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Sample records for cine mri findings

  1. Cine MRI of hypertrophic cardiomyopathy

    International Nuclear Information System (INIS)

    Cine MRI was performed using 1.5T or 0.5T MR units in eleven patients with hypertrophic cardiomyopathy. Septal and posterior wall thickness measured by cine MRI correlated well with those obtained by ultrasonographic cardiogram. In hypertrophic obstructive cardiomyopathy, cine MRI demonstrated the site and nature of obstructive change in left ventricle. Cine MRI also showed flow void due to mitral regurgitation successfully. We considered cine MRI is useful means to evaluate the anatomical and functional findings in hypertrophic cardiomyopathy. (author)

  2. Functional cine-MRI of the pelvic floor - normal anatomy and pathologic findings

    International Nuclear Information System (INIS)

    Purpose. Functional MRI of the pelvic floor allows mapping and definition of different forms of pelvic floor dysfunction. Methods. We performed functional MRT of the pelvic floor in 39 healthy nulliparas and 324 patients. The diagnosis of a pathological organ descent was made if certain landmarks of the pelvic floor compartments descended below the pubococcygeal reference-line (PC-line). Results. If there was no organ descent below the PC-line on straining and if the pelvic floor muscles hardly changed position, a normal finding was diagnosed. 70% of organ prolapses came in the combined form. The generally gradual development of an organ descent led to a change of the main finding in 21,6%. The masking of a cystocele (48,6%) or of an enterocele (34,3%) by a rectocele was most frequent in these cases. Discussion. The use of functional MRI of the pelvic floor appears to be especially useful in young patients, in cases of divergent clinical and sonographic or radiological findings and if the presence of a predominant hernial sac with or without enterocele/rectocele is supposed. (orig.)

  3. Cine MRI of patients with cervical myelopathy

    International Nuclear Information System (INIS)

    Forty-six patients with cervical myelopathy were examined before and after surgery by cine magnetic resonance imaging (MRI). According to the occurrence site and degree of flow void, cerebrospinal fluid (CSF) flow void was classified into five: anterior type (flow void mainly in the anterior part of subarachnoid space), posterior type (mainly in the posteiror part), anteroposterior type (in the anterior and posterior parts), incomplete block type (flow void limited to the upper and lower parts of the block), and complete block type (no flow void). None of the 46 patients had normal CSF flow void on cine MRI before surgery. CSF flow void was seen in systolic phase on ECG (from 150 to 300 msec from R's wave) in all patients after spinal cord decompression. Postoperative CBF flow void types correlated well with surgical method, disease, and postoperative vertebral alignment. Postoperative outcome was the most excellent in the group of posterior type and the poorest in the group of anteroposterior type, showing a significant difference between the groups. Cine MRI is a useful noninvasive, dynamic method for assessing postoperative decompression effect. (N.K.)

  4. Cine MRI of patients with cervical myelopathy

    Energy Technology Data Exchange (ETDEWEB)

    Ukita, Yasutaka (Okayama Univ. (Japan). School of Medicine)

    1993-09-01

    Forty-six patients with cervical myelopathy were examined before and after surgery by cine magnetic resonance imaging (MRI). According to the occurrence site and degree of flow void, cerebrospinal fluid (CSF) flow void was classified into five: anterior type (flow void mainly in the anterior part of subarachnoid space), posterior type (mainly in the posteiror part), anteroposterior type (in the anterior and posterior parts), incomplete block type (flow void limited to the upper and lower parts of the block), and complete block type (no flow void). None of the 46 patients had normal CSF flow void on cine MRI before surgery. CSF flow void was seen in systolic phase on ECG (from 150 to 300 msec from R's wave) in all patients after spinal cord decompression. Postoperative CBF flow void types correlated well with surgical method, disease, and postoperative vertebral alignment. Postoperative outcome was the most excellent in the group of posterior type and the poorest in the group of anteroposterior type, showing a significant difference between the groups. Cine MRI is a useful noninvasive, dynamic method for assessing postoperative decompression effect. (N.K.).

  5. Cine-MRI swallowing evaluation after tongue reconstruction

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    Hartl, Dana M. [Department of Otolaryngology-Head and Neck Surgery, Institute Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex (France)], E-mail: dmhartl@aol.com; Kolb, Frederic; Bretagne, Evelyne [Department of Otolaryngology-Head and Neck Surgery, Institute Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex (France); Bidault, Francois; Sigal, Robert [Department of Radiology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex (France)

    2010-01-15

    Objective: To determine the feasibility of cine-MRI for non-invasive swallowing evaluation after surgery for lingual carcinoma with reconstruction using microvascular free flaps. Methods: Ten patients with stage IV carcinoma of the mobile tongue and/or tongue base treated by surgical resection and reconstruction with a free flap were evaluated after an average of 4.3 years (range: 1.5-11 years), using cine-MRI in 'single-shot fast spin echo' (SSFSE) mode. Fiberoptic laryngoscopy of swallowing was performed before MRI to detect aspiration. The tolerance and ability to complete the exam were noted. The mobilities of the oral and pharyngeal structures visualized were evaluated as normal, reduced or increased. Results: Cine-MRI was well tolerated in all cases; 'dry' swallow was performed for the 2 patients with clinical aspiration. Tongue base-pharyngeal wall contact was observed in 5 cases. An increased anterior tongue recoil, increased mandibular recoil, increased posterior oropharyngeal wall advancement and an increased laryngeal elevation were observed in 4 cases. One case of a passive 'slide' mechanism was observed. Conclusions: Cine-MRI is a safe, non-invasive technique for the evaluation of the mobility of oral and oropharyngeal structures after free-flap reconstruction of the tongue. For selected cases, it may be complementary to clinical examination for evaluation of dysphagia after surgery and free-flap reconstruction. Further technical advances will be necessary before cine-MRI can replace videofluoroscopy, however.

  6. Chest wall invasion by bronchogenic carcinoma. Evaluation with Cine-MRI

    International Nuclear Information System (INIS)

    With the view of examining possible chest wall invasion of bronchogenic carcinoma, Cine-MRI was performed on 22 such cases. These cases were suspected of having above chest wall invasion by CT and their histopathological findings were obtained in surgery. The judgment of the chest wall invasion by Cine-CT was made such that non-moving up and down of the tumor with respiration involves its invasion, moving of the tumor without any up-and-down movement suspects its invasion and moving up and down of the tumor with respiration involves no invasion. The chest wall invasion was observed in 5 of 7 cases of invasion judged by Cine-MRI. For 2 false-positive cases, the histopathological findings presumed that tumor cells disappeared from the chest wall invaded region as the result of preoperative chemotherapy. The above invasion was observed in 1 of 4 cases suspected of possible invasion. Correct diagnosis was formed of 11 cases judged invasion-free by Cine-MRI. The above results suggested Cine-MRI to be useful for diagnosis of chest wall invasion of bronchogenic carcinoma. (author)

  7. Postoperative cine-MRI for patients with cervical myelopathy

    International Nuclear Information System (INIS)

    The usefulness of cine-MRI using motion pictures was studied on 75 patients with postoperative cervical myelopathy, and morphology of cervical spine and cervical cord, postoperative MRI, and postoperative outcome were investigated. T1-weighted images by SE method and T2-weighted images by gradient field echo were obtained. Cine-MR images were classified into 5 according to the site of cerebrospinal fluid flow void and its degree (anterior type, 21; anteroposterior type, 30; posterior type, 7; incomplete block type, 15; complete block type, 2), and relationship between clinical features were studied. This method enabled dynamic noninvasive evaluation of spinal cord compression by cerebrospinal fluid flow. (S.Y.)

  8. Postoperative cine-MRI for patients with cervical myelopathy

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    Honjo, Yasuomi [Okayama Univ. (Japan). School of Medicine

    1995-07-01

    The usefulness of cine-MRI using motion pictures was studied on 75 patients with postoperative cervical myelopathy, and morphology of cervical spine and cervical cord, postoperative MRI, and postoperative outcome were investigated. T1-weighted images by SE method and T2-weighted images by gradient field echo were obtained. Cine-MR images were classified into 5 according to the site of cerebrospinal fluid flow void and its degree (anterior type, 21; anteroposterior type, 30; posterior type, 7; incomplete block type, 15; complete block type, 2), and relationship between clinical features were studied. This method enabled dynamic noninvasive evaluation of spinal cord compression by cerebrospinal fluid flow. (S.Y.).

  9. Cine MRI: a new approach to the diagnosis of scapholunate dissociation

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    Langner, I.; Eisenschenk, A. [University Medicine Greifswald, Division of Hand Surgery and Functional Microsurgery, Department of Trauma and Reconstructive Surgery, Greifswald (Germany); Fischer, S.; Langner, S. [University Medicine Greifswald, Institute for Diagnostic Radiology and Neuroradiology, Greifswald (Germany)

    2015-08-15

    To evaluate the feasibility of cine MRI for the detection of scapholunate dissociation (SLD) and to compare the sensitivity and specificity of cine MRI with those of cineradiography and arthroscopy. To evaluate feasibility, healthy subjects underwent cine MRI of the wrist. To evaluate sensitivity and specificity, patients with clinically suspected scapholunate ligament (SLL) injury after trauma to the wrist were prospectively included and underwent radiographic examination, cineradiography, and cine MRI. In 25 out of 38 patients, subsequent arthroscopy was performed. Results of cineradiography and cine MRI correlated with those of arthroscopy. Cine MRI was of diagnostic quality in all healthy subjects and patients with good interrater agreement. There was excellent correlation between cineradiography and cine MRI. Scapholunate distance differed significantly between healthy subjects and patients with scapholunate dissociation (p < 0.001), but not between imaging modalities in the patient group. Cine MRI had 85 % sensitivity and 90 % specificity for the detection of SLD. Cine MRI of the wrist is a fast and reliable technique for the detection of SLD with diagnostic accuracy comparable to cineradiography. It can be easily implemented as a routine clinical MRI examination, facilitating diagnostic workup of patients with suspected SLD while avoiding radiation exposure. (orig.)

  10. Cine MRI: a new approach to the diagnosis of scapholunate dissociation

    International Nuclear Information System (INIS)

    To evaluate the feasibility of cine MRI for the detection of scapholunate dissociation (SLD) and to compare the sensitivity and specificity of cine MRI with those of cineradiography and arthroscopy. To evaluate feasibility, healthy subjects underwent cine MRI of the wrist. To evaluate sensitivity and specificity, patients with clinically suspected scapholunate ligament (SLL) injury after trauma to the wrist were prospectively included and underwent radiographic examination, cineradiography, and cine MRI. In 25 out of 38 patients, subsequent arthroscopy was performed. Results of cineradiography and cine MRI correlated with those of arthroscopy. Cine MRI was of diagnostic quality in all healthy subjects and patients with good interrater agreement. There was excellent correlation between cineradiography and cine MRI. Scapholunate distance differed significantly between healthy subjects and patients with scapholunate dissociation (p < 0.001), but not between imaging modalities in the patient group. Cine MRI had 85 % sensitivity and 90 % specificity for the detection of SLD. Cine MRI of the wrist is a fast and reliable technique for the detection of SLD with diagnostic accuracy comparable to cineradiography. It can be easily implemented as a routine clinical MRI examination, facilitating diagnostic workup of patients with suspected SLD while avoiding radiation exposure. (orig.)

  11. Eye movement; Experimental and clinical study using cine mode MRI

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    Inatomi, Akihiro (Shiga University of Medical Science, Otsu (Japan)); Kaji, Kazutaka; Sasaki, Kenji (and others)

    1992-12-01

    This is a special lecture at the 96th Annual Congress of the Japanese Ophthalmological Society in 1992, presenting studies on eye movement using magnetic resonance imaging (MRI). Using cine mode MRI technology, two methods for producing a series of photographs have been invented: (1) the moving eye method or dynamic method in which the subjects were asked to perform 256 or 512 vertical and horizontal eye movements in synchronization with a sound trigger; and (2) the fixed eye method or static method in which the subjects were asked to gaze at individual points in a 5 to 7 point sequence as indicated by the investigator. MRI data was generated and the resulting series of photographs were observed in cine mode on a televisin monitor. Displaying the MRI-generated photographs in cine mode enables direct observation of eye movement, optic nerve and extraocular muscles within the orbit. Although the moving eye method is more accurate in its portrayal of the actual eye movement, at least 256 eye movements are required for about 5 minutes, causing physical and mental load for the subjects. The fixed eye method was thus used to examine ophthalmoplegia, including abducens palsy, oculomotor palsy, fracture of the orbital wall, foreign bodies in the orbit, Duane's syndrome, endocrine myopathy, esotropia and exotropia. This allowed the investigation of anatomical changes, such as atrophy or hypertrophy, and the functional state caused by contraction and relaxation of the extraocular muscles. Transposition of the extraocular muscles for paralytic squint was reexamined and a new surgical procedure was developed for abducens palsy. The measurement of the length, thickness and weight of the extraocular muscles from the MRI-generated photographs allowed more accurate analysis. Three dimensional reconstructive method of MRI provided a valuable tool for evaluating the orbit. (N.K.) 67 refs.

  12. The character of intracardiac hemodynamic changes in healthy volunteers studied by Cine-MRI

    International Nuclear Information System (INIS)

    15 healthy volunteers were investigated by MR to study normal intracardiac hemodynamic. Cine-MRI was performed on 1.5 T Magnetom Sp System. Regions of low signal intensity in at least cardiac chamber were found in 93 %. The most frequent finding was a linear area of signal loss along the anterior mitral leaflet during diastole (86 %). The distinction of normal areas of signal loss from pathologic is based on the extent and duration of the flow disturbance. 15 refs.; 3 figs

  13. Kinematic analysis of the knee joint by cine MRI

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    Niitsu, Mamoru; Akisada, Masayoshi; Anno, Izumi; Matsumoto, Kunihiko; Kuno, Shin-ya; Miyakawa, Shunpei (Tsukuba Univ., Ibaraki (Japan). Inst. of Clinical Medicine); Inouye, Tamon; Kose, Katsumi

    1989-08-01

    In order to obtain the MR imaging of a moving knee joint, we developed a drive system of the knee. A reciprocating reversible motor with a rope and pulleys drove a knee brace with the knee bending and extending every two seconds. Using photo sensor probe for gating cine acquisition, we got 16-time frames/cycle MR images. Such as articular cartilage, ligaments and synovial fluid, the fine components of a moving knee joint were clearly seen. In a dynamic display, these cine images demonstrated 'actual' movement of the knee joint. Moving joint fluid and defect of anterior cruciate ligament were demonstrated in the case of knee injury. These findings were not seen on static images. Cine MR imaging was also helpful for evaluating the chronic joint disease and ligament reconstruction. Through the use of the present drive system and cine acquisition, dynamic MR imaging of a moving knee joint is clearly demonstrated and it may provide useful information in the kinematic analysis of the normal and pathologic knee. (author).

  14. Kinematic analysis of the knee joint by cine MRI

    International Nuclear Information System (INIS)

    In order to obtain the MR imaging of a moving knee joint, we developed a drive system of the knee. A reciprocating reversible motor with a rope and pulleys drove a knee brace with the knee bending and extending every two seconds. Using photo sensor probe for gating cine acquisition, we got 16-time frames/cycle MR images. Such as articular cartilage, ligaments and synovial fluid, the fine components of a moving knee joint were clearly seen. In a dynamic display, these cine images demonstrated 'actual' movement of the knee joint. Moving joint fluid and defect of anterior cruciate ligament were demonstrated in the case of knee injury. These findings were not seen on static images. Cine MR imaging was also helpful for evaluating the chronic joint disease and ligament reconstruction. Through the use of the present drive system and cine acquisition, dynamic MR imaging of a moving knee joint is clearly demonstrated and it may provide useful information in the kinematic analysis of the normal and pathologic knee. (author)

  15. Functional cine-MRI of the pelvic floor - normal anatomy and pathologic findings; Funktionelle MRT des Beckenbodens: normale Anatomie und pathologische Befunde

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    Sprenger, D.; Lienemann, A.; Reiser, M. [Klinikum Grosshadern, Muenchen (Germany). Inst. fuer Radiologische Diagnostik; Anthuber, C. [Klinikum Grosshadern, Muenchen (Germany). Frauenklinik

    2000-05-01

    Purpose. Functional MRI of the pelvic floor allows mapping and definition of different forms of pelvic floor dysfunction. Methods. We performed functional MRT of the pelvic floor in 39 healthy nulliparas and 324 patients. The diagnosis of a pathological organ descent was made if certain landmarks of the pelvic floor compartments descended below the pubococcygeal reference-line (PC-line). Results. If there was no organ descent below the PC-line on straining and if the pelvic floor muscles hardly changed position, a normal finding was diagnosed. 70% of organ prolapses came in the combined form. The generally gradual development of an organ descent led to a change of the main finding in 21,6%. The masking of a cystocele (48,6%) or of an enterocele (34,3%) by a rectocele was most frequent in these cases. Discussion. The use of functional MRI of the pelvic floor appears to be especially useful in young patients, in cases of divergent clinical and sonographic or radiological findings and if the presence of a predominant hernial sac with or without enterocele/rectocele is supposed. (orig.) [German] Ziel. Die funktionelle MRT des Beckenbodens ermoeglicht die Dokumentation und Definition der verschiedenen Manifestationsformen einer Beckenbodeninsuffizienz. Methodik. Es wurde bei 39 gesunden Nulliparen und 324 Patientinnen eine funktionelle MRT des Beckenbodens durchgefuehrt. Ein pathologischer Organdeszensus wurde dokumentiert, wenn bestimmte Kennstrukturen der Beckenbodenkompartimente unterhalb der pubokokygealen Referenzlinie (PC-Linie) zu liegen kamen. Ergebnisse. Beim Normalbefund zeigt sich unter Pressen kein Deszensus der Kennstrukturen unterhalb der PC-Linie und die Beckenbodenmuskulatur veraendert ihre Position kaum. In 70% fand sich die kombinierte Form eines Organdeszensus. Die meist stufenweise Entwicklung eines Organvorfalles fuehrte bei 21.6% zu einem Wechsel des Hauptbefundes. Am haeufigsten war hierbei die Maskierung einer Zystozele (48,6%) oder einer Enterozele (34,3%) durch eine Rektozele. Diskussion. Der Einsatz der funktionellen MRT des Beckens erscheint insbesondere bei jungen Patientinnen gerechtfertigt, und in Faellen, in denen klinische und sonographische oder roentgenologische Befunde divergieren sowie bei einem vermuteten dominanten Brucksack mit oder ohne Peritoneozele, bzw. Enterozele. (orig.)

  16. A rapid-gated cine MRI technique

    International Nuclear Information System (INIS)

    There is a critical need for noninvasive evaluation of cardiac anatomy and function. Clinicians and researchers are actively using all medical imaging modalities to fill this need. The goals of the techniques vary but include visualization of the heart chambers and major vessels, measurement of myocardial thickness and mass, characterization of tissue types such as infarcted muscle, and evaluation of cardiac performance by parameters such as ejection fraction, cardiac output, and wall motion. A major goal is the noninvasive examination of coronary arteries, but no technique has reliably achieved this to date. Magnetic resonance using (MRI) has already shown great promise for cardiovascular applications. It is greatly aided by the contrast that MR can produce between flowing blood and static tissues, which thus obviates the need for administrating contrast agents. The subject of this chapter is a rapid technique that can demonstrate cardiac motion dynamics by producing images representative of a cross-section of the object throughout the cardiac cycle

  17. Research on the setting up the slice direction in cine-MRI scanning of the temporomandibular joint

    International Nuclear Information System (INIS)

    A thorough grasp of the dynamic correlation with the articular frames in the mandibular movements is useful for the diagnosis of craniomandibular disorders using the cine images in MRI examination. The present article compared cine images obtained from three directions, which were lateral pterygoid muscle, mandibular ramus, and the mandibular movements to obtain transversal images. The results obtained were as follows. The slice in the direction of the lateral pterygoid muscle was very advantageous for observation of the lateral pterygoid muscle and the maxillary artery. The slice in the direction of the mandibular movements had a slight predominance over the other two slices with respect to the dynamic grasp of positional relationships in the articular frames. These findings suggested that the slice direction suitable for scanning in cine-MRI should be selected. (author)

  18. Feasibility study to assess clinical applications of 3-T cine MRI coupled with synchronous audio recording during speech in evaluation of velopharyngeal insufficiency in children

    Energy Technology Data Exchange (ETDEWEB)

    Sagar, Pallavi; Nimkin, Katherine [Massachusetts General Hospital, Department of Radiology, Division of Pediatric Radiology, Boston, MA (United States)

    2014-08-16

    In the past decade, there has been increased utilization of magnetic resonance imaging (MRI) in evaluating and understanding velopharyngeal insufficiency (VPI). To our knowledge, none of the prior studies with MRI has simultaneously linked the audio recordings of speech during cine MRI acquisition with the corresponding images and created a video for evaluating VPI. To develop an MRI protocol with static and cine sequences during phonation to evaluate for VPI in children and compare the findings to nasopharyngoscopy and videofluoroscopy. Five children, ages 8-16 years, with known VPI, who had previously undergone nasopharyngoscopy and videofluoroscopy, were included. MRI examination was performed on a 3-T Siemens scanner. Anatomical data was obtained using an isotropic T2-weighted 3-D SPACE sequence with multiplanar reformation capability. Dynamic data was obtained using 2-D FLASH cine sequences of the airway in three imaging planes during phonation. Audio recordings were captured by a MRI compatible optical microphone. All five cases had MRI and nasopharyngoscopy and four had videofluoroscopy performed. VPI was identified by MRI in all five patients. The location and severity of the velopharyngeal gap, closure pattern, velar size and shape and levator veli palatini (LVP) muscle were identified in all patients. MRI was superior in visualizing the integrity of the LVP muscle. MRI was unable to identify hemipalatal weakness in one case. In a case of stress-induced VPI, occurring only during clarinet playing, cine MRI demonstrated discordant findings of a velopharyngeal gap during phonatory tasks but not with instrument playing. Overall, there was satisfactory correlation among MRI, nasopharyngoscopy and videofluoroscopy findings. Cine MRI of the airway during speech is a noninvasive, well-tolerated diagnostic imaging tool that has the potential to serve as a guide prior to and after surgical correction of VPI. MRI provided superior anatomical detail of the levator musculature. The creation of a video with recorded phonation allowed correlation between palatal movements and specific phonatory tasks. (orig.)

  19. Feasibility study to assess clinical applications of 3-T cine MRI coupled with synchronous audio recording during speech in evaluation of velopharyngeal insufficiency in children

    International Nuclear Information System (INIS)

    In the past decade, there has been increased utilization of magnetic resonance imaging (MRI) in evaluating and understanding velopharyngeal insufficiency (VPI). To our knowledge, none of the prior studies with MRI has simultaneously linked the audio recordings of speech during cine MRI acquisition with the corresponding images and created a video for evaluating VPI. To develop an MRI protocol with static and cine sequences during phonation to evaluate for VPI in children and compare the findings to nasopharyngoscopy and videofluoroscopy. Five children, ages 8-16 years, with known VPI, who had previously undergone nasopharyngoscopy and videofluoroscopy, were included. MRI examination was performed on a 3-T Siemens scanner. Anatomical data was obtained using an isotropic T2-weighted 3-D SPACE sequence with multiplanar reformation capability. Dynamic data was obtained using 2-D FLASH cine sequences of the airway in three imaging planes during phonation. Audio recordings were captured by a MRI compatible optical microphone. All five cases had MRI and nasopharyngoscopy and four had videofluoroscopy performed. VPI was identified by MRI in all five patients. The location and severity of the velopharyngeal gap, closure pattern, velar size and shape and levator veli palatini (LVP) muscle were identified in all patients. MRI was superior in visualizing the integrity of the LVP muscle. MRI was unable to identify hemipalatal weakness in one case. In a case of stress-induced VPI, occurring only during clarinet playing, cine MRI demonstrated discordant findings of a velopharyngeal gap during phonatory tasks but not with instrument playing. Overall, there was satisfactory correlation among MRI, nasopharyngoscopy and videofluoroscopy findings. Cine MRI of the airway during speech is a noninvasive, well-tolerated diagnostic imaging tool that has the potential to serve as a guide prior to and after surgical correction of VPI. MRI provided superior anatomical detail of the levator musculature. The creation of a video with recorded phonation allowed correlation between palatal movements and specific phonatory tasks. (orig.)

  20. Diagnosis of atrial septal defect by the combined use of spin echo method and cine MRI

    International Nuclear Information System (INIS)

    The purpose of this study is to clarify the usefulness of magnetic resonance imaging (MRI), especially of cine MRI, in the diagnosis of atrial septal defect (ASD) with or without associated anomalies. Thirty patients were studied by MRI and they consisted of 15 patients with ASD and 15 control patients with cardiac disease other than ASD. Horizontal and sagittal sections of the whole heart were obtained using spin-echo sequence (SE) and the multi-phase images of four-chamber plane were obtained using cine MRI. By SE, the defect of interatrial septum was visualized in all 15 patients with ASD, but the similar pattern was also observed in 3 of 15 control patients. By cine MRI, the shunt flow through the defect was visualized as a relatively high signal area accompanied with low signal areas on both sides. When using the criteria of the presence of both the defect and the shunt flow by cine MRI, all of the 15 patients with ASD and the 15 control patients were correctly diagnosed. On the other hand, SE was very useful in the diagnosis of the anomalies associated with ASD, especially in 3 patients with anomalous pulmonary venous drainage. Thus, the combined use of cine MRI with SE is useful for the diagnosis of ASD and its associated anomalies. (author)

  1. SU-E-J-192: Verification of 4D-MRI Internal Target Volume Using Cine MRI

    Energy Technology Data Exchange (ETDEWEB)

    Lafata, K; Czito, B; Palta, M; Bashir, M; Yin, F; Cai, J [Duke University Medical Center, Durham, NC (United States)

    2014-06-01

    Purpose: To investigate the accuracy of 4D-MRI in determining the Internal Target Volume (ITV) used in radiation oncology treatment planning of liver cancers. Cine MRI is used as the standard baseline in establishing the feasibility and accuracy of 4D-MRI tumor motion within the liver. Methods: IRB approval was obtained for this retrospective study. Analysis was performed on MR images from four patients receiving external beam radiation therapy for liver cancer at our institution. Eligible patients received both Cine and 4D-MRI scans before treatment. Cine images were acquired sagittally in real time at a slice bisecting the tumor, while 4D images were acquired volumetrically. Cine MR DICOM headers were manipulated such that each respiratory frame was assigned a unique slice location. This approach permitted the treatment planning system (Eclipse, Varian Medical Systems) to recognize a complete respiratory cycle as a “volume”, where the gross tumor was contoured temporally. Software was developed to calculate the union of all frame contours in the structure set, resulting in the corresponding plane of the ITV projecting through the middle of the tumor, defined as the Internal Target Area (ITA). This was repeated for 4D-MRI, at the corresponding slice location, allowing a direct comparison of ITAs obtained from each modality. Results: Four patients have been analyzed. ITAs contoured from 4D-MRI correlate with contours from Cine MRI. The mean error of 4D values relative to Cine values is 7.67 +/? 2.55 %. No single ITA contoured from 4D-MRI demonstrated more than 10.5 % error compared to its Cine MRI counterpart. Conclusion: Motion management is a significant aspect of treatment planning within dynamic environments such as the liver, where diaphragmatic and cardiac activity influence plan accuracy. This small pilot study suggests that 4D-MRI based ITA measurements agree with Cine MRI based measurements, an important step towards clinical implementation. NIH 1R21CA165384-01A1.

  2. Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes

    DEFF Research Database (Denmark)

    Bjerre, Troels; Crijns, Sjoerd

    2013-01-01

    The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure. The proposed strategy relies on acquiring a pre-treatment 3D breath-hold scan, extracting a 3D target template and performing template matching between this 3D template and pairs of orthogonal 2D cine-MRI planes intersecting the target motion path. For a 60 s free-breathing series of orthogonal cine-MRI planes, we demonstrate that the method was capable of accurately tracking the respiration related 3D motion of the left kidney. Quantitative evaluation of the method using a dataset designed for this purpose revealed a translational error of 1.15 mm for a translation of 39.9 mm. We have demonstrated how interleaved acquired, orthogonal cine-MRI planes can be used foronline tracking of soft-tissue target volumes.

  3. Three-dimensional cine MRI in free-breathing infants and children with congenital heart disease

    International Nuclear Information System (INIS)

    Patients with congenital heart disease frequently have complex cardiac and vascular malformations requiring detailed non-invasive diagnostic evaluation including functional parameters. To evaluate the morphological and functional information provided by a novel 3-D cine steady-state free-precession (SSFP) sequence. Twenty consecutive children (mean age 2.2 years, nine boys) were examined using a 1.5-T MR system including 2-D cine gradient-recalled-echo sequences, static 3-D SSFP and 3-D cine SSFP sequences. Measurement of ventricular structures and volumes showed close agreement between the 3-D cine SSFP sequence and the 2-D cine gradient-recalled-echo and static 3-D SSFP sequences (left ventricular volumes mean difference 1.0-1.9 ml and 8.8-11.4%, respectively; right ventricular volumes 1.7-2.1 ml and 9.9-16.9%, respectively). No systematic bias was observed. 3-D cine MRI provides anatomic as well as functional information with sufficient spatial and temporal resolution in free-breathing infants with congenital heart disease. (orig.)

  4. Evaluation of congenital heart disease by cine magnetic resonance imaging (MRI)

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    Feiglin, D.H.I.; Moodie, D.S.; O' Donnell, J.K.; Go, R.T.; Sterba, R.; MacIntyre, W.J.

    1985-05-01

    The authors studied 11 adult patients (pts) with atrial septal defect (ASD) and 4 adult pts with ventricular septal defect (VSD) using cine magnetic resonance. All studies were performed using a .6T superconducting magnet with ECG gating and electronic axial rotation when appropriate. Repeated multislice image with no change in physiologic delay of the spin echo pulse sequence, but varying the time by offsetting one slice at each imaging stage allowed for an N x N collection of data where N is the number of slices in one collection set and is equal to the number of sets collected. Algebraic manipulation of the T1 weighted images (TE=30mSec TRcine dynamic display. This technique provides multitime views of each slice and allows for greater appreciation of right atrial enlargement, right ventricular hypertrophy and dilation, and imaging of the atrial septum than does conventional MRI. Using this technique, the authors have identified both atrial and ventricular septal defects in all pts preoperatively and have noted an intact atrial septum following surgery. Standard MRI produced 4 false positive studies postoperatively because only 1 phase of the cardiac cycle was reviewed. Cine MRI allows better identification of septal defects than standard static acquisitions. The cine technique also provides better definition and delineation of right sided abnormalities which are maximized when viewed in a cardiac major axis obtained by electronic axial rotation.

  5. Compressed sensing reconstruction of cardiac cine MRI using golden angle spiral trajectories

    Science.gov (United States)

    Tolouee, Azar; Alirezaie, Javad; Babyn, Paul

    2015-11-01

    In dynamic cardiac cine Magnetic Resonance Imaging (MRI), the spatiotemporal resolution is limited by the low imaging speed. Compressed sensing (CS) theory has been applied to improve the imaging speed and thus the spatiotemporal resolution. The purpose of this paper is to improve CS reconstruction of under sampled data by exploiting spatiotemporal sparsity and efficient spiral trajectories. We extend k-t sparse algorithm to spiral trajectories to achieve high spatio temporal resolutions in cardiac cine imaging. We have exploited spatiotemporal sparsity of cardiac cine MRI by applying a 2D + time wavelet-Fourier transform. For efficient coverage of k-space, we have used a modified version of multi shot (interleaved) spirals trajectories. In order to reduce incoherent aliasing artifact, we use different random undersampling pattern for each temporal frame. Finally, we have used nonuniform fast Fourier transform (NUFFT) algorithm to reconstruct the image from the non-uniformly acquired samples. The proposed approach was tested in simulated and cardiac cine MRI data. Results show that higher acceleration factors with improved image quality can be obtained with the proposed approach in comparison to the existing state-of-the-art method. The flexibility of the introduced method should allow it to be used not only for the challenging case of cardiac imaging, but also for other patient motion where the patient moves or breathes during acquisition.

  6. Cine MRI of the temporomandibular joint in comparison to static MRI and axiography; Cine-MRT des Kiefergelenks im Vergleich zur konventionellen MRT und Achsiographie

    Energy Technology Data Exchange (ETDEWEB)

    Beer, A.; Rummeny, E.J. [Inst. fuer Roentgendiagnostik der Technischen Univ. Muenchen, Klinikum rechts der Isar (Germany); Kolk, A.; Neff, A. [Klinik und Poliklinik fuer Mund-Kiefer-Gesichtschirurgie der Technischen Univ. Muenchen, Klinikum rechts der Isar (Germany); Hof, N. [Abt. fuer Diagnostische und Interventionelle Radiologie/Nuklearmedizin, Krankenhaus Dritter Orden, Muenchen-Nymphenburg (Germany); Treumann, T. [Roentgeninstitut, Kantonshospital Luzern (Switzerland)

    2004-04-01

    Purpose: To evaluate Cine MRI (cMRI) of the temporomandibular joint in comparison to static MRI (sMRI) and axiography. Materials and Methods: In a prospective study with 57 healthy volunteers as well as 33 patients after temporomandibular joint (TMJ) surgery or with severe joint dysfunction, we measured the mobility of both condyle and disc as well as the sagittal angle of condylar inclination with sMRI and cMRI. Measurements and image analysis were performed by a radiologist and a maxillofacial surgeon in consensus. The results of axiography served as standard of reference. Result: Concerning the assessment of the discoligamentous complex, sMRI was superior to cMRI in the patient-group (sensitivity sMRI 85%, cMRI 76%), while no significant difference was found in the volunteer-group (sensitivity sMRI 97.4%, cMRI 98.3%). The results of cMRI and sMRI showed a highly significant correlation with each other, as well as with the axiographic reference tracings (r=0.90). The average mobility of the disc and condyle was 6% and 10% higher in sMRI compared to cMRI (p=0.001) and showed a slightly higher variance (0.043 vs. 0.038). Concerning the condylar inclination angle, both MRI-procedures had the best correlation (r=0.94) with each other and axiography. Conclusion: Real-time MRI of the TMJ is comparable to axiography in its accuracy and is a useful adjunct to conventional static MRI. (orig.) [German] Fragestellung: Evaluation der Cine-MRT (cMRT) des Kiefergelenks im Vergleich zur statischen MRT (sMRT) und Achsiographie. Material und Methode: Bei 57 Probanden und bei 33 Patienten nach operativem Gelenkeingriff oder mit klinischer Funktionsstoerung wurden die Kondylus- und Diskusmobilitaet sowie die horizontale Kondylenbahnneigung (HKN) in der sMRT und in der cMRT bestimmt. Die Auswertung erfolgte durch einen Radiologen und einen Mund-Kiefer-Gesichtschirurgen im Konsensus. Die Werte der Achsiographie dienten als Goldstandard. Ergebnisse: Bezueglich der Abgrenzbarkeit des diskoligamentaeren Komplexes war in der Gruppe der funktionsgestoerten Gelenke die sMRT der cMRT ueberlegen (Sensitivitaet sMRT 85%, cMRT 76%), waehrend sich bei den Probanden kein signifikanter Unterschied zeigte (Sensitivitaet sMRT 97,4%, cMRT 98,3%). Die in der sMRT und cMRT ermittelten Funktionsdaten korrelierten signifikant untereinander sowie auch mit den entsprechenden achsiographischen Referenzwerten (r=0,90). In der sMRT stellte sich die durchschnittliche Diskus- und Kondylusmobilitaet 6% bzw. 10% hoeher als in der cMRT (p=0,001) bei leicht hoeherer Varianz (v=0,043 vs 0,38) dar. Die HKN-Werte stimmten in beiden MRT-Verfahren und mit der Achsiographie mit jeweils r=0,94 am besten ueberein. Schlussfolgerung: Die Cine-MRT ist in ihrer Genauigkeit mit der Achsiographie vergleichbar und stellt als dynamische Untersuchung eine wertvolle Ergaenzung zur konventionellen statischen MRT dar. (orig.)

  7. Analysis of cerebrospinal fluid dynamics with cine MRI

    International Nuclear Information System (INIS)

    Flow velocity of cerebrospinal fluid (CSF) was analyzed at the aqueduct and the prepontine cistern with a 1.5 tesla superconductive type magnetic resonance imager (Sierra, GE Yokogawa Medical Co.). Cine mode phase contrast MR pulse sequence using peripheral gating was used to measure CSF flow direction and velocity. The CSF flow studies were done under the slice thickness of 10 mm or 2 mm. The flow patterns observed at 2 mm thin slice showed distinct to-and-fro pattern of aqueductal CSF flow and seemed to reflect the peripheral pulse rhythm. Until quite recently such invasive examination as the computed tomographic cisternography has been required to comprehend the CSF dynamics. The presented scan technique of cine mode magnetic resonance image is capable of comprehending the CSF dynamics without any invasive procedure. (author)

  8. Evaluation of the cervical carotid bifurcation using MR angiography and cine MRI

    International Nuclear Information System (INIS)

    MR angiography (MRA) can less invasively evaluate the carotid bifurcation without contrast material. Previous reports on MRA of carotid bifurcation revealed problems of overestimation and false-positive interpretation of stenosis. To clarify reasons causing overestimation and false-positive interpretation we investigated flow dynamics in the carotid bifurcation by cine MRI. Twenty-eight patients who were suspected to have stenosis of the internal carotid artery by MRA were studied. Images of the carotid bifurcation were obtained with 3-D phase contrast method by 0.5-T MR scanner. All patients were examined by IV-DSA or direct carotid angiography. Cine MRI of the carotid bifurcation was obtained with gradinet-echo sequence by 1.5-T MR scanner. Comparison of MRA and conventional angiography in evaluating degree of stenosis in the carotid bifurcation demonstrated that there were 57.1% agreement, 32.1% false-positive estimation and 10.7% overestimation. Cine MRI demonstration turbulent flow in the normal carotid bifurcation and also in the sclerotic bifurcation. Turbulence in the carotid bifurcation with severe sclerosis was greater than that in the normal carotid bifurcation. Turbulent flow could be seen extending distally to the stenotic site of the internal carotid artery. Turbulent flow in the carotid bifurcation, causing a decrease or loss in signal intensity of MRA according to the severity of the turbulence, must be a major contributing factor in false-positive estimation and overestimation of stenosis. (author)

  9. TH-A-BRF-04: Intra-Fraction Motion Characterization for Early Stage Rectal Cancer Using Cine-MRI

    International Nuclear Information System (INIS)

    Purpose: To investigate the intra-fraction motion in patients with early stage rectal cancer using cine-MRI. Methods: Sixteen patient diagnosed with early stage rectal cancer underwent 1.5 T MR imaging prior to each treatment fraction of their short course radiotherapy (n=76). During each scan session, three 2D sagittal cine-MRIs were performed: at the beginning (Start), after 9:30 minutes (Mid), and after 18 minutes (End). Each cine-MRI has a duration of one minute at 2Hz temporal resolution, resulting in a total of 3:48 hours of cine-MRI. Additionally, standard T2-weighted (T2w) imaging was performed. Clinical target volume (CTV) an tumor (GTV) were delineated on the T2w scan and transferred to the first time-point of each cine-MRI scan. Within each cine-MRI, the first frame was registered to the remaining frames of the scan, using a non-rigid B-spline registration. To investigate potential drifts, a similar registration was performed between the first frame of the Start and End scans.To evaluate the motion, the distances by which the edge pixels of the delineations move in anterior-posterior (AP) and cranial-caudal (CC) direction, were determined using the deformation field of the registrations. The distance which incorporated 95% of these edge pixels (dist95%) was determined within each cine-MRI, and between Start- End scans, respectively. Results: Within a cine-MRI, we observed an average dist95% for the CTV of 1.3mm/1.5mm (SD=0.7mm/0.6mm) and for the GTV of 1.2mm/1.5mm (SD=0.8mm/0.9mm), in respectively AP/CC. For the CTV motion between the Start and End scan, an average dist95% of 5.5mm/5.3mm (SD=3.1mm/2.5mm) was found, in respectively AP/CC. For the GTV motion, an average dist95% of 3.6mm/3.9mm (SD=2.2mm/2.5mm) was found in AP/CC, respectively. Conclusion: Although intra-fraction motion within a one minute cine-MRI is limited, substantial intra-fraction motion was observed within the 18 minute time period between the Start and End cine-MRI

  10. Evaluation of potential internal target volume of liver tumors using cine-MRI

    Energy Technology Data Exchange (ETDEWEB)

    Akino, Yuichi, E-mail: akino@radonc.med.osaka-u.ac.jp [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka 5650871, Japan and Miyakojima IGRT Clinic, Miyakojima-ku, Osaka 5340021 (Japan); Oh, Ryoong-Jin; Masai, Norihisa; Shiomi, Hiroya; Inoue, Toshihiko [Miyakojima IGRT Clinic, Miyakojima-ku, Osaka 5340021 (Japan)

    2014-11-01

    Purpose: Four-dimensional computed tomography (4DCT) is widely used for evaluating moving tumors, including lung and liver cancers. For patients with unstable respiration, however, the 4DCT may not visualize tumor motion properly. High-speed magnetic resonance imaging (MRI) sequences (cine-MRI) permit direct visualization of respiratory motion of liver tumors without considering radiation dose exposure to patients. Here, the authors demonstrated a technique for evaluating internal target volume (ITV) with consideration of respiratory variation using cine-MRI. Methods: The authors retrospectively evaluated six patients who received stereotactic body radiotherapy (SBRT) to hepatocellular carcinoma. Before acquiring planning CT, sagittal and coronal cine-MRI images were acquired for 30 s with a frame rate of 2 frames/s. The patient immobilization was conducted under the same condition as SBRT. Planning CT images were then acquired within 15 min from cine-MRI image acquisitions, followed by a 4DCT scan. To calculate tumor motion, the motion vectors between two continuous frames of cine-MRI images were calculated for each frame using the pyramidal Lucas–Kanade method. The target contour was delineated on one frame, and each vertex of the contour was shifted and copied onto the following frame using neighboring motion vectors. 3D trajectory data were generated with the centroid of the contours on sagittal and coronal images. To evaluate the accuracy of the tracking method, the motion of clearly visible blood vessel was analyzed with the motion tracking and manual detection techniques. The target volume delineated on the 50% (end-exhale) phase of 4DCT was translated with the trajectory data, and the distribution of the occupancy probability of target volume was calculated as potential ITV (ITV {sub Potential}). The concordance between ITV {sub Potential} and ITV estimated with 4DCT (ITV {sub 4DCT}) was evaluated using the Dice’s similarity coefficient (DSC). Results: The distance between blood vessel positions determined with motion tracking and manual detection was analyzed. The mean and SD of the distance were less than 0.80 and 0.52 mm, respectively. The maximum ranges of tumor motion on cine-MRI were 2.4 ± 1.4 mm (range, 1.0–5.0 mm), 4.4 ± 3.3 mm (range, 0.8–9.4 mm), and 14.7 ± 5.9 mm (range, 7.4–23.4 mm) in lateral, anterior–posterior, and superior–inferior directions, respectively. The ranges in the superior–inferior direction were larger than those estimated with 4DCT images for all patients. The volume of ITV {sub Potential} was 160.3% ± 13.5% (range, 142.0%–179.2%) of the ITV {sub 4DCT}. The maximum DSC values were observed when the cutoff value of 24.7% ± 4.0% (range, 20%–29%) was applied. Conclusions: The authors demonstrated a novel method of calculating 3D motion and ITV {sub Potential} of liver cancer using orthogonal cine-MRI. Their method achieved accurate calculation of the respiratory motion of moving structures. Individual evaluation of the ITV {sub Potential} will aid in improving respiration management and treatment planning.

  11. New developments in imaging: Sonography, cine-CT, MRI

    International Nuclear Information System (INIS)

    The book can be conveniently subdivided into three sections: the first on magnetic resonance imaging the second on cine-computed tomography and the third on advances in ultrasound (US). The MR imaging section includes two chapters: the first on indications for MR in abdominal disease (a cookbook layout of indications for MR imaging versus CT) and the second on MR imaging of the heart. There are also chapters on MR imaging and US in the pelvis, contrast agent principles, and a chapter on imaging renal tumors. The third section, on US, contains chapters on the liver and gastrointenstinal disease, interventional US sonography during neurosurgery, state-of-the-art echocardiography. Doppler flow imaging, contrast media for sonography, endometrial sonography, and high-resolution US in the first trimester. The final chapter is presented as a scientific paper rather than as a chapter in a book and has no illustrations

  12. New developments in imaging: Sonography, cine-CT, MRI

    Energy Technology Data Exchange (ETDEWEB)

    Otto, R.J.; Higgins, C.B.

    1987-01-01

    The book can be conveniently subdivided into three sections: the first on magnetic resonance imaging the second on cine-computed tomography and the third on advances in ultrasound (US). The MR imaging section includes two chapters: the first on indications for MR in abdominal disease (a cookbook layout of indications for MR imaging versus CT) and the second on MR imaging of the heart. There are also chapters on MR imaging and US in the pelvis, contrast agent principles, and a chapter on imaging renal tumors. The third section, on US, contains chapters on the liver and gastrointenstinal disease, interventional US sonography during neurosurgery, state-of-the-art echocardiography. Doppler flow imaging, contrast media for sonography, endometrial sonography, and high-resolution US in the first trimester. The final chapter is presented as a scientific paper rather than as a chapter in a book and has no illustrations.

  13. Hippocampal malrotation: MRI findings

    International Nuclear Information System (INIS)

    Purpose: To demonstrate the common features of hippocampus malrotation in patients with epilepsy by volumetric and high-resolution MRI. Material and methods: MRI study was performed in 5 patients (2 females and 3 males) ages ranged between 6-41 years (average: 25 years), all of them with epilepsy diagnosis. MRI was performed with a 1.5 T (GE Signa). The epilepsy protocol include sagittal T1, axial T1 and T2, coronal FLAIR, coronal T2 (high-resolution) and volumetric 3D SPGR IR 1.5 mm thick sequences. Results: The common features found in all patients were: a) Incomplete inversion and round configuration of the hippocampus; b) Unilateral affectation; c) Variable affectation of the hippocampus; d) Normal signal intensity; e) Modification of the inner structure of the hippocampus; f) Abnormal angularity of the collateral sulcus; g) Abnormal position and size of the fornix; h) Normal size of the temporal lobe; and i) Enlargement of the temporal horn with particular configuration. Conclusion: Hippocampus malrotation is a malformation that should be included in the differential diagnosis of the epilepsy patients. MRI provides accurate information for the diagnosis. (author)

  14. Stress cine MRI for detection of coronary artery disease

    International Nuclear Information System (INIS)

    Stress testing is the cornerstone in the diagnosis of patients with suspected coronary artery disease (CAD). Stress echocardiography has become a well-established modality for the detection of ischemia-induced wall motion abnormalities. However, display and reliable interpretation of stress echocardiography studies are user-dependent, the test reproducibility is low, and 10 to 15% of patients yield suboptimal or non-diagnostic images. Due to its high spatial and contrast resolution, MRI is known to permit an accurate determination of left ventricular function and wall thickness at rest. Early stress MRI studies provided promising results with respect to the detection of CAD. However, the clinical impact was limited due to long imaging time and problematic patient monitoring in the MRI environment. Recent technical improvements - namely ultrafast MR image acquisition - led to a significant reduction of imaging time and improved patient safety. Stress can be induced by physical exercise or pharmacologically by administration of a beta1-agonist (dobutamine) or vasodilatator (dipyridamole and adenosine). The best developed and most promising stress MRI technique is a high-dose dobutamine/atropine stress protocol (10, 20, 30, 40 ?g/kg/min; optionally 0.25-mg fractions of atropine up to maximal dose 1 mg). Severe complications (myocardial infarction, ventricular fibrillation and sustained tachycardia, cardiogenic shock) may be expected in 0.25% of patients. Currently, data of three high-dose dobutamine stress MRI studies are available, revealing a good sensitivity (83 - 87%) and specificity (83 - 86%) in the assessment of CAD. The direct comparison between echocardiography and MRI for the detection of stress-induced wall motion abnormalities yielded better results for dobutamine-MRI in terms of sensitivity (86.2% vs. 74.3%; p < 0.05) and specificity (85.7% vs. 69.8% p < 0.05) as compared to dobutamine stress echocardiography. The superior results of MRI can mainly be explained by the better image quality with sharp delineation of the endocardial and epicardial borders. Currently, stress MRI is already a realistic clinical alternative for the non-invasive assessment of CAD in patients with impaired image quality in echocardiography. (orig.)

  15. MRI findings in Hirayama disease

    Directory of Open Access Journals (Sweden)

    Raval Monali

    2010-01-01

    Full Text Available The objective of the study was to study the magnetic resonance imaging (MRI features of Hirayama disease on a 3 Tesla MRI scanner. Nine patients with clinically suspected Hirayama disease were evaluated with neutral position, flexion, contrast-enhanced MRI and fast imaging employing steady-state acquisition (FIESTA sequences. The spectrum of MRI features was evaluated and correlated with the clinical and electromyography findings. MRI findings of localized lower cervical cord atrophy (C5-C7, abnormal curvature, asymmetric cord flattening, loss of attachment of the dorsal dural sac and subjacent laminae in the neutral position, anterior displacement of the dorsal dura on flexion and a prominent epidural space were revealed in all patients on conventional MRI as well as with the dynamic 3D-FIESTA sequence. Intramedullary hyperintensity was seen in four patients on conventional MRI and on the 3D-FIESTA sequence. Flow voids were seen in four patients on conventional MRI sequences and in all patients with the 3D-FIESTA sequence. Contrast enhancement of the epidural component was noted in all the five patients with thoracic extensions. The time taken for conventional and contrast-enhanced MRI was about 30-40 min, while that for the 3D-FIESTA sequence was 6 min. Neutral and flexion position MRI and the 3D-FIESTA sequence compliment each other in displaying the spectrum of findings in Hirayama disease. A flexion study should form an essential part of the screening protocol in patients with suspected Hirayama disease. Newer sequences such as the 3D-FIESTA may help in reducing imaging time and obviating the need for contrast.

  16. MRI findings in bipartite patella

    Energy Technology Data Exchange (ETDEWEB)

    Kavanagh, Eoin C. [University of Pittsburgh Medical Centre, Department of Radiology, Pittsburgh, PA (United States); Zoga, Adam; Omar, Imran [Thomas Jefferson University Hospital, Department of Radiology, Philadelphia, PA (United States); Ford, Stephanie; Eustace, Stephen [Cappagh National Orthopaedic Hospital, Department of Radiology, Dublin (Ireland); Schweitzer, Mark [Hospital for Joint Disease, Orthopedic Institute, Department of Radiology, New York, NY (United States)

    2007-03-15

    Bipartite patella is a known cause of anterior knee pain. Our purpose was to detail the magnetic resonance imaging (MRI) features of bipartite patella in a retrospective cohort of patients imaged at our institution. MRI exams from 53 patients with findings of bipartite patella were evaluated to assess for the presence of bone marrow edema within the bipartite fragment and for the presence of abnormal signal across the synchondrosis or pseudarthrosis. Any other significant knee pathology seen at MRI was also recorded. We also reviewed 400 consecutive knee MRI studies to determine the MRI prevalence of bipartite patella. Of the 53 patients with bipartite patella 40 (75%) were male; 35 (66%) had edema within the bipartite fragment. Of the 18 with no edema an alternative explanation for knee pain was found in 13 (72%). Edema within the bipartite fragment was the sole finding in 26 of 53 (49%) patients. Bipartite patella was seen in 3 (0.7%) of 400 patients. In patients with bipartite patella at knee MRI, bone marrow edema within the bipartite fragment was the sole finding on knee MRI in almost half of the patients in our series. (orig.)

  17. Assessment of left atrial volume by Gd-DTPA-enhanced ultrafast cine MRI. Hemodynamic assessment in various diseases

    Energy Technology Data Exchange (ETDEWEB)

    Matsumura, Kentaro; Nakase, Emiko; Hashi, Masashi; Kawai, Ichiro; Saito, Takayuki; Haiyama, Tohru; Kikkawa, Nobutada [Kyoto Minami Hospital, Nishishichijyo (Japan)

    1995-10-01

    To assess the validity of contrast-enhanced breath-hold ultrafast cine MR imaging in left atrial (LA) volumes (LA max.I: maximal volume index of LA/LA min.I: minimal volume index of LA) and LA-volume curve, this method was compared with intravenous digital subtraction left atrial angiography (DSA) in serial 26 patients. The pulse sequence of ultrafast cine MRI were TR 8 ms, TE 3.2 ms, matrix 128 x 96 and NEX 1. The contrast-enhanced ultrafast cine MRI was shown to provide accurate left atrial images with higher success rate (88.9% in horizontal long axis view and 86.9% in vertical long axis view) in serial 891 cases. Comparison with LA volumes showed a high correlation (LA max.I: r=0.934, p<0.001/LA min.I: r=0941, p<0.001) between ultrafast cine MRI and DSA, but LA volumes were underestimated in MRI. The left atrial volumes were calculated with biplane modified Simpson`s rule method on horizontal and vertical long axis sections. Normal LA volumes obtained by ultrafast cine MRI were 30{+-}5 ml/m{sup 2} in maximum and 17{+-}5 ml/m{sup 2} in minimum. In patients with hypertension, old myocardial infarction, mitral valve diseases, dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy, LA-volumes were significantly increased. The LA-volumes at the beginning of left atrial active contraction were significantly correlated with LA-volume of active contraction. However, in patients with DCM, these statistical correlation were not demonstrated. In patients with DCM, preload of LA were increased, but LA-volumes of active contraction were not increased. For this reason, the afterload mismatch of LA was suspected in DCM. In conclusion, the contrast-enhanced ultrafast cine MRI is useful for determining LA volumes and LA volume curves. (author).

  18. Brain venous pathologies: MRI findings

    International Nuclear Information System (INIS)

    Purpose: To describe MRI findings of the different brain venous pathologies. Material and Methods: Between January 2002 and March 2004, 18 patients were studied 10 males and 8 females between 6 and 63 years old; with different brain venous pathologies. In all cases brain MRI were performed including morphological sequences with and without gadolinium injection and angiographic venous sequences. Results: 10 venous occlusions were found, 6 venous angiomas, and 2 presented varices secondary to arteriovenous dural fistula. Conclusion: Brain venous pathologies can appear in many different clinical contexts, with different prognosis and treatment. In all the cases brain MRI was the best imaging study to disclose typical morphologic abnormalities. (author)

  19. MRI findings of intraocular diseases

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, Makoto; Nagai, Haruhiko; Ueno, Tetsuji; Igarashi, Yasuo (Sapporo Medical Coll. (Japan)); Narazaki, Yoshikazu; Takeda, Akira

    1989-06-01

    MRI findings of intra-ocular lesion were studied on seven cases : two cases of choroidal malignant melanoma, one case of choroidal tumor, two cases of retinal detachment with vitreous hemorrhage, and two cases of choroidal detachment. Intraocular lesions were clearly visualized by T{sub 1} weighted MRI which was of great benefit in visualizing morphological changes. T{sub 2} weighted images could not visualize morphological changes very well, but had some merits in differentiating the ocular pathology. MRI was a very useful examination for intra-ocular lesions. (author).

  20. MRI findings of intraocular diseases

    International Nuclear Information System (INIS)

    MRI findings of intra-ocular lesion were studied on seven cases : two cases of choroidal malignant melanoma, one case of choroidal tumor, two cases of retinal detachment with vitreous hemorrhage, and two cases of choroidal detachment. Intraocular lesions were clearly visualized by T1 weighted MRI which was of great benefit in visualizing morphological changes. T2 weighted images could not visualize morphological changes very well, but had some merits in differentiating the ocular pathology. MRI was a very useful examination for intra-ocular lesions. (author)

  1. Evaluation of aortic regurgitation using cine magnetic resonance imaging

    International Nuclear Information System (INIS)

    Cine magnetic resonance imaging (MRI) was used to assess aortic regurgitation (AR) in 13 patients with valvular disease and 3 normal subjects, and the results were compared to color Doppler flow mapping findings. AR produced a signal void in the left ventricle during the diastolic phase in all patients by MRI. There were no false positive or negative results compared with echocardiographic findings. Visual grading of cine MRI gave results similar to color flow Doppler echocardiography (88%). The distance and the area of aortic regurgitation using MRI correlated well with color Doppler flow mapping (r=0.82 and 0.88). However, measurements of distance and area by color flow Doppler tended to be larger than those by cine MRI. With current techniques echocardiography may overestimate the severity of AR as compared with cine MRI. In addition, MRI gives clinically useful information in patients in whom transthoracic Doppler echocardiography is not adequate. (author)

  2. Frequency analyses of CSF flow on cine MRI in normal pressure hydrocephalus

    Energy Technology Data Exchange (ETDEWEB)

    Miyati, Tosiaki; Kasuga, Toshio; Koshida, Kichiro; Sanada, Shigeru; Onoguchi, Masahisa [Department of Radiological Technology, School of Health Sciences, Faculty of Medicine, Kanazawa University, 5-11-80, Kodatsuno, Kanazawa, Ishikawa 920-0942 (Japan); Mase, Mitsuhito; Yamada, Kazuo [Department of Neurosurgery, Nagoya City University Medical School, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi 467-8602 (Japan); Banno, Tatsuo [Department of Central Radiology, Nagoya City University Hospital, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi 467-8602 (Japan); Fujita, Hiroshi [Department of Information Science, Faculty of Engineering, Gifu University, Yanagido 1-1, Gifu 501-1193 (Japan)

    2003-05-01

    Our objective was to clarify intracranial cerebrospinal fluid (CSF) flow dynamics in normal-pressure hydrocephalus (NPH). Frequency analyses of CSF flow measured with phase-contrast cine MRI were performed. The CSF flow spectra in the aqueduct were determined in patients (n=51) with NPH, brain atrophy or asymptomatic ventricular dilation (VD), and in healthy volunteers (control group; n=25). The changes in CSF flow spectra were also analyzed after intravenous injection of acetazolamide. Moreover, a phase transfer function (PTF) calculated from the spectra of the driving vascular pulsation and CSF flow in the aqueduct were assessed. These values were compared with the pressure volume response (PVR). The amplitude in the NPH group was significantly larger than that in the VD or control group because of a decrease in compliance. The phase in the NPH group was significantly different from that in either the VD or the control group, but no difference was found between the VD and control groups. The amplitude increased in all groups after acetazolamide injection. The PTF in the NPH group was significantly larger than in the control group, and a positive correlation was noted between PTF and PVR. Frequency analyses of CSF flow measured by cine MRI make it possible to noninvasively obtain a more detailed picture of the pathophysiology of NPH. (orig.)

  3. Cine-MRI tagging for assessment of ventricular wall motion in patients under maintenance hemodialysis

    International Nuclear Information System (INIS)

    We evaluated the ventricular wall shortening velocity of patients with volume overload using cine-MRI tagging. The subjects were 12 healthy volunteers and 10 patients under maintenance hemodialysis. Three linear tags (basal, mid-ventricular, and apical) were set up in the 4-chamber view and ? distance/Ejection time (?d/ET) was calculated before and after hemodialysis. Before hemodialysis, ?d/ET was significantly greater at the basal level than after hemodialysis (right ventricular wall : 64.7±14.3 vs 59.1±15.4 mm/s, P<0.05, interventricular septum : 36.3±6.9 vs 32.4±7.6 mm/s, P<0.05, left ventricular free wall : 40.5±6.8 vs 36.1±8.2 mm/s, P<0.05). Thus, volume overload increased ?d/ET of the normal heart. We concluded that cine-MRI tagging could quantitatively evaluate right and left ventricular wall motion. (author)

  4. Tissue-Point Motion Tracking in the Tongue from Cine MRI and Tagged MRI

    Science.gov (United States)

    Woo, Jonghye; Stone, Maureen; Suo, Yuanming; Murano, Emi Z.; Prince, Jerry L.

    2014-01-01

    Purpose: Accurate tissue motion tracking within the tongue can help professionals diagnose and treat vocal tract--related disorders, evaluate speech quality before and after surgery, and conduct various scientific studies. The authors compared tissue tracking results from 4 widely used deformable registration (DR) methods applied to cine magnetic…

  5. MRI findings in cranial eumycetoma

    Directory of Open Access Journals (Sweden)

    Munawwar Ahmed

    2011-01-01

    Full Text Available Cranial eumycetoma (CE due to direct inoculation of Madurella grisea into the scalp is extremely rare. We describe a case of CE caused by direct inoculation of M. grisea with the characteristic MRI findings of the "dot-in-circle" sign and a conglomeration of multiple, extremely hypointense "dots."

  6. Cine MRI of the ascending aorta in the elderly with respect to the flow signal void and aortic valve morphology

    International Nuclear Information System (INIS)

    Cine flow MRI was performed on a 1.5 Tesla system to observe signal intensity of blood flow within the ascending aorta in the elderly who had no aortic stenosis and to determine frequency of the flow signal void. Coronal and sagittal imaging planes of the ascending aorta were obtained in 27 aged patients with no known cardiac diseases (14 men and 13 women, mean age of 76) and 7 young volunteers (7 men, mean age of 24), utilizing ECG-gating, GRASS (gradient-recalled acquisition in steady state), and a flow compensation sequence. The young volunteers presented little or no signal void within the ascending aorta. In 26 (96%) of the 27 aged patients, on the other hand, signal void was demonstrated in the blood flow distal to the aortic valve during systole. The maximum length of the signal void that was measured at 318?632 msec after the R wave of ECG ranged from 33 to 97 mm. Conventional and Doppler echocardiography was used to evaluate motion and morphology of the aortic valve in 19 of the 27 aged patients. Eighteen of these 19 subjects had aortic signal void on cine MRI. Echocardiography showed sclerotic changes of the aortic valve (i.e., increased echogenicity of the cusps and/or commissure fusion) in 10 (53%) of the 19 subjects. The mean maximum length of the signal void in the 10 patients with aortic valve sclerosis was significantly greater than that in the 9 patients with echocardiographically normal valve (68 vs.45 mm, p<0.01). These results suggest that signal void of blood flow in the ascending aorta, which is recognized as one of the characteristic findings in patients with aortic stenosis, is not a specific feature for this disease but rather a commom one in the elderly particularly those with sclerotic changes of the aortic valve. However, the length of the signal void may distinguish between nonstenotic and stenotic aortic valves. (author)

  7. Comparison of delayed enhanced cine MRI, single photon emission computed tomography and echocardiography for the detection of viable myocardium

    International Nuclear Information System (INIS)

    Objective: To evaluate the accuracy of delayed enhanced cardiac MRI(DE-MRI), nitrate stress 99Tcm-MIBI imaging (N-SPECT) and low-dose dobutamine stress echocardiography (LDDSE) for the detection of viable myocardium. Methods: Cardiac rest cine MRI(cine-MRI), DE-URI, N-SPECT and LDDSE were performed in 32 patients within one week after onset of acute myocardial infarction and undertaking percutaneous coronary intervention (PCI) thereafter. Second cine-MRI was performed 6- 11 months after PCI. A 16-segment model was adopted for the image analysis. Wall motion improvement after PCI was considered as a myocardial viability. The sensitivity, specificity and accuracy of three methods for the detection of viable segments were compared dy t and ?2 test. Results: The sensitivity, specificity and accuracy of DE-MRI were 76.7% (79/103), 83.8% (88/105)and 80.3% (167/208), respectively. The sensitivity, specificity and accuracy of N-SPECT were 75.9% (82/108), 65.2% (60/92) and 71.0% (142/200), respectively. The specificity and accuracy of N-SPECT were significantly lower than that of DE- MRI(P<0.01). The sensitivity, specificity and accuracy of LDDSE were 70.1% (47/67), 70.4% (50/71) and 70. 3% (97/138), respectively. The sensitivity of LDDSE was comparable to that of DE-MRI and the specificity and accuracy of LDDSE were significantly lower than that of DE-MRI (P<0.05). Conclusion: DE-MRI with high specificity and accuracy, potentially, is a valuable imaging method for the detection of viable myocardium. (authors)

  8. Evaluating the effect of rectal distension and rectal movement on prostate gland position using cine MRI

    International Nuclear Information System (INIS)

    Purpose: To evaluate the dynamic interrelationship between rectal distension and rectal movements, and to determine the effect of rectal movement on the position of the prostatic gland using cine magnetic resonance imaging (MRI). Methods and Materials: Fifty-five patients with biopsy-proven or suspected prostate cancer were examined in the axial plane using repeated spoiled gradient-echo sequences every 10 seconds for 7 minutes. Twenty-four patients received bowel relaxants before imaging. Images were analyzed for the degree of rectal distension, for the incidence, magnitude, and number of rectal and prostate movements. Results: Rectal movements were seen in 28 (51%) patients overall, in 10 (42%) of those receiving bowel relaxants and in 18 (58%) not receiving bowel relaxants. The incidence of rectal movements correlated with the degree of rectal distension (p = 0.0005), but the magnitude of rectal movements did not correlate with the degree of rectal distension. Eighty-six rectal movements resulting in 33 anterior-posterior (AP) prostate movements were seen. The magnitude of rectal movements correlated well with degree of prostate movements (p < 0.001). Prostate movements in the AP direction were seen in 16 (29%) patients, and in 9 (16%) patients the movement was greater than 5 mm. The median prostate AP displacement was anterior by 4.2 (-5 to +14 mm). Conclusions: Cine MRI is able to demonstrate near real time rectal and associated prostate movements. Rectal movements are related to rectal distension and result in significant displacements of the prostate gland over a time period similar to that used for daily fractionated radiotherapy treatments. Delivery of radiotherapy needs to take into account these organ movements

  9. MRI in insulinomas; Preliminary findings

    Energy Technology Data Exchange (ETDEWEB)

    Liessi, Guido (Ospedale Civile, Castelfranco Veneto (Italy). Servizio di Radiologia); Pasquali, Claudio; Alfano D' Andrea, Alfonso; Pedrazzoli, Sergio (Padova Universita, I Cattedra di: Patologia Speciale Chirurgica (Italy). Istituto di Clinica Chirurgica); Scandellari, Cesare (Padova Universita, Cattedra di Medicina Interna V (Italy). Istituto di Semeiotica Medica)

    After establishing the diagnosis of an insulinoma, most surgeons prefer preoperative localization. Selective arteriography is usually considered the gold standard for this purpose. Recently, computed tomography (CT) and preoperative US have contended the role to angiography. MRI has been used in few cases of endocrine pancreatic tumors, and its role in this particular field has to be defined. Between November 1988-September 1990 7 adult patients who had undergone surgery were evaluated. Eight tumors were resected in 6 patients who were cured; in an 18-year-old woman surgical treatment was unsuccessful. Arterio-graphy, CT, preoperative US, MRI and intraoperative US detected 2, 6, 6, 5 and 6 tumors respectively. Two insulinomas (0.2 and 0.7 cm) were found at histologic examination in resected specimen. The ability of intra-operative US and careful surgical exploration to resolve more than 90 percent of cases makes the preoperative use of arteriography and CT questionable value. If further experience confirms these findings, US and MRI may suffice. (author). 13 refs.; 3 figs.; 1 tab.

  10. Internal margin assessment using cine MRI analysis of deglutition in head and neck cancer radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Paulson, Eric S.; Bradley, Julie A.; Wang Dian; Ahunbay, Ergun E.; Schultz, Christoper; Li, X. Allen [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 (United States)

    2011-04-15

    Purpose: Intensity-modulated radiation therapy (IMRT) is a promising treatment modality for patients with head and neck cancer (HNC). The dose distributions from IMRT are static and, thus, are unable to account for variations and/or uncertainties in the relationship between the patient (region being treated) and the beam. Organ motion comprises one such source of this uncertainty, introduced by physiological variation in the position, size, and shape of organs during treatment. In the head and neck, the predominant source of this variation arises from deglutition (swallowing). The purpose of this study was to investigate whether cinematographic MRI (cine MRI) could be used to determine asymmetric (nonuniform) internal margin (IM) components of tumor planning target volumes based on the actual deglutition-induced tumor displacement. Methods: Five head and neck cancer patients were set up in treatment position on a 3 T MRI scanner. Two time series of single-slice, sagittal, cine images were acquired using a 2D FLASH sequence. The first time series was a 12.8 min scan designed to capture the frequency and duration of deglutition in the treatment position. The second time series was a short, 15 s scan designed to capture the displacement of deglutition in the treatment position. Deglutition frequency and mean swallow duration were estimated from the long time series acquisition. Swallowing and resting (nonswallowing) events were identified on the short time series acquisition and displacement was estimated based on contours of gross tumor volume (GTV) generated at each time point of a particular event. A simple linear relationship was derived to estimate 1D asymmetric IMs in the presence of resting- and deglutition-induced displacement. Results: Deglutition was nonperiodic, with frequency and duration ranging from 2.89-24.18 mHz and from 3.86 to 6.10 s, respectively. The deglutition frequency and mean duration were found to vary among patients. Deglutition-induced maximal GTV displacements ranged from 0.00 to 28.36 mm with mean and standard deviation of 4.72{+-}3.18, 3.70{+-}2.81, 2.75{+-}5.24, and 10.40{+-}10.76 mm in the A, P, I, and S directions, respectively. Resting-induced maximal GTV displacement ranged from 0.00 to 5.59 mm with mean and standard deviation of 3.01{+-}1.80, 1.25{+-}1.10, 3.23+2.20, and 2.47{+-}1.11 mm in the A, P, I, and S directions, respectively. For both resting and swallowing states, displacement along the S-I direction dominated displacement along the A-P direction. The calculated IMs were dependent on deglutition frequency, ranging from 3.28-4.37 mm for the lowest deglutition frequency patient to 3.76-6.43 mm for the highest deglutition frequency patient. A statistically significant difference was detected between IMs calculated for P and S directions (p=0.0018). Conclusions: Cine MRI is able to capture tumor motion during deglutition. Swallowing events can be demarcated by MR signal intensity changes caused by anatomy containing fully relaxed spins that move medially into the imaging plane during deglutition. Deglutition is nonperiodic and results in dynamic changes in the tumor position. Deglutition-induced displacements are larger and more variable than resting displacements. The nonzero mean maximum resting displacement indicates that some tumor motion occurs even when the patient is not swallowing. Asymmetric IMs, derived from deglutition frequency, duration, and directional displacement, should be employed to account for tumor motion in HNC RT.

  11. Joint multi-object registration and segmentation of left and right cardiac ventricles in 4D cine MRI

    Science.gov (United States)

    Ehrhardt, Jan; Kepp, Timo; Schmidt-Richberg, Alexander; Handels, Heinz

    2014-03-01

    The diagnosis of cardiac function based on cine MRI requires the segmentation of cardiac structures in the images, but the problem of automatic cardiac segmentation is still open, due to the imaging characteristics of cardiac MR images and the anatomical variability of the heart. In this paper, we present a variational framework for joint segmentation and registration of multiple structures of the heart. To enable the simultaneous segmentation and registration of multiple objects, a shape prior term is introduced into a region competition approach for multi-object level set segmentation. The proposed algorithm is applied for simultaneous segmentation of the myocardium as well as the left and right ventricular blood pool in short axis cine MRI images. Two experiments are performed: first, intra-patient 4D segmentation with a given initial segmentation for one time-point in a 4D sequence, and second, a multi-atlas segmentation strategy is applied to unseen patient data. Evaluation of segmentation accuracy is done by overlap coefficients and surface distances. An evaluation based on clinical 4D cine MRI images of 25 patients shows the benefit of the combined approach compared to sole registration and sole segmentation.

  12. Frequency analysis of CSF flow on cine-MRI in normal pressure hydrocephalus

    Energy Technology Data Exchange (ETDEWEB)

    Miyati, Tosiaki; Kasuga, Toshio; Imai, Hiroshi [Kanazawa Univ. (Japan). School of Medicine; Fujita, Hiroshi; Mase, Mitsuhito; Itikawa, Katuhiro

    2001-09-01

    To clarify the flow dynamics of intracranial cerebrospinal fluid (CSF) in normal pressure hydrocephalus (NPH), frequency analyses of CSF flow measured with an ECG-gated phase contrast cine magnetic resonance imaging (MRI) were performed. The amplitude and phase in the CSF flow spectra in the aqueduct were determined in patients with NPH after a subarachnoid hemorrhage (SAH-NPH group, n=26), an idiopathic NPH (I-NPH group, n=4), an asymptomatic ventricular dilation or a brain atrophy (VD group, n=21), and in healthy volunteers (control group, n=25). The changes of CSF flow spectra were also analyzed 5 and 15 minutes after an intravenous injection of acetazolamide. Moreover, a phase transfer function (PTF) calculated from the spectra of the driving vascular pulsation and CSF flow in the aqueduct were assessed in patients with SAH-NPH and control groups before and after acetazolamide injection. There values were compared with the pressure volume response (PVR). The amplitude of the 1st-3rd harmonics in the SAH-NPH or I-NPH group was significantly larger than in the control or VD group because of a decrease in compliance (increase in PVR). The phase of the 1st harmonic in the SAH-NPH group was significantly different from that in the control or VD group, but no difference was found between the control and VD groups. The amplitude of the 0-3rd harmonics increased, and the phase of the 1st harmonic changed in all groups after an acetazolamide injection. An evaluation of the time course of the direct current of CSF flow provided further information about the compensatory faculty of the cerebrospinal cavity. A PTF of the 1st harmonic in the SAH-NPH group was significantly larger than in the control group, and a positive correlation was noted between PTF of the 1st harmonic and PVR. In conclusion, frequency analyses of CSF flow measured by cine-MRI make it possible to obtain noninvasively a more detailed picture of the pathophysiology of NPH and of changes in intracranial conditions. (author)

  13. Pineal cysts: an incidental MRI finding?

    OpenAIRE

    Di Costanzo, A; Tedeschi, G; Di Salle, F; Golia, F; Morrone, R.; Bonavita, V

    1993-01-01

    The incidence of pineal cysts (PC) in "standard" MRI was reviewed. Seven cases of PC were found from 400 consecutive MRI examinations. PC did not produce clinically relevant symptoms in any of the patients. Our data, as well as those emerging from a critical review of the literature, suggest that PC are often asymptomatic and represent an incidental MRI finding.

  14. MRI Findings in Knee Trauma

    OpenAIRE

    Maryam Barzin; Iradj Maleki

    2009-01-01

      "nMRI is the examination of choice for the evaluation of knee trauma. The use of a surface coil and thin-section high resolution scanning techniques in multiple planes has enhanced the depiction of structural details. This article reviews the MRI appearance of the normal knee anatomy and the role of MRI in the evaluation of knee trauma. The suggested protocol for the imaging of traumatic knee is coronal, sagittal and axial fast spin echo. At least one fat suppression sequence ...

  15. MRI findings of bone tumor

    Energy Technology Data Exchange (ETDEWEB)

    Hamanaka, Hideaki; Kashiwagi, Teruyuki; Chosa, Etuo; Kuwahara, Shigeru; Tajima, Naoya [Miyazaki Medical Coll., Kiyotake (Japan)

    1996-09-01

    To investigate the usefulness of magnetic resonance imaging, MRI, of bone tumors, we retrospectively reviewed 32 MRI examination already diagnosed pathologically. Subjects included 18 males and 14 females, ranging in age from 5 to 63 years, with a means of 29.3 years. These included 25 benign bone tumors and 7 malignant bone tumors. The accuracy of a qualitative diagnosis was observed in giant cell tumor, osteoid osteoma, fibrous dysplasia and ossifying fibroma. In malignant bone tumors, it is difficult to accurately diagnose with MRI, although MRI was useful in showing interaction of the tumor and host tissue, extension, edema and reactive zone. (author)

  16. Accuracy of left ventricular ejection fraction estimation by gated Tc-99m sestamibi SPECT: Comparison with breath hold Cine MRI

    International Nuclear Information System (INIS)

    Full text: Left Ventricular Ejection Fraction (LVEF) is one of the most important functional parameters in clinical cardiology. Due to the high temporal and spatial resolution of Breath Hold Cine MRI (MRI), this technique is considered to be able to accurately estimate Left Ventricular volumes and hence LVEF. Recently, LVEF has been measured using Gated Tc-99m Sestamibi SPECT (GSSPECT) and a validation study comparing LVEF calculated by GSSPECT and MRI was performed. Over a four month period, 14 patients had both GSSPECT and MRI within a stable 7 day period. All patients were being investigated for CAD and the GSSPECT was performed as part of the routine myocardial perfusion imaging. GSSPECT was performed at rest one hour after peak exercise injection of Tc-99m Sestamibi (mean dose 1000 MBq, range 800- 1100 MBq) with imaging performed on Picker 1000 gamma camera or 3000 using standard 8 interval acquisition. All patients were analysed with the automated Picker QGS package. MRI was performed on a 1.5 T MRI( GE Signa Advantage) using a previously described breath hold Cine technique with data being acquired in the cardiac short axis. The entire LV was imaged with 10 cm contiguous short axis slices being acquired with 11-16 frames per slice, depending on heart rate. A semi automated volumetric image analysis program was used to estimate LV volumes using Simpson's rule. The range of LVEF was from 30% to 70%. Linear regression analysis demonstrated excellent agreement for LVEF calculated by GSSPECT and MRI (y= -5.4 + 0.97 x, r=0.90). Automated estimation of LVEF using GSSPECT correlates well with LVEF estimations using MRI and can accurately estimate LVEF in routine clinical practice

  17. Quantification of lung tumor rotation with automated landmark extraction using orthogonal cine MRI images

    Science.gov (United States)

    Paganelli, Chiara; Lee, Danny; Greer, Peter B.; Baroni, Guido; Riboldi, Marco; Keall, Paul

    2015-09-01

    The quantification of tumor motion in sites affected by respiratory motion is of primary importance to improve treatment accuracy. To account for motion, different studies analyzed the translational component only, without focusing on the rotational component, which was quantified in a few studies on the prostate with implanted markers. The aim of our study was to propose a tool able to quantify lung tumor rotation without the use of internal markers, thus providing accurate motion detection close to critical structures such as the heart or liver. Specifically, we propose the use of an automatic feature extraction method in combination with the acquisition of fast orthogonal cine MRI images of nine lung patients. As a preliminary test, we evaluated the performance of the feature extraction method by applying it on regions of interest around (i) the diaphragm and (ii) the tumor and comparing the estimated motion with that obtained by (i) the extraction of the diaphragm profile and (ii) the segmentation of the tumor, respectively. The results confirmed the capability of the proposed method in quantifying tumor motion. Then, a point-based rigid registration was applied to the extracted tumor features between all frames to account for rotation. The median lung rotation values were??-0.6???±???2.3° and??-1.5???±???2.7° in the sagittal and coronal planes respectively, confirming the need to account for tumor rotation along with translation to improve radiotherapy treatment.

