Effect of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function.

Science.gov (United States)

Takasu, Toshiyuki; Ukai, Masashi; Sato, Shuichi; Matsui, Tetsuo; Nagase, Itsuro; Maruyama, Tatsuya; Sasamata, Masao; Miyata, Keiji; Uchida, Hisashi; Yamaguchi, Osamu

2007-05-01

We evaluated the pharmacological characteristics of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]-ethyl} acetanilide (YM178). YM178 increased cyclic AMP accumulation in Chinese hamster ovary (CHO) cells expressing human beta3-adrenoceptor (AR). The half-maximal effective concentration (EC50) value was 22.4 nM. EC50 values of YM178 for human beta1- and beta2-ARs were 10,000 nM or more, respectively. The ratio of intrinsic activities of YM178 versus maximal response induced by isoproterenol (nonselective beta-AR agonist) was 0.8 for human beta3-ARs, 0.1 for human beta1-ARs, and 0.1 for human beta2-ARs. The relaxant effects of YM178 were evaluated in rats and humans bladder strips precontracted with carbachol (CCh) and compared with those of isoproterenol and 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one hydrochloride (CGP-12177A) (beta3-AR agonist). EC50 values of YM178 and isoproterenol in rat bladder strips precontracted with 10(-6) M CCh were 5.1 and 1.4 microM, respectively, whereas those in human bladder strips precontracted with 10(-7) M CCh were 0.78 and 0.28 microM, respectively. In in vivo study, YM178 at a dose of 3 mg/kg i.v. decreased the frequency of rhythmic bladder contraction induced by intravesical filling with saline without suppressing its amplitude in anesthetized rats. These findings suggest the suitability of YM178 as a therapeutic drug for the treatment of symptoms of overactive bladder such as urinary frequency, urgency, and urge incontinence.

Generating functional and large N limit of nonlocal 2D generalized Yang-Mills theories (nlgYM2's)

International Nuclear Information System (INIS)

Saaidi, K.; Sajadi, H.M.

2001-01-01

Using the path integral method, we calculate the partition function and the generating functional (of the field strengths) on nonlocal generalized 2D Yang-Mills theories (nlgYM 2 's), which are nonlocal in the auxiliary field. This has been considered before by Saaidi and Khorrami. Our calculations are done for general surfaces. We find a general expression for the free energy of W(φ) =φ 2k in nlgYM 2 theories at the strong coupling phase (SCP) regime (A > A c ) for large groups. In the specific φ 4 model, we show that the theory has a third order phase transition. (orig.)

Geometric approach to the (BRS-) differential algebras of supersymmetric YM-theories

International Nuclear Information System (INIS)

Gieres, F.

1987-01-01

The (BRS-) differential algebra of susy YM-theories is defined in terms of superfields and forms on rigid U(N)-superspace. For d = 4 and N = 1.2 we show that it projects to the ''BRS-component field algebra in the WZ-gauge'' without any supergauge fixing. In this process the supergeometry is destroyed with the result that the final algebra becomes a prototype for a differential algebra which cannot be associated with an ordinary Lie algebra

DOI - Digital Object Identifier : A revolution in the management and trading of copyrighted information over the Internet in the third millenium

Directory of Open Access Journals (Sweden)

Martin Žnideršič

1997-01-01

Full Text Available Rapid development of information technology in recent years has brought over also the problem of the protection of author's rights related to copyrighted works on electronic media. Information and law specialists were intensively working on this problem for several years and the result has been a new system of labelling copyrighted works on the Internet, called DOI (Digitial Object Identifier. The system was developed in the United States. At the time of the presenta tion of DOI at the Bookfair in Frankfurt, 250.000 author works were labelled with DOI. The system is universal and enables the inclusion of the present standard identifiers (ISBN, ISSN, SICI. The fact that DOI identifier stays "glued on" forever, makes the identification of the carrier of copyright possible at any moment. The DOI system presents the infrastructure system for trading in and use of copyrighted works over the Internet in the third millenium.

An antifungal compound produced by Bacillus subtilis YM 10-20 inhibits germination of Penicillium roqueforti conidiospores

NARCIS (Netherlands)

Chitarra, G.S.; Breeuwer, P.; Nout, M.J.R.; Aelst, van A.C.; Rombouts, F.M.; Abee, T.

2003-01-01

Aims: To identify and characterize an antifungal compound produced by Bacillus subtilis YM 10-20 which prevents spore germination of Penicillium roqueforti . Methods and Results: The antifungal compound was isolated by acid precipitation with HCl. This compound inhibited fungal germination and

Nitrogen-containing bisphosphonate, YM529/ONO-5920 (a novel minodronic acid), inhibits RANKL expression in a cultured bone marrow stromal cell line ST2

International Nuclear Information System (INIS)

Nishida, Shozo; Tsubaki, Masanobu; Hoshino, Mayumi; Namimatsu, Ayumi; Uji, Hiromi; Yoshioka, Shohei; Tanimori, Yoshihiro; Yanae, Masashi; Iwaki, Masahiro; Irimajiri, Kiyohiro

2005-01-01

Increase in bone resorption by osteoclasts can cause metabolic bone diseases, such as osteoporosis. Recent attention has been paid to the receptor activator of the NF-κB ligand (RANKL), an accelerator of osteoclast differentiation. RANKL is expressed on the bone marrow-derived stromal cell membrane and induces the differentiation of osteoclasts by binding to RANK expressed on the osteoclast precursor cell membrane. Since the inhibition of RANKL expression can lead to the inhibition of osteoclastic bone resorption, the clinical application of RANKL inhibition could be expected to have a major effect on metabolic bone disease therapy. In this study, we investigated whether or not YM529/ONO-5920, a nitrogen-containing bisphosphonate (a novel minodronic acid), inhibits RANKL expression in a bone marrow-derived stromal cell line (ST2 cells). Reverse transcription-polymerase chain reaction revealed that the administration of YM529/ONO-5920 to ST2 cells inhibited RANKL mRNA expression and reduced RANKL proteins as assessed by Western blot analysis. The inhibition of RANKL mRNA expression was reversed when geranylgeranyl pyrophosphate (GGPP), an intermediate in the mevalonate pathway, was used in combination. Furthermore, YM529/ONO-5920 reduced phosphorylated extracellular signal-regulated kinase 1/2 (ERK1/2), and similarly, U0126, a mitogen-activated protein kinase kinase 1/2 inhibitor, inhibited RANKL expression. Pretreatment with GGPP reversed the YM529/ONO-5920-induced decrease in phosphorylation of ERK. Furthermore, YM529/ONO-5920 decreased TRAP-positive cells in co-culture of ST2 cells and an osteoclast cell line, C7 cells, and this decrease was inhibited by pretreatment with GGPP. This indicates that YM529/ONO-5920 inhibits GGPP biosynthesis in the mevalonate pathway and then signal transduction in the Ras-mitogen-activated protein kinase pathway, thereby inhibiting RANKL expression on ST2 cells. These results suggest a newly elucidated action of bisphosphonates in

Structure-Activity Relationship Studies of the Cyclic Depsipeptide Natural Product YM-254890, Targeting the Gq Protein

DEFF Research Database (Denmark)

Zhang, Hang; Xiong, Xiao-feng; Boesgaard, Michael W

2017-01-01

that specifically inhibit signaling mediated by the Gq subfamily. In this study we exploit a newly developed synthetic strategy for this compound class in the design, synthesis, and pharmacological evaluation of eight new analogues of YM-254890. These structure-activity relationship studies led to the discovery...

Characterization and emulsifying property of a novel bioemulsifier by Aeribacillus pallidus YM-1.

Science.gov (United States)

Zheng, C; Li, Z; Su, J; Zhang, R; Liu, C; Zhao, M

2012-07-01

  Biosurfactants and bioemulsifiers commonly have the advantages of biodegradability, low toxicity, selectivity and biocompatibility over chemically synthesized surfactants. The goal of the study is to present a novel bioemulsifier with great application potential.   Aeribacillus pallidus YM-1, isolated from crude oil contaminated soil, was found to produce a novel high molecular bioemulsifier with an emulsification index of 60 ± 1% without remarkable surface tension reduction (45·7 ± 0·1 mN m(-1) ). The number-average molecular weight was determined as 526 369 Da by gel permeation chromatography analysis. Bioemulsifier was subjected to FT-IR and a complex of carbohydrates (41·1%), lipids (47·6%) and proteins (11·3%) was determined.   The bioemulsifier of A. pallidus YM-1 was isolated from the glucose-based culture medium and characterized with the help of chemical analytical techniques. The bioemulsifier exhibited a promising emulsifying property for biotechnology application potential in bioremediation and microbial enhanced oil recovery.   This is the first report of the bioemulsifier production by A. pallidus. The potential emulsifying activity of the bioemulsifier in the present study may be explored in various biotechnological and industrial applications. © 2012 The Authors. Journal of Applied Microbiology © 2012 The Society for Applied Microbiology.

Comparative genome analysis identifies two large deletions in the genome of highly-passaged attenuated Streptococcus agalactiae strain YM001 compared to the parental pathogenic strain HN016.

Science.gov (United States)

Wang, Rui; Li, Liping; Huang, Yan; Luo, Fuguang; Liang, Wanwen; Gan, Xi; Huang, Ting; Lei, Aiying; Chen, Ming; Chen, Lianfu

2015-11-04

Streptococcus agalactiae (S. agalactiae), also known as group B Streptococcus (GBS), is an important pathogen for neonatal pneumonia, meningitis, bovine mastitis, and fish meningoencephalitis. The global outbreaks of Streptococcus disease in tilapia cause huge economic losses and threaten human food hygiene safety as well. To investigate the mechanism of S. agalactiae pathogenesis in tilapia and develop attenuated S. agalactiae vaccine, this study sequenced and comparatively analyzed the whole genomes of virulent wild-type S. agalactiae strain HN016 and its highly-passaged attenuated strain YM001 derived from tilapia. We performed Illumina sequencing of DNA prepared from strain HN016 and YM001. Sequencedreads were assembled and nucleotide comparisons, single nucleotide polymorphism (SNP) , indels were analyzed between the draft genomes of HN016 and YM001. Clustered regularly interspaced short palindromic repeats (CRISPRs) and prophage were detected and analyzed in different S. agalactiae strains. The genome of S. agalactiae YM001 was 2,047,957 bp with a GC content of 35.61 %; it contained 2044 genes and 88 RNAs. Meanwhile, the genome of S. agalactiae HN016 was 2,064,722 bp with a GC content of 35.66 %; it had 2063 genes and 101 RNAs. Comparative genome analysis indicated that compared with HN016, YM001 genome had two significant large deletions, at the sizes of 5832 and 11,116 bp respectively, resulting in the deletion of three rRNA and ten tRNA genes, as well as the deletion and functional damage of ten genes related to metabolism, transport, growth, anti-stress, etc. Besides these two large deletions, other ten deletions and 28 single nucleotide variations (SNVs) were also identified, mainly affecting the metabolism- and growth-related genes. The genome of attenuated S. agalactiae YM001 showed significant variations, resulting in the deletion of 10 functional genes, compared to the parental pathogenic strain HN016. The deleted and mutated functional genes all

Czech language style of television advertising of the new millenium on the example of the T-Mobile's media campaign

OpenAIRE

Steklá, Kateřina

2015-01-01

Czech language style of television advertising of the new millenium on the example of the T-Mobile's media campaign This bachelor thesis deals with the contemporary language style of Czech advertising on the example of brand communication/ advertising campaign of T-Mobile. The work is divided into two parts: theoretical and practical. The theoretical block introduces the context of advertising and shows the characteristics of advertising messages and language of advertising discourse. The foc...

Density functional theory and surface reactivity study of bimetallic AgnYm (n+m = 10) clusters

Science.gov (United States)

Hussain, Riaz; Hussain, Abdullah Ijaz; Chatha, Shahzad Ali Shahid; Hussain, Riaz; Hanif, Usman; Ayub, Khurshid

2018-06-01

Density functional theory calculations have been performed on pure silver (Agn), yttrium (Ym) and bimetallic silver yttrium clusters AgnYm (n + m = 2-10) for reactivity descriptors in order to realize sites for nucleophilic and electrophilic attack. The reactivity descriptors of the clusters, studied as a function of cluster size and shape, reveal the presence of different type of reactive sites in a cluster. The size and shape of the pure silver, yttrium and bimetallic silver yttrium cluster (n = 2-10) strongly influences the number and position of active sites for an electrophilic and/or nucleophilic attack. The trends of reactivities through reactivity descriptors are confirmed through comparison with experimental data for CO binding with silver clusters. Moreover, the adsorption of CO on bimetallic silver yttrium clusters is also evaluated. The trends of binding energies support the reactivity descriptors values. Doping of pure cluster with the other element also influence the hardness, softness and chemical reactivity of the clusters. The softness increases as we increase the number of silver atoms in the cluster, whereas the hardness decreases. The chemical reactivity increases with silver doping whereas it decreases by increasing yttrium concentration. Silver atoms are nucleophilic in small clusters but changed to electrophilic in large clusters.

The evolution of the Y-M scaling relation in MUSIC clusters

Science.gov (United States)

Sembolini, F.; Yepes, G.; De Petris, M.; Gottlöber, S.; Lamagna, L.; Comis, B.

2013-04-01

This work describes the baryon content and Sunyaev-Zeld'ovich properties of the MUSIC (Marenostrum-MultiDark SImulations of galaxy clusters) dataset and their evolution with redshift and aperture radius. The MUSIC dataset is one of the largest samples of hydrodynamically simulated galaxy clusters (more than 2000 objects, including more than 500 clusters). We show that when the effects of cooling and stellar feedbacks are properly taken into account, the gas fraction of the MUSIC clusters consistently agrees with recent observational results. Moreover, the gas fraction has a net dependence with the total mass of the cluster and increases slightly with redshift at high overdensities. The study of the Y-M relation confirms the consistence of the self-similar model, showing no evolution with redshift at low overdensities.

The small molecule survivin inhibitor YM155 may be an effective treatment modality for colon cancer through increasing apoptosis

Energy Technology Data Exchange (ETDEWEB)

Li, Wan Lu, E-mail: lvvlchina@msn.cn [Department of Pathology, Yonsei University Wonju College of Medicine, Wonju (Korea, Republic of); Lee, Mi-Ra, E-mail: mira1125@yonsei.ac.kr [Department of Pathology, Yonsei University Wonju College of Medicine, Wonju (Korea, Republic of); Cho, Mee-Yon, E-mail: meeyon@yonsei.ac.kr [Department of Pathology, Yonsei University Wonju College of Medicine, Wonju (Korea, Republic of); Institute of Genomic Cohort, Yonsei University Wonju College of Medicine, Wonju (Korea, Republic of)

2016-03-04

Survivin has a known beneficial role in the survival of both cancer cells and normal cells. Therapies targeting survivin have been proposed as an alternative treatment modality for various tumors; however, finding the proper indication for this toxic therapy is critical for reducing unavoidable side effects. We recently observed that high survivin expression in CD133{sup +} cells is related to chemoresistance in Caco-2 colon cancer cells. However, the effect of survivin-targeted therapy on CD133{sup +} colon cancer is unknown. In this study, we investigated the roles of CD133 and survivin expression in colon cancer biology in vitro and comparatively analyzed the anticancer effects of survivin inhibitor on CD133{sup +} cells (ctrl-siRNA group) and small interfering RNA (siRNA)-induced CD133{sup −} cells (CD133-siRNA group) obtained from a single colon cancer cell line. CD133 knockdown via siRNA transfection did not change the tumorigenicity of cells, although in vitro survivin expression levels in CD133{sup +} cells were higher than those in siRNA-induced CD133{sup −} cells. The transfection procedure seemed to induce survivin expression. Notably, a significant number of CD133{sup −} cells (33.8%) was found in the cell colonies of the CD133-siRNA group. In the cell proliferation assay after treatment, YM155 and a combination of YM155 and 5-fluorouracil (5-FU) proved to be far more effective than 5-FU alone. A significantly increased level of apoptosis was observed with increasing doses of YM155 in all groups. However, significant differences in therapeutic effect and apoptosis among the mock, ctrl-siRNA, and CD133-siRNA groups were not detected. Survivin inhibitor is an effective treatment modality for colon cancer; however, the role of CD133 and the use of survivin expression as a biomarker for this targeted therapy must be verified.

The small molecule survivin inhibitor YM155 may be an effective treatment modality for colon cancer through increasing apoptosis

International Nuclear Information System (INIS)

Li, Wan Lu; Lee, Mi-Ra; Cho, Mee-Yon

2016-01-01

Survivin has a known beneficial role in the survival of both cancer cells and normal cells. Therapies targeting survivin have been proposed as an alternative treatment modality for various tumors; however, finding the proper indication for this toxic therapy is critical for reducing unavoidable side effects. We recently observed that high survivin expression in CD133"+ cells is related to chemoresistance in Caco-2 colon cancer cells. However, the effect of survivin-targeted therapy on CD133"+ colon cancer is unknown. In this study, we investigated the roles of CD133 and survivin expression in colon cancer biology in vitro and comparatively analyzed the anticancer effects of survivin inhibitor on CD133"+ cells (ctrl-siRNA group) and small interfering RNA (siRNA)-induced CD133"− cells (CD133-siRNA group) obtained from a single colon cancer cell line. CD133 knockdown via siRNA transfection did not change the tumorigenicity of cells, although in vitro survivin expression levels in CD133"+ cells were higher than those in siRNA-induced CD133"− cells. The transfection procedure seemed to induce survivin expression. Notably, a significant number of CD133"− cells (33.8%) was found in the cell colonies of the CD133-siRNA group. In the cell proliferation assay after treatment, YM155 and a combination of YM155 and 5-fluorouracil (5-FU) proved to be far more effective than 5-FU alone. A significantly increased level of apoptosis was observed with increasing doses of YM155 in all groups. However, significant differences in therapeutic effect and apoptosis among the mock, ctrl-siRNA, and CD133-siRNA groups were not detected. Survivin inhibitor is an effective treatment modality for colon cancer; however, the role of CD133 and the use of survivin expression as a biomarker for this targeted therapy must be verified.

The prospects of natural gas at the threshold of the third millenium and the search of new equilibria

International Nuclear Information System (INIS)

Valais, M.

1992-01-01

Between growing and abundant resources and the promise of increasingly open potential markets, natural gas may seem a providential source of energy for the next decades and moreover one which may more easily answer new demands of environmental protection. However, this perspective of expansion is not without constraints. Progressively, the development of natural gas encounters heavier and heavier logistical and infrastructural needs, increasingly costly at all stages of its industrial chain. The industry of natural gas should necessarily find answers, new balances between the market prices and the cost of future supplies, in order to assure the continuation of its expansion well beyond the end of the present millenium. 3 refs., 5 figs

Adventures of the coupled Yang-Mills oscillators: II. YM-Higgs quantum mechanics

International Nuclear Information System (INIS)

Matinyan, Sergei G; Mueller, Berndt

2006-01-01

We continue our study of the quantum mechanical motion in the x 2 y 2 potentials for n = 2, 3, which arise in the spatially homogeneous limit of the Yang-Mills (YM) equations. In the present paper, we develop a new approach to the calculation of the partition function Z(t) beyond the Thomas-Fermi (TF) approximation by adding a harmonic (Higgs) potential and taking the limit v → 0, where v is the vacuum expectation value of the Higgs field. Using the Wigner-Kirkwood method to calculate higher-order corrections in ℎ, we show that the limit v → 0 leads to power-like singularities of the type v -n , which reflect the possibility of escape of the particle along the channels in the classical limit. We show how these singularities can be eliminated by taking into account the quantum fluctuations dictated by the form of the potential

RUBY-1: a randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome

DEFF Research Database (Denmark)

Steg, Ph Gabriel; Mehta, Shamir R; Jukema, J Wouter

2011-01-01

To establish the safety, tolerability and most promising regimen of darexaban (YM150), a novel, oral, direct factor Xa inhibitor, for prevention of ischaemic events in acute coronary syndrome (ACS)....

Mega-rings Surrounding Timber Mountain Nested Calderas, Geophysical Anomalies: Rethinking Structure and Volcanism Near Yucca Mountain (YM), Nevada

Science.gov (United States)

Tynan, M. C.; Smith, K. D.; Savino, J. M.; Vogt, T. J.

2004-12-01

Observed regional mega-rings define a zone ˜80-100 km in diameter centered on Timber Mountain (TM). The mega-rings encompass known smaller rhyolitic nested Miocene calderas ( ˜11-15 my, structural relationships. Mega-rings consist of arcuate faulted blocks with deformation (some remain active structures) patterns showing a genetic relationship to the TM volcanic system; they appear to be spatially associated and temporally correlated with Miocene volcanism and two geophysically identified crustal/upper mantle features. A 50+ km diameter pipe-like high velocity anomaly extends from crustal depth to over 200 km beneath TM (evidence for 400km depth to NE). The pipe is located between two ˜100 km sub-parallel N/S linear trends of small-magnitude earthquake activity, one extending through the central NV Test Site, and a second located near Beatty, NV. Neither the kinematics nor relational mechanism of 100km seismically active N/S linear zones, pipe, and mega-rings are understood. Interpreted mega-rings are: 1) Similar in size to larger terrestrial volcanic complexes (e.g., Yellowstone, Indonesia's Toba system); 2) Located in the region of structural transition from the Mohave block to the south, N/S Basin and Range features to the north, Walker Lane to the NW, and the Las Vegas Valley shear zone to the SE; 3) Associated with the two seismically active zones (similar to other caldera fault-bounded sags), the mantle high velocity feature, and possibly a regional bouguer gravity anomaly; 4) Nearly coincident with area hydrologic basins and sub-basins; 5) Similar to features described from terrestrial and planetary caldera-collapse studies, and as modeled in laboratory scaled investigations (ice melt, balloon/sand). Post Mid-Miocene basalts commonly occur within or adjacent to the older rhyolitic caldera moats; other basaltic material occurs marginal to both the outer rings of the interpreted mega-ring system and high velocity pipe. The YM repository may be situated in

Effects of (-)-S-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro[4,5]decane L-tartrate monohydrate (YM796), a novel muscarinic agonist, on disturbance of passive avoidance learning behavior in drug-treated and senescence-accelerated mice.

Science.gov (United States)

Suzuki, M; Yamaguchi, T; Ozawa, Y; Ohyama, M; Yamamoto, M

1995-11-01

Effects of YM796 (-)-S-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro[4,5]decane L-tartrate monohydrate; a novel muscarinic agonist, were observed on disturbance of passive avoidance learning behavior in drug- (protein synthesis inhibitor and anticholinergic drugs) treated and senescence-accelerated mice in comparison with those of a muscarinic agonist (AF102B) and acetylcholinesterase inhibitors (E2020 (1-benzyl-4-[(5,6-dimethoxy-1-indanone-2-yl) methyl] piperidene hydrochloride), NIK247 [9-amino-2,3,5,6,7,8-hexahydro-1H-cyclopenta(b)-quinoline monohydrate hydrochloride], THA (9-amino-1,2,3,4-tetrahydroacridine) and physostigmine). All tested drugs administered before training significantly prolonged the shortened latency of step-through induced by the protein synthesis inhibitor cycloheximide (150 mg/kg s.c.). This shortened latency was also significantly prolonged when YM796 was administered immediately after training, but not when administered before the test trial. The ameliorating effect of YM796 on the impairment in learning behavior by cycloheximide was significantly suppressed by pirenzepine (0.1 micrograms/mouse i.c.v.). When administered before training, all test drugs prolonged the shortened latency of step-through induced by treatment with the anticholinergic drugs [scopolamine (1 mg/kg s.c.) and hemicholinium-3 (0.3 microgram/mouse i.c.v.)], suggesting that they ameliorated the impairment of learning behavior. This shortened latency in scopolamine-treated mice was also significantly prolonged by YM796, AF102B, E2020, NIK247 and physostigmine when administered immediately after training, but not when administered before the test trial. The pharmacological actions of YM796 administered immediately after training and before the test trial in hemicholinium-3-treated mice were similar to those in scopolamine-treated mice.(ABSTRACT TRUNCATED AT 250 WORDS)

THE PROBLEM OF THE FEASIBILITY STUDY IN RESPECT OF DESIGN OF JOINTS OF METAL STRUCTURES

Directory of Open Access Journals (Sweden)

Morozova Dina Vol'demarovna

2012-12-01

It is noteworthy that this problem enjoyed much attention back in the past when the country suffered from steel deficit, and metal processing plants could not keep up with the needs of consumers. This problem was dealt with by Y.M. Lihtarnikov, a Soviet scientist, who published his work "Variant design and optimization of steel structures" in 1979. The authors employ the theoretical base developed by the scientist to perform their research into the optimum solutions to the problems of several types of metal joints.

Missing Millions and Measuring Progress towards the Millenium Development Goals with a focus on Central Asian States

Directory of Open Access Journals (Sweden)

Roy Carr-Hill

2012-07-01

Full Text Available Background In developing countries, population estimates and assessments of progress towards the Millenium Development Goals are based increasingly on household surveys.  It is not recognised that they are inappropriate for obtaining information about the poorest of the poor..  This is because they, typically, omit by design: those not in households because they are homeless; those who are in institutions; and mobile, nomadic or pastoralist populations.  In addition, in practice, because they are difficult to reach, household surveys will typically under-represent: those in fragile, disjointed or multiple occupancy households; those in urban slums, and may omit certain areas of a country deemed to pose a security risk. Those six sub-groups constitute a pretty comprehensive ostensive definition of the ‘poorest of the poor’. Methods This paper documents these omissions in general, drawing on worldwide literature about the theory and practice fo implementing censuses and household surveys; and shows how substantial proportions are missing from both censuses and the sample frames of surveys. Results This paper suggests that between 300 and 350 million will effectively be missed worldwide from the sampling frames of such surveys and from most censuses.  The impact on the health MDGs is illustrated for the five republics of the former Soviet Union making up Central Asia: Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan and Uzbekistan Conclusions It is impossible to assess progress towards or away from the MDGS in both the Central Asian Republics and worldwide.  It is urgent to find solutions to the problem of the ‘missing ‘ poor population sub-groups.

Structural electronic and mechanical properties of YM2 (M=Mn, Fe, Co) laves phase compounds: First principle calculations analyzed with datamining approach

Science.gov (United States)

Saidi, F.; Sebaa, N.; Mahmoudi, A.; Aourag, H.; Merad, G.; Dergal, M.

2018-06-01

We performed first-principle calculations to investigate structural, phase stability, electronic and mechanical properties for the Laves phases YM2 (M = Mn, Fe, Co) with C15, C14 and C36 structures. We used the density functional theory within the framework of both pseudo-potentials and plane wave basis using VASP (Vienna Ab Initio Software Package). The calculated equilibrium structural parameters are in accordance with available theoretical values. Mechanical properties were calculated, discussed, and analyzed with data mining approach in terms of structure stability. The results reveal that YCo2 is harder than YFe2 and YMn2.

Radon in the air in the Millenium of the Polish State Underground Tourist Route in Klodzko (Lower Silesia, PL)

International Nuclear Information System (INIS)

Przylibski, T.A.

1998-01-01

The paper presents results of measurements of average monthly radon concentrations in drifts of the Millenium of the Polish State Underground Tourist Route in Klodzko. The studies revealed no significant seasonal fluctuations of radon concentration. Constant influx of radon from the geological basement, and most of all from loess-like loams and rhyolite inliers, is compensated by a natural ventilation system. Only in the summer periods of elevated radon concentrations in the air of the drifts and chambers of the Route can occur. In individual sections it is possible to measure occasional higher radon concentrations caused by local air flow fluctuations in the drifts. The highest concentrations were measured in places with the poorest ventilation - blind drifts ventilated only by backward currents. The average radon concentrations measured do not exceed concentrations allowed in apartment buildings. Therefore, in the Route there is no risk of exposure to excessive amounts of radon for personnel and tourists. The results obtained in the Route's drifts may be compared with minimum results expected in basements of houses in the Old Town in Klodzko. The paper stresses also a role of natural ventilation in protection of underground constructions and apartment buildings against high radon concentrations in areas of its elevated emanations from the geological basement. (author)

Multipulse spectroscopy on the wild-type and YM210W Bacterial Reaction Centre uncovers a new intermediate state in the special pair excited state

Science.gov (United States)

Cohen Stuart, T. A.; van Grondelle, R.

2009-06-01

The Bacterial Reaction Centre (BRC) has a complex electronic excited state, P ∗, that evolves into subsequent charge separated product states P +H - and P +B -. Pump-dump-probe spectroscopy on the wild-type BRC and on YM210W, a mutant with a stabilized, long-lived P ∗ excited state, has uncovered a new charge-separated state in both BRC's. When P ∗ is dumped, a fraction of its population is transferred to this state that has a strong Stark shift in the accessory bacteriochlorophyll (B M) region which serves as a signature for P + and a lifetime highly comparable to the slow phase of P ∗ decay. This lead us propose this intermediate to be P +/P -.

Transfer of in vivo primed transgenic T cells supports allergic lung inflammation and FIZZ1 and Ym1 production in an IL-4Rα and STAT6 dependent manner

Directory of Open Access Journals (Sweden)

Keegan Achsah D

2011-10-01

Full Text Available Abstract Background CD4+ T helper type 2 (TH2 cells, their cytokines IL-4, IL-5 and IL-13 and the transcription factor STAT6 are known to regulate various features of asthma including lung inflammation, mucus production and airway hyperreactivity and also drive alternative activation of macrophages (AAM. However, the precise roles played by the IL-4/IL-13 receptors and STAT6 in inducing AAM protein expression and modulating specific features of airway inflammation are still unclear. Since TH2 differentiation and activation plays a pivotal role in this disease, we explored the possibility of developing an asthma model in mice using T cells that were differentiated in vivo. Results In this study, we monitored the activation and proliferation status of adoptively transferred allergen-specific naïve or in vivo primed CD4+ T cells. We found that both the naïve and in vivo primed T cells expressed similar levels of CD44 and IL-4. However, in vivo primed T cells underwent reduced proliferation in a lymphopenic environment when compared to naïve T cells. We then used these in vivo generated effector T cells in an asthma model. Although there was reduced inflammation in mice lacking IL-4Rα or STAT6, significant amounts of eosinophils were still present in the BAL and lung tissue. Moreover, specific AAM proteins YM1 and FIZZ1 were expressed by epithelial cells, while macrophages expressed only YM1 in RAG2-/- mice. We further show that FIZZ1 and YM1 protein expression in the lung was completely dependent on signaling through the IL-4Rα and STAT6. Consistent with the enhanced inflammation and AAM protein expression, there was a significant increase in collagen deposition and smooth muscle thickening in RAG2-/- mice compared to mice deficient in IL-4Rα or STAT6. Conclusions These results establish that transfer of in vivo primed CD4+ T cells can induce allergic lung inflammation. Furthermore, while IL-4/IL-13 signaling through IL-4Rα and STAT6 is

Improvement of the butanol production selectivity and butanol to acetone ratio (B:A) by addition of electron carriers in the batch culture of a new local isolate of Clostridium acetobutylicum YM1.

Science.gov (United States)

Nasser Al-Shorgani, Najeeb Kaid; Kalil, Mohd Sahaid; Wan Yusoff, Wan Mohtar; Shukor, Hafiza; Hamid, Aidil Abdul

2015-12-01

Improvement in the butanol production selectivity or enhanced butanol:acetone ratio (B:A) is desirable in acetone-butanol-ethanol (ABE) fermentation by Clostridium strains. In this study, artificial electron carriers were added to the fermentation medium of a new isolate of Clostridium acetobutylicum YM1 in order to improve the butanol yield and B:A ratio. The results revealed that medium supplementation with electron carriers changed the metabolism flux of electron and carbon in ABE fermentation by YM1. A decrease in acetone production, which subsequently improved the B:A ratio, was observed. Further improvement in the butanol production and B:A ratios were obtained when the fermentation medium was supplemented with butyric acid. The maximum butanol production (18.20 ± 1.38 g/L) was gained when a combination of methyl red and butyric acid was added. Although the addition of benzyl viologen (0.1 mM) and butyric acid resulted in high a B:A ratio of 16:1 (800% increment compared with the conventional 2:1 ratio), the addition of benzyl viologen to the culture after 4 h resulted in the production of 18.05 g/L butanol. Manipulating the metabolic flux to butanol through the addition of electron carriers could become an alternative strategy to achieve higher butanol productivity and improve the B:A ratio. Copyright © 2015 Elsevier Ltd. All rights reserved.

Zdrowie jamy ustnej u osób w podeszłym wieku zamieszkujących domy rodzinne i domy pomocy społecznej

Directory of Open Access Journals (Sweden)

Katarzyna Barczak

2016-12-01

Full Text Available Starzenie się populacji jest powodem powstawania wielu problemów ekonomicznych, socjologicznych, psychologicznych, politycznych i zdrowotnych. W ogólnym badaniu lekarskim, często problem zdrowia jamy ustnej jest pomijany lub traktowany bardzo pobieżnie. Ogólny stan zdrowia człowieka koreluje ze zdrowiem jego jamy ustnej. W przypadku choroby jednego układu, często dochodzi do pogorszenia funkcji innych narządów i w konsekwencji dochodzi do zaburzenia równowagi biologicznej całego organizmu. Zapobieganie próchnicy i chorobom przyzębia pozwala na utrzymanie własnego uzębienia i tym samym zapewnia prawidłową funkcję układu stomatognatycznego przez wiele lat. Celem pracy było określenie jak środowisko życia, warunki socjoekonomiczne i stan psychospołeczny wpływają na stan jamy ustnej ludzi starszych na podstawie dostępnego piśmiennictwa. Zachowania zdrowotne osób w wieku podeszłym są zróżnicowane i zależą od wielu czynników środowiskowych m.in. czy pacjenci są samodzielni, sprawni fizycznie i umysłowo, pozostają w warunkach swojego domu i rodziny, czy też przy braku zdolności do samodzielnego życia znajdują się w domach pomocy społecznej(DPS.Najczęściej to sytuacja materialna najbliższych i obowiązki życia codziennego najbliższej rodziny wpływają na decyzję o konieczności umieszczenia osoby starszej w DPS. Świadomość starszych pacjentów wzrasta, a ich potrzeby dotyczą nie tylko przywrócenia pełnej wydolności czynno- ściowej układu stomatognatycznego, lecz także estetycznego wyglądu i poczucia komfortu.

Cloning, expression and characterization of two S-ribosylhomocysteine lyases from Lactobacillus plantarum YM-4-3: Implication of conserved and divergent roles in quorum sensing.

Science.gov (United States)

Song, Xiao-Dong; Liu, Chen-Jian; Huang, Shi-Hao; Li, Xiao-Ran; Yang, En; Luo, Yi-Yong

2018-05-01

Quorum sensing (QS) is a means of cell-to-cell communication that regulates, via small signalling molecules, expression of a series of genes and controls multicellular behaviour in many bacterial species. The enzyme S-ribosylhomocysteine lyase (LuxS) transforms S-ribosylhomocysteine (SRH) into 4, 5-dihydroxy-2, 3-pentanedione (DPD), the precursor of the interspecies QS signalling molecule autoinducer-2 (AI-2). In this study, two LuxS-coding genes, luxS1 and luxS2, with 70% sequence identity were isolated from Lactobacillus plantarum YM-4-3, and overexpressed in Escherichia coli BL21 (DE3), and the protein products were purified successfully. After incubation of LuxS1 or LuxS2 with SRH, the reaction products were able to induce Vibrio harveyi BB170 bioluminescence, clearly demonstrating that both LuxS1 and LuxS2 synthesize AI-2 from SRH in vitro. Ellman's assay results revealed optimal temperatures for LuxS1 and LuxS2 of 45 and 37 °C, respectively, and their activities were stimulated or inhibited by several metal ions and chemical reagents. In addition, enzyme kinetics data showed that K m , V max and K cat value of LuxS1 for the substrate (SRH) were higher than that of LuxS2. These results suggest that LuxS1 and LuxS2 mediate QS in a temperature-dependent manner and may play conserved roles in AI-2 synthesis but exhibit different activities in response to external environmental stress. To our knowledge, this paper is the first report of two luxS genes present in one bacterial genome and the subsequent comparative elucidation of their functions in AI-2 production. Collectively, our study provides a solid basis for future research concerning the AI-2/LuxS QS system in L. plantarum YM-4-3. Copyright © 2018 Elsevier Inc. All rights reserved.

Aktywność fizyczna osób z przewlekłym wirusowym zapaleniem wątroby typu C

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Marta Estera Kowalska

2016-02-01

Independent Epidemiology Unit, Medical University of Lublin   Słowa kluczowe: wirusowe zapalenie wątroby typu C, aktywność fizyczna, edukacja zdrowotna. Key words: hepatitis C, physical activity, health education.     Streszczenie Wstęp Wirusowe zapalenie wątroby typu C stanowi jeden z głównych problemów zdrowia publicznego ze względu na długi okres bezobjawowy zakażenia wirusem HCV (hepatitis C virus oraz brak skutecznej szczepionki. Cel pracy Celem pracy była ocena poziomu aktywności fizycznej u osób z przewlekłym wirusowym zapaleniem wątroby typu C. Materiał i metody Materiałem wykorzystanym do badań były odpowiedzi na pytania zamknięte zawarte w autorskim kwestionariuszu ankiety. W badaniu wzięło udział 200 osób z potwierdzonym zakażeniem HCV. Wyniki Większość badanych podejmuje aktywność ruchową kilka razy w roku lub też sezonowo. Stwierdzono również, iż w badanej grupie im starszy wiek tym ankietowani rzadziej deklarują podejmowanie form aktywności fizycznej. Ponadto wykazano, iż aktywność fizyczna zmienia się wraz z poziomem wykształcenia. Im wyższy poziom wykształcenia, tym badani częściej podejmują aktywność fizyczną. Wnioski W grupie badanych pacjentów z wirusowym zapaleniem wątroby typu C występuje niska częstotliwość podejmowania aktywności fizycznej. Tylko młodzi ludzie oraz posiadający wyższe wykształcenie deklarują aktywność fizyczną prowadzoną kilka razy w roku.     Abstract Introduction and aim: Hepatitis C is one of the major public health problems due to the long period of asymptomatic infection with HCV and the lack of an effective vaccine. The aim of this study was to evaluate the level of physical activity in patients with chronic hepatitis C. Materials and methods: Material used for the study were responses to closed questions contained in the author's survey interview. The study involved 200 people with confirmed HCV infection. Results: Most of the respondents take

Escitalopram w leczeniu zaburzeń psychicznych chorych w podeszłym wieku

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Tomasz Sobów

2015-07-01

Full Text Available Farmakoterapia zaburzeń psychicznych u chorych w podeszłym wieku jest często trudna i ograniczona powszechniejszym niż u młodszych chorych występowaniem objawów niepożądanych, interakcji lekowych oraz koniecznością brania pod uwagę współchorobowości, nie tylko psychiatrycznej, ale przede wszystkim – somatycznej. Te aspekty, razem z wieloczynnikową patogenezą zaburzeń i znaczną w wielu badaniach odpowiedzią placebo, prowadzą do względnie niższych wskaźników efektywności klinicznej leczenia. Właściwy wybór leku, uwzględniający jego skuteczność i bezpieczeństwo, jest zatem kluczowy dla sukcesu terapii. Escitalopram to obiecujący lek dla starszych chorych. Jego znaczna selektywność farmakodynamiczna, korzystny profil farmakokinetyczny, w tym stosunkowo niewielki potencjał wchodzenia w interakcje lekowe, oraz dość rzadkie wywoływanie poważnych objawów ubocznych spowodowały – wraz z zadowalającymi wynikami badań klinicznych – częste i z korzyścią dla pacjentów stosowanie escitalopramu w zaburzeniach nastroju (także w tzw. organicznych i zaburzeniach lękowych, a ostatnio jako leku korygującego zaburzenia zachowania towarzyszące otępieniu, takie jak pobudzenie, agresja czy psychoza. Dodatkowym ważnym aspektem stosowania escitalopramu jest łatwość podawania (jedna dawka na dobę oraz dostępność postaci w kroplach, która może być szczególnie użyteczna dla chorych z problemami w połykaniu, przyjmujących wiele leków, karmionych poprzez gastrostomię czy z zaburzeniami funkcji poznawczych.

Problems of world energy supply until the turn of the millenium

International Nuclear Information System (INIS)

Dolinski, U.

1981-01-01

After a historical review of energy supply, world energy consumption until the year 2000 is estimated along with the potential of oil, natural gas, coal, nuclear power, and renewable energy sources. (UA) [de

Wpływ aktywności fizycznej na sprawność funkcji poznawczych osób w podeszłym wieku i na przebieg choroby Alzheimera

Directory of Open Access Journals (Sweden)

Tomasz Gabryelewicz

2013-04-01

Full Text Available W miarę starzenia się społeczeństwa coraz więcej osób doświadcza związanego z wiekiem osłabienia pamięci i zaburzeń innych funkcji poznawczych. Dla części tych osób zaburzenia te mogą być zwiastunem otępienia. Wiadomo, że jego najczęstszą przyczyną jest choroba Alzheimera (Alzheimer’s disease, AD. Stosowane obecnie metody farmakologicznego zapobiegania i leczenia AD są mało skuteczne. Powoduje to, że podejmowane są próby terapii mających na celu spowolnienie przebiegu AD i opóźnienie początku objawowej fazy klinicznej choroby. Może to znacząco wpływać na zmniejszenie zapadalności na AD. Wyniki biologicznych, epidemiologicznych i randomizowanych badań kontrolowanych wskazują na korzystny wpływ regularnej aktywności fizycznej na zapobieganie występowaniu zaburzeń poznawczych u osób w podeszłym wieku i spowolnienie przebiegu AD. Okazuje się, że aktywność fizyczna, szczególnie w połączeniu z aktywnością umysłową i intensywną aktywnością społeczną, może być użyteczną, a przy tym tańszą i bezpieczniejszą metodą zapobiegania AD niż profilaktyka farmakologiczna. Dalszych badań wymaga określenie precyzyjnych zaleceń dotyczących rodzaju, czasu trwania i intensywności tych form terapii. Istnieje jednak szansa, że w bliskiej przyszłości będziemy mogli stosować potwierdzone zasady zapobiegania AD dotyczące zachowań dietetycznych, aktywności społecznej, umysłowej i fizycznej. Wymienione wyżej rodzaje interwencji niefarmakologicznych wpływają również pozytywnie na codzienne funkcjonowanie i ogólną jakość życia osób w podeszłym wieku i pacjentów z AD.

Online Appendix to Y2K

OpenAIRE

Stephanie Schmitt-Grohe; Martin Uribe

1998-01-01

As the millenium draws to an end, the threat posed by the Year 2000 (Y2K) problem is inducing vast private and public spending on its remediation. In this paper, we embed the Y2K problem into a dynamic general equilibrium framework. We model the Y2K problem as an anticipated, permanent loss to output whose magnitude can be lessened by investing resources in advance. Our model replicates three observed characteristics of the dynamics triggered by the Y2K bug: (1) Precautionary investment: inve...

Vitamin D: A millenium perspective.

Science.gov (United States)

Holick, Michael F

2003-02-01

Vitamin D is one of the oldest hormones that have been made in the earliest life forms for over 750 million years. Phytoplankton, zooplankton, and most plants and animals that are exposed to sunlight have the capacity to make vitamin D. Vitamin D is critically important for the development, growth, and maintenance of a healthy skeleton from birth until death. The major function of vitamin D is to maintain calcium homeostasis. It accomplishes this by increasing the efficiency of the intestine to absorb dietary calcium. When there is inadequate calcium in the diet to satisfy the body's calcium requirement, vitamin D communicates to the osteoblasts that signal osteoclast precursors to mature and dissolve the calcium stored in the bone. Vitamin D is metabolized in the liver and then in the kidney to 1,25-dihydroxyvitamin D [1,25(OH)(2)D]. 1,25(OH)(2)D receptors (VDR) are present not only in the intestine and bone, but in a wide variety of other tissues, including the brain, heart, stomach, pancreas, activated T and B lymphocytes, skin, gonads, etc. 1,25(OH)(2)D is one of the most potent substances to inhibit proliferation of both normal and hyperproliferative cells and induce them to mature. It is also recognized that a wide variety of tissues, including colon, prostate, breast, and skin have the enzymatic machinery to produce 1,25(OH)(2)D. 1,25(OH)(2)D and its analogs have been developed for treating the hyperproliferative disease psoriasis. Vitamin D deficiency is a major unrecognized health problem. Not only does it cause rickets in children, osteomalacia and osteoporosis in adults, but may have long lasting effects. Chronic vitamin D deficiency may have serious adverse consequences, including increased risk of hypertension, multiple sclerosis, cancers of the colon, prostate, breast, and ovary, and type 1 diabetes. There needs to be a better appreciation of the importance of vitamin D for overall health and well being. Copyright 2002 Wiley-Liss, Inc.

Childhood obesity: the epidemic of the third millenium.

Science.gov (United States)

Archenti, Anna; Pasqualinotto, Lucia

2008-08-01

Italy is the European country with the most obese and overweight children and teenagers. Most of them have a family history of obesity and this condition may increase the risk of many diseases. This study involved 52 patients (32 females and 20 males) between 6 and 17 years of age with an average BMI of31.5. The patients underwent a three-month treatment which included an overview of individual caloric intake and creation of a suitable diet, an exercise program and counselling sessions with a psychologist in order to support the patients and families. Anthropometric changes were evaluated at the end of the three months and during follow-up to assess the effectiveness of the treatment. Before starting the treatment the average weight of the patients was 81.8 kg, after the treatment it decreased to 79.4 kg. Likewise, the average BMI of the patients was 31.3 before the treatment and 30.4 after the treatment. Both of these results are statistically significant. This study confirms the importance of teamwork in the treatment of childhood obesity and the importance of approaching the problem with the entire family. A real problem exists for patients who are strongly dependent on the habits, determination and flexibility of their family. In conclusion, the success of this treatment is strongly related to the psychological attitude of the family.

Perturbations of the Yang-Mills field in the universe

International Nuclear Information System (INIS)

Zhao Wen

2009-01-01

It has been suggested that the Yang-Mills (YM) field can be a kind of candidate for the inflationary field at high energy scales or dark energy at very low energy scales, which can naturally give the equation of state -1 -2 , from which it follows that the equation of state of the YM field always goes to -1, independent of the initial conditions. By solving the first order Einstein equations and the YM field equations, we find that in the YM field inflationary models, the scale-invariant primordial perturbation power spectrum cannot be generated. Therefore, only using this kind of YM field is not enough to account for inflationary sources. However, as a kind of candidate for dark energy, the YM field has the 'sound speed' cs 2 S = -1/3 < 0, which makes the perturbation oe have a damping behavior at large scales. This provides a way to distinguish the YM field dark energy models from other kinds of models. (research papers)

Nutrient recovery from the dry grind process using sequential micro and ultrafiltration of thin stillage.

Science.gov (United States)

Arora, Amit; Dien, Bruce S; Belyea, Ronald L; Singh, Vijay; Tumbleson, M E; Rausch, Kent D

2010-06-01

The effectiveness of microfiltration (MF) and ultrafiltration (UF) for nutrient recovery from a thin stillage stream was determined. When a stainless steel MF membrane (0.1microm pore size) was used, the content of solids increased from 7.0% to 22.8% with a mean permeate flux rate of 45L/m(2)/h (LMH), fat increased and ash content decreased. UF experiments were conducted in batch mode under constant temperature and flow rate conditions. Permeate flux profiles were evaluated for regenerated cellulose membranes (YM1, YM10 and YM100) with molecular weight cut offs of 1, 10 and 100kDa. UF increased total solids, protein and fat and decreased ash in retentate stream. When permeate streams from MF were subjected to UF, retentate total solids concentrations similar to those of commercial syrup (23-28.8%) were obtained. YM100 had the highest percent permeate flux decline (70% of initial flux) followed by YM10 and YM1 membranes. Sequential filtration improved permeate flux rates of the YM100 membrane (32.6-73.4LMH) but the percent decline was also highest in a sequential MF+YM100 system. Protein recovery was the highest in YM1 retentate. Removal of solids, protein and fat from thin stillage may generate a permeate stream that may improve water removal efficiency and increase water recycling. Copyright 2010 Elsevier Ltd. All rights reserved.

The effect of Ga-mee-gwui-ryong-tang and Yuk-mee ji-hwang-tang Herbal-acupuncture on the growth of mice

Directory of Open Access Journals (Sweden)

Min-jung Kim

2006-12-01

Full Text Available Objectives : To investigate the effect of Ga-mee-Gwui-ryong-tang herbal acupuncture (GR-HA at GB39 and ST36 and the effect of Yuk-mee ji-hwang-tang herbal acupuncture (YM-HA at GB39 and KI10 on growth in mice. Methods : Mice were divided into 7 groups(n=10 ; saline-ST36, saline-GB39, saline-KI10, GR-HA-ST36 group treated with GR-HA at right ST36, GR-HA-GB39 group treated with GR-HA at right GB39, YM-HA-GB39 group treated with YM-HA at right GB39, YM-HA-KI10 group treated with YM-HA at right KI10. Saline-ST36 group, saline-GB39 group and saline-KI10 group were injected with saline at right ST36, GB39, KI10 respectively. Saline injection and HA were performed 3 times a week for 18 days. The length(total height, body length and tail length, weight and the protein efficiency ratio were measured as well as IGF-1 level in serum. Results : 1. GR-HA at GB39 and GR-HA at ST36 promoted growth in weight, tail length and total height but there was no statistical significance. 2. GR-HA at GB39 significantly promoted protein efficiency on the 14th day and GR-HA at ST36 on the 3rd day. 3. GR-HA at GB39 significantly increased serum IGF-1. GR-HA at ST36 increased IGF-1 slightly but with no statistical significance. 4. YM-HA at GB39 and YM-HA at KI10 promoted growth in weight, height, tail length and total height but there was no statistical relevance. 5. YM-HA at GB39 and YM-HA at KI10 significantly promoted protein efficiency on the 14th day. 6. YM-HA at GB39 and YM-HA at KI10 significantly increased serum IGF-1. Serum IGF-1 level of YM-HA-KI10 group was significantly higher than that of YM-HA-GB39 group. 7. Serum IGF-1 level of GR-HA-GB39 group was significantly higher than that of YM-HA-GB39 group. Conclusions : GR-HA and YM-HA both may promote growth. This study suggests that herbal acupuncture at GB39 is more effective with Gwui-ryong-tang than Yuk-mee ji-hwang-tang to promote growth. It also suggests that Yuk-mee ji-hwang-tang herbal acupuncture is more

Seven new species of Begonia (Begoniaceae) in Northern Vietnam and Southern China

Science.gov (United States)

Chen, Wen-Hong; Radbouchoom, Sirilak; Nguyen, Hieu Quang; Nguyen, Hiep Tien; Nguyen4, Khang Sinh; Shui, Yu-Min

2018-01-01

Abstract Since 2016, KIB (Kunming Institute of Botany) and CPC (Centre for Plant Conservation of Vietnam) have conducted several surveys in the transboundary karst regions in Northern Vietnam and Southern China and seven new species in the genus Begonia Linn. (Begoniaceae) are firstly described. Amongst them, two species, Begonia albopunctata Y.M. Shui, W.H. Chen & H.Q. Nguyen and B. erectocarpa H.Q. Nguyen, Y.M. Shui & W.H. Chen, respectively belong to section Sphenanthera with berry fruits and section Leprosae with clavate berry fruits; four species, B. gulongshanensis Y.M. Shui & W. H. Chen, B. minissima H.Q. Nguyen, Y.M. Shui & W.H. Chen, B. mollissima Y.M. Shui, H.Q. Nguyen & W.H. Chen, B. rhytidophylla Y.M. Shui & W.H. Chen, belong to section Coelocentrum with parietal placentation; one species, Begonia bambusetorum H.Q. Nguyen, Y.M. Shui & W.H. Chen, belongs to section Diploclinium with 3-loculed ovary and capsules. The diagnostic characters of these species are described and illustrated in the text and photographs. PMID:29416422

Interactions of Rosiglitazone and Anti.Arrhythmic Drugs in Animal ...

African Journals Online (AJOL)

Interactions of Rosiglitazone and Anti.Arrhythmic Drugs in Animal Model. YM Mohammed, EI Mohammed, N Mohiuddin, SS Syeda. Abstract. Background: Diabetes increases the risk of vascular problems by two times compared with a healthy individual, with deposition of fats in blood vessel and this includes cardiovascular ...

Yerba Mat? (Ilex paraguariensis) Metabolic, Satiety, and Mood State Effects at Rest and during Prolonged Exercise

OpenAIRE

Alkhatib, Ahmad; Atcheson, Roisin

2017-01-01

Yerba Mat? (YM), has become a popular herb ingested for enhancing metabolic health and weight-loss outcomes. No studies have tested the combined metabolic, satiety, and psychomotor effects of YM during exercise. We tested whether YM ingestion affects fatty acid oxidation (FAO), profile of mood state score (POMS), and subjective appetite scale (VAS), during prolonged moderate exercise. Twelve healthy active females were randomized to ingest either 2 g of YM or placebo (PLC) in a repeated-measu...

Standard deviation of carotid young's modulus and presence or absence of plaque improves prediction of coronary heart disease risk.

