In the CNS, there are widespread and diverse interactions between growth factors and estrogen. Here we examine the interactions of estrogen and brain-derived neurotrophic factor (BDNF), two...Full Text Available
Edema factor (EF) and CyaA are calmodulin (CaM)-activated adenylyl cyclase exotoxins involved in the pathogenesis of anthrax and whooping cough, respectively. Using spectroscopic, enzyme kinetic and...Full Text Available
/sup 125/I-Calmodulin is internalized by isolated rat renal brush border membrane vesicles (BBV) in a time, temperature and calcium dependent manner. Internalization of /sup 125/I-calmodulin into the osmotically sensitive space of BBV was distinguished from binding of the ligand to the outer BBV surface by examining the interaction of ligand and BBV at different medium osmolarities (300-1100 mosm), uptake was inversely proportional to medium osmolarity. Internalized /sup 125/I-calmodulin was intact and Western blots of solubilized BBV with /sup 125/I-calmodulin demonstrated the presence of several calmodulin-binding proteins of 143, 118, 50, 47.5, 46.5 and 35 kilodaltons which could represent potential intravesicular binding sites for the ligand. Heparin and the related glycosaminoglycan heparin sulfate both showed a dose-dependent inhibition (0.5-50 ..mu..g/ml) of /sup ...
The homologous sequences observed for many calcium binding proteins such as parvalbumin, troponin C, the myosin light chains, and calmodulin has lead to the hypothesis that these proteins have homologous...Full Text Available
In vivo effects of toxaphene on calcium pump activity in rat brain synaptosomes was studied. Male Sprague-Dawley rats were dosed with toxaphene at 0,25,50, and 100 mg/kg/day for 3 days and sacrificed 24 h after last dose. Ca/sup 2 +/-ATPase activity and /sup 45/Ca uptake were determined in brain P/sub 2/ fraction. Toxaphene inhibited both Ca/sup 2 +/-ATPase activity and /sup 45/Ca/sup 2 +/ uptake and the inhibition was dose dependent. Both substrate and Ca/sup 2 +/ activation kinetics of Ca/sup 2 +/-ATPase indicated non-competitive type of inhibition as evidenced by decreased catalytic velocity but not enzyme-substrate affinity. The inhibited Ca/sup 2 +/-ATPase activity and Ca/sup 2 +/ uptake were restored to normal level by exogenously added calmodulin which increased both velocity and affinity. The inhibition of Ca/sup 2 +/-ATPase activity and Ca/sup 2 +/ uptake and restoration by calmodulin suggests that toxaphene may impair active calcium ...
In vivo effects of toxaphene on calcium pump activity in rat brain synaptosomes was studied. Male Sprague-Dawley rats were dosed with toxaphene at 0,25,50, and 100 mg/kg/day for 3 days and sacrificed 24 h after last dose. Ca"2"+-ATPase activity and "4"5Ca uptake were determined in brain P_2 fraction. Toxaphene inhibited both Ca"2"+-ATPase activity and "4"5Ca"2"+ uptake and the inhibition was dose dependent. Both substrate and Ca"2"+ activation kinetics of Ca"2"+-ATPase indicated non-competitive type of inhibition as evidenced by decreased catalytic velocity but not enzyme-substrate affinity. The inhibited Ca"2"+-ATPase activity and Ca"2"+ uptake were restored to normal level by exogenously added calmodulin which increased both velocity and affinity. The inhibition of Ca"2"+-ATPase activity and Ca"2"+ uptake and restoration by calmodulin suggests that toxaphene may impair active calcium transport mechanisms by decreasing regulator protein ...
Benzodiazepine withdrawal anxiety is associated with potentiation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor (AMPAR) currents in hippocampal CA1 pyramidal...Full Text Available
Multiple memory systems are involved in parallel processing of spatial information during navigation. A series of studies have distinguished between hippocampus-dependent ‘spatial’ navigation,...Full Text Available
Vacuolar ion channels in guard cells play important roles during stomatal movement and are regulated by many factors including Ca2+, calmodulin, protein kinases, and phosphatases....Full Text Available
Efflux of dopamine through the dopamine transporter (DAT) is critical for the psychostimulatory properties of amphetamines, but the underlying mechanism is unclear. Here we show that Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) plays a key role in this efflux. CaMKIIalpha bound to the distal C terminus of DAT and colocalized with DAT in dopaminergic neurons. CaMKIIalpha stimulated dopamine efflux via DAT in response to amphetamine in heterologous cells and in dopaminergic neurons. CaMKIIalpha phosphorylated serines in the distal N terminus of DAT in vitro, and mutation of these serines eliminated the stimulatory effects of CaMKIIalpha. A mutation of the DAT C terminus impairing CaMKIIalpha binding also impaired amphetamine-induced dopamine efflux. An in vivo role for CaMKII was supported by chronoamperometry measurements showing reduced amphetamine-induced dopamine efflux in response to the CaMKII inhibitor KN93. Our data suggest that CaMKIIalpha binding ...
PP2B is a Ca2+/calmodulin-dependent protein phosphatase that is ubiquitously expressed in mammals. Among other actions, it is an effector mechanism in NMDA-mediated glutamate neurotransmission as well as a regulator of GSK3? and MAPK signaling cascades. Because all of these mechanisms have demonstrable roles in the control of circadian rhythyms, we hypothesized that PP2B would be a key regulator of rhythm generation and entrainment, and that through inhibition of its phosphatase activity, the circadian system would be affected by immunosuppressant drug therapy. We report here that immunosuppressant drugs (cyclosporin A, FK506) (1) block the circadian responses to light that underlie photic entrainment; (2) produce circadian phase shifts with a characteristic nonphotic profile; and (3) disr...
Calcium-activated chloride channels (CaCCs) are widely expressed in mammalian tissues, including intestinal epithelia, where they facilitate fluid secretion. Potent, selective CaCC inhibitors have not been available. We established a high-throughput screen for identification of inhibitors of a human intestinal CaCC based on inhibition of ATP/carbachol-stimulated iodide influx in HT-29 cells after lentiviral infection with the yellow fluorescent halide-sensing protein YFP-H148Q/I152L. Screening of 50,000 diverse, drug-like compounds yielded six classes of putative CaCC inhibitors, two of which, 3-acyl-2-aminothiophenes and 5-aryl-2-aminothiazoles, inhibited by >95% iodide influx in HT-29 cells in response to multiple calcium-elevating agonists, including thapsigargin, without inhibition of calcium elevation, calcium-calmodulin kinase II activation, or cystic fibrosis transmembrane conductance regulator chloride channels. These compounds also inhibited ...
Salamanders regenerate their appendages after amputation and nerves are required for this process. Experiments were designed to test the idea that one way nerves could affect blastema cell proliferation is by influencing the metabolism of extracellular matrix (ECM) components and to identify neurotrophic factors which promote blastema cell mitosis. Temporal and spatial differences of glycosaminoglycans (GAGs) synthesis is innervated and denervated limbs were examined. Hyaluronic acid (HA) was found to be the major GAG produced during the proliferative period and chondroitin sulfate during differentiation. Denervation reduced synthesis of both these components by half. Dorsal root ganglia and fibroblast growth factor (FGF), a brain-derived mitogen, similarly doubled GAG synthesis in cultured blastemas, the FGF-effect being primarily on HA production. Histochemical and autoradiographical results confirmed the biochemical data. Autoradiography of the limb tissue ...
Objectives. The purposes of this study were to test the hypothesis that vaginal douching is linked to bacterial vaginosis in both symptomatic and asymptomatic women and to identify...Full Text Available
The purpose of the present study was to examine the in vitro effects of low-dose cadmium (Cd) on developing cortical cells. The cortical cells removed from fetuses (embryonic day 15) were treated with 10 nM of Cd for 24 h. The effects of Cd on dendritic and synaptic development were immunocytochemically observed with anti-microtubule associated protein-2 (MAP2) and anti-synapsin I antibodies, respectively. Administration of Cd suppressed dendritic as well as synaptic development at 10 nM. By two-dimensional gel electrophoresis and liquid chromatography-tandem mass spectrometric (LC/MS/MS) analysis, we identified three proteins with different expression after Cd-treatment; dihydropyrimidinase-related protein 2 (DRP-2/CRMP-2), 14-3-3-epsillon and calmodulin (CaM). Though the number of identified proteins was small, these proteins are known to be involved in neuronal development. The present study demonstrated the morphological effects as well as affected proteins in ...
Cell extracts of the thermophile Clostridium thermohydrosulfuricum catalyzed the phosphorylation by (..gamma..-/sup 32/P)ATP of several endogenous proteins with M/sub r/s between 13,000 and 100,000. Serine and tyrosine were the main acceptors. Distinct substrate proteins were found in the soluble (e.g., proteins p66, p63, and p53 of M/sub r/s 66,000, 63,000, and 53,000, respectively) and particulate (p76 and p30) fractions, both of which contained protein kinase and phosphatase activity. The soluble fraction suppressed the phosphorylation of particulate proteins and contained a protein kinase inhibitor. Phosphorylation of p53 was promoted by 10..mu..M fructose 1,6-bisphosphate or glucose 1,6-bisphosphate and suppressed by hexose monophosphates, whereas p30 and p13 were suppressed by 5 ..mu..M brain (but not spinach) calmodulin. Polyamines, including the odd polyamines characteristic of thermophiles, modulated the labeling of most of the phosphoproteins. Apart from ...
The role of intracellular Ca2+ (Ca2+i) on hematopoiesis was investigated in long term bone marrow cultures using cytokines and agonists of P2 receptors. Cytokines interleukin 3 and granulocyte/macrophage colony stimulator factor promoted a modest increase in Ca2+i concentration ([Ca2+]i) with activation of phospholipase Cgamma, MEK1/2, and Ca2+/calmodulin kinase II. Involvement of protein kinase C was restricted to stimulation with interleukin 3. In addition, these cytokines promoted proliferation (20 times) and an increase in the Gr-1(-)Mac-1+ population with participation of gap junctions (GJ). Nevertheless ATP, ADP, and UTP promoted a large increase in [Ca2+]i, moderate proliferation (6 times), a reduction in the primitive Gr-1(-)Mac-1(-)c-Kit+ population, and differentiation into macrophages without participation of GJ. It is likely that Ca2+i participates as a regulator of hematopoietic signaling: moderate increases in [Ca2+]i would be related to ...
For a word w in the braid group on n-strands, we denote by T_w the corresponding transverse braid in the rotational symmetric tight contact structure on S^3. We exhibit a map on link Floer homology which sends the transverse invariant associated to T_{ws_i} to that associated to T_w, where s_i is one of the standard generators of B_n. This gives rise to a "comultiplication" map on link Floer homology. We use this to generate infinitely many new examples of prime topological link types which are not transversely simple.
The Gigabit Link Interface Board (GLIB) is an evaluation platform and an easy entry point for users of high speed optical links in high energy physics experiments. Its intended use ranges from optical link evaluation in the laboratory to control, triggering and data acquisition from remote modules in beam or irradiation tests. The GLIB is an FPGA-based Advanced Mezzanine Card (AMC) conceived to serve a small and simple system residing either inside a Micro Telecommunications Computing Architecture (?TCA) crate, or on a bench with a link to a PC. This paper presents the architecture of the GLIB, its features as well as examples of its use in different setups.
In X-linked nephrogenic diabetes insipidus (NDI) the urine of male patients is not concentrated after the administration of the antidiuretic hormone arginine-vasopressin. This disease is due to mutations...Full Text Available
A monoclonal antibody raised against carboxyl-linked IAA was used in Western blot analysis of storage proteins from kernels of Avena sativa, Pennisetum americanum, Sorghum bicolor,...Full Text Available
The effect of reinforcement in the cross-linked poly(propylene fumarate-co-caprolactone diol) thermoset composites based on Kevlar fibres and hydroxyapatite was studied. Cross-linked poly(propylene...Full Text Available
Cilia are important cellular structures that have been implicated in a variety of signaling cascades. In this review, we discuss the current evidence for and against a link between cilia and both the...Full Text Available
Tutorial on digital libraries. Site also contains links to other reference materials on digital libraries as well as links to courses on the subject. Keywords: Information Systems - Information Systems Applications, Information Storage and Retrieval, Database Management, multimedia
A computer program, RISK-XLR, which calculates genetic risk for carrier status of a Mendelian X-linked recessive condition has been written for the Macintosh series of microcomputers. The program,...Full Text Available
DNA interstrand cross-links (ICLs) are critical cytotoxic lesions produced by cancer chemotherapeutic agents such as the nitrogen mustards and platinum drugs; however, the exact mechanism of ICL-induced...Full Text Available
... is known as "reproductive cloning." The Link to Stem Cell Research Stem cell research and research cloning are closely linked. Scientists in ... to arrive at a position on cloning and stem cell research. Many nations, including the UK, China, and South ...
The recombinant product (rK39) of the 39-amino-acid repeats encoded by a kinesin-like protein-encoding gene of Leishmania chagasi was evaluated by enzyme-linked immunosorbent assay...Full Text Available
In the present study we have used the alkaline elution technique to study the effect of misonidazole (MISO) on the initial amount of DNA cross-linking in various normal and neoplastic tissues of C3H...Full Text Available
We modified an existing enzyme-linked immunosorbent assay (ELISA) to be able to use new spectrophotometers which can measure the rate of color development in microtiter wells. This new kinetic-based...Full Text Available
Species of the large family Orchidaceae display a spectacular array of adaptations and rapid speciations that are linked to several innovative features, including specialized pollination syndromes,...Full Text Available
The concentration of free indoleacetic acid (IAA) is high in cotton (Gossypium hirsutum L.) fruiting forms before anthesis, but is low at and for a few days after anthesis. Amide-linked...Full Text Available
...2 Resource type: documents Mesothelioma Information HON-code certified resource, covering the main aspects of asbestos exposure: diagnosis, diseases caused by asbestos, treatment options, prevention and legal options. Diagrams are included in articles, and links are provided to the references used. Also contains a listing of ...
A potent link to dairy seems to exist for three hormone-responsive glands. Acne, breast cancer and prostate cancer have all been linked epidemiologically to dairy intake. Although mechanisms postulated...Full Text Available
... due to the evolving nature of the Strategy Maps and the changing priority roles, it was decided not to link the SMSP directly with any Strategic Plans. ...
...O | P | Q | R | S | T | U | V | W | X | Y | Z 230 Christianity: general resources ...com: Christianity: General Anno Domini: Jesus Through the Centuries Bible and Homosexuality Christian Theological Research Fellowship Papers Christianity Links and Resources Directory ...Good Digital Collections Lambert's Web Links MUNDUS New Testament Gateway Omnilist of Christian Starting Points Quartz Hill School of Theology Web Library Theology Online ...com: Christianity: General Offers original articles and features about Christianity in general plus annotated links to selected relevant Internet resources, compiled by ...
Patients suffering from depression frequently display hyperactivity of the hypothalamic-pituitary-adrenal axis (HPA) resulting in elevated cortisol levels. One main symptom of this condition is anhedonia. There is evidence that exercise training can be used as a rehabilitative intervention in the treatment of depressive disorders. In this scenario, the aim of the present study was to assess the effect of an aerobic exercise training protocol on the depressive-like behavior, anhedonia, induced by repeated dexamethasone administration. The study was carried out on adult male Wistar rats randomly divided into four groups: the "control group" (C), "exercise group" (E), "dexamethasone group" (D) and the "dexamethasone plus exercise group" (DE). The exercise training consisted of swimming (1 h/d, 5 d/wk) for 3 weeks, with an overload of 5% of the rat body weight. Every day rats were injected with either dexamethasone (D/DE) or saline solution (C/E). Proper positive controls, using ...
The extracellular matrix (ECM) of the distal tissues in a newt limb stump is completely reorganized in the 2-3-week period following amputation. In view of numerous in vitro studies showing that extracellular material influences cellular migration and proliferation, it is likely that the changes in the limb's ECM are important activities in the process leading to regeneration of such limbs. Using biochemical, autoradiographic, and histochemical techniques we studied temporal and spatial differences in the synthesis of glycosaminoglycans (GAGs) during the early, nerve-dependent phase of limb regeneration. Hyaluronic acid synthesis began with the onset of tissue dedifferentiation, became maximal within 1 weeks, and continued throughout the period of active cell proliferation. Chondroitin sulfate synthesis began somewhat later, increased steadily, and reached very high levels during chondrogenesis. During the first 10 days after amputation, distributions of sulfated and nonsulfated GAGs ...
Middleware deployed to help TCP performance over links with large ... Boeing Connex (Ku-Band); INMARSAT Swift 64; TrackNet" 2.0 (Ku-Band); G2.5/G3/G4. General ... Incremental deployment may be difficult; High Link budgets; Link Delay ...
Regularities in the radiation cross-linking of low-density polyethylene under various conditions of ..gamma..-irradiation were studied. It is shown that at the 0.5 GPa pressure and 450 K the gel formation is initiated at doses of about 1 kGy, i.e. at doses 10 times as low as compared to normal conditions. Abnormally high rate of radiation cross-linking at high temperature and high pressure is an evidence of changes in the mechanism of polyethylene, radiation cross-linking, i.e. of the process transition from nonchain to chain conditions. Decrease in the potential barriers of macroradical reactions with macromolecules is the most probable reason of change in the polymer cross-linking nature.
When a shortened enzymatic version of the Tetrahymena self-splicing intervening sequence (IVS) RNA is placed under catalytic conditions and irradiated at 254 nm, a covalent cross-link forms with high efficiency. The position of the cross-link was mapped by using three independent methods: RNase H digestion, primer extension with reverse transcriptase, and partial hydrolysis of end-labeled RNA. The cross-link is chemically unusual in that it joins two adenosines, A57 and A95. Formation of this cross-link depends upon the identity and concentration of divalent cations present and upon heat-cool renaturation of the IVS in a manner that parallels conditions required for optimal catalytic activity. Furthermore, cross-linking requires the presence of sequences within the core structure, which is conserved among group I intervening sequences and necessary for catalytic activity. Together ...
The sterile insect release technique can often be improved by removal of females before release. Rearing efficiencies can also be increased if removal of the females occurs at early developmental stages. In order to begin to develop genetic sexing strains for the pink bollworm, Pectinophora gossypiella (Saunders), it was necessary to determine the best dosage of radiation for induction of viable sex linked recessive lethal mutations and to see if stocks containing induced sex linked lethals could be maintained in culture. Sex linked recessive lethal mutations can be detected by distorted sex ratios in the progeny of treated adults. However, in the pink bollworm, highly distorted sex ratios are common even in the absence of induced mutations. Therefore, a visible sex linked trait, purple eye, was used as a marker for the untreated X-chromosomes in crosses. Thus, the presence of a recessive sex ...
We describe a clustering method for labeled link network (semantic graph) that can be used to group important nodes (highly connected nodes) with their relevant link's labels by using PARAFAC tensor decomposition. In this kind of network, the adjacency matrix can not be used to fully describe all information about the network structure. We have to expand the matrix into 3-way adjacency tensor, so that not only the information about to which nodes a node connects to but by which link's labels is also included. And by applying PARAFAC decomposition on this tensor, we get two lists, nodes and link's labels with scores attached to each node and labels, for each decomposition group. So clustering process to get the important nodes along with their relevant labels can be done simply by sorting the lists in decreasing order. To test the method, we construct labeled link network by using ...
The Astrophysics Data System (ADS) provides an extensive system of links between the literature and other on-line information. Recently, the journals of the American Astronomical Society (AAS) and a group of NASA data centers have collaborated to provide more links between on-line data obtained by space missions and the on-line journals. Authors can now specify which data sets they have used in their article. This information is used by the participants to provide the links between the literature and the data. The ADS is available at: http://ads.harvard.edu
A synthesis of scientific knowledge about petroleum biodegradation linked to uranium mineralisation is firstly done. Then the genesis of Huemul Uranium ore deposit (Malargue Town, Mendoza Province) is discussed, where Uranium ore is linked only with one type of asphaltite (there are three other types) from an oil field close by. This asphaltite type would be an efficient natural geological barrier for Uranium migration and it could be linked to a particular kind of biodegradation. The authors think that the International Wonuc Conference would be a good opportunity to discuss a way for future investigations. (author)
...BUBL LINK: Computer programming - visual basic BUBL LINK Catalogue of Internet Resources Home | Search | Subject Menus | Countries ...O | P | Q | R | S | T | U | V | W | X | Y | Z Computer programming - visual basic Titles ... Author: Microsoft Subjects: computer programming - visual basic DeweyClass: 005.133 Resource type: software SearchVB....com Subjects: computer programming - visual basic DeweyClass: 005.133 Resource type: index VB Helper Tutorials ...
All-optical envelope detection of a 5 GHz 200 Mbit/s modulated radio frequency signal is achieved using a 650 nm resonant cavity light emitting diode. Error-free transmission is achieved over a 50 m-long link of 1 mm diameter graded index polymer optical fibre (POF). The presented system has potential applications in low cost and low complexity short range wireless and wireline POF-based transmission links.
The HVDC link across the English Channel, which was brought into service in 1986, has several innovative features. Techniques used in its construction together with recent developments have consolidated the viability of HVDC links for a variety of applications. Outlines the main features of the scheme, including the benefits of interconnecting the British and French 400 kV AC power systems; integration of the UK converter system to the 400 kV AC grid; the DC submarine cables; convertor equipment (particularly the UK installation); and future HVDC developments. 6 refs.
BackgroundOxidative stress has been proposed as a mechanism linking the poor placental perfusion characteristic of preeclampsia with the clinical manifestations of...Full Text Available
Careers Business / Policy USAID: From The American People - Link to USAID Home Page Health USAID's 50th Anniversary Health Overview » Overview Technical Areas Countries...
and Vendors on the Web Bartleby.com "Great books online." Electronic Texts & Digital Libraries Links to the full text of books and other texts on the Web. Law and Politics...
This paper examines theoretically the effects that restraints on the tertiary structure of a superhelical DNA domain exert on the energetics of linking and the onset of conformational transitions. The...Full Text Available
... 4302, and to the Office of Management and Budget, Paper-work ... link coverage areas, so it is possible to receive your own ... mestic Ku-band satellite. ...
... development of SC policy within DOD, because it describes the necessary link between DOD ... strategy convolutes USG efforts to develop SC policy. ...
The spread spectrum acquisition and tracking performance for the Shuttle S-band and Ku-band communication links are analyzed and compared to test results. The S-band link requirements are more severe than those of the Ku-band links, hence, different despreader designs were developed for the two systems. The S-band despreader acquires pseudonoise code lock by examining all possible code phases in half chip steps while the Ku-band despreader acquires pseudonoise code lock by continuously sweeping a tau-jitter loop. Both despreaders employ a tau-jitter loop for code tracking. The code tracking performance is computed for the tau-jitter loop and compared to that of the more complex delay lock loop.
Education resources dealing with solar-terrestrial physics, solar effects, solar radiation, etc. Includes links to short reference papers on subjects ... ...
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A growing body of evidence in cognitive science and neuroscience points towards the existence of a deep interconnection between cognition, perception and action. According to this embodied perspective...Full Text Available
... rivers of the world, the Zaire is not an efficient transportation link because of many rapids and falls to negotiate between Kinshasa and the port city of Matadi. ...
may experience difficulty opening the Facebook page due to current HHS policy and network security that blocks access to the site. Site Map - Contact Us - Linking to USPHS.gov -...
ObjectiveTo assess familial links in fat stereotypes and predictors of stereotypes among girls and their parents.Research Methods and...Full Text Available
BackgroundPrior research links optimism to physical health, but the strength of the association has not been systematically evaluated.PurposeFull Text Available
Mangroves are disappearing rapidly worldwide despite their well documented biodiversity and the ecosystem services they provide. Failure to link ecological processes and their societal benefits has...Full Text Available
Hyperglycemia frequently occurs with acute medical illness, especially among patients with cardiovascular disease, and has been linked to increased morbidity and mortality in critically ill patients....Full Text Available
Invasive fungal infections can be devastating, particularly in immunocompromised patients, and difficult to treat with systemic drugs. Furthermore, systemic administration of those medications...Full Text Available
Skip Over Navigation Links U.S. Department of Health & Human Services National Institutes of Health NIH...Turning Discovery into Health For Employees Staff Directory En Español...
PurposeHealth information technology (HIT) and physician career satisfaction are associated with higher-quality medical care. However, the link between HIT and physician...Full Text Available
Space Network Ku-band service. ... Completed GLAST mission schedule and budget assessment .... Utilize Ku band SN link (TDRSS) for science data return ...
