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Sample records for adjustment disorder epidemiology

  1. Adjustment disorder

    American Psychiatric Association. Diagnostic and statistical manual of mental disorders . 5th ed. Arlington, VA: American Psychiatric Publishing. 2013. Powell AD. Grief, bereavement, and adjustment disorders. In: Stern TA, Fava ...

  2. Adjustment disorder

    American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington, Va: American Psychiatric Publishing. 2013. Powell AD. Grief, bereavement, and adjustment disorders. In: Stern TA, Rosenbaum ...

  3. Evaluation of an adjustable epidemiologic information system.

    Jiunn-Shyan Julian Wu

    Full Text Available BACKGROUND: In order to facilitate public health response and to achieve early control of infectious disease epidemics, an adjustable epidemiologic information system (AEIS was established in the Taiwan public health network in February 2006. METHODOLOGY/PRINCIPAL FINDINGS: The performance of AEIS for the period 2006 through 2008 was evaluated based on a number of response times (RT and the public health impact. After implementation of the system, the apparent overall shortened RT was mainly due to the shortening of personnel response time (PRT and the time needed to draft a new questionnaire that incurred as personnel-system interface (PSI; PRT dropped from a fluctuating range of 9.8 ∼28.8 days in the first four months to <10 days in the following months and remained low till 2008 (0.88±1.52 days. The PSIs for newly emerged infectious diseases were 2.6 and 3.4 person-hours for H5N1 in 2007 and chikungunya in 2008, respectively, a much improvement from 1142.5 person-hours for SARS in 2003. The duration of each rubella epidemic cluster was evaluated as public health impact and showed a shortening trend (p = 0.019 that concurred with the shortening of PRT from 64.8±47.3 to 25.2±38.2 hours per cluster (p<0.0001. CONCLUSIONS/SIGNIFICANCE: The first evaluation of the novel instrument AEIS that had been used to assist Taiwan's multi-level government for infectious diseases control demonstrated that it was well integrated into the existing public health infrastructure. It provided flexible tools and computer algorithms with friendly interface for timely data collection, integration, and analysis; as a result, it shortened RTs, filled in gaps of personnel lacking sufficient experiences, created a more efficient flow of response, and identified asymptomatic/mild cases early to minimize further spreading. With further development, AEIS is anticipated to be useful in the application of other acute public health events needing immediate

  4. The epidemiology of anxiety disorders: a review

    Martin, Patrick

    2003-01-01

    Epidemiological studies show that anxiety disorders are highly prevalent and an important cause of functional impairment; they constitute the most frequent menial disorders in the community. Phobias are the most common with the highest rates for simple phobia and agoraphobia. Panic disorder (PD) and obsessive-compulsive disorder (OCD) are less frequent (2% lifetime prevalence), and there are discordant results for social phobia (SP) (2%-16%) and generalized anxiety disorder (GAD) (3%-30%). Th...

  5. Epidemiology, course, and outcome of eating disorders

    Smink, Frederique R. E.; van Hoeken, Daphne; Hoek, Hans W.

    2013-01-01

    Purpose of reviewTo review the recent literature about the epidemiology, course, and outcome of eating disorders in accordance with the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5).Recent findingsThe residual category eating disorder not otherwise specified' (ED

  6. Epidemiology of psychological disorders in Irish children

    Carr, Alan

    1993-01-01

    Three major epidemiological studies of psychological disorders in Irish children were reviewed. These are the first systematic investigations to be conducted in Ireland and all have been completed within the last 5 years. The studies were conducted in Dublin (N = 2029), Clare (N = 1361) and Cork (N = 733). In all three studies children were screened with the Rutter Teacher Questionnaire. The prevalence rates of children with deviant scores were 17%, 11% and 15% for Dublin, Clare and Cork resp...

  7. Predicting Eating Disorder Continuum Groups: Hardiness and College Adjustment.

    Simon-Boyd, Gail D.; Bieschke, Kathleen J.

    This study examined relationships between hardiness, college adjustment (academic adjustment, social adjustment, personal-emotional adjustment, institutional attachment) and eating disorder (ED) continuum categories in 122 female and 20 male college students. Students who exhibited a higher level of personal-emotional adjustment (PEA) to college…

  8. The Perils of "Adjustment Disorder" as a Diagnostic Category

    Daniels, John

    2009-01-01

    "Adjustment disorder" occupies a peculiar position in the diagnostic system of the Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev.; American Psychiatric Association, 2000) straddling the boundary between normal and abnormal psychology. A more human-centered approach in counseling offers a defense of "normal" adjustment as…

  9. Epidemiology of Eating Disorders: Incidence, Prevalence and Mortality Rates

    Smink, Frédérique R. E.; van Hoeken, Daphne; Hoek, Hans W.

    2012-01-01

    Eating disorders are relatively rare among the general population. This review discusses the literature on the incidence, prevalence and mortality rates of eating disorders. We searched online Medline/Pubmed, Embase and PsycINFO databases for articles published in English using several keyterms relating to eating disorders and epidemiology. Anorexia nervosa is relatively common among young women. While the overall incidence rate remained stable over the past decades, there has been an increas...

  10. Nosology, epidemiology and pathogenesis of bipolar disorder: Recent approaches

    García Blanco, Ana Cristina; Sierra, Pilar; Livianos Aldana, Lorenzo

    2014-01-01

    Bipolar disorder is a highly prevalent, chronic and deteriorating mental illness that requires medical, psychological and social care for life. Realizing that bipolar disorder is more common than initially thought, the associated disability and the heterogeneity in their clinical presentation, has strengthened the research on this topic. Recent advances in the field of nosology, epidemiology and pathogenesis have begun to unravel some of the complexity of this disorder and have had a marked i...

  11. Epidemiology of eating disorders part III: Social epidemiology and case definitions revisited.

    Jan H. Rosenvinge; Pettersen, Gunn

    2015-01-01

    The previous papers in this series outlined a historical panorama and presented updated knowledge about putative risk factors and how eating disorders are distributed in various populations. In this final paper, we discuss in what way comorbidity findings and transdiagnostic issues may change our conceptions about ‘an epidemiological case’ from the current definition of eating disorders based on the recent version of the Diagnostic and Statistical Manual of Mental Disorders (i.e. the DSM-5), ...

  12. Autogenic training as a therapy for adjustment disorder in adolescents

    Jojić Boris R.

    2005-01-01

    Full Text Available INTRODUCTION Autogenic training is a widespread technique used in psychotherapy. The British school of autogenic training cites a large list of diseases, health states, and life changes, in which autogenic training can be of help. We wanted to explore the application of autogenic training as a therapy for adjustment disorder in adolescents. The sample consisted of a homogeneous group of 31 individuals, with an average age of 17.3±0.2 years, who were diagnosed with adjustment disorder, F 43.2, in accordance with ICD 10 search criteria. OBJECTIVE The aim of our work was to figure out the influence of autogenic training on adjustment disorder, through biophysical and biochemical indicators, and to research the efficacy of autogenic training as a therapy for adjustment disorder in adolescents. METHOD We observed adjustment disorder indicators and their changes in three phases, using initial, final, and control values, which we measured immediately before the beginning, immediately after the completion, and six months after the completion, of the practical course in autogenic training. We measured systolic and diastolic arterial blood pressure, brachial pulse rates, cortisol levels in plasma, cholesterol levels in blood, as well as glucose concentrations. During that period, autogenic training was employed as the sole therapy. RESULTS The study confirmed our preliminary assumptions. The measurements we performed showed that arterial blood pressure, pulse rates, cholesterol and cortisol concentrations, after the application of autogenic training among adolescents suffering from adjustment disorder, were lower than the initial values. They remained lower even six months after the completion of the practical course in autogenic training. CONCLUSION We concluded that autogenic training significantly decreases the values of physiological indicators of adjustment disorder, diminishes the effects of stress in an individual, and eases the adaptation of

  13. Classification, Epidemiology and Comorbidity of Addiction Disorders

    Hamid Taherkhani

    2003-08-01

    Full Text Available Revised only twice in the 28 – year period from 1952 to 1980, the American Psychiatric Association`s Diagnostic and Statistical Manual of Mental Disorders (DSM has been amended two more times in half as many years, with the publication of DSM – III – R in 1987 and of DSM – IV in 1994. The DSM counterpart in use outside of North America, the International Classification of Diseases (ICD, also underwent modification during this time period. Requirements for the addictive disorders, or as termed here, psychoactive dependence or abuse disorders, were not immune to change for good reason and to a good end. Unlike other psychiatric disorders, for which ICD and DSM criteria often were the same, a schism existed between the DSM and ICD criteria for addictive disorders.ICD criteria were shaped by an influential article that introduced the construct of a dependence syndrome, but this conceptualization was not operationalized in the DSM system until the publication of DSM – IV. With this latest revision, criteria for substance dependence now closely matches those in the ICD – 10 system, establishing for the first time what may be considered a worldwide classification system for addictive disorders .

  14. The nationwide epidemiological study of mental disorders in korea.

    Lee, C K; Kwak, Y. S.; Rhee, H.; Kim, Y. S.; Han, J. H.; Choi, J. O.; Lee, Y H

    1987-01-01

    The lifetime prevalences of DSM-III mental disorders using Korean version of DIS-III are presented. They were studied in 5,100 adults (aged 18 to 65) in household selected by two stage cluster sampling. Comparisons were made between regions, sex and age groups. International comparison with Epidemiologic Catchment Area program was also made.

  15. Classification, Epidemiology and Comorbidity of Addiction Disorders

    Hamid Taherkhani

    2003-01-01

    Revised only twice in the 28 – year period from 1952 to 1980, the American Psychiatric Association`s Diagnostic and Statistical Manual of Mental Disorders (DSM) has been amended two more times in half as many years, with the publication of DSM – III – R in 1987 and of DSM – IV in 1994. The DSM counterpart in use outside of North America, the International Classification of Diseases (ICD), also underwent modification during this time period. Requirements for the addictive disorders, or as term...

  16. An Epidemiological Study of Psychiatric Disorders in Hamadan Province , 2001

    M.R. Mohammadi

    2004-10-01

    Full Text Available The burden of psychiatric disorders in the developed countries has been identified by the screening questionnaires and standard clinical interviews at a high level, but the epidemiological studies of psychiatric disorders in our country are brief and their numbers are few. Planning for providing essential mental health services to the people requires us to be knowledgeable about the present status of psychiatric disorders in the society. The objective of this research was to carry out the epidemiological study of the psychiatric disorders in the individuals 18 years and above in urban and rural areas of Hamadan province. 664 individuals selected through randomized clustered and systematic sampling methods among the existing families of Hamadan province and the Schedule for Affective Disorders and Schizophrenia (SADS questionnaires completed by the clinical psychologist. The diagnosis of the disorders was based on DSM-IV classification criteria.The results of the study showed that the overall prevalence of psychiatric disorders in the province was 11.28% (17.2% in women , 5.8% in men. The anxiety and mood disorders with 5.87 and 2.71% respectively had the highest prevalence in the province. The prevalence of psychotic disorders in this study was 0.60% , neuro- cognitive disorders 1.35% and dissociative disorders 0.75%. In the group of mood disorders, major depression with 2.56% and in the group of anxiety disorders, phobia with 2.56% had the higher prevalence. This study showed that 8.13% of studied individuals suffered from at least one of the psychiatric disorders. The prevalence of psychiatric disorders in the province among the individuals in the age group of 66 years and above was 13.33%, individuals whose spouses had passed away 18.75%, urban residents of province 9.81%, illiterate individuals 12.80% and housewife individuals 12.31% was more than other individuals in the sample. Being aware of this matter reveals the responsibility of the

  17. EPIDEMIOLOGICAL FINDINGS ON PREVALENCE OF MENTAL DISORDERS IN INDIA

    Ganguli, H.C.

    2000-01-01

    Fifteen epidemiological studies on psychiatric morbidity in India have been analysed. National all-India prevalence rates for ‘all mental disorders’ and five specific disorders have been worked out The national prevalence rates for ‘all mental disorders’ arrived at are 70.5 (rural), 73 (urban) and 73 (rural + urban) per 1000 population. Prevalence of schizophrenia is 2.5/1000 and this seems to be the only disorder whose prevalence is consistent across cultures and over time. Rates for depress...

  18. Autism spectrum disordersepidemiology, symptoms, comorbidity and diagnosis

    Filip Rybakowski,

    2014-08-01

    Full Text Available In the new classification of American Psychiatric Association – DSM-5 – a category of autistic spectrum disorders (ASD was introduced, which replaced autistic disorder, Asperger syndrome, childhood disintegrative disorder and pervasive developmental disorder not otherwise specified. ASD are defined by two basic psychopathological dimensions: communication disturbances and stereotyped behaviors, and the diagnosis is complemented with the assessment of language development and intellectual level. In successive epidemiological studies conducted in 21 century the prevalence of ASD has been rising, and currently is estimated at 1% in general population. The lifetime psychiatric comorbidity is observed in majority of patients. The most common coexisting diagnoses comprise disorders of anxiety-affective spectrum, and in about 1/3 of patients attention deficit/ hyperactivity disorders could be diagnosed. Prodromal symptoms of ASD may emerge before 12 months of life, however reliability of diagnosis at such an early age is poor. Several screening instruments, based on the parental and/or healthcare professional assessments may be helpful in ASD detection. However, structured interviews and observation schedules remain the gold standard of diagnosis.

  19. An epidemiological study of mental disorders at Pune, Maharashtra

    Balbir S Deswal

    2012-01-01

    Full Text Available Background: The WHO Global Burden of Disease study estimates that mental and addictive disorders are among the most burdensome in the world, and their burden will increase over the next decades. The mental and behavioral disorders account for about 12% of the global burden of disease. However, these estimates and projections are based largely on literature review rather than cross-national epidemiological surveys. In India, little is known about the extent, severity and unmet need of treatment mental disorders. Thus, there was a need to carry out rigorously implemented general population surveys that estimate the prevalence of mental disorders among urban population at Pune, Maharashtra. The study attempted to address unmet need and to form a basis for formulating the mental health need of the community. Objective: The study was undertaken to estimate the lifetime prevalence and 12 month prevalence of specific mental disorders in urban population, socio-demographic correlates of mental disorders and to assess the service utilization in individuals with mental disorders. Materials and Methods: The study was undertaken among adults aged 18 years and above living in house hold and in geographical area of Pune , Maharashtra. A minimum sample of 3000 completed interviews was planned using representative probabilities to population size (PPS sampling method which ensured equal probability for every eligible member. Data listing was obtained from Census Office from recent census of 2001 data. The face to face interviews were undertaken in homes using fully structured interview schedule of World Mental Health Survey Initiative duly revised Version of WHO- Composite International Diagnostic Interview (CIDI 3.0 by trained investigators. Clinical reappraisal was carried out using Schedules for Clinical Assessment in Neuropsychiatry (SCAN among ten percent of diagnosed cases selected randomly. Data were entered into DDE (Blaize Software and analyzed using

  20. Epidemiology of eating disorders, eating disordered behaviour, and body image disturbance in males: a narrative review.

    Mitchison, Deborah; Mond, Jonathan

    2015-01-01

    Challenges to epidemiological studies of eating and related body image disturbance disorders in males include, in addition to low base rates and the predominance of residual diagnostic categories, the female-centric nature of current classification schemes and the consequent lack of appropriate assessment instruments. In this narrative review, we summarise epidemiological data regarding the prevalence and correlates of eating disorders, related body image disturbance disorders, and eating disorder features in males. Attention is focused on disorders most likely to be observed among males, such as muscle dysmorphia and muscularity-oriented excessive exercise. It is argued that, given the multiple challenges involved in research of this kind, a focus on features is more likely to advance the field than a focus on diagnoses. In terms of correlates, we focus on impairment and help-seeking, since these issues are most relevant in informing public health burden, service provision, and related issues. We end with some thoughts about current gaps in the knowledge base and directions for future research that we consider to be most promising. PMID:27408719

  1. Epidemiologia do transtorno bipolar Epidemiology of bipolar disorders

    Maurício Silva de Lima

    2005-01-01

    Full Text Available A formulação de políticas em saúde mental depende essencialmente de informações a respeito da freqüência e distribuição dos transtornos mentais. Nas últimas duas décadas, pesquisas de base populacional em epidemiologia psiquiátrica têm sido conduzidas, gerando informações detalhadas sobre freqüência, fatores de risco, incapacidade social e utilização de serviços de saúde. Neste artigo, dados sobre a epidemiologia do transtorno bipolar (TB são discutidos, a partir de resultados de recentes pesquisas populacionais: o estudo da Área de Captação Epidemiológica do Instituto Nacional de Saúde Mental dos Estados Unidos (ECA-NIMH, a Pesquisa Nacional de Comorbidade (NCS, a Pesquisa de Morbidade Psiquiátrica na Grã-Bretanha (OPCS, o Estudo Brasileiro Multicêntrico de Morbidade Psiquiátrica e os estudos longitudinais conduzidos por Angst, em Zurique. As estimativas de prevalências de transtorno bipolar são relativamente baixas, independentemente do lugar onde a pesquisa foi conduzida, do tipo de instrumento diagnóstico usado e dos períodos de tempo para os quais a prevalência se aplica. A partir da introdução do conceito de espectro bipolar, ampliando as fronteiras diagnósticas do TB, as estimativas de prevalências encontradas são substancialmente mais altas. Tais estimativas, entretanto, ainda carecem de validação em estudos populacionais. O transtorno afetivo bipolar é igualmente prevalente entre homens e mulheres, sendo mais freqüente entre solteiros ou separados. Indivíduos acometidos têm maiores taxas de desemprego e estão mais sujeitos a utilizarem serviços médicos e serem hospitalizados. O custo e a eficácia dos tratamentos do TB devem ser balanceados com o alto custo individual e social associados à enfermidade.Information about the epidemiology of bipolar disorders is essential for providing a framework for the formulation of effective mental health policy. In the last two decades, population

  2. Social anxiety disorder: recent findings in the areas of epidemiology, etiology, and treatment.

    Blanco, C; Nissenson, K; Liebowitz, M R

    2001-08-01

    Social anxiety disorder is a common and chronic disorder that leads to substantial psychosocial impairment. The disorder occurs early in childhood, and is frequently comorbid with a variety of other psychiatric diagnoses like depression, other anxiety disorders, substance abuse, and eating disorders. Given these serious implications of social anxiety disorder, early effective treatment is extremely important. Pharmacotherapy, with a selective serotonin reuptake inhibitor, and cognitive behavioral therapy are the first choice of treatments for social anxiety disorder. This paper reviews recent findings on the epidemiology, etiology, and treatment for social anxiety disorder, and highlights areas where future research should be directed. PMID:11470033

  3. The epidemiology of eating disorders: genetic, environmental, and societal factors

    Mitchison D

    2014-02-01

    Full Text Available Deborah Mitchison,1 Phillipa J Hay2,3 1School of Medicine, University of Western Sydney, Sydney, NSW, Australia; 2Centre for Health Research, School of Medicine, University of Western Sydney, Sydney, NSW, Australia; 3School of Medicine, James Cook University, Townsville City, QLD, Australia Background: The aim of this review was to summarize the literature to date regarding the sociodemographic, environmental, and genetic correlates of eating disorders (EDs in adults. Method: A keyword search was entered into Scopus (SciVerse, Elsevier to identify relevant articles published in English up until June 2013. Articles were assessed against a range of a priori inclusion and exclusion criteria. Results: A total of 149 full-text articles were found to be eligible for the review and included 86 articles with data on sociodemographic correlates, 57 on environmental correlates, and 13 on genetic correlates. Female sex, younger age, sexual and physical abuse, participation in esthetic or weight-oriented sports, and heritability were found to be most consistently associated with higher ED prevalence and incidence. Conversely, ethnicity, socioeconomic status, education, and urbanicity did not appear to have strong associations with ED epidemiology. Conclusion: More community-based research, with an equal representation of males, needs to be conducted to confirm the current findings and provide evidence for emerging factors that may be related to EDs. Keywords: demographic, environment, abuse, prevalence, socioeconomic status, heritability

  4. Interventions to facilitate return to work in adults with adjustment disorders

    Arends, Iris; Bruinvels, David J.; Rebergen, David S.; Nieuwenhuijsen, Karen; Madan, Ira; Neumeyer-Gromen, Angela; Bultmann, Ute; Verbeek, Jos H.

    2012-01-01

    Background Adjustment disorders are a frequent cause of sick leave and various interventions have been developed to expedite the return to work (RTW) of individuals on sick leave due to adjustment disorders. Objectives To assess the effects of interventions facilitating RTW for workers with acute or

  5. Epidemiology of anxiety disorders in the 21st century

    Bandelow, Borwin; Michaelis, Sophie

    2015-01-01

    Anxiety disorders, including panic disorder with or without agoraphobia, generalized anxiety disorder, social anxiety disorder, specific phobias, and separation anxiety disorder, are the most prevalent mental disorders and are associated with immense health care costs and a high burden of disease. According to large population-based surveys, up to 33.7% of the population are affected by an anxiety disorder during their lifetime. Substantial underrecognition and undertreatment of these disorde...

  6. Epidemiology in a changing world: implications for population-based research on mental disorders.

    Cooper, B

    2014-06-01

    Introduction and objectives. Population-based research on mental disorders needs to keep pace with trends in general epidemiology. At present, this requirement is complicated by uncertainty within the parent discipline about its future development. The present study examines proposals for new directions in strategy and methods and considers their significance for psychiatric epidemiology. Method. Narrative review, cross-checked by search of English-language journals of epidemiology for new trends and developments reported in the years from 2000 onwards. Results. The proposals reviewed here are divided into three groups: 1. A new research paradigm of 'eco-epidemiology', which includes both individual risk factors and macro-environmental systems that mediate population levels of health and sickness. 2. Improved 'translation' of research findings - i.e. more rapid and effective implementation of epidemiological evidence into health policy and practice. 3. Adaptation of epidemiology to a globalised economy, with firmer regulation of funding and resources. Conclusions. Each of these proposals has implications for psychiatric epidemiology. Workers in this field, however, are still preoccupied by relatively specific problems of definition, measurement and classification, and so far the current debates in general epidemiology are scarcely reflected. The proposals outlined above call for: • a working model of eco-epidemiology as it relates to psychiatric disorders; • implementation strategies to encourage more active participation in epidemiological research by community health services and caregiver organisations; • international collaborative projects that offer practical benefits in training and service facilities for the countries taking part. PMID:24345606

  7. Epidemiology of anxiety disorders in the 21st century.

    Bandelow, Borwin; Michaelis, Sophie

    2015-09-01

    Anxiety disorders, including panic disorder with or without agoraphobia, generalized anxiety disorder, social anxiety disorder, specific phobias, and separation anxiety disorder, are the most prevalent mental disorders and are associated with immense health care costs and a high burden of disease. According to large population-based surveys, up to 33.7% of the population are affected by an anxiety disorder during their lifetime. Substantial underrecognition and undertreatment of these disorders have been demonstrated. There is no evidence that the prevalence rates of anxiety disorders have changed in the past years. In cross-cultural comparisons, prevalence rates are highly variable. It is more likely that this heterogeneity is due to differences in methodology than to cultural influences. Anxiety disorders follow a chronic course; however, there is a natural decrease in prevalence rates with older age. Anxiety disorders are highly comorbid with other anxiety disorders and other mental disorders. PMID:26487813

  8. The Co-Occurrence of Reading Disorder and ADHD: Epidemiology, Treatment, Psychosocial Impact, and Economic Burden

    Sexton, Chris C.; Gelhorn, Heather L.; Bell, Jill A.; Classi, Peter M.

    2012-01-01

    The co-occurrence of reading disorder (RD) and attention-deficit/hyperactivity disorder (ADHD) has received increasing attention. This review summarizes the epidemiology, treatment strategies, psychosocial impact, and economic burden associated with the co-occurrence of these conditions. Common genetic and neuropsychological deficits may partially…

  9. The association between adjustment disorder diagnosed at psychiatric treatment facilities and completed suicide

    Gradus, Jaimie L; Qin, Ping; Lincoln, Alisa K; Miller, Matthew; Lawler, Elizabeth; Lash, Timothy L

    2010-01-01

    associated with suicidal ideation and suicide attempt. However the association between adjustment disorder and completed suicide has yet to be examined. The current study is a population-based case control study examining this association in the population of Denmark aged 15 to 90 years. All suicides in...... Denmark from 1994 to 2006 were included, resulting in 9,612 cases. For each case, up to 30 controls were matched on gender, exact date of birth, and calendar time, yielding 199,306 controls. Adjustment disorder diagnosis was found in 7.6% of suicide cases and 0.52% of controls. Conditional logistic...... regression analyses revealed that those diagnosed with adjustment disorder had 12 times the rate of suicide as those without an adjustment disorder diagnosis, after controlling for history of depression diagnosis, marital status, income, and the matched factors....

  10. Youths with ADHD with and without Tic Disorders: Comorbid Psychopathology, Executive Function and Social Adjustment

    Lin, Yu-Ju; Lai, Meng-Chuan; Gau, Susan Shur-Fen

    2012-01-01

    Attention deficit/hyperactivity disorder (ADHD) and tic disorders (TD) commonly co-occur. Clarifying the psychiatric comorbidities, executive functions and social adjustment difficulties in children and adolescents of ADHD with and without TD is informative to understand the developmental psychopathology and to identify their specific clinical…

  11. Comorbidity of Social Anxiety Disorder and Antisocial Personality Disorder in the National Epidemiological Survey on Alcohol and Related Conditions (NESARC)

    Galbraith, Todd; Heimberg, Richard G.; Wang, Shuai; Schneier, Franklin R.; Blanco, Carlos

    2013-01-01

    Social anxiety disorder (SAD) and antisocial personality disorder (ASPD) are not often thought of as being comorbid. However, recent research suggests the existence of a SAD subtype with characteristics atypical of SAD but common to ASPD. Thus, we explored two competing hypotheses: 1) SAD and ASPD represent opposite ends of a single dimension, or 2) SAD and ASPD exist on two separate dimensions that may be positively correlated. Data were obtained from the National Epidemiological Survey on A...

  12. Challenges for environmental epidemiology research: are biomarker concentrations altered by kidney function or urine concentration adjustment?

    Biological monitoring has become a standard approach to exposure assessment in occupational and environmental epidemiology. The use of biological effect markers to identify early adverse changes in target organs has also become widely adopted. Recently, nephrotoxicant research us...

  13. Skin disorders in diabetes mellitus: an epidemiology and physiopathology review.

    de Macedo, Geisa Maria Campos; Nunes, Samanta; Barreto, Tania

    2016-01-01

    Skin disorders, usually neglected and frequently underdiagnosed among diabetic patients, are common complications and encounter a broad spectrum of disorders in both type 1 and type 2 diabetes mellitus (DM)-e.g. cutaneous infection, dry skin, pruritus. Skin disorders are highly associated with increased risk of important outcomes, such as skin lesions, ulcerations and diabetic foot, which can lead to major complications and revolve around multifactorial factors besides hyperglycemia and advanced glycation end products. Although diabetic's skin disorders are consistent in the literature, there is limited data regarding early-stage skin disorders in DM patients. Disease control, early-stage treatment (e.g. skin hydration, orthotic devices) and awareness can reduce morbidity of DM patients. Thus, better understanding of the burden of skin disorders in DM patients may raise awareness on prevention and management. Therefore, the aim of this study is to perform a literature review to evaluate the main clinical characteristics and complications of skin disorders in diabetic's patients. Additionally, physiopathology early-stage skin disorders and dermocosmetic management were also reviewed. PMID:27583022

  14. Epidemiology of Eating Disorders : Incidence, Prevalence and Mortality Rates

    Smink, Frederique R. E.; van Hoeken, Daphne; Hoek, Hans W.

    2012-01-01

    Eating disorders are relatively rare among the general population. This review discusses the literature on the incidence, prevalence and mortality rates of eating disorders. We searched online Medline/Pubmed, Embase and PsycINFO databases for articles published in English using several keyterms rela

  15. Childhood Mental Disorders in Great Britain: An Epidemiological Perspective

    Meltzer, Howard

    2007-01-01

    The objective of this article is to describe the prevalence of childhood disorders and examine the factors associated with higher rates of disorder by combining the data from two large population-based samples of British children and young people aged 5-15. Just over 18,000 children were assessed in 1999 and 2004 using the Development and…

  16. Methods for evaluating work-related musculoskeletal neck and upper-extremity disorders in epidemiological studies

    Toomingas, Allan

    1998-01-01

    The aim of this thesis was to develop, evaluate and characterise assessment methods used within epidemiological studies of work-related musculoskeletal disorders in the neck and upper extremities. Special attention was paid to self-administered methods, relations to psychosocial risk factors and signs of nerve compression. Work-related musculoskeletal disorders in the neck and upper extremities are common and costly in many respects. Knowledge about the progression of th...

  17. Epidemiology of communication disorders in childhood phoniatric clinical practice

    Marta Gonçalves Gimenez Baptista

    2015-08-01

    Full Text Available INTRODUCTION: Language acquisition and development require an understanding of physical and psychosocial aspects during diagnosis and treatment. At this point, a partnership between phoniatric physicians and other health professionals is often a determinant for favorable prognosis.OBJECTIVE: To identify the clinical and epidemiological characteristics of a pediatric population attending a phoniatric clinical practice.METHODS: Study design: Cross-sectional cohort. Retrospective, epidemiological study of 297 children, seen in phoniatric appointments between 1976 and 2005. Outcome variables were referral origin, gender, age, mean age, diagnosis, and treatment approach.RESULTS: 66% were male and 34% were female, with a mean age of 6.4 years. The largest number of referrals for phoniatric treatments came from speech therapists (38%. The predominant complaint was alteration in speech (35%; the diagnostics in speech, language, and fluency (49.5% are noteworthy. Considering the total of the patients analyzed, 28.2% were referred for speech therapy and 11.8% for psychotherapy.CONCLUSION: The studied population is predominantly male, the diagnosis points to a higher incidence in cases of impairment in speech, language, and fluency; the most common treatment was speech therapy.

  18. The epidemiology of attention-deficit/hyperactivity disorder (ADHD): a public health view.

    Rowland, Andrew S; Lesesne, Catherine A; Abramowitz, Ann J

    2002-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood. However, basic information about how the prevalence of ADHD varies by race/ethnicity, sex, age, and socio-economic status remains poorly described. One reason is that difficulties in the diagnosis of ADHD have translated into difficulties developing an adequate case definition for epidemiologic studies. Diagnosis depends heavily on parent and teacher reports; no laboratory tests reliably predict ADHD. Prevalence estimates of ADHD are sensitive to who is asked what, and how information is combined. Consequently, recent systematic reviews report ADHD prevalence estimates as wide as 2%-18%. The diagnosis of ADHD is complicated by the frequent occurrence of comorbid conditions such as learning disability, conduct disorder, and anxiety disorder. Symptoms of these conditions may also mimic ADHD. Nevertheless, we suggest that developing an adequate epidemiologic case definition based on current diagnostic criteria is possible and is a prerequisite for further developing the epidemiology of ADHD. The etiology of ADHD is not known but recent studies suggest both a strong genetic link as well as environmental factors such as history of preterm delivery and perhaps, maternal smoking during pregnancy. Children and teenagers with ADHD use health and mental health services more often than their peers and engage in more health threatening behaviors such as smoking, and alcohol and substance abuse. Better methods are needed for monitoring the prevalence and understanding the public health implications of ADHD. Stimulant medication is the treatment of choice for treating ADHD but psychosocial interventions may also be warranted if comordid disorders are present. The treatment of ADHD is controversial because of the high prevalence of medication treatment. Epidemiologic studies could clarify whether the patterns of ADHD diagnosis and treatment in community settings is

  19. Disorders of identity and sexual behavior: an epidemiological approach

    Ieda Aparecida Diniz

    2013-05-01

    Full Text Available The research aimed to characterize patients affected by Identity Disorders and Sexual Behavior and identify their occurrence by sex, as well as the patient's origin, diagnosis and length of stay, type of admission and discharge and funding source for services rendered. This is a retrospective study conducted in a psychiatric clinic in the Midwest Miner. The sample consisted of 2715 patients, predominantly male (1518- 55.9%, age range 21-30 years (917- 33.7%, the origin of hospitalization for Psychosocial Care Centers (1123 - 41.3%, the diagnosis of "Other Disorders of sexual preference" (2567- 94.5%, the residence time of 1 to 30 days (1770-65.2%, the high medical (1818-66,9%, the first admissions (1775-65.3% and Health System as the main funder (2004 to 73.1%. It was evident that the disorders are more common in young men and it was realized how little knowledge of health professionals about these disorders.

  20. [Epidemiology of schizophrenic disorders, genetic and environmental risk factors].

    Szoke, Andrei

    2013-03-01

    Schizophrenia is a relatively common pathology with onset at adolescence or early adulthood, more frequent in men than women. By describing distribution of cases in different populations and the factors that influence this distribution, epidemiology contributes to our understanding of the disease. Several risk factors for schizophrenia have been uncovered both genetic and environmental. The environmental factors can act at individual level (obstetric complications, season of birth, urbanicity, childhood trauma, cannabis, migration) or at population/area levels (socio-economic level, social fragmentation and social capital, ethnic density, etc.). An integrative and dynamic model based on the "vulnerability-persistence-impairment" paradigm is useful in integrating the findings about the risk factors and their complex relationships. PMID:23687754

  1. The epidemiology of eating disorders: genetic, environmental, and societal factors

    Mitchison D; Hay PJ

    2014-01-01

    Deborah Mitchison,1 Phillipa J Hay2,3 1School of Medicine, University of Western Sydney, Sydney, NSW, Australia; 2Centre for Health Research, School of Medicine, University of Western Sydney, Sydney, NSW, Australia; 3School of Medicine, James Cook University, Townsville City, QLD, Australia Background: The aim of this review was to summarize the literature to date regarding the sociodemographic, environmental, and genetic correlates of eating disorders (EDs) in adults. Method: A keyword sear...

  2. Male eating disorders and related traits : Genetic epidemiological study in Finnish twins

    Raevuori, Anu

    2009-01-01

    The aim of this study was to deepen the understanding of eating disorders, body image dissatisfaction and related traits in males by examining the epidemiology and genetic epidemiology of these conditions in representative population-based twin samples. The sample of Study I included adolescent twins from FinnTwin12 cohorts born 1983 87 and assessed by a questionnaire at ages 14 y (N=2070 boys, N=2062 girls) and 17 y (N=1857 boys, N=1984 girls). Samples of Studies II-V consisted of young...

  3. Siblings of Youth with Autism Spectrum Disorders: Theoretical Perspectives on Sibling Relationships and Individual Adjustment

    McHale, Susan M.; Updegraff, Kimberly A.; Feinberg, Mark E.

    2016-01-01

    A burgeoning research literature investigates the sibling relationships of youth with autism spectrum disorder (ASD) and their implications for individual adjustment. Focusing on four relationship domains--behaviors, emotions, cognitions and involvement--and toward advancing this generally atheoretical literature, we review and apply tenets from a…

  4. Epidemiological and clinical characterization following a first psychotic episode in major depressive disorder: Comparisons with Schizophrenia and Bipolar I Disorder in the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS).

    Owoeye, Olabisi

    2013-05-28

    While recent research on psychotic illness has focussed on the nosological, clinical, and biological relationships between schizophrenia and bipolar disorder, little attention has been directed to the most common other psychotic diagnosis, major depressive disorder with psychotic features (MDDP). As this diagnostic category captures the confluence between dimensions of psychotic and affective psychopathology, it is of unappreciated heuristic potential to inform on the nature of psychotic illness. Therefore, the epidemiology and clinical characteristics of MDDP were compared with those of schizophrenia and bipolar disorder within the Cavan-Monaghan First Episode Psychosis Study (n = 370). Epidemiologically, the first psychotic episode of MDDP (n = 77) was uniformly distributed across the adult life span, while schizophrenia (n = 73) and bipolar disorder (n = 73) were primarily disorders of young adulthood; the incidence of MDDP, like bipolar disorder, did not differ between the sexes, while the incidence of schizophrenia was more common in males than in females. Clinically, MDDP was characterized by negative symptoms, executive dysfunction, neurological soft signs (NSS), premorbid intellectual function, premorbid adjustment, and quality of life similar to those for schizophrenia, while bipolar disorder was characterized by less prominent negative symptoms, executive dysfunction and NSS, and better quality of life. These findings suggest that what we currently categorize as MDDP may be more closely aligned with other psychotic diagnoses than has been considered previously. They indicate that differences in how psychosis is manifested vis-à-vis depression and mania may be quantitative rather than qualitative and occur within a dimensional space, rather than validating categorical distinctions.

  5. [Paraphilia, sexual preference disorders. Diagnosis, etiology, epidemiology, treatment and prevention].

    Berner, Wolfgang; Briken, P

    2007-01-01

    Hostility towards relationships is one prominent characteristic symptom for disorders of sexual preference (ICD-10) and paraphilias (DSM-IV). Paraphilic symptoms sometimes progress to obsessive or addictive- like forms leading to a loss of self-control but can occur also as single incidents or as episodic events. Besides constitutional aspects, problems in the development of close relationships to primary caregivers (attachment) play an important role in the development of these disorders. Actual relationship- and self-confidence problems often trigger the severity of disturbance, especially in the episodic forms of paraphilia. For patients who are in conflict with the law, cognitive-behavioral therapeutic approaches with the aim to minimize self-deception regarding the effects of the paraphilic behavior have become more and more relevant. Regarding the medical treatment, anti-hormonal therapy plays an important role, but also treatment with serotonergic agents and naltrexone are used. Only little can be advised in terms of prevention; general psycho-hygiene (regarding the parent-child relationship) is recommended. Beside these general measures, institutions which offer special treatment for people in danger to become delinquents may be able to prevent serious harm for possible victims of abuse. PMID:17177100

  6. Trauma, comorbidity, and mortality following diagnoses of severe stress and adjustment disorders: a nationwide cohort study.

    Gradus, Jaimie L; Antonsen, Sussie; Svensson, Elisabeth; Lash, Timothy L; Resick, Patricia A; Hansen, Jens Georg

    2015-09-01

    Longitudinal outcomes following stress or trauma diagnoses are receiving attention, yet population-based studies are few. The aims of the present cohort study were to examine the cumulative incidence of traumatic events and psychiatric diagnoses following diagnoses of severe stress and adjustment disorders categorized using International Classification of Diseases, Tenth Revision, codes and to examine associations of these diagnoses with all-cause mortality and suicide. Data came from a longitudinal cohort of all Danes who received a diagnosis of reaction to severe stress or adjustment disorders (International Classification of Diseases, Tenth Revision, code F43.x) between 1995 and 2011, and they were compared with data from a general-population cohort. Cumulative incidence curves were plotted to examine traumatic experiences and psychiatric diagnoses during the study period. A Cox proportional hazards regression model was used to examine the associations of the disorders with mortality and suicide. Participants with stress diagnoses had a higher incidence of traumatic events and psychiatric diagnoses than did the comparison group. Each disorder was associated with a higher rate of all-cause mortality than that seen in the comparison cohort, and strong associations with suicide were found after adjustment. This study provides a comprehensive assessment of the associations of stress disorders with a variety of outcomes, and we found that stress diagnoses may have long-lasting and potentially severe consequences. PMID:26243737

  7. Cigarette smoking, nicotine dependence and anxiety disorders: a systematic review of population-based, epidemiological studies

    Moylan Steven

    2012-10-01

    Full Text Available Abstract Background Multiple studies have demonstrated that rates of smoking and nicotine dependence are increased in individuals with anxiety disorders. However, significant variability exists in the epidemiological literature exploring this relationship, including study design (cross-sectional versus prospective, the population assessed (random sample versus clinical population and diagnostic instrument utilized. Methods We undertook a systematic review of population-based observational studies that utilized recognized structured clinical diagnostic criteria (Diagnostic and Statistical Manual of Mental Disorders (DSM or International Classification of Diseases (ICD for anxiety disorder diagnosis to investigate the relationship between cigarette smoking, nicotine dependence and anxiety disorders. Results In total, 47 studies met the predefined inclusion criteria, with 12 studies providing prospective information and 5 studies providing quasiprospective information. The available evidence suggests that some baseline anxiety disorders are a risk factor for initiation of smoking and nicotine dependence, although the evidence is heterogeneous and many studies did not control for the effect of comorbid substance use disorders. The identified evidence however appeared to more consistently support cigarette smoking and nicotine dependence as being a risk factor for development of some anxiety disorders (for example, panic disorder, generalized anxiety disorder, although these findings were not replicated in all studies. A number of inconsistencies in the literature were identified. Conclusions Although many studies have demonstrated increased rates of smoking and nicotine dependence in individuals with anxiety disorders, there is a limited and heterogeneous literature that has prospectively examined this relationship in population studies using validated diagnostic criteria. The most consistent evidence supports smoking and nicotine dependence as

  8. Advances in epidemiological study of post-traumatic stress disorders in postwar civilian survivors

    Kong, Xiang-Yu; Li-ning XIAO; Huang, Wen; Li, Zhao-Shen

    2012-01-01

    Post-traumatic stress disorder (PTSD) is a feeling of persecution arising from the exposure to a life-threatening event. PTSD shows three kinds of characteristic symptoms including intrusive, avoidance, and arousal syndromes. Numerous literatures had been published on the study of the PTSD epidemiology. However, research results varied due to different research subjects and evaluation methods used. A big difference exists between the studies on refugees, migrating population, and community po...

  9. Epidemiology and clinical features of obsessive-compulsive disorder during pregnancy and postpartum period: a review

    Uguz, Faruk; Ayhan, Medine Gıynas

    2011-01-01

    In this study we reviewed the current literature on the epidemiology and clinical features of obsessive-compulsive disorder (OCD) during pregnancy and postpartum period. The available reports on this topic have significant limitations and heterogenous methods. However, the prevalence and incidence rates of OCD reported during these two reproductive periods are higher than the rates estimated in the general population. The most common obsessions in pregnancy and puerperium were contamination a...

  10. Epidemiology and health service resource allocation policy for alcohol, drug abuse, and mental disorders.

    Regier, D A; S. Shapiro; Kessler, L G; Taube, C A

    1984-01-01

    Data from the NIMH Epidemiologic Catchment Area (ECA) Study in Baltimore, Md., are used to illustrate the association between alcohol, drug abuse, and mental disorder diagnoses with health service use. A probability sample of 3,481 adult (age 18 and over) residents of a geographically defined Baltimore City population of 175,000 was found to have a 23.4 per 100 population, 6-month prevalence of 13 specific alcohol, drug, and mental disorders. Of this population, 7.1 percent sought outpatient ...

  11. Associations among trauma, posttraumatic stress disorder, cannabis use, and cannabis use disorder in a nationally representative epidemiologic sample.

    Kevorkian, Salpi; Bonn-Miller, Marcel O; Belendiuk, Katherine; Carney, Dever M; Roberson-Nay, Roxann; Berenz, Erin C

    2015-09-01

    Research in community and clinical samples has documented elevated rates of cannabis use and cannabis use disorders (CUDs) among individuals with trauma exposure and posttraumatic stress disorder (PTSD). However, there is a lack of research investigating relations between, and correlates of, trauma and cannabis phenotypes in epidemiologic samples. The current study examined associations between trauma (i.e., lifetime trauma exposure and PTSD) and cannabis phenotypes (i.e., lifetime cannabis use and CUD) in a nationally representative sample. Participants were individuals who participated in Waves 1 and 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (n = 34,396; 52.4% women; age, M = 48.0 years, SD = 16.9). Lifetime DSM-IV Criterion A trauma exposure was significantly associated with lifetime cannabis use (OR = 1.215) but was only marginally associated with CUD (OR = 0.997). Within the trauma-exposed sample, lifetime PTSD showed a significant association with CUD (OR = 1.217) but was only marginally associated with lifetime cannabis use (OR = 0.992). Partially consistent with hypotheses, lifetime trauma was associated with greater odds of lifetime cannabis use, whereas PTSD was associated with greater odds of CUD. Longitudinal research investigating patterns of onset of these events/disorders is needed. PMID:26415060

  12. TEO: an online emotional therapy system to apply homework assignments in the Treatment of adjustment disorders

    Quero Castellano, Soledad; Botella Arbona, Cristina; Pérez Ara, María Ángeles; Andreu Mateu, Maria Sabrina; Baños Rivera, Rosa María; Castilla López, Diana Virginia

    2011-01-01

    Adjustment Disorders (AD) are a very important public health problem. Regarding its treatment, only a series of general guidelines are available. Our research team has developed a cognitive-behavioral treatment (CBT) supported by Virtual Reality (VR) that has shown its utility in the treatment of AD. A CBT approach gives a crucial role to homework assignments. So far, studies that use Information and Communication Technologies (ICT) for psychological treatments have been ...

  13. Siblings of Youth with Autism Spectrum Disorders: Theoretical Perspectives on Sibling Relationships and Individual Adjustment.

    McHale, Susan M; Updegraff, Kimberly A; Feinberg, Mark E

    2016-02-01

    A burgeoning research literature investigates the sibling relationships of youth with autism spectrum disorder (ASD) and their implications for individual adjustment. Focusing on four relationship domains—behaviors,emotions, cognitions and involvement—and toward advancing this generally a theoretical literature, were view and apply tenets from a range of theoretical perspectives in an effort to illuminate the mechanisms underlying sibling relationship experiences and their adjustment implications. Our review suggests new directions for research to test theoretically-grounded hypotheses about how sibling relationships develop and are linked to individual adjustment. In addition, we consider how identifying underlying bio-psycho-social processes can aid in the development of interventions to promote warm and involved sibling relationships and positive youth development. PMID:26476737

  14. Epidemiology of sleep apnoea/hypopnoea syndrome and sleep-disordered breathing

    Jennum, P; Riha, R L

    2009-01-01

    Epidemiological studies have revealed a high prevalence of sleep-disordered breathing in the community (up to 20%). A subset of these patients has concurrent symptoms of excessive daytime sleepiness attributable to their nocturnal breathing disorder and is classified as having obstructive sleep...... apnoea/hypopnoea syndrome (4-5% of the middle-aged population). There is strong evidence for an association of sleep apnoea with cardiovascular and cerebrovascular morbidity, as well as adverse public health consequences. Treatment and diagnosis have remained largely unchanged over the past 25 yrs. In...... moderate-to-severe obstructive sleep apnoea/hypopnoea syndrome, treatment with continuous positive airway pressure has been shown to be effective. Questions remain as to how to screen patients with sleep-disordered breathing. Should time-consuming diagnostic procedures with high sensitivity and specificity...

  15. [The epidemiology of eating disorders and the influence of mass media: a literature review].

    Guerro-Prado, D; Barjau Romero, J M; Chinchilla Moreno, A

    2001-01-01

    The aim of this study was to provide an update of the epidemiology of eating disorders (anorexia nervosa and bulimia nervosa), focusing on incidence and prevalence as well as other factors as age and sex. We made a review of the existing literature in the matter in the last decades. Likewise, we made an extent evaluation of the hypothetical pathogenic impact that exerts mass media (television and printed mass media) in these pathologies. We found an evident increase in incidence as well as prevalence of these disorders though it's far from being considered epidemic. We also found an undeniable influence of mass media in the genesis and maintenance of these disorders. However, mass media would exert a positive influence in the popularization of these entities to the general population that would result in a higher demand in general practice. PMID:11730579

  16. Psychiatric and substance use disorders in individuals with hepatitis C: epidemiology and management.

    Loftis, Jennifer M; Matthews, Annette M; Hauser, Peter

    2006-01-01

    Hepatitis C virus (HCV) infection is a major health concern in the US as well as in other countries worldwide. Treatment issues and disease management strategies are complicated by the extremely high rate of psychiatric and substance use disorders in those who have HCV. The majority of new and existing cases of HCV are related to injection drug use and, in this population, the prevalence of psychiatric comorbidity is high. Optimally, all patients with HCV should be screened for psychiatric and substance use disorders before initiation of antiviral therapy. If a patient screens positive, he or she should be referred to a mental healthcare provider or addiction specialist, assessed for the presence of a psychiatric or substance use disorder, and appropriately treated prior to initiation of antiviral (i.e. interferon) therapy. Although interferon-based therapies can lead to severe neuropsychiatric adverse effects, including in rare instances suicide, evidence suggests that many patients with comorbid psychiatric and substance use diagnoses can be treated safely and effectively using comanagement strategies. However, most patients with HCV are not treated with antiviral therapy. Therefore, we must expand our definition of HCV 'treatment' to include treatment of the comorbid psychiatric and substance use disorders that accompany HCV infection and precede antiviral therapy. This paper reviews the epidemiology and management of psychiatric and substance use disorders in patients with HCV, the issue of psychiatric and substance use disorders as contraindications for antiviral therapy, and current treatment strategies for HCV patients with these comorbid conditions. PMID:16451091

  17. Depressive and adjustment disorders – some questions about the differential diagnosis: case studies

    A Presicci

    2010-07-01

    Full Text Available A Presicci1, P Lecce1, P Ventura1, F Margari2, S Tafuri3, L Margari11Child Neuropsychiatric Unit, Department of Neurologic and Psychiatric Science, Aldo Moro University of Bari, Bari, Italy; 2Psychiatric Unit, Department of Neurologic and Psychiatric Science, Aldo Moro University of Bari, Bari, Italy; 3Hygiene Section, Department of Biomedical Science and Human Oncology, Aldo Moro University of Bari, Bari, ItalyBackground: Diagnosis and treatment of mood disorders in youth are still problematic because in this age the clinical presentation is atypical, and the diagnostic tools and the therapies are the same as that used for the adults. Mood disorders are categorically divided into unipolar disorders (major depressive disorder and dysthymic disorder and bipolar disorder in Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition, Text Revision, but mood symptoms are also comprised in the diagnostic criteria of the adjustment disorder (AD, which occur in many different psychiatric disorders, and may also be found in some physical conditions. The differential diagnosis is not much addressed in the midst of clinical ­investigation and so remains the major problem in the clinical practice.Aims: The associations between some variables and the depressive disorder and AD were analyzed to make considerations about differential diagnosis.Patients and methods: We reported a retrospective study of 60 patients affected by ­depressive disorder and AD. The analysis has evaluated the association between some variables and the single diagnostic categories. We have considered 10 variables, of which 6 are specific to the ­disorders, and 4 have been considered related problems.Results: The statistical analysis showed significant results for the associations of 3 variables (prevalent symptoms, treatment, and family history with the single diagnostic categories.Conclusion: The discriminate analysis resulted in statistically significant differences

  18. Genetic epidemiology and insights into interactive genetic and environmental effects in autism spectrum disorders.

    Kim, Young Shin; Leventhal, Bennett L

    2015-01-01

    Understanding the pathogenesis of neurodevelopmental disorders has proven to be challenging. Using autism spectrum disorder (ASD) as a paradigmatic neurodevelopmental disorder, this article reviews the existing literature on the etiological substrates of ASD and explores how genetic epidemiology approaches including gene-environment interactions (G×E) can play a role in identifying factors associated with ASD etiology. New genetic and bioinformatics strategies have yielded important clues to ASD genetic substrates. The next steps for understanding ASD pathogenesis require significant effort to focus on how genes and environment interact with one another in typical development and its perturbations. Along with larger sample sizes, future study designs should include sample ascertainment that is epidemiologic and population-based to capture the entire ASD spectrum with both categorical and dimensional phenotypic characterization; environmental measurements with accuracy, validity, and biomarkers; statistical methods to address population stratification, multiple comparisons, and G×E of rare variants; animal models to test hypotheses; and new methods to broaden the capacity to search for G×E, including genome-wide and environment-wide association studies, precise estimation of heritability using dense genetic markers, and consideration of G×E both as the disease cause and a disease course modifier. Although examination of G×E appears to be a daunting task, tremendous recent progress in gene discovery has opened new horizons for advancing our understanding of the role of G×E in the pathogenesis of ASD and ultimately identifying the causes, treatments, and even preventive measures for ASD and other neurodevelopmental disorders. PMID:25483344

  19. El papel de la epidemiología en la investigación de los trastornos mentales The role of epidemiology in mental disorder research

    Guilherme Borges

    2004-10-01

    , esta epidemiología también se orienta hacia un dominio particular de determinantes (como el uso, abuso o dependencia hacia las drogas y cómo estas variables independientes afectan determinados procesos y enfermedades (como los accidentes, el homicidio, el suicidio, la cirrosis hepática, etc. Por último, la epidemiología de los trastornos mentales se ha caracterizado también por su interés en una serie de procesos que no parecen constituir síndromes propiamente dichos, pero que son a todas luces de interés sanitario, siendo el ejemplo más claro de esto el problema de la violencia. La epidemiología de los trastornos mentales se enfrenta a enormes retos en el nuevo milenio. Debe hacer frente a un panorama epidemiológico complejo y cambiante. Los aspectos más importantes de su desarrollo futuro se vinculan con los siguientes puntos: medición de los trastornos mentales y de los factores de riesgo, el diseño y métodos de muestreo más eficientes, la relación entre la investigación biológica, la genética, las disciplinas sociales y la epidemiología, y la interfase entre la epidemiología y la evaluación de los tratamientos y los servicios.Mental disorders, including substance abuse, are part of the Mexican epidemiologic scenario and will remain so during several decades. They may even become more prominent as causes of disease, disability, and death in our country. It is thus imperative to frame appropriate management strategies to curb these problems without delay. This paper aims at outlining epidemiology of mental diseases as a field of study, and to identify its limitations. Emphasis is made on common elements shared with other more traditional fields of epidemiology, as well as on the specific contributions made by this particular field to epidemiology and to psychiatry in general. This paper describes the main study designs and problems in this field of epidemiology, its usefulness in prevention actions, and future challenges. A unique

  20. Epidemiology, health-related quality of life and economic burden of binge eating disorder: a systematic literature review

    Ágh, Tamás; Kovács, Gábor; Pawaskar, Manjiri; Supina, Dylan; Inotai, András; Vokó, Zoltán

    2015-01-01

    Purpose To perform a systematic review on the epidemiology, the health-related quality of life (HRQoL) and economic burden of binge eating disorder (BED). Methods A systematic literature search of English-language articles was conducted using Medline, Embase, PsycINFO, PsycARTICLES, Academic Search Complete, CINAHL Plus, Business Source Premier and Cochrane Library. Literature search on epidemiology was limited to studies published between 2009 and 2013. Cost data were inflated and converted ...