Science.gov (United States)

Niu, Lili; Zhang, Yanling; Qian, Ming; Xiao, Yang; Meng, Long; Zheng, Rongqin; Zheng, Hairong

2017-11-01

The stiffness of large arteries and the presence or absence of plaque are associated with coronary heart disease (CHD). Because arterial walls are biologically heterogeneous, the standard deviation of Young's modulus (YM-std) of the large arteries may better predict coronary atherosclerosis. However, the role of YM-std in the occurrence of coronary events has not been addressed so far. Therefore, this study investigated whether the carotid YM-std and the presence or absence of plaque improved CHD risk prediction. One hundred and three patients with CHD (age 66 ± 11 years) and 107 patients at high risk of atherosclerosis (age 61 ± 7 years) were recruited. Carotid YM was measured by the vessel texture matching method, and YM-std was calculated. Carotid intima-media thickness was measured by the MyLab 90 ultrasound Platform employed dedicated software RF-tracking technology. In logistic regression analysis, YM-std (OR = 1·010; 95% CI = 1·003-1·016), carotid plaque (OR = 16·759; 95% CI = 3·719-75·533) and YM-std plus plaque (OR = 0·989; 95% CI = 0·981-0·997) were independent predictors of CHD. The traditional risk factors (TRF) plus YM-std plus plaque model showed a significant improvement in area under the receiver-operating characteristic curve (AUC), which increased from 0·717 (TRF only) to 0·777 (95% CI for the difference in adjusted AUC: 0·010-0·110). Carotid YM-std is a powerful independent predictor of CHD. Adding plaque and YM-std to TRF improves CHD risk prediction. © 2016 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

Correlation of polyunsaturated fatty acids with the cold adaptation of Rhodotorula glutinis.

Science.gov (United States)

He, Jing; Yang, Zhaojie; Hu, Binbin; Ji, Xiuling; Wei, Yunlin; Lin, Lianbing; Zhang, Qi

2015-11-01

This study aimed to investigate the correlation between the cold adaptation of Rhodotorula glutinis YM25079 and the membrane fluidity, content of polyunsaturated fatty acids and mRNA expression level of the Δ(12)-desaturase gene. The optimum temperature for YM25079 growth was analysed first, then the composition changes of membrane lipid in YM25079 were detected by GC-MS and membrane fluidity was evaluated by 1-anilinonaphthalene-8-sulphonate (ANS) fluorescence. Meanwhile, the encoding sequence of Δ(12)-fatty acid desaturase in YM25079 was cloned and further transformed into Saccharomyces cerevisiae INVScl for functional analysis. The mRNA expression levels of Δ(12)-fatty acid desaturase at 15°C and 25°C were analysed by real-time PCR. YM25079 could grow at 5-30°C, with the optimum temperature of 15°C. The membrane fluidity of YM25079 was not significantly reduced when the culture temperature decreased from 25°C to 15°C, but the content of polyunsaturated fatty acids (PUFAs), including linoleic acid and α-Linolenic acid increased significantly from 29.4% to 55.39%. Furthermore, a novel Δ(12)-fatty acid desaturase gene YM25079RGD12 from YM25079 was successfully identified and characterized, and the mRNA transcription level of the Δ(12)-desaturase gene was about five-fold higher in YM25079 cells grown at 15°C than that at 25°C. These results suggests that the cold adaptation of Rhodotorula glutinis YM25079 might result from higher expression of genes, especially the Δ(12)-fatty acid desaturase gene, during polyunsaturated fatty acids biosynthesis, which increased the content of PUFAs in the cell membrane and maintained the membrane fluidity at low temperature. Copyright © 2015 John Wiley & Sons, Ltd.

Cell Culturing of Cytoskeleton

Science.gov (United States)

2004-01-01

Biomedical research offers hope for a variety of medical problems, from diabetes to the replacement of damaged bone and tissues. Bioreactors, which are used to grow cells and tissue cultures, play a major role in such research and production efforts. Cell culturing, such as this bone cell culture, is an important part of biomedical research. The BioDyn payload includes a tissue engineering investigation. The commercial affiliate, Millenium Biologix, Inc., has been conducting bone implant experiments to better understand how synthetic bone can be used to treat bone-related illnesses and bone damaged in accidents. On STS-95, the BioDyn payload will include a bone cell culture aimed to help develop this commercial synthetic bone product. Millenium Biologix, Inc., is exploring the potential for making human bone implantable materials by seeding its proprietary artificial scaffold material with human bone cells. The product of this tissue engineering experiment using the Bioprocessing Modules (BPMs) on STS-95 is space-grown bone implants, which could have potential for dental implants, long bone grafts, and coating for orthopedic implants such as hip replacements.

Implication of chemo-resistant memory T cells for immune surveillance in patients with sarcoma receiving chemotherapy.

Science.gov (United States)

Shibayama, Yuji; Tsukahara, Tomohide; Emori, Makoto; Murata, Kenji; Mizushima, Emi; Hirohashi, Yoshihiko; Kanaseki, Takayuki; Nakatsugawa, Munehide; Kubo, Terufumi; Yamashita, Toshihiko; Sato, Noriyuki; Torigoe, Toshihiko

2017-09-01

Chemotherapy has improved the prognosis of patients with sarcomas. However, it may suppress anti-tumor immunity. Recently, we reported a novel CD8 + memory T cell population with a chemo-resistance property, "young memory" T (T YM ) cells. In this study, we investigated the proportion and function of T YM cells in peripheral blood of healthy donors and sarcoma patients who received chemotherapy and those who did not. The proportion of T YM cells was significantly decreased in patients compared with that in healthy donors. In healthy donors, anti-EBV CTLs were induced using mixed lymphocyte peptide culture, from not only T YM cells but also T CM and T EM cells. No CTLs directed to tumor-associated antigens were induced. In sarcoma patients who did not receive chemotherapy, in addition to anti-EBV CTLs, CTLs directed to the tumor-associated antigen PBF were induced from T YM , T CM and T EM cells. In sarcoma patients who received chemotherapy, EBV-specific CTLs were induced from T YM cells but were hardly induced from T EM cells. Interestingly, CTLs directed to the anti-tumor-associated antigen PBF were induced from T YM cells but not from the T CM and T EM cells in sarcoma patients who received chemotherapy. The findings suggest that T YM cells are resistant to chemotherapy and can firstly recover from the nadir. T YM cells might be important for immunological memory, especially in sarcoma patients receiving chemotherapy. © 2017 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

Ioligtiogsarmoede: 'n Christelik etiese refleksie

Directory of Open Access Journals (Sweden)

J.J. Britz

2001-08-01

Full Text Available Information poverty does not only pertain to the lack of essential information, but can also be defined as a condition of life where the majority of people within a specific context do not have the means nor the skills to access essential information for survival and development. It is a form of poverty that is furthermore characterised by global social injustice, and can as such be seen as one of the major poverty problems facing the new millenium. This article investigates the problem of information poverty from a moral perspective, and suggests ethical guidelines to address this form of poverty.

Identifiation of Phymatolithon lamii (Me. Lemoine Y.M. Chamberlain 1991 following bleaching in the upper intertidal zone of the Minas Basin, Nova Scotia, Canada

Directory of Open Access Journals (Sweden)

Brady Keith Quinn

2016-03-01

Full Text Available Objective: To identify an unusual encrusting calcareous organism found growing on upper intertidal rocks along the coast of the Minas Basin, Nova Scotia, Canada, which was thought to potentially represent a new, perhaps invasive species to the area. Methods: Observations were made of the organism growing in situ and of intact and dissected specimens under microscopes in the laboratory. Taxonomic keys were used to determine probable identity of the organism as a tunicate, sponge, bryozoan, marine lichen, or coralline red alga. These keys were then further used to identify samples to species. Results: The organism was determined to be Phymatolithon lamii (Me. Lemoine Y.M. Chamberlain 1991, an encrusting coralline red alga native to the study region. This species normally occurs in the subtidal zone, so its occurrence in the high intertidal zone was unusual and resulted in the alga becoming bleached and taking on an unusual appearance. Conclusions: The sample did not represent a new or invasive species to the study area. However, occurrence of this species on the high intertidal zone was novel and may have resulted from unusual climatic and/or oceanographic conditions in the study area in 2015 that allowed this alga to settle and grow in the intertidal zone for a time before death and bleaching occurred. Events such as this resulting from climate change may negatively impact recruitment to populations of coastal marine species and should be investigated further.

BRST quantization of 2d-Yang Mills theory with anomalies

International Nuclear Information System (INIS)

Kalau, Wolfgang

1992-01-01

The BRST-quantization of anomalous 2d-Yang Mills (YM) theory is discussed. Since an oscillator basis for the YM-Fock-space is used the anomaly appears already for a pure YM-system and the constraints form a Kac-Moody algebra with negative central charge. The coupling of chiral fermions is also discussed and it is found that the BRST-cohomology for systems with chiral fermions in a sufficiently large representation of the gauge group is completely equivalent to the cohomology of the finite dimensional gauge group. For pure YM theory or YM theory coupled to chiral fermions in small representations there exists an infinite number of inequivalent cohomology classes. This is discussed in some detail for the example of SU(2). (author). 15 refs

Corrosion of candidate container materials by Yucca Mountain bacteria

International Nuclear Information System (INIS)

Horn, J; Jones, D; Lian, T; Martin, S; Rivera, A

1999-01-01

Several candidate container materials have been studied in modified Yucca Mountain (YM) ground water in the presence or absence of YM bacteria. YM bacteria increased corrosion rates by 5-6 fold in UNS G10200 carbon steel, and nearly 100-fold in UNS NO4400 Ni-Cu alloy. YM bacteria caused microbiologically influenced corrosion (MIC) through de-alloying or Ni-depletion of Ni-Cu alloy as evidenced by scanning electronic microscopy (SEM) and inductively coupled plasma spectroscopy (ICP) analysis. MIC rates of more corrosion-resistant alloys such as UNS NO6022 Ni-Cr- MO-W alloy, UN's NO6625 Ni-Cr-Mo alloy, and UNS S30400 stainless steel were measured below 0.05 umyr, however YM bacteria affected depletion of Cr and Fe relative to Ni in these materials. The chemical change on the metal surface caused by depletion was characterized in anodic polarization behavior. The anodic polarization behavior of depleted Ni-based alloys was similar to that of pure Ni. Key words: MIC, container materials, YM bacteria, de-alloying, Ni-depletion, Cr-depletion, polarization resistance, anodic polarization,

[Faba bean fusarium wilt (Fusarium oxysporum )control and its mechanism in different wheat varieties and faba bean intercropping system].

Science.gov (United States)

Dong, Yan; Dong, Kun; Zheng, Yi; Tang, Li; Yang, Zhi-Xian

2014-07-01

Field experiment and hydroponic culture were conducted to investigate effects of three wheat varieties (Yunmai 42, Yunmai 47 and Mianyang 29) and faba bean intercropping on the shoot biomass, disease index of fusarium wilt, functional diversity of microbial community and the amount of Fusarium oxysporum in rhizosphere of faba bean. Contents and components of the soluble sugars, free amino acids and organic acids in the root exudates were also examined. Results showed that, compared with monocropped faba bean, shoot biomass of faba bean significantly increased by 16.6% and 13.4%, disease index of faba bean fusarium wilt significantly decreased by 47.6% and 23.3% as intercropped with Yunmai 42 and Yunmai 47, but no significant differences of both shoot biomass and disease index were found as intercropped with Mianyang 29. Compared with monocropped faba bean, the average well color development (AWCD value) and total utilization ability of carbon sources of faba bean significantly increased, the amount of Fusarium oxysporum of faba bean rhizosphere significantly decreased, and the microbial community structures of faba bean rhizosphere changed as intercropped with YM42 and YM47, while no significant effects as intercropped with MY29. Total contents of soluble sugar, free amino acids and organic acids in root exudates were in the trend of MY29>YM47>YM42. Contents of serine, glutamic, glycine, valine, methionine, phenylalanine, lysine in root exudates of MY29 were significantly higher than that in YM42 and YM47. The arginine was detected only in the root exudates of YM42 and YM47, and leucine was detected only in the root exudates of MY29. Six organic acids of tartaric acid, malic acid, citric acid, succinic acid, fumaric acid, t-aconitic acid were detected in root exudates of MY29 and YM47, and four organic acids of tartaric acid, malic acid, citric acid, fumaric acid were detected in root exudates of YM42. Malic acid content in root exudates of YM47 and MY29 was

Performance assessment calculational exercises

International Nuclear Information System (INIS)

Barnard, R.W.; Dockery, H.A.

1990-01-01

The Performance Assessment Calculational Exercises (PACE) are an ongoing effort coordinated by Yucca Mountain Project Office. The objectives of fiscal year 1990 work, termed PACE-90, as outlined in the Department of Energy Performance Assessment (PA) Implementation Plan were to develop PA capabilities among Yucca Mountain Project (YMP) participants by calculating performance of a Yucca Mountain (YM) repository under ''expected'' and also ''disturbed'' conditions, to identify critical elements and processes necessary to assess the performance of YM, and to perform sensitivity studies on key parameters. It was expected that the PACE problems would aid in development of conceptual models and eventual evaluation of site data. The PACE-90 participants calculated transport of a selected set of radionuclides through a portion of Yucca Mountain for a period of 100,000 years. Results include analyses of fluid-flow profiles, development of a source term for radionuclide release, and simulations of contaminant transport in the fluid-flow field. Later work included development of a problem definition for perturbations to the originally modeled conditions and for some parametric sensitivity studies. 3 refs

Formation of fission-fragment mass distribution for nuclei lighter than thorium

International Nuclear Information System (INIS)

Itkis, M.G.; Mul'gin, S.I.; Rusanov, A.Y.; Okolovich, A.N.; Smirenkin, G.N.

1986-01-01

A phenomenological approach to description of fission-fragment mass distribution Y(M) for nuclei in the vicinity of Pb is developed and used to extract from the experimental Y(M) data the nuclear deformation potential energy V(M) and its components: the macroscopic (liquid-drop) part and the shell correction in the transition state. The results of the analysis are compared with the theoretically obtained V(M) and Y(M). The three-hump fragment-mass distributions observed in Ra fission are satisfactorily described within the framework of the approach developed. The properties of the symmetric and asymmetric fission valleys and the related Y(M) components are discussed

String tensions in deformed Yang-Mills theory

Science.gov (United States)

Poppitz, Erich; Shalchian T., M. Erfan

2018-01-01

We study k-strings in deformed Yang-Mills (dYM) with SU(N) gauge group in the semiclassically calculable regime on R^3× S^1 . Their tensions Tk are computed in two ways: numerically, for 2 ≤ N ≤ 10, and via an analytic approach using a re-summed perturbative expansion. The latter serves both as a consistency check on the numerical results and as a tool to analytically study the large-N limit. We find that dYM k-string ratios Tk/T1 do not obey the well-known sine- or Casimir-scaling laws. Instead, we show that the ratios Tk/T1 are bound above by a square root of Casimir scaling, previously found to hold for stringlike solutions of the MIT Bag Model. The reason behind this similarity is that dYM dynamically realizes, in a theoretically controlled setting, the main model assumptions of the Bag Model. We also compare confining strings in dYM and in other four-dimensional theories with abelian confinement, notably Seiberg-Witten theory, and show that the unbroken Z_N center symmetry in dYM leads to different properties of k-strings in the two theories; for example, a "baryon vertex" exists in dYM but not in softly-broken Seiberg-Witten theory. Our results also indicate that, at large values of N, k-strings in dYM do not become free.

Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance.

Directory of Open Access Journals (Sweden)

John Koren

Full Text Available MKT-077, a rhodacyanine dye, was shown to produce cancer specific cell death. However, complications prevented the use of this compound beyond clinical trials. Here we describe YM-1, a derivative of MKT-077. We found that YM-1 was more cytotoxic and localized differently than MKT-077. YM-1 demonstrated this cytotoxicity across multiple cancer cell lines. This toxicity was limited to cancer cell lines; immortalized cell models were unaffected. Brief applications of YM-1 were found to be non-toxic. Brief treatment with YM-1 restored tamoxifen sensitivity to a refractory tamoxifen-resistant MCF7 cell model. This effect is potentially due to altered estrogen receptor alpha phosphorylation, an outcome precipitated by selective reductions in Akt levels (Akt/PKB. Thus, modifications to the rhodocyanine scaffold could potentially be made to improve efficacy and pharmacokinetic properties. Moreover, the impact on tamoxifen sensitivity could be a new utility for this compound family.

Yerba Maté (Ilex paraguariensis) Metabolic, Satiety, and Mood State Effects at Rest and during Prolonged Exercise.

Science.gov (United States)

Alkhatib, Ahmad; Atcheson, Roisin

2017-08-15

Yerba Maté (YM), has become a popular herb ingested for enhancing metabolic health and weight-loss outcomes. No studies have tested the combined metabolic, satiety, and psychomotor effects of YM during exercise. We tested whether YM ingestion affects fatty acid oxidation (FAO), profile of mood state score (POMS), and subjective appetite scale (VAS), during prolonged moderate exercise. Twelve healthy active females were randomized to ingest either 2 g of YM or placebo (PLC) in a repeated-measures design. Participants rested for 120 min before performing a 30-min cycling exercise corresponding to individuals' crossover point intensity (COP). FAO, determined using indirect calorimetry, was significantly higher during the 30-min exercise in YM vs. PLC (0.21 ± 0.07 vs. 0.17 ± 0.06 g/min, p exercise at targeted "fat-loss"' intensities augments FAO and improves measures of satiety and mood state. Such positive combined metabolic, satiety, and psychomotor effects may provide an important role for designing future fat and weight-loss lifestyle interventions.

Thermoelectrical properties of the compounds ScM{sup VIII}Sb and YM{sup VIII}Sb (M{sup VIII} = Ni, Pd, Pt)

Energy Technology Data Exchange (ETDEWEB)

Oestreich, J; Probst, U; Richardt, F; Bucher, E [University of Konstanz, PO Box X916, D-78457 Konstanz (Germany)

2003-02-05

The research into new materials with good thermoelectric properties has revealed new compounds consisting of metallic elements (Bando Y, Suemitsu T, Takagi K, Tokushima H, Echizen Y, Katoh K, Umeo K, Maeda Y and Takabatake T 2000 J. Alloys Compounds 313 1-6, Ghelani N, Loo S, Chung D, Sportouch S, Nardi S, Kanatzidis M, Hogan T and Nolas G 2000 Mater. Res. Soc. 626 Z8.6.1). The half-Heusler compound ZrNiSn, in particular, shows promising thermoelectric properties and has been studied by many scientists during recent years (Uher C, Hu S, Yang J, Meisner G P and Morelli D T 1997 Proc. ICT'97: 16th Int. Conf. on Thermoelectrics pp 485-8, Romaka L P, Stadnyk Yu V, Goryn A M, Gorelenko Yu K and Skolozdra R V 1997 Proc. ICT'97: 16th Int. Conf. on Thermoelectrics pp 516-19, Hohl H, Ramirez A P, Goldmann C, Ernst G, Woelfing B and Bucher E 1998 J. Phys.: Condens. Matter 11 1697-709, Oestreich J, Kaefer W, Richardt F, Probst U and Bucher E 1999 Proc. 5th European Workshop on Thermoelectrics pp 192-5). In an effort to find new thermoelectric materials, the half-Heusler compounds of the groups ScM{sup VIII}Sb and YM{sup VIII}Sb (M{sup VIII} = Ni, Pd, Pt) were synthesized by arc melting and the thermoelectric properties were examined by standard characterization methods. Doping experiments showed that it is possible to change the electrical properties of the compounds while retaining the half-Heusler structure. Within the two groups, YPtSb showed the best thermoelectrical properties. At a temperature of 400 K the electrical conductivity of YPtSb is 748{omega}{sup -1} cm{sup -1} and the Seebeck coefficient is 116.3{mu}V K{sup -1}. The thermal conductivity at 400 K extrapolated using the Wiedemann-Franz law is 2.87 W K{sup -1} m{sup -1}. This leads to a dimensionless figure of merit of 0.14.

Absence of U(1) anomalous superamplitudes in N≥5 supergravities

Energy Technology Data Exchange (ETDEWEB)

Freedman, Daniel Z. [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University,Stanford, CA 94305 (United States); Center for Theoretical Physics and Department of Mathematics,Massachusetts Institute of Technology,Cambridge, MA 02139 (United States); Kallosh, Renata; Murli, Divyanshu [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University,Stanford, CA 94305 (United States); Proeyen, Antoine Van [KU Leuven, Institute for Theoretical Physics,Celestijnenlaan 200D, B-3001, Leuven (Belgium); Yamada, Yusuke [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University,Stanford, CA 94305 (United States)

2017-05-12

We list all potential candidates for U(1) anomalous non-local 1-loop 4-point amplitudes and higher loop UV divergences in N≥5 supergravities. The relevant chiral superinvariants are constructed from linearized chiral superfields and define the corresponding superamplitudes. The anomalous amplitudes, of the kind present in N=4, are shown to be absent in N≥5. In N=6 supergravity the result is deduced from the double-copy (N=4){sub YM}×(N=2){sub YM} model, whereas in N=5,8 the result on absence of anomalous amplitudes is derived in supergravities as well as in the (N=4){sub YM}×(N−4){sub YM} double-copy models.

Uncertainty and sensitivity analysis in the 2008 performance assessment for the proposed repository for high-level radioactive waste at Yucca Mountain, Nevada

International Nuclear Information System (INIS)

Helton, Jon Craig; Sallaberry, Cedric M.; Hansen, Clifford W.

2010-01-01

Extensive work has been carried out by the U.S. Department of Energy (DOE) in the development of a proposed geologic repository at Yucca Mountain (YM), Nevada, for the disposal of high-level radioactive waste. As part of this development, an extensive performance assessment (PA) for the YM repository was completed in 2008 (1) and supported a license application by the DOE to the U.S. Nuclear Regulatory Commission (NRC) for the construction of the YM repository (2). This presentation provides an overview of the conceptual and computational structure of the indicated PA (hereafter referred to as the 2008 YM PA) and the roles that uncertainty analysis and sensitivity analysis play in this structure.

Shop Class for the Next Millenium: Education through Computer-Enriched Handicrafts

OpenAIRE

Eisenberg, Mike; Eisenberg, Ann Nishioka

1998-01-01

In this paper we use our experiences with the HyperGami program as a springboard for a broader look at the future of computationally-enriched handicrafts. HyperGami is an educational application for the design and construction of mathematical models and sculptures in paper; as such, it serves as a source of examples and insights for the more general problem of how to integrate the "high-tech" features of computation with the "low-tech" features of traditional craft materials in education. We ...

Large-N limit of the non-local 2D Yang-Mills and generalized Yang-Mills theories on a cylinder

Energy Technology Data Exchange (ETDEWEB)

Saaidi, K. [Department of Physics, Tehran University (Iran); Khorrami, M. [Institute for Advanced Studies in Basic Sciences, Zanjan (Iran)

2002-04-01

The large-group behavior of the non-local YM{sub 2}'s and gYM{sub 2}'s on a cylinder or a disk is investigated. It is shown that this behavior is similar to that of the corresponding local theory, but with the area of the cylinder replaced by an effective area depending on the dominant representation. The critical areas for non-local YM{sub 2}'s on a cylinder with some special boundary conditions are also obtained. (orig.)

Radiating black holes in Einstein-Yang-Mills theory and cosmic censorship

International Nuclear Information System (INIS)

Ghosh, Sushant G.; Dadhich, Naresh

2010-01-01

Exact nonstatic spherically symmetric black-hole solutions of the higher dimensional Einstein-Yang-Mills equations for a null dust with Yang-Mills gauge charge are obtained by employing Wu-Yang ansatz, namely, HD-EYM Vaidya solution. It is interesting to note that gravitational contribution of Yang-Mills (YM) gauge charge for this ansatz is indeed opposite (attractive rather than repulsive) that of Maxwell charge. It turns out that the gravitational collapse of null dust with YM gauge charge admits strong curvature shell focusing naked singularities violating cosmic censorship. However, there is significant shrinkage of the initial data space for a naked singularity of the HD-Vaidya collapse due to presence of YM gauge charge. The effect of YM gauge charge on structure and location of the apparent and event horizons is also discussed.

Time, Calendar and Millenium

Indian Academy of Sciences (India)

summer to summer, was made as 360 days and the lunar month as nearly 30 days. ..... and workers in England, who felt that they were being cheated 11 days of .... to Indian scholars earlier, became known in Europe only by the. 12th century ...

Conversion of the former uranium producer into a redevelopment company with limited liability and social problems to be solved by the company

International Nuclear Information System (INIS)

Scheid, R.

1997-01-01

The activities of the Soviet/German company SDAG Wismut were discontinued after the German/Russian treaty of 16 May 1991. The ADAG Wismut was converted into the redevelopment company WISMUT GmbH. This was a task involving aspects of international law, company law, structural policy, engineering and technology, and social aspects which will go on well beyond the turn of the millenium. Separate departments were established for redevelopment, services to be privatized, and promotion of employment. The founding of societies for promotion of employment was an important and successful instrument of socially acceptable staff reduction. The know-how gained during the reconstruction procedure may be marketed successfully on an international scale. (orig.) [de

An Optical Encryption and Decryption Method and System

DEFF Research Database (Denmark)

2000-01-01

The invention relates to securing of information utilising optical imaging technologies and more specifically to phase encryption and decryption of images. An image is encrypted into a mask having a plurality of mask resolution elements (Xm, Ym) by encoding the image using e.g. a phase mask with ...... modulator resolution elements, the decrypting phase value phi d (Xd, Yd) and the decrypting amplitude value ad (Xd, Yd) respectively, of a modulator resolution element (Xd, Yd) being substantially equal to - phi c (Xm, Ym) and ac (Xm, Ym)....

Expected dose for the early failure scenario classes in the 2008 performance assessment for the proposed high-level radioactive waste repository at Yucca Mountain, Nevada

International Nuclear Information System (INIS)

Helton, J.C.; Hansen, C.W.; Sallaberry, C.J.

2014-01-01

Extensive work has been carried out by the U.S. Department of Energy (DOE) in the development of a proposed geologic repository at Yucca Mountain (YM), Nevada, for the disposal of high-level radioactive waste. In support of this development and an associated license application to the U.S. Nuclear Regulatory Commission (NRC), the DOE completed an extensive performance assessment (PA) for the proposed YM repository in 2008. This presentation describes the determination of expected dose to the reasonably maximally exposed individual (RMEI) specified in the NRC regulations for the YM repository for the early waste package (WP) failure scenario class and the early drip shield (DS) failure scenario class in the 2008 YM PA. The following topics are addressed: (i) properties of the early failure scenario classes and the determination of dose and expected dose the RMEI, (ii) expected dose and uncertainty in expected dose to the RMEI from the early WP failure scenario class, (iii) expected dose and uncertainty in expected dose to the RMEI from the early DS failure scenario class, (iv) expected dose and uncertainty in expected dose to the RMEI from the combined early WP and early DS failure scenario class with and without the inclusion of failures resulting from nominal processes, and (v) uncertainty in the occurrence of early failure scenario classes. The present article is part of a special issue of Reliability Engineering and System Safety devoted to the 2008 YM PA; additional articles in the issue describe other aspects of the 2008 YM PA. - Highlights: • Extensive work has been carried out by the U.S. DOE in the development of a proposed geologic repository at Yucca Mountain (YM), Nevada, for the disposal of high-level radioactive waste. • Properties of the early failure scenario classes (i.e. early waste package failure and early drip shield failure) in the 2008 YM performance assessment are described. • Determination of dose, expected dose and expected (mean

Development of live attenuated Streptococcus agalactiae vaccine for tilapia via continuous passage in vitro.

Science.gov (United States)

Li, L P; Wang, R; Liang, W W; Huang, T; Huang, Y; Luo, F G; Lei, A Y; Chen, M; Gan, X

2015-08-01

Fish Streptococcus agalactiae (S. agalactiae) seriously harms the world's aquaculture industry and causes huge economic losses. This study aimed to develop a potential live attenuated vaccine of S. agalactiae. Pre-screened vaccine candidate strain S. agalactiae HN016 was used as starting material to generate an attenuated strain S. agalactiae YM001 by continuous passage in vitro. The biological characteristics, virulence, and stability of YM001 were detected, and the protective efficacy of YM001 immunization in tilapia was also determined. Our results indicated that the growth, staining, characteristics of pulsed-field gel electrophoresis (PFGE) genotype, and virulence of YM001 were changed significantly as compared to the parental strain HN016. High doses of YM001 by intraperitoneal (IP) injection (1.0 × 10(9) CFU/fish) and oral gavage (1.0 × 10(10) CFU/fish) respectively did not cause any mortality and morbidity in tilapia. The relative percent survivals (RPSs) of fishes immunized with YM001 (1.0 × 10(8) CFU/fish, one time) via injection, immersion, and oral administration were 96.88, 67.22, and 71.81%, respectively, at 15 days, and 93.61, 60.56, and 53.16%, respectively, at 30 days. In all tests with 1-3 times of immunization in tilapia, the dosages at 1 × 10(8) and 1 × 10(9) CFU/fish displayed the similar best results, whereas the immunoprotection of the dosages at 1 × 10(6) and 1 × 10(7) CFU/fish declined significantly (P 0.05). The level of protective antibody elicited by oral immunization was significantly higher compared to that of the control group (P S. agalactiae strain YM001; oral immunization of tilapia with this strain produced a good immune protection. Copyright © 2015 Elsevier Ltd. All rights reserved.

Uma Análise da Aplicação de Três Métodos Estatísticos para o Cálculo do Desvio Padrão da Direção do Vento na Região Tropical

Directory of Open Access Journals (Sweden)

Adaiana Francisca Gomes da Silva

2016-03-01

Full Text Available Resumo Neste trabalho é apresentada uma revisão sobre métodos para cálculo do desvio padrão da direção do vento horizontal (σθ. Três diferentes métodos clássicos encontrados na literatura [Verral e Williams, 1982 (VW, Ackermann, 1983 (ACK, e Yamartino, 1984 (YM] são avaliados a partir de intercomparação entre eles utilizando-se dados de vento obtidos por radiossondagens. Estas medidas foram realizadas a cada seis horas durante um período de 11 dias do mês de setembro de 2008 (estação seca da região Norte do NE do Brasil, com ventos alísios intensos. Os cálculos mostraram que o método de YM apresentou-se o mais confiável, sendo que os resultados de VW foram muito próximos de YM. Comparando os métodos dois a dois, as máximas diferenças foram de 29 graus entre ACK e YM e 26,3 graus entre ACK e VW, enquanto que entre YM e VW a máxima diferença foi de apenas 2,6 graus. Segundo a literatura revisada, YM é o método mais estável ao longo da variação de σθ, com erro de, no máximo, 2%.

Uncertainty and sensitivity analysis in performance assessment for the proposed high-level radioactive waste repository at Yucca Mountain, Nevada

International Nuclear Information System (INIS)

Helton, Jon C.; Hansen, Clifford W.; Sallaberry, Cédric J.

2012-01-01

Extensive work has been carried out by the U.S. Department of Energy (DOE) in the development of a proposed geologic repository at Yucca Mountain (YM), Nevada, for the disposal of high-level radioactive waste. As part of this development, a detailed performance assessment (PA) for the YM repository was completed in 2008 and supported a license application by the DOE to the U.S. Nuclear Regulatory Commission (NRC) for the construction of the YM repository. The following aspects of the 2008 YM PA are described in this presentation: (i) conceptual structure and computational organization, (ii) uncertainty and sensitivity analysis techniques in use, (iii) uncertainty and sensitivity analysis for physical processes, and (iv) uncertainty and sensitivity analysis for expected dose to the reasonably maximally exposed individual (RMEI) specified the NRC’s regulations for the YM repository. - Highlights: ► An overview of performance assessment for the proposed Yucca Mountain radioactive waste repository is presented. ► Conceptual structure and computational organization are described. ► Uncertainty and sensitivity analysis techniques are described. ► Uncertainty and sensitivity analysis results for physical processes are presented. ► Uncertainty and sensitivity analysis results for expected dose are presented.

A Discontinuous Galerkin Finite Element Method for Dynamic of Fully Saturated Soil / Rzwiazanie Zadania Dynamiki Całkowicie Nawodnionego Gruntu Przy Zastosowaniu Mes Z Nieciagłym Sformułowaniem Galerkina W Czasie

Directory of Open Access Journals (Sweden)

Wrana B.

2011-03-01

Full Text Available Artykuł podejmuje zagadnienie analizy rozchodzenia sie fal naprezeniowych w gruncie w ujeciu metody elementów skonczonych bazujac na sformułowaniu rozwiazania ciagłego w przestrzeni i nieciagłego w dziedzinie czasu Galerkina (space and time-discontinous Galerkin TDG finite element method. W tym sformułowaniu zarówno przemieszczenia jak i predkosci sa wielkosciami nieznanymi wzajemnie niezaleznymi aproksymowanymi ciagłymi funkcjami kształtu w przestrzeni i nieciagłymi funkcjami kształtu w czasie. Do opisu zachowania sie gruntu w pełni nasyconego woda zastosowano sformułowanie u-p w ujeciu metody elementów skonczonych. Grunt traktowany jest, jako osrodek dwufazowy składajacy sie ze szkieletu i wody w porach. Zastosowane sformułowanie uwzglednia tłumienie osrodka przez uwzglednienie dyssypacji energii proporcjonalnej do predkosci wody wzgledem szkieletu. W artykule przedstawiono porównanie proponowanej metody rozwiazania numerycznego w dziedzinie czasu do metod obecnie stosowanych, takich jak: metoda róznicy centralnej, metoda Houbolta, Wilsona θ, HHT-α oraz najczesciej stosowanej metody Newmarka. Z porównania wynika, ze proponowana metoda jest metoda stabilna o małym błedzie numerycznego rozwiazania.

The state equation of Yang-Mills field dark energy models

International Nuclear Information System (INIS)

Zhao Wen; Zhang Yang

2006-01-01

In this paper, we study the possibility of building Yang-Mills (YM) field dark energy models with equation of state (EoS) crossing -1, and find that it cannot be realized by the single YM field models, no matter what kind of Lagrangian or initial condition. But the states of -1 -1 to <-1, and it will go to the critical state of ω = -1 with the expansion of the universe, which character is the same as the single YM field models, and the big rip is naturally avoided

Uncertainty and Sensitivity of Contaminant Travel Times from the Upgradient Nevada Test Site to the Yucca Mountain Area

Energy Technology Data Exchange (ETDEWEB)

J. Zhu; K. Pohlmann; J. Chapman; C. Russell; R.W.H. Carroll; D. Shafer

2009-09-10

Yucca Mountain (YM), Nevada, has been proposed by the U.S. Department of Energy as the nation’s first permanent geologic repository for spent nuclear fuel and highlevel radioactive waste. In this study, the potential for groundwater advective pathways from underground nuclear testing areas on the Nevada Test Site (NTS) to intercept the subsurface of the proposed land withdrawal area for the repository is investigated. The timeframe for advective travel and its uncertainty for possible radionuclide movement along these flow pathways is estimated as a result of effective-porosity value uncertainty for the hydrogeologic units (HGUs) along the flow paths. Furthermore, sensitivity analysis is conducted to determine the most influential HGUs on the advective radionuclide travel times from the NTS to the YM area. Groundwater pathways are obtained using the particle tracking package MODPATH and flow results from the Death Valley regional groundwater flow system (DVRFS) model developed by the U.S. Geological Survey (USGS). Effectiveporosity values for HGUs along these pathways are one of several parameters that determine possible radionuclide travel times between the NTS and proposed YM withdrawal areas. Values and uncertainties of HGU porosities are quantified through evaluation of existing site effective-porosity data and expert professional judgment and are incorporated in the model through Monte Carlo simulations to estimate mean travel times and uncertainties. The simulations are based on two steady-state flow scenarios, the pre-pumping (the initial stress period of the DVRFS model), and the 1998 pumping (assuming steady-state conditions resulting from pumping in the last stress period of the DVRFS model) scenarios for the purpose of long-term prediction and monitoring. The pumping scenario accounts for groundwater withdrawal activities in the Amargosa Desert and other areas downgradient of YM. Considering each detonation in a clustered region around Pahute Mesa (in

Uncertainty and Sensitivity of Contaminant Travel Times from the Upgradient Nevada Test Site to the Yucca Mountain Area

International Nuclear Information System (INIS)

Zhu, J.; Pohlmann, K.; Chapman, J.; Russell, C.; Carroll, R.W.H.; Shafer, D.

2009-01-01

Yucca Mountain (YM), Nevada, has been proposed by the U.S. Department of Energy as the nation's first permanent geologic repository for spent nuclear fuel and high-level radioactive waste. In this study, the potential for groundwater advective pathways from underground nuclear testing areas on the Nevada Test Site (NTS) to intercept the subsurface of the proposed land withdrawal area for the repository is investigated. The timeframe for advective travel and its uncertainty for possible radionuclide movement along these flow pathways is estimated as a result of effective-porosity value uncertainty for the hydrogeologic units (HGUs) along the flow paths. Furthermore, sensitivity analysis is conducted to determine the most influential HGUs on the advective radionuclide travel times from the NTS to the YM area. Groundwater pathways are obtained using the particle tracking package MODPATH and flow results from the Death Valley regional groundwater flow system (DVRFS) model developed by the U.S. Geological Survey (USGS). Effective porosity values for HGUs along these pathways are one of several parameters that determine possible radionuclide travel times between the NTS and proposed YM withdrawal areas. Values and uncertainties of HGU porosities are quantified through evaluation of existing site effective-porosity data and expert professional judgment and are incorporated in the model through Monte Carlo simulations to estimate mean travel times and uncertainties. The simulations are based on two steady-state flow scenarios, the pre-pumping (the initial stress period of the DVRFS model), and the 1998 pumping (assuming steady-state conditions resulting from pumping in the last stress period of the DVRFS model) scenarios for the purpose of long-term prediction and monitoring. The pumping scenario accounts for groundwater withdrawal activities in the Amargosa Desert and other areas downgradient of YM. Considering each detonation in a clustered region around Pahute Mesa (in

Correlation analysis of renal ultrasound elastography and clinical and pathological changes in patients with chronic kidney disease
.

Science.gov (United States)

Peng, Lingyan; Zhong, Tingting; Fan, Qiuling; Liu, Yanjun; Wang, Xuemei; Wang, Lining

2017-06-01

To analyze the correlations of renal tissue elastography with clinical biochemical indicators and pathological changes in patients with chronic kidney disease (CKD) as well as to explore the potential for renal tissue elastography as a new, noninvasive method for the dynamic monitoring of renal disease progression, efficacy assessment, and prognosis evaluation. Patients admitted to the Department of Nephrology of the First Affiliated Hospital of China Medical University from August 2014 to January 2015 who had undergone renal biopsies were selected. A total of 113 patients with CKD and 16 healthy controls were enrolled in this study, including 61 males and 52 females. In total, 23 cases of IgA nephropathy, 39 cases of membranous nephropathy, 15 cases of minimal-change nephropathy (MCN), and 7 cases of focal segmental glomerulosclerosis were included. The Young's moduli (YM) of the renal cortex and medulla were measured using an AixPlorer Doppler ultrasound with full digital color from Supersonic Imagine. The correlations between the YM of renal tissue and clinical biochemical indicators of blood and urine and the differences in Young's moduli among the different pathological changes in the patients with CKD were analyzed. The YM of the CKD patients was significantly higher than that of the control group (p < 0.05), and the YM of the renal cortex and medulla gradually increased with the progression of CKD. The YM of the renal cortex in the stage-G5 CKD patients was significantly higher than that of the CKD patients in stages G1 - G3 (p < 0.05). The YM of the renal medulla of the CKD patients in stages G3 - 5 was significantly higher than that of the CKD patients in stages G1 - G2. On univariate analysis, the YM of the renal cortex was correlated with systolic blood pressure, serum creatinine, cystatin C, serum albumin, serum phosphorus, calcium and phosphorus products, uric acid, iPTH, urinary N-acetyl-glucosaminidase (NAG), eGFR, and hemoglobin levels. And

Characterization, propagation and analysis of aleatory and epistemic uncertainty in the 2008 performance assessment for the proposed repository for radioactive waste at Yucca Mountain, Nevada

International Nuclear Information System (INIS)

Helton, Jon Craig; Sallaberry, Cedric M.; Hansen, Clifford W.

2010-01-01

The 2008 performance assessment (PA) for the proposed repository for high-level radioactive waste at Yucca Mountain (YM), Nevada, illustrates the conceptual structure of risk assessments for complex systems. The 2008 YM PA is based on the following three conceptual entities: a probability space that characterizes aleatory uncertainty; a function that predicts consequences for individual elements of the sample space for aleatory uncertainty; and a probability space that characterizes epistemic uncertainty. These entities and their use in the characterization, propagation and analysis of aleatory and epistemic uncertainty are described and illustrated with results from the 2008 YM PA.

Spinning higher dimensional Einstein-Yang-Mills black holes

International Nuclear Information System (INIS)

Ghosh, Sushant G.; Papnoi, Uma

2014-01-01

We construct a Kerr-Newman-like spacetime starting from higher dimensional (HD) Einstein-Yang-Mills black holes via complex transformations suggested by Newman-Janis. The new metrics are a HD generalization of Kerr-Newman spacetimes which has a geometry that is precisely that of Kerr-Newman in 4D corresponding to a Yang-Mills (YM) gauge charge, but the sign of the charge term gets flipped in the HD spacetimes. It is interesting to note that the gravitational contribution of the YM gauge charge, in HD, is indeed opposite (attractive rather than repulsive) to that of the Maxwell charge. The effect of the YM gauge charge on the structure and location of static limit surface and apparent horizon is discussed. We find that static limit surfaces become less prolate with increase in dimensions and are also sensitive to the YM gauge charge, thereby affecting the shape of the ergosphere. We also analyze some thermodynamical properties of these BHs. (orig.)

Spinning higher dimensional Einstein-Yang-Mills black holes

Energy Technology Data Exchange (ETDEWEB)

Ghosh, Sushant G. [Jamia Millia Islamia, Centre for Theoretical Physics, New Delhi (India); University of Kwa-Zulu-Natal, Astrophysics and Cosmology Research Unit, School of Mathematical Sciences, Private Bag 54001, Durban (South Africa); Papnoi, Uma [Jamia Millia Islamia, Centre for Theoretical Physics, New Delhi (India)

2014-08-15

We construct a Kerr-Newman-like spacetime starting from higher dimensional (HD) Einstein-Yang-Mills black holes via complex transformations suggested by Newman-Janis. The new metrics are a HD generalization of Kerr-Newman spacetimes which has a geometry that is precisely that of Kerr-Newman in 4D corresponding to a Yang-Mills (YM) gauge charge, but the sign of the charge term gets flipped in the HD spacetimes. It is interesting to note that the gravitational contribution of the YM gauge charge, in HD, is indeed opposite (attractive rather than repulsive) to that of the Maxwell charge. The effect of the YM gauge charge on the structure and location of static limit surface and apparent horizon is discussed. We find that static limit surfaces become less prolate with increase in dimensions and are also sensitive to the YM gauge charge, thereby affecting the shape of the ergosphere. We also analyze some thermodynamical properties of these BHs. (orig.)

Evaluation Of Groundwater Pathways And Travel Times From The Nevada Test Site To The Potential Yucca Mountain Repository

International Nuclear Information System (INIS)

K.F. Pohlman; J. Zhu; M. Ye; J. Chapman; C. Russell; D.S. Shafer

2006-01-01

Yucca Mountain (YM), Nevada, has been recommended as a deep geological repository for the disposal of spent fuel and high-level radioactive waste. If YM is licensed as a repository by the Nuclear Regulatory Commission, it will be important to identify the potential for radionuclides to migrate from underground nuclear testing areas located on the Nevada Test Site (NTS) to the hydraulically downgradient repository area to ensure that monitoring does not incorrectly attribute repository failure to radionuclides originating from other sources. In this study, we use the Death Valley Regional Flow System (DVRFS) model developed by the U.S. Geological Survey to investigate potential groundwater migration pathways and associated travel times from the NTS to the proposed YM repository area. Using results from the calibrated DVRFS model and the particle tracking post-processing package MODPATH, we modeled three-dimensional groundwater advective pathways in the NTS and YM region. Our study focuses on evaluating the potential for groundwater pathways between the NTS and YM withdrawal area and whether travel times for advective flow along these pathways coincide with the prospective monitoring timeframe at the proposed repository. We include uncertainty in effective porosity, as this is a critical variable in the determination of time for radionuclides to travel from the NTS region to the YM withdrawal area. Uncertainty in porosity is quantified through evaluation of existing site data and expert judgment and is incorporated in the model through Monte Carlo simulation. Since porosity information is limited for this region, the uncertainty is quite large and this is reflected in the results as a large range in simulated groundwater travel times

ABSTRACT: CONTAMINANT TRAVEL TIMES FROM THE NEVADA TEST SITE TO YUCCA MOUNTAIN: SENSITIVITY TO POROSITY

International Nuclear Information System (INIS)

Karl F. Pohlmann; Jianting Zhu; Jenny B. Chapman; Charles E. Russell; Rosemary W. H. Carroll; David S. Shafer

2008-01-01

Yucca Mountain (YM), Nevada, has been proposed by the U.S. Department of Energy as a geologic repository for spent nuclear fuel and high-level radioactive waste. In this study, we investigate the potential for groundwater advective pathways from underground nuclear testing areas on the Nevada Test Site (NTS) to the YM area by estimating the timeframe for advective travel and its uncertainty resulting from porosity value uncertainty for hydrogeologic units (HGUs) in the region. We perform sensitivity analysis to determine the most influential HGUs on advective radionuclide travel times from the NTS to the YM area. Groundwater pathways and advective travel times are obtained using the particle tracking package MODPATH and flow results from the Death Valley Regional Flow System (DVRFS) model by the U.S. Geological Survey. Values and uncertainties of HGU porosities are quantified through evaluation of existing site porosity data and expert professional judgment and are incorporated through Monte Carlo simulations to estimate mean travel times and uncertainties. We base our simulations on two steady state flow scenarios for the purpose of long term prediction and monitoring. The first represents pre-pumping conditions prior to groundwater development in the area in 1912 (the initial stress period of the DVRFS model). The second simulates 1998 pumping (assuming steady state conditions resulting from pumping in the last stress period of the DVRFS model). Considering underground tests in a clustered region around Pahute Mesa on the NTS as initial particle positions, we track these particles forward using MODPATH to identify hydraulically downgradient groundwater discharge zones and to determine which flowpaths will intercept the YM area. Out of the 71 tests in the saturated zone, flowpaths of 23 intercept the YM area under the pre-pumping scenario. For the 1998 pumping scenario, flowpaths from 55 of the 71 tests intercept the YM area. The results illustrate that mean

Colour-kinematics duality and the Drinfeld double of the Lie algebra of diffeomorphisms

Energy Technology Data Exchange (ETDEWEB)

Fu, Chih-Hao; Krasnov, Kirill [School of Mathematical Sciences, The University of Nottingham,University Park, Nottingham NG7 2RD (United Kingdom)

2017-01-17

Colour-kinematics duality suggests that Yang-Mills (YM) theory possesses some hidden Lie algebraic structure. So far this structure has resisted understanding, apart from some progress in the self-dual sector. We show that there is indeed a Lie algebra behind the YM Feynman rules. The Lie algebra we uncover is the Drinfeld double of the Lie algebra of vector fields. More specifically, we show that the kinematic numerators following from the YM Feynman rules satisfy a version of the Jacobi identity, in that the Jacobiator of the bracket defined by the YM cubic vertex is cancelled by the contribution of the YM quartic vertex. We then show that this Jacobi-like identity is in fact the Jacobi identity of the Drinfeld double. All our considerations are off-shell. Our construction explains why numerators computed using the Feynman rules satisfy the colour-kinematics at four but not at higher numbers of points. It also suggests a way of modifying the Feynman rules so that the duality can continue to hold for an arbitrary number of gluons. Our construction stops short of producing explicit higher point numerators because of an absence of a certain property at four points. We comment on possible ways of correcting this, but leave the next word in the story to future work.

Utilization of flax (Linum usitatissimum) cellulose nanocrystals as reinforcing material for chitosan films.

Science.gov (United States)

Mujtaba, Muhammad; Salaberria, Asier M; Andres, María A; Kaya, Murat; Gunyakti, Ayse; Labidi, Jalel

2017-11-01

Use of plastic based packaging tools is causing both health and economic problems. To overcome this situation, researchers are focusing on the use of different biomaterials such as chitosan and cellulose. The current study was conducted to check the effect of flax (Linum usitatissimum) cellulose nanocrystals (CNC) on mechanical and barrier properties of chitosan-based films. CNC was incorporated in different concentrations (5, 10, 20 and 30%). CNC was isolated from flax fiber using acid hydrolysis method. Tensile strength (TS) and young modulus (YM) values increased with the increase of CNC concentration. Chitosan film with 20% CNC revealed the highest YM value as 52.35MPa. No significant improvement was recorded in water vapor permeability due to overall lower film crystallinity. All the films were observed to be transparent up to an acceptable level. SEM and AFM analysis confirmed the homogeneity of films. A gradual enhancement was recorded in the antimicrobial activity of chitosan/CNC composite films. No significant improvement revealed in the thermal stability of composites. Copyright © 2017 Elsevier B.V. All rights reserved.

Quantitative measurement of post-irradiation neck fibrosis based on the young modulus: description of a new method and clinical results.

Science.gov (United States)

Leung, Sing-Fai; Zheng, Yongping; Choi, Charles Y K; Mak, Suzanne S S; Chiu, Samuel K W; Zee, Benny; Mak, Arthur F T

2002-08-01

Postirradiation fibrosis is one of the most common late effects of radiation therapy for patients with head and neck carcinoma. An objective and quantitative method for its measurement is much desired, but the criteria currently used to score fibrosis are mostly semiquantitative and partially subjective. The Young Modulus (YM) is a physical parameter that characterizes the deformability of material to stress. The authors measured the YM in soft tissues of the neck, at defined reference points, using an ultrasound probe and computer algorithm that quantified the indentation (deformation) on tissue due to a measured, applied force. One hundred five patients who had received previous radiation therapy to the entire neck were assessed, and the results were compared with the hand palpation scores and with a functional parameter represented by the range of neck rotation, and all results were correlated with symptoms. The YM was obtained successfully in all patients examined. It had a significant positive correlation with the palpation score and a significant negative correlation with the range of neck rotation. The YM was significantly higher on the side of the neck that received a boost dose of radiation, although the corresponding palpation scores were similar. The results of all three measurement methods were correlated with symptoms. Postirradiation neck fibrosis can be measured in absolute units based on the YM. The results showed a significant correlation with hand palpation scores, with restriction of neck rotation, and with symptoms. Compared with the palpation method, the YM is more quantitative, objective, focused on small subregions, and better discriminates regions subject to differential radiation dose levels. Its inclusion in the Analytic category of the Late Effects of Normal Tissues-SOMA system should be considered to facilitate comparative studies. Copyright 2002 American Cancer Society.

Management of dams for the next Millennium: proceedings of the 1999 Canadian Dam Association

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-07-01

The meeting featured seven sessions with 18 papers abstracted/indexed therein as follows: keynote address: tailings dams safety - implications for the dam safety community; 1 - design and performance: performance monitoring of dams: are we doing what we should be doing?; tailings dams from the perspective of conventional dam engineering; and design overview of Syncrude's Mildred Lake east toe berm; 2 - design and modelling: use of a 2D model for a dam break study on the ALCAN hydroelectric complex in Quebec; and spillway design implications resulting from changes in rainfall extremes; 3 - risk and dam safety I: closing the gaps in the dam safety guidelines; the reality of life safety consequence classification; and surveillance practices for the next millenium; 4 - risk and dam safety II: quantitative risk-assessment using the capacity-demand analysis; and new guidelines for dam safety classification; 5 - millenium issues: expectations of immortality, dam safety management into the next millenium; 6 - rehabilitation techniques: the unconventional application of conventional materials; nondestructive testing technology to characterize concrete dam/bedrock interface; method and instrument for detecting crack in concrete; and grouting of the cracks in the Arch 5-6 - Daniel Johnson Dam; and 7 - case studies: rehabilitation of an 80 year old Ambursen type dam; and debris booms for the protection of spillways.

Energy for a new millenium

International Nuclear Information System (INIS)

Teller, E.

1981-01-01

In an historically oriented presentation the author shows how today's energy situation has come about, how this situation is conditioned in detail, and which possibilities there are for the future. The technology, the efficiency as well as advantages and risks are compared which are related to the energy carriers like petroleum, natural gas, coal, sun, wind, tides, water power, water and ground heat, nuclear power, and fuel cells. The financial expenditure resp. the efficiency of four basic decisions are compared for the planning of the next steps, continuation of past and present energy policy, curbed growth, forced growth, or the internationalization of the competition with the oil-importing countries. The author tries to render the discussions on the energy situation sensible by scientific arguments. His analyses culminate in a model for the future. (UA) [de

Russia at the beginning of 3rd millenium. Geopolitical resources and options

Directory of Open Access Journals (Sweden)

Adrian Botezatu

2012-07-01

Full Text Available The authors present and analyze demographic and economic resources of Russia and also its geopolitical options, favored by the control of these resources. Geopolithically, nowadays Russia has great difficulties when it comes to demography, because of the decrease of birth rate, to the poor demographic density, low life expectancy and its population’s precarious general health state. All the same, nowadays Russia is the richest country in the world. Based on these considerations, the authors consider that Rusia could become a true super-power (according to Zbigniew Brzezinski’s considerations only if it will solve its demographical problems and will build a Western-style army and economy, based on its huge economic resources.

The Chern-Simons diffusion rate in improved holographic QCD

NARCIS (Netherlands)

Gürsoy, U.; Iatrakis, I.; Kiritsis, E.; Nitti, F.; O’Bannon, A.