We used neuropsychological tasks to investigate integrity of brain circuits linking orbitofrontal cortex and amygdala (orbitofrontal-amygdala), and dorsolateral prefrontal cortex and hippocampus...Full Text Available
Background and objectives: Despite potential significance of fatigue and its underlying components in the occurrence of cardiovascular diseases, epidemiologic data showing the link are virtually limited....Full Text Available
BackgroundEnzyme-linked immunosorbent assay (ELISA) is a standard immunoassay to estimate a protein's concentration in a sample. Deploying ELISA in a microarray format permits simultaneous...Full Text Available
on this technology has beenproposedas a payload on SpaceStation Freedom to be launched in the near future [1]. Direct detection 4-ary pulse position modula- ...
... Ward, William E. Brigadier General, Assistant Division Commander (Support), 82nd Airborne Division, Fort Bragg, North Carolina, Chief, Office of ...
... This series of contingency readiness exercises began in July when a company of soldiers from the Army's 82nd Airborne Division deployed to Haiti ...
A design is proposed for forming the rear screen of a chamber firebox at the point of aerodynamic projection and a design for attaching the pipes of the aerodynamic projection using girders linked with the screen by hinges and movable connections.
Network tomography aims at inferring internal network characteristics based on measurements at the edge of the network. In loss tomography, in particular, the characteristic of interest is the loss rate of individual links. There is a significant body of work dedicated to this problem using multicast and/or unicast end-to-end probes. Independently, recent advances in network coding have shown that there are several advantages from allowing intermediate nodes to process and combine, in addition to just forward, packets. In this paper, we pose the problem of loss tomography in networks that have network coding capabilities. We design a framework for estimating link loss rates, which leverages network coding capabilities and we show that it improves several aspects of tomography, including the identifiability of links, the tradeoff between estimation accuracy and bandwidth efficiency, and the complexity of probe path ...
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Pages 184-197: Understanding Personal Change in a Women’s Faith-Based Transitional Center/title link ...titleUnderstanding Personal Change in a Women’s Faith-Based Transitional Center/dc:title
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Ozsvath and Szabo show that there is a spectral sequence whose E^2 term is the reduced Khovanov homology of L, and which converges to the Heegaard Floer homology of the (orientation reversed) branched double cover of S^3 along L. We prove that the E^k term of this spectral sequence is an invariant of the link L when k>2. If L is a transverse link, then we show that Plamenevskaya's transverse invariant gives rise to a transverse invariant of L in each of these higher terms.
We have used intramolecular cross-linking, MS, and sequence threading to rapidly identify the fold of a model protein, bovine basic fibroblast growth factor (FGF)-2. Its tertiary structure was probed...Full Text Available
We report the presence of oligosaccharide structures on a glutamine residue present in the VL domain sequence of a recombinant human IgG2 molecule. Residue Gln-106, present in the QGT sequence...Full Text Available
DescriptionThis application is a request for Bridge Link funds to support studies in order to develop a full proposal under the Link Sustainable Livestock Scheme in collaboration with Dr Nigel Scollan of IGER. The hypothesis being examined is that the poor performance of some ruminants is due to poor nutrition at strategic time points during the animal's development. The initial hypothesis will be tested in sheep and the results from this will be used to develop the full proposal. Excessive fat in ruminan [continued...
An enzyme-linked immunosorbent assay was used to compare Brucella melitensis major outer membrane proteins (MOMP) and whole-cell heat-killed antigens (HK) in measuring antibrucella immunoglobulin G...Full Text Available
32P-Postlabeling analysis and enzyme-linked immunosorbent assay (ELISA) have been used to detect DNA adducts in peripheral blood lymphocytes from primary aluminum production plant workers who were exposed...Full Text Available
Enzyme-linked immunosorbent assay (ELISA), indirect immunofluorescent-antibody assay (IFA), and Western immunoblot were used to test serum samples from 128 dogs for the presence of antibody to Borrelia...Full Text Available
BackgroundATRX is a tightly-regulated multifunctional protein with crucial roles in mammalian development. Mutations in the ATRX gene cause ATR-X syndrome, an X-linked...Full Text Available
Amide-linked indole-3-acetic acid (IAA) conjugates constitute approximately 90% of the IAA pool in the dicot Arabidopsis, whereas ester-linked conjugates and free IAA account for approximately...Full Text Available
In this article, equations of motion of a manipulator are derived after consideration of the characteristics of the driving source. By considering a collision between a link and an object, and considering the active motion to absorb the kinetic energy of the object, the trajectories for saving energy are calculated by the iterative dynamic programming (IDP) method. The dynamic characteristics of manipulator control based on the trajectory for saving energy are also analyzed theoretically and investigated experimentally.
Significant recent writings have suggested strong parallels and actual links between the historical legal architectures of Canadian Aboriginal policy and South African apartheid. This article's further probing of these claims shows them to be very doubtful. At the same time, some more limited legal parallels between the two systems shows the importance of undertaking further analysis of the transmission and exchange of legal ideas and norms within the Commonwealth order.
The PSDE/SAT-2 multimission satellite designed to offer a flight opportunity to different experimental communication payloads and verify the feasibility of advanced space technologies is described. It was conceived for expriment in the framework of the European DRS (Data Relay Satellite) program thus providing intersatellite and interorbit communication links, but also experimental and preoperative services. Payloads include optical communication single access payload (LSA); S-Band single access payload; S-Band multiple access payload; land mobile experimental payload; navigation payload; 40/50 GHz communication payload; and millimeter wave propagation payload. The orbital slot and interference analysis identified a limited number of orbital positions for the mission interleaved between Eutelsat satellites (i.e., 14 deg 30 min E and 17 deg 30 min E). A coordination is required in Ku-Band with Eutelsat satellites and in Ka-Band with ITALSAT (Italy) and TOR-12 (USSR) ...
Since chlordecone (Kepone, CD) interferes with cardiac Na{sup +} ion translocases, we have studied CD effects on cardiac SR calcium pump activity. SR was isolated from heart ventricles of male Sprague-Dawley rats. Cardiac SR Ca{sup 2+}-ATPase, {sup 45}Ca-uptake and cAMP as well as calmodulin (CaM) dependent protein phosphorylation were measured. Ca{sup 2+}-ATPase was differentiated into low affinity and high affinity forms by measuring the activity using 50 and 0.7 {mu}M free Ca{sup 2+} respectively. CD in vitro inhibited {sup 45}Ca-uptake by SR in a concentration dependent manner with an IC50 value of 7 {mu}M and SR {sup 45}Ca-uptake was totally inhibited at 20-30 {mu}M CD. In agreement with this, both high affinity and low affinity Ca{sup 2+}-ATPases, which are involved in Ca{sup 2+} transport across membranes, were also inhibited by CD in a concentration dependent manner with IC50 values of 0.7 and 3.2 {mu}M respectively. Both Ca{sup 2+}-ATPase and {sup ...
The aim of this study was to qualitatively and quantitatively study MR artifacts of various stents on the basis of in vitro experiments. We were particularly interested whether sequence type and orientation of the stent with respect to the static magnetic field influences the artifact. We examined 18 stents of different material (nitinol, stainless steel, cobalt alloy), different design of the stent meshes (AccuLink, OmniLink, DynaLink, Xact, Protoge, Wallstent Monorail), different diameter (5-10 mm) and different length (18-58 mm) with a turbo spin echo (TSE), a 2D-fast low angle shot (FLASH) and a 3D-FLASH sequence. The MR images were examined qualitatively with respect to possible artifacts. Furthermore we examined the MR data quantitatively: The contrast-noise-ratio (CNR) was determined both within the stent and outside (within the tube); based on these values we calculated the transparency factor P, furthermore we ...
In this article based on extensive ethnographic interviewing of eighty-six Japanese adults, I analyze the different ways in which they understand life after death, and consider the societal implications of their views. I examine senses of life after death as based in communion with departed family members as linked to practices of ancestor veneration and ideologies of Japaneseness. I consider heaven/hell or reincarnation as linked, through the idea of impartial judgment of the individual, to meritocracy and the examination system. I examine agnosticism and relativism in senses of life after death as linked to the idea that individual freedom of choice may exist in the next world if not necessarily within the constraints of this Japanese world. I examine disbelief in any realm beyond the gr...
BackgroundA common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs requires...Full Text Available
BackgroundHarbour porpoises Phocoena phocoena from the southern North Sea are known to display high levels of Zn and Hg in their tissues linked to their nutritional...Full Text Available
Growing evidence suggests the Wnt family of secreted glycoproteins and their associated signaling pathways, linked to development, are recapitulated during wound repair and regeneration events. However,...Full Text Available
Genetic studies of nicotine addiction in mice have utilized the oral self-administration model. However, it is unclear if strain differences in nicotine consumption are influenced by variation in bitter...Full Text Available
Amidination of aldolase, glyceraldehyde-3-phosphate dehydrogenase, tryptophan synthetase B protein, L-arabinose isomerase, and the catalytic subunit of E. coli aspartate transcarbamylase...Full Text Available
Ophthalmologic abnormalities have been described in patients with dementia, but the extent to which poor vision and treatment for visual disorders affect cognitive decline is not well defined. Linked...Full Text Available
In a "nutrition transition", the consumption of foods high in fats and sweeteners is increasing throughout the developing world. The transition, implicated in the rapid rise of obesity and diet-related...Full Text Available
This article addresses the connection of cogeneration plants to the utility system. The article provides examples for use in illustrating the problems that must be overcome and the solution chosen. These illustrations include high voltage utility connection, multiple connections to the utility at one location, and dealing with losses and obstructions.
Cytosine methylation in DNA is a major epigenetic signal, and plays a central role in propagating chromatin status during cell division. However the mechanistic links between DNA methylation...Full Text Available
A new analysis is presented which links real volume fractions, relaxation rates, and intracompartmental exchange rates directly with apparent volume fractions and relaxation rates obtained from biexponential...Full Text Available
Trypanosoma brucei contains two isoenzymes for glyceraldehyde-phosphate dehydrogenase (GAPDH); one enzyme resides in a microbody-like organelle, the glycosome, the other one is found in the cytosol....Full Text Available
Materials and MethodsThe genomic effects of tumor-endothelial interactions in cancer are not yet well characterized. To study this interaction in breast...Full Text Available
ObjectivesUse of prescription opioids for chronic pain is increasing, as is abuse of these medications, though the nature of the link between these trends is unclear....Full Text Available
Different models have been proposed that link the tubulin heterodimer nucleotide content and the role of GTP hydrolysis with microtubule assembly and dynamics. Here we compare the thermodynamics of...Full Text Available
Lists of reportable conditions and case definitions are important tools for epidemiologic surveillance. As part of an initiative to encourage occupational disease surveillance systems linked to intervention...Full Text Available
Although recent data established that a specific very-long-chain fatty acyl-CoA synthetase is defective in X-linked adrenoleukodystrophy (ALD), the ALD gene is still unidentified. The ALD locus has...Full Text Available
BackgroundActivation of the signal transducer and activator of transcription 3 (STAT3) within antigen presenting cells (APCs) is linked to abnormal APCs differentiation and function....Full Text Available
~4-5 times per day through a 40 Mbps Ku-band TDRSS link, while commands are uplinked on a 4 ..... During Phase 2 the budget will be ~$6M/year. Accounting ...
BackgroundThe link between maternal factors and birth outcomes is well established. Substantial changes in society and medical care over time have influenced women's reproductive...Full Text Available
OPERATE AT SOUTH POLE WINTER AMBIENTS, GIVEN THE PROJECT'S BUDGET AND TIME LINES . ... 17 MAXIMUM ELECTRICAL LENGHT CONSTRAINED BY Ku-BAND AT 50 FT. ... A MAXIMUM LENGTH OF 50 FEET HAS BEEN SPECIFIED BY THE SYSTEM LINK CALCULATIONS TO ...
The advanced technologies of Ka-Band systems such as high gain spot .... sometimes used based on link requirements for a specific application. .... received at NASA LeRC from a Ku-band satellite and retransmitted to the USAT at Ka-Band. .... and to the Office of Management and Budget, Paperwork Reduction Project ...
BackgroundThe molecular mechanisms of variations in individual longevity are not well understood, even though longevity can be increased substantially by means of diverse experimental...Full Text Available
...A directory of University social media accounts, including Facebook, Twitter and YouTube facebook, twitter, blog Social media - Social media, The ... Key: Facebook, Twitter, YouTube, Blog, LinkedIn, Flickr Missed you out? If you'd like to be included on this ...
Previous studies have been conducted in gene expression profiling to identify groups of genes that characterize the colorectal carcinoma disease. Despite the success of previous attempts to identify...Full Text Available
Background:Parity has been linked to gallbladder cancer and gallstones, but the effects of other reproductive factors are less clear.Methods:We examined...Full Text Available
Apolipoprotein (apo) A-IV is a polymorphic, intestinally derived apolipoprotein that is genetically linked to and similar in structure to apoA-I, the major apolipoprotein in high density lipoproteins...Full Text Available
... 12, 2007 | Rate It Distribution and Variety of Equatorial Rain Forest , The http://www.esd.ornl.gov/projects/qen/rainfo.html (3 votes) an in depth examination of ecological patterns in rainforests from the Oak Ridge National Laboratory Added: Mar. 17, 2001 ...
Background In May 2000, AstraZeneca launched a Web service for asthma patients and health-care providers called LinkMedica, which includes an asthma diary for...Full Text Available
Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans. Though these associations are well established, evidence...Full Text Available
The introduction and survival of zoonotic bacterial pathogens in poultry farming have been linked to bacterial association with free-living protozoa. To date, however, no information is available on...Full Text Available
Young men's errors in sexual perception have been linked to sexual coercion. The current investigation sought to explicate the perceptual and decisional sources of these social perception errors,...Full Text Available
The retroviral RNA genome is dimeric, consisting of two identical strands of RNA linked near their 5′ ends by a dimer linkage structure. Previously it was shown that human foamy virus (HFV)...Full Text Available
The insulin/IGF-1 signaling (IIS) pathway is a conserved regulator of longevity, development, and metabolism. In Caenorhabditis elegans IIS involves activation of DAF-2 (insulin/IGF-1...Full Text Available
Background. The Free Radical Theory of Aging mechanistically links oxidative stress to aging. Okinawa has among the world's longest-lived populations but oxidative stress in this...Full Text Available
Link to USGS home page Results of Electrical Resistivity Data Collected near the Town of Guernsey, Platte County, Wyoming By Robert R. McDougal, Jared D. Abraham, and Robert J....
Previous studies of insect flight control have been statistical in approach, simply correlating wing kinematics with body kinematics or force production. Kinematics and forces are linked by Newtonian...Full Text Available
This report discusses the following topics on superconductivity: nonlinearities in hard superconductors such as surface impedance of a type II superconductimg half space and harmonic generation and intermodulation due to alternating transport currents; and nonlinearities in superconducting weak links such as harmonic generation by a long Josephson Junction in a superconducting slab.
The CNS can exhibit features of inflammation in response to injury, infection or disease, whereby resident cells generate inflammatory mediators, including cytokines, prostaglandins, free radicals and...Full Text Available
The developing Integrated Academic Information System (IAIMS) at Columbia-Presbyterian Medical Center provides data sharing links between two separate corporate entities, namely Columbia University...Full Text Available
...links ensure all of our managed accommodation is easily accessible to both campus sites and our special student arrangement makes travelling on the Metro rapid transit system easily affordable. Our halls are comfortable and they are very reasonable. Download the rents table here Rents 2009-2010 Students living in ...
Myelin-associated glycoprotein (MAG) has been implicated in inhibition of nerve regeneration in the CNS. This results from interactions between MAG and the Nogo receptor and gangliosides on...Full Text Available
Neuroblasts in the developing Drosophila CNS asymmetrically localize the cell fate determinants Numb and Prospero as well as prospero RNA to the basal cortex during...Full Text Available
Antibodies to myelin oligodendrocyte glycoprotein (MOG) have been implicated in Multiple Sclerosis demyelination through activation of complement and/or macrophage-effector processes. We presented...Full Text Available
Benzidine-based azo dyes are proven mutagens and have been linked to bladder cancer. Previous studies have indicated that their initial reduction is the result of the azo reductase activity of the intestinal...Full Text Available
125 Years of Science for America - 1879 to 2004 link to Western Coastal and Marine Geology website U.S. Geological Survey Professional Paper 1687 Marine Geology and Earthquake...
The identification of predictive biomarkers is at the core of modern toxicology. So far, a number of approaches have been proposed. These rely on statistical inference of toxicity response from either...Full Text Available
Obesity and metabolic syndrome result from excess calorie intake and genetic predisposition and are mechanistically linked to type II diabetes and accelerated body aging; abnormal nutrient and insulin...Full Text Available
There is general consensus that climate change has contributed to the observed decline, and extinction, of many amphibian species throughout the world. ... ...
BackgroundGene expression profiling and the analysis of protein-protein interaction (PPI) networks may support the identification of disease bio-markers and potential drug targets....Full Text Available
A variety of albumin polymers were prepared and tested for binding with hepatitis B surface antigen (HBsAg): synthetic polymers cross-linked by either glutaraldehyde or carbodiimide; heat-aggregated...Full Text Available
In the past, the fermentation activity of Saccharomyces cerevisiae in substrates with a high concentration of sucrose (HSuc), such as sweet bread doughs, has been linked inversely to invertase activity...Full Text Available
Damage to the anterior talofibular ligament (ATFL) and cacaneofibular ligament (CFL) during ankle sprain may be linked to the development of osteoarthritis. Altered tibiotalar kinematics have...Full Text Available
Two Brucella fractions, the murein-linked fraction PI and the murein-free fraction SF, behave as in vitro adjuvants for primary anti-sheep erythrocyte responses: added to Mishell and Dutton-type cultures...Full Text Available
The intramembrane aspartyl protease γ-secretase plays a fundamental role in several signaling pathways involved in cellular differentiation and has been linked with a variety of human diseases,...Full Text Available
There is increasing evidence for an empiric link between late-life depression and Alzheimer disease (AD). The neuropathology of AD, previously only confirmed at autopsy, may now be detectable...Full Text Available
The IFAP syndrome is a rare X-linked genetic disorder reported in nearly 40 patients. It is characterized by the triad of Ichthyosis Follicularis, Alopecia, and Photophobia from birth. Other features...Full Text Available
For many years, epidemiological studies have demonstrated a strong link between chronic hepatitis B virus (HBV) infection and the development of primary hepatocellular carcinoma (PHC). Other hepatocarcinogens...Full Text Available
World - USGS visual identity mark and link to main Web site at http://www.usgs.gov/ GEOLOGY OF THE OCOEE WHITEWATER CENTER, CHEROKEE NATIONAL FOREST Ocoee Whitewater Center logo...
We report on genetic identification of ‘whale meat’ purchased in sushi restaurants in Los Angeles, CA (USA) in October 2009 and in Seoul, South Korea in June and September 2009. Phylogenetic...Full Text Available
Drosophila neuroblasts divide asymmetrically by aligning their mitotic spindle with cortical cell polarity to generate distinct sibling cell types. Neuroblasts asymmetrically localize...Full Text Available
Multiple discrete regions at 8q24 were recently shown to contain alleles that predispose to many cancers including prostate, breast, and colon. These regions are far from any annotated gene and their...Full Text Available
This project reflected cooperation across the disciplines in the physical sciences, engineering, mathematics and computer science. The University of the Pacific served as the center for this pre-college program. The idea was to use this link as a pilot program.
This frequently-asked-questions feature provides answers about earthquakes, faults, plate tectonics, and earth structure. Maps and diagrams are provided with some answers, and links to additional information and to related topics are included.
The object of the test was to develop a method to field test the Exploding Bridgewire (EBW) System for proper functioning prior to use. Two basic designs were conceived and tested. The first design using a two element spark gap and a calibrated fuse link ...
The Japanese medaka fish Oryzias latipes has an XX/XY sex-determination system. The Y-linked sex-determination gene DMY is a duplicate of the autosomal gene DMRT1, which encodes a DM-domain-containing...Full Text Available
Forty-one Spanish families with polycystic kidney disease 1 (PKD1) were studied for evidence of linkage disequilibrium between the disease locus and six closely linked markers. Four of these loci--three...Full Text Available
Increasing evidence of links between climate change, anthropogenic stress and coral disease underscores the importance of understanding the mechanisms by which reef-building corals resist infection...Full Text Available
Chromosomal translocation, deletion, and inversion/duplication directly linked to hepatitis B virus (HBV) DNA integration occur frequently in host DNA of human hepatocellular carcinomas. To test the...Full Text Available
Linking biological samples found at a crime scene with the actual crime event represents the most important aspect of forensic investigation, together with the identification of the sample donor. While...Full Text Available
The programming of cellular networks to achieve new biological functions depends on the development of genetic tools that link the presence of a molecular signal to gene-regulatory activity. Recently,...Full Text Available
Obesity is a risk factor for stroke and neurodegenerative disease. Excess body fat has been linked to impaired glucose metabolism, insulin resistance, and impulsivity and may be a precursor to decline...Full Text Available
Recent years have seen closer links developing between general practitioners and mental health specialists. A study was undertaken in Manchester to determine the effects of a new community mental health...Full Text Available
... 03, 2001 | Rate It Lake Superior Streams http://www.lakesuperiorstreams.org/ (1 vote) interactively examine real-time water quality data from 5 ...north shore Lake Superior trout streams and learn about other streams in the region, how they \\
Social stress is prevalent in many facets of modern society. Epidemiological data suggest that stress is linked to the development of overweight, obesity and metabolic disease. Although there...Full Text Available
Data from 8,032 Manitoba respondents to the 1996/97 Canadian National Population Health Survey were linked to the 1996 census to study whether measures of morbidity, both self-reported and objectively...Full Text Available
BackgroundWebsites of many rogue sellers of medications are accessible through links in email spam messages or via web search engines. This study examined...Full Text Available
Uncoupling protein 2 (UCP2) maps to a region on distal mouse chromosome 7 that has been linked to the phenotypes of obesity and type II diabetes. We recently reported that UCP2 expression is increased...Full Text Available
XMRV or xenotropic murine leukemia virus-related retrovirus, a recently discovered retrovirus, has been linked to both prostate cancer and chronic fatigue syndrome (CFS). Recently, the teams of Drs....Full Text Available
Many epidemiological evidences have proven the association between smoking and periodontal disease. The causality can be further established by linking findings of traditional epidemiological studies...Full Text Available
DNA barcodes linked to genetic features greatly facilitate screening these features in pooled formats using microarray hybridization, and new tools are needed to design large sets of barcodes to allow...Full Text Available
BackgroundPhysical inactivity is related to many morbidities but the evidence of its link with depression in adolescents needs further investigation in view of the existing conflicting...Full Text Available
The worldwide decline in honeybee colonies during the past 50 years has often been linked to the spread of the parasitic mite Varroa destructor and its interaction with certain honeybee...Full Text Available
... exercise to Port Au Prince, Haiti, begins Friday, April 11, 1997, when a company-sized element from the Army's 82nd Airborne Division from Fort ...
BackgroundAcute low back pain is a very common symptom and reason for many medical consultations. In some unusual circumstances it could be linked to a rare aetiology.Case...Full Text Available
In 2000 to 2001, 2003 to 2004, and 2005 to 2006, three outbreaks of Salmonella enterica serovar Enteritidis were linked with the consumption of raw almonds. The S....Full Text Available
and Antibody Responses of Rhesus Macaques Exposed to the Human Gammaretrovirus XMRV external link, opens in new window J Virol. 2011 May;85(9):4547-57 Detection of CWD...
Present investigations suggest that approximately 30% of colorectal cancer (CRC) cases arise on the basis of inherited factors. We hypothesize that the majority of inherited factors are moderately...Full Text Available
... to-noise density than the uplink budget has (74.2 ... in heav:, point-to-point link applications with ... 11.7 Expanded bands allocated (Ku band) (500 MHz ...
... Question Chronic fatigue: Can natural remedies boost my energy? Are there any natural remedies that reduce chronic ... AN01764 ">Chronic fatigue: Can natural remedies boost my energy? Guidelines for sites linking to MayoClinic.com ...
A high-throughput assay for enzyme activity has been developed that is reaction independent. In this assay, a small-molecule yeast three-hybrid system is used to link enzyme catalysis to transcription...Full Text Available
Species differences in lifespan have been attributed to cellular survival during various stressors, designated here as ‘cell resilience’. In primary fibroblast cultures, cell...Full Text Available
Type 2 diabetes mellitus (DM2) is increasing in incidence, creating worldwide public health concerns and impacting morbidity and mortality rates. An increasing number of studies have demonstrated shared...Full Text Available
Initial results obtained with a Monte Carlo computer program designed to link initial physical events in irradiated liquid water with subsequent chemical and biological events are presented. 10 refs., 4 figs., 3 tabs.
