A thermal-electric mathematical model for a squirrel cageinductionmotors which permits to specify the best motor for specific drive, under thermal and electric aspects based, only on manufacturer technical bulletins and technical information is presented. Changes of rotor parameters due Skin Effect and changes of winding resistances (both stator and rotor) with the temperature are considered. The accuracy of this model is appraised using experimental results. The thermal behavior and electric performance for some motors are obtained for continuos and intermittent duties with sinusoidal and non-sinusoidal voltages. (author)
The use of an SCR-controlled power system on an offshore drilling rig has lead to an increased acceptance of high technology equipment. Such equipment increases drilling productivity, reduces maintenance, and improves reliability. Most new rigs now have AC squirrel cagemotors, brushless AC generators, silicon controlled rectifiers, DC motors, and swtichgear and motor starters. Several opportunities for cost reductions in SCR systems, such as improving the power factor, are studied in this paper.
An overview of the developments and designs of electric cars is given. It can be concluded that the numbers of electric-powered vehicles in the world, presented by different companies, are confusing and that it is very difficult to categorize the electric cars because of the many different prototypes under development sofar. Also an introduction is given on the engine technology of such cars. Attention is paid to the direct current (DC) motor, the inductionmotor, the brushless DC-motor, and the synchronous motor. 2 figs., 4 ills., 35 refs.
This paper presents a new and simple method for sensorless control of matrix converter drives using a power flowing to the motor. The proposed control algorithm is based on controlling the instantaneous real and imaginary powers into the inductionmotor. To improve low-speed sensorless performance, the nonlinearities of a matrix converter drive such as commutation delays, turn-ON and turn-OFF times of switching devices, and on-state switching device voltage drop are modeled using a PQ power transformation and compensated using a reference power control scheme. The proposed sensorless control method is applied for the inductionmotor drive using a 3 kW matrix converter system. Experimental results are shown to illustrate the feasibility of the proposed strategy. Udgivelsesdato: September
This paper proposes a novel control strategy for tracking peak power in a wind or wave energy system using a squirrel cageinduction generator. It eliminates wind speed measurement or estimation and uses a simple scalar technique by exploiting the cubic nature of the power curve. The method works even when air velocity is varying dynamically. (author)
This paper presents a technique for speed control three-phase inductionmotor using the pulse width modulation (PWM), in open loop while maintaining the tension for constant frequency. The technique is adapted from a thesis entitled 'Control of the three-phase inductionmotor, using discrete PWM generation, optimized and synchronized', where studies are presented aimed at their application in home appliances, to eliminate mechanical parts, replaced by low cost electronic control, thus having a significant reduction in power consumption. Initially the experiment was done with the Intel 80C31 micro controller. In this paper, the PWM modulation is implemented using a PIC micro controller, and the speed control kept a low profile, based on tables, synchronized with transitions and reduced generation of harmonics in the network. Confirmations were made using the same process of building ...
A totally-enclosed, fan-cooled, rib-cooled type inductionmotor is adopted for an exhauster which is to be installed in a ventilation station for dust catcher in a tunnel. It has the highest capacity in Japan for the above purpose, and is provided with a cooling fan inside to recirculate cooled air, thereby improving cooling efficiency and reducing size and weight. Three-row combined angular ball bearings are used as the thrust bearings, and grease lubrication system is adopted to simplify the inspection/maintenance works. It is to be delivered to Japan Highway Public Corporation's Shizuoka Construction Bureau, Yaizu site office. Its electric specifications are 455 kW, 440 V, 890 A and 510 rpm, and its mechanical specifications are thrust load: 16 kN and impeller load: 7.2 kN. (translated by NEDO)
The laboratory environment existing outside the test situation itself can have a substantial influence on results of some behavioral tests with mice, and the extent of these influences sometimes depends on genotype. For alcohol research, the principal issue is whether genotype-related ethanol effects will themselves be altered by common variations in the lab environment or instead will be essentially the same across a wide range of lab environments. Data from 20 inbred strains were used to reduce an original battery of seven tests of alcohol intoxication to a compact battery of four tests: the balance beam and grip strength with a 1.25g/kg ethanol dose and the accelerating rotarod and open-field activation tests with 1.75g/kg. The abbreviated battery was then used to study eight inbred str...
Background Identifying susceptibility genes for endophenotypes by studying analogous behaviors across species is an important strategy for understanding the pathophysiology underlying psychiatric disorders. This approach provides novel biological pathways plus validated animal models critical for selective drug development. One such endophenotype is avoidance behavior. Methods In the present study, novel automated registration methods for longitudinal behavioral assessment in home cages are used to screen a panel of recently generated mouse chromosome substitution strains that are very powerful in quantitative trait loci (QTL) detection of complex traits. In this way, we identified chromosomes regulating avoidance behavior (increased sheltering preference) independent of motor activity lev...
The activity of mice in their home cage is influenced greatly by the cycle of light and dark. In addition, home-cage activity shows remarkable time-dependent changes that result in a prominent temporal...Full Text Available
The Segmented Rail Phased InductionMotor (SERAPHIM) is a compact, pulsed linear inductionmotor (LIM) offering a unique capability for very high speed train propulsion. It uses technology developed for the Sandia coilgun, an electromagnetic launcher designed to accelerate projectiles to several kilometers per second. Both aluminum cylinders and plates were accelerated to a kilometer per second (Mach 3) by passing through a sequence of coils which were energized at the appropriate time. Although this technology was developed for ultra-high velocity, it can be readily adapted to train propulsion for which, at sea level, the power required to overcome air resistance limits the operational speed to a more modest 300 mph. Here, the geometry is reversed. The coils are on the vehicle and the ``projectiles`` are fixed along the roadbed. SERAPHIM operates not by embedding flux in a conductor, but by excluding ...
Generalized dynamic motion of balls and cage in a ball bearing are simulated by solving the differential equations of motion under prescribed operating conditions and bearing geometry. The general cage motion is parametrically evaluated as a function of clearances both in the ball pockets and at the guide lands. The design significance of the modeling approach is demonstrated by the prediction of critical clearances which trigger certain instabilities in the cage motion. In more practical terms, the correlation between cage clearances and instability defines a wear life for the bearing under the prescribed operating conditions. 10 refs.
Field cage studies were carried out to evaluate the F_1 sterility technique for population suppression of the pink bollworm, Pectinophora gossypiella (Saunders), in cotton. For this purpose, six field cages (1.8 m x 1.8 m x 1.8 m) were placed over cotton seedlings in the field. Five pairs of laboratory reared, untreated adult moths were released in all six cages during the first week of August. In addition, on the same data 100 pairs of adults, following irradiation of the mature pupae at 100 Gy, were released in two cages and 250 such pairs of irradiated adults in two other cages in ratios of 20:1 and 50:1 (irradiated:normal), respectively. The results of per cent larval infestation in the rosette blooms in different field cages indicated that larval infestation in the flowers was significantly lower (4.93%) in cages where the moths were ...
This paper presents a new method to improve sensorless performance of matrix converter drives using a parameter estimation scheme. To improve low-speed sensorless performance, the non-Iinearities of a matrix converter drive such as commutation delays, turn-on and turn-off times of switching devices, and on-state switching device voltage drop is modelled using PQR transformation and compensated using a reference current control scheme. To eliminate the input current distortion due to the input voltage unbalance, a simple method using PQR transformation is also presented. The proposed compensation method is applied for high performance inductionmotor drives using a 3 kW matrix converter system without a speed sensor. Experimental results are shown to illustrate the feasibility of the proposed strategy.
This paper presents a new method to compensate the nonlinearities for matrix converter drives. The nonlinearities of matrix converter drives such as commutation delay, turn-on and turn-off time of the switching devices, and on-state switching device voltage drop is corrected by a new matrix converter model using the direction of current. The proposed method does not need any additional hardware or complicated software and it is easy to realize by applying the algorithm to the conventional vector control. The proposed compensation method is applied for high-performance inductionmotor drives using a 3-kW matrix converter system without a speed sensor. Experimental results show the proposed method provides good compensating characteristics.
Development status of small direct injection diesel engine at Isuzu Motors Ltd. is reviewed. There is much difficulty in combustion optimization of small DI engines, due to small combustion chamber volume, large surface to volume ratio, wide engine speed range and so on. Novel ideas in the area of injection system, combustion chamber and induction swirl were tried to solve these problems and their effects are presented here. Our prototype DI engines which adopted some of these ideas has turned out to have better fuel economy by about 15 percent, 2 - 3 dB(A) higher noise level than IDI and almost the same power output performance as IDI. As to exhaust emissions, they have a possibility to conform to '86 California emission standards, in inertia weight classes up to 2625 LBS. The remaining problem areas are noise emission, durability of injection pump and cabin heater performance. These problems must be solved by further innovation, ...
A few papers have been interested by the fixed switching frequency direct torque control fed by direct matrix converters, where we can find just the use of direct torque controlled space vector modulated method. In this present paper, we present an improved method used for a fixed switching frequency direct torque control (DTC) using a direct matrix converter (DMC). This method is characterized by a simple structure, a fixed switching frequency which causes minimal torque ripple and a unity input power factor. Using this strategy, we combine the direct matrix converters advantages with those of direct torque control (DTC) schemes. The used technique for constant frequency is combined with the input current space vector to create the switching table of direct matrix converter (DMC). Simulation results clearly demonstrate a better dynamic and steady state performances of the proposed method.
SummaryBackground Intracellular transport via processive kinesin, dynein, and myosin molecular motors plays an important role in maintaining cell structure and function. In many cases, cargoes move distances longer than expected for single motors; there is significant evidence that this increased travel is in part due to multiple motors working together to move the cargoes. Although we understand single motors experimentally and theoretically, our understanding of multiple motors working together is less developed. Results We theoretically investigate how multiple kinesin motors function. Our model includes stochastic fluctuations of each motor as it proceeds through its enzymatic cycle. Motors dynamically influence each other and function in the presence of thermal noise and viscosity. We...
Biological motors generally fall into two categories: (1) those that convert chemical into mechanical energy via hydrolysis of a nucleoside triphosphate, usually adenosine triphosphate, regarded as life's chemical currency of energy and (2) membrane bound motors driven directly by an ion gradient and/or membrane potential. Here we argue that electrostatic interactions play a vital role for both types of motors and, therefore, the tools of physics can greatly contribute to understanding biological motors.
For many years one of us has cooked on an induction cooktop and been impressed by its efficiency, cleanliness, and responsiveness. The commercial name ``induction'' cooktop suggests that we have here an application of Faraday's law of electromagnetic induction since the cooktop produces an oscillating magnetic field.
Variability in motor performance decreases with practice but is never entirely eliminated, due in part to inherent motor noise. The present study develops a method that quantifies how performers...Full Text Available
A novel soft commutated direct current (DC) motor is introduced. The current of the commutated coil is intentionally drained before the brush disconnects the coil. This prevents the spark generation that normally occurs in conventional DC motors. A similar principle can be applied for DC generators.
Motor function requires that motor axons extend from the spinal cord at regular intervals and that they are myelinated by Schwann cells. Little attention has been given to another cellular structure,...Full Text Available
Motivated by the discovery of superconductivity in alkali and alkaline earth fullerides, this program was undertaken both to understand the nature of and expand the range of materials demonstrating superconductivity. The first approach involved attempts to modify the fullerene cage by incorporating heteroatoms in the structure and the preparation and photophysical properties of nitrogen and sulfur doped fullerenes were studied in detail. The second approach involved examining the stoichiometry and effect of preparative conditions on the behavior of alkali, alkaline earth, lanthanide and mixed ion fullerides. In particular, the authors have elaborated on a technique for making such salts using liquid ammonia or aliphatic amines as solvents. Thirdly, modeling studies were undertaken to predict the properties of heterohedral fullerines and metal - C60 complexes, and theoretical guidelines were developed for understanding the reactivity of the fullerene ...
The total amount of uranium dissolved in seawater at a uniform concentration of 3 mg U/m{sup 3} in the world's oceans is 4.5 billion tons. An adsorption method using polymeric adsorbents capable of specifically recovering uranium from seawater is reported to be economically feasible. A uranium-specific nonwoven fabric was used as the adsorbent packed in an adsorption cage 16 m{sup 2} in cross-sectional area and 16 cm in height. We submerged three adsorption cages in the Pacific Ocean at a depth of 20 m at 7 km offshore of Japan. The three adsorption cages consisted of stacks of 52 000 sheets of the uranium-specific non-woven fabric with a total mass of 350 kg. The total amount of uranium recovered by the nonwoven fabric was >1 kg in terms of yellow cake during a total submersion time of 240 days in the ocean.
The total amount of uranium dissolved in seawater at a uniform concentration of 3 mg U/m3 in the world's oceans is 4.5 billion tons. An adsorption method using polymeric adsorbents capable of specifically recovering uranium from seawater is reported to be economically feasible. A uranium-specific nonwoven fabric was used as the adsorbent packed in an adsorption cage 16 m2 in cross-sectional area and 16 cm in height. We submerged three adsorption cages in the Pacific Ocean at a depth of 20 m at 7 km offshore of Japan. The three adsorption cages consisted of stacks of 52 000 sheets of the uranium-specific non-woven fabric with a total mass of 350 kg. The total amount of uranium recovered by the nonwoven fabric was >1 kg in terms of yellow cake during a total submersion time of 240 days in the ocean.
Direct current motors are used in photovoltaic systems. Important characteristics of electric motors are the starting to rated current and the torque ratios. These ratios are dictated by the size of the solar cell array and are different for the various dc motor types. The paper deals with the calculation of the starting to rated current ratio and starting to rated torque ratio of the permanent magnet, separately, series and shunt excited motors when powered by solar cells for the two cases: where (1) the system includes a maximum-power-point-tracker (MPPT) and (2) without an MPPT. Comparing these two cases, one gets a torque magnification of about 3 for the permanent magnet motor and about 7 for other motor types at rated design insolation. The calculation of the torques may assist the PV system designer to determine the advantage of including an MPPT in the ...
Brains are usually described as input/output systems: they transform sensory input into motor output. However, the motor output of brains (behavior) is notoriously variable, even under identical sensory...Full Text Available
Squeeze film dampers (SFD) are devices utilized to control vibrations of the shafts of high-speed rotating machinery. The SFD - squirrel cage combination is probably the most used system for tuning the stiffness and damping of the supports for rotors installed on ball bearings. Squeeze film dampers are essentially hydrodynamic bearings which contain the ball bearings housings of ball-bearings supported shafts. Consequently, the oil film within the SFD are influenced only by the precession and nutation of the shaft, that is the flow of the oil within the damper is not directly influenced by the spin of the rotor. However, in the classical theory, the flow in the thin film is also governed by the Reynolds equation. In this paper, some of the limits of the classical theory of the SFD are discussed and theoretical and experimental studies, which illustrate the ideas presented herein, are presented as well. The orbits of an unbalanced rotor that is supported by a ...
Experimentally it is shown that a movable grounded metallic plate placed inside a multi-dipole magnetic cage can vary the diffused plasma parameters such as density, plasma potential and electron temperature. Plasma is solely produced in the source section of a double plasma device by a dc hot filament discharge and a low-density plasma is produced in the target section by local ionization of neutral gas by the high energetic electrons coming from the source section. A grounded movable stainless steel plate is inserted in the target section of the device. The floating potential of the plate also changes depending on the position of the plate inside the magnetic cage.
The FIAT company in Brazil tested the use of biogas for combustion in otto cycle engines, both stationary and Not stationary, and proved that technically it is a good option in substitution of gasoline. The work presents the changes in the motor for biogas use and compares it with alcohol motors for power and consumption. 18 figs.
Cadmium is a non-essential heavy metal found abundantly in the environment. Children of women exposed to cadmium during pregnancy display lower motor and perceptual abilities. High cadmium body burden in children is also related to impaired intelligence and lowered school achievement. However, little is known about the molecular and cellular basis of developmental neurotoxicity in the sensitive early life stages of animals. In this study, we explore neurological deficits caused by cadmium during early embryonic stages in zebrafish by examining regionalization of the neural tube, pattern formation and cell fate determination, commitment of proneural genes and induction of neurogenesis. We show that cadmium-treated embryos developed a smaller head with unclear boundaries between the brain subdivisions, particularly in the mid-hindbrain region. Embryos display normal anterior to posterior regionalization; however, the commitment of neural ...
... the high current induction linear accelerator of the nanosecond range, meant to be used as injector in the collective ion accelerator, are presented. ...
Previous research has shown that SAR hotspots are induced within the laboratory rat and that the resulting thermal hotspots are not entirely dissipated by bloodflow. Two experiments were conducted to determine if hotspot formation in the body and tail of the rat, which is radiation frequency specific, would have behavioral consequences. In the first experiment rats were placed in a plexiglas cage one side of which, when occupied by the rat, commenced microwave radiation exposure; occupancy of the other side terminated exposure. Groups of rats were tested during a baseline period to determine the naturally preferred side of the cage. Subsequent exposure to 360-MHz, 700-MHz or 2450-MHz microwave radiation was made contingent on preferred-side occupancy. A significant reduction in occupancy of the preferred side of the cage, and hence, microwaves subsequently occurred. Reduced exposure to 360-MHz and 2450-MHz microwaves at 1, ...
MAGNETIC FORMING .............. MAGNETIC INDUCTION ............ MAGNETIC MATERIALS ............ MAGNETIC MEASUREMENT .......... MAGNETIC PERMEABILITY . ...
... The effectiveness of immune suppression with both 6-mercaptopurine and methotrexate was insufficient to permit induction of a clinically useful ...
The effects of selected ligands on the structure of the truncated heavy-chain chemomechanical motor domains of Drosophila ncd and human kinesin were compared using the technique of transient electric...Full Text Available
The neuronal networks in spinal cord can produce a diverse array of motor behaviors. In aquatic vertebrates such as fishes and tadpoles, these include escape behaviors, swimming across a range...Full Text Available
ObjectiveMusician's focal dystonia is usually considered to be task specific but secondary motor disturbances have been reported also. We carried out a detailed evaluation of the...Full Text Available
Health standards for truck drivers are higher than those for the general motoring public, particularly concerning the need to restrict driving following recovery from a myocardial infarction. An analysis...Full Text Available
Spinal cord injury (SCI) is a debilitating disorder, which produces profound deficits in volitional motor control. Following medical stabilization, recovery from SCI typically involves long term rehabilitation....Full Text Available
Blindness leads to a major reorganization of neural pathways associated with touch. Because incoming somatosensory information influences motor output, it is plausible that motor plasticity occurs in...Full Text Available
OBJECTIVE: To assess the motor function of the left, supposedly unaffected, limbs of patients with an acute right vascular hemiplegia. METHODS: Fifteen patients with an acute vascular right hemiplegia...Full Text Available
Proprioceptive sensory signals inform the CNS of the consequences of motor acts, but effective motor planning involves internal neural systems capable of anticipating actual sensory feedback....Full Text Available
Samples of austenitic stainless steel AISI 316 were nitrided using the cathodic cage technique with the addition of methane in the nitriding atmosphere. The aim was to study the influence of this technique in reducing the precipitation of chromium nitrite and in improving the wear resistance. The results show that there was a significant improvement in such properties when compared to the results of ionic plasma nitriding. Formation of a double layer, one more internal composed of carbon and another with high nitrogen content, was confirmed by Scanning Electron Microscopy (SEM). The microhardness profile of the layer showed an increase in hardness values and a larger uniformity, while X-ray analysis showed less chromium nitriding precipitation when compared with results obtained for samples treated using ionic plasma nitriding.
... is disengaged from the spent rocket motor by a ... of the outbound and incoming modu- ... meteorological sensor and reference resistor is accomplished ...
The effect of open pit mine motor transport with ICE on the air basin is examined using the example of shale mines and open pits of the production association ''Estonslanets''. Efficient areas of use of different types of open pit mine motor transport, diesel-trolley tracks and electric cars are determined based on technical-economic and ecologic feasibility.
A motor drive chassis has been developed for use in the Plutonium Protection System. Rotation of the desired carrousel in a secure storage module is controlled by this chassis which supplies the power and drive pulses required by the carrousel motor. This work was sponsored by the Department of Energy/Office of Safeguards and Security (DOE/OSS) as part of the overall Sandia Fixed Physical Protection Program.
The Na+-driven bacterial flagellar motor is a molecular machine powered by an electrochemical potential gradient of sodium ions across the cytoplasmic membrane. The marine bacterium Vibrio alginolyticus has a single polar flagellum that enables it to swim in liquid. The flagellar motor contains a basal body and a stator complexes, which are composed of several proteins. PomA, PomB, MotX, and MotY are thought to be essential components of the stator that are required to generate the torque of the rotation. Several mutations have been investigated to understand the characteristics and function of the ion channel in the stator and the mechanism of its assembly around the rotor to complete the motor. In this review, we summarize recent results of the Na+-driven motor in the polar flagellum of ...
Most chemical reactions in industry and biology are catalytic and play a role at some stage of the processing of about 80% of the goods manufactured in the U.S., yet catalysis is a neglected subject in chemical education. This book integrates the fragmentary treatment accorded the topic until now. It covers, in a unified way, catalysis in solutions, by enzymes, in synthetic polymers within the molecular scale cages of zeolites and other molecular sieves, and on surfaces of inorganic solids. The central ideas are chemical; and principles are illustrated by emphasizing industrial reactions and catalysts.
A compression ignition engine was operated on dual fuel principle inducting two commercial fuels and four pure hydrocarbon fuels in turn through intake manifold along with air and injecting diesel fuel to initiate the combustion in the conventional manner. The engine was operated at different loads and at each load the quantity of inducted fuel was increased gradually till knocking set in. The engine performance and exhaust pollutant emissions were recorded at different operating conditions. It was observed that the extent of induction and the effect on the performance depend on the properties of the inducted fuel such as volatility, self ignition temperature and oxidation characteristics. The energy release during the cycle was also observed to shift depending on the properties of inducted fuel. With the dual fuel operation, the thermal efficiency at part loads was observed to be ...
Purpose. The paper introduces a novel design of air-core inductive sensors in printed circuit board (PCB) technology for a tongue control system. The tongue control system provides a quadriplegic person with a keyboard and a joystick type of mouse for interaction with a computer or for control of an assistive device. Method. Activation of inductive sensors was performed with a cylindrical, soft ferromagnetic material (activation unit). Comparative analysis of inductive sensors in PCB technology with existing hand-made inductive sensors was performed with respect to inductance, resistance, and sensitivity to activation when the activation unit was placed in the center of the sensor. Optimisation of the activation unit was performed in a finite element model. Results. PCBs with air-core indu...
The role of phytochrome in the induction of nitrate reductase of etiolated field peas (Pisum arvense L.) was examined. Terminal bud nitrate concentration increased in darkness, and...Full Text Available
ObjectiveTo investigate the effect of maternal obesity on mode of delivery following induction of labour (IOL) for prolonged pregnancy and subsequent intrapartum and neonatal complications.DesignRetrospective...Full Text Available
AimThe goal of this study is to characterize the changes in 33 biomarkers within the gingival crevicular fluid during the 3-week induction and 4-week resolution of...Full Text Available
Based on a detailed analysis of the inter-relationship in the current, voltage, electromagnetic torque and ratio of the difference between the speed of rotor and the speed of rotary magnetic field to the later in the motor, the root cause was point out, which leads to the protection fuses' failure of the motor in the starting stage, which drives the turbine-generator set to rotate at low speed before its startup. Two solutions to avoid the situation are proposed, too. (authors)
An energy control strategy (10) for a hybrid electric vehicle that controls an electric motor during bleed and charge modes of operation. The control strategy (10) establishes (12) a value of the power level at which the battery is to be charged. The power level is used to calculate (14) the torque to be commanded to the electric motor. The strategy (10) of the present invention identifies a transition region (22) for the electric motor's operation that is bounded by upper and lower speed limits. According to the present invention, the desired torque is calculated by applying equations to the regions before, during and after the transition region (22), the equations being a function of the power level and the predetermined limits and boundaries.
A growing body of evidence in cognitive science and neuroscience points towards the existence of a deep interconnection between cognition, perception and action. According to this embodied perspective...Full Text Available
The OSP (Operating Safety Procedure) required for performance of electrical arc testing of CFC replacement fluids was renewed. Electrical breakdown tests at one atmosphere pressure have been performed for R-22, R-134a, and R-125/R-143a (50:50 blend; R-507), and breakdown products identified. No differences in HCFC breakdown products are seen in the presence or absence of lubricant oils. The design of the high pressure-high temperature test stand has been finalized, and construction initiated during this quarter. Three motor stators and rotors were received from Tecumseh Products Company for use in motor burnout tests. A test plan for the motor breakdown tests is in preparation.
... And those who study cognition select problems (eg, tower of Hanoi, missionaries and cannibals, logic theorems) with minimal perceptual and motor ...
Cerebral periventricular white matter injury stands as a leading cause of cognitive, behavioral and motor impairment in preterm infants. There is epidemiological and histopathological evidence...Full Text Available
Idiopathic achalasia is a primary esophageal motor disorder characterized by esophageal aperistalsis and abnormal lower esophageal sphincter (LES) relaxation in response to deglutition. It is a rare...Full Text Available
AIM: To investigate the effects of gallbladder stones on motor functions of the gallbladder and the dynamics of bile flow in asymptomatic gallstone disease.METHODS: Quantitative hepatobiliary...Full Text Available
BackgroundThe purpose of this research was to examine whether waterpipe smokers experience increased risk of motor vehicle crashes.MethodsIn a telephone...Full Text Available
...identified as oil when the shipment document accurately describes the material as: aviation fuel, diesel fuel, fuel oil, gasoline, jet fuel, kerosene, motor fuel, or...
Because power requirements in induction heating applications are largely dependent on the physical properties of the product to be heated, inducting, heating is mainly used in steelwork applications, for the manufacture of finished or semi-finished parts. Applications here cover five main types of steelworks operation: smelting, heating prior to forming, heat treatment, surface treatment, and assembly process. At the same time, technological progress has opened up innovative applications in sectors such as chemical and agro-food industries. Other emerging applications for induction include direct forming of liquid metal, wholly or partially replacing mechanical transformations on solid metal. Techniques include electromagnetic forming, continuous cold-crucible casting, electromagnetic mixing, flow control by continuous magnetic field, and production of intense sliding fields (pumps, flow regulation). (author)
An all solid-state kicker pulser for a proton radiography system has been designed. Multiple solid-state modulators stacked in an inductive-adder configuration are utilized in this kicker pulser design. Each modulator is comprised of multiple metal-oxide-semiconductor field-effect transistors (MOSFETs) which quickly switch the energy storage capacitors across a magnetic induction core. Metglas is used as the core material to minimize loss. Voltage from each modulator is inductively added by a voltage summing stalk. A circuit model of a prototype inductive adder kicker pulser modulator has been developed to predict the performance of the pulser modulator. The modeling results are compared with experimental data.
This paper reports on the superiority of zeolites over amorphous solids which is well documented for solid acid catalysts of industrial use. Crystalline supports, likewise, open attractive perspectives for catalysis by metals, alloys, and ligated metal clusters. Size and location of clusters can be controlled by careful design of the preparation conditions. Pore dimensions control the access of reactants to active sites and escape paths for products. Cage dimensions determine which transition states can be attained; window apertures are functional in isolating metal clusters from each other, thus preventing ther coalescence and growth. The ship-in-a-bottle method permits deisgn of fairly large active complexes entrapped in zeolite cages. Orientation of non-spherical molecules in a zeolite proe helps to direct their collision with a metal particle to the head on mode; however, isolated Pt atoms hidden in niches of the pore walls can attack ...
Audible noise from corona discharge had been identified as one of the most important factors in the design of conductor configurations for high-voltage transmission lines. 500 kV and above. Therefore this paper describes audible noise characteristics of 6 X 480 mm{sup 2} conductor bundle in KEPRI 765 kV Test Line and Corona Cage. Prediction formula for audible(corona) noise on a 765 kV Transmission Line was developed using this results. (author). 4 refs., 4 figs., 4 tabs.
Phytoplankton community was investigated in the cage culture area of Daya Bay during a diurnal cycle. Two rainfalls occurred during the course of the experiment and decreased the surface seawater salinity in the aquaculture area. A total of 38 species were identified, of which the dominant species included Pseudo-nitzschia spp. and Skeletonema costatum. Water stratification obstructed the vertical migration of dinoflagellates. Statistical analysis indicated that Synechococcus showed negative relationship with silicate and ammonia, which indicated that Synechococcus adapted to grow at oligotrophic environment. Phytoplankton community structure implied the risk of Pseudo-nitzschia spp. blooms in the aquaculture area of Daya Bay.
An analysis of the diagnosis of loading and service dependability of a rail-mounted excavator used in surface lignite mining is described. Wheel power vibrations in electric motor bearings and electric motor input bearings to the gearbox were measured in situ, in horizontal, vertical, and axial directions. The data were analyzed using a mathematical relationship. The results are presented in a loading diagram that shows the deterioration and the acceptable lower bound of machine conditions over time. Work is continuing. 5 refs., 1 fig.
The addition of 0.0005-0.5 weight% linoleic acid trimer to synthetic motor fuels composed of 95.0-99.8% technical-grade alcohol (EtOH or MeOH) and 0.2-5.0% water inhibits the corrosion induced by the impurities, such as aliphatic acids 0.5-10.0, aliphatic aldehydes 0.5-10.0, and aliphatic esters 0.5-10 mg/100 ml alcohol.
Motivated by recent experiments on KIF1A, a representative member of single-headed kinesin motor proteins family, we develop a theoretical model of intra-cellular transport by mutually interacting molecular motors. The model explicitly accounts not only for the hydrolysis of ATP, but also for the ratchet mechanism which is believed to drive each individual KIF1A motor. We study the model by a combination of analytical and numerical techniques. A remarkable feature of this model is that all the parameters in it can be completely evaluated from experimental data. Our results in the dilute limit are in excellent quantitative agreement with the empirical data from single molecule experiments. In the high density regime the predictions of the model also agree qualitatively with the corresponding experimental observations. We derive a phase diagram that shows the influence of hydrolysis and Langmuir kinetics on the collective ...
Magnetic properties of a recently developed Fe-based amorphous alloy with a high saturation induction of 1.65 T are reviewed. The increased saturation induction is fully utilized in transformers with reduced magnetic losses, physical sizes and audible noises, minimizing some of the drawbacks of amorphous metal-based transformers based on a currently available amorphous alloy. Impacts of this on the worldwide energy savings and reduction of greenhouse gas emissions are discussed. A recent effort in achieving a saturation induction beyond 1.65 T in nanocrystalline alloys is mentioned.