2013-01-01

In (3 + 1)-dimensional SU(N c) Yang-Mills (YM) theory, the Chern-Simons diffusion rate, ΓCS, is determined by the zero-momentum, zero-frequency limit of the retarded two-point function of the CP-odd operator tr [F ∧ F ], with F the YM field strength. The Chern-Simons diffusion rate is a crucial

Coulomb branches with complex singularities

Science.gov (United States)

Argyres, Philip C.; Martone, Mario

2018-06-01

We construct 4d superconformal field theories (SCFTs) whose Coulomb branches have singular complex structures. This implies, in particular, that their Coulomb branch coordinate rings are not freely generated. Our construction also gives examples of distinct SCFTs which have identical moduli space (Coulomb, Higgs, and mixed branch) geometries. These SCFTs thus provide an interesting arena in which to test the relationship between moduli space geometries and conformal field theory data. We construct these SCFTs by gauging certain discrete global symmetries of N = 4 superYang-Mills (sYM) theories. In the simplest cases, these discrete symmetries are outer automorphisms of the sYM gauge group, and so these theories have lagrangian descriptions as N = 4 sYM theories with disconnected gauge groups.

Evaluation of Personal Chemical Vapor Protection for Patrol and Tactical Law Enforcement

National Research Council Canada - National Science Library

Fedele, Paul D; Lake, William L; Arca, Victor J; Marshall, Stephen M; Mitchell, David B

2002-01-01

... functions in law enforcement. Various Level C, impermeable and charcoal impregnated, vapor-absorptive, air-permeable protective clothing ensembles, worn with the MSA Millenium respiratory protective mask/butyl hood, and seven-mil...

Pre-hospital management and risk factors in children with acute ...

African Journals Online (AJOL)

2013-09-04

Sep 4, 2013 ... and mortality in children, especially in developing countries. ... towards achieving Millenium Development Goal 4 by 2015.[4]. In 1980 the ..... Human Development International Site Development Initiative Perinatal Study.

A contingency safe, responsible, economic, increased capacity spent nuclear fuel (SNF) advance fuel cycle

International Nuclear Information System (INIS)

Levy, S.

2008-01-01

The purpose of this paper is to have an Advanced Light Water (LWR) fuel cycle and an associated development program to provide a contingency plan to the current DOE effort to license once-through spent Light Water Reactor (LWR) fuel for disposition at Yucca Mountain (YM). The intent is to fully support the forthcoming June 2008 DOE submittal to the Nuclear Regulatory Commission (NRC) based upon the latest DOE draft DOE/EIS-0250F-SID dated October 2007 which shows that the latest DOE YM doses would readily satisfy the anticipated NRC and Environmental Protection Agency (EP) standards. The proposed Advance Fuel Cycle can offer potential resolution of obstacles that might arise during the NRC review and, particularly, during the final hearings process to be held in Nevada. Another reason for the proposed concept is that a substantial capacity growth of the YM repository will be necessary to accommodate the SNF of Advance Light Water Reactors (ALWRs) currently under consideration for United States (U.S.) electricity production (1) and the results of the recently issued study by the Electric Power Research Institute (EPRI) to reduce CO 2 emissions (2). That study predicts that by 2030 U.S. nuclear power generation would grow by 64 Gigawatt electrical (GWe) and account for 25.5 percent of the overall U.S. electrical generation. The current annual SNF once-through fuel cycle accumulation would rise from 2000-2100 MT (Metric Tons) to about 3480 MT in 2030 and the total SNF inventory, would reach nearly 500,000 MT by 2100 if U. S. nuclear power continues to grow at 1.1 percent per year after 2030. That last projection does not account for any SNF reduction due to increased fuel burnup or any increased capacity needed 'to establish supply Global Nuclear Energy Partnership (GNEP,) arrangements among nations to provide nuclear fuel and taking back spent fuel for recycling without spreading enrichment and reprocessing technologies' (3). The anticipated capacity of 120 MT

Phylogenetic and Physiological Diversity of Subseafloor Microbial Communities at Axial Seamount, Juan de Fuca Ridge: Summary of Results From the New Millenium Observatory (NeMO), 1998-2004

Science.gov (United States)

Baross, J. A.; Huber, J. A.; Mehta, M. P.; Opatkiewicz, A.; Bolton, S. A.; Butterfield, D. A.; Sogin, M. L.; Embley, R. W.

2005-12-01

Axial Seamount (45 ° 58' N; 130 ° 00' W) is an active submarine volcano located on the Juan de Fuca Ridge, approximately 300 miles off the coast of Oregon. Lying at the intersection of a seamount chain and a spreading axis, Axial is a unique study site from both the geological and biological perspective. In January of 1998, Axial experienced a week-long series of earthquakes, and subsequent water column and seafloor observations on the southeast portion of the caldera found temperature and chemical anomalies, extensive new seafloor lava flows, large "snow blower" type vents, and other characteristics commonly associated with diking-eruptive events. Due to its high activity and close proximity to shore, Axial was chosen as a site for a multi-year observatory (New Millenium Observatory, NeMO) to document changes and interactions between geology, chemistry, and biology on the mid-ocean ridge system. From 1998 through 2004, we extensively sampled diffuse vents at Axial Seamount to determine the physiological and phylogenetic diversity of subseafloor microbial communities and their relationship to the geochemical environment. Here we present a summary of those studies, including molecular-based phylogenetic surveys of bacteria, archaea, and potential nitrogen-fixing organisms, culturing results of thermophiles and hyperthermophiles from over 20 sites, and the distribution of one particular group of hyperthermophiles at diffuse vents throughout the caldera and how that distribution may be linked to the geochemical habitat. Results indicate that Axial supports a diverse subseafloor microbial community, including hydrogen and sulfur oxidizers, hyperthermophilic methane producers and heterotrophs, and many organisms with the potential to fix nitrogen. In addition, we find that the species composition of the microbial community changes in response to changes in the physical and chemical conditions at each vent site. The extent of seawater mixing with hydrothermal fluids

Age and sex differences in cerebral glucose consumption measured by pet using [18-F] fluorodeoxyglucose (FDG)

International Nuclear Information System (INIS)

Duara, R.; Barker, W.; Chang, J.; Apicella, A.; Finn, R.; Gilson, A.

1985-01-01

Resting cerebral glucose metabolic rates (CMRglc) were measured in 23 subjects by PET using FDG. Subjects were divided into several groups (mean age +- S.D.) 5 young males (YM) (27 +- 6); 6 young females (YF)(33 +9); 5 elderly males (EM)(73 +- 5); 7 elderly females (EF)(69 +- 7). Additionally, from these groups 4 YM, 3YF, 5EM and 4EF were studied again within 6 weeks under identical conditions. CMRglc in the YF group again was significantly hider than YM (p 0.05). No obvious relationships of CMRglc to the phase of the menstrual cycle was found in this small group. There was a trend (p=0.06) toward a higher CMRglc in YF than EF. These results support the findings of higher CBF in YF versus YM. The differences between the results of Kuhl et al (J. Cereb. and a reduction of CMRglc with age was found in a mixed group of males and females (58and female), and where no age effect was found the males, are also resolved by these findings. The authors suggest that the apparent age effect, in females in this study, is principally a hormonal one

Propiedades fisicoquímicas y aceptabilidad sensorial de yogur de leche descremada de cabra frutado con mango y plátano en pruebas aceleradas

Directory of Open Access Journals (Sweden)

Víctor Vásquez-Villalobos

2015-01-01

Full Text Available Dos tipos de yogur de leche descremada de cabra (3% de grasa frutado con mango (YM y plátano (YP fueron almacenados a temperaturas de 5 °C, 15 °C y 25 °C durante 72 horas. Cada 24 horas se analizó el pH, acidez titulable, sólidos totales, grasa y proteína. Asimismo se evaluó la aceptabilidad sensorial con 75 consumidores habituales de yogur, que respondieron con “sí” o “no” a la pregunta ¿consumiría este producto?. Al inicio, el pH, acidez, sólidos totales, grasa y proteína fue 4,35 y 4,36; 0,76% y 0,75%; 12,71% y 13,23%; 3,2% y 3,3%; 4,4% y 4,5%, respectivamente para el YM y el YP, cumpliendo con normas conocidas para yogur de leche de vaca: rango de acidez 0,5%-1,6%, grasa valor máximo 15% y proteína valor mínimo 2,7%. La aceptabilidad sensorial del YM y el YP fue alta, con 88,9% y 94,7%, respectivamente. Durante el almacenamiento en condiciones aceleradas, el pH disminuyó hasta 3,88 y 3,92; la acidez titulable aumentó hasta 1,1% y 0,93%; los sólidos totales, grasa y proteína disminuyeron hasta 9,37% y 9,7%; 2,4% y 2,0%; 2,5% y 2,6%, respectivamente para el YM y el YP, permaneciendo dentro de los límites de las normas consultadas. La aceptabilidad sensorial disminuyó hasta 4% y 5,33% para el YM y el YP respectivamente. Estimando así la vida útil de la aceptabilidad sensorial (V.U.A.S. a 4ºC en 69 y 49 h (para un porcentaje de rechazo de 25%, 193 y 111 h (para un porcentaje de rechazo de 50% para el YM y el YP respectivamente.

Astronomy and astrophysics in the new millennium: Panel reports

National Research Council Canada - National Science Library

Astronomy and Astrophysics Survey Committee, Board on Physics and Astronomy, Space Studies Board, National Research Council

2001-01-01

In preparing the report, Astronomy and Astrophysics in the New Millenium , the AASC made use of a series of panel reports that address various aspects of ground- and space-based astronomy and astrophysic...

Classical and quantum mechanics of non-abelian gauge fields

International Nuclear Information System (INIS)

Savvidy, G.K.

1984-01-01

Classical and quantum mechanics of non-abelian gauge fields are investigated both with and without spontaneous symmetry breaking. The fundamental subsystem (FS) of Yang-Mills classical mechanics (YMCM) is considered. It is shown to be a Kolmogorov K-system, and hence to have strong statistical properties. Integrable systems are also found, to which in terms of KAM theory Yang-Mills-Higgs classical mechanics (YMHCM) is close. Quantum-mechanical properties of the YM system and their relation to the problem of confinement are discussed. (orig.)

Selection and characterization of carotenoid-producing yeasts from Campinas region, Brazil Seleção e caracterização de leveduras produtoras decarotenóides na região de Campinas, Brasil

Directory of Open Access Journals (Sweden)

Iriani R. Maldonade

2007-03-01

Full Text Available The objective of the present study was to select and identify yeasts from Brazil capable of producing carotenoids. Pigmented yeasts were isolated from soil, leaves, fruits, flowers and a processed product. The samples were incubated at 30ºC in Erlenmeyer flasks, containing YM broth. After 48 hours, they were inoculated in Petri dishes with YM agar, and incubated at 30ºC during 120 hours. The yeast colonies, which presented yellow to red coloration, were transferred to culture tubes containing YM agar, and incubated at 30ºC for 72 hours. Out of 242 samples, only five had yellow to red color at high intensity. These highly pigmented yeasts were re-isolated in Petri dishes with YM agar and then transferred to tubes with GPYM agar. Identification through morphological and reproduction characteristics, along with physiological and biochemical tests, classified four strains as R. mucilaginosa and one strain as R. graminis. The main carotenoids extracted from them were identified through HPLC analysis as beta-carotene and torulene. The strains showed potential as promising microorganisms for the commercial production of carotenoids.Este trabalho teve como objetivo selecionar e identificar leveduras encontradas no Brasil capazes de produzir carotenóides. As leveduras pigmentadas foram isoladas de amostras de solos, folhas, frutos, flores e um alimento processado. As amostras foram colocadas em frascos de erlenmeyer, contendo meio de Extrato de Malte e Levedura (YM, e incubadas a 30ºC. Após 48 horas, as amostras foram inoculadas em placas de petri contendo meio YM ágar e incubadas a 30ºC por 120 horas. As colônias, que apresentaram coloração entre amarelo e vermelho, foram transferidas para os tubos de culturas, contendo meio YM ágar e incubadas a 30ºC por 72 horas. Das 242 amostras, somente cinco delas apresentaram coloração intensa entre amarelo e vermelho. Estas colônias de leveduras foram reisoladas, em placas de petri contendo YM �

Problem wolności w Internecie / The problem of freedom in Internet

Directory of Open Access Journals (Sweden)

Iwona Gleisner

2013-07-01

Full Text Available Artykuł jest próbą odpowiedzi na pytanie o granice wolności w Internecie. Dyskusje ten temat, toczące się na całym świecie od dawna, nie dały dotąd zadowalającej odpowiedzi. W ostatnich latach przybiera na sile spór pomiędzy zwolennikami pełnej swobody, a stronnikami prawnego ograniczania korzystania z zasobów globalnej sieci. Autorka przytacza argumenty obu stron konfliktu, zwracając uwagę na potrzebę znalezienia równowagi prawnej pomiędzy interesami twórców, a potrzebami odbiorców. Porusza ponadto istotne zagadnienie moralnej odpowiedzialności autorów za zamieszczane w Internecie treści.English abstractThis paper attempts to find an answer to the question about freedom in Internet. This issue has been discussed all over the world for long, however no satisfactory answer has yet been found. Recently, the dispute between the supporters of the full freedom and the ones voting for limiting the resources of the global network with legal means has been becoming more fierce. The author quotes arguments of both parties to the conflict, drawing attention to the need of finding a legal balance between the interests of the artists and the needs of the consumers. She also tackles with an important issue of moral responsibility of the authors for the contents placed in Internet. Normal 0 21 false false false PL X-NONE X-NONE

Evaluating DSM-5 Insomnia Disorder and the Treatment of Sleep Problems in a Psychiatric Population

Science.gov (United States)

Seow, Lee Seng Esmond; Verma, Swapna Kamal; Mok, Yee Ming; Kumar, Sunita; Chang, Sherilyn; Satghare, Pratika; Hombali, Aditi; Vaingankar, Janhavi; Chong, Siow Ann; Subramaniam, Mythily

2018-01-01

Study Objectives: With the introduction of insomnia disorder in Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), greater emphasis has been placed on the diagnosis and treatment of sleep disorder even in the presence of a coexisting mental disorder. The current study seeks to explore the clinical picture of insomnia in the context of psychiatric disorders commonly associated with sleep complaints by assessing the prevalence and correlates of DSM-5 insomnia disorder, and examining the extent to which insomnia symptoms have been addressed in this population. Methods: Four hundred treatment-seeking outpatients suffering from depressive, bipolar affective, anxiety, and schizophrenia spectrum disorders were recruited. DSM-5 insomnia was established using the modified Brief Insomnia Questionnaire. Differences in sociodemographic factors, clinical status, impairment outcomes, and mental health services utilization were compared. Information on patients' help-seeking experiences for insomnia-related symptoms was collected to determine the treatment received and treatment effectiveness. Results: Almost one-third of our sample (31.8%) had DSM-5 insomnia disorder. Those with insomnia disorder had significantly higher impairment outcomes than their counterparts but no group difference was observed for mental health services utilization. Findings based on past treatment contact for sleep problems suggest that diagnosis and treatment of insomnia is lacking in this population. Conclusions: With the new calling from DSM-5, clinicians treating psychiatric patients should view insomnia less as a symptom of their mental illnesses and treat clinical insomnia as a primary disorder. Patients should also be educated on the importance of reporting and treating their sleep complaints. Nonmedical (cognitive and behavioral) interventions for insomnia need to be further explored given their proven clinical effectiveness. Citation: Seow LSE, Verma SK, Mok YM, Kumar

Neutrino overview

International Nuclear Information System (INIS)

Haxton, W.C.

1994-01-01

I discuss some of the open issues in neutrino physics, emphasizing areas of intersection with astrophysics, that occupied the participants of the Snowmass Workshop on Nuclear and Particle Astrophysics and Cosmology in the Next Millenium

Integrated Tsunami Database: simulation and identification of seismic tsunami sources, 3D visualization and post-disaster assessment on the shore

Science.gov (United States)

Krivorot'ko, Olga; Kabanikhin, Sergey; Marinin, Igor; Karas, Adel; Khidasheli, David

2013-04-01

One of the most important problems of tsunami investigation is the problem of seismic tsunami source reconstruction. Non-profit organization WAPMERR (http://wapmerr.org) has provided a historical database of alleged tsunami sources around the world that obtained with the help of information about seaquakes. WAPMERR also has a database of observations of the tsunami waves in coastal areas. The main idea of presentation consists of determining of the tsunami source parameters using seismic data and observations of the tsunami waves on the shore, and the expansion and refinement of the database of presupposed tsunami sources for operative and accurate prediction of hazards and assessment of risks and consequences. Also we present 3D visualization of real-time tsunami wave propagation and loss assessment, characterizing the nature of the building stock in cities at risk, and monitoring by satellite images using modern GIS technology ITRIS (Integrated Tsunami Research and Information System) developed by WAPMERR and Informap Ltd. The special scientific plug-in components are embedded in a specially developed GIS-type graphic shell for easy data retrieval, visualization and processing. The most suitable physical models related to simulation of tsunamis are based on shallow water equations. We consider the initial-boundary value problem in Ω := {(x,y) ?R2 : x ?(0,Lx ), y ?(0,Ly ), Lx,Ly > 0} for the well-known linear shallow water equations in the Cartesian coordinate system in terms of the liquid flow components in dimensional form Here ?(x,y,t) defines the free water surface vertical displacement, i.e. amplitude of a tsunami wave, q(x,y) is the initial amplitude of a tsunami wave. The lateral boundary is assumed to be a non-reflecting boundary of the domain, that is, it allows the free passage of the propagating waves. Assume that the free surface oscillation data at points (xm, ym) are given as a measured output data from tsunami records: fm(t) := ? (xm, ym,t), (xm,ym

Investigation of long-term retention of unchanged (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, a novel "funny" If current channel inhibitor, and its metabolites in the eyeball and thoracic aorta of rats.

Science.gov (United States)

Umehara, Ken-ichi; Nakada, Naoyuki; Noguchi, Kiyoshi; Iwatsubo, Takafumi; Usui, Takashi; Kamimura, Hidetaka

2009-11-01

(-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel "funny" If current channel inhibitor, was being developed as a treatment for stable angina and atrial fibrillation. After a single oral administration of (14)C-YM758, extensive accumulation and long-term retention of radioactivity were observed in the eyeballs of nonalbino rats and in the thoracic aorta of albino/nonalbino rats. Radioluminograms of the eyeballs of nonalbino rats indicated that the radioactivity was localized to the uveal tract, which suggests that the radioactivity may be positively charged and bound mainly to the melanins. Treatment with a mixture of 2 mol/l hydrochloric acid and methanol (5:95, v/v) allowed for the recovery of the major portion of radioactivity from the eyeball, which suggests reversible binding. The radioactive constituents in eyeballs consisted of the unchanged drug (YM758) and three metabolites [mainly 6,7-dimethoxy-2-[(3R)-piperidin-3-ylcarbonyl]-1,2,3,4-tetrahydroisoquinoline (YM-252124)]. Using the organic solvent mixture described above, almost all of the radioactivity was not collected from the thoracic aorta, and approximately 90% was recovered by treatment with elastase, which suggests that some metabolites covalently bind to the elastin fiber localized in the tunica media.

Mechanical properties and collagen cross-linking of the patellar tendon in old and young men

DEFF Research Database (Denmark)

Couppé, C; Hansen, P; Kongsgaard, M

2009-01-01

were higher in OM than in YM (73 +/- 13 vs. 11 +/- 2 mmol/mol; P appreciably influence the dimensions or mechanical properties of the human patellar tendon in vivo. Collagen concentration was reduced, whereas both enzymatic......Age-related loss in muscle mass and strength impairs daily life function in the elderly. However, it remains unknown whether tendon properties also deteriorate with age. Cross-linking of collagen molecules provides structural integrity to the tendon fibrils and has been shown to change with age...... in animals but has never been examined in humans in vivo. In this study, we examined the mechanical properties and pyridinoline and pentosidine cross-link and collagen concentrations of the patellar tendon in vivo in old (OM) and young men (YM). Seven OM (67 +/- 3 years, 86 +/- 10 kg) and 10 YM (27 +/- 2...

BCJ numerators from reduced Pfaffian

Energy Technology Data Exchange (ETDEWEB)

Du, Yi-Jian [Center for Theoretical Physics, School of Physics and Technology, Wuhan University,No. 299 Bayi Road, Wuhan 430072 (China); Teng, Fei [Department of Physics and Astronomy, University of Utah,115 South 1400 East, Salt Lake City, UT 84112 (United States)

2017-04-07

By expanding the reduced Pfaffian in the tree level Cachazo-He-Yuan (CHY) integrands for Yang-Mills (YM) and nonlinear sigma model (NLSM), we can get the Bern-Carrasco-Johansson (BCJ) numerators in Del Duca-Dixon-Maltoni (DDM) form for arbitrary number of particles in any spacetime dimensions. In this work, we give a set of very straightforward graphic rules based on spanning trees for a direct evaluation of the BCJ numerators for YM and NLSM. Such rules can be derived from the Laplace expansion of the corresponding reduced Pfaffian. For YM, the each one of the (n−2)! DDM form BCJ numerators contains exactly (n−1)! terms, corresponding to the increasing trees with respect to the color order. For NLSM, the number of nonzero numerators is at most (n−2)!−(n−3)!, less than those of several previous constructions.

Validity of the construct of Right-Wing Authoritarianism and its measure in post-socialistic region: A case of the Czech Republic

Czech Academy of Sciences Publication Activity Database

Chylíková, Johana; Buchtík, Martin

2016-01-01

Roč. 7, č. 1 (2016) ISSN 2067-2640 R&D Projects: GA ČR GA13-10320S; GA MŠk(CZ) LM2015060 Institutional support: RVO:68378025 Keywords : authoritarianism * RWA Scale * Construct Validity Subject RIV: AO - Sociology, Demography https://docs. google .com/viewer?a=v&pid=sites&srcid=ZGVmYXVsdGRvbWFpbnxqcnNwb25lfGd4OjU3YmQ1YmM1MmVjM2RlNTc

Need jõulud on plaadiletil erilised / Immo Mihkelson

Index Scriptorium Estoniae

Mihkelson, Immo, 1959-

2002-01-01

Heliplaatidest Nana Mouskouri "Ode To Joy", "Vienna Boys Choir Goes Pop", Roxette "The Ballad Hits", "Music of the Millenium III", "Smatsh Hits 5", "Golden Slumbers. A Father's Lullaby", "Jazz Lullabies", Andrea Bocelli "Sentimento", Leonhard Cohen "The Essential"

Some case studies of geophysical exploration of archaeological sites in Yugoslavia

Science.gov (United States)

Komatina, Snezana; Timotijevic, Zoran

1999-03-01

One of the youngest branches of environmental geophysics application is the preservation of national heritage. Numerous digital techniques developed for exploration directed to urban planning can also be applied to investigations of historic buildings. In identifying near-surface layers containing objects of previous civilizations, various sophisticated geophysical methods are used. In the paper, application of geophysics in quantification of possible problems necessary to be carried out in order to get an archaeological map of some locality is discussed [Komatina, S., 1996]. Sophisticated geophysical methods in the preservation of national heritage. Proc. of Int. Conf. Architecture and Urbanism at the turn of the Millenium, Beograd, pp. 39-44. Finally, several examples of archaeogeophysical exploration at Divostin, Bedem and Kalenic monastery localities (Serbia, Yugoslavia) are presented.

Photovoltaics: Energy for the New Millenium

Science.gov (United States)

Surek, Thomas

2000-04-01

Photovoltaics (PV) is a semiconductor-based technology that directly converts sunlight to electricity. The stimulus for terrestrial PV started more than 25 years ago in response to the oil crises of the 1970s, which resulted in major government programs in the United States, Europe, Japan, and elsewhere. Ongoing concerns with the global environment, as well as the worldwide efforts to seek alternate, indigenous sources of energy, continue to drive the investment in PV research and deployment. Today, the manufacture, sale, and use of PV has become a billion-dollar industry worldwide, with nearly 200 megawatts (MW) of PV modules shipped in 1999. The twenty five years of research and development led to the discovery of new PV materials, devices, and fabrication approaches; continuing improvements in the efficiency and reliability of solar cells and modules; and lower PV module and system costs. This talk reviews the rapid progress that has occurred in PV technology from the laboratory to the marketplace, including reviews of the leading technology options, status and issues, and key industry players. New processes for fabricating PV materials and devices, and innovative PV approaches with low-cost potential are elements of an ongoing research program aimed at future advancements in PV cost and performance While major market opportunities continue to exist in the developing countries, where sizable populations are without any electricity, today's manufacturing expansions are fueled by market initiatives for grid-connected PV in residential and commercial buildings. The combinations of increased production capacities, with the attendant cost reductions as a result of economies of scale, are expected to lead to sustainable markets. A key to achieving the ultimate potential of PV is to continue to increase the sunlight-to-electricity conversion efficiencies and translate the laboratory successes to cost-competitive products. Building a robust technology base is essential to overcoming this high-risk transition. Then PV will make a globally significant contribution to our energy supply and environment.

Gender and the millenium development goals

CSIR Research Space (South Africa)

Njiro, E

2006-03-01

Full Text Available It has taken nearly half a century for the goals of poverty reduction and gender equality to achieve this prominence in mainstream policy concerns. In the process, the understanding of poverty has been transformed from the early equation with income...

Japan Report, Science and Technology.

Science.gov (United States)

1987-04-03

substances from plants Removal of fats and oils from snacks , such as potato chips Separation of chemical materials from natural resources Separation of...mechanically, and will be molded in order to make an ingot. This ingot will be worked plastically, i.e., extruded or forged with a view to variously...ym. Also to be noted, is that the extruded undulations are prone to erode polyethylene. Yamamoto: Since surface roughness of alumina is 0.04 ym or

Towards N = 2 SUSY homogeneous quantum cosmology; Einstein-Yang-Mills systems

International Nuclear Information System (INIS)

Donets, E.E.; Tentyukov, M.N.; Tsulaya, M.M.

1998-01-01

The application of N = 2 supersymmetric Quantum Mechanics for the quantization of homogeneous systems coupled with gravity is discussed. Starting with the superfield formulation of N = 2 SUSY sigma-model, Hermitian self-adjoint expressions for quantum Hamiltonians and Lagrangians for any signature of a sigma-model metric are obtained. This approach is then applied to coupled SU (2) Einstein-Yang-Mills (EYM) systems in axially-symmetric Bianchi - I,II,VIII, IX, Kantowski-Sachs and closed Friedmann-Robertson-Walker cosmological models. It is shown that all these models admit the embedding into N = 2 SUSY sigma-model with the explicit expressions for superpotentials, being direct sums of gravitational and Yang-Mills (YM) parts. In addition, YM parts of superpotentials exactly coincide with the corresponding Chern-Simons terms. The spontaneous SUSY breaking, caused by YM instantons in EYM systems is discussed in a number of examples

Evaluation of Functional Marrow Irradiation Based on Skeletal Marrow Composition Obtained Using Dual-Energy Computed Tomography

Energy Technology Data Exchange (ETDEWEB)

Magome, Taiki [Department of Radiological Sciences, Faculty of Health Sciences, Komazawa University, Tokyo (Japan); Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota (United States); Department of Radiology, The University of Tokyo Hospital, Tokyo (Japan); Froelich, Jerry [Department of Radiology, University of Minnesota, Minneapolis, Minnesota (United States); Takahashi, Yutaka [Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota (United States); Department of Radiation Oncology, Osaka University, Osaka (Japan); Arentsen, Luke [Department of Therapeutic Radiology, University of Minnesota, Minneapolis, Minnesota (United States); Holtan, Shernan; Verneris, Michael R. [Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota (United States); Brown, Keenan [Mindways Software Inc, Austin, Texas (United States); Haga, Akihiro; Nakagawa, Keiichi [Department of Radiology, The University of Tokyo Hospital, Tokyo (Japan); Holter Chakrabarty, Jennifer L. [College of Medicine, Oklahoma Health Sciences Center, Oklahoma City, Oklahoma (United States); Giebel, Sebastian [Department of Bone Marrow Transplantation, Comprehensive Cancer Center M. Curie-Sklodowska Memorial Institute, Gliwice (Poland); Wong, Jeffrey [Department of Radiation Oncology, Beckman Research Institute, City of Hope, Duarte, California (United States); Dusenbery, Kathryn [Department of Therapeutic Radiology, University of Minnesota, Minneapolis, Minnesota (United States); Storme, Guy [Department of Radiotherapy, Universitair Ziekenhuis Brussel, Brussels (Belgium); Hui, Susanta K., E-mail: shui@coh.org [Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota (United States); Department of Therapeutic Radiology, University of Minnesota, Minneapolis, Minnesota (United States); Department of Radiation Oncology, Beckman Research Institute, City of Hope, Duarte, California (United States)

2016-11-01

Purpose: To develop an imaging method to characterize and map marrow composition in the entire skeletal system, and to simulate differential targeted marrow irradiation based on marrow composition. Methods and Materials: Whole-body dual energy computed tomography (DECT) images of cadavers and leukemia patients were acquired, segmented to separate bone marrow components, namely, bone, red marrow (RM), and yellow marrow (YM). DECT-derived marrow fat fraction was validated using histology of lumbar vertebrae obtained from cadavers. The fractions of RM (RMF = RM/total marrow) and YMF were calculated in each skeletal region to assess the correlation of marrow composition with sites and ages. Treatment planning was simulated to target irradiation differentially at a higher dose (18 Gy) to either RM or YM and a lower dose (12 Gy) to the rest of the skeleton. Results: A significant correlation between fat fractions obtained from DECT and cadaver histology samples was observed (r=0.861, P<.0001, Pearson). The RMF decreased in the head, neck, and chest was significantly inversely correlated with age but did not show any significant age-related changes in the abdomen and pelvis regions. Conformity of radiation to targets (RM, YM) was significantly dependent on skeletal sites. The radiation exposure was significantly reduced (P<.05, t test) to organs at risk (OARs) in RM and YM irradiation compared with standard total marrow irradiation (TMI). Conclusions: Whole-body DECT offers a new imaging technique to visualize and measure skeletal-wide marrow composition. The DECT-based treatment planning offers volumetric and site-specific precise radiation dosimetry of RM and YM, which varies with aging. Our proposed method could be used as a functional compartment of TMI for further targeted radiation to specific bone marrow environment, dose escalation, reduction of doses to OARs, or a combination of these factors.

Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Amphotericin B

Science.gov (United States)

Hull, Claire M.; Parker, Josie E.; Bader, Oliver; Weig, Michael; Gross, Uwe; Warrilow, Andrew G. S.; Kelly, Diane E.

2012-01-01

We identified a clinical isolate of Candida glabrata (CG156) exhibiting flocculent growth and cross-resistance to fluconazole (FLC), voriconazole (VRC), and amphotericin B (AMB), with MICs of >256, >256, and 32 μg ml−1, respectively. Sterol analysis using gas chromatography-mass spectrometry (GC-MS) revealed that CG156 was a sterol 14α-demethylase (Erg11p) mutant, wherein 14α-methylated intermediates (lanosterol was >80% of the total) were the only detectable sterols. ERG11 sequencing indicated that CG156 harbored a single-amino-acid substitution (G315D) which nullified the function of native Erg11p. In heterologous expression studies using a doxycycline-regulatable Saccharomyces cerevisiae erg11 strain, wild-type C. glabrata Erg11p fully complemented the function of S. cerevisiae sterol 14α-demethylase, restoring growth and ergosterol synthesis in recombinant yeast; mutated CG156 Erg11p did not. CG156 was culturable using sterol-free, glucose-containing yeast minimal medium (glcYM). However, when grown on sterol-supplemented glcYM (with ergosta 7,22-dienol, ergosterol, cholestanol, cholesterol, Δ7-cholestenol, or desmosterol), CG156 cultures exhibited shorter lag phases, reached higher cell densities, and showed alterations in cellular sterol composition. Unlike comparator isolates (harboring wild-type ERG11) that became less sensitive to FLC and VRC when cultured on sterol-supplemented glcYM, facultative sterol uptake by CG156 did not affect its azole-resistant phenotype. Conversely, CG156 grown using glcYM with ergosterol (or with ergosta 7,22-dienol) showed increased sensitivity to AMB; CG156 grown using glcYM with cholesterol (or with cholestanol) became more resistant (MICs of 2 and >64 μg AMB ml−1, respectively). Our results provide insights into the consequences of sterol uptake and metabolism on growth and antifungal resistance in C. glabrata. PMID:22615281

Osoczowy poziom homocysteiny jako czynnik ryzyka wystąpienia złamań w przebiegu osteoporozy u ludzi w wieku podeszłym = The plasma levels of homocysteine as a risk factor for fractures in osteoporosis in the elderly

Directory of Open Access Journals (Sweden)

Izabela Mirlak

2016-05-01

  Słowa kluczowe: osteoporoza, homocysteina, menopauza, złamanie szyjki kości udowej. Keywords: osteoporosis, homocysteine, menopause, hip fracture.   Streszczenie   Wstęp. Osteoporoza jest chorobą charakteryzującą się niską masą kostną i zniszczeniami mikroarchitektury tkanki kostnej, która prowadzi do kruchości kości i zwiększa ryzyko złamań. Osteoporoza i związane z nią złamania kości mają ogromne znaczenie społeczne i gospodarcze na całym świecie. Badania sugerują, że maksymalna masa kostna i szybkość jej utraty związane ze starzeniem, są zdeterminowane przez czynniki genetyczne w podobnym stopniu jak przez czynniki środowiskowe. Kumulacja homocysteiny jest toksyczna dla układu kostnego (osteoporoza, oka (dyslokacja soczewki i centralnego układu nerwowego (drgawki, zaburzenia psychiatryczne. Wywołuje także zaburzenia układu naczyniowego (udar i inne zdarzenia sercowo naczyniowe. Cel. Wpływ poziomu homocysteiny w osoczu na ryzyko wystąpienia osteoporozy i jej powikłań. Materiały i metody. Posługując się słowami kluczowymi przeszukano zagraniczne bazy bibliograficzne: Embase, Medline, ScienceDirect, Web of Science. Przeanalizowano badania kliniczne, opublikowane w języku angielskim w międzynarodowych czasopismach. Wyniki. Zaobserwowano związek pomiędzy stężeniem homocysteiny, a utratą masy kostnej. Poziom homocysteiny w osoczu jest znacząco wyższy u kobiet z osteoporozą i odwrotnie proporcjonalny do gęstości kości kręgów lędźwiowych i szyjki kości udowej. Wnioski. Osoczowy poziom homocysteiny jest czynnikiem ryzyka wystąpienia złamań w przebiegu osteoporozy u ludzi w wieku podeszłym.   Abstract   Admission. Osteoporosis is a disease characterized by low bone mass and microarchitectural damage of bone tissue  which leads to bone fragility and increased risk of fracture. Osteoporosis and related fractures are of great social and economic importance throughout the world. Studies suggest

PAHO: Developing new partnerships and cementing old ones ...

International Development Research Centre (IDRC) Digital Library (Canada)

PAHO's involvement was natural, as the organization “has worked with The ... Sustainability and the Global Environment (SAGE) at Wisconsin University, ... when the Millenium Ecosystem Assessment was done,” said Dr Corvalan. ... Sustainable Development and Environmental Health, Pan American Health Organization.

ERMYN: Environmental Radiation Model for the Yucca Mountain, Nevada

International Nuclear Information System (INIS)

Wu, D.W.; Wasiolek, M.A.; Tappen, J.J.; Rautenstrauch, K.R.; Smith, A.J.

2002-01-01

This paper briefly describes a new biosphere model, ERMYN, that was developed to characterize biosphere processes for radionuclides released from the proposed high-level radioactive waste geologic repository at Yucca Mountain (YM). Biosphere modeling for YM is conducted independently for two radionuclide release modes and resulting exposure scenarios, groundwater release and volcanic release. This paper focuses on the model for groundwater release. The groundwater release exposure scenario addresses the case in which the geosphere-biosphere interface is well extraction of contaminated groundwater

ERMYN: Environmental Radiation Model for the Yucca Mountain, Nevada

Energy Technology Data Exchange (ETDEWEB)

D.W. Wu; M.A. Wasiolek; J.J. Tappen; K.R. Rautenstrauch; A.J. Smith

2002-11-18

This paper briefly describes a new biosphere model, ERMYN, that was developed to characterize biosphere processes for radionuclides released from the proposed high-level radioactive waste geologic repository at Yucca Mountain (YM). Biosphere modeling for YM is conducted independently for two radionuclide release modes and resulting exposure scenarios, groundwater release and volcanic release. This paper focuses on the model for groundwater release. The groundwater release exposure scenario addresses the case in which the geosphere-biosphere interface is well extraction of contaminated groundwater.

Intersection of separatrices of periodical trajectories and non-integrability of the classical Yang-Mills equations

International Nuclear Information System (INIS)

Nikolaevskij, E.S.; Shchur, L.N.

1983-01-01

A perticular case of the Yang-Mills (YM) equations has been studied. For this system a transversal intersection of separatrices of unstable periodical trajectories is discovered, hence, it follows that there are no first real-analytical integrals of motion additional to the Hamiltonian. As a result, a complete set of integrals does not exist for the system describing the classical YM fields. Numerical methods of constructing separatrices, double-asymptotical solutions and of determining the angles between separatrices have been described

Global Journal of Social Sciences - Vol 2, No 1 (2003)

African Journals Online (AJOL)

Youth unemployment in Nigeria: some implications for the third Millenium · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. O. O. Alanana, 21-26. http://dx.doi.org/10.4314/gjss.v2i1.22763 ...

Global hindcasts and future projections of coastal nitrogen and phosphorus loads due to shellfish and seaweed aquaculture

NARCIS (Netherlands)

Bouwman, A.F.; Pawlowski, M.; Liu, C.; Beusen, A.H.W.; Shumway, S.E.; Glibert, P.M.; Overbeek, C.C.

2011-01-01

A model was developed to estimate nitrogen and phosphorus budgets for aquaculture production of crustaceans, bivalves, gastropods, and seaweed, using country production data for the 1970–2006 period from the Food and Agriculture Organization and scenarios based on the Millenium Assessment for

The Indian Ocean: A perspective

Digital Repository Service at National Institute of Oceanography (India)

. These chapters contain research results almost upto the end of the second millenium. This book is aimed to be a handy source of data and information to teachers, graduate and post-graduate students and research scientists. This book would be useful for policy...

Fulltext PDF

Indian Academy of Sciences (India)

91. SERIES ARTICLES. 8 Eledronlc Commerce. Cash Transactions. V Raiaraman. GENERAL ARTICLES. 15 Mlcroscale Experiments In Chemistry - The Need of the New Millenium. 52. Physical Chemistry Experiments on Microscale. Shriniwas lKelkar, Dilip D Dhavale and JeevanGChandwadkar. 22 Quadrupole Ion Traps.

Zero-modes of non-Abelian solitons in three-dimensional gauge theories

International Nuclear Information System (INIS)

Eto, Minoru; Gudnason, Sven Bjarke

2011-01-01

We study non-Abelian solitons of the Bogomol'nyi type in N=2 (d = 2 + 1) supersymmetric Chern-Simons (CS) and Yang-Mills (YM) theory with a generic gauge group. In CS theory, we find topological, non-topological and semi-local (non-)topological vortices of non-Abelian kinds in unbroken, broken and partially broken vacua. We calculate the number of zero-modes using an index theorem and then we apply the moduli matrix formalism to realize the moduli parameters. For the topological solitons we exhaust all the moduli while we study several examples of the non-topological and semi-local solitons. We find that the zero-modes of the topological solitons are governed by the moduli matrix H 0 only and those of the non-topological solitons are governed by both H 0 and the gauge invariant field Ω. We prove local uniqueness of the master equation in the YM case and finally compare all results between the CS and YM theories.

Assessing microbiologically induced corrosion of waste package materials in the Yucca Mountain repository

Energy Technology Data Exchange (ETDEWEB)

Horn, J. M., LLNL

1998-01-01

The contribution of bacterial activities to corrosion of nuclear waste package materials must be determined to predict the adequacy of containment for a potential nuclear waste repository at Yucca Mountain (YM), NV. The program to evaluate potential microbially induced corrosion (MIC) of candidate waste container materials includes characterization of bacteria in the post-construction YM environment, determination of their required growth conditions and growth rates, quantitative assessment of the biochemical contribution to metal corrosion, and evaluation of overall MIC rates on candidate waste package materials.

to view fulltext PDF

Indian Academy of Sciences (India)

6 Mlcroscale Experiments In Chemistry - The Need of the New Millenium. Organic Qualitative Analysis and Mixture Separation on. Microscale. Shriniwas l Kelkar and Dilip D Dhavale. GENERAL ARTICLES. 13 Global Warming: A Myth? 22. 29. Credibility of Climate Scenarios Predicted by Systems. Simulations. Deepanjan ...

Global Hindcasts and Future Projections of Coastal Nitrogen and Phosphorus Loads Due to Shellfish and Seaweed Aquaculture

NARCIS (Netherlands)

Bouwman, A.F.; Pawlowski, M.; Liu, C.; Beusen, A.W.H.; Shumway, S.E.; Glibert, P.M.; Overbeek, C.C.

2011-01-01

A model was developed to estimate nitrogen and phosphorus budgets for aquaculture production of crustaceans, bivalves, gastropods, and seaweed, using country production data for the 1970–2006 period from the Food and Agriculture Organi- zation and scenarios based on the Millenium Assessment for

Interests versus morality in politics

Directory of Open Access Journals (Sweden)

Radojčić Mirjana S.

2002-01-01

Full Text Available In this individual project the relationship between interests and moral in politics will be considered, taking into consideration the disintegration of former Yugoslavia and the processes of globalization. The starting thesis of the research is that the main actors of global politics are still guided by the modern principles of real-politics with interests as its basic category and power as its supreme value. In that context the main elements of external politics of USA as the key actor of the processes will be specially considered. In the concluding part of the research author will be argue in favor of the affirmation of a new model of global politics, matching the character and scope of the problems faced by humanity at the turn of the century and the millenium.

Preliminary Evaluation of the Effects of Buried Volcanoes on Estimates of Volcano Probability for the Proposed Repository Site at Yucca Mountain, Nevada

Science.gov (United States)

Hill, B. E.; La Femina, P. C.; Stamatakos, J.; Connor, C. B.

2002-12-01

Probability models that calculate the likelihood of new volcano formation in the Yucca Mountain (YM) area depend on the timing and location of past volcanic activity. Previous spatio-temporal patterns indicated a 10-4 to 10-3 probability of volcanic disruption of the proposed radioactive waste repository site at YM during the 10,000 year post-closure performance period (Connor et al. 2000, JGR 105:1). A recent aeromagnetic survey (Blakely et al. 2000, USGS OFR 00-188), however, identified up to 20 anomalies in alluvium-filled basins, which have characteristics indicative of buried basalt (O'Leary et al. 2002, USGS OFR 02-020). Independent evaluation of these data, combined with new ground magnetic surveys, shows that these anomalies may represent at least ten additional buried basaltic volcanoes, which have not been included in previous probability calculations. This interpretation, if true, nearly doubles the number of basaltic volcanoes within 30 km [19 mi] of YM. Moreover, the magnetic signature of about half of the recognized basaltic volcanoes in the YM area cannot be readily identified in areas where bedrock also produces large amplitude magnetic anomalies, suggesting that additional volcanoes may be present but undetected in the YM area. In the absence of direct age information, we evaluate the potential effects of alternative age assumptions on spatio-temporal probability models. Interpreted burial depths of >50 m [164 ft] suggest ages >2 Ma, based on sedimentation rates typical for these alluvial basins (Stamatakos et al., 1997, J. Geol. 105). Defining volcanic events as individual points, previous probability models generally used recurrence rates of 2-5 volcanoes/million years (v/Myr). If the identified anomalies are buried volcanoes that are all >5 Ma or uniformly distributed between 2-10 Ma, calculated probabilities of future volcanic disruption at YM change by <30%. However, a uniform age distribution between 2-5 Ma for the presumed buried volcanoes

OCRWM Science and Technology Program Cementitious Materials Technologies

International Nuclear Information System (INIS)

DOE

2004-01-01

This potential project will develop and test cost effective cementitious materials for construction of Yucca Mountain (YM) inverts, drift liners, and bulkheads. These high silica cementitious materials will be designed to buffer the pH and Eh of the groundwater, to slow corrosion of waste packages (WP), and to retard radionuclide migration. While being compatible with YM repository systems, these materials are expected to be less expensive to produce, and as strong, and more durable than ordinary Portland Cement (OPC). Therefore, building out the repository with these cementitious materials may significantly reduce these costs and reduce uncertainty in short-( 10,000 yr) repository performance. Both laboratory development and natural analog studies are anticipated using a unique combination of expertise at ORNL, UT, UC Berkeley, and Minatom to develop and test high-silica hydraulic, cementitious binders for use at YM. The major tasks of this project are to (1) formulate and make candidate cementitious materials using high-silica hydraulic hinders, (2) measure the physical and chemical properties of these materials, (3) expose combinations of these materials and WP materials to static and flowing YM groundwater at temperatures consistent with the expected repository conditions, (4) examine specimens of both the cementitious materials and WP materials periodically for chemical and mineralogical changes to determine reaction mechanisms and kinetics, and (5) predict the long-term performance of the material by thermodynamic and transport modeling and by comparisons with natural analogs

Intrinsic nonadiabatic topological torque in magnetic skyrmions and vortices

KAUST Repository

Akosa, Collins Ashu; Ndiaye, Papa Birame; Manchon, Aurelien

2017-01-01

We propose that topological spin currents flowing in topologically nontrivial magnetic textures, such as magnetic skyrmions and vortices, produce an intrinsic nonadiabatic torque of the form Tt∼[(∂xm×∂ym)·m]∂ym. We show that this torque, which is absent in one-dimensional domain walls and/or nontopological textures, is responsible for the enhanced nonadiabaticity parameter observed in magnetic vortices compared to one-dimensional textures. The impact of this torque on the motion of magnetic skyrmions is expected to be crucial, especially to determine their robustness against defects and pinning centers.

Intrinsic nonadiabatic topological torque in magnetic skyrmions and vortices

KAUST Repository

Akosa, Collins Ashu

2017-03-01

We propose that topological spin currents flowing in topologically nontrivial magnetic textures, such as magnetic skyrmions and vortices, produce an intrinsic nonadiabatic torque of the form Tt∼[(∂xm×∂ym)·m]∂ym. We show that this torque, which is absent in one-dimensional domain walls and/or nontopological textures, is responsible for the enhanced nonadiabaticity parameter observed in magnetic vortices compared to one-dimensional textures. The impact of this torque on the motion of magnetic skyrmions is expected to be crucial, especially to determine their robustness against defects and pinning centers.

Resonance – Journal of Science Education | News

Indian Academy of Sciences (India)

Electronic Commerce-Cash Transactions · V Rajaraman · More Details Fulltext PDF. pp 15-21 Series Article. Microscale Experiments in Chemistry: The Need of the New Millenium-Physical Chemistry Experiments on Microscale · Shriniwas L Kelkar Dilip D Dhavale Jeevan G Chandwadkar · More Details Fulltext PDF.

PAHO: Developing new partnerships and cementing old ones ...

International Development Research Centre (IDRC) Digital Library (Canada)

2011-05-09

May 9, 2011 ... Initiated in 2001, the Millenium Ecosystem Assessment monitored the consequences of ecosystem change for human welfare. Ecohealth is “an emerging area in public health: everything is related to changes in the environment.” Carlos Corvalan Sustainable Development and Environmental Health, Pan ...

Management of severe malnutrition | Schubl | South African Journal ...

African Journals Online (AJOL)

In summary, if the Millenium Development Goals (MDGs) are to be addressed effectively, it is imperative that severe malnutrition be addressed at the international and national level, using strategies that work, and that additional resources are committed to improving hospital treatment and establishing community-based ...

Resonance – Journal of Science Education | News

Indian Academy of Sciences (India)

Electronic Commerce - Payment Schemes · V Rajaraman · More Details Fulltext PDF. pp 14-22 Series Article. Microscale Experiments in Chemistry – The Need of the New Millenium-Microscale Inorganic Qualitative Analysis and New Methods of Titrations for Introduction at All Levels in Chemistry Laboratories · Shriniwas L ...

Microscale Experiments in Chemistry–The Need of the New ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 7. Microscale Experiments in Chemistry – The Need of the New Millenium - Organic Qualitative Analysis and Mixture Separation on Microscale. Shriniwas L Kelkar Dilip D Dhavale. Series Article Volume 6 Issue 7 July 2001 pp 6-12 ...

The human right to water and sanitation: reflections on making the system effective

NARCIS (Netherlands)

Obani, P.; Gupta, J.; Bhaduri, A.; Bogardi, J.; Leentvaar, J.; Marx, S.

2014-01-01

The Millenium Development Goal (MDG) on water has been more successful than the MDG on sanitation. Does this have implications for the human right to sanitation? This chapter argues that there are key differences between access to water and sanitation in terms of the legal content of both, the

Carbon 14, carbon 13 and oxygen 18 in carbonate sediments from lake Titicaca. Preliminary estimates of sedimentation rate and paleoclimatological attempt

International Nuclear Information System (INIS)

Fontes, J.-C.; Boulange, Bruno; Rodrigo, L.-A.

1981-01-01

Stable isotope and radiocarbon measurements in carbonates from Titicaca lake indicate equilibrium with lake water and atmospheric CO 2 . Average sedimentation rate is close to 0,5 mm.yr -1 for the last millenium which was marked by large fluctuations of the hydrologic balance and lake level [fr

Carbon 14, carbon 13 and oxygen 18 in carbonate sediments from Lake Titicaca. Preliminary estimates of sedimentation rate and paleoclimatological attempt

Energy Technology Data Exchange (ETDEWEB)

Fontes, J.C. (Paris-11 Univ., 91 - Orsay (France)); Boulange, B. (Orstom, 75 - Paris (France)); Rodrigo, L.A. (Universidad Mayor de San Andres, La Paz (Bolivia). Lab. de Fisica Cosmica de Chacaltaya)

1981-07-06

Stable isotope and radiocarbon measurements in carbonates from Lake Titicaca indicate equilibrium with lake water and atmospheric CO/sub 2/. Average sedimentation rate is close to 0,5 mm.yr/sup -1/ for the last millenium which was marked by large fluctuations of the hydrologic balance and lake level.

The role of poverty reduction strategies in achieving the millennium development goals

NARCIS (Netherlands)

Bezemer, Dirk; Eggen, Andrea

2008-01-01

We provide a literature overview of the linkages between Poverty Reduction Strategy Papers (PRSPs) and the Millenium Development Goals (MDGs) and use novel data to examine their relation. We find that introduction of a PRSP is associated with progress in four of the nine MDG indicators we study.

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 4. Microscale Experiments in Chemistry: The Need of the New Millenium-Physical Chemistry Experiments on Microscale. Shriniwas L Kelkar Dilip D Dhavale Jeevan G Chandwadkar. Series Article Volume 6 Issue 4 April 2001 pp 15-21 ...

On maximally supersymmetric Yang-Mills theories

International Nuclear Information System (INIS)

Movshev, M.; Schwarz, A.

2004-01-01

We consider ten-dimensional supersymmetric Yang-Mills theory (10D SUSY YM theory) and its dimensional reductions, in particular, BFSS and IKKT models. We formulate these theories using algebraic techniques based on application of differential graded Lie algebras and associative algebras as well as of more general objects, L ∞ - and A ∞ -algebras. We show that using pure spinor formulation of 10D SUSY YM theory equations of motion and isotwistor formalism one can interpret these equations as Maurer-Cartan equations for some differential Lie algebra. This statement can be used to write BV action functional of 10D SUSY YM theory in Chern-Simons form. The differential Lie algebra we constructed is closely related to differential associative algebra (Ω,∂) of (0,k)-forms on some supermanifold; the Lie algebra is tensor product of (Ω,) and matrix algebra. We construct several other algebras that are quasiisomorphic to (Ω,∂) and, therefore, also can be used to give BV formulation of 10D SUSY YM theory and its reductions. In particular, (Ω,∂) is quasiisomorphic to the algebra (B,d), constructed by Berkovits. The algebras (Ω 0 ,∂) and (B 0 ,d) obtained from (Ω,∂) and (B,d) by means of reduction to a point can be used to give a BV-formulation of IKKT model. We introduce associative algebra SYM as algebra where relations are defined as equations of motion of IKKT model and show that Koszul dual to the algebra (B 0 ,d) is quasiisomorphic to SYM

Effects of an anti-oxidative ACAT inhibitor on apoptosis/necrosis and cholesterol accumulation under oxidative stress in THP-1 cell-derived foam cells.

Science.gov (United States)

Miike, Tomohiro; Shirahase, Hiroaki; Jino, Hiroshi; Kunishiro, Kazuyoshi; Kanda, Mamoru; Kurahashi, Kazuyoshi

2008-01-02

THP-1 cell-derived foam cells were exposed to oxidative stress through combined treatment with acetylated LDL (acLDL) and copper ions (Cu2+). The foam cells showed caspase-dependent apoptotic changes on exposure to oxidative stress for 6 h, and necrotic changes with the leakage of LDH after 24 h. KY-455, an anti-oxidative ACAT inhibitor, and ascorbic acid (VC) but not YM-750, an ACAT inhibitor, prevented apoptotic and necrotic changes. These preventive effects of KY-455 and VC were accompanied by the inhibition of lipid peroxidation in culture medium containing acLDL and Cu2+, suggesting the involvement of oxidized acLDL in apoptosis and necrosis. Foam cells accumulated esterified cholesterol (EC) for 24 h in the presence of acLDL without Cu2+, which was suppressed by KY-455 and YM-750. Foam cells showed necrotic changes and died in the presence of acLDL and Cu2+. KY-455 but not YM-750 prevented cell death and reduced the amount of EC accumulated. The foam cells treated with VC further accumulated EC without necrotic changes for 24 h even in the presence of acLDL and Cu2+. YM-750 as well as KY-455 inhibited lipid accumulation when co-incubated with VC in foam cells exposed to oxidative stress. It is concluded that an anti-oxidative ACAT inhibitor or the combination of an antioxidant and an ACAT inhibitor protects foam cells from oxidative stress and effectively reduces cholesterol levels, which would be a promising approach in anti-atherosclerotic therapy.