Body size variation across the Metazoa is immense, encompassing 17 orders of magnitude in biovolume. Factors driving this extreme diversification in size and the consequences of size variation for biological...Full Text Available
BackgroundHigh intake of sugar-sweetened beverages in childhood is linked to increased risk of obesity and type II diabetes later in life. Using three nationally representative surveys...Full Text Available
... Author: Vets With A Mission Subjects: vietnam, vietnam war, warfare DeweyClass: 959.7043 Resource ... Subjects: vietnam, vietnam war DeweyClass: 959.7 Resource type: bibliography, index World Travel ...
...6 Resource type: documents MmIT: Multimedia Information and Technology Group Group aiming to facilitate communication between CILIP members interested in multimedia developments in the library and information science field. Visits to places of interest like museums and archives are frequently organised, and an email discussion list ...
There is increasing evidence of a biochemical link between lipid oxidation and bone metabolism. Paraoxonase 1 (PON1) prevents the oxidation of low-density lipoprotein (LDL) and metabolizes biologically...Full Text Available
BackgroundThe aim of this paper is to discuss the controversial origins of petals from tepals or stamens and the links between the morphological expression of petals and floral organ...Full Text Available
...research strategy and plans Aquatic resource monitoring research programs, EMAP and STAR grants Go To EMAP homepage Go To Top Bibliography References for survey designs, statistical analyses , program documentation, and monitoring reports. Reports, abstracts and links to electronic versions Go To Top Frequently Asked Questions ...
Antibody avidity to hen egg white lysozyme (HEWL) was measured by thiocyanate ion elution enzyme-linked immunosorbent assay (ELISA) in swine lymphocyte antigen (SLA) defined miniature pigs. Serum antibody...Full Text Available
Human IgG specific for beta-endorphin was identified by enzyme-linked immunoabsorbent assay and isolated by affinity chromatography. From a sample of 27 subjects, three individuals with major depression...Full Text Available
The current study examined the reinforcing effects of choosing among alternatives in a four-part evaluation. In the first study, initial-link responses in a concurrent-chains arrangement resulted in...Full Text Available
Monoclonal antibodies were produced against gamma-irradiated amastigotes of Leishmania major. Five antibodies (T16 through T20) were selected which reacted in enzyme-linked immunoassays with the intracellular...Full Text Available
Acquired resistance to the action of insulin to stimulate glucose transport in skeletal muscle is associated with obesity and promotes the development of type 2 diabetes. In skeletal muscle,...Full Text Available
Adipocyte death has been reported in both obese humans and rodents. However, its role in metabolic disorders, including insulin resistance, hepatic steatosis, and inflammation associated with obesity...Full Text Available
A cDNA encoding a cytochrome P450 enzyme was isolated from a cDNA library of the corpora allata (CA) from reproductively active Diploptera punctata cockroaches. This P450 from the endocrine...Full Text Available
Most hospitals today are quickly developing special programs and services that are designed to compete for physicians and patients, and ultimately fill unoccupied beds. In an attempt to attract physicians...Full Text Available
There is increasing concern for the potential adverse health effects of human exposures to chemical mixtures. To better understand the complex interactions of chemicals within a mixture, it is essential...Full Text Available
We have studied the impact of overexpression of an intracellular signaling protein, integrin-linked kinase (ILK), on the survival and function of encapsulated islet tissue used for the treatment of type 1 diabetes. The dimensions of the encapsulated tissue can impact the stresses placed on the tissue and ILK overexpression shows the ability to extend function of dissociated cells as well as intact islets. These results suggest that lost cell-extracellular matrix interactions in cell encapsulation systems can lead to decreased insulin secretion and ILK signaling is a target to overcome this phenomenon. (communication)
Several enzymes of the metabolic pathways responsible for metabolism of cytosolic ribonucleotides and deoxyribonucleotides are located in mitochondria. Studies described in this paper suggest dysfunction of the mitochondria to affect these metabolic pathways and limit the available levels of cytosolic ribonucleotides and deoxyribonucleotides, which in turn can result in aberrant RNA and DNA synthesis. Mitochondrial dysfunction has been linked to genomic instability, and it is possible that the limiting effect of mitochondrial dysfunction on the levels of nucleotides and resulting aberrant RNA and DNA synthesis in part can be responsible for this link. This paper summarizes the parts of the metabolic pathways responsible for nucleotide metabolism that can be affected by mitochondrial dysfunction.
Noncommutative tori are among historically the oldest and by now the most developed examples of noncommutative spaces. Noncommutative Yang-Mills theory can be obtained from string theory. This connection led to a cross-fertilization of research in physics and mathematics on Yang-Mills theory on noncommutative tori. One important result stemming from that work is the link between T-duality in string theory and Morita equivalence of associative algebras. In this article we give an overview of the basic results in differential geometry of noncommutative tori. Yang-Mills theory on noncommutative tori, the duality induced by Morita equivalence and its link with the T-duality are discussed. Noncommutative Nahm transform for instantons is introduced.
In this study we consider relations between companies in Poland taking into account common branches they belong to. It is clear that companies belonging to the same branch compete for similar customers, so the market induces correlations between them. On the other hand two branches can be related by companies acting in both of them. To remove weak, accidental links we shall use a concept of threshold filtering for weighted networks where a link weight corresponds to a number of existing connections (common companies or branches) between a pair of nodes.
...com: Christianity: General All-in-One Biblical Resources Search Anno Domini: Jesus Through the Centuries Bible and Homosexuality Bible Reading Fellowship Bible Society Bible ...of the New Testament Vine's Expository Dictionary of New Testament Words Virtual Christianity: Bibles Whole Bible Comments: bubl@bubl.ac.uk About....com: Christianity: General Offers original articles and features about Christianity in general plus annotated links to selected relevant Internet resources, compiled by ... Also includes a gallery of Christian images such as The Last Supper by Leonardo Da Vinci. Author: About....
A wrench is proposed for screwing and unscrewing lock connections, which includes a spring loaded base, a faceplate with low moment and high moment mechanisms and subassemblies for moving them. In order to increase the operational reliability, the wrench is equipped with uprights evenly disposed along the perimeter of the base with hinged suspensions for linking the base, the hinged suspension is made in the form of interconnected links for the upper and lower traverses with the hinges. One of the hinges is positioned between the upper traverse and the upright, while the other is located between the lower traverse and the base.
The purpose of the invention is to reduce the labor intensity of assembly and disassembly of a drilling rig with a large unit transport method. To achieve the cited goal, in the base of the drilling rig unit, which contains uprights with hinges, installed between the frame and the foundation support, where each of the hinges is linked by a flexible element with the frame, the frame and the foundation support are equipped with encircling elements installed with the capability of interacting with the flexible element, where the uprights are linked with the frame by means of hinges with the capability of locking and the uprights by means of the encircling and flexible elements are connected in pairs.
The United States Air Force School of Aerospace Medicine (USAFSAM) tests the quantitative fit of masks which are worn by military personnel during nuclear, biological, and chemical warfare. Subjects are placed in a Dynatech-Frontier Fit Testing Chamber, salt air is fed into the chamber, and samples of air are drawn from the mask and the chamber. The ratio of salt air outside the mask to salt air inside the mask is called the quantitative fit factor. A motion-time study was conducted to evaluate the efficiency of the layout and work method presently used in the laboratory. A link analysis was done to determine equipment priorities, and the link data and design guidelines were used to develop three proposed laboratory designs. The proposals were evaluated by projecting the time and motion efficiency, and the energy expended working in each design. Also evaluated were the lengths of the equipment links for each proposal, and ...
Because of the stochastic nature of traffic requirement matrix, it is very difficult to get the optimal traffic distribution to minimize the delay even with adaptive routing protocol in a fixed connection network where capacity already defined for each link. Hence there is a requirement to define such a method, which could generate the optimal solution very quickly and efficiently. This paper presenting a new concept to provide the adaptive optimal traffic distribution for dynamic condition of traffic matrix using nature based intelligence methods. With the defined load and fixed capacity of links, average delay for packet has minimized with various variations of evolutionary programming and particle swarm optimization. Comparative study has given over their performance in terms of converging speed. Universal approximation capability, the key feature of feed forward neural network has applied to predict the flow distribution on each ...
Production in economy is a set of firms' activities as suppliers and customers; a firm buys goods from other firms, puts added-values and sells products to others in a giant network of production. Empirical study has been lacking despite of the fact that the structure of production network is important to understand and make models for many aspects of dynamics in economy. We study a nation-wide production network comprising a million of firms and millions of supplier-customer links by using recent statistical methods developed in physics. We show in the empirical analysis scale-free degree distribution, disassortativity, correlation of degree to firm-size, and community structure having sectoral and regional modules. Since suppliers usually provide credit to their customers, who supply to theirs in turn, each link is actually a creditor-debtor relation. We also study chains of failures or bankruptcies that take place along those ...
In this paper, we propose an antenna selection method in a wireless cognitive radio (CR) system, namely difference selection, whereby a single transmit antenna is selected at the secondary transmitter out of $M$ possible antennas such that the weighted difference between the channel gains of the data link and the interference link is maximized. We analyze mutual information and outage probability of the secondary transmission in a CR system with difference antenna selection, and propose a method of optimizing these performance metrics of the secondary data link subject to practical constraints on the peak secondary transmit power and the average interference power as seen by the primary receiver. The optimization is performed over two parameters: the peak secondary transmit power and the difference selection weight $\\delta\\in [0, 1]$. We show that, difference selection using the optimized parameters determined by the ...
Current regulations guiding technical aspects of natural resource damage assessments combine source, exposure pathway, resource injury, and monetary damage components. In order to associate any observed injury to the uncontrolled release of chemicals (e.g. oil spills, contaminated sediments, in-place toxics, etc.), it is important to link the chemical ''release'' to the injured resource. In complex environmental settings where multiple sources of similar chemicals are combined, multicomponent chemical methods must be used to link the release to the environmental distribution of chemicals. Three examples of the utility of multicomponent organic chemical analyses linked to comprehensive and representative sampling strategies will be discussed--the Shell Martinez Refinery oil spill, the Exxon Valdez oil spill, and a contaminated sediment assessment. These NRDA-based source identifications are based on use of polycyclic ...
ObjectivesProject VOLCANOSCOPE will evaluate strategies (1) for applying existing and new forecasting models to volcanic eruptions, and (2) for identifying methods to improve how forecasts are communicated effectively to vulnerable communities. To link forecasting and communication, the interdisciplinary study will assess how to engage all stakeholders - from monitoring scientists, through emergency agencies, to vulnerable communities - to optimize the understanding of forecasts among different end users. [continued...]DescriptionProject VOLCANOSCOPE will evaluate strategies (1) for applying existing and new forecasting models to volcanic eruptions, and (2) for identifying methods to improve how forecasts are communicated effectively to vulnerable communities. To link forecasting and communication, the interdisciplinary study will assess how to engage all stakeholders - from monitoring scientists, through emergency agencies, to vulnerable ...
Abstract We analyse extinction maps of nearby giant molecular clouds to forge a link between driving processes of turbulence and modes of star formation. Our investigation focuses on cloud structure in the column density range above the self-shielding threshold of 1-mag AV and below the star formation threshold - the regime in which turbulence is expected to dominate. We identify clouds with shallow mass distributions as cluster forming. Clouds that form stars in a less clustered or isolated mode show a steeper mass distribution. Structure functions prove inadequate to distinguish between clouds of different star formation mode. They may, however, suggest that the turbulence in the average cloud is governed by solenoidal forcing. The same is found using the -variance analysis which also in...
Polyurethane (PU) foam was combined with protein drug-loaded pH-sensitive alginate-bentonite hydrogel for wound dressings. Alginate is a linear copolymer composed of 1?4-linked ?-D-mannuronic acid (M) and its c-5-epimer ?-Lguluronic acid (G). The amount of (M) and (G) and their sequential distribution are varied depending on the alginate source. Soluble sodium alginate can become a hydrogel when cross-linked with divalent cations and has widespread applications in the food, drink, pharmaceutical and bioengineering industries. Recently, it has been also proposed as a biomaterial for drug delivery systems. Bentonites are the natural inorganic polymers consisting of a large proportion of expandable clay minerals with a three-layer structure such as montmorillonite, beidellite, nontronite, etc...
A novel method of simultaneous realization of optical carrier-suppression and single-sideband modulation using fiber Fabry-Perot tunable filter is presented. In order to enhance transmission performance of radio over fiber links, we use a fiber Fabry-Perot tunable filter to filter out one sideband as well as suppress the optical carrier power. The results demonstrate 20.5dB and 14.2dB improvement in the signal noise ratios when 18GHz and 10GHz microwave signals carrying 5Mbit/s quadrature-phase-shift-keyed (QPSK) format data is transmitted over 35 km single mode fiber, respectively.
The objectives of this study were to estimate symbiotic nitrogen fixation by two common pasture legumes, Trifolium subterraneum L. and Medicago truncatula Gaertn., and an Australian native legume, Acacia dealbata Link, growing in pots using an indirect isotopic method. This method was also used to calibrate the C2H2 reduction assay of the intact plants. In addition, hydrogen evolution was measured in an attempt to explain the variations in C2H2:N2 ratios between the species. 25 refs.; 1 figure; 4 tabs.
This article argues the importance of ensuring initiatives aimed at improving children-s social and emotional well-being are based on sound participatory principles. The discussion posits links between the recognition of children, dialogic approaches to participation, changing conceptualisations of children and childhood, and children-s well-being. It explores these links in light of one particular initiative, Seasons for Growth (Graham, 1996, 2002, Seasons for Growth; Loss and Grief Education Program. MacKillop Foundation), an education programme built around emerging evidence that giving children a voice assists them to adapt to family change. The paper concludes with insights into what is involved when we locate notions of -having a say- as a key element in promoting children-s well-bei...
...References | Radiation Protection | US EPA This page provides links to the reference material on EPA's Radiation Protection Web site. U.S. EPA/...OAR/ORIA/Radiation Protection Division Jump to main content. Radiation Protection Contact Us Search: All EPA This Area You are here: EPA Home ... Radiation Protection References PageName Technical Users General Public Reporters Librarians Students/Teachers PROGRAMS TOPICS REFERENCES References The Reference Section provides general material that support the ...other sections of EPA's Radiation Protection Web site. You will find links within the information to related pages throughout the Radiation Protection , EPA ...
Chitosan (Ch) microspheres have been developed by precipitation method, cross-linked with glutaraldehyde and used as a template for layer-by-layer (LBL) deposition of two natural polyelectrolytes. Using a LBL methodology, Ch microspheres were alternately coated with hyaluronic acid (HA) and Ch under mild conditions. The roughness of the Ch-based crosslinked microspheres was characterized by atomic force microscopy (AFM). Morphological characterization was performed by environmental scanning electron microscopy (ESEM), scanning electron microscopy (SEM) and stereolight microscopy. The swelling behaviour of the microspheres demonstrated that the ones with more bilayers presented the highest water uptake and the uncoated cross-linked Ch microspheres showed the lowest uptake capability. Micros...
This paper employs a new approach in order to investigate the underlying relationship between stock markets and exchange rates. Current approaches suggest that the relative equity market performance of two countries is linked to their exchange rate. In contrast, this study proposes an alternative approach where one global variable - global equity market returns - is believed to have an effect on exchange rates, with the relative interest rate level of a currency determining the sign of the relationship. Our empirical findings suggest that exchange rates and global stock market returns are strongly linked. The value of currencies with higher interest rates is positively related with global equity returns, whereas the value of currencies with lower interest rates is negatively related with g...
In this paper we describe a modelling project to improve a nuclear waste management program in charge of the creation of a new system for the permanent disposal of nuclear waste. SADT (Structural Analysis and Design Technique) is used in order to provide a work-flow description of the functions to be performed by the waste management program. This description is then translated into a number of Coloured Petri Nets (CPN or CP-nets) corresponding to different program functions where additional behavioural inscriptions provide basis for simulation. Each of these CP-nets is simulated to produce timed event charts that are useful for understanding the behaviour of the program functions under different scenarios. Then all the CPN models are linked together to form a single stand-alone application that is useful for validating the interaction and cooperation between the different program functions. A technique for linking executable CPN models is ...
ABB High Voltage Cables AB started the MPS (More Power Submarine cables) project in 1993 with a view to exploring new technology opportunities. The goal is to design and type test a submarine HVDC cable for a capacity of 1200 MW at 600 kV. On the day before ABB announced its success in winning the contract for the world`s largest ever submarine HVDC link project for the gigantic Bakun project in Malaysia, ABB Power Systems described progress to date at a symposium in Karlskrona. The proceedings included a test demonstration on an extruded cable which eventually broke down at a stress of over 935 kV -not in the insulation itself but in the end terminations. The electric field was in excess of 200 kV/mm which is higher than ever before reported. (UK)
Genetic mapping is approached using the techniques of high resolution fluorescence in situ hybridization (FISH). This technology and the results of its application are designed to rapidly generate whole genome as tool box of expressed sequence to speed the identification of human disease genes. The results of this study are intended to dovetail with and to link the results of existing technologies for creating backbone YAC and genetic maps. In the first eight months, this approach generated 60--80% of the expressed sequence map, the remainder expected to be derived through more long-term, labor-intensive, regional chromosomal gene searches or sequencing. The laboratory has made significant progress in the set-up phase, in mapping fetal and adult brain and other cDNAs, in testing a model system for directly linking genetic and physical maps using FISH with small fragments, in setting up a database, and in establishing the validity and throughput ...
The Dowex 50W-X8 and 50W-Xl2 resin samples are both strong acid cation materials in the hydrogen form. Each material has a water retention capacity characteristic of its respective marketed degree of cross-linking. Dowex 21K gives confirmatory responses to tests for a strong anion exchange resin in the nitrate form. All three resins have the manufacturer's specified ionic type and form, and the Dowex 50W resins have characteristic water retention capacities. These tests conclude that the ion exchange resins in use in FB-Line meet the approved safety document criteria for cross-linking, ionic form, and resin type.
The Dowex 50W-X8 and 50W-Xl2 resin samples are both strong acid cation materials in the hydrogen form. Each material has a water retention capacity characteristic of its respective marketed degree of cross-linking. Dowex 21K gives confirmatory responses to tests for a strong anion exchange resin in the nitrate form. All three resins have the manufacturer`s specified ionic type and form, and the Dowex 50W resins have characteristic water retention capacities. These tests conclude that the ion exchange resins in use in FB-Line meet the approved safety document criteria for cross-linking, ionic form, and resin type.
The stock market has been known to form homogeneous stock groups with a higher correlation among different stocks according to common economic factors that influence individual stocks. We investigate the role of common economic factors in the market in the formation of stock networks, using the arbitrage pricing model reflecting essential properties of common economic factors. We find that the degree of consistency between real and model stock networks increases as additional common economic factors are incorporated into our model. Furthermore, we find that individual stocks with a large number of links to other stocks in a network are more highly correlated with common economic factors than those with a small number of links. This suggests that common economic factors in the stock market can be understood in terms of deterministic factors.
SNAP25 occurs on chromosome 20p12.2, which has been linked to schizophrenia in some samples, and recently linked to latent classes of psychotic illness in our sample. SNAP25 is crucial to synaptic functioning, may be involved in axonal growth and dendritic sprouting, and its expression may be decreased in schizophrenia. We genotyped 18 haplotype-tagging SNPs in SNAP25 in a sample of 270 Irish high-density families. Single marker and haplotype analyses were performed in FBAT and PDT. We adjusted for multiple testing by computing q values. Association was followed up in an independent sample of 657 cases and 411 controls. We tested for allelic effects on the clinical phenotype by using the method of sequential addition and 5 factor-derived scores of the OPCRIT. Nine of 18 SNPs had P values <...
Recent developments in cross-linked polyethylene cables mean they can be used at higher voltages and are starting to replace some oil-filled cables. Their good thermal and electrical properties, easy installation and minimal maintenance have helped their growth. A group at Sumitomo Electric Industries Ltd., Japan is studying the performance of these cables. (author).
This site focuses on the subject of volcanoes, including how volcanoes form, the destruction they can cause, effects of volcanoes on the environment, where active volcanoes are found, volcanoes of other planets, and the different volcano types. Designed as an electronic tour, it guides the user through different web sites and outlines teaching objectives, concepts covered, and new vocabulary. There is a teacher resources section with links for more information, and questions for students to answer along the way.
We present a general procedure to construct the first law of thermodynamics on the apparent horizon and illustrate its validity by examining it in some extended gravity theories. Applying this procedure, we can describe the thermodynamics on the apparent horizon in Randall-Sundrum braneworld imbedded in a nontrivial bulk. We discuss the mass-like function which was used to link Friedmann equation to the first law of thermodynamics and obtain its special case which gives the generalized Misner-Sharp mass in Lovelock gravity.
Cell-free extracts of Acremonium chrysogenum and Streptomyces clavuligerus oxidize the 3-methyl group of desacetoxycephalosporin C to a 3-hydroxymethyl group. The enzyme responsible for this reaction...Full Text Available
β2-microglobulin (β2m) amyloid deposits are linked to dialysis related amyloidosis (DRA) in hemodialysis patients. The mechanism by which β2m...Full Text Available
The author gives an account of tests with the X-phone system. The aim of the tests was to establish the reliability and behaviour of the apparatus mounted on a winning machine and to investigate the possibility of setting up a radio link, without laying an extra wire, between the foot of the tubbing-lined roadway and the winning machine on a steep face. The author describes the face and the test conditions and presents details of the satisfactory test results.
The author examines the place of tachyons and magnetic monopoles in the 'projective relativity' theory, which is based on the De Sitter universe and which has special relativity as a limiting case. A link with a generalized form of Maxwell's equations is examined in detail, the connection being through the rotation group R_5. (W.D.L.).
Abstract Overall Numbers Small, But Study Finds SSRI Exposure, Autism Link Additional Drug Safety, Efficacy Data Needed for Pediatric Bipolar Disorder SGA Safety and Efficacy in Children and Adolescents Aripiprazole Safety and Tolerability for Irritability in Autism No Lisdexamfetamine Effect on Sleep Disturbances in Children With ADHD Sickle Cell Disease With Comorbid Depression Homeopathy in Psychiatry Manic Symptoms Induced by Marijuana in a Healthy Adolescent New Warnings Safety Labeling Changes
MMP, a linear alpha 1 leads to 4 linked polymer of 3-O-methylmannose, regulates the fatty acid synthetase from Mycobacterium smegmatis by forming stoichiometric complexes with the long-chain acyl-CoA...Full Text Available
Oct 24, 1995 ... The photos were made with a Nikon FE and a Sigma 400mm APO f/5.6 lens ... Note: The JPEG images to which the above links point contain subtle ... India on 1995 October 24 with a digital camera and Fe X 6374 ? filter, ...
A slurry intake device is proposed which contains an inlet sleeve, housing with grating installed with the discharge end in the zone of the slurry outlet, and hinged deflector. In order to conserve the clay mud, it is equipped with a tie rod and two-arm lever which is kinematically linked to the deflector and the grating. It is installed by hinges in relation to the housing and the latter is attached by hinges to the inlet sleeve. The deflector is arranged in the zone of slurry outlet. The device is distinguished by the fact that the deflector is equipped with a cantilever on which a fixable weight is attached.
Non-alcoholic fatty liver disease is a serious health problem linked to obesity and type 2 diabetes. To investigate the biological outcome and therapeutic potential of hepatic fatty acid uptake inhibition,...Full Text Available
Background/AimsFabry disease is an X-linked recessive and progressive disease caused by α-galactosidase A (α-GaL A) deficiency. We sought to assess the prevalence...Full Text Available
The ?new variant famine? hypothesis posits links between HIV/AIDS and new patterns of impoverishment, food insecurity and hunger, in southern and eastern Africa. This paper explores the relevance of the NVF hypothesis to understanding Swaziland?s recurrent food crises and high HIV prevalence. Evidence exists that all four markers of NVF are present in Swaziland. The national government and the international community will have to contend with this phenomenon in future planning for the wellbeing of Swazi citizens.
... Wanting to help a charity is commendable but the main focus of generosity should be the people in front of you, not your choice of spiritual overlord - especially so if the group is being funded with money from taxpayers. Recommend? (44) Report abuse | Link ...
