Maximal subgroups of finite groups
S. Srinivasan
1990-01-01
Full Text Available In finite groups maximal subgroups play a very important role. Results in the literature show that if the maximal subgroup has a very small index in the whole group then it influences the structure of the group itself. In this paper we study the case when the index of the maximal subgroups of the groups have a special type of relation with the Fitting subgroup of the group.
In 2013, an epidemic of lettuce yellows occurred in the Winter Garden region of Texas. The infected plants were stunted with blanching and chlorosis in young heart leaves. A total of thirteen samples, including three apparently asymptomatic, from Romaine and leaf lettuce cultivars, on two different...
Finite groups all of whose minimal subgroups are *-subgroups
Yonggang Li; Xianggui Zhong
2014-11-01
Let be a finite group. A subgroup of is called an -subgroup of if it satisfies $H^G \\cap N_{G}(H) = H$. A subgroup of is said to be a *-subgroup of if there exists a subnormal subgroup of such that = and $H \\cap T$ is a -subgroup of . In this article, we investigate the structure of under the assumption that subgroups of prime order are *-subgroups of . The finite groups, all of whose minimal subgroups of the generalized Fitting subgroup are *-subgroups are classified.
Congruence Subgroups of Hecke Groups
Bo CHEN; Ping Zhi YUAN
2009-01-01
Hecke groups are an important tool in investigating functional equations, and congruence subgroups of Hecke groups play an important rule in research of the solutions of the Dirichlet series.When q, m are two primes, congruence subgroups and the principal congruence subgroups of level m of the Hecke group H(√q) have been investigated in many papers. In this paper, we generalize these results to the case where q is a positive integer with q ≥ 5, √q ￠ Z and m is a power of an odd prime.
FINITE GROUPS WHOSE MINIMAL SUBGROUPS ARE WEAKLY H-SUBGROUPS
M.M.Al-Mosa Al-Shomrani; M.Ramadan; A.A.Heliel
2012-01-01
Let G be a finite group.A subgroup H of G is called an H-subgroup in G if NG(H) ∩H9 ≤ H for all g ∈ G.A subgroup H of G is called a weakly H-subgroup in G if there exists a normal subgroup K of G such that G =HK and H ∩ K is an H-subgroup in G.In this paper,we investigate the structure of the finite group G under the assumption that every subgroup of G of prime order or of order 4 is a weakly H-subgroup in G.Our results improve and generalize several recent results in the literature.
Finite Groups with Some -Supplemented Subgroups
Guo Zhong
2013-01-01
Full Text Available Let be a subgroup of a finite group , a prime dividing the order of , and a Sylow -subgroup of for prime We say that is -supplemented in if there is a subgroup of such that and where denotes the subgroup of generated by all those subgroups of which are -quasinormally embedded in In this paper, we characterize -nilpotency and supersolvability of under the assumption that all maximal subgroups of are -supplemented in .
Tseng, Y.‐W; Deng, W.‐L; Chang, C.‐J; Shih, H.‐T; Su, C.‐C; Jan, F.‐J
2016-01-01
.... Diseased plants exhibited leaf yellowing and witches'‐broom symptoms. Molecular diagnostic tools and electron microscopic cell observation were used to investigate the possible cause of the disease with a specific focus on phytoplasmas...
ON COMPLEMENTED SUBGROUPS OF FINITE GROUPS
无
2001-01-01
A subgroup H of a finite group G is said to be complemented in G if there exists a subgroup K of G such that G = HK and H ∩ K ＝ 1. In this case, K is called a complement of H in G.In this note some results on complemented subgroups of finite groups are obtained.
Maximal Subgroups of Skew Linear Groups
M. Mahdavi-Hezavehi
2002-01-01
Let D be an infinite division algebra of finite dimension over its centre Z(D) = F, and n a positive integer. The structure of maximal subgroups of skew linear groups are investigated. In particular, assume N is a normal subgroup of GLn(D) and M is a maximal subgroup of N containing Z(N). It is shown that if M/Z(N) is finite, then N is central.
Representations of Subgroups of Universal Triangle Groups
Jianguo Xia
2007-01-01
Let G be a universal triangle group, and H a subgroup of G such that the chamber system △H is a tight triangle geometryThen H, which is canonically isomorphic to the topological fundamental group π1(△H) of △ H, is a finitely presented group.For some H we give their representations.
Finite groups in which some particular subgroups are TI-subgroups
Shi, Jiangtao; Zhang, Cui
2013-01-01
We prove that G is a group in which all noncyclic subgroups are TI-subgroups if and only if all noncyclic subgroups of G are normal in G. Moreover, we classify groups in which all subgroups of even order are TI-subgroups....
Finite Groups with Seminormal Sylow Subgroups
Wen Bin GUO
2008-01-01
In this paper,we prove the following theorem:Let p be a prime number,P a Sylow psubgroup of a group G and π = π(G) \\ {p}.If P is seminormal in G,then the following statements hold:1) G is a p-soluble group and P' ≤Op(G); 2) lp(G) ≤ 2 and lπ(G) < 2; 3) if a π-Hall subgroup of G is q-supersoluble for some q ∈π,then G is q-supersoluble.
A Note on TI-Subgroups of Finite Groups
Jiakuan Lu; Linna Pang
2012-02-01
A subgroup of a finite group is called a TI-subgroup if $H\\cap H^x=1$ or for any $x\\in G$. In this short note, the finite groups all of whose nonabelian subgroups are TI-subgroups are classified.
On c*-Normal Subgroups in Finite Groups
Hua Quan WEI; Wei Ping GU; Hong Fei PAN
2012-01-01
A subgroup H of a finitegroup G is called a c*-normal subgroup of G if there exists a normal subgroup K of G such that G =HK and H ∩ K is an S-quasinormal embedded subgroup of G.In this paper,the structure of a finite group G with some c*-normal maximal subgroups of Sylow subgroups is characterized and some known related results are generalized.
Zhengxing LI; Jinke HAI
2013-01-01
Recall that a subgroup H of a finite group G is called a TI-subgroup if H ∩ Hg =1or H for each g ∈ G.Suppose that G is a finite group whose second maximal subgroups are TI-subgroups.It is shown that every class-preserving Coleman automorphism of G is an inner automorphism.As an immediate consequence of this result,we obtain that the normalizer property holds for G.
Finite Groups with c-Supplemented Minimal Subgroups
Yanming Wang; Yangming Li; Jingtong Wang
2003-01-01
A subgroup H is said to be c-supplemented in a finite group G if there exists a subgroup K of G such that HK = G and H∩K is contained in CoreG(H).We determine the structure of finite groups G with the minimal subgroup of the generalized Fitting subgroup of some normal subgroup of G c-supplemented in G.We also generalize some known results.
Groups Satisfying the Maximal Condition on Non-modular Subgroups
Maria De Falco; Carmela Musella
2005-01-01
In this paper, (generalized) soluble groups for which the set of non-modular subgroups verifies the maximal condition and groups for which the set of non-permutable subgroups satisfies the same property are classified.
Constructing arithmetic subgroups of unipotent groups
de Graaf, Willem; Pavan, Andrea
2008-01-01
Let G be a unipotent algebraic subgroup of some GL_m(C) defined over Q. We describe an algorithm for finding a finite set of generators of the subgroup G(Z) = G \\cap GL_m(Z). This is based on a new proof of the result (in more general form due to Borel and Harish-Chandra) that such a finite generating set exists.
On -Semipermutable Subgroups of Finite Groups and -Nilpotency
Han Zhangjia
2010-04-01
A subgroup of a group is said to be -semipermutable in if it is permutable with every Sylow -subgroup of with $(p,|H|)=1$. Using the concept of -semipermutable subgroups, some new characterizations of -nilpotent groups are obtained and several results are generalized.
On Certain Distributive Lattices of Subgroups of Finite Soluble Groups
L.M.EZQUERRO; X. SOLER-ESCRIV(A)
2007-01-01
In this paper, we prove the following result. Let (S) be a saturated formation and ∑ a Hall system of a soluble group G. Let X be a w-solid set of maximal subgroups of G such that ∑ reduces into each element of X. Consider in G the following three subgroups: the (S)-normalizer D of G associated with ∑; the X-prefrattini subgroup W = W(G, X) of G; and a hypercentrally embedded subgroup T of G. Then the lattice (ε)(T, W, D) generated by T, D and W is a distributive lattice of pairwise permutable subgroups of G with the cover and avoidance property.This result remains true for the lattice (ε)(V, W, D), where V is a subgroup of G whose Sylow subgroups are also Sylow subgroups of hypercentrally embedded subgroups of G such that ∑ reduces into V.
$\\mathcal M^\\ast$-supplemented subgroups of finite groups
Jia Zhang; Long Miao; Juping Tang
2016-05-01
A subgroup $H$ of a group $G$ is said to be $\\mathcal M^\\ast$-supplemented in $G$ if there exists a subgroup $K$ of $G$ such that $G = HK$ and $H \\cap K$ is $\\mathcal M$-supplemented in $G$. In this paper, we prove as follows: Let $E$ be a normal subgroup of a group $G$. Suppose that every maximal subgroup of every non-cyclic Sylow subgroup $P$ of $F^\\ast (E)$ is $\\mathcal M^\\ast$-supplemented in $G$, then $E \\leq Z_{\\mathcal U\\Phi} (G)$.
Subgroup s-commutativity degree of finite groups
Otera, Daniele Ettore
2010-01-01
In a recent contribution, Tarnauceanu has introduced the subgroup commutativity degree of a finite group, adapting to the context of the lattice theory some ideas and some techniques, which were known by the studies of Lescot on the commutativity degree. This new notion allows us to detect how a group is far from having all subgroups which are permutable. In the present paper we investigate a probability, which generalizes the subgroup commutativity degree, and find some numerical restrictions on groups which are rich in S-permutable subgroups in the sense of Kegel.
BAYESIAN NETWORKS FOR SUB-GROUPS OF MULTIPLE SCLEROSIS
2013-01-01
In this study, patients with multiple sclerosis "sub-groups" characteristics in relation to detection of a statistically (SPSS) and are provided in the Bayesian network. The main objective of this study, regarding the appearance of MRI lesions in patients with Multiple Sclerosis information and / or EDSS scores to investigate the possible attack of multiple sclerosis subgroups. Bayesian networks, reflects the level of sub-groups in multiple sclerosis patients. Analyzes were conducted...
On discrete Zariski-dense subgroups of algebraic groups
Winkelmann, J
1993-01-01
We investigate for which linear-algebraic groups (over the complex numbers or any local field) there exists subgroups which are dense in the Zariski topology, but discrete in the Hausdorff topology. For instance, such subgroups exist for every non-solvable complex group.
Finite Groups with Given Quantitative Non-Nilpotent Subgroups II
Shi, Jiangtao; Zhang, Cui
2014-01-01
As an extension of Shi and Zhang's 2011 article [4], we prove that any finite group having at most 23 non-normal non-nilpotent proper subgroups is solvable except for G ≅ A 5 or SL(2, 5), and any finite group having at most three conjugacy classes of non-normal non-nilpotent proper subgroups is s...
On p-nilpotency and minimal subgroups of finite groups
GUO; Xiuyun(郭秀云); K.P.Shum
2003-01-01
We call a subgroup H of a finite group G c-supplemented in G if there exists a subgroup K ofG such that G = HK and H ∩K ≤ core(H). In this paper it is proved that a finite group G is p-nilpotentif G is S4-free and every minimal subgroup of P ∩ GN is c-supplemented in NG(P), and when p = 2 P isquaternion-free, where p is the smallest prime number dividing the order of G, P a Sylow p-subgroup of G.As some applications of this result, some known results are generalized.
The Demazure-Tits subgroup of a simple Lie group
Michel, L.; Patera, J.; Sharp, R. T.
1988-04-01
The Demazure-Tits subgroup of a simple Lie group G is the group of invariance of Clebsch-Gordan coefficients tables (assuming an appropriate choice of basis). The structure of the Demazure-Tits subgroups of An, Bn, Cn, Dn, and G2 is described. Orbits of the permutation action of the DT group in any irreducible finite-dimensional representation space of A2, C2, and G2 are decomposed into the sum of irreducible representations of the DT group.
On Maximal Subgroups of a Finite Solvable Group
Gritsuk, D V
2011-01-01
The following result is received: Let $H$ be a non-normal maximal subgroup of a finite solvable group $G$ and let $q \\in \\pi(F(H/\\mathrm{Core}_GH))$, then $G$ has a Sylow $q$-subgroup $Q$ such that $N_{G}(Q) \\subseteq H$.
On Approximation of Lie Groups by Discrete Subgroups
Hatem Hamrouni; Salah Souissi
2014-02-01
A locally compact group is said to be approximated by discrete sub-groups (in the sense of Tôyama) if there is a sequence of discrete subgroups of that converges to in the Chabauty topology (or equivalently, in the Vietoris topology). The notion of approximation of Lie groups by discrete subgroups was introduced by Tôyama in Kodai Math. Sem. Rep. 1 (1949) 36–37 and investigated in detail by Kuranishi in Nagoya Math. J. 2 (1951) 63–71. It is known as a theorem of Tôyama that any connected Lie group approximated by discrete subgroups is nilpotent. The converse, in general, does not hold. For example, a connected simply connected nilpotent Lie group is approximated by discrete subgroups if and only if has a rational structure. On the other hand, if is a discrete uniform subgroup of a connected, simply connected nilpotent Lie group then is approximated by discrete subgroups $_n$ containing . The proof of the above result is by induction on the dimension of , and gives an algorithm for inductively determining $_n$. The purpose of this paper is to give another proof in which we present an explicit formula for the sequence $(_n)_{n≥ 0}$ in terms of . Several applications are given.
On subgroups of saturated or totally bounded paratopological groups
Banakh, Taras
2010-01-01
A paratopological group $G$ is saturated if the inverse $U^{-1}$ of each non-empty set $U\\subset G$ has non-empty interior. It is shown that a [first-countable] paratopological group $H$ is a closed subgroup of a saturated (totally bounded) [abelian] paratopological group if and only if $H$ admits a continuous bijective homomorphism onto a (totally bounded) [abelian] topological group $G$ [such that for each neighborhood $U\\subset H$ of the unit $e$ there is a closed subset $F\\subset G$ with $e\\in h^{-1}(F)\\subset U$]. As an application we construct a paratopological group whose character exceeds its $\\pi$-weight as well as the character of its group reflexion. Also we present several examples of (para)topological groups which are subgroups of totally bounded paratopological groups but fail to be subgroups of regular totally bounded paratopological groups.
On uc-Normal Subgroups of Finite Groups
A.Y. Alsheik Ahmad; J.J. Jaraden; Alexander N. Skiba
2007-01-01
Let G be a finite group. We say that a subgroup H of G is Uc-normal in G if G has a subnormal subgroup T such that TH ＝ G and (H ∩ T)HG/HG is contained in the U-hypercenter Zu∞ (G/HG) of G/HG, where U is the class of the finite supersoluble groups. We study the structure of G under the assumption that some subgroups of G are Uc-normal in G.
BAYESIAN NETWORKS FOR SUB-GROUPS OF MULTIPLE SCLEROSIS
Yeliz KARACA
2013-01-01
Full Text Available In this study, patients with multiple sclerosis "sub-groups" characteristics in relation to detection of a statistically (SPSS and are provided in the Bayesian network. The main objective of this study, regarding the appearance of MRI lesions in patients with Multiple Sclerosis information and / or EDSS scores to investigate the possible attack of multiple sclerosis subgroups. Bayesian networks, reflects the level of sub-groups in multiple sclerosis patients. Analyzes were conducted to determine the change of these properties. MR images of the input data is discussed for the MS patients, the sub-groups of MS, "Remitting Relapsing Multiple Sclerosis", "Secondary Progressive Multiple Sclerosis" with their patients' clinical brain MR images, brain stem, and the Upper Cervical Regions of the corpus callosum-periventricular lesions created in the information. Multiple Sclerosis is owned by the input data is created correctly identify disease subgroups of MS patients for the number of lesions in MR images and MR image of the three regions for the year for which the information used in the EDSS score. Of MS is RRMS, SPMS correctly identify sub-groups of the brain with Brain Stem, and upper cervical regions of the corpus callosum-periventricular lesions in these three points for the region and / or EDSS score information can be emphasized by using the Bayesian networks play an important role in the analysis.
A conjugacy criterion for Hall subgroups in finite groups
Revin, D O
2010-01-01
A finite group $G$ is said to satisfy $C_\\pi$ for a set of primes $\\pi$, if $G$ possesses exactly one class of conjugate $\\pi$-Hall subgroups. In the paper we obtain a criterion for a finite group $G$ to satisfy $C_\\pi$ in terms of a normal series of the group.
Carter subgroups of singular classical groups over finite fields
高有; 石新华
2004-01-01
Let Fq be a finite field with qelements whereq = pα. In the present paper, the authors study the existence and structure of Carter subgroups of singular symplectic group Sp (Fq), singular unitary group U ( Fq2 ) and singular orthogonal group O ( Fq ) ( n is even) over finite fields Fq.
Some remarks on regular subgroups of the affine group
M. Chiara Tamburini Bellani
2012-03-01
Full Text Available Let $V$ be a vector space over a field $F$ of characteristic $pgeq 0$ and let $T$ be a regular subgroup of the affine group $AGL(V$. In the finite dimensional case we show that, if $T$ is abelian or $p>0$, then $T$ is unipotent. For $T$ abelian, pushing forward some ideas used in [A. Caranti, F. Dalla Volta and M. Sala, Abelian regular subgroups of the affine group and radical rings, Publ. Math. Debrecen {bf 69} (2006, 297--308.], we show that the set $left{t-Imid tin Tright}$ is a subalgebra of $End_F(Foplus V$, which is nilpotent when $V$ has finite dimension. This allows a rather systematic construction of abelian regular subgroups.
On Isomorphism Testing of Groups with Normal Hall Subgroups
You-Ming Qiao; Jayalal Sarma M.N.; Bang-Sheng Tang
2012-01-01
A normal Hall subgroup N of a group G is a normal subgroup with its order coprime with its index.Schur-Zassenhaus theorem states that every normal Hall subgroup has a complement subgroup,that is a set of coset representatives H which also forms a subgroup of G.In this paper,we present a framework to test isomorphism of groups with at least one normal Hall subgroup,when groups are given as multiplication tables.To establish the framework,we first observe that a proof of Schur-Zassenhaus theorem is constructive,and formulate a necessary and sufficient condition for testing isomorphism in terms of the associated actions of the semidirect products,and isomorphisms of the normal parts and complement parts.We then focus on the case when the normal subgroup is abelian.Utilizing basic facts of representation theory of finite groups and a technique by Le Gall (STACS 2009),we first get an efficient isomorphism testing algorithm when the complement has bounded number of generators.For the case when the complement subgroup is elementary abelian,which does not necessarily have bounded number of generators,we obtain a polynomial time isomorphism testing algorithm by reducing to generalized code isomorphism problem,which asks whether two linear subspaces are the same up to permutation of coordinates.A solution to the latter can be obtained by a mild extension of the singly exponential (in the number of coordinates) time algorithm for code isomorphism problem developed recently by Babai et al.(SODA 2011).Enroute to obtaining the above reduction,we study the following computational problem in representation theory of finite groups:given two representations ρ and τ of a group H over Zpd,p a prime,determine if there exists an automorphism φ:H → H,such that the induced representation ρφ =ρоφ and τ are equivalent,in time poly(ㄧHㄧ,pd).
Characteristic Properties of Large Subgroups in Primary Abelian Groups
Peter V Danchev
2004-08-01
Suppose is an arbitrary additively written primary abelian group with a fixed large subgroup . It is shown that is (a) summable; (b)$\\sum$-summable; (c) a $\\sum$-group; (d) $p^{+1}$-projective only when so is . These claims extend results of such a kind obtained by Benabdallah, Eisenstadt, Irwin and Poluianov, Acta Math. Acad. Sci. Hungaricae (1970) and Khan, Proc. Indian Acad. Sci. Sect. A (1978).
Locally Transitive Graphs Admitting a Group with Cyclic Sylow Subgroups*
CHEN SHANG-DI; FENG QING-LIN
2010-01-01
All graphs are finite simple undirected and of no isolated vertices in this paper. Using the theory of coset graphs and permutation groups, it is completed that a classification of locally transitive graphs admitting a non-Abelian group with cyclic Sylow subgroups. They are either the union of the family of arc-transitive graphs, or the union of the family of bipartite edge-transitive graphs.
Combined group ECC protection and subgroup parity protection
Gara, Alan; Cheng, Dong; Heidelberger, Philip; Ohmacht, Martin
2016-02-02
A method and system are disclosed for providing combined error code protection and subgroup parity protection for a given group of n bits. The method comprises the steps of identifying a number, m, of redundant bits for said error protection; and constructing a matrix P, wherein multiplying said given group of n bits with P produces m redundant error correction code (ECC) protection bits, and two columns of P provide parity protection for subgroups of said given group of n bits. In the preferred embodiment of the invention, the matrix P is constructed by generating permutations of m bit wide vectors with three or more, but an odd number of, elements with value one and the other elements with value zero; and assigning said vectors to rows of the matrix P.
Combined group ECC protection and subgroup parity protection
Gara, Alan G.; Chen, Dong; Heidelberger, Philip; Ohmacht, Martin
2013-06-18
A method and system are disclosed for providing combined error code protection and subgroup parity protection for a given group of n bits. The method comprises the steps of identifying a number, m, of redundant bits for said error protection; and constructing a matrix P, wherein multiplying said given group of n bits with P produces m redundant error correction code (ECC) protection bits, and two columns of P provide parity protection for subgroups of said given group of n bits. In the preferred embodiment of the invention, the matrix P is constructed by generating permutations of m bit wide vectors with three or more, but an odd number of, elements with value one and the other elements with value zero; and assigning said vectors to rows of the matrix P.
Dehn twists and free subgroups of symplectic mapping class groups
Keating, Ailsa
2012-01-01
Given two Lagrangian spheres in an exact symplectic manifold, we find conditions under which the Dehn twists about them generate a free non-abelian subgroup of the symplectic mapping class group. This extends a result of Ishida for Riemann surfaces. The proof generalises the categorical version of Seidel's long exact sequence to arbitrary powers of a fixed Dehn twist. We also show that the Milnor fibre of any isolated degenerate hypersurface singularity contains such pairs of spheres.
Ideal Class Groups and Subgroups of Real Quadratic Function Fields
无
2000-01-01
In this paper, we study the real quadratic function fields K=k(D), given a necessary and sufficient condition for the ideal class group H(K) of any real quadratic function field K to have a cyclic subgroup of order n, and obtained eight series of such fields. The ideal class numbers h(OK) of K in the series all have a factor n.
The Influence of Primitive Subgroups on the Structure of Finite Groups
Liu Yu-feng; Du Xian-kun(Communicated)
2013-01-01
A subgroup H of a group G is said to be primitive if it is a proper subgroup of the intersection of all subgroups of G containing H as its proper subgroup. The purpose of this note is to go further into the influence of primitive subgroups on the structure of finite groups. Some new results are obtained.
Symmetry breaking, subgroup embeddings and the Weyl group
George, Damien P; Thompson, Jayne E; Volkas, Raymond R
2013-01-01
We present a systematic approach to writing adjoint Higgs vacuum expectation values (vevs), which break a symmetry G to differently embedded isomorphic copies of a subgroup belonging to the chain $G \\supset H_1 \\supset ... \\supset H_l $, as linear combinations of each other. Given an adjoint Higgs vacuum expectation value h breaking G \\rightarrow H, a full complement of vevs breaking G to different embeddings of the subgroup H can be generated through the Weyl group orbit of h. An explicit formula for recovering each vev is given. We focus on the case when H stabilizes the highest weight of the lowest dimensional fundamental representation, where the formula is exceedingly simple. We also discuss cases when the Higgs field is not in the adjoint representation and apply these techniques to current research problems, especially in domain-wall brane model building.
On the relations between subgroups of a group and submodules of modules over group rings
Alkan, Mustafa
2017-07-01
Let R be a commutative ring and G a finite group. In [1], using a structure on an R-module M to make it an RG-module, we find some relations between RG-submodules and a subgroups. We also prove that for each normal subgroup H of G with an invertible |H| in R, there is a direct summand RG-submodule of M.
As more phytoplasmas are discovered in emerging and re-emerging plant diseases worldwide, the scheme for classification of phytoplasmas into 16S rRNA gene RFLP (16Sr) groups and subgroups is experiencing an ongoing rapid expansion. Improper delineation or designation of new groups and subgroups can...
Representing and Counting the Subgroups of the Group Zm×Zn
Mario Hampejs
2014-01-01
Full Text Available We deduce a simple representation and the invariant factor decompositions of the subgroups of the group Zm×Zn, where m and n are arbitrary positive integers. We obtain formulas for the total number of subgroups and the number of subgroups of a given order.
Gantt, Susan P; Agazarian, Yvonne M
2010-10-01
This article introduces the systems-centered concept of the "group mind" by linking systems-centered thinking and interpersonal neurobiology, building on Siegel's definition of mind as the process of regulating the flow of energy and information. Functional subgrouping, the systems-centered group method for resolving conflicts, discriminates and integrates the flow of energy and information within and between group members, subgroups, and the group-as-a-whole, thus potentiating survival, development, and transformation. This article uses the interpersonal neurobiological framework to discuss functional subgrouping as a tool for developing the group mind: considering how functional subgrouping facilitates emotional regulation, creates a secure relational context, and potentiates neural integration.
LI Zheng-nan; ZHANG Lei; TAO Ye; CHI Ming; XIANG Yu; WU Yun-feng
2014-01-01
A novel phytoplasma was detected in a cherry plum (Prunus cerasifera Ehrh) tree that mainly showed yellow leaf symptom. The tree was growing in an orchard located in Yangling District, Shaanxi Province, China. The leaves started as chlorotic and yellowing along leaf minor veins and leaf tips. Chlorosis rapidly developed to inter-veinal areas with the whole leaf becoming pale yellow in about 1-4 wk. Large numbers of phytoplasma-like bodies (PLBs) were seen under transmission electron microscopy. The majority of the PLBs was spherical or elliptical vesicles, with diameters in range of 0.1-0.6 µm, and distributed in the phloem cells of the infected tissues. A 1 246-bp 16S ribosomal RNA (rRNA) gene fragment was ampliifed from DNA samples extracted from the yellow leaf tissues using two phytoplasma universal primer pairs R16mF2/R16mR1 and R16F2n/R16R2. Phylogenetic analysis using the 16S rRNA gene sequence suggested that the phytoplasma associated with the yellow leaf symptoms belongs to a novel subclade in the aster yellows (AY) group (16SrI group). Virtual and actual restriction fragment length polymorphism (RFLP) analysis of the 16S rRNA gene fragment revealed that the phytoplasma was distinguishable from all existing 19 subgroups in the AY group (16SrI) by four restriction sites, Hinf I, Mse I, Sau3A I and Taq I. The similarity coefifcients of comparing the RFLP pattern of the 16S rRNA gene fragment of this phytoplasma to each of the 19 reported subgroups ranged from 0.73 to 0.87, which indicates the phytoplasma associated with the cherry plum yellow leaf (CPYL) symptoms is probably a distinct and novel subgroup lineage in the AY group (16SrI). In addition, the novel phytoplasma was experimentally transmitted to periwinkle (Catharanthus roseus) plants from the tree with CPYL symptoms and then back to a healthy 1-yr-old cherry plum tree via dodder (Cuscuta odorata) connections.
Amira Ghorbel
2009-02-01
Full Text Available The discrete cocompact subgroups of the five-dimensional connected, simply connected nilpotent Lie groups are determined up to isomorphism. Moreover, we prove if G = N × A is a connected, simply connected, nilpotent Lie group with an Abelian factor A, then every uniform subgroup of G is the direct product of a uniform subgroup of N and Z^r where r = dim A.
On p-Nilpotency of Finite Groups with Some Subgroups c-Supplemented
Xiuyun Guo; K.P. Shum
2003-01-01
A subgroup H of a group G is said to be c-supplemented in G if there exists a subgroup K of G such that G = HK and H∩K is contained in coreG(H).In this paper we prove that a group G is p-nilpotent if every maximal subgroup of P is c-supplemented in G and (|G|, p - 1) = 1, where p is a prime factor of the order of G and P is a Sylow p-subgroup of We also give a condition for a group to be p-nilpotent by using the 2-maximal subgroups of the Sylow p-subgroups.
