Revaluation to activation activity of reactor evaluated at the notification of dismantling submitted in 1997 was carried out in JRR-2 where decommissioning was advanced now. In the revaluation, estimation accuracy on neutron streaming at various horizontal experimental tubes was improved by applying 3 dimensional model to neutron transport calculation that had been carried out by 2 dimensional model, and calculating with TORT. As the result, excessive overestimations on horizontal experimental tubes and biological shield that had greatly contributed to total activation activity in evaluation at the notification of dismantling was revised, sum of their activation activities in the revaluation decreased to 1/18 (case after 1 year from the permanent shutdown of reactor) of evaluation at the notification of dismantling, and the structural materials that had large activation activity were changed. By the above, it was shown that introducing 3 dimensional model was effective in evaluation on activation activity of the research reactor that had a lot of various experimental tubes. Total activation activity of reactor by the revaluation depended on control rods, thermal shield plates and horizontal experimental tubes, and the value after 1 year from the permanent shutdown of reactor was 1.9x1014 Bq. (author)
Vitruk, S.G.; Korsun, A.S. [Moscow Engineering Physics Institute (Russian Federation); Ushakov, P.A. [Institute of Physics and Power Engineering, Obninsk (R)] [and others
1995-09-01
The multilevel mathematical model of neutron thermal hydrodynamic processes in a passive safety core without assemblies duct walls and appropriate computer code SKETCH, consisted of thermal hydrodynamic module THEHYCO-3DT and neutron one, are described. A new effective discretization technique for energy, momentum and mass conservation equations is applied in hexagonal - z geometry. The model adequacy and applicability are presented. The results of the calculations show that the model and the computer code could be used in conceptual design of advanced reactors.
A 3-dimensional calculation model of the Danish research reactor DR3 has been developed. Demands of a more effective utilization of the reactor and its facilities has required a more detailed calculation tool than applied so far. A great deal of attention has been devoted to the treatment of the coarse control arms. The model has been tested against measurements with satisfying results. Furthermore the model has been used to analyse a proposal to a new core design called ring-core where 4 central fuel elements are replaced by 4 dummy elements to increase the thermal flux in the center of the reactor. (author)
For the analysis of transient and emergency processes during reactor operation it is necessary to have a set of codes, which calculate physical processes with a various degree of accuracy. Codes CORT and BUMT for three-dimensional thermohydraulic calculation of fast reactor core in steady state, transient and accident conditions are described in this paper. The code CORT calculates thermohydraulics of the whole fast reactor core or group of subassemblies in simplified approximation. The core is described as a set of coupled one-dimensional channels or is divided into a set of ring zones, each of those is also represented by one subassembly (S/A). The detailed three-dimensional calculation of particular S/A is carried out by code BUMT. For description of S/A thermohydraulics the authors have chosen so called 'subchannel model. In this model the S/A is split into number of channels exchanging one by one with mass, momentum and energy. The coefficients of inter channel exchange are calculated on the basis of empirical correlations. The subchannel model is supplemented by detailed (two-dimensional in each axial cross-section) calculation of fuel pin and S/A wrapper temperatures. For solution of hydrodynamic equations the full-implicit scheme is used. Code BUMT was verified using experimental data for S/A-simulators and results of calculations obtained by other codes. These codes when used in complex with neutronic code and first circuit thermohydraulic code could describe in detail the thermal state of coolant and performance of fuel pins and construction elements of reactor during steady and transient states of its operation. (author)
In the frame of a project on scientific-technical co-operation funded by BMBF/BMWi, the program code DYN3D and the coupled code ATHLET-DYN3D have been transferred to the Institute for Nuclear Research and Nuclear Energy (INRNE) Sofia. The coupled code represents an implementation of the 3D core model DYN3D developed by FZR into the GRS thermal-hydraulics code system ATHLET. For the purpose of validation of these codes, a measurement data base about a start-up experiment obtained at the unit 6 of Kozloduy NPP (VVER-1000/V-320) has been generated. The results of performed validation calculations were compared with measurement values from the data base. A simplified model for estimation of cross flow mixing between fuel assemblies has been implemented into the program code DYN3D by Bulgarian experts. Using this cross flow model, transient processes with asymmetrical boundary conditions can be analysed more realistic. The validation of the implemented model were performed with help of comparison calculations between modified DYD3D code and thermal-hydraulics code COBRA-4I, and also on the base of the collected measurement data from Kozloduy NPP. (orig.)
3 - Dimensional Body Measurement Technology
ZHOU Xu-dong; LI Yan-mei
2002-01-01
3 - dimensional body measurement technology, the basis of developing high technology in industry, accelerates digital development of aplparel industry. This paper briefly introduces the history of 3 - dimensional body measurement technology, and recounts the principle and primary structure of some types of 3 - dimensional automatic body measurement system. With this understanding, it discusses prospect of 3- dimensional CAD and virtual technology used in apparel industry.
Ultrahigh Resolution 3-Dimensional Imaging Project
National Aeronautics and Space Administration — Southwest Sciences proposes to develop innovative instrumentation for the rapid, 3-dimensional imaging of biological tissues with cellular resolution. Our approach...
3-dimensional polymer gel dosimetry
Recently developed techniques in conformal radiotherapy demand special properties of radiation dosimeters. Polymer gel dosimeter evaluated by nuclear magnetic resonance (NMR) is promising tool which can be used for measuring rather complicated 3-dimensional dose distributions with required precision of ± 5 %. This system is based on radiation-induced polymerisation and cross-linking of acrylic monomers which are uniformly dispersed in aqueous gel. The formation of cross-linked polymers in the irradiated regions of the gel increases the NMR relaxation rates of neighbouring water protons. BANG-2 type polymer gel was prepared. The composition of gel dosimeter was as follows: 3 % N,N'-methylene-bisacrylamide, 3 % acrylic acid, 1 % sodium hydroxide, 5 % gelatine, and 88 % water, where all percentages are by weight. The dosimeters in glass vessels were homogeneously irradiated by 60Co gamma photons in a Gammacell 220 unit and by 4 MV, 6 MV and 18 MV X ray photons on Varian Clinac 600C and 2100 C linear accelerators by doses in the range of 0-50 Gy. Evaluation of dosimeters was performed on Siemens EXPERT 1 T and Siemens VISION 1,5 T scanners. Multi-echo CPMG sequence with 16 echoes was used for the evaluation of T2-relaxation times in irradiated gel dosimeters. The dependence of 1/T2 response of dosimeters was studied on following factors: absorbed dose, energy of applied radiation, temperature during NMR evaluation, time since irradiation to NMR evaluation and strength of the magnetic field. An exponential dependence of 1/T2 response on absorbed dose in the range of 0-50 Gy was observed, in the range 0-10 Gy the data could be fitted by a linear function. There was observed no dependence of 1/T2 response on: energy (for three different photon energies used in this study), strength of magnetic field of NMR scanner, time from irradiation of the dosimeters to NMR evaluation. Increase of gel dosimeter 1/T2 response with the decrease of the temperature during NMR evaluation
Teleportation of a 3-dimensional GHZ State
Cao, Hai-Jing; Wang, Huai-Sheng; Li, Peng-Fei; Song, He-Shan
2012-05-01
The process of teleportation of a completely unknown 3-dimensional GHZ state is considered. Three maximally entangled 3-dimensional Bell states function as quantum channel in the scheme. This teleportation scheme can be directly generalized to teleport an unknown d-dimensional GHZ state.
3-dimensional Griess algebras and Miyamoto involutions
lam, Ching Hung; Yamauchi, Hiroshi
2016-01-01
We consider a series of VOAs generated by 3-dimensional Griess algebras. We will show that these VOAs can be characterized by their 3-dimensional Griess algebras and their structures are uniquely determined. As an application, we will determine the groups generated by the Miyamoto involutions associated to Virasoro vectors of our VOAs.
3-dimensional Oil Drift Simulations
Wettre, C.; Reistad, M.; Hjøllo, B.Å.
Simulation of oil drift has been an ongoing activity at the Norwegian Meteorological Institute since the 1970's. The Marine Forecasting Centre provides a 24-hour service for the Norwegian Pollution Control Authority and the oil companies operating in the Norwegian sector. The response time is 30 minutes. From 2002 the service is extended to simulation of oil drift from oil spills in deep water, using the DeepBlow model developed by SINTEF Applied Chemistry. The oil drift model can be applied both for instantaneous and continuous releases. The changes in the mass of oil and emulsion as a result of evaporation and emulsion are computed. For oil spill at deep water, hydrate formation and gas dissolution are taken into account. The properties of the oil depend on the oil type, and in the present version 64 different types of oil can be simulated. For accurate oil drift simulations it is important to have the best possible data on the atmospheric and oceanic conditions. The oil drift simulations at the Norwegian Meteorological Institute are always based on the most updated data from numerical models of the atmosphere and the ocean. The drift of the surface oil is computed from the vectorial sum of the surface current from the ocean model and the wave induced Stokes drift computed from wave energy spectra from the wave prediction model. In the new model the current distribution with depth is taken into account when calculating the drift of the dispersed oil droplets. Salinity and temperature profiles from the ocean model are needed in the DeepBlow model. The result of the oil drift simulations can be plotted on sea charts used for navigation, either as trajectory plots or particle plots showing the situation at a given time. The results can also be sent as data files to be included in the user's own GIS system.
The 3-Dimensional Core Model DYN3D
Mittag, Siegfried; Rohde, Ulrich; Grundmann, Ulrich
2010-01-01
Analyzing the safety margins in transients and accidents of nuclear reactors 3-dimensional models of the core were used to avoid conservative assumptions needed for point kinetics or 1-dimensional models. Therefore the 3D code DYN3D has been developed for the analysis of reactivity initiated accidents (RIA) in thermal nuclear reactors. The power distributions are calculated with the help of nodal expansion methods (NEM) for hexagonal and Cartesian geometry. The fuel rod model and the thermohy...
Decay vertex reconstruction and 3-dimensional lifetime determination at BESⅢ
XU Min; HE Kang-Lin; ZHANG Zi-Ping; WANG Yi-Fang; BIAN Jian-Ming; CAO Guo-Fu; CAO Xue-Xiang; CHEN Shen-Jian; DENG Zi-Yan; FU Cheng-Dong; GAO Yuan-Ning; HAN Lei; NAN Shao-Qing; HE Miao; HU Ji-Feng; HU Xiao-Wei; HUANG Bin; HUANG Xing-Tao; JIA Lu-Kui; JI Xiao-Sin; LI Hai-Bo; LI Wei-Dong; LIANG Yu-Wie; LIU Chun-Xiu; LIU Huai-Min; LIU Ying; LIU Yong; LUO Tao; L(U) Qi-Wen; MA Qiu-Mei; MA Xiang; MAO Ya-Jun; MAO Ze-Pu; MO Xiao-Hu; NING Fei-Peng; PING Rong-Gang; QIU Jin-Fa; SONG Wen-Bo; SUN Sheng-Sen; SUN Xiao-Dong; SUN Yong-Zhao; TIAN Hao-Lai; WANG Ji-Ke; WANG Liang-Liang; WEN Shuo-Pin; WU Ling-Hui; WU Zhi; XIE Yu-Guang; YAN Jie; YAN Liang; YAO Jian; YUAN Chang-Zheng; YUAN Ye; ZHANG Chang-Chun; ZHANG Jian-Yong; ZHANG Lei; ZHANG Xue-Yao; ZHANG Yao; ZHENG Yang-Heng; ZHU Yong-Sheng; ZOU Jia-Heng
2009-01-01
This paper focuses mainly on the vertex reconstruction of resonance particles with a relatively long lifetime such as KSO, A, as well as on lifetime measurements using a 3-dimensional fit. The kinematic constraints between the production and decay vertices and the decay vertex fitting algorithm based on the least squares method are both presented. Reconstruction efficiencies including experimental resolutions are discussed. The results and systematic errors are calculated based on a Monte Carlo simulation.
Properties of 3-dimensional line location models
Brimberg, Jack; Juel, Henrik; Schöbel, Anita
2002-01-01
We consider the problem of locating a line with respect to some existing facilities in 3-dimensional space, such that the sum of weighted distances between the line and the facilities is minimized. Measuring distance using the l\\_p norm is discussed, along with the special cases of Euclidean and...
Homological aperiodic tilings of 3-dimensional geometries
Nowak, Piotr W
2012-01-01
We construct the first aperiodic tiles for two amenable 3-dimensional Lie groups: Sol and the Heisenberg group. Our construction relies on the use of higher-dimensional uniformly finite homology. In particular, we settle completely the existence of aperiodic tiles for all of the non-compact geometries of 3-manifolds appearing in the geometrization conjecture.
3-dimensional shaped aluminium foam sandwiches
Baumeister, J. [Fraunhofer-Institut fuer Fertigungstechnik und Angewandte Materialforschung, Bremen (Germany); Baumgaertner, F. [Schunk Sintermetalltechnik, Giessen (Germany); Gers, H. [Honsel AG, Meschede (Germany); Seeliger, W. [Wilhelm Karmann GmbH, Osnabrueck (Germany)
2000-07-01
3-dimensional shaped sandwich panels with a very high stiffness can be produced in an elegant way by combining aluminium face sheets with an aluminium foam core. For this, a mixture of aluminium powder and a foaming agent is compressed to a semi-finished product of nearly vanishing porosity by extrusion, powder rolling or hot isostatic pressing. The resulting foamable semi-finished aluminium material is roll clad with sheets of conventional sheet or aluminium. As a result a precursor material is obtained consisting of two face sheets which are metallurgically bonded to the foamable core layer. This sandwich precursor material can be shaped into a 3-dimensional part by conventional techniques, e.g. by stamping or deep drawing. In a final step the foamable precursor material is heated up to the melting point of the core layer thus initiating its expansion into the desired 3-dimensional shaped sandwich structure. The porosity of the foamed core layer is in the range from 80-90% so that the integral density of the sandwich structure can be as low as 0,7 g/cm{sup 3}. The sandwich materials combine the low weight and high bending stiffness with the advantages of the face sheets, i.e. the high strength and weldability. The manufacturing process will be described in detail and the material properties will be shown. Current and future possible applications will be outlined as well as concrete parts produced up to date. (orig.)
A New Approach to 3-Dimensional Fields
agashe, sadanand
2016-01-01
A new approach, using the operator "x d/dx + y d/dy + z d/dz", is introduced for studying 3-dimensional scalar and vector fields. The approach uses a property of the operator which is similar to that of the Laplacian operator, but the operator does not seem to have been used before. Also, the operator requires only once-differentiability of the fields. Using it, a number of new formulas are derived and new proofs given for many classical results such as the Helmholtz theorem, the Poisson form...
3-dimensional defect TQFTs and their tricategories
Carqueville, Nils; Schaumann, Gregor
2016-01-01
We initiate a systematic study of 3-dimensional `defect' topological quantum field theories, that we introduce as symmetric monoidal functors on stratified and decorated bordisms. For every such functor we construct a tricategory with duals, which is the natural categorification of a pivotal bicategory. This captures the algebraic essence of defect TQFTs, and it gives precise meaning to the fusion of line and surface defects as well as their duality operations. As examples, we discuss how Reshetikhin-Turaev and Turaev-Viro theories embed into our framework, and how they can be extended to defect TQFTs.
The 3-dimensional Einstein-Klein-Gordon system in characteristic numerical relativity
Barreto, W.; Da Silva, A.; Gomez, R.; Lehner, L.; Rosales, L.; Winicour, J.
2005-01-01
We incorporate a massless scalar field into a 3-dimensional code for the characteristic evolution of the gravitational field. The extended 3-dimensional code for the Einstein--Klein--Gordon system is calibrated to be second order convergent. It provides an accurate calculation of the gravitational and scalar radiation at infinity. As an application, we simulate the fully nonlinear evolution of an asymmetric scalar pulse of ingoing radiation propagating toward an interior Schwarzschild black h...
3-dimensional bioprinting for tissue engineering applications.
Gu, Bon Kang; Choi, Dong Jin; Park, Sang Jun; Kim, Min Sup; Kang, Chang Mo; Kim, Chun-Ho
2016-01-01
The 3-dimensional (3D) printing technologies, referred to as additive manufacturing (AM) or rapid prototyping (RP), have acquired reputation over the past few years for art, architectural modeling, lightweight machines, and tissue engineering applications. Among these applications, tissue engineering field using 3D printing has attracted the attention from many researchers. 3D bioprinting has an advantage in the manufacture of a scaffold for tissue engineering applications, because of rapid-fabrication, high-precision, and customized-production, etc. In this review, we will introduce the principles and the current state of the 3D bioprinting methods. Focusing on some of studies that are being current application for biomedical and tissue engineering fields using printed 3D scaffolds. PMID:27114828
A dilogarithmic 3-dimensional Ising tetrahedron
Broadhurst, D J
1999-01-01
In 3 dimensions, the Ising model is in the same universality class as unknown analytical nature. In contrast, all single-scale 4-dimensional tetrahedra were reduced, in hep-th/9803091, to special values of exponentially convergent polylogarithms. Combining dispersion relations with the integer-relation finder PSLQ, we find that $C^{Tet}/2^{5/2} = Cl_2(4\\alpha) - Cl_2(2\\alpha)$, with $Cl_2(\\theta):=\\sum_{n>0}\\sin(n\\theta)/n^2$ and 1,000-digit precision and readily yields 50,000 digits of $C^{Tet}$, after transformation to an exponentially convergent sum, akin to those studied in math.CA/9803067. It appears that this 3-dimensional result entails a polylogarithmic ladder beginning with the classical formula for $\\pi/\\sqrt2$, in the manner that 4-dimensional results build on that for $\\pi/\\sqrt3$.
Performance Analysis of 3-Dimensional Turbo Codes
Rosnes, Eirik
2011-01-01
In this work, we consider the minimum distance properties and convergence thresholds of 3-dimensional turbo codes (3D-TCs), recently introduced by Berrou et al.. Here, we consider binary 3D-TCs while the original work of Berrou et al. considered double-binary codes. In the first part of the paper, the minimum distance properties are analyzed from an ensemble perspective, both in the finite-length regime and in the asymptotic case of large block lengths. In particular, we analyze the asymptotic weight distribution of 3D-TCs and show numerically that their typical minimum distance dmin may, depending on the specific parameters, asymptotically grow linearly with the block length, i.e., the 3D-TC ensemble is asymptotically good for some parameters. In the second part of the paper, we derive some useful upper bounds on the dmin when using quadratic permutation polynomial (QPP) interleavers with a quadratic inverse. Furthermore, we give examples of interleaver lengths where an upper bound appears to be tight. The b...
Cardiothoracic Applications of 3-dimensional Printing.
Giannopoulos, Andreas A; Steigner, Michael L; George, Elizabeth; Barile, Maria; Hunsaker, Andetta R; Rybicki, Frank J; Mitsouras, Dimitris
2016-09-01
Medical 3-dimensional (3D) printing is emerging as a clinically relevant imaging tool in directing preoperative and intraoperative planning in many surgical specialties and will therefore likely lead to interdisciplinary collaboration between engineers, radiologists, and surgeons. Data from standard imaging modalities such as computed tomography, magnetic resonance imaging, echocardiography, and rotational angiography can be used to fabricate life-sized models of human anatomy and pathology, as well as patient-specific implants and surgical guides. Cardiovascular 3D-printed models can improve diagnosis and allow for advanced preoperative planning. The majority of applications reported involve congenital heart diseases and valvular and great vessels pathologies. Printed models are suitable for planning both surgical and minimally invasive procedures. Added value has been reported toward improving outcomes, minimizing perioperative risk, and developing new procedures such as transcatheter mitral valve replacements. Similarly, thoracic surgeons are using 3D printing to assess invasion of vital structures by tumors and to assist in diagnosis and treatment of upper and lower airway diseases. Anatomic models enable surgeons to assimilate information more quickly than image review, choose the optimal surgical approach, and achieve surgery in a shorter time. Patient-specific 3D-printed implants are beginning to appear and may have significant impact on cosmetic and life-saving procedures in the future. In summary, cardiothoracic 3D printing is rapidly evolving and may be a potential game-changer for surgeons. The imager who is equipped with the tools to apply this new imaging science to cardiothoracic care is thus ideally positioned to innovate in this new emerging imaging modality. PMID:27149367
3-dimensional analysis of FELIX brick with hole
Electromagnetic induction on FELIX brick with a hole has been analyzed with 3-Dimensional EDDYNET computer code. Incorporating loop currents on hexahedral meshes, the 3-Dimensional EDDYNET program solves eddy current problems by a network approach, and provides good accuracy even for coarse meshes. (author)
PWR core safety analysis with 3-dimensional methods
Highlights: • An overview of AREVA’s safety analysis codes their coupling is provided. • The validation base and licensing applications of these codes are summarized. • Coupled codes and methods provide improved margins and non-conservative results. • Examples for REA and inadvertent opening of the pressurizer safety valve are given. - Abstract: The main focus of safety analysis is to demonstrate the required safety level of the reactor core. Because of the demanding requirements, the quality of the safety analysis strongly affects the confidence in the operational safety of a reactor. To ensure the highest quality, it is essential that the methodology consists of appropriate analysis tools, an extensive validation base, and last but not least highly educated engineers applying the methodology. The sophisticated 3-dimensional core models applied by AREVA ensure that all physical effects relevant for safety are treated and the results are reliable and conservative. Presently AREVA employs SCIENCE, CASMO/NEMO and CASCADE-3D for pressurized water reactors. These codes are currently being consolidated into the next generation 3D code system ARCADIA®. AREVA continuously extends the validation base, including measurement campaigns in test facilities and comparisons of the predictions of steady state and transient measured data gathered from plants during many years of operation. Thus, the core models provide reliable and comprehensive results for a wide range of applications. For the application of these powerful tools, AREVA is taking benefit of its interdisciplinary know-how and international teamwork. Experienced engineers of different technical backgrounds are working together to ensure an appropriate interpretation of the calculation results, uncertainty analysis, along with continuously maintaining and enhancing the quality of the analysis methodologies. In this paper, an overview of AREVA’s broad application experience as well as the broad validation
Development of water packing mitigation scheme for MARS 3- dimensional thermal-hydraulic module
Water packing mitigation scheme was developed to enhance the numerical stability and calculational efficiency of MARS 3-dimensional thermal-hydraulic module. The water packing phenomena is unphysical pressure spike which occurs in a two-phase system thermal-hydraulic code using Eulerian finite difference method. Great velocities developed from large pressure spike slow down the calculation efficiency due to the stability limit. Also, large pressure spike and subsequent low pressure can make errors in thermodynamic state table search. The developed water packing mitigation scheme was implemented in MARS3D module. It is shown from the results of some benchmark problema that numerical stability and calculational efficiency were improved
3 dimensional volume MR imaging of intratemporal facial nerve
Seo, Jeong Jin; Kang, Heoung Keun; Kim, Hyun Ju; Kim, Jae Kyu; Jung, Hyun Ung; Moon, Woong Jae [Chonnam University Medical School, Kwangju (Korea, Republic of)
1994-10-15
To evaluate the usefulness of 3 dimensional volume MR imaging technique for demonstrating the facial nerves and to describe MR findings in facial palsy patients and evaluate the significance of facial nerve enhancement. We reviewed the MR images of facial nerves obtained with 3 dimensional volume imaging technique before and after intravenous administration of Gadopentetate dimeglumine in 13 cases who had facial paralysis and 33 cases who had no facial palsy. And we analyzed the detectability of ananatomical segments of intratemporal facial nerves and facial nerve enhancement. When the 3 dimensional volume MR images of 46 nerves were analyzed subjectively, the nerve courses of 43(93%) of 46 nerves were effectively demonstrated on 3 dimensional volume MR images. Internal acoustic canal portions and geniculate ganglion of facial nerve were well visualized on axial images and tympanic and mastoid segments were well depicted on oblique sagittal images. 10 of 13 patients(77%) were visibly enhanced along at least one segment of the facial nerve with swelling or thickening, and nerves of 8 of normal 33 cases(24%) were enhanced without thickening or swelling. MR findings of facial nerve parelysis is asymmetrical thickening of facial nerve with contrast enhancement. The 3 dimensional volume MR imaging technique should be a useful study for the evaluation of intratemporal facial nerve disease.
Use of 3-dimensional body scans for body-image research.
Domina, Tanya; Heuberger, Roschelle; MacGillivray, Maureen
2008-04-01
This preliminary study explored the use of highly realistic 3-dimensional body-scan images as a potential tool, taking advantage of a much more specific and expanded representation of the entire body. Traditionally, body-image research makes use of various contour drawing scales whose 2-dimensional figures increase proportionately and do not match the shape of many women. The study tested whether body-scanned images (N = 85) could be consistently "matched" to individual figures on a contour drawing scale. Internal consistency and interrater reliability were calculated and high coefficients were observed (alpha = .97, kappa = .80). The potential of utilizing 3-dimensional images either as more realistic somatotypes in contour-rating scales or as a measurement of body-image satisfaction using computer manipulation of a digital image is discussed. PMID:18556919
Differential Cross Section Kinematics for 3-dimensional Transport Codes
Norbury, John W.; Dick, Frank
2008-01-01
In support of the development of 3-dimensional transport codes, this paper derives the relevant relativistic particle kinematic theory. Formulas are given for invariant, spectral and angular distributions in both the lab (spacecraft) and center of momentum frames, for collisions involving 2, 3 and n - body final states.
Controlled teleportation of a 3-dimensional bipartite quantum state
Cao, Hai-Jing; Chen, Zhong-Hua; Song, He-Shan
2008-07-01
A controlled teleportation scheme of an unknown 3-dimensional (3D) two-particle quantum state is proposed, where a 3D Bell state and 3D GHZ state function as the quantum channel. This teleportation scheme can be directly generalized to teleport an unknown d-dimensional bipartite quantum state.
Controlled teleportation of a 3-dimensional bipartite quantum state
Cao Haijing; Chen Zhonghua [Physics Department, Shanghai University of Electric Power, Shanghai 201300 (China); Song Heshan [Physics Department, Dalian University of Technology, Dalian 116024 (China)], E-mail: 2007000084@shiep.edu.cn
2008-07-15
A controlled teleportation scheme of an unknown 3-dimensional (3D) two-particle quantum state is proposed, where a 3D Bell state and 3D GHZ state function as the quantum channel. This teleportation scheme can be directly generalized to teleport an unknown d-dimensional bipartite quantum state.
2 and 3-dimensional Hamiltonians with Shape Invariance Symmetry
Jafarizadeh, M. A.; Panahi-Talemi, H.; Faizi, E.
2000-01-01
Via a special dimensional reduction, that is, Fourier transforming over one of the coordinates of Casimir operator of su(2) Lie algebra and 4-oscillator Hamiltonian, we have obtained 2 and 3 dimensional Hamiltonian with shape invariance symmetry. Using this symmetry we have obtained their eigenspectrum. In the mean time we show equivalence of shape invariance symmetry and Lie algebraic symmetry of these Hamiltonians.
3-Dimensional reconstruction of fluorescent structures in tardigrades
Franz BRÜMMER
2007-09-01
Full Text Available Tardigrades are microscopic animals, thus brightfield microscopy is a well established method for tardigrade observation. Modern techniques in functional genetics like fluorescence in situ hybridisation or fluorescently labelled expression markers demand high resolution fluorescence microscopy. Nevertheless tardigrades are still considered to be difficult objects for fluorescence techniques as they are covered by an opaque and diffracting cuticle. We show a modern technique of structured light illumination that enables us to acquire thin optical sections and consequently to reconstruct 3-dimensional structures in tardigrades with a high spatial resolution in all 3 dimensions. This technique is evaluated on taxonomically valuable internal as well as external structures of eutardigrades: the bucco-pharyngeal apparatus and the claws. The 3-dimensional reconstructions allow the measurement of distances in all 3 dimensions.
Catalytic carbon deposition on 3-dimensional carbon fibre supports
Thornton, Matthew James
2005-01-01
Catalytic carbon deposition reactions, using methane, ethane or synthetic natural gas (1.8 vol. % propane, 6.7 vol. % ethane and balance methane) as the carbon-containing gas feedstock with or without the addition of hydrogen, have been investigated over nickel, cobalt and iron catalysts supported on 3-dimensional carbon fibre supports, using both a horizontal tube furnace and an isothermal, isobaric induction furnace. The transition metal catalysts were prepared by impregnating 3-dimens...
Anti-de Sitter 3-dimensional Gravity with Torsion
Blagojevic, M; Vasilic, M.
2004-01-01
Using the canonical formalism, we study the asymptotic symmetries of the topological 3-dimensional gravity with torsion. In the anti-de Sitter sector, the symmetries are realized by two independent Virasoro algebras with classical central charges. In the simple case of the teleparallel vacuum geometry, the central charges are equal to each other and have the same value as in general relativity, while in the general Riemann-Cartan geometry, they become different.
GLOBAL STABILITY IN TIME-DELAYED 3-DIMENSIONAL RICHARDS MODEL
无
2010-01-01
We obtain the global attractivity and global asymptotical stability of positive equilibria to a 3-dimensional Richards model with delays. Our results do not depend on the size-asymmetry parameter which measures the degree of the curvature of size-growth among individuals over the entire growth curve, and the shape parameter which affects the shape of model curve. Lastly, we gave a numerical simulation to verify the feasibility of our main results.
Circuit-Switched Gossiping in the 3-Dimensional Torus Networks
Delmas, Olivier; Pérennes, Stéphane
1996-01-01
In this paper we describe, in the case of short messages, an efficient gossiping algorithm for 3-dimensional torus networks (wrap-around or toroidal meshes) that uses synchronous circuit-switched routing. The algorithm is based on a recursive decomposition of a torus. The algorithm requires an optimal number of rounds and a quasi-optimal number of intermediate switch settings to gossip in an $7^i \\times 7^i \\times 7^i$ torus.
Invasive 3-Dimensional Organotypic Neoplasia from Multiple Normal Human Epithelia
Ridky, Todd W.; Chow, Jennifer M.; Wong, David J.; Khavari, Paul A
2010-01-01
Refined cancer models are required to assess the burgeoning number of potential targets for cancer therapeutics within a rapid and clinically relevant context. Here we utilize tumor-associated genetic pathways to transform primary human epithelial cells from epidermis, oropharynx, esophagus, and cervix into genetically defined tumors within a human 3-dimensional (3-D) tissue environment incorporating cell-populated stroma and intact basement membrane. These engineered organotypic tissues reca...
Temporal, 3-dimensional, cellular anatomy of corneal wound tissue.
Jester, J V; Petroll, W M; Barry, P. A.; Cavanagh, H D
1995-01-01
We have evaluated temporally the 3-dimensional cellular anatomy of corneal wound tissue in the rabbit eye using in vivo tandem scanning confocal microscopy. In vivo microscopic studies showed that corneal fibroblast migrated into the wound as an interconnected cellular meshwork with long, thin, randomly oriented cell processes. Interconnection of fibroblasts was further confirmed by localisation of monoclonal antibodies to connexin 43 which demonstrated prominent staining of putative gap junc...
