild hyperintense lesions. All cases showed bone destruction and had infiltrated into the nasal fossa, orbit, infratemporal fossa, and other adjacent tissues. Seven cases showed mild to moderate heterogeneous enhancement on contrast-enhanced CT or T1-weighted MRI images. Conclusion: IMTs of the maxillary sinus can be characterized as a soft-tissue mass with bony destruction and infiltration of the adjacent tissues, with mild to moderate enhancement after the injection of contrast medium. CT and MRI can help to diagnose IMTs, determine the extent of to diagnose IMTs, determine the extent of the lesion and its relationship with adjacent tissues, and thus facilitate the prediction of surgical resectability.

316

Localized hypertrophic neuropathy of the sciatic nerve in children: MRI findings  

International Nuclear Information System (INIS)

Localized hypertrophic neuropathy (LHN) of the sciatic nerve in children is a rare condition characterized by a painless neurological deficit in the sciatic nerve territory. To demonstrate the role of MRI using a specific protocol and describe the primary findings in LHN. Imaging in four children (age 2 years to 12 years) is presented. All children presented with lower limb asymmetry. Three had a steppage gait. LHN was confirmed by electrophysiological studies and by MRI of the whole sciatic nerve with a dedicated protocol covering the lumbar spine and the lower limb. There were four direct MRI findings: (1) linear and focal hypertrophy with progressive enlargement of a peripheral nerve or plexus diameter, (2) abnormal hyperintensity of the nerve on T2-weighted images, (3) preserved fascicular configuration, and (4) variable enhancement after intravenous gadolinium administration. In addition there were atrophy and fatty infiltration of innervated muscles. MRI was helpful for determining the extent of lesions and in excluding peripheral nerve compression or tumour. MRI of the whole sciatic nerve is the method of choice for diagnosing LHN of the sciatic nerve. (orig.)

317

MRI findings of pancreatic lymphoma and autoimmune pancreatitis: A comparative study  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To clarify whether there are differences in MRI findings between pancreatic lymphomas and autoimmune pancreatitis (AIP). Materials and methods: MRI of 8 patients with pancreatic lymphomas and 21 patients with AIP were retrospectively reviewed. For multifocal pancreatic lymphomas (n = 2) and AIP (n = 4), the largest 2 lesions were evaluated. Ten pancreatic lymphomas and 25 AIP were compared on three bases: the signal intensity on T2-weighted images, internal homogeneity, and presence or absence of capsule-like rim. In 8 lymphomas and 19 AIP, the enhancement pattern on dynamic MRI was compared, as well. Results: On T2-weighted images, pancreatic lymphomas comprised 5, 5 and 4 lesions with low (iso), slightly high, and moderately high intensity, respectively, while the numbers for AIP were 14, 10, and 1 (P < 0.01). Nine of 10 (90%) lymphomas appeared homogenous, and 11 of 25 (44%) AIP were homogenous (P < 0.05). A capsule-like rim was present in 9 of 25 (36%) AIP, but was not seen in lymphomas (P < 0.05). On dynamic MRI, 18 of 19 (94.7%) AIP showed persistent (n = 5) or delayed enhancement (n = 13), and 6 of 8 (75%) lymphomas showed low intensity without delayed enhancement (P < 0.001). Conclusion: MRI findings for pancreatic lymphomas and AIP were significantly different, which may be helpful for the differential diagnosis of these two diseases.

Ishigami, Kousei, E-mail: Ishigamikousei@aol.co [Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582 (Japan); Tajima, Tsuyoshi; Nishie, Akihiro; Ushijima, Yasuhiro [Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582 (Japan); Fujita, Nobuhiro [Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University (Japan); Asayama, Yoshiki; Kakihara, Daisuke; Irie, Hiroyuki [Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582 (Japan); Ito, Tetsuhide; Igarashi, Hisato [Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University (Japan); Nakamura, Masafumi [Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University (Japan); Honda, Hiroshi [Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582 (Japan)

2010-06-15

318

MRI brain findings in ephedrone encephalopathy associated with manganese abuse: Single-center perspective  

Science.gov (United States)

Summary Background Manganese (Mn) is a well-known toxic agent causing symptoms of parkinsonism in employees of certain branches of industry. Home production of a psychostimulant ephedrone (methcathinone), involving the use of potassium permanganate, became a new cause of intoxications in Poland. Case Report This article presents clinical symptoms, initial brain MRI findings and characteristics of changes observed in follow-up examinations in 4 patients with manganese intoxication associated with intravenous administration of ephedrone. All patients in our case series presented symptoms of parkinsonism. T1-WI MRI revealed high intensity signal in globi pallidi in all patients; hyperintense lesions in midbrain were observed in three patients, while lesions located in cerebellar hemispheres and pituitary gland in just one patient. The reduction of signal intensity in the affected brain structures was observed in follow-up studies, with no significant improvement in clinical symptoms. Conclusions Brain MRI is helpful in the assessment of distribution as well as dynamics of changes in ephedrone encephalopathy. Regression of signal intensity changes visible in brain MRI is not associated with clinical condition improvement. Although brain MRI findings are not characteristic for ephedrone encephalopathy, they may contribute to diagnosing this condition. PMID:24963359

Poniatowska, Renata; Lusawa, Ma?gorzata; Skierczy?ska, Agnieszka; Makowicz, Grzegorz; Habrat, Bogus?aw; Sienkiewicz-Jarosz, Halina

2014-01-01

319

Cine magnetic resonance imaging for evaluating flow dynamics in congenital heart diseases with left-to-right shunts  

International Nuclear Information System (INIS)

Cine magnetic resonance imaging (cine MRI) was used to evaluate the cardiac structures and blood flow in congenital heart diseases with left-to-right shunts. Fifteen children with left-to-right shunts which were confirmed by echocardiography or angiography were investigated in the present study. Five children each had atrial septal defect, ventricular septal defect, and complete endocardial cushion defect. Their ages ranged from 4 months to 13 years (mean 5.5 years). Prior to cine MRI, the ECG-gated cardiac imaging using multi-slice acquisition was performed in all the children to localize the optimal slice for cine MRI. To select the optimal imaging planes for various cardiac structures, we used axial, coronal, sagittal and four-chamber views. Cine MRI was demonstrated by a fast low 30 degree flip angle imaging technique, with a 15 msec echo time, a 30?40 msec pulse repetition time, and a 256x256 or 128x128 acquisition matrix. Abnormalities of cardiac structures were defined extremely well in all the children using ECG-gated cardiac imaging. In 14 of the 15 children (93%), cine MRI clearly detected a left-to-right shunt flow, which was visualized as a low signal intensity area compared to the surrounding blood flow. Noninvasively, cine MRI provides accurate images of the anatomy of the cardiac structures, makes functional assessments of the cardiac chambers and walls, and flow relationships. It has no limitations of imaging planes imposed bones and lung, and is notlanes imposed bones and lung, and is not associated with technical difficulties as required with echocardiography which has small cardiac window. We conclude that cine MRI will become one of the most important noninvasive techniques for diagnosing congenital heart diseases with left-to-right shunts. (author)

320

Clinical, MRI and perfusion SPECT findings in strategic infarct dementia  

Energy Technology Data Exchange (ETDEWEB)

Strategic infarct dementia (SID) is characterized by focal ischemic lesions involving specific sites that are critical for higher cortical functions. The mechanism of SID are not well understood. We evaluate lesion sites, neuropsychiatric symptoms, brain perfusion SPECT and neuropsychological findings in patients with SID. Eleven patients with SID according to NINDS-AIREN criteria for vascular dementia were included. All patients performed brain MR and MRA, Tc-99m HMPAO brain perfusion SPECT. Various sites were responsible for SID; thalamus(n=3), medial temporal lobe(n=3), medial frontal lobe(n=1), genu of internal capsule(n=1), caudate nucleus(n=1), angular gyrus(n=1) and temporooccipital lobe(n=1). The most common neuropsychiatric symptoms were apathy and indifference by K-NPI. Brain perfusion SPECT revealed ipsilateral cortical hypoperfusion, mainly in frontal and temporal lobe area, in patients with subcortical strategic infarct. On neuropsychological assessment, cognitive deficits on attention and frontal executive function were prominent. The thalamus and medial temporal lobe were the most common sites responsible for SID. It was suggested that strategic disruption of frontal-subcortical circuit be an important role to produce SID in patients with subcortical strategic lesions.