On the number of classes of conjugate Hall subgroups in finite simple groups
Revin, D O
2009-01-01
In this paper we find the number of conjugate $\\pi$-Hall subgroups in all finite almost simple groups. We also complete the classification of $\\pi$-Hall subgroups in finite simple groups and correct some mistakes from our previous paper.
Groups in Which 2-Generator Subgroups Are Nilpotent of Bounded Class
Costantino Delizia
2001-01-01
In this paper, we study some properties of groups in which subgroups with a fixed number of generators are nilpotent. In particular, we discuss nilpotency of torsion-free groups in which 2-generator subgroups are nilpotent of class at most 4.
Finite p-groups all of whose maximal abelian subgroups are soft
无
2010-01-01
A subgroup A of a p-group G is said to be soft in G if CG(A) = A and |NG(A)/A| = p. In this paper we determined finite p-groups all of whose maximal abelian subgroups are soft; see Theorem A and Proposition 2.4.
Subgroups of ideal class groups of real quadratic algebraic function fields
WANG; Kunpeng(王鲲鹏); ZHANG; Xianke(张贤科)
2003-01-01
Necessary and sufficient condition on real quadratic algebraic function fields K is given for theirideal class groups H(K) to contain cyclic subgroups of order n. And eight series of such real quadratic functionfields K are obtained whose ideal class groups contain cyclic subgroups of order n. In particular, the ideal classnumbers of these function fields are divisible by n.
Life of Pizza Pie: The Implications of Sub-Group Comparisons in Education
Thomas, Tara N.
2013-01-01
Current educational statistics have pitted subgroups against one another without consideration of the actual population sizes of each group. This paper is intended to provided a clearer understanding of the current usage of sub-group comparisons in American education. (Contains 4 figures.)
An Investigation on the Parabolic Subgroups of the General Linear Groups by Using GAP
SaadABedaiwi; LIShang-zhi
2004-01-01
A typical example for the algebraic groups is the general linear groups G=GL(n,F), we have studied the structure of such groups and paid special attention to its important substructures, namely the Parabolic subgroups. For a given G we computed all the Parabolic subgroups and determined their number, depending on the fact that any finite group has a composition series and the composition factors of a composition series are simple groups which are completely classified, we report here some investigations on the computed Parabolic subgroups. This has been done with the utility of GAP.
Malnormal subgroups of lattices and the Pukanszky invariant in group factors
Robertson, Guyan
2009-01-01
Let $G$ be a connected semisimple real algebraic group. Assume that $G(\\bb R)$ has no compact factors and let $\\Gamma$ be a torsion-free uniform lattice subgroup of $G(\\bb R)$. Then $\\Gamma$ contains a malnormal abelian subgroup $A$. This implies that the $\\tto$ factor $\\vn(\\Gamma)$ contains a masa $\\fk A$ with Puk\\'anszky invariant $\\{\\infty\\}$.
Nilpotency and Theory of L-Subgroups of an L-Group
Naseem Ajmal
2014-03-01
Full Text Available In this paper, the notion of commutator is modified and extended to L-setting. Also, the notion of descending central series is introduced which is used to formulate the important notion of nilpotent L-subgroup of an L-group. Moreover, the level subset characterization for the notion of nilpotent L-subgroup is provided.
The influence of X-semipermutability of subgroups on the structure of finite groups
无
2009-01-01
Let A be a subgroup of a group G and X be a nonempty subset of G. A is said to be X-semipermutable in G if A has a supplement T in G such that A is X-permutable with every subgroup of T. In this paper, we investigate further the influence of X-semipermutability of some subgroups on the structure of finite groups. Some new criteria for a group G to be supersoluble or p-nilpotent are obtained.
Modules over group rings of groups with restrictions on the system of all proper subgroups
Olga Dashkova
2015-12-01
Full Text Available We consider the class M of R{modules where R is an associative ring. Let A be a module over a group ring RG, G be a group and let L(G be the set of all proper subgroups of G. We suppose that if H 2 L(G then A=CA(H belongs to M. We study an RG{module A such that G 6= G0, CG(A = 1. We consider the cases: 1 M is the class of all artinian R{modules, R is either the ring of integers or the ring of p{adic integers; 2 M is the class of all nite R{modules, R is an associative ring; 3 M is the class of all nite R{modules, R= F is a nite eld.
Normal Subgroup Growth of Linear Groups: the (G2; F4;E8)-Theorem
Larsen, Michael
2011-01-01
Let G be a finitely generated group and M_n(G) the number of its normal subgroup subgroups of index at most n. For linear groups G we show that M_n(G) can grow polynomially in n only if the semisimple part of the Zariski closure of G has simple components only of type G2, F4 or E8 (and in this case indeed this can happened!)
On a finite group having a normal series whose factors have bicyclic Sylow subgroups
Monakhov, V S
2009-01-01
We consider the structure of a finite groups having a normal series whose factors have bicyclic Sylow subgroups. In particular, we investigated groups of odd order and $A_4$-free groups with this property. Exact estimations of the derived length and nilpotent length of such groups are obtained.
Divide and Conquer: Sub-Grouping of ASD Improves ASD Detection Based on Brain Morphometry.
Katuwal, Gajendra J; Baum, Stefi A; Cahill, Nathan D; Michael, Andrew M
2016-01-01
Low success (ASD) classification using brain morphometry from the large multi-site ABIDE dataset and inconsistent findings on brain morphometric abnormalities in ASD can be attributed to the ASD heterogeneity. In this study, we show that ASD brain morphometry is highly heterogeneous, and demonstrate that the heterogeneity can be mitigated and classification improved if autism severity (AS), verbal IQ (VIQ) and age are used with morphometric features. Morphometric features from structural MRIs (sMRIs) of 734 males (ASD: 361, controls: 373) of ABIDE were derived using FreeSurfer. Applying the Random Forest classifier, an AUC of 0.61 was achieved. Adding VIQ and age to morphometric features, AUC improved to 0.68. Sub-grouping the subjects by AS, VIQ and age improved the classification with the highest AUC of 0.8 in the moderate-AS sub-group (AS = 7-8). Matching subjects on age and/or VIQ in each sub-group further improved the classification with the highest AUC of 0.92 in the low AS sub-group (AS = 4-5). AUC decreased with AS and VIQ, and was the lowest in the mid-age sub-group (13-18 years). The important features were mainly from the frontal, temporal, ventricular, right hippocampal and left amygdala regions. However, they highly varied with AS, VIQ and age. The curvature and folding index features from frontal, temporal, lingual and insular regions were dominant in younger subjects suggesting their importance for early detection. When the experiments were repeated using the Gradient Boosting classifier similar results were obtained. Our findings suggest that identifying brain biomarkers in sub-groups of ASD can yield more robust and insightful results than searching across the whole spectrum. Further, it may allow identification of sub-group specific brain biomarkers that are optimized for early detection and monitoring, increasing the utility of sMRI as an important tool for early detection of ASD.
Some Sufficient Conditions on the Number of Non-abelian Subgroups of a Finite Group to be Solvable
Jiang Tao SHI; Cui ZHANG
2011-01-01
Thompson's theorem indicates that a finite group with a nilpotent maximal subgroup of odd order is solvable. As an important application of Thompson's theorem, a finite group is solvable if it has an abelian .maximal subgroup. In this paper, we give some sufficient conditions on the number of non-abelian subgroups of a finite group to be solvable.
Hyperbolically embedded subgroups and rotating families in groups acting on hyperbolic spaces
Dahmani, F; Osin, D
2017-01-01
The authors introduce and study the notions of hyperbolically embedded and very rotating families of subgroups. The former notion can be thought of as a generalization of the peripheral structure of a relatively hyperbolic group, while the latter one provides a natural framework for developing a geometric version of small cancellation theory. Examples of such families naturally occur in groups acting on hyperbolic spaces including hyperbolic and relatively hyperbolic groups, mapping class groups, Out(F_n), and the Cremona group. Other examples can be found among groups acting geometrically on CAT(0) spaces, fundamental groups of graphs of groups, etc. The authors obtain a number of general results about rotating families and hyperbolically embedded subgroups; although their technique applies to a wide class of groups, it is capable of producing new results even for well-studied particular classes. For instance, the authors solve two open problems about mapping class groups, and obtain some results which are n...
Metrization criteria for compact groups in terms of their dense subgroups
Dikranjan, Dikran
2011-01-01
According to Comfort, Raczkowski and Trigos-Arrieta, a dense subgroup D of a compact abelian group G determines G if the restriction homomorphism hat{G}-->hat{D} of the dual groups is a topological isomorphism. We prove (in ZFC) that a compact abelian group determined by all its G_delta-dense subgroups is metrizable, thereby resolving Question 5.12(iii) from [S. Hernandez, S. Macario and F. J. Trigos-Arrieta, Uncountable products of determined groups need not be determined, J. Math. Anal. Appl. 348 (2008), 834--842]. (Under the additional assumption of the Continuum Hypothesis CH, the same statement was proved recently by Bruguera, Chasco, Dominguez, Tkachenko and Trigos-Arrieta.) Under CH, we prove a stronger version of this theorem saying that every compact abelian group determined by all its dense countably compact subgroups is metrizable. For every infinite cardinal kappa, we show that even a dense kappa-bounded minimal (=essential) subgroup of a compact abelian group need not determine it.
The Hidden Subgroup Problem in Affine Groups Basis Selection in Fourier Sampling
Moore, Cristopher; Russell, A; Schulman, L; Moore, Cristopher; Rockmore, Daniel; Russell, Alexander; Schulman, Leonard
2002-01-01
Some quantum algorithms, including Shor's celebrated factoring and discrete log algorithms, proceed by reduction to a hidden subgroup problem, in which a subgroup H of a group G must be determined from a quantum state uniformly supported on a left coset of H. These hidden subgroup problems are then solved by Fourier sampling: the quantum Fourier transform of the state is computed and measured. When the underlying group is non-Abelian, two important variants of the Fourier sampling paradigm have been identified: the weak standard method, where only representation names are measured, and the strong standard method, where full measurement occurs. It has remained open whether the strong standard method is indeed stronger, that is, whether there are hidden subgroups which can be reconstructed via the strong method by not by the weak, or any other known, method. In this article, we settle this question in the affirmative. We show that hidden subgroups of semidirect products of Z/p by Z/q, where q | (p-1) and q >= p...
Strong Sperner property of the subgroup lattice of an Abelian p-group
王军; 王毅
2000-01-01
Let n and k be arbitrary positive integers, p a prime number and L(kn)(p) the subgroup lattice of the Abelian p-group ( /pk )n. Then there is a positive integer N( n, k) such that when p > N( n, k), L(kn)(p) has the strong Sperner property.
Strong Sperner property of the subgroup lattice of an Abelian p-group
无
2000-01-01
Let n and k be arbitrary positive integers, p a prime number and L(kn)(p) the subgroup lattice of the Abelian p-group (Z/pkZ)n. Then there is a positive integer N(n,k) such that when p>N(n,k), L(kn)(p) has the strong Sperner property.
Reflection subgroups and sub-root systems of the imprimitive complex reflection groups
无
2010-01-01
Based on a graph-theoretic analysis,we determine all the irreducible reflection subgroups of the imprimitive complex reflection groups G(m,p,n),and describe the irreducible subsystems of all possible types in the root system R(m,p,n) of G(m,p,n).
Demir, Ergül
2017-01-01
In this study, the aim was to construct a significant structural measurement model comparing students' affective characteristics with their mathematic achievement. According to this model, the aim was to test the measurement invariances between gender sub-groups hierarchically. This study was conducted as basic and descriptive research. Secondary…
TP53 Polymorphisms allow for genetic sub-grouping of the canine transmissible venereal tumor
Sánchez-Servín, Abel; Córdova-Alarcon, Emilio; Fajardo, Raúl
2009-01-01
The canine transmissible venereal tumor (CTVT) is found mainly in dogs' sexual organs. Currently, it is widely accepted that all samples of CTVT show similar histopathological characteristics and share common genetic alterations. Despite the common genetic origin of CTVT, mutations in the P53 gene have been reported. In this study, we proposed that tumor samples can be genetically grouped using this gene. The presence of different subgroups of CTVT was determined in Mexican dogs using the TP53 gene sequence in CTVT samples. Four new polymorphisms were found and therefore, the CTVT samples were classified in five subgroups. PMID:19934603
Subexponential-Time Algorithms for Hidden Subgroup Problems Over Product Groups
Alagic, G; Russell, A; Alagic, Gorjan; Moore, Cristopher; Russell, Alexander
2006-01-01
We study the hidden subgroup problem (HSP) over groups of the form G^n where G is a group of constant size. While these groups are structurally simpler than the symmetric groups S_n, for which solving the HSP would yield a quantum algorithm for Graph Isomorphism, they share an important property with S_n: almost all of their irreducible representations are exponentially large. As a consequence, recent negative results show that any quantum algorithm that attempts to solve the HSP over these groups by measuring coset states must perform highly entangled measurements on \\Omega(n) registers. This distinguishes them from, say, the dihedral groups, whose representations are of constant size and where single-register Fourier sampling provides sufficient information to solve the HSP. Here we give quantum algorithms for many groups of this form, which distinguish an order-2 subgroup from the trivial subgroup in time 2^{O(\\sqrt{n \\log n})}. Our algorithm combines the general idea behind Kuperberg's sieve for dihedral ...
On the Set of the Numbers of Conjugates of Noncyclic Proper Subgroups of Finite Groups
Shi, Jiangtao; Zhang, Cui
2013-01-01
Let G be a finite group and (G) the set of the numbers of conjugates of noncyclic proper subgroups of G. We prove that (1) if |(G)| ≤ 2, then G is solvable, and (2) G is a nonsolvable group with |(G)| = 3 if and only if G≅PSL(2,5) or PSL(2,13) or SL(2,5) or SL(2,13)....
Noether's problem for $p$-groups with an abelian subgroup of index $p$
Michailov, Ivo M
2012-01-01
Let $K$ be a field and $G$ be a finite group. Let $G$ act on the rational function field $K(x(g):g\\in G)$ by $K$ automorphisms defined by $g\\cdot x(h)=x(gh)$ for any $g,h\\in G$. Denote by $K(G)$ the fixed field $K(x(g):g\\in G)^G$. Noether's problem then asks whether $K(G)$ is rational over $K$. In this paper, we give a positive answer to the Noether's problem for all $p$-groups with an abelian subgroup of index $p$ and with a trivial $p$-th lower central subgroup, provided that $K$ contains sufficient roots of unity.
Phenotypic sub-grouping in microtia using a statistical and a clinical approach.
Luquetti, Daniela V; Saltzman, Babette S; Heike, Carrie L; Sie, Kathleen C; Birgfeld, Craig B; Evans, Kelly N; Leroux, Brian G
2015-04-01
The clinical presentation of microtia varies widely from minimal morphological abnormalities to complete absence of the ear. In this study we sought to identify and characterize sub-groups of microtia using a statistical and a clinical approach. Photographs of 86 ears were classified in relation to all the external ear components. We used cluster analysis and rater's clinical opinion to identify groups with similar phenotypes in two separate analyses. We used Cramer's Phi coefficient of association to assess the similarity among the clinician's groupings as well as among the statistical sub-phenotypic groups and each of the clinician's groupings. The cluster analysis initially divided the 86 ears into a more and a less severe group. The less severe group included two sub-groups that included ears classified as normal and a group that had very few anomalous components. The group of 48 more affected ears all had abnormalities of the helix crus; antihelix-stem, -superior crus and -inferior crus; and antitragus. These were further divided into 4 sub-phenotypes. There was a moderate degree of association among the raters' groupings (Cramer's Phi: 0.64 to 0.73). The statistical and clinical groupings had a lower degree of association (Cramer's Phi: 0.49 to 0.58). Using standardized characterization of structural abnormalities of the ear we identified six distinct phenotypic groups; correlations with clinicians' groupings were moderate. These clusters may represent groups of ear malformations associated with the same etiology, similar time of insult or target cell population during embryonic development. The results will help inform investigations on etiology.
Li, Xinjian; Lin, Wencheng; Chang, Shuang; Zhao, Peng; Zhang, Xinheng; Liu, Yang; Chen, Weiguo; Li, Baohong; Shu, Dingming; Zhang, Huanmin; Chen, Feng; Xie, Qingmei
2016-10-01
Avian leukosis virus (ALV) causes high mortality associated with tumor formation and decreased fertility, and results in major economic losses in the poultry industry worldwide. Recently, a putative novel ALV subgroup virus named ALV-K was observed in Chinese local chickens. In this study, a novel ALV strain named GD14LZ was isolated from a Chinese local yellow broiler in 2014. The proviral genome was sequenced and phylogenetically analyzed. The replication ability and pathogenicity of this virus were also evaluated. The complete proviral genome sequence of GD14LZ was 7482 nt in length, with a genetic organization typical of replication-competent type C retroviruses lacking viral oncogenes. Sequence analysis showed that the gag, pol and gp37 genes of GD14LZ have high sequence similarity to those of other ALV strains (A-E subgroups), especially to those of ALV-E. The gp85 gene of the GD14LZ isolate showed a low sequence similarity to those other ALV strains (A-E subgroups) but showed high similarity to strains previously described as ALV-K. Phylogenetic analysis of gp85 also suggested that the GD14LZ isolate was related to ALV-K strains. Further study showed that this isolate replicated more slowly and was less pathogenic than other ALV strains. These results indicate that the GD14LZ isolate belongs to the novel subgroup ALV-K and probably arose by recombination of ALV-K with endogenous viruses with low replication and pathogenicity. This virus might have existed in local Chinese chickens for a long time.
The classification of the virtually cyclic subgroups of the sphere braid groups
Gonçalves, Daciberg Lima
2011-01-01
We study the problem of determining the isomorphism classes of the virtually cyclic subgroups of the n-string braid groups B_n(S^2) of the 2-sphere S^2. If n is odd, or if n is even and sufficiently large, we obtain the complete classification. For small even values of n, the classification is complete up to an explicit finite number of open cases. In order to prove our main theorem, we obtain a number of other results of independent interest, notably the characterisation of the centralisers and normalisers of the finite cyclic and dicyclic subgroups of B_n(S^2), a result concerning conjugate powers of finite order elements, an analysis of the isomorphism classes of the amalgamated products that occur as subgroups of B_n(S^2), as well as an alternative proof of the fact that the universal covering space of the n-th configuration space of S^2 has the homotopy type of S^3 if n is greater than or equal to three.
Neculai Curteanu
2007-07-01
Full Text Available The aim of this paper is to investigate the syntactic / semantic substructures (called subgroups of the Romanian verbal group (VG [12], or verbal complex [25], starting with the achievements in the literature, and melted into the device of direct and inverse functional projection within FX-bar theory [7]. The paper examines several problems and their solutions for the syntactic-semantic theories of VG, as discussed in some fundamental papers, and we offer our explanation on the involved syntactic phenomena, the emphasis falling on the VG substructures (verbal subgroups, VSGs, VSG boundaries and composition within VG, direct and inverse FX-bar projections of VG, VG parsing, lexical semantics and intensional~/ extensional logic representations of the Romanian (verbal or nominal predicate.
Finite groups having at most 27 non-normal proper subgroups of non-prime-power order
Shi, Jiangtao; Zhang, Cui
2014-01-01
We prove that any finite group having at most 27 non-normal proper subgroups of non-prime-power order is solvable except for G≅ A5, the alternating group of degree 5.......We prove that any finite group having at most 27 non-normal proper subgroups of non-prime-power order is solvable except for G≅ A5, the alternating group of degree 5....
Sub-grouping and sub-functionalization of the RIFIN multi-copy protein family
Sonnhammer Erik L
2008-01-01
Full Text Available Abstract Background Parasitic protozoans possess many multicopy gene families which have central roles in parasite survival and virulence. The number and variability of members of these gene families often make it difficult to predict possible functions of the encoded proteins. The families of extra-cellular proteins that are exposed to a host immune response have been driven via immune selection to become antigenically variant, and thereby avoid immune recognition while maintaining protein function to establish a chronic infection. Results We have combined phylogenetic and function shift analyses to study the evolution of the RIFIN proteins, which are antigenically variant and are encoded by the largest multicopy gene family in Plasmodium falciparum. We show that this family can be subdivided into two major groups that we named A- and B-RIFIN proteins. This suggested sub-grouping is supported by a recently published study that showed that, despite the presence of the Plasmodium export (PEXEL motif in all RIFIN variants, proteins from each group have different cellular localizations during the intraerythrocytic life cycle of the parasite. In the present study we show that function shift analysis, a novel technique to predict functional divergence between sub-groups of a protein family, indicates that RIFINs have undergone neo- or sub-functionalization. Conclusion These results question the general trend of clustering large antigenically variant protein groups into homogenous families. Assigning functions to protein families requires their subdivision into meaningful groups such as we have shown for the RIFIN protein family. Using phylogenetic and function shift analysis methods, we identify new directions for the investigation of this broad and complex group of proteins.
Koberda, Thomas
2010-01-01
Consider the mapping class group $\\Mod_{g,n}$ of a surface of finite type and a finite collection $F$ of mapping classes. In this paper we prove that there are positive exponents such that after replacing the elements of $F$ by the corresponding powers, they generate a right-angled Artin group. Under some further suitable hypotheses, these mapping classes are the vertex generators of the underlying graph, or form a right-angled Artin system in the terminology which we shall develop. We prove an analogous result for a finite volume real and complex hyperbolic $n$-manifolds, thus establishing the primary result as a rank one type phenomenon for the mapping class group. We also show the unsolvability of the isomorphism problem for finitely generated subgroups of $\\Mod_{g,n}$, and prove a homological rigidity result for right-angled Artin groups which implies a solution to the isomorphism problem for right-angled Artin groups. We thus solve a generalized isomorphism problem for finitely generated subgroups of $\\M...
On Locally Finite Group with CC-Subgroups%含有CC-子群的局部有限群
薛海波; 吕恒
2012-01-01
In this paper, it is proved that;Let G be a locally finite group with a CC-subgroup. If every proper infinite subgroup has no proper CC-subgroup, then G is an extension of divisible abelian P-subgroup of rank q-1 by cyclic group of order q, where p,q are different prime numbers, moreover, every proper infinite subgroup of G is abelian.%主要证明了:G是局部有限群,若G存在CC-子群,但是其每一个无限真子群都不含有CC-子群,则G是秩为q-1的可除阿贝尔p-群被q阶循环群的扩张,其中p,q是互不相同的素数,且G的每一个无限真子群都是阿贝尔群.
An L-Point Characterization of Normality and Normalizer of an L-Subgroup of an L-Group
Naseem Ajmal
2014-06-01
Full Text Available In this paper, we study the notion of normal L-subgroup of an L-group and provide its characterization by an L-point. We also provide a construction of the normalizer of an L-subgroup of a given L-group by using L-points. Moreover, we also discuss the product, homomorphic images and homomorphic preimages of normalizers.
Conjugacy classes in Sylow p-subgroups of finite Chevalley groups in bad characteristic
Bradley, John D
2012-01-01
Let $U = \\mathbf U(q)$ be a Sylow $p$-subgroup of a finite Chevalley group $G = \\mathbf G(q)$. In [GR}] R\\"ohrle and the second author determined a parameterization of the conjugacy classes of $U$, for $\\mathbf G$ of small rank when $q$ is a power of a good prime for $\\mathbf G$. As a consequence they verified that the number $k(U)$ of conjugacy classes of $U$ is given by a polynomial in $q$ with integer coefficients. In the present paper, we consider the case when $p$ is a bad prime for $\\mathbf G$. We obtain a parameterization of the conjugacy classes of $U$, when $\\mathbf G$ has rank less than or equal to 4, and $\\mathbf G$ is not of type $F_4$. In these cases we deduce that $k(U)$ is given by a polynomial in $q$ with integer coefficients; this polynomial is different from the polynomial for good primes.
Drinfeld Doubles for Finite Subgroups of SU(2 and SU(3 Lie Groups
Robert Coquereaux
2013-05-01
Full Text Available Drinfeld doubles of finite subgroups of SU(2 and SU(3 are investigated in detail. Their modular data – S, T and fusion matrices – are computed explicitly, and illustrated by means of fusion graphs. This allows us to reexamine certain identities on these tensor product or fusion multiplicities under conjugation of representations that had been discussed in our recent paper [J. Phys. A: Math. Theor. 44 (2011, 295208, 26 pages], proved to hold for simple and affine Lie algebras, and found to be generally wrong for finite groups. It is shown here that these identities fail also in general for Drinfeld doubles, indicating that modularity of the fusion category is not the decisive feature. Along the way, we collect many data on these Drinfeld doubles which are interesting for their own sake and maybe also in a relation with the theory of orbifolds in conformal field theory.
张志让; 邓理平; 和佩佩
2013-01-01
Azarian M K将Tang C Y得到的关于两个群的带循环融合自由积的Frattini子群的一个定理推广到任意多个子群的带循环融合自由积的情况.通过考虑任意多个子群的带循环融合自由积的πnFrattini子群和πcFrattini子群,得到了类似的结果.%Azarian M K generalizes the theorem on Frattini subgroups of amalgamated free products of two subgroups proposed by Tang C Y to the case of the free product of any set of subgroups with amalgamated subgroup. We consider TrnFrattini subgroups and TrcFrattini subgroups of the free product of any set of subgroups with amalgmated subgroup being a cyclic group and obtain similar results.
A new attitude coupled with fuzzy thinking to fuzzy group and subgroup
F. Abbasi
2016-02-01
Full Text Available In this paper, we shall embark on the study of the algebraic object known as a fuzzy group which serves as one of the fundamental building blocks for the subject which is called fuzzy abstract algebra. In our opinion, the fuzzy algebraic systems are usually sets on whose elements we can operate algebraically by this we mean that we can combine two elements of the set, perhaps in several ways, to obtain a third element of the set and, in addition, we assume that these fuzzy algebraic operations are subject to certain rules, which are explicitly spelled out in what we call the axioms or postulates defining the system. In this abstract setting we then attempt to prove theorems about these very general structures. We should like to stress that these fuzzy algebraic systems and their axioms, must come from the experience of looking at many examples. Namely, they should be rich in meaningful results. Hence, the acceptable definition of fuzzy group and subgroup are presented with binary operations and on the basis of the specified parameter, called ambiguity rank, which fulfils the basic requirements. The properties of these fuzzy groups and their fundamental qualities are discussed and then, the several illustrative examples were given. The future prospect of this paper is a new attitude to fuzzy basic mathematics, which will be referred to in the end.
Genetic Sequencing Analysis of A307 Subgroup of ABO Blood Group.
Huang, Ying; Lin, Jiajin; Zhu, Suiyong
2015-09-18
BACKGROUND The aim of this study was to investigate the serology and gene sequence characteristics of the A307 subgroup of the ABO blood group. MATERIAL AND METHODS Monoclonal anti-A and anti-B antibodies were used to detect the ABO antigens of a proband whose positive blood type was not consistent with the negative blood type of the ABO blood group. Standard A-, B-, and O-negative typing cells were used to test for ABO antibodies in the serum. Additionally, polymerase chain reaction with sequence-specific primer (PCR-SSP) was used to confirm the genotype, and subsequently, exons 6 and 7 of the ABO gene were detected by gene sequencing. Samples from the wife and daughters of the proband were also used for serological and genetic testing. RESULTS Red blood cells of the proband showed weak agglutination reaction with anti-A antibody, while anti-B antibody was detected in the serum. Moreover, PCR-SSP detected A307 and O02 alleles, while gene sequencing revealed mutation of c.745C>T in exon 7, which produced a polypeptide chain p.R249W. The A307 gene of the proband was not inherited by his daughters. CONCLUSIONS A mutation (c.745 C>T) in exon 7 of the ABO blood group gene resulted in low activity of a-1,3-N-acetyl-galactosaminyl transferase, producing A3 phenotype.
Genetic sequencing analysis of the A307 subgroup of ABO blood group.