  1. Psychosocial Adjustment and Sibling Relationships in Siblings of Children with Autism Spectrum Disorder: Risk and Protective Factors

    Walton, Katherine M.; Ingersoll, Brooke R.

    2015-01-01

    This study compared sibling adjustment and relationships in siblings of children with Autism Spectrum Disorder (ASD-Sibs; n = 69) and siblings of children with typical development (TD-Sibs; n = 93). ASD-Sibs and TD-Sibs demonstrated similar emotional/behavioral adjustment. Older male ASD-Sibs were at increased risk for difficulties. Sibling…

  2. Estimating the prevalence of mental disorders in U.S. adults from the Epidemiologic Catchment Area Survey.

    Bourdon, K H; Rae, D S; Locke, B Z; Narrow, W.E.; Regier, D A

    1992-01-01

    The National Institute of Mental Health Epidemiologic Catchment Area Survey is a comprehensive, community-based survey of mental disorders and use of services by adults, ages 18 and older. Diagnoses are based on the criteria in the "Diagnostic and Statistical Manual of Mental Disorders," third edition, and were obtained in five communities in the United States through lay-interviewer administration of the National Institute of Mental Health Diagnostic Interview Schedule. Results from the surv...

  3. Demographic variables, clinical aspects, and medicolegal implications in a population of patients with adjustment disorder

    Anastasia A

    2016-04-01

    Full Text Available Annalisa Anastasia,1 Chiara Colletti,1 Valentina Cuoco,1 Adele Quartini,1 Stefania Urso,2 Raffaella Rinaldi,2 Giuseppe Bersani1 1Department of Medical-Surgical Sciences and Biotechnologies, Faculty of Pharmacy and Medicine, Sapienza University of Rome, 2Department of Anatomical, Istological, Forensic and Locomotor System Sciences, Sapienza University of Rome, Rome, Italy Introduction: Although adjustment disorder (AD is considered as residual diagnosis and receives little attention in research, it plays an important role in clinical practice and also assumes an increasingly important role in the field of legal medicine, where the majority of diagnostic frameworks (eg, mobbing often refer to AD. Our study aimed to look for specific stressor differences among demographic and clinical variables in a naturalistic setting of patients with AD.Methods: A restrospective statistical analysis of the data of patients diagnosed with AD from November 2009 to September 2012, identified via manual search from the archive of the outpatient setting at the University Unit of Psychiatry “A. Fiorini” Hospital, Terracina (Latina, Italy, was performed.Results: The sample consisted of 93 patients (46 males and 47 females, aged between 26 and 85, with medium–high educational level who were mainly employed. In most cases (54.80%, a diagnosis of AD with mixed anxiety and depressed mood was made. In all, 72% of the sample reported a negative family history for psychiatric disorders. In 22.60%, a previous history of psychopathology, especially mood disorders (76.19%, was reported. The main stressors linked to the development of AD were represented by working problems (32.30%, family problems (23.70%, and/or somatic disease (22.60% with significant differences with respect to age and sex. Half of the patients were subjected to a single first examination; 24.47% requested a copy of medical records.Conclusion: Confirming previous data from previous reports, our results

  4. Epidemiological and pathophysiological aspects of abdominal pain predominant functional gastrointestinal disorders in children and adolescents: a Sri Lankan perspective

    N.M. Devanarayana

    2015-01-01

    Abdominal pain-predominant functional gastrointestinal disorders (AP-FGIDs) are a worldwide pediatric problem with uncertain pathology. Main objectives of this thesis were to assess epidemiology, risk factors and underlying pathophysiological mechanisms of AP-FGIDs. A systematic review and meta-anal

  5. Epidemiological study of the prevalence of depressive disorders in primary health care in Morocco

    Bouchra Oneib

    2015-01-01

    Full Text Available Objective: To determine the prevalence and the impact of depressive disorders in primary health care and its associated factors. Methodology: It's a cross-sectional study with 351 participants selected from Moroccan primary care facilities, aged above 18 years without chronic somatic or psychiatric disease. The participants answered a questionnaire that included demographic characteristics, the Mini International Neuropsychiatric Interview for major depressive episode (MDE, dysthymic disorder and the Global Assessment of Functioning (GAF. Statistical analysis was performed by the SPSS 13.0 software. Results: The prevalence of depressive disorders in the sample was 13.7%, that of MDE was 9.1%, while dysthymic disorder was 4.3%, the rate of recurrent depressive episodes was 38.2% (6% of participants, and the prevalence of depression over a lifetime was 17.7%. The percentage of depression was higher among women than men (P = 0.01. 6.3% of depressed patients have already attempted to suicide. Analysis of GAF scores showed an average of 76.2 ± 24, a lower score was significantly found among patients with current MDE (P = 0.001, dysthymic subjects (P = 0.001 and those who suffer from recurrent MDE (P = 0.001. Depressive disorders in univariate analysis were associated with: Female gender P = 0.01 odds ratio (OR 2.1 (1.09–4.3, unemployment P = 0.02 OR 0.4 (0.2–0.9, and childbearing age P = 0.004 OR 3.5 (1.5–8. Adjusted OR has not demonstrated a significant association. Conclusion: The high prevalence of depressive disorders, suicide risk, and the alteration of the quality of life among primary health care patients in Morocco suggest the importance of identifying and treating this population.

  6. Advances in epidemiological study of post-traumatic stress disorders in postwar civilian survivors

    Xiang-yu KONG

    2012-02-01

    Full Text Available Post-traumatic stress disorder (PTSD is a feeling of persecution arising from the exposure to a life-threatening event. PTSD shows three kinds of characteristic symptoms including intrusive, avoidance, and arousal syndromes. Numerous literatures had been published on the study of the PTSD epidemiology. However, research results varied due to different research subjects and evaluation methods used. A big difference exists between the studies on refugees, migrating population, and community population, because these studies are affected by different definitions of war trauma, difference in choice of samples, and application of psychological intervention. Therefore, no exact conclusions have been established on the accurate incidence of PTSD in civilians after having endured war trauma or mental torture. Currently, studies on PSTD are still inadequate. The first reason for this inadequacy is the difference existing between previous study methods. In addition, differences also exist in the statistical results between different research groups; the present study objects are all non-western ethnics or some specific population, thus selective bias existing in samples adopted. Secondly, the majority of the studies had no a control group, thus the results lacking reliability and universality. The third reason is that more attention should be paid to the impact of nationality and cultural background on the study of postwar PTSD. In summary, a large amount of work should be done in the field of PSTD epidemiology in the future. Therefore, it is very important to look for simple tools for screening and measuring PTSD in Chinese population, and investigate the incidence of PTSD after all kinds of traumatic events and its distribution for effectively preventing and treating PTSD.

  7. Comparison of Memory Function and MMPI-2 Profile between Post-traumatic Stress Disorder and Adjustment Disorder after a Traffic Accident

    Bae, Sung-Man; Hyun, Myoung-Ho; Lee, Seung-Hwan

    2014-01-01

    Objective Differential diagnosis between post-traumatic stress disorder (PTSD) and adjustment disorder (AD) is rather difficult, but very important to the assignment of appropriate treatment and prognosis. This study investigated methods to differentiate PTSD and AD. Methods Twenty-five people with PTSD and 24 people with AD were recruited. Memory tests, the Minnesota Multiphasic Personality Inventory 2 (MMPI-2), and Beck's Depression Inventory were administered. Results There were significan...

  8. Learning, Adjustment and Stress Disorders: With Special Reference to Tsunami Affected Regions. Beitrage zur Padagogischen und Rehabilitationspsychologie. Volume 1

    Witruk, Evelin, Ed.; Riha, David, Ed.; Teichert, Alexandra, Ed.; Haase, Norman, Ed.; Stueck, Marcus, Ed.

    2010-01-01

    This book contains selected contributions from the international workshop Learning, "Adjustment and Stress Disorders--with special reference to Tsunami affected Regions" organised by Evelin Witruk and the team of Educational and Rehabilitative Psychology at the University of Leipzig in January 2006. The book contains new results and the state of…

  9. Adjustment Difficulties and Caregiving Burdens Faced by College Students with a Parent with Bipolar or Depressive Disorders

    Crandall, Erin K.; Ruggero, Camilo J.; Bain, Kathleen; Kilmer, Jared

    2014-01-01

    College campuses often host students who come from families where one or more parent has been affected by a bipolar or depressive disorder. The present study sought to determine whether these students face unique challenges in college, including increased adjustment difficulties as well as greater caregiving burden associated with their…

  10. Reducing long term sickness absence by an activating intervention in adjustment disorders: a cluster randomised controlled design

    Klink, van der, J.; Blonk, R.W B; Schene, A.H.; Dijk, van, B.W.

    2003-01-01

    Aims: To compare an innovative activating intervention with "care as usual" (control group) for the guidance of employees on sickness leave because of an adjustment disorder. It was hypothesised that the intervention would be more effective than care as usual in lowering the intensity of symptoms, increasing psychological resources, and decreasing sickness leave duration.

  11. The Epidemiology of Alcohol Use and Alcohol Use Disorders among Young People in Northern Tanzania.

    Joel M Francis

    Full Text Available Alcohol use is a global public health problem, including as a risk factor for HIV infection, but few data are available on the epidemiology of alcohol use and alcohol use disorders (AUD among young people in sub-Saharan Africa.We conducted a cross-sectional survey among 4 groups of young people aged 15-24 years old (secondary school students, college/university students, employees of local industries and casual labourers in two regions (Kilimanjaro and Mwanza of northern Tanzania. Using a multistage stratified random sampling strategy, we collected information on demographics, alcohol use, and behavioural factors. We screened severity of alcohol use using the Alcohol Use Disorder Identification Test (AUDIT and estimated the quantity and frequency of alcohol consumption using the timeline-follow-back-calendar (TLFB method.A total of 1954 young people were surveyed. The prevalence of reported alcohol use was higher among males (47-70% ever users and 20-45% current users than females (24-54% ever users and 12-47% current users. Prevalence of use was substantially higher in Kilimanjaro than Mwanza region. In both regions, participants reported high exposure to alcohol advertisements, and wide alcohol availability. College students reported the highest prevalence of current alcohol use (45% among males; 26% among females and of heavy episodic drinking (71% among males; 27% among females followed by casual labourers. Males were more likely to have AUD (an AUDIT score ≥8 than females, with 11-28% of males screening positive for AUD. Alcohol use was associated with male gender, being in a relationship, greater disposable income, non-Muslim religion and a higher number of sexual partners.Alcohol use is a significant problem among young people in northern Tanzania. There is an urgent need to develop, pilot and deliver interventions to help young people delay initiation and reduce levels of harmful drinking, particularly among college students and casual

  12. Obsessive-compulsive disorder in the perinatal period: epidemiology, phenomenology, pathogenesis, and treatment

    Álvaro Frías

    2015-01-01

    Full Text Available The aim of this review is to describe the main theoretical findings and research conclusions about obsessive-compulsive disorder (OCD in the perinatal period. On one hand, epidemiological studies show that the risk of OCD onset and/or exacerbation could increase in this period, particularly in the puerperium. Phenomenologically, in this stage aggressive and contamination obsessions are very common and are related to the fetus or newborn. On the other hand, regarding OCD pathogenesis in this period, there is indirect evidence to suggest the participation of neuroendocrine (e.g. female gonadal steroids and oxytocin and cognitive behavioural variables (e.g. hyper-responsibility, threat overestimation, and mental control. In terms of research, more empirical studies are needed to contrast these specific vulnerability factors. Moreover, no empirically validated psychotherapeutic treatments (controlled trials adapted to this OCD sub-group were found, although some studies highlight the role of cognitive behavioural therapy (CBT as an effective intervention in the context of selective primary prevention.

  13. Drug use disorders in the polydrug context: new epidemiological evidence from a foodborne outbreak approach.

    Lopez-Quintero, Catalina; Anthony, James C

    2015-09-01

    As epidemiologists studying foodborne illness outbreaks, we do not ask luncheon attendees to say which food caused their illnesses. Instead, we use measurement and analysis methods to estimate food-specific risk variations. Here, we adapt the foodborne outbreak approach to develop new estimates of drug use disorder risk for single-drug and polydrug users, without attributing the syndrome to a specific drug when multiple drugs have been used. We estimate drug use disorder risk for cannabis-only users as a reference value. We then derive comparative relative risk estimates for users of other drug subtypes, including polydrug combinations. Data are from the 2002 to 2003 U.S. National Comorbidity Survey Replication, a nationally representative sample of household residents (18+ years), with standardized drug use and drug dependence assessments. Multiple logistic regression provides odds ratio estimates of relative risk. With this approach, for every 1000 cannabis-only users, an estimated 17 had become cases (1.7%). By comparison, polydrug users and cocaine-only users had much greater cumulative incidence (>10%), even with adjustment for covariates and local area matching (P < 0.001). Using this approach, we find exceptionally low risk for cannabis-only users and greater risk for polydrug and cocaine-only users. PMID:26348487

  14. Epidemiologia, curso e evolução dos transtornos alimentares Epidemiology, course and evolution of eating disorders

    Vanessa Pinzon

    2004-01-01

    Full Text Available Os transtornos alimentares costumam afetar mulheres jovens e ter curso crônico, variável e com alto grau de morbidade e mortalidade. Este artigo visa a apresentar os dados que suportam tais impressões clínicas.Eating disorders use to affect young women and have a chronic and variable course, with high levels of morbidity and mortality. The objective of this article is to demonstrate the epidemiological findings that support such clinical impressions.

  15. Intimate partner violence and specific substance use disorders: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions

    Smith, Philip H.; Homish, Gregory G.; Leonard, Kenneth E.; Cornelius, Jack R.

    2011-01-01

    The association between substance use and intimate partner violence (IPV) is robust. It is less clear how the use of specific substances relates to relationship violence. This study examined IPV perpetration and victimization related to the following specific substance use disorders: alcohol, cannabis, cocaine and opioid. The poly-substance use of alcohol and cocaine, as well as alcohol and marijuana were also examined. Data were analyzed from wave two of the National Epidemiologic Study on A...

  16. Psycho-trauma, psychosocial adjustment and symptomatic Post-traumatic stress disorder among internally displaced persons in Kaduna, Northwestern Nigeria

    Taiwo Lateef Sheikh; Abdulaziz eMohammed; Samuel eAgunbiade; Joseph eIke; Ebiti, William N.; Oluwatosin eAdekeye

    2014-01-01

    Background In April 2011, a post election violent conflict in Northern Nigeria led to resettlement of internally displaced persons (IDPs) in a camp in Kaduna, the worst affected state. We set out to determine prevalence and socio-demographic factors associated with post-traumatic stress disorder (PTSD) among IDPs. We also determined types of psycho-trauma experienced by the IDPs and their psychosocial adjustment.MethodsCross-sectional systematic random sampling was used to select 258 adults I...

  17. A Follow-up Study of Academic Functioning and Social Adjustment in Children with Attention Deficit Hyperactivity Disorder

    Jasmin Garg; Priti Arun

    2013-01-01

    Background : Attention deficit hyperactivity disorder (ADHD) persists in a majority of adolescents. It has been reported that ADHD patients have poor social functioning and risk for developing co-morbid psychiatric illnesses. Aims: To determine the retention of diagnosis of ADHD and to assess social adjustment, academic functioning and co-morbidities at follow-up. Design: Retrospective cohort study. Materials and Methods: ADHD patients of 5-14 years of age who came to the out-patient departme...

  18. Geriatric teaching in Brazilian medical schools in 2013 and considerations regarding adjustment to demographic and epidemiological transition

    Ana Conceição Norbim Prado Cunha

    2016-04-01

    Full Text Available Summary Objective: This study aims to describe the profile of medical schools that introduced courses on Geriatrics and Elderly Health or Aging in their curriculum, and compare such information with the age distribution and health epidemiological data of the Brazilian population, using data until the year of 2013. Methods: 180 universities offering medical undergraduate courses and registered with the Ministry of Education and Culture of Brazil (MEC were found, as seen on the MEC website (www.emec.mec.gov.br in February 2013. Based on the list of institutions, the authors created a database. Results: Brazil's Southeast region is the one presenting most of the courses, both offered as core or elective subjects, in the area of Geriatrics. The Midwest region had the least offer of Geriatrics and Elderly Health and Care courses. The Southeast region presents the greater absolute number of institutions with elective subjects, followed by the South and Northeast regions, each with a single institution. The Southeast region was at the same time the one that presented the biggest absolute number of institutions offering core subjects in the area of Geriatrics, being followed by the Northeast, South, North, and Midwest regions. Conclusion: By analyzing the availability of courses that emphasize aging and Geriatrics in brazilian medical schools, the present study reveals that specialized training should be encouraged with respect to the specificities of health care given to the elderly population, which has a higher frequency of chronic and degenerative diseases.

  19. Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings: a meta-analysis of 94 interview-based studies

    Mitchell, A. J.; Chan, M.; Bhatti, H.;

    2011-01-01

    Background Substantial uncertainty exists about prevalence of mood disorders in patients with cancer, including those in oncological, haematological, and palliative-care settings. We aimed to quantitatively summarise the prevalence of depression, anxiety, and adjustments disorders in these settings....... Methods We searched Medline, PsycINFO, Embase, and Web of Knowledge for studies that examined well-defined depression, anxiety, and adjustment disorder in adults with cancer in oncological, haematological, and palliative-care settings. We restricted studies to those using psychiatric interviews. Studies...... Mental Disorders (DSM) or International Classification of Diseases (ICD) criteria was 16.5% (95% CI 13.1-20.3), 14.3% (11.1-17-9) for DSM-defined major depression, and 9.6% (3.6-18.1) for DSM-defined minor depression. Prevalence of adjustment disorder alone was 15.4% (10.1-21.6) and of anxiety disorders...

  20. Prevalence of mood and anxiety disorder in self reported irritable bowel syndrome (IBS. An epidemiological population based study of women

    Mykletun Arnstein

    2010-08-01

    Full Text Available Abstract Background Irritable bowel syndrome (IBS is commonly regarded as a functional disorder, and is hypothesized to be associated with anxiety and depression. This evidence mainly rests on population-based studies utilising self-report screening instruments for psychopathology. Other studies applying structured clinical interviews are generally based on small clinical samples, which are vulnerable to biases. The extant evidence base for an association between IBS and psychopathology is hence not conclusive. The aim of this study was therefore to re-examine the hypothesis using population-based data and psychiatric morbidity established with a structured clinical interview. Methods Data were derived from a population-based epidemiological study (n = 1077. Anxiety and mood disorders were established using the Structured Clinical Interview for DSM-IV-TR (SCID-I/NP and the General Health Questionnaire (GHQ-12. Current and lifetime IBS was self-reported. Hypertension and diabetes were employed as comparison groups as they are expected to be unrelated to mental health. Results Current IBS (n = 69, 6.4% was associated with an increased likelihood of current mood and/or anxiety disorders (OR = 2.62, 95%CI 1.49 - 4.60. Half the population reporting a lifetime IBS diagnosis also had a lifetime mood or anxiety disorder. Exploratory analyses demonstrated an increased prevalence of IBS across most common anxiety and mood disorders, the exception being bipolar disorder. The association with IBS and symptoms load (GHQ-12 followed a curved dose response pattern. In contrast, hypertension and diabetes were consistently unrelated to psychiatric morbidity. Conclusions IBS is significantly associated with anxiety and mood disorders. This study provides indicative evidence for IBS as a disorder with a psychosomatic aspect.

  1. Differences in adjustment by child developmental stage among caregivers of children with disorders of sex development

    Hullmann Stephanie E; Fedele David A; Wolfe-Christensen Cortney; Mullins Larry L; Wisniewski Amy B

    2011-01-01

    Abstract Background The current study sought to compare levels of overprotection and parenting stress reported by caregivers of children with disorders of sex development at four different developmental stages. Methods Caregivers (N = 59) of children with disorders of sex development were recruited from specialty clinics and were asked to complete the Parent Protection Scale and Parenting Stress Index/Short Form as measures of overprotective behaviors and parenting stress, respectively. Resul...

  2. What kind of diagnosis in a case of mobbing: post-traumatic stress disorder or adjustment disorder?

    Signorelli, Maria Salvina; Costanzo, Maria Cristina; Cinconze, Maria; Concerto, Carmen

    2013-01-01

    Over the last decade a consistent increase in stress-related psychological consequences at the workplace, usually called 'mobbing', has been seen. It claimed physical, psychical and social distress as its victims, leading to an increased incidence of many illnesses, such as psychosomatic disorders (ache, high blood pressure, chronic fatigue and insomnia) and psychiatric disturbances (high level of anxiety, depression and suicidal attempts). It was recently demonstrated that mobbing is significantly widespread among healthcare workers, especially among female nurses. In this report, we illustrate the case of a nurse who, after a brilliant career, underwent mobbing at the workplace, showing depression, anxiety and sleep disorders that required hospitalisation and a substantial intervention. PMID:23761569

  3. What kind of diagnosis in a case of mobbing: post-traumatic stress disorder or adjustment disorder?

    Signorelli, Maria Salvina; Costanzo, Maria Cristina; Cinconze, Maria; Concerto, Carmen

    2013-01-01

    Over the last decade a consistent increase in stress-related psychological consequences at the workplace, usually called ‘mobbing’, has been seen. It claimed physical, psychical and social distress as its victims, leading to an increased incidence of many illnesses, such as psychosomatic disorders (ache, high blood pressure, chronic fatigue and insomnia) and psychiatric disturbances (high level of anxiety, depression and suicidal attempts). It was recently demonstrated that mobbing is signifi...

  4. [Epidemiology of drug addiction and historical cycles of other psychic disorders].

    Sardi, P A

    1981-09-26

    Through observation of the late complete cycle of diffusion of Great Hysteria we may get a confrontation with the present epidemiological diffusion of drug dependence. Of the different cycles is here showed a structural analysis, based on the hypothesis of alternated repression of Eros and Thanatos, with the respective returns of the sexual and aggressive repressed instincts. PMID:7024851

  5. [Body dysmorphic disorder. Epidemiology, clinical symptoms, classification and differential treatment indications: an overview].

    Driesch, Georg; Burgmer, Markus; Heuft, Gereon

    2004-09-01

    Body dysmorphic disorder (BDD), also known as dysmorphophobia, is a relatively common disorder that consists of preoccupation with some imagined or slight defect in physical appearance. The preoccupation causes emotional distress and social impairment. Overvalued ideation and referential thinking are prevalent. BDD has a rich tradition in European psychiatry, but it first entered the official psychiatric nomenclature as a separate disorder in DSM-III-R in 1987. In the last 10 years it has received increasing empirical attention. BDD has been hypothesized to be related to obsessive-compulsive disorder (OCD) or may be conceptualized as hypochondriacal disorder. According to its body image disturbance it has been related to cenesthesia, eating disorders, and transsexualism. This paper presents the current level of awareness about BDD based on an analysis of the relevant literature. Empirical data are summarized and clinical signs are described. Varying therapies are critically reviewed. PMID:15316620

  6. Eating disorders behaviours and diagnoses: epidemiology and comorbidity in the general population

    Solmi, F.

    2014-01-01

    Introduction: Studies investigating prevalence and comorbidity of eating disorders (ED) and disordered eating in large general population samples are limited. This thesis adds to the existing literature by employing general population studies to investigate prevalence and comorbidity of disordered eating and ED in adults and adolescents. Secondary aims were to explore occurrence of ED in relation to ethnicity and patterns of service use. Methods: The studies included in this thesis employed t...

  7. Eating disorders of infancy and childhood: definition, symptomatology, epidemiology, and comorbidity.

    Nicholls, Dasha; Bryant-Waugh, Rachel

    2009-01-01

    This article describes a range of problem feeding and eating presentations seen in infants and children. In diagnostic terms some fall under the category of "feeding disorder," whereas others are childhood presentations of the eating disorders "anorexia nervosa," "bulimia nervosa," and atypical forms of these. Several other commonly occurring presentations that are difficult to fit into existing diagnostic categories are additionally described here, including "selective eating," "food avoidance emotional disorder," "food phobias," "functional dysphagia," and "food refusal." PMID:19014855

  8. Prevalence of Child and Adolescent Mental Disorders in Chile: A Community Epidemiological Study

    Vicente, Benjamin; Saldivia, Sandra; de la Barra, Flora; Kohn, Robert; Pihan, Ronaldo; Valdivia, Mario; Rioseco, Pedro; Melipillan, Roberto

    2012-01-01

    Background: In Latin America, there is limited research on the prevalence of mental disorders in children and adolescents. This Chilean survey is the first national representative survey in the Latin American region to examine the prevalence of Diagnostic and Statistical Manual-IV (DSM-IV) psychiatric disorders in the region in children and…

  9. Psycho-trauma, psychosocial adjustment and symptomatic Post-traumatic stress disorder among internally displaced persons in Kaduna, Northwestern Nigeria

    Taiwo Lateef Sheikh

    2014-09-01

    Full Text Available Background In April 2011, a post election violent conflict in Northern Nigeria led to resettlement of internally displaced persons (IDPs in a camp in Kaduna, the worst affected state. We set out to determine prevalence and socio-demographic factors associated with post-traumatic stress disorder (PTSD among IDPs. We also determined types of psycho-trauma experienced by the IDPs and their psychosocial adjustment.MethodsCross-sectional systematic random sampling was used to select 258 adults IDPs. We used Harvard trauma questionnaire to diagnose symptomatic PTSD, composite international diagnostic interview for diagnosis of depression, and communal trauma event inventory to determine exposure to psycho-trauma. We assessed social adjustment using social provision scale. Multiple logistic regression was used to determine independent predictors of PTSD. Results Of the 258 IDPs, 109 (42.2% had a diagnosis of PTSD, 204 (79.1% had poor living conditions, and only12 (4.7% had poor social provision. The most frequent psycho-traumas were destruction of personal property (96.1%, been evacuated from their town (96% and witnessing violence (88%. More than half (58% of IDPs had experienced 11 – 15 of the 19 traumatic events. Independent predictors of PTSD among respondents were, having a CIDI diagnosis of depression (Adjusted Odd Ratio [AOR]3.5, 95% CI 1.7 – 7.5; p= 0.001 and witnessing death of a family member ( 3.7, 1.2 – 11.5; p=0.0259.ConclusionWe concluded that exposure to psycho-trauma among IDPs in Kaduna led to post conflict PTSD. Death of a family member and co-morbid depression were independent predictors of PTSD among IDPs. Though their living condition was poor, the IDPs had good psychosocial adjustment. We recommended a structured psychosocial intervention among the IDP targeted at improving living condition and dealing with the psychological consequences of psycho-trauma.Key words Post traumatic stress disorder, psychosocial adjustment

  10. A follow-up study of academic functioning and social adjustment in children with attention deficit hyperactivity disorder

    Jasmin Garg

    2013-01-01

    Full Text Available Background : Attention deficit hyperactivity disorder (ADHD persists in a majority of adolescents. It has been reported that ADHD patients have poor social functioning and risk for developing co-morbid psychiatric illnesses. Aims: To determine the retention of diagnosis of ADHD and to assess social adjustment, academic functioning and co-morbidities at follow-up. Design: Retrospective cohort study. Materials and Methods: ADHD patients of 5-14 years of age who came to the out-patient department from 2005 to 2008 were contacted telephonically. Fifty one patients could be contacted. Parents of patients were interviewed using Vanderbilt ADHD Diagnostic Parent Rating Scale for diagnosing ADHD and co-morbidities. Social Adjustment Inventory for Children and Adolescent was administered for assessing their academic and social functioning. Chi square test, Mann-Whitney Test, Kruskal-Wallis Test, and Pearson′s product moment correlations were used for statistical analysis. Results: At current assessment, out of 51 patients, 38 were still fulfilling diagnosis of ADHD. Of these, 21 were of inattention type, 3 were hyperactive, and 14 were of combined type. Social functioning and academic functioning were significantly better in those who currently did not fulfill the criteria for ADHD ( N=13. Twelve patients developed features of oppositional defiant disorder (ODD/conduct disorder (CD at follow-up. Conclusions: ADHD persists in the majority of adolescents. Decline with age is seen more in hyperactive/impulsive symptoms than inattentive symptoms. Several adolescents also develop features of ODD/CD in addition to poorer functioning. Continuation of treatment is crucial to prevent such consequences.

  11. Epidemiology, neurobiology and pharmacological interventions related to suicide deaths and suicide attempts in bipolar disorder

    Schaffer, Ayal; Isometsä, Erkki T; Tondo, Leonardo;

    2015-01-01

    pharmacotherapy studies specific to bipolar disorder. We conducted pooled, weighted analyses of suicide rates. RESULTS: The pooled suicide rate in bipolar disorder is 164 per 100,000 person-years (95% confidence interval = [5, 324]). Sex-specific data on suicide rates identified a 1.7:1 ratio in men compared to...... associations with suicide attempts and deaths in bipolar disorder, but few replication studies. Data on treatment with lithium or anticonvulsants are strongly suggestive for prevention of suicide attempts and deaths, but additional data are required before relative anti-suicide effects can be confirmed. There...... were limited data on potential anti-suicide effects of treatment with antipsychotics or antidepressants. CONCLUSION: This analysis identified a lower estimated suicide rate in bipolar disorder than what was previously published. Understanding the overall risk of suicide deaths and attempts, and the...

  12. [Sleep and sleep disorders in the elderly: Part 1: epidemiology and diagnostics].

    Frohnhofen, H; Schlitzer, J

    2014-08-01

    Restorative sleep is an important factor for well-being, performance and quality of life. The basic diagnostic procedure of a sleep disorder is to take a comprehensive sleep history. Sleep disorders can and must be distinguished from the physiological changes of sleep in the elderly. Insomnia (difficulty in sleeping), daytime sleepiness (hypersomnia), sleep-related breathing disorders (SRBD) and movement disorders during sleep are also common in the elderly. They must be detected because they are treatable and can dominate the clinical picture of geriatric syndromes. Nursing home residents and dementia patients are in particular need of attention as their sleep is often adversely affected by the living environment and the daily institutional routine. PMID:25117857

  13. Epidemiological associations between brachycephaly and upper respiratory tract disorders in dogs attending veterinary practices in England

    O’Neill, Dan G; Jackson, Caitlin; Guy, Jonathan H.; Church, David B.; McGreevy, Paul D.; Thomson, Peter C.; Brodbelt, Dave C.

    2015-01-01

    Background Brachycephalic dog breeds are increasingly common. Canine brachycephaly has been associated with upper respiratory tract (URT) disorders but reliable prevalence data remain lacking. Using primary-care veterinary clinical data, this study aimed to report the prevalence and breed-type risk factors for URT disorders in dogs. Results The sampling frame included 170,812 dogs attending 96 primary-care veterinary clinics participating within the VetCompass Programme. Two hundred dogs were...

  14. Epidemiology, Comorbidity, and Behavioral Genetics of Antisocial Personality Disorder and Psychopathy

    Werner, Kimberly B.; Few, Lauren R.; Bucholz, Kathleen K.

    2015-01-01

    Psychopathy is theorized as a disorder of personality and affective deficits while antisocial personality disorder (ASPD) diagnosis is primarily behaviorally based. While ASPD and psychopathy are similar and are highly comorbid with each other, they are not synonymous. ASPD has been well studied in community samples with estimates of its lifetime prevalence ranging from 1-4% of the general population.4,5 In contrast, psychopathy is almost exclusively investigated within criminal populations s...

  15. Successful interventions on an organisational level to reduce violence and coercive interventions in in-patients with adjustment disorders and personality disorders

    Goeser Ulla

    2008-11-01

    Full Text Available Abstract Background Self-directed and other violence as well as subsequent coercive interventions occur in a substantial proportion of patients with personality disorders during in-patient treatment. Different strategies may be required to reduce coercive interventions for patients of different diagnostic groups. Methods We specialised one of our acute admission wards in the treatment of personality disorders and adjustment disorders (ICD-10 F4 and F6. Patients are not transferred to other acute wards in case of suicidal or violent behaviour. Violent behaviour and coercive interventions such as seclusion or restraint were recorded in the same way as in the rest of the hospital. We recorded the percentage of subjects affected by diagnostic group and average length of an intervention in the year before and after the change in organisational structure. Results The total number of coercive interventions decreased by 85% both among patients with an F4 and those with an F6 primary diagnosis. Violent behaviours decreased by about 50%, the proportion of involuntary committed patients decreased by 70%. Conclusion The organisational change turned out to be highly effective without any additional cost of personnel or other resources.

  16. Epidemiology, course and outcome of acute polymorphic psychotic disorder: implications for ICD-11

    Castagnini, Augusto; Foldager, Leslie

    2014-01-01

    concepts of bouffée délirante and cycloid psychosis. Sampling and Methods: We selected all subjects aged 15-64 years (n = 5,426) who were listed in the Danish Psychiatric Central Register with a first-admission diagnosis of ATPDs in 1995-2008 and estimated incidence rates, course and outcome up to 2010...... schizophrenic or predominantly delusional symptoms. Acute polymorphic psychotic disorder was more common in females, while cases with acute schizophrenic features predominated in younger males and evolved more often into schizophrenia and related disorders. Conclusions: These findings suggest that acute...

  17. Interrater agreement for the schedule for affective disorders and schizophrenia epidemiological version for school-age children (K-SADS-E

    Polanczyk Guilherme V

    2003-01-01

    Full Text Available OBJETIVE: The main objective of this study was to assess the interrater agreement for the Schedule for Affective Disorders and Schizophrenia Epidemiological version for School-Age Children (K-SADS-E. METHODS: Four interviewers being trained with the K-SADS-E scored independently 29 videotaped interviews performed with psychiatric outpatients in the ADHD Outpatient Clinic at Hospital de Clínicas de Porto Alegre. Interrater agreement analysis was performed using the kappa coefficient (k. RESULTS: Kappa coefficients were .93 (p<.001 for affective disorders, .9 (p<.001 for anxiety disorders, .94 (p<.001 for attention-deficit/hyperactivity disorders and disruptive behavior disorders. CONCLUSION: These findings suggest an excellent interrater agreement for the diagnosis of several mental disorders in childhood and adolescence by the Brazilian Portuguese version of the K-SADS-E.

  18. Determinants of Psychosocial Difficulties Experienced by Persons with Brain Disorders: Towards a 'Horizontal Epidemiology' Approach.

    Carla Sabariego

    Full Text Available Persons with brain disorders experience significant psychosocial difficulties (PSD in daily life, e.g. problems with managing daily routine or emotional lability, and the level of the PSD depends on social, physical and political environments, and psychologic-personal determinants. Our objective is to determine a brief set of environmental and psychologic-personal factors that are shared determinants of PSD among persons with different brain disorders.Cross-sectional study, convenience sample of persons with either dementia, stroke, multiple sclerosis, epilepsy, migraine, depression, schizophrenia, substance dependence or Parkinson's disease. Random forest regression and classical linear regression were used in the analyses.722 subjects were interviewed in four European countries. The brief set of determinants encompasses presence of comorbidities, health status appraisal, stressful life events, personality changes, adaptation, self-esteem, self-worth, built environment, weather, and health problems in the family.The identified brief set of common determinants of PSD can be used to support the implementation of cross-cutting interventions, social actions and policy tools to lower PSD experienced by persons with brain disorders. This set complements a recently proposed reliable and valid direct metric of PSD for brain disorders called PARADISE24.

  19. Epidemiology of Autism Spectrum Disorder in Portugal: Prevalence, Clinical Characterization, and Medical Conditions

    Oliveira, Guiomar; Ataide, Assuncao; Marques, Carla; Miguel, Teresa S.; Coutinho, Ana Margarida; Mota-Vieira, Luisa; Goncalves, Esmeralda; Lopes, Nazare Mendes; Rodrigues, Vitor; Carmona da Mota, Henrique; Vicente, Astrid Moura

    2007-01-01

    The objective of this study was to estimate the prevalence of autistic spectrum disorder (ASD) and identify its clinical characterization, and medical conditions in a paediatric population in Portugal. A school survey was conducted in elementary schools, targeting 332 808 school-aged children in the mainland and 10 910 in the Azores islands.…

  20. Development of a Protocol for Epidemiologal Studies of Whole-Body Vibration and Musculoskeletal Disorders of the Lower Back

    Magnusson, M. L.; Pope, M. H.; Hulshof, C. T. J.; Bovenzi, M.

    1998-08-01

    It seems evident from a large number of studies that there is a positive relationship between exposure to whole body vibration (WBV) and the occurrence of low back pain. There are existing standards for evaluating the human exposure to WBV, which are based on other factors than the effect of musculoskeletal disorders. Several national and international standards also exist for evaluating human exposure to WBV. The exposure limit values or health guidance caution zones included in some of these standards are not or only to a limited extent based on systematic epidemiological investigations. It has not yet been possible to establish a clear exposure-response relationship. There are many confounding or contributing factors which influence the hazards to workers caused by exposure to WBV. Reliable methods for the detection and prevention of injury due to vibration exposure at work, alone or in combination with other risk factors, need to be implemented. The aim of this paper was to design a protocol and a questionnaire for conducting collaborative studies of WBV and musculoskeletal back disorders. The protocol will be tested in a pilot study before it will be used in multi-center studies.

  1. Psycho-Trauma, Psychosocial Adjustment, and Symptomatic Post-Traumatic Stress Disorder among Internally Displaced Persons in Kaduna, Northwestern Nigeria

    Sheikh, Taiwo Lateef; Mohammed, Abdulaziz; Agunbiade, Samuel; Ike, Joseph; Ebiti, William N.; Adekeye, Oluwatosin

    2014-01-01

    Background: In April 2011, a post election violent conflict in Northern Nigeria led to resettlement of internally displaced persons (IDPs) in a camp in Kaduna, the worst affected state. We set out to determine prevalence and socio-demographic factors associated with post-traumatic stress disorder (PTSD) among IDPs. We also determined types of psycho-trauma experienced by the IDPs and their psychosocial adjustment. Methods: Cross-sectional systematic random sampling was used to select 258 adults IDPs. We used Harvard trauma questionnaire to diagnose “symptomatic PTSD,” composite international diagnostic interview (CIDI) for diagnosis of depression, and communal trauma event inventory to determine exposure to psycho-trauma. We assessed social adjustment using social provision scale. Multiple logistic regression analysis was used to determine independent predictors of PTSD. Results: Of the 258 IDPs, 109 (42.2%) had a diagnosis of PTSD, 204 (79.1%) had poor living conditions, and only 12 (4.7%) had poor social provision. The most frequent psycho-traumas were destruction of personal property (96.1%), been evacuated from their town (96%) and witnessing violence (88%). More than half (58%) of IDPs had experienced 11–15 of the 19 traumatic events. Independent predictors of PTSD among respondents were having a CIDI diagnosis of depression (adjusted odds ratios 3.5, 95% confidence interval 1.7–7.5; p = 0.001) and witnessing death of a family member (3.7, 1.2–11.5; p = 0.0259). Conclusion: We concluded that exposure to psycho-trauma among IDPs in Kaduna led to post conflict PTSD. Death of a family member and co-morbid depression were independent predictors of PTSD among IDPs. Though their living condition was poor, the IDPs had good psychosocial adjustment. We recommended a structured psychosocial intervention among the IDP targeted at improving living condition and dealing with the psychological consequences of psycho-trauma. PMID:25309461

  2. Tobacco Smoking in Individuals with Attention-Deficit/Hyperactivity Disorder: Epidemiology and Pharmacological Approaches to Cessation

    Gray, Kevin M.; Upadhyaya, Himanshu P.

    2009-01-01

    The co-occurrence of Attention-Deficit/Hyperactivity Disorder (ADHD) and Nicotine Dependence is common. Individuals with ADHD are more likely to initiate smoking and become dependent on nicotine than their non-ADHD counterparts, and recent evidence suggests that they may have more difficulty quitting smoking. Little is known about how to best approach treating these co-morbidities to optimize clinical outcome. Clinicians treating individuals with either ADHD or Nicotine Dependence should be a...

  3. Temporomandibular disorders among Sami women : perspectives based on an epidemiological survey with mixed methods

    Storm Mienna, Christina

    2014-01-01

    Introduction The aim of the research project was to examine prevalence, co-morbidity, and impact on daily life of pain and dysfunction in the jaw-face, head, and neck-shoulder regions among adult Sami women in northern Sweden. The aim of the qualitative part of the study was to explore, thoughts, experiences, and beliefs regarding temporomandibular disorders (TMD) among Sami women with and without TMD, to gain insights into their health care experiences. Methods The research project used a mi...

  4. [Reactive anxiety crisis and chronic adjustment disorder: a unique case of work injury and suspected occupational disease].

    Taino, Giuseppe; Pizzuto, Cristina; Pezzuto, Cristina; Pucci, Ennio; Imbriani, Marcello

    2014-01-01

    The present study aims to describe a case of work injury and occupational disease which is unique for the type of disease diagnosed, conditions of onset and mode of management by INAIL (Italian National Institute of Insurance for Injuries at Work and Occupational Diseases). A worker, after a verbal animated dispute with some collegues and superiors, had an acute psychiatric agitation attack and went to the nearest emergency room, where he was subjected to clinical exams. No neuropsychiatric alteration was found, but the physicians diagnosed an anxiety crisis reactive to the work environment. Consequently, the medical certificate for work injury was edited and sent to INAIL. The worker has been off work for 110 days because of a anxious and depressive syndrome, due to the verbal conflict. In a later assessment, INAIL recognized only the first 30 days of the employee's time off as injury at work, while judging the following period off work as related to affectivity disturbance due to common disease, not related to work environment. The following year, "anxious-depressive syndrome" is worsened and attributed by the same worker to the recurrence of acts of persecution and discrimination against him at work. For this reason he applied for recognition of occupational disease diagnosed as "Chronic Adjustment Disorder with prolonged depressive reaction and somatic anxiety, which developed into a protracted conflict marked the employment situation". INAIL rejected that request, but in the same year the employee has submitted the complaint for "mobbing". Even this request was rejected. Literature shows many examples of traumatic events during working activities which cause psychiatric disturbances. These events include industrial disasters, explosions, transport and mining accidents, accidents in psychiatric units with high risks of assaults, armed conflicts, war, assault and sexual assault, natural disasters. Victims show symptoms of acute stress disorder (ASD) or post

  5. Environmental Chemical Exposures and Autism Spectrum Disorders: A Review of the Epidemiological Evidence

    Kalkbrenner, Amy E.; Schmidt, Rebecca J.; Penlesky, Annie C.

    2016-01-01

    In the past decade, the number of epidemiological publications addressing environmental chemical exposures and autism has grown tremendously. These studies are important because it is now understood that environmental factors play a larger role in causing autism than previously thought and because they address modifiable risk factors that may open up avenues for the primary prevention of the disability associated with autism. In this review, we covered studies of autism and estimates of exposure to tobacco, air pollutants, volatile organic compounds and solvents, metals (from air, occupation, diet, dental amalgams, and thimerosal-containing vaccines), pesticides, and organic endocrine-disrupting compounds such as flame retardants, non-stick chemicals, phthalates, and bisphenol A. We included studies that had individual-level data on autism, exposure measures pertaining to pregnancy or the 1st year of life, valid comparison groups, control for confounders, and adequate sample sizes. Despite the inherent error in the measurement of many of these environmental exposures, which is likely to attenuate observed associations, some environmental exposures showed associations with autism, especially traffic-related air pollutants, some metals, and several pesticides, with suggestive trends for some volatile organic compounds (e.g., methylene chloride, trichloroethylene, and styrene) and phthalates. Whether any of these play a causal role requires further study. Given the limited scope of these publications, other environmental chemicals cannot be ruled out, but have not yet been adequately studied. Future research that addresses these and additional environmental chemicals, including their most common routes of exposures, with accurate exposure measurement pertaining to several developmental windows, is essential to guide efforts for the prevention of the neurodevelopmental damage that manifests in autism symptoms. PMID:25199954

  6. The British Sign Language Versions of the Patient Health Questionnaire, the Generalized Anxiety Disorder 7-Item Scale, and the Work and Social Adjustment Scale

    Rogers, Katherine D.; Young, Alys; Lovell, Karina; Campbell, Malcolm; Scott, Paul R.; Kendal, Sarah

    2013-01-01

    The present study is aimed to translate 3 widely used clinical assessment measures into British Sign Language (BSL), to pilot the BSL versions, and to establish their validity and reliability. These were the Patient Health Questionnaire (PHQ-9), the Generalized Anxiety Disorder 7-item (GAD-7) scale, and the Work and Social Adjustment Scale (WSAS).…

  7. THERAPEUTIC EVALUATION OF YASHTIMADHU GHANA VATI AND TAGARA GHANA VATI ALONG WITH PSYCHOTHERAPY IN THE MANAGEMENT OF MENTAL ADJUSTMENT DISORDER OF YOUNG ADULTS

    Pavankumar Godatwar

    2013-07-01

    Full Text Available Being a health science with holistic approach, Ayurveda looks the mind as integral part of life and health. It advocates the inter-relationship between mind, body and spirit as a whole. It means an imbalance of mental level is equally reflected and re-enforced at physical level and vice versa. When allowed to persist for long time, the psychic and somatic disorders get combined with each other. Ayurveda recommends certain practices to control mind in a view of achieving mental health. So for that purpose present study includes both Drug and Psychotherapy. 112 patients were screened from the survey study (367 and were randomly divided into two groups by Chit method. After completion of trial it was observed that Yashtimadhu & Tagara both are equally effective in a Mental Adjustment disorders though their mode of actions are different.Keywords: Ayurveda, Yashtimadhu, Tagara, mental adjustment disorder, Glycyrrhiza glabra, Valeriana wallichii

  8. Epidemiological study on periodontal diseases and some other dental disorders in dogs

    The prevalence of dental disorders in dogs was studied by applying index systems for human with some modifications. A total of 251 mongrel dogs including 143 stray dogs kept in the Animal Protection Offices in Tokyo and Hokkaido and 108 pet dogs visiting veterinary clinicians in Chiba Prefecture and Hokkaido were used. Periodontitis was prevalent among these dogs regardless of their sources and its incidence was increased with age. The lesion was more severe and more frequent in the premolar and molar regions than in the maxillary and mandibular incisor regions. Missing of teeth was observed at a high and increasing incidence with age. The tooth most commonly lost was the first premolar, followed by the other premolars and molars, where severe periodontitis was frequently found. Calculus was seen on many teeth, and aging agravated its prevalence and severity. Dental caries was observed in stray dogs, but neither to a serious degree nor at a significant level. These findings emphasize the necessity of dental hygiene, proper dental care and continuous periodical survey for dogs

  9. Validity of reaction to severe stress and adjustment disorder diagnoses in the Danish Psychiatric Central Research Registry

    Svensson E; Lash TL; Resick PA; Hansen JG; Gradus JL

    2015-01-01

    Elisabeth Svensson,1 Timothy L Lash,1,2 Patricia A Resick,3 Jens Georg Hansen,1 Jaimie L Gradus4–61Department of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark; 2Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA; 3Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA; 4National Center for PTSD, VA Boston Healthcare System, Boston, MA, USA; 5Department of Psy...

  10. Epidemiological and clinical aspects of bipolar disorders: controversies or a common need to redefine the aims and methodological aspects of surveys

    Angst Jules

    2005-04-01

    Full Text Available Abstract Data from surveys of large samples showed the lifetime prevalence rates of bipolar disorder around 1.5%. A main question is whether the low prevalence rates of bipolar disorders are not an artefact of the over-diagnosis of depression and under-diagnosis of bipolar-II. Analysis of the clinician's logical inferential diagnostic process, confirms that the patient does not represent the sole source of useful information because many patients do not experience hypomania as distress but rather as recovery from depression or as a period during which they felt truly well. Epidemiological data are derived from interviews carried out by lay staff which only reflect the patient's point of view. The clinical monitoring study carried out alongside the ESEMED project found for the diagnosis of mood disorders, a Kappa agreement (versus clinical interview which ranged from 0.23 in Spain to 0.49 in France. If we consider exactly what a Kappa of 0.4 implies for a disorder with an "identified" prevalence rate of 2%, we discover that the prevalence rate may have been under-diagnosed approximately 1.5-fold, so 67% of cases may not have been identified and 50% of the identified cases may be false positives. It is legitimate to surmise that the prevalence reported by recent (extremely costly epidemiological surveys may be doubtful. Which direction should epidemiology take in dealing with the serious matter of bipolar disorders? Recently, some community surveys were carried out in the USA using the Mood Disorder Questionnaire. In the ensuing debate, one side claimed that the instrument was scarcely accurate when used in the general population, gave rise to numerous false positives and that the high prevalence reported was therefore a mere artefact. The other side defended the results reported by the research studies, on the basis that "positive" cases were homogeneous with regard to the high level of subjective distress, low social functioning and employment

  11. Prevalence of mental disorders, psychosocial distress and need for psychosocial support in cancer patients – study protocol of an epidemiological multi-center study

    Mehnert Anja

    2012-07-01

    Full Text Available Abstract Background Empirical studies investigating the prevalence of mental disorders and psychological distress in cancer patients have gained increasing importance during recent years, particularly with the objective to develop and implement psychosocial interventions within the cancer care system. Primary purpose of this epidemiological cross-sectional multi-center study is to detect the 4-week-, 12-month-, and lifetime prevalence rates of comorbid mental disorders and to further assess psychological distress and psychosocial support needs in cancer patients across all major tumor entities within the in- and outpatient oncological health care and rehabilitation settings in Germany. Methods/Design In this multicenter, epidemiological cross-sectional study, cancer patients across all major tumor entities will be enrolled from acute care hospitals, outpatient cancer care facilities, and rehabilitation centers in five major study centers in Germany: Freiburg, Hamburg, Heidelberg, Leipzig and Würzburg. A proportional stratified random sample based on the nationwide incidence of all cancer diagnoses in Germany is used. Patients are consecutively recruited in all centers. On the basis of a depression screener (PHQ-9 50% of the participants that score below the cutoff point of 9 and all patients scoring above are assessed using the Composite International Diagnostic Interview for Oncology (CIDI-O. In addition, all patients complete validated questionnaires measuring emotional distress, information and psychosocial support needs as well as quality of life. Discussion Epidemiological data on the prevalence of mental disorders and distress provide detailed and valid information for the estimation of the demands for the type and extent of psychosocial support interventions. The data will provide information about specific demographic, functional, cancer- and treatment-related risk factors for mental comorbidity and psychosocial distress, specific

  12. Autism and autistic spectrum disorders in the context of new DSM-V classification, and clinical and epidemiological data

    Stanković Miodrag; Lakić Aneta; Ilić Neda

    2012-01-01

    Autism is one of disorders from the autism spectrum, besides Asperger syndrome, atypical autism and pervasive developmental disorder not otherwise specified. They are classified as mental disorders as being manifested by a wide range of cognitive, emotional and neurobehavioural abnormalities. Key categorical characteristics of the disorder are clear impairments of the development of the child’s socialisation, understanding and production of verbal and non-verbal communication and restri...

  13. Prevalence of attention deficit hyperactivity disorder among children and adolescents in Spain: a systematic review and meta-analysis of epidemiological studies

    Catalá-López Ferrán

    2012-10-01

    Full Text Available Abstract Background Attention deficit hyperactivity disorder (ADHD is a commonly diagnosed neuropsychiatric disorder in childhood, but the frequency of the condition is not well established in many countries. The aim of the present study was to quantify the overall prevalence of ADHD among children and adolescents in Spain by means of a systematic review and meta-analysis. Methods PubMed/MEDLINE, IME, IBECS and TESEO were comprehensively searched. Original reports were selected if they provided data on prevalence estimates of ADHD among people under 18 years old in Spain and were cross-sectional, observational epidemiological studies. Information from included studies was systematically extracted and evaluated. Overall pooled-prevalence estimates of ADHD were calculated using random-effects models. Sources of heterogeneity were explored by means sub-groups analyses and univariate meta-regressions. Results Fourteen epidemiological studies (13,026 subjects were selected. The overall pooled-prevalence of ADHD was estimated at 6.8% [95% confidence interval (CI 4.9 – 8.8%] representing 361,580 (95% CI 260,550 – 467,927 children and adolescents in the community. There was significant heterogeneity (P Conclusions Our findings suggest that the prevalence of ADHD among children and adolescents in Spain is consistent with previous studies conducted in other countries and regions. This study represents a first step in estimating the national burden of ADHD that will be essential to building evidence-based programs and services.

  14. Autism and autistic spectrum disorders in the context of new DSM-V classification, and clinical and epidemiological data

    Stanković Miodrag

    2012-01-01

    Full Text Available Autism is one of disorders from the autism spectrum, besides Asperger syndrome, atypical autism and pervasive developmental disorder not otherwise specified. They are classified as mental disorders as being manifested by a wide range of cognitive, emotional and neurobehavioural abnormalities. Key categorical characteristics of the disorder are clear impairments of the development of the child’s socialisation, understanding and production of verbal and non-verbal communication and restricted and repetitive patterns of behaviour. Demarcation boundaries are not clear, neither within the very group of the disorders from the autistic spectrum, nor with respect to the autistic behavioural features in the general population. For this reason, the term spectrum points out the significance of the dimensional assessment of autistic disorders, which will most likely be the basis of the new diagnostic classification of the disorders belonging to the current group of pervasive developmental disorders in the new DSM-V classification. The understanding, as well as the prevalence of the autistic spectrum disorders has changed drastically in the last four decades. From the previous 4 per 10,000 people, today’s prevalence estimates range from 0.6 to around 1%, and the increase of prevalence cannot be explained solely by better recognition on the part of experts and parents or by wider diagnostic criteria. The general conclusion is that the autistic spectrum disorders are no longer rare conditions and that the approach aimed at acknowledging the warning that this is an urgent public health problem is completely justified.