Tests have been conducted on a special compression ignition research engine to investigate the effects of gaseous fuels on the ignition delay in dual fuel engines. Diesel oil, n-heptane, or cetane were used as pilot fuels, and hydrogen, carbon monoxide, or methane were inducted in the intake manifold. Induction of nitrogen was used as a reference to eliminate the influence of changes in oxygen concentration and specific heats. Helium was inducted in additional tests. From the results of a number of parameter variations, the cylinder charge temperature (determined by intake temperature and compression ratio), the pilot fuel amount, and the flow of combustible gas were found to have the most significant influence on the ignition delay.
In response to stress, cells start transcriptional and transcription-independent programs that can lead to adaptation or death. Here, we show that multiple inducers of autophagy, including nutrient...Full Text Available
A device made of amorphous silicon which exhibits inductive properties at certain voltage biases and in certain frequency ranges in described. Devices of the type described can be made in integrated circuit form.
Apr 9, 2003 ... Adam Kissiah Jr., a retired KSC engineer, will be honored for his development of the digital hearing aid technology that led to the cochlear ...
... ge aircraft engines (geae) has taken to development an induction plasma deposition (ipd) processing method for the fabrication of ti6242/sic mmc ...
The effects of temperatures, durations of treatment, and derivations from spermatophores or spermaries on in vitro acrosome reaction of the spermatozoa in the Chinese mitten crab Eriocheir sinensis...Full Text Available
Synthesis of wild-type Neurospora crassa assimilatory nitrate reductase is induced in the presence of nitrate ions and repressed in the presence of ammonium ions. Effects of several...Full Text Available
This chapter consists of some points including an introduction, the basic parts of mass spectroscope device, sample introduction into the inductively coupled plasma, pneumatic nebuliser, ultrasonic nebuliser, dry gas cloud system, laser ablation unit, inductively coupled plasma-ion source, extraction of ions from ion source, mass analysis, quad-polar mass spectrometer, dual assembly mass spectrometer, mass spectrometer by calculation of time of flight, ion interferences and the ability of resolution, ion counter, working conditions of inductively coupled plasma mass spectroscope device, efficiency of ion transportation in an inductively coupled plasma mass spectroscope device and applications of analysis using mass spectroscope of induced plasma including nuclear, industrial, geological, environmental and archaeological applications, measurement of isotopes ratio and applications in tracing crimes.
Several scientists have proposed that DNA repair deficiencies and the induction of a mutator phenotype are responsible for the generation of multiple mutagenic alterations in cancer cells. I propose...Full Text Available
Synthesis of protein molecules in a cell are carried out by ribosomes. A ribosome can be regarded as a molecular motor which utilizes the input chemical energy to move on a messenger RNA (mRNA) track that also serves as a template for the polymerization of the corresponding protein. The forward movement, however, is characterized by an alternating sequence of translocation and pause. Using a quantitative model, which captures the mechanochemical cycle of an individual ribosome, we derive an {\\it exact} analytical expression for the distribution of its dwell times at the successive positions on the mRNA track. Inverse of the average dwell time satisfies a ``Michaelis-Menten-like'' equation and is consistent with the general formula for the average velocity of a molecular motor with an unbranched mechano-chemical cycle. Extending this formula appropriately, we also derive the exact force-velocity relation for a ribosome. Often many ribosomes ...
The purpose of this project was to build a long-range, parallel hybrid gas/electric vehicle capable of driving beyond the communter capabilities of series hybrid vehicles. It was envisioned that since the gas engine would be able to independently propel the car when needed and that the electric motor would be capable of doing the same, then you have a very desirable situation where this car can operate much more cheaply on electricity for the short distance runs under approximately 60 miles and also be able to propel the vehicle via the gas engine on the long-distance trips. During the time the car would be operating in the gas engine mode, it would be also recharging the 16 deep cycle batteries via the electric motor now being used as a generator. Then, even on long-distance trips, the electric motor could be used, after having been fully or partially recharged, to even further reduce cost per mile.
Several components of high-temperature reactor units have roller bearings in order to carry out their motions without much friction. The use of such bearings poses friction and wear problems which cannot be mastered by commercial roller bearing technology. Possible improvements of coating, cage design and bearing materials as well as of their parameters were registered and studied. The service life of dry lubricated bearings was considerably improved. With a radial or axial load on the bearing of {>=} 10% of the static load, {approx_equal} 20x10{sup 6} rolling motions/actuations can be performed. The connections between surface compression and wear were determined, and optimum conditions for the transfer of lubricants from the cage onto the bearing race were worked out. Coating of corrosion-resistant roller bearing steels with the HRB-M{sub 0}S{sub 2} running-in coating could be proved. New cage designs and materials ...
The experimental superconducting magnetic system of 0.5 MJ energy storage is described. The step variation of the winding inductance provides a control by the discharge current at the energy output on a high-ohmic load. The voltage on a load is 45 kV at the current 1100 A under the controllable discharge conditions. The energy transfer coefficient constitutes 0,76 under the maximum-to-minimal current ratio equal to 1.3. 7 refs., 3 figs., 2 tabs.
The effects of sodium ions on the uptake of Hg2+ and induction of the Tn21 mer operon were studied by using Escherichia coli HMS174 harboring the reporter plasmids pRB28 and pOS14. Plasmid pRB28 carries...Full Text Available
Ditercalinium, an antitumor bifunctional intercalator which forms a high affinity reversible complex with DNA, was found to be specifically cytotoxic for polA and lig7 E. coli strains. In the polA strain,...Full Text Available
A previous study described the basic theoretical expectations of the magnetic dipole radiation and unipolar induction of pulsars and presented observational results. This paper further discusses the difference between the two braking mechanisms and analyses the results of a statistical study through observed data of apparent beamwidth's distributions and a geometrical method. The theory of magnetic dipole radiation of pulsars agrees with the observations. Unipolar induction as a braking mechanism is not consistent with the observations.
Most standard accounts of human anatomy and physiology are designed to meet the requirements of medical education and therefore consider their subject matter from the standpoint of typical rather than...Full Text Available
Locomotion is a complex behavior affected by many different brain- and spinal cord systems, as well as by variations in the peripheral nervous system. Recently, we found increased gene expression for EphA4, a gene intricately involved in motor neuron development, between high-active parental strain C57BL/6J and the low-active chromosome substitution strain 1 (CSS1). CSS1 mice carry chromosome 1 from A/J mice in a C57BL/6J genetic background, allowing localization of quantitative trait loci (QTL) on chromosome 1. To find out whether differences in motor neuron anatomy, possibly related to the changes in EphA4 expression, are involved in the motor activity differences observed in these strains, motor performance in various behavioral paradigms and anatomical differences in the ventral roots ...
A patient is presented with a cervical spinal cord transection which occurred after a motor vehicle accident in which the air bag deployed and the seat belt was not in use. The patient had complete...Full Text Available
Deep brain stimulation of the subthalamic nucleus (STN-DBS) is efficacious in treating the motor symptoms of Parkinson’s disease (PD). However, the impact of STN-DBS on the progression...Full Text Available
Mar 1, 2011 ... Bending moments recorded by sensors on the aluminum tube. ... the escape rocket motor, tests also were made with the escape tower and rocket .... Incoming photographic data will be electronically converted and processed ...
Various energy sources and motors of divers types can be used in electric cars with operating modes subjected to a number of particular constraints. As a result, the possible structures of the converters, that are analysed in detail, are about a dozen in number. Also considered is the use of solid-state components - thyristors, power transistors and new components.
BackgroundAlthough some previous studies have suggested that posttraumatic growth (PTG) is comprised of several factors with different properties, few have examined both the association...Full Text Available
Four temperature sensors were provided instead of the previous two sensors. 4. ... Incoming signals from either one or two ground stations at a frequency of .... The propulsion subsystem consists of a single solid-propellant rocket motor. ...
The bulk alignment of actin filament sliding movement, powered by randomly oriented myosin molecules, has been observed and studied using an in vitro motility assay. The well established,...Full Text Available
BackgroundAmyotrophic lateral sclerosis (ALS), a common late-onset neurodegenerative disease, is associated with fronto-temporal dementia (FTD) in 3–10% of patients....Full Text Available
Calpains are Ca2+-dependent proteinases that mediate protein turnover in crustacean skeletal muscles. We used an antibody directed against lobster muscle-specific calpain (Ha-CalpM)...Full Text Available
Vocal learning is a critical behavioral substrate for spoken human language. It is a rare trait found in three distantly related groups of birds-songbirds, hummingbirds, and parrots. These avian groups...Full Text Available
Objective:Parkinson disease (PD) may affect the autonomic nervous system and may cause constipation; however, few studies have explored constipation preceding the motor onset of...Full Text Available
Mutations in SPTBN2, the gene encoding β-III spectrin, cause spinocerebellar ataxia type 5 in humans (SCA5), a neurodegenerative disorder resulting in loss of motor...Full Text Available
Blunt chest-wall trauma is common; however, resultant tricuspid valve rupture is rare and can be subtle in its presentation. Transthoracic echocardiography plays a key role in diagnosis.Herein,...Full Text Available
In the interests of fuel economy in motor vehicles, this article discusses the importance of waste heat recovery and then goes on the explore options such as hybrid electric cars, thermal engines with low loss platforms, pure electric vehicles and fuel cell vehicles. (UK)
Chemical genetics is an emerging approach to investigate the biology of host-pathogen interactions. We screened several inhibitors of ATP-dependent DNA motors and detected the gyrase B inhibitor coumermycin...Full Text Available
ObjectiveTo investigate the impact white matter hyperintensities (WMH) detected on MRI have on motor dysfunction and cognitive impairment in non-demented elderly...Full Text Available
The growing use of coal for heating and electric power generation and diesel engines in light duty motor vehicles will increase not only the existing atmospheric concentrations of criteria pollutants...Full Text Available
The effects of 2 forms of response interruption and redirection (RIRD)—motor RIRD and vocal RIRD—were examined with 4 boys with autism to evaluate further the effects of this intervention...Full Text Available
BackgroundOur motor actions normally generate sensory events, but how do we know which events were self generated and which have external causes? Here we use temporal adaptation...Full Text Available
It has previously been established that muscles become active in response to deviations from a threshold (referent) position of the body or its segments, and that intentional motor actions result from...Full Text Available
BackgroundBrains interact with the world through actions that are implemented by sensory and motor processes. A substantial part of these interactions consists in synchronized goal-directed...Full Text Available
The pharmacokinetic concepts of bioavailability and biotransformation are introduced into the assessment of public health risk from experimental data concerning the emissions of potentially mutagenic...Full Text Available
BackgroundPhysical performance measures are widely used to assess physical function, providing information about physiological and biomechanical aspects of motor performance. However...Full Text Available
Background: The objective of this study was to assess the factors associated with the traffic mortality in the region of Central Macedonia in order to produce evidence in building up preventive...Full Text Available
Essential in mitosis, the human Kinesin-5 protein is a target for >80 classes of allosteric compounds that bind to a surface-exposed site formed by the L5 loop. Not established is why there...Full Text Available
...1) A privately owned motor vehicle. (2) A privately owned boat. (3) An indigenous animal, military working dog, or guide dog for the blind or visually-impaired accompanying its owner. (4) A narcotic or dangerous drug or...
The infrared spectrum of the rotovibrational band {ital v}=0{r_arrow}2 of parahydrogen has been observed in the condensed phases down to {ital T}=2 K. In the solid, phonon and roton sidebands exhibit peaks corresponding to those observed in the fundamental. Contributions arising from the reorientation of ortho-H{sub 2} impurities have been detected. The {ital Q}{sub 1}(0)+{ital S}{sub 1}(0) band has been resolved into an asymmetric doublet, and the origin of this latter is discussed. In the liquid phase the observed line shapes include strong translational contributions, and are accounted for by assuming that at short times the excited molecule is encapsulated in the cage of nearest neighbors.
In recent years, cobia has become an emerging farmed species in Asia due to its quick growth and high economic value. This study collects biological and economic data affecting the economic performance of cobia farming in three countries, namely Taiwan, China, and Vietnam. The data are collected by questionnaire sampling and analyzed by multivariate statistical analysis in order to compare the key factors affecting the production and economy of cobia farming in these three countries. The results show that Taiwan, China, and Vietnam have significant differences in input intensities and profitability. China has the highest input intensity (3372.42?TWD/m3), as its high stocking density increases feed input. Taiwan has the highest unit input cost (103.44?TWD/kg), as the high quality of the pro...
A 206-size hybrid (ceramic/steel) cylindrical roller bearing was tested in MIL-L-23699 C oil at several speeds and loads. Heat-generation data was collected and subsequently correlated with bearing-analysis software. Bearing-cage slip data was also collected at various oil-flow rates, oil temperatures, and with both MIL-L-7808 J and MIL-L-23699 C oils. The hybrid bearing was tested in MIL-L-23699 C oil for for 25 hours at 2220 N radial load and 1.08 MDN shaft speed. The hybrid bearing technology demonstrated in the report is applicable to the Integrated High Performance Turbine Engine Technology Initiative. 15 refs.
Anthracene-bis-resorcinol is an interesting molecule as it forms a hydrogen-bonded network when guest molecules with weak polarity are included. Focused ion beam (FIB) was irradiated on a part of its amorphous film with low dose, and the film was exposed to the vapor of guest molecules. From fluorescence and AFM analyses of this film, it was found that no inclusion compound was formed in FIB irradiated area, i.e. FIB irradiation suppresses the ability to form the inclusion compounds. By utilizing this phenomenon, we succeeded in a microfabrication of relief structures consisting of inclusion compounds which has different fluorescence from its surrounding. Morphology, fluorescence, and IR absorption analyses indicated that hydroxyl or resorcin groups are damaged by ion beams, and consequently a formation of hydrogen-bonded networks, which play a role of a lattice caging guest molecules, becomes impossible.
A series of [60]fullerene-substituted phenylalanine (Baa) and lysine derivatives have been prepared by the condensation of 1,2-(4prime-oxocyclohexano)fullerene with the appropriately protected (4-amino)phenylalanine and lysine, respectively. Conversion of the imine to the corresponding amine is achieved by di-acid catalyzed hydroboration. The reduction of the imine is not accompanied by hydroboration of the fullerene cage. The [70]fullerene phenylalanine derivative has also been prepared as have the di-amino acid derivatives. The compounds were characterized by MALDI-TOF mass spectrometry, UV/Vis spectroscopy, and cyclic voltammetry. 1H and 13C NMR spectroscopy allowed the observation of diastereomers. Fullerene-substituted peptides may be synthesized on relatively large scale by solid-pha...
The reduced polluting emissions make natural gas a quite interesting alternative fuel for automotive applications. Therefore a car diesel engine has been transformed into a dual fuel engine with pilot injection via the common rail injection system used to ignite the methane-air charge. Standard injection pumps show a certain instability at low flow rates and high engine speed. On the opposite the new common rail system allows to ignite the fuel in all conditions with an amount of gas oil less than 8% of the entire energy required by the engine was enough to ignite the fuel. Furthermore, a power increase has been obtained, with an overall efficiency equal to or even higher than a conventional engine. The article deals with a series of test carried out on 1929 cm{sup 3} direct injection turbo-charged engine and presents the preliminary results. [Italian] La riduzione delle emissioni inquinanti rende il metano un combustibile alternativo piuttosto interessante per applicazioni ...
Technologic regimes of cryomotor rotor fabrication are determined. Blanks of yttrium ceramics powder are molded hydrostatically at 400-600 MPa. To confirm the serviceability of electric machines of the considered, a hysteretic 10 W power electric motor with the following dimensions of HTSC-ceramics rotor: external diameter - 56 mm; internal diameter - 45 mm, height - 60 mm, is developed and tested in the liquid nitrogen medium. 8 refs.; 8 figs.; 1 tab.
The magnetorheological suspension (MRS) brake is of the monoblock type. The main part of the electromagnetic brake is an electromagnet, between whose poles two MRS disks are placed. For distances between disks of 0.65x10"-"3 m#+-#10%, revolutions of the electric motor, coupled to the electromagnetic brake, ranging between 200 and 1600 rev/min and braking powers of up to 85 W, there are no differences in revolutions between the disks of the electromagnetic brake. For fixed revolutions of the electric motor, the revolution of the parallel disk can be modified continuously by means of the intensity of the magnetic field. In all cases, the quantity of MRS is of 0.35x10"-"3 kg.
This invention relates to liquid hydrocarbon motor fuels improved by the addition of an azido compound. Specifically, the azido compounds of the present invention have the following general formulas N/sub 3/-R/sub 2/, N/sub 3/-R/sub 2/-N/sub 3/, N/sub 3/-R/sub 3/-O-R/sub 4/-N/sub 3/, N/sub 3/-R/sub 3/-CO/sub 2/-R/sub 4/-N/sub 3/.
In a positive polarity induction adder each of the induction cavities is a cathode, which emits electrons at a unique potential. These broad spectrum electrons strongly affect Magnetically Insulated Transmission Line (MITL) behavior. Electron flow decreases the cavity-to-MITL coupling efficiency, and reduces the power transport efficiency along the system. Also, the operating impedance of the MITL is lowered, reducing the diode impedance required for good coupling and good total system power efficiency. It is therefore imperative to understand the details of MITL electron flow. In previous work, measurement of MITL electron flow for a twenty-stage linear induction adder (Hermes III), operated in positive polarity, was compared with simulations. There was qualitative agreement, but some differences were noted. For example, measured electron flow in the first cavities was greater than in the simulations. The authors have ...
Objective: To discuss the clinical application value of dual energy subtraction (DES) in direct digital radiography of chest. Methods: 83 cases of chest digital radiography(DR) using double-energy subtraction (DES) were randomly selected, and three posterior-anterior (PA) chest films (standard image, bone image and soft tissue image) were obtained in each case, which is so called 'bone and soft tissue separated' technology. Results: With the aid of double energy subtraction (DES), the bony chest was subtracted, the sensitivity and specificity of pulmonary calcification were improved, and sensitivity of pulmonary nodes was also improved, enhancing the distinction between pulmonary benign or malignant lesions, enlightening the diagnosis of chest cage lesions, and showing a clear superiority in the detection of pulmonary nodes comparing to common chest films. The double energy subtraction (DES) films showed a higher diagnostic accuracy in the detection of bony ...
The eastern oyster (Crassostrea virginica) developed neoplastic disorders when experimentally exposed both in the laboratory and field to chemically contaminated sediment from Black Rock Harbor (BRH), Bridgeport, Connecticut. Neoplasia was observed in oysters after 30 or 60 days of continuous exposure in a laboratory flow-through system to a 20 mg/L suspension of BRH sediment plus postexposure periods of 3, 30, or 60 days. Composite tumor incidence was 13.6% for both exposures. Tumor occurrence was highest in the renal excretory epithelium, followed in order by gill, gonad, gastrointestinal, heart, and embryonic neural tissue. Regression of experimental neoplasia was not observed when the stimulus was discontinued. In field experiments, gill neoplasms developed in oysters, deployed in cages for 30 days at BRH and 36 days at a BRH dredge material disposal area in Central Long Island Sound, and kidney and gastrointestinal neoplasms developed in ...
Investigations of radionuclide metabolism and effects in various mammalian species revealed important similarities between animals and humans and between some animal species. These include skeletal deposition of radium and radiostrontium in bone volume; deposition on bone surfaces of plutonium and other actinides; liver deposition of actinides; induction of skeletal or liver malignancies by these radionuclides; induction of tooth and jaw abnormalities; mammary cancer induction by radium in humans and in the beagle; depression of circulating cells in blood; and induction of bone fractures. There are also inter-species differences that may not have been noted if multiple species (including humans) had not been studied. Some of these are more rapid excretion of radium in humans compared with most other mammals; induction by radium of eye melanomas in animals but not humans; rapid loss ...
Objective: To find out safety and efficiency of Misoprostol in cervical ripening and induction of labour to achieve vaginal delivery. Results: From Misoprostol insertion to delivery time was 4-24 hours. Vaginal delivery was achieved in 80.2%, which included spontaneous, forceps and vacuum extraction. Caesarean section rate was 19.7%. Indications for C. Section included Misoprostol unresponsiveness 11% and fetal distress in 8.6%. Oxytocin augmentation was required in 32% of cases. Term babies were 58%. Intrauterine death and neonatal deaths were 9.8% and 8.6% respectively. Hyper stimulation and postpartum haemorrhage was seen in 2.4% and 3.7% of patients respectively. Conclusion: intravaginal Misoprostol is well tolerated and is very effective for the induction of labour in eclampsia. It helps vaginal delivery in toxemic patients, reduces maternal morbidity, mortality and hospital stay. (author)
To test the hypothesis that leaf level photosynthetic related traits might confer late successionals a competitive advantage over early successionals in low light growth conditions, steady photosynthetic assimilation and dynamic photosynthetic induction related traits were examined in low light grown seedlings with contrasting successional status. Compared with the early successionals, late successionals as a group significantly exhibited lower leaf gas exchange rates. While late successionals required a longer time to respond to simulated sunflecks, they had lower rates of induction losses after sunflecks. Such photosynthetic induction traits allowed late successionals to more effectively utilize subsequent sunflecks. It was observed that plants with lower gas exchange rates responded mor...
The high repetition rate and low single-pass gain inherent in an rf-driven Free Electron Laser (FEL) dictate that the laser system be configured as an oscillator. This allows the laser's electric field to build up over many passes around a high Q cavity. By way of contrast, the high-current capability of the Induction Linac (IL) system permits high single-pass optical gain, but the relatively low duty factor precludes oscillator operation; the pulses are neither long enough nor often enough to permit a field to accumulate in a cavity. The IL is thus configured as a MOPA (master oscillator/power amplifier) with a conventional laser serving as the MO. This report concentrates on the status of IL-driven FEL research at LLNL and gives a description of several applications for the high-peak-power radiation produced by an induction linac FEL.
The enzyme TEM1-b-lactamase has been used as a model to study the impact of different cultivation and induction regimes on the structure of cytosolic inclusion bodies (IBs). The protein has been heterologously expressed in Escherichia coli in fed-batch cultivations at different temperatures (30, 37, and 40degreeC) as well as induction regimes that guaranteed distinct product formation rates and ratios of soluble to aggregated protein. Additionally, shake flask cultivations at 20, 30, and 37degreeC were performed. IBs were sampled during the whole bioprocess and structural analysis was performed by attenuated total reflectance Fourier transform infrared (ATR-FT-IR) spectroscopy. This work clearly demonstrates that the tested production regimes and rates had no impact on the IB structure, wh...
Several lines of evidence are presented that indicate that the level of tetracycline resistance of Esherichia coli strains harboring plasmid pBR322 varies according to whether the SOS system of the host bacteria has been induced. These include use of strains in which the SOS system is expressed constitutively (lexA def.), is thermoinducible (recA441) or noninducible (lexA ind-), or is highly repressed (multiple copies of lexA+). Similar induction was observed with the product of another plasmid gene, beta-lactamase. The amounts of extractable plasmid DNA were also increased by SOS induction, and we propose that the SOS-induced increases in levels of tetracycline resistance and beta-lactamase activity are due to an increased plasmid copy number.
Mini-LIA is a miniature of a linear induction accelerator developed by China Academy of Engineering Physics and Tsinghua University in 2007. It has been constructed with a thermionic cathode in an electron injector and a metglas core in the induction accelerator cavities. A double-pulsed electron beam was produced for the first time in China on the Mini-LIA with a thermionic cathode in the electron gun and a metglas core in the induction accelerator cavities. A double-pulsed beam current of more than 1.1A was obtained on condition of 80 kV double-pulsed high voltage produced by pulsed power system supplying to the injector and accelerating modules. Some primary experiments for measuring the parameters of Mini-LIA has been performed, and some beam characterizations of Mini-LIA are presented. Further improvement is underway. (authors)
The first part of this article in two parts deals with the cupola furnace process regarding the energy consumption figures and efficiencies. The splitting of heat transfer into the two stages of melting and superheating makes the poor use of energy in superheating clear. For this reason the previously published idea of duplication, i.e. melting in a cupola furnace and superheating in an induction channel furnace or coreless induction furnace, has gained in interest. The last section of part I examines and compares cupola and electrode furnaces regarding the use of primary energy, where, surprisingly, roughly equal efficiencies of 20 to 25% are found for the melting processes considered.
Recent advances made in the area of amorphous and nanocrystalline alloys exhibiting high saturation inductions are reviewed. A new chemical composition was identified that achieves a saturation induction of 1.64 T in an iron-based amorphous alloy. This alloy, when used in electrical transformers, shows a much improved performance over the existing amorphous alloy. Nanocrystalline FeCoCuNbSiB alloys are found to have saturation induction levels reaching 1.7 T. These materials are suited for use in sensors and inductors carrying large currents. Some of these nanocrystalline alloys show a BH squareness ratio exceeding 90%, which can be utilized in pulse power devices. Recent developments in the applications of these materials are also pointed out.
We have investigated the transport of tritiated indole-3-acetic acid (IAA) in intact, red light-grown maize (Zea mays) coleoptiles during gravitropic induction and the subsequent development...Full Text Available
When faced with a harsh climate or inadequate food, some mammals enter a state of suspended animation known as torpor. A major goal of torpor research is to determine mechanisms that integrate...Full Text Available
The present invention relates to a method of recycling polymeric waste products into monomers and high value forms of carbon by pyrolytic conversion using an induction coupled RF plasma heated reactor.
Recommended treatment of chronic hepatitis B with interferon-α and/or nucleos(t)ide analogues does not lead to a satisfactory result. Induction of HBV-specific T cells by therapeutic...Full Text Available
BackgroundIn Pseudomonas fluorescens ST, the promoter of the styrene catabolic operon, PstyA, is induced by styrene and is subject to catabolite...Full Text Available
We have developed a method to extract and separate phytochelatins (PCs)—metal(loid) complexes using parallel metal(loid)-specific (inductively coupled plasma-mass spectrometry) and organic-specific...Full Text Available
BackgroundActivation of the signal transducer and activator of transcription 3 (STAT3) within antigen presenting cells (APCs) is linked to abnormal APCs differentiation and function....Full Text Available
Purpose: This paper reviews and reassesses the internationally accepted niches or ‘targets’ in bone marrow that are sensitive to the induction of leukaemia and primary...Full Text Available
A DNA sequence encoding the A chain of ricin toxin (RTA) from the castor bean plant, Ricinus communis, was placed under GAL1 promoter control and transformed into Saccharomyces cerevisiae. Induction...Full Text Available
A regulatory locus on the Staphylococcus aureus chromosome, designated sar, is involved in the expression of cell wall proteins, some of which are potentially important in the pathogenesis of endocarditis....Full Text Available
Rhizosphere acidification by Fe-deficient bean (Phaseolus vulgaris L.) plants was induced by trace amounts of divalent metal ions (Zn, Mn). The induction of this Fe-efficiency reaction...Full Text Available
Lifetime exposure to physical activity is an important construct for evaluating associations between physical activity and disease outcomes, given the long induction periods in many chronic diseases....Full Text Available
Carbenoxolone (CBX) is a semisynthetic derivative of the licorice root substance glycyrrhizinic acid and has been previously reported to induce only heat shock protein 70 [Hsp70, HSPA1A (the systematic...Full Text Available
Recovery of hydraulic conductivity after the induction of embolisms was studied in woody stems of laurel (Laurus nobilis). Previous experiments confirming the recovery of hydraulic...Full Text Available
Technologies for materials, processes, and manufacturing that will provide safe, .... advanced energy conversion techniques, and pulsed inductive and ... duration antimatter storage and transportation, and methods for utilizing ...... EVA systems can be found in the EVA Technology Roadmap of the EVA Project Plan. ...
A Monascus pilosus strain was selected for production of intracellular α-galactosidase. Optimum conditions for mycelial growth and enzyme induction were determined. Galactose...Full Text Available
Platelet-derived growth factor (PDGF) is a potent moderator of soft tissue repair through induction of the inflammatory phase of repair and subsequent enhanced collagen deposition. We examined the effect...Full Text Available
Effects of physical environment on plasma membrane semipermeability and osmotic induction of changes in aqueous cytoplasmic volume were studied in vegetative and spore cells of a plant pathogenic fungus,...Full Text Available
The author derives to which of the three types an irreducible UA representation which is obtained with the procedure of generalised induction belongs. The question whether or not the irreducible induced UA representations are on standardform is analysed. The results hold as well for induced PUA representations. (Auth.).
Importance of the fieldThe cytochrome P450 (CYP) isoforms that are selectively induced following exposure to structurally-diverse chemicals often are the ones capable...Full Text Available
Increased oxidative stress is associated with perinatal asphyxia and respiratory distress in the newborn period. Induction of nuclear factor erythroid 2 p45-related factor (Nrf2) has been shown to decrease...Full Text Available
The effect of different nitrogen compounds on the induction of reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase was examined in Neurospora crassa. Whereas in the wild-type strain...Full Text Available
Transcriptional regulation of the galactose-metabolizing genes in Saccharomyces cerevisiae depends on three core proteins: Gal4p, the transcriptional activator that binds to upstream activating DNA sequences (UASGAL); Gal80p, a repressor that binds to the carboxyl terminus of Gal4p and inhibits transcription; and Gal3p, a cytoplasmic transducer that, upon binding galactose and adenosine 5'-triphosphate, relieves Gal80p repression. The current model of induction relies on Gal3p sequestering Gal80p in the cytoplasm. However, the rapid induction of this system implies that there is a missing factor. Our structure of Gal80p in complex with a peptide from the carboxyl-terminal activation domain of Gal4p reveals the existence of a dinucleotide that mediates the interaction between the two. Biochemical and in vivo experiments suggests that nicotinamide adenine dinucleotide phosphate (NADP) plays a key role in the initial ...
Human skin is a local source of corticotropin-releasing hormone (CRH) and expresses CRH and CRH receptors (CRH-R) at mRNA and protein levels. Epidermal melanocytes respond to CRH by induction...Full Text Available
AbstractIntrathymic expression of tissue-restricted antigens (TRAs) has been viewed as the key element in the induction of central tolerance and recently, a central role for the autoimmune...Full Text Available
The use of infectious pathogens has allowed the detection of the development of synergism between pathogens and ubiquitous environmental chemical contaminants. This synergism has been demonstrated to...Full Text Available
In Experiment I, lever pressing by squirrel monkeys was maintained under a sequence of variable-interval, multiple variable-interval variable-interval, and multiple variable-interval extinction schedules...Full Text Available
Somatic radiation doses are recognized to be possible factors of carcinogenesis. In correctly performed mammography, however, even as screening test, the radiation dose does not reach such an order of magnitude that the benefit of the procedure as to prevention of breast cancer is called into question.