Huang, Ying; Lin, Jiajin; Zhu, Suiyong
2015-01-01
The aim of this study was to investigate the serology and gene sequence characteristics of the A307 subgroup of ABO blood group. Monoclonal anti-A and anti-B antibodies were used to detect the ABO antigens of a proband whose positive blood type was not consistent with the negative blood type of ABO blood group. Meanwhile, standard A-, B-, and O-negative typing cells were used to test for ABO antibodies in the serum. Additionally, polymerase chain reaction with sequence-specific primer (PCR-SSP) was used to confirm the genotype, and subsequently, exons 6 and 7 of the ABO gene were detected by gene sequencing. Samples from the wife and daughters of the proband were also used for serological and genetic testing. Red blood cells of the proband showed weak agglutination reaction with anti-A antibody, while anti-B antibody was detected in the serum. Moreover, PCR-SSP detected A307 and O02 alleles, while gene sequencing revealed mutation of c.745C>T in exon 7, which produced a polypeptide chain p.R249W. Furthermore, the A307 gene of the proband was not inherited by his daughters. A mutation (c.745 C>T) in exon 7 of the ABO blood group gene resulted in low activity of α-1, 3-N-acetyl-galactosaminyl transferase, producing A3 phenotype.
Williams Scott G
2008-04-01
Full Text Available Abstract Purpose To assess whether an expanded (five level risk stratification system can be used to identify the sub-group of intermediate risk patients with prostate cancer who benefit from combining androgen deprivation therapy (ADT with external beam radiotherapy (EBRT. Materials and methods Using a previously validated 5-risk group schema, a prospective non-randomized data set of 1423 men treated at the British Columbia Cancer Agency was assessed for the primary end point of biochemical control (bNED with the RTOG-ASTRO "Phoenix" definition (lowest PSA to date + 2 ng/mL, both with and without adjuvant ADT. The median follow-up was 5 years. Results There was no bNED benefit for ADT in the low or low intermediate groups but there was a statistically significant bNED benefit in the high intermediate, high and extreme risk groups. The 5-year bNED rates with and without ADT were 70% and 73% respectively for the low intermediate group (p = non-significant and 72% and 58% respectively for the high intermediate group (p = 0.002. Conclusion There appears to be no advantage to ADT where the Gleason score is 6 or less and PSA is 15 or less. ADT is beneficial in patients treated to standard dose radiation with Gleason 6 disease and a PSA greater than 15 or where the Gleason score is 7 or higher.
Crowcroft Natasha S
2010-12-01
Full Text Available Abstract Background Encephalitis is an acute clinical syndrome of the central nervous system (CNS, often associated with fatal outcome or permanent damage, including cognitive and behavioural impairment, affective disorders and epileptic seizures. Infection of the central nervous system is considered to be a major cause of encephalitis and more than 100 different pathogens have been recognized as causative agents. However, a large proportion of cases have unknown disease etiology. Methods We perform hierarchical cluster analysis on a multicenter England encephalitis data set with the aim of identifying sub-groups in human encephalitis. We use the simple matching similarity measure which is appropriate for binary data sets and performed variable selection using cluster heatmaps. We also use heatmaps to visually assess underlying patterns in the data, identify the main clinical and laboratory features and identify potential risk factors associated with encephalitis. Results Our results identified fever, personality and behavioural change, headache and lethargy as the main characteristics of encephalitis. Diagnostic variables such as brain scan and measurements from cerebrospinal fluids are also identified as main indicators of encephalitis. Our analysis revealed six major clusters in the England encephalitis data set. However, marked within-cluster heterogeneity is observed in some of the big clusters indicating possible sub-groups. Overall, the results show that patients are clustered according to symptom and diagnostic variables rather than causal agents. Exposure variables such as recent infection, sick person contact and animal contact have been identified as potential risk factors. Conclusions It is in general assumed and is a common practice to group encephalitis cases according to disease etiology. However, our results indicate that patients are clustered with respect to mainly symptom and diagnostic variables rather than causal agents
Use of a fragment of the tuf gene for phytoplasma 16Sr group/subgroup differentiation
Contaldo, Nicoletta; Canel, Alessandro; Makarova, Olga
2011-01-01
The usefulness of RFLP analyses on a 435 bp fragment of the tuf gene for preliminary identification of phytoplasmas from a number of phytoplasma ribosomal groups and/or 'Candidatus. Phytoplasma' was verified. The strains employed belong to thirteen 16Sr DNA groups and 22 different subgroups and w...
MOISEENKOVA; T.; V.; NUZHIN; Ya.; N.
2009-01-01
The Iwasava decomposition is proved for the Steinberg groups of types 2A2l-1, 2Dl, 2E6, 3D4 over the field of fractions of a principal ideal ring. By using this decomposition, it is described that subgroups exist between the Steinberg groups over the rings D and K under some restrictions on the ring D.
Martinussen, Laila Marianne; Møller, Mette; Prato, Carlo Giacomo
2014-01-01
The Driver Behavior Questionnaire and the Driver Skill Inventory are two of the most frequently used measures of self-reported driving style and driving skill. The motivation behind the present study was to identify sub-groups of drivers that potentially act dangerously in traffic (as measured...... by frequency of aberrant driving behaviors and level of driving skills), as well as to test whether the sub-groups differ in characteristics such as age, gender, annual mileage and accident involvement. Furthermore, the joint analysis of the two instruments was used to test drivers’ assessment of their own...... self-reported driving skills and whether the reported skill level was reflected in the reported aberrant driving behaviors. 3908 drivers aged 18–84 participated in the survey. K-means cluster analysis revealed four distinct sub-groups that differed in driving skills and frequency of aberrant driving...
朱静萍
2004-01-01
用F*(G)代替F(G),将文"Finite Groups with Quasinormal Subgroups of Prime Power Order,Acta Math Hungar 89(4),2000,321-326"一文中的主要定理的可解性的假设去除,从而推广了该文的结论.
26 CFR 1.1502-92 - Ownership change of a loss group or a loss subgroup.
2010-04-01
... parent, the common parent (which is treated as a loss corporation) may file the single statement... the common parent, the single statement must identify each loss subgroup parent and state which loss... change of a subsidiary. (b) Determination of an ownership change—(1) Parent change method—(i) Loss...
On Pronormal Minimal Subgroups of Finite Groups%关于有限群的Pronormal极小子群
王坤仁
2004-01-01
利用有限群G的pronormal极小子群和Sylow子群正规化子中的素数阶弱左Engel元素得到了G成为p-幂零群、幂零群和超可解群的一些充分条件,这些结果推广了已知结论.%By using pronormal minimal subgroups and weak left Engel elements of prime order of the normalizers of Sylow subgroups of a finite group G, we obtain some sufficient conditions for G to be p-nilpotent, nilpotent and supersolvable respectively,which generalize some known results.
Couri, M S
2005-11-01
The 11 neotropical species of Fannia belonging to the pusio sub-group (canicularis group), are keyed F. dodgei Seago; F. femoralis (Stein); F. pamplonae Couri & Araújo; F. parafemoralis Araújo & Couri; F. paraisensis Araújo & Couri; F. punctivervis Malloch; F. pusio (Wiedemann); F. sabroskyi Seago; F. snyderi Seago; F. trimaculata (Stein); F. trimaculatoides Couri & Pamplona. The key is addressed only to the males and the illustrations help in the visualization of the characters.
Yanheng Chen; Guiyun Chen
2013-11-01
Let be a finite group, and $n(G)$ be the set of the number of subgroups of possible order of . We investigate the structure of satisfying that $n(G) = \\{1, m\\}$ for any positive integer > 1. At first, we prove that the nilpotent length of is less than 2. Secondly, we investigate nilpotent groups with $m = p + 1$ or $p^2 + p + 1$ ( is a prime), and we get the classification of such kinds of groups. At last, we investigate non-nilpotent groups with $m = p + 1$ and get the classification of the groups under consideration.
Ali Reza Ashrafi; Geetha Venkataraman
2004-08-01
Let be a finite group and be a normal subgroup of . We denote by $ncc(A)$ the number of -conjugacy classes of and is called -decomposable, if $ncc(A)=n$. Set $\\mathcal{K}_G=\\{ncc(A)|A\\vartriangleleft G\\}$. Let be a non-empty subset of positive integers. A group is called -decomposable, if $\\mathcal{K}_G=X$. Ashrafi and his co-authors [1–5] have characterized the -decomposable non-perfect finite groups for $X=\\{1,n\\}$ and ≤ 10. In this paper, we continue this problem and investigate the structure of -decomposable non-perfect finite groups, for $X=\\{1, 2, 3\\}$. We prove that such a group is isomorphic to $Z_6, D_8, Q_8, S_4$, Small Group (20,3), Small Group (24,3), where Small Group (, ) denotes the $m^{\\mathrm{th}}$ group of order in the small group library of GAP [11].
Le, T Domi; Carney, Patricia A; Lee-Lin, Frances; Mori, Motomi; Chen, Zunqiu; Leung, Holden; Lau, Christine; Lieberman, David A
2014-04-01
Asian ethnic subgroups are often treated as a single demographic group in studies looking at cancer screening and health disparities. To evaluate knowledge and health beliefs associated with colorectal cancer (CRC) and CRC screening among Chinese, Korean, and Vietnamese subgroups, a survey assessed participants' demographic characteristics, healthcare utilization, knowledge, beliefs, attitudes associated with CRC and CRC screening. Exploratory factor analysis identified six factors accounting >60 % of the total variance in beliefs and attitudes. Cronbach's alpha coefficients assessed internal consistency. Differences among Asian subgroups were assessed using a Chi square, Fisher's exact, or Kruskal-Wallis test. Pearson's correlation coefficient assessed an association among factors. 654 participants enrolled: 238 Chinese, 217 Korean, and 199 Vietnamese. Statistically significant differences existed in demographic and health care provider characteristics, knowledge, and attitude/belief variables regarding CRC. These included knowledge of CRC screening modalities, reluctance to discuss cancer, belief that cancer is preventable by diet and lifestyle, and intention to undergo CRC screening. Chinese subjects were more likely to use Eastern medicine (52 % Chinese, 25 % Korean, 27 % Vietnamese; p Vietnamese; p Vietnamese subjects were less likely to consider CRC screening (95 % Chinese, 95 % Korean, 80 % Vietnamese; p health beliefs among Asian subgroups. Understanding these differences will enable clinicians to deliver tailored, effective health messages to improve CRC screening and other health behaviors.
Martinussen, Laila Marianne; Møller, Mette; Prato, Carlo Giacomo
based on a combined use of the DBQ and the DSI. Moreover, the joint use of the two instruments was applied to identify sub-groups of drivers that differ in their potential danger in traffic (as measured by frequency of aberrant driving behaviors and level of driving skills), as well as to test whether...... the sub-groups of drivers differed in characteristics such as age, gender, annual mileage and accident involvement. 3908 drivers aged 18–84 participated in the survey. The results suggested that the drivers are consistent in their reporting of driving ability, as the self-reported driving skill level...... mirrored the self-reported frequency of aberrant driving behaviors. K-means cluster analysis revealed four distinct clusters that differed in the frequency of aberrant driving behavior and driving skills, as well as individual characteristics and driving related factors such as annual mileage, accident...
Martinussen, Laila Marianne
with underlying mechanisms of lack of focus, emotional stress, recklessness and confusion, and hence it is highly important to further explore means to making drivers become more focused or attentive when driving, and to deal with emotional responses in traffic like impatience and frustration (Article 1). 2......The aim of the Ph.D. study presented in this thesis was to facilitate improved road safety through increased understanding of methods used to measure driving behaviour, and through increased knowledge about driving behaviour in sub-groups of drivers. More specifically, the usefulness of the Driver...... Behaviour Questionnaire (DBQ) within a Danish context was explored, sub-groups of drivers differing in their potential danger in traffic were identified, and the relationship between implicit attitudes towards safe and risky driving and self-reported driving behaviour was explored. The methods applied were...
极小子群和有限群的结构%Minimal Subgroups and Structures of Finite Groups
王坤仁
2006-01-01
In terms of weak left Engel element and S-seminormal subgroup, some sufficient conditions are given for a finite group to be p-nilpotent or nilpotent or supersolvable.%利用弱左Engel元和S-半正规子群条件给出了有限群成p-幂零群、幂零群和超可解群的一些充分条件.
Wasson, J. T.; Kallemeyn, G. W.
2002-01-01
We present new data or iron meteorites that are members of group IAB or are closely related to this large group, and we have also reevaluated some of our earlier data for these irons. In the past it was not possible to distinguish IAB and IIICD irons on the basis of their positions on element-Ni diagrams. We now find that plotting, the new and revised data yields six sets of compact fields on element-Au diagrams, each set corresponding to a compositional group. The largest set includes the majority (approximately equal to 70) of irons previously designated IA: We christened this set the IAB main group. The remaining five sets we designate subgroups within the IAB complex. Three of these subgroups have Au contents similar to the main group, and form parallel trends in most element-Ni diagrams. The groups originally designated IIIC and IIID are two of these subgroups: they are now well resolved from each other and from the main group. The other low-Au subgroup has Ni contents just above the main group. Two other IAB subgroups have appreciably higher Au contents than the main group and show weaker compositional links to it. We have named these five subgroups on the basis of their Au and Ni contents. The three subgroups having Au contents similar to the main group are the low-Au (L) subgroups the two others the high-Au (H) subgroups. The Ni contents are designated high (H), medium (M), or low (L). Thus the old group IIID is now the sLH subgroup. the old group IIIC is the sLM subgroup. In addition, eight irons assigned to two grouplets plot between sLL and sLM on most element-Au diagrams. A large number (27) of related irons plot outside these compact fields but nonetheless appear to be sufficiently related to also be included in the IAB complex.
Risk groups for yellow fever vaccine-associated viscerotropic disease (YEL-AVD).
Seligman, Stephen J
2014-10-07
Although previously considered as the safest of the live virus vaccines, reports published since 2001 indicate that live yellow fever virus vaccine can cause a severe, often fatal, multisystemic illness, yellow fever vaccine-associated viscerotropic disease (YEL-AVD), that resembles the disease it was designed to prevent. This review was prompted by the availability of a listing of the cumulative cases of YEL-AVD, insights from a statistical method for analyzing risk factors and re-evaluation of previously published data. The purpose of this review is to identify and analyze risk groups based on gender, age, outcome and predisposing illnesses. Using a passive surveillance system in the US, the incidence was reported as 0.3 to 0.4 cases per 100,000. However, other estimates range from 0 to 12 per 100,000. Identified and potential risk groups for YEL-AVD include elderly males, women between the ages of 19 and 34, people with a variety of autoimmune diseases, individuals who have been thymectomized because of thymoma, and infants and children ≤11 years old. All but the last group are supported by statistical analysis. The confirmed risk groups account for 77% (49/64) of known cases and 76% (32/42) of the deaths. The overall case fatality rate is 66% (42/64) with a rate of 80% (12/15) in young women, in contrast to 50% (13/26) in men ≥56 years old. Recognition of YEL-AVD raises the possibility that similar reactions to live chimeric flavivirus vaccines that contain a yellow fever virus vaccine backbone could occur in susceptible individuals. Delineation of risk groups focuses the search for genetic mutations resulting in immune defects associated with a given risk group. Lastly, identification of risk groups encourages concentration on measures to decrease both the incidence and the severity of YEL-AVD.
On Non-commuting Sets in a Finite p-group with Derived Subgroup of Prime Order
Wang Yu-lei; Liu He-guo
2016-01-01
Let G be a finite group. A nonempty subset X of G is said to be non-commuting if xy = yx for any x, y ∈ X with x = y. If |X| ≥ |Y| for any other non-commuting set Y in G, then X is said to be a maximal non-commuting set. In this paper, we determine upper and lower bounds on the cardinality of a maximal non-commuting set in a finite p-group with derived subgroup of prime order.
Martinussen, Laila Marianne; Møller, Mette; Prato, Carlo Giacomo
2014-01-01
The Driver Behavior Questionnaire and the Driver Skill Inventory are two of the most frequently used measures of self-reported driving style and driving skill. The motivation behind the present study was to identify sub-groups of drivers that potentially act dangerously in traffic (as measured by...... driving behaviors, and vice versa. The present findings highlight the need to look into driver’s attitudes towards safety, and to devise differential interventions targeting specific problematic groups of the population in the attempt to improve road safety nationwide....
C. T. A. COSTA
Full Text Available The aim of this work was to characterize the male courtship song pattern of various species of the fasciola subgroup and to determine the level of variation both within and among species. The parameters analyzed were intrapulse interval (PI, interpulse interval (IPI, and intrapulse frequency (IF. Six different species were analyzed: D. coroica (three populations, D. ellisoni, D. fascioloides, D. moju, D. onca, and D. rosinae (one population each. There were significant differences among the six species for these three courtship song parameters. The IPI was the most variable parameter among these species, suggesting that this parameter is important for female discrimination. Four different hypotheses could explain this variation: 1. different selection pressures with absence of flow gene; 2. intraspecific sexual selection; 3. sympatric effects on song evolution; and 4. genetic drift. The PI was the only parameter that was significantly different among the three population of D. coroica. Low variability among populations within the same species was already observed for other subgroups and could be explained by the following hypotheses: strong selection acting on the song parameters, gene flow, or recent colonization from a common source. Additional studies of the courtship song of other species of the fasciola subgroup, as well as for other subgroups of the repleta group, and studies, using molecular makers, that focus on the genetic basis of the differences among these species in courtship song would allow us to evaluate the association of courtship song and sexual isolation in these species, and would also help us to understand the evolution of these behavioural differences.
Johnson, Gary E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
2014-09-01
This document is the annual report for fiscal year 2014 for the project called Facilitation of the Estuary/Ocean Subgroup (EOS) and the Expert Regional Technical Group (ERTG). Pacific Northwest National Laboratory (PNNL) conducted the project for the Bonneville Power Administration. The EOS and ERTG are part of the research, monitoring, and evaluation and habitat restoration efforts, respectively, developed by the Action Agencies (BPA, U.S. Army Corps of Engineers) in response to obligations arising from the Endangered Species Act as a result of operation of the Federal Columbia River Power System and implemented under the Columbia Estuary Ecosystem Restoration Program.
Behnaz Tolue
2018-07-01
Full Text Available In this paper we introduce stable subgroup graph associated to the group $G$. It is a graph with vertex set all subgroups of $G$ and two distinct subgroups $H_1$ and $H_2$ are adjacent if $St_{G}(H_1\\cap H_2\
Avian leukosis virus (ALV) causes high mortality associated with tumor formation and decreased fertility, and results in major economic losses in the poultry industry worldwide. Recently, a putative novel ALV subgroup virus named ALV-K was observed in Chinese local chickens. In this study, a novel A...
Noether's problem for the groups with a cyclic subgroup of index 4
Kang, Ming-chang; Zhou, Jian
2011-01-01
Let $G$ be a finite group and $k$ be a field. Let $G$ act on the rational function field $k(x_g:g\\in G)$ by $k$-automorphisms defined by $g\\cdot x_h=x_{gh}$ for any $g,h\\in G$. Noether's problem asks whether the fixed field $k(G)=k(x_g:g\\in G)^G$ is rational (i.e. purely transcendental) over $k$. Theorem 1. If $G$ is a group of order $2^n$ ($n\\ge 4$) and of exponent $2^e$ such that (i) $e\\ge n-2$ and (ii) $\\zeta_{2^{e-1}} \\in k$, then $k(G)$ is $k$-rational. Theorem 2. Let $G$ be a group of order $4n$ where $n$ is any positive integer (it is unnecessary to assume that $n$ is a power of 2). Assume that {\\rm (i)} $\\fn{char}k \
Nuriye İsmihan Ece Paköz
2013-03-01
Full Text Available Objective: This study was to investigate theeffects of lymphocyte sub-groups of the use ofMaraş powder.Method: This study used healthy volunteers,and no smoking or Maras powder (control groupused healthy volunteers. The blood samples forlymphocyte subsets of the cellular immune systemlymphocyte subsets of antibodies were evaluatedwith Becton Dickinson kits using a flow-cytometrikmethod.Results: Case group averages of CD4+/CD8+ Tcell ratios, CD19+ (B lymphocytes and the meanpercentage of CD4+ T lymphocytes were significantlylower than the control group (p0.05.Conclusions: Maras powder increases thecellular immunity relative in the smoking addictivepeople, while humoral immunity declines.As a result, immune responses that is resultingwith any deviation, predisposing factor for avariety of diseases. Therefore, informing of themaras powder users should be considered for harming their health as smoking as well.
Myrone Christopher Stoffels
2015-12-01
Full Text Available The implementation of affirmative action measures can give rise to unfair discrimination. In cases where members of the “designated groups” compete with one another for the same position, there can be allegations of unfair discrimination. The question arises as to how the employer needs to act in order to avoid unfair discrimination in cases where more than one person from the designated group applies for the same position. The purpose of this article is to evaluate the impact of unfair discrimination on the designated group, specifically with regard to the subgroup “black people” as well as how the employer can avoid unfair discrimination in the implementation of the affirmative action measures aimed at advancing “black people” by selecting the most suitably qualified person from the sub group black people based on the national and regional demographics.
The geometry of right angled Artin subgroups of mapping class groups
Clay, Matt; Mangahas, Johanna
2010-01-01
We describe sufficient conditions which guarantee that a finite set of mapping classes generate a right-angled Artin group quasi-isometrically embedded in the mapping class group. Moreover, under these conditions, the orbit map to Teichmuller space is a quasi-isometric embedding for both of the standard metrics. As a consequence, we produce infinitely many genus h surfaces (for any h at least 2) in the moduli space of genus g surfaces (for any g at least 3) for which the universal covers are quasi-isometrically embedded in the Teichmuller space.
The more, the merrier? Numerical strength versus subgroup distinctiveness in minority groups
Livingstone, Andrew G.; Spears, Russell; Manstead, Antony S. R.; Bruder, Martin
2011-01-01
Evidence attests to the efforts made by minority groups to defend and promote 'distinctive' attributes that potentially define the ingroup. However, these attributes are often only available to a prototypical minority within the minority category. In two studies we tested the hypothesis that, under
Global dimensions for Lie groups at level k and their conformally exceptional quantum subgroups
Coquereaux, Robert
2010-01-01
We obtain formulae giving global dimensions for fusion categories defined by Lie groups G at level k and for the associated module-categories obtained via conformal embeddings. The results can be expressed in terms of Lie quantum superfactorials of type G. The later are related, for the type Ar, to the quantum Barnes function.
Sulman, E.M.; Kosivtsov, Y.Y.; Lugovoy, Y.V. [Tver Technical University, Tver (Russian Federation)
2008-07-01
The purpose of this investigation is the study of activity of iron sub-group metal chlorides in co-processing of peat and polymeric wastes by low-temperature catalytic pyrolysis method. Iron sub-group metal chlorides in concentration varied from 1 to 10% (wt) were used as the catalysts of pyrolysis. The process was conducted in fixed bed reactor in inert gaseous atmosphere at the temperature interval of 350-550{sup o}C. All the investigated catalysts were found to promote the increase of liquid fraction mass and the decrease of solid carbon-containing residue mass up to 10-30%. Cobalt catalyst revealed the highest selectivity with respect to liquid products formation. The use of the catalysts in low-temperature peat and polymeric wastes pyrolysis process was found to favour the increase gaseous products volume up to 20-50% as well as unsaturated hydrocarbons volume in 1.2 folds in comparison to uncatalysed process. 9 refs., 3 figs., 2 tabs.
Maximal Abelian subgroups of the isometry and conformal groups of Euclidean and Minkowski spaces
Thomova, Z.; Winternitz, P.
1998-02-01
The maximal Abelian subalgebras (MASAs) of the Euclidean 0305-4470/31/7/016/img1 and pseudo-euclidean 0305-4470/31/7/016/img2 Lie algebras are classified into conjugacy classes under the action of the corresponding Lie groups 0305-4470/31/7/016/img3 and 0305-4470/31/7/016/img4, and also under the conformal groups 0305-4470/31/7/016/img5 and 0305-4470/31/7/016/img6, respectively. The results are presented in terms of decomposition theorems. For 0305-4470/31/7/016/img1 orthogonally indecomposable MASAs exist only for p = 1 and p = 2. For 0305-4470/31/7/016/img2, on the other hand, orthogonally indecomposable MASAs exist for all values of p. The results are used to construct new coordinate systems in which wave equations and Hamilton-Jacobi equations allow the separation of variables.
Devonian (Emsian-Eifelian) fish from the Lower Bokkeveld Group (Ceres Subgroup), South Africa
Anderson, M. E.; Almond, J. E.; Evans, F. J.; Long, J. A.
1999-07-01
Four major groups of fish are represented by fragmentary remains from South Africa's Lower Bokkeveld Group of Early to Middle Devonian age: the Acanthodii, Chondrichthyes, Placodermi and Osteichthyes. These represent the oldest known occurrences of these groups in southern Africa, as well as an important addition to the very meagre record of earlier Devonian fish from the Malvinokaffric Province of southwestern Gondwana. Bokkeveld fish material comes from the Gydo (Late Emsian) and Tra Tra (Middle Eifelian) Formations of the Western Cape and Eastern Cape Provinces. The cosmopolitan marine acanthodian Machæracanthus is represented only by isolated fin spines which may belong to two different species on the basis of their external ornamentation, cross-sectional outline and internal histology. The elasmobranchs are represented by four elements: (1) a flattened chondrocranium which bears affinity to the Late Devonian-Carboniferous symmoriid (protacrodont) 'cladodont' sharks. It is probably the earliest known (Emsian) shark chondrocranium; (2) an isolated, primitive scapulocoracoid with a very short coracoidal ridge; (3) ankylosed and isolated radials, interpreted as parts of pterygial plates of a paired fin of an unknown chondrichthyan bearing affinity to the Middle Devonian Zamponiopteron from Bolivia; and (4) isolated barlike structures, perhaps gill arch or a jaw elements, thought to be from the same taxon as (3). The placoderms are represented by an incomplete trunk armour and fragmentary, finely ornamented plates of a primitive antiarch. The Osteichthyes are represented by a single large scale of an unidentified dipnoan from the Eifelian of the Cedarberg range, as well as a probable sarcopterygian dermal plate from the Emsian of the Prince Albert area. These are among the earliest sarcopterygian remains recorded from the Malvinokaffric Province.
Watari, Ricky; Kobsar, Dylan; Phinyomark, Angkoon; Osis, Sean; Ferber, Reed
2016-10-01
Not all patients with patellofemoral pain exhibit successful outcomes following exercise therapy. Thus, the ability to identify patellofemoral pain subgroups related to treatment response is important for the development of optimal therapeutic strategies to improve rehabilitation outcomes. The purpose of this study was to use baseline running gait kinematic and clinical outcome variables to classify patellofemoral pain patients on treatment response retrospectively. Forty-one individuals with patellofemoral pain that underwent a 6-week exercise intervention program were sub-grouped as treatment Responders (n=28) and Non-responders (n=13) based on self-reported measures of pain and function. Baseline three-dimensional running kinematics, and self-reported measures underwent a linear discriminant analysis of the principal components of the variables to retrospectively classify participants based on treatment response. The significance of the discriminant function was verified with a Wilk's lambda test (α=0.05). The model selected 2 gait principal components and had a 78.1% classification accuracy. Overall, Non-responders exhibited greater ankle dorsiflexion, knee abduction and hip flexion during the swing phase and greater ankle inversion during the stance phase, compared to Responders. This is the first study to investigate an objective method to use baseline kinematic and self-report outcome variables to classify on patellofemoral pain treatment outcome. This study represents a significant first step towards a method to help clinicians make evidence-informed decisions regarding optimal treatment strategies for patients with patellofemoral pain. Copyright © 2016 Elsevier Ltd. All rights reserved.