FRG-1: new millenium - new compact core

International Nuclear Information System (INIS)

Schreiner, P.; Knop, W.

2001-01-01

The GKSS research center Geesthacht GmbH operates the MTR-type swimming pool research reactor FRG-1 (5 MW) for more than 40 years. The FRG-1 has been converted in February 1991 from HEU (93 %) to LEU (20 %) in one step and at that time the core size was reduced from 49 to 26 fuel elements. Consequently the thermal neutron flux in beam tube positions could be increased by more than a factor of two. It is the strong intention of GKSS to continue the operation of the FRG-1 research reactor for at least an additional 15 years with high availability and utilization. The reactor has been operated during the last years for approximately 250 full power days per year. To prepare the FRG-1 for an efficient future use, the core size has been reduced in a second step from 26 fuel elements to 12 fuel elements. (author)

An industrial mineral for the next millenium

Directory of Open Access Journals (Sweden)

Čorej Peter

2001-12-01

Full Text Available Talc is a mineral of high quality and from chemical point of view it is Mg3Si04010 /OH/2. It usually contains different additional minerals that signigicantly affect its color and most of all its quality. The quality is decreased by the existence of Fe3+, pyrite and oxide Mn. Talc is used mainly in the paper manufacturing, cosmetic industry, glass industry, as a chemical catalyzator, ingredient in making explosives, in pharmaceutics and car industry.Some of the biggest producers of talc are: China - 2.35 mills tons/year, the USA - 1.0 mills tons/year, India - 500.00 kt/year, Finland - 425 kt/year, and Brazil with 325 kt/year. The most important deposits are located in: Finland (Sotkano deposit, in the USA (deposits in the state of New York, Virginia and Vermont in Canada (province of Ontariou, Australia (Three Springs deposit etc.Among one of the first companies being interested in this deposit of talc (along with the Rima Muran Ltd were companies from Germany – Gebruder Dorfner and Thyssen Schachtbau. The result of the detailed research of the deposit performed in 1994 was a Feasibility Study. This deposit with 28 milions tons of talc belongs to the group of most important deposits in the world.Initial acivities began in September 2000 and they are still in progress.The first ton will be placed into themarket during this year. The deposit lies about 350 meters beneath the earth surface. The whole body of talc is 2700 meters from West-East and 820 meters from North-South. The average depth of the deposit is 200 meters.

Human resources management and millenium development goal ...

African Journals Online (AJOL)

Sophia: An African Journal of Philosophy. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 10, No 2 (2008) >. Log in or Register to get access to full text downloads.

Browse Title Index

African Journals Online (AJOL)

Items 201 - 220 of 220 ... Vol 10, No 1&2 (2011), Youth unemployment and its consequences in Calabar metropolis: Need for government intervention, Abstract PDF. GA Ugal, EN Nwagbara, FA Uyang. Vol 2, No 1 (2003), Youth unemployment in Nigeria: some implications for the third Millenium, Abstract PDF. O. O. Alanana.

SERIES ARTICLES

Indian Academy of Sciences (India)

Microscale Experiments in Chemistry - The Need of the New Millenium. Experiments Which Bring Theory Closer to Laboratories. Shriniwas L Kelkar and Dilip D Dhavale. GENERAL ARTICLES. Chandra's X-ray Vision. K P Singh. Space-Filling Curves. R C Mittal. DNA Chip. The Whats, the Whys and the Hows. Bhismadev ...

Resonance – Journal of Science Education | News

Indian Academy of Sciences (India)

pp 6-12 Series Article. Microscale Experiments in Chemistry – The Need of the New Millenium - Organic Qualitative Analysis and Mixture Separation on Microscale · Shriniwas L Kelkar Dilip D Dhavale · More Details Fulltext PDF. pp 13-21 General Article. Global Warming: A Myth? - Credibility of Climate Scenarios Predicted ...

Gender Equality in Education in the Context of the Millennium Development Goals: Challenges and Opportunities for Women

Science.gov (United States)

Moletsane, Relebohile

2005-01-01

This article addresses the question: In the context of poverty, gender-based violence (GBV) and HIV/AIDS currently ravaging under-resourced countries, dare we set our hopes for gender- equitable development in general, and gender equality in education in particular, on the Millenium Development Goals MDGs? The article analyses the…

Youth unemployment in Nigeria: some implications for the third ...

African Journals Online (AJOL)

Youth unemployment in Nigeria: some implications for the third Millenium. ... Government in league with the private sector it is further suggested, can create job corps for school dropouts as one major remedy to unemployment. The paper further sees hope for Nigeria only if Youths are mobilized by way of genuinely ...

A gluon cluster solution of effective Yang-Mills theory

CERN Document Server

Pavlovsky, O V

2001-01-01

A classical solution of the effective Yang-Mills (YM) theory with a finite energy and nonstandard Lagrangian was obtained. Influence of vacuum polarization on gluon cluster formation was discussed. Appearance of cluster solutions in the theory of non-Abelian fields can take place only if the result goes beyond the framework of pure YM theory. It is shown that account of quantum effects of polarized vacuum in the presence of a classical gluon field can also result in formation of the solutions. Solutions with the finite intrinsic energy are provided. Besides, fields of colour groups SU(2) were studied

Avances en los Objetivos de Desarrollo del Milenio 4 y 5 en Mesoamérica Progress on the Millenium Development Goals 4 and 5 in Mesoamerica

Directory of Open Access Journals (Sweden)

Rafael Lozano

2011-01-01

Full Text Available OBJETIVOS: Presentar los avances realizados en la región mesoamericana en relación con los Objetivos de Desarrollo del Milenio 4 y 5 por medio de su análisis y discutir las intervenciones más relevantes para ayudar en el logro de estos objetivos o, por lo menos, en mantener su trayectoria. MATERIAL Y MÉTODOS: Se utilizaron como fuentes las estimaciones de 1990-2008 sobre mortalidad en menores de cinco años y materna, las coberturas de vacunación contra difteria, tétanos y tosferina (DTP, atención prenatal y atención del parto por personal calificado, realizadas por el Instituto de la Métrica y Evaluación en Salud y las causas de mortalidad en menores de cinco años, realizadas por el Grupo de Referencia sobre Epidemiología y Salud en la Infancia de la OMS (CHERG. RESULTADOS: La tendencia de la tasa de mortalidad de menores de cinco años (ODM-4 muestra una reducción anual de 4.2% en los últimos 18 años, comparada con la reducción global de 2.1%. En contraste, la tasa de descenso de la mortalidad materna (ODM-5 es muy heterogénea y ninguno de los países de la región alcanzará este objetivo. CONCLUSIÓN: Los esfuerzos realizados por los países en Mesoamérica han sido sustantivos en la reducción de mortalidad en menores de cinco años; sin embargo no han sido suficientes para alcanzar la meta programada por el ODM-5. Aunque la tendencia es correcta, el ritmo de descenso cumplirá parcialmente con los compromisos adquiridos para erradicar la pobreza.OBJECTIVES: To describe the advances made by countries in the Mesoamerican region towards reaching Millenium Development Goals (MDG 4 and 5, and discuss the most useful tasks to help the region in accomplishing or keeping track of these objectives. MATERIAL AND METHODS: The trend estimates of maternal and under 5 mortality from 1990 to 2008, the effective coverage of vaccination against diphteria, pertussis and tetanus (DPT, prenatal care and childbirth by qualified personnel were

Pop / Koit Raudsepp

Index Scriptorium Estoniae

Raudsepp, Koit

2003-01-01

Heliplaatidest: Yeah Yeah Yeahs "Fever To Tell", Placebo "Sleeping With Ghosts", Sixpence None The Richer "Divine Discontent", Martin L.Gore "Counterfeit2" MJ Cole "Cut tothe Chase", Toktok Vs. Soffy O. "Toktok Vs Soffy O.", W.I.T. "Whatever It Takes", Holger Czukay & U-She "The New Millenium", The Fugees "Greatest Hits"

Use of Dehydrated Agar to Estimate Microbial Water Quality for Horticulture Irrigation.

Science.gov (United States)

Meador, Dustin P; Fisher, Paul R; Guy, Charles L; Harmon, Philip F; Peres, Natalia A; Teplitski, Max

2016-07-01

Petrifilms are dehydrated agar culture plates that have been used to quantify colony forming units (CFU) mL of either aerobic bacteria (Petrifilm-AC) or fungus (Petrifilm-YM), depending on substrate composition. Microbes in irrigation systems can indicate biofilm risk and potential clogging of irrigation emitters. The research objective was to compare counts on Petrifilms versus traditional, hydrated-agar plates using samples collected from recirculated irrigation waters and cultures of isolated known species. The estimated count (in CFU mL) from a recirculated irrigation sample after 7 d of incubation on Petrifilm-YM was only 5.5% of the count quantified using sabouraud dextrose agar (SDA) with chloramphenicol after 14 d. In a separate experiment with a known species, Petrifilm-YM did not successfully culture zoospores of . Isolates of viable zoospores were cultured successfully on potato-dextrose agar (PDA), with comparable counts with a vegetable juice medium supplemented with the antibiotics pimaricin, ampicillin, rifamycin, pentochloronitrobenzene and hymexazol (PARP-H). The quantification of pv. Begoniaceae on Petrifilm-AC was not significantly different ( < 0.05) than on PDA, but was lower than on Reasoner and Goldrich agar (R2A) or with a hemocytometer. The current formulation of Petrifilm-YM is unlikely to be a useful monitoring method for plant pathogens in irrigation water because of the inability to successfully culture oomycetes. However, Petrifilm-AC was an effective method to quantify bacteria and can provide an easy-to-use on-farm tool to monitor biofilm risk and microbial density. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

Targeting survivin as a potential new treatment for chondrosarcoma of bone

Science.gov (United States)

de Jong, Y; van Oosterwijk, J G; Kruisselbrink, A B; Briaire-de Bruijn, I H; Agrogiannis, G; Baranski, Z; Cleven, A H G; Cleton-Jansen, A-M; van de Water, B; Danen, E H J; Bovée, J V M G

2016-01-01

Chondrosarcomas are malignant cartilage-forming bone tumors, which are intrinsically resistant to chemo- and radiotherapy, leaving surgical removal as the only curative treatment option. Therefore, our aim was to identify genes involved in chondrosarcoma cell survival that could serve as a target for therapy. siRNA screening for 51 apoptosis-related genes in JJ012 chondrosarcoma cells identified BIRC5, encoding survivin, as essential for chondrosarcoma survival. Using immunohistochemistry, nuclear as well as cytoplasmic survivin expression was analyzed in 207 chondrosarcomas of different subtypes. Nuclear survivin has been implicated in cell-cycle regulation while cytoplasmic localization is important for its anti-apoptotic function. RT–PCR was performed to determine expression of the most common survivin isoforms. Sensitivity to YM155, a survivin inhibitor currently in phase I/II clinical trial for other tumors, was examined in 10 chondrosarcoma cell lines using viability assay, apoptosis assay and cell-cycle analysis. Survivin expression was found in all chondrosarcoma patient samples. Higher expression of nuclear and cytoplasmic survivin was observed with increasing histological grade in central chondrosarcomas. Inhibition of survivin using YM155 showed that especially TP53 mutant cell lines were sensitive, but no caspase 3/7 or PARP cleavage was observed. Rather, YM155 treatment resulted in a block in S phase in two out of three chondrosarcoma cell lines, indicating that survivin is more involved in cell-cycle regulation than in apoptosis. Thus, survivin is important for chondrosarcoma survival and chondrosarcoma patients might benefit from survivin inhibition using YM155, for which TP53 mutational status can serve as a predictive biomarker. PMID:27159675

Concept for Underground Disposal of Nuclear Waste

Science.gov (United States)

Bowyer, J. M.

1987-01-01

Packaged waste placed in empty oil-shale mines. Concept for disposal of nuclear waste economically synergistic with earlier proposal concerning backfilling of oil-shale mines. New disposal concept superior to earlier schemes for disposal in hard-rock and salt mines because less uncertainty about ability of oil-shale mine to contain waste safely for millenium.

First-principles calculation of the elastic constants, the electronic density of states and the ductility mechanism of the intermetallic compounds: YAg, YCu and YRh

Energy Technology Data Exchange (ETDEWEB)

Wu Yurong [College of Electromechanical Engineering, Hunan University of Science and Technology, Xiantang 411201 (China); Hu Wangyu [Department of Applied Physics, Hunan University, Changsha 410082 (China)], E-mail: wangyuhu2001cn@yahoo.com.cn; Han Shaochang [Department of Applied Physics, Hunan University, Changsha 410082 (China)

2008-10-01

First-principles calculations have been used to study the elastic and electronic properties of ductility rare-earth alloy YM (M=Ag, Cu, Rh) systems. The ductility mechanism for these alloys is studied from microscopic aspect, via electronic density of states (DOS). The Fermi energy lies near a local minimum, and the hybridization is stronger than that of the common NiAl alloy, demonstrating that the ductility of these alloys is much better than that of NiAl alloy. Elastic modulus, namely, shear modulus C'=(C{sub 11}-C{sub 12})/2, bulk modulus B and C{sub 44} are calculated by volume-conserving orthorhombic, hydrostatic pressure and tri-axial shear strain, respectively. Moreover, lattice parameters, antiphase boundary (APB) energies and unstable stacking fault energies of these alloys are also studied. The APB energies are greater than the unstable stacking fault energies for these alloy systems, and this is a characteristic of the ductility rare-earth alloy. The APB energies of YRh are the highest ones in these three YM alloys, which make dislocation dissociation difficult. The DOS and APB energy results show that the ductility of YRh may be worst in these three YM systems.

First-principles calculation of the elastic constants, the electronic density of states and the ductility mechanism of the intermetallic compounds: YAg, YCu and YRh

International Nuclear Information System (INIS)

Wu Yurong; Hu Wangyu; Han Shaochang

2008-01-01

First-principles calculations have been used to study the elastic and electronic properties of ductility rare-earth alloy YM (M=Ag, Cu, Rh) systems. The ductility mechanism for these alloys is studied from microscopic aspect, via electronic density of states (DOS). The Fermi energy lies near a local minimum, and the hybridization is stronger than that of the common NiAl alloy, demonstrating that the ductility of these alloys is much better than that of NiAl alloy. Elastic modulus, namely, shear modulus C'=(C 11 -C 12 )/2, bulk modulus B and C 44 are calculated by volume-conserving orthorhombic, hydrostatic pressure and tri-axial shear strain, respectively. Moreover, lattice parameters, antiphase boundary (APB) energies and unstable stacking fault energies of these alloys are also studied. The APB energies are greater than the unstable stacking fault energies for these alloy systems, and this is a characteristic of the ductility rare-earth alloy. The APB energies of YRh are the highest ones in these three YM alloys, which make dislocation dissociation difficult. The DOS and APB energy results show that the ductility of YRh may be worst in these three YM systems

Editorial

Directory of Open Access Journals (Sweden)

Maria de Jesus Fonseca

2016-02-01

Full Text Available Millenium registou, e disso se deu conta nos Editoriais dos números 32 e 33, os seus 10 anos de existência, de 1996 a 2006, como publicação periódica sistemática. No último número, o artigo “10 Anos de MILLENIUM” também realçava o 10º aniversário da revista.  Registamos agora, neste N.º 34, os seus 10 anos de vida como publicação on-line. De facto, em Abril de 1998, são, pela primeira vez, disponibilizados on-line, em www.ipv.pt/millenium, artigos do seu N.º 4, datado de Abril de 1996 e, de seguida, disponibilizados, também on-line, artigos dos números anteriores, N.º 1, N.º 2 e N.º 3. O primeiro número completo e na íntegra posto à disposição on-line foi o N.º 6, de Março de 1997.

Initial studies to assess microbial impacts on nuclear waste disposal

International Nuclear Information System (INIS)

Horn, J.M.; Meike, A.; McCright, R.D.; Economides, B.

1996-01-01

The impacts of the native and introduced bacteria on the performance of geologic nuclear waste disposal facilities should be evaluated because these bacteria could promote corrosion of repository components and alteration of chemical and hydrological properties of the surrounding engineered and rock barriers. As a first step towards investigating these potentialities, native and introduced bacteria obtained from post-construction Yucca Mountain (YM) rock were isolated under varying conditions, including elevated temperature, low nutrient availability, and the absence of available oxygen. Individual isolates are being screened for activities associated with microbially induced corrosion of metals (MIC). Preliminary determination of growth rates of whole YM microbial communities under varying conditions was also undertaken

Author Details

African Journals Online (AJOL)

Alanana, O. O.. Vol 2, No 1 (2003) - Articles Youth unemployment in Nigeria: some implications for the third Millenium Abstract PDF. ISSN: 1596-6216. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

Libraries in West Malaysia and Singapore; A Short History.

Science.gov (United States)

Tee, Edward Lim Huck

An attempt is made to trace the history of every major library in Malay and Singapore. Social and recreational club libraries are not included, and school libraries are not extensively covered. Although it is possible to trace the history of Malaysia's libraries back to the first millenium of the Christian era, there are few written records…

[Effects of Meek skin grafting on patients with extensive deep burn at different age groups].

Science.gov (United States)

Di, H P; Niu, X H; Li, Q; Li, X L; Xue, J D; Cao, D Y; Han, D W; Xia, C D

2017-03-20

Objective: To investigate the effect of Meek skin grafting on patients with extensive deep burn at different age groups. Methods: Eighty-four patients with extensive deep burns conforming to the study criteria were hospitalized in our unit from April 2011 to April 2015. Patients were divided into children group (C, with age less than 12 years old), young and middle-aged group (YM, with age more than 18 years and less than 50 years old), and old age group (O, with age more than 55 years old) according to age, with 28 patients in each group. All patients received Meek skin grafting treatment. The use of autologous skin area, operation time, wound healing time, and hospitalization time were recorded. The survival rate of skin graft on post operation day 7, complete wound healing rate in post treatment week 2, and the mortality were calculated. Data were processed with one-way analysis of variance, t test, and χ (2) test. Results: The use of autologous skin area of patients in group C was (5.1±1.0)% total body surface area (TBSA), significantly less than (8.3±1.0)%TBSA and (8.3±1.4)%TBSA in groups YM and O, respectively (with t values 32.900 and 52.624, respectively, P values below 0.05). The operation time, wound healing time, and hospitalization time of patients in group C were (1.368±0.562) h, (9.6±0.6) and (32±11) d, significantly shorter than those in group YM [(3.235±0.011) h, (16.9±2.6) and (48±12) d, respectively] and group O [(3.692±0.481) h, (17.3±2.6) and (46±13) d, respectively, with t values from 4.350 to 21.160, P values below 0.05]. The survival rate of skin graft of patients on post operation day 7 in group C was (92±15)%, significantly higher than (81±10)% and (72±12)% in groups YM and O, respectively (with t values 5.509 and 3.229, respectively, P values below 0.05). The above indexes in groups YM and O were similar (with t values from 0.576 to 22.958, P values above 0.05). Complete wound healing rate in post treatment week 2 and the

The iota(1440) and QCD ward identities

International Nuclear Information System (INIS)

Williams, P.G.

1987-01-01

Anomalous Ward identities for QCD are analyzed with contributions of all known pseudoscalar mesons, including the glueball candidate iota(1440). Implications for the standard resolution of the U/sub A/(1) problem are examined by imposing the important and crucial constraint of positivity for the topological susceptibility chi/sub t/. The pure Yang-Mills susceptibility chi/sub t//sup YM/ - a quantity relevant in quenched lattice calculations - is shown to increase quite considerably in the presence of the iota, while chi/sub t/ is reduced and may even vanish. Axial couplings are consistent with the suppression expected for a singlet glueball, and give a small width for iota → 2y less than 3 keV

What energy does gravity unite with grand unified theories in the early universe

International Nuclear Information System (INIS)

Sivaram, C.

1987-01-01

Unification of gravity with GUTs is usually expected at the Planck energy E/sub PI/ ∼ 10 19 GeV. However, the vastly different values of the two couplings at E/sub PI/ (α/sub GUT/ E/sub PI/ with a single dimensionless coupling constant (α/sub U/ << 1) and described by a scale-invariant action quadratic in the Weyl curvature (with Yang-Mills fields). Breaking of scale invariance at E/sub PI/ then separates the interactions into gravity, now described by a Hilbert action with a dimensional G and GUTs with a dimensionless α/sub GUT/ and YM action. Problems with Klein-Kaluza unification of gravity with GUTs are also discussed in this context

Explaining the Mind: Problems, Problems

OpenAIRE

Harnad, Stevan

2001-01-01

The mind/body problem is the feeling/function problem: How and why do feeling systems feel? The problem is not just "hard" but insoluble (unless one is ready to resort to telekinetic dualism). Fortunately, the "easy" problems of cognitive science (such as the how and why of categorization and language) are not insoluble. Five books (by Damasio, Edelman/Tononi...

Coordination of International Risk-Reduction Investigations by the Multilateral Human Research Panel for Exploration

Science.gov (United States)

Charles, John B.; Bogomolov, Valery V.

2015-01-01

Effective use of the unique capabilities of the International Space Station (ISS) for risk reduction on future deep space missions involves preliminary work in analog environments to identify and evaluate the most promising techniques, interventions and treatments. This entails a consolidated multinational approach to biomedical research both on ISS and in ground analogs. The Multilateral Human Research Panel for Exploration (MHRPE) was chartered by the five ISS partners to recommend the best combination of partner investigations on ISS for risk reduction in the relatively short time available for ISS utilization. MHRPE will also make recommendations to funding agencies for appropriate preparatory analog work. In 2011, NASA's Human Research Program (HRP) and the Institute of Biomedical Problems (IBMP) of the Russian Academy of Science, acting for MHRPE, developed a joint US-Russian biomedical program for the 2015 one-year ISS mission (1YM) of American and Russian crewmembers. This was to evaluate the possibilities for multilateral research on ISS. An overlapping list of 16 HRP, 9 IBMP, 3 Japanese, 3 European and 1 Canadian investigations were selected to address risk-reduction goals in 7 categories: Functional Performance, Behavioral Health, Visual Impairment, Metabolism, Physical Capacity, Microbial and Human Factors. MHRPE intends to build on this bilateral foundation to recommend more fully-integrated multilateral investigations on future ISS missions commencing after the 1YM. MHRPE has also endorsed an on-going program of coordinated research on 6-month, one-year and 6-week missions ISS expeditions that is now under consideration by ISS managers. Preparatory work for these missions will require coordinated and collaborative campaigns especially in the psychological and psychosocial areas using analog isolation facilities in Houston, Köln and Moscow, and possibly elsewhere. The multilateral Human Analogs research working group (HANA) is the focal point of those

Comparison of New and Traditional Culture-Dependent Media for Enumerating Foodborne Yeasts and Molds.

Science.gov (United States)

Beuchat, Larry R; Mann, David A

2016-01-01

Fifty-six foods and food ingredients were analyzed for populations of naturally occurring yeasts and molds using Petrifilm rapid yeast and mold (RYM) count plates, Petrifilm yeast and mold (YM) count plates, dichloran rose bengal chloramphenicol (DRBC) agar plates, acidified potato dextrose agar (APDA) plates, and dichloran 18% glycerol (DG18) agar plates. Colonies were counted after incubating plates for 48, 72, and 120 h at 25°C. Of 56 foods in which either yeasts or molds were detected on at least one medium incubated for 120 h, neither yeasts nor molds were detected in 55.4, 73.2, 21.4, 19.6, and 71.4% of foods plated on the five respective media and incubated for 48 h; 10.7, 14.3, 3.6, 1.8, and 19.6% of foods were negative after 72 h, and 3.6, 1.8, 0, 0, and 0% of foods were negative after 120 h. Considering all enumeration media, correlation coefficients were 0.03 to 0.97 at 48 h of incubation; these values increased to 0.75 to 0.99 at 120 h. Coefficients of variation for total yeasts and molds were as high as 30.0, 30.8, and 27.2% at 48, 72, and 120 h, respectively. The general order of performance was DRBC = APDA > RYM Petrifilm > YM Petrifilm ≥ DG18 when plates were incubated for 48 h, DRBC > APDA > RYM Petrifilm > YM Petrifilm ≥ DG18 when plates were incubated for 72 h, and DRBC > APDA > RYM Petrifilm > YM Petrifilm > DG18 when plates were incubated for 120 h. Differences in performance among media are attributed to the diversity of yeasts and molds likely to be present in test foods and differences in nutrient, pH, and water activity requirements for resuscitation of stressed cells and colony development.

The Deployment Life Study. Appendixes

Science.gov (United States)

2014-01-01

hyperactivity SdQ (Goodman, 1997) x x x x Child peer relationships SdQ (Goodman, 1997) x x x x Child prosocial behavior SdQ (Goodman, 1997) x x x x...2 Th e d ep lo ym en t Life Stu d y: M eth o d o lo g ical O verview an d B aselin e Sam p le d escrip tio n Table A.1 List of Constructs and...Life Study x x List o f C o n stru cts an d M easu res fo r th e d ep lo ym en t Life Stu d y 3 Survey Topic Measure Source Service Member Spouse

Cost-Effective Cementitious Material Compatible with Yucca Mountain Repository Geochemistry

Energy Technology Data Exchange (ETDEWEB)

Dole, LR

2004-12-17

The current plans for the Yucca Mountain (YM) repository project (YMP) use steel structures to stabilize the disposal drifts and connecting tunnels that are collectively over 100 kilometers in length. The potential exist to reduce the underground construction cost by 100s of millions of dollars and improve the repository's performance. These economic and engineering goals can be achieved by using the appropriate cementitious materials to build out these tunnels. This report describes the required properties of YM compatible cements and reviews the literature that proves the efficacy of this approach. This report also describes a comprehensive program to develop and test materials for a suite of underground construction technologies.

Non-perturbative effects in 2d CPN-1 model and 4d YM theory. A ZN toron approach

International Nuclear Information System (INIS)

Zhitnitsky, A.R.

1992-01-01

A lot of different problems such as: Fractional topological charge, torons, Z N -symmetry, θ-dependence, confinement, U(1)-problem and all that are discussed in 2d CP N-1 model and 4d gluodynamics. A comprehensive topological classification of torons (the toron is a self-dual solution with topological number Q=1/N) is formulated and their interaction is founded in the quasiclassical approximation. It turns out that the number of different kinds of torons is equal to N, and that they are classified by the weights μ of fundamental representation of the group SU(N). Moreover, an interaction of these torons is Coulomb-like ∝Σ ij μ i μ j ln(x i -x j ) 2 and this gas can be expressed as a field theory of the Toda type. The expectation of different quantities (the vacuum energy, the topological density, the Wilson loop operator) are calculated using this effective field theory. All results (confinement, correct dependence on θ, and so on) are precisely what is well known from different considerations. The disorder parameter M is introduced and the corresponding vacuum expectation value is calculated ∝exp(2πik/N) in agreement with 't Hooft's conjecture about properties of in the confinement phase. The hypothesis of abelian dominance and corresponding Weyl Z N symmetry is realized in this approach in an automatic way. (orig.)

The absence of MyD88 has no effect on the induction of alternatively activated macrophage during Fasciola hepatica infection

Directory of Open Access Journals (Sweden)

Luo HongLin

2011-11-01

Full Text Available Abstract Background Alternatively activated macrophages (AAMϕ play important roles in allergies and responses to parasitic infections. However, whether signaling through toll-like receptors (TLRs plays any role in AAMϕ induction when young Fasciola hepatica penetrates the liver capsule and migrates through the liver tissue is still unclear. Results The data show that the lack of myeloid differentiation factor 88 (MyD88 has no effect on the AAMϕ derived from the bone marrow (BMMϕ in vitro and does not impair the mRNA expression of arginase-1, resistin-like molecule (RELMα, and Ym1 in BMMϕs. The Th2 cytokine production bias in splenocytes was not significantly altered in F. hepatica-infected mice in the absence of MyD88 in vitro and in the pleural cavity lavage in vivo. In addition, MyD88-deficiency has no effect on the arginase production of the F. hepatica elicited macrophages (Fe Mϕs, production of RELMα and Ym1 proteins and mRNA expression of Ym1 and RELMα of macrophages in the peritoneal cavity 6 weeks post F. hepatica infection. Conclusions The absence of MyD88 has no effect on presence of AAMϕ 6 weeks post F. hepatica infection.

Gender Mainstreaming in Poverty Eradication and the Millenium ...

International Development Research Centre (IDRC) Digital Library (Canada)

... market and partly in response to new opportunities generated by globalization. ... Naila Kabeer is Professorial Fellow at the Institute of Development Studies, ... She is a social economist and has been involved in teaching, research, and ...

Pulsed Power: Sandia's Plans for the New Millenium

International Nuclear Information System (INIS)

Quintenz, Jeffrey P.

2000-01-01

Pulsed power science and engineering activities at Sandia National Laboratories grew out of a programmatic need for intense radiation sources to advance capabilities in radiographic imaging and to create environments for testing and certifying the hardness of components and systems to radiation in hostile environments. By the early 1970s, scientists in laboratories around the world began utilizing pulsed power drivers with very short (10s of nanoseconds) pulse lengths for Inertial Confinement Fusion (ICF) experiments. In the United States, Defense Programs within the Department of Energy has sponsored this research. Recent progress in pulsed power, specifically fast-pulsed-power-driven z pinches, in creating temperatures relevant to ICF has been remarkable. Worldwide developments in pulsed power technologies and increased applications in both defense and industry are contrasted with ever increasing stress on research and development tiding. The current environment has prompted us at Sandia to evaluate our role in the continued development of pulsed power science and to consider options for the future. This presentation will highlight our recent progress and provide an overview of our plans as we begin the new millennium

With Black Athena into the third millenium CE

NARCIS (Netherlands)

Binsbergen, van W.M.J.; Docter, R.F.; Moormann, E.M.

1998-01-01

In 1987 and 1991 Martin Bernal published two volumes on the Afroasiatic roots of classical civilization. His theory that ancient Greek culture derived from Egypt and Phoenicia opened a discussion known as the debate on 'Black Athena'. This article sorts out whatever lasting contribution Bernal has

1ST International Conference on Small Satellites: New Technologies, Achievements, Problems And Prospects For International Co-Operation In The New Millenium.

Science.gov (United States)

1998-01-01

821798). May 25-28, 1998. Friedrichshafen , Germany. P.507-510. 3. Didier Massonnet, Producing ground deformation maps automatically: the DIAPASON...In Proc. of European Conference on Synthetic Aperture Radar (EUSAR󈨦). May 25-28, 1998. Friedrichshafen , Germany. P.237-240. 5. Z. Bergen, D...EjIH3aBeTHH, n. IIlHpOKOB Synthetic Aperture Radar (EUSAR󈨦). May 25-28, 1998. Friedrichshafen , Germany. P.503-506. 8. U.Wegmuller, SAR Processing

1ST International Conference on Small Satellites: New Technologies, Achievements, Problems and Prospects for International Co-Operation in the New Millenium

Science.gov (United States)

1998-01-01

degradation , and to detect, track and map airborne contaminants. Spe- cific, environmentally-directed science objectives of the RAMOS program include the ...Northeast Northeast Cerrado , Northeast Amazon, Northeast Amazon, Northeast Amazon In order to fulfill these applications, the SSR will carry an...efficiency and lack of coordination of the conservancy activity, a significant environmental degradation has been occurring. Industry-developed regions

The Yucca Mountain Repository - Too Little, Too Late

International Nuclear Information System (INIS)

Eriksson, L.G.; Pentz, D.L.

2009-01-01

In 2008, the U.S. Department of Energy (US DOE) announced that the nation's first (and only pursued) deep geological disposal system (repository) for 70,000 metric tonnes of spent nuclear fuel (SNF) and other high-level radioactive waste (HLW) at the Yucca Mountain (YM) site in Nevada would: 1. Not be able to accommodate the projected stockpile of utility-generated SNF beyond 2010. 2. Open no earlier than in 2020, i.e., more than 22 years behind the statutory-mandated opening date. In the meantime, the US DOE is legally obligated to compensate the utilities from January 31, 1998, until it takes title to the utilities' SNF. In 2005 when the YM SNF repository was projected to open in 2010, the utilities estimated that, depending upon how close to 2010 the YM repository opened, the 'breach-of-contract' compensation could be in the range of between 100 billion and 300 billion U.S. dollars ($300 B), which would exceed the 2008 projected life-cycle cost of $96 B for the YM repository. It thus seems appropriate to look beyond the YM repository and call upon the U.S. Congress to promptly act and open new avenues allowing the US DOE to more timely and cost-effectively take title to both existing and pending SNF the current fleet of 104 reactors will generate through the next 60 years. Options for SNF arising from an additional 50 reactors should also be provided. Based on our more than 60 years of combined involvement in nuclear waste management in the USA and abroad, we submit the following industrial-scale-proven, repository-related, nuclear-waste-management and disposition solutions for prompt Congressional consideration and action: 1. An increase in the disposal capacity (and perhaps mission) of the YM repository. 2. Prompt establishment of at least one large federal monitored retrievable storage (MRS) facility for utility-generated SNF. 3. Continued research in reprocessing options of existing and pending SNF with defined milestones. 4. Resurrection of a second

Zabytkowa architektura drewniana jako element zachowania walorów historycznych miast na Podlasiu

Directory of Open Access Journals (Sweden)

Aleksander Owerczuk

2018-04-01

Full Text Available Miasta ulegają ciągłym przeobrażeniom. Nowy kształt urbanistyczny i nowa zabudowa wkraczają do dzielnic historycznych miast. Zachowana zabytkowa architektura przeważnie nie zawiera spektakularnych obiektów. Natomiast jako całość jest cennym świadkiem epoki. W miasteczkach nierzadko ważną rolę odgrywa zabudowa drewniana, chociaż przeważnie zachowana w szczątkowym stanie. Na Podlasiu duże nasycenie zabudową drewnianą było charakterystyczne dla małych miast. Jednym z nich jest Bielsk Podlaski. Na jego przykładzie zostanie omówiony problem zmiany dawnego charakteru miasta, którego ważnym elementem była architektura drewniana.

Landforms and Landform Evolution in West Germany: International Conference on Geomorphology (2nd) Held in Frankfurt am Main on 3-9 September 1989. CATENA Supplement 15

Science.gov (United States)

1989-01-01

Lakes 107 9. Hans- Rudolf Bork Soil erosion during the past millenium in central Europe and its significance within the geomorphodynamics of the...Institut der RWTH Aachen SEMMEL, A. (1980): Geomorphologie der Bun- Templergraben 55 desrepublik Deutschland. Steiner , Wiesbaden, D-5100 Aachen 4th...Hauptabdachung am Rhein- 250 m. The late Tertiary and Quaternary durchbruch bei Bingen und im Gebiet der Id- Steiner Querfurche, Westdeutschland. Z. Geo

No Problem? No Research, Little Learning ... Big Problem!

Directory of Open Access Journals (Sweden)

Fernando Ornelas Marques

2012-06-01

Full Text Available The motivation to carry out this study stemmed from the generalized perception that nowadays youth lacks the skills for the 21st century. Especially the high-level competences like critical thinking, problem solving and autonomy. Several tools can help to improve these competences (e.g. the SCRATCH programming language, but, as researchers and educators, we are mostly concerned with the skill to recognize problems. What if we do not find problems to solve? What if we do not even feel the need to find or solve problems? The problem is to recognize the problem; the next step is to equate the problem; finally we have to feel the need to solve it. No need? No invention. Recognizing a problem is probably the biggest problem of everyday life, because we are permanently faced with problems (many ill-defined problems, which we need to identify, equate and solve.

Class and Home Problems: Optimization Problems

Science.gov (United States)

Anderson, Brian J.; Hissam, Robin S.; Shaeiwitz, Joseph A.; Turton, Richard

2011-01-01

Optimization problems suitable for all levels of chemical engineering students are available. These problems do not require advanced mathematical techniques, since they can be solved using typical software used by students and practitioners. The method used to solve these problems forces students to understand the trends for the different terms…

Uczestnictwo w lekcjach wychowania fizycznego a rozwój kultury fizycznej po zakończeniu etapu edukacyjnego

Directory of Open Access Journals (Sweden)

Ewelina Kozłowska

2015-04-01

Full Text Available Wprowadzenie i cel pracy: Regularna aktywność fizyczna stanowi integralny element właściwego stylu życia, niezbędny do prawidłowego rozwoju dzieci i młodzieży. Uznaje się ją za najlepszą niefarmakologiczną metodę pierwotnej i wtórnej prewencji większości schorzeń stanowiących współcześnie główną przyczynę śmierci – tzw. chorób cywilizacyjnych. Celem pracy jest określenie związku między uczestnictwem w lekcjach wychowania fizycznego w dzieciństwie a aktywnością ruchową w życiu dorosłym. Materiał i metoda: Badaniem została objęta grupa 937 losowo wybranych pracowników biurowych zatrudnionych na terenie województwa lubelskiego. Zastosowaną metodą badawczą był sondaż diagnostyczny z wykorzystaniem autorskiego kwestionariusza ankiety. Zależność statystyczną pomiędzy aktywnym uczestnictwem na lekcjach wychowania fizycznego a aktywnością ruchową w życiu dorosłym sprawdzano przy użyciu testu χ2 Pearsona. Wyniki: Respondenci systematycznie ćwiczący na lekcjach w-f częściej podejmują czynną formę odpoczynku w życiu dorosłym (p

Neuronally mediated contraction responses of guinea-pig stomach smooth muscle preparations: modification by benzamide derivatives does not reflect a dopamine antagonist action.

Science.gov (United States)

Costall, B; Naylor, R J; Tan, C C

1984-06-15

The actions of the substituted benzamide derivatives metoclopramide, clebopride, YM-09151-2, tiapride, (+)- and (-)-sulpiride and (+)- and (-)-sultopride, and the dopamine antagonists haloperidol and domperidone, were studied on the responses to field stimulation (0.125-10 Hz) of smooth muscle strips taken from cardia, fundus, body and antral regions of the longitudinal and circular muscle of guinea-pig stomach. Field stimulation of the longitudinal strips caused contraction responses which were antagonised by atropine (but not by prazosin, yohimbine, propranolol or methysergide) to indicate a muscarinic cholinergic involvement. Antagonism of the contractions revealed or enhanced relaxation responses mediated via unidentified mechanisms (resistant to cholinergic and adrenergic antagonists). Metoclopramide enhanced the field stimulation-induced contractions of the stomach smooth muscle preparations via atropine sensitive mechanisms but failed to attenuate the field stimulation-induced relaxation responses. Clebopride's action closely followed that of metoclopramide but YM-09151-2 only enhanced the contraction responses of the longitudinal muscle preparations. Other dopamine antagonists, (+)- and (-)-sulpiride, (+)- and (-)-sultopride, tiapride, haloperidol and domperidone failed to facilitate contraction to field stimulation of any stomach tissue. Thus, the actions of metoclopramide, clebopride and YM-09151-2 to facilitate contraction to field stimulation of stomach smooth muscle are mediated via a muscarinic cholinergic mechanism and are not the consequence of an antagonism at any recognisable dopamine receptor.

N = (2,0) self-dual non-Abelian tensor multiplet in D = 3 + 3 generates N = (1,1) self-dual systems in D = 2 + 2

Science.gov (United States)

Nishino, Hitoshi; Rajpoot, Subhash

2018-03-01

We formulate an N = (2 , 0) system in D = 3 + 3 dimensions consisting of a Yang-Mills (YM)-multiplet (ˆ μ ˆ IA, λˆI), a self-dual non-Abelian tensor multiplet (ˆ μ ˆ ν ˆ IB, χˆI ,φˆI), and an extra vector multiplet (C ˆ μ ˆ IC, ρˆI). We next perform the dimensional reductions of this system into D = 2 + 2, and obtain N = (1 , 1) systems with a self-dual YM-multiplet (AIμ ,λI), a self-dual tensor multiplet (BIμν , χI , φI), and an extra vector multiplet (CIμ , ρI). In D = 2 + 2, we reach two distinct theories: 'Theory-I' and 'Theory-II'. The former has the self-dual field-strength Hμν(+)I of CIμ already presented in our recent paper, while the latter has anti-self-dual field strength Hμν(-)I. As an application, we show that Theory-II actually generates supersymmetric-KdV equations in D = 1 + 1. Our result leads to a new conclusion that the D = 3 + 3 theory with non-Abelian tensor multiplet can be a 'Grand Master Theory' for self-dual multiplet and self-dual YM-multiplet in D = 2 + 2, that in turn has been conjectured to be the 'Master Theory' for all supersymmetric integrable theories in D ≤ 3.

The interactive effect of paternal problem drinking and maternal problem drinking on adolescent internalizing problems.

Science.gov (United States)

Ohannessian, Christine McCauley

2015-11-01

This study examined the effects of both paternal problem drinking and maternal problem drinking on adolescent internalizing problems (depression and anxiety symptomatology). Surveys were administered to 566 10th and 11th grade students from the Mid-Atlantic region of the U.S. in the spring of 2007 and again in the spring of 2008. Although significant main effects were not observed, significant interactions were found between paternal problem drinking and maternal problem drinking for internalizing problems, especially for boys. In general, these interactions indicated that when paternal problem drinking was high, depression symptomatology and anxiety symptomatology were lower if maternal problem drinking was low. Findings from this study highlight the need to consider both paternal and maternal problem drinking when examining the effects that parental problem drinking may have on adolescent adjustment. Copyright © 2015 Elsevier Ltd. All rights reserved.

Yerba mate, coffee and tobacco: their possible neuroprotecting role in Uruguayan patients suffering from Parkinson Disease, Montevideo, 2016

Directory of Open Access Journals (Sweden)

Lucía Amestoy

2017-11-01

Full Text Available Diversos reportes internacionales han demostrado que existen factores genéticos y ambientales que podrían predisponer al desarrollo de la Enfermedad de Parkinson (EP. Dichos estudios muestran la existencia de una relación inversa entre el consumo de tabaco y café y la EP, viéndose una relación dependiente de la dosis. La Yerba Mate (YM también ha mostrado, a nivel regional, dicha relación entre el riesgo de desarrollar EP y el consumo de YM. El objetivo es evaluar la posible asociación neuroprotectora entre el hábito de consumo prolongado y sostenido de la yerba mate y/o café y/o tabaco y el riesgo de desarrollar la EP. Para ello se realizó un estudio caso-control entre individuos con EP y controles sin EP. La exposición se midió el consumo e intensidad de YM, café y de tabaco. Se obtuvieron sus respectivos Odds Ratio (OR y su análisis en conjunto mediante regresión logística. Se analizaron los resultados de 128 casos y 256 controles. Tanto el consumo de YM como de tabaco, evidenció una relación inversa entre su consumo y el riesgo de desarrollar EP, OR: 0.56 (IC 95%, 0.33-0.95; p= 0.032 y OR: 0.46 (IC 95%, 0.25-0.85; p=0.013, respectivamente. El consumo de café se mostró como factor de riesgo para EP: OR: 2.04 (IC 95%, 1.21-3.44; p=0.007. El análisis multivariado muestra que la única variable que se mantiene como factor de riesgo fue el café. Concluimos que este trabajo, confirma en general buena parte de los datos ya reportados regional y mundialmente en cuanto a factores neuroprotectores ambientales de la EP.

Effect of combined radiotherapy, hyperthermia, radioprotective agent and hypoxic cell sensitizer on mice testes

Energy Technology Data Exchange (ETDEWEB)

Nakano, Yasuhiko

1985-08-01

Application of hyperthermia was executed by immersing pelvis, testes and legs of mice in a thermostatically controlled water bath. Irradiation was carried out using Toshiba KXC-18 type X-ray therapy machine. Mice were killed 30 days after treatment. The testis weights obtained after hypertheramia alone were compared with that of the control and the relative testis weight ratios were calculated. The testis weights of mice treated for 5, 10, 20 and 40 min. in 40 deg C water and for 5 and 10 min. in 43 deg C water were not significantly different from the control. Their weights were reduced when treated for 20 min. in 43 deg C water and for 5 min. in 46 deg C water and their testis weight ratios were 0.81 and 0.46, respectively. The testis weights of irradiated mice decreased to about 45 % of the control at 250 rad. Beyond this dose, reduction of their weights was slowed down and testis weight at 1,000 rad was 28 %. There was not significantly difference between the relative testis weight ratios of the irradiation alone and that of the radiotherapy combined with YM-08310 (S-2-)3-aminopropylamino) ethyl phosphorothioic acid monohydrate). But when hyperthermia was added to their treatment, the effectiveness of the YM-08310 was slightly increased. The relative testis weight ratio on 400 rad X-ray combined with YM-08310 was 0.32 of the control, while its ratio on the radiotherapy and YM-08310 combined with the hyperthermia (43 deg C, 10 min.) was 0.43. (p < 0.01). The misonidazole treatments at 50, 100 and 200 rads were found to be effectuve. Radiation alone gave the relative testis weight ratios of 0.78, 0.71 and 0.49, respectively. In contrast, its ratios on the irradiation combined with the misonidazole were 0.57 (p < 0.01), 0.46 (p < 0.01) and 0.41 (p < 0.001). But, the additional hyperthermia combined with their treatment was found to be ineffective. (J.P.N.).

Discrepancies in 14C dating as illustrated from the Egyptian new and middle kingdoms and from the Aegean bronze age and neolithic

International Nuclear Information System (INIS)

Hood, S.

1978-01-01

14 C dates available for the Middle and New Kingdoms in Egypt and for the Bronze Age and Neolithic in the Aegean are examined. The possibility is explored that calibrated dates vary from tree-ring dates by different margins in Egypt and the Aegean during the second millenium B.C. Apparent inconsistencies between 14 C dates from different Neolithic sites in the Aegean area are also noted. (author)

Ranked solutions of the matric equation A1X1=A2X2

Directory of Open Access Journals (Sweden)

A. Duane Porter

1980-01-01

Full Text Available Let GF(pz denote the finite field of pz elements. Let A1 be s×m of rank r1 and A2 be s×n of rank r2 with elements from GF(pz. In this paper, formulas are given for finding the number of X1,X2 over GF(pz which satisfy the matric equation A1X1=A2X2, where X1 is m×t of rank k1, and X2 is n×t of rank k2. These results are then used to find the number of solutions X1,…,Xn, Y1,…,Ym, m,n>1, of the matric equation A1X1…Xn=A2Y1…Ym.

Direct Problems and Inverse Problems in Biometric Systems

OpenAIRE

Mihailescu Marius Iulian

2013-01-01

The article purpose is to describe the two sides of biometrics technologies, direct problems and inverse problems. The advance that we face today in field of Information Technology makes Information Security an inseparable part. The authentication has a huge role when we deal about security. The problems that can appear in implementing and developing biometrics systems is raising many problems, and one of the goal of this article is to focus on direct and inverse problems which is a new and c...

Hemiequilibrium problems

Directory of Open Access Journals (Sweden)

Muhammad Aslam Noor

2004-01-01

Full Text Available We consider a new class of equilibrium problems, known as hemiequilibrium problems. Using the auxiliary principle technique, we suggest and analyze a class of iterative algorithms for solving hemiequilibrium problems, the convergence of which requires either pseudomonotonicity or partially relaxed strong monotonicity. As a special case, we obtain a new method for hemivariational inequalities. Since hemiequilibrium problems include hemivariational inequalities and equilibrium problems as special cases, the results proved in this paper still hold for these problems.

Beyond Gamification:From Problem-solving to Problem-making

OpenAIRE

Ruffino, Paolo

2014-01-01

The problem I would like to highlight in this contribution is that gamification has been thought about too much as a tool for problem solving, and not enough as a tool for problem making. The idea of gamification as a tool for problem making could be more useful – although maybe paradoxically. As long as a technique is presented as a method for the solution of problems it can too easily become an authoritative proposal, which takes one solution and vision as necessarily better than the others...

[Health challenges as the second millenium is ending. Conceptual epidemiology, social pathology, medicine and professional ethics].

Science.gov (United States)

Velasco Suárez, M

1990-01-01

In this article it is outlined the work of doctor Bustamante in fighting against diseases such as yellow fever, typhus, malaria, and smallpox; and the development and impel that this professional gave to preventive and social medicine is pointed out. It is established that health care professionals currently must not only highly studied and prepared, as they should manage all features related with public health, but also change-men-and-women who are capable to influence future generations, which will be the responsible in relocating men at the equilibrium point concerned to their health. Said equilibrium point is not only modified in its biopsychosocial aspect, but also its essence is deeply affected. This paper is a warning to physicians to fight together in response to humanity, that has set their confidence in them, as the current problem of drugs and dependence to drugs unhinges everything wholeness. To doctor Suarez is intolerable that, in spite of technological advances in the world, yet exist deaths caused by pneumonia or diarrhea. The hazards of the century are frightened: nuclear war and AIDS; but the characteristics that have distinguished human species and allowed its survival and superation are trusted: mental activity, ability of judgement, and consciousness; which are valuable for a deep philosophic discussion that allows us to continue our advance. An enumeration of the medicine achievements in this century is made.

Balance Problems

Science.gov (United States)

... often, it could be a sign of a balance problem. Balance problems can make you feel unsteady. You may ... related injuries, such as a hip fracture. Some balance problems are due to problems in the inner ...

A Paradigm for the Next Millenium: Health Information Science.

Science.gov (United States)

Sadler, Lewis

1991-01-01

Described is a curriculum for a new multidisciplinary science-Health Information Science-that incorporates aspects of computer science, cognitive psychology, bioengineering, biomedical visualization, medicine, dentistry, anthropology, mathematics, library science, and the visual arts. The situation of the medical illustration profession is…

Effective Communication for the Present and Into the Millenium

Science.gov (United States)

Heard, Pamala D.

1999-01-01

This research is related to educational technology, in the Education Programs Department. I will be exploring the NASA/Marshall Alumni Web Page (ALEX) and NASA/MSFC Education Programs Department Home Page. My research will focus on established goals and objectives. I will investigate ways in which the Education Programs Department can better utilize their products, for its internal and external customers. The strengths and weakness of each project will be examined. The customers needs are examined in an attempt to determine the most effective approach needed to utilize these educational products.

Achieving the millenium and sustainable development goals in Africa

African Journals Online (AJOL)

The point that African continent has been trying to solve its development challenges will be an overstatement. One of the major efforts was the decision taken at the United Nations (UN) Millennium Summit in September 2000 where the Millennium Development Goals (MDGs) was adopted as a framework for the continents ...

Banyule unlocks local water

International Nuclear Information System (INIS)

Collins, Richard

2014-01-01

Banyule Council, Victoria has launched one of Melbourne's biggest stormwater harvesting schemes. After the Millenium Drought in the early 2000s, ratepayers and the community alike prompted the council to undertake a detailed water management study to improve water options for the many reserves and parklands. They launched three projects, with differing technical site issues, using such designs as gross pollutant traps, sediment ponds, bio-filtration, wetlands, and underground storage using waterproof geomembrane liners.

Social complexity in the third millennium cal BC in southern Portugal

OpenAIRE

Soares, Joaquina

2016-01-01

The starting point of this paper is the extensive archaeological fieldwork developed at the Chalcolithic fortification of Porto das Carretas on the left bank of the Middle Guadiana River (Soares, 2013). The well-preserved stratigraphy and correlated radiocarbon dates of Porto das Carretas enabled a new and deep insight into the third millennium cal BC, displaying environmental, economic and social transformations from the first to the second half of the millenium. Furhermore, the integration ...

Illustration of sampling-based approaches to the calculation of expected dose in performance assessments for the proposed high level radioactive waste repository at Yucca Mountain, Nevada.

Energy Technology Data Exchange (ETDEWEB)

Helton, Jon Craig (Arizona State University, Tempe, AZ); Sallaberry, Cedric J. PhD. (.; .)

2007-04-01

A deep geologic repository for high level radioactive waste is under development by the U.S. Department of Energy at Yucca Mountain (YM), Nevada. As mandated in the Energy Policy Act of 1992, the U.S. Environmental Protection Agency (EPA) has promulgated public health and safety standards (i.e., 40 CFR Part 197) for the YM repository, and the U.S. Nuclear Regulatory Commission has promulgated licensing standards (i.e., 10 CFR Parts 2, 19, 20, etc.) consistent with 40 CFR Part 197 that the DOE must establish are met in order for the YM repository to be licensed for operation. Important requirements in 40 CFR Part 197 and 10 CFR Parts 2, 19, 20, etc. relate to the determination of expected (i.e., mean) dose to a reasonably maximally exposed individual (RMEI) and the incorporation of uncertainty into this determination. This presentation describes and illustrates how general and typically nonquantitive statements in 40 CFR Part 197 and 10 CFR Parts 2, 19, 20, etc. can be given a formal mathematical structure that facilitates both the calculation of expected dose to the RMEI and the appropriate separation in this calculation of aleatory uncertainty (i.e., randomness in the properties of future occurrences such as igneous and seismic events) and epistemic uncertainty (i.e., lack of knowledge about quantities that are poorly known but assumed to have constant values in the calculation of expected dose to the RMEI).

A performance assessment review tool for the proposed radioactive waste repository at Yucca Mountain, Nevada, USA

International Nuclear Information System (INIS)

Mohanty, Sitakanta; Codell, Richard

2000-01-01

The U.S. Nuclear Regulatory Commission (NRC), with the assistance of the Center for Nuclear Waste Regulatory Analyses, has developed a Total-system Performance Assessment (TPA) Code to assist in evaluating the performance of the Yucca Mountain (YM) High-Level Waste Repository in Nevada, proposed by the U.S. Department of Energy (DOE). The proposed YM repository would be built in a thick sequence of partially saturated volcanic tuff above the water table. Among the unique challenges of this environment are (1) the transport of radionuclides would take place partially through highly heterogeneous unsaturated rock; (2) the waste packages (WPs) would be generally exposed to oxidizing conditions, and (3) water either infiltrating from the surface or recirculating because of decay heat may drip onto the WPs. Tools such as the TPA code and embedded techniques for evaluating YM performance are aimed at (1) determining the parameters and key parts of the repository system that have the most influence on repository performance; (2) performing alternative conceptual models studies, especially with bounding models; (3) estimating the relative importance of the physical phenomena that lead to human exposure to radionuclides; and (4) improving NRC staff capabilities in performance assessment and associated license application reviews. This paper presents an overview of the NRC conceptual framework, approach to conducting system-level sensitivity analyses for determining influential parameters, and alternative conceptual model studies to investigate the effect of model uncertainties. (author)

Bioprospecting Sponge-Associated Microbes for Antimicrobial Compounds.