LWR core safety analysis with Areva's 3-dimensional methods
The quality of the safety analysis strongly affects the confidence in the operational safety of a reactor. To ensure the highest quality, it is essential that the methodology consists of appropriate analysis tools and an extensive validation base. Sophisticated 3-dimensional core models ensure that all physical effects relevant for safety are treated and the results are reliable and conservative. The validation base includes measurement campaigns in test facilities and comparisons of the predictions of steady state and transient measured data gathered from plants during many years of operation. Thus, the core models achieve reliable and comprehensive results for a wide range of applications. As an example an overview of the application experience as well as the validation base of AREVA's 3-dimensional codes is given. The importance and necessity of the comprehensive 3-dimensional methodology is illustrated with examples of a BWR and PWR safety analysis. For BWR transient application the analysis of regional power oscillations is considered and regarding the PWR safety analysis an example referring to fast enthalpy rise and the maximum fuel temperature caused by a rod ejection accident is shown. (orig.)
Tracking Error analysis of Concentrator Photovoltaic Module Using Total 3-Dimensional Simulator
Ota, Yasuyuki; Nishioka, Kensuke
2011-12-01
A 3-dimensional (3D) operating simulator for concentrator photovoltaic (CPV) module using triple-junction solar cell was developed. By connecting 3D equivalent circuit simulation for triple-junction solar cell and ray-trace simulation for optics model, the operating characteristics of CPV module were calculated. A typical flat Fresnel lens and homogenizer were adapted to the optics model. The influence of tracking error on the performance of CPV module was calculated. There was the correlation between the optical efficiency and Isc. However, Pm was not correlated with these values, and was strongly dependent on FF. We can use this total simulator for the evaluation and optimization from the light incidence to operating characteristic of CPV modules.
Reference Trajectory Generation for 3-Dimensional Walking of a Humanoid Robot
无
2007-01-01
Humanoid walking planning is a complicated task because of the high number of degrees of freedom (DOFs) and the variable mechanical structure during walking. In this paper, a planning method for 3-dimensional (3-D) walking movements was developed based on a model of a typical humanoid robot with 12 DOFs on the lower body. The planning process includes trajectory generation for the hip, ankle, and knee joints in the Cartesian space. The balance of the robot was ensured by adjusting the hip motion. The angles for each DOF were obtained from 3-D kinematics calculation. The calculation gave reference trajectories of all the DOFs on the humanoid robot which were used to control the real robot. The simulation results show that the method is effective.
Incorporating interactive 3-dimensional graphics in astronomy research papers
Barnes, David G
2007-01-01
Most research data collections created or used by astronomers are intrinsically multi-dimensional. In contrast, all visual representations of data presented within research papers are exclusively 2-dimensional. We present a resolution of this dichotomy that uses a novel technique for embedding 3-dimensional (3-d) visualisations of astronomy data sets in electronic-format research papers. Our technique uses the latest Adobe Portable Document Format extensions together with a new version of the S2PLOT programming library. The 3-d models can be easily rotated and explored by the reader and, in some cases, modified. We demonstrate example applications of this technique including: 3-d figures exhibiting subtle structure in redshift catalogues, colour-magnitude diagrams and halo merger trees; 3-d isosurface and volume renderings of cosmological simulations; and 3-d models of instructional diagrams and instrument designs.
Scientific visualization of 3-dimensional optimized stellarator configurations
The design techniques and physics analysis of modern stellarator configurations for magnetic fusion research rely heavily on high performance computing and simulation. Stellarators, which are fundamentally 3-dimensional in nature, offer significantly more design flexibility than more symmetric devices such as the tokamak. By varying the outer boundary shape of the plasma, a variety of physics features, such as transport, stability, and heating efficiency can be optimized. Scientific visualization techniques are an important adjunct to this effort as they provide a necessary ergonomic link between the numerical results and the intuition of the human researcher. The authors have developed a variety of visualization techniques for stellarators which both facilitate the design optimization process and allow the physics simulations to be more readily understood
Protalign: a 3-dimensional protein alignment assessment tool.
Meads, D; Hansen, M D; Pang, A
1999-01-01
Protein fold recognition (sometimes called threading) is the prediction of a protein's 3-dimensional shape based on its similarity to a protein of known structure. Fold predictions are low resolution; that is, no effort is made to rotate the protein's component amino acid side chains into their correct spatial orientations. The goal is simply to recognize the protein family member that most closely resembles the target sequence of unknown structure and to create a sensible alignment of the target to the known structure (i.e., a structure-sequence alignment). To facilitate this type of structure prediction, we have designed a low resolution molecular graphics tool. ProtAlign introduces the ability to interact with and edit alignments directly in the 3-dimensional structure as well as in the usual 2-dimensional layout. It also contains several functions and features to help the user assess areas within the alignment. ProtAlign implements an open pipe architecture to allow other programs to access its molecular graphics capabilities. In addition, it is capable of "driving" other programs. Because amino acid side chain orientation is not relevant in fold recognition, we represent amino acid residues as abstract shapes or glyphs much like Lego (tm) blocks and we borrow techniques from comparative flow visualization using streamlines to provide clean depictions of the entire protein model. By creating a low resolution representation of protein structure, we are able to at least double the amount of information on the screen. At the same time, we create a view that is not as busy as the corresponding representations using traditional high resolution visualization methods which show detailed atomic structure. This eliminates distracting and possibly misleading visual clutter resulting from the mapping of protein alignment information onto a high resolution display of the known structure. This molecular graphics program is implemented in Open GL to facilitate porting to
YAN Xing-fei; He Shuan-hai; SUN limin
2003-01-01
The text include two aspects, one is the general finite element method (FEM), the other is bridge special FEM. And two viewpoints are used in it, one is the theory of FEM, the other is the practical program-making. The virtual laminated 3 dimensional degenerated element with vivid character is introduced in this paper and a large-scale computer program of FEM is manufactured. 1In addition, some current advantaged computer technology is used to make simple pre- and post processing program in order to exemplify and calculate easily in the process of researching. By using a factual example, the text also prove the method simply and resultful for analyze of bridge.
The 3-dimensional construction of the Rae craton, central Canada
Snyder, David B.; Craven, James A.; Pilkington, Mark; Hillier, Michael J.
2015-10-01
Reconstruction of the 3-dimensional tectonic assembly of early continents, first as Archean cratons and then Proterozoic shields, remains poorly understood. In this paper, all readily available geophysical and geochemical data are assembled in a 3-D model with the most accurate bedrock geology in order to understand better the geometry of major structures within the Rae craton of central Canada. Analysis of geophysical observations of gravity and seismic wave speed variations revealed several lithospheric-scale discontinuities in physical properties. Where these discontinuities project upward to correlate with mapped upper crustal geological structures, the discontinuities can be interpreted as shear zones. Radiometric dating of xenoliths provides estimates of rock types and ages at depth beneath sparse kimberlite occurrences. These ages can also be correlated to surface rocks. The 3.6-2.6 Ga Rae craton comprises at least three smaller continental terranes, which "cratonized" during a granitic bloom. Cratonization probably represents final differentiation of early crust into a relatively homogeneous, uniformly thin (35-42 km), tonalite-trondhjemite-granodiorite crust with pyroxenite layers near the Moho. The peak thermotectonic event at 1.86-1.7 Ga was associated with the Hudsonian orogeny that assembled several cratons and lesser continental blocks into the Canadian Shield using a number of southeast-dipping megathrusts. This orogeny metasomatized, mineralized, and recrystallized mantle and lower crustal rocks, apparently making them more conductive by introducing or concentrating sulfides or graphite. Little evidence exists of thin slabs similar to modern oceanic lithosphere in this Precambrian construction history whereas underthrusting and wedging of continental lithosphere is inferred from multiple dipping discontinuities.
Development and Validation of a 3-Dimensional CFB Furnace Model
Vepsäläinen, Arl; Myöhänen, Karl; Hyppäneni, Timo; Leino, Timo; Tourunen, Antti
At Foster Wheeler, a three-dimensional CFB furnace model is essential part of knowledge development of CFB furnace process regarding solid mixing, combustion, emission formation and heat transfer. Results of laboratory and pilot scale phenomenon research are utilized in development of sub-models. Analyses of field-test results in industrial-scale CFB boilers including furnace profile measurements are simultaneously carried out with development of 3-dimensional process modeling, which provides a chain of knowledge that is utilized as feedback for phenomenon research. Knowledge gathered by model validation studies and up-to-date parameter databases are utilized in performance prediction and design development of CFB boiler furnaces. This paper reports recent development steps related to modeling of combustion and formation of char and volatiles of various fuel types in CFB conditions. Also a new model for predicting the formation of nitrogen oxides is presented. Validation of mixing and combustion parameters for solids and gases are based on test balances at several large-scale CFB boilers combusting coal, peat and bio-fuels. Field-tests including lateral and vertical furnace profile measurements and characterization of solid materials provides a window for characterization of fuel specific mixing and combustion behavior in CFB furnace at different loads and operation conditions. Measured horizontal gas profiles are projection of balance between fuel mixing and reactions at lower part of furnace and are used together with both lateral temperature profiles at bed and upper parts of furnace for determination of solid mixing and combustion model parameters. Modeling of char and volatile based formation of NO profiles is followed by analysis of oxidizing and reducing regions formed due lower furnace design and mixing characteristics of fuel and combustion airs effecting to formation ofNO furnace profile by reduction and volatile-nitrogen reactions. This paper presents
A 3-Dimensional display and process software for THz spectrum
Jiang, Xiaowen; Zhang, Zhaohui; Zhao, Xiaoyan; Yin, Yixin; Ajito, Katsuhiro; Song, Hojin
2011-02-01
An underpinning software is devoted to THz spectrum analyzing and 3-D imaging. The paper describes the software's outline, structure, functions and some of considerations. Users in LAN (local area network) can access it and implement some basic and advanced works such as files operation, echoes cutting, spectrum calculation, baseline cancelling, peak fitting, qualitative and quantitative measuring of solid-state samples.
Novel Radiobiological Gamma Index for Evaluation of 3-Dimensional Predicted Dose Distribution
Sumida, Iori, E-mail: sumida@radonc.med.osaka-u.ac.jp [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Osaka (Japan); Yamaguchi, Hajime; Kizaki, Hisao; Aboshi, Keiko; Tsujii, Mari; Yoshikawa, Nobuhiko; Yamada, Yuji [Department of Radiation Oncology, NTT West Osaka Hospital, Osaka (Japan); Suzuki, Osamu; Seo, Yuji [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Osaka (Japan); Isohashi, Fumiaki [Department of Radiation Oncology, NTT West Osaka Hospital, Osaka (Japan); Yoshioka, Yasuo [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Osaka (Japan); Ogawa, Kazuhiko [Department of Radiation Oncology, NTT West Osaka Hospital, Osaka (Japan)
2015-07-15
Purpose: To propose a gamma index-based dose evaluation index that integrates the radiobiological parameters of tumor control (TCP) and normal tissue complication probabilities (NTCP). Methods and Materials: Fifteen prostate and head and neck (H&N) cancer patients received intensity modulated radiation therapy. Before treatment, patient-specific quality assurance was conducted via beam-by-beam analysis, and beam-specific dose error distributions were generated. The predicted 3-dimensional (3D) dose distribution was calculated by back-projection of relative dose error distribution per beam. A 3D gamma analysis of different organs (prostate: clinical [CTV] and planned target volumes [PTV], rectum, bladder, femoral heads; H&N: gross tumor volume [GTV], CTV, spinal cord, brain stem, both parotids) was performed using predicted and planned dose distributions under 2%/2 mm tolerance and physical gamma passing rate was calculated. TCP and NTCP values were calculated for voxels with physical gamma indices (PGI) >1. We propose a new radiobiological gamma index (RGI) to quantify the radiobiological effects of TCP and NTCP and calculate radiobiological gamma passing rates. Results: The mean RGI gamma passing rates for prostate cases were significantly different compared with those of PGI (P<.03–.001). The mean RGI gamma passing rates for H&N cases (except for GTV) were significantly different compared with those of PGI (P<.001). Differences in gamma passing rates between PGI and RGI were due to dose differences between the planned and predicted dose distributions. Radiobiological gamma distribution was visualized to identify areas where the dose was radiobiologically important. Conclusions: RGI was proposed to integrate radiobiological effects into PGI. This index would assist physicians and medical physicists not only in physical evaluations of treatment delivery accuracy, but also in clinical evaluations of predicted dose distribution.
A 3-dimensional time-resolved photothermal deflection ``Mirage'' method
Astrath, N. G. C.; Malacarne, L. C.; Lukasievicz, G. V. B.; Bernabe, H. S.; Rohling, J. H.; Baesso, M. L.; Shen, J.; Bialkowski, S. E.
2012-02-01
A three-dimensional time-resolved theory and experiment for photothermal deflection spectroscopy is developed. The heat conduction equations for two semi-infinite media consisting of an opaque sample and a fluid are solved considering temperature and energy flux balance conditions for a Gaussian heat source. The time dependent perpendicular deflection signal is calculated and compared to experimental measurements on glassy carbon and copper samples. Excellent agreement with literature values for thermal diffusivity of the samples is found. The transient behavior is analyzed for different coupling fluids.
Probabilistic analysis on fault tolerance of 3-Dimensional mesh networks
王高才; 陈建二; 王国军; 陈松乔
2003-01-01
The probability model is used to analyze the fault tolerance of mesh. To simplify its analysis, it is as-sumed that the failure probability of each node is independent. A 3-D mesh is partitioned into smaller submeshes,and then the probability with which each submesh satisfies the defined condition is computed. If each submesh satis-fies the condition, then the whole mesh is connected. Consequently, the probability that a 3-D mesh is connected iscomputed assuming each node has a failure probability. Mathematical methods are used to derive a relationship be-tween network node failure probability and network connectivity probability. The calculated results show that the 3-D mesh networks can remain connected with very high probability in practice. It is formally proved that when thenetwork node failure probability is boutded by 0.45 %, the 3-D mesh networks of more than three hundred thousandnodes remain connected with probability larger than 99 %. The theoretical results show that the method is a power-ful technique to calculate the lower bound of the connectivity probability of mesh networks.
Yang, Wenming; An, Hui; Amin, Maghbouli; Li, Jing
2014-11-01
A 3-dimensional computational fluid dynamics modeling is conducted on a direct injection diesel engine fueled by biodiesel using multi-dimensional software KIVA4 coupled with CHEMKIN. To accurately predict the oxidation of saturated and unsaturated agents of the biodiesel fuel, a multicomponent advanced combustion model consisting of 69 species and 204 reactions combined with detailed oxidation pathways of methyl decenoate (C11H22O2), methyl-9-decenoate (C11H20O2) and n-heptane (C7H16) is employed in this work. In order to better represent the real fuel properties, the detailed chemical and thermo-physical properties of biodiesel such as vapor pressure, latent heat of vaporization, liquid viscosity and surface tension were calculated and compiled into the KIVA4 fuel library. The nitrogen monoxide (NO) and carbon monoxide (CO) formation mechanisms were also embedded. After validating the numerical simulation model by comparing the in-cylinder pressure and heat release rate curves with experimental results, further studies have been carried out to investigate the effect of combustion chamber design on flow field, subsequently on the combustion process and performance of diesel engine fueled by biodiesel. Research has also been done to investigate the impact of fuel injector location on the performance and emissions formation of diesel engine.
The objectives of this study are (1) to parallelize a 3-dimensional hydrogeochemistry code and (2) to apply the parallel code to a proposed waste disposal site at the Oak Ridge National Laboratory (ORNL). The 2-dimensional hydrogeochemistry code HYDROGEOCHEM, developed at the Pennsylvania State University for coupled subsurface solute transport and chemical equilibrium processes, was first modified to accommodate 3-dimensional problem domains. A bi-conjugate gradient stabilized linear matrix solver was then incorporated to solve the matrix equation. We chose to parallelize the 3-dimensional code on the Intel Paragons at ORNL by using an HPF (high performance FORTRAN) compiler developed at PGI. The data- and task-parallel algorithms available in the HPF compiler proved to be highly efficient for the geochemistry calculation. This calculation can be easily implemented in HPF formats and is perfectly parallel because the chemical speciation on one finite-element node is virtually independent of those on the others. The parallel code was applied to a subwatershed of the Melton Branch at ORNL. Chemical heterogeneity, in addition to physical heterogeneities of the geological formations, has been identified as one of the major factors that affect the fate and transport of contaminants at ORNL. This study demonstrated an application of the 3-dimensional hydrogeochemistry code on the Melton Branch site. A uranium tailing problem that involved in aqueous complexation and precipitation-dissolution was tested. Performance statistics was collected on the Intel Paragons at ORNL. Implications of these results on the further optimization of the code were discussed
Computer-assisted 3-dimensional anthropometry of the scaphoid.
Pichler, Wolfgang; Windisch, Gunther; Schaffler, Gottfried; Heidari, Nima; Dorr, Katrin; Grechenig, Wolfgang
2010-02-01
Scaphoid fracture fixation using a cannulated headless compression screw and the Matti-Russe procedure for the treatment of scaphoid nonunions are performed routinely. Surgeons performing these procedures need to be familiar with the anatomy of the scaphoid. A literature review reveals relatively few articles on this subject. The goal of this anatomical study was to measure the scaphoid using current technology and to discuss the findings with respect to the current, relevant literature.Computed tomography scans of 30 wrists were performed using a 64-slice SOMATOM Sensation CT system (resolution 0.6 mm) (Siemens Medical Solutions Inc, Malvern, Pennsylvania). Three-dimensional reconstructions from the raw data were generated by MIMICS software (Materialise, Leuven, Belgium). The scaphoid had a mean length of 26.0 mm (range, 22.3-30.7 mm), and men had a significantly longer (Pscaphoid than women (27.861.6 mm vs 24.561.6 mm, respectively). The width and height were measured at 3 different levels for volume calculations, resulting in a mean volume of 3389.5 mm(3). Men had a significantly larger (Pscaphoid volume than women (4057.86740.7 mm(3) vs 2846.56617.5 mm(3), respectively).We found considerable variation in the length and volume of the scaphoid in our cohort. We also demonstrated a clear correlation between scaphoid size and sex. Surgeons performing operative fixation of scaphoid fractures and corticocancellous bone grafting for nonunions need to be familiar with these anatomical variations. PMID:20192143
Various approaches to the modelling of large scale 3-dimensional circulation in the Ocean
Shaji, C.; Bahulayan, N.; Rao, A.D; Dube, S.K.
In this paper, the three different approaches to the modelling of large scale 3-dimensional flow in the ocean such as the diagnostic, semi-diagnostic (adaptation) and the prognostic are discussed in detail. Three-dimensional solutions are obtained...
Initial magnetic field configurations for 3-dimensional simulations of astrophysical jets
Jorgensen, M.; R. Ouyed; Christensen, M.
2001-01-01
We solve, and provide analytical expressions, for current-free magnetic configurations in the context of initial setups of 3-dimensional simulations of astrophysical jets involving an accretion disk corona in hydrostatic balance around a central object. These configurations which thread through the accretion disk and its corona preserve the initial hydrostatic state. This work sets stage for future 3-dimensional jet simulations (including disk rotation and mass-load) where launching, accelera...
Observation of a New Magnetic Response in 3-Dimensional Split Ring Resonators under Normal Incidence
Chiam, S. Y.; Bettiol, A. A.; Bahou, M.; Han, J; Moser, H. O.; Watt, F
2008-01-01
So far, research in the field of metamaterials has been carried out largely with arrays of flat, 2-dimensional structures. Here, we report a newly identified magnetic resonance in Split Cylinder Resonators (SCRs), a 3-dimensional version of the Split Ring Resonator (SRR), which were fabricated with the Proton Beam Writing technique. Experimental and numerical results indicate a hitherto unobserved 3-dimensional resonance mode under normal incidence at about 26 THz, when the SCR depth is appro...
The 3-Dimensional q-Deformed Harmonic Oscillator and Magic Numbers of Alkali Metal Clusters
Bonatsos, Dennis; Raychev, P P; Roussev, R P; Terziev, P A; Bonatsos, Dennis
1999-01-01
Magic numbers predicted by a 3-dimensional q-deformed harmonic oscillator with Uq(3) > SOq(3) symmetry are compared to experimental data for alkali metal clusters, as well as to theoretical predictions of jellium models, Woods--Saxon and wine bottle potentials, and to the classification scheme using the 3n+l pseudo quantum number. The 3-dimensional q-deformed harmonic oscillator correctly predicts all experimentally observed magic numbers up to 1500 (which is the expected limit of validity for theories based on the filling of electronic shells), thus indicating that Uq(3), which is a nonlinear extension of the U(3) symmetry of the spherical (3-dimensional isotropic) harmonic oscillator, is a good candidate for being the symmetry of systems of alkali metal clusters.
A Fortran program (RELAX3D) to solve the 3 dimensional Poisson (Laplace) equation
RELAX3D is an efficient, user friendly, interactive FORTRAN program which solves the Poisson (Laplace) equation Λ2=p for a general 3 dimensional geometry consisting of Dirichlet and Neumann boundaries approximated to lie on a regular 3 dimensional mesh. The finite difference equations at these nodes are solved using a successive point-iterative over-relaxation method. A menu of commands, supplemented by HELP facility, controls the dynamic loading of the subroutine describing the problem case, the iterations to converge to a solution, and the contour plotting of any desired slices, etc
Dynamics of large scale 3-dimensional circulation of the Indian Ocean
Swapna, P.
One of the main objective of this thesis is to adapt and configure a fully non-linear, primitive equation type, sigma co-ordinate 3-dimensional circulation model for the entire Indian Ocean area which can be run on diagnostic, semi...
Full 3-dimensional digital workflow for multicomponent dental appliances : A proof of concept
van der Meer, W. Joerd; Vissink, Arjan; Ren, Yijin
2016-01-01
BACKGROUND: The authors used a 3-dimensional (3D) printer and a bending robot to produce a multicomponent dental appliance to assess whether 3D digital models of the dentition are applicable for a full digital workflow. METHODS: The authors scanned a volunteer's dentition with an intraoral scanner (
Fast convergence to an invariant measure for non-intersecting 3-dimensional Brownian paths
Lawler, Gregory F
2010-01-01
We consider pairs of 3-dimensional Brownian paths, started at the origin and conditioned to have no intersections after time zero. We show that there exists a unique measure on pairs of paths that is invariant under this conditioning, while improving the previously known rate of convergence to stationarity.
Rui HUANG; Yang CAO
2011-01-01
In this paper we investigate the initial boundary value problem of Cahn-Hilliard equation with concentration dependent mobility and gradient dependent potential. By the energy method and the theory of Campanato spaces, we prove the existence and the uniqueness of classical solutions in 3-dimensional space.
Adighibe, O; Micklem, K; Campo, L; Ferguson, M.; Harris, A; Pozos, R; Gatter, K; Pezzella, F.
2006-01-01
The nonangiogenic lung tumour is characterized by neoplastic cells co-opting the pre-existent vasculature and filling the alveoli space. 3-Dimensional reconstruction of the tumour reveals that this particular tumour progresses without neovascularization and there is no major destruction of the lung's architectural integrity.
3-dimensional orthodontics visualization system with dental study models and orthopantomograms
Zhang, Hua; Ong, S. H.; Foong, K. W. C.; Dhar, T.
2005-04-01
The aim of this study is to develop a system that provides 3-dimensional visualization of orthodontic treatments. Dental plaster models and corresponding orthopantomogram (dental panoramic tomogram) are first digitized and fed into the system. A semi-auto segmentation technique is applied to the plaster models to detect the dental arches, tooth interstices and gum margins, which are used to extract individual crown models. 3-dimensional representation of roots, generated by deforming generic tooth models with orthopantomogram using radial basis functions, is attached to corresponding crowns to enable visualization of complete teeth. An optional algorithm to close the gaps between deformed roots and actual crowns by using multi-quadratic radial basis functions is also presented, which is capable of generating smooth mesh representation of complete 3-dimensional teeth. User interface is carefully designed to achieve a flexible system with as much user friendliness as possible. Manual calibration and correction is possible throughout the data processing steps to compensate occasional misbehaviors of automatic procedures. By allowing the users to move and re-arrange individual teeth (with their roots) on a full dentition, this orthodontic visualization system provides an easy and accurate way of simulation and planning of orthodontic treatment. Its capability of presenting 3-dimensional root information with only study models and orthopantomogram is especially useful for patients who do not undergo CT scanning, which is not a routine procedure in most orthodontic cases.
Ince, Elif; Kirbaslar, Fatma Gulay; Yolcu, Ergun; Aslan, Ayse Esra; Kayacan, Zeynep Cigdem; Alkan Olsson, Johanna; Akbasli, Ayse Ceylan; Aytekin, Mesut; Bauer, Thomas; Charalambis, Dimitris; Gunes, Zeliha Ozsoy; Kandemir, Ceyhan; Sari, Umit; Turkoglu, Suleyman; Yaman, Yavuz; Yolcu, Ozgu
2014-01-01
The purpose of this study is to develop a 3-dimensional interactive multi-user and multi-admin IUVIRLAB featuring active learning methods and techniques for university students and to introduce the Virtual Laboratory of Istanbul University and to show effects of IUVIRLAB on students' attitudes on communication skills and IUVIRLAB. Although…
Study of new chaotic flows on a family of 3-dimensional systems with quadratic nonlinearities
Based on a wider systematic search on a family of 3-dimensional systems with quadratic nonlinearities, three new simple chaotic systems were found. One of them has the unusual feature of having a stable equilibrium point, and it is the simplest one of other chaotic flows with this property. The others have some interesting special properties
On Maximal Surfaces in Certain Non-Flat 3-Dimensional Robertson-Walker Spacetimes
Romero, Alfonso, E-mail: aromero@ugr.es [Universidad de Granada, Departamento de Geometria y Topologia (Spain); Rubio, Rafael M., E-mail: rmrubio@uco.es [Universidad de Cordoba, Departamento de Matematicas, Campus de Rabanales (Spain)
2012-09-15
An upper bound for the integral, on a geodesic disc, of the squared length of the gradient of a distinguished function on any maximal surface in certain non-flat 3-dimensional Robertson-Walker spacetimes is obtained. As an application, a new proof of a known Calabi-Bernstein's theorem is given.
Clinical advantage and limitation of the 3-dimensional magnetic resonance imaging of the brain
The authors discuss practical techniques of 3-dimensional magnetic resonance images. Raw data for 3-dimensional MRI were acquired using a 3D turbo-FLASH sequence. The data were processed in the following three ways; 1) volume rendering of all the raw data, 2) segmentation of the brain from other tissue using other software and the volume rendering of all the raw data, and 3) reconstruction of 2-dimensional image of the arbitrary orientation (oblique-oblique and curvature) using multi-planar reconstruction (MPR). In addition to these basic techniques, a surgical window technique, maximum intensity projection (MIP), and skin marking using fatty acid gel in capsules can provide the following unique images; 1) surface images of the skin, skull and brain, 2) images of the arteries and the main cortical vein superimposed on the brain-surface images, and 3) surgical images simulating craniotomy. The drawbacks of 3-dimensional MRI at present are twofold; 1)it requires mini-computers, which is not always available at every clinical site, and 2) the time necessary for data processing and image reconstruction depends on the performance of the computer, but in any case the segmentation of the brain from other soft tissue is a time-consuming job, one which generally takes several hours. However, it is expected that these present limitations of 3-dimentional MRI are only temporary because fast and high cost-performance computers for this specific purpose (image processing) have recently become available. The authors stress that the most important factor which drives the development of a high cost-performance system for 3-dimensional MRI is the demand from clinicians, who realize the advantages of 3-dimensional MRI. (author)
New Technique for Developing a Proton Range Compensator With Use of a 3-Dimensional Printer
Ju, Sang Gyu, E-mail: sg.ju@samsung.com [Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Kim, Min Kyu; Hong, Chae-Seon; Kim, Jin Sung; Han, Youngyih; Choi, Doo Ho [Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Shin, Dongho; Lee, Se Byeong [Proton Therapy Center, National Cancer Center, Gyeonggi-do (Korea, Republic of)
2014-02-01
Purpose: A new system for manufacturing a proton range compensator (RC) was developed by using a 3-dimensional printer (3DP). The physical accuracy and dosimetric characteristics of the new RC manufactured by 3DP (RC{sub 3}DP) were compared with those of a conventional RC (RC{sub C}MM) manufactured by a computerized milling machine (CMM). Methods and Materials: An RC for brain tumor treatment with a scattered proton beam was calculated with a treatment planning system, and the resulting data were converted into a new format for 3DP using in-house software. The RC{sub 3}DP was printed with ultraviolet curable acrylic plastic, and an RC{sub C}MM was milled into polymethylmethacrylate using a CMM. The inner shape of both RCs was scanned by using a 3D scanner and compared with TPS data by applying composite analysis (CA; with 1-mm depth difference and 1 mm distance-to-agreement criteria) to verify their geometric accuracy. The position and distal penumbra of distal dose falloff at the central axis and field width of the dose profile at the midline depth of spread-out Bragg peak were measured for the 2 RCs to evaluate their dosimetric characteristics. Both RCs were imaged on a computed tomography scanner to evaluate uniformity of internal density. The manufacturing times for both RCs were compared to evaluate the production efficiency. Results: The pass rates for the CA test were 99.5% and 92.5% for RC{sub 3}DP and RC{sub C}MM, respectively. There was no significant difference in dosimetric characteristics and uniformity of internal density between the 2 RCs. The net fabrication times of RC{sub 3}DP and RC{sub C}MM were about 18 and 3 hours, respectively. Conclusions: The physical accuracy and dosimetric characteristics of RC{sub 3}DP were comparable with those of the conventional RC{sub C}MM, and significant system minimization was provided.
The application of 3-dimensional CAT scan reconstruction for maxillofacial deformities
It has been found very useful to recognize craniofacial deformities 3-dimensionally, and to observe 3-D Cat scan reconstructions that have been performed by others. Thus, starting in 1985, we have developed a 3-D CT system that combines conventional X-ray CAT scan hardware to a 3-Dimensional display software. In this paper we report on our 3-CT system, its basic algorithm, and its basic processes, i.e., the threshold process, the perspective process, the shading process and the display. The mixture shading which we have developed makes 3-D displays clearer and more natural. Also, we have applied our 3-D display to 39 cases of maxillofacial diformities. (author)
Collawn, Sherry S; Mobley, James A; Banerjee, N Sanjib; Chow, Louise T
2016-04-01
Wound healing involves a number of factors that results in the production of a "closed" wound. Studies have shown, in animal models, acceleration of wound healing with the addition of adipose-derived stromal cells (ADSC). The cause for the positive effect which these cells have on wound healing has not been elucidated. We have previously shown that addition of ADSC to the dermal equivalent in 3-dimensional skin cultures accelerates reepithelialization. We now demonstrate that conditioned media (CM) from cultured ADSC produced a similar rate of healing. This result suggests that a feedback from the 3-dimensional epithelial cultures to ADSC was not necessary to effect the accelerated reepithelialization. Mass spectrometry of CM from ADSC and primary human fibroblasts revealed differences in secretomes, some of which might have roles in the accelerating wound healing. Thus, the use of CM has provided some preliminary information on a possible mode of action. PMID:26954733
DYNAMICAL CONSISTENCE IN 3-DIMENSIONAL TYPE-K COMPETITIVE LOTKA-VOLTERRA SYSTEM
无
2012-01-01
A 3-dimensional type-K competitive Lotka-Volterra system is considered in this paper. Two discretization schemes are applied to the system with an positive interior fixed point, and two corresponding discrete systems are obtained. By analyzing the local dynamics of the corresponding discrete system near the interior fixed point, it is showed that this system is not dynamically consistent with the continuous counterpart system.