Urban road traffic deaths: data linkage and identification of high-risk population sub-groups
Lúcia Maria Miana Mattos Paixão
2015-11-01
Full Text Available Abstract This study analyzes the profile of deaths from road traffic accidents in Belo Horizonte, Minas Gerais State, Brazil, by linking two public databases, the Information System of the Urban Transportation and Transit Company (BH10 and the Mortality Information System (SIM. The linked database (n = 306 identified a 24% under-recording rate for deaths and differed in the age distribution from the BH10 database and in roadway user category when compared to the mortality database. The mortality rate for road traffic accidents within the city limits was 10.2 per 100,000 thousand, and was higher among men, young adults, and the elderly. Poisson multivariate regression showed a higher mean death rate for motorcycle occupants (rate ratio – RR: 1.81; pedestrians (RR: 1.32; males (RR: 1.24; single/divorced (RR: 1.27; young adults 18-29 years of age (RR: 1.75; elderly (RR: 1.59; and deaths at the crash site (RR: 1.39 when compared to the reference categories. The study unveils the city’s traffic violence, expressed by the large proportion of deaths at the crash site and within the first 24 hours, and confirms the relevance of database linkage for characterizing vulnerable groups and traffic accident mortality in the urban setting.
V.M. Fedorchuk
2008-11-01
Full Text Available It is established which functional bases of the first-order differential invariants of the splitting and non-splitting subgroups of the Poincaré group $P(1,4$ are invariant under the subgroups of the extended Galilei group $widetilde G(1,3 subset P(1,4$. The obtained sets of functional bases are classified according to dimensions.
Johnson, Gary E.; Sather, Nichole K.
2013-10-30
This project covers facilitation of the Estuary/Ocean Subgroup (EOS) for federal research, monitoring, and evaluation (RME) and the Expert Regional Technical Group (ERTG) for estuary habitat restoration. The EOS is part of the research, monitoring, and evaluation effort that the Action Agencies (Bonneville Power Administration [BPA], U.S. Army Corps of Engineers [Corps], U.S. Bureau of Reclamation) developed in response to obligations arising from the Endangered Species Act as applied to operation of the Federal Columbia River Power System (FCRPS). The EOS is tasked by National Marine Fisheries Service (NMFS) and the Action Agencies (AAs) to design and coordinate implementation of the federal RME plan for the lower Columbia River and estuary, including the river’s plume in the ocean. Initiated in 2002, the EOS is composed of members from BPA, the Corps, NMFS, and Pacific Northwest National Laboratory’s (PNNL’s) Marine Sciences Laboratory, and other agencies as necessary.
Tóth, Zoltán; Griggio, Matteo
2011-01-01
Social network theory provides a perfect tool to better understand the population-level consequences of how individuals interact and make their decisions; however, this approach is generally overlooked among evolutionary biologists interested in social relationships. Here, we used social network analysis to examine the patterns of leader-follower interactions in relation to individual characteristics in foraging groups of free-living rock sparrows (Petronia petronia). We found that yellow feather ornamentation, a carotenoid-based trait, was the best predictor of leadership: birds with bigger ornaments exerted greater influence in the foraging groups and were followed by more group-mates than less elaborate individuals. An individual's tendency for eliciting followings was not influenced by sex, condition or the level of parental investment. None of the above individual characteristics had significant effect on the tendency of individuals to follow others. Our results indicate that a sexually selected trait can also play a significant role in group coordination and social organization of a species.
Zoltán Tóth
Full Text Available Social network theory provides a perfect tool to better understand the population-level consequences of how individuals interact and make their decisions; however, this approach is generally overlooked among evolutionary biologists interested in social relationships. Here, we used social network analysis to examine the patterns of leader-follower interactions in relation to individual characteristics in foraging groups of free-living rock sparrows (Petronia petronia. We found that yellow feather ornamentation, a carotenoid-based trait, was the best predictor of leadership: birds with bigger ornaments exerted greater influence in the foraging groups and were followed by more group-mates than less elaborate individuals. An individual's tendency for eliciting followings was not influenced by sex, condition or the level of parental investment. None of the above individual characteristics had significant effect on the tendency of individuals to follow others. Our results indicate that a sexually selected trait can also play a significant role in group coordination and social organization of a species.
Gao, Shichun; Dong, Qianjin; Fu, Xiang; Ai, Ze
2010-05-01
The cascaded reservoir group in upper Yellow River has the integrated function of ice jam flood prevention and power generation. The main factors which affect the utilization of the ice jam flood prevention volume of Liujiaxia reservoir are analyzed during the period of ice jam flood prevention, based on the input of new power station in upper Yellow River, the method of cascaded compensating scheduling are applied and the relation curve between the ice jam flood prevention volume and the cascaded output power of Liujiaxia reservoir is calculated, and the scheduling multi-objective solution set for the reservoir is obtained. On this basis, the new scheduling mode solving the reservoir integrated scheduling problem in upper Yellow River during the period of ice jam flood prevention is discussed. Comparing with the regular scheduling results, the new scheduling mode based on multi-objective solution set has the outstanding advantage in solving the problem of multi-objective scheduling of cascaded reservoir group.
Colmant, Agathe M G; Bielefeldt-Ohmann, Helle; Hobson-Peters, Jody; Suen, Willy W; O'Brien, Caitlin A; van den Hurk, Andrew F; Hall, Roy A
2016-05-01
A novel flavivirus, provisionally named Bamaga virus (BgV), was isolated from Culex annulirostris mosquitoes collected from northern Australia. Phylogenetic analysis of the complete nucleotide sequence of the BgV genome revealed it clustered with the yellow fever virus (YFV) group, and was most closely related to Edge Hill virus (EHV), another Australian flavivirus, with 61.9% nucleotide and 63.7% amino acid sequence identity. Antigenic analysis of the envelope and pre-membrane proteins of BgV further revealed epitopes common to EHV, dengue and other mosquito-borne flaviviruses. However, in contrast to these viruses, BgV displayed restricted growth in a range of vertebrate cell lines with no or relatively slow replication in inoculated cultures. There was also restricted BgV replication in virus-challenged mice. Our results indicate that BgV is an evolutionary divergent member of the YFV group of flaviviruses, and represents a novel system to study mechanisms of virus host-restriction and transmission.
Miyashita, Toshikazu
2010-01-01
For simply connected compact exceptional Lie groups $G = F_4, E_6$ and $E_7$, we consider two involutions $\\sigma, \\gamma$ and determine the group structure of subgroups $G^{\\sigma,\\gamma}$ of $G$ which are the intersection $G^\\sigma \\cap G^{\\gamma}$ of the fixed points subgroups of $G^\\sigma$ and $G^{\\gamma}$. The motivation is as follows. In [1](see the References of this paper), we determine the group structure of $(F_4)^{\\sigma, \\sigma'}, (E_6)^{\\sigma, \\sigma'}$ and $(E_7)^{\\sigma, \\sigm...
Najera Catalan, Hector E
2017-01-01
Material deprivation is represented in different forms and manifestations. Two individuals with the same deprivation score (i.e. number of deprivations), for instance, are likely to be unable to afford or access entirely or partially different sets of goods and services, while one individual may fail to purchase clothes and consumer durables and another one may lack access to healthcare and be deprived of adequate housing . As such, the number of possible patterns or combinations of multiple deprivation become increasingly complex for a higher number of indicators. Given this difficulty, there is interest in poverty research in understanding multiple deprivation, as this analysis might lead to the identification of meaningful population sub-groups that could be the subjects of specific policies. This article applies a factor mixture model (FMM) to a real dataset and discusses its conceptual and empirical advantages and disadvantages with respect to other methods that have been used in poverty research . The exercise suggests that FMM is based on more sensible assumptions (i.e. deprivation covary within each class), provides valuable information with which to understand multiple deprivation and is useful to understand severity of deprivation and the additive properties of deprivation indicators.
Yu-Wei Tsai
2010-01-01
Full Text Available The Chihsingshan Volcano Subgroup (CVSG is one of the most important landforms located within the Tatun Volcano Group in northern Taiwan. Based on a Digital Terrain Model, contour maps and field investigations, the CVSG can be divided into four types of volcanic landforms: (1 a strato- or composite volcano, Chihsingshan; (2 domes, the Shamaoshan and a hidden unit; (3 lava cones, the Baiyunshan and the Hsiaotsaoshan; and (4 a scoria cone, the Chikushan. Meanwhile, many small craters are distributed linearly along two northeast trending normal-fault systems. The occurrences are predominantly lava flows with subsidiary fall deposits, pyroclastic flows, and lahars in which at least twenty layers of lava flow in the CVSG can be recognized. Among them, 16 layers in the Chihsingshan volcano, named as C1 - C16, two in the Baiyunshan, B1 - B2, and two in the Hsiaotsaoshan, H1 - H2. Our study suggests that the potential volcanic hazards include lava and pyroclastic flows and simultaneous or subsequent lahars, if the Chihsingshan erupts in a similar manner as in the past. A volcanic hazard zonation map can be constructed for the purpose of mitigation assuming the future eruptive center and eruptive volume.
ZHAO Xiang; LIN Tiao; CAI Xun-zi; YAN Shi-gui
2011-01-01
Background It is well accepted that the minimally invasive surgery (MIS) for total hip arthroplasty (THA) should combine with less or no muscle damage and is different from mini-incision technique and MIS should have better outcomes than mini-incision surgery.The aim of current analysis was to apply an explicitly defined sub-group analysis to confirm whether this hypothesis is true.Methods A computerized literature search was applied to find any data concerning MIS or mini-incision THAs.A multistage screening was then performed to identify randomized studies fulfilling the inclusive criteria for the analysis.The data were extracted,and sub-group analyses of MIS or mini-incision surgery for different kinds of outcomes were carried out.The P(sub) value for difference between MIS sub-group and mini-incision sub-group was also calculated.Results Eleven studies that fulfilling the inclusion criteria were included,with 472 cases in the study group (MIS or mini-incision) and 492 cases in the conventional group.The overall analysis showed the study group would achieve less surgical duration (P=0.037),intraoperative blood (P ＜0.001) and incision length (P ＜0.001) than conventional group.The difference between sub-groups showed,the MIS would achieve shorter incision length (P(sub) ＜0.05) and bigger cup abduction angle (P(sub) ＜0.05),and cause more blood loss (P (sub) ＜0.05) than mini-incision technique.Other indexeswere comparable between the two sub-groups.Conclusions Though further high quality studies are still needed,the result of current analysis offered an initial conclusion that MIS THA failed to achieve a better clinical outcome than mini-incision technique.The exact definition of MIS still needs to be improved.
Tasnim, Abd Razak; Allia, Shahril; Edinur, Hisham Atan; Panneerchelvam, Sundararajulu; Zafarina, Zainuddin; Norazmi, Mohd Nor
2016-08-01
The earliest settlers in Peninsular Malaysia are the Orang Asli population, namely Semang, Senoi and Proto Malays. In the present study, we typed the HLA-A, -B and -DRB1 loci of the Kensiu and Semai Orang Asli sub-groups. Sequence-based HLA typing was performed on 59 individuals from two Orang Asli sub-groups. A total of 11, 18 and 14 HLA-A, -B and -DRB1 alleles were identified, respectively. These data are available in the Allele Frequencies Net Database under the population name "Malaysia Kedah Kensiu" and "Malaysia Pahang Semai".
Eriksen, N H; Hartzen, S H; Bangsborg, Jette Marie
1994-01-01
During the period 1961-91 a total of 567,635 strains of Staphylococcus aureus from hospitalized patients in Denmark have been characterized according to their antibiotic resistance, site of isolation and phage type. Strains of phage group II (typed by the phages 3A, 3C, 55 and 71) have been...... analysed further. The occurrence of group II strains was relatively constant (approximately 16%) from 1961 until 1983. Since then the frequency of group II strains increased; in 1991 they accounted for 22.7% of all S. aureus strains isolated. Strains of group II can, on the basis of their phage types......, be divided in four subgroups: 3A, 71, 71+ and the 'rest of group II'. Furthermore, within these groups strains may differ from one another in respect to their sensitivity to phages. The increased isolation of group II strains during recent years was because of an increase in strains of subgroups 71...
Johnson, Gary E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
2015-08-01
This document is the annual report for the period September 1, 2014 through August 31, 2015 for the project—Facilitation of the Estuary/Ocean Subgroup (EOS) and the Expert Regional Technical Group (ERTG). Pacific Northwest National Laboratory (PNNL) conducted the project for the Bonneville Power Administration (BPA). The EOS and ERTG are part of the research, monitoring, and evaluation (RME) and habitat restoration efforts, respectively, developed by the Action Agencies (BPA, U.S. Army Corps of Engineers [Corps or USACE], and U.S. Bureau of Reclamation) in response to obligations arising from the Endangered Species Act as a result of operation of the Federal Columbia River Power System (FCRPS) and implemented under the Columbia Estuary Ecosystem Restoration Program (CEERP). BPA/Corps (2015) explain the CEERP and the role of RME and the ERTG. For the purposes of this report, the lower Columbia River and estuary (LCRE) includes the floodplain from Bonneville Dam down through the lower river and estuary into the river’s plume in the ocean. The main purpose of this project is to facilitate EOS and ERTG meetings and work products. Other purposes are to provide technical support for CEERP adaptive management, CEERP restoration design challenges, and tributary RME. From 2002 through 2008, the EOS worked to design the federal RME program for the estuary/ocean (Johnson et al. 2008). From 2009 to the present day, EOS activities have involved RME implementation; however, EOS activities were minimal during the current reporting period. PNNL provided technical support to CEERP’s adaptive management process by convening 1.2 meetings of the Action Agencies (AAs) and drafting material for the “CEERP 2015 Restoration and Monitoring Plan” (BPA/Corps 2015).
Rajiv Yadav
2015-01-01
Full Text Available Introduction: Many healthy elderly Indian men seek surgical treatment for localized prostate cancer. Quite often, radical surgery is not offered to the patients over 70 years of age due to the perception of increased side-effects and complications. We have previously reported our results of robotic radical prostatectomy in a study comprising 150 Indian patients, where almost a quarter of patients were elderly. This subgroup analysis was therefore focused on evaluating perioperative and continence outcomes in elderly men (≥70 years with localized prostate cancer. Materials and Methods: Between April 2010 and August 2013, 153 men had robot-assisted radical prostatectomy performed by two surgeons. Of the 150 men analyzed, 39 (26% were aged ≥70 years. All patients underwent robotic prostatectomy using a 4 arm da Vinci surgical system. Pre-operative, intraoperative and post-operative parameters were studied. Check cystogram was performed in all patients prior to catheter removal. Complications were categorized using the Clavien-Dindo classification system. Continence was defined as use of "no pad" or security liner only. All data were recorded prospectively and analyzed using SPSS version 20. Results: There were no significant intraoperative or perioperative complications in this group. Median blood loss during surgery was 150 mL. None of the patient required blood transfusion. There were two minor complications (5.1% within the first 30 days of surgery: Minimal anastomotic site leak (one patient requiring replacement and prolongation of Foley′s drainage by 1 week and ileus (one patient. No patient had any cardiopulmonary or vascular complications in the post-operative period. The median duration of hospital stay was 3 days. The median duration of catheterization was 7 days. No patient had problem of bladder neck stenosis in the follow-up period. At 1 month, 3 months, 6 months and 1 year of follow-up, 66.7% (n = 26, 74.3% (n = 29, 87.9% (n = 34
The Congruence Subgroup Problem
M S Raghunathan
2004-11-01
This is a short survey of the progress on the congruence subgroup problem since the sixties when the first major results on the integral unimodular groups appeared. It is aimed at the non-specialists and avoids technical details.
Levaillant, Claire
2014-07-01
We study a subgroup Fr(162 × 4) of SU(3) of order 648 which is an extension of D(9, 1, 1; 2, 1, 1) and whose generators arise from anyonic systems. We show that this group is isomorphic to a semi-direct product ( {Z}/18 {Z}\\times {Z}/6 {Z})\\rtimes S_3 with respect to conjugation and we give a presentation of the group. We show that the group D(18, 1, 1; 2, 1, 1) from the series (D) in the existing classification for finite SU(3)-subgroups is also isomorphic to a semi-direct product ( {Z}/18 {Z}\\times {Z}/6 {Z})\\rtimes S_3, with respect to conjugation. We next exhibit the isomorphism between both groups. We prove that Fr(162 × 4) is not isomorphic to the exceptional SU(3) subgroup Σ(216 × 3) of the same order 648. We further prove that the only SU(3) finite subgroups from the 1916 classification by Blichfeldt or its extended version, in which Fr(162 × 4) may be isomorphic, belong to the (D)-series. Finally, we show that Fr(162 × 4) and D(18, 1, 1; 2, 1, 1) are both conjugate under the orthogonal matrix which we provide.
"具有幂零局部子群的有限群"一文的注记%Notes on "Finite Groups with Nilpotent Local Subgroups"
李样明
2008-01-01
A finite group G is called PN-group if G is not nilpotent and for every p-subgroup P of G, there holds that either P is normal in G or P C Z∞(G) or NG(P) is nilpotent, p ∈π(G).In this paper, we prove that PN-group is meta-nilpotent, especially, PN-group is solvable. In addition, we give an elementary, intuitionistie, compact proof of the structure theorem of PN-group.
European Committee for Future Accelerators (ECFA)
1982-01-01
This document contains two reports on the use of microprocessors in European High-Energy Physics experiments. The first is a presentation of data collected by a sub-group of the ECFA working group on data procesing standards. The working group is organised by E. Lillestol, University of Bergen and E.M. Rimmer, CERN, DD Division; the Microprocessor sub-group organiser is L.O. Hertzberger, NIKHEF, Amsterdam. Data are given from projects numbered 81 - 194, and some CERN projects are included. Even though there is some duplication of information, a second report has been appended which covers a wider range of CERN projects. This was the result of a microprocessor survey made at CERN by P. Scharff-Hansen, DD Division, at the request of E. Gabthuler. The ECFA working group intends to have reports for all the sub-groups (10 in number) available in machine-readable form at the CERN computer centre. However, it was felt that the information herein is most valuable to designers and users of microprocessors, and that it...
Herfort, Wolfgang; Zapata, Theo
2011-01-01
Let G be a finitely generated infinite pro-p group acting on a pro-p tree such that the restriction of the action to some open subgroup is free. Then we prove that G splits as a pro-p amalgamated product or as a pro-p HNN-extension over an edge stabilizer. Using this result we prove under certain conditions that free pro-p products with procyclic amalgamation inherit from its free factors the property of each 2-generated subgroup being free pro-p. This generalizes known pro-p results, as well as some pro-p analogs of classical results in abstract combinatorial group theory.
Virtual Amalgamation of Relatively Quasiconvex Subgroups
Martinez-Pedroza, Eduardo
2012-01-01
For relatively hyperbolic groups, we investigate conditions guaranteeing that the subgroup generated by two relatively quasiconvex subgroups $Q_1$ and $Q_2$ is relatively quasiconvex and isomorphic to $Q_1 \\ast_{Q_1 \\cap Q_2} Q_2$. The main theorem extends results for quasiconvex subgroups of word-hyperbolic groups, and results for discrete subgroups of isometries of hyperbolic spaces.
Large group intervention for military reintegration: peer support & Yellow Ribbon enhancements.
Castellano, Cherie; Everly, George S
2010-01-01
University Behavioral HealthCare, University of Medicine and Dentistry of New Jersey in partnership with the New Jersey Department of Military & Veterans Affairs established a program entitled the "New Jersey Veterans Helpline," modeled after the "Cop 2 Cop Helpline," in 2005 to assist veterans and their families within the state. The events of September 11, 2001, demanded an unprecedented response to address the behavioral health care needs of first responders in New Jersey and highlighted the similarities amongst the military population in their response. Although the New Jersey Veterans Helpline program was initiated as a peer based helpline, the need for support in pre- and post-deployment quickly emerged. This paper describes the application of the Cop 2 Cop interventions with the Port Authority Police Department (PAPD) entitled "Acute Stress Management Reentry Program." This program was adapted and combined with Yellow Ribbon Guideline enhancements to create a "60 Day Resiliency & Reintegration Program" led by the New Jersey Veterans program to over 2,400 soldiers returning from war.
Use of a fragment of the tuf gene for phytoplasma 16Sr group/subgroup differentiation
Contaldo, Nicoletta; Canel, Alessandro; Makarova, Olga
2011-01-01
and were obtained from both experimentally and naturally infected plants. The combined RFLP patterns obtained with the three restriction enzymes employed allow the distinction of a total of 18 different profiles, however no discrimination was provided for some of the ribosomal groups for which sequencing...
Ullmann, S Heidi; Goldman, Noreen; Pebley, Anne R
2013-08-01
In recent decades there has been an increasing interest in understanding the role of social and physical contexts in influencing health behaviors and outcomes. This is especially true for weight, which is considered to be highly dependent on environmental factors. The evidence linking neighborhood characteristics to weight in the United States, however, is mixed. Many studies in this area are hampered by cross sectional designs and a limited scope, insofar as they investigate only one dimension of neighborhood context. It is also unclear to what extent neighborhood characteristics account for racial/ethnic disparities in weight. Using longitudinal data from the Los Angeles Family and Neighborhood Survey (L.A. FANS), we compare patterns of weight change between Hispanics and other racial and ethnic groups in order to evaluate whether we observe a pattern of unhealthy assimilation in weight among Hispanic immigrants and to identify differences in the rate at which different groups gain weight over time. We also explore the extent to which patterns of weight change are related to a wider range of community characteristics. We find that weight increases across all groups between the two study waves of L.A. FANS and that the increases are significant except for Asians/Pacific Islanders. With respect to differences in the pace of weight change, second and higher generation Hispanic women and black men gain weight more rapidly than their first generation Hispanic counterparts. Although the evidence presented indicates that first generation Hispanics gain weight, we do not find evidence for convergence in weight since the U.S.-born gain weight at a more rapid rate. The inclusion of community-level variables does not alter the relationships between the race, ethnicity, and immigrant generation categories and weight change. Of the six types of community characteristics considered, only collective efficacy is consistently and significantly associated with weight change
Sadler, Georgia Robins; Lee, Hau-Chen; Seung-Hwan Lim, Rod; Fullerton, Judith
2011-01-01
Nurse researchers and educators often engage in outreach to narrowly defined populations. This article offers examples of how variations on the snowball sampling recruitment strategy can be applied in the creation of culturally appropriate, community-based information dissemination efforts related to recruitment to health education programs and research studies. Examples from the primary author’s program of research are provided to demonstrate how adaptations of snowball sampling can be effectively used in the recruitment of members of traditionally underserved or vulnerable populations. The adaptation of snowball sampling techniques, as described in this article, helped the authors to gain access to each of the more vulnerable population groups of interest. The use of culturally sensitive recruitment strategies is both appropriate and effective in enlisting the involvement of members of vulnerable populations. Adaptations of snowball sampling strategies should be considered when recruiting participants for education programs or subjects for research studies when recruitment of a population based sample is not essential. PMID:20727089
On Complements of Normal Subgroups in Finite Groups Ⅱ%关于有限群的正规子群的补子群Ⅱ
王坤仁
2004-01-01
研讨了关于有限群G的一个正规子群K的补子群之存在性与共轭性的更多一些的结果.主要结果如下:(1)假设K是Abel群并且K的每个Sylow子群S在G之含S的Sylow子群中有补子群.则有:(i)K在G中有补子群;(ii)若G有Hallπ-子群H,其中π=π(K),并且K在H中的所有补子群在H中是共轭的,则K在G中的所有补子群在G中是共轭的.(2)假设K是可解的并且对所有的S/K∈Syl(G/K),K是S的一个直因子.则有:(i)K在G中有补子群;(ii)若G有Hallπ-子群H,其中π＝π(K),则K在G中的所有补子群在G中共轭的充要条件是K在H中的所有补子群在H中共轭.%In this paper, some more properties of the existence and conjugacy of complements of a normal subgroup K of a finite group G are studied. The main results are as follows. (1) Suppose that K is abelian and every Sylow subgrop S of K has a complement in a Sylow subgroup of G which contains S. Then: (i) K has a complement in G; (ii) If G has a Hall π- subgroup H with π = π(K), and all complements of K in H are conjugate in H, then all complements of K in G are conjugate in G. (2) Suppose that K is solvable and K is a direct factor of S for each S/K∈ Syl(G/K).Then: (i) K has a complement in G;(ii) If G has a Hall π-subgroup H with π = π(K), then all complements of K inG are conjugate in G ff and only if all complements of K in H are conjugate in H.
海进科; 李正兴
2013-01-01
设G是一个有限群,通过考虑G的Sylow p-子群的结构,证明了如果G/F*(G)无主因子同构于Cp,则G的Coleman外自同构群是p’-群.%Let G be a finite group.It is proved that if G/F* (G) has no chief factor isomorphic to Cp,then the Coleman outer automorphism group of G is a p'-group by considering the structure of Sylow p-subgroups of G.
New Star in Yellow River Delta --Daming Group Co.,Ltd,Shengli Oilfield
Guo Shuren
1994-01-01
@@ Daming Group Co.,Ltd.,Shengli Oilfield is a high set-off,pluralized and multioriented limited-liability company which was initiated and established by four units of Shengli Petroleum Administration,CNPC,Dongsheng Petroleum Development Co.,Ltd.,Shengli Oilfield,Zhongyuan Company of Dongying Branch,Bank of China,and Shengli Oilfield Labour Service Company,It is the first share-system enterprise in China's petroleum industry.Its total capital is 120 million yuan (RMB).The Shengli Petroleum Administration,CNPC is the biggest shareholder occupying more than 20% of the total capital.
Pearce, Eiluned; Launay, Jacques; van Duijn, Max; Rotkirch, Anna; David-Barrett, Tamas; Dunbar, Robin I M
2016-11-01
Singing together seems to facilitate social bonding, but it is unclear whether this is true in all contexts. Here we examine the social bonding outcomes of naturalistic singing behaviour in a European university Fraternity composed of exclusive 'Cliques': recognised sub-groups of 5-20 friends who adopt a special name and identity. Singing occurs frequently in this Fraternity, both 'competitively' (contests between Cliques) and 'cooperatively' (multiple Cliques singing together). Both situations were re-created experimentally in order to explore how competitive and cooperative singing affects feelings of closeness towards others. Participants were assigned to teams of four and were asked to sing together with another team either from the same Clique or from a different Clique. Participants (N = 88) felt significantly closer to teams from different Cliques after singing with them compared to before, regardless of whether they cooperated with (singing loudly together) or competed against (trying to singing louder than) the other team. In contrast, participants reported reduced closeness with other teams from their own Clique after competing with them. These results indicate that group singing can increase closeness to less familiar individuals regardless of whether they share a common motivation, but that singing competitively may reduce closeness within a very tight-knit group.
Pearce, Eiluned; Launay, Jacques; van Duijn, Max; Rotkirch, Anna; David-Barrett, Tamas; Dunbar, Robin I M
2016-01-01
Singing together seems to facilitate social bonding, but it is unclear whether this is true in all contexts. Here we examine the social bonding outcomes of naturalistic singing behaviour in a European university Fraternity composed of exclusive ‘Cliques’: recognised sub-groups of 5-20 friends who adopt a special name and identity. Singing occurs frequently in this Fraternity, both ‘competitively’ (contests between Cliques) and ‘cooperatively’ (multiple Cliques singing together). Both situations were re-created experimentally in order to explore how competitive and cooperative singing affects feelings of closeness towards others. Participants were assigned to teams of four and were asked to sing together with another team either from the same Clique or from a different Clique. Participants (N = 88) felt significantly closer to teams from different Cliques after singing with them compared to before, regardless of whether they cooperated with (singing loudly together) or competed against (trying to singing louder than) the other team. In contrast, participants reported reduced closeness with other teams from their own Clique after competing with them. These results indicate that group singing can increase closeness to less familiar individuals regardless of whether they share a common motivation, but that singing competitively may reduce closeness within a very tight-knit group. PMID:27777494
Sugimoto, Dai; Myer, Gregory D.; Barber Foss, Kim D.; Hewett, Timothy E.