Kang, Do Young; Park, Kyung Won; Cha, Jae Kwan; Kim, Sang Ho; Kim, Jae Woo [Dong-A University College of Medicine, Busan (Korea, Republic of)

2002-07-01

321

Clinical, MRI and perfusion SPECT findings in strategic infarct dementia  

International Nuclear Information System (INIS)

Strategic infarct dementia (SID) is characterized by focal ischemic lesions involving specific sites that are critical for higher cortical functions. The mechanism of SID are not well understood. We evaluate lesion sites, neuropsychiatric symptoms, brain perfusion SPECT and neuropsychological findings in patients with SID. Eleven patients with SID according to NINDS-AIREN criteria for vascular dementia were included. All patients performed brain MR and MRA, Tc-99m HMPAO brain perfusion SPECT. Various sites were responsible for SID; thalamus(n=3), medial temporal lobe(n=3), medial frontal lobe(n=1), genu of internal capsule(n=1), caudate nucleus(n=1), angular gyrus(n=1) and temporooccipital lobe(n=1). The most common neuropsychiatric symptoms were apathy and indifference by K-NPI. Brain perfusion SPECT revealed ipsilateral cortical hypoperfusion, mainly in frontal and temporal lobe area, in patients with subcortical strategic infarct. On neuropsychological assessment, cognitive deficits on attention and frontal executive function were prominent. The thalamus and medial temporal lobe were the most common sites responsible for SID. It was suggested that strategic disruption of frontal-subcortical circuit be an important role to produce SID in patients with subcortical strategic lesions

322

MRI findings of ovarian tumors : differentiation of benign from malignant lesions  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the usefulness of MRI findings in the differentiation of benign from malignant ovarian lesions. Using MR findings, 29 surgically proven ovarian masses in 22 patients (14 bilateral tumors) were evaluated Twenty-one benign tumors in 16 patients(5 simple cysts, 4 mucinous cystadenomas, 4 serous cystadenomas, 4 endometriomas, 3 cystic teratomas and 1 tuboovarian abscess), and eight malignant tumors in six patients(4 serous papillary cystadenocarcinomas and 4 mucinous cystadenocarcinomas) were included. MRI was performed with SE T1WI, FSE T2WI and Gd-T1WI. MRI findings of lesion size, thickness of wall and of internal septations, number of internal septations, nodularities, and ancillary findings such as adhesion in the pelvic cavity, dissemination, ascites and 1ymphadenopathy were retrospectively analyzed. Malignant ovarian lesions were larger(18cm : 11cm) and had more internal septations, more solid components and nodularities(63% : 5%) than benign lesions. On T1WI, cystic lesions, both benign and malignant, showed low signal intensity. Hemorrhage, fat components and mucin containing lesions showed high signals and solid components and nodularities were isointense with muscle on T1WI. Solid components and nodularities were well-enhanced after gadolinium enhancement. Adhesion(50% : 10%), dissemination(38% : 0%) and ascites(63% : 24%) were more frequent in malignant lesions. MRI, especially with gadolinium-enhanced T1WI is useful in the differentiation of benign from malignant ovarian lesions.

Yun, Hee Ja; Lee, Min Hee; Lim, Soo Mi; Kim, Hyae Young; Baek, Seung Yon; Lee, Sun Wha [Ewha Womans Univ. College of Medicine, Seoul (Korea, Republic of); Ko, Eun Joo [Eulgi Medical Center, Seoul (Korea, Republic of); Lee, Myung Sook [Samsung Cheil Hospital, Seoul (Korea, Republic of)

1997-05-01

323

Pituitary duplication and nasopharyngeal teratoma in a newborn: CT, MRI, US and correlative histopathological findings  

Energy Technology Data Exchange (ETDEWEB)

The computed tomography and MRI imaging findings in a case of pituitary duplication and epipharyngeal teratoma are described in a newborn baby girl with respiratory difficulties. Associated skull base and central nervous system malformations are presented. Teratoma diagnosis was confirmed by histology. The embryological pathogenesis is discussed. (orig.)

Huisman, Thierry A.G.M.; Straube, Torsten [University Children' s Hospital Zurich, Department of Diagnostic Imaging, Zurich (Switzerland); Fischer, Ursin; Gysin, Claudine [University Children' s Hospital Zurich, Division of Ear, Nose and Throat Surgery, Zurich (Switzerland); Boltshauser, Eugen [University Children' s Hospital Zurich, Department of Neurology, Zurich (Switzerland)

2005-07-01

324

MRI Findings of Coexistence of Ectopic Neurohypophysis, Corpus Callosum Dysgenesis, and Periventricular Neuronal Heterotopia  

Science.gov (United States)

Ectopic neurohypophysis is a pituitary gland abnormality, which can accompany growth hormone deficiency associated with dwarfism. Here we present magnetic resonance imaging (MRI) findings of a rare case of ectopic neurohypophysis, corpus callosum dysgenesis, and periventricular neuronal heterotopia coexisting, with a review of the literature. PMID:24987569

Arslan, Harun; Sayl?k, Metin; Akdeniz, Hüseyin

2014-01-01

325

MRI findings on iatrogenic spinal infection following various pain management procedures  

International Nuclear Information System (INIS)

The aim of this study was to investigate and report magnetic resonance imaging (MRI) findings of iatrogenic spinal infection (ISI). We retrospectively reviewed the clinical and MRI findings on 18 patients diagnosed with ISI. The MRI findings were evaluated for the number of spinal segments showing inflammation in the longitudinal span and affected vertebral bodies and discs, the presence of abscess in the epidural or paravertebral space, paravertebral myositis, and skip lesions. Among the 18 patients, the range of the longitudinal span of spinal inflammation was 2-11 (mean = 5.84) vertebral segments. 17 of the 18 patients had three or more contiguous vertebral segments. The osteomyelitis and disc destruction was apparent in 77.8% and 66.7% of the patients, and 78% of patients with osteomyelitis showed involvement of one or two vertebrae; 91.7% of patients with disc destruction showed involvement of single disc. The incidence of epidural or paravertebral abscesses, and paravertebral myositis were 88.9%, and 94.4%. There were no spinal skip lesions. MRI findings of those are wide longitudinal span of infection, involvement of no more than one or two vertebral bodies and a single disc, large abscesses, extensive myositis and no skip lesions, can be a useful ISI-diagnostic tool.

326

MRI findings of extramedullary hematopoiesis of the spleen in patient with idiopathic myelofibrosis : 2 case report  

International Nuclear Information System (INIS)

MRI findings of extramedullary hematopoiesis of the spleen have not been described in the literature. We report the MRI features of this condition, as seen in two patients and confirmed by fine needle biopsy. Three small masses (? 3 cm) were isointense on T1WI, hyperintense on T2WI, and enhance after the injection of gadolinium. Two 6 cm-sized masses were by hypointense on both T1WI and T2WI, and showed no contrast enhancement. (author). 9 refs., 2 figs

327

MRI findings of extramedullary hematopoiesis of the spleen in patient with idiopathic myelofibrosis : 2 case report  

Energy Technology Data Exchange (ETDEWEB)

MRI findings of extramedullary hematopoiesis of the spleen have not been described in the literature. We report the MRI features of this condition, as seen in two patients and confirmed by fine needle biopsy. Three small masses ({<=} 3 cm) were isointense on T1WI, hyperintense on T2WI, and enhance after the injection of gadolinium. Two 6 cm-sized masses were by hypointense on both T1WI and T2WI, and showed no contrast enhancement. (author). 9 refs., 2 figs.

Kim, Hyoung Seuk; Park, Cheol Min; Cha, In Ho; Kim, Ae Ree [Korea Univ., Seoul (Korea, Republic of). Coll. of Medicine; Lee, Moon Gyu; Auh, Yong Ho [Asan Medical Center, Seoul (Korea, Republic of). Coll. of Medicine

1998-03-01

328

Tuberculous adenitis: comparison of CT and MRI findings with histopathological features  

Energy Technology Data Exchange (ETDEWEB)

Our aim was to investigate the relationship between the various histopathological features and the CT and MRI findings in routinely submitted histopathological specimens for the diagnosis of tuberculous lymphadenopathy. Twelve formalin-fixed, paraffin-embedded tissue blocks from ten patients who were clinically suspected of having tuberculous lymphadenopathy were evaluated. We assessed the presence of histopathological features including granuloma formation, caseous necrosis, and presence of Langhans-type giant cells, calcifications, fibrosis or normal lymphoid tissue. We performed polymerase chain reaction (PCR)-based assay for mycobacterial DNA and Ziehl-Neelsen staining for acid-fast bacilli (AFB). Findings were compared with those of CT and MRI, including signal intensities on unenhanced MR images, lymph node homogeneity, attenuation values on contrast-enhanced CT and enhancement patterns on MRI. Based on CT and MRI findings, four lymph node types could be defined: (1) homogeneous nodes, visible on both pre- and post-contrast images and corresponding histopathologically to granulation tissue without or with minimal caseation necrosis (n = 2); (2) heterogeneous nodes, showing heterogeneous enhancement patterns with central non-enhancing areas and corresponding to minor or moderate intranodal caseation/liquefaction necrosis (n = 3); (3) nodes showing peripheral rim enhancement and corresponding to moderate or extensive intranodal caseation/liquefaction necrosis (n = 5); (4) heterogeneous nodes showing intranodal hyperdensities on CT and hypointense areas on T1- and T2-weighted images and corresponding to fibrosis and calcifications (n = 2). On CT and MRI, the findings reflect different stages of the tuberculous process. Imaging findings depend on the presence and the degree of granuloma formation, caseation/liquefaction necrosis, fibrosis and calcifications. (orig.)

