Genetic and bibliographic information: ARL6 [GenLibi
Full Text Available ARL6 ADP-ribosylation factor-like 6 human Bardet-Biedl Syndrome (MeSH) Nervous Syst...Diseases (C10.228.140.617) > Bardet-Biedl Syndrome (C10.228.140.617.200) Congenital, Hereditary, and Neonata...lities, Multiple (C16.131.077) > Bardet-Biedl Syndrome (C16.131.077.112) 99A0284114 ...
Kathleen Zettergren
2011-01-01
A 69 year old male with idiopathic Parkinson’s disease participated in a 60-minute, bi-weekly training program using the Nintendo Wii fit gaming system. Pre-test/post-test assessments included: 1) The Timed up and go (TUG), 2) The Berg Balance scale (BBS), 3) Self selected gait speed, 4) Fall history, and 5) Geriatric Depression Scale (GDS). After 8 weeks, the subject’s BBS score increased from 31 to 42 (35% improvement), the TUG decreased from 36.5 seconds to 24.1 seconds (34% improvement), ...
KATHLEEN ZETTERGREN; JESSICA FRANCA; MICHAEL ANTUNES; CHRISTOPHER LAVALLEE
2011-01-01
A 69 year old male with idiopathic Parkinson’s disease participated in a 60-minute, bi-weekly training program using the Nintendo Wii fit gaming system. Pre-test/post-test assessments included: 1) The Timed up and go (TUG), 2) The Berg Balance scale (BBS), 3) Self selected gait speed, 4) Fall history, and 5) Geriatric Depression Scale (GDS). After 8 weeks, the subject’s BBS score increased from 31 to 42 (35% improvement), the TUG decreased from 36.5 seconds to 24.1 seconds (34% improvement), ...
Sun, Ying
2011-01-01
This article proposes an informative exploratory tool, the functional boxplot, for visualizing functional data, as well as its generalization, the enhanced functional boxplot. Based on the center outward ordering induced by band depth for functional data, the descriptive statistics of a functional boxplot are: the envelope of the 50% central region, the median curve, and the maximum non-outlying envelope. In addition, outliers can be detected in a functional boxplot by the 1.5 times the 50% central region empirical rule, analogous to the rule for classical boxplots. The construction of a functional boxplot is illustrated on a series of sea surface temperatures related to the El Niño phenomenon and its outlier detection performance is explored by simulations. As applications, the functional boxplot and enhanced functional boxplot are demonstrated on children growth data and spatio-temporal U.S. precipitation data for nine climatic regions, respectively. This article has supplementary material online. © 2011 American Statistical Association.
Campi, Stefano; Gardner, Richard; Gronchi, Paolo;
2012-01-01
Variants of the brightness function of a convex body K in n-dimensional Euclidean are investigated. The Lambertian lightness function L(K; v , w ) gives the total reflected light resulting from illumination by a light source at infinity in the direction w that is visible when looking in the...... direction v . The partial brightness function R( K ; v , w ) gives the area of the projection orthogonal to v of the portion of the surface of K that is both illuminated by a light source from the direction w and visible when looking in the direction v . A class of functions called lightness functions is...... lightness functions....
Della Pia, Eduardo Antonio; Hansen, Randi Westh; Zoonens, Manuela; Martinez, Karen L.
Amphipols are amphipathic polymers that stabilize membrane proteins isolated from their native membrane. They have been functionalized with various chemical groups in the past years for protein labeling and protein immobilization. This large toolbox of functionalized amphipols combined with their...... surfaces for various applications in synthetic biology. This review summarizes the properties of functionalized amphipols suitable for synthetic biology approaches....
Markushevich, A I
2014-01-01
Entire Functions focuses on complex numbers and the algebraic operations on them and the basic principles of mathematical analysis.The book first elaborates on the concept of an entire function, including the natural generalization of the concept of a polynomial and power series. The text then takes a look at the maximum absolute value and the order of an entire function, as well as calculations for the coefficients of power series representing a given function, use of integrals, and complex numbers. The publication elaborates on the zeros of an entire function and the fundamen
Kantorovich, L V
1982-01-01
Functional Analysis examines trends in functional analysis as a mathematical discipline and the ever-increasing role played by its techniques in applications. The theory of topological vector spaces is emphasized, along with the applications of functional analysis to applied analysis. Some topics of functional analysis connected with applications to mathematical economics and control theory are also discussed. Comprised of 18 chapters, this book begins with an introduction to the elements of the theory of topological spaces, the theory of metric spaces, and the theory of abstract measure space
Millová, Katarína
London: Palgrave Macmillan, 2015, s. 60-80. ISBN 978-1-137-43995-6 R&D Projects: GA ČR GAP407/10/2410 Institutional support: RVO:68081740 Keywords : social dimension of successful development * structure of social functioning * resources of social functioning Subject RIV: AN - Psychology
It is a compilation of chapters written by active researchers and offer information and critical insights about semiconducting materials and devices, dielectric and ferroelectric materials, magnetic materials, composites and other functional materials. In the book, the functional materials are discussed from the mixed valences and stoichiometry points of view, to understand the structural evolution and transformation of different material systems - in particular, the role played by crystal structures in property control of functional materials using advanced characterization techniques. The book examines the properties, soft-chemistry preparations, electronic structures and crystal structures of transition and rare earth metals and their oxides. The book presents a strong argument that functional materials system is the future direction of the multidisciplinary research involving physics, chemistry, materials science and electrical engineering, with emphasis on device applications. Papers relevant to INIS are indexed separately
Bustince, H.; Fernández, J.; Mesiar, Radko; Montero, J.; Orduna, R.
2010-01-01
Roč. 72, 3-4 (2010), s. 1488-1499. ISSN 0362-546X R&D Projects: GA ČR GA402/08/0618 Institutional research plan: CEZ:AV0Z10750506 Keywords : t-norm * Migrative property * Homogeneity property * Overlap function Subject RIV: BA - General Mathematics Impact factor: 1.279, year: 2010 http://library.utia.cas.cz/separaty/2009/E/mesiar-overlap functions.pdf
Hahn, M
1996-01-01
Based on empirical evidence from a free word order language (German) we propose a fundamental revision of the principles guiding the ordering of discourse entities in the forward-looking centers within the centering model. We claim that grammatical role criteria should be replaced by indicators of the functional information structure of the utterances, i.e., the distinction between context-bound and unbound discourse elements. This claim is backed up by an empirical evaluation of functional centering.
Nambudiripad, K B M
2014-01-01
After presenting the theory in engineers' language without the unfriendly abstraction of pure mathematics, several illustrative examples are discussed in great detail to see how the various functions of the Bessel family enter into the solution of technically important problems. Axisymmetric vibrations of a circular membrane, oscillations of a uniform chain, heat transfer in circular fins, buckling of columns of varying cross-section, vibrations of a circular plate and current density in a conductor of circular cross-section are considered. The problems are formulated purely from physical considerations (using, for example, Newton's law of motion, Fourier's law of heat conduction electromagnetic field equations, etc.) Infinite series expansions, recurrence relations, manipulation of expressions involving Bessel functions, orthogonality and expansion in Fourier-Bessel series are also covered in some detail. Some important topics such as asymptotic expansions, generating function and Sturm-Lioville theory are r...
K.H.DTZ
2007-01-01
1 Results The lecture will address aspects of functional organometallics related to the development of novel organometallic materials.In chromium complexes of fused arenes-regio-and diastereoselectively accessible by chromium-templated benzannulation of arylcarbenes by alkynes[1]-a haptotropic migration of the chromium fragment along the π-face of fused arenes is controlled by both thermodynamics and the substitution pattern of the arene and the metal coligand sphere,and can be applied towards an organo...
Brun, Rita; Kuo, Braden
2010-05-01
Dyspepsia is a common term used for a heterogeneous group of abdominal symptoms. Functional dyspepsia (FD) is the focus of this review. The 2006 Rome III criteria defined FD and its subgroups, postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS). FD is a very common condition with a high prevalence throughout the world, adversely affecting the quality of life of patients. The pathophysiology of FD has been under investigation during the past two decades. Multiple mechanisms such as abnormal gastric emptying, visceral hypersensitivity, impaired gastric accommodation, and central nervous system factors are likely involved. Several tests are available for the assessment of various physiologic functions possibly involved in the pathogenesis of FD, and some of these could be used in clinical practice, helping to understand the abnormalities underlining patients' complaints. Currently, the possibilities of pharmacological therapy for FD are still limited, however, experience of using prokinetics, tricyclic antidepressants, selective serotonin-reuptake inhibitors (SSRIs), proton-pump inhibitors (PPIs), and several alternative techniques has been accumulated. The different combinations of alterations in physiologic gastrointestinal and central nervous system functions result in the very heterogeneous nature of FD so combined approaches to these patients could be beneficial in challenging cases. PMID:21180597
2005-01-01
2005200 The effect of body position changes on lung function, lung CT imaging and pathology in an oleic acid induced acute lung injury model. JI Xin-ping (戢新平), et al. Dept Emergency, 1st Affili Hosp, China Med Univ, Shenyang 110001. Chin J Tuberc Respir Dis, 2005;28(1) :33-36. Objective: To study the effect of body position changes on lung mechanics, oxygenation, CT images and pathology in an oleic acid-induced acute lung injury (ALl) model. Methods: The study groups con-
Is functional behavioral assessment functional?
2006-01-01
Abstract Traditional methods of discipline, like punishment, suspension, and expulsion have in the past seemed beneficial, on a short-term basis, against problem behavior in schools. Four schools in Norway have recently implemented Functional Behavior Assessment (FBA) as part of a pilot project, to test the School-Wide Positive Behavioral Support (SW-PBS). A completed FBA procedure reveals the setting events, the antecedents and the consequences around the problem behavior, which provides ...
The term lung function is often restricted to the assessment of volume time curves measured at the mouth. Spirometry includes the assessment of lung volumes which can be mobilised with the corresponding flow-volume curves. In addition, lung volumes that can not be mobilised, such as the residual volume, or only partially as FRC and TLC can be measured by body plethysmography combined with the determination of the airway resistance. Body plethysmography allows the correct positioning of forced breathing manoeuvres on the volume-axis, e.g. before and after pharmacotherapy. Adding the CO single breath transfer factor (TLCO), which includes the measurement of the ventilated lung volume using He, enables a clear diagnosis of different obstructive, restrictive or mixed ventilatory defects with and without trapped air. Tests of reversibility and provocation, as well as the assessment of inspiratory mouth pressures (PImax, P0.1) help to classify the underlying disorder and to clarify treatment strategies. For further information and to complete the diagnostic of disturbances of the ventilation, diffusion and/or perfusion (capillar-)arterial bloodgases at rest and under physical strain sometimes amended by ergospirometry are recommended. Ideally, lung function measurements are amended by radiological and nuclear medicine techniques. (orig.)
Kathleen Zettergren
2011-11-01
Full Text Available A 69 year old male with idiopathic Parkinson’s disease participated in a 60-minute, bi-weekly training program using the Nintendo Wii fit gaming system. Pre-test/post-test assessments included: 1 The Timed up and go (TUG, 2 The Berg Balance scale (BBS, 3 Self selected gait speed, 4 Fall history, and 5 Geriatric Depression Scale (GDS. After 8 weeks, the subject’s BBS score increased from 31 to 42 (35% improvement, the TUG decreased from 36.5 seconds to 24.1 seconds (34% improvement, gait speed increased from .26 m/s to .37 m/s (42% improvement and GDS scores remained unchanged. The Nintendo Wii Fit may be a viable alternative to independent exercise programs for people diagnosed with idiopathic PD.
KATHLEEN ZETTERGREN
2011-11-01
Full Text Available A 69 year old male with idiopathic Parkinson’s disease participated in a 60-minute, bi-weekly training program using the Nintendo Wii fit gaming system. Pre-test/post-test assessments included: 1 The Timed up and go (TUG, 2 The Berg Balance scale (BBS, 3 Self selected gait speed, 4 Fall history, and 5 Geriatric Depression Scale (GDS. After 8 weeks, the subject’s BBS score increased from 31 to 42 (35% improvement, the TUG decreased from 36.5 seconds to 24.1 seconds (34% improvement, gait speed increased from .26 m/s to .37 m/s (42% improvement and GDS scores remained unchanged. The Nintendo Wii Fit may be a viable alternative to independent exercise programs for people diagnosed with idiopathic PD
Asadchy, V S; Vehmas, J; Tretyakov, S A
2014-01-01
Conventional mirrors obey Snell's reflection law: a plane wave is reflected as a plane wave, at the same angle. To engineer spatial distributions of fields reflected from a mirror, one can either shape the reflector (for example, creating a parabolic reflector) or position some phase-correcting elements on top of a mirror surface (for example, designing a reflectarray antenna). Here we show, both theoretically and experimentally, that full-power reflection with general control over reflected wave phase is possible with a single-layer array of deeply sub-wavelength inclusions. These proposed artificial surfaces, metamirrors, provide various functions of shaped or nonuniform reflectors without utilizing any mirror. This can be achieved only if the forward and backward scattering of the inclusions in the array can be engineered independently, and we prove that it is possible using electrically and magnetically polarizable inclusions. The proposed sub-wavelength inclusions possess desired reflecting properties at...
Lee, S. R.; Park, S. K.; Kim, J. J. [Hanyang University College of Medicine, Seoul (Korea, Republic of); Jeon, H. J.; Jeon, H. S.; Kim, D. Y. [Gang Nam Hospital, Seoul (Korea, Republic of)
1984-09-15
Morphologic changes of spinal canal and dural sac during spinal movement (flexion-extension) were analysed and reported with the base of cross sectional anatomy, as early as 1942. After that, this movement was emphasized and used in myelography in many countries under the name of functional myelography, for accurate diagnosis of spinal stenosis as herniated disc, but nor used commonly in Korea. Authors analysed functional myelographic findings of 78 cases, 37 of normal and 41 of surgically confirmed herniated disc, to intend to confirm the necessity of spinal movement during myelography. The results were as follows; 1. In normal group, anterior border of dural sac is stright with flexion, but indented in extension at the level of intervertebral space and this indentation is less prominent at L5-S1. 2. In normal group with extension, posterior indentation of dural sac is more prominent at the level of intervertebral space than body, A-P diameter of dural sac is narrowed all the level of intervertebral space except L5-S1,and dural sac moved anteriorly (near to the posterior portion of spinal body or intervertebral space) at the level L5-S1 and all spinal body. 3. In disc patient, anterior indentation of dural sac is persist in both views (flexion and extension) and much more exaggerated with extension, but less prominent at L5-S1. 4. In herniated disc patient with extension, anterior movement of anterior dural border at the level of L5-S1 is much decreased than normal.
LaChapelle, J.
2013-01-01
Functional integrals are defined in terms of locally compact topological groups and their associated Banach-valued Haar integrals. This approach generalizes the functional integral scheme of Cartier and DeWitt-Morette. The definition allows a construction of functional Mellin transforms. In turn, the functional Mellin transforms can be used to define functional traces, logarithms, and determinants. The associated functional integrals are useful tools for probing function spaces in general and...
Functional inequalities for modified Bessel functions
Baricz, Árpád; Vuorinen, Matti
2010-01-01
In this paper our aim is to show some mean value inequalities for the modified Bessel functions of the first and second kinds. Our proofs are based on some bounds for the logarithmic derivatives of these functions, which are in fact equivalent to the corresponding Tur\\'an type inequalities for these functions. As an application of the results concerning the modified Bessel function of the second kind we prove that the cumulative distribution function of the gamma-gamma distribution is log-concave. At the end of this paper several open problems are posed, which may be of interest for further research.
Kargın, Levent; Kurt, Veli
2015-01-01
In this study, obtaining the matrix analog of the Euler's reflection formula for the classical gamma function we expand the domain of the gamma matrix function and give a infinite product expansion of sinπxP. Furthermore we define Riemann zeta matrix function and evaluate some other matrix integrals. We prove a functional equation for Riemann zeta matrix function.
This invention relates to the investigation of body function, especially small bowel function but also liver function, using bile acids and bile salts or their metabolic precursors labelled with radio isotopes and selenium or tellurium. (author)
Noncommutative Bessel symmetric functions
Novelli, Jean-Christophe; Thibon, Jean-Yves
2006-01-01
The consideration of tensor products of 0-Hecke algebra modules leads to natural analogs of the Bessel J-functions in the algebra of noncommutative symmetric functions. This provides a simple explanation of various combinatorial properties of Bessel functions.
Gersten, A.
1999-01-01
By applying projection operators to state vectors of coordinates we obtain subspaces in which these states are no longer normalized according to Dirac's delta function but normalized according to what we call "incomplete delta functions". We show that this class of functions satisfy identities similar to those satisfied by the Dirac delta function. The incomplete delta functions may be employed advantageously in projected subspaces and in the link between functions defined on the whole space ...
Functional Forms and Educational Production Functions
Montmarquette, C.; Mahseredjian, S.
1985-01-01
Different Functional Forms Are Proposed and Applied in the Context of Educational Production Functions. Three Different Specifications - the Linerar, Logit and Inverse Power Transformation (Ipt) - Are Used to Explain First Grade Students' Results to a Mathematics Achievement Test. with Ipt Identified As the Best Functional Form to Explain the Data, the Assumption of Differential Impact of Explanatory Variables on Achievement Following the Status of the Student As a Low Or High Achiever Is Ret...
Functional microorganisms for functional food quality.
Gobbetti, M; Cagno, R Di; De Angelis, M
2010-09-01
Functional microorganisms and health benefits represent a binomial with great potential for fermented functional foods. The health benefits of fermented functional foods are expressed either directly through the interactions of ingested live microorganisms with the host (probiotic effect) or indirectly as the result of the ingestion of microbial metabolites synthesized during fermentation (biogenic effect). Since the importance of high viability for probiotic effect, two major options are currently pursued for improving it--to enhance bacterial stress response and to use alternative products for incorporating probiotics (e.g., ice cream, cheeses, cereals, fruit juices, vegetables, and soy beans). Further, it seems that quorum sensing signal molecules released by probiotics may interact with human epithelial cells from intestine thus modulating several physiological functions. Under optimal processing conditions, functional microorganisms contribute to food functionality through their enzyme portfolio and the release of metabolites. Overproduction of free amino acids and vitamins are two classical examples. Besides, bioactive compounds (e.g., peptides, γ-amino butyric acid, and conjugated linoleic acid) may be released during food processing above the physiological threshold and they may exert various in vivo health benefits. Functional microorganisms are even more used in novel strategies for decreasing phenomenon of food intolerance (e.g., gluten intolerance) and allergy. By a critical approach, this review will aim at showing the potential of functional microorganisms for the quality of functional foods. PMID:20830633
Rough function model and rough membership function
Wang Yun; Guan Yanyong; Huang Zhiqin
2008-01-01
Two pairs of approximation operators, which are the scale lower and upper approximations as well as the real line lower and upper approximations, are defined. Their properties and antithesis characteristics are analyzed. The rough function model is generalized based on rough set theory, and the scheme of rough function theory is made more distinct and complete. Therefore, the transformation of the real function analysis from real line to scale is achieved. A series of basic concepts in rough function model including rough numbers, rough intervals, and rough membership functions are defined in the new scheme of the rough function model. Operating properties of rough intervals similar to rough sets are obtained. The relationship of rough inclusion and rough equality of rough intervals is defined by two kinds of tools, known as the lower (upper) approximation operator in real numbers domain and rough membership functions. Their relative properties are analyzed and proved strictly, which provides necessary theoretical foundation and technical support for the further discussion of properties and practical application of the rough function model.