Infiltration of radon from the ground is usually the primary source of indoor radon pollution. A uniform method for radon risk classification of foundation soils based on soil-gas radon concentration measurements and on the determination of soil porosity, permeability and structure was proposed in 1990. Results of assessment of some areas in Czechoslovakia, containing more than 5000 radon concentration measurements, demonstrate the utility of the technique and confirm the link between geology and radon potential of the soil. (author)
Modern particle accelerators offer new opportunities to dramatically reshape the way we think about nuclear energy, and challenge some of the thorniest problems linked to its industrial use, e.g. nuclear waste. A powerful proton accelerator driving a sub-critical fission reactor could be used for producing energy more safely and burning up the extra spent fuel which so far has been stored in geological repositories.
The influence of additionally injected short-wavelength photobleaching light on the radiation hardness of Ge-doped graded index fibers working at 1,300 nm wavelength is investigated. Predictions are complicated by the fact that more efficient shortwave bleaching light experiences higher radiation-induced loss. Promising results are found for low fiber temperatures (approx-lt -50 C) and bleaching light of about 835 nm wavelength.
Biofilm-specific antibiotic resistance is influenced by multiple factors. We demonstrated that Pseudomonas aeruginosa tssC1, a gene implicated in type VI secretion (T6S), is important for resistance of biofilms to a subset of antibiotics. We showed that tssC1 expression is induced in biofilms and confirmed that tssC1 is required for T6S. PMID:21784934
... Reduce partner costs, save time, and overcome delays in data transmission. Data Exchanges States are currently submitting data to each other and to the EPA in the exchanges listed below. Data Exchanges are typically referred to by their acronyms, which are listed below. To find out more about EPA data exchanges, please follow the links to EPA Web sites. AQS - Air Quality Sub-system (...
Epidemics are frequently simulated on redundantly wired contact networks, which have many more links between sites than are minimally required to connect all. Consequently, the modelled pathogen can...Full Text Available
The synthesis of a new kind of magnetic, fluorescent multifunctional nanoparticles (~30 nm in diameter) was demonstrated, where multiple fluorescent CdTe quantum dots (QDs) are covalently linked...Full Text Available
The suggestion has been made that stars with collapsing iron cores may be unable to explode, and hence may generate black holes. The situation when the collapsing core is rotating and magnetized is investigated and it is tentatively concluded that these effects make the situation even more conducive to the formation of black holes. (auth)
This study examined the life histories of a group of emerging scholars in the field of mathematics education who identify themselves as having a particular interest in and concern for issues of equity and diversity. Experiences of being the "other," "bearing witness" to "othering experiences," and "orienting experiences" in relation to issues of equity proved to be prominent themes in participants' life histories. These experiences were then linked to the positionality that these scholars now have in relation to their research in mathematics education.
DescriptionThe overall objective of the project is to provide an improved understanding of the processes and linkages through which organic carbon additions influence soil bio-physical and physico-chemical properties. Soil organic carbon (SOC) levels and turnover rates are intimately linked to the soil properties that are important in the maintenance of soil quality and fertility, and sustainable crop production. However, it has been difficult to distinguish the various processes and linkages through which [continued...
DescriptionThe switch from production-linked to environmental payments has focussed attention on the environmental impacts of farming. There is a growing awareness of the need to reduce the contamination of air with carbon dioxide, methane, ammonia and nitrogen gases (which contribute to the greenhouse effect) and to prevent the contamination of soil and water with excessive amounts of nitrogen, phosphorus and potassium. As beef production moves to become more sustainable and fully integrated with the wide [continued...
An optical voltage reference for providing an alternative to a battery source. The optical reference apparatus provides a temperature stable, high precision, isolated voltage reference through the use of optical isolation techniques to eliminate current and impedance coupling errors. Pulse rate frequency modulation is employed to eliminate errors in the optical transmission link while phase-lock feedback is employed to stabilize the frequency to voltage transfer function.
...of Mixing Sections 9 Interacting Rotor/Stator Mixers 10 Floating Ring Mixing Devices 11 Static (or Motionless) Mixers 12 Incorporation of Liquid Additives and Dispersions by Direct Addition 13 Dispersive Mixing of Fillers and Pigments 14 Dispersive Mixing Applied to Polymer Blending 15 Compounding with Single Screw Extruders Appendix - Preparation of Microtome Sections for Assessment of Dispersive In order to get a feel for this book, you can view Chapter 1 now, simply follow the link ...
... Piled foundations were adopted and precast concrete piles 6 - 8 m long were driven through the alluvial soils onto a solid bed rock. Special precautions were taken to ensure vibrations did not affect an adjacent apartment block. 88 piles were driven in 2 working days. Navigation - Home - Services - Previous projects - Contact Us - Philosophy - About us - Water Slides - Links ...
...Assemblages of plants and invertebrate animals of tumulus (organic mound) springs of the Swan Coastal Plain Assemblages of plants and invertebrate animals of tumulus ...organic mound) springs of the Swan Coastal Plain [Skip navigation links] About us | Contact us | Publications |...ecological communities Assemblages of plants and invertebrate animals of tumulus (organic mound) springs of the Swan Coastal Plain Advice to the Minister for the ...of the 'Assemblages of plants and invertebrate animals of tumulus (organic mound) springs of the Swan Coastal Plain' community sufficient to distinguish it from ...
This project is designed to establish one basis for empirically linking aspects of management and organizational design to the safe operation of nuclear power plants. Current work is focusing on (a) reviewing existing literature relevant to this linkage, and (b) isolating and incorporating numerous safety relevant indicators. Later stages of this project will involve hypothesis development, data collection and analysis.
Enzyme-linked immunosorbent assays for the detection of immunoglobulin M (IgM), IgA, IgG1, and IgG2 antibodies against bovine respiratory syncytial virus (BRSV) were used to measure antibody responses...Full Text Available
Mission-directed public-sector research facilities are experiencing increasingly severe budget environments while seeing expanding missions and responsibilities. In an effort to identify research leveraging methodologies an information search was conducted in conjunction with some efforts to find the proper links to systems engineering fundamentals. The result is an initial model for use in a pre-concept/phase-1 engineering design organization, with a goal of improving the organizations performance.
The leukocyte-enriched p110γ and p110δ isoforms of PI3K have been shown to control in vitro degranulation of mast cells induced by cross-linking...Full Text Available
Interpenetrated lattices (IPL) are combinations of reticulated polymers linked together by permanent crisscross. This structure is well-adapted to combined highly incompatible pairs of polymers. The in-situ sequential method has been applied successfully to the synthesis of ethylene poly-oxides / poly-siloxanes IPLs. The results concerning the preparation of such lattices and their behaviour as solid polymer electrolytes are presented in this paper. (J.S.) 24 refs.
AbstractThe gag p6 region of HIV-1 has various nonsubstitutionary mutations, including insertions, duplications, deletions, and premature stop codons. Studies have linked gag p6 mutations...Full Text Available
These documents defines the interconnection France-England rules for the 2000 MW DC submarine cable directly linking the transmission networks of England and Wales and France. Rights to use Interconnector capacity from 1 April 2001 are to be offered through competitive tenders and auctions, full details of which are set out in the Rules. The contract and a guide to the application form are provided. (A.L.B.)
The loosening equipment consists of a base machine and four-link suspension mechanism which is a cross frame with loosening gear connected to the base machine by universal hinges. In order to improve the reliability of the machine, the drive of transverse shifting in the cross frame is made of symmetrically arranged, shock-absorbing, hydraulic cylinders which are connected by additional universal hinges to the base machine and the lower pull rods. The design of the loosening machine guarantees its reliable operation on soil with significant quantity of hard inclusions.
With the frequent load changes to which a hard coal power station is subjected in the middle and peak load range, great demands are linked with the transient behaviour of the steam generator. Due to the serial connection of the crusher and boiler, the strongly delaying transient behaviour of the crusher compounds entirely with the transient behaviour of the steam generator. Therefore, a suggestion is to be made here as to the improvement of the dynamics of the crusher.
This document, the Standards/Requirements Identification Document (S/RID) Phase I Assessment Report for the subject facility, represents the results of an Administrative Assessment to determine whether S/RID requirements are fully addressed by existing policies, plans or procedures. It contains; compliance status, remedial actions, and an implementing manuals report linking S/RID elements to requirement source to implementing manual and section.
After presenting three ways of defining a bulge component in disc galaxies, we introduce the various types of bulges, namely the classical bulges, the boxy/peanut bulges and the disc-like bulges. We then discuss three specific topics linked to bulge formation and evolution, namely the coupled time evolution of the bar, buckling and peanut strengths; the effect of velocity anisotropy on peanut formation; and bulge formation via bar destruction.
...org/ (1 vote) defends the native forest ecosystems and communities of the Southeast United States which are threatened by industrial scale clearcutting to feed chip mills Added: Jan. 20, 2001 | Rate It Don't Buy SFI http://www.dontbuysfi.com/home/ (2 votes) campaign to show the \\
APP is a transmembrane precursor of beta-amyloid. In dominantly inherited familial Alzheimer's disease (FAD), point mutations V6421, V642F and V642G have been discovered in APP695. Here we show that...Full Text Available
The theory of reliability is used to develop statistical field data on malfunctions of units of sucker rod well pumps (UShSN). The indices of reliability of the UShSN are applied for establishment of the cause-effect links between the operating factors. Dependences of operating time on the depth of suspension of the pumps, mode of pumping out, degree of flooding of the oil, and twisting of the shafts are established for conditions of specific fields. The obtained relationships can be used in selecting and optimizing the work of the UShSN.
Occupational and environmental exposure to organic ligands, solvents, fuel hydrocarbons, and polychlorinated biphenyls are linked with increased risk of hematologic malignancies. DOE facilities and waste sites in the U.S. are contaminated with mixtures of potentially hazardous chemicals such as metals, organic ligands, solvents, fuel hydrocarbons, polychlorinated biphenyls and radioactive isotopes. A major goal of this project was to establish linkage between chemical/radiation exposure and induction of genomic damage in target populations with the capability to undergo transformation.
A research report presents the basic data required when designing a building with minimal environmental impacts. Topics covered include the energy consumption of building elements during their lifetime, the environmental implications linked to the extraction and processing of building material and the energy consumed in buildings by the occupants. (UK)
This document deals with energy management in buildings. It presents the conditions for a good implementation of energy management. These conditions include the total involvement of the management and the training of the staff. The structure of this implementation is presented together with the tools for an efficient energy management. Eventually, information on air quality and comfort in buildings is provided, as well as the management of complaints linked to them. (TEC). 1 tab.
Whether the lusitropic potential of short-term exercise in aged rats is linked to an augmentation in the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and an alteration in the...Full Text Available
Explicit analytical formulas are derived for the stress intensity factors at the tips of a main crack and of a microcrack for the two-dimensional case of a collinear microcrack. This configuration is used to derive an estimate of the toughness degradation due to microcracks linking up with an advancing main crack. The implications of this estimate for theoretical predictions of the toughening due to stress-induced microcracking are discussed.
... 01, 2009 | Rate It Marine Technology Society https://www.mtsociety.org/home.aspx emphasizes the importance of marine technology as it applies to global issues, encourages marine technology education and facilitates the use of marine technology in managing marine resources Added: Mar. 11, 2010 |...
X-linked sideroblastic anemia with ataxia (XLSA/A) is a rare inherited disorder characterized by mild anemia and ataxia. XLSA/A is caused by mutations in the ABCB7 gene, which encodes...Full Text Available
The previously described (M. De Kesel, P. Gilot, M.-C. Misonne, M. Coene, and C. Cocito, J. Clin. Microbiol., 31:947-954, 1993) a362 recombinant polypeptide of Mycobacterium paratuberculosis was used...Full Text Available
This project proposes to design and develop a new class of power converters (direct DC to AC) to drastically improve performance and optimize the cost, size, weight and volume of the DC to AC converter in SOFC systems. The proposed topologies employ a high frequency link; direct DC to AC conversion approach. The direct DC to AC conversion approach is more efficient and operates without an intermediate dc-link stage. The absence of the dc-link, results in the elimination of bulky, aluminum electrolytic capacitors, which in turn leads to a reduction in the cost, volume, size and weight of the power electronic converter. The feasibility of two direct DC to AC converter topologies and their suitability to meet SECA objectives will be investigated. Laboratory proto-type converters (3-5kW) will be designed and tested in Phase-1. A detailed design trade-off study along with the test results will be available in the form of a ...
High nitrate contents (up to 200 mgl) has been observed in wells drilled into fractured aquifers lying beneath layers of weathered and decayed rock in the humid tropics where annual rainfall is over 1,000 mm and where there is no notable pollution. The source of the nitrates is linked mainly with localized deforestation by man.
This work shows the influence of the consumer density (density/km) in rural electric networks implementation costs. The analysis of the costs aims the criteria definition for the calculation of the financial involving rates of the rural consumer density. 3 figs., 10 tabs.
Studies of flower development in core eudicot species have established a central role for B class MADS-box genes in specifying petal and stamen identities. Similarly in maize and rice, B class genes...Full Text Available
... For more information regarding computer recycling visit www.recyclenow.com For further information on Recycling click on the links below Aluminium Recycling Charity Recycling Computer Recycling Clothes Recycling Ink Cartridge Recycling Local Recycling Home Composting Glass Recycling Mobile Phone Recycling Oil Recycling Plastic Recycling Recycling Bins ...
To reduce the number of regular break-ins on CERN machines due to passwords exposed on the network in clear text, OFF-SITE FTP ACCESS TO CERN WILL BE BLOCKED in the CERN firewall from: Tuesday 20th January 2004 If you use ftp to access CERN computers from outside CERN then please see the link below for alternative access means and further advice: http://cern.ch/security/ftp Denise Heagerty, CERN Computer Security officer, Computer.Security@cern.ch
To reduce the number of regular break-ins on CERN machines due to passwords exposed on the network in clear text, OFF-SITE FTP ACCESS TO CERN WILL BE BLOCKED in the CERN firewall from: Tuesday 20th January 2004 If you use ftp to access CERN computers from outside CERN then please see the link below for alternative access means and further advice: http://cern.ch/security/ftp Denise Heagerty, CERN Computer Security officer, Computer.Security@cern.ch
The level of indole-3-acetic acid (IAA) was locally modified in cambial tissues of transgenic aspen (Populus tremula L. × Populus tremuloides Michx.). We also...Full Text Available
...com: Directory Enquiries International Dialing Codes International Telephone Directory White and Yellow Pages Europe WhoWhere? Yell: Electronic Yellow Pages Comments: bubl@...6 Resource type: directory International Dialing Codes Table listing country codes (for makes telephone calls to that country) and IDD (International ...Direct Dialing) prefixes (for dialing abroad from that country). Author: Kropla, Steve ...
...Observatory Edinburgh SkyView Virtual Observatory Solar System Simulator Space Telescope Science Institute Space Weather : A Research Perspective Subaru Telescope Project Two Micron All ...Universities for Research in Astronomy Subjects: space observation DeweyClass: 522 Resource type: index Space Weather : A Research Perspective Documents discussing space weather , the ...elements of near-Earth space, Earth-space meteorology and practical consequences of space weather . Glossary included. Author: National Academy of ...
...6 Resource type: reference data Global Change Master Directory An extensive source of information about satellite and in situ Earth science data, with broad coverage of the atmosphere, hydrosphere, oceans, solid earth, and biosphere. Author: NASA Subjects: climatology, global change, oceanographic data DeweyClass: 551.6 Resource type: documents, news International ...
... Author: Radev, Dragomir R. Subjects: natural language processing DeweyClass: 764 Resource type: document Natural Language Processing Research Group Research Group based in the Department of Computer Science, University of Sheffield. Conducts research into natural language analysis topics including data mining/information extraction, dialogue, and semantics. Author: Department of Computer Science, University of Sheffield Subjects: natural language processing DeweyClass: 764 Resource ...
DescriptionRemote sensing of the sea surface from satellites in near-polar orbits has contributed greatly to our understanding of the links between physical and biological processes in marine systems. However most of this progress has been made in open oceanic waters or major upwelling areas, and many unresolved problems are encountered in coastal regions and shelf seas. In these optically complex waters, quantitative remote sensing requires a more sophisticated interpretation strategy than that implemente [continued...
2D simulation modeling of a river basin is based on notion of a River Basin as an opened non equilibrium nature system. All components of the system (elevation, water, soil properties and others) are linked to single multi - functional model. The objective of flood simulation is one the model functions. The objectives of the paper are as follows: a mean scale basin floods computing and the model validation; a large scale basin simulation and demands for its validation; results and demands for flood hazard assessment. (orig.)
The transcriptional co-activator PGC-1α regulates functional plasticity in adipose tissue by linking sympathetic input to the transcriptional program of adaptive thermogenesis. We report here...Full Text Available
MicroRNAs are short (∼22 nucleotides) noncoding RNAs that regulate the stability and translation of mRNA targets. A number of computational algorithms have been developed to help predict which...Full Text Available
4.5S RNA is a group of RNAs 90 to 94 nucleotides long (length polymorphism due to a varying number of UMP residues at the 3' end) that form hydrogen bonds with poly(A)-terminated RNAs isolated from...Full Text Available
nl/guid /item item titleNieuwe rol overheid nodig voor schone economie/title ...nl/nieuws/nieuwsberichten/2011/nieuwe-rol-overheid-nodig-voor-schone-economie/link description<p>De in de maatschappij ...gt; <a href="/nieuws/persberichten/2011/nieuwe-rol-overheid-nodig-voor-schone-economie">Nieuwe rol overheid nodig voor schone
A series of line fault tests have been conducted at completion of Stage I of the Hokkaido-Honshu HVDC Link of Electric Power Development Co., Ltd., prior to its commercial operation, in order to study transient overvoltages and overcurrents and to confirm safety operation of system protecting devices in case of DC transmission line faults. The Hokkaido-Honshu HVDC Link is a metallic return HVDC overhead line and cable transmission system, currently being a monopolar system. For this, measurements were conducted this time on reverse polarity overvoltages occurring on main line cable, return line overvoltages, fault arc dynamic characteristics, and DC bypass current through the AC system. The results obtained were then compared with the analysis results by the HVDC surge similator or digital simulation conducted for system design prior to the field tests. As a result, a close accordance was found between them, in confirmation of the effectiveness ...
Using a unique high-frequency futures dataset, we characterize the response of U.S., German and British stock, bond and foreign exchange markets to real-time U.S. macroeconomic news. We find that news produces conditional mean jumps; hence high-frequency stock, bond and exchange rate dynamics are linked to fundamentals. Equity markets, moreover, react differently to news depending on the stage of the business cycle, which explains the low correlation between stock and bond returns when averaged over the cycle. Hence our results qualify earlier work suggesting that bond markets react most strongly to macroeconomic news; in particular, when conditioning on the state of the economy, the equity and foreign exchange markets appear equally responsive. Finally, we also document important contemporaneous links across all markets and countries, even after controlling for the effects of macroeconomic news.
Preliminary results from a large-scale testbed of advanced lighting control technologies at the Phillip Burton Federal Building at 450 Golden Gate Ave. in San Francisco are presented. The first year objective of this project is to determine the sustainable energy savings and cost-effectiveness of different lighting control technologies compared to a portion of the building where only minimal controls are installed. The paper presents the analyzed results from six months of tests focused on accurately characterizing the energy savings potential of one type of daylight-linked lighting controls compared to the lighting in similar open-planned areas without dimming controls. After analyzing a half year;s data, we determined that the annual energy savings for this type of daylight- linked controls was 41% and 30% for the outer rows of lights on the South and North sides of the building, respectively. The annual energy savings dropped to 22% and 16% ...
Developing markets in the Pacific Basin depend heavily on the production and export of consumer goods. The generation of hazardous waste as a by-product of industrial production can be linked to adverse health outcomes, such as childhood leukemia, in ways that are presently unknown. In California, exposures resulting from hazardous waste disposal are of concern in the etiology of childhood cancer. Approximately 63% of the 57 hazardous waste sites that the U.S. Environmental Protection Agency (USEPA) included in the national priority list under the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) statute were in the six-county San Francisco Bay area. This area includes California`s Silicon Valley, where a disproportionate majority of these sites are located. Although only one study links hazardous waste disposal to childhood leukemia evidence is accumulating that in utero and maternal pesticide exposures as well as ...
Genetic mapping is approached using the techniques of high resolution fluorescence in situ hybridization (FISH). This technology and the results of its application are designed to rapidly generate whole genome as tool box of expressed sequence to speed the identification of human disease genes. The results of this study are intended to dovetail with and to link the results of existing technologies for creating backbone YAC and genetic maps. In the first eight months, this approach generated 60--80% of the expressed sequence map, the remainder expected to be derived through more long-term, labor-intensive, regional chromosomal gene searches or sequencing. The laboratory has made significant progress in the set-up phase, in mapping fetal and adult brain and other cDNAs, in testing a model system for directly linking genetic and physical maps using FISH with small fragments, in setting up a database, and in establishing the validity and throughput ...
The present investigation compares the suitability of two radiolabeling techniques for hemoglobin. "1"2"5I labeling of hemoglobin with Iodogen as iodinating agent caused major changes in the chromatographic behaviour and an accelerated plasma clearance of the labeled hemoglobin in rats. A recently developed two-step procedure for "9"9"mTc labeling gave better results. The label had only minimal influence on the chromatographic behaviour of hemoglobin. In vivo, no free label occurred in the circulation and no transfer of the label to other plasma proteins took place. The plasma clearance of "9"9"mTc-labeled hemoglobin in rats was slowed. However, this could be explained entirely by diminishing glomerular filtration, probably by inhibition of the dissociation of the hemoglobin molecule into dimers. The plasma clearance of hemoglobin modified by intramolecular cross-linking, which prevents dissociation of the molecule into dimers and thus excretion by the kidney, was ...
Anti-proton and positron Galactic cosmic ray (GCR) spectra are among the key targets for indirect detection of dark matter (DM). The boost factors, corresponding to an enhancement of the signal|linked to the clumpiness properties of the dark matter distribution|, have been taken as high as thousands in the past. The dramatic impact of these boost factors for indirect detection of antiparticles, for instance with the PAMELA satellite or the coming AMS-02 experiment, asks for their detailed calculation. We take into account the state-of-the-art results of high resolution N-body dark matter simulations to calculate the most likely energy dependent boost factors|linked to the GCR propagation properties|, for anti-protons and positrons. The results from extreme, but still possible, configurations of the clumpy dark matter component is also discussed. Starting from the mass and space distributions of sub-halos, the anti-proton and positron ...
Horseradish peroxidase (HRP) was chemically modified using cyanuric chloride (CC) as a linking agent onto a carbon felt (CF), which is a microelectrode ensemble of micro carbon fiber (>7mm, diameter) with a random three-dimensional structure. The resulting HRP-modified CF (HRP-ccCF) exhibited well-defined redox waves based on the HRP heme Fe^I^I^I/Fe^I^I redox couple at -0.23V vs. Ag/AgCl (at pH 7.0), while the HRP-adsorbed CF (HRP-CF) showed no apparent redox couple in the same potential range, indicating that the chemical modification of HRP via CC facilitated the direct electron transfer (DET) between HRP and CF. The apparent heterogeneous electron transfer rate constant ks was estimated to be 35s^-^1. Cyclic voltammetry and electrochemical impedance spectroscopy revealed that the inter...
Transmission terminations available today are very reliable, but they need to be. In the field, they are continually exposed to pollution and extremes of ambient temperature. In many cases, they are in the rifle sights of vandals. In contrast, cable joints - often cited as the weakest links from an electrical viewpoint - are generally protected from physical damage underground and many of the short cable systems being installed in the US today can be built without joints. All cable systems need terminations - mostly to air-insulated equipment. At 69 through 138 kV, there is intense competition among manufacturers to supply terminations for solid-dielectric cable that are low in cost, reliable, and require a minimum of skill to install. Some utilities are looking also for terminations that fit a range of cable sizes; terminations that do not contain liquid that can leak out; and terminations that are shatter-proof. All of these improvements are available in the US ...
We consider network coding for networks experiencing worst-case bit-flip errors, and argue that this is a reasonable model for highly dynamic wireless network transmissions. We demonstrate that in this setup prior network error-correcting schemes can be arbitrarily far from achieving the optimal network throughput. We propose a new metric for errors under this model. Using this metric, we prove a new Hamming-type upper bound on the network capacity. We also show a commensurate lower bound based on GV-type codes that can be used for error-correction. The codes used to attain the lower bound are non-coherent (do not require prior knowledge of network topology). The end-to-end nature of our design enables our codes to be overlaid on classical distributed random linear network codes. Further, we free internal nodes from having to implement potentially computationally intensive link-by-link error-correction.