Previous experimental data from various laboratories indicate that endotoxin of gram-negative oral microorganisms might be one of the most important bacterial products involved in bone resorption during...Full Text Available
Water samples from several ponds in Minnesota were evaluated for their capacity to induce malformations in embryos of Xenopus laevis. The FETAX assay was used to assess the occurrence of malformations...Full Text Available
During the treatment of neonatal apnea, formula-fed infants, compared to breastfed infants, show nearly three-fold increase in clearance of caffeine, a substrate...Full Text Available
Experiments were conducted to determine the dose response of rat bladder urothelium to a range of different single and fractionated intravesicular doses of the carcinogen, N-methyl-N-nitrosourea (MNU)....Full Text Available
Unless relaxation of the stringent response is achieved, all nongrowing bacteria rapidly develop resistance to autolysis induced by a variety of agents, including all classes of cell wall synthesis...Full Text Available
TCDD and other polyhalogenated aromatic hydrocarbon ligands of the aryl hydrocarbon receptor (AHR) have been classically considered as non-genotoxic compounds because they fail to be directly mutagenic...Full Text Available
Colonization of barley (Hordeum vulgare cv Salome) roots by an arbuscular mycorrhizal fungus, Glomus intraradices Schenck & Smith, leads to elevated levels...Full Text Available
The effects of an electric current on ethylene biosynthesis were investigated in cucumber (Cucumis sativus L.) fruit that were producing almost no ethylene. Direct currents at 0.5...Full Text Available
The use of Bacillus thuringiensis (Bt) endotoxins to control insect vectors of human diseases and agricultural pests is threatened by the possible evolution of resistance in major pest...Full Text Available
The induction of voltages on pipelines and railroad signal wires can be a problem when high-voltage transmission lines share the right of way. A handbook and two computer programs provide the analytic tools for utilities to avoid the problem.
The reactive airways dysfunction syndrome (RADS), the reactive upper airways dysfunction syndrome (RUDS), the sick building syndrome (SBS), and the multiple chemical sensitivity syndrome (MCS) are overlapping...Full Text Available
Electric cars can be recharged via charging stations, battery exchange, or induction cable lanes in asphalted roads. The users' wishes remain unexplored, so a number of technologies are competing in this sector.
A linear induction accelerator that produces a beam of energetic heavy ions (T -- 10 GeV, A -- 200 amu) is a prime candidate as a driver for an inertial fusion power plant. Some early perceptions were that heavy-ion drive fusion would not be cost-competitive with other power sources because of the high cost of the accelerators. However, improved understanding of the physics of heavy-ion transport and acceleration (supported by experimental results), combined with advances in accelerator technology, have resulted in accelerator design costs -- 50% of previous estimates. As a result, heavy-ion drive fusion power plants are now projected to be cost-competitive with other conceptual fusion power plants. A brief formulation of transport and acceleration physics is presented here, along with a description of the induction Linac cost optimization code LIACEP. Cost trends are presented and discussed, along with specific cost estimates for several ...
A linear induction accelerator that produces a beam of energetic heavy ions (T #approx =# 10 GeV, A #approx =# 200 am#mu#) is a prime candidate as a driver for an inertial fusion power plant. Some early perceptions were that heavy-ion driven fusion would not be cost-competitive with other power sources because of the high cost of the accelerators. However, improved understanding of the physics of heavy-ion transport and acceleration (supported by experimental results), combined with advances in accelerator technology, have resulted in accelerator design costs -- 50% of previous estimates. As a result, heavy-ion driven fusion power plants conceptual fusion power plants. A brief formulation of transport and acceleration physics is presented here, along with a description of the induction Linac cost optimization code LIACEP. Cost trends are presented and discussed, along with specific cost estimates for several accelerator designs matched to ...
The alternative sigma factor ςB of Bacillus subtilis is required for the induction of approximately 100 genes after the imposition of a whole range of stresses and...Full Text Available
Metabolic profiling analyses were performed to determine metabolite temporal dynamics associated with the induction of acquired thermotolerance in response to heat shock and acquired freezing tolerance...Full Text Available
BackgroundEscherichia coli strain EL350 contains chromosomally integrated phage lambda Red recombinase genes enabling this strain to be used for modifying the sequence...Full Text Available
Retinoic acid inducible gene I (RIG-I) is a pattern recognition receptor (PRR) responsible for detection of nucleic acids from pathogens in the cytoplasm of infected cells and induction of type I interferon...Full Text Available
Spontaneous mouse models of cancer show promise to more accurately recapitulate human disease and predict clinical efficacy. Transgenic mice or viral vectors have been required to generate spontaneous...Full Text Available
BACKGROUND: H2-histamine receptors mediate a wide range of physiological functions extending from stimulation of gastric acid secretion to induction of human promyelocyte differentiation. We have previously...Full Text Available
The cellular properties of long-term potentiation (LTP) following pairing of pre- and postsynaptic activity were examined at a known glutamatergic synapse in the leech, specifically between the pressure...Full Text Available
We introduce cyclophosphamide-induced alopecia (CYP-IA) in C57BL-6 mice as a clinically relevant model for studying the biology of chemotherapy-induced alopecia and for developing anti-alopecia drugs....Full Text Available
Autophagy is an evolutionarily conserved degradative pathway that has been implicated in a number of physiological events important for human health. This process was originally identified as a response...Full Text Available
The in planta induction of anaerobic nitrate respiration by Erwinia carotovora subsp. atroseptica in relation to the in situ oxygen status in soft rotting potato tubers...Full Text Available
BackgroundBacterial constituents, such as Gram-negative derived lipopolysaccharide (LPS), can initiate inflammatory bone loss through induction of host-derived inflammatory...Full Text Available
BackgroundThe first week of human pre-embryo development is characterized by the induction of totipotency and then pluripotency. The understanding of this delicate process will have...Full Text Available
There is increasing concern for the potential adverse health effects of human exposures to chemical mixtures. To better understand the complex interactions of chemicals within a mixture, it is essential...Full Text Available
Charged particle beams in circular accelerators couple with their surroundings through induced electromagnetic fields. This interaction can be described by so-called coupling impedances. In the frequency domain the impedance in connection with the bunch spectrum allows for stability analysis and estimates. However, for simulation codes one usually needs the wakefunction, the equivalent of the impedance in time domain. Recently the transverse impedance of a cylindrical pipe with arbitrary surface impedance was given by L. Vos. An expression for the wakefunction of this transverse resistive wall impedance with inductive bypass is derived here.
Rotary furnaces are a well established alternative to cupola furnaces. Recent innovations in oxygas furnaces have made them the preferred choice even over medium-frequency electric furnaces in many European foundries. The article explains in what respects the rotary furnace is a new iron smelting concept, as different from the cupola furnace as the medium-frequency electric furnace. (author)
A study was conducted on diesel engines to find out the effect of induction rate of biogas on engine performance indices. The results of dual fuel engine performance was compared with diesel mode for various levels of biogas induction rate (0.3 to 7.2 l/s) engine load (20% to full load) and injection timing (20.6 to 48 before top dead centre). At full and 80% brake load, the best energy mix between diesel and biogas was 1.5:1 and 4:1 respectively. (author). 7 refs., 7 figs., 4 tabs.
Correct prediction of the fission products inventory in irradiated nuclear fuels is essential for accurate estimation of fuel burnup, establishing proper requirements for spent fuel transportation and storage, materials accountability and nuclear forensics. Such prediction is impossible without accurate knowledge of neutron induced fission yields. The uncertainty of the fission yields reported in the ENDF/B-VII.0 library is not uniform across all of the data and much of the improvement is desired for certain fissioning isotopes and fission products. We discuss our measurements of cumulative fission yields in nuclear fuels irradiated in thermal and fast reactor spectra using Inductively Coupled Plasma Mass Spectrometry. (author)
Correct prediction of the fission products inventory in irradiated nuclear fuels is essential for accurate estimation of fuel burnup, establishing proper requirements for spent fuel transportation and storage, materials accountability and nuclear forensics. Such prediction is impossible without accurate knowledge of neutron induced fission yields. The uncertainty of the fission yields reported in the ENDF/B-VII.0 library is not uniform across all of the data and much of the improvement is desired for certain fissioning isotopes and fission products. We discuss our measurements of cumulative fission yields in nuclear fuels irradiated in thermal and fast reactor spectra using Inductively Coupled Plasma Mass Spectrometry.
Results obtained on induced current and voltage caused by a high voltage transmission lines running parallel at a trolley bus contact lines, are presented. A computer program in Basic language, was developed to calculate the electric induction, problems of safety, a theoretical development and mathematical model of the electric factors between two lines (inductor and induced) are also discussed. 11 figs., 1 tab., 8 refs.
The rate of hepatic cytochrome P450 Cypla1 and Cyp1a2 induction was investigated in C57BL male mice during induction with o-aminoazotoluene (OAT), benzo[a]pyrene (BP) and 1,4-dihydroxyanthraquinone (AQ). The Cypla1 mPNA level determined by quantitative RT-competitive PCR increased more than three orders of magnitude during induction with OAT and BP compared with untreated animals and remained unchanged during induction with AQ. The Cypla2 mRNA level was only 8.5, 18.7 and 1.9 times higher during induction with OAT, BP and AQ respectively than in untreated mice. At the same time 7-Ethoxyresorufin-O-deethylase (EROD) and 7-Methoxyresorufin-O-demethylase (MROD) activities of Cypla were also investigated in liver. The increase of Cypla1 mRNA level correlated with the increase of EROD activity. This suggests involvement of the transcriptional mechanism of the inducibility of this enzyme. ...
The main problems with the use of neat vegetable oils in diesel engines are higher smoke levels and lower thermal efficiency as compared to diesel. The problem can be tackled by inducting a gaseous fuel in the intake manifold along with air. In this investigation, hydrogen is used as the inducted fuel and rubber seed oil (RSO), rubber seed oil methyl ester (RSOME) and diesel are used as main fuels in a dual fuel engine. A single cylinder diesel engine with rated output of 4.4 kW at 1500 rpm was converted to operate in the dual fuel mode. Dual fuel operation of varying hydrogen quantity with RSO and RSOME results in higher brake thermal efficiency and significant reduction in smoke levels at high outputs. The maximum brake thermal efficiency is 28.12%, 29.26% and 31.62% with RSO, RSOME and diesel at hydrogen energy share of 8.39%, 8.73% and 10.1%, respectively. Smoke is reduced from 5.5 to 3.5 BSU with RSOME and for RSO it is from 6.1 to 3.8 BSU ...
The latest inclined mine winder started operation in April, 1995 at the Kushiro Mining Station of Taiheiyo Coal Mining Co. A permanent magnet synchronous motor, a cycloconverter, and H{sub {infinity}} control are employed to complete the latest inclined mine winder. The winder is the world`s longest and fastest inclined mine winder, and the torque of the permanent magnet synchronous motor is the largest in the world. A report is made on the driving system placing emphasis on the points considered in the design. The gallery has the length of world`s longest 6,626m and the average gentle inclination of 6 degree. The worker transport car runs at the world`s fastest speed of 420m/min from the mouth to the bottom of the pit, making a round trip in 40 minutes. Speed is adjusted smoothly by the cycloconverter, and the car arrives at the destination safely in a short time due H{sub {infinity}} controlling. By the application of H{sub {infinity}} ...
Two headed motor proteins, such as kinesin and dynein, hidrolyze environmental ATP in order to propel unidirectionally along cytoskeletal filaments such as microtubules. In the case of kinesin, protein heads bind primarily on the alpha tubulin site of asymmetric alpha-beta 8nm-long tubulin dimers that constitute the microtubular protofilaments. Kinesin dimers overcome local binding forces up to 5pN and are known to move on protofilaments with ATP concentration-dependent speeds while hydrolizing on average one ATP molecule per 8nm step. The salient features of protein trajectories are the distinct abrupt usually 8nm-long steps from one tubulin dimer to the next interlaced with long quiescent binding periods at a tubulin site. Discrete walks of this type are characterized by substantially reduced variances compared to pure biased random walks, and as a result rule out flashing-type ratchet models as possible mechanisms for motor movement. On the ...
The objective of the program is to develop a domestic cooktop with low-NOx emissions and high efficiency. During the first two phases of the program, three design concepts were developed, and two versions of developmental prototypes using the IR-Jet approach were fabricated and tested. The third phase was initiated to address the design issues of burner turndown and modulation and to conduct the field test of a prototype with one IR-Jet and three conventional burners. Two prototypes containing one IR-Jet and three conventional burners and utilizing blower speed control for air/gas modulation were fabricated. One unit employed a brushless dc motor and the other a 2-pole ac motor. The ac motor prototype was field tested. Field testing showed the need for a mechanical air/gas valve for modulation and for a 1500 Btu/hr simmer setting. A 4-inch-diameter stepped-tile configuration provided input rates from 1500 to 8000 Btu/hr. A ...
Results related to the experimental measurement campaign to characterize atmospheric aerosol carried out near Avigliana (Turin) from 18 to 22 October 1994 are presented in this paper. In the frame of the project aimed at evaluating the impact of the mountain motor way A-32 Rivoli-Bardonecchia-Frejus on the Susa Valley environment and on man the present measurement campaign is the second, and last, one envisaged in the project. The sampling place is in the initial part of the Susa Valley while previous measurements were carried out in the high part of it. Mass mean concentrations result greater in the low than in the high part of the valley approximately by a factor of 3. It is not possible to prove a difference between the 3 sampling positions transversely placed from 20 to 80 m. in comparison with the motor way axis. Whereas mass mean concentrations dropped substantially due to atmospheric precipitations during the last two measurement day. ...
The spectrum of training aids used in the nuclear industry runs the gamut from the very basic (i.e., valve training aids - gate, globe, check) to the highly complex (i.e., nuclear full scope simulator). Designing and purchasing the best training aids take much time, detailed investigation, and good understanding of plant operations. The training aid that has given the New York Power Authority the best results has been the motor operator valve (MOV) trainer. Some of the items that make the MOV trainer a good choice are: (1) large number of MOVs in the plant, (2) importance of MOVs to safe plant operation, (3) detailed MOV procedures used by the plant, (4) history of MOV problems, and (5) ability to demonstrate important concepts and operation - hammer blow effect, torque and limit switch adjustment and functions, and actual sequence of operation of the limitorque valve operator.
An expert system was developed which helps maintenance personnel diagnose the condition of rotor and stator windings and their cores, in motors and generators rated 2300 V and above. The expert system, called MICAA[TM], used an approach which has been found to be effective for diagnosing medical problems. The program required the user to input machine nameplate information, operating status, and any past test data available. In addition, the program would suggest tests that may be useful, as well as provide guidance to maintenance personnel on what to look for in visual inspections of the machine. The expert system stored and correlated all this information, calculated the overall condition of the component in question, and identified the most likely specific causes of any deterioration. The basic methodology of motor and generator condition assessment, and the architecture and processing performed by MICAA to obtain these capabilities were ...
This manual is intended to serve several purposes. The first goal is to describe the capabilities and operation of the SMC processor package from an operator or user point of view. Secondly, the manual will describe in some detail the basic hardware elements and how they can be used effectively to implement a step motor control system. Practical information on the use, installation and checkout of the hardware set is presented in the following sections along with programming suggestions. Available related system software is described in this manual for reference and as an aid in understanding the system architecture. Section two presents an overview and operations manual of the SMC processor describing its composition and functional capabilities. Section three contains hardware descriptions in some detail for the LLL-designed hardware used in the SMC processor. Basic theory of operation and important features are explained.
The petroleum ether fraction (PEF) from the EtOH extract of flowers and buds of Chrysanthemum indicum was evaluated on antinociception in mice using chemical and thermal models of nociception. PEF administered orally at doses of 188 and 376mg/kg produced significant inhibitions on chemical nociception induced by intraperitoneal acetic acid, subplantar formalin or capsaicin injections and on thermal nociception in the tail-flick test and the hot plate test. In the pentobarbital sodium-induced sleep time test and the open-field test, PEF neither enhanced the pentobarbital sodium-induced sleep time nor impaired the motor performance, indicating that the observed antinociception was unrelated to sedation or motor abnormality. In a measurement of core body temperature, PEF did not affect temper...
The expression of motor activity levels in response to novel situations is under complex genetic and environmental control. Several genetic loci have been implicated in the regulation of this behavioral phenotype, but their relationship to epigenetic and epistatic interactions is relatively unknown. Here, we report on a quantitative trait locus (QTL) on mouse chromosome 1 for novelty-induced motor activity in the open field, using chromosome substitution strains derived from a high active host strain (C57BL/6J) and a low active donor strain (A/J). The QTL for open field (horizontal distance moved) peaked at the location of Kcnj9, however, QTL detection was initially masked by an interplay of both grandparent genetic origin and genetic co-factors influencing behavior on chromosome 1. Our fi...
The conceptual design for MCP to be installed in the integral reactor SMART was carried out. Canned motor pump was adopted in the conceptual design of MCP. Three-dimensional modeling was performed to visualize the conceptual design of the MCP and to check interferences between the parts. The theoretical design procedure for the impeller was developed. The procedures for the flow field and structural analysis of impeller was also developed to assess the design validity and to verify its structural integrity. A computer program to analyze the dynamic characteristics of the rotor shaft of MCP was developed. The rotational speed sensor was designed and its performance test was conducted to verify the possibility of operation. A prototypes of the canned motor was manufactured and tested to confirm the validity of the design concept. The MCP design concept was also investigated for fabricability by establishing the manufacturing procedures. 41 refs., ...
Ceramic ball bearings of silicon nitride are used for hard disk drive (HDD) spindle motors, to increase seed, reliability and memory capacity of the HDDs. Silicon nitride ceramics have advantages of lightweight, high strength and hardness over the conventional steel for bearings, but is expensive. A new process of high cost performance has been developed for mass production of the small-size ceramic balls. The company plans to apply these bearings to higher devices, e.g., servers, for the time being, and to expand the applicable areas, e.g., common devices and other small-size motors. The ceramic bearings have been developed jointly with Koyo Seiko Co. Ltd. (translated by NEDO)
Examination is made of the main features of the physical and chemical preignition processes within homogeneous mixtures of air and gaseous fuels, such as propane, methane and hydrogen in a motored engine, while employing detailed chemical kinetics in a one zone analytical model. The changes in the compression temperature and pressure due to the admission of gaseous fuels, energy release during the preingition reactions and the contributions of heat transfer and residual gases to the preignition reaction activity were followed over a number of consecutive cycles until the occurrence of autoignition. Some of the observed differences in engine behaviour when operating on methane, propane and hydrogen were discussed with particular reference to the observed trends in dual fuel engine operation. Calculated results showed good agreement with some corresponding experimental trends. 14 refs., 9 figs.
As part of the EPRI Motor-Operated Valve (MOV) Performance Prediction Methodology, a System Flow Model (SFM) has been developed to determine the differential pressure (DP) across MOVs as they are stroked in typical power plant systems. Input to the SFM includes valve flow characteristics (such as flow coefficient) and system characteristics (such as pump head/flow curve). The primary output is differential pressure across the valve at each stroke position. The SFM was validated by comparison with test data from the EPRI Flow Loop Test Program. In this study, we calculated DP using SFM and performed DP test for four MOVs. Compared between calculated DP and test DP of four MOV, respectively good agreements are found. (author). 6 refs., 9 figs., 1 tab.
According to the development of power electronic element (GTO, IGBT) nd material for electrical machines (permanent magnet, super conductor), the technology for electrical machines is now a day rapidly developing. here with, a novel electrical machine, based on the new conception of transverse flux configuration leads to a considerable increase in power density and enables simultaneously high efficiency.The transverse flux machine with PM excitation will be applied to gearless direct drives for railway traction system. The designed and measured performance of transverse machine for railway traction system revealed a great potential of system improvements to reduce linear motor mass. (author). 10 refs., 14 figs., 3 tabs.
The exchange of Eu[sup 3+] for Na[sup +] cations into the sodalite cages of X zeolite (Eu[sub 25]Na[sub 11]X) leads selectively to the isomerization reaction of cyclopropane to propylene. The latter reaction is catalyzed by Broensted acid sites with an apparent activation energy of 10.6 kcal/mol. Sorption measurements of cyclopropane and propylene with Eu/NaX and NaX zeolites at 40 C support the view that Na[sup +] cations might be considered as sites for sorption of these molecules. Force fields created by Eu[sub 4]O[sup 10+] present in Eu/NaX zeolite may affect sorption. On the other hand, Broensted acid sites in Eu/NaX enhance sorption of cyclopropane and propylene at 40 C. Chemisorption of propylene on the Broensted acid sites of Eu/NaX is reversible and may occur via a propylene carbenium cation intermediate. Small amounts of hexene are formed during this sorption. The amount of Broensted acid sites in the present Eu/NaX is at least 0.6 mmol/g cat.
A brain weight deficit of about 70 mg was induced at doses of approximately 75-mGy and a deficit of 60 mg was induced at 100 mGy. This confirms the effects projected and observed by Wanner and Edwards. Although the data do not demonstrate a clear dose-response relationship between the 75-mGy and 100-mGy groups, the data are statistically consistent with a dose-response effect because of the overlapping confidence intervals. The lack of a statistically significant observation is most likely related to the small difference in doses and the limited numbers of animals examined. There are several factors that can influence the brain weight of guinea pig pups, such as caging and housing conditions, the sex of the animal, and litter size. These should be taken into account for accurate analysis. Dam weight did not appear to have a significant effect. The confirmation of a micrencephalic effect induced x rays at doses of 75-mGy during this late embryonic stage of ...
The work presented in part 1 of this study established that the sorption of anhydrous HX into dehydrated Na{sub 56}Y progresses through a sequence of steps involving HX ionization and charge separation, oxygen framework protonation, formation of {alpha}-cage confined cation-anion contact ion pairs, and proton solvation by HX. A logical extension, which is the subjected of this study, concerns the effect of extraframework alkali metal cation type (M = Li{sup +}, Na{sup +}, K{sup +}, Rb{sup +}, Cs{sup +}) on the sorption process. The question of the acidity of proton-loaded zeolites compared to Broensted acid zeolites is addressed by using probe reactions with weak bases like ethane and cyclopropane. Additional insight into these systems is also obtained from a quantitative comparison of the kinetic and thermodynamic activation parameters for the dehydrohalogenation of proton-loaded zeolites exemplified by (HX){sub 8}Na{sub 56}Y relative to the decationization ...
Here we describe the use of low energy plasma immersion with active screen as a convenient approach for polypropylene (PP) surface modification. Employing a stainless steel cathodic cage coated with carbon in order to prevent the sputtering of iron from the grid and its deposition onto the polymer sample, the physical chemical properties of PP surface could be effectively modified through the plasma-induced incorporation/formation of nitrogen- and oxygen-containing species. The areal densities of these elements depended on the plasma excitation source, as determined by Rutherford backscattering spectrometry (RBS). Newly formed C-O, C-N, and C=O/O=C-O/N-C=O bonds along with C-C linkages from the PP backbone were identified at the near surface region of the specimens by X-ray photoelectron spectroscopy (XPS). The insertion of such polar reactive functionalities was further confirmed by a substantial decrease in the water contact angle upon plasma treatment. Scanning ...
The main LHC superconducting magnets (dipoles and quadrupoles) use Rutherford type cables, stabilized electrically and thermally with copper profiles. The portions of cables are connected to each other by a soft soldering technique (Sn96Ag4) with an overlapping length corresponding to one pitch of the superconducting strands. The splice constitutes a "composite" structure with the interchanging layers of Sn96Ag4 and NbTi superconductor, located inside a Cu cage. In order to ensure a high level of reliability (failure probability not exceeding 10-8) for some 10000 connections in the LHC, a non-destructive technique to check the quantity of solder in the joint is foreseen. The technique is based on a gamma ray source (241Am) and the detection is position-sensitive in the transmission mode. Scintillating detectors of gamma rays are used and their accumulated length corresponds to the length of the radioactive source (120 mm). The method can be used in-situ, the ...
Physicochemical and benthos data were collected from 12 marine monitoring stations in Daya Bay, during 2001-2004. 12 stations in Daya Bay could be grouped into three clusters: cluster I consisted of stations in the southern part of Daya Bay (stations S1, S2 and S6); cluster II consisted of stations in the cage culture areas (stations S3, S4, S5 and S8); cluster III consisted of stations in the southwest, the middle and the northeast of the Bay (stations S7, S9, S10, S11 and S12). Calculation with bivariate correlations between benthos and major physicochemical factors showed that the density of benthos in all stations correlated positively with temperature, DO, pH, NH4-N, SiO3-Si, SiO3-Si /PO4-P and chlorophyll a and was negatively correlated with salinity, Secchi, COD, NO3-N, NO2-N, TIN, ...
A complete macromolecule modeling package must be able to solve the simplest structure prediction problems. Despite recent successes in high resolution structure modeling and design, the Rosetta software suite fares poorly on deceptively small protein and RNA puzzles, some as small as four residues. To illustrate these problems, this manuscript presents extensive Rosetta results for four well-defined test cases: the 20-residue mini-protein Trp cage, an even smaller disulfide-stabilized conotoxin, the reactive loop of a serine protease inhibitor, and a UUCG RNA tetraloop. In contrast to previous Rosetta studies, several lines of evidence indicate that conformational sampling is not the major bottleneck in modeling these small systems. Instead, approximations and omissions in the Rosetta all-atom energy function currently preclude discriminating experimentally observed conformations from de novo models at atomic resolution. These molecular "puzzles" should serve as ...
In situ toxicity tests were designed for Ceriodaphnia dubia and Chironomus tentans as part of a larger study designed to assess the effectiveness of constructed wetlands for the treatment of wastewater produced by oil production at Suncor OSG. The artificial wetlands were 50m long by 3m wide, with three replicates of the control and the treatment. Each wetland had four sample sites equidistant along its length, creating a gradient of treatment from site A being the most toxic to site D being the least toxic. Each test was conducted twice during the summer of 1994. Both the Ceriodaphnia and Chironomus test cages were a flow through design to allow for maximal exposure to the water within the wetlands. Mortality and reproduction were used as endpoints for Ceriodaphnia, whereas mortality and growth were used as endpoints for the Chironomus test. Test durations were fifteen and ten days respectively. Chironomus had very high mortality along the entire wetlands whereas ...
A new type of ionization chamber with levitated electrode has been developed. In this ionization chamber, an ion-collection electrode levitates in the air without getting any physical support from the insulator. The electrode is charged by an electrostatic charger without physical contact. The charge of the electrode is read out at a Faraday cage periodically at a given time interval without physical contact. Because its electrode levitates, the ionization chamber produces no background current caused by leaks or piezo current. In addition, as the charging of its electrode and the read-out of its charge are carried out without physical contact, no irregular charge or contact potential difference due to the chattering between electrode and contact point occurs. Through experiments, it was found that this ionization chamber was able to measure the {gamma}-ray dose such as the environmental radiation with a high degree of sensitivity. The minimum detectable value of ...
Calcined and sulfided Ni-Mo catalysts supported on ultrastable Y zeolite (USY), NaY zeolite, mordenite, and ZSM-5 were studied by high-resolution electron transmission microscopy (HRTEM) with selected-area electron diffraction (SAED) and energy-dispersive spectroscopy (EDS). Ni and Mo oxide aggregates were rarely observed in the USY-supported Ni-Mo catalyst, indicating that most of Ni and Mo may be incorporated into USY, e.g., supercavities and possibly sodalite cages. However, there were a large number of {alpha}-NiMoO{sub 4} aggregates of different particle sizes in NaY-, mordenite-, and ZSM-5-supported catalysts, and the mordenite-supported catalyst also contained MoO{sub 3} crystals. The {alpha}-NiMoO{sub 4} may be attached to the surface of substrates as individual particles or needle aggregates, it may be disseminated into mordenite particles, or it may even form an isolated sphere (in Ni-Mo/NaY) or a needle (in Ni-Mo/ZSM-5) aggregates. Thus, most of Ni and ...
We devised a three-dimensional method for estimation of cerebral development and myelination which measures cerebral volume using MRI. Accuracy of the system was estimated using cadaver brains. The mean percentage error in the calculated volumes compared with the real volumes was 2.33 %, range 0.00-5.33 %. We applied the method to the volume of both cerebral hemispheres (CH), basal ganglia, thalamus and internal capsule (BT), and myelinated white matter (WM) in 44 neurologically normal individuals (4 months to 28 years of age), 13 patients with spastic motor disturbances (2-25 years of age), and 9 patients with athetotic motor disturbances (2-23 years of age). In the neurologically normal cases, the volumes of CH, BT and WM increased with age; the volume of MW more slowly than that of CH. In cases with spastic motor disturbances, the volumes of CH, BT and WM were between -1.4 and 3.5 SD, -1.0 and -3.5 SD, and 0.0 and -5.2 ...
ATP is synthesized by ATP synthase (FOF1-ATPase). Its rotary electromotor (FO) translocates protons (in some organisms sodium cations) and generates torque to drive...Full Text Available
A brief article gives an update on the commercial exploitation of superconductivity by the American Superconductor Corporation. Potential applications include transmission and distribution, motors, magnetic storage systems, current limiters and transport. The company have produced a kilometre long, ''wrappable'' cable capable of carrying thousands of amps when operating at a temperature of below -140[sup o]C. (UK)
This EPRI sponsored report describes factors that influence the selection of drives in process industry. These factors include economics, safety aspects, speed control and the plant steam balance. Since the economics play a key-role in the decision, this report provides a quick way of estimating the economics of replacing steam turbines with electric motors. The tools to carry out economic analyses have been provided in the form of graphs and nomographs for quick estimation.
Electric cars are a clean and noiseless alternative to vehicles with combustion engines for journeys in cities and their environs. In recognition of this, ABB has developed an efficient electric drive system featuring modern power electronics and a high-energy, sodium-sulphur battery. The energy-to-weight ratio of this battery is four times that achieved with conventional lead-acid batteries. To recharge the battery, a charger mounted next to the motor has only to be connected to a household power socket.
A semiautomatic system for measurements of nuclear tracks in nuclear emulsion is described. The microscopic image of a particle track is picked up by a video camera. The video picture is digitized in real time. The picture analysis is done via software. The microscope is equipped with a stepping motor driven stage which is also computer-controlled.
