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Sample records for activity programme kiss

  1. Perceptions of Sexual Violations: Denying a Kiss, Stealing a Kiss.

    Semonsky, Michael R.; Rosenfeld, Lawrence B.

    1994-01-01

    Compares the perceptions of 387 male and female undergraduates of a scene involving a minor sexual violation in which 1 participant denies a kiss and the other kisses regardless. Differences in perceptions of offender and denier behavior are discussed with reference to social support for determining sexual behavior. (SLD)

  2. Haploinsufficiency in the prometastasis Kiss1 Receptor Gpr54 delays breast tumor initiation, progression and lung metastasis

    Cho, Sung-Gook; Wang, Ying; Rodriguez, Melissa; Tan, Kunrong; Zhang, Wenzheng; Luo, Jian; Li, Dali; Liu, Mingyao

    2016-01-01

    Activation of KISS1 receptor (KISS1R or GPR54) by its ligands (kisspeptins) regulates a diverse function both in normal physiology and pathophysiology. In cancer, KISS1-induced KISS1R signaling is known to inhibit tumor angiogenesis and metastasis. However, roles of KISS1 and KISS1R in earlier stages of tumor progression and metastasis in vivo are still unknown. In this study, we demonstrate a critical role for Kiss1r in early stages of tumor progression using mouse tumor models. PyMT/Kiss1r mice with different Kiss1r genotypes were obtained by crossing MMTV-PyMT transgenic mouse with Kiss1r heterozygous mouse (Kiss1r+/−). Kiss1r heterozygosity attenuated breast tumor initiation, growth, latency, multiplicity and metastasis in MMTV-PyMT/Kiss1r+/− mouse models. To confirm the effects of Kiss1r in tumor progression and limit any effect of endogenous hormones, we isolated primary tumor cells from PyMT/Kiss1r+/+ or PyMT/Kiss1r+/− mice and performed in vitro and in vivo tumorigenesis assays. Kiss1r heterozygosity inhibited PyMT-induced in vitro tumorigeneity and in vivo tumor growth in NOD.SCID/NCr mice. To understand the underlying mechanism, we showed that activation of KISS1R by kisspeptin-10 led to RhoA activation and RhoA-dependent gene expression through Gαq-p63RhoGEF signaling pathway. Furthermore, anchorage-independent growth was tightly linked to the dosage-dependent regulation of RhoA by KISS1R. When MCF10A cells overexpressing H-RasV12 were subjected to in vitro tumorigenesis assays, knockdown of KISS1R or inactivation of RhoA in MCF10A cells reduced Ras-induced anchorage-independent growth, similar to our data obtained from PyMT-Kiss1r+/− mouse models. Altogether, we conclude that Kiss1r haploinsufficiency delays breast tumor initiation, progression and metastasis through its downstream Gαq-p63RhoGEF-RhoA signaling pathway. PMID:21852382

  3. Kiss1 mutant placentas show normal structure and function

    Herreboudt, A.M.; Kyle, V.R.L.; Lawrence, J.; Doran, J.; Colledge, W H

    2014-01-01

    Introduction Kisspeptins, encoded by the Kiss1 gene, are a set of related neuropeptides that are required for activation of the mammalian reproductive axis at puberty and to maintain fertility. In addition, kisspeptin signaling via the G-protein coupled receptor GPR54 (KISS1R) has been suggested to regulate human placental formation and correlations have been found between altered kisspeptin levels in the maternal blood and the development of pre-eclampsia. Methods We have used Kis...

  4. ``Sweetening'' Technical Physics with Hershey's Kisses

    Stone, Chuck

    2003-04-01

    This paper describes an activity in which students measure the mass of each candy in one full bag of Hershey's Kisses and then use a simple spreadsheet program to construct a histogram showing the number of candies as a function of mass. Student measurements indicate that one single bag of 80 Kisses yields enough data to produce a noticeable variation in the candy's mass distribution. The bimodal character of this distribution provides a useful discussion topic. This activity can be performed as a classroom project, a laboratory exercise, or an interactive lecture demonstration. In all these formats, students have the opportunity to collect, organize, process, and analyze real data. In addition to strengthening graphical analysis skills, this activity introduces students to fundamentals of statistics, manufacturing processes in the industrial workplace, and process control techniques.

  5. Developmental Profile and Sexually Dimorphic Expression of Kiss1 and Kiss1r in the Fetal Mouse Brain

    StuartTobet

    2013-10-01

    Full Text Available The hypothalamic-pituitary-gonadal axis (HPG is a complex neuroendocrine circuit involving multiple levels of regulation. Kisspeptin neurons play essential roles in controlling the HPG axis from the perspectives of puberty onset, oscillations of gonadotropin releasing hormone (GnRH neuron activity and the pre-ovulatory LH surge. The current studies focus on the expression of kisspeptin during murine fetal development using in situ hybridization (ISH, quantitative reverse transcription real-time PCR (QPCR and immunocytochemistry. Expression of mRNA coding for kisspeptin (KISS1 and its receptor KISS1R was observed at embryonic (E day 13 by ISH. At E13 and other later ages examined, Kiss1 signal in individual cells within the arcuate nucleus (ARC appeared stronger in females than males. ISH examination of agonadal steroidogenic factor-1 (Sf1 knockout mice revealed that E17 XY knockouts resembled wild-type XX females. These findings raise the possibility that gonadal hormones modulate the expression of Kiss1 in the ARC prior to birth. The sex and genotype differences were tested quantitatively by QPCR experiments in dissected hypothalami from mice at E17 and adulthood. Females had significantly more Kiss1 than males at both ages, even though the number of cells detected by ISH was similar. In addition, QPCR revealed a significant difference in the amount of Kiss1 mRNA in Sf1 mice with wild-type (WT XY mice expressing less than XY knockouts (KO and XX mice of both genotypes. The detection of immunoreactive KISS1 in perikarya of the ARC at E17 indicates that early mRNA is translated to peptide. The functional significance of this early expression of Kiss1 awaits elucidation.

  6. Inspection of licensee - Maintenance programme and activities

    An effective maintenance programme is critical to sustained safe and reliable operation of nuclear power plants. The Working Group on Inspection Practices (WGIP) concluded that when a licensee has an effective maintenance programme, the overall operating safety of the plant is improved and the protection of public health and safety enhanced. All Regulatory Bodies (RB) consider maintenance to be an important area for oversight. Although a variety of inspection practices are being used; RB are actively monitoring licensee performance. Specifically the following conclusions were reached and commendable practices identified: - Maintenance oversight by regulators appears to be in a stable continuous improvement state. Most regulators are executing inspection oversight based on an existing regulatory framework. - The performance of a licensee's maintenance programme is recognized as important part of maintaining nuclear safety. The result of the maintenance program assessment is included in the overall performance assessment of a license. - Maintenance inspection activities are recognized as an important part of the regulatory oversight process. Inspection activities are based on the safety significance and nature of work being performed by the licensee. - The effectiveness of the maintenance inspection activities is recognized to rely on properly qualified inspectors; who are adequately supported by specialists. Training and qualification of inspectors should be based on how the RB reviews and inspects licensee maintenance programmes. - Reporting requirements are identified to provide information on the licensees maintenance programme, and to help guide inspection activities. - Performance Indicators are recognized as a useful tool for helping focus regulatory activities. Basic PI are identified and tracked by the RB, and use of PI by the licensee is monitored. - Inspections are designed to confirm that the licensee is planning and scheduling maintenance with due

  7. Microarray of programmable electrochemically active elements

    S. McCaskill, John; Maeke, Thomas; Straczek, Lukas; Oehm, Jürgen; Funke, Dominic; Mayr, Pierre; Sharma, Abhishek; Müller, Asbjørn; Tangen, Uwe; H. Packard, Norman; Rasmussen, Steen

    This paper describes possible applications of a two dimensional array of programmable electrochemically active elements to Alife. The array has been developed as part of the MICREA-gents project, and after several design phases, is now a mature enough device for general use beyond the project. He...

  8. Three Kisses%三个吻

    2006-01-01

    @@ During our marriage,my wife and I have always exchanged not just one kiss,but three kisses when we departed company. It has brought snickers and chuckles from others,usually our daughters. What is the significance of the three kisses?

  9. Present activities of the Danube environmental Programme

    The international character of the Danube river basin reflects among other aspects also the importance and the need of international co-operation at various levels. The response of this need has been expressed by the formation of different international commissions and organisations in the basin, covering mainly technical but in the recent time also the environmental interests of the riparian states. The Danube countries, several G-24 governments, as well as international and non governmental organisations decided in the autumn of 1991 to start the Environmental Programme for the Danube River Basin (EPDRB) and form the Danube Task Force. A joint Programme work plan was agreed by the Task Force in February 1992, thereby launching a series of priority projects designed to built environmental co-operation among the Danube countries. The main objective was to establish an operational basis for strategic and integrated management of the Danube river basin environment. The planning and working documents, which were outlining the activities within the EPDRB are the Strategic Action Plan (SAP-1994) and the Strategic Action Plan Implementation Programme (SIP-1996). These documents frame the works of the 13 Tasks of the Applied Research Programme, Sub-Groups of the Accident Emergency Warning System, Monitoring, Laboratories and Information Management and Data Management as well as the major areas of work, divided in Groups and Clusters, each of which will involve projects to be carried out in a number of Danube countries. All activities are oriented to the improvement of the environment, however special attention is paid to task dealing with biodiversity, wetlands restoration, water and soil protection. The main funding, which is secured until the year 2000 comes from the Danube countries, the EU Phare and Tacis programmes, the UN GEF, international banks and foundations. (author)

  10. Liquor Activity Reduction (LAR) Programme - 12397

    Waste material from the reprocessing of irradiated fuel has been stored under water for several decades leading to the water becoming highly radioactive. As a critical enabler to the decommissioning strategy for the Sellafield site, the Liquor Activity Reduction (LAR) programme has been established to provide a processing route for this highly radioactive liquor. This paper reviews the progress that has been made since the start of routine LAR transfer cycles (July 2010) and follows on from the earlier paper presented at WM2011. The paper focuses on the learning from the first full year of routine LAR transfer cycles and the application of this learning to the wider strategies for the treatment of further radioactive liquid effluents on the Sellafield site. During this period over 100,000 Curies of radioactivity has been safely removed and treated. The past year has witnessed the very successful introduction of the LAR programme. This has lead to hazard reduction at MSSS and demonstration that the SIXEP facility can meet the significantly increased challenge that the LAR programme represents. Part of the success has been the ability to predict and deliver a realistic production schedule with the availability of the MSSS, EDT and SIXEP facilities being central to this. Most importantly, the LAR programme has been successful in bringing together key stakeholders to deliver this work while integrating with the existing, day to day, demands of the Sellafield site. (authors)

  11. Liquor Activity Reduction (LAR) Programme - 12397

    Pether, Colin; Carrol, Phil; Birkett, Eddie; Kibble, Matthew [Sellafield Ltd, Cumbria (United Kingdom)

    2012-07-01

    Waste material from the reprocessing of irradiated fuel has been stored under water for several decades leading to the water becoming highly radioactive. As a critical enabler to the decommissioning strategy for the Sellafield site, the Liquor Activity Reduction (LAR) programme has been established to provide a processing route for this highly radioactive liquor. This paper reviews the progress that has been made since the start of routine LAR transfer cycles (July 2010) and follows on from the earlier paper presented at WM2011. The paper focuses on the learning from the first full year of routine LAR transfer cycles and the application of this learning to the wider strategies for the treatment of further radioactive liquid effluents on the Sellafield site. During this period over 100,000 Curies of radioactivity has been safely removed and treated. The past year has witnessed the very successful introduction of the LAR programme. This has lead to hazard reduction at MSSS and demonstration that the SIXEP facility can meet the significantly increased challenge that the LAR programme represents. Part of the success has been the ability to predict and deliver a realistic production schedule with the availability of the MSSS, EDT and SIXEP facilities being central to this. Most importantly, the LAR programme has been successful in bringing together key stakeholders to deliver this work while integrating with the existing, day to day, demands of the Sellafield site. (authors)

  12. Kissing spines: fact or fancy?

    Beks, J W

    1989-01-01

    In the Neurosurgical Clinic in Groningen 64 patients underwent surgery between 1975 and 1985 for a clinical and radiological syndrome described by Baastrup in 1933 and called in the Anglo-saxon literature: "kissing spines". Because the results of the surgical treatment were disappointing we submitted these results to further analysis. PMID:2589119

  13. KEK in Riken. KISS project and KEK Wako Nuclear Science Center

    Aim of the KEK KISS project is to understand an astrophysical origin of the rapid neutron capture process through the decay studies of unknown nuclei having the mass number around 195 and the neutron number around 126 in so called blank spot region, where has been hard to access experimentally, so far. We have developed a new experimental method consisting of multi-nucleon transfer reactions of neutron-rich heavy-ion beams and a mass separator combined with an element selective laser resonance ionization. This device is named as KEK Isotope Separation System (KISS). After the success of the developments, KISS will be open for users in this year as one of experimental apparatuses in the RIBF facility of Riken Nishina Center. And a KEK new branch, Wako Nuclear Science Center (WNSC) has been launched at Riken Wako campus from this April for supporting the scientific activities of KISS users. (author)

  14. Kissing in the Shadow

    Paul Thomas

    2013-05-01

    Full Text Available 28 August, Newtown, Sydney: following an encounter the day prior at the National Institute for Experimental Arts, they meet again. A fluid discussion around art, perception, philosophy, vision, probabilities, and physics resulted—transforming into an activity of mobile phone photography—a photo-walk, a means of engaging with the world. The walk down King Street is a visual discussion, collected observations of things noted, a probability map, and a becoming, “like the emergence of another world.”

  15. Graduate nuclear engineering programmes motivate educational and research activities

    Some fifteen years ago the University of Ljubljana, Faculty for Mathematics and Physics together with the national research organisation the J. Stefan jointly established a Graduate programme of Nuclear Engineering. From the onset, the programme focused on nuclear technology, nuclear safety, and reactor physics and environment protection. Over the years this graduate programme has became the focal point of nuclear related, research and educational activities in Slovenia. It has grown into a meeting ground for recognised national and distinguished foreign educators and experienced professionals from the industry. In conjunction with an important national project, supported by the Slovenian government, entitled 'Jung Researcher' it also enhances the knowledge transfer to the next generation. Since the programme was introduced, the interest for this programme has been steadily growing. Accordingly, a number of PhD and MS degrees in NE have been awarded. The graduates of this programme have encountered very good job opportunities in nuclear as well as in non-nuclear sector. (author)

  16. Costs and benefits of Danish active labour market programmes

    Jespersen, Svend; Munch, Jakob Roland; Skipper, Lars

    2008-01-01

    Since 1994, unemployed workers in the Danish labour market have participated in active labour market programmes on a large scale. This paper contributes with an assessment of costs and benefits of these programmes. Long-term treatment effects are estimated on a very detailed administrative dataset...

  17. Delimiting Maximal Kissing Configurations in Four Dimensions

    Altschuler, Eric Lewin

    2013-01-01

    How many unit $n-$dimensional spheres can simultaneously touch or kiss a central $n-$dimensional unit sphere? Beyond mathematics this question has implications for fields such as cryptography and the structure of biologic and chemical macromolecules. The kissing number is only known for dimensions 1-4, 8 and 24 (2, 6, 12, 24, 240, 19650, respectively) and only particularly obvious for dimensions one and two. Indeed, in four dimensions it is not even known if Platonic polytope unique to that dimension known as the 24-cell is the unique kissing configuration. We have not been able to prove that the 24-cell is unique, but, using a physical approach utilizing the hopf map from four to three dimensions, we for the first time delimit the possible other configurations which could be kissing in four dimensions.

  18. Diversity Programme Activity Report 2012-2015

    Guinot, Genevieve; CERN. Geneva. HR Department

    2016-01-01

    CERN’s Diversity programme was launched in 2012 and is now firmly established as one of the pillars of the Organization’s Human Resources strategy. This report provides information on the actions undertaken in pursuit of the seven diversity strategic objectives set for the period from 2012 to 2015 in the priority areas identified for actions of recruitment, career development and work environment. The report highlights the progress made in anchoring the diversity principles in policies, procedures and practices within the Organization, as well as the persistent difficulties for the Organization to improve the representation of some nationalities and to attract female applicants in science and engineering. It shows a constant increase of female representation in managerial positions and encouraging results in building a diverse talent pool of scientists and engineers through the various student and graduate programmes. The report also outlines how the Diversity Office contributed through several actions,...

  19. The European Commission Cooperative Support Programme: Activities and Achievements

    Goncalves, Joao; ABOUSAHL Said; FRIGOLA PIERRE

    2010-01-01

    The IAEA bases its technical and scientific Programme on contributions from the Member State Support Programmes (MSSP). The European Commission Cooperative Support Programme (EC-SP) started in 1981 to support IAEA¿s activities in the field of nuclear safeguards. Since its beginning, the EC-SP has been operated by the European Commission¿s Joint Research Centre (JRC) and its institutes at Ispra-Italy, Geel-Belgium and Karlsruhe-Germany. The EC-SP tasks provide technology and expertise in many ...

  20. Halden IASCC programme activities for 1996

    This report describes two new investigations on IASCC, which begin in 1996. In one of the investigations (IFA 618) the initiation of cracks in pressurised tube specimens prepared from common structural component materials 304, 316 and 347 SS is being studied as function of stress level and fluence. In the second investigation (IFA 612) the benefits of hydrogen additions in suppressing crack growth also in materials with high accumulated fluence are addressed. Bellows loaded Compact Tension specimens, fabricated from irradiated 304 and 347 SS, and instrumented for in-pile crack growth monitoring are being used in the study. Also described are plans for the validation of miniaturised three point bend specimens which are expected to be used in the future test programme together with already qualified crack growth sensors and the evaluation of the electrochemical noise technique which is to be used in conjunction with pressurised tube specimens in crack initiation studies. (author)

  1. Overexpression of KiSS-1 reduces colorectal cancer cell invasion by downregulating MMP-9 via blocking PI3K/Akt/NF-κB signal pathway.

    Chen, Shaoqin; Chen, Wei; Zhang, Xiang; Lin, Suyong; Chen, Zhihua

    2016-04-01

    Metastasis of colorectal cancer (CRC) depends critically on MMP-9. KiSS-1 is a human malignant melanoma metastasis-suppressor gene. Thus, the interaction between MMP-9 and KiSS-1 has drawn considerable attention in recent years. In the present study, it was hypothesized that KiSS-1 gene could repress the metastatic potential of colorectal cancer cells by inhibiting the expression of MMP-9. Stable transfection of KiSS-1 specific siRNA and KiSS-1 expression vector in human CRC cell line HCT-116 was achieved by lentivirus infection. Moreover, the cell proliferation, invasiveness, and apoptosis were evaluated by CCK-8 method, transwell experiment, and fluorescence activated cell sorter, respectively. We also investigated the expression of MMP-9, PI3K, Akt, pAKt, and NF-кB subunit p65 using western blotting. KiSS-1 overexpression significantly decreased the cell proliferation and invasiveness of HCT-119 cells, while apoptosis was enhanced. The result of western blotting showed that synthesis of MMP-9, PI3K, p65, and phosphorylation of Akt were significantly blocked by overexpression of KiSS-1. Concatenated treatment of KiSS-1 overexpression vector with PI3K and Akt agonists attenuated the effect of KiSS-1 on the biological activity of CRC cells and also released the expression of MMP-9, PI3K, p65, and phosphorylation of Akt from the influence of overexpression of KiSS-1. Overexpression of KiSS-1 suppressed the invasiveness of CRC cells, and the gene exerted its function by reducing the expression of MMP-9 via blocking of tge PI3K/Akt/NF-κB pathway. PMID:26847533

  2. Kissing osteochondromata leading to synostoses.

    Bessler, W; Eich, G; Stuckmann, G; Zollikofer, C

    1997-01-01

    Our aim was to determine the incidence of synostoses in the bones of the lower limbs in patients with multiple cartilaginous exostosis (MCE) and use the available imaging to suggest the cause and mechanism of its development. Radiographs of the lower legs of 21 patients with MCE were reviewed. With the intention of demonstrating the exact site and extent of synostoses and other bone deformities, such as bone pressure atrophy or erosions in five patients, 8 proximal and 6 distal tibiofibular joints were examined by CT scans. No synostoses were present in 11 patients and 10 patients had 1 to 4 synostoses. Of these synostoses, 14 were localized below the knee joint and 9 above the ankle joint. A growing osteochondroma arising from tibia or fibula can cause an erosion in the contagious surface of the neighbouring bone. If facing osteochondromata are present in both bones and show an interlocking growth at abutting parts, on osseous fusion can take place with formation of a synostosis in the proximal or distal tibiofibular joint region. In adult patients with MCE and abundant osteochondromata synostoses between the neighbouring bones of the lower legs are common findings; they are always caused by coalescence of "kissing" osteochondromata. PMID:9204324

  3. Biennial activity report of Metallurgy Programme - 1985 and 1986

    The biennial activity report of the Metallurgy Programme of the Indira Gandhi Centre for Atomic Research covers the period of the years 1985 and 1986. Along with NDT, welding metallurgy, low cycle fatigue, creep and creep fatigue interactions, structure-property correlations, thermodynamics and corrosion metallurgy of alloy steels with respect to their compatibility with aqueous and liquid sodium environments continue to be the major thrust areas of the Programme. Some of the basic research contributions of the Programme are: the observation of uniform and homogeneous distribution of voids in cyclically deformed 304 SS, the role of grain boundaries and precipitation in dynamic strain ageing of 316 SS and the determination of the activities of component metals in 316 and 304 SS by metastable EMF method. (author)

  4. Differential regulation of kiss1 expression by melatonin and gonadal hormones in male and female Syrian hamsters

    Ansel, L; Bolborea, M; Bentsen, A H;

    2010-01-01

    In seasonal breeders, reproduction is synchronized to seasons by day length via the pineal hormone melatonin. Recently, we have demonstrated that Kiss1, a key activator of the reproductive function, is down-regulated in sexually inactive hamsters maintained in inhibitory short days (SDs). In...... rodents, Kiss1 is expressed in the anteroventral periventricular nucleus (AVPV) and in the arcuate nucleus (ARC). Because both the duration of the nocturnal peak of melatonin and circulating sex steroid levels vary with photoperiod, the aim of this study was to determine whether melatonin and sex steroids...... as compared to LD animals, 2) sex steroid treatment in SD-adapted male and female hamsters increased the numberof Kiss1 neurons in the AVPV but decreased it in the ARC, 3) melatonin administration to LD-adapted hamsters decreased Kiss1 mRNA level in both the AVPV and the ARC in intact animals...

  5. The European Commission Cooperative Support Programme: Activities and Cooperation

    The International Atomic Energy Agency (IAEA) bases its technical and scientific programme on voluntary contributions from Member States, constituting the Member States Support Programme (MSSP). The European Commission Cooperative Support Programme (EC-SP) started in 1981 to support IAEA activities in the field of nuclear safeguards. Since its beginning, the EC-SP has been operated by the European Commission's Joint Research Centre in close collaboration and coordination with the European Commission's Directorate General for Energy-Directorate Nuclear Safeguards implementing the Euratom treaty. EC-SP tasks provide technology and expertise in technical areas related to the effective implementation of safeguards verification measures including the detection of undeclared materials, activities, and facilities. The EC-SP fosters cooperation with Support Programmes from European Union Member States, as well as with non-EU states with which the European Commission has specific research and development agreements, e.g., the United States Department of Energy, ABACC. Information on the research and development activities under these frameworks is shared with the IAEA and complements core EC-SP work. The paper describes the EC-SP, its modus operandi, collaborations, and main activities, namely, (a) the specific R&D work as part of tasks with well-defined milestones and deadlines, (b) training activities; (c) the technical support in establishing Safeguards guidelines and approaches and (d) the technical consultancy support to IAEA meetings and expert groups. (author)

  6. Research reactor activities in support of national nuclear programmes

    This report is the result of an IAEA Technical Committee Meeting on Research Reactor Activities in Support of National Nuclear Programmes held in Budapest, Hungary during 10-13 December 1985. The countries represented were Belgium, Finland, France, Federal Republic of Germany, German Democratic Republic, India, Poland, Spain, United Kingdom, United States, Yugoslavia and Hungary. The purpose of the meeting was to present information and details of several well-utilized research reactors and to discuss their contribution to national nuclear programmes. A related Agency activity, a Seminar on Applied Research and Service Activities for Research Reactor Operations was held in Copenhagen, Denmark during 9-13 September 1985. Selected papers from this Seminar relevant to the topic of research reactor support of national nuclear programmes have been included in this report. A separate abstract was prepared for each of 19 papers presented at the Technical Committee Meeting on Research Reactor Activities in Support of National Nuclear Programmes and for each of 15 papers selected from the presentations of the Seminar on Applied Research and Service Activities for Research Reactor Operations

  7. Primer on CDM programme of activities

    Hinostroza, M. (UNEP Risoe Centre, Roskilde (Denmark)); Lescano, A.D. (A2G Carbon Partners (Peru)); Alvarez, J.M. (Ministerio del Ambiente del Peru (Peru)); Avendano, F.M. (EEA Fund Management Ltd. (United Kingdom)

    2009-07-01

    As an advanced modality introduced in 2005, the Programmatic CDM (POA) is expected to address asymmetries of participation, especially of very small-scale project activities in certain areas, key sectors and many countries with considerable potential for greenhouse gas emission reductions, not reached by the traditional single-project-based CDM. Latest experiences with POAs and the recently finalized official guidance governing the Programmatic CDM are the grassroots of this Primer, which has the purpose of supporting the fully understanding of rules and procedures of POAs by interpreting them and analyzing real POA cases. Professional and experts from the public and private entities have contributed to the development of this Primer, produced by the UNEP Risoe Centre, as part of knowledge support activities for the Capacity Development for the CDM (CD4CDM) project. The overall objective of the CD4CDM is to develop the capacities of host countries to identify, design, approve, finance, implement CDM projects and commercialize CERs in participating countries. The CDM4CDM is funded by the Netherlands Ministry of Foreign Affairs. (author)

  8. Technical Support Activities of a Nuclear Materials Management Programme

    The development of a nuclear materials management programme in the United States of America has recognized from its inception the value and need of strong technical support. The success of that programme has depended to a large extent on the development of a closely allied technical support effort. This effort has drawn on the technical competency of top governmental, industrial and academic consultants, in addition to that within the USAEC. Under the planning, development and administration of the USAEC's Division of Nuclear Materials Management, a broad spectrum of technical activities has evolved. These include: (a) The establishment of an Advisory Committee for Standard Reference Materials and Methods of Measurement, (b) Preparation and USAEC co-ordination with the National Bureau of Standards in the development of a series of uranium and plutonium chemical and isotopic standards, (c) Research and development programmes designed to provide improved measurement techniques, (d) Compilation and publication of a book of selected measurement methods for uranium and plutonium. Each of these technical support activities is discussed in some detail, including the conditions that gave rise to their need and development, and their application to the USAEC's nuclear materials management programme. Included is a discussion of the USAEC's Advisory Committee for Standard Reference Materials and Methods of Measurement, which was established to provide guidance to the nuclear materials management programme and recommend research and development activities. Resulting from these recommendations was a USAEC co-operative effort with the National Bureau of Standards for the development of chemical and isotopic standard reference materials of uranium and plutonium; particular attention is devoted to the results of that joint effort. The need for research and development efforts in areas of mutual interest is examined, and the cooperation of other nations of the world is elicited in

  9. Examining the possible functions of kissing in romantic relationships

    Wlodarski,Rafael; Dunbar, Robin I. M.

    2013-01-01

    Recent research suggests that romantic kissing may be utilized in human sexual relationships to evaluate aspects of a potential mate’s suitability, to mediate feelings of attachment between pair-bonded individuals, or to facilitate arousal and initiate sexual relations. This study explored these potential functions of romantic kissing by examining attitudes towards the importance of kissing in the context of various human mating situations. The study involved an international online questionn...

  10. No Kiss1ng by leptin during puberty?

    Ahima, Rexford S.

    2010-01-01

    Leptin exerts a permissive action on puberty by stimulating release of gonadotropin-releasing hormone (GnRH) in the hypothalamus. However, GnRH neurons lack leptin receptor (LepR), indicating that leptin must indirectly regulate these neurons. The Kiss1 gene produces kisspeptins that stimulate GnRH secretion. Because Kiss1 neurons express LepR and inactivation of Kiss1 causes hypogonadotropic hypogonadism, Donato et al., in this issue of the JCI, assessed whether deletion of LepR from Kiss1 n...

  11. Recent Activities on the Experimental Research Programme Using Small Tokamaks

    A new concept of interactive co-ordinated research using small tokamaks in the mainstream fusion science areas, in testing of new diagnostics, materials and technologies as well as in education, training and broadening of the geography of fusion research in the scope of the IAEA Co-ordinated Research Project (CRP) is discussed in this paper. Besides the presentation of the recent activities on the experimental research programme using small tokamaks and scientific results achieved at the participating laboratories, information is provided about the organisation of the co-ordinated research project. Future plans of the co-ordinated activities within the CRP are discussed

  12. Kiss-induced severe anaphylactic reactions

    Atanasković-Marković Marina

    2010-01-01

    Full Text Available Introduction. Ingestion is the principal route for food allergens to trigger allergic reaction in atopic persons. However, in some highly sensitive patients severe symptoms may develop upon skin contact and by inhalation. The clinical spectrum ranges from mild facial urticaria and angioedema to life-threatening anaphylactic reactions. Outline of Cases. We describe cases of severe anaphylactic reactions by skin contact, induced by kissing in five children with prior history of severe anaphylaxis caused by food ingestion. These cases were found to have the medical history of IgE mediated food allergy, a very high total and specific serum IgE level and very strong family history of allergy. Conclusion. The presence of tiny particles of food on the kisser's lips was sufficient to trigger an anaphylactic reaction in sensitized children with prior history of severe allergic reaction caused by ingestion of food. Allergic reaction provoked with food allergens by skin contact can be a risk factor for generalized reactions. Therefore, extreme care has to be taken in avoiding kissing allergic children after eating foods to which they are highly allergic. Considering that kissing can be a cause of severe danger for the food allergic patient, such persons should inform their partners about the risk factor for causing their food hypersensitivity.

  13. Issues related to a programme of activities under the CDM

    Ellis, J.

    2006-05-15

    Emissions of CO2 from the energy and land-use change and forestry sectors are responsible for the majority of emissions in non-Annex I Parties to the UNFCCC. Tackling greenhouse gas (GHG) emissions from these sectors is a key to slowing the growth in GHG emissions in non-Annex I countries. Implementing Clean Development Mechanism (CDM) projects can help achieve this aim, while also assisting non-Annex I countries to move towards sustainable development and Annex I countries achieve their emission commitments under the Kyoto Protocol. There has been rapid progress in the CDM over the last year - in terms of the number of projects in the pipeline and registered, and in terms of credits issued. However, some important sectors are notable by their small share in the CDM portfolio. Several countries have also called attention to the need to accelerate the process of approving CDM methodologies and projects. In order to improve the effectiveness of the CDM to achieve its dual objectives, the COP/MOP agreed a decision on 'further guidance relating to the clean development mechanism. This decision lays out guidance on how to improve the operation of the CDM, and includes provisions that allow: (1) Bundling of project activities; and (2) Project activities under a programme of activities, to be registered as a CDM project activity. At present, of the 172 currently registered CDM project activities, 27 involve programmes or bundles. These project activities can include more than one project type, be implemented in several locations, and/or occur in more than one sector. This paper assesses how project activities under a programme of activities under the CDM (referred to here as PCDM) could help to increase the effectiveness of the CDM by encouraging a wide spread of emission mitigation activities. This paper also explores the key issues that may need to be considered for the PCDM concept to be further implemented. The paper concludes that: (1) Key concepts and issues

  14. Active-Pixel Image Sensors With Programmable Resolution

    Kemeny, Sabrina E.; Fossum, Eric R.; Pain, Bedabrata; Nakamura, Junichi; Matthies, Larry H.

    1996-01-01

    Active-pixel image sensors with programmable resolution proposed for use in applications in which speed and efficiency of processing of image data enhanced by providing those data at varying resolutions. Such applications include modeling of biological vision, stereoscopic range-finding, recognition of patterns, tracking targets, and progressive transmission of compressed images. In target-tracking application, sensor initially forms low-resolution image from which area of interest identified, then sensor set at high resolution for examination of identified area. Outputs of contiguous pixels combined. Sensor of this type made to act as though it comprised fewer and larger pixels.

  15. The Role of Neurotransmitters in Protection against Amyloid- β Toxicity by KiSS-1 Overexpression in SH-SY5Y Neurons.

    Chilumuri, Amrutha; Milton, Nathaniel G N

    2013-01-01

    Recent studies have suggested that the kisspeptin (KP) and kissorphin (KSO) peptides have neuroprotective actions against the Alzheimer's amyloid- β (A β ) peptide. Overexpression of the human KiSS-1 gene that codes for KP and KSO peptides in SH-SY5Y neurons has also been shown to inhibit A β neurotoxicity. The in vivo actions of KP include activation of neuroendocrine and neurotransmitter systems. The present study used antagonists of KP, neuropeptide FF (NPFF), opioids, oxytocin, estrogen, adrenergic, cholinergic, dopaminergic, serotonergic, and γ -aminobutyric acid (GABA) receptors plus inhibitors of catalase, cyclooxygenase, nitric oxide synthase, and the mitogen activated protein kinase cascade to characterize the KiSS-1 gene overexpression neuroprotection against A β cell model. The results showed that KiSS-1 overexpression is neuroprotective against A β and the action appears to involve the KP or KSO peptide products of KiSS-1 processing. The mechanism of neuroprotection does not involve the activation of the KP or NPFF receptors. Opioids play a role in the toxicity of A β in the KiSS-1 overexpression system and opioid antagonists naloxone or naltrexone inhibited A β toxicity. The mechanism of KiSS-1 overexpression induced protection against A β appears to have an oxytocin plus a cyclooxygenase dependent component, with the oxytocin antagonist atosiban and the cyclooxygenase inhibitor SC-560 both enhancing the toxicity of A β . PMID:24967306

  16. Till surgery do us part: unexpected bilateral kissing molars

    Narayanankutty Anish

    2015-02-01

    Full Text Available The occurrence impacted teeth, single or multiple is very common. But, phenomenon of kissing molars is an extremely rare phenomenon. Mandibular third molars are the most common impacted teeth. Mandibular first or second molars does not share the same frequency of occurrence. But, there are rare cases in which the occlusal surfaces of impacted molars are united by the same follicular space and the roots point in the opposite direction, and are termed as kissing molars. Sometimes, these teeth will be associated with pathologies. This article reports a rare case of mandibular bilateral kissing molars.

  17. Stability analysis of active acoustic metamaterial with programmable bulk modulus

    Acoustic metamaterials (AMMs) have been considered as an effective means of controlling the propagation of acoustical wave energy through metamaterials. However, most of the currently exerted efforts are focused on studying passive metamaterials with fixed material properties. In this paper, the emphasis is placed on the development of a new class of one-dimensional acoustic metamaterials with effective bulk moduli that are programmed to vary according to any prescribed pattern along the volume of the metamaterial. Acoustic cavities coupled with either actively controlled Helmholtz or flush-mounted resonators are introduced to develop two possible configurations for obtaining active AMMs (AAMMs) with programmable bulk modulus capabilities. The resonators are provided with piezoelectric boundaries to enable control of the overall bulk modulus of the acoustic cavity through direct acoustic pressure feedback. Theoretical analyses of these two configurations of AAMMs are presented using the lumped-parameter modeling approach. The presented analyses are utilized to study the stability characteristics of the two configurations in an attempt to define their stable regions of operation. Numerical examples are presented to demonstrate the performance characteristics of the proposed AAMM configurations and their potential for generating prescribed spatial and spectral patterns of bulk modulus variation

  18. Active Labour Market Programmes and Unemployment in a Dual Labour Market

    Fukushima, Yoshihiko

    1998-01-01

    The paper presents a theoretical analysis of the macroeconomic effects of active labour market programmes in a dual labour-market framework. The paper uses the Shapiro-Stiglitz efficiency-wage model. Active labour market programmes train unskilled labour and transfer them from a high-unemployment to a low-unemployment sector. Programmes have a direct labour-transfer effect which tends to reduce total unemployment. They also have effects on wages via expectations. The later effects were to a v...

  19. Baastrup’s disease: The kissing spine

    Singla, Amit; Shankar, Vivek; Mittal, Samarth; Agarwal, Abhinav; Garg, Bhavuk

    2014-01-01

    A 67-year-old male presented with a gradually progressive low back pain of 2 years duration. The patient was leading a retired life and there was no history of chronic fever or significant trauma. There was no radiation of pain or any features suggestive of claudication. There was no history of any comorbidity. The pain was aggravated with extension of the spine and relieved with flexion. There was no swelling or neurological deficit, but muscle spasm was present. Radiographs of the spine revealed degenerative changes in the lumbosacral spine, along with articulation of spinous processes at in lumbar spine at all levels level suggestive of Baastrup’s disease, commonly known as “kissing spine”. Routine blood investigations were within normal limits. The patient was managed conservatively. He was given a week’s course of analgesics and muscle relaxants and then started on spinal flexion exercises, with significant improvement being noted at 6 months follow up. PMID:24579072

  20. Kissing reduces allergic skin wheal responses and plasma neurotrophin levels.

    Kimata, Hajime

    2003-11-01

    The effect of kissing on allergen-induced skin wheal responses and plasma neurotrophin levels were studied in 30 normal subjects, 30 patients with allergic rhinitis (AR), and 30 patients with atopic dermatitis (AD). All of the patients with AR or AD are allergic to house dust mite (HDM) and Japanese cedar pollen (JCP). They are all Japanese and they do not kiss habitually. The subject kissed freely during 30 min with their lover or spouse alone in a room with closed doors while listening to soft music. Before and after kissing, skin prick tests were performed using commercial HDM allergen, JCP allergen, as well as histamine and control solution, and wheal responses were measured. Simultaneously, plasma levels of neurotrophin, including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and -4 (NT-4) were measured. Kissing significantly reduced wheal responses induced by HDM and JCP, but not by histamine, and decreased plasma levels of NGF, BDNF, NT-3, and NT-4 in patients with AR or AD, while it failed to do so in normal subjects. These finding indicate that kissing have some implication in the study of neuroimmunology in allergic patients. PMID:14637240

  1. Programme Costing of a Physical Activity Programme in Primary Prevention: Should the Costs of Health Asset Assessment and Participatory Programme Development Count?

    Silke B. Wolfenstetter

    2012-01-01

    Full Text Available This analysis aims to discuss the implications of the “health asset concept”, introduced by the WHO, and the “investment for health model” requiring a “participatory approach” of cooperative programme development applied on a physical activity programme for socially disadvantaged women and to demonstrate the related costing issues as well as the relevant decision context. The costs of programme implementation amounted to €48,700. Adding the costs for developing the programme design of €48,800 results in total costs of €97,500; adding on top of that the costs of asset assessment running to €35,600 would total €133,100. These four different cost figures match four different types of potentially relevant decisions contexts. Depending on the decision context the total costs, and hence the incremental cost-effectiveness ratio of a health promotion intervention, could differ considerably. Therefore, a detailed cost assessment and the identification of the decision context are of crucial importance.

  2. Adult Workers in Theory or Practice? : Lone Mothers’ Participation in Active Labour Market Programmes in Germany

    Cordula Zabel

    2015-01-01

    This paper examines lone mothers’ participation in active labour market programmes in Germany. Since the 2005 Hartz IV employment and welfare policy reforms, expectations that non-em- ployed parents receiving means-tested benefits should be ready for employment or labour market programme participation have grown stronger. However, discretion for programme assignments is left to individual caseworkers. As a consequence, it is not clear to what extent the formal policy orientation towards an ad...

  3. Reason and Condition for Mode Kissing in MASW Method

    Gao, Lingli; Xia, Jianghai; Pan, Yudi; Xu, Yixian

    2016-05-01

    Identifying correct modes of surface waves and picking accurate phase velocities are critical for obtaining an accurate S-wave velocity in MASW method. In most cases, inversion is easily conducted by picking the dispersion curves corresponding to different surface-wave modes individually. Neighboring surface-wave modes, however, will nearly meet (kiss) at some frequencies for some models. Around the frequencies, they have very close roots and energy peak shifts from one mode to another. At current dispersion image resolution, it is difficult to distinguish different modes when mode-kissing occurs, which is commonly seen in near-surface earth models. It will cause mode misidentification, and as a result, lead to a larger overestimation of S-wave velocity and error on depth. We newly defined two mode types based on the characteristics of the vertical eigendisplacements calculated by generalized reflection and transmission coefficient method. Rayleigh-wave mode near the kissing points (osculation points) change its type, that is to say, one Rayleigh-wave mode will contain different mode types. This mode type conversion will cause the mode-kissing phenomenon in dispersion images. Numerical tests indicate that the mode-kissing phenomenon is model dependent and that the existence of strong S-wave velocity contrasts increases the possibility of mode-kissing. The real-world data shows mode misidentification caused by mode-kissing phenomenon will result in higher S-wave velocity of bedrock. It reminds us to pay attention to this phenomenon when some of the underground information is known.

  4. Earth observation space programmes, SAFISY activities, strategies of international organisations, legal aspects. Volume 3

    This volume is separated in four sessions. First part is on earth observation space programmes (international earth observation projects and international collaboration, the ERS-1, SPOT and PRIRODA programmes, the first ESA earth observation polar platform and its payload, the future earth observation remote sensing techniques and concepts). The second part is on SAFISY activities (ISY programmes, education and applications, demonstrations and outreach projects). The third part is on programme and strategies of international organisations with respect to earth observation from space. The fourth part is on legal aspects of the use of satellite remote sensing data in Europe. (A.B.). refs., figs., tabs

  5. A telecare programme for self-management of COPD exacerbations and promotion of an active lifestyle

    Tabak, Monique; Brusse-Keizer, Marjolein; Ommeren, Clara; Kotte, Hayke; Weltevreden, Paul; Hermens, Hermie; Vollenbroek-Hutten, Miriam

    2013-01-01

    Objective: The Condition Coach (CoCo) is a technology-supported care programme for self-management of COPD exacerbations and for promotion of an active lifestyle. The objective is to investigate the added value of the telecare programme in terms of clinical changes compared to usual care, and in add

  6. Kissing nevus of the penis. Report of two cases and review of the literature *

    Wang, Songting; Zhou, Mingshu; Qiao, Jianjun

    2014-01-01

    Kissing nevus is a curious type of nevus that was first described on the eyelids and rarely described on the penis. We report two cases of kissing nevus of the penis and review previously reported cases. The lesions of the kissing nevus of the penis showed characteristic mirror-image symmetry relative to the coronal sulcus. On histopathology, the lesion showed a compound nevus.

  7. Applying a nonlinear, pitch-catch, ultrasonic technique for the detection of kissing bonds in friction stir welds.

    Delrue, Steven; Tabatabaeipour, Morteza; Hettler, Jan; Van Den Abeele, Koen

    2016-05-01

    Friction stir welding (FSW) is a promising technology for the joining of aluminum alloys and other metallic admixtures that are hard to weld by conventional fusion welding. Although FSW generally provides better fatigue properties than traditional fusion welding methods, fatigue properties are still significantly lower than for the base material. Apart from voids, kissing bonds for instance, in the form of closed cracks propagating along the interface of the stirred and heat affected zone, are inherent features of the weld and can be considered as one of the main causes of a reduced fatigue life of FSW in comparison to the base material. The main problem with kissing bond defects in FSW, is that they currently are very difficult to detect using existing NDT methods. Besides, in most cases, the defects are not directly accessible from the exposed surface. Therefore, new techniques capable of detecting small kissing bond flaws need to be introduced. In the present paper, a novel and practical approach is introduced based on a nonlinear, single-sided, ultrasonic technique. The proposed inspection technique uses two single element transducers, with the first transducer transmitting an ultrasonic signal that focuses the ultrasonic waves at the bottom side of the sample where cracks are most likely to occur. The large amount of energy at the focus activates the kissing bond, resulting in the generation of nonlinear features in the wave propagation. These nonlinear features are then captured by the second transducer operating in pitch-catch mode, and are analyzed, using pulse inversion, to reveal the presence of a defect. The performance of the proposed nonlinear, pitch-catch technique, is first illustrated using a numerical study of an aluminum sample containing simple, vertically oriented, incipient cracks. Later, the proposed technique is also applied experimentally on a real-life friction stir welded butt joint containing a kissing bond flaw. PMID:26921559

  8. Combustion chemistry - activities in the CHEK research programme

    Dam-Johansen, K.; Johnsson, J.E.; Glarborg, P.; Frandsen, F.; Jensen, A.; Oestberg, M. [Technical Univ. of Denmark, Lyngby (Denmark). Dept. of Chemical Engineering

    1997-10-01

    The combustion chemistry in the oxidation of fossil fuels and biofuels determines together with mixing and heat transfer the required size of a furnace, the emission of gaseous pollutants, and the formation of ash and deposits on surfaces. This presentation describes technologies for solid fuels combustion and gives a summary of the fuels, the pollutant chemistry and the inorganic chemistry in combustion processes. Emphasis is put on the work carried out in the CHEC (Combustion and Harmful Emission Control) Research Programme. (orig.)

  9. The Effect of Sanctions and Active Labour Market Programmes on the Exit Rate From Unemployment

    Ahmad, Nisar; Svarer, Michael

    2009-01-01

    ). Hence, modeling only one of them as treatment might over or underestimate the true effect. Therefore, by using a multivariate mixed proportional hazard model (MMPH), we model the hazard rate out of unemployment along with the sanction rate and hazard rate into active labour market programmes. We......This paper simultaneously investigates the effectiveness of benefit sanctions and active labour market programmes on the exit rate from unemployment using Danish data. In the data about one third of the individuals who are sanctioned also participate in some active labour market programmes (ALMPs...... optimally select the number of supports point for the distribution of unobserved heterogeneity. Results show that pre-specifying two support points underestimates the effect of sanctions and active labour market programmes. Failing to control for selectivity for sanctions not only underestimates the...

  10. The Effect of Sanctions and Active Labour Market Programmes on the Exit Rate From Unemployment

    Ahmad, Nisar; Svarer, Michael

    ). Hence, modeling only one of them as treatment might over or underestimate the true effect. Therefore, by using a multivariate mixed proportional hazard model (MMPH), we model the hazard rate out of unemployment along with the sanction rate and hazard rate into active labour market programmes. We......This paper simultaneously investigates the effectiveness of benefit sanctions and active labour market programmes on the exit rate from unemployment using Danish data. In the data about one third of the individuals who are sanctioned also participate in some active labour market programmes (ALMPs...... optimally select the number of supports point for the distribution of unobserved heterogeneity. Results show that pre-specifying two support points underestimates the effect of sanctions and active labour market programmes. Failing to control for selectivity for sanctions not only underestimates the...

  11. Factors affecting uptake of an education and physical activity programme for newly diagnosed type 2 diabetes.

    Visram, S.; Bremner, A.S.; Harrington, B.E.; Hawthorne, G

    2008-01-01

    Background: Intensive lifestyle intervention involving weight reduction and moderate physical activity has been shown to help regulate, and even prevent, type 2 diabetes. Aim: This study sought to explore factors affecting uptake of an education and physical activity programme for those diagnosed with type 2 diabetes. Method: Focus group discussions were conducted with individuals who completed the programme and semi-structured interviews were conducted with those who decline...

  12. From activity to learning: using cultural historical activity theory to model school library programmes and practices

    E.M. Meyers

    2007-01-01

    Full Text Available Introduction. changes in educational policy and practice demand that we examine school library programmes from a new perspective. As a model that takes a developmental view of minds in context, Cultural Historical Activity Theory is particularly well suited to the study of school libraries and the learning that occurs therein. This paper focuses on the activity theoretic concepts of 'contradictions' and 'expansive learning' as they relate to the development of best practices. Method. Developmental Work Research was applied as a guiding methodology in an intervention study of six high school libraries in Washington State, USA. Library activity is illustrated from multiple perspectives using a triangulated, qualitative approach. Analysis. contradictions and tensions in the general school library activity system are identified, and an intervention was designed to facilitiate the development of expansive instruments. A case example illustrates a second level of analysis and specific points of intervention. Results. analysis reveals that the tensions and contradictions provide opportunities for expansive learning on the part of the teacher-Librarians. The research team can use practitioners' zones of proximal development to guide the alignment of library programme goals and practices. Conclusion. : some limitations and future promise of the framework and its application are discussed. The proposed activity theory toolkit suggest a new way of exploring the practices of teacher-librarians, incorporating research evidence, professional expertise, and reflective decision making.

  13. Combustion chemistry. Activities in the CHEC research programme

    Dam-Johansen, K.; Johnsson, J.E.; Glarborg, P.; Frandsen, F.; Jensen, A.; Oestberg, M. [Technical Univ. of Denmark, Dept. of Chemical Engineering, Lyngby (Denmark)

    1996-12-01

    The combustion chemistry in the oxidation of fossil fuels and biofuels determines together with mixing and heat transfer the required size of a furnace, the emission of gaseous pollutants, and the formation of ash and deposits on surfaces. This paper describes technologies for solid fuels combustion and gives a summary of the fuels, the pollutant chemistry and the inorganic chemistry in combustion processes. Emphasis is put on the work carried out in the CHEC (Combustion and Harmful Emission Control Research Programme). (au) 173 refs.

  14. Adult Workers in Theory or Practice? : Lone Mothers’ Participation in Active Labour Market Programmes in Germany

    Cordula Zabel

    2015-03-01

    Full Text Available This paper examines lone mothers’ participation in active labour market programmes in Germany. Since the 2005 Hartz IV employment and welfare policy reforms, expectations that non-em- ployed parents receiving means-tested benefits should be ready for employment or labour market programme participation have grown stronger. However, discretion for programme assignments is left to individual caseworkers. As a consequence, it is not clear to what extent the formal policy orientation towards an adult worker model of the family is reflected in practical policy implemen- tations. Thus, lone mothers’ participation in active labour market programmes is studied empiri- cally here on the basis of large-scale administrative data, using event-history analysis. Findings are that lone mothers are treated as adult workers with respect to workfare and training pro- grammes even when their children are still quite young. As soon as their youngest child is 3 - 5 years old, lone mothers’ transition rates into these programmes are as high as for childless single women. In the case of programmes that provide more direct pathways into regular employment, like job subsidies and in-firm training programmes, however, participation rates for lone mothers of young children are substantially lower than for childless single women.

  15. Are they working? Market Orientation and the Effectiveness of Active Labour Market Programmes in Ireland

    Philip J O'Connell

    1999-01-01

    This paper presents the first findings of a new study of the labour market impact of a range of active labour market programmes (ALMPs) in Ireland. The paper combines the results of two individual-level data sets to compare the employment outcomes of participants in ALMPs with a comparison group of non-participants over the 1994-1996 period. The analysis focuses on employment probabilities two years post-programme, and shows that programmes with strong linkages to the labour market are more l...

  16. Leptin signaling in Kiss1 neurons arises after pubertal development.

    Roberta M Cravo

    Full Text Available The adipocyte-derived hormone leptin is required for normal pubertal maturation in mice and humans and, therefore, leptin has been recognized as a crucial metabolic cue linking energy stores and the onset of puberty. Several lines of evidence have suggested that leptin acts via kisspeptin expressing neurons of the arcuate nucleus to exert its effects. Using conditional knockout mice, we have previously demonstrated that deletion of leptin receptors (LepR from kisspeptin cells cause no puberty or fertility deficits. However, developmental adaptations and system redundancies may have obscured the physiologic relevance of direct leptin signaling in kisspeptin neurons. To overcome these putative effects, we re-expressed endogenous LepR selectively in kisspeptin cells of mice otherwise null for LepR, using the Cre-loxP system. Kiss1-Cre LepR null mice showed no pubertal development and no improvement of the metabolic phenotype, remaining obese, diabetic and infertile. These mice displayed decreased numbers of neurons expressing Kiss1 gene, similar to prepubertal control mice, and an unexpected lack of re-expression of functional LepR. To further assess the temporal coexpression of Kiss1 and Lepr genes, we generated mice with the human renilla green fluorescent protein (hrGFP driven by Kiss1 regulatory elements and crossed them with mice that express Cre recombinase from the Lepr locus and the R26-tdTomato reporter gene. No coexpression of Kiss1 and LepR was observed in prepubertal mice. Our findings unequivocally demonstrate that kisspeptin neurons are not the direct target of leptin in the onset of puberty. Leptin signaling in kisspeptin neurons arises only after completion of sexual maturation.

  17. Objects prompt authentic scientific activities among learners in a museum programme

    Achiam, Marianne; Simony, Leonora; Kramer Lindow, Bent Erik

    2016-04-01

    Although the scientific disciplines conduct practical work in different ways, all consider practical work as the essential way of connecting objects and phenomena with ideas and the abstract. Accordingly, practical work is regarded as central to science education as well. We investigate a practical, object-based palaeontology programme at a natural history museum to identify how palaeontological objects prompt scientific activity among upper secondary school students. We first construct a theoretical framework based on an analysis of the programme's palaeontological content. From this, we build our reference model, which considers the specimens used in the programme, possible palaeontological interpretations of these specimens, and the conditions inherent in the programme. We use the reference model to analyse the activities of programme participants, and illustrate how these activities are palaeontologically authentic. Finally, we discuss our findings, examining the mechanism by which the specimens prompt scientific activities. We also discuss our discipline-based approach, and how it allows us to positively identify participants' activities as authentic. We conclude by discussing the implications of our findings.

  18. Research programme 'Active Solar Energy Use - Solar Heating and Heat Storage'. Activities and projects 2003

    In this report by the research, development and demonstration (RD+D) programme coordinators the objectives, activities and main results in the area of solar heating and heat storage in Switzerland are presented for 2003. In a stagnating market environment the strategy of the Swiss Federal Office of Energy mainly consists in improving the quality and durability of solar collectors and materials, optimizing combisystems for space heating and domestic hot water preparation, searching for storage systems with a higher energy storage density than in the case of sensible heat storage in water, developing coloured solar collectors for more architectonic freedom, and finalizing a seasonal heat storage project for 100 dwellings to demonstrate the feasibility of solar fractions larger than 50% in apartment houses. Support was granted to the Swiss Testing Facility SPF in Rapperswil as in previous years; SPF was the first European testing institute to perform solar collector labeling according to the new rules of the 'Solar Keymark', introduced in cooperation with the European Committee for Standardization CEN. Several 2003 projects were conducted within the framework of the Solar Heating and Cooling Programme of the International Energy Agency IEA. Computerized simulation tools were improved. With the aim of jointly producing high-temperature heat and electric power a solar installation including a concentrating collector and a thermodynamic machine based on a Rankine cycle is still being developed. Seasonal underground heat storage was studied in detail by means of a validated computer simulation programme. Design guidelines were obtained for such a storage used in the summer time for cooling and in the winter time for space heating via a heat pump: depending on the ratio 'summer cooling / winter heating', cooling requires a cooling machine, or direct cooling without such a machine is possible. The report ends up with the list of all supported RD+D projects

  19. IAEA activities related to research reactor fuel conversion and spent fuel return programmes

    Full text: The IAEA has been involved for more than twenty years in supporting international nuclear non-proliferation efforts associated with reducing the amount of highly enriched uranium (HEU) in international commerce. IAEA projects and activities have directly supported the Reduced Enrichment for Research and Test Reactors (RERTR) programme, as well as directly associated efforts to return research reactor fuel to the country of origin where it was originally enriched. IAEA efforts have included the development and maintenance of several data bases with information related to research reactors and research reactor spent fuel inventories that have been essential in planning and managing both RERTR and spent fuel return programmes. Other IAEA regular budget programmes have supported research reactor fuel conversion from HEU to low enriched uranium, and in addressing issues common to many member states with spent fuel management problems and concerns. The paper briefly describes IAEA involvement since the early 1980's in these areas, including regular budget and Technical Co-operation programme activities, and focuses on efforts in the past five years to continue to support and accelerate U.S. and Russian research reactor spent fuel return programmes. It is hoped that an announcement of the extension of the U.S. Acceptance Programme, which is expected in the very near future, will facilitate the life extensions of many productive TRIGA reactors around the world. (author)

  20. Kissing Bug (Triatoma spp.) Intrusion into Homes: Troublesome Bites and Domiciliation

    Klotz, Stephen A.; F. Mazda Shirazi; Keith Boesen; Beatty, Norman L.; Dorn, Patricia L.; Shannon Smith; Schmidt, Justin O

    2016-01-01

    Kissing bugs (Triatoma spp.) frequently enter homes and bite human and pet occupants. Bites may lead to severe allergic reactions and, in some cases, death. Kissing bugs are also vectors of Trypanosoma cruzi, the cause of Chagas disease. In general, modern houses in the United States are not conducive to domiciliation of kissing bugs (bugs living out their entire life within the home with the presence of eggs, nymphs, adults, and exuviae). Construction features such as concrete foundations, s...

  1. The radiation protection programme activities of the World Health Organization

    The radiation protection activities of the World Health Organization are reviewed. They include studies of radiation protection standards and guidelines, and public health aspects of nuclear power. WHO also provides member states with world data on radioactivity in air, water and food, and assessments of population exposure and health effects. (H.K.)

  2. Baastrup’s disease (kissing spines syndrome): a pictorial review

    Dimitrios K. Filippiadis; Mazioti, Argyro; Argentos, S; Anselmetti, G.; Papakonstantinou, O.; Kelekis, N.; Kelekis, Alexis

    2015-01-01

    Abstract Excessive lordosis is a common finding and may produce mechanical pressure that causes repetitive strains of the interspinous ligament with subsequent degeneration and collapse. Baastrup’s disease (kissing spine syndrome) is a term referring to close approximation of adjacent spinous processes due to degenerative changes of the spine. Baastrup’s disease usually affects the lumbar spine, with L4-L5 being the most commonly affected level. There is higher occurrence at ages over 70 and ...