Entire functions sharing one small function
LI Yun-tong; CAO Yao
2007-01-01
The uniqueness problem of entire functions sharing one small function was studied. By Picard's Theorem, we proved that for two transcendental entire functions f (z) and g(z), a positive integer n≥9, and a(z) (not identically eaqual to zero) being a common small function related to f (z) and g(z), if f n(z)(f(z)-1)f'(z) and gn(z)(g'z)-1)g'(z) share a(z) CM, where CM is counting multiplicity, then g(z)≡f (z). This is an extended version of Fang and Hong's theorem [ Fang ML, Hong W, A unicity theorem for entire functions concerning differential polynomials, Journal of Indian Pure Applied Mathematics, 2001, 32 (9): 1343-1348].
On $ \\delta $-perfect functions
C. K. Basu
2004-01-01
$ \\delta $-continuous [6] and $ \\delta $-perfect [5] functions are both introduced by T.~Noiri in the similar fashion as continuous and perfect functions. The purpose of the present paper is to investigate several properties of $ \\delta$-perfect functions and also to determine some topological properties which are preserved by $ \\delta$-continuous $ \\delta$-perfect functions.
Relations between Lipschitz functions and convex functions
无
2005-01-01
[1]Zajicek, J., On the differentation of convex functions in finite and infinite dimensional spaces, Czech J. Math.,1979, 29: 340-348.[2]Hu, T. C., Klee, V. L., Larman, D. G., Optimization of globally convex functions, SIAM J. Control Optim., 1989,27: 1026-1047.[3]Cepedello Boiso, M., Approximation of Lipschitz functions by △-convex functions in Banach spaces, Israel J.Math., 1998, 106: 269-284.[4]Asplund, E., Frechet differentiability of convex functions, Acta Math., 1968, 121: 31-47.[5]Johnson, J. A., Lipschitz spaces, Pacific J. Math, 1974, 51: 177-186.[6]Stromberg, T., The operation of infimal convolution, Dissert. Math., (Rozprawy Mat.), 1996, 325: 58.[7]Kadison, R. V., Ringrose, J. R., Fundamentals of the theory of operator algebras, volume Ⅰ: Elementary Theory,Graduate Studies in Math., vol. 15, Amer. Math. Soc., 1997.[8]Phelps, R. R., Convex functions,monotone operators and differentiability, Lect. Notes in Math., vol. 1364,Springer-Verlag, 1977.[9]Lindenstrauss, J., On operators which attain their norm, Israel J. Math., 1963, 1: 139-148.[10]Press, D., Gateaux differentiable functions are somewhere Frechet differentiable, Rend. Circ. Mat. Palermo,1984, 33: 122-133.[11]Press, D., Differentiability of Lipschitz functions on Banach spaces, J. Funct. Anal., 1990, 91:312-345.[12]Lindenstrauss, J., Press, D., On Frechet differentiability of Lipschitz maps between Banach spaces, Annals of Math., 2003, 157: 257-288.[13]Press, D., Gateaux differentiable Lipschitz functions need not be Frechet differentiable on a residual set, Supplemento Rend. Circ. Mat. Palermo, Serie Ⅱ, 1982, 2: 217-222.
Generalised Elliptic Functions
England, Matthew
2011-01-01
We consider multiply periodic functions, sometimes called Abelian functions, defined with respect to the period matrices associated with classes of algebraic curves. We realise them as generalisations of the Weierstras P-function using two different approaches. These functions arise naturally as solutions to some of the important equations of mathematical physics and their differential equations, addition formulae, and applications have all been recent topics of study. The first approach discussed sees the functions defined as logarithmic derivatives of the sigma-function, a modified Riemann theta-function. We can make use of known properties of the sigma function to derive power series expansions and in turn the properties mentioned above. This approach has been extended to a wide range of non hyperelliptic and higher genus curves and an overview of recent results is given. The second approach defines the functions algebraically, after first modifying the curve into its equivariant form. This approach allows...
Filter function synthesis by Gegenbauer generating function
Pavlović Vlastimir D.
2006-01-01
Full Text Available Low-pass all-pole transfer functions with non-monotonic amplitude characteristic in the pass-band and at least (n -1 flatness conditions for ω = 0 are considered in this paper. A new class of filters in explicit form with one free parameter is obtained by applying generating functions of Gegenbauer polynomials. This class of filters has good selectivity and good shape of amplitude characteristics in the pass-band. The amplitude characteristics of these transfer functions have gain in the upper part of pass-band with respect to the gain for ω = 0. This way we have greater margin of attenuation in the upper part of the pass-band. This means a greater tolerance of elements or for elements with given tolerances, greater ambient temperature changes. The appropriate choice of the free parameter enables us to generate filter functions obtained with Chebyshev polynomials of the first and second kind and Legendre polynomials.
Meromorphic functions sharing four small functions
It is well known that if two nonconstant meromorphic functions f and g on the complex plane C have the same inverse images counted with multiplicities for four distinct values, then g is a special type of f. In this paper, we will show that the above result remains valid if f and g share four distinct small functions counted with multiplicities truncated by 2. This is the best truncation level. (author)
Raket, Lars Lau
We propose a direction it the field of statistics which we will call functional object analysis. This subfields considers the analysis of functional objects defined on continuous domains. In this setting we will focus on model-based statistics, with a particularly emphasis on mixed......-effect formulations, where the observed functional signal is assumed to consist of both fixed and random functional effects. This thesis takes the initial steps toward the development of likelihood-based methodology for functional objects. We first consider analysis of functional data defined on high...
Thomsen, Søren Steffen
2009-01-01
functions have received a huge amount of attention due to new attacks on widely used hash functions. This PhD thesis, having the title "Cryptographic Hash Functions", contains both a general description of cryptographic hash functions, including their applications and expected properties as well as some...... well-known designs, and also some design and cryptanalysis in which the author took part. The latter includes a construction method for hash functions and four designs, of which one was submitted to the SHA-3 hash function competition, initiated by the U.S. standardisation body NIST. It also includes...
Confinement from Correlation Functions
Fister, Leonard
2013-01-01
We compute the Polyakov loop potential in Yang--Mills theory from the fully dressed primitively divergent correlation functions only. This is done in a variety of functional approaches ranging from functional renormalisation group equations over Dyson--Schwinger equations to two-particle irreducible functionals. We present a confinement criterion that links the infrared behaviour of propagators and vertices to the Polyakov loop expectation value. The present work extends the works of [1-3] to general functional methods and sharpens the confinement criterion presented there. The computations are based on the thermal correlation functions in the Landau gauge calculated in [4-6].
Sun, Ying
2012-08-03
This article proposes functional median polish, an extension of univariate median polish, for one-way and two-way functional analysis of variance (ANOVA). The functional median polish estimates the functional grand effect and functional main factor effects based on functional medians in an additive functional ANOVA model assuming no interaction among factors. A functional rank test is used to assess whether the functional main factor effects are significant. The robustness of the functional median polish is demonstrated by comparing its performance with the traditional functional ANOVA fitted by means under different outlier models in simulation studies. The functional median polish is illustrated on various applications in climate science, including one-way and two-way ANOVA when functional data are either curves or images. Specifically, Canadian temperature data, U. S. precipitation observations and outputs of global and regional climate models are considered, which can facilitate the research on the close link between local climate and the occurrence or severity of some diseases and other threats to human health. © 2012 International Biometric Society.
Functionalized diamond nanoparticles
Beaujuge, Pierre M.
2014-10-21
A diamond nanoparticle can be functionalized with a substituted dienophile under ambient conditions, and in the absence of catalysts or additional reagents. The functionalization is thought to proceed through an addition reaction.
Lott, Steven
2015-01-01
This book is for developers who want to use Python to write programs that lean heavily on functional programming design patterns. You should be comfortable with Python programming, but no knowledge of functional programming paradigms is needed.
Extraocular muscle function testing
Extraocular muscle function testing examines the function of the eye muscles. A health care provider observes the movement of ... evaluate weakness or other problem in the extraocular muscles. These problems may result in double vision or ...
Babusci, D.; Dattoli, G.; Germano, B.; Martinelli, M. R.; Ricci, P. E.
2011-01-01
We use the operator method to evaluate a class of integrals involving Bessel or Bessel-type functions. The technique we propose is based on the formal reduction of these family of functions to Gaussians.
Dependence for functional data
Valencia García, Dalia Jazmín
2014-01-01
Measuring dependence is a basic question when dealing with functional observations. It is of great interest to know the effect that one or more functional variables can have on other ones, and even predict values of one variable from another. Although, in the functional context, this theory has not been as extensively studied,some techniques to measure dependence in functional data have already been implemented, providing a single value which represents the degree of relation between the sets...
Parton Fragmentation Functions
Metz, Andreas
2016-01-01
The field of fragmentation functions of light quarks and gluons is reviewed. In addition to integrated fragmentation functions, attention is paid to the dependence of fragmentation functions on transverse momenta and on polarization degrees of freedom. Higher-twist and di-hadron fragmentation functions are considered as well. Moreover, the review covers both theoretical and experimental developments in single-inclusive hadron production in electron-positron annihilation, deep-inelastic lepton-nucleon scattering, and proton-proton collisions.
Chemical functionalization of graphene
Boukhvalov, D. W.; Katsnelson, M I
2008-01-01
Experimental and theoretical results on chemical functionalization of graphene are reviewed. Using hydrogenated graphene as a model system, general principles of the chemical functionalization are formulated and discussed. It is shown that, as a rule, 100% coverage of graphene by complex functional groups (in contrast with hydrogen and fluorine) is unreachable. A possible destruction of graphene nanoribbons by fluorine is considered. The functionalization of infinite graphene and graphene nan...
Pseudolinear functions and optimization
Mishra, Shashi Kant
2015-01-01
Pseudolinear Functions and Optimization is the first book to focus exclusively on pseudolinear functions, a class of generalized convex functions. It discusses the properties, characterizations, and applications of pseudolinear functions in nonlinear optimization problems.The book describes the characterizations of solution sets of various optimization problems. It examines multiobjective pseudolinear, multiobjective fractional pseudolinear, static minmax pseudolinear, and static minmax fractional pseudolinear optimization problems and their results. The authors extend these results to locally
Phylogenetic molecular function annotation
Barbara E Engelhardt; Jordan, Michael I.; Repo, Susanna T; Brenner, Steven E
2009-01-01
It is now easier to discover thousands of protein sequences in a new microbial genome than it is to biochemically characterize the specific activity of a single protein of unknown function. The molecular functions of protein sequences have typically been predicted using homology-based computational methods, which rely on the principle that homologous proteins share a similar function. However, some protein families include groups of proteins with different molecular functions. A phylogenetic ...
Monotone Boolean functions are an important object in discrete mathematics and mathematical cybernetics. Topics related to these functions have been actively studied for several decades. Many results have been obtained, and many papers published. However, until now there has been no sufficiently complete monograph or survey of results of investigations concerning monotone Boolean functions. The object of this survey is to present the main results on monotone Boolean functions obtained during the last 50 years
Montanaro, Ashley; Osborne, Tobias J.
2008-01-01
In this paper we introduce the study of quantum boolean functions, which are unitary operators f whose square is the identity: f^2 = I. We describe several generalisations of well-known results in the theory of boolean functions, including quantum property testing; a quantum version of the Goldreich-Levin algorithm for finding the large Fourier coefficients of boolean functions; and two quantum versions of a theorem of Friedgut, Kalai and Naor on the Fourier spectra of boolean functions. In o...
Graphomania: learning function plots
Leskovšek, Gregor
2013-01-01
In the first part of our thesis Graphomania: learning function plots (hereinafter Graphomania) we present profesional applications of our current problem space and a drawing graphs of functions, manipulation of the current features: zoom in, zoom out, translate = pan add vertical poles and horizontal and oblique asymptotes in the following programs: (1) Draw Function Graphs (rechneronline.de/function-graphs/), (2) Derive (mathematical assistant for your PC, version 6.10), (3) GeoGebra 4.2 (ge...
Mohsen Razzaghi
2000-01-01
Full Text Available A direct method for finding the solution of variational problems using a hybrid function is discussed. The hybrid functions which consist of block-pulse functions plus Chebyshev polynomials are introduced. An operational matrix of integration and the integration of the cross product of two hybrid function vectors are presented and are utilized to reduce a variational problem to the solution of an algebraic equation. Illustrative examples are included to demonstrate the validity and applicability of the technique.
Rosenstand, Claus Andreas Foss; Laursen, Per Kyed
2013-01-01
How does one manage functional power relations between leading functions in vision driven digital media creation, and this from idea to master during the creation cycle? Functional power is informal, and it is understood as roles, e.g. project manager, that provide opportunities to contribute to...... method is collaborative practice studies including action research and practice studies; combined with solid industrial experience....
Anderson, Deborah S.; Kristiansen, Connie M.
1990-01-01
Discusses the Attitude Functions Inventory (AFI), which assesses the extent to which a person's attitude fulfills each of four psychological functions. Reports findings of a study, involving 249 undergraduates, that tested the construct validity of the AFI. Suggests that the AFI provides conceptually meaningful measures of the functions of…
Isotopic functions, or ratios of two isotopic variables, are used to verify Pu and U measurements of spent fuels in reprocessing plants. Systematic methods have been developed for forming and evaluating isotopic functions. This paper describes the method used at Battelle to form and evaluate isotopic functions. The data base at Battelle contains measurements and calculations for the fuel from 35 reactors
Clinical functional MRI. Presurgical functional neuroimaging
Stippich, C. (ed.) [Heidelberg Univ. (Germany). Div. of Neuroradiology
2007-07-01
Functional magnetic resonance imaging (fMRI) permits noninvasive imaging of the ''human brain at work'' under physiological conditions. This is the first textbook on clinical fMRI. It is devoted to preoperative fMRI in patients with brain tumors and epilepsies, which are the most well-established clinical applications. By localizing and lateralizing specific brain functions, as well as epileptogenic zones, fMRI facilitates the selection of a safe treatment and the planning and performance of function-preserving neurosurgery. State of the art fMRI procedures are presented, with detailed consideration of the physiological and methodological background, imaging and data processing, normal and pathological findings, diagnostic possibilities and limitations, and other related techniques. All chapters are written by recognized experts in their fields, and the book is designed to be of value to beginners, trained clinicians and experts alike. (orig.)
D'Hoker, Eric; Gurdogan, Omer; Vanhove, Pierre
2015-01-01
We consider properties of modular graph functions, which are non-holomorphic modular functions associated with the Feynman graphs for a conformal scalar field theory on a two-dimensional torus. Such functions arise, for example, in the low energy expansion of genus-one Type II superstring amplitudes. We demonstrate that these functions are sums, with rational coefficients, of special values of single-valued elliptic multiple polylogarithms, which will be introduced in this paper. This insight suggests the many interrelations between these modular graph functions (a few of which were motivated in an earlier paper) may be obtained as a consequence of identities involving elliptic polylogarithms.
Implementing function spreadsheets
Sestoft, Peter
: that of turning an expression into a named function. Hence they proposed a way to define a function in terms of a worksheet with designated input and output cells; we shall call it a function sheet. The goal of our work is to develop implementations of function sheets and study their application to...... realistic examples. Therefore, we are also developing a simple yet comprehensive spreadsheet core implementation for experimentation with this technology. Here we report briefly on our experiments with function sheets as well as other uses of our spreadsheet core implementation....
Transfer function combinations
Zhou, Liang
2012-10-01
Direct volume rendering has been an active area of research for over two decades. Transfer function design remains a difficult task since current methods, such as traditional 1D and 2D transfer functions, are not always effective for all data sets. Various 1D or 2D transfer function spaces have been proposed to improve classification exploiting different aspects, such as using the gradient magnitude for boundary location and statistical, occlusion, or size metrics. In this paper, we present a novel transfer function method which can provide more specificity for data classification by combining different transfer function spaces. In this work, a 2D transfer function can be combined with 1D transfer functions which improve the classification. Specifically, we use the traditional 2D scalar/gradient magnitude, 2D statistical, and 2D occlusion spectrum transfer functions and combine these with occlusion and/or size-based transfer functions to provide better specificity. We demonstrate the usefulness of the new method by comparing to the following previous techniques: 2D gradient magnitude, 2D occlusion spectrum, 2D statistical transfer functions and 2D size based transfer functions. © 2012 Elsevier Ltd.
Adaptive functional linear regression
Comte, Fabienne
2011-01-01
We consider the estimation of the slope function in functional linear regression, where scalar responses are modeled in dependence of random functions. Cardot and Johannes [2010] have shown that a thresholded projection estimator can attain up to a constant minimax-rates of convergence in a general framework which allows to cover the prediction problem with respect to the mean squared prediction error as well as the estimation of the slope function and its derivatives. This estimation procedure, however, requires an optimal choice of a tuning parameter with regard to certain characteristics of the slope function and the covariance operator associated with the functional regressor. As this information is usually inaccessible in practice, we investigate a fully data-driven choice of the tuning parameter which combines model selection and Lepski's method. It is inspired by the recent work of Goldenshluger and Lepski [2011]. The tuning parameter is selected as minimizer of a stochastic penalized contrast function...
Multistate nested canalizing functions
Adeyeye, J O; Laubenbacher, R; Li, Y
2013-01-01
The concept of a nested canalizing Boolean function has been studied over the course of the last decade in the context of understanding the regulatory logic of molecular interaction networks, such as gene regulatory networks. Such functions appear preferentially in published models of such networks. Recently, this concept has been generalized to include multi-state functions, and a recursive formula has been derived for their number, as a function of the number of variables. This paper carries out a detailed analysis of the class of nested canalizing functions over an arbitrary finite field. Furthermore, the paper generalizes the concept further, and derives a closed formula for the number of such generalized functions. The paper also derives a closed formula for the number of equivalence classes under permutation of variables. This is motivated by the fact that two nested canalizing functions that differ by a permutation of the variables share many important properties with each other. The paper contributes ...
Marine Functional Foods and Functional Ingredients
Hurst, D.
2006-01-01
This briefing paper gives insights into the issues surrounding marine functional foods and highlights opportunities for researchers in the marine sciences and food sciences areas to engage in collaborative research. It will be used as the basis for further consultation with the research community and firms in the marine and food sectors and to assist in exploring and prioritising research themes.
Functional Explanation and the Function of Explanation
Lombrozo, Tania; Carey, Susan
2006-01-01
Teleological explanations (TEs) account for the existence or properties of an entity in terms of a function: we have hearts because they pump blood, and telephones for communication. While many teleological explanations seem appropriate, others are clearly not warranted--for example, that rain exists for plants to grow. Five experiments explore…
Counting with symmetric functions
Mendes, Anthony
2015-01-01
This monograph provides a self-contained introduction to symmetric functions and their use in enumerative combinatorics. It is the first book to explore many of the methods and results that the authors present. Numerous exercises are included throughout, along with full solutions, to illustrate concepts and also highlight many interesting mathematical ideas. The text begins by introducing fundamental combinatorial objects such as permutations and integer partitions, as well as generating functions. Symmetric functions are considered in the next chapter, with a unique emphasis on the combinatorics of the transition matrices between bases of symmetric functions. Chapter 3 uses this introductory material to describe how to find an assortment of generating functions for permutation statistics, and then these techniques are extended to find generating functions for a variety of objects in Chapter 4. The next two chapters present the Robinson-Schensted-Knuth algorithm and a method for proving Pólya’s enu...