  15. A register based epidemiological description of risk factors and outcomes for major psychiatric disorders, focusing on a comparison between bipolar affective disorder and schizophrenia

    Laursen, Thomas Munk

    2006-01-01

    up against other models than the traditional Kraepelinian dichotomization of the disorders. In conclusion, the results suggest that schizophrenia and bipolar affective disorder patients have a genetic vulnerability or predisposition towards the disorders (possibly at least overlapping), and......This Ph.D. thesis summarizes the results from 3 cohort studies describing risk factors for and mortality of major psychiatric disorders with focus on comparison between schizophrenia and bipolar affective disorder. Furthermore, the results are evaluated in the context of the dichotomization of...... schizophrenia and bipolar affective disorder. The studies were based on four Danish registers: the Psychiatric Central Register, the Danish Civil Registration System, the Cause of Death Register, and the Danish Medical Birth Register. From the registers, large population based cohorts were identified and...

  16. Genetic epidemiology of mental health : twin and family studies of personality disorders, phobias, and symptoms of anxiety and depression

    2009-01-01

    In this thesis we use genetically informative samples of twins and nuclear families to estimate the relative influence of genetic and environmental risk factors for a varied set of mental disorders. In the first two papers, we consider personality disorders (PDs), a class of psychopathology characterised by marked deviations from contemporary expectations of society. To date there have been no large population based twin studies of personality disorders as assessed by structured intervie...

  17. Changes in problematic and disordered eating after gastric bypass, adjustable gastric banding and vertical sleeve gastrectomy: a systematic review of pre-post studies.

    Opozda, M; Chur-Hansen, A; Wittert, G

    2016-08-01

    Despite differences in their mechanisms and outcomes, little is known about whether postsurgical changes in eating behaviours also differ by bariatric procedure. Following a systematic search, 23 studies on changes in binge eating disorder (BED) and related behaviours, bulimia nervosa and related behaviours, night eating syndrome, grazing and emotional eating after Roux-en-Y gastric bypass (RYGB), adjustable gastric banding (AGB) and vertical sleeve gastrectomy (VSG) were reviewed. Significant methodological problems and a dearth of literature regarding many behaviours and VSG were seen. Regarding BED and related behaviours, although later re-increases were noted, short to medium-term reductions after RYGB were common, and reported changes after AGB were inconsistent. Short to medium-term reductions in emotional eating, and from a few studies, short to long-term reductions in bulimic symptoms, were reported after RYGB. Reoccurrences and new occurrences of problem and disordered eating, especially BED and binge episodes, were apparent after RYGB and AGB. Further conclusions and comparisons could not be made because of limited or low-quality evidence. Long-term comparison studies of changes to problematic and disordered eating in RYGB, AGB and VSG patients are needed. It is currently unclear whether any bariatric procedure leads to long-term improvement of any problematic or disordered eating behaviours. PMID:27296934

  18. Psychological Adjustment and Sibling Relationships in Siblings of Children with Autism Spectrum Disorders: Environmental Stressors and the Broad Autism Phenotype

    Petalas, Michael A.; Hastings, Richard P.; Nash, Susie; Hall, Louise M.; Joannidi, Helen; Dowey, Alan

    2012-01-01

    Research with siblings of children with Autism Spectrum Disorders (ASD) suggests that they may be at increased risk for behavioural and emotional problems and relatively poor sibling relationships. This study investigated a diathesis-stress model, whereby the presence of Broad Autism Phenotype features in the typically developing siblings might…

  19. Family Adjustment to Aphasia

    ... Public / Speech, Language and Swallowing / Disorders and Diseases Family Adjustment to Aphasia Richard S. was a senior manager ... It also presents a great challenge to the family. There may be tension among family members and ...

  20. Gender Differences in Borderline Personality Disorder Features in an Epidemiological Sample of Adults Age 55-64: Self Versus Informant Report.

    Busch, Alexander J; Balsis, Steve; Morey, Leslie C; Oltmanns, Thomas F

    2016-06-01

    The literature on the prevalence of borderline personality disorder (BPD) across gender reveals multiple trends. A number of studies indicate that women have a higher prevalence. Others indicate no difference, and a few even reveal that men have a higher prevalence. Yet existing studies are plagued by sampling biases, use mainly self-reported information, and tend to report general prevalence of BPD categorically defined. The current investigation attempted to shed new light on this literature by analyzing BPD features dimensionally in a representative epidemiological sample of adults ages 55-64, using both self- and informant-reported perspectives. Data from the St. Louis Personality and Aging Network study revealed a significant interaction across gender and perspective, F(1, 1360) = 23.46, p < .01. Gender differences were found for self-report only, such that men reported greater BPD severity. Meanwhile, informant report indicated no gender difference. Trends underscore the importance of epidemiological sampling and multiple assessment perspectives when analyzing BPD. PMID:26067157

  1. Interactions between physical and psychosocial risk factors at work increase the risk of back disorders: an epidemiological approach

    Devereux, J. J.; Buckle, P. W.; Vlachonikolis, I. G.

    1999-01-01

    OBJECTIVES: To investigate the possible interactions between physical and psychosocial risk factors at work that may be associated with self reported back disorders. METHODS: 891 of 1514 manual workers, delivery drivers, technicians, customer services computer operators, and general office staff reported risk factors at work and back disorders with a self administered questionnaire (59% return rate). Of the 869 respondents with a valid questionnaire, 638 workers were classified in to on...

  2. La epidemiología y los factores de riesgo de los trastornos alimentarios en la adolescencia: una revisión Epidemiology and risk factors of eating disorder in adolescence: a review

    M. L. Portela de Santana

    2012-04-01

    Full Text Available Introducción: En la actualidad, existe la mayor ocurrencia de enfermedades de origen biopsicosocial, en especial los trastornos alimentarios, que involucran diferentes sistemas del cuerpo y los aspectos inherentes a la persona y sus relaciones sociales. Objetivo: Abordar temas actuales y relevantes acerca de la prevalencia, la incidencia y los factores de riesgo de anorexia y bulimia nerviosa en la adolescencia. Métodos: Búsqueda en las bases de datos MEDLINE, SciELO y LILACS de estudios publicados sobre la epidemiología y los factores de riesgo de trastornos alimentarios en la adolescencia. Resultados: La mayor incidencia de la anorexia y bulimia nerviosa se presenta entre las niñas en la fase media y final de la adolescencia. Entre los factores que aumentan el riesgo para la aparición de los trastornos alimentarios en la adolescencia se encuentran: la genética, los cambios corporales en la pubertad, la vulnerabilidad de los adolescentes a los ideales de delgadez, la presión social por ser delgada, la insatisfacción con la imagen corporal, la dieta restrictiva, la depresión y la baja autoestima. Sin embargo, se sugiere que en las diferentes culturas los trastornos del comportamiento alimentario pueden venir de una serie de condiciones no relacionadas con las conductas compensatorias o con el peso, pero con la forma del cuerpo o parte de lo mismo. Conclusiones: Varios factores determinan la aparición de la anorexia y la bulimia en la adolescencia, sin embargo, no hay consenso en cómo interactúan estos factores en este complejo proceso, lo que indica la necesidad de más investigaciones.Introduction: Currently, there is a higher occurrence of biopsychosocial diseases, especially eating disorders, involving different body systems and aspects related to the individual and their social relations. Objective: Addressing current and relevant issues about the prevalence, incidence and risk factors for anorexia and bulimia nervosa in

  3. Epidemiological survey of mental disorders and knowledge attitude practice upon mental health among people in Bangkok Metropolis.

    Thavichachart, N; Intoh, P; Thavichachart, T; Meksupa, O; Tangwongchai, S; Sughondhabirom, A; Worakul, P

    2001-06-01

    To find the prevalence of 8 mental disorders and study knowledge, attitude, practice (KAP) upon mental health among people in Bangkok Metropolis a cross sectional, descriptive community survey was conducted. Two thousand, nine hundred and forty eight samples aged 15-60 years were selected by a multistage simple random sampling technique. Data collection was made by qualified interviewers who had experience in mental health care and had been trained to use the questionaires. The questionaires had been modified from DSM-IV and CIDI that had been tested for good validity and reliability. The survey methodology was divided into 2 stages, screening and diagnosis. The results showed that the life time prevalence of mental disorders were; schizophrenia (1.3%), mood disorders; manic episode (9.3%), major depressive episode (19.9%), dysthymia (1%), anxiety disorders (10.2%), mental retardation (1.8%), epilepsy (1.3%), suicidal idea (7.1%), drug and substances use disorders (11.2%), and alcohol use disorders (18.4%). Knowledge score was good, attitude was fairly good, practice was still weak in promotion and prevention aspects. As such, this study was used as a pattern to conduct a national survey in 14 provinces all over Thailand and the results are being summarized. The information is similar to the Global Burden of Diseases. We produced a national training program on "Detection and Management of Depression" for Primary Care Physicians that was, a 2 days' workshop. Other national programs promoting prevention and control have also been set up. PMID:11529323

  4. Psychiatric disorders in Norwegian 8- to 10-year-olds: an epidemiological survey of prevalence, risk factors, and service use

    Heiervang, Einar; Stormark, Kjell M; Lundervold, Astri J; Heimann, Mikael; Goodman, Robert; Posserud, Maj-Britt; Ullebø, Anne K; Plessen, Kerstin J; Bjelland, Ingvar; Lie, Stein A; Gillberg, Christopher

    2007-01-01

    %) were assessed with the Development and Well-Being Assessment in the second phase. The weighted prevalence for any DSM-IV psychiatric disorder was 7.0% (95% confidence interval 5.6%-8.5%). Disorders were associated with age, gender, learning difficulties, family type, and poverty. Although 75% of...... population included all 9,430 children attending grades 2 to 4 in Bergen schools during the academic year 2002/2003. The main screening instrument was the Strengths and Difficulties Questionnaire, whereas diagnoses were based on the Development and Well-Being Assessment. Information about child and family...

  5. Disability and quality of life impact of mental disorders in Europe : results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project

    Alonso, J; Angermeyer, M C; Bernert, S; Bruffaerts, R; Brugha, T S; Bryson, H; de Girolamo, G; Graaf, R; Demyttenaere, K; Gasquet, I; Haro, J M; Katz, S J; Kessler, R C; Kovess, V; Lépine, J P; Ormel, J; Polidori, G; Russo, L J; Vilagut, G; Almansa, Josue; Arbabzadeh-Bouchez, S; Autonell, J; Bernal, M; Buist-Bouwman, M A; Codony, M; Domingo-Salvany, A; Ferrer, M; Joo, S S; Martínez-Alonso, M; Matschinger, H; Mazzi, F; Morgan, Z; Morosini, P; Palacín, C; Romera, B; Taub, N; Vollebergh, W A M

    2004-01-01

    Objective: This manuscript examines the impact of mental health state and specific mental and physical disorders on work role disability and quality of life in six European countries. Method: The ESEMeD study was conducted in: Belgium, France, Germany, Italy, the Netherlands and Spain. Individuals a

  6. The Genetics of Obsessive-Compulsive Disorder and Tourette Syndrome: An Epidemiological and Pathway-Based Approach for Gene Discovery

    Grados, Marco A.

    2010-01-01

    Objective: To provide a contemporary perspective on genetic discovery methods applied to obsessive-compulsive disorder (OCD) and Tourette syndrome (TS). Method: A review of research trends in genetics research in OCD and TS is conducted, with emphasis on novel approaches. Results: Genome-wide association studies (GWAS) are now in progress in OCD…

  7. Autism Spectrum Disorders According to "DSM-IV-TR" and Comparison with "DSM-5" Draft Criteria: An Epidemiological Study

    Mattila, Marja-Leena; Kielinen, Marko; Linna, Sirkka-Liisa; Jussila, Katja; Ebeling, Hanna; Bloigu, Risto; Joseph, Robert M.; Moilanen, Irma

    2011-01-01

    Objective: The latest definitions of autism spectrum disorders (ASDs) were specified in "DSM-IV-TR" in 2000. "DSM-5" criteria are planned for 2013. Here, we estimated the prevalence of ASDs and autism according to "DSM-IV-TR," clarified confusion concerning diagnostic criteria, and evaluated "DSM-5" draft criteria for ASD posted by the American…

  8. 孤独症谱系障碍流行病学研究现状%Current study on epidemiology of autism spectrum disorder

    李洪华; 杜琳; 单玲; 冯俊燕; 贾飞勇

    2014-01-01

    儿童孤独症是一类起病于3岁以前的神经系统发育障碍,属于广泛性发育障碍的一个亚型。精神障碍诊断与统计手册第五版(DSM-Ⅴ)已将其归类为孤独症谱系障碍(ASD)。1980年以前,孤独症被认为是一种罕见性疾病,而近些年有关孤独症及ASD的流行病学研究表明,其发病率日趋上升,2014年美国疾病控制与预防中心对11个州8岁儿童的监测数据发现,ASD患病率高达14.7/1000,即相当于68例儿童中即有1例为ASD患儿,本文综述了目前ASD流行病学研究现状,并分析患儿性别、种族、智力、地域间的差异,为ASD的早期发现与早期干预提供理论依据。%Autism is a neurodevelopmental disorder with onset before the age of 3 years old, and is a subtype of pervasive developmental disorder. It has been classified as autism spectrum disorder in DSM-Ⅴ. Before 1980, autism was considered as a rare disease, in recent years, the epidemiological studies show that the incidence of autism tends to rise. In 2014, from the site of the Centers for Disease Control and Prevention of America, the overall prevalence of ASD among the ADDM sites was 14.7 per 1 000 children, which is equivalent to 68 cases of children that have one case for children with autism, we reviewed the study of epidemiology of ASD and analyzed the differences of gender, race, intelligence and regions of them, so as to provide a theoretical basis for its early detection and intervention.

  9. Prevalence of psychological distress and mental disorders, and use of mental health services in the epidemiological catchment area of Montreal South-West

    Caron Jean

    2012-10-01

    Full Text Available Abstract Background This report presents the initial results of the first Epidemiological Catchment Area Study in mental health in Canada. Five neighbourhoods in the South-West sector of Montreal, with a population of 258,000, were under study. The objectives of the research program were: 1 to assess the prevalence and incidence of psychological distress, mental disorders, substance abuse, parasuicide, risky behaviour and quality of life; 2 to examine the links and interactions between individual determinants, neighbourhood ecology and mental health in each neighbourhood; 3 to identify the conditions facilitating the integration of individuals with mental health problems; 4 to analyse the impact of the social, economic and physical aspects of the neighbourhoods using a geographic information system. 5 to verify the adequacy of mental health services. Method A longitudinal study in the form of a community survey was used, complemented by focused qualitative sub-studies. The longitudinal study included a randomly selected sample of 2,433 individuals between the ages of 15 and 65 in the first wave of data collection, and three other waves are projected. An overview of the methods is presented. Results The prevalence of psychological distress, mental disorders and use of mental health services and their correlates are described for the first wave of data collection. Conclusion Several vulnerable groups and risk factors related to socio-demographic variables have been identified such as: gender, age, marital status, income, immigration and language. These results can be used to improve treatment services, prevention of mental disorders, and mental health promotion.

  10. Family function, Parenting Style and Broader Autism Phenotype as Predicting Factors of Psychological Adjustment in Typically Developing Siblings of Children with Autism Spectrum Disorders.

    Mohammadreza Mohammadi

    2014-06-01

    Full Text Available Siblings of children with autism are at a greater risk of experiencing behavioral and social problems. Previous researches had focused on environmental variables such as family history of autism spectrum disorders (ASDs, behavior problems in the child with an ASD, parental mental health problems, stressful life events and "broader autism phenotype" (BAP, while variables like parenting style and family function that are shown to influence children's behavioral and psychosocial adjustment are overlooked. The aim of the present study was to reveal how parenting style and family function as well as BAP effect psychological adjustment of siblings of children with autism.The Participants included 65 parents who had one child with an Autism Spectrum Disorder and one typically developing child. Of the children with ASDs, 40 were boys and 25 were girls; and they were diagnosed with ASDs by a psychiatrist based on DSM-IV-TR criteria and Autism Diagnostic Interview-Revised (ADI-R. The Persian versions of the six scales were used to collect data from the families. Pearson's correlation test and regression analysis were used to determine which variables were related to the psychological adjustment of sibling of children with ASDs and which variables predicted it better.Significant relationships were found between Strengths and Difficulties Questionnaire (SDQ total difficulties, prosocial behaviors and ASDs symptoms severity, parenting styles and some aspects of family function. In addition, siblings who had more BAP characteristics had more behavior problems and less prosocial behavior. Behavioral problems increased and prosocial behavior decreased with permissive parenting style. Besides, both of authoritarian and authoritative parenting styles led to a decrease in behavioral problems and an increase in prosocial behaviors. Our findings revealed that some aspects of family function (affective responsiveness, roles, problem solving and behavior control were

  11. ADJUSTMENT FACTORS AND ADJUSTMENT STRUCTURE

    Tao Benzao

    2003-01-01

    In this paper, adjustment factors J and R put forward by professor Zhou Jiangwen are introduced and the nature of the adjustment factors and their role in evaluating adjustment structure is discussed and proved.

  12. Prevalence and Correlates of DSM-IV Mental Disorders in South Korean Adults: The Korean Epidemiologic Catchment Area Study 2011

    Cho, Maeng Je; Seong, Su Jeong; Park, Jee Eun; Chung, In-Won; Lee, Young Moon; Bae, Ahn; Ahn, Joon Ho; Lee, Dong-Woo; Bae, Jae Nam; Cho, Seong-Jin; Park, Jong-Ik; Son, Jungwoo; Chang, Sung Man; Hahm, Bong-Jin; Lee, Jun-Young

    2015-01-01

    Objective The aim of this study was to estimate the prevalence and correlates of mental disorders in Korean adults. Methods Door to door household surveys were conducted with community residents aged 18-74 years from July 19, 2011, to November 16, 2011 (n=6,022, response rate 78.7%). The sample was drawn from 12 catchment areas using a multistage cluster method. Each subject was assessed using the Korean version of the World Health Organization Composite International Diagnostic Interview (CI...

  13. Epidemiologia dos distúrbios respiratórios do sono Epidemiology of sleep-disordered breathing

    Carlos Alberto de Assis Viegas

    2010-06-01

    Full Text Available Os principais distúrbios respiratórios do sono, ronco e SAOS, são muito prevalentes na população geral, embora se acredite que a maioria dos casos continue não diagnosticada. Devemos estar atentos para os principais fatores de risco que favorecem o aparecimento desses distúrbios, como gênero masculino, obesidade, envelhecimento e características crânio-faciais. Da mesma forma, a presença de hipertensão arterial sistêmica, enfermidades cardiovasculares e metabólicas deve nos alertar para a possibilidade da concomitância de SAOS.The principal types of sleep-disordered breathing-snoring and obstructive sleep apnea syndrome-are highly prevalent in the general population, although it is believed that the majority of cases continue to go undiagnosed. We should be aware of the principal risk factors that favor the onset of these disorders, such as male gender, obesity, aging and craniofacial features. Similarly, systemic arterial hypertension, cardiovascular diseases and metabolic disorders should alert us to the possibility of obstructive sleep apnea syndrome.

  14. Cultura, genes y epidemiología evolutiva en los trastornos del comportamiento alimentario: una polémica interesante Culture, Genes and Evolutive Epidemiology in the Eating Disorders: An Interesting Debate

    Maritza Rodríguez G

    2005-12-01

    Full Text Available Introducción y objetivos: Este artículo explora los trastornos del comportamiento alimentario (TCA como síndromes ligados a la cultura y discute tanto la influencia del entorno como la implicación de los genes en su etiología. Se revisa la paradoja de la inanición autoimpuesta en medio de la abundancia, la presión sociocultural sobre el ideal de delgadez y el papel de una cultura que rinde tributo a la imagen uniforme. Finalmente, se discute la función de los genes en su etiopatogenia. Método: Revisión de la literatura médica sobre el tema y planteamiento de algunas hipótesis. Resultados: Se presentan cuatro perspectivas: una revisión del comportamiento epidemiológico de los TCA en diferentes contextos históricos y geográficos; un resumen cualitativo de la existencia de comportamientos anoréxicos y bulímicos a lo largo de la historia, antes de su reconocimiento formal como entidades clínicas; algunas hipótesis derivadas de la epidemiología evolutiva y de la psiquiatría darwiniana para explicar su aparición, y algunas consideraciones sobre el estado del conocimiento actual acerca del papel que parecen desempeñar los genes en su expresión y mantenimiento. Conclusiones: Se plantean conclusiones sobre la influencia del entorno, la expresión de los genes, las hipótesis darwinianas y las características de personalidad en los TCA.Introduction and objectives: This paper explores Eating Disorders (ED as a culture-bound syndrome and discusses the environmental and genetic roles in their etiology. The paradox of self-starvation amidst wealth is revised, as well as, socio-cultural pressure of an ideal thin body shape, and the role of a society that exerts pressure for a uniformed body appearance. Finally the role of genes on the pathogenesis is discussed. Methods: The author review the literature about the topic and make some hypothesis about it. Results: Four lines of evidence will be presented to answer these questions.1 an

  15. WHO - IPHECA: Epidemiological aspects

    In May 1991 the World Health Assembly endorsed the establishment of the International Programme on the Health Effects of the Chernobyl Accident (IPHECA) under the auspices of WHO. Five pilot projects have been carried out within IPHECA in the study territories of Belarus, Russian Federation and Ukraine in a period from 1991 to 1994. This pilot projects dealt with the detection and treatment of leukaemia and related diseases (Haematology Project), thyroid disorders (Thyroid project), brain damage during exposure 'in-utero' (Brain Damage 'in-Utero' project) and with the development of the Chernobyl registries (Epidemiological Registry Project). A fifth pilot project on oral health was performed only in Belarus. Epidemiological investigations have been an important component of all IPHECA pilot projects. Within 'Epidemiological Registry' Project such investigations have been the principal activity. But with respect to other IPHECA projects it was carried out in addition to main objectives relating to medical monitoring, early diagnosis and treatment of specific diseases included in project protocols. To support the epidemiological investigations within IPHECA, WHO supplied 41 computers in Belarus, Russian Federation and Ukraine and provided training for specialists from these countries in internationally recognized centres. The training programmes and host countries were as follows: standardization of epidemiological investigations (United Kingdom), radiation epidemiology (Russia), development of software (United Kingdom), principles of epidemiological investigations (The Czech Republic), cohort investigations (Japan)

  16. Psychiatric disorders in Norwegian 8- to 10-year-olds: an epidemiological survey of prevalence, risk factors, and service use

    Heiervang, Einar; Stormark, Kjell M; Lundervold, Astri J;

    2007-01-01

    OBJECTIVE: The Bergen Child Study is a longitudinal study of child mental health from the city of Bergen, Norway. We present methods and results from the first wave of the study, focusing on prevalence of disorders, associations with risk factors, and the use of services. METHOD: The target...... population included all 9,430 children attending grades 2 to 4 in Bergen schools during the academic year 2002/2003. The main screening instrument was the Strengths and Difficulties Questionnaire, whereas diagnoses were based on the Development and Well-Being Assessment. Information about child and family...

  17. Alcohol use disorders increase the risk of completed suicide - Irrespective of other psychiatric disorders. A longitudinal cohort study

    Flensborg-Madsen, Trine; Knop, Joachim; Mortensen, Erik Lykke;

    2009-01-01

    : Completed suicide, AUD, Psychotic disorders, Anxiety disorders, Mood disorders, Personality disorders, Drug abuse, and Other psychiatric disorders. Individuals registered with AUD were at significantly increased risk of committing suicide, with a crude hazard ratio (HR) of 7.98 [Confidence interval (CI): 5......Knowledge of the epidemiology of suicide is a necessary prerequisite for developing prevention programs. The aim of this study was to analyze the risk of completed suicide among individuals with alcohol use disorders (AUD), and to assess the role of other psychiatric disorders in this association.......27-12.07] compared to individuals without AUD. Adjusting for all psychiatric disorders the risk fell to 3.23 (CI: 1.96-5.33). In the stratified sub-sample of individuals without psychiatric disorders, the risk of completed suicide was 9.69 (CI: 4.88-19.25) among individuals with AUD. The results indicate that...

  18. Exposure to environmental and lifestyle factors and attention-deficit / hyperactivity disorder in children - a review of epidemiological studies.

    Polańska, Kinga; Jurewicz, Joanna; Hanke, Wojciech

    2012-09-01

    Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children. Although the mechanisms that lead to the development of ADHD remain unclear, genetic and environmental factors have been implicated. These include heavy metals and chemical exposures, nutritional and lifestyle/psychosocial factors. The aim of this review was to investigate the association between ADHD or ADHD-related symptoms and widespread environmental factors such as phthalates, bisphenol A (BPA), tobacco smoke, polycyclic aromatic hydrocarbons (PAHs), polyfluoroalkyl chemicals (PFCs) and alcohol. Medline, PubMed and Ebsco search was performed to identify the studies which analyze the association of prenatal and postnatal child exposure to environmental toxicants and lifestyle factors and ADHD or ADHD-related symptoms. The review is restricted to human studies published since 2000 in English in peer reviewed journals. Despite much research has been done on the association between environmental risk factors and ADHD or ADHD symptoms, results are not consistent. Most studies in this field, focused on exposure to tobacco smoke, found an association between that exposure and ADHD and ADHD symptoms. On the other hand, the impact of phthalates, BPA, PFCs, PAHs and alcohol is less frequently investigated and does not allow a firm conclusion regarding the association with the outcomes of interest. PMID:23086631

  19. Epidemiology of Injury-Related Emergency Department Visits in the US Among Youth with Autism Spectrum Disorder.

    Kalb, Luther G; Vasa, Roma A; Ballard, Elizabeth D; Woods, Steven; Goldstein, Mitchell; Wilcox, Holly C

    2016-08-01

    Several reports suggest children with autism spectrum disorder (ASD) are more likely to be seen for injury-related ED visits; however, no nationally representative study has examined this question. Using data from the 2008 Nationwide Emergency Department Sample, over a quarter of all visits among those with ASD were related to injury. In the multivariate analyses, the odds of an injury-related visit was 54 % greater among those with ASD compared to youth with intellectual disability (ID), but 48 % less compared to youth without ID or ASD. Compared to all other pediatric injury-visits in the US, visits among children with ASD were more likely to be due to self-inflicted injury and poisoning and were more likely to result in hospitalization (all p < 0.001). PMID:27241347

  20. Relation between post-Chernobyl low level thyroid irradiation, stable iodine deficiency and thyroid disorders in Lithuania (epidemiological study: 1992-1996)

    The volatile radioiodine was detected in Lithuania in the very first day after the Chernobyl accident. Aim of the study was to perform the epidemiological investigation of thyroid disorders among Lithuanian inhabitants and to compare the data with thyroid radioiodine doses and stable iodine deficiency (urinary iodine excreation) results. Thyroid equivalent doses were estimated using the modified ICRP three-compartment cyclic model. These calculations applied Monte Carlo methods and consideration of regional iodine deficiency. The adult thyroid doses range up to about 50 mSv and the infant's and children's doses amounted to 200 mSv. High prevalence of thyroid abnormalities (up to 48%) are attributable to deleterious effect of ionising radiation as well as stable iodine deficiency for geological and socio-economical reasons. These data may be useful for estimating health effects that could develop in the future among Lithuanian inhabitants as a result of stable iodine deficiency and radioiodine exposure following the Chernobyl accident, especially amongst those who were infants at the time of accident. (author)

  1. Self-help interventions for adjustment disorder problems: a randomized waiting-list controlled study in a sample of burglary victims.

    Bachem, Rahel; Maercker, Andreas

    2016-09-01

    Adjustment disorders (AjD) are among the most frequent mental disorders yet often remain untreated. The high prevalence, comparatively mild symptom impairment, and transient nature make AjD a promising target for low-threshold self-help interventions. Bibliotherapy represents a potential treatment for AjD problems. This study investigates the effectiveness of a cognitive behavioral self-help manual specifically directed at alleviating AjD symptoms in a homogenous sample of burglary victims. Participants with clinical or subclinical AjD symptoms following experience of burglary were randomized to an intervention group (n = 30) or waiting-list control group (n = 24). The new explicit stress response syndrome model for diagnosing AjD was applied. Participants received no therapist support and assessments took place at baseline, after the one-month intervention, and at three-month follow-up. Based on completer analyses, group by time interactions indicated that the intervention group showed more improvement in AjD symptoms of preoccupation and in post-traumatic stress symptoms. Post-intervention between-group effect sizes ranged from Cohen's d = .17 to .67 and the proportion of participants showing reliable change was consistently higher in the intervention group than in the control group. Engagement with the self-help manual was high: 87% of participants had worked through at least half the manual. This is the first published RCT of a bibliotherapeutic self-help intervention for AjD problems. The findings provide evidence that a low-threshold self-help intervention without therapist contact is a feasible and effective treatment for symptoms of AjD. PMID:27299909

  2. The epidemiology of pharmacologically treated attention deficit hyperactivity disorder (ADHD) in children, adolescents and adults in UK primary care

    McCarthy, Suzanne

    2012-06-19

    AbstractBackgroundAttention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder characterised by the symptoms of inattention, impulsivity and hyperactivity. ADHD was once perceived as a condition of childhood only; however increasing evidence has highlighted the existence of ADHD in older adolescents and adults. Estimates for the prevalence of ADHD in adults range from 2.5–4%. Few data exist on the prescribing trends of the stimulants methylphenidate and dexamfetamine, and the non-stimulant atomoxetine in the UK. The aim of this study was to investigate the annual prevalence and incidence of pharmacologically treated ADHD in children, adolescents and adults in UK primary care.MethodsThe Health Improvement Network (THIN) database was used to identify all patients aged over 6 years with a diagnosis of ADHD\\/hyperkinetic disorder and a prescription for methylphenidate, dexamfetamine or atomoxetine from 2003–2008. Annual prevalence and incidence of pharmacologically treated ADHD were calculated by age category and sex.ResultsThe source population comprised 3,529,615 patients (48.9% male). A total of 118,929 prescriptions were recorded for the 4,530 patients in the pharmacologically treated ADHD cohort during the 6-year study. Prevalence (per 1000 persons in the mid-year THIN population) increased within each age category from 2003 to 2008 [6–12 years: from 4.8 (95% CI: 4.5–5.1) to 9.2 (95% CI: 8.8–9.6); 13–17 years: from 3.6 (95% CI: 3.3–3.9) to 7.4 (95% CI: 7.0–7.8); 18–24 years: from 0.3 (95% CI: 0.2–0.3) to 1.1 (95% CI: 1.0–1.3); 25–45 years: from 0.02 (95% CI: 0.01–0.03) to 0.08 (95% CI: 0.06–0.10); >45 years: from 0.01 (95% CI: 0.00–0.01) to 0.02 (95% CI: 0.01–0.03). Whilst male patients aged 6-12 years had the highest prevalence; the relative increase in prescribing was higher amongst female patients of the same age - the increase in prevalence in females aged 6–12 years was 2.1 fold

  3. The epidemiology of pharmacologically treated attention deficit hyperactivity disorder (ADHD in children, adolescents and adults in UK primary care

    McCarthy Suzanne

    2012-06-01

    Full Text Available Abstract Background Attention Deficit Hyperactivity Disorder (ADHD is a common neurodevelopmental disorder characterised by the symptoms of inattention, impulsivity and hyperactivity. ADHD was once perceived as a condition of childhood only; however increasing evidence has highlighted the existence of ADHD in older adolescents and adults. Estimates for the prevalence of ADHD in adults range from 2.5–4%. Few data exist on the prescribing trends of the stimulants methylphenidate and dexamfetamine, and the non-stimulant atomoxetine in the UK. The aim of this study was to investigate the annual prevalence and incidence of pharmacologically treated ADHD in children, adolescents and adults in UK primary care. Methods The Health Improvement Network (THIN database was used to identify all patients aged over 6 years with a diagnosis of ADHD/hyperkinetic disorder and a prescription for methylphenidate, dexamfetamine or atomoxetine from 2003–2008. Annual prevalence and incidence of pharmacologically treated ADHD were calculated by age category and sex. Results The source population comprised 3,529,615 patients (48.9% male. A total of 118,929 prescriptions were recorded for the 4,530 patients in the pharmacologically treated ADHD cohort during the 6-year study. Prevalence (per 1000 persons in the mid-year THIN population increased within each age category from 2003 to 2008 [6–12 years: from 4.8 (95% CI: 4.5–5.1 to 9.2 (95% CI: 8.8–9.6; 13–17 years: from 3.6 (95% CI: 3.3–3.9 to 7.4 (95% CI: 7.0–7.8; 18–24 years: from 0.3 (95% CI: 0.2–0.3 to 1.1 (95% CI: 1.0–1.3; 25–45 years: from 0.02 (95% CI: 0.01–0.03 to 0.08 (95% CI: 0.06–0.10; >45 years: from 0.01 (95% CI: 0.00–0.01 to 0.02 (95% CI: 0.01–0.03. Whilst male patients aged 6-12 years had the highest prevalence; the relative increase in prescribing was higher amongst female patients of the same age - the increase in prevalence in females aged 6–12 years was 2

  4. Gender, school and academic year differences among Spanish university students at high-risk for developing an eating disorder: An epidemiologic study

    Carrobles Jose A

    2008-03-01

    Full Text Available Abstract Background The aim of this study was to assess the magnitude of the university population at high-risk of developing an eating disorder and the prevalence of unhealthy eating attitudes and behaviours amongst groups at risk; gender, school or academic year differences were also explored. Methods A cross-sectional study based on self-report was used to screen university students at high-risk for an eating disorder. The sample size was of 2551 university students enrolled in 13 schools between the ages of 18 and 26 years. The instruments included: a social-demographic questionnaire, the Eating Disorders Inventory (EDI, the Body Shape Questionnaire (BSQ, the Symptom Check List 90-R (SCL-90-R, and the Self-Esteem Scale (RSE. The sample design is a non-proportional stratified sample by academic year and school. The prevalence rate was estimated controlling academic year and school. Logistic regression analysis was used to investigate adjusted associations between gender, school and academic year. Results Female students presented unhealthy weight-control behaviours as dieting, laxatives use or self-induced vomiting to lose weight than males. A total of 6% of the females had a BMI of 17.5 or less or 2.5% had amenorrhea for 3 or more months. In contrast, a higher proportion of males (11.6% reported binge eating behaviour. The prevalence rate of students at high-risk for an eating disorder was 14.9% (11.6–18 for males and 20.8% (18.7–22.8 for females, according to an overall cut-off point on the EDI questionnaire. Prevalence rates presented statistically significant differences by gender (p Conclusion The prevalence of eating disorder risk in university students is high and is associated with unhealthy weight-control practices, similar results have been found in previous studies using cut-off points in questionnaires. These results may be taken into account to encourage early detection and a greater awareness for seeking treatment in order

  5. Clinical association between teeth malocclusions, wrong posture and ocular convergence disorders: an epidemiological investigation on primary school children

    Silvestrini-Biavati Armando

    2013-01-01

    Full Text Available Abstract Background As the various systems in the body are inter-connected to form a single structural unit, a pathological condition in one area can also affect other areas. There are many known correlations between the visual and motor system. The importance of visual function, particularly the paracentral peripheral field of view, in motor coordination, ambulation and the maintenance of balance has been amply demonstrated. In line with current medical principles, which are moving towards a more holistic view of the human body, this study aims to investigate, in an interdisciplinary manner, the incidence of dental malocclusions together with posture and eye convergence disorders. Methods Six hundred and five children attending at the 3rd, 4th and 5th years of seven Genoa primary schools were examined. Each child underwent the following examinations: (i dental/occlusal; (ii orthoptic; and (iii postural. Occlusal data concerned the presence of cross-bite, midline deviation with a mandibular shift, bad habits and deep or open bite. Postural assessment involved frontal and lateral inspection, investigation during trunk flexion and ambulation, and note of any asymmetry in the lower limbs. The recorded orthoptic data included those pertaining to ocular dominance, a cover test, convergence and the Brock string test. Results A prevalence of cases with an unphysiological gait was found in patients with overjet (14.70% or overbite (14.87%, while the percentage of patients with normal occlusion that showed an unphysiological gait was 13.08%. Also, about 93.8%–94.2% of children showed normal legs without dysmetry, with no difference in respect to the type of occlusion. Subjects with an open bite or deep bite showed a slightly different distribution of right or left dominant eyes. Conclusion About 13% of children showed a pathological gait and, among them, vertical anomalies of occlusion (deep bite or open bite were prevalent with respect to the other

  6. Convexity Adjustments

    M. Gaspar, Raquel; Murgoci, Agatha

    2010-01-01

    A convexity adjustment (or convexity correction) in fixed income markets arises when one uses prices of standard (plain vanilla) products plus an adjustment to price nonstandard products. We explain the basic and appealing idea behind the use of convexity adjustments and focus on the situations o...

  7. Twelve-month prevalence of psychiatric disorders and treatment-seeking among Asian Americans/Pacific Islanders in the United States: Results from the National Epidemiological Survey on Alcohol and Related Conditions

    Xu, Yang; Okuda, Mayumi; Hser, Yih-Ing; Hasin, Deborah; Liu, Shang-Min; Grant, Bridget F.; Blanco, Carlos

    2011-01-01

    To compare the 12-month prevalence of psychiatric disorders in Asian Americans/Pacific Islanders in contrast to non–Hispanic whites; and further compare persistence and treatment-seeking rates for psychiatric disorders among Asian American/Pacific Islanders and non-Hispanic whites, analyses from the 2001–2002 National Epidemiologic Survey on Alcohol and Related Conditions, Wave 1 (n =43,093) were conducted for the subsample of 1,332 Asian Americans/Pacific Islanders (596 men and 736 women) an...

  8. Detecting disease-associated genes with confounding variable adjustment and the impact on genomic meta-analysis: With application to major depressive disorder

    Wang Xingbin

    2012-03-01

    Full Text Available Abstract Background Detecting candidate markers in transcriptomic studies often encounters difficulties in complex diseases, particularly when overall signals are weak and sample size is small. Covariates including demographic, clinical and technical variables are often confounded with the underlying disease effects, which further hampers accurate biomarker detection. Our motivating example came from an analysis of five microarray studies in major depressive disorder (MDD, a heterogeneous psychiatric illness with mostly uncharacterized genetic mechanisms. Results We applied a random intercept model to account for confounding variables and case-control paired design. A variable selection scheme was developed to determine the effective confounders in each gene. Meta-analysis methods were used to integrate information from five studies and post hoc analyses enhanced biological interpretations. Simulations and application results showed that the adjustment for confounding variables and meta-analysis improved detection of biomarkers and associated pathways. Conclusions The proposed framework simultaneously considers correction for confounding variables, selection of effective confounders, random effects from paired design and integration by meta-analysis. The approach improved disease-related biomarker and pathway detection, which greatly enhanced understanding of MDD neurobiology. The statistical framework can be applied to similar experimental design encountered in other complex and heterogeneous diseases.

  9. Quality of life and risk of psychiatric disorders among regular users of alcohol, nicotine, and cannabis: An analysis of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC).

    Cougle, Jesse R; Hakes, Jahn K; Macatee, Richard J; Chavarria, Jesus; Zvolensky, Michael J

    2015-01-01

    Research is limited on the effects of regular substance use on mental health-related outcomes. We used a large nationally representative survey to examine current and future quality of life and risk of psychiatric disorders among past-year regular (weekly) users of alcohol, nicotine, and cannabis. Data on psychiatric disorders and quality of life from two waves (Wave 1 N = 43,093, Wave 2 N = 34,653) of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC) were used to test study aims. In cross-sectional analyses, regular nicotine and cannabis use were associated with higher rates of psychiatric disorder, though regular alcohol use was associated with lower rates of disorders. Prospective analyses found that regular nicotine use predicted onset of anxiety, depressive, and bipolar disorders. Regular alcohol use predicted lower risk of these disorders. Regular cannabis use uniquely predicted the development of bipolar disorder, panic disorder with agoraphobia, and social phobia. Lastly, regular alcohol use predicted improvements in physical and mental health-related quality of life, whereas nicotine predicted deterioration in these outcomes. Regular cannabis use predicted declines in mental, but not physical health. These data add to the literature on the relations between substance use and mental and physical health and suggest increased risk of mental health problems among regular nicotine and cannabis users and better mental and physical health among regular alcohol users. Examination of mechanisms underlying these relationships is needed. PMID:26022838

  10. Epidemiological Study of Respiratory Disorders Induced by Occupational Inhalation of Talc Powder in Rubber Factory Workers in Shiraz

    M Neghab

    2006-04-01

    exposed workers showed evidence of chronic inflammatory process. Conclusion: These results which are in full agreement with the preliminary observations support the notion that occupational exposure to talc is associated with both acute and chronic respiratory disorders and induces bronchitis and interstitial lung disease.

  11. Asking for work adjustments or initiating behavioural changes - what makes a 'problematic co-worker' score Brownie points? An experimental study on the reactions towards colleagues with a personality disorder.

    Muschalla, Beate; Fay, Doris; Seemann, Anne

    2016-10-01

    People with mental disorders, especially personality disorders, often face low acceptance at work. This is particularly problematic when returning to work after sick leave, because it impedes reintegration into the former workplace. This study explores colleagues' reactions towards a problematic worker dependent on the returning person's reintegration strategy: The returning person undertaking changes in their behaviour is compared with the person requesting adjustments of the workplace. In an experimental study, 188 employed persons read one of four vignettes that described a return-to-work-situation of a problematic co-worker. Across all vignettes, the co-worker was depicted as having previously caused problems in the work team. In the first vignette, the co-worker did not change anything (control condition) when she returned to work; in the second, she asked for workplace adjustments; in the third vignette she initiated efforts to change her own behaviour; and the fourth vignette combined both workplace adjustments and behavioural change. Study participants were asked for their reactions towards the problematic co-worker. Vignettes that included a behavioural change evoked more positive reactions towards the co-worker than vignettes without any behavioural change. Asking for workplace adjustments alone did not yield more positive reactions compared to not initiating any change. When preparing employees with interactional problems for their return to work, it is not effective to only instruct them on their statutory entitlement for workplace adjustments. Instead, it is advisable to encourage them to proactively strive for behaviour changes. PMID:26567587

  12. Melatonin adjusts the expression pattern of clock genes in the suprachiasmatic nucleus and induces antidepressant-like effect in a mouse model of seasonal affective disorder.

    Nagy, Andras David; Iwamoto, Ayaka; Kawai, Misato; Goda, Ryosei; Matsuo, Haruka; Otsuka, Tsuyoshi; Nagasawa, Mao; Furuse, Mitsuhiro; Yasuo, Shinobu

    2015-05-01

    Recently, we have shown that C57BL/6J mice exhibit depression-like behavior under short photoperiod and suggested them as an animal model for investigating seasonal affective disorder (SAD). In this study, we tested if manipulations of the circadian clock with melatonin treatment could effectively modify depression-like and anxiety-like behaviors and brain serotonergic system in C57BL/6J mice. Under short photoperiods (8-h light/16-h dark), daily melatonin treatments 2 h before light offset have significantly altered the 24-h patterns of mRNA expression of circadian clock genes (per1, per2, bmal1 and clock) within the suprachiasmatic nuclei (SCN) mostly by increasing amplitude in their expressional rhythms without inducing robust phase shifts in them. Melatonin treatments altered the expression of genes of serotonergic neurotransmission in the dorsal raphe (tph2, sert, vmat2 and 5ht1a) and serotonin contents in the amygdala. Importantly, melatonin treatment reduced the immobility in forced swim test, a depression-like behavior. As a key mechanism of melatonin-induced antidepressant-like effect, the previously proposed phase-advance hypothesis of the circadian clock could not be confirmed under conditions of our experiment. However, our findings of modest adjustments in both the amplitude and phase of the transcriptional oscillators in the SCN as a result of melatonin treatments may be sufficient to associate with the effects seen in the brain serotonergic system and with the improvement in depression-like behavior. Our study confirmed a predictive validity of C57BL/6J mice as a useful model for the molecular analysis of links between the clock and brain serotonergic system, which could greatly accelerate our understanding of the pathogenesis of SAD, as well as the search for new treatments. PMID:25515595

  13. Environmental epidemiology

    Kopfler, F.; Craun, G.

    1986-01-01

    Topics covered in this book include the following: Use of biological monitoring to assess exposure data; environmental epidemiologic considerations for assessing exposure and associating exposure with morbidity/mortality; health and exposure data bases; and assessment of exposure to environmental contaminants for epidemiologic studies (1) Air Exposure Indoor and Outdoor (2) Water and Occupational Exposures.

  14. Endodontic Epidemiology

    Shahravan, Arash; Haghdoost, Ali Akbar

    2014-01-01

    Epidemiology is the study of disease distribution and factors determining or affecting it. Likewise, endodontic epidemiology can be defined as the science of studying the distribution pattern and determinants of pulp and periapical diseases; specially apical periodontitis. Although different study designs have been used in endodontics, researchers must pay more attention to study designs with higher level of evidence such as randomized clinical trials.

  15. Comorbidity Structure of Psychological Disorders in the Online e-PASS Data as Predictors of Psychosocial Adjustment Measures: Psychological Distress, Adequate Social Support, Self-Confidence, Quality of Life, and Suicidal Ideation

    AL-Asadi, Ali M; Klein, Britt; Meyer, Denny

    2014-01-01

    Background A relative newcomer to the field of psychology, e-mental health has been gaining momentum and has been given considerable research attention. Although several aspects of e-mental health have been studied, 1 aspect has yet to receive attention: the structure of comorbidity of psychological disorders and their relationships with measures of psychosocial adjustment including suicidal ideation in online samples. Objective This exploratory study attempted to identify the structure of co...

  16. Personality disorders

    L.M.C. van den Bosch; R. Verheul

    2012-01-01

    Subject of this chapter is the often found combination of personality disorders and ­substance abuse disorders. The serious nature of this comorbidity is shown through the discussion of prevalence and epidemiological data. Literature shows that the comorbidity, hampering the diagnostic process, is s

  17. [Schizoaffective disorder: An arguable diagnostic entity].

    Garyfallos, G D

    2008-07-01

    Seventy-five years ago, J. Kasanin introduced the term "schizoaffective disorder" to refer to a disorder with symptoms of both schizophrenia and affective disorders. Since then, schizoaffective disorder has raised a considerable amount of discussion about its definition and position as a variant of schizophrenia, a variant of mood disorder or as an entity in between. This ambiguity is reflected on the definition of diagnostic criteria of the disorder in the taxonomic systems, which are practically too complex. Furthermore, there are essential differences between DSM-IV and ICD-10 regarding schizoaffective definition. Finally, the disorder has a very low inter-rater reliability and a very low longitudinal diagnostic stability. All the above have even led to proposals of elimination of schizoaffective disorder as a separate diagnostic entity. The prevalence of the disorder varies between 0.3% and 0.8%. Schizoaf fective disorder is more common in women than in men, a dif ference that is mostly attributed to increased incidence among women of the depressive type. The bipolar type of the disorder is more often found in young adults, whereas the depressive type is commoner in older adults. With regards to other variables such as educational level, marital status, prognosis, occupational level and social adjustment, schizoaffective disorder has more favourable characteristics than schizophrenia and less favourable than mood disorders. Age at onset is earlier than mood disorders and later than schizophrenia. The above epidemiologic and clinical data, as well as data from family, twin, genetic and neuroimaging studies, indicate that schizoaffective disorder can be best viewed as a mid-point on a continuum between schizophrenia and mood disorders and represents the most prominent paradigm challenging the so-called "Kraepelinian dichotomy" of major psychiatric disorders. Though schizoaffective disorder is a nosological nuisance, it is also a clinical reality and it is not

  18. Epidemiological criminology

    Ignjatović Đorđe

    2015-01-01

    Paper deals with one of so-called „new criminologies“ - specific amalgam composed by criminological and epidemiological experiences. First of all, the author points the main characteristics of these two sciences and their connections. After such explanations, he give examples of famous research in the field of ‘epidemiological criminology’. They show how many important issues in criminology has been neglected until the end of the twentieth century (evaluati...

  19. Social Anxiety Disorder and Alcohol Use Disorders

    Cuneyt Evren

    2010-01-01

    High rates of comorbidity were found between alcohol use disorders and social anxiety disorder in epidemiologic studies. Although many studies show strong relationship between social anxiety disorder and alcohol use disorder diagnosis, inconsistency about the causal relationship still remains. High rates of comorbidity is a subject of concern since patients with both alcohol use disorder and social anxiety disorder show more severe symptoms and more functional impairment than those patients w...

  20. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition

    Murray, C.J.; Barber, R.M.; Foreman, K.J.; Geleijnse, J.M.