Electric cars run silently and produce no exhaust fumes. In cooperation with other companies BBC has developed a compact drive system for the VW Golf comprising a battery-powered separately excited DC motor, transmission, control system and setpoint devices. With a range of 57 km and a top speed of 90 km/h, the electric Golf lends itself well to city driving.
Previous studies reveal that dark-induced closure of Samanea leaflets is accompanied by H+ secretion from flexor motor cells. We now report that flexor tissue excised in...Full Text Available
The device is made by a tool at the end of a flexible cable, a motor for the rotation of the flexible, a linear drive with a guide for it between the winder and the tube.
At HMC, fundamental research on the hydrogen fueled engine and vehicle has been carried out. For this engine, solenoid driven injector is used to supply gaseous hydrogen into the cylinder and various operating parameters have been changed to study the combustion characteristics of hydrogen. After these experiments on the engine, a hydrogen fueled vehicle has been constructed and it is controlled by an ECU. The amount of emission from the hydrogen vehicle with stoichiometric operation is less than 1/3 of the ULEV legislation.
RP-1 is a long-established hydrocarbon fuel that continues to be widely used as the kerosene component in rocket propulsion systems. The desire in recent years to use rocket motors many times, rather than a single time, has led to reformulations of RP-1. ...
Metadata can be used to support accessibility in connection with improved discovery. ...certain metadata elements provide information about what capabilities are needed--either perceptual-motor, cognitive, socio-economic or geographic--to make use of a resource. This cam improve the ability of users who are disadvantaged in these ways to find resources that meet their needs--and avoid ones [resources] that do not.
Motor proteins couple steps in ATP binding and hydrolysis to conformational switching both in and remote from the active site. In our kinesin·AMPPPNP crystal structure, closure of the active...Full Text Available
Laser-Doppler anemometry was used to investigate mean flow and turbulence fields in a direct injection diesel engine, motored at speeds of 1500, 2250 and 3000 rev/min. Both cycle-resolved and ensemble-averaged measurements were made in the upper part of the cylinder during the inlet and compression strokes. The cycle-resolved measurements in the inlet stroke are discussed in this paper.
Rising oil prices are a problem for the motor car industry. Now, an ambitious project has been launched in California which may become a serious competitor to gasoline and diesel engines: The Tesla Roadster, which is fuelled from simple wall sockets. (orig.)
The ECOTEC is a mass-efficient gasoline DOHC 4-valve per cylinder engine with balance shafts, chain driven camshafts and roller finger followers with hydraulic lash adjusters for valve actuation. It has lightweight aluminium components such as camcover, cylinder head, cylinder block, lower crankcase and structural oil pan. Other features include composite intake manifold and a coil-on-plug ignition cassette. The ECOTEC combustion system and engine architecture are optimized for low engine out and tail pipe emissions. It also includes several designed-in 'green' features for environmental benefits. The product design, development and validation process drew upon the best knowledge and practices available worldwide both inside and outside General Motor. The manufacturing systems were also designed by leveraging the best available knowledge around the world resulting in implementation of world class processes and error proofing to achieve the ...
Power output of a hydrogen-diesel dual-fuel engine is limited by the onset of knock as the percentage of heat input derived from hydrogen increased beyond a certain limit. Earlier work carried out at the Internal Combustion Engines Laboratory, Indian Institute of Technology, Madras, indicates that this knock sets in when the induced hydrogen exceeds about 60% of input energy at a pilot diesel quantity of 30% of full load diesel amount. At higher rates of hydrogen induction, the richer hydrogen-air mixture is more prone to knocking. Hardly any information is available on the possibilities of improving the knock limited power output of a hydrogen-diesel dual-fuel engine. Water can serve as a powerful internal coolant in decreasing the unburned mixture temperature because of its high latent heat. This paper presents the results of our investigation on improving the knock limited power output when water is inducted with the intake charge of a ...
Ethidium bromide (EB) and ultraviolet light (UV) in combination are known to produce a synergistic induction of 'petite' mutants in yeast. Two other agents were combined with EB, 3-Carbethoxypsoralene (3 CPs) activated by 365 nm light or #gamma# rays. EB in combination with 3 CPs also resulted in an enhanced production of 'petite' mutants. After the photoaddition of 3 CPs in exponential phase cells, recovery of the 'petite' mutation during dark liquid holding was inhibited by the presence of EB producing an enhanced number of 'petite' mutants. The behavior of mitochondrial antibiotic resistance markers after individual and combined treatments with EB and 3 CPs indicates a random loss of markers after EB and a preferential loss of a certain region for the 3 CPs photoaddition. The combination of the two agents leads to an additivity of total drug marker losses rather than a synergistic loss. The combination of EB with #gamma# rays produced no enhancement in 'petite' ...
A technique and a particular apparatus for an inductive measurement of critical currents as a function of temperature and magnetic field in thin-film superconductors are described. The technique has been found to be particularly useful for high-field A-15 compounds 2 to 3 ..mu..m thick. Samples with lower critical current densities would have to be correspondingly thicker to measure over the same broad range of temperature and field. The design of the apparatus is detailed showing that the film can be taken directly from the deposition chamber and mounted without electrical contacts so samples can be changed easily. The principles of operation are developed based on the Critical State Model. These principles are tested by measurements which verify that the measured value of critical curent is independent of the amplitudes and frequency of the small ac magnetic field which is added to a much larger quasistatic field. The inductive measurements ...
The addition of paraquat (methyl viologen) to a growing culture of Escherichia coli K-12 led within 1 hr to a 10- to 20-fold increase in the level of endonuclease IV, a DNase for apurinic/apyrimidinic sites. The induction was blocked by chloramphenicol. Increases of 3-fold or more were also seen with plumbagin, menadione, and phenazine methosulfate. H_2O_2 produced no more than a 2-fold increase in endonuclease IV activity. The following agents had no significant effect: streptonigrin, nitrofurantoin, tert-butyl hydroperoxide, #gamma# rays, 260-nm UV radiation, methyl methanesulfonate, mitomycin C, and ascorbate. Paraquat, plumbagin, menadione, and phenazine methosulfate are known to generate superoxide radical anions via redox cycling in vivo. A mutant lacking superoxide dismutase was unusually sensitive to induction by paraquat. In addition, endonuclease IV could be induced by merely growing the mutant in pure O_2. The levels of endonuclease ...
Experimental and theoretical research has been conducted jointly at the Livermore and Los Alamos National laboratories on dc electromagnetic railgun Lorentz accelerators. Pellets weighing a few grams to tens of grams have been launched at velocities up to better than 11 km/s. The research is addressed to attaining repeated launches of samples at hypervelocity in target impact experiments. In these experiments, shock-induced pressures in the tens of megabars range are obtained for high pressure equation-of-state research. Primary energy sources of the order of several hundred kJ to a MJ and induction currents of the order of 1 or more MA are necessary for these launches. Erosion and deformation of the conductor rails and the accelerated sample material are continuing problems. The heating, stress, and erosion resulting from simultaneous imposition of rail induction current, dense plasma (armature) interaction, current distribution, magnetic ...
Model construction of the laboratory scale superconducting fault current limiter circuit (SFCL) has been performed. The SFCL is fault current limiter and used as electric network security. It mainly consists of a copper coil, a superconducting ring and an iron core that are concentrically arranged. The SFCL circuit is essentially a transformer where the secondary windings are being replaced by the ring of YBa_2Cu_3O_7_-_x superconductor (HTS). The ring has critical transition temperature Tc = 92 K and critical current Ic = 3.61 A. Characterization of the SFCL circuit is simulated by ANSYS version 5.4 software. The SFCL circuit consists of load and transformer impedances. The results show that the inductions of magnet field flux in the iron core of primer windings and ring disappear to one other before fault state. It means that impedance of the transformer is zero. After the condition a superconductivity behavior of the ring is disappear so that the impedance of ...
In response to a heat shock, the yeast Saccharomyces cerevisiae undergoes a large increase in its resistance to heat and, by the induction of its recombinational DNA repair capacity, a corresponding increase in resistance to radiation. Yeast which lack mitochondrial DNA, mitochondria-controlled protein synthetic apparatus, aerobic respiration, and electron transport (rho/sup 0/ strain) were used to assess the role of O/sub 2/, mitochondria, and oxidative processes controlled by mitochondria in the induction of these resistances. We have found that rho/sup 0/ yeast grown and heat shocked in either the presence or absence of O/sub 2/ are capable of developing both radiation and heat resistance. We conclude that neither the stress signal nor its cellular consequences of induced heat and radiation resistance are directly dependent on O/sub 2/, mitochondrial DNA, or mitochondria-controlled protein synthetic or oxidative processes.
OBJECTIVE:- To determine the effectiveness and safety of short-term treatment of infliximab (IFX) in a group of Chinese patients with active Crohn's disease (CD). METHODS:- Patients with established diagnosis of active CD were treated with IFX intravenously with a dose of 5-mg/kg at week 0, 2, 6. Clinical assessments were performed at baseline (week 0) and every week after IFX infusion until 8 weeks after the induction dose. RESULTS:- Fourteen patients (nine male, five female) with a mean age of 29.7 years (range from 15 to 65 years) were included in the analysis. The mean subjective scores were decreased from 2.85--0.57 at baseline to 1.3--0.4 at week 14 (P-CONCLUSIONS:- Treatment with three infusions of IFX at a dose of 5-mg/kg was effective for induction of remission for active CD patie...
In defining criteria for good protection against ionizing radiation, it is important to assess quantitatively the likely risk of any radiation exposure. The 'somatic' risks to the individual result mainly from induction of cancer in the organs irradiated, and these risks can now be estimated on the basis of numerous detailed epidemiological surveys of exposed human populations. Estimates of the risk of hereditary effects, from genetic changes induced in germ cells, are based largely on the frequency with which such effects are induced in other species. In both cases the risk at very low dose can be inferred using knowledge of the way in which radiation damage is caused in tissues. Coherent systems of radiation protection are based on a restriction of doses to the whole body and to individual organs, such that the induction of cancer and genetic harm is infrequent, and the threshold dose for causing other, 'non-stochastic', effects is not ...
We present the design, analysis, and results of the high brightness electron beam experiments currently under investigation at Sandia National Laboratories. The anticipated beam parameters are the following: energy 12 MeV, current 35 endash 40 kA, rms radius 0.5 mm, and pulse duration 40 ns full width at half-maximum. The accelerator is SABRE, a pulsed linear inductive voltage adder modified to higher impedance, and the electron source is a magnetically immersed foilless electron diode. 20 endash 30 T solenoidal magnets are required to insulate the diode and contain the beam to its extremely small-sized (1 mm) envelope. These experiments are designed to push the technology to produce the highest possible electron current in a submillimeter radius beam. Design, numerical simulations, and experimental results are presented. copyright 1997 American Institute of Physics.
Allogeneic stem-cell transplantation (SCT) is potentially curative therapy in AML by providing both dose-intensive chemo-radiotherapy and induction of graft-versus-leukemia (GvL) effect. Historically, more emphasis was given to the intensity of conditioning. Over the last decade the pendulum turned more towards induction of GvL as the primary goal. A plethora of non-myeloablative (NMA) and reduced-intensity conditioning regimens (RIC) were introduced trying to reduce transplant-related toxicities and allow SCT in elderly and medically infirm patients. In addition, reduced-toxicity myeloablative regimens (RTC) based on fludarabine and myeloablative alkylating-agent doses were designed to allow safer administration of dose-intensive therapy. Conditioning dose-intensity is highly correlated w...
Synergism has been observed during inhibiting initiated oxidation of styrene or tetralin by organic phosphites in the presence of complex compounds of some transition metals. The results are given of non-additive intensification of antioxidative activity of triphenylphosphite (TPP) and tri-(4-methyl-6-tert.-- butyl)-phenyl-phosphite (TMBP) in the process of initiated oxidation of styrene or tetralin with addition of acetylacetonates of cobalt and vanadyl. During styrene oxidation, inhibition of the reaction with chelate complex of vanadyl is weakened considerably when phosphite is added into the reaction system. During tetralin oxidation, postcatalytic (or branched) oxidation is observed only for large concentration of vanadyl complex. Addition of TPP to above complex sharply increases the induction period. When the induction period is completed, oxidation of tetralin follows the mechanism of usual, i.e. initiated, reaction.
In this article a production method of a magnetorheological suspension composed with silicon steel particles of size 0.1-0.15 mm and 4% silicon content is described. Steel particles were dispersed in a conducting carrier of a by mixture of graphite particles with size 2-5 {mu}m and cedar wood oil. The filling factor of the suspension with the silicon steel particles and with graphite particles amounted to 0.25-0.40. Samples of this suspension were placed in a rectangular vessel with electrodes and used for the investigation of the Hall effect in magnetic field with induction 0-8 T, generated by Bitter-type magnet. A non-linear dependence of Hall voltage on the induction of the applied magnetic field and a hysteresis loop of this voltage in the shape of inclined digit eight were found. The causes of the observed effects is the ordering of silicon steel particles and graphite particles along the side of magnetic field lines.
The effects of spin diffusion on the free induction decay (FID) of protons associated with the noncrystalline domains of two polymers, polyethylene and blended Nylon 66 (ZYTEL-408), have been examined using Goldman--Shen NMR pulse sequence ((1/2)..pi..x-t/sub 0/-(1/2)..pi..x-bar-tau-(1/2)..pi..x-t). At tau< or approx. =100 ..mu..s, the FID is drastically distorted from the exponential form while at longer tau(tau> or approx. =500 ..mu..s) an exponential FID is observed; but its transverse spin relaxation rate is smaller than that of the FID obtained after a single (1/2)..pi..x pulse and approaches this value at the limit of large tau. These findings are interpreted in terms of the theory of rapid spin diffusion. The spatial variation in the spin relaxation rate within the noncrystalline domain is inferred.
A new method for analysis and design of smoothing reactances utilising two-dimensional planar models is presented in this paper. Inductance and magnetic flux density are calculated, and their results compared with those measured experimentally. The results obtained are good if compared with those measured once the machine have been built. Moreover, the method herein developed is applied to the calculation of air gap lengths in terms of the desired current and inductance. The kind of reactances studied presents windings in both limbs and air gaps in the four corners (joint of limbs and yokes). The main contribution of this paper is the presentation of a method of industrial application, to be easily developed, with a very important reduction in the time of machine calculation (due to the decrease in the number of nodes and elements compared with the three-dimensional model) for the determination of the air gap length in smoothing reactances. ...
Finding interesting rule in the sixth strategy step about threshold control on generalized relations in attribute oriented induction, there is possibility to select candidate attribute for further generalization and merging of identical tuples until the number of tuples is no greater than the threshold value, as implemented in basic attribute oriented induction algorithm. At this strategy step there is possibility the number of tuples in final generalization result still greater than threshold value. In order to get the final generalization result which only small number of tuples and can be easy to transfer into simple logical formula, the seventh strategy step about rule transformation is evolved where there will be simplification by unioning or grouping the identical attribute. Our approach to measure interesting rule is opposite with heuristic measurement approach by Fudger and Hamilton where the more complex concept hierarchies, more ...
Carcinogenesis is now generally recognized to be an important detrimental effect in man after low dose irradiation. The carcinogenic action of ionizing radiation is clearly demonstrated after exposure to relatively high doses (in excess of 0.5 Gy) but for lower dose levels reliable direct observations are not available. With the introduction of special protocols for the performance of large scale screening programs by mammography the average absorbed dose in glandular tissue in the average breast can be restricted to a value of 3 mGy per mammogram. The risk for tumor induction after exposure to these low doses can never be established from human epidemiology. In order to investigate the risk of repeated exposure to small dose of ionizing radiation the induction of mammary tumors has been investigated in rats of the WAG/Rij strain after single and fractionated irradiations with gamma-rays. (author). 8 refs., 3 figs.
Maintenance of genomic integrity in embryonic cells is pivotal to proper embryogenesis, organogenesis and to the continuity of species. Cultured mouse embryonic stem cells (mESCs), a model for early embryonic cells, differ from cultured somatic cells in their capacity to remodel chromatin, in their repertoire of DNA repair enzymes, and in the regulation of cell cycle checkpoints. Using 129XC3HF1 mESCs heterozygous for Aprt, we characterized loss of Aprt heterozygosity after exposure to ionizing radiation. We report here that the frequency of loss of heterozygosity mutants in mESCs can be induced several hundred-fold by exposure to 5-10Gy of X-rays. This induction is 50-100-fold higher than the induction reported for mouse adult or embryonic fibroblasts. The primary mechanism underlying the...
Abstract Herpesvirus saimiri (HVS) causes acute lymphoma and leukemia upon experimental infection of various monkey species. HVS strain C488 is also capable of transforming human T-lymphocytes to stable growth in culture. The most susceptible species for oncogenesis are New World primates, in particular the cottontop tamarin (Saguinus oedipus). However, Old World monkeys such as macaques are the most used animal model for the close-to-human situation. The limited data on HVS infection in Old World monkeys prompted us to investigate susceptibility to infection and disease induction by HVS in macaques. After having established that rhesus macaques can be infected productively, and that rhesus T-cells can be transformed in vivo by HVS, we observed induction of lymphoma in all inoculated anima...
In tomato crop, the induction of resistance emerges as an important alternative for achieving the reduction of chemicals in disease control. This study aimed to evaluate the ability of 28 Trichoderma isolates to promote the growth of tomato seedlings and to induce systemic resistance (ISR) against Xanthomonas euvesicatoria and Alternaria solani, the causal agents of bacterial spot and early blight, respectively. Twelve isolates promoted the increase of plant dry matter mass (DMM) above 100%, showing the great potential of these strains. All isolates were able to colonize the root system of tomato plants. The plant growth-promoting isolates were further evaluated for potential elicitation of ISR. Treatment of the soil with all Trichoderma isolates provided protection in tomato plants from 2...
With appropriate circuit resistance and inductance and sufficient stored energy, discharging a charged human body or component through an exploding bridgewire (EBW) detonator may cause the detonator to function or may damage the detonator. We have studied the effects of electrostatic discharge (ESD) on a number of exploding bridgewire detonators which were subjected to discharges which passed directly through the bridgewires (pin-to-pin), as well as discharges which passed from the bridge to the metal case of the detonator (pin-to-case). We have performed calculations to determine the values of inductance and resistance for which burst and melt may occur for given ESD sources, using a phenomenological model of bridgewire burst in a computer code called FIRESET. Bridge melt was computed using the same computer code, but using experimental values of bridge resistivity and specific heat up to melt. 13 refs., 5 figs.
The production method of the elastic composite containing ferrous particles and titanium barium particles dispersed in the porous silicone matrix is described in this article. Since it contains ferrous and titanium barium particles, this composite shows magnetorheological and also electrorheological properties. The electrostriction of composite samples in the electric field with maximal intensity 1.5x10{sup 6} V/m was investigated. The magnetostriction in the magnetic field with maximal induction 1 T was also investigated. It was found that samples elongate with increased electric field intensity, and the magnetic field induction was detected. By increasing the samples' elongation with increase of ferrous particles, titanium barium particles and pores number were also detected. In the investigated division of the electric and magnetic field the elongation changed in a linear way. The maximal elongation achieved was 1.59%.
We have constructed a mathematical model that describes the coherent spontaneous radiation of a macroscopically filled exciton mode. We have demonstrated qualitatively ways in which a coherent subsystem of excitons can be formed. When this occurs under the influence of an external coherent source, exciton free induction occurs, while in the case of a spontaneous transition of the excitons to a coherent state through freezing of the reservoir of intermolecular interactions superradiance occurs. We have concluded that superradiance in the system of Frenkel excitons is possible under the influence of the non-Dicke mechanisms of self-induction of correlations, when the dipole transition moments of the individual atoms are coupled into a single macroscopic effective spin through their electrostatic interaction, this being analogous to the ordering of magnetic dipole moments in a ferromagnet.
The design and operating principle of a small (50 mm in diameter and 100 mm in height) ???-73C vacuum spark gap are described. It is shown that it can be efficiently switched using a control circuit with a low (?900 V) supply voltage, which is based on an inductive energy storage and a diode opening switch that forms a high-voltage igniting pulse with a rise time of nanosecond duration. The ???-73C switching process is investigated at different rise times of igniting voltage pulses and different igniting current amplitudes. The results of tests of the spark gap operating in regimes of switching current pulses with an amplitude of 12 kA and a rise time of 800 ns are presented.
The FVM-LES-acoustic analogy method (FVM-LES-AAM), which is a hybrid prediction technique for the acoustical property computation, is presented and performed in this paper. The FVM-LES-AAM was developed by combining the finite volume method (FVM), the large eddy simulation (LES), and the Ffowcs Williams-Hawkings analogy algorithm (FWH-AA). To predict the acoustical properties of induction cookers, the FVM is used for discretizing the calculation field and building numerical equations, and the LES and FWH-AA are performed for computing the sound sources and predicting the far-field sound, respectively. Using the FVM with the unstructured grids method to discretize the control equation of Navier-Stokes was introduced for illuminating the above numerical simulation procedure. To prove the FVM...
This report describes the test of a dynamic phase compensation unit for a wind turbine with directly connected induction generators. The compensation unit is based on thyristor switched capacitors, where conventional wind turbine compensations use mechanical contactors to switch the capacitors. The influence on power quality analysed, and influence on component lifetime is discussed. Besides, simulation models in Matlab/Simulink are presented, including a flicker meter model. (au)
The motion of an accelerated charge in a vacuum is analyzed, via the superposition principle and Fourier analysis, into uniform-motion components, which include bradyonic as well as tachyonic contributions. It is shown that the former contribute only to the induction fields whereas the latter are the source of the radiation emitted by the charge, via the Sommerfeld-Cerenkov mechanism. This result calls for a reexamination of some recently formulated theories of superluminal particles.
Purpose.To report the increased production of extracellular transforming growth factor β-induced protein (TGFBIp) by human corneal epithelial cells (HCECs) after induction...Full Text Available
We review the status of free electron laser (FEL) research being conducted at LBL and LLNL as part of a broader program of research on two beam accelerators (TBAs). Induction accelerator-driven FELs for use as power sources for high-gradient accelerators are discussed, along with preliminary cost estimates for this type of power source. Finally, a promising new version of an FEL/TBA is described. 25 refs., 1 fig., 3 tabs.
Pacini (1973) has considered basic theoretical expectations regarding the magnetic dipole radiation and unipolar induction of pulsars, taking into account observational results. The present investigation is concerned with the difference between the two braking mechanisms. Attention is also given to a statistical study involving a comparison of the two braking mechanisms with observations. The study makes use of the observational data for the distribution of apparent beamwidth, and a geometrical method. The obtained results agree with the theory of magnetic dipole radiation.
1. The induction of long-term potentiation (LTP) was investigated in the rat dentate gyrus in the presence of ryanodine, an agent which is known to selectively bind to the ryanodine receptor (RyR) Ca2+...Full Text Available
A cDNA library was constructed from HL60 human promyelocyte poly(A)+ RNA harvested 3 h after induction of macrophage differentiation with 12-O-tetradecanoyl phorbol-13-acetate in the presence of cycloheximide....Full Text Available
From the frequency of diagnostic radiologic examinations and their radiation dose delivered to the population the risk of cancer induction and genetic damage is calculated on the basis of the risk factors given by the ICRP. Thus 0.38 % and 3 % of the total mortality for cancer and leukemia, resp., can be attributed to X-ray diagnostics. Chest examinations alone result in 0.07-0.7 damages per 100,000 persons depending on the imaging technique applied. (author).
This research has two main goals; (1) to quantify mechanisms for radon entry into homes of different types and to determine the fraction of indoor radon attributable to each source and (2) to model and calculate the dose (and therefore alpha particle fluence) to cells in the human and animal tracheobronchial tree that is pertinent to induction of bronchogenic carcinoma from inhaled radon daughters.
This report continues the studies of simplified methods, of magnetic diagnostics in application to TCA/BR tokamak. Here we study the accuracy of known formula for {beta}{sub 1} + l{sub 1}/2 determination from the poloidal magnetic field asymmetry. Errors of the diamagnetic measurements due to vibrations of the vacuum vessel are also considered. (author). 3 refs., 1 fig., 1 tab.
Primary leaves of 7- to 9-day-old etiolated seedlings of Phaseolus vulgaris L. var. Red Kidney infiltrated in darkness with aqueous solutions of α, α′-dipyridyl,...Full Text Available
BackgroundAfrican horse sickness virus (AHSV) causes a non-contagious, infectious disease in equids, with mortality rates that can exceed 90% in susceptible horse populations....Full Text Available
The use of irrigation systems in the proximity of high voltage transmission lines is increasing. This study examines the induced voltages and currents on a pivotal irrigation system operating under a 765 kV line. With a few simple precautions such as a system can be operated in complete safety. 1 ref.
PNAS-4, a novel pro-apoptotic gene activated during the early response to DNA damage, can inhibit proliferation via apoptosis when overexpressed in some tumor cells. Recent studies have indicated that honokiol can induce apoptosis, inhibit angiogenesis, and suppress tumor growth. In the present study, we investigated whether mouse PNAS-4 (mPNAS-4) could augment the apoptosis of tumor cells induced by honokiol in vitro, and whether the antiangiogenic activity of honokiol and induction of apoptosis by mPNAS-4 could work cooperatively to improve the antitumor efficacy in vivo. In vitro, mPNAS-4 inhibited proliferation of murine colorectal carcinoma CT26 and Lewis lung carcinoma LL2 cells through induction of apoptosis, and significantly augmented the apoptosis of CT26 and LL2 cells induced by honokiol. Compared with treatment with mPNAS-4 or honokiol alone, in vivo systemic administration of an expression plasmid encoding mPNAS-4 and low-dose ...
Dendritic cells (DC) are the most potent antigen-presenting cells and play a central role in the induction of antiviral immune responses. Recently, we have shown that monocyte-derived DC (MoDC) from...Full Text Available
The study examined the possibility for fuel ignition by spark discharge caused by induction effects under high voltage transmission lines. Theoretical background information on capacitive spark discharges and fuel ignition processes is given. Laboratory experiments were conducted to test the dependence of fuel ignition on three parameters: impedance in discharge path, multiple discharges, and larger electrode shapes. The results of these tests are discussed in terms of fuel ignition possibilities under high voltage transmission lines.
Occupational and environmental exposure to organic ligands, solvents, fuel hydrocarbons, and polychlorinated biphenyls are linked with increased risk of hematologic malignancies. DOE facilities and waste sites in the U.S. are contaminated with mixtures of potentially hazardous chemicals such as metals, organic ligands, solvents, fuel hydrocarbons, polychlorinated biphenyls and radioactive isotopes. A major goal of this project was to establish linkage between chemical/radiation exposure and induction of genomic damage in target populations with the capability to undergo transformation.
The objective of this study was to determine if genistein (GEN) modulation of the immune responses might contribute to the increased host resistances to tumors. A time-course study was performed...Full Text Available
Two cellular DNA regions representing common domains for proviral DNA integration ( Mlvi -1 and Mlvi -2) have been identified in Moloney murine leukemia virus-induced rat thymic lymphomas. Cellular...Full Text Available
Because of questions regarding current density and inductance estimates of the Atlas oil transmission line in the region where the vertical plates connect to the disk line, calculations using the 3D FE program Flux3d were initiated. Flux3d inductance values are nearly that estimated by D. Scudder. Calculations for three base designs of E. Ballard and D. Pierce were completed where several variations for each base design were used to determine the important parameters affecting inductance and to check inductance consistency. Flux3d showed for the first base design a very high current density of 36MA/m at the connection between the vertical and horizontal ground plates resulting in a magnetic pressure of 120 kpsi. The second base design modified this connection to reduce the current density to 20MA/m and 36 kpsi and for design 3 current density is 17MA/m. Maximum current density on the hot plates is ...
A class-V myosin, myosin V, one of 18 known classes of actin-based motor proteins, plays a role in transporting organelles within a cell. Unlike myosin-II, which functions as an assembly in the thick filaments of muscle, myosin V is a two-headed processive motor protein, which functions as a single molecule: myosin V performs many consecutive steps before it detaches from an actin filament accompanied by catalytic cycles of ATP (adenosine 5'-triphosphate) ase. The mechanism of such chemomechanical steps is explained by a 'Hand-over-hand model' in which two heads of myosin V alternately repeat single-headed and double-headed bindings with an actin filament. To investigate the binding state of myosin V at several key nucleotide states during ATP hydrolysis, we measured the mechanical properties of a single myosin V - actin complex by applying an external load with optical trap.
The set of laws developed and presented here is by no means exhaustive. Techniques have been present to aid in the development of additional scaling laws and to combine these and other laws to produce additional useful relationships. Some of the relationships produced here have yielded perhaps surprising results. Examples include the fifth order scaling law for electromagnetic motor torque and the zero order scaling law for capacitive motor power. These laws demonstrate important facts about actuators in small-scale systems. The primary intent of this introduction into scaling law analysis is to provide needed tools to examine possible areas of the research in small-scale systems and direct research toward more fruitful areas. Numerous examples have been included to show the validity of developing scaling laws based on first principles and how real world systems tend to obey these laws even when many other variables may potentially come into ...
Study was made on the city bus driven by the series hybrid system composed of a small ceramic gas turbine (100kW), generator and lead storage battery. Two driving modes were adopted, 10-driving mode and real driving mode assuming a certain bus route in Tokyo. The motor is driven mainly by generated power and additionally by battery power, however, the engine/generator system is controlled at an optimum operation point (driving mode and regenerating mode) with a maximum thermal efficiency considering depth of discharge. Design voltage of the battery had nearly no effect on fuel consumption, while its capacity as large as possible was desirable unless its weight has an adverse effect on the system. The real driving mode was lower in fuel consumption by 39% than the 10-driving mode. Since real fuel consumption is largely affected by recovery rate of regenerable energy, the operation point of the motor should be optimized according to driving mode. ...
In many facilities, energy management is simply a matter of managing the energy required for lighting and space conditioning. In many others, however, energy management is much more complex and involves large motors and controls, industrial insulation, complex combustion monitoring, unique steam distribution problems, significant amounts of waste heat, etc. Typical facilities offering large energy management opportunities include industrial facilities, large office and commercial operations, government institutions such as schools, hospitals and prisons. Such facilities generally have specialized industrial, commercial or institutional processes that incorporate many of the concepts covered in other chapters. These processes require thorough analytical evaluations to determine the appropriate energy-saving measures. This chapter provides some examples. In this chapter the authors present a suggested procedure for process energy improvement. Then, ...