Weakly dependent functional data
Hörmann, Siegfried; 10.1214/09-AOS768
2010-01-01
Functional data often arise from measurements on fine time grids and are obtained by separating an almost continuous time record into natural consecutive intervals, for example, days. The functions thus obtained form a functional time series, and the central issue in the analysis of such data consists in taking into account the temporal dependence of these functional observations. Examples include daily curves of financial transaction data and daily patterns of geophysical and environmental data. For scalar and vector valued stochastic processes, a large number of dependence notions have been proposed, mostly involving mixing type distances between $\\sigma$-algebras. In time series analysis, measures of dependence based on moments have proven most useful (autocovariances and cumulants). We introduce a moment-based notion of dependence for functional time series which involves $m$-dependence. We show that it is applicable to linear as well as nonlinear functional time series. Then we investigate the impact of ...
Relativistic plasma dispersion functions
Robinson, P. A.
1986-05-01
The known properties of plasma dispersion functions (PDF's) for waves in weakly relativistic, magnetized, thermal plasmas are reviewed and a large number of new results are presented. The PDF's required for the description of waves with small wave number perpendicular to the magnetic field (Dnestrovskii and Shkarofsky functions) are considered in detail; these functions also arise in certain quantum electrodynamical calculations involving strongly magnetized plasmas. Series, asymptotic series, recursion relations, integral forms, derivatives, differential equations, and approximations for these functions are discussed as are their analytic properties and connections with standard transcendental functions. In addition a more general class of PDF's relevant to waves of arbitrary perpendicular wave number is introduced and a range of properties of these functions are derived.
Pisani, Pablo
2015-01-01
We present a pedagogical exposition of some applications of functional methods in quantum field theory: we use heat-kernel and zeta-function techniques to study the Casimir effect, the pair production in strong electric fields, quantum fields at finite temperature and beta-functions for a self-interacting scalar field, QED and pure Yang-Mills theories. The more recent application to the UV/IR mixing phenomenon in noncommutative theories is also discussed in this framework.
Functional Capacity Evaluation & Disability
Chen, Joseph J.
2007-01-01
Function, Impairment, and Disability are words in which many physicians have little interest. Most physicians are trained to deal with structure and physiology and not function and disability. The purpose of this article is to address some of the common questions that many physicians have with the use of functional capacity evaluation and disability and also to provide a unifying model that can explain the medical and societal variables in predicting disability. We will first define the funct...
Quasiplurisubharmonic Green functions
Coman, Dan; 10.1016/j.matpur.2009.05.010
2009-01-01
Given a compact K\\"ahler manifold $X$, a quasiplurisubharmonic function is called a Green function with pole at $p\\in X$ if its Monge-Amp\\`ere measure is supported at $p$. We study in this paper the existence and properties of such functions, in connection to their singularity at $p$. A full characterization is obtained in concrete cases, such as (multi)projective spaces.
Irreversible computable functions
Hoyrup, Mathieu
2014-01-01
The strong relationship between topology and computations has played a central role in the development of several branches of theoretical computer science: foundations of functional programming, computational geometry, computability theory, computable analysis. Often it happens that a given function is not computable simply because it is not continuous. In many cases, the function can moreover be proved to be non-computable in the stronger sense that it does not preserve computability: it map...
Broker, Reinier
2010-01-01
The moduli space of principally polarized abelian surfaces is parametrized by three Igusa functions. In this article we investigate a new way to evaluate these functions by using Siegel Eisenstein series. We explain how to compute the Fourier coefficients of certain Siegel modular forms using classical modular forms of half-integral weight. One of the results in this paper is an explicit algorithm to evaluate the Igusa functions to a prescribed precision.
Hash functions in Cryptography
Grah, Joseph Sterling
2008-01-01
This thesis is concerned with giving both an overview of the application of hash functions in cryptography and a presentation of today's standard cryptographic hash functions. Cryptographic hash functions are a valuable tool in cryptography. They are applied in many areas of information security to provide protection of the authenticity of messages; data integrity verification which prevents modification of data from going undetected, time stamping and digital signature scheme.
Mirce Functionability Equation
Dr Jezdimir Knezevic
2014-08-01
Full Text Available Scientific principles and concepts expressed through the laws, equations and formulas are the bedrock for the prediction of the deign-in functionality performance of any engineering creation. However, there is no equivalent when the in-service functionability performance predictions have to be made. Hence, Mirce Mechanics has been created at the MIRCE Akademy to fulfil the roll. The main purpose of this paper is to present the development and application of Mirce Functionability Equation which is the bedrock for the prediction of the functionability performance of maintainable systems.
Ding Yi
2009-01-01
In this article, the author derives a functional equation η(s)=［(π/4)s-1/2√2/πг(1-s)sin(πs/2)]η(1-s) of the analytic function η(s) which is defined by η(s)=1-s-3-s-5-s+7-s…for complex variable s with Re s>1, and is defined by analytic continuation for other values of s. The author proves (1) by Ramanujan identity (see [1], [3]). Her method provides a new derivation of the functional equation of Riemann zeta function by using Poisson summation formula.
Knopp, Konrad
1996-01-01
This is a one-volume edition of Parts I and II of the classic five-volume set The Theory of Functions prepared by renowned mathematician Konrad Knopp. Concise, easy to follow, yet complete and rigorous, the work includes full demonstrations and detailed proofs.Part I stresses the general foundation of the theory of functions, providing the student with background for further books on a more advanced level.Part II places major emphasis on special functions and characteristic, important types of functions, selected from single-valued and multiple-valued classes.
The function of the lungs is primarily the function as a gas exchanger: the venous blood returning to the lungs is arterialized with oxygen in the lungs and the arterialized blood is sent back again to the peripheral tissues of the whole body to be utilized for metabolic oxygenation. Besides the gas exchanging function which we call ''respiratory lung function'' the lungs have functions that have little to do with gas exchange itself. We categorically call the latter function of the lungs as ''nonrespiratory lung function''. The lungs consist of the conductive airways, the gas exchanging units like the alveoli, and the interstitial space that surrounds the former two compartments. The interstitial space contains the blood and lymphatic capillaries, collagen and elastic fibers and cement substances. The conductive airways and the gas exchanging units are directly exposed to the atmosphere that contains various toxic and nontoxic gases, fume and biological or nonbiological particles. Because the conductive airways are equipped with defense mechanisms like mucociliary clearance or coughs to get rid of these toxic gases, particles or locally produced biological debris, we are usually free from being succumbed to ill effects of inhaled materials. By use of nuclear medicine techniques, we can now evaluate mucociliary clearance function, and other nonrespiratory lung functions as well in vivo
Artin, Emil
2015-01-01
This brief monograph on the gamma function was designed by the author to fill what he perceived as a gap in the literature of mathematics, which often treated the gamma function in a manner he described as both sketchy and overly complicated. Author Emil Artin, one of the twentieth century's leading mathematicians, wrote in his Preface to this book, ""I feel that this monograph will help to show that the gamma function can be thought of as one of the elementary functions, and that all of its basic properties can be established using elementary methods of the calculus."" Generations of teachers
Perceptual Audio Hashing Functions
Emin Anarım
2005-07-01
Full Text Available Perceptual hash functions provide a tool for fast and reliable identification of content. We present new audio hash functions based on summarization of the time-frequency spectral characteristics of an audio document. The proposed hash functions are based on the periodicity series of the fundamental frequency and on singular-value description of the cepstral frequencies. They are found, on one hand, to perform very satisfactorily in identification and verification tests, and on the other hand, to be very resilient to a large variety of attacks. Moreover, we address the issue of security of hashes and propose a keying technique, and thereby a key-dependent hash function.
This appendix provides a brief definition of each of the 43 work functions for the 67 NPP units from North America and Western Europe that were the basis for the data in Appendix II. This information is provided to help the reader understand this data or to compare a given situation or plan to these functions. It is NOT intended to endorse this particular identification of workforce functions, as there is considerable variability in NPP workforce functions and organization worldwide based upon factors such as technology, national norms and culture, labour rules and laws, and industry practices
Functionalized surfaces and surface functionalization of nanomaterials
Tahir, Muhammad Nawaz
2006-01-01
Nature leads, we follow. But nanotechnologists are in hot pursuit, in designing controllable structures that can mimic naturally occurring and artificially synthesized materials on a common platform. The supramolecular chemistry concerns the investigation of nature principles to produce fascinating complexed and functional molecular assemblies, as well as the utilization of these principles to generate novel devices and materials, potentially useful for sensing, catalysis, transport and other...
Normal Functions As A New Way Of Defining Computable Functions
Leszek Dubiel
2004-01-01
Full Text Available Report sets new method of defining computable functions. This is formalization of traditional function descriptions, so it allows to define functions in very intuitive way. Discovery of Ackermann function proved that not all functions that can be easily computed can be so easily described with Hilbert’s system of recursive functions. Normal functions lack this disadvantage.
Normal Functions as a New Way of Defining Computable Functions
Leszek Dubiel
2004-01-01
Full Text Available Report sets new method of defining computable functions. This is formalization of traditional function descriptions, so it allows to define functions in very intuitive way. Discovery of Ackermann function proved that not all functions that can be easily computed can be so easily described with Hilbert's system of recursive functions. Normal functions lack this disadvantage.
Gardner, Richard J.; Kiderlen, Markus
associative, must be one of 40 explicitly given types. In particular, this is the case for operations between pairs of arbitrary, or continuous, or differentiable functions. The term pointwise means that (f ∗g)(x) = F(f(x), g(x)), for all x ∈ A and some function F of two variables. Several results in the same...
Funkcionalna androgenizacija: Functional hyperandrogenism:
Kocijančič, Andreja; Legan, Mateja
2001-01-01
Functional hyperandrogenism is common endocrinological disorder of premenopausal women characterized by hyperandrogenism, hirsutism with or without androgenic alopecia and chronic anovulation. The controversy regardingthe pathophysiological mechanism underlying the disease still persists. Insulin resistance and hyperinsulinism are now well recognized features of obese women with functional hyperandrogenism and accepted pathogenetic factor of disorder in obese patients. Insulin enhances lutheo...
Thyroid function in pregnancy☆
Leung, Angela M.
2012-01-01
Iodine is required for the production of thyroid hormones. Normal thyroid function during pregnancy is important for both the mother and developing fetus. This review discusses the changes in thyroid physiology that occur during pregnancy, the significance of thyroid function tests and thyroid antibody titers assessed during pregnancy, and the potential obstetric complications associated with maternal hypothyroidism.
... like asthma, chronic obstructive lung disease (COPD), or cystic fibrosis on lung function. ■■ Identify early changes in lung function that might show a need for a change in treatment. ■■ Detect narrowing in the airways. ■■ Decide if a ...
Knudsen, Lars Ramkilde; Rechberger, Christian; Thomsen, Søren Steffen
2007-01-01
state. We propose two concrete hash functions, Grindahl-256 and Grindahl-512 with claimed security levels with respect to collision, preimage and second preimage attacks of 2^128 and 2^256, respectively. Both proposals have lower memory requirements than other hash functions at comparable speeds and...
Functional and cognitive grammars
Anna Siewierska
2011-01-01
This paper presents a comprehensive review of the functional approach and cognitive approach to the nature of language and its relation to other aspects of human cognition. The paper starts with a brief discussion of the origins and the core tenets of the two approaches in Section 1. Section 2 discusses the similarities and differences between the three full-fledged structural functional grammars subsumed in the functional approach： Halliday＇s Systemic Functional Grammar （SFG）, Dik＇s Functional Grammar （FG）, and Van Valin＇s Role and Reference Grammar （RRG）. Section 3 deals with the major features of the three cognitive frameworks： Langacker＇s Cognitive Grammar （CG）, Goldberg＇s Cognitive Construction Grammar （CCG）, and Croft＇s Radical Construction Grammar （RCG）. Section 4 compares the two approaches and attempts to provide a unified functional-cognitive grammar. In the last section, the author concludes the paper with remarks on the unidirectional shift from functional grammar to cognitive grammar that may indicate a reinterpretation of the traditional relationship between functional and cognitive models of grammar.
Construction of Resilient Functions
ZHANG Jie; WEN Qiao-yan
2005-01-01
Based on the relationship between nonlinearity and resiliency of a multi-output function, we present a method for constructing nonintersecting linear codes from packing design. Through these linear codes, we obtain n-variable, moutput, t-resilient functions with very high nonlinearity.Their nonlinearities are currently the best results for most of cases.
Pick, Luboš; John, Oldrich; Fucík, Svatopluk
2012-01-01
This is the first part of the second revised and extended edition of a well established monograph. It is an introduction to function spaces defined in terms of differentiability and integrability classes. It provides a catalogue of various spaces and benefits as a handbook for those who use function spaces to study other topics such as partial differential equations. Volum
Lind, Morten
2011-01-01
purpose of the present paper is to serve as a companion paper to this introduction by explaining the basic principles used in MFM for representation of control functions. A theoretical foundation for modeling control functions is presented and modeling examples are given for illustration....
Functional Magnetic Resonance Imaging
Voos, Avery; Pelphrey, Kevin
2013-01-01
Functional magnetic resonance imaging (fMRI), with its excellent spatial resolution and ability to visualize networks of neuroanatomical structures involved in complex information processing, has become the dominant technique for the study of brain function and its development. The accessibility of in-vivo pediatric brain-imaging techniques…
Modeling Protein Domain Function
Baker, William P.; Jones, Carleton "Buck"; Hull, Elizabeth
2007-01-01
This simple but effective laboratory exercise helps students understand the concept of protein domain function. They use foam beads, Styrofoam craft balls, and pipe cleaners to explore how domains within protein active sites interact to form a functional protein. The activity allows students to gain content mastery and an understanding of the…
... of the clotting process in the body ( in vivo ). A person with normal platelet function test results may still experience excessive bleeding or inappropriate clotting during and after a surgery. Most samples for platelet function testing are only stable for a very short period ...
Group Contest Success Functions
Münster, Johannes
2008-01-01
Eine contest success function beschreibt, wie in einem Wettkampf die Gewinnwahrscheinlichkeiten von den Einsätzen der Beteiligten abhängen. Dieser Aufsatz verallgemeinert die auf Skaperdas (1996) und Clark und Riis (1998) zurückgehende axiomatische Fundierung von contest success functions, indem er Wettkämpfe zwischen Gruppen untersucht.
2003-01-01
This interactive tutorial on MATLAB covers the following: Create M-files, scripts, and functions., Write HELP comments for the functions., Determine the order in which MATLAB chooses to execute entities with identical names.The interactions involve entering MATLAB instructions and observing the outcomes. Self-check questions are provided to help learners determine their level of understanding of the content presented.
properties and luminosity functions
Hektor Monteiro
2007-01-01
Full Text Available In this article, we present an investigation of a sample of 1072 stars extracted from the Villanova Catalog of Spectroscopically Identified White Dwarfs (2005 on-line version, studying their distribution in the Galaxy, their physical properties and their luminosity functions. The distances and physical properties of the white dwarfs are determined through interpolation of their (B-V or (b-y colors in model grids. The solar position relative to the Galactic plane, luminosity function, as well as separate functions for each white dwarf spectral type are derived and discussed. We show that the binary fraction does not vary significantly as a function of distance from the Galactic disk out to 100 pc. We propose that the formation rates of DA and non-DAs have changed over time and/or that DAs evolve into non-DA types. The luminosity functions for DAs and DBs have peaks possibly related to a star burst event.
Ramsay, J O
1997-01-01
Scientists today collect samples of curves and other functional observations. This monograph presents many ideas and techniques for such data. Included are expressions in the functional domain of such classics as linear regression, principal components analysis, linear modelling, and canonical correlation analysis, as well as specifically functional techniques such as curve registration and principal differential analysis. Data arising in real applications are used throughout for both motivation and illustration, showing how functional approaches allow us to see new things, especially by exploiting the smoothness of the processes generating the data. The data sets exemplify the wide scope of functional data analysis; they are drwan from growth analysis, meterology, biomechanics, equine science, economics, and medicine. The book presents novel statistical technology while keeping the mathematical level widely accessible. It is designed to appeal to students, to applied data analysts, and to experienced researc...
Purely Functional Structured Programming
Obua, Steven
2010-01-01
The idea of functional programming has played a big role in shaping today's landscape of mainstream programming languages. Another concept that dominates the current programming style is Dijkstra's structured programming. Both concepts have been successfully married, for example in the programming language Scala. This paper proposes how the same can be achieved for structured programming and PURELY functional programming via the notion of LINEAR SCOPE. One advantage of this proposal is that mainstream programmers can reap the benefits of purely functional programming like easily exploitable parallelism while using familiar structured programming syntax and without knowing concepts like monads. A second advantage is that professional purely functional programmers can often avoid hard to read functional code by using structured programming syntax that is often easier to parse mentally.
Minguzzi, E.
2010-09-01
Every time function on spacetime gives a (continuous) total preordering of the spacetime events which respects the notion of causal precedence. The problem of the existence of a (semi-)time function on spacetime and the problem of recovering the causal structure starting from the set of time functions are studied. It is pointed out that these problems have an analog in the field of microeconomics known as utility theory. In a chronological spacetime the semi-time functions correspond to the utilities for the chronological relation, while in a K-causal (stably causal) spacetime the time functions correspond to the utilities for the K + relation (Seifert’s relation). By exploiting this analogy, we are able to import some mathematical results, most notably Peleg’s and Levin’s theorems, to the spacetime framework. As a consequence, we prove that a K-causal (i.e. stably causal) spacetime admits a time function and that the time or temporal functions can be used to recover the K + (or Seifert) relation which indeed turns out to be the intersection of the time or temporal orderings. This result tells us in which circumstances it is possible to recover the chronological or causal relation starting from the set of time or temporal functions allowed by the spacetime. Moreover, it is proved that a chronological spacetime in which the closure of the causal relation is transitive (for instance a reflective spacetime) admits a semi-time function. Along the way a new proof avoiding smoothing techniques is given that the existence of a time function implies stable causality, and a new short proof of the equivalence between K-causality and stable causality is given which takes advantage of Levin’s theorem and smoothing techniques.
Minguzzi, E
2009-01-01
Every time function on spacetime gives a (continuous) total preordering of the spacetime events which respects the notion of causal precedence. The problem of the existence of a (semi-)time function on spacetime and the problem of recovering the causal structure starting from the set of time functions are studied. It is pointed out that these problems have an analog in the field of microeconomics known as utility theory. In a chronological spacetime the semi-time functions correspond to the utilities for the chronological relation, while in a K-causal (stably causal) spacetime the time functions correspond to the utilities for the K^+ relation (Seifert's relation). By exploiting this analogy, we are able to import some mathematical results, most notably Peleg's and Levin's theorems, to the spacetime framework. As a consequence, we prove that a K-causal (i.e. stably causal) spacetime admits a time function and that the time or temporal functions can be used to recover the K^+ (or Seifert) relation which indeed...