2014-01-01
Background Although a series of meta-analysis demonstrated neuromuscular training (NMT) is an effective intervention to reduce anterior cruciate ligament (ACL) injury in female athletes, the potential existence of a dosage effect remains unknown. Objective To systematically review previously published clinical trials and evaluate potential dosage effects of NMT for ACL injury reduction in female athletes. Design Meta- and Sub-group analyses Setting The key words “knee”, “anterior cruciate ligament”, “ACL”, “prospective”, “neuromuscular”, “training”, “female”, and “prevention” were utilized in PubMed and EBSCO host for studies published between 1995 and May 2012. Participants Inclusion criteria set for studies in the current analysis were: 1) recruited female athletes as subjects, 2) documented the number of ACL injuries, 3) employed a NMT intervention aimed to reduce ACL injuries, 4) had a control group, 5) used a prospective control trial design and 6) provided NMT session duration and frequency information. Main outcome measures The number of ACL injuries and female athletes in each group (control and intervention) were compared based on duration, frequency, and volume of NMT through odds ratio (OR). Results A total of 14 studies were reviewed. Analyses that compared the number of ACL injuries with short versus long NMT duration showed greater ACL injury reduction in female athletes who were in the long NMT duration (OR:0.35, 95%CI: 0.23, 0.53, p=0.001) than the short NMT duration (OR: 0.61, 95%CI: 0.41, 0.90, p=0.013) group. Analysis that compared single versus multi NMT frequency indicated greater ACL injury reduction in multi NMT frequency (OR: 0.35, 95%CI: 0.23, 0.53, p=0.001) compared to single NMT frequency (OR: 0.62, 95%CI:0.41, 0.94, p=0.024). Combining the duration and frequency of NMT programs, an inverse dose-response association emerged among low (OR: 0.66, 95%CI: 0.43, 0.99, p=0.045), moderate (OR: 0.46, 95%CI: 0.21, 1
Wang, Frédéric
2010-01-01
We give an overview of the Hidden Subgroup Problem (HSP) as of July 2010, including new results discovered since the survey of arXiv:quant-ph/0411037v1. We recall how the problem provides a framework for efficient quantum algorithms and present the standard methods based on coset sampling. We study the Dihedral and Symmetric HSPs and how they relate to hard problems on lattices and graphs. Finally, we conclude with the known solutions and techniques, describe connections with efficient algorithms as well as miscellaneous variants of HSP. We also bring various contributions to the topic. We show that in theory, we can solve HSP over a given group inductively: the base case is solving HSP over its simple factor groups and the inductive step is building efficient oracles over a normal subgroup N and over the factor group G/N. We apply this analysis to the Dedekindian HSP to get an alternative abelian HSP algorithm based on a change of the underlying group. We also propose a quotient reduction by the normal group...
Subgroup Balancing Propensity Score
DONG, JING; Zhang, Junni L; Li, Fan
2017-01-01
We investigate the estimation of subgroup treatment effects with observational data. Existing propensity score matching and weighting methods are mostly developed for estimating overall treatment effect. Although the true propensity score should balance covariates for the subgroup populations, the estimated propensity score may not balance covariates for the subgroup samples. We propose the subgroup balancing propensity score (SBPS) method, which selects, for each subgroup, to use either the ...
Teemu Smura
Full Text Available Genetic recombination is considered to be a very frequent phenomenon among enteroviruses (Family Picornaviridae, Genus Enterovirus. However, the recombination patterns may differ between enterovirus species and between types within species. Enterovirus C (EV-C species contains 21 types. In the capsid coding P1 region, the types of EV-C species cluster further into three sub-groups (designated here as A-C. In this study, the recombination pattern of EV-C species sub-group B that contains types CVA-21, CVA-24, EV-C95, EV-C96 and EV-C99 was determined using partial 5'UTR and VP1 sequences of enterovirus strains isolated during poliovirus surveillance and previously published complete genome sequences. Several inter-typic recombination events were detected. Furthermore, the analyses suggested that inter-typic recombination events have occurred mainly within the distinct sub-groups of EV-C species. Only sporadic recombination events between EV-C species sub-group B and other EV-C sub-groups were detected. In addition, strict recombination barriers were inferred for CVA-21 genotype C and CVA-24 variant strains. These results suggest that the frequency of inter-typic recombinations, even within species, may depend on the phylogenetic position of the given viruses.
Smura, Teemu; Blomqvist, Soile; Vuorinen, Tytti; Ivanova, Olga; Samoilovich, Elena; Al-Hello, Haider; Savolainen-Kopra, Carita; Hovi, Tapani; Roivainen, Merja
2014-01-01
Genetic recombination is considered to be a very frequent phenomenon among enteroviruses (Family Picornaviridae, Genus Enterovirus). However, the recombination patterns may differ between enterovirus species and between types within species. Enterovirus C (EV-C) species contains 21 types. In the capsid coding P1 region, the types of EV-C species cluster further into three sub-groups (designated here as A–C). In this study, the recombination pattern of EV-C species sub-group B that contains types CVA-21, CVA-24, EV-C95, EV-C96 and EV-C99 was determined using partial 5′UTR and VP1 sequences of enterovirus strains isolated during poliovirus surveillance and previously published complete genome sequences. Several inter-typic recombination events were detected. Furthermore, the analyses suggested that inter-typic recombination events have occurred mainly within the distinct sub-groups of EV-C species. Only sporadic recombination events between EV-C species sub-group B and other EV-C sub-groups were detected. In addition, strict recombination barriers were inferred for CVA-21 genotype C and CVA-24 variant strains. These results suggest that the frequency of inter-typic recombinations, even within species, may depend on the phylogenetic position of the given viruses. PMID:24722726
On quantum algorithms for noncommutative hidden subgroups
Ettinger, M. [Los Alamos National Lab., NM (United States); Hoeyer, P. [Odense Univ. (Denmark)
1998-12-01
Quantum algorithms for factoring and discrete logarithm have previously been generalized to finding hidden subgroups of finite Abelian groups. This paper explores the possibility of extending this general viewpoint to finding hidden subgroups of noncommutative groups. The authors present a quantum algorithm for the special case of dihedral groups which determines the hidden subgroup in a linear number of calls to the input function. They also explore the difficulties of developing an algorithm to process the data to explicitly calculate a generating set for the subgroup. A general framework for the noncommutative hidden subgroup problem is discussed and they indicate future research directions.
Chaparro, Camila M; Dewey, Kathryn G
2010-01-01
The term 'lipid-based nutrient supplements' (LNS) refers generically to a range of fortified, lipid-based products, including products like Ready-to-Use Therapeutic Foods (RUTF) (a large daily ration with relatively low micronutrient concentration) as well as highly concentrated supplements (1-4 teaspoons/day, providing groups [e.g. infants and children between 6 and 24 months of age, and pregnant and lactating women (PLW)]. Currently, the main food and nutrition interventions in emergency settings include general food distribution (GFD) rations, which are provided to the affected population as a whole, and selective (or supplementary) feeding programs (SFP), which are to be provided to nutritionally vulnerable or malnourished individuals. In addition to logistical and operational challenges that may limit the intended effect of these programs, the nutritional quality of the food commodities provided may be insufficient to meet the needs of infants and young children and PLW. Because these subgroups have particularly high nutrient needs for growth and development, meeting these needs is challenging in settings where the ration is limited to a few food commodities, with little access to a diverse diet and bioavailable sources of micronutrients. In recent years, there has been increased attention to adding micronutrient interventions, on top of the other food-based interventions (such as GFDs and SFPs), to fill micronutrient gaps in diets in emergency settings. The focus of this document is the potential role of LNS in meeting the nutritional needs of these vulnerable subgroups, with the goal of preventing malnutrition in emergency-affected populations. The document addresses the desired nutritional formulation of LNS for these target groups, taking into account the expected bioavailability of relevant nutrients and toxicity concerns. It also discusses the recommended chemical forms of the fortificants in LNS; stability and shelf-life considerations; production
Anderson, John J; Fordham, Sarah; Overman, Lynne; Dignum, Helen; Wood, Katrina; Proctor, Stephen J; Crosier, Stephen; Angus, Brian; Culpin, Rachel E; Mainou-Fowler, Tryfonia
2009-11-01
Diffuse large B-cell lymphoma (DLBCL) forms a heterogeneous collection of aggressive non-Hodgkin's Lymphoma in which three principle classes of neoplasia have been defined according to gene expression and immunophenotyping studies. The present investigation sought to examine the immunophenotype of proposed subgroups and relate these to patient survival. A series of 155 DLBCL treated uniformly with anthracycline therapy in clinical trials, were stratified upon the basis of common biomarker expression with combination immunophenotype being related to patient overall survival. Stratification of tumours with respect to combined expression profiles of the three biological markers (CD10, Bcl-6 and MUM-1) revealed six groups showing significant differences in survival (p=0.014). The greatest difference resided between distinct populations of germinal centre (GC) cell tumours; the first being CD10-, Bcl-6+, MUM-1- and the second CD10+ Bcl-6+ MUM-1+ (p=0.002). The former group displayed median survival time of 143 months, the latter only 11 months. A third population of GC tumours (CD10+ Bcl-6+ and MUM-1-) also displayed a relative short median survival (32 months). Of the three groups presenting a non-GC or activated B cell (NGC/ABC) phenotype, only one (CD10-, Bcl-6+ and MUM-1+) presented short-term median survival (27 months) comparable with poor prognosis GC sub-populations. Within the remaining ABC tumour groups (CD10- Bcl-6- MUM-1- and CD10- Bcl-6- MUM-1+) patients presented intermediate median survival times of 54 and 58 months, respectively. Thus, the GC phenotype did not act as a universal indicator of good clinical prognosis, but rather multiple groups of GC tumours were associated with distinct overall survival profiles. Ultimately, the data allowed definition of a predictive algorithm defining three groups predicting poor, intermediate and good clinical prognosis. The first of these comprised two patient sub-populations with GC-like tumours together with one sub
Teemu Smura; Soile Blomqvist; Tytti Vuorinen; Olga Ivanova; Elena Samoilovich; Haider Al-Hello; Carita Savolainen-Kopra; Tapani Hovi; Merja Roivainen
2014-01-01
Genetic recombination is considered to be a very frequent phenomenon among enteroviruses (Family Picornaviridae, Genus Enterovirus). However, the recombination patterns may differ between enterovirus species and between types within species. Enterovirus C (EV-C) species contains 21 types. In the capsid coding P1 region, the types of EV-C species cluster further into three sub-groups (designated here as A-C). In this study, the recombination pattern of EV-C species sub-group B that contains ty...
Finite Nilpotent Groups with 5 Conjugacy Classes of Noncyclic Subgroups%非循环子群共轭类个数为5的有限幂零群
郭凯艳; 曹洪平; 陈贵云
2012-01-01
给出了非循环子群共轭类个数为5的有限幂零群的分类.由此,对非循环子群共轭类个数不大于5的有限幂零群进行了完全分类.%The finite nilpotent groups with 5 conjugacy classes of noncyclic subgroups are completely classified, from which one can give the structure of all finite nilpotent groups with the number of conjugacy classes of noncyclic subgroups at most 5.
Mikalsen, Stine Gyland; Jeppesen Edin, Nina; Sandvik, Joe Alexander; Pettersen, Erik Olai
2017-01-01
Background Previous studies have shown that combined treatment with internal ultra-low dose-rate irradiation selectively inactivated hypoxic T-47D breast cancer cells after three to five weeks of treatment. However, 2-3% of the hypoxic cells were found to survive and restart proliferation upon re-oxygenation. Purpose To investigate the metastatic potential and characteristics of radiosensitivity of these surviving cells, named T - 47 DS. Material and Methods The T - 47 DS cells were grown in ambient air without irradiation. A cloning experiment identified two sub-groups with different DNA content ([Formula: see text] and [Formula: see text]). Furthermore, radiosensitivity and presence of hyper-radiosensitivity (HRS) was measured by Co-60 challenge irradiation and relative migration was determined by scratch assays. Results The two subpopulations of T - 47 DS had different DNA content; one had abnormally high DNA content ([Formula: see text]) and one had DNA content similar to wild-type T-47D cells ([Formula: see text]). HRS was surprisingly present in cells of the cloned population [Formula: see text], but was absent in cells of both [Formula: see text] and T - 47 DS. The radio response of T - 47 DS, [Formula: see text] at higher radiation doses were similar to that of T-47D cells, and neither subpopulation showed increased migration compared with wild-type T-47D. Conclusion No increase in the risk of metastasis was found and only slight changes in radiosensitivity in response to conventional clinical doses was observed. Thus, the data suggest that if ultra-low dose-rate irradiation is used for targeting the hypoxic tumor fraction, conventional high dose-rate irradiation can be used to eradicate eventual surviving cells as well as cells in the well oxygenated areas of the tumor.
Yamazaki, Hiroyoshi; Kobayashi, Noriko; Taketsuna, Masanori; Tajima, Koyuki; Suzuki, Nahoko; Murakami, Masahiro
2017-07-20
To evaluate the long-term safety and effectiveness of tadalafil in pediatric patients with pulmonary arterial hypertension (PAH) in real-world clinical practice. This is an observational surveillance of PAH patients receiving tadalafil in the contracted sites. A sub-group analysis was performed of 391 pediatric PAH patients (events (AEs), and serious adverse drug reactions (SADRs). Effectiveness measurements included change in World Health Organization (WHO) functional classification of PAH, cardiac catheterization (pulmonary arterial pressure: PAP), and echocardiography (tricuspid regurgitation pressure gradient: TRPG). Survival rate was also measured. The mean patient age was 5.7 ± 5.34 years. Associated PAH (APAH) and idiopathic PAH (IPAH) accounted for 76.0% and 17.6%, respectively, of the PAH patients. Patients were followed for up to 2 years. Among 391 patients analyzed for safety, the overall incidence rate of ADRs was 16.6%. The common ADRs (≥ 1%) were headache (2.8%), hepatic function abnormal, platelet count decreased (1.3% each), and epistaxis, (1.0%). Eleven patients (2.8%) reported 16 SADRs. Three patients died secondary to SADRs. For the effectiveness analysis, the incidence of WHO functional class improvement at 3 months, 1 year, and 2 years after the initiation of tadalafil and last observation in pediatric patients were 16.5%, 19.7%, and 16.3%, respectively. Both PAP and TRPG showed a statistically significant reduction at last observation. This manuscript reveals the use of tadalafil in the real-world pediatric population with an acceptable safety profile in Japan.
Monath, Thomas P; Vasconcelos, Pedro F C
2015-03-01
Yellow fever, a mosquito-borne flavivirus disease occurs in tropical areas of South America and Africa. It is a disease of major historical importance, but remains a threat to travelers to and residents of endemic areas despite the availability of an effective vaccine for nearly 70 years. An important aspect is the receptivity of many non-endemic areas to introduction and spread of yellow fever. This paper reviews the clinical aspects, pathogenesis, and epidemiology of yellow fever, with an emphasis on recent changes in the distribution and incidence of the disease. Recent knowledge about yellow fever 17D vaccine mechanism of action and safety are discussed.
Mabry, Robert L; Frankfurt, Alan
2011-01-01
background: Optimal airway management protocols for the prehospital battlefield setting have not been defined. Airway management strategies in this environment must take into account the injury patterns, the environment and training requirements of military prehospital providers. This is a post-hoc, sub-group analysis of the Registry of Emergency Airways Arriving at Combat Hospitals or REACH database. This study examines only those patients who had advanced airways placed for trauma by an enlisted military medic at the point of injury. results: Twenty (100%) of the patients had a traumatic injury, 19 (95%) were male, and 13 (65%) had a gun shot wounds (GSWs) as the mechanism of injury. The majority, 12 (60%) patients had an esophageal-tracheal airway device placed. Of the remaining patients, four (20%) underwent endotracheal intubation, three (15%) had a surgical cricothyroidotomy performed, and one (5%) had a Laryngeal Mask Airway (LMA) placed. Seventeen (85%) of the twenty patients were dead on arrival or died shortly after arrival at the Combat Support Hospital (CSH). All of the patients that died had a Glasgow Coma Scale (GCS) of three upon arrival. The Glasgow Coma Scale provides a score in the range 3-15; patients with scores of 3-8 are usually said to be in a coma. Three patients in this group survived to transfer from the CSH. Two of the transfers were lost to follow up, one with a GSW to the head and GCS of three, the other with a GCS of five from injuries sustained in an explosion. The third patient had a surgical cricothyroidotomy (SC) performed in the field for an expanding neck hematoma and recovered fully following surgery. conclusions: Casualties that tolerate invasive airway management without sedation in the context of trauma prognosticates a very high mortality. Airway management algorithms for military providers should reflect the casualties encountered on the battlefield not patients in cardiac arrest which predominate in the civilian EMS airway
D.R. Prince Williams
2015-09-01
Full Text Available Soft set theory plays a vital role in solving many complicated problems with inherited uncertainty. An n-ary algebraic systems is a generalization of algebraic structures and it is the most natural way for the further development, deeper understanding of their properties. In this paper, we apply soft set theory to an n-ary algebraic systems and introduce the notions of soft n-ary groups and soft n-ary subgroups. Further, some operations on soft sets are extended to the former. Finally, we provide the characterization of soft n-ary subgroups over an n-ary group (G,f and study their related properties.
Faryad Ali
2007-01-01
The Held group He discovered by Held [10] is a sporadic simple group of order 4030387200 = 210.3a.52.73.17. The group He has 11 conjugacy classes of maximal subgroups as determined by Butler [5] and listed in the ATLAS. Held himself determined much of the local structure of He as well as the conjugacy classes of its elements. Thompson calculated the character table of He. In the present paper, we determine the Fischer Clifford matrices and hence compute the character table of the non-split extension 3.S7,which is a maximal subgroups of He of index 226560 using the technique of Fischer-Clifford matrices. Most of the computations were carried out with the aid of the computer algebra system GAP.
M B Sai Prasad; Salvatore Siano
2010-12-01
Over the past few years there has been an increasing interest in researches related to the application of lasers in conservation, analysis and diagnostics of artwork surfaces. Among the many interesting problems to be tackled, one issue was drawing more interest because of the limitations it can impose on the use of lasers. Laser yellowing is a phenomenon wherein artwork surfaces assume a yellow hue when cleaned with Q-switched Nd:YAG (1064 nm) lasers in particular. Here the effect of yellowing has been studied and quantified for artwork surfaces (marble) using SFR Nd:YAG and LQS Nd:YAG lasers. Colorimetric measurements by employing a spectroradiometer helps to quantify the effect of yellowing by analysing three variables (chromaticity coordinates) of interest.
Combes, Robert; Balls, Michael
2007-03-01
A critical analysis is presented of the reports produced by four Technical Expert Working Group Sub-groups (SGs) on Ethical Review, Cost-Benefit, Authorisation and Scope, which were published on the EC website (http://ec.europa.eu/environment/chemicals/lab_animals/ia_info_en.htm), as part of the European Commission (EC)s review of EU Directive 86/609 EEC. This is in addition to our official response to the internet consultation questionnaire, submitted to the Commission on behalf of FRAME. Whilst the respective SG reports were extensive and detailed, we have identified several shortcomings, and in particular, a frequent lack of consensus among the SG members, resulting in a lack of clear guidance for the EC on what the revised Directive should contain, with reference to a number of crucial issues. Such indecisiveness could lead to wide discrepancies in the approaches of the EC, the European Parliament and the EU Member States concerning many issues of importance to animal welfare and the implementation of alternatives to animal experiments. These concerns range from logistical issues, such as requirements for named officers in authorised establishments, and the recording and publishing of statistics on animal use, to ethical and scientific problems, including the use of non-human primates, local ethical review, and education and training on the essential link between the Three Rs concept and best scientific practice. In each case, the basis for our concerns is explained, and suggestions for improvements to be incorporated into the revised Directive are made, in the hope that the harmonisation of approaches to laboratory animal experimentation and the use of alternative methods in the Member States can be maximised.
Talita Bernardon Mar
2013-12-01
Full Text Available Yellow dwarf disease, one of the most important diseases of cereal crops worldwide, is caused by virus species belonging to the Luteoviridae family. Forty-two virus isolates obtained from oat (Avena sativa L., wheat (Triticum aestivum L., barley (Hordeum vulgare L., corn (Zea mays L., and ryegrass (Lolium multiflorum Lam. collected between 2007 and 2008 from winter cereal crop regions in southern Brazil were screened by polymerase chain reaction (PCR with primers designed on ORF 3 (coat protein - CP for the presence of Barley yellow dwarf virus and Cereal yellow dwarf virus (B/CYDV. PCR products of expected size (~357 bp for subgroup II and (~831 bp for subgroup I were obtained for three and 39 samples, respectively. These products were cloned and sequenced. The subgroup II 3' partial CP amino acid deduced sequences were identified as BYDV-RMV (92 - 93 % of identity with "Illinois" Z14123 isolate. The complete CP amino acid deduced sequences of subgroup I isolates were confirmed as BYDV-PAV (94 - 99 % of identity and established a very homogeneous group (identity higher than 99 %. These results support the prevalence of BYDV-PAV in southern Brazil as previously diagnosed by Enzyme-Linked Immunosorbent Assay (ELISA and suggest that this population is very homogeneous. To our knowledge, this is the first report of BYDV-RMV in Brazil and the first genetic diversity study on B/CYDV in South America.
On Residual Separability of Subgroups in Split Extensions
A. A. Krjazheva
2015-01-01
Full Text Available In 1973, Allenby and Gregoras proved the following statement. Let G be a split extension of a ﬁnitely generated group A by the group B. 1 If in groups A and B all subgroups (all cyclic subgroups are ﬁnitely separable, then in group G all subgroups (all cyclic subgroups are ﬁnitely separable; 2 if in group A all subgroups are ﬁnitely separable, and in group B all ﬁnitely generated subgroups are ﬁnitely separable, then in group G all ﬁnitely generated subgroups are ﬁnitely separable. Recall that a group G is said to be a split extension of a group A by a group B, if the group A is a normal subgroup of G, B is a subgroup of G, G = AB and A ∩ B = 1. Recall also that the subgroup H of a group G is called ﬁnitely separable if for every element g of G, which does not belong to the subgroup H, there exists a homomorphism of G on a ﬁnite group in which the image of an element g does not belong to the image of the subgroup H. In this paper we obtained a generalization of the Allenby and Gregoras theorem by replacing the condition of the ﬁnitely generated group A by a more general one: for any natural number n the number of all subgroups of the group A of index n is ﬁnite. In fact, under this condition we managed to obtain a necessary and suﬃcient condition for ﬁnite separability of all subgroups (of all cyclic subgroups, of all ﬁnitely generated subgroups in the group G.
Hidden Subgroup States are Almost Orthogonal
Ettinger, M; Knill, E H; Ettinger, Mark; Hoyer, Peter; Knill, Emanuel
1999-01-01
It is well known that quantum computers can efficiently find a hidden subgroup $H$ of a finite Abelian group $G$. This implies that after only a polynomial (in $\\log |G|$) number of calls to the oracle function, the states corresponding to different candidate subgroups have exponentially small inner product. We show that this is true for noncommutative groups also. We present a quantum algorithm which identifies a hidden subgroup of an arbitrary finite group $G$ in only a linear (in $\\log |G|$) number of calls to the oracle function. This is exponentially better than the best classical algorithm. However our quantum algorithm requires an exponential amount of time, as in the classical case.
Prata Aluízio
2000-01-01
Full Text Available With the infestation by Aedes aegypti, urban yellow fever might already exist. This did not occur because of either the lacking of a sufficient contact between the diseased individual and the A. aegypti or perhaps because this, after sixty years without transmitting the virus, needs an adaptation phase to infecting again.
Subgroups Among Opiate Addicts
Berzins, Juris I.; And Others
1974-01-01
The principal objective of the present investigation was to delineate homogeneous MMPI profile subgroups (types) through multivariate clustering procedures and to compare the derived (replicable) types on measures of the components of "sociopathy" as well as on other psychometric devices. (Author)
Subgroups Among Opiate Addicts
Berzins, Juris I.; And Others
1974-01-01
The principal objective of the present investigation was to delineate homogeneous MMPI profile subgroups (types) through multivariate clustering procedures and to compare the derived (replicable) types on measures of the components of "sociopathy" as well as on other psychometric devices. (Author)
Semi Cover-avoidance Properties of Subgroups and Solvability of Finite Groups%子群的半覆盖-远离性与有限群的可解性
韦华全; 谷伟平; 黄杰山; 刘秀
2009-01-01
A subgroup H of a finite group G is said to have the semi cover-avoidance property in a group G if there is a chief series 1=G0
Wei YF
2015-09-01
Full Text Available Yu-Feng Wei,1 Ping-Hung Kuo,2 Ying-Huang Tsai,3 Chi-Wei Tao,4 Shih-Lung Cheng,5,13 Chao-Hsien Lee,6 Yao-Kuang Wu,7 Ning-Hung Chen,8 Wu-Huei Hsu,9 Jeng-Yuan Hsu,10 Ming-Shian Lin,11 Chin-Chou Wang12 1Department of Internal Medicine, E-Da Hospital/I-Shou University, Kaohsiung, Taiwan; 2Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; 3Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan; 4Department of Internal Medicine, Cheng-Hsin General Hospital, Taipei, Taiwan; 5Division of Thoracic Medicine, Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan; 6Division of Pulmonary and Critical Care Medicine, Mackay Memorial Hospital, Taipei, Taiwan; 7Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Tzu Chi Hospital, Taipei, Taiwan; 8Department of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan; 9Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University and China Medical University Hospital, Taichung, Taiwan; 10Division of Chest Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; 11Division of Pulmonary and Critical Care Medicine, Chia-Yi Christian Hospital, Chiayi, Taiwan; 12Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 13Department of Chemical Engineering and Materials Science, Yuan-Ze University, Taoyuan, Taiwan Background and objective: The overprescription of inhaled corticosteroids (ICS in the current Global Initiative for Chronic Obstructive Lung Disease (GOLD group A and B patients with chronic obstructive pulmonary disease (COPD is not uncommon in clinical practice. The aim of this study was to explore the factors associated with the use of ICS in these patients. Methods: The Taiwan obstructive lung disease (TOLD study was a
Crisp, John; Paris, Luis
2001-07-01
It was conjectured by Tits that the only relations amongst the squares of the standard generators of an Artin group are the obvious ones, namely that a^2 and b^2 commute if ab=ba appears as one of the Artin relations. In this paper we prove Tits' conjecture for all Artin groups. More generally, we show that, given a number m(s)>1 for each Artin generator s, the only relations amongst the powers s^m(s) of the generators are that a^m(a) and b^m(b) commute if ab=ba appears amongst the Artin relations.
Eriksen, N H; Hartzen, S H; Bangsborg, Jette Marie
1994-01-01
During the period 1961-91 a total of 567,635 strains of Staphylococcus aureus from hospitalized patients in Denmark have been characterized according to their antibiotic resistance, site of isolation and phage type. Strains of phage group II (typed by the phages 3A, 3C, 55 and 71) have been analy...
王海珍; 邱林丹; 王香儿
2016-01-01
Group disruptions are very prevalent in practice,yet only little research examines them. We extend the literature on group disruptions by exploring their antecedents and consequents. We propose both perception of guanxi(a Chinese indige⁃nous variable)and perceived organizational politics(an external environmental factor)play a role in group disruptions phe⁃nomenon,suggest that group members with high-level perception of guanxi are apt to form subgroups,and so are those who perceive high-level organizational politics. We further prove the importance of subgroup formations by extending the positive effects of subgroup formation on perceived group conflicts,including relationship,task and process conflict. We test our mod⁃el using 209 individuals from a Chinese group company. The analytical results strongly support our propositions.%在实践中团队分裂十分普遍，然而却少有研究关注这一现象。文章通过探究其前因和后果，扩展了团队分裂的相关研究。一方面，文章提出关系感知（中国本土变量）和组织政治感知（外部环境因素）对团队分裂现象的影响，即高水平关系感知或高水平组织政治感知的团队成员更趋于形成子群。另一方面，建立子群形成与团队冲突（包括关系、任务和过程冲突）的正向关系，以证明子群形成是团队研究中不可忽视的现象。最后，通过来自中国本土公司209名员工数据检验了模型，数据分析结果支持了文章的观点。
Expert-Guided Subgroup Discovery: Methodology and Application
Gamberger, D; 10.1613/jair.1089
2011-01-01
This paper presents an approach to expert-guided subgroup discovery. The main step of the subgroup discovery process, the induction of subgroup descriptions, is performed by a heuristic beam search algorithm, using a novel parametrized definition of rule quality which is analyzed in detail. The other important steps of the proposed subgroup discovery process are the detection of statistically significant properties of selected subgroups and subgroup visualization: statistically significant properties are used to enrich the descriptions of induced subgroups, while the visualization shows subgroup properties in the form of distributions of the numbers of examples in the subgroups. The approach is illustrated by the results obtained for a medical problem of early detection of patient risk groups.