Backer, A.I. de [General Hospital Sint-Lucas, Department of Radiology, Ghent (Belgium); Mortele, K.J. [Harvard Medical School, Department of Radiology, Division of Abdominal Imaging and Intervention, Brigham and Women' s Hospital, Boston, MA (United States); Heuvel, E. van den [University Hospital of Antwerp, Department of Pathology, Edegem (Belgium); Vanschoubroeck, I.J. [Ziekenhuisnetwerk Antwerpen, Stuivenberg, Department of Internal Medicine, Antwerp (Belgium); Kockx, M.M. [Ziekenhuisnetwerk Antwerpen, Stuivenberg, Department of Pathology, Antwerp (Belgium); Vyvere, M. van de [Ziekenhuisnetwerk Antwerpen, Stuivenberg, Department of Microbiology, Antwerp (Belgium)

2007-04-15

329

MRI findings in 6 cases of children by inadvertent ingestion of diphenoxylate-atropine  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Compound diphenoxylate (diphenoxylate-atropine) poisoning can cause toxic encephalopathy in children, and magnetic resonance imaging (MRI) of the brain in this condition has not been reported. This study is to analyze brain MRI findings and to investigate the relations between MRI features and possible pathophysiological changes in children. Methods: Six children accidentally swallowed compound diphenoxylate, 4 males, 2 females, aged 20-46 months, average 33 months. Quantity of ingested diphenoxylate-atropine was from 6 to 30 tablets, each tablet contains diphenoxylate 2.5 mg and atropine 0.025 mg. These patients were referred to our hospital within 24 h after diphenoxylate-atropine ingestion, and underwent brain MRI scan within 24-72 h after emergency treatment. The characteristics of conventional MRI were analyzed. Results: These pediatric patients had various symptoms of opioid intoxication and atropine toxicity. Brain MRI showed abnormal low signal intensity on T1-weighted images (T1WI) and abnormal high signal intensity on T2-weighted images (T2WI) and fluid-attenuated inversion recovery (FLAIR) imaging in bilateral in all cases; abnormal high signal intensity on T1WI, T2WI and FLAIR in 4 cases. Encephalomalacia was observed in 3 cases during follow-up. Conclusion: In the early stage of compound diphenoxylate poisoning in children, multiple extensive edema-necrosis and hemorrhagic-necrosis focus were observed in basic nucleus, pallium and cerebellum, these resulted in the corresponding brain dysfunction with encephalomalacia. MRI scan in the early stage in this condition may provide evidences of brain impairment, and is beneficial for the early diagnosis, treatment and prognosis assessment.

Xiao Lianxiang [Shandong University School of Medicine, Shandong Medical Imaging Research Institute , No. 44 West Wenhua Road, Jinan 250012 (China); Lin Xiangtao, E-mail: yishui1982@126.com [Shandong University School of Medicine, Shandong Medical Imaging Research Institute, No. 44 West Wenhua Road, Jinan 250012 (China); Cao Jinfeng [Shandong University School of Medicine, Shandong Medical Imaging Research Institute , No. 44 West Wenhua Road, Jinan 250012 (China); Wang Xueyu [Division of Pediatrics, Shandong Provincial Hospital, Shandong University, No. 324 Jingwu Road, Jinan 250021 (China); Wu Lebin [Shandong Medical Imaging Research Institute, No. 324 Jingwu Road, Jinan 250021 (China)

2011-09-15

330

Comparison of MRI and renal cortical scintigraphy findings in childhood acute pyelonephritis: preliminary experience  

International Nuclear Information System (INIS)

Objective: The diagnosis of acute pyelonephritis in children remains a clinical challenge. It may cause permanent renal scar formation and results in the chronic renal failure if prompt diagnosis and treatment are delayed. The purpose of this study is to compare magnetic resonance imaging (MRI) and renal cortical scintigraphy (RCS) findings in childhood acute pyelonephritis and to determine pyelonephritic foci in the acute phase. Materials and method: Twenty children (15 females and five males) with symptoms dysuria, enuresis, costovertebral pain, fever of 37.5 degree sign C or more and/or positive urine culture were imaged by unenhanced turbo spin echo T2, spin echo T1-weighted, pre- and post-gadolinium inversion recovery MRI and RCS. Both imaging techniques were read independently by two radiologists and nuclear medicine specialists. Sensitivity and specificity of MRI in detecting acute pyelonephritic foci and scar lesions were calculated. Furthermore, in order to calculate the reliability of MRI over RCS in differentiating scar tissue and acute pyelonephritic foci, follow-up MRI studies were done in six patients after treatment of acute pyelonephritis. Results: Sensitivity and specificity of MRI in the detection of pyelonephritic lesions were found to be 90.9 and 88.8%, respectively. There is no statistically significant difference in lesion detection between the two diagnostic modalities (P>0.05). Conclusion: Post-gadolinium MR images show significant correlation um MR images show significant correlation with RCS in the determination of renal pathology. Moreover, the ability of discriminating acute pyelonephritic foci and renal scar in early stages of disease is the superiority of MRI

331

Comparison of MRI and renal cortical scintigraphy findings in childhood acute pyelonephritis: preliminary experience  

Energy Technology Data Exchange (ETDEWEB)

Objective: The diagnosis of acute pyelonephritis in children remains a clinical challenge. It may cause permanent renal scar formation and results in the chronic renal failure if prompt diagnosis and treatment are delayed. The purpose of this study is to compare magnetic resonance imaging (MRI) and renal cortical scintigraphy (RCS) findings in childhood acute pyelonephritis and to determine pyelonephritic foci in the acute phase. Materials and method: Twenty children (15 females and five males) with symptoms dysuria, enuresis, costovertebral pain, fever of 37.5 degree sign C or more and/or positive urine culture were imaged by unenhanced turbo spin echo T2, spin echo T1-weighted, pre- and post-gadolinium inversion recovery MRI and RCS. Both imaging techniques were read independently by two radiologists and nuclear medicine specialists. Sensitivity and specificity of MRI in detecting acute pyelonephritic foci and scar lesions were calculated. Furthermore, in order to calculate the reliability of MRI over RCS in differentiating scar tissue and acute pyelonephritic foci, follow-up MRI studies were done in six patients after treatment of acute pyelonephritis. Results: Sensitivity and specificity of MRI in the detection of pyelonephritic lesions were found to be 90.9 and 88.8%, respectively. There is no statistically significant difference in lesion detection between the two diagnostic modalities (P>0.05). Conclusion: Post-gadolinium MR images show significant correlation with RCS in the determination of renal pathology. Moreover, the ability of discriminating acute pyelonephritic foci and renal scar in early stages of disease is the superiority of MRI.

Kovanlikaya, Arzu; Okkay, Nese; Cakmakci, Handan E-mail: cakmakh@egenet.com.tr; Oezdogan, Oezhan; Degirmenci, Berna; Kavukcu, Salih

2004-01-01

332

MRI in late sequelae of Perthes' disease: imaging findings and symptomatology in ten hips  

International Nuclear Information System (INIS)

Five painful (group A) and five symptomless (group B) hips in nine patients with late sequelae of Perthes' disease were studied with plain radiography and magnetic resonance imaging (MRI) in order to correlate MRI findings with symptomatology. The unaffected hips were also studied. In group A hips, poor congruence of the articular cartilage surfaces was present in three of five cases, whereas good congruence was found in all group B hips. In one spherical but painful hip (group A), MRI revealed a protuberance in the anterolateral cartilage of the femoral head. The joint cartilage in group A and B hips was, on average, 0.5 and 1.5 mm thicker, respectively, than the cartilage in the unaffected hips. The lateral joint capsule was, on average, 3.0 mm thicker in group A hips than in the unaffected hips (P < 0.05), which possibly reflects reactive changes due to chronic irritation in the painful hips. The mean joint capsule thickness differed by only 0.5 mm between the unaffected and group B hips. Mean anterior acetabular coverage by MRI was 97 % in group A and 98 % in group B, while in the unaffected hips mean anterior coverage was 102 %. In an aspherical painful hip, MRI revealed a juxta-articular cyst not visible by radiography. A symptomless intra-articular fragment, due to osteochondritis dissecans, was well visualized with MRI. MRI is recommended for evaluation of pain in hips with late sequelae of Perthes' disease. It may show abnormalities in bony structures, as welw abnormalities in bony structures, as well as in joint capsule and cartilage. (orig.). With 5 figs., 1 tab

333

MRI findings in 6 cases of children by inadvertent ingestion of diphenoxylate-atropine  

International Nuclear Information System (INIS)

Purpose: Compound diphenoxylate (diphenoxylate-atropine) poisoning can cause toxic encephalopathy in children, and magnetic resonance imaging (MRI) of the brain in this condition has not been reported. This study is to analyze brain MRI findings and to investigate the relations between MRI features and possible pathophysiological changes in children. Methods: Six children accidentally swallowed compound diphenoxylate, 4 males, 2 females, aged 20-46 months, average 33 months. Quantity of ingested diphenoxylate-atropine was from 6 to 30 tablets, each tablet contains diphenoxylate 2.5 mg and atropine 0.025 mg. These patients were referred to our hospital within 24 h after diphenoxylate-atropine ingestion, and underwent brain MRI scan within 24-72 h after emergency treatment. The characteristics of conventional MRI were analyzed. Results: These pediatric patients had various symptoms of opioid intoxication and atropine toxicity. Brain MRI showed abnormal low signal intensity on T1-weighted images (T1WI) and abnormal high signal intensity on T2-weighted images (T2WI) and fluid-attenuated inversion recovery (FLAIR) imaging in bilateral in all cases; abnormal high signal intensity on T1WI, T2WI and FLAIR in 4 cases. Encephalomalacia was observed in 3 cases during follow-up. Conclusion: In the early stage of compound diphenoxylate poisoning in children, multiple extensive edema-necrosis and hemorrhagic-necrosis focus were observed in basic nucleus, pallium and cerebellum, thebasic nucleus, pallium and cerebellum, these resulted in the corresponding brain dysfunction with encephalomalacia. MRI scan in the early stage in this condition may provide evidences of brain impairment, and is beneficial for the early diagnosis, treatment and prognosis assessment.