Sethi, S; Sethi, Shiv
2001-01-01
We attempt to constrain the luminosity function of Gamma Ray Bursts (GRBs) from the observed number count--flux relation and the afterglow redshift data. We assume three classes of luminosity functions for our analysis: (a) Log-normal distribution, (b) Schechter distribution, and (c) Scale-free distribution. We assume several models of the evolution of the GRB population for each luminosity function. Our analysis shows that: (a) log-normal is the only luminosity function that is compatible with both the observations. This result is independent of the GRB evolution model, (b) for log-normal function, the average photon luminosity $L_0$ and the width of the luminosity function $\\sigma$ that are compatible with both the observations fall in the range: $10^{55} sec^{-1} \\la L_0 \\la 10^{56} sec^{-1}$ and $2 \\la \\sigma \\la 3$, (c) the agreement of observations with other luminosity functions requires the GRB population to evolve more strongly than the evolution of the star-formation rate of the universe.
The modulus squared of a class of wavefunctions defined on phase space is used to define a generalized family of Q or Husimi functions. A parameter λ specifies orderings in a mapping from the operator vertical bar ψ)(σ vertical bar to the corresponding phase space wavefunction, where σ is a given fiducial vector. The choice λ = 0 specifies the Weyl mapping and the Q-function so obtained is the usual one when vertical bar σ) is the vacuum state. More generally, any choice of λ in the range (-1, 1) corresponds to orderings varying between standard and anti-standard. For all such orderings the generalized Q-functions are non-negative by construction. They are shown to be proportional to the expectation of the system state ρ-hat with respect to a generalized displaced squeezed state which depends on λ and position (p, q) in phase space. Thus, when a system has been prepared in the state ρ-hat, a generalized Q-function is proportional to the probability of finding it in the generalized squeezed state. Any such Q-function can also be written as the smoothing of the Wigner function for the system state ρ-hat by convolution with the Wigner function for the generalized squeezed state
Functional Performance of Pyrovalves
Bement, Laurence J.
1996-01-01
Following several flight and ground test failures of spacecraft systems using single-shot, 'normally closed' pyrotechnically actuated valves (pyrovalves), a government/industry cooperative program was initiated to assess the functional performance of five qualified designs. The goal of the program was to improve performance-based requirements for the procurement of pyrovalves. Specific objectives included the demonstration of performance test methods, the measurement of 'blowby' (the passage of gases from the pyrotechnic energy source around the activating piston into the valve's fluid path), and the quantification of functional margins for each design. Experiments were conducted in-house at NASA on several units each of the five valve designs. The test methods used for this program measured the forces and energies required to actuate the valves, as well as the energies and the pressures (where possible) delivered by the pyrotechnic sources. Functional performance ranged widely among the designs. Blowby cannot be prevented by o-ring seals; metal-to-metal seals were effective. Functional margin was determined by dividing the energy delivered by the pyrotechnic sources in excess to that required to accomplish the function by the energy required for that function. All but two designs had adequate functional margins with the pyrotechnic cartridges evaluated.
Choice probability generating functions
Fosgerau, Mogens; McFadden, Daniel; Bierlaire, Michel
2010-01-01
This paper establishes that every random utility discrete choice model (RUM) has a representation that can be characterized by a choice-probability generating function (CPGF) with specific properties, and that every function with these specific properties is consistent with a RUM. The choice...... probabilities from the RUM are obtained from the gradient of the CPGF. Mixtures of RUM are characterized by logarithmic mixtures of their associated CPGF. The paper relates CPGF to multivariate extreme value distributions, and reviews and extends methods for constructing generating functions for applications...
Polysheroidal periodic functions
Separation of variables in the Helmholtz N-dimensional (N≥4) equation in polyspheroidal coordinate systems leads to the necessity of solving equations going over into equations for polyspheroidal periodic functions used for solving the two-centre problem in quantum mechanics, the three-body problem with Coulomb interaction, etc. For these functions the expansions are derived in terms of the Jacobi polynomials and Bessel functions. Their basic properties, asymptotics are considered. The algorithm of their computer calculations is developed. The results of numerical calculations are given
A Functional HAZOP Methodology
Liin, Netta; Lind, Morten; Jensen, Niels;
2010-01-01
functional HAZOP methodology lends itself directly for implementation into a computer aided reasoning tool to perform root cause and consequence analysis. Such a tool can facilitate finding causes and/or consequences far away from the site of the deviation. A functional HAZOP assistant is proposed and...... investigated in a HAZOP study of an industrial scale Indirect Vapor Recompression Distillation pilot Plant (IVaRDiP) at DTU-Chemical and Biochemical Engineering. The study shows that the functional HAZOP methodology provides a very efficient paradigm for facilitating HAZOP studies and for enabling reasoning to...
Longhi, Silvia; Radetti, Giorgio
2013-01-01
Nowadays, childhood obesity is one of the biggest health emergencies in the developed countries. Obesity leads to multiple metabolic alterations which increase the risk of developing diabetes and cardiovascular diseases. Thyroid function has been often described as altered in obese children, however, it is not clear whether the altered thyroid function is the cause or the consequence of fat excess. On the other hand, thyroid structure seems also to be affected. Nevertheless, both functional and structural alterations seem to improve after weight loss and therefore no treatment is needed. PMID:23149391
Gauravaram, Praveen; Knudsen, Lars Ramkilde
2010-01-01
value should not serve as an image for two distinct input messages and it should be difficult to find the input message from a given hash value. Secure hash functions serve data integrity, non-repudiation and authenticity of the source in conjunction with the digital signature schemes. Keyed hash...... functions, also called message authentication codes (MACs) serve data integrity and data origin authentication in the secret key setting. The building blocks of hash functions can be designed using block ciphers, modular arithmetic or from scratch. The design principles of the popular Merkle...
Bioprinting: Functional droplet networks
Durmus, Naside Gozde; Tasoglu, Savas; Demirci, Utkan
2013-06-01
Tissue-mimicking printed networks of droplets separated by lipid bilayers that can be functionalized with membrane proteins are able to spontaneously fold and transmit electrical currents along predefined paths.
... Spread the Word Shop AAP Find a Pediatrician Family Life Medical Home Family Dynamics Adoption & Foster Care ... Español Text Size Email Print Share Normal Functioning Family Page Content Article Body Is there any way ...
Center for Functional Nanomaterials
Federal Laboratory Consortium — The Center for Functional Nanomaterials (CFN) explores the unique properties of materials and processes at the nanoscale. The CFN is a user-oriented research center...
2011-01-01
This book reviews the results of recent research on new materials arising from progress in polymer, ceramic, sensor, and fuel cell technology, including advanced inorganic-organic-hybrid polymeric materials, high functional sensor, and microbial fuel cells.
Kellerstein, M; Verbaarschot, J J M
2016-01-01
The behavior of quenched Dirac spectra of two-dimensional lattice QCD is consistent with spontaneous chiral symmetry breaking which is forbidden according to the Coleman-Mermin-Wagner theorem. One possible resolution of this paradox is that, because of the bosonic determinant in the partially quenched partition function, the conditions of this theorem are violated allowing for spontaneous symmetry breaking in two dimensions or less. This goes back to work by Niedermaier and Seiler on nonamenable symmetries of the hyperbolic spin chain and earlier work by two of the auhtors on bosonic partition functions at nonzero chemical potential. In this talk we discuss chiral symmetry breaking for the bosonic partition function of QCD at nonzero isospin chemical potential and a bosonic random matrix theory at imaginary chemical potential and compare the results with the fermionic counterpart. In both cases the chiral symmetry group of the bosonic partition function is noncompact.
Pair Correlation Function Integrals
Wedberg, Nils Hejle Rasmus Ingemar; O'Connell, John P.; Peters, Günther H.J.;
2011-01-01
numerical tests complementing previous results. Pure molecular fluids are here studied in the isothermal-isobaric ensemble with isothermal compressibilities evaluated from the total correlation function integrals and compared with values derived from volume fluctuations. For systems where the radial...
Reasoning about Function Objects
Nordio, Martin; Calcagno, Cristiano; Meyer, Bertrand; Müller, Peter; Tschannen, Julian
Modern object-oriented languages support higher-order implementations through function objects such as delegates in C#, agents in Eiffel, or closures in Scala. Function objects bring a new level of abstraction to the object-oriented programming model, and require a comparable extension to specification and verification techniques. We introduce a verification methodology that extends function objects with auxiliary side-effect free (pure) methods to model logical artifacts: preconditions, postconditions and modifies clauses. These pure methods can be used to specify client code abstractly, that is, independently from specific instantiations of the function objects. To demonstrate the feasibility of our approach, we have implemented an automatic prover, which verifies several non-trivial examples.
N. Carella
2013-09-01
Full Text Available A new unconditional inequality of the totient function is contributed to the literature. This result is associated with various unsolved problems about the distribution of prime numbers.
Phonology in Axiomatic Functionalism
Bičan, Aleš
2009-01-01
Roč. 57, 1-2 (2009), s. 19-33. ISSN 1803-7410 Institutional research plan: CEZ:AV0Z90610518 Keywords : phonology * Axiomatic Functionalism * Mulder * phonematics * phonotactics * prosody Subject RIV: AI - Linguistics
... et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 25. Scanlon PD. Respiratory function: mechanisms and testing. In: Goldman ... 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap ...
Ghrelin and Functional Dyspepsia
Takashi Akamizu; Hiroshi Iwakura; Hiroyuki Ariyasu; Kenji Kangawa
2010-01-01
The majority of patients with dyspepsia have no identifiable cause of their disease, leading to a diagnosis of functional dyspepsia (FD). While a number of different factors affect gut activity, components of the nervous and endocrine systems are essential for normal gut function. Communication between the brain and gut occurs via direct neural connections or endocrine signaling events. Ghrelin, a peptide produced by the stomach, affects gastric motility/emptying and secretion, suggesting it ...
Green's functions with applications
Duffy, Dean G
2015-01-01
This second edition systematically leads readers through the process of developing Green's functions for ordinary and partial differential equations. In addition to exploring the classical problems involving the wave, heat, and Helmholtz equations, the book includes special sections on leaky modes, water waves, and absolute/convective instability. The book helps readers develop an intuition about the behavior of Green's functions, and considers the questions of the computational efficiency and possible methods for accelerating the process.
Production Functions Behaving Badly
Fredholm, Thomas
This paper reconsiders Anwar Shaikh's critique of the neoclassical theory of growth and distribution based on its use of aggregate production functions. This is done by reconstructing and extending Franklin M. Fisher's 1971 computer simulations, which Shaikh used to support his critique. Together...... with other recent extensions to Shaikh's seminal work, my results support and strengthen the evidence against the use of aggregate production functions....
Daniel A. Barone; Krieger, Ana C.
2015-01-01
The importance of sleep can be ascertained by noting the effects of its loss, which tends to be chronic and partial, on cognition, mood, alertness, and overall health. Many theories have been put forth to explain the function of sleep in humans, including proposals based on energy conservation, ecological adaptations, neurocognitive function, neural plasticity, nervous system and physical health, and performance. Most account for only a portion of sleep behavior and few are based on strong ex...
O'Farrell, Anthony G.
1991-01-01
Ever since the famous thesis of Frostman, capacities have been important in many areas of function theory. In this talk I shall be concerned only with one–variable function theory on arbitrary open subsets of the complex plane, C. It is important to stress that the open sets need not be connected. I will discuss the use of analytic capacities in connection with problems of removable singularities, holomorphic approximation, and boundary smoothness. A brief reference to the applications ...
Setare, M.R.(Department of Science, University of Kurdistan, Campus of Bijar, Bijar, Iran); Kamali, V.
2011-01-01
Boundary conformal field theory (BCFT) is the study of conformal field theory (CFT) on manifolds with a boundary. We can use conformal symmetry to constrain correlation functions of conformal invariant fields. We compute two-point and three-point functions of conformal invariant fields which live in semi-infinite space. For a situation with a boundary condition in surface $z=\\bar{z}$ ($t=0$), the results agree with gravity dual results. We also explore representations of conformal group in tw...
Service functional test automation
Hillah, Lom Messan; Maesano, Ariele-Paolo; Rosa, Fabio; Maesano, Libero; Lettere, Marco; Fontanelli, Riccardo
2015-01-01
This paper presents the automation of the functional test of services (black-box testing) and services architectures (grey-box testing) that has been developed by the MIDAS project and is accessible on the MIDAS SaaS. In particular, the paper illustrates the solutions of tough functional test automation problems such as: (i) the configuration of the automated test execution system against large and complex services architectures, (ii) the constraint-based test input generation, (iii) the spec...
Purely Functional Structured Programming
Obua, Steven
2010-01-01
The idea of functional programming has played a big role in shaping today's landscape of mainstream programming languages. Another concept that dominates the current programming style is Dijkstra's structured programming. Both concepts have been successfully married, for example in the programming language Scala. This paper proposes how the same can be achieved for structured programming and PURELY functional programming via the notion of LINEAR SCOPE. One advantage of this proposal is that m...
In this talk I summarize ideas and plans which have been put forward by members of all collaborations running muon or neutrino experiments at CERN. During our discussions there was general agreement that: i) substantial improvements of structure function measurements in the SPS range are still possible and necessary and ii) it is the responsibility of the present groups and of CERN to provide a ''final'' set of structure functions in the present energy range. (orig.)
Pancreatic Exocrine Function Testing
Goff, John S.
1982-01-01
It is important to understand which pancreatic function tests are available and how to interpret them when evaluating patients with malabsorption. Available direct tests are the secretin stimulation test, the Lundh test meal, and measurement of serum or fecal enzymes. Indirect tests assess pancreatic exocrine function by measuring the effect of pancreatic secretion on various nutrients. These include triglycerides labeled with carbon 14, cobalamin labeled with cobalt 57 and cobalt 58, and par...
Instance based function learning
Ramon, Jan; De Raedt, Luc
1999-01-01
The principles of instance based function learning are presented. In IBFL one is given a set of positive examples of a functional predicate. These examples are true ground facts that illustrate the input output behaviour of the predicate. The purpose is then to predict the output of the predicate given a new input. Further assumptions are that there is no background theory and that the inputs and outputs of the predicate consist of structured terms. IBFL is a novel technique that addresses th...
It is being argued that even in non-relativistic quantum mechanics the coordinate and momentum variables cannot be interpreted directly as observables. Only by defining these by suitable test bodies can we obtain verifiable predictions. When these arguments are implemented on a Wigner distribution it is shown that positive phase space probabilities always ensue, and hence this function can be used as a quantum mechanical phase space function. (author)
Griffel, DH
2002-01-01
A stimulating introductory text, this volume examines many important applications of functional analysis to mechanics, fluid mechanics, diffusive growth, and approximation. Detailed enough to impart a thorough understanding, the text is also sufficiently straightforward for those unfamiliar with abstract analysis. Its four-part treatment begins with distribution theory and discussions of Green's functions. Essentially independent of the preceding material, the second and third parts deal with Banach spaces, Hilbert space, spectral theory, and variational techniques. The final part outlines the
Pankaj Talwar; Suryakant Hayatnagarkar
2015-01-01
With absolute normal semen analysis parameters it may not be necessary to shift to specialized tests early but in cases with borderline parameters or with history of fertilization failure in past it becomes necessary to do a battery of tests to evaluate different parameters of spermatozoa. Various sperm function tests are proposed and endorsed by different researchers in addition to the routine evaluation of fertility. These tests detect function of a certain part of spermatozoon and give ins...
Handbook of functional equations functional inequalities
2014-01-01
As Richard Bellman has so elegantly stated at the Second International Conference on General Inequalities (Oberwolfach, 1978), “There are three reasons for the study of inequalities: practical, theoretical, and aesthetic.” On the aesthetic aspects, he said, “As has been pointed out, beauty is in the eye of the beholder. However, it is generally agreed that certain pieces of music, art, or mathematics are beautiful. There is an elegance to inequalities that makes them very attractive.” The content of the Handbook focuses mainly on both old and recent developments on approximate homomorphisms, on a relation between the Hardy–Hilbert and the Gabriel inequality, generalized Hardy–Hilbert type inequalities on multiple weighted Orlicz spaces, half-discrete Hilbert-type inequalities, on affine mappings, on contractive operators, on multiplicative Ostrowski and trapezoid inequalities, Ostrowski type inequalities for the Riemann–Stieltjes integral, means and related functional inequalities, Weighted G...
The Cosmological Time Function
Andersson, L; Howard, R
1998-01-01
Let $(M,g)$ be a time oriented Lorentzian manifold and $d$ the Lorentzian distance on $M$. The function $\\tau(q):=\\sup_{p< q} d(p,q)$ is the cosmological time function of $M$, where as usual $p< q$ means that $p$ is in the causal past of $q$. This function is called regular iff $\\tau(q) < \\infty$ for all $q$ and also $\\tau \\to 0$ along every past inextendible causal curve. If the cosmological time function $\\tau$ of a space time $(M,g)$ is regular it has several pleasant consequences: (1) It forces $(M,g)$ to be globally hyperbolic, (2) every point of $(M,g)$ can be connected to the initial singularity by a rest curve (i.e., a timelike geodesic ray that maximizes the distance to the singularity), (3) the function $\\tau$ is a time function in the usual sense, in particular (4) $\\tau$ is continuous, in fact locally Lipschitz and the second derivatives of $\\tau$ exist almost everywhere.
Space race functional responses.
Sjödin, Henrik; Brännström, Åke; Englund, Göran
2015-02-22
We derive functional responses under the assumption that predators and prey are engaged in a space race in which prey avoid patches with many predators and predators avoid patches with few or no prey. The resulting functional response models have a simple structure and include functions describing how the emigration of prey and predators depend on interspecific densities. As such, they provide a link between dispersal behaviours and community dynamics. The derived functional response is general but is here modelled in accordance with empirically documented emigration responses. We find that the prey emigration response to predators has stabilizing effects similar to that of the DeAngelis-Beddington functional response, and that the predator emigration response to prey has destabilizing effects similar to that of the Holling type II response. A stability criterion describing the net effect of the two emigration responses on a Lotka-Volterra predator-prey system is presented. The winner of the space race (i.e. whether predators or prey are favoured) is determined by the relationship between the slopes of the species' emigration responses. It is predicted that predators win the space race in poor habitats, where predator and prey densities are low, and that prey are more successful in richer habitats. PMID:25589602
Samson Z Assefa
2015-08-01
Full Text Available Sleep is a ubiquitous component of animal life including birds and mammals. The exact function of sleep has been one of the mysteries of biology. A considerable number of theories have been put forward to explain the reason(s for the necessity of sleep. To date, while a great deal is known about what happens when animals sleep, there is no definitive comprehensive explanation as to the reason that sleep is an inevitable part of animal functioning. It is well known that sleep is a homeostatically regulated body process, and that prolonged sleep deprivation is fatal in animals. In this paper, we present some of the theories as to the functions of sleep and provide a review of some hypotheses as to the overall physiologic function of sleep. To better understand the purpose for sleeping, we review the effects of sleep deprivation on physical, neurocognitive and psychic function. A better understanding of the purpose for sleeping will be a great advance in our understanding of the nature of the animal kingdom, including our own.