  18. MRI findings of juvenile psoriatic arthritis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Edward Y.; Kleinman, Paul K. [Harvard Medical School, Department of Radiology, Boston, MA (United States); Children' s Hospital Boston, MA (United States); Sundel, Robert P.; Kim, Susan [Harvard Medical School, Rheumatology Program, Division of Immunology and the Department of Pediatrics, Boston, MA (United States); Children' s Hospital Boston, MA (United States); Zurakowski, David [Harvard Medical School, Department of Radiology, Boston, MA (United States); Harvard Medical School, Department of Orthopaedic Surgery, Boston, MA (United States); Children' s Hospital Boston, MA (United States)

    2008-11-15

    The aim of this study was to describe the magnetic resonance imaging (MRI) features of juvenile psoriatic arthritis (JpsA) in children in order to facilitate early diagnosis and proper management. Two pediatric radiologists retrospectively reviewed in consensus a total of 37 abnormal MRI examinations from 31 pediatric patients (nine boys, 22 girls; age range 1-17 years; mean age 9.4 years) who had a definite diagnosis of JpsA and underwent MRI. Each MRI was evaluated for synovium abnormality (thickening and enhancement), joint effusion (small, moderate, and large), bone marrow abnormality (edema, enhancement, and location of abnormality), soft tissue abnormality (edema, enhancement, atrophy, and fatty infiltration), tendon abnormality (thickening, edema, tendon sheath fluid, and enhancement), and articular abnormality (joint space narrowing and erosion). The distribution of abnormal MRI findings among the six categories for the 37 MRI examinations was evaluated. The number of abnormal MRI findings for each MRI examination was assessed. Age at MRI examination and all six categories of abnormal MRI findings according to gender were evaluated. There were a total 96 abnormal MRI findings noted on 37 abnormal MRI examinations from 31 pediatric patients. The 37 abnormal MRI examinations included MRI of the hand (n=8), knee (n = 8), ankle (n = 5), pelvis (n = 5), temporomandibular joint (n = 4), wrist (n = 3), foot (n = 2), elbow (n = 1), and shoulder (n = 1). Twenty-eight diffuse synovial thickening and/or enhancement were the most common MRI abnormality (29.2%). Joint effusion comprised 22 abnormal MRI findings (22.9%). There were 16 abnormal MRI bone marrow edema and/or enhancement findings (16.7%), and in seven (7.3%) the edema involved non-articular sites. Soft tissue abnormality manifested as edema and/or enhancement constituted 14 abnormal MRI findings (14.5%). There were ten MRI abnormalities (10.4%) involving tendons. Articular abnormality seen as joint space narrowing and/or bone erosion comprised six abnormal MRI findings (6.2%). Most MRI examinations had more than one abnormal finding (84%). Age at which MRI examinations were performed was not significantly different between boys and girls. All six categories of abnormal MRI findings were not significantly different between boys and girls. Children with JpsA typically present with more than one abnormal finding on their MRI studies. While synovial abnormality is the most common MR finding in children with JpsA, multi-focal bone marrow edema and enhancement at both articular and non-articular sites are also notable findings in children with JpsA. The rate of articular abnormality is much lower in children with JpsA in comparison to adults with psoriatic arthritis. Our findings suggest that MRI can play a useful role in the diagnosis and ongoing assessment of this uncommon, though important, pediatric rheumatologic disorder. (orig.)

  19. Detection of viable myocardium by low dose dobutamine cine MRI: experimental study in pigs

    International Nuclear Information System (INIS)

    Objective: To evaluate the diagnostic value of dobutamine stress magnetic resonance imaging (MR) for myocardial viability. Methods: Mini swine (n = 10) underwent left ventriculography and coronary angiography, followed by stenosis of the left circumflex coronary artery (LCX) using aneroid constrictor. More than 1 month later left ventriculography and coronary angiography were performed again, followed by cine-MR at rest and during stress with incremental dose of dobutamine 5-20 ?g · kg-1 · min-1. Traditional and/or breath-hold cine-MR were used to evaluate regional left ventricular wall motion, corresponding to basal, mid ventricular and apical short-axis tomograms. Regional wall motion score index (WMSI) was calculated. Mini swine were finally sacrificed for pathological examination. Triphenyl tetrazolium chloride (TTC) assessed myocardial infarction. Microscopy was used to identify myocardial cellular changes. Results: One pig died, 1 pig suffered from aneurysm and another 1 showed negative findings. The other 7 pigs were found with hypokinetic (n=4) or akinetic (n = 3) myocardial regions related to stenosed LCX, their mean WMSI at rest for the lateral and postero-inferior walls (ischemic regions) of the left ventricle was 2.27 +- 0.32 compared with 1.00 +- 0.00 (x2 = 106.27, P 2 = 20.57, P -1·min-1. However, the mean WMSI at the dose of dobutamine 10 and 20 ?g·kg-1·min-1 was 1.70 +- 0.76, 1.75 +- 0.83, respectively, compared with the mean WSCI at rest (x2=3.25 versus 2.33, P > 0.05). The pathologic examination showed viable myocardium at the ischemic regions. Conclusion: Low dose dobutamine (5 ?g·kg-1·min-1) can recover hypokinetic or akinetic myocardial regions, Dobutamine stress MR can detect myocardial viability

  20. Congenital dacryocystocele: prenatal MRI findings

    International Nuclear Information System (INIS)

    Congenital dacryocystocele can be diagnosed prenatally by imaging. Prenatal MRI is increasingly utilized for fetal diagnosis. To present the radiological and clinical features of seven fetuses with congenital dacryocystocele diagnosed with prenatal MRI. The institutional database of 1,028 consecutive prenatal MR examinations performed during a period of 4 years was reviewed retrospectively. The cases of congenital dacryocystocele were identified by reading the report of each MRI study. The incidence of dacryocystocele diagnosed with prenatal MRI was 0.7% (n=7/1,028). The dacryocystocele was bilateral in three fetuses. Mean gestational age at the time of diagnosis was 31 weeks. The indication for prenatal MRI was the presence or the suspicion of central nervous system abnormality in six fetuses and diaphragmatic hernia in one. Dacryocystocele was associated with an intranasal cyst in six of ten eyes. Prenatal sonography revealed dacryocystocele in only two of seven fetuses. Of eight eyes with postnatal follow-up, four did not have any lacrimal symptoms. Prenatal MRI can delineate congenital dacryocystocele more clearly and in a more detailed fashion than ultrasonography. Presence of dacryocystocele was symptomatic in only 50% of our patients, supporting that prenatal diagnosis of dacryocystocele might follow a benign course. (orig.)

  1. Congenital dacryocystocele: prenatal MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Yazici, Zeynep [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Uludag University, Department of Radiology, Faculty of Medicine, Bursa (Turkey); Kline-Fath, Beth M.; Rubio, Eva I.; Calvo-Garcia, Maria A.; Linam, Leann E. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Yazici, Bulent [Uludag University, Department of Ophthalmology, Faculty of Medicine, Bursa (Turkey)

    2010-12-15

    Congenital dacryocystocele can be diagnosed prenatally by imaging. Prenatal MRI is increasingly utilized for fetal diagnosis. To present the radiological and clinical features of seven fetuses with congenital dacryocystocele diagnosed with prenatal MRI. The institutional database of 1,028 consecutive prenatal MR examinations performed during a period of 4 years was reviewed retrospectively. The cases of congenital dacryocystocele were identified by reading the report of each MRI study. The incidence of dacryocystocele diagnosed with prenatal MRI was 0.7% (n=7/1,028). The dacryocystocele was bilateral in three fetuses. Mean gestational age at the time of diagnosis was 31 weeks. The indication for prenatal MRI was the presence or the suspicion of central nervous system abnormality in six fetuses and diaphragmatic hernia in one. Dacryocystocele was associated with an intranasal cyst in six of ten eyes. Prenatal sonography revealed dacryocystocele in only two of seven fetuses. Of eight eyes with postnatal follow-up, four did not have any lacrimal symptoms. Prenatal MRI can delineate congenital dacryocystocele more clearly and in a more detailed fashion than ultrasonography. Presence of dacryocystocele was symptomatic in only 50% of our patients, supporting that prenatal diagnosis of dacryocystocele might follow a benign course. (orig.)

  2. Observation of the CSF pulsatile flow in the aqueduct using cine MRI with presaturation bolus tracking, 3

    International Nuclear Information System (INIS)

    The to-and-fro motion patterns of the CSF flow in the aqueduct in ten normal adults, ten patients with secondary normal-pressure hydrocephalus (NPH), and fourteen patients with idiopathic ventriculomegaly were analyzed using cine MRI with presaturation bolus tracking. The to-and-fro motion patterns of the CSF flow in the aqueduct were thus classified into four types according to their maximum velocity and the relative time duration of their flow in the rostral and caudal directions. The correlation between the clinical symptoms, the CT findings, the RI-cisternography findings, the results of the ICP monitorings, and the CSF pulsatile-flow patterns were then analyzed. In secondary NPH disclosing frequent B waves on ICP monitoring, the maximum velocity of the CSF flow in the aqueduct was over 15 mm/sec, and the duration of the CSF flow was longer in the caudal direction than in the rostral direction. Furthermore, the faster the maximum velocity of the CSF flow, the larger the ventricular size on CT and the more severe the CSF malabsorption on cisternography. In idiopathic ventriculomegaly, only two cases demonstrated the same CSF flow pattern as was shown in secondary NPH; the other cases demonstrated other CSF flow patterns, which were considered to indicate hydrocephalus ex vacuo or arrested hydrocephalus. The CSF pulsatile-flow pattern was assumed to change according to the degree of the CSF circulatory disorder, its compensatory process, and the plasticity of the brain. The investigation of the CSF pulsatile flow gives important information for the evaluation of various hydrocephalic conditions. (author)

  3. SU-C-17A-05: Quantification of Intra-Fraction Motion of Breast Tumors Using Cine-MRI

    Energy Technology Data Exchange (ETDEWEB)

    Heijst, T van; Philippens, M; Bongard, D van den; Asselen, B van; Lagendijk, J; Kleijnen, J; Hartogh, M den [University Medical Center Utrecht, Utrecht (Netherlands)

    2014-06-01

    Purpose: Magnetic resonance imaging (MRI) enables direct characterization of intra-fraction motion ofbreast tumors, due to high softtissue contrast and geometric accuracy. The purpose is to analyzethis motion in early-stage breast-cancer patients using pre-operative supine cine-MRI. Methods: MRI was performed in 12 female early-stage breast-cancer patients on a 1.5-T Ingenia (Philips)wide-bore scanner in supine radiotherapy (RT) position, prior to breast-conserving surgery. Twotwodimensional (2D) T2-weighted balanced fast-field echo (cine-MRI) sequences were added tothe RT protocol, oriented through the tumor. They were alternately acquired in the transverse andsagittal planes, every 0.3 s during 1 min. A radiation oncologist delineated gross target volumes(GTVs) on 3D contrast-enhanced MRI. Clinical target volumes (CTV = GTV + 15 mm isotropic)were generated and transferred onto the fifth time-slice of the time-series, to which subsequents lices were registered using a non-rigid Bspline algorithm; delineations were transformed accordingly. To evaluate intra-fraction CTV motion, deformation fields between the transformed delineations were derived to acquire the distance ensuring 95% surface coverage during scanning(P95%), for all in-plane directions: anteriorposterior (AP), left-right (LR), and caudal-cranial(CC). Information on LR was derived from transverse scans, CC from sagittal scans, AP fromboth sets. Results: Time-series with registration errors - induced by motion artifacts - were excluded by visual inspection. For our analysis, 11 transverse, and 8 sagittal time-series were taken into account. Themedian P95% calculated in AP (19 series), CC (8), and LR (11) was 1.8 mm (range: 0.9–4.8), 1.7mm (0.8–3.6), and 1.0 mm (0.6–3.5), respectively. Conclusion: Intra-fraction motion analysis of breast tumors was achieved using cine-MRI. These first results show that in supine RT position, motion amplitudes are limited. This information can be used for adaptive RT planning, and to develop preoperative partial-breast RT strategies, such asablative RT for early-stage breast-cancer patients.

  4. Usefulness of breath-hold cardiac cine MR imaging with a middle field MRI system

    Energy Technology Data Exchange (ETDEWEB)

    Matsumura, Kentaro; Sato, Kiyoto; Aono, Masaki; Inoshita, Kenji; Utsumi, Naoko [Kagawa Inoshita Hospital, Ohnohara (Japan)

    1999-07-01

    To assess the accuracy of contrast-enhanced, single breath-hold cine MR imaging in calculating left ventricular volume and ejection fraction, we compared MR measurements with those obtained by using cine ventriculography in 60 patients. Fast cine MR images were acquired with a middle field MR system (0.5 T). A breath-hold single slice multi-phase fast gradient-echo (Fast Card) sequence was used to obtain fast cine MR images with the following parameters; TR of 16 ms, TE of 3 ms, flip angle of 30 degree, matrix elements of 256 x 128, view per segment of 6, field of view of 350 x 260 mm and one excitation. Left ventricular end-diastolic volume and ejection fraction obtained with contrast-enhanced Fast Card correlated well with those obtained with cine ventriculography (end-diastolic volume, y=1.00x+14.0, r=0.904, p<0.001; ejection fraction, y=0.961x+2.8, r=0.936, p<0.001). Our results show that contrast enhanced breath-hold cardiac cine MR imaging on horizontal long-axis view using a middle field MR system is an accurate method for evaluating left ventricular volume and ejection fraction. (author)

  5. Neurosarcoidosis with unusual MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Handler, M.S. (Dept. of Pathology and Oncology, Kansas Univ. Medical Center, KS (United States)); Johnson, L.M. (Dept. of Neurology, Kansas Univ. Medical Center, KS (United States)); Dick, A.R. (Dept. of Neurology, Kansas Univ. Medical Center, KS (United States)); Batnitzky, S. (Dept. of Diagnostic Radiology, Kansas Univ. Medical Center, KS (United States))

    1993-02-01

    This 53-year-old white male presented with a 4-month-history of weakness and pain. Despite an initial partial response to steroid therapy, his neurologic deterioration progressed culminating in paraparesis, paresthesias, urinary incontinence, altered mentation and a 20 Ib weight loss. A gadolinium-enhanced MRI study showed a pattern suggestive of perivascular involvement. A subsequent cerebral biopsy was diagnostic for neurosarcoidosis. (orig.)

  6. MRI findings of extramedullary haemopoiesis

    Energy Technology Data Exchange (ETDEWEB)

    Chourmouzi, D.; Pistevou-Gompaki, K.; Plataniotis, G.; Skaragas, G.; Papadopoulos, L.; Drevelegas, A. [Dept. of Diagnostic Radiology and Radiation Oncology, AHEPA University Hospital, Thessaloniki (Greece)

    2001-09-01

    Extramedullary haemopoiesis (EH) is a compensatory process associated with chronic haemolytic anaemia. It is rare, however, for such an abnormality to cause spinal cord compression. We present two patients with known beta-thalassaemia intermedia who developed spinal cord compression due to masses of extramedullary haematopoietic tissue in the epidural space of the thoracic spine. The EH masses were diagnosed by MRI as an isointense epidural lesion on both T1- and T2-weighted images, compressing severely the spinal cord. After administration of a paramagnetic agent, an intermediate enhancement of the masses was evident. All the vertebral bodies had low to intermediate signal intensity as a result of displacement of fatty marrow by haematopoietic marrow. Expansion of thoracic ribs with bilateral paravertebral masses were characteristic. A small dose of radiotherapy was given and marked improvement in neurological symptoms was evident. An MRI examination established shrinkage of the mass and decompression of spinal cord. The role of MRI in diagnosis of EH masses is essential and radiation therapy is a very effective treatment for this rare complication. (orig.)

  7. Respiratory lumenal change of the pharynx and trachea in normal subjects and COPD patients: assessment by cine-MRI

    International Nuclear Information System (INIS)

    The purpose of this study was to use cine-MRI during continuous respiration to measure the respiratory lumenal diameter change in the pharynx and at an upper tracheal level. Fifteen non-smokers and 23 chronic obstructive pulmonary disease (COPD) patients with smoking history (median 50 pack-years) were included. Cine-MRI with seven frames/s was performed during continuous respiration. Minimal and maximal cross-sectional lumenal diameters within the pharynx and the upper tracheal lumen area were measured. The median diameter change in the pharynx (tracheal area) was 70% (1.4 cm2) in volunteers and 76% (1.7 cm2) in smokers (P=0.98, P=0.04). Tracheal lumenal collapse was a median of 43% in volunteers and 64% in smokers (P=0.011). No clear disease-related difference of the pharynx-lumen was found. The maximal cross-sectional area of the upper trachea lumen as well as the respiratory collapse was larger in COPD patients than in normal subjects. This information is important for the modelling of ventilation and prediction of drug deposition, which are influenced by the airway diameter. (orig.)

  8. MRI changes in myocarditis - Evaluation with spin echo, cine MR angiography and contrast enhanced spin echo imaging

    International Nuclear Information System (INIS)

    AIM: Myocarditis is probably under-diagnosed with clinical criteria generally used for diagnosis. Magnetic resonance imaging (MRI) has shown promise in detecting heart muscle disorders and we set out to assess the role of cine magnetic resonance angiography (MRA) and contrast enhancement in myocarditis, as there is a need for a non-invasive tool that can aid prognosis and follow-up. MATERIALS AND METHODS: Twenty patients were evaluated with T1 SE pre- and post-gadolinium enhancement and cine MRA. Four patients were histologically proven to have myocarditis, eight others were diagnosed as having myocarditis by clinical criteria and eight did not have myocarditis. Images were evaluated in a blinded fashion for regional wall motion abnormality and contrast enhancement pattern. Analysis of contrast enhancement by signal intensity measurement was also performed. RESULTS: Focal myocardial enhancement with associated regional wall motion abnormality correlated with myocarditis in 10 out of 12 patients, two patients with abnormal focal enhancement alone also clinically had myocarditis. None of the non-myocarditis patients showed abnormal focal enhancement. Enhancement analysis suggests that focal corrected myocardial enhancement of > 40% is abnormal. CONCLUSION: In the correct clinical context, focal myocardial enhancement on spin echo MRI strongly supports a diagnosis of myocarditis, especially when associated with regional wall motion abnormality. Roditi, G.H. (2000)

  9. Vertebral involvement in SAPHO syndrome: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Nachtigal, A.; Cardinal, E.; Bureau, N.J. [Dept. of Radiology, Univ. de Montreal, QC (Canada); Sainte-Marie, L.G. [Dept. of Internal Medicine, Univ. de Montreal, QC (Canada); Milette, F. [Department of Pathology, Univ. de Montreal, QC (Canada)

    1999-03-01

    We report on the MRI findings in the vertebrae and surrounding soft tissues in two patients with the SAPHO syndrome (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis). The MRI findings include abnormal bone marrow signal, either focal or diffuse, of the vertebral bodies and posterior elements; hyperintense paravertebral soft tissue swelling and abnormal signal of the intervertebral discs. These changes are consistent with discitis and osteitis. (orig.) With 6 figs., 17 refs.

  10. MRI findings of multiple sclerosis

    International Nuclear Information System (INIS)

    Nine patients of clinically definite multiple sclerosis (MS) were examined by magnetic resonance imaging (MRI) at 1.0 T. The MS plaques were seen in the brain and spinal cord in eight and three patients, respectively. The frequent sites of MS plaques were periventricular white matter, brain stem, and cervical cord. The shape of most brain MS plaques was round or finger-like configuration. The MS plaques showed high signal intensity on T2 weighted images and low or iso signal intensity on T1 weighted images in all nine cases. Contrast enhancement was seen in 4 cases. Mild brain atrophy was noted in 2 cases and mass effect in 1 case. The sites of cord MS plaques in three patients were C2-C4, C2-C5, and C4-C6 levels respectively. The core MS plaques showed high signal intensity on T2 weighted image and contrast enhancement on Gd-DTPA enhanced T1 weighted images in all 3 case with mild cord expansion in 2 cases. In conclusion, MRI is a useful diagnosis tool in evaluating the MS plaques involved central nervous system

  11. Is High Temporal Resolution Achievable for Paediatric Cardiac Acquisitions during Several Heart Beats? Illustration with Cardiac Phase Contrast Cine-MRI

    Science.gov (United States)

    Bonnemains, Laurent; Odille, Freddy; Meyer, Christophe; Hossu, Gabriella; Felblinger, Jacques; Vuissoz, Pierre-André

    2015-01-01

    Background During paediatric cardiac Cine-MRI, data acquired during cycles of different lengths must be combined. Most of the time, Feinstein’s model is used to project multiple cardiac cycles of variable lengths into a mean cycle. Objective To assess the effect of Feinstein projection on temporal resolution of Cine-MRI. Methods 1/The temporal errors during Feinstein’s projection were computed in 306 cardiac cycles fully characterized by tissue Doppler imaging with 6-phase analysis (from a population of 7 children and young adults). 2/The effects of these temporal errors on tissue velocities were assessed by simulating typical tissue phase mapping acquisitions and reconstructions. 3/Myocardial velocities curves, extracted from high-resolution phase-contrast cine images, were compared for the 6 volunteers with lowest and highest heart rate variability, within a population of 36 young adults. Results 1/The mean of temporal misalignments was 30 ms over the cardiac cycle but reached 60 ms during early diastole. 2/During phase contrast MRI simulation, early diastole velocity peaks were diminished by 6.1 cm/s leading to virtual disappearance of isovolumic relaxation peaks. 3/The smoothing and erasing of isovolumic relaxation peaks was confirmed on tissue phase mapping velocity curves, between subjects with low and high heart rate variability (p = 0.05). Conclusions Feinstein cardiac model creates temporal misalignments that impair high temporal resolution phase contrast cine imaging when beat-to-beat heart rate is changing. PMID:26599755

  12. MRI findings in the painful hemiplegic shoulder

    International Nuclear Information System (INIS)

    Aim: To evaluate the magnetic resonance imaging (MRI) findings in painful hemiplegic shoulder (PHS) in hemiplegic post-stroke patients. Materials and methods: Patients with hemiplegia following their first cerebrovascular accident who were admitted to the Sarah Network of Hospitals for Rehabilitation were studied. Forty-five patients with pain in the hemiplegic shoulder and 23 post-stroke patients without shoulder pain were investigated. MRI and radiographic findings of the hemiplegic and contralateral asymptomatic shoulders were evaluated. Results: Some MRI findings were more frequent in PHS group, including synovial capsule thickening, synovial capsule enhancement, and enhancement in the rotator cuff interval. Conclusions: Adhesive capsulitis was found to be a possible cause of PHS.

  13. MRI findings in the painful hemiplegic shoulder

    Energy Technology Data Exchange (ETDEWEB)

    Tavora, D.G.F., E-mail: danielgurgel@sarah.b [Department of Radiology, Sarah Network of Hospitals for Rehabilitation, Fortaleza (Brazil); Gama, R.L.; Bomfim, R.C. [Department of Radiology, Sarah Network of Hospitals for Rehabilitation, Fortaleza (Brazil); Nakayama, M. [Department of Radiology, Federal University of Grande Dourados, Dourados (Brazil); Silva, C.E.P. [Department of Statistics, Sarah Network of Hospitals for Rehabilitation, Fortaleza (Brazil)

    2010-10-15

    Aim: To evaluate the magnetic resonance imaging (MRI) findings in painful hemiplegic shoulder (PHS) in hemiplegic post-stroke patients. Materials and methods: Patients with hemiplegia following their first cerebrovascular accident who were admitted to the Sarah Network of Hospitals for Rehabilitation were studied. Forty-five patients with pain in the hemiplegic shoulder and 23 post-stroke patients without shoulder pain were investigated. MRI and radiographic findings of the hemiplegic and contralateral asymptomatic shoulders were evaluated. Results: Some MRI findings were more frequent in PHS group, including synovial capsule thickening, synovial capsule enhancement, and enhancement in the rotator cuff interval. Conclusions: Adhesive capsulitis was found to be a possible cause of PHS.

  14. Fucosidosis: MRI and MRS findings

    Energy Technology Data Exchange (ETDEWEB)

    Oner, Ali Y.; Akpek, Sergin [Gazi University School of Medicine, Department of Radiology, Ankara (Turkey); Cansu, Ali; Serdaroglu, Ayse [Gazi University School of Medicine, Department of Paediatrics, Ankara (Turkey)

    2007-10-15

    Fucosidosis is a rare, autosomal recessive lysosomal storage disease in which fucose-containing glycolipids, glycoproteins, and oligosaccharides accumulate in tissues as a consequence of {alpha}-l-fucosidase enzyme deficiency. We present the MR imaging findings of diffuse white-matter hyperintensity and pallidal curvilinear streak hyperintensity in a 6-year-old Caucasian girl with a diagnosis of fucosidosis based on cDNA isolated from skin fibroblasts. This report also includes the MRS findings of a decreased N-acetylaspartate/choline ratio together with an abnormal peak at 3.8 ppm which expand the knowledge of the neuroradiological spectrum of this rare disease. (orig.)

  15. Fucosidosis: MRI and MRS findings

    International Nuclear Information System (INIS)

    Fucosidosis is a rare, autosomal recessive lysosomal storage disease in which fucose-containing glycolipids, glycoproteins, and oligosaccharides accumulate in tissues as a consequence of ?-l-fucosidase enzyme deficiency. We present the MR imaging findings of diffuse white-matter hyperintensity and pallidal curvilinear streak hyperintensity in a 6-year-old Caucasian girl with a diagnosis of fucosidosis based on cDNA isolated from skin fibroblasts. This report also includes the MRS findings of a decreased N-acetylaspartate/choline ratio together with an abnormal peak at 3.8 ppm which expand the knowledge of the neuroradiological spectrum of this rare disease. (orig.)

  16. Study on MRI findings in postresuscitation brains

    International Nuclear Information System (INIS)

    We evaluated chronological changes in T1/T2-weighted and diffusion-weighted magnetic resonance imaging (MRI) findings in patients with global cerebral ischemia compared to computed tomography (CT) and single photon emission computed tomography (SPECT) to determine the advantages this presents in determining a patient's prognosis. We retrospectively studied MRI in 28 patients resuscitated after cardiopulmonary arrest. Patients were divided by outcome into 4 groups -- good outcome in 5, moderate disability in 2, vegetative in 17, and 4 brain-dead. Those with good recovery had normal CT and MRI findings. Those with moderate disability demonstrated high signal intensity in basal ganglia and posterior cerebral cortex during the chronic period. All vegetative patients had abnormal CT findings and their T2-weighted images during the acute period demonstrated high signal intensity in the cerebral cortex and basal ganglia; T1-weighted image during the chronic period showed similar findings, while diffusion-weighted images indicated high signal intensity in the cerebral cortex from the very acute period, during which abnormal findings were seen in the cortex, putamen, and thalamus more frequently than in T2-weighted images. Moreover, regional cerebral blood flow significantly decreased during the chronic period. All brain-dead patients had CT findings of diffuse cerebral edema and loss of density difference between gray and white matter. T2-weighted images respectively showed an extraordinary high density difference between gray and white matter and diffusion-weighted images high signal density in the whole brain. MRI detects chronologic changes in postresuscitation brain damage better than CT findings. Diffusion-weighted images identify hypoxic-ischemic lesions during the very acute period. MRI thus appears useful in evaluating patient prognosis and care. (author)

  17. Quantification of left ventricular volumes from cardiac cine MRI using active contour model combined with gradient vector flow

    International Nuclear Information System (INIS)

    We investigated the feasibility of combining the active contour model with gradient vector flow (Snakes-GVF) to estimate left ventricular (LV) volumes from cardiac cine magnetic resonance imaging (MRI). MRI data were acquired from 27 patients, including 14 adults (9 men, 5 women, 55.0±23.3 years) and 13 children (10 boys, 3 girls, 2.7±2.1 years) using Gyroscan Intera (1.5 Tesla, Philips Medical Systems). LV volumes were calculated by adding the areas surrounded by the contour extracted by Snakes-GVF and compared with volumes estimated by manual tracing. Those estimated by Snakes-GVF [y (mL)] correlated well with those estimated by manual tracing [x (mL)]. In adult cases, the regression equation and correlation coefficient were y=1.008x-0.517 and 0.996, respectively. In pediatric cases, they were y=1.174x-2.542 and 0.992, respectively. In conclusion, Snakes-GVF is a powerful and useful tool for quantifying LV volumes using cardiac MRI. (author)

  18. Delayed-enhancement MRI of apical hypertrophic cardiomyopathy: assessment of the intramural distribution and comparison with clinical symptoms, ventricular arrhythmias, and cine MRI

    International Nuclear Information System (INIS)

    Background: Hypertrophic cardiomyopathy (HCM) is reported to show patchy midwall myocardial hyper enhancement on delayed-enhancement magnetic resonance imaging (DE-MRI). The intramural distribution of myocardial hyper enhancement and its correlation with clinical symptoms, ventricular arrhythmias, and cardiac function have not been described for symptomatic apical HCM. Purpose: To evaluate the features and significance of myocardial hyper enhancement on DE-MRI in symptomatic apical HCM. Material and Methods: Thirteen patients with symptomatic apical HCM and their 65 apical segments were investigated. Myocardial hyper enhancement and regional and global functional parameters were determined with MRI. We investigated the intramural distribution and frequencies of this myocardial hyper enhancement and compared them with the patients' clinical symptoms, the presence of ventricular arrhythmias, and cine MRI. Results: Eight (61.5%) patients with symptomatic apical HCM displayed apical myocardial hyper enhancement, and 22 (33.8%) of the 65 apical segments examined showed myocardial hyper enhancement. Of the myocardial hyper enhancement observed, 81.8% showed a subendocardial pattern.The Hyperenhanced apical myocardium had a lower percentage of systolic myocardial thickening, and was associated with serious symptoms (e.g. syncope) and ventricular arrhythmias. Conclusion: Patients with symptomatic apical HCM showed myocardial hyper enhancement involving the subendocardial layer, which might be related to regional systolic dysfunction, serious clinical symptoms, and ventricular arrhythmias

  19. Delayed-enhancement MRI of apical hypertrophic cardiomyopathy: assessment of the intramural distribution and comparison with clinical symptoms, ventricular arrhythmias, and cine MRI

    Energy Technology Data Exchange (ETDEWEB)

    Amano, Yasuo; Fukushima, Yoshimitsu; Kumita, Shinichiro (Dept. of Radiology, Nippon Medical School, Tokyo (Japan)), email: yas-amano@nifty.com; Takayama, Morimasa (Dept. of Cardiology, Sakakibara Heart Inst., Tokyo (Japan)); Kitamura, Mitsunobu (Coronary Care Unit, Chiba-Hokuso Hospital of Nippon Medical School, Chiba (Japan))

    2011-07-15

    Background: Hypertrophic cardiomyopathy (HCM) is reported to show patchy midwall myocardial hyper enhancement on delayed-enhancement magnetic resonance imaging (DE-MRI). The intramural distribution of myocardial hyper enhancement and its correlation with clinical symptoms, ventricular arrhythmias, and cardiac function have not been described for symptomatic apical HCM. Purpose: To evaluate the features and significance of myocardial hyper enhancement on DE-MRI in symptomatic apical HCM. Material and Methods: Thirteen patients with symptomatic apical HCM and their 65 apical segments were investigated. Myocardial hyper enhancement and regional and global functional parameters were determined with MRI. We investigated the intramural distribution and frequencies of this myocardial hyper enhancement and compared them with the patients' clinical symptoms, the presence of ventricular arrhythmias, and cine MRI. Results: Eight (61.5%) patients with symptomatic apical HCM displayed apical myocardial hyper enhancement, and 22 (33.8%) of the 65 apical segments examined showed myocardial hyper enhancement. Of the myocardial hyper enhancement observed, 81.8% showed a subendocardial pattern.The Hyperenhanced apical myocardium had a lower percentage of systolic myocardial thickening, and was associated with serious symptoms (e.g. syncope) and ventricular arrhythmias. Conclusion: Patients with symptomatic apical HCM showed myocardial hyper enhancement involving the subendocardial layer, which might be related to regional systolic dysfunction, serious clinical symptoms, and ventricular arrhythmias

  20. Estimation of tissue contractility from cardiac cine-MRI using a biomechanical heart model

    OpenAIRE

    Chabiniok, Radomir; Moireau, Philippe; Lesault, Pierre-François; Rahmouni, Alain; Deux, Jean-Francois; Chapelle, Dominique

    2012-01-01

    The objective of this paper is to propose and assess an estimation procedure - based on data assimilation principles - well-suited to obtain some regional values of key biophysical parameters in a beating heart model, using actual Cine-MR images. The motivation is twofold: (1) to provide an automatic tool for personalizing the characteristics of a cardiac model in order to achieve predictivity in patient-specific modeling, and (2) to obtain some useful information for diagnosis purposes in th...

  1. Lead arthropathy: radiographic, CT and MRI findings

    International Nuclear Information System (INIS)

    Lead arthropathy is a well-known complication of gunshot injuries with retained intra-articular bullets. Although several previous reports have discussed the radiological findings of this entity, computed tomography (CT) and magnetic resonance imaging (MRI) findings have never been described before in this setting. In this paper the authors review the imaging findings of 11 patients with lead arthropathy (1 of whom had clinical signs of lead poisoning as well), all of them studied by means of radiographs. In addition, non-enhanced CT scans were obtained in 3 patients and gadolinium-enhanced MRI in 1. Classic findings of intra-articular speckled lead deposits (occasionally with a ''lead arthrogram'' appearance), joint space narrowing and preserved bone density were found at radiographs in the great majority of cases. Furthermore, extension of intra-articular lead to adjacent tendon sheaths was observed in almost half of the patients, an observation rarely reported in the literature. CT scans and MRI, in their turn, were superior with regard to soft tissue abnormalities, accurately depicting joint effusion and the thickened synovium with lead particles embedded in it. Post-gadolinium MRI had the advantage of showing the enhancement pattern of the inflamed synovium and associated bone marrow edema pattern. Although it is not possible to establish the role of axial imaging in lead arthropathy from the small number of cases studied, this initial experience shows that both methods hold promise in this setting and may be useful, at least in selected cases. (orig.)

  2. MRI findings of treated bacterial septic arthritis

    Energy Technology Data Exchange (ETDEWEB)

    Bierry, Guillaume; Huang, Ambrose J.; Chang, Connie Y.; Torriani, Martin; Bredella, Miriam A. [Massachusetts General Hospital and Harvard Medical School, Musculoskeletal Imaging and Intervention, Department of Radiology, Boston, MA (United States)

    2012-12-15

    The purpose of this study was to report the MRI findings that can be encountered in successfully treated bacterial septic arthritis. The study included 12 patients (8 male and 4 female; mean age 38 years, range 9-85) with 13 proven cases of bacterial septic arthritis. The joints involved were hip (n = 3), knee (n = 3), shoulder (n = 2), sacroiliac (n = 2), ankle (n = 1), wrist (n = 1), and elbow (n = 1). MRI examinations following surgical debridement and at initiation of antibiotic therapy and after successful treatment were compared for changes in effusion, synovium, bone, and periarticular soft tissues. Imaging findings were correlated with microbiological and clinical findings. Joint effusions were present in all joints at baseline and regressed significantly at follow-up MRI (p = 0.001). Abscesses were present in 5 cases (38 %), and their sizes decreased significantly at follow-up (p = 0.001). Synovial enhancement and thickening were observed in all joints at both baseline and follow-up MRI. Myositis/cellulitis was present in 10 cases (77 %) at baseline and in 8 cases (62 %) at follow-up MRI. Bone marrow edema was present in 10 joints (77 %) at baseline and persisted in 8 joints (62 %). Bone erosions were found in 8 joints (62 %) and persisted at follow-up MRI in all cases. The sizes of joint effusions and abscesses appear to be the factors with the most potential for monitoring therapy for septic arthritis, since both decreased significantly following successful treatment. Synovial thickening and enhancement, periarticular myositis/cellulitis, and bone marrow edema can persist even after resolution of the infection. (orig.)

  3. CT and MRI findings of sarcomatoid cholangiocarcinoma

    OpenAIRE

    Bilgin, Mehmet; Toprak, Huseyin; Sennur Bilgin, S.; Kondakci, Mustafa; BALCI, CEM

    2012-01-01

    Computed tomography (CT) and magnetic resonance imaging (MRI) findings for a case of intrahepatic sarcomatoid cholangiocarcinoma is presented. A 48-year-old man with upper abdominal pain underwent contrast-enhanced CT and MRI. A 13?×?10?×?7?cm mass was seen in the left liver lobe, which had hypodense internal architecture on CT and mixed signal intensities on both T1- and T2-weighted images with an overwhelmingly hypointense signal on T1-weighted images and a hyperintense signal on T2-weighte...

  4. MRI Findings in Patients with TMJ Click

    Directory of Open Access Journals (Sweden)

    Mahrokh Imanimoghaddam

    2013-12-01

    Full Text Available Introduction: It has been shown that joint click, an initial and common finding in internal derangement (ID, respond to neither conservative treatment nor surgical intervention. This raises the question as to whether it must be treated in the absence of other pertinent signs and symptoms, so the aim of this study was to investigate and compare the MRI findings of TMJ in both normal subjects and patients with click, in order to determine the importance of click in predicting TMJ pathological changes. Methods: A total of 26 patients with clinical symptoms of disk displacement with reduction (DDwR according to RDC/TMD were compared to 14 normal subjects in terms of their MRI findings, including disk displacement, effusion, condylar osteoarthritic changes and disk deformities. Results: Out of 80 joints in total (52 affected joints in 26 patients and 28 joints in control group, 48 were shown with normal disk position in MRI whereas 28 (35% and 4 (5% were categorised as DDwR and (disk displacement without reduction DDwoR, respectively. Statistically significant correlations were established between the following pairs of variables in order: Click and disk displacement, effusion and disk displacement, disk displacement and effusion with disk deformity. Conclusion: The correlation between the presence of click and disk displacement, disk deformity and effusion emphasizes the importance of MRI for an accurate diagnosis and development of an appropriate treatment plan in these cases and shows that clinical examination is not sufficient for these purposes.

  5. MRI findings of achilles tendon rupture

    International Nuclear Information System (INIS)

    Objective: To evaluate the MRI findings of achilles tendon rupture. Methods: The MRI data of 7 patients with achilles tendon rupture were retrospectively analysed. All 7 patients were male with the age ranging from 34 to 71 years. Routine MR scanning was performed in axial and sagittal planes, including T1WI, T2WI and a fat suppression MRI (SPIR). Results: Among 7 patients, complete achilles tendon rupture was seen in 6 cases, partial achilles tendon rupture 1 case. The site of tendon disruption were 2.6-11.0 cm( mean 5.4 cm) proximal to the insertion in the calcaneus. The MRI findings of a partial or complete rupture of the achilles tendon included enlarged and thickened achilles tendon (7 cases), wavy lax achilles tendon (2 cases), discontinuity of some or all of its fibers and intratendinous regions of increased signal intensity (7 cases). In the cases of complete tendon rupture, the size of the tendinous gap varied from 3.0-8.0 mm, which was filled with blood and appeared as edema of increase signal intensity on T2WI and SPIR. In all 7 patients, MR scanning showed medium signal intensity (7 cases) on T1WI, or medium signal intensity (1 cases), medium-high signal intensity (3 cases ), high signal intensity (3 cases) on T2WI, and medium-high signal intensity (2 cases), high signal intensity (5 cases) on fat suppression MRI. The preachilles fat pad showed obscure in 6 cases of complete achilles tendon rupture. Conclusion: MRI is an excellent method for revealing achilles tendon rupture and confirming the diagnosis. (authors)

  6. MRI findings of Ramsay Hunt syndrome

    International Nuclear Information System (INIS)

    Objective: To investigate the MR findings and diagnostic value in Ramsay Hunt syndrome. Methods: MRI plain and Gd-DTPA enhanced scans were performed in 5 unilateral Ramsay Hunt syndrome patients proved by clinical representation and examinations. The patients included 3 men and 2 women, and their age ranged from 29 to 54 years. The signal intensities of segments of facial nerves within temporal bone were measured pre- and post-gadolinium injections in 3 cases. Of all 5 cases, bilateral contrast of segments of facial nerves at both pre- and post-gadolinium injections was made. Results: Segmental enhancement was found in 4 cases (the difference of bilateral enhancement signal intensities>20, or the grade of difference is 1 or above), while no difference of bilateral enhancement was found in 1 case. Abnormal enhancement of ganglion geniculi (4/4) and labyrinthine segment (3/4) was relatively frequent, abnormal enhancement of distal part of internal auditory segment, tympanic segment, and mastoid segment was seen in 2 cases, respectively. Conclusion: MRI doesn't have diagnostic value unless the enhancement of segments of the affected facial nerve side is more evident than the unaffected side for unilateral cases. Labyrinthine segment and ganglion geniculi are more susceptible to Ramsay Hunt syndrome. Gd-DTPA enhanced MRI can demonstrate segmental lesions of facial nerves objectively, thus it can be helpful in the diagnosis and differential diagnosis of Ramsay Hunt syndrome. The relationship between MRI findings and clinical representation still needs further study

  7. Brain MRI findings of neuropsychiatric lupus

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jang-Wook; Kwon, Bae Ju; Lee, Seung-Ro; Hahm, Chang-Kok; Moon, Won Jin; Jeon, Eui Yong; Bae, Sang-Chul [Hanyang Univ. School of Medicine, Seoul (Korea, Republic of)

    2000-12-01

    To evaluate the brain MRI findings in patients with neuropsychiatric lupus. In 26 patients (M:F = 2:24 ; aged 9-48 years) in whom the presence of systemic lupus erythematosus was clinically or pathologically proven and in whom neuropsychiatric lupus was also clinically diagnosed, the findings of brain MRI were retrospectively evaluated. MR images were analyzed with regard to the distribution, location, size and number of lesions due to cerebral ischemia or infarction, the presence of cerebral atrophy, and the extent and degree of brain parenchymal and intravascular enhancement. The most common MRI findings were lesions due to cerebral ischemia or infarction occurring in 18 patients (69%), and located within deep periventricular white matter (n=10), subcortical white matter (n=8), the cerebral cortex (n=7), basal ganglia (n=7), or brain stem or cerebellum (n=2). The lesions were single (n=3) or multiple (n=15), and in 17 patients were less than 1cm in diameter in regions other than the cerebral cortex. In six of these patients, lesions of 1-4cm in diameter in this region were combined, and one occurred in the cerebral cortex only. Cerebral atrophy was seen in 16 patients (62%), in ten of whom there was no past history of treatment with steroids for more than six months. In 15 patients (58%), contrast-enhanced MR image revealed diffuse enhancement of the basal ganglia or intravascular enhancement. In no case were MRI findings normal. The primary mainfestations of neuropsychiatric lupus are multifocal ischemia or infarctions in the cerebral cortex, and subcortical and deep white matter, and the cerebral atrophy. Contrast-enhanced MR images also demonstrated diffuse enhancement of the basal ganglia and intravascular enhancement, both thought to be related to the congestion due to the stagnation of cerebral blood flow.

  8. Brain MRI findings of neuropsychiatric lupus

    International Nuclear Information System (INIS)

    To evaluate the brain MRI findings in patients with neuropsychiatric lupus. In 26 patients (M:F = 2:24 ; aged 9-48 years) in whom the presence of systemic lupus erythematosus was clinically or pathologically proven and in whom neuropsychiatric lupus was also clinically diagnosed, the findings of brain MRI were retrospectively evaluated. MR images were analyzed with regard to the distribution, location, size and number of lesions due to cerebral ischemia or infarction, the presence of cerebral atrophy, and the extent and degree of brain parenchymal and intravascular enhancement. The most common MRI findings were lesions due to cerebral ischemia or infarction occurring in 18 patients (69%), and located within deep periventricular white matter (n=10), subcortical white matter (n=8), the cerebral cortex (n=7), basal ganglia (n=7), or brain stem or cerebellum (n=2). The lesions were single (n=3) or multiple (n=15), and in 17 patients were less than 1cm in diameter in regions other than the cerebral cortex. In six of these patients, lesions of 1-4cm in diameter in this region were combined, and one occurred in the cerebral cortex only. Cerebral atrophy was seen in 16 patients (62%), in ten of whom there was no past history of treatment with steroids for more than six months. In 15 patients (58%), contrast-enhanced MR image revealed diffuse enhancement of the basal ganglia or intravascular enhancement. In no case were MRI findings normal. The primary mainfestations of neuropsychiatric lupus are multifocal ischemia or infarctions in the cerebral cortex, and subcortical and deep white matter, and the cerebral atrophy. Contrast-enhanced MR images also demonstrated diffuse enhancement of the basal ganglia and intravascular enhancement, both thought to be related to the congestion due to the stagnation of cerebral blood flow

  9. Postoperative MRI findings after cholesteatoma surgery

    International Nuclear Information System (INIS)

    This study was designed to show MRI findings of postoperative middle ear pathologies and to discuss the usefulness of Gadolinium-enhanced MRI in evaluating the postoperative state of cholesteatoma. Thirty-eight ears which underwent intact canal wall tympanoplasty for cholesteatoma were examined. Recurrent cholesteatoma was detected as an iso-intensity area on T1-weighted images with negative enhancement. Notably, residual cholesteatoma were generally depicted as a round iso-intensity area with negative enhancement. Residual cholesteatoma less than 5 mm in diameter were, however, not generally detectable with our MRI scanner. Granulation tissue can be separated from cholesteatoma as an area with positive enhancement. Cholesterol granuloma shows a characteristic high signal pattern on both T1 and T2-weighted images. Hypovascular fibrous tissue and fluid collection may be depicted as a pattern similar to that of cholesteatoma. However, the signal is usually more homogeneous than that of cholesteatoma. We conclude that Gadolinium-enhanced MRI is useful for detecting postoperative cholesteatoma and avoiding unnecessary second-look operations after cholesteatoma surgery, by the canal-up procedure. (author)

  10. Extra-mammary findings in breast MRI

    Energy Technology Data Exchange (ETDEWEB)

    Rinaldi, Pierluigi; Costantini, M.; Belli, P.; Giuliani, M.; Bufi, E.; Fubelli, R.; Distefano, D.; Romani, M.; Bonomo, L. [Catholic University - Policlinic A. Gemelli, Department of Bio-Imaging and Radiological Sciences, Rome (Italy)

    2011-11-15

    Incidental extra-mammary findings in breast Magnetic Resonance Imaging (MRI) may be benign in nature, but may also represent a metastasis or another important lesion. We aimed to analyse the prevalence and clinical relevance of these unexpected findings. A retrospective review of 1535 breast MRIs was conducted. Only axial sequences were reassessed. Confirmation examinations were obtained in all cases. 285 patients had a confirmed incidental finding, which were located in the liver (51.9%), lung (11.2%), bone (7%), mediastinal lymph nodes (4.2%) or consisted of pleural/pericardial effusion (15.4%). 20.4% of incidental findings were confirmed to be malignant. Positive predictive value for MRI to detect a metastatic lesion was high if located within the bone (89%), lymph nodes (83%) and lung (59%), while it was low if located within the liver (9%) or if it consisted of pleural/pericardial effusion (6%). The axial enhanced sequence showed superior sensitivity to unenhanced images in detecting metastatic lesions, especially if only smaller ({<=}10 mm.) lesions were considered. The prevalence of metastatic incidental extra-mammary findings is not negligible. Particular attention should be to incidental findings located within the lung, bone and mediastinal lymph nodes. (orig.)

  11. Clinical usefulness of cine MRI for evaluation of left ventricular volume and diagnosis of heart and great vessel diseases

    Energy Technology Data Exchange (ETDEWEB)

    Kondo, Takeshi; Anno, Hirofumi; Uritani, Tomizo (Fujita-Gakuen Health Univ., Toyoake, Aichi (Japan)) (and others)

    1990-01-01

    ECG-gated cine mode magnetic resonance (MR) imaging was performed in 20 patients with various heart deseases. Left ventricular volume (LVV) and left ventricular ejection fraction (LVEF) were calculated on MR images obtained in left ventricular vertical and horizontal long axis views. The findings were compared with those obtained from left ventriculography. There was a significant positive correlation between MR imaging and ventriculography for both LVV and LVEF (p<0.001). In Marfan syndrome after surgery for dissecting aneurysm of the aorta, MR imaging was capable of visualizing not only the whole aorta in a single plane but also enlargement of the aortic root. It also depicted asynergy and thinned wall of the infarcted myocardium for myocardial infarction; an enlarged left auricle, the thickened septum, and constricted outflow tract for idiopathic hypertrophic subaortic stenosis; shunt flow for ventricular septum defect; and an enlarged aortic root for aortitis syndrome. Using ventriculography as the standard, cine MR imaging was frequently false positive for the detection of mitral regurgitation. There was, however, good concordance between MR imaging and ventriculography in detecting aortic regurgitation. In addition, MR imaging was equivalent to color Doppler technique for detecting valvular regurgitation. (N.K.).

  12. Assessment of left ventricular function with single breath-hold highly accelerated cine MRI combined with guide-point modeling

    Energy Technology Data Exchange (ETDEWEB)

    Heilmaier, Christina, E-mail: christina.heilmaier@uni-due.d [Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen (Germany); Nassenstein, Kai, E-mail: kai.nassenstein@uni-due.d [Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen (Germany); Nielles-Vallespin, Sonia, E-mail: sonia.nielles-vallespin@siemens.co [Siemens AG Healthcare Sector, MED MR PLM AW Cardiology, Erlangen (Germany); Zuehlsdorff, Sven, E-mail: sven.zuehlsdorff@siemens.co [Siemens AG Healthcare Sector, Cardiovascular MR Research and Development, Chicago (United States); Hunold, Peter, E-mail: peter.hunold@uni-due.d [Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen (Germany); Barkhausen, Joerg, E-mail: joerg.barkhausen@uk-sh.d [Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen (Germany)

    2010-06-15

    Purpose: To prospectively assess the performance of highly accelerated cine MRI in multi-orientations combined with a new guide-point modeling post-processing technique (GPM approach) for assessment of left ventricular (LV) function compared to the standard summation of slices method based on a stack of short axis views (SoS approach). Materials and methods: 33 consecutive patients were examined on a 1.5 T scanner with a standard steady state free precession (SSFP) sequence (TR, 3.0 ms; TE, 1.5 m; flip angle (FA), 60{sup o}; acceleration factor (AF), 2) analyzed with the SoS method and a highly accelerated, single breath-hold temporal parallel acquisition SSFP sequence (TR, 4.6 ms; TE, 1.1 ms; AF, 3) post-processed with the GPM method. LV function values were measured by two independent readers with different experience in cardiac MRI and compared by using the paired t-test and F-test. Inter- and intraobserver agreements were calculated using Bland-Altman-Plots. Results: Mean acquisition and post-processing time was significantly shorter with the GPM approach (15 s/3 min versus 360 s/6 min). For all LV function parameters interobserver agreement between the experienced and non-experienced reader was significantly improved when the GPM approach was used. However, end-diastolic and end-systolic volumes were larger for the GPM technique when compared to the SoS method (P < 0.001), whereas ejection fraction estimation yielded equivalent results (P > 0.121). In both readers and for all parameters variances did not differ significantly (P {>=} 0.409) and the two approaches showed an excellent linear correlation (r > 0.951). Conclusion: Due to its accurate, fast and reproducible assessment of LV function parameters highly accelerated MRI combined with the GPM technique may become the technique of first choice for assessment of LV function in clinical routine.

  13. Periarthritis of the shoulder-MRI findings

    International Nuclear Information System (INIS)

    We examined MRI findings in patients with periarthritis of the shoulder. We excluded cuff tears, calcified tendinitis, instability of the shoulder, fracture and impingement syndrome of young patients. Subjects comprised 36 cases, 38 shoulders (25 men and 11 women), with an average age of 59.1 years (42-75). Scanning was performed on a Gyroscan T5-II 0.5-T (Philips). T1-weighted and T2-weighted sequences in the coronal oblique plane, T2-weighted sequences in the coronal sagittal plane and horizontal plane were taken. Twelve shoulders showed some change in the humeral heads. Degeneration of the rotator cuff was observed in 15 shoulders. Joint fluid collection was observed in the gleno-humeral joints of 15 shoulders, in the subacromial bursa of 11 shoulders and in the acromio-clavicular joints of 7 shoulders. Twenty four shoulders had fluid collection in the sheath of the long head of the biceps long tendon. Localized high signal area was observed around the inferior pouch in 11 shoulders. We studied the relationship between MRI findings and clinical symptoms. There was no significant relationship but the shoulders with night pain and severe contractures had a higher positive rate of joint fluid collection on MRI than the shoulders without night pain and with less contractures. (author)

  14. MRI findings of dysplasia epiphysealis hemimelica

    International Nuclear Information System (INIS)

    We report a boy with dysplasia epiphysealis hemimelica of the knee, particularly emphasizing MRI findings. When he was 14 months of age, plain radiography exhibiting juxta-articular soft tissue mass with small, punctate, calcified foci did not warrant the definitive diagnosis, while MRI clearly demonstrated osteocartilaginous overgrowth of the femoral epiphysis. The epiphyseal mass mostly showed the same signal intensity as normal cartilage but contained low signal spots corresponding to calcified foci. The cartilaginous cap was depicted as a mottled area of high intensity on a T2-weighted image. When the patient was 4 years of age, this ossified mass was resected surgically and pathologically identified as osteochondroma incorporated into the epiphysis. (orig.)

  15. MRI findings of dysplasia epiphysealis hemimelica

    Energy Technology Data Exchange (ETDEWEB)

    Iwasawa, T. [Dept. of Radiology, School of Medicine, Yokohama City Univ., Kanagawa (Japan); Aida, N. [Dept. of Radiology, School of Medicine, Yokohama City Univ., Kanagawa (Japan)]|[Kanagawa Children`s Medical Center, Yokohama (Japan); Kobayashi, N. [Dept. of Radiology, School of Medicine, Yokohama City Univ., Kanagawa (Japan)]|[Kanagawa Children`s Medical Center, Yokohama (Japan); Nishimura, G. [Dept. of Radiology, School of Medicine, Yokohama City Univ., Kanagawa (Japan)]|[Dept. of Radiology, School of Medicine, Dokkyou Univ., Tochigi (Japan)

    1996-01-01

    We report a boy with dysplasia epiphysealis hemimelica of the knee, particularly emphasizing MRI findings. When he was 14 months of age, plain radiography exhibiting juxta-articular soft tissue mass with small, punctate, calcified foci did not warrant the definitive diagnosis, while MRI clearly demonstrated osteocartilaginous overgrowth of the femoral epiphysis. The epiphyseal mass mostly showed the same signal intensity as normal cartilage but contained low signal spots corresponding to calcified foci. The cartilaginous cap was depicted as a mottled area of high intensity on a T2-weighted image. When the patient was 4 years of age, this ossified mass was resected surgically and pathologically identified as osteochondroma incorporated into the epiphysis. (orig.)

  16. Symptomatic Chiari malformation in infancy and adolescence; Cine-MRI and clinical evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Fukushima, Takeo; Matsuda, Toshihiro; Tsugu, Hitoshi; Sakamoto, Seisaburou; Tomonaga, Masamichi; Asakawa, Koji; Mitsudome, Akihisa (Fukuoka Univ. (Japan). School of Medicine); Hashimoto, Takahisa

    1994-04-01

    Of the 7 children and adolescents with Chiari malformation reported here 5 had Chiari type 1 and 2 had Chiari type 2 disease. All 5 Chiari type 1 patients had syringomyelia and scoliosis, but the Chiari type 2 patients did not. All the patients except one with localized syringomyelia (case 3) underwent posterior decompression with suboccipital craniectomy, upper cervical laminectomy and duraplasty, and their clinical signs and symptoms improved. Case 3 received a syringo-subarachnoid shunt and improved clinically. Motor function was restored better than sensory function. Cranial nerve signs were cleared up in the Chiari type 2 patients. In the Chiari type 1 patients postoperative neurological improvement correlated well with the collapse of syringomyelia. Cine MR imaging was useful in the evaluation of CSF dynamics at the cranio-vertebral junction and in the syringomyelic cavity before and after surgery. (author).

  17. Brain MRI findings following cardiac arrest

    International Nuclear Information System (INIS)

    Brain damage, involving the grey matter in particular, is a result of hypoxic/ischemic changes after cardiac arrest. To present the spectrum of brain MRI findings in cardiac arrest survivors. MRI (9) and CT (1) were performed in 10 patients, aged 9 - 69 years, 2 days -3 months after cardiac arrest. Standard and diffusion-weighed images were obtained. Brain lesions were found in 7 patients.In 6 of them, grey matter was involved (lentiform and caudate nuclei in 2, nuclei and cortex in 4). In 2 patients, white matter abnormalities were found in addition to grey matter lesions, in 1 case, the white matter was involved only. In 3 patients, including 1 still unconscious, no abnormalities were observed. Our results are consistent with those reported by other authors. MRI is the most sensitive method of detection and characterisation of brain lesions after cardiac arrest. DWI plays the most important role, especially in the acute and subacute period and in cases with normal standard imaging results. (author)

  18. Percent wall thickness evaluated by Gd-DTPA enhanced cine MRI as an indicator of local parietal movement in hypertrophic cardiomyopathy

    International Nuclear Information System (INIS)

    Hypertrophic cardiomyopathy (HCM) is a cardiac disease, the basic pathology of which consists of a decrease in left ventricular dilation compliance due to uneven hypertrophy of the left ventricular wall. Magnetic resonance imaging (MRI) is useful in monitoring uneven parietal hypertrophy and kinetics in HCM patients. The present study was undertaken in 47 HCM patients who showed asymmetrical septal hypertrophy to determine if percent thickness can be an indicator of left ventricular local movement using cine MRI. Longest and shortest axis images were acquired by the ECG synchronization method using a 1.5 T MR imager. Cardiac function was analyzed based on longest axis cine images, and telediastolic and telesystolic parietal thickness were measured based on shorter axis cine images at the papillary muscle level. Parietal movement index and percent thickness were used as indicators of local parietal movement. The correlation between these indicators and parietal thickness was evaluated. The percent thickness changed at an earlier stage of hypertrophy than the parietal movement index, thus it is thought to be useful in detecting left ventricular parietal movement disorders at an early stage of HCM. (author)

  19. Percent wall thickness evaluated by Gd-DTPA enhanced cine MRI as an indicator of local parietal movement in hypertrophic cardiomyopathy

    Energy Technology Data Exchange (ETDEWEB)

    Hirano, Masaharu [Tokyo Medical Coll. (Japan)

    1998-11-01

    Hypertrophic cardiomyopathy (HCM) is a cardiac disease, the basic pathology of which consists of a decrease in left ventricular dilation compliance due to uneven hypertrophy of the left ventricular wall. Magnetic resonance imaging (MRI) is useful in monitoring uneven parietal hypertrophy and kinetics in HCM patients. The present study was undertaken in 47 HCM patients who showed asymmetrical septal hypertrophy to determine if percent thickness can be an indicator of left ventricular local movement using cine MRI. Longest and shortest axis images were acquired by the ECG synchronization method using a 1.5 T MR imager. Cardiac function was analyzed based on longest axis cine images, and telediastolic and telesystolic parietal thickness were measured based on shorter axis cine images at the papillary muscle level. Parietal movement index and percent thickness were used as indicators of local parietal movement. The correlation between these indicators and parietal thickness was evaluated. The percent thickness changed at an earlier stage of hypertrophy than the parietal movement index, thus it is thought to be useful in detecting left ventricular parietal movement disorders at an early stage of HCM. (author)

  20. MRI findings of temporal lobe ganglioglioma

    International Nuclear Information System (INIS)

    Ganglioglioma is a rare primary brain tumor usually found in the temporal lobe. The purpose of this study is to describe the characteristic MR findings of temporal lobe ganglioglioma. Over a seven-year period, ten patients with cerebral ganglioglioma were evaluated at our institution. Seven cases of temporal lobe ganglioma were found ; six of these involved men, and one, a woman ; their mean age was 29.6 years. In three patients, Gd-DTPA-enhanced T1-weighted images were also obtained. We retrospectively analysed the MRI findings with respect to location, size, cortical involvement, margin, cystic change, degree of enhancement, MR signal intensity, calcification and peritumoral change. In five cases, tumors were located within the temporal lobe. In one, a tumor extended from the temporal lobe to the thalamus, and in one from the temporal lobe to the thalamus and cerebral peduncle. All temporal gangliogliomas measured 1.6-3.8cm in their greatest diameter (mean diameter, 2.7cm). In all cases, the cortices were involved with the maintenance of gyriform. The tumor margin was ill defined in five cases and well defined in two. Tumors showed multiple small cystic changes in four cases, a large cyst in two, and a solid nodule in one. In three cases in which contrast media was administered, no lesions were enhanced. On T1-weighted images, iso-signal intensities were seen in five cases and high signal intensities in two. On T2-weighted images, the corresponding figures were five and two. On MRI, tumor calcification and calvarial erosion were each detected in two cases. In patients with temporal lobe epilepsy in whom cortical solid or cystic and poorly enhanced lesions were seen on brain MRI, and in whom associated findings such as calcification and or adjacent bony erosion were noted, ganglioglioma must be considered

  1. Increased pulsatile movement of the hindbrain in syringomyelia associated with the Chiari malformation: cine-MRI with presaturation bolus tracking

    International Nuclear Information System (INIS)

    Cine-MRI with presaturation bolus tracking was used in patients with syringomyelia associated with a Chiari malformation to study pulsatile movement of the hindbrain, cervical spinal cord, cerebrospinal fluid and the fluid within the syrinx. Nine patients had 13 examinations, 6 preoperative, 3 after syringosubarachnoid shunting and 4 after posterior fossa decompression. Five controls were also examined. Dynamic display of the acquired images demonstrated downward displacement of the presaturation bolus on the cerebellar tonsils and medulla oblongata (or upper cervical cord) at the C1 level in all preoperative examinations and in two patients after syringo-subarachnoid shunting but with residual foramen magnum obstruction. Downward displacement of the bolus on the cervical spinal cord was also demonstrated in 7 examinations, but not observed in the controls. Thus, the hindbrain-spinal cord axis showed larger pulsatile movements in patients with foramen magnum obstruction. Based on these observations and a review of the literature, a new theory on the mode of extension of syringomyelia, emphasising the role of increased pulsatile movement of the hindbrain-spinal cord axis is proposed: that the pulsatile movements, together with a one-way valve mechanism in the syrinx cavity act as a ''vacuum-pump'' to enlarge the syrinx. (orig.)

  2. MRI findings of temporal lobe epilepsy

    International Nuclear Information System (INIS)

    MRI findings were analyzed retrospectively in 46 patients with temporal lobe epilepsy in which the side of epileptogenic focus had been confirmed by EEG studies. T1- and T2-weighted images were obtained by the use of a 1.0 or 1.5 T superconducting-type MRI machine with a coronal scan perpendicular to the axis of the temporal horn of the lateral ventricle. Additional axial and sagittal scans were performed in some cases. The area of the hippocampal body was measured quantitatively using a computerized image-analysis system in 26 cases in which the hippocampus had been visualized with enough contrast on T1-weighted coronal images. Abnormal findings were observed in 31/46 (67%) cases. Hippocampal (HC) and temporal lobe (TL) atrophy were observed in 18/46 (39%) and 23/46 (50%) cases respectively, and the side of the atrophy corresponded with the side of the epileptogenic focus, as confirmed by EEG studies, with specificities of 89% and 74% respectively. A quantitative measurement of the area of the hippocampal body showed unilateral hippocampal atrophy more than 10% in 18/25 (69%) cases (10-25%: 10 cases, 25-50%: 7 cases, 50%2 abnormality was observed in only 4 cases. Structural lesions were observed in 4 cases including an arachnoid cyst, an astrocytoma in amygdala, the Dandy-Walker syndrome, and tuberous sclerosis, using the more efficient imaging qualities than the CT scan. From these observations, it is apparant that superconducting MRI is extremely useful in the diagnosis of the epileptogenic topography of temporal lobe epilepsy. Particularly, hippocampal atrophy was found to correspond with the side of the epileptogenic focus on EEG with a high specificity; its quantitative evaluation could be one of the most important standards in detecting the operative indications for temporal lobe epilepsy. (author)

  3. Semi-quantitative evaluation of aortic valve insufficiency by means of cine MRI compared with colour Dopplerecho-cardiography and cardio-angiography

    International Nuclear Information System (INIS)

    A simple, reliable semi-quantitative method for evaluating aortic valve insufficiency by means of cine MR is described. Ten normal persons and 36 patients with aortic valve abnormalities were examined in a 1.5 Tesla apparatus using ECG-triggered gradient echo sequences. The heart was imaged along its short axis. Semi-quantitative evaluation of aortic valve insufficiency was calculated from an MRI index, which depends on the diameter of the aortic regurgitant jet and on its length; the results were compared with colour Doppler echo-cardiography and cardio-angiography. The MRI index showed better correlation with cardio-angiography (r = 0.92) than the correlation between the colour Doppler echo-cardiography and cardio-angiography (r = 0.78). Over and under estimates are less common with MRI than with colour Doppler echo-cardiography. MRI showed very little inter-observer variability (r = 0.96, p <0.001). Cine MR is a reliable method for demonstrating aortic valve insufficiency. Using the short axis of the heart, rapid semi-quantitative evaluation of the aortic regurgitant jet is regularly possible. (orig.)

  4. Early MRI findings of rapidly destructive coxarthrosis

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Wataru; Itoi, Eiji; Yamada, Shin [Department of Orthopedic Surgery, Akita University School of Medicine (Japan)

    2002-01-01

    Rapidly destructive coxarthrosis (RDC) is known to affect elderly women, but its etiology is unknown. This is the first report to our knowledge, based on a search of the English literature, that reveals the entire process of hip destruction from the onset to the terminal stage of RDC, in an 80-year-old woman. Radiographic evaluation showed subchondral insufficiency fracture of the femoral head at an early stage of this disease. An MRI examination within a month of the onset of hip pain showed the entire femoral head with low intensity on T1-weighted images and high intensity on T2-weighted images, and a small low-intensity band at the subchondral area of the lateral weight-bearing portion of the head. These findings are consistent with subchondral insufficiency fracture and associated bone marrow edema. The lesion developed into a deep and large erosion at the superolateral portion of the femoral head, the process being observed on both roentgenograms and MRI. These findings were confirmed during total hip arthroplasty. This case suggests that subchondral insufficiency fracture of the femoral head may be a preceding sign of destruction of the femoral head. (orig.)

  5. Single breath hold 3D cardiac cine MRI using kat-ARC: preliminary results at 1.5T.

    Science.gov (United States)

    Jeong, Daniel; Schiebler, Mark L; Lai, Peng; Wang, Kang; Vigen, Karl K; François, Christopher J

    2015-04-01

    Validation of a new single breath-hold, three-dimensional, cine balanced steady-state free precession (3D cine bSSFP) cardiac magnetic resonance (CMR) sequence for left ventricular function. CMR examinations were performed on fifteen patients and three healthy volunteers on a clinical 1.5T scanner using a two-dimensional (2D) cine balanced SSFP CMR sequence (2D cine bSSFP) followed by an investigational 3D cine bSSFP pulse sequence acquired within a single breath hold. Left ventricular end diastolic volume (LVEDV), end systolic volume (LVESV), ejection fraction (LVEF), and myocardial mass were independently segmented on a workstation by two experienced radiologists. Blood pool to myocardial contrast was evaluated in consensus using a Likert scale. Bland-Altman analysis was used to compare these quantitative and nominal measurements for the two sequences. The average acquisition time was significantly shorter for the 3D cine bSSFP than for 2D cine bSSFP (0.36 ± 0.03 vs. 8.5 ± 2.3 min) p = 0.0002. Bland-Altman analyses [bias and (limits of agreement)] of the data derived from these two methods revealed that the LVEF 0.9% (-4.7, 6.4), LVEDV 4.9 ml (-23.0, 32.8), LVESV -0.2 ml (-22.4, 21.9), and myocardial mass -0.4 g (-23.8, 23.0) were not significantly different. There was excellent intraclass correlation for intra-observer variability (0.981, 0.989, 0.997, 0.985) and inter-observer variability (0.903, 0.954, 0.970, 0.842) for LVEF, LVEDV, LVESV, and myocardial mass respectively. 3D cine bSSFP allows for accurate single breath-hold volumetric cine CMR which enables substantial improvements in scanner time efficiency without sacrificing diagnostic accuracy. PMID:25680356

  6. Cardiac MRI findings of endomyocardial fibrosis (Loeffler's endocarditis) in a patient with rheumatoid arthritis.

    Science.gov (United States)

    Kharabish, Ahmed; Haroun, Dina

    2015-04-01

    Loeffler's endocarditis and cardiac manifestations of the hypereosinophilic syndrome (HES) are rare and difficult to diagnose. We report a case of in a 36 year-old female with a history of rheumatoid arthritis with disabling dyspnea. The transthoracic echocardiogram demonstrated normal systolic cardiac functions and a left ventricular apical thrombus. However, using cardiovascular magnetic resonance (CMR) with inversion-recovery (IR) delayed enhancement, and cine steady-state free precession (SSFP) sequences, we were able to clearly demonstrate endocardial fibrosis, tissue inflammation, apical ventricular hypertrophy, and LV thrombus that correlate with clinical findings. We believe cardiac MRI is more useful than transthoracic echocardiography in the diagnosis and management of HES and ultimately it obviated the need for biopsy to confirm the diagnosis. PMID:25870507

  7. Free-Breathing 3D Imaging of Right Ventricular Structure and Function Using Respiratory and Cardiac Self-Gated Cine MRI.

    Science.gov (United States)

    Zhu, Yanchun; Liu, Jing; Weinsaft, Jonathan; Spincemaille, Pascal; Nguyen, Thanh D; Prince, Martin R; Bao, Shanglian; Xie, Yaoqin; Wang, Yi

    2015-01-01

    Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV). Right ventricular (RV) morphology and function are also important for the diagnosis of cardiopulmonary diseases and serve as predictors for the long term outcome. The purpose of this study is to develop a self-gated free-breathing 3D imaging method for RV quantification and to evaluate its performance by comparing it with breath-hold 2D cine imaging in 7 healthy volunteers. Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%. High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89). Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. In conclusion, the proposed self-gated free-breathing 3D cardiac cine imaging technique provides comparable image quality and correlated functional measurements to those acquired with the multiple breath-hold 2D technique in RV. PMID:26185764

  8. MRI and radiographic findings in Currarino's triad

    International Nuclear Information System (INIS)

    Currarino's triad is a rare complex of a congential sacral bony abnormality, anorectal malformation and a presacral mass. Intractable constipation since birth is the leading symptom of this triad, which follows an autosomal dominant mode of heredity. We report conventional radiographic and MR findings in one family consisting of a mother and her two daughters. In all three cases, radiography revealed an abnormality of the os sacrum, the so-called scimitar sacrum. MR examination, undertaken next in our institution, was applied with T1-, T2- and proton density weighted sequences in all three orientations before and after i.v. application of gadolinium diethylene-triamine-pentaacetic acid (Gd-DTPA). In two patients we were able to diagnose the complete form of the triad and in one patient an incomplete form. In any case of a radiographically diagnosed scimitar sacrum in combination with constipation. Currarino's triad should be considered. MRI, as the method of choice, should be the next step to detect a presacral mass and any anomalies of the spinal canal. The importance of early recognition lies in the high morbidity and mortality rates resulting from this disorder. (orig.)

  9. MRI findings in little leaguer's shoulder

    International Nuclear Information System (INIS)

    Little leaguer's shoulder, a stress injury of the proximal humeral physis, should be considered in the differential diagnosis for an adolescent baseball player with shoulder pain, especially if the player is pitching regularly in a competitive environment. While roentgenographs may or may not be helpful, depending on the duration and severity of the injury, we report the MRI appearance of a case of little leaguer's shoulder. We found MRI helpful in diagnosing injury to the growth plate that was radiographically occult; furthermore, we were able to document the patient's progress with a follow-up MRI examination, which showed improvement with treatment. (orig.)

  10. Unilateral moya-moya disease: MRI findings

    International Nuclear Information System (INIS)

    The term 'moya-moya' refers to hypertrophic collateral circulation in the basal ganglia, in patients with stenosis or occlusion of the distal internal carotid artery at its bifurcation. Recent reports stress the value of MRI in the demonstration of both collateral circulation and cerebral infarction in patients with moya-moya disease. We wish to report a case of MRI demonstration of unilateral moya-moya vessels in a 10-year-old child. (orig.)

  11. MRI findings in thoracic outlet syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Aralasmak, Ayse; Sharifov, Rasul; Kilicarslan, Rukiye; Alkan, Alpay [Bezmialem Vakif University, Department of Radiology, Fatih/Istanbul (Turkey); Cevikol, Can; Karaali, Kamil; Senol, Utku [Akdeniz University, Department of Radiology, Antalya (Turkey)

    2012-11-15

    We discuss MRI findings in patients with thoracic outlet syndrome (TOS). A total of 100 neurovascular bundles were evaluated in the interscalene triangle (IS), costoclavicular (CC), and retropectoralis minor (RPM) spaces. To exclude neurogenic abnormality, MRIs of the cervical spine and brachial plexus (BPL) were obtained in neutral. To exclude compression on neurovascular bundles, sagittal T1W images were obtained vertical to the longitudinal axis of BPL from spinal cord to the medial part of the humerus, in abduction and neutral. To exclude vascular TOS, MR angiography (MRA) and venography (MRV) of the subclavian artery (SA) and vein (SV) in abduction were obtained. If there is compression on the vessels, MRA and MRV of the subclavian vessels were repeated in neutral. Seventy-one neurovascular bundles were found to be abnormal: 16 arterial-venous-neurogenic, 20 neurogenic, 1 arterial, 15 venous, 8 arterial-venous, 3 arterial-neurogenic, and 8 venous-neurogenic TOS. Overall, neurogenic TOS was noted in 69%, venous TOS in 66%, and arterial TOS in 39%. The neurovascular bundle was most commonly compressed in the CC, mostly secondary to position, and very rarely compressed in the RPM. The cause of TOS was congenital bone variations in 36%, congenital fibromuscular anomalies in 11%, and position in 53%. In 5%, there was unilateral brachial plexitis in addition to compression of the neurovascular bundle. Severe cervical spondylosis was noted in 14%, contributing to TOS symptoms. For evaluation of patients with TOS, visualization of the brachial plexus and cervical spine and dynamic evaluation of neurovascular bundles in the cervicothoracobrachial region are mandatory. (orig.)

  12. Tarsal coalitions: CT and MRI findings

    International Nuclear Information System (INIS)

    Objective: Tarsal coalition is a rare congenital disorder which represents the abnormal fusion of two or more tarsal bones. The purpose of this paper is to describe our experience with CT and MR in this articular disorder, helping to improve its diagnosis, which in many cases is missed. It is most often diagnosed when the tarsal region is examined for other reasons, than as a confirmation of a preliminary clinical diagnosis. Material and Method: Between January 1999 and May 2001, we studied 16 cases of tarsal coalitions, with CT and/or MR. A helical Toshiba K-press tomograph, a conventional TC 60-X tomograph (performing reconstruction algorithms with bone filter, and 2 mm sections per 2 mm of bed displacement) and a 1.5 Tessla Toshiba Visart MR equipment (axial, sagittal and coronal planes, with T1, T2-weighted, and T2 with fat suppression sequences) were used. Results: In the 16 cases evaluated, 28 tarsal coalitions were detected. Eight patients had bilateral coalitions (50%) and of the 8 remaining patients with unilateral disorders, 4 had 4 coexistent coalitions (25%). Eight bony bars were detected (28.5%) and 20 were non-ossified-cartilaginous and/or fibrous- (71.5%); 14 of them (50%) were talo-calcaneal, 8 (28.5%) were calcaneo-navicular, 4 (14.2%) were talo-navicular and 2 (7.1%) were cuboid-navicular coalitions. Conclusion: Calcaneo-navicular and talo-calcaneal coalitions account for approximately 80% of all cases. Conventional radiology is usually the initial method to study these lesions and often allows to make the diagnosis without the need for more complex methods. When the radiological findings are non-existent or misleading, CT or MRI may lead to a final diagnosis: to differentiate among the various subtypes and to assess the degree of articular involvement, which is mandatory in order to define the appropriate treatment. (author)

  13. MRI findings in thoracic outlet syndrome

    International Nuclear Information System (INIS)

    We discuss MRI findings in patients with thoracic outlet syndrome (TOS). A total of 100 neurovascular bundles were evaluated in the interscalene triangle (IS), costoclavicular (CC), and retropectoralis minor (RPM) spaces. To exclude neurogenic abnormality, MRIs of the cervical spine and brachial plexus (BPL) were obtained in neutral. To exclude compression on neurovascular bundles, sagittal T1W images were obtained vertical to the longitudinal axis of BPL from spinal cord to the medial part of the humerus, in abduction and neutral. To exclude vascular TOS, MR angiography (MRA) and venography (MRV) of the subclavian artery (SA) and vein (SV) in abduction were obtained. If there is compression on the vessels, MRA and MRV of the subclavian vessels were repeated in neutral. Seventy-one neurovascular bundles were found to be abnormal: 16 arterial-venous-neurogenic, 20 neurogenic, 1 arterial, 15 venous, 8 arterial-venous, 3 arterial-neurogenic, and 8 venous-neurogenic TOS. Overall, neurogenic TOS was noted in 69%, venous TOS in 66%, and arterial TOS in 39%. The neurovascular bundle was most commonly compressed in the CC, mostly secondary to position, and very rarely compressed in the RPM. The cause of TOS was congenital bone variations in 36%, congenital fibromuscular anomalies in 11%, and position in 53%. In 5%, there was unilateral brachial plexitis in addition to compression of the neurovascular bundle. Severe cervical spondylosis was noted in 14%, contributing to TOS symptoms. For evaluation of patients with TOS, visualization of the brachial plexus and cervical spine and dynamic evaluation of neurovascular bundles in the cervicothoracobrachial region are mandatory. (orig.)

  14. CINE CLUB

    CERN Multimedia

    Ciné Club

    2009-01-01

    Main Auditorium CERN jeudi 17 décembre 2009 à 18 h 15 à l’Amphithéâtre principal du CERN (bâtiment 500)   Comme chaque année avant Noël, le CineClub du CERN est heureux d’inviter petits et grands à une projection gratuite du film   LE MONDE DE NEMO (FINDING NEMO) (USA, 2003, Andrew Stanton and Lee Unkrich)   Dans les eaux tropicales de la Grande Barrière de corail, un poisson-clown du nom de Marin mène une existence paisible avec son fils unique, Nemo. Redoutant l’océan et ses risques imprévisibles, il fait de son mieux pour protéger son fils. Comme tous les petits poissons de son âge, celui-ci rêve pourtant d’explorer les mystérieux récifs. Lorsque Nemo disparaît, Marin devient malgré lui le héros d’une qu&a...

  15. CT and MRI findings of ameloblastoma in two cases

    International Nuclear Information System (INIS)

    We report CT and MRI findings in two patients with ameloblastoma. One case had a multilocular mixed lesion and the other had a unilocular solid pattern. The second case is probably one of the youngest reported. CT and MRI can be used to delineate and show the extent of the tumour. (orig.)

  16. CT and MRI findings of ameloblastoma in two cases

    Energy Technology Data Exchange (ETDEWEB)

    Cihangiroglu, M.; Akfirat, M.; Yildirim, H. [Department of Radiology, Firat University School of Medicine, Elazig (Turkey)

    2002-05-01

    We report CT and MRI findings in two patients with ameloblastoma. One case had a multilocular mixed lesion and the other had a unilocular solid pattern. The second case is probably one of the youngest reported. CT and MRI can be used to delineate and show the extent of the tumour. (orig.)

  17. Non-traumatic peroneal nerve palsy: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J.Y. [Departments of Radiology St Vincent' s Hospital, Catholic University of Korea, Paldal-gu, Suwon city, Gyeonggi-do (Korea, Republic of); Ihn, Y.K. [Departments of Radiology St Vincent' s Hospital, The Catholic University of Korea, Paldal-gu, Suwon city, Gyeonggi-do (Korea, Republic of)]. E-mail: Ihn@catholic.ac.kr; Kim, J.S. [Department of Rehabilitation medicine, St Vincent' s Hospital, The Catholic University of Korea, Paldal-gu, Suwon city, Gyeonggi-do (Korea, Republic of); Chun, K.A. [Department of Radiology, Uijeongbu St. Mary' s Hospital, The Catholic University of Korea, Geumo-dong, Uijeongbu city, Gyeonggi-do (Korea, Republic of); Sung, M.S. [Department of Radiology, Holy Family Hospital, The Catholic University of Korea, Sosa-dong, Wonmi-gu, Bucheon city, Gyeonggi-do (Korea, Republic of); Cho, K.H. [Department of Radiology, College of Medicine, Yeungnam Univ. Medical Center, Nam-gu, Daegu (Korea, Republic of)

    2007-01-15

    Aim: To present magnetic resonance imaging (MRI) findings of non-traumatic peroneal nerve palsy and to evaluate the usefulness of MRI in patients with non-traumatic peroneal nerve palsy. Materials and methods: In a retrospective study, 11 consecutive patients presenting with peroneal nerve palsy were included. MR images of the lower leg and electrophysiological examinations were also reviewed. The cause of peroneal nerve palsy was determined on the basis of MRI findings and was evaluated using electrophysiological data. Nine patients with causative lesions detected on MRI, underwent surgery. Results: Clinical examination and electromyography (EMG) disclosed 11 peroneal lesions. MRI and EMG revealed three types of signal intensity change, i.e. deep peroneal nerve palsy type, common peroneal nerve palsy type, and superficial peroneal nerve palsy type. The MRI and EMG findings were in agreement in seven (65%) of the 11 study patients. In nine patients the causative lesions were identified using MRI, including ganglion cyst (n = 6), osteochondroma (n = 1), synovial cyst (n = 1), and aneurysm (n = 1). Conclusion: Ganglion cyst is the most common cause of non-traumatic peroneal nerve palsy. MRI offers a noninvasive method for obtaining useful information to assess, localize, and monitor peripheral peroneal nerve palsy.