334

Desmoplastic fibroma of bone in a toe: Radiographic and MRI findings  

Energy Technology Data Exchange (ETDEWEB)

Desmoplastic fibroma is a rare benign primary bone tumor that is histologically similar to the soft tissue desmoid tumor. It most often involves the mandible, large long bone or iliac bone. Desmoplastic fibroma in a toe has been extremely rarely reported. Authors report a rare case of desmoplastic fibroma of bone occurring in the distal phalanx of a foot, with descriptions of the radiographic and MRI findings, correlation of the radiologic and pathologic findings, and discussion on the differential diagnosis of the tumor.

Kim, Ok Hwa; Kim, Seon Jeong; Kim Ji Yeon; Ryu, Ji Hwa [Inje University, Haeundae Paik Hospital, Busan (Korea, Republic of); Choo, Hye Jung [Dept. of Radiology, Inje University, Busan Paik Hospital, Busan (Korea, Republic of); Lee, In Sook [Dept. of Radiology, Busan National University Hospital, Busan (Korea, Republic of); Suh, Kyung Jin [Dept. of Radiology, Dongguk University, Gyeongju Hospital, Gyeongju (Korea, Republic of)

2013-12-15

335

Desmoplastic Fibroma of Bone in a Toe: Radiographic and MRI Findings  

OpenAIRE

Desmoplastic fibroma is a rare benign primary bone tumor that is histologically similar to the soft tissue desmoid tumor. It most often involves the mandible, large long bone or iliac bone. Desmoplastic fibroma in a toe has been extremely rarely reported. Authors report a rare case of desmoplastic fibroma of bone occurring in the distal phalanx of a foot, with descriptions of the radiographic and MRI findings, correlation of the radiologic and pathologic findings, and discussion on the differ...

Kim, Ok Hwa; Kim, Seon Jeong; Kim, Ji Yeon; Ryu, Ji Hwa; Choo, Hye Jung; Lee, Sun Joo; Lee, In Sook; Suh, Kyung Jin

2013-01-01

336

Desmoplastic fibroma of bone in a toe: Radiographic and MRI findings  

International Nuclear Information System (INIS)

Desmoplastic fibroma is a rare benign primary bone tumor that is histologically similar to the soft tissue desmoid tumor. It most often involves the mandible, large long bone or iliac bone. Desmoplastic fibroma in a toe has been extremely rarely reported. Authors report a rare case of desmoplastic fibroma of bone occurring in the distal phalanx of a foot, with descriptions of the radiographic and MRI findings, correlation of the radiologic and pathologic findings, and discussion on the differential diagnosis of the tumor.

337

TRUS, CT and MRI findings of hydatid disease of seminal vesicles  

Energy Technology Data Exchange (ETDEWEB)

Hydatid disease of the urogenital system, especially seminal vesicles and prostate, or retroperitoneum is a very rare condition. Secondary dissemination of seminal vesicles has not been described before. We describe the transrectal ultrasonography (TRUS), CT and MRI findings of a secondary solitary hydatid cyst of the left seminal vesicle, in a patient with disseminated hydatid disease involving all abdominal organs except for right kidney. We obtained typical findings of hydatid cyst at all modalities. (orig.) With 3 figs., 11 refs.

Saglam, M.; Tasar, M.; Bulakbasi, N.; Tayfun, C.; Somuncu, I. [Department of Diagnostic Radiology, Guelhane Military Medical Academy and Medical School, Ankara (Turkey)

1998-07-01

338

TRUS, CT and MRI findings of hydatid disease of seminal vesicles  

International Nuclear Information System (INIS)

Hydatid disease of the urogenital system, especially seminal vesicles and prostate, or retroperitoneum is a very rare condition. Secondary dissemination of seminal vesicles has not been described before. We describe the transrectal ultrasonography (TRUS), CT and MRI findings of a secondary solitary hydatid cyst of the left seminal vesicle, in a patient with disseminated hydatid disease involving all abdominal organs except for right kidney. We obtained typical findings of hydatid cyst at all modalities. (orig.)

339

Incidental findings in healthy control research subjects using whole-body MRI  

Energy Technology Data Exchange (ETDEWEB)

Aim: Magnetic resonance imaging (MRI) is a powerful clinical tool used increasingly in the research setting. We aimed to assess the prevalence of incidental findings in a sequential cohort of healthy volunteers undergoing whole-body MRI as part of a normal control database for imaging research studies. Materials and methods: 148 healthy volunteers (median age 36 years, range 21-69 years; 63.5% males, 36.5% females) were enrolled into a prospective observational study at a single hospital-based MRI research unit in London, UK. Individuals with a clinical illness, treated or under investigation were excluded from the study. Results: 43 (29.1%) scans were abnormal with a total of 49 abnormalities detected. Of these, 20 abnormalities in 19 patients (12.8%) were of clinical significance. The prevalence of incidental findings increased significantly with both increasing age and body mass index (BMI). Obese subjects had a fivefold greater risk of having an incidental abnormality on MRI (OR 5.4, CI 2.1-14.0). Conclusions: This study showed that more than one quarter of healthy volunteers have MR-demonstrable abnormalities. There was an increased risk of such findings in obese patients. This has ethical and financial implications for future imaging research, particularly with respect to informed consent and follow-up of those with abnormalities detected during the course of imaging studies.

Morin, S.H.X. [Division of Medicine, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN (United Kingdom); Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN (United Kingdom)], E-mail: s.morin@imperial.ac.uk; Cobbold, J.F.L. [Division of Medicine, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN (United Kingdom)], E-mail: j.cobbold@imperial.ac.uk; Lim, A.K.P. [Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN (United Kingdom)], E-mail: a.lim@imperial.ac.uk; Eliahoo, J. [Statistical Advisory Service, Imperial College London, South Kensington Campus, Room G05, Sir Alexander Fleming Building, London SW7 2AZ (United Kingdom)], E-mail: j.eliahoo@imperial.ac.uk; Thomas, E.L. [Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN (United Kingdom)], E-mail: louise.thomas@imperial.ac.uk; Mehta, S.R. [Division of Medicine, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN (United Kingdom)], E-mail: s.mehta@imperial.ac.uk; Durighel, G. [Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN (United Kingdom)], E-mail: g.durighel@imperial.ac.uk; Fitzpatrick, J. [Division of Medicine, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN (United Kingdom); Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN (United Kingdom)], E-mail: j.fitzpatrick@imperial.ac.uk; Bell, J.D. [Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Campus, London W12 0NN (United Kingdom)], E-mail: j.bell@imperial.ac.uk (and others)

2009-12-15

340

Incidental findings in healthy control research subjects using whole-body MRI  

International Nuclear Information System (INIS)

Aim: Magnetic resonance imaging (MRI) is a powerful clinical tool used increasingly in the research setting. We aimed to assess the prevalence of incidental findings in a sequential cohort of healthy volunteers undergoing whole-body MRI as part of a normal control database for imaging research studies. Materials and methods: 148 healthy volunteers (median age 36 years, range 21-69 years; 63.5% males, 36.5% females) were enrolled into a prospective observational study at a single hospital-based MRI research unit in London, UK. Individuals with a clinical illness, treated or under investigation were excluded from the study. Results: 43 (29.1%) scans were abnormal with a total of 49 abnormalities detected. Of these, 20 abnormalities in 19 patients (12.8%) were of clinical significance. The prevalence of incidental findings increased significantly with both increasing age and body mass index (BMI). Obese subjects had a fivefold greater risk of having an incidental abnormality on MRI (OR 5.4, CI 2.1-14.0). Conclusions: This study showed that more than one quarter of healthy volunteers have MR-demonstrable abnormalities. There was an increased risk of such findings in obese patients. This has ethical and financial implications for future imaging research, particularly with respect to informed consent and follow-up of those with abnormalities detected during the course of imaging studies.