SNAP25 occurs on chromosome 20p12.2, which has been linked to schizophrenia in some samples, and recently linked to latent classes of psychotic illness in our sample. SNAP25 is crucial to synaptic functioning, may be involved in axonal growth and dendritic sprouting, and its expression may be decreased in schizophrenia. We genotyped 18 haplotype-tagging SNPs in SNAP25 in a sample of 270 Irish high-density families. Single marker and haplotype analyses were performed in FBAT and PDT. We adjusted for multiple testing by computing q values. Association was followed up in an independent sample of 657 cases and 411 controls. We tested for allelic effects on the clinical phenotype by using the method of sequential addition and 5 factor-derived scores of the OPCRIT. Nine of 18 SNPs had P values Irish family sample. Although we failed to replicate this in an independent sample, this gene should be further tested in other samples. PMID:19806613
Association rule mining aims to explore large transaction databases for association rules. Classical Association Rule Mining (ARM) model assumes that all items have the same significance without taking their weight into account. It also ignores the difference between the transactions and importance of each and every itemsets. But, the Weighted Association Rule Mining (WARM) does not work on databases with only binary attributes. It makes use of the importance of each itemset and transaction. WARM requires each item to be given weight to reflect their importance to the user. The weights may correspond to special promotions on some products, or the profitability of different items. This research work first focused on a weight assignment based on a directed graph where nodes denote items and links represent association rules. A generalized version of HITS is applied to the graph to rank the items, where all nodes and links are allowed to have ...
Maternal exposure to ambient air pollution has increasingly been linked to adverse pregnancy outcomes. The evidence linking this exposure to congenital anomalies is still limited and controversial. This case-control study investigated the association between maternal exposure to ambient particulate matter with aerodynamic diameter less than 10 ?m (PM(10)), sulfur dioxide (SO(2)), nitrogen dioxide, nitric oxide (NO), ozone (O(3)), and carbon monoxide (CO) and the occurrence of congenital heart disease in the population of Northeast England (1993-2003). Each case and control was assigned weekly average (weeks 3-8 of pregnancy) of pollutant levels measured by the closest monitor to the mother's residential postcode. Using exposure as both continuous and categorical variables, logistic regression models were constructed to quantify the adjusted odds ratios of exposure to air pollutants and the occurrence of each outcome group. We found exposure to ...
Mobile entities with wireless links are able to form a mobile ad-hoc network. Such an infrastructureless network does not have to be administrated. However, self-organizing principles have to be applied to deal with upcoming problems, e.g. information dissemination. These kinds of problems are not easy to tackle, requiring complex algorithms. Moreover, the usefulness of pure ad-hoc networks is arguably limited. Hence, enthusiasm for mobile ad-hoc networks, which could eliminate the need for any fixed infrastructure, has been damped. The goal is to overcome the limitations of pure ad-hoc networks by augmenting them with instant Internet access, e.g. via integration of UMTS respectively GSM links. However, this raises multiple questions at the technical as well as the organizational level. Motivated by characteristics of small-world networks that describe an efficient network even without central or organized design, this paper proposes to ...
This article briefly comments on some stumbling-blocks to climatic change modelling accuracy - in assessments of the greenhouse effect, 25% (missing link) of atmospheric carbon dioxide absorption is still unaccounted for; 1989 World Bank estimates of the Amazon rain forest deforestation rate have since proven to be inaccurate; there are difficulties in assessing the movement of the earth's crust relative to variations in sea level; and different studies vary in results relative to global temperature measurement and trend assessment. The need for an assessment of the economic impacts of increased atmospheric concentrations of carbon dioxide is also pointed out.
The purpose is to describe problems associated with the establishment of vegetation on mined lands and practical rehabilitation and restoration methods for establishing a rehabilitation plan. Land disturbed by mining should be restored to its original state, when the mine is decommissioned, but before that can be attained, site problems such as toxicity, moisture supply, and texture must be rectified. The land may need to pass through several conditioning stages, and links need to be formed to maintain a functioning ecosystem. A key aspect to rehabilitation is the need to increase the organic matter content of the substrate. This improves soil structure, increases the moisture holding ability, and provides a pool for nutrient cycling. 11 refs., 2 tabs.
The purpose is to define sustainable economic development in the context of nonrenewable resources and to examine the changing nature of reclamation over time. Sustainable development is development that ensures the present utilization of resources and the environment does not damage prospects for their use by future generations. Polls show that the public is demanding higher environmental standards. One mechanism for achieving sustainable economic development for the nonrenewable resource sector is through reclamation. The Alberta government`s approach to reclamation is reviewed to show how reclamation and sustainable government are linked together. The history of reclamation legislation in Alberta is summarized. 10 refs.
Several works about annual meeting of the Brazilian Chemical Society are present.The search for medicinal chemistry, natural products, biological chemistry, and organic chemistry are shown. Conventional methods and some techniques are discussed and developments of new methods of determining are studied. The use of new chemical compounds, materials, structures and chemical analysis are shown.
The Data Acquisition System for the CDMS II dark matter experiment was designed and built when the experiment moved to its new underground installation at the Soudan Lab. The combination of remote operation and increased data load necessitated a completely new design. Elements of the original LabView system remained as stand-alone diagnostic programs, but the main data processing moved to a VME-based system with custom electronics for signal conditioning, trigger formation and buffering. The data rate was increased 100-fold and the automated cryogenic system was linked to the data acquisition. A modular server framework with associated user interfaces was implemented in Java to allow control and monitoring of the entire experiment remotely.
As the cost of developing completely new computer codes becomes prohibitive, designers of nuclear facilities are turning to more cost-effective approaches for meeting increasingly strict regulatory requirements applied to safety-related analysis. For designing and licensing the MAPLE family of research reactors, Atomic Energy of Canada Ltd. (AECL) is employing the strategy of adapting major existing codes by linking them together within networks of custom-built interface software. This approach builds on the international investment in developing, maintaining, and verifying existing primary codes and focuses on the less onerous development of interface codes. The resultant code systems are then validated for the new applications of interest.
Research continued on the synthesis of model compounds for coal liquefaction research. This report covers the actual laboratory investigation performed during the reporting period in order to attain the stated objective of the project, viz, the synthesis of a model compound containing tetrahydronaphthalene, naphthalene and phenyl moieties linked by methylene, ethylene and ether bonds. The overall synthetic approach aimed at obtaining the end product has been broken down into three major steps that involve the synthesis of three key reactive intermediates. These are: (1) 3,5-dimethyl-5-bromobenzyl chloride, (2) 1-chloromethylene-2-hydroxytetralin and (3) 2-chloromethylene-1-hydroxynaphthalene.
The energy fed by active galactic nuclei to the surrounding diffuse baryons changes the latter's amount, temperature, and distribution; so in groups and in member galaxies it affects the X-ray luminosity and also the Sunyaev-Zel'dovich effect. Here we compute how the latter is enhanced by the transient blastwave driven by a shining quasar, and is depressed when the equilibrium is recovered with a depleted density. We constrain such depressions and enhancements with the masses of relic black holes in galaxies and the X-ray luminosities in groups. We discuss how all these linked observables can tell the quasar contribution to the thermal history of the baryons pervading galaxies and groups.
Of the radionuclides with physical properties most suited for use with monoclonal antibody for tumor imaging or therapy, few are more available or desirable than Pb-203, 212 and Bi-212. Yet no clinical studies have as yet been possible solely due to the lability in vivo of known complexes. We now report that bismuth complexes of the ligands p-SCN-Bz-DOTA and p-SCN-Bz-trans-cyclohexylDTPA are effective at protecting Bi-206 from release when linked to immunoproteins. Practicable, efficient ligand syntheses will be reported. Initial studies reveal that antibody is labeled efficiently with radiolead DOTA complexes. Preliminary studies indicate stability in vivo.
Recent research work on adjustable speed pumped storage plants conducted in Japan, the USA and Europe suggests that they have many advantages over fixed-speed plants, and can contribute to power system regulation even in pump mode. This paper describes two types of static frequency converter for such pumped storage plants, especially those with greatly fluctuating heads. The design characteristics and operation of the doubly fed induction machine and the synchronous machine with DC link converter are set out and the devices compared. (UK)
We demonstrate the rapid optical characterization of large numbers of individual metal nanoparticles freely diffusing in colloidal solution by confocal laser spectroscopy. We find that hollow gold nanospheres and solid silver nanoparticles linked with a bifunctional ligand, both designed nanostructures, exhibit significantly higher monodispersity in their Rayleigh and Raman scattering response than randomly aggregated gold and silver nanoparticles. We show that measurements of rotational diffusion timescales allow sizing of particles significantly more reliably than can be obtained using translational diffusion timescales.
Three novel inosine-based dinuclear platinum complexes have been synthesized via a solid-phase strategy. In these compounds, the metal is linked both to the N-7 of the purine nucleus and to the terminal amine group of a hexylamine side chain installed on N-1. Cis- or trans- diamine as well as ethylenediamine ligands are coordinated to platinum along with a chloride. The synthesised complexes were tested against four different human tumor cell lines. One of these complexes proved to be more cytotoxic than cisplatin against the MCF7 cancer cell line in a short-term exposure assay.
Summary: SHAP (simple high-throughput annotation pipeline) is a lightweight and scalable sequence annotation pipeline capable of supporting research efforts that generate or utilize large volumes of DNA sequence data. The software provides Grid capable analysis, relational storage and Web-based full-text searching of annotation results. Implemented in Java, SHAP recognizes the limited resources of many smaller research groups. Availability: Source code is freely available under GPLv3 at External Link Not Shown. Contact: matt.demaere@unsw.edu.au; r.cavicchioli@unsw.edu.au
Innate immune responses are regulated by microorganisms and cell death, as well as by a third class of stress signal from the nervous and endocrine systems. The innate immune system also feeds back, through the production of cytokines, to regulate the function of the central nervous system (CNS), and this has effects on behaviour. These signals provide an extrinsic regulatory circuit that links physiological, social and environmental conditions, as perceived by the CNS, with transcriptional 'decision-making' in leukocytes. CNS-mediated regulation of innate immune responses optimizes total organism fitness and provides new opportunities for therapeutic control of chronic infectious, inflammatory and neuropsychiatric diseases.
...named Chair at Epworth Hospital Professor Nilmini Wickramasinghe has been named Chair, Health Information Management , at Epworth HealthCare. Related links School of Business ...the College of Business at RMIT University has been named Epworth Chair, Health Information Management , by Epworth HealthCare. Professor Wickramasinghe has more than ... Professor Wickramasinghersquo;s appointment as Epworth Chair, Health Information Management , will help to further strengthen this clinical academic alliance, with RMIT now ...
This course in System Reliability and Analysis Techniques focuses on the probabilistic quantification of accident sequences and the link between accident sequences and consequences. Other sessions in this series focus on the quantification of system reliability and the development of event trees and fault trees. This course takes the viewpoint that event tree sequences or combinations of system failures and success are available and that Boolean equations for system fault trees have been developed and are available. 93 figs., 11 tabs.
We have prepared a series of novel gemini surfactants having ester bonds in their structures. These surfactants possess two identical hydrophilic polyethylene glycol moieties, two hydrophobic alkyl group moieties, and an anionic spacer. The structures of these compounds were confirmed through infrared and nuclear magnetic resonance spectroscopic and elemental analyses. The novel gemini surfactants exhibit excellent surface activity in terms of their surface tension, low-foaming, wetting power, and fluorescence properties. The presence of the ester linkages made these structures cleavable surfactants.
Several commercially available capacitors were evaluated at the liquid nitrogen temperature (77 K). Our primary interest was their performance under a bias voltage when used as DC link capacitors in cryogenic power electronics. In general, the performance of polymer capacitors and certain ceramic capacitors is almost independent of the temperature, DC bias, and frequency. On the other hand, ceramic capacitors based on high dielectric constant materials showed a strong dependence on the boundary conditions. Aluminum electrolytic capacitors showed a dramatic decrease of capacitance at 77 K, possibly due to the electrolyte being frozen and therefore losing its conductivity.
A method for the determination of different ''bare'' characteristics of the one-particle motion and one-particle basis in magic nuclei is described. The method is based on separating out the mixing with phonons from the phenomenological one-particle characteristics. By means of a generalization of the procedure for localization of the mass operator, relations linking the bare and phenomenological characteristics are obtained. The radial dependence of these characteristics in finite nuclei and the influence of the quasiparticle--phonon interaction on the phenomenological characteristics are studied. Calculations are performed for the neutrons in /sup 208/Pb.
Recent research developments in common-pool resource models emphasize the importance of links with ecological systems and the presence of non-linearities, thresholds and multiple steady states. In a recent paper Kossioris et al. (2008) develop a methodology for deriving feedback Nash equilibria for non-linear differential games and apply this methodology to a common-pool resource model of a lake where pollution corresponds to benefits and at the same time affects the ecosystem services. This paper studies the structure of optimal state-dependent taxes that steer the combined economic-ecological system towards the trajectory of optimal management, and provides an algorithm for calculating such taxes.
One of the major scientific and technological challenges for the production of flexible organic electronic devices is the device protection against atmospheric molecule permeation, which causes corrosion reducing its operation and lifetime. In this work, Spectroscopic Ellipsometry has been implemented to investigate the influence of silicon dioxide nanoparticles on the optical properties of hybrid polymers. The spectra analysis revealed valuable information about the electronic and vibrational response as well as the cross-linking mechanisms of these materials. The correlation of the optical properties with the synthesis parameters and the barrier response will contribute towards their optimization in order to be used as high barrier coatings for flexible organic electronics applications.
...Publications Consultations Application forms Vacancies Contact us About us Air Climate change Flooding Live flood warnings Flood map How to use it About the ...map View the map FAQs Contact us & Feedback Flooding: who does what? Flood warning - what we do Floodline Warnings Direct Flood ...risk Being prepared FAQs Floodline kids Flooding publications External links Business & Flood Risk Seminar Contact us Land Planning Radioactive substances Waste Water ... You are here: Home Page Flooding Flood map View the map View the map: terms and conditions Important information about ...
...A-Z list of ESDS guides Economic and Social Data Service - User support - ESDS guides | Home | A-Z index ...uk Telephone: +44 (0)1206 872143 Fax: 01206 872003 Print-friendly page A-Z list of ESDS guides Printing tips Printing tips The majority of these guides are web pages with a ... To print these guides at their best: select 'print friendly' at the top-right of the content of the page go to File/...via Beyond 20/20 WDS Advice for new users Analysing Change Over Time: A guide to ESDS resources CommonGIS functionality guide Countries and Citizens: Linking ...
... A better understanding of the links between nutrients, the gut microbiome and the intestinal immune system is likely to pave the way to the development of innovative approaches that target activation of specific immunological pathways for promoting the hostrsquo;s gut defense. Such knowledge should positively impact on the development of vaccine formulations and intervention strategies for improved control of enteric infections in developing countries. Registration fees # The Registration Fee is $715.00 on and before September 7, 2011. # After September 7, 2011, the ...
Smooth and notched specimens of the bearing steel 100Cr6 (SAE 52100) in a bainitic condition were used to determine the S-N-curves under tensile, torsional and combined in- and out-of-phase loading. In the area of high-cycle-fatigue, crack initiation was most likely caused by inclusions like Titanium Carbonitrides or Aluminium Oxides. A model was developed to describe the influence of the magnitude of these inclusions on the lifetime. A weakest link model, using the statistical distribution of inclusions and surface flaws, was used to describe the fatigue limit. (orig.)
Artificial Neural Networks (ANNs) are parallel distributed processing machines. The unique characteristics of ANNs are: Fault tolerance, robustness, plasticity and generalization. These offer great potential in many AI applications such as character recognition. Handwritten character recognition is an intrinsically interesting problem, but the difficulties of this task are the many variations in the characters. A robust new incremental learning method, which combines supervised and unsupervised learning paradigms implemented by the Functional Link Net, is illustrated with experimental results. Clustering, based on unsupervised learning, classifies the input data into several categories. The supervised learning paradigm then further classifies the data in the clustered categories.
The Idaho National Laboratory (INL) Ten-Year Site Plan (TYSP) describes the strategy for accomplishing the long-term objective of transforming the laboratory to meet Department of Energy (DOE) national nuclear research and development (R&D) goals, as outlined in DOE strategic plans. The plan links R&D mission goals and INL core capabilities with infrastructure requirements (single- and multi-program), establishs the 10-year end-state vision for INL complexes, and identifies and prioritizes infrastructure needs and capability gaps. The TYSP serves as the basis for documenting and justifying infrastructure investments proposed as part of the FY 2013 budget formulation process.
This invention concerns a hydraulic braking system for loads subjected to impacts and vibrations. These double acting telescopic type hydraulic braking systems possess significant drawbacks linked to possibly important hydraulic leaks due to (a) the use of many dynamic seals in such appliances and (b) the effects of the environment of the system on these seals, particularly when employed in nuclear power stations where the seals reach significant temperatures and are subjected to radiation. Under this invention a remedy is suggested to such drawbacks by integrating means to offset automatically the leaks and the accumulation of hydraulic fluid expansions, as well as facilities to show if such leaks have occurred.
The combination of wood gasification and high temperature fuel cells like solid oxide fuel cells (SOFC) is an interesting approach to achieve high electrical efficiencies (40%) in small scale combined heat and power plants. This combination is called 'Biomass - Integrated Gasification Fuel Cell System' (B-IGFC). The main challenge is the adjustment of the three main components gasification, gas cleaning and fuel cell. In this technology, the first proof of principle by combining a gasifier with a SOFC in a laboratory scale for more than 100 hours was achieved. During this period, no deactivation of the system was found. (author)
This paper describes the study of kinetically controlled enzymatic coupling of N- and O-glycopeptide fragments using subtilisin BPN' and two of its variants developed for use in high concentrations of dimethylformamide and in aqueous solution, respectively. Glycosyl amino acids were exploited as the P[sub 1], P[sub 2], P[sub 3], P'[sub 1], P'[sub 2], or P'[sub 3] residue in the enzymatic coupling. Glycosyltransferase-mediated glycosylation of the glycopeptide fragments obtained prior to or after enzymatic peptide bond formation is demonstrated. 19 refs., 5 figs., 1 tab.
A problem of the catalytic activity definition for metals, binary metallic alloys, and semiconductor materials is considered within new quantum mechanical and electrodynamics approach in the electron theory of catalysis. The quantitative link between the electron structure parameters of the materials and their catalytic activity on example of simple model reactions of the following type are found: H = H+ + e, O2 + e- = O2-. Copyright 2009 Wiley Periodicals, Inc. Int J Quantum Chem, 2009
The curves that describe the M-theoretic extension of type IIA string configurations with non-supersymmetric field theories on their surface exhibit a duality map. The map suggests a continued link between an SU(N) gauge theory with F flavors and an SU(F{minus}N) gauge theory with F flavors (the duality of supersymmetric QCD) even when the gaugino mass is taken to infinity. Within the context of the field theory such a duality only continues to make sense if the scalar fields remain light. We discuss the difficulties of decoupling the scalars within this framework. thinsp {copyright} {ital 1998} {ital The American Physical Society}
Within the framework of the EU power plant conceptual study (PPCS), a modular He-cooled divertor concept with integrated pin array (HEMP) is being developed at the Forschungszentrum Karlsruhe. The design goal is to achieve a high heat flux of at least about 10-15 MW/m"2, which is proposed for a near-term reactor model like DEMO. The development and optimization of the divertor concept require a close link between the main issues: design, analyses, materials and fabrication technology, and experiments with feedbacks between them to be accounted for. Design-specific requirements on materials and fabrication issues will be discussed.
It is possible to create nomographs similar to Fig. 2.10 to characterise damage potential of candidate time histories, provided there exists extensive records of earlier time-histories and the damage that they have caused. Thus in order to create such nomographs, one needs the correlated documentation between the input to the structure and the resulting damage. In order to use the Response-Spectra approach, one needs good statistical description of the input to the system. Extensive literature exists on both these methods. The MAC method that has being developed for the present research has yet to be validated. However, if it is successful, it would provide a valuable link between the SEA method and the rational method.
Crystal structure of monoclinic telluric acid ammonium phosphate (TAAP) has been studied by an X-ray diffraction method in the paraelectric phase at 333 K and in the ferroelectric phase at room temperature. It is confirmed that the space group in the paraelectric phase is P2/n. Comparison of the results between the two temperatures suggests that the plane which is made by the PO{sub 4} tetrahedron linked by hydrogen bonds has an important role for the ferroelectric phase transition. This plane is almost parallel to the direction of spontaneous polarization.
A high voltage self-blowing circuit breaker with closing resistors is equipped with an auxiliary contact inserted in the trip control circuit of an electrical circuit breaker. The auxiliary contact is actuated by the mechanical control rod of the circuit breaker in such a way as to prevent any operator closing error. A high-speed mechanism is inserted in the link system connecting the control rod and the auxiliary contact, with dead travel to delay closing of the auxiliary contact when a closing operation takes place and to prevent a tripping order from being transmitted too early. Such an early transmission would be liable to cause a flashover on the inserter contacts and damage to the circuit breaker.
This is the homepage of "an Australian multi-university collaboration undertaking research on the fundamental physics and technology of building, at the atomic level, a solid state quantum computer in silicon together with other high potential implementations." Although attempts to develop a quantum computer have met with limited success, the centre has substantial resources invested in advancing toward practical uses of quantum computing technology. The site provides a very good introduction to the principles and implications of quantum computing, as well as details about various research projects underway at the Australian universities. Links to conference and journal papers produced by members of the centre, many from 2003, are also provided.
...CanCom Dermatology Image Bank Dermatology Online Atlas Introduction to Skin Cancer Malignant Melanoma Skin Cancer (Not Melanoma) Comments: bubl@bubl.ac.... Covers anatomy, melanoma, infections, and dermatological disorders in AIDS. Author: University of Utah ...994 Resource type: document Malignant Melanoma This leaflet on malignant melanoma covers early detection, causes, clinical signs and symptoms, and provides ...9 Resource type: document Skin Cancer (Not Melanoma) Information on basal cell and squamous cell skin cancers. Author: ...
We study uncertainties surrounding competition on business networks and board games. We investigate these uncertainties using concepts of fuzzy logic and game theory. We investigate how the payoff of the players is affected by a number of factors. These include the level of connectivity or number of links, the number of competitors, possible constraints on the networks and on the boards, as well as choice of strategy adopted by competitors. We introduce one fuzzy player in the game. This player uses fuzzy rules to make strategic decisions. We introduce learning to train and analyze how the fuzzy player adapts over time during the game.
Ubiquitous computing based on small mobile devices using wireless communication links is becoming very attractive. The computational power and storage capacities provided allow the execution of sophisticated applications. Due to the fact that sharing of information is a central problem for distributed applications, the development of self organizing middleware services providing high level interfaces for information managing is essential. ADS is a directory service for mobile ad-hoc networks dealing with local and nearby information as well as providing access to distant information. The approach discussed throughout this paper is based upon the concept of information markets.
In this paper we dealt with the comparison and linking between lexical resources with domain knowledge provided by ontologies. It is one of the issues for the combination of the Semantic Web Ontologies and Text Mining. We investigated the relations between the linguistics oriented and domain-specific semantics, by associating the GO biological process concepts to the FrameNet semantic frames. The result shows the gaps between the linguistics-oriented and domain-specific semantics on the classification of events and the grouping of target words. The result provides valuable information for the improvement of domain ontologies supporting for text mining systems. And also, it will result in benefits to language understanding technology.
In this paper, the analysis of carbonate depositional systems, using high resolution sequence stratigraphy, studies the ratio between change in accommodation space and skeletal carbonate production. This approach establishes the concurrent change in nature of facies belts (expansion, retraction and type) and fossil communities, within the detailed time frame in accommodation. Carbonate production is generally considered to be a fairly simple function of environmental conditions such as climate and water depth. However, data from several case studies also show a covariance between change in stratigraphic architecture of carbonate systems (the seaward or landward stepping stacking patterns of stratigraphic units) and charge in facies. Case studies include Carboniferous algal mound development in the Paradox Basin (USA), Devonian stromatoporoid reef development in Alberta (Canada), and Cenomanian rudistid shoal development in Oman. The hypotheses are tested on cases taken from the ...