  3. Application of programme system BRAND for analysis of activation experiments

    Questions related to application of the BRAND program complex, simulating the processes of neutron radiation transfer by Monte Carlo method for analysing the results of measuring the cross sections by activation method, are considered. Results of calculating the corrections to neutron scattering in the air, in the activated sample, which are compared to results by other authors, are presented. The problem of choosing sufficient statistical accuracy of calculation results obtained is considered, choice criterion is proposed and grounded on the base of analysing the calculation results obtained. Questions related to possibilities of applying the complex when planning the forthcoming experiments, analysing experimental results, are discussed and the desired directions in extending the BRAND program complex capabilities are indicated as well. 8 refs.; 4 figs.; 1 tab

  4. What works, who works? The impact of active labour market programmes on the employment prospects of young people in Ireland

    O'Connell, Philip J.; MacGinnity, Fran

    1996-01-01

    The international literature on active labour market programmes has generated inconsistent and confusing, but generally pessimistic, conclusions regarding their impact on the employment prospects of participants. This paper argues that much of this confusion is due to a general lack of attention to qualitative differences between programmes. The paper develops a typology of active labour market programmes, differentiating between training and employment measures on the basis of their orientat...

  5. National programmes and activities on nuclear desalination in India

    Desalination and water reuse has been suggested to augment sources in the coastal areas where water is scarce. The desalination plants are generally located at thermal power stations because steam and electric power are required. The thermal power stations in these areas obtain coal from far distances. Nuclear power coupled to desalination plants is therefore considered to be more useful. The Bhabha Atomic Research Centre has been engaged in R and D work on desalination for the past 15-20 years. The salient details of these activities are discussed

  6. Biennial activity report of metallurgy programme for 1987 and 1988

    The research and development (R and D) activities in the field of metallurgy at Indira Gandhi Centre for Atomic Research, Kalpakkam during 1987-1988 are reported in the form of individual summaries arranged under headings : (1) Mechanical Metallurgy Section, (2) Physical Metallurgy Section, (3) Chemical Metallurgy Section, (4) Materials Technology Section, (5) Division for PIE and NDT Development and (6) Quality Engineering Section. A list of publications by the staff scientists working in the field of metallurgy during report period is given in one of the appendices. (author). figs., tabs

  7. Oncogenic programmes and Notch activity: an 'organized crime'?

    Dominguez, Maria

    2014-04-01

    The inappropriate Notch signalling can influence virtually all aspect of cancer, including tumour-cell growth, survival, apoptosis, angiogenesis, invasion and metastasis, although it does not do this alone. Hence, elucidating the partners of Notch that are active in cancer is now the focus of much intense research activity. The genetic toolkits available, coupled to the small size and short life of the fruit fly Drosophila melanogaster, makes this an inexpensive and effective animal model, suited to large-scale cancer gene discovery studies. The fly eye is not only a non-vital organ but its stereotyped size and disposition also means it is easy to screen for mutations that cause tumours and metastases and provides ample opportunities to test cancer theories and to unravel unanticipated nexus between Notch and other cancer genes, or to discover unforeseen Notch's partners in cancer. These studies suggest that Notch's oncogenic capacity is brought about not simply by increasing signal strength but through partnerships, whereby oncogenes gain more by cooperating than acting individually, as in a ring 'organized crime'. PMID:24780858

  8. Evaluation of physical activity programmes for elderly people - a descriptive study using the EFQM' criteria

    Santos Rute

    2011-02-01

    Full Text Available Abstract Background In the past years, there has been a growing concern in designing physical activity (PA programmes for elderly people, because evidence suggests that such health promotion interventions may reduce the deleterious effects of the ageing process. Quality is an important issue when designing a PA programme for older people. Some studies support the Excellence Model of the European Foundation for Quality Management (EFQM as an operational framework for evaluating the quality of an organization. Within this context, the aim of this study was to characterize the quality management models of the PA programmes developed by Portuguese Local Administration to enhance quality of life for elderly people, according to the criteria of the EFQM Excellence Model. Methods A methodological triangulation was conducted in 26 PA programmes using questionnaire surveys, semi-structured interviews and document analysis. We used standard approaches to the statistical analysis of data including frequencies and percentages for the categorical data. Results Results showed that Processes (65,38%, Leadership (61,03%, Customer results (58,46 and People (51,28% had high percentage occurrences of quality practices. In contrast, Partnerships and resources (45,77%, People results (41,03%, Policy and strategy (37,91%, Key performance results (19,23% and Society results (19,23% had lower percentage occurrences. Conclusions Our findings suggest that although there are some good practices in PA programmes, there are still relevant areas that require improvement.

  9. Quality Control in Mammography: A Pilot Programme for First Level Activity

    Di Maggio, C.; Gambaccini, M.; Gennaro, G.; Indovina, P.L.; Mazzei, F.; Tuffanelli, A

    1998-07-01

    Quality control programmes are the best tools for maintaining optimal performances of mammographic units. Programmes to spread quality control activities have been organised in various countries. This study presents the results of an educational programme having three main objectives: quality assurance promotion, operator training with simple instruments and procedures, and operator training in quality control data analysis. Special kits have been distributed to several mammographic centres. In each centre the kit has been used to execute the following tests: AEC performance, processing conditions, entrance exposure and image quality. The data gathered in 53 centres for a period of 4 weeks are compared and discussed. Several centres were found not to satisfy completely the technical recommendations of the Italian protocol, implying training for radiographers and radiologists in QC procedures is desirable. (author)

  10. It Takes Two to Kiss, but Does it Take Three to Give a Kiss? Categorization Based on Thematic Roles

    Wittenberg, Eva; Snedeker, Jesse

    2013-01-01

    Language is characterised by broad and predictable mappings between meaning and syntactic form. Transitive sentences typically encode two-participant events while ditransitives typically encode three-participant events. Light-verb constructions, however, systematically violate these mappings; for example, some have ditransitive syntax (‘Romeo is giving Juliet a kiss’) but describe what appear to be agent–patient events (Romeo kissing Juliet). We used a conceptual sorting task to explore wheth...

  11. How to implement a balanced programme for musical activities in kindergarten

    Zgonc, Nadja

    2016-01-01

    The preschool and school periods are the most important time for intensive music education. In order to successfully enhance a child’s musical development, nursery teachers should ensure that music activities are equally represented within the programme (singing, playing musical instruments, listening to music, listening to music during creative activities, creating music itself, didactic music games). One of the principles that should be followed by nursery teachers and is set out in the Slo...

  12. Kissing Bug (Triatoma spp.) Intrusion into Homes: Troublesome Bites and Domiciliation.

    Klotz, Stephen A; Shirazi, F Mazda; Boesen, Keith; Beatty, Norman L; Dorn, Patricia L; Smith, Shannon; Schmidt, Justin O

    2016-01-01

    Kissing bugs (Triatoma spp.) frequently enter homes and bite human and pet occupants. Bites may lead to severe allergic reactions and, in some cases, death. Kissing bugs are also vectors of Trypanosoma cruzi, the cause of Chagas disease. In general, modern houses in the United States are not conducive to domiciliation of kissing bugs (bugs living out their entire life within the home with the presence of eggs, nymphs, adults, and exuviae). Construction features such as concrete foundations, solid walls and ceilings, window screens, tight thresholds for doors and windows, and other measures impede bug entry into homes, and air conditioning reduces the need for open doors and windows. Where Chagas disease is endemic in Mexico and Central and South America, homes often have thatch roofs, adobe walls, and open doors and windows. We investigated numerous instances of kissing bug intrusions into homes in Southern Arizona, California, and Louisiana and documented the reactions to kissing bug bites. Our work confirms the importance of modern home construction in limiting kissing bug intrusions. Older homes, especially those lacking modern screening, caulking, and weather stripping to reduce air leakage, may be subject to kissing bug intrusions and domiciliation. We describe a community in Southern Arizona where domiciliation of homes by Triatoma recurva is common. We also provide recent data regarding kissing bug bites and allergic reactions to the bites. PMID:27042091

  13. Process evaluation of a school based physical activity related injury prevention programme using the RE-AIM framework

    van Mechelen Willem

    2010-11-01

    Full Text Available Abstract Background In general, only information regarding the effectiveness of an intervention programme is ever published. However, in recent years evaluating the translatability and feasibility of an intervention programme has become more important. Therefore, this paper presents the results of the evaluation of the iPlay programme aimed at preventing physical activity related injuries in primary school children. Methods The iPlay programme targeted injuries gained through physical activity, and consisted of a teacher's manual, informative newsletters and posters, a website, and set exercises to be carried out during physical education (PE classes. In order to evaluate the iPlay programme for translatability and feasibility, teachers, children and parents who participated in the iPlay programme filled out a questionnaire The objective of this study is to describe the results of the process-evaluation of the iPlay programme based on the five dimensions of the RE-AIM framework. Results The results showed that the participation rate of the children was 100% (reach. Nine percent of the schools who were invited to take part were willing to participate in the study (adoption rate. Teachers stated that they implemented the different elements of the programme partly as intended (implementation. The percentage of children and parents who followed the programme was less than expected. In addition, 52% of the teachers indicated that the current iPlay programme could become standard practice in their teaching routine (maintenance. Conclusion The iPlay programme is a first start in the prevention of physical activity related injuries in children, but further improvements need to be made to the programme on the basis of this process evaluation. Trial registration ISRCTN78846684; http://www.controlled-trials.com

  14. New and recently finalised activities within the NKS Programmes for Nordic cooperation on nuclear reactor safety and emergency preparedness

    Andgren, Karin; Andersson, Kasper Grann; Magnússon, Sigurður M.;

    2015-01-01

    Over the years, NKS has provided funding for hundreds of research activities in fields comprising reactor safety, decommissioning, nuclear and radiological emergency preparedness, and management of radioactive waste. Advanced technologies and methods developed under the NKS framework have been used...... within the Nordic countries as well as internationally. Two programme areas are defined under the NKS platform: The NKS-R programme on nuclear reactor safety and the NKS-B programme on emergency preparedness. Three articles, giving an introduction to NKS and its two programmes, were published in...

  15. Planetary protection R&D activities in the ESA exploration programme

    Kminek, G.

    Since the begin of the Aurora exploration programme in 2001 the Human Spaceflight Microgravity and Exploration Directorate HME of ESA has invested in research and development activities related to planetary protection Some of these activities are focused on the recently approved ExoMars mission others are applicable to Mars missions in general including MSR the technology development of the latter one being part of the exploration core programme The proposed activities have been approved and initiated An overview of the activities and first results will be presented The main activities are begin itemize item Bioburden and Biodiversity evaluation in S C Facilities this activity will cover a period of almost two years and include the standard assay extension of the standard assay culture conditions identification of isolates using 16S rDNA via PCR and test of a rapid spore assay Protocols are developed in coordination with NASA-JPL item Extension of dry heat microbial reduction process to higher temperatures this activity will include a detailed study of the humidity effect on the inactivation kinetics This activity is in coordination with efforts at NASA-JPL item Validation of a dry heat sterilization process item Development of a low-temperature sterilization method the focus of this activity is on vapor hydrogen peroxide item Robotic capabilities for clean AIV AIT item Decontamination of man-rated systems item Definition of functional requirements for a Mars Sample Return Biological Containment Facility end itemize In

  16. Public acceptance activities and tasks in Japan's high-level waste management programme

    In Japan, the current 'Long-Term Programme for Research, Development and Utilisation of Nuclear Energy', that was revised in June 1994, states that the treatment and disposal of high-level radioactive waste remain the most important issues to be resolved in the nuclear power programme of the country. Research and development activities have aimed at establishing geological disposal technologies, with the Power Reactor and Nuclear Fuel Development Corporation (PNC) as a core organisation. By comparison, an implementing organisation for the disposal business is planned to be set up by the year 2000. For this purpose, the Steering Committee on the High-Level Radioactive Waste Project (SHP) was set up in 1993 to initiate full-scale preparation in collaboration with the government and the authorities concerned. The Long-Term Programme provides for enhanced transparency of measures for radioactive waste treatment and disposal for the sake of increasing understanding on the part of the Japanese public. For this and other reasons, it is intended to publish and report widely to the public on the status of R and D and its findings, at appropriate times. The paper discusses the current status of high-level waste disposal in Japan, as well as that of the promotion of public relations activities. The Horonobe-cho and Rokkasho-mura public relations activities are also discussed, as well as the particularity of the disposal business and the requirements for acquiring public understanding, and future challenges in this area. (author)

  17. The Republic of Korea's R and D programme and activities for nuclear desalination

    Since, its introduction in the late 1970s, nuclear energy has been one of the major sources of energy required to support the ambitious and successful economic development and industrialization of the Republic of Korea. Naturally, a strong national desire to achieve self-reliance in nuclear energy technology has developed, and various integrated efforts have been pursued intensively in the domestic nuclear field. The long term national effort has resulted in the firm establishment of associated technologies. These technologies will be further advanced and improved through related R and D programmes and through application to various areas other than electricity generation. Among the various applications of nuclear energy technology, energy supply for sea water desalination has received much favourable attention. Fresh water shortage problems are occurring in certain regions of the country, some of which are expected to become more severe from around the year 2006 unless well planned countermeasures are taken. When combined, the firmly established nuclear energy technology and the desalination technology could be a promising solution to the expected water shortage problems. A feasibility survey on nuclear desalination was carried out, resulting in the establishment of a special R and D programme that started in November 1996. Major efforts are being concentrated on developing a 330 MW(th) co-generation reactor and associated systems to be used for the desalination of sea water for demonstration purposes. An integrated nuclear desalination system will also be developed. The programme will continue for 5 years, until the basic design and development are completed. A summary is given of the status and development programme for nuclear energy technology, the prospects for fresh water demand and supply, the desalination technology established in the Republic of Korea, the specific R and D programme for developing a 330 MW(th) nuclear co-generation reactor, and some

  18. Contaminated land rehabilitation - activities, networks and programmes of the European Union; Altlastenaktivitaeten auf europaeischer Ebene

    Kasamas, H. [CLARINET Koordinierungsstelle, Wien (Austria)

    2000-07-01

    The paper discusses EU programmes and cooperative projects for soil and groundwater rehabilitation, R and D activities for rehabilitation technology development, and the outcome of programmes and projects when available. (orig./CB) [German] Um den Herausforderungen der Altlastenproblematik in den industrialisierten Laendern noch effektiver zu begegnen, wurde die internationale Zusammenarbeit, vor allem auf europaeischer Ebene, verstaerkt in Angriff genommen. Internationale Initiativen zu diversen altlastenrelevanten Problemstellungen sollen eine koordinierte Vorgangsweise zum Nutzen aller teilnehmenden Laender ermoeglichen. Parallele Anstrengungen in der technischen und wissenschaftlichen Entwicklung sollen vermieden und der Einsatz begrenzt vorhandener Mittel effektiviert werden. Der multinationale Erfahrungsaustausch soll die Wiederholung von weniger zielfuehrenden Entwicklungen in anderen Laendern vermeiden helfen. Dieser Beitrag bietet einen Ueberblick ueber Ziele und Ergebnisse diverser internationaler Initiativen im Altlastenbereich und verweist zu weiterfuehrenden Informationsquellen. (orig.)

  19. Evaluation of Activities in Primary Education Programme with The Teachers’ Views (Sample of Sinop Province

    Necdet AYKAÇ

    2007-12-01

    Full Text Available This research, aims to investigate the concept of activity on the basis of learning-teaching duration inaccordance with teachers’ views, teachers guide and class materials in the primary education programme put in to practice in 2005- 2006. The research has two subjects. The first one is the quantitative subject aiming to determine the teachers’ views, the second is theoretical subject aiming to analyze the guide books and class metarials. The quantitative research, aiming to determine the teachers’ ideas is consisted of 184 teachers in total in the center and in the central villages of Sinop. The exemplification in this research is occupied by means of 86 teachers applying the teachers’ views determinating scale. In the research as a tool to collect data, determining teachers’ views scale prepared in 5 likert-type scale with 18 articles has been used. Analyzing with SPSS programme, the data gained from the scale has been stated as frequency and percentage. Theoretical dimension examining teachers’ guide and lesson metarials to put the teachers’ views on a objective base, aims to examine teachers guide books and lesson materials analytically and display the base of teachers’ views. It is stated that most of the teachers present their views in that way: They feel themselves insufficent to applythe activities,the physical opportunities of the schools and the facilities are not enough to apply some activities, the classes are crowded, the activities are not student-centered and active teaching methods are not used in the activities.

  20. RPII Inspection and Licensing Activities and Annual Inspection Programme for 2013

    The objective of this report is to provide an overview of inspection activities of the Radiological Protection Institute of Ireland RPII, to examine the evolution in licensee numbers and to outline the rationale in developing annual inspection programmes. All inspection activities are now carried out within the framework of a quality management system including inspection planning, the training of inspectors, the conduct of inspections as well as post inspection follow up and review. This report also provides an overview of the main features of the quality system

  1. Scientific Goals of the Kunlun Infrared Sky Survey (KISS)

    Burton, Michael; Mould, Jeremy; Cooke, Jeff; Ireland, Michael; Uddin, Syed Ashraf; Zhang, Hui; Yuan, Xiangyan; Lawrence, Jon; Ashley, Michael; Wu, Xuefend; Curtin, Chris; Wang, Lifan

    2016-01-01

    The high Antarctic plateau provides exceptional conditions for conducting infrared observations of the cosmos on account of the cold, dry and stable atmosphere above the ice surface. This paper describes the scientific goals behind the first program to examine the time-varying universe in the infrared from Antarctica - the Kunlun Infrared Sky Survey (KISS). This will employ a small (50 cm aperture) telescope to monitor the southern skies in the 2.4um Kdark window from China's Kunlun station at Dome A, on the summit of the Antarctic plateau, through the uninterrupted 4-month period of winter darkness. An earlier paper discussed optimisation of the Kdark filter for the best sensitivity (Li et al 2016). This paper examines the scientific program for KISS. We calculate the sensitivity of the camera for the extrema of observing conditions that will be encountered. We present the parameters for sample surveys that could then be carried out for a range of cadences and sensitivities. We then discuss several science p...

  2. The Role of Neurotransmitters in Protection against Amyloid-β Toxicity by KiSS-1 Overexpression in SH-SY5Y Neurons

    Chilumuri, Amrutha; Milton, Nathaniel G. N.

    2013-01-01

    Recent studies have suggested that the kisspeptin (KP) and kissorphin (KSO) peptides have neuroprotective actions against the Alzheimer's amyloid- β (A β ) peptide. Overexpression of the human KiSS-1 gene that codes for KP and KSO peptides in SH-SY5Y neurons has also been shown to inhibit A β neurotoxicity. The in vivo actions of KP include activation of neuroendocrine and neurotransmitter systems. The present study used antagonists of KP, neuropeptide FF (NPFF), opioids, oxytocin, estrogen, ...

  3. Objects prompt authentic scientific activities among learners in a museum programme

    Achiam, Marianne; Simony, Leonora; Lindow, Bent Erik Kramer

    2016-01-01

    Although the scientific disciplines conduct practical work in different ways, all consider practical work as the essential way of connecting objects and phenomena with ideas and the abstract. Accordingly, practical work is regarded as central to science education as well. We investigate a practical......, object-based palaeontology programme at a natural history museum to identify how palaeontological objects prompt scientific activity among upper secondary school students. We first construct a theoretical framework based on an analysis of the programme’s palaeontological content. From this, we build our...... palaeontologically authentic. Finally, we discuss our findings, examining the mechanism by which the specimens prompt scientific activities. We also discuss our discipline-based approach, and how it allows us to positively identify participants’ activities as authentic. We conclude by discussing the implications of...

  4. Kissing Mars Rocks with the Rover's RATs: An Educational Exercise to Understand Drilling Rocks on Mars

    Williams, D. A.; Whelley, P. L.; Bleacher, J. E.; Cave, S. R.; Zabala-Aliberto, V. A.; Zabala, A. A.; Greeley, R.

    2007-03-01

    This abstract discusses an E/PO exercise we created for elementary school children that uses Hershey Kisses and straws to simulate the drilling of different rocks on Mars by the MER Rock Abrasion Tool.

  5. The Daughter's Disenchantment: Incest as Pedagogy in Fairy Tales and Kathryn Harrison's the Kiss

    Marshall, Elizabeth

    2004-01-01

    The Kiss, is described as a controversial memoir about father-daughter incest that disturbed the cultural silence in a "well heeled" home. The emotional and psychological terrain of the daughter's experience is discussed.

  6. Activities of the Sofia EC Energy Center in the framework of the THERMIE programme

    The European Community Energy Center in Sofia is responsible for the EC implementation of the THERMIE programme. The programme's activities are promotion and dissemination of existing European technologies leading to better energy management and covering the fields of rational use of hydrocarbons, solid fuels and renewable energy sources. Application of these technologies would lead to substantial energy savings resulting in significant financial and environmental benefits. During its one-year operation the EC Energy Centre has organized and performed specific action as energy audits (food and beverage industrial units and buildings), demonstration projects (local heating control in buildings, diesel engine regulation of buses), training courses and seminars (in energy management and in space heating measuring and regulation), workshops (energy conservation in buildings, the bricks and clays sector and the food and beverage sector) and studies (wind energy potential, 'clean' coal technologies potential). Some of these actions have had very encouraging results showing potential energy savings of the order of 10-20% just by application of simple measures and with small additional investment. The activities of the EC Energy Centre in the coming year aimed at electricity savings along the entire line of electricity generation, transmission and consumption are outlined. (author)

  7. Building Social Capital : A Field Study of the Active, Beautiful and Clean Waters (ABC Waters) Programme in Singapore

    Tovatt, Oliver

    2015-01-01

    This thesis presents a field study examining the effect of the Active, Beautiful and Clean Waters (ABC Waters) Programme in Singapore on social capital. Based on a multi-disciplinary approach and following the theoretical framework of bonding and bridging social capital developed by Robert Putnam and others, three different cases of the ABC Programme were compared, looking particularly at the level of blue-green landscape integration. The three cases comprised the ABC flagship project ‘Bishan...

  8. Short-term results of community-based interventions for improving physical activity: Isfahan Healthy Heart Programme

    Rabiei, Katayoun; Kelishadi, Roya; Sarrafzadegan, Nizal; Sadri, Gholamhossein; Amani, Ahmad

    2010-01-01

    Introduction To assess the effect of a comprehensive community-based programme for increasing physical activity (PA) after 2 years of interventions. Material and methods A 6-year, action-oriented, comprehensive, and integrated community-based study, entitled the Isfahan Healthy Heart Programme, was conducted in Iran from the year 2000. The interventions targeted the whole population of nearly 2,180,000 living in two cities, and were compared with another city considered as a reference. Educat...

  9. Kissing contusion between the posterolateral tibial plateau and lateral femoral condyle: associated ligament and meniscal tears

    Kissing contusion between the posterolateral tibial plateau and lateral femoral condyle is frequently found in association with a tear of the anterior cruciate liagment (ACL). The purpose of this study was to determine which ligamentous and meniscal tears are associated with kissing contusion. We retrospectively reviewed the findings depicted by 323 consecutive MR images of the knee and confirmed at arthroscopy. For the diagnosis of disruption, ligaments, medial menisci (MM) and lateral menisci (LM) were evaluated using accepted criteria. We compared the prevalence and location of meniscal and ligamentous tears between group I (44 knees with kissing contusion) and group II (279 knees without kissing contusion). For statistical analysis the chi-square test was used. ACLs were torn in all 44 knees (100%) with kissing contusion, and 78 (28%) of 279 without kissing contusion. There were ten medial collateral ligament (MCL) tears (23%) in group I, and 17 MCL tears (6%), five lateral collateral ligament (LCL) tears (2%) and ten posterior cruciate ligament (PCL) tears (4%) in group II. In group I, meniscal tears were found in 22 MM (50%) and in 19 LM (43%), while in group II, they occurred in 128 MM (46%) and 128 LM (46%), In group I, 17 (77%) of 22 MM tears and 13 (68%) of 19 LM tears were located in the posterior horn, while in group II, the corresponding figures were 97/128 (76%) and 60 of 128 (47%). The differing prevalence of ACL and MCL tears between the groups was statistically significant (p0.05). Although kissing contusion was a highly specific sign of ACL tears, its presence was also significant among MCL tears. There was no significant difference in meniscal tears with or without kissing contusion

  10. Kissing contusion between the posterolateral tibial plateau and lateral femoral condyle: associated ligament and meniscal tears

    Hong, Hyun Pyo; Lee, Jae Gue; Park, Ji Seon; Ryu, Kyung Nam [Kyunghee Univ., Seoul (Korea, Republic of)

    2004-02-01

    Kissing contusion between the posterolateral tibial plateau and lateral femoral condyle is frequently found in association with a tear of the anterior cruciate liagment (ACL). The purpose of this study was to determine which ligamentous and meniscal tears are associated with kissing contusion. We retrospectively reviewed the findings depicted by 323 consecutive MR images of the knee and confirmed at arthroscopy. For the diagnosis of disruption, ligaments, medial menisci (MM) and lateral menisci (LM) were evaluated using accepted criteria. We compared the prevalence and location of meniscal and ligamentous tears between group I (44 knees with kissing contusion) and group II (279 knees without kissing contusion). For statistical analysis the chi-square test was used. ACLs were torn in all 44 knees (100%) with kissing contusion, and 78 (28%) of 279 without kissing contusion. There were ten medial collateral ligament (MCL) tears (23%) in group I, and 17 MCL tears (6%), five lateral collateral ligament (LCL) tears (2%) and ten posterior cruciate ligament (PCL) tears (4%) in group II. In group I, meniscal tears were found in 22 MM (50%) and in 19 LM (43%), while in group II, they occurred in 128 MM (46%) and 128 LM (46%), In group I, 17 (77%) of 22 MM tears and 13 (68%) of 19 LM tears were located in the posterior horn, while in group II, the corresponding figures were 97/128 (76%) and 60 of 128 (47%). The differing prevalence of ACL and MCL tears between the groups was statistically significant (p<0.05), but differences in the prevalence and location of meniscal tears were not (p>0.05). Although kissing contusion was a highly specific sign of ACL tears, its presence was also significant among MCL tears. There was no significant difference in meniscal tears with or without kissing contusion.

  11. Kissing Bugs in the United States: Risk for Vector-Borne Disease in Humans

    Stephen A. Klotz; Dorn, Patricia L.; Mark Mosbacher; Schmidt, Justin O.

    2014-01-01

    Eleven species of kissing bugs are found in the United States. Their home ranges may be expanding northward, perhaps as a consequence of climate change. At least eight of the species, perhaps all, are reported to harbor Trypanosoma cruzi, the parasite that causes Chagas disease. Because humans are encroaching on kissing bug habitat, there is concern for vector-transmitted Chagas disease in the United States. To date, documented autochthonous cases of Chagas in humans in the United States are ...

  12. Status on the Finnish activities regarding qualification of programmable automation systems

    The research work on qualification of programmable automation system is described which describe the development of methods, tools and practices for the evaluation and licensing of safety critical programmable automation systems. 26 refs

  13. The duplicated longitudinal epiphysis or ''kissing delta phalanx'': evolution and variation in three different disorders

    The delta phalanx, also known as the delta bone, or longitudinal epiphyseal bracket (LEB), has been described in a variety of syndromes and dysplasias. However, the ''kissing delta phalanx'' is not as well recognized in the literature; it consists of a duplicated longitudinal bracketed epiphysis, or a complex of two adjacent delta bones, with opposing convex portions facing each other. Magnetic resonance imaging of the kissing delta phalanx has not been previously described. To describe the evolution, variation and associated osseous anomalies of the kissing delta phalanx in three patients with distinct distal limb malformations using both plain films and magnetic resonance imaging. Patient 1 had Rubinstein-Taybi syndrome and, in addition to a kissing delta phalanx in both feet, had corresponding delta metatarsals (MT1). Patient 2 had Cenani-Lenz syndactyly with distinct variation of the kissing delta phalanx in each hand. He had a disorganized appearance to the phalanges, metacarpal fusions and carpal coalitions. Patient 3 had an isolated oligosyndactyly of the left hand with metacarpal fusions and carpal coalitions. All three patients were followed over time. We describe two types of kissing delta phalanges: separated (without fusion of the corresponding epiphyseal brackets) and nonseparated (with fusion of the corresponding epiphyseal brackets). Both types can be seen in the same patient and are a reflection of the relative degree of segmentation of the two delta bones. (orig.)

  14. A school-based physical activity program to improve health and fitness in children aged 6–13 years ("Kinder-Sportstudie KISS": study design of a randomized controlled trial [ISRCTN15360785

    Knöpfli Martin

    2006-06-01

    Full Text Available Abstract Background Childhood obesity is the result of a long lasting imbalance between energy intake and energy expenditure. A major contributing factor is physical inactivity which is closely linked to bone health, cardiovascular disease risk, fitness and psychological factors. The school seems to provide an excellent setting to enhance levels of physical activity (PA. However, there is insufficient data from previous school-based intervention trials on how to enhance overall PA. It is also unknown whether an intervention aimed at increasing PA is effective in improving the children's health. The purpose of this paper is to outline the design of a school-based randomized, controlled trial (RCT aiming to increase overall PA and to improve fitness and health in 6- to 13-year-old children. Methods/Design 15 schools were randomized to the intervention (n = 9 or the control (n = 6 group, stratified by geographic region (urban vs. rural and by age (1st and 5th grade. Participation was given for all children in the intervention group since in this group the intervention was part of the normal school curriculum. The intervention during one academic year consisted of: 1. two additional physical education classes per week given by trained physical education teachers adding up to a total of five PA classes per week, 2. short PA breaks (2–5 min each during academic lessons, 3. PA home work, and 4. adaptation of recreational areas around the school. All children underwent anthropometric measurements, blood pressure assessment, fitness testing, measurement of PA and they filled out questionnaires. At least 70% of all children agreed to blood sampling and measurements of body composition and bone mineral measurements by dual energy x-ray absorptiometry. The primary endpoints of the study after one year were an increase in total PA by accelerometry, an increase in aerobic fitness measured by the 20 m shuttle run, a decrease in percent body fat derived from

  15. A quality assurance programme for the determination of selenium in foods by instrumental neutron activation analysis

    Selenium is unevenly distributed through the biosphere. The levels, species and bioavailability of selenium in foods depend greatly on the geochemical environment in which they are grown. Variation in geochemical conditions can not only lead to certain diseases in animals but also influence the selenium body burden in humans. For these reasons, there is an increasing interest in monitoring selenium levels in foods and diets. A quality assurance programme has been developed for the determination of low levels of selenium in foods and diets by cyclic and pseudo-cyclic instrumental neutron activation analysis (INAA) using the short-lived (half-life = 17.4 s) 77Sem nuclide. Both conventional and anti-coincidence gamma ray spectrometry techniques have been employed. Pseudo-cyclic INAA in conjunction with anti-coincidence counting has been found to provide the most reliable results. Internal and external quality assessments have been done using a number of parameters. (author)

  16. Overview of EU research activities in transmutation and innovative reactor systems within the Euratom framework programmes

    European Community (EC) (currently 27 Member States) shared-cost research has been organised in Framework Programmes (FP) of durations of 4 - 5 years since 1984. The 6th European Atomic Energy Community (EURATOM) Framework Programme (2002 - 06) and the current 7th FP (2007 - 11) have been allocated a fission research budget respectively of 209 and 287 Million Euro from the EC. There are 10 projects (total budget 70 M Euro, EC contribution 38 M Euro) in all aspects of transmutation ranging from road-mapping exercise to large integrated projects on accelerator driven systems, lead-cooled fast critical systems for waste transmutation, technology, fuel, accelerator facilities for nuclear data etc. In Innovative Reactor concepts, there are about half-a-dozen projects (total budget 30 M Euro, EC contribution 16 M Euro) including High Temperature Reactors, Gas-cooled Fast reactors, road-mapping exercise on sodium fast reactors etc. The main research and training activities in FP7 are: management of radioactive waste, reactor systems, radiation protection, infrastructures, human resources and mobility and training. In the two call for proposals (2007 and 2008) in FP7, 8 projects have been accepted in transmutation and innovative reactor concepts (total budget 53 M Euro, EC contribution 32 M Euro). These research projects cover activities ranging from materials, fuels, treatment of irradiated graphite waste, European sodium fast reactor to the establishment of a Central Design Team of a fast-spectrum transmutation device in Europe. The third call for proposals is underway requesting proposals on nuclear data, thermal hydraulics, gas and lead-cooled fast reactor systems with a total EC budget of 20 M Euro. International collaboration is an important element of the EU research policy. This overview paper will present elements of the strategy of EURATOM research and training in waste management including accelerator driven transmutation systems and Innovative reactor concepts

  17. Ghana's nuclear programme

    The Paper gives the purpose of Ghana's Nuclear Programme and describes some specific research activities and peaceful applications of atomic energy in agriculture, medicine and industry. A discussion of some of the problem facing the programme concludes the Paper. (author)

  18. Kinase Substrate Sensor (KISS), a mammalian in situ protein interaction sensor.

    Lievens, Sam; Gerlo, Sarah; Lemmens, Irma; De Clercq, Dries J H; Risseeuw, Martijn D P; Vanderroost, Nele; De Smet, Anne-Sophie; Ruyssinck, Elien; Chevet, Eric; Van Calenbergh, Serge; Tavernier, Jan

    2014-12-01

    Probably every cellular process is governed by protein-protein interaction (PPIs), which are often highly dynamic in nature being modulated by in- or external stimuli. Here we present KISS, for KInase Substrate Sensor, a mammalian two-hybrid approach designed to map intracellular PPIs and some of the dynamic features they exhibit. Benchmarking experiments indicate that in terms of sensitivity and specificity KISS is on par with other binary protein interaction technologies while being complementary with regard to the subset of PPIs it is able to detect. We used KISS to evaluate interactions between different types of proteins, including transmembrane proteins, expressed at their native subcellular location. In situ analysis of endoplasmic reticulum stress-induced clustering of the endoplasmic reticulum stress sensor ERN1 and ligand-dependent β-arrestin recruitment to GPCRs illustrated the method's potential to study functional PPI modulation in complex cellular processes. Exploring its use as a tool for in cell evaluation of pharmacological interference with PPIs, we showed that reported effects of known GPCR antagonists and PPI inhibitors are properly recapitulated. In a three-hybrid setup, KISS was able to map interactions between small molecules and proteins. Taken together, we established KISS as a sensitive approach for in situ analysis of protein interactions and their modulation in a changing cellular context or in response to pharmacological challenges. PMID:25154561

  19. Ecological patterns of blood-feeding by kissing-bugs (Hemiptera: Reduviidae: Triatominae

    Jorge Eduardo Rabinovich

    2011-06-01

    Full Text Available Host use by vectors is important in understanding the transmission of zoonotic diseases, which can affect humans, wildlife and domestic animals. Here, a synthesis of host exploitation patterns by kissing-bugs, vectors of Chagas disease, is presented. For this synthesis, an extensive literature review restricted to feeding sources analysed by precipitin tests was conducted. Modern tools from community ecology and multivariate statistics were used to determine patterns of segregation in host use. Rather than innate preferences for host species, host use by kissing-bugs is influenced by the habitats they colonise. One of the major limitations of studies on kissing-bug foraging has been the exclusive focus on the dominant vector species. We propose that expanding foraging studies to consider the community of vectors will substantially increase the understanding of Chagas disease transmission ecology. Our results indicate that host accessibility is a major factor that shapes the blood-foraging patterns of kissing-bugs. Therefore, from an applied perspective, measures that are directed at disrupting the contact between humans and kissing-bugs, such as housing improvement, are among the most desirable strategies for Chagas disease control.

  20. A cluster-randomised controlled trial of a physical activity and nutrition programme in retirement villages: a study protocol

    Holt, Anne-Marie; Jancey, Jonine; Lee, Andy H; Kerr, Deborah A; Hills, Andrew P; Anderson, Annie S; Peter A Howat

    2014-01-01

    Introduction Physical activity levels of Australia's ageing population are declining and coincidentally rates of overweight and obesity are increasing. Adequate levels of physical activity and a healthy diet are recognised as important lifestyle factors for the maintenance of a healthy weight and prevention of chronic diseases. Retirement village (RV) residents rarely engage in physical activity and nutrition programmes offered, with poor attendance and low use of existing facilities such as ...

  1. Indian Solar Cities Programme: An Overview of Major Activities and Accomplishments; Preprint

    Kandt, A.

    2012-05-01

    This paper details the Indian Solar City Programme, provides an overview of one city's Master Plan and implementation progress, describes NREL's support of the Indian Solar City Programme, and outlines synergies and differences between the Indian and American programs including unique challenges and opportunities India is facing.

  2. Hydrogen activities in the European Union work-programme; Activites liees a l'hydrogene dans le programme de travail de l'Union Europeenne

    Bahbout, A.; Tartaglia, G.P. [Joint Research Centre, IHCP, Ispra (Italy)

    2000-07-01

    vehicles using hydrogen have joined forces with the aim of improving the coordination of licensing and approval procedures needed for putting hydrogen powered vehicles on the road. The 5. Framework Programme eventually includes hydrogen activities, even if no specific reference is made to hydrogen, following the policy of the Commission to provide directions and fund research according to broad objectives. Hydrogen appears integrated in the wider context of the thematic lines of the work programme. In the programme 'Energy, Environment and Sustainable Development', the activities are concerned with the generation of electricity, and/or heat, with reduced CO{sub 2} emissions from biomass or other fuels. Moreover, development, demonstration, integration of new and renewable energy sources into energy systems is foreseen. Specifically for fuel cells: independent evaluation of their performance against standardised measurement procedures, study of materials involved and possibilities for improvement (abstract only). (authors)

  3. Active optics null test system based on a liquid crystal programmable spatial light modulator

    Ares, Miguel; Royo, Santiago; Sergievskaya, Irina; Riu, Jordi

    2010-11-10

    We present an active null test system adapted to test lenses and wavefronts with complex shapes and strong local deformations. This system provides greater flexibility than conventional static null tests that match only a precisely positioned, individual wavefront. The system is based on a cylindrical Shack-Hartmann wavefront sensor, a commercial liquid crystal programmable phase modulator (PPM), which acts as the active null corrector, enabling the compensation of large strokes with high fidelity in a single iteration, and a spatial filter to remove unmodulated light when steep phase changes are compensated. We have evaluated the PPM's phase response at 635 nm and checked its performance by measuring its capability to generate different amounts of defocus aberration, finding root mean squared errors below {lambda}/18 for spherical wavefronts with peak-to-valley heights of up to 78.7{lambda}, which stands as the limit from which diffractive artifacts created by the PPM have been found to be critical under no spatial filtering. Results of a null test for a complex lens (an ophthalmic customized progressive addition lens) are presented and discussed.

  4. Senior expert group for the review of the Agency's programme of activities. Opening remarks by the Director General

    The document reproduces the opening remarks made by the Director General of the IAEA on 23 March 1998 at the first meeting of the Senior Expert Group for the review of the Agency's programme and activities. The Director General explains his considerations in establishing the group, and the major challenges facing the safe use of nuclear energy and technologies

  5. Programme wood/energy 2000-2006. Activity Report for 2000-2004

    When ADEME launched its Wood fuel programme throughout all of France in late 1999, its aim was to guide this resource supply chain to maturity and stable development in all user sectors: domestic, multi-family housing, commercial/institutional and industrial applications. To this end the Wood fuel Programme 2000-2006 was assigned objectives and endowed with significant financial means for studies and coordination in order to support and carry out general-interest projects, piloted by ADEME. The stated goal was to replace fossil fuels, avoid carbon emissions and establish quality assurance standards for household firewood and wood-fired devices. This report makes a status of ADEME's Wood fuel programme for the 2000-2004 era: - Domestic heating: After a drop during the 1990's, figures since 1999 of sales of wood-fuel domestic heating equipment (closed heaters, glass-door fires and stoves) have shown a significant rise. On average over 30 years, wood consumption has risen to 7.2 million TOE (40 million cubic metres) per year; - Industry: It is thought there are 1000 wood-fired heaters (above 1 megawatt) used in French industry. These are found mainly in timber-based industries and in timber crushing plants. This amounts to a total power output of 2.5 gigawatts. In the primary and secondary wood processing industries, the increase in the number of wood-fired boilers and energy produced has reached 5% per year Results of a call for carbon energy projects (APEC) was 61 submitted of which 52 were selected; 9 projects pending (166.5 K of aid from ADEME); and 35 projects begun (1,649 K of aid from ADEME). - Local authority and service sector wood-fired heating systems: At the end of 2004, the number of local authority active boilers was 641, producing 430 megawatts. This is an increase of an average of 13% year on year since 2000. By the end of 2004, the target had already been met for the number of boilers being financed (1,090). By 2006 however we still need to generate a

  6. JRC/IE support activities to PHARE nuclear safety programmes. Dissemination of PHARE project results

    Nuclear safety in Europe is one of European Union's primary concerns, therefore the European Union decided to take a prominent role to help the New Independent States and countries of Central and Eastern Europe to ensure the safety of their nuclear reactors. The European Union TACIS and PHARE programmes in nuclear safety have been undertaken since 1990. The European Commission's Directorate General External Relations (EC DG RELEX) and, Directorate General Europe Aid Co-operation Office (EC DG AIDCO), are responsible for programming and management of implementation of TACIS projects. Directorate General Enlargement (EC DG ELARG) is responsible for programming PHARE programmes, but implementation of most projects has been decentralised since 1999 budget year to the Beneficiary countries. DG ELARG acts as backstopping for the relevant EC Delegations. In these activities, the TSSTP Unit at the JRC/IE in Petten, The Netherlands, is a technical and scientific adviser of DG RELEX and DG AIDCO and provides support to DG ELARG for very specific technical issues. Several PHARE projects aiming at improving nuclear safety have been successfully implemented for a number of plants from Central and Eastern Europe. In some cases major safety issues have been addressed by means of multi-country projects and results have been disseminated to the rest of the nuclear community. Although a lot of information has been exchanged at a bilateral level, further effort is needed to collect the project results in a systematic way and make them available by means of the internet. At present the TSSTP Unit is implementing two projects for dissemination of PHARE project results. This activity will take a better advantage of today's communication technologies and ensure the management of the acquired knowledge through preservation and user-friendly access and retrieval of the project results. The paper provides an outline of the TSSTP Unit relevant knowledge preservation initiative, a description

  7. Differential regulation of kiss1 expression by melatonin and gonadal hormones in male and female Syrian hamsters

    Ansel, L; Bolborea, M; Bentsen, A H;

    2010-01-01

    rodents, Kiss1 is expressed in the anteroventral periventricular nucleus (AVPV) and in the arcuate nucleus (ARC). Because both the duration of the nocturnal peak of melatonin and circulating sex steroid levels vary with photoperiod, the aim of this study was to determine whether melatonin and sex steroids...... as compared to LD animals, 2) sex steroid treatment in SD-adapted male and female hamsters increased the number of Kiss1 neurons in the AVPV but decreased it in the ARC, 3) melatonin administration to LD-adapted hamsters decreased Kiss1 mRNA level in both the AVPV and the ARC in intact animals...... Syrian hamster hypothalamus is down-regulated in SD via different mechanisms. In the ARC, melatonin inhibits Kiss1 via a direct effect on the hypothalamus, and this effect is probably sex steroid dependent, whereas in the AVPV, the decrease in Kiss1 expression appears to be secondary to the melatonin...

  8. Expression of Kisspeptins and Kiss Receptors Suggests a Large Range of Functions for Kisspeptin Systems in the Brain of the European Sea Bass

    Escobar, Sebastián; Servili, Arianna; Espigares, Felipe; Gueguen, Marie-Madeleine; Brocal, Isabel; Felip, Alicia; Gómez, Ana; Carrillo, Manuel; Zanuy, Silvia; Kah, Olivier

    2013-01-01

    This study, conducted in the brain of a perciform fish, the European sea bass, aimed at raising antibodies against the precursor of the kisspeptins in order to map the kiss systems and to correlate the expression of kisspeptins, kiss1 and kiss2, with that of kisspeptin receptors (kiss-R1 and kiss-R2). Specific antibodies could be raised against the preprokiss2, but not the preoprokiss1. The data indicate that kiss2 neurons are mainly located in the hypothalamus and project widely to the subpallium and pallium, the preoptic region, the thalamus, the pretectal area, the optic tectum, the torus semicircularis, the mediobasal medial and caudal hypothalamus, and the neurohypophysis. These results were compared to the expression of kiss-R1 and kiss-R2 messengers, indicating a very good correlation between the wide distribution of Kiss2-positive fibers and that of kiss-R2 expressing cells. The expression of kiss-R1 messengers was more limited to the habenula, the ventral telencephalon and the proximal pars distalis of the pituitary. Attempts to characterize the phenotype of the numerous cells expressing kiss-R2 showed that neurons expressing tyrosine hydroxylase, neuropeptide Y and neuronal nitric oxide synthase are targets for kisspeptins, while GnRH1 neurons did not appear to express kiss-R1 or kiss-R2 messengers. In addition, a striking result was that all somatostatin-positive neurons expressed-kissR2. These data show that kisspeptins are likely to regulate a wide range of neuronal systems in the brain of teleosts. PMID:23894610

  9. An Analysis of Theme in Crista Faust’s Novel Supernatural: Coyote's Kiss

    Viryanza, Ryan Rosta

    2015-01-01

    Literature is the art of written work. And the novel is one of the literary work and the three important branches of literature: novel, poetry, and drama. Novel contains an interesting story and moral message for the readers. The paper entitled “An Analysis of Theme in Christa Faust’s Novel Supernatural: Coyote's Kiss is about the theme elements in a literary work consist of main-theme, sub-theme, and the analogy of the novel to real life. Supernatural: Coyote's kiss is a novel by Christa Fau...

  10. Labour market programmes and labour market outcomes: a study of the Swedish active labour market interventions

    Adda, Jérôme; Costa Dias, Mónica; Meghir, Costas; Sianesi, Barbara

    2007-01-01

    This paper assesses the impact of Swedish welfare-to-work programmes on labour market performance including wages, labour market status, unemployment duration and future welfare-to-work participation. We develop a structural dynamic model of labour supply which incorporates detailed institutional features of these policies and allows for selection on observables and unobservables. We estimate the model from a rich administrative panel data set and show that training programmes - which account...

  11. Activating welfare recipients with health complaints: Reasons for failure of a cognitive training programme

    Inge Bramsen

    2011-03-01

    Full Text Available Activating welfare recipients with health complaints: Reasons for failure of a cognitive training programme In western welfare states, a trend towards activation has led to the development of interventions aimed at welfare recipients with health complaints. Forms of coercion are increasingly applied within this activation policy. An example of this approach is the Dutch project Healthy to Work (HtW which developed and evaluated an intervention combining an exercise program with cognitive training. Although HtW had been selected as an example of good practice, a randomized clinical trial did not show beneficial effects. This cognitive training programme based on rational-emotive therapy has not been studied separately as yet. Therefore, an in-depth qualitative study was conducted to examine reasons for failure. A purposive sample of six trainers were interviewed. The results indicated that trainers encountered problems with the heterogeneity of participants and different problems, expectations and labour market obstructions than expected beforehand. The mandatory nature of HtW had a negative effect on motivation of both participants and trainers. The discussion questions the assumption that coping style and cognitions of welfare recipients with health problems are the main obstacles to finding work, and the policy to ignore physical limitations of participants. We suggest that in this complex area of practice, improvement can be achieved by allowing trainers to adapt and learn during the process, while also reflecting on normative aspects, and by taking perspectives of welfare recipients themselves into account. Het activeren van uitkeringsgerechtigden met gezondheidsklachten: Oorzaken voor het falen van een cognitief trainingsprogramma Een groeiende nadruk op de activering van uitkeringsgerechtigden heeft in veel Westerse verzorgingsstaten geleid tot de ontwikkeling van interventies die gericht zijn op uitkeringsgerechtigden met

  12. Technology Programme

    The technology activities carried out by the Euratom-ENEA Association in the framework of the European Fusion Development Agreement concern the Next Step (International Thermonuclear Experimental Reactor - ITER), the Long-Term Programme (breeder blanket, materials, International Fusion Materials Irradiation Facility - IFMIF), Power Plant Conceptual Studies and Socio-Economic Studies. The Underlying Technology Programme was set up to complement the fusion activities as well to develop technologies with a wider range of interest. The Technology Programme mainly involves staff from the Frascati laboratories of the Fusion Technical and Scientific Unit and from the Brasimone laboratories of the Advanced Physics Technologies Unit. Other ENEA units also provide valuable contributions to the programme. ENEA is heavily engaged in component development/testing and in design and safety activities for the European Fusion Technology Programme. Although the work documented in the following covers a large range of topics that differ considerably because they concern the development of extremely complex systems, the high level of integration and coordination ensures the capability to cover the fusion system as a whole. In 2004 the most significant testing activities concerned the ITER primary beryllium-coated first wall. In the field of high-heat-flux components, an important achievement was the qualification of the process for depositing a copper liner on carbon fibre composite (CFC) hollow tiles. This new process, pre-brazed casting (PBC), allows the hot radial pressing (HRP) joining procedure to be used also for CFC-based armour monoblock divertor components. The PBC and HRP processes are candidates for the construction of the ITER divertor. In the materials field an important milestone was the commissioning of a new facility for chemical vapour infiltration/deposition, used for optimising silicon carbide composite (SiCf/SiC) components. Eight patents were deposited during 2004

  13. Technology Programme

    Batistoni, Paola; De Marco, Francesco; Pieroni, Leonardo (ed.)

    2005-07-01

    The technology activities carried out by the Euratom-ENEA Association in the framework of the European Fusion Development Agreement concern the Next Step (International Thermonuclear Experimental Reactor - ITER), the Long-Term Programme (breeder blanket, materials, International Fusion Materials Irradiation Facility - IFMIF), Power Plant Conceptual Studies and Socio-Economic Studies. The Underlying Technology Programme was set up to complement the fusion activities as well to develop technologies with a wider range of interest. The Technology Programme mainly involves staff from the Frascati laboratories of the Fusion Technical and Scientific Unit and from the Brasimone laboratories of the Advanced Physics Technologies Unit. Other ENEA units also provide valuable contributions to the programme. ENEA is heavily engaged in component development/testing and in design and safety activities for the European Fusion Technology Programme. Although the work documented in the following covers a large range of topics that differ considerably because they concern the development of extremely complex systems, the high level of integration and coordination ensures the capability to cover the fusion system as a whole. In 2004 the most significant testing activities concerned the ITER primary beryllium-coated first wall. In the field of high-heat-flux components, an important achievement was the qualification of the process for depositing a copper liner on carbon fibre composite (CFC) hollow tiles. This new process, pre-brazed casting (PBC), allows the hot radial pressing (HRP) joining procedure to be used also for CFC-based armour monoblock divertor components. The PBC and HRP processes are candidates for the construction of the ITER divertor. In the materials field an important milestone was the commissioning of a new facility for chemical vapour infiltration/deposition, used for optimising silicon carbide composite (SiCf/SiC) components. Eight patents were deposited during 2004

  14. Fusion reactor technology studies common development activities of CEA and KFK in the frame of the european community fusion programme

    In 1982, it was decided in the European Community to complement the fusion programme by a technology part. The initial content of this technology programme was defined by European experts. The laboratories associated to Euratom were invited to participate with proposals, which were then selected by the Fusion Technology Steering Committee. Coherent with these activities, steps were taken to define the next generation of fusion experiments by the newly founded Next European Torus (NET) Team. To contribute in the most efficient way, CEA and KfK have agreed to cooperate by complementary activities, common experiments and by forming common research groups. The particular agreements have been kept open for partners from other EC laboratories to join. The different cooperative activities in the field of nuclear technologies are described below together with first results and findings

  15. National Report Germany: Sounding Rocket and Balloon Research Activities Supported by the German Space Programme in 2013-2015

    Kuhl, R.; Gritzner, C.; Friedrichs, D.

    2015-09-01

    Mainly sounding rockets but also stratospheric balloons have played a crucial role in implementing the German Space Programme since many years. Research activities were conducted in the fields of Microgravity Research, Space Science, Earth Observation, Space Technology Development, and Education. Currently, the mesosphere and ionosphere of the Earth and the photosphere and chromosphere of the Sun are in the focus of German research activities in the field of Space Science. Microgravity related topics are studied in the disciplines of Life and Physical Sciences during ballistic TEXUS and MAPHEUS rocket flights. A lot of student activities are currently supported by the agencies SNSB and DLR under the auspices of the Swedish-German programme REXUS/BEXUS.

  16. The Impact of Adventure Based Activity at Malaysian National Service Training Programme on Team Cohesion: A Demographic Analysis.

    Jaffry Zakaria

    2012-12-01

    Full Text Available The present study examines the effects of physical module elements (adventure based activity included in the Malaysian National Service Programme and to investigate the socio-demographic variables impact on team cohesion building among the participants. In this study, the participants were selected from three different camps, namely, Tasoh camp, Guar Chenderai camp and Meranti camp, located in the state of Perlis, Malaysia. The participants were those from the second batch intake in the year 2007. The sample sizes comprised of 994 participants (480=males, 514=females. The present study applied a pre-test and post-test design. The group was tested before and after the programme. This design was chosen because it could measure the impacts of the adventure-based activity towards team cohesion over time through the pre- and post-test scores (Berg & Latin, 2004. The variables comprised of the demographic factors (age, gender and place of residence, which included team cohesion were measured by Group Environmental Questionnaire (GEQ (Carron, Widmeyer, & Brawley, 1985. Results indicated that the participants of the National Service Training Programme underwent group cohesion change during the Physical Module activities (adventure based activities that were carried out at the camp. The changes were observable based on the statistically analyzed data during the pre and post-test.

  17. Metastasis suppressor KISS1 seems to reverse the Warburg effect by enhancing mitochondrial biogenesis

    Cancer cells tend to utilize aerobic glycolysis even under normoxic conditions, commonly called the "Warburg Effect." Aerobic glycolysis often directly correlates with malignancy, but its purpose, if any, in metastasis remains unclear. When wild-type KISS1 metastasis suppressor is expressed, aerob...

  18. The Impact of Adventure Based Activity at Malaysian National Service Training Programme on Team Cohesion: A Demographic Analysis.

    Jaffry Zakaria; Mazuki Mohd Yasim; Md Amin Md Taff

    2012-01-01

    The present study examines the effects of physical module elements (adventure based activity) included in the Malaysian National Service Programme and to investigate the socio-demographic variables impact on team cohesion building among the participants. In this study, the participants were selected from three different camps, namely, Tasoh camp, Guar Chenderai camp and Meranti camp, located in the state of Perlis, Malaysia. The participants were those from the second batch intake in the yea...

  19. Do welfare-to-work initiatives work? : evidence from an activation programme targeted at social security recipients in Norway

    Rønsen, Marit; Skarðhamar, Torbjørn

    2007-01-01

    Abstract: This paper presents results from an evaluation of a Norwegian initiative to combat poverty launched in 2003. Central to the plan is a broad spectrum of rehabilitation and activation measures intended to help long-term social security recipients from welfare to work. We illuminate short-term effects up to the end of 2004, taking a dual approach: First, we analyse transitions to work among participants in the programme and study the determinants of this process by means of survival...

  20. Longitudinal changes in heart rate after participating in the Groningen Active Living Model (GALM) recreational sports programme

    Jong, Johan de; Lemmink, Koen; Scherder, Erik; Stewart, Roy; King, Abby

    2009-01-01

    The aim of this study was to investigate changes in heart rate during submaximal exercise as an index of cardiovascular function in older adults participating in the Groningen Active Living Model recreational sports programme who were sedentary or underactive at baseline. A repeated measurement design was conducted; 151 participants were included, providing 398 heart rate files over a period of 18 months. Multi-level analyses were conducted; growth and final models were developed. Significant...

  1. Decrease in heart rate after longitudinal participation in the Groningen Active Living Model (GALM) recreational sports programme

    Jong, Johan de; Lemmink, Koen; Scherder, Erik; Stewart, Roy; King, Abby; Stevens, Martin

    2009-01-01

    The aim of this study was to investigate changes in heart rate during submaximal exercise as an index of cardiovascular function in older adults participating in the Groningen Active Living Model recreational sports programme who were sedentary or underactive at baseline. A repeated measurement design was conducted; 151 participants were included, providing 398 heart rate files over a period of 18 months. Multi-level analyses were conducted; growth and final models were developed. Significant...

  2. Active surveillance and control programme for Salmonella Dublin in Cattle

    Nielsen, Liza Rosenbaum; Rattenborg, Erik

    2011-01-01

    surveillance systems. Register data might be useful for design of effective surveillance programmes for Salmonella Dublin in cattle in the future. Statistical analysis of register-based variables confirmed previously known risk factors for becoming test-positive (i.e. purchase of animals from test...