Science.gov (United States)

Indraningrat, Anak Agung Gede; Smidt, Hauke; Sipkema, Detmer

2016-05-02

Sponges are the most prolific marine organisms with respect to their arsenal of bioactive compounds including antimicrobials. However, the majority of these substances are probably not produced by the sponge itself, but rather by bacteria or fungi that are associated with their host. This review for the first time provides a comprehensive overview of antimicrobial compounds that are known to be produced by sponge-associated microbes. We discuss the current state-of-the-art by grouping the bioactive compounds produced by sponge-associated microorganisms in four categories: antiviral, antibacterial, antifungal and antiprotozoal compounds. Based on in vitro activity tests, identified targets of potent antimicrobial substances derived from sponge-associated microbes include: human immunodeficiency virus 1 (HIV-1) (2-undecyl-4-quinolone, sorbicillactone A and chartarutine B); influenza A (H1N1) virus (truncateol M); nosocomial Gram positive bacteria (thiopeptide YM-266183, YM-266184, mayamycin and kocurin); Escherichia coli (sydonic acid), Chlamydia trachomatis (naphthacene glycoside SF2446A2); Plasmodium spp. (manzamine A and quinolone 1); Leishmania donovani (manzamine A and valinomycin); Trypanosoma brucei (valinomycin and staurosporine); Candida albicans and dermatophytic fungi (saadamycin, 5,7-dimethoxy-4-p-methoxylphenylcoumarin and YM-202204). Thirty-five bacterial and 12 fungal genera associated with sponges that produce antimicrobials were identified, with Streptomyces, Pseudovibrio, Bacillus, Aspergillus and Penicillium as the prominent producers of antimicrobial compounds. Furthemore culture-independent approaches to more comprehensively exploit the genetic richness of antimicrobial compound-producing pathways from sponge-associated bacteria are addressed.

Dopamine D/sub 2/ and D/sub 1/ receptors: biochemical characterization

Energy Technology Data Exchange (ETDEWEB)

Niznik, H B

1986-01-01

In order to label dopamine D/sub 2/ receptors reversibly and selectively the potent substituted benzamide neuroleptic, YM-09151-2, was tritium labeled and its binding characteristics to striatal homogenates investigated. (/sup 3/H) YM-09151-2 bound to D/sub 2/ receptors with high affinity in a specific, saturable, reversible and sodium dependent fashion, displaying an appropriate pharmacological D/sub 2/ receptor profile. (/sup 3/H) YM-09151-2 appears to be the ligand of choice for labeling D/sub 2/ receptors since it displays approximately 20-fold lower affinity for serotonergic S/sub 2/ receptors than does (/sup 3/H) spiperone. As an initial step towards the molecular identification of the ligand binding subunit of the striatal D/sub 2/ receptor, photolabile analogues of the substituted benzamide clebopride were synthesized and their reversible and irreversible binding interactions to D/sub 2/ receptors characterized. D/sub 2/ receptor photoinactivation was prevented in a concentration and stereoselective manner by dopaminergic agonists and antagonists. In vivo biodistribution studies with (/sup 125/I) iodoazidoclebopride confirmed the ligand's ability to bind to D/sub 2/ receptor-rich regions and as such, may become a useful tool for the molecular characterization of D/sub 2/ receptor proteins. Digitonin solubilized striatal dopamine D/sub 2/ and D/sub 1/ receptors can be completely separated with full retention of biological activity by steric exclusion High Pressure Liquid Chromatography (HPLC) with corresponding Stokes radii of 7.1 and 5.6 nm.

Purinergic signaling during macrophage differentiation results in M2 alternative activated macrophages.

Science.gov (United States)

Barberà-Cremades, Maria; Baroja-Mazo, Alberto; Pelegrín, Pablo

2016-02-01

Macrophages represent a highly heterogenic cell population of the innate immune system, with important roles in the initiation and resolution of the inflammatory response. Purinergic signaling regulates both M1 and M2 macrophage function at different levels by controlling the secretion of cytokines, phagocytosis, and the production of reactive oxygen species. We found that extracellular nucleotides arrest macrophage differentiation from bone marrow precursors via adenosine and P2 receptors. This results in a mature macrophage with increased expression of M2, but not M1, genes. Similar to adenosine and ATP, macrophage growth arrested with LPS treatment resulted in an increase of the M2-related marker Ym1. Recombinant Ym1 was able to affect macrophage proliferation and could, potentially, be involved in the arrest of macrophage growth during hematopoiesis. © Society for Leukocyte Biology.

The large N limit of the topological susceptibility of Yang-Mills gauge theory

Energy Technology Data Exchange (ETDEWEB)

Ce, Marco [Scuola Normale Superiore, Pisa (Italy); INFN, Pisa (Italy); Garcia Vera, Miguel [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Humboldt Univ. Berlin (Germany). Inst. fuer Physik; Giusti, Leonardo [Milano Bicocca Univ., Milano (Italy); INFN, Milano Bicocca (Italy); Schaefer, Stefan [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC

2016-10-27

We present a precise computation of the topological susceptibility χ{sub YM} of SU(N) Yang-Mills theory in the large N limit. The computation is done on the lattice, using high-statistics Monte Carlo simulations with N=3,4,5,6 and three different lattice spacings. Two major improvements make it possible to go to finer lattice spacing and larger N compared to previous works. First, the topological charge is implemented through the gradient flow definition; and second, open boundary conditions in the time direction are employed in order to avoid the freezing of the topological charge. The results allow us to extrapolate the dimensionless quantity t{sub 0}{sup 2}χ{sub YM} to the continuum and large N limits with confidence. The accuracy of the final result represents a new quality in the verification of large N scaling.

Integral centrifuges for olive oil extraction, at the third millenium threshold. Transformation yields

Directory of Open Access Journals (Sweden)

Ranalli, Alfonso

1995-10-01

Full Text Available A new-two, phase "decanter" (able to centrifuge the oily pastes without previous addition of hot water was compared with a three-phase one, processing homogeneous lots of three olive varieties (Coratina, Nebbio and Grossa di Cassano at an industrial level. The results showed that the integral centrifuge frequently yielded higher oil outputs. Furthermore, as the vegetation water was not separated from the husk, the amount liquid effluent produced was much lower (about 10 Kg/q olives, on average. This goes towards solving the age-old and very difficult problems connected with the production of this highly polluting outflow. However, the olive cake obtained semi-liquid (with about 55-60% of moisture, making the industrial recovery of the residual oil difficult and expensive. Furthermore, the solid by-product was characterized by higher percentage values of the oil amount, higher values of the pulp/stone ratio, as well as the greater weight produced. The effluent produced in small quantities, besides being more concentrated and thus richer in fat, dry residue, phenols and o-diphenols. The COD and turbidity values were also higher. Finally, as will be referred to in detail in the second part of this work, the oils obtained were of a far higher quality, mainly for their lower oxidizability and better organoleptic characteristic, so that they are wholly comparable to those extracted by pressing or filtering. In addition, the significant reduction of processing costs, as well as the lower consumption of hot water and electrical energy, must also be emphasized.

El nuevo "decanter", a dos fases (capaz de centrifugar la pasta oleosa sin la dilución previa con agua caliente ha sido confrontado con el de a tres fases, elaborando, a nivel industrial, partidas homogéneas de tres variedades de aceitunas (Coratina, Nebbio y Grossa di Cassano. Los resultados de investigación han puesto de manifiesto que las centrifugadoras integrales permiten obtener

Enigmatic Solar Wind Disappearance Events – Do We Understand ...

Indian Academy of Sciences (India)

Solar wind disappearance—polar field reversals—transient ... unlike its high speed counterpart that emanates only from large open field regions ..... Sheeley, N. R. Jr., Swanson, E. T., Wang, Y.-M. 1991, Out of the ecliptic tests of the inverse.

BDML Datasets: 8 [SSBD[Archive

Lifescience Database Archive (English)

Full Text Available , Y.M., Stirbl, R.C., Bruck, J., and Sternberg, P.W. Paul W. Sternberg, California Institute of Technology, HHMI and Division of Biol...ogy, Sternberg Laboratory See details in Cronin et al. (2005) BMC Genetics 6, 5. CC

Preliminary characterization of slow growing rhizobial strains ...

African Journals Online (AJOL)

COMPAQ

2016-05-18

May 18, 2016 ... strains had a very slow growth rate in yeast malt (YM) agar medium, forming colonies less than 1 mm in ... dominant genus of symbiotic nitrogen-fixing bacteria ... Single colonies were picked up and checked for purity by.

Presence of D4 dopamine receptors in human prefrontal cortex: a postmortem study Presença de receptores dopaminérgicos D4 em córtex cerebral humano: um estudo post-mortem

Directory of Open Access Journals (Sweden)

Donatella Marazziti

2007-06-01

Full Text Available OBJECTIVE: The aim of our study was to explore the presence and the distribution of D4 dopamine receptors in postmortem human prefrontal cortex, by means of the binding of [³H]YM-09151-2, an antagonist that has equal affinity for D2, D3 and D4 receptors. It was therefore necessary to devise a unique assay method in order to distinguish and detect the D4 component. METHOD: Frontal cortex samples were harvested postmortem, during autopsy sessions, from 5 subjects. In the first assay, tissue homogenates were incubated with increasing concentrations of [³H]YM-09151-2, whereas L-745870, which has a high affinity for D4 and a low affinity for D2/D3 receptors, was used as the displacer. In the second assay, raclopride, which has a high affinity for D2/D3 receptors and a low affinity for D4 receptors, was used to block D2/D3. The L-745870 (500 nM was added to both assays in order to determine the nonspecific binding. RESULTS: Our experiments revealed the presence of specific and saturable binding of [³H]YM-09151-2. The blockade of D2 and D3 receptors with raclopride ensured that the D4 receptors were labeled. The mean maximum binding capacity was 88 ± 25 fmol/mg protein, and the dissociation constant was 0.8 ± 0.4 nM. DISCUSSION AND CONCLUSIONS: Our findings, although not conclusive, suggest that the density of D4 receptors is low in the human prefrontal cortex.OBJETIVO: O objetivo deste estudo foi quantificar a presença e a distribuição de receptores dopaminérgicos do tipo 4 (D4 no córtex cerebral humano em amostras post-mortem através do bloqueio com ³H-YM-09151-2 - um antagonista com afinidade equivalente pelos receptores D2, D3 e D4 - e do desenvolvimento de um método para a detecção específica do componente D4. MÉTODO: Foram obtidas amostras de córtex cerebral de cinco cadáveres. Em um primeiro ensaio, os homogeneizados de tecido cerebral foram incubados em concentrações crescentes de ³H-YM-09151-2, enquanto que o L-745

Toward Solving the Problem of Problem Solving: An Analysis Framework

Science.gov (United States)

Roesler, Rebecca A.

2016-01-01

Teaching is replete with problem solving. Problem solving as a skill, however, is seldom addressed directly within music teacher education curricula, and research in music education has not examined problem solving systematically. A framework detailing problem-solving component skills would provide a needed foundation. I observed problem solving…

Effects of Worked Examples, Example-Problem Pairs, and Problem-Example Pairs Compared to Problem Solving

NARCIS (Netherlands)

Van Gog, Tamara; Kester, Liesbeth; Paas, Fred

2010-01-01

Van Gog, T., Kester, L., & Paas, F. (2010, August). Effects of worked examples, example-problem pairs, and problem-example pairs compared to problem solving. Paper presented at the Biannual EARLI SIG meeting of Instructional design and Learning and instruction with computers, Ulm, Germany.

Open-Start Mathematics Problems: An Approach to Assessing Problem Solving

Science.gov (United States)

Monaghan, John; Pool, Peter; Roper, Tom; Threlfall, John

2009-01-01

This article describes one type of mathematical problem, open-start problems, and discusses their potential for use in assessment. In open-start problems how one starts to address the problem can vary but they have a correct answer. We argue that the use of open-start problems in assessment could positively influence classroom mathematics…

Kunstieksperdid kiruvad võidukavandit / Villu Päärt

Index Scriptorium Estoniae

Päärt, Villu, 1972-

2006-01-01

Eesti Rahva muuseumi uue hoone arhitektuurikonkursi võidutööd: 1. preemia "Memory Field" (autorid itaalia arhitekt Dan Dorell, liibanoni arhitekt Lina Ghotmeh, jaapani arhitekt Tsuyoshi Tane); 2. preemia "Gems" (autorid soome arhitektid Juho Grönholm, Antti Nousjoki, Janne Teräsvirta, Samuli Woolston); 3. preemia "Estonia is on the verge of a new millenium" (autorid austria arhitektid Alfred Bramberger, Thomas Pucher, Heidrun Steinhauser, Martin Mathy, Christa Pucher). Lähemalt tööst "Memory Field"

Lithium-Ion Battery Program Status

Science.gov (United States)

Surampudi, S.; Huang, C. K.; Smart, M.; Davies, E.; Perrone, D.; Distefano, S.; Halpert, G.

1996-01-01

The objective of this program is to develop rechargeable Li-ion cells for future NASA missions. Applications that would benefit from this project are: new millenium spacecraft; rovers; landers; astronaut equipment; and planetary orbiters. The approach of this program is: select electrode materials and electrolytes; identify failure modes and mechanisms and enhance cycle life; demonstrate Li-ion cell technology with liquid electrolyte; select candidate polymer electrolytes for Li-ion polymer cells; and develop Li-ion polymer cell technology.

Speech Problems

Science.gov (United States)

... Staying Safe Videos for Educators Search English Español Speech Problems KidsHealth / For Teens / Speech Problems What's in ... a person's ability to speak clearly. Some Common Speech and Language Disorders Stuttering is a problem that ...

Sociale problemer

DEFF Research Database (Denmark)

Christensen, Anders Bøggild; Rasmussen, Tove; Bundesen, Peter Verner

Sociale problemer kan betragtes som selve udgangspunktet for socialt arbejde, hvor ambitionen er at råde bod på problemerne og sikre, at udsatte borgere får en bedre tilværelse. Det betyder også, at diskussionen af sociale problemer er afgørende for den sociale grundfaglighed. I denne bog sætter en...... række fagfolk på tværs af det danske socialfaglige felt fokus på sociale problemer. Det diskuteres, hvad vi overhovedet forstår ved sociale problemer, hvordan de opstår, hvilke konsekvenser de har, og ikke mindst hvordan man som fagprofessionel håndterer sociale problemer i det daglige arbejde. Bogen er...... skrevet som lærebog til professionsuddannelser, hvor sociale problemer udgør en dimension, bl.a. socialrådgiver-, pædagog- og sygeplejerskeuddannelserne....

Use of response surface methodology to optimize the drying ...

African Journals Online (AJOL)

CHABI

2016-09-15

Sep 15, 2016 ... ATCC 27844, methicillin resistant S. aureus (MRSA),. Salmonella typhi R ... count (YM), bacteriocin production (BE) and the antimicrobial activity against indicator .... predicted one from the optimized model by calculating the percentage error to ..... A mathematical model considering variable diffusivity ...

Gene expression profiles in adenosine-treated human mast cells ...

African Journals Online (AJOL)

Gene expression profiles in adenosine-treated human mast cells. ... SW Kang, JE Jeong, CH Kim, SH Choi, SH Chae, SA Jun, HJ Cha, JH Kim, YM Lee, YS ... beta 4, ring finger protein, high-mobility group, calmodulin 2, RAN binding protein, ...

Repeated-batch ethanol fermentation from sweet sorghum juice by ...

African Journals Online (AJOL)

. It was found that sweet sorghum juice (SSJ) containing 100 g l-1 of total sugar without nutrient supplement could be used as the low-cost IP medium instead of the typical IP medium or yeast extract malt extract (YM) medium. Ethanol ...

Recenzija. Monografija apie filosofijos ir literatūros giminystę

Directory of Open Access Journals (Sweden)

Tomas Kačerauskas

2011-04-01

Full Text Available Prieš keletą metų neoficialiame pokalbyje J. Baranova prasitarė, kad nėra didesnio malonumo už rašymą. Tiesą sakant, buvau sužavėtas ir priblokštas ne tik dėl šios ištaros asimetrijos R. Barthes’o minčiai apie skaitymo malonumą (net erotinį. Visai kitaip apie rašymą atsiliepia A. Šliogeris (kurio filosofi jos apmąstymui J. Baranova pelnytai skiria daug dėmesio: jis mieliau nerašytų nei rašytų. Tokiais atvejais prisimenu M. Bulgakovą, kuris „tempiąs save už plaukų prie rašomojo stalo“. Rašymas daug kam siejasi su disciplina, prievarta savęs atžvilgiu, geriausiu atveju – kasdieniu įpročiu.

Effects of shading on morphology, physiology and grain yield of winter wheat

DEFF Research Database (Denmark)

Li, Huawei; Jiang, Dong; Wollenweber, Bernd

2010-01-01

In a field experiment, winter wheat (Triticum aestivum L.) cultivars Yangmai 158 (YM 158, shading tolerant) and Yangmai 11 (YM 11, shading-sensitive) were subjected to shading between jointing and maturity. Three shading treatments were applied, i.e. 92% (S1), 85% (S2) and 77% (S3) of full...... the shading treatments applied, leaf area index, length of the peduncle internode, area of the upper leaves and content of pigments increased, which favoured efficient light capture. Shading modified light quality in the canopy as indicated by increases of diffuse- and blue light fractions and a reduction...... the flag leaf, as in most cases Pn of the third and the penultimate leaves were found to increase under shading treatments. Shading increased the redistribution of dry matter from vegetative organs into grains. The responses of the morphological and physiological traits to shading are discussed in relation...

Aerobic exercise training induces skeletal muscle hypertrophy and age-dependent adaptations in myofiber function in young and older men

Science.gov (United States)

Konopka, Adam R.; Undem, Miranda K.; Hinkley, James M.; Minchev, Kiril; Kaminsky, Leonard A.; Trappe, Todd A.; Trappe, Scott

2012-01-01

To examine potential age-specific adaptations in skeletal muscle size and myofiber contractile physiology in response to aerobic exercise, seven young (YM; 20 ± 1 yr) and six older men (OM; 74 ± 3 yr) performed 12 wk of cycle ergometer training. Muscle biopsies were obtained from the vastus lateralis to determine size and contractile properties of isolated slow [myosin heavy chain (MHC) I] and fast (MHC IIa) myofibers, MHC composition, and muscle protein concentration. Aerobic capacity was higher (P 0.05) with training. Training reduced (P aerobic capacity are similar between YM and OM, while adaptations in myofiber contractile function showed a general improvement in OM. Training-related increases in MHC I and MHC IIa peak power reveal that skeletal muscle of OM is responsive to aerobic exercise training and further support the use of aerobic exercise for improving cardiovascular and skeletal muscle health in older individuals. PMID:22984247

The Markov moment problem and extremal problems

CERN Document Server

Kreĭn, M G; Louvish, D

1977-01-01

In this book, an extensive circle of questions originating in the classical work of P. L. Chebyshev and A. A. Markov is considered from the more modern point of view. It is shown how results and methods of the generalized moment problem are interlaced with various questions of the geometry of convex bodies, algebra, and function theory. From this standpoint, the structure of convex and conical hulls of curves is studied in detail and isoperimetric inequalities for convex hulls are established; a theory of orthogonal and quasiorthogonal polynomials is constructed; problems on limiting values of integrals and on least deviating functions (in various metrics) are generalized and solved; problems in approximation theory and interpolation and extrapolation in various function classes (analytic, absolutely monotone, almost periodic, etc.) are solved, as well as certain problems in optimal control of linear objects.

Problem solving stages in the five square problem.

Science.gov (United States)

Fedor, Anna; Szathmáry, Eörs; Öllinger, Michael

2015-01-01

According to the restructuring hypothesis, insight problem solving typically progresses through consecutive stages of search, impasse, insight, and search again for someone, who solves the task. The order of these stages was determined through self-reports of problem solvers and has never been verified behaviorally. We asked whether individual analysis of problem solving attempts of participants revealed the same order of problem solving stages as defined by the theory and whether their subjective feelings corresponded to the problem solving stages they were in. Our participants tried to solve the Five-Square problem in an online task, while we recorded the time and trajectory of their stick movements. After the task they were asked about their feelings related to insight and some of them also had the possibility of reporting impasse while working on the task. We found that the majority of participants did not follow the classic four-stage model of insight, but had more complex sequences of problem solving stages, with search and impasse recurring several times. This means that the classic four-stage model is not sufficient to describe variability on the individual level. We revised the classic model and we provide a new model that can generate all sequences found. Solvers reported insight more often than non-solvers and non-solvers reported impasse more often than solvers, as expected; but participants did not report impasse more often during behaviorally defined impasse stages than during other stages. This shows that impasse reports might be unreliable indicators of impasse. Our study highlights the importance of individual analysis of problem solving behavior to verify insight theory.

Problem solving stages in the five square problem

Directory of Open Access Journals (Sweden)

Anna eFedor

2015-08-01

Full Text Available According to the restructuring hypothesis, insight problem solving typically progresses through consecutive stages of search, impasse, insight and search again for someone, who solves the task. The order of these stages was determined through self-reports of problem solvers and has never been verified behaviourally. We asked whether individual analysis of problem solving attempts of participants revealed the same order of problem solving stages as defined by the theory and whether their subjective feelings corresponded to the problem solving stages they were in. 101 participants tried to solve the Five-Square problem in an online task, while we recorded the time and trajectory of their stick movements. After the task they were asked about their feelings related to insight and 67 of them also had the possibility of reporting impasse while working on the task. We have found that 49% (19 out of 39 of the solvers and 13% (8 out of 62 of the non-solvers followed the classic four-stage model of insight. The rest of the participants had more complex sequences of problem solving stages, with search and impasse recurring several times. This means that the classic four-stage model must be extended to explain variability on the individual level. We provide a model that can generate all sequences found. Solvers reported insight more often than non-solvers and non-solvers reported impasse more often than solvers, as expected; but participants did not report impasse more often during behaviourally defined impasse stages than during other stages. This shows that impasse reports might be unreliable indicators of impasse. Our study highlights the importance of individual analysis of problem solving behaviour to verify insight theory.

New underground neutrino observatory-GENIUS-in the new millenium for solar neutrinos, dark matter and double beta decay

CERN Document Server

Klapdor-Kleingrothaus, H V

2001-01-01

Double beta decay is indispensable to solve the question of the neutrino mass matrix together with nu oscillation experiments. The most sensitive experiment for eight years-the HEIDELBERG-MOSCOW experiment in Gran-Sasso-already now, with the experimental limit of (m/sub nu /)<0.26 eV excludes degenerate nu mass scenarios allowing neutrinos as hot dark matter in the Universe for the small angle MSW solution of the solar neutrino problem. It probes cosmological models including hot dark matter already now on the level of future satellite experiments MAP and PLANCK. It further probes many topics of beyond standard model physics at the TeV scale. Future experiments should give access to the multiTeV range and complement on many ways the search for new physics at future colliders like LHC and NLC. For neutrino physics GENIUS will allow to test almost all neutrino mass scenarios allowed by the present neutrino oscillation experiments. At the same time GENIUS will cover a wide range of the parameter space of pred...

Knapsack problems

CERN Document Server

Kellerer, Hans; Pisinger, David

2004-01-01

Thirteen years have passed since the seminal book on knapsack problems by Martello and Toth appeared. On this occasion a former colleague exclaimed back in 1990: "How can you write 250 pages on the knapsack problem?" Indeed, the definition of the knapsack problem is easily understood even by a non-expert who will not suspect the presence of challenging research topics in this area at the first glance. However, in the last decade a large number of research publications contributed new results for the knapsack problem in all areas of interest such as exact algorithms, heuristics and approximation schemes. Moreover, the extension of the knapsack problem to higher dimensions both in the number of constraints and in the num­ ber of knapsacks, as well as the modification of the problem structure concerning the available item set and the objective function, leads to a number of interesting variations of practical relevance which were the subject of intensive research during the last few years. Hence, two years ago ...

Problem-based Learning and Problem Finding Among University Graduate Students

OpenAIRE

Ankit, A, Ravankar; Shotaro, Imai; Michiyo, Shimamura; Go, Chiba; Taichi, Takasuka

2017-01-01

In recent years, problem-based learning (PBL) techniques have been gaining momentum in schools and university curricula around the world. The main advantage of the PBL method is that it promotes creative problem solving, improves cognition and enhances overall thought processes in learners. For most PBL-style programmes, problem solving is at the core, although the notion of problem discovery or problem finding is not seriously considered. In most cases, students are always presen...

Structure, function, pharmacology and therapeutic potential of the G protein, Gα/q,11

Directory of Open Access Journals (Sweden)

Danielle eKamato

2015-03-01

Full Text Available G protein coupled receptors are one of the major classes of cell surface receptors and are associated with a group of G proteins consisting of 3 subunits termed alpha, beta and gamma. G proteins are classified into four families according to their α subunit; Gαi, Gαs, Gα12/13 and Gαq. There are several downstream pathways of Gαq of which the best known is upon activation via GTP, Gαq activates phospholipase Cβ, hydrolysing phosphatidylinositol 4,5-biphosphate into diacylglycerol and inositol triphosphate and activating protein kinase C and increasing calcium efflux from the endoplasmic recticulum. Although G proteins, in particular the Gαq/11 are central elements in GPCR signalling, their actual roles have not yet been thoroughly investigated. The lack of research of the role on Gαq/11 in cell biology is partially due to the obscure nature of the available pharmacological agents. YM-254890 is the most useful Gαq-selective inhibitor with antiplatelet, antithrombotic and thrombolytic effects. YM-254890 inhibits Gαq signalling pathways by preventing the exchange of GDP for GTP. UBO-QIC is a structurally similar compound to YM-254890 which can inhibit platelet aggregation and cause vasorelaxation in rats. Many agents are available for the study of signalling downstream of Gαq/11. The role of G proteins could potentially represents a novel therapeutic target to block all G protein dependent mechanisms. This review will explore the range of pharmacological and molecular tools available for the study of the role of Gαq/11 in GPCR signalling.

Empirical model based on Weibull distribution describing the destruction kinetics of natural microbiota in pineapple (Ananas comosus L.) puree during high-pressure processing.

Science.gov (United States)

Chakraborty, Snehasis; Rao, Pavuluri Srinivasa; Mishra, Hari Niwas

2015-10-15

High pressure inactivation of natural microbiota viz. aerobic mesophiles (AM), psychrotrophs (PC), yeasts and molds (YM), total coliforms (TC) and lactic acid bacteria (LAB) in pineapple puree was studied within the experimental domain of 0.1-600 MPa and 30-50 °C with a treatment time up to 20 min. A complete destruction of yeasts and molds was obtained at 500 MPa/50 °C/15 min; whereas no counts were detected for TC and LAB at 300 MPa/30 °C/15 min. A maximum of two log cycle reductions was obtained for YM during pulse pressurization at the severe process intensity of 600 MPa/50 °C/20 min. The Weibull model clearly described the non-linearity of the survival curves during the isobaric period. The tailing effect, as confirmed by the shape parameter (β) of the survival curve, was obtained in case of YM (β1) was observed for the other microbial groups. Analogous to thermal death kinetics, the activation energy (Ea, kJ·mol(-1)) and the activation volume (Va, mL·mol(-1)) values were computed further to describe the temperature and pressure dependencies of the scale parameter (δ, min), respectively. A higher δ value was obtained for each microbe at a lower temperature and it decreased with an increase in pressure. A secondary kinetic model was developed describing the inactivation rate (k, min(-1)) as a function of pressure (P, MPa) and temperature (T, K) including the dependencies of Ea and Va on P and T, respectively. Copyright © 2015 Elsevier B.V. All rights reserved.

A further problem of the hard problem of consciousness | Gbenga ...

African Journals Online (AJOL)

Justifying this assertion is identified as the further problem of the hard problem of consciousness. This shows that assertions about phenomenal properties of mental experiences are wholly epistemological. Hence, the problem of explaining phenomenal properties of a mental state is not a metaphysical problem, and what is ...

Lo Peor ya ocurrió. Categorías del Postapocalipsis hispanoamericano: Alejandro Morales y Marcelo Cohen

OpenAIRE

Salvioni, Amanda

2013-01-01

The Apocalyptic Latin American Literature and its success at the turn of the millenium could be analysed by two principal points of view: as the consequence of postmodern thought, that criticizes the traditional ìsense of an endingî in terms of the collapse of all the others Grand Narratives; or as a sort of dissident discourse about globalization, in order to criticize the industrial development, the urbanization and the environmental damage in Latin America. This article focuses on both cri...

Proceedings of World Renewable Energy Congress '99

International Nuclear Information System (INIS)

Kamaruzzaman Sopian; Mohd Yusof Othman; Baharuddin Yatim

2000-01-01

The congress discussed the following subjects, 1. The role of renewable energy in the next millenium; 2. Challenges in the commercialization of renewable energy; 3. The role and agenda for renewable energy towards sustainable development. Topics covered in the technical session were biomass conversion; solar thermal technologies and systems; solar photovoltaic s; renewable energy economics, financing and policy; renewable energy education; climate and the environment; energy and architecture; energy management; wind and hydro technologies and systems; hydrogen and fuel cell

De Italo Calvino a Ricardo Piglia, do centro para a margem: o deslocamento como proposta para a literatura deste milênio

Directory of Open Access Journals (Sweden)

Renato Cordeiro Gomes

2004-06-01

Full Text Available O escritor italiano Italo Calvino deixou como testamento literário seis propostas que caracterizariam a literatura do "próximo milênio", mas não teve tempo de redigir a sexta dessas propostas, justamente a "consistência". O escritor argentino Ricardo Piglia, na conferência "Três propostas para o próximo milênio (e cinco dificuldades", proferida na Casa de las Américas, Cuba, em 2000, propõe, então, escrevê-la, não a consistência, mas o "deslocamento, a distância", para equacionar o problema do futuro da literatura e sua função na sociedade, vista, entretanto, a partir da margem, das bordas das tradições centrais da América Hispânica.El escritor italiano Italo Calvino ha dejado como testigo literario seis propuestas para caracterizar la literatura del "próximo milenio", pero no tuvo tiempo de escribir la sexta, justo la que llevaria el nombre de "consistencia". El escritor argentino Ricardo Piglia en su conferencia "Tres propuestas para el próximo milenio (y cinco dificultades", hecha en la Casa de Las Américas, Cuba, año 2000, intenta escribirla - no como consistencia - sino como "desplazamiento, distancia", para equacionar el problema del futuro de la literatura y su función en la sociedad, pero desde el margen, desde el borde de las tradiciones centrales de Hispano-América.The Italan writer Italo Calvino has left as his literary legacy the six proposals that would characterize the literature of the "next millenium", but he had no time to write "consistency", the sixth of these proposals. The Argentinian writer Ricardo Piglia at the "Three proposals for the next millenium (and five difficulties", conference held at "Casa de las Américas", Cuba, in 2000, proposes, therefore, to write the proposals "dislocation" and "distance" in the place of consistency, aiming at solving the problem of literature's future and its role in society, which is seen, however, from the edge, from the border of Spanish America's central

Differences in the Processes of Solving Physics Problems between Good Physics Problem Solvers and Poor Physics Problem Solvers.

Science.gov (United States)

Finegold, M.; Mass, R.

1985-01-01

Good problem solvers and poor problem solvers in advanced physics (N=8) were significantly different in their ability in translating, planning, and physical reasoning, as well as in problem solving time; no differences in reliance on algebraic solutions and checking problems were noted. Implications for physics teaching are discussed. (DH)

synthesis, rheological behavior and swelling properties of ...

African Journals Online (AJOL)

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hydrogels obtained in long cylindrical shapes were cut into pieces of ... samples was determined at different temperature (25-70 °C) and removed from water at regular .... Lee, S.B.; Ha, D.I.; Cho, S.K.; Lee, Y.M.; Kim, S.J. J. Appl. Polym. Sci.

Screening and characterization a RAPD marker of tobacco brown ...

African Journals Online (AJOL)

STORAGESEVER

2008-08-04

Aug 4, 2008 ... Random amplified DNA polymorphism of Nicotiana tabacum L. cultivars. Biologia Plantarum. 49: 605-607. Zhang HY, Liu XZ, Li TS, Yang YM (2006). Genetic diversity among flue- cured tobacco (Nicotiana tabacum L.) revealed by amplified fragment length polymorphism. Botanical Studies. 47: 223-229.

Genetic characterization of fin fish species from the Warri River at ...

African Journals Online (AJOL)

SAM

2014-07-02

Jul 2, 2014 ... Genetic characterization of fin fish species from the. Warri River at Ubeji, Niger Delta, Nigeria. Asagbra ..... Prochilodus lineatus, Salminus brasiliensis and Steindachneridion scripta) from Uruguay River basin. Brazilian Archives Biol. Tech. 49(4):589-598. Saad YM, Shaden-Hanafi M, Essa MA, Guerges AA ...

Mechanism(s) of Electricity Production by Shewanella and other Microbes: Understanding and Optimization

Science.gov (United States)

2013-08-23

on to fruitful research careers because of the experience. Collaborations with other Institutions: 1. University of New Mexico – Atanassov’s MURI...Y., A. Obraztsova, G. Rosen, J. Leather , K.G. Scheckel, K.H. Nealson, and Y.M. Arias-Thode. 2011. Marine microbial community response to inorganic

Triterpenoid Saponins from Stauntonia chinensis

International Nuclear Information System (INIS)

Chen, Yu; Yang, Fang; Wang, Sha; Wang, Debin; Xu, Jing; Yang, Guangzhong

2014-01-01

The chemical constituents of S. chinensis were previously reported to contain nortriterpenoid saponins, neolignan glycosides, flavonoids. To find the biologically active compounds, a detailed phytochemical investigation was carried out on the stem of S. chinensis, which resulted in isolation of two new triterpenoid saponins, named as yemuo-side YM. Their structues were established on the basis of 2D-NMR experiments and mass spectrometry. In addition, eight known triterpene glycoside 3-O-α-L-arabinopyranosyl-30-norhederagenin, sinofoside A, yemuoside YM11, 3-O-α-L-arabinopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranos yl-akebonic acid, 3-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-hederagenin, 3-O-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin, hederasaponin D and 28-O-β-D-glucopyranosyl-(16)-β-D-glucopyranosyl-hederagenin were isolated from this plant. Compounds and were isolated from thisplant for the first time

Physico-functional and mechanical properties of chitosan and calcium salts incorporated fish gelatin scaffolds.

Science.gov (United States)

Jeevithan, E; Jeya Shakila, R; Varatharajakumar, A; Jeyasekaran, G; Sukumar, D

2013-09-01

Four types of fish gelatin scaffolds viz. gelatin (G), gelatin-chitosan (GC), gelatin-calcium acetate (GCA) and gelatin-chitosan-calcium acetate (GCCA) prepared were investigated for their functional properties, biomechanical strength, microstructural changes in relation to biodegradation. GC scaffold was superior with pH 3.15 and viscosity 9.40 cP. Chitosan and calcium acetate improved tensile strength (TS) and Young's modulus (YM), but lowered elongation at break (EAB). GCCA scaffold possessed moderate TS of 19.6 MPa, EAB of 4.76% and YM of 185 MPa. Foaming ability ratio of GC scaffold was high (3.41). GCA and GCCA scaffolds remained for 4 days before complete in vitro biodegradation. GC scaffold had larger cavities (180-300 μm) that were responsible for low swelling ratios and shrinkage factor. GCCA scaffold with moderate swelling rates, mechanical, functional properties and lowered biodegradation rate were found more suitable for biomedical applications. Copyright © 2013 Elsevier B.V. All rights reserved.

PMMA to SU-8 Bonding for Polymer Based Lab-on-a-chip Systems with Integrated Optics

DEFF Research Database (Denmark)

Olsen, Brian Bilenberg; Nielsen, Theodor; Nilsson, Daniel

2003-01-01

An adhesive bonding technique for wafer-level sealing of SU-8 based lab-on-a-chip microsystems with integrated optical components is presented. Microfluidic channels and optical components, e.g. waveguides, are fabricated in cross-linked SU-8 and sealed with a Pyrex glass substrate by means...... strength of 16 MPa is achieved at bonding temperatures between 110 oC and 120oC, at a bonding force of 2000 N on a 4-inch wafer. The optical propagation loss of multi-mode 10ym (thickness)x 30ym (width)SU-8 waveguides is measured. The propagation loss in PMMA bonded waveguide struc-tures is more than 5 d......B/cm lower, at wavelengths between 600nm and 900 nm, than in similar structures bonded by an intermediate layer of SU-8. Furthermore 950K PMMA shows no tendency to flow into the bonded structures during bonding because of its high viscosity....

Triterpenoid Saponins from Stauntonia chinensis

Energy Technology Data Exchange (ETDEWEB)

Chen, Yu [South Central Univ. for Nationalities, Wuhan (China); Yang, Fang; Wang, Sha; Wang, Debin; Xu, Jing; Yang, Guangzhong [South Central Univ. for Nationalities, Wuhan (China)

2014-04-15

The chemical constituents of S. chinensis were previously reported to contain nortriterpenoid saponins, neolignan glycosides, flavonoids. To find the biologically active compounds, a detailed phytochemical investigation was carried out on the stem of S. chinensis, which resulted in isolation of two new triterpenoid saponins, named as yemuo-side YM. Their structues were established on the basis of 2D-NMR experiments and mass spectrometry. In addition, eight known triterpene glycoside 3-O-α-L-arabinopyranosyl-30-norhederagenin, sinofoside A, yemuoside YM11, 3-O-α-L-arabinopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranos yl-akebonic acid, 3-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl-hederagenin, 3-O-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin, hederasaponin D and 28-O-β-D-glucopyranosyl-(16)-β-D-glucopyranosyl-hederagenin were isolated from this plant. Compounds and were isolated from thisplant for the first time.

Effects of aging on muscle mechanical function and muscle fiber morphology during short-term immobilization and subsequent retraining

DEFF Research Database (Denmark)

Hvid, Lars; Aagaard, Per; Justesen, Lene

2010-01-01

to the deleterious effects of short-term muscle disuse on muscle fiber size and rapid force capacity than YM. Furthermore, OM seems to require longer time to recover and regain rapid muscle force capacity, which may lead to a larger risk of falling in aged individuals after periods of short-term disuse.......Very little attention has been given to the combined effects of aging and disuse as separate factors causing deterioration in muscle mechanical function. Thus the purpose of this study was to investigate the effects of 2 wk of immobilization followed by 4 wk of retraining on knee extensor muscle...... mechanical function (e.g., maximal strength and rapid force capacity) and muscle fiber morphology in 9 old (OM: 67.3 ± 1.3 yr) and 11 young healthy men (YM: 24.4 ± 0.5 yr) with comparable levels of physical activity. Following immobilization, OM demonstrated markedly larger decreases in rapid force capacity...

More than a Facebook revolution: Social movements and social media in the Egyptian Arab Spring

Directory of Open Access Journals (Sweden)

Luis Fernando Barón

2015-06-01

Full Text Available Public opinion leaders and activists characterized the Egyptian “Arab Spring” of January 2011 as a “Facebook Revolution”. They highlight the intrinsic power of social media as an influencing factor for social change. Undeniably, social media played important roles in that revolution process. However, these roles cannot be disconnected from the socio-political contexts. This paper discusses the use of social media, particularly of Facebook, by the April 6th Youth Movement (A6YM, a decisive actor of the Egyptian protests. It is based on the analysis of two Egyptian newspapers and one American newspaper, between 2008 and 2011. We propose that a social media provided alternative mechanisms for political expression and organization, b social media contributed to the genesis and consolidation of the A6YM and to the establishment of youth political identities, and c the combination of “bits and streets” amplified not just the movement’s mobilization but the degree of opposition experienced by the Egyptian regime.

Using an isomorphic problem pair to learn introductory physics: Transferring from a two-step problem to a three-step problem

Directory of Open Access Journals (Sweden)

Shih-Yin Lin

2013-10-01

Full Text Available In this study, we examine introductory physics students’ ability to perform analogical reasoning between two isomorphic problems which employ the same underlying physics principles but have different surface features. 382 students from a calculus-based and an algebra-based introductory physics course were administered a quiz in the recitation in which they had to learn from a solved problem provided and take advantage of what they learned from it to solve another isomorphic problem (which we call the quiz problem. The solved problem provided has two subproblems while the quiz problem has three subproblems, which is known from previous research to be challenging for introductory students. In addition to the solved problem, students also received extra scaffolding supports that were intended to help them discern and exploit the underlying similarities of the isomorphic solved and quiz problems. The data analysis suggests that students had great difficulty in transferring what they learned from a two-step problem to a three-step problem. Although most students were able to learn from the solved problem to some extent with the scaffolding provided and invoke the relevant principles in the quiz problem, they were not necessarily able to apply the principles correctly. We also conducted think-aloud interviews with six introductory students in order to understand in depth the difficulties they had and explore strategies to provide better scaffolding. The interviews suggest that students often superficially mapped the principles employed in the solved problem to the quiz problem without necessarily understanding the governing conditions underlying each principle and examining the applicability of the principle in the new situation in an in-depth manner. Findings suggest that more scaffolding is needed to help students in transferring from a two-step problem to a three-step problem and applying the physics principles appropriately. We outline a few

Using an isomorphic problem pair to learn introductory physics: Transferring from a two-step problem to a three-step problem

Science.gov (United States)

Lin, Shih-Yin; Singh, Chandralekha

2013-12-01

In this study, we examine introductory physics students’ ability to perform analogical reasoning between two isomorphic problems which employ the same underlying physics principles but have different surface features. 382 students from a calculus-based and an algebra-based introductory physics course were administered a quiz in the recitation in which they had to learn from a solved problem provided and take advantage of what they learned from it to solve another isomorphic problem (which we call the quiz problem). The solved problem provided has two subproblems while the quiz problem has three subproblems, which is known from previous research to be challenging for introductory students. In addition to the solved problem, students also received extra scaffolding supports that were intended to help them discern and exploit the underlying similarities of the isomorphic solved and quiz problems. The data analysis suggests that students had great difficulty in transferring what they learned from a two-step problem to a three-step problem. Although most students were able to learn from the solved problem to some extent with the scaffolding provided and invoke the relevant principles in the quiz problem, they were not necessarily able to apply the principles correctly. We also conducted think-aloud interviews with six introductory students in order to understand in depth the difficulties they had and explore strategies to provide better scaffolding. The interviews suggest that students often superficially mapped the principles employed in the solved problem to the quiz problem without necessarily understanding the governing conditions underlying each principle and examining the applicability of the principle in the new situation in an in-depth manner. Findings suggest that more scaffolding is needed to help students in transferring from a two-step problem to a three-step problem and applying the physics principles appropriately. We outline a few possible strategies

"What constitutes a 'problem'?" Producing 'alcohol problems' through online counselling encounters.

Science.gov (United States)

Savic, Michael; Ferguson, Nyssa; Manning, Victoria; Bathish, Ramez; Lubman, Dan I

2017-08-01

Typically, health policy, practice and research views alcohol and other drug (AOD) 'problems' as objective things waiting to be detected, diagnosed and treated. However, this approach to policy development and treatment downplays the role of clinical practices, tools, discourses, and systems in shaping how AOD use is constituted as a 'problem'. For instance, people might present to AOD treatment with multiple psycho-social concerns, but usually only a singular AOD-associated 'problem' is considered serviceable. As the assumed nature of 'the serviceable problem' influences what treatment responses people receive, and how they may come to be enacted as 'addicted' or 'normal' subjects, it is important to subject clinical practices of problem formulation to critical analysis. Given that the reach of AOD treatment has expanded via the online medium, in this article we examine how 'problems' are produced in online alcohol counselling encounters involving people aged 55 and over. Drawing on poststructural approaches to problematisation, we not only trace how and what 'problems' are produced, but also what effects these give rise to. We discuss three approaches to problem formulation: (1) Addiction discourses at work; (2) Moving between concerns and alcohol 'problems'; (3) Making 'problems' complex and multiple. On the basis of this analysis, we argue that online AOD counselling does not just respond to pre-existing 'AOD problems'. Rather, through the social and clinical practices of formulation at work in clinical encounters, online counselling also produces them. Thus, given a different set of circumstances, practices and relations, 'problems' might be defined or emerge differently-perhaps not as 'problems' at all or perhaps as different kinds of concerns. We conclude by highlighting the need for a critical reflexivity in AOD treatment and policy in order to open up possibilities for different ways of engaging with, and responding to, people's needs in their complexity

How do open-ended problems promote mathematical creativity? A reflection of bare mathematics problem and contextual problem

Science.gov (United States)

Wijaya, A.

2018-03-01

Creativity is often seen as one of the fundamental aspects of character education. As one of the 21st century skills, creativity has also been considered as an important goal of education across the world. This paper reports a study on promoting mathematical creativity through the use of open-ended mathematics problems. A total of 53 undergraduate students participated in the study. These students worked on open-ended problems in two types, i.e. bare mathematics problem and contextual problem. The contextual problem was presented in the form of paper-based and Geogebra-based. The students’ works were analysed qualitatively in order to describe how students’ mathematical creativity developed. It was found that the open-ended problems successfully promote students’ creativity as indicated by various solutions or strategies that were used by students to solve the problems. The analysis of students’ works show that students’ creativity developed through three kinds of exploration, i. e. (1) exploration of contexts, (2) exploration of software features, and (3) exploration of mathematics concepts. The use of metacognitive questioning was found to be helpful to develop the first two explorations into mathematical exploration.

Diagnosing plant problems

Science.gov (United States)

Cheryl A. Smith

2008-01-01

Diagnosing Christmas tree problems can be a challenge, requiring a basic knowledge of plant culture and physiology, the effect of environmental influences on plant health, and the ability to identify the possible causes of plant problems. Developing a solution or remedy to the problem depends on a proper diagnosis, a process that requires recognition of a problem and...

General problems

International Nuclear Information System (INIS)

2005-01-01

This article presents the general problems as natural disasters, consequences of global climate change, public health, the danger of criminal actions, the availability to information about problems of environment

Trashing the millenium: Subjectivity and technology in cyberpunk science fiction

Directory of Open Access Journals (Sweden)

J. A. Sey

1992-05-01

Full Text Available 'Cyberpunk’ science fiction is a self-proclaimed movement within the genre which began in the 1980s. As the name suggests, it is an extrapolative form of science fiction which combines an almost obsessional interest in machines (particularly information machines with an anarchic, amoral, streetwise sensibility This paper sketches the development of the movement and seeks to make qualified claims for the radical. potential of its fiction. Of crucial importance are the ways in which human subjectivity (viewed in psychoanalytic terms interacts with 'technological subjectivity' in cyberpunk, particularly with regard to implications of these interactions for oedipalization.

Water operator partnerships as a model to achieve the Millenium ...

African Journals Online (AJOL)

2010-08-17

Aug 17, 2010 ... Department of Management and Institutions, UNESCO-IHE Institute for Water Education, PO Box ..... FIPAG and Vitens signed a Letter of Intent in July of 2003 ... resources costs, some goods and services, and audit costs.

DAYLIGHTING AND ENERGY PERFORMANCE OF POST MILLENIUM CONDOMINIUMS IN SINGAPORE

Directory of Open Access Journals (Sweden)

Uma Maheswaran

2007-03-01

habitable spaces in their residence. This paper is an attempt to discuss a few examples of condominiums around the western part of Singapore as a means of discussing the emerging design trends as well as to discuss the performance aspects of the design solutions in terms of day lighting and energy consumption.

Water operator partnerships as a model to achieve the Millenium ...

African Journals Online (AJOL)

In the void left by the declining popularity of public-private partnerships, the concept of 'water operator partnerships' (WOPs) has increasingly been promoted as an alternative for improving water services provision in developing countries. This paper assesses the potential of such partnerships as a 'model' for contributing to ...

The book of SCSI I/O for the new millenium

CERN Document Server

Field, Gary

2000-01-01

This second edition of The Book of SCSI provides down-to-earth instructions for installing, implementing, utilizing, and maintaining SCSI on a PC. Accessible to readers at all levels, this is the standard reference for anyone working with or maintaining a SCSI system. Along with complete coverage of SCSI-3 and all the latest features, The Book of SCSI: I/O for the New Millennium contains many new and updated features. What's New? New and expanded sections on ASPI programming including a sample utility program A new chapter on SCSI device drivers A CD-ROM with SCSI diagnostic tools and utilities, a searchable copy of the book for quick referencing and the SCSI FAQ, SCSI Quick Start Guide, and SCSI Game Rules Coverage of Ultra2/LVD (Low Voltage Differential), Fibre Channel, RAID, DVD, and more New directions in the SCSI and storage industry A chapter on SCSI test equipment Many new drawings and diagrams of the multitude of SCSI connectors A comprehensive troubleshooting guide What Hasn't Changed Plain English e...

Microscale Experiments in Chemistry - The Need of the New Millenium

Indian Academy of Sciences (India)

adsorption, partition coefficient, measurement of viscosity, sta- ... the next step to estimate the concentration of iodine in aqueous ... separation of the layers, iodine in each layer is estimated by titration. .... Expensive metals in thin wire form are soldered to copper .... ions, cobalt and nickel, is attempted by this technique. The.

The Caspian Sea geopolitical game: prospects for the new millenium

International Nuclear Information System (INIS)

Bahgat, G.

1999-01-01

The break-up of the Soviet Union in the early 1990s opened the door for the international oil companies to explore and develop the Caspian Sea's hydrocarbon resources. The full utilisation of this wealth, however, has been hindered by disagreement over the ownership of the basin and the choice of export routes. In addition, there is no consensus on the exact quantity of resources there. This study examines all these issues and focuses on the rivalry between a regional power - the Islamic Republic of Iran - and an international one - the United States of America. The contention is that they have a mutual interest in promoting economic development and political stability in the Caspian region

Transportation 2000. Spent fuel transportation trends in the new millenium

International Nuclear Information System (INIS)

Blee, David; Viebrock, James; Patterson, John

1999-01-01

The paper will provide a comparison of foreign research reactor spent fuel transportation today verses the assumptions used by the Department of Energy in the Environmental Impact Statement. In addition, it will suggest changes that are likely to occur in transportation logistics through the remainder of the U.S. spent fuel returns program. Cask availability, certification status, shipment strategy, cost issues, and public acceptance are among the topical areas that will be examined. Transportation requirements will be assessed in light of current participation in the returns program and the tendency for shipment plans to shift toward spent fuel return toward the end of the 13 year period of eligibility. (author)

Energy use in the new millenium. Trends in IEA countries

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-09-10

At their Gleneagles Summit in July 2005, G8 leaders identified climate change and securing clean energy and sustainable development as key global challenges. They agreed that we must transform the way we use energy and that we must start now. Improved energy efficiency is essential to meeting this goal. Therefore, the G8 asked the IEA to provide analysis of energy use and efficiency developments in buildings, appliances, transport and industry. This publication is a response to the G8 request. Looking back, it shows how changes in energy efficiency, economic structure, income, prices and fuel mix have affected recent trends in energy use and CO2 emissions in IEA countries. The results are a 'wake-up call' for us all. Since 1990, the rate of energy efficiency improvement in IEA countries has been less than 1% per year - much lower than in previous decades and not nearly enough to stem the growth of CO2 emissions. If we are to tackle climate change and move towards a sustainable energy future then this rate will need to double. We must - and we can - do better. By means of in-depth energy indicators, this publication provides important insights to policy-makers about current energy use and CO2 emission patterns that will help shape priorities for future action.

Will silicon be the photonic material of the third millenium?

International Nuclear Information System (INIS)

Pavesi, L

2003-01-01

Silicon microphotonics, a technology which merges photonics and silicon microelectronic components, is rapidly evolving. Many different fields of application are emerging: transceiver modules for optical communication systems, optical bus systems for ULSI circuits, I/O stages for SOC, displays, .... In this review I will give a brief motivation for silicon microphotonics and try to give the state-of-the-art of this technology. The ingredient still lacking is the silicon laser: a review of the various approaches will be presented. Finally, I will try to draw some conclusions where silicon is predicted to be the material to achieve a full integration of electronic and optical devices. (topical review)

Microscale Experiments in Chemistry - The Need of the New Millenium

Indian Academy of Sciences (India)

Chemistry at University of Pune. ... scribes the use of about 0.2 g chemical for every test of the qualitative .... With reduction in amounts and time, the students can now do ... The indicator is set free and the colour of the complex changes.

Teaching Problem Solving without Modeling through "Thinking Aloud Pair Problem Solving."

Science.gov (United States)

Pestel, Beverly C.

1993-01-01

Reviews research relevant to the problem of unsatisfactory student problem-solving abilities and suggests a teaching strategy that addresses the issue. Author explains how she uses teaching aloud problem solving (TAPS) in college chemistry and presents evaluation data. Among the findings are that the TAPS class got fewer problems completely right,…

Kolkata Restaurant Problem as a Generalised El Farol Bar Problem

Science.gov (United States)

Chakrabarti, Bikas K.

Generalisation of the El Farol bar problem to that of many bars here leads to the Kolkata restaurant problem, where the decision to go to any restaurant or not is much simpler (depending on the previous experience of course, as in the El Farol bar problem). This generalised problem can be exactly analysed in some limiting cases discussed here. The fluctuation in the restaurant service can be shown to have precisely an inverse cubic behavior, as widely seen in the stock market fluctuations.