Liquid pipeline codes generally stipulate placement of block valves along liquid transmission pipelines such as on each side of major river crossings where environmental hazards could cause or are foreseen to potentially cause serious consequences. Codes, however, do not stipulate any requirement for block valve spacing for low vapour pressure petroleum transportation, nor for remote pipeline valve operations to reduce spills. A review of pipeline codes for valve requirement and spill limitation in high consequence areas is thus presented along with a criteria for an acceptable spill volume that could be caused by pipeline leak/full rupture. A technique for deciding economically and technically effective pipeline block valve automation for remote operation to reduce oil spilled and control of hazards is also provided. In this review, industry practice is highlighted and application of the criteria for maximum permissible oil spill and the technique for deciding valve automation thus ...
This is a report on modification of a locomotive diesel engine to a dual-fuel engine to determine if the dual fuel engine in railway service will provide high performance, lower fuel and maintenance costs. After the locomotive was modified and the new governor and linkage were installed by General Motors at the BN's Northtown Diesel Shop near Minneapolis, the locomotive went through startup procedures. General Motors participated in startup. Some calibration, adjustments and minor piping changes were required but in general the problems encountered in startups were quite insignificant. The locomotive was connected to the load box (static test) during startup and at 720 RPM exceeded the required output for this test as established by the parties. Operation on straight oil over the range from idle through No. 8 throttle notch and on dual fuel from No. 5 through No. 8 throttle notch was smooth as was the transfer from oil to gas and from ...
This paper presents the application of hydraulic network analysis to evaluate the performance of butterfly valves in nuclear power plant applications. Required actuation torque for butterfly valves in high-flow applications is often dictated by peak dynamic torque. The peak dynamic torque, which occurs at some intermediate disc position, requires accurate evaluation of valve flow rate and pressure drop throughout the valve stroke. Valve flow rate and pressure drop are significantly affected by the valve flow characteristics and the hydraulic system characteristics, such as pumping capability, piping resistances, single and parallel flow paths, system hydrostatic pressure, and the location of the motor-operated valve (MOV) within the system. A hydraulic network analysis methodology that addresses the effect of these parameters on the MOV performance is presented. The methodology is based on well-established engineering principles. The application of this methodology ...
The aqueous fraction (AF) of an ethanolic extract from Chrysanthemum indicum was evaluated for analgesic activity in mice using chemical and thermal models of nociception. Given orally, AF at doses of 300 and 600 mg/kg produced significant inhibitions on chemical nociception induced by intraperitoneal acetic acid, subplantar formalin/capsaicin injections and on thermal nociception in the tail-flick test and in the hot plate test. In the pentobarbital sodium-induced sleeping time test and the open-field test, AF neither significantly enhanced the pentobarbital sodium-induced sleeping time nor impaired the motor performance, indicating that the observed analgesic activity was unlikely due to sedation or motor abnormality. In a measurement of core body temperature, AF did not affect temperature within 80 min. Moreover, the effective dose (600 mg/kg) also showed no toxicity within 7 days. These results suggested further that AF produced analgesic ...
Reviews types of hydraulic power shovels used in coal surface mines in the USA, FRG, Japan and other countries. Excavators of the first, second and third generation are compared. Hydraulic schemes of the excavators are compared. The following excavators are reviewed: the RH-75, RH-75C, 1000 SK, H-801, RC-1500, H-185, EX-1800, R-994, RH-120C, H-241, Marion 3560, H-285, EX-3500, H-485, RH-300. The following parameters are compared: mass, price, digging range, digging power, productivity, motors, travelling speed, availability coefficient, pressure in the hydraulic systems, control systems. The following elements are discussed: schemes of hydraulic drives, main motors and engines, pump stations, hydraulic equipment, hydraulic accumulators, systems for cleaning and cooling hydraulic fluids, control systems, working fluids. Reliability of hydraulic power shovels and factors that influence reliability are analyzed. 54 refs.
Various main circuit equipment with large capacity GTO thyristors are outlined for AC and DC electric cars. The configuration of a PWM converter system is presented for the AC main motor drive system of the Shinkansen trains, and its following features are described: the high power factor control capable of keeping a power factor 100% constantly, energy saving by power regenerative braking, the small triple structure with large capacity reverse-conducting GTO thyristors of 4,500V/3,000A, and the reduction of equivalent interfering current and harmonic current by three phase-triple phase difference operation. Furthermore, a control logic equipment with 16 bit MPU and a main transformer are outlined, and the verification test results of the control logic equipment by an analog model simulation and the combinational test results of the commercial equipment are reported. Prototype VVVF inverter system for DC electric cars is also presented. 6 refs., 13 figs., 3 tabs.
The major details of the inspection and replacement of the bearing journals on each of the four heat transport pumps (HTPs) at Wolsung nuclear generating station in Korea are presented in this paper. Investigation following fracture of one of the journals in 1985 revealed that it was excessively hard. The journal material (ASTM A296 CA 40) is considered to be prone to stress corrosion fatigue if the hardness exceeds Rc 40. In 1986 May, during a planned outage, the HTPs were disassembled, the journals were inspected, found to be excessively hard, and all were replaced. At the same time, the pump to motor couplings were all refurbished to ensure proper alignment.
This paper deal with the research and develop (R and D) on Control Rod Magnetic Suspension Drive Mechanism (MSDM) of CARR. The MSDM is made up of tube, coil, armature, step motor, lead screw etc. The MSDM use electromagnetics as its main principle. The open solenoid electromagnet technique is employed to implement suspension function. It has advantages of high drive precision, high safety feature, good running reliability, easy maintenance and good economical property. The R and D process of MSDM has three phases including single coil electromagnet, principle prototype and engineering prototype. (author)
ABB has developed an electric drive system featuring a high-energy, sodium-sulphur battery. The energy-to-weight ratio of this battery is four times that achieved with conventional lead-acid batteries. To recharge the battery, a charger mounted next to the motor has only to be connected to a household power socket. Road testing of electric cars is already under way, with production of commercially significant series planned for the early 1990s. The drive system will enable a typical family saloon to be driven at 120 km/h and allow a range of action of 200 km in urban traffic. (authors).
The contribution under consideration spans a wide curve from the first deadly accident of motorized aviation in the year 1908 up to newer tendencies of the so-called team resources management on observation points and control stations in order to pursue fundamental questions in man-machine systems. A continuous differentiation in the consideration of the factor human beings in complex technical systems is described. This is illustrated by the example of concepts for leadership, communication and decision making on observation points and control stations.
Spinal cord stimulation (SCS) is frequently used for relief of chronic benign pain resistant to conservative therapies. Clinical practice suggests, at least in patients with failed back surgery syndrome (FBSS), the possibility that SCS significantly improves motor performances. We present here the case of a 41-years-old female patient with FBSS, who showed a clear improvement in muscle strength after SCS, persisting at 6-months follow-up. We speculate that the electrical stimulation of posterior columns could potentiate the caudal, segmental spinal reflexes resulting in a facilitation of motoneurons activation. PMID:16175150
This article deals with the need for control strategies and control systems in buildings with hybrid ventilation. In this respect, control strategies are methods of keeping certain parameters like temperature, air quality etc within specified limits. A control system is automatic and includes sensors, motors, dampers etc. The article also discusses consequences with respect to thermal comfort, air quality and energy use following selection of control parameters for controlling air masses.
This work demonstrate the gasoline volatility influence, at T 10%, T 50% and T 90% distillation points, on the dynamic performance of Otto cycle engines equipped with fuel sequential electronic injection system, by using test standard procedures in dynamometer. For each distillation points three value ranges were established, giving the rise of 27 different gasoline mixtures. The effects of variation in each point on consumption, power and acceleration were verified.
This paper reports several design options for improved passive circulation flow investigated for use in small, modular liquid metal cooled reactors (LMRs). The purpose is to enhance the transition to natural convection cooling following loss of forced circulation flow, reducing thermal transients experienced by the fuel and possibly eliminating the need for emergency pony-motor flow. Design details to minimize pressure drops may also enhance maximum equilibrium power levels possible under natural circulation only.
Several design options for improved passive circulation flow have been investigated for use in small, modular liquid metal cooled reactors (LMRs). The purpose is to enhance the transition to natural convection cooling following loss of forced circulation flow, reducing thermal transients experienced by the fuel and possibly eliminating the need for emergency pony-motor flow. Design details to minimize pressure drops may also enhance maximum equilibrium power levels possible under natural circulation only.
Studies dialysis kinetics of zinc dialkyldithiophosphates, detergent-dispersing agents, alkyl-phenols and base oils. It was established that diffusion kinetics of oil hydrocarbons through membrane of individual compounds and narrow fractions is described by Brinzinger's formula, which is identical to the kinetic reaction formula of the 1st order. It was shown that dialysis can be utilized to determine the content of the ''active substance'' only in sulphonate and alkylsalycilate additives. Increasing temperature from 20 to 40/sup 0/ results in an increased dialysis constant for all studied products by 1.4-1.9 times.
Remote-controlled handling systems are required for work to be done in the decommissioning and dismantling of nuclear facilities. These systems are equipped with electronic devices suitable for use in working environments affected by ionizing radiation. The publication explains the step-wise progress achieved for improving the radiation resistance of electronic devices with the example of a four-quadrant controlling device for the motors of a manipulator. The radiation resistance of the device could be enhanced to radiation energies of 5.500 Gy. This means that a manipulator vehicle equipped with this controlling device can take up to approx. 15 kGy all in all, taking into account its own shielding properties. (DG).
Malfunctions in machinery are often sources of reduced productivity and increased maintenance costs in various industrial applications. For this reason, machine condition monitoring is being pursued to recognise incipient faults. In this paper, the fault diagnostic problem is tackled within a neuro-fuzzy approach to pattern classification. Besides the primary purpose of a high rate of correct classification, the proposed neuro-fuzzy approach also aims at obtaining an easily interpretable classification model. The efficiency of the approach is verified with respect to a literature problem and then applied to a case of motor bearing fault classification.
An Eulerian/Langrangian model was developed to study the two-phase flow in a two-dimensional, axisymmetric, direct-injection diesel engine, under motored and firing conditions. The liquid phase was tracked in a Lagrangian sense using discrete droplet packets (DDP). The gaseous phase was solved using an implicit, iterative, finite-difference, scheme of the control volume variety. Gaseous-phase turbulence was modeled using a compressible two-equation k/epsilon model. Turbulence effects on the liquid phase were modeled by superimposing a randomly oriented turbulent eddy velocity proportional to the root of the turbulent kinetic energy, on each packet's mean relative velocity. Droplet-droplet interactions were neglected. The general knowledge obtained during validation studies, was used to simulate the direct-injection two-stroke diesel engine under motored conditions. The simulation showed that by beginning of the injection, (15/sup 0/ ...
An increased compendium of drugs useful in ocular motor system dysfunction has expanded our capacity to treat selected ocular motility disorders. Adjunctive therapeutic modes (e.g., Fresnel prisms and orthoptic exercises) can also be beneficial. PAN and see-saw nystagmus can be treated with baclofen. Downbeat nystagmus may respond to clonazepam therapy, and prisms may help if the nystagmus can be modified with convergence. Congenital nystagmus may respond minimally to drugs (e.g., baclofen), but prisms or surgical procedures, or both, are still the primary treatment modalities. Innovar may be helpful in patients with severe, incapacitating vestibular disorders, and scopolamine alone or in combination with promethazine may be beneficial in patients with milder ambulatory acute peripheral vestibular disorders. Benign positional vertigo is best treated initially with positional exercises before drug therapy is instituted. Opsoclonus and ocular flutter have been ...
The cost of liquid fuels from coal is a complex function of many factors, such as capital investment, cost of coal and labor cost. Furthermore, the cost will depend on geographical position, the size of the operation and the efficiency of the process. There is no single answer and case studies will have to be made to establish economics at different locations. In the following, the 1980 order-of-magnitude investment costs and operating costs for a coal liquefaction plant are estimated. For a Sasol II type of plant with the product output indicated earlier, the total capital cost is estimated at $4 billion in 1980 dollars. Capital cost accounts for approximately 50%, utilities and materials for 30%, and labor for 20% of the total cost. Given the market value of by-product ethylene ($175/t), tar products ($300/t), chemicals ($300/t), ammonia ($200/t) and sulfur ($25/t), the credit for by-products is $146 million per year. The cost of motor fuel is thus estimated at ...
NuEra Oilfield Services Inc. combines various technologies, including advanced bearing assemblies and compact wireless decoders that interface with downhole directional tools, to engineer unique, purpose-built measurement-while-drilling (MWD) tool string packages. The 9-metre-long MWD tool string is lowered into the drill pipe from the surface. The directional module monitors the position of the drill bit, which the driller can monitor using an electronic drilling recorder at the surface. The directional drillstring uses a mud motor with adjustable bent housing to correct the direction of the well, as the system cannot steer while drilling. At bottomhole, mud circulation continues after the rotation of the drillstring has been stopped, driving the mud motor, which in turn drives the drill bit, permitting a new direction to be taken even though the drillstring is not turning. The operator points the bent housing in a new direction and slides the ...
Gas hydrates are crystalline substances composed of water and gas, in which a solid-water-lattice accommodates gas molecules in a cage-like structure. Gas hydrates are globally widespread in permafrost regions and beneath the sea in sediment of outer continental margins. While methane, propane, and other gases can be included in the clathrate structure, methane hydrates appear to be the most common in nature. The amount of methane sequestered in gas hydrates is probably enormous, but estimates are speculative and range over three orders of magnitude from about 100,000 to 270,000,000 trillion cubic feet. The amount of gas in the hydrate reservoirs of the world greedy exceeds the volume of known conventional gas reserves. Gas hydrates also represent a significant drilling and production hazard. A fundamental question linking gas hydrate resource and hazard issues is: What is the volume of gas hydrates and included gas within a given gas hydrate occurrence Most ...
Gas hydrates are crystalline substances composed of water and gas, in which a solid-water-lattice accommodates gas molecules in a cage-like structure. Gas hydrates are globally widespread in permafrost regions and beneath the sea in sediment of outer continental margins. While methane, propane, and other gases can be included in the clathrate structure, methane hydrates appear to be the most common in nature. The amount of methane sequestered in gas hydrates is probably enormous, but estimates are speculative and range over three orders of magnitude from about 100,000 to 270,000,000 trillion cubic feet. The amount of gas in the hydrate reservoirs of the world greedy exceeds the volume of known conventional gas reserves. Gas hydrates also represent a significant drilling and production hazard. A fundamental question linking gas hydrate resource and hazard issues is: What is the volume of gas hydrates and included gas within a given gas hydrate occurrence? Most ...
There are two types of ionization chamber using magnetically levitated electrode: one is that by Tanaka et al. and the other, by authors'. The latter lacks the sensitivity relative to the former and thereby to solve the problem, authors made an improvement so that the electrode charge could be readout by noncontact after the leviated electrode was electrified by noncontact for an interval. This new type ionization chamber made it possible to measure the quite low dose radiation with stability and high sensitivity. Actually, the electrode was suspended by the teflon thread fixed on the steel cup levitated magnetically in the ionization chamber of which wall was covered by Al and equipped with an electrostatic charger for the electrode by noncontact. After measurement, the electrode was moved in the Faraday cage placed under the chamber to readout the voltage. For operation conditions of the apparatus, observation was done on the relationship between ...
The entrapment of proteins using the sol-gel route provides a means to retain its native properties and artificially reproduce the molecular crowding and confinement experienced by proteins in the cell allowing investigation of the physico-chemical and structural properties of biomolecules at the biotic/abiotic interface. The biomolecules are spatially separated and 'caged' in the gel structure but solutes can freely permeate the matrix. Thus, properties such as the folding of ensembles of individual molecules can be examined in the absence of aggregation effects that can occur in solution studies. Green fluorescent protein from Aequorea coerulescens was used as a model protein to examine the unfolding/re-folding properties of protein in silica gels. The recombinant protein was isolated and purified from Escherichia coli extracts by cell lysis, three-phase partitioning, dialysis, and anion exchange chromatography. The purity of the protein was ...
Testosterone has bipotential effects on male fitness; that is, it both suppresses immune function and maintains characteristics important for reproductive success. Presumably, these effects of testosterone may be more pronounced among polygynous species because testosterone concentrations are generally higher among polygynous than monogamous males. The present study examined sex and species differences in cell-mediated immunity among four arvicoline rodents. The role of mating system and sex steroids in sex differences in immune function was examined in individually housed polygynous meadow (Microtus pennsylvanicus) and montane (M. montanus) voles and monogamous prairie (M. ochrogaster) and pine (M. pinetorum) voles in Experiment 1. No sex differences in splenocyte proliferation were observed among the four species and circulating testosterone concentrations did not correlate with immune function of individuals within each species. The contribution of social isolation to these results ...
The purpose of this study was to correlate MR imaging findings with pathology in experimental hyperoxia-induced acute lung injury, which has similar pathology to diffuse alveolar damage (DAD). Seventeen Yorkshire pigs were studied. These animals were exposed to more than 80% oxygen for 24, 48, 72, and 96 hours in a sealed cage. The lungs were removed and inflated with air infused through the trachea, and then examined by both MRI and high-resolution CT (HRCT). T1-weighted spin-echo (T1WSE), T2-weighted fast (T2WFSE), and half-Fourier acquisition single-shot turbo spin-echo (HASTE) sequences were performed. Severity in MR findings and signal-to-noise ratios (SNR) on MR images were well correlated with pathological scores. CT values were also correlated well with pathologic scores. Abnormal SNR values were obtained from a pathological score of 5, whereas abnormal CT values were obtained from a pathological score of 15. Furthermore, significant differences in SNR were ...
A transplant experiment was conducted to determine whether standard metabolic rate (SMR) of a freshwater shrimp (Palaeomonetes paludosus) would be affected by exposure to trace element-enriched coal combustion waste (coal ash). Shrimp were transplanted into replicate cages in a coal ash-polluted site and a reference site for 8 months. The coal ash-polluted site was characterized by elevated sediment concentrations of As, Cd, Cr, Cu, Ni, Pb and Se compared to sediments in the reference site. After 8 months in the study sites, shrimp in the polluted site appeared to have accumulated As, Cd and Se from the habitat, but there were on differences in survival between the study sites. However, mean SMR of shrimp (measured as O{sub 2} consumption at rest) held in the polluted site was 51% higher than mean SMR of shrimp held in the reference site. The elevation in SMR indicates that the energetic costs of maintenance are greater for shrimp chronically exposed to the ...
Feasibility of using combined release of sterile males and sterile females for population suppression of Earias vittella (Fabricius) was evaluated on okra in two ways. In one study, a combined release of sterile males and sterile females was evaluated under simulated conditions in laboratory, a 10: 10: 1: 1 (sterile male: sterile female: normal female: normal male) ratio effected > 99% sterility. In the second study, in a field cage experiment, a combined release of sterile males and sterile females was evaluated using normal males and tethered normal females. In this experiment, the release of sterile males and sterile females in 10: 10: 1: 1 ratio caused complete 'shut off' of mating of normal females for first 2 days and indicated>93% reduction in the larval progeny in the next generation. The tethered females were allowed to mate only once. E. vittella females mate multiply and so with overwhelming numbers of sterile males present, most probably the next ...
ATR-X (alpha-thalassemia/mental retardation, X-linked) syndrome is a human congenital disorder that causes severe intellectual disabilities. Mutations in the ATRX gene, which encodes an ATP-dependent chromatin-remodeler, are responsible for the syndrome. Approximately 50% of the missense mutations in affected persons are clustered in a cysteine-rich domain termed ADD (ATRX-DNMT3-DNMT3L, ADD{sub ATRX}), whose function has remained elusive. Here we identify ADD{sub ATRX} as a previously unknown histone H3-binding module, whose binding is promoted by lysine 9 trimethylation (H3K9me3) but inhibited by lysine 4 trimethylation (H3K4me3). The cocrystal structure of ADD{sub ATRX} bound to H3{sub 1-15}K9me3 peptide reveals an atypical composite H3K9me3-binding pocket, which is distinct from the conventional trimethyllysine-binding aromatic cage. Notably, H3K9me3-pocket mutants and ATR-X syndrome mutants are defective in both H3K9me3 binding and localization at ...
The possibility of the group preconcentration of Zr(4), Hf(4), Nb(5), and Ta(5) countercurrent liquid chromatography using extraction systems based on di-2-ethylhexylphosphoric acid N-benzoyl-N-phenylhydroxylamine, and tetraoctylethylenediamine (TOEDA) is studied. A method have been proposed for the group extraction of Zr(4), Hf(4), Nb(5), and Ta(5) from solution of geological samples. At the stage of the preconcentration of Zr(40, Hf(4), Nb(5) and Ta(5) with a 0.1 M solution of TOEDA in chloroform from mixture of oxalic (0.01 M) and hydrochloric (0.1 M) acids, matrix components are eluted with a flow of the mobile phase, Then, upon changing the eluent (2.0 M HCl), the four elements mentioned above are extracted to a small (7-8 mL) eluate fraction. The results of determining Zr, Hf, Nb, and Ta by inductively coupled plasma atomic emission spectrometry in the international standard reference material Granite GM after their preconcentration in the system with TOEDA ...
The crystallization of calcium sulfate from aqueous solutions with NaCl is both geological and industrial interest because NaCl is the dominant solute in natural brines and many industrial fluids. Induction periods for the nucleation of calcium sulfate dihydrate were experimentally determined as a function of supersaturation in NaCl solutions from 0 to 6 m at 25 C and in 3.0-m NaCl solutions at temperatures from 25 to 90 C. Using classic nucleation theory, the interfacial tension between gypsum and 3.0-m NaCl solution was estimated to be about 39 mJ/m[sup 2] at 25 C and increases with increasing temperature (to 63 mJ/m[sup 2] at 90 C). It was observed that the induction period decreases with increasing NaCl concentrations up to 3 m and then starts to increase slightly at a given temperature and saturation state. The electrolyte effect on nucleation was proportional to the enhanced solubility of calcium sulfate dihydrate in NaCl solutions. This ...
Nitrogen ion implantation improves the wear resistance of Ti-6Al-4V alloys by forming a hard TiN superficial passivation layer. However, the thickness of the layer formed by traditional ion implantation is typically 100-200 nm and may not be adequate for many industrial applications. We propose to use radio-frequency (RF) plasma nitriding and nitrogen plasma immersion ion implantation (PIII) to increase the layer thickness. By using a newly designed inductively coupled RF plasma source and applying a series of negative high voltage pulses to the Ti-6Al-4V samples. RF plasma nitriding and nitrogen PIII can be achieved. Our process yields a substantially thicker modified layer exhibiting more superior wear resistance characteristics, as demonstrated by data from micro-hardness testing, pin-on-disc wear testing, scanning electron microscopy (SEM), as well as Auger electron spectroscopy (AES). The performance of our newly developed inductively ...
Nitrogen ion implantation improves the wear resistance of Ti-6Al-4V alloys by forming a hard TiN superficial passivation layer. However, the thickness of the layer formed by traditional ion implantation is typically 100-200 nm and may not be adequate for many industrial applications. We propose to use radio-frequency (RF) plasma nitriding and nitrogen plasma immersion ion implantation (PIII) to increase the layer thickness. By using a newly designed inductively coupled RF plasma source and applying a series of negative high voltage pulses to the Ti-6Al-4V samples. RF plasma nitriding and nitrogen PIII can be achieved. Our process yields a substantially thicker modified layer exhibiting more superior wear resistance characteristics, as demonstrated by data from micro-hardness testing, pin-on-disc wear testing, scanning electron microscopy (SEM), as well as Auger electron spectroscopy (AES). The performance of our newly developed inductively ...
Samples of air-dust-concentration- and air-dust-deposit measurements were digested by a standardized wet digestion procedure and the amounts of substances in the dust according to class I TA Luft by Atomic Emission Spectroscopy with Inductively Coupled Plasma (AES-ICP). The characteristic values for procedures according to VDI 2449, sheet 1, were determined for lead, vanadium, cadmium, chromium, copper, nickel and zinc. By partial automatic control of the digestion procedure the personel expenditure of work could be reduced by a factor 13. Dust filter samples were analysed without sample preparation by evaporating the material with a solid state laser. The absolute detection limit was between 1 and 100 ng/cm"2 for the elements arsenic, cadmium, cobalt, chromium, mercury, antimony, selen and thallium. For sampling by means of the Beta-Staubmeter the relative detection limits for the laser-ICP were 10-fold lower than by use of a nebulizer. (orig.).
Homogeneous mixtures of Ce0.8Gd0.2O1.9 (GDC) and La0.6Sr0.4Co0.2Fe0.8O3 (LSCF) nanopowders were successfully synthesized using induction plasma by axial injection of a solution. The resulting nanocomposite powders consisted of two kinds of nanopowders with different mass ratio of GDC/LSCF, such as 3/7 and 6/4. The morphological features, crystallinity, and the phases of the synthesized powders were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), local energy-dispersive x-ray spectroscopy (EDS) analysis, and x-ray diffraction (XRD). The nanopowders are almost globular in shape with a diameter smaller than 100?nm and their BET specific areas are around 20?m2?g?1. The GDC and LSCF phases are well distributed in the nanopowders. In addition, suspens...
Dose measurements were performed in several body regions of patients suffering from inflammatory degenerative diseases (humeral epicondylitis, humeroscapular periarthritis, gonarthrosis, axillary hidradenitis, rheumatoid arthritis, coxarthrosis, parotitis). The problem of the radiation induction of neoplasms is predominant concerning somatic as well as genetic risk, discussed by example of the most frequently occurring organ cancer. Compared to the rate of breast cancer in the highly developed industrial states (5,000 to 6,000 cancers/100,000 women) the 'radiation induction' calculated according to a mathematical model of ICRP 26 (1.25 cases of death for breast cancers/100,000 women following for example irradiation of epicondylitis) is behind several powers of ten and not demonstrable. The genetic radiation exposure is also low. Derived from the measurements it is wrong to give up reliable and approved indications of radiotherapy of ...
Recently there has been much concern with the ability of plants to uptake heavy metals from their surroundings. With the development of instrumental techniques with low detection limits such as inductively coupled plasma-mass spectrometry (ICP-MS), attention is shifting toward achieving faster and more elegant ways of oxidizing the organic material inherent in environmental samples. Closed-vessel microwave dissolution was compared with conventional methods for the determination of concentrations of cerium, samarium, europium, terbium, uranium and thorium in a series of samples from the National Institute of Standards and Technology and from fields in Idaho. The ICP-MS technique exhibited detection limits in parts-per-trillion and linear calibration plots over three orders of magnitude for the elements under study. The results obtained by using nitric acid and hydrogen peroxide in a microwave digestion system for the analysis of reference materials showed close ...
Rhodopseudomonas viridis was grown in liquid culture at 30 degrees C anaerobically in light (generation time, 13 h) and under microaerophilic growth conditions in the dark (generation time, 24 h). The bacterium could be cloned at the same temperature anaerobically in light (1 week) and aerobically in the dark (3 to 4 weeks) if oxygen was limited to 0.1%. Oxygen could not be replaced by dimethyl sulfoxide, potassium nitrate, or sodium nitrite as a terminal electron acceptor. No growth was observed anaerobically in darkness or in the light when air was present. A variety of additional carbon sources were used to supplement the standard succinate medium, but enhanced stationary-phase cell density was observed only with glucose. Conditions for induction of the photosynthetic reaction center upon the change from microaerophilic to phototrophic growth conditions were investigated and optimized for a mutant functionally defective in phototrophic growth. R. viridis ...
Chromium electroplated AISI 316L stainless steel was nitrided using inductively coupled plasma (ICP) for application in the bipolar plate of a polymer electrolyte membrane fuel cell (PEMFC). A continuous and thin chromium nitride layer was formed at the surface of the samples after ICP nitriding for 2 h at 400 C. The interfacial contact resistance (ICR) and corrosion resistance in simulated PEMFC operating conditions were higher than the required values, while they varied with the applied dc bias voltage during the nitriding process. The ICR value decreased with an increase in bias voltage. Potentiodynamic polarization measurements showed that all of the nitrided samples had excellent corrosion resistance with a current density of {proportional_to}10{sup -7} A cm{sup -2} at the cathode. It was also found that the oxygen content at the surface was not increased after the corrosion test. X-ray diffractometry (XRD), field emission scanning electron microscopy ...
The production of cellulolytic enzymes from fungi has been extensively studied. Several mutants of Trichoderma reesei were selected. Most of the studies were carried out on T. reesei, T. viride, T. harzianum, Penicillium funiculosum, Altemaria alternata. Aspergillus phoenicis, A. ustus, A. tamarii, A. japonicus, and A. niger. T. koningii is one of the most active producers of the so-called C, factor, which is indispensable for the rapid and extensive attack on crystal-line cellulose. However, Trichodenna is known to excrete only small amounts of {beta}-glucosidase. Therefore, Trichoderma is supplemented with {beta}-glucosidase from Aspergillus to increase the saccharification rate of cellulose to glucose as the main sugar. Induction of mutations in Trichodenna spp. rather than T. viride as a tool for the enhancement of {beta}-glucosidase activity was reported. Unfortunately, T. reesei is a poor producer of {beta}-glucosidase. On the other hand, T. harzianum M{sub ...
Cell death in general can be a physiological process of cell number regulation in tissue, or it can be the result of exo or endogenous injuries, such a low-dose of radiation. Chicken B cell population in the bursa of Fabricius are very susceptible to PCD. Our present studies concern the development of radiation damage of chicken defence mechanisms. In 6 experiments pathogen free chicken were irradiated by gamma rays with the total doses of 0.25, 0.5, 1.0, 2.0 and 4.0 Gy. The induction of apoptosis was checked by Flow-cyto-meter 12 h after irradiation in bursa cell suspension. There is some increase in the number of induced apoptotic cells 12 h after irradiation at the dose 0.5-.4.0 Gy. There were no significant changes in the proportion of proliferating lymphocytes (G2 M), but cellularity decreased significantly at dose 2.0 and 4.0 Gy/12 h after irradiation. (author)
Protocols were standardized for in vitro propagation of several elite and diverse banana accessions using shoot tip explants. Tissue culture raised plants were field planted at multiple locations. Studies were undertaken for the induction of mutations using multiple shoot cultures of six selected cultivars, Shreemanti (AAA), Basrai (AAA), Lal Kela (AAA), Rasthali (AAB), Karibale Monthan (ABB) and a wild diploid (BB). These shoot cultures were irradiated at different doses of gamma rays (0-100 Gy) and subcultured thrice (up to M_1V_3) to separate shimeras, followed by induction of rooting (M_1V_4). In general, the rate of multiplication had a negative association with the dose of gamma rays. Enhanced multiplication of shoots was noticed at lower doses. The proliferation of shoots was arrested beyond 50 Gy and a dose of 70 Gy was completely lethal for all the genotypes studied. The rooted plantlets were hardened in the green house and in the ...