Energy Sources of the Dominant Frequency Dependent 3-dimensional Atmospheric Modes
Schubert, S.
1985-01-01
The energy sources and sinks associated with the zonally asymmetric winter mean flow are investigated as part of an on-going study of atmospheric variability. Distinctly different horizontal structures for the long, intermediate and short time scale atmospheric variations were noted. In previous observations, the 3-dimensional structure of the fluctuations is investigated and the relative roles of barotropic and baroclinic terms are assessed.
BPS operators from the Wilson loop in the 3-dimensional supersymmetric Chern-Simons theory
Fujita, Mitsutoshi
2009-01-01
We consider the small deformation of the pointlike Wilson loop in the 3-dimensional N=6 superconformal Chern-Simons theory. By Taylor expansion of the pointlike Wilson loop in powers of the loop variables, we obtain the BPS operators that correspond to the excited string states of the dual IIA string theory on the pp wave background. The BPS conditions of the Wilson loop constrain both the loop variables and the forms of the operators obtained in the Taylor expansion.
To ensure reliable operation of superconducting field windings of a superconducting generator it is necessary to screen the field windings from time-varying magnetic fields. An electrothermal shield is used for this screening in order to protect the superconducting material from quench phenomenon. This screening effect is due to the eddy currents in the electrothermal shield. In this paper, these eddy currents in the conducting shell are analyzed numerically by using 3-dimensional indirect boundary integral equation method (IBIEM)
Manufacture of Near Net Shaped 3- Dimensional Components for Industrial Applications
Kennedy, David; Brosnan, Donal
2005-01-01
The development of near net shape 3-Dimensional products for industrial applications has been one main goal for Manufacturing Industries over the last few decades. Processes such as polymer blow moulding and its various stages of development, glass forming, extrusion, forging, centrifugal and sand casting, bulge forming and vacuum forming are typical processes that have contributed to this development. Current practices centre on Surface coatings, Rapid Prototyping, laser forming and nanotech...
Objective: To evaluate 3-dimensional digital subtraction technique in diagnosing and treating the malignant esophageal stenosis. Methods: After oral administration of contrast media, both two-dimensional and three-dimensional digital subtraction radiography of narrowed segment of esophagus were performed in forty patients with malignant esophageal stenosis caused by advanced esophageal carcinoma. The images obtained from 3-dimensional digital subtraction technique were compared with the images of the same patient's conventional esophageal air-barium double contrast pictures and 2-dimensional digital subtraction pictures. The results were analyzed. Results: Three-dimensional digital subtraction images could well display the position of the malignant esophageal stenosis. On the images the lesion's length could be precisely measured, the lesion's ulcer and perforation shape could be clearly demonstrated, and subtler esophageal fistula could be detected, which was very helpful for accurately localizing the lesion and selecting suitable endo-esophageal stent. Conclusion: The 3-dimensional digital subtraction technique is very useful in diagnosing malignant esophageal stenosis. With the help of the 3D images the lesion can be precisely localized and the suitable esophageal stent can be effectively selected and placed. (authors)
Development of a 3-dimensional seismic isolation floor for computer systems
In this paper, we investigated the applicability of a seismic isolation floor as a method for protecting computer systems from strong earthquakes, such as computer systems in nuclear power plants. Assuming that the computer system is guaranteed for 250 cm/s2 of input acceleration in the horizontal and vertical directions as the seismic performance, the basic design specification of the seismic isolation floor is considered as follows. Against S1 level earthquakes, the maximum acceleration response of the seismic isolation floor in the horizontal and vertical directions is kept less than 250 cm/s2 to maintain continuous computer operation. Against S2 level earthquakes, the isolation floor allows large horizontal movement and large displacement of the isolation devices to reduce the acceleration response, although it is not guaranteed to be less than 250 cm/s2. By reducing the acceleration response, however, serious damage to the computer systems is reduced, so that they can be restarted after an earthquake. Usually, seismic isolation floor systems permit 2-dimensional (horizontal) isolation. However, in the case of just-under-seated earthquakes, which have large vertical components, the vertical acceleration response of this system is amplified by the lateral vibration of the frame of the isolation floor. Therefore, in this study a 3-dimensional seismic isolation floor, including vertical isolation, was developed. This paper describes 1) the experimental results of the response characteristics of the 3-dimensional seismic isolation floor built as a trial using a 3-dimensional shaking table, and 2) comparison of a 2-dimensional analytical model, for motion in one horizontal direction and the vertical direction, to experimental results. (J.P.N.)
Rahn, Helene, E-mail: helene.rahn@gmail.com [Institute of Fluid Mechanics, Chair of Magnetofluiddynamics, Technische Universitaet Dresden, Dresden 01069 (Germany); Alexiou, Christoph [ENT-Department, Section for Experimental Oncology and Nanomedicine (Else Kröner-Fresenius-Stiftungsprofessur), University Hospital Erlangen, Waldstraße 1, Erlangen 91054 (Germany); Trahms, Lutz [Physikalisch-Technische Bundesanstalt, Abbestraße 2-12, Berlin 10587 (Germany); Odenbach, Stefan [Institute of Fluid Mechanics, Chair of Magnetofluiddynamics, Technische Universitaet Dresden, Dresden 01069 (Germany)
2014-06-01
X-ray computed tomography is nowadays used for a wide range of applications in medicine, science and technology. X-ray microcomputed tomography (XµCT) follows the same principles used for conventional medical CT scanners, but improves the spatial resolution to a few micrometers. We present an example of an application of X-ray microtomography, a study of 3-dimensional biodistribution, as along with the quantification of nanoparticle content in tumoral tissue after minimally invasive cancer therapy. One of these minimal invasive cancer treatments is magnetic drug targeting, where the magnetic nanoparticles are used as controllable drug carriers. The quantification is based on a calibration of the XµCT-equipment. The developed calibration procedure of the X-ray-µCT-equipment is based on a phantom system which allows the discrimination between the various gray values of the data set. These phantoms consist of a biological tissue substitute and magnetic nanoparticles. The phantoms have been studied with XµCT and have been examined magnetically. The obtained gray values and nanoparticle concentration lead to a calibration curve. This curve can be applied to tomographic data sets. Accordingly, this calibration enables a voxel-wise assignment of gray values in the digital tomographic data set to nanoparticle content. Thus, the calibration procedure enables a 3-dimensional study of nanoparticle distribution as well as concentration. - Highlights: • Local cancer treatments are promising in reducing negative side effects occurring during conventional chemotherapy. • The nanoparticles play an important role in delivering drugs to the designated area during local cancer treatments as magnetic drug targeting. • We study the nanoparticles distribution in tumor tissue after magnetic drug targeting with X-ray computed tomography. • We achieved a 3-dimensional quantification of the nanoparticles content in tumor tissue out of digital tomographic data.
Recently, in photo electronic devices industry, titanium oxide which was known to have good optical and electrical characteristic's been studied in the microstructural aspect to increase the conversion efficiency, such as making variable architecture, coating the titanium oxide nano-tube with the quantum dots which have higher band gap materials than this, etc. However, the process of making 3-dimensional titanium oxide structure with general deposition system such as hydrothermal growth, CVO, PVD and ALD had more variables and longer time consumption to make nano structures than electron beam irradiation case. Herein, we proceed with making new titanium oxide nano-screen-testing electron beam irradiation. The metal alkoxide composed of the 1 mol of titanium iso-propoxide and the 1 mol of acetylation reacted with water in propylene glycol methyl ether acetate and isopropyl alcohol solvent. After this process which made the bonding among Ti, O and other organics, the polymer solution was deposited on various types of substrate, such as anodized aluminum oxide mail. Kist. ac., Ag nano dots on SiO2 thin film, Au nano dots on SiO2 thin film, etc. The electron beam irradiation was progressed with the vertical accelerator facility of EB tech which was the company in Dijon, Korea The shape, microstructure and chemical composition of the irradiated polymers were characterized using TEM, XRD, Sem and EDS. The three types of Ti-Ox 3-dimensional structure were made; nano dot cluster, spike-like structure and dendrite structure. Each type of these structures was composed of different mircrostructures. Especially, the formation the 3-dimensional structures via electron beam irradiation was not only effected by the electron beam irradiation conditions but also effected by solution concentrate, conductivity and surface energy of substrate
BPS operators from the Wilson loop in the 3-dimensional supersymmetric Chern-Simons theory
Fujita, Mitsutoshi
2009-01-01
We consider the small deformation of the point-like Wilson loop in the 3-dimensional $\\mathcal{N}=6$ superconformal Chern-Simons theory. By Taylor expansion of the point-like Wilson loop in powers of the loop variables, we obtain the BPS operators that correspond to the excited string states of the dual IIA string theory on the pp wave background. The BPS conditions of the Wilson loop constrain both the loop variables and the forms of the operators obtained in the Taylor expansion.
Screening for proximal coronary artery anomalies with 3-dimensional MR coronary angiography
Prakken, Niek H.; Cramer, Maarten J; Olimulder, Marlon A; Agostoni, Pierfrancesco; Mali, Willem P; Velthuis, Birgitta K
2010-01-01
Under 35 years of age, 14% of sudden cardiac death in athletes is caused by a coronary artery anomaly (CAA). Free-breathing 3-dimensional magnetic resonance coronary angiography (3D-MRCA) has the potential to screen for CAA in athletes and non-athletes as an addition to a clinical cardiac MRI protocol. A 360 healthy men and women (207 athletes and 153 non-athletes) aged 18–60 years (mean age 31 ± 11 years, 37% women) underwent standard cardiac MRI with an additional 3D-MRCA within a maximum o...
Fractal dimensions from a 3-dimensional intermittency analysis in e+e- annihilation
The intermittency structure of multihadronic e+e- annihilation is analyzed by evaluating the factorial moments F2-F5 in 3-dimensional Lorentz invariant phase space as a function of the resolution scale. We interpret our data in the language of fractal objects. It turns out that the fractal dimension depends on the resolution scale in a way that can be attributed to geometrical resolution effects and dynamical effects, such as the π0 Dalitz decay. The LUND 7.2 hadronization model provides an excellent description of the data. There is no indication of unexplained multiplicity fluctuations in small phase space regions. (orig.)
Visualized fuelling process and 3 dimensional reactivity device and core monitor
A new reactor fueling animated graphical display and a 3 dimensional view of the reactor core display are presented that are useful for the physics fuelling engineer, the Control Room Operators, the fuel handling operators and the fuel handling support engineers. Data is downloaded from the online fuelling computer to a data server that is network accessible. The fuelling display and 3Dview display can run on any network connected Computer. The animated graphical fuelling display offers a huge reduction in cognitive workload for all users. The authors recommend that animated graphical displays be developed and utilized wherever personnel have to visualize complex equipment operation. (author)
Development of a 3-Dimensional Dosimetry System for Leksell Gamma Knife-Perfexion
Yoon, KyoungJun; Kwak, Jungwon; Lee, DoHeui; Cho, Byungchul; Lee, Sangwook; Ahn, SeungDo
2015-01-01
The purpose of our study is to develop a new, 3-dimensional dosimetry system to verify the accuracy of dose deliveries in Leksell Gamma Knife-Perfexion TM (LGKP) (Elekta, Norcross, GA, USA). The instrument consists of a moving head phantom, an embedded thin active layer and a CCD camera system and was designed to be mounted to LGKP. As an active material concentrically located in the hemispheric head phantom, we choose Gafchromic EBT3 films and Gd2O2S;Tb phosphor sheets for dosimetric measure...
Shaking test of 3-dimensional isolator by using air spring and rubber bearing
A new 3-dimensional isolator is proposed, where a high-pressure air spring is mounted on a laminated rubber bearing. The vertical flexibility is induced by the air spring, while the horizontal one is primarily by the laminated rubber bearing. To examine the effectiveness of the above concept, shaking tests of experimental models were performed, where a concrete block weighing about 24 tons was mounted on the four isolators. For suppressing rocking motions, an inclined support method was also tested. The results were satisfactory and the effectiveness of new isolators was confirmed
A novel solar cell fabricated with spiral photo-electrode for capturing sunlight 3-dimensionally
LIU; Yong; SHEN; Hui
2006-01-01
A novel solar cell fabricated with spiral photo-electrode for capturing sunlight 3-dimensionally (3D-cell) is proposed in this paper. We studied its performance both in solar simulator and in nature sunlight. Spiral photo-electrode of 3D-cell can receive sunlight from all directions and therefore can track the sun passively. And it is much insensitive to solar azimuth angle and shade. In addition, it increases the area to obtain scattered sunlight and reflected light. Compared with the dye-sensitized solar cells using sandwich structure, it would be more advantageous in the sealing technique.
Hamiltonian Analysis of 3-Dimensional Connection Dynamics in Bondi-like Coordinates
Huang, Chao-Guang
2016-01-01
The Hamiltonian analysis for a 3-dimensional $SO(1,1)\\times T_+$-connection dynamics is conducted in a Bondi-like coordinate system.A null coframe with 5 independent variables and 9 connection coefficients are treated as basic configuration variables.All constraints and their consistency conditions, as well as the equations of motion,for the system are presented.There is no physical degree of freedom in the system as expected.The Ba\\~nados-Teitelboim-Zanelli spacetime as an example is used to check the analysis.
Braverman, Alexander; Nakajima, Hiraku
2016-01-01
Consider the $3$-dimensional $\\mathcal N=4$ supersymmetric gauge theory associated with a compact Lie group $G_c$ and its quaternionic representation $\\mathbf M$. Physicists study its Coulomb branch, which is a noncompact hyper-K\\"ahler manifold with an $\\mathrm{SU}(2)$-action, possibly with singularities. We give a mathematical definition of the Coulomb branch as an affine algebraic variety with $\\mathbb C^\\times$-action when $\\mathbf M$ is of a form $\\mathbf N\\oplus\\mathbf N^*$, as the second step of the proposal given in arXiv:1503.03676.
Spinorial Characterizations of Surfaces into 3-dimensional Pseudo-Riemannian Space Forms
We give a spinorial characterization of isometrically immersed surfaces of arbitrary signature into 3-dimensional pseudo-Riemannian space forms. This generalizes a recent work of the first author for spacelike immersed Lorentzian surfaces in ℝ2,1 to other Lorentzian space forms. We also characterize immersions of Riemannian surfaces in these spaces. From this we can deduce analogous results for timelike immersions of Lorentzian surfaces in space forms of corresponding signature, as well as for spacelike and timelike immersions of surfaces of signature (0, 2), hence achieving a complete spinorial description for this class of pseudo-Riemannian immersions.
The usefulness of 3-dimensional CT angiography for surgeries at the craniovertebral junction
We preoperatively examined 77 patients for VA anomalies by 3-dimensional computed tomography angiography (3D-CTA) in order to avoid intraoperative vertebral artery (VA) injury during instrumentation surgery at the craniovertebral junction. An abnormal course of the VA in the extraosseous region was detected in 10 patients (13.0%), and a high-riding VA was identified in 21 patients (27.3%). The incidence of VA anomalies in the extraosseous and intraosseous regions was higher in patients with a congenital skeletal anomaly at the craniovertebral junction. Preoperative 3D-CTA allowed precise identification of anomalous VAs and reduction of the risk of intraoperative injury of the VA. (author)
Değer, Yalçın; Adigüzel, Özkan; Özer, Senem Yiğit; Kaya, Sadullah; Polat, Zelal Seyfioğlu; Bozyel, Bejna
2015-01-01
Background The mouth is exposed to thermal irritation from hot and cold food and drinks. Thermal changes in the oral cavity produce expansions and contractions in tooth structures and restorative materials. The aim of this study was to investigate the effect of temperature and stress distribution on 2 different post systems using the 3-dimensional (3D) finite element method. Material/Methods The 3D finite element model shows a labio-lingual cross-sectional view of the endodontically treated upper right central incisor and supporting periodontal ligament with bone structures. Stainless steel and glass fiber post systems with different physical and thermal properties were modelled in the tooth restored with composite core and ceramic crown. We placed 100 N static vertical occlusal loading onto the center of the incisal surface of the tooth. Thermal loads of 0°C and 65°C were applied on the model for 5 s. Temperature and thermal stresses were determined on the labio-lingual section of the model at 6 different points. Results The distribution of stress, including thermal stress values, was calculated using 3D finite element analysis. The stainless steel post system produced more temperature and thermal stresses on the restorative materials, tooth structures, and posts than did the glass fiber reinforced composite posts. Conclusions Thermal changes generated stresses in the restorative materials, tooth, and supporting structures. PMID:26615495
This meta-analysis aims to ascertain the significance of early lung toxicity with 3-Dimensional (3D) conformal irradiation for breast carcinomas and identify the sub-groups of patients with increased risk. Electronic databases, reference sections of major oncological textbooks and identified studies were searched for synonyms of breast radiotherapy and radiation pneumonitis (RP). Major studies in thoracic irradiation were reviewed to identify factors frequently associated with RP. Meta-analysis for RP incidence estimation and odds ratio calculation were carried out. The overall incidence of Clinical and Radiological RP is 14% and 42% respectively. Ten studies were identified. Dose-volume Histogram (DVH) related dosimetric factors (Volume of lung receiving certain dose, Vdose and Mean lung Dose, MLD), supraclavicular fossa (SCF) irradiation and age are significantly associated with RP, but not sequential chemotherapy and concomitant use of Tamoxifen. A poorly powered study in IMN group contributed to the negative finding. Smoking has a trend towards protective effect against RP. Use of other modalities may be considered when Ipsilateral lung V20Gy > 30% or MLD > 15 Gy. Extra caution is needed in SCF and IMN irradiation as they are likely to influence these dosimetric parameters
Automated, non-linear registration between 3-dimensional brain map and medical head image
In this paper, we propose an automated, non-linear registration method between 3-dimensional medical head image and brain map in order to efficiently extract the regions of interest. In our method, input 3-dimensional image is registered into a reference image extracted from a brain map. The problems to be solved are automated, non-linear image matching procedure, and cost function which represents the similarity between two images. Non-linear matching is carried out by dividing the input image into connected partial regions, transforming the partial regions preserving connectivity among the adjacent images, evaluating the image similarity between the transformed regions of the input image and the correspondent regions of the reference image, and iteratively searching the optimal transformation of the partial regions. In order to measure the voxelwise similarity of multi-modal images, a cost function is introduced, which is based on the mutual information. Some experiments using MR images presented the effectiveness of the proposed method. (author)
MR imaging of the knee joint with 3-dimensional gradient echo
Authors considered and discussed whether various lesions of the knee joint can be diagnosed under the MR imaging condition with a pulse sequence of 3-dimensional fourier transformed gradient recalled acquisition in the steady state and what advantages the method has. The apparatus was 1.5T Signa (General Electric) equipped with surface coil for the knee. The consecutive 124 sagittal images of 0.8 mm thickness taken primarily for 3-dimensional reconstruction were processed to give any cross sections of coronary, horizontal, sagittal or further additional ones. Subjects were 243 knees (138 internal derangement and 105 osteoarthritis) whose lesions were confirmed by arthroscope or by arthrostomy after the MR imaging. Comparison of the MR imaging and surgical finding revealed that accuracy, specificity and sensitivity of the present MR imaging method were all >90% for diagnosis of internal derangement of anterior cruciate ligament and meniscus. For osteoarthritis, the method was thought useful for evaluation of the depth of cartilage deficit. (K.H.)
Contactless 2-dimensional laser sensor for 3-dimensional wire position and tension measurements
Prall, Matthias; Joehren, R; Ortjohann, H W; Reinhardt, M; Weinheimer, Ch
2009-01-01
We have developed a contact-free 2-dimensional laser sensor with which the position of wires can be measured in 3 dimensions with an accuracy of better than 10 micrometer and with which the tension of the wires can be determined with an accuracy of 0.04 N. These measurements can be made from a distance of 15 cm. The sensor consists of commercially available laser pointers, lenses, color filters and photodiodes. In our application we have used this laser sensor together with an automated 3 dimensional coordinate table. For a single position measurement, the laser sensor is moved by the 3-dimensional coordinate table in a plane and determines the coordinates at which the wires intersect with this plane. The position of the plane itself (the third coordinate) is given by the third axis of the measurement table which is perpendicular to this plane. The control and readout of the table and the readout of the laser sensor were realized with LabVIEW. The precision of the position measurement in the plane was determi...
Crossover from 2-dimensional to 3-dimensional aggregations of clusters on square lattice substrates
Cheng, Yi; Zhu, Yu-Hong; Pan, Qi-Fa; Yang, Bo; Tao, Xiang-Ming; Ye, Gao-Xiang
2015-11-01
A Monte Carlo study on the crossover from 2-dimensional to 3-dimensional aggregations of clusters is presented. Based on the traditional cluster-cluster aggregation (CCA) simulation, a modified growth model is proposed. The clusters (including single particles and their aggregates) diffuse with diffusion step length l (1 ≤ l ≤ 7) and aggregate on a square lattice substrate. If the number of particles contained in a cluster is larger than a critical size sc, the particles at the edge of the cluster have a possibility to jump onto the upper layer, which results in the crossover from 2-dimensional to 3-dimensional aggregations. Our simulation results are in good agreement with the experimental findings. Project supported by the National Natural Science Foundation of China (Grant Nos. 11374082 and 11074215), the Science Foundation of Zhejiang Province Department of Education, China (Grant No. Y201018280), the Fundamental Research Funds for Central Universities, China (Grant No. 2012QNA3010), and the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20100101110005).
Morphological Control of Cells on 3-Dimensional Multi-Layer Nanotopographic Structures.
Jeong, Heon-Ho; Noh, Young-Mu; Song, Hwan-Moon; Lee, Sang-Ho; Park, Jin-Sung; Lee, Chang-Soo
2015-05-01
The extracellular matrix (ECM) environment is known to play an important role in the process of various cell regulatory mechanisms. We have investigated the ability of 3-dimensional ECM geometries to induce morphological changes in cells. Bi-layer polymeric structures with submicron scale stripe patterns were fabricated using a two-step nano-imprinting technique, and the orientation angle (θ(α)) of the upper layer was controlled by changing its alignment with respect to the orientation of the bottom layer. When cells were grown on the mono-layer stripe structure with a single orientation, they elongated along the direction of the stripe pattern. On bi-layer polymer structures, the cell morphologies gradually changed and became rounded, with an increase of θα up to 90 degrees, but the polarities of these cells were still aligned along the orientation of the upper layer. As a result, we show that the polarity and the roundness of cells can be independently regulated by adjusting the orientation of 3-dimensional hierarchical ECM topography. PMID:26505024
Unobservable Problem of Target Tracking with Bearing-only Measurements in 3-dimensional Space
XU Zhi-gang; SHENG An-dong
2008-01-01
The bearings-only tracking (BOT) system is said to be observability if and only if the target motion parameters can be uniquely determined by noise-free bearing measurements. By utilizing the method of orthogonal vectors and characteristic of linear matrix equation, the problem of observability for BOT in noise-free bearings measurements from single observer is discussed based on the target and observer traveling in the 3-dimensional space. A proposition that BOT for target and observer traveling in the 3-dimensional space with constant acceleration remains unsolvable is presented and proved. By proving the proposition, it is also shown that some motion parameter ratios of target can be estimated under certain condition satisfied by measurements and time samples. The proposition is extended to arbitrary rank of manoeuvre for the observer and the target, which BOT remains unobservable property while the rank of target manoeuvre is higher than that of the observer manoeuvre. The theoretical analysis of this paper provides the guidelines for how the observer trajectory should be formulated to avoid unobservable state for BOT in practice application.
A 3-dimensional fracture generating scheme is presented which can be used to simulate water flow and contaminant (solute) transport through fracture system of a rock. It is presently limited to water saturated conditions, zero permeability for the rock matrix, and steady state water flow, but allows for transient solute transport. The scheme creates finite planar plates of uniform thickness which represent fractures in 3-dimensional space. A given fracture (plate) has the following descriptors: center location, orientation, shape, areal extent and aperture. Each parameter can be described by an appropriate probability distribution. Individual fractures are generated to form an assemblage of a certain fracture density. All fracture intersections and boundary/fracture intersections are determined and deadend fractures are eliminated. Flow through the fracture assemblage is considered laminar and described by Poiseuille's law. The principle of mass conservation at each intersection is used to develop the global matrix equation, which is solved subject to specified boundary conditions to yield the head and flow distribution at each intersection. Solute transport is considered to be advective between intersections with complete mixing at each intersection. Solutes added to the flow system can be explicitly followed and concentration vs. time relationships can be determined anywhere in the system. Some examples are included
A treatment method of displaying neutron flux distribution on the computer terminator with 3-dimensional stairs-appearance graph is described. Experiments show that this method and associated software written with BASIC are successful
无
2006-01-01
This article is concerned with second-order necessary and sufficient optimality conditions for optimal control problems governed by 3-dimensional Navier-Stokes equations. The periodic state constraint is considered.
Akay, Canan; Yaluğ, Suat
2015-01-01
Background The objective of this study was to investigate the stress distribution in the bone around zygomatic and dental implants for 3 different implant-retained obturator prostheses designs in a Aramany class IV maxillary defect using 3-dimensional finite element analysis (FEA). Material\\Methods A 3-dimensional finite element model of an Aramany class IV defect was created. Three different implant-retained obturator prostheses were modeled: model 1 with 1 zygomatic implant and 1 dental imp...
Metz, P. D.
A FORTRAN computer program called GROCS (GRound Coupled Systems) has been developed to study 3-dimensional underground heat flow. Features include the use of up to 30 finite elements or blocks of Earth which interact via finite difference heat flow equations and a subprogram which sets realistic time and depth dependent boundary conditions. No explicit consideration of mositure movement or freezing is given. GROCS has been used to model the thermal behavior of buried solar heat storage tanks (with and without insulation) and serpentine pipe fields for solar heat pump space conditioning systems. The program is available independently or in a form compatible with specially written TRNSYS component TYPE subroutines. The approach taken in the design of GROCS, the mathematics contained and the program architecture, are described. Then, the operation of the stand-alone version is explained. Finally, the validity of GROCS is discussed.
It is pointed out that large-scale vapor explosion may occur during a severe accident of a nuclear power plant. It is important to predict the possibility of the vapor explosion for the accident management of the nuclear power plant during a severe accident. In the present study, 3-dimensional 15-velocity model was developed based on the 2-dimensional 9-velocity model. This proposed model is applied to the numerical simulation of triggering of vapor explosion, i.e. vapor film collapse behavior by external force and droplet atomization. The objective of the present research is to validate the applicability of this model to simulate the triggering of vapor explosion compared with experimental data. (author)
Using 3-dimensional printing to create presurgical models for endodontic surgery.
Bahcall, James K
2014-09-01
Advances in endodontic surgery--from both a technological and procedural perspective-have been significant over the last 18 years. Although these technologies and procedural enhancements have significantly improved endodontic surgical treatment outcomes, there is still an ongoing challenge of overcoming the limitations of interpreting preoperative 2-dimensional (2-D) radiographic representation of a 3-dimensional (3-D) in vivo surgical field. Cone-beam Computed Tomography (CBCT) has helped to address this issue by providing a 3-D enhancement of the 2-D radiograph. The next logical step to further improve a presurgical case 3-D assessment is to create a surgical model from the CBCT scan. The purpose of this article is to introduce 3-D printing of CBCT scans for creating presurgical models for endodontic surgery. PMID:25197746
'3-Dimensional' TEM silicon-device analysis by combining plan-view and FIB sample preparation
Cross-sectional transmission electron microscopy (TEM) analysis has become routinely used in semiconductor industry to support failure and yield analysis. Plan-view transmission electron microscopy analysis however is much less frequently performed. In this paper it is illustrated that plan-view transmission electron microscopy analysis can add valuable information in yield analysis studies, especially when crystal defects are involved. '3-Dimensional' information can be obtained by combining cross-sectional transmission electron microscopy analysis with plan-view analysis. If the available material is limited, it can become a difficult choice whether to go for a cross-sectional or a plan-view analysis. Therefore it was explored if a cross-sectional specimen could still be made out of a plan-view specimen, using the plan-view analysis to locate the failure site precisely. This has recently been successfully done using the in-situ lift-out technique in the focused ion beam machine
Nakajima, Hiraku
2015-01-01
Consider the $3$-dimensional $\\mathcal N=4$ supersymmetric gauge theory associated with a compact Lie group $G$ and its quaternionic representation $\\mathbf M$. Physicists study its Coulomb branch, which is a noncompact hyper-K\\"ahler manifold, such as instanton moduli spaces on $\\mathbb R^4$, $SU(2)$-monopole moduli spaces on $\\mathbb R^3$, etc. In this paper and its sequel, we propose a mathematical definition of the coordinate ring of the Coulomb branch, using the vanishing cycle cohomology group of a certain moduli space for a gauged $\\sigma$-model on the $2$-sphere associated with $(G,\\mathbf M)$. In this first part, we check that the cohomology group has the correct graded dimensions expected from the monopole formula proposed by Cremonesi, Hanany and Zaffaroni arXiv:1309.2657. A ring structure (on the cohomology of a modified moduli space) will be introduced in the sequel of this paper.
UijtdeHaag, Maarten; Thomas, Robert; Rankin, James R.
2004-01-01
The report discusses the architecture and the flight test results of a 3-Dimensional Cockpit Display of Traffic and terrain Information (3D-CDTI). The presented 3D-CDTI is a perspective display format that combines existing Synthetic Vision System (SVS) research and Automatic Dependent Surveillance-Broadcast (ADS-B) technology to improve the pilot's situational awareness. The goal of the 3D-CDTI is to contribute to the development of new display concepts for NASA's Small Aircraft Transportation System research program. Papers were presented at the PLANS 2002 meeting and the ION-GPS 2002 meeting. The contents of this report are derived from the results discussed in those papers.
DIEP Flap Breast Reconstruction Using 3-dimensional Surface Imaging and a Printed Mold
Koichi Tomita, MD, PhD
2015-03-01
Full Text Available Summary: Recent advances in 3-dimensional (3D surface imaging technologies allow for digital quantification of complex breast tissue. We performed 11 unilateral breast reconstructions with deep inferior epigastric artery perforator (DIEP flaps (5 immediate, 6 delayed using 3D surface imaging for easier surgery planning and 3D-printed molds for shaping the breast neoparenchyma. A single- or double-pedicle flap was preoperatively planned according to the estimated tissue volume required and estimated total flap volume. The DIEP flap was then intraoperatively shaped with a 3D-printed mold that was based on a horizontally inverted shape of the contralateral breast. Cosmetic outcomes were assessed as satisfactory, as confirmed by the postoperative 3D measurements of bilateral breasts. We believe that DIEP flap reconstruction assisted with 3D surface imaging and a 3D-printed mold is a simple and quick method for rebuilding a symmetric breast.
DIEP Flap Breast Reconstruction Using 3-dimensional Surface Imaging and a Printed Mold.