Schmid Ralf
2008-02-01
Full Text Available Abstract Background The Sperm-coating protein/Tpx-1/Ag5/PR-1/Sc7 (SCP/TAPS domain is found across phyla and is a major structural feature of insect allergens, mammalian sperm proteins and parasitic nematode secreted molecules. Proteins containing this domain are implicated in diverse biological activities and may be important for chronic host/parasite interactions. Results We report the first description of an SCP/TAPS gene family (Schistosoma mansoni venom allergen-like (SmVALs in the medically important Platyhelminthes (class Trematoda and describe individual members' phylogenetic relationships, genomic organization and life cycle expression profiles. Twenty-eight SmVALs with complete SCP/TAPS domains were identified and comparison of their predicted protein features and gene structures indicated the presence of two distinct sub-families (group 1 & group 2. Phylogenetic analysis demonstrated that this group 1/group 2 split is zoologically widespread as it exists across the metazoan sub-kingdom. Chromosomal localisation and PCR analysis, coupled to inspection of the current S. mansoni genomic assembly, revealed that many of the SmVAL genes are spatially linked throughout the genome. Quantitative lifecycle expression profiling demonstrated distinct SmVAL expression patterns, including transcripts specifically associated with lifestages involved in definitive host invasion, transcripts restricted to lifestages involved in the invasion of the intermediate host and transcripts ubiquitously expressed. Analysis of SmVAL6 transcript diversity demonstrated statistically significant, developmentally regulated, alternative splicing. Conclusion Our results highlight the existence of two distinct SCP/TAPS protein types within the Platyhelminthes and across taxa. The extensive lifecycle expression analysis indicates several SmVAL transcripts are upregulated in infective stages of the parasite, suggesting that these particular protein products may be linked
Subgroup analysis in burnout : Relations between fatigue, anxiety, and depression.
van Dam, A.
2016-01-01
Several authors have suggested that burned out patients do not form a homogeneous group and that subgroups should be considered. The identification of these subgroups may contribute to a better understanding of the burnout construct and lead to more specific therapeutic interventions. Subgroup
海进科; 李正兴
2012-01-01
Mazur conjectured that the normalizer property holds for finite groups with abelian Sylow 2-subgroups.Let G be a finite group and let N be a normal subgroup of G such that Z（G/N） has only trivial units.In this paper,a connection is established between the automorphisms of G induced by units in Z（G/N） and Coleman automorphisms of N.Based on this connection,we confirm that if G is a finite group with abelian Sylow 2-subgroups and Z（G/F^＊（G）） has only trivial units then Mazur＇s conjecture holds for G.%Mazur猜想：具有阿贝尔Sylow 2-子群的有限群有正规化子性质.设G是一个有限群,N是G的一个正规子群且Z（G/N）仅有平凡单位,本文建立了由Z（G/N）中单位诱导的G的自同构与N的Coleman自同构之间的联系,在此基础上证明了若G是一个具有阿贝尔Sylow 2-子群的有限群且Z（G/F^＊（G））仅有平凡单位,则Mazur猜想对G成立.
Schreuder, D.A.
1978-01-01
The question is posed whether the application of a colour difference for the central line on the road is the best solution available for the coding of the categories of road. It has been proposed to apply yellow centre lines on roads with two-way traffic and white centre lines on roads with one-wa
Interpretation of Subgroup Effects in Published Trials
Hancock, Mark J; Kjær, Per; Korsholm, Lars;
2013-01-01
that report on treatment effect modifiers (subgroups) for specific physical therapy interventions. The key messages are: (1) point estimates of treatment modifier effect size (interaction effect) and their confidence intervals can be calculated using group-level data when individual patient-level data...
Attention Deficit Disorder (ADDH) and Delinquency Subgroups
J Gordon Millichap
1988-01-01
Two subgroups of hyperactive children (25 non-delinquent and 9 delinquent) and 1 group of 34 non-delinquent normal children were evaluated from childhood to adolescence at the National Center for Hyperactive Children, Encino, CA, using auditory evoked response potential (AERP) measures and EEG recordings.
Mishra, Trinath; Hoffmann, Rolf-Dieter; Schwickert, Christian; Poettgen, Rainer [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie
2011-08-15
The hexagonal Laves phase Ce{sub 2}RuAl{sub 3} ({identical_to} CeRu{sub 0.5}Al{sub 1.5}) was synthesized by high-frequence-melting of the elements in a sealed tantalum tube and subsequent annealing. The structure was refined from single-crystal X-ray diffraction data: MgZn{sub 2} type, P6{sub 3}/mmc, Z = 2, a = 565.38(9), c = 888.3(1) pm, wR2 = 0.0231, 193 F{sup 2} values and 13 parameters. The 2a (0.824 Ru + 0.176 Al) and 6h (0.956 Al + 0.044 Ru) Wyckoff positions show mixed occupancies leading to the composition CeRu{sub 0.48}Al{sub 1.52} for the investigated crystal. The aluminum atoms build up Kagome networks at z = 1/4 and z = 3/4 which are connected to a three-dimensional network by the ruthenium atoms. The cerium atoms fill cavities of coordination number 16 (3 Ru + 9 Al + 4 Ce) within the [RuAl{sub 3}] network. The Ce{sub 2}RuAl{sub 3} sample orders ferromagnetically at T{sub C} = 8.0(1) K. The cerium-rich aluminide Ce{sub 5}Ru{sub 3}Al{sub 2} shows unusually short Ce-Ru distances of 253 and 260 pm for the Ce1 position as a result of intermediate cerium valence. The structural distortions are discussed on the basis of a group-subgroup scheme for Pr{sub 5}Ru{sub 3}Al{sub 2} (space group I2{sub 1}3) and the superstructure variant Ce{sub 5}Ru{sub 3}Al{sub 2} (space group R3). (orig.)
主理想环上子群Gr在线性群中的扩群%Extended Group of the Subgroup Gr in Linear Group Over the Principal Ideal Ring
卫宗礼; 曲贺梅
2008-01-01
Suppose R is a principal ideal ring.R* is a multiplicative group which is composed of all reversible elements in R,and Mn(R),GL(n,R),SL(n,R)are denoted by,R*),SL(n,R)={g∈GL(n,R)|detg=1),SL(n,R)≤G≤GL(n,R)(n≥3),respectively,then basing on these facts,this paper mainly focus on discussing all extended groups of Gr={(AB OD)∈G|A∈GL(r,R),(1≤r＜n)}in G when R is a principal ideal ring.
Teemu Smura
Full Text Available Genus Enterovirus (Family Picornaviridae, consists of twelve species divided into genetically diverse types by their capsid protein VP1 coding sequences. Each enterovirus type can further be divided into intra-typic sub-clusters (genotypes. The aim of this study was to elucidate what leads to the emergence of novel enterovirus clades (types and genotypes. An evolutionary analysis was conducted for a sub-group of Enterovirus C species that contains types Coxsackievirus A21 (CVA-21, CVA-24, Enterovirus C95 (EV-C95, EV-C96 and EV-C99. VP1 gene datasets were collected and analysed to infer the phylogeny, rate of evolution, nucleotide and amino acid substitution patterns and signs of selection. In VP1 coding gene, high intra-typic sequence diversities and robust grouping into distinct genotypes within each type were detected. Within each type the majority of nucleotide substitutions were synonymous and the non-synonymous substitutions tended to cluster in distinct highly polymorphic sites. Signs of positive selection were detected in some of these highly polymorphic sites, while strong negative selection was indicated in most of the codons. Despite robust clustering to intra-typic genotypes, only few genotype-specific 'signature' amino acids were detected. In contrast, when different enterovirus types were compared, there was a clear tendency towards fixation of type-specific 'signature' amino acids. The results suggest that permanent fixation of type-specific amino acids is a hallmark associated with evolution of different enterovirus types, whereas neutral evolution and/or (frequency-dependent positive selection in few highly polymorphic amino acid sites are the dominant forms of evolution when strains within an enterovirus type are compared.
Smura, Teemu; Blomqvist, Soile; Vuorinen, Tytti; Ivanova, Olga; Samoilovich, Elena; Al-Hello, Haider; Savolainen-Kopra, Carita; Hovi, Tapani; Roivainen, Merja
2014-01-01
Genus Enterovirus (Family Picornaviridae,) consists of twelve species divided into genetically diverse types by their capsid protein VP1 coding sequences. Each enterovirus type can further be divided into intra-typic sub-clusters (genotypes). The aim of this study was to elucidate what leads to the emergence of novel enterovirus clades (types and genotypes). An evolutionary analysis was conducted for a sub-group of Enterovirus C species that contains types Coxsackievirus A21 (CVA-21), CVA-24, Enterovirus C95 (EV-C95), EV-C96 and EV-C99. VP1 gene datasets were collected and analysed to infer the phylogeny, rate of evolution, nucleotide and amino acid substitution patterns and signs of selection. In VP1 coding gene, high intra-typic sequence diversities and robust grouping into distinct genotypes within each type were detected. Within each type the majority of nucleotide substitutions were synonymous and the non-synonymous substitutions tended to cluster in distinct highly polymorphic sites. Signs of positive selection were detected in some of these highly polymorphic sites, while strong negative selection was indicated in most of the codons. Despite robust clustering to intra-typic genotypes, only few genotype-specific ‘signature’ amino acids were detected. In contrast, when different enterovirus types were compared, there was a clear tendency towards fixation of type-specific ‘signature’ amino acids. The results suggest that permanent fixation of type-specific amino acids is a hallmark associated with evolution of different enterovirus types, whereas neutral evolution and/or (frequency-dependent) positive selection in few highly polymorphic amino acid sites are the dominant forms of evolution when strains within an enterovirus type are compared. PMID:24695547
李育; 金红; 陈秉宇
2010-01-01
Objective Bw subgroup of ABO blood group system was investigated to reveal its molecular genetic basis in Chinese Han population.Methods The Abw subgroup of three relatives were identified by standard blood group serological techniques.The enhancer,promoter and exon 1 to exon 7including flanking intron sequences of ABO gene were amplified by polymerase chain reaction.Direct sequencing was then performed on the gel-purified PCR products.Afterwards the exon 7 with polymorphic sites were cloned into pcDNA3.1(-)vector and transformed into DH5α to carry out a haploid analysis.Results According to the direct sequencing analysis,sequence characteristics of the 3 tested subjects were found specific to partial sequence of A102,B101 and O02 alleles,thought the genotypes could not be confirmed directly.The haploid analysis affirmed that one allele is A102 while the other is a B101-O02 hybrid,which harbored 646T>A,657T>C and 681G>A variants compared with B101 allele.This hybrid allele was not detected in a 110 randomly selected samples.Conclusion The B101-O02 hybrid allele may account for the Bw phenotype and its molecular genetic basis.%目的 研究中国汉族个体红细胞ABO血型Bw亚型的分子遗传背景.方法 通过标准血型血清学方法 鉴定了1个家庭3例ABw亚型,PCR扩增样本基因组DNA的ABO基因增强子、启动子和外显子1～7及侧翼内含子序列,PCR产物经割胶纯化后直接测序,并将含有多态性位点的外显子7克隆到pcDNA3.1(-)质粒,转化DH5α后进行单倍体序列分析.结果 3例ABw亚型的直接序列分析发现其ABO基因均有A102、B101和002等3种等位基因部分序列特征,但无法直接确定其基因型.单倍体序列分析表明,其中1个等位基因为A102,另1个为B101-O02杂交等位基因,表现为B101等位基因基础上的646T>A,657T>C和681G>A变异.在110份随机样本中未发现该杂交等位基因.结论 B101和O02等位基因杂交可能是导致该Bw亚型的分子机制.
The ergodic theory of lattice subgroups
Gorodnik, Alexander
2010-01-01
The results established in this book constitute a new departure in ergodic theory and a significant expansion of its scope. Traditional ergodic theorems focused on amenable groups, and relied on the existence of an asymptotically invariant sequence in the group, the resulting maximal inequalities based on covering arguments, and the transference principle. Here, Alexander Gorodnik and Amos Nevo develop a systematic general approach to the proof of ergodic theorems for a large class of non-amenable locally compact groups and their lattice subgroups. Simple general conditions on the spectral theory of the group and the regularity of the averaging sets are formulated, which suffice to guarantee convergence to the ergodic mean
Beltoft, Vibe Meister; Binderup, Mona-Lise; Frandsen, Henrik Lauritz;
remains with respect to genotoxicity for the substances of this subgroup and their three representative substances. The Panel confirms, the need for an in vivo Comet assay performed in duodenum and liver for hex-2(trans)-enal [FL-no: 05.073]. For the two other representative substances of subgroup 1.......1.1 (nona-2(trans),6(cis)-dienal [FL-no: 05.058] and oct-2-enal [FL-no: 05.060]), a combined in vivo Comet assay and micronucleus assay would be required. For the latter, evidence of bone marrow exposure should be provided....
On an equivalence of fuzzy subgroups III
V. Murali
2003-01-01
Full Text Available This paper is the third in a series of papers studying equivalence classes of fuzzy subgroups of a given group under a suitable equivalence relation. We introduce the notion of a pinned flag in order to study the operations sum, intersection and union, and their behavior with respect to the equivalence. Further, we investigate the extent to which a homomorphism preserves the equivalence. Whenever the equivalences are not preserved, we have provided suitable counterexamples.
Beltoft, Vibe Meister; Binderup, Mona-Lise; Lund, Pia;
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 24 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group Evaluation 212, Revision 2. The Panel concluded in ...
On (F)s-Quasinormality of 2-Maximal Subgroups
Yufeng LIU; Xiaolong YU; Lijun HUO
2013-01-01
Let (F) be a class of finite groups.A subgroup H of a finite group G is said to be (F)s-quasinormal in G if there exists a normal subgroup T of G such that HT is s-permutable in G and (H ∩ T)HG/HG is contained in the (F)-hypercenter Z(F)∞(G/HG) of G/HG.In this paper,we use (F)s-quasinormal subgroups to study the structure of finite groups.Some new results are obtained.
Genetic markers for schizophrenic subgroups.
Lange, V
1982-01-01
By the study of hereditary serum protein markers in psychotic patients and normal controls, a surplus of Gc 1-1 (p less than 0.01) and transferrin B variants (p less than 0.0027) has been established in schizophrenias. Affective psychoses are characterized by an excess of the haptoglobin (Hp) serum type 2-2 (p less than 0.001). These general statements have to be modified in regard to the clinical and psychopathological subdivision beyond the traditional classification into two major groups of endogenous mental disease. Using Leonhard's criteria, the prevalence of Gc 1-1 is restricted to the systematic schizophrenias reaching its highest value in hebephrenias, which are followed by paraphrenic and catatonic forms in this trait. In contrast to this, periodical catatonia and affective paraphrenia, classified as subgroups of the unsystematic schizophrenias, have Gc 1-1 frequencies like healthy controls. On the other hand, the Hp 2-2 value is not increased in the systematic schizophrenias, but it displays a relative overplus in the unsystematic forms. Concerning the Hp 2-2 and Gc 1-1 frequencies a certain similarity can be observed between affective paraphrenia and the paranoid psychoses with late onset, it they are characterized by a cyclic axis syndrome as described by the Vienna school. The cycloid psychoses are marked by an extreme surplus of Hp 2-2 (p less than 0.001) and an overweight of Gc 1-1 (p less than 0.05). Probably the Gc and Hp alleles play a role as risk factors or accidental effectors in the multifactorial genetic systems responsible for the biological background of psychoses. For both serum systems a selective interaction is discussed considering the vitamin D transport by the Gc proteins with the relation to neuronal consolidation and the possible influence of Hp 2-2 on transport and receptor functions.
Aedes (Stegomyia) Corneti, A New Species of the Africanus Subgroup (Diptera: Culicidae)
1986-10-14
monkey to man in Bwamba County (Haddow, 1945; Haddow et al., 1947; Lumsden, 195 1; Haddow, 1968). In eastern Africa, at least four arboviruses have...subgroup are involved in the enzootic-epizootic cycles of yellow fever in primates in West and Central Africa (Germain, Sureau et al., 1976; Comet in
MPACT Subgroup Self-Shielding Efficiency Improvements
Stimpson, Shane [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Liu, Yuxuan [Univ. of Michigan, Ann Arbor, MI (United States); Collins, Benjamin S. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Clarno, Kevin T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
2016-08-31
Recent developments to improve the efficiency of the MOC solvers in MPACT have yielded effective kernels that loop over several energy groups at once, rather that looping over one group at a time. These kernels have produced roughly a 2x speedup on the MOC sweeping time during eigenvalue calculation. However, the self-shielding subgroup calculation had not been reevaluated to take advantage of these new kernels, which typically requires substantial solve time. The improvements covered in this report start by integrating the multigroup kernel concepts into the subgroup calculation, which are then used as the basis for further extensions. The next improvement that is covered is what is currently being termed as “Lumped Parameter MOC”. Because the subgroup calculation is a purely fixed source problem and multiple sweeps are performed only to update the boundary angular fluxes, the sweep procedure can be condensed to allow for the instantaneous propagation of the flux across a spatial domain, without the need to sweep along all segments in a ray. Once the boundary angular fluxes are considered to be converged, an additional sweep that will tally the scalar flux is completed. The last improvement that is investigated is the possible reduction of the number of azimuthal angles per octant in the shielding sweep. Typically 16 azimuthal angles per octant are used for self-shielding and eigenvalue calculations, but it is possible that the self-shielding sweeps are less sensitive to the number of angles than the full eigenvalue calculation.
Molecular identification of Candidatus Phytoplasma spp. associated with Sophora yellow stunt in Iran
Allahverdi Touhid
2017-06-01
Full Text Available In the spring of 2012, sophora (Sophora alopecuroides L. plants showing symptoms of leaf yellowing, little leaves and stunting were observed in Firooz-kuh (Tehran province, Sari (Mazandaran province and Urmia (West Azerbaijan province in Iran. Symptomatic plants from the three locations were subjected to nested polymerase chain reaction (PCR to amplify 16SrRNA using primer pair P1/P7 followed by primer pair R16F2n/R16R2. The amplicons were purified, sequenced and the nucleotide sequences were analyzed by virtual restriction fragment length polymorphism (RFLP. The phytoplasmas associated with the yellows disease were identified as members of the 16SrIX group (Candidatus Phytoplasma phoenicium and the 16SrXII group (Candidatus Phytoplasma solani. The two phytoplasmas were placed in 16SrIX-C and 16SrXII-A subgroups, respectively, in constructed phylogenetic trees. This is the first report on sophora yellows associated with Candidatus Phytoplasma phoenicium.
Dixit Ramakant
2007-01-01
Full Text Available A case of yellow nail syndrome is described in a forty year old male patient who presented with classical triad of this syndrome i.e. deformed yellow nails, lymph-edema and chronic recurrent pleural effusion. The practical problems in the di-agnosis are also briefly discussed with emphasis on awareness of this rare clinical entity.
Additive subgroups of topological vector spaces
Banaszczyk, Wojciech
1991-01-01
The Pontryagin-van Kampen duality theorem and the Bochner theorem on positive-definite functions are known to be true for certain abelian topological groups that are not locally compact. The book sets out to present in a systematic way the existing material. It is based on the original notion of a nuclear group, which includes LCA groups and nuclear locally convex spaces together with their additive subgroups, quotient groups and products. For (metrizable, complete) nuclear groups one obtains analogues of the Pontryagin duality theorem, of the Bochner theorem and of the Lévy-Steinitz theorem on rearrangement of series (an answer to an old question of S. Ulam). The book is written in the language of functional analysis. The methods used are taken mainly from geometry of numbers, geometry of Banach spaces and topological algebra. The reader is expected only to know the basics of functional analysis and abstract harmonic analysis.
Beltoft, Vibe Meister; Binderup, Mona-Lise; Lund, Pia
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of five flavouring substances from subgroup 3.3 of FGE.19. In the Flavouring Group Evaluation 216 (FGE.216) additional genotoxicity...... of animals treated with 2-phenylcrotonaldehyde. Moreover, since the substance was genotoxic only without metabolic activation, it appears necessary to prove the absence of genotoxic effect locally in the gastro intestinal system using the Comet assay....
Normal subgroup generated by a plane polynomial automorphism
Furter, Jean-Philippe
2009-01-01
We study the normal subgroup generated by a non trivial element f in the group G of complex plane polynomial automorphisms having Jacobian determinant 1. On one hand if f has length at most 8 relatively to the classical amalgamated product structure of G, we prove that = G. On the other hand if f is a sufficiently generic element of even length at least 14, we prove that is a proper subgroup of G.
Demonstration of Microbial Subgroups among Normal Vaginal Microbiota Data
Lee, M.-L. T.
2011-01-01
In this study we identified subgroups of observations relating to the healthy vaginal microbiota. This microbiota resides in a dynamic environment that undergoes cyclic change during the menstrual cycle. Cluster analysis procedures were applied to divide a set of 226 normal microbiota observations into groups. Three subgroups containing 100, 65, and 61 observations were identified. Plots of principal components determined by canonical analysis were obtained to demonstrate graphically the clus...
Hagborg, Winston J.
1996-01-01
Comparison of middle-school-age students with learning disabilities, grouped according to their self-reported ratings of scholastic competence, found significant differences between the low subgroup and the medium/high subgroups on internal locus of control for positive events, school attitudes, and global self-worth. Subgroups did not differ in…
Can the tinnitus spectrum identify tinnitus subgroups?
Karin M Heijneman
2013-01-01
Full Text Available The tinnitus spectrum is a psycho-acoustic metric of tinnitus. Previous work found a tight relation between the spectrum and the tone audiogram. This suggests that the spectrum and the audiogram provide essentially the same information, and the added value of the spectrum is limited. In order to test whether the spectrum shows tinnitus characteristics that cannot be inferred from the audiogram, we re-examined the relation between the tinnitus spectrum and the tone audiogram, in a group of 80 tinnitus patients. We defined three subgroups of patients, using the shape of their tinnitus spectrum: (1 patients with a spectrum, monotonously increasing with frequency (2 patients with a distinct peak in their spectrum, (3 all other patients. Patients in group 3 typically showed low frequency tinnitus spectra. In all three groups, the largest hearing loss was at high frequencies (>2 kHz. The mean audiograms of group 1 and 2 were remarkably similar; group 3 had an additional hearing loss for the lower frequencies (<2 kHz. The three groups did not differ with respect to age, sex, or tinnitus questionnaire outcomes. In subgroups 2 and 3, the shape of the spectrum clearly differed from that of the tone audiogram. In other words, the spectrum technique provided information that could not have been obtained by tone audiometry alone. Therefore, the spectrum measurement may develop into a technique that can differentiate between classes of tinnitus. This may eventually contribute to the effective management of tinnitus, as various classes of tinnitus may require different therapeutic interventions.
The impact of subgroup type and subgroup configurational properties on work team performance.
Carton, Andrew M; Cummings, Jonathon N
2013-09-01
Scholars have invoked subgroups in a number of theories related to teams, yet certain tensions in the literature remain unresolved. In this article, we address 2 of these tensions, both relating to how subgroups are configured in work teams: (a) whether teams perform better with a greater number of subgroups and (b) whether teams perform better when they have imbalanced subgroups (majorities and minorities are present) or balanced subgroups (subgroups are of equal size). We predict that the impact of the number and balance of subgroups depends on the type of subgroup-whether subgroups are formed according to social identity (i.e., identity-based subgroups) or information processing (i.e., knowledge-based subgroups). We first propose that teams are more adversely affected by 2 identity-based subgroups than by any other number, yet the uniquely negative impact of a 2-subgroup configuration is not apparent for knowledge-based subgroups. Instead, a larger number of knowledge-based subgroups is beneficial for performance, such that 2 subgroups is worse for performance when compared with 3 or more subgroups but better for performance when compared with no subgroups or 1 subgroup. Second, we argue that teams perform better when identity-based subgroups are imbalanced yet knowledge-based subgroups are balanced. We also suggest that there are interactive effects between the number and balance of subgroups-however, the nature of this interaction depends on the type of subgroup. To test these predictions, we developed and validated an algorithm that measures the configurational properties of subgroups in organizational work teams. Results of a field study of 326 work teams from a multinational organization support our predictions.
Subgroup finding via Bayesian additive regression trees.
Sivaganesan, Siva; Müller, Peter; Huang, Bin
2017-03-09
We provide a Bayesian decision theoretic approach to finding subgroups that have elevated treatment effects. Our approach separates the modeling of the response variable from the task of subgroup finding and allows a flexible modeling of the response variable irrespective of potential subgroups of interest. We use Bayesian additive regression trees to model the response variable and use a utility function defined in terms of a candidate subgroup and the predicted response for that subgroup. Subgroups are identified by maximizing the expected utility where the expectation is taken with respect to the posterior predictive distribution of the response, and the maximization is carried out over an a priori specified set of candidate subgroups. Our approach allows subgroups based on both quantitative and categorical covariates. We illustrate the approach using simulated data set study and a real data set. Copyright © 2017 John Wiley & Sons, Ltd.
Quantum Hidden Subgroup Problems A Mathematical Perspective
Lomonaco, S J; Lomonaco, Samuel J.; Kauffman, Louis H.
2002-01-01
The ultimate objective of this paper is to create a stepping stone to the development of new quantum algorithms. The strategy chosen is to begin by focusing on the class of abelian quantum hidden subgroup algorithms, i.e., the class of abelian algorithms of the Shor/Simon genre. Our strategy is to make this class of algorithms as mathematically transparent as possible. By the phrase "mathematically transparent" we mean to expose, to bring to the surface, and to make explicit the concealed mathematical structures that are inherently and fundamentally a part of such algorithms. In so doing, we create symbolic abelian quantum hidden subgroup algorithms that are analogous to the those symbolic algorithms found within such software packages as Axiom, Cayley, Maple, Mathematica, and Magma. As a spin-off of this effort, we create three different generalizations of Shor's quantum factoring algorithm to free abelian groups of finite rank. We refer to these algorithms as wandering (or vintage Z_Q) Shor algorithms. They...
Research methods for subgrouping low back pain
Kent, Peter; Keating, Jennifer L; Leboeuf-Yde, Charlotte
2010-01-01
important distinctions in their treatment needs or prognoses. Due to a proliferation of research methods and variability in how subgrouping results are interpreted, it is timely to open discussion regarding a conceptual framework for the research designs and statistical methods available for subgrouping...... studies (a method framework). The aims of this debate article are: (1) to present a method framework to inform the design and evaluation of subgrouping research in low back pain, (2) to describe method options when investigating prognostic effects or subgroup treatment effects, and (3) to discuss...... the strengths and limitations of research methods suitable for the hypothesis-setting phase of subgroup studies....
Identities on Maximal Subgroups of GLn(D)
D. Kiani; M. Mahdavi-Hezavehi
2005-01-01
Let D be a division ring with centre F. Assume that M is a maximal subgroup of GLn(D) (n ≥ 1) such that Z(M) is algebraic over F. Group identities on M and polynomial identities on the F-linear hull F[M] are investigated. It is shown that if F[M]is a PI-algebra, then [D: F] ＜∞. When D is non-commutative and F is infinite, it is also proved that if M satisfies a group identity and F[M] is algebraic over F, then we have either M = K* where K is a field and [D: F] ＜∞, or M is absolutely irreducible. For a finite dimensional division algebra D, assume that N is a subnormal subgroup of GLn(D)and M is a maximal subgroup of N. If M satisfies a group identity, it is shown that M is abelian-by-finite.