  18. MRI findings of intracranial cystic meningiomas

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, D. [Department of Radiology, XinQiao Hosptial, Third Military Medical University, ChongQing 400037 (China); Hu, L.-B. [Department of Radiology, Second People' s Hospital of ChongQing, ChongQing (China); Zhen, J.W. [Department of Radiology and Biomedical Engineering, University of California, San Francisco, CA 94143 (United States); Zou, L.-G. [Department of Radiology, XinQiao Hosptial, Third Military Medical University, ChongQing 400037 (China); Feng, X.-Y. [Department of Radiology, HuaShan Hosptial, Medical Center of FuDan University, ShangHai (China); Wang, W.-X. [Department of Radiology, XinQiao Hosptial, Third Military Medical University, ChongQing 400037 (China); Wen, L. [Department of Radiology, XinQiao Hosptial, Third Military Medical University, ChongQing 400037 (China)], E-mail: cqzdwl@yahoo.com.cn

    2009-08-15

    Aim: To report the magnetic resonance imaging (MRI) features of intracranial cystic meningiomas and compare these features in intra- and peritumoural cyst groups. Materials and methods: Fourteen cases of peritumoural cystic meningiomas were compared with 18 cases of intratumoural cystic meningiomas. All patients were examined using non-enhanced and contrast-enhanced MRI. Tumour location, tumour size, signal intensity, enhancement characteristics, and cystic changes were assessed. The MRI features were compared between the intra- and peritumoural cyst groups. Results: Most cystic meningiomas comprised two or more cysts. The solid parts of the tumours showed moderate or marked enhancement after the injection of contrast material. An enhanced cyst wall was found in six out of 14 cases in the peritumoural cyst group, but not in the intratumoural cyst group. Peritumoural cystic meningiomas were predominately located in the cerebral falx, whereas the intratumoural cystic meningiomas were predominantly found in frontal convexity (X{sup 2} = 7.434, p = 0.024). The cysts were larger in the peritumoural cyst group than in the intratumoural cyst group (t = 5.274, p = 0.0258). Peritumoural oedema was more commonly found in the intratumoural cyst group (X{sup 2} = 6.863, p = 0.008). Cystic meningiomas with solid parts located inside the cyst are reported for the first time. Conclusion: Cystic meningiomas, although uncommon, should be differentiated from other cystic intracranial lesions. Peri- and intratumoural cystic meningiomas have distinct MRI features. The present study provides the first report of two lesions with solid parts located inside the cyst, as well as one lesion with a calcified solid nodule and haemorrhage within the cyst.

  19. CT and MRI findings of sinonasal hemangiopericytoma

    International Nuclear Information System (INIS)

    Objective: To determine the CT and MRI features of the sinonasal cavity. Methods: The CT and MRI of nine patients with histologically proved hemangiopericytoma in the sinonasal cavity were retrospectively reviewed. All nine patients underwent CT and seven of them underwent MRI. In addition, the time-intensity curve (TIC) of dynamic contrast-enhanced (DCE) MRI were analyzed in three patients. Results: The lesions were from the nasal cavity in 5 cases, the maxillary sinus in 3 cases, and the sphenoid sinus in one case. The lesions appeared spindle in 4 cases, oval in 3, and irregular in 2. The mean maximum diameter of the lesions was 31 mm (range, 15 to 52 mm). Seven hemangiopericytomas had well- defined margins and 2 had ill-defined margins. On plain CT, the lesions were isodense to gray matter in six (66.7%) and slightly hyperdense in three (33.3%) patients. Only two patients had post-contrast CT and the tumors showed marked enhancement. The lesions caused adjacent bony compression and absorption in 7 cases and bony destruction in 2. On MR T1WI, hemangioperieytomas appeared hypointense in 3 (42.8%) patients and isointense in 4 (57.2%) patients. On T2WI, the lesions appeared hyperintense in three (42.8%) patients and isointense in four (57.2%) patients. On T1WI, all the lesions showed relatively homogeneous signal, while 2 lesions revealed heterogeneous signal on T2WI. Hemangiopericytomas showed marked homogeneous contrast enhancement in 4 cases and heterogeneous contrast enhancement in 3. TIC showed a steady enhancement pattern in 3 patients. The lesions involved the orbit in 2 cases and, cavernous sinus, anterior skull base meninge, pterygopalatine fossa and infratemporal fossa in one case. Five patients underwent follow-up for two to eight years after surgery. Two patients were found to have recurrence. Conclusions: Marked enhancement and steady enhancement pattern of TIC on MRI are typical manifestations of hemangiopericytoma of the sinonasal cavity. Bone changes may help to identify the nature of the lesion. Imaging can accurately detect the scope of hemangiopericytoma in this region. (authors)

  20. MRI findings in chronic relapsing inflammatory optic neuropathy

    OpenAIRE

    Sharma, Ankush; Khurana, Dheeraj; Kesav, Praveen

    2013-01-01

    Chronic relapsing inflammatory optic neuropathy is a steroid responsive recurrent optic neuropathy. We describe a patient who presented with recurrent episodes of painful visual loss over a period of 19?years and atypical findings on cranial MRI.

  1. Solitary infantile choriocarcinoma of the liver: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Hoef, Marianne van der; Willi, Ulrich V.; Huisman, Thierry A.G.M. [University Children' s Hospital Zurich, Department of Diagnostic Imaging, Zurich (Switzerland); Niggli, Felix K. [University Children' s Hospital Zurich, Department of Paediatrics, Zurich (Switzerland)

    2004-10-01

    Infantile hepatic choriocarcinoma is a rare, highly malignant germ-cell tumour believed to result from a choriocarcinoma of the placenta that spreads to the child. Most infants present with a characteristic clinical picture of anaemia, hepatomegaly and precocious puberty. Imaging findings, including conventional MRI, may be non-specific. To improve the accuracy of diagnosis, we present the imaging findings of contrast-enhanced dynamic MRI in a 4.5-month-old boy with infantile hepatic choriocarcinoma. (orig.)

  2. MRI findings of fetal cleft lip and palate

    International Nuclear Information System (INIS)

    Objective: To investigate the MR findings of fetal cleft lip (CL) and evaluate the advantages and limitations of MRI in the diagnosis. Methods: Twelve pregnant women suspicious of fetal CL/cleft palate (CP) on ultrasonography were enrolled in the study. The findings of ultrasonography, MRI and following-up were compared. Results: MRI and ultrasonography detected 12 fetuses with CL/CP. The following-up results showed 1 case with incomplete cleft lip and the other 11 cases with complete cleft lips and cleft palates. MRI and unltrasonography were consistent with the follow-up in CL detection, showing completed or uncompleted soft tissue interruption of the fetal lips with amniotic fluid filling which is high signal on T2WI. On MRI, CP showed discontinuous of the soft tissue which were interrupted by long T2 signal and communicating with oral cavity ad nasal cavity. MRI missed 1 case and excluded 1 case of CP. Ultrasonography predicted 5 case of CL, excluded 1 CP but missed 6 cases. The accuracy, sensitivity and specificity in detection CL/CP was 91.7% (11/12), 90.9% (10/11), 100% (1/1) for MRI and 50.0% (6/12), 45.5% (5/11), 100% (1/1) for ultrasonography, respectively. Conclusion: MR imaging had advantage over ultrasonography in detecting CP, MRI is an essential when CP is suspicious on ultrasonography. (authors)

  3. Functional cine MRI of the abdomen for the assessment of implanted synthetic mesh in patients after incisional hernia repair: initial results

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Tanja [Ludwig-Maximilians-University Munich, Department of Clinical Radiology, Munich (Germany); Ludwig-Maximilians-University Munich, Department of Clinical Radiology, Klinikum Innenstadt, Munich (Germany); Ladurner, Roland; Mussack, Thomas [Ludwig-Maximilians-University Munich, Department of Surgery and Traumatology, Klinikum Innenstadt, Munich (Germany); Gangkofer, Alexander; Reiser, Maximilian; Lienemann, Andreas [Ludwig-Maximilians-University Munich, Department of Clinical Radiology, Munich (Germany)

    2007-12-15

    The aim of our study was to develop a method that allows the vizualiation and evaluation of implanted mesh in patients after incisional hernia repair with MRI. Furthermore, we assessed problems typically related with mesh implantation like adhesions and muscular atrophy. We enrolled 28 patients after incisional hernia repair. In 10 patients mesh implantation was done by laparoscopy (expanded polytetrafluoroethylene=ePTFE mesh) and in 18 by laparotomy (polypropylene mesh). Functional MRI was performed on a 1.5-T system in supine position. Sagittal and axial TrueFISP images of the entire abdomen were acquired with the patient repeatedly straining. Evaluation included: correct position and intact fixation of the mesh, furthermore visceral adhesions, recurrent hernia and atrophy of the rectus muscle. The ePTFE mesh was visible in all cases; the polypropylene mesh was not detectable. In seven of the ten ePTFE meshes the fixation was not intact; two recurrent hernias were detected. Twenty of 28 patients had intraabdominal adhesions. In 5 cases mobility of the abdominal wall was reduced, and 16 patients showed an atropy of the rectus muscle. Functional cine MRI is a suitable method for follow-up studies in patients after hernia repair. ePTFE meshes can be visualized directly, and typical complications like intestinal adhesions and abdominal wall dysmotility can be assessed reliably. (orig.)

  4. Functional cine MRI of the abdomen for the assessment of implanted synthetic mesh in patients after incisional hernia repair: initial results

    International Nuclear Information System (INIS)

    The aim of our study was to develop a method that allows the vizualiation and evaluation of implanted mesh in patients after incisional hernia repair with MRI. Furthermore, we assessed problems typically related with mesh implantation like adhesions and muscular atrophy. We enrolled 28 patients after incisional hernia repair. In 10 patients mesh implantation was done by laparoscopy (expanded polytetrafluoroethylene=ePTFE mesh) and in 18 by laparotomy (polypropylene mesh). Functional MRI was performed on a 1.5-T system in supine position. Sagittal and axial TrueFISP images of the entire abdomen were acquired with the patient repeatedly straining. Evaluation included: correct position and intact fixation of the mesh, furthermore visceral adhesions, recurrent hernia and atrophy of the rectus muscle. The ePTFE mesh was visible in all cases; the polypropylene mesh was not detectable. In seven of the ten ePTFE meshes the fixation was not intact; two recurrent hernias were detected. Twenty of 28 patients had intraabdominal adhesions. In 5 cases mobility of the abdominal wall was reduced, and 16 patients showed an atropy of the rectus muscle. Functional cine MRI is a suitable method for follow-up studies in patients after hernia repair. ePTFE meshes can be visualized directly, and typical complications like intestinal adhesions and abdominal wall dysmotility can be assessed reliably. (orig.)

  5. MRI findings in an adolescent with type I citrullinaemia

    International Nuclear Information System (INIS)

    Citrullinaemia is a rare inborn error of urea cycle metabolism. We describe the MRI findings in a 16-year-old boy with type I citrullinaemia during an episode of acute hyperammonaemic encephalopathy and compare them to his previous follow-up MRI studies. MRI revealed bilateral high signal intensity in the cingulate, perirolandic, parietal and temporoinsular cortex, the subcortical white matter and left thalamus. Diffusion-weighted imaging showed high signal intensity and low apparent diffusion coefficient values in the frontoparietal lobes. To our knowledge, MRI findings in an adolescent with type I citrullinaemia have not been previously reported. Since our patient's neuroradiological findings showed greater similarity to type II citrullinaemia, we think his brain injury during this acute episode was probably age-related and independent of the type of citrullinaemia. (orig.)

  6. Pathological findings correlated with MRI in HIV infection

    International Nuclear Information System (INIS)

    MRI forms an important part of the assessment of patients with HIV-related disease presenting with cerebral symptoms. Eleven formalin-fixed brains were studied at 0.5 T using T2- and T1-weighted sequences. In two cases of progressive multifocal leucoencephalopathy and one case each of toxoplasmosis and lymphoma, the extent of white matter abnormality seen on MRI corresponded broadly with that on pathological examination. In general, however, histological changes were more frequent than lesions on MRI. Cases in wich abnormalities were not seen with standard MRI included those with multiple tuberculous granulomata, multinucleate giant cells, microglial nodules, perivascular cuffing and cytomegalovirus inclusions. A common finding on MRI was punctate or patchy high signal in the basal ganglia on T2-weighted scans, seen in six cases. Corresponding histological changes included calcification of vessels with widened perivascular spaces, and mineralised neurones. (orig.)

  7. Postoperative findings in MRI following pituitary surgery

    International Nuclear Information System (INIS)

    36 patients with pituitary adenomas were examined via MRI to describe physiological changes and to visualise a residual tumour. Pre- and postoperative examinations included T1- and T2-weighted SE sequences. T1-weighted images were obtained in sagittal and coronal orientation pre- and post-Gd-DTPA application and T2-weighted images in coronal orientation. In 12 cases a residual tumour was found. Its signal intensity and contrast enhancement were similar to those of the primary tumour. Implanted material could be distinguished by localisation, decrease in volume and different signal intensity. The behaviour of contrast enhancement was helpful, since implanted material showed a rim enhancement. In our experience a sensitive imaging protocol in the follow-up of operated pituitary adenomas would be an early examination three months postoperatively followed by a control examination after one year. Information on the size and localisation of the primary tumour and the performed operative procedure is essential. (orig.)

  8. Membranous lipodystrophy: skeletal findings on CT and MRI

    Energy Technology Data Exchange (ETDEWEB)

    Nwawka, O.K.; Schneider, Robert; Mintz, Douglas N. [Hospital for Special Surgery, Department of Radiology and Imaging, New York, NY (United States); Bansal, Manjula [Hospital for Special Surgery, Department of Pathology and Laboratory Medicine, New York, NY (United States); Lane, Joseph [Hospital for Special Surgery, Department of Orthopedic Surgery, New York, NY (United States)

    2014-10-15

    Membranous lipodystrophy, also known as Nasu-Hakola disease, is a rare hereditary condition with manifestations in the nervous and skeletal systems. The radiographic appearance of skeletal lesions has been well described in the literature. However, CT and MRI findings of lesions in the bone have not been documented to date. This report describes the radiographic, CT, MRI, and histopathologic skeletal findings in a case of membranous lipodystrophy. With corroborative pathologic findings, a diagnosis of membranous lipodystrophy on imaging allows for appropriate clinical management of disease manifestations. (orig.)

  9. Renal MRI findings and their clinical associations in nephropathia epidemica: analysis of quantitative findings

    Energy Technology Data Exchange (ETDEWEB)

    Paakkala, A. [University of Tampere, Medical School, Tampere (Finland); Tampere University Hospital, Department of Radiology, Tampere (Finland); Dastidar, P.; Ryymin, P. [Tampere University Hospital, Department of Radiology, Tampere (Finland); Huhtala, H. [University of Tampere, School of Public Health, Tampere (Finland); Mustonen, J. [University of Tampere, Medical School, Tampere (Finland); Tampere University Hospital, Department of Medicine, Tampere (Finland)

    2005-05-01

    Morphologic renal magnetic resonance imaging (MRI) findings in patients with nephropathia epidemica (NE) were evaluated, and these findings were correlated with the clinical course of NE. Renal MRI was performed in 20 hospitalized NE patients during the acute phase of their disease. A repeat MRI study was made 5-8 months later. Renal parenchymal volume, renal length and parenchymal thickness were decreased in all patients in the repeat study. Edema/fluid collections were found bilaterally in 16 patients in the primary MRI study. Greater change in parenchymal volume, renal length and parenchymal thickness between the primary and the repeat MRI study as well as the presence of edema/fluid collections in the primary study evinced mild association with clinical fluid volume overload, high blood pressure level, inflammation, thrombocytopenia and severe clinical renal insufficiency. Change in parenchymal volume was associated with a severe clinical course more markedly than the other MRI findings. Measurable renal MRI changes occurred in every NE patient. The severity of the findings in MRI evinced mild association with clinical fluid volume overload, high blood pressure level, inflammation, thrombocytopenia and severe clinical renal insufficiency. Based on this study and our previous ultrasound (US) findings, we prefer US as the primary examination mode in NE patients. (orig.)

  10. Measurement of coronary flow response to cold pressor stress in asymptomatic women with cardiovascular risk factors using spiral velocity-encoded cine MRI at 3 Tesla

    International Nuclear Information System (INIS)

    Background: Coronary sinus (CS) flow in response to a provocative stress has been used as a surrogate measure of coronary flow reserve, and velocity-encoded cine (VEC) magnetic resonance imaging (MRI) is an established technique for measuring CS flow. In this study, the cold pressor test (CPT) was used to measure CS flow response because it elicits an endothelium-dependent coronary vasodilation that may afford greater sensitivity for detecting early changes in coronary endothelial function. Purpose: To investigate the feasibility and reproducibility of CS flow reactivity (CSFR) to CPT using spiral VEC MRI at 3 Tesla in a sample of asymptomatic women with cardiovascular risk factors. Material and Methods: Fourteen asymptomatic women (age 38 years ± 10) with cardiovascular risk factors were studied using 3D spiral VEC MRI of the CS at 3 T. The CPT was utilized as a provocative stress to measure changes in CS flow. CSFR to CPT was calculated from the ratio of CS flow during peak stress to baseline CS flow. Results: CPT induced a significant hemodynamic response as measured by a 45% increase in rate-pressure product (P<0.01). A significant increase in CS volume flow was also observed (baseline, 116 ± 26 ml/min; peak stress, 152 ± 34 ml/min, P=0.01). CSFR to CPT was 1.31 ± 0.20. Test-retest variability of CS volume flow was 5% at baseline and 6% during peak stress. Conclusion: Spiral CS VEC MRI at 3 T is a feasible and reproducible technique for measuring CS flow in asymptomatic women at risk for cardiovascular disease. Significant changes in CSFR to CPT are detectable, without demanding pharmacologic stress

  11. Muscle hernias of the lower leg: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Mellado, J.M. [Radiology Department, Hospital Virgen de la Cinta, Tortosa, Tarragona (Spain)]|[IDI - Centre Tarragona, Ressonancia Magnetica, Hospital Joan XXIII, Tarragona (Spain); Perez del Palomar, L. [Radiology Department, Hospital Virgen de la Cinta, Tortosa, Tarragona (Spain)

    1999-08-01

    Muscle hernias of the lower leg involving the tibialis anterior, peroneus brevis, and lateral head of the gastrocnemius were found in three different patients. MRI findings allowed recognition of herniated muscle in all cases and identification of fascial defect in two of them. MR imaging findings and the value of dynamic MR imaging is emphasized. (orig.) With 3 figs., 10 refs.

  12. Synovial Hemangioma in the Knee: MRI Findings

    Directory of Open Access Journals (Sweden)

    Harun Arslan

    2015-01-01

    Full Text Available Synovial hemangiomas are rare benign tumors of vascular origin. A 23-year-old boy presented with knee pain and swelling. The boy had developed symptoms 18-months earlier. He was diagnosed with synovial hemangioma based on magnetic resonnance imaging examination and histopathologic findings of the arthroscopic biopsy tissue. We present the magnetic resonance imaging and histopathologic findings of synovial hemangioma of the knee.

  13. Clinical and MRI Findings in Acute Cerebellitis

    OpenAIRE

    Alkan, Özlem; TAN, Meliha; Yusuf Ziya DEM?RO?LU; Tokmak, Naime; ?enay DEM?R; Tülin YILDIRIM

    2009-01-01

    Acute cerebellitis is an inflammatory syndrome characterized by cerebellar dysfunction with acute onset. Here, the clinical findings, conventional and diffusion-weighted MR imaging features of five cases are reported. The most common clinical findings were headache, vertigo, nausea and vomiting. Neurological examination revealed cerebellar ataxia, nystagmus, dysmetria and dysdiadokinesia. Analysis of the CSF showed an elevated protein content and pleocytosis. Bilateral cerebellar cortical inv...

  14. The value of MRI findings in augmented mammoplasty

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Sang Wook; Oh, Ki Keun; Jung, Eun Ki; Kim, Ji Hyung [Yonsei University College of Medicine, Seoul (Korea, Republic of)

    1995-04-15

    The objective of augmentation mammography includes reconstruction and cosmesis after breast surgery. Increasing frequency of the procedure has been related with increased complications. Authors evaluated the value of breast MRI in the diagnosis of complications after augmentation mammoplasty. Authors studied 42 breasts of 24 patients, who had undertaken augmentation mammoplasty. We evaluated findings of mammography, ultrasonography, and breast MRI in all patients. We used variable MRI sequences for better evaluation of implant status. The results were compared with the findings in surgical field. In all imaging studies, nodule or mass was identifiable in the cases of interstitial paraffine injection (8 breasts), interstitial silicon injection (7 breasts), and herb medication (2 breasts). However, the differentiation between malignant and benign nodule was only possible at dynamic breast MRI. Mammogram was not helpful in the evaluation of extracapsular rupture in the cases of silastic bag insertion. In sonogram, identification of echogenic material was possible, although, false negative and false positive rate were high. MRI was able to visualize contour of entire implant and it was able to easily recognize low signal internal structure. MRI was the most accurate diagnostic tool in the evaluation of the character of the palpable mass after augmentation mammoplasty and early detection of breast implant rupture.

  15. The value of MRI findings in augmented mammoplasty

    International Nuclear Information System (INIS)

    The objective of augmentation mammography includes reconstruction and cosmesis after breast surgery. Increasing frequency of the procedure has been related with increased complications. Authors evaluated the value of breast MRI in the diagnosis of complications after augmentation mammoplasty. Authors studied 42 breasts of 24 patients, who had undertaken augmentation mammoplasty. We evaluated findings of mammography, ultrasonography, and breast MRI in all patients. We used variable MRI sequences for better evaluation of implant status. The results were compared with the findings in surgical field. In all imaging studies, nodule or mass was identifiable in the cases of interstitial paraffine injection (8 breasts), interstitial silicon injection (7 breasts), and herb medication (2 breasts). However, the differentiation between malignant and benign nodule was only possible at dynamic breast MRI. Mammogram was not helpful in the evaluation of extracapsular rupture in the cases of silastic bag insertion. In sonogram, identification of echogenic material was possible, although, false negative and false positive rate were high. MRI was able to visualize contour of entire implant and it was able to easily recognize low signal internal structure. MRI was the most accurate diagnostic tool in the evaluation of the character of the palpable mass after augmentation mammoplasty and early detection of breast implant rupture

  16. Neonatal asphyxia: early MRI findings and its correlation with prognosis

    International Nuclear Information System (INIS)

    Objective: To investigate the early MRI findings of neonatal asphyxia and its correlation with prognosis. Methods: Early MRI findings of neonatal asphyxia in 80 cases and follow-up MRI findings in 26 cases were reviewed retrospectively. Results: Fifteen patients had normal MR findings (group A), and the remaining 65 patients were divided into four groups based on patterns of injury: small area of brain edema in 12 cases (group B); streak-like and spotty hyperintensities in 8 cases on T1WI (group C); large area of brain edema in 12 cases (group D); and mixed injury pattern in 33 cases (group E). Follow-up MRI scans in group A (3 cases), B (5 cases) and C(5 cases) were performed, and only 1 case in group C showed abnormalities. Follow-up scans in 4 cases of group D revealed abnormalities, and 7 out of 9 cases in group E found abnormalities. Conclusion: MRI can show the brain damage in asphyxiated neonates objectively during the first week of life, and estimate the prognosis at the early stage

  17. Intracranial inflammatory pseudotumors : MRI and CT findings

    International Nuclear Information System (INIS)

    The purpose of this study was to describe the MR imaging and CT findings of intracranial inflammatory pseudotumors. We reviewed the MR imaging (n=8) and CT (n=4) studies of eight patients (M:F=4:4, mean age:41 years) with pathologically proven intracranial inflammatory pseudotumor. The findings were then evaluated with regard to location, shape, MR signal intensity, CT density and degree of contrast enhancement of the lesion, surrounding parenchymal edema, adjacent bone change and the location of accompanying extracranial lesion. In two patients, the parietal convexity was involved unilaterally, with no extracranial mass, and in the other six, the middle cranial fossa was involved unilaterally and extracranial mass was present. The lesion also involved the tentorium in four cases, the cavernous sinus in four, the anterior cranial fossa in one, and the posterior cranial fossa in one. The location of extracranial mass was the mastoid and middle ear cavity in two cases, the infratemporal fossa in two, both the infratemporal fossa and paranasal sinuses in one, and the orbit in one. MR images showed diffuse dural thickening in all eight cases, leptomeningeal thickening in four, and focal meningeal-based mass in two. As seen on T1-weighted images, the lesions were isointense to gray matter in eight cases, and on T2-weighted images were hypointense in seven cases and isointense in one. Marked homogeneous contrast enhancement was seen in all eight cases. The lesions seen on brain CT, performed in two cases, were isodense. Adjacent brain parenchymal edema and the destruction of adjacent bones were each seen in five cases. The characteristic MR findings of intracranial inflammatory pseudotumors are(1) diffuse dural thickening;(2) a focal meningeal-based mass which on T2-weighted images is seen as hypointense;and marked(3) contrast enhancement : these findings are, however, nonspecific. In order to differentiate these tumors, an awareness of these findings is, however, useful

  18. Reliability of MRI findings in candidates for lumbar disc prosthesis

    International Nuclear Information System (INIS)

    Limited reliability data exist for localised magnetic resonance imaging (MRI) findings relevant to planning of treatment with lumbar disc prosthesis and later outcomes. We assessed the reliability of such findings in chronic low back pain patients who were accepted candidates for disc prosthesis. On pretreatment MRI of 170 patients (mean age 41 years; 88 women), three experienced radiologists independently rated Modic changes, disc findings and facet arthropathy at L3/L4, L4/L5 and L5/S1. Two radiologists rerated 126 examinations. For each MRI finding at each disc level, agreement was analysed using the kappa statistic and differences in prevalence across observers using a fixed effects model. All findings at L3/L4 and facet arthropathy at L5/S1 had a mean prevalence <10% across observers and were not further analysed, ensuring interpretable kappa values. Overall interobserver agreement was generally moderate or good (kappa 0.40-0.77) at L4-S1 for Modic changes, nucleus pulposus signal, disc height (subjective and measured), posterior high-intensity zone (HIZ) and disc contour, and fair (kappa 0.24) at L4/L5 for facet arthropathy. Posterior HIZ at L5/S1 and severely reduced subjective disc height at L4/L5 differed up to threefold in prevalence between observers (p < 0.0001). Intraobserver agreement was mostly good or very good (kappa 0.60-1.00). In candidates for disc prosthesis, mostly moderate interobserver agreement is expected for localised MRI findings. (orig.)

  19. Reliability of MRI findings in candidates for lumbar disc prosthesis

    Energy Technology Data Exchange (ETDEWEB)

    Berg, Linda; Espeland, Ansgar [Haukeland University Hospital, Department of Radiology, Bergen (Norway); University of Bergen, Section for Radiology, Department of Surgical Sciences, Bergen (Norway); Neckelmann, Gesche [Haukeland University Hospital, Department of Radiology, Bergen (Norway); Gjertsen, Oeivind [Oslo University Hospital, Department of Neuroradiology, Oslo (Norway); Hellum, Christian [Oslo University Hospital, Department of Orthopaedics, Oslo (Norway); University of Oslo, Department of Orthopaedics, Oslo (Norway); Johnsen, Lars G. [University Hospital of Trondheim, National Centre for Diseases of the Spine, Trondheim (Norway); University Hospital of Trondheim, Orthopaedic Department, Trondheim (Norway); Eide, Geir E. [Haukeland University Hospital, Centre for Clinical Research, Bergen (Norway); University of Bergen, Department of Public Health and Primary Health Care, Bergen (Norway)

    2012-07-15

    Limited reliability data exist for localised magnetic resonance imaging (MRI) findings relevant to planning of treatment with lumbar disc prosthesis and later outcomes. We assessed the reliability of such findings in chronic low back pain patients who were accepted candidates for disc prosthesis. On pretreatment MRI of 170 patients (mean age 41 years; 88 women), three experienced radiologists independently rated Modic changes, disc findings and facet arthropathy at L3/L4, L4/L5 and L5/S1. Two radiologists rerated 126 examinations. For each MRI finding at each disc level, agreement was analysed using the kappa statistic and differences in prevalence across observers using a fixed effects model. All findings at L3/L4 and facet arthropathy at L5/S1 had a mean prevalence <10% across observers and were not further analysed, ensuring interpretable kappa values. Overall interobserver agreement was generally moderate or good (kappa 0.40-0.77) at L4-S1 for Modic changes, nucleus pulposus signal, disc height (subjective and measured), posterior high-intensity zone (HIZ) and disc contour, and fair (kappa 0.24) at L4/L5 for facet arthropathy. Posterior HIZ at L5/S1 and severely reduced subjective disc height at L4/L5 differed up to threefold in prevalence between observers (p < 0.0001). Intraobserver agreement was mostly good or very good (kappa 0.60-1.00). In candidates for disc prosthesis, mostly moderate interobserver agreement is expected for localised MRI findings. (orig.)

  20. MRI findings of complete growth hormone deficiency

    International Nuclear Information System (INIS)

    Magnetic resonance (MR) imaging was performed on the pituitary gland of 20 children (age range, 2-11 years) with short stature due to growth hormone deficiency. Sixteen patients with multiple pituitary hormone deficiency showed disappearance of the pituitary stalk, disappearance of high signal area of the posterior pituitary, presence of ectopic pituitary, and decreased volume of the anterior pituitary. Many of them had a history of perinatal abnormalities such as asphyxia at delivery, breech delivery, and bradytocia. On the contrary, patients with isolated growth hormone deficiency presented no abnormal findings on MR images, and had no history of perinatal abnormalities. The findings of pituitary stalk separation syndrome suggested the presence of multiple hypopituitarism. (S.Y.)

  1. MRI findings of complete growth hormone deficiency

    Energy Technology Data Exchange (ETDEWEB)

    Ichiba, Yozo [National Hospital of Okayama (Japan)

    1995-10-01

    Magnetic resonance (MR) imaging was performed on the pituitary gland of 20 children (age range, 2-11 years) with short stature due to growth hormone deficiency. Sixteen patients with multiple pituitary hormone deficiency showed disappearance of the pituitary stalk, disappearance of high signal area of the posterior pituitary, presence of ectopic pituitary, and decreased volume of the anterior pituitary. Many of them had a history of perinatal abnormalities such as asphyxia at delivery, breech delivery, and bradytocia. On the contrary, patients with isolated growth hormone deficiency presented no abnormal findings on MR images, and had no history of perinatal abnormalities. The findings of pituitary stalk separation syndrome suggested the presence of multiple hypopituitarism. (S.Y.).

  2. Investigation of MRI findings of Tolosa-Hunt syndrome

    International Nuclear Information System (INIS)

    Objective: To investigate Mill findings of Tolosa-Hunt syndrome and evaluate the role of MRI in diagnosis and differential diagnosis. Methods: Seventeen cases of Tolosa-Hunt syndrome, confirmed by clinical follow-up, were studied. MRI scanning of the brain and thin-slice MilI scanning of the cavernous sinus combined with contrast scanning were performed and compared with each other in all cases. Results: Enlarged cavernous sinus was found in thin-slice MRI combined with contrast scanning in all 17 cases, which showed isointense or mildly hypointense on both T1-weighted and T2-weighted images and markedly homogeneous enhancement on postcontrast T1-weighted imaging. Thin-slice MRI also showed the abnormalities of the superior orbital fissure in three cases, of the orbital apex in one case, and of both the superior orbital fissure and the orbital apex in three cases. Cavernous sinus segment of the internal carotid artery, encircled by the lesion was seen in six patients and localized narrowing of it was observed in four eases. However, abnormal appearances of the cavernous sinus were demonstrated in only eleven patients on MRI scanning of the brain. Therefore, thin-slice Mill combined with contrast scanning was superior to Mill scanning of the brain in evaluation of Tolosa-Hunt syndrome (?2=4.17, P<0.05). Conclusion: Compared with MRI scanning of the brain, thin-slice MRI scanning of the cavernous sinus combined with contrast scanning could better reveal the characteristic findings of Tolosa-Hunt syndrome, contributing to diagnosis and differential diagnosis as well as follow-up. (authors)

  3. Useful MRI findings for differential diagnosis of sublingual mass lesions

    International Nuclear Information System (INIS)

    The purpose of this study is to identify useful MRI findings for differentiating sublingual mass lesions. MR images of 29 patients with sublingual swelling were retrospectively reviewed. Patients were categorized into 4 groups according to their final diagnoses: cysts, benign tumors, inflammation and malignant tumors. Clinical symptoms and MRI findings of the patients in each diagnostic category were investigated. Of 29 patients, 6 had benign tumors, 6 had ranula, 6 had inflammation, 11 had malignant tumors. Eighteen patients (62%) were correctly diagnosed as one of 4 disease categories by clinical findings alone. Signal intensity of lesions compared to the muscle and the normal sublingual space (SLS) was not characteristic for any of the diagnostic categories. Only ranulas showed homogenous signal intensity within the lesion on T2 images. Hemangiomas were easily diagnosed by the characteristic contour and architecture including flow void. All lesions with ragged boundaries were either inflammatory or malignant masses. The lesions with ragged boundaries accompanied by expansion of the SLS were inflammatory masses. The lesions with smooth boundaries and a capsule-like rim were either cysts or benign tumors. Utilizing these MRI findings, 25 of 29 patients (86%) were correctly categorized into one of 4 diagnostic categories. Four lesions without a capsule-like rim confined within SLS could not be correctly categorized. These were 2 cases of inflammatory mass and 2 cases of malignant salivary gland tumor. MRI findings were efficient for differentiation of sublingual mass lesions. However, some cases of malignant salivary gland tumor originating from the sublingual gland could not be differentiated on MRI findings from cases of chronic inflammation. (author)

  4. White matter changes in Leber's hereditary optic neuropathy: MRI findings.

    Science.gov (United States)

    Küker, W; Weir, A; Quaghebeur, G; Palace, J

    2007-05-01

    Leber's hereditary optic neuropathy is a mitochondrial disorder causing bilateral optic nerve degeneration. It is sometimes associated with clinical signs of multiple sclerosis. We report MRI findings in two patients with LHON-MS and comment on possible distinguishing features of this disease entity. PMID:17437624

  5. White matter changes in Leber's hereditary optic neuropathy: MRI findings.

    OpenAIRE

    Küker, W; Weir, A; Quaghebeur, G; Palace, J.

    2007-01-01

    Leber's hereditary optic neuropathy is a mitochondrial disorder causing bilateral optic nerve degeneration. It is sometimes associated with clinical signs of multiple sclerosis. We report MRI findings in two patients with LHON-MS and comment on possible distinguishing features of this disease entity.

  6. Accuracy of MRI findings in chronic lateral ankle ligament injury: Comparison with surgical findings

    International Nuclear Information System (INIS)

    Aim: To evaluate the accuracy of magnetic resonance imaging (MRI) findings in chronic lateral ankle ligament injury in comparison with that of surgical findings. Materials and methods: Forty-eight cases (25 men, 23 women, mean age 36 years) of clinically suspected chronic ankle ligament injury underwent MRI studies and surgery. Sagittal, coronal, and axial, T1-weighted, spin-echo, proton density and T2-weighted, fast spin-echo images with fat saturation were obtained in all patients. MRI examinations were read in consensus by two fellowship-trained academic musculoskeletal radiologists who evaluated the lateral ankle ligaments, including the anterior talofibular ligament (ATFL) and calcaneofibular ligament (CFL) without clinical information. The results of the MRI studies were then compared with the surgical findings. Results: The MRI findings of ATFL injury showed a sensitivity of detection of complete tears of 75% and specificity of 86%. The sensitivity of detection of partial tears was 75% and the specificity was 78%. The sensitivity of detection of sprains was 44% and the specificity was 88%. Regarding the MRI findings of CFL injury, the sensitivity of detection of complete tears was 50% and the specificity was 98%. The sensitivity of detection of partial tear was 83% and the specificity was 93%. The sensitivity of detection of sprains was 100% and the specificity was 90%. Regarding the ATFL, the accuracies of detection were 88, 58, 77, and 85% for no injury, sprain, partial tear, and complete tear, respectively, and for the CFL the accuracies of detection were 90, 90, 92, and 96% for no injury, sprain, partial tear, and complete tear, respectively. Conclusions: The diagnosis of a complete tear of the ATFL on MRI is more sensitive than the diagnosis of a complete tear of the CFL. MRI findings of CFL injury are diagnostically specific but are not sensitive. However, only normal findings and complete tears were statistically significant between ATFL and CFL (p < 0.001).

  7. MRI Findings of Brucellar Spondylitis: A Case Report

    International Nuclear Information System (INIS)

    Brucellosis is a systemic infectious disease, and musculoskeletal involvement is a frequent complication. Particularly, spondylitis is a common involvement. However, early diagnosis of brucellar spondylitis is often difficult due to non-specific clinical symptoms and long latent period. Especially in Korea, where tuberculosis is an endemic disease, differentiation between tuberculous and brucellar spondylitis is clinically and radiologically more challenging. A 59-year-old male cattle farmer, who presented with non-specific back pain, had spondylitis on magnetic resonance imaging (MRI), and serologic test finally confirmed brucellar spondylitis. Therefore, we report a case of a rather rare disease in Korea, brucellar spondylitis with a review of MRI findings.

  8. MRI Findings of Intrinsic and Extrinsic Duodenal Abnormalities and Variations.

    Science.gov (United States)

    Dusunceli Atman, Ebru; Erden, Ayse; Ustuner, Evren; Uzun, Caglar; Bektas, Mehmet

    2015-01-01

    This pictorial review aims to illustrate the magnetic resonance imaging (MRI) findings and presentation patterns of anatomical variations and various benign and malignant pathologies of the duodenum, including sphincter contraction, major papilla variation, prominent papilla, diverticulum, annular pancreas, duplication cysts, choledochocele, duodenal wall thickening secondary to acute pancreatitis, postbulbar stenosis, celiac disease, fistula, choledochoduodenostomy, external compression, polyps, Peutz-Jeghers syndrome, ampullary carcinoma and adenocarcinoma. MRI is a useful imaging tool for demonstrating duodenal pathology and its anatomic relationships with adjacent organs, which is critical for establishing correct diagnosis and planning appropriate treatment, especially for surgery. PMID:26576112

  9. Necrotizing fasciitis: unreliable MRI findings in the preoperative diagnosis

    International Nuclear Information System (INIS)

    The authors present two cases of necrotizing fasciitis (NF), one case of dermatomyositis and one case of posttraumatic muscle injury, which have similar magnetic resonance imaging findings in terms of skin, subcutaneous fat, superficial and deep fasciae and muscle involvement. These cases highlight the need for cautious interpretation of magnetic resonance imaging (MRI) findings, for they are nonspecific and the preoperative decision should be based mostly on the evolution of the clinical status

  10. Necrotizing fasciitis: unreliable MRI findings in the preoperative diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Arslan, Arzu E-mail: arzuarslan@netscape.net; Pierre-Jerome, Claude; Borthne, Arne

    2000-12-01

    The authors present two cases of necrotizing fasciitis (NF), one case of dermatomyositis and one case of posttraumatic muscle injury, which have similar magnetic resonance imaging findings in terms of skin, subcutaneous fat, superficial and deep fasciae and muscle involvement. These cases highlight the need for cautious interpretation of magnetic resonance imaging (MRI) findings, for they are nonspecific and the preoperative decision should be based mostly on the evolution of the clinical status.

  11. Spongiform leucoencephalopathy after inhaling heroin vapor: CT and MRI findings

    International Nuclear Information System (INIS)

    Objective: To explore CT and MRI features of spongiform leucoencephalopathy after inhaling 'heroin' pyrolysate, and to improve the diagnostic ability of the disease. Methods: Four patients, which inhaled heroin vapor, received the CT or MRI pre- and post-contrast scanning. MR sequences included conventional SE T1WI, T2WI, fluid attenuation inverse recover (FLAIR), and MRS. Results: All 4 cases had similar symmetrical lesions involving the cerebellum, lateral brainstem, cerebral peduncles, posterior limbs of internal capsule, splenium of corpus callosum, medial lemniscuses, and posterior cerebral white mattes without enhancement. The lesions showed hypodense on CT and hypointense on T1WI, hyperintense on T2WI and FLAIR. Cerebellar lesions were more serious than cerebral one, and the parieto-occipital lesions were serious than frontal one. MRS showed that the abnormalities in the white matter were degenerative changes, not necrosis. Conclusion: CT and MRI findings of this diseases are characteristic. Combined with the history, the disease can be diagnosed

  12. MRI findings and correlative study of MRI and visual evoked potentials in optic neuritis

    International Nuclear Information System (INIS)

    Objective: To investigate the effective MRI sequences and describe the correlation between MRI and visual evoked potential (VEP) in diagnosing optic neuritis. Methods: One hundred and fifty-four eyes with visual impairment of 98 patients with diagnoses of optic neuritis, papillitis, multiple sclerosis and Devic's disease underwent MRI and VEP examination. The MRI findings were analyzed and correlated with VEP results and clinical presentation by using X2 test, wilco xon test and Kappa test. Results Out of the 154 sick eyes, 56 eyes presented thickened optic nerves, 76 eyes had normal diameter of the optic nerve, and 22 eyes had thin optic nerves. A total of 132 optic nerves showed abnormally high signal in STIR sequences, including involvement of intraocular segment in 7, intraorbital segment in 1.35, intracanalicular segment in 109, intracranial segment in 97, optic chiasm in 56, and optic tract in 23. A total of 54 patients underwent postcontrast MRI. Seventy-four optic nerves of 87 eyes showed enhancement. Among the 196 eyes of 98 patients, 132 eyes presented visual impairment and simultaneous abnormal MR signal of the optic nerve, and 26 eyes had both normal vision and normal MR signal of optic nerve. The consistency of MRI findings and vision status was 80. 61% (Kappa 0.453,P1-weighted MR sequence combined with fat- suppression are helpful in diagnosis of optic neuritis. VEP is helpful in diagnosing optic neuritis and in finding subclinical visual problem. The MRI combined with VEP could improve the diagnostic accuracy of optic neuritis. (authors)

  13. Nodular fasciitis: correlation of MRI findings and histopathology

    International Nuclear Information System (INIS)

    Objective: To compare the histopathology of nodular fasciitis (NF) with the magnetic resonance imaging (MRI) findings in order to evaluate the basis of the MR signal characteristics. Design and patients: Ten patients with NF, nine females and 1 male, with an age ranging from 13 to 58 years (mean 26.8 years) were studied. MRI findings, available in all 10 patients, were compared with the histopathology in nine patients, and an area-to-area comparative study of the whole specimen section histopathology and MRI was performed in two patients. Results: On the basis of an excisional biopsy or resection specimen, the nine lesions were classified into myxoid (n=4), cellular (n=3) and fibrous (n=2) subtypes. Four myxoid lesions with a subcutaneous location showed a homogeneous SI comparable with muscle on T1-weighted images, high SI on T2-weighted images, and had homogeneous enhancement. One cellular lesion presented with homogeneous, slightly higher SI than muscle on T1-weighted images and inhomogeneous, high SI on T2-weighted images. Alcian blue stain of the whole specimen section revealed the lesion had two parts corresponding to different enhancement patterns on MRI. The blue-stained myxoid part showed markedly diffuse enhancement, while the non-stained cystic space had only peripheral enhancement. Two other cellular lesions had the same appearance on both T1- and T2-weighted images and showed inhomogeneous, diffuse enhancement. One fibrous subtype lesion presented with inhomogeneous, overall slightly higher SI than muscle on T1-weighted images, lower SI at the periphery and high SI in the center on STIR images and only peripheral enhancement. Microscopy and CD-31 staining of the lesion showed more extracellular matrix, with poor vascularity in the center and more collagenous matrix with higher vascularity at the periphery. Conclusion: Although similar findings were found in some lesions, the large histologic variability of NF hampers the definition of a prototype of NF on MRI. However, the MRI appearance of the myxoid subtype is rather characteristic. Histologic findings reflect the different SI characteristics and enhancement pattern on MRI. (orig.)

  14. Nodular fasciitis: correlation of MRI findings and histopathology

    Energy Technology Data Exchange (ETDEWEB)

    Wang, X.L.; De Schepper, A.M.A.; Vanhoenacker, F.; Gielen, J. [Department of Radiology, University Hospital Antwerp (Belgium); De Raeve, H. [Department of Pathology, University Hospital Antwerp, Edegem (Belgium); Aparisi, F. [Department of Magnetic Resonance Imaging, Clinica Virgen del Consuelo, Valencia (Spain); Rausin, L. [Department of Radiology, Centre Hospitalier Regional de la Citadelle, Liege (Belgium); Somville, J. [Department of Orthopedics, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem (Belgium)

    2002-03-01

    Objective: To compare the histopathology of nodular fasciitis (NF) with the magnetic resonance imaging (MRI) findings in order to evaluate the basis of the MR signal characteristics. Design and patients: Ten patients with NF, nine females and 1 male, with an age ranging from 13 to 58 years (mean 26.8 years) were studied. MRI findings, available in all 10 patients, were compared with the histopathology in nine patients, and an area-to-area comparative study of the whole specimen section histopathology and MRI was performed in two patients. Results: On the basis of an excisional biopsy or resection specimen, the nine lesions were classified into myxoid (n=4), cellular (n=3) and fibrous (n=2) subtypes. Four myxoid lesions with a subcutaneous location showed a homogeneous SI comparable with muscle on T1-weighted images, high SI on T2-weighted images, and had homogeneous enhancement. One cellular lesion presented with homogeneous, slightly higher SI than muscle on T1-weighted images and inhomogeneous, high SI on T2-weighted images. Alcian blue stain of the whole specimen section revealed the lesion had two parts corresponding to different enhancement patterns on MRI. The blue-stained myxoid part showed markedly diffuse enhancement, while the non-stained cystic space had only peripheral enhancement. Two other cellular lesions had the same appearance on both T1- and T2-weighted images and showed inhomogeneous, diffuse enhancement. One fibrous subtype lesion presented with inhomogeneous, overall slightly higher SI than muscle on T1-weighted images, lower SI at the periphery and high SI in the center on STIR images and only peripheral enhancement. Microscopy and CD-31 staining of the lesion showed more extracellular matrix, with poor vascularity in the center and more collagenous matrix with higher vascularity at the periphery. Conclusion: Although similar findings were found in some lesions, the large histologic variability of NF hampers the definition of a prototype of NF on MRI. However, the MRI appearance of the myxoid subtype is rather characteristic. Histologic findings reflect the different SI characteristics and enhancement pattern on MRI. (orig.)

  15. A study of brain MRI findings in children with epilepsy

    International Nuclear Information System (INIS)

    Magnetic resonance imaging in the brain was performed in 293 patients with childhood-onset (<15 y.o.) epilepsy who had been classified into 4 groups, idiopathic localization-related epilepsy (ILRE), 78 patients; idiopathic generalized epilepsy (IGE), 116 patients; symptomatic localization-related epilepsy (SLRE), 68 patients and symptomatic generalized epilepsy (SGE), 31 patients, with the Classification of Epilepsies and Epileptic Syndrome (1989 International League Against Epilepsy). The examination was performed with a 1.5 T magnet. One hundred twenty-five patients (42.7%) showed abnormal findings, and the incidence in each group was as follows: Idiopathic epilepsy: The rate of abnormal findings in the ILRE and IGE groups was 21.8% and 20.7%, respectively. Most of the abnormal findings were secondary changes, such as diffuse or localized brain atrophy. Of the congenital abnormalities, the main finding was arachnoid cyst. Symptomatic epilepsy: The rate of abnormality in the SLRE patients was 88.2%, and 85% of the findings were secondary changes, i.e., brain atrophy, or degeneration of the white matter. In the SGE group, the rate was 77.4%, with an almost equal percentage of congenital and secondary changes. Of 255 patients who were examined by electroencephalography (EEG) on the same day as MRI, about 50% showed a correlation between the EEG records and the MRI abnormalities. However, only 8 patients showed a correlation in localization between the EEG and MRI abnormalities. (author)

  16. Hypereosinophilic syndrome with hepatic involvement : US, CT and MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Cha, Sang Hoon [Ansan Hospital, Korea Univ. College of Medicine, Seoul (Korea, Republic of); Park, Cheol Min; Seol, Hae Young; Cha, In Ho [Guro hospital, Korea Univ. College of Medicine, Seoul (Korea, Republic of); Kim, Hee Jin [Kyunghee Pundang Cha General Hospital, Seoul (Korea, Republic of); Lee, Dong Ho [Kyunghee Univ. hospital, Seoul (Korea, Republic of); Baek, Seung Yeon [Ewha Womans Univ. Mokdong Hospital, Seoul (Korea, Republic of); Kim, Pyo Nyun; Ha, Hyun Kwon [Asan Medical Center, Ulsan Univ. College of Medicine, Seoul (Korea, Republic of)

    1996-10-01

    To evaluate the findings of US, CT and MRI in the hepatic involvement of hypereosinophilic syndrome. We reviewed imaging findings of hypereosinophilic syndrome with hepatic involvement in nine patients. Imaging studies were US(n=9), conventional CT(CCT, n=6), dynamic incremental CT(DICT, n=3), and MRI with conventional spin-echo sequence(MRI-CSE, n=3). For DICT, we obtained images of the early arterial phase(n=1), portal venous phase(n=3) and the late venous phase(n=3). T1WI were obtained with 600-700 msec/13-17msec(TR/TE) and T2WI were obtained with 1850-2300 msec/80-90 msec(n=3). Gadolinium-enhanced T1WI were also obtained(n=2). US showed multiple hypoechoic or isoechoic nodules(7/9) and appeared normal(2/9). CCT showed multiple hypodense nodules(5/6) and appeared normal(1/6). DICT showed patchy, multiple hypodense nodules and showed hepatic nodules during the portal venous phase only(3/3). MRI-CSE showed one to several focal high-signal nodules on T2WI and subtle low-signal nodules on T1WI(2/3), and showed several subtle high-signal lesions on Gd-enhanced T1WI(1/2) and appeared normal on T1, T2WI(1/3). Hepatic involvement of hypereosinophilic syndrome showed varied imaging findings on US, CT and MRI.

  17. Hypereosinophilic syndrome with hepatic involvement : US, CT and MRI findings

    International Nuclear Information System (INIS)

    To evaluate the findings of US, CT and MRI in the hepatic involvement of hypereosinophilic syndrome. We reviewed imaging findings of hypereosinophilic syndrome with hepatic involvement in nine patients. Imaging studies were US(n=9), conventional CT(CCT, n=6), dynamic incremental CT(DICT, n=3), and MRI with conventional spin-echo sequence(MRI-CSE, n=3). For DICT, we obtained images of the early arterial phase(n=1), portal venous phase(n=3) and the late venous phase(n=3). T1WI were obtained with 600-700 msec/13-17msec(TR/TE) and T2WI were obtained with 1850-2300 msec/80-90 msec(n=3). Gadolinium-enhanced T1WI were also obtained(n=2). US showed multiple hypoechoic or isoechoic nodules(7/9) and appeared normal(2/9). CCT showed multiple hypodense nodules(5/6) and appeared normal(1/6). DICT showed patchy, multiple hypodense nodules and showed hepatic nodules during the portal venous phase only(3/3). MRI-CSE showed one to several focal high-signal nodules on T2WI and subtle low-signal nodules on T1WI(2/3), and showed several subtle high-signal lesions on Gd-enhanced T1WI(1/2) and appeared normal on T1, T2WI(1/3). Hepatic involvement of hypereosinophilic syndrome showed varied imaging findings on US, CT and MRI

  18. Cine phase-contrast MRI measurement of CSF flow in the cervical spine: a pilot study in patients with spinal cord injury

    Science.gov (United States)

    Negahdar, MJ; Shakeri, M.; McDowell, E.; Wells, J.; Vitaz, T.; Harkema, S.; Amini, A.

    2011-03-01

    MRI velocimetry (also known as phase-contrast MRI) is a powerful tool for quantification of cerebrospinal fluid (CSF) flow in various regions of the brain and craniospinal junction and has been accepted as a diagnostic tool to assist with the diagnosis of certain conditions such as hydrocephalus and chiari malformations. Cerebrospinal fluid is continually produced in the ventricles of the brain, flows through the ventricular system and then out and around the brain and spinal cord and is reabsorbed over the convexity of the brain. Any disease process which either impedes the normal pattern of flow or restricts the area where flow occurs can change the pattern of these waveforms with the direction and velocity of flow being determined by the pressure transmitted from the pulsation of the heart and circulation of blood within the central nervous system. Therefore, we hypothesized that phase-contrast MRI could eventually be used as a diagnostic aid in determining the degree of spinal cord compression following injury to the cervical or thoracic spine. In this study, we examined CSF flow in 3 normal subjects and 2 subjects with non-acute injuries in the cervical spine using Cine phasecontrast MRI. CSF flow analysis was performed using an in-house developed software. The flow waveform was calculated in both normal subjects (n=3) as well as subjects with spinal cord injury in the cervical spine (n=2). The bulk flow at C2 was measured to be 0.30 +/- 0.05 cc, at 5 cm distal to C2, it was 0.19+/- 0.07 cc, and at 10 cm distal to C2, it was 0.17+/- 0.05 cc. These results were in good agreement with previously published results. In patients with spinal cord injury, at the site of injury in the cervical spine, bulk flow was found to be 0.08 +/- 0.12 cc, at 5 cm proximal to the site of injury it was found to be 0.18 +/- 0.07 cc, and at 5 cm distal to the site of injury, it was found to be 0.12 +/- 0.01 cc.

  19. Feasibility of high-dose dobutamine stress SSFP cine MRI at 3 tesla with patient adaptive local RF shimming using dual-source RF transmission. Initial results

    International Nuclear Information System (INIS)

    To investigate the feasibility of high-dose dobutamine stress (HDDS) imaging using SSFP sequences at 3 T employing patient-adaptive local RF-shimming using a dual-source RF transmission system. 13 Patients underwent a HDDS protocol on a 3 T MRI scanner (Achieva 3.0T-TX, Philips Healthcare), equipped with a dual-source RF transmission system. SSFP cine sequences using patient-adaptive local RF-shimming (RF-S) were compared to cine images acquired without additional shimming. Image quality was evaluated on a 4-point grading scale and number of non-diagnostic segments assessed. Contrast (CN) between myocardium (SIM) and blood pool (SIB) was calculated [(SIB-SIM)/(SIB+SIM)]. Image quality both at rest and maximum stress was significantly improved with RF-S (ED:3.56 ± 0.5 vs. 3.23 ± 0.63; ES:3.4 ± 0.5 vs. 3.1 ± 0.7) compared to no RF-S (ED:2.9 ± 0.72 vs. 2.15 ± 0.78; ES:2.64 ± 0.74 vs. 1.95 ± 0.76; p < 0.01). The amount of non-diagnostic segments was significantly reduced when using RF-S at rest and stress (3 vs. 39; 19 vs. 78, p < 0.05). All HDDS studies were diagnostic if performed with RF-S (n = 13/13) in comparison to conventional shimming (n = 5/13). Image contrast was improved for SSFP sequences with RF-S (0.53 ± 0.08) compared to conventional images (0.46 ± 0.09, p = 0.06). Patient-adaptive local RF-shimming using a dual-source RF transmission system allows for reliable SSFP imaging in a clinical high-dose dobutamine stress protocol at 3 T. RF-S significantly improves image quality and reduces the number of non-diagnostic myocardial segments. (orig.)

  20. Feasibility of high-dose dobutamine stress SSFP cine MRI at 3 tesla with patient adaptive local RF shimming using dual-source RF transmission. Initial results

    Energy Technology Data Exchange (ETDEWEB)

    Strach, K. [Bonn Univ. (Germany). Radiologische Universitaetsklinik; Magdeburg Univ. (Germany). Klinik fuer Radiologie und Nuklearmedizin; Clauberg, R.; Mueller, A.; Naehle, C.P.; Schild, H.H. [Bonn Univ. (Germany). Radiologische Universitaetsklinik; Wonneberger, U. [Magdeburg Univ. (Germany). Klinik fuer Radiologie und Nuklearmedizin; Kouwenhoven, M.; Gieseke, J.; Thomas, Daniel [Philips Healthcare, Best (Netherlands). MR Clinical Science

    2013-01-15

    To investigate the feasibility of high-dose dobutamine stress (HDDS) imaging using SSFP sequences at 3 T employing patient-adaptive local RF-shimming using a dual-source RF transmission system. 13 Patients underwent a HDDS protocol on a 3 T MRI scanner (Achieva 3.0T-TX, Philips Healthcare), equipped with a dual-source RF transmission system. SSFP cine sequences using patient-adaptive local RF-shimming (RF-S) were compared to cine images acquired without additional shimming. Image quality was evaluated on a 4-point grading scale and number of non-diagnostic segments assessed. Contrast (CN) between myocardium (SIM) and blood pool (SIB) was calculated [(SIB-SIM)/(SIB+SIM)]. Image quality both at rest and maximum stress was significantly improved with RF-S (ED:3.56 {+-} 0.5 vs. 3.23 {+-} 0.63; ES:3.4 {+-} 0.5 vs. 3.1 {+-} 0.7) compared to no RF-S (ED:2.9 {+-} 0.72 vs. 2.15 {+-} 0.78; ES:2.64 {+-} 0.74 vs. 1.95 {+-} 0.76; p < 0.01). The amount of non-diagnostic segments was significantly reduced when using RF-S at rest and stress (3 vs. 39; 19 vs. 78, p < 0.05). All HDDS studies were diagnostic if performed with RF-S (n = 13/13) in comparison to conventional shimming (n = 5/13). Image contrast was improved for SSFP sequences with RF-S (0.53 {+-} 0.08) compared to conventional images (0.46 {+-} 0.09, p = 0.06). Patient-adaptive local RF-shimming using a dual-source RF transmission system allows for reliable SSFP imaging in a clinical high-dose dobutamine stress protocol at 3 T. RF-S significantly improves image quality and reduces the number of non-diagnostic myocardial segments. (orig.)

  1. Brainstem evoked potentials in infantile spasms; Comparison with MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Miyazaki, Masahito; Hashimoto, Toshiaki; Murakawa, Kazuyoshi; Tayama, Masanobu; Kuroda, Yasuhiro (Tokushima Univ. (Japan). School of Medicine)

    1992-08-01

    In ten patients with infantile spasms, brainstem evoked potentials and MRI examinations were performed to evaluate the brainstem involvement. The result of short latency somatosensory evoked potentials (SSEP) following the right median nerve stimulation revealed abnormal findings including the absence or low amplitudes of the waves below wave P3 and delayed central conduction time in 7 of the ten patients. The result of auditory brainstem responses (ABR) revealed abnormal findings including low amplitudes of wave V, prolonged interpeak latency of waves I-V and absence of the waves below wave IV in 5 of the ten patients. The result of the MRI examinations revealed various degrees of the brainstem atrophy in 6 of the ten patients, all of whom showed abnormal brainstem evoked potentials. The result of this study demonstrates that patients with infantile spasms are frequently associated with brainstem dysfunction and raises the possibility that brainstem atrophy might be a cause of infantile spasms. (author).

  2. MRI findings of prolonged post-traumatic sternal pain

    International Nuclear Information System (INIS)

    The objective of this study was to characterize the different causes of prolonged sternal pain following thoracic trauma with involvement of the sternum and to define criteria for sternal nonunion diagnosis using MRI. Five patients with abnormalities of the sternum were evaluated for prolonged sternal pain following thoracic trauma using MRI. MR images were evaluated by two radiologists in consensus. The patients were selected from the radiology database, which included 8 patients with post-traumatic prolonged sternal pain. Two patients (n = 2) revealed a sternal nonunion after sternal fracture. One patient had a sternal fracture with delayed union and minor displacement of the sternal halves. Abnormal signal intensity alterations adjacent to and within the manubrio-sternal joint were evident in 2 patients and considered due to trauma-related changes in the manubrio-sternal joint. The 3 patients who were not included in the study had no abnormalities of the sternum: 1 of them proved to have a well-healed sternal fracture and nonunion of a rib fracture, 1 had subtle Tietze's syndrome, and 1 patient revealed no pathological findings on imaging. Various factors may be responsible for prolonged sternal pain following thoracic trauma, and these can be viewed with MRI. In cases of sternal nonunion there was common fluid-like signal in the fracture interspace between the bony edges, and the bone marrow adjacent to the nonunion showed altered signal intensity. MRI identified sternal nonunion and other trauma-related abnormalities of the sternum following chest trauma. (orig.)

  3. Adenomatoid odontogenic tumor: correlation of MRI with histopathological findings

    International Nuclear Information System (INIS)

    Adenomatoid odontogenic tumor is a rare benign and odontogenic tumor that is frequently misdiagnosed as other odontogenic cysts and tumors on radiographic examination. To acquire additional information of adenomatoid odontogenic tumor, we performed magnetic resonance imagings (MRI) at a case of adenomatoid odontogenic tumor. The lesion was divided between the peripheral portion with a thick circular shape and the central portion with a round shape on the basis of the signal intensity (SI) of MRI. The peripheral portion showed intermediate SI contained multifocal no SI on T1WI, high SI contained multifocal no SI on T2WI, and heterogeneous enhancement on CE-T1WI. These multifocal areas corresponded to the numerous punctate radiopaque foci shown on computed tomography. The central portion showed homogeneous low SI on T1WI, homogeneous very high SI on T2WI, and no enhancement on CE-T1WI. Macroscopic examination revealed the round shaped lesion included one large cystic space correspondent to the central portion with a clear cystic wall correspondent to the peripheral portion on MRI. The MRI features corresponded to the macroscopic findings of the histopathological examination

  4. Adenomatoid odontogenic tumor: correlation of MRI with histopathological findings

    Energy Technology Data Exchange (ETDEWEB)

    Konouchi, Hironobu; Asaumi, Jun-ichi E-mail: asaumi@md.okayama-u.ac.jp; Yanagi, Yoshinobu; Hisatomi, Miki; Kishi, Kanji

    2002-10-01

    Adenomatoid odontogenic tumor is a rare benign and odontogenic tumor that is frequently misdiagnosed as other odontogenic cysts and tumors on radiographic examination. To acquire additional information of adenomatoid odontogenic tumor, we performed magnetic resonance imagings (MRI) at a case of adenomatoid odontogenic tumor. The lesion was divided between the peripheral portion with a thick circular shape and the central portion with a round shape on the basis of the signal intensity (SI) of MRI. The peripheral portion showed intermediate SI contained multifocal no SI on T1WI, high SI contained multifocal no SI on T2WI, and heterogeneous enhancement on CE-T1WI. These multifocal areas corresponded to the numerous punctate radiopaque foci shown on computed tomography. The central portion showed homogeneous low SI on T1WI, homogeneous very high SI on T2WI, and no enhancement on CE-T1WI. Macroscopic examination revealed the round shaped lesion included one large cystic space correspondent to the central portion with a clear cystic wall correspondent to the peripheral portion on MRI. The MRI features corresponded to the macroscopic findings of the histopathological examination.

  5. MRI findings in Duane's ocular retraction syndrome

    International Nuclear Information System (INIS)

    Aim: To investigate the innervation pattern of extra-ocular muscles in patients with clinically diagnosed Duane's ocular retraction syndrome (DRS) using magnetic resonance imaging (MRI). Materials and methods: The study population consisted of 11 patients. Six patients had type I DRS (eight eyes), four patients had type II DRS (five eyes) and one patient had inverse DRS. Images were acquired using a Siemens 3 T MRI system. The type of DRS, corresponding innervation findings, and condition of the affected muscles were evaluated by two experienced neuroradiologists in consensus. Results: All patients with clinically diagnosed DRS type I showed absence of the abducens nerve (CN6), hypoplasia of the superior oblique muscle (SOM), and aberrant innervation of lateral rectus muscle (LRM) by an extra branch of oculomotor nerve (CN3). All patients with type II DRS show dual-innervation of the LRM (by CN6 and an aberrant CN3 branch) and hypoplasia of SOM. The single patient with inverse DRS showed hypoplasia of CN3, the medial rectus muscle (MRM), the inferior rectus muscle (IRM), and the inferior oblique muscle (IOM). Conclusion: Each type of DRS has characteristic MRI appearances. Therefore, MRI is a useful diagnostic tool for the confirmation and classification of suspected cases of DRS

  6. MRI and neurological findings in patients with spinal metastases

    Energy Technology Data Exchange (ETDEWEB)

    Switlyk, M.D.; Hole, K.H.; Knutstad, K. [Department of Radiology and Nuclear Medicine, Oslo University Hospital, Norwegian Radium Hospital, Oslo (Norway)], E-mail: marta.switlyk@radiumhospitalet.no; Skjeldal, S.; Zaikova, O. [Department of Orthopedics, Oslo University Hospital, Norwegian Radium Hospital, Oslo (Norway); Hald, J.K. [Department of Radiology and Nuclear Medicine, Oslo University Hospital, Rikshospitalet, Oslo (Norway); Seierstad, T. [Department of Radiology and Nuclear Medicine, Oslo University Hospital, Norwegian Radium Hospital, Oslo (Norway); Faculty of Health Sciences, Buskerud University College, Drammen (Norway)

    2012-12-15

    Background. Magnetic resonance imaging (MRI) is the recommended primary investigation method for metastatic spinal cord compression (MSCC). Initiating treatment before the development of motor deficits is essential to preserve neurological function. However, the relationship between MRI-assessed grades of spinal metastatic disease and neurological status has not been widely investigated. Purpose. To analyze the association between neurological function and MRI-based assessment of the extent of spinal metastases using two different grading systems. Material and Methods. A total of 284 patients admitted to our institution for initial radiotherapy or surgery for symptomatic spinal metastases were included in the study. Motor and sensory deficits were categorized according to the Frankel classification system. Pre-treatment MRI evaluations of the entire spine were scored for the extent of spinal metastases, presence and severity of spinal cord compression, and nerve root compression. Two MRI-based scales were used to evaluate the degree of cord compression and spinal canal narrowing and relate these findings to neurological function. Results. Of the patients included in the study, 28 were non-ambulatory, 49 were ambulatory with minor motor deficits, and 207 had normal motor function. Spinal cord compression was present in all patients with Frankel scores of B or C, 23 of 35 patients with a Frankel score of D (66%), and 48 of 152 patients with a Frankel score of E (32%). The percentage of patients with severe spinal canal narrowing increased with increasing Frankel grades. The grading according to the scales showed a significant association with the symptoms according to the Frankel scale (P < 0.001). Conclusion. In patients with neurological dysfunction, the presence and severity of impairment was associated with the epidural tumor burden. A significant number of patients had radiological spinal cord compression and normal motor function (occult MSCC)

  7. Imaging Findings of Brain Death on 3-Tesla MRI

    International Nuclear Information System (INIS)

    To demonstrate the usefulness of 3-tesla (3T) magnetic resonance imaging (MRI) including T2-weighted imaging (T2WI), diffusion weighted imaging (DWI), time-of-flight (TOF) magnetic resonance angiography (MRA), T2*-weighted gradient recalled echo (GRE), and susceptibility weighted imaging (SWI) in diagnosing brain death. Magnetic resonance imaging findings for 10 patients with clinically verified brain death (group I) and seven patients with comatose or stuporous mentality who did not meet the clinical criteria of brain death (group II) were retrospectively reviewed. Tonsilar herniation and loss of intraarterial flow signal voids (LIFSV) on T2WI were highly sensitive and specific findings for the diagnosis of brain death (p < 0.001 and < 0.001, respectively). DWI, TOF-MRA, and GRE findings were statistically different between the two groups (p = 0.015, 0.029, and 0.003, respectively). However, cortical high signal intensities in T2WI and SWI findings were not statistically different between the two group (p = 0.412 and 1.0, respectively). T2-weighted imaging, DWI, and MRA using 3T MRI may be useful for diagnosing brain death. However, SWI findings are not specific due to high false positive findings.

  8. MRI findings of central nervous system granulocytic sarcoma (chloroma)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chang Man; Kim, Myung Soon; Kim, Ik Soo; Cho, Kwan Soo [Yonsei Univ. College of Medicine, Wonju (Korea, Republic of)

    1997-03-01

    To characterize MRI findings of central nervous system (CNS) granulocytic sarcoma (chloroma) and to analyse the points which differentiate it from other CNS tumors. We evaluated MRI in six patients with CNS granulocytic sarcoma proven by surgery or bone marrow biopsy (intracranical, one case and spine five cases). A 0.5T superconductive MR machine was used for diagnosis and, axial, coronal and sagittal T1- and T2-weighted spin echo images and Gd-DTPA enhanced T1-weighted images were obtained. We retrospectively analized the location, signal intensity, margin, contrast enhancement and homogeneity, and bony change around the tumor. MRI findings of CNS granulocytic sarcomas were as follows : one tumor was seen to be an extra-axial mass in the posterior fossa of the brain, four were epidural, and one was an epidural and presacral masses in the spine;tumor magins were lobulated and three were smooth. On T1-weighted images, all tumors were of isoignal intensity;on T2-weighted images, four were of isosignal intersity and two were of high signal intensity. Contrast enhancement was inhomogeneous in five of six cases. Bony change around the tumor was seen in two cases. On T1-weighted images, CNS granulocytic sarcomas (chloromas) were of isosignal intensity, relative to brain parenchyma or spinal cord;on T2-weighted images, they were of iso or high signal intensity, with relative contrast enhancement. These points could be useful in differentiating them from other CNS tumors.

  9. Cardiac MRI. Diagnostic gain of an additional axial SSFP chest sequence for the detection of potentially significant extracardiac findings in the cardiac MRI examination setting

    Energy Technology Data Exchange (ETDEWEB)

    Roller, F.C.; Schneider, C.; Krombach, G.A. [University Hospital Giessen (Germany). Dept. Radiology; Schuhbaeck, A. [University Hospital Giessen (Germany). Dept. Cardiology; Rolf, A. [Kerckhoff Hospital Bad Nauheim (Germany). Dept. Cardiology

    2014-01-15

    Purpose: Cardiac MRI (CMRI) is an effective method for imaging of the heart. The aim of our study was to assess whether an axial chest sequence in addition to the standard CMR examination setting has advantages in the detection of potentially significant extracardiac findings (PSEF). Materials and Methods: 400 consecutive patients were imaged at 1.5 T for clinical reasons. In addition to the standard long and short-axis views, an axial SSFP sequence was obtained covering the thorax from the lung apex to the diaphragm. All sequences were separately evaluated for PSEF. Results: A total of 25 PSEF were diagnosed in 400 patients, including 16 pleural effusions, a pulmonary fibrosis, a spondylodiscitis, ascites, lymphadenopathies, relapse of a mamma carcinoma, growth of adrenal glands metastases and diaphragmatic elevation. All 25 PSEF were detected by reading survey sequences. 24 of the 25 PSEF were detected by the additional SSFP chest sequence as well as the CINE sequences. Conclusion: In our study the additional axial SSFP chest sequence didn't show a benefit in the detection of PSEF. With the survey sequences we were able to detect all PSEF. We conclude that survey images should be assessed for additional findings. (orig.)

  10. MRI findings of cyclops lesions of the knee

    Scientific Electronic Library Online (English)

    C, Minné; MD, Velleman; FE, Suleman.

    2012-04-01

    Full Text Available Cyclops lesions develop in the anterior aspect of the intercondylar notch typically after anterior cruciate ligament (ACL) reconstruction or injury. It is a lesion consisting of fibrous tissue with or without cartilage and bony components. A cyclops lesion is one of the causes for reduced extension [...] and, in the cases reported here, also knee pain or discomfort after ACL reconstruction. We present the MRI features, particularly the features on proton density weighted turbo spin echo (PDW TSE) and proton density weighted turbo spin echo fat saturation (PDW TSE FS) sequences of four cases of cyclops lesions, and distinguish between the MRI findings of large and small lesions. We also describe a cyclops lesion after a posterior cruciate ligament reconstruction, not described in literature before.

  11. MRI findings of spinal visceral larva migrans of Toxocara canis

    International Nuclear Information System (INIS)

    Purpose: The purpose of this study is to investigate the MRI findings of visceral larva migrans (VLS) of Toxocara canis in spinal cord. Materials and methods: We retrospectively reviewed spinal MRI findings in eight patients with serologically proven Toxocara canis between 2005 and 2008. We evaluated the location, length, extent and migration of the lesion, MR signal intensity (SI), enhancement pattern, and swelling of the spinal cord. We evaluated clinical features including presenting symptoms and signs and treatment response. Results: Total 8 patients (M = 8; age range 36-79 years) were included. The lesions were located in the cervical or thoracic spinal cord in all patients. All lesions showed high SI and minimal or mild swelling of involved spinal cord on T2WI and focal nodular enhancement on posterior or posterolateral segment of spinal cord. The length of involved lesion was relatively short in most patients. There was a migration of lesion in one patient. In spite of albendazole or steroid treatment, neurological symptoms or signs were not significantly improved in all patients. Conclusion: Although all lesions show non-specific imaging findings like non-tumorous myelopathy mimicking transverse myelitis, single lesion, focal nodular enhancement on posterior or posterolateral segment of spinal cord, relatively short segmental involvement and migration of lesion may be characteristic findings of spinal VLM of Toxocara canis. In addition, the reluctant response to the treatment may be characteristic of spinal VLM of Toxocara canis.

  12. MRI findings of spinal visceral larva migrans of Toxocara canis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, In Ho, E-mail: leeinho1974@hanmail.ne [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Department of Radiology, Chungnam National University Hospital, 33 Munhwa-ro, Jung-gu, Daejeon 301-721 (Korea, Republic of); Kim, Sung Tae, E-mail: st7.kim@hotmail.co [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Oh, Dae Kun, E-mail: odk6464@nate.co [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Kim, Hyung-Jin, E-mail: hyungkim@skku.ed [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Kim, Keon Ha, E-mail: somatom@skku.ed [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Jeon, Pyoung, E-mail: drpjeon@gmail.co [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of); Byun, Hong Sik, E-mail: byun5474@skku.ed [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-Gu, Seoul 135-710 (Korea, Republic of)

    2010-08-15

    Purpose: The purpose of this study is to investigate the MRI findings of visceral larva migrans (VLS) of Toxocara canis in spinal cord. Materials and methods: We retrospectively reviewed spinal MRI findings in eight patients with serologically proven Toxocara canis between 2005 and 2008. We evaluated the location, length, extent and migration of the lesion, MR signal intensity (SI), enhancement pattern, and swelling of the spinal cord. We evaluated clinical features including presenting symptoms and signs and treatment response. Results: Total 8 patients (M = 8; age range 36-79 years) were included. The lesions were located in the cervical or thoracic spinal cord in all patients. All lesions showed high SI and minimal or mild swelling of involved spinal cord on T2WI and focal nodular enhancement on posterior or posterolateral segment of spinal cord. The length of involved lesion was relatively short in most patients. There was a migration of lesion in one patient. In spite of albendazole or steroid treatment, neurological symptoms or signs were not significantly improved in all patients. Conclusion: Although all lesions show non-specific imaging findings like non-tumorous myelopathy mimicking transverse myelitis, single lesion, focal nodular enhancement on posterior or posterolateral segment of spinal cord, relatively short segmental involvement and migration of lesion may be characteristic findings of spinal VLM of Toxocara canis. In addition, the reluctant response to the treatment may be characteristic of spinal VLM of Toxocara canis.

  13. Incidental MRI Findings in Patients with Impaired Cognitive Function

    International Nuclear Information System (INIS)

    This study aims to evaluate the incidental findings on brain MRI of patients with cognitive function impairments. We analyzed magnetic resonance (MR) findings of 236 patients with decreased cognitive function. MR protocols include conventional T2 weighted axial images, fluid attenuated inversion recovery axial images, T1 weighted coronal 3-dimensional magnetization-prepared rapid acquisition of gradient echo and diffusion tensor images. We retrospectively evaluated the signal changes that suggest acute/subacute infarction and space occupying lesions which show mass effect. Incidental MR findings were seen in 16 patients. Nine patients (3.8%) showed increased signal intensity on trace map of diffusion tensor images suggesting acute/subacute infarctions. Space occupying lesions were detected in 7 patients, and 3 lesions (1.27%) had mass effect and edema and were considered clinically significant lesions that diminish cognitive functions. Several incidental MR findings were detected in patients with decreased cognitive function, and the incidence of aucte/subacute infarctions were higher. Proper evaluations of MRI in patients with impaired cognitive functions will be helpful in early detection and management of ischemic lesions and space occupying lesions.

  14. Breast Ductal Carcinoma in Situ: Morphologic and Kinetic MRI Findings

    International Nuclear Information System (INIS)

    Adequate diagnosis of ductal carcinoma in situ (DCIS) could lead to efficacious treatment. Due to the fact that DCIS lesions can progress to invasive carcinomas and that the sensitivity of the standard examination – mammography – is between 70 and 80%, use of a more sensitive diagnostic tool was needed. In detection of DCIS, contrast-enhanced magnetic resonance imaging (CE-MRI) has the sensitivity up to 96%. Morphological features and kinetic parameters were evaluated to define the most regular morphological, kinetic and morpho-kinetic patterns on MRI assessment of breast ductal carcinoma in situ (DCIS). We retrospectively assessed eighteen patients with 23 histologically confirmed lesions (mean age, 52.4 ± 10.5 years). All patients were clinically and mammographically examined prior to MRI examination. DCIS appeared most frequently as non-mass-like lesions (12 lesions, 52.17%). The differences in the frequency of lesion types were statistically significant (P<0.05). The following morphological patterns were detected: A: no specific morphologic features, B: linear/branching enhancement, C: focal mass-like enhancement, D: segmental enhancement, E: segmental enhancement in triangular shape, F: diffuse enhancement, G: regional heterogeneous enhancement in one quadrant not conforming to duct distribution and H: dotted or granular type of enhancement with patchy distribution. The difference in the frequency of the proposed patterns was statistically significant (P<0.05). There were eight lesions with mass enhancement, and six with segmental lesions: regional and triangular. There was no statistically significant difference in the frequency of enhancement curve types (P>0.05). There was no significant difference in the frequency of morpho-kinetic patterns. Non-mass-like lesions, lesions with focal or segmental distribution, with a “plateau” enhancement curve type were the most frequent findings of DCIS lesions on MRI

  15. Clinical presentations and MRI findings of angiographically occult vascular malformations

    International Nuclear Information System (INIS)

    Various clinical features as well as MRI findings of AOVM (angiographically occult vascular malformation) were studied. Amongst out patients, since January 1988, there have been 30 cases of symptomatic AOVM (20 males, 10 females) including 4 cases with multiple lesions. The age ranged from 3 to 60 years of age, with a mean of 33.4 years. The locations of symptomatic lesions were in the cerebral hemisphere (15), the thalamus (4), the brain stem (8) and in the cerebellum (3). The initial presentations of these 30 cases were either by hemorrhage (18), convulsive seizure (9) or by progressive neurological deficits (3). The initial presentation was not related to the patient's age and the size of the lesion, but apparently related to the location of AOVM. Most of the lesions in the cerebral hemisphere presented seizures, but all of the lesions in the thalamus, the brain stem and the cerebellum disclosed hemorrhage as an initial presentation. In fact it was noticed that brain stem lesions tend to cause repetitive hemorrhage in a relatively short period. AOVM lesions were clearly visualized with T2-weighted MRI images, consisting of high intensity cores with surrounding low intensity rims. Most of the symptomatic lesions were partially enhanced by Gd-DTPA with varied intensity. Dynamic changes in size and enhancement pattern on MRI were occasionally seen, usually accompanied with episodes such as hemorrhage or neurological deterioration. Although AOVMs were angiographically negative some strands indicating draining veins were observed on MRI in several cases. In contrast, none of the nonsymptomatic lesions (22 lesions) demonstrated enhancement effects with Gd-DTPA. (author)

  16. MRI findings of muscle involvement in idiopathic hypereosinophilic syndrome

    International Nuclear Information System (INIS)

    A 40-year-old white man presented with fever, muscle pain, skin nodules and persistent hypereosinophilia over a period of 1 year. In addition, he had ventricular arrhythmias with episodes of tachycardia. Besides a lack of response to antiparasitic therapy, laboratory and pathological data excluded the diagnosis of trichinosis or any other parasitic infection. The patient's course of the disease over the previous 11/2 years was compatible with hypereosinophilic syndrome. In a muscle biopsy several eosinophilic perivascular and leucocytic intravascular infiltrates were found, indicative of muscle involvement by the disease. This is a report on the MRI findings of muscle involvement in idiopathic hypereosinophilic syndrome. (orig.)