341

MRI of double-bundle ACL reconstruction: evaluation of graft findings  

Energy Technology Data Exchange (ETDEWEB)

To demonstrate the magnetic resonance imaging (MRI) findings of double-bundle (DB) anterior cruciate ligament (ACL) reconstruction grafts. Sixty-six patients with DB ACL reconstruction were evaluated with MRI 2 years postoperatively. Graft thickness was measured separately by two musculoskeletal radiologists. The MRI findings of graft disruption, signal intensity (SI) changes, cystic degeneration, arthrofibrosis, and impingement were analyzed. The statistical significance of the association between MRI findings was calculated. The mean anteromedial (AM) graft thickness was reduced 9% and the mean posterolateral (PL) graft thickness was reduced 18% from the original graft thickness. Disruption was seen in 3% of AM grafts and 6% of PL grafts and a partial tear in 8 and 23%, respectively. Both grafts were disrupted in 3% of patients. Increased SI was seen in 14% of intact AM grafts and in 60% of partially torn AM grafts (p = 0.032). In PL grafts the increased SI was seen in 51% of the intact grafts and in 93% of the partially torn grafts (p = 0.005). Cystic degeneration was seen in 8% of AM grafts and in 5% of PL grafts. Diffuse arthrofibrosis was seen in 5% of patients and a localized cyclops lesion in 3% of patients. Impingement of the AM graft was seen in 8% of patients. Both grafts were disrupted in 3% of patients. Also, the frequencies of other complications were low. The use of orthogonal sequences in the evaluation of the PL graft SI seems to cause volume-averaging artefacts. (orig.)

Kiekara, Tommi; Paakkala, Antti [Tampere University Hospital, Medical Imaging Centre, Tampere (Finland); Jaervelae, Timo [Sports Clinic and Hospital Mehilaeinen, Tampere (Finland); Huhtala, Heini [University of Tampere, School of Health Sciences, Tampere (Finland)

2012-07-15

342

Brain MRI findings of welders : high signal intensity in T1WI secondary to manganese exposure  

International Nuclear Information System (INIS)

To evaluate the clinical and brain MRI findings of welders and to determine the utility of MRI in the assessment of occupational manganese exposure. All welders complained of fatigue, headache, anorexia, and decreased libido. The palmomental reflex was positive in five (28%), Myerson's sign in four (22%), and intention tremor in three (17%). Mean blood Mn was 5.18 (range, 1.77-9.34) ?g/dl, mean urine Mn was 5.84 (range, 1.07 -22) ?g/l, serum Fe was elevated in one welder, and serum Cd in two. T1WI of brain MRI revealed high signal intensities in the globus pallidus, the putamen, the substantia nigra, the tectum, the caudate nucleus, the subthalamic nucleus, the hypothalamus and the pituitary gland. These intensities correlated closely with blood Mn levels, suggesting their potential role in estimating the accumulation of Mn in the brain. (author). 25 refs., 2 tabs., 5 figs

343

Brain CT and MRI findings of a long-term case of subacute sclerosing panencephalitis  

Energy Technology Data Exchange (ETDEWEB)

Our study involved a long-term case (ten years) of subacute sclerosing panencephalitis. The case began with a 23 year-old experiencing visual deterioration. During the course of his illness, amnesia, autism and abnormal behavior were observed without any myoclonus. On the electroencephalogram, periodic synclonous discharge was shown in the early stage of his illness and subsequently disappeared. The brain CT and the MRI disclosed diffuse lesions in both cortical and subcortical areas of the cerebral hemispheres. The location and spread of lesions were more clearly revealed by the MRI than the brain CT. These findings suggest that the MRI is more useful than the brain CT in the diagnosis of subacute sclerosing panencephalitis.

Aoshiba, Kazunori; Ota, Kohei; Komatsuzaki, Satoshi; Kobayashi, Itsuro; Maruyama, Shoichi

1987-11-01

344

Brain CT and MRI findings of a long-term case of subacute sclerosing panencephalitis  

International Nuclear Information System (INIS)

Our study involved a long-term case (ten years) of subacute sclerosing panencephalitis. The case began with a 23 year-old experiencing visual deterioration. During the course of his illness, amnesia, autism and abnormal behavior were observed without any myoclonus. On the electroencephalogram, periodic synclonous discharge was shown in the early stage of his illness and subsequently disappeared. The brain CT and the MRI disclosed diffuse lesions in both cortical and subcortical areas of the cerebral hemispheres. The location and spread of lesions were more clearly revealed by the MRI than the brain CT. These findings suggest that the MRI is more useful than the brain CT in the diagnosis of subacute sclerosing panencephalitis. (author)

345

Cognitive function and MRI findings in very low birth weight infants  

International Nuclear Information System (INIS)

Twenty-two very low birth weight infants at preschool ages of 5-6 years were studied to clarify the correlation between cognitive function and MRI findings. Cognitive function was evaluated by the Wechsler Intelligence Scale for Children-Revised (WISC-R) and the Frostig developmental test of visual perception. Ventricular enlargement, assessed by the bioccipital index (B.I.) measured on MRI, was correlated to cognitive disorders. Children with periventricular high intensity areas (T2-weighted images) extending from the posterior periventricular region to the parietal lobe tend to highly suffer from cerebral palsy and visuoperceptual impairment. These results indicate that the disorders of cognitive function in very low birth weight infants were caused by a damage of association fibers in periventricular areas which was detectable by MRI. (author)

346

Cognitive function and MRI findings in very low birth weight infants  

Energy Technology Data Exchange (ETDEWEB)

Twenty-two very low birth weight infants at preschool ages of 5-6 years were studied to clarify the correlation between cognitive function and MRI findings. Cognitive function was evaluated by the Wechsler Intelligence Scale for Children-Revised (WISC-R) and the Frostig developmental test of visual perception. Ventricular enlargement, assessed by the bioccipital index (B.I.) measured on MRI, was correlated to cognitive disorders. Children with periventricular high intensity areas (T{sub 2}-weighted images) extending from the posterior periventricular region to the parietal lobe tend to highly suffer from cerebral palsy and visuoperceptual impairment. These results indicate that the disorders of cognitive function in very low birth weight infants were caused by a damage of association fibers in periventricular areas which was detectable by MRI. (author)

Imamura, Atsuko; Takagishi, Yuka; Takada, Satoru; Uetani, Yoshiyuki; Nakamura, Toru; Nakamura, Hajime [Kobe Univ. (Japan). School of Medicine; Inagaki, Yuko

1996-07-01

347

Brain MRI findings of welders : high signal intensity in T1WI secondary to manganese exposure  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the clinical and brain MRI findings of welders and to determine the utility of MRI in the assessment of occupational manganese exposure. All welders complained of fatigue, headache, anorexia, and decreased libido. The palmomental reflex was positive in five (28%), Myerson`s sign in four (22%), and intention tremor in three (17%). Mean blood Mn was 5.18 (range, 1.77-9.34) {mu}g/dl, mean urine Mn was 5.84 (range, 1.07 -22) {mu}g/l, serum Fe was elevated in one welder, and serum Cd in two. T1WI of brain MRI revealed high signal intensities in the globus pallidus, the putamen, the substantia nigra, the tectum, the caudate nucleus, the subthalamic nucleus, the hypothalamus and the pituitary gland. These intensities correlated closely with blood Mn levels, suggesting their potential role in estimating the accumulation of Mn in the brain. (author). 25 refs., 2 tabs., 5 figs.

Kim, K. W.; Lim, M. A.; Shon, M. Y.; Lee, S. H.; Ha, D. G.; Kwon, K. R.; Kim, S. S.; Hong, Y. S.; Lee, Y. H. [Sunlin Presbyterian Hospital, Pohang (Korea, Republic of); Cheong, H. K. [Dongguk University, Seoul (Korea, Republic of)

1998-03-01

348

Evaluation of CT Scan and MRI Findings of Pathologically Proved Gliomas in an Iranian Population  

Directory of Open Access Journals (Sweden)

Full Text Available Purpose: The aim of this study was to report the main CT scan and MRI findings of gliomas in a group of Iranian patients. Material and Methods: The MRI and CT scan of 96 pathologically proven patients of gliomas were retrospectively evaluated in a period of five years in our university affiliated hospital. We included all cases who had both CT scan and MRI in our study. Results: Among our patients, 60 (62.5% were male and 36 (37.5% were female. The mean age of our patients was 41.8±19.3 (7-78. The most common location of tumor was in the parietal lobes (54.2% followed by the temporal lobes (52.1%, and the frontal lobes (39.6%. The most common subtype was glioblastoma multiform in 42 patients (43.8%. Edema, cystic formation, and hemorrhage were more frequently found in MRI in comparison with CT scan, while CT scan showed calcification better than MRI. Conclusion: In contrast to many other studies, the most common site of gliomas in our patients was parietal lobes.