  3. Benefits from joint research activities by universities and national institutions for nuclear programmes in a developing country

    In a developing country such as Greece where a nuclear power programme is under consideration and faces special problems, collaboration between universities and national institutions in joint research projects, besides helping to obtain valuable results, is the best way to benefit both parties in their individual programmes. Ten years ago a joint research programme between the Control Group of the University of Patras and subsequently the National Technical University of Athens (NTUA) on the one side, and the Group of Research Reactor Modelling, Reliability and Failure Detection of the Nuclear Technology Department of the NRCPS 'Democritos' on the other, was established. The co-operation proved to be fruitful as regards (a) exchanging information and know-how relating to academically oriented activities and nuclear reactor and laboratory experiments and research; (b) working in joint research programmes on systems control theory and applications to nuclear reactors; and (c) training of post-graduate students in theory and applications as well as in methods and techniques used in a nuclear laboratory. Particular areas of joint activity and research are nuclear reactor modelling, simulation and identification; control theory methodology as applied to nuclear reactors; treatment of nuclear power systems using large scale systems techniques; microprocessor-based systems for nuclear reactor measurements, data acquisition and nuclear signal processing and control; analysis and optimization of system reliability and maintenance with application to nuclear reactor systems; dynamic failure detection of nuclear systems using state observers and filters; and application of knowledge-based systems and artificial intelligence techniques to nuclear reactor systems (evaluation, operation, maintenance and safety procedures). Naturally, this co-operation has contributed to the preparation of the necessary manpower for carrying out research and practical work in the systems and

  4. The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent

    Sutcliffe Margaret

    2011-04-01

    Full Text Available Abstract Background Humans and mice with loss of function mutations in GPR54 (KISS1R or kisspeptin do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in the hypothalamus have yet to be explored by genome-wide methods. Results We show here, using 1 million exon mouse arrays (Exon 1.0 Affymetrix and quantitative polymerase chain reaction (QPCR validation to analyse microdissected hypothalamic tissue from Gpr54 and Kiss1 knockout mice, the extent of transcriptional regulation in the hypothalamus. The sensitivity to detect important transcript differences in microdissected RNA was confirmed by the observation of counter-regulation of Kiss1 expression in Gpr54 knockouts and confirmed by immunohistochemistry (IHC. Since Gpr54 and Kiss1 knockout animals are effectively pre-pubertal with low testosterone (T levels, we also determined which of the validated transcripts were T-responsive and which varied according to genotype alone. We observed four types of transcriptional regulation (i genotype only dependent regulation, (ii T only dependent regulation, (iii genotype and T-dependent regulation with interaction between these variables, (iv genotype and T-dependent regulation with no interaction between these variables. The results implicate for the first time several transcription factors (e.g. Npas4, Esr2, proteases (Klk1b22, and the orphan 10-transmembrane transporter TMEM144 in the biology of GPR54/kisspeptin function in the hypothalamus. We show for the neuronal activity regulated transcription factor NPAS4, that distinct protein over-expression is seen in the hypothalamus and hippocampus in Gpr54 knockout mice. This links for the first time the hypothalamic-gonadal axis with this important regulator of inhibitory synapse formation. Similarly we confirm TMEM144 up-regulation in the hypothalamus by RNA in situ hybridization and western blot. Conclusions Taken together, global

  5. Mutations of the kissing-loop dimerization sequence influence the site specificity of murine leukemia virus recombination in vivo

    Mikkelsen, J G; Lund, Anders Henrik; Duch, M; Pedersen, F S

    2000-01-01

    -cycle transfer of Akv murine leukemia virus-based vectors harboring defective primer binding site sequences, we now report that modifications of the kissing-loop structure, ranging from a deletion of the entire sequence to introduction of a single point mutation in the loop motif, significantly disturb site...... synthesis in newly infected cells. We have previously shown that template shifts within the 5' leader of murine leukemia viruses occur preferentially within the kissing stem-loop motif, a cis element crucial for in vitro RNA dimer formation. By use of a forced recombination approach based on single...... specificity of recombination within the highly structured 5' leader region. In addition, we find that an intact kissing-loop sequence favors optimal RNA encapsidation and vector transduction. Our data are consistent with the kissing-loop dimerization model and suggest that a direct intermolecular RNA...

  6. Protocol of a longitudinal cohort study on physical activity behaviour in physically disabled patients participating in a rehabilitation counselling programme: ReSpAct

    Alingh, Rolinde A; Hoekstra, Femke; van der Schans, Cees P; Hettinga, Florentina J; Dekker, Rienk; van der Woude, Lucas H V

    2015-01-01

    Introduction Stimulating physical activity behaviour in persons with a physical disability is important, especially after discharge from rehabilitation. A tailored counselling programme covering both the period of the rehabilitation treatment and the first months at home seems on the average effective. However, a considerable variation in response is observed in the sense that some patients show a relevant beneficial response while others show no or only a small response on physical activity behaviour. The Rehabilitation, Sports and Active lifestyle (ReSpAct) study aims to estimate the associations of patient and programme characteristics with patients’ physical activity behaviour after their participation in a tailored counselling programme. Methods and analysis A questionnaire-based nationwide longitudinal prospective cohort study is conducted. Participants are recruited from 18 rehabilitation centres and hospitals in The Netherlands. 2000 participants with a physical disability or chronic disease will be followed during and after their participation in a tailored counselling programme. Programme outcomes on physical activity behaviour and patient as well as programme characteristics that may be associated with differences in physical activity behaviour after programme completion are being assessed. Data collection takes place at baseline and 14, 33 and 52 weeks after discharge from rehabilitation. Ethics and dissemination The study protocol has been approved by the Medical Ethics Committee of the University Medical Centre Groningen and at individual participating institutions. All participants give written informed consent. The study results will provide new insights into factors that may help explain the differences in physical activity behaviour of patients with a physical disability after they have participated in the same physical activity and sports stimulation programme. Thereby, it will support healthcare professionals to tailor their guidance and

  7. REVIEW OF THE NATIONAL RESTOCKING PROGRAMMEACTIVE PROTECTION OF NATIVE CRAYFISH IN POLAND” 1999-2001

    ŠMIETANA P.

    2004-01-01

    Full Text Available After the first spread of crayfish plague (aphanomycosis at the end of the nineteenth century, the formerly abundant populations of native crayfish in Poland declined drastically. Analysis of historical data on the occurrence and distribution of crayfish in Poland led to the conclusion that without human intervention the native crayfish species would be at high risk of being made extinct. The largest programme concerning crayfish monitoring and restocking in Poland was “Active protection of native crayfish in Poland” conducted by the Inland Fisheries Institute, the Department of Ecology, University of Szczecin, the Department of Zoology, Warsaw Agricultural University and the University of Warmia and Mazury that was funded by the EkoFundusz Foundation and Inland Fisheries Institute in 1999-2001. One of the main objectives and results of this programme was the determination of indigenous crayfish distribution in Poland (mainly Astacus astacus and Astacus leptodactylus and the restocking of suitable habitats with indigenous crayfish. The densest populations (> 2 500 adult individuals per hectare were used as a source of restocking material. Restocking was performed in 54 water bodies using a total of 45 200 individuals of A. astacus and 9 800 of A. leptodactylus. Between 2001-2002, the success of the restocking programme was monitored. According to the results obtained so far, the restocking exercise has been successful in at least 60.8% of the cases.

  8. [Analysis of fourteen French national programmes on physical activity and sports as determinants of health from 2001 to 2006].

    Bréchat, Pierre-Henri; Vogel, Thomas; Berthel, Marc; Kaltenbach, Georges; Le Divenah, Aude; Segouin, Christophe; Rymer, Roland; Lonsdorfer, Jean

    2009-01-01

    Physical activity and sports are considered as one of the determinants of health. The aim of this study is to review the rationale for the formulation of this public health issue and its integration in national action plans. The study shows that fourteen national programmes were drafted and implemented between 2001 and 2006 by seven institutions. The research methodology was based on crossing data obtained from semi-directed interviews and documents regarding the design, implementation and follow-up of these programmes. For the conditions of the success, the fourteen actions scored an average of 175.0 +/- 66.9 out of 300%. Public health actors and professionals must be given more opportunities to involve themselves and engage in developing stronger relationships and linkages, in particular with the institutional and community settings. In general, the most invested parts of a programme are the structural and operational aspects of activities. Six significant points surfaced from the study: consideration of drug use as an addictive behaviour; recognition of the psychological stress of professional athletes; acknowledgment of youth as being at high risk for doping behaviour; integration of the concept that physical activity and sports must take the benefit/risk perspective into account; and the necessity to promote health. Through the exchange of numerous local and regional experiences, an optimisation of their synergistic connections was made possible on a continuum extending from "health promotion through physical activity and sports" to "prevention of drug-use and doping behaviours". Professionals have been able to develop actions in the above-mentioned domains across this continuum that have, to date, remained isolated. Proposals are made to strengthen these dynamics. Other health determinants and public health priorities could be investigated with the same methodology. PMID:19425524

  9. A combinatorial approach to the repertoire of RNA kissing motifs; towards multiplex detection by switching hairpin aptamers.

    Durand, Guillaume; Dausse, Eric; Goux, Emma; Fiore, Emmanuelle; Peyrin, Eric; Ravelet, Corinne; Toulmé, Jean-Jacques

    2016-05-19

    Loop-loop (also known as kissing) interactions between RNA hairpins are involved in several mechanisms in both prokaryotes and eukaryotes such as the regulation of the plasmid copy number or the dimerization of retroviral genomes. The stability of kissing complexes relies on loop parameters (base composition, sequence and size) and base combination at the loop-loop helix - stem junctions. In order to identify kissing partners that could be used as regulatory elements or building blocks of RNA scaffolds, we analysed a pool of 5.2 × 10(6) RNA hairpins with randomized loops. We identified more than 50 pairs of kissing RNA hairpins. Two kissing motifs, 5'CCNY and 5'RYRY, generate highly stable complexes with KDs in the low nanomolar range. Such motifs were introduced in the apical loop of hairpin aptamers that switch between unfolded and folded state upon binding to their cognate target molecule, hence their name aptaswitch. The aptaswitch-ligand complex is specifically recognized by a second RNA hairpin named aptakiss through loop-loop interaction. Taking advantage of our kissing motif repertoire we engineered aptaswitch-aptakiss modules for purine derivatives, namely adenosine, GTP and theophylline and demonstrated that these molecules can be specifically and simultaneously detected by surface plasmon resonance or by fluorescence anisotropy. PMID:27067541

  10. Field programmable gate array based data digitisation with commercial elements

    One of the most important aspects of particle identification experiments is the digitisation of time, amplitude and charge data from detectors. These conversions are mostly undertaken with Application Specific Integrated Circuits (ASICs). However, recent developments in Field Programmable Gate Array (FPGA) technology allow us to use commercial electronic components for the required Front-End Electronics (FEE) and to do the digitisation in the FPGA. It is possible to do Time-of-Flight (ToF), Time-over-Threshold (ToT), amplitude and charge measurements with converters implemented in FPGA. We call this principle come and kiss: use COmplex ComMErcial Elements and Keep It Small and Simple.

  11. Field programmable gate array based data digitisation with commercial elements

    One of the most important aspects of particle identification experiments is the digitisation of time, amplitude and charge data from detectors. These conversions are done mostly with Application Specific ICs (ASICs). However, the recent developments in Field Programmable Gate Array (FPGA) technology allow us to use commercial electronic components for the required Front-End Electronics (FEE) and do the digitisation in the FPGA. It is possible to do Time-of-Flight (ToF), Time-over-Threshold (ToT), amplitude and charge measurements with converters implemented in FPGA. We call this principle COME and KISS: Use COMplex COMmercial Elements and Keep It Small and Simple.

  12. Programme development for the controlled removal of contamination and activated materials during the decommissioning of nuclear facilities

    Over the past decade Taywood Engineering Limited has been carrying out a development programme on the use of explosives for the controlled removal of activated and/or contaminated parts of nuclear facilities undergoing decommissioning. Factors likely to affect the concrete removal have been investigated including concrete removal from re-entrant corners, curved surfaces and ducts, and from behind reinforcement and steel liners. Procedures for achieving a required level of material removal without impairing the remaining structure had been developed. The application of finite element methods to this class of problem with emphasis on numerical modelling of the concrete material has been investigated. (author)

  13. Percutaneous reconstruction of the innominate bifurcation using the retrograde 'kissing stents' technique

    Nagata, Shun-ichi; Kazekawa, Kiyoshi; Matsubara, Shuko [Fukuoka University Chikushi Hospital, Department of Neurosurgery, Chikushino, Fukuoka (Japan); Sugata, Sei [Bironoki Neurosurgical Hospital, Shibushi, Kagoshima (Japan)

    2006-08-15

    Obstructions of the supraaortic vessels are an important cause of morbidity associated with a variety of symptoms. Percutaneous transluminal angioplasty has evolved as an effective and safe treatment modality for occlusive lesions of the supraaortic vessels. However, the endovascular management of an innominate bifurcation has not previously been reported. A 53-year-old female with a history of systematic hypertension, diabetes mellitus and hypercholesterolemia presented with left hemiparesis and dysarthria. Angiography of the innominate artery showed a stenosis of the innominate bifurcation. The lesion was successfully treated using the retrograde kissing stent technique via a brachial approach and an exposed direct carotid approach. The retrograde kissing stent technique for the treatment of a stenosis of the innominate bifurcation was found to be a safe and effective alternative to conventional surgery. (orig.)

  14. Percutaneous reconstruction of the innominate bifurcation using the retrograde 'kissing stents' technique

    Obstructions of the supraaortic vessels are an important cause of morbidity associated with a variety of symptoms. Percutaneous transluminal angioplasty has evolved as an effective and safe treatment modality for occlusive lesions of the supraaortic vessels. However, the endovascular management of an innominate bifurcation has not previously been reported. A 53-year-old female with a history of systematic hypertension, diabetes mellitus and hypercholesterolemia presented with left hemiparesis and dysarthria. Angiography of the innominate artery showed a stenosis of the innominate bifurcation. The lesion was successfully treated using the retrograde kissing stent technique via a brachial approach and an exposed direct carotid approach. The retrograde kissing stent technique for the treatment of a stenosis of the innominate bifurcation was found to be a safe and effective alternative to conventional surgery. (orig.)

  15. Das Kindersprachscreening (KiSS) - ein Verfahren zur Sprachstandserfassung vierjähriger Kinder

    NEUMANN, K; Holler-Zittlau, I; Sick, U; Zaretsky, Y; Euler, HA

    2009-01-01

    Einleitung: Zur Feststellung von Sprachförder- oder -therapiebedarf eignet sich ein Sprachscreening, sofern es eine ausreichende Validität aufweist und über streng algorithmische Kriterien zur Auffälligkeitsklassifizierung verfügt. Material und Methode: Für eine hessenweite Erfassung der vorschulischen Sprachkompetenz wurde das psychometrisch geprüfte Kindersprachscreening (KiSS) entwickelt. 257 Kinder im Alter von 4;0 bis 4;5 Jahren wurden mit einer Testbatterie auf ihren Sprachstand ...

  16. Novel adipokinetic hormones in the kissing bugs Rhodnius prolixus, Triatoma infestans, Dipetalogaster maxima and Panstrongylus megistrus

    Marco, H. G.; Šimek, Petr; Clark, K. D.; Gäde, G.

    2013-01-01

    Roč. 41, MAR 10 (2013), s. 21-30. ISSN 0196-9781 R&D Projects: GA MZd(CZ) NT11513 Grant ostatní: National Research Foundation(ZA) IFR 2008071500048; National Research Foundation(ZA) FA 2007021300002 Institutional support: RVO:60077344 Keywords : insects * kissing bugs * reduviidae Subject RIV: ED - Physiology Impact factor: 2.614, year: 2013 http://www.sciencedirect.com/science/article/pii/S0196978112004433

  17. Korea Integrated Seismic System (KISS) and Earthquake Monitoring for Korea Train eXpress (KTX).

    Park, Jung Ho; Chi, Heon Cheol; Seub Lim, In; Kim, Geun Young; Shin, Jin Soo

    2010-05-01

    Since 2002 Korea Integrated Seismic System (KISS) has been playing main role in real-time seismic data exchange between different seismic networks operated by four earthquake monitoring institutes: KMA, KEPRI, KINS and KIGAM. Seismic data from different seismic networks are gathered into the data pool of KISS where clients can receive data in real-time. Before expanding and modernizing of Korean seismic stations, the consortium of the four institutes made the standard criteria of seismic observation such as instrument, data format, and communication protocol for the purpose of integrating seismic networks. More than 160 digital stations (velocity or accelerometer) installed from 1998 to 2009 in Korea could be easily linked to KISS in real time due to the standard criteria. When a big earthquake happens, the observed peak acceleration value can be used as the instrumental intensity on the local site and the distribution of peak accelerations shows roughly the severity of the damaged area. Real Time Intensity Color Mapping (RTICOM) is developed to generate every second contour map of the nationwide intensity based on the peak acceleration values retrieved through KISS from local stations. RTICOM can be used for rapid evaluation of the intensity and decision making against earthquake damages. For the purpose of rapid response to earthquake hazard, Korea Train eXpress (KTX) constructed real-time monitoring system using accelerometers installed on bridges and tunnels. KTX monitoring center receives every second PGA data and monitoring system displays these data on the dedicated screen. The frequency zone of data is considered only below 10 Hz in other to reduce artificial false alarms. If a higher PGA value overcomes the pre-determined level then an alarm will happen with making sound and brightening red and yellow lights. The KTX control center would make repaid decision whether express train should be stopped immediately or not.

  18. Kissing loop interaction in adenine riboswitch: insights from umbrella sampling simulations

    Di Palma, Francesco; Bottaro, Sandro; Bussi, Giovanni

    2015-01-01

    Introduction Riboswitches are cis-acting regulatory RNA elements prevalently located in the leader sequences of bacterial mRNA. An adenine sensing riboswitch cis-regulates adeninosine deaminase gene (add) in Vibrio vulnificus. The structural mechanism regulating its conformational changes upon ligand binding mostly remains to be elucidated. In this open framework it has been suggested that the ligand stabilizes the interaction of the distal "kissing loop" complex. Using accurate full-atom mol...

  19. Technology programme

    The technology activities carried out by the EURATOM-ENEA Association concern the continuation of the European Fusion Development Agreement (EFDA) as well as the ITER activities coordinated by the ITER International Office and Fusion for Energy. Also included in the activities are design and RD under the Broader Approach Agreement between the EU and Japan. In order to better contribute to the programme a number of consortium agreements among the Associations are being signed. Collaboration with industries in view of their participation in the construction of ITER was further strengthened, mainly in the field of magnet and divertor components. The new European Test Blanket Facility at ENEA Brasimone was completed; the design of the ITER radial neutron camera was optimised and the performance achievable with the in-vessel viewing system was further assessed by experimental trials. Design activities for the JT-60SA magnet and power supply system as well as the design and experimental activities related to the target of the International Fusion Materials Irradiation Facility were continued. Significant work was done to define quality assurance for neutronics analyses. Mockups of the ITER pre-compression ring made in glass fibre epoxy were tested. The activities and results documented in the following illustrate ENEA's efforts to support fusion development

  20. The special programme of research in human reproduction: forty years of activities to achieve reproductive health for all.

    Benagiano, Giuseppe; d'Arcangues, Catherine; Harris Requejo, Jennifer; Schafer, Alessandra; Say, Lale; Merialdi, Mario

    2012-01-01

    The Special Programme of Research in Human Reproduction (HRP), co-sponsored by the UNDP, UNFPA, WHO, and the World Bank, is celebrating 40 years of activities with an expansion of its mandate and new co-sponsors. When it began, in 1972, the main focus was on evaluating the acceptability, effectiveness, and safety of existing fertility-regulating methods, as well as developing new, improved modalities for family planning. In 1994, HRP not only made major contributions to the Plan of Action of the International Conference on Population and Development (ICPD); it also broadened its scope of work to include other aspects of health dealing with sexuality and reproduction, adding a specific perspective on gender issues and human rights. In 2002, HRP's mandate was once again broadened to include sexually transmitted infections and HIV/AIDS and in 2003 it was further expanded to research activities on preventing violence against women and its many dire health consequences. Today, the work of the Programme includes research on: the sexual and reproductive health of adolescents, women, and men; maternal and perinatal health; reproductive tract and sexually transmitted infections (including HIV/AIDS); family planning; infertility; unsafe abortion; sexual health; screening for cancer of the cervix in developing countries, and gender and reproductive rights. Additional activities by the Programme have included: fostering international cooperation in the field of human reproduction; the elaboration of WHO's first Global Reproductive Health Strategy; work leading to the inclusion of ICPD's goal 'reproductive health for all by 2015' into the Millennium Development Goal framework; the promotion of critical interagency statements on the public health, legal, and human rights implications of female genital mutilation and gender-biased sex selection. Finally, HRP has been involved in the creation of guidelines and tools, such as the 'Medical eligibility criteria for contraceptive use

  1. The Kiss-and-Run Model of Intra-Golgi Transport

    Alexander A. Mironov

    2012-06-01

    Full Text Available The Golgi apparatus (GA is the main station along the secretory pathway. Mechanisms of intra-Golgi transport remain unresolved. Three models compete with each other for the right to be defined as the paradigm. The vesicular model cannot explain the following: (1 lipid droplets and aggregates of procollagen that are larger than coatomer I (COPI-dependent vesicles are transported across the GA; and (2 most anterograde cargoes are depleted in COPI vesicles. The compartment progression/maturation model has the following problems: (1 most Golgi-resident proteins are depleted in COPI vesicles; (2 there are no COPI vesicles for the recycling of the resident proteins in the trans-most-Golgi cisterna; and (3 different proteins have different rates of intra-Golgi transport. The diffusion model based on permanent inter-cisternal connections cannot explain the existence of lipid, ionic and protein gradients across the Golgi stacks. In contrast, the kiss-and-run model has the potential to explain most of the experimental observations. The kiss-and-run model can be symmetric when fusion and then fission occurs in the same place, and asymmetric when fusion takes place in one location, whereas fission takes place in another. The asymmetric kiss-and-run model resembles the carrier maturation mechanism, and it can be used to explain the transport of large cargo aggregates.

  2. Research programme 'Active Solar Energy Use - Solar Heating and Heat Storage'. Activities and projects 2003; Programme 'Solaire actif - Chaleur et Stockage de chaleur'. Activites et projets en 2003

    Hadorn, J.-C. [Base Consultants, Geneva (Switzerland); Renaud, P. [Planair SA, La Sagne (Switzerland)

    2003-07-01

    In this report by the research, development and demonstration (RD+D) programme coordinators the objectives, activities and main results in the area of solar heating and heat storage in Switzerland are presented for 2003. In a stagnating market environment the strategy of the Swiss Federal Office of Energy mainly consists in improving the quality and durability of solar collectors and materials, optimizing combisystems for space heating and domestic hot water preparation, searching for storage systems with a higher energy storage density than in the case of sensible heat storage in water, developing coloured solar collectors for more architectonic freedom, and finalizing a seasonal heat storage project for 100 dwellings to demonstrate the feasibility of solar fractions larger than 50% in apartment houses. Support was granted to the Swiss Testing Facility SPF in Rapperswil as in previous years; SPF was the first European testing institute to perform solar collector labeling according to the new rules of the 'Solar Keymark', introduced in cooperation with the European Committee for Standardization CEN. Several 2003 projects were conducted within the framework of the Solar Heating and Cooling Programme of the International Energy Agency IEA. Computerized simulation tools were improved. With the aim of jointly producing high-temperature heat and electric power a solar installation including a concentrating collector and a thermodynamic machine based on a Rankine cycle is still being developed. Seasonal underground heat storage was studied in detail by means of a validated computer simulation programme. Design guidelines were obtained for such a storage used in the summer time for cooling and in the winter time for space heating via a heat pump: depending on the ratio 'summer cooling / winter heating', cooling requires a cooling machine, or direct cooling without such a machine is possible. The report ends up with the list of all supported RD

  3. Finnish bioenergy research programme

    Asplund, D. [VTT Energy, Jyvaeskylae (Finland)

    1996-12-31

    Finland is a leading country in the use of biofuels and has excellent opportunities to increase the use of biofuels by up to 25-30 %. The Finnish Government has set an objective for the promotion of bioenergy. The aim is to increase the use of bioenergy by about 25 % from the present level by 2005, and the increment corresponds to 1.5 million tonnes of oil equivalent (toe) per year. The R and D work has been considered as an important factor to achieve this ambitious goal. Energy research was organised into a series of research programmes in 1988 in accordance with the proposal of Finnish Energy Research Committee. The object of the research programmes is to enhance research activities and to bundle individual projects together into larger research packages. The common target of the Finnish energy research programmes is to proceed from basic and applied research to product development and pilot operation, and after that to the first commercial applications, e.g. demonstrations. As the organisation of energy research to programmes has led to good results, the Finnish Ministry of Trade and Industry decided to go on with this practice by launching new six-year programmes in 1993-1998. One of these programmes is the Bioenergy Research Programme and the co-ordination of this programme is carried out by VTT Energy. Besides VTT Energy the Finnish Forest Research Institute, Work Efficiency Institute, Metsaeteho and University of Joensuu are participating in the programme 7 refs.

  4. 2000-2006 National Wood Energy Programme. 2000-2005 Activities Report

    2005 was marked by key decisions which were taken with the aim of developing the biomass sector as a substitute for fossil fuels. Indeed, to achieve the ambitious objectives for renewable sources of energy set out by the July 2005 Energy Policy Orientation Programme (POPE), we must make great use of biomass, particularly to increase by 50% the share of renewable thermal energy between now and 2010 and to enable biofuels to represent 7% of all fuels used at the same date. To a lesser extent, and in conjunction with heat production, the share of biomass in renewable electricity production also needs to rise. Both the resource and key supply players are there and are ready to get organised in order to rise to these challenges. There is an abundant supply of agricultural and forest by-products. More than sixty companies organise and deliver heating wood. More than 300 government and professional promotion, regulatory, PR, finance, equipment construction and operation, research and engineering organizations are involved in this market. The strategic and economic context is highly favourable in the light of laws, directives and international agreements aiming to combat greenhouse gas emissions, but also due to the structural pressure on the price of fossil fuels. Wood energy, as a renewable energy source, has an important role to play in this context of growth. Furthermore, the wood energy sector should be developed using an exemplary sustainable development approach, which means that all the economic, social and environmental effects are taken into account. In order to comprehensively assess the sector's environmental impact, a full chapter of this report presents the work and programmes set up by ADEME to reduce pollutant emissions produced by biomass combustion, particularly from private households. Moreover, consultation and dialogue between those involved must be widened in order to enable all wood users to benefit from 'best forest use' which will be a key

  5. THE FINANCING OF THE ACTIVITIES WITHIN THE SECTORIAL OPERATIONAL PROGRAMME “INCREASE OF ECONOMIC COMPETITIVENESS”

    Vasile POPEANGĂ

    2009-12-01

    Full Text Available The Sectorial Operational Programme “Increase of Economic Competitiveness” (further referred to as SOP IEC is one of the seven instruments (OPs, under the Convergence objective, for achieving the priorities of the National Strategic Reference Framework (NSRF derived from the National Development Plan 2007 – 2013 (NDP, which aims to strengthen the strategic focus of the Economic and Social Cohesion policies across Romania, and to make the correct and appropriate linkages to the European policies and the Lisbon Strategy for growth and job creation. SOP IEC was elaborated under the coordination of the Managing Authority for SOP IEC -Ministry of Economy and Finance (MEF, and is the result of the partnership consultations both with the strategic partners (ACIS within MEF, other MAs–ministries coordinating other OPs, institutions designated as Intermediate Bodies, other line ministries, and agencies, social partners, civil society organizations, potential beneficiaries, other stakeholders involved in this field.

  6. National Wood-fuel Programme 2000-2006. Activity Report 2000-2006

    When ADEME launched its Wood-fuel programme throughout all of France in late 1999, its aim was to guide this resource supply chain to maturity and stable development in all user sectors: domestic, multi-family housing, commercial/institutional and industrial applications. To this end the Wood-fuel Programme 2000-2006 was assigned objectives and endowed with significant financial means for studies and coordination in order to support and carry out general-interest projects, piloted by ADEME. The stated goal was to replace fossil fuels, avoid carbon emissions and establish quality assurance standards for household firewood and wood-fired devices. This report presents: 1 - the Wood Energy stakes for the environment, for employment, and for the economy, the biomass energy net benefits; 2 - the Wood Energy key figures: Production and consumption, Single-family homes and wood heating, Breakdown of types of devices used, Sales of wood-fired devices, Number of housing/institutional boilers in use, Number of industrial boilers in use; 3 - the Wood Energy objectives: Domestic heating, Industrial boiler plants, District heating for housing/institutional/commercial uses; 4 - the Wood Energy program operation: Program coordination by ADEME, Partnerships and State-Region planning agreements, 2000-2006 funding system (modified in 2004) and Other financial instruments; 5 - the 2000-2006 assessment: Main results, Conclusions and recommendations, Evaluation contributions: five key points, Evaluation of employment in the solid biofuels supply chain, Supply for community, institutional and commercial boilers; 6 - Information and communication: Initiatives supported or accompanied by ADEME between 2000 and 2004, Publications supported by ADEME. In appendix: fuels and energy content, regional assessments, national research program on bio-energies - PNRB 2006 (Review and stakes, PNRB results in 2006), wood heating R and D, studies funded by ADEME, 2006 ADEME's correspondents, glossary

  7. Emotional competencies of the sport coach: A qualitative approach within a physical activity programme for multiple sclerosis patients. A case study

    Mouton, Alexandre; Defossa, Clément; Cloes, Marc

    2010-01-01

    The main purposes of this study were to describe the intervention and to link emotional competencies and behaviors of the coach in a physical activity programme for MS patients. We wanted also to close this study proposing recommendations to improve MS patient physical activity management.

  8. Risoe activity within the CEC SOFC programme: Measurement of internal stresses by neutron diffraction

    The objective was to design, fabricate and test a neutron diffraction equipment for measurements of internal stresses in SOFC components with high spatial resolution, and use the best suited equipment to measure internal stresses in SOFC components from other participants in the programme. Two different geometries and two different materials (Al2Ox and YSZ) were examined in order to investigate: the diffracted intensity as related to the diffracting volume, the diffracted intensity as related to the position of the sample relative to the slit arrangement, and the accuracy of the strain measurement. It was found that the beam collimation by two pairs of double slits increases and the diffraction efficiency decreases with decreased slit width, the diffracting volume is fairly well defined by the two pairs of double slits, and the accuracy in the determination of the internal stresses is adequate. With the equipment for high spatial resolution it is possible to measure lattice spacing in volumes of YSZ down to 1-10 mm3. Residual strains were measured for NiO, LSM and YSZ of a planar Risoe 3-layer cell (anode NiO/YSZ, electrode YSZ, cathode LMS/YSZ). Each layer was 42 by 42 by 0.1 mm. Slit widths from 10 to 20 mm were used. The best suited equipment was a combination of Soller slits (thin, neutron absorbing, parallel plates) and a double slit for both the incident and the diffracted beam. The measured residual strains for the components of the cell are: 300x10-6 (tension) for NiO, 700x10-6 (tension) for LSM and less than 450x10-6 (compression) for YSZ. (AB)

  9. Summary of nuclear model calculations for the IAEA coordinated research programme on activation cross sections for fusion reactor technology

    We describe research performed for the International Atomic Energy Agency (IAEA) Coordinated Research Programme on activation cross sections for fusion reactor technology. Using the GNASH nuclear modeling code, we have investigated: (1) production cross sections of isomeric states, and isomer ratios, for the reactions 94Mo(n,p)94Nb, 109Ag(n,2n)108mAg, 151Eu(n,2n)150m Eu, 153Eu(n,2n)152g+m2Eu, 159Tb(n,2n)158Tb, 187Re(n,2n)186mRe, 179Hf(n,2n)178m2Hf, 193Ir(n,2n)192m2Ir; (2) systematical dependence of isomeric ratios on isomer spin and incident-energy; (3) preequilibrium spin effects on calculated isomer production; and (4) intercomparison and evaluation of nuclear model excitation functions of isomer production cross sections. (author). 16 refs, 8 figs, 1 tab

  10. Unravelling the Evolution of the Allatostatin-Type A, KISS and Galanin Peptide-Receptor Gene Families in Bilaterians: Insights from Anopheles Mosquitoes.

    Rute C Felix

    Full Text Available Allatostatin type A receptors (AST-ARs are a group of G-protein coupled receptors activated by members of the FGL-amide (AST-A peptide family that inhibit food intake and development in arthropods. Despite their physiological importance the evolution of the AST-A system is poorly described and relatively few receptors have been isolated and functionally characterised in insects. The present study provides a comprehensive analysis of the origin and comparative evolution of the AST-A system. To determine how evolution and feeding modified the function of AST-AR the duplicate receptors in Anopheles mosquitoes, were characterised. Phylogeny and gene synteny suggested that invertebrate AST-A receptors and peptide genes shared a common evolutionary origin with KISS/GAL receptors and ligands. AST-ARs and KISSR emerged from a common gene ancestor after the divergence of GALRs in the bilaterian genome. In arthropods, the AST-A system evolved through lineage-specific events and the maintenance of two receptors in the flies and mosquitoes (Diptera was the result of a gene duplication event. Speciation of Anopheles mosquitoes affected receptor gene organisation and characterisation of AST-AR duplicates (GPRALS1 and 2 revealed that in common with other insects, the mosquito receptors were activated by insect AST-A peptides and the iCa2+-signalling pathway was stimulated. GPRALS1 and 2 were expressed mainly in mosquito midgut and ovaries and transcript abundance of both receptors was modified by feeding. A blood meal strongly up-regulated expression of both GPRALS in the midgut (p < 0.05 compared to glucose fed females. Based on the results we hypothesise that the AST-A system in insects shared a common origin with the vertebrate KISS system and may also share a common function as an integrator of metabolism and reproduction.AST-A and KISS/GAL receptors and ligands shared common ancestry prior to the protostome-deuterostome divergence. Phylogeny and gene

  11. Elevated expression of KiSS-1 in placenta of Chinese women with early-onset preeclampsia.

    Chong Qiao

    Full Text Available Preeclampsia (PE is a heterogeneous syndrome affecting 2% to 8% of all pregnancies and is the world's leading cause of fetal and maternal morbidity and mortality. In many cases of PE, shallow trophoblast invasion results in inappropriate maternal spiral artery remodeling and impaired placental function. Multiple genes have been implicated in trophoblast invasion, among which are KiSS-1 and GPR54. The gene product of KiSS-1 is metastin, which is a ligand for the receptor GPR54. Both metastin and GPR54 are expressed in the placenta of normal pregnancy and have been implicated in modulating trophoblast invasion through inhibiting migration of trophoblast cells. We have previously reported that the expression level of KiSS-1 was higher in trophoblasts from women with preeclampsia as compared to normal controls. Here, using quantitative RT-PCR, Western blot analysis and immunohistochemistry, we extend our analysis to demonstrate that elevated KiSS-1 expression occurs only in early-onset preeclampsia (ePE and not late-onset preeclampsia (lPE. However, no difference in the expression levels of GPR54 is observed between ePE, lPE, and normal controls. Further, we show that KiSS-1 expression is also increased in placenta of intrauterine death and birth asphyxia in comparison to normal newborns of ePE and lPE. Our findings suggest that aberrant upregulation of KiSS-1 expression may contribute to the underlying mechanism of ePE as well as birth asphyxia.

  12. Requirements for kissing-loop-mediated dimerization of human immunodeficiency virus RNA.

    Clever, J L; Wong, M L; Parslow, T G

    1996-01-01

    Sequences from the 5' end of type 1 human immunodeficiency virus RNA dimerize spontaneously in vitro in a reaction thought to mimic the initial step of genomic dimerization in vivo. Dimer initiation has been proposed to occur through a "kissing-loop" interaction involving a specific RNA stem-loop element designated SL1: the RNA strands first interact by base pairing through a six-base GC-rich palindrome in the loop of SL1, whose stems then isomerize to form a longer interstrand duplex. We now...

  13. Endovascular Treatment of Blunt Traumatic Abdominal Aortic Occlusion With Kissing Stent Placement

    Idoguchi, Koji, E-mail: idoguchi@ares.eonet.ne.jp; Yamaguchi, Masato; Okada, Takuya [Kobe University Hospital, Department of Radiology and Center for Endovascular Therapy (Japan); Nomura, Yoshikatsu [Kobe University Hospital, Department of Cardiovascular Surgery (Japan); Sugimura, Kazuro [Kobe University Hospital, Department of Radiology and Center for Endovascular Therapy (Japan); Okita, Yutaka [Kobe University Hospital, Department of Cardiovascular Surgery (Japan); Sugimoto, Koji [Kobe University Hospital, Department of Radiology and Center for Endovascular Therapy (Japan)

    2012-10-15

    Blunt traumatic abdominal aortic dissection is extremely rare and potentially deadly. We present the case of a 62-year-old man involved in a frontal car crash. After emergency undergoing laparotomy for bowel injuries, he was referred to our hospital due to acute ischemia of bilateral lower extremities on day 3 after the trauma. Computed tomography and aortography showed an aortobiiliac dissection with complete occlusion. This injury was successfully treated by endovascular treatment with 'kissing'-technique stent placement, which appears to be a safe, effective, and minimally invasive treatment.

  14. Aberrant Expression of Kiss-1 and Matrix Metalloproteinase-9 Are Closely Linked to Lymph Node Metastasis of Gastric Cancer

    Hua-chuan Zheng; Ai-ming Yu; Yan Xin

    2008-01-01

    @@ China is one of the countries with the highest risk of gastric cancer over the past century, which is still the lead-ing cause of death worldwide. Because metastatic disease of gastric cancer is the most critical impediment to patient survival, it is necessary to further understand the molecular mechanisms of its metastasis. Kiss-1, mapping to chromo-some lq32, is one of these genes regulated at chromosome 6. Kiss-1 expression was discovered to inhibit metastasis in both in vivo melanoma and breast carcinoma models.

  15. 对“Kiss Lands Iranian Actress and Director in Court”的译文的几点看法

    于德兰

    2003-01-01

    读吴来哉选译的文章“Kiss Lands Iranian Actress and Director in Court”(贵刊2002年第11期),发现译文在表达上尚存缺憾。现简析如下,与吴教授切磋。A kiss planted on the forehead of a young Iranian director by a well-known actress has landed the pair in court and sparked heated protest in the Islamic Republic over physical contact between the sexes.

  16. Changes in muscle activity after performing the FIFA 11+ programme part 2 for 4 weeks.

    Takata, Yasushi; Nakase, Junsuke; Inaki, Anri; Mochizuki, Takafumi; Numata, Hitoaki; Oshima, Takeshi; Kinuya, Seigo; Tsuchiya, Hiroyuki

    2016-10-01

    Changes in muscle activity were evaluated by positron emission tomography-computed tomography (PET-CT) after performing part 2 of the Fédération Internationale de Football Association's 11+ programme (11+) for 4 weeks. Eleven males performed part 2 of the 11+ for 20 min before and after 37 MBq of (18)F-fluorodeoxyglucose (FDG) was injected intravenously. PET-CT images were obtained 50 min after FDG injection. The participants were then instructed to perform part 2 of the 11+ 3 times per week for 4 consecutive weeks, after which another set of PET-CT images was obtained following the same procedure. Regions of interest were defined within 30 muscles. The standardised uptake value (SUV) of FDG by muscle tissue per unit volume was calculated, and FDG accumulation was compared between pre- and post-training PET-CT results. Performing part 2 of the 11+ for 4 weeks increased mean SUV in the sartorius, semimembranosus, biceps femoris, abductor hallucis, and flexor hallucis brevis muscles (P < 0.05). In conclusion, routinely performing part 2 of the 11+ for 4 weeks increased glucose uptake related to muscle activity in the hamstrings and hallux muscles. We speculate that there is some possibility of this change of muscle activity contributing to a decrease in sports-related injuries. PMID:26911842

  17. Effect of the Great Activity Programme on healthy lifestyle behaviours in 7-11 year olds.

    Morris, John G; Gorely, Trish; Sedgwick, Matthew J; Nevill, Alan; Nevill, Mary E

    2013-01-01

    The study investigated the effect of a school-based healthy lifestyles intervention on physical activity and dietary variables. In total 378 children (177 intervention, 201 control; age 9.75 ± 0.82 years (mean ± s)) took part in the 7-month intervention comprising: preparation for and participation in 3 highlight events (a dance festival, a walking event and a running event); an interactive website for pupils, teachers and parents; and vacation activity planners. Primary outcome measures were objectively measured physical activity (pedometers and accelerometers), endurance fitness and dietary variables. Multi-level modelling was employed for data analysis. The increase in physical activity was greater in the intervention group than the control group (steps: 1049 vs 632 daily steps each month; moderate to vigorous physical activity (MVPA) total: 4.6 min · day(-1) · month(-1) vs 1.3 min · day(-1) · month(-1); MVPA bouts: 5.4 min · day(-1) · month(-1) vs 2.6 min · day(-1) · month(-1); all P children. PMID:23656302

  18. European Identity through Space Space Activities and Programmes as a Tool to Reinvigorate the European Identity

    Baranes, Blandina

    2013-01-01

    Space activities are one particularly visible area, where Europe can shape its identity. This publication investigates the effect space activities have already had on building a European “spirit” (e.g. through European missions or European astronauts). It also looks into the effects that activities labelled “national” have on the emergence of a European identity. Based on this analysis, the book's intention is to identify creative ways and means for how to further use space for shaping the European identity. For this purpose the focus is not only on policy analysis but also on expertise from the fields of cultural science and the arts in order to tap their creative potential and also their theoretical approaches to the topic. Selecting this theme provides ESPI with another opportunity to develop its trans-disciplinary approach.

  19. New Euratom research programme 2002-2006

    Mustonen, R. [Radiation and Nuclear Safety Authority, Helsinki (Finland)

    2003-06-01

    The European Union funded research is carried out under two distinct programmes; the European Community Framework Programme (EC Programme) covering research, technological development and demonstration activities; and the Euratom Framework Programme covering research and training activities in the nuclear sector. The contents, funding and timetable of the sixth Euratom Framework Programme (FP6) are shortly reviewed in this paper. The European Union (EU) FP6 for the years 2002 - 2006 starts at the beginning of the year 2003.

  20. The kissing-loop T-shaped structure translational enhancer of Pea enation mosaic virus can bind simultaneously to ribosomes and a 5' proximal hairpin.

    Gao, Feng; Gulay, Suna P; Kasprzak, Wojciech; Dinman, Jonathan D; Shapiro, Bruce A; Simon, Anne E

    2013-11-01

    The Pea enation mosaic virus (PEMV) 3' translational enhancer, known as the kissing-loop T-shaped structure (kl-TSS), binds to 40S subunits, 60S subunits, and 80S ribosomes, whereas the Turnip crinkle virus (TCV) TSS binds only to 60S subunits and 80S ribosomes. Using electrophoretic mobility gel shift assay (EMSA)-based competition assays, the kl-TSS was found to occupy a different site in the ribosome than the P-site-binding TCV TSS, suggesting that these two TSS employ different mechanisms for enhancing translation. The kl-TSS also engages in a stable, long-distance RNA-RNA kissing-loop interaction with a 12-bp 5'-coding-region hairpin that does not alter the structure of the kl-TSS as revealed by molecular dynamics simulations. Addition of the kl-TSS in trans to a luciferase reporter construct containing either wild-type or mutant 5' and 3' PEMV sequences suppressed translation, suggesting that the kl-TSS is required in cis to function, and both ribosome-binding and RNA interaction activities of the kl-TSS contributed to translational inhibition. Addition of the kl-TSS was more detrimental for translation than an adjacent eIF4E-binding 3' translational enhancer known as the PTE, suggesting that the PTE may support the ribosome-binding function of the kl-TSS. Results of in-line RNA structure probing, ribosome filter binding, and high-throughput selective 2'-hydroxyl acylation analyzed by primer extension (hSHAPE) of rRNAs within bound ribosomes suggest that kl-TSS binding to ribosomes and binding to the 5' hairpin are compatible activities. These results suggest a model whereby posttermination ribosomes/ribosomal subunits bind to the kl-TSS and are delivered to the 5' end of the genome via the associated RNA-RNA interaction, which enhances the rate of translation reinitiation. PMID:23986599

  1. Programmable SERS active substrates for chemical and biosensing applications using amorphous/crystalline hybrid silicon nanomaterial

    Jeffery Alexander Powell; Krishnan Venkatakrishnan; Bo Tan

    2016-01-01

    We present the creation of a unique nanostructured amorphous/crystalline hybrid silicon material that exhibits surface enhanced Raman scattering (SERS) activity. This nanomaterial is an interconnected network of amorphous/crystalline nanospheroids which form a nanoweb structure; to our knowledge this material has not been previously observed nor has it been applied for use as a SERS sensing material. This material is formed using a femtosecond synthesis technique which facilitates a laser plu...

  2. Design of a process evaluation of the implementation of a physical activity and sports stimulation programme in Dutch rehabilitation setting : ReSpAct

    Hoekstra, Femke; Alingh, Roelina A.; van der Schans, Cees P.; Hettinga, Florentina J.; Duijf, Marjo; Dekker, Rienk; van der Woude, Lucas H. V.

    2014-01-01

    Background: There is a growing interest to study the transfer of evidence-based information into daily practice. The evidence-based programme Rehabilitation, Sports and Exercise (RSE) that aims to stimulate an active lifestyle during and after a rehabilitation period in people with a disability and/

  3. Cost-Effectiveness of a Long-Term Internet-Delivered Worksite Health Promotion Programme on Physical Activity and Nutrition: A Cluster Randomized Controlled Trial

    Robroek, Suzan J. W.; Polinder, Suzanne; Bredt, Folef J.; Burdorf, Alex

    2012-01-01

    This study aims to evaluate the cost-effectiveness of a long-term workplace health promotion programme on physical activity (PA) and nutrition. In total, 924 participants enrolled in a 2-year cluster randomized controlled trial, with departments (n = 74) within companies (n = 6) as the unit of randomization. The intervention was compared with a…

  4. Valve-Like and Protruding Calcified Intimal Flap Complicating Common Iliac Arteries Kissing Stenting

    George S. Georgiadis

    2015-01-01

    Full Text Available Endovascular therapy for iliac artery chronic total occlusions is nowadays associated with low rates of procedure-related complications and improved clinical outcomes, and it is predominantly used as first-line therapy prior to aortobifemoral bypass grafting. Herein, we describe the case of a patient presenting with an ischemic left foot digit ulcer and suffering complex aortoiliac lesions, who received common iliac arteries kissing stents, illustrating at final antegrade and retrograde angiograms the early recognition of a blood flow obstructing valve-like calcified intimal flap protruding through the stent struts, which was obstructing antegrade but not retrograde unilateral iliac arterial axis blood flow. The problem was resolved by reconstructing the aortic bifurcation at a more proximal level. Completion angiogram verified normal patency of aorta and iliac vessels. Additionally, a severe left femoral bifurcation stenosis was also corrected by endarterectomy-arterioplasty with a bovine patch. Postintervention ankle brachial pressure indices were significantly improved. At the 6-month and 2-year follow-up, normal peripheral pulses were still reported without intermittent claudication suggesting the durability of the procedure. Through stent-protruding calcified intimal flap, is a very rare, but existing source of antegrade blood flow obstruction after common iliac arteries kissing stents.

  5. Valve-Like and Protruding Calcified Intimal Flap Complicating Common Iliac Arteries Kissing Stenting

    Georgiadis, George S.; Georgakarakos, Efstratios I.; Schoretsanitis, Nikolaos; Argyriou, Christos C.; Antoniou, George A.; Lazarides, Miltos K.

    2015-01-01

    Endovascular therapy for iliac artery chronic total occlusions is nowadays associated with low rates of procedure-related complications and improved clinical outcomes, and it is predominantly used as first-line therapy prior to aortobifemoral bypass grafting. Herein, we describe the case of a patient presenting with an ischemic left foot digit ulcer and suffering complex aortoiliac lesions, who received common iliac arteries kissing stents, illustrating at final antegrade and retrograde angiograms the early recognition of a blood flow obstructing valve-like calcified intimal flap protruding through the stent struts, which was obstructing antegrade but not retrograde unilateral iliac arterial axis blood flow. The problem was resolved by reconstructing the aortic bifurcation at a more proximal level. Completion angiogram verified normal patency of aorta and iliac vessels. Additionally, a severe left femoral bifurcation stenosis was also corrected by endarterectomy-arterioplasty with a bovine patch. Postintervention ankle brachial pressure indices were significantly improved. At the 6-month and 2-year follow-up, normal peripheral pulses were still reported without intermittent claudication suggesting the durability of the procedure. Through stent-protruding calcified intimal flap, is a very rare, but existing source of antegrade blood flow obstruction after common iliac arteries kissing stents. PMID:26783493

  6. Greek Teachers Programme 2015

    Hoch, Michael

    2015-01-01

    The 3rd edition of this year's Greek Teachers Programme was co-organized by CERN Education Group and the Hellenic Physical Society and took place from 8 to 12 November 2015. The programme targets physics high-school teachers from all over Greece. It aims to help teachers inspire the next generation of scientists and engineers by motivating their students to understand and appreciate how science works at the world's largest physics laboratory, whereby increasing their interest in pursuing studies in STEM fields in secondary and post-secondary education. 33 teachers took part in this programme which comprised lectures by Greek members of the CERN scientific community, with visits to experimental facilities, hands-on activities and dedicated sessions on effective and creative ways through which participants may bring physics, particle physics and CERN closer to their school classroom. In 2015, more than 100 teachers took part in the three editions of the Greek Teachers Programme.

  7. Programmable SERS active substrates for chemical and biosensing applications using amorphous/crystalline hybrid silicon nanomaterial

    Powell, Jeffery Alexander; Venkatakrishnan, Krishnan; Tan, Bo

    2016-01-01

    We present the creation of a unique nanostructured amorphous/crystalline hybrid silicon material that exhibits surface enhanced Raman scattering (SERS) activity. This nanomaterial is an interconnected network of amorphous/crystalline nanospheroids which form a nanoweb structure; to our knowledge this material has not been previously observed nor has it been applied for use as a SERS sensing material. This material is formed using a femtosecond synthesis technique which facilitates a laser plume ion condensation formation mechanism. By fine-tuning the laser plume temperature and ion interaction mechanisms within the plume, we are able to precisely program the relative proportion of crystalline Si to amorphous Si content in the nanospheroids as well as the size distribution of individual nanospheroids and the size of Raman hotspot nanogaps. With the use of Rhodamine 6G (R6G) and Crystal Violet (CV) chemical dyes, we have been able to observe a maximum enhancement factor of 5.38 × 106 and 3.72 × 106 respectively, for the hybrid nanomaterial compared to a bulk Si wafer substrate. With the creation of a silicon-based nanomaterial capable of SERS detection of analytes, this work demonstrates a redefinition of the role of nanostructured Si from an inactive to SERS active role in nano-Raman sensing applications.

  8. Molecular identification of Kiss/GPR54 and function analysis with mRNA expression profiles exposure to 17α-ethinylestradiol in rare minnow Gobiocypris rarus.

    Yang, Yanping; Gao, Jiancao; Yuan, Cong; Zhang, Yingying; Guan, Yongjing; Wang, Zaizhao

    2016-07-01

    17α-ethinylestradiol (EE2) is a widely existed endocrine disrupting chemical in water environment. Kisspeptins act as indispensable regulators through GPR54 in the hypothalamic-pituitary-gonadal (HPG) axis. This study aimed to provide further understanding of the effect of EE2 on HPG axis. Molecular cloning and tissue distribution of kiss genes and GPR54s were performed in Gobiocypris rarus. The mRNA expression profiles of kiss1, kiss2, GPR54s and GnRHs were detected in G. rarus brain and/or gonad following 3- and 6-days EE2 (1, 5, 25 and 125 ng/L) exposure. Results showed that kiss genes and GPR54s were highly expressed in brain and gonad. Both kiss1 and kiss2 were increased in female brain and suppressed in male brain following EE2 exposure. GnRHs were inhibited in a concentration-dependent manner in male brain following 3-days EE2 exposure. In gonad, GPR54b was almost suppressed in all of EE2 concentrations. The present findings suggest that EE2 impacts the genes expression of Kiss/GPR54-GnRH system in G. rarus, thereby probably disturbing the neuroendocrine homeostasis. PMID:27216535

  9. Applications of instrumental neutron activation analysis (INAA) for geological samples in AMD for uranium exploration programme

    Full text: Non-destructive Instrumental Neutron Activation Analysis has been used over last three decades in AMD for analysis of geological samples for estimation of Na, K, Ca, Sc, Cr, Fe, Co, Cu, Zn, Ga, As, Br, Zr, Ag, Sb, Cs, Ba, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Tm, Ho, Yb, Lu, Hf, Ta, W, Re, Os, Ir, Au, Th and U. The estimation has been done using various international standards. The irradiation of samples has been done in Cirus/Apsara Reactor in BARC, Mumbai. The measurement of desired gamma emission are carried out by Huge detector. The various geological samples from different parts of India are: 1. granites 2. charnokites 3. Basalts 4. Carbonatites 5. Xenotime 6. Monazite 7. Core samples 8. Black slabs. The efficiency modelling of HPGe detector was done using different sources and mathematical and statistical techniques. (author)

  10. Comparative analysis of kisspeptin-immunoreactivity reveals genuine differences in the hypothalamic Kiss1 systems between rats and mice

    Overgaard, Agnete; Tena-Sempere, Manuel; Franceschini, Isabelle;

    2013-01-01

    kisspeptin-immunoreactivity in both nuclei and both sexes of rats and mice and quantified kisspeptin-immunoreactive nerve fibers. We also determined Kiss1 mRNA levels and measured kisspeptin-immunoreactivity in colchicine pretreated rats. Overall, we find higher levels of kisspeptin-immunoreactivity in the...

  11. Activating welfare recipients with health complaints: Reasons for failure of a cognitive training programme

    Inge Bramsen

    2011-03-01

    Een groeiende nadruk op de activering van uitkeringsgerechtigden heeft in veel Westerse verzorgingsstaten geleid tot de ontwikkeling van interventies die gericht zijn op uitkeringsgerechtigden met gezondheidsklachten. Vormen van dwang, zoals verplichte participatie, worden meer en meer toegepast binnen dit activeringsbeleid. Een voorbeeld hiervan is het Nederlandse project “Gezond aan de Slag”, dat een interventie ontwikkelde en evalueerde waarin een fysiek trainingsprogramma gecombineerd wordt met cognitieve training. Hoewel HtW als “best practice” gold, liet een randomized trial geen positieve effecten van de interventie zien. Omdat het cognitieve trainingsprogramma, gebaseerd op rationeel-emotieve therapie, niet eerder afzonderlijk werd bestudeerd, werd een diepgaande kwalitatieve studie uitgevoerd. Getracht werd om de oorzaken van het falen van het programma in kaart te brengen. Zes, gericht geselecteerde, trainers werden geïnterviewd. De resultaten lieten zien dat de trainers problemen hadden met de heterogeniteit van de deelnemersgroep en op andere problemen, verwachtingen en arbeidsmarktobstakels stuitten dan vooraf verwacht. De verplichte aard van HtW had een negatief effect op de motivatie van zowel deelnemers als trainers. In de discussieparagraaf van dit artikel worden vraagtekens geplaatst bij de veronderstelling dat de coping stijl en cognities van uitkeringsgerechtigden met gezondheidsproblemen de belangrijkste hindernissen zijn voor het vinden van werk, en worden vraagtekens geplaatst bij het beleid om fysieke beperkingen van deelnemers te negeren. De auteurs suggereren dat met betrekking tot dit complexe praktijkprobleem, verbetering kan worden bereikt door aanpassen en leren van de interventie gedurende de toepassing daarvan toe te staan, en door expliciet te reflecteren op de normatieve aspecten van de interventie, en de perspectieven van de uitkeringsgerechtigden zelf.

  12. Review of fast reactor physics activities relevant to LMFBR programme in PNC, Japan, June 1976 - May 1977

    Fast reactor physics activities performed during a year from June, 1976, to May, 1977, along with the programme in PNC are reviewed. The first topic is the start up of JOYO which attained the criticality on April 24, 1977. Present status of the design of MONJU and the design study of the demonstration fast breeder reactor are briefly reviewed in the second part. The rest of this report presents the results of more specific studies as follows. (1) Mockup experiment in FCA and analysis to support MONJU design. (2) Parameter study on the breeding characteristics of a 1000 MWe class LMFBR. (3) Evaluation of actinide nuclear data. (4) Detailed analysis of sodium void experiments. (5) The improvement of LSQ program for sensitivity analysis. (6) Effect of size of the critical mockup on the extrapolation errors in predicting neutronic properties of a 1000 MWe core. (7) Research on the two-dimensional calculational method for shielding, and application to MONJU design and to the evaluation of neutrons streaming through a primary sodium duct of JOYO. (Aoki, K.)

  13. Evaluation of beta spectrometry for environmental monitoring of undeclared nuclear activities. Report on task FIN A846 on the Finnish support programme to IAEA safeguards

    The IAEA (the Agency) is considering environmental monitoring as a possible method to detect the presence of undeclared nuclear activities in a country covered by a comprehensive safeguards agreement. The Finnish support program (FINSP), implemented by the Finnish Centre for Radiation and Nuclear Safety (STUK), is supporting the Agency in this new programme. This Agency Task FIN A 846, addresses the possibility of using beta-emitting nuclides as indicators for covert nuclear fuel reprocessing activities. (90 refs., 1 fig., 12 tabs.)

  14. Intervention dose estimation in health promotion programmes: a framework and a tool. Application to the diet and physical activity promotion PRALIMAP trial

    Legrand Karine

    2012-09-01

    Full Text Available Abstract Background Although the outcomes of health promotion and prevention programmes may depend on the level of intervention, studies and trials often fail to take it into account. The objective of this work was to develop a framework within which to consider the implementation of interventions, and to propose a tool with which to measure the quantity and the quality of activities, whether planned or not, relevant to the intervention under investigation. The framework and the tool were applied to data from the diet and physical activity promotion PRALIMAP trial. Methods A framework allowing for calculation of an intervention dose in any health promotion programme was developed. A literature reviews revealed several relevant concepts that were considered in greater detail by a multidisciplinary working group. A method was devised with which to calculate the dose of intervention planned and that is actually received (programme-driven activities dose, as well as the amount of non-planned intervention (non-programme-driven activities dose. Results Indicators cover the roles of all those involved (supervisors, anchor personnel as receivers and providers, targets, in each intervention-related groups (IRG: basic setting in which a given intervention is planned by the programme and may differ in implementation level and for every intervention period. All indicators are described according to two domains (delivery, participation in two declensions (quantity and quality. Application to PRALIMAP data revealed important inter- and intra-IRG variability in intervention dose. Conclusions A literature analysis shows that the terminology in this area is not yet consolidated and that research is ongoing. The present work provides a methodological framework by specifying concepts, by defining new constructs and by developing multiple information synthesis methods which must be introduced from the programme's conception. Application to PRALIMAP underlined the

  15. VIP in construction: systematic development and evaluation of a multifaceted health programme aiming to improve physical activity levels and dietary patterns among construction workers

    Viester Laura

    2012-01-01

    Full Text Available Abstract Background The prevalence of both overweight and musculoskeletal disorders (MSD in the construction industry is high. Many interventions in the occupational setting aim at the prevention and reduction of these health problems, but it is still unclear how these programmes should be designed. To determine the effectiveness of interventions on these health outcomes randomised controlled trials (RCTs are needed. The aim of this study is to systematically develop a tailored intervention for prevention and reduction of overweight and MSD among construction workers and to describe the evaluation study regarding its (cost-effectiveness. Methods/Design The Intervention Mapping (IM protocol was applied to develop and implement a tailored programme aimed at the prevention and reduction of overweight and MSD. The (cost- effectiveness of the intervention programme will be evaluated using an RCT. Furthermore, a process evaluation will be conducted. The research population will consist of blue collar workers of a large construction company in the Netherlands. Intervention The intervention programme will be aimed at improving (vigorous physical activity levels and healthy dietary behaviour and will consist of tailored information, face-to-face and telephone counselling, training instruction (a fitness "card" to be used for exercises, and materials designed for the intervention (overview of the company health promoting facilities, waist circumference measuring tape, pedometer, BMI card, calorie guide, recipes, and knowledge test. Main study parameters/endpoints The intervention effect on body weight and waist circumference (primary outcome measures, as well as on lifestyle behaviour, MSD, fitness, CVD risk indicators, and work-related outcomes (i.e. productivity, sick leave (secondary outcome measures will be assessed. Discussion The development of the VIP in construction intervention led to a health programme tailored to the needs of construction

  16. Monitoring programme

    Her Majesty's Inspectorate of Pollution's 1992 report on its programme of monitoring radioactive substances is presented. Site operators' returns are verified and the report provides independent data on the environmental impact of authorized disposal of radioactive wastes. Radiation doses which may have been received by members of the public, fall well below the International Commission for Radiological Protection's (ICRP) recommended annual doses. (UK)

  17. VizieR Online Data Catalog: Metal abundances of KISS galaxies. V. (Hirschauer+, 2015)

    Hirschauer, A. S.; Salzer, J. J.; Bresolin, F.; Saviane, I.; Yegorova, I.