Tomita, Koichi; Yano, Kenji; Hata, Yuki; Nishibayashi, Akimitsu; Hosokawa, Ko
2015-03-01
Recent advances in 3-dimensional (3D) surface imaging technologies allow for digital quantification of complex breast tissue. We performed 11 unilateral breast reconstructions with deep inferior epigastric artery perforator (DIEP) flaps (5 immediate, 6 delayed) using 3D surface imaging for easier surgery planning and 3D-printed molds for shaping the breast neoparenchyma. A single- or double-pedicle flap was preoperatively planned according to the estimated tissue volume required and estimated total flap volume. The DIEP flap was then intraoperatively shaped with a 3D-printed mold that was based on a horizontally inverted shape of the contralateral breast. Cosmetic outcomes were assessed as satisfactory, as confirmed by the postoperative 3D measurements of bilateral breasts. We believe that DIEP flap reconstruction assisted with 3D surface imaging and a 3D-printed mold is a simple and quick method for rebuilding a symmetric breast. PMID:25878927
Purpose: To investigate the applicability of 3-dimensional (3D) surface imaging for image guidance in deep-inspiration breath-hold radiation therapy (DIBH-RT) for patients with left-sided breast cancer. For this purpose, setup data based on captured 3D surfaces was compared with setup data based on cone beam computed tomography (CBCT). Methods and Materials: Twenty patients treated with DIBH-RT after breast-conserving surgery (BCS) were included. Before the start of treatment, each patient underwent a breath-hold CT scan for planning purposes. During treatment, dose delivery was preceded by setup verification using CBCT of the left breast. 3D surfaces were captured by a surface imaging system concurrently with the CBCT scan. Retrospectively, surface registrations were performed for CBCT to CT and for a captured 3D surface to CT. The resulting setup errors were compared with linear regression analysis. For the differences between setup errors, group mean, systematic error, random error, and 95% limits of agreement were calculated. Furthermore, receiver operating characteristic (ROC) analysis was performed. Results: Good correlation between setup errors was found: R2=0.70, 0.90, 0.82 in left-right, craniocaudal, and anterior-posterior directions, respectively. Systematic errors were ≤0.17 cm in all directions. Random errors were ≤0.15 cm. The limits of agreement were −0.34-0.48, −0.42-0.39, and −0.52-0.23 cm in left-right, craniocaudal, and anterior-posterior directions, respectively. ROC analysis showed that a threshold between 0.4 and 0.8 cm corresponds to promising true positive rates (0.78-0.95) and false positive rates (0.12-0.28). Conclusions: The results support the application of 3D surface imaging for image guidance in DIBH-RT after BCS.
Turbulence-induced vibration is an important concern in the design of the spacer grids of nuclear power plants. This study addresses numerically and statistically the effects of random pressures due to turbulent flows upon the fluctuating responses to the power spectrum density in one-dimensional nuclear fuel rod supported simply by the spacer grids. The dynamic forces produced by the pressure fluctuation on the rod surface are calculated by the 3-dimensional large eddy simulation turbulent model in Fluent-6 to simulate the flow field in the same as being measured empirically via pressure transducers. To acquire response to fluctuating pressure, the mode response equation of vibration is used in case of a cylindrical rod in one-dimensional case. The first modal longitudinal joint acceptance integral including a coherence function is also an important parameter affecting the displacement in the form of the root-mean-square of modal responses along with the damping ratio. The root mean square of the lateral displacement in addition to the natural frequency is studied using the power spectral density (PSD) and the longitudinal joint acceptance integral in a fundamental mode. The PSD random pressure on the middle point of the rod shows the typical turbulence pattern: the PSD energy decreases slightly in a low frequency region, but decreases rapidly and linearly with frequency as the frequency exceeds a certain value. The PSD in a very high frequency region is obtained assuming the slope is constant in a logarithmic graph after smoothing the PSD. It turns out that the root-mean-square of displacement ranges from 15 to 40 micro-meter at the maximum value using the mode response equation under the modal damping ratio ranging from 0.01 to 0.05. (authors)
A 60GHz-Band 3-Dimensional System-in-Package Transmitter Module with Integrated Antenna
Suematsu, Noriharu; Yoshida, Satoshi; Tanifuji, Shoichi; Kameda, Suguru; Takagi, Tadashi; Tsubouchi, Kazuo
A low cost, ultra small Radio Frequency (RF) transceiver module with integrated antenna is one of the key technologies for short range millimeter-wave wireless communication. This paper describes a 60GHz-band transmitter module with integrated dipole antenna. The module consists of three pieces of low-cost organic resin substrate. These substrates are vertically stacked by employing Cu ball bonding 3-dimensional (3-D) system-in-package (SiP) technology and the MMIC's are mounted on each organic substrates by using Au-stud bump bonding (SBB) technique. The planer dipole antenna is fabricated on the top of the stacked organic substrate to avoid the influence of the grounding metal on the base substrate. At 63GHz, maximum actual gain of 6.0dBi is obtained for fabricated planar dipole antenna. The measured radiation patterns are agreed with the electro-magnetic (EM) simulated result, therefore the other RF portion of the 3-D front-end module, such as flip chip mounted IC's on the top surface of the module, does not affect the antenna characteristics. The results show the feasibility of millimeter-wave low cost, ultra small antenna integrated module using stacked organic substrates.
Hierarchically mesoporous-macroporous-giant-porous bioactive glass/poly ε-caprolactone (PCL) composite scaffolds were prepared using a combination of the sol-gel method, evaporation-induced self-assembly process in the presence of nonionic triblock copolymer, EO100PO65EO100 (F127), as template, salt leaching method, and rapid prototyping techniques. F127 acts as a template, inducing the formation of mesopores, NaCl with sizes between 25 and 33 μm provides macro-pores after leaching, and rapid prototyping produces giant-pores. The structure and morphology of the scaffolds were characterized by the field emission scanning electron microscopy, transmission electron microscopy, and Hg porosimetry. The mechanical properties of the scaffolds were examined by the dynamic mechanical analysis. Their in vitro bioactivities were confirmed by immersing the scaffolds in simulated body fluid. Their biocompatibilities were also evaluated by culturing human bone marrow stromal cells on the scaffolds. The scaffolds show good molding capabilities, mechanical properties, 3 dimensionally well-interconnected pore structures, bioactivities, and biocompatibilities in vitro. Depending on the amount of NaCl, the scaffolds also show unique sponge-like properties, but still retain better mechanical properties than general salt leaching derived PCL scaffolds. All of the data provide good evidence that the obtained scaffolds possess excellent potential for applications in the fields of tissue engineering and drug storage.
ZHANG Jian-hui; XIA Qi-xiao; Bai Heng-jun; NING Hong-gang; ONUKI Akiyoshi
2006-01-01
The volume valve piezoelectric pump has received increasing attention from many areas because of its different characteristics such as the absence of chemical pollution and electromagnetic pollution.However,when the pump is working,it produces cavitations and the air bubbles that originate from these will flow out of the pump.Cavitations occurring in the pump will bring out noise and shorten the life of the pump.Furthermore,air bubbles flowing out of the pump will hinder its application in areas such as medical treatment and health care where blood transfusion and infusion are concerned.As a solution to this disadvantage,the CR3DMS (cavitations resistance with 3-dimensional mesh structure) method is developed,which is tested and verified to be effective on not only reducing the occurrence of cavitations and eliminating cavitations' flowing out,but also restraining the emission of noise.In conclusion,the pump with CR3DMS,on the relationship between flow and driving frequency and the relationship between flow and the number of Resistant-Layers in both theory and test,are analyzed.
Vehmeijer, Maarten; van Eijnatten, Maureen; Liberton, Niels; Wolff, Jan
2016-08-01
Fractures of the orbital floor are often a result of traffic accidents or interpersonal violence. To date, numerous materials and methods have been used to reconstruct the orbital floor. However, simple and cost-effective 3-dimensional (3D) printing technologies for the treatment of orbital floor fractures are still sought. This study describes a simple, precise, cost-effective method of treating orbital fractures using 3D printing technologies in combination with autologous bone. Enophthalmos and diplopia developed in a 64-year-old female patient with an orbital floor fracture. A virtual 3D model of the fracture site was generated from computed tomography images of the patient. The fracture was virtually closed using spline interpolation. Furthermore, a virtual individualized mold of the defect site was created, which was manufactured using an inkjet printer. The tangible mold was subsequently used during surgery to sculpture an individualized autologous orbital floor implant. Virtual reconstruction of the orbital floor and the resulting mold enhanced the overall accuracy and efficiency of the surgical procedure. The sculptured autologous orbital floor implant showed an excellent fit in vivo. The combination of virtual planning and 3D printing offers an accurate and cost-effective treatment method for orbital floor fractures. PMID:27137437
Optimal iodine dose for 3-dimensional multidetector-row CT angiography of the liver
Purpose: To clarify the optimal iodine dose of contrast material for 3-dimensional multidetector-row CT angiography (3D-MDCTA) of the venous vasculature of the liver using volume rendering technique. Materials and methods: This study included 103 patients who were randomly assigned to 5 contrast-enhanced MDCT protocol groups with different body-weight-tailored doses of contrast material: 500, 600, 630, 650, and 700 mgI/kg body weight. The arterial, portal, and hepatic parenchymal phases were obtained to evaluate enhancement values of the aorta, portal vein, and hepatic vein. Visualization of the portal and hepatic veins on the volume-rendering images of 3D-MDCTA was evaluated using a 5-point grade. Dunnett's test was used to compare the mean enhancement value and mean grades of image quality (700 mgI/kg dose group was control). Results: The mean enhancement values of portal and hepatic vein in the group with 500 and 600 mgI/kg were significantly lower than those of the control group. During visual assessment, a significantly lower mean grades were observed in 500 mgI/kg groups for the portal vein, and 500 and 600 mgI/kg groups for hepatic vein. There were no significant intergroup differences in mean enhancement values and visual assessment among the groups using 630 mgI/kg or more. Conclusion: Iodine doses of 630 mgI/kg was recommended for 3D-MDCTA
Automated image analysis reveals the dynamic 3-dimensional organization of multi-ciliary arrays
Domenico F. Galati
2016-01-01
Full Text Available Multi-ciliated cells (MCCs use polarized fields of undulating cilia (ciliary array to produce fluid flow that is essential for many biological processes. Cilia are positioned by microtubule scaffolds called basal bodies (BBs that are arranged within a spatially complex 3-dimensional geometry (3D. Here, we develop a robust and automated computational image analysis routine to quantify 3D BB organization in the ciliate, Tetrahymena thermophila. Using this routine, we generate the first morphologically constrained 3D reconstructions of Tetrahymena cells and elucidate rules that govern the kinetics of MCC organization. We demonstrate the interplay between BB duplication and cell size expansion through the cell cycle. In mutant cells, we identify a potential BB surveillance mechanism that balances large gaps in BB spacing by increasing the frequency of closely spaced BBs in other regions of the cell. Finally, by taking advantage of a mutant predisposed to BB disorganization, we locate the spatial domains that are most prone to disorganization by environmental stimuli. Collectively, our analyses reveal the importance of quantitative image analysis to understand the principles that guide the 3D organization of MCCs.
Desai, Ankit; Thomas, Raison; A. Baron, Tarunkumar; Shah, Rucha; Mehta, Dhoom-Singh
2015-01-01
Background The aim of the present study was to evaluate clinically and radiographically, the efficacy of immediate ridge augmentation to reconstruct the vertical and horizontal dimensions at extraction sites of periodontally hopeless tooth using an autogenous chin block graft. Material and Methods A total of 11 patients (7 male & 4 female) with localized advanced bone loss around single rooted teeth having hopeless prognosis and indicated for extraction were selected for the study. The teeth were atraumatically extracted and deficient sites were augmented using autogenous chin block graft. Parameters like clinically soft tissue height - width and also radiographic ridge height -width were measured before and 6 months after augmentation. Obtained results were tabulated and analysed statistically. Results After 6 months of immediate ridge augmentation, the mean gain in radiographic vertical height and horizontal width was 7.64 + 1.47 mm (P = 0.005) and 5.28 + 0.46 mm (P = 0.007) respectively which was found to be statistically significant (P extraction site. It can provide adequate hard and soft tissue foundation for perfect 3-Dimensional prosthetic positioning of implant in severely deficient ridges. Key words:Immediate ridge augmentation, periondontally hopeless tooth, autogenous chin graft, dental implant. PMID:26644832
3-dimensional conformal radiotherapy for cervical and upper-thoracic esophageal cancer
Objective: To evaluate the effect of 3-dimensional conformal radiotherapy (3D CRT) and prognostic factors for cervical and upper-thoracic esophageal cancer. Methods: Between July 1998 and July 2001, 33 patients with cervical and upper-thoracic esophageal cancer were treated with 3D CRT(2 Gy per day, 5 sessions a week to a total dose of 66-68 Gy over 6-7 weeks). Acute toxicities and survival rates were evaluated by Kaplan-Meier method and prognostic factors were analyzed by Cox proportional hazard model. Results: The 1-, 2-, 3-year local control rates were 87.9%, 75.8%, 45.5% respectively. The 1-, 2-, 3-year disease-free and overall survival rates were 72.7%, 60.6%, 30.3% and 78.8%, 66.8%, 44.2% respectively. GradeI- II acute esophagitis and bronchitis were the most common radiation side effects. Multivariate analysis revealed that the depth of primary tumor invasion, regional lymph node metastasis and tumor length were independent prognostic factors (P<0.05). Conclusions: 3D CRT can be considered as an effective and feasible approach to cervical and upper-thoracic esophageal cancer treatment. The depth of primary tumor invasion, regional lymph node status and tumor length are important prognostic indicators for cervical and upper-thoracic esophageal cancer. (authors)
Casting of 3-dimensional footwear prints in snow with foam blocks.
Petraco, Nicholas; Sherman, Hal; Dumitra, Aurora; Roberts, Marcel
2016-06-01
Commercially available foam blocks are presented as an alternative material for the casting and preservation of 3-dimensional footwear impressions located in snow. The method generates highly detailed foam casts of questioned footwear impressions. These casts can be compared to the known outsole standards made from the suspects' footwear. Modification of the commercially available foam casting blocks is simple and fast. The foam block is removed and a piece of cardboard is secured to one side of the block with painter's masking tape. The prepared foam block is then placed back into its original box, marked appropriately, closed and stored until needed. When required the foam block is carefully removed from its storage box and gently placed, foam side down, over the questioned footwear impression. Next, the crime scene technician's hands are placed on top of the cardboard and pressure is gently applied by firmly pressing down onto the impression. The foam cast is removed, dried and placed back into its original container and sealed. The resulting 3D impressions can be directly compared to the outsole of known suspected item(s) of footwear. PMID:27124876
SBNCT plan: A 3-dimensional treatment planning system for boron neutron capture therapy
The need for accurate and comprehensive 3-dimensional treatment planning for boron neutron capture therapy (BNCT) has been debated for the past several years. Although many argue against the need for elaborate and expensive treatment planning programs which mimic conventional radiotherapy planning systems, it is clear that in order to realize significant gains over conventional fractionated radiation therapy, patients must be treated to the edge of normal tissue tolerance. Just how close to this edge is dictated by the uncertainties in dosimetry. Hence the focus of BNCT planning is the determination of dose distribution throughout normal tissue volumes. Although precise geometric manipulation of the epithermal neutron beam is not achievable, the following variables play an important role in BNCT optimization: patient orientation, dose fractionation, number of fields, megawatt-minutes per fraction, use of surface bolus, and use of collimation. Other variables which are not as easily adjustable and would not, therefore, be part of treatment planning optimization, include external patient contour, internal patient heterogeneities, boron compound distributions, and RBE's. The boron neutron capture therapy planning system developed at SUNY Stony Brook (SBNCT-Plan) was designed as an interactive graphic tool to assist the radiation oncologist in generating the optimum plan for a neutron capture treatment
An experimental study for qualitatively diagnosing stapes lesions by helical 3-dimensional CT
Kawaue, Akifumi; Kuki, Kiyonori; Yamanaka, Noboru [Wakayama Medical Univ., Wakayama (Japan); Nishimura, Michihiko
2001-08-01
To evaluate qualitative diagnosis of stapes lesions by 3-dimensional computed tomography (3D-CT) combined with superselective image processing (3D-SS) of stapes, we studied helical 3D-CT on a phantom model of the temporal bone. Two stapes models were used-1 made from the bone filler, Celatite, consistent in bone density but changing in cross sectional area, and the other made from an apacerum rod used in quantitative computed tomography (QCT), consistent in cross sectional area but changing in bone density. These stapes models were put into a skull phantom and analyzed by helical 3D-CT. The influence of the tympanic cavity conditions on CT images of stapes was evaluated by filling the phantom model with Vaseline following 3D selective reconstruction. In all stapes models, lowering the lower CT window width threshold resulted in an enlarged cross-sectional area of the model. The higher the bone density, the lower the increase in cross-sectional area in the image. The stapes model with lower density had greater influence on the imaging by tympanic cavity conditions and was likely to be misdiagnosed as showing higher bone density. Based on the experimental study, 3D-SS by helical 3D-CT appears to be a useful measure for qualitatively diagnosing stapes lesions. (author)
Development of a 3-Dimensional Dosimetry System for Leksell Gamma Knife-Perfexion
Yoon, KyoungJun; Lee, DoHeui; Cho, ByungChul; Lee, SangWook; Ahn, SeungDo
2015-01-01
The purpose of our study is to develop a new, 3-dimensional dosimetry system to verify the accuracy of dose deliveries in Leksell Gamma Knife-Perfexion TM (LGKP) (Elekta, Norcross, GA, USA). The instrument consists of a moving head phantom, an embedded thin active layer and a CCD camera system and was designed to be mounted to LGKP. As an active material concentrically located in the hemispheric head phantom, we choose Gafchromic EBT3 films and Gd2O2S;Tb phosphor sheets for dosimetric measurements. Also, to compensate the lack of backscatter, we located a 1 cm thick PMMA plate downstream of the active layer. The PMMA plate was transparent for scintillation lights to reach the CCD with 1200x1200 pixels by a 5.2 um pitch. Using this system, three hundred images by a 0.2 mm slice gap were acquired under each of three collimator setups, i.e. 4 mm, 8 mm, and 16 mm, respectively. The 2D projected images taken by CCD camera were compared with the dose distributions measured by EBT3 films in the same conditions. All ...
Grosse, Jirka; Wehland, Markus; Pietsch, Jessica; Schulz, Herbert; Saar, Katrin; Hübner, Norbert; Eilles, Christoph; Bauer, Johann; Abou-El-Ardat, Khalil; Baatout, Sarah; Ma, Xiao; Infanger, Manfred; Hemmersbach, Ruth; Grimm, Daniela
2012-12-01
This study focused on the effects induced by a random positioning machine (RPM) on FTC-133 thyroid cancer cells and evaluated signaling elements involved in 3-dimensional multicellular tumor spheroid (MCTS) formation. The cells were cultured on the RPM, a device developed to simulate microgravity, and under static 1-g conditions. After 24 h on the RPM, MCTSs swimming in culture supernatants were found, in addition to growth of adherent (AD) cells. Cells grown on the RPM showed higher levels of NF-κB p65 protein and apoptosis than 1-g controls, a result also found earlier in endothelial cells. Employing microarray analysis, we found 487 significantly regulated transcripts belonging not only to the apoptosis pathway but also to other biological processes. Selected transcripts were analyzed with quantitative real-time PCR using the same samples. Compared with 1-g IL-6, IL-8, CD44, and OPN were significantly up-regulated in AD cells but not in MCTSs, while ERK1/2, CAV2, TLN1, and CTGF were significantly down-regulated in AD cells. Simultaneously, the expression of ERK2, IL-6, CAV2, TLN1, and CTGF was reduced in MCTSs. IL-6 protein expression and secretion mirrored its gene expression. Thus, we concluded that the signaling elements IL-6, IL-8, OPN, TLN1, and CTGF are involved with NF-κB p65 in RPM-dependent thyroid carcinoma cell spheroid formation. PMID:22964303
David G Barnes
Full Text Available With the latest release of the S2PLOT graphics library, embedding interactive, 3-dimensional (3-d scientific figures in Adobe Portable Document Format (PDF files is simple, and can be accomplished without commercial software. In this paper, we motivate the need for embedding 3-d figures in scholarly articles. We explain how 3-d figures can be created using the S2PLOT graphics library, exported to Product Representation Compact (PRC format, and included as fully interactive, 3-d figures in PDF files using the movie15 LaTeX package. We present new examples of 3-d PDF figures, explain how they have been made, validate them, and comment on their advantages over traditional, static 2-dimensional (2-d figures. With the judicious use of 3-d rather than 2-d figures, scientists can now publish, share and archive more useful, flexible and faithful representations of their study outcomes. The article you are reading does not have embedded 3-d figures. The full paper, with embedded 3-d figures, is recommended and is available as a supplementary download from PLoS ONE (File S2.
Vivian M. Hsu, MD
2014-09-01
Conclusions: This pilot study illustrates that the face can be objectively and quantitatively evaluated using dynamic major strain analysis. The technology of 3-dimensional optical imaging can be used to advance our understanding of facial soft-tissue dynamics and the effects of animation on facial strain over time.
Shearing, P.R.; Howard, L.E.; Jørgensen, Peter Stanley; Brandon, N.P.; Harris, S.J.
2010-01-01
The 3-dimensional microstructure of a porous electrode from a lithium-ion battery has been characterized for the first time. We use X-ray tomography to reconstruct a 43 × 348 × 478 μm sample volume with voxel dimensions of 480 nm, subsequent division of the reconstructed volumes into sub-volumes of...
The accuracy of reformatted images using a new virtual 3-dimensional dental implant system
Choi, Jin Seok; Kim, Eun Kyung; Han, Won Jeong [Dankook University College of Medicine, Seoul (Korea, Republic of)
2003-09-15
To compare the measurements of the mandible and the detectability of the mandibular canal on reformatted images using a newly developed 3-dimensional implant simulation program with traditionally used CT multiplanar reconstruction program and true measurements. Ten dry dog mandibles were used in this study. Occlusal templates for CT examination were fabricated and marked with gutta percha at ten sites. Axial CT scans were taken and reconstructed using DentaScan (D group) and Vimplant program (V group), and each mandible was sectioned at the previously marked sites (R group). Maximum vertical height (H) and maximum width (W) of the mandible, the distances from buccal border of the mandibular canal to the most buccal aspect of the mandible (X), and the distance from the superior border of the mandibular canal to the alveolar crest (Y) were measured, and the mandibular measurements in each group were compared. Detectability of mandibular canal was evaluated using a 3-point scale in both V and D groups by three oral radiologists and compared. H in the V group was slightly greater than that in the D group, and W and X in the V group was slightly less than those in the D group. H in the V group was less than that in the R group, and W and X in the V group was larger than those in the R group. The detectability of the mandibular canal did not show statistically significant differences between V and D groups. The results of the experiment show that the newly developed, inexpensive Vimplant simulation program can be used as an alternative to the traditionally used, and more expensive CT multiplanar reconstruction program.
A customized bolus produced using a 3-dimensional printer for radiotherapy.
Shin-Wook Kim
Full Text Available OBJECTIVE: Boluses are used in high-energy radiotherapy in order to overcome the skin sparing effect. In practice though, commonly used flat boluses fail to make a perfect contact with the irregular surface of the patient's skin, resulting in air gaps. Hence, we fabricated a customized bolus using a 3-dimensional (3D printer and evaluated its feasibility for radiotherapy. METHODS: We designed two kinds of bolus for production on a 3D printer, one of which was the 3D printed flat bolus for the Blue water phantom and the other was a 3D printed customized bolus for the RANDO phantom. The 3D printed flat bolus was fabricated to verify its physical quality. The resulting 3D printed flat bolus was evaluated by assessing dosimetric parameters such as D1.5 cm, D5 cm, and D10 cm. The 3D printed customized bolus was then fabricated, and its quality and clinical feasibility were evaluated by visual inspection and by assessing dosimetric parameters such as Dmax, Dmin, Dmean, D90%, and V90%. RESULTS: The dosimetric parameters of the resulting 3D printed flat bolus showed that it was a useful dose escalating material, equivalent to a commercially available flat bolus. Analysis of the dosimetric parameters of the 3D printed customized bolus demonstrated that it is provided good dose escalation and good contact with the irregular surface of the RANDO phantom. CONCLUSIONS: A customized bolus produced using a 3D printer could potentially replace commercially available flat boluses.
This study is to evaluate the xerostomia following 3-dimensional conformal radiation therapy (3D CRT) in nasopharynx cancer patients using the xerostomia questionnaire score (XQS). Questionnaire study was done on 51 patients with nasopharynx cancer who received 3D CRT from Dec. 2000 to Aug. 2005. 3D CRT technique is based on 'serial shrinking field' concept by 3 times of computed tomography (CT) simulation. Total target dose to the primary tumor was 72 Gy with 1.8 Gy daily fractions. Xerostomia was assessed with 4-questions XQS, and the associations between XQS and time elapsed after RT, age, sex, stage, concurrent chemotherapy, an parotid dose were analyzed. Concurrent chemotherapy was given to 40 patients and RT alone was given to 11 patients. The median time elapsed after 3D CRT was 20 (1 ∼ 58) months and the mean XQS of all 51 patients was 8.4 ± 1.9 (6 ∼ 14). XQS continuously and significantly decreased over time after 3D CRT (χ 2 -0.484, ρ < 0.05). There was no significant difference in XQS according to sex, age, and stag. However, XQS of concurrent chemotherapy patients was significantly higher than RT alone patients (ρ = 0.001). XQS of patients receiving total mean parotid dose ≥ 35 Gy was significantly higher than < 35 Gy (ρ = 0.05). Decreasing tendency of XQS over time after 3D CRT was observed. Concurrent chemotherapy and total mean parotid dose ≥ 35 Gy were suggested to adversely affect radiation-induced xerostomia
Albedo and heat transport in 3-dimensional model simulations of the early Archean climate
H. Kienert
2013-01-01
Full Text Available At the beginning of the Archean eon (ca. 3.8 billion yr ago, the Earth's climate state was significantly different from today due to the lower solar luminosity, smaller continental fraction, higher rotation rate and, presumably, significantly larger greenhouse gas concentrations. All these aspects play a role in solutions to the "faint young Sun problem" which must explain why the ocean surface was not fully frozen at that time. Here, we present 3-dimensional model simulations of climate states that are consistent with early Archean boundary conditions and have different CO_{2} concentrations, aiming at an understanding of the fundamental characteristics of the early Archean climate system. We focus on three states: one of them is ice-free, one has the same mean surface air temperature of 288 K as today's Earth and the third one is the coldest stable state in which there is still an area with liquid surface water (i.e. the critical state at the transition to a "snowball Earth". We find a reduction in meridional heat transport compared to today which leads to a steeper latitudinal temperature profile and has atmospheric as well as oceanic contributions. Ocean surface velocities are largely zonal, and the strength of the atmospheric meridional circulation is significantly reduced in all three states. These aspects contribute to the observed relation between global mean temperature and albedo, which we suggest as a parameterisation of the ice-albedo feedback for 1-dimensional model simulations of the early Archean and thus the faint young Sun problem.
Development of a 3-dimensional dosimetry system for Leksell Gamma Knife Perfexion
Yoon, KyoungJun; Kwak, JungWon; Lee, DoHeui; Cho, ByungChul; Lee, SangWook; Ahn, SeungDo
2015-07-01
The purpose of our study is to develop a new, 3-dimensional dosimetry system to verify the accuracy of dose deliveries in Leksell Gamma Knife Perfexion (LGKP) (Elekta, Norcross, GA, USA). The instrument consists of a moving head phantom, an embedded thin active layer and a CCD camera system and was designed to be mounted to LGKP. As an active material concentrically located in the hemispheric head phantom, we choose Gafchromic EBT3 films and Gd2O2S:Tb phosphor sheets for dosimetric measurements. Also, to compensate for the lack of backscatter, we located a 1-cm-thick poly methyl methacrylate (PMMA) plate downstream of the active layer. The PMMA plate was transparent to scintillation light to reach the CCD with 1200 × 1200 pixels and a 5.2 µm pitch. With this system, 300 images with a 0.2-mm slice gap were acquired under each of three collimator setups, i.e. 4-mm, 8-mm, and 16-mm, respectively. The 2D projected images taken by the CCD camera were compared with the dose distributions measured by the EBT3 films under the same conditions. All 2D distributions were normalized to the maximum values derived by fitting peaks for each collimator setup. The differences in the full widths at half maximum (FWHM) of 2D profiles between CCD images and film doses were measured to be less than 0.3-mm. The scanning task for all peak regions took less than three minutes with the new instrument. So it can be utilized as a QA tool for the Gamma knife radiosurgery system instead of film dosimetry, the use of which requires much more time and many more resources.
SU-E-T-104: Development of 3 Dimensional Dosimetry System for Gamma Knife
Yoon, K; Kwak, J; Cho, B; Lee, D; Ahn, S [Asan Medical Center, Seoul (Korea, Republic of)
2014-06-01
Purpose: The aim of this study was to develop a new 3 dimensional dosimetry system to verify the dosimetric accuracy of Leksell Gamma Knife-Perfexion™ (LGK) (Elekta, Norcross, GA). Methods: We designed and manufactured a lightweight dosimetry instrument to be equipped with the head frame to LGK. It consists of a head phantom, a scintillator, a CCD camera and a step motor. The 10×10 cm2 sheet of Gd2O3;Tb phosphor or Gafchromic EBT3 film was located at the center of the 16 cm diameter hemispherical PMMA, the head phantom. The additional backscatter compensating material of 1 cm thick PMMA plate was placed downstream of the phosphor sheet. The backscatter plate was transparent for scintillation lights to reach the CCD camera with 1200×1200 pixels by 5.2 um pitch. With This equipment, 300 images with 0.2 mm of slice gap were acquired under three collimator setups (4mm, 8mm and 16mm), respectively. The 2D projected doses from 3D distributions were compared with the exposured film dose. Results: As all doses normalized by the maximum dose value in 16 mm setup, the relative differences between the equipment dose and film dose were 0.2% for 4mm collimator and 0.5% for 8mm. The acquisition of 300 images by the equipment took less than 3 minutes. Conclusion: The new equipment was verified to be a good substitute to radiochromic film, with which required more time and resources. Especially, the new methods was considered to provide much convenient and faster solution in the 3D dose acquisition for LGK.
The accuracy of reformatted images using a new virtual 3-dimensional dental implant system
To compare the measurements of the mandible and the detectability of the mandibular canal on reformatted images using a newly developed 3-dimensional implant simulation program with traditionally used CT multiplanar reconstruction program and true measurements. Ten dry dog mandibles were used in this study. Occlusal templates for CT examination were fabricated and marked with gutta percha at ten sites. Axial CT scans were taken and reconstructed using DentaScan (D group) and Vimplant program (V group), and each mandible was sectioned at the previously marked sites (R group). Maximum vertical height (H) and maximum width (W) of the mandible, the distances from buccal border of the mandibular canal to the most buccal aspect of the mandible (X), and the distance from the superior border of the mandibular canal to the alveolar crest (Y) were measured, and the mandibular measurements in each group were compared. Detectability of mandibular canal was evaluated using a 3-point scale in both V and D groups by three oral radiologists and compared. H in the V group was slightly greater than that in the D group, and W and X in the V group was slightly less than those in the D group. H in the V group was less than that in the R group, and W and X in the V group was larger than those in the R group. The detectability of the mandibular canal did not show statistically significant differences between V and D groups. The results of the experiment show that the newly developed, inexpensive Vimplant simulation program can be used as an alternative to the traditionally used, and more expensive CT multiplanar reconstruction program.