  17. Eosinophilic Otitis Media: CT and MRI Findings and Literature Review

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Won Jung; Lee, Jeong Hyun; Lim, Hyun Kyung; Yoon, Tae Hyun; Cho, Kyung Ja; Baek, Jung Hwan [Asan Medical Center, Ulsan University College of Medicine, Seoul (Korea, Republic of)

    2012-06-15

    Eosinophilic otitis media (EOM) is a relatively rare, intractable, middle ear disease with extremely viscous mucoid effusion containing eosinophils. EOM is associated with adult bronchial asthma and nasal allergies. Conventional treatments for otitis media with effusion (OME) or for chronic otitis media (COM), like tympanoplasty or mastoidectomy, when performed for the treatment of EOM, can induce severe complications such as deafness. Therefore, it should be differentiated from the usual type of OME or COM. To our knowledge, the clinical and imaging findings of EOM of temporal bone are not well-known to radiologists. We report here the CT and MRI findings of two EOM cases and review the clinical and histopathologic findings of this recently described disease entity.

  18. Multidetector CT and MRI findings in periportal space pathologies

    International Nuclear Information System (INIS)

    Periportal region is an anatomic space around portal vein comprising hepatic artery, bile duct, nerves, lymphatics and a potential space. Periportal pathologies may involve any of these structures diffusely or focally with characteristic radiologic findings. Radiologic findings can be helpful in differential diagnosis of pathologies of periportal structures including periportal cavernomatous transformation, hepatic artery aneurysm, biliary diseases, neurofibromatosis, lymphoma, langerhans' cell histiocytosis, periportal fatty infiltration and other causes of periportal halo in adult and pediatric patients. Lobar/segmental intrahepatic involvement can be seen in neurofibromatosis, cavernomatous transformation, fatty infiltration and periportal edema. In this review, we discuss CT and MRI findings of periportal pathologies which can be in the form of diffuse or segmental/lobar involvement

  19. Spirometer-controlled cine magnetic resonance imaging to diagnose tracheobronchomalacia in pediatric patients

    DEFF Research Database (Denmark)

    Ciet, Pierluigi; Wielopolski, Piotr

    2014-01-01

    Tracheobronchomalacia (TBM) is defined as an excessive collapse of the intrathoracic trachea. Bronchoscopy is the gold standard to diagnose TBM, but bronchoscopy has major disadvantages, such as general anaesthesia. Cine-CT is a non-invasive alternative to diagnose TBM, but its use in children is restricted by ionizing radiation. Our aim was to evaluate the feasibility of spirometer-controlled cine-MRI as alternative to cine-CT in a retrospective study.12 children (mean 12 years, range 7-17), suspected to have TBM, underwent cine-MRI. Static scans were acquired at end-inspiration and expiration covering the thorax using a 3D SPGR sequence. 3D-Dynamic-scans were performed covering only the central airways. TBM was defined as a decrease of the trachea or bronchi diameter greater than 50% at end-expiration in the static and dynamic scans.The success rate of the cine-MRI protocol was 92%. Cine-MRI was compared with bronchoscopy or chest-CT in 7 subjects. TBM was diagnosed by cine-MRI in 7 out of 12 children (58%) and was confirmed by bronchoscopy or CT. In 4 patients, cine-MRI demonstrated tracheal narrowing that was not present in the static scans.Spirometer-controlled cine-MRI is a promising technique to assess TBM in children and has the potential to replace bronchoscopy.

  20. MRI findings of uncommon non-hepatocyte origin primary liver tumours with pathological correlation

    OpenAIRE

    Kim, Y.C.; Park, M-S; Chung, Y E; Kim, M-J.; Park, Y. N.; Kang, J-h; Kim, K A; Kim, K.W.

    2010-01-01

    The objective of this article was to illustrate the MRI findings of uncommon non-hepatocyte origin primary liver tumours, correlate them with the pathological features and discuss differential diagnoses. In conclusion, the MRI findings of uncommon benign and malignant non-hepatocyte-origin primary liver tumours vary. Awareness of characteristic MRI features can aid differential diagnosis and prevent unnecessary surgery.

  1. Adult cerebellar medulloblastoma: CT and MRI findings in eight cases

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho Neto, Arnolfo de; Bertoldi, Guilherme A. [Parana Univ., Curitiba, PR (Brazil). Radiologia Diagnostica]. E-mail: arnolfo.carvalho@avalon.sul.com.br; Gasparetto, Emerson L. [Parana Univ., Curitiba, PR (Brazil). Hospital das Clinicas. Secao de Radiologia Diagnostica; Ono, Sergio E. [Parana Univ., Curitiba, PR (Brazil). Faculdade de Medicina; Gomes, Andre F. [Diagnostico Avancado Por Imagem (DAPI), Curitiba, PR (Brazil)

    2003-06-01

    Medulloblastoma is a brain tumor of neuro epithelial origin, which represents 15 to 30% of all pediatric brain tumors, and less than 1% of CNS adult neoplasms. We report the imaging findings of 8 adult patients with medulloblastoma. The mean age was 35 years, ranging from 20 to 65 years, and the male:female rate was 3:5. The tumors were predominantly lateral (63%), hyperdense on CT scans (83%), and on the MRI, hypointense on T1 (100%) and hyperintense on T2 (80%) weighted images. It was seen intratumoral necrosis and cysts in six cases and calcifications in three. Hydrocephalus was observed in 5 cases and brain stem invasion in four. The imaging findings of medulloblastomas in adults are different of those in child, and also nonspecific. Although these tumors are uncommon in adults, they must be considered in the differential diagnosis of cerebellar masses in the posterior fossa of this age group. (author)

  2. Adult cerebellar medulloblastoma: CT and MRI findings in eight cases

    Directory of Open Access Journals (Sweden)

    Carvalho Neto Arnolfo de

    2003-01-01

    Full Text Available Medulloblastoma is a brain tumor of neuroepithelial origin, which represents 15 to 30% of all pediatric brain tumors, and less than 1% of CNS adult neoplasms. We report the imaging findings of 8 adult patients with medulloblastoma. The mean age was 35 years, ranging from 20 to 65 years, and the male:female rate was 3:5. The tumors were predominantly lateral (63%, hyperdense on CT scans (83%, and on the MRI, hypointense on T1 (100% and hyperintense on T2 (80% weighted images. It was seen intratumoral necrosis and cysts in six cases and calcifications in three. Hydrocephalus was observed in 5 cases and brain stem invasion in four. The imaging findings of medulloblastomas in adults are different of those in child, and also nonspecific. Although these tumors are uncommon in adults, they must be considered in the differential diagnosis of cerebellar masses in the posterior fossa of this age group.

  3. Cine club

    CERN Multimedia

    Ciné club

    2010-01-01

    Monday 13 December 2010 at 18:30 / Lundi 13 Décembre 2010 à 18:30 CERN Main Auditorium / Amphithéâtre Principal Comme chaque année avant Noël, le CINE-CLUB du CERN est heureux d’inviter petits et grands à une projection gratuite du film.   Ponyo sur la falaise (Japon, 2008, Hayao Miyazaki) Le petit Sosuke vit avec sa mère sur une haute falaise surplombant la mer. Un beau jour, il découvre sur la plage caillouteuse Ponyo, une petite fille poisson. Ponyo est si fascinée par Sosuke et le monde terrestre que son désir le plus cher est de devenir un être humain. Mais Fujimoto, son magicien de père, n’est pas du tout d’accord avec cette idée et il la force à regagner les profondeurs de l’océan. Bien décidée à revoir Sosuke, Ponyo s’&...

  4. Characteristic CT and MRI findings of intracranial chondroma

    Energy Technology Data Exchange (ETDEWEB)

    Duan, Fuhong; Qiu, Shijun; Liu, Zhenyin; Lv, Xiaofei; Feng, Xia; Xiong, Wei; An, Jie; Chen, Jing; Yang, Weicong; Wen, Chuhong [Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong (China)], E-mail: qiushijun006@163.com; Jiang, Jianwei; Chang, Jun [Department of Radiology, The Third Affiliated Hospital of Nantong University, Wuxi, Jiangsu (China)

    2012-12-15

    Background. Intracranial chondromas are rare benign tumors. To date, few data are available on their neuroradiological features. Purpose. To describe a series of patients with intracranial chondroma and to analyze and discuss the computed tomography (CT) and magnetic resonance imaging (MRI) features that may distinguish chondromas from other intracranial neoplasms. Material and Methods. We retrospectively analyzed clinical and medical imaging data of six patients who had pathologically confirmed intracranial chondromas in our two institutions between July 2006 and September 2011. Both CT and MRI scanning were performed in all six cases. Results. Five tumors were located at the skull base and one originated from the falx. CT images revealed well-demarcated, irregular lobulated and variable density masses with obvious calci?cation (6/6), no or slight enhancement, without peritumoral edema, and frequently accompanied by erosion and destruction of surrounding bone (5/6). Tumor parenchyma appeared heterogeneously hypointense on T1WI, and hyperintense or mixed hyperintense and hypointense on T2WI, while the calcification appeared hypointense on T1WI and T2WI in five cases, demonstrating significant inhomogeneous enhancement on postcontrast MRI, which revealed the typical 'punica granatum seeds' sign. Only one case showed homogeneous low signal intensity on T1WI and high signal intensity on T2WI, and relatively uniform obvious enhancement on postcontrast scans. Conclusion. These characteristic CT and MR findings, combined with the location of the lesions and the history of a long duration of clinical symptoms, may prove helpful in differentiating intracranial chondromas from other more common tumors.

  5. Characteristic CT and MRI findings of intracranial chondroma

    International Nuclear Information System (INIS)

    Background. Intracranial chondromas are rare benign tumors. To date, few data are available on their neuroradiological features. Purpose. To describe a series of patients with intracranial chondroma and to analyze and discuss the computed tomography (CT) and magnetic resonance imaging (MRI) features that may distinguish chondromas from other intracranial neoplasms. Material and Methods. We retrospectively analyzed clinical and medical imaging data of six patients who had pathologically confirmed intracranial chondromas in our two institutions between July 2006 and September 2011. Both CT and MRI scanning were performed in all six cases. Results. Five tumors were located at the skull base and one originated from the falx. CT images revealed well-demarcated, irregular lobulated and variable density masses with obvious calci?cation (6/6), no or slight enhancement, without peritumoral edema, and frequently accompanied by erosion and destruction of surrounding bone (5/6). Tumor parenchyma appeared heterogeneously hypointense on T1WI, and hyperintense or mixed hyperintense and hypointense on T2WI, while the calcification appeared hypointense on T1WI and T2WI in five cases, demonstrating significant inhomogeneous enhancement on postcontrast MRI, which revealed the typical 'punica granatum seeds' sign. Only one case showed homogeneous low signal intensity on T1WI and high signal intensity on T2WI, and relatively uniform obvious enhancement on postcontrast scans. Conclusion. These characteristic CT and MR findings, combined with the location of the lesions and the history of a long duration of clinical symptoms, may prove helpful in differentiating intracranial chondromas from other more common tumors

  6. Rare case of acute dengue encephalitis with correlated MRI findings

    International Nuclear Information System (INIS)

    Dengue encephalitis is extremely rare, with most patients showing no significant abnormality on neuroimaging (CT/MRI). We report one of the very few documented cases of dengue encephalitis, with abnormal signal intensities on all major sequences on brain MRI.

  7. Adhesive capsulitis: contrast-enhansed shoulder MRI findings

    International Nuclear Information System (INIS)

    Full text: Evaluation of contrast-enhanced magnetic resonance imaging (CE-MRI) findings in cases clinically diagnosed as adhesive capsulitis (AC). CE-MRI images of 12 cases diagnosed as AC (13 shoulder joints) and nine control cases were retrospectively evaluated. AC diagnosis was establlished based on the history and clinical symptoms. MR signal intensity changes in the axillary pouch, rotator interval, biceps anchor and anterior posterior capsules were analysed with regard to the presence of abnormal soft tissue and contrast enhancement. Capsular and synovial thickening were measured in the axillary recess and rotator interval on coronal oblique CE T1-weighted images. Patient and control groups were compared by Fisher's exact and McNemar tests in terms of signal intensity changes and contrast enhancement in the described areas. Results: Comparison of the group with AC and the control group regarding intensity changes showed a statistically significant difference in the axillary pouch (P 0.05). Comparison of AC and control groups in terms of contrast enhancement revealed statistically significant differences in the axillary pouch, rotator interval, biceps anchor and anterior-posterior capsules (P < 0.001). A significant difference was determined between the AC and control groups with regard to thickening in axillary pouch and rotator interval (P < 0.001). CE studies are useful for diagnosis of AC as it demonstrates thickening of specific soft-tissue areas like joint capsule and synovium.

  8. MRI findings of olivopontocerebellar atrophy and Machado-Joseph disease

    International Nuclear Information System (INIS)

    Olivopontocerebellar atrophy (OPCA) and Machado-Joseph disease (MJD) occasionally show similar clinical signs and symptoms, which makes differential diagnosis of OPCA and MJD difficult. In 1990, Savoiardo et al. reported that the transverse pontine fibers of OPCA patients had high signal intensity on T2-weighted MR images. To determine if the high signal intensity of the transverse pontine fibers is useful for the differential diagnosis of OPCA and MJD, we examined this abnormal intensity in patients diagnosed as OPCA or MJD. We observed the high intensity of transverse pontine fibers in all of the 18 OPCA patients. This finding, however, was not observed in any of the patients with the MJD. The high signal intensity of the transverse pontine fibers in T2-weighted images is characteristic of OPCA patients. Furthermore, the atrophy of pontine tegmentum is characteristic of patients with MJD. These findings correlate well with pathological findings of OPCA and MJD, indicating the usefulness of these MRI findings for the differential diagnosis of OPCA and MJD. (author)

  9. An isolated fourth ventricle in neurosarcoidosis: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Hesselmann, Volker; Terstegge, Klaus; Schulte, Oliver; Krug, Barbara; Lackner, Klaus [Department of Radiology, University of Cologne, Joseph Stelzmann Strasse 9, 50924 Cologne (Germany); Wedekind, Christoph [Department of Neurosurgery, University of Cologne, Joseph Stelzmann Strasse 9, 50924 Cologne (Germany); Voges, Juergen [Department of Stereotaxy und Functional Neurosurgery, University of Cologne, Joseph Stelzmann Strasse 9, 50924 Cologne (Germany)

    2002-07-01

    We report on an isolated enlargement of the fourth ventricle in a patient with neurosarcoidosis which developed 3 years after the insertion of a ventriculo-atrial shunt. Repeated MRI images were obtained in a patient with known neurosarcoidosis between 1995 and 2000. Imaging findings were correlated to the medical course of the patient, who developed a hydrocephalus and a trapped fourth ventricle consecutively. The isolation was presumably due to granulomatous inflammation of the ependyma surrounding the fourth ventricular outlets. The isolated fourth ventricle was responsible for a deterioration of neurological status. Neurosarcoidosis is a severe complication in sarcoidosis patients. An isolated enlargement of the fourth ventricle is a rare complication in clinically deteriorated patients with neurosarcoidosis and ventricular drainage, which may require neurosurgical treatment. (orig.)

  10. MRI findings of muscle involvement in idiopathic hypereosinophilic syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Hundt, W.; Staebler, A.; Reiser, M. [Department of Diagnostic Radiology, Klinikum Grosshadern, Muenchen (Germany)

    1999-04-01

    A 40-year-old white man presented with fever, muscle pain, skin nodules and persistent hypereosinophilia over a period of 1 year. In addition, he had ventricular arrhythmias with episodes of tachycardia. Besides a lack of response to antiparasitic therapy, laboratory and pathological data excluded the diagnosis of trichinosis or any other parasitic infection. The patient`s course of the disease over the previous 1{sup 1}/{sub 2} years was compatible with hypereosinophilic syndrome. In a muscle biopsy several eosinophilic perivascular and leucocytic intravascular infiltrates were found, indicative of muscle involvement by the disease. This is a report on the MRI findings of muscle involvement in idiopathic hypereosinophilic syndrome. (orig.) With 3 figs., 25 refs.

  11. Bilateral Renal Lymphangiomatosis: Ultrasound, CT, and MRI Findings

    Directory of Open Access Journals (Sweden)

    M. H. Bagheri

    2008-01-01

    Full Text Available Background/Objective: Renal lymphangiomatosis (RL is a rare disorder characterized by developmental malformation of the lymphatic system surrounding the kidneys. Herein we describe the ultrasound, CT scan, and MRI features of renal lymphangiomatosis in an asymptomatic male patient."nCase Presentation: A 21 years-old man underwent abdominal ultrasound due to 1 month history of dyspepsia and epigastric pain which revealed mild enlargement of both kidneys (right: accompanied by increased renal echogenicity and loss of corticomedullary differentiation . There were also numerous cystic areas of varying size around both kidneys and also extending along the renal hilum into the peripelvic area obliterating renal sinus fat. All were simple cysts without internal echogenicic debris. Subsequently abdominal CT scan was requested in this patient to better evaluation of the extent and nature of the pathology, which revealed bilateral multilocular fluid-filled cystic masses with thin walls in the perirenal and peripelvic region with attenuation measurement of 8 HU. There was a small focus of calcification posterior to the right kidney. MRI of the patient revealed bilaterally enlarged kidneys with multiple hyperintense lesions in both perirenal spaces and the peripelvic area in T2-wieghted images. These cystic spaces appeared hypointense in T1-weighted images with no enhancement in post-contrast images."nDiscussion: The diagnosis of renal lymphangiomatosis can be confirmed with needle aspiration of the typi-cal chylous content of the pernephric collection; however the imaging findings are actually character-istics for this disease and allow a purely radiologic diagnosis to be made confidently; so familiarity with imaging findings of renal lymphangiomatosis is very useful for radiologists and can prevent unnecessary biopsy or even surgery of this most commonly harm-less condition."nThere is no treatment in most cases of this disease as most patients are asymptomatic. Percutaneous drainage has promised useful in conservative manage-ment of symptomatic patients and pregnant women.     

  12. MRI findings of multiple sclerosis involving the brainstem

    International Nuclear Information System (INIS)

    To describe MRI findings of multiple sclerosis involving the brainstem. Among 35 cases of clinically definite multiple sclerosis, the authors retrospectively analysed 20 in which the brainstem was involved. MR images were analysed with regard to involvement sites in the brainstem or other locations, signal intensity, multiplicity, shape, enhancement pattern, and contiguity of brainstem lesions with cisternal or ventricular CSF space. The brainstem was the only site of involvement in five cases (25%), while simultaneous involvement of the brainstem and other sites was observed in 15 cases (75%). No case involved only the midbrain or medulla oblongata, and simultaneous involvement of the midbrain, pons and medulla oblongata was noted in 12 cases (60%). The most frequently involved region of the brainstem was the medulla oblongata (n=13; 90%), followed by the pons (n=17; 85%) and the midbrain (n=16; 80%). Compared with normal white matter, brainstem lesions showed low signal intensity on T1 weighted images, and high signal intensity on T2 weighted, proton density weighted, and FLAIR images. In 17 cases (85%), multiple intensity was observed, and the shape of lesions varied: oval, round, elliptical, patchy, crescentic, confluent or amorphous were seen on axial MR images, and in 14 cases (82%), coronal or sagittal scanning showed that lesions were long and tubular. Contiguity between brainstem lesions and cisternal or ventricular CSF space was seen in all cases (100%) involving midbrain (16/16) and medulla oblongata (18/18) and in 15 of 17 (88%) involving the pons. Contrast enhancement was apparent in 7 of 12 cases (58%). In the brainstem, MRI demonstrated partial or total contiguity between lesions and cisternal or ventricular CSF space, and coronal or sagittal images showed that lesions were long and tubuler

  13. Intratemporal and extratemporal facial nerve schwannoma: CT and MRI findings

    International Nuclear Information System (INIS)

    To analyze the characteristics of CT and MRI findings of facial nerve schwannoma in ten patients. Ten patients with pathologically confirmed facial nerve schwannoma, underwent physical and radilolgic examination. The latter involved MRI in all ten and CT scanning in six. We analyzed the location (epicenter), extent and number of involved segments of tumors, tuumor morphology, and changes in adjacent bony structures. The major symptoms of facial nerve schwannoma were facial nerve paralysis in seven cases and hearing loss in six. Epicenters were detected at the intraparotid portion in five cases, the intracanalicular portion in two, the cisternal portion in one, and the intratemporal portion in two. The segment most frequently involved was the mastoid (n=6), followed by the parotid (n=5), intracanalicular (n=4), cisternal (n=2), the labyrinthine/geniculate ganglion (n=2) and the tympanic segment (n=1). Tumors affected two segments of the facial nerve in eight cases, only one segment in one, and four continuous segments in one. Morphologically, tumors were ice-cream cone shaped in the cisternal segment tumor (1/1), cone shaped in intracanalicular tumors (2/2), oval shaped in geniculate ganglion tumors (1/1), club shaped in intraparotid tumors (5/5) and bead shaped in the diffuse-type tumor (1/1). Changes in adjacent bony structures involved widening of the stylomastoid foramen in intraparotid tumors (5/5), widening of the internal auditary canal in intracanalicular and cisternal tumors (3/3), bony erosion of the geniculate fossa in geniculate ganglion tumors (2/2), and widening of the facial nerve canal in intratemporal and intraparotid tumors (6/6). The characteristic location, shape and change in adjacent bony structures revealed by facial schwannomas on CT and MR examination lead to correct diagnosis

  14. First metatarsophalangeal joint- MRI findings in asymptomatic volunteers

    International Nuclear Information System (INIS)

    To evaluate the spectrum and frequency of MR findings of the first metatarsophalangeal joint (MTPJ) in asymptomatic volunteers. MR imaging of 30 asymptomatic forefeet was performed with a dedicated extremity 1.5-Tesla system. Participants were between 20 and 49 years of age (mean ± SD: 35.5 ± 8.4 years). Two radiologists assessed cartilage, bone, capsuloligamentous structures, and tendons of first MTPJs on MR images. Cartilage defects were observed in 27 % (n = 8) of first MTPJs, most frequently located at the base of the proximal phalanx (23 %, n = 7), whereas cartilage defects of the metatarsal head (13 %, n = 4) and the metatarsosesamoid compartment were rare (0 %-3 %, n = 0-1). Bone marrow oedema-like signal changes were present in 37 % (n = 11) and subchondral cysts in 20 % (n = 6) of first MTPJs. Hyperintense areas on intermediate-weighted sequences (range: 30-43 %, n = 9-13) and on fluid-sensitive sequences with fat suppression (range: 33-60 %, n = 10-18) within the medial and lateral collateral ligament complex were common. Plantar recesses (77 %, n = 23) and distal dorsal recesses (87 %, n = 26) were frequently observed. Cartilage defects, bone marrow oedema-like signal changes, subchondral cysts, plantar recesses, and distal dorsal recesses were common findings on MRI of first MTPJs in asymptomatic volunteers. The collateral ligaments were often heterogeneous in structure and showed increased signal intensity. (orig.)

  15. First metatarsophalangeal joint- MRI findings in asymptomatic volunteers

    Energy Technology Data Exchange (ETDEWEB)

    Dietrich, Tobias Johannes; Pfirrmann, Christian W.A. [University of Zurich, Radiology, Orthopedic University Hospital Balgrist, Zurich (Switzerland); Figueira da Silva, Flora Luciana [University of Zurich, Radiology, Orthopedic University Hospital Balgrist, Zurich (Switzerland); Radiology, Hospital Mae de Deus and Mae de Deus Center, Porto Alegre, RS (Brazil); Abreu, Marcelo Rodrigues de [Radiology, Hospital Mae de Deus and Mae de Deus Center, Porto Alegre, RS (Brazil); Klammer, Georg [University of Zurich, Orthopedic Surgery, Orthopedic University Hospital Balgrist, Zurich (Switzerland)

    2015-04-01

    To evaluate the spectrum and frequency of MR findings of the first metatarsophalangeal joint (MTPJ) in asymptomatic volunteers. MR imaging of 30 asymptomatic forefeet was performed with a dedicated extremity 1.5-Tesla system. Participants were between 20 and 49 years of age (mean ± SD: 35.5 ± 8.4 years). Two radiologists assessed cartilage, bone, capsuloligamentous structures, and tendons of first MTPJs on MR images. Cartilage defects were observed in 27 % (n = 8) of first MTPJs, most frequently located at the base of the proximal phalanx (23 %, n = 7), whereas cartilage defects of the metatarsal head (13 %, n = 4) and the metatarsosesamoid compartment were rare (0 %-3 %, n = 0-1). Bone marrow oedema-like signal changes were present in 37 % (n = 11) and subchondral cysts in 20 % (n = 6) of first MTPJs. Hyperintense areas on intermediate-weighted sequences (range: 30-43 %, n = 9-13) and on fluid-sensitive sequences with fat suppression (range: 33-60 %, n = 10-18) within the medial and lateral collateral ligament complex were common. Plantar recesses (77 %, n = 23) and distal dorsal recesses (87 %, n = 26) were frequently observed. Cartilage defects, bone marrow oedema-like signal changes, subchondral cysts, plantar recesses, and distal dorsal recesses were common findings on MRI of first MTPJs in asymptomatic volunteers. The collateral ligaments were often heterogeneous in structure and showed increased signal intensity. (orig.)

  16. Cardiac MRI: evaluation of phonocardiogram-gated cine imaging for the assessment of global und regional left ventricular function in clinical routine

    International Nuclear Information System (INIS)

    To validate a phonocardiogram (PCG)-gated cine imaging approach for the assessment of left ventricular (LV) function. In this prospective study, cine MR imaging of the LV was performed twice in 79 patients by using retrospectively PCG- and retrospectively ECG-gated cine SSFP sequences at 1.5 T. End-diastolic volumes (EDV), end-systolic volumes (ESV), stroke volumes (SV), ejection fraction (EF), muscle mass (MM), as well as regional wall motion were assessed. Subgroup analyses were performed for patients with valvular defects and for patients with dysrhythmia. PCG-gated imaging was feasible in 75 (95%) patients, ECG-gating in all patients. Excellent correlations were observed for all volumetric parameters (r > 0.98 for all variables analysed). No significant differences were observed for EDV (-0.24 ± 3.14 mL, P = 0.5133), ESV (-0.04 ± 2.36 mL, P = 0.8951), SV (-0.20 ± 3.41 mL, P = 0.6083), EF (-0.16 ± 1.98%, P = 0.4910), or MM (0.31 ± 4.2 g, P = 0.7067) for the entire study cohort, nor for either of the subgroups. PCG- and ECG-gated cine imaging revealed similar results for regional wall motion analyses (115 vs. 119 segments with wall motion abnormalities, P = 0.3652). The present study demonstrates that PCG-gated cine imaging enables accurate assessment of global and regional LV function in the vast majority of patients in clinical routine. (orig.)

  17. MRI reporting by radiographers: Findings of an accredited postgraduate programme

    Energy Technology Data Exchange (ETDEWEB)

    Piper, Keith [Allied Heath Professions Department, Canterbury Christ Church University, North Holmes Road, Canterbury, Kent CT1 1QU (United Kingdom)], E-mail: keith.piper@canterbury.ac.uk; Buscall, Kaie [Allied Heath Professions Department, Canterbury Christ Church University, North Holmes Road, Canterbury, Kent CT1 1QU (United Kingdom); Thomas, Nigel [X-Ray Department, Trafford General Hospital, Manchester M41 5SL (United Kingdom)

    2010-05-15

    Aim: To analyse the objective structured examination (OSE) results of the first three cohorts of radiographers (n = 39) who completed an accredited postgraduate certificate (PgC) programme in reporting of general magnetic resonance imaging (MRI) investigations and to compare the agreement rates with those demonstrated for a small group of consultant radiologists. Method: Forty MRI investigations were used in the OSE which included the following anatomical areas and abnormal appearances: knee; meniscal/ligament injuries, bone bruises, effusions and osteochondral defects; lumbar spine: intervertebral disc morphology, vertebral collapse, tumours (bone and soft tissue), spinal stenosis and/or nerve root involvement; internal auditory meati (IAM): acoustic neuroma. Incidental findings included maxillary polyp, arachnoid cyst, renal cyst, hydroureter, pleural effusion and metastases (adrenal, lung, perirenal and/or thoracic spine). Sensitivity, specificity and total percentage agreement rates were calculated for all radiographers (n = 39) using all reports (n = 1560). A small representative subgroup of reports (n = 27) was compared to the three consultant radiologists' reports which were produced when constructing the OSE. Kappa values were estimated to measure agreement in four groups: consultant radiologists only; radiographers and each of the consultant radiologists independently. Results: The sensitivity, specificity and agreement rates for the three cohorts (combined) of radiographers were 99.0%, 99.0% and 89.2%, respectively. For the majority (5/9) of anatomical areas and/or pathological categories no significant differences (p < 0.05) were found between the mean Kappa scores (K = 0.47-0.76) for different groups of observers, whether radiographers were included in the group analysis or not. Where differences were apparent, this was in cases (4/9) where the variation was either not greater than found between radiologists and/or of no clinical significance. These results suggest therefore that in an academic setting, these groups of radiographers have the ability to correctly identify normal investigations and are able to provide a report on the abnormal appearances to a high standard. Further work is required to confirm the clinical application of these findings.

  18. MRI findings of brain damage due to neonatal hypoglycemia

    International Nuclear Information System (INIS)

    Objective: To report the MRI findings of brain damage observed in neonatal patients who suffered from isolated hypoglycemia and to explore the value of diffusion-weighted imaging(DWI) in early detection of neonatal hypoglycemic brain injury. Methods: Twelve neonates with isolated hypoglycemia (10 of the 12 were diagnosed to suffer from hypoglycemic encephalopathy) were enrolled in this study. They were first scanned at age from 3 days to 10 days with T1WI, T2WI and DWI(b is 0 s/mm2, 1000 s/mm2), and 4 of them were then scanned from 7 days to 10 days following the initial scan. All acquired MR images were retrospectively analysed. Results: First series of DWI images showed distinct hyperintense signal in 11 cases in several areas including bilateral occipital cortex (2 cases), right occipital cortex (1 case), left occipital cortex and subcortical white matter(1 case), bilateral occipital cortex and subcortical white matter (2 cases), bilateral parieto-occipital cortex (2 cases), bilateral parieto-occipital cortex and subcortical white matter(2 cases), the splenium of corpus callosum (4 cases), bilateral corona radiata( 2 cases), left caudate nucleus and globus pallidus (1 case), bilateral thalamus (1 case), bilaterally posterior limb of internal capsule (1 case). In the initial T1WI and T2WI images, there were subtle hypointensity in the damaged cortical areas (3 cases), hyperintensity in the bilaterally affected occipital cortex( 1 case) on T1 weighted images, and hyperintensity in the affected cortex and subcortical white matter with poor differentiation on T2 weighted images. The followed-up MRI of 4 cases showed regional encephalomalacia in the affected occipital lobes(4 cases), slightly hyperintensity on T2 weighted images in the damaged occipital cortex (2 cases), extensive demyelination (1 case), disappearance of hyperintensity of the splenium of corpus callosum (1 case), and persistent hyperintensity in the splenium of corpus callosum (1 case) on T2 weighted images. Conclusion: The findings suggest that posterior parieto-occipital regions are most frequently injured in neonatal period due to severe hypoglycemia. DWI is a useful technique in the early detection and evaluation of hypoglycemic brain injury of neonates. (authors)

  19. MRI reporting by radiographers: Findings of an accredited postgraduate programme

    International Nuclear Information System (INIS)

    Aim: To analyse the objective structured examination (OSE) results of the first three cohorts of radiographers (n = 39) who completed an accredited postgraduate certificate (PgC) programme in reporting of general magnetic resonance imaging (MRI) investigations and to compare the agreement rates with those demonstrated for a small group of consultant radiologists. Method: Forty MRI investigations were used in the OSE which included the following anatomical areas and abnormal appearances: knee; meniscal/ligament injuries, bone bruises, effusions and osteochondral defects; lumbar spine: intervertebral disc morphology, vertebral collapse, tumours (bone and soft tissue), spinal stenosis and/or nerve root involvement; internal auditory meati (IAM): acoustic neuroma. Incidental findings included maxillary polyp, arachnoid cyst, renal cyst, hydroureter, pleural effusion and metastases (adrenal, lung, perirenal and/or thoracic spine). Sensitivity, specificity and total percentage agreement rates were calculated for all radiographers (n = 39) using all reports (n = 1560). A small representative subgroup of reports (n = 27) was compared to the three consultant radiologists' reports which were produced when constructing the OSE. Kappa values were estimated to measure agreement in four groups: consultant radiologists only; radiographers and each of the consultant radiologists independently. Results: The sensitivity, specificity and agreement rates for the three cohorts (combined) of radiographers were 99.0%, 99.0% and 89.2%, respectively. For the majority (5/9) of anatomical areas and/or pathological categories no significant differences (p < 0.05) were found between the mean Kappa scores (K = 0.47-0.76) for different groups of observers, whether radiographers were included in the group analysis or not. Where differences were apparent, this was in cases (4/9) where the variation was either not greater than found between radiologists and/or of no clinical significance. These results suggest therefore that in an academic setting, these groups of radiographers have the ability to correctly identify normal investigations and are able to provide a report on the abnormal appearances to a high standard. Further work is required to confirm the clinical application of these findings.

  20. Left-ventricular reduction surgery: pre- and postoperative evaluation by cine magnetic resonance imaging; Linksventrikulaere Volumenreduktion: prae- und postoperative Evaluierung mit der Cine MRT

    Energy Technology Data Exchange (ETDEWEB)

    Kivelitz, D.E.; Enzweiler, C.N.H.; Wiese, T.H.; Lembcke, A.; Hamm, B. [Humboldt-Univ., Berlin (Germany). Inst. fuer Radiologie; Hotz, H.; Konertz, W. [Humboldt-Univ., Berlin (Germany). Klinik fuer Kardiovaskulaere Chirurgie; Borges, A.C.; Baumann, G. [Humboldt-Univ., Berlin (Germany). Klinik und Poliklinik fuer Innere Medizin

    2001-04-01

    Aim: To evaluate the role of cine magnetic resonance imaging (MRI) in the preoperative assessment and postoperative follow-up of patients undergoing left ventricular (LV) reduction surgery. Patients and Methods: 6 patients with cardiomegaly were examined on a 1.5 T MR imager before and after LV reduction surgery. The heart was imaged along the short and long axes using a breath-hold ECG-triggered cine gradient-echo sequence for assessing ventricular and valvular morphology and function and performing volumetry (end-diastolic and end-systolic volumes, ejection fraction). Results: Postoperatively, the mean ejection fraction increased from 21.7% to 33.4% and the enddiastolic and end-systolic left ventricular volumes decreased in all patients (304.0 and 252.5 ml before to 205.0 and 141.9 ml after surgery). Mean myocardial mass decreased slightly from 283.8 g to 242.7 g. Differences were significant for all parameters (p<0.05). MRI allowed for the reliable assessment of postoperative valve morphology and yielded additional findings such as the presence of mitral valve insufficiency or ventricular thrombus. Conclusions: Cine MRI provides relevant information prior to left ventricular reduction surgery and reliably depicts functional and morphological changes in the early postoperative follow-up. (orig.) [German] Ziel: Evaluierung der Wertigkeit der Cine MRT in der praeoperativen Diagnostik und im postoperativen Verlauf nach linksventrikulaerer Volumenreduktion. Patienten und Methoden: 6 Patienten mit Kardiomegalie wurden vor und nach ventrikelverkleinernder Operation an einem 1,5 T MRT untersucht. Zur Beurteilung der Ventrikel- und Klappenmorphologie und Funktion und zur Volumetrie (enddiastolisches und -systolisches Volumen, Ejektionsfraktion) wurde das Herz in der kurzen und den langen Achsen mit einer EKG-getriggerten, atemangehaltenen Cine-Gradienten-Echo-Sequenz untersucht. Ergebnisse: Die mittlere Ejektionsfraktion nahm von 21,7% auf 33,4% postoperativ zu. Das enddiastolische und endsystolische linksventrikulaere Volumen verringerte sich postoperativ bei allen Patienten (304,0 bzw. 252,5 ml praeoperativ auf 205,0 bzw. 141,9 ml postoperativ). Die mittlere myokardiale Masse zeigte eine geringe Abnahme von 283,8 g auf 242,7 g. Die Veraenderungen aller ermittelten Parameter waren signifikant (p<0,05). Zusaetzliche Befunde wie das Vorhandensein einer Mitralklappeninsuffizienz, die postoperative Klappenmorphologie sowie das Vorhandensein eines Ventrikelthrombus konnten zuverlaessig erhoben werden. Schlussfolgerungen: Die Cine MRT ist ein geeignetes Verfahren, dem Chirurgen relevante Befunde vor ventrikelverkleinernder Operation zu liefern. In der fruehen postoperativen Verlaufsbeurteilung kann sie funktionelle und morphologische Veraenderungen zuverlaessig darstellen. (orig.)

  1. Dobutamine cine magnetic resonance imaging after myocardial infarction

    International Nuclear Information System (INIS)

    Dobutamine Cine MRI is a new diagnostic imaging technique in the pretreatment (revascularization) assessment of myocardial infarction patients. In this issue are reported the result of a comparative study of the diagnostic yield of dobutamine Cine MRI with that of stress echocardiography in the assessment of viable myocardium. A new method for analysis of Cine MR images, employing digital subtraction, aimed at decreasing subjectivity in the quantitative assessment of myocardial wall thickening. Twenty-six patients (21 men and 5 women) with a history of myocardial infarction who were scheduled for revascularization were submitted to stress echocardiography and dobutamine Cine MRI to evaluate contractile recovery of the segments considered akinetic or hypo kinetic at baseline echocardiography. Dobutamine was administered in growing doses (5, 10, 15?/kg/min). 16 segments of the left ventricle in each patient were considered. In the 416 segments studied, it was found that 307 normo kinetic, 64 scarred and 45 viable segments with stress echocardiography, versus 302 normo kinetic, 83 scarred and 31 viable segments with dobutamine MRI. Three months after revascularization 15 patients were examined to check contractile recovery of the segments considered as viable. Echocardiography had 79% sensitivity and 97% specificity, while Cine MRI had 96% and 86%, respectively. In patients with anteroseptal wall myocardial infarction stress echocardiography had 75% sensitivity and 97% specificity. Echocardiography permits to distinguish viable myocardium and scarred myocardial tissue with good sensitivity and specificity, but Cine MRI performs better. Cine MRI has much higher sensitivity than stress echocardiography and thus makes the technique of choice to evaluate viable myocardium in these sites. The digital subtraction technique is as accurate as manual measurements, but reduces the error rate and permits quicker evaluation, particularly in subendocardial thickening

  2. Cowper's syringocele: diagnosis based on MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Kickuth, Ralph; Laufer, Ulf; Kirchner, Tilmann Heinrich; Herbe, Eva; Kirchner, Johannes [Department of Radiology, Marienhospital Herne, University of Bochum, Herne (Germany); Pannek, Juergen [Department of Urology, Marienhospital Herne, University of Bochum, Herne (Germany)

    2002-01-01

    An 8-year-old boy presenting with intermittent haematuria and dysuria was investigated with voiding cystourethrography (VCUG), urethroscopy and perineal MRI. VCUG and urethroscopy did not provide a definitive diagnosis, while MRI clearly demonstrated a homogeneous, oval cystic lesion extending from the bulbourethral glands and slightly impressing the bulbous urethra. The patient was found to have an imperforate Cowper's syringocele. Treatment consisted of marsupialisation and the patient became symptom free. To the authors' knowledge, this is the first description of the MRI characteristics of an imperforate Cowper's syringocele in a paediatric patient. (orig.)

  3. MRI findings in little leaguer's shoulder

    Energy Technology Data Exchange (ETDEWEB)

    Song, James C.; Lazarus, Martin L. [Northwestern University and Evanston Northwestern Healthcare, Department of Radiology, Evanston, IL (United States); Song, Alexandra Pae [Health Department, Evanston, IL (United States)

    2006-02-15

    Little leaguer's shoulder, a stress injury of the proximal humeral physis, should be considered in the differential diagnosis for an adolescent baseball player with shoulder pain, especially if the player is pitching regularly in a competitive environment. While roentgenographs may or may not be helpful, depending on the duration and severity of the injury, we report the MRI appearance of a case of little leaguer's shoulder. We found MRI helpful in diagnosing injury to the growth plate that was radiographically occult; furthermore, we were able to document the patient's progress with a follow-up MRI examination, which showed improvement with treatment. (orig.)

  4. Malignant brachial plexopathy: A pictorial essay of MRI findings

    Directory of Open Access Journals (Sweden)

    Iyer Veena

    2010-01-01

    Full Text Available For imaging, the brachial plexus is a technically and anatomically challenging region of the peripheral nervous system. MRI has a central role in the identification and accurate characterization of malignant lesions arising here, as also in defining their extent and the status of the adjacent structures. The purpose of this pictorial essay is to describe the MRI features of primary and secondary malignant brachial plexopathies and radiation-induced brachial nerve damage.

  5. Digital cine-imaging

    International Nuclear Information System (INIS)

    Digitization of fluoroscopic images has been developed for the digital cine imaging system as a result of the computer technology, television technology, and popularization of interventional radiology. Present digital cine imaging system is able to offer images similar to cine film because of the higher operatability and better image quality with the development of interventional radiology. As a result, its higher usefulness for catheter diagnosis examination except for interventional radiology was reported, and the possibility of having filmless cine is close to becoming a reality. However several problems have been pointed out, such as spatial resolution, time resolution, storage and exchangeability of data, disconsolidated viewing functions, etc. Anyhow, digital cine imaging system has some unresolved points and lots the needs to be discussed. The tendency of digitization is the passage of the time and we have to promote a study for more useful digital cine imaging system in team medical treatment which centers on the patients. (author)

  6. Functional MRI of the pelvic floor. Method and references values

    International Nuclear Information System (INIS)

    Purpose. Functional cine MRI of the pelvic floor is a yet another modality in addition to various radiological fluoroscopic techniques. This article describes our own method in view of the recent literatur and provides morphometric reference values. Material and method. We examined 20 nulliparous women (range of age: 25-51 years) with normal findings in the gynecological and urodynamic examination. Functional cine MRI was performed on a 1.5 Tesla equipment after opacification of the vagina and rectum. We used a T2-weighted gradient-echo sequence (True-FISP) to determine the position of the reference organs at rest and during straining/defecation. Two different reference lines were used. In addition 29 morphometric and functional parameters were measured, all of them being observer independent. Results. Functional cine MRI was able to show the extent and interaction of the pelvic floor organs in all cases with the reference organs always remaining above the pubococcygeal reference line. The depth of the rectocele was 2 cm. With the exception of the diameter of urogenital hiatus the different parts of the levator ani muscle could not be determined. Discussion. Functional cine MRI using an appropiate organ opacification and slice positioning is an objective, unifying diagnostic approach of the pelvic floor. The reference data given can be of help to distinguish normal from abnormal findings. (orig.)

  7. Neurotuberculosis: Hallazgos intracraneanos en RM Neurotuberculosis: Intracranial MRI findings

    Directory of Open Access Journals (Sweden)

    Jorge Docampo

    2012-06-01

    Full Text Available Objetivos. Mostrar nuestra casuística de pacientes con diagnóstico de tuberculosis intracraneana y describir los diferentes tipos de lesiones documentadas en Resonancia Magnética (RM que caracterizan a esta entidad. Materiales y Métodos. Para el presente trabajo fueron seleccionados, de forma retrospectiva, 20 pacientes con hallazgos positivos de tuberculosis intracraneana. Doce eran de sexo masculino y 8 de sexo femenino, con un rango etario de 8 meses a 49 años de edad (edad media: 21 años. El diagnóstico clínico fue realizado con punción lumbar y cultivo de LCR. Once pacientes presentaron serología positiva para VIH. Las RM fueron realizadas en resonadores de 0.5T y 1.5T, complementadas en dos casos con Tomografía Computada (TC de cerebro. A dos pacientes se les realizó difusión (DWI y a un paciente espectroscopía. Resultados. Del total de pacientes (n=20, 14 presentaron compromiso subaracnoideo en la convexidad y 13 compromiso subaracnoideo cisternal basal (afectación leptomeníngea. En 13 se observaron tuberculomas y 11 presentaron angeítis de grandes vasos; mientras que 7 tuvieron angeítis de pequeños vasos, 7 hidrocefalia, 6 infartos parenquimatosos y 1 afectación paquimeníngea. Quince pacientes tenían lesiones combinadas. Conclusión. La localización más frecuente de neurotuberculosis en esta serie fue meníngea con compromiso leptomeníngeo (14 pacientes con afectación subaracnoidea, seguido de afectación cisternal en 13 pacientes y sólo en un caso fue paquimeníngea. La manifestación parenquimatosa más frecuente fue el tuberculoma (granulomas tuberculosos con 13 casos. De estos, 5 presentaron un patrón miliar y sólo uno comportamiento pseudotumoral.Purposes. To report our case series of patients with a diagnosis of intracranial tuberculosis and to describe the different types of lesions characterizing this entity on Magnetic Resonance Imaging (MRI. Materials and Methods. For the present study, we retrospectively selected 20 patients with positive MRI findings of intracranial tuberculosis. Twelve of them were males and 8 were females, with an age range of between 8 months and 49 years (mean age: 21years. Clinical diagnosis was obtained by lumbar puncture and cerebrospinal fluid (CSF culture. Eleven patients presented positive HIV serology. MRIs were performed using 0.5T and 1.5 T scanners and computed tomography (CT of the brain was also performed in two patients. Diffusion-weighted technique was performed in two patients and spectroscopy in one patient. Results. Of the total patients studied (n=20, 14 presented convexity subarachnoid involvement and 13 subarachnoid basal cystern involvement (leptomeningeal involvement, 13 presented tuberculomas, 11 large-vessel angiitis, 7 smallvessel angiitis, 7 hydrocephalia, 6 parenchymatous infarction and one pachymeningeal involvement. Combined lesions were observed in 15 patients. Conclusion. The most frequent location of neurotuberculosis in this series was meningeal with leptomeningeal involvement (14 patients with subarachnoid involvement, followed by cysternal involvement in 13 patients, and only one patient had pachymeningeal involvement. The most frequent parenchymatous finding of tuberculosis was tuberculoma in 13 patients, 5 with a miliary pattern and only one with pseudo-tumoral behavior.

  8. Neurotuberculosis: Hallazgos intracraneanos en RM / Neurotuberculosis: Intracranial MRI findings

    Scientific Electronic Library Online (English)

    Jorge, Docampo; Carolina, Mariluis; Nadia, González; Carlos, Morales; Claudio, Bruno.

    2012-06-01

    Full Text Available Objetivos. Mostrar nuestra casuística de pacientes con diagnóstico de tuberculosis intracraneana y describir los diferentes tipos de lesiones documentadas en Resonancia Magnética (RM) que caracterizan a esta entidad. Materiales y Métodos. Para el presente trabajo fueron seleccionados, de forma retro [...] spectiva, 20 pacientes con hallazgos positivos de tuberculosis intracraneana. Doce eran de sexo masculino y 8 de sexo femenino, con un rango etario de 8 meses a 49 años de edad (edad media: 21 años). El diagnóstico clínico fue realizado con punción lumbar y cultivo de LCR. Once pacientes presentaron serología positiva para VIH. Las RM fueron realizadas en resonadores de 0.5T y 1.5T, complementadas en dos casos con Tomografía Computada (TC) de cerebro. A dos pacientes se les realizó difusión (DWI) y a un paciente espectroscopía. Resultados. Del total de pacientes (n=20), 14 presentaron compromiso subaracnoideo en la convexidad y 13 compromiso subaracnoideo cisternal basal (afectación leptomeníngea). En 13 se observaron tuberculomas y 11 presentaron angeítis de grandes vasos; mientras que 7 tuvieron angeítis de pequeños vasos, 7 hidrocefalia, 6 infartos parenquimatosos y 1 afectación paquimeníngea. Quince pacientes tenían lesiones combinadas. Conclusión. La localización más frecuente de neurotuberculosis en esta serie fue meníngea con compromiso leptomeníngeo (14 pacientes con afectación subaracnoidea, seguido de afectación cisternal en 13 pacientes) y sólo en un caso fue paquimeníngea. La manifestación parenquimatosa más frecuente fue el tuberculoma (granulomas tuberculosos) con 13 casos. De estos, 5 presentaron un patrón miliar y sólo uno comportamiento pseudotumoral. Abstract in english Purposes. To report our case series of patients with a diagnosis of intracranial tuberculosis and to describe the different types of lesions characterizing this entity on Magnetic Resonance Imaging (MRI). Materials and Methods. For the present study, we retrospectively selected 20 patients with posi [...] tive MRI findings of intracranial tuberculosis. Twelve of them were males and 8 were females, with an age range of between 8 months and 49 years (mean age: 21years). Clinical diagnosis was obtained by lumbar puncture and cerebrospinal fluid (CSF) culture. Eleven patients presented positive HIV serology. MRIs were performed using 0.5T and 1.5 T scanners and computed tomography (CT) of the brain was also performed in two patients. Diffusion-weighted technique was performed in two patients and spectroscopy in one patient. Results. Of the total patients studied (n=20), 14 presented convexity subarachnoid involvement and 13 subarachnoid basal cystern involvement (leptomeningeal involvement), 13 presented tuberculomas, 11 large-vessel angiitis, 7 smallvessel angiitis, 7 hydrocephalia, 6 parenchymatous infarction and one pachymeningeal involvement. Combined lesions were observed in 15 patients. Conclusion. The most frequent location of neurotuberculosis in this series was meningeal with leptomeningeal involvement (14 patients with subarachnoid involvement, followed by cysternal involvement in 13 patients), and only one patient had pachymeningeal involvement. The most frequent parenchymatous finding of tuberculosis was tuberculoma in 13 patients, 5 with a miliary pattern and only one with pseudo-tumoral behavior.

  9. MRI findings of vascular dementia following hypertensive intracerebral hemorrhage

    International Nuclear Information System (INIS)

    This study reviewed 23 patients with vascular dementia following hypertensive intracerebral hemorrhage. There were 12 male and 11 female patients with an age range between 46 and 88 years (median, 62.6 years). They consisted of 9 putaminal, 9 thalamic and 5 recurrent hemorrhages. Vascular dementia was diagnosed by Hasegawa's test for the demented patient. Patients with Hasegawa's score of less than 21.5 were enrolled as dementia. A superconducting magnet MIR system (MRT-50A, 0.5 Tesla) was used. The highest incidence of finding depicted by MRI was cortical atrophy (100%), followed by periventricular high intensity zone (91.3%), periventricular of deep white matter patchy-like high intensity area (73.9%), hydrocephalus and multiple putaminal low intensity spots (52.1%), scattered cortical high intensity area (47.8%) and subdural ring-like high intensity zone (21.7%). Older group of more than 71 years had more frequent multiple putaminal low intensity spots, scattered cortical high intensity area, and relatively frequent hydrocephalus, periventricular high intensity zone, as compared with younger group of less than 69 years. Subdural ring-like high intensity zone was frequently observed in patients with an interval from onset of more than 2 years. Multiple putaminal low intensity spots were frequently seen in patients with less than 1 year's interval. Multiple putaminal low intensity spots and periventricular high intensity zone were more frequently observed in patients with thalamic and recurrent hemorrhages, periventricular or deep white matter patchy-like high intensity areas were seen more frequently in patients with putaminal hemorrhage. Both scattered cortical high intensity area and subdural ring-like high intensity zone were more frequently observed in patients with recurrent hemorrhages. Both hydrocephalus and multiple putaminal low intensity spots were more common in demented patients than predemented patients. (J.P.N.)

  10. Mesenchymal chondrosarcoma of the orbit: CT and MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Yang, B.T., E-mail: cjr.yangbentao@vip.163.com [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing (China); Wang, Y.Z.; Wang, X.Y.; Wang, Z.C. [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing (China)

    2012-04-15

    Aim: To describe the computed tomography (CT) and magnetic resonance imaging (MRI) features of orbital mesenchymal chondrosarcomas (MCSs). Materials and methods: Six patients with histology-confirmed MCSs of the orbit were retrospectively reviewed. All six patients underwent CT and MRI. Imaging studies were evaluated for the following: (a) tumour location, (b) configuration, size, and margin, (c) CT attenuation and MRI signal intensity, and (d) secondary manifestations. Additionally, the time-intensity curve (TIC) of dynamic contrast-enhanced (DCE) MRI were analysed in five patients. Results: Two MCSs arose in the right orbit and four in the left orbit. Five MCSs were located in the retrobulbar intraconal space and one in the extraconal space. All the lesions displayed a lobulate configuration and had a well-defined margin. The mean maximum diameter was 25.8 mm (range 15-36 mm). On unenhanced CT, the lesions appeared isodense to grey matter in six patients, with calcifications in five. Two patients showed inhomogeneous, moderate enhancement on enhanced CT. Six MCSs appeared isointense on T1-weighted imaging and heterogeneously isointense on T2-weighted imaging. The lesions showed significantly heterogeneous contrast enhancement. Five patients had DCE MRI and the TICs showed a rapidly enhancing and rapid washout pattern (type III). The following features were also detected: compression of the extra-ocular muscle (six patients, 100%); displacement of the optic nerve (five patients, 83.3%); and encasing globe (three patients, 50%). Conclusions: A well-defined, lobulate orbital mass with calcification on CT and, marked heterogeneous enhancement and type III TIC on MRI are highly suspicious of orbital MCSs.

  11. MRI findings of the knee in rheumatoid arthritis

    International Nuclear Information System (INIS)

    The studies were done to know in what extent MRI can image the pannus invasion and cysts in the subcartilagious tissues which are not revealed by the scout roentgenogram and how the synovial membrane can be enhanced by gadolinium-DTPA (Gd-DTPA). Twenty five knees in rheumatoid arthritis of 21 patients, mean age of 57.8 years, were subjected to the studies. Thirteen knees were in Larsen grade 0, 3 in grade I, 4 in grade II, 2 in grade III and 3 in grade IV, whose osteolytic degree were small. MRI system was 0.5 Tesla superconducting Toshiba MRT50A. Imaging was performed by the field echo method with 4 mm-thick slice of T1, T2 weighted images of sagittal and frontal sections, and 5 min after intravenous injection of Gd-DTPA, of T1 weighted images of frontal and sagittal sections. Subcartilagious cysts not detectable on the scout roentgenogram were found in 13 knees (52%) on the MRI image. MRI after Gd-DTPA gave the enhanced images of surroundings of joint capsule in 15 cases, of dotted or reticular synovial membrane in 2 and of joint capsule surroundings with dotted membrane in 2. One case showed no enhancement. MRI was thus found useful for detection of cysts and pannus in the early knee rheumatoid arthritis with insignificant osteolysis. MRI after Gd-DTPA enhanced the surroundings of joint capsule in most cases, and in some cases, the synovial membrane in a dotted or reticular manner, which was considered to show the dilated blood vessels or necrotic coagulations of synovial villi. (H.O.)

  12. Tuberous sclerosis: diffusion MRI findings in the brain

    International Nuclear Information System (INIS)

    Diffusion MRI has mainly been used for detection of acute ischemia, and for distinction of cytotoxic and vasogenic edema. We applied diffusion MRI in patients with tuberous sclerosis in order to evaluate diffusion imaging characteristics of parenchymal changes. Five children with known tuberous sclerosis were included in this study. The MRI examinations were performed on a 1.5-T MR unit. Diffusion MRI was obtained using the echo-planar imaging sequence. Apparent diffusion coefficient (ADC) values from the abnormal brain parenchyma were calculated directly from automatically generated ADC maps. Seven normal children were available for comparison. In this control group the mean ADC value of the normal white matter was 0.84±0.12 x 10-3 mm2/s. In tuberous sclerosis patients the mean ADC value of the white matter hamartomas (n=20) was apparently high (1.52±0.24 x 10-3 mm2/s) compared with that of normal white matter. The ADC value of calcified hamartomas was ''zero''. The ADC value within a giant cell tumor was 0.89 x 10-3 mm2/s, similar to that of normal cerebral white matter. The ADC maps were superior to b=1000 s/mm2 (true diffusion) images with respect to lesion evaluation, and they provided mathematical information on tissue integrity. With respect to detection of the exact numbers and sizes of the parenchymal hamartomas fluid-attenuated inversion recovery images were superior to ADC maps. It is believed that diffusion MRI can be useful in evaluation of various parenchymal changes associated with tuberous sclerosis. Further studies on tuberous sclerosis, and on various brain lesions, would provide increasing data on this relatively new MRI sequence. (orig.)

  13. Tuberous sclerosis: diffusion MRI findings in the brain

    Energy Technology Data Exchange (ETDEWEB)

    Sener, R.N. [Department of Radiology, Ege University Hospital, Izmir (Turkey)

    2002-01-01

    Diffusion MRI has mainly been used for detection of acute ischemia, and for distinction of cytotoxic and vasogenic edema. We applied diffusion MRI in patients with tuberous sclerosis in order to evaluate diffusion imaging characteristics of parenchymal changes. Five children with known tuberous sclerosis were included in this study. The MRI examinations were performed on a 1.5-T MR unit. Diffusion MRI was obtained using the echo-planar imaging sequence. Apparent diffusion coefficient (ADC) values from the abnormal brain parenchyma were calculated directly from automatically generated ADC maps. Seven normal children were available for comparison. In this control group the mean ADC value of the normal white matter was 0.84{+-}0.12 x 10{sup -3} mm{sup 2}/s. In tuberous sclerosis patients the mean ADC value of the white matter hamartomas (n=20) was apparently high (1.52{+-}0.24 x 10{sup -3} mm{sup 2}/s) compared with that of normal white matter. The ADC value of calcified hamartomas was ''zero''. The ADC value within a giant cell tumor was 0.89 x 10{sup -3} mm{sup 2}/s, similar to that of normal cerebral white matter. The ADC maps were superior to b=1000 s/mm{sup 2} (true diffusion) images with respect to lesion evaluation, and they provided mathematical information on tissue integrity. With respect to detection of the exact numbers and sizes of the parenchymal hamartomas fluid-attenuated inversion recovery images were superior to ADC maps. It is believed that diffusion MRI can be useful in evaluation of various parenchymal changes associated with tuberous sclerosis. Further studies on tuberous sclerosis, and on various brain lesions, would provide increasing data on this relatively new MRI sequence. (orig.)

  14. CT and MRI of aortic coarctation: pre- and postsurgical findings.

    Science.gov (United States)

    Karaosmanoglu, Ali Devrim; Khawaja, Ranish Deedar Ali; Onur, Mehmet Ruhi; Kalra, Mannudeep K

    2015-03-01

    OBJECTIVE. The purpose of this article is to summarize the roles of CT and MRI in the diagnosis and follow-up of patients with aortic coarctation. CONCLUSION. Aortic coarctation is a common congenital heart disease accounting for approximately 6-8% of congenital heart defects. Despite its deceptively simple anatomic presentation, it is a complex medical problem with several associated anatomic and physiologic abnormalities. CT and MRI may provide very accurate information of the coarctation anatomy and other associated cardiac abnormalities. PMID:25714305

  15. MRI of articular cartilaginous lesions. MRI findings in osteoarthritis of the knee joint

    International Nuclear Information System (INIS)

    An investigation was carried out to assess the usefulness of magnetic resonance imaging for imaging of the knee joint, especially for detecting articular cartilaginous lesions associated with osteoarthritis of the knee. A total of 141 patients with osteoarthritis were examined (23 males, 118 females). Their age range was 40-93 (mean age 66.2). Using radiotherapy examinations, patients were classified according to Hokkaido University Classification Criteria; 22, 49, 46, 16, and 8 patients were classified as Type I, II, III, IV and V, respectively. Articular cartilage defects were examined using MRI, and the number of such defects increased as the X-ray stage progressed. The appearance of a low signal intensity area in the bone marrow was examined using MRI, and the number of patients observed to have such areas increased as the x-ray stages progressed. JOA OA scores were significantly low for patients with meniscal tears. Patients were classified and results reviewed using MRI examinations. Classification by MRI of articular cartilage lesions correlated with the JOA OA scores. Low signal intensity areas in the bone marrow were frequently observed in advanced osteoarthritis cases, and there was correlation between FTA and MRI classifications of these areas. MRI is extremely valuable in detecting articular cartilage lesions in the knee joint, showing those lesions which cannot be detected by conventional radiography examinations. Thus, MRI is judged to be a clinically useful method for diagnosis of osteoarthritis. (author)

  16. Cine-Club

    CERN Multimedia

    CineClub

    2014-01-01

      On the occasion of CERN’s 60th anniversary the CERN CineClub will be showing films from all CERN member states Thursday 10 April 2014 at 20:00 CERN Council Chamber   The Bothersome Man     Directed by Jens Lien (Norway, 2006) 95 minutes   Forty-year-old Andreas arrives in a strange city with no memory of how he got there. He is presented with a job, an apartment-even a beautiful girlfriend. But before long, Andreas notices that something is wrong. The people around him seem cut off from any real emotion, and communicate only in superficialities. All this seems to be governed by a shadowy group of technicians, the ominous Caretakers’, who make sure the city runs smoothly. When they find Andreas is not adjusting to his new life, they keep an increasing watch over his activities...”The Bothersome Man” is a fantastic fable, a parable for modern society’s consumerism and obsession with ap...

  17. Correlation of MRI findings with clinical findings of trochanteric pain syndrome

    International Nuclear Information System (INIS)

    Greater trochanter pain syndrome due to tendinopathy or bursitis is a common cause of hip pain. The previously reported magnetic resonance (MR) findings of trochanteric tendinopathy and bursitis are peritrochanteric fluid and abductor tendon abnormality. We have often noted peritrochanteric high T2 signal in patients without trochanteric symptoms. The purpose of this study was to determine whether the MR findings of peritrochanteric fluid or hip abductor tendon pathology correlate with trochanteric pain. We retrospectively reviewed 131 consecutive MR examinations of the pelvis (256 hips) for T2 peritrochanteric signal and abductor tendon abnormalities without knowledge of the clinical symptoms. Any T2 peritrochanteric abnormality was characterized by size as tiny, small, medium, or large; by morphology as feathery, crescentic, or round; and by location as bursal or intratendinous. The clinical symptoms of hip pain and trochanteric pain were compared to the MR findings on coronal, sagittal, and axial T2 sequences using chi-square or Fisher's exact test with significance assigned as p<0.05. Clinical symptoms of trochanteric pain syndrome were present in only 16 of the 256 hips. All 16 hips with trochanteric pain and 212 (88%) of 240 without trochanteric pain had peritrochanteric abnormalities (p=0.15). Eighty-eight percent of hips with trochanteric symptoms had gluteus tendinopathy while 50% of those without symptoms had such findings (p=0.004). Other than tendinopathy, there was no statistically significant difference between hips with or without trochanteric symptoms and the presence of peritrochanteric T2 abnormality, its size or shape, and the presence of gluteus medius or minimus partial thickness tears. Patients with trochanteric pain syndrome always have peritrochanteric T2 abnormalities and are significantly more likely to have abductor tendinopathy on magnetic resonance imaging (MRI). However, although the absence of peritrochanteric T2 MR abnormalities makes trochanteric pain syndrome unlikely, detection of these abnormalities on MRI is a poor predictor of trochanteric pain syndrome as these findings are present in a high percentage of patients without trochanteric pain. (orig.)

  18. Correlation of MRI findings with clinical findings of trochanteric pain syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Blankenbaker, Donna G.; Ullrick, Steven R.; Davis, Kirkland W.; De Smet, Arthur A. [University of Wisconsin School of Medicine and Public Health, Department of Radiology, Madison, WI (United States); Haaland, Ben; Fine, Jason P. [University of Wisconsin School of Medicine and Public Health, Departments of Biostatistics and Medical Informatics and Statistics, Madison, WI (United States)

    2008-10-15

    Greater trochanter pain syndrome due to tendinopathy or bursitis is a common cause of hip pain. The previously reported magnetic resonance (MR) findings of trochanteric tendinopathy and bursitis are peritrochanteric fluid and abductor tendon abnormality. We have often noted peritrochanteric high T2 signal in patients without trochanteric symptoms. The purpose of this study was to determine whether the MR findings of peritrochanteric fluid or hip abductor tendon pathology correlate with trochanteric pain. We retrospectively reviewed 131 consecutive MR examinations of the pelvis (256 hips) for T2 peritrochanteric signal and abductor tendon abnormalities without knowledge of the clinical symptoms. Any T2 peritrochanteric abnormality was characterized by size as tiny, small, medium, or large; by morphology as feathery, crescentic, or round; and by location as bursal or intratendinous. The clinical symptoms of hip pain and trochanteric pain were compared to the MR findings on coronal, sagittal, and axial T2 sequences using chi-square or Fisher's exact test with significance assigned as p<0.05. Clinical symptoms of trochanteric pain syndrome were present in only 16 of the 256 hips. All 16 hips with trochanteric pain and 212 (88%) of 240 without trochanteric pain had peritrochanteric abnormalities (p=0.15). Eighty-eight percent of hips with trochanteric symptoms had gluteus tendinopathy while 50% of those without symptoms had such findings (p=0.004). Other than tendinopathy, there was no statistically significant difference between hips with or without trochanteric symptoms and the presence of peritrochanteric T2 abnormality, its size or shape, and the presence of gluteus medius or minimus partial thickness tears. Patients with trochanteric pain syndrome always have peritrochanteric T2 abnormalities and are significantly more likely to have abductor tendinopathy on magnetic resonance imaging (MRI). However, although the absence of peritrochanteric T2 MR abnormalities makes trochanteric pain syndrome unlikely, detection of these abnormalities on MRI is a poor predictor of trochanteric pain syndrome as these findings are present in a high percentage of patients without trochanteric pain. (orig.)

  19. MRI findings with periventricular leukomalacia. Correlation with neurological development

    Energy Technology Data Exchange (ETDEWEB)

    Uehara, Hisakazu; Yoshioka, Hiroshi; Hasegawa, Koh; Doi, Yasuo; Matsuo, Yasutaka; Murata, Miyuki; Sawada, Tadashi [Kyoto Prefectural Univ. of Medicine (Japan); Kotani, Hiromi; Goma, Hideyo

    1998-08-01

    In 22 infants with PVL, who were born at 35 weeks gestational age or less, correlation between severity of white matter lesions on MRI and developmental quotient (DQ) of infants was studied. MRI was obtained later than 7 months of age and the severity of white matter lesions was classified as follows: Group I: periventricular white matter is focally affected (n=7), Group II: periventricular white matter is diffusely affected (n=10), and Group III: subcortical white matter is also affected (n=5). Perinatal characteristics including gestational weeks, birth weight, Apgar score, procedure of delivery, and duration of mechanical ventilation revealed no significant differences between the groups. Seventeen infants developed cerebral palsy, while the other 5 infants (4 in Group I, 1 in Group II) showed normal development at 1 year of age, MRI of 4 among these 5 infants only revealed unilateral cysts around the anterior horn of lateral ventricles. Enjoji developmental test showed significant differences in gross motor DQ between Group I and III at both 1 and 2 corrected ages. Although more quantitative criteria will be required for precise classification, it is suggested that the severity of the white matter lesions on MRI is well correlated with gross motor development in PVL. (author)

  20. Comparison of clinical and MRI findings in Chiari malformation

    International Nuclear Information System (INIS)

    Chiari malformation (CM) using magnetic resonance imaging (MRI) which allows to establish its type and to determine the ratio and characteristics of clinical picture of different types of CM was studied. The characteristics of anatomical varieties of CM were determined. Disturbances of liquor dynamics (including intracranial hypertension hydrocephalus) were noted. Combination of CM and syringomyelia and other cerebral and spinal diseases were revealed

  1. MRI findings in the upper cervical spine of rheumatoid arthritis

    Energy Technology Data Exchange (ETDEWEB)

    Kawaida, Hidefumi; Sakou, Takashi; Morizono, Yoshiyuki; Yoshikuni, Nagatoshi; Taketomi, Eiji; Hashiguchi, Masanao

    1989-04-01

    In 55 patients with rheumatoid arthritis associated with upper cervical spine abnormality, the presence or absence of medullary and upper cervical pressures was examined on sagittal MRI scans. Atlanto-dental anterior incomplete dislocation and horizontal dislocation were imaged concurrently with X-rays. For horizontal dislocation, an abnormal Redlund-Johnell value and a Ranawat value of 7 mm or less were always associated with medullary pressure as seen on MRI. For anterior incomplete dislocation, upper cervical pressure was always associated when a space available for the spinal cord was 13 mm or less or frequently associated when the atlanto-dental interval was 8 mm or more. Many of the patients with the upper cervical abnormalities complained of occipital or cervical pain. The pain was always encountered in patients with an abnormal Redlund-Johnell value. Roentgenography of the cervical spine confirmed MRI-proven medullary or upper cervical pressure, suggesting the potential of MRI in the treatment of rheumatoid arthritis. (Namekawa, K).

  2. Transient neonatal hypoglycemia: cranial US and MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Cakmakci, H.; Usal, C.; Karabay, N.; Kovanlikaya, A. [Dept. of Radiology, Dokuz Eyluel Univ., Izmir (Turkey)

    2001-12-01

    A case of transient neonatal hypoglycemia with patchy hyperechogenic white matter abnormalities in the frontal and parietooccipital lobes on cranial US is presented. An MRI examination revealed T1 and T2 shortening of the lesions in the occipital and frontal white matter. Follow-up cranial US demonstrated recovery of white matter changes in the patient with normal neurological outcome. (orig.)

  3. Transient neonatal hypoglycemia: cranial US and MRI findings

    International Nuclear Information System (INIS)

    A case of transient neonatal hypoglycemia with patchy hyperechogenic white matter abnormalities in the frontal and parietooccipital lobes on cranial US is presented. An MRI examination revealed T1 and T2 shortening of the lesions in the occipital and frontal white matter. Follow-up cranial US demonstrated recovery of white matter changes in the patient with normal neurological outcome. (orig.)

  4. Subacute Combined Degeneration: A Case With Spinal MRI Findings Improving Before The Clinical Features

    Directory of Open Access Journals (Sweden)

    Nicer Korkut BICAK

    2007-06-01

    Full Text Available We report a 66-year-old lady with myelopathy due to vitamin B12 deficiency. Spinal MRI revealed coalescent hyperintensities of the dorsal cervical and thoracic spinal cord on T2-weighted images. After three months of vitamin B12 treatment MRI findings disappeared before complete remission of the clinical features.

  5. Comparison of arthoroscopic findings and high-resolution MRI using a microscopy coil findings for triangle fibrocartilage complex injury

    International Nuclear Information System (INIS)

    Triangle fibrocartilage complex (TFCC) is very small and can be visualized in MRI. We compared image findings acquired by high-resolution MRI using a 47-mm-diameter microscopy coil with arthroscopic findings and reviewed the availability and possibility of application of both these techniques. The subjects were 16 patients who underwent arthroscopy of the radiocarpal joint and MRI for the diagnosis of pain in the ulnar wrist joint. Based on image evaluation, the impaired site was categorized as follows radius attachment, disc proper, triangular ligament (upper lamina), triangular ligament (lower lamina), lunate bone cartilage face, and triquete bone cartilage face; the findings of both techniques for impaired site around part 6 were compared. Joint morphology was assessed by the gradient-recalled echo (GRE) method with T2-weighted images, and the cartilage side was analyzed the fast SE (FSE) method with proton density-weighted image. Three orthopedic surgeons and 1 radiologist interpreted the results. The impaired site was verified in all 16 patients by high-resolution MRI using a microscopy coil. The MRI findings were as follows radius attachment in 2 patients, disc proper in 4, upper lamina in 7, lower lamina in 5, lunate bone cartilage face in 3, and triquete bone cartilage face in 0. The frequency of injury according to arthroscopic findings was as follows: radius attachment in 2 patients, disc proper in 4, lunate bone cartilage face in 6, and triquete bone cartilage face in 0. The sensibility/specificity of arthroscopic findings in comparison with MRI findings was as follows: radius attachment 100%/100%, disc proper 75%/91.7%, lunate bone cartilage face 50%/100%, and triquete bone cartilage face 0%/100%. Eight of 16 patients had depression of TFCC tone, and the sensibility/specificity of arthroscopic findings in comparison with MRI findings for the depression of site and TFCC tone was as follows: upper lamina 75%/87.5% and lower lamina 50%/87.5%. High-resolution MRI using a microscopy coil was useful for detailed diagnosis of TFCC injury; however, the evaluation of the cartilage face was difficult. The detection of triangular ligament injury by MRI indicated a strong correlation between injury of the upper lamina and the depression of TFCC tone. (author)

  6. MRI findings in the patients with the presumptive clinical diagnosis of Tolosa-Hunt syndrome

    International Nuclear Information System (INIS)

    The aim of this study was to present our experience in MRI diagnosis of 23 patients with the clinical findings suggesting Tolosa-Hunt syndrome (THS). Cranial MRI studies of the patients with a clinical history of at least one episode of unilateral or bilateral orbital and periorbital pain, and associated paresis of one or more of third to sixth cranial nerves, were performed on a 1.5-T MRI scanner. Whereas 5 patients had the diagnosis of THS, paracavernous meningiomas in 4 patients, pituitary macroadenomas with cavernous sinus infiltration in 3 patients, Meckel's cave neurinoma in 1 patient, and suprasellar epidermoid in 1 patient were surgically proven MRI findings. Other pathological MRI findings were leptomeningeal metastases in 3 patients, granulomatous pachymeningitis sequelae in 2 patients, and aneurysm with compression on cavernous sinus in 1 patient. Three patients had normal MRI findings. The incidence of radiologically proven diagnosis of THS among the patients with the clinical findings suggesting THS seemed to be low in our study. In conclusion, MRI is the most valuable imaging technique to distinguish THS from other THS-like entities, and permits a precise assessment, management, and therapeutic planning of the underlying pathological conditions. (orig.)

  7. The MRI findings of a de Garengeot hernia.

    LENUS (Irish Health Repository)

    Halpenny, D

    2012-03-01

    The presence of the appendix within a femoral hernia is rare. It was first described by the French surgeon Jacques Croissant de Garengeot in 1731. This phenomenon accounts for 0.8-1% of all femoral hernias. Acute appendicitis occurring within a femoral hernia is even rarer and is difficult to diagnose pre-operatively. This type of hernia is termed a de Garengeot hernia. The ultrasonographic and CT imaging features of de Garengeot hernias have been described previously. We report a case of a 57-year-old female who presented with a painful right-sided groin mass. She underwent MRI of the inguinal region, which successfully diagnosed this rare hernia pre-operatively. To our knowledge, this is the first description of a de Garengeot hernia diagnosed using MRI.

  8. MRI and CT findings of adult Down's syndrome

    International Nuclear Information System (INIS)

    Cranial CT and MRI were performed in 29 adult patients with Down's syndrome aged from 20 to 46 years to examine early aging. Morphological changes with aging, such as brain atrophy and ventricular enlargement, were generally sparse; however, calculi of the basal nucleus and lesions of deep-seated white matter were significantly increased with aging. The pallidum and putamen were shown as low intensity signals on T2-weighted images in many of patients in their fourties, suggesting their involvement in the occurrence of dyskinesia and parkinsonism symptoms that are likely to occur in the elderly. Localized changes, as shown on CT and MRI, may reflect abnormally early occurrence of aging, which precedes morphological changes such as brain atrophy. (N.K.)

  9. Differential diagnosis of middle ear inflammatory diseases by MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Muneta, Yuki; Yamamoto, Etsuo; Ohmura, Masaki; Mizukami, Chikashi; Oiki, Hiroyuki; Tsuji, Jun; Tanabe, Makito; Funabiki, Kazuo; Saiwai, Shigeo (Kobe City General Hospital (Japan))

    1992-09-01

    Although computed tomography can reveal a soft tissue mass in middle ear diseases as an area of increased density, it cannot differentiate cholesteatoma from other inflammatory tissue. We prospectively studied 30 patients with various middle ear inflammatory diseases, including inflammatory granulation tissue, cholesteatoma and cholesterin granuloma with magnetic resonance imaging (MRI) with or without Gd-DTPA enhancement. Cholesteatoma and inflammatory granulation tissue showed intensity ranging from low to high on T1-weighted images and from high to very high on T2-weighted images. However, cholesteatoma showed either no enhancement or ring enhancement on MR imagings with Gd-DTPA, and it could be differentiated from the Gd-DTPA-enhanced inflammatory granulation tissue. Cholesterin granuloma showed very high intensity on both T1 and T2-weighted images. Therefore, MRI with Gd-DTPA is considered to be useful in the differential diagnosis of these middle ear diseases. (auhtor).

  10. Differential diagnosis of middle ear inflammatory diseases by MRI findings

    International Nuclear Information System (INIS)

    Although computed tomography can reveal a soft tissue mass in middle ear diseases as an area of increased density, it cannot differentiate cholesteatoma from other inflammatory tissue. We prospectively studied 30 patients with various middle ear inflammatory diseases, including inflammatory granulation tissue, cholesteatoma and cholesterin granuloma with magnetic resonance imaging (MRI) with or without Gd-DTPA enhancement. Cholesteatoma and inflammatory granulation tissue showed intensity ranging from low to high on T1-weighted images and from high to very high on T2-weighted images. However, cholesteatoma showed either no enhancement or ring enhancement on MR imagings with Gd-DTPA, and it could be differentiated from the Gd-DTPA-enhanced inflammatory granulation tissue. Cholesterin granuloma showed very high intensity on both T1 and T2-weighted images. Therefore, MRI with Gd-DTPA is considered to be useful in the differential diagnosis of these middle ear diseases. (auhtor)

  11. Typical atypical findings on dynamic MRI of the breast

    International Nuclear Information System (INIS)

    Dynamic contrast enhanced magnetic resonance imaging (DCE MRI) of the breast has become an important tool to detect and characterize breast disease. The American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) provides a standardized vocabulary for describing the morphologic features and contrast kinetics of breast lesions. However, some lesions may show morphologic and dynamic MR features not consistent with their histologic nature resulting in incorrect categorization as malignant or benign. Another cause of diagnostic problems is artifacts. Thus correct interpretation of dynamic MRI of the breast demands knowledge of the most common pitfalls encountered in clinical practice. A pictorial overview of these is presented, with particular reference to the differentiation of malignant tumors from benign lesions.

  12. A case of subacute combined degeneration: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Yamada, K. [Department of Diagnostic Radiology, University of Rochester Medical Center, Rochester, NY (United States)]|[NMR Center, Massachusetts General Hospital, Charlestown, MA (United States); Shrier, D.A.; Tanaka, H.; Numaguchi, Y. [Department of Diagnostic Radiology, University of Rochester Medical Center, Rochester, NY (United States)

    1998-06-01

    The specific spinal cord lesion caused by vitamin B12 deficiency is known as subacute combined degeneration (SCD). Neuropathological studies of SCD show lesions mainly in the posterior and lateral columns, involving the cortico-spinal and spino-cerebellar tracts. We report a case of SCD in a 19-year-old man who presented with 4 weeks history of gradually progressing tingling in both hands. MRI of the cervical spine demonstrated symmetrical areas of T2 signal abnormality involving the dorsal columns of the cervical cord from the C2 through C5 levels associated with spinal cord expansion. He was treated with vitamin B12 supplements and experienced gradual improvement in his clinical symptoms. Repeat MRI of the cervical spine after 2 months revealed slight decrease in the area of abnormal signal. (orig.) With 1 fig., 11 refs.