The NRL Long Pulse Induction Linac is being employed in a Free Electron Laser (FEL) experiment. The authors present results of beam transport and focusing experiments as well as measurements of the output radiation generated by various magnetic wigglers. The electron gun of the accelerator presently has a 17-cmdiam. cold cathode which is located in a nearly zero magnetic field (B /SUB z/ less than or equal to 5 G). The gun voltage is flat to within approx. = + or - 5% for 1.5 #mu#sec with this graphite brush cathode. The beam is focused by a series of solenoidal coils as it propagates through the 4-m-long accelerator."2 A solenoidal field which can be varied from 1-10 kG confines the beam in the FEL interaction region. Previous experiments were limited by poor beam transport, focusing, and matching into the relatively large solenoidal field in the FEL region. By smoothing the axial magnetic field profile in the accelerator and making a more adiabatic transition ...
Along with the shrinkage of LSI geometries, a higher quality of ultrapure water has been continuously required. Analytical technology for ultrapure water has also progressed before ultrapure water production technology improvements. In this study, we performed optimization of the analytical conditions for the direct analysis of acid droplets, and established an analytical technology for measurements of trace amounts of metallic impurities deposited on a wafer surface by means of Vapor Phase Decomposition (VPD)/Inductively Coupled Plasma Mass Spectrometry (ICP-MS). As a result, analytical technology for metallic elements of the 1x10"8 atoms/cm"2 level on wafer surface has been established. By applying analytical technology to the wafer that has been contacted with ultrapure water, a new evaluation technology for ultrapure water quality by means of wafer surface contamination has been established. We confirmed good correlations between metal contamination of the ...
Inductively coupled fluorocarbon (CF4/Ar and C4F8/Ar) plasmas were used to etch HfO2, which is a promising high-dielectric-constant material for the gate of complementary metal-oxide-semiconductor devices. The etch rates of HfO2 in CF4/Ar plasmas exceeded those in C4F8/Ar plasmas. The tendency for etch rates to become higher in fluorine-rich (high F/C ratio) conditions indicates that HfO2 can be chemically etched by fluorine-containing species. In C4F8/Ar plasmas with a high Ar dilution ratio, the etch rate of HfO2 increased with increasing bias power. The etch rate of Si, however, decreasd with bias power, suggesting that the deposition of carbon-containing species increased with increasing the power and inhibited the etching of Si. The HfO2/Si selectivity monotonically increased with increasing power, then became more than 5 at the highest tested bias power. The carbon-containing species to inhibit etching of Si play an important role in enhancing the HfO2/Si ...
Background: The effective-dose method which was proposed by the ICRP (International Commission of Radiation Protection) for the estimation of risk to the general population from occupational or environmental, low-dose radiation exposure is not adequate for estimating the risk of cancer induction by radiotherapy of malignant or nonmalignant diseases. Methods:The risk of cancer induction by radiotherapy of benign diseases should be based on epidemiologic data directly derived from follow-up studies of patients who had been given radiotherapy for nonmalignant diseases in the past. Results: Risk factors were derived from epidemiologic studies of patients treated with irradiation for nonmalignant diseases to be used for selecting treatment options and optimizing treatment procedures. Conclusion: In most cases, cancer risks estimated by the effective-dose method may overestimate the true risks by one order of magnitude, yet in other cases even may ...
Background: The effective-dose method which was proposed by the ICRP (International Commission of Radiation Protection) for the estimation of risk to the general population from occupational or environmental, low-dose radiation exposure is not adequate for estimating the risk of cancer induction by radiotherapy of malignant or nonmalignant diseases. Methods:The risk of cancer induction by radiotherapy of benign diseases should be based on epidemiologic data directly derived from follow-up studies of patients who had been given radiotherapy for nonmalignant diseases in the past. Results: Risk factors were derived from epidemiologic studies of patients treated with irradiation for nonmalignant diseases to be used for selecting treatment options and optimizing treatment procedures. Conclusion: In most cases, cancer risks estimated by the effective-dose method may overestimate the true risks by one order of magnitude, yet in other cases even may ...
Elise is a heavy ion induction linear accelerator that will demonstrate beam manipulations required in a driver for inertial fusion energy. With a line charge density similar to that of heavy ion drivers, Elise will accelerate a #>=# 1 gs beam pulse of K"+ ions from an initial energy of 2 MeV to a final energy #>=# 5 MeV. In the present design, the Elise electrostatic quadrupoles (ESQ) will have a 2.33 cm radius aperture operating at #+-#59 kV. The half-lattice periods range from 21 cm to 31 cm. The entire machine will be approximately 30 m long, half of that is the induction accelerator and the remaining half is the injector (including the Marx generator) and the matching section. Elise will be built in a way that allows future expansion into the full ILSE configuration, therefore it will have an array of four ESQ focusing channels capable of transporting up to a total of 3.2 A of beam current. Elise will also have an active alignment ...
In this work, the silicon oxynitride layer was studied as a tunneling layer for non-volatile memory application by fabricating low temperature polysilicon thin film transistors on glass. Silicon wafers were oxynitrided by only nitrous oxide plasma under different radio frequency powers and plasma treatment times. Plasma oxynitridation was performed in RF plasma using inductively coupled plasma chemical vapor deposition. The X-ray energy dispersive spectroscopy was employed to analyze the atomic concentration ratio of nitrogen/oxygen in oxynitride layer. The oxynitrided layer formed under radio frequency power of 150 W and substrate temperature of 623 K was found to contain the atomic concentration ratio of nitrogen/oxygen as high as 1.57. The advantage of high nitrogen concentration in silicon oxide layer formed by using nitrous oxide plasma was investigated by capacitance-voltage measurement. The analysis of capacitance-voltage characteristics demonstrated that ...
In this work, the silicon oxynitride layer was studied as a tunneling layer for non-volatile memory application by fabricating low temperature polysilicon thin film transistors on glass. Silicon wafers were oxynitrided by only nitrous oxide plasma under different radio frequency powers and plasma treatment times. Plasma oxynitridation was performed in RF plasma using inductively coupled plasma chemical vapor deposition. The X-ray energy dispersive spectroscopy was employed to analyze the atomic concentration ratio of nitrogen/oxygen in oxynitride layer. The oxynitrided layer formed under radio frequency power of 150 W and substrate temperature of 623 K was found to contain the atomic concentration ratio of nitrogen/oxygen as high as 1.57. The advantage of high nitrogen concentration in silicon oxide layer formed by using nitrous oxide plasma was investigated by capacitance-voltage measurement. The analysis of capacitance-voltage characteristics demonstrated that ...
The CYP1A (EROD)-inducing potencies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 3,3minutes or feet,4,4minutes or feet,5-pentachlorobiphenyl (PCB126) and benzo(k)fluoranthene (B(k)F) were studied in avian embryo livers. TCDD and PCB126 proved to be much more potent as inducers in the chicken than in the other species examined. This finding is consistent with a considerably higher sensitivity of the chicken compared with a number of other avian species to the embryotoxic effects of these compounds. Furthermore, the relative potencies of the tested Ah receptor agonists as CYP1A inducers differed substantially between species. B(k)F and PCB126 showed similar induction potencies in domestic duck embryos, whereas PCB126 is much more potent than B(k)F in the chicken. Also, the potency of PCB126,relative to that of TCDD, was much lower in quail embryo liver in vitro than in chicken embryo liver. Thus, there are large interspecific differences in birds in the sensitivity ...
To identify radio-protective agent candidate among medicinal plants and to elucidate the mechanism of action of the candidate material by using modern biochemical and molecular biological methods, we screened radio-protective activity among 48 medicinal plants. Seven samples showed above 20% protective activities against oxidative cell damage: Euryale ferox, Glycyrrhiza uralensis, Salvia miltiorrhiza, Eucomia ulmoides, Paeonia suffruticosa, Spirodela polyrrhiza, and Nelumbo nucifera. We also screened for oxidative stress sensitizing activity among other 51 medicinal plants. Among those samples, 11 samples showed good sensitizing effect; Melia azedarach, Agastache rugosa, Catalpa ovata, Prunus persica, Sinomenium acutum, Pulsatilla koreana, Oldenlandia diffusa, Anthriscus sylvestris, Schizandra chinensis, Gleditsia sinensis, and Cridium officinale. We also reported the radio-protective effect of DTT. The treatment of DTT increased cell survival after gamma-irradiation, decreased in the ...
2-hydroxyethyl methacrylate (HEMA) has been deposited onto the surface of silicon substrate (thickness = 500 ?m) using plasma polymerization technique. Polymerization process was carried out in an in-house developed inductively coupled plasma polymerization setup. The depositions were carried out using RF power supply (13.56 MHz) at power of 75 W for 10 and 40 min. The RF supply was coupled to the inductance through a matching network. The effect of plasma polymerization (surface grafting) on the degree of surface modification has been investigated. The chemical changes on the polymer backbone are followed from the results of Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS), which show the peaks corresponding to the functional groups of the HEMA polymerized onto the silicon surface. The morphology of the modified surfaces has also been investigated using scanning electron microscopy (SEM) and atomic ...
A new method for the determination of {sup 237}Np and Pu isotopes in large soil samples has been developed that provides enhanced uranium removal to facilitate assay by inductively coupled plasma mass spectrometry (ICP-MS). This method allows rapid preconcentration and separation of plutonium and neptunium in large soil samples for the measurement of {sup 237}Np and Pu isotopes by ICP-MS. {sup 238}U can interfere with {sup 239}Pu measurement by ICP-MS as {sup 238}UH{sup +} mass overlap and {sup 237}Np via {sup 238}U peak tailing. The method provides enhanced removal of uranium by separating Pu and Np initially on TEVA Resin, then transferring Pu to DGA resin for additional purification. The decontamination factor for removal of uranium from plutonium for this method is greater than 1 x 10{sup 6}. Alpha spectrometry can also be applied so that the shorter-lived {sup 238}Pu isotope can be measured successfully. {sup 239}Pu, {sup 242}Pu and {sup 237}Np were measured ...
This study develops a framework for analysis and assessment of the cost of ownership and use of major cooking appliances. This involved an assessment of the monetary cost as well as the cost of human resources required to maintain and operate cooking systems. The goal was to provide information useful in making purchase decisions within a framework that can be used to organize information about cost beyond the initial purchase price. Five cooktops - conventional electric oil, induction, solid element with thermostatic control, solid element with thermal limiter, and gas - and a microwave oven were used to develop a decision-making matrix. Results were used to assign weights in the matrix used to develop a 10-point scale that represented the total cost of owning and using a cooking system in food preparation. Based on the matrix, the microwave oven received the highest score followed by gas, conventional electric coil, solid element with thermostatic control, solid ...
Two plasma chemistries, i.e., CH_4/H_2/Ar and Cl_2/Ar, were compared for the etching of InGaP, AlInP, and AlGaP under inductively coupled plasma (ICP) conditions. While the etching with CH_4/H_2/Ar discharges appears to be ion driven, Cl_2/Ar discharges showed an additional strong chemical enhancement. The highest etch rate (#approx#1 #mu#m/min) for InGaP was achieved at high ICP source power (#>=#750 W) with the Cl_2/Ar chemistry. Cl_2/Ar discharges provided very smooth surfaces in all three materials with root-mean-square roughness measured by atomic force microscopy around 2 nm. This result may be due to the efficient ion-assisted product desorption in this chemistry. The etched near-surface region of InGaP (#approx#100 Angstrom) with Cl_2/Ar maintained almost the same stoichiometry as that of the unetched control. By contrast, the CH_4/H_2/Ar plasma chemistry produced somewhat rougher surfaces and depletion of phosphorous (P) from the surface of InGaP. ...
We reported the radio-protective effect of DTT. The treatment of DTT increased cell survival after gamma-irradiation, decreased in the frequencies of micronucleus, and reduction in DNA fragmentation and apoptotic cells. Induction of apoptosis after UV-C irradiation was revealed by the changes in the relative cell death, increase in the relative amount of apoptotic cells, and the induction of DNA fragmentation. About 100 medicinal plants were purchased and methanol extract samples were prepared. Radio-protective and radio-sensitizing activities of these samples were screened. Seven samples showed above 20% radio-protective activities: Salvia miltiorrhiza, Areca catechu, Cornus officinalis, Alpiniae officinari rhizoma, Meliae fructus, Alpiniae katsumadaii semen, Betulae cortex. Acanthopanax sessiliflous showed the highest radio-sensitizing effect and 10 other samples revealed moderate activities: Melia japonica, Agastache rugosa, Platycodon ...
Two series of diffusion tests were performed to examine the degradation of dichloromethane (DCM) as it diffuses through clay. The first series showed the use of a synthetic leachate with no significant initial bacterial population diffusing through a plug of intact clay; there was an induction period of 95--135 d, during which diffusion was as expected in the absence of degradation, followed by a second stage, where degradation occurred with an apparent half-life of less than 55 d at a temperature of 24 C. The second series of tests examined the diffusion of an actual leachate from the Keele Valley Landfill (KVL) (which provided both nutrients and a source of bacteria), through a compacted clay. In these tests, the induction period was reduced to 40--60 d, after which the apparent half-life was 20 d or less at 27 C. The diffusion coefficient for DCM was approximately 8 {times} 10{sup {minus}10} m{sup 2}/s, with partitioning coefficient K{sub d} ...
An electric propulsion concept suitable for delivering heavy payloads from low earth orbit (LEO) to high energy earth orbit is proposed. The system consists of a number of pulsed inductive plasma thrusters powered by a 100 kWe space nuclear power system. The pulsed plasma thruster is a relatively simple electrodeless device. It also exhibits adequate conversion to thrust power in the desired I sub sp regime of 1500 to 3000 seconds for optimal payload transfer from low earth to high earth orbit. Because of these features and the fact that the nuclear power unit will be capable of delivering sustained high power levels throughout the duration of any given mission, the system presented appears to be a very promising propulsion candidate for advanced orbital transfer vehicle (OTV) applications. An OTV, which makes use of this propulsion system and which has been designed to lift a 9000-lb payload into geosynchronous earth orbit, (GEO) is also examined.
A study of stress corrosion cracking susceptibility of Zircaloy-4 in chloride-containing aqueous methanolic media is presented. The influence of water content is investigated in the 5-100 vol. % water range. The dependence of stress corrosion cracking on potential is evidenced. A close correlation is established with pitting susceptibility determined by a statistical analysis of induction times. A correlation with the repassivation potential is observed in the water-rich solutions. In the low water content solutions, two repassivation curves are determined according to the experimental technique. Pit morphology and fractography show a transition from aqueous to organic media. (author).
Recent research work on adjustable speed pumped storage plants conducted in Japan, the USA and Europe suggests that they have many advantages over fixed-speed plants, and can contribute to power system regulation even in pump mode. This paper describes two types of static frequency converter for such pumped storage plants, especially those with greatly fluctuating heads. The design characteristics and operation of the doubly fed induction machine and the synchronous machine with DC link converter are set out and the devices compared. (UK)
Solenoid transport of high current, heavy ion beams is considered for several stages of a heavy ion fusion driver. In general this option is more efficient than magnetic quadrupole transport at sufficiently low kinetic energy and/or large e/m, and for this reason it has been employed in electron induction linacs. Ideally an ion beam would be transported in a state of Brillouin flow, i.e. cold in the transverse plane and spinning at one half the cyclotron frequency. The design of appropriate solenoids and the equilibrium and stability of transported ion beams are discussed. An outline of application to a fusion driver is also presented.
Introduction Gastrointestinal bleeding is a common life-threatening problem, causing significant mortality, costs and resource allocation. Its management requires a dynamic multidisciplinary approach that directs diagnostic and therapeutic priorities appropriately. Materials and methods Articles published within the past 15 years, related to gastrointestinal bleeding, were reviewed through MEDLINE search, in addition to current guidelines and standards. Results Decisions of ICU admission and blood transfusion must be individualized based on the extent of bleeding, hemodynamic profile and comorbidities of the patient and the risk of rebleeding. A secure airway may be required to optimize oxygenation and to prevent aspiration. Doses of induction agents must be reduced due to the changes in v...
We present a study of the interaction between Josephson junctions in circular superconducting rings and non-classical microwaves, treating both quantum mechanically. A Hamiltonian that describes both inductive and capacitive coupling between the two systems is derived within the external field approximation. Other Hamiltonians which go beyond the external field approximation, and describe explicitly the interaction of the quantum circuit that produces the non-classical microwaves with the Josephson junction circuit, are also presented. A comparison between current experiments which use classical electromagnetic fields and the proposed experiments that use non-classical microwaves, is made. (orig.) With 6 figs., 32 refs.
Fifty patients scheduled to undergo IVF received a standard anesthetic of fentanyl and propofol for induction, followed by propofol infusion, with Bispectral index values and modified Ramsey sedation scores recorded at 5-minute intervals for the duration of anesthesia care. Moderate sedation was found only transiently during the first 5-10 minutes of the oocyte retrieval, but thereafter the level of sedation increased, with deep sedation and general anesthesia measured in all patients as determined by both the Bispectral index scores and lack of response to painful stimulation.
Methods are described for the production of callus and subsequent shoot and root induction and multiplication using stamen filaments, nodes of young stems of mature trees or cotyledon petioles. A high frequency of contamination occurred using nodal sections from mature trees, whereas up to 100% sterility was obtained with cotyledons and stamens. The rooting % of shoot cultures from nodes or stamen callus was low compared with that of shoots from seedling callus. Considerable variation was observed between clones from different trees in their ability to produce shoots and roots. 27 references
Purpose: To prevent evaporization stills against corrosion due to radioactive liquid wastes. Constitution: Microwaves are supplied from a microwave generator by way of a wave guide tube and through a microwave permeation window to the inside of an evaporatization still. A matching device is attached to the wave guide tube for transmitting the microwaves in order to match the impedance. When the microwaves are supplied to the inside of the evaporization still, radioactive liquid wastes supplied from a liquid feed port by way of a spray tower to the inside of the evaporization still is heated and evaporated by the induction heating of the microwaves. (Seki, T.).
This review of methods and designs of transducers for nondestructive determination of the magnitude and nature of the anisotropy of magnetic properties (permeability, induction, coercive force, energy loss due to magnetization reversal) in local portions of ferromagnetic sheet and, in some cases, in individual parts of products. The need to measure the anisotropy is considered for two angles: for the case when the anisotropy is due to the crystallographic texture and determines the main operating characteristics of widely used sheet such as electrical steel and automobile body sheet, and for crystallographically isotropic materials, in which the anisotropy of magnetic properties as a result of mechanical stresses is a measure for determining the internal stresses.
Titanium metal-matrix composites (MMC) are prime candidate materials for aerospace applications be-cause of their excellent high-temperature longitudinal strength and stiffness and low density compared with nickel- and steel-base materials. This article examines the steps GE Aircraft Engines (GEAE) has taken to develop an induction plasma deposition (IPD) processing method for the fabrication of Ti6242/SiC MMC material. Information regarding process methodology, microstructures, and mechani-cal properties of consolidated MMC structures will be presented. The work presented was funded under the GE-Aircraft Engine IR & D program.
Studies on pupal irradiation of Earias vittella Fabricius, were undertaken to determine the optimum dose for sterile and competitive adults. Late pupae were irradiated with gamma radiation doses ranging from 150 to 300 Gy. Emerging adults were normal and without malformation. When males that emerged from irradiated pupae were crossed with normal female, fecundity as well as longevity was comparable to control, but there was drastic reduction in percent egg hatch in all the treatments. However, when females emerging from irradiated pupae were crossed with normal male, there was reduction in the fecundity as well as fertility and this effect was dose dependent. (author).
Several compounds were evaluated in nonhuman primates for their potential to induce neoplasms, especially hepatocellular carcinoma (HCC). The compounds can be classified into three groups: food contaminants, model rodent carcinogens, and nitrosamines. All three compounds in the food contaminants group, namely, aflatoxin B1, sterigmatocystin, and methylazoxymethanol acetate, induced HCC. None of the model rodent carcinogens tested consistently induced HCC in rhesus and cynomolgus monkeys. Three of four nitrosamines evaluated induced HCC in rhesus and cynomolgus monkeys. One nitrosamine, diethylnitrosamine, is a predictable and potent inducer of HCC and is useful for establishment of a nonhuman primate model for numerous oncologic studies.
Several fast neutral pressure gauges have been installed on NSTX [National Spherical Torus Experiment] to measure the vessel and divertor pressure during inductive and coaxial helicity injected (CHI) plasma operations. Modified, PDX [Poloidal Divertor Experiment]-type Penning gauges have been installed on the upper and lower divertors. Neutral pressure measurements during plasma operations from these and from two shielded fast Micro ion gauges at different toroidal locations on the vessel mid-plane are described. A new unshielded ion gauge, referred to as the In-vessel Neutral Pressure (INP) gauge is under development.
As a part of the program at the Lawrence Livermore National Laboratory (LLNL) in induction-linac free-electron laser (IFEL) research, the authors are conducting a variety of activities addressing the unique requirements imposed on IFEL wiggler systems. They are actively developing improved DC iron-core electromagnetic wiggler designs to attain higher peak fields, greater tunability, and lower random error levels. They are pursuing specialized control systems, such as magnetic-field and beam-position controllers, which can relax requirements on the wiggler itself. They are also pursuing basic studies to establish the effect of radiation on permanent magnets.
As a part of the program at the Lawrence Livermore National Laboratory (LLNL) in induction-linac free-electron laser (IFEL) research, we are conducting a variety of activities addressing the unique requirements imposed on IFEL wiggler systems. We are actively developing improved dc iron-core electromagnetic wiggler designs to attain higher peak fields, greater tunability, and lower random error levels. We are pursuing specialized control systems, such as magnetic-field and beam-position controllers, which can relax requirements on the wiggler itself. We are also pursuing basic studies to establish the effect of radiation on permanent magnets.
Earlier work carried out on the hydrogen-diesel dual-fuel engine indicates that knock sets in when the inducted hydrogen exceeds about 60% of input energy with a pilot quantity of 30% of full load diesel amount. Some of the findings of an investigation into knock-free performance of a hydrogen-diesel dual-fuel engine with the addition of a diluent-carbon dioxide are presented. The effects of carbon dioxide on the suppression of knocking in the hydrogen-diesel dual-fuel engine and on the improvement in the knock limited power output are described.
Drawing on work in epistemology and the philosophy of science, this paper seeks to provide very general reasons for why a comparative perspective needs to be applied to the inferential procedures of research methodologies where these concern the issue of justifying knowledge claims. In particular, the paper explores the role of culture on a number of important patterns of reasoning that figure in inferential arguments in research methodologies. The patterns examined are induction, both enumerative and analytical, hypothetico-deductive reasoning, and abductive inference. In each case it is argued that substantive theories about the world, including cultures, significantly affect inferential procedures. Examples chosen to illustrate this in more detail mostly reflect the impact of Confucian ...
Isotopic analyses of radioactive materials such as irradiated nuclear fuel are of major importance for the optimization of the nuclear fuel cycle and for safeguard aspects. Among the mass-spectrometric techniques available, inductively coupled plasma mass spectrometry (ICP-MS) and thermal ionization mass spectrometry are the most frequently applied methods for nuclear applications. Because of the low detection limits, the ability to analyze the isotopic composition of the elements and the applicability of the techniques for measuring stable as well as radioactive nuclides with similar sensitivity, both mass-spectrometric techniques are an excellent amendment to classical radioactivity counting methods. The paper describes selected applications of multicollector ICP-MS in combination with c...
Male meadow voles maintained in a long photoperiod (LP) from birth have heavier brains than do females, but in short photoperiods (SP) this sex dimorphism is absent. Testosterone propionate (TP) administration on the second day of postnatal life produced significant increases in brain weight of LP but not SP females at 35 days of age. Short daylengths reduce the responsiveness of the meadow vole nervous system to the masculinizing effects of perinatal testosterone and may, in part, mediate the seasonally reduced sex difference in brain weight. PMID:8446686
A high-power microwave Free Electron Laser (FEL) experiment has been performed to study the inherent electron beam bunching that occurs in the FEL interaction. An induction linac delivered a 1 kA, 2.2 MeV electron beam to a FEL amplifier. In the process of amplifying the input signal of frequency 35 GHz to power levels of the order of 10 MW, the electron beam was bunched by the ponderomotive force. In this paper we describe the FEL experiment and the optical technique that was used to observe the bunches. Their properties as functions of the basic FEL parameters are discussed. copyright 1996 American Institute of Physics.
The mutual inductance between parallel transmission lines influences the locating of the transmission line faults. A fault location algorithm for parallel lines developed in this paper takes into account the magnetic coupling between parallel lines. The paper presents a detailed description of the developed algorithm and test results performed on a simplified real transmission line. The obtained error is less than 0.5 percent in most cases. Also, the developed algorithm is not sensitive to typical fault parameters, such as: resistance, type, location, and incidence angle. 7 refs, 4 figs, 12 tabs
We report the case of a 22-year-old man with Ewing's sarcoma who attained a complete remission (CR) after combination radiotherapy and chemotherapy. Secondary acute lymphoblastic leukemia with multiple cytogenetic abnormalities involving chromosome 5 and 7 developed 16 years later. The patient underwent induction chemotherapy and entered a CR. Peripheral blood stem cell transplantation from a matched sibling was performed successfully and he is in complete remission of both ALL and Ewing's sarcoma. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)
A new simple multi-well plate-based assay to determine monocyte differentiation-inducing activity was developed. It is based on the increase of macrophage adherence after the induction of monocyte differentiation. The assay was conducted using a human monocytic leukemia cell line, THP-1, treated with either 12-O-tetradecanoylphorbol 13-acetate or cytokines, such as tumor necrosis factor-alpha and interferon-gamma. This method is sensitive and easy to perform, especially in case of analyzing a large number of samples. PMID:17920620
A new simple multi-well plate-based assay to determine monocyte differentiation-inducing activity was developed. It is based on the increase of macrophage adherence after the induction of monocyte differentiation. The assay was conducted using a human monocytic leukemia cell line, THP-1, treated with either 12-O-tetradecanoylphorbol 13-acetate or cytokines, such as tumor necrosis factor-? and interferon-?. This method is sensitive and easy to perform, especially in case of analyzing a large number of samples.
The effect of 50 Hz and 60 Hz (frequencies of current distribution) and 20 kHz to 50 kHz (frequencies of induction cooktop) magnetic interference on implanted pacemakers have been assessed with the present generation of device technology. Sixty patients implanted in 1998 and 1999 with dual chamber pacemakers from 9 different manufacturers were monitored with telemetry while passing through, and standing between a system of two coils. They generated a 50 Hz or a 60 Hz magnetic field at 50 microT. Then, patients used a cooktop at different power. The recordings were made with the standard setting of "medically correct" sensing parameters chosen for the patients. Then pacemakers were reprogrammed to the unipolar mode, with the highest atrial (A) and ventricular (V) sensitivity that did not induce muscular inhibition while moving. Between each exposure (50 Hz, 60 Hz or 20 kHz to 50 kHz), the pacemaker programmation was controlled. At the end of the tests, pacemakers ...
High quality single-walled carbon nanotubes (SWNT) have been synthesized at large scales by the method of direct evaporation of carbon black and metallic catalyst mixtures, using induction thermal plasma technology. The processing system consists mainly of an RF plasma torch, which generates a plasma jet of extremely high temperature (?15 000 K), with a high energy density and abundance of reactive species (ions and neutrals). With the present reactor system, it has been demonstrated that carbon soot product which contains approximately 40 wt% of SWNT can be continuously synthesized at the high production rate of ?100 g h-1. The processing parameters involved have been examined closely in order to evaluate their individual influences on SWNT synthesis. The results have shown that the quality and purity of the SWNT produced are critically affected by the grade of carbon black, the plasma gas composition and the metallic catalyst employed. Theoretical calculations, ...
Peroxisome proliferating agents (PPAs) are a structurally diverse group of chemicals that include environmental chemical contaminants such as certain chlorinated herbicides, solvents and plasticizers. PPAs have previously been shown to induce anti-trout laruci acid hydroxylase immunoreactive proteins in bluegill and catfish. In this investigation, induction of lauric acid hydroxylase activity and immunoreactive proteins was confirmed, and the mass spectral analysis of specific hydroxylation products was performed in order to identify possible species-specific differences in fatty acid metabolism. Male bluegill (Lepomis macrochirus) and channel catfish (Ictalurus punctatus) were administered clofibrate or ciprofibrate 48 hr prior to hepatic or trunk kidney (catfish only) microsome preparation. While no significant differences were observed in male catfish, male bluegill had significant decreases in hematocrit and plasma protein indicating hemodilution due to ...
The /sup 13/C-AP breath test is shown to be a convenient, noninvasive method to monitor velocity and capacity of P450-dependent AP N-demethylation in infancy and childhood. According to /sup 13/C-AP breath tests, neonates have a very low capacity to eliminate /sup 13/CO/sub 2/, which is only 15 to 21% of the activity in adults. During the first year of life AP N-demethylation increases to reach its maximum at about 2 years; afterwards a slight decrease occurs. In 25 neonates exposed prenatally to different antiepileptic drugs /sup 13/C-AP breath test was efficiently used to prove that cytochrome AP N-demethylation was considerably stimulated. After primidone/phenobarbitone, especially in combination with phenytoin, /sup 13/C elimination reaches and even surpasses the range for older children. Valproate exposure during fetal life is not consistently followed by a significant increase in AP N-demethylation. The enzyme induction demonstrated by /sup 13/C-AP breath ...
Purpose To investigate the sensitivity and accuracy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for restaging the mediastinum after induction chemotherapy in patients with non-small-cell lung cancer (NSCLC). Patients and Methods One hundred twenty-four consecutive patients with tissue-proven stage IIIA-N2 disease who were treated with induction chemotherapy and who had undergone mediastinal restaging by EBUS-TBNA were reviewed. On the basis of computed tomography, 58 patients were classified as having stable disease and 66 were judged to have had a partial response. All patients subsequently underwent thoracotomy with attempted curative resection and a lymph node dissection regardless of EBUS-TBNA findings. Results Persistent nodal metastases were detected by using EBUS-TBNA in 89 patients (72%). Of the 35 patients in whom no metastases were assessed by EBUS-TBNA, 28 were found to have residual stage IIIA-N2 ...