Oxidation behavior of ammonium in a 3-dimensional biofilm-electrode reactor.
Tang, Jinjing; Guo, Jinsong; Fang, Fang; Chen, Youpeng; Lei, Lijing; Yang, Lin
2013-12-01
Excess nitrogenous compounds are detrimental to natural water systems and to human health. To completely realize autohydrogenotrophic nitrogen removal, a novel 3-dimensional biofilm-electrode reactor was designed. Titanium was electroplated with ruthenium and used as the anode. Activated carbon fiber felt was used as the cathode. The reactor was separated into two chambers by a permeable membrane. The cathode chamber was filled with granular graphite and glass beads. The cathode and cathode chamber were inhabited with domesticated biofilm. In the absence of organic substances, a nitrogen removal efficiency of up to 91% was achieved at DO levels of 3.42 +/- 0.37 mg/L when the applied current density was only 0.02 mA/cm2. The oxidation of ammonium in biofilm-electrode reactors was also investigated. It was found that ammonium could be oxidized not only on the anode but also on particle electrodes in the cathode chamber of the biofilm-electrode reactor. Oxidation rates of ammonium and nitrogen removal efficiency were found to be affected by the electric current loading on the biofilm-electrode reactor. The kinetic model of ammonium at different electric currents was analyzed by a first-order reaction kinetics equation. The regression analysis implied that when the current density was less than 0.02 mA/cm2, ammonium removal was positively correlated to the current density. However, when the current density was more than 0.02 mA/cm2, the electric current became a limiting factor for the oxidation rate of ammonium and nitrogen removal efficiency. PMID:24649670
Estimating the costs of intensity-modulated and 3-dimensional conformal radiotherapy in Ontario
Yong, J.H.E.; McGowan, T.; Redmond-Misner, R.; Beca, J.; Warde, P.; Gutierrez, E.; Hoch, J.S.
2016-01-01
Background Radiotherapy is a common treatment for many cancers, but up-to-date estimates of the costs of radiotherapy are lacking. In the present study, we estimated the unit costs of intensity-modulated radiotherapy (imrt) and 3-dimensional conformal radiotherapy (3D-crt) in Ontario. Methods An activity-based costing model was developed to estimate the costs of imrt and 3D-crt in prostate cancer. It included the costs of equipment, staff, and supporting infrastructure. The framework was subsequently adapted to estimate the costs of radiotherapy in breast cancer and head-and-neck cancer. We also tested various scenarios by varying the program maturity and the use of volumetric modulated arc therapy (vmat) alongside imrt. Results From the perspective of the health care system, treating prostate cancer with imrt and 3D-crt respectively cost $12,834 and $12,453 per patient. The cost of radiotherapy ranged from $5,270 to $14,155 and was sensitive to analytic perspective, radiation technique, and disease site. Cases of head-and-neck cancer were the most costly, being driven by treatment complexity and fractions per treatment. Although imrt was more costly than 3D-crt, its cost will likely decline over time as programs mature and vmat is incorporated. Conclusions Our costing model can be modified to estimate the costs of 3D-crt and imrt for various disease sites and settings. The results demonstrate the important role of capital costs in studies of radiotherapy cost from a health system perspective, which our model can accommodate. In addition, our study established the need for future analyses of imrt cost to consider how vmat affects time consumption.
Purpose: To assess the new method of 3-dimensional echocardiography in comparison to the 'gold standard' MRI as to its ability to calculate left ventricular volumes in patients with congenital heart disease. Materials and methods: Eighteen patients between the ages of 3.9 to 37.3 years (mean: 12.8±9.7) with a geometrically abnormal left ventricle were examined using a 1.5 T scanner with a fast gradient-echo sequence (TR=14 ms, TE=2.6-2.9 ms, FOV=300-400 mm, flip angle=20 , matrix=128:256, slice thickness=5 mm, retrospective gating) in multislice-multiphase technique. Transthoracic 3D-echocardiography was performed with a 3.5 MHz transducer and a Tomtec trademark (Munich, Germany) system for 3D reconstruction. Results: Volume calculation was possible in all patients with 3D-echocardiography, but the muscle mass calculation only succeeded in 11 to 18 patients (61%) due to inadequate visualization of the entire myocardium. Comparing MRI and 3D-echocardiography, the correlation was r=0.97 for the end-systolic volumes, r=0.98 for the end-diastolic volumes, r=0.79 for the end-systolic muscle mass and r=0.77 for the end-diastolic muscle mass. The agreement between both methods was considered good for the calculated end-diastolic volumes and sufficient for the calculated end-systolic volumes. The muscle mass calculations showed larger differences especially for the end-systolic mass. Mean intraobserver variability was 18.6% for end-systolic and 8.3% for end-diastolic volumes. Conclusion: In patients with an abnormal left ventricular configuration due to congenital heart disease, the new method of 3D-echocardiography is sufficient for volume calculations in preselected patients. The high intraobserver variability is still a limitation of transthoracic 3D-echocardiography in comparison to MRI. (orig.)
Dose distributions of nominal 6 and 18 MV x-ray beams and cobalt-60 photon beams were modelled in three dimensions in heterogeneous phantoms using convolutions that employ the fast Fourier transform. Doses were computed at 65 536 calculation points (i.e. a 64x64x16 matrix) for five spectral components. Primary fluence was calculated by ray-tracing through the inhomogeneous medium. Dose was obtained by convolution with the primary fluence. The primary dose component, mediated by electrons, was calculated separately from the scatter component, mediated by scattered x-rays. The calculation time was approximately 3 minutes per spectral component on a Digital Equipment Corporation VAXstation 3500. Comparisons of FFT convolution calculations with measurements showed that an FFT convolution algorithm can predict most of the characteristics of an x-ray beam passing through a heterogeneous phantom. (author)
Investigation on the Thermal Conductivity of 3-Dimensional and 4-Directional Braided Composites
Liu Zhenguo; Zhang Haiguo; Lu Zixing; Li Diansen
2007-01-01
It is vital to choose a factual and reasonable micro-structural model of braided composites for improving the calculating precision of thermal property of 3-D braided composites by finite element method (FEM). On the basis of new microstructure model of braided composites proposed recently, the model of FEM calculation for thermal conductivity of 3-dimennsional and 4-directional braided composites is set up in this paper. The curves of coefficient of effective thermal conductivity versus fiber volume ratio and interior braiding angle are obtained. Furthermore, comparing the results of FEM with the available experimental data, the reasonability and veracity of calculation are confirmed at the same time.
Titan global climate model: A new 3-dimensional version of the IPSL Titan GCM
Lebonnois, Sébastien; Burgalat, Jérémie; Rannou, Pascal; Charnay, Benjamin
2012-03-01
We have developed a new 3-dimensional climate model for Titan’s atmosphere, using the physics of the IPSL Titan 2-dimensional climate model with the current version of the LMDZ General Circulation Model dynamical core. Microphysics and photochemistry are still computed as zonal averages. This GCM covers altitudes from surface to 500 km altitude, with barotropic waves now being resolved and the diurnal cycle included. The boundary layer scheme has been changed, yielding a strong improvement in the tropospheric zonal wind profile modeled at Huygens descent position and season. The potential temperature profile is fairly consistent with Huygens observations in the lowest 10 km. The latitudinal profile of the near-surface temperature is close to observed values. The minimum of zonal wind observed by the Huygens probe just above the tropopause is also present in these simulations, and its origin is discussed by comparing solar heating and dynamical transport of energy. The stratospheric temperature and wind fields are consistent with our previous works. Compared to observations, the zonal wind peak is too weak (around 120 m/s) and too low (around 200 km). The temperature structures appear to be compressed in altitude, and depart strongly from observations in the upper stratosphere. These discrepancies are correlated, and most probably related to the altitude of the haze production. The model produces a detached haze layer located more than 150 km lower than observed by the Cassini instruments. This low production altitude is due to the current position of the GCM upper boundary. However, the temporal behaviour of the detached haze layer in the model may explain the seasonal differences observed between Cassini and Voyager 1. The waves present in the GCM are analyzed, together with their respective roles in the angular momentum budget. Though the role of the mean meridional circulation in momentum transport is similar to previous work, and the transport by barotropic
Goodall, Nicola; Kisiswa, Lilian; Prashar, Ankush; Faulkner, Stuart; Tokarczuk, Paweł; Singh, Krish; Erichsen, Jonathan T; Guggenheim, Jez; Halfter, Willi; Wride, Michael A
2009-10-01
Magnetic resonance imaging (MRI) is a powerful tool for generating 3-dimensional structural and functional image data. MRI has already proven valuable in creating atlases of mouse and quail development. Here, we have exploited high resolution MRI to determine the parameters necessary to acquire images of the chick embryo eye. Using a 9.4 Tesla (400 MHz) high field ultra-shielded and refrigerated magnet (Bruker), MRI was carried out on paraformaldehyde-fixed chick embryos or heads at E4, E6, E8, and E10. Image data were processed using established and custom packages (MRICro, ImageJ, ParaVision, Bruker and mri3dX). Voxel dimensions ranged from 62.5 microm to 117.2 microm. We subsequently used the images obtained from the MRI data in order to make precise measurements of chick embryo eye surface area, volume and axial length from E4 to E10. MRI was validated for accurate sizing of ocular tissue features by direct comparison with previously published literature. Furthermore, we demonstrate the utility of high resolution MRI for making accurate measurements of morphological changes due to experimental manipulation of chick eye development, thereby facilitating a better understanding of the effects on chick embryo eye development and growth of such manipulations. Chondroitin sulphate or heparin were microinjected into the vitreous cavity of the right eyes of each of 3 embryos at E5. At E10, embryos were fixed and various eye parameters (volume, surface area, axial length and equatorial diameter) were determined using MRI and normalised with respect to the un-injected left eyes. Statistically significant alterations in eye volume (p < 0.05; increases with chondroitin sulphate and decreases with heparin) and changes in vitreous homogeneity were observed in embryos following microinjection of glycosaminoglycans. Furthermore, in the heparin-injected eyes, significant disturbances at the vitreo-retinal boundary were observed as well as retinal folding and detachment
Brand, Jefferson C
2016-01-01
No single-image magnetic resonance imaging (MRI) assessment-Goutallier classification, Fuchs classification, or cross-sectional area-is predictive of whole-muscle volume or fatty atrophy of the supraspinatus or infraspinatus. Rather, 3-dimensional MRI measurement of whole-muscle volume and fat-free muscle volume is required and is associated with shoulder strength, which is clinically relevant. Three-dimensional MRI may represent a new gold standard for assessment of the rotator cuff musculature using imaging and may help to predict the feasibility of repair of a rotator cuff tear as well as the postoperative outcome. Unfortunately, 3-dimensional MRI assessment of muscle volume is labor intensive and is not widely available for clinical use. PMID:26743416
WANG Yan-long; MAO Ming; LU Yi-ping; BIE Jie-min
2005-01-01
Probes into a new and effective method in arranging the powerhouses of tank & armored vehicles. Theory and method of 3-dimensional rectangular packing are adapted to arrange effectively almost all the systems and components in the powerhouse of the vehicle, thus the study can be regarded as an attempt for the theory's engineering applications in the field of tank & armored vehicle design. It is proved that most parts of the solutions attained are reasonable, and some of the solutions are innovative.
Martin R. Brown
2010-01-01
Full Text Available The evolution of echocardiography from 2-Dimensional Transthoracic Echo through to real time 3-Dimensional Transoesophageal Echo has enabled more accurate visualisation and quantification of valvular disorders especially prosthetic mitral valve paravalvular regurgitation. However, validation of accuracy is rarely confirmed by surgical or post-mortem specimens. We present a case directly comparing different echocardiographic modality images to post mortem specimens in a patient with prosthetic mitral valve paravalvular regurgitation.
Yanlong Tai; Gilles Lubineau
2016-01-01
Recently, flexible and transparent conductive films (TCFs) are drawing more attention for their central role in future applications of flexible electronics. Here, we report the controllable fabrication of TCFs for moisture-sensing applications based on heating-rate-triggered, 3-dimensional porous conducting networks through drop casting lithography of single-walled carbon nanotube (SWCNT)/poly(3,4-ethylenedioxythiophene)-polystyrene sulfonate (PEDOT:PSS) ink. How ink formula and baking condit...
Preparation of 1-3 Dimensional PZT-NFO Nanocomposite Films by Off-axis Magnetron Sputtering
ZHANG Hui, MA Yong-Jun, WANG Yi-Cheng, WEN Dan-Dan, YE Fei, BAI Fei-Ming
2014-04-01
Full Text Available Self-assembled nanocomposite Pb(Zr0.52Ti0.48O3-NiFe2O4 films were prepared on the (001-oriented MgAl2O4 substrates by a 90° off-axis magnetron sputtering method. The influences of substrate temperature, argon over oxygen ratio and sputtering power on the structure and properties of PZT-NFO nanocomposite films were studied. The optimal growth conditions are substrate temperature of 800 °C, argon over oxygen ratio of 1:1 and sputtering power of 160 W. XRD studies reveal that the PZT-NFO film is epitaxial along both the in-plane and out-of-plane directions, and the vertical lattice mismatch between the PZT phase and the NFO phase is very small. AFM and SEM analysis show that the PZT-NFO films have clear 1-3 dimensional nanocomposite structure, and the diameter of NFO nanorods is 80-150 nm. Further decreasing argon over oxygen ratio is beneficial for the formation of NFO. However, increasing RF power causes a transition from an 1-3 dimensional nanocomposite to a 0-3 dimensional chaotic structure. Magnetic measurement shows that the saturation magnetization of NFO phase is 120-160 kA/m, lower than that of bulk NFO phase, possibly due to the interfacial diffusion between the NFO and the PZT phases.
Bonatsos, Dennis; Lenis, D; Raychev, P P; Roussev, R P; Terziev, P A
2000-01-01
Magic numbers predicted by a 3-dimensional q-deformed harmonic oscillator with Uq(3)>SOq(3) symmetry are compared to experimental data for atomic clusters of alkali metals (Li, Na, K, Rb, Cs), noble metals (Cu, Ag, Au), divalent metals (Zn, Cd), and trivalent metals (Al, In), as well as to theoretical predictions of jellium models, Woods-Saxon and wine bottle potentials, and to the classification scheme using the 3n+l pseudo quantum number. In alkali metal clusters and noble metal clusters the 3-dimensional q-deformed harmonic oscillator correctly predicts all experimentally observed magic numbers up to 1500 (which is the expected limit of validity for theories based on the filling of electronic shells), while in addition it gives satisfactory results for the magic numbers of clusters of divalent metals and trivalent metals, thus indicating that Uq(3), which is a nonlinear extension of the U(3) symmetry of the spherical (3-dimensional isotropic) harmonic oscillator, is a good candidate for being the symmetry ...
Paul Bracken
2010-01-01
The moving frame and associated Gauss-Codazzi equations for surfaces in Minkowski three space are introduced. A split-quaternionic representation is used to identify the Gauss-Weingarten equations with a Lax pair representation. This Lax pair representaion is calculated and given explicitly.
Further validation and development of the 3-dimensional dynamics code TRAB-3D
TRAB-3D, the newest member of VTT's code system for LWR dynamics calculations, is a coupled neutronics-thermal hydraulics code for transient and accident analyses of BWR reactors. The code is largely based on the ID code TRAB and the 3D hexagonal code HEXTRAN which have long been used in safety analyses of Finnish and foreign reactors. In TRAB-3D the two-group neutron diffusion equations are solved in three dimensions in a rectangular fuel assembly geometry by a new method which is similar to the nodal expansion method developed earlier at VTT for hexagonal geometry. The accuracy of the method is shown by comparison with 2D fine-mesh calculations and with 3D calculation for the Olkiluoto reactor with the POLCA-4 code. Capabilities of the code in dynamic analyses is validated with the OECD/NEA LWR benchmark problems and with transient calculations for the Olkiluoto reactor. Further development of the code includes a pin power reconstruction method which makes use of precomputed power distributions within fuel assemblies
Paul Bracken
2010-01-01
Full Text Available The moving frame and associated Gauss-Codazzi equations for surfaces in Minkowski three space are introduced. A split-quaternionic representation is used to identify the Gauss-Weingarten equations with a Lax pair representation. This Lax pair representaion is calculated and given explicitly.
SUSD3D, 1-, 2-, 3-Dimensional Cross Section Sensitivity and Uncertainty Code
1 - Description of program or function: SUSD3D calculates sensitivity coefficients and standard deviation in the calculated detector responses or design parameters of interest due to input cross sections and their uncertainties. One-, two- and three-dimensional transport problems can be studied. Several types of uncertainties can be considered, i.e. those due to: (1) neutron/gamma multigroup cross sections, (2) energy-dependent response functions, (3) secondary angular distribution (SAD) or secondary energy distribution (SED) uncertainties. SUSD3D development was started from the SUSD [6] code. Besides several minor modifications and extensions SUSD3D differs from SUSD in particular that: - Three-dimensional analysis is possible, - Flux moment files are used to evaluate the sensitivity profiles, instead of angular flux files; substantially reducing in this was the computer space requirements. SUSD3D can use the flux moment files produced by the DORT, TORT [7], ONEDANT, TWODANT and THREEDANT [8] discrete ordinates codes. The method used in the SUSD code based on the angular flux files from the ANISN [9] and DOT-III codes was kept for comparison, - Processing codes were updated to the ENDF-6 Format, - Processing of SAD covariance matrices was programmed, - Complete SAD covariance matrices can be taken into account in SUSD3D to calculate the variance. NEA-1628/03: This version differs from the previous one in the following points: Modifications are relevant for the sensitivity calculations of the critical systems and include: - Correction of the sensitivity calculation for prompt fission and number of delayed neutrons per fission (MT=18 and MT=455). - An option allows the re-normalisation of the prompt fission spectra covariance matrices to be applied via the 'normalisation' of the sensitivity profiles. This option is useful in case if the fission spectra covariances (MF=35) used do not comply with the ENDF-6 Format Manual rules. - For the criticality calculations the
Prinsloo, Rian Hendrik
2006-01-01
Nodal diffusion methods have been used extensively in nuclear reactor calculations specifically for their performance advantage, but also their superior accuracy. In this work a nodal diffusion method is developed for three-dimensional cylindrical geometry. Recent developments in the Pebble Bed Modular Reactor (PBMR) project have sparked renewed interest in the application of different modelling methods to its design, and naturally included in this effort is a nodal method for ...
3-dimensional model for Trichel pulses: results of numerical studies for air
It is known that an electric current in a negative corona for pin-to-plane configuration in a wide range of parameters has a form of periodic peaks, which are called Trichel pulses. Recently, authors reported about development of 3-D axially symmetric model intended for numerical simulations of Trichel pulses. In this paper authors present results of numerical simulations of a long train of pulses for pin with hemispherical cap to plane anode configuration in ambient air at atmospheric pressure. These calculations provide information about dynamics of Trichel pulse starting from step-wise voltage applying. Calculations clearly demonstrate that regular current oscillations are established after 4-5 pulses. Space-time evolution of electric field and charged species densities within one cycle of regular oscillations is described in detail. In particular, distributions of specific components of current density over the cathode and anode surfaces were found in dependence on time. Comparison is made with experimentally available data. In contrast to simplified 1.5-D model predicting two-peak shape of Trichel pulse, the exact 3D model predicts single-peaked pulses when ion induced secondary emission processes are included, and photo-emission is neglected. On the anode surface, radial profiles of electric field and ion and electron current components were calculated. Variations of individual current pulse amplitude and shape with discharge voltage growth are studied, too. (author)
Solution of 3-dimensional time-dependent viscous flows. Part 2: Development of the computer code
Weinberg, B. C.; Mcdonald, H.
1980-01-01
There is considerable interest in developing a numerical scheme for solving the time dependent viscous compressible three dimensional flow equations to aid in the design of helicopter rotors. The development of a computer code to solve a three dimensional unsteady approximate form of the Navier-Stokes equations employing a linearized block emplicit technique in conjunction with a QR operator scheme is described. Results of calculations of several Cartesian test cases are presented. The computer code can be applied to more complex flow fields such as these encountered on rotating airfoils.
Depletion capability of the 3-dimensional whole core transport code DeCART
Three dimensional whole-core transport code DeCART has been developed to include the characteristics of a numerical reactor to replace a part of an experiment. This code can be a substitute for the conventional 2-step procedure of the reactor physics analysis. This code adopts the deterministic method for simulating the neutron behavior with the least amount of assumptions and approximations. This neutronic code already included the capability for the transient and thermal hydraulic feedback calculations. A depletion module has been implemented into the DeCART code to predict the depleted composition in a fuel, which adopts the exponential matrix method of ORIGEN-2. Libraries including the decay constants, yield matrix and one-group cross sections have been used and greatly simplified for a calculation efficiency. The computational results for the benchmark problems including the UO2 and MOX fuels show that the depletion module of the whole-core transport code DeCART works reasonably well. (authors)
Liu, Yu
2016-05-11
I developed a novel time-dependent density functional theory (TDDFT) and applied it to complicated 3-dimensional systems for the first time. Superior to conventional TDDFT, the diffusion coefficient is modeled as a function of density profile, which is self-determined by the entropy scaling rule instead using an input parameter. The theory was employed to mimic gas diffusion in a nanoporous material. The TDDFT prediction on the transport diffusivity was reasonable compared to simulations. Moreover, the time-dependent density profiles gave an insight into the microscopic mechanism of the diffusion process. PMID:27121986
Ahn, J S; Kihm, H W; Kihm, J E; Kim, D S; Lee, K G
2009-02-16
We have measured local electric field polarization vectors in 3-dimensional space on the nanoscale. A radial polarized light is generated by using a radial polarization converter and focused by an objective lens. Gold nanoparticle functionalized tips are used to scatter the focused field into the far-field region. Two different methods, rotational analyzer ellipsometry and Stokes parameters, are used in determining the polarization state of the scattered light. Two methods give consistent results with each other. Three dimensional local polarization vectors could be reconstructed by applying back transformation of the fully characterized polarizability tensor of the tip. PMID:19219131
Maschio, Federico; Pandya, Mirali; Olszewski, Raphael
2016-01-01
Background The objective of this study was to investigate the accuracy of 3-dimensional (3D) plastic (ABS) models generated using a low-cost 3D fused deposition modelling printer. Material/Methods Two human dry mandibles were scanned with a cone beam computed tomography (CBCT) Accuitomo device. Preprocessing consisted of 3D reconstruction with Maxilim software and STL file repair with Netfabb software. Then, the data were used to print 2 plastic replicas with a low-cost 3D fused deposition mo...
Xu, Kerui; Liu, Qian; Jackson, Kimberly R.; Landers, James P.
2016-02-01
We developed a microfluidic scanner-based profile exploration system, μSCAPE, capable of generating high resolution 3D profiles of microstructure architecture in a variety of transparent substrates. The profile is obtained by scanning the dye-filled microstructure followed by absorbance calculation and the reconstruction of the optical length at each point. The power of the method was demonstrated in (1) the inspection of the variation of the cross-section of laser-ablated PDMS channel; (2) the volume of PeT chamber; and (3) the population distribution of the volumes of the micro wells in HF-etched glass and laser-ablated PDMS. The reported methods features low equipment-cost, convenient operation and large field of view (FOV), and has revealed unreported quality parameters of the tested microstructures.
OSCAR2000 : a multi-component 3-dimensional oil spill contingency and response model
Researchers at SINTEF in Norway have studied the weathering of surface oil. They developed a realistic model to analyze alternative spill response strategies. The model represented the formation and composition of the water-accommodated fraction (WAF) of oil for both treated and untreated oil spills. As many as 25 components, pseudo-components, or metabolites were allowed for the specification of oil. Calculations effected using OSCAR were verified in great detail on numerous occasions. The model made it possible to determine rather realistically the dissolution, transformation, and toxicology of dispersed oil clouds, as well as evaporation, emulsification, and natural dispersion. OSCAR comprised a data-based oil weathering model, a three-dimensional oil trajectory and chemical fates model, an oil spill combat model, exposure models for birds, marine mammals, fish and ichthyoplankton. 17 refs., 1 tab., 11 figs
The verification of 3 dimensional nodal kinetics code ANCK using transient benchmark problems
Three-dimensional (3D) neutronics and thermal-and-hydraulics (T/H) coupling code, ANCK/MIDAC, has been developed. ANCK/MIDAC consisted of the 3D nodal kinetic code ANCK and the 3D drift flux T/H code MIDAC. In order to verify the adequacy of ANCK that is a kinetics engine of this coupling code, several international benchmark problems have been performed. The calculation results of LMW (Langenbuch, Maurer and Werner) benchmark problems, PWR rod ejection benchmarks and PWR benchmarks on uncontrolled withdrawal of control rods at zero power are shown in this paper. The comparison of the results with the reference solutions shows very good agreements with the main core parameters. (author)
Xu, Kerui; Liu, Qian; Jackson, Kimberly R; Landers, James P
2016-01-01
We developed a microfluidic scanner-based profile exploration system, μSCAPE, capable of generating high resolution 3D profiles of microstructure architecture in a variety of transparent substrates. The profile is obtained by scanning the dye-filled microstructure followed by absorbance calculation and the reconstruction of the optical length at each point. The power of the method was demonstrated in (1) the inspection of the variation of the cross-section of laser-ablated PDMS channel; (2) the volume of PeT chamber; and (3) the population distribution of the volumes of the micro wells in HF-etched glass and laser-ablated PDMS. The reported methods features low equipment-cost, convenient operation and large field of view (FOV), and has revealed unreported quality parameters of the tested microstructures. PMID:26924294
Volpov, Beth L; Rosen, David A S; Trites, Andrew W; Arnould, John P Y
2015-08-01
We tested the ability of overall dynamic body acceleration (ODBA) to predict the rate of oxygen consumption ([Formula: see text]) in freely diving Steller sea lions (Eumetopias jubatus) while resting at the surface and diving. The trained sea lions executed three dive types-single dives, bouts of multiple long dives with 4-6 dives per bout, or bouts of multiple short dives with 10-12 dives per bout-to depths of 40 m, resulting in a range of activity and oxygen consumption levels. Average metabolic rate (AMR) over the dive cycle or dive bout calculated was calculated from [Formula: see text]. We found that ODBA could statistically predict AMR when data from all dive types were combined, but that dive type was a significant model factor. However, there were no significant linear relationships between AMR and ODBA when data for each dive type were analyzed separately. The potential relationships between AMR and ODBA were not improved by including dive duration, food consumed, proportion of dive cycle spent submerged, or number of dives per bout. It is not clear whether the lack of predictive power within dive type was due to low statistical power, or whether it reflected a true absence of a relationship between ODBA and AMR. The average percent error for predicting AMR from ODBA was 7-11 %, and standard error of the estimated AMR was 5-32 %. Overall, the extensive range of dive behaviors and physiological conditions we tested indicated that ODBA was not suitable for estimating AMR in the field due to considerable error and the inconclusive effects of dive type. PMID:26002519
Griffioen, J.; van der Grift, B.; Maas, D.; van den Brink, C.; Zaadnoordijk, J. W.
2003-04-01
Groundwater is contaminated at the regional scale by agricultural activities and atmospheric deposition. A 3-D transport model was set-up for a phreatic drinking water winning, where the groundwater composition was monitored accurately. The winning is situated at an area with unconsolidated Pleistocene deposits. The land use is nature and agriculture. Annual mass-balances were determined using a wide range of historic data. The modelling approach for the unsaturated zone was either simple box models (Cl, NO_3 and SO_4) or 1-D transport modelling using HYDRUS (Cd). The modelling approach for the saturated zone used a multiple solute version of MT3D, where denitrification associated with pyrite oxidation and sorption of Cd were included. The solute transport calculations were performed for the period 1950--2030. The results obtained for the year 2000 were used as input concentration for the period 2000--2030. A comparison between the calculated and the measured concentrations of groundwater abstracted for Cl, NO_3 and SO_4 yields the following. First, the input at the surface is rather well estimated. Second, the redox reactivity of the first two aquifers is negligible around the winning, which is confirmed by respiration experiments using anaerobically sampled aquifer sediments. The reactivity of the third aquifer, which is a marine deposit and lies at least 30 meters below surface, is considerable. The discrepancies between modelled and measured output are explained by lack of knowledge about the subsurface reactivity and/or wrong estimates of surface loading and leaching from the unsaturated zone. The patterns for other hydrogeochemical variables such as Ca, HCO_3 may further constrain this lack of knowledge. The results for Cd indicate that Cd becomes strongly retarded, despite the low reactivity of the sandy sediments. The winning is rather insensitive to Cd contamination (but the surface water drainage network is not). Two major uncertainties for input of Cd
Broad-band near-field ground motion simulations in 3-dimensional scattering media
Imperatori, W.
2012-12-06
The heterogeneous nature of Earth\\'s crust is manifested in the scattering of propagating seismic waves. In recent years, different techniques have been developed to include such phenomenon in broad-band ground-motion calculations, either considering scattering as a semi-stochastic or purely stochastic process. In this study, we simulate broad-band (0–10 Hz) ground motions with a 3-D finite-difference wave propagation solver using several 3-D media characterized by von Karman correlation functions with different correlation lengths and standard deviation values. Our goal is to investigate scattering characteristics and its influence on the seismic wavefield at short and intermediate distances from the source in terms of ground motion parameters. We also examine scattering phenomena, related to the loss of radiation pattern and the directivity breakdown. We first simulate broad-band ground motions for a point-source characterized by a classic ω2 spectrum model. Fault finiteness is then introduced by means of a Haskell-type source model presenting both subshear and super-shear rupture speed. Results indicate that scattering plays an important role in ground motion even at short distances from the source, where source effects are thought to be dominating. In particular, peak ground motion parameters can be affected even at relatively low frequencies, implying that earthquake ground-motion simulations should include scattering also for peak ground velocity (PGV) calculations. At the same time, we find a gradual loss of the source signature in the 2–5 Hz frequency range, together with a distortion of the Mach cones in case of super-shear rupture. For more complex source models and truly heterogeneous Earth, these effects may occur even at lower frequencies. Our simulations suggests that von Karman correlation functions with correlation length between several hundred metres and few kilometres, Hurst exponent around 0.3 and standard deviation in the 5–10 per cent
Shiota, Takahiro; Jones, Michael; Tsujino, Hiroyuki; Qin, Jian Xin; Zetts, Arthur D.; Greenberg, Neil L.; Cardon, Lisa A.; Panza, Julio A.; Thomas, James D.
2002-01-01
BACKGROUND: For evaluating patients with aortic regurgitation (AR), regurgitant volumes, left ventricular (LV) stroke volumes (SV), and absolute LV volumes are valuable indices. AIM: The aim of this study was to validate the combination of real-time 3-dimensional echocardiography (3DE) and semiautomated digital color Doppler cardiac flow measurement (ACM) for quantifying absolute LV volumes, LVSV, and AR volumes using an animal model of chronic AR and to investigate its clinical applicability. METHODS: In 8 sheep, a total of 26 hemodynamic states were obtained pharmacologically 20 weeks after the aortic valve noncoronary (n = 4) or right coronary (n = 4) leaflet was incised to produce AR. Reference standard LVSV and AR volume were determined using the electromagnetic flow method (EM). Simultaneous epicardial real-time 3DE studies were performed to obtain LV end-diastolic volumes (LVEDV), end-systolic volumes (LVESV), and LVSV by subtracting LVESV from LVEDV. Simultaneous ACM was performed to obtain LVSV and transmitral flows; AR volume was calculated by subtracting transmitral flow volume from LVSV. In a total of 19 patients with AR, real-time 3DE and ACM were used to obtain LVSVs and these were compared with each other. RESULTS: A strong relationship was found between LVSV derived from EM and those from the real-time 3DE (r = 0.93, P clinically applicable.