  13. An atypical case of noninfected iliopsoas bursitis - MRI findings

    OpenAIRE

    Skiadas, Vasilios; Koutoulidis, Vasilios; Plotas, Athanasios

    2009-01-01

    The authors present an unusual case of atypical iliopsoas bursitis in an 81 years-old female patient. The patient asked for medical advice due to a chronic left hip and lower abdominal pain with no specific characteristics. Physical examination revealed a palpable left-sided pelvic mass. Ultrasound examination demonstrated a purely cystic mass that was presumed to be an ovarian cystic malignancy. The patient was referred for an MRI examination, which showed a cystic lesion extending from the ...

  14. Bilateral Renal Lymphangiomatosis: Ultrasound, CT, and MRI Findings

    OpenAIRE

    M. H. Bagheri; Zare, Z; S. Sefidbakht; s. A. Nabavizadeh; J Roozbeh; Salehipour, M.

    2008-01-01

    Background/Objective: Renal lymphangiomatosis (RL) is a rare disorder characterized by developmental malformation of the lymphatic system surrounding the kidneys. Herein we describe the ultrasound, CT scan, and MRI features of renal lymphangiomatosis in an asymptomatic male patient."nCase Presentation: A 21 years-old man underwent abdominal ultrasound due to 1 month history of dyspepsia and epigastric pain which revealed mild enlargement of both kidneys (right: accompanied by increased r...

  15. The Role of Cranial MRI in Identifying Patients Suffering from Child Abuse and Presenting with Unexplained Neurological Findings.

    Science.gov (United States)

    Chabrol, Brigitte; Decarie, Jean-Claude; Fortin, Gilles

    1999-01-01

    A study investigated the usefulness of cerebral magnetic resonance imaging (MRI) in detecting possible child abuse in 12 children with unexplained neurologic findings. MRI findings were diagnostic for physical abuse in eight cases. A diagnosis of child abuse was made in two more cases by a combination of MRI and survey findings. (Author/CR)

  16. MRI and brain spect findings in patients with unilateral temporal lobe epilepsy and normal CT scan

    Directory of Open Access Journals (Sweden)

    P.G. Carrilho

    1994-06-01

    Full Text Available 26 patients with temporal lobe epilepsy clinically documented by several abnormal interictal surface EEGs with typical unitemporal epileptiform activity and a normal CT scan were studied. Interictal99mTC HMPAO brain SPECT and MRI were performed in all subjects. Abnormalities were shown in 61.5% of MRI (n=16 and 65.4% of SPECT (n=17. Hippocampal atrophy associated to a high signal on T2-weighted MRI slices suggesting mesial temporal sclerosis was the main finding (n=12; 75% of abnormal MRI. MRI correlated well to surface EEG in 50% (n=13. There was also a good correlation between MRI and SPECT in 30.7% (n=8. SPECT and EEG were in agreement in 57.7% (n=l5. MRI, SPECT and EEG were congruent in 26.9% (n=7. These results support the usefulness of interictal brain SPECT and MRI in detecting lateralized abnormalities in temporal lobe epilepsy. On the other hand, in two cases, interictal SPECT correlated poorly with surface EEG. This functional method should not be used isolately in the detection of temporal lobe foci. MRI is more useful than CT as a neuroimaging technique in temporal lobe epilepsy. It may detect small structural lesions and mesial temporal lobe sclerosis which are not easily seen with traditional CT scanning.

  17. MRI findings of serous atrophy of bone marrow and associated complications

    International Nuclear Information System (INIS)

    To report the MRI appearance of serous atrophy of bone marrow (SABM) and analyse clinical findings and complications of SABM. A retrospective search of MRI examinations of SABM was performed. Symptoms, underlying conditions, MRI findings, delay in diagnosis and associated complications were recorded. We identified 30 patients (15 male, 15 female; mean age: 46 ± 21 years) with MRI findings of SABM. Underlying conditions included anorexia nervosa (n = 10), cachexia from malignant (n = 5) and non-malignant (n = 7) causes, massive weight loss after bariatric surgery (n = 1), biliary atresia (n = 1), AIDS (n = 3), endocrine disorders (n = 2) and scurvy (n = 1). MRI showed mildly hypointense signal on T1- weighted and hyperintense signal on fat-suppressed fluid-sensitive images of affected bone marrow in all cases and similar signal abnormalities of the adjacent subcutaneous fat in 29/30 cases. Seven patients underwent repeat MRI due to initial misinterpretation of bone marrow signal as technical error. Superimposed fractures of the hips and lower extremities were common (n = 14). SABM occurs most commonly in anorexia nervosa and cachexia. MRI findings of SABM are often misinterpreted as technical error requiring unnecessary repeat imaging. SABM is frequently associated with fractures of the lower extremities. (orig.)

  18. MRI findings of serous atrophy of bone marrow and associated complications

    Energy Technology Data Exchange (ETDEWEB)

    Boutin, Robert D. [Department of Radiology, Sacramento, CA (United States); White, Lawrence M. [University of Toronto, Joint Department of Medical Imaging, Toronto General Hospital, Toronto, ON (Canada); Laor, Tal [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Spitz, Damon J. [New England Baptist Hospital, Department of Radiology, Boston, MA (United States); Lopez-Ben, Robert R. [Carolinas HealthCare System, Charlotte Radiology, Diagnostic Radiology, Charlotte, NC (United States); Stevens, Kathryn J. [Stanford University, Department of Radiology, Stanford, CA (United States); Bredella, Miriam A. [Massachusetts General Hospital and Harvard Medical School, Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Boston, MA (United States)

    2015-09-15

    To report the MRI appearance of serous atrophy of bone marrow (SABM) and analyse clinical findings and complications of SABM. A retrospective search of MRI examinations of SABM was performed. Symptoms, underlying conditions, MRI findings, delay in diagnosis and associated complications were recorded. We identified 30 patients (15 male, 15 female; mean age: 46 ± 21 years) with MRI findings of SABM. Underlying conditions included anorexia nervosa (n = 10), cachexia from malignant (n = 5) and non-malignant (n = 7) causes, massive weight loss after bariatric surgery (n = 1), biliary atresia (n = 1), AIDS (n = 3), endocrine disorders (n = 2) and scurvy (n = 1). MRI showed mildly hypointense signal on T1- weighted and hyperintense signal on fat-suppressed fluid-sensitive images of affected bone marrow in all cases and similar signal abnormalities of the adjacent subcutaneous fat in 29/30 cases. Seven patients underwent repeat MRI due to initial misinterpretation of bone marrow signal as technical error. Superimposed fractures of the hips and lower extremities were common (n = 14). SABM occurs most commonly in anorexia nervosa and cachexia. MRI findings of SABM are often misinterpreted as technical error requiring unnecessary repeat imaging. SABM is frequently associated with fractures of the lower extremities. (orig.)

  19. Incidental findings on MRI scans of patients presenting with audiovestibular symptoms

    OpenAIRE

    Khan Mohammad H; Papanikolaou Vasileios; Keogh Ivan J

    2010-01-01

    Abstract Background The evaluation of patients presenting with audiovestibular symptoms usually includes MRI of the internal auditory meatus, the cerebellopontine angle and the brain. A significant percentage of these scans will present unexpected, incidental findings, which could have important clinical significance. Objective To determine the frequency and clinical significance of incidental findings on MRI scans of patients with audiovestibular symptoms. Materials and methods A retrospecti...

  20. CORRELATION OF PAIN AND DISABILITY WITH MRI FINDINGS IN PATIENTS WITH LUMBAR DISCOGENIC BACK PAIN

    OpenAIRE

    Surendra K. Wani; Neha Deshpande

    2014-01-01

    Background: Lumbar disc prolapse is one of the common causes of low back pain seen in the working population. There are contradictorty reports regarding the clinical significance of various magnetic resonance imaging (MRI) findings observed in these patients. Purpose: The aim of the study was to determine the association of magnetic resonance imaging (MRI) findings with intensity of pain and self reported disability among persons with lumbar discogenic back pain. Material And M...

  1. Cyclic sciatica caused by infiltrative endometriosis: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Yekeler, Ensar; Kumbasar, Basak; Tunaci, Atadan; Barman, Ahmet; Tunaci, Mehtap [Department of Radiology, Istanbul Faculty of Medicine, Istanbul University, 34390, Capa, Istanbul (Turkey); Bengisu, Ergin [Department of Obstetrics and Gynecology, Istanbul Faculty of Medicine, Istanbul University, Istanbul (Turkey); Yavuz, Ekrem [Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, 34390, Capa, Istanbul (Turkey)

    2004-03-01

    Endometriosis, an important gynecological disorder of reproductive women, affects most commonly the ovaries and less frequently the gastrointestinal tract, chest, urinary tract, and soft tissues. Endometriosis classically appears on MRI as a mass with a large cystic component and variable signal intensities on T1- and T2-weighted images due to the presence of variable degradation of hemorrhagic products. Endometriosis in an atypical location, an infiltrative appearance and without cystic-hemorrhagic components has rarely been described. We report on a 33-year-old woman with cyclic sciatica due to histologically documented infiltrative endometriosis involving the area of the left sciatic notch. (orig.)

  2. An atypical case of noninfected iliopsoas bursitis - MRI findings.

    Science.gov (United States)

    Skiadas, Vasilios; Koutoulidis, Vasilios; Plotas, Athanasios

    2009-01-01

    The authors present an unusual case of atypical iliopsoas bursitis in an 81 years-old female patient. The patient asked for medical advice due to a chronic left hip and lower abdominal pain with no specific characteristics. Physical examination revealed a palpable left-sided pelvic mass. Ultrasound examination demonstrated a purely cystic mass that was presumed to be an ovarian cystic malignancy. The patient was referred for an MRI examination, which showed a cystic lesion extending from the left iliac crest to the anterior aspect of the ipsilateral hip joint (maximum diameter 18 cm), coursing below the iliopsoas tendon indicative of an extremely distended iliopsoas bursa. PMID:22470621

  3. Focal Pancreatitis Mimicking Pancreatic Mass: Magnetic Resonance Imaging (MRI)/Magnetic Resonance Cholangiopancreatography (MRCP) Findings Including Diffusion-Weighted MRI

    International Nuclear Information System (INIS)

    Background: Focal pancreatitis (FP) is a confined inflammation that mimics a pancreatic mass. Its imaging diagnosis is important to avoid unnecessary procedures. Purpose: To describe the spectrum of magnetic resonance imaging (MRI)/magnetic resonance cholangiopancreatography (MRCP) and diffusion-weighted MRI (DWI) findings of focal pancreatitis mimicking pancreatic masses. Material and Methods: Findings of MRI/MRCP including DWI with a b value of 0 and 600 s/mm2 in 14 patients with pancreatic masses on MRI were retrospectively reviewed and compared to normal pancreas in 14 patients as a control group. Results: FP revealed hypointense signal intensity (SI) (3/14), hypo- to isointense SI (7/14), or isointense SI (4/14) on T1-weighted images, and hypointense SI (1/14), isointense SI (5/14), iso- to hyperintense SI (7/14), or hyperintense SI (1/14) on T2-weighted images compared to remaining pancreas (RP). MRCP images revealed dilatation of the common bile duct (CBD) and main pancreatic duct (MPD) (5/14), dilatation of the MPD only (3/14), dilatation of the CBD only (3/14), and normal MPD and CBD (3/14). Both FP and RP revealed three types of time-signal intensity curves: 1) rapid rise to a peak, with a rapid decline (FP=2, RP=4), 2) slow rise to a peak, followed by a slow decline (FP=5, RP=4), and 3) slower rise to a peak, with a slow decline or plateau (FP=7, RP=6). Mean apparent diffusion coefficient (ADC) values for FP and RP were 2.09±0.18 and 2.03±0.2x10-3 mm2/s, respectively. ADC values of FP and RP revealed no significant difference. Conclusion: The spectrum of imaging findings of focal pancreatitis on MRI/MRCP including DWI was described. Findings of FP were not distinctive as compared to the remaining pancreas

  4. Focal Pancreatitis Mimicking Pancreatic Mass: Magnetic Resonance Imaging (MRI)/Magnetic Resonance Cholangiopancreatography (MRCP) Findings Including Diffusion-Weighted MRI

    Energy Technology Data Exchange (ETDEWEB)

    Momtahen, A.J.; Balci, N.C.; Alkaade, S.; Akduman, E.I.; Burton, F.R. (Depts. of Radiology and Gastroenterology, St. Louis Univ. Hospitals, St. Louis, MI (US))

    2008-06-15

    Background: Focal pancreatitis (FP) is a confined inflammation that mimics a pancreatic mass. Its imaging diagnosis is important to avoid unnecessary procedures. Purpose: To describe the spectrum of magnetic resonance imaging (MRI)/magnetic resonance cholangiopancreatography (MRCP) and diffusion-weighted MRI (DWI) findings of focal pancreatitis mimicking pancreatic masses. Material and Methods: Findings of MRI/MRCP including DWI with a b value of 0 and 600 s/mm2 in 14 patients with pancreatic masses on MRI were retrospectively reviewed and compared to normal pancreas in 14 patients as a control group. Results: FP revealed hypointense signal intensity (SI) (3/14), hypo- to isointense SI (7/14), or isointense SI (4/14) on T1-weighted images, and hypointense SI (1/14), isointense SI (5/14), iso- to hyperintense SI (7/14), or hyperintense SI (1/14) on T2-weighted images compared to remaining pancreas (RP). MRCP images revealed dilatation of the common bile duct (CBD) and main pancreatic duct (MPD) (5/14), dilatation of the MPD only (3/14), dilatation of the CBD only (3/14), and normal MPD and CBD (3/14). Both FP and RP revealed three types of time-signal intensity curves: 1) rapid rise to a peak, with a rapid decline (FP=2, RP=4), 2) slow rise to a peak, followed by a slow decline (FP=5, RP=4), and 3) slower rise to a peak, with a slow decline or plateau (FP=7, RP=6). Mean apparent diffusion coefficient (ADC) values for FP and RP were 2.09+-0.18 and 2.03+-0.2x10-3 mm2/s, respectively. ADC values of FP and RP revealed no significant difference. Conclusion: The spectrum of imaging findings of focal pancreatitis on MRI/MRCP including DWI was described. Findings of FP were not distinctive as compared to the remaining pancreas

  5. Cine club

    CERN Multimedia

    Cine club

    2015-01-01

    Wednesday 7 October 2015 at 20:00 CERN Council Chamber The Day of the Beast (El día de la bestia) Directed by Álex de la Iglesia Spain, 1995, 100 minutes A Basque priest finds by means of a cabalistic study of the Bible that the Antichrist is going to be born on Christmas Day in Madrid. Assisted by a heavy-metal fan and the host of a TV show on the occult, he will try to summon the Devil to find out the place of birth and kill the baby. Original version spanish; english subtitles   Wednesday 14 October 2015 at 20:00 CERN Council Chamber Tesis Directed by Alejandro Amenábar Spain, 1996, 125 minutes   Why is death and violence so fascinating? Is it morally correct to show violence in movies? If so, is there a limit to what we should show? That's the subject of Ángela's examination paper. She is a young student at a film school in Madrid. Together with the student Chema (who is totally obsessed with violent movies) they find a sn...

  6. Evaluation of atrial, ventricular and atrioventricular septal defects by cine magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Akagi, Teiji; Kato, Hirohisa; Kiyomatsu, Yumi; Saiki, Kuninobu; Suzuki, Kazushige; Eto, Takaharu (Kurume Univ., Fukuoka (Japan). School of Medicine)

    1992-06-01

    Cine magnetic resonance imaging (MRI) was performed on 20 patients (mean age: 5.3{+-}4.4 years) with atrial, ventricular, or atrioventricular septal defects for evaluation of cardiac structure and blood flow. Prior to cine MRI, electrocardiographycally gated MRI using multislice scquisition was performed on all patients to localize optimal slice location. Cine-MRI was obtained with a 30 deg flip angle, 15 msec echo time, and 30 msec pulse repetition time, on a 256 x 256 or 128 x 128 acquisition matrix. Abnormalities of cardiac structure were well defined in all patients by gated cardiac imaging. In 18 of the 20 patients, cine-MRI was able to detect shunt flow, visualized as a low intensity signal in comparison with the surrounding blood flow. Cine-MRI can provide not only accurate anatomy of cardiac structures but functional assessment of the cardiac chamber, wall topology and flow relations. Cine-MRI will become an important noninvasive technique for assessment of anatomy and physiology in congenital heart disease. (author).

  7. Dobutamine cine magnetic resonance imaging after myocardial infarction; Cine Risonanza Magnetica con dobutamina dopo infarto del miocardio

    Energy Technology Data Exchange (ETDEWEB)

    Giovagnoni, A.; Ligabue, G.; Romagnoli, R. [Modena Univ., Modena (Italy). Scienze Radiologiche, Dipt. di Medicina Interna; Reggio Emilia Univ., Reggio Emilia (Italy). Cattedra di Cardiologia; Rossi, R.; Muia, N.; Modena, M.G. [Modena Univ., Modena (Italy). Dipt. di Scienze Mediche, Oncologiche e Radiologiche; Reggio Emilia Univ. (Italy). Dipt. di Scienze Mediche, Oncologiche e Radiologiche

    1999-12-01

    Dobutamine Cine MRI is a new diagnostic imaging technique in the pretreatment (revascularization) assessment of myocardial infarction patients. In this issue are reported the result of a comparative study of the diagnostic yield of dobutamine Cine MRI with that of stress echocardiography in the assessment of viable myocardium. A new method for analysis of Cine MR images, employing digital subtraction, aimed at decreasing subjectivity in the quantitative assessment of myocardial wall thickening. Twenty-six patients (21 men and 5 women) with a history of myocardial infarction who were scheduled for revascularization were submitted to stress echocardiography and dobutamine Cine MRI to evaluate contractile recovery of the segments considered akinetic or hypo kinetic at baseline echocardiography. Dobutamine was administered in growing doses (5, 10, 15{gamma}/kg/min). 16 segments of the left ventricle in each patient were considered. In the 416 segments studied, it was found that 307 normo kinetic, 64 scarred and 45 viable segments with stress echocardiography, versus 302 normo kinetic, 83 scarred and 31 viable segments with dobutamine MRI. Three months after revascularization 15 patients were examined to check contractile recovery of the segments considered as viable. Echocardiography had 79% sensitivity and 97% specificity, while Cine MRI had 96% and 86%, respectively. In patients with anteroseptal wall myocardial infarction stress echocardiography had 75% sensitivity and 97% specificity. Echocardiography permits to distinguish viable myocardium and scarred myocardial tissue with good sensitivity and specificity, but Cine MRI performs better. Cine MRI has much higher sensitivity than stress echocardiography and thus makes the technique of choice to evaluate viable myocardium in these sites. The digital subtraction technique is as accurate as manual measurements, but reduces the error rate and permits quicker evaluation, particularly in subendocardial thickening. [Italian] La cine Risonanza Magnetica (cine RM) con stimolo farmacologico {beta}-adrenergico (stress dobutamina) rappresenta una nuova indagine diagnostica nella valuazione pretrattamento di rivascolarizzazione del paziente con infarto del miocardio. Scopo dello studio e' quello di verificare la validita' diagnostica della cine RM con stimolo farmacologico in confronto con l'ecocardiografia con stimolo farmacologico nella valutazione della vitalita' del miocardio e di proporre un nuovo metodo d'analisi delle immagini di cine RM mediante la sottrazione elettronica d'immagine al fine di ridurre gli elementi soggettivi nella valutazione quantitativa dell'ispessimento parietale. Ventisei pazienti (21 maschi, 5 femmine) con pregresso infarto del miocardio in attesa di intervento di rivascolarizzazione sono stati sottoposti a ecocardiografia con stimolo farmacologico mediante dobutamina e a esame cine RM con dobutamina al fine di verificare la ripresa contrattile dei segmenti giudicati acinetici o ipocinetici all'esame ecocardiografico di base. E' stata infusa dobutamina a dosi crescenti (5, 10, 15{gamma}/kg/min). Per ogni paziente sono stati considerati 16 segmenti del ventricolo sinistro. Nel totale di 416 segmenti miocardici considerati l'analisi qualitativa del movimento parietale con ecocardiografia con dobutamina ha dimostrato 307 segmenti normocinetici, 64 cicatriziali e 45 vitali mentre con la cine Rm sono stati osservati rispettivamente 302 segmenti come normocinetici, 83 cicatriziali e 31 vitali. Tre mesi dopo l'intervento di rivascolarizzazione 15 pazienti sono stati rivalutati per verificare la ripresa contrattile dei segmenti giudicati vitali. L'esame ecocardiografico ha mostrato sensibilita' del 79% e specificita' del 97% mentre per l'analisi qualitativa mediante cine RM la sensibilita' e' stata del 96% e la specificita' dell'86%. Nei pazienti con infarto anterosettale l'ecocardiografia con dobutamina ha dimostrato sensibilita' e specificita' rispetti

  8. Retroperitoneal Castleman's disease: US, CT and MRI findings

    International Nuclear Information System (INIS)

    Purpose: To describe de imaging features of this unusual localization of Castleman's disease. Materials and methods: Two patients (man: 62 years old, woman: 27 years old) with epigastric abdominal pain were studied. The physical examination was negative in the woman while in the other case a peri umbilical tumor was observed. The laboratory and the tumor markers were negative. Both patients had a history of appendectomy. US, TC and MRI were performed. After surgery the pathological examination included stain techniques with hematoxylin-eosin, Masson's techniques and PAS. Results: Retroperitoneal Castleman's disease in peri pancreatic localization (extremely rare). The US showed slight hypoechoic homogeneous lesions with clear rims. CT without contrast revealed isodense lesions and one of them presented a small calcification, the e.v. contrast CT showed a clear homogeneous reinforcement. MRI demonstrated hypointense lesions on T1, hyperintense on T2, and after the administration of gadolinium these lesions showed a marked reinforcement on the arterial phase, which persisted on the late venous phase. The differential diagnosis with pancreatic tumoral pathology was difficult. The pathological examination revealed a lymphoid angio follicular hyperplasia of hyaline vascular type. Conclusion: Retroperitoneal Castlelman's disease is a rare entity. The different imaging methods did not provide an accurate diagnosis of this entity since there are no pathognomonic features. The pathological examination was required to define the diagnosis in both reported cases. (author)

  9. MRI in the acute phase of spiral cord traumatic lesions: relationship between MRI findings and neurological outcome

    International Nuclear Information System (INIS)

    Purpose. To evaluate the role of emergency MRI in the diagnosis of acute spinal injuries, and to correlate the MRI pattern with the neurological outcome. Materials and methods. Thirty-eight patients with MRI-proven spinal cord injury were classified according to the Frankel classification. MRI was always performed within 8 hours from trauma. Frankel classification divides spinal cord injuries into 5 classes of decreasing severity based on the presence of motor and/or sensory function loss. On the basis of the MRI findings the patients were classified in 3 groups: group 1 (intramedullary haematoma), group 2 (multi-meta-mer oedema), group 3 (single-metamer oedema). All patients underwent neurosurgery and were clinically evaluated until the stabilization of neurological recovery. Mean follow-up lime was 12 months. The MR images were retrospectively evaluated and correlated to the neurological outcome. Results. Twenty eight patients showed complete motor loss (Frankel classes A and B); of these 28 patients 12 (42.8%) had MRI evidence of intramedullary haematoma, 12 (42.8%) had multi-metamer oedema and 4 (14.4%) had single-meta-mer oedema. Of the 10 patients with incomplete motor loss, none had MRI evidence of haemorrhage, 4 (40%) showed multi-metamer oedema and 6 (60%) showed single-meta-mer oedema. Follow-up clinical assessment revealed that 14/38 patients (36,8%) had clinical improvement and 2/38 cases (5%) had a complete motor recovery, as demonstrated by the move to a higher Frankel class. Conclusions. Our results, consistent with previous reports, confirm a strong correlation between the MRI appearance of traumatic spinal cord injuries in acute phase and long-term recovery of motor and sensory function: patients with initial haemorrhage had a poor prognosis, whereas those with spinal cord oedema had a good clinical outcome, as demonstrated by the passage to a higher Frankel class. MRI is particularly important in the initial evaluation of unconscious patients who cannot undergo a motor and sensory neurological evaluation, and to define the prognosis, which will influence the correct therapeutic choice

  10. Cine Club

    CERN Multimedia

    Ciné Club

    2013-01-01

    Thursday 22 August 2013 at 20:00 CERN Council Chamber The Angels’ Share Directed by Ken Loach (UK, 2012) Original version English; french subtitles; 101 minute This bitter sweet comedy follows protagonist Robbie as he sneaks into the maternity hospital to visit his young girlfriend Leonie and hold his newborn son Luke for the first time. Overwhelmed by the moment, he swears that Luke will not have the same tragic life he has had. Escaping a prison sentence by the skin of his teeth, he's given one last chance...While serving a community service order, he meets Rhino, Albert and Mo who, like him, find it impossible to find work because of their criminal records. Little did Robbie imagine how turning to drink might change their lives - not cheap fortified wine, but the best malt whiskies in the world. Will it be 'slopping out' for the next twenty years, or a new future with 'Uisge Beatha' the 'Water of Life?' Only the angels know.... Th...

  11. Lumbar Modic Changes - A Comparison Between Findings at Low-and High-field MRI

    DEFF Research Database (Denmark)

    Bendix, Tom; Sorensen, Joan S

    2012-01-01

    Study design A cross-sectional observational study. Objective To investigate if there is a difference in findings of lumbar Modic changes in low-field (0.3 Tesla) magnetic resonance imaging (MRI) as compared to high field (1.5 Tesla). Summary of background data It is a challenge to give patients with low back pain (LBP) a specific diagnosis. Modic changes as seen on MRI have been reported to be a possible source of pain. However, it is unclear if the diagnosis is independent on the field strength. Methods Twenty patients with Modic changes, 11 women and 9 men (mean age 53.6, range 29-81), with or without sciatica, seen in a Danish outpatient LBP clinic were included. All patients had MRI scans on both a high-field and a low-field MRI scanner. Two radiologists evaluated all lumbar endplates independently using a standardized evaluation protocol. Kappa statistics were used to analyze the inter-observer reproducibility. To analyze the difference between low- and high-field MRI we used paired t-test. Results The total number of Modic changes diagnosed with high-field MRI was significantly higher as compared to low-field MRI. However, 3-4 times as many Modic type 1 changes were found with low-field MRI as compared to high-field. Contrarily, with high-field MRI type 2 changes were diagnosed twice as often. Conclusion There was a significant difference between low- and high-field MRI regarding the overall prevalence of any Modic change, but this had opposite directions for type 1 and 2: Type 2 dominated in low field, and conversely in high field. The type of MRI unit should be taken into consideration when diagnosing patients with Modic changes.

  12. CINE CLUB

    CERN Multimedia

    CINE CLUB

    2010-01-01

    Thursday 7 October 2010 at 20:30 Jeudi 7 Octobre 2010 à 20:30 CERN Main Auditorium Amphithéâtre Principal Mystic River   By/de : Clint Eastwood (USA, 2003) 132 min With/avec : Sean Penn, Tim Robbins, Kevin Bacon, Laurence Fishburne, Marcia Gay Harden, Laura Linney   During a summer in 1975, Dave Boyle and two friends, Jimmy and Sean, are playing on a sidewalk in Boston when Dave is abducted by two men and subjected to sexual abuse over a period of several days. Eventually escaping, but haunted into adulthood by his trauma, Dave becomes a primary suspect when Jimmy's daughter, Katie, is found murdered. Sean, assigned to investigate the crime, finds himself facing both demons from the past and demons in the present as the circumstances surrounding Katie's death are uncovered.   Original version english with english subtitles Version originale anglaise soutitrée en anglais * * * * * * * Thursday 14 October 2010 at 20:30 ...

  13. CINE CLUB

    CERN Multimedia

    CINE CLUB

    2010-01-01

    Thursday 11 November 2010 at 20:30 / Jeudi 11 Novembre 2010 à 20:30 CERN Main Auditorium / Amphithéâtre Principal LE CHOCOLAT By/de : Lasse Hallström (UK/USA, 2000) 121 min With/avec: Lena Olin, Juliette Binoche, Johny Depp, Judi Dench, Alfred Molina, Peter Stormare, Leslie Caron, Carrie-Anne Moss   Vianne Rocher and her young daughter are drifters who are met with skepticism and resistance when they move to a conservative town in rural France and open a chocolate shop during Lent. As Vianne begins to work her magic and help those around her, the townspeople are soon won over by her exuberance and her delicious chocolates - except for the mayor, who is determined to shut her down. When a group of river drifters visit the town, Vianne teaches the townspeople something about acceptance, and finds love for herself along the way. Original version english / french with german subtitles Version originale anglaise / française soutitr&...

  14. ''Dropped-head'' syndrome due to isolated myositis of neck extensor muscles: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Gaeta, Michele; Mazziotti, Silvio; Blandino, Alfredo [University of Messina, Department of Radiological Sciences, Messina (Italy); Toscano, Antonio; Rodolico, Carmelo; Mazzeo, Anna [University of Messina, Department of Neurosciences, Psychiatry and Anaesthesiology, Messina (Italy)

    2006-02-15

    MRI findings of a patient with dropped-head syndrome due to focal myositis of the neck extensor muscles are presented. MRI showed oedematous changes and marked enhancement of the neck extensor muscles. After therapy MRI demonstrated disappearance of the abnormal findings. (orig.)

  15. Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings

    Science.gov (United States)

    Kragha, K. O.

    2015-01-01

    This is a case report of a 56-year-old male with hypertension who presented with urinary retention and bowel incontinence. CT and MRI of the abdomen and pelvis showed a large complex cystic and solid enhancing mass in the right presacral space. Pathology biopsy result showed malignant peripheral nerve sheath tumor (MPNST) with extensive necrosis. The diagnosis of MPNST is extremely difficult due to the lack of (1) conclusive immunohistochemistry or unique chromosomal anomaly, (2) universal distinctive histopathology, and (3) clinical criteria. The clinical, radiologic, and histologic presentation of MPNST is important in its diagnosis. A rare case of MPNST that produced urinary retention and bowel incontinence is presented that may aid clinicians in the diagnosis of this rare clinical entity. Motor weakness, central enhancement, and immunohistochemistry may assist in the diagnosis of MPNST and differentiation between benign peripheral nerve sheath tumor (BPNST) and MPNST. PMID:26634167

  16. Cine Club

    CERN Multimedia

    Ciné Club

    2011-01-01

    Wednesday 29 June 2011 at 20:30 CERN Council Chamber Arizona Dream  By/de : Emir Kusturica (USA/France, 1993) 142 min With/avec: Johnny Depp, Jerry Lewis, Fay Dunaway, Lily Taylor, Vincent Gallo A romantic comedy about the adventures of an innocent dreamer in the weird and colourful landscape of the American West. Caught between childhood and adulthood he finds himself back in his hometown where he becomes involved with a wealthy widow and her stepdaughter. Original version english; english subtitles Entrance : 2 CHF Projection from DVD http://cineclub.web.cern.ch/Cineclub/     Thursday 7 July 2011 at 20:30 CERN Council Chamber Burn After Reading  By/de : Ethan Coen and Joel Coen (USA/UK/France, 2008) 102 min With/avec: George Clooney, Frances McDormand, Brad Pitt, John Malkovich, Tilda Swinton Osbourne Cox, a Balkan expert, is fired at the CIA, so he begins a memoir. His wife wants a divorce and expects her lover, Harry, a philandering State Dep...

  17. Cine Club

    CERN Multimedia

    Cine Club

    2015-01-01

    Wednesday 21 October 2015 at 18:00 CERN Council Chamber Special screening in collaboration with CERN Social Media Back to the Future Part II Directed by Robert Zemeckis USA, 1989, 108 minutes Watch how the film-makers imagined we’d live in 2015, from flying cars to hydrated pizzas and much more, in this iconic film from the 1980s. Original version english; french subtitles   Wednesday 21 October 2015 at 20:00 CERN Council Chamber Timecrimes (Los Cronocrímenes) Directed by Nacho Vigalondo Spain, 2007, 92 minutes   A man accidentally gets into a time machine and travels back in time nearly an hour. Finding himself will be the first of a series of disasters of unforeseeable consequences. Original version spanish; english subtitles Wednesday 28 October 2015 at 20:00 CERN Council Chamber Snow White (Blancanieves) Directed by Pablo Berger Spain, 2012, 104 minutes A twist on the Snow White fairy tale that is set in 1920s Seville and centered on a female bullfighter. Ori...

  18. Cine club

    CERN Multimedia

    Ciné club

    2014-01-01

    Thursday 23 October 2014 at 20:00 CERN Council Chamber The Shop on Main Street Directed by Jan Kadar, Elmar Klos Slovakia, 1965, 125 minutes   In 1942, in a small town in Czechoslovakia, the poor carpenter Tony Brtko is assigned "Aryanizator" of a small shop on the main street by his fascist brother-in-law. His greedy wife is seduced with the promise of fortune, but Tony finds that the store owned by the deaf and senile seventy eight year-old widow Rozalie Lautmann is bankrupted and the old lady is financially supported by the Jewish community that promises a salary to him to help her. Tony befriends Mrs Lautmann and helps her in the store and repairs her furniture, and lures his wife with his salary. When the Jews are expelled from the town by the fascists, Tony decides to help the old lady. Original version Slovak; English subtitles   Thursday 30 October 2014 at 20:00 CERN Council Chamber High Noon Directed by Fred Zinnemann USA, 1952, 85 minutes On the ...

  19. Novel MRI finding for diagnosis of invasive placenta praevia: evaluation of findings for 65 patients using clinical and histopathological correlations

    Energy Technology Data Exchange (ETDEWEB)

    Ueno, Yoshiko; Kitajima, Kazuhiro; Maeda, Tetsuo; Suenaga, Yuko; Takahashi, Satoru; Sugimura, Kazuro [Kobe University Graduate School of Medicine, Department of Radiology, Kobe (Japan); Kawakami, Fumi [Kobe University Graduate School of Medicine, Department of Pathology, Kobe (Japan); Matsuoka, Shozo; Tanimura, Kenji; Yamada, Hideto [Kobe University Graduate School of Medicine, Department of Obstetrics and Gynaecology, Kobe (Japan); Ohno, Yoshiharu [Kobe University Graduate School of Medicine, Department of Radiology, Kobe (Japan); Kobe University Graduate School of Medicine, Advanced Biomedical Imaging Research, Kobe (Japan)

    2014-04-15

    To review established magnetic resonance (MR) criteria and describe a new MR finding for the diagnosis of invasive placenta praevia. A retrospective review of prenatal MRI examinations of 65 patients (median age: 35 years) who underwent MR for the screening of invasive placenta praevia. All MRIs were performed on a 1.5-T unit, including axial, coronal and sagittal T2-weighted half-Fourier single-shot turbo spin echo imaging. Fifteen patients were diagnosed with invasive placenta praevia. Two experienced radiologists reviewed the MR images and evaluated a total of six MRI features of the placenta, including our novel finding of the placental protrusion into the internal os (placental protrusion sign). Inter-rater reliability was assessed by using kappa statistics. Features with a kappa statistic >0.40 were evaluated using Fisher's two-sided exact test for comparison of their capabilities for placental invasion assessment. Interobserver reliability was moderate or better for the intraplacental T2 dark band, intraplacental abnormal vascularity, uterine bulging, heterogeneous placenta and placental protrusion sign. Fisher's two-sided exact test results showed all these features were significantly associated with invasive placenta praevia. The novel MRI finding of a placental protrusion sign is a useful addition to the established MRI findings for the diagnosis of invasive placenta praevia. (orig.)

  20. MRI findings in cervical spinal cord type II neurological decompression sickness: a case report.

    Science.gov (United States)

    Liow, M H; Ho, B H; Kim, S J; Soh, C R; Tang, K C

    2014-01-01

    Decompression illness affecting the cervical spinal cord is uncommon. We report a case that presented with mixed signs and symptoms of cervical myelopathy and Type II neurological decompression sickness. This presented a diagnostic dilemma that required the use of magnetic resonance imaging (MRI) scan to elucidate the underlying cause. Cervical spine MRI revealed the presence of tiny hypointensities and edema within the spinal cord that corresponded to the clinical findings. The patient recovered with residual neurological deficits after hy-perbaric oxygen (HBO2) therapy. To our knowledge, these MRI findings have yet to been described in literature and we recommend the use of MRI to assist diving physicians in the management of complex cases as long as it does not delay recompression. PMID:25562951

  1. MRI findings and clinical outcome in 45 divers with spinal cord decompression sickness.

    OpenAIRE

    Gempp, Emmanuel; Blatteau, Jean-Eric; Stephant, Eric; Pontier, Jean-Michel; Constantin, Pascal; Pény, Christophe

    2008-01-01

    BACKGROUND: Decompression sickness (DCS) affecting the spinal cord is the most dangerous form of diving-related injury with potential sequelae. This study was conducted to evaluate the relationship between spinal cord lesions on MRI and clinical findings in divers with spinal DCS. METHODS: We studied 45 cases of DCS that were referred to our hyperbaric facility with clinical evidence of spinal involvement during the period 2002-2007. The study included only patients who underwent MRI within 1...

  2. Detailed Shoulder MRI Findings in Manual Wheelchair Users with Shoulder Pain

    OpenAIRE

    Morrow, Melissa M. B.; Van Straaten, Meegan G.; Murthy, Naveen S.; Jonathan P. Braman; Elia Zanella; Zhao, Kristin D.

    2014-01-01

    Shoulder pain and pathology are common in manual wheelchair (MWC) users with paraplegia, and the biomechanical mechanism of injury is largely unknown. Establishing patterns of MRI characteristics in MWC users would help advance understanding of the mechanical etiology of rotator cuff disease, thus improving the logic for prescribed interventions. The purpose of this study was to report detailed shoulder MRI findings in a sample of 10?MWC users with anterolateral shoulder pain. The imaging ass...

  3. Identifying biological pathways in the MRI findings of people with low back pain

    DEFF Research Database (Denmark)

    Jensen, Rikke Krüger; Jensen, Tue Secher

    Title Identifying biological pathways in the MRI findings of people with low back pain Authors and affiliations Rikke K Jensen1, Tue Secher Jensen1, Per Kjaer1,2, Peter Kent1 1Research Department, Spine Centre of Southern Denmark, Hospital Lillebaelt, Institute of Regional Health Services Research, University of Southern Denmark, Part of the Clinical Locomotion Network, Middelfart, Denmark. 2Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Part of the Clinical Locomotion Network, Odense, Denmark Contact email rikke.kruger.jensen@slb.regionsyddanmark.dk Background Investigations into the association between lumbar MRI findings and low back pain (LBP) are complicated by multiple MRI findings being present at the same time. Findings such as lumbar intervertebral disc protrusions or endplate changes almost always co-exist with other degenerative disc findings such as the reduction of disc height and signal intensity. Despite this, the majority of previous research has focused solely on the associations between single imaging findings and pain or other clinical outcomes. Only recently have researchers started to engage with this complexity of MRI findings. An initial strategy to advance this area of investigation would be to recognise which MRI findings typically occur together and whether those clusters appear to reflect discrete biological pathways. Therefore, the objectives of this proof-of-concept study were to identify which vertebral MRI findings cluster together and describe plausible biological pathways that these clusters might represent. Methods All participants were people with chronic LBP seeking a comprehensive evaluation at an outpatient spine clinic in a Danish university hospital. Data for this study was extracted from the MRI findings of 631 people (3,155 lumbar spine motion segments) whose images were quantitatively coded using a detailed research protocol as part of the recruitment phase of two clinical trials. Reproducibility is high when using this MRI coding protocol (kappa 0.52-0.97). The MRI variables included in this study were information on intervertebral disc height and signal intensity, disc protrusions, high intensity zones, size and type of vertebral endplate signal changes, vertebral endplate irregularities and defects, osteophytes, and spondylolisthesis. Latent class analysis (probabilistic data mining) was used to distinguish the best fitting clusters of MRI findings. The distribution of lumbar disc levels in each cluster was also reported. Based on known histological changes inherent in the degeneration process of the motion segment, the clusters were grouped into hypothetical biological pathways. Results Latent class analysis identified twelve clusters of MRI findings. One cluster, characterised by no abnormal MRI findings, contained 52% of the motion segments and represented the normal, pre-degenerative motion segments. The following hypothetical pathways were derived from the content of the other clusters: (i) two clusters representing progressive stages of disc degeneration in the lower lumbar levels; (ii) four clusters representing progressive stages of disc protrusions and endplate changes in the lower lumbar levels; (iii) two cluster with endplate changes at either the upper or the lower endplates; (iv) two clusters containing progressive endplate changes and disc degeneration at the upper lumbar levels only; and lastly, (v) one cluster containing osteophytes at the upper lumbar motion segments. Conclusions MRI findings of lumbar vertebral motion segments were grouped into twelve clusters and those clusters fitted into a model of five different biological pathways of degeneration. Future research will test the association between these clusters and clinically important characteristics such as pain and activity limitation.

  4. Osteoskeletal manifestations of scurvy: MRI and ultrasound findings

    Energy Technology Data Exchange (ETDEWEB)

    Polat, Ahmet Veysel; Bekci, Tumay; Selcuk, Mustafa Bekir [Ondokuz Mayis University, Kurupelit, Department of Radiology, Faculty of Medicine, Samsun (Turkey); Say, Ferhat [Ondokuz Mayis University, Kurupelit, Department of Orthopaedics and Traumatology, Faculty of Medicine, Samsun (Turkey); Bolukbas, Emrah [Ondokuz Mayis University, Kurupelit, Department of Pediatrics, Faculty of Medicine, Samsun (Turkey)

    2015-08-15

    Scurvy has become very rare in the modern world. The incidence of scurvy in the pediatric population is extremely low. In the pediatric population, musculoskeletal manifestations are more common and multiple subperiosteal hematomas are an important indicator for the diagnosis of scurvy. Although magnetic resonance imaging findings of scurvy are well described in the literature, to our knowledge, ultrasound findings have not yet been described. In this article, we report a case of scurvy with associated magnetic resonance imaging and ultrasound findings. (orig.)

  5. Medulloblastoma with extensive nodularity: US, CT and MRI findings

    International Nuclear Information System (INIS)

    Medulloblastoma accounts for up to 25% of all paediatric CNS tumours. According to WHO classification (2007) medulloblastoma with extensive nodularity (MBEN) is a separate rare entity associated with younger age and better prognosis. A 9-month-old girl was admitted and examined because of macrocephaly and disturbed psychomotor development. Transfontanel ultrasound revealed dilated ventricular system and hyperechoic mass in the posterior cranial fossa. Computed tomography showed hyperdense mass in the cerebellum. Magnetic resonance imaging revealed a mass with gyriform pattern and strong contrast enhancement after gadolinium administration. Differential diagnosis included dysplastic heterotopic cortex, Lhermitte-Duclos disease, atypical teratoid/rhabdoid tumour (AT/RT), and medulloblastoma (MB). The patient was operated on. Medulloblastoma with extensive nodularity (MBEN) was finally diagnosed. The authors present and discuss three other cases of this rare entity.Transfontanel sonografic examination is capable of detection of the posterior fossa tumour as a cause of hydrocephalus and macrocephaly. The mass in a child's posterior cranial fossa that is hyperdense on unenhanced CT and gyriform, nodular, and markedly enhancing on MRI may strongly suggest medulloblastoma with extensive nodularity (MBEN). (authors)

  6. Neurovascular compression of cranial nerves: CT and MRI findings

    International Nuclear Information System (INIS)

    Purpose: The compression of a nervous structure by an aberrant vessel may be asymptomatic or produce an important symptoms, in these cases CT and MRI show relevant information. Materials and Methods: Between January 1998 and March 2001, we studied 27 patients: 8 with trigeminal neuralgia, 7 with hemi facial spasm, 4 vertigo and tinnitus, 2 hemianopsia, 1 with neuralgia of the amygdalin fossa, 1 with bitonal voice, 1 with tongue deviation with fascicular movements, 2 essential hypertension and 1 with severe headache. All of them had a neurologic evaluation from 2 specialists and 2 neuro radiologists interpreted the results. Results: The CT and RMI images with special sequences allowed to prove the compression of the entry segments of the V, VII, IX, X and XII cranial nerves, of the optic chiasma and the ventrolateral aspect of the medulla oblongata in close relation with the vasopressor centre. Also they demonstrate a rare vessel in the Silvio aqueduct avoiding the normal flow of the CSF. Of the total of patients that were studied, 37% had surgical confirmation. Conclusion: CT and RMI are sensitive and specific methods for the detection of vascular compressions of nervous structures. (author)

  7. MRI and SPECT findings as a predictive factor for postencephalitic epilepsy

    International Nuclear Information System (INIS)

    Relationship between postencephalitic epilepsy and acute phase symptoms, CSF, EEG and MRI findings was assessed by Kaplan-Meier method. Thirteen of 34 patients manifestated epilepsy including four intractable cases. Women (7/11), herpes simplex virus (6/7), seizures in acute phase (12/18), abnormal findings or MRI (6/7) were statistically significant. Four of nine patients with hyperperfusion area by HMPAO-SPECT in acute phase and two of three patients with hypoperfusion area by IMP-SPECT in recovery phase had epilepsy. Hyperperfusion in acute phase reflected acute seizures and inflammations, whereas hypoperfusion in the recovery phase reflected hypometabolism caused by brain damage. These findings suggest epileptogenicity, MRI and SPECT findings may predict prognosis of postencephalitic epilepsy. (author)

  8. Repaired supraspinatus tendons in clinically improving patients: Early postoperative findings and interval changes on MRI

    International Nuclear Information System (INIS)

    To demonstrate and further determine the incidences of repaired supraspinatus tendons on early postoperative magnetic resonance imaging (MRI) findings in clinically improving patients and to evaluate interval changes on follow-up MRIs. Fifty patients, who showed symptomatic and functional improvements after supraspinatus tendon repair surgery and who underwent postoperative MRI twice with a time interval, were included. The first and the second postoperative MRIs were obtained a mean of 4.4 and 11.5 months after surgery, respectively. The signal intensity (SI) patterns of the repaired tendon on T2-weighted images from the first MRI were classified into three types of heterogeneous high SI with fluid-like bright high foci (type I), heterogeneous high SI without fluid-like bright high foci (type II), and heterogeneous or homogeneous low SI (type III). Interval changes in the SI pattern, tendon thickness, and rotator cuff interval thickness between the two postoperative MRIs were evaluated. The SI patterns on the first MRI were type I or II in 45 tendons (90%) and type III in five (10%). SI decreased significantly on the second MRI (p < 0.050). The mean thickness of repaired tendons and rotator cuff intervals also decreased significantly (p < 0.050). Repaired supraspinatus tendons exhibited high SI in 90% of clinically improving patients on MRI performed during the early postsurgical period. The increased SI and thickness of the repaired tendon decreased on the later MRI, suggesting a gradual healing process rather than a retear.

  9. MRI findings in the liver of biliary atresia patients. Changes in postoperative course

    International Nuclear Information System (INIS)

    We studied the morphological changes in the liver in the postoperative course of biliary atresia (BA) patients by means of periodic MRI. Periodic MRI (every year) was done in 24 of 34 patients, who were operated on at our institute by hepatic portoenterostomy. For the 24 patients studied, we investigated the changes in liver morphology seen in the following MRI findings. Inflammation and fibrosis in the portal system areas: Fibrosis in the peripheral liver lobe: Atrophy of the liver lobe: Reconstructive change in the liver parenchyma. Three images, T1 weighted image (WI) with and without Gd-DTPA, and T2 WI, were taken in each examination. We also studied the correlation between the MRI findings and level of total bilirubin in serum. The results were as follows: The inflammation and fibrosis in the portal system areas were marked just after the operation, and then decreased during the 3-5 year postoperative period. The degree of other MRI findings gradually increased during the 3-5 year postoperative period. The degree of these MRI findings had not changed at the end of the 5th postoperative year. The extent of the MRI findings, except for that of peripheral liver atrophy, was correlated with the increase in the level of total bilirubin in serum. These results indicate that the inflammation and/or fibrosis either remained static or progressed in the liver of postoperative BA patients during the 3-5 year postoperative period, and that these changes in the liver become irreversible after the 5 year postoperative period. The morphological changes found in this study could reflect the pathogenesis in the liver of postoperative BA patients. (author)

  10. MRI findings in the liver of biliary atresia patients. Changes in postoperative course

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, Atsushi; Hatakeyama, Shinitsu; Suzuki, Norio; Kuroiwa, Minoru; Ikeda, Hitoshi; Tsuchida, Yoshiaki [Gunma Children' s Medical Center, Kitatachibana (Japan)

    2000-08-01

    We studied the morphological changes in the liver in the postoperative course of biliary atresia (BA) patients by means of periodic MRI. Periodic MRI (every year) was done in 24 of 34 patients, who were operated on at our institute by hepatic portoenterostomy. For the 24 patients studied, we investigated the changes in liver morphology seen in the following MRI findings. Inflammation and fibrosis in the portal system areas: Fibrosis in the peripheral liver lobe: Atrophy of the liver lobe: Reconstructive change in the liver parenchyma. Three images, T1 weighted image (WI) with and without Gd-DTPA, and T2 WI, were taken in each examination. We also studied the correlation between the MRI findings and level of total bilirubin in serum. The results were as follows: The inflammation and fibrosis in the portal system areas were marked just after the operation, and then decreased during the 3-5 year postoperative period. The degree of other MRI findings gradually increased during the 3-5 year postoperative period. The degree of these MRI findings had not changed at the end of the 5th postoperative year. The extent of the MRI findings, except for that of peripheral liver atrophy, was correlated with the increase in the level of total bilirubin in serum. These results indicate that the inflammation and/or fibrosis either remained static or progressed in the liver of postoperative BA patients during the 3-5 year postoperative period, and that these changes in the liver become irreversible after the 5 year postoperative period. The morphological changes found in this study could reflect the pathogenesis in the liver of postoperative BA patients. (author)

  11. Abnormal findings of magnetic resonance imaging (MRI) in patients with systemic lupus erythematosus involving the brain

    Energy Technology Data Exchange (ETDEWEB)

    Ishikawa, Akira; Okada, Jun; Kondo, Hirobumi (Kitasato Univ., Sagamihara, Kanagawa (Japan). School of Medicine); Kashiwazaki, Sadao

    1992-06-01

    To elucidate the clinical significance of MRI on central nervous system systemic lupus erythematosus (CNS-SLE), MRI and CT scans were performed in 35 patients with SLE, of 18 patients who had CNS manifestations at the time of MRI examinations. The investigations were also carried out in 17 patients without CNS-SLE. The rate of detection of abnormal findings on MRI in patients with CNS-SLE was 77.2% (14/18), which was high, as compared with the rate of those on CT scans (50%: 9/18). Especially, all of 4 patients with seizure and 3 patients with encephalopathy showed abnormal MRI findings, although respectively 50% and 33.3% of them had abnormal CT scan findings. MRI findings were classified into 4 groups below: (1) Large focal are as increased signal intensity at T2 weighted image. These were observed in 2 of 4 patients with seizure and 1 of 3 patients with encephalopathy, which were completely resolved after treatment. (2) Patchy subcortical foci of increased signal intensity at T2 weighted image. These were observed in 11 of 18 CNS-SLE and 7 of 17 without CNS-SLE, which were not detected by CT scan. (3) All of six patients with cerebral infarctions showed high signal intensity areas at T2 weighted image and low signal intensity areas at T1 weighted image. (4) Normal findings were observed in 4 of 18 CNS-SLE (22.2%). We concluded that MRI is useful for the evaluation of CNS-SLE and provides more information than CT scan. (author).

  12. Incidental findings on MRI scans of patients presenting with audiovestibular symptoms

    Directory of Open Access Journals (Sweden)

    Khan Mohammad H

    2010-06-01

    Full Text Available Abstract Background The evaluation of patients presenting with audiovestibular symptoms usually includes MRI of the internal auditory meatus, the cerebellopontine angle and the brain. A significant percentage of these scans will present unexpected, incidental findings, which could have important clinical significance. Objective To determine the frequency and clinical significance of incidental findings on MRI scans of patients with audiovestibular symptoms. Materials and methods A retrospective analysis of 200 serial MRI scans. Results Gender distribution: equal. Age range: 17-82 years. One-hundred and four scans (52% were normal and 1 scan (0.5% demonstrated a unilateral vestibular schwannoma. Ninety-five scans (47.5% demonstrated incidental findings. Sixty-six of these (33% were considered of ishaemic origin and did not require further action. Five (2.5% scans demonstrated significant findings which warranted appropriate referral; Two Gliomas (1%, 2 cases of extensive White Matter Lesions (1%, 1 lipoma (0.5%. The remaining scans demonstrated various other findings. Conclusion Investigation of patients with audiovestibular symptoms with MRI scans revealed incidental findings in a significant percentage (47.5%. The majority of these findings were benign warranting no further action and only 2.5% required further referral. It is the responsibility of the referring Otolaryngologist to be aware of these findings, to be able to assess their significance, to inform the patient and if needed to refer for further evaluation.

  13. MRI findings and sensorimotor development in infants with bilateral spastic cerebral palsy.

    Science.gov (United States)

    Cioni, G; Di Paco, M C; Bertuccelli, B; Paolicelli, P B; Canapicchi, R

    1997-06-01

    The correlation between MRI findings and sensorimotor development was investigated in a group of 48 infants with bilateral spastic cerebral palsy (CP). The ages at MRI examination and cognitive assessment were fairly homogeneous (mean 15 months and 17 months, respectively). The following MRI parameters were scored: size of lateral ventricles, extension of white matter lesions and of white matter reduction, thinning of corpus callosum, presence and size of cystic areas, dimension of subarachnoid spaces and presence of cortical abnormalities. Cognitive assessment included Griffiths Developmental Scales and Uzgiris-Hunt Scales. The patients were subdivided into six classes according to intellectual level (DSM-III-R). For the whole group a highly significant correlation was found between all MRI parameters and the level of cognitive development. This result was probably due to the inclusion of 14 untestable, severely mentally retarded infants, who showed very severe MRI abnormalities. However, when the untestable infants were excluded from the analysis, it was the presence of cysts and the entity of white matter reduction that correlated with both Griffiths Scales and Uzgiris-Hunt Scales. These results indicate the clinical value of MRI findings and particularly of white matter abnormalities for early identification of sensorimotor impairment in infants with bilateral spastic CP. PMID:9187473

  14. MRI findings in an infant with vaccine-associated paralytic poliomyelitis

    Energy Technology Data Exchange (ETDEWEB)

    Lopes Ferraz-Filho, Jose Roberto [Sao Jose do Rio Preto Medical School, Department of Radiology, Hospital de Base, Sao Paulo, State (Brazil); Sao Jose do Rio Preto Medical School, Department of Radiology, Sao Jose do Rio Preto, Sao Paulo State (Brazil); Santos Torres, Ulysses dos; Portela de Oliveira, Eduardo; Soares Souza, Antonio [Sao Jose do Rio Preto Medical School, Department of Radiology, Hospital de Base, Sao Paulo, State (Brazil)

    2010-12-15

    Although acute flaccid paralysis is a manifestation observed in several neurologic and muscular disorders, vaccine-associated paralytic poliomyelitis (VAPP) is an exceedingly rare etiology. In the clinical setting of acute flaccid paralysis, MRI is useful in differentiating between VAPP and other conditions. Additionally, MRI can assess the extent of lesions. However, reports on MRI findings in VAPP are scarce in the pediatric radiology literature. We report a Brazilian infant who developed VAPP 40 days after receiving the first dose of oral polio vaccine (OPV). MR images of the cervical and thoracic spinal cord showed lesions involving the anterior horn cell, with increased signal intensity on T2-weighted sequences. We would like to emphasize the importance of considering VAPP as a differential diagnosis in patients with acute flaccid paralysis and an MRI showing involvement of medulla oblongata or spinal cord, particularly in countries where OPV is extensively administered. (orig.)

  15. MRI findings in an infant with vaccine-associated paralytic poliomyelitis

    International Nuclear Information System (INIS)

    Although acute flaccid paralysis is a manifestation observed in several neurologic and muscular disorders, vaccine-associated paralytic poliomyelitis (VAPP) is an exceedingly rare etiology. In the clinical setting of acute flaccid paralysis, MRI is useful in differentiating between VAPP and other conditions. Additionally, MRI can assess the extent of lesions. However, reports on MRI findings in VAPP are scarce in the pediatric radiology literature. We report a Brazilian infant who developed VAPP 40 days after receiving the first dose of oral polio vaccine (OPV). MR images of the cervical and thoracic spinal cord showed lesions involving the anterior horn cell, with increased signal intensity on T2-weighted sequences. We would like to emphasize the importance of considering VAPP as a differential diagnosis in patients with acute flaccid paralysis and an MRI showing involvement of medulla oblongata or spinal cord, particularly in countries where OPV is extensively administered. (orig.)

  16. Perianal disease in pediatric Crohn disease: a review of MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Compton, Gregory L.; Bartlett, Murray [Royal Children' s Hospital, Medical Imaging Department, Parkville, Victoria (Australia)

    2014-10-15

    Perianal complications of Crohn disease are a common occurrence in children and can result in significant morbidity when not accurately characterized prior to surgical intervention. MRI is an excellent imaging modality for the evaluation of perianal inflammatory bowel disease - allowing characterization and detailed description of perianal fistulas. MRI has many advantages over other imaging modalities for the pediatric patient. Radiologists will benefit from a sophisticated understanding of perianal anatomy, the classification of perianal fistulas, the advantages MRI offers in characterization of perianal fistulas as well as the common and incidental findings that are important in the MRI evaluation of perianal inflammatory bowel disease in children. Perianal fistulas are found at a high rate in pediatric referrals and are more commonly found in male patients. (orig.)

  17. MRI findings in the liver in biliary atresia patients after the Kasai operation

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, Atsushi; Hatakeyama, Shin-itsu; Suzuki, Norio; Kuroiwa, Minoru; Ikeda, Hitoshi; Murakami, Jun; Sakurai, Minako; Matsuyama, Shiro; Tsuchida, Yoshiaki [Gunma Children`s Medical Center, Hokkitsu (Japan)

    1997-01-01

    To evaluate liver function in biliary atresia (BA) patients after the Kasai operation, MRI was carried out 28 times in 19 BA patients. Sixteen of these were divided into three groups. In group 1 (n=7) the t-bil was continuously kept under 1 mg/100 ml. In group 2 (n=4) the t-bil was continuously kept under 1 mg/100 ml, but GPT and {gamma}-GTP remained high for more than 2 years. In group 3 (n=5) an increase in the t-bil level reappeared (1-2 mg/100 ml; n=4, >2 mg/100 ml; n=1). The differences between MRI finding in the 3 groups, and the correlation between MRI findings and laboratory data (t-bil, ChE, GPT and {gamma}-GTP), which were taken around the time of MRI examinations, were studied. All 19 patients had normal or high signal areas of various sizes on T1 weighted images (WI). Eighteen of 19 patients had high signal areas of various sizes on T2 WI in the portal system areas and/or liver parenchyma, and these areas were enhanced by gadolinium-DTPA in about half of the patients. Ten of 16 patients had atrophic change over one liver lobe. MRI findings for group 1 and the other groups were significantly different, and MRI findings, except for atrophic change, were correlated with the increase or decrease in laboratory data taken around the time of MRI examinations. These results indicate that a normal or high signal area on T1 WI shows functional tissue, and that a high signal area on T2 WI shows tissue damaged by inflammation and/or progressive fibrosis. (K.H.)

  18. MRI findings in the liver in biliary atresia patients after the Kasai operation

    International Nuclear Information System (INIS)

    To evaluate liver function in biliary atresia (BA) patients after the Kasai operation, MRI was carried out 28 times in 19 BA patients. Sixteen of these were divided into three groups. In group 1 (n=7) the t-bil was continuously kept under 1 mg/100 ml. In group 2 (n=4) the t-bil was continuously kept under 1 mg/100 ml, but GPT and ?-GTP remained high for more than 2 years. In group 3 (n=5) an increase in the t-bil level reappeared (1-2 mg/100 ml; n=4, >2 mg/100 ml; n=1). The differences between MRI finding in the 3 groups, and the correlation between MRI findings and laboratory data (t-bil, ChE, GPT and ?-GTP), which were taken around the time of MRI examinations, were studied. All 19 patients had normal or high signal areas of various sizes on T1 weighted images (WI). Eighteen of 19 patients had high signal areas of various sizes on T2 WI in the portal system areas and/or liver parenchyma, and these areas were enhanced by gadolinium-DTPA in about half of the patients. Ten of 16 patients had atrophic change over one liver lobe. MRI findings for group 1 and the other groups were significantly different, and MRI findings, except for atrophic change, were correlated with the increase or decrease in laboratory data taken around the time of MRI examinations. These results indicate that a normal or high signal area on T1 WI shows functional tissue, and that a high signal area on T2 WI shows tissue damaged by inflammation and/or progressive fibrosis. (K.H.)

  19. An experimental study on image findings of MRI and their pathomorphological basis in limb gunshot wound

    International Nuclear Information System (INIS)

    Objective: To observe the MRI findings of limb gunshot wound and investigate their pathomorphological basis through animal models. Methods: Sixteen mongrel dogs were divided into four groups randomly. The hind legs of dogs shot with handgun were undergone 0.5 T MRI scans at 5 h, 24 h, 48 h, and 72 h after wounded, respectively. The gross changes, HE staining light microscopic findings and MRI findings of wounds were observed. Results: Permanent tract was a zone of tissue defect. In the tract, blood of 5 h group's and pus of 24 h, 48 h, and 72 h groups showed T1WI hypointense signal and T2WI hyperintense signal. In contusion zone, the main pathological change was homogeneous coagulating necrosis of muscle fibers. MRI images showed irregular line, dot, or block T1WI isointense signal, T2WI hypointense signal, and no enhanced after Gd-DTPA injected in all groups. In concussion zone, the main pathological changes of 5 h group were edema, degeneration, and lysis of cells and lots of erythrocytes in the tissue interspace. Besides these, a large quantity of leucocytes and pus cells appeared, the lysis of degenerated cells near the contusion zone and the edema of such area, with passage of time, were more obviously in groups 24 h, 48 h, and 72 h. In MRI, concussion zone showed slightly hypointense T1WI signal, hyperintense T2WI, signal and T2WI signal got higher and the adjacent contusion zone got clearer with time pass. Concussion zone could be enhanced obviously. Conclusion: MRI can reflect the lesion of tissue in limb gunshot wound accurately during seventy-two hours after wound. The T2WI and contrast-enhanced T1WI are valuable. The special tissue-defect area, coagulating necrosis of cells, and large range injury of blood vessels and cells are the important pathomorphological basis which cause the MRI findings of gunshot wound different from normal trauma. (author)

  20. Brain MRI findings in patients with initial cerebral thrombosis and the relationship between incidental findings, aging and dementia

    International Nuclear Information System (INIS)

    To estimate the relationship between aging, dementia and changes observed on magnetic resonance imaging (MRI) seen in elderly patients with cerebral thrombosis, MRI findings in 103 patients with an initial stroke event (thrombosis group) were compared with those of 37 patients with hypertension/diabetes (high risk group) and 78 patients without those disorders (low risk group). In addition to the causative lesions in the thrombosis group, periventricular hyperintensities (PVH), spotty lesions (SL), silent infarctions (SI), ventricular dilatation (VD), and cortical atrophy (CA) were analyzed in these groups. Infarctions located in the internal capsule/corona radiata were the most frequent causative lesion. Compared to the low risk group, a high incidence of patchy/diffuse PVH, SI, and severe CA was seen in both the thrombosis group and the high risk group. Widespread PVH and multiple SL increased with age in the thrombosis group, while severe CA was seen in each group. SI and VD tended to increase after age 60, though they were not significant. Dementia, diagnosed in 40 out of 78 patients, increased with age. Multivariate analysis revealed the degree of the effects of MRI findings on dementia to be marked in PVH, brain atrophy, causative lesions, and SL, in that order. These results indicated that diffuse PVH and brain atrophy, developing with age, promoted dementia in the elderly with vascular lesions. Moreover, they suggested that a variety of silent brain lesions recognized on MRI other than infarction can affect symptoms in the elderly. (author)

  1. Cine magnetic resonance imaging in hypertrophic cardiomyopathy. Evaluation of left ventricular wall thickness and systolic function

    Energy Technology Data Exchange (ETDEWEB)

    Ishino, Yoichi; Nakamura, Katsumi; Egashira, Kannji; Nakata, Hajime [University of Occupational and Environmental Health, Kitakyushu, Fukuoka (Japan)

    1996-09-01

    Cine magnetic resonance imaging (MRI) was performed on 21 patients with hypertrophic cardiomyopathy and left ventricular (LV) regional systolic function was quantitatively evaluated. The visual evaluation of hypertrophic regions and the motion patterns of their walls on cine MR images was possible in most cases. However, this evaluation was subjective and a quantitative analysis was difficult. Septal and posterior wall thickness measured on cine MRI correlated well with those obtained by ultrasound cardiogram (UCG). There was also a good correlation between % thickness of LV wall and its thickness at end diastolic phase. Comparison of % thickness between normal subjects and hypertrophic cardiomyopathies showed a tendency of it being less at the region of more severe hypertrophic change. We conclude that cine MRI is a useful means to analyse the anatomical feature and functional change in hypertrophic cardiomyopathy. (author)

  2. Incidental findings at MRI-enterography in patients with suspected or known Crohn’s disease

    Directory of Open Access Journals (Sweden)

    Michael Dam Jensen, Torben Nathan, Jens Kjeldsen, Søren Rafael Rafaelsen

    2010-01-01

    Full Text Available AIM: To determine the frequency and clinical impact of incidental findings detected with magnetic resonance imaging (MRI-enterography in patients with suspected or known Crohn’s disease (CD.METHODS: Incidental findings were defined as unexpected lesions outside the small intestine, not previously known or suspected at the time of referral, and not related to inflammatory bowel disease. Through a systematic review of medical charts we analyzed the clinical impact of incidental findings, and compared the MRI findings with subsequent diagnostic procedures.RESULTS: A total of 283 patients were included in the analysis, and MRI detected active CD in 31%, fistula in 1.4% and abscess in 0.7%. Extra-intestinal findings not related to CD were recorded in 72 patients (25%, of which 58 patients (20% had 74 previously unknown lesions. Important or incompletely characterized findings were detected in 17 patients (6.0%. Incidental findings led to 12 further interventions in 9 patients (3.2% revealing previously unknown pathological conditions in 5 (1.8%. One patient (0.4% underwent surgery and one patient was diagnosed with a malignant disease. MRI detected incidental colonic lesions in 16 patients of which additional work-up in 4 revealed normal anatomy. Two patients (0.7% benefitted from the additional examinations, whereas incidental findings led to unnecessary examinations in 9 (3.2%.CONCLUSION: In a minority of patients with suspected or known CD, important incidental findings are diagnosed at MRI-enterography. However, a substantial number of patients experience unnecessary morbidity because of additional examinations of benign or normal conditions.

  3. Incidental findings at MRI-enterography in patients with suspected or known Crohn’s disease

    Science.gov (United States)

    Jensen, Michael Dam; Nathan, Torben; Kjeldsen, Jens; Rafaelsen, Søren Rafael

    2010-01-01

    AIM: To determine the frequency and clinical impact of incidental findings detected with magnetic resonance imaging (MRI)-enterography in patients with suspected or known Crohn’s disease (CD). METHODS: Incidental findings were defined as unexpected lesions outside the small intestine, not previously known or suspected at the time of referral, and not related to inflammatory bowel disease. Through a systematic review of medical charts we analyzed the clinical impact of incidental findings, and compared the MRI findings with subsequent diagnostic procedures. RESULTS: A total of 283 patients were included in the analysis, and MRI detected active CD in 31%, fistula in 1.4% and abscess in 0.7%. Extra-intestinal findings not related to CD were recorded in 72 patients (25%), of which 58 patients (20%) had 74 previously unknown lesions. Important or incompletely characterized findings were detected in 17 patients (6.0%). Incidental findings led to 12 further interventions in 9 patients (3.2%) revealing previously unknown pathological conditions in 5 (1.8%). One patient (0.4%) underwent surgery and one patient was diagnosed with a malignant disease. MRI detected incidental colonic lesions in 16 patients of which additional work-up in 4 revealed normal anatomy. Two patients (0.7%) benefitted from the additional examinations, whereas incidental findings led to unnecessary examinations in 9 (3.2%). CONCLUSION: In a minority of patients with suspected or known CD, important incidental findings are diagnosed at MRI-enterography. However, a substantial number of patients experience unnecessary morbidity because of additional examinations of benign or normal conditions. PMID:20039452

  4. Evaluation of MRI findings in non-specific inflammatory processes in the parasellar region

    International Nuclear Information System (INIS)

    We report the MRI findings on 6 patients with a non-specific inflammatory process in the parasellar region. Ophthalmoplegia developed in all patients. Only two patients complained of boring pain behind the eye and one of mild headache. The other three patients did not complain of pain. MRI clearly showed the extent of the lesions. In two patients the lesion was localized in the cavernous sinus. In the other patients, the lesions extended to the orbital apex, intrasellar and suprasellar regions, infratemporal fossa, or other neighboring regions beyond the cavernous sinus. The signal intensity of the lesions on T2WI was variable. The lesions were significantly enhanced after administration of Gd-DTPA. They were non-homogeneously enhanced in some patients. In three patients the lesions were well enhanced on the initial MRI scans. However, they were less enhanced on subsequent follow-up MRI or CT. The signal intensity and the degree of enhancement may vary substantially during the evolution of the inflammatory process or by blood flow in the cavernous sinus. Painful ophthalmoplegia is encountered in diseases of diverse pathogenesis in which the signal intensity and the extent of the lesions are variable. The MRI findings in one patient were not different from those of perineural spread from extracranial lesions, especially the one in the nasopharynx. However, MRI showed no abnormality in the nasopharynx and the base of the skull. In this patient, the clinical symptoms and MRI findings improved spontaneously. In some patients, the clinical symptoms and the extent of the pathological process were different from those in the classic Tolosa-Hunt syndrome. It could be suggested that the spectrum of non-specific inflammatory processes in the parasellar region is wider than the criteria for classic Tolosa-Hunt syndrome. (J.N.M.)

  5. Association between spondlyloarthritis features and MRI findings in patients with persistent low back pain

    DEFF Research Database (Denmark)

    Arnbak, Bodil; Jurik, Anne Grethe

    2014-01-01

    Introduction and Aim. This study was based on the assumption that clinical and MRI finding which are strongly associated with the spondyloarthritis (SpA) disease entity, also are associated with each other. Therefore the objectives were to explore the prevalence of clinical SpA features and MRI findings and the association between these two domains. Methods. The study sample included patients aged 18-40 years with persistent low back pain, referred to a public Spine Centre. The prevalence of and associations between clinical SpA features (incl. HLA-B27and CRP) and MRI of the entire spine and sacroiliac joints (SIJ) were estimated and analysed. Results. Of the 1020 patients included in the study, 52% had ?1 clinical SpA feature. The three most common SpA features were; inflammatory back pain, good response to NSAID and family disposition (15-17% each). SIJ bone marrow oedema (BMO) occurred in 21%. Although several SpA features, incl. HLAB27, were positively associated with MRI findings at the SIJ (OR ranging from 1.1-9.0), the three most common clinical SpA features were not. Several SIJ and spinal MRI findings, incl. severe SIJ BMO (sum-scores ?3) and SIJ erosions, were associated with positive HLA-B27 (OR ranging from 3.1-24.5). Slight BMO (sum-score of 1) was, however, not associated with any SpA features. Conclusions. The high prevalence of both clinical SpA features and MRI findings and the lack of consistent associations between the two domains, indicate a need for further investigation of the diagnostic utility of SpA features and the minimum requirements of BMO for defining sacroiliitis.

  6. Do MRI findings identify patients with low back pain or sciatica who respond better to particular interventions?

    DEFF Research Database (Denmark)

    Steffens, Daniel; Hancock, Mark J; Pereira, Leani S M; Kent, Peter M; Latimer, Jane; Maher, Chris G

    2015-01-01

    PURPOSE: Magnetic resonance imaging (MRI) can reveal a range of degenerative findings and anatomical abnormalities; however, the clinical importance of these remains uncertain and controversial. We aimed to investigate if the presence of MRI findings identifies patients with low back pain (LBP) or sciatica who respond better to particular interventions. METHODS: MEDLINE, EMBASE and CENTRAL databases were searched. We included RCTs investigating MRI findings as treatment effect modifiers for pati...

  7. MRI findings in soccer players with long-standing adductor-related groin pain and asymptomatic controls

    DEFF Research Database (Denmark)

    Branci, Sonia; Thorborg, Kristian; Bech, Birthe Højlund; Boesen, Mikael; Nielsen, Michael Bachmann; Hölmich, Per

    2015-01-01

    BACKGROUND: Soccer players are commonly affected by long-standing adductor-related groin pain (ARGP), but the clinical significance of MRI findings in these athletes is largely unknown. Our aims were (1) to evaluate whether MRI findings are associated with long-standing ARGP in soccer players, (2) to assess MRI findings in asymptomatic soccer players and non-soccer playing controls. METHODS: This cross-sectional study included 28 male soccer players with long-standing ARGP, 17 male asymptomatic ...

  8. MRI findings in patients with defecatory dysfunction after surgical correction of anorectal malformation

    International Nuclear Information System (INIS)

    Postoperative anorectal malformation patients frequently have defecatory dysfunction. MRI may be useful in the management of these patients. To analyze static and dynamic MRI findings in patients with defecatory dysfunction after correction of anorectal malformation (ARM), and compare differences between patients with constipation and fecal incontinence. Pelvic MRI studies of 20 constipated and 32 incontinent postoperative ARM patients were analyzed retrospectively to determine the location and morphology of the neorectum, presence of peritoneal fat herniation, presence of scarring, development of the striated muscle complex (SMC) and any other abnormalities. The two groups were then compared using ? 2-test. Eighteen patients also underwent MRI defecography to evaluate pelvic floor function and abnormalities are reported. The children with incontinence were more likely to have abnormal location of the neorectum (P = 0.031), increased anorectal angle (ARA) (P = 0.031) and peritoneal fat herniation (P = 0.032), and less likely to have dilation of the neorectum (P = 0.027), than the children with constipation. There were no significant differences between the two groups in incidence of focal stenosis of the neorectum (P = 0.797), presence of extensive scarring (P = 0.591) and developmental agenesis of the SMC (P > 0.05). MRI defecography showed 6 anterior rectoceles, 6 cystoceles and 18 pelvic floor descents. MRI is a helpful imaging modality in postoperative ARM patients with defecatory dysfunction, and it shows distinct differences between the children with constipation and incontinence and provides individualized information to guide further treatment. (orig.)

  9. Neuroradiological findings in primary progressive aphasia: CT, MRI and cerebral perfusion SPECT

    International Nuclear Information System (INIS)

    Primary progressive aphasia (PPA) is defined as progressive decline in language for 2 or more years with preservation of activities of daily living and general cognitive functions. Whereas the clinical features of this syndrome have been well documented, the neuroradiological findings have not been studied systematically. We studied 13 patients with PPA retrospectively: 10 underwent CT, 12 MRI and 12 cerebral perfusion studies using 99mTc-HMPAO SPECT. CT and MR images were scored for focal atrophy by two independent assessors. Initial qualitative assessment of SPECT images was confirmed by quantitative analysis. CY was normal in 5 patients. Focal atrophy, affecting predominantly the left temporal lobe, was seen in 4 of 10 patients on CT, and 10 of 12 on MRI. Atrophy was localised primarily to the superior and middle temporal gyri on MRI. All 12 patients who underwent SPECT had unilateral temporal lobe perfusion defects, in 2 patients of whom MRI was normal. CT is relatively insensitive to focal abnormalities in PPA; MRI and SPECT are the imaging modalities of choice. MRI allows accurate, specific localisation of atrophy with the temporal neocortex. SPECT may reveal a functional decrease in cerebral perfusion prior to establishment of structural change. (orig.)

  10. Unexpected MRI findings in clinically suspected Legg-Calve-Perthes disease

    Energy Technology Data Exchange (ETDEWEB)

    Lobert, Philip F.; Dillman, Jonathan R.; Strouse, Peter J.; Hernandez, Ramiro J. [University of Michigan Health System, Department of Radiology, Section of Pediatric Radiology, C.S. Mott Children' s Hospital/F3503, Ann Arbor, MI (United States)

    2011-03-15

    In the setting of clinically suspected Legg-Calve-Perthes (LCP) disease and negative/equivocal radiographs, contrast-enhanced MRI can be performed to confirm the diagnosis. To determine the frequency of unexpected causes of hip pain as identified by MRI in children with clinically suspected LCP disease and negative/equivocal radiographs. All pediatric contrast-enhanced MRI examinations of the pelvis and hips performed between January 2000 and February 2009 to evaluate for possible LCP disease in the setting of negative/equivocal radiographs were identified. MRI examinations performed to evaluate for secondary avascular necrosis were excluded. Imaging reports were retrospectively reviewed for unexpected clinically important causes of hip pain. Thirty-six pediatric patients underwent contrast-enhanced MRI examinations for clinically suspected LCP disease in the setting of negative/equivocal radiographs. Twenty-two (61%) imaging studies were normal, while four (11%) imaging studies demonstrated findings consistent with LCP disease. Ten (28%) imaging studies revealed unexpected clinically important causes of hip pain, including nonspecific unilateral joint effusion and synovitis (n = 7, juvenile chronic arthritis was eventually diagnosed in 3 patients), sacral fracture (n = 1), apophyseal injury (n = 1), and femoral head subluxation (n = 1). MRI frequently reveals unexpected clinically important causes of hip pain in children with suspected LCP disease and negative/equivocal radiographs. (orig.)

  11. MRI findings in patients with defecatory dysfunction after surgical correction of anorectal malformation

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Yong; Shao, Guang-rui [Second Hospital of Shandong University, Department of Radiology, Jinan (China); Wang, Ruo-yi [Second Hospital of Shandong University, Department of Pediatric Surgery, Jinan (China); Zhang, Yuan [Second Hospital of Shandong University, Evidence-based Medical Center, Jinan (China); Zhang, Shu-hui [Second Hospital of Shandong University, Department of Laboratory, Jinan (China)

    2013-08-15

    Postoperative anorectal malformation patients frequently have defecatory dysfunction. MRI may be useful in the management of these patients. To analyze static and dynamic MRI findings in patients with defecatory dysfunction after correction of anorectal malformation (ARM), and compare differences between patients with constipation and fecal incontinence. Pelvic MRI studies of 20 constipated and 32 incontinent postoperative ARM patients were analyzed retrospectively to determine the location and morphology of the neorectum, presence of peritoneal fat herniation, presence of scarring, development of the striated muscle complex (SMC) and any other abnormalities. The two groups were then compared using {chi} {sup 2}-test. Eighteen patients also underwent MRI defecography to evaluate pelvic floor function and abnormalities are reported. The children with incontinence were more likely to have abnormal location of the neorectum (P = 0.031), increased anorectal angle (ARA) (P = 0.031) and peritoneal fat herniation (P = 0.032), and less likely to have dilation of the neorectum (P = 0.027), than the children with constipation. There were no significant differences between the two groups in incidence of focal stenosis of the neorectum (P = 0.797), presence of extensive scarring (P = 0.591) and developmental agenesis of the SMC (P > 0.05). MRI defecography showed 6 anterior rectoceles, 6 cystoceles and 18 pelvic floor descents. MRI is a helpful imaging modality in postoperative ARM patients with defecatory dysfunction, and it shows distinct differences between the children with constipation and incontinence and provides individualized information to guide further treatment. (orig.)