Theodoridou, Katerina; Zhang, Xuewei; Vail, Sally; Yu, Peiqiang
2015-06-10
Recently, new lines of yellow-seeded (CS-Y) and black-seeded canola (CS-B) have been developed with chemical and structural alteration through modern breeding technology. However, no systematic study was found on the bioactive compounds, chemical functional groups, fatty acid profiles, inherent structure, nutrient degradation and absorption, or metabolic characteristics between the newly developed yellow- and black-seeded canola lines. This study aimed to systematically characterize chemical, structural, and nutritional features in these canola lines. The parameters accessed include bioactive compounds and antinutrition factors, chemical functional groups, detailed chemical and nutrient profiles, energy value, nutrient fractions, protein structure, degradation kinetics, intestinal digestion, true intestinal protein supply, and feed milk value. The results showed that the CS-Y line was lower (P ≤ 0.05) in neutral detergent fiber (122 vs 154 g/kg DM), acid detergent fiber (61 vs 99 g/kg DM), lignin (58 vs 77 g/kg DM), nonprotein nitrogen (56 vs 68 g/kg DM), and acid detergent insoluble protein (11 vs 35 g/kg DM) than the CS-B line. There was no difference in fatty acid profiles except C20:1 eicosenoic acid content (omega-9) which was in lower in the CS-Y line (P compounds differed (P bioactive compounds, total polyphenols tended to be different (6.3 vs 7.2 g/kg DM), but there were no differences in erucic acid and condensed tannins with averages of 0.3 and 3.1 g/kg DM, respectively. When protein was portioned into five subfractions, significant differences were found in PA, PB1 (65 vs 79 g/kg CP), PB2, and PC fractions (10 vs 33 g/kg CP), indicating protein degradation and supply to small intestine differed between two new lines. In terms of protein structure spectral profile, there were no significant differences in functional groups of amides I and II, α helix, and β-sheet structure as well as their ratio between the two new lines, indicating no difference in
Subgroup Analysis in Burnout: Relations Between Fatigue, Anxiety, and Depression
van Dam, Arno
2016-01-01
Several authors have suggested that burned out patients do not form a homogeneous group and that subgroups should be considered. The identification of these subgroups may contribute to a better understanding of the burnout construct and lead to more specific therapeutic interventions. Subgroup analysis may also help clarify whether burnout is a distinct entity and whether subgroups of burnout overlap with other disorders such as depression and chronic fatigue syndrome. In a group of 113 clinically diagnosed burned out patients, levels of fatigue, depression, and anxiety were assessed. In order to identify possible subgroups, we performed a two-step cluster analysis. The analysis revealed two clusters that differed from one another in terms of symptom severity on the three aforementioned measures. Depression appeared to be the strongest predictor of group membership. These results are considered in the light of the scientific debate on whether burnout can be distinguished from depression and whether burnout subtyping is useful. Finally, implications for clinical practice and future research are discussed. PMID:26869983
Subgroup analysis in burnout: relations between fatigue, anxiety and depression
Arno eVan Dam
2016-02-01
Full Text Available Several authors have suggested that burned out patients do not form a homogeneous group and that subgroups should be considered. The identification of these subgroups may contribute to a better understanding of the burnout construct and lead to more specific therapeutic interventions. Subgroup analysis may also help clarify whether burnout is a distinct entity and whether subgroups of burnout overlap with other disorders such as depression and chronic fatigue syndrome. In a group of 113 clinically-diagnosed burned out patients, levels of fatigue, depression and anxiety were assessed. In order to identify possible subgroups, we performed a two-step cluster analysis. The analysis revealed two clusters that differed from one another in terms of symptom severity on the three aforementioned measures. Depression appeared to be the strongest predictor of group membership. These results are considered in the light of the scientific debate on whether burnout can be distinguished from depression and whether burnout subtyping is useful. Finally, implications for clinical practice and future research are discussed.
Evaluation of lymphocyte subgroups in children with subacute sclerosing panencephalitis.
Yilmaz, C; Yuca, S A; Yilmaz, N; Oner, A F; Caksen, H
2009-01-01
The aetiology of subacute sclerosing panencephalitis (SSPE) remains to be fully elucidated, although it follows infection with a hypermutant defective M-protein measles virus. This study analysed peripheral blood lymphocyte subgroups to determine their role in the pathophysiology of SSPE. It included 22 children with SSPE aged 2 - 15 years (patient group) and 22 age- and gender-matched healthy children (control group). In children or= 6 years old, there were no significant differences in the lymphocyte subgroups. In conclusion, these findings suggest that a low CD4(+) lymphocyte count might be responsible for SSPE in younger children.
Mølgaard Nielsen, Anne; Hestbaek, Lise; Vach, Werner
2017-01-01
. Previously, we developed two novel suggestions for subgrouping patients with low back pain based on Latent Class Analysis of patient baseline characteristics (patient history and physical examination), which resulted in 7 subgroups when using a single-stage analysis, and 9 subgroups when using a two...... associated with these outcomes, and (iii) assessed the performance of the novel subgroupings as compared to the following variables: two existing subgrouping tools (STarT Back Tool and Quebec Task Force classification), four baseline characteristics and a group of previously identified domain...
Clinical Subgroups in Bilateral Meniere Disease
Frejo, Lidia; Soto-Varela, Andres; Santos-Perez, Sofía; Aran, Ismael; Batuecas-Caletrio, Angel; Perez-Guillen, Vanesa; Perez-Garrigues, Herminio; Fraile, Jesus; Martin-Sanz, Eduardo; Tapia, Maria C.; Trinidad, Gabriel; García-Arumi, Ana María; González-Aguado, Rocío; Espinosa-Sanchez, Juan M.; Marques, Pedro; Perez, Paz; Benitez, Jesus; Lopez-Escamez, Jose A.
2016-01-01
Meniere disease (MD) is a heterogeneous clinical condition characterized by sensorineural hearing loss, episodic vestibular symptoms, and tinnitus associated with several comorbidities, such as migraine or autoimmune disorders (AD). The frequency of bilateral involvement may range from 5 to 50%, and it depends on the duration of the disease. We have performed a two-step cluster analysis in 398 patients with bilateral MD (BMD) to identify the best predictors to define clinical subgroups with a potential different etiology to improve the phenotyping of BMD and to develop new treatments. We have defined five clinical variants in BMD. Group 1 is the most frequently found, includes 46% of patients, and is defined by metachronic hearing loss without migraine and without AD. Group 2 is found in 17% of patients, and it is defined by synchronic hearing loss without migraine or AD. Group 3, with 13% of patients, is characterized by familial MD, while group 4, that includes 12% of patients, is associated by the presence of migraine in all cases. Group 5 is found in 11% of patients and is defined by AD. This approach can be helpful in selecting patients for genetic and clinical research. However, further studies will be required to improve the phenotyping in these clinical variants for a better understanding of the diverse etiological factors contributing to BMD. PMID:27822199
Clinical subgroups in bilateral Meniere disease
Lidia Frejo
2016-10-01
Full Text Available Meniere disease (MD is a heterogeneous clinical condition characterized by sensorineural hearing loss, episodic vestibular symptoms and tinnitus associated with several comorbidities such as migraine or autoimmune disorders (AD. The frequency of bilateral involvement may range from 5-50% and it depends on the duration of the disease. We have performed a two-step cluster analysis in 398 patients with bilateral MD to identify the best predictors to define clinical subgroups with a potential different etiology to improve the phenotyping of bilateral MD and to develop new treatments. We have defined five clinical variants in bilateral MD. Group 1 is the most frequently found, includes 46% of patients, and is defined by metachronic hearing loss without migraine and without AD. Group 2 is found in 17% of patients, and it is defined by synchronic hearing loss without migraine or AD. Group 3, with 13% of patients, is characterized by familial MD, while group 4, that includes 12% of patients, is associated by the presence of migraine in all cases. Group 5 is found in 11% of patients and is defined by AD. This approach can be helpful in selecting patients for genetic and clinical research. However, further studies will be required to improve the phenotyping in these clinical variants for a better understanding of the diverse etiological factors contributing to bilateral MD.
Factor analysis identifies subgroups of constipation
Philip G Dinning; Mike Jones; Linda Hunt; Sergio E Fuentealba; Jamshid Kalanter; Denis W King; David Z Lubowski; Nicholas J Talley; Ian J Cook
2011-01-01
AIM: To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction. METHODS: One hundred and ninety-one patients presenting to a Gastroenterology clinic with constipation and 32 constipated patients responding to a newspaper advertisement completed a 53-item, wide-ranging selfreport questionnaire. One hundred of these patients had colonic transit measured scintigraphically. Factor analysis determined whether constipation-related symptoms grouped into distinct aspects of symptomatology. Cluster analysis was used to determine whether individual patients naturally group into distinct subtypes. RESULTS: Cluster analysis yielded a 4 cluster solution with the presence or absence of pain and laxative unresponsiveness providing the main descriptors. Amongst all clusters there was a considerable proportion of patients with demonstrable delayed colon transit, irritable bowel syndrome positive criteria and regular stool frequency. The majority of patients with these characteristics also reported regular laxative use. CONCLUSION: Factor analysis identified four constipation subgroups, based on severity and laxative unresponsiveness, in a constipated population. However, clear stratification into clinically identifiable groups remains imprecise.
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF
2014-04-01
Full Text Available The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of flavouring substances from subgroup 1.1.4 of FGE.19 in the Flavouring Group Evaluation 203, Revision 1 (FGE.203Rev1. The Flavour Industry has provided additional genotoxicity studies for one representative substance in FGE.203, namely 2,4-decadienal [FL-no: 05.140]. Based on the available data, on newly submitted studies and on the scientific evidence from the literature, the Panel concluded that the genotoxic potential cannot be ruled out for the flavouring substances in this FGE.
Cindy Gu
2011-01-01
What comes to mind when you think of yellow？ Sunflowers, the school bus or the smiley face？ As a food-junkie and a health nut, when I hear the word yellow, savory soy beans, munchy bananas and sweet corn are things that pop into my mind. That＇s how much I love food. Hopeless？ Perhaps.
Cucurbits are an important crop of temperate, subtropical and tropical regions of the world. Cucumber vein yellowing virus (CVYV) is a major viral pathogen of cucurbits. This chapter provides an overview of the biology of CVYV and the disease it causes....
Cucurbits are an important crop of temperate, subtropical and tropical regions of the world. Squash vein yellowing virus (SqVYV) is a major viral pathogen of cucurbits. This chapter provides an overview of the biology of SqVYV and the disease it causes....
2013-01-01
Arevised traffic regulation, seen as the harshest ever by many, took effect on January 1. Accordingly, drivers who run yellow lights will have six points deducted from the 12 allocated on their licenses. Those who have any part of their vehicles crossing the line at the time of change will not be punished.
无
2005-01-01
@@ It was released on August 24,2005 by Prof. CHEN Dayuan (Da-Yuan Chen) from the CAS Institute of Zoology that the first success in cloning the Asian Yellow Goat by nuclear transfer had recently been achieved in east China's Shandong Province.
Cluster analysis of clinical data identifies fibromyalgia subgroups.
Elisa Docampo
Full Text Available INTRODUCTION: Fibromyalgia (FM is mainly characterized by widespread pain and multiple accompanying symptoms, which hinder FM assessment and management. In order to reduce FM heterogeneity we classified clinical data into simplified dimensions that were used to define FM subgroups. MATERIAL AND METHODS: 48 variables were evaluated in 1,446 Spanish FM cases fulfilling 1990 ACR FM criteria. A partitioning analysis was performed to find groups of variables similar to each other. Similarities between variables were identified and the variables were grouped into dimensions. This was performed in a subset of 559 patients, and cross-validated in the remaining 887 patients. For each sample and dimension, a composite index was obtained based on the weights of the variables included in the dimension. Finally, a clustering procedure was applied to the indexes, resulting in FM subgroups. RESULTS: VARIABLES CLUSTERED INTO THREE INDEPENDENT DIMENSIONS: "symptomatology", "comorbidities" and "clinical scales". Only the two first dimensions were considered for the construction of FM subgroups. Resulting scores classified FM samples into three subgroups: low symptomatology and comorbidities (Cluster 1, high symptomatology and comorbidities (Cluster 2, and high symptomatology but low comorbidities (Cluster 3, showing differences in measures of disease severity. CONCLUSIONS: We have identified three subgroups of FM samples in a large cohort of FM by clustering clinical data. Our analysis stresses the importance of family and personal history of FM comorbidities. Also, the resulting patient clusters could indicate different forms of the disease, relevant to future research, and might have an impact on clinical assessment.
X-s-Permutable Subgroups%X-s-置换子群
石磊; 郭文彬; 易小兰
2008-01-01
Let X be a nonempty subset of a group G.A subgroup H of G is said to be X-spermutable in G if,for every Sylow subgroup T of G,there exists an element x ∈X such that HTx=Tx H.In this paper,we obtain some results about the X-s-permutable subgroups and use them to determine the structure of some finite groups.
A complete classification of minimal non--groups
Pengfei Guo; Junxin Wang; Hailiang Zhang
2014-11-01
Let be a finite group. A subgroup of is called -permutable in if it permutes with every Sylow subgroup of , and is called a -group if all minimal subgroups and cyclic subgroups with order 4 of are -permutable in . In this paper, we give a complete classification of finite groups which are not -groups but their proper subgroups are all -groups.
Beltoft, Vibe Meister; Nørby, Karin Kristiane
Safety Authority was requested to evaluate the genotoxic potential of 14 flavouring substances in Flavouring Group Evaluation 210 (FGE.210). In FGE.210, the Panel concluded that the genotoxic potential could not be ruled out for any of the flavouring substances. In FGE.210 Revision1, the Panel co...
The group of avian sarcoma and leukosis virus (ASLV) in chickens contains six highly related subgroups, A to E and J. Four genetic loci, tva, tvb, tvc and tvj, encode for corresponding receptors that determine the susceptibility to the ASLV subgroups. The prevalence of ASLV in hosts may have imposed...
On the Normal Subgroup with Coprime -Conjugacy Class Sizes
Xianhe Zhao; Guiyun Chen; Jiaoyun Shi
2011-11-01
Let be a normal subgroup of a group . The positive integers and are the two longest sizes of the non-central -conjugacy classes of with > and (,)=1. In this paper, the structure of is determined when divides $|N/N\\cap Z(G)|$. Some known results are generalized.
Some open questions in the theory of generalized permutable subgroups
无
2009-01-01
A subgroup H of a group G is said to be weakly s-supplemented in G if H has a supplement T in G such that H ∩ T HsG, where HsG is the largest s-permutable subgroup of G contained in H. This paper constructs an example to show that the open questions 6.3 and 6.4 in J Algebra, 315: 192–209 (2007) have negative solutions, and shows that in many cases Question 6.4 is positive. A series of known results are unified and generalized.
Harrison, Nigel A; Davis, Robert E; Oropeza, Carlos; Helmick, Ericka E; Narváez, María; Eden-Green, Simon; Dollet, Michel; Dickinson, Matthew
2014-06-01
In this study, the taxonomic position and group classification of the phytoplasma associated with a lethal yellowing-type disease (LYD) of coconut (Cocos nucifera L.) in Mozambique were addressed. Pairwise similarity values based on alignment of nearly full-length 16S rRNA gene sequences (1530 bp) revealed that the Mozambique coconut phytoplasma (LYDM) shared 100% identity with a comparable sequence derived from a phytoplasma strain (LDN) responsible for Awka wilt disease of coconut in Nigeria, and shared 99.0-99.6% identity with 16S rRNA gene sequences from strains associated with Cape St Paul wilt (CSPW) disease of coconut in Ghana and Côte d'Ivoire. Similarity scores further determined that the 16S rRNA gene of the LYDM phytoplasma shared coconut LYDM phytoplasma strains from Mozambique as novel members of established group 16SrXXII, subgroup A (16SrXXII-A). Similarity coefficients of 0.97 were obtained for comparisons between subgroup 16SrXXII-A strains and CSPW phytoplasmas from Ghana and Côte d'Ivoire. On this basis, the CSPW phytoplasma strains were designated members of a novel subgroup, 16SrXXII-B.
Khmelnitskaya, Anna Borisovna; van Deemen, Adrian; Rusinowska, Agnieszka
2010-01-01
Social welfare orderings for different scales of individual utility measurement in distinct population subgroups are studied. In Khmelnitskaya (2000), employing the continuous version of Arrow’s impossibility theorem, it was shown that for combinations of independent subgroups scales every
Yellow fever vaccination in the Americas.
1984-01-01
Outbreaks of yellow fever in recent years in the Americas have prompted concern about the possible urbanization of jungle fever. Vaccination, using the 17D strain of yellow fever virus, provides an effective, practical method of large scale protection against the disease. Because yellow fever can reappear in certain areas after a 2-year dormancy period, some countries maintain routine vaccination programs in areas where jungle yellow fever is endemic. The size of the endemic area (approximately half of South America), transportation and communication difficulties, and the inability to ensure a reliable cold chain are problems facing these programs. In addition, the problem of reaching dispersed and isolated populations has been addressed by the use of mobile teams, radio monitoring, and educational methods. During yellow fever outbreaks, many countries institute massive vaccination campaigns, targeted at temporary workers and migrants. Because epidemics in South America may involve extensive areas, these campaigns may not effectively address the problem. The ped-o-jet injector method, used in Brazil and Colombia, should be used in outbreak situations, as it is effective for large-scale vaccination. Vaccine by needle, suggested for maintenance programs, should be administered to those above 1 year of age. An efficient monitoring method to avoid revaccination, and to assess immunity, should be developed. The 17D strain produces seroconversion in 95% of recipients, and most is prepared in Brazil and Colombia. But, problems with storage methods, instability in seed lots, and difficulties in large-scale production were identified in 1981 by the Pan American Health Organization and WHO. The group recommended modernization of current production techniques and further research to develop a vaccine that could be produced in cell cultures. Brazil and Colombia have acted on these recommendations, modernizing vaccine production and researching thermostabilizing media for
El Naschie, M.S. [King Abdullah Al Saud Institute of Nano and Advanced Technologies KSU, Riyadh (Saudi Arabia); Frankfurt Institute for the Advancement of Science, Frankfurt (Germany)], E-mail: Chaossf@aol.com
2008-11-15
The maximal number of elementary particles which could be expected to be found within a modestly extended energy scale of the standard model was found using various methods to be N = 69. In particular using E-infinity theory the present Author found the exact transfinite expectation value to be
Linge, Annett; Lohaus, Fabian; Löck, Steffen
2016-01-01
carcinoma (HNSCC), who received primary radiochemotherapy (RCTx). MATERIALS AND METHODS: For 158 patients with locally advanced HNSCC of the oral cavity, oropharynx or hypopharynx who were treated at six DKTK partner sites, the impact of tumour volume, HPV DNA, p16 overexpression, p53 expression, CSC marker...... expression and hypoxia-associated gene signatures on outcome of primary RCTx was retrospectively analyzed. The primary endpoint of this study was loco-regional control (LRC). RESULTS: Univariate Cox regression revealed a significant impact of tumour volume, p16 overexpression, and SLC3A2 and CD44 protein......-negative group). Logistic modelling showed that inclusion of CD44 protein expression and p16 overexpression significantly improved the performance to predict LRC at 2years compared to the model with tumour volume alone. CONCLUSIONS: Tumour volume, HPV status, CSC marker expression and hypoxia gene...
Yellow Fever Vaccine: What You Need to Know
... www. immunize. org/ vis 1 What is yellow fever? Yellow fever is a serious disease caused by the ... serious cases) 2 How can I prevent yellow fever? Yellow fever vaccine Yellow fever vaccine can prevent yellow ...
Kasenda, Benjamin; Schandelmaier, Stefan; Sun, Xin; von Elm, Erik; You, John; Blümle, Anette; Tomonaga, Yuki; Saccilotto, Ramon; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J; Stegert, Mihaela; Olu, Kelechi K; Tikkinen, Kari A O; Neumann, Ignacio; Carrasco-Labra, Alonso; Faulhaber, Markus; Mulla, Sohail M; Mertz, Dominik; Akl, Elie A; Bassler, Dirk; Busse, Jason W; Ferreira-González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Rosenthal, Rachel; Ebrahim, Shanil; Vandvik, Per O; Johnston, Bradley C; Walter, Martin A; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G; Bucher, Heiner C; Guyatt, Gordon H; Briel, Matthias
2014-07-16
To investigate the planning of subgroup analyses in protocols of randomised controlled trials and the agreement with corresponding full journal publications. Cohort of protocols of randomised controlled trial and subsequent full journal publications. Six research ethics committees in Switzerland, Germany, and Canada. 894 protocols of randomised controlled trial involving patients approved by participating research ethics committees between 2000 and 2003 and 515 subsequent full journal publications. Of 894 protocols of randomised controlled trials, 252 (28.2%) included one or more planned subgroup analyses. Of those, 17 (6.7%) provided a clear hypothesis for at least one subgroup analysis, 10 (4.0%) anticipated the direction of a subgroup effect, and 87 (34.5%) planned a statistical test for interaction. Industry sponsored trials more often planned subgroup analyses compared with investigator sponsored trials (195/551 (35.4%) v 57/343 (16.6%), P<0.001). Of 515 identified journal publications, 246 (47.8%) reported at least one subgroup analysis. In 81 (32.9%) of the 246 publications reporting subgroup analyses, authors stated that subgroup analyses were prespecified, but this was not supported by 28 (34.6%) corresponding protocols. In 86 publications, authors claimed a subgroup effect, but only 36 (41.9%) corresponding protocols reported a planned subgroup analysis. Subgroup analyses are insufficiently described in the protocols of randomised controlled trials submitted to research ethics committees, and investigators rarely specify the anticipated direction of subgroup effects. More than one third of statements in publications of randomised controlled trials about subgroup prespecification had no documentation in the corresponding protocols. Definitive judgments regarding credibility of claimed subgroup effects are not possible without access to protocols and analysis plans of randomised controlled trials. © The DISCO study group 2014.
Subgroup effects despite homogeneous heterogeneity test results
Lubsen Jacobus
2010-05-01
Full Text Available Abstract Background Statistical tests of heterogeneity are very popular in meta-analyses, as heterogeneity might indicate subgroup effects. Lack of demonstrable statistical heterogeneity, however, might obscure clinical heterogeneity, meaning clinically relevant subgroup effects. Methods A qualitative, visual method to explore the potential for subgroup effects was provided by a modification of the forest plot, i.e., adding a vertical axis indicating the proportion of a subgroup variable in the individual trials. Such a plot was used to assess the potential for clinically relevant subgroup effects and was illustrated by a clinical example on the effects of antibiotics in children with acute otitis media. Results Statistical tests did not indicate heterogeneity in the meta-analysis on the effects of amoxicillin on acute otitis media (Q = 3.29, p = 0.51; I2 = 0%; T2 = 0. Nevertheless, in a modified forest plot, in which the individual trials were ordered by the proportion of children with bilateral otitis, a clear relation between bilaterality and treatment effects was observed (which was also found in an individual patient data meta-analysis of the included trials: p-value for interaction 0.021. Conclusions A modification of the forest plot, by including an additional (vertical axis indicating the proportion of a certain subgroup variable, is a qualitative, visual, and easy-to-interpret method to explore potential subgroup effects in studies included in meta-analyses.
Subgroup identification from randomized clinical trial data.
Foster, Jared C; Taylor, Jeremy M G; Ruberg, Stephen J
2011-10-30
We consider the problem of identifying a subgroup of patients who may have an enhanced treatment effect in a randomized clinical trial, and it is desirable that the subgroup be defined by a limited number of covariates. For this problem, the development of a standard, pre-determined strategy may help to avoid the well-known dangers of subgroup analysis. We present a method developed to find subgroups of enhanced treatment effect. This method, referred to as 'Virtual Twins', involves predicting response probabilities for treatment and control 'twins' for each subject. The difference in these probabilities is then used as the outcome in a classification or regression tree, which can potentially include any set of the covariates. We define a measure Q(Â) to be the difference between the treatment effect in estimated subgroup Â and the marginal treatment effect. We present several methods developed to obtain an estimate of Q(Â), including estimation of Q(Â) using estimated probabilities in the original data, using estimated probabilities in newly simulated data, two cross-validation-based approaches, and a bootstrap-based bias-corrected approach. Results of a simulation study indicate that the Virtual Twins method noticeably outperforms logistic regression with forward selection when a true subgroup of enhanced treatment effect exists. Generally, large sample sizes or strong enhanced treatment effects are needed for subgroup estimation. As an illustration, we apply the proposed methods to data from a randomized clinical trial.
Clinically relevant subgroups in COPD and asthma
Alice M. Turner
2015-06-01
Full Text Available As knowledge of airways disease has grown, it has become apparent that neither chronic obstructive pulmonary disease (COPD nor asthma is a simple, easily defined disease. In the past, treatment options for both diseases were limited; thus, there was less need to define subgroups. As treatment options have grown, so has our need to predict who will respond to new drugs. To date, identifying subgroups has been largely reported by detailed clinical characterisation or differences in pathobiology. These subgroups are commonly called “phenotypes”; however, the problem of defining what constitutes a phenotype, whether this should include comorbid diseases and how to handle changes over time has led to the term being used loosely. In this review, we describe subgroups of COPD and asthma patients whose clinical characteristics we believe have therapeutic or major prognostic implications specific to the lung, and whether these subgroups are constant over time. Finally, we will discuss whether the subgroups we describe are common to both asthma and COPD, and give some examples of how treatment might be tailored in patients where the subgroup is clear, but the label of asthma or COPD is not.
Identification of subgroups among fibromyalgia patients
D. Chaleil
2012-09-01
Full Text Available This paper presents some hypotheses concerning the identification of homogeneous subgroups among fibromyalgia (FM patients in order to improve the management of the disease. It also reviews the available literature about this subject. Three methods for subgrouping are discussed according to clinical features, biomarkers, and gait analysis. Clinical subgrouping based on cluster analysis has been used for the identification of homogeneous subgroups of patients and, more recently, homogeneous clinical features. So far, longitudinal studies using clinical subgroups to direct treatment and predict outcome are still required. Biomarkers in FM, which is a neurobiological disease, are of promising interest, nevertheless currently, none of them can be used to subgroup FM patients. Due to the fact that cortical and subcortical mechanisms of gait control share some cognitive functions which are involved in FM, gait markers have been proposed to evaluate and to subgroup FM patients, in clinical settings. Three out of 4 core FM symptoms are linked to gait markers. Kinesia measured by means of cranio-caudal power is correlated to pain, and could be proposed to assess pain behavior (kinesiophobia. Stride frequency, which is linked to physical component, allows the identification of a hyperkinetic subgroup. Moreover, SF has been correlated to fatigue during the 6 minute walking test. Stride regularity, which expresses the unsteadiness of gait, is correlated to cognitive dysfunction in FM. Decreased stride regularity allows the recognition of a homogeneous subgroup characterized by an increased anxiety and depression, and decreased cognitive functions. These results need further studies to be validated and so used in the daily clinical practice.
Identification of subgroups among fibromyalgia patients.
Auvinet, B; Chaleil, D
2012-09-28
This paper presents some hypotheses concerning the identification of homogeneous subgroups among fibromyalgia (FM) patients in order to improve the management of the disease. It also reviews the available literature about this subject. Three methods for subgrouping are discussed according to clinical features, biomarkers, and gait analysis. Clinical subgrouping based on cluster analysis has been used for the identification of homogeneous subgroups of patients and, more recently, homogeneous clinical features. So far, longitudinal studies using clinical subgroups to direct treatment and predict outcome are still required. Biomarkers in FM, which is a neurobiological disease, are of promising interest, nevertheless currently, none of them can be used to subgroup FM patients. Due to the fact that cortical and subcortical mechanisms of gait control share some cognitive functions which are involved in FM, gait markers have been proposed to evaluate and to subgroup FM patients, in clinical settings. Three out of 4 core FM symptoms are linked to gait markers. Kinesia measured by means of cranio-caudal power is correlated to pain, and could be proposed to assess pain behavior (kinesiophobia). Stride frequency, which is linked to physical component, allows the identification of a hyperkinetic subgroup. Moreover, SF has been correlated to fatigue during the 6 minute walking test. Stride regularity, which expresses the unsteadiness of gait, is correlated to cognitive dysfunction in FM. Decreased stride regularity allows the recognition of a homogeneous subgroup characterized by an increased anxiety and depression, and decreased cognitive functions. These results need further studies to be validated and so used in the daily clinical practice.
SUBGR: A Program to Generate Subgroup Data for the Subgroup Resonance Self-Shielding Calculation
Kim, Kang Seog [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
2016-06-06
The Subgroup Data Generation (SUBGR) program generates subgroup data, including levels and weights from the resonance self-shielded cross section table as a function of background cross section. Depending on the nuclide and the energy range, these subgroup data can be generated by (a) narrow resonance approximation, (b) pointwise flux calculations for homogeneous media; and (c) pointwise flux calculations for heterogeneous lattice cells. The latter two options are performed by the AMPX module IRFFACTOR. These subgroup data are to be used in the Consortium for Advanced Simulation of Light Water Reactors (CASL) neutronic simulator MPACT, for which the primary resonance self-shielding method is the subgroup method.