Goldstein, L.; Prasher, S. O.; Ghoshal, S.
2004-05-01
Non-aqueous phase liquids (NAPLs), if spilled into the subsurface, will migrate downward, and a significant fraction will become trapped in the soil matrix. These trapped NAPL globules partition into the water and/or vapor phase, and serve as continuous sources of contamination (e.g. source zones). At present, the presence of NAPL in the subsurface is typically inferred from chemical analysis data. There are no accepted methodologies or protocols available for the direct characterization of NAPLs in the subsurface. Proven and cost-effective methodologies are needed to allow effective implementation of remediation technologies at NAPL contaminated sites. X-ray Computed Tomography (CT) has the potential to non-destructively quantify NAPL mass and distribution in soil cores due to this technology's ability to detect small atomic density differences of solid, liquid, gas, and NAPL phases present in a representative volume element. We have demonstrated that environmentally significant NAPLs, such as gasoline and other oil products, chlorinated solvents, and PCBs possess a characteristic and predictable X-ray attenuation coefficient that permits their quantification in porous media at incident beam energies, typical of medical and industrial X-ray CT scanners. As part of this study, methodologies were developed for generating and analyzing X-ray CT data for the study of NAPLs in natural porous media. Columns of NAPL-contaminated soils were scanned, flushed with solvents and water to remove entrapped NAPL, and re-scanned. X-ray CT data was analyzed to obtain numerical arrays of soil porosity, NAPL saturation, and NAPL volume at a spatial resolution of 1 mm. This methodology was validated using homogeneous and heterogeneous soil columns with known quantities of gasoline and tetrachloroethylene. NAPL volumes computed using X-ray CT data was compared with known volumes from volume balance calculations. Error analysis revealed that in a 5 cm long and 2.5 cm diameter soil
Gosling, J. T.; Birn, J.; McComas, D. J.; Phillips, J. L.; Hesse, M.
1995-01-01
Measurements of suprathermal electron fluxes in the solar wind at energies greater than approximatley 80 eV indicate that magnetic field lines within coronal mass ejections. CMEs, near and beyond 1 AU are normally connected to the Sun at both ends. However, a preliminary reexamination of events previously identified as CMEs in the ISEE 3 data reveals that about 1/4 of all such events contain limited regions where field lines appear to be either connected to the Sun at only one end or connected to the outer heliosphere at both ends. Similar intervals of open and disconnected field lines within CMEs have been identified in the Ulysses observations. We believe that these anomalous field topologies within CMEs are most naturally interpreted in terms of 3-dimensional reconnection behind CMEs close to the Sun. Such reconnection also provides a natural explanation both for the flux rope topology of many CMEs as well as the coronal loops formed during long-duration solar soft X ray events. Although detailed numerical simulations of 3-dimensional reconnection behind CMEs are not yet available, such simulations have been done for the qualitatively similar geometry that prevails within the geomagnetic tail. Those simulations of plasmoid formation in the geomagnetic tail do produce the mixture of field topologies within plasmoids discussed here for CMEs.
This study was to evaluate the influence of slice thickness of computed tomography (CT) and rapid protyping (RP) type on the accuracy of 3-dimensional medical model. Transaxial CT data of human dry skull were taken from multi-detector spiral CT. Slice thickness were 1, 2, 3 and 4 mm respectively. Three-dimensional image model reconstruction using 3-D visualization medical software (V-works 3.0) and RP model fabrication were followed. 2-RP models were 3D printing (Z402, Z Corp., Burlington, USA) and Stereolithographic Apparatus model. Linear measurements of anatomical landmarks on dry skull, 3-D image model, and 2-RP models were done and compared according to slice thickness and RP model type. There were relative error percentage in absolute value of 0.97, 1.98, 3.83 between linear measurements of dry skull and image models of 1, 2, 3 mm slice thickness respectively. There was relative error percentage in absolute value of 0.79 between linear measurements of dry skull and SLA model. There was relative error difference in absolute value of 2.52 between linear measurements of dry skull and 3D printing model. These results indicated that 3-dimensional image model of thin slice thickness and stereolithographic RP model showed relative high accuracy.
Biswas, Debabrata; Kumar, Raghwendra
2015-01-01
Numerical solution of the Poisson equation in metallic enclosures, open at one or more ends, is important in many practical situations such as High Power Microwave (HPM) or photo-cathode devices. It requires imposition of a suitable boundary condition at the open end. In this paper, methods for solving the Poisson equation are investigated for various charge densities and aspect ratios of the open ends. It is found that a mixture of second order and third order local asymptotic boundary condition (ABC) is best suited for large aspect ratios while a proposed non-local matching method, based on the solution of the Laplace equation, scores well when the aspect ratio is near unity for all charge density variations, including ones where the centre of charge is close to an open end or the charge density is non-localized. The two methods complement each other and can be used in electrostatic calculations where the computational domain needs to be terminated at the open boundaries of the metallic enclosure.
An active 3-dimensional localization scheme for femtocell subscribers using E-UTRAN
Mohammed, Aquil Mirza
2012-05-01
Femtocells provide an efficient solution to overcome the indoor coverage problems and also to deal with the traffic within Macro cells. The possibility of localizing femtocell subscriber stations based on the timing ranging advance parameter (TRAP), obtained from E-UTRAN (Evolved UMTS Terrestrial Radio Access Network), within the network signal internals is challenging and is studied throughout in this paper. The principle approach to localization based on Euclidean distances from multiple base stations is outlined.We investigate the specifications of the timing parameters or TRAP used for air interface of 4G network as they relate to calculating the subscriber distances. Computer simulation is used to demonstrate the localization accuracy using multiple base station networks when estimating likely locations of femtocell subscribers stations on a twodimensional coordinate mapping system. However, we further extend our simulations to demonstrate expected location accuracy of subscriber stations, for multiple base station networks, on a three dimensional coordinate mapping scheme. The possibility of of error-fixes shows eight times greater accuracy than in previous results is expected to achieve by applying timing advance techniques to Global System for Mobile communications networks, by using a two-dimensional coordinate mapping scheme. We later compare our study with the effect of global positioning system (GPS) by using a three-dimensional coordinate mapping scheme, which is predicted to give an 72.4 cms accuracy of subscriber station location. © 2012 IEEE.
Development of 3-D detailed FBR core calculation method based on method of characteristics
A new detailed 3-D transport calculation method taking into account the heterogeneity of fuel assemblies has been developed in hexagonal-z geometry by combining the method of characteristics (MOC) and the nodal transport method. From the nodal transport calculation which uses assembly homogenized cross sections, the axial leakage is calculated, and it is used for the MOC calculation which treats the heterogeneity of fuel assemblies. Series of homogeneous MOC calculations which use assembly homogeneous cross sections are carried out to obtain effective cross sections, which preserve assembly reaction rates. This effective cross sections are again used in the 3-dimensional nodal transport calculation. The numerical calculations have been performed to verify 3-dimensional radial calculations of FBR (fast breeder reactor) assemblies and partial core calculations. Results are compared with the reference Monte-Carlo calculations. A good agreement has been achieved. It is shown that the present method has an advantage in calculating reaction rates in a small region. (authors)
The numerical solution of multi-dimensional partial differential equations poses extremely high demands on computing capacity. For the solution of the 3-dimensional partial differential equations of the fluiddynamics a semidiscrete solution technique (discrete in space, continuous in time) is used. The resulting large system of ordinary differential equations (103 - 105 unknowns) may be oscillatory stiff which requires for its efficient solution an ODE-solver of high order which is A (α) - stable, with α > 890. The ODE-solver FEBE is presented which can make use of parallel processing on the subroutine level. Parallelisation is possible on the level of the general ODE-solver algorithm and on the level of solving the implicit matrix equation. For the solution of the implicit matrix equation system a fractional step method is used which is well qualified for parallel computing
Evaluation of 3 dimensional CT angiography (3D-CTA) in internal A-V fistula complications
We examined internal A-V fistula complications in 6 patients using 3D-CTA and plain angiography of internal A-V fistulae (PAG). Technical specifications of 3D-CTA were carried out with a CT scan unit (X vison GX, Toshiba, Japan) using the shade surface display method. As to visualization of various changes occurring in vascular structures. 3D-CTA was comparable to PAG. Furthermore, 3D-CTA allowed superior visualization of arteries and veins in patients with a large shunt blood volume. Although further improvement of software, in terms of 3 dimensional reconstruction, is needed we consider this a potentially valuable tool for examining internal A-V fistula complications. (author)
Eckardt, Henrik; Lind, Dennis; Toendevold, Erik
2015-01-01
Background and purpose - During acetabular fracture surgery, the acetabular roof is difficult to visualize with 2-dimensional fluoroscopic views. We assessed whether intraoperative 3-dimensional (3D) imaging can aid the surgeon to achieve better articular reduction and improve implant fixation....... Patients and methods - We operated on 72 acetabular fractures using intraoperative 3D imaging and compared the operative results, duration of surgery, and complications with those for 42 consecutive acetabular fracture operations conducted using conventional fluoroscopic imaging. Postoperative reduction...... was evaluated on reconstructed coronal and sagittal images of the acetabulum. Results - The fracture severity and patient characteristics were similar in the 2 groups. In the 3D group, 46 of 72 patients (0.6) had a perfect result after open reduction and internal fixation, and in the control group, 17...
Evaluation of 3 dimensional CT angiography (3D-CTA) in internal A-V fistula complications
Yanagisawa, Takayoshi; Otsubo, Osamu; Takahashi, Ikuo [Towa Hospital, Tokyo (Japan)] [and others
1997-02-01
We examined internal A-V fistula complications in 6 patients using 3D-CTA and plain angiography of internal A-V fistulae (PAG). Technical specifications of 3D-CTA were carried out with a CT scan unit (X vison GX, Toshiba, Japan) using the shade surface display method. As to visualization of various changes occurring in vascular structures. 3D-CTA was comparable to PAG. Furthermore, 3D-CTA allowed superior visualization of arteries and veins in patients with a large shunt blood volume. Although further improvement of software, in terms of 3 dimensional reconstruction, is needed we consider this a potentially valuable tool for examining internal A-V fistula complications. (author)
We preoperatively examined 45 patients to investigate the frequency of an anomalous vertebral artery (VA) and the presence of a posterior communicating artery (PCOM) using 3-dimensional CT angiography (3D-CTA). Asymmetry of the VAs was detected in eight patients (18%). Anomalous VAs in the intra- or extraosseous region, including a high-riding VA, persistent 1st intersegmental artery, and ponticulus posticus, were found in a total of 8 patients (18%). Nineteen patients (42%) did not have a PCOM on either side. When a VA, especially the VA on the dominant side, is injured during cervical instrumentation, catastrophic vascular complications occur in approximately 7% of patients who have asymmetrical VAs without collateral circulation. Preoperative 3D-CTA provides information on anomalous VAs and collateral circulation that is crucial to preventing vascular complications. (author)
Sectoring method for cosmic radiation shielding calculation for LEO satellite
One of an approximate calculation model (sectoring method) is developed for a cosmic radiation shielding in satellite. Shielding calculation is performed for KITSAT-1 at the assumed SAA (South Atlatic Anomaly) location with AP-8 model radiation spectrum. When sectoring method is applied, calculation error is expected compared with 3-D detailed geometry calculation because of straight knock-on assumption neglecting the deflection of incident proton. However, sectoring method shows good agreements with 3-dimensional detailed Monte Carlo calculation in two TID detector locations
Purpose: To assess the cost-effectiveness of intensity modulated radiation therapy (IMRT) versus 3-dimensional conformal radiation therapy (3D-CRT) in the treatment of head-and neck-cancer (HNC). Methods and Materials: We used a Markov model to simulate radiation therapy-induced xerostomia and dysphagia in a hypothetical cohort of 65-year-old HNC patients. Model input parameters were derived from PARSPORT (CRUK/03/005) patient-level trial data and quality-of-life and Medicare cost data from published literature. We calculated average incremental cost-effectiveness ratios (ICERs) from the US health care perspective as cost per quality-adjusted life-year (QALY) gained and compared our ICERs with current cost-effectiveness standards whereby treatment comparators less than $50,000 per QALY gained are considered cost-effective. Results: In the first 2 years after initial treatment, IMRT is not cost-effective compared with 3D-CRT, given an average ICER of $101,100 per QALY gained. However, over 15 years (remaining lifetime on the basis of average life expectancy of a 65-year-old), IMRT is more cost-effective at $34,523 per QALY gained. Conclusion: Although HNC patients receiving IMRT will likely experience reduced xerostomia and dysphagia symptoms, the small quality-of-life benefit associated with IMRT is not cost-effective in the short term but may be cost-effective over a patient's lifetime, assuming benefits persist over time and patients are healthy and likely to live for a sustained period. Additional data quantifying the long-term benefits of IMRT, however, are needed
Ortega, Ivan; Sinreich, Roman; Volkamer, Rainer
2014-05-01
We present results of 2 dimensional Multi Axis-DOAS (2D-MAX-DOAS) measurements to infer 3-dimensional measurements of trace gases by characterizing boundary layer vertical profiles and near surface azimuth horizontal distribution of NO2 (14 angles covering 360°). We combine the established optimal estimation inversion with a new parameterization approach; the first method to derive NO2 tropospheric vertical profiles and boundary layer height and the second one to retrieve the azimuth horizontal distribution of near surface NO2 mixing ratios, both at multiple wavelengths (350 nm, 450 nm, and 560 nm). This was conducted for three cloud-free days in the framework of the intensive Multi Axis DOAS Comparison campaign for Aerosols and Trace gases (MAD-CAT) in Mainz, Germany 2013. By retrieving NO2 at multiple wavelengths range-resolved distributions of NO2 are derived using an 'Onion-peeling' approach, i.e., exploiting the fact that the optical path lengths at different wavelengths probe different horizontal air masses. We also measure glyoxal (CHOCHO) and formaldehyde (HCHO) distributions, and present to our knowledge the first 3-dimesional trace-gas distribution measurements of CHOCHO by a ground-based instrument. We expand the 2D-MAX-DOAS capabilities to calculate azimuth ratios of HCHO-to-NO2 (RFN) and CHOCHO-to-NO2 (RGN) to pinpoint volatile organic compound (VOC) oxidation chemistry and CHOCHO-to-HCHO (RGF) ratios as an indicator of biogenic and/or anthropogenic VOC emissions. The results of RFN correlate well with RGN and we identify azimuth variations that indicate gradients in the VOC/NOx chemistry that leads to O3 and secondary aerosol production. While there is a clear diurnal pattern in the RFN and RGN, no such variations are observed in the RGF, which shows rather constant values below 0.04 throughout the day, consistent with previous measurements, and indicative of urban air masses.
Kohler, Racquel E. [Department of Health Policy and Management, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (United States); Sheets, Nathan C. [Department of Radiation Oncology, University of North Carolina Hospitals, Chapel Hill, North Carolina (United States); Wheeler, Stephanie B. [Department of Health Policy and Management, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (United States); Nutting, Chris [Royal Marsden Hospital, London, United Kindom (United Kingdom); Hall, Emma [Clinical Trials and Statistics Unit, Division of Clinical Studies, Institute of Cancer Research, London (United Kingdom); Chera, Bhishamjit S., E-mail: bchera@med.unc.edu [Department of Radiation Oncology, University of North Carolina Hospitals, Chapel Hill, North Carolina (United States)
2013-11-15
Purpose: To assess the cost-effectiveness of intensity modulated radiation therapy (IMRT) versus 3-dimensional conformal radiation therapy (3D-CRT) in the treatment of head-and neck-cancer (HNC). Methods and Materials: We used a Markov model to simulate radiation therapy-induced xerostomia and dysphagia in a hypothetical cohort of 65-year-old HNC patients. Model input parameters were derived from PARSPORT (CRUK/03/005) patient-level trial data and quality-of-life and Medicare cost data from published literature. We calculated average incremental cost-effectiveness ratios (ICERs) from the US health care perspective as cost per quality-adjusted life-year (QALY) gained and compared our ICERs with current cost-effectiveness standards whereby treatment comparators less than $50,000 per QALY gained are considered cost-effective. Results: In the first 2 years after initial treatment, IMRT is not cost-effective compared with 3D-CRT, given an average ICER of $101,100 per QALY gained. However, over 15 years (remaining lifetime on the basis of average life expectancy of a 65-year-old), IMRT is more cost-effective at $34,523 per QALY gained. Conclusion: Although HNC patients receiving IMRT will likely experience reduced xerostomia and dysphagia symptoms, the small quality-of-life benefit associated with IMRT is not cost-effective in the short term but may be cost-effective over a patient's lifetime, assuming benefits persist over time and patients are healthy and likely to live for a sustained period. Additional data quantifying the long-term benefits of IMRT, however, are needed.
SRD 166 MEMS Calculator (Web, free access) This MEMS Calculator determines the following thin film properties from data taken with an optical interferometer or comparable instrument: a) residual strain from fixed-fixed beams, b) strain gradient from cantilevers, c) step heights or thicknesses from step-height test structures, and d) in-plane lengths or deflections. Then, residual stress and stress gradient calculations can be made after an optical vibrometer or comparable instrument is used to obtain Young's modulus from resonating cantilevers or fixed-fixed beams. In addition, wafer bond strength is determined from micro-chevron test structures using a material test machine.
Proton beam lithography a maskless direct-write lithographic technique (well suited for producing 3-Dimensional microstructures in a range of resist and semiconductor materials) is demonstrated as an effective tool in the creation of electrically conductive freestanding micro-structures in an Su 8 + Nano Silver polymer composite. The structures produced show non-ohmic conductivity and fit the percolation theory conduction model of tunneling of separated nanoparticles. Measurements show threshold switching and a change in conductivity of at least 4 orders of magnitude. The predictable range of protons in materials at a given energy is exploited in the creation of high aspect ratio, free standing micro-structures, made from a commercially available SU8 Silver nano-composite (GMC3060 form Gersteltec Inc. a negative tone photo-epoxy with added metallic nano-particles(Silver)) to create films with enhanced electrical properties when exposed and cured. Nano-composite films are directly written on with a finely focused MeV accelerated Proton particle beam. The energy loss of the incident proton beams in the target polymer nano- composite film is concentrated at the end of its range, where damage occurs; changing the chemistry of the nano-composite film via an acid initiated polymerization - creating conduction paths. Changing the energy of the incident beams provide exposed regions with different penetration and damage depth - exploited in the demonstrated cantilever microstructure.
Kevin Krughoff
2013-01-01
Full Text Available Background. Prostate cancer is often understaged following 12-core transrectal ultrasound- (TRUS- guided biopsies. Our goal is to understand where cancers are typically missed by this method. Methods. Transperineal 3-dimensional mapping biopsy (3DMB provides a more accurate depiction of disease status than transrectal ultrasound- (TRUS- guided biopsy. We compared 3DMB findings in men with prior TRUS-guided biopsies to determine grade and location of missed cancer. Results were evaluated for 161 men with low-risk organ confined prostate cancer. Results. The number of cancer-positive biopsy zones per patient with TRUS was 1.38 ± 1.21 compared to 3.33 ± 4.06 with 3DMB, with most newly discovered cancers originating from the middle lobe and apex. Approximately half of all newly discovered cancerous zones resulted from anterior 3DMB sampling. Gleason upgrade was recognized in 56 patients using 3DMB. When both biopsy methods found positive cores in a given zone, Gleason upgrades occurred most frequently in the middle left and right zones. TRUS cancer-positive zones not confirmed by 3DMB were most often the basal zones. Conclusion. Most cancer upgrades and cancers missed from TRUS biopsy originated in the middle left zone of the prostate, specifically in anterior regions. Anterior sampling may lead to more accurate diagnosis and appropriate followup.
Maschio, Federico; Pandya, Mirali; Olszewski, Raphael
2016-01-01
BACKGROUND The objective of this study was to investigate the accuracy of 3-dimensional (3D) plastic (ABS) models generated using a low-cost 3D fused deposition modelling printer. MATERIAL AND METHODS Two human dry mandibles were scanned with a cone beam computed tomography (CBCT) Accuitomo device. Preprocessing consisted of 3D reconstruction with Maxilim software and STL file repair with Netfabb software. Then, the data were used to print 2 plastic replicas with a low-cost 3D fused deposition modeling printer (Up plus 2®). Two independent observers performed the identification of 26 anatomic landmarks on the 4 mandibles (2 dry and 2 replicas) with a 3D measuring arm. Each observer repeated the identifications 20 times. The comparison between the dry and plastic mandibles was based on 13 distances: 8 distances less than 12 mm and 5 distances greater than 12 mm. RESULTS The mean absolute difference (MAD) was 0.37 mm, and the mean dimensional error (MDE) was 3.76%. The MDE decreased to 0.93% for distances greater than 12 mm CONCLUSIONS Plastic models generated using the low-cost 3D printer UPplus2® provide dimensional accuracies comparable to other well-established rapid prototyping technologies. Validated low-cost 3D printers could represent a step toward the better accessibility of rapid prototyping technologies in the medical field. PMID:27003456
Shirakawa, Takashi; Koyama, Yasushi; Mizoguchi, Hiroki; Yoshitatsu, Masao
2016-05-01
We present a case of a double-chambered right ventricle in adulthood, in which we tried a detailed morphological assessment and preoperative simulation using 3-dimensional (3D) heart models for improved surgical planning. Polygonal object data for the heart were constructed from computed tomography images of this patient, and transferred to a desktop 3D printer to print out models in actual size. Medical staff completed all of the work processes. Because the 3D heart models were examined by hand, observed from various viewpoints and measured by callipers with ease, we were able to create an image of the complete form of the heart. The anatomical structure of an anomalous bundle was clearly observed, and surgical approaches to the lesion were simulated accurately. During surgery, we used an incision on the pulmonary infundibulum and resected three muscular components of the stenosis. The similarity between the models and the actual heart was excellent. As a result, the operation for this rare defect was performed safely and successfully. We concluded that the custom-made model was useful for morphological analysis and preoperative simulation. PMID:26860990
Maschio, Federico; Pandya, Mirali; Olszewski, Raphael
2016-01-01
Background The objective of this study was to investigate the accuracy of 3-dimensional (3D) plastic (ABS) models generated using a low-cost 3D fused deposition modelling printer. Material/Methods Two human dry mandibles were scanned with a cone beam computed tomography (CBCT) Accuitomo device. Preprocessing consisted of 3D reconstruction with Maxilim software and STL file repair with Netfabb software. Then, the data were used to print 2 plastic replicas with a low-cost 3D fused deposition modeling printer (Up plus 2®). Two independent observers performed the identification of 26 anatomic landmarks on the 4 mandibles (2 dry and 2 replicas) with a 3D measuring arm. Each observer repeated the identifications 20 times. The comparison between the dry and plastic mandibles was based on 13 distances: 8 distances less than 12 mm and 5 distances greater than 12 mm. Results The mean absolute difference (MAD) was 0.37 mm, and the mean dimensional error (MDE) was 3.76%. The MDE decreased to 0.93% for distances greater than 12 mm. Conclusions Plastic models generated using the low-cost 3D printer UPplus2® provide dimensional accuracies comparable to other well-established rapid prototyping technologies. Validated low-cost 3D printers could represent a step toward the better accessibility of rapid prototyping technologies in the medical field. PMID:27003456
Shwet Prakash
2014-04-01
Full Text Available Ballast water systems in large LNG carriers are essential for proper operations and stability. Water withdrawn from the surrounding environment to supply to the ballast can pose entrainment and impingement risk to the resident fish population. Quantification of these risks and the net effect on population is usually quite challenging and complex. Various methods over the last several decades have been developed and are available in the literature for quantification of entrainment of mobile and immobile lifestages of resident fish. In this study, a detailed 3-dimensional model was developed to estimate the entrainment of ichthyoplankton (fish eggs and larvae and fish from an estuarine environment during the repeated short-term operation of a ballast water intake for an LNG carrier. It was also used to develop a zone of influence to determine the ability of mobile life stages to avoid impingement. The ichthyoplankton model is an Equivalent Adult Model (EAM and assesses the number of breeding adults lost to the population. The EAM incorporates four different methods developed between 1978 and 2005. The study also considers the uncertainty in estimates for the lifestage data and, as such, performs sensitivity analyses to evaluate the confidence level achievable in such quantitative estimates for entrainment.
Tai, Yanlong; Lubineau, Gilles
2016-01-01
Recently, flexible and transparent conductive films (TCFs) are drawing more attention for their central role in future applications of flexible electronics. Here, we report the controllable fabrication of TCFs for moisture-sensing applications based on heating-rate-triggered, 3-dimensional porous conducting networks through drop casting lithography of single-walled carbon nanotube (SWCNT)/poly(3,4-ethylenedioxythiophene)-polystyrene sulfonate (PEDOT:PSS) ink. How ink formula and baking conditions influence the self-assembled microstructure of the TCFs is discussed. The sensor presents high-performance properties, including a reasonable sheet resistance (2.1 kohm/sq), a high visible-range transmittance (>69%, PET = 90%), and good stability when subjected to cyclic loading (>1000 cycles, better than indium tin oxide film) during processing, when formulation parameters are well optimized (weight ratio of SWCNT to PEDOT:PSS: 1:0.5, SWCNT concentration: 0.3 mg/ml, and heating rate: 36 °C/minute). Moreover, the benefits of these kinds of TCFs were verified through a fully transparent, highly sensitive, rapid response, noncontact moisture-sensing device (5 × 5 sensing pixels). PMID:26818091
Tai, Yanlong
2016-01-28
Recently, flexible and transparent conductive films (TCFs) are drawing more attention for their central role in future applications of flexible electronics. Here, we report the controllable fabrication of TCFs for moisture-sensing applications based on heating-rate-triggered, 3-dimensional porous conducting networks through drop casting lithography of single-walled carbon nanotube (SWCNT)/poly(3,4-ethylenedioxythiophene)-polystyrene sulfonate (PEDOT:PSS) ink. How ink formula and baking conditions influence the self-assembled microstructure of the TCFs is discussed. The sensor presents high-performance properties, including a reasonable sheet resistance (2.1 kohm/sq), a high visible-range transmittance (>69%, PET = 90%), and good stability when subjected to cyclic loading (>1000 cycles, better than indium tin oxide film) during processing, when formulation parameters are well optimized (weight ratio of SWCNT to PEDOT:PSS: 1:0.5, SWCNT concentration: 0.3 mg/ml, and heating rate: 36 °C/minute). Moreover, the benefits of these kinds of TCFs were verified through a fully transparent, highly sensitive, rapid response, noncontact moisture-sensing device (5 × 5 sensing pixels).
Löwner, M.-O.
2009-04-01
We present a GML-based application schema for the representation and exchange of true 3-dimensional geomorphologic landforms like rock slopes and their internal and interconnecting processes. Worldwide researchers of very different disciplines work on the behaviour of steep rock slopes and free faces. This behaviour is determined by many factors e.g. the rock slope's geometry, its internal structures, and processes that work on and below the surface. Erosion rates are of interest in terms of both, the geomorphological sediment approach as well as natural risk assessment. The latter refers to buildings and infrastructure in the close vicinity of free faces. While these topics are multi disciplinary research areas an agreement of data description and data exchange is essential to compare results. Geographical data can be shared over the Internet using Web Feature Services. The precondition is the development of a semantic model or ontology based on international standards like GML3 as an implementation of the ISO 109107 and others. Here we propose such an application model for data exchange purposes that fulfils the following requirements: First, an object-oriented view of landforms with a true 3D geometric data format was established. Second, the internal structure and attributes of landforms can be stored. Third, the interaction of processes and landforms is represented. Fourth, the change of all these mentioned attributes over time was considered.
We report on the hydrothermal growth of high quality arrays of single crystalline zinc oxide (ZnO) nanocolumns, oriented perpendicularly to the transparent conductive oxide substrate. In order to obtain precisely defined spacing and arrangement of ZnO nanocolumns over an area up to 0.5 cm2, we used electron beam lithography. Vertically aligned ZnO (multicrystalline or single crystals) nanocolumns were grown in an aqueous solution of zinc nitrate hexahydrate and hexamethylenetetramine at 95 °C, with a growth rate 0.5 ÷ 1 μm/h. The morphology of the nanostructures was visualized by scanning electron microscopy. Such nanostructured ZnO films were used as a substrate for the recently developed 3-dimensional thin film silicon (amorphous, microcrystalline) solar cell, with a high efficiency potential. The photoelectrical and optical properties of the ZnO nanocolumns and the silicon absorber layers of these type nanostructured solar cells were investigated in details. - Highlights: • Vertically-oriented ZnO nanocolumns were grown by hydrothermal method. • The ZnO nanocolumns were grown over an area of 0.5 cm2. • For precise arrangement of the ZnO nanocolumns electron beam lithography was used. • We report on 3-D design of nanostructured solar cell. • Optical thickness of nanostructured cell was three times higher compared to flat cell
Song, Yixuan; Qiang, Tingting; Ye, Ming; Ma, Qiuyang; Fang, Zhen
2015-12-01
Design an effective absorbent that has high surface area, and perfect recyclable is imperative for pollution elimination. Herein, we report a facile two-step strategy to fabricate magnetically separable 3-dimensional (3D) hierarchical carbon-coated nickel (Ni@C) nanocomposites by calcinating nickel based metal organic framework (Ni3(OH)2(C8H4O4)2(H2O)4). SEM and TEM images illuminate that the nanocomposites were constructed by 8 nm nickel nanoparticle encapsulated in 3D flake like carbon. The specific surface area of the obtained nanocomposites is up to 120.38 m2 g-1. Room temperature magnetic measurement indicates the nanocomposites show soft magnetism property, which endows the nanocomposites with an ideal fast magnetic separable property. The maximum adsorption capacity of the nanocomposites for rhodamine B is 84.5 mg g-1. Furthermore, the nanocomposites also exhibit a high adsorption capacity for heavy metal ions. The adsorbent can be very easily separated from the solution by using a common magnet without exterior energy. The as-prepared Ni@C nanocomposites can apply in waste water treatment on a large-scale as a new adsorbent with high efficiency and excellent recyclability.
Tai, Yanlong; Lubineau, Gilles
2016-01-01
Recently, flexible and transparent conductive films (TCFs) are drawing more attention for their central role in future applications of flexible electronics. Here, we report the controllable fabrication of TCFs for moisture-sensing applications based on heating-rate-triggered, 3-dimensional porous conducting networks through drop casting lithography of single-walled carbon nanotube (SWCNT)/poly(3,4-ethylenedioxythiophene)-polystyrene sulfonate (PEDOT:PSS) ink. How ink formula and baking conditions influence the self-assembled microstructure of the TCFs is discussed. The sensor presents high-performance properties, including a reasonable sheet resistance (2.1 kohm/sq), a high visible-range transmittance (>69%, PET = 90%), and good stability when subjected to cyclic loading (>1000 cycles, better than indium tin oxide film) during processing, when formulation parameters are well optimized (weight ratio of SWCNT to PEDOT:PSS: 1:0.5, SWCNT concentration: 0.3 mg/ml, and heating rate: 36 °C/minute). Moreover, the benefits of these kinds of TCFs were verified through a fully transparent, highly sensitive, rapid response, noncontact moisture-sensing device (5 × 5 sensing pixels).