Matrix interdiction problem

Energy Technology Data Exchange (ETDEWEB)

Pan, Feng [Los Alamos National Laboratory; Kasiviswanathan, Shiva [Los Alamos National Laboratory

2010-01-01

In the matrix interdiction problem, a real-valued matrix and an integer k is given. The objective is to remove k columns such that the sum over all rows of the maximum entry in each row is minimized. This combinatorial problem is closely related to bipartite network interdiction problem which can be applied to prioritize the border checkpoints in order to minimize the probability that an adversary can successfully cross the border. After introducing the matrix interdiction problem, we will prove the problem is NP-hard, and even NP-hard to approximate with an additive n{gamma} factor for a fixed constant {gamma}. We also present an algorithm for this problem that achieves a factor of (n-k) mUltiplicative approximation ratio.

Comparison of hyperpronation and supination‑flexion techniques in ...

African Journals Online (AJOL)

2013-07-24

Jul 24, 2013 ... Green DA, Linares YM, Garcia Pena MB, Greenberg M, Baker RL: Randomized comparison of pain perception during radial head subluxation using supination‑ flexion or forced pronation. Pediatr Emerg Care 2006;22:235‑8. 8. McDonald LJ, Whitelaw C, Goldsmith L. Radial head subluxation: Comparing.

27 CFR 447.21 - The U.S. Munitions Import List.

Science.gov (United States)

2010-04-01

... (Mustard Gas, HD or H). (3) Ethyldichloroarsine (ED). (4) Methyldichloroarsine (MD). (c) Lachrymators and..., YFRT, YHLC, YM, YNG, YP, YPD, YR, YRB, YRBN, YRDH, YRDM, YRR, YRST, YSD). (e) Coast Guard Patrol and..., including but not limited to lung irritants, vesicants, lachrymators, and tear gases (except tear gas...

Circulating microRNAs as diagnostic biomarkers for cardiovascular diseases

NARCIS (Netherlands)

Tijsen, Anke J.; Pinto, Yigal M.; Creemers, Esther E.

2012-01-01

Tijsen AJ, Pinto YM, Creemers EE. Circulating microRNAs as diagnostic biomarkers for cardiovascular diseases. Am J Physiol Heart Circ Physiol 303: H1085-H1095, 2012. First published August 31, 2012; doi:10.1152/ajpheart.00191.2012.-One of the major challenges in cardiovascular disease is the

77 FR 6804 - Advisory Committee for Reproductive Health Drugs; Notice of Meeting

Science.gov (United States)

2012-02-09

... symptoms of urge urinary incontinence, urgency, and urinary frequency. Mirabegron is a beta-3- adrenoceptor (AR) agonist and is a new molecular entity. The benefit/ risk discussion will focus on the adequacy of... benefits and risks of mirabegron (YM178), under new drug application (NDA) 202611, submitted by Astellas...

Biosorption characteristics of Aspergillus fumigatus in removal of ...

African Journals Online (AJOL)

STORAGESEVER

2009-09-01

Sep 1, 2009 ... in growth medium, thus about 20% of the isolates can grow up to 50 mg Cd/100 ml medium and only ... have the highest Cd biosorption, compared to yeast malt extract (YM) and sabourad (Sb) media. ... chemical parameters of the solution, say, temperature, ...... inactivated Phanerochaete chrysosporium.

77 FR 56638 - Combined Notice of Filings #1

Science.gov (United States)

2012-09-13

.... Applicants: New York Independent System Operator, Inc. Description: Amendment to NYISO OATT, Attachment Y....m. e.t. 9/17/12. Docket Numbers: ER12-2368-000. Applicants: Denver City Energy Associates, LP... Denver City Energy Associates, L.P. tariff. Filed Date: 9/5/12. Accession Number: 20120905-5122. Comments...

Islamic Education Research Problem

Directory of Open Access Journals (Sweden)

Abdul Muthalib

2012-04-01

Full Text Available This paper will discuss Islamic educational studies that is reviewing how to find, limit and define problems and problem-solving concepts. The central question of this paper is to describe how to solve the problem in Islamic educational research. A researcher or educator who has the knowledge, expertise, or special interest on education for example is usually having a sensitivity to issues relating to educational research. In the research dimension of religious education, there are three types of problems, namely: Problems foundation, structural problems and operational issues. In doing research in Islamic education someone should understand research problem, limiting and formulating the problem, how to solve the problem, other problem relating to the point of research, and research approach.

The Chicken Problem.

Science.gov (United States)

Reeves, Charles A.

2000-01-01

Uses the chicken problem for sixth grade students to scratch the surface of systems of equations using intuitive approaches. Provides students responses to the problem and suggests similar problems for extensions. (ASK)

YM on the dielectric brane: a D0-brane tale

International Nuclear Information System (INIS)

Martucci, Luca; Silva, Pedro J.

2003-01-01

In this letter we present a derivation, from the D0-brane picture, of the background monopole field and in general of the full dynamics of the Yang-Mills theory on the dielectric D2-brane of Myers. To do this we study the large N limit of the fuzzy sphere relevant to the dielectric solution. In contrast to the usual interpretation where the commutative D2-brane picture arises directly from the large N limit of the D0-brane picture, we find that a residual non-commutativity must be preserved in order to make the connection by means of the Seiberg-Witten map

Analysis of Maceaene and Macamide Contents of Petroleum Ether Extract of Black, Yellow, and Purple Lepidium Meyenii (Maca and Their Antioxidant Effect on Diabetes Mellitus Rat Model

Directory of Open Access Journals (Sweden)

Congyang Qiu

Full Text Available ABSTRACT Maceaene and macamide contents as well as antioxidant effect of petroleum ether extract of black maca (BM, yellow maca (YM, and purple maca (PM on diabetes mellitus (DM rats were investigated. The results showed that seven, six, and five analogues of macamides were identified from the petroleum ether extracts of BM, YM, and PM, respectively. BM extract exhibited the highest contents of total macamides. Comparatively, the PM extract has the lowest macamide quantity. The maceaene contents in all the extracts showed no significant difference (p>0.05. Macamide contents in maca with the same color were not statistically different. Pharmacological results showed that 60-day oral administration of the petroleum ether extract of maca (100 mg/kg.d can significantly decrease lipid oxidation as indicated by the decreased thiobarbituric acid reactive substances (TBARS and carbonylated proteins (CP concentrations on DM rat model (P<0.05. Among them, oral administration of PM extract showed the lowest TBRAS and CP concentrations. All maca extracts can enhance antioxidant enzyme (SOD, superoxide dismutase; CAT, catalase activity of liver and red blood cells (RBC of DM rat. However, only oral administration of PM extract can increase SOD and CAT activity of both RBC and liver. The glutathion (GSH contents in plasma were significantly increased in DM rats treated with PM extract (p<0.05. But, oral administration of BM and YM extracts did not enhance GSH levels. Take together, the data suggested that PM extract exhibited the most potent antioxidant activity on DM rat model. And, maceaene and macamide in maca extract was not correlated with its antioxidant ability.

Estimation of spatial distribution of recharge factors at Yucca Mountain, Nevada

International Nuclear Information System (INIS)

Stothoff, S.A.; Bagtzoglou, A.C.; Castellaw, H.

1995-01-01

Determining compliance with the performance objectives for both the repository system and the Geologic Setting (GS) requires prediction of groundwater flow. Since infiltration is the primary source of water in the subsurface, the amounts and locations of infiltration are controlling factors in the movement of groundwater throughout the GS. In fractured, unsaturated rock, such as that found at the Yucca Mountain (YM) site, occurrence of infrequent, high-intensity rainfall events will modify, perhaps drastically, the subsurface flow regime from the one predicted by assuming that all rainfall events have averaged intensities. Indeed, the DOW has concluded that the spatial and temporal distribution of infiltration may be the most important factors influencing groundwater flow path development. Deep percolation fluxes are affected by processes active in the near-surface zone, including evaporation, transpiration, liquid water flow, and vapor flow. Each of these processes is governed by several factors. For example, precipitation has been found to vary substantially over the YM region, both spatially and temporally, and winter storms are, in general, more uniform and of longer duration than summer storms (Hevesi et al., 1992a,b; 1994). These observations indicate that, especially for summer storms, a spatially uniform precipitation pattern is clearly not applicable, even at the subregional scale. Similarly, evaporation from the ground surface is affected by air temperature, atmospheric vapor pressure, wind speed profile, incident solar radiation, surface soil and rock texture, plant activity, surficial temperature, and surficial moisture content. Many of these factors, such as surficial slope and orientation (related to incident solar radiation), surficial composition, and plant distributions, are or can be mapped at the YM site

Ankle Problems

Science.gov (United States)

... Read MoreDepression in Children and TeensRead MoreBMI Calculator Ankle ProblemsFollow this chart for more information about problems that can cause ankle pain. Our trusted Symptom Checker is written and ...

Serie 2, no. 4, EN: September de 2017

OpenAIRE

Millenium, Millenium

2017-01-01

Millenium journal reaches the end of the first year of series 2, with this number 4. September 2017 marks the effort of a new editorial policy that is translated into the publication of four numbers with articles simultaneously in Portuguese andEnglish, whose scientific quality was rigorously attested by blind peer review and whose authors are external to the IPV.Two more issues were also published as Special Edition. This issue maintains the objective of a multidisciplinary and transdiscipli...

Preventing Diabetes Problems

Science.gov (United States)

... Problems Diabetes, Sexual, & Bladder Problems Clinical Trials Preventing Diabetes Problems View or Print All Sections Heart Disease & ... to help control symptoms and restore intimacy. Depression & Diabetes Depression is common among people with a chronic, ...

Prostate Problems

Science.gov (United States)

... know the exact cause of your prostate problem. Prostatitis The cause of prostatitis depends on whether you ... prostate problem in men older than age 50. Prostatitis If you have a UTI, you may be ...

Radioactive wastes: a world problem. Les dechets nucleaires: un probleme mondial

Energy Technology Data Exchange (ETDEWEB)

Schapira, J P [Centre National de la Recherche Scientifique (CNRS), 75 - Paris (FR)

1991-02-01

In all countries endowed with nuclear program, radioactive wastes disposal asks scientific and public acceptance problems. This paper describes several aspects: technical problem; ethic problem and responsibility towards future generations at very long-term; political problem. Different politics followed by concerned countries and recent controversy in France is also entered upon radioactive wastes underground site selection, in deep geological formations.

Popular Problems

DEFF Research Database (Denmark)

Skovhus, Randi Boelskifte; Thomsen, Rie

2017-01-01

This article introduces a method to critical reviews and explores the ways in which problems have been formulated in knowledge production on career guidance in Denmark over a 10-year period from 2004 to 2014. The method draws upon the work of Bacchi focussing on the ‘What's the problem represented...... to be’ (WPR) approach. Forty-nine empirical studies on Danish youth career guidance were included in the study. An analysis of the issues in focus resulted in nine problem categories. One of these, ‘targeting’, is analysed using the WPR approach. Finally, the article concludes that the WPR approach...... provides a constructive basis for a critical analysis and discussion of the collective empirical knowledge production on career guidance, stimulating awareness of problems and potential solutions among the career guidance community....

Case Problems for Problem-Based Pedagogical Approaches: A Comparative Analysis

Science.gov (United States)

Dabbagh, Nada; Dass, Susan

2013-01-01

A comparative analysis of 51 case problems used in five problem-based pedagogical models was conducted to examine whether there are differences in their characteristics and the implications of such differences on the selection and generation of ill-structured case problems. The five pedagogical models were: situated learning, goal-based scenario,…

The effect of problem-based and lecture-based instructional strategies on learner problem solving performance, problem solving processes, and attitudes

Science.gov (United States)

Visser, Yusra Laila

This study compared the effect of lecture-based instruction to that of problem-based instruction on learner performance (on near-transfer and far-transfer problems), problem solving processes (reasoning strategy usage and reasoning efficiency), and attitudes (overall motivation and learner confidence) in a Genetics course. The study also analyzed the effect of self-regulatory skills and prior-academic achievement on performance for both instructional strategies. Sixty 11th grade students at a public math and science academy were assigned to either a lecture-based instructional strategy or a problem-based instructional strategy. Both treatment groups received 18 weeks of Genetics instruction through the assigned instructional strategy. In terms of problem solving performance, results revealed that the lecture-based group performed significantly better on near-transfer post-test problems. The problem-based group performed significantly better on far-transfer post-test problems. In addition, results indicated the learners in the lecture-based instructional treatment were significantly more likely to employ data-driven reasoning in the solving of problems, whereas learners in the problem-based instructional treatment were significantly more likely to employ hypothesis-driven reasoning in problem solving. No significant differences in reasoning efficiency were uncovered between treatment groups. Preliminary analysis of the motivation data suggested that there were no significant differences in motivation between treatment groups. However, a post-research exploratory analysis suggests that overall motivation was significantly higher in the lecture-based instructional treatment than in the problem-based instructional treatment. Learner confidence was significantly higher in the lecture-based group than in the problem-based group. A significant positive correlation was detected between self-regulatory skills scores and problem solving performance scores in the problem

Problem Posing

OpenAIRE

Šilhavá, Marie

2009-01-01

This diploma thesis concentrates on problem posing from the students' point of view. Problem posing can be either seen as a teaching method which can be used in the class, or it can be used as a tool for researchers or teachers to assess the level of students' understanding of the topic. In my research, I compare three classes, one mathematics specialist class and two generalist classes, in their ability of problem posing. As an assessment tool it seemed that mathemathics specialists were abl...

Learning Problems

Science.gov (United States)

... Staying Safe Videos for Educators Search English Español Learning Problems KidsHealth / For Kids / Learning Problems What's in ... for how to make it better. What Are Learning Disabilities? Learning disabilities aren't contagious, but they ...

A Specific Long-Term Plan for Management of U.S. Nuclear Spent Fuel

International Nuclear Information System (INIS)

Levy, Salomon

2006-01-01

A specific plan consisting of six different steps is proposed to accelerate and improve the long-term management of U.S. Light Water Reactor (LWR) spent nuclear fuel. The first step is to construct additional, centralized, engineered (dry cask) spent fuel facilities to have a backup solution to Yucca Mountain (YM) delays or lack of capacity. The second step is to restart the development of the Integral Fast Reactor (IFR), in a burner mode, because of its inherent safety characteristics and its extensive past development in contrast to Acceleration Driven Systems (ADS). The IFR and an improved non-proliferation version of its pyro-processing technology can burn the plutonium (Pu) and minor actinides (MA) obtained by reprocessing LWR spent fuel. The remaining IFR and LWR fission products will be treated for storage at YM. The radiotoxicity of that high level waste (HLW) will fall below that of natural uranium in less than one thousand years. Due to anticipated increased capital, maintenance, and research costs for IFR, the third step is to reduce the required number of IFRs and their potential delays by implementing multiple recycles of Pu and Neptunium (Np) MA in LWR. That strategy is to use an advanced separation process, UREX+, and the MIX Pu option where the role and degradation of Pu is limited by uranium enrichment. UREX+ will decrease proliferation risks by avoiding Pu separation while the MIX fuel will lead to an equilibrium fuel recycle mode in LWR which will reduce U. S. Pu inventory and deliver much smaller volumes of less radioactive HLW to YM. In both steps two and three, Research and Development (R and D) is to emphasize the demonstration of multiple fuel reprocessing and fabrication, while improving HLW treatment, increasing proliferation resistance, and reducing losses of fissile material. The fourth step is to license and construct YM because it is needed for the disposal of defense wastes and the HLW to be generated under the proposed plan. The

Hearing Problems

Science.gov (United States)

... Read MoreDepression in Children and TeensRead MoreBMI Calculator Hearing ProblemsLoss in the ability to hear or discriminate ... This flow chart will help direct you if hearing loss is a problem for you or a ...

ADSORPTION OF ACID DYE ONTO ACTIVATED ALGERIAN CLAY ...

African Journals Online (AJOL)

In this work, activated clay from Algeria was used as adsorbent for the ... paper, cosmetics, printing, and plastics are one of the major sources of water pollution. These ..... Mohammadi, S.Z.; Shamspur, T.; Baghelani, Y.M. Combination of flame atomic absorption ... and determination of trace amount of lead in water samples.

A Study of the Vertical Component of Ocean Floor Vibrations in Two Geographical Chokepoints

Science.gov (United States)

2017-05-30

30  4.  RSAC.m ............................................................................. 31  5.  MATLAB Data Analysis...75  5.  OBS Requests ................................................................... 75  APPENDIX A. MATLAB CODE...2008, 24 Hours, Frequency Limits of .01-.02-10-20 Hz. Source: [28]. ....................................... 36  Figure 26.  MATLAB Plot of YM 39 on June

Biocatalytic Enantioselective Synthesis of N-Substituted Aspartic Acids by Aspartate Ammonia Lyase

NARCIS (Netherlands)

Weiner, Barbara; Poelarends, Gerrit J.; Janssen, Dick B.; Feringa, Ben L.

2008-01-01

The gene encoding aspartate ammonia lyase (aspB) from Bacillus sp. YM55-1 has been cloned and overexpressed, and the recombinant enzyme containing a C-terminal His6 tag has been purified to homogeneity and subjected to kinetic characterization. Kinetic studies have shown that the His6 tag does not

Download this PDF file

African Journals Online (AJOL)

Arzu

Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.). J. Ethnopharmacol. 90: 205-215. 15. Hao, G., Yuan, Y.M., Hu, C.M., Ge, X.J. and Zhao, N.X. (2004). Molecular phylogeny of Lysimachia (Myrsinaceae) based on chloroplast. trnL-F and nuclear ribosomal ITS sequences. Mol. Phylogenet.

Editorial

Directory of Open Access Journals (Sweden)

Maria de Jesus Fonseca

2016-02-01

Full Text Available Celebra-se este ano o 15º aniversário de Millenium. A revista, enquanto publicação periódica do Instituto Politécnico de Viseu (IPV, lança o seu 1º número em Fevereiro de 1996 e, desde então até ao presente, tem cumprido com aquela que tem sido a sua periodicidade ao longo dos anos. Esta regularidade e continuidade editoriais que a revista tem conseguido manter ao longo destes 15 anos não é coisa de pouca monta, como bem o sabem os editores de publicações periódicas. Mas é essa regularidade que mantém viva uma publicação deste tipo, dando-lhe consistência e conferindo-lhe credibilidade. Assim, a publicação dos seus sucessivos números, de forma contínua e ininterrupta e em tempo oportuno, tem dado corpo e configurado a identidade de Millenium, assegurando-lhe a fidelidade e a confiança dos seus leitores habituais, garantindo-lhe um espaço próprio e permitindo o seu crescimento junto do público que a procura. Para isso muito contribuiu e continua a contribuir a sua disponibilização on-line em acesso livre, iniciada em 1997, e consumada em 1998 com a colocação on-line da versão integral e completa de cada número da revista.

Assessment of vertical transfer in problem solving: Mapping the problem design space

Science.gov (United States)

Von Korff, Joshua; Hu, Dehui; Rebello, N. Sanjay

2012-02-01

In schema-based theories of cognition, vertical transfer occurs when a learner constructs a new schema to solve a transfer task or chooses between several possible schemas. Vertical transfer is interesting to study, but difficult to measure. Did the student solve the problem using the desired schema or by an alternative method? Perhaps the problem cued the student to use certain resources without knowing why? In this paper, we consider some of the threats to validity in problem design. We provide a theoretical framework to explain the challenges faced in designing vertical transfer problems, and we contrast these challenges with horizontal transfer problem design. We have developed this framework from a set of problems that we tested on introductory mechanics students, and we illustrate the framework using one of the problems.

Problem Solving Reasoning and Problem Based Instruction in Geometry Learning

Science.gov (United States)

Sulistyowati, F.; Budiyono, B.; Slamet, I.

2017-09-01

This research aims to analyze the comparison Problem Solving Reasoning (PSR) and Problem Based Instruction (PBI) on problem solving and mathematical communication abilities viewed from Self-Regulated Learning (SRL). Learning was given to grade 8th junior high school students. This research uses quasi experimental method, and then with descriptive analysis. Data were analyzed using two-ways multivariate analysis of variance (MANOVA) and one-way analysis of variance (ANOVA) with different cells. The result of data analysis were learning model gives different effect, level of SRL gives the same effect, and there is no interaction between the learning model with the SRL on the problem solving and mathematical communication abilities. The t-test statistic was used to find out more effective learning model. Based on the test, regardless of the level of SRL, PSR is more effective than PBI for problemsolving ability. The result of descriptive analysis was PSR had the advantage in creating learning that optimizing the ability of learners in reasoning to solve a mathematical problem. Consequently, the PSR is the right learning model to be applied in the classroom to improve problem solving ability of learners.

Early breastfeeding problems

DEFF Research Database (Denmark)

Feenstra, Maria Monberg; Kirkeby, Mette Jørgine; Thygesen, Marianne

2018-01-01

Objectives Breastfeeding problems are common and associated with early cessation. Stilllength of postpartum hospital stay has been reduced. This leaves new mothers to establish breastfeeding at home with less support from health care professionals. The objective was to explore mothers’ perspectives...... on when breastfeeding problems were the most challenging and prominent early postnatal. The aim was also toidentify possible factors associated with the breastfeeding problems. Methods In a cross-sectional study, a mixed method approach was used to analyse postal survey data from 1437 mothers with full...... term singleton infants. Content analysis was used to analyse mothers’ open text descriptions of their most challenging breastfeeding problem. Multiple logistic regression was used to calculate odds ratios for early breastfeeding problems according to sociodemographic- and psychosocial factors. Results...

Investigation of Problem-Solving and Problem-Posing Abilities of Seventh-Grade Students

Science.gov (United States)

Arikan, Elif Esra; Ünal, Hasan

2015-01-01

This study aims to examine the effect of multiple problem-solving skills on the problem-posing abilities of gifted and non-gifted students and to assess whether the possession of such skills can predict giftedness or affect problem-posing abilities. Participants' metaphorical images of problem posing were also explored. Participants were 20 gifted…

Mathematical Tasks without Words and Word Problems: Perceptions of Reluctant Problem Solvers

Science.gov (United States)

Holbert, Sydney Margaret

2013-01-01

This qualitative research study used a multiple, holistic case study approach (Yin, 2009) to explore the perceptions of reluctant problem solvers related to mathematical tasks without words and word problems. Participants were given a choice of working a mathematical task without words or a word problem during four problem-solving sessions. Data…

Mathematical conversations multicolor problems, problems in the theory of numbers, and random walks

CERN Document Server

Dynkin, E B

2006-01-01

Comprises Multicolor Problems, dealing with map-coloring problems; Problems in the Theory of Numbers, an elementary introduction to algebraic number theory; Random Walks, addressing basic problems in probability theory. 1963 edition.

Cosmological constant problem

International Nuclear Information System (INIS)

Weinberg, S.

1989-01-01

Cosmological constant problem is discussed. History of the problem is briefly considered. Five different approaches to solution of the problem are described: supersymmetry, supergravity, superstring; anthropic approach; mechamism of lagrangian alignment; modification of gravitation theory and quantum cosmology. It is noted that approach, based on quantum cosmology is the most promising one

Dynamic Protocol Reverse Engineering: A Grammatical Inference Approach

Science.gov (United States)

2008-03-01

domain-specific languages”. OOPSLA ’05: Companion to the 20th annual ACM SIGPLAN conference on Object-oriented programming, systems, languages, and...Representation to k-TSS Lan- guage Models”. Computación y Sistemas , 3(4):273–244, 2000. ISSN 1405-5546. 256. Trakhtenbrot, B.A. and Y.M. Barzdin. Finite

Bioreactor activated graft material for early implant fixation in bone

DEFF Research Database (Denmark)

Snoek Henriksen, Susan; Ding, Ming; Overgaard, Søren

2011-01-01

from the iliac crest. For both groups, mononuclear cells were isolated, and injected into a perfusion bioreactor (Millenium Biologix AG, Switzerland). Scaffold granules (Ø~900-1500 µm, ~88% porosity) in group 1, consisted of hydroxyapatite (HA, 70%) with β-tricalcium-phosphate (β-TCP, 30%) (Danish....... The superficial part was used for mechanical testing and micro-CT scanning, and the profound part for histomorphometry. Push-out tests were performed on an 858 Bionix MTS hydraulic materials testing machine (MTS Systems Corporation, USA). Shear mechanical properties between implant and newly generated bone were...

Severská detektivka: Mezi kriminálním románem, společenskou kritikou a thrillerem

OpenAIRE

Danielková, Pavla

2017-01-01

The thesis presented here with deals with an analysis and genre definition of the Nordic detective story, which is currently very popular in the Czech Republic. It is namely an interpretation of the works done by two contemporary Nordic authors in question, i.e. Stieg Larsson and Jo Nesbø. With the first of the two authors I will be looking into the complete trilogy The Millenium containing volumes of Män som hatar kvinnor (2005), Flickan som lekte med elden (2006) and Luftslottet som sprängd...

The Neo-Victorian Novel, 1990-2010

OpenAIRE

Worthington, Julia

2013-01-01

The final decade of the twentieth century and the first decade of the twenty-first witnessed a surge of published novels with direct and indirect connection to the Victorian era, at a time when a focus on the new millenium might have been expected. This proliferation of what came to be termed 'neo-Victorian novels' shows no sign of abating and has now given rise to scholarly research on the subject. The principal aim of this thesis is to examine the rise of the neo-Victorian novel during ...

Differential equations problem solver

CERN Document Server

Arterburn, David R

2012-01-01

REA's Problem Solvers is a series of useful, practical, and informative study guides. Each title in the series is complete step-by-step solution guide. The Differential Equations Problem Solver enables students to solve difficult problems by showing them step-by-step solutions to Differential Equations problems. The Problem Solvers cover material ranging from the elementary to the advanced and make excellent review books and textbook companions. They're perfect for undergraduate and graduate studies.The Differential Equations Problem Solver is the perfect resource for any class, any exam, and

Problem-formulation and problem-solving in self-organized communities

DEFF Research Database (Denmark)

Foss, Nicolai J.; Frederiksen, Lars; Rullani, Francesco

2016-01-01

Building on the problem-solving perspective, we study behaviors related to projects and the communication-based antecedents of such behaviors in the free open-source software (FOSS) community. We examine two kinds of problem/project-behaviors: Individuals can set up projects around the formulation...

Inverse feasibility problems of the inverse maximum flow problems

Indian Academy of Sciences (India)

199–209. c Indian Academy of Sciences. Inverse feasibility problems of the inverse maximum flow problems. ADRIAN DEACONU. ∗ and ELEONOR CIUREA. Department of Mathematics and Computer Science, Faculty of Mathematics and Informatics, Transilvania University of Brasov, Brasov, Iuliu Maniu st. 50,. Romania.

[Population problem, comprehension problem].

Science.gov (United States)

Tallon, F

1993-08-01

Overpopulation of developing countries in general, and Rwanda in particular, is not just their problem but a problem for developed countries as well. Rapid population growth is a key factor in the increase of poverty in sub-Saharan Africa. Population growth outstrips food production. Africa receives more and more foreign food, economic, and family planning aid each year. The Government of Rwanda encourages reduced population growth. Some people criticize it, but this criticism results in mortality and suffering. One must combat this ignorance, but attitudes change slowly. Some of these same people find the government's acceptance of family planning an invasion of their privacy. Others complain that rich countries do not have campaigns to reduce births, so why should Rwanda do so? The rate of schooling does not increase in Africa, even though the number of children in school increases, because of rapid population growth. Education is key to improvements in Africa's socioeconomic growth. Thus, Africa, is underpopulated in terms of potentiality but overpopulated in terms of reality, current conditions, and possibilities of overexploitation. Africa needs to invest in human resources. Families need to save, and to so, they must refrain from having many children. Africa should resist the temptation to waste, as rich countries do, and denounce it. Africa needs to become more independent of these countries, but structural adjustment plans, growing debt, and rapid population growth limit national independence. Food aid is a means for developed countries to dominate developing countries. Modernization through foreign aid has had some positive effects on developing countries (e.g., improved hygiene, mortality reduction), but these also sparked rapid population growth. Rwandan society is no longer traditional, but it is also not yet modern. A change in mentality to fewer births, better quality of life for living infants, better education, and less burden for women must occur

The internal percolation problem

International Nuclear Information System (INIS)

Bezsudnov, I.V.; Snarskii, A.A.

2010-01-01

The internal percolation problem (IP) as a new type of the percolation problem is introduced and investigated. In spite of the usual (or external) percolation problem (EP) when the percolation current flows from the top to the bottom of the system, in IP case the voltage is applied through bars which are present in the hole located within the system. The EP problem has two major parameters: M-size of the system and a 0 -size of inclusions, bond size, etc. The IP problem holds one parameter more: size of the hole L. Numerical simulation shows that the critical indexes of conductance for the IP problem are very close to those in the EP problem. On the contrary, the indexes of the relative spectral noise density of 1/f noise and higher moments differ from those in the EP problem. The basics of these facts is discussed.

Fostering information problem solving skills through completion problems and prompts

NARCIS (Netherlands)

Frerejean, Jimmy; Brand-Gruwel, Saskia; Kirschner, Paul A.

2012-01-01

Frerejean, J., Brand-Gruwel, S., & Kirschner, P. A. (2012, November). Fostering information problem solving skills through completion problems and prompts. Poster presented at the ICO Fall School 2012, Girona, Spain.

The moment problem

CERN Document Server

Schmüdgen, Konrad

2017-01-01

This advanced textbook provides a comprehensive and unified account of the moment problem. It covers the classical one-dimensional theory and its multidimensional generalization, including modern methods and recent developments. In both the one-dimensional and multidimensional cases, the full and truncated moment problems are carefully treated separately. Fundamental concepts, results and methods are developed in detail and accompanied by numerous examples and exercises. Particular attention is given to powerful modern techniques such as real algebraic geometry and Hilbert space operators. A wide range of important aspects are covered, including the Nevanlinna parametrization for indeterminate moment problems, canonical and principal measures for truncated moment problems, the interplay between Positivstellensätze and moment problems on semi-algebraic sets, the fibre theorem, multidimensional determinacy theory, operator-theoretic approaches, and the existence theory and important special topics of multidime...

Structural Identification Problem

Directory of Open Access Journals (Sweden)

Suvorov Aleksei

2016-01-01

Full Text Available The identification problem of the existing structures though the Quasi-Newton and its modification, Trust region algorithms is discussed. For the structural problems, which could be represented by means of the mathematical modelling of the finite element code discussed method is extremely useful. The nonlinear minimization problem of the L2 norm for the structures with linear elastic behaviour is solved by using of the Optimization Toolbox of Matlab. The direct and inverse procedures for the composition of the desired function to minimize are illustrated for the spatial 3D truss structure as well as for the problem of plane finite elements. The truss identification problem is solved with 2 and 3 unknown parameters in order to compare the computational efforts and for the graphical purposes. The particular commands of the Matlab codes are present in this paper.

Integrating Multimedia and Physics Problems

Science.gov (United States)

Titus, Aaron P.

1997-11-01

Although expert problem solvers typically use pictorial representations when solving problems, novices tend to proceed from the given problem statement to a mathematical solution without first developing a visual representation of the problem. For this reason, multimedia may be an effective tool to enhance students' success at solving problems. However, merely presenting a video of motion described in a problem is not necessarily the most effective method as was found in a recent study of students' responses on Web-based homework questions. Rather, multimedia-focused problems, where data relevant to solving the problem is embedded in a video or animation, may be the best use of multimedia in problem solving. Examples of multimedia-enhanced problems and multimedia-focused problems will be demonstrated, and their differences from "traditional" problems will be highlighted. Recommendations on the use of multimedia with problem solving and preliminary data on students' success at solving these problems will be discussed.

The Solving of Problems in Chemistry: the more open-ended problems

Science.gov (United States)

Reid, Norman; Yang, Mei-Jung

2002-01-01

Most problem solving in chemistry tends to be algorithmic in nature, while problems in life tend to be very open ended. This paper offers a simple classification of problems and seeks to explore the many factors which may be important in the successful solving of problems. It considers the place of procedures and algorithms. It analyses the role of long-term memory, not only in terms of what is known, but how that knowledge was acquired. It notes the great importance of the limitations of working memory space and the importance of confidence which comes from experience. Finally, various psychological factors are discussed. This paper argues that solving open-ended problems is extremely important in education and that offering learners experience of this in a group work context is a helpful way forward.

Development of a problem solving evaluation instrument; untangling of specific problem solving assets

Science.gov (United States)

Adams, Wendy Kristine

The purpose of my research was to produce a problem solving evaluation tool for physics. To do this it was necessary to gain a thorough understanding of how students solve problems. Although physics educators highly value problem solving and have put extensive effort into understanding successful problem solving, there is currently no efficient way to evaluate problem solving skill. Attempts have been made in the past; however, knowledge of the principles required to solve the subject problem are so absolutely critical that they completely overshadow any other skills students may use when solving a problem. The work presented here is unique because the evaluation tool removes the requirement that the student already have a grasp of physics concepts. It is also unique because I picked a wide range of people and picked a wide range of tasks for evaluation. This is an important design feature that helps make things emerge more clearly. This dissertation includes an extensive literature review of problem solving in physics, math, education and cognitive science as well as descriptions of studies involving student use of interactive computer simulations, the design and validation of a beliefs about physics survey and finally the design of the problem solving evaluation tool. I have successfully developed and validated a problem solving evaluation tool that identifies 44 separate assets (skills) necessary for solving problems. Rigorous validation studies, including work with an independent interviewer, show these assets identified by this content-free evaluation tool are the same assets that students use to solve problems in mechanics and quantum mechanics. Understanding this set of component assets will help teachers and researchers address problem solving within the classroom.

Augmented neural networks and problem structure-based heuristics for the bin-packing problem

Science.gov (United States)

Kasap, Nihat; Agarwal, Anurag

2012-08-01

In this article, we report on a research project where we applied augmented-neural-networks (AugNNs) approach for solving the classical bin-packing problem (BPP). AugNN is a metaheuristic that combines a priority rule heuristic with the iterative search approach of neural networks to generate good solutions fast. This is the first time this approach has been applied to the BPP. We also propose a decomposition approach for solving harder BPP, in which subproblems are solved using a combination of AugNN approach and heuristics that exploit the problem structure. We discuss the characteristics of problems on which such problem structure-based heuristics could be applied. We empirically show the effectiveness of the AugNN and the decomposition approach on many benchmark problems in the literature. For the 1210 benchmark problems tested, 917 problems were solved to optimality and the average gap between the obtained solution and the upper bound for all the problems was reduced to under 0.66% and computation time averaged below 33 s per problem. We also discuss the computational complexity of our approach.

Pet Problems at Home: Pet Problems in the Community.

Science.gov (United States)

Soltow, Willow

1984-01-01

Discusses problems of pets in the community, examining the community's role related to disruptive pets and pet overpopulation. Also discusses pet problems at home, offering advice on selecting a pet, meeting a pet's needs, and disciplining pets. Includes a list of books, films/filmstrips, teaching materials, and various instructional strategies.…

Problem specific heuristics for group scheduling problems in cellular manufacturing

OpenAIRE

Neufeld, Janis Sebastian

2016-01-01

The group scheduling problem commonly arises in cellular manufacturing systems, where parts are grouped into part families. It is characterized by a sequencing task on two levels: on the one hand, a sequence of jobs within each part family has to be identified while, on the other hand, a family sequence has to be determined. In order to solve this NP-hard problem usually heuristic solution approaches are used. In this thesis different aspects of group scheduling are discussed and problem spec...

MUSCLE-BONE INTERACTIONS ACROSS AGE IN MEN

Directory of Open Access Journals (Sweden)

Ian J. Palmer

2006-03-01

Full Text Available This study examined the relationship of muscular strength and lean tissue with age-related patterns in bone mineral density (BMD in men 20-81 years of age. Subjects were assigned to one of three age groups, Young Men (YM, (n = 25, 20-39 yrs, Middle-aged Men (MM (n = 24, 40-59 yrs, and Older Men (OM (n = 23, 60-81 yrs. Isotonic and isokinetic strength was assessed for the quadriceps and hamstrings muscle groups. DXA (Lunar DPX-IQ was used to measure spine, hip, and total body BMD and body composition. OM had significantly lower (p < 0.05 total lean body mass (LBM than MM and lower leg lean mass (LM than YM and MM. OM had significantly lower (p < 0.01 BMD than YM and MM at the femoral neck and total hip sites and a higher proportion of OM were osteopenic and osteoporotic at the total hip site. Isotonic and isokinetic strength for both muscle groups was positively related (p < 0.05 with the hip BMD sites (r = 0.38-.67. Leg LM also was positively related to hip BMD (r = 0.37-.58. Multiple Regression analyses determined that age and lean mass (LBM or leg LM were significant predictors (p < 0.05 of femoral neck, and total hip BMD, while lean mass (LBM or leg LM was a significant predictor (p < 0.05 of BMD at the spine and trochanter sites. Isotonic and isokinetic leg strength variables were significant predictors (p < 0.05 of the total body, total hip and trochanter BMD. In conclusion, leg strength, leg LM, and total LBM were significant predictors of BMD in men, independent of age. These findings emphasize the importance of maintaining lean body mass for the bone health of aging men

Absence of the common gamma chain (γ(c)), a critical component of the Type I IL-4 receptor, increases the severity of allergic lung inflammation.

Science.gov (United States)

Dasgupta, Preeta; Qi, Xiulan; Smith, Elizabeth P; Keegan, Achsah D

2013-01-01

The T(H)2 cytokines, IL-4 and IL-13, play critical roles in inducing allergic lung inflammation and drive the alternative activation of macrophages (AAM). Although both cytokines share receptor subunits, IL-4 and IL-13 have differential roles in asthma pathogenesis: IL-4 regulates T(H)2 cell differentiation, while IL-13 regulates airway hyperreactivity and mucus production. Aside from controlling T(H)2 differentiation, the unique contribution of IL-4 signaling via the Type I receptor in airway inflammation remains unclear. Therefore, we analyzed responses in mice deficient in gamma c (γ(c)) to elucidate the role of the Type I IL-4 receptor. OVA primed CD4⁺ OT-II T cells were adoptively transferred into RAG2⁻/⁻ and γ(c)⁻/⁻ mice and allergic lung disease was induced. Both γ(c)⁻/⁻ and γcxRAG2⁻/⁻ mice developed increased pulmonary inflammation and eosinophilia upon OVA challenge, compared to RAG2⁻/⁻ mice. Characteristic AAM proteins FIZZ1 and YM1 were expressed in lung epithelial cells in both mouse strains, but greater numbers of FIZZ1+ or YM1+ airways were present in γ(c)⁻/⁻ mice. Absence of γc in macrophages, however, resulted in reduced YM1 expression. We observed higher T(H)2 cytokine levels in the BAL and an altered DC phenotype in the γ(c)⁻/⁻ recipient mice suggesting the potential for dysregulated T cell and dendritic cell (DC) activation in the γ(c)-deficient environment. These results demonstrate that in absence of the Type I IL-4R, the Type II R can mediate allergic responses in the presence of T(H)2 effectors. However, the Type I R regulates AAM protein expression in macrophages.

On Euler's problem

International Nuclear Information System (INIS)

Egorov, Yurii V

2013-01-01

We consider the classical problem on the tallest column which was posed by Euler in 1757. Bernoulli-Euler theory serves today as the basis for the design of high buildings. This problem is reduced to the problem of finding the potential for the Sturm-Liouville equation corresponding to the maximum of the first eigenvalue. The problem has been studied by many mathematicians but we give the first rigorous proof of the existence and uniqueness of the optimal column and we give new formulae which let us find it. Our method is based on a new approach consisting in the study of critical points of a related nonlinear functional. Bibliography: 6 titles.

Biodegradation of phenanthrene in artificial seawater by using free ...

African Journals Online (AJOL)

STORAGESEVER

2010-05-03

May 3, 2010 ... Abdel-Mohdy FA, Abdel-Halim ES, Abu-Ayana YM, El-Sawy SM (2009). Rice straw as a new resource for some beneficial uses. Carbohyd. Polym. 75: 44-51. Bjorlykke K, Gran K (1994). Salinity variations in North Sea formation waters: implications for large-scale fluid movements. Mar. Petrol. Geol. 11: 5-9.

Egyptian Journal of Pediatric Allergy and Immunology (The) - Vol 1 ...

African Journals Online (AJOL)

YM El-Gamal, HY Tomoum, NE Nagy, TB Kamel, 14-21. Prevalence and clinical value of IgA and hidden rheumatoid factors in juvenile rheumatoid arthritis · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. ZA El-Sayed, GA Mostafa, NT Ali, AI Hawal, 22-29 ...

Radionuclide Transport Models Under Ambient Conditions

International Nuclear Information System (INIS)

Moridis, G.; Hu, Q.

2001-01-01

The purpose of Revision 00 of this Analysis/Model Report (AMR) is to evaluate (by means of 2-D semianalytical and 3-D numerical models) the transport of radioactive solutes and colloids in the unsaturated zone (UZ) under ambient conditions from the potential repository horizon to the water table at Yucca Mountain (YM), Nevada

Noticing relevant problem features: activating prior knowledge affects problem solving by guiding encoding

Science.gov (United States)

Crooks, Noelle M.; Alibali, Martha W.

2013-01-01

This study investigated whether activating elements of prior knowledge can influence how problem solvers encode and solve simple mathematical equivalence problems (e.g., 3 + 4 + 5 = 3 + __). Past work has shown that such problems are difficult for elementary school students (McNeil and Alibali, 2000). One possible reason is that children's experiences in math classes may encourage them to think about equations in ways that are ultimately detrimental. Specifically, children learn a set of patterns that are potentially problematic (McNeil and Alibali, 2005a): the perceptual pattern that all equations follow an “operations = answer” format, the conceptual pattern that the equal sign means “calculate the total”, and the procedural pattern that the correct way to solve an equation is to perform all of the given operations on all of the given numbers. Upon viewing an equivalence problem, knowledge of these patterns may be reactivated, leading to incorrect problem solving. We hypothesized that these patterns may negatively affect problem solving by influencing what people encode about a problem. To test this hypothesis in children would require strengthening their misconceptions, and this could be detrimental to their mathematical development. Therefore, we tested this hypothesis in undergraduate participants. Participants completed either control tasks or tasks that activated their knowledge of the three patterns, and were then asked to reconstruct and solve a set of equivalence problems. Participants in the knowledge activation condition encoded the problems less well than control participants. They also made more errors in solving the problems, and their errors resembled the errors children make when solving equivalence problems. Moreover, encoding performance mediated the effect of knowledge activation on equivalence problem solving. Thus, one way in which experience may affect equivalence problem solving is by influencing what students encode about the

Problem representation and mathematical problem solving of students of varying math ability.

Science.gov (United States)

Krawec, Jennifer L

2014-01-01

The purpose of this study was to examine differences in math problem solving among students with learning disabilities (LD, n = 25), low-achieving students (LA, n = 30), and average-achieving students (AA, n = 29). The primary interest was to analyze the processes students use to translate and integrate problem information while solving problems. Paraphrasing, visual representation, and problem-solving accuracy were measured in eighth grade students using a researcher-modified version of the Mathematical Processing Instrument. Results indicated that both students with LD and LA students struggled with processing but that students with LD were significantly weaker than their LA peers in paraphrasing relevant information. Paraphrasing and visual representation accuracy each accounted for a statistically significant amount of variance in problem-solving accuracy. Finally, the effect of visual representation of relevant information on problem-solving accuracy was dependent on ability; specifically, for students with LD, generating accurate visual representations was more strongly related to problem-solving accuracy than for AA students. Implications for instruction for students with and without LD are discussed.

EFFECT OF PROBLEM BASED LEARNING AND MODEL CRITICAL THINKING ABILITY TO PROBLEM SOLVING SKILLS

Directory of Open Access Journals (Sweden)

Unita S. Zuliani Nasution

2016-12-01

Full Text Available The purposes of this research were to analyze the different between physic resolving problem ability by using problem based learning model and direct instruction model, the different of physic resolving problem ability between the students that have critical thinking ability upper the average and the students that have critical thinking ability under the average, and the interaction of problem based learning model toward critical thinking ability and students’ physic resolving problem ability. This research was quasy experimental research that use critical thinking ability tests and physic resolving problem ability tests as the instruments. Result of the research showed that the students’ physic resolving problem ability by using problem based learning model was better than by using direct instruction model, students’ physic resolving problem ability and critical thinking ability upper the average showed better different and result than students’ critical thinking ability under the average, besides there was an interaction between problem based learning model and critical thinking ability in improving students’ physic resolving problem ability.

The problem of criticality and initial-value problem in neutron transport theory

International Nuclear Information System (INIS)

Kyncl, J.

1984-10-01

The problem of criticality and the initial value problem are studied in the case of a linear Boltzmann equation and of both finite and infinite media. The space of functions where the problems are solved is chosen in such a way as to cover a wide range of physical situations. The asymptotic time behavior of the solution to the initial-value problem is also discussed, and main results are summarized in three basic theorems. (author)

A METHOD FOR THE SIMULTANEOUS ESTIMATION OF ATMOSPHERIC PARAMETERS USING THE PHOTOMETRIC INDICES IN THE uvby COLOR SYSTEM

International Nuclear Information System (INIS)

Kim, Chulhee; Moon, B.-K.

2011-01-01

A new method was developed to estimate the effective temperature, surface gravity, and metallicity of cool stars using only photometric indices in the uvby color system. In a graphical method, T eff and log g were determined for all of the different values of [Fe/H] using model atmosphere grids with respect to (b - y):c 1 and (b - y):m 1 pair indices. Then, a three-dimensional figure where X-, Y-, and Z-axes correspond to T eff , log g, and [Fe/H] was produced. By reading an intersection of two curves formed by a connection of three parameters obtained from the (b - y):c 1 and (b - y):m 1 pair indices on each of the three projected planes, T eff , log g, and [Fe/H] were determined simultaneously. In addition, an analytical method was devised based on the same algorithm developed for the graphical method. The new method was applied to a number of field dwarfs and giants, and the results were compared with those from a spectroscopic method and other photometric calibrations.

Meson widths from string worldsheet instantons

International Nuclear Information System (INIS)

Faulkner, Thomas; Liu, Hong

2009-01-01

We show that open strings living on a D-brane which lies outside an AdS black hole can tunnel into the black hole through worldsheet instantons. These instantons have a simple interpretation in terms of thermal quarks in the dual Yang-Mills (YM) theory. As an application we calculate the width of a meson in a strongly coupled quark-gluon plasma which is described holographically as a massless mode on a D7 brane in AdS 5 xS 5 . While the width of the meson is zero to all orders in the 1/√(λ) expansion with λ the 't Hooft coupling, it receives non-perturbative contributions in 1/√(λ) from worldsheet instantons. We find that the width increases quadratically with momentum at large momentum and comment on potential phenomenological implications of this enhancement for heavy ion collisions. We also comment on how this non-perturbative effect has important consequences for the phase structure of the YM theory obtained in the classical gravity limit

Hsp70-Bag3 interactions regulate cancer-related signaling networks.

Science.gov (United States)

Colvin, Teresa A; Gabai, Vladimir L; Gong, Jianlin; Calderwood, Stuart K; Li, Hu; Gummuluru, Suryaram; Matchuk, Olga N; Smirnova, Svetlana G; Orlova, Nina V; Zamulaeva, Irina A; Garcia-Marcos, Mikel; Li, Xiaokai; Young, Z T; Rauch, Jennifer N; Gestwicki, Jason E; Takayama, Shinichi; Sherman, Michael Y

2014-09-01

Bag3, a nucleotide exchange factor of the heat shock protein Hsp70, has been implicated in cell signaling. Here, we report that Bag3 interacts with the SH3 domain of Src, thereby mediating the effects of Hsp70 on Src signaling. Using several complementary approaches, we established that the Hsp70-Bag3 module is a broad-acting regulator of cancer cell signaling by modulating the activity of the transcription factors NF-κB, FoxM1, Hif1α, the translation regulator HuR, and the cell-cycle regulators p21 and survivin. We also identified a small-molecule inhibitor, YM-1, that disrupts the Hsp70-Bag3 interaction. YM-1 mirrored the effects of Hsp70 depletion on these signaling pathways, and in vivo administration of this drug was sufficient to suppress tumor growth in mice. Overall, our results defined Bag3 as a critical factor in Hsp70-modulated signaling and offered a preclinical proof-of-concept that the Hsp70-Bag3 complex may offer an appealing anticancer target. ©2014 American Association for Cancer Research.

Pre-Service Mathematics Teachers’ Problem Solving Processes with Geometer’s Sketchpad: Mirror Problem

OpenAIRE

ÖÇAL, Mehmet Fatih; ŞİMŞEK, Mertkan

2016-01-01

Problem solving skill is the core of mathematics education and its importance cannot be denied. This study specifically examined 56 freshmen pre-service mathematics teachers’ problem solving processes on a specific problem with the help of Geometer’s Sketchpad (GSP). They were grouped into two-person teams to solve a problem called "the mirror problem". They were expected to solve it by means of GSP. According to their works on GSP and related reflections, there appeared two differe...

Fostering Information Problem Solving Skills Through Completion Problems and Prompts

NARCIS (Netherlands)

Frerejean, Jimmy; Brand-Gruwel, Saskia; Kirschner, Paul A.

2012-01-01

Frerejean, J., Brand-Gruwel, S., & Kirschner, P. A. (2012, September). Fostering Information Problem Solving Skills Through Completion Problems and Prompts. Poster presented at the EARLI SIG 6 & 7 "Instructional Design" and "Learning and Instruction with Computers", Bari, Italy.

Semidefinite linear complementarity problems

International Nuclear Information System (INIS)

Eckhardt, U.

1978-04-01

Semidefinite linear complementarity problems arise by discretization of variational inequalities describing e.g. elastic contact problems, free boundary value problems etc. In the present paper linear complementarity problems are introduced and the theory as well as the numerical treatment of them are described. In the special case of semidefinite linear complementarity problems a numerical method is presented which combines the advantages of elimination and iteration methods without suffering from their drawbacks. This new method has very attractive properties since it has a high degree of invariance with respect to the representation of the set of all feasible solutions of a linear complementarity problem by linear inequalities. By means of some practical applications the properties of the new method are demonstrated. (orig.) [de

The Swedish drug problem: Conceptual understanding and problem handling, 1839–2011

Directory of Open Access Journals (Sweden)

Edman Johan

2014-12-01

Full Text Available AIM - To analyse the Swedish drug question by examining dominant concepts used to portray the problem in the years 1839-2011. Theoretically, we understand these concepts as ideological tools that shape the political initiatives and administrative efforts to deal with the problem. The study is based on two kinds of source material: articles in medical journals from the years 1839-1964 and public reports on vagrancy, the alcohol problem, mental health and the drug problem from the years 1882-2011.

The Elder Problem

Directory of Open Access Journals (Sweden)

John W. Elder

2017-03-01

Full Text Available This paper presents an autobiographical and biographical historical account of the genesis, evolution and resolution of the Elder Problem. It begins with John W. Elder and his autobiographical story leading to his groundbreaking work on natural convection at Cambridge in the 1960’s. His seminal work published in the Journal of Fluid Mechanics in 1967 became the basis for the modern benchmark of variable density flow simulators that we know today as “The Elder Problem”. There have been well known and major challenges with the Elder Problem model benchmark—notably the multiple solutions that were ultimately uncovered using different numerical models. Most recently, it has been shown that the multiple solutions are indeed physically realistic bifurcation solutions to the Elder Problem and not numerically spurious artefacts. The quandary of the Elder Problem has now been solved—a major scientific breakthrough for fluid mechanics and for numerical modelling. This paper—records, reflections, reminiscences, stories and anecdotes—is an historical autobiographical and biographical memoir. It is the personal story of the Elder Problem told by some of the key scientists who established and solved the Elder Problem. 2017 marks the 50 year anniversary of the classical work by John W. Elder published in Journal of Fluid Mechanics in 1967. This set the stage for this scientific story over some five decades. This paper is a celebration and commemoration of the life and times of John W. Elder, the problem named in his honour, and some of the key scientists who worked on, and ultimately solved, it.

Phase Transitions in Planning Problems: Design and Analysis of Parameterized Families of Hard Planning Problems

Science.gov (United States)

Hen, Itay; Rieffel, Eleanor G.; Do, Minh; Venturelli, Davide

2014-01-01

There are two common ways to evaluate algorithms: performance on benchmark problems derived from real applications and analysis of performance on parametrized families of problems. The two approaches complement each other, each having its advantages and disadvantages. The planning community has concentrated on the first approach, with few ways of generating parametrized families of hard problems known prior to this work. Our group's main interest is in comparing approaches to solving planning problems using a novel type of computational device - a quantum annealer - to existing state-of-the-art planning algorithms. Because only small-scale quantum annealers are available, we must compare on small problem sizes. Small problems are primarily useful for comparison only if they are instances of parametrized families of problems for which scaling analysis can be done. In this technical report, we discuss our approach to the generation of hard planning problems from classes of well-studied NP-complete problems that map naturally to planning problems or to aspects of planning problems that many practical planning problems share. These problem classes exhibit a phase transition between easy-to-solve and easy-to-show-unsolvable planning problems. The parametrized families of hard planning problems lie at the phase transition. The exponential scaling of hardness with problem size is apparent in these families even at very small problem sizes, thus enabling us to characterize even very small problems as hard. The families we developed will prove generally useful to the planning community in analyzing the performance of planning algorithms, providing a complementary approach to existing evaluation methods. We illustrate the hardness of these problems and their scaling with results on four state-of-the-art planners, observing significant differences between these planners on these problem families. Finally, we describe two general, and quite different, mappings of planning

Problems in differential equations

CERN Document Server

Brenner, J L

2013-01-01

More than 900 problems and answers explore applications of differential equations to vibrations, electrical engineering, mechanics, and physics. Problem types include both routine and nonroutine, and stars indicate advanced problems. 1963 edition.