Talwar, Pankaj; Hayatnagarkar, Suryakant
2015-01-01
With absolute normal semen analysis parameters it may not be necessary to shift to specialized tests early but in cases with borderline parameters or with history of fertilization failure in past it becomes necessary to do a battery of tests to evaluate different parameters of spermatozoa. Various sperm function tests are proposed and endorsed by different researchers in addition to the routine evaluation of fertility. These tests detect function of a certain part of spermatozoon and give insight on the events in fertilization of the oocyte. The sperms need to get nutrition from the seminal plasma in the form of fructose and citrate (this can be assessed by fructose qualitative and quantitative estimation, citrate estimation). They should be protected from the bad effects of pus cells and reactive oxygen species (ROS) (leukocyte detection test, ROS estimation). Their number should be in sufficient in terms of (count), structure normal to be able to fertilize eggs (semen morphology). Sperms should have intact and functioning membrane to survive harsh environment of vagina and uterine fluids (vitality and hypo-osmotic swelling test), should have good mitochondrial function to be able to provide energy (mitochondrial activity index test). They should also have satisfactory acrosome function to be able to burrow a hole in zona pellucida (acrosome intactness test, zona penetration test). Finally, they should have properly packed DNA in the nucleus to be able to transfer the male genes (nuclear chromatic decondensation test) to the oocyte during fertilization. PMID:26157295
Pankaj Talwar
2015-01-01
Full Text Available With absolute normal semen analysis parameters it may not be necessary to shift to specialized tests early but in cases with borderline parameters or with history of fertilization failure in past it becomes necessary to do a battery of tests to evaluate different parameters of spermatozoa. Various sperm function tests are proposed and endorsed by different researchers in addition to the routine evaluation of fertility. These tests detect function of a certain part of spermatozoon and give insight on the events in fertilization of the oocyte. The sperms need to get nutrition from the seminal plasma in the form of fructose and citrate (this can be assessed by fructose qualitative and quantitative estimation, citrate estimation. They should be protected from the bad effects of pus cells and reactive oxygen species (ROS (leukocyte detection test, ROS estimation. Their number should be in sufficient in terms of (count, structure normal to be able to fertilize eggs (semen morphology. Sperms should have intact and functioning membrane to survive harsh environment of vagina and uterine fluids (vitality and hypo-osmotic swelling test, should have good mitochondrial function to be able to provide energy (mitochondrial activity index test. They should also have satisfactory acrosome function to be able to burrow a hole in zona pellucida (acrosome intactness test, zona penetration test. Finally, they should have properly packed DNA in the nucleus to be able to transfer the male genes (nuclear chromatic decondensation test to the oocyte during fertilization.
Renal Function in Hypothyroidism
Background hypothyroidism induces significant changes in the function of organ systems such as the heart, muscles and brain. Renal function is also influenced by thyroid status. Physiological effects include changes in water and electrolyte metabolism, notably hyponatraemia, and reliable alterations of renal hemodynamics, including decrements in renal blood flow, renal plasma flow, glomerular filtration rate (GFR). Objective renal function is profoundly influenced by thyroid status, the purpose of the present study was to determine the relationship between renal function and thyroid status of patients with hypothyroidism. Design and patients in 5 patients with primary hypothyroidism and control group renal functions are measured by serum creatinine and glomerular filtration rate(GFR) using modified in diet renal disease (MDRD) formula. Result in hypothyroidism, mean serum creatinine increased and mean estimated GFR decreased, compared to the control group mean serum creatinine decreased and mean estimated GFR increased. The hypothyroid patients showed elevated serum creatinine levels(>1.1 mg/d1) compared to control group (p value= 000). In patients mean estimated GFR increased in the control group (p value=.002).Conclusion thus the kidney, in addition to the brain, heart and muscle, is an important target of the action of thyroid hormones.(Author)
Renal Function in Hypothyroidism
Background Hypothyroidism induces significant changes in the function of organ systems such as the heart, muscles and brain. Renal function is also influenced by thyroid status. Physiological effects include changes in water and electrolyte metabolism, notably hyponatremia, and reliable alterations of renal hemodynamics, including decrements in renal blood flow, renal plasma flow, glomerular filtration rate (GFR). Objective Renal function is profoundly influenced by thyroid status; the purpose of the present study was to determine the relationship between renal function and thyroid status of patients with hypothyroidism. Design and Patients In 5 patients with primary hypothyroidism and control group renal functions are measured by serum creatinine and glomerular filtration rate (GFR) using modified in diet renal disease (MDRD) formula. Result In hypothyroidism, mean serum creatinine increased and mean estimated GFR decreased, compared to the control group mean serum creatinine decreased and mean estimated GFR Increased. The hypothyroid patients showed elevated serum creatinine levels (> 1.1mg/dl) compared to control group (p value .000). In patients mean estimated GFR decreased, compared to mean estimated GFR increased in the control group (p value= .002).
Protein Functionalized Nanodiamond Arrays
Liu YL
2010-01-01
Full Text Available Abstract Various nanoscale elements are currently being explored for bio-applications, such as in bio-images, bio-detection, and bio-sensors. Among them, nanodiamonds possess remarkable features such as low bio-cytotoxicity, good optical property in fluorescent and Raman spectra, and good photostability for bio-applications. In this work, we devise techniques to position functionalized nanodiamonds on self-assembled monolayer (SAMs arrays adsorbed on silicon and ITO substrates surface using electron beam lithography techniques. The nanodiamond arrays were functionalized with lysozyme to target a certain biomolecule or protein specifically. The optical properties of the nanodiamond-protein complex arrays were characterized by a high throughput confocal microscope. The synthesized nanodiamond-lysozyme complex arrays were found to still retain their functionality in interacting with E. coli.
Ghrelin and Functional Dyspepsia
Takashi Akamizu
2010-01-01
Full Text Available The majority of patients with dyspepsia have no identifiable cause of their disease, leading to a diagnosis of functional dyspepsia (FD. While a number of different factors affect gut activity, components of the nervous and endocrine systems are essential for normal gut function. Communication between the brain and gut occurs via direct neural connections or endocrine signaling events. Ghrelin, a peptide produced by the stomach, affects gastric motility/emptying and secretion, suggesting it may play a pathophysiological role in FD. It is also possible that the functional abnormalities in FD may affect ghrelin production in the stomach. Plasma ghrelin levels are reported to be altered in FD, correlating with FD symptom score. Furthermore, some patients with FD suffer from anorexia with body-weight loss. As ghrelin increases gastric emptying and promotes feeding, ghrelin therapy may be a new approach to the treatment of FD.
In this report a nucleon structure function analysis will be discussed. In CHORUS experiment, lead-scintillator calorimeter was used as active target and in 1998 run a high statistics sample of CC interactions of muon (anti-) neutrinos were collected. This sample was used to extract the structure functions of the nucleons in neutrino interactions. A Monte-Carlo program has been developed to study the efficiencies of the detector and for the proper corrections to be applied to the data. The structure functions, F1, F2, xF3, were extracted using three different kinds of fits. The effects of different systematic dependencies have also been studied. Results have been compared to the earlier experiments, CCFR and CDHSW
Algal functional annotation tool
Lopez, D. [UCLA; Casero, D. [UCLA; Cokus, S. J. [UCLA; Merchant, S. S. [UCLA; Pellegrini, M. [UCLA
2012-07-01
The Algal Functional Annotation Tool is a web-based comprehensive analysis suite integrating annotation data from several pathway, ontology, and protein family databases. The current version provides annotation for the model alga Chlamydomonas reinhardtii, and in the future will include additional genomes. The site allows users to interpret large gene lists by identifying associated functional terms, and their enrichment. Additionally, expression data for several experimental conditions were compiled and analyzed to provide an expression-based enrichment search. A tool to search for functionally-related genes based on gene expression across these conditions is also provided. Other features include dynamic visualization of genes on KEGG pathway maps and batch gene identifier conversion.
Nielsen, Line A.; Zois, Nora Elisabeth; Pedersen, Henrik D.;
2007-01-01
Background: Clinical studies investigating platelet function in dogs have had conflicting results that may be caused by normal physiologic variation in platelet response to agonists. Objectives: The objective of this study was to investigate platelet function in clinically healthy dogs of 4...... different breeds by whole-blood aggregometry and with a point-of-care platelet function analyzer (PFA-100), and to evaluate the effect of acetylsalicylic acid (ASA) administration on the results from both methods. Methods: Forty-five clinically healthy dogs (12 Cavalier King Charles Spaniels [CKCS], 12...... the methodology applied. However, the importance of these breed differences remains to be investigated. The PFA-100 method with Col + Epi as agonists, and ADP-induced platelet aggregation appear to be sensitive to ASA in dogs....
Spaces of continuous functions
Groenewegen, G L M
2016-01-01
The space C(X) of all continuous functions on a compact space X carries the structure of a normed vector space, an algebra and a lattice. On the one hand we study the relations between these structures and the topology of X, on the other hand we discuss a number of classical results according to which an algebra or a vector lattice can be represented as a C(X). Various applications of these theorems are given. Some attention is devoted to related theorems, e.g. the Stone Theorem for Boolean algebras and the Riesz Representation Theorem. The book is functional analytic in character. It does not presuppose much knowledge of functional analysis; it contains introductions into subjects such as the weak topology, vector lattices and (some) integration theory.
Quantal density functional theory
Sahni, Viraht
2016-01-01
This book deals with quantal density functional theory (QDFT) which is a time-dependent local effective potential theory of the electronic structure of matter. The treated time-independent QDFT constitutes a special case. In the 2nd edition, the theory is extended to include the presence of external magnetostatic fields. The theory is a description of matter based on the ‘quantal Newtonian’ first and second laws which is in terms of “classical” fields that pervade all space, and their quantal sources. The fields, which are explicitly defined, are separately representative of electron correlations due to the Pauli exclusion principle, Coulomb repulsion, correlation-kinetic, correlation-current-density, and correlation-magnetic effects. The book further describes Schrödinger theory from the new physical perspective of fields and quantal sources. It also describes traditional Hohenberg-Kohn-Sham DFT, and explains via QDFT the physics underlying the various energy functionals and functional derivatives o...
Functional Programming Using F#
Hansen, Michael Reichhardt; Rischel, Hans
. Coverage also includes advanced features in the .NET library, the imperative features of F# and topics such as text processing, sequences, computation expressions and asynchronous computation. With a broad spectrum of examples and exercises, the book is perfect for courses in functional programming......This comprehensive introduction to the principles of functional programming using F# shows how to apply basic theoretical concepts to produce succinct and elegant programs. It demonstrates the role of functional programming in a wide spectrum of applications including databases and systems...... and for self-study. Enhancing its use as a text is an accompanying website with downloadable programs, lecture slides, a mini-projects and links to further F# sources....
Dynamic function studies can be defined as a measure of the variation of a quantity of a substance in an organ with time. Such studies are clinically useful only when the underlying physiological model is realistic. Usually the measurements are of three kinds: the uptake function, the transit function and the removal function. Sensitivity of these measurements can be enhanced in several clinical situations by intervention, such as exercise or drugs. It is possible to display a nuclear image in a variety of ways through computer manipulations which are justified only if based on a valid physiological model. The newer radiopharmaceuticals have also increased the range of functions that can be studied, especially in the case of the heart and the brain. Positron emission tomography (PET) images are fascinating but they are prohibitively expensive and routine clinical nuclear medicine will have to rely on information obtained with single photon emission computer tomography (SPECT). In the diagnosis of cancer, the instrument alone would not improve the diagnosis. It is necessary to have radiopharmaceuticals with a high degree of specificity of uptake. This can possibly be achieved with immunoscintigraphy. There also, the kinetics of uptake of the labelled antibody enable one to differentiate specific from non-specific uptake. The need for good reliable dynamic function studies is as great in the developing as in the developed countries, but a nuclear medicine specialist in a developing country would need more skills and experience because of the heavy odds against which one would be working. (author). 43 refs, 2 figs
Chromatin Structure and Function
Wolffe, Alan P
1999-01-01
The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. The book is written in a clear and concise fashion, with 60 new illustrations. Chromatin: Structure and Function provides the reader with a concise and coherent account of the nature, structure, and assembly of chromatin and its active
Block, Ned
1996-01-01
What is Functionalism? Functionalism is one of the major proposals that have been offered as solutions to the mind/body problem. Solutions to the mind/body problem usually try to answer questions such as: What is the ultimate nature of the mental? At the most general level, what makes a mental state mental? Or more specifically, What do thoughts have in common in virtue of which they are thoughts? That is, what makes a thought a thought? What makes a pain a pain? Cartesian Dualism said the ul...
Bech-Larsen, Tino; Scholderer, Joachim
2007-01-01
The fact that the European markets for functional foods generally are less developed, compared to the US and the Japanese markets, has often been attributed to a restrictive and inconsistent health claim legislation in and between the European countries. With the European Parliament's second...... reading of the main principles of the harmonized regulation COM/2003/0424, this situation is about to change. This article reviews the regulatory aspects, the results of consumer research and the marketing strategies regarding the use of health claims for functional foods in Europe, and it comments on the...
Gómez-Romero, Pedro; Sanchez, Clément
2004-04-01
Functional Hybrid Materials consist of both organic and inorganic components, assembled for the purpose of generating desirable properties and functionalities. The aim is twofold: to bring out or enhance advantageous chemical, electrochemical, magnetic or electronic characteristics and at the same time to reduce or wholly suppress undesirable properties or effects. Another target is the creation of entirely new material behavior. The vast number of hybrid material components available has opened up a wide and diversified field of fascinating research. In this book, a team of highly renowned experts gives an in-depth overview, illustrating the superiority of well-designed hybrid materials and their potential applications.
Neurally augmented sexual function.
Meloy, S
2007-01-01
Neurally Augmented Sexual Function (NASF) is a technique utilizing epidural electrodes to restore and improve sexual function. Orgasmic dysfunction is common in adult women, affecting roughly one quarter of populations studied. Many male patients suffering from erectile dysfunction are not candidates for phosphdiesterase therapy due to concomitant nitrate therapy. Positioning the electrodes at roughly the level of the cauda equina allows for stimulation of somatic efferents and afferents as well as modifying sympathetic and parasympathetic activity. Our series of women treated by NASF is described. Our experience shows that the evaluation of potential candidates for both correctable causes and psychological screening are important considerations. PMID:17691397
Algal functional annotation tool
2012-07-12
Abstract BACKGROUND: Progress in genome sequencing is proceeding at an exponential pace, and several new algal genomes are becoming available every year. One of the challenges facing the community is the association of protein sequences encoded in the genomes with biological function. While most genome assembly projects generate annotations for predicted protein sequences, they are usually limited and integrate functional terms from a limited number of databases. Another challenge is the use of annotations to interpret large lists of 'interesting' genes generated by genome-scale datasets. Previously, these gene lists had to be analyzed across several independent biological databases, often on a gene-by-gene basis. In contrast, several annotation databases, such as DAVID, integrate data from multiple functional databases and reveal underlying biological themes of large gene lists. While several such databases have been constructed for animals, none is currently available for the study of algae. Due to renewed interest in algae as potential sources of biofuels and the emergence of multiple algal genome sequences, a significant need has arisen for such a database to process the growing compendiums of algal genomic data. DESCRIPTION: The Algal Functional Annotation Tool is a web-based comprehensive analysis suite integrating annotation data from several pathway, ontology, and protein family databases. The current version provides annotation for the model alga Chlamydomonas reinhardtii, and in the future will include additional genomes. The site allows users to interpret large gene lists by identifying associated functional terms, and their enrichment. Additionally, expression data for several experimental conditions were compiled and analyzed to provide an expression-based enrichment search. A tool to search for functionally-related genes based on gene expression across these conditions is also provided. Other features include dynamic visualization of genes
Characterisation of Functional Surfaces
Lonardo, P.M.; De Chiffre, Leonardo; Bruzzone, A.A.
2004-01-01
Characterisation of surfaces is of fundamental importance to control the manufacturing process and the functional performance of the part. Many applications concern contact and tribology problems, which include friction, wear and lubrication. This paper presents the techniques and instruments for...... characterisation of surfaces, discussing their operating principles and metrological properties. A review of the conventional 2D and new 3D roughness parameters is given, considering both the current standards and new proposals for texture quantification, with a particular attention to the methods orientated...... towards a functional characterisation of surfaces....
Harmonic supergraphs. Green functions
The quantization procedure in the harmonic superspace approach is worked out. Harmonic distributions are introduced and are used to construct the analytic superspace delta-functions and the Green functions for the hypermultiplet and the N=2 Yang-Mills superfields. The gauge fixing is described and the relevant Faddeev-Popov ghosts are defined. The corresponding BRST transformations are found. The harmonic superspace quantization of the N=2 gauge theory turns out to be rather simple and has many parallels with that for the standard (N=0) Yang-Mills theory. In particular, no ghosts-forghosts are needed
GADRAS Detector Response Function.
Mitchell, Dean J.; Harding, Lee; Thoreson, Gregory G; Horne, Steven M.
2014-11-01
The Gamma Detector Response and Analysis Software (GADRAS) applies a Detector Response Function (DRF) to compute the output of gamma-ray and neutron detectors when they are exposed to radiation sources. The DRF is fundamental to the ability to perform forward calculations (i.e., computation of the response of a detector to a known source), as well as the ability to analyze spectra to deduce the types and quantities of radioactive material to which the detectors are exposed. This document describes how gamma-ray spectra are computed and the significance of response function parameters that define characteristics of particular detectors.
Rarefied elliptic hypergeometric functions
Spiridonov, V P
2016-01-01
We prove exact evaluation formulae for two multiple rarefied elliptic beta integrals related to the simplest lens space. These integrals generalize the multiple type I and II van Diejen-Spiridonov integrals attached to the root system $C_n$. Symmetries of the rarefied elliptic analogue of the Euler-Gauss hypergeometric function are described and the corresponding generalization of the hypergeometric equation is constructed. An extension of the latter function to the root system $C_n$ and applications to some eigenvalue problems are briefly discussed.
Compositional Belief Function Models
Jiroušek, Radim
Nagoya : Nagoya University , 2008, s. 1311-1316. ISSN 1880-3741. [Joint 4th International Conference on Soft Computing and Intelligent systems and 9th International Symposium on Advanced Intelligent Systems. Nagoya (JP), 17.09.2008-21.09.2008] R&D Projects: GA MŠk 1M0572 Grant ostatní: GA MŠk(CZ) 2C06019 Institutional research plan: CEZ:AV0Z10750506 Keywords : compositional model * belief function * multidimensionality Subject RIV: IN - Informatics, Computer Science http://library.utia.cas.cz/separaty/2008/MTR/jirousek-compositional belief function models.pdf
无
2001-01-01
@@ Genomics is a biology term appeared ten years ago, used to describe the researches of genomic mapping, sequencing, and structure analysis, etc. Genomics, the first journal for publishing papers on genomics research was born in 1986. In the past decade, the concept of genomics has been widely accepted by scientists who are engaging in biology research. Meanwhile, the research scope of genomics has been extended continuously, from simple gene mapping and sequencing to function genomics study. To reflect the change, genomics is divided into two parts now, the structure genomics and the function genomics.
Holographic Three point Functions
Bissi, Agnese
In this thesis it is addressed the problem of the computation of three point correlation functions within the AdS=CFT correspondence. In the context of the AdS 5=CFT4 correspondence we present three computations. First we compare the results of tree level three point functions of two giant...... gravitons and a point like graviton and its dual counterpart, namely two Schur polynomials and a single trace chiral primary. Secondly we compute the one loop correction to planar, non extremal three point functions of two heavy and one light operators, both from the gauge and string side in the Frolov......-Tseytlin regime. Finally we generalize the scalar product of two states belonging to the SO(6) sector of N = 4 SYM with implications on the construction of three point functions of 3 non-BPS operators from the gauge theory side. On the other hand in the AdS4=CFT3 correspondence we compare the computations in the...