Sanei Taheri M

2008-11-01

349

X-ray, CT and MRI findings of synovial tuberculosis in joints  

International Nuclear Information System (INIS)

Objective: To analyze the X-ray, CT and MRI findings of synovial tuberculosis, and to evaluate the role of MRI in diagnosing synovial tuberculosis. Methods: Fourteen cases of synovial tuberculosis comfirmed by operation and pathology were retrospectively analyzed and summarized. All patients were examined by MRI and X-ray, and CT scans were performed in 3 cases. Results: X-ray showed joint swelling (8 cases), articular space narrowing (7 cases), marginal joint erosions (4 cases), and periarticular osteoporosis (9 cases). The joint swelling was detected on CT in all 3 cases, and bony erosion and speckled sequestra were seen in 2 cases. MRI in all of patients showed joint swelling and synovial proliferation in different drgees, demonstrated as heterogeneously low signal on T1WI and slight high signal (7 cases) and obvious high signal (6 cases) on T2WI, and diffuse synovial proliferation was demonstrated as massive and nodular signal in 8 cases. Joint effusion was present in 7 cases as low signal on T1WI and high signal on T2WI. Osseous erosion lesions were seen in 7 cases, and intra-articular cartilage thinned, partly or mostly disappeared in 11 cases. Periarticular bone marrow edema was found in 7 cases. Conclusion: MRI was superior to X-ray and CT in the diagnosis and differential diagnosis of synovial tuberculosis. (authors)

350

The paediatric wrist revisited - findings of bony depressions in healthy children on radiographs compared to MRI  

International Nuclear Information System (INIS)

The presence of erosions is used for diagnosis and monitoring of disease activity in juvenile idiopathic arthritis (JIA). Assessment of carpal bone erosions in children is challenging due to lack of normal references. To define normal appearances of bony depressions in the wrist on radiographs and MRI. MRI and radiography of the wrist were performed in 88 healthy children, 5-15 years of age. We assessed the number of bony depressions within the carpals/proximal metacarpals on both modalities, separately and combined. A total of 75 carpal depressions were identified on radiography compared to 715 on MRI. The number of bony depressions identified radiographically showed no statistically significant difference across age-groups. Within the metacarpals, there was no significant difference between bony depressions identified by MRI or radiography, except at the bases of the second metacarpal. Bony depressions that resemble erosions are normal findings in the wrist in children. MRI identifies more depressions than radiographs in the carpus. Some bony depressions occur at typical locations and should be accounted for when assessing the wrist in JIA to avoid overstaging. (orig.)

351

The paediatric wrist revisited - findings of bony depressions in healthy children on radiographs compared to MRI  

Energy Technology Data Exchange (ETDEWEB)

The presence of erosions is used for diagnosis and monitoring of disease activity in juvenile idiopathic arthritis (JIA). Assessment of carpal bone erosions in children is challenging due to lack of normal references. To define normal appearances of bony depressions in the wrist on radiographs and MRI. MRI and radiography of the wrist were performed in 88 healthy children, 5-15 years of age. We assessed the number of bony depressions within the carpals/proximal metacarpals on both modalities, separately and combined. A total of 75 carpal depressions were identified on radiography compared to 715 on MRI. The number of bony depressions identified radiographically showed no statistically significant difference across age-groups. Within the metacarpals, there was no significant difference between bony depressions identified by MRI or radiography, except at the bases of the second metacarpal. Bony depressions that resemble erosions are normal findings in the wrist in children. MRI identifies more depressions than radiographs in the carpus. Some bony depressions occur at typical locations and should be accounted for when assessing the wrist in JIA to avoid overstaging. (orig.)

Avenarius, Derk M.F.; Eldevik, Petter [University Hospital North Norway, Department of Radiology, Tromsoe (Norway); Ording Mueller, Lil-Sofie [University Hospital North Norway, Department of Radiology, Tromsoe (Norway); Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); Owens, Catherine M. [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); University College London, Institute of Child Health, London (United Kingdom); Rosendahl, Karen [Haukeland University Hospital, Department of Radiology, Bergen (Norway); University of Bergen, Department of Surgical Sciences, Bergen (Norway); Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom)

2012-07-15

352

Hemangioma as an Incidental MRI Finding in 61 Patients of the 3000 Referred Patients for Lumbar Spine MRI in Maragheh MRI Center (2008 Amiralmomenin Hospital  

Directory of Open Access Journals (Sweden)

Full Text Available   "nIntroduction: Hemangiomas of the bone are uncommon tumors exception cranial vault and vertebrae .Multiple lesions are common in the spine. Osseous hemangiomas are relatively common in adults. Rarely the tumor may cause collapse of the vertebral body and result in clinical signs and symptoms of vertebral compression. Hemangiomas are commonly encountered as incidental findings when the spine is examined by MRI. They appear as areas of mixed signal intensity, both intermediate and high, within the vertebral body on T1-weighted images. They are bright high signal on T2. "nMaterials and Methods: Our study is a documented (all images and reports are archived retrospective view on 3000 patients of Maragheh MRI center who were referred to lumbar MRI study for their low back pain. "nResults: 51.3 % of the patients were female and 48.7% were male. Hemangioma is seen in 61 patients (50 single vertebral and 11cases with multilevel lesions. 38 cases were women versus 23 men. Totally 2.46 percent of the referred women and 1.57% of the referred men had hemangioma in their spine. About 2 percent of all patients have shown hemangioma. The incidence of the hemangioma is dominant in women. "nConclusion: Incidence of the multilevel hemangioma is higher in women in our study. No canal and cordal impression was seen in our cases.  

Kourosh Abdollahifard

2009-01-01

353

Brain MRI findings in patients with mucopolysaccharidosis types I and II and mild clinical presentation  

Energy Technology Data Exchange (ETDEWEB)

Our objective was to determine the brain magnetic resonance imaging (MRI) abnormalities in a selected group of patients with mucopolysaccharidosis (MPS) types I and II who had only mild clinical manifestations. We retrospectively assessed MRI brain studies in 18 patients with MPS (type I: 6 and type II: 12). We evaluated abnormal signal intensity in the white matter, widening of the cortical sulci, size of the supratentorial ventricles, dilatation of the perivascular spaces (PVS) and enlargement of the subarachnoid spaces. We observed a broad spectrum of findings, and despite severely abnormal MRI studies, no patients had mental retardation. We also observed that dilated PVS, previously believed to be caused by macroscopic deposition of the mucopolysaccharides, had an appearance similar to cerebrospinal fluid (CSF) in all MRI sequences performed, even in FLAIR and trace diffusion weighted images. Based on our results, we believe that with the exception of white matter abnormalities and brain atrophy, all other findings may be related to abnormal resorption of CSF, and there is no relationship between the imaging and clinical manifestations of the disease. (orig.)

Matheus, M.Gisele; Castillo, Mauricio; Smith, J. Keith [Department of Radiology, University of North Carolina School of Medicine, 27599-7510, Chapel Hill, NC (United States); Armao, Diane [Department of Pathology, University of North Carolina School of Medicine, Chapel Hill, NC (United States); Towle, Diane; Muenzer, Joseph [Department of Genetics and Metabolism, University of North Carolina School of Medicine, Chapel Hill, NC (United States)

2004-08-01

354

A retrospective review of pituitary MRI findings in children on growth hormone therapy  

Energy Technology Data Exchange (ETDEWEB)

Patients with congenital hypopituitarism might have the classic triad of pituitary stalk interruption syndrome, which consists of: (1) an interrupted or thin pituitary stalk, (2) an absent or ectopic posterior pituitary (EPP), and (3) anterior pituitary hypoplasia or aplasia. To examine the relationship between pituitary anatomy and the degree of hormonal dysfunction. This study involved a retrospective review of MRI findings in all children diagnosed with congenital growth hormone deficiency from 1988 to 2010 at a tertiary-level pediatric hospital. Of the 52 MRIs reviewed in 52 children, 26 children had normal pituitary anatomy and 26 had one or more elements of the classic triad. Fourteen of fifteen children with multiple pituitary hormone deficiencies had structural anomalies on MRI. Twelve of 37 children with isolated growth hormone deficiency had an abnormal MRI. Children with multiple pituitary hormone deficiencies were more likely to have the classic triad than children with isolated growth hormone deficiency. A normal MRI was the most common finding in children with isolated growth hormone deficiency. (orig.)