Thrane, Lars; Jørgensen, Thomas Martini; Jørgensen, Mikkel;
2012-01-01
The 3-dimensional imaging of complete polymer solar cells prepared by roll-to-roll coating was carried out using high-resolution 1322 nm optical coherence tomography (OCT) system. We found it possible to image the 3-dimensional structure of the entire solar cell that comprises UV-barrier, barrier...... material, adhesive, substrate and active solar cell multilayer structure. The achievable resolution was 12 μm in the lateral plane and 4.5 μm in the depth. We found that the OCT technique could be readily employed to identify coating defects in the functional layers. We finally identify the limitations of...
Petersen, Kurt Erling
1986-01-01
probabilistic approaches have been introduced in some cases for the calculation of the reliability of structures or components. A new computer program has been developed based upon numerical integration in several variables. In systems reliability Monte Carlo simulation programs are used especially in analysis...... of very complex systems. In order to increase the applicability of the programs variance reduction techniques can be applied to speed up the calculation process. Variance reduction techniques have been studied and procedures for implementation of importance sampling are suggested....
To evaluate the degree of image distortion caused by orthodontic devices during a intracranial magnetic resonance angiography (MRA), and to determine the effectiveness of the 3 dimensional phase-contrast (3D PC). Subjects were divided into group A (n = 20) wearing a home-made orthodontic device, and group B (n = 10) with an actual orthodontic device. A 3.0T MR scanner was used, applying 3D time-of-flight (TOF) and 3D PC. Two board-certified radiologists evaluated images independently based on a four point scale classifying segments of the circle of Willis. Magnetic susceptibility variations and contrast-to-noise ratio (CNR) on maximum intensity projection images were measured. In group A, scores of the 3D TOF and 3D PC were 2.84 ± 0.1 vs. 2.88 ± 0.1 (before) and 1.8 ± 0.4 vs 2.83 ± 0.1 (after wearing device), respectively. In group B, the scores of 3D TOF and 3D PC were 1.86 ± 0.43 and 2.81 ± 0.15 (p = 0.005), respectively. Magnetic susceptibility variations showed meaningful results after wearing the device (p = 0.0001). CNRs of the 3D PC before and after wearing device were 142.9 ± 6.6 vs. 140.8 ± 7.2 (p = 0.7507), respectively. In the 3D TOF, CNRs were 324.8 ± 25.4 vs. 466.3 ± 41.7 (p = 0.0001). The 3D PC may be a solution method for distorted images by magnetic susceptibility in the intracranial MRA compared with 3D TOF.
Skjøth, F; Thorup, Vivi Mørkøre; do Nascimento, Omar Feix; Ingvartsen, Klaus Lønne; Rasmussen, Morten Dam; Voigt, Michael
2013-01-01
force information. Features were derived from measurements made using two parallel 3-dimensional force plates. The approach presented is based on clustering of Centre of Pressure (COP) trace points over space and time, combined with logical sequencing of stance phases based on the dynamics of...
Hatakeyama, Masahiko; Toyama, Takeshi; Nagai, Yasuyoshi;
2008-01-01
Nanostructural evolution of Cr (Cr-rich) precipitates in a Cu-0.78%Cr-0.13%Zr alloy has been studied after aging and overaging (reaging) by laser assisted local electrode 3 dimensional atom probe (Laser-LEAP). This material is a candidate for the first wall and divertor components of future fusion...
Nazarian, N.; Kleissl, J. P.
2014-12-01
As urbanization progresses, microclimate modifications are also aggravated and the increasing environmental concerns call for more sophisticated methods of urban microclimate analysis. Comprehensive numerical simulations for a clear summer day in southern California are performed in a compact low-rise urban environment. The effect of realistic unsteady, non-uniform thermal forcing, that is caused by solar insolation and inter-building shadowing on thermal and flow conditions are analyzed based on Algebraic Wall-Modeled Large Eddy Simulation (LES) model. The urban thermal field is influenced by urban density, material properties and local weather conditions, as well as urban canyon flow. Urban canyon conditions are translated into vertical and horizontal bulk Richardson numbers indicating atmospheric instability and solar tilt with respect to the momentum forcing of the canyon vortex, respectively. The effect of roof heating is found to be critical on the vortex formation between buildings when the vertical bulk Richardson number is low. Variations of Convective Heat Transfer Coefficients (CHTCs) along building walls are studied and the street canyon ventilation performance is characterized by the mean of air exchange rate (ACH). It is found that volumetric air exchange from street canyons, as well as the distribution of heat transfer along the wall depends strongly on the three-dimensional orientation of the heated wall in relation to wind direction. For example, air removal increases by surface heating and is larger when the leeward wall is heated. In summary, we demonstrate the importance of considering complex realistic conditions on 3-dimensional thermal and momentum fields in Urban Environments.
Nakaguchi, Yuji; Ono, Takeshi; Onitsuka, Ryota; Maruyama, Masato; Shimohigashi, Yoshinobu; Kai, Yudai
2016-01-01
COMPASS system (IBA Dosimetry, Schwarzenbruck, Germany) and ArcCHECK with 3DVH software (Sun Nuclear Corp., Melbourne, FL) are commercial quasi-3-dimensional (3D) dosimetry arrays. Cross-validation to compare them under the same conditions, such as a treatment plan, allows for clear evaluation of such measurement devices. In this study, we evaluated the accuracy of reconstructed dose distributions from the COMPASS system and ArcCHECK with 3DVH software using Monte Carlo simulation (MC) for multi-leaf collimator (MLC) test patterns and clinical VMAT plans. In a phantom study, ArcCHECK 3DVH showed clear differences from COMPASS, measurement and MC due to the detector resolution and the dose reconstruction method. Especially, ArcCHECK 3DVH showed 7% difference from MC for the heterogeneous phantom. ArcCHECK 3DVH only corrects the 3D dose distribution of treatment planning system (TPS) using ArcCHECK measurement, and therefore the accuracy of ArcCHECK 3DVH depends on TPS. In contrast, COMPASS showed good agreement with MC for all cases. However, the COMPASS system requires many complicated installation procedures such as beam modeling, and appropriate commissioning is needed. In terms of clinical cases, there were no large differences for each QA device. The accuracy of the compass and ArcCHECK 3DVH systems for phantoms and clinical cases was compared. Both systems have advantages and disadvantages for clinical use, and consideration of the operating environment is important. The QA system selection is depending on the purpose and workflow in each hospital. PMID:27179708
Hypofractionated radiotherapy may overcome repopulation in rapidly proliferating tumors such as lung cancer. It is more convenient for the patients and reduces health care costs. This study reports our results on patients with medically inoperable, early stage, non-small cell lung cancer (NSCLC) treated with hypofractionation. Stage T1-2N0 NSCLC patients were treated with hypofractionation alone, 52.5 Gy/15 fractions, in 3 weeks, with 3-dimensional conformal planning. T1-2N1 patients with the hilar lymphnode close to the primary tumor were also eligible for this treatment. We did not use any approach to reduce respiratory motion, but it was monitored in all patients. Elective nodal radiotherapy was not performed. Routine follow up included assessment for acute and late toxicity and radiological tumor response. Median follow up time was 29 months for the surviving patients. Thirty-two patients with a median age of 76 years, T1 = 15 and T2 = 17, were treated. Median planning target volume (PTV) volume was 150cc and median V16 of both lungs was 13%. The most important finding of this study is that toxicity was minimal. Two patients had grade ≤ 2 acute pneumonitis and 3 had mild (grade 1) acute esophagitis. There was no late toxicity. Actuarial 1 and 2-year overall survival rates are 78% and 56%, cancer specific survival rates (CSS) are 90% and 74%, and local relapse free survival rates are 93% and 76% respectively. 3-D planning, involved field hypofractionation at a dose of 52.5 Gy in 15 daily fractions is safe, well tolerated and easy radiation treatment for medically inoperable lung cancer patients. It shortens by half the traditional treatment. Results compare favorably with previously published studies. Further studies are needed to compare similar technique with other treatments such as surgery and stereotactic radiotherapy
With a type of capacitatively coupled plasma enhanced chemical vapor deposition (PECVD) technique, where two specially designed electrodes face to each other, the inner surface of hollow 3-dimensional objects such as poly(ethylene terephthalate) (PET) bottles can be coated with diamond-like carbon (DLC) thin film. DLC-coated PET bottles obtained with this technique have an enhanced gas barrier property, and therefore are applicable to industrial use such as for the extension of the shelf-life of contents sensitive to gas permeation. In this paper, the impact of power frequency ranging from 2.5 to 13.56 MHz was studied in order to research the behavior of plasma inside PET bottles and resultant properties. Different power frequency turned out to be influential on gas barrier property, the overall and distribution of tint, and adhesion between DLC and PET substrate. In addition, positron annihilation turned out to be powerful tool for the comparison of different coating conditions because it clarifies the homogeneity of DLC thin films through providing information on overall structure and thickness of them. These findings can be used for the optimization not only in the beverage PET bottle application, but also in other capacitatively coupled PECVD devices. - Highlights: • We demonstrated an effective methodology for the homogeneity of thin films. • We described the influence of power frequency on plasma and resultant thin film. • Diamond-like carbon coated on poly(ethylene terephthalate) bottles was used. • Different frequency provided homogenous thin films based on the above methodology. • For the industrial performance of the bottles, optimization was found at 6 MHz
Nakaya, Masaki, E-mail: m-nakaya@kirin.co.jp [Packaging Technology Development Center, Technology Development Department, Kirin Brewery Co., Ltd., 1-17-1 Namamugi, Tsurumi-ku, Yokohama, Kanagawa 230-8682 (Japan); Shimizu, Mari [Packaging Technology Development Center, Technology Development Department, Kirin Brewery Co., Ltd., 1-17-1 Namamugi, Tsurumi-ku, Yokohama, Kanagawa 230-8682 (Japan); Uedono, Akira [Division of Applied Physics, Faculty of Pure and Applied Science, University of Tsukuba, Tsukuba, Ibaraki 305-8573 (Japan)
2014-08-01
With a type of capacitatively coupled plasma enhanced chemical vapor deposition (PECVD) technique, where two specially designed electrodes face to each other, the inner surface of hollow 3-dimensional objects such as poly(ethylene terephthalate) (PET) bottles can be coated with diamond-like carbon (DLC) thin film. DLC-coated PET bottles obtained with this technique have an enhanced gas barrier property, and therefore are applicable to industrial use such as for the extension of the shelf-life of contents sensitive to gas permeation. In this paper, the impact of power frequency ranging from 2.5 to 13.56 MHz was studied in order to research the behavior of plasma inside PET bottles and resultant properties. Different power frequency turned out to be influential on gas barrier property, the overall and distribution of tint, and adhesion between DLC and PET substrate. In addition, positron annihilation turned out to be powerful tool for the comparison of different coating conditions because it clarifies the homogeneity of DLC thin films through providing information on overall structure and thickness of them. These findings can be used for the optimization not only in the beverage PET bottle application, but also in other capacitatively coupled PECVD devices. - Highlights: • We demonstrated an effective methodology for the homogeneity of thin films. • We described the influence of power frequency on plasma and resultant thin film. • Diamond-like carbon coated on poly(ethylene terephthalate) bottles was used. • Different frequency provided homogenous thin films based on the above methodology. • For the industrial performance of the bottles, optimization was found at 6 MHz.
Miyamoto, K.; Hoshino, T.; Hitotsubashi, R.; Yamashita, M.; Ueda, J.
In STS-95 space experiments, etiolated pea seedlings grown under microgravity conditions in space have shown to be automorphosis. Epicotyls were almost straight but the most oriented toward the direction far from their cotyledons with ca. 45 degrees from the vertical line as compared with that on earth. In order to know the mechanism of microgravity conditions in space to induce automorphosis, we introduced simulated microgravity conditions on a 3-dimensional clinostat, resulting in the successful induction of automorphosis-like growth and development. Kinetic studies revealed that epicotyls bent at their basal region or near cotyledonary node toward the direction far from the cotyledons with about 45 degrees in both seedlings grown on 1 g and under simulated microgravity conditions on the clinostat within 48 hrs after watering. Thereafter epicotyls grew keeping this orientation under simulated microgravity conditions on the clinostat, whereas those grown on 1 g changed the growth direction to vertical direction by negative gravitropic response. Automorphosis-like growth and development was induced by the application of auxin polar transport inhibitors (2,3,5-triiodobenzoic acid, N-(1-naphtyl)phthalamic acid, 9-hydroxyfluorene-9-carboxylic acid), but not an anti-auxin, p-chlorophenoxyisobutyric acid. Automorphosis-like epicotyl bending was also phenocopied by the application of inhibitors of stretch-activated channel, LaCl3 and GdCl3, and by the application of an inhibitor of protein kinase, cantharidin. These results suggest that automorphosis-like growth in epicotyls of etiolated pea seedlings is due to suppression of negative gravitropic responses on 1 g, and the growth and development of etiolated pea seedlings under 1 g conditions requires for normal activities of auxin polar transport and the gravisensing system relating to calcium channels. Possible mechanisms of perception and transduction of gravity signals to induce automorphosis are discussed.
NONE
1996-05-01
The Department of Energy (DOE), in conjunction with the Bureau of Land Management (BLM), has prepared an Environmental Assessment (DOE/EA-1124) to identify and evaluate the potential environmental impacts of the proposed geophysical seismic survey on and adjacent to the Naval Petroleum Reserve No.1 (NPR-1), located approximately 35 miles west of Bakersfield, California. NPR-1 is jointly owned and operated by the federal government and Chevron U.S.A. Production Company. The federal government owns about 78 percent of NPR-1, while Chevron owns the remaining 22 percent. The government`s interest is under the jurisdiction of DOE, which has contracted with Bechtel Petroleum Operations, Inc. (BPOI) for the operation and management of the reserve. The 3-dimensional seismic survey would take place on NPR-1 lands and on public and private lands adjacent to NPR-1. This project would involve lands owned by BLM, California Department of Fish and Game (CDFG), California Energy Commission (CEC), The Nature Conservancy, the Center for Natural Lands Management, oil companies (Chevron, Texaco, and Mobil), and several private individuals. The proposed action is designed to provide seismic data for the analysis of the subsurface geology extant in western NPR-1 with the goal of better defining the commercial limits of a currently producing reservoir (Northwest Stevens) and three prospective hydrocarbon bearing zones: the {open_quotes}A Fan{close_quotes} in Section 7R, the 19R Structure in Section 19R, and the 13Z Structure in Section 13Z. Interpreting the data is expected to provide NPR-1 owners with more accurate locations of structural highs, faults, and pinchouts to maximize the recovery of the available hydrocarbon resources in western NPR-1. Completion of this project is expected to increase NPR-1 recoverable reserves, and reduce the risks and costs associated with further exploration and development in the area.
Graphical abstract: - Highlights: • The structural and optical characterizations of ZnO nanoflowers were carried out on ITO by hydrothermal method. • Dye sensitized solar cell based ZnO nanoflowers were constructed on substrate. • The surface morphology effect on quantum efficiency and solar conversion efficiency were investigated. - Abstract: 3-dimensional ZnO nanoflower were obtained on FTO (F:SnO2) substrate by hydrothermal method in order to produce high efficiency dye sensitized solar cells (DSSCs). We showed that nanoflowers structures have nanoscale branches that stretch to fill gaps on the substrate and these branches of nano-leaves provide both a larger surface area and a direct pathway for electron transport along the channels. It was found that the solar conversion efficiency and quantum efficiency (QE) or incident photon to current conversion efficiencies (IPCE) is highly dependent on nanoflower surface due to high electron injection process. The highest solar conversion efficiency of 5.119 and QE of 60% was obtained using ZnO nanoflowers/N719 dye/I−/I−3 electrolyte. In this study, three dimensional (3D)-nanoflower and one dimensional (1D)-nanowires ZnO nanostructures were also compared against each other in respect to solar conversion efficiency and QE measurements. In the case of the 1D-ZnO nanowire conversion efficiency (η) of 2.222% and IPCE 47% were obtained under an illumination of 100 mW/cm2. It was confirmed that the performance of the 3D-nanoflowers was better than about 50% that of the 1D-nanowire dye-sensitized solar cells
Beguería, Santiago; Vicente Serrano, Sergio M.
2009-01-01
[EN] *Objectives: The program calculates time series of the Standardised Precipitation-Evapotransporation Index (SPEI). *Technical Characteristics: The program is executed from the Windows console. From an input data file containing monthly time series of precipitation and mean temperature, plus the geographic coordinates of the observatory, the program computes the SPEI accumulated at the time interval specified by the user, and generates a new data file with the SPEI time serie...
Reviewed is the effect of heat flux of different system parameters on critical density in order to give an initial view on the value of several parameters. A thorough analysis of different equations is carried out to calculate burnout is steam-water flows in uniformly heated tubes, annular, and rectangular channels and rod bundles. Effect of heat flux density distribution and flux twisting on burnout and storage determination according to burnout are commended
Moignier, Alexandra, E-mail: alexandra.moignier@gmail.com [Institut de Radioprotection et de Sûreté Nucléaire, PRP-HOM/SDI/LEDI, Laboratoire d' Evaluation de la Dose Interne, Fontenay-aux-Roses (France); Broggio, David [Institut de Radioprotection et de Sûreté Nucléaire, PRP-HOM/SDI/LEDI, Laboratoire d' Evaluation de la Dose Interne, Fontenay-aux-Roses (France); Derreumaux, Sylvie [Institut de Radioprotection et de Sûreté Nucléaire, PRP-HOM/SER/UEM, Unité d' Expertise en radioprotection Médicale, Fontenay-aux-Roses (France); El Baf, Fida [Institut de Radioprotection et de Sûreté Nucléaire, PRP-HOM/SDI/LEDI, Laboratoire d' Evaluation de la Dose Interne, Fontenay-aux-Roses (France); Mandin, Anne-Marie [Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique - Hôpitaux de Paris, Service de Radiothérapie Oncologique, Paris (France); Girinsky, Théodore [Institut Gustave Roussy, Service de Radiothérapie Oncologique, Villejuif (France); Paul, Jean-François [Centre Chirurgical Marie-Lannelongue, Service de Radiologie, Le Plessis-Robinson (France); and others
2014-05-01
Purpose: In left-side breast radiation therapy (RT), doses to the left main (LM) and left anterior descending (LAD) coronary arteries are usually assessed after delineation by prior anatomic knowledge on the treatment planning computed tomography (CT) scan. In this study, dose sensitivity due to interindividual coronary topology variation was assessed, and hot spots were located. Methods and Materials: Twenty-two detailed heart models, created from heart computed tomography angiographies, were fitted into a single representative female thorax. Two breast RT protocols were then simulated into a treatment planning system: the first protocol comprised tangential and tumoral bed beams (TGs{sub T}B) at 50 + 16 Gy, the second protocol added internal mammary chain beams at 50 Gy to TGs{sub T}B (TGs{sub T}B{sub I}MC). For the heart, the LAD, and the LM, several dose indicators were calculated: dose-volume histograms, mean dose (D{sub mean}), minimal dose received by the most irradiated 2% of the volume (D{sub 2%}), and 3-dimensional (3D) dose maps. Variations of these indicators with anatomies were studied. Results: For the LM, the intermodel dispersion of D{sub mean} and D{sub 2%} was 10% and 11%, respectively, with TGs{sub T}B and 40% and 80%, respectively, with TGs{sub T}B{sub I}MC. For the LAD, these dispersions were 19% (D{sub mean}) and 49% (D{sub 2%}) with TGs{sub T}B and 35% (D{sub mean}) and 76% (D{sub 2%}) with TGs{sub T}B{sub I}MC. The 3D dose maps revealed that the internal mammary chain beams induced hot spots between 20 and 30 Gy on the LM and the proximal LAD for some coronary topologies. Without IMC beams, hot spots between 5 and 26 Gy are located on the middle and distal LAD. Conclusions: Coronary dose distributions with hot spot location and dose level can change significantly depending on coronary topology, as highlighted by 3D coronary dose maps. In clinical practice, coronary imaging may be required for a relevant coronary dose assessment
Purpose: In left-side breast radiation therapy (RT), doses to the left main (LM) and left anterior descending (LAD) coronary arteries are usually assessed after delineation by prior anatomic knowledge on the treatment planning computed tomography (CT) scan. In this study, dose sensitivity due to interindividual coronary topology variation was assessed, and hot spots were located. Methods and Materials: Twenty-two detailed heart models, created from heart computed tomography angiographies, were fitted into a single representative female thorax. Two breast RT protocols were then simulated into a treatment planning system: the first protocol comprised tangential and tumoral bed beams (TGsTB) at 50 + 16 Gy, the second protocol added internal mammary chain beams at 50 Gy to TGsTB (TGsTBIMC). For the heart, the LAD, and the LM, several dose indicators were calculated: dose-volume histograms, mean dose (Dmean), minimal dose received by the most irradiated 2% of the volume (D2%), and 3-dimensional (3D) dose maps. Variations of these indicators with anatomies were studied. Results: For the LM, the intermodel dispersion of Dmean and D2% was 10% and 11%, respectively, with TGsTB and 40% and 80%, respectively, with TGsTBIMC. For the LAD, these dispersions were 19% (Dmean) and 49% (D2%) with TGsTB and 35% (Dmean) and 76% (D2%) with TGsTBIMC. The 3D dose maps revealed that the internal mammary chain beams induced hot spots between 20 and 30 Gy on the LM and the proximal LAD for some coronary topologies. Without IMC beams, hot spots between 5 and 26 Gy are located on the middle and distal LAD. Conclusions: Coronary dose distributions with hot spot location and dose level can change significantly depending on coronary topology, as highlighted by 3D coronary dose maps. In clinical practice, coronary imaging may be required for a relevant coronary dose assessment, especially in cases of internal mammary chain irradiation
McCarty, George
1982-01-01
How THIS BOOK DIFFERS This book is about the calculus. What distinguishes it, however, from other books is that it uses the pocket calculator to illustrate the theory. A computation that requires hours of labor when done by hand with tables is quite inappropriate as an example or exercise in a beginning calculus course. But that same computation can become a delicate illustration of the theory when the student does it in seconds on his calculator. t Furthermore, the student's own personal involvement and easy accomplishment give hi~ reassurance and en couragement. The machine is like a microscope, and its magnification is a hundred millionfold. We shall be interested in limits, and no stage of numerical approximation proves anything about the limit. However, the derivative of fex) = 67.SgX, for instance, acquires real meaning when a student first appreciates its values as numbers, as limits of 10 100 1000 t A quick example is 1.1 , 1.01 , 1.001 , •••• Another example is t = 0.1, 0.01, in the functio...
Risk and reliability analysis is increasingly being used in evaluations of plant safety and plant reliability. The analysis can be performed either during the design process or during the operation time, with the purpose to improve the safety or the reliability. Due to plant complexity and safety and availability requirements, sophisticated tools, which are flexible and efficient, are needed. Such tools have been developed in the last 20 years and they have to be continuously refined to meet the growing requirements. Two different areas of application were analysed. In structural reliability probabilistic approaches have been introduced in some cases for the calculation of the reliability of structures or components. A new computer program has been developed based upon numerical integration in several variables. In systems reliability Monte Carlo simulation programs are used especially in analysis of very complex systems. In order to increase the applicability of the programs variance reduction techniques can be applied to speed up the calculation process. Variance reduction techniques have been studied and procedures for implementation of importance sampling are suggested. (author)
Purpose: To introduce and evaluate a novel deformable 3-dimensional (3D) dosimetry system (Presage-Def/Optical-CT) and its application toward investigating the accuracy of dose deformation in a commercial deformable image registration (DIR) package. Methods and Materials: Presage-Def is a new dosimetry material consisting of an elastic polyurethane matrix doped with radiochromic leuco dye. Radiologic and mechanical properties were characterized using standard techniques. Dose-tracking feasibility was evaluated by comparing dose distributions between dosimeters irradiated with and without 27% lateral compression. A checkerboard plan of 5-mm square fields enabled precise measurement of true deformation using 3D dosimetry. Predicted deformation was determined from a commercial DIR algorithm. Results: Presage-Def exhibited a linear dose response with sensitivity of 0.0032 ΔOD/(Gy∙cm). Mass density is 1.02 g/cm3, and effective atomic number is within 1.5% of water over a broad (0.03-10 MeV) energy range, indicating good water-equivalence. Elastic characteristics were close to that of liver tissue, with Young's modulus of 13.5-887 kPa over a stress range of 0.233-303 kPa, and Poisson's ratio of 0.475 (SE, 0.036). The Presage-Def/Optical-CT system successfully imaged the nondeformed and deformed dose distributions, with isotropic resolution of 1 mm. Comparison with the predicted deformed 3D dose distribution identified inaccuracies in the commercial DIR algorithm. Although external contours were accurately deformed (submillimeter accuracy), volumetric dose deformation was poor. Checkerboard field positioning and dimension errors of up to 9 and 14 mm, respectively, were identified, and the 3D DIR-deformed dose γ passing rate was only γ3%/3mm = 60.0%. Conclusions: The Presage-Def/Optical-CT system shows strong potential for comprehensive investigation of DIR algorithm accuracy. Substantial errors in a commercial DIR were found in the conditions evaluated. This work
A 3-Dimensional Model of Water-Bearing Sequences in the Dominguez Gap Region, Long Beach, California
Ponti, Daniel J.; Ehman, Kenneth D.; Edwards, Brian D.; Tinsley, John C., III; Hildenbrand, Thomas; Hillhouse, John W.; Hanson, Randall T.; McDougall, Kristen; Powell, Charles L.; Wan, Elmira; Land, Michael; Mahan, Shannon; Sarna-Wojcicki, Andrei M.
2007-01-01
A 3-dimensional computer model of the Quaternary sequence stratigraphy in the Dominguez gap region of Long Beach, California has been developed to provide a robust chronostratigraphic framework for hydrologic and tectonic studies. The model consists of 13 layers within a 16.5 by 16.1 km (10.25 by 10 mile) square area and extends downward to an altitude of -900 meters (-2952.76 feet). Ten sequences of late Pliocene to Holocene age are identified and correlated within the model. Primary data to build the model comes from five reference core holes, extensive high-resolution seismic data obtained in San Pedro Bay, and logs from several hundred water and oil wells drilled in the region. The model is best constrained in the vicinity of the Dominguez gap seawater intrusion barrier where a dense network of subsurface data exist. The resultant stratigraphic framework and geologic structure differs significantly from what has been proposed in earlier studies. An important new discovery from this approach is the recognition of ongoing tectonic deformation throughout nearly all of Quaternary time that has impacted the geometry and character of the sequences. Anticlinal folding along a NW-SE trend, probably associated with Quaternary reactivation of the Wilmington anticline, has uplifted and thinned deposits along the fold crest, which intersects the Dominguez gap seawater barrier near Pacific Coast Highway. A W-NW trending fault system that approximately parallels the fold crest has also been identified. This fault progressively displaces all but the youngest sequences down to the north and serves as the southern termination of the classic Silverado aquifer. Uplift and erosion of fining-upward paralic sequences along the crest of the young fold has removed or thinned many of the fine-grained beds that serve to protect the underlying Silverado aquifer from seawater contaminated shallow groundwater. As a result of this process, the potential exists for vertical migration of
Hong Zhou
Full Text Available Various toxicants, drugs and their metabolites carry potential ovarian toxicity. Ovarian follicles, the functional unit of the ovary, are susceptible to this type of damage at all stages of their development. However, despite of the large scale of potential negative impacts, assays that study ovarian toxicity are limited. Exposure of cultured ovarian follicles to toxicants of interest served as an important tool for evaluation of toxic effects for decades. Mouse follicles cultured on the bottom of a culture dish continue to serve an important approach for mechanistic studies. In this paper, we demonstrated the usefulness of a hydrogel based 3-dimensional (3D mouse ovarian follicle culture as a tool to study ovarian toxicity in a different setup. The 3D in vitro culture, based on fibrin alginate interpenetrating network (FA-IPN, preserves the architecture of the ovarian follicle and physiological structure-function relationship. We applied the novel 3D high-throughput (HTP in vitro ovarian follicle culture system to study the ovotoxic effects of an anti-cancer drug, Doxorobucin (DXR. The fibrin component in the system is degraded by plasmin and appears as a clear circle around the encapsulated follicle. The degradation area of the follicle is strongly correlated with follicle survival and growth. To analyze fibrin degradation in a high throughput manner, we created a custom MATLAB® code that converts brightfield micrographs of follicles encapsulated in FA-IPN to binary images, followed by image analysis. We did not observe any significant difference between manually processed images to the automated MATLAB® method, thereby confirming that the automated program is suitable to measure fibrin degradation to evaluate follicle health. The cultured follicles were treated with DXR at concentrations ranging from 0.005 nM to 200 nM, corresponding to the therapeutic plasma levels of DXR in patients. Follicles treated with DXR demonstrated decreased
We study the 3-dimensional pure U(1) lattice gauge theory with Villain action which is related to the 3-dimensional Z-ferro-magnet by an exact duality transformation (and also to a Coulomb system). We show that its string tension α is nonzero for all values of the coupling constant g2, and obeys and bound α >= const x msub(D)β-1 for small ag2, with β = 4π2/g2 and m2sub(D) = (2β/a3)esup(-βupsiloncb(0)/2) (a = lattice spacing). A continuum limit a → 0, msub(D) fixed, exists and represents a scalar free field theory of mass msub(D). The string tension αmsub(D)-2 in physical units tends to infinite in this limit. Characteristic differences in the behavior of the model for large and small coupling constant ag2 are found. Renormalization group aspects are discussed. (orig.)
Thrane, Lars; Jørgensen, Thomas Martini; Jørgensen, Mikkel;
2013-01-01
We have recently demonstrated the first application of optical coherence tomography (OCT) as a 3-dimensional (3D) imaging technique to visualize the internal structure of complete multilayered polymer solar cell modules (Thrane et al., Solar Energy Materials & Solar Cells 97, 181-185 (2012)). The 3......D imaging of complete polymer solar cells prepared by roll-to-roll coating was carried out using a high-resolution 1322nm OCT system having a 4.5 microns axial resolution and a 12 microns lateral resolution. It was possible to image the 3-dimensional structure of the entire solar cell that comprise...... UV-barrier, barrier material, adhesive, substrate and active solar cell multilayer structure. In addition, it was found that the OCT technique could be readily employed to identify coating defects in the functional layers, making it a potential technique to enable process control by real...
2015-01-01
This thesis is based upon the implementation of pocket-size cardiac ultrasound (PCU) among medical students and residents in internal medicine and 3 dimensional echocardiography (3DE) in routine care at a general hospital. The introduction of widely available and handy ultrasound devices has represented a challenge to the medical community as implementation in clinical practice can be made by non-specialists. In view of favorable results from the non-expert use of the larger laptop-sized d...