Holographic Three point Functions
Martirosyan, Ara
The main subject of this thesis is the computation of structure constants appearing in the three-point functions for certain type of states/operators in the context of the AdS/CFT correspondence, which is one of the important parts of the dynamical problem in the dual theories of the correspondence...
Functional ingredients from microalgae
Buono, S.; Langellotti, A.L.; Martello, A.; Rinna, F.; Fogliano, V.
2014-01-01
A wide variety of natural sources are under investigation to evaluate their possible use for new functional ingredient formulation. Some records attested the traditional and ancient use of wild harvested microalgae as human food but their cultivation for different purposes started about 40 years ago
Laboratory Density Functionals
Giraud, B. G.
2007-01-01
We compare several definitions of the density of a self-bound system, such as a nucleus, in relation with its center-of-mass zero-point motion. A trivial deconvolution relates the internal density to the density defined in the laboratory frame. This result is useful for the practical definition of density functionals.
Müller, Vladimír
Basel : Springer, 2015 - (Alpay, D.), s. 1181-1215 ISBN 978-3-0348-0666-4 Institutional support: RVO:67985840 Keywords : Taylor spectrum * Taylor functional calculus * split spectrum Subject RIV: BA - General Mathematics http://link.springer.com/referenceworkentry/10.1007/978-3-0348-0667-1_61
Deimling, Klaus
1985-01-01
topics. However, only a modest preliminary knowledge is needed. In the first chapter, where we introduce an important topological concept, the so-called topological degree for continuous maps from subsets ofRn into Rn, you need not know anything about functional analysis. Starting with Chapter 2, where infinite dimensions first appear, one should be familiar with the essential step of consider ing a sequence or a function of some sort as a point in the corresponding vector space of all such sequences or functions, whenever this abstraction is worthwhile. One should also work out the things which are proved in § 7 and accept certain basic principles of linear functional analysis quoted there for easier references, until they are applied in later chapters. In other words, even the 'completely linear' sections which we have included for your convenience serve only as a vehicle for progress in nonlinearity. Another point that makes the text introductory is the use of an essentially uniform mathematical languag...
Objectification and Semiotic Function
Santi, George
2011-01-01
The objective of this paper is to study students' difficulties when they have to ascribe the same meaning to different representations of the same mathematical object. We address two theoretical tools that are at the core of Radford's cultural semiotic and Godino's onto-semiotic approaches: objectification and the semiotic function. The analysis…
Empirical microeconomics action functionals
Baaquie, Belal E.; Du, Xin; Tanputraman, Winson
2015-06-01
A statistical generalization of microeconomics has been made in Baaquie (2013), where the market price of every traded commodity, at each instant of time, is considered to be an independent random variable. The dynamics of commodity market prices is modeled by an action functional-and the focus of this paper is to empirically determine the action functionals for different commodities. The correlation functions of the model are defined using a Feynman path integral. The model is calibrated using the unequal time correlation of the market commodity prices as well as their cubic and quartic moments using a perturbation expansion. The consistency of the perturbation expansion is verified by a numerical evaluation of the path integral. Nine commodities drawn from the energy, metal and grain sectors are studied and their market behavior is described by the model to an accuracy of over 90% using only six parameters. The paper empirically establishes the existence of the action functional for commodity prices that was postulated to exist in Baaquie (2013).
Bibliography of Axiomatic Functionalism
Bičan, Aleš
Bern : Peter Lang, 2011 - (Bičan, A.; Rastall, P.), s. 289-304 ISBN 978-3-0343-1033-8 R&D Projects: GA MŠk(CZ) LC546 Institutional research plan: CEZ:AV0Z90610518 Keywords : axiomatic * functionalism * bibliography Subject RIV: AI - Linguistics
Automatic Functional Harmonic Analysis
de Haas, W.B.; Magalhães, J.P.; Wiering, F.; Veltkamp, R.C.
2013-01-01
Music scholars have been studying tonal harmony intensively for centuries, yielding numerous theories and models. Unfortunately, a large number of these theories are formulated in a rather informal fashion and lack mathematical precision. In this article we present HarmTrace, a functional model of W
Conjugate flow action functionals
We present a new general framework to construct an action functional for a non-potential field theory. The key idea relies on representing the governing equations relative to a diffeomorphic flow of curvilinear coordinates which is assumed to be functionally dependent on the solution field. Such flow, which will be called the conjugate flow, evolves in space and time similarly to a physical fluid flow of classical mechanics and it can be selected in order to symmetrize the Gâteaux derivative of the field equations with respect to suitable local bilinear forms. This is equivalent to requiring that the governing equations of the field theory can be derived from a principle of stationary action on a Lie group manifold. By using a general operator framework, we obtain the determining equations of such manifold and the corresponding conjugate flow action functional. In particular, we study scalar and vector field theories governed by second-order nonlinear partial differential equations. The identification of transformation groups leaving the conjugate flow action functional invariant could lead to the discovery of new conservation laws in fluid dynamics and other disciplines
Safety System functional inspections
The basic purpose of Safety System Functional Inspections (SSFI) is to carry out an impartial and independent assessment of previously selected safety systems, in order to determine whether they have been installed, tested, operated and managed in accordance with the original Design Bases and with the applicable regulatory requirements, codes and standards, that is, their Licensing Bases. These functional inspections are performed within the framework established by the Quality Assurance Programmes of electric utility owners, and in accordance with specifically prepared procedures previously approved for each power plant. These SSFIs verify, for safety systems and their support systems (eg HVAC systems, etc), the operational availability of inspected systems of components by researching and determining whether there have been generic or programmed deficiencies in the course of Operation, that will prevent the systems from adequately performing the functions for which they were originally designed. PSA and IPE results are used as the basis for selecting the systems that should undergo functional inspections. As a consequence of these SSFIs, final reports will be prepared, summarizing actions taken at the plants and contemplating discrepancies or deviations detected during inspection. The necessary corrective actions for these discrepancies will be indicated in either the design documentation or the Operation and Maintenance Procedures. (Author)
Functional Maximum Autocorrelation Factors
Larsen, Rasmus; Nielsen, Allan Aasbjerg
2005-01-01
\\verb+~+\\$\\backslash\\$cite{ramsay97} to functional maximum autocorrelation factors (MAF)\\verb+~+\\$\\backslash\\$cite{switzer85,larsen2001d}. We apply the method to biological shapes as well as reflectance spectra. {\\$\\backslash\\$bf Methods}. MAF seeks linear combination of the original variables that maximize autocorrelation between...
Bayes Multiple Decision Functions
Wu, Wensong
2011-01-01
This paper deals with the problem of simultaneously making many (M) binary decisions based on one realization of a random data matrix X. M is typically large and X will usually have M rows associated with each of the M decisions to make, but for each row the data may be low dimensional. A Bayesian decision-theoretic approach for this problem is implemented with the overall loss function being a cost-weighted linear combination of Type I and Type II loss functions. The class of loss functions considered allows for the use of the false discovery rate (FDR), false nondiscovery rate (FNR), and missed discovery rate (MDR) in assessing the decision. Through this Bayesian paradigm, the Bayes multiple decision function (BMDF) is derived and an efficient algorithm to obtain the optimal Bayes action is described. In contrast to many works in the literature where the rows of the matrix X are assumed to be stochastically independent, we allow in this paper a dependent data structure with the associations obtained through...
On Dupree's resonance function
It is shown that Dupree's resonance function has a negative real asymptotic tail, so that the dispersion relation of the renormalized weak turbulence theory leads to unstable high phase velocity waves, even when the average distribution is a Gaussian. A possible explanation of this paradox is proposed
Cobham recursive set functions
Beckmann, A.; Buss, S.; Friedman, S.-D.; Müller, M.; Thapen, Neil
2016-01-01
Roč. 167, č. 3 (2016), s. 335-369. ISSN 0168-0072 R&D Projects: GA ČR GBP202/12/G061 Institutional support: RVO:67985840 Keywords : set function * polynomial time * Cobham recursion Subject RIV: BA - General Mathematics Impact factor: 0.548, year: 2014 http://www.sciencedirect.com/science/article/pii/S0168007215001293
... nerve injury, or brain damage ( stroke or other brain injury) The loss of muscle function after these types of events can be severe. Often it will not completely return, even with treatment. Paralysis can be temporary or permanent. It can affect ...
Biggs, William D.
1987-01-01
Defines computerized functional business games as those focusing on decision making and integration in the areas of accounting/finance, marketing, personnel/human resources, and production/operations. Nine currently available games are reviewed and evaluated in the context of a learning model. (Author/LRW)
Brants, T; Krenn, B; Brants, Thorsten; Skut, Wojciech; Krenn, Brigitte
1997-01-01
This paper addresses issues in automated treebank construction. We show how standard part-of-speech tagging techniques extend to the more general problem of structural annotation, especially for determining grammatical functions and syntactic categories. Annotation is viewed as an interactive process where manual and automatic processing alternate. Efficiency and accuracy results are presented. We also discuss further automation steps.
Modifiable Combining Functions
Cohen, Paul; Shafer, Glenn; Shenoy, Prakash P.
2013-01-01
Modifiable combining functions are a synthesis of two common approaches to combining evidence. They offer many of the advantages of these approaches and avoid some disadvantages. Because they facilitate the acquisition, representation, explanation, and modification of knowledge about combinations of evidence, they are proposed as a tool for knowledge engineers who build systems that reason under uncertainty, not as a normative theory of evidence.
Gaming and "Functional Democracy".
Goodman, F. L.
An example of the way gaming can be used to bring attention to, and improve skills in, making democracy function better is presented. The game is played by seven people seated around two triangular playing boards; it involves making choices among least, intermediate, and most preferred alternatives, keeping the preferences of the majority in…
Ramesh Kalindri
2014-06-01
Full Text Available Currently, software engineers are increasingly turning to the option of automating functional tests, but not always have successful in this endeavor. Reasons range from low planning until over cost in the process. Some principles that can guide teams in automating these tests are described in this article.
Skew quasisymmetric Schur functions and noncommutative Schur functions
Bessenrodt, Christine; van Willigenburg, Stephanie
2010-01-01
Recently a new basis for the Hopf algebra of quasisymmetric functions $QSym$, called quasisymmetric Schur functions, has been introduced by Haglund, Luoto, Mason, van Willigenburg. In this paper we extend the definition of quasisymmetric Schur functions to introduce skew quasisymmetric Schur functions. These functions include both classical skew Schur functions and quasisymmetric Schur functions as examples, and give rise to a new poset $\\mathcal{L}_C$ that is analogous to Young's lattice. We also introduce a new basis for the Hopf algebra of noncommutative symmetric functions $NSym$. This basis of $NSym$ is dual to the basis of quasisymmetric Schur functions and its elements are the pre-image of the Schur functions under the forgetful map $\\chi: NSym \\rightarrow Sym$. We prove that the multiplicative structure constants of the noncommutative Schur functions, equivalently the coefficients of the skew quasisymmetric Schur functions when expanded in the quasisymmetric Schur basis, are nonnegative integers, sati...
Stability of Trigonometric Functional Equations in Generalized Functions
Chung Jaeyoung
2010-01-01
Full Text Available We consider the Hyers-Ulam stability of a class of trigonometric functional equations in the spaces of generalized functions such as Schwartz distributions, Fourier hyperfunctions, and Gelfand generalized functions.
EXECUTIVE FUNCTIONING IN SCHIZOPHRENIA
Gricel eOrellana
2013-06-01
Full Text Available The executive function (EF is a set of abilities, which allows us to invoke voluntary control of our behavioral responses. These functions enable human beings to develop and carry out plans, make up analogies, obey social rules, solve problems, adapt to unexpected circumstances, do many tasks simultaneously and locate episodes in time and place. EF includes divided attention and sustained attention, working memory, set-shifting, flexibility, planning and the regulation of goal directed behavior and can be defined as a brain function underlying the human faculty to act or think not only in reaction to external events but also in relation with internal goals and states. EF is mostly associated with dorsolateral prefrontal cortex (PFC. Besides EF, PFC is involved in self-regulation of behavior, i.e. the ability to regulate behavior according to internal goals and constraints, particularly in less structured situations. Self-regulation of behavior is subtended by ventral medial /orbital PFC. Impairment of EF is one of the most commonly observed deficits in schizophrenia through the various disease stages. Impairment in tasks measuring conceptualization, planning, cognitive flexibility, verbal fluency, ability to solve complex problems and working memory occur in schizophrenia. Disorders detected by executive tests are consistent with evidence from functional neuroimaging, which have shown PFC dysfunction in patients while performing these kinds of tasks. Schizophrenics also exhibit deficit in odor identifying, decision-making and self-regulation of behavior suggesting dysfunction of the orbital PFC. However, impairment in executive tests is explained by dysfunction of prefronto-striato-thalamic, prefronto-parietal and prefronto-temporal neural networks mainly. Disorders in executive functions may be considered central facts with respect to schizophrenia and it has been suggested that negative symptoms may be explained by that executive dysfunction.
Partition density functional theory
Nafziger, Jonathan
Partition density functional theory (PDFT) is a method for dividing a molecular electronic structure calculation into fragment calculations. The molecular density and energy corresponding to Kohn Sham density-functional theory (KS-DFT) may be exactly recovered from these fragments. Each fragment acts as an isolated system except for the influence of a global one-body 'partition' potential which deforms the fragment densities. In this work, the developments of PDFT are put into the context of other fragment-based density functional methods. We developed three numerical implementations of PDFT: One within the NWChem computational chemistry package using basis sets, and the other two developed from scratch using real-space grids. It is shown that all three of these programs can exactly reproduce a KS-DFT calculation via fragment calculations. The first of our in-house codes handles non-interacting electrons in arbitrary one-dimensional potentials with any number of fragments. This code is used to explore how the exact partition potential changes for different partitionings of the same system and also to study features which determine which systems yield non-integer PDFT occupations and which systems are locked into integer PDFT occupations. The second in-house code, CADMium, performs real-space calculations of diatomic molecules. Features of the exact partition potential are studied for a variety of cases and an analytical formula determining singularities in the partition potential is derived. We introduce an approximation for the non-additive kinetic energy and show how this quantity can be computed exactly. Finally a PDFT functional is developed to address the issues of static correlation and delocalization errors in approximations within DFT. The functional is applied to the dissociation of H2 + and H2.
West, J. B.; Elliott, A. R.; Guy, H. J.; Prisk, G. K.
1997-01-01
The lung is exquisitely sensitive to gravity, and so it is of interest to know how its function is altered in the weightlessness of space. Studies on National Aeronautics and Space Administration (NASA) Spacelabs during the last 4 years have provided the first comprehensive data on the extensive changes in pulmonary function that occur in sustained microgravity. Measurements of pulmonary function were made on astronauts during space shuttle flights lasting 9 and 14 days and were compared with extensive ground-based measurements before and after the flights. Compared with preflight measurements, cardiac output increased by 18% during space flight, and stroke volume increased by 46%. Paradoxically, the increase in stroke volume occurred in the face of reductions in central venous pressure and circulating blood volume. Diffusing capacity increased by 28%, and the increase in the diffusing capacity of the alveolar membrane was unexpectedly large based on findings in normal gravity. The change in the alveolar membrane may reflect the effects of uniform filling of the pulmonary capillary bed. Distributions of blood flow and ventilation throughout the lung were more uniform in space, but some unevenness remained, indicating the importance of nongravitational factors. A surprising finding was that airway closing volume was approximately the same in microgravity and in normal gravity, emphasizing the importance of mechanical properties of the airways in determining whether they close. Residual volume was unexpectedly reduced by 18% in microgravity, possibly because of uniform alveolar expansion. The findings indicate that pulmonary function is greatly altered in microgravity, but none of the changes observed so far will apparently limit long-term space flight. In addition, the data help to clarify how gravity affects pulmonary function in the normal gravity environment on Earth.
Functional equations for zeta functions of groups and rings
Voll, Christopher
2010-01-01
We introduce a new method to compute explicit formulae for various zeta functions associated to groups and rings. The specific form of these formulae enables us to deduce local functional equations. More precisely, we prove local functional equations for the subring zeta functions associated to rings, the subgroup, conjugacy and representation zeta functions of finitely generated, torsion-free nilpotent (or $\\T$-)groups, and the normal zeta functions of $\\T$-groups of class 2. In particular w...
Functional equations for local normal zeta functions of nilpotent groups
Voll, Christopher
2003-01-01
We give explicit formulae for the local normal zeta functions of torsion-free, class-2-nilpotent groups, subject to conditions on the associated Pfaffian hypersurface which are generically satisfied by groups with small centre and sufficiently large abelianization. We show how the functional equations of two types of zeta functions - the Weil zeta function associated to an algebraic variety and zeta functions of algebraic groups introduced by Igusa - match up to give a functional equation for...
Comparisons of power transfer functions and flow transfer functions
Transfer functions may be used to calculate component feedbacks or temperature increments by convolution of the transfer function with the appropriate fractional change in system-quantity. Power-change transfer functions have been reported. The corresponding flow transfer functions for this case, and comparison with the power transfer functions, are reported here. Results of feedback simulation of ramped flow transients using flow transfer functions are also described
Uniqueness property for quasiharmonic functions
Sevdiyor A. Imomkulov
2014-10-01
Full Text Available In this paper we consider a class of continuous functions, called quasiaharmonic functions, admitting best approximations by harmonic polynomials. In this class we prove a uniqueness theorem by analogy with the analytic functions.
Quasi-extended asymptotic functions
The class F of ''quasi-extended asymptotic functions'' is introduced. It contains all extended asymptotic functions as well as some new asymptotic functions very similar to the Schwartz distributions. On the other hand, every two quasiextended asymptotic functions can be multiplied as opposed to the Schwartz distributions; in particular, the square delta2 of an asymptotic function delta similar to Dirac's delta-function, is constructed as an example
Operator Algebras of Functions
Mittal, Meghna
2009-01-01
We present some general theorems about operator algebras that are algebras of functions on sets, including theories of local algebras, residually finite dimensional operator algebras and algebras that can be represented as the scalar multipliers of a vector-valued reproducing kernel Hilbert space. We use these to further develop a quantized function theory for various domains that extends and unifies Agler's theory of commuting contractions and the Arveson-Drury-Popescu theory of commuting row contractions. We obtain analogous factorization theorems, prove that the algebras that we obtain are dual operator algebras and show that for many domains, supremums over all commuting tuples of operators satisfying certain inequalities are obtained over all commuting tuples of matrices.
Functionalization of Carbon Nanotubes
Khare, Bishun N. (Inventor); Meyyappan, Meyya (Inventor)
2009-01-01
Method and system for functionalizing a collection of carbon nanotubes (CNTs). A selected precursor gas (e.g., H2 or F2 or CnHm) is irradiated to provide a cold plasma of selected target species particles, such as atomic H or F, in a first chamber. The target species particles are d irected toward an array of CNTs located in a second chamber while suppressing transport of ultraviolet radiation to the second chamber. A CNT array is functionalized with the target species particles, at or below room temperature, to a point of saturation, in an exposure time interval no longer than about 30 sec. *Discrimination against non-target species is provided by (i) use of a target species having a lifetime that is much greater than a lifetime of a non-target species and/or (2) use of an applied magnetic field to discriminate between charged particle trajectories for target species and for non-target species.