  12. Unexpected MRI findings in clinically suspected Legg-Calve-Perthes disease

    International Nuclear Information System (INIS)

    In the setting of clinically suspected Legg-Calve-Perthes (LCP) disease and negative/equivocal radiographs, contrast-enhanced MRI can be performed to confirm the diagnosis. To determine the frequency of unexpected causes of hip pain as identified by MRI in children with clinically suspected LCP disease and negative/equivocal radiographs. All pediatric contrast-enhanced MRI examinations of the pelvis and hips performed between January 2000 and February 2009 to evaluate for possible LCP disease in the setting of negative/equivocal radiographs were identified. MRI examinations performed to evaluate for secondary avascular necrosis were excluded. Imaging reports were retrospectively reviewed for unexpected clinically important causes of hip pain. Thirty-six pediatric patients underwent contrast-enhanced MRI examinations for clinically suspected LCP disease in the setting of negative/equivocal radiographs. Twenty-two (61%) imaging studies were normal, while four (11%) imaging studies demonstrated findings consistent with LCP disease. Ten (28%) imaging studies revealed unexpected clinically important causes of hip pain, including nonspecific unilateral joint effusion and synovitis (n = 7, juvenile chronic arthritis was eventually diagnosed in 3 patients), sacral fracture (n = 1), apophyseal injury (n = 1), and femoral head subluxation (n = 1). MRI frequently reveals unexpected clinically important causes of hip pain in children with suspected LCP disease and negative/equivocal radiographs. (orig.)

  13. Neuroradiological findings in primary progressive aphasia: CT, MRI and cerebral perfusion SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Sinnatamby, R. [Dept. of Radiology, Addenbrooke`s Hospital NHS Trust, Cambridge (United Kingdom); Antoun, N.A. [Dept. of Radiology, Addenbrooke`s Hospital NHS Trust, Cambridge (United Kingdom); Freer, C.E.L. [Dept. of Radiology, Addenbrooke`s Hospital NHS Trust, Cambridge (United Kingdom); Miles, K.A. [Dept. of Nuclear Medicine, Addenbrooke`s Hospital NHS Trust, Cambridge (United Kingdom); Hodges, J.R. [Dept. of Neurology, Addenbrooke`s Hospital NHS Trust, Cambridge (United Kingdom)

    1996-04-01

    Primary progressive aphasia (PPA) is defined as progressive decline in language for 2 or more years with preservation of activities of daily living and general cognitive functions. Whereas the clinical features of this syndrome have been well documented, the neuroradiological findings have not been studied systematically. We studied 13 patients with PPA retrospectively: 10 underwent CT, 12 MRI and 12 cerebral perfusion studies using {sup 99m}Tc-HMPAO SPECT. CT and MR images were scored for focal atrophy by two independent assessors. Initial qualitative assessment of SPECT images was confirmed by quantitative analysis. CY was normal in 5 patients. Focal atrophy, affecting predominantly the left temporal lobe, was seen in 4 of 10 patients on CT, and 10 of 12 on MRI. Atrophy was localised primarily to the superior and middle temporal gyri on MRI. All 12 patients who underwent SPECT had unilateral temporal lobe perfusion defects, in 2 patients of whom MRI was normal. CT is relatively insensitive to focal abnormalities in PPA; MRI and SPECT are the imaging modalities of choice. MRI allows accurate, specific localisation of atrophy with the temporal neocortex. SPECT may reveal a functional decrease in cerebral perfusion prior to establishment of structural change. (orig.)

  14. Incidental findings at MRI-enterography in patients with suspected or known Crohn’s disease

    OpenAIRE

    Michael Dam Jensen, Torben Nathan, Jens Kjeldsen, Søren Rafael Rafaelsen

    2010-01-01

    AIM: To determine the frequency and clinical impact of incidental findings detected with magnetic resonance imaging (MRI)-enterography in patients with suspected or known Crohn’s disease (CD).METHODS: Incidental findings were defined as unexpected lesions outside the small intestine, not previously known or suspected at the time of referral, and not related to inflammatory bowel disease. Through a systematic review of medical charts we analyzed the clinical impact of incidental findings, and ...

  15. Cine magnetic resonance

    International Nuclear Information System (INIS)

    Cine magnetic resonance (MR) is a fast MR imaging process with referencing of the imaging data to the electrocardiogram (ECG) so that images corresponding to 21-msec segments of the cardiac cycle are acquired. A series of such images, each corresponding to a 21-msec segment of the cardiac cycle, can be laced together for viewing in the cine format at a framing rate of 20 to 40 frames per second. Since cine angiograms of the heart are usually done at 30 frames per second, this technique achieves a temporal resolution adequate for the evluation of central cardiovascular function. The major application of this technique is to depict central cardiovascular function and blood flow

  16. Evaluation of Agreement between CT scan and MRI Findings of 96 Pathologically Proved Gliomas

    Directory of Open Access Journals (Sweden)

    M. Sanei Taheri

    2008-01-01

    Full Text Available Background/Objective: The aim of this study was to report the main CT scan and MRI findings of gliomas in a group of Iranian patients and also to assess the agreement between these imaging findings."nPatients and Methods: The MRI and CT scan of 96 pathologically proven cases of gliomas were retro-spectively evaluated in a period of five years in our university-affiliated hospital. We entered all cases, which had both CT scan and MRI in our study. Both CT scan and MRIs reported by one radiologist who was blinded for pathological findings. We evaluated agreement between CT scan and MRI for all cases and also for astrocytoma, glioblastoma multiform, and other gliomas separately. "nResults: Among our patients, 60 (62.5% were male and 36 (37.5% were female. The mean age of our cases was 41.8±19.3 (7-78.The most common loca-tion was in the parietal lobes (54.2% followed by the temporal lobes (52.1%, and the frontal lobes (39.6%. The most common subtype was glioblastoma multi-form in 42 patients (43.8%.There was an excellent agreement for mass effect, ventricular effect, cystic formation, and midline shift in all gliomas (all Kap-pas> 0.8; all P<0.002. We found good correlation be-tween CT scan and MRI for hemorrhage, edema, en-hancement, and enhancement severity in our pa-tients. (all Kappas> 0.6; all P<0.0001."nConclusion: In contrast with many other studies, the most common site of gliomas in our patients was pa-rietal lobes. Except for calcification, we found accept-able correlation between CT scan and MRI findings of gliomas.

  17. MRI findings of pancreatic lymphoma and autoimmune pancreatitis: A comparative study

    Energy Technology Data Exchange (ETDEWEB)

    Ishigami, Kousei, E-mail: Ishigamikousei@aol.co [Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582 (Japan); Tajima, Tsuyoshi; Nishie, Akihiro; Ushijima, Yasuhiro [Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582 (Japan); Fujita, Nobuhiro [Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University (Japan); Asayama, Yoshiki; Kakihara, Daisuke; Irie, Hiroyuki [Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582 (Japan); Ito, Tetsuhide; Igarashi, Hisato [Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University (Japan); Nakamura, Masafumi [Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University (Japan); Honda, Hiroshi [Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582 (Japan)

    2010-06-15

    Purpose: To clarify whether there are differences in MRI findings between pancreatic lymphomas and autoimmune pancreatitis (AIP). Materials and methods: MRI of 8 patients with pancreatic lymphomas and 21 patients with AIP were retrospectively reviewed. For multifocal pancreatic lymphomas (n = 2) and AIP (n = 4), the largest 2 lesions were evaluated. Ten pancreatic lymphomas and 25 AIP were compared on three bases: the signal intensity on T2-weighted images, internal homogeneity, and presence or absence of capsule-like rim. In 8 lymphomas and 19 AIP, the enhancement pattern on dynamic MRI was compared, as well. Results: On T2-weighted images, pancreatic lymphomas comprised 5, 5 and 4 lesions with low (iso), slightly high, and moderately high intensity, respectively, while the numbers for AIP were 14, 10, and 1 (P < 0.01). Nine of 10 (90%) lymphomas appeared homogenous, and 11 of 25 (44%) AIP were homogenous (P < 0.05). A capsule-like rim was present in 9 of 25 (36%) AIP, but was not seen in lymphomas (P < 0.05). On dynamic MRI, 18 of 19 (94.7%) AIP showed persistent (n = 5) or delayed enhancement (n = 13), and 6 of 8 (75%) lymphomas showed low intensity without delayed enhancement (P < 0.001). Conclusion: MRI findings for pancreatic lymphomas and AIP were significantly different, which may be helpful for the differential diagnosis of these two diseases.

  18. Inflammatory myofibroblastic tumour of the maxillary sinus: CT and MRI findings

    International Nuclear Information System (INIS)

    Aim: To characterize the computed tomography (CT) and magnetic resonance imaging (MRI) findings of inflammatory myofibroblastic tumours (IMTs) of the maxillary sinus. Materials and methods: The imaging findings of eight patients with IMTs of the maxillary sinus were reviewed retrospectively. Of the eight patients, four patients underwent unenhanced and contrast-enhanced CT, and one patient underwent unenhanced CT only; three patients underwent unenhanced and contrast-enhanced MRI. Results: Five cases of IMTs occurred in the left maxillary sinus, while three cases were right-sided. Four cases occupied the entire sinus, and the other four cases only partially occupied the sinus. Unenhanced CT images showed heterogeneous masses in four cases and a homogeneous mass in one case. One of the tumours showed some areas of calcification. T1-weighted MRI images showed isointense lesions. T2-weighted images showed mixed isointense and mild hyperintense lesions. All cases showed bone destruction and had infiltrated into the nasal fossa, orbit, infratemporal fossa, and other adjacent tissues. Seven cases showed mild to moderate heterogeneous enhancement on contrast-enhanced CT or T1-weighted MRI images. Conclusion: IMTs of the maxillary sinus can be characterized as a soft-tissue mass with bony destruction and infiltration of the adjacent tissues, with mild to moderate enhancement after the injection of contrast medium. CT and MRI can help to diagnose IMTs, determine the extent of the lesion and its relationship with adjacent tissues, and thus facilitate the prediction of surgical resectability.

  19. Localized hypertrophic neuropathy of the sciatic nerve in children: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Roux, Adrien; Treguier, Catherine; Bruneau, Bertrand; Marin, Franck; Gandon, Yves; Gauvrit, Jean-Yves [University Hospital, Department of Radiology, Hopital Sud, 16 Boulevard de Bulgarie, BP 90347, Rennes cedex 2 (France); Riffaud, Laurent [University Hospital, Department of Pediatric Neurosurgery, Hopital Sud, Rennes (France); Violas, Philippe [University Hospital, Department of Pediatric Surgery, Hopital Sud, Rennes (France); Michel, Anne [University Hospital, Department of Neurological Functional Explorations, Hopital Sud, Rennes (France)

    2012-08-15

    Localized hypertrophic neuropathy (LHN) of the sciatic nerve in children is a rare condition characterized by a painless neurological deficit in the sciatic nerve territory. To demonstrate the role of MRI using a specific protocol and describe the primary findings in LHN. Imaging in four children (age 2 years to 12 years) is presented. All children presented with lower limb asymmetry. Three had a steppage gait. LHN was confirmed by electrophysiological studies and by MRI of the whole sciatic nerve with a dedicated protocol covering the lumbar spine and the lower limb. There were four direct MRI findings: (1) linear and focal hypertrophy with progressive enlargement of a peripheral nerve or plexus diameter, (2) abnormal hyperintensity of the nerve on T2-weighted images, (3) preserved fascicular configuration, and (4) variable enhancement after intravenous gadolinium administration. In addition there were atrophy and fatty infiltration of innervated muscles. MRI was helpful for determining the extent of lesions and in excluding peripheral nerve compression or tumour. MRI of the whole sciatic nerve is the method of choice for diagnosing LHN of the sciatic nerve. (orig.)

  20. MRI findings of inflammatory myofibroblastic tumor of the soft tissue

    International Nuclear Information System (INIS)

    Objective: To describe MR findings in inflammatory myofibroblastic tumor (IMT) of the soft tissue. Methods: MR manifestations of 11 cases of IMT of the soft tissue were retrospectively analyzed, and the MR findings were correlated with surgical and histological results. Results: The pathological classification of the tumors was type I in 1 case, type II in 4 cases, mainly type II admixed with type I in 3 cases, and mainly type II admixed with type III in 3 eases. In 4 cases with primary tumor, the tumors were spheroid in shape, with well-defined margin and pseudocapsule. In 2 eases with primary axillary tumor and 5 cases with recurrent tumor, the tumors were irregular in shape, with ill-defined margin and invasion of adjacent structures. The tumors were mainly isointensive in T1-weighted images. Tumors of different pathological classifications had different signal intensities in T2-weighted images: 1 case of type I tumor was bright; 4 cases of type II tumor and 3 cases of type II tumor admixed with type I tumor were slightly bright; 3 cases of type II tumor admixed with type III were isointense or slightly hypointense in signal. All of the 11 cases in the study exhibited 'pitaya cross-section sign' in T2-weighted sequence, which referred to discrete punctuate foci of relatively hypointensity in the background of hyperintensity, slightly hypointensity or isointensity. All of the 11 cases exhibited inhomogeneously significant enhancement after gadolinium administration. In the follow-up of the 6 eases of primary tumor, 4 cases had recurrence, 1 case had no recurrence, and 1 case was lost in the follow-up process. In the follow-up of the 5 cases of recurrent tumor, 4 cases showed recurrence again, and 3 cases were lost in the follow-up process. Conclusions: The IMT of the soft tissue has characteristic MR features. The signal intensity of the tumor on T2-weighted sequence could reflect the pathological type of the tumor' to some extent. 'pitaya cross-section sign' could be a pathogenomic sign of the IMT of the soft tissue. (authors)

  1. Clinical, MRI and perfusion SPECT findings in strategic infarct dementia

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Do Young; Park, Kyung Won; Cha, Jae Kwan; Kim, Sang Ho; Kim, Jae Woo [Dong-A University College of Medicine, Busan (Korea, Republic of)

    2002-07-01

    Strategic infarct dementia (SID) is characterized by focal ischemic lesions involving specific sites that are critical for higher cortical functions. The mechanism of SID are not well understood. We evaluate lesion sites, neuropsychiatric symptoms, brain perfusion SPECT and neuropsychological findings in patients with SID. Eleven patients with SID according to NINDS-AIREN criteria for vascular dementia were included. All patients performed brain MR and MRA, Tc-99m HMPAO brain perfusion SPECT. Various sites were responsible for SID; thalamus(n=3), medial temporal lobe(n=3), medial frontal lobe(n=1), genu of internal capsule(n=1), caudate nucleus(n=1), angular gyrus(n=1) and temporooccipital lobe(n=1). The most common neuropsychiatric symptoms were apathy and indifference by K-NPI. Brain perfusion SPECT revealed ipsilateral cortical hypoperfusion, mainly in frontal and temporal lobe area, in patients with subcortical strategic infarct. On neuropsychological assessment, cognitive deficits on attention and frontal executive function were prominent. The thalamus and medial temporal lobe were the most common sites responsible for SID. It was suggested that strategic disruption of frontal-subcortical circuit be an important role to produce SID in patients with subcortical strategic lesions.

  2. Clinical, MRI and perfusion SPECT findings in strategic infarct dementia

    International Nuclear Information System (INIS)

    Strategic infarct dementia (SID) is characterized by focal ischemic lesions involving specific sites that are critical for higher cortical functions. The mechanism of SID are not well understood. We evaluate lesion sites, neuropsychiatric symptoms, brain perfusion SPECT and neuropsychological findings in patients with SID. Eleven patients with SID according to NINDS-AIREN criteria for vascular dementia were included. All patients performed brain MR and MRA, Tc-99m HMPAO brain perfusion SPECT. Various sites were responsible for SID; thalamus(n=3), medial temporal lobe(n=3), medial frontal lobe(n=1), genu of internal capsule(n=1), caudate nucleus(n=1), angular gyrus(n=1) and temporooccipital lobe(n=1). The most common neuropsychiatric symptoms were apathy and indifference by K-NPI. Brain perfusion SPECT revealed ipsilateral cortical hypoperfusion, mainly in frontal and temporal lobe area, in patients with subcortical strategic infarct. On neuropsychological assessment, cognitive deficits on attention and frontal executive function were prominent. The thalamus and medial temporal lobe were the most common sites responsible for SID. It was suggested that strategic disruption of frontal-subcortical circuit be an important role to produce SID in patients with subcortical strategic lesions

  3. Brain MRI findings in two cases with eclampsia

    Energy Technology Data Exchange (ETDEWEB)

    Uenal, Mustafa; Senakayli, Oe Cem; Serce, Kemal [Karadeniz Technical Univ., Trabzon, (Turkey). Dept. of Radiology

    1996-08-01

    Neurological complications in patients with eclampsia are varied and include headache, visual disturbances, focal neurological deficits, altered mental status and coma. Occasionally, a focal neurological deficit includes a variety of visual disturbances. The pathophysiology of CNS abnormalities in patients with eclampsia is uncertain. Our cases, combined with a review of the literature, demonstrate that there is no correlation among severity of hypertension, parity, and location of lesions at initial magnetic resonance (MR) imaging findings or between the severity of hypertension and neurological symptoms. Two typical patterns are seen on MR images of patients with eclampsia. Lesions in the region of the posterior cerebral circulation are most common and are frequently associated with visual disturbances. Although there are lesions in the deep white matter or basal ganglia, a focal neurological deficit or alterations in mental status may not develop. This demonstrates the sensitivity of MR imaging in the detection of abnormalities in patients with eclampsia, even those without neurological deficits. 13 refs., 1 tab., 2 figs.

  4. Brain MRI findings in two cases with eclampsia

    International Nuclear Information System (INIS)

    Neurological complications in patients with eclampsia are varied and include headache, visual disturbances, focal neurological deficits, altered mental status and coma. Occasionally, a focal neurological deficit includes a variety of visual disturbances. The pathophysiology of CNS abnormalities in patients with eclampsia is uncertain. Our cases, combined with a review of the literature, demonstrate that there is no correlation among severity of hypertension, parity, and location of lesions at initial magnetic resonance (MR) imaging findings or between the severity of hypertension and neurological symptoms. Two typical patterns are seen on MR images of patients with eclampsia. Lesions in the region of the posterior cerebral circulation are most common and are frequently associated with visual disturbances. Although there are lesions in the deep white matter or basal ganglia, a focal neurological deficit or alterations in mental status may not develop. This demonstrates the sensitivity of MR imaging in the detection of abnormalities in patients with eclampsia, even those without neurological deficits. 13 refs., 1 tab., 2 figs

  5. MRI findings on iatrogenic spinal infection following various pain management procedures

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yu Jin; Lee, Jee Young; Kim, Bong Man [Dept. of Radiology, Dankook University Hospital, Cheonan (Korea, Republic of); Min, Sang Hyuk [Dept. of Orthopedic Surgery, Dankook University Hospital, Cheonan (Korea, Republic of)

    2014-12-15

    The aim of this study was to investigate and report magnetic resonance imaging (MRI) findings of iatrogenic spinal infection (ISI). We retrospectively reviewed the clinical and MRI findings on 18 patients diagnosed with ISI. The MRI findings were evaluated for the number of spinal segments showing inflammation in the longitudinal span and affected vertebral bodies and discs, the presence of abscess in the epidural or paravertebral space, paravertebral myositis, and skip lesions. Among the 18 patients, the range of the longitudinal span of spinal inflammation was 2-11 (mean = 5.84) vertebral segments. 17 of the 18 patients had three or more contiguous vertebral segments. The osteomyelitis and disc destruction was apparent in 77.8% and 66.7% of the patients, and 78% of patients with osteomyelitis showed involvement of one or two vertebrae; 91.7% of patients with disc destruction showed involvement of single disc. The incidence of epidural or paravertebral abscesses, and paravertebral myositis were 88.9%, and 94.4%. There were no spinal skip lesions. MRI findings of those are wide longitudinal span of infection, involvement of no more than one or two vertebral bodies and a single disc, large abscesses, extensive myositis and no skip lesions, can be a useful ISI-diagnostic tool.

  6. MRI findings on iatrogenic spinal infection following various pain management procedures

    International Nuclear Information System (INIS)

    The aim of this study was to investigate and report magnetic resonance imaging (MRI) findings of iatrogenic spinal infection (ISI). We retrospectively reviewed the clinical and MRI findings on 18 patients diagnosed with ISI. The MRI findings were evaluated for the number of spinal segments showing inflammation in the longitudinal span and affected vertebral bodies and discs, the presence of abscess in the epidural or paravertebral space, paravertebral myositis, and skip lesions. Among the 18 patients, the range of the longitudinal span of spinal inflammation was 2-11 (mean = 5.84) vertebral segments. 17 of the 18 patients had three or more contiguous vertebral segments. The osteomyelitis and disc destruction was apparent in 77.8% and 66.7% of the patients, and 78% of patients with osteomyelitis showed involvement of one or two vertebrae; 91.7% of patients with disc destruction showed involvement of single disc. The incidence of epidural or paravertebral abscesses, and paravertebral myositis were 88.9%, and 94.4%. There were no spinal skip lesions. MRI findings of those are wide longitudinal span of infection, involvement of no more than one or two vertebral bodies and a single disc, large abscesses, extensive myositis and no skip lesions, can be a useful ISI-diagnostic tool.

  7. Intra-articular nodular fasciitis of the knee: A case report of MRI findings

    International Nuclear Information System (INIS)

    Nodular fasciitis, a benign soft tissue tumor consisting of myofibroblastic proliferation, is commonly located in the subcutaneous or inter- or intra-muscular layer of extremites. Intra-articular nodular fasciitis is extremely rare. We report a case of MRI findings of a nodular fasciitis in the knee of a 13-year-old boy which was removed by arthroscopic surgery and pathologically confirmed.

  8. Intra-articular nodular fasciitis of the knee: A case report of MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, O Hyun; Cho, Kil Ho; Suh, Jang Ho; Choi, Joon Hyuk [Yeungnam University College of Medicine, Daegu (Korea, Republic of)

    2014-11-15

    Nodular fasciitis, a benign soft tissue tumor consisting of myofibroblastic proliferation, is commonly located in the subcutaneous or inter- or intra-muscular layer of extremites. Intra-articular nodular fasciitis is extremely rare. We report a case of MRI findings of a nodular fasciitis in the knee of a 13-year-old boy which was removed by arthroscopic surgery and pathologically confirmed.

  9. Whole-heart cine MRI in a single breath-hold. A compressed sensing accelerated 3D acquisition technique for assessment of cardiac function

    International Nuclear Information System (INIS)

    Purpose: The aim of this study was to perform functional MR imaging of the whole heart in a single breath-hold using an undersampled 3 D trajectory for data acquisition in combination with compressed sensing for image reconstruction. Materials and Methods: Measurements were performed using an SSFP sequence on a 3 T whole-body system equipped with a 32-channel body array coil. A 3 D radial stack-of-stars sampling scheme was utilized enabling efficient undersampling of the k-space and thereby accelerating data acquisition. Compressed sensing was applied for the reconstruction of the missing data. A validation study was performed based on a fully sampled dataset acquired by standard Cartesian cine imaging of 2 D slices on a healthy volunteer. The results were investigated with regard to systematic errors and resolution losses possibly introduced by the developed reconstruction. Subsequently, the proposed technique was applied for in-vivo functional cardiac imaging of the whole heart in a single breath-hold of 27 s. The developed technique was tested on three healthy volunteers to examine its reproducibility. Results: By means of the results of the simulation (temporal resolution: 47 ms, spatial resolution: 1.4 x 1.4 x 8 mm, 3 D image matrix: 208 x 208 x 10), an overall acceleration factor of 10 has been found where the compressed sensing reconstructed image series shows only very low systematic errors and a slight in-plane resolution loss of 15 %. The results of the in-vivo study (temporal resolution: 40.5 ms, spatial resolution: 2.1 x 2.1 x 8 mm, 3 D image matrix: 224 x 224 x 12) performed with an acceleration factor of 10.7 confirm the overall good image quality of the presented technique for undersampled acquisitions. Conclusion: The combination of 3 D radial data acquisition and model-based compressed sensing reconstruction allows high acceleration factors enabling cardiac functional imaging of the whole heart within only one breath-hold. The image quality in the simulated dataset and the in-vivo measurement highlights the great potential of the presented technique for an efficient assessment of cardiac functional parameters. (orig.)

  10. Whole-heart cine MRI in a single breath-hold. A compressed sensing accelerated 3D acquisition technique for assessment of cardiac function

    Energy Technology Data Exchange (ETDEWEB)

    Wech, T.; Koestler, H. [Wuerzburg Univ. (Germany). Inst. of Radiology; Wuerzburg Univ. (Germany). Comprehensive Heart Failure Center; Pickl, W.; Tran-Gia, J.; Ritter, C.; Hahn, D. [Wuerzburg Univ. (Germany). Inst. of Radiology; Beer, M. [Wuerzburg Univ. (Germany). Inst. of Radiology; Graz Univ. (Austria). University Hospital Radiology

    2014-01-15

    Purpose: The aim of this study was to perform functional MR imaging of the whole heart in a single breath-hold using an undersampled 3 D trajectory for data acquisition in combination with compressed sensing for image reconstruction. Materials and Methods: Measurements were performed using an SSFP sequence on a 3 T whole-body system equipped with a 32-channel body array coil. A 3 D radial stack-of-stars sampling scheme was utilized enabling efficient undersampling of the k-space and thereby accelerating data acquisition. Compressed sensing was applied for the reconstruction of the missing data. A validation study was performed based on a fully sampled dataset acquired by standard Cartesian cine imaging of 2 D slices on a healthy volunteer. The results were investigated with regard to systematic errors and resolution losses possibly introduced by the developed reconstruction. Subsequently, the proposed technique was applied for in-vivo functional cardiac imaging of the whole heart in a single breath-hold of 27 s. The developed technique was tested on three healthy volunteers to examine its reproducibility. Results: By means of the results of the simulation (temporal resolution: 47 ms, spatial resolution: 1.4 x 1.4 x 8 mm, 3 D image matrix: 208 x 208 x 10), an overall acceleration factor of 10 has been found where the compressed sensing reconstructed image series shows only very low systematic errors and a slight in-plane resolution loss of 15 %. The results of the in-vivo study (temporal resolution: 40.5 ms, spatial resolution: 2.1 x 2.1 x 8 mm, 3 D image matrix: 224 x 224 x 12) performed with an acceleration factor of 10.7 confirm the overall good image quality of the presented technique for undersampled acquisitions. Conclusion: The combination of 3 D radial data acquisition and model-based compressed sensing reconstruction allows high acceleration factors enabling cardiac functional imaging of the whole heart within only one breath-hold. The image quality in the simulated dataset and the in-vivo measurement highlights the great potential of the presented technique for an efficient assessment of cardiac functional parameters. (orig.)

  11. Lumbar Modic Changes - A Comparison Between Findings at Low-and High-field MRI

    DEFF Research Database (Denmark)

    Bendix, Tom; Sorensen, Joan S; Henriksson, Gustaf A C; Bolstad, Jørn Espen; Narvestad, Eva K; Jensen, Tue Secher

    2012-01-01

    Study Design. A cross-sectional observational study.Objective. To investigate if there is a difference in findings of lumbar Modic changes in low-field (0.3 Tesla) magnetic resonance imaging (MRI) as compared to high field (1.5 Tesla).Summary of Background Data. It is a challenge to give patients with low back pain (LBP) a specific diagnosis. Modic changes as seen on MRI have been reported to be a possible source of pain. However, it is unclear if the diagnosis is independent on the field streng...

  12. Wernicke’s Encephalopathy Following Gastrointestinal Surgery; MRI and DWI Findings

    Directory of Open Access Journals (Sweden)

    Betül K?z?lda?

    2014-09-01

    Full Text Available Wernicke’s encephalopathy (WE is a neurologic disorder resulting from thiamine (vitamin B1 deficiency and characterised by the ocular signs, altered consciousness, and ataxia. It is usually associated with chronic alcohol abuse. Recently, it could be a complication of bariatric surgery. The classical clinical triad occurs in a small group of patients, and early replacement of thiamine is an important prognostic factor. Hence, a magnetic resonance imaging (MRI is useful to support the diagnosis. In this case, we report MRI and diffusion weighted imaging findings of WE in a patient without history of alcoholism after gastrointestinal surgery.

  13. Tuberculous adenitis: comparison of CT and MRI findings with histopathological features

    Energy Technology Data Exchange (ETDEWEB)

    Backer, A.I. de [General Hospital Sint-Lucas, Department of Radiology, Ghent (Belgium); Mortele, K.J. [Harvard Medical School, Department of Radiology, Division of Abdominal Imaging and Intervention, Brigham and Women' s Hospital, Boston, MA (United States); Heuvel, E. van den [University Hospital of Antwerp, Department of Pathology, Edegem (Belgium); Vanschoubroeck, I.J. [Ziekenhuisnetwerk Antwerpen, Stuivenberg, Department of Internal Medicine, Antwerp (Belgium); Kockx, M.M. [Ziekenhuisnetwerk Antwerpen, Stuivenberg, Department of Pathology, Antwerp (Belgium); Vyvere, M. van de [Ziekenhuisnetwerk Antwerpen, Stuivenberg, Department of Microbiology, Antwerp (Belgium)

    2007-04-15

    Our aim was to investigate the relationship between the various histopathological features and the CT and MRI findings in routinely submitted histopathological specimens for the diagnosis of tuberculous lymphadenopathy. Twelve formalin-fixed, paraffin-embedded tissue blocks from ten patients who were clinically suspected of having tuberculous lymphadenopathy were evaluated. We assessed the presence of histopathological features including granuloma formation, caseous necrosis, and presence of Langhans-type giant cells, calcifications, fibrosis or normal lymphoid tissue. We performed polymerase chain reaction (PCR)-based assay for mycobacterial DNA and Ziehl-Neelsen staining for acid-fast bacilli (AFB). Findings were compared with those of CT and MRI, including signal intensities on unenhanced MR images, lymph node homogeneity, attenuation values on contrast-enhanced CT and enhancement patterns on MRI. Based on CT and MRI findings, four lymph node types could be defined: (1) homogeneous nodes, visible on both pre- and post-contrast images and corresponding histopathologically to granulation tissue without or with minimal caseation necrosis (n = 2); (2) heterogeneous nodes, showing heterogeneous enhancement patterns with central non-enhancing areas and corresponding to minor or moderate intranodal caseation/liquefaction necrosis (n = 3); (3) nodes showing peripheral rim enhancement and corresponding to moderate or extensive intranodal caseation/liquefaction necrosis (n = 5); (4) heterogeneous nodes showing intranodal hyperdensities on CT and hypointense areas on T1- and T2-weighted images and corresponding to fibrosis and calcifications (n = 2). On CT and MRI, the findings reflect different stages of the tuberculous process. Imaging findings depend on the presence and the degree of granuloma formation, caseation/liquefaction necrosis, fibrosis and calcifications. (orig.)

  14. Tuberculous adenitis: comparison of CT and MRI findings with histopathological features

    International Nuclear Information System (INIS)

    Our aim was to investigate the relationship between the various histopathological features and the CT and MRI findings in routinely submitted histopathological specimens for the diagnosis of tuberculous lymphadenopathy. Twelve formalin-fixed, paraffin-embedded tissue blocks from ten patients who were clinically suspected of having tuberculous lymphadenopathy were evaluated. We assessed the presence of histopathological features including granuloma formation, caseous necrosis, and presence of Langhans-type giant cells, calcifications, fibrosis or normal lymphoid tissue. We performed polymerase chain reaction (PCR)-based assay for mycobacterial DNA and Ziehl-Neelsen staining for acid-fast bacilli (AFB). Findings were compared with those of CT and MRI, including signal intensities on unenhanced MR images, lymph node homogeneity, attenuation values on contrast-enhanced CT and enhancement patterns on MRI. Based on CT and MRI findings, four lymph node types could be defined: (1) homogeneous nodes, visible on both pre- and post-contrast images and corresponding histopathologically to granulation tissue without or with minimal caseation necrosis (n = 2); (2) heterogeneous nodes, showing heterogeneous enhancement patterns with central non-enhancing areas and corresponding to minor or moderate intranodal caseation/liquefaction necrosis (n = 3); (3) nodes showing peripheral rim enhancement and corresponding to moderate or extensive intranodal caseation/liquefaction necrosis (n = 5); (4) heterogeneous nodes showing intranodal hyperdensities on CT and hypointense areas on T1- and T2-weighted images and corresponding to fibrosis and calcifications (n = 2). On CT and MRI, the findings reflect different stages of the tuberculous process. Imaging findings depend on the presence and the degree of granuloma formation, caseation/liquefaction necrosis, fibrosis and calcifications. (orig.)

  15. Incidental findings in brain MRI research: what do we owe our subjects?

    Science.gov (United States)

    Borra, Ronald J H; Sorensen, A Gregory

    2011-12-01

    Concern regarding incidental findings on brain MRI studies has been increasing with the growing use of MRI as tool for scientific investigation. In this article, the authors provide an overview of possible approaches to address incidental findings. Incidental findings are surprisingly common (5%-20% of all examinations), although the percentage of clinically serious abnormalities is low (0.3%-3.4%). At present, there is no consensus concerning the optimal strategy on how to deal with incidental findings, in particular how to fulfill ethical responsibilities appropriately within the constraints of available resources. There are a variety of responses possible, and currently, reasonable guidelines exist for formulating a plan tailored to the needs of each institution that will meet the reasonable expectations of subjects participating in brain research studies. PMID:22137002

  16. MRI findings in 6 cases of children by inadvertent ingestion of diphenoxylate-atropine

    International Nuclear Information System (INIS)

    Purpose: Compound diphenoxylate (diphenoxylate-atropine) poisoning can cause toxic encephalopathy in children, and magnetic resonance imaging (MRI) of the brain in this condition has not been reported. This study is to analyze brain MRI findings and to investigate the relations between MRI features and possible pathophysiological changes in children. Methods: Six children accidentally swallowed compound diphenoxylate, 4 males, 2 females, aged 20-46 months, average 33 months. Quantity of ingested diphenoxylate-atropine was from 6 to 30 tablets, each tablet contains diphenoxylate 2.5 mg and atropine 0.025 mg. These patients were referred to our hospital within 24 h after diphenoxylate-atropine ingestion, and underwent brain MRI scan within 24-72 h after emergency treatment. The characteristics of conventional MRI were analyzed. Results: These pediatric patients had various symptoms of opioid intoxication and atropine toxicity. Brain MRI showed abnormal low signal intensity on T1-weighted images (T1WI) and abnormal high signal intensity on T2-weighted images (T2WI) and fluid-attenuated inversion recovery (FLAIR) imaging in bilateral in all cases; abnormal high signal intensity on T1WI, T2WI and FLAIR in 4 cases. Encephalomalacia was observed in 3 cases during follow-up. Conclusion: In the early stage of compound diphenoxylate poisoning in children, multiple extensive edema-necrosis and hemorrhagic-necrosis focus were observed in basic nucleus, pallium and cerebellum, these resulted in the corresponding brain dysfunction with encephalomalacia. MRI scan in the early stage in this condition may provide evidences of brain impairment, and is beneficial for the early diagnosis, treatment and prognosis assessment.

  17. Correlation between MRI and double-balloon urethrography findings in the diagnosis of female periurethral lesions

    International Nuclear Information System (INIS)

    This study aims to evaluate the correlation of MRI findings with double-balloon urethrography (DBU) in diagnosing female urethral diverticula and other periurethral lesions. In this retrospective study, females with clinically suspected periurethral lesions who underwent both MRI and DBU between 2008 and 2012 were evaluated. MRI was performed on a 1.5 Tesla unit using a pelvic phased array coil. Protocol included small FOV pelvic images, multiplanar T2-w, T1-w with and without contrast injection. DBU was performed by a dedicated catheter. Images were evaluated in consensus by two readers. Diverticula were evaluated by, size, number, complexity, location and connection to urethra, and other periurethral lesions were evaluated by size, location and connection. Supplement clinical and surgical data were retrieved from medical records and telephone interviews. Seventeen females (mean age 44 years, range 20–69) were included in the study. Diverticula were diagnosed by both modalities (9 cases), by neither (6 cases, 88% correlation) by MRI alone (1 case) and by DBU alone (1 case). Among diverticula, correlation of number, complexity, location and demonstration of connection to urethra was 89%, 67%, 67%, and 56%, respectively. Alternative diagnosis solely by MRI included vaginal wall cysts (3 cases), endometriosis (1 case) and ectopic ureter (1 case). No periurethral lesion was found by either modality in 2 cases. The correlation between MRI and DBU in diagnosing female periurethral lesions is very good for anatomical delineation of diverticula. MRI, which does not involve radiation, may also indicate alternative diagnoses that can contribute to proper patient management

  18. Correlation between MRI and double-balloon urethrography findings in the diagnosis of female periurethral lesions

    Energy Technology Data Exchange (ETDEWEB)

    Portnoy, Orith, E-mail: Orith.Portnoy@sheba.health.gov.il [Department of Diagnostic Imaging, Sheba Medical Center, Tel Hasomer, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Kitrey, Noam, E-mail: nkitrey@gmail.com [Department of Urology, Sheba Medical Center, Tel Hasomer, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Eshed, Iris, E-mail: iris.eshed@sheba.health.gov.il [Department of Diagnostic Imaging, Sheba Medical Center, Tel Hasomer, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Apter, Sara, E-mail: saraapter@gmail.com [Department of Diagnostic Imaging, Sheba Medical Center, Tel Hasomer, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Amitai, Marianne M., E-mail: michal.amitai@sheba.health.gov.il [Department of Diagnostic Imaging, Sheba Medical Center, Tel Hasomer, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Golomb, Jacob, E-mail: Jacob.golomb@yahoo.com [Department of Urology, Sheba Medical Center, Tel Hasomer, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel)

    2013-12-01

    This study aims to evaluate the correlation of MRI findings with double-balloon urethrography (DBU) in diagnosing female urethral diverticula and other periurethral lesions. In this retrospective study, females with clinically suspected periurethral lesions who underwent both MRI and DBU between 2008 and 2012 were evaluated. MRI was performed on a 1.5 Tesla unit using a pelvic phased array coil. Protocol included small FOV pelvic images, multiplanar T2-w, T1-w with and without contrast injection. DBU was performed by a dedicated catheter. Images were evaluated in consensus by two readers. Diverticula were evaluated by, size, number, complexity, location and connection to urethra, and other periurethral lesions were evaluated by size, location and connection. Supplement clinical and surgical data were retrieved from medical records and telephone interviews. Seventeen females (mean age 44 years, range 20–69) were included in the study. Diverticula were diagnosed by both modalities (9 cases), by neither (6 cases, 88% correlation) by MRI alone (1 case) and by DBU alone (1 case). Among diverticula, correlation of number, complexity, location and demonstration of connection to urethra was 89%, 67%, 67%, and 56%, respectively. Alternative diagnosis solely by MRI included vaginal wall cysts (3 cases), endometriosis (1 case) and ectopic ureter (1 case). No periurethral lesion was found by either modality in 2 cases. The correlation between MRI and DBU in diagnosing female periurethral lesions is very good for anatomical delineation of diverticula. MRI, which does not involve radiation, may also indicate alternative diagnoses that can contribute to proper patient management.

  19. MRI findings in 6 cases of children by inadvertent ingestion of diphenoxylate-atropine

    Energy Technology Data Exchange (ETDEWEB)

    Xiao Lianxiang [Shandong University School of Medicine, Shandong Medical Imaging Research Institute , No. 44 West Wenhua Road, Jinan 250012 (China); Lin Xiangtao, E-mail: yishui1982@126.com [Shandong University School of Medicine, Shandong Medical Imaging Research Institute, No. 44 West Wenhua Road, Jinan 250012 (China); Cao Jinfeng [Shandong University School of Medicine, Shandong Medical Imaging Research Institute , No. 44 West Wenhua Road, Jinan 250012 (China); Wang Xueyu [Division of Pediatrics, Shandong Provincial Hospital, Shandong University, No. 324 Jingwu Road, Jinan 250021 (China); Wu Lebin [Shandong Medical Imaging Research Institute, No. 324 Jingwu Road, Jinan 250021 (China)

    2011-09-15

    Purpose: Compound diphenoxylate (diphenoxylate-atropine) poisoning can cause toxic encephalopathy in children, and magnetic resonance imaging (MRI) of the brain in this condition has not been reported. This study is to analyze brain MRI findings and to investigate the relations between MRI features and possible pathophysiological changes in children. Methods: Six children accidentally swallowed compound diphenoxylate, 4 males, 2 females, aged 20-46 months, average 33 months. Quantity of ingested diphenoxylate-atropine was from 6 to 30 tablets, each tablet contains diphenoxylate 2.5 mg and atropine 0.025 mg. These patients were referred to our hospital within 24 h after diphenoxylate-atropine ingestion, and underwent brain MRI scan within 24-72 h after emergency treatment. The characteristics of conventional MRI were analyzed. Results: These pediatric patients had various symptoms of opioid intoxication and atropine toxicity. Brain MRI showed abnormal low signal intensity on T1-weighted images (T1WI) and abnormal high signal intensity on T2-weighted images (T2WI) and fluid-attenuated inversion recovery (FLAIR) imaging in bilateral in all cases; abnormal high signal intensity on T1WI, T2WI and FLAIR in 4 cases. Encephalomalacia was observed in 3 cases during follow-up. Conclusion: In the early stage of compound diphenoxylate poisoning in children, multiple extensive edema-necrosis and hemorrhagic-necrosis focus were observed in basic nucleus, pallium and cerebellum, these resulted in the corresponding brain dysfunction with encephalomalacia. MRI scan in the early stage in this condition may provide evidences of brain impairment, and is beneficial for the early diagnosis, treatment and prognosis assessment.

  20. Brain MRI findings of welders : high signal intensity in T1WI secondary to manganese exposure

    Energy Technology Data Exchange (ETDEWEB)

    Kim, K. W.; Lim, M. A.; Shon, M. Y.; Lee, S. H.; Ha, D. G.; Kwon, K. R.; Kim, S. S.; Hong, Y. S.; Lee, Y. H. [Sunlin Presbyterian Hospital, Pohang (Korea, Republic of); Cheong, H. K. [Dongguk University, Seoul (Korea, Republic of)

    1998-03-01

    To evaluate the clinical and brain MRI findings of welders and to determine the utility of MRI in the assessment of occupational manganese exposure. All welders complained of fatigue, headache, anorexia, and decreased libido. The palmomental reflex was positive in five (28%), Myerson`s sign in four (22%), and intention tremor in three (17%). Mean blood Mn was 5.18 (range, 1.77-9.34) {mu}g/dl, mean urine Mn was 5.84 (range, 1.07 -22) {mu}g/l, serum Fe was elevated in one welder, and serum Cd in two. T1WI of brain MRI revealed high signal intensities in the globus pallidus, the putamen, the substantia nigra, the tectum, the caudate nucleus, the subthalamic nucleus, the hypothalamus and the pituitary gland. These intensities correlated closely with blood Mn levels, suggesting their potential role in estimating the accumulation of Mn in the brain. (author). 25 refs., 2 tabs., 5 figs.

  1. Cognitive function and MRI findings in very low birth weight infants

    International Nuclear Information System (INIS)

    Twenty-two very low birth weight infants at preschool ages of 5-6 years were studied to clarify the correlation between cognitive function and MRI findings. Cognitive function was evaluated by the Wechsler Intelligence Scale for Children-Revised (WISC-R) and the Frostig developmental test of visual perception. Ventricular enlargement, assessed by the bioccipital index (B.I.) measured on MRI, was correlated to cognitive disorders. Children with periventricular high intensity areas (T2-weighted images) extending from the posterior periventricular region to the parietal lobe tend to highly suffer from cerebral palsy and visuoperceptual impairment. These results indicate that the disorders of cognitive function in very low birth weight infants were caused by a damage of association fibers in periventricular areas which was detectable by MRI. (author)

  2. Brain MRI findings of welders : high signal intensity in T1WI secondary to manganese exposure

    International Nuclear Information System (INIS)

    To evaluate the clinical and brain MRI findings of welders and to determine the utility of MRI in the assessment of occupational manganese exposure. All welders complained of fatigue, headache, anorexia, and decreased libido. The palmomental reflex was positive in five (28%), Myerson's sign in four (22%), and intention tremor in three (17%). Mean blood Mn was 5.18 (range, 1.77-9.34) ?g/dl, mean urine Mn was 5.84 (range, 1.07 -22) ?g/l, serum Fe was elevated in one welder, and serum Cd in two. T1WI of brain MRI revealed high signal intensities in the globus pallidus, the putamen, the substantia nigra, the tectum, the caudate nucleus, the subthalamic nucleus, the hypothalamus and the pituitary gland. These intensities correlated closely with blood Mn levels, suggesting their potential role in estimating the accumulation of Mn in the brain. (author). 25 refs., 2 tabs., 5 figs

  3. Cognitive function and MRI findings in very low birth weight infants

    Energy Technology Data Exchange (ETDEWEB)

    Imamura, Atsuko; Takagishi, Yuka; Takada, Satoru; Uetani, Yoshiyuki; Nakamura, Toru; Nakamura, Hajime [Kobe Univ. (Japan). School of Medicine; Inagaki, Yuko

    1996-07-01

    Twenty-two very low birth weight infants at preschool ages of 5-6 years were studied to clarify the correlation between cognitive function and MRI findings. Cognitive function was evaluated by the Wechsler Intelligence Scale for Children-Revised (WISC-R) and the Frostig developmental test of visual perception. Ventricular enlargement, assessed by the bioccipital index (B.I.) measured on MRI, was correlated to cognitive disorders. Children with periventricular high intensity areas (T{sub 2}-weighted images) extending from the posterior periventricular region to the parietal lobe tend to highly suffer from cerebral palsy and visuoperceptual impairment. These results indicate that the disorders of cognitive function in very low birth weight infants were caused by a damage of association fibers in periventricular areas which was detectable by MRI. (author)

  4. Brain CT and MRI findings of a long-term case of subacute sclerosing panencephalitis

    International Nuclear Information System (INIS)

    Our study involved a long-term case (ten years) of subacute sclerosing panencephalitis. The case began with a 23 year-old experiencing visual deterioration. During the course of his illness, amnesia, autism and abnormal behavior were observed without any myoclonus. On the electroencephalogram, periodic synclonous discharge was shown in the early stage of his illness and subsequently disappeared. The brain CT and the MRI disclosed diffuse lesions in both cortical and subcortical areas of the cerebral hemispheres. The location and spread of lesions were more clearly revealed by the MRI than the brain CT. These findings suggest that the MRI is more useful than the brain CT in the diagnosis of subacute sclerosing panencephalitis. (author)

  5. MRI findings of intracranial meningioma: significance of Gd-DTPA enhancement

    International Nuclear Information System (INIS)

    To assess the usefulness of Gd-DTPA MRI in the evaluation of the characteristics of intracranial meningiomas and in the correlation with their histopathologic pattern. We retrospectively analyzed the Gd-DTPA MRI findings in 22 cases of histologically-proven intracranial meningiomas. The images were assessed for signal intensity, internal texture, peritumoral edema, and enhancement characteristic. Computed tomograms were obtained in 18 cases and compared with MRI findings. T1-weighted images were not particularly useful for discriminating pathologic subtype, but signal intensity on T2-weighted images were relatively well correlated with histopathologic findings. A heterogeneous texture produced by tumor vascularity, calcification, cystic foci, hemorrhagic necrosis, or psammoma body was relatively well shown on Gd-DTPA T1-weighted image compared with that on T1-or T2-weighted image. Gd-DTPA T1-weighted images revealed a dural tail sign in 19 cases(83%). Angioblastic type was slightly hypointense on T1-weighted image and markedly hyperintense on T2-weighted image. Psammomatous type and fibroblastic type were isotense on both T1-and T2-weighted image. Fibroblastic type was more densely enhanced than the other. The transitional, atypical, and papillary types showed tendency of heterogeneous enhancement. Gd-DTPA MRI was a useful imaging modality in evaluation of the characteristics of meningiomas and correlated well with the pathologic patterns

  6. MRI of double-bundle ACL reconstruction: evaluation of graft findings

    International Nuclear Information System (INIS)

    To demonstrate the magnetic resonance imaging (MRI) findings of double-bundle (DB) anterior cruciate ligament (ACL) reconstruction grafts. Sixty-six patients with DB ACL reconstruction were evaluated with MRI 2 years postoperatively. Graft thickness was measured separately by two musculoskeletal radiologists. The MRI findings of graft disruption, signal intensity (SI) changes, cystic degeneration, arthrofibrosis, and impingement were analyzed. The statistical significance of the association between MRI findings was calculated. The mean anteromedial (AM) graft thickness was reduced 9% and the mean posterolateral (PL) graft thickness was reduced 18% from the original graft thickness. Disruption was seen in 3% of AM grafts and 6% of PL grafts and a partial tear in 8 and 23%, respectively. Both grafts were disrupted in 3% of patients. Increased SI was seen in 14% of intact AM grafts and in 60% of partially torn AM grafts (p = 0.032). In PL grafts the increased SI was seen in 51% of the intact grafts and in 93% of the partially torn grafts (p = 0.005). Cystic degeneration was seen in 8% of AM grafts and in 5% of PL grafts. Diffuse arthrofibrosis was seen in 5% of patients and a localized cyclops lesion in 3% of patients. Impingement of the AM graft was seen in 8% of patients. Both grafts were disrupted in 3% of patients. Also, the frequencies of other complications were low. The use of orthogonal sequences in the evaluation of the PL graft SI seems to cause volume-averaging artefacts. (orig.)

  7. MRI of double-bundle ACL reconstruction: evaluation of graft findings

    Energy Technology Data Exchange (ETDEWEB)

    Kiekara, Tommi; Paakkala, Antti [Tampere University Hospital, Medical Imaging Centre, Tampere (Finland); Jaervelae, Timo [Sports Clinic and Hospital Mehilaeinen, Tampere (Finland); Huhtala, Heini [University of Tampere, School of Health Sciences, Tampere (Finland)

    2012-07-15

    To demonstrate the magnetic resonance imaging (MRI) findings of double-bundle (DB) anterior cruciate ligament (ACL) reconstruction grafts. Sixty-six patients with DB ACL reconstruction were evaluated with MRI 2 years postoperatively. Graft thickness was measured separately by two musculoskeletal radiologists. The MRI findings of graft disruption, signal intensity (SI) changes, cystic degeneration, arthrofibrosis, and impingement were analyzed. The statistical significance of the association between MRI findings was calculated. The mean anteromedial (AM) graft thickness was reduced 9% and the mean posterolateral (PL) graft thickness was reduced 18% from the original graft thickness. Disruption was seen in 3% of AM grafts and 6% of PL grafts and a partial tear in 8 and 23%, respectively. Both grafts were disrupted in 3% of patients. Increased SI was seen in 14% of intact AM grafts and in 60% of partially torn AM grafts (p = 0.032). In PL grafts the increased SI was seen in 51% of the intact grafts and in 93% of the partially torn grafts (p = 0.005). Cystic degeneration was seen in 8% of AM grafts and in 5% of PL grafts. Diffuse arthrofibrosis was seen in 5% of patients and a localized cyclops lesion in 3% of patients. Impingement of the AM graft was seen in 8% of patients. Both grafts were disrupted in 3% of patients. Also, the frequencies of other complications were low. The use of orthogonal sequences in the evaluation of the PL graft SI seems to cause volume-averaging artefacts. (orig.)

  8. The paediatric wrist revisited - findings of bony depressions in healthy children on radiographs compared to MRI

    Energy Technology Data Exchange (ETDEWEB)

    Avenarius, Derk M.F.; Eldevik, Petter [University Hospital North Norway, Department of Radiology, Tromsoe (Norway); Ording Mueller, Lil-Sofie [University Hospital North Norway, Department of Radiology, Tromsoe (Norway); Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); Owens, Catherine M. [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); University College London, Institute of Child Health, London (United Kingdom); Rosendahl, Karen [Haukeland University Hospital, Department of Radiology, Bergen (Norway); University of Bergen, Department of Surgical Sciences, Bergen (Norway); Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom)

    2012-07-15

    The presence of erosions is used for diagnosis and monitoring of disease activity in juvenile idiopathic arthritis (JIA). Assessment of carpal bone erosions in children is challenging due to lack of normal references. To define normal appearances of bony depressions in the wrist on radiographs and MRI. MRI and radiography of the wrist were performed in 88 healthy children, 5-15 years of age. We assessed the number of bony depressions within the carpals/proximal metacarpals on both modalities, separately and combined. A total of 75 carpal depressions were identified on radiography compared to 715 on MRI. The number of bony depressions identified radiographically showed no statistically significant difference across age-groups. Within the metacarpals, there was no significant difference between bony depressions identified by MRI or radiography, except at the bases of the second metacarpal. Bony depressions that resemble erosions are normal findings in the wrist in children. MRI identifies more depressions than radiographs in the carpus. Some bony depressions occur at typical locations and should be accounted for when assessing the wrist in JIA to avoid overstaging. (orig.)

  9. MRI findings in children with neurofibromatosis type 1: a prospective study

    Energy Technology Data Exchange (ETDEWEB)

    Van Es, S. [Dept. of Radiology, Royal Alexandra Hospital for Children, Paramatta (Australia); North, K.N. [Dept. of Neurology, Royal Alexandra Hospital for Children, Paramatta (Australia); McHugh, K. [Dept. of Radiology, Royal Alexandra Hospital for Children, Paramatta (Australia); De Silva, M. [Dept. of Radiology, Royal Alexandra Hospital for Children, Paramatta (Australia)

    1996-07-01

    To determine the frequency and nature of MRI lesions in children with neurofibromatosis type I (NF1), 50 patients aged 8 to 16 years were evaluated prospectively with cranial MRI. Forty-one children were asymptomatic with respect to central nervous system pathology, and 50% were macrocephalic. Sixteen patients (32%) had normal MRI examinations. Thirty-two patients (64%) had high intensity lesions of T2-weighted images and 16 patients (32%) had hyperintense lesions on T1-weighted images. Seven patients (14%) had ventricular dilatation (associated with increased intracranial pressure in 2) and 11 patients (22%) had optic pathway lesions (optic glioma in 7). MRI was superior to CT in differentiating optic sheath thickening and optic nerve tortuosity from optic glioma in four patients. An intracranial tumour (ependymoma) and sphenoid wing dysplasia were evident in individual patients. Findings previously unreported in NF1 included an aqueductal web resulting in hydrocephalus, intracular neurofibroma resulting in retinal detachment, and asymptomatic enlargement of the septum pellucidum. T1 and T2 signal abnormalities in isolation were not associated with neurological deficits or the occurrence of macrocephaly, and all lesions that required intervention were suspected clinically. Macrocephaly in the absence of increased intracranial pressure or accelerated head growth is not an indication for neuroimaging in children with NF1. However, the majority of children (68%) had disease-specific abnormalities and thus MRI may provide a useful adjunct to clinical evaluation in the diagnosis of equivocal cases. (orig.)

  10. The paediatric wrist revisited - findings of bony depressions in healthy children on radiographs compared to MRI

    International Nuclear Information System (INIS)

    The presence of erosions is used for diagnosis and monitoring of disease activity in juvenile idiopathic arthritis (JIA). Assessment of carpal bone erosions in children is challenging due to lack of normal references. To define normal appearances of bony depressions in the wrist on radiographs and MRI. MRI and radiography of the wrist were performed in 88 healthy children, 5-15 years of age. We assessed the number of bony depressions within the carpals/proximal metacarpals on both modalities, separately and combined. A total of 75 carpal depressions were identified on radiography compared to 715 on MRI. The number of bony depressions identified radiographically showed no statistically significant difference across age-groups. Within the metacarpals, there was no significant difference between bony depressions identified by MRI or radiography, except at the bases of the second metacarpal. Bony depressions that resemble erosions are normal findings in the wrist in children. MRI identifies more depressions than radiographs in the carpus. Some bony depressions occur at typical locations and should be accounted for when assessing the wrist in JIA to avoid overstaging. (orig.)

  11. Cine e identidades virtuales

    Directory of Open Access Journals (Sweden)

    Labrador Ben, Julia María

    2006-12-01

    Full Text Available The subject is the ability the cinema has performed - since its very begining - as a creation instrument of national and transnational identities. In the first place, it covers Spanish cinema since 1938 and right after the end of the Spanish Civil War, II World War Italian-German cinema, Eisenstein’s, Leni Riefenstahl’s, Griffth’s and Ford’s cinema, the role American war and science fiction productions played, as well as the comedies dealing with the divided Berlin subject. The role of computers and video-games and the new cinema positionings that forecast the end of what is real, is studied through films such as Tron, The Lawnmower Man, Johnny Mnemonic, Ghost in the shell, Simone o Matrix.Se estudia la capacidad del cine desde sus orígenes como instrumento de generación de identidades nacionales y transnacionales. Se realiza, en primer lugar, un recorrido por el cine español desde 1938 y tras el final de la guerra civil, el cine italo-alemán de la II Guerra Mundial, el cine de Eisenstein, Leni Riefenstahl, Griffth y Ford, y el papel que jugaron las producciones norteamericanas bélicas y de ciencia ficción, así como las comedias sobre el Berlín dividido. El papel de los ordenadores y los videojuegos, y los nuevos planteamientos cinematográficos que pronostican el final de lo real se estudia a través de películas como Tron, El cortador de césped, Johnny Mnemonic, Ghost in the shell, Simone o Matrix.

  12. Do MRI findings identify patients with low back pain or sciatica who respond better to particular interventions? : A systematic review

    DEFF Research Database (Denmark)

    Steffens, Daniel; Hancock, Mark J

    2015-01-01

    PURPOSE: Magnetic resonance imaging (MRI) can reveal a range of degenerative findings and anatomical abnormalities; however, the clinical importance of these remains uncertain and controversial. We aimed to investigate if the presence of MRI findings identifies patients with low back pain (LBP) or sciatica who respond better to particular interventions. METHODS: MEDLINE, EMBASE and CENTRAL databases were searched. We included RCTs investigating MRI findings as treatment effect modifiers for patients with LBP or sciatica. We excluded studies with specific diseases as the cause of LBP. Risk of bias was assessed using the criteria of the Cochrane Back Review Group. Each MRI finding was examined for its individual capacity for effect modification. RESULTS: Eight published trials met the inclusion criteria. The methodological quality of trials was inconsistent. Substantial variability in MRI findings, treatments and outcomes across the eight trials prevented pooling of data. Patients with Modic type 1 when compared with patients with Modic type 2 had greater improvements in function when treated by Diprospan (steroid) injection, compared with saline. Patients with central disc herniation when compared with patients without central disc herniation had greater improvements in pain when treated by surgery, compared with rehabilitation. CONCLUSIONS: Although individual trials suggested that some MRI findings might be effect modifiers for specific interventions, none of these interactions were investigated in more than a single trial. High quality, adequately powered trials investigating MRI findings as effect modifiers are essential to determine the clinical importance of MRI findings in LBP and sciatica (PROSPERO: CRD42013006571).

  13. Cortical restricted diffusion as the predominant MRI finding in sporadic Creutzfeldt-Jakob disease

    Energy Technology Data Exchange (ETDEWEB)

    Talbott, Sabrina D.; Sattenberg, Ronald J.; Heidenreich, Jens O. (Dept. of Radiology, Univ. of Louisville, Louisville (United States)), e-mail: sdtalb02@gwise.louisville.edu; Plato, Brian M (Dept. of Neurology, Univ. of Louisville, Louisville (United States)); Parker, John (Dept. of Pathology and Laboratory Medicine, Univ. of Louisville, Louisville (United States))

    2011-04-15

    Creutzfeldt-Jakob disease is a rare and fatal neurodegenerative disorder with MR findings predominantly limited to the grey matter of the cortex and the basal ganglia. Sporadic Creutzfeldt-Jakob disease can produce a spectrum of MR imaging findings of the brain, most notably on DWI and FLAIR sequences. Involvement of the basal ganglia and neocortex is the most common finding, but isolated involvement of the cortex can also be seen. We describe the clinical history and MRI findings of three patients with sporadic Creutzfeldt-Jakob disease confirmed by brain biopsy or autopsy and review the literature of imaging manifestations of this disease

  14. Macro-regenerative nodules in biliary atresia: CT/MRI findings and their pathological relations

    Directory of Open Access Journals (Sweden)

    Jiun-Lung Liang, Yu-Fan Cheng, Allan M Concejero, Tung-Liang Huang, Tai-Yi Chen, Leo Leung-Chit Tsang, Hsin-You Ou

    2008-07-01

    Full Text Available AIM: To describe the radiological findings of a macro-regenerative nodule (MRN in the liver of pre-transplantation biliary atresia (BA patients and to correlate it with histological findings.METHODS: Between August 1990 and November 2007, 144 BA patients underwent liver transplantation (LT at our institution. The pre-transplantation computer tomography (CT and magnetic resonance imaging (MRI findings were reviewed and correlated with the post-transplantation pathological findings.RESULTS: Nine tumor lesions in 7 patients were diagnosed in explanted livers. The post-transplantation pathological findings showed that all the lesions were MRNs without malignant features. No small nodule was detected by either MRI or CT. Of the 8 detectable lesions, 6 (75% were in the central part of the liver, 5 (63% were larger than 5 cm, 5 (63% had intra-tumor tubular structures, 3 (38% showed enhancing fibrous septa, 3 (38% had arterial enhancement in CT, one (13% showed enhancement in MRI, and one (13% had internal calcifications.CONCLUSION: Although varied in radiological appearance, MRN can be differentiated from hepatocellular carcinoma (HCC in most of BA patients awaiting LT. The presence of an arterial-enhancing nodule does not imply that LT is withheld solely on the basis of presumed malignancy by imaging studies. Liver biopsy may be required in aid of diagnostic imaging to exclude malignancy.

  15. MRI and 1H MRS findings in Smith-Lemli-Opitz syndrome.

    Science.gov (United States)

    Caruso, P A; Poussaint, T Y; Tzika, A A; Zurakowski, D; Astrakas, L G; Elias, E R; Bay, C; Irons, M B

    2004-01-01

    Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive disorder characterized by a defect in cholesterol biosynthesis, associated with mental retardation and multisystem structural abnormalities. This study investigated the prevalence of congenital CNS abnormalities by MRI in a large series of patients with SLOS and the correlation of the clinical and biochemical findings with the results of MRI and 1H MRS. Eighteen patients were studied; all underwent MRI of the brain, and 16 had 1H MRS of the cerebral white matter. The ratios choline:NAA, lipid:NAA, and lipid:choline metabolite were found to be correlated with the clinical degree of disease severity, serum total sterol ratios (cholesterol/cholesterol + 7-dehydrocholesterol + 8-dehydrocholesterol) and in two cases with the effect of cholesterol therapy. Abnormal CNS findings were noted in five patients, including callosal abnormalities (n = 4), Dandy-Walker variant (n = 1), and arachnoid cyst (n = 1). Holoprosencephaly was noted in one patient with a prevalence of 6%. Choline:NAA was elevated in seven patients. There was a statistically significant positive correlation between the lipid:choline ratio and the serum cholesterol precursor, 8-dehydrocholesterol. In two patients 1H MRS demonstrated abnormally elevated lipids prior to cholesterol therapy, which improved on therapy. The use of MRI and 1H MRS is an effective way to demonstrate brain structural abnormalities in patients with SLOS and may prove to be an effective method for the assessment of the effects of cholesterol replacement therapy in the brain. PMID:14605787

  16. MRI and 1H MRS findings in Smith-Lemli-Opitz syndrome

    International Nuclear Information System (INIS)

    Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive disorder characterized by a defect in cholesterol biosynthesis, associated with mental retardation and multisystem structural abnormalities. This study investigated the prevalence of congenital CNS abnormalities by MRI in a large series of patients with SLOS and the correlation of the clinical and biochemical findings with the results of MRI and 1H MRS. Eighteen patients were studied; all underwent MRI of the brain, and 16 had 1H MRS of the cerebral white matter. The ratios choline:NAA, lipid:NAA, and lipid:choline metabolite were found to be correlated with the clinical degree of disease severity, serum total sterol ratios (cholesterol/cholesterol + 7-dehydrocholesterol + 8-dehydrocholesterol) and in two cases with the effect of cholesterol therapy. Abnormal CNS findings were noted in five patients, including callosal abnormalities (n=4), Dandy-Walker variant (n=1), and arachnoid cyst (n=1). Holoprosencephaly was noted in one patient with a prevalence of 6%. Choline:NAA was elevated in seven patients. There was a statistically significant positive correlation between the lipid:choline ratio and the serum cholesterol precursor, 8-dehydrocholesterol. In two patients 1H MRS demonstrated abnormally elevated lipids prior to cholesterol therapy, which improved on therapy. The use of MRI and 1H MRS is an effective way to demonstrate brain structural abnormalities in patients with SLOS and may prove to be an effective method for the assessment of the effects of cholesterol replacement therapy in the brain. (orig.)

  17. A retrospective review of pituitary MRI findings in children on growth hormone therapy

    Energy Technology Data Exchange (ETDEWEB)

    Tsai, Sarah L.; Lawrence, Sarah [University of Ottawa, Division of Endocrinology, Children' s Hospital of Eastern Ontario, Ottawa (Canada); Laffan, Eoghan [Children' s University Hospital, Pediatric Radiology, Dublin 1 (Ireland)

    2012-07-15

    Patients with congenital hypopituitarism might have the classic triad of pituitary stalk interruption syndrome, which consists of: (1) an interrupted or thin pituitary stalk, (2) an absent or ectopic posterior pituitary (EPP), and (3) anterior pituitary hypoplasia or aplasia. To examine the relationship between pituitary anatomy and the degree of hormonal dysfunction. This study involved a retrospective review of MRI findings in all children diagnosed with congenital growth hormone deficiency from 1988 to 2010 at a tertiary-level pediatric hospital. Of the 52 MRIs reviewed in 52 children, 26 children had normal pituitary anatomy and 26 had one or more elements of the classic triad. Fourteen of fifteen children with multiple pituitary hormone deficiencies had structural anomalies on MRI. Twelve of 37 children with isolated growth hormone deficiency had an abnormal MRI. Children with multiple pituitary hormone deficiencies were more likely to have the classic triad than children with isolated growth hormone deficiency. A normal MRI was the most common finding in children with isolated growth hormone deficiency. (orig.)

  18. Isolated lipoma of filum terminale in adults: MRI findings and clinical correlation

    International Nuclear Information System (INIS)

    Fat within the filum terminale is frequently seen on routine magnetic resonance imaging (MRI) of the lumbosacral spine (LSS), with prevalence of 1–5%. The objective of this study was to determine the prevalence and MRI features of isolated lipoma of filum terminale (LFT) in adult population and its correlation with the patient clinical presentations. Prospective analysis of all lumbosacral MRI performed at King Abdullah University Hospital during a 21-month period. A total of 37 patients with LFT were included. Patients were divided into two groups. Group A patients have neurological deficit manifested by either motor, sensory or sphincter abnormality. Group B patients have normal neurological examination. Clinical findings were correlated with: A: thickness of LFT, B: length of LFT, C: distance of LFT from conus medullaris (CM), D: age of the patient. The prevalence of isolated LFT in our study was 3.2%. There was no significant correlation between the thickness or length of LFT and the presence of neurological deficit. The distance of LFT from CM was also not correlated with the patient clinical presentation. No significant difference in the age between the two groups. LFT in adult likely represent an incidental finding on routine lumbosacral MRI. Special attention for LFT in children is mandatory as it may indicate clinical tethering in otherwise normal appearing LSS.

  19. First report of MRI findings in a case of an autoamputated wandering calcified ovary

    Directory of Open Access Journals (Sweden)

    Mahajan PS

    2014-03-01

    Full Text Available Parag Suresh Mahajan, Nazeer Ahamad, Sheik Akbar Hussain Department of Radiology, Al-Khor Hospital, Hamad Medical Corporation, Doha, Qatar Abstract: An autoamputated wandering calcified ovary (AWCO is an extremely rare cause of abdominal calcification in the pediatric population. We present the magnetic resonance imaging (MRI features of AWCO in a child. To our knowledge, the MRI features of AWCO have not been previously described in the published literature. Our case report indicates that the MRI findings are characteristic in the diagnosis of an AWCO and can completely obviate the need for invasive procedures in this mostly benign disease. An AWCO should be considered in all cases of mobile calcific opacities on radiographs in female patients. We advise that MRI be conducted in all suspected cases of AWCO for accurate and noninvasive diagnosis, and regular follow-up should be performed with ultrasound. The findings in our case report have the potential to change the course of investigations and management in suspected cases. Keywords: magnetic resonance imaging, ovary, adnexa, autoamputation, wandering calcification

  20. CT and MRI findings of cerebral ischemic lesions in the cortical and perforating arterial system

    Energy Technology Data Exchange (ETDEWEB)

    Kameyama, Masakuni; Udaka, Fukashi; Nishinaka, Kazuto; Kodama, Mitsuo; Urushidani, Makoto; Kawamura, Kazuyuki; Inoue, Haruhisa; Kageyama, Taku [Sumitomo Hospital, Osaka (Japan)

    1995-07-01

    It is clinically useful to divide the location of infarction into the cortical and perforating arterial system. Computerized tomography (CT) and magnetic resonance imaging (MRI) now make the point of infarction a simple and useful task in daily practice. The diagnostic modality has also demonstrated that risk factors and clinical manifestations are different for infarction in the cortical as opposed to the perforating system. In this paper, we present various aspects of images of cerebral ischemia according to CT and/or MRI findings. With the advance of imaging mechanics, diagnostic capability of CT or/and MRI for cerebral infarction has markedly been improved. We must consider these points on evaluating the previously reported results. In addition, we always consider the pathological background of these image-findings for the precise interpretation of their clinical significance. In some instances, dynamic study such as PET or SPECT is needed for real interpretations of CT and/or MRI images. We paid special reference to lacunar stroke and striatocapsular infarct. In addition, `branch atheromatous disease (Caplan)` was considered, in particular, for their specific clinical significances. Large striatocapsular infarcts frequently show cortical signs and symptoms such as aphasia or agnosia in spite of their subcortical localization. These facts, although have previously been known, should be re-considered for their pathoanatomical mechanism. (author).

  1. Neurolymphomatosis on F 18 FDG PET/CT and MRI Findings: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Chae Moon; Lee, Sang Woo; Lee, Hong Je; Song, Bong Il; Kim, Hae Won; Kang, Sungmin; Jeong, Shin Young; Ahn, Byeong Cheol; Lee, Jaetae; Chae, Yee Soo [Kyungpook National Univ. Hospital, Daegu (Korea, Republic of)

    2011-03-15

    Neurolymphomatosis is a rare manifestation of malignant lymphoma. A 74 year old man, in complete remission from diffuse large B cell lymphoma, presented with a loss of pain and temperature sensation in the left hemiface and left upper extremity, and motor weakness in the left upper and both lower extremities. Cerebrospinal fluid analysis and brain magnetic resonance imaging (MRI) findings were negative. Combined fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) revealed multiple linear hypermetabolic lesions along the mandibular branch of the left trigeminal nerve, left brachial plexus, right adrenal gland, right femoral nerve, and both sciatic nerves, which corresponded to the patient's complex neurologic symptoms. C spine and pelvic MRI revealed diffuse thickening with enhancement in the left sciatic nerve, but negative findings for other sites identified by FDG PET/CT. These findings for other sites identified by FDG PET/CT. These findings suggest that FDG PET/CT can detect peripheral nerve infiltration by malignant lymphoma earlier than MRI. Thus, if a patient with a history of lymphoma presents with neurologic symptoms, FDG PET/CT should be performed to evaluate neurolymphomatosis.

  2. MRI Findings of Cervical Spine Lesions among Symptomatic Patients and Their Risk Factors

    Directory of Open Access Journals (Sweden)

    J. Amir orang

    2003-06-01

    Full Text Available Background: Cervical spine and intervertebral discs are potentially prone to functional disorders. Objectives:This study sought type and distribution of different pathologies in the cervical spine and a possible relationship between the MRI findings and the probable risk factors of the degenerative disorders. Material and methods: This descriptive cross-sectional research was carried out from October 2000 to January 2002 in three referral centers in Tehran. All the patients had referred for cervical MRI for neck pain and/or radicular pain. Results: Totally 342 patients entered the study. Sixty percent of patients were male. The mean age was 55.1 12.1 years. Seventy-nine percent of patients had abnormal MRI findings (238 patients (70% had signs of degenerative processes and 31 patients (9% had the other findings with a total 308 pathologies. The most common findings were disc bulging/ protrusion (%21.1, disc dehydration (%20.1, disc herniation (%18.1, and canal stenosis(%17.5. Older age, male gender and history of neck trauma were associated with increasing probability of degenerative changes (P-Values<0.05. Conclusion: Types of cervical spine pathologies are comparable to other reports. The anatomical distribution of disc bulging and protrusion in our study are similar to other reports. Likewise age, gender and a history of trauma to the neck were closely associated with the degenerative signs on the MR images.

  3. Comparison of MRI findings with clinical symptoms in temporomandibular joint internal derangement

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Ki Jeong [Chonbuk National University College of Medicine, Gwangju (Korea, Republic of)

    2005-06-15

    To determine the clinical correlation of magnetic resonance imaging (MRI) findings of temporomandibular joint internal derangements. The MR images of 150 TMJs in 75 patients were analyzed. The clinical symptoms were pain in the pre auricular area and masticatory muscles and TMJ sounds. There was a statistically significant relationship between the MRI diagnoses of different types of disc displacements and clinical findings of pain, clicking, and crepitus. The risk of TMJ pain was increased when the disc displacement without reduction occurred at the same time in combination with the osteoarthrosis and effusion. Regardless of the results, the data indicate that each of these MR imaging variables may not be regarded as the unique and dominant factor in defining TMJ pain occurrence.

  4. MRI findings of the subacute combined degeneration of the spinal cord : a case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Joo Chang; Cha, Sang Hoon; Lee, Sang Soo; Hun, Bae Il; Han, Gi Seok; Kim, Sung Jin; Park, Kil Sun [College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju (Korea, Republic of)

    2000-05-01

    Subacute combined degeneration (SCD) of the spinal cord is a neurological complication arising from vitamin B{sub 12} deficiency. Typical findings are demyelination and axonal loss of the posterior and lateral columns of the thoracic and cervical spinal cord, leading to sensory ataxia and paresthesia. Clinical and neurological features and MRI findings all contribute to the diagnosis of this entity. In the Korean medical literature, only one case of of SCD involving pre-treatment MRI has been reported. We describe one case of SCD in a post-gastrectomy patient who initially presented with progressive sensory abnormality in both upper and lower extremities and showed T2 hyperintensity in the posterior and lateral columns of the spinal cord; this diminished, with clinical improvement, after vitamin B12 therapy. Our report includes the MR images obtained during follow up. (author)

  5. MRI and US findings of subcutaneous fat necrosis of the newborn

    Energy Technology Data Exchange (ETDEWEB)

    Vasireddy, Syam; Long, Scott D. [Southern Illinois University, Department of Radiology, Springfield, IL (United States); St. John' s Hospital, Department of Radiology, Springfield, IL (United States); Sacheti, Bhavna [Medical College of Wisconsin, Department of Pediatric Critical Care, Milwaukee, WI (United States); Children' s Hospital Wisconsin, Department of Critical Care, Milwaukee, WI (United States); Mayforth, Ruth D. [Southern Illinois University, Department of Surgery, Springfield, IL (United States); St. John' s Hospital, Department of Surgery, Springfield, IL (United States)

    2009-01-15

    Subcutaneous fat necrosis of the newborn (SCFN) is an uncommon, benign disorder found in full-term or post-mature neonates. It usually presents in neonates who have experienced perinatal difficulty such as asphyxia, peripheral hypoxemia, hypothermia, meconium aspiration or trauma. We present a newborn with abnormal findings on MRI and US within the axilla, neck, and abdominal walls that were pathologically proved via biopsy to be subcutaneous fat necrosis. (orig.)

  6. MRI and US findings of subcutaneous fat necrosis of the newborn

    International Nuclear Information System (INIS)

    Subcutaneous fat necrosis of the newborn (SCFN) is an uncommon, benign disorder found in full-term or post-mature neonates. It usually presents in neonates who have experienced perinatal difficulty such as asphyxia, peripheral hypoxemia, hypothermia, meconium aspiration or trauma. We present a newborn with abnormal findings on MRI and US within the axilla, neck, and abdominal walls that were pathologically proved via biopsy to be subcutaneous fat necrosis. (orig.)

  7. Unusual MRI findings of dural arteriovenous fistula: Isolated perfusion lesions mimicking TIA

    OpenAIRE

    Kim Yong-Won; Kang Dong-Hun; Hwang Yang-Ha; Park Sung-Pa

    2012-01-01

    Abstract Background The diagnosis of transient ischemic attack (TIA) based on clinical history and objective findings, even including multiparametric MRI, can be misleading. We report two patients who presented with TIA-like deficits with isolated perfusion lesions in corresponding areas but were finally diagnosed as transient neurological symptoms associated with dural arteriovenous fistula (dAVF). Case presentation Two patients presented with transient focal neurological symptoms lasting le...

  8. CNS changes in Usher's syndrome with mental disorder: CT, MRI and PET findings.

    OpenAIRE

    Koizumi, J; Ofuku, K; Sakuma, K; Shiraishi, H; Iio, M.; Nawano, S

    1988-01-01

    CNS changes in a case of Usher's syndrome associated with schizophrenia-like mental disorder were observed by CT, MRI and PET. The neuro-radiological findings of the case demonstrate the degenerative and metabolic alterations in various regions of cortex, white matter and subcortical areas in the brain. Mental disorder of the case is almost indistinguishable from that of schizophrenia, but the psychotic feature is regarded as an atypical or mixed organic brain syndrome according to the classi...

  9. Identifying biological pathways in the MRI findings of people with low back pain

    DEFF Research Database (Denmark)

    Jensen, Rikke Krüger; Jensen, Tue Secher; Kjær, Per; Kent, Peter

    2012-01-01

    Title Identifying biological pathways in the MRI findings of people with low back pain Authors and affiliations Rikke K Jensen1, Tue Secher Jensen1, Per Kjaer1,2, Peter Kent1 1Research Department, Spine Centre of Southern Denmark, Hospital Lillebaelt, Institute of Regional Health Services Research, University of Southern Denmark, Part of the Clinical Locomotion Network, Middelfart, Denmark. 2Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Part of the Clinic...

  10. Gigantic Intracranial Hydatid Cyst and MRI Findings with a Case Report

    Directory of Open Access Journals (Sweden)

    Mustafa Koç

    2007-12-01

    Full Text Available Hydatid cyst is a parasitic infestation with rare presentation in the cerebrum. Hydatid cyst disease is rare in the cerebrum and lebions are usaally single, accounting for only 1,6-5,2 % of all hydatid cysts. The differential diagnosis of cerebral cystic echinococcosis includes abscess, cystic tumor, arachnoid cyst, and porencephalic cyst. In this report, we aim to present MRI findings of a gigantic intracranial hydatid cyst mass which ihas not been previously described in this size before.