    2015-01-01

    Background The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age–sex grou

  1. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013 : quantifying the epidemiological transition

    Murray, Christopher J. L.; Barber, Ryan M.; Foreman, Kyle J.; Ozgoren, Ayse Abbasoglu; Abd-Allah, Foad; Abera, Semaw F.; Aboyans, Victor; Abraham, Jerry P.; Abubakar, Ibrahim; Abu-Raddad, Laith J.; Abu-Rmeileh, Niveen M.; Achoki, Tom; Ackerman, Ilana N.; Ademi, Zanfina; Adou, Arsene K.; Adsuar, Jose C.; Afshin, Ashkan; Agardh, Emilie E.; Alam, Sayed Saidul; Alasfoor, Deena; Albittar, Mohammed I.; Alegretti, Miguel A.; Alemu, Zewdie A.; Alfonso-Cristancho, Rafael; Alhabib, Samia; Ali, Raghib; Alla, Francois; Allebeck, Peter; Almazroa, Mohammad A.; Alsharif, Ubai; Alvarez, Elena; Alvis-Guzman, Nelson; Amare, Azmeraw T.; Ameh, Emmanuel A.; Amini, Heresh; Ammar, Walid; Anderson, H. Ross; Anderson, Benjamin O.; Antonio, Carl Abelardo T.; Anwari, Palwasha; Arnlov, Johan; Arsenijevic, Valentina S. Arsic; Artaman, Al; Asghar, Rana J.; Assadi, Reza; Atkins, Lydia S.; Avila, Marco A.; Awuah, Baffour; Bachman, Victoria F.; Badawi, Alaa; Bahit, Maria C.; Balakrishnan, Kalpana; Banerjee, Amitava; Barker-Collo, Suzanne L.; Barquera, Simon; Barregard, Lars; Barrero, Lope H.; Basu, Arindam; Basu, Sanjay; Basulaiman, Mohammed O.; Beardsley, Justin; Bedi, Neeraj; Beghi, Ettore; Bekele, Tolesa; Bell, Michelle L.; Benjet, Corina; Bennett, Derrick A.; Bensenor, Isabela M.; Benzian, Habib; Bernabe, Eduardo; Bertozzi-Villa, Amelia; Beyene, Tariku J.; Bhala, Neeraj; Bhalla, Ashish; Bhutta, Zulfiqar A.; Bienhoff, Kelly; Bikbov, Boris; Biryukov, Stan; Blore, Jed D.; Blosser, Christopher D.; Blyth, Fiona M.; Bohensky, Megan A.; Bolliger, Ian W.; Basara, Berrak Bora; Bornstein, Natan M.; Bose, Dipan; Boufous, Soufiane; Bourne, Rupert R. A.; Boyers, Lindsay N.; Brainin, Michael; Brayne, Carol E.; Brazinova, Alexandra; Breitborde, Nicholas J. K.; Brenner, Hermann; Briggs, Adam D.; Brooks, Peter M.; Brown, Jonathan C.; Brugha, Traolach S.; Buchbinder, Rachelle; Buckle, Geoffrey C.; Budke, Christine M.; Bulchis, Anne; Bulloch, Andrew G.; Campos-Nonato, Ismael R.; Carabin, Helene; Carapetis, Jonathan R.; Cardenas, Rosario; Carpenter, David O.; Caso, Valeria; Castaneda-Orjuela, Carlos A.; Castro, Ruben E.; Catala-Lopez, Ferran; Cavalleri, Fiorella; Cavlin, Alanur; Chadha, Vineet K.; Chang, Jung-Chen; Charlson, Fiona J.; Chen, Honglei; Chen, Wanqing; Chiang, Peggy P.; Chimed-Ochir, Odgerel; Chowdhury, Rajiv; Christensen, Hanne; Christophi, Costas A.; Cirillo, Massimo; Coates, Matthew M.; Coffeng, Luc E.; Coggeshall, Megan S.; Colistro, Valentina; Colquhoun, Samantha M.; Cooke, Graham S.; Cooper, Cyrus; Cooper, Leslie T.; Coppola, Luis M.; Cortinovis, Monica; Criqui, Michael H.; Crump, John A.; Cuevas-Nasu, Lucia; Danawi, Hadi; Dandona, Lalit; Dandona, Rakhi; Dansereau, Emily; Dargan, Paul I.; Davey, Gail; Davis, Adrian; Davitoiu, Dragos V.; Dayama, Anand; De Leo, Diego; Degenhardt, Louisa; Del Pozo-Cruz, Borja; Dellavalle, Robert P.; Deribe, Kebede; Derrett, Sarah; Des Jarlais, Don C.; Dessalegn, Muluken; Dharmaratne, Samath D.; Dherani, Mukesh K.; Diaz-Torne, Cesar; Dicker, Daniel; Ding, Eric L.; Dokova, Klara; Dorsey, E. Ray; Driscoll, Tim R.; Duan, Leilei; Duber, Herbert C.; Ebel, Beth E.; Edmond, Karen M.; Elshrek, Yousef M.; Endres, Matthias; Ermakov, Sergey P.; Erskine, Holly E.; Eshrati, Babak; Esteghamati, Alireza; Estep, Kara; Faraon, Emerito Jose A.; Farzadfar, Farshad; Fay, Derek F.; Feigin, Valery L.; Felson, David T.; Fereshtehnejad, Seyed-Mohammad; Fernandes, Jefferson G.; Ferrari, Alize J.; Fitzmaurice, Christina; Flaxman, Abraham D.; Fleming, Thomas D.; Foigt, Nataliya; Forouzanfar, Mohammad H.; Fowkes, F. Gerry R.; Paleo, Urbano Fra; Franklin, Richard C.; Fuerst, Thomas; Gabbe, Belinda; Gaffikin, Lynne; Gankpe, Fortune G.; Geleijnse, Johanna M.; Gessner, Bradford D.; Gething, Peter; Gibney, Katherine B.; Giroud, Maurice; Giussani, Giorgia; Gomez Dantes, Hector; Gona, Philimon; Gonzalez-Medina, Diego; Gosselin, Richard A.; Gotay, Carolyn C.; Goto, Atsushi; Gouda, Hebe N.; Graetz, Nicholas; Gugnani, Harish C.; Gupta, Rahul; Gupta, Rajeev; Gutierrez, Reyna A.; Haagsma, Juanita; Hafezi-Nejad, Nima; Hagan, Holly; Halasa, Yara A.; Hamadeh, Randah R.; Hamavid, Hannah; Hammami, Mouhanad; Hancock, Jamie; Hankey, Graeme J.; Hansen, Gillian M.; Hao, Yuantao; Harb, Hilda L.; Maria Haro, Josep; Havmoeller, Rasmus; Hay, Simon I.; Hay, Roderick J.; Heredia-Pi, Ileana B.; Heuton, Kyle R.; Heydarpour, Pouria; Higashi, Hideki; Hijar, Martha; Hoek, Hans W.; Hoffman, Howard J.; Hosgood, H. Dean; Hossain, Mazeda; Hotez, Peter J.; Hoy, Damian G.; Hsairi, Mohamed; Hu, Guoqing; Huang, Cheng; Huang, John J.; Husseini, Abdullatif; Huynh, Chantal; Iannarone, Marissa L.; Iburg, Kim M.; Innos, Kaire; Inoue, Manami; Islami, Farhad; Jacobsen, Kathryn H.; Jarvis, Deborah L.; Jassal, Simerjot K.; Jee, Sun Ha; Jeemon, Panniyammakal; Jensen, Paul N.; Jha, Vivekanand; Jiang, Guohong; Jiang, Ying; Jonas, Jost B.; Juel, Knud; Kan, Haidong; Karch, Andre; Karema, Corine K.; Karimkhani, Chante; Karthikeyan, Ganesan; Kassebaum, Nicholas J.; Kaul, Anil; Kawakami, Norito; Kazanjan, Konstantin; Kemp, Andrew H.; Kengne, Andre P.; Keren, Andre; Khader, Yousef S.; Khalifa, Shams Eldin A.; Khan, Ejaz A.; Khan, Gulfaraz; Khang, Young-Ho; Kieling, Christian; Kim, Daniel; Kim, Sungroul; Kim, Yunjin; Kinfu, Yohannes; Kinge, Jonas M.; Kivipelto, Miia; Knibbs, Luke D.; Knudsen, Ann Kristin; Kokubo, Yoshihiro; Kosen, Soewarta; Krishnaswami, Sanjay; Defo, Barthelemy Kuate; Bicer, Burcu Kucuk; Kuipers, Ernst J.; Kulkarni, Chanda; Kulkarni, Veena S.; Kumar, G. Anil; Kyu, Hmwe H.; Lai, Taavi; Lalloo, Ratilal; Lallukka, Tea; Lam, Hilton; Lan, Qing; Lansingh, Van C.; Larsson, Anders; Lawrynowicz, Alicia E. B.; Leasher, Janet L.; Leigh, James; Leung, Ricky; Levitz, Carly E.; Li, Bin; Li, Yichong; Li, Yongmei; Lim, Stephen S.; Lind, Maggie; Lipshultz, Steven E.; Liu, Shiwei; Liu, Yang; Lloyd, Belinda K.; Lofgren, Katherine T.; Logroscino, Giancarlo; Looker, Katharine J.; Lortet-Tieulent, Joannie; Lotufo, Paulo A.; Lozano, Rafael; Lucas, Robyn M.; Lunevicius, Raimundas; Lyons, Ronan A.; Ma, Stefan; Macintyre, Michael F.; Mackay, Mark T.; Majdan, Marek; Malekzadeh, Reza; Marcenes, Wagner; Margolis, David J.; Margono, Christopher; Marzan, Melvin B.; Masci, Joseph R.; Mashal, Mohammad T.; Matzopoulos, Richard; Mayosi, Bongani M.; Mazorodze, Tasara T.; Mcgill, Neil W.; Mcgrath, John J.; Mckee, Martin; McLain, Abigail; Meaney, Peter A.; Medina, Catalina; Mehndiratta, Man Mohan; Mekonnen, Wubegzier; Melaku, Yohannes A.; Meltzer, Michele; Memish, Ziad A.; Mensah, George A.; Meretoja, Atte; Mhimbira, Francis A.; Micha, Renata; Miller, Ted R.; Mills, Edward J.; Mitchell, Philip B.; Mock, Charles N.; Ibrahim, Norlinah Mohamed; Mohammad, Karzan A.; Mokdad, Ali H.; Mola, Glen L. D.; Monasta, Lorenzo; Montanez Hernandez, Julio C.; Montico, Marcella; Montine, Thomas J.; Mooney, Meghan D.; Moore, Ami R.; Moradi-Lakeh, Maziar; Moran, Andrew E.; Mori, Rintaro; Moschandreas, Joanna; Moturi, Wilkister N.; Moyer, Madeline L.; Mozaffarian, Dariush; Msemburi, William T.; Mueller, Ulrich O.; Mukaigawara, Mitsuru; Mullany, Erin C.; Murdoch, Michele E.; Murray, Joseph; Murthy, Kinnari S.; Naghavi, Mohsen; Naheed, Aliya; Naidoo, Kovin S.; Naldi, Luigi; Nand, Devina; Nangia, Vinay; Narayan, K. M. Venkat; Nejjari, Chakib; Neupane, Sudan P.; Newton, Charles R.; Ng, Marie; Ngalesoni, Frida N.; Nguyen, Grant; Nisar, Muhammad I.; Nolte, Sandra; Norheim, Ole F.; Norman, Rosana E.; Norrving, Bo; Nyakarahuka, Luke; Oh, In-Hwan; Ohkubo, Takayoshi; Ohno, Summer L.; Olusanya, Bolajoko O.; Opio, John Nelson; Ortblad, Katrina; Ortiz, Alberto; Pain, Amanda W.; Pandian, Jeyaraj D.; Panelo, Carlo Irwin A.; Papachristou, Christina; Park, Eun-Kee; Park, Jae-Hyun; Patten, Scott B.; Patton, George C.; Paul, Vinod K.; Pavlin, Boris I.; Pearce, Neil; Pereira, David M.; Perez-Padilla, Rogelio; Perez-Ruiz, Fernando; Perico, Norberto; Pervaiz, Aslam; Pesudovs, Konrad; Peterson, Carrie B.; Petzold, Max; Phillips, Michael R.; Phillips, Bryan K.; Phillips, David E.; Piel, Frederic B.; Plass, Dietrich; Poenaru, Dan; Polinder, Suzanne; Pope, Daniel; Popova, Svetlana; Poulton, Richie G.; Pourmalek, Farshad; Prabhakaran, Dorairaj; Prasad, Noela M.; Pullan, Rachel L.; Qato, Dima M.; Quistberg, D. Alex; Rafay, Anwar; Rahimi, Kazem; Rahman, Sajjad U.; Raju, Murugesan; Rana, Saleem M.; Razavi, Homie; Reddy, K. Srinath; Refaat, Amany; Remuzzi, Giuseppe; Resnikoff, Serge; Ribeiro, Antonio L.; Richardson, Lee; Richardus, Jan Hendrik; Roberts, D. Allen; Rojas-Rueda, David; Ronfani, Luca; Roth, Gregory A.; Rothenbacher, Dietrich; Rothstein, David H.; Rowley, Jane T.; Roy, Nobhojit; Ruhago, George M.; Saeedi, Mohammad Y.; Saha, Sukanta; Sahraian, Mohammad Ali; Sampson, Uchechukwu K. A.; Sanabria, Juan R.; Sandar, Logan; Santos, Itamar S.; Satpathy, Maheswar; Sawhney, Monika; Scarborough, Peter; Schneider, Ione J.; Schoettker, Ben; Schumacher, Austin E.; Schwebel, David C.; Scott, James G.; Seedat, Soraya; Sepanlou, Sadaf G.; Serina, Peter T.; Servan-Mori, Edson E.; Shackelford, Katya A.; Shaheen, Amira; Shahraz, Saeid; Levy, Teresa Shamah; Shangguan, Siyi; She, Jun; Sheikhbahaei, Sara; Shi, Peilin; Shibuya, Kenji; Shinohara, Yukito; Shiri, Rahman; Shishani, Kawkab; Shiue, Ivy; Shrime, Mark G.; Sigfusdottir, Inga D.; Silberberg, Donald H.; Simard, Edgar P.; Sindi, Shireen; Singh, Abhishek; Singh, Jasvinder A.; Singh, Lavanya; Skirbekk, Vegard; Slepak, Erica Leigh; Sliwa, Karen; Soneji, Samir; Soreide, Kjetil; Soshnikov, Sergey; Sposato, Luciano A.; Sreeramareddy, Chandrashekhar T.; Stanaway, Jeffrey D.; Stathopoulou, Vasiliki; Stein, Dan J.; Stein, Murray B.; Steiner, Caitlyn; Steiner, Timothy J.; Stevens, Antony; Stewart, Andrea; Stovner, Lars J.; Stroumpoulis, Konstantinos; Sunguya, Bruno F.; Swaminathan, Soumya; Swaroop, Mamta; Sykes, Bryan L.; Tabb, Karen M.; Takahashi, Ken; Tandon, Nikhil; Tanne, David; Tanner, Marcel; Tavakkoli, Mohammad; Taylor, Hugh R.; Te Ao, Braden J.; Tediosi, Fabrizio; Temesgen, Awoke M.; Templin, Tara; Ten Have, Margreet; Tenkorang, Eric Y.; Terkawi, Abdullah S.; Thomson, Blake; Thorne-Lyman, Andrew L.; Thrift, Amanda G.; Thurston, George D.; Tillmann, Taavi; Tonelli, Marcello; Topouzis, Fotis; Toyoshima, Hideaki; Traebert, Jefferson; Tran, Bach X.; Trillini, Matias; Truelsen, Thomas; Tsilimbaris, Miltiadis; Tuzcu, Emin M.; Uchendu, Uche S.; Ukwaja, Kingsley N.; Undurraga, Eduardo A.; Uzun, Selen B.; Van Brakel, Wim H.; Van De Vijver, Steven; van Gool, Coen H.; Van Os, Jim; Vasankari, Tommi J.; Venketasubramanian, N.; Violante, Francesco S.; Vlassov, Vasiliy V.; Vollset, Stein Emil; Wagner, Gregory R.; Wagner, Joseph; Waller, Stephen G.; Wan, Xia; Wang, Haidong; Wang, Jianli; Wang, Linhong; Warouw, Tati S.; Weichenthal, Scott; Weiderpass, Elisabete; Weintraub, Robert G.; Wang Wenzhi, [Unknown; Werdecker, Andrea; Westerman, Ronny; Whiteford, Harvey A.; Wilkinson, James D.; Williams, Thomas N.; Wolfe, Charles D.; Wolock, Timothy M.; Woolf, Anthony D.; Wulf, Sarah; Wurtz, Brittany; Xu, Gelin; Yan, Lijing L.; Yano, Yuichiro; Ye, Pengpeng; Yentur, Goekalp K.; Yip, Paul; Yonemoto, Naohiro; Yoon, Seok-Jun; Younis, Mustafa Z.; Yu, Chuanhua; Zaki, Maysaa E.; Zhao, Yong; Zheng, Yingfeng; Zonies, David; Zou, Xiaonong; Salomon, Joshua A.; Lopez, Alan D.; Vos, Theo

    2015-01-01

    Background The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age-sex grou

  2. Environmental epidemiology

    Kopfler, F.C.; Craun, G.F. (eds.)

    1986-01-01

    This volume is a compendium of peer-reviewed papers presented at the Symposium on Exposure Measurement and Evaluation Methods for Epidemiology, cosponsored in 1985 by the Health Effects Research Laboratory, USEPA, and the Division of Environmental Chemistry of the American Chemical Society. The book is divided into four sections: Use of Biological Monitoring to Assess Exposure, Epidemiologic Considerations for Assessing Exposure, Health and Exposure Data Bases, and Assessment of Exposure to Environmental Contaminants for Epidemiologic Studies. Both background papers and detailed reports of human studies are presented. The Biological Monitoring section contains reports of efforts to quantify adducts in blood and urine samples. In the section on Epidemiologic Considerations the feasibility of conducting epidemiologic studies of persons residing near hazardous waste sites and those exposed to arsenic in drinking water is described. The review of Data Bases includes government and industry water quality monitoring systems, the FDA Market Basket Study, major EPA air monitoring data, the National Database on Body Burden of Toxic chemicals, and the National Human Adipose Tissue Survey. Methods of assessing current exposure and estimating past exposure are detailed in the final section. Exposure to trichloroethylene in shower water, the relationship between water quality and cardiovascular disease, the contribution of environmental lead exposures to pediatric blood lead levels, and data from the TEAM study in which researchers compare indoor, outdoor, and breath analysis of air pollutant exposures are also discussed.

  3. Epidemiology of male breast cancer.

    Weiss, Joli R; Moysich, Kirsten B; Swede, Helen

    2005-01-01

    Breast cancer in men is a rare disease, accounting for approximately 1% of all breast cancer cases. Although the epidemiologic literature regarding female breast cancer is extensive, relatively little is known about the etiology of male breast cancer (MBC). This review is intended to summarize the existing body of evidence on genetic and epidemiologic risk factors for breast cancer in men. Overall, the epidemiology of MBC presents similarities with the epidemiology of female breast cancer. Major genetic factors associated with an increased risk of breast cancer for men include BRCA2 mutations, which are believed to account for the majority of inherited breast cancer in men, Klinefelter syndrome, and a positive family history. Suspected genetic factors include AR gene mutations, CYP17 polymorphism, Cowden syndrome, and CHEK2. Epidemiologic risk factors for MBC include disorders relating to hormonal imbalances, such as obesity, testicular disorders (e.g., cryptorchidism, mumps orchitis, and orchiectomy), and radiation exposure. Suspected epidemiologic risk factors include prostate cancer,prostate cancer treatment, gynecomastia, occupational exposures (e.g., electromagnetic fields, polycyclic aromatic hydrocarbons, and high temperatures), dietary factors (e.g., meat intake and fruit and vegetable consumption), and alcohol intake. PMID:15668471

  4. Gynaekologisk epidemiologi

    Lidegaard, Øjvind

    2006-01-01

    Epidemiological research has good possibilities in Denmark due to the fact that all people have a personal PIN code and due to our many National health registers. In gynaecology the National Register of Patients, the Birth Registry, IVF-registry, Cancer Registry and latest the National Prescription...... Database offer unique possibilities of linking exposure data with many clinical outcomes. Danish epidemiology has contributed with morbidity analyses on children concieved by in vitro fertilisation, pharmacoepidemiological studies on short and long term effects of oral contraceptives and hormone therapy...

  5. A study on epidemiological profile of anxiety disorders among people living with HIV/AIDS in a sub-Saharan Africa HIV clinic.

    Olagunju, Andrew T; Adeyemi, Joseph D; Ogbolu, Raphael E; Campbell, Elizabeth A

    2012-11-01

    The aim of this study is to find out the prevalence, types and correlates of anxiety disorders among people living with HIV/AIDS (PLWHA) attending a sub-Saharan Africa HIV clinic. Three hundred HIV positive adults were subjected to semi-structured clinical interview using the Schedule for Clinical Assessment in Neuropsychiatry to diagnose anxiety disorders in them. Additionally, a socio-demographic/clinical profile questionnaire designed for the study was administered to the study participants. The prevalence of anxiety disorders among PLWHA in this study was 21.7 %, and anxiety disorder unspecified (6.2 %), mixed anxiety-depressive disorder (5.3 %) and social phobia (4 %) among others were the subtypes of anxiety disorders elicited among the participants. Lack of family support [correlation coefficient (r) = 0.212, P unemployment (r = 0.168, P = 0.004) and being unmarried (r = 0.182, P = 0.002) were much more likely to be found among participants with anxiety disorders; while younger age group (r = -0.126, P = 0.039) and negative previous mental illness (r = -0.894, P = 0.021) seem protective against anxiety disorders in this study. Our findings suggest a high burden of anxiety disorders among PLWHA and up to five-folds when compared to the general population. Thus, integration of proactive mental health screening as well as treatment services with inclusion of targeted intervention for anxiety disorders among PLWHA is recommended. PMID:22772942

  6. Salary adjustments

    HR Department

    2008-01-01

    In accordance with decisions taken by the Finance Committee and Council in December 2007, salaries are adjusted with effect from 1 January 2008. Scale of basic salaries and scale of stipends paid to fellows (Annex R A 5 and R A 6 respectively): increased by 0.71% with effect from 1 January 2008. As a result of the stability of the Geneva consumer price index, the following elements do not increase: a)\tFamily Allowance, Child Allowance and Infant Allowance (Annex R A 3); b)\tReimbursement of education fees: maximum amounts of reimbursement (Annex R A 4.01) for the academic year 2007/2008. Related adjustments will be applied, wherever applicable, to Paid Associates and Students. As in the past, the actual percentage increase of each salary position may vary, due to the application of a constant step value and rounding effects. Human Resources Department Tel. 73566

  7. Salary adjustments

    HR Department

    2008-01-01

    In accordance with decisions taken by the Finance Committee and Council in December 2007, salaries are adjusted with effect from 1 January 2008. Scale of basic salaries and scale of stipends paid to fellows (Annex R A 5 and R A 6 respectively): increased by 0.71% with effect from 1 January 2008. As a result of the stability of the Geneva consumer price index, following elements do not increase: a) Family Allowance, Child Allowance and Infant Allowance (Annex R A 3). b) Reimbursement of education fees: maximum amounts of reimbursement (Annex R A 4.01) for the academic year 2007/2008. Related adjustments will be implemented, wherever applicable, to Paid Associates and Students. As in the past, the actual percentage increase of each salary position may vary, due to the application of a constant step value and the rounding effects. Human Resources Department Tel. 73566

  8. The current status and influencing factors of work adjustment disorder among reemployment nurses%再就业护士工作适应障碍现状及其影响因素分析

    李英; 戴新娟; 段培蓓; 顾平

    2015-01-01

    目的:调查了解再就业护士工作适应障碍现状并分析其影响因素。方法:采用工作适应障碍量表、组织支持感量表、护士压力源量表及护士职业认同量表对江苏省某三级甲等医院74名有其他医院护理工作经验,离职后至该医院再次就业并且工作满半年的再就业护士进行问卷调查。结果:再就业护士的工作适应障碍总分为(22.60±3.74)分,高于国内常模;多元回归分析显示,护士工作压力源、变动工作频次是再就业护士工作适应障碍的影响因素。结论:护理管理者应分析再就业护士工作压力源的由来,采取针对性措施,以降低再就业护士的工作压力,提高再就业护士对新医院和新工作的满意度与忠诚度,降低离职率。%Objective:To investigate the current status and influencing factors of work adjustment disorder among reemployment nurses. Methods:Totally 74 reemployment nurses who worked in a tertiary Grade A hospital in Jiangsu province for over half a year were recruited and interviewed by the Work Adjustment Disorder Scale, Organizational Citizenship Behavior Scale, Nurse Stressors Scale, and Nurse Career Identity Scale. Results:The mean score of work adjustment disorder among reemployment nurses was (22.60±3.74). Multiple linear regression analysis showed that nurse working stressors and job-hopping frequency were the predictors of work adjustment disorder among reemployment nurses. Conclusion:Nursing managers should analyze the reasons of working stressors among reemployment nurses, take effective measures to reduce their stress, pay attention to cultivate reemployment nurses' satisfaction and loyalty to the hospital and decrease their job-hopping frequency.

  9. Adjustable collimator

    In a rotating fan beam tomographic scanner there is included an adjustable collimator and shutter assembly. The assembly includes a fan angle collimation cylinder having a plurality of different length slots through which the beam may pass for adjusting the fan angle of the beam. It also includes a beam thickness cylinder having a plurality of slots of different widths for adjusting the thickness of the beam. Further, some of the slots have filter materials mounted therein so that the operator may select from a plurality of filters. Also disclosed is a servo motor system which allows the operator to select the desired fan angle, beam thickness and filter from a remote location. An additional feature is a failsafe shutter assembly which includes a spring biased shutter cylinder mounted in the collimation cylinders. The servo motor control circuit checks several system conditions before the shutter is rendered openable. Further, the circuit cuts off the radiation if the shutter fails to open or close properly. A still further feature is a reference radiation intensity monitor which includes a tuning-fork shaped light conducting element having a scintillation crystal mounted on each tine. The monitor is placed adjacent the collimator between it and the source with the pair of crystals to either side of the fan beam

  10. DSM-IV criteria-based clinical subtypes of cannabis use disorders: Results from the National Epidemiological Survey on Alcohol and Related Conditions (NESARC)☆

    Blanco, Carlos; Ogburn, Elizabeth; de los Cobos, José Pérez; Lujan, Juan; Nunes, Edward V.; Grant, Bridget; Liu, Shang-Min; Hasin, Deborah S.

    2008-01-01

    Prior research documented high homogeneity of alcohol use disorders (AUDs) as clinical entities. However, it is unknown whether this finding extends to other substance use disorders. We investigated this by examining the prevalence of all possible DSM-IV criteria-based clinical subtypes of current and lifetime cannabis use disorders in the general population. The number of possible (i.e., theoretical) clinical subtypes of cannabis abuse and dependence based on different combinations of the DS...

  11. A Best Evidence Synthesis of Literacy Instruction on the Social Adjustment of Students with or At-Risk for Behavior Disorders

    Nelson, J. Ron; Lane, Kathleen L.; Benner, Gregory J.; Kim, Ockjean

    2011-01-01

    The findings of a best-evidence synthesis of the collateral effect of literacy instruction on the social adjustment of students are reported. The goal of the synthesis was to extend the work of Wanzek, Vaughn, Kim, and Cavanaugh (2006) by (a) reviewing treatment-outcomes conducted using group design methodology; (b) focusing on a more defined set…

  12. ANXIETY DISORDERS: A REVIEW

    Arya Ashwani; Kumar Tarun; Malik Ajay; Hooda Anil

    2011-01-01

    Anxiety disorders are a highly prevalent and disabling class of psychiatric disorders. Anxiety disorders are highly prevalent and associated with substantial distress, morbidity and mortality. Recent epidemiological studies of anxiety disorders provided evidence of their high frequency in the general population worldwide. Anxiety disorders afflict an estimated 15.7 million people in the United States each year. Anxiety disorders are highly prevalent in adults with females showing higher prepo...

  13. Digital epidemiology.

    Marcel Salathé

    Full Text Available Mobile, social, real-time: the ongoing revolution in the way people communicate has given rise to a new kind of epidemiology. Digital data sources, when harnessed appropriately, can provide local and timely information about disease and health dynamics in populations around the world. The rapid, unprecedented increase in the availability of relevant data from various digital sources creates considerable technical and computational challenges.

  14. Substance Use Disorders and Anxiety: A Treatment Challenge for Social Workers

    Brady, Kathleen T.; Haynes, Louise F.; Hartwell, Karen J.; KILLEEN, THERESE K.

    2013-01-01

    Converging evidence from epidemiologic and treatment studies indicate that anxiety disorders and substance use disorders commonly co-occur, and the interaction is multifaceted and variable. Epidemiological studies and investigations within clinical substance abuse populations have found an association between anxiety disorders and substance use disorders. Specific anxiety disorders including generalized anxiety disorder, panic disorder, and post traumatic stress disorder have all been associa...

  15. Prevalence and Axis I Comorbidity of Full and Partial Posttraumatic Stress Disorder in the United States: Results from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions

    Pietrzak, Robert H.; Goldstein, Risë B.; Southwick, Steven M.; Grant, Bridget F.

    2010-01-01

    The present study used data from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions (n=34,653) to examine lifetime Axis I psychiatric comorbidity of posttraumatic stress disorder (PTSD) in a nationally representative sample of U.S. adults. Lifetime prevalences±standard errors of PTSD and partial PTSD were 6.4%±0.18 and 6.6%±0.18, respectively. Rates of PTSD and partial PTSD were higher among women (8.6%±0.26 and 8.6%±0.26) than men (4.1%±0.19 and 4.5%±0.21). Respondent...

  16. Detecting disease-associated genes with confounding variable adjustment and the impact on genomic meta-analysis: With application to major depressive disorder

    Wang Xingbin; Lin Yan; Song Chi; Sibille Etienne; Tseng George C

    2012-01-01

    Abstract Background Detecting candidate markers in transcriptomic studies often encounters difficulties in complex diseases, particularly when overall signals are weak and sample size is small. Covariates including demographic, clinical and technical variables are often confounded with the underlying disease effects, which further hampers accurate biomarker detection. Our motivating example came from an analysis of five microarray studies in major depressive disorder (MDD), a heterogeneous ps...

  17. Family function, Parenting Style and Broader Autism Phenotype as Predicting Factors of Psychological Adjustment in Typically Developing Siblings of Children with Autism Spectrum Disorders.

    Mohammadreza Mohammadi; Hadi Zarafshan

    2014-01-01

    Objective Siblings of children with autism are at a greater risk of experiencing behavioral and social problems. Previous researches had focused on environmental variables such as family history of autism spectrum disorders (ASDs), behavior problems in the child with an ASD, parental mental health problems, stressful life events and “broader autism phenotype” (BAP), while variables like parenting style and family function that are shown to influence children’s behavioral and psychosocial adju...

  18. Mood Disorders after TBI

    Jorge, Ricardo E.; Arciniegas, David B

    2014-01-01

    In this article, we will examine the epidemiology and risk factors for the development of the most common mood disorders observed in the aftermath of TBI: depressive disorders and bipolar spectrum disorders. We will describe the classification approach and diagnostic criteria proposed in the fifth edition of the Diagnostic and Statistical Manual for Mental Disorders (DSM-V). We will also examine the differential diagnosis of post-TBI mood disorders and describe the mainstay of the evaluation ...

  19. Epidemiological studies in psychosomatic medicine.

    Eastwood, M R

    1975-01-01

    The epidemiological triad of host, agent and environment used conceptually in infectious disease may serve as a model for psychosomatic disorders, despite the involvement of many more variables. There are major problems with diagnosis and measurement, however, and the term "psychosomatic" has several meanings. The two main senses are "specific" psychosomatic disorders and an ecological view of illness. The association between psychiatric and physical disorder has been examined in a variety of settings and the findings have suggested that there is a positive relationship. Despite considerable methodological and sampling difficulties in epidemiological research into psychosomatic illness, recent efforts have been made to overcome these. The results of ecological studies appear to be more consistent that those dealing with "specific" psychosomatic disorders and suggest that man has a general psychophysical propensity to disease. Although physical and mental illness do seem to be intimately linked, the reasons for "vulnerability" to illness and "clustering" of illness are obscure. The clarification of these areas appears to be the main task ahead for epidemiology in the field of psychosomatic medicine. PMID:773850

  20. Epidemiology of IBD

    ... disease (IBD) What is IBD? Addressing IBD Epidemiology Epidemiology of the IBD Recommend on Facebook Tweet Share ... 5:1424-9. 2 Loftus EV, Jr. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental ...

  1. A description of medical conditions in adults with autism spectrum disorder: A follow-up of the 1980s Utah/UCLA Autism Epidemiologic Study.

    Jones, Kyle B; Cottle, Kristina; Bakian, Amanda; Farley, Megan; Bilder, Deborah; Coon, Hilary; McMahon, William M

    2016-07-01

    This study describes medical conditions experienced by a population-based cohort of adults with autism spectrum disorder whose significant developmental concerns were apparent during childhood. As part of a 25-year outcome study of autism spectrum disorder in adulthood, medical histories were collected on 92 participants (N = 69 males) who were first ascertained as children in the mid-1980s, 11 of whom were deceased at the time of follow-up. Questionnaires queried medical symptoms, disorders, hospitalizations, surgeries, and medication use. Median age at follow-up was 36 years (range: 23.5-50.5 years), and intellectual disability co-occurred in 62%. The most common medical conditions were seizures, obesity, insomnia, and constipation. The median number of medical conditions per person was 11. Increased medical comorbidity was associated with female gender (p = 0.01) and obesity (p = 0.03), but not intellectual disability (p = 0.79). Adults in this cohort of autism spectrum disorder first ascertained in the 1980s experience a high number of chronic medical conditions, regardless of intellectual ability. Understanding of these conditions commonly experienced should direct community-based and medical primary care for this population. PMID:26162628

  2. Mathematical epidemiology

    Driessche, Pauline; Wu, Jianhong

    2008-01-01

    Based on lecture notes of two summer schools with a mixed audience from mathematical sciences, epidemiology and public health, this volume offers a comprehensive introduction to basic ideas and techniques in modeling infectious diseases, for the comparison of strategies to plan for an anticipated epidemic or pandemic, and to deal with a disease outbreak in real time. It covers detailed case studies for diseases including pandemic influenza, West Nile virus, and childhood diseases. Models for other diseases including Severe Acute Respiratory Syndrome, fox rabies, and sexually transmitted infections are included as applications. Its chapters are coherent and complementary independent units. In order to accustom students to look at the current literature and to experience different perspectives, no attempt has been made to achieve united writing style or unified notation. Notes on some mathematical background (calculus, matrix algebra, differential equations, and probability) have been prepared and may be downlo...

  3. Adjustment to Cancer: Anxiety and Distress (PDQ®)—Health Professional Version

    Expert-reviewed information summary about the difficult emotional responses many cancer patients experience. This summary focuses on normal adjustment issues, psychosocial distress, and adjustment disorders.

  4. Epidemiology and Heritability of Major Depressive Disorder, Stratified by Age of Onset, Sex, and Illness Course in Generation Scotland: Scottish Family Health Study (GS:SFHS)

    Ana Maria Fernandez-Pujals; Mark James Adams; Pippa Thomson; McKechanie, Andrew G.; Blackwood, Douglas H.R.; Smith, Blair H; Dominiczak, Anna F.; Morris, Andrew D.; Keith Matthews; Archie Campbell; Pamela Linksted; Haley, Chris S.; Deary, Ian J; Porteous, David J.; MacIntyre, Donald J.

    2015-01-01

    The heritability of Major Depressive Disorder (MDD) has been estimated at 37% based largely on twin studies that rely on contested assumptions. More recently, the heritability of MDD has been estimated on large populations from registries such as the Swedish, Finnish, and Chinese cohorts. Family-based designs utilise a number of different relationships and provide an alternative means of estimating heritability. Generation Scotland: Scottish Family Health Study (GS:SFHS) is a large (n = 20,19...

  5. Epidemiological survey of generalized anxiety disorder in Yunfu City%云浮市广泛性焦虑障碍流行病学调查

    钟书铭; 肖垚南; 陈妙扬; 郑洪波; 张璐璐; 陈丁玲; 卢冬艳

    2015-01-01

    目的:了结云浮市15岁以上人群广泛性焦虑障碍的患病率及分布特点。方法采用初级单位含量比例分层整体随机抽样方法,以美国精神障碍诊断与统计手册第4版(DSM-Ⅳ)轴障碍定式临床检查患者版(SCID-Ⅰ/P)对全市5县区2373人进行入户面访调查。结果广泛性焦虑障碍的时点患病率为0.46%,其中男性为0.30%,女性为0.69%,该疾病与无业或失业状态关系密切,精神科就诊率为18.18%。结论广泛性焦虑障碍在云浮市患病率较高,就诊率较低,健全社区精神卫生服务有利于降低其发生发展。%Objective To describe the prevalence and distribution of generalized anxiety disorder among people aged above 15 years in Yunfu city. Methods A total of 2 373 subjects were randomly selected from 5 rural and rural-urban fringe zone by the elementary unit stratified cluster sampling method. They were assessed by face to face interview with United States Diagnostic and Statistical Manual of Mental Disorders 4th edition (DSM-Ⅳ) AxisⅠDisorders-style version of the clinical examination of patients (SCID-Ⅰ/P). Results The current prevalence of gen-eralized anxiety disorder was 0.46%. It was 0.30%of male and 0.69%of female. The disease was closely associated with unemployed status, and its rate of visiting the doctors was 18.8%. Conclusion The prevalence of generalized anxiety disorder in Yunfu city was relatively high, while the visiting rate was low. Occurrence and development of the disease could be reduced by improving mental health service.

  6. [Epidemiology of osteoporosis].

    Grazio, Simeon

    2006-01-01

    Osteoporosis represents a major and increasing public health problem with the aging of population. Major clinical consequences and economic burden of the disease are fractures. Many risk factors are associated with the fractures including low bone mass, hormonal disorders, personal and family history of fractures, low body weight, use of certain drugs (e.g. glucocorticoids), cigarette smoking, elevated intake of alchohol, low physical activity, insufficient level of vitamin D and low intake of calcium. This epidemiological review describes frequency, importance of risk factors and impact of osteoporosis and osteoporotic fractures. Objective measures of bone mineral density along with clinical assessment of risk factors can help identify patients who will benefit from prevention and intervention efforts and eventually reduce the morbidity and mortality associated with osteoporosis-related fractures. PMID:17580550

  7. Coccidioidomycosis: epidemiology

    Brown J

    2013-06-01

    Full Text Available Jennifer Brown,1 Kaitlin Benedict,2 Benjamin J Park,2 George R Thompson III1,31Department of Internal Medicine, Division of Infectious Diseases, University of California, Davis Medical Center, Sacramento, CA, USA; 2Mycotic Diseases Branch, Division of Foodborne, Waterborne, and Environmental Diseases, US Centers for Disease Control and Prevention, Atlanta, GA, USA; 3Department of Medical Microbiology and Immunology, One Shields Avenue, Tupper Hall, Coccidioidomycosis Serology Laboratory, University of California, Davis, CA, USAAbstract: Coccidioidomycosis consists of a spectrum of disease, ranging from a mild, self-limited, febrile illness to severe, life-threatening infection. It is caused by the soil-dwelling fungi, Coccidioides immitis and C. posadasii, which are present in diverse endemic areas. Climate changes and environmental factors affect the Coccidioides lifecycle and influence infection rates. The incidence of coccidioidomycosis has risen substantially over the past two decades. The vast majority of Coccidioides infections occur in the endemic zones, such as California, Arizona, Mexico, and Central America. Infections occurring outside those zones appear to be increasingly common, and pose unique clinical and public health challenges. It has long been known that elderly persons, pregnant women, and members of certain ethnic groups are at risk for severe or disseminated coccidioidomycosis. In recent years, it has become evident that persons with immunodeficiency diseases, diabetics, transplant recipients, and prisoners are also particularly vulnerable.Keywords: coccidioidomycosis, Coccidioides, epidemiology, incidence, risk factors, geography

  8. The epidemiology of inflammatory bowel disease

    Burisch, Johan; Munkholm, Pia

    2015-01-01

    significantly higher among IBD patients. CONCLUSION: In recent years, self-management and patient empowerment, combined with evolving eHealth solutions, has utilized epidemiological knowledge on disease patterns and has been improving compliance and the timing of adjusting therapies, thus optimizing efficacy by...

  9. Premorbid Adjustment Profiles in Psychosis and the Role of Familial Factors

    Quee, Piotr J.; Meijer, Julia H.; Islam, Md Atiqul; Aleman, Andre; Alizadeh, Behrooz Z.; Meijer, Carin J.; van den Heuvel, Edwin R.

    2014-01-01

    Disease heterogeneity in patients with psychotic disorder may be explained by distinct profiles of premorbid adjustment. The current study explored premorbid adjustment profiles in patients with psychotic disorders, associations with cognitive and clinical characteristics after disease onset, and th

  10. Premorbid adjustment profiles in psychosis and the role of familial factors

    Quee, Piotr J; Meijer, Julia H; Islam, Md Atiqul; Aleman, André; Alizadeh, Behrooz Z; Meijer, Carin J; van den Heuvel, Edwin R

    2014-01-01

    Disease heterogeneity in patients with psychotic disorder may be explained by distinct profiles of premorbid adjustment. The current study explored premorbid adjustment profiles in patients with psychotic disorders, associations with cognitive and clinical characteristics after disease onset, and th

  11. Epidemiologic Study of Consciousness Disorder in Burn Sepsis Patients%烧伤脓毒症患者意识障碍的流行病学分析

    孙羽飞; 徐文举

    2013-01-01

    Objective To discuss the causes,clinical features,related risk factors and outcome of sepsis patients after burns with consciousness disorder. Methods A retrospective study including 157 burn sepsis patients from 2011 to 2012 was conducted in our department of burn and plastic surgery. The baseline data of patients the causes for consciousness disorder,vital signs,biochemical indicators,related risk factors and outcome were analyzed in the study. Results The incidence of consciousness disorder in burn sepsis patients was 39.5%. The causes and the percentages were septic associated encephalopathy (46.8%)、 hypoxemia (25.8%)、 hypernatremia (11.3%)、hyponatremia(4.8%)、metabolic acidosis(4.8%)、Delayed encephalopathy after acute carbon monoxide poisoning(3.2%)、hypoglycemia(1.6%) and intracranial infection (1.6%). Conclusion The main causes for consciousness disorder in burn sepsis patients are septic associated encephalopathy and hypoxemia. Disorder of consciousness increases the mortality rate of burn sepsis patients,in addition , The mortality rate of septic associated encephalopathy was obviously higher than that of other causes.%目的探讨烧伤脓毒症患者合并意识障碍的原因、临床表现、相关危险因素及预后。方法回顾性分析我院烧伤整形科2011年01月~2012年12月收治的157例脓毒症患者的临床资料,分析其合并意识障碍的原因、临床表现、生化指标、相关危险因素及预后。结果烧伤脓毒症患者出现意识障碍的发生率为39.5%,原因和百分率分别为:SAE 29例(46.8%)、低氧血症16例(25.8%)、高钠血症7例(11.3%)、低钠血症3例(4.8%)、代谢性酸中毒3例(4.8%)、急性 CO中毒后迟发性脑病2例(3.2%)、低血糖1例(1.6%)、颅内感染1例(1.6%)。脓毒症合并意识障碍组与非意识障碍组在年龄、致伤原因、烧伤面积和深度上比较差异无统计学意义(P>0.05),意识障碍

  12. Epidemiology and Heritability of Major Depressive Disorder, Stratified by Age of Onset, Sex, and Illness Course in Generation Scotland: Scottish Family Health Study (GS:SFHS.

    Ana Maria Fernandez-Pujals

    Full Text Available The heritability of Major Depressive Disorder (MDD has been estimated at 37% based largely on twin studies that rely on contested assumptions. More recently, the heritability of MDD has been estimated on large populations from registries such as the Swedish, Finnish, and Chinese cohorts. Family-based designs utilise a number of different relationships and provide an alternative means of estimating heritability. Generation Scotland: Scottish Family Health Study (GS:SFHS is a large (n = 20,198, family-based population study designed to identify the genetic determinants of common diseases, including Major Depressive Disorder. Two thousand seven hundred and six individuals were SCID diagnosed with MDD, 13.5% of the cohort, from which we inferred a population prevalence of 12.2% (95% credible interval: 11.4% to 13.1%. Increased risk of MDD was associated with being female, unemployed due to a disability, current smokers, former drinkers, and living in areas of greater social deprivation. The heritability of MDD in GS:SFHS was between 28% and 44%, estimated from a pedigree model. The genetic correlation of MDD between sexes, age of onset, and illness course were examined and showed strong genetic correlations. The genetic correlation between males and females with MDD was 0.75 (0.43 to 0.99; between earlier (≤ age 40 and later (> age 40 onset was 0.85 (0.66 to 0.98; and between single and recurrent episodic illness course was 0.87 (0.72 to 0.98. We found that the heritability of recurrent MDD illness course was significantly greater than the heritability of single MDD illness course. The study confirms a moderate genetic contribution to depression, with a small contribution of the common family environment (variance proportion = 0.07, CI: 0.01 to 0.15, and supports the relationship of MDD with previously identified risk factors. This study did not find robust support for genetic differences in MDD due to sex, age of onset, or illness course. However

  13. Does routine child health surveillance contribute to the early detection of children with pervasive developmental disorders? – An epidemiological study in Kent, U.K.

    Ritchie Jane

    2004-03-01

    Full Text Available Abstract Background Recently changed guidelines for child health surveillance in the United Kingdom (U.K. suggest targeted checks only, instead of the previously conducted routine or universal screening at 2 years and 3.5 years. There are concerns that these changes could lead to a delay in the detection of children with autism and other pervasive developmental disorders (PDD. Recent U.K. studies have suggested that the prevalence of PDD is much higher than previously estimated. This study establishes to which extent the routine checks contributed to the early detection and assessment of cases of PDD. Simultaneously we have evaluated the process involved and estimate the prevalence of PDD in our district. Methods Retrospective study design utilising community medical files. Headteachers of schools (n = 75 within Maidstone district (Kent were asked to report all children with an established diagnosis of autism or PDD attending year 4 (born '91 and '92 / n = 2536 in October 2000 based on educational records. Results 59 schools (78.7% took part in the study. A total of 33 children were reported. 21 fulfilled the inclusion criteria (12 falsely reported. The prevalences were (per 10,000: PDD 82.8 (male to female ratio 6:1, childhood autism 23.7, Asperger's syndrome 11.8 and autistic spectrum disorder 47.3. Co-existing medical conditions were noted in 14.3%; 52.4% were attending mainstream schools. In 63.2% of cases concerns – mainly in the area of speech and language development (SLD – had been documented at the 2 year check. At the 3.5 year check concerns were noted in 94.1% – the main area was again SLD (76.5%, although behavioural abnormalities were becoming more frequent (47.1%. A total of 13 children (68.4% were referred for further assessment as a direct result of the checks. Conclusions The prevalences for different types of PDD were similar to figures published recently, but much higher than reported a few years ago. Analysis of our

  14. Adjustments and Depression

    Full Text Available ... to my SCI? How do I deal with depression and adjustment to my SCI? ☷ ▾ Page contents The ... the moment you are injured. Understanding adjustment and depression Adjustment to paralysis is a process of changing ...

  15. The epidemiology of acne vulgaris in late adolescence

    Lynn DD

    2016-01-01

    Full Text Available Darren D Lynn,1 Tamara Umari,1 Cory A Dunnick,2,3 Robert P Dellavalle2–4 1Department of Dermatology, University of Colorado School of Medicine, 2Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, 3Dermatology Service, US Department of Veterans Affairs, Eastern Colorado Health Care System, Denver, 4Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA Importance: Acne vulgaris is the most common skin condition affecting late adolescents across the globe. Although prior studies have evaluated epidemiologic patterns of acne vulgaris in various ethnicities and regions, adequate understanding of the worldwide burden of the disease associated with patients in their late adolescence (15–19-year olds remains lacking. Objective: To assess the global burden of the disease associated with acne vulgaris for late adolescents (15–19-year olds and provide an overview of the epidemiology, pathophysiology, and treatment options for acne in this population. Design: Database summary study. Setting: Global Burden of Disease Study 2010 database. Participants: Global Burden of Disease regions comprised countries with prevalence of acne vulgaris between the ages of 15 and 19 years. Main outcomes and measures: Geographic region-level disability-adjusted life year rates (per 100,000 persons associated with acne vulgaris in years 1990 through 2010. Median percentage change in disability-adjusted life year rates was estimated for each region across the specified study period. Conclusion and relevance: Acne vulgaris-associated disease burden exhibits global distribution and has continued to grow in prevalence over time within this population. This continued growth suggests an unmet dermatologic need worldwide for this disorder and potential opportunities for improved access and delivery of dermatologic care. Our analysis of the literature reveals numerous

  16. Quantifying psychiatric comorbidity - Lessions from chronic disease epidemiology

    Batstra, L; Bos, EH; Neeleman, J

    2002-01-01

    Background Comorbidity research in psychiatric epidemiology mostly uses measures of association like odds or risk ratios to express how strongly disorders are linked. In contrast, chronic disease epidemiologists increasingly use measures of clustering, like multimorbidity (cluster) coefficients, to

  17. Effect of group psychotherapy on remission of adjustment disorder in college freshmen%团体心理疗法缓解大学新生适应障碍

    邓旭阳; 郭晋林; 王小玲; 何壮湘; 李卉; 李辉; 姜婷娜

    2004-01-01

    背景:大学新生适应障碍严重影响其生活、学习和人际交往,较大样本的团体心理疗法治疗适应障碍研究未见报道.目的:探索运用团体心理疗法,缓解大学新生适应障碍的有效性.设计:回顾性研究.地点、对象和方法:采取心理测评量表(SCL-90)和心理门诊约谈,从南京某医学院1999,2000两个新生年级1 126名新生中随机抽样适应障碍新生各分一组,每组30人,运用团体疗法的基本技术,团体讨论、心理剧、放松练习等主要方法,结合自我评价表和心理量表前后对比研究.主要观察指标:大学新生在治疗前后心理健康和自我评价的变化.结果:①治疗前后,1999级新生分享经验(7.10±1.40,7.23±1.48)、信任自己(5.87±2.14,7.48±1.70)等差异有显著性或高度显著性意义(t=2.01,P<0.05,t=3.37,P<0.01);2000级新生分享经验等差异显著(t=2.41,P<0.05),喜欢参与的差异高度显著(t=3.05,P<0.01),关怀别人、信任自己等差异高度显著(t=5.01,4.12,P<0.001).②治疗前后,1999级新生躯体化、人际关系、抑郁、强迫、焦虑、恐怖和精神病性差异显著或高度显著(t=2.26~2.50,P<0.05;t=2.88~3.15,P<0.01);2000级新生躯体化、恐怖、抑郁方面差异显著或高度显著(t=2.67,2 10,P<0.05;t=2.94,P<0.01).③1999,2000级治疗前后自我评价同时比较,治疗前关怀别人、有责任感、了解别人的差异显著或高度显著(t=2.09,P<0.05;t=2.80,P<0.01;t=3.82,P<0.001);治疗后关怀别人、信任自己等4方面差异显著(t=2.47,2.17,P<0.01);心理健康同时相互比较,治疗前差异不显著,治疗后精神病性差异显著(t=2.09,P<0.05).结论:团体心理疗法是缓解大学新生适应障碍的有效途径,有助于大学新生心理健康状况和自我评价的积极改变.%BACKGROUND: Adjustment disorder of freshmen severely affeeted their lives, studies and interpersonal communications, but reports about the effect

  18. International Lymphoma Epidemiology Consortium

    The InterLymph Consortium, or formally the International Consortium of Investigators Working on Non-Hodgkin's Lymphoma Epidemiologic Studies, is an open scientific forum for epidemiologic research in non-Hodgkin's lymphoma.

  19. Ehrlichiosis: Statistics and Epidemiology

    ... a tick Diseases transmitted by ticks Statistics and Epidemiology Recommend on Facebook Tweet Share Compartir On this ... Holman RC, McQuiston JH, Krebs JW, Swerdlow DL. Epidemiology of human ehrlichiosis and anaplasmosis in the United ...

  20. Anaplasmosis: Statistics and Epidemiology

    ... a tick Diseases transmitted by ticks Statistics and Epidemiology Recommend on Facebook Tweet Share Compartir On this ... Holman RC, McQuiston JH, Krebs JW, Swerdlow DL. Epidemiology of human ehrlichiosis and anaplasmosis in the United ...

  1. Intermittent Explosive Disorder

    Lut Tamam

    2011-09-01

    Full Text Available Intermittent explosive disorder is an impulse control disorder characterized by the occurrence of discrete episodes of failure to resist aggressive impulses that result in violent assault or destruction of property. Though the prevalence intermittent explosive disorder has been reported to be relatively rare in frontier studies on the field, it is now common opinion that intermittent explosive disorder is far more common than previously thought especially in clinical psychiatry settings. Etiological studies displayed the role of both psychosocial factors like childhood traumas and biological factors like dysfunctional neurotransmitter systems and genetics. In differential diagnosis of the disorder, disorders involving agression as a symptom such as alcohol and drug intoxication, antisocial and borderline personality disorders, personality changes due to general medical conditions and behavioral disorder should be considered. A combination of pharmacological and psychotherapeutic approaches are suggested in the treatment of the disorder. This article briefly reviews the historical background, diagnostic criteria, epidemiology, etiology and treatment of intermittent explosive disorder.

  2. Cancer Epidemiology Matters Blog

    The Cancer Epidemiology Matters blog helps foster a dialogue between the National Cancer Institute's (NCI) Epidemiology and Genomics Research Program (EGRP), extramural researchers, and other individuals, such as clinicians, community partners, and advocates, who are interested in cancer epidemiology and genomics.

  3. Eating Disorders in Paraguayan Adolescents

    Ramirez, Maria E.; McIntosh, David E.; Kruczek, Theresa

    2013-01-01

    Eating disorders, once thought to be exclusively a disorder of the more affluent Western countries, are now spreading around the world. Despite the wealth of information on the prevalence of eating disorders in developed countries, epidemiological data for South America is scarce. The 26-item Eating Attitude Test (EAT-26) was used to explore the…

  4. Anxiety Disorders and Depression in Older Adults

    Hek, Karin

    2013-01-01

    textabstractAnxiety disorders and depression are common and complex disorders. Despite decades of research, their etiology is largely unknown. Study of the occurrence and determinants, i.e. the epidemiology of anxiety disorders and depression, helps unravel their etiology. This thesis examines the epidemiology of anxiety disorders and depression in older adults. In particular, comorbidity, health care use, cortisol and atherosclerosis and genetic factors are studied in relation to anxiety and...

  5. Sleep disorders and stroke

    Wallace, Douglas M; Ramos, Alberto R.; Rundek, Tatjana

    2012-01-01

    The purpose of this review is to highlight existing literature on the epidemiology, pathophysiology, and treatments of stroke sleep disorders. Stroke sleep disorders are associated with many intermediary vascular risk factors leading to stroke, but they may also influence these risk factors through direct or indirect mechanisms. Sleep disturbances may be further exacerbated by stroke or caused by stroke. Unrecognized and untreated sleep disorders may influence rehabilitation efforts and poor ...

  6. Epidemiological studies in mucus hypersecretion

    Vestbo, Jørgen

    2002-01-01

    hypothesis' it was reduced to being an innocent disorder in the 1980s but is now again recognized as a potential risk factor for an accelerated loss of lung function. Whereas early studies in mainly occupational cohorts showed no effect of chronic mucus hypersecretion on decline in lung function, such an...... presence of mucus. In asthma recent findings suggest that in epidemiology chronic mucus hypersecretion may indicate lack of control which leads to an accelerated loss of lung function and increased mortality in subjects with self-reported asthma....

  7. Epidemiology and burden of alopecia areata: a systematic review

    Villasante Fricke AC

    2015-07-01

    Full Text Available Alexandra C Villasante Fricke, Mariya MitevaDepartment of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USABackground: Alopecia areata (AA is an autoimmune disorder characterized by patches of non-scarring alopecia affecting scalp and body hair that can be psychologically devastating. AA is clinically heterogenous, and its natural history is unpredictable. There is no preventative therapy or cure.Objective: The objective of this study is to provide an evidence-based systematic review on the epidemiology and the burden of AA.Methods and selection criteria: A search was conducted of the published, peer-reviewed literature via PubMed, Embase, and Web of Science. Studies published in English within the last 51 years that measured AA’s incidence, prevalence, distribution, disability-adjusted life years (DALYs, quality of life, and associated psychiatric and medical comorbidities were included. Two authors assessed studies and extracted the data.Results: The lifetime incidence of AA is approximately 2% worldwide. Both formal population studies found no sex predominance. First onset is most common in the third and fourth decades of life but may occur at any age. An earlier age of first onset corresponds with an increased lifetime risk of extensive disease. Global DALYs for AA were calculated at 1,332,800 in 2010. AA patients are at risk for depression and anxiety, atopy, vitiligo, thyroid disease, and other autoimmune conditions.Conclusion: AA is the most prevalent autoimmune disorder and the second most prevalent hair loss disorder after androgenetic alopecia, and the lifetime risk in the global population is approximately 2%. AA is associated with psychiatric and medical comorbidities including depression, anxiety, and several autoimmune disorders, and an increased global burden of disease.Keywords: hair loss, hair, prevalence, incidence, burden of disease

  8. La Tourette's Disorder

    Gabriel Fernando Oviedo Lugo

    2004-08-01

    Full Text Available Tourette Syndrome (TS is a complex neuropsychiatric disorder in which tic symptoms emerge prior to age of 18 and have, at least, a minimum duration of 12 months. This disorder produces distress and impairs normal functioning; it has a well-known chronic-waxing and waning course. TS has several comorbid conditions like obsessive-compulsive disorder, attention deficit-hyperactivity disorder, and learning disorders, among others. This article will review the epidemiologic, etiologic and phenomenological concepts of the disease and its therapeutic perspectives.

  9. Binge Eating Disorder

    Senol Turan

    2015-12-01

    Full Text Available Binge Eating Disorder, characterized by frequent and persistent overeating episodes that are accompanied by feeling of loss of control over eating without regular compensatory behaviors and was identified in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition as a new eating disorder category. Binge Eating Disorder is the most common eating disorder among adults. Binge Eating Disorder is associated with significant morbidity, including medical complications related to obesity, eating disorder psychopathology, psychiatric comorbidity; reduced quality of life, and impaired social functioning. Current treatments of Binge Eating Disorder include pharmacotherapy, psychotherapy and bariatric surgery. In this review, the definition, epidemiology, etiology, clinical features, and also mainly treatment of Binge Eating Disorder are discussed.

  10. Racial-ethnic related clinical and neurocognitive differences in adults with gambling disorder.

    Chamberlain, Samuel R; Leppink, Eric; Redden, Sarah A; Odlaug, Brian L; Grant, Jon E

    2016-08-30

    Recent epidemiological data suggest that the lifetime prevalence of gambling problems differs depending on race-ethnicity. Understanding variations in disease presentation in blacks and whites, and relationships with biological and sociocultural factors, may have implications for selecting appropriate prevention strategies. 62 non-treatment seeking volunteers (18-29 years, n=18 [29.0%] female) with gambling disorder were recruited from the general community. Black (n=36) and White (n=26) participants were compared on demographic, clinical and cognitive measures. Young black adults with gambling disorder reported more symptoms of gambling disorder and greater scores on a measure of compulsivity. In addition they exhibited significantly higher total errors on a set-shifting task, less risk adjustment on a gambling task, greater delay aversion on a gambling task, and more total errors on a working memory task. These findings suggest that the clinical and neurocognitive presentation of gambling disorder different between racial-ethnic groups. PMID:27262266

  11. GI Disorders: Glossary of Terms

    ... biologic aspects of the disorder with the unique psychosocial features of the individual, and helps explain the ... in the number of eosinophils in the blood. Epidemiology The study of the distribution of health-related ...