1-Furan-2-yl-3-pyridin-2-yl-propenone (FPP-3) is an anti-inflammatory agent with a propenone moiety and chemically synthesized recently. In this study, we examined the chemopreventive effect of FPP-3 on 7,12-dimethylbenz[a]anthracene (DMBA)-induced genotoxicity in MCF-7 cells. FPP-3 reduced the formation of the DMBA-DNA adduct. DMBA-induced CYP1A1 and CYP1B1 gene expression and enzyme activity were inhibited by FPP-3. It inhibited DMBA-induced aryl hydrocarbon receptor (AhR) transactivation and DMBA-inducible nuclear localization of the AhR. Induction of detoxifying phase II genes by chemopreventive agents represents a coordinated protective response against oxidative stress and neoplastic effects of carcinogens. Transcription factor NF-E2 related factor 2 (Nrf2) regulates antioxidant response element (ARE) of phase II detoxifying and antioxidant enzymes, such as glutathione S-transferase (GST) and NAD(P)H:quinone oxidoreductase (QR). FPP-3 increased the expression ...
Preterm children born before 32 weeks of gestation represent 1% of the annual births in Switzerland, and are the most at risk of neurodevelopmental disabilities. A neurological surveillance is thus implemented in the neonatal units, and multidisciplinary neurodevelopmental follow-up is offered to all our preterm patients. The follow-up clinics of the University hospitals in Lausanne and Geneva follow the Swiss guidelines for follow-up. An extended history and neurological examination is taken at each appointment, and a standardized test of development is performed. These examinations, which take place between the ages of 3 months and 9 years old, allow the early identification and treatment of developmental disorders frequent in this population, such as motor, cognitive or behavioral disorders, as well as the monitoring of the quality of neonatal care. PMID:21452511
The results of studies performed for the development of a new process of the thermal cracking of tar as a suspension with ground Baltic oil shale in order to obtain motor fuel components are reported. The experimental results suggest undoubted advantages of the process over industrial thermal cracking because the deep degradation of tar (the yields of a gasoline fraction with bp to 180?C, middle distillates with bp of 180?360?C, and feedstock for catalytic cracking with bp of 360?520?C were ~12, 43?44, and ~15?16 wt % on an initial tar basis) was achieved upon the single-stage processing of the raw material under relatively mild conditions (5 MPa, 425?C, and a feed space velocity of 1.0 h?1). The resulting coke-like products and V and Ni contained in the raw material were deposited on the ...
The influence of bowl offset on motored mean flow and turbulence in a direct injection diesel engine has been examined with the aid of a multi-dimensional flow code. Results are presented for three piston geometries. The bowl geometry of each piston was the same, while the offset between the bowl and the cylinder axis was varied from 0.0 to 9.6% of the bore. The swirl ratio at intake valve closing was also varied from 2.60 to 4.27. It was found that the angular momentum of the air at TDC was decreased by less than 8% when the bowl was offset. Nevertheless, the mean (squish and swirl) flows were strongly affected by the offset. In addition, the distribution of turbulent kinetic energy (predicted by the /delta/-e model) was modified. Moderate increases (10% or less) in mass averaged turbulence intensity at TDC with offset were observed.
As in all vehicles of this type, low weight and aerodynamic drag must be achieved without compromising safety, and in an extremely rugged structure. This has been done by using a chrome-molybdenum steel space-frame, surrounded by a Kevlar/foam sandwich body shell. The solar panel wing, which uses a laminar flow section to obtain low drag, does not tilt except when the vehicle is stationary. A high degree of redundancy is built into the vehicle; for example there are two motors and transmissions, the solar array is divided into seven parallel sub-arrays, and the power electronics is multiply redundant. Built entirely in the garage of a suburban house, the Australian Geographic Team Marsupial car cost less than US$50,000 to construct.
This final report for the Swiss Federal Office of Energy (SFOE) presents the results of a project that involves the building of a joint biogas plant serving 60 farmers and industrial companies with an annual processing capacity of 45,000 tons. The plant is to produce biogas to be fed into the gas mains and will not only reduce nutrient loading in a region with an extensive livestock industry but also reduce carbon dioxide emissions by using the gas as a motor fuel. The importance of the project with respect to both the environment and energy policy-making is discussed and the costs involved are examined. Details are presented on the technology used and on the material flows involved. Figures are quoted on energy production. The various biogenic substrates used, such as food wastes, waste oils, cereal wastes and used mushroom substrates, are discussed, as is the use of the solid and liquid outputs of the digester in farming activities.
AbstractBackground: Quality of life in Parkinson patients with subthreshold depression could be improved if the prevalence and symptom profile were better understood. Methods: Our study used standard DSM-IV and Judd criteria as well as motor, depression, and quality-of-life scales to investigate a sample of 110 nondemented Parkinson patients. This led to formation of nondepressed (48.2%), subthreshold depressed (25.5%), and depressed (26.4%) groups. Results: Quality of life was seen to be significantly lower in subthreshold depressed patients than in the nondepressed, and there were differences in the frequency of depressive symptoms that partially overlapped with nonmotor symptoms of vegetative origin in Parkinson's disease (appetite, sleep disorders). Key measures of depression (diminish...
A solar thermal powered aircraft powered by heat energy from the sun. A heat engine, such as a Stirling engine, is carried by the aircraft body for producing power for a propulsion mechanism, such as a propeller. The heat engine has a thermal battery in thermal contact with it so that heat is supplied from the thermal battery. A solar concentrator, such as reflective parabolic trough, is movably connected to an optically transparent section of the aircraft body for receiving and concentrating solar energy from within the aircraft. Concentrated solar energy is collected by a heat collection and transport conduit, and heat transported to the thermal battery. A solar tracker includes a heliostat for determining optimal alignment with the sun, and a drive motor actuating the solar concentrator into optimal alignment with the sun based on a determination by the heliostat.
Slurry characteristics have a significant impact on centrifugal pump performance. For instance, as particle size increases or the percent solids concentration increases, pump head and efficiency decrease. Therefore, before a slurry pump is selected, it is important to define the slurry characteristics as accurately as possible. The effect of the slurry characteristics on the head and efficiency of the centrifugal pump will be emphasized (the effect on flowrate is less significant). The effect of slurry characteristics is more predominant in smaller pumps (with smaller diameter impellers) than in larger pumps. The data and relationship between the various slurry parameters have been developed from correlations and nomographs published by pump vendors from their field data and test results. The information helps to avoid specifying an undersized pump/motor assembly for slurry service.
Deltombe T, Gustin T. Selective tibial neurotomy in the treatment of spastic equinovarus foot in hemiplegic patients: a 2-year longitudinal follow-up of 30 cases. Objective To assess the long-term efficacy of selective tibial neurotomy in the treatment of spastic equinovarus foot in hemiplegic patients. Design Intervention study (before-after trial) with an observational design and 2-year follow-up. Setting Spasticity group in a university hospital. Participants Hemiplegic patients (N=30) with spastic equinovarus foot. Intervention A selective neurotomy was performed at the level of the motor nerve branches of the tibial nerve. Main Outcome Measures Spasticity (Ashworth scale), muscle strength (Medical Research Council scale), passive ankle dorsiflexion, gait parameters (6 min walking test...
This paper quantifies the avoided CO{sub 2} emission due to the using, as vehicle fuel, of the alcohol produced in Brazil during the period 1995 - 2025. With this purpose, internal demand sceneries were elaborated for Otto cycle engines. The results suggest that the introduction of the flex-fuel and the increasing of the production and using of hydrated alcohol can reduce up to 1.23 Gt of CO{sub 2} equivalent during the period 2003 - 2025, representing an annual average of 53.5 Mt CO{sub 2} equivalent.
A program of tests were conducted in July 1986 at the Fast Flux Test Facility (FFTF) to demonstrate that the reactor could withstand a prototypic loss of flow (LOF) without scram without sustaining fuel damage. The reactor was taken to powers up to 50%, and the main primary coolant pump motors were tripped without scramming the control rods. This paper summarizes the analyses performed to demonstrate the maintenance of redundant protection for all design events as well as potential new events introduced by the test. The analyses focused on the following consequences: (1) unexpected test behavior; (2) transient overpower event during the test; and (3) LOF event during the test.
In this paper, research on pass schedule of tandem cold mill (TCM) is carried out. According to load (reduction, rolling force, motor power) balance, non-linear equations set with variables of inter-stand thickness is constructed. The pass schedule optimization is carried out by solving the non-linear equations set. As the traditional method, the Newton-Raphson method is used for solving the non-linear equations set. In this paper a new simple method is brought up. On basis of the monotone relations between thickness and load, the inter-stands thickness is adjusted dynamically. The solution of non-linear equations set can be converged by iterative calculation. This method can avoid the derivative calculation used by traditional method. So, this method is simple and calculation speed is high. It is suitable for on-line control. (author)
In this paper, research on pass schedule of tandem cold mill (TCM) is carried out. According to load (reduction, rolling force, motor power) balance, non-linear equations set with variables of inter-stand thickness is constructed. The pass schedule optimization is carried out by solving the non-linear equations set. As the traditional method, the Newton-Raphson method is used for solving the non-linear equations set. In this paper a new simple method is brought up. On basis of the monotone relations between thickness and load, the inter-stands thickness is adjusted dynamically. The solution of non-linear equations set can be converged by iterative calculation. This method can avoid the derivative calculation used by traditional method. So, this method is simple and calculation speed is high. It is suitable for on-line control. (author)
We have developed a chitosan/polyglycolic acid (PGA) artificial nerve graft which was previously used for bridge implantation of dog sciatic nerves across 30-mm long defects. Here we describe a clinical trial of this graft for repairing a 35-mm-long median nerve defect at elbow of a human patient. During the 3-year follow-up period, functional recovery of the injured median nerve was assessed by pinch gauge test, hydraulic hand dynamometry, static two-point discrimination and touch test with monofilaments, in couple with electrophysiological examinations. The motor and sensory function of the median nerve demonstrated an ongoing recovery postimplantation, reaching M4 and S3+ levels during the follow-up period. The results indicate that the chitosan/PGA artificial nerve graft could be used ...
Energy saving technologies in the railway vehicle traction field can be mainly categorized into two domains: reducing loss and increasing the regenerative energy. Energy saving technologies for the traction equipment by the use of power converters with less loss and high-efficiency permanent magnet synchronous motors are introduced. The regenerative brake related technologies are also presented as another measure to save the energy, including the improvement of the regenerative brake control and application of energy storage devices. It is concluded that the benefit of the energy saving technology is not only the energy saving itself but also downsizing traction equipments and reducing the maintenance work in the electrical railway system. Copyright Copyright 2010 Institute of Electrical E...
A solar thermal powered aircraft powered by heat energy from the sun. A Rankine-Brayton hybrid cycle heat engine is carried by the aircraft body for producing power for a propulsion mechanism, such as a propeller or other mechanism for enabling sustained free flight. The Rankine-Brayton engine has a thermal battery, preferably containing a lithium-hydride and lithium mixture, operably connected to it so that heat is supplied from the thermal battery to a working fluid. A solar concentrator, such as reflective parabolic trough, is movably connected to an optically transparent section of the aircraft body for receiving and concentrating solar energy from within the aircraft. Concentrated solar energy is collected by a heat collection and transport conduit, and heat transported to the thermal battery. A solar tracker includes a heliostat for determining optimal alignment with the sun, and a drive motor actuating the solar concentrator into optimal alignment with the ...
The treatment of chronic pain conditions continue to present a challenge to the medical field. Physical therapy treatment needs to approach the management of chronic pain differently than the approach used to resolve acute pain. Patients with chronic pain often have many factors that have perpetuated the pain condition. These factors, as well as pain itself, influence their ability to reactivate and perform functional daily activities. Physical therapists can begin to address some of the factors, including fear and deconditioning, by building confidence and body awareness in a self-care model including a slow graduated reactivation program. There is evidence that patients with chronic pain conditions have altered motor control that may be influencing reoccurrences and possible flares of pa...
A new implementation of a shear-force microscope is described that uses a shear-force detection system to perform topographical imaging of large areas (#approx#1x1 mm"2). This implementation finds very interesting application in the study of archeological or artistic samples. Three dc motors are used to move a sample during a scan, allowing the probe tip to follow the surface and to face height differences of several tens of micrometers. This large-area topographical imaging mode exploits new subroutines that were added to the existing homemade software; these subroutines were created in Microsoft VISUAL BASIC 6.0 programming language. With this new feature our shear-force microscope can be used to study topographical details over large areas of archaeological samples in a nondestructive way. We show results detecting worn reliefs over a coin.
Measurements of smoke and NO emissions from a direct-injection diesel engine have shown that they are indeed influenced by inlet port design, even though the swirl numbers for the ports may be identical. The swirl numbers of the three ports used (tangential port, helical port and helical port with masked valve) were measured on a steady-state test rig using a paddle-wheel anemometer and impulse swirl meter. Flow measurements were carried out under motoring conditions with a constant-temperature, hot-wire anemometer. Is was possible to find a correlation between flow data and exhaust data as far as the in-cylinder air motion over a certain time interval is concerned.
...February 2010 | PR 10/14 Intelligent Energy demonstrates zero emission scooter at Loughborough Suzuki Burgman Fuel Cell Scooter Loughborough University spin out company Intelligent Energy has partnered with ...the Suzuki Motor Corporation to develop the zero emission Suzuki Burgman Fuel Cell Scooter which was given its European unveiling and first demonstrations in London ...Show, and demonstrated in Loughborough today (Friday 5 February), the city friendly Burgman Fuel Cell Scooter builds upon the success of the Crosscage fuel cell motorbike unveiled ... The Fuel Cell Burgman takes the next step towards offering cleaner, more efficient motorcycles in a practical and accessible form with the potential ...
Background:- Children with oppositional defiant disorder/conduct disorder (ODD/CD) have shown deficits in -cool- abstract-cognitive, and -hot- reward-related executive function (EF) tasks. However, it is currently unclear to what extent ODD/CD is associated with neuropsychological deficits, independently of attention deficit hyperactivity disorder (ADHD). Methods:- Fifty-nine adolescents with a history of early-onset oppositional problems, 28 with pure ODD/CD symptoms and 31 with ADHD with or without ODD/CD, and 34 healthy controls were administered a task battery measuring motor response inhibition, sustained attention, cognitive flexibility and reward-related decision-making. Findings were analysed using dimensional and group analyses. Results:- In group analyses both groups with and wit...
A multivariate logistic regression model, based upon National Automotive Sampling System Crashworthiness Data System (NASS-CDS) data for calendar years 1999-2008, was developed to predict the probability that a crash-involved vehicle will contain one or more occupants with serious or incapacitating injuries. These vehicles were defined as containing at least one occupant coded with an Injury Severity Score (ISS) of greater than or equal to 15, in planar, non-rollover crash events involving Model Year 2000 and newer cars, light trucks, and vans. The target injury outcome measure was developed by the Centers for Disease Control and Prevention (CDC)-led National Expert Panel on Field Triage in their recent revision of the Field Triage Decision Scheme (American College of Surgeons, 2006). The ...
Entorhinal grid cells in mammals fire as a function of animal location, with spatially periodic response patterns. This nonlocal periodic representation of location, a local variable, is unlike other neural codes. There is no theoretical explanation for why such a code should exist. We examined how accurately the grid code with noisy neurons allows an ideal observer to estimate location and found this code to be a previously unknown type of population code with unprecedented robustness to noise. In particular, the representational accuracy attained by grid cells over the coding range was in a qualitatively different class from what is possible with observed sensory and motor population codes. We found that a simple neural network can effectively correct the grid code. To the best of our kn...
Well over 90 percent of all motorized transportation is fueled by products of petroleum, but the end of such widespread use of oil may be in sight. Among alternative fuels for land transportation, electricity appears to be the most promising, in part because it can be renewably produced and readily transmitted. The inadequacy and high cost of on-board storage of electrical energy present major challenges to widespread deployment of electric traction, and may do so for many years. On-board generation of electrical energy also presents challenges. The third means of powering electric traction is to provide for connection to the electricity grid while in motion. Grid-connected vehicles (GCVs) are an established feature of many cities and of much inter-city transportation, chiefly as electric ...
An economic evaluation is presented for the proposed plant for producing 11,414,000 gallons per year of fuel-grade alcohol from 150,000 tons of molasses. The project is economically attractive at a 1981 ethanol sales price of $2.00 per gallon, a 1981 molasses price of $85.00 per ton, and a plant capital investment of $27.45 MM. The evaluation description includes: investment, operating costs, revenues, and economic analysis. Included in appendices are detailed computer printouts for the following scenarios: the constant dollar, the uniform escalation, and the current dollar.
The U.S. Department of Energy (DOE) and the U.S. Council for Automotive Research (composed of automakers Ford, General Motors, and Chrysler) announced in January 2002 a new cooperative research effort. Known as 'FreedomCAR' (derived from 'Freedom' and 'Cooperative Automotive Research'), it represents DOE's commitment to developing public/private partnerships to fund high-risk, high-payoff research into advanced automotive technologies. Efficient fuel cell technology, which uses hydrogen to power automobiles without air pollution, is a very promising pathway to achieving the ultimate vision. The new partnership replaces and builds upon the Partnership for a New Generation of Vehicles initiative that ran from 1993 through 2001. The Advanced Power Electronics and Electric Machines (APEEM) subprogram within the FreedomCAR and Vehicle Technologies Program provides support and guidance for many cutting-edge ...
Mechanomyography (MMG) is the muscle surface oscillations that are generated by the dimensional change of the contracting muscle fibers. Because MMG reflects the number of recruited motor units and their firing rates, just as electromyography (EMG) is influenced by these two factors, it can be used to estimate the force exerted by skeletal muscles. The aim of this study was to demonstrate the feasibility of MMG for estimating the elbow flexion force at the wrist under an isometric contraction by using an artificial neural network in comparison with EMG. We performed experiments with five subjects, and the force at the wrist and the MMG from the contributing muscles were recorded. It was found that MMG could be utilized to accurately estimate the isometric elbow flexion force based on the v...
In this paper, an empirical model is developed for electricity consumption of the Jordanian industrial sector based on multivariate linear regression to identify the main drivers behind electricity consumption. In addition, projection of electricity consumption for the industrial sector based on time series forecasting is presented. It was found that industrial production outputs and capacity utilization are the two most important variables that affect demand on electrical power and the multivariate linear regression model can be used adequately to simulate industrial electricity consumption with very high coefficient of determination. To illustrate the importance of integrating energy efficiency within national energy plans, the impact of implementing high-efficiency motors was investigat...
A detailed chemical kinetic model to describe the autoignition of gasoline surrogate fuels is presented consisting of the fuels iso-octane, n-heptane, toluene, diisobutylene and ethanol. Model predictions have been compared with shock tube ignition delay time data for surrogates of gasoline over practical ranges of temperature and pressure, and the model has been found to be sensitive to both changes in temperature and pressure. Moreover, the model can qualitatively predict the observed synergistic and antagonistic non-linear blending behaviour in motor octane number (MON) for different combinations of primary reference fuels (PRFs) and non-PRFs by correlating calculated autoignition delay times from peak pressures and temperatures in the MON test to experimental MON values. The reasons for the blending behaviour are interpreted in terms autoignition chemistry. 37 refs., 11 figs., 4 tabs.
Purpose - This study aims to design and test some fixed-wing micro aerial vehicles (MAV). Design/methodology/approach - The MAV wing planform in this study was designed based on previous results and the need to reduce the weight of the MAV. The MAV had a wing planform with a 6 percent Gottingen-329 camber airfoil, a 20 swept-back leading edge and a straight trailing edge. The fuselage was designed to contain a motor, an electronic control system and a video camera with a built-in transmitter. The battery was located outside the fuselage to trim the center of gravity and enable the battery to be changed easily when it has run out. Two exaggerated vertical stabilizers were installed to prevent the MAV from rolling. The materials, the power plant and the electronics used to fabricate the MAV ...
A distillation column with an adjustable slope horizontal rectification section was constructed. A rotating screw brush was inserted into the section, which could be rotated from 0 to 600 rpm with an external motor. Distillation experiments were carried out using the system cyclohexane-heptane at total reflux at slopes of 0(horizontal), 5 and 10 degrees. Separation efficiency for the horizontal column was the highest of the three orientations, and was obtained as HETP from 0.04 to 0.16 m at F-factor of 0.05 to 0.4 m/s(kg/m{sup 3}){sup 1/2} in the range of 100 to 600 rpm. The HETP for each slope was roughly constant at a rotation speed of more than 300 rpm. The values of the pressure drop were found to be equivalent to those of one seventh to one fifth of conventional packed columns. (author)
Immune thrombocytopenic purpura (ITP), Guillain-Barre syndrome (GBS), and Hashimotos thyroiditis (HT) are autoimmune disorders caused by impaired self-tolerance mechanisms triggered by interaction between genetic and environmental factors. ITP is an immune-mediated destruction of platelets resulting in mucocutaneous bleeding, GBS is an ascending motor paralysis caused by an inflammatory demyelination of peripheral nerves, and HT is characterized by autoimmune-mediated destruction of the thyroid gland. The concurrent development of ITP and GBS has only rarely been reported in the literature, and GBS itself rarely occurs with other autoimmune disorders. We present a 21 year-old patient with known Hashimotos hypothyroidism that simultaneously developed GBS and ITP after an upper respiratory t...
The purpose of this study was to compare cardiopulmonary fitness and endurance in 9-11-year-old children with DCD against a group of typically developing children in Taiwan. The Movement ABC test was used to evaluate the motor abilities of children. Forty-one participants (20 children with DCD and 21 children without DCD) were recruited for this study. The cardiopulmonary tests included the 800-m run test and the peak oxygen consumption (peak VO2) test using the Bruce treadmill protocol. No significant differences in age, body height, body weight, body mass index, and percentage of body fat between children with DCD and without DCD were found. However, there were significant differences in the cardiopulmonary endurance tests between children with DCD and without DCD. Children with DCD had ...
We describe a fully automated bead puller system which uses stepping motors to position the bead, and an HP-8510 network analyzer to measure the resulting frequency shifts, both devices being under computer control. Longitudinal motion of the bead is used for measurement of cavity shunt impedance. In addition, azimuthal scans at fixed longitudinal position aid in determining the multipole character of higher-order modes. High sensitivity/accuracy is made possible by measuring phase shifts at the unperturbed resonant frequencies (rather than frequency shifts themselves), thereby permitting averaging factors of > 500 with only modest increases in data acquisition time. Sample measurements will be presented. A comprehensive analysis of the experimental results is presented in an accompanying paper.
This investigation of a brain cancer cluster in Missouri used two approaches to investigate associations with potential risk factors. In a case-control study in a rural town, we interviewed surrogates of cases and controls about potential risk factors. We found a statistically significant positive association of brain cancer with reported exposure to dental x-rays. Occupation was not associated with the cluster in the rural town. In a standardized proportional mortality study for the state of Missouri, we calculated the observed and expected proportion of brain cancers by occupation and industry in Missouri decedents. We found that motor vehicle manufacturers, beauty shop workers, managers and administrators, elementary school teachers, and hairdressers and cosmetologists had significantly elevated proportions of brain cancer. Brain tumors are inconsistently associated with occupation in the literature. Further study of brain cancer etiology with respect to dental ...
A new German-engineered articulated drilling tool that can take the vertical to the horizontal, using about eight metres of curve, was described. The Articulate Downhole Motor has the capability to run radii as long as 57 metres (the usual requirement is 15 metres), under full control. Its ability to rotate and slide while maintaining control is one of the major positives of the technology. The technology also includes a `positive` communication system in its steering tool. The deployment of the positive pulse retrievable measurement-while-drilling (MWD) system brings real-time tool face orientation and hole direction to the surface. In using the tool, formation composition is not an issue; it is designed to withstand any environment.
Hybrid vehicles have two power supplies as engine and electric motor which are used most efficiently corresponding to objects respectively to attain energy-saving and low pollution. In this paper, factors concerning the fuel economy of hybrid vehicles and potential thereof are examined, and the possibility of reducing fuel cost by half is described. As possible modes of highly efficient hybrid vehicles, series hybrid vehicles (SHEV) of conventional internal combustion engine, parallel hybrid vehicles using EV in combination, series-parallel hybrid vehicles (SPHV), series type fuel cell type vehicles, ceramic engine-turbo compound power generating SPHV as well as SHEV, and ceramics gas turbine engine power generating SHEV are mentioned. 10 refs., 14 figs.
Action potentials from the brain control the activity of spinal neural networks to produce, by as yet unknown mechanisms, a variety of motor behaviors. Particularly lacking are details on how identified descending neurons integrate diverse sensory inputs to generate specific locomotor patterns. We have examined the operations of the principal neurons in an intriguing midbrain nucleus, the nucleus of the medial longitudinal fasciculus (nMLF), in the larval zebrafish. The nMLF is the most rostral grouping of neurons that projects from the brain well into the spinal cord of teleost fishes, yet there is little direct physiological data available regarding its function. We report here that a distinct set of large, individually-identifiable neurons in nMLF (the MeL and MeM neurons) are activated...
Mutations or multiplications in a-synuclein gene cause familial forms of Parkinson disease or dementia with Lewy bodies (LB), and the deposition of wild-type a-synuclein as LB occurs as a hallmark lesion of these disorders, collectively referred to as synucleinopathies, implicating a-synuclein in the pathogenesis of synucleinopathy. To identify modifier genes of a-synuclein-induced neurotoxicity, we conducted an RNAi screen in transgenic C. elegans (Tg worms) that overexpress human a-synuclein in a pan-neuronal manner. To enhance the RNAi effect in neurons, we crossed a-synuclein Tg worms with an RNAi-enhanced mutant eri-1 strain. We tested RNAi of 1673 genes related to nervous system or synaptic functions, and identified 10 genes that, upon knockdown, caused severe growth/motor abnormalit...
Two branches of research are conducted in this thesis. The first deals with nonlinear combustion response as a mechanism for triggering combustion instabilities in solid rocket motors. A nonlinear wave equation is developed to study a wide class of combustion response functions to second-order in fluctuation amplitude. Conditions for triggering are derived from analysis of limit cycles, and regions of triggering are found in parametric space. Introduction of linear cross-coupling and quadratic self-coupling among the acoustic modes appears to be how the nonlinear combustion response produces triggering to a stable limit cycle. Regions of initial conditions corresponding to stable pulses were found, suggesting that stability depends on initial phase angle and harmonic content, as well as the composite amplitude, of the pulse. Also, dependence of nonlinear stability upon system parameters is considered. The second part of this thesis presents research for a ...
The ECOTEC combustion system and the architecture of the new Opel 2.2 l aluminum engine have been configured to achieve low noise and exhaust emissions. This power unit, employed in Germany for the first time in the Astra Coupe, already complies with the Euro IV emissions standard. It features minimum maintenance requirements and a long operating life. The DOHC spark-ignition engine with four valves per cylinder has two chain-driven camshafts, valve gear with roller cam followers and hydraulic lash adjusters. Two chain driven balancer shafts have been integrated into the engine block. The cylinder head and block, lower crankcase, oil pan, and cylinder head cover are all made of aluminum. A modular concept makes it possible to adapt the engine effectively to different vehicle concepts and markets. (orig.) [German] Das ECOTEC-Verbrennungssystem und die Motorarchitektur des neuen 2,2-l-Aluminium-Triebwerks von Opel sind auf niedrige Geraeusch- und Abgasemissionen ausgelegt. Das in ...
The strategy for building SASOL plants reflects a commitment to long-range planning. The first plant, which represented a large investment for a moderate production capacity, was built to establish a technology for reducing South Africa's dependence on imported motor fuels. After the success of the plant, SASOL made plans for a larger plant, which had to be justified solely on economic grounds. At that time, petroleum crude was cheap and plentiful, and the second plant was cancelled. But when OPEC formed and the price of petroleum crude was increased, the South African government reconsidered the plans for another SASOL plant. Furthermore, because the cost of fuels produced at Sasol I proved to be significantly insensitive to inflation and future OPEC price increases were expected, SASOL projected that a new, larger plant should make a profit within a few years after its initial operation. But OPEC prices and inflation have risen even faster than ...
The strategy for building SASOL plants reflects a commitment to long-range planning. The first plant, which represented a large investment for a moderate production capacity, was built to establish a technology for reducing South Africa's dependence on imported motor fuels. After the success of the plant, SASOL made plans for a larger plant, which had to be justified solely on economic grounds. At that time, petroleum crude was cheap and plentiful, and the second plant was cancelled. But when OPEC formed and the price of petroleum crude was increased, the South African government reconsidered the plans for another SASOL plant. Furthermore, because the cost of fuels produced at Sasol I proved to be significantly insensitive to inflation and future OPEC price increases were expected, SASOL projected that a new, larger plant should make a profit within a few years after its initial operation. But OPEC prices and inflation have risen even faster than ...
Eukaryotic genomes encode a zinc finger protein (ZPR1) with tandem ZPR1 domains. In response to growth stimuli, ZPR1 assembles into complexes with eukaryotic translation elongation factor 1A (eEF1A) and the survival motor neurons protein. To gain insight into the structural mechanisms underlying the essential function of ZPR1 in diverse organisms, we determined the crystal structure of a ZPR1 domain tandem and characterized the interaction with eEF1A. The ZPR1 domain consists of an elongation initiation factor 2-like zinc finger and a double-stranded {beta} helix with a helical hairpin insertion. ZPR1 binds preferentially to GDP-bound eEF1A but does not directly influence the kinetics of nucleotide exchange or GTP hydrolysis. However, ZPR1 efficiently displaces the exchange factor eEF1B from preformed nucleotide-free complexes, suggesting that it may function as a negative regulator of eEF1A activation. Structure-based mutational and complementation analyses reveal ...
Improvements in electric submersible pumping systems have resulted in a demonstrated downhole running life of one year for low horsepower units operating in 180 C brine. The implementation of a prototype pressurized lubrication system to prevent brine intrusion and loss of lubricating oil from the motor and protector sections has been successfully tested. Second generation pressurized lubrication systems have been designed and fabricated and will be utilized in downhole production pumping tests during FY84. Pumping system lifetime is currently limited by available power cable designs that are degraded by high-temperature brine. A prototype metal-sheathed power cable has been designed and fabricated and is currently undergoing destructive and nondestructive laboratory testing. This cable design has the potential for eliminating brine intrusion into the power delivery system through the use of a hermatically sealed cable from the surface to the downhole ...