    2016-01-01

    Our spectroscopic targets for this project were potentially metal-rich galaxies identified by KPNO International Spectroscopic Survey (KISS; Salzer et al., 2000AJ....120...80S). KISS used low-dispersion objective-prism spectra to identify emission-line galaxy (ELG) candidates via detection of line emission in galaxies with redshifts of less than 0.095. The "red" survey (Salzer et al. 2001, cat. J/AJ/121/66; Gronwall et al. 2004, cat. J/AJ/127/1943; Jangren et al. 2005, cat. J/AJ/130/2571) cataloged objects by means of the Hα line, while the "blue" survey (Salzer et al. 2002, cat. J/AJ/123/1292) distinguished objects through strong [OIII]λ5007 line emission. The 15 galaxies discussed in this paper were chosen from the KISS Hα-selected catalog. Spectra of 15 KISS ELGs were obtained using the Keck I 10m telescope on 2006 May 25 with the Low-Resolution Imaging Spectrometer (LRIS), a double spectrograph that includes a dichroic that directs light toward a red and a blue side. The use of two distinct dispersion elements and cameras enables simultaneous spectral coverage spanning from ~3000 to ~10000Å with good dispersion. Blue side exposures used the 600/400 grism, with a dispersion of 0.63Å/pixel, a resolution of ~6Å, and wavelength coverage between ~3000 and ~5600Å. Red side exposures used the 900/5500 grating, with a dispersion of 0.53Å/pixel, a resolution of ~3Å, and wavelength coverage between ~5700 and ~7300Å. Each galaxy was first observed using the blue and red sides simultaneously to determine if further observations would yield usable spectra. If the raw spectra were of substantially high quality, the red side grating was switched to observe near-infrared (NIR) lines. This was completed for ten of the fifteen galaxies. For NIR exposures, the red side was switched to the 400/8500 grating, with a dispersion of 1.16Å/pixel, a resolution of ~6Å, and wavelength coverage between ~6300 and ~10000Å in order to observe the NIR [SIII] nebular lines at λ9069

  18. Syphilitic Chancre of the Lips Transmitted by Kissing: A Case Report and Review of the Literature.

    Yu, Xin; Zheng, Heyi

    2016-04-01

    Primary syphilic chancre most often involved genitalia, with 12% to 14% extragenital lesions. This article describes a rare case of a female patient with labial ulcer and diagnosed as oral syphilis (OS), an uncommon presentation of primary syphilis. OS is transmitted through orogenital contact.This study is case report and literature review.We report a 27-year-old woman with painless, ulcerative, and indurated lesion on her lower lip and a 7-day history of symmetrically distributed nonpruritic macules. OS was diagnosed based on clinical presentations and serologic test and patient's oral ulcer was cured with intramuscular penicillin G benzathine. However, both the patient and her husband denied any orogenital sexual history before. In addition, her husband was also diagnosed as syphilis later in our clinic. He reported having orogenital contact with other people.Therefore, this is a rare case of OS transmitted through kissing. PMID:27057901

  19. Hierarchy of kissing numbers for exceptional Lie symmetry groups in high energy physics

    We are constructing a hierarchy of kissing numbers representing singular contact points of hyper-spheres in exceptional Lie symmetry groups lattice arrangement embedded in the 26 dimensional bosonic strings spacetime. That way we find a total number of points and dimensions equal to 548. This is 52 more than the order of E8E8 of heterotic string theory and leads to the prediction of 69 elementary particles at an energy scale under 1 T. In other words, our mathematical model predicts nine more particles than what is currently experimentally known to exist in the standard model of high energy physics namely only 60. The result is thus in full agreement with all our previous theoretical findings

  20. Investigations on tunneling and kissing bond defects in FSW joints for dissimilar aluminum alloys

    Khan, Noor Zaman, E-mail: noor_0315@yahoo.com [Department of Mechanical Engineering, Jamia Millia Islamia (A Central University), New Delhi (India); Siddiquee, Arshad Noor; Khan, Zahid A. [Department of Mechanical Engineering, Jamia Millia Islamia (A Central University), New Delhi (India); Shihab, Suha K. [Department of Mechanical Engineering, Engineering College, Diyala University, Diyala (Iraq)

    2015-11-05

    In this paper an attempt has been made to investigate the effect of two Friction Stir Welding (FSW) parameters i.e. tool pin offset and tool plunge depth on the formation of defects such as tunnel (tunneling defect) and kissing bond (KB) during welding of dissimilar aluminum alloys. 4.75 mm thick plates of AA5083-H116 and AA6063-T6 were welded using a novel work-fixture developed in-house which, apart from clamping the plated also imparted continuous variation of offset on both side of the faying line. The tunneling defect was modeled as a function of offset and plunge depth. The welds were characterised using optical microscopy (OM), scanning electron microscopy (SEM) and mechanical testing. The causes of such defects have been analyzed and discussed and recommendations have been made to prevent their occurrence. The findings of the study have revealed that the tunneling defects are formed at all offset (including zero offset) values towards stronger material (advancing side). And the cross-section of the tunnel varied with the amount of offset. Further, KBs are formed at the interface for all pin offset values except 0.5 mm towards weaker material and high plunge depth resulting in the poor mechanical properties. - Highlights: • Two dissimilar aluminum alloys are welded using FSW. • Formation of kissing bond and tunneling defects are investigated. • Defects are formed at pin offsets towards stronger material and also without offset. • The size of tunnel reduces significantly by increasing the plunge depth. • Tool pin offset towards weaker material prevent tunneling defects.

  1. Investigations on tunneling and kissing bond defects in FSW joints for dissimilar aluminum alloys

    In this paper an attempt has been made to investigate the effect of two Friction Stir Welding (FSW) parameters i.e. tool pin offset and tool plunge depth on the formation of defects such as tunnel (tunneling defect) and kissing bond (KB) during welding of dissimilar aluminum alloys. 4.75 mm thick plates of AA5083-H116 and AA6063-T6 were welded using a novel work-fixture developed in-house which, apart from clamping the plated also imparted continuous variation of offset on both side of the faying line. The tunneling defect was modeled as a function of offset and plunge depth. The welds were characterised using optical microscopy (OM), scanning electron microscopy (SEM) and mechanical testing. The causes of such defects have been analyzed and discussed and recommendations have been made to prevent their occurrence. The findings of the study have revealed that the tunneling defects are formed at all offset (including zero offset) values towards stronger material (advancing side). And the cross-section of the tunnel varied with the amount of offset. Further, KBs are formed at the interface for all pin offset values except 0.5 mm towards weaker material and high plunge depth resulting in the poor mechanical properties. - Highlights: • Two dissimilar aluminum alloys are welded using FSW. • Formation of kissing bond and tunneling defects are investigated. • Defects are formed at pin offsets towards stronger material and also without offset. • The size of tunnel reduces significantly by increasing the plunge depth. • Tool pin offset towards weaker material prevent tunneling defects

  2. Optogenetic Stimulation of Arcuate Nucleus Kiss1 Neurons Reveals a Steroid-Dependent Glutamatergic Input to POMC and AgRP Neurons in Male Mice.

    Nestor, Casey C; Qiu, Jian; Padilla, Stephanie L; Zhang, Chunguang; Bosch, Martha A; Fan, Wei; Aicher, Sue A; Palmiter, Richard D; Rønnekleiv, Oline K; Kelly, Martin J

    2016-06-01

    Kisspeptin (Kiss1) neurons are essential for reproduction, but their role in the control of energy balance and other homeostatic functions remains unclear. Proopiomelanocortin (POMC) and agouti-related peptide (AgRP) neurons, located in the arcuate nucleus (ARC) of the hypothalamus, integrate numerous excitatory and inhibitory inputs to ultimately regulate energy homeostasis. Given that POMC and AgRP neurons are contacted by Kiss1 neurons in the ARC (Kiss1(ARC)) and they express androgen receptors, Kiss1(ARC) neurons may mediate the orexigenic action of testosterone via POMC and/or AgRP neurons. Quantitative PCR analysis of pooled Kiss1(ARC) neurons revealed that mRNA levels for Kiss1 and vesicular glutamate transporter 2 were higher in castrated male mice compared with gonad-intact males. Single-cell RT-PCR analysis of yellow fluorescent protein (YFP) ARC neurons harvested from males injected with AAV1-EF1α-DIO-ChR2:YFP revealed that 100% and 88% expressed mRNAs for Kiss1 and vesicular glutamate transporter 2, respectively. Whole-cell, voltage-clamp recordings from nonfluorescent postsynaptic ARC neurons showed that low frequency photo-stimulation (0.5 Hz) of Kiss1-ChR2:YFP neurons elicited a fast glutamatergic inward current in POMC and AgRP neurons. Paired-pulse, photo-stimulation revealed paired-pulse depression, which is indicative of greater glutamate release, in the castrated male mice compared with gonad-intact male mice. Group I and group II metabotropic glutamate receptor agonists depolarized and hyperpolarized POMC and AgRP neurons, respectively, which was mimicked by high frequency photo-stimulation (20 Hz) of Kiss1(ARC) neurons. Therefore, POMC and AgRP neurons receive direct steroid- and frequency-dependent glutamatergic synaptic input from Kiss1(ARC) neurons in male mice, which may be a critical pathway for Kiss1 neurons to help coordinate energy homeostasis and reproduction. PMID:27093227

  3. Co-ordinated research and environmental surveillance programme related to sea disposal of radioactive waste CRESP activity report 1986-1990

    The Co-ordinated Research and Environmental Surveillance Programme relevant to sea disposal of radioactive waste (CRESP) was created in 1981 in the framework of the 1977 Decision of the OECD Council establishing a Multilateral Consultation and Surveillance Mechanism for Sea Dumping of Radioactive Waste. The main task of CRESP was to set up a site-specific scientific research programme to increase current knowledge of the processes controlling the transfer of radionuclides in the marine environment, so that impact of past dumping could be monitored and future assessments could be based on more accurate and comprehensive scientific data. The CRESP mandate was extended in 1987 to respond to a request from the Paris Commission to include consideration of radioactive discharges in the maritime area covered by the Convention on the Prevention of Marine Pollution from Land-Based Sources. This report summarizes the CRESP activities carried out during the 1986-1990 five year phase. Concerning the review of deep sea results, the report relates progress achieved above the level of knowledge which was available when the present phase of the CRESP programme was decided and which has been taken into account in the 1985 Site Suitability Review. With respect to coastal discharges, it presents a summary of R and D work undertaken by member countries, including those carried out in other programmes such as MARINA. Finally, it makes proposals for future work within CRESP

  4. Effects of 6-month soccer and traditional physical activity programmes on body composition, cardiometabolic risk factors, inflammatory, oxidative stress markers and cardiorespiratory fitness in obese boys.

    Seabra, André; Katzmarzyk, Peter; Carvalho, Maria José; Seabra, Ana; Coelho-E-Silva, Manuel; Abreu, Sandra; Vale, Susana; Póvoas, Susana; Nascimento, Henrique; Belo, Luís; Torres, Sandra; Oliveira, José; Mota, Jorge; Santos-Silva, Alice; Rêgo, Carla; Malina, Robert M

    2016-10-01

    Physical activity is important in obesity prevention, but the effectiveness of different physical activity modalities remains to be determined among children. The main purpose of this study was to compare the effects of a 6-month soccer programme and a traditional physical activity programme on changes in body composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status in obese boys. Eighty-eight boys (8-12 years; BMI > +2 standard deviations of WHO reference values) participated in one of three groups: soccer, traditional activity and control. Soccer and traditional activity programmes involved 3 sessions per week for 60-90 min at an average intensity of 70-80% of maximal heart rate. Control group participated in activities of normal daily living. All boys participated in school physical education, two sessions per week of 45-90-min. Measurements were taken at baseline and after 6 months, and included body size and composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status. Physical activity and dietary intake were assessed before and immediately following the intervention. The three groups had similar characteristics at baseline. After 6 months, both intervention groups had significantly lower relative fatness (% fat), waist circumference and total cholesterol, and higher cardiorespiratory fitness, self-esteem, perceived physical competence and attraction to physical activity compared with control group. In conclusion, physical activity interventions over 6 months positively influenced several indicators of health status among obese boys. The results also suggested that soccer has the potential as an effective tool for the prevention and reduction of childhood obesity and associated consequences. PMID:26890580

  5. ADS National Programmes: France

    Studies related to nuclear reactors and radioactive waste started at the French National Centre for Scientific research, CNRS, as a result of the French law on radioactive waste that was published in 1991. They were initially organized around the programme PACE (Physique pour l’Aval du Cycle Electronucléaire = physics of the back end of the nuclear fuel cycle), which became PACEN (Physique pour l’Aval du Cycle et production d’Energie Nucléaire = Physics of the back end of the nuclear fuel cycle and production of nuclear energy) in 2006. Research on accelerator driven systems was from the beginning part of this programme. This research is mainly funded by the National Institute for Nuclear end Particle Physics (IN2P3) of CNRS and within the EURATOM European programmes (FP5, 6 and 7). The programme took place in several stages, and covered various scientific fields, benefitting from expertise of CNRS in the field. More specifically, it aimed and still aims to: – Test and verify the feasibility and design of the ADS concept, in terms of neutronics, physics of materials, design of the accelerator and tests of its prototypical components that have been built (or are at present under construction); – Measure and-or improve nuclear data related to radioactive waste transmutation. Today, most of the activities in support to ADS development carried out by CNRS focus on accelerator developments, GUINEVERE (Generator of Uninterrupted Intense NEutron at the lead VEnus REactor) experiment, ADS core studies, deployment scenarios and nuclear data measurements. The CEA R&D programmes on ADS are mainly focused on the European project EUROTRANS of the 6th Framework programme (2005–2010) and continued in the FREYA project of the 7th Framework Programme

  6. SET-Routes programme

    Marietta Schupp, EMBL Photolab

    2008-01-01

    Dr Sabine Hentze, specialist in human genetics, giving an Insight Lecture entitled "Human Genetics – Diagnostics, Indications and Ethical Issues" on 23 September 2008 at EMBL Heidelberg. Activities in a achool in Budapest during a visit of Angela Bekesi, Ambassadors for the SET-Routes programme.

  7. Evaluation of an individualised programme to promote self-care in sleep-activity in patients with coronary artery disease - a randomised intervention study

    Johansson, Anna; Adamson, Anita; Ejdeback, Jan; Edéll-Gustafsson, Ulla

    2014-01-01

    Aims and objectives. To evaluate the effectiveness of an individualised programme to promote self-care in sleep-activity in patients with coronary artery disease. Background. Recent scientific findings have shown that low physical exercise and stress interfere with coronary artery disease patients sleep quality and sleep efficiency independent of gender, age and co-morbidity. Design. A randomised pretest-post-test control design. Methods. Forty-seven patients who had undergone a coronary reva...

  8. Policies to Accelerate Fuel, Technology andBehavioural Change in Transport - Results and Success of the Austrian Climate: Active Mobile Programme after the First Seven Years

    There is plenty of concepts and strategies on almost all administrative levels to reduce carbon emissions and boost energy efficiency in transport. But it usually takes a long time to adapt national and regional legislation to these strategies with considerable loss of valuable time. Furthermore some of the defined measures will never find the necessary ''political will'' for implementation. To bridge this gap Austria's Environmental ministry supported by the Austrian Energy Agency, got into action 2005 and set up an action programme, condensing all so called ''soft'' and ''voluntary'' measures in transport (''mobility management''), that do not necessarily need to wait for legislation or specific administrative framework conditions. In its comprehensive approach - not only transport is targeted, but also buildings, renewables and energy saving - and also in its effects regarding the reduction of GHG emissions, Climate:active and especially climate:active mobile seems to be one-of-a-kind in Europe. Climate-active mobile set-up: free-of-charge consulting programmes addressing specific target groups (companies, cites andmunicipalities, real estate developers, schools andyouth, tourism); a financial support programme with 51 Mio Euro since 2007 for mobility management measures, fleet conversions to low-carbon technologies, work travel plans etc.; an EcoDriving training programme with up to now 20,000 trainees and educating all novice drivers in Austria in a smart driving style; a broad awareness raising campaign; about 2,900 klima:aktiv mobil partners among the target groups implementing sustainable transport measures and therewith reduces more than 530,000 tons of CO2 emissions every year, created or saved 4300 ''green jobs'' in transport and induced ''green'' investments by companies and administrations 7 to 8 times higher as the funding. Climate-active mobile is one of the main drivers in Austria to accelerate fuel, technology andbehavioural change in transport and

  9. The effect of a ten month physical activity intervention programme on body composition of 9-13 year-old boys

    Malan, Dawid Daniel Jacobus; Monyeki, Makama Andries; Toriola, Abel; Van Ridder, Johannes Hendrik; Du Preez, Susanna Maria

    2012-01-01

    Excessive body fat is one of the main contributing factors in many health related health debilitating diseases, such as diabetes, obesity, hypertension and coronary arterioscleroses. The objective of this study was to determine whether a ten month physical activity intervention (PAI) programme could alter the body composition of 9-13 year old boys. A total of 322 (173=experimental group (EG) and 149=control group (CG)) from two primary schools in Gauteng province of South Africa were studied....

  10. Feasibility and acceptability of a midwife-led intervention programme called 'Eat Well Keep Active' to encourage a healthy lifestyle in pregnancy

    Warren Lucie

    2012-04-01

    Full Text Available Abstract Background Eating a diet that is high in fat and sugar and having a sedentary lifestyle during pregnancy is understood to increase the risk of excessive gestational weight gain and obesity following the birth of the baby. However, there are no clinical guidelines in the UK on what is considered to be appropriate gestational weight gain. Indeed, clinical recommendations discourage the routine re-weighing of pregnant women, stating instead that women should be advised regarding their diet and activity levels, in order to prevent excessive weight gain. Pregnancy is seen as a time when many women may have an increased motivation to improve their lifestyle behaviours for the benefit of the fetus. However, it is evident that many women have difficulty in both maintaining a healthy balanced diet and remaining active through pregnancy. It would seem that midwives may be ideally placed to assist women to make and maintain healthier lifestyle choices during pregnancy. Methods/design This study will look at the feasibility and acceptability of a newly devised intervention programme called 'Eat Well Keep Active'. Participants will complete a questionnaire prior to the programme to obtain baseline data on food frequency, physical activity and to gauge their perception of personal ability to improve/maintain healthy lifestyle. The programme comprises client centred techniques; motivational interviewing and goal setting delivered early in pregnancy (12-16 weeks with the aim of supporting a healthy well balanced diet and either continuing or commencing appropriate levels of physical activity. Participants will then be followed up six weeks following the intervention with a one-to-one interview, and a further brief questionnaire. The interview will provide preliminary data regarding perceived effectiveness and acceptability of the 'Eat Well Keep Active' programme whilst the questionnaire will provide data regarding changes in the confidence of

  11. The duplicated longitudinal epiphysis or ''kissing delta phalanx'': evolution and variation in three different disorders

    Elliott, Alison M. [Department of Biochemistry and Medical Genetics, University of Manitoba, 770 Bannatyne Avenue, R3E 0W3, Winnipeg, Manitoba (Canada); Evans, Jane A.; Chudley, Albert E. [Department of Biochemistry and Medical Genetics, University of Manitoba, 770 Bannatyne Avenue, R3E 0W3, Winnipeg, Manitoba (Canada); Department of Pediatrics and Child Health, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba (Canada); Reed, Martin H. [Department of Biochemistry and Medical Genetics, University of Manitoba, 770 Bannatyne Avenue, R3E 0W3, Winnipeg, Manitoba (Canada); Department of Pediatrics and Child Health, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba (Canada); Department of Radiology, University of Manitoba and Health Sciences Centre, Winnipeg, Manitoba (Canada)

    2004-06-01

    The delta phalanx, also known as the delta bone, or longitudinal epiphyseal bracket (LEB), has been described in a variety of syndromes and dysplasias. However, the ''kissing delta phalanx'' is not as well recognized in the literature; it consists of a duplicated longitudinal bracketed epiphysis, or a complex of two adjacent delta bones, with opposing convex portions facing each other. Magnetic resonance imaging of the kissing delta phalanx has not been previously described. To describe the evolution, variation and associated osseous anomalies of the kissing delta phalanx in three patients with distinct distal limb malformations using both plain films and magnetic resonance imaging. Patient 1 had Rubinstein-Taybi syndrome and, in addition to a kissing delta phalanx in both feet, had corresponding delta metatarsals (MT1). Patient 2 had Cenani-Lenz syndactyly with distinct variation of the kissing delta phalanx in each hand. He had a disorganized appearance to the phalanges, metacarpal fusions and carpal coalitions. Patient 3 had an isolated oligosyndactyly of the left hand with metacarpal fusions and carpal coalitions. All three patients were followed over time. We describe two types of kissing delta phalanges: separated (without fusion of the corresponding epiphyseal brackets) and nonseparated (with fusion of the corresponding epiphyseal brackets). Both types can be seen in the same patient and are a reflection of the relative degree of segmentation of the two delta bones. (orig.)

  12. IDIOPATHIC THORACO SCOLIOSIS TREATMENT USING A COMBINATION OF DOCUMENTATION BASED CARE (DBC BACK ACTIVE RECONDITIONING PROGRAMME AND SCHROTH METHODS: A PROSPECTIVE CASE STUDY

    Ganesan Kathiresan

    2013-10-01

    Full Text Available reconditioning programme and Schroth methods to lessen the curvature allied with idiopathic Thoracicscoliosis.ResearchDesign: Sampling-An 18 years old female, single case study,Setting-DBC Kuching Active rehabilitationcentre, Malaysia.Duration of the study-20 weeks,Outcome measures-A base line and follow-up outcomemeasures includes Borg pain scale, Functional Rating Index, Balance test, and Radiographic analysis.Interventions-Document Based Care (DBC Back active reconditioning programme and Schroth methodsConclusion-The combination of the Document Based Care (DBC Back active reconditioning programme andSchroth methods seemed to be effective at reducing a Thoracic dextroscoliosis by about 14° (50% andLumbarLevoscoliosis by about 7° (25%, Short form (SF-36 showed improvement inQuality of life,balance time on theBalance board improved to 52 seconds and Borg pain scale rated 8/10 at the onset of care, dropped to a 1/10after 20 weeks, in this single case study. The positive outcomes of this practice validate a policyof offeringconservative treatment as an alternative to Thoracic scoliosis patients, including those for whom surgery isdiscussed

  13. ADS National Programmes: Germany

    The German R&D programme for ADS development is related to the partitioning and transmutation of spent fuel. This programme is implemented mainly by the three national research centres belonging to the Helmholtz Association, i.e. Karlsruhe Institute of Technology (KIT), Forschungszentrum Jülich (FZJ) in cooperation with the Technical University of Aachen (RWTH Aachen) and the Helmholtz Zentrum Dresden Rossendorf (HZDR). The main purpose of this R&D programme is the prospect to manage the high level radioactive waste such as to reduce the burden on a final repository. P&T does not eliminate the need for a final repository whatever the strategy, but it allows the reduction of the radio-toxicity associated with radioactive waste, the increase of the repository capacity as a consequence of the reduction of masses to be stored and their associated residual heat load. Different fuel cycle scenarios to implement P&T can be envisaged. These scenarios have been evaluated to identify the impact of P&T on the characteristics, number and deployment pace of the installations of the fuel cycle (reprocessing, fuel fabrication, storage etc). Almost all activities conducted in the R&D programme are embedded in European and international projects and initiatives. In the following more details on the relevant components of the R&D programme are summarized

  14. Development and implementation of a lifestyle intervention to promote physical activity and healthy diet in the Dutch general practice setting: the BeweegKuur programme

    de Vries Nanne K

    2010-05-01

    Full Text Available Abstract Background The number of patients with diabetes is increasing. BeweegKuur (Dutch for 'Exercise Therapy' is a Dutch lifestyle intervention which aims to effectively and feasibly promote physical activity and better dietary behaviour in primary health care to prevent diabetes. Methods The goal of this paper is to present the development process and the contents of the intervention, using a model of systematic health promotion planning. The intervention consists of a 1-year programme for diabetic and prediabetic patients. Patients are referred by their general practitioner (GP to a lifestyle advisor (LSA, usually the practice nurse or a physiotherapist. Based on specific inclusion criteria and in close collaboration with the patient, an individual exercise programme is designed and supervised by the LSA. This programme can be attended at existing local exercise facilities or (temporarily under the supervision of a specialized exercise coach or physiotherapist. All participants are also referred to a dietician and receive diet-related group education. In the first pilot year (2008, the BeweegKuur programme was implemented in 7 regions in the Netherlands (19 GP practices and health centres, while 14 regions (41 GP practices and health centres participated during the second year. The aim is to implement BeweegKuur in all regions of the Netherlands by 2012. Discussion The BeweegKuur programme was systematically developed in an evidence- and practice-based process. Formative monitoring studies and (controlled effectiveness studies are needed to examine the diffusion process and the effectiveness and cost-effectiveness of the intervention.

  15. Re-thinking global health sector efforts for HIV and tuberculosis epidemic control: promoting integration of programme activities within a strengthened health system

    Maher Dermot

    2010-07-01

    Full Text Available Abstract Background The global financial crisis threatens global health, particularly exacerbating diseases of inequality, e.g. HIV/AIDS, and diseases of poverty, e.g. tuberculosis. The aim of this paper is to reconsider established practices and policies for HIV and tuberculosis epidemic control, aiming at delivering better results and value for money. This may be achieved by promoting greater integration of HIV and tuberculosis control programme activities within a strengthened health system. Discussion HIV and tuberculosis share many similarities in terms of their disease burden and the recommended stratagems for their control. HIV and tuberculosis programmes implement similar sorts of control activities, e.g. case finding and treatment, which depend for success on generic health system issues, including vital registration, drug procurement and supply, laboratory network, human resources, and financing. However, the current health system approach to HIV and tuberculosis control often involves separate specialised services. Despite some recent progress, collaboration between the programmes remains inadequate, progress in obtaining synergies has been slow, and results remain far below those needed to achieve universal access to key interventions. A fundamental re-think of the current strategic approach involves promoting integrated delivery of HIV and tuberculosis programme activities as part of strengthened general health services: epidemiological surveillance, programme monitoring and evaluation, community awareness of health-seeking behavior, risk behaviour modification, infection control, treatment scale-up (first-line treatment regimens, drug-resistance surveillance, containing and countering drug-resistance (second-line treatment regimens, research and development, global advocacy and global partnership. Health agencies should review policies and progress in HIV and tuberculosis epidemic control, learn mutual lessons for policy

  16. Cloning of the Chicken KISS-1 Like Gene and the Expression Analysis of EST Sequence%鸡类KISS-1基因克隆及EST序列表达验证分析

    韩威; 苏一军; 朱云芬; 宋迟; 李国辉; 屠云洁; 张会永; 殷建梅

    2014-01-01

    性成熟启动是一个复杂的生理过程,受“下丘脑-垂体-性腺”轴控制.决定性成熟启动的关键性事件是下丘脑促性腺激素释放激素(GnRH)脉冲式释放增加,KISS-1基因编码产物Kisspeptin通过其受体GPR54能够直接刺激GnRH释放,进而启动性成熟进程,KISS-1/GPR54系统被认为是性成熟启动的关键看门基因.禽类的KISS-1基因在GenBank中尚未被清晰注释.本文以文昌鸡为素材,采用比较基因组学方法分析了不同物种KISS-1及其上、下游基因在染色体上的分布,确定了鸡chr26:1522493-1532710区域为候选片段,通过PCR扩增和克隆测序获得了该候选片段完整序列(命名为类KISS-1序列);同时,采用BLAST程序搜索出9个同源性在50%~85%的EST序列,通过拼接得到3个延伸EST序列.表达验证分析表明,3个延伸EST序列在文昌鸡下丘脑组织cDNA文库中均有表达.

  17. Project Energize: whole-region primary school nutrition and physical activity programme; evaluation of body size and fitness 5 years after the randomised controlled trial.

    Rush, Elaine; McLennan, Stephanie; Obolonkin, Victor; Vandal, Alain C; Hamlin, Michael; Simmons, David; Graham, David

    2014-01-28

    Project Energize, a region-wide whole-school nutrition and physical activity programme, commenced as a randomised controlled trial (RCT) in the period 2004-6 in 124 schools in Waikato, New Zealand. In 2007, sixty-two control schools were engaged in the programme, and by 2011, all but two of the 235 schools in the region were engaged. Energizers (trained nutrition and physical activity specialists) work with eight to twelve schools each to achieve the goals of the programme, which are based on healthier eating and enhanced physical activity. In 2011, indices of obesity and physical fitness of 2474 younger (7·58 (sd 0·57) years) and 2330 older (10·30 (sd 0·51) years) children attending 193 of the 235 primary schools were compared with historical measurements. After adjusting for age, sex, ethnicity, socio-economic status (SES) and school cluster effects, the combined prevalence of obesity and overweight among younger and older children in 2011 was lower by 31 and 15 %, respectively, than that among 'unEnergized' children in the 2004 to 2006 RCT. Similarly, BMI was lower by 3·0 % (95 % CI - 5·8, - 1·3) and 2·4 % (95 % CI - 4·3, - 0·5). Physical fitness (time taken to complete a 550 m run) was significantly higher in the Energized children (13·7 and 11·3 %, respectively) than in a group of similarly aged children from another region. These effects were observed for boys and girls, both indigenous Māori and non-Māori children, and across SES. The long-term regional commitment to the Energize programme in schools may potentially lead to a secular reduction in the prevalence of overweight and obesity and gains in physical fitness, which may reduce the risk of developing obesity and type 2 diabetes. PMID:23867069

  18. The ProActive trial protocol – a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766

    Ekelund Ulf

    2004-10-01

    Full Text Available Abstract Background Increasing prevalence of obesity and disorders associated with sedentary living constitute a major global public health problem. While previous evaluations of interventions to increase physical activity have involved communities or individuals with established disease, less attention has been given to interventions for individuals at risk of disease. Methods/design ProActive aims to evaluate the efficacy of a theoretical, evidence- and family-based intervention programme to increase physical activity in a sedentary population, defined as being at-risk through having a parental family history of diabetes. Primary care diabetes or family history registers were used to recruit 365 individuals aged 30–50 years, screened for activity level. Participants were assigned by central randomisation to three intervention programmes: brief written advice (comparison group, or a psychologically based behavioural change programme, delivered either by telephone (distance group or face-to-face in the family home over one year. The protocol-driven intervention programme is delivered by trained facilitators, and aims to support increases in physical activity through the introduction and facilitation of a range of self-regulatory skills (e.g. goal setting. The primary outcome is daytime energy expenditure and its ratio to resting energy expenditure, measured at baseline and one year using individually calibrated heart rate monitoring. Secondary measures include self-report of individual and family activity, psychological mediators of behaviour change, physiological and biochemical correlates, acceptability, and costs, measured at baseline, six months and one year. The primary intention to treat analysis will compare groups at one-year post randomisation. Estimation of the impact on diabetes incidence will be modelled using data from a parallel ten-year cohort study using similar measures. Discussion ProActive is the first efficacy trial of an

  19. An O(n^5) algorithm for MFE prediction of kissing hairpins and 4-chains in nucleic acids

    Chen, Ho-Lin; CONDON, ANNE; Jabbari, Hosna

    2009-01-01

    Efficient methods for prediction of minimum free energy (MFE) nucleic secondary structures are widely used, both to better understand structure and function of biological RNAs and to design novel nano-structures. Here, we present a new algorithm for MFE secondary structure prediction, which significantly expands the class of structures that can be handled in O(n^5) time. Our algorithm can handle H-type pseudoknotted structures, kissing hairpins, and chains of four overlapping stems, as well a...

  20. Mutations of the Kissing-Loop Dimerization Sequence Influence the Site Specificity of Murine Leukemia Virus Recombination In Vivo

    Mikkelsen, Jacob Giehm; Lund, Anders H.; Duch, Mogens; Pedersen, Finn Skou

    2000-01-01

    The genetic information of retroviruses is retained within a dimeric RNA genome held together by intermolecular RNA-RNA interactions near the 5′ ends. Coencapsidation of retrovirus-derived RNA molecules allows frequent template switching of the virus-encoded reverse transcriptase during DNA synthesis in newly infected cells. We have previously shown that template shifts within the 5′ leader of murine leukemia viruses occur preferentially within the kissing stem-loop motif, a cis element cruci...

  1. IAEA research reactors activities - small research reactors, their role as first step in nuclear technology programme, and cooperation to maximize utilization

    A large number of the existing research reactors in the world are currently under utilized, in many cases because of an overly narrow assessment on the need for the research reactors at the time they were acquired, and an absence of mechanisms to ensure sustainability. On the other hand, operating and utilizing research reactor is often taken as a first step in the preparation for nuclear power program, as both the former and the latter require personnel with similar skills sets and the support of the same/similar infrastructure including regulatory body. This presentation summarizes activities conducted by member states under IAEA's Research Reactor programmes, with more focused discussion on three areas: Reduction in the use of HEU in research reactors;The role of low power critical facilities and small research reactor as a a first step in the development of nuclear energy programmes; and The need for international and regional cooperation to maximize utilization of existing research reactor facilities.

  2. Referral from primary care to a physical activity programme: establishing long-term adherence? A randomized controlled trial. Rationale and study design

    Puig-Ribera Anna

    2009-01-01

    Full Text Available Abstract Background Declining physical activity is associated with a rising burden of global disease. There is little evidence about effective ways to increase adherence to physical activity. Therefore, interventions are needed that produce sustained increases in adherence to physical activity and are cost-effective. The purpose is to assess the effectiveness of a primary care physical activity intervention in increasing adherence to physical activity in the general population seen in primary care. Method and design Randomized controlled trial with systematic random sampling. A total of 424 subjects of both sexes will participate; all will be over the age of 18 with a low level of physical activity (according to the International Physical Activity Questionnaire, IPAQ, self-employed and from 9 Primary Healthcare Centres (PHC. They will volunteer to participate in a physical activity programme during 3 months (24 sessions; 2 sessions a week, 60 minutes per session. Participants from each PHC will be randomly allocated to an intervention (IG and control group (CG. The following parameters will be assessed pre and post intervention in both groups: (1 health-related quality of life (SF-12, (2 physical activity stage of change (Prochaska's stages of change, (3 level of physical activity (IPAQ-short version, (4 change in perception of health (vignettes from the Cooperative World Organization of National Colleges, Academies, and Academic Associations of Family Physicians, COOP/WONCA, (5 level of social support for the physical activity practice (Social Support for Physical Activity Scale, SSPAS, and (6 control based on analysis (HDL, LDL and glycated haemoglobin. Participants' frequency of visits to the PHC will be registered over the six months before and after the programme. There will be a follow up in a face to face interview three, six and twelve months after the programme, with the reduced version of IPAQ, SF-12, SSPAS, and Prochaska's stages

  3. The effects of a home-based arm ergometry exercise programme on physical fitness, fatigue and activity in polio survivors: protocol for a randomised controlled trial

    Murray Deirdre

    2012-12-01

    Full Text Available Abstract Background Many Polio survivors have reduced mobility, pain and fatigue, which make access to conventional forms of aerobic exercise difficult. Inactivity leads to increased risk of health problems, many of which are prevalent among Polio survivors. Aerobic exercise programmes in Polio survivors should utilise stable muscle groups and should be designed to minimise exacerbation of pain and fatigue. A home-based arm ergometry aerobic exercise programme may represent an affordable and accessible exercise modality, incorporating exercise prescription principles in this group. Methods/design This is a prospective, single blinded, randomised controlled trial. There are two arms; exercise intervention using arm ergometers and control. Polio survivors meeting eligibility criteria will be recruited and randomly allocated to intervention or control groups. Participants allocated to the intervention group will receive a small arm ergometer and a polar heart rate monitor. They will carry out a home-based moderate intensity (50-70% HRMax aerobic exercise programme for eight weeks, following instruction by the treating physiotherapist. Assessments will occur at baseline and after eight weeks and will include tests of physical fitness, activity, energy cost of walking, fatigue and quality of life. Clinically feasible assessment tools including the Six Minute Arm Test, the Physical Activity Scale for People with Physical Disabilities questionnaire, the Physiological Cost Index, Fatigue Severity Scale and the SF-36v2 will be utilised. Discussion The efficacy of a home-based arm ergometry programme in Polio survivors will be examined. No previous trial has examined such a programme using a wide range of outcome measures pertinent to Polio survivors. This study will provide new information on the impact of arm ergometry on physical fitness, activity, body composition, fatigue, pain, muscle strength, and health related quality of life. Also, the study

  4. Novel FGFR1 and KISS1R Mutations in Chinese Kallmann Syndrome Males with Cleft Lip/Palate

    Xu, Hao; Niu, Yonghua; Wang, Tao; Liu, Simin; Xu, Hua; Wang, Shaogang; Liu, Jihong; Ye, Zhangqun

    2015-01-01

    Kallmann syndrome (KS) is characterized by isolated hypogonadotropic hypogonadism (IHH) with anosmia and is sometimes associated with cleft lip/palate (CLP). In order to describe the clinical features, genetic etiology, and treatment outcome of KS males with CLP, we performed genetic screening for 15 known causal IHH genes (KAL1, FGFR1, NELF, FGF8, CHD7, WDR11, SEMA3A, KISS1R, KISS1, PROKR2, PROK2, TAC3, TACR3, GNRH1, and GNRHR) in four KS with CLP patients and six IHH patients without CLP. Two novel heterozygous missense mutations in FGFR1, (NM_001174066): c.776G>A (p.G259E) and (NM_001174066): c.358C>T (p.R120C), were identified in a 23-year-old KS male with cleft lip and an 18-year-old KS patient with cleft lip and palate, dental agenesis, and high arched palate, respectively. These two mutations were not presented in their healthy parents and 200 normal controls. One novel heterozygous missense mutation in KISS1R, (NM_032551): c.587C>A (p.P196H), was identified in an 18-year-old KS male with cleft lip and dental agenesis who developed sperm after being treated with gonadotropin. This mutation was also presented in his healthy father and grandfather. These results have implications for the diagnosis, genetic counseling, and treatment of KS and CLP males with mutations in FGFR1 gene. PMID:26199944

  5. Teaching outdoor and adventure activities: describing, analysing and understanding a primary school physical education professional development programme

    Coulter, Maura

    2012-01-01

    Background: Primary schools need well informed and highly motivated teachers to meet the evolving demands of the education system. Professional development is essential to equip primary school teachers to change practice to meet these challenges (Guskey, 2003; Villegas-Reimers, 2003). The purpose of this study was to describe, analyse and understand teachers’ and children’s experiences of a contextualised, whole school professional development programme (PDP) in primary physical education. ...

  6. The Kissing-Loop T-Shaped Structure Translational Enhancer of Pea Enation Mosaic Virus Can Bind Simultaneously to Ribosomes and a 5′ Proximal Hairpin

    Gao, Feng; Gulay, Suna P.; Kasprzak, Wojciech; Dinman, Jonathan D.

    2013-01-01

    The Pea Enation Mosaic Virus (PEMV) 3′ translational enhancer, known as the kissing-loop T-shaped structure (kl-TSS), binds to 40S subunits, 60S subunits, and 80S ribosomes, whereas the Turnip crinkle virus (TCV) TSS binds only to 60S subunits and 80S ribosomes. Using electrophoretic mobility gel shift assay (EMSA)-based competition assays, the kl-TSS was found to occupy a different site in the ribosome than the P-site-binding TCV TSS, suggesting that these two TSS employ different mechanisms for enhancing translation. The kl-TSS also engages in a stable, long-distance RNA-RNA kissing-loop interaction with a 12-bp 5′-coding-region hairpin that does not alter the structure of the kl-TSS as revealed by molecular dynamics simulations. Addition of the kl-TSS in trans to a luciferase reporter construct containing either wild-type or mutant 5′ and 3′ PEMV sequences suppressed translation, suggesting that the kl-TSS is required in cis to function, and both ribosome-binding and RNA interaction activities of the kl-TSS contributed to translational inhibition. Addition of the kl-TSS was more detrimental for translation than an adjacent eIF4E-binding 3′ translational enhancer known as the PTE, suggesting that the PTE may support the ribosome-binding function of the kl-TSS. Results of in-line RNA structure probing, ribosome filter binding, and high-throughput selective 2′-hydroxyl acylation analyzed by primer extension (hSHAPE) of rRNAs within bound ribosomes suggest that kl-TSS binding to ribosomes and binding to the 5′ hairpin are compatible activities. These results suggest a model whereby posttermination ribosomes/ribosomal subunits bind to the kl-TSS and are delivered to the 5′ end of the genome via the associated RNA-RNA interaction, which enhances the rate of translation reinitiation. PMID:23986599

  7. A theory evaluation of an induction programme

    Kenrick Hendricks

    2012-07-01

    Full Text Available Orientation: An induction programme is commonly used to help new employees understand their job within the organisation. Research purpose: The main aim of this study was to examine whether or not the programme theory of an induction programme was plausible and would lead to the intended outcomes as described by the programme manager.Motivation for the study: Induction training is one of the most common training programmes in an organisation. However, there is little research to evaluate whether or not the activities of an induction programme will lead to the intended outcomes of such a programme.Research design, approach and method: This theory evaluation used a descriptive design. One hundred and thirteen employees of a media company completed a ten-item, five-point Likert scale which measured their perceptions of the programme’s outcome, identification with the organisation and intentions to stay with the organisation.Main findings: From this theory evaluation it was apparent that an induction programme based on an implausible programme theory could be problematic. An implausible programme theory affects the design of the programme activities and unsuitable activities may not deliver the desired outcomes.Practical/managerial implications: The intention of the evaluation is to guide human resource managers through a process of replacing an implausible programme theory with one that is plausible, and which ensures better alignment of programme activities and outcomes.Contribution/value-add: The evaluators showed how a plausible programme theory could improve programme design. This redesigned induction programme may lead to benefits, such as staff retention and company identification, rather than the vague assumption that it has been conforming to a legal obligation.

  8. ISOLDE PROGRAMME

    Fedosseev, V; Lynch, K M; Grob, L K; Herfurth, F; Scheidenberger, C; Geppert, C; Gorges, C; Ratajczyk, T; Vogel, S; Munch, M K; Nieminen, P; Pakarinen, J J A; Lecesne, N; Bouzomita, H; Grinyer, J; Marques moreno, F M; Parlog, M; Blank, B A; Pedroza, J; Ghetta, V; Guillemaud mueller, D S; Cottereau, E; Cheikh mhamed, M; Tusseau nenez, S; Tungate, G; Walker, P M; Smith, A G; Fitzpatrick, C; Dominik, W M; Karny, M; Ciemny, A A; Nyman, G H; Thies, R M A; Lindberg, S K G; Langouche, G F; Delaure, B J P; Mayet, P; Ory, G T; Kesteloot, N J K; Papuga, J; Dehairs, M H R; Callens, M; Domnanich, K A; Richter, D; Lutter, R J; Wiehr, S; Tengblad, O; Nacher gonzalez, E; Jungclaus, A; Ribeiro jimenez, G; Marroquin alonso, I; Cal gonzalez, J; Paziy, V; Salsac, M; Murphy, C; Podolyak, Z F; Bajoga, A D; Butler, P; Pritchard, A; Steer, A N; Fox, S P; Wadsworth, B A; Truesdale, V L; Al monthery, M; Hass, M; Guttormsen, M S; Badea, M N; Calinescu, S; Cederkall, J A; Zemlyanoy, S; Golovkov, M; Wu, C; Harrichunder, S; Ncube, M; Gerten, R F; Lehnert, J; Gladnishki, K A; Pospisil, S; Datta pramanik, U; Benzoni, G; Fedorov, D; Molkanov, P; Pfeiffer, B; Griesel, T; Wehner, L W; Mikkelsen, M; Recchia, F; Smith, J F; Kelly, C M; De melo bandeira tavares, P M; Vieira, J M; Martins da silva, M A; Lima lopes, A M; Mader, J; Kessler, P; Schweikhard, L C; Marx, G H; Kulczycka, E; Komorowska, M; Da silva, M F; Goncalves marques, C P; Baptista peres, M A; Welander, J E; Coeck, S; Ryssens, W A M; Knoops, G; Vanbuel, J; Reiter, P; Miller, C; Martin sanchez-cano, D; Wiens, A; Blazhev, A A; Braun, N; Cappellazzo, M V; Birkenbach, B; Gerst, R; Dannhoff, M F; Sithole, M J; Bilgier, B; Nardelli, S; Vetter, U; Araujo mendes, C M; Valencia marin, E; Pantea, E; Hessberger, F P; Leduc, A J; Mitsuoka, S; Carbonari, A W; Buchegger, F J; Garzon camacho, A; Stachura, M K; Stora, T; Marsh, B A; Thiboud, J A; Antalic, S; Stahl, C; Bauer, C; Thurauf, M; Maass, B; Sturm, S; Boehm, C; Wolf, N R; Ways, M; Riisager, K; Ruotsalainen, P A; Bastin, B; Duval, F T; Penessot, G; Flechard, X D; Desrues, P; Giovinazzo, J; Kurtukian nieto, T; Ascher, P E L; Roccia, S; Matea, I; Croizet, H A G; Bonnin, C M; Morfouace, P; Smith, A J; Guin, R; Banerjee, D; Ohtsubo, T; Zhukov, M V; Tengborn, E A; Dessagne, P; Juscamaita vivanco, Y; De rydt, M A E; Vermaelen, P; Monten, R; Yang, X; De coster, A; Kruecken, R; Muecher, D; Nowak, A K; Cano ott, D; Murphy, A S J; Shand, C M; Regan, P H; Jones, G D; Herzberg, R; Ikin, P; Davies, P J; Napoli, D R; Scarel, G; Larsen, A; Tornyi, T G; Pascu, S G; Stroe, L; Toma, S; Jansson, K; Dronjak fahlander, M; Krupko, S; Hurst, A M; Veskovic, M; Nikolov, J; Sibanda, W N; Rocchini, M; Deicher, M; Wichert, T; Wolf, E; Kronenberg, J; Helmke, A; Meliani, Z; Ivanov, V S; Kuti, I; Halasz, Z; Henry, M O; Bras de sequeira amaral, V; Espirito santo, F; Carvalho teixeira, R C; Rosendahl, S; Speidel, K; Agarwal, I; Faul, T; Kownacki, J M; Martins correia, J G; Lorenz, K; Costa miranda, S M; Granadeiro costa, A R; Keupers, M; Stukken, R; Wursten, E J; Kotthaus, T; Pfeiffer, M; Stegemann, S T; Gironi, L; Cakirli, R B; Jensen, A; Romstedt, F; Constantino silva furtado, I; Heredia cardona, J A; Jordan martin, M D; Montaner piza, A; Plewinski, F; Mesli, A; Pichard, A; Fallis starhunter, J P; Voulot, D; Mrazek, J; Ugryumov, V; Savreux, R P; Kojouharov, I M; Stegmann, R; Fitting, J; Lauer, M; Kirsebom, O S; Jensen, K L; Jokinen, A; Rahkila, P J; Hager, U D K; Dubois, M; Orr, N A; Fabian, X; Huikari, J E; Goigoux, T; Magron, C; Zakari, A A; Maietta, M; Bachelet, C E M; Roussiere, B; Li, R; Mertzimekis, T; Gislason, H P; Shayestehaminzadeh, S; Qi, B; Mukai, M; Watanabe, Y; Willmann, L; Kurcewicz, W; Wimmer, K; Meisel, Z P; Lievens, P; Neyens, G; Darby, I G; Descamps, B O; Bunka, M; Vermeulen, C; Podadera aliseda, I; Alcorta moreno, M; Pesudo fortes, V; Algora, A; Zielinska, M; Korten, W; Wang, C H; Lotay, G J; Mason, P; Rice, S J; Willenegger, L M; Judson, D S; Revill, J P; Andreev, A; Yavuzkanat, N; Kumar, V; Zamfir, N - V; Deleanu, D; Golubev, P I; Jeppesen, H B; Pain, S D; Stracener, D W; Matousek, V; Venhart, M; Birova, M; Li, X; Stuchbery, A E; Lellep, G M; Poves paredes, A; Chakraborty, S; Leoni, S; Chupp, T; Yilmaz, C; Severin, G; Garcia ramos, J E; Hadinia, B; Mc glynn, E; Monteiro de sena silvares de carvalho, I; Friedag, P; Koos, V; Meot, V H; Pauwels, D B; Jancso, A; Srebrny, J; Alves, E J; David bosne, E; Dexters, W M M; Velten, P; Kalkuehler, M; Albers, M; Bharuth-ram, K; Akkus, B; Hemmingsen, L B S; Pedersen, J T; Dos santos redondo, L M; Rubio barroso, B; Kozlov, V; Mokhles gerami, A; Bernardo da silva, E; Unzueta solozabal, I; Schell, J; Szybowicz, M; Lassen, J; Johnston, K; Miyazaki, A; Macko, M; Coquard, L; Bloch, T P; Bonig, E S; Ignatov, A

    2002-01-01

    The experiments aim at a broad exploration of the properties of atomic nuclei far away from the region of beta stability. Furthermore, the unique radioactive beams of over 60~elements produced at the on-line isotope separators ISOLDE-2 and ISOLDE-3 are used in a wide programme of atomic, solid state and surface physics. Around 300 scientists are involved in the project, coming from about 70 laboratories. \\\\ \\\\ The electromagnetic isotope separators are connected on-line with their production targets in the extracted 600 MeV proton or 910~MeV Helium-3 beam of the Synchro-Cyclotron. Secondary beams of radioactive isotopes are available at the facility in intensities of 10$^1

  9. ADS National Programmes: Italy

    Following a preliminary design developed in 1998, based on the Energy Amplifier concept proposed by CERN, a first configuration of a lead-bismuth Eutectic cooled Experimental ADS (LBE-XADS) was worked out in the period 1999–2001, under the aegis of MURST, by a group of Italian organizations led by Ansado Nucleare, with the aim of assessing the feasibility of a small sized (80 MWth) ADS. At the end of 1997 a joint effort of ENEA (National Agency for New Technology, Energy and the Environment) and INFN (National Institute for Nuclear Physics) led to the approval of a national programme by MURST (Minister for University and Scientific and Technological Research) named TRASCO (TRAsmutazione SCOrie) aiming at the study of physics and technologies needed to design an ADS for radioactive waste transmutation. The programme consisted of research subprogrammes on accelerator, neutronics, thermalhydraulics analysis, beam window technology, and material technology and compatibility with Pb and Pb-Bi. At now, most of the activities in support to the ADS development carried out at national level are part of EU-funded Projects. These activities are complemented by the programme agreement (AdP -Accordo di programma), signed between ENEA and the Ministry of Economic Development, which provides in general a range of activities aimed at the development of sustainable nuclear fission systems. Several universities and the national industry are involved, besides ENEA, in the activities

  10. Fusion technology programme

    KfK is involved in the European Fusion Programme predominantly in the NET and Fusion Technology part. The following fields of activity are covered: Studies for NET, alternative confinement concepts, and needs and issues of integral testing. Research on structural materials. Development of superconducting magnets. Gyrotron development (part of the Physics Programme). Nuclear technology (breeding materials, blanket design, tritium technology, safety and environmental aspects of fusion, remote maintenance). Reported here are status and results of work under contracts with the CEC within the NET and Technology Programme. The aim of the major part of this R and D work is the support of NET, some areas (e.g. materials, safety and environmental impact, blanket design) have a wider scope and address problems of a demonstration reactor. In the current working period, several new proposals have been elaborated to be implemented into the 85/89 Euratom Fusion Programme. New KfK contributions relate to materials research (dual beam and fast reactor irradiations, ferritic steels), to blanket engineering (MHD-effects) and to safety studies (e.g. magnet safety). (orig./GG)

  11. Instrumental neutron activation analysis as an analytical tool supporting the establishment of guidelines and databases for workers' health awareness programmes

    dangerous diseases that are easily identified. The main problem is that the majority of workers are exposed to low levels of toxic chemicals that can be lethal in the long term, owing to chronic diseases. Most often the onset of the diseases goes unnoticed, and the presence of a lung cancer or heart disease is attributed to non-occupational causes. As a result, these cases of illness do not become part of the compiled data. Besides, there is no specialized and complete literature concerning occupational aetiology, nor is there an evaluation of the onset of disease linked to long term exposure to low levels of toxic agents. With the aim of giving support to the Workers' Health Awareness Programme of the Secretaria Municipal de Saude (Municipal Department of Health) of Belo Horizonte, capital of Minas Gerais state, an assessment was done in galvanizing factories by means of airborne particulate matter collected in air filters and in hair and toenails as biomonitors. This project was approved by the Ethics Committee of the Federal University of Minas Gerais, COEP-UFMG. All research involving human beings has to be submitted to this committee in order to protect the population studied. The k0 instrumental neutron activation analysis (INAA) technique was chosen to be applied for the determination of elements in air filters and in hair and toenail samples, as it can determine several elements in the same sample almost simultaneously, with a low detection limit and without any chemical procedure as is required in the majority of non-nuclear techniques, and also because it requires only a small amount of sample for the analysis. The k0 method was applied to all samples, demonstrating its quality as a versatile technique, and it was confirmed to be one of the most advantageous and suitable nuclear analytical techniques

  12. Perspectives on kiss-and-run: role in exocytosis, endocytosis, and neurotransmission.

    Alabi, AbdulRasheed A; Tsien, Richard W

    2013-01-01

    Regulated exocytosis and endocytosis are critical to the function of many intercellular networks, particularly the complex neural circuits underlying mammalian behavior. Kiss-and-run (KR) is an unconventional fusion between secretory vesicles and a target membrane that releases intravesicular content through a transient, nanometer-sized fusion pore. The fusing vesicle retains its gross shape, precluding full integration into the planar membrane, and enough molecular components for rapid retrieval, reacidification, and reuse. KR makes judicious use of finite presynaptic resources, and mounting evidence suggests that it influences synaptic information transfer. Here we detail emerging perspectives on KR and its role in neurotransmission. We additionally formulate a restraining force hypothesis as a plausible mechanistic basis for KR and its physiological modulation in small nerve terminals. Clarification of the mechanism and function of KR has bearing on understanding the kinetic transitions underlying SNARE-mediated fusion, interactions between vesicles and their local environment, and the influence of release dynamics on neural information processing. PMID:23245563

  13. Dorsal spinous process impingement syndrome ('kissing spine') in a cat: imaging appearance and surgical management.

    Gutierrez-Quintana, Rodrigo; Lindley, Samantha; Sullivan, Martin; Penderis, Jacques; Wessmann, Annette

    2011-08-01

    Spinal pain is an important clinical presentation in feline patients, but the underlying causes can often be difficult to elucidate. Dorsal spinous process impingement syndrome ('kissing spine' or in human patients 'Baastrup syndrome') is a significant cause of spinal pain in equine and human patients and radiographically is characterised by a close approximation of adjacent spinous processes with reactive bone sclerosis affecting these spinous processes. In this report we describe the first reported case of dorsal spinous process impingement syndrome in a cat causing spinal pain, and successful surgical management of the syndrome. The affected cat presented at 5 years of age for evaluation of a 7-month history of progressive thoracolumbar pain. Radiographs revealed close approximation of the dorsal spinous processes of the seventh, eighth and ninth thoracic vertebrae (T7, T8 and T9), with associated reactive bone sclerosis. Surgical resection of the T8 dorsal spinous process resulted in complete resolution of the clinical signs with no evidence of recurrence 9 months after surgery. PMID:21723173

  14. Metal Abundances of KISS Galaxies. V. Nebular Abundances of Fifteen Intermediate Luminosity Star-Forming Galaxies

    Hirschauer, Alec S; Bresolin, Fabio; Saviane, Ivo; Yegorova, Irina

    2015-01-01

    We present high S/N spectroscopy of 15 emission-line galaxies (ELGs) cataloged in the KPNO International Spectroscopic Survey (KISS), selected for their possession of high equivalent width [O III] lines. The primary goal of this study was to attempt to derive direct-method ($T_e$) abundances for use in constraining the upper-metallicity branch of the $R_{23}$ relation. The spectra cover the full optical region from [O II]{\\lambda}{\\lambda}3726,3729 to [S III]{\\lambda}{\\lambda}9069,9531 and include the measurement of [O III]{\\lambda}4363 in 13 objects. From these spectra, we determine abundance ratios of helium, nitrogen, oxygen, neon, sulfur, and argon. We find these galaxies to predominantly possess oxygen abundances in the range of 8.0 $\\lesssim$ 12+log(O/H) $\\lesssim$ 8.3. We present a comparison of direct-method abundances with empirical SEL techniques, revealing several discrepancies. We also present a comparison of direct-method oxygen abundance calculations using electron temperatures determined from e...

  15. Programme budget 1981

    There are 11 main fields of KfK R + D activities which are connected with one or more of the research goals of a) assurance of nuclear fuel supply, b) nuclear waste management, c) safety of nuclear facilities, d) basic research and research on new technologies. The scientific and technical tasks connected with these goals in 1981 and on a medium-term basis as well as the financial requirements are presented in the programme budget. (orig.)

  16. Multilateral Interoperability Programme

    Burita, L.