  12. Identifying patients with myasthenia for epidemiological research by linkage of automated registers

    Pedersen, Emil Greve; Hallas, Jesper; Hansen, Klaus; Jensen, Poul Erik Hyldgaard; Gaist, David

    2011-01-01

    We validated a new method of identifying patients with incident myasthenia in automated Danish registers for the purpose of conducting epidemiological studies of the disorder.......We validated a new method of identifying patients with incident myasthenia in automated Danish registers for the purpose of conducting epidemiological studies of the disorder....

  13. Adjustments and Depression

    Full Text Available ... adjustment and depression Adjustment to paralysis is a process of changing one's thoughts and feelings and is ... stem cell research? What is the clinical trials process? Get support Ask us anything Get a peer ...

  14. Adjustments and Depression

    Full Text Available ... depression and adjustment to my SCI? How do I deal with depression and adjustment to my SCI? ☷ ▾ ... following an SCI? What are the secondary conditions? I have no health insurance, what are my options? ...

  15. Annual Adjustment Factors

    Department of Housing and Urban Development — The Department of Housing and Urban Development establishes the rent adjustment factors - called Annual Adjustment Factors (AAFs) - on the basis of Consumer Price...

  16. Adjustments and Depression

    Full Text Available ... course an adjustment period as you navigate your new normal. The most important point to remember is ... to rebuild one's identity and to find a new balance in relationships. The stages of adjustment can ...

  17. Environmental Epidemiology of Essential Tremor

    Louis, Elan D.

    2008-01-01

    Background Essential tremor (ET) is one of the most common neurological disorders. Despite this, the disease mechanisms and etiology are not well understood. While susceptibility genotypes undoubtedly underlie many ET cases, no ET genes have been identified thus far. As with many other progressive, degenerative neurological disorders, it is likely that environmental factors contribute to the etiology of ET. Environmental epidemiology is the study in specific populations or communities of the effect on human health of physical, biologic and chemical factors in the external environment. The purpose of this article is to review current knowledge with regards to the environmental epidemiology of ET. Results As will be discussed, a series of preliminary case-control studies in recent years has begun to explore several candidate toxins/exposures, including harmane (1-methyl-9H-pyrido[3,4-b]indole), lead and agricultural exposures/pesticides. Conclusions While several initial results are promising, as will be discussed, additional studies are needed to more definitively establish whether these exposures are associated with ET and if they are of etiological importance. PMID:18716411

  18. ANXIETY DISORDERS: A REVIEW

    Arya Ashwani

    2011-05-01

    Full Text Available Anxiety disorders are a highly prevalent and disabling class of psychiatric disorders. Anxiety disorders are highly prevalent and associated with substantial distress, morbidity and mortality. Recent epidemiological studies of anxiety disorders provided evidence of their high frequency in the general population worldwide. Anxiety disorders afflict an estimated 15.7 million people in the United States each year. Anxiety disorders are highly prevalent in adults with females showing higher preponderance of 2:1 as compared to males. Anxiety disorders are a group of mental disorders characterized by various combinations of key features - Irritability, fear, Insomnia, Nervousness, Tachycardia, Inability to concentrate, poor coping skills, Palpitation, Sweating, Agoraphobia and Social Withdrawal. The anxiety disorders, including panic disorder (PD, generalized anxiety disorder (GAD, social anxiety disorder (SAD, and posttraumatic stress disorder (PTSD, are among the disabling medical disorders. The neurobiology of anxiety disorders is not fully understood, but several different biologic abnormalities have been implicated in their etiology. The GABA, NE and 5HT systems play crucial roles in mediating the affective circuitry underlying the highly related clinical disorders of anxiety. Anxiety is a common psychiatric condition characterized by unnecessary aggression, poor quality of life, fear, worry, avoidance, and compulsive rituals that are associated with significant distress.

  19. Bipolar Disorder in Turkey

    Bulent Kadri Gultekin

    2014-06-01

    Full Text Available Assessment of studies related with bipolar disorder in Turkey did not reveal an epidemiologically qualified field study. Most of the studies are hospital based or clinical studies which did not include a systematical scanning and did not aim to collect any epidemiological data and transfer information to health authorities. The generalizability of these studies to our community is far from being valid and reliable. On the other hand, a profile which will be created by reviewing the findings of these studies performed in various regions of Turkey will have a contribution to knowing the and ldquo;unique to us and rdquo; features of bipolar disorder and determining cultural risk factors. All this information can constitute a basis for formation and development of public mental health services related with bipolar disorder. In Turkey, the need for epidemiologically significant, polycentric, public sampled studies with broad participation is indispensable. Although our psychiatric epidemiology and clinical studies include necessary scientific basis, they are not powerful enough to evaluate the authentic and progressional relations such as rapid urbanization and immigration. The aim of this review is to evaluate and discuss prominent epidemiological findings, deficiencies and possibile future activities related with studies conducted in Turkey about bipolar disorder.. [Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 2014; 6(2.000: 199-209

  20. Aids in Spain and Immigration: Epidemiological Analysis

    ualberto Buela-Casal****; Ángel Castro; María Paz-Bermúdez**

    2009-01-01

    The aim of this work was to analyze the current HIV/AIDS situation in Spain according to Spanish regions. Epidemiological HIV and AIDS Spanish data are analyzed and adjusted by population rates. Prevalence indexes and distribution by gender, age and way of transmission in the Spanish regions are compared. In addition, it is paid special attention to immigrant population as people who can take HIV/AIDS risk behaviors. Results revealed that the Spanish regions with the highest prevalence rates ...

  1. The association between cannabis use and anxiety disorders: Results from a population-based representative sample.

    Feingold, Daniel; Weiser, Mark; Rehm, Jürgen; Lev-Ran, Shaul

    2016-03-01

    The cross-sectional association between cannabis use and anxiety disorders is well documented, yet less is known about the longitudinal association between the two. This study explored the association between cannabis use, cannabis use disorders (CUDs) and anxiety disorders in a 3-year prospective study. Data was drawn from waves 1 and 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Anxiety disorders, including generalized anxiety disorder, social anxiety, panic disorder and specific phobias, were controlled for at baseline. Initiation of cannabis use was defined as any cannabis use by former lifetime abstainers in the time period between baseline and follow-up, CUDs were defined as a diagnosis of cannabis abuse or dependence. Results indicate that cannabis use was not associated with increased incidence of any anxiety disorder (Adjusted Odds Ratio (AOR)=1.12(0.63-0.98)). Though heavy cannabis use was associated with increased incidence of social anxiety in most models, this was not fully retained in the final adjusted model (AOR=1.98(0.99-1.98)). Investigation of the association between baseline CUDs and anxiety disorders at follow-up revealed similar results. Any baseline anxiety disorder was not associated with future initiation of cannabis use (AOR=1.03(0.62-1.69)) or onset of a CUD (AOR=0.68(0.41-1.14)), yet individuals with baseline panic disorder were more prone to initiate cannabis use at follow-up (AOR=2.2(1.15-4.18)), possibly as a means of self-medication. Our findings suggest that cannabis use and CUDs are not associated with increased incidence of most anxiety disorders and inversely, most anxiety disorders are not associated with increased incidence of cannabis use or CUDs. PMID:26775742

  2. Molecular Epidemiology of Rotaviruses

    Nakagomi, Osamu

    2004-01-01

    Molecular epidemiology of rotaviruses emerged a little over 25 years ago as a fascinating branch of science that utilized then cutting-edge technology of RNA polyacrylamide gel electrophoresis. Molecular epidemiology, as I have observed it closely almost since its dawn, is an ever-evolving discipline which has incorporated the advances of the related sciences including molecular evolutionary biology and ecology, while it is firmly and deeply rooted in the edifice of epidemiology of infectious...

  3. Epidemiologi for sundhedspersonale

    En introduktion til fagområdet Epidemiologi. Målgruppen er studerende på mellemlange videregående uddannelser. Bogen består af følgende afsnit: Indledning, beskrivelse, analyse, intervention og anvendt epidemiologi. Herunder: Erhvervsepidemiologi......En introduktion til fagområdet Epidemiologi. Målgruppen er studerende på mellemlange videregående uddannelser. Bogen består af følgende afsnit: Indledning, beskrivelse, analyse, intervention og anvendt epidemiologi. Herunder: Erhvervsepidemiologi...

  4. Making psychiatric epidemiology useful: the contribution of epidemiology to government policy.

    Jenkins, R

    2003-01-01

    This paper aims to discuss the contribution of epidemiology to aspects of public policy that have either a direct influence on mental health and mental disorders, or an indirect effect by influencing environmental factors which influence mental health. Both kinds of public policy will need to be considered by governments wishing to protect, promote, and improve the mental health of their populations. The paper draws on information from both relatively wealthy and low-income countries. The paper defines epidemiology and mental health policy, sets out the range of government policies which may have an impact on mental health, and explores the ways in which epidemiology may contribute to mental health policy in relation to service inputs, processes and outcomes as well as to wider government policies. The paper also examines the advantages and disadvantages of different sources of data. There are a number of reasons to carry out large-scale surveys of psychiatric morbidity. First, effective policy should address the needs of the population, which can best be assessed by the epidemiology and the social and economic causes and consequences of psychiatric morbidity. Secondly, representative information in a defined geographic area can document the use of existing services and can estimate the extent of unmet needs and the services required meeting those needs. Thirdly, valid information on prevalence and associated risk factors of presumed causal importance allow aetiological hypotheses to be generated and tested and models developed for prevention. Finally, by repeating community surveys, it is possible to monitor the health of the population and trends. Epidemiological findings emphasize the importance of mental health policy addressing the key role of primary care, the social context and social consequences of disorder, the importance of addressing services for children, the need to reduce premature mortality from suicide and from physical illness. Epidemiological

  5. Bipolar Disorder in Pregnancy and Postpartum: Principles of Management.

    Khan, Sabrina J; Fersh, Madeleine E; Ernst, Carrie; Klipstein, Kim; Albertini, Elizabeth Streicker; Lusskin, Shari I

    2016-02-01

    Pregnancy and postpartum represent times of increased vulnerability for women with bipolar disorder, yet this condition remains under-diagnosed and under-treated. As 50 % of pregnancies are unplanned, the risks associated with the illness and the potential risks associated with treatment should be considered when a woman of reproductive age first presents for evaluation. This article reviews the epidemiology of perinatal bipolar disorder, screening recommendations, and treatment with pharmacotherapy and electroconvulsive therapy (ECT). An overview of the data in pregnancy and lactation is presented for lithium, lamotrigine, valproic acid, newer antipsychotics, and ECT. General principles of management include close monitoring in pregnancy and postpartum, careful adjustment of the treatment regimen to attenuate the risk of relapse, and avoidance of valproic acid when possible. Thoughtful consideration of these issues will minimize the risks to the mother and baby. PMID:26781551

  6. 西藏自治区四类常见神经精神障碍的流行病学调查%Epidemiological Survey on Neuropsychiatric Disorders in Tibet of China: Neuroses, Alcohol-related Disorders, Mental Retardation and Epilepsy

    刘善明; 苏晓凡; 旺加; 次仁平措; 白玛卓嘎; 次普; 扎桑; 刘协和; 魏赓; 张伟; 向云; 黄晓琦; 杨闯; 黄文军; 谢维爵; 何侠

    2012-01-01

    Objective To investigate the prevalence of four common neuropsychiatric disorders in Tibet, with an aim to providing information support to health planning. Methods The survey was carried out in four regions of Tibet. The sampling strategy was adapted from that of a national psychiatric epidemiological survey in China in 1982 and 1993. The Neurosis Screening Inventory, Screening Inventory for Alcohol Dependence and Related Problems, Child Intelligence Screening Inventory, and a questionnaire for the Detection of Epileptic Seizures were administered to the respondents through face to face interview. Those with a positive response and 10% of those with a negative response were further interviewed with the Structured Clinical Interview for DSM-IV Axis I Disorders (research version) (SCID-1 ). Anxiety disorders and alcohol used disorders were diagnosed according to the American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders (4th edition) (DSM-IV). Hysteria and mental retardation were diagnosed according to the International Classification of Diseases, 10th edition (ICD10), and the Chinese Classification of Mental Disorders, 3rd edition (CCMD-3). Results The point prevalence of neuroses, alcohol-related disorders, mental retardation and epilepsy was 2. 56%, 4. 06%, 0. 28% and 0. 68%, respectively. The lifetime prevalence of neuroses, alcohol-related disorders, mental retardation and epilepsy was 2. 62% , 4. 24% , 0. 28% and 0. 72% , respectively. Conclusion Alcohol-related disorders and neuroses are the two common mental health problems in Tibet. Mental retardation and epilepsy are the two serious neuropsychiatric disorders affecting Tibetan children and adolescence. These disorders should be identified as priorities in the reginonal health planning in Tibet.%目的 了解神经症、酒使用障碍、精神发育迟滞和癫痫这4类常见的神经精神障碍在西藏的流行情况,为政府制订卫生

  7. Repatriation Adjustment: Literature Review

    Gamze Arman

    2009-12-01

    Full Text Available Expatriation is a widely studied area of research in work and organizational psychology. After expatriates accomplish their missions in host countries, they return to their countries and this process is called repatriation. Adjustment constitutes a crucial part in repatriation research. In the present literature review, research about repatriation adjustment was reviewed with the aim of defining the whole picture in this phenomenon. Present research was classified on the basis of a theoretical model of repatriation adjustment. Basic frame consisted of antecedents, adjustment, outcomes as main variables and personal characteristics/coping strategies and organizational strategies as moderating variables.

  8. Theory of adaptive adjustment

    Weihong Huang

    2000-01-01

    Full Text Available Conventional adaptive expectation as a mechanism of stabilizing an unstable economic process is reexamined through a generalization to an adaptive adjustment framework. The generic structures of equilibria that can be stabilized through an adaptive adjustment mechanism are identified. The generalization can be applied to a broad class of discrete economic processes where the variables interested can be adjusted or controlled directly by economic agents such as in cobweb dynamics, Cournot games, Oligopoly markets, tatonnement price adjustment, tariff games, population control through immigration etc.

  9. [Eating disorders in men].

    Bak, Daniel

    2008-01-01

    Despite of being perceived as 'woman's diseases', eating disorders were described among boys and adult men. This article presents epidemiological data on anorexia nervosa, bulimia nervosa and binge eating disorder in men. The clinical presentation of eating disorders in men was described and compared with similar data from the female population. Moreover, a significance of selected risk factors, specifically those referring to men, was discussed. These are: the disturbance of body perception, personality traits and potential association of eating disorders with sexual orientation. Efficacy of different psychotherapy approaches aimed at eating disorders was summarized. Rules governing psychotherapy of men suffering from eating disorders were described. Specific features of eating disorders' aetiology were taken into account together with characteristic difficulties influencing treatment. PMID:19697523

  10. The epidemiology of depression across cultures

    Ronald C. Kessler; Bromet, Evelyn J.

    2013-01-01

    Epidemiological data are reviewed on the prevalence, course, socio-demographic correlates, and societal costs of major depression throughout the world. Major depression is estimated in these surveys to be a commonly-occurring disorder. Although estimates of lifetime prevalence and course vary substantially across countries for reasons that could involve both substantive and methodological processes, the cross-national data are clear in documenting meaningful lifetime prevalence with wide vari...

  11. ADJUSTABLE CHIP HOLDER

    2009-01-01

    An adjustable microchip holder for holding a microchip is provided having a plurality of displaceable interconnection pads for connecting the connection holes of a microchip with one or more external devices or equipment. The adjustable microchip holder can fit different sizes of microchips with ...

  12. Epidemiologic Assessment of 4000 Mental Ill patients (Shiraz /Iran) 2014

    DANESH, Nasrin; GHORBANPOOR, Elahe

    2015-01-01

    Abstract. Summary: Psychiatric disorders are among the most common morbid and stress making problems all around the world.(1) Periodic assessment of rate and effect of diseases ; epidemiologically or economically ; would be helpful for health organizations to plan better for the next generation of drugs or other types of treatment. This is an epidemiologic essay about 4000 out-patients referred to a central mental illness clinic in Shiraz –Iran during a 3 years period (2011-2014) that will sh...

  13. 战后平民幸存者创伤后应激障碍的流行病学研究进展%Advances in epidemiological study of post-traumatic stress disorders among survivors of war trauma

    孔祥毓; 肖立宁; 黄文; 李兆申

    2012-01-01

    创伤后应激障碍(PTSD)是由暴露于生命威胁事件而产生的一种受迫害的感觉,其呈现出的三大特征性症候群包括侵害性症状、逃避症状及易于唤醒症状.关于PTSD流行病学研究的文献很多,但其结果因各自研究对象和评价方法的不同而有所差异.针对难民、迁徙人群及社区人群的研究受到对战争创伤的定义不同、样本选择的不同以及是否进行心理干预等因素的影响而存在较大差异.因此,对战争创伤或精神折磨后平民中PTSD的发病率尚无准确结论.目前针对PTSD的研究存在的不足:一是既往研究分析方法存在差异,不同研究小组间的统计结果也存在差异;现有研究均针对非西方种族及某些特定人群,采用的样本尚存在选择性偏倚.二是绝大多数研究未设置对照组,所得结果缺乏可靠性及通用性.三是战后PTSD的研究应重视国籍及文化背景的影响.PTSD流行病学研究领域还有大量工作要做,建立适合中国人群的简易PTSD筛查和测量工具,开展各类创伤性事件后PTSD发病率及其分布特征的调研,对于PTSD的有效防治具有重要意义.%Post-traumatic stress disorder (PTSD) is a feeling of persecution arising from the exposure to a life-threatening event. PTSD shows three kinds of characteristic syndrome including invasive, evading, and easy-to-wake up syndromes. Numerous literature had been published on the study of the PTSD epidemiology. However, research results varied due to different research subjects and evaluation methods used. A big difference exists among studies on refugees, migrating people, and community population, because these studies are affected by different definition of war trauma, difference in choice of samples, and application of psychological intervention. Therefore, no exact conclusions have been established on the accurate incidence of PTSD in civilians after having endured the trauma of war or mental

  14. Epidemiology & Genomics Research Program

    The Epidemiology and Genomics Research Program, in the National Cancer Institute's Division of Cancer Control and Population Sciences, funds research in human populations to understand the determinants of cancer occurrence and outcomes.

  15. Cancer Epidemiology Cohorts

    Cohort studies are fundamental for epidemiological research by helping researchers better understand the etiology of cancer and provide insights into the key determinants of this disease and its outcomes.

  16. Methodologic frontiers in environmental epidemiology.

    Rothman, K.J.

    1993-01-01

    Environmental epidemiology comprises the epidemiologic study of those environmental factors that are outside the immediate control of the individual. Exposures of interest to environmental epidemiologists include air pollution, water pollution, occupational exposure to physical and chemical agents, as well as psychosocial elements of environmental concern. The main methodologic problem in environmental epidemiology is exposure assessment, a problem that extends through all of epidemiologic re...

  17. Autism Spectrum Disorders

    Rebecca E. Rosenberg

    2011-01-01

    Full Text Available We used a national online registry to examine variation in cumulative prevalence of community diagnosis of psychiatric comorbidity in 4343 children with autism spectrum disorders (ASD. Adjusted multivariate logistic regression models compared influence of individual, family, and geographic factors on cumulative prevalence of parent-reported anxiety disorder, depression, bipolar disorder, and attention deficit/hyperactivity disorder or attention deficit disorder. Adjusted odds of community-assigned lifetime psychiatric comorbidity were significantly higher with each additional year of life, with increasing autism severity, and with Asperger syndrome and pervasive developmental disorder—not otherwise specified compared with autistic disorder. Overall, in this largest study of parent-reported community diagnoses of psychiatric comorbidity, gender, autistic regression, autism severity, and type of ASD all emerged as significant factors correlating with cumulative prevalence. These findings could suggest both underlying trends in actual comorbidity as well as variation in community interpretation and application of comorbid diagnoses in ASD.

  18. Environmental epidemiology: An introduction

    Mohsen Arbabi; Masoud Amiri

    2016-01-01

    Epidemiology is increasingly coping with problems correlated with exposures which may have small relative risks. In fact, many chronic diseases, as the most recent common diseases all over the world, may have unknown etiology but also potentially related to environmental exposures. Environmental epidemiology considers the effect of environmental factors on health. More exposure with increasing number of potential environmental hazards has changed the initial application of environmental epide...

  19. Genetic epidemiology of diabetes

    Permutt, M. Alan; Wasson, Jonathon; Cox, Nancy

    2005-01-01

    Conventional genetic analysis focuses on the genes that account for specific phenotypes, while traditional epidemiology is more concerned with the environmental causes and risk factors related to traits. Genetic epidemiology is an alliance of the 2 fields that focuses on both genetics, including allelic variants in different populations, and environment, in order to explain exactly how genes convey effects in different environmental contexts and to arrive at a more complete comprehension of t...

  20. Premorbid adjustment and previous personality in schizophrenic patients

    José Juan Rodríguez Solano

    2005-12-01

    Full Text Available Psychosocial adjustment and premorbid personality are two factors that are frequently studied in order to elucidate the etiopathogenesis of schizophrenia. Premorbid adjustment alterations and personality disorders (principally those of the schizophrenia spectrum have been considered vulnerability elements or have been linked with the early manifestations of a disease that is still underdeveloped (hypothesis of neurodevelopment. In this paper we review the literature. We also studied the relationship between premorbid adjustment (PAS scale and previous personality disorders (SCID-II in a sample of 40 patients with schizophrenia (DSM-III-R, DSM-IV, CIE-10, and statistically correlated them. The results show that premorbid adjustment correlates with avoidant, schizotypal and schizoid personality disorders: the more personality pathology found, the poorer is the premorbid psychosocial adjustment. Premorbid adjustment positively correlates with histrionic personality traits. The pathological traits of schizotypal and schizoid personalities account for up to 77% of the variance of the total premorbid adjustment in schizophrenic patients. Conclusion: The degrees of premorbid adjustment in schizophrenia are related to the different premorbid personality disorders of schizophrenic patients, which are mainly those most genetically related with schizophrenia, that is, the spectrum of the schizophrenia.

  1. Adjustments and Depression

    Full Text Available ... identity and to find a new balance in relationships. The stages of adjustment can include grieving, taking ... treatment options. Related pages What is a complete vs incomplete injury? What emergency procedures occur following an ...

  2. Adjustments and Depression

    Full Text Available ... thoughts and feelings and is something that takes time. The goal of adjusting is to rebuild one's ... updates about our impact > Get the Reeve newsletter International support > Pages in other languages Made with ♡ in ...

  3. Adjustments and Depression

    Full Text Available ... rebuild one's identity and to find a new balance in relationships. The stages of adjustment can include ... a peer mentor Advocate for change Fundraise with Team Reeve Champions Committee Volunteering About Us Our story ...

  4. Anxiety Disorders and Depression in Older Adults

    K. Hek (Karin)

    2013-01-01

    textabstractAnxiety disorders and depression are common and complex disorders. Despite decades of research, their etiology is largely unknown. Study of the occurrence and determinants, i.e. the epidemiology of anxiety disorders and depression, helps unravel their etiology. This thesis examines the e

  5. Occupational Adjustment of Immigrants

    Zorlu, Aslan

    2011-01-01

    This paper examines the speed of the occupational adjustment of immigrants using Labour Force Surveys 2004 and 2005 from Statistics Netherlands. The analysis provides new evidence that immigrants start with jobs at the lower levels of skill distribution. Their occupational achievement improves significantly with the duration of residence. The extent of this initial disadvantage and the rate of adjustment vary across immigrant groups according to the transferability of skills associated with t...

  6. KVA: Capital Valuation Adjustment

    Andrew Green; Chris Kenyon

    2014-01-01

    Credit (CVA), Debit (DVA) and Funding Valuation Adjustments (FVA) are now familiar valuation adjustments made to the value of a portfolio of derivatives to account for credit risks and funding costs. However, recent changes in the regulatory regime and the increases in regulatory capital requirements has led many banks to include the cost of capital in derivative pricing. This paper formalises the addition of cost of capital by extending the Burgard-Kjaer (2013) semi-replication approach to C...

  7. Antidepressant exposure in pregnancy and risk of autism spectrum disorders

    Sørensen MJ

    2013-11-01

    Full Text Available Merete Juul Sørensen,1 Therese Koops Grønborg,2 Jakob Christensen,3,4 Erik Thorlund Parner,2 Mogens Vestergaard,5,6 Diana Schendel,7 Lars Henning Pedersen8,9 1Regional Centre of Child and Adolescent Psychiatry, Aarhus University Hospital, Risskov, Denmark; 2Department of Public Health, Section of Biostatistics, Aarhus University, Aarhus, Denmark; 3Department of Neurology, Aarhus University Hospital, Aarhus, Denmark; 4Department of Clinical Pharmacology, 5Department of Public Health, Section of General Practice, 6Research unit for General Practice, Aarhus University, Aarhus, Denmark; 7Centers for Disease Control and Prevention, Atlanta, GA, USA; 8Danish Epidemiological Science Centre, Institute of Public Health, 9Department of Obstetrics and Gynecology, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark Background: Both the use of antidepressant medication during pregnancy and the prevalence of autism spectrum disorder have increased during recent years. A causal link has recently been suggested, but the association may be confounded by the underlying indication for antidepressant use. We investigated the association between maternal use of antidepressant medication in pregnancy and autism, controlling for potential confounding factors. Methods: We identified all children born alive in Denmark 1996–2006 (n=668,468 and their parents in the Danish Civil Registration System. We obtained information on the mother's prescriptions filled during pregnancy from the Danish National Prescription Registry, and on diagnoses of autism spectrum disorders in the children and diagnoses of psychiatric disorders in the parents from the Danish Psychiatric Central Register. In a cohort analysis, we estimated hazard ratios of autism spectrum disorders in children exposed to antidepressant medication during pregnancy compared with children who were not exposed, using Cox proportional hazards regression analysis. Furthermore, we estimated the risk

  8. [Antisocial personality disorder].

    Repo-Tiihonen, Eila; Hallikainen, Tero

    2016-01-01

    Antisocial personality disorder (ASP), especially psychopathy as its extreme form, has provoked fear and excitement over thousands of years. Ruthless violence involved in the disorder has inspired scientists, too.The abundance of research results concerning epidemiology, physiology, neuroanatomy, heritability, and treatment interventions has made ASP one of the best documented disorders in psychiatry. Numerous interventions have been tested, but there is no current treatment algorithm. Biological and sociological parameters indicate the importance of early targeted interventions among the high risk children. Otherwise, as adults they cause the greatest harm. The use of medications or psychotherapy for adults needs careful consideration. PMID:26939485

  9. Examining the Relationship between Autistic Traits and College Adjustment

    Trevisan, Dominic; Birmingham, Elina

    2016-01-01

    We examined the relationship between characteristics associated with autism spectrum disorder and college adjustment in a sample of neurotypical college students. Using the Broad Autism Phenotype Questionnaire and the Student Adaptation to College Questionnaire, we found that higher levels of autism spectrum disorder characteristics were…

  10. Mental Disorders

    ... obsessive-compulsive disorder, post-traumatic stress disorder, and phobias Bipolar disorder Depression Mood disorders Personality disorders Psychotic disorders, including schizophrenia There are many causes of mental disorders. Your genes and family history ...

  11. EPIDEMIOLOGY OF SUBSTANCE ABUSE IN INDIA : METHODOLOGICAL ISSUES AND FUTURE PERSPECTIVES

    Basu, Debasish; Mattoo, Surendra K.

    1999-01-01

    Substance abuse is an important medico-social problem. Comprehensive management of substance use disorders is of necessity linked to the study of epidemiology. In India we have a reasonable epidemiological data on substance abuse. However, this data base suffers from a number of methodological lacunae. The present paper discusses these lacunae and makes appropriate recommendations for future generation of epidemiological data on substance abuse in India.

  12. Examining the relationship between autistic traits and college adjustment.

    Trevisan, Dominic; Birmingham, Elina

    2016-08-01

    We examined the relationship between characteristics associated with autism spectrum disorder and college adjustment in a sample of neurotypical college students. Using the Broad Autism Phenotype Questionnaire and the Student Adaptation to College Questionnaire, we found that higher levels of autism spectrum disorder characteristics were associated with poorer adjustment to college. One subscale of the Broad Autism Phenotype Questionnaire, pragmatic language difficulties, explained the most variance in adjustment. In addition, students who met the previously established cut-off scores for possessing the broad autism phenotype scored significantly lower on all Student Adaptation to College Questionnaire subscales. Finally, pragmatic language difficulties mediated the relationship between college major and academic adjustment. These findings underscore the need for future research to examine how pragmatic language difficulties may impede college success in students with autism spectrum disorder and in the typical population. PMID:26471426

  13. National prevalence of respiratory allergic disorders

    Dahl, R; Andersen, PS; Chivato, T; Valovirta, E; De Monchy, J

    2004-01-01

    Background: Many epidemiological studies have assessed the prevalence of respiratory allergic disorders in confined geographical locations. However, no study has yet established nationally prevalence data in a uniform manner representing whole countries and, thus, enabling cross-national comparisons

  14. Ophthalmic epidemiology in Europe

    Delcourt, Cécile; Korobelnik, Jean-François; Buitendijk, Gabriëlle H S;

    2015-01-01

    The European Eye Epidemiology (E3) consortium is a recently formed consortium of 29 groups from 12 European countries. It already comprises 21 population-based studies and 20 other studies (case-control, cases only, randomized trials), providing ophthalmological data on approximately 170,000 Euro......The European Eye Epidemiology (E3) consortium is a recently formed consortium of 29 groups from 12 European countries. It already comprises 21 population-based studies and 20 other studies (case-control, cases only, randomized trials), providing ophthalmological data on approximately 170......,000 European participants. The aim of the consortium is to promote and sustain collaboration and sharing of data and knowledge in the field of ophthalmic epidemiology in Europe, with particular focus on the harmonization of methods for future research, estimation and projection of frequency and impact of...

  15. Adjusting diet with sapropterin in phenylketonuria

    MacDonald, Anita; Ahring, Kirsten; Dokoupil, Katharina;

    2011-01-01

    The usual treatment for phenylketonuria (PKU) is a phenylalanine-restricted diet. Following this diet is challenging, and long-term adherence (and hence metabolic control) is commonly poor. Patients with PKU (usually, but not exclusively, with a relatively mild form of the disorder) who are respo...... relaxation in diet) must also be understood by the patient and carers from the outset. Continuing education and support will be required thereafter, with further adjustment of diet and sapropterin dosage as a young patient grows....

  16. Adjustments and Depression

    Full Text Available ... medical disorder that affects your thoughts, feelings, physical health and behaviors as well as other aspects of ... for you to take good care of your health. Other symptoms include oversleeping, change in weight, loss ...

  17. Nuclear accidents and epidemiology

    A consultation on epidemiology related to the Chernobyl accident was held in Copenhagen in May 1987 as a basis for concerted action. This was followed by a joint IAEA/WHO workshop in Vienna, which reviewed appropriate methodologies for possible long-term effects of radiation following nuclear accidents. The reports of these two meetings are included in this volume, and cover the subjects: 1) Epidemiology related to the Chernobyl nuclear accident. 2) Appropriate methodologies for studying possible long-term effects of radiation on individuals exposed in a nuclear accident. Figs and tabs

  18. Epidemiology of Lung Cancer.

    Mao, Yousheng; Yang, Ding; He, Jie; Krasna, Mark J

    2016-07-01

    Lung cancer has been transformed from a rare disease into a global problem and public health issue. The etiologic factors of lung cancer become more complex along with industrialization, urbanization, and environmental pollution around the world. Currently, the control of lung cancer has attracted worldwide attention. Studies on the epidemiologic characteristics of lung cancer and its relative risk factors have played an important role in the tertiary prevention of lung cancer and in exploring new ways of diagnosis and treatment. This article reviews the current evolution of the epidemiology of lung cancer. PMID:27261907

  19. Long-term sickness absence and disability pension award as consequences of common mental disorders. Epidemiological studies using a population-based health survey and official ill health benefit registries

    Knudsen, Ann Kristin

    2013-01-01

    The common mental disorders anxiety and depression are widespread in the population and will affect 1 in 4 adults at least once during their lifetime. Due to high prevalence of common mental disorders within official benefit statistics, the contribution from these conditions on sickness absence and ill health retirement in the population is increasingly recognised. Sickness absence and ill health retirement rates have increased dramatically across the western world since the 19...

  20. Epidemiological Study to Investigate Potential Interaction Between Physical and Psychosocial Factors at Work that may Increase the Risk of Symptoms of Musculoskeletal Disorder of the Neck and Upper Limb

    Devereux, J. J.; Vlachonikolis, I. G.; Buckle, P. W.

    2002-01-01

    Objectives: To investigate potential interactions between physical and psychosocial risk factors in the workplace that may be associated with symptoms of musculoskeletal disorder of the neck and upper limb. Methods: 891 of 1514 manual handlers, delivery drivers, technicians, customer services computer operators, and general office staff reported on physical and psychosocial working conditions and symptoms of neck and upper limb disorders using a self administered questionnaire (59% return ...

  1. Q Fever: Statistics and Epidemiology

    ... Rates Geography Seasonality Persons at Risk Further Reading Statistics and Epidemiology Annual Cases of Q Fever in ... CDC–INFO Q Fever Symptoms, Diagnosis, and Treatment Statistics and Epidemiology In-Depth Information Prevention Other Ricketssial ...

  2. Sustainable urban regime adjustments

    Quitzau, Maj-Britt; Jensen, Jens Stissing; Elle, Morten;

    2013-01-01

    The endogenous agency that urban governments increasingly portray by making conscious and planned efforts to adjust the regimes they operate within is currently not well captured in transition studies. There is a need to acknowledge the ambiguity of regime enactment at the urban scale. This direc...

  3. Auto Adjusting Astronomical Telescope

    Rohit R. Ghalsasi; Prof. N. D. Dhoot

    2014-01-01

    Astronomical telescope is powerful and basic tool for star or celestial observation. Here we proposed integrated system using Raspberry Pi for auto adjusting astronomical telescope. This integrated circuit helps to control stellar monitoring, stellar targeting, and tracking functions of telescope. Astro compass gives the direction of the celestial objects.

  4. Adjustments and Depression

    Full Text Available ... 7309 ☰ Living with Paralysis Get Support Get Involved Research Events Blog & Forum About Us Donate Living with Paralysis > Newly paralyzed > How do I deal with depression and adjustment to my SCI? How do I deal with depression and ...

  5. Auto Adjusting Astronomical Telescope

    Rohit R. Ghalsasi

    2014-04-01

    Full Text Available Astronomical telescope is powerful and basic tool for star or celestial observation. Here we proposed integrated system using Raspberry Pi for auto adjusting astronomical telescope. This integrated circuit helps to control stellar monitoring, stellar targeting, and tracking functions of telescope. Astro compass gives the direction of the celestial objects.

  6. Phylogenetically resolving epidemiologic linkage

    Romero-Severson, Ethan O.; Bulla, Ingo; Leitner, Thomas

    2016-01-01

    Although the use of phylogenetic trees in epidemiological investigations has become commonplace, their epidemiological interpretation has not been systematically evaluated. Here, we use an HIV-1 within-host coalescent model to probabilistically evaluate transmission histories of two epidemiologically linked hosts. Previous critique of phylogenetic reconstruction has claimed that direction of transmission is difficult to infer, and that the existence of unsampled intermediary links or common sources can never be excluded. The phylogenetic relationship between the HIV populations of epidemiologically linked hosts can be classified into six types of trees, based on cladistic relationships and whether the reconstruction is consistent with the true transmission history or not. We show that the direction of transmission and whether unsampled intermediary links or common sources existed make very different predictions about expected phylogenetic relationships: (i) Direction of transmission can often be established when paraphyly exists, (ii) intermediary links can be excluded when multiple lineages were transmitted, and (iii) when the sampled individuals’ HIV populations both are monophyletic a common source was likely the origin. Inconsistent results, suggesting the wrong transmission direction, were generally rare. In addition, the expected tree topology also depends on the number of transmitted lineages, the sample size, the time of the sample relative to transmission, and how fast the diversity increases after infection. Typically, 20 or more sequences per subject give robust results. We confirm our theoretical evaluations with analyses of real transmission histories and discuss how our findings should aid in interpreting phylogenetic results. PMID:26903617

  7. Molecular epidemiology of ascariasis

    Betson, Martha; Halstead, Fennella; Nejsum, Peter;

      We are using molecular epidemiology techniques to study the population structure of Ascaris obtained from humans and pigs. Worms were obtained from human hosts on Zanzibar and in Uganda, Bangladesh, Guatemala and Nepal and Ascaris from pigs were collected from in Uganda, Tanzania, Denmark...

  8. Inflammatory bowel disease epidemiology

    Burisch, Johan; Munkholm, Pia

    2013-01-01

    The occurrence of inflammatory bowel disease (IBD) is increasing worldwide, yet the reasons remain unknown. New therapeutic approaches have been introduced in medical IBD therapy, but their impact on the natural history of IBD remains uncertain. This review will summarize the recent findings in t...... epidemiology of IBD....

  9. Epidemiology of Cardiovascular Diseases.

    Jenkins, C. David

    1988-01-01

    Reviews epidemiological studies of cardiovascular diseases especially coronary heart disease (CHD), to document their major public health importance, changes in mortality during this century, and international comparisons of trends. Finds major risk factors for CHD are determined in large part by psychosocial and behavioral mechanisms. Asserts…

  10. Changing epidemiology of AIDS.

    Donovan, C. A.; Stratton, E.

    1994-01-01

    It has been 15 years since AIDS made its first appearance in North America, probably longer worldwide. In that time, our knowledge of the epidemiology of AIDS has grown and changed. This review highlights significant aspects of the epidemic with particular emphasis on the evolution of this disease in North America.

  11. Environmental epidemiology: challenges and opportunities.

    Pekkanen, J; Pearce, N.

    2001-01-01

    Epidemiology is struggling increasingly with problems with correlated exposures and small relative risks. As a consequence, some scholars have strongly emphasized molecular epidemiology, whereas others have argued for the importance of the population context and the reintegration of epidemiology into public health. Environmental epidemiology has several unique features that make these debates especially pertinent to it. The very large number of environmental exposures require prioritization, ...

  12. Welcome to Epidemiology and Health

    Choi, Bo Youl

    2009-01-01

    The Korean Society of Epidemiology publishes a scholarly journal titled 'Korean Journal of Epidemiology', which announces and discusses the results of epidemiological studies from the past 30 yr. Since its first publication in 1979, the journal has contributed to the advancement of epidemiology as well as the prevention and control of disease, and the promotion of health in Korea. In 2009, the editorial board has decided to publish the journal in English to contribute internationally, and cha...

  13. Congenital Malformations and Consequential Epidemiology

    Werler, Martha M.

    2015-01-01

    A call for a shift in the discipline of epidemiology, away from those aimed at identifying risk factors and toward those aimed at more directly improving health – so called consequential epidemiology. This call for epidemiologists to engage in solving the biggest public health problems has been heralded for decades by Cates and more recently by Galea [Am J Epidemiol 2013; 178; 1185–94]. In consideration of the consequential epidemiology perspective, the impacts of epidemiologic research of bi...

  14. Mental Disorders

    Mental disorders include a wide range of problems, including Anxiety disorders, including panic disorder, obsessive-compulsive disorder, post- ... disorders, including schizophrenia There are many causes of mental disorders. Your genes and family history may play a ...

  15. Epidemiology applied to health physics

    The technical program of the mid-year meeting of the Health Physics Society, entitled Epidemiology Applied to Health physics, was developed to meet three objectives: (1) give health physicists a deeper understanding of the basics of epidemiological methods and their use in developing standards, regulations, and criteria and in risk assessment; (2) present current reports on recently completed or on-going epidemiology studies; and (3) encourage greater interaction between the health physics and epidemiology disciplines. Included are studies relating methods in epidemiology to radiation protection standards, risk assessment from exposure to bone-seekers, from occupational exposures in mines, mills and nuclear facilities, and from radioactivity in building materials

  16. Credit Valuation Adjustment

    Hoffman, Frederick

    2011-01-01

    Credit risk has become a topical issue since the 2007 Credit Crisis, particularly for its impact on the valuation of OTC derivatives. This becomes critical when the credit risk of entities involved in a contract either as underlying or counterparty become highly correlated as is the case during macroeconomic shocks. It impacts the valuation of such contracts through an additional term, the credit valuation adjustment (CVA). This can become large with such correlation. This thesis outlines the...

  17. Adjustable Autonomy Testbed

    Malin, Jane T.; Schrenkenghost, Debra K.

    2001-01-01

    The Adjustable Autonomy Testbed (AAT) is a simulation-based testbed located in the Intelligent Systems Laboratory in the Automation, Robotics and Simulation Division at NASA Johnson Space Center. The purpose of the testbed is to support evaluation and validation of prototypes of adjustable autonomous agent software for control and fault management for complex systems. The AA T project has developed prototype adjustable autonomous agent software and human interfaces for cooperative fault management. This software builds on current autonomous agent technology by altering the architecture, components and interfaces for effective teamwork between autonomous systems and human experts. Autonomous agents include a planner, flexible executive, low level control and deductive model-based fault isolation. Adjustable autonomy is intended to increase the flexibility and effectiveness of fault management with an autonomous system. The test domain for this work is control of advanced life support systems for habitats for planetary exploration. The CONFIG hybrid discrete event simulation environment provides flexible and dynamically reconfigurable models of the behavior of components and fluids in the life support systems. Both discrete event and continuous (discrete time) simulation are supported, and flows and pressures are computed globally. This provides fast dynamic simulations of interacting hardware systems in closed loops that can be reconfigured during operations scenarios, producing complex cascading effects of operations and failures. Current object-oriented model libraries support modeling of fluid systems, and models have been developed of physico-chemical and biological subsystems for processing advanced life support gases. In FY01, water recovery system models will be developed.

  18. Physicians' adjustment to retirement.

    Virshup, B; Coombs, R H

    1993-01-01

    We address the questions, How do physicians adjust to and enjoy their retirement? What factors contribute to the well-being of retired physicians? A 60-item questionnaire mailed to 238 retired physicians in Los Angeles County with a 41.6% response rate assessed health, standard of living, relationships, activities, emotional difficulties, and general enjoyment. Health often improved after retirement, as did relationships with spouses and children. Standard of living was comfortable or better ...

  19. Adjustments and Depression

    Full Text Available ... Depression, however, is a serious medical disorder that affects your thoughts, feelings, physical health and behaviors as well as other aspects of your life. Depression can cause physical and psychological symptoms. It can worsen pain, make sleep difficult, cause loss of energy, take away your ...

  20. [Enduring pain I. Nosology and epidemiology].

    Vigo, Daniel V; Selle, Valerio; Baldessarini, Ross

    2013-01-01

    Pain disorders are extraordinarily prevalent throughout clinical medicine, and are highly co-morbid with various psychiatric disorders, particularly those including depression or anxiety. Assessment of such patients tends to be based on diagnostic criteria that may not reflect the complexity of the clinical problem and can result in prioritizing somatic aspects of painful syndromes at the expense of psychiatric aspects or, conversely, over-emphasize psychiatric aspects. In the first part of this overview we consider current nosological perspectives and their potential clinical consequences, epidemiological data that underscore the association of comorbid painful and affective or anxious syndromes, and consider the importance of psychiatric assessment and treatment of such patients. The major overlap between pain disorders and psychiatric disorders, as well as the unsatisfactory state of treatments available for chronic pain syndromes, encourage a comprehensive approach to assessing and clinically managing patients with chronic pain. Many programs for pain disorder patients offer narrowly specialized treatment options. To be preferred are multi-disciplinary teams with expertise in internal medicine, neurology, pain management, and rehabilitation, as well as psychology and psychiatry. In the second part of this overview, we propose that psychiatrists can serve a key role in leading comprehensive assessment and management of complex and challenging pain-psychiatric patients who are typically only partially responsive to available treatments. PMID:24312918

  1. Adjustment Criterion and Algorithm in Adjustment Model with Uncertain

    SONG Yingchun

    2015-02-01

    Full Text Available Uncertainty often exists in the process of obtaining measurement data, which affects the reliability of parameter estimation. This paper establishes a new adjustment model in which uncertainty is incorporated into the function model as a parameter. A new adjustment criterion and its iterative algorithm are given based on uncertainty propagation law in the residual error, in which the maximum possible uncertainty is minimized. This paper also analyzes, with examples, the different adjustment criteria and features of optimal solutions about the least-squares adjustment, the uncertainty adjustment and total least-squares adjustment. Existing error theory is extended with new observational data processing method about uncertainty.

  2. Epidemiology and ionizing radiations

    The ionizing radiations have effects on living being. The determinist effects appear since a threshold of absorbed dose of radiation is reached. In return, the stochastic effects of ionizing radiations are these ones whom apparition cannot be described except in terms of probabilities. They are in one hand, cancers and leukemia, on the other hand, lesions of the genome potentially transmissible to the descendants. That is why epidemiology, defined by specialists as the science that studies the frequency and distribution of illness in time and space, the contribution of factors that determine this frequency and this distribution among human populations. This issue gathers and synthesizes the knowledge and examines the difficulties of methodologies. It allows to give its true place to epidemiology. (N.C.)

  3. The prevalence and significance of substance use disorders in bipolar type I and II disorder

    Strakowski Stephen M; Cerullo Michael A

    2007-01-01

    Abstract The aim of this paper is to provide a systematic review of the literature examining the epidemiology, outcome, and treatment of patients with bipolar disorder and co-occurring substance use disorders (SUDs). Articles for this review were initially selected via a comprehensive Medline search and further studies were obtained from the references in these articles. Given the lack of research in this field, all relevant studies except case reports were included. Prior epidemiological res...

  4. Genetic and molecular epidemiology

    John P A Ioannidis

    2007-01-01

    Genetic and molecular epidemiology covers a vast area of research. Given the rapid changes in this field, discussing a research agenda is a precarious and ambitious task. A representative set of high‐priority concepts will be presented here, each of which alone could be the topic of a long series of essays. The wish list includes issues of full transparency and integration of information, dealing efficiently with complex multidimensional biology, juxtaposing the genome and environmental expos...

  5. Prospects for Epigenetic Epidemiology

    Debra L Foley; Craig, Jeffrey M; Morley, Ruth; Olsson, Craig J.; Dwyer, Terence; Smith, Katherine; Saffery, Richard

    2009-01-01

    Epigenetic modification can mediate environmental influences on gene expression and can modulate the disease risk associated with genetic variation. Epigenetic analysis therefore holds substantial promise for identifying mechanisms through which genetic and environmental factors jointly contribute to disease risk. The spatial and temporal variance in epigenetic profile is of particular relevance for developmental epidemiology and the study of aging, including the variable age at onset for man...

  6. Epidemiology of ovarian malignancies

    Akanksha Sood

    2016-01-01

    Conclusions: The epidemiology and presentation of ovarian tumours has remained unchanged since last 3 decades. Nulliparity is not as significant a factor in the aetiology of ovarian malignancy however contraception leading to anovulatory cycles (OC pills may have a protective role. Infertility can be suggested as a risk factor but the treatment for infertility and its role in oncogenesis remains controversial. [Int J Reprod Contracept Obstet Gynecol 2016; 5(1.000: 186-193

  7. Causation in epidemiology

    Parascandola, M; Weed, D

    2001-01-01

    Causation is an essential concept in epidemiology, yet there is no single, clearly articulated definition for the discipline. From a systematic review of the literature, five categories can be delineated: production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic. Strengths and weaknesses of these categories are examined in terms of proposed characteristics of a useful scientific definition of causation: it must be specific enough to distinguish causation fr...

  8. Environmental epidemiology: risk assessment

    Prentice, R.L.; Whittemore, A.S. (eds.)

    1982-01-01

    Papers presented at the symposium are in the disciplines of biometry, environmental medicine, epidemiology, mathematics, and statistics. Attention is given to assessing risk due to environmental agents, particularly those known to be carcinogenic; both the complex medical issues involved and the mathematical and statistical methodologies used in analysis are presented. Separate abstracts have been prepared for 15 papers for inclusion in the Energy Data Base. (RJC)

  9. Epidemiology of dentin hypersensitivity

    Splieth, Christian H.; Tachou, Aikaterini

    2012-01-01

    Objective In contrast to the well-established caries epidemiology, data on dentin hypersensitivity seem to be scarce and contradictory. This review evaluates the available literature on dentin hypersensitivity and assesses its prevalence, distribution, and potential changes. Materials and methods The systematic search was performed to identify and select relevant publications with several key words in electronic databases. In addition, the articles’ bibliographies were consulted. Results Prev...

  10. Epidemiology of Lyme Disease

    White, Dennis J

    1991-01-01

    Investigation of the epidemiology of Lyme disease depends upon information generated from several sources. Human disease surveillance can be conducted by both passive and active means involving physicians, public health agencies and laboratories. Passive and active tick surveillance programs can document the extent of tick-borne activity, identify the geographic range of potential vector species, and determine the relative risk of exposure to Lyme disease in specific areas. Standardized labor...

  11. Epidemiology of Lyme borreliosis

    Hubálek, Zdeněk

    Basel : Karger, 2009 - (Lipsker, D.; Jaulhac, B., B.), s. 31-50 ISBN 978-3-8055-9114-0. - (Current Problems in Dermatology. 37) Grant ostatní: 6th Framework Programme(XE) GOCE-2003-010284 EDEN Institutional research plan: CEZ:AV0Z60930519 Keywords : Borrelia burgdorferi sensu lato * infectious disease s * natural focality of disease s * incidence rates * environmental effects Subject RIV: FN - Epidemiology, Contagious Disease s ; Clinical Immunology

  12. Epidemiology of Parkinson's disease

    Liu, Shu-Ying; Chan, Piu

    2016-01-01

    Parkinson's disease (PD) is a common neurodegenerative disease in the aged populations, which is characterized by resting tremor, rigidity, bradykinesia and abnormal gait, accompanied by a variety of non-motor symptoms (NMS). The prevalence and incidence of PD rise sharply with the increase of age. In the advent of global aging, the rapid growing of elderly populations results in a rising number of PD patients, especially in China. A correct understanding of the epidemiology of PD helps...

  13. Epidemiology of psoriatic arthritis

    C. Salvarani

    2012-06-01

    Full Text Available Epidemiological studies on psoriatic arthritis have long been hampered by the absence of widely accepted classification criteria. The development of the CASPAR (ClASsification criteria for Psoriatic ARthritis criteria has recently provided the framework for conducting epidemiological studies in psoriatic arthritis using uniform recruitment criteria. However, so far, only a minority of studies have adopted such criteria. In addition to the lack of shared classification criteria, differences in study settings, designs, and ascertainment methods have contributed to yield substantial disparities in the estimates of the incidence (from 3,02 to 23,1 cases per 100,000 people and prevalence (from 49,1 to 420 cases per 100,000 people of psoriatic arthritis around the globe. Overall, the available data suggests that the prevalence of psoriasis in the general population is approximately 2-3%, with about a third of patients with psoriasis having arthritis. Therefore, psoriatic arthritis may affect 0,3- 1,0% of the population, a frequency not dissimilar from that of rheumatoid arthritis. Future epidemiological studies should be carried out in larger numbers of patients diagnosed using consistent criteria.

  14. [Occupational epidemiology in Italy].

    Assennato, G; Bisceglia, L

    2003-01-01

    The development of Occupational Epidemiology in Italy is closely correlated with the political and social awareness of the needs of preventive strategies in the workplace. In the late '60s the Trade Unions supported a model of intervention based on the involvement of the so-called "Homogeneous group of workers" in the validation of the preventive measures taken on the workplace. In spite of the shortcomings of the model, it was extremely effective resulting in enhanced perception of the priority of preventive strategies and in the formation within the National Health Service of the Occupational Health Services. In Italy over the period 1973-2002 there has been an impressive trend of research in field of occupational epidemiology (a search on Medline shows an increasing trend over the years and, in terms of international comparison, higher figures than in Germany, France and Spain). Occupational Epidemiology is now present in the activities of the local Occupational Health Services and in the teaching activities of the Medical Schools throughout the country. PMID:14582235

  15. 浦东新区社区老人焦虑障碍流行病学特征调查分析%Epidemiological characteristics of anxiety disorders in elderly in Pudong New District, Shanghai: A community-based study

    瞿正万; 闵婕; 刘旻佳; 陆伟; 秦虹云; 裴瑜; 王红; 杨振东; 江琦; 袁杰; 秦金; 唐强; 卢瑛; 孙一颖; 奚玥

    2011-01-01

    目的 开展老年焦虑障碍流行病学调查,观察其患病率及其易感因素,为防治疾病提供重要依据.方法 随机抽样调查浦东新区43 个村(居)委会在册常住3311 例老人,应用美国精神障碍诊断与统计手册第4 版(DSM-Ⅳ)轴Ⅰ障碍定式临床检查患者版"SCID-Ⅰ/P"诊断工具进行调查.结果 焦虑障碍时点患病率为2.57%(85/3311),其中广泛性焦虑最高(1.27%),且城市(1.54%)高于农村(0.72%).男性为2.51%,女性为2.59%.该疾病与家庭居住条件差、患躯体疾病、家庭经济困难及遭遇明显精神压力等易感因素关系密切.患者的诊治率很低(9.41%).结论 老年焦虑障碍患病有逐年增高趋势,预防易感因素有利于降低其发生发展.%Objective To observe the prevalence and risk factors of anxiety disorders in elderly in community setting to provide countermeasures for this disorder. Methods In Pudong New Area, 3311 elderly residents were randomly selected in 43 villages ( neighhorhood ) , it was applied with United States Diagnostic and Statistical Manual of Mental Disorders 4th edition ( DSMlV ) Axis Ⅰ Disorders-style version of the clinical examination of patients ( SCID- I /P) diagnostic tool for investigation . Results The point prevalence of anxiety disorders was 2. 57% ( 85 cases) , generalized anxiety was the highest ( 1. 27% ) and was higher( 1. 54% )in urban than rural ( 0. 72% ). It was 2. 51% of male, 2. 59% of women. The disease was associated with a poor family living condition. suffering from physical illness , family financial difficulties and suffered significant mental stress . The patients to be diagnosed and treated were very low (9. 41% ) . Conclusions Prevalence of anxiety disorders are increasing year by year in elderly,the prevention of the risk factors helps to reduce the occurrence and development of the disease.