Since 1998, Hydro Quebec Research Centre (IREQ), in collaboration with Gentilly-2, has been working on the development of inspection devices for the feeder tubes of CANDU power plants. The first tool to come out of this work was the Metar bracelet, now used throughout the CANDU utilities, consisting of 14 ultrasonic probes held in place in a rigid bracelet to measure the thickness of the pipes and moved around manually along the pipe. Following the success of the Metar, a motorized version, i.e. the Crawler, has been developed to inspect beyond the operator arm's reach to access hard to reach place or further down the pipes in the reactor. This new system has been tested at 3 different stations and will be commercially available soon. Finally, the same technology was used to develop a motorized 2-axis crack detection device to answer new concerns about the feeder. Other configurations, depending on the demands from the industry, could ...
In view of current trends in motor car development, the author investigates the increasing conflict between higher comfort and lower fuel consumption. The conflict results mainly from insufficient cooling water heating with consumption-optimized engines. So far, it was never necessary to analyze heat flow after cold starting and heat-up of the powertrain, to develop strategies for heat storage and distribution, to remove heat sinks and to use components multifunctionally. The contribution shows that a general heat management strategy for the whole vehicle will result in high potential fuel savings and improved thermal comfort. Using the example of a latent heat store, heating strategies for the engine and transmission system on the one hand and the passenger compartment on the other hand are developed, and the advantages are presented in detail. [German] Abgeleitet aus den Trends in der Fahrzeugentwicklung wird auf den immer staerker werdenden Konflikt zwischen den ...
This report describes the first phase of the AFS/DOE program on mathematical modeling of cupola behavior, covering the period May 19, 1989 to July 19, 1990. The objective of the program is to develop a comprehensive mathematical model of the cupola furnace for on-line and off-line process control and optimization. The work is being carried out by five organizations: Massachusetts Institute of Technology with responsibility for heat transfer and fluid flow modeling, and incorporation of the chemical models being developed by the University of Michigan team. Modern Equipment Company has the responsibility of compiling information on needed sensors for monitoring operation and providing materials data to be used for cupola input. General Motors, Central Foundry Division, is investigating the potential to augment the mathematical models with artificial intelligence programs. Lastly, General Motors Research laboratories are charged with providing ...
Some motor operated valves now have higher torque switch settings due to regulatory requirements to ensure valve operability with appropriate margins at design basis conditions. Verifying operability with these settings imposes higher stem loads during periodic inservice testing. These higher test loads increase stresses in the various valve internal parts which may in turn increase the fatigue usage factors. This increased fatigue is judged to be a concern primarily in the valve disks, seats, yokes, stems, and stem nuts. Although the motor operators may also have significantly increased loading, they are being evaluated by the manufacturers and are beyond the scope of this study. Two gate valves representative of both relatively weak and strong valves commonly used in commercial nuclear applications were selected for fatigue analyses. Detailed dimensional and test data were available for both valves from previous studies at the Idaho National ...
Excitotoxicity plays a major role in various neurological disorders. In this study, we explored the behavioral and neurotoxic effects of intraventricular NMDA administration in mice. After NMDA injection, acute seizures were followed by impairments in locomotor activity, motor performance on a rotarod, and climbing ability. Mice killed 1 day after NMDA administration showed increased synaptosomal reactive oxygen species ROS production and calcium concentration and decreased mitochondrial membrane potential, mitochondrial reductase activities, and neuronal membrane Na+, K+ -ATPase and mg2+ -ATPase activities. One and 3 days after excitotoxic injury, Golgi stains showed that dendritic length and spine density were significantly decreased in neurons of the hippocampal dentate gyrus. Some mice received honokiol, tea polyphenol plus memantine, and honokiol plus memantine prior to NMDA treatment; the occurrence of generalized seizures was attenuated, seizure scores were ...
Introduction The progressive growth of malignancies is accompanied by a decline in the immune response through mechanisms which are poorly understood. Apoptosis and induction of inflammation by tumor released cytokines as tumor escape mechanisms have been proposed to play an important role in colorectal carcinogenesis. Methods Expression of Tumor necrosis factor-alpha (TNF-?) was analyzed in colorectal cancer specimen and the cancer cell line HT-29 by immunohistochemistry and RT-PCR. TNF-? expression on protein and mRNA level were correlated with clinical characteristics and impact on survival. TNFR-1 was co-labelled with TNF-? and CD8+ cytotoxic T cells in immunofluorescence double staining experiments. Results: 94% (n?=?98/104) of the patients with CRC expressed TNF-?. High TNF-? express...
PurposeThe behavior of trigeminocardiac reflex (TCR) during maxillofacial surgeries has not yet been sufficiently studied and knowledge of its behavior is limited to some case reports. The present study aimed to assess the occurrence of TCR in bilateral sagittal split ramus osteotomy and to determine the possible effect of Gow-Gates block on its incidence. Materials and MethodsTwenty candidates for bilateral sagittal split ramus osteotomy (included were American Society of Anesthesiologists I Class III patients with a prognathism of 3 to 5 mm) were given routine general anesthesia after at least 12 hours of fasting. All patients received Gow-Gates mandibular nerve block on 1 random side (case ramus; the other side was used as the control) after induction of general anesthesia before surger...
In this article, a method of producing elastic ferromagnetic composite containing particles of chemical pure iron with sizes of 0.10-0.15 mm was described. The particles were dispersed in an elastic matrix of an elastic silicone rubber. The filling factor of composite by ferromagnetic particles and porous factors were changed in the range from 0.15 to 0.45. The samples of the obtained composite were placed in the magnetic field with induction of 0-8 T, produced by the Bitter-type magnet. The longitudinal magnetostriction of samples was measured by using a coaxial capacitor with a movable plate. It was found that the maximal relative elongation of samples was 4.81% and hysteresis of magnetostriction and also remanent magnetostriction amounted to 1.08%. A slow decay of remanent magnetostriction up to 0.14% in 10{sup 5} s was also observed.
The presence of washed or unwashed cellophane alone or together with a bleomycin, mitomycin C or hydrochlorothiazide, ('Esidrex') showed no appreciable effect on survival of either unirradiated or irradiated conidia. Irradiation for a period of 20min reduced the survival of conidia to 20%. The growth of irradiated conidia in the presence of bleomycin, mitomycin C or Esidrex is associated with a 2- to 3-fold increase in the frequency of gene convertants, but was not accompanied by an increase in point mutants. When conidia were grown on cellophane but otherwise treated as before the frequency of gene convertants was increased 8-fold, but induction of point mutants was negligible. This effect was the same for irradiated and unirradiated conidia. The environment created by the cellophane in contract with the medium appears to affect the action of each of the three compounds synergistically. (author).
Inductive electromagnetic launchers, or coilguns, use discrete solenoidal coils to accelerate a coaxial conductive armature. To date, Sandia has been using an internally developed code, SLINGSHOT, as a point-mass lumped circuit element simulation tool for modeling coilgun behavior for design and verification purposes. This code has shortcomings in terms of accurately modeling gun performance under stressful electromagnetic propulsion environments. To correct for these limitations, it was decided to attempt to closely couple two Sandia simulation codes, Xyce and ALEGRA, to develop a more rigorous simulation capability for demanding launch applications. This report summarizes the modifications made to each respective code and the path forward to completing interfacing between them.
An attempt is made to induce in mud crab (Scylla serrata) epileptiform activities that resemble the generalized epileptic seizures. Cerebral ganglion of crab was exposed in situ, to a convulsant drug pentylenetetrazole (PTZ) 100?mM, for induction of seizures. Also, crabs were pretreated with antiepileptic drug viz sodium valproate (120??mol/l) to inhibit epileptiform activities. The surface electrical discharges of cerebral ganglion were recorded using Unkelscope (MIT, USA) in control as well as experimental animals. The cerebral ganglion of crab showed a pattern of high cerebral electrical discharges after PTZ treatment compared to control. The sodium valproate promoted sedative action in control and prevented PTZ-mediated epileptiform discharges. Glutamate and GABA contents in cerebral g...
The spontaneous precipitation of calcium sulfate in supersaturated solutions over the temperature range between 25.0 and 80.0 C was investigated by monitoring the solution specific conductivity during desupersaturation. From measurements of the induction times preceding the onset of precipitation the surface energy of the forming solid, identified as gypsum, was found between ca. 12 and 25 mJ/m{sup 2} for the temperature range between 80.0 and 25.0 C, respectively. Kinetics analysis showed that over 50 C it is possible that anhydrous calcium sulfate is forming as a transient phase converting into the more stable calcium sulfate dihydrate. The linear dependence of the rates of precipitation on the relative solution supersaturation suggested a mechanism according to which the growth units are integrated into the active sites of the supercritical nuclei by surface diffusion. According to the morphological examination of the crystals it is possible that crystal growth ...
Lung cancer is still difficult to treat by current chemotherapeutic procedures. We recently found that MVL, an anti-HIV lectin from blue-green algae Microcystis viridis, also has antitumor activity. The objective of this study was to investigate apoptosis-inducing activity of recombinant MVL (R-MVL) and proteomic changes in A549 cells, and to identify the molecular pathways responsible for the anti-cancer action of R-MVL. We found that R-MVL induces A549 cells apoptosis in a dose-dependent manner by using MTT assay, fluorescent microscope (FM) and flow cytometry (FCM), and the IC50 was calculated to be 24.12??g/ml. Subsequently, 7 altered proteins in R-MVL-treated A549 cells were identified, including upregulated aldehyde dehydrogenase 1 and ?-actin, and five downregulated proteins: heat s...
Early failure of an induction-hardening carbon steel pipe, which was used to transport tailing slurry, was caused by pitting corrosion. The microstructure on the internal pipe surface layer was found being a mixture of martensite, pearlite and ferrite. In this work, the pitting corrosion behavior of each constitute in the microstructure of steel is investigated with electrochemical noise analyses; the electronic properties of passive films were studied with Mott-Schottky relationship. It is found that the passive films formed on the materials under investigation are highly disordered n-type semiconductors. The high-to-low pitting susceptibility is ferrite > martensite > pearlite. The pitting resistance is related to the semiconductive nature of the passive film formed on each constitute. The pitting susceptibility increases with the donor concentration in the passive films. (author)
Wild and tissue cultured plants of Portulaca grandiflora Hook. have shown to be able to decolorize a sulfonated diazo dye Navy Blue HE2R (NBHE2R) up to 98% in 40h. A significant induction in the activities of lignin peroxidase, tyrosinase and DCIP reductase was observed in the roots during dye decolorization. The wild plants and tissue cultures could independently decolorize and degrade NBHE2R into metabolites viz. N-benzylacetamide and 6-diazenyl-4-hydroxynaphthalene-2-sulfonic acid. A dye mixture and a textile effluent were also decolorized efficiently by P. grandiflora. The phytotoxicity study revealed reduction in the toxicity due to metabolites formed after dye degradation.
Summary Background Current management of egg allergy relies on egg elimination from the diet. It does not protect patients from reactions after accidental ingestion of the food and it has a negative influence on quality of life. To solve these problems, some desensitization protocols have been described that are safe and effective, but only one study of a rush regimen for egg with a small patient sample has been published. Objective To evaluate the safety, efficacy and immunologic effects of an oral rush desensitization protocol for immediate egg allergy. Methods Subjects aged 5 years or older with symptomatic IgE-mediated allergy to hen's egg underwent a 5-day oral tolerance induction regimen and were subsequently maintained on a regular egg intake. The variables studied were the reaction...
Each of the three cysteine residues in the Escherichia coli RecA protein was replaced with a number of other amino acids. To do this, each cysteine codon was first converted to a chain-terminating amber codon by oligonucleotide-directed mutagenesis. These amber mutants were then either assayed for function in different suppressor strains or reverted by a second round of mutagenesis with oligonucleotides that had random sequences at the amber codon. Thirty-three different amino acid substitutions were obtained. Mutants were tested for three functions of RecA: survival following UV irradiation, homologous recombination, and induction of the SOS response. It was found that although none of the cysteines is essential for activity, mutations at each of these positions can affect one or more of the activities of RecA, depending on the particular amino acid substitution. In addition, the cysteine at position 116 appears to be involved in the RecA-promoted cleavage of the ...
Low level radioactive wastes (concrete pieces) or materials to be melted such as burnt ashes of wastes are charged into a melting furnace. Then, gyrotron of a microwave generator is oscillated, and generated microwaves of a large power are introduced to a melting furnace by a waveguide. The microwaves are irradiated from an irradiator to a beam converging-type reflecting mirror antenna disposed opposite to the irradiator. Then, an antenna driving portion is operated to rotate and move the antenna in parallel. With such procedures, the microwaves of a large power are converged acutely in a beam-like manner to a predetermined range in the melting furnace, and the converged beams of the microwaves are scanned. This can generate heat from the inner side of the materials to be melted charged to the melting furnace by the induction loss and they are melted. (I.N.)
This article describes the complete microsporogenesis and pollen formation in cassava (Manihot esculenta Crantz) at the various developmental stages (pollen mother cell, meiosis, tetrads, early free spore, mid uninucleate, late uninucleate, binucleate and mature pollen grain). Light microscopy, transmission electron microscopy and confocal laser scanning microscopy were used for the study. Floral bud size and other inflorescence characteristics were correlated with specific stages of the microspore development. This association allows a rapid selection of floral buds with similar microspore developmental stages, useful when a large number of homogeneous cells are needed for analysis and for in vitro induction of androgenesis. This article also compares methods for digestion the exine wall ...
The results of following the oxidative degradation of a plastic-bonded explosive (PBX 9501) are reported. Into over 1100 sealed containers were placed samples of PBX 9501 and combinations of its components and aged at relatively low temperatures to induce oxidative degradation of the samples. One of the components of the explosive is a poly(ester urethane) polymer and the oxidative degradation of the samples were following by measuring the molecular weight change of the polymer by gel permeation chromatography (coupled with both differential refractive index and multiangle laser light scattering detectors). Multiple temperatures between 40 and 64 degreeC were used to accelerate the aging of the samples. Interesting induction period behavior, along with both molecular weight increasing (cro...
Ex vivo expanded peripheral blood progenitor cells (PBPC) have been shown to provide rapid neutrophil engraftment, and in some patients, to eliminate neutropenia after transplantation to support high-dose chemotherapy. However, the effect of expansion culture on stem cell content and potential loss of stem cells caused by induction of differentiation remains a concern. We have transplanted 21 patients with breast cancer with expanded autologous PBPC, with 11 patients receiving expanded PBPC as their sole hematopoietic cell source. In these studies, the CD34+ cells were selected and cultured for 10 days in defined media containing 100 ng/mL each of recombinant human stem cell factor (rhSCF), recombinant human granulocyte colony stimulating factor (rhG-CSF), and recombinant human megakaryocy...
The aim of this thesis is the design of a faults diagnosis-aiding system in a nuclear facility of the Cea. Actually the existing system allows the optimization of the production processes in regular operating conditions. Meanwhile during accidental events, the alarms, managed by threshold, are bringing no relevant information. To increase the reliability and the safety, the human operator needs a faults diagnosis-aiding system. The developed system, SECAPI, combines problem solving techniques and automatic learning techniques, that allow the diagnosis and the the simulation of various faults happening on nuclear facilities. Its reasoning principle uses case-based and rules-based techniques. SECAPI owns a learning module which reads out knowledge connected with faults. It can then simulate various faults, using the inductive logical computing. SECAPI has been applied on a radioactive tritium treatment operating channel, at the Cea with good results. (A.L.B.)
The feather has been widely used as a indicator tissue of metal exposure in birds. The feathers were collected from Tuskegee University poultry farm (TUPF) and Harrison Poultry farm (HPF) chicken and analyzed by Inductively Coupled Plasma Atomic Emission Spectroscopy for lead, cadmium, cobalt, chromium, and copper contaminations. The mean levels of lead, cadmium, cobalt, chromium, and copper in TUPF chicken were 3.67, 0.13, 12.23, 0.22, and 7.71 ppm, respectively, and in HPF chicken were 5.32, 0.096, 11.03, 0.15, and 8.06 ppm, respectively. The mean levels of these metals did not show any significant difference between TUPF and HPF chicken.
DNA methylation is considered as a potential cause of aberrations in regulation of gene expression during carcinogenesis. Therefore, changes in DNA methylation patterns may be targets for chemoprevention. In the present study, we investigated effects of all-trans retinoic acid (ATRA), vitamin D3, and resveratrol alone and in combination with adenosine analogues: 2-chloro-2'-deoxyadenosine (2CdA) and 9-beta-d-arabinosyl-2-fluoroadenine (F-ara-A), on methylation and expression of retinoic acid receptor beta 2 (RARbeta2) in MCF-7 and MDA-MB-231 breast cancer cell lines. Alterations in methylation and expression levels after treatment of cells with the tested compounds were evaluated by methylation-sensitive restriction analysis (MSRA) and real-time PCR, respectively. RARbeta2 promoter in the ...
The author explains current developments in high voltage cable technology and subsequently describes problems inherent in its application, from the users viewpoint, in municipal electricity supply. The planning of a high voltage cable network and the selection of a specific type of cable are not only dependent on the typical properties of various cables but to a major degree also on the feasible laying technique, the power transmitted, the costs, the stellation treatment of the high voltage network, the acceptance requirement, the inductive influence from telecommunication cable, thermal influences from the environment, eventual safeguards from mechanical and chemical damage to the network, frequency of failure and surveillance and breakdown location. In conclusion, the author portrays potential developments in the fields of high and maximum voltage cable from the perspectives of today.
This study was conducted to investigate the antibacterial effect of BSAP-254 on Bacillus cereus with the induced stress proteins. The BSAP-254 is an antimicrobial peptide isolated from soybean-fermenting bacteria, Bacillus subtilis SC-8. It had a narrow spectrum of activity against B. cereus group. The growth inhibitory effect of BSAP-254 (50??g/mL) reduced the population of B. cereus from >108 to 104 colony-forming units per milliliter within 30?min. In B. cereus exposed to BSAP-254, 14 intracellular proteins were differentially expressed as determined by 2-DE coupled with MS. Of the differentially expressed proteins identified, the stress protein GroEL, which is heat shock protein, was induced in B. cereus exposed to antibacterial peptide.
Field-annealed Co-based amorphous ribbon (Metglas? 2705M) with a meander structure is fabricated by MEMS technology and the giant magnetoimpedance (GMI) effects are studied at different magnetic fields and frequencies. The maximum longitudinal GMI ratio of the ribbon is 193.7% and the magnetic field sensitivity is 17.4%/Oe. The maximum GMI ratio of the meander ribbon is much larger than the single strip ribbon mainly due to the larger change ratio of inductance L. The sensitivity of an output U reach up to 10 V/A and U thermal fluctuation is less than 15 mV in the temperature range of ?20 to 40?C. This meander shape ribbon can be considered as a good candidate for the GMI-based sensor fabrication.
Human embryonic stem (ES) cells can undergo spontaneously differentiation in standard culture conditions, demonstrating that the undifferentiated state is relatively unstable. The heterogeneous expression of SSEA3 observed within human ES colonies, provides a means to examine undifferentiated stem cell substates. Through functional testing of single cells we have shown that undifferentiated ES cells can be segregated into functionally discrete subpopulations on the basis of SSEA3 expression: SSEA3(High), SSEA(Low) and SSEA3(Negative). Human ES subpopulations were found to be interconvertible, but they possess distinct properties when challenged to differentiate along the neural lineage. These data suggest that ES cells with pluripotent/self-renewal capacities can exhibit different responses to induction of differentiation. PMID:21763622
Objective: : Evaluate expression of inducible negative regulators of JAK/STAT pathway and their target proteins during the course of ligature-induced experimental periodontal disease in rats. Design: : Rats were sacrificed 07, 15 and 30days after disease induction for histological evaluation of periodontal inflammation and macroscopic analysis of alveolar bone loss. SOCS expression and the activation status of STAT1 and STAT3 were evaluated in gingival biopsies by real time PCR and Western blot. Results: : Ligature-induced model presented significant progressive bone loss from 7 to 30days. Inflammation was evident and similar for 07 and 15days; however, a decrease on severity at the end of the experimental period was observed. There was a significant (p<0.05) increase on SOCS1 and SOCS3 ge...
AbstractBackground: So far, infliximab (IFX) therapy for the treatment of Crohn's disease (CD) has generally been guided by clinical symptoms. Data on treatment response as ascertained by endoscopy in IFX therapy are scarce. The aims of this study were to measure the endoscopic response rate during IFX induction and maintenance therapy in luminal CD, and also evaluate the role of endoscopy in monitoring IFX therapy. Methods: Data obtained from 71 patients with active luminal CD and treated with IFX were analyzed retrospectively. The endoscopy findings were scored according to mucosal activity as: 0 (remission), 1-2 (mild), 3-4 (moderate), and 5-6 (severe). A positive endoscopic response was determined by a decrease in score of at least two points and mucosal healing was assigned a score of...
The present study was designed to determine the exercise intensity equivalent to the metabolic aerobic/anaerobic transition of alloxan diabetic rats, through lactate minimum test (LMT), and to evaluate the effects of swimming exercise at this intensity (LM) on the glucose and protein metabolism of these animals. Adult male Wistar rats received alloxan (SD, alloxan-injected rats that remained sedentary) intravenously (30 mg kg?1 body weight) for diabetes induction. As controls (SC, vehicle-injected rats that remained sedentary), vehicle-injected rats were utilized. Two weeks later, the animals were submitted to oral glucose tolerance test (oGTT) and LMT. After the tests, some of the animals were submitted to swimming exercise training [TC (vehicle-injected rats that performed a 6-week exerc...
The presence of washed or unwashed cellophane alone or together with a bleomycin, mitomycin C or hydrochlorothiazide, ('Esidrex') showed no appreciable effect on survival of either unirradiated or irradiated conidia. Irradiation for a period of 20min reduced the survival of conidia to 20%. The growth of irradiated conidia in the presence of bleomycin, mitomycin C or Esidrex is associated with a 2- to 3-fold increase in the frequency of gene convertants, but was not accompanied by an increase in point mutants. When conidia were grown on cellophane but otherwise treated as before the frequency of gene convertants was increased 8-fold, but induction of point mutants was negligible. This effect was the same for irradiated and unirradiated conidia. The environment created by the cellophane in contract with the medium appears to affect the action of each of the three compounds synergistically.
The paper describes novel analytical methods developed for the detection of previous neutron irradiation and reprocessing of illicit nuclear materials, which is an important characteristic of nuclear materials of unknown origin in nuclear forensics. Alpha spectrometry and inductively coupled plasma sector-field mass spectrometry (ICP-SFMS) using solution nebulization and direct, quasi-non-destructive laser ablation as sample introduction were applied for the measurement of trace-level "2"3"2U, "2"3"6U and plutonium isotopes deriving from previous neutron irradiation of uranium-containing nuclear materials. The measured radionuclides and isotope ratios give important information on the raw material used for fuel production and enable confirm the supposed provenance of illicit nuclear material.
Coilguns have the ability to provide magnetic pressure to projectiles which results in near constant acceleration. However, to achieve this performance and control projectile hearing, significant constraints are placed on the design of the coils. We are developing coils to produce an effective projectile base pressure of 100 MPa (1kbar) as a step toward reaching base pressures of 200 MPa. The design uses a scalable technology applicable to the entire range of breech to muzzle coils of a multi-stage launcher. This paper presents the design of capacitor-driven coils for launching nominal 50 mm, 350 gram projectiles. Design criteria, constraints, mechanical stress analysis, launcher performance, and test results are discussed.
Pro-inflammatory cytokines may directly influence the viability and metabolic function of colonic epithelial cells (CEC) as an early event in the development of inflammatory bowel disease. We report here that TNF-alpha+IFN-gamma induced a synergistic, concentration-dependent decline in butyrate oxidation, an essential energy supply, in HT-29 and DLD-1 cells. TNF-alpha+IFN-gamma induced a parallel profound decline in cell viability in HT-29 cells, but not in DLD-1 cells, where impairment of butyrate oxidation seemed to precede later occurrence of cell damage. TNF-alpha+INF-gamma induced CEC damage was independent on NO formation and involved the IFN-gamma signalling pathway as well as induction of apoptosis. If cytokines have similar effects in vivo, these may lead to energy deficiency and thus contribute to CEC damage and disturbance of the epithelial integrity.
Objective Over recent years the Internet has become an increasingly popular source of support and information for infertility, with a growing number of online support groups now available to individuals affected by fertility problems. The aims of the present study were therefore to explore the online experiences of individuals accessing infertility support groups via the Internet. Methods Ninety-five participants who were recruited from several online infertility support groups completed an online questionnaire containing a series of open-ended questions. Responses to the open-ended questions were analysed using inductive thematic analysis. Results The thematic analysis revealed five recurrent themes, which were labelled: `unique features of online social support', `improved relationship w...
SBA-15 supported nano-scaled copper oxide was synthesized by impregnation method via ultrasonic-assisted route. The removal test from gas mixture containing 0.1?vol.% hydrogen sulfide was carried out over this material at atmospheric conditions. The effects of the chemical nature of copper oxide and the textural properties of the material on removal capacity were studied. The materials before and after the removal test were analyzed by nitrogen adsorption, X-ray diffraction, Transmission Electron Microscope, X-ray photoelectron Spectroscopy, Fourier Transform Infrared Spectrometer and Inductive Coupled Plasma. The results showed that copper species are located predominantly in mesopore channels, existing as copper oxide nanoparticles. Mesopores are active sites for removal reaction. The ou...
Electromagnetic forming (EMF) is a forming process that relies on the inductive electromagnetic force to deform metallic workpiece at high speed. Calculation of the electromagnetic force is essential to understand the EMF process. However, accurate calculation requires complex numerical solution, in which the coupling between the electromagnetic process and the deformation of workpiece needs be considered. In this paper, an appropriate formula has been developed to calculate the electromagnetic force in metal work-piece in the sheet EMF process. The effects of the geometric size of coil, the material properties, and the parameters of discharge circuit on electromagnetic force are taken into consideration. Through the formula, the electromagnetic force at different time and in different positions of the workpiece can be predicted. The calculated electromagnetic force and magnetic field are in good agreement with the numerical and experimental results. The accurate ...
Abstract Epstein-Barr virus (EBV), which infects not only B cells, but also T cells and natural killer (NK) cells, is associated with multiple lymphoid malignancies. Recently, the proteasome inhibitor bortezomib was reported to induce apoptosis of EBV-transformed B cells. We evaluated the killing effect of this proteasome inhibitor on EBV-associated T lymphoma cells and NK lymphoma cells. First, we found that bortezomib treatment decreased the viability of multiple T and NK cell lines. No significant difference was observed between EBV-positive and EBV-negative cell lines. The decreased viability in response to bortezomib treatment was abrogated by a pan-caspase inhibitor. The induction of apoptosis was confirmed by flow cytometric assessment of annexin V staining. Additionally, cleavage o...
Using a case-study, inductive, narrative approach, this article explores the history, drivers, benefits, and barriers to the Bakun Hydroelectric Project in East Malaysia. Situated on the island of Borneo, Bakun Dam is a 204m high concrete face, rock filled dam on the Balui River in the Upper Rajang Basin in the rainforests of Sarawak. Bakun Dam and its affiliated infrastructure could be the single largest and most expensive energy project ever undertaken in Southeast Asia. Based on data collected through site visits, original field research in Sarawak, and more than 80 research interviews, the article begins by teasing out the complex history and drivers behind the Bakun project before identifying a set of potential social, political, and economic benefits the project could deliver. It the...
Recently, the precise isotope ratios of some refractory elements in meteorites have been reported using inductively coupled plasma mass spectrometry. The in situ decay of {sup 182}Hf (T{sub 1/2}=9 Myr), which was produced at the latest nucleosynthesis, is recognized in many meteorites as isotopic anomalies of its daughter isotope, {sup 182}W. The degrees of relative {sup 182}W isotopic deviation in extra-terrestrial and terrestrial silicate samples vary from +0.3% to {+-}0% related to the size of their parent bodies. One ready interpretation of its correlation is the difference in timing of metal-silicate separation in the parent bodies. Between the earth and meteorite parent bodies, the difference is calculated to be about four times of the half-life of {sup 182}Hf, equivalent to 36 Myr. (author)
Summary Background- Treatments that achieve sustainable steroid-free clinical remission in Crohn-s disease are needed; however, long-term steroid-sparing efficacy data are limited. Aim- To evaluate steroid-sparing efficacy and the impact of steroid discontinuation on adverse events during treatment of Crohn's disease with adalimumab in the phase III randomised, double-blind 1-year CHARM trial and for an additional 2-years in its open-label extension ADHERE. Methods- Steroid-free remission and response and steroid-sparing (-50% steroid dose reduction) remission rates were evaluated over 3-years in patients who were taking corticosteroids at CHARM baseline. Results- Of 778 patients randomised in CHARM (including those who did not achieve clinical response to open-label induction therapy), 31...
The free-electron laser (FEL) projects that are currently in progress in Japan are discussed. Particular attention is given to the storage ring FELs at the Electrotechnical Laboratory, the Institute for Molecular Physics, and the Kyushu University; the superconducting linear accelerator (SC linac) FELs being developed at the Japan Atomic Energy Research Institute; and the RF-linac FEL being developed by the Nuclear Engineering Research Laboratory of the University of Tokyo, the Institute of Scientific and Industrial Research of Osaka University, the Mitsubishi Electric Company, and Tokyo Institute of Technology. Consideration is also given to the microtron FEL being constructed at the Nihon University; the induction-linac and pulseline FELs of the Institute of Laser Engineering of Osaka University, the Institute of Physical and Chemical Research, the National Laboratory for High-Energy Physics, and ISAS; and the Smith-Purcell-effect FEL developed by Tohoku ...
Glycyrrhiza glabra root is one of the common traditional Chinese medicines and used as flavoring and sweetening agents for tobaccos, chewing gums, candies, toothpaste and beverages. While glycyrrhizin is one of the main components in the extract of G. glabra root and has been characterized, the other components have not been well characterized. The mechanism of growth activation of breast cancer MCF-7 cells, including the activation of Erk1/2 and Akt, and the transcriptional regulation of estrogen-responsive genes, was examined by means of sulforhodamine B, luciferase reporter gene, real-time RT-PCR and Western blotting assays after the induction of the cells with the extract of G. glabra root. The extract has similar activity to that induced by 17b-estradiol (E2), although glycyrrhizin di...