Obstacle problems in mathematical physics

CERN Document Server

Rodrigues, J-F

1987-01-01

The aim of this research monograph is to present a general account of the applicability of elliptic variational inequalities to the important class of free boundary problems of obstacle type from a unifying point of view of classical Mathematical Physics.The first part of the volume introduces some obstacle type problems which can be reduced to variational inequalities. Part II presents some of the main aspects of the theory of elliptic variational inequalities, from the abstract hilbertian framework to the smoothness of the variational solution, discussing in general the properties of the free boundary and including some results on the obstacle Plateau problem. The last part examines the application to free boundary problems, namely the lubrication-cavitation problem, the elastoplastic problem, the Signorini (or the boundary obstacle) problem, the dam problem, the continuous casting problem, the electrochemical machining problem and the problem of the flow with wake in a channel past a profile.

Perbedaan Keterampilan Pemecahan Masalah pada Pembelajaran Fisika Menggunakan Metode Problem Posing dan Problem Solving

OpenAIRE

Rahman, Adetya; Hartini, Sri; An'nur, Syubhan

2015-01-01

Teachers should be able to choose the method of learning that can help students in learning physics, namely the method of problem posing and problem solving method. The purposes of this study are : (1) describe the learning physics skills by using problem posing method, (2) describe the learning physics skills by using problem solving method, and (3) know difference between learning physics skills by using problem posing method and problem solving method in class XI of Science SMAN 6 Banjarma...

ITOUGH2 sample problems

International Nuclear Information System (INIS)

Finsterle, S.

1997-11-01

This report contains a collection of ITOUGH2 sample problems. It complements the ITOUGH2 User's Guide [Finsterle, 1997a], and the ITOUGH2 Command Reference [Finsterle, 1997b]. ITOUGH2 is a program for parameter estimation, sensitivity analysis, and uncertainty propagation analysis. It is based on the TOUGH2 simulator for non-isothermal multiphase flow in fractured and porous media [Preuss, 1987, 1991a]. The report ITOUGH2 User's Guide [Finsterle, 1997a] describes the inverse modeling framework and provides the theoretical background. The report ITOUGH2 Command Reference [Finsterle, 1997b] contains the syntax of all ITOUGH2 commands. This report describes a variety of sample problems solved by ITOUGH2. Table 1.1 contains a short description of the seven sample problems discussed in this report. The TOUGH2 equation-of-state (EOS) module that needs to be linked to ITOUGH2 is also indicated. Each sample problem focuses on a few selected issues shown in Table 1.2. ITOUGH2 input features and the usage of program options are described. Furthermore, interpretations of selected inverse modeling results are given. Problem 1 is a multipart tutorial, describing basic ITOUGH2 input files for the main ITOUGH2 application modes; no interpretation of results is given. Problem 2 focuses on non-uniqueness, residual analysis, and correlation structure. Problem 3 illustrates a variety of parameter and observation types, and describes parameter selection strategies. Problem 4 compares the performance of minimization algorithms and discusses model identification. Problem 5 explains how to set up a combined inversion of steady-state and transient data. Problem 6 provides a detailed residual and error analysis. Finally, Problem 7 illustrates how the estimation of model-related parameters may help compensate for errors in that model

New Approach to Analyzing Physics Problems: A Taxonomy of Introductory Physics Problems

Science.gov (United States)

Teodorescu, Raluca E.; Bennhold, Cornelius; Feldman, Gerald; Medsker, Larry

2013-01-01

This paper describes research on a classification of physics problems in the context of introductory physics courses. This classification, called the Taxonomy of Introductory Physics Problems (TIPP), relates physics problems to the cognitive processes required to solve them. TIPP was created in order to design educational objectives, to develop…

Lin-Na and Yong-Xiu Afr J Tradit Complement Altern Med. (2014) 11 ...

African Journals Online (AJOL)

cadewumi

Evaluation of anti-athletic fatigue activity of Schizandra chinensis aqueous extracts in mice. Afr J Pharm Pharmacol 3: 593-597. 4. Cao, Y., Hu, Y., Liu, P., Zhao, H.X., Zhou, X.J., and Wei, Y.M. (2012). Effects of a Chinese traditional formula Kai Xin San (KXS) on chronic fatigue syndrome mice induced by forced wheel running ...

Egyptian Journal of Pediatric Allergy and Immunology (The) - Vol 15 ...

African Journals Online (AJOL)

ARIA 2016 Executive Summary Integrated care pathways for predictive medicine across the life cycle · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Y.M. El-Gamal, E.M. Hossny, Z.A. El-Sayed, M El-Seify, S.M. Reda, S.S. El-Sayed, I Agache, C Bachert, A Bedbrook, ...

phytochemical and antimicrobial properties of commiphora

African Journals Online (AJOL)

DR. AMINU

2014-06-01

Jun 1, 2014 ... CIPIH Study Nine on TM, Draft Report. 1-172. Sani, Y.M., Musa, A.M., Yaro, A.H., Sani, M.B.,. Amoley, A. and Magaji, M.G. (2013). Phytochemical screening and evaluation of analgesic and anti inflammatory activities of the Methanol Leaf Extract of Cissus polyantha. J. Med. Sci., 1682-4474. Sibanda T. and ...

Analysis of mathematical problem-solving ability based on metacognition on problem-based learning

Science.gov (United States)

Mulyono; Hadiyanti, R.

2018-03-01

Problem-solving is the primary purpose of the mathematics curriculum. Problem-solving abilities influenced beliefs and metacognition. Metacognition as superordinate capabilities can direct, regulate cognition and motivation and then problem-solving processes. This study aims to (1) test and analyzes the quality of problem-based learning and (2) investigate the problem-solving capabilities based on metacognition. This research uses mixed method study with The subject research are class XI students of Mathematics and Science at High School Kesatrian 2 Semarang which divided into tacit use, aware use, strategic use and reflective use level. The collecting data using scale, interviews, and tests. The data processed with the proportion of test, t-test, and paired samples t-test. The result shows that the students with levels tacit use were able to complete the whole matter given, but do not understand what and why a strategy is used. Students with aware use level were able to solve the problem, be able to build new knowledge through problem-solving to the indicators, understand the problem, determine the strategies used, although not right. Students on the Strategic ladder Use can be applied and adopt a wide variety of appropriate strategies to solve the issues and achieved re-examine indicators of process and outcome. The student with reflective use level is not found in this study. Based on the results suggested that study about the identification of metacognition in problem-solving so that the characteristics of each level of metacognition more clearly in a more significant sampling. Teachers need to know in depth about the student metacognitive activity and its relationship with mathematical problem solving and another problem resolution.

Simon on Problem-Solving

DEFF Research Database (Denmark)

Foss, Kirsten; Foss, Nicolai Juul

as a general approach to problem solving. We apply these Simonian ideas to organizational issues, specifically new organizational forms. Specifically, Simonian ideas allow us to develop a morphology of new organizational forms and to point to some design problems that characterize these forms.Keywords: Herbert...... Simon, problem-solving, new organizational forms. JEL Code: D23, D83......Two of Herbert Simon's best-known papers are "The Architecture of Complexity" and "The Structure of Ill-Structured Problems." We discuss the neglected links between these two papers, highlighting the role of decomposition in the context of problems on which constraints have been imposed...

Problem-Based Learning: Student Engagement, Learning and Contextualized Problem-Solving. Occasional Paper

Science.gov (United States)

Mossuto, Mark

2009-01-01

The adoption of problem-based learning as a teaching method in the advertising and public relations programs offered by the Business TAFE (Technical and Further Education) School at RMIT University is explored in this paper. The effect of problem-based learning on student engagement, student learning and contextualised problem-solving was…

Investigating Mathematics Teachers Candidates' Knowledge about Problem Solving Strategies through Problem Posing

Science.gov (United States)

Ünlü, Melihan

2017-01-01

The aim of the study was to determine mathematics teacher candidates' knowledge about problem solving strategies through problem posing. This qualitative research was conducted with 95 mathematics teacher candidates studying at education faculty of a public university during the first term of the 2015-2016 academic year in Turkey. Problem Posing…

Pelvic floor muscle problems mediate sexual problems in young adult rape victims

NARCIS (Netherlands)

Postma, Riemke; Bicanic, Iva; van der Vaart, Huub; Laan, Ellen

2013-01-01

Prior studies have addressed sexual abuse and sexual function in adult women. No studies have focused on the effect of adolescence rape on sexual functioning. To investigate the effect of rape on sexual problems and on pelvic floor problems, as well as the mediating role of pelvic floor problems on

Parent-Reported Psychological and Sleep Problems in a Preschool-Aged Community Sample: Prevalence of Sleep Problems in Children with and without Emotional/Behavioural Problems

OpenAIRE

Salater, Julie; Røhr, Marthe

2010-01-01

Objective : To examine (a) the prevalence of sleep problems among 4-year-olds in the general population, (b) the prevalence of sleep problems among children with emotional and/or behavioural problems, and (c) whether specific sleep problems are associated with particular emotional/behavioural problems. Method: Using The Preschool Age Psychiatric Assessment (PAPA) , data about sleep and emotional/behavioural problems was obtained from 727 parents of 4-year-olds, recruited for a large...

Problem solving and problem strategies in the teaching and learning ...

African Journals Online (AJOL)

Perennial poor performance recorded annually in both internal and external examinations in Mathematics has been a great concern for the Mathematics Educators in Nigeria. This paper discusses problem-solving and influence of problem-solving strategies on students' performance in mathematics. The concept of ...

Students’ Mathematical Problem-Solving Abilities Through The Application of Learning Models Problem Based Learning

Science.gov (United States)

Nasution, M. L.; Yerizon, Y.; Gusmiyanti, R.

2018-04-01

One of the purpose mathematic learning is to develop problem solving abilities. Problem solving is obtained through experience in questioning non-routine. Improving students’ mathematical problem-solving abilities required an appropriate strategy in learning activities one of them is models problem based learning (PBL). Thus, the purpose of this research is to determine whether the problem solving abilities of mathematical students’ who learn to use PBL better than on the ability of students’ mathematical problem solving by applying conventional learning. This research included quasi experiment with static group design and population is students class XI MIA SMAN 1 Lubuk Alung. Class experiment in the class XI MIA 5 and class control in the class XI MIA 6. The instrument of final test students’ mathematical problem solving used essay form. The result of data final test in analyzed with t-test. The result is students’ mathematical problem solving abilities with PBL better then on the ability of students’ mathematical problem solving by applying conventional learning. It’s seen from the high percentage achieved by the group of students who learn to use PBL for each indicator of students’ mathematical problem solving.

Problem-solving with multiple interdependent criteria: better solution to complex problems

International Nuclear Information System (INIS)

Carlsson, C.; Fuller, R.

1996-01-01

We consider multiple objective programming (MOP) problems with additive interdependencies, this is when the states of some chosen objective are attained through supportive or inhibitory feed-backs from several other objectives. MOP problems with independent objectives (when the cause-effect relations between the decision variables and the objectives are completely known) will be treated as special cases of the MOP in which we have interdependent objectives. We illustrate our ideas by a simple three-objective real-life problem

The rational complementarity problem

NARCIS (Netherlands)

Heemels, W.P.M.H.; Schumacher, J.M.; Weiland, S.

1999-01-01

An extension of the linear complementarity problem (LCP) of mathematical programming is the so-called rational complementarity problem (RCP). This problem occurs if complementarity conditions are imposed on input and output variables of linear dynamical input/state/output systems. The resulting

The Effect of Problem Solving and Problem Posing Models and Innate Ability to Students Achievement

Directory of Open Access Journals (Sweden)

Ratna Kartika Irawati

2015-04-01

Full Text Available Pengaruh Model Problem Solving dan Problem Posing serta Kemampuan Awal terhadap Hasil Belajar Siswa   Abstract: Chemistry concepts understanding features abstract quality and requires higher order thinking skills. Yet, the learning on chemistry has not boost the higher order thinking skills of the students. The use of the learning model of Problem Solving and Problem Posing in observing the innate ability of the student is expected to resolve the issue. This study aims to determine the learning model which is effective to improve the study of the student with different level of innate ability. This study used the quasi-experimental design. The research data used in this research is the quiz/test of the class which consist of 14 multiple choice questions and 5 essay questions. The data analysis used is ANOVA Two Ways. The results showed that Problem Posing is more effective to improve the student compared to Problem Solving, students with high level of innate ability have better outcomes in learning rather than the students with low level of innate ability after being applied with the Problem solving and Problem posing model, further, Problem Solving and Problem Posing is more suitable to be applied to the students with high level of innate ability. Key Words: problem solving, problem posing, higher order thinking skills, innate ability, learning outcomes   Abstrak: Pemahaman konsep-konsep kimia yang bersifat abstrak membutuhkan keterampilan berpikir tingkat tinggi. Pembelajaran kimia belum mendorong siswa melakukan keterampilan berpikir tingkat tinggi. Penggunaan model pembelajaran Problem Solving dan Problem Posing dengan memperhatikan kemampuan awal siswa diduga dapat mengatasi masalah tersebut. Penelitian ini bertujuan untuk mengetahui model pembelajaran yang efektif dalam meningkatkan hasil belajar dengan kemampuan awal siswa yang berbeda. Penelitian ini menggunakan rancangan eksperimen semu. Data penelitian menggunakan tes hasil belajar

Diagrams benefit symbolic problem-solving.

Science.gov (United States)

Chu, Junyi; Rittle-Johnson, Bethany; Fyfe, Emily R

2017-06-01

The format of a mathematics problem often influences students' problem-solving performance. For example, providing diagrams in conjunction with story problems can benefit students' understanding, choice of strategy, and accuracy on story problems. However, it remains unclear whether providing diagrams in conjunction with symbolic equations can benefit problem-solving performance as well. We tested the impact of diagram presence on students' performance on algebra equation problems to determine whether diagrams increase problem-solving success. We also examined the influence of item- and student-level factors to test the robustness of the diagram effect. We worked with 61 seventh-grade students who had received 2 months of pre-algebra instruction. Students participated in an experimenter-led classroom session. Using a within-subjects design, students solved algebra problems in two matched formats (equation and equation-with-diagram). The presence of diagrams increased equation-solving accuracy and the use of informal strategies. This diagram benefit was independent of student ability and item complexity. The benefits of diagrams found previously for story problems generalized to symbolic problems. The findings are consistent with cognitive models of problem-solving and suggest that diagrams may be a useful additional representation of symbolic problems. © 2017 The British Psychological Society.

Modified and fuzzified general problem solver for 'monkey and banana' problem

International Nuclear Information System (INIS)

Sano, Norihide; Takahashi, Ryoichi.

1994-01-01

Automatic operation is important for the in-service inspection of nuclear power stations of the decommission of retired plants. Master and slave control will be introduced for work-robot control. It is desirable that the slave possess problem-solving capabilities. In this paper we assume that the slave incorporates the general problem solver (GPS) algorithm. In view of having solved the 'monkey and banana' problem, the slave system is regarded as reasonable alternative which incorporates the capability of problem-solving. Basically, the GPS solves a problem by reducing the difference between the initial state and goal state, and hence the performance of GPS depends on selection of the difference to be reduced. The conventional GPS is given the order of importance of the differences in advance. In this study, the GPS was improved by making use of the rules which determine the order. When several choices are available for the given difference, a fuzzified decision to determine the necessary action is made, as demonstrated in this paper. (author)

The vanishing discount problem and viscosity Mather measures. Part 2: boundary value problems

OpenAIRE

Ishii, Hitoshi; Mitake, Hiroyoshi; Tran, Hung V.

2016-01-01

In arXiv:1603.01051 (Part 1 of this series), we have introduced a variational approach to studying the vanishing discount problem for fully nonlinear, degenerate elliptic, partial differential equations in a torus. We develop this approach further here to handle boundary value problems. In particular, we establish new representation formulas for solutions of discount problems, critical values, and use them to prove convergence results for the vanishing discount problems.

How does maternal oxytocin influence children's mental health problem and maternal mental health problem?

Science.gov (United States)

Tse, Wai S; Siu, Angela F Y; Wong, Tracy K Y

2017-12-01

This study aims to explore the interrelationship among maternal oxytocin (OT) responsiveness, maternal mental health, maternal parenting behavior, and mental health of children under a free-play interaction. 61 mother-child dyads were recruited for the study. Maternal mental health problem and parenting self-efficacy were measured using self-reported questionnaires. The mental health problems of children were also evaluated using a mother-reported questionnaire. Furthermore, salivary OT was collected before and after a standardized 10min free-play interaction. Parenting behaviors, including eye gaze and touch, were measured during the free-play interaction. Maternal OT responsiveness was significantly associated with less maternal mental health problem, touch frequency, and mental health problem of children but not with parenting self-efficacy. In the multivariate linear regression analysis that considers maternal OT responsiveness and maternal and children's mental health problems, maternal OT responsiveness was not associated with the mental health problems of children. This result suggested that maternal mental health problem played a mediational role between maternal OT responsiveness and the mental health problem of children. Results supported the assertion that maternal OT responsiveness contributed to the increased risk of maternal mental health problems and, subsequently, the risk of mental health problems of their children. Copyright © 2017 Elsevier B.V. All rights reserved.

The ultimate safe (US) Reactor: A concept for the third millenium

International Nuclear Information System (INIS)

Gat, U.

1986-01-01

The Ultimate Safe (U.S.) Reactor is based on a novel safety concept. Fission products in the reactor are allowed to accumulate only to a level at which they would constitute a harmless source term. Removal of fission products also removes the decay heat - the driving force for the source term. The reactor has no excess criticality and is controlled by the reactivity temperature coefficient. Safety is inherent and passive. Waste is removed from the site promptly

Pollution problems plague Poland

International Nuclear Information System (INIS)

Bajsarowicz, J.F.

1989-01-01

Poland's environmental problems are said to stem from investments in heavy industries that require enormous quantities of power and from the exploitation of two key natural resources: coal and sulfur. Air and water pollution problems and related public health problems are discussed

Study the Problem.

Science.gov (United States)

Choate, Joyce S.

1990-01-01

The initial step of a strategic process for solving mathematical problems, "studying the question," is discussed. A lesson plan for teaching students to identify and revise arithmetic problems is presented, involving directed instruction and supervised practice. (JDD)

The art of problem posing

CERN Document Server

Brown, Stephen I

1990-01-01

Updated and expanded, this second edition satisfies the same philosophical objective as the first -- to show the importance of problem posing. Although interest in mathematical problem solving increased during the past decade, problem posing remained relatively ignored. The Art of Problem Posing draws attention to this equally important act and is the innovator in the field. Special features include: * an exploration ofthe logical relationship between problem posing and problem solving * a special chapter devoted to teaching problem posing as a separate course * sketches, drawings, diagrams, and cartoons that illustrate the schemes proposed * a special section on writing in mathematics.

Reproductive autonomy, the non-identity problem, and the non-person problem.

Science.gov (United States)

DiSilvestro, Russell

2009-01-01

The Non-Identity Problem is the problem of explaining the apparent wrongness of a decision that does not harm people, especially since some of the people affected by the decision would not exist at all were it not for the decision. One approach to this problem, in the context of reproductive decisions, is to focus on wronging, rather than harming, one's offspring. But a Non-Person Problem emerges for any view that claims (1) that only persons can be wronged and (2) that the person-making properties allow for there to be human non-persons. Consider an individual human organism that is prevented from ever possessing the person-making properties. On person-only accounts of the victims of wronging, this organism cannot be wronged by anyone. Hence even individuals whose decisions prevent it from ever possessing the person-making properties cannot wrong it. But this is counter-intuitive. We can think of examples where a human organism is wronged by precisely those decisions that prevent it from possessing the person-making properties. The best solution to this problem, in the case where the person-making property is rational self-governance in pursuit of a meaningful life, is to adjust the concept of a person so that it refers, not merely to those with the immediate capacity for rational self-governance in pursuit of a meaningful life, but also to those with a higher-order capacity for such self-governance. Any solution to the Non-Identity Problem that focuses on wronging rather than harming should incorporate this sort of solution to the Non-Person Problem.

Solved problems in electrochemistry

International Nuclear Information System (INIS)

Piron, D.L.

2004-01-01

This book presents calculated solutions to problems in fundamental and applied electrochemistry. It uses industrial data to illustrate scientific concepts and scientific knowledge to solve practical problems. It is subdivided into three parts. The first uses modern basic concepts, the second studies the scientific basis for electrode and electrolyte thermodynamics (including E-pH diagrams and the minimum energy involved in transformations) and the kinetics of rate processes (including the energy lost in heat and in parasite reactions). The third part treats larger problems in electrolysis and power generation, as well as in corrosion and its prevention. Each chapter includes three sections: the presentation of useful principles; some twenty problems with their solutions; and, a set of unsolved problems

Classifying IS Project Problems

DEFF Research Database (Denmark)

Munk-Madsen, Andreas

2006-01-01

The literature contains many lists of IS project problems, often in the form of risk factors. The problems sometimes appear unordered and overlapping, which reduces their usefulness to practitioners as well as theoreticians. This paper proposes a list of criteria for formulating project problems...

Time Dependent Heterogeneous Vehicle Routing Problem for Catering Service Delivery Problem

Science.gov (United States)

Azis, Zainal; Mawengkang, Herman

2017-09-01

The heterogeneous vehicle routing problem (HVRP) is a variant of vehicle routing problem (VRP) which describes various types of vehicles with different capacity to serve a set of customers with known geographical locations. This paper considers the optimal service deliveries of meals of a catering company located in Medan City, Indonesia. Due to the road condition as well as traffic, it is necessary for the company to use different type of vehicle to fulfill customers demand in time. The HVRP incorporates time dependency of travel times on the particular time of the day. The objective is to minimize the sum of the costs of travelling and elapsed time over the planning horizon. The problem can be modeled as a linear mixed integer program and we address a feasible neighbourhood search approach to solve the problem.

Reconfigurable layout problem

NARCIS (Netherlands)

Meng, G.; Heragu, S.S.; Heragu, S.S.; Zijm, Willem H.M.

2004-01-01

This paper addresses the reconfigurable layout problem, which differs from traditional, robust and dynamic layout problems mainly in two aspects: first, it assumes that production data are available only for the current and upcoming production period. Second, it considers queuing performance

Personifikacja teorii: gry intertekstualne w „Małym światku"

Directory of Open Access Journals (Sweden)

Magdalena Tymicka

2007-09-01

Full Text Available The paper tries to deal with a relationship between theory and fiction. Reading David Lodge academic novel Small World, where the conflict between structuralism and deconstruction is the plot's main theme, the author asks what happens when theory becomes a subject of a novel. Being a part of fictional discourse, turns out quite tricky for the theoretical discourse, as it could come dangerously close to irony, parody or pastishe. In-depth analysis of complicated narration levels and author's strategy in Lodge's novel is supposed to draw the reader from simple conclusions, in which literature poses an example for theory, or theory for literature. It allows to see the relation between both of these subjects as dynamic and full of contradictions, pointing at, and indicating each other's limitations.

A Problem-Reduction Evolutionary Algorithm for Solving the Capacitated Vehicle Routing Problem

Directory of Open Access Journals (Sweden)

Wanfeng Liu

2015-01-01

Full Text Available Assessment of the components of a solution helps provide useful information for an optimization problem. This paper presents a new population-based problem-reduction evolutionary algorithm (PREA based on the solution components assessment. An individual solution is regarded as being constructed by basic elements, and the concept of acceptability is introduced to evaluate them. The PREA consists of a searching phase and an evaluation phase. The acceptability of basic elements is calculated in the evaluation phase and passed to the searching phase. In the searching phase, for each individual solution, the original optimization problem is reduced to a new smaller-size problem. With the evolution of the algorithm, the number of common basic elements in the population increases until all individual solutions are exactly the same which is supposed to be the near-optimal solution of the optimization problem. The new algorithm is applied to a large variety of capacitated vehicle routing problems (CVRP with customers up to nearly 500. Experimental results show that the proposed algorithm has the advantages of fast convergence and robustness in solution quality over the comparative algorithms.

An algorithm for the split-feasibility problems with application to the split-equality problem.

Science.gov (United States)

Chuang, Chih-Sheng; Chen, Chi-Ming

2017-01-01

In this paper, we study the split-feasibility problem in Hilbert spaces by using the projected reflected gradient algorithm. As applications, we study the convex linear inverse problem and the split-equality problem in Hilbert spaces, and we give new algorithms for these problems. Finally, numerical results are given for our main results.

Non-integrability of the Anisotropic Stormer Problem and the Isosceles Three-Body Problem

Science.gov (United States)

Nomikos, D. G.; Papageorgiou, V. G.

2009-02-01

We study the Anisotropic Stormer Problem (ASP) and the Isosceles Three-Body Problem (IP), from the viewpoint of integrability, using Morales-Ramis theory and its generalization. The study of their integrability presents particular interest since they model important physical phenomena. Both problems can be reduced with respect to the S1 symmetry. Almeida and Stuchi [M.A. Almeida, T.J. Stuchi, Non-integrability of the anisotropic Stormer problem with angular momentum, Physica D 189 (2004) 219-233] proved that the reduced ASP is non-integrable for almost all values of the parameters. In this paper we establish the non-integrability (in the extended Liouville sense) of the remaining cases. The IP is a special case of the three-body problem and it can be considered as a generalization of the Sitnikov problem. Here we prove that the complexified reduced IP does not admit an additional independent meromorphic first integral.

The triangle scheduling problem

NARCIS (Netherlands)

Dürr, Christoph; Hanzálek, Zdeněk; Konrad, Christian; Seddik, Yasmina; Sitters, R.A.; Vásquez, Óscar C.; Woeginger, Gerhard

2017-01-01

This paper introduces a novel scheduling problem, where jobs occupy a triangular shape on the time line. This problem is motivated by scheduling jobs with different criticality levels. A measure is introduced, namely the binary tree ratio. It is shown that the Greedy algorithm solves the problem to

Mechanics problems in undergraduate physics

CERN Document Server

Strelkov, S P

2013-01-01

Problems in Undergraduate Physics, Volume I: Mechanics focuses on solutions to problems in physics. The book first discusses the fundamental problems in physics. Topics include laws of conservation of momentum and energy; dynamics of a point particle in circular motion; dynamics of a rotating rigid body; hydrostatics and aerostatics; and acoustics. The text also offers information on solutions to problems in physics. Answers to problems in kinematics, statics, gravity, elastic deformations, vibrations, and hydrostatics and aerostatics are discussed. Solutions to problems related to the laws of

Simon on problem solving

DEFF Research Database (Denmark)

Foss, Kirsten; Foss, Nicolai Juul

2006-01-01

as a general approach to problem solving. We apply these Simonian ideas to organisational issues, specifically new organisational forms. Specifically, Simonian ideas allow us to develop a morphology of new organisational forms and to point to some design problems that characterise these forms.......Two of Herbert Simon's best-known papers are 'The Architecture of Complexity' and 'The Structure of Ill-Structured Problems.' We discuss the neglected links between these two papers, highlighting the role of decomposition in the context of problems on which constraints have been imposed...

Art as metontological problem

Directory of Open Access Journals (Sweden)

Radovanović Saša Ž.

2014-01-01

Full Text Available The author explains the link between fundamental ontology and metontology in Heidegger's thought. In this context, he raises the question about art as a metontological problem. Then he goes to show that the problem of metontology stems from imanent transformation of fundamental ontology. In this sense, two aspects of the problem of existence assume relevance, namely, universality and radicalism. He draws the conclusion that metontology and art as its problem, as opposed to fundamental ontology, were not integrated into Heidegger's later thought.

Problems in equilibrium theory

CERN Document Server

Aliprantis, Charalambos D

1996-01-01

In studying General Equilibrium Theory the student must master first the theory and then apply it to solve problems. At the graduate level there is no book devoted exclusively to teaching problem solving. This book teaches for the first time the basic methods of proof and problem solving in General Equilibrium Theory. The problems cover the entire spectrum of difficulty; some are routine, some require a good grasp of the material involved, and some are exceptionally challenging. The book presents complete solutions to two hundred problems. In searching for the basic required techniques, the student will find a wealth of new material incorporated into the solutions. The student is challenged to produce solutions which are different from the ones presented in the book.

The three-body problem

International Nuclear Information System (INIS)

Musielak, Z E; Quarles, B

2014-01-01

The three-body problem, which describes three masses interacting through Newtonian gravity without any restrictions imposed on the initial positions and velocities of these masses, has attracted the attention of many scientists for more than 300 years. In this paper, we present a review of the three-body problem in the context of both historical and modern developments. We describe the general and restricted (circular and elliptic) three-body problems, different analytical and numerical methods of finding solutions, methods for performing stability analysis and searching for periodic orbits and resonances. We apply the results to some interesting problems of celestial mechanics. We also provide a brief presentation of the general and restricted relativistic three-body problems, and discuss their astronomical applications. (review article)

Word Problem Wizardry.

Science.gov (United States)

Cassidy, Jack

1991-01-01

Presents suggestions for teaching math word problems to elementary students. The strategies take into consideration differences between reading in math and reading in other areas. A problem-prediction game and four self-checking activities are included along with a magic password challenge. (SM)

On the graph turnpike problem

KAUST Repository

Feder, Tomá s; Motwani, Rajeev

2009-01-01

Results on graph turnpike problem without distinctness, including its NP-completeness, and an O(m+n log n) algorithm, is presented. The usual turnpike problem has all pairwise distances given, but does not specify which pair of vertices w e corresponds to. There are two other problems that can be viewed as special cases of the graph turnpike problem, including the bandwidth problem and the low-distortion graph embedding problem. The aim for the turnpike problem in the NP-complete is to orient the edges with weights w i in either direction so that when the whole cycle is transversed in the real line, it returns to a chosen starting point for the cycle. An instance of the turnpike problem with or without distinctness is uniquely mappable if there exists at most one solution up to translation and choice of orientation.

On the graph turnpike problem

KAUST Repository

Feder, Tomás

2009-06-01

Results on graph turnpike problem without distinctness, including its NP-completeness, and an O(m+n log n) algorithm, is presented. The usual turnpike problem has all pairwise distances given, but does not specify which pair of vertices w e corresponds to. There are two other problems that can be viewed as special cases of the graph turnpike problem, including the bandwidth problem and the low-distortion graph embedding problem. The aim for the turnpike problem in the NP-complete is to orient the edges with weights w i in either direction so that when the whole cycle is transversed in the real line, it returns to a chosen starting point for the cycle. An instance of the turnpike problem with or without distinctness is uniquely mappable if there exists at most one solution up to translation and choice of orientation.

Using Problem-solving Therapy to Improve Problem-solving Orientation, Problem-solving Skills and Quality of Life in Older Hemodialysis Patients.

Science.gov (United States)

Erdley-Kass, Shiloh D; Kass, Darrin S; Gellis, Zvi D; Bogner, Hillary A; Berger, Andrea; Perkins, Robert M

2017-08-24

To determine the effectiveness of Problem-Solving Therapy (PST) in older hemodialysis (HD) patients by assessing changes in health-related quality of life and problem-solving skills. 33 HD patients in an outpatient hemodialysis center without active medical and psychiatric illness were enrolled. The intervention group (n = 15) received PST from a licensed social worker for 6 weeks, whereas the control group (n = 18) received usual care treatment. In comparison to the control group, patients receiving PST intervention reported improved perceptions of mental health, were more likely to view their problems with a positive orientation and were more likely to use functional problem-solving methods. Furthermore, this group was also more likely to view their overall health, activity limits, social activities and ability to accomplish desired tasks with a more positive mindset. The results demonstrate that PST may positively impact mental health components of quality of life and problem-solving coping among older HD patients. PST is an effective, efficient, and easy to implement intervention that can benefit problem-solving abilities and mental health-related quality of life in older HD patients. In turn, this will help patients manage their daily living activities related to their medical condition and reduce daily stressors.

Addressing problems of employee performance.

Science.gov (United States)

McConnell, Charles R

2011-01-01

Employee performance problems are essentially of 2 kinds: those that are motivational in origin and those resulting from skill deficiencies. Both kinds of problems are the province of the department manager. Performance problems differ from problems of conduct in that traditional disciplinary processes ordinarily do not apply. Rather, performance problems are addressed through educational and remedial processes. The manager has a basic responsibility in ensuring that everything reasonable is done to help each employee succeed. There are a number of steps the manager can take to address employee performance problems.

A New Iterative Method for Equilibrium Problems and Fixed Point Problems

Directory of Open Access Journals (Sweden)

Abdul Latif

2013-01-01

Full Text Available Introducing a new iterative method, we study the existence of a common element of the set of solutions of equilibrium problems for a family of monotone, Lipschitz-type continuous mappings and the sets of fixed points of two nonexpansive semigroups in a real Hilbert space. We establish strong convergence theorems of the new iterative method for the solution of the variational inequality problem which is the optimality condition for the minimization problem. Our results improve and generalize the corresponding recent results of Anh (2012, Cianciaruso et al. (2010, and many others.

Morava River floodplain development during the last millennium, Straznicke Pomoravi, Czech Republic

Czech Academy of Sciences Publication Activity Database

Kadlec, Jaroslav; Grygar, Tomáš; Světlík, Ivo; Ettler, V.; Mihaljevič, M.; Diehl, J. F.; Beske-Diehl, S.; Svitavská-Svobodová, Helena

2009-01-01

Roč. 19, č. 3 (2009), s. 499-509 ISSN 0959-6836 R&D Projects: GA AV ČR IAAX00130801; GA AV ČR IAA3013201 Institutional research plan: CEZ:AV0Z30130516; CEZ:AV0Z4032918; CEZ:AV0Z10480505; CEZ:AV0Z60050516 Keywords : floodplain deposits * river activity reconstruction * last millenium * Morava River (Czech Republic) * expandable clay minerals * Cu-trien analysis * mineral magnetic measurements * lead isotope analysis * Holocene fluvial records * land - use change * pollution sources * isotopic-ratios * clay minerals * soil- erosion Subject RIV: DO - Wilderness Conservation Impact factor: 2.481, year: 2009

Data analysis in an Object Request Broker environment

International Nuclear Information System (INIS)

Malon, D.M.; May, E.N.; Grossman, R.L.; Day, C.T.; Quarrie, D.R.

1995-01-01

Computing for the Next Millenium will require software interoperability in heterogeneous, increasingly object-oriented environments. The Common Object Request Broker Architecture (CORBA) is a software industry effort, under the aegis of the Object Management Group (OMG), to standardize mechanisms for software interaction among disparate applications written in a variety of languages and running on a variety of distributed platforms. In this paper, we describe some of the design and performance implications for software that must function in such a brokered environment in a standards-compliant way. We illustrate these implications with a physics data analysis example as a case study

Editorial

Directory of Open Access Journals (Sweden)

Maria de Jesus Fonseca

2016-02-01

Longe estávamos de pensar que afinal esse desejo viria tão cedo a realizar-se! A sua concretização ocorreu dias mais tarde, em 28 de novembro, quando fomos formalmente informados da inclusão da revista no Diretório e no Catálogo LATINDEX1 - Sistema Regional de Información para las Revistas Científicas de América Latina, el Caribe, España y Portugal. Das características exigidas por esta base para nela se ingressar, Millenium cumpre quase todas e muito em breve vai cumpri-las a todas.

Entering the prayer room

DEFF Research Database (Denmark)

Staunæs, Dorthe; Hvenegaard-Lassen, Kirsten

& New York: Routledge. Barad, K. (2007). Meeting the Universe Halfway: Quantum Physics and the Entanglement of Matter and Meaning. Durham: Duke University Press. Haraway, D. (1997). Modest_Witness@Second_Millenium.FemaleMan_Meets_OncoMouse. New York: Routledge. Hvenegård-Lassen, K., & Staunæs, D. (2015......Our main question in this paper concerns how we may investigate the appearance as well as the disappearance of race through the ephemerality of moods. How may the performative effect of mood politics be investigated? How may we explore the non/ephemeral effects of racialized atmospheres and mood...

Getting realistic; Endstation Demut

Energy Technology Data Exchange (ETDEWEB)

Meyer, J.P.

2004-01-28

The fuel cell hype of the turn of the millenium has reached its end. The industry is getting realistic. If at all, fuel cell systems for private single-family and multiple dwellings will not be available until the next decade. With a Europe-wide field test, Vaillant intends to advance the PEM technology. [German] Der Brennstoffzellen-Hype der Jahrtausendwende ist verfolgen. Die Branche uebt sich in Bescheidenheit. Die Marktreife der Systeme fuer Ein- und Mehrfamilienhaeuser wird - wenn ueberhaupt - wohl erst im naechsten Jahrzehnt erreicht sein. Vaillant will durch einen europaweiten Feldtest die Entwicklung der PEM-Technologie vorantreiben. (orig.)

THE PROBLEM OF SUPPLIER

OpenAIRE

Raffo Lecca, Eduardo

2014-01-01

This is a famous problem from the annals of literature in operations research. G. Dantzig in [1] refers to W.W. Jacobs with his paper "The Caterer Problem" Nav. Log Res. Quart. 1 1954; as well as Gaddum, Hoffman and Sokolowsky "On the Solution of the Caterer Problem" Naval Res Logist. Quart., Vol.1, No. 3, september, 1954, and William Prager "On the Caterer Problem" of Management Sci, Vol 3, No. 1 october 1956 and Management Sci, Vol 3, No. 2 january 1957. Subsequently both G. Hadley presents...

The Problem of Evil

OpenAIRE

Araki,Naoki

2018-01-01

The Problem of Evil has been discussed as one of the major problems in monotheism. “Why does Almighty God allow evil to exist?” Various solutions to this problem have been proposed, including the Free Will Defence. But none of them is convincing. The Problem of Evil has an assumption, which is that God exists. One of the proofs of God’s existence is René Descartes’s Ontological Argument. But none of them is persuasive. Every logic has its own assumption, which needs to be verified. So this pr...

Adaptive Problem Solving

Science.gov (United States)

2017-03-01

Borrajo and Raquel Fuentetaja, Universidad Carlos III de Madrid on the meta-level search architecture for finding good combinations of representations and...heuristics on a problem-by-problem basis. The other is with Carlos Linares also from Universidad Carlos III de Madrid on developing effective

Problems in abstract algebra

CERN Document Server

Wadsworth, A R

2017-01-01

This is a book of problems in abstract algebra for strong undergraduates or beginning graduate students. It can be used as a supplement to a course or for self-study. The book provides more variety and more challenging problems than are found in most algebra textbooks. It is intended for students wanting to enrich their learning of mathematics by tackling problems that take some thought and effort to solve. The book contains problems on groups (including the Sylow Theorems, solvable groups, presentation of groups by generators and relations, and structure and duality for finite abelian groups); rings (including basic ideal theory and factorization in integral domains and Gauss's Theorem); linear algebra (emphasizing linear transformations, including canonical forms); and fields (including Galois theory). Hints to many problems are also included.

Calculus problems

CERN Document Server

Baronti, Marco; van der Putten, Robertus; Venturi, Irene

2016-01-01

This book, intended as a practical working guide for students in Engineering, Mathematics, Physics, or any other field where rigorous calculus is needed, includes 450 exercises. Each chapter starts with a summary of the main definitions and results, which is followed by a selection of solved exercises accompanied by brief, illustrative comments. A selection of problems with indicated solutions rounds out each chapter. A final chapter explores problems that are not designed with a single issue in mind but instead call for the combination of a variety of techniques, rounding out the book’s coverage. Though the book’s primary focus is on functions of one real variable, basic ordinary differential equations (separation of variables, linear first order and constant coefficients ODEs) are also discussed. The material is taken from actual written tests that have been delivered at the Engineering School of the University of Genoa. Literally thousands of students have worked on these problems, ensuring their real-...

The Complete Problem Solver.

Science.gov (United States)

Hayes, John R.

This book, designed for a college course on general problem-solving skills, focuses on skills that can be used by anyone in solving problems that occur in everyday life. Part I considers theory and practice: understanding problems, search, and protocol analysis. Part II discusses memory and knowledge acquisition: the structure of human memory,…

Diabetes and Sexual and Urologic Problems

Science.gov (United States)

... Disease, & Other Dental Problems Diabetes, Sexual, & Bladder Problems Diabetes, Sexual, & Bladder Problems Sexual problems and bladder problems ... Can sexual and bladder problems be symptoms of diabetes? Yes. Changes in sexual function or bladder habits ...

Global Arms Trade: Commerce in Advanced Military Technology and Weapons,

Science.gov (United States)

1991-06-01

Indonesia Switzerland Denmark Mexico Nigeria Norway Peru Spain Thailand South Vietnam 1 pi Gray bars indicate developing countries by...Pakistan Philippines Malaysia China Y//////////////M Peru Mexico Madagascar 1{//////A Libya Chile V//////A Algeria Number of systems SOURCE...oflnteramerican Studies and World Affairs, vol. 29, winter 1987-88. 4See Clovis Brigagad, O Mercado do Segwanca: Ensaio Sobre Economia Politico (Rio

Composite gravity and composite supergravity

International Nuclear Information System (INIS)

Lukierski, J.

1982-09-01

It is known that the composite YM H-gauge theory can be constructed from σ-fields taking values in a symmetric Riemannian space G/H. We extend such a framework to graded σ-fields taking values in supercosets. We show that from supercoset σ-fields one can construct composite gravity, and from supercoset σ-superfields the composite supergravity models. (author)

Inhibitory effect of sequential combined chemotherapy and radiotherapy on growth of implanted tumor in mice

International Nuclear Information System (INIS)

Okada, Kouji

1983-01-01

Sequential chemotherapy using FT-207, adriamycin and mitomycin C followed by radiotherapy was attempted to achieve effective inhibition against implanted tumor in C57BL/6 black mice bearing YM-12 tumors. Sequential combined chemotherapy was more effective than single drug chemotherapy or combined chemotherapy of other drugs. Addition of radiotherapy to the sequential combined chemotherapy was successful for enhancing therapeutic effect. (author)

Assessing student written problem solutions: A problem-solving rubric with application to introductory physics

Science.gov (United States)

Docktor, Jennifer L.; Dornfeld, Jay; Frodermann, Evan; Heller, Kenneth; Hsu, Leonardo; Jackson, Koblar Alan; Mason, Andrew; Ryan, Qing X.; Yang, Jie

2016-06-01

Problem solving is a complex process valuable in everyday life and crucial for learning in the STEM fields. To support the development of problem-solving skills it is important for researchers and curriculum developers to have practical tools that can measure the difference between novice and expert problem-solving performance in authentic classroom work. It is also useful if such tools can be employed by instructors to guide their pedagogy. We describe the design, development, and testing of a simple rubric to assess written solutions to problems given in undergraduate introductory physics courses. In particular, we present evidence for the validity, reliability, and utility of the instrument. The rubric identifies five general problem-solving processes and defines the criteria to attain a score in each: organizing problem information into a Useful Description, selecting appropriate principles (Physics Approach), applying those principles to the specific conditions in the problem (Specific Application of Physics), using Mathematical Procedures appropriately, and displaying evidence of an organized reasoning pattern (Logical Progression).

Impact of Context-Rich, Multifaceted Problems on Students' Attitudes Towards Problem-Solving

Science.gov (United States)

Ogilvie, Craig

2008-04-01

Young scientists and engineers need strong problem-solving skills to enable them to address the broad challenges they will face in their careers. These challenges will likely be ill-defined and open-ended with either unclear goals, insufficient constraints, multiple possible solutions, and different criteria for evaluating solutions so that our young scientists and engineers must be able to make judgments and defend their proposed solutions. In contrast, many students believe that problem-solving is being able to apply set procedures or algorithms to tasks and that their job as students is to master an ever-increasing list of procedures. This gap between students' beliefs and the broader, deeper approaches of experts is a strong barrier to the educational challenge of preparing students to succeed in their future careers. To start to address this gap, we have used multi-faceted, context-rich problems in a sophomore calculus-based physics course. To assess whether there was any change in students' attitudes or beliefs towards problem-solving, students were asked to reflect on their problem-solving at the beginning and at the end of the semester. These reflections were coded as containing one or more problem-solving ideas. The change in students' beliefs will be shown in this talk.

Encouraging Sixth-Grade Students' Problem-Solving Performance by Teaching through Problem Solving

Science.gov (United States)

Bostic, Jonathan D.; Pape, Stephen J.; Jacobbe, Tim

2016-01-01

This teaching experiment provided students with continuous engagement in a problem-solving based instructional approach during one mathematics unit. Three sections of sixth-grade mathematics were sampled from a school in Florida, U.S.A. and one section was randomly assigned to experience teaching through problem solving. Students' problem-solving…

Solving applied mathematical problems with Matlab

CERN Document Server

Xue, Dingyu

2008-01-01

Computer Mathematics Language-An Overview. Fundamentals of MATLAB Programming. Calculus Problems. MATLAB Computations of Linear Algebra Problems. Integral Transforms and Complex Variable Functions. Solutions to Nonlinear Equations and Optimization Problems. MATLAB Solutions to Differential Equation Problems. Solving Interpolations and Approximations Problems. Solving Probability and Mathematical Statistics Problems. Nontraditional Solution Methods for Mathematical Problems.

Sturm--Liouville eigenvalue problem

International Nuclear Information System (INIS)

Bailey, P.B.

1977-01-01

The viewpoint is taken that Sturn--Liouville problem is specified and the problem of computing one or more of the eigenvalues and possibly the corresponding eigenfunctions is presented for solution. The procedure follows the construction of a computer code, although such a code is not constructed, intended to solve Sturn--Liouville eigenvalue problems whether singular or nonsingular

Inverse problems of geophysics

International Nuclear Information System (INIS)

Yanovskaya, T.B.

2003-07-01

This report gives an overview and the mathematical formulation of geophysical inverse problems. General principles of statistical estimation are explained. The maximum likelihood and least square fit methods, the Backus-Gilbert method and general approaches for solving inverse problems are discussed. General formulations of linearized inverse problems, singular value decomposition and properties of pseudo-inverse solutions are given

Managing Classroom Problems.

Science.gov (United States)

Long, James D.

Schools need to meet unique problems through the development of special classroom management techniques. Factors which contribute to classroom problems include lack of supervision at home, broken homes, economic deprivation, and a desire for peer attention. The educational atmosphere should encourage creativity for both the student and the…

Numerical problems in physics

CERN Document Server

Singh, Devraj

2015-01-01

Numerical Problems in Physics, Volume 1 is intended to serve the need of the students pursuing graduate and post graduate courses in universities with Physics and Materials Science as subject including those appearing in engineering, medical, and civil services entrance examinations. KEY FEATURES: * 29 chapters on Optics, Wave & Oscillations, Electromagnetic Field Theory, Solid State Physics & Modern Physics * 540 solved numerical problems of various universities and ompetitive examinations * 523 multiple choice questions for quick and clear understanding of subject matter * 567 unsolved numerical problems for grasping concepts of the various topic in Physics * 49 Figures for understanding problems and concept

Combinatorial problems and exercises

CERN Document Server

Lovász, László

2007-01-01

The main purpose of this book is to provide help in learning existing techniques in combinatorics. The most effective way of learning such techniques is to solve exercises and problems. This book presents all the material in the form of problems and series of problems (apart from some general comments at the beginning of each chapter). In the second part, a hint is given for each exercise, which contains the main idea necessary for the solution, but allows the reader to practice the techniques by completing the proof. In the third part, a full solution is provided for each problem. This book w

Problem Gambling Among Ontario Students: Associations with Substance Abuse, Mental Health Problems, Suicide Attempts, and Delinquent Behaviours.

Science.gov (United States)

Cook, Steven; Turner, Nigel E; Ballon, Bruce; Paglia-Boak, Angela; Murray, Robert; Adlaf, Edward M; Ilie, Gabriela; den Dunnen, Wendy; Mann, Robert E

2015-12-01

This paper describes gambling problems among Ontario students in 2009 and examines the relationship between gambling problems and substance use problems, mental health problem indicators, and delinquent behaviors. Data were derived from the Ontario Student Drug Use and Health Survey of Ontario students in grades 7-12. Gambling problems were measured as 2 or more of 6 indicators of problem gambling. In total 2.8% of the students surveyed endorsed two or more of the problem gambling items. The odds of problem gamblers reporting mental distress was 4.2 times higher than the rest of the sample and the odds of problem gamblers reporting a suicide attempt were 17.8 times greater than the rest of the sample. In addition compared to the rest of the students, delinquent behaviors were also more common among problem gamblers, including theft (OR = 14.5), selling marijuana (OR = 19.6), gang fights (OR = 11.3) and carrying a handgun (OR = 11.2). In a multivariate analysis, substance-use problems, mental health problems, and the participation in a variety of delinquent behaviors remained significantly associated with youth problem gambling behavior. Students who report problem gambling behaviors show increased substance abuse, mental health, and delinquency/criminal problems that are similar to those seen among adult problem gamblers. The association between these problems suggests that these problems could be addressed in a unified manner.

Polyhedral combinatorics of the cardinality constrained quadratic knapsack problem and the quadratic selective travelling salesman problem

DEFF Research Database (Denmark)

Mak, Vicky; Thomadsen, Tommy

2006-01-01

This paper considers the cardinality constrained quadratic knapsack problem (QKP) and the quadratic selective travelling salesman problem (QSTSP). The QKP is a generalization of the knapsack problem and the QSTSP is a generalization of the travelling salesman problem. Thus, both problems are NP...

Age differences in everyday problem-solving effectiveness: older adults select more effective strategies for interpersonal problems.

Science.gov (United States)

Blanchard-Fields, Fredda; Mienaltowski, Andrew; Seay, Renee Baldi

2007-01-01

Using the Everyday Problem Solving Inventory of Cornelius and Caspi, we examined differences in problem-solving strategy endorsement and effectiveness in two domains of everyday functioning (instrumental or interpersonal, and a mixture of the two domains) and for four strategies (avoidance-denial, passive dependence, planful problem solving, and cognitive analysis). Consistent with past research, our research showed that older adults were more problem focused than young adults in their approach to solving instrumental problems, whereas older adults selected more avoidant-denial strategies than young adults when solving interpersonal problems. Overall, older adults were also more effective than young adults when solving everyday problems, in particular for interpersonal problems.

Astronauts' menu problem.

Science.gov (United States)

Lesso, W. G.; Kenyon, E.

1972-01-01

Consideration of the problems involved in choosing appropriate menus for astronauts carrying out SKYLAB missions lasting up to eight weeks. The problem of planning balanced menus on the basis of prepackaged food items within limitations on the intake of calories, protein, and certain elements is noted, as well as a number of other restrictions of both physical and arbitrary nature. The tailoring of a set of menus for each astronaut on the basis of subjective rankings of each food by the astronaut in terms of a 'measure of pleasure' is described, and a computer solution to this problem by means of a mixed integer programming code is presented.

Problem situations in management activity

OpenAIRE

N.A. DUBINKO

2009-01-01

This article reviews contemporary methodological and theoretical approaches to the problem situations in management activity. Revealed and analyzed the types of problem situations managers dealing with in their activity. Rank correlation of problem situations shows distinctions depending on management work experience. Revealed gender distinctions in the managers' ideas of management problems.

Reading the problem family: post-structuralism and the analysis of social problems.

Science.gov (United States)

Reekie, G

1994-01-01

Post-structuralist theory questions the rational pursuit of an underlying 'truth' that often characterizes social scientific inquiry, proposing instead the simultaneous existence of multiple and often contradictory truths. The problem family can, from this perspective, only be known through the different discourses that produce it. This paper suggests some of the political advantages of developing methods of reading 'problems' related to drugs and alcohol. Without this critical attention to language, we risk perpetuating the ways in which problems are talked about and thought about. Drawing on examples from debates surrounding teenage pregnancy and youth drinking, the paper argues that post-structuralism allows us to analyse the specific ways in which professional discourses write social problems, and hence to own them and to re-write them.

Sleep problems and daytime problem behaviours in children with intellectual disablity

NARCIS (Netherlands)

Didden, H.C.M.; Korzilius, H.P.L.M.; Aperloo, B. van; Overloon, C. van; Vries, M. de

2002-01-01

BACKGROUND: Sleep problems are common among children with intellectual disability (ID). METHOD: The present study assessed the prevalence of severe sleep problems in a sample of children (n=286) with mild to profound ID who lived at home with their parents(s) in the Netherlands. It also

Population Problem In Egypt As One of The Priority Health Problems ...

African Journals Online (AJOL)

In last decades, Egypt had suffered major socioeconomic consequences of population problem. This had resulted from the high levels of birth rates and the steady decline in death rates and so, a widened demographic gap. Management of population problem of Egypt included: Economic development, developing new ...

Investigasi Kemampuan Problem Solving dan Problem Posing Matematis Mahasiswa Via Pendekatan Realistic

OpenAIRE

Afriansyah, Ekasatya Aldila

2016-01-01

Mathematical problem solving and problem posing skill are the mathematical skills that need to be owned by students. By having this skill, students can be more creative in expressing ideas by connecting the knowledge that they held previously. But in reality, there are some students who are lack of problem solving skill; therefore it is really important to improve learning through appropriate approach. Realistic approach had been chosen as the learning theory to be applied in the class. This ...

Iterative methods for tomography problems: implementation to a cross-well tomography problem

Science.gov (United States)

Karadeniz, M. F.; Weber, G. W.

2018-01-01

The velocity distribution between two boreholes is reconstructed by cross-well tomography, which is commonly used in geology. In this paper, iterative methods, Kaczmarz’s algorithm, algebraic reconstruction technique (ART), and simultaneous iterative reconstruction technique (SIRT), are implemented to a specific cross-well tomography problem. Convergence to the solution of these methods and their CPU time for the cross-well tomography problem are compared. Furthermore, these three methods for this problem are compared for different tolerance values.

A taxonomy of inductive problems.