    2009-01-01

    The Multilateral Interoperability Programme (MIP) is a voluntary and independent activity in NATO environment by the participating nations and organizations. The MIP concept is based on data exchange in form of common exchange data model to achieve the international interoperability in command and control information systems (C2IS) of the tactical units. The article describes the basis of the MIP organizations, structure, planning and testing processes. The core of the MIP solution is the Inf...

  17. Efficacy of Tailored Physical Activity or Chronic Pain Self-Management Programme on return to work for sick-listed citizens

    Andersen, Lotte Nygaard; Juul-Kristensen, Birgit; Sørensen, Thomas Lund;

    2015-01-01

    OBJECTIVES: The aim was to evaluate the efficacy of 'Tailored Physical Activity' (TPA) and a 'Chronic Pain Self-management Programme' (CPSMP) compared with a reference group (REF) on return to work after 3 months as sick-listed citizens with pain related to the back or the upper body. METHODS...... the municipality and the co-primary endpoint was duration of the sickness absence period. Secondary outcomes consisted of pain, body mass index, aerobic capacity, grip strength, work ability and kinesiophobia. The trial was conducted in Sonderborg Municipality from March 2011 to October 2013. RESULTS...

  18. The Back 2 Activity Trial: education and advice versus education and advice plus a structured walking programme for chronic low back pain

    Bradbury Ian

    2010-07-01

    Full Text Available Abstract Background Current evidence supports the use of exercise-based treatment for chronic low back pain that encourages the patient to assume an active role in their recovery. Walking has been shown it to be an acceptable type of exercise with a low risk of injury. However, it is not known whether structured physical activity programmes are any more effective than giving advice to remain active. Methods/Design The proposed study will test the feasibility of using a pedometer-driven walking programme, as an adjunct to a standard education and advice session in participants with chronic low back pain. Fifty adult participants will be recruited via a number of different sources. Baseline outcome measures including self reported function; objective physical activity levels; fear-avoidance beliefs and health-related quality of life will be recorded. Eligible participants will be randomly allocated under strict, double blind conditions to one of two treatments groups. Participants in group A will receive a single education and advice session with a physiotherapist based on the content of the 'Back Book'. Participants in group B will receive the same education and advice session. In addition, they will also receive a graded pedometer-driven walking programme prescribed by the physiotherapist. Follow up outcomes will be recorded by the same researcher, who will remain blinded to group allocation, at eight weeks and six months post randomisation. A qualitative exploration of participants' perception of walking will also be examined by use of focus groups at the end of the intervention. As a feasibility study, treatment effects will be represented by point estimates and confidence intervals. The assessment of participant satisfaction will be tabulated, as will adherence levels and any recorded difficulties or adverse events experienced by the participants or therapists. This information will be used to modify the planned interventions to be used in a

  19. What is the IAEA? Programmes and activities that maximize the contribution of nuclear technology to society, while verifying its peaceful use

    The International Atomic Energy Agency (IAEA) serves as the world's foremost international governmental forum for scientific and technical co-operation in the peaceful use of nuclear technology. Established as an autonomous organization under the United Nations (UN) in 1957, the IAEA represents the culmination of international efforts to make a reality of US President Eisenhower's proposal in his 'Atoms for Peace' speech to the UN General Assembly in 1953. He envisioned the creation of an international body to control and develop the use of atomic energy. Today, the Agency's broad spectrum of services, programmes, and activities is based on the needs of its 130 Member States

  20. ADS National Programmes: China

    In China the conceptual study of an ADS concept which lasted for about five years ended in 1999. As one project of the National Basic Research Programme of China (973 Programme) in energy domain, which is sponsored by the China Ministry of Science and Technology (MOST), a five year programme of fundamental research of ADS physics and related technology was launched in 2000 and passed national review at the end of 2005. From 2007, another five year 973 Programme Key Technology Research of Accelerator Driven Subcritical System for Nuclear waste Transmutation started. The research activities were focused on HPPA physics and technology, reactor physics of external source driven subcritical assembly, nuclear data base and material study. For HPPA, a high current injector consisting of an ECR ion source, LEBT and an RFQ accelerating structure of 3.5 MeV has been built and were being improved. In reactor physics study, a series of neutron multiplication experimental study has been carrying out. The VENUS I facility has been constructed as the basic experimental platform for neutronics study in ADS blanket. VENUS I a zero power subcritical neutron multiplying assembly driven by external neutron produced by a pulsed neutron generator or 252Cf neutron source. The theoretical, experimental and simulation studies on nuclear data, material properties and nuclear fuel circulation related to ADS are carried out in order to provide the database for ADS system analysis. China Institute of Atomic Energy (CIAE), Institute of High Energy Physics (IHEP) and other Chinese institutes carried out the MOST project together. Besides CIAE, China Academy of Science (CAS) pays more and more attention to Advanced Nuclear Fuel Cycles (ANFC). A large programme of ANFC, including ADS and Th based nuclear fuel cycle, has been launched by CAS

  1. Technical proposal for including health in the procedures for assessing the environmental impact of policies, plans, programmes, projects and activities

    Almudena García Nieto

    2015-05-01

    Full Text Available Health was an element of general licensing procedures until Spain joined the EU in 1986, when the health report became diluted. The purpose of this article is to provide an overview of this topic’s current regulatory framework and to try to briefly describe health priorities and the channels for feasibly integrating the health variable in the environmental assessment of plans, programmes and projects from the public and private sectors. The current existence of the Environmental Assessment Act and the Public Health Act may help to achieve this.When preparing a strategic environmental study and an environmental impact study, the health impact assessment should be considered an essential step in these environmental procedures and have the same legal treatment as the “compulsory and determinant reports” of said procedures.Thus, it is concluded that the regulatory development of the aspects relating to the assessment of the health impact of the plans, programmes and projects envisaged in the Environmental Assessment Act is essential, the health impact assessment being the tool for doing so.

  2. Nuclear waste management programme 1996

    Nuclear Waste Commission of Finnish Power Companies (YJT) founded by nuclear energy producing Imatran Voima Oy (IVO) and Teollisuuden Voima Oy (TVO), coordinates the research work of the companies on nuclear waste management. In YJT's Nuclear Waste Management Programme 1995, an account of the nuclear waste management measures of IVO and TVO is given as required by the sections 74 and 75 of the Finnish Nuclear Energy Degree. At first, the nuclear waste management situation and the programme of activities are reported. The nuclear waste management research programme for the year 1996 and more generally for the years 1997-2000 is presented. (1 fig., 1 tab.)

  3. Nuclear Waste Management Programme 1993

    Nuclear Waste Commission of Finnish Power Companies (YJT), founded by nuclear energy producing Imatran Voima Oy (IVO) and Teollisuuden Voima (TVO), coordinates the research work of the companies on nuclear waste management. In YJT's Nuclear Waste Management Programme 1993, an account of the nuclear waste management measures of IVO and TVO is given as required by the sections 74 and 75 of the Finnish Nuclear Energy Degree. At first, the nuclear waste management situation and the programme of activities are reported. Then the nuclear waste management research programme for the year 1993 and more generally for the years 1994-1997 is presented

  4. Nuclear waste management programme 1994

    Nuclear Waste Commission of Finnish Power Companies (YJT), founded by nuclear energy producing Imatran Voima Oy (IVO) and Teollisuuden Voima Oy (TVO), coordinates the research work of the companies on nuclear waste management. In YJT's Nuclear Waste Management Programme 1994, an account of the nuclear waste management measures of IVO and TVO is given as required by the sections 74 and 75 of the Finnish Nuclear Energy Degree. At first, the nuclear waste management situation and the programme of activities are reported. The the nuclear waste management research programme for the year 1994 and more generally for the years 1995-1997 is presented. (2 figs., 1 tab.)

  5. Nuclear Waste Management Programme 1992

    Nuclear Waste Commission of Finnish Power Companies (YJT), founded by nuclear energy producing Imatran Voima Oy (IVO) and Teollisuuden Voima Oy (TVO), coordinates the research work of the companies on nuclear waste management. In YJT's Nuclear Waste Management Programme 1992, an account of the nuclear waste management measures of IVO and TVO is given as required by the Sections 74 and 75 of the Finnish Nuclear Energy Degree. At first, the nuclear waste management situation and the programme of activities are reported. Then the nuclear waste management research programme for the year 1992 and more generally for the years 1993 - 1996 is presented. (author)

  6. A Statistical Programme Assignment Model

    Rosholm, Michael; Staghøj, Jonas; Svarer, Michael

    When treatment effects of active labour market programmes are heterogeneous in an observable way  across the population, the allocation of the unemployed into different programmes becomes a particularly  important issue. In this paper, we present a statistical model designed to improve the present...... duration of unemployment spells may result if a statistical programme assignment model is introduced. We discuss several issues regarding the  plementation of such a system, especially the interplay between the statistical model and  case workers....

  7. Experience from the Inspection of Licensees' Outage Activities, Including Fire Protection Programmes, Event Response Inspections, and the Impact of the Fukushima Daiichi NPP Accident on Inspection Programmes. Workshop Proceedings, Chattanooga, Tennessee, United States, 7-10 April 2014

    The main purpose of the workshop was to provide a forum of exchange of information on the regulatory inspection activities. Participants had the opportunity to meet with their counterparts from other countries and organisations to discuss current and future issues on the selected topics. They developed conclusions regarding these issues and hopefully, identified methods to help improve their own inspection programmes. The NEA Committee on Nuclear Regulatory Activities (CNRA) believes that an essential factor in ensuring the safety of nuclear installations is the continuing exchange and analysis of technical information and data. To facilitate this exchange the Committee has established working groups and groups of experts in specialised topics. The Working Group on Inspection Practices (WGIP) was formed in 1990 with the mandate '..to concentrate on the conduct of inspections and how the effectiveness of inspections could be evaluated..'. The WGIP facilitates the exchange of information and experience related to regulatory safety inspections between CNRA member countries. These proceedings cover the 12. International Workshop held by WGIP on regulatory inspection activities. This workshop, which is the twelfth in a series, along with many other activities performed by the Working Group, is directed towards this goal. The consensus from participants at previous workshops, noted that the value of meeting with people from other inspection organisations was one of the most important achievements. The focus of this workshop was on experience gained from regulatory inspection activities in three areas: - Inspection of Outage Activities Including Fire Protection Programmes. - Event Response Inspections. - The Impact of Inspection Programmes of the Fukushima Daiichi Nuclear Power Plant (NPP) Accident. The main objectives of the WGIP workshops are to enable inspectors to meet with inspectors from other organisations, to exchange information regarding regulatory inspection

  8. Bioergia Research Programme

    Asplund, D.

    1997-12-31

    The main objectives of Finland`s Bioenergia Research Programme are (1) To develop new methods of producing biofuels which can compete with imported fuels, demonstrating the most promising production methods through pilot schemes, (2) To develop and demonstrate 3 - 4 new pieces of equipment or methods connected with handling and using bioenergy, (3) To produce basic information on conversion techniques and evaluate the quality, usability and environmental impacts of the products as well as the overall economy of the entire production chain and to create 2-3 conversion methods for follow-up development by industry. The principle research areas are (1) Development of production technology for wood-derived fuels, (2) Peat production, (3) The use of bioenergy and (4) Biomass conversion. This conference paper discusses the results obtained so far and reviews in some detail the activities of the programme. 3 figs., 3 tabs.

  9. Bioergia Research Programme

    The main objectives of Finland's Bioenergia Research Programme are (1) To develop new methods of producing biofuels which can compete with imported fuels, demonstrating the most promising production methods through pilot schemes, (2) To develop and demonstrate 3 - 4 new pieces of equipment or methods connected with handling and using bioenergy, (3) To produce basic information on conversion techniques and evaluate the quality, usability and environmental impacts of the products as well as the overall economy of the entire production chain and to create 2-3 conversion methods for follow-up development by industry. The principle research areas are (1) Development of production technology for wood-derived fuels, (2) Peat production, (3) The use of bioenergy and (4) Biomass conversion. This conference paper discusses the results obtained so far and reviews in some detail the activities of the programme. 3 figs., 3 tabs

  10. NUMERICAL SIMULATION OF MOLTEN POOL AND CONTROL STRATEGY OF KISS POINT IN A TWIN-ROLL STRIP CASTING PROCESS

    2008-01-01

    Coupled turbulent flow, temperature fields of the twin-roll casting strip process were simulated by three-dimensional finite element method. Based on the heat balance calculation and using inverse methods between the simulations and real experiments,the relational models among casting speed, location, and coefficient of heat transfer between molten metal and rolls in different regions are given. In the simulation, the calculated surface temperatures are in good agreement with the measured values. An on-line model of kiss point is derived by simulations and the geometry of molten pool,corresponding control strategy is also proposed.

  11. The IAEA co-ordinated research programme on activation cross sections for the generation of long-lived radionuclides of importance in fusion reactor technology. Final report

    The present report summarizes the final results of the IAEA Co-ordinated Research Programme on ''Activation Cross Section for the Generator of Long-lived Radionuclides of Importance in Fusion Reactor Technology''. The goal of the CRP was to obtain reliable information (experimental and evaluated) for 16 long-lived activation reactions of special importance to fusion reactor technology. By limiting the scope of the CRP to just 16 reactions it was possible to establish a very effective focus to the joint effort of many laboratories that has led to the generation of a set of valuable new data which provide satisfactory answers to several questions of technological concern to fusion. (author). 11 refs, 5 tabs

  12. The (cost-effectiveness of an individually tailored long-term worksite health promotion programme on physical activity and nutrition: design of a pragmatic cluster randomised controlled trial

    Burdorf Alex

    2007-09-01

    Full Text Available Abstract Background Cardiovascular disease is the leading cause of disability and mortality in most Western countries. The prevalence of several risk factors, most notably low physical activity and poor nutrition, is very high. Therefore, lifestyle behaviour changes are of great importance. The worksite offers an efficient structure to reach large groups and to make use of a natural social network. This study investigates a worksite health promotion programme with individually tailored advice in physical activity and nutrition and individual counselling to increase compliance with lifestyle recommendations and sustainability of a healthy lifestyle. Methods/Design The study is a pragmatic cluster randomised controlled trial with the worksite as the unit of randomisation. All workers will receive a standard worksite health promotion program. Additionally, the intervention group will receive access to an individual Health Portal consisting of four critical features: a computer-tailored advice, a monitoring function, a personal coach, and opportunities to contact professionals at request. Participants are employees working for companies in the Netherlands, being literate enough to read and understand simple Internet-based messages in the Dutch language. A questionnaire to assess primary outcomes (compliance with national recommendations on physical activity and on fruit and vegetable intake will take place at baseline and after 12 and 24 months. This questionnaire also assesses secondary outcomes including fat intake, self-efficacy and self-perceived barriers on physical activity and fruit and vegetable intake. Other secondary outcomes, including a cardiovascular risk profile and physical fitness, will be measured at baseline and after 24 months. Apart from the effect evaluation, a process evaluation will be carried out to gain insight into participation and adherence to the worksite health promotion programme. A cost-effectiveness analysis and

  13. An environmental monitoring programme to assess and control the effects of liquid effluent discharges of low radio-activity to an inland lake

    The 400 MW(e) twin gas-cooled reactor power station at Trawsfynydd in North Wales is unique in the UK in that it uses water extracted from an inland lake, Lake Trawsfynydd, for cooling the turbine-generator steam condensers. The radio-active liquid effluent is discharged into this lake with the returning cooling water flow. The lake is 200m above sea level and is fed from mountain streams in an area of relatively high rainfall. The principal outflow of lake water is to a small hydroelectric power plant which discharges its water into the sea. Consumption of trout taken from this lake provides the critical radiological pathway for exposure to the public. The critical radionuclide is caesium-137 which is concentrated in the flesh of the fish. The monitoring programme used to assess the impact of the low-level liquid effluent discharges on the lake environment is described. This involves sampling water, bed sediments, flora and fauna, not only from the lake but also from the outfall stream. The methods of sampling, sample preparation and counting for assay of the radionuclides of interest are described. The results from this programme are described and they demonstrate that the lake bed provides a varying adsorption term in the balance equation for radionuclides discharged into this environment. Furthermore, it is found that the effects of these discharges are critically dependent on meteorological conditions and the management of the lake water volume. (author)

  14. Programmable hardware for reconfigurable computing systems

    Smith, Stephen

    1996-10-01

    In 1945 the work of J. von Neumann and H. Goldstein created the principal architecture for electronic computation that has now lasted fifty years. Nevertheless alternative architectures have been created that have computational capability, for special tasks, far beyond that feasible with von Neumann machines. The emergence of high capacity programmable logic devices has made the realization of these architectures practical. The original ENIAC and EDVAC machines were conceived to solve special mathematical problems that were far from today's concept of 'killer applications.' In a similar vein programmable hardware computation is being used today to solve unique mathematical problems. Our programmable hardware activity is focused on the research and development of novel computational systems based upon the reconfigurability of our programmable logic devices. We explore our programmable logic architectures and their implications for programmable hardware. One programmable hardware board implementation is detailed.

  15. Developing the necessary infrastructure. Chapter 1; IAEA activities in support of countries considering embarking on Nuclear Power Programme

    The IAEA supports in a variety of ways in establishing an appropriate infra-structure necessary to secure safe and reliable operation and still maintaining the international safeguards regime, especially in developing countries which are considering introduction of nuclear power programme. The TC projects to support introduction of nuclear power has been formulated and its number increased significantly recently. Various guidance documents have been published by the IAEA recently to enable progressive development of national infrastructure. The IAEA guidance documents constitute a basis of advises to newcomer countries. The recently formulated important mission is INIR mission to review the status of national infrastructure in the context of measuring the distance to the expected milestone. Finally, it is expected that the newcomers would make informed decision-making on going to nuclear power by fully understanding the necessary obligations and national long-term commitment, by confirming viability of nuclear power options in the country's energy plan through Energy Planning and long-term strategic assessment using IAEA guidance and tools

  16. An novel analog programmable power supply for active gain control of the Multi-Pixel Photon Counter (MPPC)

    Li, Zhengwei; Xu, Yupeng; Yan, Bo; Li, Yanguo; Lu, Xuefeng; Li, Xufang; Zhang, Shuo; Chang, Zhi; Li, Jicheng; Zhang, Yifei; Zhao, Jianling

    2016-01-01

    Silicon Photo-Multipliers (SiPM) are regarded as novel photo-detector to replace conventional Photo-Multiplier Tubes (PMTs). However, the breakdown voltage dependence on the ambient temperature results in a gain variation of $\\sim$3$\\% /^{\\circ} \\mathrm C$. This can severely limit the application of this device in experiments with wide range of operating temperature, especially in space telescope. An experimental setup in dark condition was established to investigate the temperature and bias voltage dependence of gain for the Multi-Pixel Photon Counter (MPPC), one type of the SiPM developed by Hamamatsu. The gain and breakdown voltage dependence on operating temperature of an MPPC can be approximated by a linear function, which is similar to the behavior of a zener diode. The measured temperature coefficient of the breakdown voltage is $(59.4 \\pm 0.4$ mV)$/^{\\circ} \\mathrm C$. According to this fact, a programmable power supply based on two zener diodes and an operational amplifier was designed with a positiv...

  17. Review of reactor physics activities relevant to FBR and ATR programmes in PNC, Japan, June 1977 to October 1978

    Reactor physics works in Power Reactor and Nuclear Fuel Development Corporation (PNC) are carried out in support of the FBR and ATR development programmes. The works are in progress with high efficiency, in cooperation of other related organizations in Japan and also overseas. The experimental fast reactor ''Joyo'' reached its full power of 50 MWt, being operated now to obtain technical data and experiences. The prototype fast breeder reactor ''Monju'' is nearing completion of its final design, and the surveys on its proposed site have been finished. The advanced thermal reactor ''Fugen'', a heavy water-moderated and boiling light water-cooled, reactor reached the criticality, and the power generation was successfully achieved. The data to be obtained are used for the development of a large demonstration reactor. After describing on these types of reactors briefly, the works on reactor physics are described as follows: for fast reactors, mockup experiment and analysis, evaluation of actinide nuclear data, development of core analytical method, and research on shielding; and for ATR, research with a deuterium critical assembly. (Mori, K.)

  18. Multilateral Interoperability Programme

    L. Burita

    2009-12-01

    Full Text Available The Multilateral Interoperability Programme (MIP is a voluntary and independent activity in NATO environment by the participating nations and organizations. The MIP concept is based on data exchange in form of common exchange data model to achieve the international interoperability in command and control information systems (C2IS of the tactical units. The article describes the basis of the MIP organizations, structure, planning and testing processes. The core of the MIP solution is the Information Exchange Data Model (IEDM. The Czech Armed Forces (CAF MIP process implementation is mentioned. The MIP example is a part of university education process.

  19. Proficiency tests in the determination of activity of radionuclides in radiopharmaceutical products measured by nuclear medicine services in 8 years of comparison programmes in Brazil.

    Tauhata, Luiz; Iwahara, Akira; de Oliveira, Antonio E; Rezende, Eduarda Alexandre; Delgado, José Ubiratan; da Silva, Carlos José; Dos Santos, Joyra A; Nícoli, Ieda G; Alabarse, Frederico G; Xavier, Ana Maria

    2008-01-01

    Proficiency tests were applied to assess the performance of 74 nuclear medicine services in activity measurements of (131)I, (123)I, (99)Tc(m), (67)Ga and (201)Tl. These tests produced 913 data sets from comparison programmes promoted by the National Laboratory for Ionizing Radiation Metrology (LNMRI) from 1999 to 2006. The data were evaluated against acceptance criteria for accuracy and precision and assigned as Acceptable or Not acceptable accordingly. In addition, three other statistical parameters were used as complementary information for performance evaluation which related to normative requirements and to radionuclide calibrators. The results have shown a necessity to improve quality control procedures and unsatisfactory performances of radionuclide calibrators, which incorporate Geiger-Müller detectors. PMID:18346902

  20. Proficiency tests in the determination of activity of radionuclides in radiopharmaceutical products measured by nuclear medicine services in 8 years of comparison programmes in Brazil

    Tauhata, Luiz [Laboratorio Nacional de Metrologia das Radiacoes Ionizantes, Instituto de Radioprotecao e Dosimetria, Comissao Nacional de Energia Nuclear, Rio de Janeiro (Brazil)], E-mail: tauhata@ird.gov.br; Iwahara, Akira; Oliveira, Antonio E. de [Laboratorio Nacional de Metrologia das Radiacoes Ionizantes, Instituto de Radioprotecao e Dosimetria, Comissao Nacional de Energia Nuclear, Rio de Janeiro (Brazil); Rezende, Eduarda Alexandre [Centro Federal de Educacao Tecnologica de Quimica de Nilopolis, Nilopolis (Brazil); Ubiratan Delgado, Jose; Silva, Carlos Jose da [Laboratorio Nacional de Metrologia das Radiacoes Ionizantes, Instituto de Radioprotecao e Dosimetria, Comissao Nacional de Energia Nuclear, Rio de Janeiro (Brazil); Santos, Joyra A. dos [CORAD, Comissao Nacional de Energia Nuclear, Rio de Janeiro (Brazil); Nicoli, Ieda G. [DIPLAN, Comissao Nacional de Energia Nuclear, Brasilia (Brazil); Alabarse, Frederico G.; Xavier, Ana Maria [ESPOA, Comissao Nacional de Energia Nuclear, Porto Alegre (Brazil)

    2008-06-15

    Proficiency tests were applied to assess the performance of 74 nuclear medicine services in activity measurements of {sup 131}I, {sup 123}I, {sup 99}Tc{sup m}, {sup 67}Ga and {sup 201}Tl. These tests produced 913 data sets from comparison programmes promoted by the National Laboratory for Ionizing Radiation Metrology (LNMRI) from 1999 to 2006. The data were evaluated against acceptance criteria for accuracy and precision and assigned as Acceptable or Not acceptable accordingly. In addition, three other statistical parameters were used as complementary information for performance evaluation which related to normative requirements and to radionuclide calibrators. The results have shown a necessity to improve quality control procedures and unsatisfactory performances of radionuclide calibrators, which incorporate Geiger-Mueller detectors.

  1. Proficiency tests in the determination of activity of radionuclides in radiopharmaceutical products measured by nuclear medicine services in 8 years of comparison programmes in Brazil

    Proficiency tests were applied to assess the performance of 74 nuclear medicine services in activity measurements of 131I, 123I, 99Tcm, 67Ga and 201Tl. These tests produced 913 data sets from comparison programmes promoted by the National Laboratory for Ionizing Radiation Metrology (LNMRI) from 1999 to 2006. The data were evaluated against acceptance criteria for accuracy and precision and assigned as Acceptable or Not acceptable accordingly. In addition, three other statistical parameters were used as complementary information for performance evaluation which related to normative requirements and to radionuclide calibrators. The results have shown a necessity to improve quality control procedures and unsatisfactory performances of radionuclide calibrators, which incorporate Geiger-Mueller detectors

  2. Las malqueridas: La chambre verte de F. Truffaut, Mes petites amoureuses de J. Eustache, Kiss me deadly de R. Aldrich y además Free Rider

    La madriguera

    2001-01-01

    La madriguera (2001). Las malqueridas: La chambre verte de F. Truffaut, Mes petites amoureuses de J. Eustache, Kiss me deadly de R. Aldrich y además Free Rider. Ediciones de intervención cultural S.L. http://hdl.handle.net/10251/41938. 58 58 36

  3. Self-reported care activities in a home-based intervention programme for families with multiple problems

    Tausendfreund, Tim; Metselaar, Janneke; Conradie, Jelte; de Groot, Maria Helena; Schipaanboord, Nicolien; Knot-Dickscheit, Jana; Grietens, Hans; Knorth, Erik J.

    2015-01-01

    The purpose of this paper is to describe the development and application of the KIPP-list of care activities. The acronym KIPP stands for Knowledge and Insight into Primary Processes. The instrument is intended as a tool for family coaches to systematically report care activities conducted in the Du

  4. Why some do but most don't. Barriers and enablers to engaging low-income groups in physical activity programmes: a mixed methods study

    Fox Kenneth R

    2011-06-01

    Full Text Available Abstract Background The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These chronic conditions are most pronounced in economically disadvantaged groups where physical activity levels are consistently lower, yet this group is particularly difficult to recruit and retain in physical activity programmes. This study examined the perceptions of participants, non-participants, and exercise leaders in a low-income area regarding barriers, motives, and enabling factors for organised physical activity with a view to improving recruitment and retention. Methods A mixed methods research approach was adopted to guide data collection and analysis. A survey, incorporating the Motivation for Physical Activity Measure - Revised (MPAM-R, was used to assess the motivations of 152 physical activity session participants in a highly deprived suburban neighbourhood. The MPAM-R data were analysed using t tests, analyses of variance to estimate age, body mass index, and activity mode differences and Pearson's correlation coefficient to address associations. Semi-structured interviews were also conducted with 33 local residents who did not participate in activity sessions and with 14 activity session leaders. All interviews were audio-taped, transcribed verbatim and analyzed using an inductive thematic approach. Results Participants reported cost, childcare, lack of time and low awareness as barriers to joining activity classes. The need for support, confidence and competence in order to take up activity was widely expressed, particularly among women. Once people are active, high levels of social interaction, interest and enjoyment are associated with improved levels of retention, with different types of physical activity scoring differently on these factors. Conclusions This study suggests that some factors such as cost, the fear of 'walking in alone', accessibility of facilities, and appropriate

  5. Can lay-led walking programmes increase physical activity in middle aged adults? A randomised controlled trial

    Lamb, S.; Bartlett, H; Ashley, A; W. Bird

    2002-01-01

    Design: Randomised controlled trial with one year follow up. Physical activity was measured by questionnaire. Other measures included attitudes to exercise, body mass index, cholesterol, aerobic capacity, and blood pressure.

  6. Positive affect as coercive strategy: conditionality, activation and the role of psychology in UK government workfare programmes

    Friedli, Lynne; Stearn, Robert

    2015-01-01

    Eligibility for social security benefits in many advanced economies is dependent on unemployed and underemployed people carrying out an expanding range of job search, training and work preparation activities, as well as mandatory unpaid labour (workfare). Increasingly, these activities include interventions intended to modify attitudes, beliefs and personality, notably through the imposition of positive affect. Labour on the self in order to achieve characteristics said to increase employabil...

  7. Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells.

    Suzuki, Junpei; Maruyama, Saho; Tamauchi, Hidekazu; Kuwahara, Makoto; Horiuchi, Mika; Mizuki, Masumi; Ochi, Mizuki; Sawasaki, Tatsuya; Zhu, Jinfang; Yasukawa, Masaki; Yamashita, Masakatsu

    2016-04-01

    A transcriptional repressor Gfi1 promotes T helper type 2 (Th2) cell development and inhibits Th17 and inducible regulatory T-cell differentiation. However, the role of Gfi1 in regulating Th1 cell differentiation and the Th1-type immune response remains to be investigated. We herein demonstrate that Gfi1 inhibits the induction of the Th1 programme in activated CD4 T cells. The activated Gfi1-deficient CD4 T cells spontaneously develop into Th1 cells in an interleukin-12- and interferon-γ-independent manner. The increase of Th1-type immune responses was confirmed in vivo in Gfi1-deficient mice using a murine model of nickel allergy and delayed-type hypersensitivity (DTH). The expression levels of Th1-related transcription factors were found to increase in Gfi1-deficient activated CD4 T cells. Tbx21, Eomes and Runx2 were identified as possible direct targets of Gfi1. Gfi1 binds to the Tbx21, Eomes and Runx2 gene loci and reduces the histone H3K4 methylation levels in part by modulating Lsd1 recruitment. Together, these findings demonstrate a novel regulatory role of Gfi1 in the regulation of the Th1-type immune response. PMID:26749286

  8. MDEP Conference on New Reactor Design Activities - Multinational Design Evaluation Programme (MDEP) Conference Proceedings, Paris, France, 10-11 September 2009

    The MDEP is a unique ten-nation initiative being undertaken by national regulatory authorities from Canada, China, Finland, France, Japan, Republic of Korea, the Russian Federation, South Africa, the United Kingdom, and the United States with the purposes of co-operating on safety design reviews of new reactors and identifying opportunities to harmonise and converge on safety licensing review practices and requirements. The OECD Nuclear Energy Agency has been chosen to provide the technical secretariat support. The International Atomic Energy Agency participates in many of the MDEP activities. Started in 2007 with co-operation on various pilot project issues, the MDEP's expected outcomes are: (1) improved effectiveness and efficiency of regulatory safety design reviews, (2) increased quality of safety assessments, and (3) and identified areas for the convergence of regulatory requirements and practices. Making each regulator stronger in its ability to make sovereign safety decisions is a key objective that cuts across all MDEP activities. In 2008, the top regulators from each national authority met as the MDEP Policy Group and adopted the present structure and programme of work for the MDEP, including the pursuit of co-operation on specific safety design reviews and pursuing closer co-ordination on harmonisation and convergence issues such as digital instrumentation and control, mechanical codes and standards, and vendor inspections. The MDEP is currently a long-term programme that focuses in near term and interim results to share within MDEP and with other stakeholders. With effective communications in mind, the MDEP Policy Group directed the NEA to co-ordinate the Conference on New Reactor Design Activities with the purpose of communicating to a wide spectrum of stakeholders worldwide as to the program of work and accomplishments of the MDEP, and soliciting feedback and input from these stakeholders regarding recommendations on how to co-operate more efficiently

  9. Olympic Partner Programme

    2008-01-01

    @@ The Olympic Partner Programme (TOP) is an international Olympic marketing programme created by the International Olympic Committee (IOC),which includes the Organising Committees of the Games,the National Olympic Committees and the TOP Partners.

  10. Co-ordination and methodological guidance of information activities in the Czechoslovak nuclear programme in building the branch information system

    The work of the control unit is described which secures the optimal operation of the system, its internal functions and its linkage with other systems. The aim of coordination and methodological activity is to strengthen working and organizational links within the framework of the construction and operation of sector information systems, the establishment of cooperation relations and the elimination of duplicity. (M.D.)

  11. Implementation of a metrology programme to provide traceability for radionuclides activity measurements in the CNEN Radiopharmaceuticals Producers Centers

    The commercialization and use of radiopharmaceuticals in Brazil are regulated by Agencia Nacional de Vigilancia Sanitaria (ANVISA) which require Good Manufacturing Practices (GMP) certification for Radiopharmaceuticals Producer Centers. Quality Assurance Program should implement the GMP standards to ensure radiopharmaceuticals have requirements quality to proving its efficiency. Several aspects should be controlled within the Quality Assurance Programs, and one of them is the traceability of the Radionuclides Activity Measurement in radiopharmaceuticals doses. The quality assurance of activity measurements is fundamental to maintain both the efficiency of the nuclear medicine procedures and patient and exposed occupationally individuals safety. The radiation doses received by patients, during the nuclear medicine procedures, is estimated according to administered radiopharmaceuticals quantity. Therefore it is very important either the activity measurements performed in radiopharmaceuticals producer centers (RPC) as the measurements performed in nuclear medicine services are traceable to national standards. This paper aims to present an implementation program to provide traceability to radionuclides activity measurements performed in the dose calibrators(well type ionization chambers) used in Radiopharmaceuticals Producer Center placed in different states in Brazil. The proposed program is based on the principles of GM Pand ISO 17025 standards. According to dose calibrator performance, the RPC will be able to provide consistent, safe and effective radioactivity measurement to the nuclear medicine services. (author)

  12. Active Agents of Health Promotion? The School's Role in Supporting the HPV Vaccination Programme

    Spratt, Jennifer; Shucksmith, Janet; Philip, Kate; McNaughton, Rebekah

    2013-01-01

    By providing a place in which children can be accessed, the school has long been a site for population-level health initiatives. Recent policy shifts towards health-promoting schools have however re-cast the school from passive host to active collaborator in public health. This paper examines secondary school teachers' views of their roles as…

  13. Implementation of a metrology programme to provide traceability for radionuclides activity measurements in the CNEN Radiopharmaceuticals Producers Centers

    Andrade, Erica A.L. de; Braghirolli, Ana M.S.; Tauhata, Luiz; Gomes, Regio S.; Silva, Carlos J., E-mail: erica@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Delgado, Jose U.; Oliveira, Antonio E.; Iwahara, Akira, E-mail: ealima@ird.gov.br [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2013-07-01

    The commercialization and use of radiopharmaceuticals in Brazil are regulated by Agencia Nacional de Vigilancia Sanitaria (ANVISA) which require Good Manufacturing Practices (GMP) certification for Radiopharmaceuticals Producer Centers. Quality Assurance Program should implement the GMP standards to ensure radiopharmaceuticals have requirements quality to proving its efficiency. Several aspects should be controlled within the Quality Assurance Programs, and one of them is the traceability of the Radionuclides Activity Measurement in radiopharmaceuticals doses. The quality assurance of activity measurements is fundamental to maintain both the efficiency of the nuclear medicine procedures and patient and exposed occupationally individuals safety. The radiation doses received by patients, during the nuclear medicine procedures, is estimated according to administered radiopharmaceuticals quantity. Therefore it is very important either the activity measurements performed in radiopharmaceuticals producer centers (RPC) as the measurements performed in nuclear medicine services are traceable to national standards. This paper aims to present an implementation program to provide traceability to radionuclides activity measurements performed in the dose calibrators(well type ionization chambers) used in Radiopharmaceuticals Producer Center placed in different states in Brazil. The proposed program is based on the principles of GM Pand ISO 17025 standards. According to dose calibrator performance, the RPC will be able to provide consistent, safe and effective radioactivity measurement to the nuclear medicine services. (author)

  14. Randomized comparison of final kissing balloon dilatation versus no final kissing balloon dilatation in patients with coronary bifurcation lesions treated with main vessel stenting: the Nordic-Baltic Bifurcation Study III

    Niemelä, Matti; Kervinen, Kari; Erglis, Andrejs;

    2011-01-01

    BACKGROUND: It is unknown whether the preferred 1-stent bifurcation stenting approach with stenting of the main vessel (MV) and optional side branch stenting using drug-eluting stents should be finalized by a kissing balloon dilatation (FKBD). Therefore, we compared strategies of MV stenting with...... twenty-six patients had a quantitative coronary assessment. At 8 months, the rate of binary (re)stenosis in the entire bifurcation lesion (MV and side branch) was 11.0% versus 17.3% (P=0.11), in the MV was 3.1% versus 2.5% (P=0.68), and in the side branch was 7.9% versus 15.4% (P=0.039) in the FKBD...

  15. The Winfrith DSN programme

    The programme, which is written in the Fortran language, solves the Carlson discrete Sn approximation to the Boltzmann transport equation in cylindrical geometry. This report describes the input and output facilities of the WINFRITH DSN programme and the associated editing programme WED. (author)

  16. A reappraisal of the virtues of private sector employment programmes

    Graversen, Brian Krogh; Jensen, Peter

    2010-01-01

    This paper evaluates the employment effects of active labour market programmes for Danish welfare benefit recipients, focusing on private sector employment (PSE) programmes. Using a latent variable model that allows for heterogeneous treatment effects among observationally identical persons, we...

  17. Factors affecting 210Po and 210Pb activity concentrations in mussels and implications for environmental bio-monitoring programmes

    The activity of 210Po and 210Pb was determined in mussels of the same size (3.5-4.0 cm shell length) sampled monthly over a 17-month period at the Atlantic coast of Portugal. Average radionuclide concentration values in mussels were 759 ± 277 Bq kg-1 for 210Po (range 460-1470 Bq kg-1 dry weight), and 45 ± 19 Bq kg-1 for 210Pb (range 23-96 Bq kg-1 dry weight). Environmental parameters and mussel biometric parameters were monitored during the same period. Although there was no seasonal variation of radionuclide concentrations in sea water during the study period, the concentration of radionuclide activity in mussels varied seasonally displaying peaks of high concentrations in winter and low concentrations in summer. Analysis of radionuclide data in relation to the physiological Condition Index of mussels revealed that 210Po and 210Pb activities in the mussel (average activity per individual) remained nearly constant during the investigation period, while mussel body weight fluctuated due to fat storage/expenditure in the soft tissues. Similar variation of radionuclide concentrations was observed in mussels transplanted from the sea coast into the Tejo Estuary. However, under estuarine environmental conditions and with higher food availability throughout the year, transplanted mussel Condition Index was higher than in coastal mussels and average radionuclide concentrations were 210 ± 75 Bq kg-1 (dry weight) for 210Po and 10 ± 4 Bq kg-1 (dry weight) for 210Pb, therefore lower than in coastal mussels with similar shell length. It is concluded that the apparent seasonal fluctuation and inter-site difference of radionuclide concentrations were mostly caused by mussel body weight fluctuation and not by radionuclide body burden fluctuation. This interpretation can be extended to the apparent seasonal fluctuation in concentrations of lipophilic and lipophobic contaminants in mussels, and provides an explanation for occasional high concentrations of 210Po and man

  18. VTT Energy launches new ALWR programme

    VTT Energy and other Finnish organisations have carried out development activities on various advanced light water reactors (ALWRs) for some time. To broaden cooperation between different partners and make participation in international research programmes in this field easier, VTT Energy launched a four-year ALWR research programme in January 1998

  19. ADS National Programmes: Belgium

    The Belgian activities in the field of Accelerator Driven Systems (ADS) are mainly related to the MYRRHA project development. MYRRHA is an accelerator driven, multi purpose fast neutron spectrum facility for R&D, cooled by a lead-bismuth eutectic. SCK•CEN has started the MYRRHA project as a national programme with several national & international bilateral collaboration agreements; the project has now evolved as an European integrated project in the frame of the IPEUROTRANS (European Commission, Sixth Framework Programme). The MYRRHA ‘Draft-2’ predesign file (completed in the early 2005) has been proposed to the partners as a basis for the XT-ADS machine. After a detailed investigation of potential alternatives, the MYRRHA concept (for the subcritical core, the primary coolant system, the accommodation of experimental rigs, the reactor vessel and the spallation target) has been kept with some modifications to achieve the XT-ADS objectives. The most recent version of the XT-ADS design was presented in the 2007 TWG meeting

  20. The Possibility of Social Change and Pop Music in Serbia: Šobaja’s Three Kisses – A Case Study

    Aleksandar Brkić

    2016-02-01

    Full Text Available Can social change be brought about only in a radical manner? Is a radical manner of bringing about change possible at all? When we say social change, do we mean "revolution"? Is there a different way of looking at social change, and what is the role of elite culture and that of popular culture in these processes? Has the temporally and contextually limited effect of change and guerilla subversion through popular culture proved more effective? This small-scale study aims to raise the question of whether pop music can contribute to positive changes in society, and examines the conditions for this possibility through the case study of Nebojša "Šobaja" Anđelković’s song Three Kisses, declared the biggest music hit of 2009 in Serbia.

  1. Expert validation of fit-for-purpose guidelines for designing programmes of assessment.

    Dijkstra, J.; Galbraith, R.; Hodges, B.D.; McAvoy, P.A.; McCrorie, P.; Southgate, L.J.; Vleuten, C.P.M. van der; Wass, V.; Schuwirth, L.W.

    2012-01-01

    ABSTRACT: BACKGROUND: An assessment programme, a purposeful mix of assessment activities, is necessary to achieve a complete picture of assessee competence. High quality assessment programmes exist, however, design requirements for such programmes are still unclear. We developed guidelines for desig

  2. Positive affect as coercive strategy: conditionality, activation and the role of psychology in UK government workfare programmes.

    Friedli, Lynne; Stearn, Robert

    2015-06-01

    Eligibility for social security benefits in many advanced economies is dependent on unemployed and underemployed people carrying out an expanding range of job search, training and work preparation activities, as well as mandatory unpaid labour (workfare). Increasingly, these activities include interventions intended to modify attitudes, beliefs and personality, notably through the imposition of positive affect. Labour on the self in order to achieve characteristics said to increase employability is now widely promoted. This work and the discourse on it are central to the experience of many claimants and contribute to the view that unemployment is evidence of both personal failure and psychological deficit. The use of psychology in the delivery of workfare functions to erase the experience and effects of social and economic inequalities, to construct a psychological ideal that links unemployment to psychological deficit, and so to authorise the extension of state-and state-contracted-surveillance to psychological characteristics. This paper describes the coercive and punitive nature of many psycho-policy interventions and considers the implications of psycho-policy for the disadvantaged and excluded populations who are its primary targets. We draw on personal testimonies of people experiencing workfare, policy analysis and social media records of campaigns opposed to workfare in order to explore the extent of psycho-compulsion in workfare. This is an area that has received little attention in the academic literature but that raises issues of ethics and professional accountability and challenges the field of medical humanities to reflect more critically on its relationship to psychology. PMID:26052120

  3. Education, Training and the Euratom Framework Programme

    The maintaining of knowledge implies education and training programmes that ensure not only the instruction of students and trainees but also the transfer of knowledge across generations. This is especially important for research in the Euratom field in the present context of nuclear renaissance. DG-Research is responsible for the implementation of the Euratom Framework Programme on nuclear research and training. Through these activities, it is striving to promote the integration of national radiation protection research programmes in Europe, including education and training in radiation protection. These education and training activities supported in the Euratom Programme are helping to establish top-quality teaching modules assembled into masters programmes or higher-level training packages jointly qualified and mutually recognised across the EU. This Euratom approach is entirely in line with the Bologna process. This paper presents and discusses the various actions in education and training in radiation protection supported by DG- Research. (authors)

  4. Evaluating an in-home multicomponent cognitive behavioural programme to manage concerns about falls and associated activity avoidance in frail community-dwelling older people: Design of a randomised control trial [NCT01358032

    van Rossum Erik

    2011-09-01

    Full Text Available Abstract Background Concerns about falls are frequently reported by older people. These concerns can have serious consequences such as an increased risk of falls and the subsequent avoidance of activities. Previous studies have shown the effectiveness of a multicomponent group programme to reduce concerns about falls. However, owing to health problems older people may not be able to attend a group programme. Therefore, we adapted the group approach to an individual in-home programme. Methods/Design A two-group randomised controlled trial has been developed to evaluate the in-home multicomponent cognitive behavioural programme to manage concerns about falls and associated activity avoidance in frail older people living in the community. Persons were eligible for study if they were 70 years of age or over, perceived their general health as fair or poor, had at least some concerns about falls and associated avoidance of activity. After screening for eligibility in a random sample of older people, eligible persons received a baseline assessment and were subsequently allocated to the intervention or control group. Persons assigned to the intervention group were invited to participate in the programme, while those assigned to the control group received care as usual. The programme consists of seven sessions, comprising three home visits and four telephone contacts. The sessions are aimed at instilling adaptive and realistic views about falls, as well as increasing activity and safe behaviour. An effect evaluation, a process evaluation and an economic evaluation are conducted. Follow-up measurements for the effect evaluation are carried out 5 and 12 months after the baseline measurement. The primary outcomes of the effect evaluation are concerns about falls and avoidance of activity as a result of these concerns. Other outcomes are disability and falls. The process evaluation measures: the population characteristics reached; protocol adherence by

  5. Photovoltaic programme - edition 2003

    NONE

    2003-07-01

    This publication issued by the Swiss Federal Office of Energy's Photovoltaics (PV) Programme presents an overview (in English) of activities and projects in the photovoltaics research and pilot and demonstration area in Switzerland. Progress in the area of future solar cell technologies, modules and building integration, system technologies, planning and operating aids is summarised. Also, PV for applications in developing countries, thermo-photovoltaics and international co-operation are commented on. In the area of pilot and demonstration projects, component development, PV integration in sloping roofs, on flat roofs and noise barriers as well as further PV plant are looked at. Also, measurement campaigns, studies, statistics and further PV-related topics are summarised. This volume also presents the abstracts of reports made by the project managers of 73 research and pilot and demonstration projects in these areas for 2002.

  6. INDUSTRIAL RISK Programme development

    INC-DTCI ICIS Rm. Valcea conducts basic and applied research among which there is the INDUSTRIAL RISK Programme that comprises studies of risk analysis and evaluation at objectives and activities in zones were risk factors are in operation, factors leading potentially to natural or technological disasters. The risk analysis and evaluation methodology proposed is a follow-up of the action plan for risk reduction in industry. The risk management refers to risk and its components assessment and identification of places where improvements are to be introduced. The risk analysis and evaluation model was developed for installations in chemical industry and are also applicable for the installations of heavy water production by H2O-H2S isotopic exchange. The risk studies supply information necessary in making decisions, aiming at preventing the operation incidence and reducing their consequences

  7. A Randomised Control Trial of the Impact of a Computer-Based Activity Programme upon the Fitness of Children with Autism

    Kathleen Dickinson

    2014-01-01

    Full Text Available The poor levels of fitness in children with autism are prompting concern for the children’s future health. This study looked to assess if a computer-based activity programme could improve fitness levels (as reflected in cardiopulmonary function of these children, and achieve a reduction in their body mass index. In a randomised controlled trial, 50 children with autism (of which 33 were under the age of 11 years and 39 were boys were allocated to an intervention group which encouraged them to use the Nintendo Wii and the software package “Mario and Sonics at the Olympics” in addition to their routine physical education classes. 50 children with autism (34 under the age of 11 years and 40 being boys acted as controls. At the end of one year, analysis of the changes in scores using analysis of covariance (ANCOVA on the Eurofit fitness tests showed that the intervention group had made statistically significant improvement on all tests other than flexibility. These improvements were also significantly better than controls. This type of intervention appears to be an effective addition to standard fitness training in order to help children with autism improve their fitness levels.

  8. Effect of an education and activation programme on functional limitations and patient-perceived recovery in acute and sub-acute shoulder complaints – a randomised clinical trial

    Goossens Marielle

    2007-11-01

    Full Text Available Abstract Background The education and activation programme (EAP aims at coping with psychosocial determinants to prevent the development of chronic shoulder complaints (SCs. The effect of the EAP on functional limitations and patient-perceived recovery after 6 and 26 weeks is evaluated in a randomised clinical trial. Methods Patients with SCs present at rest or elicited by movement and lasting no longer than 3 months were allocated at random to either EAP as an addition to usual care (UC, or to UC only. Measurements were taken at baseline and after 6 and 26 weeks and were analysed by means of multilevel analysis for the group effect. EAP was administered by GPs or by an ambulant therapist (CDB. Patients in the UC group were given UC by their own GP. Results Multilevel analysis failed to show a significant effect of the EAP on either functional limitations or patient-perceived recovery. Analysis showed coincidentally a relation between catastrophising at baseline and functional limitations. Conclusion The EAP has no significant effect on the outcome of SCs after 6 and 26 weeks. The relation between catastrophising at baseline and functional limitations suggests that an intervention focusing specifically on catastrophising may be more successful in reducing functional limitations in the long term. Further research is however needed to evaluate the effect of catastrophising at baseline on the course of SCs. Trial registration Current Controlled Trials ISRCTN71777817

  9. Act No 85 of 18 March 1982 granting the Comitato Nazionale per l'Energia Nucleare a State contribution of 2,890 milliard lire to the 5-year activity programme 1980-1984

    This Act came into force on 23 March 1982. It provides for the financing of the ENEA's (formerly CNEN) programme of work for the period 1980-1984. It further provides that within one year of its entry into force, the Directorate for Nuclear Safety and Health Protection - DISP (formerly within CNEN) will be set up as an independent, autonomous body, with tasks involving control over activities entailing major risks, including nuclear activities. (NEA)

  10. Aminoglycoside binding to the HIV-1 RNA dimerization initiation site: thermodynamics and effect on the kissing-loop to duplex conversion

    Bernacchi, Serena; Freisz, Séverine; Maechling, Clarisse; Spiess, Bernard; Marquet, Roland; Dumas, Philippe; Ennifar, Eric

    2007-01-01

    Owing to a striking, and most likely fortuitous, structural and sequence similarity with the bacterial 16 S ribosomal A site, the RNA kissing-loop complex formed by the HIV-1 genomic RNA dimerization initiation site (DIS) specifically binds 4,5-disubstituted 2-deoxystreptamine (2-DOS) aminoglycoside antibiotics. We used chemical probing, molecular modeling, isothermal titration calorimetry (ITC) and UV melting to investigate aminoglycoside binding to the DIS loop–loop complex. We showed that ...

  11. En Note om Programmering

    Nørmark, Kurt

    2012-01-01

    Denne note er en introduktion til programmering. Formålet er at give dig et indblik i hvad programmering egentlig er for noget. Jeg vil vise at programmering kan foregå på forskellige måder, og at der er mange forskellige udfordringer forbundet med at programmere. Noten vil ikke knytte sig til et...... bestemt programmeringssprog. Noten vil kunne supplere et egentlig undervisningsmateriale, der støtter dig i en bestemt form for programmering i et udvalgt programmeringssprog....

  12. Cold exposure inhibits hypothalamic Kiss-1 gene expression, serum leptin concentration, and delays reproductive development in male Brandt's vole ( Lasiopodomys brandtii)

    Zhang, Qiang; Lin, Yi; Zhang, Xue-Ying; Wang, De-Hua

    2015-06-01

    Cold commonly affects growth and reproductive development in small mammals. Here, we test the hypothesis that low ambient temperature will affect growth and puberty onset, associated with altered hypothalamic Kiss-1 gene expression and serum leptin concentration in wild rodents. Male Brandt's voles ( Lasiopodomys brandtii) were exposed to cold (4 ± 1 °C) and warm (23 ± 1 °C) conditions from the birth and sacrificed on different developmental stages (day 26, day 40, day 60, and day 90, respectively). Brandt's voles increased the thermogenic capacity of brown adipose tissue, mobilized body fat, decreased serum leptin levels, and delayed the reproductive development especially on day 40 in the cold condition. They increased food intake to compensate for the high energy demands in the cold. The hypothalamic Kiss-1 gene expression on day 26 was decreased, associated with lower wet testis mass and testis testosterone concentration on day 40, in the cold-exposed voles compared to that in the warm. Serum leptin was positively correlated with body fat, testis mass, and testosterone concentration. These data suggested that cold exposure inhibited hypothalamic Kiss-1 gene expression during the early stage of development, decreased serum leptin concentration, and delayed reproductive development in male Brandt's voles.

  13. Position of the kissing-loop interaction associated with PTE-type 3’CITEs can affect enhancement of cap-independent translation

    Chattopadhyay, Maitreyi; Kuhlmann, Micki M.; Kumar, Kalyani; Simon, Anne E.

    2014-01-01

    The Panicum mosaic virus-like translation enhancer (PTE) functions as a cap-independent translation enhancer (3’CITE) in members of several Tombusviridae genera including 7/19 carmoviruses. For nearly all PTE, a kissing-loop connects the element with a hairpin found in several conserved locations in the genomic RNA (5’ terminal hairpin or ~100 nt from the 5’end) and small subgenomic RNA (~63 nt from the 5’end). Moving the interaction closer to the 5’end in reporter mRNAs using Saguaro cactus virus (SCV) sequences had either a minimal or substantial negative effect on translation. Movement of the kissing loop from position 104 to the SCV 5’ terminal hairpin also reduced translation by 4-fold. These results suggest that relocating the PTE kissing loop closer to the 5’end reduces PTE efficiency, in contrast to results for the Barley yellow dwarf BTE and Tomato bushy stunt virus Y-shaped 3’CITEs , suggesting that different 3’CITEs have different bridging requirements. PMID:24928038

  14. Patient Experiences of Structured Heart Failure Programmes

    Nuala E. Tully

    2010-01-01

    Full Text Available Objectives. Patient experiences of structured heart failure rehabilitation and their views on the important components of heart failure services were examined. Methods. Focus groups were conducted with fifteen participants (men, =12 attending one of two heart failure rehabilitation programmes. Sessions were guided by a semistructured interview schedule covering participants' experiences of the programme, maintenance, and GP role. Focus group transcripts were analysed qualitatively. Results. Participants indicated that rehabilitation programmes substantially met their needs. Supervised exercise sessions increased confidence to resume physical activity, while peer-group interaction and supportive medical staff improved morale. However, once the programme ended, some participants' self-care motivation lapsed, especially maintenance of an exercise routine. Patients doubted their GPs' ability to help them manage their condition. Conclusion. Structured rehabilitation programmes are effective in enabling patients to develop lifestyle skills to live with heart failure. However, postrehabilitation maintenance interventions are necessary to sustain patients' confidence in disease self-management.

  15. ADS National Programmes: Japan

    In Japan, the research and development (R&D) activities on partitioning and transmutation (P&T) technology had been promoted under the OMEGA programme since 1988. The main institutes involved in these activities were the Japan Atomic Energy Research Institute (JAERI), the Japan Nuclear Cycle Development Institute (JNC), and the Central Research Institute of Electric Power Industry (CRIEPI). Among these institutes, JAERI had mainly conducted the R&D on ADS. In 1999 and 2000, the Atomic Energy Commission (AEC) of Japan implemented the check and review (C&R) on the P&T technology, and the ADS was considered as one of candidates for transmutation systems together with fast reactors. In 2005, JAERI and JNC were merged and the Japan Atomic Energy Agency (JAEA) was established. In JAEA, the R&D activities on both ADS and fast reactors have been continued. In August, 2008, the AEC of Japan launched the Technical Subcommittee on P&T Technology under the Advisory Committee on R&D, and conducted the discussion about the current state of the art concerning P&T technology in Japan and the future R&D programme. The Subcommittee issued the final report in April, 2009. The final report covered the impact of the P&T technology, the state of the art of the technology, evaluation on the progress of the R&D, and the recommendations of the future R&D. As the basic policy on the P&T technology, the report stated that the R&D should not aim at only the improvement of the P&T performance, but at the achievement of the requirements for whole performance of nuclear power generation. This means that the performance of the Double strata fuel cycle concept should be evaluated from viewpoints of safety, economy, environmental friendliness, saving resource, and non-proliferation of the first stratum as well as those of the second stratum. The Double strata concept, therefore, should be studied as a part of the whole nuclear system both in the transient phase of LWR to FBR and the equilibrium

  16. Swiss breeder research programme

    A new initiative for a Swiss Fast Breeder Research Program has been started during 1991. This was partly the consequence of a vote in Fall 1990, when the Swiss public voted for maintaining nuclear reactors in operation, but also for a moratorium of 10 years, within which period no new reactor project should be proposed. On the other hand the Swiss government decided to keep the option 'atomic reactors' open and therefore it was essential to have programmes which guaranteed that the knowledge of reactor technology could be maintained in the industry and the relevant research organisations. There is also motivation to support a Swiss Breeder Research Program on the part of the utilities, the licensing authorities and the Paul Scherrer Institute (PSI). The utilities recognise the breeder reactor as an advanced reactor system which has to be developed further and might be a candidate, somewhere in the future, for electricity production. In so far they have great interest that a know-how base is maintained in our country, with easy access for technical questions and close attention to the development of this reactor type. The licensing authorities have a legitimate interest that an adequate knowledge of the breeder reactor type and its functions is kept at their disposal. PSI and the former EIR have had for many years a very successful basic research programme concerning breeder reactors, and were in close cooperation with EFR. The activities within this programme had to be terminated owing to limitations in personnel and financial resources. The new PSI research programme is based upon two main areas, reactor physics and reactor thermal hydraulics. In both areas relatively small but valuable basic research tasks, the results of which are of interest to the breeder community, will be carried out. The lack of support of the former Breeder Programme led to capacity problems and finally to a total termination. Therefore one of the problems which had to be solved first was

  17. SET-Routes programme

    CERN audiovisual service

    2009-01-01

    The SET-Routes programme, launched in 2007 with the goal of attracting girls and young women to careers in science, came to an end in April this year. The result of a collaboration between EMBL, EMBO and CERN, the programme established a network of "ambassadors", women scientists who went out to talk about their careers in science at schools and universities across Europe.