The paper begins with an introduction on the reasons that lead to the use of HVDC submarine cable links. The main aspects for the choice of direct current are presented as well as the advantages deriving from the utilization of submarine cables. The second part is dedicated to a discussion on the various type of insulation that could be used in power cables and their possible application to HVDC submarine cables. In the following there is a description of the main characteristics and technical details of some particular project that at present time (1995) are in progress. Two projects are briefly presented: Spain-Morocco, a 26 km long interconnection for the transmission, in a first phase, of 700 MW from Spain to Morocco at 400 kV a.c. by means of three cables, plus one spare, of the fluid filled type. The cables are designed for a future change to d.c. 450 kV, allowing a transmission of 500 MW each (i.e., 2 GW total). One of the peculiarities of the ...
When preadipocytes differentiate into adipocytes, several differentiation-linked genes are activated. Lipo-protein lipase (LPL) is one of the first genes induced during this process. To investigate early events in adipocyte development, we have focused on the transcriptional activation of the LPL gene. For this purpose, we have cloned and fused different parts of intragenic and flanking sequences with a chloramphenicol acetyltransferase reporter gene. Transient transfection experiments and DNase I hypersensitivity assays indicate that several positive as well as negative elements contribute to transcriptional regulation of the LPL gene. When reporter gene constructs were stably introduced into preadipocytes, we were able to monitor and compare the activation patterns of different promoter deletion mutants at selected time points representing the process of adipocyte development. We could delimit two cis-regulatory elements important for gradual activation of the ...
Purpose. To report a comparative prospective long-term functional analysis after Riboflavin UV A corneal cross-linking (CXL) in three different age groups of patients affected by progressive keratoconus (KC). Methods. Functional analysis comprised paediatric patients (?18 years) included 152 eyes (29.5%); intermediate group (19-26 years) 286 eyes (55.4%), and adults (?27 years) 78 eyes (15.1%). CXL was performed according to the Siena protocol by using the Vega CBM (Caporossi-Baiocchi-Mazzotta) X linker (CSO, Florence, Italy) at Siena University by the same authors. Pre- and post-op examinations included UCVA, BSCVA, corneal topography, and surface aberrometry (CSO Eye Top, Florence, Italy), at 48 months followup. Results. At 48 months followup paediatrics, intermediate, and adult patients showed a mean gain in UCVA of +0.2, +0.14 and +0.12 Snellen lines. BSCVA gained by a mean of +0.21, +0.2, and +0.1 Snellen lines. K(max) was reduced by a mean value of -0.9?D, ...
Clinical and hormonal indices of androgenic activity were compared in 118 males chronically intoxicated with alcohol. The population was divided into two groups with respect to their clinical and hormonal androgenic indices: 76 patients with (Group 1), and 46 patients without (Group 2) androgenic insufficiency. Distinct signs and syndromes of alcohol addiction were shown to correlate with the extent of cross-regulation impairment within hypothalamo-hypophyseo-gonadal system. This was particularly derived from comparison of clinical picture of chronic alcohol intoxication and hormone activity in the groups. Conventional therapy failed to restore the neuroendocrine indices that was apparently due to inhibition of cross-regulation links in the hypothalamo-hypophyseo-gonadal system at several stages of alcohol addiction. PMID:3223149
The authors made peritoneal dialisis with 5% of glucose (7 ml/kg of body weight) in 11 dogs under the conditions of an acute experiments. They examined cortiosl and ADH activity, hematocrite and plasma protein in the samples of blood, obtained on the 20th and 50th minute. ADH was titrated biologicaly by a new method, proposed by Nacev. The results were compared with the changes in the circulatory and renal indices, obtained at the same procedure in the preceding investigations. There was an increase in the cortisol and ADH activity, which could be explained by the total hypovolemia, induced by peritoneal dialisis. The increase of the cortisol level is described as a separate link in a more complex mechanism, assuring metabolic homeostasis. PMID:1222705
A web-based decision support tool, zone mapping application for precision farming (ZoneMAP, External Reference Not Shown ), has been developed to automatically determine the optimal number of management zones and delineate them using satellite imagery and field data provided by users. Application rates, such as of fertilizer, can be prescribed for each zone and downloaded in a variety of formats to ensure compatibility with GPS-enabled farming equipment. ZoneMAP is linked to Digital Northern Great Plains, a web-based application which hosts an archive of satellite imagery, as well as high resolution imagery from airborne sensors. Management zones created by ZoneMAP mapped natural variation of the soil organic matter and other nutrients relatively well and were consistent with zone maps cre...
Abstract Over the last 7 years, the AIMTech Research Group in the University of Leeds has used cultural-historical activity theory (CHAT) to inform a range of research activities in the fields of information behavior and information systems. In this article, we identify certain openings and theoretical challenges in the field of information behavior, which sparked our initial interest in CHAT: context, technology, and the link between practice and policy. We demonstrate the relevance of CHAT in studying information behavior and addressing the identified openings and argue that by providing a framework and hierarchy of activity-action-operation and semantic tools, CHAT is able to overcome many of the uncertainties concerning information behavior research. In particular, CHAT provides resear...
Quivers (directed graphs) and species (a generalization of quivers) and their representations play a key role in many areas of mathematics including combinatorics, geometry, and algebra. Their importance is especially apparent in their applications to the representation theory of associative algebras, Lie algebras, and quantum groups. In this paper, we discuss the most important results in the representation theory of species, such as Dlab and Ringel's extension of Gabriel's theorem, which classifies all species of finite and tame representation type. We also explain the link between species and K-species (where K is a field). Namely, we show that the category of K-species can be viewed as a subcategory of the category of species. Furthermore, we prove two results about the structure of the tensor ring of a species containing no oriented cycles that do not appear in the literature. Specifically, we prove that two such species have isomorphic tensor rings if and ...
Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurobehavioral disorder affecting 5% to 10% of children. Although considered to be a highly familial disorder, ADHD heritability estimates of 60% to 80% highlight the considerable role that environmental factors may still play in disorder susceptibility. Proposed ADHD environmental risk factors include prenatal substance exposures, heavy metal and chemical exposures, nutritional factors, and lifestyle/psychosocial factors. This paper reviews the literature published in 2010 investigating the association between environmental risk factors and ADHD or related symptomatology. Sources of risk factor exposure and the proposed mechanism by which each exposure is linked to ADHD-related neurobehavioral changes are also reported. Metho...
Our investigation concerns the class of Josephson-like systems, sharing the same nonlinear Hamiltonian. Among the latter a Josephson junction with an external biasing circuit is considered. We diagonalize the fully nonlinear Hamiltonian (in the superconductive regime of the junction) in the Fock space of the TBHA (two-boson Heisenberg algebra) and prove that such algebra leads quite naturally to the theoretical realization of codewords and logical operators: the codewords are defined as the even and odd coherent states of the TBHA, while the logical operators are expressed in terms of operators in the same algebra. Our theoretical construction corresponds to a continuous variable quantum computation scheme; the continuous variables are identified in terms of the physical operators of the junction. The link between this scheme and the technique of fermionization of bosonic systems is also discussed.
A numerical and experimental investigation is carried out in a solar thermochemical reactor for the thermal dissociation of ZnO at 2000 K using concentrated solar energy. The reactor consists of a cavity-receiver lined with ZnO particles and directly exposed to high-flux irradiation. A transient heat transfer model is formulated to link the rate of radiation, convection, and conduction heat transfer to the reaction kinetics. The radiosity and Monte Carlo methods are applied to obtain the distribution of net radiative fluxes at the internal surfaces of the reactor cavity and at the surface of the ZnO bed. Validation is accomplished in terms of the calculated and measured transient temperature profiles and chemical reaction rates.
ObjectiveTo characterize global structural features of large-scale biomedical terminologies using currently emerging statistical approaches.DesignGiven rapid growth of terminologies, this research was designed to address scalability. We selected 16 terminologies covering a variety of domains from the UMLS Metathesaurus, a collection of terminological systems. Each was modeled as a network in which nodes were atomic concepts and links were relationships asserted by the source vocabulary. For comparison against each terminology we created three random networks of equivalent size and density.MeasurementsAverage node degree, node degree distribution, clustering coefficient, average path length.ResultsEight of 16 terminologies exhibited the small-world characteristics of a short average path le...
The human genome encodes 11 cysteine cathepsins belonging to the papain-like family of cysteine peptidases that are known predominantly as endo-lysosomal enzymes. However, it is now understood that the functions and activities of cysteine cathepsins are not limited to endo-lysosomal compartments, as they are also active in the peri- and extracellular space. The thyroid gland is an endocrine organ where such intra- and extracellular proteolytic activities are required to solubilize the prohormone thyroglobulin from its luminal, covalently cross-linked storage forms for subsequent processing into smaller protein fragments and thyroid hormone liberation. Cathepsin K has been identified as one of the cysteine cathepsins with a crucial role in thyroglobulin processing. However, cathepsin K has ...
In virtually all forms of life on earth, proteins in each cell are made according to a genetic blueprint, in the form of DNA. The translation of copies of this genetic blueprint (in the form of messenger RNA) into polypeptides is performed on the ribosome, a highly complex molecular machine composed of RNAs and proteins. To this end, special adaptor molecules called transfer RNAs are lined up by the ribosome in the sequence dictated by the genetic code, such that the amino acids carried by these molecules can be linked into a polypeptide. Several cofactors are involved in these processes, some of which require energy freed up by GTP hydrolysis. Although the ribosome was discovered more than 50 years ago, its structure has only been solved recently by X-ray crystallography. Another technique, cryo-electron microscopy, is starting to contribute toward our understanding of the ribosome's function, by portraying its conformational changes and binding ...
Four-enzyme section of the shikimate pathway (Aro B, D, E, and K) of Streptococcus pneumoniae has been studied. Kinetic properties of the individual enzymes and three- and four-enzyme linked reactions have been characterized in vitro. On the basis of the data measured in spectrophotometric and LC-MS experiments, kinetic mechanisms of the enzymes have been suggested and all kinetic parameters have been identified. Kinetic models for these three- and four-enzyme sections of the shikimate pathway have been constructed and validated. The model of the four-enzyme section of shikimate pathway has been employed to design an inhibition-sensitive reconstituted pathway for a high-throughput screening effort on the shikimate pathway. It was demonstrated that using the model it was possible to optimize this reconstituted pathway in such a way to provide equal sensitivity of the enzymes to inhibition. PMID:16921527
Abstract The Hippo pathway is an evolutionally conserved protein kinase cascade involved in regulating organ size in vivo and cell contact inhibition in vitro by governing cell proliferation and apoptosis. Deregulation of the Hippo pathway is linked to cancer development. Its first core kinase Warts was identified in Drosophila more than 15 years ago, but it gained much attention when other core components of the pathway were identified 8 years later. Major discoveries of the pathway were made during past several years. The core kinase components Hippo, Salvador, Warts, and Mats in the fly and Mst1/2, WW45, Lats1/2, and Mob1 in mammals phosphorylate and inactivate downstream transcriptional co-activators Yorkie in the fly, Yes-associated protein (YAP) and transcriptional co-activator with ...
It has often been argued that the success and spread of modern humans 50,000years ago was due to a series of key behavioral shifts that conferred particular adaptive advantages. And yet, particularly during the African Middle Stone Age (MSA), some of these "modern" behaviors see only patchy expression across time and space. Recent models have proposed a link between the emergence of modern behaviors and environmental degradation and/or demographic stress. Under these models, modern behaviors represent a form of social/economic intensification in response to stress; if this were the case, signs of subsistence intensification should be more common during periods in which these behaviors are manifested than when they are not. In order to test these models, I analyzed faunal remains from Sibud...
Previous family and twin studies have indicated that Graves' disease has a heritable component. Family studies have also shown that some autoimmune disease cluster in families and genetic studies have been able to show shared susceptibility genes. In the present nation-wide study we describe familial risk for Graves' disease among parents and offspring, singleton siblings, twins and spouses with regard to age of onset, gender and number and type of affected family members. Additionally familial association of Graves' disease with any of 33 other autoimmune and related conditions was analyzed. The Swedish Multigeneration Register on 0-75-year-old subjects was linked to the Hospital Discharge Register from years 1987-2007. Standardized incidence ratios (SIRs) were calculated for individuals ...
How do people understand questions about cause and prevent? Some theories propose that people affirm that A causes B if A's occurrence makes a difference to B's occurrence in one way or another. Other theories propose that A causes B if some quantity or symbol gets passed in some way from A to B. The aim of our studies is to compare these theories' ability to explain judgements of causation and prevention. We describe six experiments that compare judgements for causal paths that involve a mechanism, i.e. a continuous process of transmission or exchange from cause to effect, against paths that involve no mechanism yet a change in the cause nevertheless brings about a change in the effect. Our results show that people prefer to attribute cause when a mechanism links cause to effect. In contr...
The Authenticated Tracking and Monitoring System (ATMS) has been designed to address the need for global monitoring of the status and location of proliferation-sensitive items. Conceived to utilize the proposed Global Verification and Location System (GVLS) satellite link, ATMS could use the existing International Maritime Satellite commercial communication system until GVLS is operational. The ATMS concept uses sensor packs to monitor items and environmental conditions, collects a variety of events data through a sensor processing unit, and transmits the data to a satellite, which then sends data to ground stations. Authentication and encryption algorithms will be used to secure the data. A typical ATMS application would be to track and monitor the safety and security of a number of items in transit along a scheduled shipping route. This paper also discusses a possible proof-of-concept system demonstration.
Early technical history of electric supply to electric railways is briefly reviewed as an introduction to the following seven papers included in this special issue on technologies for saving energy in railway operation. Continuous power supply played a significant role in the early history of railway technologies. The variable voltage variable frequency (VVVF) power electronic technology had also a substantial impact on railway traction systems after 1980s. VVVF technology made it possible to have more efficient drives, downsize rolling stocks, and develop regenerative brakes. Because detailed discussions on each technical development are presented in the following papers, the general remarks of those technologies made in this introduction provide logical links to the ideas presented in th...
An enantiocontrolled route to aziridinomitosenes had been developed from l-serine methyl ester hydrochloride. The tetracyclic target ring system was assembled by an internal azomethine ylide cycloaddition reaction based on silver ion-assisted intramolecular oxazole alkylation and cyanide-induced ylide generation via a labile oxazoline intermediate (62 to 66). Other key steps include reductive detritylation of 26, methylation of the N-H aziridine 56, oxidation of the sensitive cyclohexenedione 68 to quinone 70, and carbamoylation using Fmoc-NCO. Although the aziridinomitosene tetracycle is sensitive, a range of protecting group manipulations and redox chemistry can be performed if suitable precautions are taken. A study of DNA alkylation by the first C-6,C-7-unsubstituted aziridinomitosene 11a has been carried out, and evidence for DNA cross-link formation involving nucleophilic addition to the quinone subunit is described. PMID:14677970
Introduction.Microfluidic technology allows fast reactions in a simple experimental setup, while using very low volumes and amounts of starting material. Consequently, microfluidic technology is an ideal tool for radiolabeling reactions involving short-lived positron emitters. Optimization of the complex array of different reaction conditions requires knowledge of the different reaction parameters linked to the microfluidic system as well as their influence on the radiochemical yields. 1-(5-Deoxy-5-fluoro-?-d-arabinofuranosyl)-2-nitroimidazole ([18F]FAZA) is a frequently used radiotracer for PET imaging of tumor hypoxia. The present study describes the radiosynthesis of [18F]FAZA by means of microfluidic technology and subsequent small animal PET imaging in EMT-6 tumor-bearing mice.Methods...
The new generation of performing rechargeable lithium-ion batteries (``rocking-chair``-type) are penalized by important self-output phenomena linked with the use of highly oxidizing positive electrodes. In order to limit this problem in LiMn{sub 2}O{sub 4}/C batteries, two different passivation techniques were used in order to limit the surface contact between the positive electrode and the electrolyte. Thanks to these treatments, a significant reduction of the percentage of irreversible capacity losses is effectively observed. (J.S.) 3 refs.
Abstract Superoxide dismutase (SOD) is ubiquitous in aerobic organisms and constitutes the first link in the enzyme scavenging system of reactive oxygen species. In the present study, species and organ diversity of SOD activity in a solution and in an in-gel assay system, as well as the effects of hydrogen peroxide (H2O2) on SOD activity, were investigated. In a solution assay system, SOD activity of jackfruit root, shoot, leaves, axes, and cotyledons, of maize embryos and endosperms, of mung bean leaves and seeds, of sacred lotus axes and cotyledons, and of rice and wheat leaves was increased by 1-15 mmol/L H2 O2. However, SOD activity in rice root and seeds, maize roots and leaves, mung bean roots and shoots, and wheat seeds was decreased by 1-15 mmol/L H2O2. The SOD activity of wheat ro...
Soluble starch?based biodegradable and microporous microspheres (SDM-Ms) were prepared by emulsion chemical cross-linking technique using trisodium trimetaphosphate (TSTP) as the cross-linker. The resultant amorphous SDM-Ms were excellently identified by scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). The internal rupture and surface-controlled erosion were the predominant degradation mechanisms for SDM-Ms. The obtained SDM-Ms were applied to adsorb coix seed oil (CSO) by immersing method. The adsorption capacity of CSO within SDM-Ms was determined, namely 0.5238?g/g, and the thermal stability was shown higher than that of the free CSO. A burst release appeared in the second hour, followed by controlled release. Diffusion, d...
We discuss the foundations of factor or regression models in the light of the self-consistency condition that the market portfolio (and more generally the risk factors) is (are) constituted of the assets whose returns it is (they are) supposed to explain. As already reported in several articles, self-consistency implies correlations between the return disturbances. As a consequence, the alpha's and beta's of the factor model are unobservable. Self-consistency leads to renormalized beta's with zero effective alpha's, which are observable with standard OLS regressions. Analytical derivations and numerical simulations show that, for arbitrary choices of the proxy which are different from the true market portfolio, a modified linear regression holds with a non-zero value $\\alpha_i$ at the origin between an asset $i$'s return and the proxy's return. Self-consistency also introduces ``orthogonality'' and ``normality'' conditions linking the beta's, alpha's (as well as ...
High angle conveyor (HAC) systems in open pit mining offer many advantages over the traditional, truck only, haulage systems, including: (1) superior energy efficiency, (2) less dependency on petroleum products, (3) less sensitivity to inflation, (4) less labor, (5) less excavation for the amount of ore recovered, and (6) less ramp construction and maintenance costs. Previous studies have revealed the technical and economic feasibility of high angle conveyors. The present paper introduces the Continental Conveyor sandwich belt HAC as the vital link to optimization of in-pit conveying systems. A test and demonstration unit, has been built and demonstrated. Discussion continues with the HAC systems to suit the various open pit mining operations and the corresponding characteristics of the system components, particularly the high angle conveyor. The range of HAC systems is discussed. (11 refs.)
Today?s demand on high supply chain performance requires higher awareness about supply chain risks and uncertainty. The purpose of this paper is to analyse the role of temporary storage in the transport network in a supply chain perspective. The primary research question concerns the purpose or role of temporary storage and whether management of temporary storage can contribute to reducing risks and uncertainty in the supply chain. The research is based on a system-theoretical approach, which emphasizes a holistic view instead of the characteristics of the different parts. The research method used in this paper is abductive. Existing theories are used to formulate a framework which leads to a conceptual model description of the temporary storage function. This model is then supported and v...
Purpose - This paper aims to explore the links between revenue management and business-to-business (B2B) relationships and explains how revenue management can both support and damage B2B relationships. Design/methodology/approach - A single case study method was employed to conduct qualitative research into a company and its key accounts. In-depth data were collected from three divergent sources (company revenue managers, company account managers and nine of the company's key accounts) through semi-structured interviews, observations and document studies. Findings - The research findings reveal that from the company's perspective, managers acknowledge that revenue management has positively influenced the process of identifying and analysing key account activities and conducting contractual...
Ten children receiving maintenance dialysis were immunized with the standard dose of measles-mumps-rubella vaccine between 15 and 33 months of age. Immune responses to vaccination were determined using commercially available enzyme-linked immunosorbent assays for measles, mumps, and rubella viruses. Eight children responded to measles vaccine, 5 to mumps vaccine, 8 to rubella vaccine, and only 3 children to all three vaccines, compared with a seroconversion rate of over 90% to all three vaccines in healthy children (P less than 0.0001). We contend that the relatively poor immunocompetence of our dialysis patients explains their less than optimal vaccine response and suggest that children vaccinated while undergoing dialysis be tested to confirm serological evidence of immunity. PMID:1571219
The efficient design of computation intensive multidimensional signal processing applications requires dealing with three kinds of constraints: those implied by the data dependencies, the non-functional requirements (real-time, power consumption) and resources availability of the execution platform. Modeling and Analysis of Real-time and Embedded systems (MARTE) UML profile through its repetitive structure modeling (RSM) package is well suited to model the inherent parallelism within these applications, a compact representation of parallel execution platforms and the distributive mapping of one on another. The execution of such a specification respects the whole set of constraints defined upon, while the quality of the scheduling is directly linked to the quality of the mapping of the mult...
The history of the political process surrounding regulations is traced from the 1930s, when the natural gas industry and the Federal Power Commission were in their infancy. The author traces the changing mandate that Congress has provided the regulators and the instincts for self-preservation that these bureaucrats have manifested when they suspected a change in presidential administration or a new decision from the Supreme Court. Natural gas has been one political issue that has split Congress by region. The economic interests of producer and consumer states have often been at such odds that regulation has involved the question of redistribution of wealth among regions as well as between households and industry. The picture is complicated by the link between gas production and distribution and the production and distribution of coal and oil. 12 figures, 25 tables.
Reference failures, and their increase in affectively negative conditions (known as affective reactivity of speech), are more frequently observed in schizophrenia patients than in normal controls, but no information is available comparing schizophrenia with depression, ie, a mental disorder closely linked to the concept of affective reactivity. To address this gap in the literature, the present study compared 24 schizophrenia inpatients, 21 unipolar depression inpatients and 21 normal controls. Two 10-minute conversational speech samples (1 on negative and 1 on positive memories) were collected from each patient. The transcripts of the audiotaped interviews were analyzed blindly for frequencies of 6 types of referential failures, employing the Communication Disturbances Index, adapted for ...
In a fluoroscopic imaging system, image quality and patient dose are both affected by the optical system linking the image intensifier with the video camera. The effect on patient exposure of increasing the optical iris aperture size over that required for other procedures performed on the same imaging system was investigated for the air-contrast barium enema examination. Using a large-area transmission ionisation chamber to monitor the Roentgen-area-product of entrance exposure, a decrease in fluoroscopic radiation of greater than 50% was clinically documented for a fluoroscopic system utilising kVp and mA variable automatic brightness control. For this iris change, the video image was of acceptable quality for positioning and monitoring the patient, and no deleterious effect was detected in the conduct of the air-contrast exam. The availability of a variable-sized operator-selectable iris diaphragm would permit this dose-reduction approach to be extended to other ...
Analytical methods developed to sample and characterize ambient organic aerosols often face the trade-off between long sampling times and the loss of detailed information regarding specific chemical species present. In the work presented here, high-time resolution ambient measurements (3.5 minutes) are achieved by using the Photoionization Aerosol Mass Spectrometer (PIAMS) in conjunction with the mini-Versatile Aerosol Concentration Enrichment System (m-VACES). Aerosol sampling took place for one week at State of Delaware Air Quality Monitoring Site in Wilmington, Delaware in June 2006. The soft, universal ionization scheme of PIAMS allows for identification of various chemical compounds by a signature ion, often the molecular ion. Meteorological data was used to link some species, such as...
Recent research findings of epidemiologist Alice Stewart suggest that nuclear workers may be at risk of contracting cancer even though their measured occupational doses fall within current safety standards. It is argued that these standards are inappropriate as they are based on extrapolations of studies on survivors of the Hiroshima and Nagasaki explosions. These individuals received single doses of radiation, whereas today's nuclear industry personnel are exposed to low-level ionizing radiation over the length of their working lives. Stewart's team linked low dose occupational exposure to ionizing radiation with an increased risk of cancer in respiratory, digestive and blood-forming tissues. The nuclear industry and United States government agencies hotly contest these assertion with their potentially damaging political and economic consequences. (UK).
Recent research findings of epidemiologist Alice Stewart suggest that nuclear workers may be at risk of contracting cancer even though their measured occupational doses fall within current safety standards. It is argued that these standards are inappropriate as they are based on extrapolations of studies on survivors of the Hiroshima and Nagasaki explosions. These individuals received single doses of radiation, whereas today's nuclear industry personnel are exposed to low-level ionizing radiation over the length of their working lives. Stewart's team linked low dose occupational exposure to ionizing radiation with an increased risk of cancer in respiratory, digestive and blood-forming tissues. The nuclear industry and United States government agencies hotly contest these assertion with their potentially damaging political and economic consequences. (UK).