Dunda, Sebastian E.; Schriever, T.; Rosen, C; C. Opländer; Tolba, R.H.; Diamantouros, S.; Jockenhoevel, S.; Pallua, N
2012-01-01
The creation of musculoskeletal tissue represents an alternative for the replacement of soft tissue in reconstructive surgery. However, most of the approaches of creating artificial tissue have their limitations in the size as the maximally obtainable dimension of bioartificial tissue (BAT) is limited due to the lack of supporting vessels within the 3-dimensional construct. The seeded myoblasts require high amounts of perfusion, oxygen, and nutrients to survive. To achieve this, we developed ...
Lambros, Maria P.; DeSalvo, Michael K.; Jonathan Moreno; Hari Chandana Mulamalla; Lavanya Kondapalli
2015-01-01
Cancer patients who receive radiation are often afflicted by oral mucositis, a debilitating disease, characterized by mouth sores and difficulty in swallowing. Oftentimes, cancer patients afflicted with mucositis must stop life-saving therapies. Thus it is very important to prevent mucositis before it develops. Using a validated organotypic model of human oral mucosa, a 3-dimensional cell culture model of human oral keratinocytes, it has been shown that a mixture (NAC–QYD) of N-acetyl cystein...
Marcus, Hani J; Hughes-Hallett, Archie; Cundy, Thomas P.; Di Marco, Aimee; Pratt, Philip; Nandi, Dipankar; Darzi, Ara; Yang, Guang-Zhong
2013-01-01
BACKGROUND: Although the potential benefits of 3-dimensional (3-D) vs 2-dimensional (2-D) and high-definition (HD) vs standard-definition (SD) endoscopic visualization have long been recognized in other surgical fields, such endoscopes are generally considered too large and bulky for use within the brain. The recent development of 3-D and HD neuroendoscopes may therefore herald improved depth perception, better appreciation of anatomic details, and improved overall surgical performance. OBJEC...
Boyle, A. P.; Williams, M.; Williams, P.
2011-12-01
Spatial ability forms its own category separate from verbal ability. Various spatial abilities have been identified over the last three decades and classified into three types: mental rotation, spatial rotation and spatial visualization, which have been linked to high performance in STEM subjects. Geoscience demands spatial thinking from learners and practitioners, and spatial literacy has been seen as a fundamental skill in Geography, Earth & Environmental Sciences (GEES disciplines) essential for progression. First year GEES students not only have to cope with new learning and teaching environments (Maguire et al., 2008), but, arriving with different science backgrounds, are faced with the challenge of developing essential skills that may be novel for them. These essential skills are subject-specific, as well as transferable, and require an understanding of 3-dimensional spatial relationships. However, spatial skills can be troublesome for some students to master. Not only do many students find difficulty in acquiring spatial skills, facing a succession of hurdles that need to be overcome in developing their understanding, but also educators, often strong spatial thinkers themselves and unaware of the degree to which some students are spatially-challenged, may find it difficult to help. Recent studies have suggested that performance on abstract and applied spatial tasks may be enhanced through instruction and practice and spatially-intensive geoscience courses may strengthen performance on spatial tasks. At Liverpool, many first year geoscience modules require understanding of 3-D spatial relationships, often from initial 2-D observations (e.g. mineralogy, petrography, vulcanology, sedimentology, palaeontology, geological map work, structural geology and fieldwork). In this paper we outline work, supported by the UK Subject Centre for Geography, Earth and Environmental Sciences (GEES), involving first year geosciences students at Liverpool, in which we explored
Arinilhaq,; Widita, Rena [Department of Physics, Nuclear Physics and Biophysics Research Group, Institut Teknologi Bandung (Indonesia)
2014-09-30
Optical Coherence Tomography is often used in medical image acquisition to diagnose that change due easy to use and low price. Unfortunately, this type of examination produces a two-dimensional retinal image of the point of acquisition. Therefore, this study developed a method that combines and reconstruct 2-dimensional retinal images into three-dimensional images to display volumetric macular accurately. The system is built with three main stages: data acquisition, data extraction and 3-dimensional reconstruction. At data acquisition step, Optical Coherence Tomography produced six *.jpg images of each patient were further extracted with MATLAB 2010a software into six one-dimensional arrays. The six arrays are combined into a 3-dimensional matrix using a kriging interpolation method with SURFER9 resulting 3-dimensional graphics of macula. Finally, system provides three-dimensional color graphs based on the data distribution normal macula. The reconstruction system which has been designed produces three-dimensional images with size of 481 × 481 × h (retinal thickness) pixels.
Sebastian E. Dunda
2012-01-01
Full Text Available The creation of musculoskeletal tissue represents an alternative for the replacement of soft tissue in reconstructive surgery. However, most of the approaches of creating artificial tissue have their limitations in the size as the maximally obtainable dimension of bioartificial tissue (BAT is limited due to the lack of supporting vessels within the 3-dimensional construct. The seeded myoblasts require high amounts of perfusion, oxygen, and nutrients to survive. To achieve this, we developed a 3-dimensional scaffold which features the epigastric artery as macroscopic core vessel inside the BAT in a rat model (perfused group, =4 and a control group (=3 without the epigastric vessels and, therefore, without perfusion. The in vivo monitoring of the transplanted myoblasts was assessed by bioluminescence imaging and showed both the viability of the epigastric artery within the 3-dimensional construct and again that cell survival in vivo is highly depending on the blood supply with the beginning of capillarization within the BAT seven days after transplantation in the perfused group. However, further studies focussing on the matrix improvement will be necessary to create a transplantable BAT with the epigastric artery as anastomosable vessel.
ZHONG Yan-lin; WANG You; WANG Hai-peng; RONG Ke; XIE Le
2011-01-01
Objective: To create a 3-dimensional finite element model of knee ligaments and to analyse the stress changes of lateral collateral ligament (LCL) with or without displaced movements at different knee flexion conditions.Methods: A four-major-ligament contained knee specimen from an adult died of skull injury was prepared for CT scanning with the detectable ligament insertion footprints,locations and orientations precisely marked in advance. The CT scanning images were converted to a 3-dimensional model of the knee with the 3-dimensional reconstruction technique and transformed into finite element model by the software of ANSYS. The model was validated using experimental and numerical results obtained by other scientists.The natural stress changes of LCL at five different knee flexion angles (0°, 30°, 60°, 90°, 120°) and under various motions of anterior-posterior tibial translation, tibial varus rotation and internal-external tibial rotation were measured.Results: The maximum stress reached to 87%-113%versus natural stress in varus motion at early 30° of knee flexions. The stress values were smaller than the peak value of natural stress at 0° (knee full extension) when knee bending was over 60° of flexion in anterior-posterior tibial translation and internal-external rotation.Conclusion: LCL is vulnerable to varus motion in almost all knee bending positions and susceptible to anterlor-posterior tibial translation or internal-external rotation at early 30° of knee flexions.
Neutron spectra calculation in material in order to compute irradiation damage
This short presentation will be on neutron spectra calculation methods in order to compute the damage rate formation in irradiated structure. Three computation schemes are used in the French C.E.A.: (1) 3-dimensional calculations using the line of sight attenuation method (MERCURE IV code), the removal cross section being obtained from an adjustment on a 1-dimensional transport calculation with the discrete ordinate code ANISN; (2) 2-dimensional calculations using the discrete ordinates method (DOT 3.5 code), 20 to 30 group library obtained by collapsing the 100 group a library on fluxes computed by ANISN; (3) 3-dimensional calculations using the Monte Carlo method (TRIPOLI system). The cross sections which originally came from UKNDL 73 and ENDF/B3 are now processed from ENDF B IV. (author)
Tamura, Masaya; Maekawa, Fujio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment
2003-03-01
Evaluation of shielding performance for a 1 MW spallation neutron source facility in the Materials and Life Science Facility being constructed in the High-Intensity Proton Accelerator Project (J-PARC) is important from a viewpoint of radiation safety and optimization of arrangement of components. This report describes evaluated results for the shielding performance with modeling three-dimensionally whole structural components including gaps between them in detail. A Monte Carlo calculation method with MCNPX2.2.6 code and LA-150 library was adopted. Streaming and void effects, optimization of shield for cost reduction and optimization of arrangement of structures such as shutters were investigated. The streaming effects were investigated quantitatively by changing the detailed structure of components and gap widths built into the calculation model. Horizontal required shield thicknesses were ranged from about 6.5 m to 7.5 m as a function of neutron beam line angles. A shutter mechanism for a horizontal neutron reflectometer that was directed downward was devised, and it was shown that the shielding performance of the shutter was acceptable. An optimal biological shield configuration was finally determined according to the calculated results. (author)
Dispersion of sulphur in the northern hemisphere. A study with a 3-dimensional time-resolved model
Tarrason, L.
1995-12-31
This thesis on atmospheric dispersion of sulphur presents a calculation of intercontinental transport of oxidized sulphur and allocates different contributions to sulphur background levels over Europe. It is found that a significant fraction of anthropogenic sulphur (AS) is transported out of continental boundaries thus affecting the background levels over major parts of the northern hemisphere. Over Europe, the contribution of AS from North America is similar in amount to that of Asian AS and natural sources from the North Atlantic Ocean. Although the yearly contribution of intercontinental transport to deposition of sulphur over Europe is quite small, it can be much more important over certain areas and seasons and is comparable to the contributions from individual European countries. The calculations are based on a three-dimensional Eulerian time-resolved model that describes sulphur dispersion in the atmosphere in connection with large-scale synoptic flows and agree well with observations. The thesis emphasizes the role of synoptic scale atmospheric motions in determining intercontinental transport of sulphur. It indicates the need to resolve individual cyclones and anticyclones in order to describe the dispersion and distribution of atmospheric sulphur in the northern hemisphere and stresses the value of comparing model calculations with observations, both in atmospheric chemistry studies and in climate applications. 260 refs., 50 figs., 17 tabs.
PWR or LMFBR cores or fuel assemblies, PWR steam generators, tubular heat exchangers, are as many components of a nuclear power plant involving single or two-phase flows in tube bundles. The knowledge of the detailed flow patterns (velocity, pressure, temperature, void fraction) on the shell side is necessary to evaluate DNB in reactor cores during incidental transients, singularity effects (grids, wire spacers, support plates, baffles), corrosion on steam generator tube sheet, bypass effects and vibration risks. For that purpose, the Research and Studies Branch of EDF is now developing a new 3D computer code THYC, at first for PWR's and LFMBR's core thermalydraulic calculations and in a second place, for more general applications of flows in tube bundles, thanks to a general porous medium approach. This paper describes the physical model used in THYC (4 partial differential equations, closure relationships specific of tube bundle geometries) then numerical solution method (space and time discretization, solution algorithm). Examples of numerical tests and incidental operation transients in a french PWR 900 MW core, are given. Finally, 3 validation calculations will be presented concerning a tube and shell heat exchanger, a LMFBR fuel assembly in natural, mixed and forced convection, and a lower part of a PWR steam generator
Megyesi, Joseph F.; Costello, Penny; McDonald, Warren; Macdonald, David; Easaw, Jay
2014-01-01
BACKGROUND: (blind field). METHODS: Records for patients treated for newly diagnosed or recurrent glioblastoma were analyzed. All patients had undergone surgical resection and tumor specimens at time of surgery were available for culture in a 3-dimensional matrix assay and observed for growth and invasion. Drug effects on mean invasion and growth were expressed as a ratio relative to control conditions. Length of survival was compared between temozolomide treated patients whose screening results had predicted a positive or negative response to temozolomide. The MGMT status of a subgroup of these patients was analyzed and correlated with the response of tumor tissue in the assay to temozolomide. RESULTS: Fifty-eight patients with glioblastoma were assessed. Each patient's tumor displayed a unique invasion and response profile. We looked in particular at the correlation between the outcome of a patient with glioblastoma treated with temozolomide and the response of that patient's tumor tissue to temozolomide in the 3-dimensional assay. Mean survival time for patients whose tumors were not significantly sensitive to temozolomide in the assay was 181.7 +/- 43 days. Mean survival time for patients whose tumors were significantly sensitive to temozolomide in the assay was 290.0 +/- 33 days. Twelve patients underwent MGMT testing. In 10 of the 12 patients there was a correlation between tumor response in the assay and MGMT status. CONCLUSIONS: The 3-dimensional assay may help predict glioblastoma patients who will show a treatment response to temozolomide. There appears to be a positive correlation between the response profiles in the assay to the MGMT status of the patient's tumor. SECONDARY CATEGORY: n/a.
Wright, K E; MacRobert, A J; Phillips, J. B.
2008-01-01
The effect of photodynamic therapy (PDT) on the cells of the nervous system is an important consideration in the treatment of tumours that are located within or adjacent to the brain, spinal cord and peripheral nerves. Previous studies have reported the sparing of nerves during PDT using meta-tetrahydroxyphenylchlorin (mTHPC, Foscan®) in patients and in animal models. The aim of this study was to investigate the effects of mTHPC on key nervous system cells using a 3-dimensional cell culture s...
Zubov, V.A.; Rozanov, E.V. [Main Geophysical Observatory, St.Petersburg (Russian Federation); Schlesinger, M.E.; Andronova, N.G. [Illinois Univ., Urbana-Champaign, IL (United States). Dept. of Atmospheric Sciences
1997-12-31
The problems of ozone depletion, climate change and atmospheric pollution strongly depend on the processes of production, destruction and transport of chemical species. A hybrid transport scheme was developed, consisting of the semi-Lagrangian scheme for horizontal advection and the Prather scheme for vertical transport, which have been used for the Atmospheric Chemical Transport model to calculate the distributions of different chemical species. The performance of the new hybrid scheme has been evaluated in comparison with other transport schemes on the basis of specially designed tests. The seasonal cycle of the distribution of N{sub 2}O simulated by the model, as well as the dispersion of NO{sub x} exhausted from subsonic aircraft, are in a good agreement with published data. (author) 8 refs.
1 - Description of program or function: The DOORS3.2a discrete ordinates transport code system includes the most recent versions of CCC-0543/TORT-DORT, CCC-0254/ANISN-ORNL, CCC-0628/GBANISN and CCC-0351/FALSTF. It also includes the ISOPLOT code from the PSR-0155/DOGS package and various utility programs listed below which were previously included in the TORT-DORT package. In this release each module is a separate executable file. Several modules, as needed, can be run in a single job by using 'jdos' to call the 'drv' module which interprets the sequence specified in the input. TORT calculates the flux of fluence of particles due to particles incident upon the system from extraneous sources or generated internally as a result of interaction with the system in two-or three-dimensional geometric systems, and DORT is used in one- or two-dimensional geometric systems. The principle application is to the deep-penetration transport of neutrons and photons. Reactor eigenvalue problems can also be solved. Numerous printed edits of the results are available, and results can be transferred to output files for subsequent analysis. ANISN solves the one-dimensional Boltzmann transport equation for neutrons or gamma rays in slab, spherical, or cylindrical geometry. GBANISN is based on ANISN but was modified to allow randomizing of multi-bank fluxes within a group at all interfaces between dissimilar materials and a reduction in the number of outer iterations for problems involving neutron up-scatter into higher energy groups. GBANISN requires fewer outer iterations than ANISN by performing 'inner iterations' over energy groups within a 'band' and converging those groups before moving to the next band. These 'inner' iterations slightly resemble outer iterations in ANISN. Thus, a calculation with up-scatter and no fission can be solved with one traditional outer iteration. GBANISN, like ANISN, includes a technique for handling general anisotropic scattering, pointwise convergence
Purpose: We reviewed our institution's experience treating patients with nonpalpable PSA-detected prostate cancer with three-dimensional conformal radiation therapy (3DCRT) to determine prognostic factors that predict for biochemical-free survival (bNED) control and present the bNED control rates. Methods and Materials: Between May 1, 1990 and November 30, 1994, 160 patients with nonpalpable PSA-detected prostate cancer received 3DCRT at Fox Chase Cancer Center (median total dose 73 Gy; range: 67-78 Gy). bNED failure was defined as three consecutive increases in posttreatment PSA after achieving a nadir. bNED failure was recorded as the time midway between the nadir and the first consecutive rising PSA. Five-year actuarial rates of bNED control were calculated for pretreatment PSA (0-9.9 vs. 10-19.9 vs. ≥ 20 ng/ml), Gleason score (2-6 vs. 7-10), treatment field size (prostate vs. small pelvis), age (73 Gy) using Kaplan-Meier methods and compared using the Log rank test. The Cox model was used to multivariately establish independent predictors based on significant univariate factors. Median follow-up was 39 months (range: 2-84 months). Results: The 5-year actuarial rate of bNED control was 86% for the entire group of patients. The Cox Proportional Hazards model demonstrated that pretreatment PSA was an independent predictor of bNED control. Treatment field size was marginally predictive. There was no difference in bNED control when patients were stratified by the number of lobes positive for disease. Statistically different rates of bNED control were seen when the patients with nonpalpable disease were univariately compared to T2b and T2c patients. Three patients experienced Grade 3-4 genitourinary (GU) toxicity and 3 patients experienced Grade 3-4 gastrointestinal (GI) toxicity. Conclusions: Patients with nonpalpable PSA-detected prostate cancer can be effectively treated with 3DCRT with minimal morbidity and high rates of bNED control at 5 years. Pretreatment
TriTel 3 dimensional space dosimetric telescope in the European Student Earth Orbiter project of ESA
Zábori, Balázs; Hirn, Attila
2012-02-01
The development of the European Student Earth Orbiter (ESEO) was announced in the year of 2008 by the European Space Agency for students interested in the space exploration. The Budapest University of Technology and Economics joined this international cooperation with three student groups among other participating European universities. One of them is the ESEO-TriTel team. The development of the TriTel 3D silicon detector telescope began in the KFKI Atomic Energy Research Institute several years ago in order to determine the average radiation quality factor of the space radiation field for dosimetric purposes. In the year 2011—before the start of the ESEO mission—it will be operated on board the European Columbus module of the International Space Station (ISS) and will be installed in the Russian segment of the ISS as well. The ESEO version of TriTel will fly higher than the ISS version, at an altitude of 520 km. At this altitude the Earth's geomagnetic field is much lower and the spectrum of the radiation field is also different. In the ESEO-TriTel experiment the anisotropies in the radiation field, the effects of the Earth shadow and the South Atlantic Anomaly (SAA) will be analysed and the results will be compared with the fluxes calculated with the standard AP-8 and AE-8 trapped proton and electron models. In the near future the frequency of manned space flights will probably increase, we can think of the continuous human presence in the near-Earth region (low Earth orbits) or the proposed human Mars expedition. That is why the cosmic radiation field is interesting not only in the near-Earth region but at higher altitudes or in the interplanetary field as well. The present paper addresses the optimal shielding of the dosimetric telescopes of TriTel in order to avoid the saturation of the electronics. The amount of optimal shielding is equivalent to the effective thickness of astronaut's space suit, which means that the same dose will be measured as what the
(target), were analyzed using a 3D treatment planning system. Results: The variation in treatment portals of the national study appeared to be quite substantial, resulting in large differences in treated volumes, calculated normal tissue complication probabilities (NTCP) and tumor control probabilities (TCP). The four ROs mastered the delineation of the lymphnodal regions on the CT-slices relatively easy; they were able to outline the regions on every CT-slice (5 mm slices) of the whole neck within 2 hours. The variation in delineated areas was generally well within 1 cm. Furthermore, it is of interest that for the same patient that was used in the nation wide inventory, ENI treatment portals designed using BEV, based on our CT target definition protocol, allowed for significant sparing of the major salivary glands. Conclusion: The present studies have resulted in a well defined, reproducible protocol for the delineation of lymphnodal regions (1-6) in the neck on CT-slices. Using these CT-region definitions allows for standardization of neck portals. This protocol can be of particular use in elective neck irradiation (N0 neck; limited doses of 40-50 Gy), or in case of N+ neck for which a neck dissection combined with neck irradiation to a dose of approximately 50 Gy is considered appropriate treatment. Further improvement is anticipated (work in progress) by using these CT-region definitions in 3DCRT
On-Site was developed to provide modelers and model reviewers with prepackaged tools ("calculators") for performing site assessment calculations. The philosophy behind OnSite is that the convenience of the prepackaged calculators helps provide consistency for simple calculations,...
Lambros, Maria P; DeSalvo, Michael K; Moreno, Jonathan; Mulamalla, Hari Chandana; Kondapalli, Lavanya
2015-12-01
Cancer patients who receive radiation are often afflicted by oral mucositis, a debilitating disease, characterized by mouth sores and difficulty in swallowing. Oftentimes, cancer patients afflicted with mucositis must stop life-saving therapies. Thus it is very important to prevent mucositis before it develops. Using a validated organotypic model of human oral mucosa, a 3-dimensional cell culture model of human oral keratinocytes, it has been shown that a mixture (NAC-QYD) of N-acetyl cysteine (NAC) and a traditional Chinese medicine, Qingre Liyan decoction (QYD), prevented radiation damage (Lambros et al., 2014). Here we provide detailed methods and analysis of microarray data for non-irradiated and irradiated human oral mucosal tissue with and without pretreatment with NAC, QYD and NAC-QYD. The microarray data been deposited in Gene Expression Omnibus (GEO): GSE62397. These data can be used to further elucidate the mechanisms of irradiation damage in oral mucosa and its prevention. PMID:26697327
Maria P. Lambros
2015-12-01
Full Text Available Cancer patients who receive radiation are often afflicted by oral mucositis, a debilitating disease, characterized by mouth sores and difficulty in swallowing. Oftentimes, cancer patients afflicted with mucositis must stop life-saving therapies. Thus it is very important to prevent mucositis before it develops. Using a validated organotypic model of human oral mucosa, a 3-dimensional cell culture model of human oral keratinocytes, it has been shown that a mixture (NAC–QYD of N-acetyl cysteine (NAC and a traditional Chinese medicine, Qingre Liyan decoction (QYD, prevented radiation damage (Lambros et al., 2014. Here we provide detailed methods and analysis of microarray data for non-irradiated and irradiated human oral mucosal tissue with and without pretreatment with NAC, QYD and NAC-QYD. The microarray data been deposited in Gene Expression Omnibus (GEO: GSE62397. These data can be used to further elucidate the mechanisms of irradiation damage in oral mucosa and its prevention.
To evaluate a comprehensive magnetic resonance imaging (MRI) protocol as noninvasive diagnostic modality for simultaneous detection of parenchymal, biliary, and vascular complications after liver transplantation. Fifty-two liver transplant recipients suspected to have parenchymal, biliary, and (or) vascular complications underwent our MRI protocol at 1.5T unit using a phased array coil. After preliminary acquisition of axial T1w and T2w sequences, magnetic resonance cholangiography (MRC) was performed through a breath-hold, thin- and thick-slab, single-shot T2w sequence in the coronal plane. Contrast-enhanced magnetic resonance angiography (CEMRA) was obtained using a 3-dimensional coronal spoiled gradient-echo sequence, which enabled acquisition of 32 partitions 2.0 mm thick. A fixed dose of 20 ml gadobenate dimeglumine was administered at 2 mL/s. A post-contrast T1w sequence was also performed. Two observers in conference reviewed source images and 3-dimensional reconstructions to determine the presence of parenchymal, biliary, and vascular complications. MRI findings were correlated with surgery, endoscopic retrograde cholangiography (ERC), biopsy, digital subtraction angiography (DSA), and imaging follow-up. MRI revealed abnormal findings in 32 out of 52 patients (61%), including biliary complications (anastomotic and nonanastomotic strictures, and lithiasis) in 31, vascular disease (hepatic artery stenosis and thrombosis) in 9, and evidence of hepatic abscess and hematoma in 2. ERC confirmed findings of MRC in 30 cases, but suggested disease underestimation in 2. DSA confirmed 7 magnetic resonance angiogram (MRA) findings, but suggested disease overestimation in 2. MRI combined with MRC and CEMRA can provide a comprehensive assessment of parenchymal, biliary, and vascular complications in most recipients of liver transplantation. (author)
Boraschi, P.; Donati, F.; Gigoni, R. [Pisa Univ. Hospital, Second Dept. of Radiology, Pisa (Italy)], E-mail: p.boraschi@do.med.unipi.it; Salemi, S. [Univ. of Pisa, Diagnostic and Interventional Radiology, Pisa (Italy); Urbani, L.; Filipponi, F. [Univ. of Pisa, Liver Transplant Unit of the Dept. of Oncology, Transplants and Advanced Technologies in Medicine, Pisa (Italy); Falaschi, F. [Pisa Univ. Hospital, Second Dept. of Radiology, Pisa (Italy); Bartolozzi, C. [Univ. of Pisa, Diagnostic and Interventional Radiology, Pisa (Italy)
2008-12-15
To evaluate a comprehensive magnetic resonance imaging (MRI) protocol as noninvasive diagnostic modality for simultaneous detection of parenchymal, biliary, and vascular complications after liver transplantation. Fifty-two liver transplant recipients suspected to have parenchymal, biliary, and (or) vascular complications underwent our MRI protocol at 1.5T unit using a phased array coil. After preliminary acquisition of axial T{sub 1}w and T{sub 2}w sequences, magnetic resonance cholangiography (MRC) was performed through a breath-hold, thin- and thick-slab, single-shot T{sub 2}w sequence in the coronal plane. Contrast-enhanced magnetic resonance angiography (CEMRA) was obtained using a 3-dimensional coronal spoiled gradient-echo sequence, which enabled acquisition of 32 partitions 2.0 mm thick. A fixed dose of 20 ml gadobenate dimeglumine was administered at 2 mL/s. A post-contrast T{sub 1}w sequence was also performed. Two observers in conference reviewed source images and 3-dimensional reconstructions to determine the presence of parenchymal, biliary, and vascular complications. MRI findings were correlated with surgery, endoscopic retrograde cholangiography (ERC), biopsy, digital subtraction angiography (DSA), and imaging follow-up. MRI revealed abnormal findings in 32 out of 52 patients (61%), including biliary complications (anastomotic and nonanastomotic strictures, and lithiasis) in 31, vascular disease (hepatic artery stenosis and thrombosis) in 9, and evidence of hepatic abscess and hematoma in 2. ERC confirmed findings of MRC in 30 cases, but suggested disease underestimation in 2. DSA confirmed 7 magnetic resonance angiogram (MRA) findings, but suggested disease overestimation in 2. MRI combined with MRC and CEMRA can provide a comprehensive assessment of parenchymal, biliary, and vascular complications in most recipients of liver transplantation. (author)
Galland-Girodet, Sigolène; Pashtan, Itai; MacDonald, Shannon M.; Ancukiewicz, Marek [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Hirsch, Ariel E.; Kachnic, Lisa A. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Department of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts (United States); Specht, Michelle; Gadd, Michele; Smith, Barbara L. [Department of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Powell, Simon N. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Recht, Abram [Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts (United States); Taghian, Alphonse G., E-mail: ataghian@partners.org [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States)
2014-11-01
Purpose: To present long-term outcomes of a prospective feasibility trial using either protons or 3-dimensional conformal photon-based (accelerated partial-breast irradiation [APBI]) techniques. Methods and Materials: From October 2003 to April 2006, 98 evaluable patients with stage I breast cancer were treated with APBI (32 Gy in 8 fractions given twice daily) on a prospective clinical trial: 19 with proton beam therapy (PBT) and 79 with photons or mixed photons/electrons. Median follow-up was 82.5 months (range, 2-104 months). Toxicity and patient satisfaction evaluations were performed at each visit. Results: At 7 years, the physician rating of overall cosmesis was good or excellent for 62% of PBT patients, compared with 94% for photon patients (P=.03). Skin toxicities were more common for the PBT group: telangiectasia, 69% and 16% (P=.0013); pigmentation changes, 54% and 22% (P=.02); and other late skin toxicities, 62% and 18% (P=.029) for PBT and photons, respectively. There were no significant differences between the groups in the incidences of breast pain, edema, fibrosis, fat necrosis, skin desquamation, and rib pain or fracture. Patient-reported cosmetic outcomes at 7 years were good or excellent for 92% and 96% of PBT and photon patients, respectively (P=.95). Overall patient satisfaction was 93% for the entire cohort. The 7-year local failure rate for all patients was 6%, with 3 local recurrences in the PBT group (7-year rate, 11%) and 2 in photon-treated patients (4%) (P=.22). Conclusions: Local failure rates of 3-dimensional APBI and PBT were similar in this study. However, PBT, as delivered in this study, led to higher rates of long-term telangiectasia, skin color changes, and skin toxicities. We recommend the use of multiple fields and treatment of all fields per treatment session or the use of scanning techniques to minimize skin toxicity.
Purpose: To present long-term outcomes of a prospective feasibility trial using either protons or 3-dimensional conformal photon-based (accelerated partial-breast irradiation [APBI]) techniques. Methods and Materials: From October 2003 to April 2006, 98 evaluable patients with stage I breast cancer were treated with APBI (32 Gy in 8 fractions given twice daily) on a prospective clinical trial: 19 with proton beam therapy (PBT) and 79 with photons or mixed photons/electrons. Median follow-up was 82.5 months (range, 2-104 months). Toxicity and patient satisfaction evaluations were performed at each visit. Results: At 7 years, the physician rating of overall cosmesis was good or excellent for 62% of PBT patients, compared with 94% for photon patients (P=.03). Skin toxicities were more common for the PBT group: telangiectasia, 69% and 16% (P=.0013); pigmentation changes, 54% and 22% (P=.02); and other late skin toxicities, 62% and 18% (P=.029) for PBT and photons, respectively. There were no significant differences between the groups in the incidences of breast pain, edema, fibrosis, fat necrosis, skin desquamation, and rib pain or fracture. Patient-reported cosmetic outcomes at 7 years were good or excellent for 92% and 96% of PBT and photon patients, respectively (P=.95). Overall patient satisfaction was 93% for the entire cohort. The 7-year local failure rate for all patients was 6%, with 3 local recurrences in the PBT group (7-year rate, 11%) and 2 in photon-treated patients (4%) (P=.22). Conclusions: Local failure rates of 3-dimensional APBI and PBT were similar in this study. However, PBT, as delivered in this study, led to higher rates of long-term telangiectasia, skin color changes, and skin toxicities. We recommend the use of multiple fields and treatment of all fields per treatment session or the use of scanning techniques to minimize skin toxicity
NONE
1999-03-01
For the formation of cellular tissues to replace bionic tissues, researches were conducted about technologies of forming bionic tissue modules by culturing various kinds of cells. As for the materials and methods for constructing cellular tissues, researches were conducted about the trends of research and development of 3-dimensional tissue culturing matrices and materials for micromanipulation. As for the development of technologies for the functionalization of 3-dimensionally structured cells, research and study were conducted about the technology of 3-dimensional cell structure organization through application of physical stimulation, the biochemical technology of differentiation inducing, and the differentiation inducing technology for hetero tissue culturing. As for the development of technologies for evaluation using 3-dimensionally structured cells, light CT (computer tomography), analysis and evaluation using spectroscopy and the like, feasibility of the biochemical analysis of the cell state using biosensors, technologies for measuring the secretion of carcinogenic and toxic substances, etc., were studied. In addition, the development of organic models to replace test animals, industrial evolution of 3-dimensional tissue module engineering, etc., were investigated. (NEDO)
A point-kernel integral technique code, PKN, and the related data library have been developed to calculate neutron and secondary gamma-ray dose equivalents in water, concrete and iron shields for neutron sources in 3-dimensional geometry. The comparison between calculational results of the present code and those of the 1-dimensional transport code ANISN = JR, and the 2-dimensional transport code DOT4.2 showed a sufficient accuracy, and the availability of the PKN code has been confirmed. (author)