Process for functionalizing alkanes
Bergman, R.G.; Janowicz, A.H.; Periana-Pillai, R.A.
1984-06-12
Process for functionalizing saturated hydrocarbons selectively in the terminal position comprises: (a) reacting said saturated hydrocarbons with a metal complex CpRhPMe/sub 3/H/sub 2/ in the presence of ultraviolet radiation at -60/sup 0/ to -17/sup 0/C to form a hydridoalkyl complex CpRhPMe/sub 3/RH; (b) reacting said hydridoalkyl complex with a haloform CHX/sub 3/ at -60/sup 0/ to -17/sup 0/C to form the corresponding haloalkyl complex of step (a) CpRhPMe/sub 3/RX; and (c) reacting said haloalkyl complex with halogen -60 to 25/sup 0/C to form a functional haloalkyl compound.
Sørensen, A S; Hansen, H; Høgenhaven, H;
1988-01-01
Two groups of epilepsy patients (28 patients with temporal lobe epilepsy and 15 patients with primary generalized epilepsy) entered a study of personality traits related to epilepsy, based on a modification of Bellak's semistructured interview for assessment of ego strength. Two groups of subjects...... served as controls: 15 patients with a non-neurological but relapsing disorder, psoriasis, and 15 healthy volunteers. Compared with the group of healthy volunteers, a decreased adaptive level of ego functioning was found in the epilepsy groups, regardless of seizure types and EEG findings, and, to a...... than 15 years when the disease began. The number of anticonvulsants administered did not influence the results. No difference on adaptive level of ego functioning was found between the group with primary generalized epilepsy and the group with temporal lobe epilepsy. Similarly, the temporal lobe...
Daniel A. Barone
2015-06-01
Full Text Available The importance of sleep can be ascertained by noting the effects of its loss, which tends to be chronic and partial, on cognition, mood, alertness, and overall health. Many theories have been put forth to explain the function of sleep in humans, including proposals based on energy conservation, ecological adaptations, neurocognitive function, neural plasticity, nervous system and physical health, and performance. Most account for only a portion of sleep behavior and few are based on strong experimental support. In this review, we present theories proposing why sleep is necessary and supporting data demonstrating the effects of inadequate sleep, with the intention of gleaning further information as to its necessity, which remains one of the most perplexing mysteries in biology.
This volume is based on a series of lectures delivered at a one-day teaching symposium on functional and metabolic aspects of NMR measurements held at the Middlesex Hospital Medical School on 1st September 1985 as a part of the European Nuclear Medicine Society Congress. Currently the major emphasis in medical NMR in vivo is on its potential to image and display abnormalities in conventional radiological images, providing increased contrast between normal and abnormal tissue, improved definition of vasculature, and possibly an increased potential for differential diagnosis. Although these areas are undeniably of major importance, it is probable that NMR will continue to complement conventional measurement methods. The major potential benefits to be derived from in vivo NMR measurements are likely to arise from its use as an instrument for functional and metabolic studies in both clinical research and in the everyday management of patients. It is to this area that this volume is directed
Larsen, S H; Wagner, G; Heitmann, B L
2007-01-01
OBJECTIVE: To review the literature on the relationship between obesity and sexual function. METHOD: A search in the medical literature from 1966 and onwards was carried out through Medline and Embase for publications on obesity, in combination with Medical Subject Heading words related to sexual...... function and dysfunction. COMMENTS: Four prospective and seven cross-sectional studies were found describing association between obesity and erectile dysfunction (ED). One cross-sectional study was found describing obesity and female sexual dysfunction (FSD). The prospective studies on ED all demonstrated...... sexual activity among both men and women after weight loss intervention. CONCLUSION: Support for the assumption that obesity is associated with ED was found in both prospective and cross-sectional studies. FSD was not adequately described in the literature and prospective studies are needed here. Results...
Pancreatic exocrine function testing
It is important to understand which pancreatic function tests are available and how to interpret them when evaluating patients with malabsorption. Available direct tests are the secretin stimulation test, the Lundh test meal, and measurement of serum or fecal enzymes. Indirect tests assess pancreatic exocrine function by measuring the effect of pancreatic secretion on various nutrients. These include triglycerides labeled with carbon 14, cobalamin labeled with cobalt 57 and cobalt 58, and para-aminobenzoic acid bound to a dipeptide. Of all these tests the secretin stimulation test is the most accurate and reliable if done by experienced personnel. However, the indirect tests are simpler to do and appear to be comparable to the secretin test at detecting pancreatic exocrine insufficiency. These indirect tests are becoming clinically available and clinicians should familiarize themselves with the strengths and weaknesses of each
VEZURE OANA SABINA
2011-09-01
Full Text Available The emergence of public finances is due to objective causes needs and determined their main function being to obtain the financial resources it needs for the State to exercise its powers and on the way to intervene in the economy and society general. Public finances are necessary, subjectively and objectively, as it contributes to accomplishing the tasks and functions of the state, which could not be realized without financial leverage. Public finances are inextricably linked to the existence of the state, and public sector's role in the economy. Thus, they express "social relations, economic arising in the establishment and use of public funds between the state, on the one hand, and members of society on the other hand, to meet the needs of general interest of society" [1]. Thus, the role of public finance is to meet the needs of general interest or collective needs.
Nuclear Parton Distribution Functions
I. Schienbein, J.Y. Yu, C. Keppel, J.G. Morfin, F. Olness, J.F. Owens
2009-06-01
We study nuclear effects of charged current deep inelastic neutrino-iron scattering in the framework of a {chi}{sup 2} analysis of parton distribution functions (PDFs). We extract a set of iron PDFs which are used to compute x{sub Bj}-dependent and Q{sup 2}-dependent nuclear correction factors for iron structure functions which are required in global analyses of free nucleon PDFs. We compare our results with nuclear correction factors from neutrino-nucleus scattering models and correction factors for charged-lepton--iron scattering. We find that, except for very high x{sub Bj}, our correction factors differ in both shape and magnitude from the correction factors of the models and charged-lepton scattering.
Morselli, Lisa L.; Guyon, Aurore; Spiegel, Karine
2011-01-01
Evidence for the role of sleep on metabolic and endocrine function has been reported more than four decades ago. In the past 30 years, the prevalence of obesity and diabetes has greatly increased in industrialized countries, and self-imposed sleep curtailment, now very common, is starting to be recognized as a contributing factor, alongside with increased caloric intake and decreased physical activity. Furthermore, obstructive sleep apnea, a chronic condition characterized by recurrent upper ...
Ontogenesis of Myocardial Function
Sedmera, David; Ošťádal, Bohuslav
New York: Springer, 2012 - (Sedmera, D.; Wang, T.), s. 147-175 ISBN 978-1-4614-3386-6 R&D Projects: GA MŠk(CZ) 1M0510; GA ČR(CZ) GA304/08/0615; GA ČR(CZ) GAP302/11/1308 Institutional research plan: CEZ:AV0Z50110509 Institutional support: RVO:67985823 Keywords : embryo * cardiovascular function * morphogenesis Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
Generalised twisted partition functions
Petkova, V B
2001-01-01
We consider the set of partition functions that result from the insertion of twist operators compatible with conformal invariance in a given 2D Conformal Field Theory (CFT). A consistency equation, which gives a classification of twists, is written and solved in particular cases. This generalises old results on twisted torus boundary conditions, gives a physical interpretation of Ocneanu's algebraic construction, and might offer a new route to the study of properties of CFT.
Godbole, Rohini M.(Centre for High Energy Physics, Indian Institute of Science, 560012, Bangalore, India)
1996-01-01
After briefly explaining the idea of photon structure functions (F gamma2, F gammaL),I review the current theoretical and experimental developements in the subject of extraction of q-gamma from a study of the Deep Inelastic Scattering (DIS). I then end by pointing out recent progress in getting information about the parton content of the photon from hard processes other than DIS.
Lang, E E
2010-06-01
Vestibular symptoms of vertigo, dizziness and dysequilibrium are common complaints which can be disabling both physically and psychologically. Routine examination of the ear nose and throat and neurological system are often normal in these patients. An accurate history and thorough clinical examination can provide a diagnosis in the majority of patients. However, in a subgroup of patients, vestibular function testing may be invaluable in arriving at a correct diagnosis and ultimately in the optimal treatment of these patients.
Gunn, Teresa M.
2012-01-01
Functional annotation of every gene in the mouse genome is a herculean task that requires a multifaceted approach. Many large-scale initiatives are contributing to this undertaking. The International Knockout Mouse Consortium (IKMC) plans to mutate every protein-coding gene, using a combination of gene trapping and gene targeting in embryonic stem cells. Many other groups are performing using the chemical mutagen ethylnitrosourea (ENU) or transpon-based systems to induce mutations, screening ...
Choice Probability Generating Functions
Fosgerau, Mogens; McFadden, Daniel L; Bierlaire, Michel
This paper considers discrete choice, with choice probabilities coming from maximization of preferences from a random utility field perturbed by additive location shifters (ARUM). Any ARUM can be characterized by a choice-probability generating function (CPGF) whose gradient gives the choice...... probabilities, and every CPGF is consistent with an ARUM. We relate CPGF to multivariate extreme value distributions, and review and extend methods for constructing CPGF for applications....
Generalized Network Externality Function
A. Paothong; G.S. Ladde
2012-01-01
In this work, we focus on the development of mathematical modeling of network externality processes. The introduction of the generalized network externality function provides a unified source of a tool for developing and analyzing the planning, policy and performance of the network externality process and network goods/services in a systematic way. This leads to fulfill all existing network externality assumptions as special cases. We study its properties and applications. This study provides...
Reserve Function in Enterprise
Agnieszka Duraj
2003-01-01
Reserves occupy an important place and play a big part at the enterprise.s financial management system. Problem of reserves also belongs to principle matter of strategic management.they expresses through creating the enterprises competitive position. Reserves fulfill many of various functions in the enterprises. Reserves permit to avoid the risk accompanying the economic activity of each enterprise; they create to the firm a chance of effective development and opportunities of protection of o...
Parametric contest success functions
Birendra K. Rai1; Sarin, Rajiv
2007-01-01
The key element of models of contest is the Contest Success Function (CSF) which specifies the winning probabilities of agents. We provide an axiomatization of two parametric families of CSFâ€™s. In the first, the winning probability of each agent depends on the investments and a vector of parameters, where each parameter is specific to one of the contestants. In the second, the winning probabilities depend on investments and a scalar parameter common to all contestants.
Generalized contest success functions
Birendra K. Rai1; Sarin, Rajiv
2007-01-01
The key element of models of contest is the Contest Success Function (CSF) which specifies the winning probabilities of agents. The existing axiomatizations of CSFs assume that contestants can make only one type of investment. This paper generalizes these axiomatizations to the case where each agent can have multiple types of investments. This allows us to provide a unified framework to extend and interpret the results of Skaperdas (1996) and Clark and Riis (1998), and rationalize some seemin...
Multiple correlation function approach
Grebenkov, Denis S.
2016-01-01
The multiple correlation function approach is briefly presented and applied to investigate spin-echo signal attenuation due to restricted diffusion in simple geometries (slab, cylinder, and sphere) in the presence of surface relaxation. Exact and explicit representations for the zeroth and second moments of the total phase accumulated by diffusing spins are derived by using the Laplace transform summation technique. Within the Gaussian phrase approximation, these two moments determine the ...
DIHYDRODIPYRIDOPYRAZINES: SYNTHESIS AND FUNCTIONALIZATION
Gérald Guillaumet
2010-04-01
Full Text Available Different conceptual synthetic approaches to the elaboration of a new family of planar polynuclear nitrogen containing aromatic heterocycles – the dihydrodipyridopyrazines – are reviewed: the arynic reaction, the sequence palladium coupling reaction - substitution - reduction - cyclization - substitution or through the intermediacy of Smiles rearrangement. Further functionalization of these compounds by substitution reaction, metalation sequence and palladium-catalyzed coupling reaction are also discussed.
Super Fractal Interpolation Functions
G. P. Kapoor; Prasad, Srijanani Anurag
2012-01-01
In the present work, the notion of Super Fractal Interpolation Function (SFIF) is introduced for finer simulation of the objects of the nature or outcomes of scientific experiments that reveal one or more structures embedded in to another. In the construction of SFIF, an IFS is chosen from a pool of several IFS at each level of iteration leading to implementation of the desired randomness and variability in fractal interpolation of the given data. Further, an expository description of our inv...
Daniel, Milan
Hradec Králové: Gaudeamus, 2015, s. 34-44. ISBN 978-80-7435-579-0. [Czech-Japan Seminar on Data Analysis and Decision Making under Uncertainty /18./. Broumov (CZ), 19.09.2015-22.09.2015] Institutional support: RVO:67985807 Keywords : belief function * theory of evidence * Dempster-Shafer theory * Dempster’s semigroup Subject RIV: BA - General Mathematics http://edu.uhk.cz/CJS2015/CJS_2015_Proceedings.pdf
Automated functional software testing
Jelnikar, Kristina
2009-01-01
The following work describes an approach to software test automation of functional testing. In the introductory part we are introducing what testing problems development companies are facing. The second chapter describes some testing methods, what role does testing have in software development, some approaches to software development and the meaning of testing environment. Chapter 3 is all about test automation. After a brief historical presentation, we are demonstrating through s...
Executive functioning in schizophrenia.
Orellana, Gricel; Slachevsky, Andrea
2013-01-01
The executive function (EF) is a set of abilities, which allows us to invoke voluntary control of our behavioral responses. These functions enable human beings to develop and carry out plans, make up analogies, obey social rules, solve problems, adapt to unexpected circumstances, do many tasks simultaneously, and locate episodes in time and place. EF includes divided attention and sustained attention, working memory (WM), set-shifting, flexibility, planning, and the regulation of goal directed behavior and can be defined as a brain function underlying the human faculty to act or think not only in reaction to external events but also in relation with internal goals and states. EF is mostly associated with dorsolateral prefrontal cortex (PFC). Besides EF, PFC is involved in self-regulation of behavior, i.e., the ability to regulate behavior according to internal goals and constraints, particularly in less structured situations. Self-regulation of behavior is subtended by ventral medial/orbital PFC. Impairment of EF is one of the most commonly observed deficits in schizophrenia through the various disease stages. Impairment in tasks measuring conceptualization, planning, cognitive flexibility, verbal fluency, ability to solve complex problems, and WM occur in schizophrenia. Disorders detected by executive tests are consistent with evidence from functional neuroimaging, which have shown PFC dysfunction in patients while performing these kinds of tasks. Schizophrenics also exhibit deficit in odor identifying, decision-making, and self-regulation of behavior suggesting dysfunction of the orbital PFC. However, impairment in executive tests is explained by dysfunction of prefronto-striato-thalamic, prefronto-parietal, and prefronto-temporal neural networks mainly. Disorders in EFs may be considered central facts with respect to schizophrenia and it has been suggested that negative symptoms may be explained by that executive dysfunction. PMID:23805107
Analyzing Pseudophosphatase Function.
Hinton, Shantá D
2016-01-01
Pseudophosphatases regulate signal transduction cascades, but their mechanisms of action remain enigmatic. Reflecting this mystery, the prototypical pseudophosphatase STYX (phospho-serine-threonine/tyrosine-binding protein) was named with allusion to the river of the dead in Greek mythology to emphasize that these molecules are "dead" phosphatases. Although proteins with STYX domains do not catalyze dephosphorylation, this in no way precludes their having other functions as integral elements of signaling networks. Thus, understanding their roles in signaling pathways may mark them as potential novel drug targets. This chapter outlines common strategies used to characterize the functions of pseudophosphatases, using as an example MK-STYX [mitogen-activated protein kinase (MAPK) phospho-serine-threonine/tyrosine binding], which has been linked to tumorigenesis, apoptosis, and neuronal differentiation. We start with the importance of "restoring" (when possible) phosphatase activity in a pseudophosphatase so that the active mutant may be used as a comparison control throughout immunoprecipitation and mass spectrometry analyses. To this end, we provide protocols for site-directed mutagenesis, mammalian cell transfection, co-immunoprecipitation, phosphatase activity assays, and immunoblotting that we have used to investigate MK-STYX and the active mutant MK-STYXactive. We also highlight the importance of utilizing RNA interference (RNAi) "knockdown" technology to determine a cellular phenotype in various cell lines. Therefore, we outline our protocols for introducing short hairpin RNA (shRNA) expression plasmids into mammalians cells and quantifying knockdown of gene expression with real-time quantitative PCR (qPCR). A combination of cellular, molecular, biochemical, and proteomic techniques has served as powerful tools in identifying novel functions of the pseudophosphatase MK-STYX. Likewise, the information provided here should be a helpful guide to elucidating the
Oden, J Tinsley
2010-01-01
The textbook is designed to drive a crash course for beginning graduate students majoring in something besides mathematics, introducing mathematical foundations that lead to classical results in functional analysis. More specifically, Oden and Demkowicz want to prepare students to learn the variational theory of partial differential equations, distributions, and Sobolev spaces and numerical analysis with an emphasis on finite element methods. The 1996 first edition has been used in a rather intensive two-semester course. -Book News, June 2010
Automatic Functional Harmonic Analysis
de Haas, W.B.; Magalhães, J.P.; Wiering, F.; Veltkamp, R.C.
2013-01-01
Music scholars have been studying tonal harmony intensively for centuries, yielding numerous theories and models. Unfortunately, a large number of these theories are formulated in a rather informal fashion and lack mathematical precision. In this article we present HarmTrace, a functional model of Western tonal harmony that builds on well-known theories of tonal harmony. In contrast to other approaches that remain purely theoretical, we present an implemented system that is evaluated empirica...
Mitochondria and Endothelial Function
Kluge, Matthew A.; Fetterman, Jessica L.; Vita, Joseph A.
2013-01-01
In contrast to their role in other cell types with higher energy demands, mitochondria in endothelial cells primarily function in signaling cellular responses to environmental cues. This article provides an overview of key aspects of mitochondrial biology in endothelial cells, including subcellular location, biogenesis, dynamics, autophagy, ROS production and signaling, calcium homeostasis, regulated cell death, and heme biosynthesis. In each section, we introduce key concepts and then review...
Green, L
1998-01-01
We often think of law as fulfilling certain social functions; for instance, it is said to guide behaviour, maintain order, settle disputes, and provide benefits and services. In the social sciences, more general claims are also made that law stabilizes the dominant mode of production, promotes economic efficiency, secures patriarchy, and so on. 1 What do these claims mean, and what do they contribute to our understanding of law as a social institution? Those are the questions I want to explor...
Physically Functional Materials
Berg, Rolf Henrik; Hvilsted, Søren; Ramanujam, P.S.
2002-01-01
The invention relates to novel monodisperse or polydisperse compounds, in general named DNO (diamino acid Nalpha-substituted oligopeptides), preferably low molecular weight polypeptides, e.g., based on ornithine, lysine, diaminobutyric acid, diaminopropionic acid, aminoethylglycine or other amino acids or peptides having azobenzenes or other physicially functional groups, e.g., photoresponsive groups, as side chains. These compounds may be synthesized using solid phase peptide synthesis techn...