  18. Fusion technology programme

    KfK participates to the Fusion Technology Programme of the European Community. Most of the work in progress addresses the Next European Torus (NET) and the long term technology aspects as defined in the 82/86 programme. A minor part serves to preparation of future contributions and to design studies on fusion concepts in a wider perspective. The Fusion Technology Programme of Euratom covers mainly aspects of nuclear engineering. Plasma engineering, heating, refueling and vacuum technology are at present part of the Physics Programme. In view of NET, integration of the different areas of work will be mandatory. KfK is therefore prepared to address technical aspects beyond the actual scope of the physics experiments. The technology tasks are reported project wise under title and code of the Euratom programme. Most of the projects described here are shared with other European fusion laboratories as indicated in the table annexed to this report. (orig./GG)

  19. Auditing as method of QA programme evaluation

    The status and adequacy of a quality assurance programme should be regularly reviewed by the cognizant management. The programme audit is an independent review to determine the compliance with respective quality assurance requirements and to determine the effectiveness of that programme. This lecture gives an introduction of the method to perform audits under the following topics: 1. Definition and purpose of quality audits. 2. Organization of the quality audit function. 3. Unique requirements for auditors. 4. Audit preparation and planning. 5. Conduct of the audit. 6. Reporting the audit results. 7. Follow-up activities. (RW)

  20. Country programme review Republic of Cameroon

    A multi-disciplinary country programme review and programming mission was undertaken to the Republic of Cameroon, from 21 to 25 June 1993. This report reflects the findings and recommendations of the mission and falls into four sections. The first section describes the country profile and includes information about its economy and its development plans and policies. The second reviews the Agency's past and present technical co-operation programmes in Cameroon. The third section deals with a sectoral programme and institutional review, and the fourth section presents possible future technical co-operation activities

  1. Observation of a Change in Bend of an RNA Kissing Complex Using the Angular Dependence of Fluorescence Resonance Energy Transfer

    Rahmanseresht, Sheema; Gamari, Ben D; Goldner, Lori S

    2014-01-01

    We report on the observation of a change in the bend angle of an RNA kissing complex upon Rop binding using single-molecular-pair FRET. The angular relationship between the dyes, rather than the distance between them, is shown to be responsible for the observed change in energy transfer. It has long been thought that Rop increases the bend angle of the R1inv-R2inv complex upon binding, but this has never been directly observed. In contrast, we find an increase in FRET upon the addition of Rop that is shown via modeling to be consistent with a decrease in the bend angle of the complex of $-15^{\\circ}\\pm7^{\\circ}$. The model predicts FRET from dye trajectories generated using molecular dynamics simulations of Cy3 and Cy5 attached to $5'$ terminal cytosine or guanosine on RNA. While FRET is commonly used to observe global changes in molecular structure attributed to changes in the distance between dyes, it is rarely, if ever, used to elucidate angular changes. Subtle global changes in molecular structure upon bi...

  2. [Health Communication: Preventing the Spread of Ebola Virus Disease in the Portuguese Spoken African Countries--Methodology KISS & KEYWORDS].

    Santiago, Isabel De; Miguel, José Pereira; Antunes, Francisco

    2015-01-01

    In this work, Health Communication is considered as an important discipline in medicine and health sciences for his role as true determinant of health. We highlight their contribution to health promotion and disease prevention. Thus, the Health Communication Plan (PCS): Preventing the spread of Ebola virus disease in the Portuguese Speaking African Countries - KISS & KEYWORDS methodology is a tool that aims to minimize the risk of infection by Ebola virus in the Portuguese Speaking African Countries and also train for a general improvement of health conditions of the local populations. In the PCS design are especially considered the social and cultural contexts of the target populations, especially the customs, traditions and religion. Health Communication is considered as an Essential Function of Public Health and its main is to provide a population-based approach. The target of communication actions are population groups in addition to the individual communication, target-audiences are people without access to the media, in Guinea Bissau, Cape Verde and Sao Tome and Principe. Under the communication plan uses the methodology, models and practices both by media professionals as health. A proximity approach and cultural mediation, previously identified key facts, are defined objectives; outlines to the Plan in concrete and its implementation methodology (target-audience and following intervention, materials to be used and key-messages and partners to mobilize) following the World Health Organisation standards. PMID:26061502

  3. Development of a training programme for home health care workers to promote preventive activities focused on a healthy lifestyle : an intervention mapping approach

    Walters, Maaike E.; Dijkstra, Arie; de Winter, Andrea F.; Reijneveld, Sijmen A.

    2015-01-01

    Background: Lifestyle is an important aspect in maintaining good health in older adults, and home health care (HHC) workers can play an important role in promoting a healthy lifestyle. However, there is limited evidence in the literature regarding how to develop an effective training programme to im

  4. The European Fusion Programme

    The European Fusion Programme is coordinated by Euratom and represents a long term cooperative project of Member States of the European Communities in the field of fusion, designed to lead to the joint construction of prototypes. The main lines of the programme proposed for 1982 to 1986 are: (1) the continuation of a strong effort on tokamaks with emphasis on JET construction, operation and upgrading, (2) conceptual design of NET and development of the related technology, and (3) further work on two alternative magnetic confinement systems. The current status and future plans for this programme are discussed in the paper. (author)

  5. Proposal of a programme for leisure education

    Urban, Jindřich

    2013-01-01

    The submitted bachelor thesis with the title of Proposal of a programme for leisure education reacts on urgent needs in the area of meaningful spending of young people's leisure time. By its practical focus, it represents selected ways for possible management of leisure time activity oriented on sport fishing. The main aim of the thesis is to propose programme for a fishing club, i.e. presentation of thirteen elaborated thematic areas that are considered as fundamental in fishing sport. E...

  6. The QUENCH programme at Forschungszentrum Karlsruhe (FZK)

    The QUENCH programme at FZK was launched to investigate the hydrogen source term during reflood of an overheated reactor core. It consists of large scale bundle experiments, separate-effects tests, modelling activities and application and validation of severe fuel damage (SFD) code systems. The paper describes the experimental part of the programme, namely the experimental facilities and test rigs as well as selected results obtained during the recent years. (author)

  7. Photovoltaic programme, edition 2004

    NONE

    2004-07-01

    This comprehensive publication issued by the Swiss Federal Office of Energy's Photovoltaics (PV) Programme presents an overview (in English) of activities and projects in the photovoltaics research and pilot and demonstration areas in Switzerland for the year 2003. Progress in future solar cell technologies as well as in the area of modules, building integration and system technologies is summarised. Also, national and international co-operation and multi-national pilot and demonstration projects are commented on. Associated projects such as eco-balances for PV systems, forecasting and modelling tools as well as system monitoring tools are discussed. In the area of pilot and demonstration projects, component development, PV integration in sloping roofs, on flat roofs and on facades as well as further PV plant are looked at. Also, measurement campaigns, studies, statistics and other PV-related topics are summarised. This volume presents a list of 92 projects in the PV area including the appropriate Internet links and is completed with a collection of project abstracts.

  8. Screening of preschool and school children for cystic fibrosis with the chloride electrode and neutron activation analysis. Part of a coordinated programme on medical applications of activation analysis

    A screening study was performed on 9,685 infants and children between 0 and 7 years of age living in the city of Istanbul. 2,511 of the subjects (''normals'') were kindergarten and school children and the remainder were children who had been brought to the casualty outpatient departments of two large hospitals. The purposes of the investigation were twofold, first to determine the prevalence of cystic fibrosis in a normal versus a sick population of children, and second to compare sweat-chloride vis-a-vis nail-sodium as indicators of the disease. Sweat-chloride was determined in all subjects by the use of a chloride specific electrode; nail sodium was determined in 1122 subjects by neutron activation analysis. These measurements led to the identification of seven cystic fibrosis cases in the outpatient group (frequency = 0.1%) and none in the kindergarten/school group. Sweat-chloride gave 0.7% false positives and no false negatives; nailsodium gave 14.7% false positives and 0.1% false negatives. It is concluded that nail-sodium is a much less effective indicator of cystic fibrosis than sweat-chloride and its use can probably not be justified except in certain special circumstances. Furthermore it would appear that the screening of outpatient cases rather than the whole population of children is a more cost-effective method for the detection of cystic fibrosis

  9. Experience from the Inspection of Licensees' Outage Activities, Including Fire Protection Programmes, Event Response Inspections, and the Impact of the Fukushima Daiichi NPP Accident on Inspection Programmes. Workshop Proceedings, Chattanooga, Tennessee, United States, 7-10 April 2014 - Appendix: Compilation of Survey Responses

    This appendix provides the complete compilation of responses received to the questionnaire issued in conjunction with the workshop announcements. The responses are provided as received, with changes made only to the formatting. The OECD Nuclear Energy Agency (NEA) Committee on Nuclear Regulatory Activities (CNRA) Working Group on Inspection Practices (WGIP) sponsored the 12. International Workshop on Nuclear Regulatory Inspection Activities. The workshop was hosted by the U.S. NRC, in Chattanooga, Tennessee, United States of America on 7 -10 April 2014. The three workshop topics that were addressed were as follows: - Inspection of Outage Activities Including Fire Protection Programmes. - Event Response Inspections. - The Impact of Inspection Programmes of the Fukushima Daiichi NPP Accident. Each of the respondents was given the following instructions in relation to their response: - Only one response per country is required. If more than one person from your country is participating, please co-ordinate the responses accordingly. - Please provide responses on separate sheet and clearly identify the questionnaire part and topic. For preparation of the workshop, participants are invited to supply their national inspection approaches used in inspection of events and incidents according to the surveys. Actual issues that were discussed during the workshop were generated by the topic leaders based on the responses submitted by participants with their registration forms. This formats helps to ensure that issues considered most important by the workshop participants are covered during the group discussions. (authors)

  10. The European Framework Programme under way

    2007-01-01

    The new European Framework Programme - FP7 - has recently started and will offer various possibilities for CERN to participate in EU co-funded projects for research and technological development. In December 2006, the Council of the European Union (EU) formally adopted the 7th European Framework Programme for research, technological development and demonstration activities (FP7). FP7 started on 1 January 2007 and will cover the period 2007 to 2013. With a total budget of 50.5 B-Euros, FP7 is the largest Framework Programme in the history of the EU. FP7 consists of four major sub-programmes, referred to as 'Specific Programmes'. 'Cooperation' is focused on collaborative research and is divided into 10 research themes. 'Ideas' is a new EU programme for funding of frontier research in all fields of science. 'Capacities' aims at strengthening the research capacities in Europe. Finally, 'People' succeeds the previous Marie Curie Programmes and targets the development of Europe's human potential. On 22 December...

  11. The European Framework Programme under way

    2007-01-01

    The new European Framework Programme - FP7 - has recently started and will offer various possibilities for CERN to participate in EU co-funded projects for research and technological development. In December 2006, the Council of the European Union (EU) formally adopted the 7th European Framework Programme for research, technological development and demonstration activities (FP7). FP7 started on 1st January 2007 and will cover the period 2007 to 2013. With a total budget of 50.5 billion euros, FP7 is the largest Framework Programme in the history of the EU. FP7 consists of four major sub-programmes, referred to as 'Specific Programmes'. 'Cooperation' is focused on collaborative research and is divided into 10 research themes. 'Ideas' is a new EU programme for funding frontier research in all fields of science. 'Capacities' aims at strengthening the research capacities in Europe. Finally, 'People' succeeds the previous Marie Curie Programmes and targets the development of Europe's human potential. On 22 Decem...

  12. Network virtualization and programmability

    Colle, Didier; Jooris, Bart; Gurzi, Pasquale; Pickavet, Mario; Demeester, Piet

    2010-01-01

    We present network virtualization (building virtual or logical networks over a physical infrastructure) and network programmability (allowing the network operator to at least control the network but more fundamentally to define its behavior) concepts.

  13. Elukestva õppe programm : Erasmus+

    2014-01-01

    Erasmus+ programm liidab senised koostööprogrammid „Euroopa elukestva õppe programm“, „Euroopa Noored“ ning Euroopa komisjoni rahvusvahelised kõrgharidusprogrammid. Elukestva õppe programmi 2013 kokkuvõte

  14. Fellows, Associates & Students Programmes

    2005-01-01

    The present document reviews the CERN Fellows, Associates and Students Programmes emphasizing the developments since 2000, when the previous review was presented to the Scientific Policy Committee, Finance Committee and Council (CERN/2325), and makes proposals for the coming five years. In summary, it is proposed to â?¢ Simplify the payment scheme for the Paid Scientific Associates Programme, which will no longer depend on candidateâ??s home support and age; â?¢ Broaden the scope of the Fellowship Programme, in order to facilitate the recruitment of young graduates in computing and engineering. Age-related eligibility conditions and payment levels will be replaced with experience-based criteria; â?¢ Modify subsistence rates for the Doctoral and Technical Student Programme in order to harmonize CERNâ??s payment levels with those offered by other research establishments. This document is presented for discussion and recommendation by the Scientific Policy Committee and approval by the Council. Additiona...

  15. The Gold Standard Programme

    Neumann, Tim; Rasmussen, Mette; Ghith, Nermin;

    2013-01-01

    To evaluate the real-life effect of an evidence-based Gold Standard Programme (GSP) for smoking cessation interventions in disadvantaged patients and to identify modifiable factors that consistently produce the highest abstinence rates.......To evaluate the real-life effect of an evidence-based Gold Standard Programme (GSP) for smoking cessation interventions in disadvantaged patients and to identify modifiable factors that consistently produce the highest abstinence rates....

  16. Stay Safe Programme

    MacIntyre, Deirdre; Carr, Alan.

    1999-01-01

    Objective. This child abuse prevention study aimed to evaluate the effectiveness of the Stay Safe Programme in training unscreened 7 and 10 year old children in personal safety skills. Subsidiary aims were to evaluate the programme's impact on children's self-esteem and parents' and teachers' knowledge and attitudes of relevance to child abuse and protection. Method. Changes in safety knowledge and skills and self-esteem of 339 children who participated in the Stay Safe Program...

  17. Punch Card Programmable Microfluidics

    George Korir; Manu Prakash

    2014-01-01

    Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers exist towards low-cost field deployment of programmable microfluidics. Incorporating multiple pumps, mixers and discrete valve based control of nanoliter fluids and droplets in an integrated, programmable manner without additional required external component...

  18. Effectiveness of a universal parental support programme to promote healthy dietary habits and physical activity and to prevent overweight and obesity in 6-year-old children: the Healthy School Start Study, a cluster-randomised controlled trial.

    Gisela Nyberg

    Full Text Available To develop and evaluate the effectiveness of a parental support programme to promote healthy dietary and physical activity habits and to prevent overweight and obesity in Swedish children.A cluster-randomised controlled trial was carried out in areas with low to medium socio-economic status. Participants were six-year-old children (n = 243 and their parents. Fourteen pre-school classes were randomly assigned to intervention (n = 7 and control groups (n = 7. The intervention lasted for 6 months and included: 1 Health information for parents, 2 Motivational Interviewing with parents and 3 Teacher-led classroom activities with children. Physical activity was measured by accelerometry, dietary and physical activity habits and parental self-efficacy through a questionnaire. Body weight and height were measured and BMI standard deviation score was calculated. Measurements were conducted at baseline, post-intervention and at 6-months follow-up. Group differences were examined using analysis of covariance and Poisson regression, adjusted for gender and baseline values.There was no significant intervention effect in the primary outcome physical activity. Sub-group analyses showed a significant gender-group interaction in total physical activity (TPA, with girls in the intervention group demonstrating higher TPA during weekends (p = 0.04, as well as in sedentary time, with boys showing more sedentary time in the intervention group (p = 0.03. There was a significantly higher vegetable intake (0.26 servings in the intervention group compared to the control group (p = 0.003. At follow-up, sub-group analyses showed a sustained effect for boys. The intervention did not affect the prevalence of overweight or obesity.It is possible to influence vegetable intake in children and girls' physical activity through a parental support programme. The programme needs to be intensified in order to increase effectiveness and sustain the effects long-term. These findings

  19. A 12-week after-school physical activity programme improves endothelial cell function in overweight and obese children: a randomised controlled study

    Park Jong-Hwan; Miyashita Masashi; Kwon Yoo-Chan; Park Hyun-Tae; Kim Eun-Hee; Park Jin-Kee; Park Ki-Beam; Yoon Suk-Ran; Chung Jin-Woong; Nakamura Yoshio; Park Sang-Kab

    2012-01-01

    Abstract Background Endothelial dysfunction is associated with childhood obesity and is closely linked to the amount and function of endothelial progenitor cells. However, it remains unclear whether endothelial progenitor cells increase with after-school exercise in overweight and obese children. The purpose of this study was to investigate the effects of an after-school exercise programme on endothelial cell function in overweight and obese children. Methods A total of 29 overweight/obese ch...

  20. Status of national gas cooled reactor programmes

    This report has been compiled as a central source of summary-level information on the present status of High Temperature Gas-Cooled Reactor (HTGR) programmes in the world and on future plans for the continued development and deployment of HTGRs. Most of the information concerns the programmes in the United States, Germany, Japan and the Soviet Union, countries that have had large programmes related to HTGR technology for several years. Summary-level information is also provided in the report on HTGR-related activities in several other countries who either have an increasing interest in the technology and/or who are performing some development efforts related to HTGR technology. The report contains a summary-level update on the MAGNOX and AGR programmes. This is the twelfth issue of the document, the first of which was issued in March, 1979. The report has been prepared in the IAEA Nuclear Power Technology Development Section. Figs and tabs

  1. Status of national programmes on fast reactors

    Based on the International Working Group on Fast reactors (IWGFR) members' request, the IAEA organized a special meeting on Fast Reactor Development and the Role of the IAEA in May 1993. The purpose of the meeting was to review and discuss the status and recent development, to present major changes in fast reactor programmes and to recommend future activities on fast reactors. The IWGFR took note that in some Member States large prototypes have been built or are under construction. However, some countries, due to their current budget constraints, have reduced the level of funding for research and development programmes on fast reactors. The IWGFR noted that in this situation the international exchange of information and cooperation on the development of fast reactors is highly desirable and stressed the importance of the IAEA's programme on fast reactors. These proceedings contain important and useful information on national programmes and new developments in sodium cooled fast reactors in Member States. Refs, figs and tabs

  2. IAEA programme on research reactor safety

    This paper describes the IAEA programme on research reactor safety and includes the safety related areas of conversions to the use of low enriched uranium (LEU) fuel. The program is based on the IAEA statutory responsibilities as they apply to the requirements of over 320 research reactors operating around the world. The programme covers four major areas: (a) the development of safety documents; (b) safety missions to research reactor facilities; (c) support of research programmes on research reactor safety; (d) support of Technical Cooperation projects on research reactor safety issues. The demand for these activities by the IAEA member states has increased substantially in recent years especially in developing countries with increasing emphasis being placed on LEU conversion matters. In response to this demand, the IAEA has undertaken an extensive programme for each of the four areas above. (author)

  3. The volunteer programme ‘Night Ravens’:

    Larsen, Britt Østergaard; Bendix Kleif, Helle; Kolodziejczyk, Christophe

    2015-01-01

    with NR organizations to districts without NR organizations. The results show no difference in the crime rates between Danish postcode districts with and without the NR programme. Hence, we cannot identify positive effects of situational crime prevention when evaluating this Scandinavian volunteer......The volunteer programme ‘Night Ravens’ (NR) was founded in Sweden in 1987 and has, over the years, developed into a Scandinavian concept covering large areas of Sweden, Denmark, Norway, Greenland and the Faroe Islands. The NR programme is a crime prevention initiative with adults walking the...... streets at night in identifiable ‘uniforms’ in areas with high activity. The purpose of this study is to evaluate the effects of the NR programme in Denmark based on a volunteer set-up with a less intrusive approach to situational crime prevention than, for instance, hot spot policing. The analyses are...

  4. The CERN & Society programme launches its newsletter

    Matteo Castoldi

    2016-01-01

    The newsletter will be issued quarterly. Sign up to remain informed about the latest initiatives of the CERN & Society programme!    The CERN & Society programme encompasses projects in the areas of education and outreach, innovation and knowledge exchange, and culture and creativity that spread the CERN spirit of scientific curiosity for the inspiration and benefit of society. The programme is funded primarily by the CERN & Society Foundation, a charitable foundation established by CERN and supported by individuals, trusts, organisations and commercial companies. The projects are inspired or enabled by CERN but lie outside of the Laboratory’s specific research mandate. We especially want to help young talent from around the world to flourish in the future. The programme is now launching its newsletter, which will be issued quarterly. Everybody who wants to be informed about CERN & Society’s activities, stay up-to-date with its latest in...

  5. Experiences from TVO's Communication Programme

    In parallel with the field investigations of three sites, TVO has a specific information project aiming at public acceptance of HLW disposal in Finland. The site or final disposal will be selected by the year 2000. Prerequisites are that the local council accepts the facility, and that there is political acceptance of final disposal in the government and in Parliament TVO's experience with communications programmes concerning the siting of the spent fuel disposal facility is discussed. Much experience was gained from the 1987-92 information programme. Another programme was organised for the period 1993-96 to back up site investigations, development of technology and safety studies, and to pave the way for information activities in the years 1997-2000. The results of a study carried out a Jysaeskylae University on TVO's waste information in the candidate areas will provide useful information on attitudes about nuclear waste management in Finland. The issue of communication with local opponents, and strategies to assist in lessening their impact is discussed. It should be noted that in 1995 an amendment to the Finnish Nuclear Energy Act became effective that prohibits the transformation of Loviisa spent fuel from Finland to Russia after 1996, and thus reinforces the moral argument. (authors)

  6. Outcomes-based planning and implementation led to the success of the Hawaii fruit fly suppression programme: Implications to adoption of area-wide programmes

    Full text: A critical component of successful area-wide pest management (AWPM) programmes are organised, coordinated and comprehensive outreach educational programmes. The Hawaii area-wide fruit fly pest management (HAW-FLYPM) programme's educational programme, a part of a USDA AWPM programme in Hawaii, utilised the 'logic model' approach to organise, plan, execute and evaluate farmer and community educational programmes statewide. The logic model approach was an outcome-driven rather than activity based method that employed a linear sequence that developed relationships between programme inputs, outputs and outcomes. This model was utilised extensively to transfer sustainable, science-based technologies to suppress tephritid fruit fly pests. HAW-FLYPM's educational programme targeted growers and community door yard growers, three teaching curricula aimed at elementary through high school students, and a statewide awareness programme for the public at large. Additional key components of the HAW-FLYPM education programme was the development of implementation schedules used to track programme progress, a comprehensive media matrix developed to ensure educational materials met the needs of target audience groups, and a sustainability calculator to assess the likelihood of programme sustainability after the initial five year funding cycle. The model served as a 'blue print' for ensuring programme elements were planned, delivered and executed on a timely basis. Utilisation of the logic model to organise efforts and manage diverse, multi agency programmes such as the HAW-FLYPM programme has shown to be a successful method of programme advancement and outcome achievement. (author)

  7. Effect of Final Kissing Balloon Dilatation after One-stent Technique at Left-main Bifurcation: A Single Center Data

    Zhan Gao; Bo Xu; Yue-Jin Yang; Shu-Bin Qiao; Yong-Jian Wu; Tao Chen; Liang Xu

    2015-01-01

    Background:Whether final kissing balloon (FKB) dilatation after one-stent implantation at left-main (LM) bifurcation site remains unclear.Therefore,this large sample and long-term follow-up study comparatively assessed the impact of FKB in patients with unprotected LM disease treated with one-stent strategy.Methods:Total 1528 consecutive patients underwent LM percutaneous coronary intervention in one center from January 2004 to December 2010 were enrolled; among them,790 patients treated with one drug-eluting stent crossover LM to left anterior descending (LAD) with FKB (n =230) or no FKB (n =560) were comparatively analyzed.Primary outcome was the rate of major adverse cardiovascular events,defined as a composite of death,myocardial infarction (MI) and target vessel revascularization (TVR).Results:Overall,The prevalence of true bifurcation lesions,which included Medina classification (1,1,1),(1,0,1),or (0,1,1),was similar between-groups (non-FKB:37.0% vs.FKB:39.6%,P =0.49).At mean 4 years follow-up,rates of major adverse cardiovascular events (non-FKB:10.0% vs.FKB:7.8%,P =0.33),death,MI and TVR were not significantly different between-groups.In multivariate propensity-matched regression analysis,FKB was not an independent predictor of adverse outcomes.Conclusions:For patients treated with one-stent crossover LM to LAD,clinical outcomes appear similar between FKB and non-FKB strategy.

  8. Position of the kissing-loop interaction associated with PTE-type 3’CITEs can affect enhancement of cap-independent translation

    Chattopadhyay, Maitreyi; Kuhlmann, Micki M.; Kumar, Kalyani; Simon, Anne E.

    2014-01-01

    The Panicum mosaic virus-like translation enhancer (PTE) functions as a cap-independent translation enhancer (3’CITE) in members of several Tombusviridae genera including 7/19 carmoviruses. For nearly all PTE, a kissing-loop connects the element with a hairpin found in several conserved locations in the genomic RNA (5’ terminal hairpin or ~100 nt from the 5’end) and small subgenomic RNA (~63 nt from the 5’end). Moving the interaction closer to the 5’end in reporter mRNAs using Saguaro cactus ...

  9. Finnish Fusion Research Programme Yearbook 1993-1994

    Finnish Fusion Research Programme (FFUSION) is one of the national energy research programmes funded by the Ministry of Trade and Industry and from 1995 by TEKES. National organization for fusion research is necessary for efficient and successful participation in international fusion programmes. FFUSION programme serves well for this purpose and it made possible to establish relations and the dialogue with the European Fusion Programme. The process led to the Finnish Association Euratom-TEKES in early 1995. The first period of the FFUSION programme (1993-1994) was preparation for the association to the Community Programme. The strategy was to emphasize fusion technology parallel with the basic fusion and plasma physics and to activate the related Finnish industry to collaborate and participate in the FFUSION programme and later in the European Fusion Programme. The key element in the strategy is the focusing our fairly small R and D effort to a few topics, which increases possibilities to be competitive in Europe. The physics programme in FFUSION deals mainly with theoretical and computational studies of radio-frequency heating in tokamak plasmas. Technology programme started with prestudies in 1993 and it concentrates into two areas: fusion reactor materials and remote handling systems. (8 figs., 3 tabs.)

  10. Punch Card Programmable Microfluidics

    Korir, George

    2014-01-01

    Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers exist towards low-cost field deployment of programmable microfluidics. Incorporating multiple pumps, mixers and discrete valve based control of nanoliter fluids and droplets in an integrated, programmable manner without additional required external components has remained elusive. Combining the idea of punch card programming with arbitrary fluid control, here we describe a self-contained, hand-crank powered, multiplex and robust programmable microfluidic platform. A paper tape encodes information as a series of punched holes. A mechanical reader/actuator reads these paper tapes and correspondingly executes a series of operations onto a microfluidic chip coupled to the platform in a plug-and-play fashion. Enabled by the complexity of codes that can be represented by a series ...

  11. External Mobility Programme

    HR Department

    2007-01-01

    Every year, a significant number of highly-skilled staff members leave the Organization and offer their talents on the European job market. CERN is launching a programme aiming to help staff members to whom the Organization cannot offer an indefinite contract in the transition towards their next employment. The programme, which is based on the establishment of a number of partnerships with potential employers in the private sector, will run on a voluntary basis. Staff members who have received confirmation that they will not be offered an indefinite contract and who are interested in availing themselves of the opportunities offered by the programme, are invited to enrol by following the procedure described at: https://ert.cern.ch/browse_intranet/wd_pds?p_web_page_id=5841 Applications will be processed in the strictest confidence by the Human Resources Department and eligible profiles will then be made available to partner companies for recruitment purposes. Any subsequent ...

  12. The French nuclear programme

    EDF has long been interested in the use of nuclear energy for thermal power generation. After a period of apprenticeship and experiments, EDF launched a major PWR plant programme so as to reduce France's energy dependence and master generation costs. This programme, based on standardization, has achieved the desired results. It must now be adapted to suit the needs of the 21st century. For this programme, all those involved (Governmental authorities, EDF, manufacturers) were mobilized to an unprecedented extent and rigorous working methods were imposed. Experience feedback has been used to make improvements both to the installations themselves and to procedures. Results have proved satisfactory as regards nuclear safety but vigilance must be maintained. Public opinion on nuclear power is reserved we are sentenced to achieving a 'fault-free' track record, all the while mastering costs, so as to ensure the continuing use of nuclear energy. (author)

  13. Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK

    Yang Min

    2011-10-01

    Full Text Available Abstract Background Low levels of physical activity in children have been linked to an increased risk of obesity, but many children lack confidence in relation to exercise (exercise self-efficacy. Factors which can impact on confidence include a chronic health condition such as asthma, poor motor skills and being overweight. Increasing levels of physical activity have obvious benefits for children with asthma and children who are overweight, but few activity interventions with children specifically target children with low exercise self-efficacy (ESE. This study aims to evaluate the efficacy and feasibility of a schools-based activity programme suitable for children with risk factors for adult obesity, including asthma, overweight and low exercise self-efficacy. Methods/Design A clustered (at the level of school RCT will be used to compare a targeted, 10 week, stepped activity programme (activity diary, dance DVD, circuit-training and motivational interviewing designed to promote ESE. We will recruit 20 primary schools to participate in the intervention and 9-11 year old children will be screened for low levels of ESE, asthma and overweight. In order to provide sufficient power to detect a difference in primary outcomes (Body Mass Index-BMI & ESE at 12 month follow-up between children in the intervention schools and control schools, the target sample size is 396. Assessments of BMI, ESE, waist circumference, peak flow, activity levels and emotional and behavioural difficulties will be made at baseline, 4 months and 12 month follow-up. Discussion We aim to increase ESE and levels of physical activity in children with risk factors for adult obesity. The outcomes of this study will inform policy makers about the feasibility, acceptability and effectiveness of delivering targeted health interventions within a school setting. Trial Registration ISRCTN Register no. ISRCTN12650001

  14. A 12-week after-school physical activity programme improves endothelial cell function in overweight and obese children: a randomised controlled study

    Park Jong-Hwan

    2012-07-01

    Full Text Available Abstract Background Endothelial dysfunction is associated with childhood obesity and is closely linked to the amount and function of endothelial progenitor cells. However, it remains unclear whether endothelial progenitor cells increase with after-school exercise in overweight and obese children. The purpose of this study was to investigate the effects of an after-school exercise programme on endothelial cell function in overweight and obese children. Methods A total of 29 overweight/obese children (12.2 ± 0.1 years were randomly divided into control (i.e. no after-school exercise, n = 14 and after-school exercise (n = 15 groups. The 12-week after-school exercise intervention consisted of 3 days of combined aerobic and resistance exercise per week. Each 80-minute exercise programme included 10 minutes of warm-up and 10 minutes of cool-down after school. CD34+ (a cell surface marker on hematopoietic stem cells, CD133+ (a cell surface marker on hematopoietic progenitor cells and CD34+/CD133+ (considered as endothelial progenitor cells were measured at baseline and after 12 weeks using flow cytometry. Results Increased percentages of CD34+, CD133+ and CD34+/CD133+ cells were observed in the after-school exercise group (p = 0.018; p = 0.001; p = 0.002, respectively compared with the control group. Carotid intima-media thickness decreased after 12 weeks in the after-school exercise group (p = 0.020 compared with the control group. Conclusions This study provides preliminary evidence that a combined after-school exercise programme may represent an effective intervention strategy for improving vascular repair and endothelial cell function, leading to improved cardiovascular health in overweight and obese children. Trial registration Current Controlled Trials ISRCTN19037201

  15. Framework Programmable Platform for the Advanced Software Development Workstation (FPP/ASDW). Demonstration framework document. Volume 1: Concepts and activity descriptions

    Mayer, Richard J.; Blinn, Thomas M.; Dewitte, Paul S.; Crump, John W.; Ackley, Keith A.

    1992-01-01

    The Framework Programmable Software Development Platform (FPP) is a project aimed at effectively combining tool and data integration mechanisms with a model of the software development process to provide an intelligent integrated software development environment. Guided by the model, this system development framework will take advantage of an integrated operating environment to automate effectively the management of the software development process so that costly mistakes during the development phase can be eliminated. The Advanced Software Development Workstation (ASDW) program is conducting research into development of advanced technologies for Computer Aided Software Engineering (CASE).

  16. Funktionell Programmering : En framtidsprognos

    Holmer, Mattias

    2011-01-01

    Trenden inom systemutveckling och programutveckling går mot ett mer användande av multi programmeringsparadigmer. Funktionell programmering har fått mer uppmärksamhet på senare tid och utvecklingen tycks över lag gå än mer åt det deklarativa hållet där programmeraren fokuserar mer på vad som skall utföras och inte lika mycket på hur. Under en tid har det objektorienterade paradigmet varit dominerande, kommer det vara så i framtiden? Funktionell programmering skiljer sig från imperativ program...

  17. A programmer's geometry

    Bowyer, Adrian

    1983-01-01

    A Programmer's Geometry provides a guide in programming geometric shapes. The book presents formulas and examples of computer representation and coding of geometry. Each of the nine chapters of the text deals with the representation and solution of a specific geometrical problem, such as areas, vectors, and volumes. The last chapter provides a brief discussion on generating image through a computer. The codes presented in the book are written in FORTRAN 77. The text will be of great use to programmers who are working on projects that involve geometric calculations.

  18. Computer mathematics for programmers

    Abney, Darrell H; Sibrel, Donald W

    1985-01-01

    Computer Mathematics for Programmers presents the Mathematics that is essential to the computer programmer.The book is comprised of 10 chapters. The first chapter introduces several computer number systems. Chapter 2 shows how to perform arithmetic operations using the number systems introduced in Chapter 1. The third chapter covers the way numbers are stored in computers, how the computer performs arithmetic on real numbers and integers, and how round-off errors are generated in computer programs. Chapter 4 details the use of algorithms and flowcharting as problem-solving tools for computer p

  19. Elemental activation analysis with decay and prompt gamma ray techniques, using isotopic neutron sources and a nuclear research reactor. Part of a coordinated programme on nuclear-based techniques in geology and mineral prospecting

    This is to review the research activities carried out through the IAEA research Project 1697/RB ''Elemental activation analysis with decay and prompt gamma ray techniques, using isotopic neutron sources and the nuclear research reactor. The programme of work includes: a) Development of decay and prompt gamma ray activation techniques for mineral exploration. b) Development of epithermal NAA in addition to thermal NAA especially for gold ore. c) Development of non-destructive insitu elemental analysis with decay and prompt gamma ray techniques using isotopic neutron sources. A joint programme has been established with the Egyptian Geological Surrey and Mining Authority for using nuclear techniques in evaluating gold prospects of several ancient gold mines and investigating several tin-tantalum deposits, which were discovered over the last few years. Two sources of neutrons were used for irradiation, one of the dry channels of the two megawatts research reactor, ET-RR-1 for laboratory studies, and a Pu-Be neutron source in paraffin assembly for possible insitu work

  20. International Programmes on ADS: IAEA

    The IAEA recognizes that there are four major challenges facing the long term development of nuclear energy as a part of the world’s energy mix: improvement of the economic competitiveness, meeting increasingly stringent safety requirements, adhering to the criteria of sustainable development, and public acceptance. Meeting the sustainability criteria is the driving force behind IAEA’s activity in the area of innovative transmutation reactor technology development and, in particular, Accelerator Driven Systems. The framework for all the IAEA activities in the ADS area is the Technical Working Group on Fast Reactors (TWG-FR). In response to strong common R&D needs in the Member States, the TWG-FR acts as a catalyst for international information exchange and collaborative R&D. It provides a forum for exchange of non-commercial scientific and technical information, and a forum for international cooperation on generic research and development programmes on advances in fast reactors and fast spectrum accelerator driven systems. Its present members are the following 15 IAEA Member States: Belarus, Brazil, China, France, Germany, India, Italy, Japan, Kazakhstan, Republic of Korea, Russian Federation, Sweden, Switzerland, United Kingdom, and United States of America, as well as 3 international organizations: ISTC, OECD-NEA, and EU (EC). As observers, the TWG-FR has welcomed Argentina and Belgium. Last but not least, the IAEA is providing the ADS Research and Development Database. It contains information about ADS related R&D programmes, existing and planned experimental facilities as well as programmes, methods and data development efforts, design studies, and so forth

  1. Supporting mothers: issues in a Community Mothers Programme

    O'Connor, Pat

    2001-01-01

    peer-reviewed This article describes a community support programme which implicitly challenges the assumption that the existence of a partner and local kin obviates the need to support women when they come home from hospital with a new baby. Implicit in the programme is the idea that support by mothers, of mothers, validates the activity of child care and is one way of facilitating the child's development. This programme was successful in terms of its perceived impact on both the providers...

  2. Importance of outcomes Measurement of CSR programmes - Case Nokia

    Talvitie-Sirén, Reeta

    2009-01-01

    Abstract: Objectives of the Thesis The objective of the thesis was to find out how companies measure the societal and business outcomes of their CSR activities as well as to find out the reasons why outcomes measurement is considered important. The focus was on the societal aspect of CSR, and all programmes studied were community related CSR programmes. The programmes studied were categorised according to a framework of CSR action types modified from Halme and Laurila (2009). A fourth cate...

  3. Natural variation in rosette size under salt stress conditions corresponds to developmental differences between Arabidopsis accessions and allelic variation in the LRR-KISS gene

    Julkowska, Magdalena M.

    2016-02-11

    Natural variation among Arabidopsis accessions is an important genetic resource to identify mechanisms underlying plant development and stress tolerance. To evaluate the natural variation in salinity stress tolerance, two large-scale experiments were performed on two populations consisting of 160 Arabidopsis accessions each. Multiple traits, including projected rosette area, and fresh and dry weight were collected as an estimate for salinity tolerance. Our results reveal a correlation between rosette size under salt stress conditions and developmental differences between the accessions grown in control conditions, suggesting that in general larger plants were more salt tolerant. This correlation was less pronounced when plants were grown under severe salt stress conditions. Subsequent genome wide association study (GWAS) revealed associations with novel candidate genes for salinity tolerance such as LRR-KISS (At4g08850), flowering locus KH-domain containing protein and a DUF1639-containing protein. Accessions with high LRR-KISS expression developed larger rosettes under salt stress conditions. Further characterization of allelic variation in candidate genes identified in this study will provide more insight into mechanisms of salt stress tolerance due to enhanced shoot growth.

  4. Aminoglycoside binding to the HIV-1 RNA dimerization initiation site: thermodynamics and effect on the kissing-loop to duplex conversion.

    Bernacchi, Serena; Freisz, Séverine; Maechling, Clarisse; Spiess, Bernard; Marquet, Roland; Dumas, Philippe; Ennifar, Eric

    2007-01-01

    Owing to a striking, and most likely fortuitous, structural and sequence similarity with the bacterial 16 S ribosomal A site, the RNA kissing-loop complex formed by the HIV-1 genomic RNA dimerization initiation site (DIS) specifically binds 4,5-disubstituted 2-deoxystreptamine (2-DOS) aminoglycoside antibiotics. We used chemical probing, molecular modeling, isothermal titration calorimetry (ITC) and UV melting to investigate aminoglycoside binding to the DIS loop-loop complex. We showed that apramycin, an aminoglycoside containing a bicyclic moiety, also binds the DIS, but in a different way than 4,5-disubstituted 2-DOS aminoglycosides. The determination of thermodynamic parameters for various aminoglycosides revealed the role of the different rings in the drug-RNA interaction. Surprisingly, we found that the affinity of lividomycin and neomycin for the DIS (K(d) approximately 30 nM) is significantly higher than that obtained in the same experimental conditions for their natural target, the bacterial A site (K(d) approximately 1.6 microM). In good agreement with their respective affinity, aminoglycoside increase the melting temperature of the loop-loop interaction and also block the conversion from kissing-loop complex to extended duplex. Taken together, our data might be useful for selecting new molecules with improved specificity and affinity toward the HIV-1 DIS RNA. PMID:17942426

  5. Mexican medfly programme

    This film tells the story of the fight against and final extinction of the Mediterranean fruit-fly (Ceratitis capitata) in Mexico. By producing billions of high quality sterile flies in the Medfly reproduction and sterilization laboratory in the province of Chiapas and releasing them over infested areas, the Moscamed Programme succeeded in eradicating this pest from Mexico in 1982

  6. Kulturalistische Unternehmensethik : ein Programm

    Hanekamp, Gerd

    2001-01-01

    "Das Programm einer kulturalistischen Unternehmensethik wird vorgestellt. Es gründet auf einem philosophischen Ansatz, der sich als instrumentalistisch, kontextualistisch, transsubjektivistisch und individualistisch charakterisieren lässt. Hinsichtlich der ethischen Grundlagen werden starke Thesen durch den Rekurs auf eine kontextualistisch-normative Anthropologie vermieden." (Autorenreferat)

  7. Air Quality Monitoring Programme

    Kemp, K.; Palmgren, F.

    The Danish Air Quality Monitoring Programme (LMP IV) has been revised in accordance with the Framework Directive and the first three daughter directives of SO2, NOx/NO2, PM10, lead, benzene, CO and ozone. PM10 samplers are under installation and the installation will be completed during 2002...

  8. En model for programmer

    Christensen, Henrik Bærbak

    Dette undervisningsmateriale beskriver en model for, hvordan programmer er opbygget. Materialet er skrevet til brug i det gymnasiale forsøgsfag Informationsteknologi. Seneste version af dette undervisningsmateriale kan findes på http:// www.imhotep.dk. Tak til Elisabeth Husum for en kritisk...

  9. Turkey's Basic Education Programme

    A. Remzi Sezgin

    2000-01-01

    In August 1997, the Government of Turkey greatly increased its efforts to implement eight-year obligatory education, through parliamentary approval of Law No. 4306 for Basic Education. The law mobilises significant resources for a major investment in school facilities through earmarked taxes, establishes a timetable for the Basic Education Programme and streamlines procedures to allow for swift action and implementation.

  10. Fast reactor programme

    This progress report summarises the fast reactor research carried out at the Netherlands Energy Research Centre during the year 1981. The neutron and fission product cross sections of various isotopes have been evaluated. In the fuel performance programme, some preliminary results are given and irradiation facilities described. Creep experiments on various stainless steel components are reported

  11. The Productive Programmer

    Ford, Neal

    2009-01-01

    Anyone who develops software for a living needs a proven way to produce it better, faster, and cheaper. The Productive Programmer offers critical timesaving and productivity tools that you can adopt right away, no matter what platform you use. Master developer Neal Ford details ten valuable practices that will help you elude common traps, improve your code, and become more valuable to your team.

  12. The European Programme Manager

    Larson, Anne; Bergman, E.; Ehlers, S.;

    The publication is a result of a cooperation between organisations in six European countries with the aim to develop a common European education for programme managers. It contains of a description of the different elements of the education together with a number of case-studies from the counties...... involved in the cooperation (Finland, Denmark, Portugal, Iceland, United Kingdom and Austria)....

  13. A special evaluation: The ARCAL programme

    The Regional Co-operative Arrangements for the Promotion of Nuclear Science and Technology in Latin America, ARCAL, came into being in 1983. At a meeting held in Vienna in September 1984, ten Latin American countries agreed to participate in the programme, the Guidelines setting up the structure of the programme were approved and nine areas of development were identified to initiate project activities. The programme, which is now in its second phase and in its ninth year of implementation, has 17 Member States and includes fifteen projects. Total disbursements under the ARCAL programme during the period 1983 - 1991 amounted to $8.5 million, including $5.4 million from the Technical Assistance and Co-operation Fund (TACF), $2.2 million from extrabudgetary sources, and some $0.9 million in the form of in-kind contributions. As of September 1992, equipment totaling $3.5 million, 385 man-months of expert services, and 108 fellowships for approximately 150 man-months of training had been provided to ARCAL Member States within the context of fifteen ARCAL projects. In addition, 1844 Latin Americans were trained in 194 ARCAL training courses. The evaluation concluded that, as a result of the ARCAL programme, there is now better knowledge in participating countries about nuclear techniques and technology, as well as greater awareness at most levels of the importance of radiological safety and of the need to implement radiation protection measures, both a the national and at the regional level. The programme has contributed to developing and/or improving capabilities in the region in various applications of nuclear techniques through training activities. The programme has further allowed the establishment of regional collaborative links, particularly between countries with similar interests, in important fields of application, such as agriculture and nuclear medicine. Figs and tabs

  14. Three years of an intensive Programme

    Pedersen, Jens Myrup; Lopez, Jose Manuel Guterrez Lopez; Kirikova, Marite; Zabludowski, Lukasz; Comellas, Jaume

    This paper summarizes valuable experiences and learning points from three years of the Erasmus funded Intensive Programme on “Implementing Europe’s Future Broadband Infrastructure”. The programme consisted of a course held each year 2012-2014 during two weeks of July, where 30-35 students and 10......-12 teachers from the 4 participating universities would meet in the location of one of the partner institutions. During the three years, the programme was each year adjusted according to the observations and evaluations from the previous year. The course was organized as a week of course modules, followed by...... encourage (or enforce) the students to mix and work together throughout the course activities. Finally, we found that the model of combining course modules and projects worked well, especially if active learning approaches were used in the course modules. Keywords: Problem Based Learning...

  15. Planning environmental sanitation programmes in emergencies.

    Harvey, Peter A; Reed, Robert A

    2005-06-01

    Environmental sanitation programmes are vital for tackling environmental-related disease and ensuring human dignity in emergency situations. If they are to have maximum impact they must be planned in a rapid but systematic manner. An appropriate planning process comprises five key stages: rapid assessment and priority setting; outline programme design; immediate action; detailed programme design; and implementation. The assessment should be based on carefully selected data, which are analysed via comparison with suitable minimum objectives. How the intervention should be prioritised is determined through objective ranking of different environmental sanitation sector needs. Next, a programme design outline is produced to identify immediate and longer-term intervention activities and to guarantee that apposite resources are made available. Immediate action is taken to meet acute emergency needs while the detailed programme design takes shape. This entails in-depth consultation with the affected community and comprehensive planning of activities and resource requirements. Implementation can then begin, which should involve pertinent management and monitoring strategies. PMID:15910646

  16. Mammographic screening programmes in Europe

    Giordano, Livia; von Karsa, Lawrence; Tomatis, Mariano; Majek, Ondrej; de Wolf, Chris; Lancucki, Lesz; Hofvind, Solveig; Nyström, Lennarth; Segnan, Nereo; Ponti, Antonio; Van Hal, G; Martens, P; Májek, O; Danes, J; von Euler-Chelpin, My Catarina; Aasmaa, A; Anttila, A; Becker, N; Péntek, Z; Budai, A; Mádai, S; Fitzpatrick, P; Mooney, T; Zappa, M; Ventura, L; Scharpantgen, A; Hofvind, S; Seroczynski, P; Morais, A; Rodrigues, V; Bento, M J; Gomes de Carvalho, J; Natal, C; Prieto, M; Sánchez-Contador Escudero, C; Zubizarreta Alberti, R; Fernández Llanes, S B; Ascunce, N; Ederra Sanza, M; Sarriugarte Irigoien, G; Salas Trejo, D; Ibáñez Cabanell, J; Wiege, M; Ohlsson, G; Törnberg, S; Korzeniewska, M; de Wolf, C; Fracheboud, J; Patnick J, J; Lancucki, L; Ducarroz, S; Suonio, E

    To summarize participation and coverage rates in population mammographic screening programmes for breast cancer in Europe.......To summarize participation and coverage rates in population mammographic screening programmes for breast cancer in Europe....

  17. Donor transplant programme

    The transplantation of organs and tissues from one human to another human has become an essential and well established form of therapy for many types of organ and tissue failure. In Malaysia, kidney, cornea and bone marrow transplantation are well established. Recently, liver, bone and heart transplanation have been performed. Unfortunately, because of the lack of cadaveric organ donation, only a limited number of solid organ transplantation have been performed. The cadaveric organ donor rate in Malaysia is low at less than one per million population. The first tissue transplanted in Malaysia was the cornea which was performed in the early 1970s. At that time and even now the majority of corneas came from Sri Lanka. The first kidney transplant was performed in 1975 from a live related donor. The majority of the 629 kidney transplants done at Hospital Kuala Lumpur to date have been from live related donors. Only 35 were from cadaver donors. Similarly, the liver transplantation programme which started in 1995 are from live related donors. A more concerted effort has been made recently to increase the awareness of the public and the health professionals on organ and tissue donation. This national effort to promote organ and tissue donation seems to have gathered momentum in 1997 with the first heart transplant successfully performed at the National Heart Institute. The rate of cadaveric donors has also increased from a previous average of I to 2 per year to 6 per year in the last one year. These developments are most encouraging and may signal the coming of age of our transplantati on programme. The Ministry of Health in conjunction with various institutions, organizations and professional groups, have taken a number of proactive measures to facilitate the development of the cadaveric organ donation programme. Efforts to increase public awareness and to overcome the negative cultural attitude towards organ donation have been intensified. Equally important are efforts

  18. The INTEGRAL Core Observing Programme

    Winkler, C.; Gehrels, N.; Lund, Niels; Schonfelder, V.; Ubertini, P.

    The Core Programme of the INTEGRAL mission is defined as the portion of the scientific programme covering the guaranteed time observations for the INTEGRAL Science Working Team. This paper describes the current status of the Core Programme preparations and summarizes the key elements of the...

  19. Fusion technology programme

    The KfK-Association has continued work on 17 R and D contracts of the Fusion Technology Programme. An effort of 94 manyears per year is at present contributed by 10 KfK departments, covering all aereas defined in the Fusion Technology Programme. The dominant part of the work is directed towards the need of the NET design or supporting experiments. Some additional effort addresses long term technological issues and system studies relevant to DEMO or confinement schemes alternative to tokamaks. Direct contribution to the NET team has increased by augmentation of NET study contracts and delegation of personnel, three KfK delegates being at present members of the NET team. In reverse, specifications and design guidelines worked out by NET have started to have an impact on the current R and D-work in the laboratory. (orig./GG)

  20. Pharmacovigilance programme of India

    Kalaiselvan Vivekanandan

    2012-01-01

    Full Text Available The monitoring and reporting of adverse drug reactions (ADRs through pharmacovigilance is vital to patient safety and rational prescribing. In India, Central Drugs Standard Control Organization (CDSCO initiated Pharmacovigilance Programme of India (PvPI to report ADRs through ADRs monitoring centres in India. Indian Pharmacopoeia Commission (IPC is functioning as National Coordination Centre (NCC for PvPI. The ADRs are reported to NCC through VigiFlow by various centres are evaluated and committed to Uppsala Monitoring Centre, Sweden. The potential benefit of the PvPI is aimed to reducing or eliminating a harm of medicine. Continuous efforts of the healthcare professionals and the patients are expected to make this as one of the most successful and effective programmes. The present article updates the status and future plan of PvPI.

  1. VTT Energy`s new gasification and pyrolysis technology programme

    Kurkela, E. [IMEC, Leuven (Belgium)

    1997-12-31

    The publicly funded gasification and pyrolysis research activities of the Technical Research Centre of Finland (VTT) have been integrated into three-year programme, known as PROGAS, to promote Finnish gasification and pyrolysis R and D and improve contacts with companies that utilize these technologies. The programme will focus on applied technical research and on process and equipment development carried out with industry

  2. Economic viability of new launched school lunch programmes

    Jensen, Jørgen Dejgård; Smed, Sinne; Mørkbak, Morten Raun;

    2013-01-01

    activities related to the schools’ support and the users’ feeling of ownership, as well as internal professionalism and leadership in the implementation of the school lunch programme are important for the viability of the programme. Strong performance on the latter factors might to some extent compensate for...... the gap between cost and users’ willingness to pay for school lunches....

  3. Key United States programmes for the security of radioactive sources

    The paper discusses key US programme activities related to the security of radioactive sources, including both domestic and international programmes; the US Department of Energy-Nuclear Regulatory Commission joint report and findings; and critical partnerships for future efforts to preclude terrorist attacks using radioactive sources. (author)

  4. IAEA education and training programme in nuclear safety

    This paper presents the IAEA education and training (E and T) programme in nuclear safety. A strategic planning for the programme implementation is described in terms of objectives, outputs and activities. A framework based on areas of competency and the level of depth of the training is presented as well as the main achievements to date. (author)

  5. The Italian hydrogen programme

    Hydrogen could become an important option in the new millennium. It provides the potential for a sustainable energy system as it can be used to meet most energy needs without harming the environment. In fact, hydrogen has the potential for contributing to the reduction of climate-changing emissions and other air pollutants as it exhibits clean combustion with no carbon or sulphur oxide emissions and very low nitrogen oxide emissions. Furthermore, it is capable of direct conversion to electricity in systems such as fuel cells without generating pollution. However, widespread use of hydrogen is not feasible today because of economic and technological barriers. In Italy, there is an ongoing national programme to facilitate the introduction of hydrogen as an energy carrier. This programme aims to promote, in an organic frame, a series of actions regarding the whole hydrogen cycle. It foresees the development of technologies in the areas of production, storage, transport and utilisation. Research addresses the development of technologies for separation and sequestration of CO2, The programme is shared by public organisations (research institutions and universities) and national industry (oil companies, electric and gas utilities and research institutions). Hydrogen can be used as a fuel, with significant advantages, both for electric energy generation/ co-generation (thermo-dynamic cycles and fuel cells) and transportation (internal combustion engine and fuel cells). One focus of research will be the development of fuel cell technologies. Fuel cells possess all necessary characteristics to be a key technology in a future economy based on hydrogen. During the initial phase of the project, hydrogen will be derived from fossil sources (natural gas), and in the second phase it will be generated from renewable electricity or nuclear energy. The presentation will provide a review of the hydrogen programme and highlight future goals. (author)

  6. Neural Programmer-Interpreters

    Reed, Scott; De Freitas, Nando

    2015-01-01

    We propose the neural programmer-interpreter (NPI): a recurrent and compositional neural network that learns to represent and execute programs. NPI has three learnable components: a task-agnostic recurrent core, a persistent key-value program memory, and domain-specific encoders that enable a single NPI to operate in multiple perceptually diverse environments with distinct affordances. By learning to compose lower-level programs to express higher-level programs, NPI reduces sample complexity ...

  7. The Mathematica programmer

    Maeder, Roman E

    1994-01-01

    The Mathematica Programmer covers the fundamental programming paradigms and applications of programming languages. This book is organized into two parts encompassing 10 chapters. Part 1 begins with an overview of the programming paradigms. This part also treats abstract data types, polymorphism and message passing, object-oriented programming, and relational databases. Part 2 looks into the practical aspects of programming languages, including in lists and power series, fractal curves, and minimal surfaces.This book will prove useful to mathematicians and computer scientists.

  8. Programmable matter by folding

    Hawkes, E.; An, B.; Benbernou, N. M.; Tanaka, H.; Kim, S.; Demaine, E. D.; Rus, D.; Wood, R. J.

    2010-01-01

    Programmable matter is a material whose properties can be programmed to achieve specific shapes or stiffnesses upon command. This concept requires constituent elements to interact and rearrange intelligently in order to meet the goal. This paper considers achieving programmable sheets that can form themselves in different shapes autonomously by folding. Past approaches to creating transforming machines have been limited by the small feature sizes, the large number of components, and the associated complexity of communication among the units. We seek to mitigate these difficulties through the unique concept of self-folding origami with universal crease patterns. This approach exploits a single sheet composed of interconnected triangular sections. The sheet is able to fold into a set of predetermined shapes using embedded actuation. To implement this self-folding origami concept, we have developed a scalable end-to-end planning and fabrication process. Given a set of desired objects, the system computes an optimized design for a single sheet and multiple controllers to achieve each of the desired objects. The material, called programmable matter by folding, is an example of a system capable of achieving multiple shapes for multiple functions. PMID:20616049

  9. Programmable Quantitative DNA Nanothermometers.

    Gareau, David; Desrosiers, Arnaud; Vallée-Bélisle, Alexis

    2016-07-13

    Developing molecules, switches, probes or nanomaterials that are able to respond to specific temperature changes should prove of utility for several applications in nanotechnology. Here, we describe bioinspired strategies to design DNA thermoswitches with programmable linear response ranges that can provide either a precise ultrasensitive response over a desired, small temperature interval (±0.05 °C) or an extended linear response over a wide temperature range (e.g., from 25 to 90 °C). Using structural modifications or inexpensive DNA stabilizers, we show that we can tune the transition midpoints of DNA thermometers from 30 to 85 °C. Using multimeric switch architectures, we are able to create ultrasensitive thermometers that display large quantitative fluorescence gains within small temperature variation (e.g., > 700% over 10 °C). Using a combination of thermoswitches of different stabilities or a mix of stabilizers of various strengths, we can create extended thermometers that respond linearly up to 50 °C in temperature range. Here, we demonstrate the reversibility, robustness, and efficiency of these programmable DNA thermometers by monitoring temperature change inside individual wells during polymerase chain reactions. We discuss the potential applications of these programmable DNA thermoswitches in various nanotechnology fields including cell imaging, nanofluidics, nanomedecine, nanoelectronics, nanomaterial, and synthetic biology. PMID:27058370

  10. A new video programme

    CERN video productions

    2011-01-01

    "What's new @ CERN?", a new monthly video programme, will be broadcast on the Monday of every month on webcast.cern.ch. Aimed at the general public, the programme will cover the latest CERN news, with guests and explanatory features. Tune in on Monday 3 October at 4 pm (CET) to see the programme in English, and then at 4:20 pm (CET) for the French version.   var flash_video_player=get_video_player_path(); insert_player_for_external('Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-0753-kbps-640x360-25-fps-audio-64-kbps-44-kHz-stereo', 'mms://mediastream.cern.ch/MediaArchive/Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-Multirate-200-to-753-kbps-640x360-25-fps.wmv', 'false', 480, 360, 'https://mediastream.cern.ch/MediaArchive/Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-posterframe-640x360-at-10-percent.jpg', '1383406', true, 'Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-0600-kbps-maxH-360-25-fps-...

  11. Quality control programme for radiotherapy

    A 3 years pilot programme started in January 2000 with 33 philanthropic cancer institutions that provides medical services to 60% of the patients from the national social security system. Brazil has today 161 radiotherapy services (144 operating with megavoltage equipment). These 33 institutions are distributed over 19 Brazilian states. The aim of this programme is: To create conditions to allow the participants to apply the radiotherapy with quality and efficacy; To promote up dating courses for the physicians, physicists and technicians of these 33 Institutions. With the following objectives: To recommend dosimetric and radiological protection procedures in order to guarantee the tumor prescribed dose and safe working conditions; To help in establishing and implementing these procedures. The main activities are: local quality control evaluations, postal TLD audits in reference conditions, postal TLD audits in off axis conditions and training. The local quality control program has already evaluated 22 institutions with 43 machines (25 Co-60 and 18 linear accelerators). In these visits we perform dosimetric, electrical, mechanical and safety tests. As foreseen, we found more problems among the old Co-60 machines i.e., field flatness, size, symmetry and relative output factors; lasers positioning system alignment; optical distance indicator; radiation and light field coincidence; optical and mechanical distance indicators agreement, than among the linear accelerators i.e., field flatness and size; lasers positioning system alignment; tray interlocking and wedge filter factors

  12. 2001 - 2002 ACADEMIC TRAINING PROGRAMME

    Academic Training; Tel. 73127

    2001-01-01

    1ST TERM 1ST OCTOBER - 23 NOVEMBER 2001 LECTURE SERIES FOR POSTGRADUATE STUDENTS The Autumn term of the Academic Training Programme is about to start. As usual, the first term includes lectures primarily dedicated to Post-graduate students. These are meant to help students complement the courses available from their home Universities with lectures on topics close to CERN activities. The lectures are nevertheless open to all CERN staff, and in particular to young Fellows. This year's series include courses on Accelerator Physics, on Field Theory, and on Symmetry Breaking Phenomena in Physics. The course on Accelerators by Dr. Wilson has been a regular feature on the Academic Training programme for many previous editions. This year, the course will be updated to include new sections on Colliders and on future facilities such as the Neutrino Factory. A good introduction to this very successful course can be found in the previous version of these lectures, available from the Web Lecture Archive Project: http://w...