Tsai, Sarah L.; Lawrence, Sarah [University of Ottawa, Division of Endocrinology, Children' s Hospital of Eastern Ontario, Ottawa (Canada); Laffan, Eoghan [Children' s University Hospital, Pediatric Radiology, Dublin 1 (Ireland)

2012-07-15

355

CT and MRI findings of cerebral ischemic lesions in the cortical and perforating arterial system  

International Nuclear Information System (INIS)

It is clinically useful to divide the location of infarction into the cortical and perforating arterial system. Computerized tomography (CT) and magnetic resonance imaging (MRI) now make the point of infarction a simple and useful task in daily practice. The diagnostic modality has also demonstrated that risk factors and clinical manifestations are different for infarction in the cortical as opposed to the perforating system. In this paper, we present various aspects of images of cerebral ischemia according to CT and/or MRI findings. With the advance of imaging mechanics, diagnostic capability of CT or/and MRI for cerebral infarction has markedly been improved. We must consider these points on evaluating the previously reported results. In addition, we always consider the pathological background of these image-findings for the precise interpretation of their clinical significance. In some instances, dynamic study such as PET or SPECT is needed for real interpretations of CT and/or MRI images. We paid special reference to lacunar stroke and striatocapsular infarct. In addition, 'branch atheromatous disease (Caplan)' was considered, in particular, for their specific clinical significances. Large striatocapsular infarcts frequently show cortical signs and symptoms such as aphasia or agnosia in spite of their subcortical localization. These facts, although have previously been known, should be re-considered for their pathoanatomical mechanism. (author)al mechanism. (author)

356

CT and MRI findings of cerebral ischemic lesions in the cortical and perforating arterial system  

Energy Technology Data Exchange (ETDEWEB)

It is clinically useful to divide the location of infarction into the cortical and perforating arterial system. Computerized tomography (CT) and magnetic resonance imaging (MRI) now make the point of infarction a simple and useful task in daily practice. The diagnostic modality has also demonstrated that risk factors and clinical manifestations are different for infarction in the cortical as opposed to the perforating system. In this paper, we present various aspects of images of cerebral ischemia according to CT and/or MRI findings. With the advance of imaging mechanics, diagnostic capability of CT or/and MRI for cerebral infarction has markedly been improved. We must consider these points on evaluating the previously reported results. In addition, we always consider the pathological background of these image-findings for the precise interpretation of their clinical significance. In some instances, dynamic study such as PET or SPECT is needed for real interpretations of CT and/or MRI images. We paid special reference to lacunar stroke and striatocapsular infarct. In addition, `branch atheromatous disease (Caplan)` was considered, in particular, for their specific clinical significances. Large striatocapsular infarcts frequently show cortical signs and symptoms such as aphasia or agnosia in spite of their subcortical localization. These facts, although have previously been known, should be re-considered for their pathoanatomical mechanism. (author).

Kameyama, Masakuni; Udaka, Fukashi; Nishinaka, Kazuto; Kodama, Mitsuo; Urushidani, Makoto; Kawamura, Kazuyuki; Inoue, Haruhisa; Kageyama, Taku [Sumitomo Hospital, Osaka (Japan)

1995-07-01

357

First report of MRI findings in a case of an autoamputated wandering calcified ovary  

Directory of Open Access Journals (Sweden)

Full Text Available Parag Suresh Mahajan, Nazeer Ahamad, Sheik Akbar Hussain Department of Radiology, Al-Khor Hospital, Hamad Medical Corporation, Doha, Qatar Abstract: An autoamputated wandering calcified ovary (AWCO is an extremely rare cause of abdominal calcification in the pediatric population. We present the magnetic resonance imaging (MRI features of AWCO in a child. To our knowledge, the MRI features of AWCO have not been previously described in the published literature. Our case report indicates that the MRI findings are characteristic in the diagnosis of an AWCO and can completely obviate the need for invasive procedures in this mostly benign disease. An AWCO should be considered in all cases of mobile calcific opacities on radiographs in female patients. We advise that MRI be conducted in all suspected cases of AWCO for accurate and noninvasive diagnosis, and regular follow-up should be performed with ultrasound. The findings in our case report have the potential to change the course of investigations and management in suspected cases. Keywords: magnetic resonance imaging, ovary, adnexa, autoamputation, wandering calcification

Mahajan PS

2014-03-01

358

Brain MRI findings in patients with mucopolysaccharidosis types I and II and mild clinical presentation  

International Nuclear Information System (INIS)

Our objective was to determine the brain magnetic resonance imaging (MRI) abnormalities in a selected group of patients with mucopolysaccharidosis (MPS) types I and II who had only mild clinical manifestations. We retrospectively assessed MRI brain studies in 18 patients with MPS (type I: 6 and type II: 12). We evaluated abnormal signal intensity in the white matter, widening of the cortical sulci, size of the supratentorial ventricles, dilatation of the perivascular spaces (PVS) and enlargement of the subarachnoid spaces. We observed a broad spectrum of findings, and despite severely abnormal MRI studies, no patients had mental retardation. We also observed that dilated PVS, previously believed to be caused by macroscopic deposition of the mucopolysaccharides, had an appearance similar to cerebrospinal fluid (CSF) in all MRI sequences performed, even in FLAIR and trace diffusion weighted images. Based on our results, we believe that with the exception of white matter abnormalities and brain atrophy, all other findings may be related to abnormal resorption of CSF, and there is no relationship between the imaging and clinical manifestations of the disease. (orig.)

359

Cine-Club  

CERN Multimedia

Lundi 12 décembre 2011 à 18:30 Salle du Conseil Comme chaque année avant Noël, le CINE-CLUB du CERN est heureux d’inviter petits et grands à une projection gratuite du film : Ponyo sur la falaise (Japon, 2008, Hayao Miyazaki) Le petit Sosuke vit avec sa mère sur une haute falaise surplombant la mer. Un beau jour, il découvre sur la plage caillouteuse Ponyo, une petite fille poisson. Ponyo est si fascinée par Sosuke et le monde terrestre que son désir le plus cher est de devenir un être humain. Mais Fujimoto, son magicien de père, n’est pas du tout d’accord avec cette idée et il la force à regagner les profondeurs de l’océan. Bien décidée à revoir Sosuke, Ponyo s’échappe de sa prison sous-marine, mais ce faisant elle déclenche une immense catastroph...

Cine-Club

2011-01-01

360

Cine-Club  

CERN Document Server

Thursday 10 November 2011 at 20:30 CERN Council Chamber The Counterfeiters / Die Fälscher By: Stefan Ruzowitzky (Germany/Austria, 2007) 98 min With: Karl Markovics, August Diel, Devid Striesow The Counterfeiters is the true story of the largest counterfeiting operation in history, set up by the Nazis in 1936. Master counterfeiter Salomon ‘Sally’ Sorowitsch, a Jew without morals, is arrested and sent to Mauthausen concentration camp, where he weasels through by offering his ‘artistic’ services. After transfer to Sachsenhausen he’s given an official alternative: taking ‘artistic’ charge of a cons teams assigned to produce perfect forgeries of allied banknotes for the Third Reich. Survivor Sally accepts, but conscience matters among the team prove no less dangerous then a sadistic jailer, which only the CO may keep in check. Original version German; English subtitles Entrance: 2 CHF Projection from DVD http://cine...

Cine-Club

2011-01-01

361

Biphosphonate-induced osteonecrosis of the jaws: CT and MRI spectrum of findings in 32 patients  

International Nuclear Information System (INIS)

Aim: To evaluate the computed tomography (CT) and magnetic resonance imaging (MRI) findings of biphosphonate therapy-associated changes of the mandible and maxilla. Materials and Methods: Thirty-two patients with a clinical history of pain, purulent discharge, and swelling in the mandible or maxilla as well as non-healing dental extraction were examined. All patients had received biphosphonate medication for approximately 33 months. Non-contrast enhanced CT and contrast-enhanced MRI were performed and, subsequently, all patients underwent a surgical removal of the affected bone, the histological diagnosis of which confirmed osteonecrosis. The images were read by two head and neck radiologists in consensus. Results: Osteonecrosis with Actinomyces infection was identified in the mandible of 18 patients, in the maxilla of eight patients, and in both jaws in six patients. The CT images showed predominantly osteolytic lesions and sclerotic regions in the jaws with or without periostal bone proliferation. There was a reduction of the marrow space in the jaws. The T1-weighted MRI signal was hypointense in nearly all cases. The gadolinium-enhanced MRI images revealed intensity changes of the cortical and subcortical bone structures in all patients. The T2-weighted MRI signal was hypointense on the affected side in the majority of the cases (28/32). Pathological gadolinium enhancement was observed in the neighbouring soft tissues, including the masticator space in all patientsuding the masticator space in all patients. Reactive lymphadenopathy was found in all patients in submental and jugulodigastric areas. Conclusion: Biphosphonate-induced osteonecrosis of the jaws presents a wide variety of CT and MRI features that are readily recognized and help to determine the extent of the disease; however, they are not specific for the disease

362

Case of dentato-rubro-pallido-luysian atrophy. MRI findings and disturbance of ocular movement  

Energy Technology Data Exchange (ETDEWEB)

A clinical case of dentato-rubro-pallido-luysian atrophy (DRPLA) was reported. We established several aspects on the basis of MRI findings and a neuro-otological study. A 47-year-old woman had gait disturbance, involuntary movements, speech disturbance, and memory disturbance at the age of 42. She was admitted to the hospital because of worsening of the gait disturbance. Neurological examinations showed choreo-athetosis of the face, neck and upper extremities, mental disturbance, and scanning speech. However, she had neither ocular disturbance nor epilepsy or myoclonus. On the MRI-CT, an atrophy of midbrain and pontine tegmentum was observed. The neuro-otological study showed gaze nystagmus at the horizontal gaze, rebound nystagmus, hypometria of the saccade, saccadic pursuit, reduction of the optokinetic nystagmus, and increase in caloric nystagmus by means of visual input. A severe atrophy of the brainstem tegmentum and a mild atrophy of the cerebellar hemisphere and cerebral cortex are regarded as neuro-radiological features of DRPLA. Moreover, tegmental atrophy is related to ocular disturbance as a clinical feature. Various neuro-otological findings reveal many systems of ocular movements, i.e., a smooth pursuit system, a saccade system, and a vestibulo-ocular reflex system, involving flocculus. DRPLA can be clinically diagnosed by means of clinical features, MRI findings, and neuro-otological findings. A variety of neuro-otological abnormalities may indicate a progression of the ocular disturbance and a variety of lesions.