Electron beam (EB) processing involves using electrons to initiate polymerization or cross-linking reactions in suitable substrates, thereby enhancing specific physical and chemical properties. A relatively new use of EB processing is now emerging: the production of fibre-reinforced composites. EB curing at ambient temperature has the potential to reduce the residual stresses in an advanced composite, a result of expansion during thermal curing, and to significantly increase the overall cure speed and process throughput. Wood fibres are used as a filler material for various thermoplastics such as polypropylene. EB treatment, combined with selected EB-curable coupling agents, significantly increases the adhesion between the wood fibres and the thermoplastic polymer, resulting in improved material properties. Work to develop both products and processes for the EB curing of fibre-reinforced composites is currently underway at AECL Research. This paper briefly updates ...
The overall goal of this work is to design and optimize a biodiesel production process from soybean oil. To achieve this goal, several inter-connected activities were undertaken. First, an initial flowsheet for the process was synthesized. The performance of this flowsheet along with the key design and operating criteria were identified by conducting computer-aided simulation using ASPEN Plus. Various scenarios were simulated to provide sufficient understanding and insights and to select a base-case flowsheet. Next, mass and energy integration studies were performed to reduce the consumption of material and energy utilities, improve environmental impact, and enhance profitability. Capital cost estimation was carried out using the ICARUS Process Evaluator computer-aided tool linked to the r...
The development of the monitoring network for background measurements of air pollution in the USSR is noted. The use of paired stations, to aid in locating permanent sites as well as for determining the local component of background air pollution, is described. Thermoelectric actionometers with five glass filters are used to measure Shupp's turbidity coefficient for estimating extinction of solar radiation due to aerosols. Sampling and chemical analysis of precipitation uses methods developed during the International Geophysical Year. An intercomparison of meteorological instruments was carried out in the USSR in 1973 and 1978. The most stable actinometer was the Linke-Foisner device. Chemical analyses of precipitation made since 1958 in the USSR show increases in air pollution levels only in particular areas.
Physicians are exercising their responsibility as healers in their efforts to prevent nuclear war. Death for Hiroshima survivors was experienced in four stages: the immediate impact of destruction, the acute impact of radiation, delayed radiation effects, and later identification as an atomic bomb survivor. Each phase had its physical and psychological impacts and negates Hiroshima as a model for rational behavior despite those who claim survival is possible for those who are prepared. The psychic effects of modern nuclear, chemical, and germ warfare need to be challenged with a symbolization of life and immortality. Studies of psychological reactions to the terror children felt during practice air-raid drills indicate that the fears can be surpressed and re-emerge in adult life as a linking of death with collective annihilation. Other themes which emerge are feelings of impermanence, craziness, identification with the bomb, and a double existence. Psychic numbing ...
A novel composite charged mosaic membrane (CCMM) was prepared via interfacial polymerization (IP) of polyamine [poly(epichlorohydrin amine)] and trimesoyl chloride (TMC) on the polyethersulfone (PES) support. Fourier transform infrared spectroscopy (FT-IR), environmental scanning electron microscopy (ESEM), atomic force microscopy (AFM) and water contact angle analysis were applied to characterize the resulted CCMM. The FT-IR spectrum indicates that TMC reacts sufficiently with polyamine. ESEM and AFM pictures show that the IP process produces a dense selective layer on the support membrane. The water contact angle of the CCMM is smaller than that of the substrate membrane because of the cross-linked hydrophilic polyamine network. Several factors affecting the IP reaction and the performan...
Premnalatifolin A (1), a unique icetexane diterpene dimer was isolated from the stem-bark of Indian medicinal plant, Premna latifolia. Its structure and relative stereochemistry were elucidated on the basis of detailed spectroscopic analysis, including HRESIMS and 2D NMR (COSY, HSQC, HMBC, and NOESY) spectra. The compound has dimeric carbon skeleton composed of two icetexane skeletal diterpenes linked via ether bond. Further, premnalatifolin A (1) was also evaluated for its cytotoxicity against cancer cell lines (HT-29, A-431, MCF-7, Hep-G2, PC-3, A-549, B-16 F10, and ACHN), which displayed potent activity against HT-29 and MCF-7 cell lines with the IC50 values of 12.15 and 1.11mg/mL, respectively.
After irradiation at 254nm of aqueous solutions of the antipsychotic drug flupentixol, the structures of the photodegradation products were determined by ultra high performance liquid-chromatography linked to mass spectrometry. Fragmentation patterns of the parent ions were established on a hybrid linear ion trap-orbitrap mass spectrometer allowing accurate mass measurements of both parent and daughter ions. This allowed to propose plausible structures for the main photolysis products of flupentixol. A total of nine photoproducts were detected after irradiation of the drug. The main photoproduct is generated following the addition of a hydroxyl group on the double bond adjacent to the thioxanthene ring. Secondary photoproducts were also observed.
In 1946, the Philippines raised claims in the South China Sea over an area already known as Spratly Islands. This claim advanced through peculiar stages, starting when Thomas Cloma allegedly discovered islands in 1946, later named as Freedomland, and maturing to some extent in 1978 by the governments claim over the so-called Kalayaan Island Group. Considered as an oceanic expansion of its frontiers, this paper reviews the basis of the claim, first over the nature of Clomas activities, and secondly over the measures the Philippine government took as a reaction of Clomas claim of discovery of an area already known in western cartography as the Spratlys. Eventually, what is the nature of the link between the 1978 Kalayaan Islands Groups official claim and 1956 Clomas private one?
In this article we model a Global Navigation Satellite System (GNSS) in a Schwarzschild space-time, as a first approximation of the relativistic geometry around the Earth. The closed time-like and scattering light-like geodesics are obtained analytically, describing respectively trajectories of satellites and electromagnetic signals. We implement an algorithm to calculate Schwarzschild coordinates of a GNSS user who receives proper times sent by four satellites, knowing their orbital parameters; the inverse procedure is implemented to check for consistency. The constellation of satellites therefore realizes a geocentric inertial reference system with no \\emph{a priori} realization of a terrestrial reference frame. We show that the calculation is very fast and could be implemented in a real GNSS, as an alternative to usual post-Newtonian corrections. Effects of non-gravitational perturbations on positioning errors are assessed, and methods to reduce them are sketched. In particular, ...
Nomographs that calculate the threshold values of surface fire parameters which lead to crown fire initiation were created by linking two separate fire behavior models: Van Wagner?s crown fire ignition criteria and Byram?s surface fire model. The nomographs were also based on the existing surface (fuel load, fuel heat content) and canopy (foliar moisture content, live crown base height) fuel models of Aleppo (Pinus halepensis Mill.) pine forests of Mediterranean Greece. The most important fire parameters for crown fire initiation that are calculated by the nomographs are the critical flame length and the forward spread rate of the surface fire. These parameters are readily observable in the field during fires. The nomographs provide a judicious way to assess whether a crown fire is likely ...
BACKGROUND AND PURPOSE It is well established that cytochrome P450 2J (CYP2J) enzymes are expressed preferentially in the heart, and that ebastine is a substrate for CYP2J, but it is not known whether ebastine is metabolized in myocardium. Therefore, we investigated its pharmacokinetics in the rat isolated perfused heart. EXPERIMENTAL APPROACH Rat isolated hearts were perfused in the recirculating mode with ebastine for 130-min. The concentrations of ebastine and its metabolites, hydroxyebastine and carebastine, were measured using liquid chromatography with a tandem mass spectrometry. The data were analysed by a compartmental model. The time course of negative inotropic response was linked to ebastine concentration to determine the concentration-effect relationship. KEY RESULTS Ebastine w...
Ray tracing Monte Carlo calculations have been carried out using an existing Monte Carlo radiation transport code to obtain estimates of the microsave power exiting the torus coupling links in EPT microwave manifolds. The microwave power loss and polarization at surface reflections were accounted for by treating the microwaves as plane waves reflecting off plane surfaces. Agreement on the order of 10% was obtained between the measured and calculated output power distribution for an existing EBT-S toroidal manifold. A cost effective iterative procedure utilizing the Monte Carlo history data was implemented to predict design changes which could produce increased manifold efficiency and improved output power uniformity.
Male infertility, characterized by hypogonadism, decreased semen quality or ejaculatory dysfunction, accounts for approximately 20% of infertility cases. Obesity and metabolic dysfunction have been identified, among other causal factors, to contribute to male infertility. In the context of the Western world's `obesity epidemic', this article discusses three main biological mechanisms linking obesity to impaired male reproductive function: hypogonadism, testicular heat stress/hypoxia-induced apoptosis and endocrine disruption by `obesogens'. Among these, obesity-induced hypogonadism is undoubtedly the most clinically significant and is easily assessed. Rapidly expanding areas of research in this area include leptin modulation of kisspeptins and hypothalamic-pituitary-testicular hormone path...
The 50th anniversary of Mary Lyon?s 1961 Nature paper, proposing random inactivation in early embryonic life of one of the two X chromosomes in the cells of mammalian females, provides an opportunity to remember and celebrate the work of those involved. While the hypothesis was initially put forward by Lyon based on findings in the mouse, it was founded on earlier studies, notably the work of Susumu Ohno; it was also suggested independently by Beutler and colleagues using experimental evidence from a human X-linked disorder, glucose-6-phosphate dehydrogenase deficiency, and has proved to be of as great importance for human and medical genetics as it has for general mammalian genetics. Alongside the hypothesis itself, previous cytological studies of mouse and human chromosomes, and the obse...
In this study structural and magnetic character of the expanded austenite phase (gN) layer formed on a medical grade CoCrMo alloy by a low-pressure Radio-Frequency plasma nitriding process was investigated. The formation of the expanded austenite phase is facilitated at a substrate temperature near 400^oC for 1, 2, 4, 6 and 20h under a gas mixture of 60% N2-40% H2. The magnetic state of the gN layers was determined by a surface sensitive technique, magneto-optic Kerr effect (MOKE), and with a scanning probe microscope in magnetic force mode (MFM). Strong evidence for the ferromagnetic nature of the gN-(Co,Cr,Mo) phase is provided by the observation of stripe domain structures and the hysteresis loops. The ferromagnetic state for the gN phase observed here is mainly linked to large lattice ...
During the present project the mechanisms of generation of low frequency noise (LFN) for upwind rotors has been investigated. A 3.6 MW turbine has been simulated with a noise prediction model from NASA in US. Running the model on this turbine a number of important turbine design parameters with influence on the LFN have been identified as well as other parameters not linked to the turbine design. Of important parameters can be mentioned 1) rotor rotational speed, 2) blade/tower clearance, 3) rotor configuration - upwind/downwind, 4) unsteadiness/turbulence in inflow. Further, the directivity characteristics of LFN has been computed as well as reduction in noise as function of distance from the turbine. In general low levels of LFN has been computed for the upwind rotor in standard configuration. (au)
The BT-EdF-CEA consortium for the development and the performance improvement of lithium/polymer batteries has carried out a safety analysis of the industrial risk and the risk for users linked with this new technology. The process chosen for the manufacturing of lithium/polymer batteries does not generate any particular risk of personnel or environmental contamination. Security tests have permitted to observe and analyze the behaviour of 4 Ah elements during thermal shocks, perforation and crushing, and during external short-circuit on 20 Ah elements. These tests demonstrate the great thermal stability and the excellent behaviour of batteries in the case of partial destruction. (J.S.) 2 refs.
The objective of this work was to compare seasonal variations of reproduction physiology of the ragworm Nereis diversicolor -a key species in estuarine ecosystems-originating from a clean (Authie) and multi-polluted (Seine) estuaries. A particular attention was carried out in female worms, on relationships between sexual maturity stages, energy reserves (glycogen and lipids) and steroid hormone levels (progesterone, 17b-estradiol, and testosterone). Sexual maturity index (SMI), energy reserves and steroid hormones are clearly influenced by season in worms from both sites. Depleted steroid hormone levels were depicted in specimens exhibiting high sexual maturity stage and energy reserves. Intersite analysis has revealed all over the sampling period:-a sexual precocity in worms from Seine,-g...
This study looks at the land use impact of the biofuels expansion on both the intensive and extensive margin, and its environmental consequences. We link economic, geographical and environmental models by using spatially explicit common units of analysis and use remote sensing crop cover maps and digitized soils data as inputs. Land use changes are predicted via economic analysis of crop rotation choice and tillage under alternative crop prices, and the Environmental Policy Integrated Climate (EPIC) model is used to predict corresponding environmental impacts. The study focuses on Iowa, which is the leading biofuels hotspot in the U.S. due to intensive corn production and the high concentration of ethanol plants that comprise 28% of total U.S. production. We consider the impact of the biof...
We present evidence in favour of a link between the luminosity radiatively dissipated in the central engine of radio-loud Active Galactic Nuclei and the kinetic power in their jets. This piece of evidence is based on the relation we find between the luminosity in broad emission lines and the kinetic power in pc-scale radio jets, for a sample of radio-loud quasars for which suitable data are available in the literature. We find that the ionizing luminosity and the kinetic one are of the same order of magnitude, suggesting that the processes responsible for them are somehow related. A strong magnetic field in equipartition with the radiation field could be responsible for regulating both processes. BL Lac objects seem to follow a similar behaviour, but with comparatively fainter broad line emission.
This article investigates the missing link in the literature - whether informal institutions, or what is known as culture, can affect the level of financial development for a country? Our hypothesis stresses that the cultural dimensions of a country can have an impact on its financial set-up. We consider multiple dimensions of culture, identified in the literature by Tabellini (2008), to test our hypothesis. As culture evolves in the form of greater trust, control and other traits, individuals' attitudes towards financial market change, and they engage in greater financial transactions. This, in turn, leads to better financial development. Using quantile estimation technique for a cross section of 90 countries, we find that culture significantly influences the level of financial developmen...
The unavoidable irreversible losses of power in a heat engine are found to be of quantum origin. Following thermodynamic tradition a model quantum heat engine operating by the Otto cycle is analyzed. The working medium of the model is composed of an ensemble of harmonic oscillators. A link is established between the quantum observables and thermodynamical variables based on the concept of canonical invariance. These quantum variables are sufficient to determine the state of the system and with it all thermodynamical variables. Conditions for optimal work, power and entropy production show that maximum power is a compromise between the quasistatic limit of adiabatic following on the compression and expansion branches and a sudden limit of very short time allocation to these branches. At high temperatures and quasistatic operating conditions the efficiency at maximum power coincides with the endoreversible result. The optimal compression ratio varies from the square ...
The interaction energies between the different types of bases of a single strand of DNA molecule have been calculated. Using these original values of energies the harmonic behavior of a number of base patterns of DNA has been studied. In view of the great interest aroused by the discovery of the role of the telomere segment of the DNA in the replication process and its possible link with the aging process, we have investigated, with simple models, the harmonic behavior of the telomeric pattern of bases as well as the thermodynamic response in the biological system. With these results a conclusion on the probable role of the telomeric pattern on aging has also been drawn. Here the calculated values of harmonic frequencies of the telomeric pattern of bases and of other possible patterns show that the telomeric pattern is associated with the highest vibrational frequency among all patterns of base combinations at the replication end of DNA. This seems to suggest that ...
Culture-independent microbiological technologies that interrogate complex microbial populations without prior axenic culture, coupled with high-throughput DNA sequencing, have revolutionized the scale, speed and economics of microbial ecological studies. Their application to the medical realm has led to a highly productive merger of clinical, experimental and environmental microbiology. The functional roles played by members of the human microbiota are being actively explored through experimental manipulation of animal model systems and studies of human populations. In concert, these studies have appreciably expanded our understanding of the composition and dynamics of human-associated microbial communities (microbiota). Of note, several human diseases have been linked to alterations in th...
Background: Thyroid-stimulating autoantibodies (TSAb) bind to the thyrotropin receptor (TSHR) extracellular domain, or ectodomain (ECD), comprising a leucine-rich repeat domain (LRD) linked by a hinge region to the transmembrane domain (TMD). The LRD (residues 22???260; signal peptide 1???21) contains two disulfide-bonded loops at its N-terminus. In the crystal structure of the isolated LRD complexed with human TSAb monoclonal antibody (mAb) M22, N-terminal disulfide loop 1 (residues 22???30) could not be determined because of crystal disorder. Nevertheless, present crystal structure data are interpreted to exclude a role for the LRD N-terminal disulfide loops in the TSAb epitope(s), contradicting prior functional evidence of a role for these loops in TSAb function. Materials and Methods: ...
The Lesch-Nyhan (LN) syndrome is a severe X chromosome-linked disease that results from a deficiency of the purine salvage enzyme hypoxanthine phosphoribosyltransferase (HPRT). The mutations leading to the disease are heterogeneous and frequently arise as de novo events. The authors have identified nucleotide alterations in 15 independently arising HPRT-deficiency cases by direct DNA sequencing of in vitro amplified HPRT cDNA. They also demonstrate that the direct DNA sequence analysis can be automated, further simplifying the detection of new mutations at this locus. The mutations include DNA base substitutions, small DNA deletions, a single DNA base insertion, and errors in RNA splicing. The application of these procedures allows DNA diagnosis and carrier identification by the direct detection of the mutant alleles within individual families affected by LN.
Generalized linear models (GLMs), as defined by J. A. Nelder and R. W. M. Wedderburn (1972), unify a class of regression models for categorical, discrete, and continuous response variables. As an extension of classical linear models, GLMs provide a common body of theory and methodology for some seemingly unrelated models and procedures, such as the logistic, Poisson, and probit models, that are increasingly used in family studies. This article provides an overview of the principle and the key components of GLMs, such as the exponential family of distributions, the linear predictor, and the link function. To illustrate the application of GLMs, this article uses Canadian national survey data to build an example focusing on the number of close friends among older adults. The article concludes with a discussion of the strengths and weaknesses of GLMs.
Abstract To investigate the link between the functionality and the diversity of microbial communities under strong selective pressure from pollutants, two types of mesocosms that simulate natural attenuation and phytoremediation were generated using soil from a site highly contaminated with jet fuel and under air-sparging treatment. An increase in the petroleum hydrocarbon concentration from 4900 to 18-500-mg-kg-1-dw soil simulated a pollutant rebound (postremediation pollutant reversal due to residual contamination). Analysis of soil bacterial communities by denaturing gradient gel electrophoresis of PCR-amplified 16S rRNA gene fragments showed stronger changes and selection for a phylogenetically diverse microbial population in the mesocosms with pollutant-tolerant willow trees. Enumerat...
To gain in efficiency, lightness and volume, the hybrid and electric-powered cars will certainly follow the cellular phone path. The key of success of todays hybrid cars is the Ni-MH battery developed by Matsushita (87.5% of the market in 2004). The lithium-ion batteries will be the next step and would allow to supply 80 to 100% of the energy of the vehicle, the thermal engine becoming just an auxiliary system for additional power, autonomy and air-conditioning. Prototypes can reach today 200 to 450 km of autonomy and 130 km/h speeds with batteries of about 200 kg. If most of the safety problems linked with the Li technology have been solved, the main drawback remains the cost of the Li-ion technology. Short paper. (J.S.)
Smooth and notched specimens of the bearing steel 100Cr6 (SAE 52100) in a bainitic condition were used to determine the S-N curves under tensile, torsional and combined in- and out-of-phase loading. In the area of high-cycle fatigue, crack initiation was most likely caused by inclusions like Titanium Carbon nitrides or Aluminium Oxides. A micro mechanical model for the crack initiation by inclusions was developed. Another model was developed to describe the influence of these inclusions on the lifetime. A weakest-link model, using the statistical distribution of inclusions and surface flaws, was used to describe the endurance limit. (orig.)
In both office and home environments, Ethernet represents the dominant networking technology in use. Ethernet is low cost and the networks are fairly understood by users. The author began by explaining the physical and data link layers of Ethernet, then touched on fibre-optic cables. The industrial protocols were discussed, followed by Ethernet network topology. The environmental robustness of Ethernet networks was reviewed, with a word of caution from the author, advising to properly evaluate whether Ethernet represents a mission-critical component of the substation, as substation control houses are not environmentally controlled spaces, often minimally heated and no cooling. Engineering access to station Integrated Electric Drives (IEDs). By properly connecting Ethernet networks, it is possible to access relays in the substations from desktop engineering workstations in the central office. Network security issues must be addressed to prevent unauthorized access ...
Concerns are sometimes expressed about an alleged link between exposure to the extremely low frequency electromagnetic fields occurring in proximity to electricity networks or equipment. Transmission lines are specifically mentioned. The underlying physical mechanisms are described by which electric and magnetic fields exist, with particular reference to high voltage transmission lines. Epidemiological and laboratory studies are the two approaches used in research into the subject and the shortcomings inherent in many such studies and the inconsistencies in the results are mentioned. Some of the more recent epidemiological studies are referred to, also the possible interaction mechanisms between fields and the human body. The work of certain international and national bodies which were established to review the results of research into the alleged association between electromagnetic fields and ill-health are reported. (R.P.)
This article reports on the UN Environment Programme's (UNEP's) work in supporting the banking and financing sector by creating clean energy finance markets in developing countries. Details are given of the shifting of cash markets to credit, financing solar home systems in India, solar thermal lending in Tunisia, the financing of hotel based solar water heating in Morocco, and the Green Village Credit initiatives in the Yunnan province of China. The importance of providing banks with information needed to gain awareness and experience of renewable energy systems is stressed. The fundamentals of a bank engagement programme, financial catalysts, structuring market oriented approaches, and linking bank lending to policy making are discussed along with the need to shift to credit enhancements to help banks set up their first loan portfolios.
In the first paper of this series a formal theory of atomic scattering of electrons in the presence of an intense electromagnetic field was given. Cross sections, near the forward direction, between atomic states (modified by the laser) were obtained. However, it was assumed that the atom could not emit spontaneous radiation. In this paper the effect of spontaneous radiation is included, and it is shown that in most cases the measured cross section will be a weighted average of the two different cross sections starting from the two different initial states which are those atomic states resonantly linked by the laser. The Born approximation for the scattering is obtained, and it is shown that for the simplest description of the spontaneous radiation field the effect of the laser on the cross sections is simply to multiply them by a factor which depends upon the laser detuning. (AIP)
This study evaluated the clinical efficacy of treatment with oral risedronate (17.5?mg once daily) for 8?weeks in 11 Japanese patients with Paget?s disease of bone (PDB). Risedronate suppressed the excessive bone turnover associated with PDB and improved several biochemical markers, including serum alkaline phosphatase (ALP), serum bone-specific ALP (BALP), urinary deoxypyridinoline (DPD), and urinary cross-linked N-telopeptide of type 1 collagen (NTX). These markers began to decrease within about 2?weeks after the initiation of treatment in most patients, and the response persisted for up to 40?weeks after the cessation of treatment. Risedronate reduced pain by week 24 in most patients. According to quantitative bone scintigraphy, the lesion with the highest radioisotope (RI) uptake showe...
Abstract The glycosylation profile of therapeutic antibodies is routinely analyzed throughout development to monitor the impact of process parameters and to ensure consistency, efficacy, and safety for clinical and commercial batches of therapeutic products. In this study, unusually high levels of the mannose-5 (Man5) glycoform were observed during the early development of a therapeutic antibody produced from a Chinese hamster ovary (CHO) cell line, model cell line A. Follow up studies indicated that the antibody Man5 level was increased throughout the course of cell culture production as a result of increasing cell culture medium osmolality levels and extending culture duration. With model cell line A, Man5 glycosylation increased more than twofold from 12% to 28% in the fed-batch process...
The major contents in this study are as follows : - long-term forecast to the year of 2040 is provided for nuclear electricity generating capacity by means of logistic curve fitting method. - the role of nuclear power in a national economy is analyzed in terms of environmental regulation. To do so, energy-economy linked model is developed. By using this model, the benefits from the introduction of nuclear power in Korea are estimated. Study on inter-industry economic activity for nuclear industry is carried out by means of an input-output analysis. Nuclear industry is examined in terms of inducement effect of production, of value-added, and of import. - economic analysis of nuclear power generation is performed especially taking into consideration wide variations of foreign currency exchange rate. The result is expressed in levelized generating costs. (author). 27 refs., 24 tabs., 44 figs
Background Little is known about the role of diet in the development of venous thromboembolism (VTE). We explored the prospective relation of dietary patterns, food groups, and nutrients to incident VTE in older women. Methods In 1986, Iowa women aged 55 to 69 years completed a mailed survey, including a 127-item food frequency questionnaire. These data were linked to Medicare data from 1986 to 2004, and International Classification of Diseases discharge codes were used to identify hospitalized VTE cases. Cox regression analyses evaluated relations of 2 principal components?derived dietary patterns, 11 food groups, and 6 nutrients to VTE, adjusted for age, education, smoking status, physical activity, and energy intake. Results Over 19 years of follow-up, 1,950 of the 37,393 women develope...