  13. Sellafield Decommissioning Programme - Update and Lessons Learned

    Lutwyche, P. R.; Challinor, S. F.

    2003-02-24

    The Sellafield site in North West England has over 240 active facilities covering the full nuclear cycle from fuel manufacture through generation, reprocessing and waste treatment. The Sellafield decommissioning programme was formally initiated in the mid 1980s though several plants had been decommissioned prior to this primarily to create space for other plants. Since the initiation of the programme 7 plants have been completely decommissioned, significant progress has been made in a further 16 and a total of 56 major project phases have been completed. This programme update will explain the decommissioning arrangements and strategies and illustrate the progress made on a number of the plants including the Windscale Pile Chimneys, the first reprocessing plan and plutonium plants. These present a range of different challenges and requiring approaches from fully hands on to fully remote. Some of the key lessons learned will be highlighted.

  14. FFUSION research programme 1993-1998. Final report of the Finnish fusion research programme

    Karttunen, S.; Heikkinen, J.; Korhonen, R. [VTT Energy, Espoo (Finland)] [and others

    1998-12-31

    This report summarizes the results of the Fusion Energy Research Programme, FFUSION, during the period 1993-1998. After the planning phase the programme started in 1994, and later in March 1995 the FFUSION Programme was integrated into the EU Fusion Programme and the Association Euratom-Tekes was established. Research areas in the FFUSION Programme are (1) fusion physics and plasma engineering, (2) fusion reactor materials and (3) remote handling systems. In all research areas industry is involved. Recently, a project on environmental aspects of fusion and other future energy systems started as a part of the socio-economic research (SERF) in the Euratom Fusion Programme. A crucial component of the FFUSION programme is the close collaboration between VTT Research Institutes, universities and Finnish industry. This collaboration has guaranteed dynamic and versatile research teams, which are large enough to tackle challenging research and development projects. Regarding industrial fusion R and D activities, the major step was the membership of Imatran Voima Oy in the EFET Consortium (European Fusion Engineering and Technology), which further strengthened the position of industry in the engineering design activities of ITER. The number of FFUSION research projects was 66. In addition, there were 32 industrial R and D projects. The total cost of the FFUSION Programme in 1993-1998 amounted to FIM 54 million in research at VTT and universities and an additional FIM 21 million for R and D in Finnish industry. The main part of the funding was provided by Tekes, 36%. Since 1995, yearly Euratom funding has exceeded 25%. The FFUSION research teams have played an active role in the European Programme, receiving excellent recognition from the European partners. Theoretical and computational fusion physics has been at a high scientific level and the group collaborates with the leading experimental laboratories in Europe. Fusion technology is focused on reactor materials, joining

  15. FFUSION research programme 1993-1998. Final report of the Finnish fusion research programme

    This report summarizes the results of the Fusion Energy Research Programme, FFUSION, during the period 1993-1998. After the planning phase the programme started in 1994, and later in March 1995 the FFUSION Programme was integrated into the EU Fusion Programme and the Association Euratom-Tekes was established. Research areas in the FFUSION Programme are (1) fusion physics and plasma engineering, (2) fusion reactor materials and (3) remote handling systems. In all research areas industry is involved. Recently, a project on environmental aspects of fusion and other future energy systems started as a part of the socio-economic research (SERF) in the Euratom Fusion Programme. A crucial component of the FFUSION programme is the close collaboration between VTT Research Institutes, universities and Finnish industry. This collaboration has guaranteed dynamic and versatile research teams, which are large enough to tackle challenging research and development projects. Regarding industrial fusion R and D activities, the major step was the membership of Imatran Voima Oy in the EFET Consortium (European Fusion Engineering and Technology), which further strengthened the position of industry in the engineering design activities of ITER. The number of FFUSION research projects was 66. In addition, there were 32 industrial R and D projects. The total cost of the FFUSION Programme in 1993-1998 amounted to FIM 54 million in research at VTT and universities and an additional FIM 21 million for R and D in Finnish industry. The main part of the funding was provided by Tekes, 36%. Since 1995, yearly Euratom funding has exceeded 25%. The FFUSION research teams have played an active role in the European Programme, receiving excellent recognition from the European partners. Theoretical and computational fusion physics has been at a high scientific level and the group collaborates with the leading experimental laboratories in Europe. Fusion technology is focused on reactor materials, joining

  16. When kissing (disease) counts

    Van Roosbroeck, Katrien; Calin, George A.

    2016-01-01

    In this issue of Blood, Kanakry et al analyzed Epstein-Barr virus (EBV) DNA expression in peripheral blood cellular compartments from 2146 patients with various malignancies and found that cell-free plasma EBV DNA was a better marker of EBV+ disease than EBV DNA from peripheral blood mononuclear cells (PBMCs).1

  17. Finnish Research Programme on Nuclear Waste Management (KYT). Framework Programme for 2002-2005

    The new Finnish research programme on nuclear waste management (KYT) will be conducted in 2002 - 2005. This framework programme describes the starting point, the basic aims and the organisation of the research programme. The starting point of the KYT programme is derived from the present state and future challenges of Finnish nuclear waste management. The research programme is funded mainly by the Ministry of Trade and Industry (KTM), the Radiation and Nuclear Safety Authority (STUK), Posiva Oy, Fortum Oyj, Teollisuuden Voima Oy (TVO), and the National Technology Agency (Tekes). As both regulators and implementors are involved, the research programme concentrates on neutral research topics that must be studied in any case. Methods and tools for experimental and theoretical studies fall in this category. State of the art -reviews on relevant topics also create national know-how. Topics that directly belong to licensing activities of nuclear waste management are excluded from the research programme. KYT carries out technical studies that increase national know-how in the area of nuclear waste management. The aim is to maintain and develop basic expertise needed in the operations derived from the national nuclear waste management plan. The studies have been divided into strategic studies and studies enhancing the long-term safety of spent nuclear fuel disposal. Strategic studies support the overall feasibility of Finnish nuclear waste management. These studies include basic options and overall safety principles related to nuclear fuel cycle and nuclear waste management. In addition, general cost estimates as well as general safety considerations related to transportations, low- and medium level wastes, and decommissioning are included in strategic studies. Studies supporting the long-term safety of spent fuel disposal include issues related to performance assessment methodology, release of radionuclides from the repository, behaviour of bedrock and groundwater

  18. CASINDO Programme Summary Report

    Van der Linden, N.; Smekens, K.; Bole-Rentel, T.; Saidi, R. [Unit ECN Policy Studies, Energy research Centre of the Netherlands ECN, Petten (Netherlands); Wijnker, M. [Eindhoven University of Technology TUE, Eindhoven (Netherlands); Kamphuis, E. [ETC Netherlands, Leusden (Netherlands); Winarno, Oetomo Tri [Institute of Technology, Bandung (Indonesia); Permana, Iman [Technical Education Development Centre, Bandung (Indonesia)

    2012-06-15

    The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. CASINDO stands for Capacity development and strenghtening for energy policy formulation adn implementation of sustainable energy projects in Indonesia.

  19. Accident prevention programme

    This study by the Steel Industry Safety and Health Commission was made within the context of the application by undertakings of the principles of accident and disease prevention previously adopted by the said Commission. It puts forward recommendations for the effective and gradual implementation of a programme of action on occupational health and safety in the various departments of an undertaking and in the undertaking as a whole. The methods proposed in this study are likely to be of interest to all undertakings in the metallurgical industry and other industrial sectors

  20. Fusion technology programme

    In the current Fusion Technology Programme of the European Community the KfK association is working at present on 16 R and D contracts. Most of the work is strongly oriented towards the Next European Torus. Direct support to NET is given by three KfK delegates being member of the NET study group. In addition to the R and D contracts the association is working on 11 NET study contracts. Though KfK contributes to all areas defined in fusion technology, the main emphasis is put on superconducting magnet and breeding blanket development. Other important fields are tritium technology, materials research, and remote handling. (orig./GG)

  1. Research and training programmes

    Daksha Patel

    2007-03-01

    Full Text Available Research is defined in the Oxford English Dictionary as “a systematic investigation and study of materials and sources in order to establish facts and reach new conclusions.”Research is embedded in the curricula of most postgraduate training programmes; students are expected to complete some form of original work towards a dissertation. This often evokes a range of reactions: “What is the purpose of this exercise? Why do I have to do research when I just want to do a job? Shouldn’t research rather be left to experts? I can’t do the course; I have no research background!”

  2. Research and training programmes

    Daksha Patel

    2007-01-01

    Research is defined in the Oxford English Dictionary as “a systematic investigation and study of materials and sources in order to establish facts and reach new conclusions.”Research is embedded in the curricula of most postgraduate training programmes; students are expected to complete some form of original work towards a dissertation. This often evokes a range of reactions: “What is the purpose of this exercise? Why do I have to do research when I just want to do a job? Shouldn’t research r...

  3. Programmable ferroelectric tunnel memristor

    Andy eQuindeau; Dietrich eHesse; Marin eAlexe

    2014-01-01

    We report an analogously programmable memristor based on genuine electronic resistive switching combining ferroelectric switching and electron tunneling. The tunnel current through an 8 unit cell thick epitaxial Pb(Zr[0.2]Ti[0.8])O[3] film sandwiched between La[0.7]Sr[0.3]MnO[3] and cobalt electrodes obeys the Kolmogorov-Avrami-Ishibashi model for bidimensional growth with a characteristic switching time in the order of 10^-7 seconds. The analytical description of switching kinetics allows us...

  4. The community programme revisited

    Anne Gray

    1999-01-01

    This paper examines the lessons for the New Deal era of some older strands in UK and European labour market measures; the Community Programme of the 1980s and the experience of “entreprises d'insertion in France, Spain and the Netherlands. It considers whether the institutional infrastructure of the New Deal is appropriate for the realisation of "intermediate labour marketsâ€. This raises some further questions; whether ILMs are about creating employment or merely redistributing it, and whe...

  5. Progress in Programmable Logic

    Jozef Cuntala

    2004-01-01

    Full Text Available Programmable logic devices (PLD are situated on important place among microelectronic components thanks to the continuing technological development of semiconductor components, due to new architectures and new approaches to digital systems design. Software design of various complicated digital systems becomes advantageous article of many firms. The Department of Electronics and Electrotechnology pays pemanent attention to mentioned components in application field. The collective of authors wants in this article point out on possibilities of design of digital system using the PLD. The paper plan contains the following basic parts: Technological aspects that influence development of configurable logic devices, Methodology od design and implementation and Flexibility of PLD interface.

  6. A programmable Fortran preprocessor

    Rosing, M.

    1995-06-01

    A programmable Fortran preprocessor is described. It allows users to define compile time operations that can examine and modify the source tree before it is compiled with a traditional compiler. This intermediate step allows the definition of routines and operations that adapt to the context in which they are used. Context sensitive operations increase the flexibility of abstractions that can be built without degrading efficiency, as compared to using traditional run time based abstractions such as libraries or objects. The preprocessor is described briefly along with an example of how it is used to add CMFortran array operations to Fortran77. Other preprocessors that have been implemented are also briefly described.

  7. Programme Biology - Health protection

    The scientific results for 1975, of the five-year Biology-Health Protection programme adopted in 1971, are presented in two volumes. In volume one, Research in Radiation Protection are developed exclusively, including the following topics: measurement and interpretation of radiation (dosimetry); transfer of radioactive nuclides in the constituents of the environment; hereditary effects of radiation; short-term effects (acute irradiation syndrome and its treatment); long-term effects and toxicology of radioactive elements. In volume, two Research on applications in Agriculture and Medicine are developed. It includes: mutagenesis; soil-plant relations; radiation analysis; food conservation; cell culture; radioentomology. Research on applications in Medicine include: Nuclear Medicine and Neutron Dosimetry

  8. Personal goals, group performance and ‘social’ networks: participants’ negotiation of virtual and embodied relationships in the ‘Workplace Challenge’ physical activity programme

    Evans, Adam Brian; Carter, Alice; Middleton, Geoff;

    2016-01-01

    encourage workplace-based teams to engage in physical activity by self-recording their activity over an eight-week period. Points were awarded for activity completed and a peer-challenge facility was promoted via online league tables, prizes and the opportunity to ‘challenge’ other users. Semi...... professional I–We identities, whereas virtual networks sometimes highlighted participants’ isolation. Moreover, emphasis upon competition within and between teams caused some participants to question their performance. Often, competition motivated engagement. For less active participants, constant comparison...

  9. Nuclear power programme planning: An integrated approach

    The International Atomic Energy Agency (IAEA) has published material on different policy considerations in the introduction of nuclear power, primarily addressed to top level decision makers in government and industry in Member States. Several Member States and experts recommended to the IAEA to address the aspects of an integrated approach to nuclear power programme planning and to serve as guidance to those countries wishing to embark on a nuclear power programme. As a follow-up, the present publication is primarily intended to serve as guidance for executives and managers in Member States in planning for possible introduction of nuclear power plants in their electricity generating systems. Nuclear power programme planning, as dealt with in this publication, includes all activities that need to be carried out up to a well-founded decision to proceed with a project feasibility study. Project implementation beyond this decision is not in the scope of this publication. Although it is possible to use nuclear energy as a heat source for industrial processes, desalination and other heat applications, it is assumed in this publication that the planning is aimed towards nuclear power for electricity generation. Much of the information given would, however, also be relevant for planning of nuclear reactors for heat production. The publication was prepared within the framework of the IAEA programme on nuclear power planning, implementation and performance as a joint activity of the Nuclear Power Engineering Section and the Planning and Economic Studies Section (Division of Nuclear Power)

  10. RDandD Programme 2010. Programme for research, development and demonstration of methods for the management and disposal of nuclear waste

    2010-09-15

    RDandD Programme 2010 presents SKB's plans for research, development and demonstration during the period 2011-2016. SKB's activities are divided into two main areas: the programme for low- and intermediate-level waste (the LILW Programme) and the Nuclear Fuel Programme. Operation of the existing facilities takes place within the Operational Process. RDandD Programme 2010 consists of five parts: Part I Overall plan of action Part II The LILW Programme Part III The Nuclear Fuel Programme Part IV Research for assessment of long-term safety Part V Social science research RDandD Programme 2007 was mainly focused on development of technology to realize the final repository for spent nuclear fuel. The efforts described were aimed at gaining a greater knowledge of long-term safety and compiling technical supporting documentation for applications under the Nuclear Activities Act for the final repository for spent nuclear fuel and under the Environmental Code for the final repository system. Many important results from these efforts are reported in this programme. The integrated account of the results will be presented in applications submitted in early 2011. The regulatory review of RDandD Programme 2007 and its supplement called for clarifications of plans and programmes for the final repository for short-lived radioactive waste, SFR, and the final repository for long-lived waste, SFL. This RDandD Programme describes these plans more clearly

  11. RDandD Programme 2010. Programme for research, development and demonstration of methods for the management and disposal of nuclear waste

    RDandD Programme 2010 presents SKB's plans for research, development and demonstration during the period 2011-2016. SKB's activities are divided into two main areas: the programme for low- and intermediate-level waste (the LILW Programme) and the Nuclear Fuel Programme. Operation of the existing facilities takes place within the Operational Process. RDandD Programme 2010 consists of five parts: Part I Overall plan of action Part II The LILW Programme Part III The Nuclear Fuel Programme Part IV Research for assessment of long-term safety Part V Social science research RDandD Programme 2007 was mainly focused on development of technology to realize the final repository for spent nuclear fuel. The efforts described were aimed at gaining a greater knowledge of long-term safety and compiling technical supporting documentation for applications under the Nuclear Activities Act for the final repository for spent nuclear fuel and under the Environmental Code for the final repository system. Many important results from these efforts are reported in this programme. The integrated account of the results will be presented in applications submitted in early 2011. The regulatory review of RDandD Programme 2007 and its supplement called for clarifications of plans and programmes for the final repository for short-lived radioactive waste, SFR, and the final repository for long-lived waste, SFL. This RDandD Programme describes these plans more clearly

  12. Fast reactor programme

    This progress report summarizes the fast reactor research carried out by ECN during the period covering the year 1980. This research is mainly concerned with the cores of sodium-cooled breeders, in particular the SNR-300, and its related safety aspects. It comprises six items: A programme to determine relevant nuclear data of fission- and corrosion-products; A fuel performance programme comprising in-pile cladding failure experiments and a study of the consequences of loss-of-cooling and overpower; Basic research on fuel; Investigation of the changes in the mechanical properties of austenitic stainless steel DIN 1.4948 due to fast neutron doses, this material has been used in the manufacture of the reactor vessel and its internal components; Study of aerosols which could be formed at the time of a fast reactor accident and their progressive behaviour on leaking through cracks in the concrete containment; Studies on heat transfer in a sodium-cooled fast reactor core. As fast breeders operate at high power densities, an accurate knowledge of the heat transfer phenomena under single-phase and two-phase conditions is sought. (Auth.)

  13. Reactor Physics Programme

    The Reactor Physics and Department of SCK-CEN offers expertise in various areas of reactor physics, in particular in neutronics calculations, reactor dosimetry, reactor operation, reactor safety and control and non-destructive analysis on reactor fuel. This expertise is applied within the Reactor Physics and MYRRHA Research Department's own research projects in the VENUS critical facility, in the BR1 reactor and in the MYRRHA project (this project aims at designing a prototype Accelerator Driven System). Available expertise is also used in programmes external to the Department such as the reactor pressure steel vessel programme, the BR2 reactor dosimetry, and the preparation and interpretation of irradiation experiments. Progress and achievements in 1999 in the following areas are reported on: (1) investigations on the use of military plutonium in commercial power reactors; (2) neutron and gamma calculations performed for BR-2 and for other reactors; (3) the updating of neutron and gamma cross-section libraries; (4) the implementation of reactor codes; (6) the management of the UNIX workstations; and (6) fuel cycle studies

  14. Accelerator programme at CAT

    The Accelerator Programme at the Centre for Advanced Technology (CAT), Indore, has very broad based concept under which all types of accelerators are to be taken up for design and fabrication. This centre will be housing a wide variety of accelerators to serve as a common facility for the universities, national laboratories in addition to laboratories under the Department of Atomic Energy. In the first phase of the programme, a series of electron accelerators are designed and fabricated. They are synchrotron radiation sources of 450 MeV (INDUS-I) and of 2 GeV (INDUS-II), microtron upto energy of 20 MeV, linear accelerator upto 20 MeV, and DC Accelerator for industrial irradiation upto 750 KeV and 20 KW. A proton accelerator of 300 MeV with 20 MeV linac injector is also designed. CAT is also developing a strong base for support technologies like ultra high vacuum, radio frequency and microwaves, DC pulsed and superconducting magnets, power supplies and controls etc. These technologies are very useful for other industrial applications also. To develop user groups to utilise INDUS-II synchrotron radiation source, a batch production of rotating Anode X-ray generators with power supplies has been initiated. So also, the sputter ion pumps, electron guns, turbo molecular pumps are brought into batch production. (author)

  15. PREPARATION FOR RETIREMENT PROGRAMME

    Human Resources Division

    2001-01-01

    27 March 2001 from 2.00 p.m. to 5.30 p.m. 28 March 2001 from 2.00 p.m. to 5.30 p.m. 29 March 2001 from 2.00 p.m. to 5.30 p.m. 30 March 2001 from 2.00 p.m. to 4.45 p.m. Auditorium (Main Building) After the success of the preparation seminars held in recent years, it has been decided that the programme should continue. The forthcoming seminar has been prepared in close collaboration with the CERN Pensioners' Association. The programme will be organised over several half-day sessions. Once again this year, a special session will be devoted to the 10th revision of the Swiss state pension scheme, the 'AVS' (Assurance-Vieillesse et Survivants), and the consequences for international civil servants. A talk will be given by Mrs Danièle Siebold, Director of the Caisse Cantonale Genevoise de Compensation, aimed mainly at those residing in or intending to move to Switzerland, or who worked in Switzerland before joining CERN. To enable Mrs Siebold to respond to your concerns as effectively as possible, please ...

  16. Nuclear programme in Indonesia

    Implementation of the energy policy covers several aspects such as issuance of regulations, standards, energy pricing incentives and disincentives, and the application of appropriate technologies. The policies and implementation of the technologies can fully be supported by the use of nuclear technology, especially toward the now popular issue concerning the environment. In view of these policies and the need to implement these policies. i.e. for the diversification of energy and environmental concern, the Department of Mines and Energy has established an Indonesian Energy Coordination Board (BAKOREN). This board has realised the importance of considering nuclear as a source of energy, which has led to a decision in September 1989, for The National Atomic Energy Agency (BATAN) to conduct a feasibility study to introduce nuclear power plants in Indonesia. The establishment of an authority for the construction and operation of Nuclear Power Plants in Indonesia, which is primarily related to the safe and efficient operation of nuclear power plants, must also be prepared. This authority is still under considerations by the Indonesian Government. In implementing the Indonesia Nuclear Programme, it is important that cooperation exists among countries of the world, Korea, in this respect, as learning from experiences of other countries are very necessary to plan for a successful Nuclear Programme

  17. Energy technology programmes 1993-1998. Evaluation report

    1999-09-01

    In the late 1980s Finland`s Ministry of Trade and Industry (KTM) initiated a series of research and development (R and D) programmes in the field of energy technology. Subsequently, in 1993, it launched a further suite of eleven Energy Technology Programmes scheduled to run over the period 1993-1998. Aimed at the development of efficient and environmentally sound energy technologies intended to be competitive in the international marketplace, the programmes sought to involve the research, industrial and public sectors in some FIM 1.2 billion of research and development activity. The technology areas spanned: Combustion and gasification techniques Bioenergy, Advanced energy systems and technologies (e.g. wind, solar energy), Fusion, Energy and environmental technology, Energy and the environment in transportation, Energy use in buildings, Energy in steel and metal production, Energy in paper and board production, District heating, Electricity distribution automation. In early 1995, the Technology Development Centre of Finland (Tekes) assumed responsibility for the funding, management and administration of the programmes. As the final year of activities began, Tekes commissioned Technopolis to assemble a team to conduct a major review of all eleven programmes over the course of 1998. The broad aim of the exercise was to review the experience of the eleven technology R and D programmes and to make suggestions for the future. In particular, the intention was to cover a number of distinct levels. Most important were the Programme and Portfolio levels. At the individual Programme level, the review was to comment on the relevance, calibre and impact of programmes, concentrating in particular on the following: Relevance - were programme and project level goals in line with Finnish interests and comparable agendas in other countries; Efficiency - how well were the programmes implemented and managed; Quality - how did the scientific and technological quality of the work

  18. CAMAC modular programmable function generator

    A CAMAC modular programmable function generator has been developed. The device contains a 1024 word by 12-bit memory, a 12-bit digital-to-analog converter with a 600 ns settling time, an 18-bit programmable frequency register, and two programmable trigger output registers. The trigger registers can produce programmed output logic transitions at various (binary) points in the output function curve, and are used to synchronize various other data acquisition devices with the function curve

  19. The effect a of community-based social marketing campaign on recruitment and retention of low-income groups into physical activity programmes - a controlled before-and-after study

    2012-01-01

    Background The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These conditions are most prevalent in low-income groups where physical activity levels are consistently lower. Social marketing is the government’s recommended approach to promoting physical activity but evidence of its effectiveness is limited. The purpose of this study was to examine the effect of a social marketing campaign on the monthly recruitment, attendance and retention levels at a community-based physical activity programme in a low income area. Methods A six-month social marketing campaign was designed and delivered in a highly-deprived suburban neighbourhood. Analysis of variance was used to assess effects on recruitment and attendance. χ2 tests of independence were used to compare dropouts and adherers and effectiveness of recruitment mechanisms. Percentages were used to compare adherence rates at intervention, pre-existing sessions in the intervention area and control area sessions. Results Attendance data were collected weekly and presented and analysed monthly to provide a view of changing participation over the six month intervention period, as compared to attendance at pre-existing sessions in the intervention area and in a control area. Recruitment into intervention sessions was significantly greater than into pre-existing and control area sessions in Month 1 (18.13v1.04 p = .007, 18.13v.30 p=.005), Month 5 (3.45v.84 p=.007, 3.45v.30 pmarketing techniques (posters/outdoor banners/flyers) had the greatest influence on recruitment compared to word of mouth communication (84.5%v15.5%). In months five and six word of mouth influenced 57.5% of new recruits. Conclusions Direct comparisons with other programmes were difficult due to a lack of standard definitions of recruitment and adherence and limited reporting of findings. However when compared to pre-existing sessions and sessions delivered in a control area

  20. The effect a of community-based social marketing campaign on recruitment and retention of low-income groups into physical activity programmes - a controlled before-and-after study

    Withall Janet

    2012-10-01

    Full Text Available Abstract Background The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These conditions are most prevalent in low-income groups where physical activity levels are consistently lower. Social marketing is the government’s recommended approach to promoting physical activity but evidence of its effectiveness is limited. The purpose of this study was to examine the effect of a social marketing campaign on the monthly recruitment, attendance and retention levels at a community-based physical activity programme in a low income area. Methods A six-month social marketing campaign was designed and delivered in a highly-deprived suburban neighbourhood. Analysis of variance was used to assess effects on recruitment and attendance. χ2 tests of independence were used to compare dropouts and adherers and effectiveness of recruitment mechanisms. Percentages were used to compare adherence rates at intervention, pre-existing sessions in the intervention area and control area sessions. Results Attendance data were collected weekly and presented and analysed monthly to provide a view of changing participation over the six month intervention period, as compared to attendance at pre-existing sessions in the intervention area and in a control area. Recruitment into intervention sessions was significantly greater than into pre-existing and control area sessions in Month 1 (18.13v1.04 p = .007, 18.13v.30 p=.005, Month 5 (3.45v.84 p=.007, 3.45v.30 p Conclusions Direct comparisons with other programmes were difficult due to a lack of standard definitions of recruitment and adherence and limited reporting of findings. However when compared to pre-existing sessions and sessions delivered in a control area, monthly attendance patterns indicated that a reasonably well funded social marketing campaign increased recruitment into exercise sessions, maintained good levels of attendance and reasonable levels

  1. 'Mother of all Sport’: an evaluation of a women’s community sports programme

    Mahedy, Tracy

    2015-01-01

    peer-reviewed The purpose of the ‘Mother of all Sport’ programme is to investigate the effect of a physical activity programme on women in disadvantaged communities and evaluate whether this type of programme can encourage women to participate in physical activity in their local community. This research project subsequently examines women's perception of sport and physical activity and explores whether a community approach to sport and physical activity can change women's vi...

  2. ‘Mother of all sport’: an evaluation of a women’s community sports programme

    Mahedy, Tracy; MacPhail, Ann

    2015-01-01

    peer-reviewed The purpose of the ‘Mother of all Sport’ programme is to investigate the effect of a physical activity programme on women in disadvantaged communities and evaluate whether this type of programme can encourage women to participate in physical activity in their local community. This research project subsequently examines women's perception of sport and physical activity and explores whether a community approach to sport and physical activity can change women's vi...

  3. What promotes sustainability in Safe Community programmes?

    Lindqvist Kent

    2009-01-01

    . Increased relational resources facilitated the transfer of information. A regular flow of information to policy-makers, residents, and staff was needed in order to integrate safety programmes into routines. Adopting a bottom-up approach requires that informal and ad hoc activities in information management be replaced by formalized, organizationally sanctioned routines. In contrast to injury prevention, which focuses on technical solutions, safety promotion tries to influence attitudes. Collaboration with the media was an area that could be improved.

  4. Student responses to the introduction of case-based learning and practical activities into a theoretical obstetrics and gynaecology teaching programme

    de Toledo Sérgio; Assis Paulo; Marcellini Cláudio; Massonetto Júlio

    2004-01-01

    Abstract Background The fourth-year Obstetrics and Gynaecology course at our institution had previously been taught using theory classes alone. A new teaching model was introduced to provide a better link with professional practice. We wished to evaluate the impact of the introduction of case discussions and other practical activities upon students' perceptions of the learning process. Methods Small-group discussions of cases and practical activities were introduced for the teaching of a four...

  5. The ONTARGET trial programme

    Unger, Thomas; Kintscher, Ulrich; Kappert, Kai;

    2009-01-01

    The ONTARGET trial programme tested the effects of the angiotensin AT1 receptor blocker (ARB), telmisartan, alone or in combination with the angiotensin converting enzyme (ACE) inhibitor, ramipril, in more than 25.000 patients at high cardiovascular risk including diabetes on a combined endpoint....... Telmisartan thus proved to be the first and so far the only representative of the ARB class that can be used as an alternative to the "gold standard" ACE-inhibitor, ramipril, in patients at high cardiovascular risk with or without hypertension. © 2009 Bentham Science Publishers Ltd....... consisting of cardiovascular death, non-fatal stroke or myocardial infarction and hospitalisation for congestive heart failure. Patient selection and study procedures followed the previous HOPE trial. In the parallel TRANSCEND study, nearly 6.000 patients, all intolerant to ACE inhibition, were subjected...

  6. Country programme review Bangladesh

    A five-expert mission was organized from 21-26 August 1993 and this document reflects the findings and recommendations of the team. Intensive contacts with heads of institutions, scientists and decision making persons in various sectors in the country were co-ordinated by the Bangladesh Atomic Energy Commission. The terms of reference of the mission were: To assess the on-going TC projects; to assist the Bangladesh nationals to finalize the formulation of the new requests for 1995-96 TC programme and to establish priority areas with regard to the introduction of national projects involving accelerated technological transfer in order to catalyze national development plans in specific areas; to examine institutional framework suitable for the introduction of these priority nuclear techniques

  7. Programmable ferroelectric tunnel memristor

    Andy eQuindeau

    2014-02-01

    Full Text Available We report an analogously programmable memristor based on genuine electronic resistive switching combining ferroelectric switching and electron tunneling. The tunnel current through an 8 unit cell thick epitaxial Pb(Zr[0.2]Ti[0.8]O[3] film sandwiched between La[0.7]Sr[0.3]MnO[3] and cobalt electrodes obeys the Kolmogorov-Avrami-Ishibashi model for bidimensional growth with a characteristic switching time in the order of 10^-7 seconds. The analytical description of switching kinetics allows us to develop a characteristic transfer function that has only one parameter viz. the characteristic switching time and fully predicts the resistive states of this type of memristor.

  8. Programmability of nanowire networks

    Bellew, A. T.; Bell, A. P.; McCarthy, E. K.; Fairfield, J. A.; Boland, J. J.

    2014-07-01

    Electrical connectivity in networks of nanoscale junctions must be better understood if nanowire devices are to be scaled up from single wires to functional material systems. We show that the natural connectivity behaviour found in random nanowire networks presents a new paradigm for creating multi-functional, programmable materials. In devices made from networks of Ni/NiO core-shell nanowires at different length scales, we discover the emergence of distinct behavioural regimes when networks are electrically stressed. We show that a small network, with few nanowire-nanowire junctions, acts as a unipolar resistive switch, demonstrating very high ON/OFF current ratios (>105). However, large networks of nanowires distribute an applied bias across a large number of junctions, and thus respond not by switching but instead by evolving connectivity. We demonstrate that these emergent properties lead to fault-tolerant materials whose resistance may be tuned, and which are capable of adaptively reconfiguring under stress. By combining these two behavioural regimes, we demonstrate that the same nanowire network may be programmed to act both as a metallic interconnect, and a resistive switch device with high ON/OFF ratio. These results enable the fabrication of programmable, multi-functional materials from random nanowire networks.Electrical connectivity in networks of nanoscale junctions must be better understood if nanowire devices are to be scaled up from single wires to functional material systems. We show that the natural connectivity behaviour found in random nanowire networks presents a new paradigm for creating multi-functional, programmable materials. In devices made from networks of Ni/NiO core-shell nanowires at different length scales, we discover the emergence of distinct behavioural regimes when networks are electrically stressed. We show that a small network, with few nanowire-nanowire junctions, acts as a unipolar resistive switch, demonstrating very high ON

  9. Multinational design approval programme

    The licensing of new nuclear power facilities is likely to pose many challenges to national regulatory organizations. The majority of nuclear power plants to be built around the world in the next 15 years will likely be limited to a small number of relatively standardized designs, purchased from a limited number of multinational corporations. Such standardization creates an opportunity to leverage the resources and knowledge of the national regulatory authorities who will be tasked with the review of the new reactor power plant designs. The Nuclear Regulatory Commission has developed an innovative proposal for a multinational design approval programme (MDAP). This paper describes the stages of the MDAP and the benefits that could be derived from its implementation. (author)

  10. Changes in activity of industrial enzyme preparations irradiated with sterilizing doses. Part of a coordinated programme on factors influencing the utilization of food irradiation process

    Experiments were carried out to investigate the efficacy of irradiation to sterilize enzyme preparations. Irradiation doses up to 25 kGy caused no changes in basic organoleptic properties of commercial rennin preparations. Dose rate (from 0.5 to 13.5 kGy/hr) has no influence on the changes in enzyme activity during the storage period of 3 months. Doses ranging from 8 to 12 kGy are sufficient to sterilize commercial enzyme preparations. Non-purified, crude rennin preparations appear to be more resistant to radiation than purified samples. Rennin preparations purified by dialysis and treated with 25 kGy resulted in a reduction of activity of 20%. The activity of preparations purified by gel filtration was reduced to 50% when treated with the same dose

  11. International Geological Correlation Programme (IGCP) /International Geoscience Programme (IGCP)

    WolfgangEder; MargaretePatzak

    2004-01-01

    Although many countries, especially from the developing world, share the most exciting geological features, geological structures and natural resources, research activities at various institutions are undertaken in isolation. The IGCP is unique as an international Programme that brings together several thousands of scientists from different disciplines, to stimulate dialogue and facilitate communication among

  12. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

    Bousquet, J; Farrell, J; Crooks, G; Hellings, P; Bel, E H; Bewick, M; Chavannes, N H; de Sousa, J Correia; Cruz, A A; Haahtela, T; Joos, G; Khaltaev, N; Malva, J; Muraro, A; Nogues, M; Palkonen, S; Pedersen, S; Robalo-Cordeiro, C; Samolinski, B; Strandberg, T; Valiulis, A; Yorgancioglu, A; Zuberbier, T; Bedbrook, A; Aberer, W; Adachi, M; Agusti, A; Akdis, C A; Akdis, M; Ankri, J; Alonso, A; Annesi-Maesano, I; Ansotegui, I J; Anto, J M; Arnavielhe, S; Arshad, H; Bai, C; Baiardini, I; Bachert, C; Baigenzhin, A K; Barbara, C; Bateman, E D; Beghé, B; Kheder, A Ben; Bennoor, K S; Benson, M; Bergmann, K C; Bieber, T; Bindslev-Jensen, C; Bjermer, L; Blain, H; Blasi, F; Boner, A L; Bonini, M; Bonini, S; Bosnic-Anticevitch, S; Boulet, L P; Bourret, R; Bousquet, P J; Braido, F; Briggs, A H; Brightling, C E; Brozek, J; Buhl, R; Burney, P G; Bush, A; Caballero-Fonseca, F; Caimmi, D; Calderon, M A; Calverley, P M; Camargos, P A M; Canonica, G W; Camuzat, T; Carlsen, K H; Carr, W; Carriazo, A; Casale, T; Cepeda Sarabia, A M; Chatzi, L; Chen, Y Z; Chiron, R; Chkhartishvili, E; Chuchalin, A G; Chung, K F; Ciprandi, G; Cirule, I; Cox, L; Costa, D J; Custovic, A; Dahl, R; Dahlen, S E; Darsow, U; De Carlo, G; De Blay, F; Dedeu, T; Deleanu, D; De Manuel Keenoy, E; Demoly, P; Denburg, J A; Devillier, P; Didier, A; Dinh-Xuan, A T; Djukanovic, R; Dokic, D; Douagui, H; Dray, G; Dubakiene, R; Durham, S R; Dykewicz, M S; El-Gamal, Y; Emuzyte, R; Fabbri, L M; Fletcher, M; Fiocchi, A; Fink Wagner, A; Fonseca, J; Fokkens, W J; Forastiere, F; Frith, P; Gaga, M; Gamkrelidze, A; Garces, J; Garcia-Aymerich, J; Gemicioğlu, B; Gereda, J E; González Diaz, S; Gotua, M; Grisle, I; Grouse, L; Gutter, Z; Guzmán, M A; Heaney, L G; Hellquist-Dahl, B; Henderson, D; Hendry, A; Heinrich, J; Heve, D; Horak, F; Hourihane, J O' B; Howarth, P; Humbert, M; Hyland, M E; Illario, M; Ivancevich, J C; Jardim, J R; Jares, E J; Jeandel, C; Jenkins, C; Johnston, S L; Jonquet, O; Julge, K; Jung, K S; Just, J; Kaidashev, I; Kaitov, M R; Kalayci, O; Kalyoncu, A F; Keil, T; Keith, P K; Klimek, L; Koffi N'Goran, B; Kolek, V; Koppelman, G H; Kowalski, M L; Kull, I; Kuna, P; Kvedariene, V; Lambrecht, B; Lau, S; Larenas-Linnemann, D; Laune, D; Le, L T T; Lieberman, P; Lipworth, B; Li, J; Lodrup Carlsen, K; Louis, R; MacNee, W; Magard, Y; Magnan, A; Mahboub, B; Mair, A; Majer, I; Makela, M J; Manning, P; Mara, S; Marshall, G D; Masjedi, M R; Matignon, P; Maurer, M; Mavale-Manuel, S; Melén, E; Melo-Gomes, E; Meltzer, E O; Menzies-Gow, A; Merk, H; Michel, J P; Miculinic, N; Mihaltan, F; Milenkovic, B; Mohammad, G M Y; Molimard, M; Momas, I; Montilla-Santana, A; Morais-Almeida, M; Morgan, M; Mösges, R; Mullol, J; Nafti, S; Namazova-Baranova, L; Naclerio, R; Neou, A; Neffen, H; Nekam, K; Niggemann, B; Ninot, G; Nyembue, T D; O'Hehir, R E; Ohta, K; Okamoto, Y; Okubo, K; Ouedraogo, S; Paggiaro, P; Pali-Schöll, I; Panzner, P; Papadopoulos, N; Papi, A; Park, H S; Passalacqua, G; Pavord, I; Pawankar, R; Pengelly, R; Pfaar, O; Picard, R; Pigearias, B; Pin, I; Plavec, D; Poethig, D; Pohl, W; Popov, T A; Portejoie, F; Potter, P; Postma, D; Price, D; Rabe, K F; Raciborski, F; Radier Pontal, F; Repka-Ramirez, S; Reitamo, S; Rennard, S; Rodenas, F; Roberts, J; Roca, J; Rodriguez Mañas, L; Rolland, C; Roman Rodriguez, M; Romano, A; Rosado-Pinto, J; Rosario, N; Rosenwasser, L; Rottem, M; Ryan, D; Sanchez-Borges, M; Scadding, G K; Schunemann, H J; Serrano, E; Schmid-Grendelmeier, P; Schulz, H; Sheikh, A; Shields, M; Siafakas, N; Sibille, Y; Similowski, T; Simons, F E R; Sisul, J C; Skrindo, I; Smit, H A; Solé, D; Sooronbaev, T; Spranger, O; Stelmach, R; Sterk, P J; Sunyer, J; Thijs, C; To, T; Todo-Bom, A; Triggiani, M; Valenta, R; Valero, A L; Valia, E; Valovirta, E; Van Ganse, E; van Hage, M; Vandenplas, O; Vasankari, T; Vellas, B; Vestbo, J; Vezzani, G; Vichyanond, P; Viegi, G; Vogelmeier, C; Vontetsianos, T; Wagenmann, M; Wallaert, B; Walker, S; Wang, D Y; Wahn, U; Wickman, M; Williams, D M; Williams, S; Wright, J; Yawn, B P; Yiallouros, P K; Yusuf, O M; Zaidi, A; Zar, H J; Zernotti, M E; Zhang, L; Zhong, N; Zidarn, M; Mercier, J

    2016-01-01

    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network. It is deployed in collaboration with the World Health Organization Global Alliance against Chronic Respiratory Diseases (GARD). The European Innovation Partnership on Active and Healthy Ageing has proposed a 5-step framework for developing an individual scaling up strategy: (1) what to scale up: (1-a) databases of good practices, (1-b) assessment of viability of the scaling up of good practices, (1-c) classification of good practices for local replication and (2) how to scale up: (2-a) facilitating partnerships for scaling up, (2-b) implementation of key success factors and lessons learnt, including emerging technologies for individualised and predictive medicine. This strategy has already been applied to the chronic respiratory disease action plan of the European Innovation Partnership on Active and Healthy Ageing. PMID:27478588

  13. Adapted Physical Activity Programme and Self-Perception in Obese Adolescents with Intellectual Disability: Between Morphological Awareness and Positive Illusory Bias

    Salaun, Laureline; Reynes, Eric; Berthouze-Aranda, Sophie E.

    2014-01-01

    Background: In adolescents with intellectual disability, the management of obesity is a crucial issue, yet also quite complex because of their particular perception of themselves. This study investigated the relationship between self-perception variables and morphological variables and their changes after a 9-month Adapted Physical Activity (APA)…

  14. Validation of k(0) standardization method in neutron activation analysis-The use of Kayzero for Windows programme at the nuclear physics institute, Rez

    Kubešová, Marie; Kučera, Jan

    2010-01-01

    Roč. 622, č. 2 (2010), s. 403-406. ISSN 0168-9002 Institutional research plan: CEZ:AV0Z10480505 Keywords : neutron activation analysis * k(0) standardization * Validation Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 1.142, year: 2010

  15. The Agency's technical co-operation programme with Myanmar 1985-1995 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Myanmar carried out during 1985-1995. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  16. The Agency's technical co-operation programme with The Philippines 1984-1994 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in The Philippines carried out during 1984-1994. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  17. The Agency's technical co-operation programme with Turkey 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Turkey carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  18. The Agency's technical co-operation programme with Nicaragua 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Nicaragua carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  19. The Agency's technical co-operation programme with Hungary 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Hungary carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  20. The Agency's technical co-operation programme with Malaysia 1984-1994 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Malaysia carried out during 1984-1994. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  1. The Agency's technical co-operation programme with Thailand 1984-1994 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Thailand carried out during 1984-1994. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  2. The Agency's technical co-operation programme with Paraguay 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Paraguay carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  3. The Agency's technical co-operation programme with Bangladesh 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Bangladesh carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  4. The Agency's technical co-operation programme with Bangladesh 1984-1994 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Bangladesh carried out during 1984-1994. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  5. The Agency's technical co-operation programme with Colombia 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Colombia carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  6. The Agency's technical co-operation programme with Bolivia 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Bolivia carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  7. The Agency's technical co-operation programme with Paraguay 1984-1994 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Paraguay carried out during 1984-1994. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  8. The Agency's technical co-operation programme with Greece 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Greece carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  9. The Agency's technical co-operation programme with Jamaica 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Jamaica carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  10. The Agency's technical co-operation programme with Mexico 1986-1996 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Mexico carried out during 1986-1996. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  11. The Agency's technical co-operation programme with Egypt 1985-1995 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Egypt carried out during 1985-1995. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  12. The Agency's technical co-operation programme with Turkey 1986-1996 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Turkey carried out during 1986-1996. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  13. The Agency's technical co-operation programme with Pakistan 1985-1995 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Pakistan carried out during 1985-1995. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  14. The Agency's technical co-operation programme with Indonesia 1984-1994 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Indonesia carried out during 1984-1994. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  15. The Agency's technical co-operation programme with Bolivia 1986-1996 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Bolivia carried out during 1986-1996. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  16. The Agency's technical co-operation programme with Guatemala 1985-1995 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Guatemala carried out during 1985-1995. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  17. The Agency's technical co-operation programme with Mongolia 1985-1995 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Mongolia carried out during 1985-1995. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  18. The Agency's technical co-operation programme with Cyprus 1984-1994 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Cyprus carried out during 1984-1994. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  19. The Agency's technical co-operation programme with Panama 1985-1995 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Panama carried out during 1985-1995. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  20. The Agency's technical co-operation programme with Portugal 1984-1994 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Portugal carried out during 1984-1994. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  1. The Agency's technical co-operation programme with Albania 1984-1994 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Albania carried out during 1984-1994. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  2. The Agency's technical co-operation programme with the Philippines 1985-1995 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Philippines carried out during 1985-1995. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  3. The Agency's technical co-operation programme with Viet Nam 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Viet Nam carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  4. The Agency's technical co-operation programme with Ecuador 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Ecuador carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  5. The Agency's technical co-operation programme with Sri Lanka 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Sri Lanka carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  6. The Agency's technical co-operation programme with El Salvador 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in El Salvador carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  7. The Agency's technical co-operation programme with Poland 1983-1993 country programme summaries

    This report contains a review of the Agency's technical co-operation activities in Poland carried out during 1983-1993. In terms of coverage and analytical depth, country programmes summaries stand somewhere midway between in-depth country programme evaluations and individual project evaluations. They attempt to provide a comprehensive, descriptive picture of the Agency's co-operation with a Member State in a manner that will be particularly useful for programming decisions. The attempt is very much to describe - largely through statistical data - not to provide independent analysis and evaluation

  8. An automatic bibliography indexing programme

    J. W. Morris

    1974-12-01

    Full Text Available A relatively simple FORTRAN IV programme, designed for a small computer, for author and key-word indexes to bibliographic records is described, and examples of output are given. It is com­pared with some other systems. Suggested improvements to the programme are given.

  9. The Wind Energy programme - SFOE Research Programme 2000 - 2003; Programm Wind. Konzept BFE-Forschungsprogramm 'Wind' 2000 - 2003

    Horbaty, R.

    2001-07-01

    This document, issued by the Swiss Federal Office of Energy (SFOE) describes the concept behind the Swiss wind energy programme. The first part of the report discusses the origins and development of the wind energy programme in Switzerland, discussing the importance of wind energy and policy matters associated with its promotion. The experience gained during the previous research programmes is reviewed. The degree to which targets were reached, promotional activities, the central government's own wind energy activities and the results of a programme evaluation are discussed. Lists of projects that have been realised and activities that have been carried out are presented and positive and negative influences on development are noted. A second part is dedicated to the goals of the wind energy programme in terms of target figures for the year 2010 and the strategies chosen to reach these goals, including pilot and demonstration projects (P and D) and promotional activities. Details of the P and D programme including lists of wind-power projects to be supported, the priorities that have been set and information and further education that is to be provided, are given. New activities in the wind power area such as the development of new type of wind turbine especially suited to alpine conditions are discussed. The role of the Swiss Association for Wind Energy 'Suisse Eole' as a network-partner in the wind energy programme is discussed. An appendix provides details of wind energy projects in Switzerland, market partners and customers. The results of a survey made of wind energy activities at Swiss institutes of higher education are presented.

  10. The Durham Micro-Optics Programme

    Schmoll, J.; Dubbeldam, C. M.; Robertson, D. J.; Yao, J

    2005-01-01

    The Durham Micro-optics Programme was established to develop key components to be used for integral field spectrographs for upcoming instrumentation projects, focussing on currently existing telescopes as well as on the next generation of ELTs. These activities include monolithic multi-optics machining and grinding, optical surface improvement using various post-polishing techniques and replication of micro-optical components. While these developments have mostly slicer-type IFUs in mind, als...

  11. Macroeconomic aspects of the French nuclear programme

    The nuclear programme is a boost both to economic and industrial activity and to research and development: it provides 120 000 jobs in France and has a positive influence on the national economic situation. After illustrating this statement, the author draws up a balance sheet for the nuclear industry, demonstrating the positive contribution of this form of energy compared with the results which would have been obtained by a different policy founded on electricity derived from coal

  12. Validation of k0 standardization method in neutron activation analysis-The use of Kayzero for Windows programme at the nuclear physics institute, Rez

    The goal of this work was to validate the method of the k0 standardization in neutron activation analysis at the laboratory of neutron activation analysis in Rez using the Kayzero for Windows software package. For verification of the precision and accuracy of the method two types of reference materials were used. One was a set of synthetic materials aimed at checking the implementation of k0 standardization. The others were matrix standard reference materials of the US National Institute of Standards and Technology comprising several types of matrices. In general, good agreement was obtained between results of this work and values in certificates of the individual reference materials, thus proving the accuracy of our results and successful implementation of the method for analysis of real samples. In addition, detection limits for more than 50 elements were evaluated.

  13. Integrating the promotion of physical activity within a smoking cessation programme: Findings from collaborative action research in UK Stop Smoking Services

    Taylor, A. H.; Everson-Hock, E S; Ussher, M.

    2010-01-01

    Background: Within the framework of collaborative action research, the aim was to explore the feasibility of developing and embedding physical activity promotion as a smoking cessation aid within UK 6/7-week National Health Service (NHS) Stop Smoking Services. Methods: In Phase 1 three initial cycles of collaborative action research (observation, reflection, planning, implementation and re-evaluation), in an urban Stop Smoking Service, led to the development of an integrated in...

  14. Integrating the promotion of physical activity within a smoking cessation programme: Findings from collaborative action research in UK Stop Smoking Services

    Taylor, Adrian H; Everson-Hock, Emma S; Ussher, Michael

    2010-01-01

    Background Within the framework of collaborative action research, the aim was to explore the feasibility of developing and embedding physical activity promotion as a smoking cessation aid within UK 6/7-week National Health Service (NHS) Stop Smoking Services. Methods In Phase 1 three initial cycles of collaborative action research (observation, reflection, planning, implementation and re-evaluation), in an urban Stop Smoking Service, led to the development of an integrated intervention in whi...

  15. Estimating the experimental value of the electromagnetic fine structure constant α-bar 0=1/137.036 using the Leech lattice in conjunction with the monster group and Spher's kissing number in 24 dimensions

    We start with various observations regarding the kissing number in the 24-dimensional Leech lattice Nτ(24)=196560 as well as the j-function coefficient b=196884 and the minimal dimension in which the monster group can act Dm=196883. Subsequently based on the previous results and earlier numerical experiments, we use a quibic potential to derive a quadratic equationx2+12820x-(Nτ(24)/10)=0where 128=spin 7=(2)7, 10=D(10) and Nτ(24)=196560 are the spin representation, the super string dimension and the Leech kissing number, respectively. It is found that the only positive solution of this equation isx1=137.036=α-bar 0which is the accurate experimental value of inverse of the electromagnetic fine structure constant. This remarkable result is interpreted in terms of the connection between the Moonshine conjecture and string theory as well as the E-infinity relation between the kissing number in 10 dimensions Kτ(10)=336 and the degrees of freedom of Klein's modular space dim Γ(7)=336

  16. Estimating the experimental value of the electromagnetic fine structure constant {alpha}-bar {sub 0}=1/137.036 using the Leech lattice in conjunction with the monster group and Spher's kissing number in 24 dimensions

    El Naschie, M.S. [King Abdul Aziz City of Science and Technology, Riyadh (Saudi Arabia)

    2007-04-15

    We start with various observations regarding the kissing number in the 24-dimensional Leech lattice N{sub {tau}}{sup (24)}=196560 as well as the j-function coefficient b=196884 and the minimal dimension in which the monster group can act D{sub m}=196883. Subsequently based on the previous results and earlier numerical experiments, we use a quibic potential to derive a quadratic equationx{sup 2}+12820x-(N{sub {tau}}{sup (24)}/10)=0where 128=spin 7=(2){sup 7}, 10=D{sup (10)} and N{sub {tau}}{sup (24)}=196560 are the spin representation, the super string dimension and the Leech kissing number, respectively. It is found that the only positive solution of this equation isx{sub 1}=137.036={alpha}-bar {sub 0}which is the accurate experimental value of inverse of the electromagnetic fine structure constant. This remarkable result is interpreted in terms of the connection between the Moonshine conjecture and string theory as well as the E-infinity relation between the kissing number in 10 dimensions K{sub {tau}}{sup (10)}=336 and the degrees of freedom of Klein's modular space dim {gamma}(7)=336.

  17. Radon programme in the Czech Republic

    The framework of the Radon programme in the Czech republic includes both precautionary measures and interventions. The programme informally started in early eighties has been now incorporated in national legislation (Atomic Act, Radiation Protection Decree, etc.). Aim of precautionary measures is to avert construction of building above natural radiation guidance levels (200 Bq/m3 for indoor radon concentration and 0.5 Sv/h for gamma dose rate) by protection of new buildings against soil radon ingress, by regulation of natural radioactivity in building materials and supplied water. Aim of interventions is to identify buildings affected by enhanced natural radioactivity and help owners to put into effect reasonable remedial measures. Two sets of intervention levels for indoor natural exposure were established: guidance intervention levels 400 Bq/m3 (indoor radon), 1.0 Sv/h (indoor gamma dose rate) and limit values 4000 Bq/m3 and 10 Sv/h. The radon programme is based both on governmental and private activities. The governmental activities include representative and targeted indoor radon survey, subsidy for radon mitigation, mitigation test measurements and public information on radon issue. The private activities include radon measurement (radon index of building site, indoor measurements, radon diagnosis) and remedial measures. More than 100 commercial companies were authorised by Radiation Protection Authority (SUJB) to provide these measurements

  18. The IAEA isotope and radiation programme

    The IAEA isotope and radiation programme is characterized by the very large number of topics dealt with and the broad range of activities where nuclear methods and techniques are utilized. The main activities of the programme can be grouped into: food and agriculture, human health and life science, industry and physical science, and laboratory services. Radioisotope and radiation based techniques are applied to such areas as plant breeding, insect and pest control, soil fertility studies, animal health and production, studies on the fate of pesticide residues and radionuclides in the food chain, and food preservation. General objectives of the second group of activities are to assist hospitals and research institutes in developing member states in the introduction and development of radionuclide tracers in medical diagnosis and research, to promote use of radiation therapy for cancer treatment, etc. The major objective of the third group is to foster research and application of nuclear methodologies for industrial applications in developing countries. The Agency's Laboratories at Seibersdorf and in Vienna and the Monaco Laboratory play a relevant role in providing laboratory services as a back-up for various programmes, and in the training of scientists from developing countries. (Nogami, K.)

  19. EURATOM Research Framework Programme on Reactor Systems

    The activities of the European Commission (EC) in the field of nuclear energy are governed by the Treaty establishing the European Atomic Energy Community (EURATOM). The research activities of the European Union (EU) are designed as multi-annual Framework Programmes (FP). The EURATOM 6. Framework Programme (EURATOM FP -6), covering the period 2002-2006, is funded with a budget of 1, 230 million Euros and managed by the European Commission. Beyond the general strategic goal of the EURATOM Framework Programmes to help exploit the potential of nuclear energy, in a safe and sustainable manner, FP -6 is designed to contribute also to the development of the 'European Research Area' (ERA), a concept described in the Commission's Communication COM(2000)6, of January 2000. Moreover EURATOM FP-6 contributes to the creation of the conditions for sharing the same nuclear safety culture throughout the EU-25 and the Candidate Countries, fostering the acceptance of nuclear power as an element of the energy mix. This paper gives an overview of the research activities undertaken through EURATOM FP-6 in the area of Reactor Systems, covering the safety of present reactors, the development of future safe reactors, and the needs in terms of research infrastructures and education and training. The actions under FP-6 are presented in their continuity of actions under FP-5. The perspectives under FP -7 are also provided. Other parts of the EURATOM FP, covering Waste Handling and Radiation Protection, as well as Fusion Energy, are not detailed in this paper. (authors)

  20. France's nuclear power programme

    The prospects of development of France's consumption of electricity will widen the deficit of her national energy resources. Nuclear power stations should enable this deficit to be reduced, provided a certain number of uncertainties prevailing today are resolved. The first programme, put forward by Messrs. AILLERET and TARANGER at the 1955 Geneva Conference aimed at commissioning 850 MWe by 1965; the programme was devoted to developing the natural uranium graphite-gas sequence and reaches its completion with the construction of EDF 3, the world's first unit capable of 500 MWe. Before changing over from the prototype stage to their duplication, Electricite De France decided, in agreement with the Commissariat A L'energie Atomique to build EDF 4, which, while reproducing EDF 3's reactor, together with the referring equipment, the entire control equipment and various other systems, pioneers an important innovation by incorporating the heat exchangers and fans inside the prestressed concrete pressure vessel housing the core. At the same time, studies are being carried on on the same type of reactor enabling possible use of a new annular-shaped fuel element, whose use would considerably improve the performance of EDF 5, to be envisaged. On the heavy water side, the construction of EL 4 at Brennilis jointly by the Commissariat A L'energie Atomique and Electricite De France is continuing. Design work on a 500 MWe reactor of this type has already started. As regards pressurized water reactors, the Chooz power station is built jointly by Electricite De France and Belgian Utilities. Finally, the Commissariat A L'energie Atomique is continuing the construction of the 'Rapsodie' rapid neutron reactor at Cadarache, together with studies on a larger power reactor. It may thus be seen that the technical and economic knowledge gained on these various types of reactor mean that an equipment program may be contemplated which will endow nuclear power stations with a place of ever

  1. Multinational Design Evaluation Programme. Annual Report - April 2014-April 2015

    The Multinational Design Evaluation Programme (MDEP) is a multinational initiative to leverage the resources and knowledge of national regulatory authorities who are, or will shortly be, undertaking the review of new reactor power plant designs. MDEP incorporates a broad range of activities including enhancing multilateral co-operation within existing regulatory frameworks, and increasing multinational convergence of codes, standards, guides and safety goals. A key concept throughout the work of MDEP is that national regulators retain sovereign authority for all licensing and regulatory decisions. Working groups are implementing the activities in accordance with programme plans with specific activities and goals, and have established the necessary interfaces both within and outside of MDEP. This report provides a status of the programme after its seventh year of implementation. Content: Executive summary; 1. Introduction; 2. Programme goals and outcomes; 3. Programme implementation (Membership, Organisational structure, MDEP Library, Common positions); 4. Interactions with other organisations; 5. Current activities (EPR Working Group (EPRWG), AP1000 Working Group (AP1000WG), APR1400 Working Group (APR1400WG), VVER Working Group (VVERWG), AVBWR Working Group (ABWRWG), Vendor Inspection Co-operation Working Group (VICWG), Codes and Standards Working Group (CSWG), Digital Instrumentation and Controls Working Group (DICWG)); 6. Interim results; 7. Next steps - Future of the programme; Appendix 1 - List of abbreviations and acronyms; Appendix 2 - Revised documents and publications; Appendix 3 - Photographs of reactors considered within MDEP

  2. Management and Communication programme

    Nathalie Dumeaux

    2005-01-01

    We are pleased to announce the launch of three new courses in the Management and Communication programme: 1.     Managing Time (Open to all Staff Members) The objectives are: To enhance your personal effectiveness through better organisation skills To acquire ways of making the most of your time through improved work habits To reduce stress For the description of this course, please see:  http://humanresources.web.cern.ch/humanresources/external/training/MANCO/P9798/S8E_e.asp 2.     Service Orientation (Open to all Staff Members working in a service-related function) The objectives are: To understand the key elements in an effective client/service provider relationship To develop a client focused approach to providing services For the description of this course, please see:  http://humanresources.web.cern.ch/humanresources/external/training/MANCO/P9798/serv_e.asp 3.   Introduction to Leadership (Open to Staff in Career Paths E & above, including newly appointed supervisors and Secti...