  11. Usual and unusual MRI findings of ovarian fibroma: correlation with pathologic findings.

    Science.gov (United States)

    Kitajima, Kazuhiro; Kaji, Yasushi; Sugimura, Kazuro

    2008-01-01

    Ovarian fibromas typically exhibit low signal intensity on T(2)-weighted images, which reflects their abundant fibrocollagenous stroma. However, the mass of larger tumors often demonstrates high signal intensity on T(2)-weighted images, which reflects varied degenerative changes, such as cystic degeneration, edematous change, hemorrhagic infarction, or necrosis caused by torsion and myxomatous change. We illustrate typical and atypical magnetic resonance (MR) imaging findings of ovarian fibromas and correlate them with histopathologic findings. PMID:18460848

  12. MRI findings of nasopharyngeal carcinoma in patients presenting with ocular sings

    International Nuclear Information System (INIS)

    Objective: To study the MRI features of nasopharyngeal carcinoma (NPC) in patients who presented with ocular abnormalities. Methods: The clinical signs and MRI features of ?, ? and/or ? cranial nerve involvement in 22 cases of histologically proved nasopharyngeal carcinoma were retrospectively analyzed. Results: All 22 cases showed perineural tumor spread along the course of ?, ? and ? cranial nerve, Diplopia was the most common sign, occurred in 14/22 patients. The incidence of incomplete palsy of ?, ? and ? cranial nerve were 16/44, 7/44 and 4/44, respectively. There were four types of abnormal MRI findings: cavernous sinus thickening (10/44) and mass (16/44), superior orbital fissure enlargement (4/44) and abnormal signals (9/44), thickened oculomotor muscles with obscured adjacent fatty space and abnormal enhancement (10/44). The dynamic contrast enhancement patterns of the masses in cavernous sinus and orbital were the same as that of nasopharynx lesions; all appeared as rapid initial enhancement followed by a plateau phase. Conclusion: Oculomotor nerve involvement can be the first clinical signs of NPC, and MRI can show the perineural extension along the ?, ? and ? cranial nerve in NPC. (authors)

  13. MRI findings and spreading patterns of necrotizing external otitis: Is a poor outcome predictable?

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, B.J. [Department of Radiology, Seoul National University College of Medicine, Seoul (Korea, Republic of); Han, M.H. [Department of Radiology, Seoul National University College of Medicine, Seoul (Korea, Republic of) and Clinical Research Institute, Seoul National University Hospital, Seoul (Korea, Republic of) and Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul (Korea, Republic of)]. E-mail: hanmh@radcom.snu.ac.kr; Oh, S.H. [Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Song, J.J. [Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Chang, K.-H. [Department of Radiology, Seoul National University College of Medicine, Seoul (Korea, Republic of); Clinical Research Institute, Seoul National University Hospital, Seoul (Korea, Republic of); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul (Korea, Republic of)

    2006-06-15

    AIM: To evaluate spreading patterns of necrotizing external otitis (NEO) by magnetic resonance imaging (MRI) and to identify spreading patterns related to a poor outcome. MATERIALS AND METHODS: Fourteen patients with NEO were divided into good and poor outcome groups according to their final clinical outcomes. Initial MRI images were retrospectively reviewed for regional abnormalities, and follow-up MRI images were reviewed for ICA flow void abnormality and for the following five spreading patterns: medial, crossed, anterior, intracranial, and combined. The frequencies of the abnormal flow void or spreading patterns were compared between the good and poor response groups. RESULTS: Seven (50%) and seven (50%) patients were respectively allocated to the good and poor outcome groups. Retrocondylar fat infiltration was the most commonest finding on initial MRI images (93%). The frequencies of the abnormal flow void and spreading patterns in the good and poor groups, respectively, were: abnormal flow void, 0 and four (57%); anterior, two (29%) and three (43%); medial, six (86%) and seven (100%); crossed, six (86%) and seven (100%); intracranial middle cranial fossa, one (14%) and four (57%); intracranial posterior cranial fossa, four (57%) and six (86%); intracranial foramen magnum, one (14%) and six (86%). CONCLUSIONS: NEO almost always involves the retrocondylar fat and spreads via various pathways to extracranial or intracranial spaces. The presence of an abnormal flow void and intracranial dural enhancement, particularly in the middle cranial fossa and foramen magnum, may indicate a poor prognosis.

  14. Review of MRI Technique and imaging findings in athletic pubalgia and the “sports hernia”

    International Nuclear Information System (INIS)

    The clinical syndrome of athletic pubalgia has prematurely ended many promising athletic careers, has made many active, fitness conscious adults more sedentary, and has served as a diagnostic and therapeutic conundrum for innumerable trainers and physicians worldwide for decades. This diagnosis actually arises from one or more lesions within a spectrum of musculoskeletal and visceral injuries. In recent years, MRI has helped define many of these syndromes, and has proven to be both sensitive and specific for numerous potential causes of athletic pubalgia. This text will provide a comprehensive, up to date review of expected and sometimes unexpected MRI findings in the setting of athletic pubalgia, and will delineate an imaging algorithm and MRI protocol to help guide radiologists and other clinicians dealing with refractory, activity related groin pain in an otherwise young, healthy patient. There is still more to be learned about prevention and treatment plans for athletic pubalgia lesions, but accurate diagnosis should be much less nebulous and difficult with the use of MRI as a primary imaging modality.

  15. Review of MRI Technique and imaging findings in athletic pubalgia and the “sports hernia”

    Energy Technology Data Exchange (ETDEWEB)

    Mullens, Frank E. [Department of Radiology, Thomas Jefferson University, Philadelphia, PA (United States); Zoga, Adam C., E-mail: Adam.zoga@jefferson.edu [Department of Radiology, Thomas Jefferson University, Philadelphia, PA (United States); Morrison, William B. [Department of Radiology, Thomas Jefferson University, Philadelphia, PA (United States); Meyers, William C. [Chairman of Surgery, Drexel University College of Medicine, Philadelphia, PA (United States)

    2012-12-15

    The clinical syndrome of athletic pubalgia has prematurely ended many promising athletic careers, has made many active, fitness conscious adults more sedentary, and has served as a diagnostic and therapeutic conundrum for innumerable trainers and physicians worldwide for decades. This diagnosis actually arises from one or more lesions within a spectrum of musculoskeletal and visceral injuries. In recent years, MRI has helped define many of these syndromes, and has proven to be both sensitive and specific for numerous potential causes of athletic pubalgia. This text will provide a comprehensive, up to date review of expected and sometimes unexpected MRI findings in the setting of athletic pubalgia, and will delineate an imaging algorithm and MRI protocol to help guide radiologists and other clinicians dealing with refractory, activity related groin pain in an otherwise young, healthy patient. There is still more to be learned about prevention and treatment plans for athletic pubalgia lesions, but accurate diagnosis should be much less nebulous and difficult with the use of MRI as a primary imaging modality.

  16. Modified Classification of MRI Findings to Predict Histologic Grading of Liposarcomas

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Tae Yong; Lee, In Sook; Hwang, In Kyung; Choi, Yoon Young [Pusan National University Yangsan Hospital, Yangsan (Korea, Republic of); Yang, Ik [Hallym University Medical Center, Seoul (Korea, Republic of); Lee, Sun Joo [Inje University Paik Hospital, Busan (Korea, Republic of)

    2010-04-15

    To predict the histopathologic grading of liposarcomas with the modified classification of MRI findings. The 47 MRI studies of pathologically confirmed liposarcomas were retrospectively analyzed, and found to have well-differentiated (n=17) and myxoid (n=16) types, representing the 'low grade' sarcomas, as well as the round cell (n=9) and pleomorphic (n=5) types, which represent the 'high grade' sarcomas. The MRI findings of liposarcomas were classified into four groups as the one with fat signal above 80%, 20-80%, below 20%, and no fat signal on T1-weighted images (WIs), into three groups as the one with high signals with reticular or irregular lines, homogeneous above 50% of the area, and heterogeneous above 50% on the T2WIs, and into three groups as the one enhanced with reticular or irregular lines and enhancement areas above 50% and below 50% on the Gd-DTPA T1WIs. The sarcomas with a lower amount of fat signals on T1WIs had a significantly higher histologic grade (p = 0.026) and also showed heterogeneous high signals above 50% on the T2WIs was statistically significant difference (p =0.010) but not on the contrast enhanced T1WIs (p = 0.070). The modified classification of the MR findings could help predict the histologic grading of liposarcomas

  17. Modified Classification of MRI Findings to Predict Histologic Grading of Liposarcomas

    International Nuclear Information System (INIS)

    To predict the histopathologic grading of liposarcomas with the modified classification of MRI findings. The 47 MRI studies of pathologically confirmed liposarcomas were retrospectively analyzed, and found to have well-differentiated (n=17) and myxoid (n=16) types, representing the 'low grade' sarcomas, as well as the round cell (n=9) and pleomorphic (n=5) types, which represent the 'high grade' sarcomas. The MRI findings of liposarcomas were classified into four groups as the one with fat signal above 80%, 20-80%, below 20%, and no fat signal on T1-weighted images (WIs), into three groups as the one with high signals with reticular or irregular lines, homogeneous above 50% of the area, and heterogeneous above 50% on the T2WIs, and into three groups as the one enhanced with reticular or irregular lines and enhancement areas above 50% and below 50% on the Gd-DTPA T1WIs. The sarcomas with a lower amount of fat signals on T1WIs had a significantly higher histologic grade (p = 0.026) and also showed heterogeneous high signals above 50% on the T2WIs was statistically significant difference (p =0.010) but not on the contrast enhanced T1WIs (p = 0.070). The modified classification of the MR findings could help predict the histologic grading of liposarcomas

  18. CineGlob

    CERN Multimedia

    CineGlob

    2014-01-01

    CERN will be hosting the next CineGlobe International Film Festival from March 18 to 23 at the Globe of Science and Innovation with the theme “Beyond the Frontier”, This 4th edition will see 66 short films “inspired by science” in competition, including fiction films as well as documentaries. From Tuesday the 18th to Friday the 21st, special lunch sessions are organized from 12:30 to 13:30. Food will be available for purchase at the tent “Café Cinéma” next to the Globe. Special evenings While the short film screenings are the heart of the festival, every year CineGlobe also organizes compelling special events every night, from feature films to special musical performances: Tuesday 18th: The Swiss premiere of the acclaimed documentary film Particle Fever. Presented by BBC Storyville with Fabiola Gianotti and director Mark Levinson in attendance; Wednesday 19th: The result of the “Story Matter” Hacka...

  19. Dynamic enhanced MRI of the subacromial bursa: correlation with arthroscopic and histological findings

    International Nuclear Information System (INIS)

    Objective: To assess dynamic MRI with Gd-DTPA enhancement for evaluating inflammatory changes in the subacromial bursa. Design and patients: We detected the signal intensity changes in dynamic MRI of the subacromial bursa, and confirmed these macroscopically by arthroscopy and histologically. The signal intensity was measured using built-in software, and the enhancement ratio (E ratio) was calculated from dynamic MR images. In addition, as a parameter of the rate of the increase in the signal intensity from 0 to 80 s, the mean increase per second in the E ratio was obtained as the coefficient of enhancement (CE). The correlation was studied of the E ratio and CE with the arthroscopic findings (redness, villous formation, thickening and adhesion), and of the E ratio and CE with the histological findings (capillary proliferation, papillary hyperplasia, fibrosis and inflammatory cell infiltration) of the subacromial bursa. Of patients with shoulder pain, this study included those with rotator cuff injury; patients with rheumatoid arthritis or pitching shoulder disorders were excluded. There were 27 patients (15 men, 12 women) ranging in age from 25 to 73 years (mean 49.1 years). Dynamic MRI of the shoulder was also performed on the healthy side of 10 patients and in five normal young volunteers. Results and conclusions: Changes in signal intensity on dynamic MRI were measured in the subacromial bursa. The E ratio (80 s) and CE (0-80 s) were significantly correlated with redness and villous formation as arthroscopic findings, positively correlated with capillary proliferation and papillary hyperplasia as histological findings (p < 0.05), and negatively correlated with fibrosis as a histological finding (p < 0.05) in the subacromial bursa. The patterns of dynamic curves were well correlated with the bursoscopic and histological findings of the synovium of the subacromial bursa. Dynamic MRI appears to correlate with inflammatory activity of synovium of the subacromial bursa. Clarifying the state of the synovium of the subacromial bursa may be useful in determining therapeutic strategies (e.g., indicating topical infusion of hyaluronic acid or steroids for preservative treatment and selecting the site). Furthermore, the evaluation may be useful for indicating surgery, selecting the technique, and evaluating preoperative and postoperative inflammatory changes. (orig.)

  20. Dynamic enhanced MRI of the subacromial bursa: correlation with arthroscopic and histological findings

    Energy Technology Data Exchange (ETDEWEB)

    Matsuzaki, S. [Dept. of Radiology, Osaka Kosei-nenkin Hospital (Japan); Yoneda, M. [Shoulder and Sports Medicine Service, Osaka Kosei-nenkin Hospital, Osaka City, Osaka (Japan); Kobayashi, Y. [Dept. of Pathology, Osaka Kosei-nenkin Hospital (Japan); Fukushima, S. [Dept. of Orthopaedic Surgery, Sapporo Tokeidai Hospital, Osaka (Japan); Wakitani, S. [Dept. of Orthopaedic Surgery, Shinsyu Univ., Matsumato (Japan)

    2003-09-01

    Objective: To assess dynamic MRI with Gd-DTPA enhancement for evaluating inflammatory changes in the subacromial bursa. Design and patients: We detected the signal intensity changes in dynamic MRI of the subacromial bursa, and confirmed these macroscopically by arthroscopy and histologically. The signal intensity was measured using built-in software, and the enhancement ratio (E ratio) was calculated from dynamic MR images. In addition, as a parameter of the rate of the increase in the signal intensity from 0 to 80 s, the mean increase per second in the E ratio was obtained as the coefficient of enhancement (CE). The correlation was studied of the E ratio and CE with the arthroscopic findings (redness, villous formation, thickening and adhesion), and of the E ratio and CE with the histological findings (capillary proliferation, papillary hyperplasia, fibrosis and inflammatory cell infiltration) of the subacromial bursa. Of patients with shoulder pain, this study included those with rotator cuff injury; patients with rheumatoid arthritis or pitching shoulder disorders were excluded. There were 27 patients (15 men, 12 women) ranging in age from 25 to 73 years (mean 49.1 years). Dynamic MRI of the shoulder was also performed on the healthy side of 10 patients and in five normal young volunteers. Results and conclusions: Changes in signal intensity on dynamic MRI were measured in the subacromial bursa. The E ratio (80 s) and CE (0-80 s) were significantly correlated with redness and villous formation as arthroscopic findings, positively correlated with capillary proliferation and papillary hyperplasia as histological findings (p < 0.05), and negatively correlated with fibrosis as a histological finding (p < 0.05) in the subacromial bursa. The patterns of dynamic curves were well correlated with the bursoscopic and histological findings of the synovium of the subacromial bursa. Dynamic MRI appears to correlate with inflammatory activity of synovium of the subacromial bursa. Clarifying the state of the synovium of the subacromial bursa may be useful in determining therapeutic strategies (e.g., indicating topical infusion of hyaluronic acid or steroids for preservative treatment and selecting the site). Furthermore, the evaluation may be useful for indicating surgery, selecting the technique, and evaluating preoperative and postoperative inflammatory changes. (orig.)

  1. MRI-findings of nodular lesions in an enlarged spleen, associated with visceral Leishmaniasis

    Energy Technology Data Exchange (ETDEWEB)

    Raeymaeckers, Steven, E-mail: Steven.Raeymaeckers@vub.ac.be [ZNA Middelheim, Lindendreef 1, 2020 Antwerpen (Belgium); Docx, Martine; Demeyere, Nathan [ZNA Middelheim, Lindendreef 1, 2020 Antwerpen (Belgium)

    2012-10-15

    Highlights: ? We confirm a previous report that infection with Leishmania can manifest multiple nodular lesions of the spleen. ? We confirm these lesions to be readily detectable with present imaging modalities. ? We affirm the fact that these lesions are hypoechoic on ultrasound, though in our case no hypoechoic halo was observed. ? We found these lesions to be hypodense on CT in the delayed phase after intravenous contrast administration. ? In addition to these previous findings we found that the spleen showed an inhomogeneous intensity on MRI; upon closer examination whilst scrolling through the T2-weighted sequences we can note multiple ill-defined and heterogeneous hypointense nodules. -- Abstract: We present a case of a 15-month-old Moroccan girl with fever of unknown origin, hepatosplenomegaly and multiple hypoechoic nodular splenic lesions that appear hypodense on CT. T2-weighted MRI sequences show a markedly inhomogeneous intensity of the parenchyma, seemingly caused by multiple ill-defined and heterogeneous hypointense nodules. Laboratory tests confirmed a recent infection with Leishmania, a parasite endemic to (sub)tropic regions. During and after therapy these lesions gradually resolved. To our knowledge this is the second published case in which different imaging modalities were able to demonstrate organ lesions associated with Leishmania. It is also the first report of MRI-findings associated with these lesions.

  2. MRI-findings of nodular lesions in an enlarged spleen, associated with visceral Leishmaniasis

    International Nuclear Information System (INIS)

    Highlights: ? We confirm a previous report that infection with Leishmania can manifest multiple nodular lesions of the spleen. ? We confirm these lesions to be readily detectable with present imaging modalities. ? We affirm the fact that these lesions are hypoechoic on ultrasound, though in our case no hypoechoic halo was observed. ? We found these lesions to be hypodense on CT in the delayed phase after intravenous contrast administration. ? In addition to these previous findings we found that the spleen showed an inhomogeneous intensity on MRI; upon closer examination whilst scrolling through the T2-weighted sequences we can note multiple ill-defined and heterogeneous hypointense nodules. -- Abstract: We present a case of a 15-month-old Moroccan girl with fever of unknown origin, hepatosplenomegaly and multiple hypoechoic nodular splenic lesions that appear hypodense on CT. T2-weighted MRI sequences show a markedly inhomogeneous intensity of the parenchyma, seemingly caused by multiple ill-defined and heterogeneous hypointense nodules. Laboratory tests confirmed a recent infection with Leishmania, a parasite endemic to (sub)tropic regions. During and after therapy these lesions gradually resolved. To our knowledge this is the second published case in which different imaging modalities were able to demonstrate organ lesions associated with Leishmania. It is also the first report of MRI-findings associated with these lesions

  3. Congenital muscular dystrophy with merosin deficiency: MRI findings in five patients

    International Nuclear Information System (INIS)

    We present the MRI findings in five patients with congenital muscular dystrophy (CMD) and merosin (laminin ? 2) deficiency, which was total in one and partial in four. In one patient with partial merosin deficiency, MRI was normal. The other four patients had supratentorial white matter abnormalities. In three, T2-weighted images revealed subcortical, deep lobar and periventricular high signal in white matter, while in the other there were only small peritrigonal areas of increased signal. On T1-weighted images, there was slightly low signal. Cortical abnormalities were absent. None of these changes were accompanied by symptoms or signs of central nervous system involvement. White matter abnormalities in a patient with CMD should prompt investigation of merosin. (orig.)

  4. CT and MRI findings in patients with hyperglycemic encephalopathy : three cases report

    International Nuclear Information System (INIS)

    We describe the distinctive brain CT and MRI findings seen in the putamen of three patients with hyperglycemia. The chief complaint of these patients was either chorea (n=3D1) or mental change (n=3D2). They showed hyperglycemia, but physical examination and laboratory data revealed no other abnormalities. In all patients, non-enhanced CT scanning revealed high-attenuated lesions in the unilateral putamen. In two of the three patients, brain MRI performed two days after the onset of symptoms showed an abnormally high signal on T1-weighted images and a low signal on T2-weighted images. One patient had a history of diabetes mellitus, and another had acute myocardiac infarction. The third had no specific history. After the correction of hyperglycemia, the patient's symptoms subsided and diabetes mellitus was diagnosed. (author)

  5. Epstein-Barr virus encephalitis: findings of MRI, MRS, diffusion and perfusion.

    Science.gov (United States)

    Ozbek, Orhan; Koç, Osman; Paksoy, Yahya; Aydin, Kür?ad; Nayman, Alaaddin

    2011-01-01

    Epstein-Barr virus is an infection that is known as infectious mononucleosis. Even though the central nervous system is not a primary region of involvement of this disease, neurological complications are reported rarely. In this case report, we evaluated a 15-month-old male who presented to the pediatric neurology clinic due to high fever and a neurologic attack. His serological tests and radiological examinations (magnetic resonance imaging (MRI), MR spectroscopy (MRS), diffusion-weighted imaging (DWI) and MR perfusion) were consistent with Epstein-Barr virus encephalitis, which is a very rare complication of infectious mononucleosis. Additionally, we discuss the MRI, MRS, DWI and MR perfusion findings of our case, which were different from other cases reported in the literature. PMID:22389991

  6. MRI Findings of Juvenile Xanthogranuloma of the Spinal Cord: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Se Young; Park, Hee Jin; Lee, So Yeon; Chung, Eun Chul; Park, Hae Won; Kook, Shin Ho; Rho, Myung Ho; Goo, Ji Hye [Dept. of Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2013-03-15

    Juvenile xanthogranuloma (JXG) is a proliferative histiocytic disorder experienced during childhood and adolescents. JXG commonly presents as a solitary cutaneous lesion. Despite the term 'juvenile', development of the disease during adulthood is possible, although spinal JXG is extremely rare in adults. We describe a 67-year-old female patient who presented with an intradural-extramedullary (IDEM) tumor of the spinal cord. Magnetic resonance imaging (MRI) findings indicative of JXG of the spinal cord were seen, which was then confirmed pathologically. A lumbar spinal MRI with contrast enhancement showed an oval-shaped, well-defined IDEM tumor at the L1 level. This tumor had mixed signal intensity on the T1-weighted image and high signal intensity on the T2-weighted image. Central homogenous enhancement was observed after contrast administration.

  7. MRI and {sup 1}H MRS findings in Smith-Lemli-Opitz syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Caruso, P.A. [Department of Radiology, Massachusetts Eye and Ear Infirmary, Boston, MA (United States); Harvard Medical School, Boston, MA (United States); Poussaint, T.Y. [Department of Radiology, Children' s Hospital, 300 Longwood Avenue, MA 02115, Boston (United States); Tzika, A.A.; Astrakas, L.G. [Department of Surgery, Massachusetts General Hospital, Boston, MA (United States); Zurakowski, D. [Department of Biostatistics, Children' s Hospital Boston, Boston, MA (United States); Elias, E.R. [Department of Pediatrics and Genetics, Children' s Hospital, Denver, CO (United States); School of Medicine, University of Colorado, Denver, CO (United States); Bay, C. [Department of Medical Genetics, Children' s Hospital of Pittsburgh, Pittsburgh, PA (United States); Irons, M.B. [Division of Clinical Genetics and Metabolism, Children' s Hospital Boston, Boston, MA (United States)

    2004-01-01

    Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive disorder characterized by a defect in cholesterol biosynthesis, associated with mental retardation and multisystem structural abnormalities. This study investigated the prevalence of congenital CNS abnormalities by MRI in a large series of patients with SLOS and the correlation of the clinical and biochemical findings with the results of MRI and {sup 1}H MRS. Eighteen patients were studied; all underwent MRI of the brain, and 16 had {sup 1}H MRS of the cerebral white matter. The ratios choline:NAA, lipid:NAA, and lipid:choline metabolite were found to be correlated with the clinical degree of disease severity, serum total sterol ratios (cholesterol/cholesterol + 7-dehydrocholesterol + 8-dehydrocholesterol) and in two cases with the effect of cholesterol therapy. Abnormal CNS findings were noted in five patients, including callosal abnormalities (n=4), Dandy-Walker variant (n=1), and arachnoid cyst (n=1). Holoprosencephaly was noted in one patient with a prevalence of 6%. Choline:NAA was elevated in seven patients. There was a statistically significant positive correlation between the lipid:choline ratio and the serum cholesterol precursor, 8-dehydrocholesterol. In two patients {sup 1}H MRS demonstrated abnormally elevated lipids prior to cholesterol therapy, which improved on therapy. The use of MRI and {sup 1}H MRS is an effective way to demonstrate brain structural abnormalities in patients with SLOS and may prove to be an effective method for the assessment of the effects of cholesterol replacement therapy in the brain. (orig.)

  8. Acetabular stress fractures in military endurance athletes and recruits: incidence and MRI and scintigraphic findings

    International Nuclear Information System (INIS)

    Objective: To evaluate the incidence and the MRI and scintigraphic appearance of acetabular stress (fatigue) fractures in military endurance athletes and recruits. Design and patients: One hundred and seventy-eight active duty military endurance trainees with a history of activity-related hip pain were evaluated by both MRI and bone scan over a 2-year period. Patients in the study ranged in age from 17 to 45 years. They had hip pain related to activity and had plain radiographs of the hip and pelvis that were interpreted as normal or equivocal. The study was originally designed to evaluate the MRI and scintigraphic appearance of femoral neck stress fractures. Patients had scintigraphy and a limited MRI examination (coronal imaging only) within 48 h of the bone scan. Twelve patients demonstrated imaging findings compatible with acetabular stress fractures. Results: Stress fractures are common in endurance athletes and in military populations; however, stress fracture of the acetabulum is uncommon. Twelve of 178 patients (6.7%) in our study had imaging findings consistent with acetabular stress fractures. Two patterns were identified. Seven of the 12 (58%) patients had acetabular roof stress fractures. In this group, two cases of bilateral acetabular roof stress fractures were identified, one with a synchronous tensile sided femoral neck stress fracture. The remaining five of 12 (42%) patients had anterior column stress fractures, rarely occurring in isolation, and almost always occurring with inferior pubic ramus stress fracture (4 of 5, or 80%). One case of bilateral anterior column stress fractures was identified without additional sites of injury. Conclusions: Stress fractures are commonplace in military populations, especially endurance trainees. Acetabular stress fractures are rare and therefore unrecognized, but do occur and may be a cause for activity-related hip pain in a small percentage of military endurance athletes and recruits. (orig.)

  9. MRI findings in soccer players with long-standing adductor-related groin pain and asymptomatic controls

    DEFF Research Database (Denmark)

    Branci, Sonia; Thorborg, Kristian

    2015-01-01

    BACKGROUND: Soccer players are commonly affected by long-standing adductor-related groin pain (ARGP), but the clinical significance of MRI findings in these athletes is largely unknown. Our aims were (1) to evaluate whether MRI findings are associated with long-standing ARGP in soccer players, (2) to assess MRI findings in asymptomatic soccer players and non-soccer playing controls. METHODS: This cross-sectional study included 28 male soccer players with long-standing ARGP, 17 male asymptomatic soccer players and 20 male asymptomatic non-soccer playing athletes of matching age and athletic exposure. Participants underwent identical standardised and reliable clinical examination, and MRI scans (3?T) of the pelvis performed by a blinded observer. Images were consensus rated by three blinded radiologists according to a standardised MRI evaluation protocol. The associations between clinical adductor-related findings and pathological MRI findings were investigated with ?(2) statistics and OR. RESULTS: Central disc protrusion (p=0.027) and higher grades of pubic bone marrow oedema (BMO; p=0.027) were significantly more present in symptomatic players than asymptomatic players. However, up to 71% of asymptomatic soccer players displayed different positive MRI findings, and asymptomatic soccer players had significantly higher odds (OR ranging from 6.3 to 13.3) for BMO, adductor tendinopathy and degenerative changes than non-soccer players. CONCLUSIONS: ARGP in soccer players was associated with central disc protrusion and higher grades of pubic BMO. Moreover, positive MRI findings were significantly more frequent in soccer players compared with non-soccer players irrespective of symptoms, suggesting that these MRI changes may be associated with soccer play itself rather than clinical symptoms.

  10. Extraspinal incidental findings on routine MRI of lumbar spine: Prevalence and reporting Rates in 1278 patients

    Energy Technology Data Exchange (ETDEWEB)

    Tuncel, Sedat Alpaslan; Cagli, Bekir; Tekatas, Aslan; Kirici, Yadigar Mehmet; Unlu, Ercument; Genchellac, Haken [Trakya University Faculty of Medicine, Balkan Campus, Edirne (Turkmenistan)

    2015-08-15

    The aim of the present study was to determine the prevalence and reporting rate of incidental findings (IF) in adult outpatients undergoing lumbar magnetic resonance imaging (MRI). Re-evaluation of a total of 1278 lumbar MRI images (collected from patients with a mean age of 50.5 years, range 16-91 years) captured between August 2010-August 2011 was done by a neuroradiologist and a musculoskeletal radiologist. IFs were classified according to organ or system (liver, gallbladder, kidney, bladder, uterus, ovary, lymph node, intestine and aorta). The rate of reporting of a range of IF was examined. The outcome of each patient's treatment was evaluated based on review of hospital records and by telephone interviews. A total of 253 IFs were found in 241 patients (18.8% of 1278). Among these, clinically significant IFs (n = 34) included: 2 renal masses (0.15%), 2 aortic aneurysms (0.15%), 2 cases of hydronephrosis (0.15%), 11 adrenal masses (0.86%), 7 lymphadenopathies (0.55%), 6 cases of endometrial or cervical thickening (0.47%), 1 liver hemangioma (0.08%), 1 pelvic fluid (0.08%) and 2 ovarian dermoid cysts (0.15%). Overall, 28% (71/253) of IFs were included in the clinical reports, while clinically significant findings were reported in 41% (14/34) of cases. Extraspinal IFs are commonly detected during a routine lumbar MRI, and many of these findings are not clinically significant. However, IFs including clinically important findings are occasionally omitted from formal radiological reports.

  11. Serial MRI and MRS studies with unusual findings in Rasmussen's encephalitis

    International Nuclear Information System (INIS)

    Rasmussen's syndrome is characterized by intractable seizures and progressive neuropsychiatric deterioration secondary to unilateral cortical inflammation and tissue destruction. Diagnosis of Rasmussen's syndrome in the early phase depends mainly on the clinical features. Neuroimaging and histopathologic examinations may not be specific during this period. We report a case of Rasmussen's syndrome followed by serial MRI and magnetic resonance spectroscopy (MRS) studies over a 3- to 16-month period. A healthy 6-year-old boy presented with focal motor seizures. An MRI study demonstrated prominent enlargement and T2 hyperintensity of the left mesial temporal lobe and perisylvian region. This early finding evolved to volume loss and later progressive atrophy of the ipsilateral hemisphere when epilepsia partialis continua occurred. Being aware of those early MRI features in a patient with increasing frequency of focal motor seizures should suggest Rasmussen's syndrome. In addition, we found prominently increased myoinositol concentration in atrophic cortex which might reflect increased gliosis in the late period of the disease. (orig.)

  12. Extra-mammary incidental findings on 3.0 Tesla dynamic breast MRI: a pictorial essay

    International Nuclear Information System (INIS)

    Full text: Introduction: Dynamic magnetic resonance imaging (MRI) has an ever increasing role in diagnosis of the breast diseases. Although this imaging modality is specific to the pathologies of the breast paranchima, it also provides a large view for evaluating extramammary fields like thorax, a portion of upper abdomen, osseous, vascular and neuronal structures. Objectives and tasks: To discuss 3.0 Tesla dynamic MRI features of some extra-mammary lesions which were incidentally detected at our department in the light of their other imaging modality findings. Materials and methods: The breast MRI examinations which were performed for any reason in our department, were reviewed retrospectively. Incidentally detected extra-mammarian pathologies were defined. If they exist, computed tomography (CT) images of these pathologies were added. Results: MR and CT images of the cases who have liver, kidney, bone, lung, vascular and neuronal pathologies which were incidentally detected, were shared and these images have been worked up into a pictorial essay. Conclusion: The pathologies which were detected at extra-mammarian sites may be clinically relevant, and they can be cause big changes in treatment and follow-up of the patients with or without breast cancer. Because of that, these pathologies must certainly be mentioned in the reports

  13. Armor-piercing bullet: 3-T MRI findings and identification by a ferromagnetic detection system.

    Science.gov (United States)

    Karacozoff, Alexandra M; Pekmezci, Murat; Shellock, Frank G

    2013-03-01

    The objective of this project was to evaluate magnetic resonance imaging (MRI) issues at 3 T for an armor-piercing bullet and to determine if this item could be identified using a ferromagnetic detection system. An armor-piercing bullet (.30 caliber, 7.62 × 39, copper-jacketed round, steel core; Norinco) underwent evaluation for magnetic field interactions, heating, and artifacts using standardized techniques. Heating was assessed with the bullet in a gelled-saline-filled phantom with MRI performed using a transmit/receive radio frequency body coil at a whole-body-averaged specific absorption rate of 2.9 W/kg for 15 minutes. Artifacts were characterized using T1-weighted spin echo and gradient echo pulse sequences. In addition, a special ferromagnetic detection system (Ferroguard Screener; Metrasens, Lisle, Illinois) was used in an attempt to identify this armor-piercing bullet. The findings indicated that the armor-piercing bullet showed substantial magnetic field interactions. Heating was not excessive. Artifacts were large and may create diagnostic problems if the area of interest is close to this bullet. The ferromagnetic detection system yielded a positive result. We concluded that this armor-piercing bullet is MR unsafe. Importantly, this ballistic item was identified using the particular ferromagnetic detection system utilized in this investigation, which has important implications for MRI screening and patient safety. PMID:23707130

  14. Little Leaguer's shoulder (proximal humeral epiphysiolysis): MRI findings in four boys

    International Nuclear Information System (INIS)

    Shoulder pain is a common problem among adolescent athletes. A possible cause of such pain that can be diagnosed on MRI is a stress injury to the proximal humerus known as Little Leaguer's shoulder (proximal humeral epiphysiolysis). Our objective was to describe the MRI appearance of Little Leaguer's shoulder. Four patients (all boys; age range 11-15 years; median 13 years) with clinical, plain radiographic, and MR imaging findings of Little Leaguer's shoulder were studied retrospectively. MRI demonstrated focal physeal widening in all four boys with extension of physeal signal intensity into the metaphysis on T1-weighted and gradient echo coronal and sagittal sequences. T2-weighted sequences were of limited use in demonstrating the physeal widening, which is critical to the diagnosis. Abnormal high T2-signal intensity was seen in the metaphysis adjacent to the focal physeal widening in all the boys. Focal extension of normal physeal T1-weighted and gradient echo signal intensity into the adjacent metaphysis is a sign of stress injury in the proximal humeral physis (Little Leaguer's shoulder). Children should suspend the offending sport to allow healing. (orig.)

  15. A controlled study of reliability and validity of MRI findings in neuro-Behcet's disease

    International Nuclear Information System (INIS)

    Our aim was to test the reliability of interpreting MRI studies in neuro-Behcet's disease (NBD) and to determine the sensitivity and specificity of different MRI findings. We prospectively studied 50 patients: 24 had chronic NBD, 12 multiple sclerosis, 5 vasculitis other than Behcet's disease (BD) and 9 patients had BD without neurological involvement. MRI studies were performed according to a standard protocol with a 0.2 T imager. Two neuroradiologists, blinded to the diagnosis, age and sex of the subjects, reviewed the films independently, twice. Separate assessments were made for a set of items: dural sinus pathology, widening of ventricles and sulci, brain stem atrophy, lesions of the cerebral cortex, discrete lesions of deep white matter, basal ganglia, brain stem and cerebellum and the presence of smooth periventricular high-signal foci. Intraobserver agreement was substantial or better, and interobserver agreement moderate to substantial for most items. In these patients with chronic NBD we found low sensitivity on all assessed items. Dural sinus pathology or brain stem atrophy were highly specific, but parenchymal lesions in different sites had uniformly low specificity. (orig.). With 3 tabs

  16. Acute patellofemoral pain: aggravating activities, clinical examination, MRI and ultrasound findings

    DEFF Research Database (Denmark)

    Brushoj, C.; Holmich, P.

    2008-01-01

    Objective: To investigate acute anterior knee pain caused by overuse in terms of pain location, aggravating activities, findings on clinical examination and ultrasound/MRI examination. To determine if acute anterior knee pain caused by overuse should be classified as a subgroup of patellofemoral pain syndrome (PFPS). Methods: In a observational study design 30 army recruits with anterior knee pain (mean duration of pain 4 weeks) were examined using the PFPS pain severity scale (PSS), knee pain diagrams, standardised clinical examination, ultrasound and MRI examinations. Results: On PSS typical knee loading activities were the most painful, while sitting with knee bend for prolonged time caused surprisingly little pain. Pain was most commonly perceived in the peripatellar area (25 patients (83%)). The most common site of pain on clinical examination was the peripatellar area (25 patients (83%)), but other synovial covered structures including the fat pad of Hoffa (12 patients (40%)), the medial plica and the joint line (12 patients (40%)) were also involved. Only eight patients (27%) experienced pain on the patellofemoral compression test. Only discrete changes was detected on MRI/ultrasound. Conclusions: Acute anterior knee pain should be regarded as a subgroup of PFPS as both symptoms and clinical examination suggests this. The clinical examination with disseminated pain in all synovial covered structures is consistent with ideas of the importance of synovium in the genesis of pain Udgivelsesdato: 2008/1

  17. MRI features of myositis ossificans with X-ray and CT findings

    International Nuclear Information System (INIS)

    Objective: To investigate the MRI features of myositis ossificans, and to address the correlation with X-ray radiography and CT findings. Methods: X-ray films, CT and MRI of 36 documented cases of myositis ossificans were retrospectively analyzed, and the literatures were reviewed. Results: Of the 36 cases, 4 cases occurred in the elbow joint, 4 in the shoulder joint, 15 in the hip joint, 6 in the tibiofibula, 5 in the femur, 1 in the metatarsal bones, and 1 in the ilium, respectively. Irregular patchy or lamellar high density calcification or ossification could be seen in the soft tissue parenchym on X-ray films and CT scan. Cortical bone integrity was preserved in diaphysis. CT enhanced scan showed that the swollen parenchyma was not enhanced and there was no parenchyma mass. On the early and middle stages, MR T1WI and T2WI showed slice-shaped low signal in the peripheral parenchyma, but patchy high signal was found around the low signal on T2WI. STIR showed mixed high and low signals in the swollen parenchyma with unclear demarcation. The lesions showed low signal on MR T1WI and T2WI in the late stage, and there was no edema in peripheral parenehyma. MRI enhanced scan found that the swollen parenchyma showed no enhancement in all stages. Conclusions: The imaging features of myositis ossificans have some characteristics. Misdiagnosis could be avoided when the disease was evaluated with the course. (authors)

  18. Serial MRI and MRS studies with unusual findings in Rasmussen's encephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Tuerkdogan-Soezueer, D. [Department of Pediatric Neurology, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Oezek, M.M.; Pamir, M.N. [Department of Neurosurgery, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Sav, A. [Department of Pathology, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Dincer, A. [Radyomar MR Center, Istanbul (Turkey)

    2000-06-01

    Rasmussen's syndrome is characterized by intractable seizures and progressive neuropsychiatric deterioration secondary to unilateral cortical inflammation and tissue destruction. Diagnosis of Rasmussen's syndrome in the early phase depends mainly on the clinical features. Neuroimaging and histopathologic examinations may not be specific during this period. We report a case of Rasmussen's syndrome followed by serial MRI and magnetic resonance spectroscopy (MRS) studies over a 3- to 16-month period. A healthy 6-year-old boy presented with focal motor seizures. An MRI study demonstrated prominent enlargement and T2 hyperintensity of the left mesial temporal lobe and perisylvian region. This early finding evolved to volume loss and later progressive atrophy of the ipsilateral hemisphere when epilepsia partialis continua occurred. Being aware of those early MRI features in a patient with increasing frequency of focal motor seizures should suggest Rasmussen's syndrome. In addition, we found prominently increased myoinositol concentration in atrophic cortex which might reflect increased gliosis in the late period of the disease. (orig.)

  19. Comparison of MRI and X-ray CT scan findings in serious head injury

    International Nuclear Information System (INIS)

    Twenty one patients with serious neurological deficits, prolonged consciousness disturbance and three months follow-up periods were examined by MRI at the acute to chronic stage, which were compared with X-ray CT findings. Sixteen patients' glasgow coma scale (GCS) on admission was less than 7, and five patients' GCS was more than 8. X-ray CT scan revealed diffuse brain contusion and/or hematoma in 14 patients, deep structural lesions in two patients and no lesion in five patients. MRI demonstrated cerebral contusion in 11 patients, deep structural lesions with or without cerebral contusion in 10 patients and no lesion in two patients. The deep structural lesions correlated with prolonged consciousness disturbance and serious neurological deficits, but did not closely related with clinical outcomes. These results indicated that X-ray CT scan was very effective for detecting the intracranial hemorrhagic lesions in the acute stage, but MRI was recommended for documenting brain lesions at the deep structures and evaluating the clinical outcomes in the chronic stage. (author)

  20. Little Leaguer's shoulder (proximal humeral epiphysiolysis): MRI findings in four boys

    Energy Technology Data Exchange (ETDEWEB)

    Obembe, Olufolajimi O.; Gaskin, Cree M.; Anderson, Mark W. [UVA Health Sciences Center, Department of Radiology, P.O. Box 800170, Charlottesville, VA (United States); Taffoni, Matthew J. [Piedmont Radiological Associates, Salisbury, NC (United States)

    2007-09-15

    Shoulder pain is a common problem among adolescent athletes. A possible cause of such pain that can be diagnosed on MRI is a stress injury to the proximal humerus known as Little Leaguer's shoulder (proximal humeral epiphysiolysis). Our objective was to describe the MRI appearance of Little Leaguer's shoulder. Four patients (all boys; age range 11-15 years; median 13 years) with clinical, plain radiographic, and MR imaging findings of Little Leaguer's shoulder were studied retrospectively. MRI demonstrated focal physeal widening in all four boys with extension of physeal signal intensity into the metaphysis on T1-weighted and gradient echo coronal and sagittal sequences. T2-weighted sequences were of limited use in demonstrating the physeal widening, which is critical to the diagnosis. Abnormal high T2-signal intensity was seen in the metaphysis adjacent to the focal physeal widening in all the boys. Focal extension of normal physeal T1-weighted and gradient echo signal intensity into the adjacent metaphysis is a sign of stress injury in the proximal humeral physis (Little Leaguer's shoulder). Children should suspend the offending sport to allow healing. (orig.)

  1. Do positive MRI findings in the lumbar spine predict future seeking care for low back pain in young teenagers?

    DEFF Research Database (Denmark)

    Kjær, Per; Leboeuf-Yde, Charlotte; Korsholm, Lars; Wedderkopp, Niels; Bendix, Tom

    2011-01-01

    Background: In MRI studies lumbar disk degeneration and endplate changes have been found in children and adolescents. Such MRI findings appear to be more strongly associated with LBP than in adults. However, this knowledge is mainly based on cross-sectional studies from which no inferences regarded causality can be drawn. The purpose of this presentation is to show how certain MRI findings at the age of 13 indicate seeking care for LBP at the age of 16. Methods: In a population based longitudina...

  2. Atrial myxoma demonstrated by cine gradient refocused echo magnetic resonance imaging

    International Nuclear Information System (INIS)

    A case of atrial myxoma presenting with syncope evaluated by echocardiography(ECG) and MRI is described. Cine gradient-echo gadolinium-DTPA enhanced MRI demonstrated atrial myxoma as a very low signal intensity mass indicating the presence of haemosiderin. Although ECG is a sensitive method for the diagnosis of intracardiac tumours, the MRI offered an alternative imaging modality, in multiple planes, delineated the tumour and provided complimentary information to ECG. Copyright (1999) Blackwell Science Pty Ltd

  3. Herpes simplex encephalitis: MRI findings in two cases confirmed by polymerase chain reaction assay

    International Nuclear Information System (INIS)

    Herpes simplex virus (HSV) type I causes a fulminant necrotising meningoencephalitis distinguished from other encephalitides by its focal and often haemorrhagic nature. Specific antiviral therapy with acyclovir can significantly improve the prognosis. We present MRI findings of two cases of herpes simplex encephalitis (HSE) confirmed by PCR analysis, focusing on the serial changes after acyclovir therapy: gyral swelling, high signal intensity on T2-weighted images in the subfrontal region, temporal lobe and insula in the initial stage, then regional extension with enhancement and haemorrhage despite appropriate acyclovir therapy, and finally encephalomalacia and brain atrophy. (orig.)

  4. Herpes simplex encephalitis: MRI findings in two cases confirmed by polymerase chain reaction assay

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J.W.; Kim, I.O.; Kim, W.S.; Yeon, K.M. [Dept. of Radiology and the Institute of Radiation Medicine, Seoul National University Hospital, Seoul (Korea); Lee, H.-J.; Hwang, Y.S. [Dept. of Paediatrics, Seoul National University College of Medicine, Seoul (Korea)

    2001-09-01

    Herpes simplex virus (HSV) type I causes a fulminant necrotising meningoencephalitis distinguished from other encephalitides by its focal and often haemorrhagic nature. Specific antiviral therapy with acyclovir can significantly improve the prognosis. We present MRI findings of two cases of herpes simplex encephalitis (HSE) confirmed by PCR analysis, focusing on the serial changes after acyclovir therapy: gyral swelling, high signal intensity on T2-weighted images in the subfrontal region, temporal lobe and insula in the initial stage, then regional extension with enhancement and haemorrhage despite appropriate acyclovir therapy, and finally encephalomalacia and brain atrophy. (orig.)

  5. Labyrinthitis ossificans in a child with sickle cell disease: CT and MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Benjamin P. [Boston University School of Medicine, Department of Radiology, Boston Medical Center, Boston, MA (United States); Northwestern University, Section of Neuroradiology, Feinberg School of Medicine, Chicago, IL (United States); Saito, Naoko; Wang, Jimmy J.; Mian, Asim Z.; Sakai, Osamu [Boston University School of Medicine, Department of Radiology, Boston Medical Center, Boston, MA (United States)

    2009-09-15

    The association between sensorineural hearing loss and sickle cell disease has been described, and labyrinthine hemorrhage has been reported with sickle cell disease. We report the CT and MRI findings of labyrinthitis ossificans in a child with sickle cell disease who presented with sensorineural hearing loss. Labyrinthitis ossificans is associated with an infectious, inflammatory, or destructive insult to the membranous labyrinth; however, it has not been specifically described with sickle cell disease. Recognition of this condition is important because it affects both management and prognosis of this disease. (orig.)

  6. Labyrinthitis ossificans in a child with sickle cell disease: CT and MRI findings

    International Nuclear Information System (INIS)

    The association between sensorineural hearing loss and sickle cell disease has been described, and labyrinthine hemorrhage has been reported with sickle cell disease. We report the CT and MRI findings of labyrinthitis ossificans in a child with sickle cell disease who presented with sensorineural hearing loss. Labyrinthitis ossificans is associated with an infectious, inflammatory, or destructive insult to the membranous labyrinth; however, it has not been specifically described with sickle cell disease. Recognition of this condition is important because it affects both management and prognosis of this disease. (orig.)

  7. Spinal Cord Glioblastoma Induced by Radiation Therapy of Nasopharyngeal Rhabdomyosarcoma with MRI Findings: Case Report

    International Nuclear Information System (INIS)

    Radiation-induced spinal cord gliomas are extremely rare. Since the first case was reported in 1980, only six additional cases have been reported.; The radiation-induced gliomas were related to the treatment of Hodgkin's lymphoma, thyroid cancer, and medullomyoblastoma, and to multiple chest fluoroscopic examinations in pulmonary tuberculosis patient. We report a case of radiation-induced spinal cord glioblastoma developed in a 17-year-old girl after a 13-year latency period following radiotherapy for nasopharyngeal rhabdomyosarcoma. MRI findings of our case are described.

  8. Spinal Cord Glioblastoma Induced by Radiation Therapy of Nasopharyngeal Rhabdomyosarcoma with MRI Findings: Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Se Jin; Kim, In One [Dept. of Radiology, Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2012-09-15

    Radiation-induced spinal cord gliomas are extremely rare. Since the first case was reported in 1980, only six additional cases have been reported.; The radiation-induced gliomas were related to the treatment of Hodgkin's lymphoma, thyroid cancer, and medullomyoblastoma, and to multiple chest fluoroscopic examinations in pulmonary tuberculosis patient. We report a case of radiation-induced spinal cord glioblastoma developed in a 17-year-old girl after a 13-year latency period following radiotherapy for nasopharyngeal rhabdomyosarcoma. MRI findings of our case are described.

  9. Syringomyelia: Correlation between MRI and clinical findings before and after surgery

    International Nuclear Information System (INIS)

    A comparison between clinical and MRI findings in 20 patients with syringomyelia produced the following results: 1. The position and extent of the syrinx do not correspond with the clinical findings. 2. Successfully operated syringomyelia cavities collapse in their sagittal diameters. The resulting oval shape of the syrinx can be used to evaluate shunt insufficiency. 3. In almost half of the patients the diameter of the spinal cord is within the 95% of normal controls and would therefore not have been diagnosed by myelography. 4. Anomalies of the cranio-cervical junction were present in only one-third of the patients. This finding does not support the hypothesis that syringomyelia is caused by hydrodynamic factors only. (orig.)

  10. MRI findings of the wrist in patients with multiple osteonecrosis in large joints of the extremities

    International Nuclear Information System (INIS)

    We evaluated MRI findings of the wrist in patients who had multiple osteonecrosis in the large joints of their extremities (hips, knees, shoulders, and ankles) and compared these with the clinical symptoms and radiographical findings. Sixty wrists of 30 patients (3 males and 27 females) with multiple osteonecrosis were studied. Subjects ranged in age from 16 to 59 years. Their primary diseases were SLE in 24 patients, alcoholic osteonecrosis in two, Sjoegren's syndrome in one, dermatomyositis in one, leukemia in one, and MCTD in one patient. Using MRI, we found osteonecrosis in seven wrists of four patients. Lesions were seen in six scaphoids of three patients, in two lunates of two patients, and in one capitate. We noted a reduced range of motion in three of the seven wrists with osteonecrosis. Two of the seven complained at wrist pain at motion, although three wrists were symptom free. Radiographically, an abnormality was recognized in two of the seven wrists. Generally, osteonecrosis of the lunate (Kienboeck's disease) is more frequent than that of the scaphoid (Preiser's disease). However in the present series, we found a higher osteonecrosis rate of the scaphoid than the lunate, using MRI. The discrepancy can be explained by the vascularity. In 1986, Gelberman reported that the scaphoid, the capitate, and 8% of the lunate had either vessels entering only one surface or large areas of bone that were dependent on a single vessel. The present study is consistent with these anatomical features. In other words, the present results demonstrated that Kienboeck's disease can be induced not only by a deficient blood supply but also by some additional factors. (author)

  11. CT and MRI findings of temporal bone anomaly in patients with tinnitus

    International Nuclear Information System (INIS)

    Objective: To study high resolution CT (HRCT) and MRI findings of temporal hone anomaly in patients with tinnitus and identify the optimal examination method in the detection of the anomaly. Methods: The HRCT and MRI data were analyzed retrospectively in 1015 patients including 145 patients with pulsatile tinnitus (PT) and 870 patients with nonpulsatile tinnitus (NPT). The positive rates of HRCT and MRI in the identification of temporal bone anomaly were analyzed and the efficiency of various examination methods was compared in revealing the anomaly. Data were tested by Chi-square test analysis. Results: Among 1015 patients, anomaly was seen in 767 cases (75.57%). High jugular bulb was found in 414 patients, accounting for 40.79%. Sigmoid sinus anomaly was detected in 387 patients (38.13%), while otitis media was found in 148 cases (14.58%), and low middle cranial fossa in 70 cases (6.90%). The positive rate of HRCT in the detection of high jugular bulb was 54.89% (365/665), which was significantly higher than those of other methods (P2=56.537, P<0.01). The fast imaging employing steady-state acquisition (FIESTA) sequence was the best examination method in displaying the vessel within the internal auditory canal (42/42,100%). Conclusions: High jugular bulb and sigmoid sinus anomaly were the most frequent abnormal findings of temporal bone in patients with tinnitus. Enhanced HRCT was the choice of modality in patients with PT. Plain HRCT was recommended for NPT. FIESTA sequence was the best in the evaluation of the vessel within the internal auditory canal. (authors)

  12. MRI findings before and after abdominal radical trachelectomy (ART) for cervical cancer: A prospective study and review of the literature

    International Nuclear Information System (INIS)

    Aim: To report the authors' experience with dedicated pelvic magnetic resonance imaging (MRI) in young women with early-stage cervical cancer treated with abdominal radical trachelectomy (ART). Materials and methods: During a 5-year period, 21 patients, with biopsy-confirmed cervical carcinoma, International Federation of Gynaecology and Obstetrics (FIGO) stage ?IB1, were considered for trachelectomy. All patients underwent pelvic MRI within 30 days prior to surgery. Tumour size, endocervical extension, extrauterine spread, and nodal status were noted. Postoperative MRI findings were reviewed in 16 patients. Results: Nineteen of the 21 patients were treated with ART. In two patients, trachelectomy was aborted intraoperatively and radical hysterectomy was performed; preoperative MRI findings were consistent with surgicopathological examination in both patients. MRI correctly assessed tumour size in 18/21 patients, coming within 5 mm of the surgical specimen. Tumour size was underestimated in two cases because of circumferential growth (n = 1) or technical difficulties (n = 1). False-positive MRI result was due to post-biopsy inflammation (n = 1). MRI accurately identified absence of internal os involvement in 17/19 ART patients; false-positive MRI for internal os involvement were due to endocervical polyp (n = 1) and coexisting Nabothian cysts (n = 1). No trachelectomy patient had extrauterine disease or malignant nodes at MRI or final histology. Post-trachelectomy complications included hydrosalpinges (n = 3), lymphocysts (n = 2), isthmic stenosis (n = 1), and tumour relapse (n = 2). Conclusions: Dedicated pelvic MRI is helpful in assessing tumour size and endocervical extension in young women, candidates for ART. Hydrosalpinx may occur after ART and it may influence fertility potential

  13. Cine-Club

    CERN Multimedia

    Cine-Club

    2013-01-01

    The CERN CineClub is a meeting point every Thursday for anyone who wants to discover, discuss, and appreciate cinema with people who are truly interested in the art of the moving image. In the actual context where downloading became easier than cooking an egg, one might wonder why bother when it can be watched on any computer. Well, cinema is not an individual activity. What the CineClub offers is a big screen with good quality image and sound. It also offers a careful selection, for allowing people to (re-)discover new and forgotten authors. Finally, it offers the opportunity for meeting people sharing a common interest. So come every Thursday, and see by yourself that watching films can actually be a real party! Every Thursday at 20 h 00 Council Chamber, 503/1-001 Programme June 2013 Science Fiction Cycle “Imagination is more important than knowledge. For knowledge is limited, whereas imagination embraces the entire world, stimulating progress, giving birth to evolution.” 6th June 2...

  14. Cine MR imaging

    International Nuclear Information System (INIS)

    Limited-flip-angle gradient-recalled imaging coupled with cardiac gating (cine magnetic resonance [MR] imaging) has added to the potential advantages of MR imaging for cardiovascular diagnosis by enabling improved temporal resolution as well as high spatial and contrast resolution. Four hundred fifteen patients were examined with a 1.5-T General Electric Signa unit. The examinations were performed with a repetition time of 21 msec, an echo time of 13 msec, and a theta of 300. Nine contiguous sections were obtained in three acquisitions of 256 heartbeats each. Each acquisition ranged from 2.5 to 6 minutes. Patient ages ranged from 1 month to 86 years. Patients included 19 with chronic coronary disease, 51 with acute myocardial infarction, 28 with aortic dissection, 27 with pulmonary artery abnormalities, 83 with valvular disease, 49 with cardiomyopathies, 40 with pericardial disease, 29 with tumors, and 33 with congenital heart disease. The cine technique was useful in areas where functional information was necessary. Ejection fractions, volumes, and mass measurements were obtained. The improved temporal, contrast, and spatial resolution aided in the diagnosis of most cardiac pathologies

  15. CT, MRI, and FDG-PET/CT imaging findings of abdominopelvic desmoplastic small round cell tumors: Correlation with histopathologic findings

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Weidong, E-mail: dongw.z@163.com [State Key Laboratory of Oncology in South China, 651 Dongfengdong Road, Guangzhou, Guangdong 510060 (China) and Department of Radiology, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong 510060 (China); Li Chuanxing, E-mail: lichuanh@mail.sysu.edu.cn [State Key Laboratory of Oncology in South China, 651 Dongfengdong Road, Guangzhou, Guangdong 510060 (China); Department of Radiology, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong 510060 (China); Liu Qingyu, E-mail: liu.qingyu@163.com [Department of Radiology, No. 2 Affiliated Hospital, 107 Yanjiangxi Road, Sun Yat-sen University, Guangzhou, Guangdong 510120 (China); Hu Yingying, E-mail: yingyinghu1981@163.com [State Key Laboratory of Oncology in South China, 651 Dongfengdong Road, Guangzhou, Guangdong 510060 (China) and Department of Radiology, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong 510060 (China); Cao Yun, E-mail: caoyun@mail.sysu.edu.cn [State Key Laboratory of Oncology in South China, 651 Dongfengdong Road, Guangzhou, Guangdong 510060 (China); Department of Pathology, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong 510060 (China); Huang Jinhua, E-mail: drhuangjh@163.com [State Key Laboratory of Oncology in South China, 651 Dongfengdong Road, Guangzhou, Guangdong 510060 (China) and Department of Radiology, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong 510060 (China)

    2011-11-15

    Objective: To analyze computed tomography (CT), magnetic resonance imaging (MRI), and fluorodeoxyglucose-positron emission tomography (FDG-PET)/CT imaging features of abdominopelvic desmoplastic small round cell tumor (DSRCT) and to improve the diagnostic efficacy of these techniques for the detection of such tumor. Methods: We retrospectively analyzed 7 cases of abdominopelvic DSRCT confirmed by histopathologic analysis. Among the 7 patients, 5 patients had undergone CT scanning, 2 of which were also examined with FDG-PET/CT imaging, and 2 had undergone MRI. Unenhanced and contrast-enhanced examinations were performed in all patients, and 2 patients had also undergone dynamic CT contrast-enhanced examinations. Image characteristics, such as shape, size, number, edge, attenuation, and intensity of each lesion before and after contrast enhancement were analyzed and compared with the pathomorphology of the tumors. Results: Multiple large masses in the abdominopelvis were detected in 6 cases, and a large mass in the pelvis was detected in 1 case. Six cases showed largest mass in pelvis, and 1 case in mesentery. None of the masses had a definite organ origin. CT showed soft tissue masses with patchy foci of hypodense areas. MR T1-weighted images revealed lesions with mild hypointense areas and patchy hypointense areas in 2 cases and lesions with patchy hyperintense areas in 1 case. T2-weighted images showed lesions with mixed isointense and hyperintense areas in 1 case and lesions with mixed hypointense, isointense, and hyperintense areas in another. Contrast-enhanced CT and T1-weighted images showed mildly heterogeneous enhancement of the lesions. Other associated findings included peritoneal seeding (n = 3), peritoneal effusions (n = 3), hepatic metastasis (n = 2), bone metastasis (n = 1), and mesenteric and retroperitoneal lymphadenopathy (n = 4). FDG-PET/CT showed multiple nodular foci of increased metabolic activity in the abdominopelvic masses, in the hepatic and right ilium in 1 case and foci of increased metabolic activity in the pelvic mass in another. Conclusion: Radiological findings of DSRCT include multiple masses with heterogeneous density/intensity and without an organ origin. Other common associated findings include peritoneal seeding, peritoneal effusion, hepatic metastasis, and retroperitoneal lymphadenopathy. DSRCT should be considered in the differential diagnosis of regional tumors in adolescents and young adults. FDG-PET/CT can provide additional information on the stage of the tumor.

  16. Unicompartmental knee arthroplasty MRI: impact of slice-encoding for metal artefact correction MRI on image quality, findings and therapy decision

    Energy Technology Data Exchange (ETDEWEB)

    Agten, Christoph A.; Pfirrmann, Christian W.A.; Sutter, Reto [Balgrist University Hospital, Radiology Department, Zurich (Switzerland); University of Zurich, Faculty of Medicine, Zurich (Switzerland); Grande, Filippo del [Regional Hospital, Radiology, Lugano (Switzerland); Fucentese, Sandro F.; Blatter, Samuel [University of Zurich, Faculty of Medicine, Zurich (Switzerland); Balgrist University Hospital, Orthopedics, Zurich (Switzerland)

    2015-07-15

    To evaluate the impact of slice-encoding for metal artefact correction (SEMAC) on image quality, findings, and therapy decision in patients with unicompartmental knee arthroplasty (UKA). Forty-five painful UKAs were examined at 1.5T-MRI (STIR, proton-density(PD)-weighted sequence, each with SEMAC and high-bandwidth). Artefact size, image quality, anatomic depiction, and clinically relevant findings were compared between SEMAC and high-bandwidth (2 readers). In 30 patients, therapy decision was retrospectively assessed by two orthopaedic surgeons without MRI, with high-bandwidth-MRI, and with SEMAC-MRI. SEMAC reduced mean artefact size for STIR (11.8 cm{sup 2} vs. 37.7 cm{sup 2}) and PD (16.8 cm{sup 2} vs. 18.9 cm{sup 2}), p < 0.0005 for both comparisons. SEMAC showed more blurring than high-bandwidth, p < 0.0005. STIR-SEMAC revealed more bone marrow oedema (29 vs. 18 patients, p = 0.001, 30 vs. 13 patients, p < 0.0005, for reader 1 and 2 respectively). PD-SEMAC was worse in detecting meniscal lesions (6 missed, p = 0.031, 9 missed, p = 0.004, by reader 1 and 2 respectively) than PD-high-bandwidth. Revision-surgery was chosen in 12 and 11 patients without MRI (surgeon 1 and 2), with high-bandwidth-MRI in 15 and 14 patients, and with SEMAC-MRI in 19 and 14 patients. STIR-SEMAC was useful in detecting bone marrow oedema and influenced the orthopaedic surgeons' decisions towards surgery, while PD-SEMAC showed no clinical benefit. (orig.)

  17. Unicompartmental knee arthroplasty MRI: impact of slice-encoding for metal artefact correction MRI on image quality, findings and therapy decision

    International Nuclear Information System (INIS)

    To evaluate the impact of slice-encoding for metal artefact correction (SEMAC) on image quality, findings, and therapy decision in patients with unicompartmental knee arthroplasty (UKA). Forty-five painful UKAs were examined at 1.5T-MRI (STIR, proton-density(PD)-weighted sequence, each with SEMAC and high-bandwidth). Artefact size, image quality, anatomic depiction, and clinically relevant findings were compared between SEMAC and high-bandwidth (2 readers). In 30 patients, therapy decision was retrospectively assessed by two orthopaedic surgeons without MRI, with high-bandwidth-MRI, and with SEMAC-MRI. SEMAC reduced mean artefact size for STIR (11.8 cm2 vs. 37.7 cm2) and PD (16.8 cm2 vs. 18.9 cm2), p < 0.0005 for both comparisons. SEMAC showed more blurring than high-bandwidth, p < 0.0005. STIR-SEMAC revealed more bone marrow oedema (29 vs. 18 patients, p = 0.001, 30 vs. 13 patients, p < 0.0005, for reader 1 and 2 respectively). PD-SEMAC was worse in detecting meniscal lesions (6 missed, p = 0.031, 9 missed, p = 0.004, by reader 1 and 2 respectively) than PD-high-bandwidth. Revision-surgery was chosen in 12 and 11 patients without MRI (surgeon 1 and 2), with high-bandwidth-MRI in 15 and 14 patients, and with SEMAC-MRI in 19 and 14 patients. STIR-SEMAC was useful in detecting bone marrow oedema and influenced the orthopaedic surgeons' decisions towards surgery, while PD-SEMAC showed no clinical benefit. (orig.)

  18. Chronic exertional compartment syndrome of the forearm in motocross racers: findings on MRI

    International Nuclear Information System (INIS)

    The purpose of this prospective study was to demonstrate the findings of MRI in motocross racers with chronic exertional compartment syndrome (CECS) of the forearm. Racers with proven CECS and without CECS and male individuals not involved in strenuous activities with the forearm were included. Signal intensity (SI) and signal-to-noise ratio (SNR) obtained before and after exercise were compared (D-SNR). Magnetic resonance imaging after exercise showed an increase in SI and SNR in the muscles on T2-WI. The SI increase was obvious in the flexor digitorum superficialis (FDS) and profundus (FDP) in all CECS patients. In addition, a minor SI and SNR increase in the extensor carpi radialis longus (ECRL) was noted. In the non-symptomatic group of motocross racers, there was only a minor increase in SI and the SNR, which was similar in the FDP and ECRL muscles. In the untrained individuals a remarkable increase in the SI and SNR of the FDS/FDP-ECRL was noted. This increased SI and SNR was not present in the majority of non-symptomatic racers. Post-exertional MRI produces significant findings in CECS of the forearm. The motocross racers without post-exertional oedema in the FDP/FDS had no CECS. (orig.)

  19. Chronic exertional compartment syndrome of the forearm in motocross racers: findings on MRI

    Energy Technology Data Exchange (ETDEWEB)

    Gielen, Jan Louis [Antwerp University Hospital, Department of Radiology, Antwerp (Belgium); Antwerp University Hospital, Multidisciplinary Department of Sports Medicine, Antwerp (Belgium); Peersman, Benjamin; Dyck, Pieter van; Vanhoenacker, Filip [Antwerp University Hospital, Department of Radiology, Antwerp (Belgium); Peersman, Geert [ZNA, Department of Orthopaedic Surgery, Antwerp (Belgium); Roelant, Ella [Antwerp University Hospital, Department of Scientific Coordination, Antwerp (Belgium); Roeykens, Johan [Antwerp University Hospital, Multidisciplinary Department of Sports Medicine, Antwerp (Belgium)

    2009-12-15

    The purpose of this prospective study was to demonstrate the findings of MRI in motocross racers with chronic exertional compartment syndrome (CECS) of the forearm. Racers with proven CECS and without CECS and male individuals not involved in strenuous activities with the forearm were included. Signal intensity (SI) and signal-to-noise ratio (SNR) obtained before and after exercise were compared (D-SNR). Magnetic resonance imaging after exercise showed an increase in SI and SNR in the muscles on T2-WI. The SI increase was obvious in the flexor digitorum superficialis (FDS) and profundus (FDP) in all CECS patients. In addition, a minor SI and SNR increase in the extensor carpi radialis longus (ECRL) was noted. In the non-symptomatic group of motocross racers, there was only a minor increase in SI and the SNR, which was similar in the FDP and ECRL muscles. In the untrained individuals a remarkable increase in the SI and SNR of the FDS/FDP-ECRL was noted. This increased SI and SNR was not present in the majority of non-symptomatic racers. Post-exertional MRI produces significant findings in CECS of the forearm. The motocross racers without post-exertional oedema in the FDP/FDS had no CECS. (orig.)

  20. MRI findings of cerebral parenchyma along a ventricular catheter under various intracranial conditions

    International Nuclear Information System (INIS)

    We have experienced 4 cases of cerebral parenchymas in which high intensity was sustained by MRI T2 WI, though a low density disappeared in CT, among the cases in which an expansion of the low density was observed in the cerebral parenchyma along a ventricular catheter by a CT scan after ventricular drainage and a shunt operation designed to combat increased intracranial pressure due to meningitis and a brain tumor. The cases were classified on the basis of morbidity into 1 case of cryptococcus meningitis, 1 case complicated by cerebellar hemorrhage and meningitis, and two cases of acute increased intracranial pressue due to a thalamic tumor and cerebellar astrocytoma. If a ventricular catheter or drainage tube is inserted, cerebral fluid penetrates into the cerebral parenchyma to cause a change in the tissue which can be explained, on the basis of CT findings, as a reversible change. However, this histological change is not always reversible according to our present MRI finding; rather, it becomes strong if the results of an inflammation such as meningitis are added to the cerebral fluid; in such a case, the reversibility is considered to disappear completely. (author)

  1. MRI findings of cerebral parenchyma along a ventricular catheter under various intracranial conditions

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, Yoshisuke; Hoshino, Tamotsu; Suzuki, Hidenori (Matsusaka Chuo Hospital, Mie (Japan))

    1993-12-01

    We have experienced 4 cases of cerebral parenchymas in which high intensity was sustained by MRI T[sub 2] WI, though a low density disappeared in CT, among the cases in which an expansion of the low density was observed in the cerebral parenchyma along a ventricular catheter by a CT scan after ventricular drainage and a shunt operation designed to combat increased intracranial pressure due to meningitis and a brain tumor. The cases were classified on the basis of morbidity into 1 case of cryptococcus meningitis, 1 case complicated by cerebellar hemorrhage and meningitis, and two cases of acute increased intracranial pressue due to a thalamic tumor and cerebellar astrocytoma. If a ventricular catheter or drainage tube is inserted, cerebral fluid penetrates into the cerebral parenchyma to cause a change in the tissue which can be explained, on the basis of CT findings, as a reversible change. However, this histological change is not always reversible according to our present MRI finding; rather, it becomes strong if the results of an inflammation such as meningitis are added to the cerebral fluid; in such a case, the reversibility is considered to disappear completely. (author).

  2. MRI findings of neurologic complications in the enterovirus 71-infected hand-foot-mouth disease

    International Nuclear Information System (INIS)

    Objective: To explore the imaging characteristics of neurologic complications associated with the enterovirus 71 (EV71) epidemic by analyzing 25 cases and reviewing the literature. Methods: Twenty-five cases of hand-foot-mouth disease with neurologic complications during the recent EV71 outbreaks of Hainan province were studied for the clinical features and imaging findings, and literature were reviewed. Results: In 5 cases, acute flaccid paralysis associated with EV71-infected hand-foot-mouth disease was related to the linear high signal in the spinal cord on sagittal images. Two cases showed symmetrical, well- defined hyperintense lesions in the spinal cord on T2WI transverse. Strong enhancement of the ventral horns and root was seen on the contrast-enhanced axial T1WI. In brainstem encephalitis, all lesions presented with significant hyperintensity on T2WI and hypointense on T1WI in the posterior portions of the medulla oblongata, midbrain, and pons. The manifestations of aseptic meningitis (AM) on MRI have no characteristics, but subdural effusion, meningeal enhancement and hydrocephalus can be the indirect signs of AM. Conclusions: MRI is an effective method to investigate neurologic complications associated with the EV71 epidemic. Posterior portions of the medulla oblongata and pons, bilateral ventral horns of spinal involvement are characteristic findings of enteroviral encephalomyelitis. (authors)

  3. Recurrent back pain after diskectomy: MRI findings MR of the postoperative lumbar spine

    International Nuclear Information System (INIS)

    Purpose: To show the morphological changes in postoperative lumbar spine. Material and methods: We reviewed 128 Magnetic Resonance Imaging (MRI) studies of lumbar spine. All patients complained of low back pain and had a previous lumbar surgery (1 month to 8 years). All the examinations include axial and sagittal Gadopentate-dimeglumine enhanced T1 weighted imaging. Results: Only 7,8% have the normal appearance of the postoperative lumbar spine. Epidural scar was found in 69% of examinations; of this group, 72% showed radicular involvement, and 28% had no radicular involvement. Recurrent disc herniation was found in 14,8% of exams, using gadopentate-dimeglumine to assist the differentiation from epidural fibrosis; infections like spondylodiscitis and abscess in 12,5%. Other findings included arachnoiditis, pseudomeningoceles and seromas. Conclusions: MRI is a useful method to study the postoperative lumbar spine, specially when enhanced with gadopentate-dimeglumine. Enhanced images can differentiate two of the major complication like epidural fibrosis, and recurrent disc herniation. Spondylodiscitis are important and frequent too. Although the findings of complications in our series in the postoperative lumbar spine represent 92,18 %, these not always explain the symptomatology. Therefore, the interrelation is important with the surgeon to determine which abnormalities are clinically significant. (authors)

  4. CT and MRI findings in KIT-weak or KIT-negative atypical gastrointestinal stromal tumors

    International Nuclear Information System (INIS)

    The large majority of gastrointestinal stromal tumors (GIST) can be diagnosed on the basis of KIT immunoreactivity. However, some atypical tumors show weak or negative KIT expression. We studied the imaging characteristics of atypical GIST, reviewing CT and MRI findings in ten patients (eight men, two women; mean age 59 years) with atypical GIST. Radiological studies were evaluated by two radiologists by consensus and included CT and MR imaging in all patients. Pathological diagnoses were made from surgery and confirmed by the polymerase-chain reaction (PCR) to amplify both exons of the c-kit gene and PDGFRA gene. The CT and MR examinations revealed a heterogeneous mass of the stomach containing cystic regions and soft tissue elements in all cases. All lesions were extraluminal masses and had an exophytic epicenter. On T1-weighted MR images soft tissue elements of the tumors were of homogeneously low- (n=3) or iso-signal intensity (n=7) compared with the liver parenchyma. On fast spin-echo T2-weighted MR images soft tissue elements of all tumors showed cystic regions of significantly high signal intensity interspersed with septumlike structures of low signal intensity. All lesions exhibited homogeneously (n=4) or heterogeneously (n=6) mild to moderate enhancement of soft tissue elements. Despite the relatively small number of patients CT and MRI findings of atypical GIST are a submucosal mass with soft tissue elements and cystic regions. (orig.)

  5. Partial achilles tendon rupture presenting with giant hematoma; MRI findings of 4 year follow up.

    Science.gov (United States)

    Sarsilmaz, Aysegul; Varer, Makbule; Coskun, Gulten; Apayd?n, Melda; Oyar, Orhan

    2011-12-01

    In the young population, spontaneous rupture of Achilles tendon is very rare. The big hematoma is also rare finding of the Achilles tendon partial rupture. It is usually seen with complete rupture. We presented imaging findings of 4 years follow up of the spontaneous partial rupture of Achilles tendon presenting with giant expanding hematoma and mimicking complete rupture radiologically. We discussed the alterations of tendon signal intensity and result of conservative therapy after partial rupture with big hematoma in the long term. A 29 year-old man, applied with pain and swelling in the retrocalcaneal region of left ankle. He did not have chronic metabolic disease. He was not active in physical activities. X-ray radiograms were normal. At magnetic resonance images (MRI), there was an intratendinous big hematoma, subcutanous fat planes were edematous around tendon. The diagnosis was partial rupture and giant hematoma. Hematoma was drained. The conservative treatment was applied and his complaints disappeared. After treatment, approximately 4 years later, control MRI showed thickened and hypointense tendon in all images. PMID:21856146

  6. Globus pallidus high-signal lesions: A predominant MRI finding in children with neurofibromatosis type 1

    Directory of Open Access Journals (Sweden)

    Arif Khan

    2013-01-01

    Full Text Available Introduction: Lesions of the brain, recognized as unidentified bright objects (UBOs, are commonly observed as areas of increased T2-weighted signal intensity on magnetic resonance imaging (MRI in children with neurofibromatosis type 1 (NF1. Identification of these lesions is not currently encompassed in the National Institute of Health (NIH diagnostic criteria for NF1. Objective: We aimed to determine the prevalence of UBOs in children with NF1 and identify areas of the brain that are commonly affected by these lesions, allowing us to evaluate whether UBOs should be included in the diagnostic criteria for the diagnosis of NF1. Materials and Methods: We reviewed the cranial MRI scans of 22 children who had been diagnosed with sporadic or familial NF1 in accordance with the criteria established by NIH. UBOs were present in 81% of the children with NF1. Results: These lesions have a predilection for specific areas of the brain, including the globus pallidus (72%, cerebellum (66%, brainstem (27% and cerebral hemispheres (16%. The prevalence of UBOs identified varied significantly with age and sex; they were infrequent in children less than 4 years of age but were common in those aged between 4 and 12 years of age. UBOs were more commonly seen in males (66.6% compared with females (33.3%. Repeat MRI scan on a subset of these patients with UBOs did not show any significant changes despite a worsening in clinical symptoms. Conclusion and Discussion: We have shown that UBOs are a common finding in children with NF1, and are most prevalent between the ages of 4 and 12 years. Many sites of the brain are affected by these lesions, most notably the globus pallidus and the cerebellum. Further research must be conducted to elucidate the significance of UBOs in patients with NF1 and whether these lesions have any utility in the clinical detection of NF1.

  7. A study on clinical findings about vertebral disease diagnosed with MRI

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ham-Gyum [Ansan College, Seoul (Korea, Republic of)

    2006-09-15

    In order to analyze clinical characteristics like sex-and age-based onset frequency and onset region from vertebral disease cases, this study investigated total 1,291 cases of vertebral disease that were diagnosed via magnetic resonance imaging (MRI) from January to December 2004 at B University Hospital in metropolitan area. For higher diagnostic accuracy in cases of spinal disorder diagnosed, this study analyzed findings from data reading conducted by veteran specialists in diagnostic radiology. But this study excluded uncertain lesion cases, the cases requiring differential diagnosis from other disorders and so on from subjects under analysis. This study employed superconductive 1.5 Tesla SIGNA MR/i for MRI test and basically received resulting images via FSE (fast spin echo). In particular, this study obtained T1 and T2 myelogram with regard to regional characteristics (such as cervical vertebrae, thoracic vertebrae and lumbar vertebra) and imaging characteristics for sagittal and transverse section. As a result, this study came to the following conclusions: 1. In terms of general characteristics of subjects under analysis, male group comprised 53.5% and female 46.5% out of total 1,291 subjects. 2. The regional onset frequency of spinal disorders was converged primarily on lumbar vertebra (65.5%), which was followed by cervical vertebrae (27.3%) and thoracic vertebrae (7.0%) respectively. 3. Top 10 cases with high onset frequency of spinal disorders can be listed as follows: 1) posterior bulging disc 65.8% 2) narrowing of neural foramen 23.8% 3) herniated intervertebral disc (HIVD) 22.4% 4) spinal stenosis 16.7% 5) osteochondrosis 6.4% 6) compression fracture 6.4% 7) facet joint arthropathy 6.2% 8) spondylolisthesis 6.0% 9) spinal cord tumor 3.5% 10) inter body fusion 2.6%.

  8. Liver and spleen MRI findings in virus-associated hemophagocytic syndrome in a patient with acute lymphocytic leukemia

    International Nuclear Information System (INIS)

    Virus-associated hemophagocytic syndrome is characterized by the phagocytosis of erthythrocytes and other blood elements in multiple organ systems, especially the liver and spleen. Magnetic resonance imaging (MRI) can suggest this diagnosis in the proper clinical setting by demonstrating multiple, rounded signal voids in the spleen corresponding to hemosiderin deposition. We report a patient with virus-associated hemophagocytic syndrome during the course of acute lymphocytic leukemia and MRI findings that suggested the preoperative diagnosis. (orig.)

  9. CT and MRI findings of central nervous system complications of leukemia

    International Nuclear Information System (INIS)

    Objective: To evaluate the CT and MRI findings and their diagnostic value of central nervous system complications of leukemia (CNSCL). Methods: The CT and MRI findings of 18 adult patients with CNSCL proved by clinical features or pathology were retrospectively analyzed. Among 18 cases, 7 were acute lymphocytic leukemia, 10 acute non-lymphocytic leukemia and 1 chronic myelomonocytic leukemia. Eleven cases underwent plain CT scan with one of them also receiving contrast-enhanced CT scan enhancement, 16 cases underwent plain MR scan with 11 of them receiving contrast-enhanced MR scan. Results: Intracranial lesions in 14 cases: (1) intracranial hemorrhage was found in 7 cases, including intracerebral hematoma in 4 cases, micro-haemorrhage in 2 cases, and intracerebral hematoma accompanying by multiple intracerebral micro-haemorrhage foci in 1 case. All cases with intracerebral hematoma showed multiple lesions, which demonstrated high-density on CT images, and low or mixed signal on T1WI, high- oi intermediate signal with low-signal rim on T2WI and ring enhancement or no evident enhancement. Micro- haemorrhage manifested as multiple mini-mottling and strip hypointense foci on susceptibility weighted imaging, on which the detection rate of micro-haemorrhage foci was much higher than that on CT and other sequences of MRI. Among the 7 cases, one also had cerebral infarction and one subarachnoid hemorrhage. (2) Intracranial mass was found in 5 cases, among which two appeared as masses under or bestride cranium in the left frontal region with hypointensity on T1WI, mixed signal on T2WI, strong homogeneous enhancement and dual tail sign; one showed a mass in saddle area, with high density on CT, slightly low signal on T1WI, high signal on T2WI and heterogeneous enhancement, one case displayed a mass near lateral ventricle with iso-intensity on T1WI and T2WI and strong homogeneous enhancement; and one case manifested as cystic mass in the left fronto-apical lobe, with thick wall and ring enhancement. (3) Obstructive hydrocephalus was found in 1 case, manifesting dilation of ventricles above the aquaeductus mesencephali. (4) Meningopathy was found in 1 case, manifesting diffuse thickening of meninges with strong homogeneous enhancement on MRI. Pathological changes of spinal canal was found in 4 cases among which two showed para-spinal mass involving vertebral canal and causing bone destruction of adjacent ribs, one case showed fusiform mass posterior to vertebral canal with high and intermediate signal on T1WI and low and iso-signal on T2WI without enhancement; one showed zonale leison in thoracic cord with high signal on T2WI and fluid attenuated inversion recovery. Conclusion: The radiologic manifestations of adult CNSCL are various and the role of CT and MRI for the diagnosis of CNSCL may complement each other. SWI is suggested as routine examination for patients of leukemia, in whom intracerebral lesions were suspected in order to find micro-haemorrhage as early as possible and reduce the risk of intracerebral hematoma occurrence. (authors)

  10. A study of brain MRI findings and clinical response of bladder empting failure in brain bladder

    Energy Technology Data Exchange (ETDEWEB)

    Miyakoda, Keiichi (Yamashina Aiseikai Hospital, Kyoto (Japan)); Watanabe, Kousuke

    1993-02-01

    In 45 patients (38 males and 7 females; average age:78 years) with brain bladder, who did not have any peripheral neuropathies and spinal disturbance, cerebral findings of MRI (1.5 T) T[sub 2] enhanced image were analyzed in comparison with those of 7 control patients with normal urination after BPH operations. Patients with neurogenic bladder were divided into three groups as follows: 33 patients with a chief complaint of urinary disturbance (Group I), 9 patients with urinary incontinence (Group II) and 3 patients with balanced bladder (Group III). High frequency of lacune (24%) of the globus pallidus and low signalling of the corpus striatum (30%) was found in Group I patients, but low frequency in other Group patients and control patients. Furthermore, pathologic changes with various grades in the globus pallidus were observed in 91% of Group I patients. In the treatment of urinary disturbance, a high improvement rate of micturition disorder (77%) was obtained in patients treated with a combination of dantrolene and TURp (TUIbn for females). However, patients who had clear lacune of the globus pallidus showed the low improvement rate. It should be possible that the globus pallidus contributes to control the movement of the external sphincter and the pelvic base muscles as well as other striated muscles. Moreover, lacune was rarely found in the urination center of the brain-stem on MRI. (author).