  16. Vitiligo: Compendium of clinico-epidemiological features

    Sehgal Virendra

    2007-01-01

    Full Text Available Vitiligo, an autoimmune disorder characterized by localized and / or generalized depigmentation of the skin and / or mucous membranes, is a well-recognized entity. The imperatives of its epidemiology both in rural India and in global reckoning have been highlighted frequently. Its morphology is striking and is characterized by asymptomatic ivory / chalky white macule(s that may be frequently surrounded by a prominent pigmented border, the ′trichrome vitiligo′. However vitiligo may have morphological variations in the form of: trichrome, quadri-chrome, penta-chrome, blue and inflammatory vitiligo. Its current topographical classification into segmental, zosteriform and nonsegmental, areata, vulgaris, acrofacialis and mucosal represent its well acclaimed presentations. Its adult and childhood onset is well appreciated as also its presentation in males and females. Occasionally, it may be possible to identify triggering factors. Vitiligo may be associated with cutaneous, ocular and systemic disorders, the details of which are discussed in this article.

  17. Bipolar spectrum disorders. New perspectives.

    Piver, Andre; Yatham, Lakshmi N.; Raymond W. Lam

    2002-01-01

    OBJECTIVE: To review new perspectives on diagnosis, clinical features, epidemiology, and treatment of bipolar II and related disorders. QUALITY OF EVIDENCE: Articles were identified by searching MEDLINE and ClinPSYCH from January 1994 to August 2001 using the key words bipolar disorder, type II or 2; hypomania; spectrum; or variants. Reference lists from articles were reviewed. Overall, the quality of evidence was not high; we found no randomized controlled trials that specifically addressed ...

  18. Jordan Adjusted Human Development

    Ababsa, Myriam

    2014-01-01

    Jordan Human Development Index (HDI) and Adjusted Human Development Index (IHDI) In 1990, the United Nations Development Programme designed a Human Development Index composed of life expectancy at birth, level of education and gross domestic product (GDP) per capita. In 2011, the UNDP ranked Jordan 95th out of 187 countries with a human development index of 0.698, up from 0.591 in 1990, making it the leading medium-range country for human development (fig. VIII.1). In 2010, the inequality adj...

  19. Chronic complex dissociative disorders and borderline personality disorder: disorders of emotion dysregulation?

    Brand, Bethany L; Lanius, Ruth A

    2014-01-01

    Emotion dysregulation is a core feature of chronic complex dissociative disorders (DD), as it is for borderline personality disorder (BPD). Chronic complex DD include dissociative identity disorder (DID) and the most common form of dissociative disorder not otherwise specified (DDNOS, type 1), now known as Other Specified Dissociative Disorders (OSDD, type 1). BPD is a common comorbid disorder with DD, although preliminary research indicates the disorders have some distinguishing features as well as considerable overlap. This article focuses on the epidemiology, clinical presentation, psychological profile, treatment, and neurobiology of chronic complex DD with emphasis placed on the role of emotion dysregulation in each of these areas. Trauma experts conceptualize borderline symptoms as often being trauma based, as are chronic complex DD. We review the preliminary research that compares DD to BPD in the hopes that this will stimulate additional comparative research. PMID:26401297

  20. Epidemiology and genetics of hypertrophic cardiomyopathy

    Tanjore Reena

    2006-01-01

    Full Text Available Background: Hypertrophic cardiomyopathy (HCM is a heart muscle disorder and is known to be inherited as an autosomal dominant trait. Mutations in several sarcomeric, cytoskeletal and mitochondrial genes have been reported in HCM. Though many cases of HCM are being identified, there is limited data regarding the epidemiology and genetics of HCM in India. Aim: Therefore the present study is envisaged at identifying the epidemiological variables in HCM and fitting a probability model assuming dominant mode of inheritance in HCM, which may in turn shed light on the heterogeneity of this complex disorder. Materials AND Methods: The 127 HCM cases were divided into subtypes based on pattern of hypertrophy. Chi square analysis, odds ratio, probability, relative frequency, penetrance and heritability estimates were calculated apart from epidemiological variables. Results: The HCM subtypes revealed the heterogeneous nature of the condition suggesting that the genes/mutations involved in their pathogenesis are different and this is supported by distinctive differences observed in their probability, heritability and penetrance estimates apart from epidemiological variables. An increased male preponderance was observed with the sex ratio being 3.7:1. The age at onset was found to be more than a decade early in familial cases (30 ± 10 yrs compared to non familial cases (44 ± 14 yrs. Chi square analysis revealed obstructive HCM to be following autosomal dominant mode of inheritance where as non-obstructive HCM was significantly deviating. The level of deviation was significantly high for the middle onset group compared to early and late onset groups, therefore this group may be considered as an admixture wherein genes/gene modifiers and environmental variables may be contributing to the heterogeneity and this is further supported by odds ratio. Conclusions: The study thus brings out the complexity of HCM and suggests that modes of inheritance other than

  1. Continuously adjustable Pulfrich spectacles

    Jacobs, Ken; Karpf, Ron

    2011-03-01

    A number of Pulfrich 3-D movies and TV shows have been produced, but the standard implementation has inherent drawbacks. The movie and TV industries have correctly concluded that the standard Pulfrich 3-D implementation is not a useful 3-D technique. Continuously Adjustable Pulfrich Spectacles (CAPS) is a new implementation of the Pulfrich effect that allows any scene containing movement in a standard 2-D movie, which are most scenes, to be optionally viewed in 3-D using inexpensive viewing specs. Recent scientific results in the fields of human perception, optoelectronics, video compression and video format conversion are translated into a new implementation of Pulfrich 3- D. CAPS uses these results to continuously adjust to the movie so that the viewing spectacles always conform to the optical density that optimizes the Pulfrich stereoscopic illusion. CAPS instantly provides 3-D immersion to any moving scene in any 2-D movie. Without the glasses, the movie will appear as a normal 2-D image. CAPS work on any viewing device, and with any distribution medium. CAPS is appropriate for viewing Internet streamed movies in 3-D.

  2. Treatment for illegal drug use disorders: the role of comorbid mood and anxiety disorders.

    Melchior, Maria; Prokofyeva, Elena; Younès, Nadia; Surkan, Pamela; Martins, Silvia

    2014-01-01

    BACKGROUND: Our aim was to examine whether comorbid mood and anxiety disorders influence patterns of treatment or the perceived unmet need for treatment among those not receiving treatment for illegal drug use disorders. METHODS: Data came from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC, 2001-2002 and 2004-2005, n = 34,653). Lifetime DSM-IV illegal drug use disorder (abuse and dependence), as well as comorbid mood (major depression, dysthymia, manic disorder, ...

  3. Diagnosis and treatment of impulse control disorders in patients with movement disorders

    Mestre, Tiago A; Strafella, Antonio P.; Thomsen, Teri; Voon, Valerie; Miyasaki, Janis

    2013-01-01

    Impulse control disorders are a psychiatric condition characterized by the failure to resist an impulsive act or behavior that may be harmful to self or others. In movement disorders, impulse control disorders are associated with dopaminergic treatment, notably dopamine agonists (DAs). Impulse control disorders have been studied extensively in Parkinson’s disease, but are also recognized in restless leg syndrome and atypical Parkinsonian syndromes. Epidemiological studies suggest younger age,...

  4. The Design of Fiscal Adjustments

    Alesina, Alberto Francesco; Ardagna, Silvia

    2013-01-01

    This paper offers three results. First, in line with the previous literature, we confirm that fiscal adjustments based mostly on the spending side are less likely to be reversed. Second, spending based fiscal adjustments have caused smaller recessions than tax based fiscal adjustments. Finally, certain combinations of policies have made it possible for spending based fiscal adjustments to be associated with growth in the economy even on impact rather than with a recession. Thus, expansionary ...

  5. Mendelian randomization in nutritional epidemiology

    Qi, Lu

    2009-01-01

    Nutritional epidemiology aims to identify dietary and lifestyle causes for human diseases. Causality inference in nutritional epidemiology is largely based on evidence from studies of observational design, and may be distorted by unmeasured or residual confounding and reverse causation. Mendelian randomization is a recently developed methodology that combines genetic and classical epidemiological analysis to infer causality for environmental exposures, based on the principle of Mendel’s law o...

  6. Technical Document for Price Adjustment

    Zheng Tian; Mulugeta Kahsai; Randall Jackson

    2014-01-01

    This document presents the basis for the price adjustment mechanisms in a time series IO model. The essentials of the price adjustment and price change propagation algorithms are presented, along with a matrix permutation algorithm that facilitates the implementation of the price adjustment mechanism. The Matlab function is provided.

  7. Epidemiological Perspectives of Diabetes.

    Tao, Ziqi; Shi, Aimin; Zhao, Jing

    2015-09-01

    The global statistics of diabetes mellitus in year 2013 indicated, about 382 million people had this disease worldwide, with type 2 diabetes making up about 90 % of the cases. This is equal to 8.3 % of the adult population with equal rates in both women and men. In year 2012 and 2013 diabetes resulted in mortality of 1.5-5.1 million people per year, making it the 8th leading cause of death in the world. It is predicted that by year 2035 about 592 million people will die of diabetes. The economic cost of diabetes seems to have increased worldwide. An average age of onset of diabetes is 42.5 years and could be due to consumption of high sugar and high-calorie diet, low physical activity, genetic susceptibility, and lifestyle. Approximately 8 % children and about 26 % young adults have diabetes mellitus in the world. The results of epidemiological study of type 1 diabetes mellitus (T1D) are presented by demographic, geographic, biologic, cultural, and other factors in human populations. The prevalence of T1D has been increased by 2-5 % worldwide and its prevalence is approximately one in 300 in US by 18 years of age. The epidemiological studies are important to study the role, causes, clinical care, prevention, and treatment of type1 diabetes in pregnant women and their children before and after birth. In this article, causes, diagnosis, symptoms, treatment and medications, and epidemiology of diabetes will be described. PMID:25711186

  8. The Schisto Track: A System for Gathering and Monitoring Epidemiological Surveys by Connecting Geographical Information Systems in Real Time

    Leal Neto, Onicio B; Albuquerque, Cesar M; Albuquerque, Jones O; Barbosa, Constança S.

    2014-01-01

    Background Using the Android platform as a notification instrument for diseases and disorders forms a new alternative for computerization of epidemiological studies. Objective The objective of our study was to construct a tool for gathering epidemiological data on schistosomiasis using the Android platform. Methods The developed application (app), named the Schisto Track, is a tool for data capture and analysis that was designed to meet the needs of a traditional epidemiological survey. An in...

  9. Metric adjusted skew information

    Hansen, Frank

    2008-01-01

    We extend the concept of Wigner-Yanase-Dyson skew information to something we call "metric adjusted skew information" (of a state with respect to a conserved observable). This "skew information" is intended to be a non-negative quantity bounded by the variance (of an observable in a state) that...... vanishes for observables commuting with the state. We show that the skew information is a convex function on the manifold of states. It also satisfies other requirements, proposed by Wigner and Yanase, for an effective measure-of-information content of a state relative to a conserved observable. We...... establish a connection between the geometrical formulation of quantum statistics as proposed by Chentsov and Morozova and measures of quantum information as introduced by Wigner and Yanase and extended in this article. We show that the set of normalized Morozova-Chentsov functions describing the possible...

  10. Adjusting to the Emergent

    Revsbæk, Line

    In her doctoral thesis Line Revsbaek explores newcomer innovation related to organizational entry processes in a changing organization. She introduces process philosophy and complexity theory to research on organizational socialization and newcomer innovation. The study challenges assumptions...... in standardized induction programs where newcomers are cast in roles as insecure novices needing to be “taught the ropes” of the organizational culture. Linked with this, it is suggested that the prevailing dichotomy of ‘newcomer assimilation’ versus ‘organizational accommodation’ is replaced with a notion...... of ‘adjusting to the emergent’. Newcomer innovation is portrayed as carrying a variety of possible significations, such as unintentional innovation effects of newcomer’s proactive self-socializing behavior; an inspirational basis for designing innovation-generating employee induction; ‘resonant instances...

  11. A Review of Body Dysmorphic Disorder and Its Presentation in Different Clinical Settings

    Mufaddel, Amir; Osman, Ossama T.; Almugaddam, Fadwa; Jafferany, Mohammad

    2013-01-01

    Objective: Body dysmorphic disorder (BDD) is a relatively common psychiatric disorder characterized by preoccupations with perceived defects in physical appearance. This review aimed to explore epidemiology, clinical features, comorbidities, and treatment options for BDD in different clinical settings.

  12. Transtorno dismórfico corporal em dermatologia: diagnóstico, epidemiologia e aspectos clínicos Body dysmorphic disorder in dermatology: diagnosis, epidemiology and clinical aspects

    Luciana Archetti Conrado

    2009-12-01

    Full Text Available São cada vez mais frequentes as queixas cosméticas, uma vez que objetivam a perfeição das formas do corpo e da pele. Os dermatologistas são consultados para avaliar e tratar essas queixas. Sendo assim, é importante conhecer o Transtorno Dismórfico Corporal, inicialmente chamado de "dismorfofobia", pouco estudado até recentemente. Esse transtorno é relativamente comum, por vezes, incapacitante, e envolve uma percepção distorcida da imagem corporal, caracterizada pela preocupação exagerada com um defeito imaginário na aparência ou com um mínimo defeito corporal presente. A maioria dos pacientes apresenta algum grau de prejuízo no funcionamento social e ocupacional, e como resultado de suas queixas obsessivas com a aparência, podem desenvolver comportamentos compulsivos, e, em casos mais graves, há risco de suicídio. O nível de crença é prejudicado, visto que não reconhecem o seu defeito como mínimo ou inexistente e, frequentemente, procuram tratamentos cosméticos para um transtorno psíquico. A prevalência do transtorno, na população geral, é de 1 a 2% e, em pacientes dermatológicos e de cirurgia cosmética, de 2,9 a 16%. Considerando a alta prevalência do Transtorno Dismórfico Corporal, em pacientes dermatológicos, e que os tratamentos cosméticos raramente melhoram seus sintomas, o treinamento dos profissionais para a investigação sistemática, diagnóstico e encaminhamento para tratamento psiquiátrico é fundamental.Cosmetic concerns are becoming increasingly common in view of the obsession with the perfect body and skin. Dermatologists are often seen to evaluate and treat these conditions. Therefore, it is important to acknowledge the existence of Body Dysmorphic Disorder, also known as dysmorphophobia. Despite being relatively common, this disorder has not been well researched. Sometimes causing impairment, the disease involves a distorted body image perception characterized by excessive preoccupation with

  13. Epidemiology Abuse: Epidemiological and Psychosocial Models of Drug Abuse

    Jacobs, Phillip E.

    1976-01-01

    In a paper presented at the National Drug Abuse Conference April 4-7, 1975, New Orleans, Louisiana, epidemiological and psychosocial approaches to drug abuse are discussed. An approach reflecting an appreciation of the psychological/social/political realities involved in addiction as well as a grounding in epidemiological principles and data is…

  14. Molecular Epidemiology and its Role in Translational Medicine

    Yeong Yeh Lee

    2016-01-01

    The primary deifnition of translational medicine is to develop new clinical therapeutic methods for the diagnosis, treatment and prognosis of diseases by the therapeutic mechanism and new pathological cognition obtained in laboratory. Since the 21st century, most developed countries worldwide have made great adjustment in the strategies of translational medicine, but so far, only a few basic research results have been successfully translated into clinical practice. Research of translational medicine requires the team work of interdisciplinary groups, including medical experts, molecular biologists, and epidemiologists. With the rapid development of biological techniques and extensive application of molecular biology, epidemiology has become a real interdisciplinary discipline from conventional population survey, and stepped into genetic and molecular era, an era of molecular epidemiology. Molecular epidemiology not only provides research ifndings to translational medicine, but also bridges between basic science and medical research, so as to improve the effective translation of basic scientiifc results. This article, focusing on molecular epidemiology and translational medicine, mainly summarized the history and current status of translational medicine and emphatically interpreted the importance of molecular epidemiology to translational medicine.

  15. Clinical Epidemiology Of Stroke

    Nagaraja D

    2005-01-01

    Full Text Available Stroke is a huge public health problem because of its high morbidity and disability. The epidemiology of stroke is of relevance to construct practical paradigms to tackle this major health issue in the community. Recent data have shown that about 72-86% of strokes are ischemic, 9-18% are due to hemorrhage (intracerebral of subarachnoid and the rest are undefined. The risk factors for stroke are multiple and combined. At present, stroke is no more considered as unavoidable and untreatable. It is an emergency and specialized units and teams improve outcome and lower costs. Death related to stroke is declining in many countries and in both sexes. This decrease in multifactorial. The detection and more effective treatment of hypertension may play an important factor, as well as the improved medical care and improvement in diagnostic procedures. While stroke incidence appears stable and stroke mortality is slowly declining, the absolute magnitude of stroke is likely to grow over the next 30 years. as the population ages, the absolute number of stroke victims and demands on healthcare and other support systems is likely to increase substantially in the future. Keeping this in perspective, this chapter shall focus on the epidemiology of stroke in the world and in Indian, in particular.

  16. Sibling number and prevalence of allergic disorders in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study

    Arakawa Masashi

    2011-07-01

    Full Text Available Abstract Background Although an inverse relationship between number of siblings and likelihood of allergic disorders has been shown in many epidemiological studies, the biological mechanism underlying this phenomenon has not yet been identified. There is no epidemiological research regarding the sibling effect on allergic disorders in Japanese adults. The current cross-sectional study examined the relationship between number of siblings and prevalence of allergic disorders among adult women in Japan. Methods Subjects were 1745 pregnant women. This study was based on questionnaire data. The definitions of wheeze and asthma were based on criteria from the European Community Respiratory Health Survey whereas those of eczema and rhinoconjunctivitis were based on criteria from the International Study of Asthma and Allergies in Childhood. Adjustment was made for age, region of residence, pack-years of smoking, secondhand smoke exposure at home and at work, family history of asthma, atopic eczema, and allergic rhinitis, household income, and education. Results The prevalence values of wheeze, asthma, eczema, and rhinoconjunctivitis in the past 12 months were 10.4%, 5.5%, 13.0%, and 25.9%, respectively. A significant inverse exposure-response relationship was observed between the number of older siblings and rhinoconjunctivitis, but not wheeze, asthma, or eczema (P for trend = 0.03; however, the adjusted odds ratio (OR for having 2 or more older siblings was not significant although the adjusted OR for having 1 older sibling was statistically significant (adjusted OR = 0.71 [95% CI: 0.56-0.91]. Number of total siblings and number of younger siblings were not related to wheeze, asthma, eczema, or rhinoconjunctivitis. Conclusions This study found a significant inverse relationship between the number of older siblings and the prevalence of rhinoconjunctivitis among pregnant Japanese women. Our findings are likely to support the intrauterine programming

  17. Dealing with the exposure variable in occupational and environmental epidemiology

    Axelson, O.

    1985-01-01

    Whereas the outcome variable in epidemiologic research is usually well-defined, the exposure is more diffuse, complex and variable, involving components of both intensity and duration. Usually, the time integral of the intensity has been used as a measure of exposure, e.g. working level months, fibre-years, etc. Toxicological models have suggested, however, that greater importance should be accorded to early exposure in cancer epidemiology, while the recent exposure may be more important as regards the development of some other types of disorders. A simplified approach in cancer epidemiology would be to consider the exposure within a time-window or otherwise allow for induction-latency time. For the practical assessment of exposure, so-called job exposure matrices might be of value, especially if recall bias is suspected, but on the other hand, there is rather little objective indication in the literature that serious recall bias is a major problem in case-referent studies.

  18. TMJ disorders

    TMD; Temporomandibular joint disorders; Temporomandibular muscle disorders ... vessels, and nerves Teeth For many people with temporomandibular joint disorders, the cause is unknown. Some causes given for ...

  19. Phonological disorder

    Articulation disorder; Developmental articulation disorder; Speech distortion; Sound distortion ... Children should be examined for disorders such as: Cognitive problems (such as intellectual disability ) Hearing impairment Neurological ...

  20. A Review of Bipolar Disorder in Adults

    Hilty, Donald M; Leamon, Martin H.; Lim, Russell F.; Kelly, Rosemary H.; Hales, Robert E.

    2006-01-01

    Objective: This article reviews the epidemiology, etiology, assessment, and management of bipolar disorder. Special attention is paid to factors that complicate treatment, including nonadherence, comorbid disorders, mixed mania, and depression. Methods: A Medline search was conducted from January of 1990 through December of 2005 using key terms of bipolar disorder, diagnosis, and treatment. Papers selected for further review included those published in English in peer-reviewed journals, with ...

  1. Immigration and Mental Disorders among Asian Americans

    Takeuchi, David T.; Zane, Nolan; Hong, Seunghye; Chae, David H.; Gong, Fang; Gee, Gilbert C.; Walton, Emily; Sue, Stanley; Alegria, Margarita

    2007-01-01

    Objectives. We examined lifetime and 12-month rates of any depressive, anxiety, and substance abuse disorders in a national sample of Asian Americans. We focused on factors related to nativity and immigration as possible correlates of mental disorders. Methods. Data were derived from the National Latino and Asian American Study, the first national epidemiological survey of Asian Americans in the United States. Results. The relationships between immigration-related factors and mental disorders...

  2. Clinical Treatment of Obsessive Compulsive Disorder

    Pittenger, Christopher; Kelmendi, Ben; Bloch, Michael; Krystal, John H.; Coric, Vladimir

    2005-01-01

    Obsessive compulsive disorder (OCD) was once thought to be extremely rare, but recent epidemiological studies have shown it to be the fourth most common psychiatric disorder (after substance abuse, specific phobias, and major depression). OCD is often a chronic disorder that produces significant morbidity when not properly diagnosed and treated. The mainstay of treatment includes cognitive behavioral therapy and medication management. The use of clomipramine in the 1960s and then the introduc...

  3. Epidemiology of asthma in India.

    Paramesh, H

    2002-04-01

    Allergic respiratory disorders, in particular asthma are increasing in prevalence, which is a global phenomenon. Even though genetic predisposition is one of the factors in children for the increased prevalence - urbanisation, air pollution and environmental tobacco smoke contribute more significantly. Our hospital based study on 20,000 children under the age of 18 years from 1979,1984,1989,1994 and 1999 in the city of Bangalore showed a prevalence of 9%,10.5%,18.5%, 24.5% and 29.5% respectively. The increased prevalence correlated well with demographic changes of the city. Further to the hospital study, a school survey in 12 schools on 6550 children in the age group of 6 to 15 years was undertaken for prevalence of asthma and children were categorized into three groups depending upon the geographical situation of the school in relation to vehicular traffic and the socioeconomic group of children. Group I-Children from schools of heavy traffic area showed prevalence of 19.34%, Group II-Children from heavy traffic region and low socioeconomic population had 31.14% and Group III-Children from low traffic area school had 11.15% respectively. (P: I & II; II & III <0.001). A continuation of study in rural areas showed 5.7% in children of 6-15 years. The persistent asthma also showed an increase from 20% to 27.5% and persistent severe asthma 4% to 6.5% between 1994-99. Various epidemiological spectra of asthma in children are discussed here. PMID:12019551

  4. Epidemiological Characteristics of Hospitalized Patients with Mental Disor-ders and Related Risk Factors%精神障碍住院患者的流行病学特征及相关危险因素分析

    叶小英; 杨颖佳; 顾雯; 王秋玲; 孔志; 李敏智

    2014-01-01

    目的:探讨精神障碍住院患者的流行病学特征及相关危险因素。方法选取该院自2010年12月-2013年12月以来收治的392例精神障碍住院患者的临床资料进行回顾性分析,自行设计调查问卷,采用软件SPSS20.0对调查数据进行统计分析。结果4种精神障碍住院患者在性别、年龄、职业、婚姻状况、居住地、受教育程度及经济状况上差异有统计学意义(χ2=94.63,P0.05);在既往病史及病程上差异有统计学意义(χ2=86.362,P0.05); the differences in the medical history and duration were statistically significant (χ2=86.362, P<0.05). Conclusion The in-cidence of different kinds of mental disorders has a certain relationship with gender, age, education, occupation, economic condi-tions and so on. Different measures should be taken to treat and prevent different kinds of mental disorders, so as to reduce the oc-currence and development of the disease and improve the quality of life of the patients.

  5. 成人注意力缺陷/多动障碍的流行病学研究和药物治疗进展%Epidemiology and Pharmacotherapy of Adult Attention Deifcit/Hyperactivity Disorder:Current Status

    刘治军

    2012-01-01

    注意力缺陷/多动障碍(attention deficit/hyperactivity disorder,ADHD)是儿童常见的神经发育异常疾病,大多数儿童期ADHD将持续带入到成人期。2012年由美国精神病学协会颁布的DSM-5首次给出了成人ADHD的诊断,规范了成人ADHD的治疗。目前主要的治疗药物包括哌甲酯、苯丙胺类神经兴奋剂类、托莫西汀、安非他酮和三环类抗抑郁药等非兴奋剂类,其它药物如文拉法辛、瑞波西汀、莫达非尼、奥卡西平、普萘洛尔等也被尝试用于治疗成人ADHD,并取得一定疗效。%Attention deficit/hyperactivity disorder(ADHD)is the most frequently diagnosed neuro-developmental disorder in children and most of the children ADHD cases can persist to adulthood. The DSM-5 developed and published by American Psychiatric Association(APA)at 2012 firstly gives the more appropriate diagnosis criteria and regulates pharmacotherapies for adult ADHD. The currently used medications include neural stimulants(e.g. methylphenidate and amphetamines)and non-stimulants(e.g. atomoxetine,buproprion and tricyclic antidepressants). Other medications such as venlafaxine,reboxetine,modafinil,oxcarbazepine and propranolol are also tried to treat adult ADHD and showed a certain effects.

  6. Epidemiology of Depression for Clinicians.

    Bromberger, Joyce T.; Costello, Elizabeth Jane

    1992-01-01

    Reviews epidemiology of depression and ways this information can be useful for clinicians. Defines frequently used epidemiological terms; presents prevalence rates and risk factors; discusses impact and consequences of depression; and suggests arenas for prevention, early intervention, and treatment that can help clinicians in their everyday work.…

  7. CEDR: Comprehensive Epidemiologic Data Resource

    1993-08-01

    The Department of Energy (DOE) and its predecessor agencies have a long history of epidemiologic research programs. The main focus of these programs has been the Health and Mortality Study of the DOE work force. This epidemiologic study began in 1964 with a feasibility study of workers at the Hanford facility. Studies of other populations exposed to radiation have also been supported, including the classic epidemiologic study of radium dial painters and studies of atomic bomb survivors. From a scientific perspective, these epidemiologic research program have been productive, highly credible, and formed the bases for many radiological protection standards. Recently, there has been concern that, although research results were available, the data on which these results were based were not easily obtained by interested investigators outside DOE. Therefore, as part of an effort to integrate and broaden access to its epidemiologic information, the DOE has developed the Comprehensive Epidemiologic Data Resource (CEDR) Program. Included in this effort is the development of a computer information system for accessing the collection of CEDR data and its related descriptive information. The epidemiologic data currently available through the CEDAR Program consist of analytic data sets, working data sets, and their associated documentation files. In general, data sets are the result of epidemiologic studies that have been conducted on various groups of workers at different DOE facilities during the past 30 years.

  8. The epidemiology of head injury in Cantabria.

    Vázquez-Barquero, A; Vázquez-Barquero, J L; Austin, O; Pascual, J; Gaite, L; Herrera, S

    1992-11-01

    The epidemiology of head injury was studied in Cantabria, Spain, using a methodological design consisting of a cross-selectional analysis of one year of duration and an additional one year follow-up of all the patients included in the initial sample. The 477 cases identified represent a rate of 91/100,000, with males showing a head injury rate 2.7 times higher that than for females. Sixty per cent of all cases involved traffic accidents, falls accounted for 24% and industrial accidents were the cause in 8%. The annual age-adjusted mortality rate was 19.7/100,000. Over 92% of all deaths occurred prior to hospital admission. The presence of alcohol intoxication was evaluated in 211 cases by determining the osmolar gap. It was found that 51% of all the cases examined presented clear evidence of acute alcohol intoxication. PMID:1294388

  9. [Descriptive epidemiology of urolithiasis].

    Kodama, H; Ohno, Y

    1989-06-01

    In this paper, urolithiasis is remarked from the standpoint of descriptive epidemiology, which examines the frequency distribution of a given disease in a population in terms of time, place and personal characteristics with an aim of identifying risk factors or some clues to the etiology. Some descriptive epidemiological features of urolithiasis are summarized. Prevalence rate is around 4% (4-15% in males and 4-8% in females), and incidence rate varies from area to area: 53.2 per 100,000 population in 1975 in Japan, 364 in 1976 in Malaysia, and 540 in 1979 in West Germany. Prevalence and/or incidence rates have, in general, increased in the developed countries since World War II and in the developing countries as well, where upward trends are quite analogous to the trends observed in the nineteenth century in Europe. Recurrence rate, which is much higher in males than in females, ranges from 31% to 75%, depending on the follow-up periods. In the industrialized countries, upper urinary (renal and ureteral) stones account for more than 90% of total stones, which are ordinarily calcium complexes in composition. More common in the developing countries are lower urinary (bladder and urethral) stones, frequently composed of magnesium ammonium phosphate, which indicates a close association with urinary tract infections. Variations in frequency are evident by season and by region within a country. Age and sex differentials in urinary stone formers are substantial: more common in males 30-40 years old in the industrialized countries and in children under 10 years old in the developing countries. Racial differentials are also noted; blacks appear to suffer less frequently than whites. Stone formers experience more frequent episodes of stone formation in their family members, particularly father and brothers, than non-stone formers. These findings on racial differentials and family preponderance suggest the possible relevance of genetic factors in stone formation. Stone

  10. Parasomnias: epidemiology and management.

    Wills, Laurel; Garcia, John

    2002-01-01

    The category of common sleep disorders known as parasomnias includes disorders of arousal, rapid eye movement (REM) sleep behaviour disorder (RBD), nocturnal seizures, rhythmic movement disorder, and tooth grinding or 'bruxism'. Parasomnias are all characterised as undesirable physical or behavioural phenomena occurring during the sleep period. Although these conditions can be distressing and, in some cases, hazardous to the sleeper and his or her bed partner, it is important to recognise that parasomnias are diagnosable and treatable in the vast majority of patients. Evaluation begins with a careful clinical interview with the sleeper and a family member to elucidate the frequency, duration, description and timing after sleep onset of these behavioural events. Disorders of arousal are the most common type of parasomnia and cover a spectrum from calm sleepwalking to emotionally agitated or complex behaviours, such as dressing or driving, for which the patient usually has no memory upon awaking. 'Sleep terrors' are quite common in young children and are often outgrown. Disorders of arousal represent a partial, as opposed to a full, awakening from deep non-REM sleep, typically occurring within the first 60 to 90 minutes after sleep onset. RBD is characterised clinically by a history of dream-enacting behaviour, and the patient may recall dream content. REM sleep periods typically occur in the latter half of the night. Physiologically, RBD results from a lack of the normal muscle atonia that is associated with REM sleep. RBD has been linked to a number of other neurological conditions; thus, a careful review of systems and a physical examination are crucial. A formal laboratory sleep study or polysomnogram with an expanded electroencephalographic montage can help distinguish among non-REM and REM parasomnias and nocturnal seizures. The latter may manifest clinically as arousals from sleep associated with vocalisation and/or complex behaviours. Rhythmic movement

  11. Delay Adjusted Incidence Infographic

    This Infographic shows the National Cancer Institute SEER Incidence Trends. The graphs show the Average Annual Percent Change (AAPC) 2002-2011. For Men, Thyroid: 5.3*,Liver & IBD: 3.6*, Melanoma: 2.3*, Kidney: 2.0*, Myeloma: 1.9*, Pancreas: 1.2*, Leukemia: 0.9*, Oral Cavity: 0.5, Non-Hodgkin Lymphoma: 0.3*, Esophagus: -0.1, Brain & ONS: -0.2*, Bladder: -0.6*, All Sites: -1.1*, Stomach: -1.7*, Larynx: -1.9*, Prostate: -2.1*, Lung & Bronchus: -2.4*, and Colon & Rectum: -3/0*. For Women, Thyroid: 5.8*, Liver & IBD: 2.9*, Myeloma: 1.8*, Kidney: 1.6*, Melanoma: 1.5, Corpus & Uterus: 1.3*, Pancreas: 1.1*, Leukemia: 0.6*, Brain & ONS: 0, Non-Hodgkin Lymphoma: -0.1, All Sites: -0.1, Breast: -0.3, Stomach: -0.7*, Oral Cavity: -0.7*, Bladder: -0.9*, Ovary: -0.9*, Lung & Bronchus: -1.0*, Cervix: -2.4*, and Colon & Rectum: -2.7*. * AAPC is significantly different from zero (p<.05). Rates were adjusted for reporting delay in the registry. www.cancer.gov Source: Special section of the Annual Report to the Nation on the Status of Cancer, 1975-2011.

  12. [Comorbidity of eating disorders and bipolar affective disorders].

    Kamińska, Katarzyna; Rybakowski, Filip

    2006-01-01

    Eating disorders--anorexia nervosa, bulimia nervosa and eating disorders not otherwise specified (EDNOS) occur usually in young females. The significant pathogenic differences between patients who only restrict food, and patients with binge eating and compensatory behaviours, such as vomiting and purging were described. The prevalence of bipolar affective disorders--especially bipolar II and bipolar spectrum disorders (BS) may reach 5% in the general population. About half of the depressive episodes are associated with a "mild" bipolar disorder, and such a diagnosis is suggested by impulsivity and mood-instability. Previously, majority of research on the comorbidity between eating and affective disorders focused on depressive symptomatology, however difficulties in the reliable assessment of hypomania may obfuscate the estimation of the co-occurrence of eating disorders with BS. Epidemiological studies suggest the association between BS and eating disorders with binge episodes (bulimia nervosa, anorexia- bulimic type and EDNOS with binge episodes). Co-occurrence of such disorders with depressive symptoms probably suggests the diagnosis of BS, not recurrent depression. Bulimic behaviours, impulsivity and affective disorders might be related to the impairment of the serotonergic neurotransmission, which may result from the genetic vulnerability and early life trauma. Currently, the first-line pharmacological treatment of co-occurring eating disorders with binge episodes and BS are selective serotonin reuptake inhibitors. However in some cases, the use of mood-stabilising agents as monotherapy or in combination with serotonergic drugs may be helpful. PMID:17037812

  13. Epidemiology and disease burden from allergic disease in Scotland:analyses of national databases

    Anandan, C; R. Gupta; Simpson, C.R.; Fischbacher, C; Sheikh, A.

    2009-01-01

    There are ongoing concerns about the quality of care provided to patients with allergic disorders in Scotland, but there are relatively few reliable data on the overall disease burden. We sought to: (1) describe the incidence, prevalence and outcome of allergic disorders; (2) estimate healthcare burden and costs; and (3) investigate ethnic variations in the epidemiology and outcomes from allergic disorders in Scotland.Methods Data sources: national surveys; primary care data; prescribing and ...

  14. Marital Adjustment, Parental Functioning, and Emotional Sharing in War Veterans

    Solomon, Zahava; Debby-Aharon, Shimrit; Zerach, Gadi; Horesh, Danny

    2011-01-01

    The current study aimed to examine the implications of posttraumatic stress disorder symptoms and emotional sharing in marital adjustment and parental functioning among Israeli veterans of the 1982 Lebanon War. The sample consisted of combat stress reaction (CSR) veterans (n = 264) and non-CSR veterans (n = 209). Results show that traumatized…

  15. The Epidemiology of Sarcoma

    Burningham Zachary

    2012-10-01

    Full Text Available Abstract Sarcomas account for over 20% of all pediatric solid malignant cancers and less than 1% of all adult solid malignant cancers. The vast majority of diagnosed sarcomas will be soft tissue sarcomas, while malignant bone tumors make up just over 10% of sarcomas. The risks for sarcoma are not well-understood. We evaluated the existing literature on the epidemiology and etiology of sarcoma. Risks for sarcoma development can be divided into environmental exposures, genetic susceptibility, and an interaction between the two. HIV-positive individuals are at an increased risk for Kaposi’s sarcoma, even though HHV8 is the causative virus. Radiation exposure from radiotherapy has been strongly associated with secondary sarcoma development in certain cancer patients. In fact, the risk of malignant bone tumors increases as the cumulative dose of radiation to the bone increases (p for trend

  16. [Epidemiology of "sick buildings"].

    Sterling, T D; Collett, C; Rumel, D

    1991-02-01

    The indoor environment of modern buildings, especially those designed for commercial and administrative purposes, constitutes a unique ecological niche with its own biochemical environment, fauna and flora. Sophisticated construction methods and the new materials and machinery required to maintain the indoor environment of these enclosed structures produce a large number of chemical by-products and permit the growth of many different microorganisms. Because modern office buildings are sealed, the regulation of humidification and temperature of ducted air presents a dilemma, since difference species of microorganisms flourish at different combinations of humidity and temperature. If the indoor environment of modern office buildings is not properly maintained, the environment may become harmful to its occupants' health. Such buildings are classified as "Sick Buildings". A review of the epidemiology of building illness is presented. The etiology of occupant illnesses, sources of toxic substances, and possible methods of maintaining a safe indoor environment are described. PMID:1784964

  17. Epidemiological studies on syncope

    Ruwald, Martin Huth

    2013-01-01

    The epidemiology and prognosis of ''fainting'' or syncope has puzzled physicians over the years. Is fainting dangerous? This is a question often asked by the patient--and the answer is ''it depends on a lot of things''. The diverse pathophysiology of syncope and the underlying comorbidites of the...... from smaller studies from different clinical settings with wide differences in patient morbidity. Through the extensive Danish registries we examined the characteristics and prognosis of the patients hospitalized due to syncope in a nationwide study. The aims of the present thesis were to investigate...... thesis demonstrated that the ICD-10 discharge diagnosis could reliably identify a cohort of patients admitted for syncope and that the discharge code carried a high number of unexplained cases despite use of numerous tests. The last studies showed that syncope is a common cause for hospital contact in...

  18. Epidemiology of massive transfusion

    Halmin, M A; Chiesa, F; Vasan, S K;

    2015-01-01

    -registers. We included all patients receiving 10 or more red blood cell (RBC) transfusions in up to 2 calendar days, in Sweden 1987-2010 and in Denmark 1996-2010. The patients were followed throughout 2012. Descriptive statistics were used to characterize the patients and the indications for massive transfusion......Background: In recent years, massive transfusion protocols have received increasing attention. The potential risks associated with massive transfusion have been discussed and associations with both increased morbidity and mortality have been reported. However there is a paucity of comprehensive...... data on massively transfused patients and their long-term outcomes. A better characterization of the epidemiology of massive transfusion is warranted to improve clinical decision making and to guide future studies. Aims: The aim of this study was to estimate the incidence of massive transfusion...

  19. Epidemiological studies on syncope

    Ruwald, Martin Huth

    2013-01-01

    The epidemiology and prognosis of ''fainting'' or syncope has puzzled physicians over the years. Is fainting dangerous? This is a question often asked by the patient--and the answer is ''it depends on a lot of things''. The diverse pathophysiology of syncope and the underlying comorbidites...... from smaller studies from different clinical settings with wide differences in patient morbidity. Through the extensive Danish registries we examined the characteristics and prognosis of the patients hospitalized due to syncope in a nationwide study. The aims of the present thesis were to investigate...... thesis demonstrated that the ICD-10 discharge diagnosis could reliably identify a cohort of patients admitted for syncope and that the discharge code carried a high number of unexplained cases despite use of numerous tests. The last studies showed that syncope is a common cause for hospital contact...

  20. Epidemiology of acne vulgaris.

    Bhate, K; Williams, H C

    2013-03-01

    Despite acne being an almost universal condition in younger people, relatively little is known about its epidemiology. We sought to review what is known about the distribution and causes of acne by conducting a systematic review of relevant epidemiological studies. We searched Medline and Embase to the end of November 2011. The role of Propionibacterium acnes in pathogenesis is unclear: antibiotics have a direct antimicrobial as well as an anti-inflammatory effect. Moderate-to-severe acne affects around 20% of young people and severity correlates with pubertal maturity. Acne may be presenting at a younger age because of earlier puberty. It is unclear if ethnicity is truly associated with acne. Black individuals are more prone to postinflammatory hyperpigmentation and specific subtypes such as 'pomade acne'. Acne persists into the 20s and 30s in around 64% and 43% of individuals, respectively. The heritability of acne is almost 80% in first-degree relatives. Acne occurs earlier and is more severe in those with a positive family history. Suicidal ideation is more common in those with severe compared with mild acne. In the U.S.A., the cost of acne is over 3 billion dollars per year in terms of treatment and loss of productivity. A systematic review in 2005 found no clear evidence of dietary components increasing acne risk. One small randomized controlled trial showed that low glycaemic index (GI) diets can lower acne severity. A possible association between dairy food intake and acne requires closer scrutiny. Natural sunlight or poor hygiene are not associated. The association between smoking and acne is probably due to confounding. Validated core outcomes in future studies will help in combining future evidence. PMID:23210645

  1. Epidemiology of HCV infection.

    Baldo, V; Baldovin, T; Trivello, R; Floreani, A

    2008-01-01

    It is estimated that approximately 130-170 million people worldwide are infected with hepatitis C virus (HCV). According to data from WHO community and blood donor surveys, the African and Eastern Mediterranean countries report the highest prevalence rates (>10%). The rates of infection in the general population and the incidence of newly-acquired cases indicate an appreciable change in the epidemiology of the infection in recent years. Prior to the widespread screening of blood donations, infected blood and blood products represented a common source of infection. On the other hand, the high peak in HCV antibodies among the elderly in Italian epidemiological studies on the population at large reflects a cohort effect due to an epidemic of HCV infection occurring after the Second World War. According to data reported by the CDC Surveillance System, the incidence of acute hepatitis C has declined since the late 1980s. In 2005, as in previous years, the majority of such cases in North America and Northern Europe occurred among young adults and injected drug use was the most common risk factor. Other, less commonly reported modes of HCV acquisition are occupational exposure to blood, high-risk sexual activity, tattooing, body piercing and other forms of skin penetration. Finally, the overall rate of mother-to-child transmission from HCV-infected, HIV-negative mothers has been estimated at around 5% (coinfection with HIV raises this figure to 19.4%). HCV prevention relies on identifying and counseling uninfected persons at risk of contracting hepatitis C. PMID:18673187

  2. 天津市中小学教师咽喉疾病及嗓音状况调查分析%Epidemiological Study of Throat Disease and Voice Disorders in Teachers in Tianjin

    黄永望; 谷津津; 吴双; 耿淑梅

    2011-01-01

    目的 了解天津市中小学教师职业用嗓情况,为制定嗓音疾病防治和康复计划提供科学依据.方法 对天津市71所中小学校及幼儿园的3 555名教师进行了咽喉疾病及嗓音健康状况普查(包括问卷调查及耳鼻咽喉专科检杳).结果 教师咽喉及嗓音疾病总患病率为46.6%,其中慢性咽炎占28.0%,其次为慢性喉炎(17.2%)和慢性扁桃体炎(6.2%),声带小结和声带息肉分别占3.6%和1.3%.嗓音疾病患病率随教龄增长而增高,男性高于女性,吸烟者高于不吸烟者,中学教师患病率低于小学与幼儿园教师患病率,差异具有统计学意义(P<0.05);而小学和幼儿园教师患病率差异无统计学意义(P>0.05).结论 教师是咽喉及嗓音疾病的高发人群,应加强对教师进行咽喉及嗓音疾病的预防宣传和保健工作.%Objective A prevalence survey of professional vocalization of teachers was conducted in Tianjin to provide scientific data for the future prevention and treatment of voicing problems. Methods 3 555 teachers from 71 schools of Tianjin were included in this study, including questionnaire and otolaryngology test. Results The prevalence of voice disorders was 46.6%. The prevalence of various voice disorders were as follows: 28. 0% for chronic pharyngitis, 17. 2% for chroniclaryngitis,6.2% for chronic tonsillitis,3.6% for vocal nodules and 1.3% for vocal polyp respectively. There was a significant difference in prevalence between males and females, between smokers and non-smokers, between different school age groups, between middle-school teachers and primary-school teachers and nursery-school teachers. But there was no significant difference in prevalence between primary- school teachers and nursery- school teachers. Conclusion The studies have revealed that the teachers had a higher occupational risk ,The main risk factors for voice disorders were vocal loading and vocal abuse. The government, the school and the

  3. Epidemiology and genetics of dilated cardiomyopathy in the Indian context

    Ushasree B

    2009-07-01

    Full Text Available Background: Dilated cardiomyopathy (DCM still remains to be a poorly understood and less analyzed group of cardiac-muscle disorders when compared to hypertrophic cardiomyopathy (HCM. Also, the vast clinical heterogeneity among the patients has rendered the small and isolated kindred studies less informative on the genetics and epidemiology of DCM. Aim of the study: The study aimed at understanding the epidemiology and genetics of DCMs in the Indian context. Materials and methods/ Statistical analysis: One hundred seven DCM patients and 105 healthy individuals were included in the study for epidemiological and genetic risk factor identification and to fit the possible mode of inheritance. Single′s ascertainment methodology for segregation analysis and Penrose frequency estimates were followed to evaluate for the role of specific epidemiological factors in the disease etiology. Chi-square analysis was carried out to interpret the results statistically. Results and Conclusion: Our study suggests that epidemiological factors like gender, age at onset and vegetarian diet in conjunction with sarcomere gene mutations may play a role in the disease expression. Similarly, segregation analysis for the possible mode of inheritance showed a deviation from the autosomal dominant mode of inheritance, strengthening the underlying genetic heterogeneity of DCM.

  4. 急诊科护士创伤后应激障碍流行病学特点及危险因素%Epidemiology characteristic and risk factors of post traumatic stress disorder of nurses in emergency department

    林琳; 何国平

    2006-01-01

    创伤后应激障碍(Post traumatic stress disorder,PTSD)是对创伤等严重应激因素的一种重度精神反应,它发生在经历过灾难性事件的人群或特殊职业人群,对PTSD的研究利于结合医学、护理学与社会心理学知识来提高疗效.综述了国内外文献中急诊科护士PTSD的流行病学特点及危险因素,认为急诊科护士PTSD发生率高于一般人群,其危险因素包括创伤性事件、与工作相关的压力源、个体易感因素、社会支持及社会历史文化因素.指出护士是护理事业的主体,其身心健康直接关系到护理服务质量,呼吁社会各界高度重视急诊科护士PTSD问题,关注护士的身心健康,促进急救护理事业的发展.

  5. Metric-adjusted skew information

    Liang, Cai; Hansen, Frank

    2010-01-01

    We give a truly elementary proof of the convexity of metric-adjusted skew information following an idea of Effros. We extend earlier results of weak forms of superadditivity to general metric-adjusted skew information. Recently, Luo and Zhang introduced the notion of semi-quantum states on a...... bipartite system and proved superadditivity of the Wigner-Yanase-Dyson skew informations for such states. We extend this result to the general metric-adjusted skew information. We finally show that a recently introduced extension to parameter values 1 < p = 2 of the WYD-information is a special case of...... (unbounded) metric-adjusted skew information....

  6. Adjustment computations spatial data analysis

    Ghilani, Charles D

    2011-01-01

    the complete guide to adjusting for measurement error-expanded and updated no measurement is ever exact. Adjustment Computations updates a classic, definitive text on surveying with the latest methodologies and tools for analyzing and adjusting errors with a focus on least squares adjustments, the most rigorous methodology available and the one on which accuracy standards for surveys are based. This extensively updated Fifth Edition shares new information on advances in modern software and GNSS-acquired data. Expanded sections offer a greater amount of computable problems and their worked solu

  7. Epidemiology and treatment of 23 musicians with task specific tremor

    Lee, André; Furuya, Shinichi; Altenmüller, Eckart

    2014-01-01

    Background Task specific tremors in musicians have been mainly described as primary bowing tremor in string instrumentalists in relatively small sample sizes. Our aim was to describe epidemiology, risk factors, phenomenology and treatment options of this disorder in 23 musicians of different instruments. Methods We included 23 professional musicians (4 female, 19 male; mean age 51.5 ± 11.4 years) with a TSTM. During anamnesis, clinical examination, by mail or via telephone patients were asked...

  8. Methodologic frontiers in environmental epidemiology.

    Rothman, K J

    1993-01-01

    Environmental epidemiology comprises the epidemiologic study of those environmental factors that are outside the immediate control of the individual. Exposures of interest to environmental epidemiologists include air pollution, water pollution, occupational exposure to physical and chemical agents, as well as psychosocial elements of environmental concern. The main methodologic problem in environmental epidemiology is exposure assessment, a problem that extends through all of epidemiologic research but looms as a towering obstacle in environmental epidemiology. One of the most promising developments in improving exposure assessment in environmental epidemiology is to find exposure biomarkers, which could serve as built-in dosimeters that reflect the biologic footprint left behind by environmental exposures. Beyond exposure assessment, epidemiologists studying environmental exposures face the difficulty of studying small effects that may be distorted by confounding that eludes easy control. This challenge may prompt reliance on new study designs, such as two-stage designs in which exposure and disease information are collected in the first stage, and covariate information is collected on a subset of subjects in state two. While the analytic methods already available for environmental epidemiology are powerful, analytic methods for ecologic studies need further development. This workshop outlines the range of methodologic issues that environmental epidemiologists must address so that their work meets the goals set by scientists and society at large. PMID:8206029

  9. 南京市3~6岁儿童睡眠问题流行病学调查%Epidemiological investigation of sleep disorders for the children of 3 ~ 6 years in Nanjing city

    谢海虹; 郭锡熔; 曲红明; 祝丽珺

    2012-01-01

    [Objective] To investigate the sleep conditions and correlative factors of children 3~6 years old children in Nanjing. [Method] 1 327 children aged 3 - 6 years old were randomly selected for investigation in Nanjing. [Results] There was a higher prevalenee rate of sleep disorders in children in Nanjing city than the level of investigations in other cities,it was 52. 67%. Among their symptoms of sleep disorder,hyperhidrosis was 34. 51% ,molar teeth 14. 47% restless sleep 10. 78% , sleep snoring 10. 32% , night talking 9. 34% , mouth breathing 6. 41% , limber spasm 4. 60% , sleep long time in daytime and less in night 2. 03% ,screeching or crying during sleeping 2. 03% ,going to sleep earlyl. 96% ,choke gargling 1. 28%,night awakenings 0. 98% .limber spasm 0. 38% ,sleep apnea 0. 23%,sleep walking 0. 08%. The prevalences of hyperhidrosis,sleep long time in daytime and less in night of boys were larger than girls. The prevalence of night talking of girls was larger than boys. The main factors those affected the sleep disorders were 5 including the having diseases,feelings before sleep,sleep time,sleep posture,playing games outside. There were many factors those affected the sleep problems of children including children's age,heredity and environmental factors.%[目的]了解南京市3~6岁儿童睡眠问题发生情况、影响因素及其对儿童的危害,为防治儿童睡眠问题提供依据. [方法]随机抽取南京市1 327名3~6岁儿童进行睡眠状况的问卷调查. [结果]南京市3~6岁儿童睡眠问题发生率为52.67%,其中男童为56.10%,女童为48.60%,两者间差异有统计学意义;睡眠时各症状发生率为多汗34.51%,磨牙14.47%,辗转不安10.78%,打呼噜10.32%,说梦话9.34%,用口呼吸6.41%,肢体抽动4.60%,白天睡得多夜间清醒2.03%,睡眠中出现尖叫、哭喊2.03%,入睡过早或傍晚入睡1.96%,喉头哽咽1.28%,睡眠中轻微刺激即惊醒0.98%,有痉挛性肢体抽动0.38

  10. Epidemiology of myopia

    Foster, P J; Jiang, Y.

    2014-01-01

    Myopia is one of the most prevalent disorders of the eye. Higher myopia is associated with comorbidities that increase risks of severe and irreversible loss of vision, such as retinal detachment, subretinal neovascularization, dense cataract, and glaucoma. In recent years, reports from population-based prevalence studies carried out in various geographical areas now give a clear picture of the current distribution of refractive error. The scarcity of data from well-designed longitudinal cohor...

  11. Psoriasis: epidemiology, natural history, and differential diagnosis

    Basko-Plluska JL

    2012-09-01

    Full Text Available Juliana L Basko-Plluska, Vesna Petronic-RosicDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USAAbstract: Psoriasis is a chronic, immune-mediated, inflammatory disease which affects primarily the skin and joints. It occurs worldwide, but its prevalence varies considerably between different regions of the world. Genetic susceptibility as well as environmental factors play an important role in determining the development and prognosis of psoriasis. Genome-wide association studies have identified many genetic loci as potential psoriasis susceptibility regions, including PSORS1 through PSORS7. Histocompatibility antigen (HLA studies have also identified several HLA antigens, with HLA-Cw6 being the most frequently associated antigen. Epidemiological studies identified several modifiable risk factors that may predispose individuals to developing psoriasis or exacerbate pre-existing disease. These include smoking, obesity, alcohol consumption, diet, infections, medications and stressful life events. The exact mechanism by which they trigger psoriasis remains to be elucidated; however, existing data suggest that they are linked through Th1-mediated immunological pathways. The natural history of psoriasis varies depending on the clinical subtype as well as special circumstances, including pregnancy and HIV infection. In general, psoriasis is a chronic disease with intermittent remissions and exacerbations. The differential diagnosis is vast and includes many other immune-mediated, inflammatory disorders.Keywords: psoriasis, epidemiology, natural history, differential diagnosis

  12. Variance Adjusted Actor Critic Algorithms

    Tamar, Aviv; Mannor, Shie

    2013-01-01

    We present an actor-critic framework for MDPs where the objective is the variance-adjusted expected return. Our critic uses linear function approximation, and we extend the concept of compatible features to the variance-adjusted setting. We present an episodic actor-critic algorithm and show that it converges almost surely to a locally optimal point of the objective function.