This article presents the micro-electro-mechanical systems (MEMS) microrobot which demonstrates locomotion controlled by hardware neural networks (HNN). The size of the microrobot fabricated by the MEMS technology is 4 ? 4 ? 3.5 mm. The frame of the robot is made of silicon wafer, and it is equipped with a rotary-type actuator, a link mechanism, and six legs. The rotary-type actuator generates rotational movement by applying an electrical current to artificial muscle wires. The locomotion of the microrobot is obtained by the rotation of the rotary-type actuator. As in a living organism, the HNN realized robot control without using any software programs, A/D converters, or additional driving circuits. A central pattern generator (CPG) model was implemented as an HNN system to emulate the lo...
XMRV or xenotropic murine leukemia virus-related retrovirus, a recently discovered retrovirus, has been linked to both prostate cancer and chronic fatigue syndrome (CFS). Recently, the teams of Drs. Shyh-Ching Lo and Harvey Alter discovered the presence of sequences closely related to XMRV in the blood of 86.5% of patients with CFS [1]. These findings are important because since the initial discovery of XMRV in CFS, several studies have failed to find XMRV in specimens collected from CFS patients. While the current study also did not find XMRV in CFS, Lo et al. did detect sequences that belong to polytropic mouse endogenous retroviruses (PMV), which share considerable similarity with XMRV. Criteria for future studies that will help bring greater clarity to the issue of retroviral sequences in CFS are proposed below. PMID:21994623
The analysis of transmission line faults is essential to the proper performance of the power system. It is required if protective relays are to take the appropriate action and in monitoring the performance of relays, circuit breakers, and other protective and control elements. The detection and classification of transmission line faults is a fundamental component of such fault analysis. Another application of fault analysis is in software packages for automated analysis of digital fault recorder (DFR) files. Recently, such a package, called DFR Assistant, was developed for substation applications. This program can be installed locally in a substation, in which case it is connected directly to the DFR via a high speed parallel link, or it can be installed at a central station, in which case it can be configured to automatically analyze events coming from all DFRs.
A survey is given by the authors of methods of removing the sulphur dioxide content of fumes which can be linked together with producing useful final products. From these technologies those suppling well utilizable gypsum, the Walther process, producing ammonium sulphate, the Wellman-Lord and Bergbau-Forschung processes, respectively adapted to produce sulphuric acid or sulphur, may be of interest. Also in the method of fumes desulphurisation by catalysis by manganese, developed in KBFI, utilizable final products are given. Background of the work of developing this method. Detailed description of the manganese catalytic method based on the use of a red mud desulphurizing agent. By this process, in addition to desulphurizing fumes, enriched red mud with reduced Na/sub 2/O content is produced, which as an iron carrier, is to be reckoned with, or to be used in the cement industry for replacing imported calcined pyrites.
Some models anticipate that liberalized agricultural trade will lead to increased crop diversity, while other models make the opposite claim. These positions were explored in southwestern British Columbia, Canada where, between 1992 and 1998, government subsidies and other measures designed to protect horticultural farmers were lifted, exposing these farmers to foreign competition. Public hearings on the future of agriculture provided an opportunity to tap the knowledge and experience of people affected by this transition. Analysis of transcripts from these hearings, which was confirmed by industry data, shows that trade liberalization has led to the loss of the local fruit and vegetable processing industry. Stakeholders saw the loss as a major factor affecting the choice of crops grown lo...
Explicitly defining virtual collections in a digital library can benefit both users and contributors. This paper outlines the costs and benefits for defining virtual collections and describes an implementation of collection-level metadata in two digital libraries. Our work suggests that component repositories of NSDL would profit by describing their collection, and sub-collections, using a schema such as the one we implemented. This would enable NSDL to provide a rich, cross-linked hierarchy of virtual collections. By sharing collection-level, rather than item-level, metadata, collections would provide detailed resource information, presumably keeping most of their viewership, while NSDL would provide a broad description of resources.
The relativistic time dilation is reviewed in a cosmological context. We show that a clock or twin paradox does not arise if cosmic time is properly taken into account. The receding galaxy background provides a unique frame of reference, and the proper times of geodesic as well as accelerated observers can be linked to the universal cosmic time parameter. This suggests to compare the proper time differentials of the respective observers by determining their state of motion in the galaxy grid. In this way, each observer can figure out whether his proper time is dilated or contracted relative to any other. In particular one can come to unambiguous conclusions on the aging of uniformly moving observers, without reference to asymmetries in measurement procedures or accelerations they may have undergone.
Summation Copper-64 (T1/2?=?12.7 hours; ?+, 0.653?MeV [17.8 %]; ??, 0.579?MeV [38.4 %]) has decay characteristics that allow for positron emission tomography (PET) imaging and targeted radiotherapy of cancer. The well-established coordination chemistry of copper allows for its reaction with a wide variety of chelator systems that can potentially be linked to peptides and other biologically relevant small molecules, antibodies, proteins, and nanoparticles. The 12.7-hours half-life of 64Cu provides the flexibility to image both smaller molecules and larger, slower clearing proteins and nanoparticles. In a practical sense, the radionuclide or the 64Cu-radiopharmaceuticals can be easily shipped for PET imaging studies at sites remote to the production facility. Due to the versatility of 64Cu, ...
This article reports research findings related to converging formats, media, practices, and ideas in the process of academics' interaction with electronic texts during a research project. The findings are part of the results of a study that explored interactions of scholars in literary and historical studies with electronic texts as primary materials. Electronic texts were perceived by the study participants as fluid entities because the electronic environment promotes seamless interactions with a variety of media and formats. Working with electronic texts combines some traditional information and research practices into new patterns of information behavior. The practice called "netchaining" combines aspects of networking with information-seeking practices to establish and shape online information chains, which link sources and people. Different forms of exploration of participants' research questions were enabled by interactions with electronic texts.
A consideration is given to the problem of selecting optimized methods of radionuclide radiation registration during the control of the objects with essential changes in thickness. Adequate model of information signal formation is developed and analyzed for the case of the existence of an inertial link of the system with the dead time of a noncontinued type. The boundary values of radiation thickness and radiation flux intensity that divide the priority of using either digital or analog registration modes are revealed. The method is found for the full correction of a systematic error of flux intensity measurement because of the dead time of the apparatus. To control the objects with essential variation of thickness the method of selective measurement of radiation intensity is proposed
The earthworm gut provides ideal in situ conditions for ingested heterotrophic soil bacteria capable of anaerobiosis. High amounts of mucus- and plant-derived saccharides such as glucose are abundant in the earthworm alimentary canal, and high concentrations of molecular hydrogen (H2) and organic acids in the alimentary canal are indicative of ongoing fermentations. Thus, the central objective of this study was to resolve potential links between fermentations and active fermenters in gut content of the anecic earthworm Lumbricus terrestris by 16S ribosomal RNA (rRNA)-based stable isotope probing, with [13C]glucose as a model substrate. Glucose consumption in anoxic gut content microcosms was rapid and yielded soluble organic compounds (acetate, butyrate, formate, lactate, propionate, succi...
The study has analysed the effects of various factors on hydroelectric power generation potential to include climate change/variability, water demand, and installation of proposed hydroelectric power schemes in the Zambezi River Basin. An assessment of historical (1970?2000) power potential in relation to climate change/variability at existing hydro electric power schemes(Cahora Bassa, Kariba, Kafue Gorge and Itezhi-Tezhi) in the Zambezi River Basin was conducted. The correlation of hydroelectric power potential with climate change/variability aimed at observing the link and extent of influence of the latter on the former was investigated. In order to predict the future outlook of hydro electric power potential, General Circulation Models (GCM) were used to generate projected precipitation...
Maternal stress during pregnancy, particularly that combined with low socioeconomic status (SES), has been linked to an increased risk for impaired behavioural and emotional development and affective disorders in children. In animal models, acute periods of prenatal stress have profound effects on hypothalamo-pituitary-adrenal (HPA) function and behaviour. However, few studies have determined the impact of chronic exposure to stress in animal models. The objective of this study was to determine the effects of chronic maternal stress (CMS) during the 2nd half of pregnancy and nursing on growth, locomotor behaviour and HPA axis function in juvenile guinea pig offspring. Pregnant guinea pigs were exposed to a random combination of variable stressors every other day over the 2nd half of gestat...
The relationship between X chromosome-linked adrenoleukodystrophy and the red/green color pigment gene cluster on Xq28 was investigated in a large kindred. The DNA in a hemizygous male showed altered restriction fragment sizes compatible with at least a deletion extending from the 5[prime] end of the color pigment genes. Segregation analysis using a DNA probe within the color pigment gene cluster showed significant linkage with adrenoleukodystrophy (logarithm of odds score of 3.19 at [theta] = 0.0). These data demonstrate linkage, rather than association, between a unique molecular rearrangement in the color pigment gene cluster and adrenoleukodystrophy. The DNA changes in this region are thus likely to be helpful for determining the location and identity of the responsible gene. 33 refs., 4 figs.
Excessive physical activity plays an important role in the progression of anorexia nervosa (AN) by accelerating weight loss during dietary restriction. To search for mechanisms underlying this trait, a panel of mouse chromosome substitution strains derived from C57BL/6J and A/J strains was exposed to a scheduled feeding paradigm and to voluntary running wheel (RW) access. Here, we showed that A/J chromosomes 4, 12 and 13 contribute to the development of a disrupted RW activity in response to daily restricted feeding. This pattern is characterized by intense RW activity during the habitual rest phase and leads to accelerated body weight loss. Regions on mouse chromosomes 4, 12 and 13 display homology with regions on human chromosomes linked with anxiety and obsessionality in AN cohorts. The...
The concept of sustainable consumption (SC) has been proposed as a way of operationalising sustainable development (SD). However, until now, in view of the difficulties in conceptualising SC, emphasis has been placed mainly on a pragmatic approach. In an a-conceptual and pragmatic account of SC, many problems remain unaddressed, such as the danger of the notion becoming empty and lack of integration between the different dimensions of sustainability. In this paper, we propose that the informational space provided by the capability approach (CA) offers a conceptual framework to elaborate SC. The CA is employed here (i) to discuss the philosophical underpinnings of SC as part of a strategy for enhancing quality-of-life and (ii) to investigate the links between the different dimensions of SC....
Abstract A novel and convenient protocol for the preparation of an open-tubular column coated with chitosan-silica hybrid using chitosan and silane-coupling agent (-glycidoxy-propyltrimethoxysilane) was developed for CEC, in which, chitosan was covalently bonded to the inner wall of a fused-silica capillary using -glycidoxy-propyltrimethoxysilane as a cross-linking agent. The stationary phase was hydrophilic due to the chitosan-silica hybrid with abundant amine and hydroxyl functional groups. The chromatographic characteristics of the column were evaluated by the separation of some organic acids and inorganic anions. The column showed good selectivity for nucleotides, aromatic acids, and inorganic anions. The mechanism for the separation of these compounds was primarily based on the hydrop...
The use of dendrimers for preparing chemically sensitive interfaces for detecting volatile organic compounds (VOCs) using surface acoustic wave (SAW) device transducers is described. Specifically, the synthesis of the dendrimers and the means by which they are affixed to SAW devices is discussed, followed by a detailed spectroscopic analysis of the surface-confined dendrimers and a discussion of their interaction with different VOCs. Most of these preliminary experiments focus on dendrimer surface modification using benzoylchloride, which leads to phenyl terminal groups linked to the dendrimer via amide groups. The results of this study lead us to conclude that dendrimers: (1) provide general specificity towards classes of functional groups and are therefore suitable for array-based sensing schemes; (2) are intermediate in structure between monolayers and polymers and exhibit the desirable properties of both; (3) can be straightforwardly attached to the surfaces of ...
Course website from Cambridge on ceramic materials. This site contains eight lectures in PDF format (Adobe Reader required), two question sheets, five practicals (including answers), digital movies and further useful links. "There is a strong relationship between the structure of a material and its physical properties. The properties of a material whether mechanical, electrical, optical or magnetic, determine how it can be used in practical applications. In this course, the focus is on the structure / property relationship for ionic materials with electrical properties utilised in various transducer devices. The materials considered include perovskites, which have special polarisation properties exploited in ferroelectric, pyroelectric and piezoelectric devices. Other oxides, such as zirconia, have structures permitting rapid diffusion of ions, making them suitable for use in sensors, fuel cells and batteries. The scientific principles underlying the properties of ...
Purpose - The article discusses how care programmes and integrated care pathways can be linked, finding ways to improve healthcare process professional and logistical quality from a supply chain and a network point-of-view. Design/methodology/approach - The authors argue that owing to cost containment goals and increasing healthcare demand, healthcare services systems are challenged to improve service quality, whilst at the same time finding ways to improve delivery processes. It explores if the combination of two instruments, care programmes and integrated care pathways, can meet both goals. This combination is illustrated by an example from the Institute of Mental Health Care Eindhoven en de Kempen. Findings - Analysis suggests that care programmes can be combined with integrated care pa...
First generation biofuels provide a number of ecosystem services (e.g., fuel, climate regulation) but they also compromise other ecosystem services (e.g., food, freshwater services) which are of paramount value to human wellbeing. However, this knowledge is fragmented and little is known about how the ecosystem services provided and/or compromised by biofuels link to human wellbeing. In fact, whether biofuels production and use can have a negative or positive impact on the environment and society depends on several interconnected factors. This paper provides a critical review of the drivers, impacts and tradeoffs of biofuel production and use. In particular, it rationalizes the evidence coming from diverse academic disciplines and puts it into perspective by employing the ecosystem service...
Objectives1. To create a strong, interdisciplinary evidence base about the relationships linking ecosystems, agrobiodiversity, wild biodiversity, and sustainable livelihoods, including the use of trade-off analysis (modeling the relationships between agricultural productivity, levels of biodiversity, and ecosystem resilience); crop evolutionary studies (wild relative/crop interactions) and socioeconomic, cultural, and nutritional studies of the contribution of biodiversity to different livelihoods asset [continued...]DescriptionAgriculture, ecosystems, and humans have co-evolved over millennia in the Andean-Amazonian region, creating the richest of all Vavilov centers of crop origin and diversity. The conservation of a wide range of domesticated crops and landraces (i.e., indigenous, ancestral varieties or cultivars that are distinct, uniform, and stable) and their co-evolution with crop wild relatives (CRW) has been essential for food security, adaptation to ...
AbstractBACKGROUND: Disparities in treatment and mortality for colorectal cancer (CRC) may reflect differences in access to specialized care or other characteristics of the area where an individual lives. METHODS: Surveillance, Epidemiology and End Results Program-Medicare data for seniors diagnosed with CRC were linked to area measures of the sociodemographic characteristics and the capacity of surgeons, medical oncologists, and radiation oncologists. Outcomes included receipt of stage-appropriate CRC care and mortality. RESULTS: After adjustment, blacks and Hispanics were less likely than whites to undergo surgery (odds ratio [OR] 0.57, 95% confidence interval (CI) 0.52-0.63 and OR 0.82, 95% CI 0.70-0.95, respectively). Individuals who lived in areas with the highest tertile of surgeon c...
Application of the Geographic Information System (GIS) with a statistical model to evaluate the magnetic field exposure of a population from high-voltage transmission lines near residential areas is discussed, focusing on the interaction of the GIS with the statistical model. In an effort to validate the model measurements of the magnetic field, profiles were taken at two sites and these profiles have been compared with calculated values. Two conclusions have been drawn from the results: (1) the statistical model linked with the GIS is a very powerful tool for the evaluation of exposure of a population to magnetic fields, and (2) success depends on the presence of other sources of magnetic fields and on the exactness of the data used in the model. 4 refs., 5 figs.
Apelin is a peptide known as the ligand of the G-protein-coupled receptor APJ. Several active apelin forms exist such as apelin-36, apelin-17, apelin-13, and the pyroglutamated form of apelin-13. Apelin and APJ are expressed in the central nervous system, particularly in the hypothalamus and in many peripheral tissues. Apelin has been shown to be involved in the regulation of cardiovascular and fluid homeostasis, food intake, cell proliferation, and angiogenesis. In addition to be an ubiquitous peptide, apelin is also produced and secreted by adipocytes and thus considered as an adipokine. This has opened a new field of investigation establishing a link between apelin and metabolic disorders (obesity, type 2 diabetes, etc.) which is the focus of the present review. Several studies, but not...
A fully consistent linear perturbation theory for cosmology is derived in the presence of quantum corrections as they are suggested by properties of inverse volume operators in loop quantum gravity. The underlying constraints present a consistent deformation of the classical system, which shows that the discreteness in loop quantum gravity can be implemented in effective equations without spoiling space-time covariance. Nevertheless, non-trivial quantum corrections do arise in the constraint algebra. Since correction terms must appear in tightly controlled forms to avoid anomalies, detailed insights for the correct implementation of constraint operators can be gained. The procedures of this article thus provide a clear link between fundamental quantum gravity and phenomenology.
Methods were developed for the separation of radioactively labeled carbohydrate components of proteoglycans by isocratic ion-moderated partition HPLC. Neutral sugars were separated after hydrolysis in trifluoroacetic acid with baseline separation between glucose, xylose, galactose, fucose, and mannose. N-Acetylneuraminic acid, N-acetylated hexosamines, glucose, galactose, and xylitol were likewise well separated from each other under isocratic elution conditions. Glucuronic acid, iduronic acid, and their lactones were separated after hydrolysis in formic acid and sulfuric acid. Glucosamine, galactosamine, galactosaminitol, and glucosaminitol were separated by HPLC on a cation exchanger with neutral buffer after hydrolysis in hydrochloric acid. THe separation techniques also proved useful in fractionation of exoglycosidase digests of O- and N-linked oligosaccharides. Separations of aldoses, hexosamines, and uronic acids were adapted to sensitive photometric ...
Abstract Alcohol drinking is highly prevalent in many cultures and contributes to the global burden of disease. In fact, it was shown that alcohol constitutes 3.2% of all worldwide deaths in the year 2006 and is linked to more than 60 diseases, including cancers, cardiovascular diseases, liver cirrhosis, neuropsychiatric disorders, injuries and foetal alcohol syndrome. Alcoholism, which has been proven to have a high genetic load, is one potentially fatal consequence of chronic heavy alcohol consumption, and may be regarded as one of the most prevalent neuropsychiatric diseases afflicting our society today. The aim of the integrated genome research network -Genetics of Alcohol Addiction--which is a German inter-/trans-disciplinary life science consortium consisting of molecular biologists,...
Since Classical Antiquity numerous authors have linked the origin of some mental disorders to physical and functional changes in the pineal gland because of its attributed role in humans as the connection between the material and the spiritual world. The pineal organ was seen as a valve-like structure that regulated the flow of animal spirits through the ventricular system, a hypothesis that took on more vigour during the Middle Ages and the Renaissance. The framework for this theory was ''the three cells of the brain'', in which the pineal gland was even called the ''appendix of thought''. The pineal gland could also be associated with the boom, during this period, of certain legends about the ''stone of folly''. But the most relevant psychopathological role of this organ arrived with Des...
Linear-optical passive (LOP) devices and photon counters are sufficient to implement universal quantum computation with single photons, and particular schemes have already been proposed. In this paper we discuss the link between the algebraic structure of LOP transformations and quantum computing. We first show how to decompose the Fock space of N optical modes in finite-dimensional subspaces that are suitable for encoding strings of qubits and invariant under LOP transformations (these subspaces are related to the spaces of irreducible unitary representations of U (N). Next we show how to design in algorithmic fashion LOP circuits which implement any quantum circuit deterministically. We also present some simple examples, such as the circuits implementing a cNOT gate and a Bell state generator/analyser.
Many species of entomophagous arthropods have been introduced either intentionally (through the practice of biological control) or unintentionally to new regions. We examine interactions of these aliens with their new environments in the context of rapid global change linked to human activity. We consider effects of such interactions on establishment and spread of the alien species and effects on indigenous biota and ecosystems. Major elements of global change that affect alien-environment interactions include landscape modifications by humans (e.g., cultivation, habitat loss and fragmentation) and increases in atmospheric CO2 and other gases resulting in climate change and other effects (e.g., changes in food quality for herbivores that affect higher trophic levels as well). Alien arthrop...
A novel algebraic topology approach to supersymmetry (SUSY) and symmetry breaking in quantum field and quantum gravity theories is presented with a view to developing a wide range of physical applications. These include: controlled nuclear fusion and other nuclear reaction studies in quantum chromodynamics, nonlinear physics at high energy densities, dynamic Jahn-Teller effects, superfluidity, high temperature superconductors, multiple scattering by molecular systems, molecular or atomic paracrystal structures, nanomaterials, ferromagnetism in glassy materials, spin glasses, quantum phase transitions and supergravity. This approach requires a unified conceptual framework that utilizes extended symmetries and quantum groupoid, algebroid and functorial representations of non-Abelian higher dimensional structures pertinent to quantized spacetime topology and state space geometry of quantum operator algebras. Fourier transforms, generalized Fourier-Stieltjes transforms, and duality ...
VHF wind-profiling radars often measure a decrease of echo power with zenith angle, which can be explained from in situ measurements of horizontal layering or anisotropy of metre-scale temperature structure in the atmosphere. There can also be an azimuthal variation of echo power, which is increased in an azimuth opposite to the vertical shear vector of horizontal wind. This paper checks if the azimuth variation can also be linked to in situ observations of temperature structure, using aircraft flights in the tropopause region near a VHF radar. At heights where VHF radar measures wind shear and aspect sensitivity, there can be an asymmetry in the probability distribution of horizontal gradient of potential temperature, for horizontal scale of e.g. hundreds of metres. The asymmetry is often...
Industrial premises bear more and more important thermal constraints which can commonly reach 150 W/m{sup 2} and more. The reason is the general development of automation and automatic devices and the better thermal insulation of buildings. Production quality requires also more and more strict ambient conditions (temperature, humidity, air quality, air flow etc..). Thus, the air-conditioning market in the industrial sector is more linked to economic factors such as productivity and profit than to thermal comfort of workers. However, the air-conditioning potentialities in the industrial sector remains under-exploited in France. This paper analyzes the reasons of this situation in terms of investments and equipments. (J.S.)
We have conducted an agent-based simulation of chain bankruptcy. The propagation of credit risk on a network, i.e., chain bankruptcy, is the key to nderstanding largesized bankruptcies. In our model, decrease of revenue by the loss of accounts payable is modeled by an interaction term, and bankruptcy is defined as a capital deficit. Model parameters were estimated using financial data for 1,077 listed Japanese firms. Simulations of chain bankruptcy on the real transaction network consisting of those 1,077 firms were made with the estimated model parameters. Given an initial bankrupt firm, a list of chain bankrupt firms was obtained. This model can be used to detect high-risk links in a transaction network, for the management of chain bankruptcy.
A theoretical framework for the hierarchical multiscale modeling of inelastic response of heterogeneous materials has been presented. Within this multiscale framework, the second gradient is used as a non local kinematic link between the response of a material point at the coarse scale and the response of a neighborhood of material points at the fine scale. Kinematic consistency between these scales results in specific requirements for constraints on the fluctuation field. The wryness tensor serves as a second-order measure of strain. The nature of the second-order strain induces anti-symmetry in the first order stress at the coarse scale. The multiscale ISV constitutive theory is couched in the coarse scale intermediate configuration, from which an important new concept in scale transitions emerges, namely scale invariance of dissipation. Finally, a strategy for developing meaningful kinematic ISVs and the proper free energy functions and evolution kinetics is ...
Suppose an astronomer is equipped with a device capable of detecting emissions -- whether they be electromagnetic, gravitational, or neutrino -- from transient sources distributed throughout the cosmos. Because of source rate density evolution and variation of cosmological volume elements, the sources first detected when the machine is switched on are likely to be ones in the high-redshift universe; as observation time increases, rarer, more local, events will be found. We characterize the observer's evolving record of events in terms of a "probability event horizon", converging on the observer from great distances at enormous speed, and illustrate it by simulating neutron star birth events distributed throughout the cosmos. As an initial application of the concept, we determine the approach of this horizon for gamma-ray bursts (GRBs) by fitting to redshift data. The event rates required to fit the model are consistent with the proposed link between core-collapse ...