  11. Unusual MRI findings in an immunocompetent patient with EBV encephalitis: a case report

    International Nuclear Information System (INIS)

    It is well-known that Epstein-Barr virus (EBV) can affect the central nervous system (CNS). Herein the authors report unusual timely Magnetic Resonance Imaging (MRI) brain scan findings in an immunocompetent patient with EBV encephalitis. Diffusion weighted MRI sequence performed during the acute phase of the disease was normal, whereas the Fast Relaxation Fast Spin Echo T2 image showed diffuse signal intensity changes in white matter. The enhancement pattern suggested an inflammatory response restricted to the brain microcirculation. Acyclovir and corticosteroid therapy was administered. After three weeks, all signal intensities returned to normal and the patient showed clinical recovery. This report demonstrates that EBV in an immunocompetent adult can present with diffuse, reversible brain white matter involvement in the acute phase of mononucleosis. Moreover, our case suggests that a negative DWI sequence is associated with a favorable improvement in severe EBV CNS infection. More extensive studies are needed to assess what other instrumental data can help to distinguish viral lesions from other causes in the acute phase of disease

  12. Kager's fat pad inflammation associated with HIV infection and AIDS: MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Godoy-Santos, Alexandre Leme; Fernandes, Tulio Diniz; Camanho, Gilberto Luis [University of Sao Paulo, Department of Orthopedic Surgery, Sao Paulo, SP (Brazil); Bordalo-Rodrigues, Marcelo; Rosemberg, Laercio [University of Sao Paulo, Department of Radiology, Sao Paulo (Brazil); Lei Munhoz Lima, Ana Lucia [University of Sao Paulo, Department of Infectious Disease, Sao Paulo (Brazil); Maffulli, Nicola [Mile End Hospital, Centre for Sports and Exercise Medicine Barts and The London School of Medicine and Dentistry, London (United Kingdom)

    2014-09-15

    To describe magnetic resonance imaging (MRI) features of Kager's fat pad inflammation in HIV-positive patients with lipodystrophy due to protease inhibitor treatment and posterior ankle pain. A case-control, cross-sectional study; group 1 included 14 HIV-positive patients using protease inhibitors, presenting lipodystrophy syndrome and having posterior ankle pain; group 2 (CGHIV-) included 112 HIV-negative patients without lipodystrophy syndrome who were being evaluated for posterior ankle pain; group 3 (CGHIV + 1) included 23 HIV-positive patients not using a protease inhibitor, without lipodystrophy syndrome and with posterior ankle pain; group 4 (CGHIV + 2) comprised 18 HIV-positive patients who were being treated with a protease inhibitor and had lipodystrophy syndrome but did not have posterior ankle pain. Images were evaluated for the presence of edema by two radiologists who were blinded to clinical features. Fisher's exact test was used to evaluate differences among the groups. Interobserver variation was tested using Cohen's kappa (?) statistic. The presence of edema within Kager's fat pad was strongly associated with symptoms in HIV-positive patients who had lipodystrophy (p ? 0.0001). Concordance between observers was excellent (? > 0.9). MRI findings of Kager's fat pad inflammation related to HIV/AIDS is a source of symptoms in HIV patients with posterior ankle pain using protease inhibitors and having lipodystrophy syndrome. (orig.)

  13. The comparison of MRI and histological findings of the hepatocellular carcinoma

    International Nuclear Information System (INIS)

    Using 17 nodes of resected samples from 14 patients with hepatocellular carcinoma (HCC), signal intensity of the MRI and histopathological findings were compared in detail by obtaining the high resolution images. Tumor/phantom signal intensity ratio (T/P) and liver parenchyma/phantom signal intensity ratio (L/P) were used in the evaluation of the MRI signal intensity. In 24 components which had the uniform histological structure of 17 nodes, the relationship between T/P value and histological differentiation was examined. The T/P values on T2-weighted images of grade 2 HCC were significantly higher than those of grade 1 HCC. These T/P values were higher than L/P values of HCC including grade 2 and the high signals were found on the images. There was no significant difference on the T1-weighted image. In 17 components, the correlation of T/P values and pathomorphological measurements was examined. The N/C ratio was strongly related to the T/P value and the nuclear size of hepatocytes, but not to the cell density and the cell size. (H.O.)

  14. Kager's fat pad inflammation associated with HIV infection and AIDS: MRI findings

    International Nuclear Information System (INIS)

    To describe magnetic resonance imaging (MRI) features of Kager's fat pad inflammation in HIV-positive patients with lipodystrophy due to protease inhibitor treatment and posterior ankle pain. A case-control, cross-sectional study; group 1 included 14 HIV-positive patients using protease inhibitors, presenting lipodystrophy syndrome and having posterior ankle pain; group 2 (CGHIV-) included 112 HIV-negative patients without lipodystrophy syndrome who were being evaluated for posterior ankle pain; group 3 (CGHIV + 1) included 23 HIV-positive patients not using a protease inhibitor, without lipodystrophy syndrome and with posterior ankle pain; group 4 (CGHIV + 2) comprised 18 HIV-positive patients who were being treated with a protease inhibitor and had lipodystrophy syndrome but did not have posterior ankle pain. Images were evaluated for the presence of edema by two radiologists who were blinded to clinical features. Fisher's exact test was used to evaluate differences among the groups. Interobserver variation was tested using Cohen's kappa (?) statistic. The presence of edema within Kager's fat pad was strongly associated with symptoms in HIV-positive patients who had lipodystrophy (p ? 0.0001). Concordance between observers was excellent (? > 0.9). MRI findings of Kager's fat pad inflammation related to HIV/AIDS is a source of symptoms in HIV patients with posterior ankle pain using protease inhibitors and having lipodystrophy syndrome. (orig.)

  15. Cystic changes in desmoplastic fibroma of bone: A new MRI finding

    International Nuclear Information System (INIS)

    Aim: To evaluate the magnetic resonance imaging features of desmoplastic fibroma (DF) of bone. Materials and methods: Two radiologists retrospectively evaluated imaging findings of pathologically confirmed DFs in eight patients. Involved sites and longitudinal location in long bones were evaluated using radiography and computed tomography (CT). At MRI, the presence of low signal areas on T2-weighted images (low-T2), enhancement, cystic changes, and locations of the mass were evaluated. The location of masses was evaluated, based on cortical disruption and adjacent soft-tissue extension. Results: Involved sites were the femur in three patients, the tibia in two, and the humerus, fibula, and pubic bone in one each. Of the seven masses in the long bones, three were located in the epi- and metaphysis, two in the meta- and diaphysis, one in the diaphysis, and one in the epiphysis. Seven masses had areas of low T2-weighted or heterogeneous enhancement, and three (38%) showed cystic changes. cortical disruption was seen at MRI in six of eight patients (88%). Conclusion: DFs contained cystic change. Cortical disruption may also occur, which may cause confusion with malignant lesions.

  16. Unusual MRI findings in an immunocompetent patient with EBV encephalitis: a case report

    Directory of Open Access Journals (Sweden)

    Mazzola Giovanni

    2011-03-01

    Full Text Available Abstract Blackground It is well-known that Epstein-Barr virus (EBV can affect the central nervous system (CNS. Case presentation Herein the authors report unusual timely Magnetic Resonance Imaging (MRI brain scan findings in an immunocompetent patient with EBV encephalitis. Diffusion weighted MRI sequence performed during the acute phase of the disease was normal, whereas the Fast Relaxation Fast Spin Echo T2 image showed diffuse signal intensity changes in white matter. The enhancement pattern suggested an inflammatory response restricted to the brain microcirculation. Acyclovir and corticosteroid therapy was administered. After three weeks, all signal intensities returned to normal and the patient showed clinical recovery. Conclusion This report demonstrates that EBV in an immunocompetent adult can present with diffuse, reversible brain white matter involvement in the acute phase of mononucleosis. Moreover, our case suggests that a negative DWI sequence is associated with a favorable improvement in severe EBV CNS infection. More extensive studies are needed to assess what other instrumental data can help to distinguish viral lesions from other causes in the acute phase of disease.

  17. MRI and X-ray findings of osteonecrosis in the knee

    International Nuclear Information System (INIS)

    This paper describes the retrospective comparison of MRI and X-ray findings of steroid-induced and idiopathic osteonecrosis in the knee to see their similarity and difference for the ultimate purpose of making the early diagnosis and treatment as well as knowing their pathogenesis. Subjects are images of 250 steroid-induced osteonecrotic knees of 136 patients (M 23/F 113, av. age of 39 y) among whom 114 patients (84%) having the bilateral disease, and of 50 knees of 48 patients (10/38, 71 y) with the idiopathic disease. The former group has the treatment history with a large dose (>30 mg/day) of predonisolone. X-ray images are classified as previously reported. T1-weighted spin echo (SE) and short inversion time inversion recovery (STIR) MRI is done with 1.5 T superconducting machine Gyroscan and images giving the necrotic finding are classified in the band (bright), mixed (dark in the bright) and diffuse (dark) types according to the contrast distribution in the lesion. The site of steroidal lesion is found to occur more frequently in the order of posterior lateral condyle, distal metaphysis and posterior medial condyle of femur, and necrosis, at the end of blood stream in the marrow, giving the band and mixed types. Idiopathic one occurs limitedly at the center of medial condyle of femur, giving the diffuse type. Idiopathic osteonecrosis thus differs from steroidal disease and its imaging findings do not lead to the conclusion that fracture is the cause of the idiopathy. (R.T)

  18. Systematic evaluation of MRI findings in different stages of treatment of cervical cancer: Potential of MRI on delineation of target, pathoanatomic structures, and organs at risk

    International Nuclear Information System (INIS)

    Purpose: To compare magnetic resonance imaging (MRI) findings at different stages of cervix cancer treatment and to define the potential of MRI to delineate the gross tumor volume (GTV), clinical target volume (CTV), pathoanatomic structures, and organs at risk (OAR) in brachytherapy. Methods and Materials: Forty-nine patients underwent MRI at diagnosis and at brachytherapy. The ability to discriminate anatomic structures on MRI was assessed (quality factor: 0 = inability to discriminate; 1 = fair discrimination; 2 = good discrimination; 3 = excellent discrimination). The overall ability to visualize (percentage of patients with quality factors greater than 0) and the overall discrimination quality score (mean quality factors of all patients) were estimated for the applicator, GTV at diagnosis (GTVD), GTV at brachytherapy (GTVBT)/'gray zones,' cervix rim/uterine corpus, OAR, vaginal wall, and parametria. Results: The overall ability to visualize the applicator on MRI at brachytherapy was 100%; for the GTVBT/'gray zones,' cervix rim/uterine corpus, OAR, and vaginal wall, visualization was 98% (overall discrimination quality factors: 1.2, 2.9, 2.1, 1.9, 1.7, and 2.6). Three of 4 borders of parametrial space were defined in more than 98% (discrimination quality factors: 2.9, 2.1, and 1.2). Conclusion: Magnetic resonance imaging provides appropriate information for definition of the applicator, GTV, CTV, pathoanatomic structures, and OAR that enables precise delineation for cervix cancer brachytherapy

  19. Cine-Club

    CERN Multimedia

    Cine-Club

    2011-01-01

    Lundi 12 décembre 2011 à 18:30 Salle du Conseil Comme chaque année avant Noël, le CINE-CLUB du CERN est heureux d’inviter petits et grands à une projection gratuite du film : Ponyo sur la falaise (Japon, 2008, Hayao Miyazaki) Le petit Sosuke vit avec sa mère sur une haute falaise surplombant la mer. Un beau jour, il découvre sur la plage caillouteuse Ponyo, une petite fille poisson. Ponyo est si fascinée par Sosuke et le monde terrestre que son désir le plus cher est de devenir un être humain. Mais Fujimoto, son magicien de père, n’est pas du tout d’accord avec cette idée et il la force à regagner les profondeurs de l’océan. Bien décidée à revoir Sosuke, Ponyo s’échappe de sa prison sous-marine, mais ce faisant elle déclenche une immense catastroph...

  20. Cine-Club

    CERN Multimedia

    Cine-Club

    2011-01-01

    Thursday 10 November 2011 at 20:30 CERN Council Chamber The Counterfeiters / Die Fälscher By: Stefan Ruzowitzky (Germany/Austria, 2007) 98 min With: Karl Markovics, August Diel, Devid Striesow The Counterfeiters is the true story of the largest counterfeiting operation in history, set up by the Nazis in 1936. Master counterfeiter Salomon ‘Sally’ Sorowitsch, a Jew without morals, is arrested and sent to Mauthausen concentration camp, where he weasels through by offering his ‘artistic’ services. After transfer to Sachsenhausen he’s given an official alternative: taking ‘artistic’ charge of a cons teams assigned to produce perfect forgeries of allied banknotes for the Third Reich. Survivor Sally accepts, but conscience matters among the team prove no less dangerous then a sadistic jailer, which only the CO may keep in check. Original version German; English subtitles Entrance: 2 CHF Projection from DVD http://cine...

  1. MRI findings of olivopontocerebellar atrophy and Machado-Joseph disease; Diagnostic value of transverse pontine fibers

    Energy Technology Data Exchange (ETDEWEB)

    Idezuka, Jiro; Onodera, Osamu; Tsuji, Shoji (Niigata Univ. (Japan). School of Medicine); Yuasa, Tatsuhiko; Ito, Jusuke

    1993-03-01

    Olivopontocerebellar atrophy (OPCA) and Machado-Joseph disease (MJD) occasionally show similar clinical signs and symptoms, which makes differential diagnosis of OPCA and MJD difficult. In 1990, Savoiardo et al. reported that the transverse pontine fibers of OPCA patients had high signal intensity on T[sub 2]-weighted MR images. To determine if the high signal intensity of the transverse pontine fibers is useful for the differential diagnosis of OPCA and MJD, we examined this abnormal intensity in patients diagnosed as OPCA or MJD. We observed the high intensity of transverse pontine fibers in all of the 18 OPCA patients. This finding, however, was not observed in any of the patients with the MJD. The high signal intensity of the transverse pontine fibers in T[sub 2]-weighted images is characteristic of OPCA patients. Furthermore, the atrophy of pontine tegmentum is characteristic of patients with MJD. These findings correlate well with pathological findings of OPCA and MJD, indicating the usefulness of these MRI findings for the differential diagnosis of OPCA and MJD. (author).

  2. MRI findings in multifetal pregnancies complicated by twin reversed arterial perfusion sequence (TRAP)

    International Nuclear Information System (INIS)

    Twin reversed arterial perfusion sequence (TRAP) is a rare complication in multifetal monochorionic pregnancies in which a normal ''pump'' twin provides circulation to an abnormal acardiac co-twin, resulting in high-output cardiac dysfunction in the pump twin. To define fetal MRI findings of TRAP sequence. Fetal MR images were retrospectively reviewed in 35 pregnancies complicated by TRAP sequence. Abnormalities of the pump twin, acardiac twin, umbilical cord, placenta and amniotic fluid were reviewed. Acardiac twins were classified as: acephalus (51%), anceps (40%), amorphus (9%), acormus (0%). Common findings in acardiac twins include subcutaneous edema (77%), absent cardiac structures (86%), absent or abnormal thoracic cavity (100%), abnormal abdominal organs (100%), superior limbs absent (46%) or abnormal (51%), and inferior limbs present but abnormal (83%). There were pump twin findings of cardiac dysfunction in 43% and intracranial ischemic changes in 3%. Umbilical cord anomalies were present in 97%. Acardiac twins present with a predictable pattern of malformation with poorly developed superior structures, more normally formed inferior structures and absent or rudimentary heart. Although usually absent, abnormal heart structures can be seen and do not exclude TRAP sequence. Pump twins are commonly normal with exception of findings of cardiac dysfunction and possible brain ischemia. (orig.)

  3. Churg-Strauss Syndrome with Cardiac Involvement: A Case Report with CT and MRI Findings

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Seong Joo; Cho, Young Jun; Kim, Keum; Hwang, Cheol Mok; Kim, Dae Ho [Dept. of Radiology, Konyang University College of Medicine, Daegu (Korea, Republic of); Choi, Eu Gene [Dept. of Internal Medicine, Konyang University College of Medicine, Daegu (Korea, Republic of)

    2012-02-15

    This is a case report of Churg-Strauss Syndrome (CSS) associated with cardiac involvement which is demonstrated in chest CT and cardiac MRI (CMR) without specific cardiac symptoms. A 32-year-old woman had a 3-year history of bronchial asthma, chronic sinusitis, and otitis media. The patient had various typical findings of CSS. The patient had no specific cardiac symptoms or signs such as chest pain, palpitations, syncope, or murmur, but she had diffuse low attenuation lesions in the inner wall of the left ventricle (LV) in contrast-enhanced CT. This corresponded to the area of subendocardial hyperenhancement in delayed contrast-enhanced CMR images. She was treated with steroids for 2 months. Follow-up delayed contrast-enhanced CMR of the LV showed a decrease in the size of the subendocardial enhancement area, and she had no symptoms. Therefore, the radiologist and clinician both should pay careful attention to observe possible cardiac involvement in case of CSS.

  4. Churg-Strauss Syndrome with Cardiac Involvement: A Case Report with CT and MRI Findings

    International Nuclear Information System (INIS)

    This is a case report of Churg-Strauss Syndrome (CSS) associated with cardiac involvement which is demonstrated in chest CT and cardiac MRI (CMR) without specific cardiac symptoms. A 32-year-old woman had a 3-year history of bronchial asthma, chronic sinusitis, and otitis media. The patient had various typical findings of CSS. The patient had no specific cardiac symptoms or signs such as chest pain, palpitations, syncope, or murmur, but she had diffuse low attenuation lesions in the inner wall of the left ventricle (LV) in contrast-enhanced CT. This corresponded to the area of subendocardial hyperenhancement in delayed contrast-enhanced CMR images. She was treated with steroids for 2 months. Follow-up delayed contrast-enhanced CMR of the LV showed a decrease in the size of the subendocardial enhancement area, and she had no symptoms. Therefore, the radiologist and clinician both should pay careful attention to observe possible cardiac involvement in case of CSS.

  5. Surgical results and MRI findings of cervical myelopathy treated with anterior decompression and fusion

    International Nuclear Information System (INIS)

    We reviewed 19 patients with cervical myelopathy treated with anterior decompression and fusion. Etiology of cervical myelopathy was cervical disc herniation (CDH) in 13 patients and cervical spondylosis (CSM) in 6. Clinical recovery rate (%) was calculated from preoperative cervical myelopathy score (JOA) and the score at follow-up. Correlation between the clinical recovery rate and MRI findings (area and flatness at the narrowest part of the spinal cord), age at surgery, duration of myelopathy and pre-operative clinical score were analyzed separately in the CDH and CSM groups. Clinical recovery rate averaged 69% in the CDH group and 75% in the CSM group. In the CDH group, average clinical recovery rate in patients younger than 60 years was 80 and in patients over 60 years was 60. There was a significant negative correlation between the clinical recovery rate and age at surgery (p<0.05). No significant correlation was found between the clinical recovery rate and other factors investigated. (author)

  6. Surgical results and MRI findings of cervical myelopathy treated with anterior decompression and fusion

    Energy Technology Data Exchange (ETDEWEB)

    Miyazato, Takenari; Teruya, Yoshimitsu [Chubu Tokushukai Hospital, Okinawa (Japan); Kinjo, Yukio [and others

    1995-09-01

    We reviewed 19 patients with cervical myelopathy treated with anterior decompression and fusion. Etiology of cervical myelopathy was cervical disc herniation (CDH) in 13 patients and cervical spondylosis (CSM) in 6. Clinical recovery rate (%) was calculated from preoperative cervical myelopathy score (JOA) and the score at follow-up. Correlation between the clinical recovery rate and MRI findings (area and flatness at the narrowest part of the spinal cord), age at surgery, duration of myelopathy and pre-operative clinical score were analyzed separately in the CDH and CSM groups. Clinical recovery rate averaged 69% in the CDH group and 75% in the CSM group. In the CDH group, average clinical recovery rate in patients younger than 60 years was 80 and in patients over 60 years was 60. There was a significant negative correlation between the clinical recovery rate and age at surgery (p<0.05). No significant correlation was found between the clinical recovery rate and other factors investigated. (author).

  7. Whole-body MRI in neurofibromatosis: incidental findings and prevalence of scoliosis

    International Nuclear Information System (INIS)

    To demonstrate incidental findings and scoliosis on whole-body MRI (WBMRI) in patients with neurofibromatosis type 1 and 2 (NF1 and NF2, respectively), and schwannomatosis. Institutional review board approval and written informed consent were obtained for this prospective HIPAA-compliant study. A total of 247 subjects (141 with NF1, 55 with NF2, 51 with schwannomatosis; 132 women (53.5%); mean age, 41 years, range, 18-97 years) underwent WBMRI using coronal STIR (TR/TE: 4190/111 ms, TI: 150 ms) and T1-weighted images (TR/TE: 454/10 ms), 10-mm slice thickness, imaging time ?40 min. Images were reviewed for the presence of incidental findings, outside of nerve sheath tumors. The presence of scoliosis was recorded and curve morphology was assessed and quantified. Incidental findings other than scoliosis were recorded in 104/247 (42%) patients, most often affecting the musculoskeletal system (65/247 patients, 26%). We found 16/247 (6.5%) significant incidental findings likely to affect clinical management, including avascular necrosis of bone in eight patients (five with NF2), eight insufficiency fractures, and four non-neurogenic neoplasms (Hodgkin's lymphoma, liposarcoma, dermoid cyst, large uterine myoma requiring excision). Scoliosis was seen in 50/247 patients (20%), including 8/55 with NF2 (15%) and 11/51 with schwannomatosis (22%). Incidental findings in the neurofibromatoses frequently involve the skeleton. Given the relatively high incidence of unsuspected osteonecrosis and stress fractures, close attention to the skeleton on WBMRI is advised. In addition, knowledge of common incidental findings can help clinicians prepare patients who undergo WBMRI for potential unexpected findings. (orig.)

  8. Whole-body MRI in neurofibromatosis: incidental findings and prevalence of scoliosis

    Energy Technology Data Exchange (ETDEWEB)

    Jaremko, Jacob L.; MacMahon, Peter J.; Torriani, Martin; Bredella, Miriam A. [Massachusetts General Hospital and Harvard Medical School, Musculoskeletal Imaging and Intervention, Department of Radiology, Boston, MA (United States); Merker, Vanessa L.; Plotkin, Scott R. [Massachusetts General Hospital, Department of Neurology and Cancer Center, Boston, MA (United States); Mautner, Victor F. [University Medical Center Hamburg-Eppendorf, Department of Neurology, Hamburg (Germany)

    2012-08-15

    To demonstrate incidental findings and scoliosis on whole-body MRI (WBMRI) in patients with neurofibromatosis type 1 and 2 (NF1 and NF2, respectively), and schwannomatosis. Institutional review board approval and written informed consent were obtained for this prospective HIPAA-compliant study. A total of 247 subjects (141 with NF1, 55 with NF2, 51 with schwannomatosis; 132 women (53.5%); mean age, 41 years, range, 18-97 years) underwent WBMRI using coronal STIR (TR/TE: 4190/111 ms, TI: 150 ms) and T1-weighted images (TR/TE: 454/10 ms), 10-mm slice thickness, imaging time {proportional_to}40 min. Images were reviewed for the presence of incidental findings, outside of nerve sheath tumors. The presence of scoliosis was recorded and curve morphology was assessed and quantified. Incidental findings other than scoliosis were recorded in 104/247 (42%) patients, most often affecting the musculoskeletal system (65/247 patients, 26%). We found 16/247 (6.5%) significant incidental findings likely to affect clinical management, including avascular necrosis of bone in eight patients (five with NF2), eight insufficiency fractures, and four non-neurogenic neoplasms (Hodgkin's lymphoma, liposarcoma, dermoid cyst, large uterine myoma requiring excision). Scoliosis was seen in 50/247 patients (20%), including 8/55 with NF2 (15%) and 11/51 with schwannomatosis (22%). Incidental findings in the neurofibromatoses frequently involve the skeleton. Given the relatively high incidence of unsuspected osteonecrosis and stress fractures, close attention to the skeleton on WBMRI is advised. In addition, knowledge of common incidental findings can help clinicians prepare patients who undergo WBMRI for potential unexpected findings. (orig.)

  9. MRI findings of the residual subluxation after reduction of developmental dysplasia of the hip

    International Nuclear Information System (INIS)

    After reduction of developmental dysplasia of the hip (DDH), not a few patients suffer from residual subluxation as well as acetabular dysplasia. Corrective surgery for these residual subluxations is sometimes performed before school-child age. It is occasionally difficult to determine whether the patient is candidate for the corrective surgery in the case with minor morphologic aberration. Therefore, we studied various MRI findings in residual subluxation, and examined if these MRI findings have an effect on natural courses such as growth or concentricity of the hip joint after reduction for DDH. The usefulness of MRI for determining the indication for the corrective surgery was also investigated. We studied 235 patients who underwent primary treatment for DDH during the past decade (between October, 1988 and September, 1998). Of the 235 patients, we studied 23 patients (23 cases; all unilateral cases) who showed residual subluxation and whose MR images were taken when they were around 3 years old, and during a follow-up period was available. Corrective surgery is performed in 11 patients, whereas the remaining 12 patients were conservatively observed the course of the residual subluxation. We investigated the existence of high signal intensity area (hereinafter referred to as HSIA) within the weight-bearing acetabular cartilage on T2-weighted MR coronal section images. Furthermore, conservatively observed patients were divided into two groups according to T2-weighted MR images. Based on simple X-ray images with time in both groups, the acetabular angle and the CE angle were measured. As results, many patients with residual subluxation showed localized HSIA in the weight-bearing acetabular cartilage on T2-weighted MR images. Although all patients who underwent corrective surgery showed HSIA, HSIA disappeared or decreased after the surgery. Of patients who were conservatively observed the course of the residual subluxation, patients showed HSIA on MR image had poor acetabular growth whereas patients showed no HSIA had favorable acetabular growth. The changes of HSIA in the weight-bearing acetabular cartilage on T2-weighted MR images could predict the poor or favorable course of acetabular growth, which is considered to be useful in determining the indication for the corrective surgery. (author)

  10. MRI findings in the lumbar spines of asymptomatic elite junior tennis players

    Energy Technology Data Exchange (ETDEWEB)

    Rajeswaran, G.; Healy, J.C. [Chelsea and Westminster Hospital NHS Foundation Trust, Department of Radiology, London, England (United Kingdom); Turner, M. [The National Tennis Centre, Lawn Tennis Association, London (United Kingdom); Gissane, C. [St Mary' s University, Twickenham, Middlesex (United Kingdom)

    2014-07-15

    To evaluate the MRI findings in the lumbar spines of asymptomatic elite junior tennis players. The lumbar spine MRI studies of 98 asymptomatic junior elite tennis players (51 male, 47 female) with a mean age of 18 years (age range 11.2-26.3 years; standard deviation 3.1) was reviewed by two consultant musculoskeletal radiologists using consensus opinion. Images were assessed using accepted classification systems. Four players (4 %) had no abnormality. Facet joint arthropathy occurred in 89.7 % of the players, being mild in 84.5 % of cases. There were 41 synovial cysts in 22.4 % of the cohort all occurring in the presence of facet arthropathy. Disc degeneration was noted in 62.2 % of players, being mild in 76.2 % of those affected. Disc herniation was noted in 30.6 % of players, with 86.1 % of these being broad based and 13.9 % being focal. There was nerve root compression in 2 %. There were 41 pars interarticularis abnormalities in 29.6 % of patients, 63.4 % of these being grades 1-3. There was grade 1 spondylolisthesis in 5.1 % of players. The prevalence of facet joint arthropathy, disc degeneration, disc herniation and pars interarticularis fracture was lower in female players than in male and lower in the under 16-year-olds compared with the over 20-year-olds. There is a significant amount of underlying pathology that would normally go undetected in this group of asymptomatic elite athletes. Whilst these findings cannot be detected clinically, their relevance is in facilitating appropriate prehabilitation to prevent loss of playing time and potentially career-ending injuries. (orig.)

  11. Dynamic contrast-enhanced MRI of anterior prostate cancer: morphometric assessment and correlation with radical prostatectomy findings

    International Nuclear Information System (INIS)

    The purpose of the study was to relate morphometric features of prostate cancers in the anterior compartment of the prostate by dynamic contrast-enhanced (DCE) MRI to subsequent histopathologic findings. We prospectively performed DCE-MRI before biopsy in patients with suspected prostate cancer and selected those showing both a suspicious lesion at MRI and positive biopsies in the anterior compartment of the gland. Tumor contours, margins, largest surface areas and volumes were assessed at MRI and histopathology, when available. Anterior compartment tumors were classified according to transition zone (TZ) boundaries with the peripheral zone (PZ) or with the anterior fibromuscular stroma (SFMA). Forty-three patients were included in this study [median PSA 12.7 ng/ml (3.6-72)]. Whole-mount radical prostatectomy specimens were available in 27 cases. Of the anterior cancers, 89% had ill-defined margins at T2-weighted MRI. Cancer location and contour established at MRI agreed well with histopathology in the 27 cases. Median largest surface area and volume were 1.38 cm2 (0.35-5.82) and 1.01 cc (0.15-7.4) for MRI versus 1.86 cm2 (0.2-14) and 2.84 cc (0.33-28.92) for histopathology with respective correlation coefficients (r2) of 0.73 and 0.69. The site of origin could be accurately determined for the 15 tumors of less than 3 cc. We found a good relationship between DCE-MRI and histopathology for localization, morphologic description and volume assessment of anterior prostate cancers. (orig.)

  12. Dynamic contrast-enhanced MRI of anterior prostate cancer: morphometric assessment and correlation with radical prostatectomy findings

    Energy Technology Data Exchange (ETDEWEB)

    Lemaitre, Laurent [Centre Hospitalier Regional Universitaire de Lille, Department of Radiology, Lille Cedex (France)]|[Centre Hospitalier Regional Universitaire de Lille, Department of genitourinary radiology, Lille Cedex (France); Puech, Philippe; Poncelet, Edouard [Centre Hospitalier Regional Universitaire de Lille, Department of Radiology, Lille Cedex (France); Bouye, Sebastien; Biserte, Jacques; Villers, Arnauld [Centre Hospitalier Regional Universitaire de Lille, Department of Urology, Lille Cedex (France); Leroy, Xavier [Centre Hospitalier Regional Universitaire de Lille, Department of Pathology, Lille Cedex (France)

    2009-02-15

    The purpose of the study was to relate morphometric features of prostate cancers in the anterior compartment of the prostate by dynamic contrast-enhanced (DCE) MRI to subsequent histopathologic findings. We prospectively performed DCE-MRI before biopsy in patients with suspected prostate cancer and selected those showing both a suspicious lesion at MRI and positive biopsies in the anterior compartment of the gland. Tumor contours, margins, largest surface areas and volumes were assessed at MRI and histopathology, when available. Anterior compartment tumors were classified according to transition zone (TZ) boundaries with the peripheral zone (PZ) or with the anterior fibromuscular stroma (SFMA). Forty-three patients were included in this study [median PSA 12.7 ng/ml (3.6-72)]. Whole-mount radical prostatectomy specimens were available in 27 cases. Of the anterior cancers, 89% had ill-defined margins at T2-weighted MRI. Cancer location and contour established at MRI agreed well with histopathology in the 27 cases. Median largest surface area and volume were 1.38 cm{sup 2} (0.35-5.82) and 1.01 cc (0.15-7.4) for MRI versus 1.86 cm{sup 2} (0.2-14) and 2.84 cc (0.33-28.92) for histopathology with respective correlation coefficients (r{sup 2}) of 0.73 and 0.69. The site of origin could be accurately determined for the 15 tumors of less than 3 cc. We found a good relationship between DCE-MRI and histopathology for localization, morphologic description and volume assessment of anterior prostate cancers. (orig.)

  13. MRI findings in Kirner deformity: normal insertion of the flexor digitorum profundus tendon without soft-tissue enhancement

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jaejoon; Ahn, Joong Kyong; Koh, Eun-Mi; Cha, Hoon-Suk [Sungkyunkwan University School of Medicine, Department of Medicine, Samsung Medical Center, Seoul (Korea); Choi, Sang-Hee [Sungkyunkwan University School of Medicine, Department of Radiology, Samsung Medical Center, Seoul (Korea)

    2010-09-15

    Kirner deformity is characterized by volar and radial incurvature of the distal phalanx of the 5th finger. A proposed causative mechanism includes abnormal distal insertion of the flexor digitorum profundus tendon along the volar surface of the distal phalanx of the 5th finger. A chronic inflammatory process or altered vascularisation of the soft tissues has also been suggested as the underlying causative mechanism based on MRI findings. We present a teenage boy with Kirner deformity, along with supplementary imaging of his father who also has the deformity, to illustrate MRI findings that dispute the above hypotheses. MRI in both son and father show normal insertion of the deep flexor tendon and no signs of inflammation. (orig.)

  14. MRI findings in Kirner deformity: normal insertion of the flexor digitorum profundus tendon without soft-tissue enhancement

    International Nuclear Information System (INIS)

    Kirner deformity is characterized by volar and radial incurvature of the distal phalanx of the 5th finger. A proposed causative mechanism includes abnormal distal insertion of the flexor digitorum profundus tendon along the volar surface of the distal phalanx of the 5th finger. A chronic inflammatory process or altered vascularisation of the soft tissues has also been suggested as the underlying causative mechanism based on MRI findings. We present a teenage boy with Kirner deformity, along with supplementary imaging of his father who also has the deformity, to illustrate MRI findings that dispute the above hypotheses. MRI in both son and father show normal insertion of the deep flexor tendon and no signs of inflammation. (orig.)

  15. Postoperative MRI findings after anterior cruciate ligament reconstruction. A prospective study with 50 patients

    International Nuclear Information System (INIS)

    Aim: Identification of typical postoperative change after anterior cruciate ligament reconstruction (sutures, tendon grafts) and comparison with clinical tests and ultrasound. Patients and methods: 50 patients with anterior cruciate ligament ruptures were examinated with MRI (1.0 T, surface coil, sagittal T1-3DFT-Fast and sagittal spin-echo), US and clinical function tests (Lachmann, pivot-shift, anterior drawer test). Results: In 19 of 21 patients with continuous low-intensity ligament structures in the MRI, knee stability was very good or good in the clinical tests and US. In 17 of 20 patients with a diagnosis of partial rupture at MRI, we also found a stable knee. 5 of 7 patients with the MRI-signs of ligament rupture showed knee stability at US and clinical tests. Furthermore, at MRI we found minor effusions in 10 patients, meniscus tears in 8 patients and ligament impingement in 2 patients. Conclusion: MRI is a valuable method for evaluating and assessing anterior ligament reconstructions. We found a good correlation between the continuous low-intensity ligaments at MRI and knee-stability. In contrast there is a bad correlation between discontinuous ligament structures at MRI and clinical stability of the knee. MRI seems to provide more information than US and clinical tests (for example: minor effusion, meniscus tears, ligament impingement, bone lesions). (orig.)

  16. MRI findings in renal transplant recipients with hip and knee pain

    International Nuclear Information System (INIS)

    Purpose: To evaluate and demonstrate the MRI findings of renal transplant recipients with hip and knee pain and to investigate the most common etiology of pain. Materials and methods: 69 hip MRIs of 57 patients with hip pain and 30 knee MRIs of 24 patients with knee pain with no history of trauma were retrospectively evaluated by two radiologists. Results: In the evaluation of hip MRIs, 24 patients had avascular necrosis and effusion, 2 patients had bone marrow edema consistent with early stage of avascular necrosis. 18 patients had only intraarticular effusion, 6 patients had tendinitis, 6 patients had bursitis and 1 patient had soft tissue abscess. Five patients had muscle edema and five patients had muscle atrophy as additional findings to the primary pathologies. Among patients with knee pain, nine patients had degenerative joint disease. Seven patients had chondromalacia, five had bone marrow edema, six had meniscal tear, six had ligament rupture and two had bone infarct. Three of the patients had muscle edema accompanying to other pathologies. Conclusion: The most common etiology of hip pain in renal transplant recipients is avascular necrosis as expected, intraarticular effusion is found to be Second reason for pain. However, knee pain is explained by ligament pathology, meniscal tear, chondromalacia or degenerative joint disease rather than osteonecrosis.

  17. MRI findings in renal transplant recipients with hip and knee pain

    Energy Technology Data Exchange (ETDEWEB)

    Donmez, Fuldem Yildirim [Baskent University Faculty of Medicine, Department of Radiology, Fevzi Cakmak Caddesi 10. sokak no: 45, Bahcelievler 06490, Ankara (Turkey)], E-mail: fuldemyildirim@yahoo.com; Basaran, Ceyla [Baskent University Faculty of Medicine, Department of Radiology, Fevzi Cakmak Caddesi 10. sokak no: 45, Bahcelievler 06490, Ankara (Turkey)], E-mail: ceylab@baskent-ank.edu.tr; Ulu, Esra Meltem Kayahan [Baskent University Faculty of Medicine, Department of Radiology, Fevzi Cakmak Caddesi 10. sokak no: 45, Bahcelievler 06490, Ankara (Turkey)], E-mail: emkayahanulu@yahoo.com; Uyusur, Arzu [Baskent University Faculty of Medicine, Department of Radiology, Fevzi Cakmak Caddesi 10. sokak no: 45, Bahcelievler 06490, Ankara (Turkey)], E-mail: arzuuyusur@yahoo.com; Tarhan, Nefise Cagla [Baskent University Faculty of Medicine, Department of Radiology, Fevzi Cakmak Caddesi 10. sokak no: 45, Bahcelievler 06490, Ankara (Turkey)], E-mail: caglat@baskent-ank.edu.tr; Muhtesem Agildere, A. [Baskent University Faculty of Medicine, Department of Radiology, Fevzi Cakmak Caddesi 10. sokak no: 45, Bahcelievler 06490, Ankara (Turkey)], E-mail: amuhtesem@superonline.com

    2009-09-15

    Purpose: To evaluate and demonstrate the MRI findings of renal transplant recipients with hip and knee pain and to investigate the most common etiology of pain. Materials and methods: 69 hip MRIs of 57 patients with hip pain and 30 knee MRIs of 24 patients with knee pain with no history of trauma were retrospectively evaluated by two radiologists. Results: In the evaluation of hip MRIs, 24 patients had avascular necrosis and effusion, 2 patients had bone marrow edema consistent with early stage of avascular necrosis. 18 patients had only intraarticular effusion, 6 patients had tendinitis, 6 patients had bursitis and 1 patient had soft tissue abscess. Five patients had muscle edema and five patients had muscle atrophy as additional findings to the primary pathologies. Among patients with knee pain, nine patients had degenerative joint disease. Seven patients had chondromalacia, five had bone marrow edema, six had meniscal tear, six had ligament rupture and two had bone infarct. Three of the patients had muscle edema accompanying to other pathologies. Conclusion: The most common etiology of hip pain in renal transplant recipients is avascular necrosis as expected, intraarticular effusion is found to be Second reason for pain. However, knee pain is explained by ligament pathology, meniscal tear, chondromalacia or degenerative joint disease rather than osteonecrosis.

  18. MRI findings of acute cerebral swelling and brain edema in the acute stage

    International Nuclear Information System (INIS)

    We report two cases, one of acute cerebral swelling and the other with a major stroke, whose MRI has shown very interesting findings. Case 1, a 32-year-old male, was admitted to our service because of a lowering of his consciousness immediately after a head injury. On admission, the patient was semicomatous (E1M2V1, with anisocoria (R > L). His plain skull X-ray was normal. A CT scan, however, demonstrated right isodensity hemispheric swelling associated with a subarachnoid hemorrhage in the right Sylvian fissure. A right carotid angiogram showed no vascular disorders. MR imaging of the spin density demonstrated a hyperintensitive thickening of the gray matter in the whole right hemisphere. Case 2, a 58-year-old female, was admitted because of a sudden onset of loss of consciousness, with right hemiparesis and dysarthria. On admission, her consciousness was semicomatous (E1M3V1), and it deteriorated to a deep coma 1 hour later. A CT scan demonstrated a diffuse left hemispheric low density, with a finding of hemorrhagic infarction in the basal ganglia. MR imaging of the spin density showed a hyperintensitive thickening of the gray matter resembling that of Case 1. The findings of the spin-echo images of our two cases showed a hyperintensitive thickening of the gray matter in both. The hyperintensity and thickening of the gray matter apparently indicated a sort of hyperemia and brain edema. These findings led us to suspect that the hyperemia associated with acute cerebral swelling and ischemic brain edema of our two cases originated in the gray matter, although it has been considered that the pathogenesis of acute cerebral swelling is not known and that brain edema, especially vasogenic edema, will mostly develop in the white matter rather than in the gray matter. (author)

  19. CERN CINE CLUB

    CERN Multimedia

    CERN CINE CLUB

    2010-01-01

    CERN CINE CLUB Thursday 24 June 2010 at 20:30 / Jeudi 24 Juin 2010 à 20:30 CERN Main Auditorium / Amphithéâtre Principal   The Raggedy Rawney By/de : Bob Hoskins (UK, 1988) - 104 min With/avec: Dexter Fletcher, Bob Hoskins, David Hill, Zoe Nathanson, Zoe Wanamaker Bob Hoskins makes his directorial debut with this lyrical, mystical fable about the strength of family and the transcendence of love. When a young military recruit named Tom goes AWOL after his first taste of battle, he must disguise himself with face paint and women’s clothing to avoid being captured by his vengeful commanding officer. He is instead discovered and taken in by Darky, the leader of an eccentric group of traveling gypsies, who thinks he is a «rawney», a half-mad, half-magical woman who brings good fortune. But when Tom begins a love affair with Darky’s daughter, he sets off a chain reaction of events that will soon put all of their lives in grave ...

  20. Cognitive profile and structural findings in Wilson?s disease: A neuropsychological and MRI-based study

    Directory of Open Access Journals (Sweden)

    Hegde Shantala

    2010-12-01

    Full Text Available Background: Systematic studies on neuropsychological profile in patients with Wilson?s disease (WD are far and few. Aim: To examine the profile of cognitive deficits and their magnetic resonance imaging (MRI findings in patients with WD. Patients and Methods: Twelve confirmed patients of WD (age at onset and evaluation, 13.7±11.2 and 21.7±5.3 years, respectively; M-F ratio, 7:5 on de-coppering therapy constituted the study sample. Battery of neuropsychological tests measuring mental speed, motor speed, sustained attention, focused attention, verbal category fluency, verbal working memory, response inhibition, planning, concept formation, set-shifting ability, verbal and visual learning and memory were administered. Phenotypic details and observations on MRI of brain carried out within six months of neuropsychological assessment were documented. Results: Neuropsychological assessment elicited cognitive deficits in multiple domains in all but one patient, who had normal MRI. Percentage of patients in the deficit range in various domains included: motor speed: 73%; verbal working memory, sustained and focused attention: 50%; verbal learning: 42%; visuo-constructive ability, verbal memory, mental speed: 33%-34%; verbal fluency, set-shifting ability, visual memory, verbal memory: 25%-27%; and verbal recognition: 17%. MRI was normal in three patients, and revealed variable abnormalities in the remaining: cerebral atrophy in 3; brainstem atrophy in 2; signal changes in basal ganglia in 9; and brainstem signal changes in 5. None had subcortical white matter changes. Two patients with normal MRI showed cognitive deficits. Conclusion: This study provides insight into the complex cognitive and brain changes observed on MRI in WD. Use of advanced MRI techniques in a larger cohort may improve understanding regarding functional and structural brain changes observed in similar disorders.

  1. MRI findings of the antero-superior attachment of the disc in TMJ internal derangement

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Bong Hae; Jung, Yun Hoa [Pusan National Univ. School of Dentistry, Pusan (Korea, Republic of)

    2006-06-15

    To describe the MRI findings of the antero-superior attachment of the disc in patients with internal derangement. One hundred fifty-six MR images from 40 normal subjects and 55 abnormal subjects were classified into three study groups of normal, anterior disc displacement with reduction and anterior disc displacement without reduction. On both closed- and open-mouth proton density sagittal images, the depiction of the antero-superior attachment of the disc and its demarcation from the disc were evaluated in three cuts of lateral, central and medial one thirds of the condyle. The depiction of antero-superior attachment was more frequent by the order of normal, anterior disc displacement with reduction and anterior disc displacement without reduction groups, and the significant differences were found on lateral cut of the closed images and lateral and central cuts of the open images. In study for the demarcation between the antero-superior attachment and the disc the lateral cut of the closed images and all three cuts of the open images showed significant differences. Open images are useful to show the difference in depiction of the ant ero-superior attachment of the disc among the TMJ groups.

  2. Correlation between developmental disorders and MRI findings in very low birth weight infants

    International Nuclear Information System (INIS)

    We investigated the prevalence of developmental disorders in very low birth weight infants, their risk factors during the neonatal period, and the correlation between their neurological symptoms and their MRI findings. Seventy-three infants, who were followed up for more than 5 years in the developmental clinic, were enrolled. The developmental disorders included 6 patients with cerebral palsy (CP) and 6 patients with mental retardation (MR). The types of CP were as follows: spastic diplegia (3), spastic quadriplegia (2), athetotic quadriplegia (1). Intraventricular hemorrhage (IVH) and mechanical ventilation (MV) were significant risk factors for CP and MR and retinopathy was also a significant risk factor for MR. Periventricular areas of bright signal intensity on T2 (TR 2000 msec/TE 120 mse) weighted images, compatible with old, small white matter infarcts, gliosis or demyelination, were observed in only three of the seven patients. We measured the width of anterior horns, the maximum diameter of cerebrum, and the minimum thickness of white matter in occipital lobe on T1 (TR 500 msec/TE 20 msec) weighted transaxial images in eight patients (five patients with CP, three patients with MR). The maximum diameters of cerebrums and the minimum thickness of white matters were significantly smaller in patients with CP or MR than those in controls, respectively. The DQ of patients significantly correlated with the maximum diameters of cerebrums and the minimum thickness of white matters in left occipital lobe significantly correlated with DQ. (author)

  3. Three Tesla MRI for the diagnosis of meniscal and anterior cruciate ligament pathology: a comparison to arthroscopic findings

    International Nuclear Information System (INIS)

    Aim: To assess the accuracy of 3 T magnetic resonance imaging (MRI) in the evaluation of meniscal and anterior cruciate ligament (ACL) injury. Materials and methods: Sixty-one consecutive patients were identified who were referred for evaluation of suspected intra-articular pathology with a 3 T MRI and who, subsequently, underwent an arthroscopic procedure of the knee were included for the study. Two musculoskeletal radiologists interpreted the images. The sensitivity, specificity, positive predictive value, and negative predictive value were then calculated for the MRI versus the arthroscopic findings as a reference standard. Results: The sensitivity and specificity for the overall detection of meniscal tears in this study was 84 and 93%, respectively. The results for the medial meniscus separately were 91 and 93% and for the lateral 77 and 93%. The evaluation of ACL integrity was 100% sensitive and specific. The meniscal tear type was correctly identified in 75% of cases and its location in 94%. Conclusion: This study demonstrates good results of 3 T MRI in the evaluation of the injured knee. Caution should still be given to the interpretation on MRI of a lateral meniscus tear, and it is suggested that the standard diagnostic criteria of high signal reaching the articular surface on two consecutive image sections be adhered to even at these higher field strengths

  4. Three Tesla MRI for the diagnosis of meniscal and anterior cruciate ligament pathology: a comparison to arthroscopic findings

    Energy Technology Data Exchange (ETDEWEB)

    Sampson, M.J. [Department of Radiology Sports Surgery Clinic, Santry Demesne, Dublin (Ireland)], E-mail: allymattsampson@hotmail.com; Jackson, M.P.; Moran, C.J.; Moran, R. [Department of Orthopaedics, Sports Surgery Clinic, Santry Demesne, Dublin (Ireland); Eustace, S.J. [Department of Radiology Sports Surgery Clinic, Santry Demesne, Dublin (Ireland); Shine, S. [Department of Radiology, Cappagh Hospital, Finglas, Dublin (Ireland)

    2008-10-15

    Aim: To assess the accuracy of 3 T magnetic resonance imaging (MRI) in the evaluation of meniscal and anterior cruciate ligament (ACL) injury. Materials and methods: Sixty-one consecutive patients were identified who were referred for evaluation of suspected intra-articular pathology with a 3 T MRI and who, subsequently, underwent an arthroscopic procedure of the knee were included for the study. Two musculoskeletal radiologists interpreted the images. The sensitivity, specificity, positive predictive value, and negative predictive value were then calculated for the MRI versus the arthroscopic findings as a reference standard. Results: The sensitivity and specificity for the overall detection of meniscal tears in this study was 84 and 93%, respectively. The results for the medial meniscus separately were 91 and 93% and for the lateral 77 and 93%. The evaluation of ACL integrity was 100% sensitive and specific. The meniscal tear type was correctly identified in 75% of cases and its location in 94%. Conclusion: This study demonstrates good results of 3 T MRI in the evaluation of the injured knee. Caution should still be given to the interpretation on MRI of a lateral meniscus tear, and it is suggested that the standard diagnostic criteria of high signal reaching the articular surface on two consecutive image sections be adhered to even at these higher field strengths.

  5. Structural Findings in the Brain MRI of Patients with Acute Carbon Monoxide Poisoning

    Directory of Open Access Journals (Sweden)

    Yasmin Davoudi

    2014-09-01

    Conclusion: The white matter and globus pallidus were the most common affected regions in brain following acute CO poisoning. Signal abnormalities and restricted diffusion in MRI were correlated with duration of exposure to CO but not with the carboxyhemoglobin levels.

  6. The clinical and genetic correlates of MRI findings in myotonic dystrophy

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, G. [Neuromuscular and Genetic Research Group, Department of Radiology, Justus Liebig University, Giessen (Germany); Damian, M.S. [Department of Neurology, University of Giessen (Germany); Koch, M. [Department of Human Genetics, University of Marburg (Germany); Schilling, G. [Department of Psychiatry, University of Giessen (Germany); Fach, B. [Department of Neurology, University of Giessen (Germany); Stoeppler, S. [Department of Neurology, University of Giessen (Germany)

    1996-10-01

    Amplification of an unstable CTG trinucleotide repeat sequence in a protein kinase gene on chromosome 19 has recently been recognised as the molecular basis of myotonic dystrophy (DM), a multisystem disorder with a wide spectrum of muscular and extramuscular manifestations. The CTG expansion of 40 patients was assessed by direct genotype analysis of the white blood cell DNA and correlated with MRI of the brain and muscles, and with functional clinical data. Cerebral pathology on MRI consisted of diffuse atrophy (68 %), subcortical white matter lesions (65 %), wide Virchow-Robin spaces (38 %) and thickening of the skull (35 %). Cerebral atrophy and extent of white matter disease correlated significantly with mental retardation, duration of disease and CTG fragment amplification. MRI of the muscular system showed fatty degeneration of different degrees in neighbouring muscles causing a mosaic pattern of the thigh in 38 % and the calf in 44 %. Muscular changes on MRI were strongly correlated with muscular impairment but less strongly with CTG expansion. Changes on MRI reflect the stage of development of tissue pathology in DM, modified by defect of the DM gene. Pathology on MRI is strongly correlated with functional deficits. (orig.). With 8 figs., 3 tabs.

  7. The clinical and genetic correlates of MRI findings in myotonic dystrophy

    International Nuclear Information System (INIS)

    Amplification of an unstable CTG trinucleotide repeat sequence in a protein kinase gene on chromosome 19 has recently been recognised as the molecular basis of myotonic dystrophy (DM), a multisystem disorder with a wide spectrum of muscular and extramuscular manifestations. The CTG expansion of 40 patients was assessed by direct genotype analysis of the white blood cell DNA and correlated with MRI of the brain and muscles, and with functional clinical data. Cerebral pathology on MRI consisted of diffuse atrophy (68 %), subcortical white matter lesions (65 %), wide Virchow-Robin spaces (38 %) and thickening of the skull (35 %). Cerebral atrophy and extent of white matter disease correlated significantly with mental retardation, duration of disease and CTG fragment amplification. MRI of the muscular system showed fatty degeneration of different degrees in neighbouring muscles causing a mosaic pattern of the thigh in 38 % and the calf in 44 %. Muscular changes on MRI were strongly correlated with muscular impairment but less strongly with CTG expansion. Changes on MRI reflect the stage of development of tissue pathology in DM, modified by defect of the DM gene. Pathology on MRI is strongly correlated with functional deficits. (orig.). With 8 figs., 3 tabs

  8. CT and MRI findings of cirrhosis-related benign nodules with ischaemia or infarction after variceal bleeding

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Y.K., E-mail: jmyr@dreamwiz.co [Department of Diagnostic Radiology, Research Institute of Clinical Medicine, Chonbuk National University Hospital and Medical School, Jeon Ju (Korea, Republic of); Park, G.; Kim, C.S.; Han, Y.M. [Department of Diagnostic Radiology, Research Institute of Clinical Medicine, Chonbuk National University Hospital and Medical School, Jeon Ju (Korea, Republic of)

    2010-10-15

    Aim: To present computed tomography (CT) and magnetic resonance imaging (MRI) findings of cirrhosis-related benign nodules with ischaemia or infarction. Materials and methods: Sixteen consecutive patients (14 men and two women) who had been diagnosed with cirrhosis-related benign nodules with ischaemia or infarction after variceal bleeding based on the results of dynamic CT (n = 15) and MRI (n = 8) were included in this study. Five patients had histopathological confirmation via liver transplantation (n = 2) and percutaneous biopsy (n = 3). Images were analyzed for the enhancement pattern, signal intensities, location, and configuration of the lesions. Results: Most of the lesions were depicted as multifocal discrete or clustered nodules with some irregular patchy areas (size range 3-28 mm). They were predominantly found in subcapsular area or caudate lobe. Most nodular lesions were seen as hypoattenuating (hypointense) nodules with rim enhancement during dynamic CT or MRI. On T2-weighted images, nodular lesions were predominantly seen as target appearing hyperintense nodules. On follow-up images (range 2-24 months), most of the lesions disappeared or decreased in size. Conclusion: CT and MRI can be used to demonstrate characteristic findings of cirrhosis-related benign nodules with ischaemia or infarction. Rapid resolution of the nodules at follow-up imaging can also be helpful for diagnosing these lesions.

  9. Cine MRI for the evaluation of influences of regional left ventricular wall motion abnormalities on global cardiac function after myocardial infarction and revascularization therapy; CINE-MRT zur Untersuchung der Auswirkungen regionaler linksventrikulaerer Wandbewegungstoerungen auf die globale Herzfunktion nach Herzinfarkt und Revaskularisierung

    Energy Technology Data Exchange (ETDEWEB)

    Sandstede, J.; Lipke, C.; Beer, M.; Pabst, T.; Kenn, W.; Hahn, D. [Wuerzburg Univ. (Germany). Inst. fuer Roentgendiagnostik; Harre, K.; Neubauer, S. [Wuerzburg Univ. (Germany). Medizinische Klinik

    1999-12-01

    Purpose: To determine changes in global cardiac function and mass caused by infarct-associated regional wall motion abnormalities and to compare the changes after revascularization in patients with and without improvement of regional contractility. Materials and Methods: 21 patients with regional left ventricular wall motion abnormalities and associated coronary artery stenoses requiring revascularization were examined with a Cine FLASH-2D sequence 26{+-}12 days after their first myocardial infarction and re-examined three months after revascularization. Regional contractility and volumes and masses of both ventricles were determined. Results: After revascularization, regional wall motion improvement led to decreased left ventricular volumes and improved ejection fractions, whereas patients with persisting wall motion defects showed unchanged left ventricular functional parameters. Comparing both groups of patients, the patients with improvement of regional contractility revealed lower end-systolic volumes and higher ejection fractions at follow-up. Cardiac masses and right ventricular parameters were not different, patients with a depressed right ventricular ejection fraction showed improvement at follow-up. Discussion: After myocardial infarction, revascularization of the infarct-related coronary artery leads to an improvement of left ventricular function only if there is also an improvement of regional contractility. An effect on right ventricular function was not observed three months after the first small- or middle-sized myocardial infarction. (orig.) [German] Ziel: Beurteilung der Auswirkungen regionaler Infarkt-assoziierter linksventrikulaerer (LV) Wandbewegungsstoerungen auf die globale Herzfunktion und der Veraenderungen bei Patienten mit und ohne Kontraktilitaetszunahme nach Revaskularisierung. Methoden: 21 Patienten mit LV Wandbewegungsstoerungen im Versorgungsgebiet einer stenosierten Koronararterie mit Indikation zur Revaskularisierung wurden 26{+-}12 Tage nach erstmaligem Herzinfarkt sowie drei Monate nach Revaskularisierung mit der Cine-MRT untersucht. Bestimmt wurden die regionale Kontraktilitaet des infarzierten Areals sowie die Massen- und Funktionsparameter beider Herzventrikel. Ergebnisse: Nach Revaskularisierung kam es bei Zunahme der regionalen Kontraktilitaet zu einer Abnahme des LV Volumens sowie einer Zunahme der Ejektionsfraktion (EF), bei persistierenden Wandbewegungsstoerungen war die LV Funktion unveraendert. Patienten mit regionaler Erholung hatten ein niedrigeres LVESV und eine hoehere LVEF nur bei der Kontrolle. Herzmassen und RV Parameter waren vergleichbar, bei Patienten mit erniedrigter RVEF kam es zu einer Verbesserung im Verlauf. Schlussfolgerungen: Nach einem Herzinfarkt mit linksventrikulaeren Wandbewegungsstoerungen fuehrt eine Revaskularisierung der Infarktarterie nur dann zu einer Verbesserung der LV Funktion, wenn auch die regionale Kontraktilitaet zunimmt. Eine Funktionsbeeintraechtigung des rechten Ventrikels war nach drei Monaten bei Patienten mit geringer bis mittlerer Infarktgroesse nicht zu beobachten. (orig.)

  10. MRI bone marrow findings in 63 patients with type I Gaucher's disease

    International Nuclear Information System (INIS)

    Purpose: To determine whether MR bone marrow findings in Gaucher patients may help to identify patients at high risk of developing severe Gaucher bone complications exemplified by avascular necrosis (AVN) of the femoral head. Materials and Methods: MR images were obtained in 63 Type I Gaucher patients through a standard protocol using coronal T1 and T2-weighted sequences of the lower extremities. The location and extent of infiltrated marrow was established using a semi-quantitative MRI scoring method (Duesseldorf Gaucher score, DGS) and the morphological pattern of bone marrow involvement determined (whether homogeneous type A or non-homogeneous type B). The active marrow process with bone edema and AVN of the femoral head were also analyzed. Results: Bone marrow involvement was observed in femoral sites more than in tibial sites. A high DGS was significantly correlated with type B morphology and femoral AVN (both p < 0.0001). Splenectomized patients showed a significantly higher Duesseldorf Gaucher score and type B morphology than non-splenectomized patients (both p < 0.05). AVN was seen in 46 % of patients with type B morphology versus 3 % in type A morphology (p < 0.0001). DGS and morphology of bone marrow involvement were not significantly correlated with active marrow processes. Conclusion: Type B marrow morphology and extensive marrow packing were significantly associated with AVN of the femoral head (both p < 0.0001). These patterns are considered predictive and may be employed in a disease management context to alert physicians to the need for urgent therapeutic measures. (orig.)

  11. MRI bone marrow findings in 63 patients with type I Gaucher's disease

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    Poll, L.W. [Berufsgenossenschaftliche Unfallklinik Duisburg GmbH (Germany). Abt. Radiologie; Willers, R. [Duesseldorf Univ. (Germany). Zentrum fuer Information, Kommunikation und Medientechnologie; Haeussinger, D. [Universitaetsklinikum Duesseldorf (Germany). Klinik fuer Gastroenterologie, Hepatologie und Infektiologie; Moedder, U. [Universitaetsklinikum Duesseldorf (Germany). Inst. fuer Radiologie; Dahl, S. vom [St.-Franziskus-Hospital Koeln, Akademisches Lehrkrankenhaus der Koeln Univ. (Germany). Klinik fuer Innere Medizin.

    2010-11-15

    Purpose: To determine whether MR bone marrow findings in Gaucher patients may help to identify patients at high risk of developing severe Gaucher bone complications exemplified by avascular necrosis (AVN) of the femoral head. Materials and Methods: MR images were obtained in 63 Type I Gaucher patients through a standard protocol using coronal T1 and T2-weighted sequences of the lower extremities. The location and extent of infiltrated marrow was established using a semi-quantitative MRI scoring method (Duesseldorf Gaucher score, DGS) and the morphological pattern of bone marrow involvement determined (whether homogeneous type A or non-homogeneous type B). The active marrow process with bone edema and AVN of the femoral head were also analyzed. Results: Bone marrow involvement was observed in femoral sites more than in tibial sites. A high DGS was significantly correlated with type B morphology and femoral AVN (both p < 0.0001). Splenectomized patients showed a significantly higher Duesseldorf Gaucher score and type B morphology than non-splenectomized patients (both p < 0.05). AVN was seen in 46 % of patients with type B morphology versus 3 % in type A morphology (p < 0.0001). DGS and morphology of bone marrow involvement were not significantly correlated with active marrow processes. Conclusion: Type B marrow morphology and extensive marrow packing were significantly associated with AVN of the femoral head (both p < 0.0001). These patterns are considered predictive and may be employed in a disease management context to alert physicians to the need for urgent therapeutic measures. (orig.)

  12. Imaging features of spinal osteoid osteoma with emphasis on MRI findings

    International Nuclear Information System (INIS)

    A retrospective evaluation of the imaging of 13 patients with a diagnosis of osteoid osteoma (OO) of the spine was undertaken. Available imaging included radiographs (n=10), computed tomography (CT) (n=13), bone scintigraphy (n=5) and magnetic resonance imaging (MRI) (n=13). MRI features evaluated were pattern of neural arch and vertebral body oedema and the presence of an identifiable nidus. MRI features were correlated with other available imaging. There were seven males and six females with an age range of 8-59 years. On radiographs, scoliosis was present in ten and a sclerotic pedicle in nine patients. Focal increased uptake on bone scintigraphy consistent with OO was seen in all five patients where scintigraphy was available. On CT, a nidus was identified in all patients and reactive sclerosis was seen in 12. MRI demonstrated the nidus in eight patients and unilateral neural arch oedema with anterior extension to involve the ipsilateral posterolateral vertebral body in 11. When MRI is performed in the evaluation of back pain, the presence of unilateral neural arch oedema extending to involve the posterolateral vertebral body raises the possibility of spinal OO and should prompt CT to confirm the presence of a nidus. (orig.)

  13. Long-term MRI findings of patients with embolized cerebral aneurysms

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    Pyysalo, Liisa M.; Niskakangas, Tero T.; Oehman, Juha E. (Tampere Univ. Hospital, Dept. of Neurosurgery, Tampere (Finland)), email: liisa.pyysalo@uta.fi; Keski-Nisula, Leo H.; Kaehaerae, Veikko J. (Medical Imaging Center, Tampere (Finland))

    2011-02-15

    Background: Long-term follow-up studies after endovascular treatment for intracranial aneurysm are still rare and inconclusive. Parenchymal infarctions related to aneurysms have mostly been studied in patients with subarachnoidal hemorrhage (SAH) but infarction rates in patients with endovascularly treated unruptured aneurysms have been little studied. Purpose: To determine the frequency of permanent parenchymal lesions as detected in magnetic resonance imaging (MRI) in patients treated with endovascular coiling and to assess aneurysm-related infarctions after the initial treatment period. Material and Methods: A total of 64 patients (32 with primarily ruptured aneurysms) with 69 embolized aneurysms were examined neurologically and by MRI and magnetic resonance angiography (MRA) more than 9 years after the initial endovascular treatment. Results: A total of 14 out of 32 (44%) SAH patients and 11 (34%) patients with unruptured aneurysms had parenchymal lesions in MRI. Infarctions were detected in 10 (31%) SAH patients and the majority (9/10, 90%) of them were aneurysm-related. All aneurysm-related infarctions were detected at the acute hospitalization stage. A total of six (55%) out of 11 infarctions in patients with unruptured aneurysms were aneurysm-related and two of them appeared after the treatment period. Patients with infarction had poorer clinical outcome than patients with no ischemic lesions in MRI. Conclusion: Nineteen percent of patients with unruptured and 41% with ruptured aneurysms had aneurysmrelated parenchymal lesions in MRI. Most of these were detected during acute treatment period. Aneurysmrelated infarctions after treatment period are uncommon

  14. Long-term MRI findings of patients with embolized cerebral aneurysms

    International Nuclear Information System (INIS)

    Background: Long-term follow-up studies after endovascular treatment for intracranial aneurysm are still rare and inconclusive. Parenchymal infarctions related to aneurysms have mostly been studied in patients with subarachnoidal hemorrhage (SAH) but infarction rates in patients with endovascularly treated unruptured aneurysms have been little studied. Purpose: To determine the frequency of permanent parenchymal lesions as detected in magnetic resonance imaging (MRI) in patients treated with endovascular coiling and to assess aneurysm-related infarctions after the initial treatment period. Material and Methods: A total of 64 patients (32 with primarily ruptured aneurysms) with 69 embolized aneurysms were examined neurologically and by MRI and magnetic resonance angiography (MRA) more than 9 years after the initial endovascular treatment. Results: A total of 14 out of 32 (44%) SAH patients and 11 (34%) patients with unruptured aneurysms had parenchymal lesions in MRI. Infarctions were detected in 10 (31%) SAH patients and the majority (9/10, 90%) of them were aneurysm-related. All aneurysm-related infarctions were detected at the acute hospitalization stage. A total of six (55%) out of 11 infarctions in patients with unruptured aneurysms were aneurysm-related and two of them appeared after the treatment period. Patients with infarction had poorer clinical outcome than patients with no ischemic lesions in MRI. Conclusion: Nineteen percent of patients with unruptured and 41% with ruptured aneurysms had aneurysmrelated parenchymal lesions in MRI. Most of these were detected during acute treatment period. Aneurysmrelated infarctions after treatment period are uncommon

  15. Imaging features of spinal osteoid osteoma with emphasis on MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Harish, Srinivasan [Royal National Orthopaedic Hospital NHS Trust, Department of Radiology, Middlesex (United Kingdom); Saifuddin, Asif [Royal National Orthopaedic Hospital NHS Trust, Department of Radiology, Middlesex (United Kingdom); University College London, Institute of Orthopaedics and Musculoskeletal Sciences, London (United Kingdom)

    2005-12-01

    A retrospective evaluation of the imaging of 13 patients with a diagnosis of osteoid osteoma (OO) of the spine was undertaken. Available imaging included radiographs (n=10), computed tomography (CT) (n=13), bone scintigraphy (n=5) and magnetic resonance imaging (MRI) (n=13). MRI features evaluated were pattern of neural arch and vertebral body oedema and the presence of an identifiable nidus. MRI features were correlated with other available imaging. There were seven males and six females with an age range of 8-59 years. On radiographs, scoliosis was present in ten and a sclerotic pedicle in nine patients. Focal increased uptake on bone scintigraphy consistent with OO was seen in all five patients where scintigraphy was available. On CT, a nidus was identified in all patients and reactive sclerosis was seen in 12. MRI demonstrated the nidus in eight patients and unilateral neural arch oedema with anterior extension to involve the ipsilateral posterolateral vertebral body in 11. When MRI is performed in the evaluation of back pain, the presence of unilateral neural arch oedema extending to involve the posterolateral vertebral body raises the possibility of spinal OO and should prompt CT to confirm the presence of a nidus. (orig.)

  16. MRI findings of bilateral juvenile granulosa cell tumor of the testis in a newborn presenting as intraabdominal masses

    Energy Technology Data Exchange (ETDEWEB)

    Yikilmaz, Ali [Erciyes Medical School, Department of Radiology, Gevher Nesibe Hospital, Kayseri (Turkey); Lee, Edward Y. [Children' s Hospital Boston and Harvard Medical School, Department of Radiology, Boston, MA (United States)

    2007-10-15

    Juvenile granulosa cell tumor (JGCT) of the testis is a rare benign tumor that typically presents as a relatively small (<2 cm) unilateral scrotal mass in neonates or infants. Bilateral JGCT of the testes presenting as large intraabdominal masses in the neonate is very rare. Utilizing preoperative MRI findings, we report a rare case of bilateral JGCT of the testes presenting as large multiseptated abdominal masses originating from undescended intraabdominal testes in a neonate. (orig.)

  17. Ossifying renal tumor of infancy: findings at ultrasound, CT and MRI

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Hwan; Choi, Young Hun; Kim, Woo Sun; Cheon, Jung-Eun [Seoul National University College of Medicine, Department of Radiology, Seoul (Korea, Republic of); Seoul National University Medical Research Center, The Institute of Radiation Medicine, Seoul (Korea, Republic of); Moon, Kyung Chul [Seoul National University College of Medicine, Department of Pathology, Seoul (Korea, Republic of)

    2014-05-15

    A 4-month-old boy presented with persistent gross hematuria. At ultrasonography, a 3.5-cm echogenic mass with posterior shadowing and tumor vascularity was detected within the right renal pelvis. Precontrast CT showed a slightly hyperattenuating mass in the renal pelvis. At MRI the mass was heterogeneously hypointense on T2-weighted images and isointense on T1-weighted images. Contrast-enhanced CT and MRI both revealed peripheral enhancement of the mass. A histological diagnosis of ossifying renal tumor of infancy was made after open pyelostomy and tumor enucleation. We suggest that ossifying renal tumor of infancy should be considered when a mass with posterior acoustic shadowing and tumor vascularity on US, hyperattenuation on precontrast CT and hypointensity on T2-weighted MRI is seen within the renal pelvis of an infant with hematuria. (orig.)

  18. MRI findings in patients with vertigo and dizziness possibly arising from vertebrobasilar insufficiency

    International Nuclear Information System (INIS)

    In order to evaluate diagnostic usefulness of MRI in vertebrobasilar insufficiency (VBI), we performed magnetic resonance imaging (MRI) and MR angiography (MRA) in 90 patients presenting vertigo and dizziness as an initial and cardinal complaints. High signals observed by T2-weighted imaging in the basal ganglia (44.4%) or pontine base (48.9%) were more frequently seen in the possible VBI group than in the controls (p<0.001). The electronystagmographical abnormalities were commonly observed in the patients with a high signal in the patients with a high signal in the pontine base, reflecting diffuse ischemic lesion in the territory of the vertebrobasilar system. Vertebral artery asymmetry (45.6%) or basilar artery twisting (41.1%) as shown by MRA was also significantly more frequent in the patients than in the controls (p<0.05). In conclusion, MRI and MRA were considered to be useful in making a clinical diagnosis of VBI in such patients. (author)

  19. Cervical mycotic aneurysm in an infant. MRI findings and endovascular treatment

    International Nuclear Information System (INIS)

    A case of cervical mycotic aneurysm in a 6-month-old infant is presented. Eight days after birth the preterm newborn had a perforated necrotizing enterocolitis. Treatment included abdominal percutaneous drainage and surgery. Hemo cultures grew staphylococcus aureus methicillin resistant. Antibiotic therapy was indicated with a favorable evolution. Five months later the infant showed a lateral cervical mass nad hemorrhagic fluid in her right external auditory canal. Ultrasound and MRI were performed. MRI demonstrated a heterogeneous fluid-containing neck mass, similar in appearance to a parapharyngeal hematoma, with flow void sign. Digital substraction angiography (DSA) was performed to highlight the vascular anatomy demonstrating a mycotic aneurysm adjacent to the ascendent pharyngeal artery. The endovascular treatment with Histoacryl-Lipiodol was successful without any technical or neurological complications. Mycotic aneurysm is a very rare, but potentially fatal complication in infants. In our case report, MRI and DSA provided an accurate diagnosis leading to a rapid endovascular therapy. (author)

  20. Relationship between child epilepsy and MRI findings in von Recklinghausen Neurofibromatosis (NF 1)

    International Nuclear Information System (INIS)

    Fourteen children meeting the NIH consensus diagnostic criteria for NF 1 were evaluated at the Department of Pediatrics, Himeji Red Cross Hospital. MRI and EEG were examined in all patients, respectively. Four of 14 patients had a history of epilepsy, two had suffered West syndrome, one had complex partial seizures and one had secondary generalized partial epilepsy. Seven (50%) of 14 patients showed abnormal MRI; three (75%) of 4 patients with epilepsy and four (40%) of 10 patients with epilepsy showed low intensity on T1-weighted images and hyperintensity on T2-weighted images in the globus pallidus and brain stem. These results suggest that children with NF 1 have a spectrum of MRI abnormalities, irrespective of existence of epilepsy. (author)

  1. Patients with liver FNH and HCC patients with negative AFP: plain and dynamic enhanced MRI and CT findings

    Directory of Open Access Journals (Sweden)

    LI Mingtong

    2015-05-01

    Full Text Available ObjectiveTo investigate plain and dynamic enhanced magnetic resonance imaging (MRI and computed tomography (CT findings in patients with focal nodular hyperplasia (FNH of the liver and hepatocellular carcinoma (HCC patients with negative alpha-fetoprotein (AFP. MethodsA statistical analysis was performed on the clinical data of 124 cases of liver tumor admitted to Beijing Miyun County Hospital from April 2012 to April 2014. ResultsFifty-five of the 74 patients with FNH underwent CT examination, among whom 38 patients received three-phase dynamic enhanced scan and 16 received only plain scan; 62 cases had plain and enhanced MRI with the application of contrast agent Gd-BOPTA in 42 patients. Among the 50 HCC patients with negative AFP, CT examination was performed in 40 and 10 only had plain scan; 46 patients received plain and enhanced MRI with the use of contrast agent Gd-BOPTA in 30. Delayed scan after 1-2 h demonstrated low signal in 30 lesions of the 30 cases. ConclusionFor patients with liver FNH and AFP-negative HCC patients, their plain and dynamic enhanced MRI and CT scan have respective characteristics. A combination of multiple examination methods can significantly improve diagnostic yield of the two diseases.

  2. Correlation between preprocedural MRI findings and the clinical effects of percutaneous vertebroplasty in osteoporotic vertebral compression fractures

    International Nuclear Information System (INIS)

    Objective: to analyze the signal characteristics of preprocedural MRI, to compare the pre-and-post procedural clinical outcomes and to discuss the relationship between preprocedural MRI findings and postprocedural clinical effect of percutaneous vertebroplasty (PVP) therapy in patients with osteoporotic vertebral compression fractures. Methods: PVP procedures were carried out in a total of 52 consecutive patients with 116 compression fractures. The clinical data and the imaging materials were retrospective analyzed. According to the degree and extent of marrow edema demonstrated on sagittal MRI, the patients were divided into three groups: group A, having partial bone marrow edema; group B, showing complete bone marrow edema;and group C having no bone marrow edema. By using independent-samples t-test and paired-samples t-test, the preprocedural and postprocedural pain degree and movement dysfunction severity, which were assessed by means of visual analog scale (VAS) and Oswestry disability index(ODI) respectively, were compared between three groups. The occurrence of complications was observed. Results: After PVP, all patients showed significant relief of pain and obvious improvement of daily activity function (P0.05). Conclusion: PVP is an effective treatment for osteoporotic vertebral compression fractures with or without bone marrow edema. MRI signal characteristics can predict the therapeutic effect of PVP to a certain degree. And the more extensive the bone marrow edema pattern is, the greater pain relief will be expected. (authors)

  3. Cine MR imaging of the optic nerves

    International Nuclear Information System (INIS)

    The purpose of this paper is to evaluate the advantage of cine MR imaging for optic nerve exploration. At 1.5 T, 15 patients with muscular, traumatic, neoplastic, and inflammatory orbital lesions and 25 volunteers underwent cine MR imaging with a special eye movement procedure. The angular succession of axial and vertical gaze positions has been studied. Cine MR imaging enables evaluation of orbital anatomy, demonstration of segmental mobilities, and detection of small abnormalities involving the optic nerve and sheaths. The authors conclude that ultrafast cine MR imaging offers a new investigative field for studying ocular motor and visual disturbances

  4. The "Dot in Circle" Sign on MRI in Maduramycosis: A Characteristic Finding

    Directory of Open Access Journals (Sweden)

    Vikash Jain

    2012-01-01

    Full Text Available Mycetoma or Maduramycosis is a localized chronic suppurative infection characterized by exuberant granulation tissue, discharging sinuses, and bone involvement later in the course of the disease. Early clinical diagnosis before the appearance of sinuses and grains (aggregates of organism surrounded by granulation tissue, which are discharged from the draining sinuses is difficult. Delay in diagnosis may lead to amputation of the affected part. Definitive diagnosis is through biopsy and microbiological examination. However, at times diagnosis may still be difficult. The recently described "dot in circle" sign on magnetic resonance imaging (MRI is easy to recognize and highly specific. We present a case of mycetoma foot with characteristic MRI features.

  5. Pain following double-bundle anterior cruciate ligament reconstruction: Correlation with morphological graft findings and dynamic contrast-enhanced MRI

    International Nuclear Information System (INIS)

    Aim: To determine the relationship between knee pain following anterior cruciate ligament (ACL) graft placement with morphological graft findings and dynamic contrast enhancement as assessed at MRI. Material and methods: Following institutional review board approval, 37 consecutive patients with double-bundle ACL reconstruction were enrolled. Thirteen patients had pain and 24 were asymptomatic. Imaging was performed using a 1.5 T MRI machine an average of 7.6 months after surgery. Graft-related (increase signal intensity, abnormal orientation, discontinuity, cystic degeneration, anterior translation of lateral tibia, arthrofibrosis), and non-graft related causes of knee pain (meniscal tear, cartilage injury, loose bodies, and synovitis) were evaluated. During dynamic contrast enhancement analysis, peak enhancement (ePeak) was calculated by placing a region of interest at the osteoligamentous interface of each bundle. Student's t-test was used for continuous variables analysis and chi-square or Fisher's exact test was used for categorical variables analysis. Results: There was no difference between symptomatic and asymptomatic patients regarding morphological graft-related or non-graft-related causes of knee pain. For dynamic contrast enhancement analysis, symptomatic patients had significantly lower ePeak values than asymptomatic patients in the anteromedial (p = 0.008) and posterolateral (p = 0.001) bundles or when using the higher ePeak value in either bundle (p = 0.003). Conclusion: Morphological ACL graft findings as assessed at MRI could not be used to distinguish between symptomatic and asymptomatic patients. However, lower ePeak values had a significant association with knee pain. This may indicate poor neovascularization of the graft, potentially