Transporting Functions across Ornaments
Pierre-Evariste, Dagand
2012-01-01
Programming with dependent types is a blessing and a curse. It is a blessing to be able to bake invariants into the definition of data-types: we can finally write correct-by-construction software. However, this extreme accuracy is also a curse: a data-type is the combination of a structuring medium together with a special purpose logic. These domain-specific logics hamper any effort of code reuse among similarly structured data. In this paper, we exorcise our data-types by adapting the notion of ornament to our universe of inductive families. We then show how code reuse can be achieved by ornamenting functions. Using these functional ornament, we capture the relationship between functions such as the addition of natural numbers and the concatenation of lists. With this knowledge, we demonstrate how the implementation of the former informs the implementation of the latter: the user can ask the definition of addition to be lifted to lists and she will only be asked the details necessary to carry on adding lists...
Lymphocyte Functions in Microgravity
Pellis, Neal R.; Risin, Diane; Sundaresan, A.; Cooper, D.; Dawson, David L. (Technical Monitor)
1999-01-01
To understand the mechanism of immunity impairment in space it is important to analyze the direct effects of space-related conditions on different lymphocytes functions. Since 1992, we are investigating the effect of modeled and true microgravity (MG) on numerous lymphocyte functions. We had shown that modeled (MMG) and true microgravity inhibit lymphocyte locomotion through type I collagen. Modeled microgravity also suppresses polyclonal and antigen-specific lymphocyte activation. Polyclonal activation of lymphocytes prior to exposure to MMG abrogates the MG-induced inhibition of lymphocyte locomotion. The relationship between activation deficits and the loss of locomotion in MG was investigated using PKC activation by phorbol ester (PMA) and calcium ionophore (ionomycin). Direct activation of PKC by PMA substantially restored the MMG-inhibited lymphocyte locomotion and PHA-induced lymphocyte activation lonomycin by itself did not restore either locomotion or activation of the lymphocytes, indicating that these changes are not related to the impairment in the calcium flux in MMG. Treatment of lymphocytes with PMA before exposure to MMG prevented the loss of locomotion. It was observed that DNA synthesis is not necessary for restoration of locomotion since mitomicin C treated and untreated cells recovered their locomotion to the same level after PKC activation. Our recent data indicate that microgravity may selectively effect the expression of novel Ca2+ independent isoforms of PKC, in particularly PKC sigma and delta. This provides a new insight in understanding of the mechanisms of MG-sensitive cellular functions.
FUNCTIONAL MECHANISMS OF PROBIOTICS
Bijender Kumar Bajaj
2015-02-01
Full Text Available Probiotics are the live microorganisms which when ingested in adequate amounts confer health benefits. The strains most frequently used as probiotics include Lactic acid bacteria, bifidobacteria and yeast Saccharomyces boulardii. However, several other bacterial strains are being investigated for potential probiotic value viz. Enterococcus, Streptococcus, Bacillus, among others. Significant therapeutic potential of probiotics has been demonstrated in several in vitro studies and that involving animal models and humans. Despite intense focus on probiotics research the mechanisms responsible for health benefits are not yet completely understood. Several important mechanisms have been proposed such as improvement of gut epithelial barrier function, Immunomodulatory effects, degradation of toxin receptors, competition for nutrients, production of inhibitory substances, antiproliferative effects, blocking of adhesion sites and modulation of gut microbiota. Bacterial cell components such as DNA or peptidoglycan may also be involved in functional mechanism of probiotics. Effectiveness of a probiotic for potential application as prophylactic or treatment agent for certain ailment is determined by its ability to possess all or most of these characteristic features. The current article describes the general functional mechanisms of probiotics.
Magnetic static response functions
The response of a normally non-magnetic material to an external static magnetic field can be monitored by many different magnetic response functions. A general scheme to supply a corresponding theoretical description is presented that is based on the relativistic Korringa-Kohn-Rostoker Green function method of band structure calculations, and for that reason has many appealing features. First of all, it treats all spin as well as orbital contributions to the induced magnetization on the same footing, accounting in particular for all relativistic influences. Furthermore, it is extremely flexible and applicable in principle to any kind of system. Finally, a formulation for any response function can be worked out on this platform in a rather straightforward way. This is demonstrated together with corresponding applications for the magnetic form factor, the magnetic susceptibility and the Knight shift. In addition, a description of the so-called field-induced magnetic circular dichroism in x-ray absorption will be presented. In particular, it is shown that this new magneto-optical effect supplies a rather unique probe, giving information separately on the spin and orbital susceptibility in an element-resolved way
[Visuospatial functions and prematurity].
Miranda-Herrero, M C; Pascual-Pascual, S I; Barredo-Valderrama, E; Vazquez-Lopez, M; de Castro-De Castro, P
2014-11-01
Visuospatial functions are very important in learning process and development of abstract thought during childhood. Several studies show that preterm and low birth weight infants obtain lower scores in test that assess cognitive functions, specially in the first year of life. These differences are attenuated over time, but a developmental delay that affects working memory and visuospatial process still persists. It is unclear what factors are involved in development of these functions, and pre- or perinatal factors may interfere with the proper conduct of the same, but have been described anatomical and physiological differences between the preterm and term brain that could explain somewhere in these alterations. The different selective vulnerability to hypoxia between immature brain in which preoligodendrocytes and subplate neurons predominate, and mature brain, determine differences in the pattern of injury from hypoxia with greater involvement of the periventricular white matter in preterm children. This lesional pattern leaves to a dysfunction in attentional and visuospatial process, due to the increased vulnerability of the regions involved in the dorsal pathway of visual processing. PMID:25342055
Nicotinamide and neurocognitive function.
Rennie, George; Chen, Andrew C; Dhillon, Haryana; Vardy, Janette; Damian, Diona L
2015-07-01
Nicotinamide, or vitamin B3, is a precursor of nicotinamide adenine dinucleotide (NAD(+)) and is involved in a multitude of intra- and inter-cellular processes, which regulate some of the cell's metabolic, stress, and immune responses to physiological or pathological signals. As a precursor of NAD(+), which is a key coenzyme in the production of adenosine triphosphate or cellular energy, nicotinamide has been investigated for potential neuroprotective effects in cellular, animal, and human studies. Objectives We aimed to summarize the current evidence on the effect of dietary and supplemental nicotinamide on cognitive function. Methods A literature review was conducted on the effects of nicotinamide and its derivatives as a preventive and therapeutic agent for disorders of neurocognitive function. Specific conditions examined include age-related cognitive decline, Alzheimer's disease, Parkinson's disease, and ischaemic and traumatic brain injury. Results Data from animal and human interventional studies and epidemiological research suggests that nicotinamide may be beneficial in preserving and enhancing neurocognitive function. Discussion Nicotinamide is non-toxic, inexpensive and widely available, and interventional studies in humans, using supplemental doses of nicotinamide, are now warranted. PMID:24559077
Functions of Multivector Variables
Chappell, James M.; Iqbal, Azhar; Gunn, Lachlan J.; Abbott, Derek
2015-01-01
As is well known, the common elementary functions defined over the real numbers can be generalized to act not only over the complex number field but also over the skew (non-commuting) field of the quaternions. In this paper, we detail a number of elementary functions extended to act over the skew field of Clifford multivectors, in both two and three dimensions. Complex numbers, quaternions and Cartesian vectors can be described by the various components within a Clifford multivector and from our results we are able to demonstrate new inter-relationships between these algebraic systems. One key relationship that we discover is that a complex number raised to a vector power produces a quaternion thus combining these systems within a single equation. We also find a single formula that produces the square root, amplitude and inverse of a multivector over one, two and three dimensions. Finally, comparing the functions over different dimension we observe that Cℓ(ℜ3) provides a particularly versatile algebraic framework. PMID:25774689
Functional magnetic resonance imaging.
Buchbinder, Bradley R
2016-01-01
Functional magnetic resonance imaging (fMRI) maps the spatiotemporal distribution of neural activity in the brain under varying cognitive conditions. Since its inception in 1991, blood oxygen level-dependent (BOLD) fMRI has rapidly become a vital methodology in basic and applied neuroscience research. In the clinical realm, it has become an established tool for presurgical functional brain mapping. This chapter has three principal aims. First, we review key physiologic, biophysical, and methodologic principles that underlie BOLD fMRI, regardless of its particular area of application. These principles inform a nuanced interpretation of the BOLD fMRI signal, along with its neurophysiologic significance and pitfalls. Second, we illustrate the clinical application of task-based fMRI to presurgical motor, language, and memory mapping in patients with lesions near eloquent brain areas. Integration of BOLD fMRI and diffusion tensor white-matter tractography provides a road map for presurgical planning and intraoperative navigation that helps to maximize the extent of lesion resection while minimizing the risk of postoperative neurologic deficits. Finally, we highlight several basic principles of resting-state fMRI and its emerging translational clinical applications. Resting-state fMRI represents an important paradigm shift, focusing attention on functional connectivity within intrinsic cognitive networks. PMID:27432660
Kidney function decline and physical function in women
Lin, Julie; Curhan, Gary C.
2008-01-01
Background. Cross-sectional analyses of kidney function and physical function have identified profound quality of life impairments in people with advanced kidney dysfunction. No data are currently available, however, on how kidney function decline may be associated with physical function.
Collision-resistant hash function based on composition of functions
Ndoundam, Rene
2011-01-01
cryptographic hash function is a deterministic procedure that compresses an arbitrary block of numerical data and returns a fixed-size bit string. There exist many hash functions: MD5, HAVAL, SHA, ... It was reported that these hash functions are not longer secure. Our work is focused in the construction of a new hash function based on composition of functions. The construction used the NP-completeness of Three-dimensional contingency tables and the relaxation of the constraint that a hash function should also be a compression function.
Strange functions in real analysis
Kharazishvili, AB
2005-01-01
Weierstrass and Blancmange nowhere differentiable functions, Lebesgue integrable functions with everywhere divergent Fourier series, and various nonintegrable Lebesgue measurable functions. While dubbed strange or "pathological," these functions are ubiquitous throughout mathematics and play an important role in analysis, not only as counterexamples of seemingly true and natural statements, but also to stimulate and inspire the further development of real analysis.Strange Functions in Real Analysis explores a number of important examples and constructions of pathological functions. After introducing the basic concepts, the author begins with Cantor and Peano-type functions, then moves to functions whose constructions require essentially noneffective methods. These include functions without the Baire property, functions associated with a Hamel basis of the real line, and Sierpinski-Zygmund functions that are discontinuous on each subset of the real line having the cardinality continuum. Finally, he considers e...
Indefinite theta functions and black hole partition functions
We explore various aspects of supersymmetric black hole partition functions in four-dimensional toroidally compactified heterotic string theory. These functions suffer from divergences owing to the hyperbolic nature of the charge lattice in this theory, which prevents them from having well-defined modular transformation properties. In order to rectify this, we regularize these functions by converting the divergent series into indefinite theta functions, thereby obtaining fully regulated single-centered black hole partitions functions
Indefinite theta functions and black hole partition functions
Cardoso, Gabriel Lopes; Cirafici, Michele [Center for Mathematical Analysis, Geometry, and Dynamical Systems,Departamento de Matemática and LARSyS, Instituto Superior Técnico,1049-001 Lisboa (Portugal); Jorge, Rogério [Instituto Superior Técnico,1049-001 Lisboa (Portugal); Nampuri, Suresh [Laboratoire de Physique Théorique, École Normale Supérieure,24 rue Lhomond, 75231 Paris Cedex 05 (France)
2014-02-05
We explore various aspects of supersymmetric black hole partition functions in four-dimensional toroidally compactified heterotic string theory. These functions suffer from divergences owing to the hyperbolic nature of the charge lattice in this theory, which prevents them from having well-defined modular transformation properties. In order to rectify this, we regularize these functions by converting the divergent series into indefinite theta functions, thereby obtaining fully regulated single-centered black hole partitions functions.
NEUROFEEDBACK USING FUNCTIONAL SPECTROSCOPY.
Hinds, Oliver; Wighton, Paul; Tisdall, M Dylan; Hess, Aaron; Breiter, Hans; van der Kouwe, André
2014-06-01
Neurofeedback based on real-time measurement of the blood oxygenation level-dependent (BOLD) signal has potential for treatment of neurological disorders and behavioral enhancement. Commonly employed methods are based on functional magnetic resonance imaging (fMRI) sequences that sacrifice speed and accuracy for whole-brain coverage, which is unnecessary in most applications. We present multi-voxel functional spectroscopy (MVFS): a system for computing the BOLD signal from multiple volumes of interest (VOI) in real-time that improves speed and accuracy of neurofeedback. MVFS consists of a functional spectroscopy (FS) pulse sequence, a BOLD reconstruction component, a neural activation estimator, and a stimulus system. The FS pulse sequence is a single-voxel, magnetic resonance spectroscopy sequence without water suppression that has been extended to allow acquisition of a different VOI at each repetition and real-time subject head motion compensation. The BOLD reconstruction component determines the T2* decay rate, which is directly related to BOLD signal strength. The neural activation estimator discounts nuisance signals and scales the activation relative to the amount of ROI noise. Finally, the neurofeedback system presents neural activation-dependent stimuli to experimental subjects with an overall delay of less than 1s. Here we present the MVFS system, validation of certain components, examples of its usage in a practical application, and a direct comparison of FS and echo-planar imaging BOLD measurements. We conclude that in the context of realtime BOLD imaging, MVFS can provide superior accuracy and temporal resolution compared with standard fMRI methods. PMID:24999293
Bioinspired, functional nanoscale materials
Jun, In-Kook
Functional nanomaterials in nature exhibit many unique functions and optical and mechanical properties. Examples of this include the dry adhesion of a gecko's foot, the reduced drag on a shark's skin, the high strength and toughness of nacre, and the superhydrophobic self-cleaning of a lotus leaf. This dissertation is devoted to creating unique and enhanced properties by mimicking such functional materials. We have developed a novel self-pumping membrane, which does not require an applied voltage. The self-pumping membrane harvests chemical energy from a surrounding fluid and uses it for accelerated mass transport across the membrane. A device such as this has promising applications in implantable or remotely operating autonomous devices and membrane-based purification systems. Reproducible and highly active surface enhanced Raman scattering (SERS) substrates were developed using a bottom-up self-assembly technology. With their high sensitivity and good reproducibility, the developed nanostructures (gold nanoparticle and nanohole arrays) as SERS substrates are very promising for applications such as ultra-sensitive detectors for chemicals and reproducible sensors for chemical and biological molecules. Binary colloidal crystals were created using a simple, fast, and scalable spin-coating technology. Although further investigation of the procedure is needed to improve the ordering of particles in the individual layers, the developed assembly technology has a promising outlook in applications such as optical integrated circuits and high-speed optical computing. Inorganic-organic nanocomposites were realized by assembling synthesized gibbsite nanoplatelets using the electrophoretic deposition and infiltration of a monomer followed by polymerization. Via surface modifications of gibbsite nanoplatelets, nanocomposites were further reinforced with covalent linkages between the inorganic platelets and organic matrix.
Housset, Chantal; Chrétien, Yues; Debray, Dominique; Chignard, Nicolas
2016-01-01
The gallbladder stores and concentrates bile between meals. Gallbladder motor function is regulated by bile acids via the membrane bile acid receptor, TGR5, and by neurohormonal signals linked to digestion, for example, cholecystokinin and FGF15/19 intestinal hormones, which trigger gallbladder emptying and refilling, respectively. The cycle of gallbladder filling and emptying controls the flow of bile into the intestine and thereby the enterohepatic circulation of bile acids. The gallbladder also largely contributes to the regulation of bile composition by unique absorptive and secretory capacities. The gallbladder epithelium secretes bicarbonate and mucins, which both provide cytoprotection against bile acids. The reversal of fluid transport from absorption to secretion occurs together with bicarbonate secretion after feeding, predominantly in response to an adenosine 3',5'-cyclic monophosphate (cAMP)-dependent pathway triggered by neurohormonal factors, such as vasoactive intestinal peptide. Mucin secretion in the gallbladder is stimulated predominantly by calcium-dependent pathways that are activated by ATP present in bile, and bile acids. The gallbladder epithelium has the capacity to absorb cholesterol and provides a cholecystohepatic shunt pathway for bile acids. Changes in gallbladder motor function not only can contribute to gallstone disease, but also subserve protective functions in multiple pathological settings through the sequestration of bile acids and changes in the bile acid composition. Cholecystectomy increases the enterohepatic recirculation rates of bile acids leading to metabolic effects and an increased risk of nonalcoholic fatty liver disease, cirrhosis, and small-intestine carcinoid, independently of cholelithiasis. Among subjects with gallstones, cholecystectomy remains a priority in those at risk of gallbladder cancer, while others could benefit from gallbladder-preserving strategies. © 2016 American Physiological Society. Compr Physiol
Choice probability generating functions
Fosgerau, Mogens; McFadden, Daniel; Bierlaire, Michel
2013-01-01
This paper considers discrete choice, with choice probabilities coming from maximization of preferences from a random utility field perturbed by additive location shifters (ARUM). Any ARUM can be characterized by a choice-probability generating function (CPGF) whose gradient gives the choice...... probabilities, and every CPGF is consistent with an ARUM. We relate CPGF to multivariate extreme value distributions, and review and extend methods for constructing CPGF for applications. The choice probabilities of any ARUM may be approximated by a cross-nested logit model. The results for ARUM are extended to...
Effective and rigorous controls over highly enriched uranium and plutonium, the essential ingredients of nuclear weapons, are critical if we are to reduce nuclear arms, bring a halt to nuclear proliferation, and to avoid large-scale nuclear violence. Currently an unfortunate and simplistic 'one-size-fits-all' attitude about nuclear security is prominent. We have identified seven basic and decidedly distinct nuclear husbandry functions. The analysis leads to some predictions for effective nuclear arms control and nonproliferation, including the idea that domestic nuclear security and safeguards personnel, hardware, approaches, and auditing techniques are not automatically applicable to international arms control efforts. (author)
Bang, Anne Louise
2007-01-01
approaches will be developed and carried out with he intention to involve specific stakeholders within an industrial value chain in the design process. More specifically this paper reports on a pilot experiment initiated to explore if repertory grid models could be a way to investigate tactile and visual...... sensing of fabrics in function. It is proposed that tactile and visual sensing of fabrics is a way to investigate and express emotional utility values. The further purpose is to use experiments with repertory grid models as part of the mapping of the entire research project and also as a basis for...
Gelfand, I M; Shnol, E E
2002-01-01
The second in a series of systematic studies by a celebrated mathematician I. M. Gelfand and colleagues, this volume presents students with a well-illustrated sequence of problems and exercises designed to illuminate the properties of functions and graphs. Since readers do not have the benefit of a blackboard on which a teacher constructs a graph, the authors abandoned the customary use of diagrams in which only the final form of the graph appears; instead, the book's margins feature step-by-step diagrams for the complete construction of each graph. The first part of the book employs simple fu
Functional and Operatorial Statistics
Dabo-niang, Sophie
2008-01-01
An increasing number of statistical problems and methods involve infinite-dimensional aspects. This is due to the progress of technologies which allow us to store more and more information while modern instruments are able to collect data much more effectively due to their increasingly sophisticated design. This evolution directly concerns statisticians, who have to propose new methodologies while taking into account such high-dimensional data (e.g. continuous processes, functional data, etc.). The numerous applications (micro-arrays, paleo- ecological data, radar waveforms, spectrometric curv