Science.gov (United States)

Kemp, Charles; Jern, Alan

2014-02-01

Inductive inferences about objects, features, categories, and relations have been studied for many years, but there are few attempts to chart the range of inductive problems that humans are able to solve. We present a taxonomy of inductive problems that helps to clarify the relationships between familiar inductive problems such as generalization, categorization, and identification, and that introduces new inductive problems for psychological investigation. Our taxonomy is founded on the idea that semantic knowledge is organized into systems of objects, features, categories, and relations, and we attempt to characterize all of the inductive problems that can arise when these systems are partially observed. Recent studies have begun to address some of the new problems in our taxonomy, and future work should aim to develop unified theories of inductive reasoning that explain how people solve all of the problems in the taxonomy.

Assessing student written problem solutions: A problem-solving rubric with application to introductory physics

Directory of Open Access Journals (Sweden)

Jennifer L. Docktor

2016-05-01

Full Text Available Problem solving is a complex process valuable in everyday life and crucial for learning in the STEM fields. To support the development of problem-solving skills it is important for researchers and curriculum developers to have practical tools that can measure the difference between novice and expert problem-solving performance in authentic classroom work. It is also useful if such tools can be employed by instructors to guide their pedagogy. We describe the design, development, and testing of a simple rubric to assess written solutions to problems given in undergraduate introductory physics courses. In particular, we present evidence for the validity, reliability, and utility of the instrument. The rubric identifies five general problem-solving processes and defines the criteria to attain a score in each: organizing problem information into a Useful Description, selecting appropriate principles (Physics Approach, applying those principles to the specific conditions in the problem (Specific Application of Physics, using Mathematical Procedures appropriately, and displaying evidence of an organized reasoning pattern (Logical Progression.

Problem Solving and Learning

Science.gov (United States)

Singh, Chandralekha

2009-07-01

One finding of cognitive research is that people do not automatically acquire usable knowledge by spending lots of time on task. Because students' knowledge hierarchy is more fragmented, "knowledge chunks" are smaller than those of experts. The limited capacity of short term memory makes the cognitive load high during problem solving tasks, leaving few cognitive resources available for meta-cognition. The abstract nature of the laws of physics and the chain of reasoning required to draw meaningful inferences makes these issues critical. In order to help students, it is crucial to consider the difficulty of a problem from the perspective of students. We are developing and evaluating interactive problem-solving tutorials to help students in the introductory physics courses learn effective problem-solving strategies while solidifying physics concepts. The self-paced tutorials can provide guidance and support for a variety of problem solving techniques, and opportunity for knowledge and skill acquisition.

The Guderley problem revisited

International Nuclear Information System (INIS)

Ramsey, Scott D.; Kamm, James R.; Bolstad, John H.

2009-01-01

The self-similar converging-diverging shock wave problem introduced by Guderley in 1942 has been the source of numerous investigations since its publication. In this paper, we review the simplifications and group invariance properties that lead to a self-similar formulation of this problem from the compressible flow equations for a polytropic gas. The complete solution to the self-similar problem reduces to two coupled nonlinear eigenvalue problems: the eigenvalue of the first is the so-called similarity exponent for the converging flow, and that of the second is a trajectory multiplier for the diverging regime. We provide a clear exposition concerning the reflected shock configuration. Additionally, we introduce a new approximation for the similarity exponent, which we compare with other estimates and numerically computed values. Lastly, we use the Guderley problem as the basis of a quantitative verification analysis of a cell-centered, finite volume, Eulerian compressible flow algorithm.

Junior High School Students’ Perception about Simple Environmental Problem as an Impact of Problem based Learning

Science.gov (United States)

Tapilouw, M. C.; Firman, H.; Redjeki, S.; Chandra, D. T.

2017-09-01

Environmental problem is a real problem that occur in student’s daily life. Junior high school students’ perception about environmental problem is interesting to be investigated. The major aim of this study is to explore junior high school students’ perception about environmental problems around them and ways to solve the problem. The subject of this study is 69 Junior High School Students from two Junior High School in Bandung. This study use two open ended question. The core of first question is environmental problem around them (near school or house). The core of second question is the way to prevent or to solve the problem. These two question are as an impact of problem based learning in science learning. There are two major findings in this study. The first finding, based on most students’ perception, plastic waste cause an environmental problem. The second finding, environmental awareness can be a solution to prevent environmental pollution. The third finding, most student can classify environmental pollution into land, water and air pollution. We can conclude that Junior High School Students see the environmental problem as a phenomenon and teacher can explore environmental problem to guide the way of preventing and resolving environmental problem.

Shielding benchmark problems, (2)

International Nuclear Information System (INIS)

Tanaka, Shun-ichi; Sasamoto, Nobuo; Oka, Yoshiaki; Shin, Kazuo; Tada, Keiko.

1980-02-01

Shielding benchmark problems prepared by Working Group of Assessment of Shielding Experiments in the Research Committee on Shielding Design in the Atomic Energy Society of Japan were compiled by Shielding Laboratory in Japan Atomic Energy Research Institute. Fourteen shielding benchmark problems are presented newly in addition to twenty-one problems proposed already, for evaluating the calculational algorithm and accuracy of computer codes based on discrete ordinates method and Monte Carlo method and for evaluating the nuclear data used in codes. The present benchmark problems are principally for investigating the backscattering and the streaming of neutrons and gamma rays in two- and three-dimensional configurations. (author)

The effectiveness of problem-based learning on students’ problem solving ability in vector analysis course

Science.gov (United States)

Mushlihuddin, R.; Nurafifah; Irvan

2018-01-01

The student’s low ability in mathematics problem solving proved to the less effective of a learning process in the classroom. Effective learning was a learning that affects student’s math skills, one of which is problem-solving abilities. Problem-solving capability consisted of several stages: understanding the problem, planning the settlement, solving the problem as planned, re-examining the procedure and the outcome. The purpose of this research was to know: (1) was there any influence of PBL model in improving ability Problem solving of student math in a subject of vector analysis?; (2) was the PBL model effective in improving students’ mathematical problem-solving skills in vector analysis courses? This research was a quasi-experiment research. The data analysis techniques performed from the test stages of data description, a prerequisite test is the normality test, and hypothesis test using the ANCOVA test and Gain test. The results showed that: (1) there was an influence of PBL model in improving students’ math problem-solving abilities in vector analysis courses; (2) the PBL model was effective in improving students’ problem-solving skills in vector analysis courses with a medium category.

Pelvic floor muscle problems mediate sexual problems in young adult rape victims.

Science.gov (United States)

Postma, Riemke; Bicanic, Iva; van der Vaart, Huub; Laan, Ellen

2013-08-01

Prior studies have addressed sexual abuse and sexual function in adult women. No studies have focused on the effect of adolescence rape on sexual functioning. To investigate the effect of rape on sexual problems and on pelvic floor problems, as well as the mediating role of pelvic floor problems on sexual problems, in a homogenous group of victims of adolescence rape without a history of childhood sexual, physical, and/or emotional abuse. Sexual functioning and pelvic floor functioning were assessed using self-report questionnaires. In this cross-sectional study, a group of 89 young women aged 18-25 years who were victimized by rape in adolescence was compared with a group of 114 nonvictimized controls. The rape victims were treated for posttraumatic stress disorder (PTSD) 3 years prior to participation in the study. Three years posttreatment, rape victims were 2.4 times more likely to have a sexual dysfunction (lubrication problems and pain) and 2.7 times more likely to have pelvic floor dysfunction (symptoms of provoked vulvodynia, general stress, lower urinary tract, and irritable bowel syndrome) than nonvictimized controls. The relationship between rape and sexual problems was partially mediated by the presence of pelvic floor problems. Rape victims and controls did not differ with regard to sexual activities. Rape victims suffer significantly more from sexual dysfunction and pelvic floor dysfunction when compared with nontraumatized controls, despite the provision of treatment for PTSD. Possibly, physical manifestations of PTSD have been left unaddressed in treatment. Future treatment protocols should consider incorporating (physical or psychological) treatment strategies for sexual dysfunction and/or pelvic floor dysfunction into trauma exposure treatments. © 2013 International Society for Sexual Medicine.

The pear thrips problem

Science.gov (United States)

Bruce L. Parker

1991-01-01

As entomologists, we sometimes like to think of an insect pest problem as simply a problem with an insect and its host. Our jobs would be much easier if that were the case, but of course, it is never that simple. There are many other factors besides the insect, and each one must be fully considered to understand the problem and develop effective management solutions....

Pre-Service Class Teacher' Ability in Solving Mathematical Problems and Skills in Solving Daily Problems

Science.gov (United States)

Aljaberi, Nahil M.; Gheith, Eman

2016-01-01

This study aims to investigate the ability of pre-service class teacher at University of Petrain solving mathematical problems using Polya's Techniques, their level of problem solving skills in daily-life issues. The study also investigates the correlation between their ability to solve mathematical problems and their level of problem solving…

When problem size matters: differential effects of brain stimulation on arithmetic problem solving and neural oscillations.

Directory of Open Access Journals (Sweden)

Bruno Rütsche

Full Text Available The problem size effect is a well-established finding in arithmetic problem solving and is characterized by worse performance in problems with larger compared to smaller operand size. Solving small and large arithmetic problems has also been shown to involve different cognitive processes and distinct electroencephalography (EEG oscillations over the left posterior parietal cortex (LPPC. In this study, we aimed to provide further evidence for these dissociations by using transcranial direct current stimulation (tDCS. Participants underwent anodal (30min, 1.5 mA, LPPC and sham tDCS. After the stimulation, we recorded their neural activity using EEG while the participants solved small and large arithmetic problems. We found that the tDCS effects on performance and oscillatory activity critically depended on the problem size. While anodal tDCS improved response latencies in large arithmetic problems, it decreased solution rates in small arithmetic problems. Likewise, the lower-alpha desynchronization in large problems increased, whereas the theta synchronization in small problems decreased. These findings reveal that the LPPC is differentially involved in solving small and large arithmetic problems and demonstrate that the effects of brain stimulation strikingly differ depending on the involved neuro-cognitive processes.

About an Optimal Visiting Problem

Energy Technology Data Exchange (ETDEWEB)

Bagagiolo, Fabio, E-mail: bagagiol@science.unitn.it; Benetton, Michela [Unversita di Trento, Dipartimento di Matematica (Italy)

2012-02-15

In this paper we are concerned with the optimal control problem consisting in minimizing the time for reaching (visiting) a fixed number of target sets, in particular more than one target. Such a problem is of course reminiscent of the famous 'Traveling Salesman Problem' and brings all its computational difficulties. Our aim is to apply the dynamic programming technique in order to characterize the value function of the problem as the unique viscosity solution of a suitable Hamilton-Jacobi equation. We introduce some 'external' variables, one per target, which keep in memory whether the corresponding target is already visited or not, and we transform the visiting problem in a suitable Mayer problem. This fact allows us to overcome the lacking of the Dynamic Programming Principle for the originary problem. The external variables evolve with a hysteresis law and the Hamilton-Jacobi equation turns out to be discontinuous.

Goals and everyday problem solving: examining the link between age-related goals and problem-solving strategy use.

Science.gov (United States)

Hoppmann, Christiane A; Coats, Abby Heckman; Blanchard-Fields, Fredda

2008-07-01

Qualitative interviews on family and financial problems from 332 adolescents, young, middle-aged, and older adults, demonstrated that developmentally relevant goals predicted problem-solving strategy use over and above problem domain. Four focal goals concerned autonomy, generativity, maintaining good relationships with others, and changing another person. We examined both self- and other-focused problem-solving strategies. Autonomy goals were associated with self-focused instrumental problem solving and generative goals were related to other-focused instrumental problem solving in family and financial problems. Goals of changing another person were related to other-focused instrumental problem solving in the family domain only. The match between goals and strategies, an indicator of problem-solving adaptiveness, showed that young individuals displayed the greatest match between autonomy goals and self-focused problem solving, whereas older adults showed a greater match between generative goals and other-focused problem solving. Findings speak to the importance of considering goals in investigations of age-related differences in everyday problem solving.

IDEAL Problem Solving dalam Pembelajaran Matematika

Directory of Open Access Journals (Sweden)

Eny Susiana

2012-01-01

Full Text Available Most educators agree that problem solving is among the most meaningful and importantkinds of learning and thingking. That is, the central focus of learning and instructionshould be learning to solve problems. There are several warrants supporting that claims.They are authenticity, relevance, problem solving engages deeper learning angtherefore enhances meaning making, and constructed to represent problems (problemsolving is more meaningful. It is the reason why we must provide teaching and learningto make student’s problem solving skill in progress. There are many informationprocessingmodels of problem solving, such as simplified model of the problem-solvingprocess by Gicks, Polya’s problem solving process etc. One of them is IDEAL problemsolving. Each letter of IDEAL is stand for an aspect of thinking that is important forproblem solving. IDEAL is identify problem, Define Goal, Explore possible strategies,Anticipate outcme and Act, and Look back and learn. Using peer interaction andquestion prompt in small group in IDEAL problem solving teaching and Learning canimprove problem solving skill.Kata kunci: IDEAL Problem Solving, Interaksi Sebaya, Pertanyaan Penuntun, KelompokKecil.

Radon: A health problem and a communication problem

International Nuclear Information System (INIS)

Johnson, R.H.

1992-01-01

The US Environmental Protection Agency (USEPA) is making great efforts to alert the American public to the potential health risks of radon in homes. The news media have widely publicized radon as a problem; state and local governments are responding to public alarms; and hundreds of radon open-quotes expertsclose quotes are now offering radon detection and mitigation services. Apparently, USEPA's communication program is working, and the public is becoming increasingly concerned with radon. But are they concerned with radon as a open-quotes healthclose quotes problem in the way USEPA intended? The answer is yes, partly. More and more, however, the concerns are about home resale values. Many homebuyers are now deciding whether to buy on the basis of a single radon screening measurement, comparing it with USEPA's action guide of 4 pCi L -1 . They often conclude that 3.9 is OK, but 4.1 is not. Here is where the communication problems begin. The public largely misunderstands the significance of USEPA's guidelines and the meaning of screening measurements. Seldom does anyone inquire about the quality of the measurements, or the results of USEPA performance testing? Who asks about the uncertainty of lifetime exposure assessments based on a 1-hour, 1-day, 3-day, or even 30-day measurement? Who asks about the uncertainty of USEPA's risk estimates? Fortunately, an increasing number of radiation protection professions are asking such questions. They find that USEPA's risk projections are based on many assumptions which warrant further evaluation, particularly with regard to the combined risks of radon and cigarette-smoking. This is the next communication problem. What are these radiation professions doing to understand the bases for radon health-risk projections? Who is willing to communicate a balanced perspective to the public? Who is willing to communicate the uncertainty and conservatism in radon measurements and risk estimates?

THE ROLE OF DIFFERENT WELL-BEING FORMS IN MARRIAGE SATISFACTION OF PEOPLE AT THE MATURE AGE

Directory of Open Access Journals (Sweden)

N. V. Grisenko

2016-05-01

The sample consisted of 50 married couples aged from 40 to 50. The research participants are Dnipropetrovs’k region citizens. Method. “Marriage satisfaction test” by Yu.Ye. Al’oshina, “Test-questionnaire ‒ Marriage satisfaction” by V. Stolin, “The psychological well-being scale” by K. Riff (adapted by T.D. Shevelenkova & T.P. Fesenko, “Social well-being scale” by K. Kiza (adapted by A.H. Chetveryk-Burchak, “Scale of positive and negative experience” (“The  PANAS  Scales”  by  D.  Watson,  L.  A.  Clark  and  A.  Tellegen  modified  by Y.M. Osin and “The satisfaction with life scale” by E. Diener (adapted by D. Leontiev and Y.M. Osin. Results and conclusion. Positive meaningful correlation between three well-being forms (psychological, subjective and social, their components and marriage satisfaction of people at the mature age was revealed. The research has showed that when basiс needs of a person are satisfied and he finds himself in the state of well-being, it in its turn influences the marriage satisfaction level.

YIELD AND QUALITY OF ‘PERA’ SWEET ORANGE GRAFTED ON DIFFERENT ROOTSTOCKS UNDER RAINFED CONDITIONS

Directory of Open Access Journals (Sweden)

ANTONIO HÉLDER RODRIGUES SAMPAIO

Full Text Available ABSTRACT This study aimed to evaluate, under field conditions, different combinations between ‘Pera’ sweet orange and eight rootstocks: ‘Rangpur’ lime (RL, ‘Volkamer’ lemon (VL, ‘Cleopatra’ mandarin (CM, ‘Sunki Maravilha’ mandarin (SMM, ‘Indio’ and ‘Riverside’ citrandarins, and VL x RL (‘Rangpur’ lime-010 and TH-051 hybrids. The soil water matric potential (?m was characterized for all scion-rootstock combinations at distance of 1.0m from the trunk at the plant row direction and depths of 0.25 m, 0.50 m 0.90 m in the dry and wet seasons. For two years, fruit production parameters and fruit quality were assessed. Differences of Ym among scion-rootstock combinations were observed during the dry season (p=0.05. The lowest Ym values for RL and the highest for TH-051 indicate the existence of different intrinsic mechanisms affecting the water extraction of each scion-rootstock combination. Rootstocks have influenced fruit yield and quality (p=0.05. The best combinations for fruit quality and production were sweet orange grafted on ‘Riverside’, ‘Indio’ and TH-051 rootstocks.

A novel malic enzyme gene, Mime2, from Mortierella isabellina M6-22 contributes to lipid accumulation.

Science.gov (United States)

Li, Shan; Li, Lingyan; Xiong, Xiangfeng; Ji, Xiuling; Wei, Yunlin; Lin, Lianbing; Zhang, Qi

2018-05-18

This study was aimed at cloning and characterizing a novel malic enzyme (ME) gene of Mortierella isabellina M6-22 and identifying its relation with lipid accumulation. Mime2 was cloned from strain M6-22. Plasmid pET32aMIME2 was constructed to express ME of MIME2 in Escherichia coli BL21. After purification, the optimal pH and temperature of MIME2, as well as K m and V max for NADP + were determined. The effects of EDTA or metal ions (Mn 2+ , Mg 2+ , Co 2+ , Cu 2+ , Ca 2+ , or Zn 2+ ) on the enzymatic activity of MIME2 were evaluated. Besides, plasmid pRHMIME2 was created to express MIME2 in Rhodosporidium kratochvilovae YM25235, and its cell lipid content was measured by the acid-heating method. The optimal pH and temperature of MIME2 are 5.8 and 30 °C, respectively. The act ivity of MIME2 was significantly increased by Mg 2+ , Ca 2+ , or Mn 2+ at 0.5 mM but inhibited by Cu 2+ or Zn 2+ (p M6-22 contributes to lipid accumulation in strain YM25235.

Biochemical Contributions to Corrosion of Carbon Steel and Alloy 22 in a Continual Flow System

International Nuclear Information System (INIS)

Horn, J.; Martin, S.; Masterson, B.; Lian, T.

1998-01-01

Microbiologically influenced corrosion (MIC) may decrease the functional lifetime of nuclear waste packaging materials in the potential geologic repository at Yucca Mountain (YM), Nevada. Biochemical contributions to corrosion of package materials are being determined in reactors containing crushed repository-site rock with the endogenous microbial community, and candidate waste package materials. These systems are being continually supplied with simulated ground water. Periodically, bulk chemistries are analyzed on the system outflow, and surfacial chemistries are assessed on withdrawn material coupons. Both Fe and Mn dissolved from C1020 coupons under conditions that included the presence of YM microorganisms. Insoluble corrosion products remained in a reduced state at the coupon surface, indicating at least a localized anoxic condition; soluble reduced Mn and Fe were also detected in solution, while precipitated and spalled products were oxidized. Alloy 22 surfaces showed a layer of chrome oxide, almost certainly in the Cr(III) oxidation state, on microcosm-exposed coupons, while no soluble chrome was detected in solution. The results of these studies will be compared to identical testing on systems containing sterilized rock to generate, and ultimately predict, microbial contributions to waste package corrosion chemistries

A novel integrated process of coal pyrolysis and methane CO{sub 2} reforming

Energy Technology Data Exchange (ETDEWEB)

Jing Wang; Pengfei Wang; Lijun Jin; Haoquan Hu [Dalian University of Technology, Dalian (China)

2007-07-01

In the paper, a novel pyrolysis method, namely coal pyrolysis coupling with CO{sub 2} reforming of methane (CRMP) or catalytic pyrolysis of coal coupling with CO{sub 2} reforming of methane (CRMCP), for improving the tar yield of coal pyrolysis was introduced. The behaviours of YM coal in both processes were investigated and compared with pyrolysis under N{sub 2} and H{sub 2}. The results show that the tar yield of coal pyrolysis in both processes obviously increase compared with that in N{sub 2} or H{sub 2}. When YM coal pyrolysis was carried out in stream of mixture gas CH{sub 4}/CO{sub 2} (1:1) with the existence of the catalyst at 0.1 MPa and 800{sup o}C, the tar yield is 2.8 times for CRMP and 4.3 times for CRMCP as that of pyrolysis under N{sub 2} and 1.7 and 2.6 times as that of hydropyrolysis at the same conditions, respectively. Sulfur content of char obtained from CRMP and CRMCP process are lower, especially in CRMP process, than that from N{sub 2} or H{sub 2}. 16 refs., 4 figs., 1 tab.

Role of killer factors in the inhibitory activity of bio-control yeasts against Penicillium expansum and Aspergillus ochraceus

Directory of Open Access Journals (Sweden)

Ciro da Silva Portes

2013-08-01

Full Text Available This work evaluated the antagonism of killer positive yeast strains (isolated from 11 samples of different frozen fruit pulps against the strains of Penicillium expansum and Aspergillus ochraceus. Of the total 41 killer yeasts tested in YM agar, 19 showed antibiosis against P. expansum and A. ochraceus, with inhibition zone ranging from 10 to 18 mm and 10 to 19 mm, respectively. In the following step, the extracellular activity of Kluyveromyces sp. FP4(13 was tested performing the assay in YM broth. The antifungal activity of Kluyveromyces sp. FP4(13 cell-free culture supernatant (25ºC/96 h was more effective against the conidia germination, showing inhibition rates of 93.33 and 86.44% for P. expansum and A. ochraceus, respectively. The micelial growth inhibition was 28.45 and 21.0%, respectively. The antagonism showed by the selected yeasts could be used as a promising alternative tool to reduce and control the postharvest fungal spoilage of the fruits. However, further studies should be carried out in order to better elucidate the role of innocuous characters in antagonistic microorganisms, as well as the purification and characterization of new killer toxins.

Advances in Computational High-Resolution Mechanical Spectroscopy HRMS Part I: Logarithmic Decrement

International Nuclear Information System (INIS)

Majewski, M; Magalas, L B; Piłat, A

2012-01-01

The comparison between different methods used to compute the logarithmic decrement in high-resolution mechanical spectroscopy (HRMS) is analyzed. The performance of parametric OMI method (Optimization in Multiple Intervals) and interpolated discrete Fourier transform (IpDFT) methods are investigated as a function of the sampling frequency used to digitize free decaying oscillations in low-frequency resonant mechanical spectrometers. It is clearly demonstrated that a new Yoshida-Magalas (YM) method is the most powerful IpDFT-based method which outperforms the standard Yoshida (Y) method and other DFT-based methods. Four IpDFT methods and the OMI method are carefully analyzed as a function of the sampling frequency. The results presented in this work clearly show that the relative error in the estimation of the logarithmic decrement depends both on the length of free decaying signal and on the sampling frequency. The effect of the sampling frequency was not yet reported in the literature. The performance of different methods used in the computations of the logarithmic decrement can be listed in the following order: (1) the OMI, (2) the Yoshida-Magalas YM, (3) the Yoshida-Magalas YMC, and finally (4) the Yoshida Y.

Advances in Computational High-Resolution Mechanical Spectroscopy HRMS Part II: Resonant Frequency – Young's Modulus

International Nuclear Information System (INIS)

Majewski, M; Magalas, L B

2012-01-01

In this paper, we compare the values of the resonant frequency f 0 of free decaying oscillations computed according to the parametric OMI method (Optimization in Multiple Intervals) and nonparametric DFT-based (discrete Fourier transform) methods as a function of the sampling frequency. The analysis is carried out for free decaying signals embedded in an experimental noise recorded for metallic samples in a low-frequency resonant mechanical spectrometer. The Yoshida method (Y), the Agrez' method (A), and new interpolated discrete Fourier transform (IpDFT) methods, that is, the Yoshida-Magalas (YM) and (YM C ) methods developed by the authors are carefully compared for the resonant frequency f 0 = 1.12345 Hz and the logarithmic decrement, δ = 0.0005. Precise estimation of the resonant frequency (Youngs' modulus ∼ f 0 2 ) for real experimental conditions, i.e., for exponentially damped harmonic signals embedded in an experimental noise, is a complex task. In this work, various computing methods are analyzed as a function of the sampling frequency used to digitize free decaying oscillations. The importance of computing techniques to obtain reliable and precise values of the resonant frequency (i.e. Young's modulus) in materials science is emphasized.

Influence of fluorescent dye on physical-mechanical properties of luting cements for confocal microscopy analysis.

Science.gov (United States)

Oliveira, Dayane; Prieto, Lúcia; Araújo, Cíntia; Coppini, Erick; Pereira, Gisele; Paulillo, Luís

2014-12-01

To evaluate the influence of a fluorescent dye (rhodamine B) on the physical and mechanical properties of three different luting cements: a conventional adhesive luting cement (RelyX ARC, 3M/ESPE), a self-adhesive luting cement (RelyX U-200, 3M/ESPE), and a self-etching and self-adhesive luting cement (SeT PP, SDI). The cements were mixed with 0.03 wt% rhodamine B, formed into bar-shaped specimens (n = 10), and light cured using an LED curing unit (Radii, SDI) with a radiant exposure of 32 J/cm(2) . The Knoop hardness (KHN), flexural strength (FS), and Young's modulus (YM) analyses were evaluated after storage for 24 h. Outcomes were subjected to two-way ANOVA and Tukey's test (P = 0.05) for multiple comparisons. No significant differences in FS or YM were observed among the tested groups (P ≥ 0.05); the addition of rhodamine B increased the hardness of the luting cements tested. The addition of a fluorescent agent at 0.03 wt% concentration does not negatively affect the physical-mechanical properties of the luting cement polymerization behavior. © 2014 Wiley Periodicals, Inc.

Yucca Mountain near-field environment considerations for engineered barrier system design and performance

International Nuclear Information System (INIS)

Wilder, D.G.

1991-05-01

The United States Department of Energy (DOE) is investigating the suitability of Yucca Mountain (YM) as a potential site for the nation's first High-Level Nuclear Waste Repository. This responsibility includes materials testing and selections, design criteria development, waste form characterizations, performance assessments, and Near-Field (NF) environment characterization. These areas of responsibility are interrelated and to a large extent depend on environmental conditions surrounding the EBS components. The focus of this paper is to discuss what is currently known about the NF environment, particularly those aspects whose interaction with EBS components have significant impacts on the performance of the EBS and its ability to contribute to the isolation of radioactive waste. Reference designs and design/processes assumptions are used to evaluate the expected NF environmental conditions. This report will not focus on providing parameter values but rather on the processes that influence those parameters and on the impacts of those parameters on the performance of EBS components. Where values are given, they should be viewed as typical of YM as a whole but not necessarily representative of the actual NF environment conditions that surround the EBS components. 19 refs., 6 figs

Using Problem-Based Learning in Accounting

Science.gov (United States)

Hansen, James D.

2006-01-01

In this article, the author describes the process of writing a problem-based learning (PBL) problem and shows how a typical end-of-chapter accounting problem can be converted to a PBL problem. PBL uses complex, real-world problems to motivate students to identify and research the concepts and principles they need to know to solve these problems.…

GREECE--SELECTED PROBLEMS.

Science.gov (United States)

MARTONFFY, ANDREA PONTECORVO; AND OTHERS

A CURRICULUM GUIDE IS PRESENTED FOR A 10-WEEK STUDY OF ANCIENT GREEK CIVILIZATION AT THE 10TH-GRADE LEVEL. TEACHING MATERIALS FOR THE UNIT INCLUDE (1) PRIMARY AND SECONDARY SOURCES DEALING WITH THE PERIOD FROM THE BRONZE AGE THROUGH THE HELLENISTIC PERIOD, (2) GEOGRAPHY PROBLEMS, AND (3) CULTURAL MODEL PROBLEM EXERCISES. THOSE CONCEPTS WITH WHICH…

How to solve mathematical problems

CERN Document Server

Wickelgren, Wayne A

1995-01-01

Seven problem-solving techniques include inference, classification of action sequences, subgoals, contradiction, working backward, relations between problems, and mathematical representation. Also, problems from mathematics, science, and engineering with complete solutions.

Problem Solving Instruction for Overcoming Students' Difficulties in Stoichiometric Problems

Science.gov (United States)

Shadreck, Mandina; Enunuwe, Ochonogor Chukunoye

2017-01-01

The study sought to find out difficulties encountered by high school chemistry students when solving stoichiometric problems and how these could be overcome by using a problem-solving approach. The study adopted a quasi-experimental design. 485 participants drawn from 8 highs schools in a local education district in Zimbabwe participated in the…

Parentification, Stress, and Problem Behavior of Adolescents who have a Parent with Mental Health Problems.

Science.gov (United States)

Van Loon, Linda M A; Van de Ven, Monique O M; Van Doesum, Karin T M; Hosman, Clemens M H; Witteman, Cilia L M

2017-03-01

When adolescents live with a parent with mental illness, they often partly take over the parental role. Little is known about the consequences of this so-called parentification on the adolescents' internalizing and externalizing problems. This survey study examined this effect cross-sectionally and longitudinally in a sample of 118 adolescents living with a parent suffering from mental health problems. In addition, the study examined a possible indirect effect via perceived stress. Path analyses were used to examine the direct associations between parentification and problem behavior as well as the indirect relations via perceived stress. The results showed that parentification was associated with both internalizing and externalizing problems cross-sectionally, but it predicted only internalizing problems 1 year later. An indirect effect of parentification on adolescent internalizing and externalizing problems via perceived stress was found, albeit only cross-sectionally. These findings imply that parentification can be stressful for adolescents who live with a parent with mental health problems, and that a greater awareness of parentification is needed to prevent adolescents from developing internalizing problems. © 2015 Family Process Institute.

Not your problem? Exploring the relationship between problem formulation and social responsibility

Directory of Open Access Journals (Sweden)

Sveinung Jørgensen

2011-05-01

Full Text Available This article explores the relationship between organizationalproblem formulation and social responsibility. Thepurpose of the article is to illuminate how organizationalproblem formulations (1 determine the manner in whichthe organization attempts to solve the problem and (2involve the ascription of significance to a group of stakeholdersseen as relevant for the organization. This has implicationsfor the degree to which they assume responsibilityfor those stakeholders. We discuss three dimensions ofresponsible decision making – rationality in goal attainment,reverence for ethical norms, and respect for stakeholders.Thereby, we arrive at an understanding of how differentorganizations in the same sector conceive of, andattempt to solve fundamental problems in the sector, aswell as how their assumed responsibility is reflected therein.We present and discuss a case that discusses keysimilarities and differences between two organizations inthe drug sector – a pharmaceutical company that producesmedicine for the treatment of drug addiction and a foundationworking with drug rehabilitation. We illuminatehow the two organizations base their activities on divergentformulations of the drug problem and how this ismanifested in their approach to the problem. We argue that this ultimately translates into differences in the inclusion of various stakeholdersin their problem space, and thereby the degree to which they assumeresponsibility for key stakeholders. This contributes to the corporate socialresponsibility literature by providing an in depth account of how problem formulationsshape organizational activities and determine the practical inclusionof stakeholders’ interests in the decisions and activities of organizations.

Problem-Based Learning and Problem-Solving Tools: Synthesis and Direction for Distributed Education Environments.

Science.gov (United States)

Friedman, Robert S.; Deek, Fadi P.

2002-01-01

Discusses how the design and implementation of problem-solving tools used in programming instruction are complementary with both the theories of problem-based learning (PBL), including constructivism, and the practices of distributed education environments. Examines how combining PBL, Web-based distributed education, and a problem-solving…

The stochastic goodwill problem

OpenAIRE

Marinelli, Carlo

2003-01-01

Stochastic control problems related to optimal advertising under uncertainty are considered. In particular, we determine the optimal strategies for the problem of maximizing the utility of goodwill at launch time and minimizing the disutility of a stream of advertising costs that extends until the launch time for some classes of stochastic perturbations of the classical Nerlove-Arrow dynamics. We also consider some generalizations such as problems with constrained budget and with discretionar...

Petrotyranny

Energy Technology Data Exchange (ETDEWEB)

Bacher, J.

2000-07-01

'Petrotyranny' is a concept employed here to describe the role crude oil has come to play in the modern world, creating dictatorial regimes, stirring up civil strife, generating wars among nations, and guiding empires in their policies of domination. The book is concerned with the inner connections between the politics of injustice and oppression practiced throughout the world, made possible by the enormous economic power conferred by the possession of oil resources. The book is a no holds-barred description of how the influence of the fossil fuel industry crushes democratic rights and freedoms in all parts of the world, and prevents any meaningful action on reducing greenhouse gas emissions, dooming future generations to deal with problems that will be far more intractable and far more expensive to deal with than if action were taken immediately. It also highlights a new urgency to move away from fossil fuels and change to reliance on renewable energy sources. It warns that the threat of petrotyranny, war, and dictatorship (dubbed the 'holy trinity') presents the greatest challenge to humanity at the beginning of the new millenium, and demonstrates in a compelling way that the challenge of democratic peace is connected to global energy policies everywhere. References at the end of each chapter.

Petrotyranny

International Nuclear Information System (INIS)

Bacher, J.

2000-01-01

'Petrotyranny' is a concept employed here to describe the role crude oil has come to play in the modern world, creating dictatorial regimes, stirring up civil strife, generating wars among nations, and guiding empires in their policies of domination. The book is concerned with the inner connections between the politics of injustice and oppression practiced throughout the world, made possible by the enormous economic power conferred by the possession of oil resources. The book is a no holds-barred description of how the influence of the fossil fuel industry crushes democratic rights and freedoms in all parts of the world, and prevents any meaningful action on reducing greenhouse gas emissions, dooming future generations to deal with problems that will be far more intractable and far more expensive to deal with than if action were taken immediately. It also highlights a new urgency to move away from fossil fuels and change to reliance on renewable energy sources. It warns that the threat of petrotyranny, war, and dictatorship (dubbed the 'holy trinity') presents the greatest challenge to humanity at the beginning of the new millenium, and demonstrates in a compelling way that the challenge of democratic peace is connected to global energy policies everywhere. References at the end of each chapter

Petrotyranny

Energy Technology Data Exchange (ETDEWEB)

Bacher, J

2000-07-01

'Petrotyranny' is a concept employed here to describe the role crude oil has come to play in the modern world, creating dictatorial regimes, stirring up civil strife, generating wars among nations, and guiding empires in their policies of domination. The book is concerned with the inner connections between the politics of injustice and oppression practiced throughout the world, made possible by the enormous economic power conferred by the possession of oil resources. The book is a no holds-barred description of how the influence of the fossil fuel industry crushes democratic rights and freedoms in all parts of the world, and prevents any meaningful action on reducing greenhouse gas emissions, dooming future generations to deal with problems that will be far more intractable and far more expensive to deal with than if action were taken immediately. It also highlights a new urgency to move away from fossil fuels and change to reliance on renewable energy sources. It warns that the threat of petrotyranny, war, and dictatorship (dubbed the 'holy trinity') presents the greatest challenge to humanity at the beginning of the new millenium, and demonstrates in a compelling way that the challenge of democratic peace is connected to global energy policies everywhere. References at the end of each chapter.

The interpretation of archaeological dates from an AMS perspective

International Nuclear Information System (INIS)

Zoppi, U.; Sagona, A.; Siegele, R.; Hua, Q.; Jacobsen, G.; Lawson, E.M.

2001-01-01

The XVII century saw the establishment of the scientific method and scholars such as Galileo were giving excellent contributions to a variety of fields ranging from the natural sciences to the humanities. At the dawn of the new millenium, after a period of excessive specialization, the scientific climate is once again encouraging broad collaborations across different disciplines. For projects involving AMS measurements in general and radiocarbon dating in particular, the benefits of this new trend are numerous. For example, the full potential of the radiocarbon dating method can be exploited only through the mutual understanding of the problems related to sample selection, chemical preparation, AMS measurement, data analysis and interpretation. This paper is intended to enhance the exchange of information by reporting to our current and potential collaborators about the latest technical developments undertaken at the ANTARES AMS facility at ANSTO. Furthermore, we will present two splendid examples of collaborative research: the radiocarbon dating of a replica of a famous chesspiece and the archaeological investigations at the ancient settlement of Sos Hoyuk (north-eastern Anatolia, Turkey) where the multidisciplinary approach was the key to a better understanding of the social structure, settlement patterns, land use and cultural contact, especially with the lands of Trans-Caucasus. (author). 12 refs., 4 figs

Problem Based Learning

DEFF Research Database (Denmark)

de Graaff, Erik; Guerra, Aida

, the key principles remain the same everywhere. Graaff & Kolmos (2003) identify the main PBL principles as follows: 1. Problem orientation 2. Project organization through teams or group work 3. Participant-directed 4. Experiental learning 5. Activity-based learning 6. Interdisciplinary learning and 7...... model and in general problem based and project based learning. We apply the principle of teach as you preach. The poster aims to outline the visitors’ workshop programme showing the results of some recent evaluations.......Problem-Based Learning (PBL) is an innovative method to organize the learning process in such a way that the students actively engage in finding answers by themselves. During the past 40 years PBL has evolved and diversified resulting in a multitude in variations in models and practices. However...

Common Sleep Problems (For Teens)

Science.gov (United States)

... Safe Videos for Educators Search English Español Common Sleep Problems KidsHealth / For Teens / Common Sleep Problems What's ... have emotional problems, like depression. What Happens During Sleep? You don't notice it, of course, but ...

JIT-transportation problem and its algorithm

Science.gov (United States)

Bai, Guozhong; Gan, Xiao-Xiong

2011-12-01

This article introduces the (just-in-time) JIT-transportation problem, which requires that all demanded goods be shipped to their destinations on schedule, at a zero or minimal destination-storage cost. The JIT-transportation problem is a special goal programming problem with discrete constraints. This article provides a mathematical model for such a transportation problem and introduces the JIT solution, the deviation solution, the JIT deviation, etc. By introducing the B(λ)-problem, this article establishes the equivalence between the optimal solutions of the B(λ)-problem and the optimal solutions of the JIT-transportation problem, and then provides an algorithm for the JIT-transportation problems. This algorithm is proven mathematically and is also illustrated by an example.

Perturbed asymptotically linear problems

OpenAIRE

Bartolo, R.; Candela, A. M.; Salvatore, A.

2012-01-01

The aim of this paper is investigating the existence of solutions of some semilinear elliptic problems on open bounded domains when the nonlinearity is subcritical and asymptotically linear at infinity and there is a perturbation term which is just continuous. Also in the case when the problem has not a variational structure, suitable procedures and estimates allow us to prove that the number of distinct crtitical levels of the functional associated to the unperturbed problem is "stable" unde...

Adaptive Immune Responses Regulate the Pathophysiology of Lymphedema

Science.gov (United States)

2012-09-01

A, Hennig B (2000) Effect of complex decongestive physiotherapy on gene expression for the inflammatory response in peripheral lymphedema. Lymphology...pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma. Arthritis Rheum 63: 1405-1415. 51. Romani L, Mencacci A, Grohmann...severe disease in collagen-induced arthritis . Arthritis Rheum 48: 1452-1460. 29. Nakamura K, Radhakrishnan K, Wong YM, Rockson SG (2009) Anti

Liiketoimintasuunnitelman laatiminen lounaskahvilaan

OpenAIRE

Mannermaa, Tiina

2015-01-01

Opinnäytetyön aiheena on laatia liiketoimintasuunnitelma lounaskahvilaan, joka sijaitsee kauppakeskuksessa. Liiketoimintasuunnitelma laaditaan omaa käyttöä varten ja se on osittain jatkoa koulutuksessa käymälleni tuotekehityksen kurssille, josta sain inspiraatiota liikeidealleni, millaisen lounaskahvilan haluaisin perustaa. Opinnäytetyön tarkoitus on tehdä liikeidean pohjalta liiketoimintasuunnitelma ja kannattavuuslaskelmat, joiden on tarkoitus antaa suuntaa, kannattaako yritystä perustaa. ...

Rakennusliikkeen liiketoimintasuunnitelma

OpenAIRE

Heikkilä, Markus

2015-01-01

Opinnäytetyön tavoitteena oli laatia toimivan rakennusliikkeen liiketoimintasuunnitelma. Suunnitelmaa pidettiin ajankohtaisena, koska kohdeyrityksessä ollaan käymässä läpi sukupolvenvaihdosta. Työn alussa lähdekirjallisuuden pohjalta tehtiin kirjallisuuskatsaus liittyen liikentoimintasuunnitelmaan ja sen muodostamiseen. Tämän pohjalta toiminnassa olevalle rakennusliikkeelle laadittiin uusi liiketoimintasuunnitelma. Liiketoimintasuunnitelmassa käytiin läpi yrityksen tavoitteet ja keinot nii...

Population Based Assessment of MHC Class I Antigens Down Regulation as Markers of Increased Risk for Development and Progression of Breast Cancer from Benign Breast Lesions

Science.gov (United States)

2007-01-01

Orchid Diagnostics Europe, St Katelijne Waver, Belgium). Sequence based typing In cases were complete HLA-losses on tumor cells were detected by...Centricon YM-100 filters (Millipore, Brussels, Belgium) and visualized in agarose gel electrophoresis using ethidiumbromide to show the single 2 KB band ...reaction for simultaneous screening of 29 translocations and chromosomal aberrations in acute leukemia. Blood. 1998;92:574-588. 22. Gao L, Bellantuono

Students’ difficulties in probabilistic problem-solving

Science.gov (United States)

Arum, D. P.; Kusmayadi, T. A.; Pramudya, I.

2018-03-01

There are many errors can be identified when students solving mathematics problems, particularly in solving the probabilistic problem. This present study aims to investigate students’ difficulties in solving the probabilistic problem. It focuses on analyzing and describing students errors during solving the problem. This research used the qualitative method with case study strategy. The subjects in this research involve ten students of 9th grade that were selected by purposive sampling. Data in this research involve students’ probabilistic problem-solving result and recorded interview regarding students’ difficulties in solving the problem. Those data were analyzed descriptively using Miles and Huberman steps. The results show that students have difficulties in solving the probabilistic problem and can be divided into three categories. First difficulties relate to students’ difficulties in understanding the probabilistic problem. Second, students’ difficulties in choosing and using appropriate strategies for solving the problem. Third, students’ difficulties with the computational process in solving the problem. Based on the result seems that students still have difficulties in solving the probabilistic problem. It means that students have not able to use their knowledge and ability for responding probabilistic problem yet. Therefore, it is important for mathematics teachers to plan probabilistic learning which could optimize students probabilistic thinking ability.

Could HPS Improve Problem-Solving?

Science.gov (United States)

Coelho, Ricardo Lopes

2013-05-01

It is generally accepted nowadays that History and Philosophy of Science (HPS) is useful in understanding scientific concepts, theories and even some experiments. Problem-solving strategies are a significant topic, since students' careers depend on their skill to solve problems. These are the reasons for addressing the question of whether problem solving could be improved by means of HPS. Three typical problems in introductory courses of mechanics—the inclined plane, the simple pendulum and the Atwood machine—are taken as the object of the present study. The solving strategies of these problems in the eighteenth and nineteenth century constitute the historical component of the study. Its philosophical component stems from the foundations of mechanics research literature. The use of HPS leads us to see those problems in a different way. These different ways can be tested, for which experiments are proposed. The traditional solving strategies for the incline and pendulum problems are adequate for some situations but not in general. The recourse to apparent weights in the Atwood machine problem leads us to a new insight and a solving strategy for composed Atwood machines. Educational implications also concern the development of logical thinking by means of the variety of lines of thought provided by HPS.

Teaching problem solving: Don't forget the problem solver(s)

Science.gov (United States)

Ranade, Saidas M.; Corrales, Angela

2013-05-01

The importance of intrapersonal and interpersonal intelligences has long been known but educators have debated whether to and how to incorporate those topics in an already crowded engineering curriculum. In 2010, the authors used the classroom as a laboratory to observe the usefulness of including selected case studies and exercises from the fields of neurology, artificial intelligence, cognitive sciences and social psychology in a new problem-solving course. To further validate their initial findings, in 2012, the authors conducted an online survey of engineering students and engineers. The main conclusion is that engineering students will benefit from learning more about the impact of emotions, culture, diversity and cognitive biases when solving problems. Specifically, the work shows that an augmented problem-solving curriculum needs to include lessons on labelling emotions and cognitive biases, 'evidence-based' data on the importance of culture and diversity and additional practice on estimating conditional probability.

The Steiner tree problem

CERN Document Server

Hwang, FK; Winter, P

1992-01-01

The Steiner problem asks for a shortest network which spans a given set of points. Minimum spanning networks have been well-studied when all connections are required to be between the given points. The novelty of the Steiner tree problem is that new auxiliary points can be introduced between the original points so that a spanning network of all the points will be shorter than otherwise possible. These new points are called Steiner points - locating them has proved problematic and research has diverged along many different avenues. This volume is devoted to the assimilation of the rich field of intriguing analyses and the consolidation of the fragments. A section has been given to each of the three major areas of interest which have emerged. The first concerns the Euclidean Steiner Problem, historically the original Steiner tree problem proposed by Jarník and Kössler in 1934. The second deals with the Steiner Problem in Networks, which was propounded independently by Hakimi and Levin and has enjoyed the most...

Assessing Student Written Problem Solutions: A Problem-Solving Rubric with Application to Introductory Physics

Science.gov (United States)

Docktor, Jennifer L.; Dornfeld, Jay; Frodermann, Evan; Heller, Kenneth; Hsu, Leonardo; Jackson, Koblar Alan; Mason, Andrew; Ryan, Qing X.; Yang, Jie

2016-01-01

Problem solving is a complex process valuable in everyday life and crucial for learning in the STEM fields. To support the development of problem-solving skills it is important for researchers and curriculum developers to have practical tools that can measure the difference between novice and expert problem-solving performance in authentic…

Obstacle mean-field game problem

KAUST Repository

Gomes, Diogo A.; Patrizi, Stefania

2015-01-01

In this paper, we introduce and study a first-order mean-field game obstacle problem. We examine the case of local dependence on the measure under assumptions that include both the logarithmic case and power-like nonlinearities. Since the obstacle operator is not differentiable, the equations for first-order mean field game problems have to be discussed carefully. Hence, we begin by considering a penalized problem. We prove this problem admits a unique solution satisfying uniform bounds. These bounds serve to pass to the limit in the penalized problem and to characterize the limiting equations. Finally, we prove uniqueness of solutions. © European Mathematical Society 2015.

Side Effects: Sleep Problems

Science.gov (United States)

Sleep problems are a common side effect during cancer treatment. Learn how a polysomnogram can assess sleep problems. Learn about the benefits of managing sleep disorders in men and women with cancer.

Mekh-mat entrance examinations problems

CERN Document Server

Vardi, I

2000-01-01

This paper provides a complete solution set to 25 ``killer problems'' given to Jewish candidates to the Mekh--mat at Moscow State University during the 1970's and 1980's. Typically, the problems are at the mathematical olympiad level and some feature interesting theorems. However, a number of the problems are flawed, or even completely wrong. The paper therefore includes an evaluation of the problems in the style of a referee report.

Secretary Problems: Weights and Discounts

OpenAIRE

Babaioff, M.; Dinitz, M.; Gupta, A.; Immorlica, Nicole Simone; Talwar, K.

2009-01-01

textabstractThe classical secretary problem studies the problem of selecting online an element (a “secretary”) with maximum value in a randomly ordered sequence. The difficulty lies in the fact that an element must be either selected or discarded upon its arrival, and this decision is irrevocable. Constant-competitive algorithms are known for the classical secretary problems and several variants. We study the following two extensions of the secretary problem: In the discounted secretary probl...

Solar neutrino problem

Energy Technology Data Exchange (ETDEWEB)

Faulkner, D J [Australian National Univ., Canberra. Mount Stromlo and Siding Spring Observatories

1975-10-01

This paper reviews several recent attempts to solve the problem in terms of modified solar interior models. Some of these have removed the count rate discrepancy, but have violated other observational data for the sun. One successfully accounts for the Davis results at the expense of introducing an ad hoc correction with no current physical explanation. An introductory description of the problem is given.

Schiffer's Conjecture, Interior Transmission Eigenvalues and Invisibility Cloaking: Singular Problem vs. Nonsingular Problem

OpenAIRE

Liu, Hongyu

2012-01-01

In this note, we present some interesting observations on the Schiffer's conjecture, interior transmission eigenvalue problem and their connections to singular and nonsingular invisibility cloaking problems of acoustic waves.

Problems on Divisibility of Binomial Coefficients

Science.gov (United States)

Osler, Thomas J.; Smoak, James

2004-01-01

Twelve unusual problems involving divisibility of the binomial coefficients are represented in this article. The problems are listed in "The Problems" section. All twelve problems have short solutions which are listed in "The Solutions" section. These problems could be assigned to students in any course in which the binomial theorem and Pascal's…

Challenging problems in algebra

CERN Document Server

Posamentier, Alfred S

1996-01-01

Over 300 unusual problems, ranging from easy to difficult, involving equations and inequalities, Diophantine equations, number theory, quadratic equations, logarithms, more. Detailed solutions, as well as brief answers, for all problems are provided.

Estimation of organ cumulated activities and absorbed doses on intakes of several 11C labelled radiopharmaceuticals from external measurement with thermoluminescent dosimeters.

Science.gov (United States)

Nakamura, T; Hayashi, Y; Watabe, H; Matsumoto, M; Horikawa, T; Fujiwara, T; Ito, M; Yanai, K

1998-02-01

We have developed a method for obtaining the cumulated activities in organs from radionuclides, which are injected into the patient in nuclear medicine procedures, by external exposure measurement with thermoluminescent dosimeters (TLDs) which are attached to the patient's body surface close to source organs to obtain information on body-surface doses. As the surface dose is connected to the cumulated activities in source organs through radiation transmission in the human body which can be estimated with the aid of a mathematical phantom, the organ cumulated activities can be obtained by the inverse transform method. The accuracy of this method was investigated by using a water phantom in which several gamma-ray volume sources of known activity were placed to simulate source organs. We then estimated by external measurements the organ cumulated activities and absorbed doses in subjects to whom the radiopharmaceuticals 11C-labelled Doxepin, 11C-labelled YM09151-2 and 11C-labelled Benzotropin were administered in clinical nuclear medicine procedures. The cumulated activities in the brain obtained with TLDs for Doxepin and YM09151-2 are 63.6 +/- 6.2 and 32.1 +/- 12.0 kBq h MBq-1 respectively, which are compared with the respective values of 33.3 +/- 9.9 and 23.9 +/- 6.2 kBq h MBq-1 with direct PET (positron emission tomography) measurements. The agreement between the two methods is within a factor of two. The effective doses of Doxepin, YM09151-2 and Benzotropin are determined as 6.92 x 10(-3), 7.08 x 10(-3) and 7.65 x 10(-3) mSv MBq-1 respectively with the TLD method. This method has great advantages, in that cumulated activities in several organs can be obtained easily with a single procedure, and the measurements of body surface doses are performed simultaneously with the nuclear medicine procedure, as TLDs are too small to interfere with other medical measurements.

Estimation of organ cumulated activities and absorbed doses on intakes of several {sup 11}C labelled radiopharmaceuticals from external measurement with thermoluminescent dosimeters

Energy Technology Data Exchange (ETDEWEB)

Nakamura, Takashi; Hayashi, Yoshiharu; Watabe, Hiroshi; Matsumoto, Masaki; Horikawa, Tohru; Fujiwara, Takehiko; Ito, Masatoshi; Yanai, Kazuhiko [Cyclotron and Radioisotope Center, Tohoku University, Aoba, Aramaki, Sendai 980-77 (Japan)

1998-02-01

We have developed a method for obtaining the cumulated activities in organs from radionuclides, which are injected into the patient in nuclear medicine procedures, by external exposure measurement with thermoluminescent dosimeters (TLDs) which are attached to the patient's body surface close to source organs to obtain information on body-surface doses. As the surface dose is connected to the cumulated activities in source organs through radiation transmission in the human body which can be estimated with the aid of a mathematical phantom, the organ cumulated activities can be obtained by the inverse transform method. The accuracy of this method was investigated by using a water phantom in which several gamma-ray volume sources of known activity were placed to simulate source organs. We then estimated by external measurements the organ cumulated activities and absorbed doses in subjects to whom the radiopharmaceuticals {sup 11}C-labelled Doxepin, {sup 11}C-labelled YM09151-2 and {sup 11}C-labelled Benzotropin were administered in clinical nuclear medicine procedures. The cumulated activities in the brain obtained with TLDs for Doxepin and YM09151-2 are 63.6{+-}6.2 and 32.1{+-}12.0 kBq h MBq{sup -1} respectively, which are compared with the respective values of 33.3{+-}9.9 and 23.9{+-}6.2 kBq h MBq{sup -1} with direct PET (positron emission tomography) measurements. The agreement between the two methods is within a factor of two. The effective doses of Doxepin, YM09151-2 and Benzotropin are determined as 6.92x10{sup -3}, 7.08x10{sup -3} and 7.65x10{sup -3} mSv MBq{sup -1} respectively with the TLD method. This method has great advantages, in that cumulated activities in several organs can be obtained easily with a single procedure, and the measurements of body surface doses are performed simultaneously with the nuclear medicine procedure, as TLDs are too small to interfere with other medical measurements. (author)