  13. Mood Adjustment via Mass Communication.

    Knobloch, Silvia

    2003-01-01

    Proposes and experimentally tests mood adjustment approach, complementing mood management theory. Discusses how results regarding self-exposure across time show that patterns of popular music listening among a group of undergraduate students differ with initial mood and anticipation, lending support to mood adjustment hypotheses. Describes how…

  14. Bayes linear covariance matrix adjustment

    Wilkinson, Darren J

    1995-01-01

    In this thesis, a Bayes linear methodology for the adjustment of covariance matrices is presented and discussed. A geometric framework for quantifying uncertainties about covariance matrices is set up, and an inner-product for spaces of random matrices is motivated and constructed. The inner-product on this space captures aspects of our beliefs about the relationship between covariance matrices of interest to us, providing a structure rich enough for us to adjust beliefs about unknown matrices in the light of data such as sample covariance matrices, exploiting second-order exchangeability and related specifications to obtain representations allowing analysis. Adjustment is associated with orthogonal projection, and illustrated with examples of adjustments for some common problems. The problem of adjusting the covariance matrices underlying exchangeable random vectors is tackled and discussed. Learning about the covariance matrices associated with multivariate time series dynamic linear models is shown to be a...

  15. An epidemiological study on Functional Bowel Disorders in Rural Areas of Lankao County in Henan Province%河南省兰考县农村地区功能性肠病的流行病学调查

    王利营; 杨云生; 曹晓鹏; 彭丽华; 蔡赐河; 蔡顺天; 张雷

    2012-01-01

    目的:调查河南省兰考县农村地区功能性肠病(functional bowel disorders,FBD)流行病学状况.方法:采用普查方法,对该地区6个村庄全部进行入户问卷调查,按照罗马III功能性胃肠病诊断标准统计FBD患病率,并按照性别、年龄、体质量指数和生活习惯等分组,进行相关危险因素分析.结果:实际共调查3 032例,其中男性1531例,女性1501例;年龄18~109岁.共检出FBD 137例(4.52%),女性FBD患病率(5.13%)高于男性(3.92%),但两者差异无统计学意义(P=0.108);男性肠易激综合征(irritable bowel syndrome,IBS)患病率显著低于女性(P<0.05);FBD患病率随年龄增长而升高,60岁以上组达高峰(8.50%,P<0.001),高龄是IBS、功能性腹泻的危险因素;功能性腹胀、IBS及FBD患病率均以消瘦组最高(P<0.05);较少规律进食与FBD有关,较少规律进食、较多进食生冷或辛辣食物是非特异性FBD的危险因素(P<0.05);多元回归分析发现高龄、焦虑和抑郁是FBD的危险因素.结论:河南省兰考县农村地区FBD患病率较低,年龄、不良生活方式是FBD的危险因素,FBD多伴焦虑、抑郁倾向.%Objective:To investigate the prevalence of functional bowel disorders (FBD) in the population of the countryside of Lankao county in Henan province. Methods: A census was carried out in 6 villages of the area, using the Rome Ⅲ criteria to assess the prevalence of FBD and to analyze their related risk factors. Results: A total of 3032 residents (1531 males, 1501 females) were investigated. Their age varied from 18 years to 109 years. Of the residents surveyed, 137(4. 52%) were diagnosed with FBD. The prevalence of FBD in females (5. 13%) was higher than that in males (3. 92%), but the difference was not significant (P = 0. 108). However, the prevalence of irritable bowel syndrome (IBS) in males was significantly lower than that in females (P<0. 05). The rate of FBD increased with age, reaching the peak of 8. 50% at the age of

  16. Epidemiology of gastric cancer

    Katherine D Crew; Alfred I Neugut

    2006-01-01

    The incidence and mortality of gastric cancer have fallen dramatically in US and elsewhere over the past several decades. Nonetheless, gastric cancer remains a major public health issue as the fourth most common cancer and the second leading cause of cancer death worldwide. Demographic trends differ by tumor location and histology. While there has been a marked decline in distal, intestinal type gastric cancers, the incidence of proximal, diffuse type adenocarcinomas of the gastric cardia has been increasing, particularly in the Western countries. Incidence by tumor sub-site also varies widely based on geographic location, race, and socioeconomic status. Distal gastric cancer predominates in developing countries, among blacks, and in lower socioeconomic groups, whereas proximal tumors are more common in developed countries, among whites, and in higher socio-economic classes. Diverging trends in the incidence of gastric cancer by tumor location suggest that they may represent two diseases with different etiologies. The main risk factors for distal gastric cancer include Helicobacter pylori (H pylori) infection and dietary factors, whereas gastroesophageal reflux disease and obesity play important roles in the development of proximal stomach cancer. The purpose of this review is to examine the epidemiology and risk factors of gastric cancer, and to discuss strategies for primary prevention.

  17. [Epidemiology of teeth hypersensitivity].

    Lutskaia, I K; Zinovenko, O G; Kovalenko, I P

    2015-01-01

    A clinical examination of 98 patients aged 20 to 75 years was carried out to identifyclinical and epidemiological features of hard tooth tissueshypersensitivity. The survey found out what stimuli (cold, hot, sour, mechanical, chemical) cause the appearance of dental hyperesthesia. The detailed survey of the affected area aimed to determine the presence of dental caries, gingival recession, wedge-shaped defects, erosions, microcracks and chipped enamel, as well as wear of the tooth crown. Forty-threepatients of 98 (43.88%) had tooth sensitivity. Most affected age group was 25-34 years (33%). Among patients studied with hyperesthesia 86% complained of pain. It was establishedthat dental hyperesthesia most often causes an intense, but quickly passing pain response, wherein upon exposure of several types of stimuli. Teeth with high sensitivity showed signs of abrasion (74.1%), most often--on the vestibular surface (44.4%). Patients under 45 years had notable cracks and wedge-shaped defects. In patients 45 years and older cracks and increased abrasion of hard dental tissues was seen. PMID:26271696

  18. Radiobiology and Epidemiology

    Desaintes, C; Holmstock, L

    2001-04-01

    The main objectives of research in the field of radiobiology and epidemiology performed at the Belgian Nuclear Research Centre SCK-CEN are: (1) to study cancer mortality in nuclear workers in Belgium and to co-ordinate the Belgian contribution to the 'International Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry'; (2) to elucidate the molecular basis of individual susceptibility to ionizing radiation in mammalian embryo during the early phases of its development; (3) to assess the genetic risk of maternal exposure to ionizing radiation; (4) to elucidate the cellular mechanisms leading to brain damage after prenatal irradiation; (5) to monitor the early variations of gene expression induced by ionising radiation and cytokines; (6) to evaluate the use of cytokines and natural substances for improving radiotherapy protocols; (6) to advise authorities and to provide the general population with adequate information concerning the health risk arising from radiation exposure. Progress and major achievements in these topical areas in 2000 are reported.

  19. Shigellosis: Epidemiology in India.

    Taneja, Neelam; Mewara, Abhishek

    2016-05-01

    Shigellosis is one of the major causes of diarrhoea in India. The accurate estimates of morbidity and mortality due to shigellosis are lacking, though it is endemic in the country and has been reported to cause many outbreaks. The limited information available indicates Shigella to be an important food- borne pathogen in India. S. flexneri is the most common species, S. sonnei and non-agglutinable Shigellae seem to be steadily surfacing, while S. dysenteriae has temporarily disappeared from the northern and eastern regions. Antibiotic-resistant strains of different Shigella species and serotypes have emerged all over the world. Especially important is the global emergence of multidrug resistant Shigellae, notably the increasing resistance to third generation cephalosporins and fluoroquinolones, and also azithromycin. This calls for a continuous and strong surveillance of antibiotic resistance across the country for periodic updation of the local antibiograms. The prevention of shigellosis is desirable as it will substantially reduce the morbidity associated with diarrhoea in the country. Public health measures like provision of safe water and adequate sanitation are of immense importance to reduce the burden of shigellosis, however, the provision of resources to develop such an infrastructure in India is a complex issue and will take time to resolve. Thus, the scientific thrust should be focused towards development of a safe and affordable multivalent vaccine. this review is focused upon the epidemiology, disease burden and the therapeutic challenges of shigellosis in Indian perspective. PMID:27487999

  20. Radiobiology and Epidemiology

    The main objectives of research in the field of radiobiology and epidemiology performed at the Belgian Nuclear Research Centre SCK-CEN are: (1) to study cancer mortality in nuclear workers in Belgium and to co-ordinate the Belgian contribution to the 'International Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry'; (2) to elucidate the molecular basis of individual susceptibility to ionizing radiation in mammalian embryo during the early phases of its development; (3) to assess the genetic risk of maternal exposure to ionizing radiation; (4) to elucidate the cellular mechanisms leading to brain damage after prenatal irradiation; (5) to monitor the early variations of gene expression induced by ionising radiation and cytokines; (6) to evaluate the use of cytokines and natural substances for improving radiotherapy protocols; (6) to advise authorities and to provide the general population with adequate information concerning the health risk arising from radiation exposure. Progress and major achievements in these topical areas in 2000 are reported

  1. Shigellosis: Epidemiology in India

    Taneja, Neelam; Mewara, Abhishek

    2016-01-01

    Shigellosis is one of the major causes of diarrhoea in India. The accurate estimates of morbidity and mortality due to shigellosis are lacking, though it is endemic in the country and has been reported to cause many outbreaks. The limited information available indicates Shigella to be an important food-borne pathogen in India. S. flexneri is the most common species, S. sonnei and non-agglutinable shigellae seem to be steadily surfacing, while S. dysenteriae has temporarily disappeared from the northern and eastern regions. Antibiotic-resistant strains of different Shigella species and serotypes have emerged all over the world. Especially important is the global emergence of multidrug resistant shigellae, notably the increasing resistance to third generation cephalosporins and fluoroquinolones, and also azithromycin. This calls for a continuous and strong surveillance of antibiotic resistance across the country for periodic updation of the local antibiograms. The prevention of shigellosis is desirable as it will substantially reduce the morbidity associated with diarrhoea in the country. Public health measures like provision of safe water and adequate sanitation are of immense importance to reduce the burden of shigellosis, however, the provision of resources to develop such an infrastructure in India is a complex issue and will take time to resolve. Thus, the scientific thrust should be focused towards development of a safe and affordable multivalent vaccine. This review is focused upon the epidemiology, disease burden and the therapeutic challenges of shigellosis in Indian perspective. PMID:27487999

  2. Modeling Corporate Epidemiology

    Waber, Benjamin; Cebrian, Manuel; Crane, Riley; Danon, Leon; Pentland, Alex

    2010-01-01

    Corporate responses to illness is currently an ad-hoc, subjective process that has little basis in data on how disease actually spreads at the workplace. Additionally, many studies have shown that productivity is not an individual factor but a social one: in any study on epidemic responses this social factor has to be taken into account. The barrier to addressing this problem has been the lack of data on the interaction and mobility patterns of people in the workplace. We have created a wearable Sociometric Badge that senses interactions between individuals using an infra-red (IR) transceiver and proximity using a radio transmitter. Using the data from the Sociometric Badges, we are able to simulate diseases spreading through face-to-face interactions with realistic epidemiological parameters. In this paper we construct a curve trading off productivity with epidemic potential. We are able to take into account impacts on productivity that arise from social factors, such as interaction diversity and density, wh...

  3. Genomic Resources for Cancer Epidemiology

    This page provides links to research resources, complied by the Epidemiology and Genomics Research Program, that may be of interest to genetic epidemiologists conducting cancer research, but is not exhaustive.

  4. Metabolomics and Epidemiology Working Group

    The Metabolomics and Epidemiology (MetEpi) Working Group promotes metabolomics analyses in population-based studies, as well as advancement in the field of metabolomics for broader biomedical and public health research.

  5. Sample Cancer Epidemiology Grant Applications

    The National Cancer Institute frequently receives questions from investigators for examples of successfully funded grant applications. Several investigators agreed to let the Epidemiology and Genomics Research Program post excerpts of their grant applications online.

  6. Structural equation modeling in epidemiology

    Leila Denise Alves Ferreira Amorim

    2010-12-01

    Full Text Available Structural equation modeling (SEM is an important statistical tool for evaluating complex relations in several research areas. In epidemiology, the use and discussion of SEM have been limited thus far. This article presents basic principles and concepts in SEM, including an application using epidemiological data analysis from a study on the determinants of cognitive development in young children, considering constructs related to organization of the child's home environment, parenting style, and the child's health status. The relations between the constructs and cognitive development were measured. The results showed a positive association between psychosocial stimulus at home and cognitive development in young children. The article presents the contributions by SEM to epidemiology, highlighting the need for an a priori theoretical model for improving the study of epidemiological questions from a new perspective.

  7. Epidemiology studies in critical care

    Martin, Greg

    2006-01-01

    Epidemiology studies are an essential part of clinical research, often forming the foundation for studies ranked more highly in the hierarchy of evidence-based medicine. Studies of sepsis to date have been conducted on local, regional, national and international scales, with the majority conducted in the past 5 years. Longitudinal epidemiology studies convey an important additional aspect of the healthcare burden from disease, and may additionally serve to compare the effectiveness and effici...

  8. Molecular Epidemiology and Air Pollution

    Rössner ml., Pavel; Binková, B.; Rössnerová, Andrea; Šrám, Radim

    Rieka: InTech, 2015 - (Nejadkoorki, F.), s. 609-643 ISBN 978-953-51-2180-0 R&D Projects: GA ČR GA13-13458S Institutional support: RVO:68378041 Keywords : molecular epidemiology * biomarkers * human populations * in vitro studies Subject RIV: DN - Health Impact of the Environment Quality http://www.intechopen.com/books/current-air-quality-issues/molecular-epidemiology-and-air- pollution

  9. Epidemiologia da insônia Epidemiology of the insomnia

    José Carlos Souza

    2004-04-01

    Full Text Available Os autores fizeram uma ampla revisão da literatura científica mundial sobre a epidemiologia da insônia, o mais prevalente dos distúrbios do sono. Foi feito um levantamento bibliográfico, no período de janeiro de 2002 a novembro de 2003, das publicações dos últimos 30 anos, nos bancos de dados MEDLINE e LILACS, sobre a definição e prevalência da insônia, além de suas conseqüências socioeconômicas. As palavras-chaves pesquisadas foram: distúrbio de iniciar o sono, distúrbio de manutenção do sono, distúrbio do despertar precoce, insônia, distúrbios do sono, prevalência da insônia, conseqüências da insônia. Observou-se uma grande variação dos critérios de definição da insônia, dos desenhos metodológicos e dos resultados dos estudos epidemiológicos, o que prejudicou as comparações dos dados das várias pesquisas. As futuras linhas de pesquisa sobre a epidemiologia da insônia devem se embasar em um consenso sobre sua definição e critérios metodológicos mais bem-definidos.A vast literature review on the insomnia epidemiology, the most common sleep disorder, using MEDLINE and LILACS last 30 years of data, was performed from January 2002 to November 2003. The key-words were: sleep initiation disorders, sleep maintenance disorders, early awakening disorder, insomnia, sleep disorders, insomnia prevalence, insomnia consequences. Several insomnia definition criteria and epidemiology researches methods, with data comparison difficulties, were noticed. In the future it will be necessary similar insomnia definition and epidemiology studies criteria.

  10. Epidemiological characteristics of autism spectrum disorder in Songjiang district ,Shanghai%上海市松江区幼儿孤独谱系障碍流行病学特征调查

    陆爱军; 王永飞; 姜凌霄; 王永强

    2016-01-01

    目的 了解上海市松江区公立幼儿园孤独谱系障碍(ASD)的流行现况.方法 以上海市松江区教育主管部门登记在册的33所公立幼儿园的幼儿作为调查对象,采用克氏孤独症行为量表和社会交往问卷进行筛查,对于筛查阳性者由儿少精神科医生根据美国精神疾病诊断与统计手册第五版(DSM-5)进行诊断.结果 共5704名儿童接受筛查,平均年龄(5.3±0.7)岁,其中男性2920名(51.2%),女性2784名(48.8%).6名儿童被诊断为ASD,男女比为5:1,时点患病率为1.05‰,年龄4.1~6.1岁,平均5.0岁.3名患儿的孕期及出生时存在高危因素.结论 上海市松江区公立幼儿园ASD患病率低于国内外报道,孕期保健应重视相关高危因素.%Objective To explore the prevalence of autism spectrum disorder (ASD) in public kin-dergartens in Songjiang District ,Shanghai.Methods Totals of 33 public kindergartens registered in the competent department of education in Songjiang District ,Shanghai were surveyed.Autism Behavior Scale and Social Communication Questionnaire were used to assess the children.For positive people ,the diagnose was made by psychiatrists according to the American psychiatric diagnosis and statistical analy-sis of manual ,5th edition (DSM -5).Results A total of 5704 children received screening ,the average age was (5.3 ± 0.7) years.Males (2920) accounted for 51.2% and females (2784) accounted for 48.8%.Six children were diagnosed with ASD ,ratio of male vs female was 5:1;point prevalence was 1.05‰ ,aged 4.1-6.1 years ,average age was 5.0 years.Three children were with high risk factors of pregnancy and birth.Conclusions The prevalence of ASD in public kindergartens in Songjiang District , Shanghai is lower than reports at home and abroad.Related risk factors should be concerned in prenatal care.

  11. 乌鲁木齐市大学生颞下颌关节紊乱病的流行病学调查分析%Study on epidemiological investigation of temporomandibular disorders among undergraduates in Urumqi

    卢冉; 姚志涛; 昆得孜·杜肯; 阿迪力江·赛买提; 阿地力·莫明

    2016-01-01

    目的:了解乌鲁木齐市大学生颞下颌关节紊乱病(TMD)的患病情况及口腔卫生保健意识,为针对性进行TMD教育及口腔保健预防工作提供理论依据。方法:对1223名乌鲁木齐市大学生进行颞下颌关节、口腔检查后根据Helkimo指数进行分析,包括既往及临床检查功能紊乱指数,评估TMD与民族、性别、学校、年级的关系,以及主要症状和不良习惯等。结果:患病率为51.10%,TMD的患病率在学校、民族间差异有统计学意义(P<0.05);精神心理因素、大张口与TMD的发生呈正相关(P<0.01);在TMD症状中,关节弹响发生率最高(69.12%);大学生对口腔卫生保健、TMD认知水平较低。结论:精神因素是TMD发生的决定因素,有必要提高大学生对TMD及口腔卫生保健的认知。%Objective To study the prevalence of temporomandibular disorders (TMD) and awareness of oral health among undergraduates in Urumqi is to provide theoretical basis for TMD education and prevention of orally health care.Methods A sample of 1223 students was randomly selected from ifve universities in Urumqi.The subjects were adopted temporomandibular and oral inspection .we take analysis to the result according Helkimo that comprised history and clinical examination dysfunction index. To evaluate the relationship between TMD and nationality, gender, school, grade, and the main symptoms and bad habits.Results The morbility rate of TMD was 51.10%,and the difference of morbility between universities and nations (P<0.05)had statistically significant. Psychological factor and opening of the jaw were positively related to the TMD(P<0.01). Clicking of joint has higher prevalence in TMD symptoms.The college students’ knowledge of TMD and oral health was poor.Conclusion Mental factor is the decisive factor in the occurrence of TMD .It is necessary to improve the cognition of college students on TMD and oral health care.

  12. Course and cognitive outcome in major affective disorder.

    Kessing, Lars Vedel

    2015-11-01

    Knowledge of the course and outcome of major affective illness has clinical as well as theoretical implications. In understanding the pathophysiology of the major affective disorders, an essential question in the interplay between biological, psychological and social factors is whether the individual is changed biologically by experiencing an affective episode or not. A biological change may be reflected in a changed risk of experiencing new episodes and changed chances of recovery from these episodes for the individual, and may possibly also be reflected in persisting altered cognitive function as an expression of brain function affected during a longer period. Previous studies of the course of affective episodes are flawed by a number of drawbacks such as various definitions of recovery and recurrence, various kinds of bias and confounders, low statistical power, and statistical analyses conducted without survival models and without paying attention to diagnostic instability or the individual heterogeneity of the course of episodes. Totally, these drawbacks and pitfalls affect the results of previous studies in unpredictable ways and make it hazardous to draw conclusions about the effect of prior affective episodes on the subsequent course of unipolar and bipolar disorder. The present thesis avoided most of these pitfalls or adjusted for them in analyses of hospital data from the Danish Psychiatric Central Register, collected nationwide from 1971 to 1993. Hospitalisation was used as an expression of an affective episode. On average, a progressive course with increasing risk of recurrence with every new episode was found for unipolar and bipolar affective disorders. Initially, the two types of disorders followed markedly different courses, but later in the course of the illness the risk of recurrence was the same for the two disorders. However, analyses with frailty models revealed that for unipolar men, this progressive course was due to a subgroup of patients

  13. Cognitive Therapy for Adjustment Disorder in Cancer Patients

    Schuyler, Dean

    2004-01-01

    A DIAGNOSIS OF CANCER INTERRUPTS THE LIFE OF A PATIENT AND HIS OR HER FAMILY. Cancer treatment often entails continued investigation and therapy that typically has side effects and offers the repeated warning to be vigilant. Cancer is often a life-threatening illness. The field of psycho-oncology is well established, and clinical oncologists often have a good awareness of the psychological challenges cancer poses to their patients. Despite the nature of the stressor, it is important to note t...

  14. Shift work disorder in nurses--assessment, prevalence and related health problems.

    Elisabeth Flo

    Full Text Available BACKGROUND: This study investigates the prevalence of symptoms of shift work disorder in a sample of nurses, and its association to individual, health and work variables. METHODOLOGY/PRINCIPAL FINDINGS: We investigated three different shift work disorder assessment procedures all based on current diagnostic criteria and employing symptom based questions. Crude and adjusted logistic regression analyses were performed with symptoms of shift work disorder as the dependent variable. Participants (n = 1968 reported age, gender, work schedule, commuting time, weekly work hours, children in household, number of nights and number of shifts separated by less than 11 hours worked the last year, use of bright light therapy, melatonin and sleep medication, and completed the Bergen Insomnia Scale, Epworth Sleepiness Scale, Global Sleep Assessment Questionnaire, Diurnal Scale, Revised Circadian Type Inventory, Dispositional Resilience (Hardiness Scale--Revised, Fatigue Questionnaire, questions about alcohol and caffeine consumption, as well as the Hospital Anxiety and Depression Scale. CONCLUSIONS/SIGNIFICANCE: Prevalence rates of symptoms of shift work disorder varied from 32.4-37.6% depending on the assessment method and from 4.8-44.3% depending on the work schedule. Associations were found between symptoms of shift work disorder and age, gender, circadian type, night work, number of shifts separated by less than 11 hours and number of nights worked the last year, insomnia and anxiety. The different assessment procedures yielded similar results (prevalence and logistic regression analyses. The prevalence of symptoms indicative of shift work disorder was high. We argue that three symptom-based questions used in the present study adequately assess shift work disorder in epidemiological studies.

  15. [Opportunity and challenge on molecular epidemiology].

    Duan, G C; Chen, S Y

    2016-08-10

    Molecular epidemiology, a branch of epidemiology, combines the theories and methods, both in epidemiology and molecular biology. Molecular epidemiology mainly focuses on biological markers, describing the distribution, occurrence, development and prognosis of diseases at the molecular level. The completion of Human Genome Project and rapid development of Precision Medicine and Big Data not only offer the new development opportunities but also bring about a higher demand and new challenge for molecular epidemiology. PMID:27539332

  16. Association between anxiety and hypertension: a systematic review and meta-analysis of epidemiological studies

    Pan Y

    2015-04-01

    Full Text Available Yu Pan,1,2,* Wenpeng Cai,1,* Qi Cheng,3,* Wei Dong,1 Ting An,4 Jin Yan1 1Department of Psychology and Mental Health, Second Military Medical University, Shanghai, 2Department of Psychology, Peoples Liberation Army General Hospital, Beijing, 3Department of Child and Adolescent Behavioral Medicine, The 102 Hospital of PLA, Changzhou, 4Department of Internal Medicine, The PLA Second Artillery Force General Hospital, Beijing, People’s Republic of China *These authors contributed equally to this work Background: Epidemiological studies have repeatedly investigated the association between anxiety and hypertension. However, the results have been inconsistent. This study aimed to summarize the current evidence from cross-sectional and prospective studies that evaluated this association. Methods: Seven common databases were searched for articles published up to November 2014. Cross-sectional and prospective studies that reported an association between the two conditions in adults were included. Data on prevalence, incidence, unadjusted or adjusted odds ratios or hazard ratios, and 95% confidence intervals (CIs were extracted or calculated by the authors. The pooled odds ratio was calculated separately for cross-sectional and prospective studies using random-effects models. The Q test and I2 statistic was used to assess heterogeneity. A funnel plot and modified Egger linear regression test were used to estimate publication bias. Results: The search yielded 13 cross-sectional studies (n=151,389, and the final pooled odds ratio was 1.18 (95% CI 1.02–1.37; PQ<0.001; I2=84.9%. Eight prospective studies with a total sample size of 80,146 and 2,394 hypertension case subjects, and the pooled adjusted hazard ratio was 1.55 (95% CI 1.24–1.94; PQ<0.001; I2=84.6%. The meta-regression showed that location, diagnostic criteria for anxiety, age, sex, sample size, year of publication, quality, and years of follow-up (for prospective study were not

  17. Epidemiology of juvenile violence.

    Farrington, D P; Loeber, R

    2000-10-01

    It is difficult to review the epidemiology of juvenile violence because few studies focus specifically on this topic as opposed to childhood aggression or delinquency in general. More research is needed specifically on juvenile violence, which is generally measured using official records or self-reports. Self-report research shows that a substantial fraction of the male juvenile population commits violence, and that very few violent acts are followed by arrests or convictions. Racial differences in violence may be explainable by reference to racial differences in community contexts. There is a great deal of versatility in juvenile violence. Juveniles who commit one type of violent offense also tend to commit other types and nonviolent offenses. Violent offenders tend to be persistent or frequent offenders, and there is little difference between violent offenders and nonviolent but equally frequent offenders. Nevertheless, there is some degree of specialization in violence. More research is needed to investigate whether risk factors exist for violence that are not risk factors for serious nonviolent delinquency (e.g., biologic factors). Violent juveniles tend to have co-occurring problems such as victimization, substance abuse, and school failure. Often, they might be described as multiple-problem youth. There is considerable continuity from childhood aggression to juvenile violence. An early age of onset of violence predicts a large number of violent offenses. The major long-term risk factors for juvenile violence are individual (high impulsiveness and low intelligence, possibly linked to the executive functions of the brain), family (poor supervision, harsh discipline, child physical abuse, a violent parent, large family size, poverty, a broken family), peer delinquency, gang membership, urban residence, and living in a high-crime neighborhood (characterized by gangs, guns, and drugs in the United States). More research is needed on interactions among risk factors

  18. Change in binge eating and binge eating disorder associated with migration from Mexico to the U.S.

    Swanson, Sonja A; Saito, Naomi; Borges, Guilherme; Benjet, Corina; Aguilar-Gaxiola, Sergio; Medina-Mora, Maria Elena; Breslau, Joshua

    2012-01-01

    Exposure to Western popular culture is hypothesized to increase risk for eating disorders. This study tests this hypothesis with respect to the proposed diagnosis of binge eating disorder (BED) in an epidemiological sample of people of Mexican origin in Mexico and the U.S. Data come from the Mexico National Comorbidity Survey, National Comorbidity Survey Replication, and National Latino and Asian American Survey (N = 2268). Diagnoses were assessed with the WMH-CIDI. Six groups were compared: Mexicans with no migrant family members, Mexicans with at least one migrant family member, Mexican return-migrants, Mexican-born migrants in the U.S., and two successive generations of Mexican-Americans in the U.S. The lifetime prevalence of BED was 1.6% in Mexico and 2.2% among Mexican-Americans. Compared with Mexicans in families with migrants, risk for BED was higher in US-born Mexican-Americans with two U.S.-born parents (aHR = 2.58, 95% CI 1.12-5.93). This effect was attenuated by 24% (aHR = 1.97, 95% CI 0.84-4.62) with adjustment for prior-onset depressive or anxiety disorder. Adjustment for prior-onset conduct disorder increased the magnitude of association (aHR = 2.75, 95% CI 1.22-6.20). A similar pattern was observed for binge eating. Among respondents reporting binge eating, onset in the U.S. (vs. Mexico) was not associated with prevalence of further eating disorder symptoms. Migration from Mexico to the U.S. is associated with an increased risk for BED that may be partially attributable to non-specific influences on internalizing disorders. Among respondents reporting binge eating in either country, similar levels of further symptoms were endorsed, suggesting some cross-cultural generalizability of criteria. PMID:22070904

  19. Epidemiological Investigation of Post-traumatic Stress Disorder in Military Personnel after Military Operation%军人军事行动创伤后应激障碍的流行病学调查

    卢家春; 呼永河; 王文春; 陈喆思; 张安仁; 卢豪; 江玥; 袁青; 庞日朝; 王倩

    2016-01-01

    Objective To investigate the occurrence of post-traumatic stress disorder (PTSD) in military personnel 3 months after a military exercise and the related factors. Methods Structured questionnaire and psychological scale assessment were applied to 690 sol-diers 3 months after a military exercise in relative factor investigation during the period from April, 2011 to July, 2014;for those with high cut-off points in the primary screen by PTSD checklist-military version (PCL-M),a one-to-one interview was carried out by psychia-trists, and the diagnosis of PTSD was confirmed based on DSM-IV;logistic regression analysis was made to the materials with the soft-ware SPSS13.0. Results 690 soldiers were enrolled in the investigation while 637 questionnaires were effective, and there were 30 cases of confirmed diagnosis of PTSD, taking up 4.71%;positive individual psychological symptoms, including somatization, obsessive-com-pulsive, depression, anxiety, interpersonal relationship, hostility, fright, paranoid idea and psychoticism, were statistically different from those of Chinese male norm (P<0.05);the factors impacting mental health were:only child, living in cities and towns, low service satis-faction, failing to get economic help when having difficulties, injury, too heavy exercise task, dissatisfied with the superior instruction;stressful events had no impact on individual character in a short time (P<0.05). Conclusions The occurrence of PTSD in military person-nel 3 months after military exercises is higher than that in norm;it is necessary to strengthen the psychological protection and crisis inter-vention.%目的:了解某部参加军事演习的官兵3个月后创伤后应激障碍(PTSD)的患病率及相关因素。方法2011年4月—2014年7月通过结构式问卷调查和心理量表测评对某部参加军事演习3个月的690名官兵进行相关因素调查。PTSD诊断采用PTSD筛查量表-军人版(PCL-M)进行初筛,再由精神科医师依

  20. Epidemiological survey of post-traumatic stress disorder in the victims of Lushan earthquake%芦山地震受灾人群创伤后应激障碍的流行病学调查

    邱昌建; 黄明金; 黄国平; 谭友果; 张英辉; 袁茵; 余成民; 罗明; 周波

    2015-01-01

    目的 调查芦山地震受灾人群PTSD的患病率及其影响因素.方法 采用横断面调查,在四川省雅安市芦山县、宝兴县两地分层随机抽取1110名成年被调查者,使用自编问卷采集一般人口学资料、芦山地震受灾情况以及芦山地震、汶川地震对被调查者影响的比较等,PTSD筛查量表平民版(PTSD Check List-Civilian Version,PCL-C)筛查被调查者对芦山地震的应激反应程度,MINI-自杀风险评估其自杀风险.PCL-C>38分者由精神科医师采用MINI中文版中的PTSD章节诊断其是否患有PTSD.采用线性回归分析方法对PTSD的影响因素进行相关分析.结果 998名被调查者纳入分析,其中男372名(37.27%,372/998),女626名(62.73%,626/998).PCL-C>38分者251名(25.15%,251/998),PTSD患者24例,PTSD患病率2.40%(24/998).自杀高风险者11名(1.10%,11/998).回归分析显示,PCL-C总分与女性(β=-2.041)、家庭低收入(β=-3.870)、地震中亲属遇难(β=0.164)、朋友遇难(β=-0.059)、地震中被掩埋(β=-14.335)、受伤(β=0.495)等因素相关(均P<0.05).女性(OR=4.304)、地震中被掩埋(OR=15.688)是罹患PTSD的危险因素(均P<0.05).家庭低收入(OR=3.147)、罹患PTSD (OR=25.101)是自杀高风险的危险因素(均P<0.05).结论 5年内连续2次遭受地震创伤的受灾人群中PTSD的患病率并不高,女性及在地震中自身生命受威胁是罹患PTSD的危险因素,应有针对性地进行干预.%Objective To investigate the prevalence and influence factors of post-traumatic stress disorder (PTSD) in people experiencing the Lushan 4.20 earthquake in 2013.Methods By stratified random sampling,a cross-sectional survey was conducted among 1 110 adult victims from the county of Lushan and Baoxing three months after the earthquake.Self-made questionnaire was adopted to collect the demographic data and the general situation of the disaster and compare with the situation of Wenchuan 5.12 earthquake.The scale of

  1. TMJ Disorders

    ... referred Sally and her parents to a local dentist who specialized in jaw disorders. After examining Sally ... having symptoms of a TMJ disorder, let your dentist know. The earlier a TMJ disorder is diagnosed ...

  2. Mathematics disorder

    Mathematics disorder is a condition in which a child's math ability is far below normal for their ... Children who have mathematics disorder have trouble with simple ... disorder may appear with: Developmental coordination ...

  3. Genetic Disorders

    ... This can cause a medical condition called a genetic disorder. You can inherit a gene mutation from ... during your lifetime. There are three types of genetic disorders: Single-gene disorders, where a mutation affects ...

  4. Adjustable Induction-Heating Coil

    Ellis, Rod; Bartolotta, Paul

    1990-01-01

    Improved design for induction-heating work coil facilitates optimization of heating in different metal specimens. Three segments adjusted independently to obtain desired distribution of temperature. Reduces time needed to achieve required temperature profiles.

  5. Adjustment to Spinal Cord Injury

    ... may need to work to help with family finances. All of the changes that they face can ... 2000). Goal instability and adjustment to physical disability. Journal of Counseling Psychology, 47(2). 251-265. This ...

  6. Mood disorders in childhood and adolescence

    Thiago Botter Maio Rocha

    2013-01-01

    Full Text Available The identification and treatment of mood disorders in children and adolescents has grown over the last decades. Major depression is one of the most common and debilitating disorders worldwide, imposing a massive burden to the youth population. Bipolar disorder is being increasingly recognized as having its roots early in life, and its presentation during childhood and adolescence has been submitted to extensive research. This review aims to highlight clinical aspects of the current knowledge on mood disorders in the pediatric population, presenting updated information on epidemiology, diagnostic procedures, and management strategies. Limitations of available evidence and future directions of research in the field are also discussed.

  7. Adjustment techniques for experimental data

    To carry through numerically the different adjustment of experimental data planned by National Institute of Nuclear Research investigators. It is presented the different adjustment techniques of experimental data which are fundamentally for: linear least squares, non linear with restrictions. Methodology: Lineal least squares - Orthogonal decomposition via Householder reflections. No lineal - Method of general lowering and quasi Newton; Levenberg-Marquardt modified - More version. No lineal with restrictions - Quadratic sequential programming method (In process). (Author)

  8. Panic disorder

    ... Anxiety disorder - panic attacks References American Psychiatric Association. Diagnostic and statistical manual of mental disorders . 5th ed. Arlington, VA: American Psychiatric Publishing. 2013. ...

  9. Phonological disorder

    Articulation disorder; Developmental articulation disorder; Speech distortion; Sound distortion ... unknown. Close relatives may have had speech and language problems. ... sounds. These changes may include cleft palate and problems ...

  10. CLINICAL, EPIDEMIOLOGICAL AND MYCOLOGICA

    Ratheesh T

    2014-09-01

    Full Text Available BACKGROUND: Tinea versicolor is a chronic, mild, usually asymptomatic infection of the stratum corneum. The lesions are discrete or confluent and appear as discolored or hypo pigmented areas of the skin. The affected areas are located principally on the chest, abdomen, upper extremities and back. The etiologic agent is the lipophilic yeast Pityrosporum orbiculare, part of the normal flora of the human skin. This study is undertaken to know “clinical, patterns of the disease with respect to morphology and distribution, associated conditions and epidemiological factors like age, sex distribution and seasonal variation of the disease”. METHODS: Two hundred patients of tinea versicolor were selected. Patients belonging to the age group of above 10 years and below 60 years belonging to both sexes were selected and included in the study group after taking consent. A detailed history was taken with particular reference to onset, duration, symptoms and treatment taken and were recorded. Factors like – seasonal variation, family history and presence of any associated illnesses was also noted. A thorough clinical examination was done with reference to the location, the color, the extent of the lesions, the margins, the type of lesions and the details were recorded. Potassium hydroxide (KOH examination and Wood’s lamp examination were done in all the patients before therapy. RESULTS: Out of 200 patients, majority of them belong to 2nd and 3rd decade of life (72%. The Male: Female ratio was 1.5:1. There was a family history of 16%. The trunk was the most common site involved. Majority of the patients had exacerbation in summer. The most common associated dermatoses were acne vulgaris, immunosuppression and infections. INTERPRETATION AND CONCLUSION: Tinea versicolor is a disease of worldwide distribution, although it is significantly more common in humid and tropical climates. The true incidence cannot be estimated precisely because the disease is

  11. Association of Sleep Disordered Breathing with Mono-Symptomatic Nocturnal Enuresis: A Study among School Children of Central India

    Pakhare, Abhijit P.; Goyal, Abhishek; P, Aswin; Dhingra, Bhavna; Tamaria, K. C.

    2016-01-01

    Objective To study the prevalence of primary monosymptopomatic nocturnal enuresis (PMNE) in children aged 5–10 year and to find its association with sleep disordered breathing (SDB) by using a 22 item pediatric sleep related breathing disorder (SRBD) scale. Methods This was a school based cross sectional epidemiological study from July 2015 to November 2015. A questionnaire seeking information on socio-demographic variables, nocturnal enuresis (NE) frequency, school performance and a validated 22 item pediatric sleep related breathing disorder scale (SRBDs) was distributed to 1820 pupils in three primary schools. Results A total of 1528(83.95%) questionnaires were retrieved. Out of 1528 forms, 182(11.9%) forms were incomplete for requested information and hence 1346 (73.9%) questionnaires were finally analyzed. The prevalence of NE was found to be 12.7% (95% CI; 11–14.6), whereas prevalence of primary nocturnal enuresis (PMNE) was 8.2% (95% CI; 7.1–10.1). SRBD scale score >0.33 (adjusted OR: 2.87; 95%CI: 1.67–4.92), paternal history of enuresis in childhood (adjusted OR:4.96; 95% CI: 2.36–10.45), and inappropriate toilet training (adjusted OR: 1.64; 95% CI: 1.01–2.66) were independently associated with PMNE. Conclusion Sleep disordered breathing, inappropriate toilet training and a history of childhood NE in father were found to be significant risk factors for PMNE in the present study. Thus, these findings suggest that it is imperative to rule out SDB in PMNE patients as they may require different therapeutic interventions. PMID:27191620

  12. Environmental epidemiology: challenges and opportunities.

    Pekkanen, J; Pearce, N

    2001-01-01

    Epidemiology is struggling increasingly with problems with correlated exposures and small relative risks. As a consequence, some scholars have strongly emphasized molecular epidemiology, whereas others have argued for the importance of the population context and the reintegration of epidemiology into public health. Environmental epidemiology has several unique features that make these debates especially pertinent to it. The very large number of environmental exposures require prioritization, and the relative risks are usually very low. Furthermore, many environmental exposures can be addressed only by comparing populations rather than individuals, and the disruption of both local and global ecosystems requires us to develop new methods of study design. The population context is also very important to consider in risk management decisions because of the involuntary nature of most environmental exposures and the diversity of possible outcomes, both health- and nonhealth-related. Studies at the individual or molecular level tend to focus the research hypotheses and subsequent interventions at that level, even when research and interventions at other levels may be more appropriate. Thus, only by starting from the population and ecosystem levels can we ensure that these are given appropriate consideration. Although better research is needed at all levels, it is crucially important to choose the most appropriate level, or levels, of research for a particular problem. Only by conducting research at all these levels and by developing further methods to combine evidence from these different levels can we hope to address the challenges facing environmental epidemiology today. PMID:11171517

  13. Epidemiology of fibromuscular dysplasia: A review of the literature.

    Shivapour, Daniel M; Erwin, Phillip; Kim, Esther Sh

    2016-08-01

    Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory disease of medium sized arteries that has been described in multiple anatomic territories with a wide variety of manifestations (e.g. beading, stenosis, occlusion, aneurysm, or dissection). While the first case of FMD is thought to have been described over 75 years ago, the causes, natural history, and epidemiology of FMD in the general population remain incompletely understood. This article reviews important historical and contemporary contributions to the FMD literature that inform our current understanding of the prevalence and epidemiology of this important disorder. A particular focus is given to studies which form the basis for FMD prevalence estimates. Prevalence estimates for renal FMD are derived from renal transplant donor studies and sub-studies of clinical trials of renal artery stenting; however, it is unclear how well these estimates generalize to the overall population as a whole. Newer data are emerging examining the genetic associations and environmental interactions with FMD. Significant contributions to the understanding of FMD have come from the United States Registry for Fibromuscular Dysplasia; however, many unanswered questions remain, and future studies are required to further characterize FMD epidemiology in general populations and advance our understanding of this important disorder. PMID:27067138

  14. The frequency of personality disorders in patients with gender identity disorder

    Meybodi, Azadeh Mazaheri; Hajebi, Ahmad; Jolfaei, Atefeh Ghanbari

    2014-01-01

    Background: Co-morbid psychiatric disorders affect prognosis, psychosocial adjustment and post-surgery satisfaction in patients with gender identity disorder. In this paper, we assessed the frequency of personality disorders in Iranian GID patients. Methods: Seventy- three patients requesting sex reassignment surgery (SRS) were recruited for this crosssectional study. Of the participants, 57.5% were biologically male and 42.5% were biologically female. They were assessed through the Millon Clinical Multiaxial Inventory II (MCMI- II). Results: The frequency of personality disorders was 81.4%. The most frequent personality disorder was narcissistic personality disorder (57.1%) and the least was borderline personality disorder. The average number of diagnoses was 3.00 per patient. Conclusion: The findings of this study revealed that the prevalence of personality disorders was higher among the participants, and the most frequent personality disorder was narcissistic personality disorder (57.1%), and borderline personality disorder was less common among the studied patients. PMID:25664291

  15. The relationship of obsessive-compulsive disorder to putative spectrum disorders: results from an Indian study.

    Jaisoorya, T S; Reddy, Y C Janardhan; Srinath, S

    2003-01-01

    The relationship between obsessive-compulsive disorder (OCD) and putative obsessive-compulsive (OC) spectrum disorders is unclear. This study investigates the prevalence of putative OC spectrum disorders in OCD subjects in a controlled clinical design. The putative OC spectrum disorders studied included somatoform disorders (body dysmorphic disorder [BDD] and hypochondriasis), eating disorders, tic disorders (e.g., Tourette's syndrome [TS]), and impulse control disorders (e.g., trichotillomania). Only those disorders that are commonly noted to be possibly related to OCD are studied. Included in this study were 231 subjects with a diagnosis of OCD according to DSM-IV criteria and 200 controls who were not screened for psychiatric morbidity. The subjects and controls were assessed in detail by extensive clinical and semistructured interviews by expert clinical psychiatrists. The lifetime diagnoses were made by consensus of two psychiatrists. Prevalence of tic disorders, hypochondriasis, BDD, and trichotillomania was significantly greater in OCD subjects compared to controls. However, the prevalence of sexual compulsions, pathological gambling, eating disorders, and depersonalization disorder was not greater in the OCD subjects compared to controls. The findings of this comorbidity study suggest that tic disorders, hypochondriasis, BDD, and trichotillomania are perhaps part of the OC spectrum disorders. There is a need to evaluate evidence from other sources such as epidemiological, neurobiological, and family studies to further our understanding of the concept of OC spectrum disorders. PMID:12923710

  16. Suicide during Perinatal Period: Epidemiology, Risk Factors, and Clinical Correlates.

    Orsolini, Laura; Valchera, Alessandro; Vecchiotti, Roberta; Tomasetti, Carmine; Iasevoli, Felice; Fornaro, Michele; De Berardis, Domenico; Perna, Giampaolo; Pompili, Maurizio; Bellantuono, Cesario

    2016-01-01

    Perinatal period may pose a great challenge for the clinical management and treatment of psychiatric disorders in women. In fact, several mental illnesses can arise during pregnancy and/or following childbirth. Suicide has been considered a relatively rare event during the perinatal period. However, in some mental disorders (i.e., postpartum depression, bipolar disorder, postpartum psychosis, etc.) have been reported a higher risk of suicidal ideation, suicide attempt, or suicide. Therefore, a complete screening of mothers' mental health should also take into account thoughts of suicide and thoughts about harming infants as well. Clinicians should carefully monitor and early identify related clinical manifestations, potential risk factors, and alarm symptoms related to suicide. The present paper aims at providing a focused review about epidemiological data, risk factors, and an overview about the main clinical correlates associated with the suicidal behavior during the pregnancy and postpartum period. Practical recommendations have been provided as well. PMID:27570512

  17. Comorbidity of eating disorder and alcohol dependency

    Vuković Olivera

    2007-01-01

    Full Text Available Introduction. Epidemiological studies suggest that a high prevalence of alcohol addiction exists in female patients diagnosed with eating disorder in comparison to general population. For the purpose of explanation of the relationship of these disorders many conceptual models have been proposed. Case report. We presented a female patient displaying a comorbidity of eating disorder and alcohol dependency. We analyzed phenomenological similarities, personal characteristics and bio-psychological predisposition in order to ensure better understanding of the nature of the correlation of the two mentioned disorders. Conclusion. Even though, these days we find the synonym for eating disorders in the phrase "food addiction", it is impossible to categorize such a complex group of disorders to an addictive process. Moreover, we could assume that there exists a common psychobiological vulnerability which predisposes the development of one and/or the other disorder. To date knowledge has a significant implication for the development of new strategy in treating this comorbidity.

  18. Epidemiology of Enterovirus D68 in Ontario.

    Adriana Peci

    Full Text Available In August 2014, children's hospitals in Kansas City, Missouri and Chicago, Illinois notified the Centers for Disease Control and Prevention (CDC about increased numbers of pediatric patients hospitalized with severe respiratory illness (SRI. In response to CDC reports, Public Health Ontario Laboratories (PHOL launched an investigation of patients being tested for enterovirus D-68 (EV-D68 in Ontario, Canada. The purpose of this investigation was to enhance our understanding of EV-D68 epidemiology and clinical features. Data for this study included specimens submitted for EV-D68 testing at PHOL from September 1, 2014 to October 31, 2014. Comparisons were made between patients who tested positive for the virus (cases and those testing negative (controls. EV-D68 was identified in 153/907 (16.8% of patients tested. In the logistic regression model adjusting for age, sex, setting and time to specimen collection, individuals younger than 20 years of age were more likely to be diagnosed with EV-D68 compared to those 20 and over, with peak positivity at ages 5-9 years. Cases were not more likely to be hospitalized than controls. Cases were more likely to be identified in September than October (OR 8.07; 95% CI 5.15 to 12.64. Routine viral culture and multiplex PCR were inadequate methods to identify EV-D68 due to poor sensitivity and inability to differentiate EV-D68 from other enterovirus serotypes or rhinovirus. Testing for EV-D68 in Ontario from July to December, 2014 detected the presence of EV-D68 virus among young children during September-October, 2014, with most cases detected in September. There was no difference in hospitalization status between cases and controls. In order to better understand the epidemiology of this virus, surveillance for EV-D68 should include testing of symptomatic individuals from all treatment settings and patient age groups, with collection and analysis of comprehensive clinical and epidemiological data.

  19. Epidemiology of Enterovirus D68 in Ontario.

    Peci, Adriana; Winter, Anne-Luise; Warshawsky, Bryna; Booth, Tim F; Eshaghi, AliReza; Li, Aimin; Perusini, Stephen; Olsha, Romy; Marchand-Austin, Alex; Kristjanson, Erik; Gubbay, Jonathan B

    2015-01-01

    In August 2014, children's hospitals in Kansas City, Missouri and Chicago, Illinois notified the Centers for Disease Control and Prevention (CDC) about increased numbers of pediatric patients hospitalized with severe respiratory illness (SRI). In response to CDC reports, Public Health Ontario Laboratories (PHOL) launched an investigation of patients being tested for enterovirus D-68 (EV-D68) in Ontario, Canada. The purpose of this investigation was to enhance our understanding of EV-D68 epidemiology and clinical features. Data for this study included specimens submitted for EV-D68 testing at PHOL from September 1, 2014 to October 31, 2014. Comparisons were made between patients who tested positive for the virus (cases) and those testing negative (controls). EV-D68 was identified in 153/907 (16.8%) of patients tested. In the logistic regression model adjusting for age, sex, setting and time to specimen collection, individuals younger than 20 years of age were more likely to be diagnosed with EV-D68 compared to those 20 and over, with peak positivity at ages 5-9 years. Cases were not more likely to be hospitalized than controls. Cases were more likely to be identified in September than October (OR 8.07; 95% CI 5.15 to 12.64). Routine viral culture and multiplex PCR were inadequate methods to identify EV-D68 due to poor sensitivity and inability to differentiate EV-D68 from other enterovirus serotypes or rhinovirus. Testing for EV-D68 in Ontario from July to December, 2014 detected the presence of EV-D68 virus among young children during September-October, 2014, with most cases detected in September. There was no difference in hospitalization status between cases and controls. In order to better understand the epidemiology of this virus, surveillance for EV-D68 should include testing of symptomatic individuals from all treatment settings and patient age groups, with collection and analysis of comprehensive clinical and epidemiological data. PMID:26599365

  20. 7 CFR 251.7 - Formula adjustments.

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Formula adjustments. 251.7 Section 251.7 Agriculture... GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION THE EMERGENCY FOOD ASSISTANCE PROGRAM § 251.7 Formula adjustments. Formula adjustments. (a) Commodity adjustments. The Department will make annual adjustments...

  1. Panic Disorder and Women

    ... disorder. Other types of anxiety disorders include generalized anxiety disorder , obsessive compulsive disorder , social phobia , and post-traumatic stress disorders . Panic disorder affects women twice as often ...

  2. Viral marketing as epidemiological model

    Rodrigues, Helena Sofia

    2015-01-01

    In epidemiology, an epidemic is defined as the spread of an infectious disease to a large number of people in a given population within a short period of time. In the marketing context, a message is viral when it is broadly sent and received by the target market through person-to-person transmission. This specific marketing communication strategy is commonly referred as viral marketing. Due to this similarity between an epidemic and the viral marketing process and because the understanding of the critical factors to this communications strategy effectiveness remain largely unknown, the mathematical models in epidemiology are presented in this marketing specific field. In this paper, an epidemiological model SIR (Susceptible- Infected-Recovered) to study the effects of a viral marketing strategy is presented. It is made a comparison between the disease parameters and the marketing application, and simulations using the Matlab software are performed. Finally, some conclusions are given and their marketing impli...

  3. Epidemiology of idiopathic pulmonary fibrosis

    Ley B

    2013-11-01

    Full Text Available Brett Ley, Harold R Collard Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California San Francisco, San Francisco, California, USA Abstract: Idiopathic pulmonary fibrosis is a chronic fibrotic lung disease of unknown cause that occurs in adults and has a poor prognosis. Its epidemiology has been difficult to study because of its rarity and evolution in diagnostic and coding practices. Though uncommon, it is likely underappreciated both in terms of its occurrence (ie, incidence, prevalence and public health impact (ie, health care costs and resource utilization. Incidence and mortality appear to be on the rise, and prevalence is expected to increase with the aging population. Potential risk factors include occupational and environmental exposures, tobacco smoking, gastroesophageal reflux, and genetic factors. An accurate understanding of its epidemiology is important, especially as novel therapies are emerging. Keywords: idiopathic pulmonary fibrosis, epidemiology, incidence, prevalence, mortality, risk factors

  4. Epidemiología de campo y epidemiología social Field epidemiology and social epidemiology

    Javier Segura del Pozo

    2006-03-01

    Full Text Available Mediante la comparación de la epidemiología de campo y la epidemiología social, se pretende reflexionar sobre los imaginarios no explícitos que operan en ambos ámbitos, necesariamente convergentes, sobre los obstáculos de la práctica epidemiológica actual para alcanzar su función social y sobre la necesidad de cambiar las bases epistemológicas, metodológicas y prácticas que operan en la epidemiología, empezando por la formación del epidemiólogo de campo. La epidemiología de campo tiende a la acción sin marco teórico. La epidemiología social, por el contrario, tiende a los desarrollos teóricos (reflexión e investigación sobre los determinantes sociales alejados de la acción, debido a los limitantes para cambiar las políticas públicas. Otras diferencias se sitúan en el nivel de intervención (micro/macroespacios, el objeto de intervención (control del brote frente a control de las desigualdades y en la forma de articular la comunicación con la sociedad. Se asemejan en la preocupación por el método, la predominancia de una orientación positivista y condicionada por la estadística, aunque en proceso de cierta apertura epistemológica, la tensión experimentada entre relacionarse con un mundo virtual de bases de datos o con la sociedad real, su situación en la periferia del sistema político-social-institucional-profesional y por estar abocadas a la frustración profesional. Finalmente, se formulan 10 interrogantes a los epidemiólogos de campo sobre su práctica actual, a través de los cuales se podría evaluar si están realizando una epidemiología social, y se sugieren cambios para introducir en la formación y práctica del epidemiólogo.Comparing field epidemiology and social epidemiology, we pretend to think about the no explicit images and meanings operating in both necessary convergent fields, about the obstacles present in epidemiological practice to fulfil its social function and about the necessity of

  5. Prevalence of Mood Disorders in Iran

    Hamid Reza Pouretemad; Hamid Reza Naghavi; Hossein Malekafzali; Ahmad Ali Noorbala; Harutiun Davidian1; Ahmad Ghanizadeh; Mohammad-Reza Mohammadi; S. Abbas Bagheri Yazdi; Mehdi Rahgozar

    2006-01-01

    Objective:To study the prevalence and demographic characteristics of mood disorders among Iranian adults. Method: In this cross-sectional population-based epidemiological study (age > 18) in Iran, 25180 individuals were selected through a randomized cluster sampling method for a diagnosis using the Schedule for Affective Disorders and Schizophrenia (SADS). They were then interviewed at home by 250 trained clinical psychologists. Results: The estimated lifetime prevalence of Major Depressiv...