  3. Management and Communication programme

    Nathalie Dumeaux

    2005-01-01

    We are pleased to announce the launch of three new courses in the Management and Communication programme: 1.     Managing Time (Open to all Staff Members) The objectives are: To enhance your personal effectiveness through better organisation skills To acquire ways of making the most of your time through improved work habits To reduce stress For the description of this course, please see:  http://humanresources.web.cern.ch/humanresources/external/training/MANCO/P9798/S8E_e.asp 2.     Service Orientation (Open to all Staff Members working in a service-related function) The objectives are: To understand the key elements in an effective client/service provider relationship To develop a client focused approach to providing services For the description of this course, please see:  http://humanresources.web.cern.ch/humanresources/external/training/MANCO/P9798/serv_e.asp 3.   Introduction to Leadership (Open to Staff in Career Paths E & above, including newly appointed supervisors and Sect...

  4. SUMMER STUDENT LECTURE PROGRAMME

    Françoise Benz

    2002-01-01

    SUMMER STUDENT LECTURE PROGRAMME Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Monday 29 July 09:15 - 10:00 R. RATTAZZI Beyond the Standard Model (3/3) 10:15 - 11:00 P. WELLS Experimental test of the SM - LEP (3/3) 11:15 - 12:00 P. WELLS Discussion Session 14:00 - 16:00 R. ASSMANN The CLIC Concept for a Future Particle Collider at the Energy Frontier Tuesday 30 July 09:15 - 10:00 F. ANTINORI Heavy Ions (1/2) 10:15 - 12:00 F. DYDAK Neutrino Physics (1&2/4) Wednesday 31 July  09:15 - 10:00 F. ANTINORI Heavy Ions (2/2) 10:15 - 11:00 F. DYDAK Neutrino Physics (3/4) 11:15 - 12:00 F. DYDAK / F. ANTINORI Discussion Session Thursday 1 August 09:15 - 10:00 T. NAKADA CP Violation (1/4) 10:15 - 11:00 F. DYDAK Neutrino Physics (4/4) 11:15 - 12:00 F. BEDESCHI Experimental test of the SM Tevatron (1/2) Friday 2 August 09:15 - 10:00 T. NAKADA CP Violation (2/4) 10:15 ? 11:00 F. BEDESCHI Experimental test of the SM Tevatron (2/2) 11:15 ? 12:00 F. BEDESCHI / T. NAKADA Di...

  5. SUMMER STUDENT LECTURE PROGRAMME

    Françoise Benz

    2002-01-01

    Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Wednesday 3 July 09:15 - 10:00 L. FAYARD, O. ULLALAND Presentation of the Summer Student Programm 10:15 - 12:00 L. MAIANI Introduction to CERN (1&2/2) 14:00 - 15:00 G. Stevenson Radiation Protection (Council Chamber, bldg.503) Thursday 4 July 09:15 - 11:00 F. CLOSE Introduction to Particle Physics for non Physics Students (1&2/4) 11:15 - 12:00 C. JORAM Particle Detectors (1/5) Friday 5 July 09:15 - 11:00 F. CLOSE Introduction to Particle Physics for non Physics Students (3&4/4) 11:15 - 12:00 Discussion Session Monday 8 July 09:15 - 10:00 R. KLEISS Fundamental Concepts of Particle Physics (1/6) 10:15 - 11:00 C. JORAM Particle Detectors (2/5) 11:15 - 12:00 M. FRANKLIN Classic Experiments (1/3) 14:00 - 15:00 M. LINDROOS Isolde 15:30 - 16:30 M. LINDROOS Visit of the Experiment Tuesday 9 july 09:15 - 10:00 R. KLEISS Fundamental Concepts of Particle Physics (2/6) 10:15 - 11:00 C. JORAM Part...

  6. Scientific Programme Committee

    2013-02-01

    Scientific Programme Committee A. Blondel, University of Geneva A. Cervera, IFIC M. Dracos, IN2P3 I. Efhymiopoulos, CERN J. Ellis, CERN S. Geer, FNAL R. Garoby, CERN M. Goodman, ANL D. Harris, FNAL T. Hasegawa, KEK P. Huber, Virginia Tech. D. Kaplan, IIT Y.D. Kim, Sejong University H. Kirk, BNL Y. Kuno, Osaka University K. Long, Imperial College N.K. Mondal, TIFR J. Morfin, FNAL Y. Mori, Kyoto University K. Nishikawa, KEK V. Palladino, University of Napoli C. Prior, RAL F.J.P. Soler, University of Glasgow J. Strait, FNAL R. Svoboda, University of California Davis F. Terranova, LN Frascati M. Zisman, LBNL Local Organizing Committee E. Benedetto, CERN/NTUA C. Blanchard, University of Geneva A. Blondel, University of Geneva (co-chair) I. Efthymiopoulos, CERN (co-chair) F. Dufour, University of Geneva F. Girard-Madoux, CERN E. Gschwendtner, CERN A. Korzenev, University of Geneva M. Morer-Olafsen, CERN S. Murphy, University of Geneva G. Prior, CERN G. Wikström, University of Geneva E. Wildner, CERN Sponsors EuCARD European Organization for Nuclear Research (CERN) Swiss Institute for Particle Physics (CHIPP) University of Geneva

  7. Summer Student Programme

    2006-01-01

    Date Time Title Speaker 05/07/2006 09:15 - 10:00 Presentation of the Summer Student Programme F. CERUTTI Information on Computing Rules D. HEAGERTY Workshops presentation O. ULLALAND 10:15 - 11:00 Introduction to CERN J. ENGELEN 11:15 Film on CERN 11:00 Introduction to Particle Physics F. CLOSE 11:15 - 12:00 Accelerators (1/5) S. GILARDONI / E. METRAL 12:00 Discussion Session 7/07/2006 09:15 - 11:00 Introduction to Particle Physics F. CLOSE 11:15 - 12:00 Accelerators (2/5) S. GILARDONI / E. METRAL 12:00 Discussion Session 09:15 - 10:00 Accelerators (3/5) S. GILARDONI / E. METRAL 10:15 - 12:00 Detectors (1-2/5) O. ULLALAND 12:00 Discussion Session 11/07/2006 09:15 - 10:00 Accelerators (4/5) S. GILARDONI / E. METRAL 10:15 - 11:00 Detectors (3/5) O. ULLALAND 11:15 - 12:00 Introduction to Nuclear Physics (1/4) P. CHOMAZ P. CHOMAZ 10:15 - 11:00 Accelerators (5/5) S. GILARDONI / E. METRAL 11:15 - 12:00 Detectors (4/5) O. ULLALAND 12:00 Discus...

  8. Summer Student Lecture Programme

    2004-01-01

    Main Auditorium, bldg. 500 More Information DATE TIME LECTURER TITLE Wednesday 7 July 09:15 - 10:00 L. Fayard, O. Ullaland, D. Heagerty (CERN) Programme Presentation Workshops presentation Information on Computing Rules 10:15 - 11:00 R. Aymar (CERN) Introduction to CERN (1/2) 11:15 - 12:00 J. Engelen (CERN) Introduction to CERN (2/2) 15:00 - 16:30 H. Menzel (CERN) An Introduction to Radiation Protection DATE TIME LECTURER TITLE Thursday 8 july 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physics (1/4) 10:15 - 11:00 L. Di Lella (CERN) Introduction to Particle Physics (2/4) 11:15 - 12:00 P. Chomaz (GANIL / CERN) Fundamental questions in modern nuclear physics: The challenge of exotic nuclei (1/2) DATE TIME LECTURER TITLE Friday 9 July 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physics (3/4) 10:15 - 11:00 P. Chomaz (GANIL / CERN) Fundamental questions in modern nuclear physics: The challenge of exotic nuclei (2/2) 11:15 - 12:00 P....

  9. Programmable electronic synthesized capacitance

    Kleinberg, Leonard L. (Inventor)

    1987-01-01

    A predetermined and variable synthesized capacitance which may be incorporated into the resonant portion of an electronic oscillator for the purpose of tuning the oscillator comprises a programmable operational amplifier circuit. The operational amplifier circuit has its output connected to its inverting input, in a follower configuration, by a network which is low impedance at the operational frequency of the circuit. The output of the operational amplifier is also connected to the noninverting input by a capacitor. The noninverting input appears as a synthesized capacitance which may be varied with a variation in gain-bandwidth product of the operational amplifier circuit. The gain-bandwidth product may, in turn, be varied with a variation in input set current with a digital to analog converter whose output is varied with a command word. The output impedance of the circuit may also be varied by the output set current. This circuit may provide very small ranges in oscillator frequency with relatively large control voltages unaffected by noise.

  10. ALICE pp physics programme

    Kraus, Ingrid

    2009-01-01

    The physics programme of the ALICE experiment at CERN-LHC comprises besides studies of high-energy heavy-ion collisions measurements of proton-proton interactions at unprecedented energies, too. This paper focuses on the global event characterisation in terms of the multiplicity distribution of charged hadrons and mean transverse momentum. These bulk observables become accessible because the detector features excellent track reconstruction, especially at low transverse momenta. The measurement of strange hadrons is of particular interest since the strange-particle phase-space was found to be suppressed beyond canonical reduction at lower center-of-mass energies and the production mechanism of soft particles is not yet fully understood. Here we benefit in particular from particle identification down to very low transverse momentum, i.e. 100 - 300 MeV/c, giving access to spectra and integrated yields of identified hadrons. Equipped with these features, ALICE will play a complementary role w.r.t. other LHC exper...

  11. The BGAN extension programme

    Rivera, Juan J.; Trachtman, Eyal; Richharia, Madhavendra

    2005-11-01

    Mobile satellite telecommunications systems have undergone an enormous evolution in the last decades, with the interest in having advanced telecommunications services available on demand, anywhere and at any time, leading to incredible advances. The demand for braodband data is therefore rapidly gathering pace, but current solutions are finding it increasingly difficult to combine large bandwidth with ubiquitous coverage, reliability and portability. The BGAN (Broadband Global Area Network) system, designed to operate with the Inmarsat-4 satellites, provides breakthrough services that meet all of these requirements. It will enable broadband connection on the move, delivering all the key tools of the modern office. Recognising the great impact that Inmarsat's BGAN system will have on the European satellite communications industry, and the benefits that it will bring to a wide range of European industries, in 2003 ESA initiated the "BGAN Extension" project. Its primary goals are to provide the full range of BGAN services to truly mobile platforms, operating in aeronautical, vehicular and maritime environments, and to introduce a multicast service capability. The project is supported by the ARTES Programme which establishes a collaboration agreement between ESA, Inmarsat and a group of key industrial and academic institutions which includes EMS, Logica, Nera and the University of Surrey (UK).

  12. Digitally programmable signal generator

    A digitally programmable signal generator (DPSG) includes a first memory from which data is written into a second memory formed of n banks. Each bank includes four memories and a multiplexer, the banks being read once during each time frame, the read-out bits being multiplexed and fed out serially in synchronism with a plurality of clock pulses occuring during a time frame. The resulting serial bit streams may be fed in parallel to a digital-to-analog converter. The DPSG can be used in applications such as Atomic Vapor Laser Isotope Separation (AVLIS) to create an optimal match between the process laser's spectral profile and that of the vaporized material, optical telecommunications, non-optical telecommunication in the microwave and radio spectrum, radar, electronic countermeasures, high speed computer interconnects, local area networks, high definition video transport and the multiplexing of large quantities of slow digital memory into high speed data streams. This invention extends the operation of DPSGs into the GHz range. (author)

  13. Fusion technology programme

    In 1982, KfK joined the fusion programme of EURATOM as a further association introducing its experience in nuclear technology. KfK closely cooperates with IPP Garching, the two institutions forming a research unit aiming at planning and realization of future development steps of fusion. KfK has combined its forces in the Nuclear Fusion Project (PKF) with participation of several KfK departments to the project tasks. Previous work of KfK in magnetic fusion has addressed mainly superconducting magnets, plasma heating by cluster ions and studies on structural materials. At present, emphasis of our work has concentrated increasingly on the nuclear part, i.e. the first wall and blanket structures and the elements of the tritium extraction and purification system. Associated to this component development are studies of remote maintenance and safety. Most of the actual work addresses NET, the next step to a demonstration of fusion feasibility. NET is supposed to follow JET, the operating plasma physics experiment of Euratom, on the 1990's. Detailed progress of the work in the past half year is described in this report. (orig./GG)

  14. Swedish waste management programme

    Sweden has developed a comprehensive system for the management of all wastes arising from its nuclear power production. An interim storage for spent nuclear fuel is in operation since 1985. A repository for low and medium level waste has been constructed and is in operation since 1988. Transportation of the fuel and other radioactive wastes is made by a sea transport system. The existing facilities will with some moderate expansion be sufficient to handle all radioactive wastes for a long time. An encapsulation plant for spent nuclear fuel and a repository for final disposal of a limited amount of spent fuel is planned to be built till 2008. In the repository the fuel will be isolated by multiple engineered and geological barriers. The ongoing waste management RD and D-programme is mainly concerned with questions related to the encapsulation of fuel and construction of such a repository in the granitic bedrock in Sweden. During the 1990s the emphasize will be on finalizing the development and the design of the needed facilities and on the characterization of candidate repository sites. The cost for spent fuel management including final disposal has been calculated to 4800 SEK/kg U. (author). 6 figs

  15. FPGAs for software programmers

    Hannig, Frank; Ziener, Daniel

    2016-01-01

    This book makes powerful Field Programmable Gate Array (FPGA) and reconfigurable technology accessible to software engineers by covering different state-of-the-art high-level synthesis approaches (e.g., OpenCL and several C-to-gates compilers). It introduces FPGA technology, its programming model, and how various applications can be implemented on FPGAs without going through low-level hardware design phases. Readers will get a realistic sense for problems that are suited for FPGAs and how to implement them from a software designer’s point of view. The authors demonstrate that FPGAs and their programming model reflect the needs of stream processing problems much better than traditional CPU or GPU architectures, making them well-suited for a wide variety of systems, from embedded systems performing sensor processing to large setups for Big Data number crunching. This book serves as an invaluable tool for software designers and FPGA design engineers who are interested in high design productivity through behavi...

  16. Environmental control programme for the pipeline construction activities - a practical viewing; Programa de controle ambiental das atividades de construcao de dutos. Uma visao pratica

    Henrique, Paulo R.P.; Freitas, Eduardo L. [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    1998-07-01

    The environmental Control Plan of the Construction Activities of the Pipeline is a planning tool which sets forth the guidelines and procedures to be adopted by the companies in charge of the construction, so as to manage and minimize the environmental impacts arising from its implementation throughout the several steps of the work. Most of the impacts on the soil, vegetation, wildlife and population are local, on a space and timely basis, and occur mainly during the pipeline implementation. Such impacts may, to a great extend, be mitigated to acceptable levels through the application of the measures provided here under during and after the construction. So, the main purposes of the present Plan are to avoid, minimized, control and litigate potential impacts arising from the construction and operation, and to assure continuous compliance with the applicable environmental legislation. (author)

  17. The determination of pesticide residues and contaminants in vegetables by means of neutron activation analysis. Part of a coordinated programme on nuclear detection and analysis

    Neutron activation techniques have been applied to study the existence of pesticide residues (As, Br, Hg) and pollutants (Cd, Co, Zn) in local vegetable and fruit samples, polished and unpolished glutinous and non-glutinous milled rice, and fish caught in polluted and unpolluted areas of the Gulf of Thailand. Since the baseline levels of these toxic elements in vegetables, fruits, rice and fish are not known as yet, the results cannot be regarded as conclusive. Furthermore, no significant difference was observed in the concentration of these elements in fish caught in polluted and unpolluted areas. The Gulf of Thailand does not therefore appear to be polluted at present. The substoichiometric isotope dilution technique was successfully applied to mercury determinations, and only to a limited extent to Cd due to shutdown of the TRR-1 reactor

  18. Hat das Internet ein Programm?

    Coy, Wolfgang

    1998-01-01

    Hat das Internet ein Programm? Ist der Papst katholisch? Natürlich hat das Internet Millionen Programme - solche, die es nutzt und solche die man per FTP - File Transfer Protocol auf die eigene Maschine herunter laden kann und solche, die sich unbemerkt auf der Festplatte festsetzen. Letztere heißen Viren, Würmer oder trojanische Pferde. Aber das sind natürlich Programme im Sinne der Informatik, nicht im Sinne der broadcast media. Im amerikanisch-englischen Sprachraum, dem die...

  19. International programme on the health effects of the Chernobyl accident

    A memorandum of understanding between the WHO and the Ministry of Health of the USSR was signed in April 1990, calling for the development of a long-term international programme to monitor and mitigate the health effects of the Chernobyl accident. This document reports on progress made to date in terms of technical management and coordination and financial aspects of the programme. It also provides information on future activities and discusses related issues

  20. The GAPS Programme with HARPS-N at TNG. VII. Putting exoplanets in the stellar context: magnetic activity and asteroseismology of $\\tau$ Bootis A

    Borsa, F; Rainer, M; Bignamini, A; Maggio, A; Poretti, E; Lanza, A F; Di Mauro, M P; Benatti, S; Biazzo, K; Bonomo, A S; Damasso, M; Esposito, M; Gratton, R; Affer, L; Barbieri, M; Boccato, C; Claudi, R U; Cosentino, R; Covino, E; Desidera, S; Fiorenzano, A F M; Gandolfi, D; Harutyunyan, A; Maldonado, J; Micela, G; Molaro, P; Molinari, E; Pagano, I; Pillitteri, I; Piotto, G; Shkolnik, E; Silvotti, R; Smareglia, R; Southworth, J; Sozzetti, A; Stelzer, B

    2015-01-01

    Aims. We observed the $\\tau$ Boo system with the HARPS-N spectrograph to test a new observational strategy aimed at jointly studying asteroseismology, the planetary orbit, and star-planet magnetic interaction. Methods. We collected high-cadence observations on 11 nearly consecutive nights and for each night averaged the raw FITS files using a dedicated software. In this way we obtained spectra with a high signal-to-noise ratio, used to study the variation of the CaII H&K lines and to have radial velocity values free from stellar oscillations, without losing the oscillations information. We developed a dedicated software to build a new custom mask that we used to refine the radial velocity determination with the HARPS-N pipeline and perform the spectroscopic analysis. Results. We updated the planetary ephemeris and showed the acceleration caused by the stellar binary companion. Our results on the stellar activity variation suggest the presence of a high-latitude plage during the time span of our observatio...

  1. Auto-programmable impulse neural circuits

    Watula, D.; Meador, J.

    1990-01-01

    Impulse neural networks use pulse trains to communicate neuron activation levels. Impulse neural circuits emulate natural neurons at a more detailed level than that typically employed by contemporary neural network implementation methods. An impulse neural circuit which realizes short term memory dynamics is presented. The operation of that circuit is then characterized in terms of pulse frequency modulated signals. Both fixed and programmable synapse circuits for realizing long term memory are also described. The implementation of a simple and useful unsupervised learning law is then presented. The implementation of a differential Hebbian learning rule for a specific mean-frequency signal interpretation is shown to have a straightforward implementation using digital combinational logic with a variation of a previously developed programmable synapse circuit. This circuit is expected to be exploited for simple and straightforward implementation of future auto-adaptive neural circuits.

  2. A long-term programme for IAEA

    At its fifth regular session in 1961, the IAEA General Conference adopted a resolution calling for the preparation of a long-term programme for the Agency's activities. The programme, which was prepared after extensive consultations with experts from many Member States and is intended to serve as a guide in planning and carrying out the Agency's work from 1965, has been presented to the seventh session of the General Conference by the Board of Governors and the Director General. It envisages that the Agency's main role during the next few years will be, on the one hand, to assist in preparing Member States for the introduction of atomic energy in its various peaceful uses, especially in the production of power, and, on the other, to stimulate and co-ordinate scientific and technological development with a view to making the advantages of peaceful atomic applications available to the maximum number of countries in the shortest possible time

  3. Neutron radiography in Indian space programme

    Viswanathan, K

    1999-01-01

    Pyrotechnic devices are indispensable in any space programme to perform such critical operations as ignition, stage separation, solar panel deployment, etc. The nature of design and configuration of different types of pyrotechnic devices, and the type of materials that are put in their construction make the inspection of them with thermal neutrons more favourable than any other non destructive testing methods. Although many types of neutron sources are available for use, generally the radiographic quality/exposure duration and cost of source run in opposite directions even after four decades of research and development. But in the area of space activity, by suitably combining the X-ray and neutron radiographic requirements, the inspection of the components can be made economically viable. This is demonstrated in the Indian space programme by establishing a 15 MeV linear accelerator based neutron generator facility to inspect medium to giant solid propellant boosters by X-ray inspection and all types of critic...

  4. Country programme frameworks. A special evaluation

    As a result of the recommendations of the TC Policy Review Seminar held in 1994 the Department of Technical Co-operation initiated Country Programme Framework (CPF) related activities in early 1995. Draft Guidelines for carrying out the CPF process were issued in February 1995. An agenda was propose for carrying gout the CPF process, which also included field missions to those countries where the information on national programmes and priorities available at the Agency was believed to be insufficient. In December 1995 the Evaluation Section was requested by the TC management to evaluate the approach and the progress achieved to date. The findings and conclusions of this evaluation have been formulated after extensive discussions with both in-house staff and external evaluation consultants. They thus represent a distillation of the views expressed by all. 2 figs, 1 tab

  5. Overview of OECD/NEA BEPU Programmes

    The OECD/NEA paved the way for the development and assessment of BEPU for about 40 years, through concrete tasks: International Standard Problems (ISPs), Benchmarking activities, Development of Validation Matrices, Joint Safety Research Projects, and Specialist meetings. Several NEA related Best-Estimate Plus Uncertainties (BEPU) programmes have been successfully completed: Uncertainty Methods Study (UMS), Best-Estimate Methods - Uncertainty and Sensitivity Evaluation (BEMUSE), Safety Margin Assessment and Application (SM2A), Uncertainty Analysis in Modeling (UAM) Benchmark. New Programmes are underway to address pending issues (e.g., input uncertainties, uncertainties in coupled codes). The present Workshop may highlight new issues to be addressed (e.g., uncertainty analysis for CFD codes). Document available in the slides-form only

  6. The Russian nuclear data research programme

    The report contains the Russian programme of nuclear data research, approved by the Russian Nuclear Data Committee on 16 December 1994. It gives surveys on nuclear data needs, on the structure of nuclear data activities, on experimental facilities for nuclear data measurements at five Russian institutes, on theoretical model work, nuclear data evaluation, and nuclear data testing. It describes four Russian nuclear data centers and their relations to the International Nuclear Data Centres Network, and their holdings of nuclear data libraries of Russian and international origin. A summary of nuclear data applications in energy and non-energy fields is given. An appendix contains a detail nuclear data research programme for the years 1995 - 2005. (author). 16 refs, 1 fig., 6 tabs

  7. Developing a public information programme in France

    In today's world, companies must initiate their own communications programmes or else they will be overtaken by others under circumstances and at times that are both generally unfavourable and not of their choosing. The development of a corporate communications programme is good for a company's commercial activities, for its management, and for its integration into its operating environment, as well as for its internal harmony. This is true for any company, regardless of its business sector. However, for companies in the nuclear field, such as the Cogema Group, do special considerations need to be taken into account? What is the communications track record of this industry? Should the overall communications strategy of a company be challenged based on this record? The questions are addressed in this paper. (author)

  8. The current wind energy programme in Italy

    In Italy, the main activities in the field of wind energy are carried out by two state-owned organizations, ENEA (Italian National Agency for New Technologies, Energy and the Environment) and ENEL (Italian National Electricity Board), and two major wind turbine generator manufacturers, Alenia/WEST and Riva Calzoni, within the framework of a national programme which is supervized by the Ministry of Industry and Commerce. The work currently under way concerns both wind power plant siting and the development and testing of Italian-made wind turbine generators ranging from 5 to 1500 kW in power. In addition, programmes aimed at constructing wind-farms made up of medium-sized machines (200-400 kW) have recently been launched

  9. The VULCANO spreading programme

    Among the currently studied core-catcher projects, some of them suppose corium spreading before cooling, in particular the EPR (European Pressurized Reactor) core-catcher concept is based on mixing the corium with a special concrete, spreading the molten mixture on a large multi-layer surface cooled from the bottom and subsequently cooling by flooding with water. Therefore, melt spreading deserves intensive investigation in order to determine and quantify key phenomena which govern the stopping of spreading. In France, for some years, the Nuclear Reactor Division of the Atomic Energy Commission (CEA/DRN) has undertaken a large program to improve knowledge on corium behaviour and coolability. This program is based on experimental and theoretical investigations which are finally gathered in scenario and mechanistic computer codes. In this framework, the real material experimental programme, VULCANO, conducted within an European frame, is currently devoted to the study of corium spreading. In 1997 and 1998, several tests have been performed on dry corium spreading with various composition of melts. Although all the observed phenomena, in particular the differences between simulant and real material melts have not been yet totally explained, these tests have already provided a lot of information about: The behaviour of complex mixtures including refractory oxides, silica, iron oxides and in one case iron metal; Spreading progression, which was never stopped in any of these tests by a crust formation at the front; The structure of spread melts (porosity, crusts,...); Physico-chemical interaction between melt and the refractory substratum which was composed of zirconia bricks. (authors)

  10. The Mice Drawer System (MDS) Tissue Sharing Programme: effect of space conditions on skin metabolic activity and vascularization and potential impact of radiations in mice.

    Nusgens, Betty; Lambert, Charles; Liu, Yi; Cancedda, Ranieri; Tavella, Sara; Ruggiu, Alessandra; Colige, Alain

    morphological and immunochemical analysis aim at investigating dermal and epidermal thickness, number and surface of blood vessels (CD31, VW factor, type IV collagen) and lymphatics (D2-40, Lyve), score of acanthosis and papillomatosis, proliferation index (Ki67), epidermal markers of differentiation and FXIIIa positive dendritic cells. Another fragment of skin is used for measuring water content, total collagen content (hydroxyproline) and total proteoglycans content (uronic acid). A differential extraction procedure allows to quantify the newly synthetized collagen and the progressively more heavily cross-linked colla-gen, the pattern of extraction reflecting the turn-over rate of collagen. Quantitative RT-PCR procedure is used to evaluate the expression of extracellular matrix components (fibrillar and FACIT collagens), the enzymes involved in their postranslational modifications (ADAMTS-2, -3, -14, BMP1, prolylhydroxylase, lysyloxydase), the MMPs and their physiologic activators and inhibitors, proteoglycans of the hyalectans family and the SLRP, hyaluronansynthase, ag-grecanases of the ADAMTS family, and vascular markers (CD31, VEGF-A, -C, -D, VEGF-R1, -R2, -R3, PlGF, NRP1 2, SEMA3). A special attention will be paid to the splice variants of VEGF-A. We recently discovered a new splice variant, VEGF111, lacking exons 5, 6 and 7, bio-logically active and resistant to proteolysis that is specifically induced by genotoxic agents such as radiations. Its expression might reflect an impact of radiations during the long stay of the animals in space environment. Additionally, a genome-wide analysis of gene expression will be performed using DNA microarrays (Affimetrix). Partial results of the analyses under way will be presented. http://www.nasa.gov/missionp ages/station/science/experiments/M DS.html

  11. Light-Activated Nuclear Translocation of Adeno-Associated Virus Nanoparticles Using Phytochrome B for Enhanced, Tunable, and Spatially Programmable Gene Delivery.

    Gomez, Eric J; Gerhardt, Karl; Judd, Justin; Tabor, Jeffrey J; Suh, Junghae

    2016-01-26

    Gene delivery vectors that are activated by external stimuli may allow improved control over the location and the degree of gene expression in target populations of cells. Light is an attractive stimulus because it does not cross-react with cellular signaling networks, has negligible toxicity, is noninvasive, and can be applied in space and time with unparalleled precision. We used the previously engineered red (R)/far-red (FR) light-switchable protein phytochrome B (PhyB) and its R light dependent interaction partner phytochrome interacting factor 6 (PIF6) from Arabidopsis thaliana to engineer an adeno-associated virus (AAV) platform whose gene delivery efficiency is controlled by light. Upon exposure to R light, AAV engineered to display PIF6 motifs on the capsid bind to PhyB tagged with a nuclear localization sequence (NLS), resulting in significantly increased translocation of viruses into the host cell nucleus and overall gene delivery efficiency. By modulating the ratio of R to FR light, the gene delivery efficiency can be tuned to as little as 35% or over 600% of the unengineered AAV. We also demonstrate spatial control of gene delivery using projected patterns of codelivered R and FR light. Overall, our successful use of light-switchable proteins in virus capsid engineering extends these important optogenetic tools into the adjacent realm of nucleic acid delivery and enables enhanced, tunable, and spatially controllable regulation of viral gene delivery. Our current light-triggered viral gene delivery prototype may be broadly useful for genetic manipulation of cells ex vivo or in vivo in transgenic model organisms, with the ultimate prospect of achieving dose- and site-specific gene expression profiles for either therapeutic (e.g., regenerative medicine) or fundamental discovery research efforts. PMID:26618393

  12. Electrically-programmable diffraction grating

    Ricco, A.J.; Butler, M.A.; Sinclair, M.B.; Senturia, S.D.

    1998-05-26

    An electrically-programmable diffraction grating is disclosed. The programmable grating includes a substrate having a plurality of electrodes formed thereon and a moveable grating element above each of the electrodes. The grating elements are electrostatically programmable to form a diffraction grating for diffracting an incident beam of light as it is reflected from the upper surfaces of the grating elements. The programmable diffraction grating, formed by a micromachining process, has applications for optical information processing (e.g. optical correlators and computers), for multiplexing and demultiplexing a plurality of light beams of different wavelengths (e.g. for optical fiber communications), and for forming spectrometers (e.g. correlation and scanning spectrometers). 14 figs.

  13. CERN openlab summer student programme

    2013-01-01

    CERN openlab is currently taking applications for its summer student programme. The closing date for applications is 31 March 2013.   The openlab summer student programme is open for applications from bachelor, master and PhD students in computer science and physics. Successful applicants will spend 9 weeks at CERN, during the period from June to September 2013, working with some of the latest hardware and software technologies. The programme is more than just a summer at CERN: it can lead to follow-on projects at the home institute and may even inspire students to become entrepreneurs in cutting-edge computing technologies. A series of lectures will be given by experts in various domains of CERN-related high-throughput computing. Study tours of external companies and universities as well as of CERN facilities are also part of the programme. Please visit the CERN openlab website for more information.

  14. CERN openlab Summer Student Programme

    2012-01-01

    CERN openlab is currently taking applications for its summer student programme. The closing date for applications is 30 March 2012.   The openlab Summer Student Programme is open for applications from bachelor, master and PhD students in computer science and physics. Successful applicants will spend 8 weeks at CERN, during the period June to September 2012, to work with some of the latest hardware and software technologies. The programme is more than just a summer at CERN: it can lead to follow-on projects at the home institute and may even inspire the students to become entrepreneurs in cutting-edge computing technologies. A series of lectures will be given by experts in various domains of CERN related high-throughput computing. Study tours to external companies and universities as well as to CERN facilities are also part of the programme. Please visit www.cern.ch/openlab-students for more information.

  15. Climate Ambassador Programmes in Municipalities

    Jørgensen, Michael Søgaard; Pedersen, Stine Rahbek

    Some Danish municipalities have developed ambassador programmes which generate environmental and climate change mitigation efforts in local public administrations and institutions. This chapter analyses the characteristics and experiences of four ambassador programmes now operating in the...... municipalities of Furesø, Lyngby-Taarbæk, Frederiksberg and Hvidovre. Two of the ambassador programmes presented here focus primarily on climate change mitigation initiatives, and two have a broader focus on sustainable development. Important elements for the impact of these programmes are the networking among...... the local ambassadors, the central coordinator’s ability to support the local ambassador with knowledge about mapping, reduction of environmental impacts and facilitation of development of initiatives, and mechanisms for the allocation of cost savings from local resource savings....

  16. Critical programme for nuclear safety

    This July should see the award of the first contracts under a Pound 25 million programme designed to lead to a better understanding of control systems for safety-critical uses. The research and development programme is aimed at safety-critical circuits in everything form electronically-controlled car suspensions to safety systems in nuclear power stations. This article looks specifically at the latter. (author)

  17. Field Evaluation of Programmable Thermostats

    Sachs, O. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Tiefenbeck, V. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Duvier, C. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Qin, A. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Cheney, K. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Akers, C. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Roth, K. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States)

    2012-12-01

    Prior research suggests that poor programmable thermostats usability may prevent their effective use to save energy. The Fraunhofer team hypothesized that home occupants with high-usability thermostats would be more likely to use them to save energy than people with a basic thermostats. In this report, the team discusses results of a project in which the team monitored and compared programmable thermostats with basic thermostats in an affordable housing apartment complex.

  18. The internationalisation of postgraduate programmes

    Fink, Flemming Kobberøe; Andersen, Ole K.; Bak, Thomas;

    2002-01-01

    This paper presents the efforts and experiences of globalisation of the study programmes within electronic engineering at Aalborg University. The Project-Organised Problem-Based Learning Model, which have been employed since 1974 is presented and discussed. The consequences this has for the inter...... international students are presented and discussed in terms of e.g. the teamwork situation, professional and cultural differences. A student enrolment programme, implemented through the provision of scholarships, jointly paid by government and industry funds is presented...

  19. The MERLIN programme: Pt. 1

    The MERLIN rig at the Northern Research Laboratories, Springfields, was intended to investigate the deformation behaviour of Zircaloy fuel rod cladding under conditions approximating those of a large break Loss of Coolant Accident (LOCA). In this rig, an assembly of electrically heated fuel rod simulators (6x6 cluster) was subjected to a temperature transient simulating that predicted to occur in a LOCA, including the initiation of bottom reflooding at a suitable stage. The main aim of the MERLIN programme was to investigate the extent of sub-channel blockage produced during clad deformation under conditions of high mechanical restraint, in two phase cooling conditions. The programme was to consist of four test bundles, the final two of which would be used for ballooning experiments in which high sub-channel blockage would be produced by a suitable choice of test conditions. A major part of the programme was to provide validation data for reactor accident codes used in the CEGB clad ballooning safety case for Sizewell B. This report, one of a series which describes the programme in detail, is an overview of the MERLIN programme. It provides background, summarises those reports which discuss the programme in detail and draws attention to those areas where useful information has been obtained. (author)

  20. Neurokinin B-related Peptide Suppresses the Expression of GnRH I, Kiss2 and tac3 in the Brain of Mature Female Nile tilapia Oreochromis niloticus.

    Jin, Ye Hwa; Park, Jin Woo; Kim, Jung-Hyun; Kwon, Joon Yeong

    2016-03-01

    Neurokinin B (NKB) and neurokinin B related peptide (NKBRP) belong to tachykinin peptide family. Theyact as a neurotransmitter and/or neuromodulator. Mutation of NKB and/or its cognate receptor, NK3R resulted in hypogonadotropic hypogonadism in mammals, implying a strong involvement of NKB/NK3R system in controlling mammalian reproduction. Teleosts possess NKBRP as well as NKB, but their roles in fish reproduction need to be clarified. In this study, NKB and NKBRP coding gene (tac3) was cloned from Nile tilapia and sequenced. Based on the sequence, Nile tilapia NKB and NKBRP peptide were synthesized and their biological potencies were tested in vitro pituitary culture. The synthetic NKBRP showed direct inhibitory effect on the expression of GTH subunits at the pituitary level. This inhibitory effect was confirmed in vivo by means of intraperitoneal (ip) injection of synthetic NKB and NKBRP to mature female tilapia (20 pmol/g body weight [BW]). Both NKB and NKBRP had no effect on the plasma level of sex steroids, E2 and 11-KT. However, NKBRP caused declines of expression level of GnRH I, Kiss2 and tac3 mRNAs in the brain while NKB seemed to have no distinct effect. These results indicate some inhibitory roles of NKBRP in reproduction of mature female Nile tilapia, although their exact functions are not clear at the moment. PMID:27294210

  1. AREVA decommissioning strategy and programme

    As with any industrial installation, a nuclear facility has an operating life that requires accounting for its shutdown. In compliance with its sustainable development commitments, AREVA accounts this via its own decommissioning resources to value and make sites fit for further use. These capabilities guarantee the reversibility of the nuclear industry. Thus, the nuclear site value development constitutes an important activity for AREVA, which contributes to the acceptance of nuclear in line with the AREVA continuous policy of sustainable development which is to be fully responsible from the creation, during the operation, to the dismantling of its facilities in all respects with safety, local acceptance and environment. AREVA has already performed a large variety of operation during the life-time of its installations such as heavy maintenance, equipment replacement, upgrading operation. Nowadays, a completely different dimension is emerging with industrial decommissioning operations of nuclear fuel cycle installations: enrichment gaseous diffusion plant, fuel assembly plants, recycling and reprocessing facilities. These activities constitute a major know-how for AREVA. For this reason, the group decided, beginning of 2008, to gather 4 projects in one business unit called Nuclear Site Value Development - a reprocessing plant UP2 400 on AREVA La Hague site, a reprocessing plant UP1 on AREVA Marcoule site, a MOX fuel plant on Cadarache and 2 sites (SICN Veurey and Annecy) that handled GCR fuel fabrication). The main objectives are to enhance the feed back, to contribute to performance improvements, to value professionals and to put innovation forward. The following article will describe in a first part the main decommissioning programmes managed by AREVA NC Nuclear Site Value Development Business Unit. The second part will deal with strategic approaches. A more efficient organization with integration of the supply chain and innovation will be part of the main drivers

  2. Public relations and political support in area-wide integrated pest management programmes that integrate the sterile insect technique

    The public relations component of area-wide integrated pest management (AW-IPM) programmes that integrate the sterile insect technique (SIT) has a large impact on programme success. Full-time professionals should direct public relations activities and secure vital political support from governments and community organizations. Good communication among programme staff, and between programme staff and the public, is required to maintain participation and support, and to keep the work goal-oriented even when some programme activities are controversial. The media can be valuable and effective partners by informing the public about the real facts and activities of a programme, especially if this is done in a non-technical and straightforward way. Ongoing research support improves the programme technology, provides technical credibility on contentious issues, and solves operational problems. Programme failure can result from poor public relations and inadequate public support. (author)

  3. Radiation protection research and training programme review radiation protection programme 1960-89 synopsis of results 1985-89

    This document aims to trace the evolution of the CEC radiation protection programme over its 30 years of existence. During this time, research carried out in the framework of the Community programme has made major contributions to the scientific understanding of the action of ionizing radiation and the protection of man and his environment. This information was crucial for developing better radiation protection management for existing and new technologies and for providing the scientific basis for the regulatory activities of the Commission. One important feature of the programme was the success of bringing together scientists from different Member States to cooperate in the various fields of radiation protection and to integrate different areas of radiation protection research into a coherent approach. The structures thus developed within the programme have enabled research in radiation protection to be conducted in a cost-effective manner on behalf of the Member States. This document aims also to give a synopsis of the most important results of the 1985-89 radiation protection programme. This period was characterized by two challenges, the integration of two Member States into Community research and the impact of the Chernobyl accident. The programme has, in spite of reduced funding, continued to provide a high degree of expertise for the Community in the context of the needs in radiation protection. This has been explicity acknowledged in the evaluation of the 1980-89 programmes carried out by an independent panel

  4. Norwegian mastitis control programme

    Østerås O

    2009-04-01

    changes in attitude and breeding, eradicating bovine virus diarrhoea virus (BVDV and a better implementation of mastitis prevention programmes.

  5. SKIs evaluation of SKBs RD and D programme 92

    Section 11 of the Act (1984:3) on Nuclear Activities stipulates that the holder of a licence to own or operate a nuclear power reactor shall ensure that the necessary comprehensive research and development work is conducted in order to safely handle and finally dispose of the nuclear waste produced and to safely decommission and dismantle installation where the nuclear activity is no longer carried out. According to section 12 of the Act on nuclear activities, the reactor owners shall, in consultation with each other, prepare or have prepared a programme for the necessary comprehensive research and development work and the other measures. The programme shall contain an overview of all measures that may be necessary and also specify, in detail, the measures that are intended to be taken within a period of at least six years. The programme shall be submitted to the Government or to the authority designated by the Government for examination and evaluation. According to section 22 of the ordinance on nuclear activities, the Swedish Nuclear Power Inspectorate (SKI) shall ensure that the research and development work which the reactor owners are responsible for undertaking according to sections 11 and 12 of the act of nuclear activities, is actually carried out. SKIs premise for evaluating the programme has been to examine it as an integrated R and D programme, which essentially focusses on structure, strategy and planning in order to effectively realize the defined goals of the programme, i.e. finding a safe, final solution to the disposal of spent nuclear fuel. Keeping to the time-schedule should not be the controlling factor in carrying out the research and development programme. The essential objective is to attain the goal without jeopardizing quality. SKIs examination has been documented in the form of the following: summary and conclusions, evaluation report, report of comments by reviewing bodies, and consultants reports. SKIs statement to the Government has been

  6. The Hawaii Fruit Fly Area-Wide Pest Management Programme: Influence of a good education and partnerships in a successful programme

    Full text: Introduction: In 1999, USDA-ARS launched the 'Hawaii Fruit Fly Area-Wide Pest Management (AWPM) Program' as a 5-yr programme to suppress fruit flies below economic thresholds while reducing the use of organophosphate insecticides. The programme involved developing and integrating biologically-based pest technologies into a comprehensive management package that will be economically viable, environmentally sensitive and sustainable. Technologies included: 1) field sanitation, 2) protein bait sprays and/or traps, 3) male annihilation with male lures and attractants, and if needed, 4) augmentative parasitoid releases and 5) sterile insect releases. Many of these technologies were developed by ARS in Hawaii; however, they had never been packaged and transferred to Hawaiian farmers. Education: A critical component of successful area-wide pest management (AWPM) programmes is an organised, coordinated and comprehensive outreach educational programme. The Hawaii area-wide fruit fly pest management (HAW-FLYPM) programme's educational programme, utilised the 'logic model' approach to organise, plan, execute and evaluate farmer and community educational programmes statewide. The logic model approach was an outcome-driven rather than activity-based method that employed a linear sequence that developed relationships between programme inputs, outputs and outcomes. This model was utilised extensively to transfer sustainable, science-based technologies to suppress tephritid fruit fly pests. HAW-FLYPM's educational programme targeted growers and community door yard growers, three teaching curricula aimed at elementary through high school students, and a statewide awareness programme for the public at large. Additional key components of the HAWFLYPM education programme was the development of implementation schedules used to track programme progress, a comprehensive media matrix developed to ensure educational materials met the needs of target audience groups, and a

  7. A reappraisal of the virtues of private sector employment programmes

    Jensen, Peter; Graversen, Brian Krogh

    In this paper, we evaluate the employment effects of Danish active labour market programmes aimed at welfare benefit recipients. We estimate an econometric model with treatment effects and discrete outcomes and we allow the responses to treatment to vary among observationally identical persons. The...... empirical analysis is based on a register-based dataset that gives infor-mation on participation in labour market programmes and subsequent employment. Using a latent variable model, we estimate commonly defined treatment effects, and in particular, the distribution of treatment effects. We do not find any...... significant mean effects of participation in private sector employment programmes compared to participation in other programmes, but we find evidence of heterogeneity in the treatment effects....

  8. Emerging regulatory challenges facing the Indian rural electrification programme

    The purpose of this paper is to present and analyse the regulatory issues emerging from the newly launched programme of rural electricity access in India. We focus on two broad areas, namely regulatory issues related to the organisation/structuring of the activities and issues related to subsidy and tariffs. The paper looks into the alternative organisational arrangements being used by the programme and identifies problem areas through a responsibility mapping. The tariff principle being followed by the programme is then analysed considering the alternative organisational forms and issues related to such pricing policies are identified. Possible alternative pricing options are then suggested. The paper finds that while the franchisee model is an innovative idea, it raises issues that the regulators should be concerned with. The programme has so far relied on the simplest franchisee model because of its ease of implementation but a transition to more complex alternatives would require careful considerations. (author)

  9. Emerging regulatory challenges facing the Indian rural electrification programme

    The purpose of this paper is to present and analyse the regulatory issues emerging from the newly launched programme of rural electricity access in India. We focus on two broad areas, namely regulatory issues related to the organisation/structuring of the activities and issues related to subsidy and tariffs. The paper looks into the alternative organisational arrangements being used by the programme and identifies problem areas through a responsibility mapping. The tariff principle being followed by the programme is then analysed considering the alternative organisational forms and issues related to such pricing policies are identified. Possible alternative pricing options are then suggested. The paper finds that while the franchisee model is an innovative idea, it raises issues that the regulators should be concerned with. The programme has so far relied on the simplest franchisee model because of its ease of implementation but a transition to more complex alternatives would require careful considerations

  10. Nuclear power training programmes in Spain

    The introduction of nuclear power in Spain is developing very rapidly. At present 1.1GW(e) are installed in Spain and this is expected to increase to 8GW(e) in 1980 and to 28GW(e) in 1990. Spanish industry and technology are also rapidly increasing their participation in building nuclear stations, in manufacturing the necessary components and in the activities related to the nuclear fuel cycle. All of this requires properly trained personnel, which is estimated to become approximately 1200 high-level technicians, 1100 medium-level technicians and 1500 technical assistants by 1980. This personnel is trained: (a) in engineering schools; (b) in the Nuclear Studies Institute; (c) in the electric companies with nuclear programmes. The majority of the high-level engineering schools in the country include physics and basic nuclear technology courses in their programmes. Some of them have an experimental low-power nuclear reactor. The Nuclear Studies Institute is an official organism dependent on the Nuclear Energy Commission and responsible, among other subjects, for training personnel for the peaceful use and development of nuclear energy in the country. The electric companies also participate in training personnel for future nuclear stations and they plan to have advanced simulators of PWR and BWR type stations for operator training. The report deals with the personnel requirement forecasts and describes the training programmes. (author)

  11. Molecular laser isotope separation programme at BARC

    Little over thirty years ago, BARC ventured into a new frontier of scientific research: Molecular Laser Isotope Separation (MLIS) programme based on the interaction of lasers with molecules. The initial project was a scheme to produce enriched uranium. The idea was to use the intense, monochromatic light of lasers to break the chemical bonds of only those molecules containing the fissionable isotope uranium-235. At present the programme is evolving around separation of low and middle mass isotopes, namely sulphur 34/33/32, oxygen 17/18, carbon 13/12, hydrogen T/D/H to be followed by an advanced engineering programme designed to lead to a demonstration plant. The latest results have come very close to the design parameters specified for a full-scale separation of carbon isotopes. All these expertise provide an infra structure for future front line R and D activities in the general area of Laser Photochemical Technology which would include i) LIS of other useful elements ii) Material processing and iii) Fuel reprocessing/ waste management (author)

  12. IAEA occupational radiation protection programme: current status

    As stated in Art.III.A.6 of its Statute, the International Atomic Energy Agency (commonly referred to as the Agency) is authorized to establish or adopt, in consultation and, where appropriate, in collaboration with the competent organs of the United Nations and with the specialized agencies concerned, standards of safety for protection of health and minimization of danger to life and property (including such standards for labour conditions), and to provide for the application of these standards to its own operation as well as to the operations making use of materials, services, equipment, facilities, and information made available by the Agency or at its request or under its control or supervision. The Agency s Occupational Radiation Protection Programme aims at harmonizing infrastructures for the control of radiation exposure of workers and for optimizing radiation protection in situation s of exposures due to external radiation and intakes of radionuclides from both artificial and natural sources of radiation. Under its regular and technical cooperation programmes, the Agency has been assigning high priority to both the establishment of safety standards for labour conditions and for the application of these standards through, Interalia, direct assistance under its technical cooperation (TC) programme, the rendering of services, the promotion of education and training, the fostering of information exchange and the coordination of research and development. The purpose of this paper is to present the current status and future IAEA activities in support of occupational radiation protection. (authors)

  13. The Learning Effects of a Multidisciplinary Professional Development Programme

    Visser, Talitha Christine; Coenders, Fer G. M.; Pieters, Jules M.; Terlouw, Cees

    2013-12-01

    Professional development becomes relevant and effective when teachers are actively involved, collaborate, and when it is linked to teachers' daily school practice (Hunzicker in Prof Dev Educ 37:177-179, 2011). Preparation of teachers for a curriculum implementation such as the new subject Nature, Life, and Technology can be done by a professional development programme where teachers are actively involved (Visser et al. 2010). This study evaluates the designed and implemented professional development programme with respect to its effectiveness in terms of degree of teacher learning and development. Effects are evaluated for five learning areas: Instructional strategies, differences in students' prior knowledge, adjustments to the module, assessment methods and instruments, and field trips and guest lectures. Eleven teachers from four different schools participated in two professional development programmes, six teachers in the first professional development programme and five teachers in the programme for the subsequent module. Questionnaires and interviews were used to assess the effects in the different learning areas. The findings show that the professional development programme is a useful venture for teachers' professional growth in different learning areas.

  14. Parent involvement when developing health education programmes

    Holger Hassel

    2008-03-01

    Full Text Available

    Background: The problem of obesity in children and adults has been widely recognised and described in the literature [1]. There are several challenges leading to an augmentation of the problem. Firstly, the aetiology of overweight and obesity is not clear. Secondly, the long term effectiveness of prevention programmes is low. Only in some groups and for a short period of time an effect may be visible [2]. Thirdly, little is known about what children should learn when [3]. A proper concept of educating children in regard to healthy eating or physical activity does not exist. As far as we know an essential pre-requisite for health education programmes is that they are lifestyleoriented and easily transferable into daily family life [4]. For this, working together with the parents would be essential. The main goal of this article will be 1 to get a better understanding of what parents and nurses/ teachers want 2 to strengthen the point that this method is one way to involve the target groups and thus it is likely to increase the acceptance of health education programmes 3 to describe that focus group discussions are a useful tool to identify the opinions of the target group.

    Methods: In the frame of three projects, focus groups with nurses/ teachers and parents have been carried out.

    Results and Conclusions: Results from different focus group discussions with pedagogues and parents will be discussed and conclusions for health education programmes relevant to all key players involved will be identified.

  15. Training in radiological protection for nuclear programmes

    Many Member States are developing or already have developed their own national training programmes. The IAEA is actively involved in promoting training in radiological protection for nuclear programmes. The various types of training are fully discussed, with suggested curricula. An earlier report was published as Technical Reports Series No.31 in 1964. In 1973, new and additional information was received from Member States which is reflected in the present report. Training programmes are classified, according to those requiring training: specialists; persons whose work is closely related to radiological protection (administrators, public health officers and industrial health personnel, safety inspectors and engineers in nuclear installations, public service personnel); persons working with radiation; and the general public. Forms, scope and duration of training are discussed. Different types of training programmes are currently required for training of medical doctors (those providing medical surveillance for radiation workers and others dealing with public health aspects of radiation hazards), for technical supervisors, radiologists, and qualified workers in nuclear medicine, technological staff, administrators, persons working with radiation, and public service personnel. Standard curricula and desirable experiments and exercises are discussed. The organization of training together with the facilities, equipment and teaching staff required are considered, as is follow-up training. Annexes 1 to 4 give examples of training curricula and training courses available in various countries, a suggested syllabus for training of technical supervisors, and a bibliography consisting of 210 references dealing with general topics, nuclear radiation physics, radiochemistry and radiation chemistry, radiation biology and biophysics, dosimetry and health physics and radiation protection, medical aspects and toxicology, and environmental aspects

  16. NDA National Graduate Programme 'nucleargraduates'

    The aim of this paper is to outline the NDA National Graduate Programme (nuclear graduates). The NDA has a remit under the Energy Act (2004) 'to maintain and develop the skills for decommissioning and nuclear clean-up'. Although current research is now being reviewed, there is significant evidence to suggest that the age profile in the Site Licence Companies is skewed towards older workers and there is likely to be a skill shortage in 3-5 years. As nuclear clean-up is a national issue; skill shortages also become a national issue in a very real sense. In addition, evidence suggests that the industry needs to be constantly challenged in order to achieve its targets for decommissioning. The NDA has a unique position under the Act. It is both a strategic overseer and direct employer. To this end the 'National Graduate Programme' is aligned to both the NDA's previous succession plans and the needs of the industry. Industry needs leadership that challenges the status quo and moves the UK nuclear industry to become best in class; Industry needs a dedicated to programme to address skills shortages and difficult to recruit areas such as, but not exclusively, estimators, schedulers, contract managers, site engineers, decommissioning technicians, safety monitors; The NDA has indicated a 'commercial and politically savvy' cohort is required to meet its own internal challenges and to ensure sustainability in its own workforce, and to be sensitive to the needs of customers and suppliers alike; Need to create a more diversified workforce in the nuclear industry and also plan for new skills evolving from research and development breakthroughs; Need to ensure that Tier 1, 2, 3 and 4 contractors invest in the leadership and skills for the future. World Class - delivery will be benchmarked against UK based multinational companies who operate in a global graduate attraction and development marketplace. The graduates targeted will be from leading institutions and will have a blend of

  17. Europe's space photovoltaics programme

    Bogus, Klaus P.

    1994-01-01

    The current space PV (photovoltaic) technology development program of ESA is described. The program is closely coupled to the European space mission scenario for the next 10 year period and has as its main objective to make the most effective use of the limited resources available for technology in the present economical climate. This requires a well-balanced approach between concentration on very few options and keeping the competition alive if more than one promising technology exists. The paper describes ESA's main activities in the areas of solar array technology, solar cell technology, solar cell assembly technology, and special test and verification activities including the in-orbit demonstration of new technologies.

  18. Attendance in cancer screening programmes in Italy

    Grazia Grazzini

    2008-06-01

    Full Text Available

    Background: The European Community recommends mammography, cervical and colorectal cancer screening programmes. In Italy, cancer screening programmes have been included in the Basic Healthcare Parameters (Livelli Essenziali di Assistenza since 2001. Full national coverage of a population-based organized screening programme has been planned for in Italy and is being implemented. Since 2005, the Ministry of Health - Department of Prevention has formally charged The National Centre for Screening Monitoring (Osservatorio Nazionale Screening –ONS- with monitoring and promoting screening programmes nationwide. Participation of target populations is a key indicator of the impact and efficacy of a screening programme in reducing cancer mortality.

    Methods: Attendance of invitees is one of the indicators calculated every year in the quality control of Italian screening programmes. Data collection is organized by means of a structured questionnaire, sent by ONS to the referent for data collection in each Region, who then returns the completed questionnaires to the Regional Centre. Questionnaires are then sent to the National Centre. Logical and epidemiologic checks are performed at both levels. Every year ONS publishes reports on the results of the surveys. A feasibility study for a National data warehouse based on individual records is in progress. The national survey “Multiscopo sulle famiglie” and the Passi Study (Progetti delle Aziende Sanitarie per la Salute in Italia provided additional information regarding spontaneous preventive health care activities in the Italian population.

    Results: Mammography screening: In 2006, 78.2% of Italian women aged 50-69 lived in areas where organised screening was in place (theoretical extension, however, the distribution of the screening activity is not uniform (higher in Northern/Central Italy compared with Southern

  19. Evaluation of the FWF Doctoral Programme (DK Programme)

    Ecker, Brigitte; Kottmann, Andrea; Meyer, Susanne; Brandl, Bianca

    2014-01-01

    In the winter term 2013 a total of 27,634 doctoral students were enrolled at Austrian universities and a total of 2,165 students obtained a doctoral degree; thereof 204 (9.4%) students graduated in a PhD Programme. In total 7,158 doctoral students were employed at Austrian universities in 2012. These numbers include those doctoral students with temporary positions who were funded by competitive means, as provided by the funding programmes of the FWF. In total the FWF as the most important fun...

  20. Programmable automation systems in PSA

    The Finnish safety authority (STUK) requires plant specific PSAs, and quantitative safety goals are set on different levels. The reliability analysis is more problematic when critical safety functions are realized by applying programmable automation systems. Conventional modeling techniques do not necessarily apply to the analysis of these systems, and the quantification seems to be impossible. However, it is important to analyze contribution of programmable automation systems to the plant safety and PSA is the only method with system analytical view over the safety. This report discusses the applicability of PSA methodology (fault tree analyses, failure modes and effects analyses) in the analysis of programmable automation systems. The problem of how to decompose programmable automation systems for reliability modeling purposes is discussed. In addition to the qualitative analysis and structural reliability modeling issues, the possibility to evaluate failure probabilities of programmable automation systems is considered. One solution to the quantification issue is the use of expert judgements, and the principles to apply expert judgements is discussed in the paper. A framework to apply expert judgements is outlined. Further, the impacts of subjective estimates on the interpretation of PSA results are discussed. (orig.) (13 refs.)