Usui, Sadanari; Komiya, Tadatoshi

1988-06-01

363

Neurolymphomatosis on F 18 FDG PET/CT and MRI Findings: A Case Report  

Energy Technology Data Exchange (ETDEWEB)

Neurolymphomatosis is a rare manifestation of malignant lymphoma. A 74 year old man, in complete remission from diffuse large B cell lymphoma, presented with a loss of pain and temperature sensation in the left hemiface and left upper extremity, and motor weakness in the left upper and both lower extremities. Cerebrospinal fluid analysis and brain magnetic resonance imaging (MRI) findings were negative. Combined fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) revealed multiple linear hypermetabolic lesions along the mandibular branch of the left trigeminal nerve, left brachial plexus, right adrenal gland, right femoral nerve, and both sciatic nerves, which corresponded to the patient's complex neurologic symptoms. C spine and pelvic MRI revealed diffuse thickening with enhancement in the left sciatic nerve, but negative findings for other sites identified by FDG PET/CT. These findings for other sites identified by FDG PET/CT. These findings suggest that FDG PET/CT can detect peripheral nerve infiltration by malignant lymphoma earlier than MRI. Thus, if a patient with a history of lymphoma presents with neurologic symptoms, FDG PET/CT should be performed to evaluate neurolymphomatosis.

Hong, Chae Moon; Lee, Sang Woo; Lee, Hong Je; Song, Bong Il; Kim, Hae Won; Kang, Sungmin; Jeong, Shin Young; Ahn, Byeong Cheol; Lee, Jaetae; Chae, Yee Soo [Kyungpook National Univ. Hospital, Daegu (Korea, Republic of)

2011-03-15

364

Neurolymphomatosis on F 18 FDG PET/CT and MRI Findings: A Case Report  

International Nuclear Information System (INIS)

Neurolymphomatosis is a rare manifestation of malignant lymphoma. A 74 year old man, in complete remission from diffuse large B cell lymphoma, presented with a loss of pain and temperature sensation in the left hemiface and left upper extremity, and motor weakness in the left upper and both lower extremities. Cerebrospinal fluid analysis and brain magnetic resonance imaging (MRI) findings were negative. Combined fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) revealed multiple linear hypermetabolic lesions along the mandibular branch of the left trigeminal nerve, left brachial plexus, right adrenal gland, right femoral nerve, and both sciatic nerves, which corresponded to the patient's complex neurologic symptoms. C spine and pelvic MRI revealed diffuse thickening with enhancement in the left sciatic nerve, but negative findings for other sites identified by FDG PET/CT. These findings for other sites identified by FDG PET/CT. These findings suggest that FDG PET/CT can detect peripheral nerve infiltration by malignant lymphoma earlier than MRI. Thus, if a patient with a history of lymphoma presents with neurologic symptoms, FDG PET/CT should be performed to evaluate neurolymphomatosis

365

A Study of Clinical Findings and Neuroimaging Cerebral MRI and CT Scan Aspects in Wilson Disease  

Directory of Open Access Journals (Sweden)

Full Text Available Background/Objective: Wilson disease or heptolen-ticular degeneration is a genetic disorder with an autosomal recessive pattern of inheritance. It is due to an error of copper metabolism. The major presenta-tions are changes in liver, central nervous system, eyes and occasionally other organs. Early diagnosis is very important, because of its known treatment; in addition, late diagnosis is associated with irreversible changes. Our purpose was study of clinical presenta-tions and neuroimaging findings of wilson disease."nPatients and Methods: This was a descriptive study in the neurology department and MRI center of Ghaem hospital since autumn 2000 to winter 2004. This study included patients with primary presentation of neurologic and psychiatric symptoms of who were diagnosed by case finding in family. "nResults: There were 23 cases and 15 of them were men. Chief complaints were movement disorders, psychiatric disorders, speech disorders, and slowing of movement in order. Seizure, amenorrhea and eso-phageal varicose had high prevalence among our cas-es. Brain MRI disorders were seen in 95.3% of cases."nConclusion: The incidence of seizure and amenorrhea among our cases were more than previous studies. Because of high incidence of esophageal varicose in patients with primary symptoms of nervous system, we recommend that esophagoscopy for all patients should be done. This study showed no relationship between severity of symptoms and brain MRI disor-ders. MRI disorders may be seen in patients in pre-symptomatic stage. According to this, we recommend that brain MRI can be used as an Ancillary diagnostic test.

2008-01-01

366

Serial MRI findings of osteoporotic vertebral fractures in the thoracic and lumbar spine  

Energy Technology Data Exchange (ETDEWEB)

The prognosis of osteoporotic vertebral fractures in the thoracic and lumbar spine was studied by serial MRI findings. This study covered 80 vertebrae in 69 patients treated conservatively and followed-up for more than six months (23 males and 46 females, average age 70 yrs). Group A, characterized by poor diagnostic imaging, consisted of patients who had both severely collapsed vertebra which was progressive in the lateral roentgenogram and delayed improvement in MRI signal intensities. Group B, consisting of poor clinical prognosis, comprised patients with persistent back pain. The predictive factors for Group A were found to be T{sub 1}-low finding over the entire vertebra within one month after injury and fractures of Th{sub 12} or L{sub 1} vertebra. Areas of T{sub 1}-low and T{sub 2}-low intensity adjacent to the vertebral disc presented no improvement in signal intensity and often caused persistent back pain. (author)

Hamada, Yoshitaka; Henmi, Tatsuhiko; Sakamoto, Rintaro; Hiasa, Masahiko [Health Insurance Naruto Hospital, Tokushima (Japan)

1998-12-01

367

Unique MRI findings for differentiation of an early stage of hepatic alveolar echinococcosis.  

Science.gov (United States)

CT scan and ultrasonography images revealed two small uniformly low-density and hypoechoic lesions in the liver, respectively, 7?years after curative resection of rectal cancer, in a 74-year-old man. The area of the liver including the two lesions was segmentally resected. Two lesions were histopathologically confirmed as early but active stage alveolar echinococcosis (AE) caused by accidental ingestion of eggs of the fox tapeworm, Echinococcus multilocularis. This case is very unique and rare, since early stage hepatic AE cases have only accidentally been confirmed from cases in which malignant hepatic tumours were suspected, and because two independent AE lesions were detected. Abdominal MRI showed two isointense tumour lesions with small areas of high-signal intensity in their centres on T2-weighted images. MRI findings appear to reflect the macroscopic view and microscopic findings of early stage AE with active cyst in the centre of each hepatic lesion well. PMID:25697300

Aoki, Takanori; Hagiwara, Masahiro; Yabuki, Hidehiko; Ito, Akira

2015-01-01

368

MRI findings of the subacute combined degeneration of the spinal cord : a case report  

International Nuclear Information System (INIS)

Subacute combined degeneration (SCD) of the spinal cord is a neurological complication arising from vitamin B12 deficiency. Typical findings are demyelination and axonal loss of the posterior and lateral columns of the thoracic and cervical spinal cord, leading to sensory ataxia and paresthesia. Clinical and neurological features and MRI findings all contribute to the diagnosis of this entity. In the Korean medical literature, only one case of of SCD involving pre-treatment MRI has been reported. We describe one case of SCD in a post-gastrectomy patient who initially presented with progressive sensory abnormality in both upper and lower extremities and showed T2 hyperintensity in the posterior and lateral columns of the spinal cord; this diminished, with clinical improvement, after vitamin B12 therapy. Our report includes the MR images obtained during follow up. (author)

369

Neurolymphomatosis on F-18 FDG PET/CT and MRI Findings: A Case Report  

OpenAIRE

Neurolymphomatosis is a rare manifestation of malignant lymphoma. A 74-year-old man, in complete remission from diffuse large B cell lymphoma, presented with a loss of pain and temperature sensation in the left hemiface and left upper extremity, and motor weakness in the left upper and both lower extremities. Cerebrospinal fluid analysis and brain magnetic resonance imaging (MRI) findings were negative. Combined fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (...

Hong, Chae Moon; Lee, Sang-woo; Lee, Hong Je; Song, Bong Il; Kim, Hae Won; Kang, Sungmin; Jeong, Shin Young; Ahn, Byeong-cheol; Lee, Jaetae; Chae, Yee Soo

2010-01-01

370

US, CT and MRI findings in a case of diffuse lymphangiomatosis and cystic hygroma  

OpenAIRE

Lymphangiomatosis is a rare disease with multifocal lymphatic proliferation that typically occurs during childhood and involves multiple parenchymal organs including the lun