  6. Epidemiology of early-onset schizophrenia.

    Häfner, H; Nowotny, B

    1995-01-01

    A total of 232 (84%) first episodes of schizophrenia from our epidemiologically defined ABC sample (Age, Beginning and Course) were retrospectively assessed with regard to the onset and early course of the disorder. In a follow-up study a representative subgroup (n = 133) was prospectively examined in five cross sections over 3 years from first admission on. Population-based incidence rates for 5-year age groups comprising a range of adult patients who had been admitted with a first schizophrenic episode after age 20 years the prodromal phase, in 11% the psychotic prephase, began before that age. This demonstrates that schizophrenia often begins in an age period in which the social and cognitive development and brain maturation are still unfinished. Early-onset schizophrenias (schizophrenia-specific positive and negative syndromes in early-onset schizophrenia is comparable to that of higher age groups. However, neurotic syndromes, emotional disorders and conduct disorders are most frequent in younger patients, especially in young men. Paranoid syndromes seem to prevail in late-onset schizophrenia, whereas less differentiated positive syndromes, such as delusional mood, are more frequent in the youngest age group. An earlier onset of schizophrenia has more severe social consequences than onset in adults, because it interrupts the cognitive and social development at an earlier stage. The worse social course of schizophrenia in men compared with women cannot be related to a more severe symptomatology, but to the earlier age at onset and the impairment or stagnation of social ascent at an earlier stage of social and cognitive development. Social disability in the sense of an adaptation to the expectations of the social environment, as well as symptomatology during the further course of schizophrenia, show no major differences between the genders nor between the age groups. PMID:7654792

  7. The separation of adult separation anxiety disorder.

    Baldwin, David S; Gordon, Robert; Abelli, Marianna; Pini, Stefano

    2016-08-01

    The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) categorization of mental disorders places "separation anxiety disorder" within the broad group of anxiety disorders, and its diagnosis no longer rests on establishing an onset during childhood or adolescence. In previous editions of DSM, it was included within the disorders usually first diagnosed in infancy, childhood, or adolescence, with the requirement for an onset of symptoms before the age of 18 years: symptomatic adults could only receive a retrospective diagnosis, based on establishing this early onset. The new position of separation anxiety disorder is based upon the findings of epidemiological studies that revealed the unexpectedly high prevalence of the condition in adults, often in individuals with an onset of symptoms after the teenage years; its prominent place within the DSM-5 group of anxiety disorders should encourage further research into its epidemiology, etiology, and treatment. This review examines the clinical features and boundaries of the condition, and offers guidance on how it can be distinguished from other anxiety disorders and other mental disorders in which "separation anxiety" may be apparent. PMID:27503572

  8. Adolescents with ADHD: patterns of behavioral adjustment, academic functioning, and treatment utilization.

    Barkley, R A; Anastopoulos, A D; Guevremont, D C; Fletcher, K E

    1991-09-01

    Adolescents with attention deficit hyperactivity disorder (ADHD) were compared with a control group on a comprehensive assessment battery. More ADHD teenagers had oppositional defiant disorder (68%) and conduct disorder (39%) and were rated as more impaired in social competence, behavioral and emotional adjustment, and school performance by parents and teachers than control teens. The ADHD youths, however, rated themselves as better adjusted than did their parents and teachers, differing only from controls in depressive symptoms and antisocial acts. Poorer performances in verbal learning and vigilance and greater ADHD behaviors during a math task also distinguished the ADHD from control teenagers. PMID:1938790

  9. National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)—Wave 1 (2001–2002), and Wave 2 (2004–2005)

    U.S. Department of Health & Human Services — National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) was designed to assess the prevalence of alcohol use disorders (AUD) and their associated...

  10. Epidemiology, Molecular Epidemiology and Evolution of Bovine Respiratory Syncytial Virus

    Gilberto Vaughan

    2012-11-01

    Full Text Available The bovine respiratory syncytial virus (BRSV is an enveloped, negative sense, single-stranded RNA virus belonging to the pneumovirus genus within the family Paramyxoviridae. BRSV has been recognized as a major cause of respiratory disease in young calves since the early 1970s. The analysis of BRSV infection was originally hampered by its characteristic lability and poor growth in vitro. However, the advent of numerous immunological and molecular methods has facilitated the study of BRSV enormously. The knowledge gained from these studies has also provided the opportunity to develop safe, stable, attenuated virus vaccine candidates. Nonetheless, many aspects of the epidemiology, molecular epidemiology and evolution of the virus are still not fully understood. The natural course of infection is rather complex and further complicates diagnosis, treatment and the implementation of preventive measures aimed to control the disease. Therefore, understanding the mechanisms by which BRSV is able to establish infection is needed to prevent viral and disease spread. This review discusses important information regarding the epidemiology and molecular epidemiology of BRSV worldwide, and it highlights the importance of viral evolution in virus transmission.

  11. Extraintestinal manifestations of inflammatory bowel disease: epidemiology, diagnosis, and management

    Larsen, Signe; Bendtzen, Klaus; Nielsen, Ole Haagen

    2010-01-01

    Abstract Extraintestinal manifestations occur rather frequently in inflammatory bowel disease (IBD), e.g. ulcerative colitis (UC) and Crohn's disease (CD). The present paper provides an overview of the epidemiology, clinical characteristics, diagnostic process, and management of rheumatic...... the European Agency for the Evaluation of Medicinal Products (EMEA) and the US Food and Drug Administration (FDA) (cut-off date October 2009). The search terms 'Crohn's disease', 'inflammatory bowel disease', or 'ulcerative colitis' were combined with the terms 'adalimumab', 'anemia', 'arthritis...... evidence of treatment was difficult to obtain, and epidemiologic data on the rarer forms of extraintestinal manifestations are scarce. However, updates on the pathophysiology and treatment regimens are given for each of these disorders. This paper offers a current review of original research papers and...

  12. Mental illness and reduction of gun violence and suicide: bringing epidemiologic research to policy.

    Swanson, JW; McGinty, EE; Fazel, S; Mays, VM

    2015-01-01

    PURPOSE: This article describes epidemiologic evidence concerning risk of gun violence and suicide linked to psychiatric disorders, in contrast to media-fueled public perceptions of the dangerousness of mentally ill individuals, and evaluates effectiveness of policies and laws designed to prevent firearms injury and mortality associated with serious mental illnesses and substance use disorders. METHODS: Research concerning public attitudes toward persons with mental illness is reviewed and ju...

  13. Review of the prevalence and incidence of eating disorders

    Hoek, HW; van Hoeken, D

    2003-01-01

    Objective: To review the literature on the incidence and prevalence of eating disorders. Methods: We searched Medline using several key terms relating to epidemiology and eating disorders and we checked the reference lists of the articles that we found. Special attention has been paid to methodologi

  14. MCCB warm adjustment testing concept

    Erdei, Z.; Horgos, M.; Grib, A.; Preradović, D. M.; Rodic, V.

    2016-08-01

    This paper presents an experimental investigation in to operating of thermal protection device behavior from an MCCB (Molded Case Circuit Breaker). One of the main functions of the circuit breaker is to assure protection for the circuits where mounted in for possible overloads of the circuit. The tripping mechanism for the overload protection is based on a bimetal movement during a specific time frame. This movement needs to be controlled and as a solution to control this movement we choose the warm adjustment concept. This concept is meant to improve process capability control and final output. The warm adjustment device design will create a unique adjustment of the bimetal position for each individual breaker, determined when the testing current will flow thru a phase which needs to trip in a certain amount of time. This time is predetermined due to scientific calculation for all standard types of amperages and complies with the IEC 60497 standard requirements.

  15. Unravelling psychosis: psychosocial epidemiology, mechanism, and meaning.

    Bebbington, Paul

    2015-04-25

    This paper reviews a revolution in our understanding of psychosis over the last 20 years. To a major extent, this has resulted from a process of cross-fertilization between psychosocial epidemiology and cognitive behavior therapy for psychosis (CBT-p). This encouraged complementary strategies for the acquisition and analysis of data. These include the use of a range of dependent variables related to psychosis, and the exploitation of data from cross-sectional and longitudinal epidemiological surveys, virtual reality experiments, experience sampling methodology, and treatment trials. The key element is to investigate social and psychological measures in relation to each other. This research has confirmed the role of the external social world in the development and persistence of psychotic disorder. In addition, several psychological drivers of psychotic experiences have been identified. There is now persuasive evidence that the influence of social factors in psychosis is significantly mediated by non-psychotic symptoms, particularly mood symptoms and other attributes of affect such as insomnia. Psychotic symptoms are also driven by reasoning biases such as jumping to conclusions and belief inflexibility, though little is known about social influences on such biases. It is now clear that there are many routes to psychosis and that it takes many forms. Treatment of all kinds should take account of this: the dependence of CBT-p on a detailed initial formulation in terms of psychological processes and social influences is an example of the required flexibility. Individual mediators are now being targeted in specific forms of CBT-p, with good effect. This in turn corroborates the hypothesized role of non-psychotic symptoms in mediation, and attests to the power of the approaches described. PMID:26120255

  16. Environmental exposure measurement in cancer epidemiology

    2009-01-01

    Environmental exposures, used in the broadest sense of lifestyle, infections, radiation, natural and man-made chemicals and occupation, are a major cause of human cancer. However, the precise contribution of specific risk factors and their interaction, both with each other and with genotype, continues to be difficult to elucidate. This is partially due to limitations in accurately measuring exposure with the subsequent risk of misclassification. One of the primary challenges of molecular cancer epidemiology therefore is to improve exposure assessment. Progress has been made with biomarkers such as carcinogens and their metabolites, DNA and protein adducts and mutations measured in various tissues and body fluids. Nevertheless, much remains to be accomplished in order to establish aetiology and provide the evidence base for public health decisions. This review considers some of the principles behind the application of exposure biomarkers in cancer epidemiology. It also demonstrates how the same biomarkers can contribute both to establishing the biological plausibility of associations between exposure and disease and be valuable endpoints in intervention studies. The potential of new technologies such as transcriptomics, proteomics and metabonomics to provide a step change in environmental exposure assessment is discussed. An increasing recognition of the role of epigenetic changes in carcinogenesis presents a fresh challenge as alterations in DNA methylation, histone modification and microRNA in response to environmental exposures demand a new generation of exposure biomarker. The overall importance of this area of research is brought into sharp relief by the large prospective cohort studies (e.g. UK Biobank) which need accurate exposure measurement in order to shed light on the complex gene:environment interactions underlying common chronic disorders including cancer. It is suggested that a concerted effort is now required, with appropriate funding, to develop and

  17. Diagnosis and epidemiology of red blood cell enzyme disorders

    Richard Van Wijk

    2013-03-01

    Full Text Available The red blood cell possess an active metabolic machinery that provides the cell with energy to pump ions against electrochemical gradients, to maintain its shape, to keep hemoglobin iron in the reduced (ferrous form, and to maintain enzyme and hemoglobin sulfhydryl groups. The main source of metabolic energy comes from glucose. Glucose is metabolized through the glycolytic pathway and through the hexose monophosphate shunt. Glycolysis catabolizes glucose to pyruvate and lactate, which represent the end products of glucose metabolism in the erythrocyte. Adenosine diphosphate (ADP is phosphorylated to adenosine triphosphate (ATP, and nicotinamide adenine dinucleotide (NAD+ is reduced to NADH in glycolysis. 2,3- Bisphosphoglycerate, an important regulator of the oxygen affinity of hemoglobin, is generated during glycolysis by the Rapoport-Luebering shunt. The hexose monophosphate shunt oxidizes glucose-6-phosphate, reducing NADP+ to reduced nicotinamide adenine dinucleotide phosphate (NADPH. The red cell lacks the capacity for de novo purine synthesis but has a salvage pathway that permits synthesis of purine nucleotides from purine bases...

  18. Deaf Children with Autism Spectrum Disorders

    Szymanski, Christen A.; Brice, Patrick J.; Lam, Kay H.; Hotto, Sue A.

    2012-01-01

    Epidemiological studies investigating the prevalence of autism have increased in recent years, within the United States and abroad. However, statistics as to how many of those children may also have a comorbid hearing loss is lacking. The prevalence of school-administrator reported diagnosis of autism spectrum disorders (clinical diagnosis…

  19. Psychiatric Morbidity and Work and Social Adjustment Among Earthquake Survivors Extricated from under the Rubble

    Shamaila Aziz

    2012-01-01

    Full Text Available Objectives: This cross-sectional study examined psychiatric co-morbidity and work and social adjustment after a natural disaster among survivors who were extricated from under the rubble. Materials and Methods: Individuals (N=40 belonging to district Muzaffarabad, a severely earthquake affected area on 8 th October 2005, were interviewed. The examination included the MINI International Neuropsychiatric Interview for DSM-IV Axis I disorders, Work and Social Adjustment Scale, and questions covering background characteristics and disaster exposure. Results: The most prevalent disorders were posttaumatic stress disorder (32.5%, major depressive disorder (17.5%, dysthymia (15.0%, agoraphobia (25.0%, and panic disorder (20.0%. Moreover, 77% of the respondents have been diagnosed with at least one psychiatric disorder. Work and soical adjustment was found to have an inverse relationship with the psychiatric co-morbidity. Conclusion: Small sample size and lack of comparison group from non-earthquake struck areas may limit the generalizability of the psychatric disorders. Psychiatric disorders other than PTSD, especially depressive and anxiety disorders, are of clinical importance when considering long-term mental health effect of disasters.

  20. Tax Adjusted for Imported Equipment

    2010-01-01

    @@ Ministry of Finance, Central Administration of Customs, and State Administration of Taxation of P.R. of China jointly issued a "Notice on the Lists Related to the Interim Provisions on the Adjustment of Import Tax Policy on Major Technical Equipment" (the Notice) on April 13rd to adjust the list of equipment catalog and merchandise attached to the "Interim Provisions on the Import Tax Policy on Major Technical Equipment", as well as the preferential scope and extent of the import tax on a number of major technical equipment.

  1. Parent Report of Community Psychiatric Comorbid Diagnoses in Autism Spectrum Disorders

    Rosenberg, Rebecca E.; Kaufmann, Walter E; J. Kiely Law; Paul A. Law

    2011-01-01

    We used a national online registry to examine variation in cumulative prevalence of community diagnosis of psychiatric comorbidity in 4343 children with autism spectrum disorders (ASD). Adjusted multivariate logistic regression models compared influence of individual, family, and geographic factors on cumulative prevalence of parent-reported anxiety disorder, depression, bipolar disorder, and attention deficit/hyperactivity disorder or attention deficit disorder. Adjusted odds of community-as...

  2. About the Epidemiology and Genomics Research Program

    Epidemiology is the scientific study of the causes and distribution of disease in populations. NCI-funded epidemiology research is conducted through research at institutions in the United States and internationally.

  3. Why does epidemiology need better questionnaires?

    Tong, S.; Ring, I.; Olsen, Jørn

    2003-01-01

    The authors argue for the use of validated questionnaires whenever possible to improve the quality of epidemiological research.......The authors argue for the use of validated questionnaires whenever possible to improve the quality of epidemiological research....

  4. Mitochondrial DNA and Cancer Epidemiology Workshop

    A workshop to review the state-of-the science in the mitochondrial DNA field and its use in cancer epidemiology, and to develop a concept for a research initiative on mitochondrial DNA and cancer epidemiology.

  5. The epidemiology of genital human papillomavirus infection.

    Trottier, Helen; Franco, Eduardo L.

    2006-01-01

    KEYWORDS - CLASSIFICATION: cancer epidemiology;complications;Canada;epidemiology;Evaluation;Female;Genital Diseases,Female;Humans;Incidence;lifestyle modulation of cancer & cancer biomarkers;Papillomaviridae;Papillomavirus Infections;Risk Factors;Uterine Cervical Neoplasms;virology.

  6. 75 FR 33379 - Railroad Cost Recovery Procedures-Productivity Adjustment; Quarterly Rail Cost Adjustment Factor

    2010-06-11

    ... Surface Transportation Board Railroad Cost Recovery Procedures--Productivity Adjustment; Quarterly Rail... Railroads that the Board restate the previously published productivity adjustment for the 2003-2007 averaging period (2007 productivity adjustment) so that it tracks the 2007 productivity adjustment...

  7. Problem gambling and homelessness: results from an epidemiologic study.

    Nower, Lia; Eyrich-Garg, Karin M; Pollio, David E; North, Carol S

    2015-06-01

    The purpose of this study was to investigate the prevalence of gambling disorder and comorbid psychiatric disorders in a homeless population and identify features related to potential subtypes. At baseline, participants were administered a structured interview including socio-demographic sections of the National Comorbidity Study (NCS) interview; seven diagnostic sections of the Diagnostic Interview Schedule (DIS); the alcohol and drug abuse sections of the Composite International Diagnostic Interview-Substance Abuse Module (CIDI-SAM); and the Homeless Supplement to the DIS. At nine months post-baseline assessment, participants were administered additional NCS family history questions and the South Oaks Gambling Screen (SOGS). Participants were an epidemiologic sample of 275 predominately African-American homeless individuals, grouped as lifetime non-gamblers (n = 60), recreational gamblers (n = 152), and problem gamblers (n = 63), recruited on the street and through homeless shelters. Results indicate that lifetime rates of sub-clinical problem (46.2%) and disordered (12.0%) gambling were significantly higher than in the general population. Problem gamblers were more likely than non-problem gamblers to meet diagnostic criteria for antisocial personality disorder, post-traumatic stress disorder, bipolar disorder, and any psychiatric disorder, and more likely than non-gamblers to use illicit drugs or meet criteria for abuse/dependence for nicotine, alcohol, or any substance. This study provides evidence that problem gambling is a significant public health issue among the African-American homeless population. Homeless services should include assessment for problem gambling along with psychiatric disorders and referrals to resources and treatment programs. Future studies should explore the relationship of the onset and course of problem gambling and other psychiatric disorders with homelessness as well as racial differences in gambling patterns and problem severity

  8. Panic Disorder among Adults

    ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ...

  9. Antisocial Personality Disorder

    ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ...

  10. Bipolar Disorder Among Adults

    ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ...

  11. Any Personality Disorder

    ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ...

  12. Borderline Personality Disorder

    ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ...

  13. COPD exacerbations · 1: Epidemiology

    Donaldson, G C; Wedzicha, J A

    2006-01-01

    The epidemiology of exacerbations of chronic obstructive pulmonary disease (COPD) is reviewed with particular reference to the definition, frequency, time course, natural history and seasonality, and their relationship with decline in lung function, disease severity and mortality. The importance of distinguishing between recurrent and relapsed exacerbations is discussed.

  14. Nephrogenic systemic fibrosis: epidemiology update

    Marckmann, P.

    2008-01-01

    Purpose of review The aim of this article is to outline the history of nephrogenic systemic fibrosis, a new and serious disease of patients with renal failure, and to give an update on its aetiology and prevalence. Recent findings Epidemiological and histochemical studies demonstrated that...

  15. Brain Tumor Epidemiology Consortium (BTEC)

    The Brain Tumor Epidemiology Consortium is an open scientific forum organized to foster the development of multi-center, international and inter-disciplinary collaborations that will lead to a better understanding of the etiology, outcomes, and prevention of brain tumors.

  16. Epidemiological methods: a brief review

    Epidemiology, the study of disease distributions in populations and the factors which influence these distributions, is an observational science, i.e., its data base consists of measurements made on free living individuals characterized by presence or absence of disease states and putative risk factors. Epidemiological studies are usually classified as descriptive or analytical. Descriptive studies are primarily used for planning and evaluating health programs or to generate etiological hypotheses. Analytical studies are primarily used for testing etiological hypotheses. Analytical studies are designed either as cohort investigations in which populations with and without a putative risk factor are followed through time to ascertain their differential incidence of disease, or case-control investigations in which the history of exposure to a putative risk factor is compared among persons with a disease and appropriate controls free of disease. Both descriptive and analytical epidemiological studies have been applied to health physics problems. Examples of such problems and the epidemiological methods used to explore them will be presented

  17. Epidemiological studies and ionizing radiations

    After some generalities on epidemiological studies, this report presents the current status of knowledge and researches in three peculiar domains: leukaemia for young people living around nuclear power stations, pathologies in workers of the nuclear sector, and health condition (incidence of cancers) of populations living around nuclear power stations

  18. Methodologic Issues and Approaches to Spatial Epidemiology

    Beale, Linda; Abellan, Juan Jose; Hodgson, Susan; Jarup, Lars

    2008-01-01

    Spatial epidemiology is increasingly being used to assess health risks associated with environmental hazards. Risk patterns tend to have both a temporal and a spatial component; thus, spatial epidemiology must combine methods from epidemiology, statistics, and geographic information science. Recent statistical advances in spatial epidemiology include the use of smoothing in risk maps to create an interpretable risk surface, the extension of spatial models to incorporate the time dimension, an...

  19. The evolving epidemiology of inflammatory bowel disease.

    Shanahan, Fergus

    2009-07-01

    Epidemiologic studies in inflammatory bowel disease (IBD) include assessments of disease burden and evolving patterns of disease presentation. Although it is hoped that sound epidemiologic studies provide aetiological clues, traditional risk factor-based epidemiology has provided limited insights into either Crohn\\'s disease or ulcerative colitis etiopathogenesis. In this update, we will summarize how the changing epidemiology of IBD associated with modernization can be reconciled with current concepts of disease mechanisms and will discuss studies of clinically significant comorbidity in IBD.

  20. Relationship between acute and chronic disease epidemiology.

    Kuller, L.H. (Lewis H.)

    1987-01-01

    Epidemiology is the study of epidemics. The primary goal of epidemiological studies should be the identification of the determinants of disease in order to decrease morbidity and mortality. Epidemiological studies evolve through descriptive, analytical, and experimental approaches. The traditional infectious disease epidemiology studies were primarily concerned with identification of an agent, incubation period, mode of transmission, population at risk, and methods of disease control. Chronic...

  1. EPISCOPE: computer programs in veterinary epidemiology.

    Frankena, K; Noordhuizen, J P; Willeberg, P; van Voorthuysen, P F; Goelema, J O

    1990-06-01

    Veterinary epidemiology is a rapidly developing science. However, many veterinarians are unfamiliar with the relevant techniques because veterinary schools have not introduced biostatistics as a core element of their courses or adopted epidemiology as a specific discipline. EPISCOPE, the computer software presented in this paper, covers many epidemiological principles and calculations. It can assist both the teaching of epidemiology and the analysis of field data. PMID:2368305

  2. Adolescent Eating Disorder: Anorexia Nervosa.

    Muuss, Rolf E.

    1985-01-01

    Examines anorexia nervosa, an eating disorder seen with increasing frequency, especially among adolescent girls. Presents five theories about causation, discusses early characteristics, typical family patterns, physical and medical characteristics, social adjustment problems, and society's contribution to anorexia. Describes course of the…

  3. Clinical approaches to low back pain. Part 1. Epidemiology, diagnosis, and prevention.

    R. W. Teasell; White, K.

    1994-01-01

    The epidemiology and difficulties in diagnosing low back pain are discussed. Clinical investigations should be limited to those tests that will provide useful information for effective management. Prevention is the best strategy for avoiding low back pain but is realistically hard to practise because the disorder has many environmental and intrinsic risk factors.

  4. An Epidemiological Study of Number Processing and Mental Calculation in Greek Schoolchildren

    Koumoula, Anastasia; Tsironi, Vanda; Stamouli, Victoria; Bardani, Irini; Stavroula, Siapati; Graham, Annik; Kafantaris, Ignatios; Charalambidou, Irini; Dellatolas, Georges; von Aster, Michael

    2004-01-01

    The aim of this study was to validate and standardize an instrument for the diagnosis of developmental dyscalculia (mathematics disorder) in a Greek population and to obtain relevant epidemiological data. We used the "Neuropsychological Test Battery for Number Processing and Calculation in Children" (NUCALC) in a community sample of 240 students…

  5. A review of epidemiological injury studies in the oil- and gas offshore industry

    Jensen, Olaf; Laursen, Lise Hedegaard

    2014-01-01

    Safety and health in offshore oil and gas production has always been important. With the aim to evaluate the preventive program effect, a literature review was done based on epidemiological occupational injuries and musculoskeletal disorders. Methods: A literature review was performed by examining...... fatal occupational injury risk in the oil- and gas platforms calls for more attention....

  6. History and philosophy of modern epidemiology

    Andersen, Hanne

    2012-01-01

    Epidemiological studies of chronic diseases began around the mid-20th century. Contrary to the infectious disease epidemiology which had prevailed at the beginning of the 20th century and which had focused on single agents causing individual diseases, the chronic disease epidemiology which emerge...

  7. Cancer Epidemiology Matters Blog - 2015 Archive

    The Cancer Epidemiology Matters blog helps foster a dialogue between the National Cancer Institute's (NCI) Epidemiology and Genomics Research Program (EGRP), extramural researchers, and other individuals, such as clinicians, community partners, and advocates, who are interested in cancer epidemiology and genomics.

  8. Cancer Epidemiology Matters Blog - 2013 Archive

    The Cancer Epidemiology Matters blog helps foster a dialogue between the National Cancer Institute's (NCI) Epidemiology and Genomics Research Program (EGRP), extramural researchers, and other individuals, such as clinicians, community partners, and advocates, who are interested in cancer epidemiology and genomics.

  9. Cancer Epidemiology Matters Blog - 2014 Archive

    The Cancer Epidemiology Matters blog helps foster a dialogue between the National Cancer Institute's (NCI) Epidemiology and Genomics Research Program (EGRP), extramural researchers, and other individuals, such as clinicians, community partners, and advocates, who are interested in cancer epidemiology and genomics.

  10. Cancer Epidemiology Matters Blog - 2012 Archive

    The Cancer Epidemiology Matters blog helps foster a dialogue between the National Cancer Institute's (NCI) Epidemiology and Genomics Research Program (EGRP), extramural researchers, and other individuals, such as clinicians, community partners, and advocates, who are interested in cancer epidemiology and genomics.

  11. An adjustable contracted CI method

    王育彬; 甘正汀; 苏克和; 文振翼

    1999-01-01

    A new contracted CI scheme——adjustable contracted CI scheme——is presented and programed. The efficiency of this scheme is tested by some example calculations. The result shows that the application of the new scheme is flexible and the correlation energy loss is lower than that of the original externally contracted CI method.

  12. Self-Adjusting Stack Machines

    Hammer, Matthew A; Chen, Yan; Acar, Umut A

    2011-01-01

    Self-adjusting computation offers a language-based approach to writing programs that automatically respond to dynamically changing data. Recent work made significant progress in developing sound semantics and associated implementations of self-adjusting computation for high-level, functional languages. These techniques, however, do not address issues that arise for low-level languages, i.e., stack-based imperative languages that lack strong type systems and automatic memory management. In this paper, we describe techniques for self-adjusting computation which are suitable for low-level languages. Necessarily, we take a different approach than previous work: instead of starting with a high-level language with additional primitives to support self-adjusting computation, we start with a low-level intermediate language, whose semantics is given by a stack-based abstract machine. We prove that this semantics is sound: it always updates computations in a way that is consistent with full reevaluation. We give a comp...

  13. Adjustable Optical-Fiber Attenuator

    Buzzetti, Mike F.

    1994-01-01

    Adjustable fiber-optic attenuator utilizes bending loss to reduce strength of light transmitted along it. Attenuator functions without introducing measurable back-reflection or insertion loss. Relatively insensitive to vibration and changes in temperature. Potential applications include cable television, telephone networks, other signal-distribution networks, and laboratory instrumentation.

  14. Adjustment or updating of models

    D J Ewins

    2000-06-01

    In this paper, first a review of the terminology used in the model adjustment or updating is presented. This is followed by an outline of the major updating algorithms cuurently available, together with a discussion of the advantages and disadvantages of each, and the current state-of-the-art of this important application and part of optimum design technology.

  15. The relationship between the Five-Factor Model and latent DSM-IV personality disorder dimensions

    Nestadt, Gerald; Costa, Paul T.; Hsu, Fang-Chi; Samuels, Jack; Bienvenu, O. Joseph; Eaton, William W.

    2007-01-01

    This study compared the latent structure of the DSM-IV personality disorders to the Five-Factor Model (FFM) of general personality dimensions. The subjects in the study were 742 community-residing individuals who participated in the Hopkins Epidemiology of Personality Disorder Study. DSM-IV personality disorder traits were assessed by psychologists using the International Personality Disorder Examination, and personality disorder dimensions were derived previously using dichotomous factor ana...

  16. Anxiety and Anxiety Disorders in Children and Adolescents: Developmental Issues and Implications for DSM-V

    Beesdo, Katja; Knappe, Susanne; Pine, Daniel S.

    2009-01-01

    This review summarizes findings on the epidemiology and etiology of anxiety disorders among children and adolescents including separation anxiety disorder, specific phobia, social phobia, agoraphobia, panic disorder, and generalized anxiety disorder, also highlighting critical aspects of diagnosis, assessment, and treatment. Childhood and adolescence is the core risk phase for the development of anxiety symptoms and syndromes, ranging from transient mild symptoms to full-blown anxiety disorde...

  17. Comorbid mental disorders among the patients with alcohol abuse and dependence in Korea.

    Cho, Maeng Je; Hahm, Bong-Jin; Suh, Tongwoo; Suh, Guk-Hee; Cho, Seong-Jin; Lee, Chung Kyoon

    2002-01-01

    This study investigated the patterns of alcohol disorder comorbidity with other psychiatric disorders, using Korean nationwide epidemiological data. By two-stage cluster sampling, 5,176 adult household residents of Korea were interviewed using the Korean version of the Diagnostic Interview Schedule. Psychiatric disorders strongly associated with alcohol disorders were, other drug abuse or dependence, major depression, simple phobia, antisocial personality disorder, tobacco dependence, and pat...

  18. The burden of disease in Zimbabwe in 1997 as measured by disability-adjusted life years lost

    Chapman, Glyn; Hansen, Kristian Schultz; Jelsma, Jennifer;

    2006-01-01

    Objective To rank health problems contributing most to the burden of disease in Zimbabwe using Disability-Adjusted Life Years as the population health measure. Methods Epidemiological information was derived from multiple sources. Population size and total number of deaths by age and sex for the...

  19. Epidemiology and consequences of women's revictimization.

    Kimerling, Rachel; Alvarez, Jennifer; Pavao, Joanne; Kaminski, Amy; Baumrind, Nikki

    2007-01-01

    This study uses Kraemer's approach for nonrandom comorbidity to identify the parameters of revictimization among women, using a diverse, population-based sample. Participants (n = 11,056) are from the California Women's Health Survey. Women were asked about childhood and adult violence and current symptoms of posttraumatic stress disorder (PTSD), depression, and anxiety. Logistic regressions adjusted for age, ethnicity, education, and poverty indicate that women who experienced childhood physical or sexual abuse were 5.8 (95% confidence interval, 5.2-6.4) times more likely to experience adult physical or sexual victimization. Revictimization affected 12% of women, and these women were substantially more likely to report current symptoms of anxiety, depression, and PTSD than women exposed to violence only in childhood or only as an adult. Revictimization is a methodologically distinct concept and is a potent risk factor for adult mental health problems. Prevention should target women exposed to both physical and sexual assault. PMID:17403467

  20. Indian Psychiatric epidemiological studies: Learning from the past

    Math, Suresh Bada; Srinivasaraju, Ravindra

    2010-01-01

    The objective of this paper is to provide a systematic review on the epidemiology of psychiatric disorders in India based on the data published from 1960 to 2009. Extensive search of PubMed, NeuroMed, Indian Journal of Psychiatry website and MEDLARS using search terms “psychiatry” “prevalence”, “community”, and “epidemiology” was done along with the manual search of journals and cross-references. Retrieved articles were systematically selected using specific inclusion and exclusion criteria. ...

  1. Association of attention-deficit/hyperactivity disorder with gambling disorder.

    Retz, Wolfgang; Ringling, Jutta; Retz-Junginger, Petra; Vogelgesang, Monika; Rösler, Michael

    2016-08-01

    Attention-deficit/hyperactivity disorder (ADHD) is a frequent mental disorder with childhood onset and high persistence into adulthood. There is much evidence that ADHD increases the risk for the development of other psychiatric disorders and functional problems in several domains of everyday life. In this study, the association of ADHD with gambling disorder (GD) was investigated. 163 adult subjects suffering from GD were examined for childhood and current ADHD according to DSM-5 as well as co-morbid psychiatric disorders. Moreover, characteristics of gambling behavior have been evaluated. The prevalence of lifetime ADHD was 28.8 %, with 25.2 % of the study population presenting ADHD as a full syndrome according to DSM-5. The prevalence of co-morbid substance use disorders and adjustment disorders and cluster B personality disorders was higher in GD patients with current ADHD than in the group without. Also, an increased rate of suicide attempts was detected in gamblers with ADHD. In contrast with gamblers without ADHD, those with ADHD were reported to spend more time with gambling, a sedative effect of gambling and a faster development of GD. The high prevalence of ADHD in patients with GD indicates that childhood ADHD is a risk factor for the development of GD in later life. Moreover, treatment of patients with GD and ADHD is complicated by a high rate of co-morbid disorders. Regarding therapeutic approaches, it should be considered that functional aspects of gambling differ in GD patients with and without ADHD. PMID:27328979

  2. Behaviorial inhibition and history of childhood anxiety disorders in Brazilian adult patients with panic disorder and social anxiety disorder Comportamento inibido e história de transtornos de ansiedade na infância em pacientes brasileiros adultos com transtorno do pânico e transtorno de ansiedade social

    Luciano Rassier Isolan; Cristian Patrick Zeni; Kelin Mezzomo; Carolina Blaya; Leticia Kipper; Elizeth Heldt; Gisele Gus Manfro

    2005-01-01

    PURPOSE: To evaluate the presence of behavioral inhibition and anxiety disorders during childhood in Brazilian adult patients with panic disorder and social anxiety disorder compared to a control group. METHODS: Fifty patients with panic disorder, 50 patients with social anxiety disorder, and 50 control subjects were included in the study. To assess the history of childhood anxiety, the Schedule for Affective Disorders and Schizophrenia for School Age Children, Epidemiologic Version (K-SADS-E...

  3. Bases epidemiológicas para análise das más oclusões morfológicas como fatores de risco no desenvolvimento das desordens temporomandibulares de origem articular Epidemiological basis for the analysis of morphologic malocclusion as a risk factor for the development of temporomandibular joint disorders

    Ricardo de Souza Tesch

    2004-10-01

    desnecessário.Among the researches undertaken in epidemiology, a peculiar group of pathologies present either unknown or not totally understood origins. Temporomandibular disorders (TMD can be classified in this subgroup. Three basic observational strategies have been used to approach the etiologic role of malocclusion in TMD development, inside the epidemiological repertoire. They are sectional, case-control and cohort studies. Some clinical trials are conducted based on the removal of the suspect etiologic factor. Based on the literature reviewed in terms of the methodology applied in the selected studies, we can infer that: the definition of possible etiological factors related to specific sub-groups of TMD is primordial not to underestimate the role of malocclusion in the development of this kind of disorders; the characterization of a normal occlusion like the one associated with the lower risk for TMD problems development can be useful, but the application of these parameters will probably result inappropriate for the resolution of a joint problem which is already established; the concept of lower risk occlusion would involve a small slide discrepancy between RCP and ICP, small incisal overlap, positive overbite and no posterior crossbite. This concept is similar to the concept of normal occlusion supported for decades, although a deviation from the normal criterion instead of an absolute criterion must be tolerated; although it may be prudent to establish therapeutic morphologic goals that seek what is observed in untreated occlusions deemed normal or ideal, the establishment of an occlusion that reach all these gnathologic criteria, by means of orthodontic treatment, might be either impossible or probably unnecessary.

  4. Seven mistakes and potential solutions in epidemiology, including a call for a World Council of Epidemiology and Causality

    Bhopal Raj

    2009-12-01

    Full Text Available Abstract All sciences make mistakes, and epidemiology is no exception. I have chosen 7 illustrative mistakes and derived 7 solutions to avoid them. The mistakes (Roman numerals denoting solutions are: 1. Failing to provide the context and definitions of study populations. (I Describe the study population in detail 2. Insufficient attention to evaluation of error. (II Don't pretend error does not exist. 3. Not demonstrating comparisons are like-for-like. (III Start with detailed comparisons of groups. 4. Either overstatement or understatement of the case for causality. (IV Never say this design cannot contribute to causality or imply causality is ensured by your design. 5. Not providing both absolute and relative summary measures. (V Give numbers, rates and comparative measures, and adjust summary measures such as odds ratios appropriately. 6. In intervention studies not demonstrating general health benefits. (VI Ensure general benefits (mortality/morbidity before recommending application of cause-specific findings. 7. Failure to utilise study data to benefit populations. (VII Establish a World Council on Epidemiology to help infer causality from associations and apply the work internationally. Analysis of these and other common mistakes is needed to benefit from the increasing discovery of associations that will be multiplying as data mining, linkage, and large-scale scale epidemiology become commonplace.

  5. 12 CFR 19.240 - Inflation adjustments.

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Inflation adjustments. 19.240 Section 19.240... PROCEDURE Civil Money Penalty Inflation Adjustments § 19.240 Inflation adjustments. (a) The maximum amount... Civil Penalties Inflation Adjustment Act of 1990 (28 U.S.C. 2461 note) as follows: ER10NO08.001 (b)...

  6. Gender Differences in Animal Models of Posttraumatic Stress Disorder

    Hagit Cohen; Rachel Yehuda

    2011-01-01

    Epidemiological studies report higher prevalence rates of stress-related disorders such as acute stress disorder and post-traumatic stress disorder (PTSD) in women than in men following exposure to trauma. It is still not clear whether this greater prevalence in woman reflects a greater vulnerability to stress-related psychopathology. A number of individual and trauma-related characteristics have been hypothesized to contribute to these gender differences in physiological and psychological re...

  7. Insomnia as a Transdiagnostic Process in Psychiatric Disorders

    Dolsen, Michael R.; Asarnow, Lauren D.; Harvey, Allison G.

    2014-01-01

    Insomnia is a major public health concern, and is highly comorbid with a broad range of psychiatric disorders. Although insomnia has historically been considered a symptom of other disorders, this perspective has shifted. Epidemiological and experimental studies suggest that insomnia is related to the onset and course of several psychiatric disorders. Furthermore, several randomized controlled trials show that cognitive behavioral therapy for insomnia delivered to individuals who meet diagnos...

  8. Bullous disorders in Konya: A study of 93 cases

    Munise Daye; İnci Mevlitoğlu; Sarenur Esener

    2013-01-01

    Background and Design: Bullous disorders are a group of disorders caused by specific antibodies against tissue adhesion molecules in skin and mucosa or genetic inheritance. There are limited detailed epidemiological studies about bullous disorders in Turkey. In this study we evaluated the demographic, clinical, immunopathologic, course and follow-up properties, cases in Konya. Most of cases were in pemphigus and bullous pemphigoid group, so we gave more information about them. Materials a...

  9. An overview of Indian research in anxiety disorders

    Trivedi, J.K.; Gupta, Pawan Kumar

    2010-01-01

    Anxiety is arguably an emotion that predates the evolution of man. Its ubiquity in humans, and its presence in a range of anxiety disorders, makes it an important clinical focus. Developments in nosology, epidemiology and psychobiology have led to significant advancement in our understanding of the anxiety disorders in recent years. Advances in pharmacotherapy and psychotherapy of these disorders have brought realistic hope for relief of symptoms and improvement in functioning to patients. Ne...

  10. Personality Disorders

    Personality disorders are a group of mental illnesses. They involve long-term patterns of thoughts and behaviors ... serious problems with relationships and work. People with personality disorders have trouble dealing with everyday stresses and ...

  11. Mathematics disorder

    ... this page: //medlineplus.gov/ency/article/001534.htm Mathematics disorder To use the sharing features on this page, please enable JavaScript. Mathematics disorder is a condition in which a child's ...

  12. Rumination disorder

    ... this page: //medlineplus.gov/ency/article/001539.htm Rumination disorder To use the sharing features on this page, please enable JavaScript. Rumination disorder is a condition in which a person ...

  13. Panic disorder

    American Psychiatric Association. Diagnostic and statistical manual of mental disorders . 5th ed. Arlington, VA: American Psychiatric Publishing. 2013. Hofmann SG, Smits JA. Cognitive-behavioral therapy for adult anxiety disorders: ...

  14. Metabolic Disorders

    ... as your liver, muscles, and body fat. A metabolic disorder occurs when abnormal chemical reactions in your body ... that produce the energy. You can develop a metabolic disorder when some organs, such as your liver or ...

  15. Eating Disorders

    Eating disorders are serious behavior problems. They can include severe overeating or not consuming enough food to stay ... concern about your shape or weight. Types of eating disorders include Anorexia nervosa, in which you become too ...

  16. Cyclothymic disorder

    American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders . 5th ed. Arlington, VA: American Psychiatric Publishing, 2013. Peris RH. Bipolar disorder. In: Stern TA, Rosenbaum JF, Fava M, ...

  17. Anxiety Disorders

    ... press the Escape (Esc) button on your keyboard.) Anxiety Disorders in Older Adults Click for more information Studies estimate that anxiety ... anxiety symptoms or make them worse. In older adults, anxiety disorders often occur at the same time as depression, ...

  18. Bipolar Disorder

    Bipolar disorder is a serious mental illness. People who have it go through unusual mood changes. They go ... The down feeling is depression. The causes of bipolar disorder aren't always clear. It runs in families. ...

  19. Personality Disorders

    ... for Building a Healthy Self-Image and Improving Self-Esteem 8 Things You Should Know About Body Dysmorphic ... personality disorder. Personality disorders are usually recognizable by adolescence or earlier, continue throughout adulthood, and become less ...

  20. Mood Disorders

    ... include depression and bipolar disorder (also called manic depression). Mood disorders can increase a person's risk for heart disease, diabetes, and other diseases. Treatments include medication, psychotherapy, or a combination of both. With treatment, most ...

  1. Bleeding Disorders

    ... as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or ... don't work the way they should. Bleeding disorders can be the result of other diseases, such ...

  2. Voice Disorders

    ... on the vocal cords. Other causes of voice disorders include infections, upward movement of stomach acids into ... become an effort to talk Treatment for voice disorders varies depending on the cause. Most voice problems ...

  3. Platelet Disorders

    ... higher risk of blood clots. With other platelet disorders, the platelets do not work as they should. ... This can cause excessive bleeding. Treatment of platelet disorders depends on the cause. NIH: National Heart, Lung, ...

  4. Bipolar Disorder

    Bipolar disorder is a serious mental illness. People who have it go through unusual mood changes. They ... The down feeling is depression. The causes of bipolar disorder aren't always clear. It runs in ...

  5. Genetic epidemiology of Scheuermann's disease

    Damborg, Frank; Engell, Vilhelm; Nielsen, Jan;

    2011-01-01

    The genetic/environmental etiology of Scheuermann's disease is unclear. We estimated the heritability of the disease using an etiological model adjusted for sex and time of diagnosis, and examined whether the prevalence of Scheuermann's disease was constant over time....

  6. Does adjustment for measurement error induce positive bias if there is no true association?

    Burstyn, Igor

    2009-01-01

    This article is a response to an off-the-record discussion that I had at an international meeting of epidemiologists. It centered on a concern, perhaps widely spread, that measurement error adjustment methods can induce positive bias in results of epidemiological studies when there is no true association. I trace the possible history of this supposition and test it in a simulation study of both continuous and binary health outcomes under a classical multiplicative measurement error model. A B...

  7. Posttraumatic stress disorder and trauma characteristics are correlates of premenstrual dysphoric disorder

    Pilver, Corey E.; Levy, Becca R.; Libby, Daniel J.; Desai, Rani A.

    2011-01-01

    Posttraumatic stress disorder (PTSD) is often comorbid with premenstrual dysphoric disorder (PMDD) in women; however, it is unclear whether this relationship is driven by the trauma that may lead to PTSD or if PTSD is uniquely associated with PMDD. In this study, we examine trauma and PTSD as independent correlates of PMDD. Researchers conducted a cross-sectional, secondary data analysis of 3,968 female participants (aged 18–40) of the Collaborative Psychiatric Epidemiology Surveys. Women who...

  8. Panic disorder.

    Snaith, R P

    1983-01-01

    Panic disorder is characterised by recurrent, unpredictable panic attacks, making people worry about or change their behaviour to avert subsequent panic attacks or their consequences. Panic disorder occurs in up to 3% of the adult population at some time, and is associated with other psychiatric and personality disorders, and with drug and alcohol abuse.The risk of suicide and attempted suicide has been found to be higher in people with panic disorder than in people with other psychiatric ...

  9. Eating Disorders

    Ahmad Farah; Celasun Nalan; Gucciardi Enza; Stewart Donna E

    2004-01-01

    Abstract Health Issue Eating disorders are an increasing public health problem among young women. Anorexia and bulimia may give rise to serious physical conditions such as hypothermia, hypotension, electrolyte imbalance, endocrine disorders, and kidney failure. Key Issues Eating disorders are primarily a problem among women. In Ontario in 1995, over 90% of reported hospitalized cases of anorexia and bulimia were women. In addition to eating disorders, preoccupation with weight, body image and...

  10. Effects of Timing of Adversity on Adolescent and Young Adult Adjustment.

    Kiff, Cara J; Cortes, Rebecca; Lengua, Lilana; Kosterman, Rick; Hawkins, J David; Mason, W Alex

    2012-06-01

    Effects of Timing of Adversity on Adolescent and Young Adult Adjustment Abstract Exposure to adversity during childhood and adolescence predicts adjustment across development. Further, adolescent adjustment problems persist into young adulthood. This study examined relations of contextual adversity with concurrent adolescent adjustment and prospective mental health and health outcomes in young adulthood. A longitudinal sample (N = 808) was followed from age 10 through 27. Perceptions of neighborhood in childhood predicted depression, alcohol use disorders, and HIV risk in young adulthood. Further, the timing of adversity was important in determining the type of problem experienced in adulthood. Youth adjustment predicted adult outcomes, and in some cases, mediated the relation between adversity and outcomes. These findings support the importance of adversity in predicting adjustment and elucidate factors that affect outcomes into young adulthood. PMID:22754271

  11. Differences in depressive symptoms between Korean and American outpatients with major depressive disorder.

    Jeon, Hong Jin; Walker, Rosemary S; Inamori, Aya; Hong, Jin Pyo; Cho, Maeng Je; Baer, Lee; Clain, Alisabet; Fava, Maurizio; Mischoulon, David

    2014-05-01

    Previous epidemiologic studies have revealed that East-Asian populations experience fewer depressive symptoms than American populations do. However, it is unclear whether this difference applies to clinical patients with major depressive disorder (MDD). This present study included 1592 Korean and 3744 American outpatients who were 18 years of age or older and met the Diagnostic and Statistical Manual of Mental Disorders, 4th ed. criteria for single or recurrent episodes of nonpsychotic MDD, and evaluated their symptoms of depression using the Hamilton Depression Rating Scale and the Quality of Life Enjoyment and Satisfaction Questionnaire Short Form. Korean patients scored significantly lower for guilt and depressed mood items, and higher for hypochondriasis and suicidality items than American patients did, after adjusting for total Hamilton Depression Rating Scale scores. Conversely, no significant differences were found in quality and function of daily life between groups. Multivariate logistic regression analyses revealed that Korean patients experienced less frequent depressed mood and guilt, including verbal and nonverbal expression of depressed mood [adjusted odds ratio (AOR) = 0.14, 95% confidence interval (CI) 0.08-0.23] and feelings of punishment (AOR = 0.036, 95% CI 0.025-0.054) when compared with Americans after adjusting for age and sex. Conversely, Korean patients experienced more frequent suicidality and hypochondriasis, including suicidal ideas or gestures (AOR = 2.10, 95% CI 1.60-2.76) and self-absorption of hypochondriasis (AOR = 1.94, 95% CI 1.70-2.20). In conclusion, decreased expression of depressed mood and guilt may cause underdiagnosis of MDD in Korean patients. Early diagnosis of and intervention for depression and suicide may be delayed because of this specific cross-cultural difference in depression symptoms. PMID:24323201

  12. DSM-5, psychiatric epidemiology and the false positives problem.

    Wakefield, J C

    2015-06-01

    The revision effort leading to the publication of the fifth edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM-5) was flawed in process, goals and outcome. The revision process suffered from lack of an adequate public record of the rationale for changes, thus shortchanging future scholarship. The goals, such as dimensionalising diagnosis, incorporating biomarkers and separating impairment from diagnosis, were ill-considered and mostly abandoned. However, DSM-5's greatest problem, and the target of the most vigorous and sustained criticism, was its failure to take seriously the false positives problem. By expanding diagnosis beyond plausible boundaries in ways inconsistent with DSM-5's own definition of disorder, DSM-5 threatened the validity of psychiatric research, including especially psychiatric epidemiology. I present four examples: increasing the symptom options while decreasing the diagnostic threshold for substance use disorder, elimination of the bereavement exclusion from major depression, allowing verbal arguments as evidence of intermittent explosive disorder and expanding attention-deficit/hyperactivity disorder to adults before addressing its manifest false positives problems. PMID:25675983

  13. Neuronal cell adhesion genes: key players in risk for schizophrenia, bipolar disorder and other neurodevelopmental brain disorders?

    Corvin, Aiden

    2010-01-01

    The major mental disorders, schizophrenia and bipolar disorder, are substantially heritable. Recent genomic studies have identified a small number of common and rare risk genes contributing to both disorders and support epidemiological evidence that genetic susceptibility overlaps between them. Prompted by the question of whether risk genes cluster in specific molecular pathways or implicate discrete mechanisms, we and others have developed hypothesis-free methods of investigating genome-wide...

  14. The Developmental Mental-Disorder Histories of Adults With Posttraumatic Stress Disorder: A Prospective Longitudinal Birth Cohort Study

    Koenen, Karestan C.; Moffitt, Terrie E; Caspi, Avshalom; Gregory, Alice; Harrington, HonaLee; Poulton, Richie

    2008-01-01

    Clinical and epidemiologic studies have established that posttraumatic stress disorder (PTSD) is highly comorbid with other mental disorders. However, such studies have largely relied on adults' retrospective reports to ascertain comorbidity. The authors examined the developmental mental health histories of adults with PTSD using data on mental disorders assessed across the first 3 decades of life among members of the longitudinal Dunedin Multidisciplinary Health and Development Study; 100% o...

  15. Multi-toning Image Adjustment

    LIU Shi-guang; WANG Xiao-juan; PENG Qun-sheng

    2011-01-01

    Due to the different lighting environments or other reasons, the pixel colors may be quite different in one image which causes distinct visual discontinuities. It makes the analysis and processing of such an image more difficult and sometime impossible. In this paper, a unified multi-toning image adjustment method is proposed to solve this problem. First, a novel unsupervised clustering method was proposed to partition the source and the target image into a certain number of subsets with similar color statistics. By matching the texture characteristics and luminance distribution between the blocks, it can create optimized correspondence. Then, the color information was transferred from the matched pixels in the source blocks to the target ones. Graph cut method was used to optimize the seams between different subsets in the final step. This method can automatically perform color adjustment of a multi-toning image. It is simple and efficient. Various results show the validity of this method.

  16. Auditory Processing Disorders

    Auditory Processing Disorders Auditory processing disorders (APDs) are referred to by many names: central auditory processing disorders , auditory perceptual disorders , and central auditory disorders . APDs ...

  17. Bipolar Disorder.

    Spearing, Melissa

    Bipolar disorder, a brain disorder that causes unusual shifts in a person's mood, affects approximately one percent of the population. It commonly occurs in late adolescence and is often unrecognized. The diagnosis of bipolar disorder is made on the basis of symptoms, course of illness, and when possible, family history. Thoughts of suicide are…

  18. Control of Adjustable Compliant Actuators

    Berno J.E. Misgeld; Kurt Gerlach-Hahn; Daniel Rüschen; Anake Pomprapa; Steffen Leonhardt

    2014-01-01

    Adjustable compliance or variable stiffness actuators comprise an additional element to elastically decouple the actuator from the load and are increasingly applied to human-centered robotic systems. The advantages of such actuators are of paramount importance in rehabilitation robotics, where requirements demand safe interaction between the therapy system and the patient. Compliant actuator systems enable the minimization of large contact forces arising, for example, from muscular spasticity...

  19. Parenting Perfectionism and Parental Adjustment

    Lee, Meghan A.; Schoppe-Sullivan, Sarah J.; Kamp Dush, Claire M.

    2012-01-01

    The parental role is expected to be one of the most gratifying and rewarding roles in life. As expectations of parenting become ever higher, the implications of parenting perfectionism for parental adjustment warrant investigation. Using longitudinal data from 182 couples, this study examined the associations between societal- and self-oriented parenting perfectionism and new mothers’ and fathers’ parenting self-efficacy, stress, and satisfaction. For mothers, societal-oriented parenting perf...

  20. Focal Adjustment for Star Tracker

    Liu Hai-bo; Jian-kun Yang; Ji-chun Tan; De-zhi Su; Wen-liang Wang; Xiu-jian Li; Hui Jia

    2010-01-01

    Technique of measuring intensity distribution and size of spot image developed has been discussed, which is especially suitable for defocus adjustment in ground test of star tracker. A novel approach for choosing a proper defocusing position has been proposed based on collimator, Gaussian surface fitting method, and other ordinary instruments. It proves to be practical and adequate in the development of distant object tracking such as star tracker.Defence Science Journal, 2010, 60(6), pp.678-...