宁宇
2009-01-01
The yellow-billed stork was kept in a captive environment from 2006 to 2008. Scan sampling and the focus animals methods were used to observe yellow-billed stork breeding, nestling growth and development. The results showed that: Through human intervention, the yellow-billed stork in the Beijing area can reproduce in a whole year. The adult birds raise chicks together. Nestling birds is an altrices, compared to the ibis, the yellow-billed stork has a lot of specificity in the growth and development which close to the storks.%从2006年到2008年间对黄嘴鹮鹳的饲养环境进行人工调节,采用焦点动物法和扫描取样法对黄嘴鹮鹳的繁殖行为、雏鸟的生长发育进行观察.结果表明,人工措施可使黄嘴鹮鹳在北京地区全年繁殖;亲鸟在育雏期共同养育雏鸟;雏鸟属晚成鸟,但与鹮类相比,在生长发育上有特异性,更接近于鹳.
Psychopathic traits of Dutch adolescents in residential care: identifying subgroups.
Nijhof, Karin S; Vermulst, Ad; Scholte, Ron H J; van Dam, Coleta; Veerman, Jan Willem; Engels, Rutger C M E
2011-01-01
The present study examined whether a sample of 214 (52.8% male, M age = 15.76, SD = 1.29) institutionalized adolescents could be classified into subgroups based on psychopathic traits. Confirmatory Factor Analyses revealed a relationship between the subscales of the Youth Psychopathic traits Inventory (YPI) and the three latent constructs of the original model on which it is based. Latent Class Analyses showed that adolescents showing psychopathic traits could be classified into three subgroups. The first group showed low scores on the grandiose/manipulative dimension, the callous/unemotional dimension, and the impulsive/irresponsible dimension (normal group). The second group scored moderate on the grandiose/manipulative dimension and the callous/unemotional dimension and high on the impulsive/irresponsible dimension (impulsive, non-psychopathic-like group). The third group scored high on all three dimensions (psychopathy-like group). The findings revealed that the impulsive, non-psychopathic like group scored significantly higher on internalizing problem behavior compared to the normal group, while the psychopathy-like and the impulsive, non-psychopathic-like group both scored higher on externalizing problem behavior compared to the normal group. Based on a self-report delinquency measure, it appeared that the psychopathy-like group had the highest delinquency rates, except for vandalism. Both the impulsive and psychopathy-like group had the highest scores on the use of soft drugs.
Current Activities of the ASME Subgroup NUPACK
Gerald M. Foster; D. Keith Morton; Paul McConnell
2007-10-01
Current activities of the American Society of Mechanical Engineers (ASME), Section III Subgroup on Containment Systems for Spent Fuel High-Level Waste Transport Packagings (also known as Subgroup NUPACK) are reviewed with emphasis on the recent revision of Subsection WB. Also, brief insightson new proposals for the development of rules for internal support structures and for a strain-based acceptance criteria are provided.
Maike Ahrens
Full Text Available Detection of yet unknown subgroups showing differential gene or protein expression is a frequent goal in the analysis of modern molecular data. Applications range from cancer biology over developmental biology to toxicology. Often a control and an experimental group are compared, and subgroups can be characterized by differential expression for only a subgroup-specific set of genes or proteins. Finding such genes and corresponding patient subgroups can help in understanding pathological pathways, diagnosis and defining drug targets. The size of the subgroup and the type of differential expression determine the optimal strategy for subgroup identification. To date, commonly used software packages hardly provide statistical tests and methods for the detection of such subgroups. Different univariate methods for subgroup detection are characterized and compared, both on simulated and on real data. We present an advanced design for simulation studies: Data is simulated under different distributional assumptions for the expression of the subgroup, and performance results are compared against theoretical upper bounds. For each distribution, different degrees of deviation from the majority of observations are considered for the subgroup. We evaluate classical approaches as well as various new suggestions in the context of omics data, including outlier sum, PADGE, and kurtosis. We also propose the new FisherSum score. ROC curve analysis and AUC values are used to quantify the ability of the methods to distinguish between genes or proteins with and without certain subgroup patterns. In general, FisherSum for small subgroups and t-test for large subgroups achieve best results. We apply each method to a case-control study on Parkinson's disease and underline the biological benefit of the new method.
Fifty shades of yellow: a review of the xanthodermatoses.
Frew, John W; Murrell, Dédée F; Haber, Richard M
2015-10-01
The xanthodermatoses consist of a heterogeneous group of cutaneous disorders characterized by the macroscopic yellow hue seen on examination. This hue is attributable to the chemical structure of the accumulating substances within the skin or surrounding tissues. The most common culprits are lipids (cholesterol and triglycerides), elastin, and bilirubin. Exogenous sources of yellow pigment include yellow dyes (including hennas) and metal salts. This article will focus on recognition of these entities, classified in terms of morphology and the site of initial eruption, in order to support the recognition and diagnosis of these widely variable conditions.
Nonstabilizer Quantum Codes from Abelian Subgroups of the Error Group
Arvind, V; Parthasarathy, K R; Kurur, Piyush P
2002-01-01
This paper is motivated by the computer-generated nonadditive ((5,6,2)) code described in an article by Rains, Hardin, Shor and Sloane. We describe a theory of non-stabilizer codes of which the nonadditive code of Rains et al is an example. Furthermore, we give a general strategy of constructing good nonstabilizer codes from good stabilizer codes and give some explicit constructions and asymptotically good nonstabilizer codes. In fact, we explicitly construct a family of distance 2 non-stabilizer codes over all finite fields of which the ((5,6,2)) is an special example. More interestingly, using our theory, we are also able to explicitly construct examples of non-stablizer quantum codes of distance 3. Like in the case of stabilizer codes, we can design fairly efficient encoding and decoding procedures.
Electricity market players subgroup report
Borison, A.
1990-03-01
The purpose of this study is to examine competition in the electric power industry from an ``industrial organization`` point of view. The remainder of this report is organized as follows. Chapter 2 describes the ``industrial organization`` approach used to analyze the electric power market. Industrial organization emphasizes specific market performance criteria, and the impact of market structure and behavior on performance. Chapter 3 identifies the participants in the electric power market, grouped primarily into regulated producers, unregulated producers, and consumers. Chapter 4 describes the varieties of electric power competition, organized along two dimensions: producer competition and consumer competition. Chapters 5 and 6 identify the issues raised by competition along the two dimensions. These issues include efficiency, equity, quality, and stability. Chapters 7 through 9 describe market structure, behavior and performance in three competitive scenarios: minimum competition, maximum competition, and moderate competition. Market structure, behavior and performance are discussed, and the issues raised in Chapters 5 and 6 are discussed in detail. Chapter 10 provides conclusions about ``winners and losers`` and identifies issues that require further study.
Electricity market players subgroup report
Borison, A.
1990-03-01
The purpose of this study is to examine competition in the electric power industry from an industrial organization'' point of view. The remainder of this report is organized as follows. Chapter 2 describes the industrial organization'' approach used to analyze the electric power market. Industrial organization emphasizes specific market performance criteria, and the impact of market structure and behavior on performance. Chapter 3 identifies the participants in the electric power market, grouped primarily into regulated producers, unregulated producers, and consumers. Chapter 4 describes the varieties of electric power competition, organized along two dimensions: producer competition and consumer competition. Chapters 5 and 6 identify the issues raised by competition along the two dimensions. These issues include efficiency, equity, quality, and stability. Chapters 7 through 9 describe market structure, behavior and performance in three competitive scenarios: minimum competition, maximum competition, and moderate competition. Market structure, behavior and performance are discussed, and the issues raised in Chapters 5 and 6 are discussed in detail. Chapter 10 provides conclusions about winners and losers'' and identifies issues that require further study.
Cluster Analysis of Clinical Data Identifies Fibromyalgia Subgroups
Docampo, Elisa; Collado, Antonio; Escaramís, Geòrgia; Carbonell, Jordi; Rivera, Javier; Vidal, Javier; Alegre, José
2013-01-01
Introduction Fibromyalgia (FM) is mainly characterized by widespread pain and multiple accompanying symptoms, which hinder FM assessment and management. In order to reduce FM heterogeneity we classified clinical data into simplified dimensions that were used to define FM subgroups. Material and Methods 48 variables were evaluated in 1,446 Spanish FM cases fulfilling 1990 ACR FM criteria. A partitioning analysis was performed to find groups of variables similar to each other. Similarities between variables were identified and the variables were grouped into dimensions. This was performed in a subset of 559 patients, and cross-validated in the remaining 887 patients. For each sample and dimension, a composite index was obtained based on the weights of the variables included in the dimension. Finally, a clustering procedure was applied to the indexes, resulting in FM subgroups. Results Variables clustered into three independent dimensions: “symptomatology”, “comorbidities” and “clinical scales”. Only the two first dimensions were considered for the construction of FM subgroups. Resulting scores classified FM samples into three subgroups: low symptomatology and comorbidities (Cluster 1), high symptomatology and comorbidities (Cluster 2), and high symptomatology but low comorbidities (Cluster 3), showing differences in measures of disease severity. Conclusions We have identified three subgroups of FM samples in a large cohort of FM by clustering clinical data. Our analysis stresses the importance of family and personal history of FM comorbidities. Also, the resulting patient clusters could indicate different forms of the disease, relevant to future research, and might have an impact on clinical assessment. PMID:24098674
A short proof of the Khukhro-Makarenko theorem on large characteristic subgroups with laws
Klyachko, Anton A.; Mel'nikova, Yuliya B.
2009-06-01
We give a short proof and a somewhat stronger version of the Khukhro-Makarenko theorem that each group which virtually satisfies an outer commutator identity contains a finite-index characteristic subgroup satisfying this identity. An estimate for the index of this characteristic subgroup is obtained. Bibliography: 3 titles.
Pedro Fernando da Costa Vasconcelos
2003-04-01
Full Text Available A febre amarela é doenca infecciosa não-contagiosa causada por um arbovírus mantido em ciclos silvestres em que macacos atuam como hospedeiros amplificadores e mosquitos dos gêneros Aedes na África, e Haemagogus e Sabethes na América, são os transmissores. Cerca de 90% dos casos da doença apresentam-se com formas clínicas benignas que evoluem para a cura, enquanto 10% desenvolvem quadros dramáticos com mortalidade em torno de 50%. O problema mostra-se mais grave em África onde ainda há casos urbanos. Nas Américas, no período de 1970-2001, descreveram-se 4.543 casos. Os países que mais diagnosticaram a doença foram o Peru (51,5%, a Bolívia (20,1% e o Brasil (18,7%. Os métodos diagnósticos utilizados incluem a sorologia (IgM, isolamento viral, imunohistoquímica e RT-PCR. A zoonose não pode ser erradicada, mas, a doença humana é prevenível mediante a vacinação com a amostra 17D do vírus amarílico. A OMS recomenda nova vacinação a cada 10 anos. Neste artigo são revistos os principais conceitos da doença e os casos de mortes associados à vacina.Yellow fever is an infectious and non-contagious disease caused by an arbovirus, the yellow fever virus. The agent is maintained in jungle cycles among primates as vertebrate hosts and mosquitoes, especially Aedes in Africa, and Haemagogus and Sabethes in America. Approximately 90% of the infections are mild or asymptomatic, while 10% course to a severe clinical picture with 50% case-fatality rate. Yellow fever is largely distributed in Africa where urban epidemics are still reported. In South America, between 1970-2001, 4,543 cases were reported, mostly from Peru (51.5%, Bolivia (20.1% and Brazil (18.7%. The disease is diagnosed by serology (detection of IgM, virus isolation, immunohistochemistry and RT-PCR. Yellow fever is a zoonosis and cannot be eradicated, but it is preventable in man by using the 17D vaccine. A single dose is enough to protect an individual for at least
Subgroup conflicts? Try the psychodramatic "double triad method".
Verhofstadt-Denève, Leni M F
2012-04-01
The present article suggests the application of a psychodramatic action method for tackling subgroup conflicts in which the direct dialogue between representatives of two opposing subgroups is prepared step by step through an indirect dialogue strategy within two triads, a strategy known as the Double Triad Method (DTM). In order to achieve integration in the group as a whole, it is important that all the members of both subgroups participate actively during the entire process. The first part of the article briefly explores the theoretical background, with a special emphasis on the Phenomenological-Dialectical Personality Model (Phe-Di PModel). In the second part, the DTM procedure is systematically described through its five action stages, each accompanied with 1) a spatial representation of the consecutive actions, 2) some illustrative statements for each stage, and 3) a theoretical interpretation of the dialectically involved personality dimensions in both protagonists. The article concludes with a discussion and suggestions for more extensive applications of the DTM method, including the question of its relationships to Agazarian's functional subgrouping, psychodrama, and sociodrama.
In 2016, many parts of the Midwest experienced far wetter than normal summer weather and by August or September, many growers were asking, “Why is my alfalfa yellow?” When all or part of an alfalfa field is yellow, it is a certain sign that something has gone wrong. In this case the problem in most ...
QiuJianghong
2004-01-01
THE China film market is based on the so-called battle of the yellow, green and red.Yellow is American Kodak,green Japanese Fuji color, and red China's Lucky film, local counterweight to the two world-famous foreigners.
Photo yellowing of human hair.
Nogueira, A C S; Richena, M; Dicelio, L E; Joekes, I
2007-09-25
In general, human hair is claimed to turn yellower after sun exposure. This is particularly affirmed for white hair. However, quantitative data relating yellowness to hair type and to the radiation wavelength are missing. This work shows results of the effect of full or UVB-filtered radiation of a mercury vapor or a xenon-arc lamp on the yellowness of virgin white, dark-brown, blond and red hair. All hair types showed a substantial change in yellowness after irradiation, which is dependent on the hair type and radiation wavelength. Surprisingly, white hair turns less yellow after both full and UVB-filtered radiation exposure. This effect is more pronounced when UVB is filtered from the radiation system. The only radiation that shows a photo-yellowing effect on white hair is infrared. As the yellowness of white hair is commonly related to tryptophan degradation, fluorescence experiments with hair solutions were performed to identify the natural degradation of tryptophan which occurs in hair after light irradiation. Pigmented hairs were also studied, as well as hair treated with a bleaching solution. Although we observe a decrease in tryptophan content of hair after lamp radiation, a direct correlation with hair yellowness was not achieved. Results are discussed in terms of hair type, composition and melanin content.
Noguchi, Hideyo
1922-01-01
Analysis of the records of instances in which non-immune persons contracted yellow fever notwithstanding vaccination shows that the onset of disease occurs soon after vaccination, the longest period being 13 days. Since the average incubation period in yellow fever is 6 days, it seems that infection must have taken place in some instances during the period while protection was developing. These instances led to a study of the possibility of immediate protection by means of the anti-icteroides serum. It had already been shown that the immune serum protects at once against experimental Leptospira icteroides infection, but it remained to determine how long the protection would last. Guinea pigs were given different quantities of the immune serum and subsequently injected, at various intervals, with a virulent strain of Leptospira icteroides. Complete protection enduring 5 days was obtained with as minute a quantity of serum as 0.002 cc. per 1,000 gm. of body weight. After 5 days, however, the immune substance rapidly diminished, and to keep the animal protected for as long as 10 days it was necessary to give 100 times as much, or 0.2 cc. For a man weighing 80 kilos, 0.16 cc. (0.002 x 80) would theoretically be sufficient to protect for at least 5 days, 1.6 cc. for 7 days, and 16 cc. for 10 days. This temporary protection may be a valuable antecedent to that furnished by vaccination, since the final effect of the latter cannot be expected until at least 9 to 10 days have passed. PMID:19868677
Electroencephalographic characterization of subgroups of children with learning disorders.
Roca-Stappung, Milene; Fernández, Thalía; Bosch-Bayard, Jorge; Harmony, Thalía; Ricardo-Garcell, Josefina
2017-01-01
Electroencephalographic alterations have been reported in subjects with learning disorders, but there is no consensus on what characterizes their electroencephalogram findings. Our objective was to determine if there were subgroups within a group of scholars with not otherwise specified learning disorders and if they had specific electroencephalographic patterns. Eighty-five subjects (31 female, 8-11 years) who scored low in at least two subscales -reading, writing and arithmetic- of the Infant Neuropsychological Evaluation were included. Electroencephalograms were recorded in 19 leads during rest with eyes closed; absolute power was obtained every 0.39 Hz. Three subgroups were formed according to children's performance: Group 1 (G1, higher scores than Group 2 in reading speed and reading and writing accuracy), Group 2 (G2, better performance than G1 in composition) and Group 3 (G3, lower scores than Groups 1 and 2 in the three subscales). G3 had higher absolute power in frequencies in the delta and theta range at left frontotemporal sites than G1 and G2. G2 had higher absolute power within alpha frequencies than G3 and G1 at the left occipital site. G3 had higher absolute power in frequencies in the beta range than G1 in parietotemporal areas and than G2 in left frontopolar and temporal sites. G1 had higher absolute power within beta frequencies than G2 in the left frontopolar site. G3 had lower gamma absolute power values than the other groups in the left hemisphere, and gamma activity was higher in G1 than in G2 in frontopolar and temporal areas. This group of children with learning disorders is very heterogeneous. Three subgroups were found with different cognitive profiles, as well as a different electroencephalographic pattern. It is important to consider these differences when planning interventions for children with learning disorders.
M. Quattrocchio
2003-03-01
Full Text Available Aproximadamente en el Eoceno medio -Fase Incaica- culminó la acumulación del Grupo Salta (Cretácico-Paleógeno. A continuación y coincidente con el inicio de un ambiente tectónico compresivo en los Andes Centrales comenzó el depósito del Subgrupo Metán (Grupo Orán, constituído por las formaciones Río Seco, Anta y Jesús María. La Formación Anta en río Piedras de 300 m de espesor, consta de arcilitas, calizas oolíticas y tobas acumuladas en un ambiente de lago salino. Se presenta en este trabajo, un análisis palinológico comparativo entre la Formación Anta (Subgrupo Metán y el Subgrupo Santa Bárbara del Grupo Salta (Paleoceno-Eoceno. Regionalmente el espectro polínico reflejaría la presencia de la foresta sub-tropical húmeda (Verrustephanoporites simplex, en muy bajo porcentaje con respecto al Subgrupo Santa Bárbara. La relativa mayor representación de Rhoipites sp. A (Rutaceae, cf. Ruta asociado a Podocarpaceae y Anacardiaceae sugiere una paleocomunidad de mayor altitud (ambiente montano. Basado en estudios palinológicos y sedimentológicos el perfil analizado corresponde a un lago salino. Se registra la primera expansión de la estepa en el NO argentino asociado a condiciones relativamente áridas. Estas evidencias fueron corroboradas mediante el registro de hongos.Deposition of the Salta Group (Cretaceous-Paleogene terminated in the mid Eocene - Inca Diastrophic Phase. Following a compressive tectonic event in the Central Andes, this was succeeded by deposition of Metán Subgroup, divisible into Río Seco, Anta and Jesús María formations. The Anta Formation (300m thick in Río Piedras is characterised by claystone, oolitic limestone and tuff deposited in shallow lakes or on a muddy plain. A comparative palynological analysis between Santa Bárbara Subgroup and Anta Formation (Metán Subgroup shows that the transitional forest flora of the Anta Formation was more impoverished than that of the Santa Bárbara Subgroup
Subgroup Discovery Algorithms：A Survey and Empirical Evaluation
Sumyea Helal
2016-01-01
Subgroup discovery is a data mining technique that discovers interesting associations among different variables with respect to a property of interest. Existing subgroup discovery methods employ different strategies for searching, pruning and ranking subgroups. It is very crucial to learn which features of a subgroup discovery algorithm should be considered for generating quality subgroups. In this regard, a number of reviews have been conducted on subgroup discovery. Although they provide a broad overview on some popular subgroup discovery methods, they employ few datasets and measures for subgroup evaluation. In the light of the existing measures, the subgroups cannot be appraised from all perspectives. Our work performs an extensive analysis on some popular subgroup discovery methods by using a wide range of datasets and by defining new measures for subgroup evaluation. The analysis result will help with understanding the major subgroup discovery methods, uncovering the gaps for further improvement and selecting the suitable category of algorithms for specific application domains.
Groups of Prime Power Order v. 3
Berkovich, Yakov
2011-01-01
This is the third volume of a comprehensive and elementary treatment of finite p-group theory. Topics covered in this volume: (a) impact of minimal nonabelian subgroups on the structure of p-groups, (b) classification of groups all of whose nonnormal subgroups have the same order, (c) degrees of irreducible characters of p-groups associated with finite algebras, (d) groups covered by few proper subgroups, (e) p-groups of element breadth 2 and subgroup breadth 1, (f) exact number of subgroups of given order in a metacyclic p-group, (g) soft subgroups, (h) p-groups with a maximal elementary abel
Universal primers that amplify RNA from all three flavivirus subgroups
Barnard Ross T
2008-01-01
Full Text Available Abstract Background Species within the Flavivirus genus pose public health problems around the world. Increasing cases of Dengue and Japanese encephalitis virus in Asia, frequent outbreaks of Yellow fever virus in Africa and South America, and the ongoing spread of West Nile virus throughout the Americas, show the geographical burden of flavivirus diseases. Flavivirus infections are often indistinct from and confused with other febrile illnesses. Here we review the specificity of published primers, and describe a new universal primer pair that can detect a wide range of flaviviruses, including viruses from each of the recognised subgroups. Results Bioinformatic analysis of 257 published full-length Flavivirus genomes revealed conserved regions not previously targeted by primers. Two degenerate primers, Flav100F and Flav200R were designed from these regions and used to generate an 800 base pair cDNA product. The region amplified encoded part of the methyltransferase and most of the RNA-dependent-RNA-polymerase (NS5 coding sequence. One-step RT-PCR testing was successful using standard conditions with RNA from over 60 different flavivirus strains representing about 50 species. The cDNA from each virus isolate was sequenced then used in phylogenetic analyses and database searches to confirm the identity of the template RNA. Conclusion Comprehensive testing has revealed the broad specificity of these primers. We briefly discuss the advantages and uses of these universal primers.
Li, Hongxin; Xue, Chunyi; Ji, Jun; Chang, Shuang; Shang, Huiqin; Zhang, Lingjun; Ma, Jingyun; Bi, Yingzuo; Xie, Qingmei
2012-11-01
Subgroup J avian leukosis virus (ALV-J) isolate GDKP1202 was isolated from a 50-day-old local yellow commercial broiler in the Guangdong province of China in 2012. Here we report the complete genomic sequence of the GDKP1202 isolate, which caused high mortality, serious growth suppression, thymic atrophy, and liver enlargement in commercial broilers. A novel potential binding site (5'-GGCACCTCC-3') for c-myb was identified in the GDKP1202 genome. These findings will provide additional insights into the molecular characteristics in the genomes and pathogenicity of ALV-J.
Does a yellow filter improve visual object categorization in normal aging?
Lenoble, Quentin; Boucart, Muriel; Rougier, Marie-Bénédicte; Bordaberry, Pierre; Delord, Sandrine
2014-01-01
Previous studies have shown that a yellow filter (CPF450) can increase contrast, motion sensitivity, vergence, and accommodation. We investigated whether a yellow filter can reduce age-related visual deficits. We tested two groups of 60 observers (mean age 24 vs. 72) in an object categorization task. Grayscale photographs of natural objects and artifacts were displayed either centrally or peripherally (21°) at low (8%) or medium (30%) contrast. There were three filter conditions (no filter, placebo filter, and yellow filter). Both groups of observers performed similarly on central and medium-contrast pictures. The deleterious effects of reduced contrast and eccentricity were stronger in elderly individuals. Moreover, the yellow filter globally improved the speed of categorization for the elderly participants. The decrease in response time in the yellow filter condition was larger when the stimuli were displayed peripherally in both groups. A yellow filter should be considered as a potential means for visual improvement in normal aging.
Rapid diagnosis of medulloblastoma molecular subgroups
Schwalbe, Ed C.; Lindsey, Janet C.; Straughton, Debbie; Hogg, Twala L.; Cole, Michael; Megahed, Hisham; Ryan, Sarra L.; Lusher, Meryl E.; Taylor, Michael D.; Gilbertson, Richard J.; Ellison, David W.; Bailey, Simon; Clifford, Steven C.
2011-01-01
PURPOSE Microarray studies indicate medulloblastoma comprises distinct molecular disease subgroups, which offer potential for improved clinical management. EXPERIMENTAL DESIGN Minimal mRNA expression signatures diagnostic for the Wnt/Wingless (WNT) and Sonic Hedgehog (SHH) subgroups were developed, validated and used to assign subgroup affiliation in 173 tumours from four independent cohorts, alongside a systematic investigation of subgroup clinical and molecular characteristics. RESULTS WNT tumours (12% (21/173)) were diagnosed >5 years of age (peak, 10 years), displayed classic histology, CTNNB1 mutation (19/20), associated chromosome 6 loss and have previously been associated with favourable prognosis. SHH cases (24% (42/173)) predominated in infants (<3 years) and showed an age-dependent relationship to desmoplastic/nodular pathology; all infant desmoplastic/nodular cases (previously associated with a good outcome) were SHH-positive, but these relationships broke down in non-infants. PTCH1 mutations were common (34%; 11/32), but PTCH1 exon1c hypermethylation, chromosome 9q and REN (KCTD11) genetic loss were not SHH-associated, and SMO or SUFU mutation, PTCH1 exon1a or SUFU hypermethylation did not play a role, indicating novel activating mechanisms in the majority of SHH cases. SHH tumours were associated with an absence of COL1A2 methylation. WNT/SHH-independent medulloblastomas (64% (110/173)) showed all histologies, peaked at 3-6 years, and were exclusively associated with chromosome 17p loss. CONCLUSIONS Medulloblastoma subgroups are characterised by distinct genomic, epigenomic and clinico-pathological features, and clinical outcomes. Validated array-independent gene expression assays for the rapid assessment of subgroup affiliation in small biopsies, provide a basis for their routine clinical application, in strategies including molecular disease-risk stratification and delivery of targeted therapeutics. PMID:21325292
The effect of a yellow bicycle jacket on cyclist accidents
Lahrmann, Harry; Madsen, Tanja Kidholm Osmann; Olesen, Anne Vingaard
2017-01-01
Highlights •A randomised controlled trial with 6793 cyclists shows a reduced accident risk due to a yellow bicycle jacket. •The test group had 47% fewer multiparty accidents with personal injury. •The test group had 55% fewer multiparty accidents against motorised vehicles.......Highlights •A randomised controlled trial with 6793 cyclists shows a reduced accident risk due to a yellow bicycle jacket. •The test group had 47% fewer multiparty accidents with personal injury. •The test group had 55% fewer multiparty accidents against motorised vehicles....
António J Santos
Full Text Available Recent studies of school-age children and adolescents have used social network analyses to characterize selection and socialization aspects of peer groups. Fewer network studies have been reported for preschool classrooms and many of those have focused on structural descriptions of peer networks, and/or, on selection processes rather than on social functions of subgroup membership. In this study we started by identifying and describing different types of affiliative subgroups (HMP- high mutual proximity, LMP- low mutual proximity, and ungrouped children in a sample of 240 Portuguese preschool children using nearest neighbor observations. Next, we used additional behavioral observations and sociometric data to show that HMP and LMP subgroups are functionally distinct: HMP subgroups appear to reflect friendship relations, whereas LMP subgroups appear to reflect common social goals, but without strong, within-subgroup dyadic ties. Finally, we examined the longitudinal implications of subgroup membership and show that children classified as HMP in consecutive years had more reciprocated friendships than did children whose subgroup classification changed from LMP or ungrouped to HMP. These results extend previous findings reported for North American peer groups.
Khmelnitskaya, Anna B.; Deemen, van Adrian; Rusinowska, Agnieszka
2010-01-01
Social welfare orderings for different scales of individual utility measurement in distinct population subgroups are studied. In Khmelnitskaya (2000), employing the continuous version of Arrow’s impossibility theorem, it was shown that for combinations of independent subgroups scales every correspon
A 6-gene signature identifies four molecular subgroups of neuroblastoma
Kogner Per
2011-04-01
Full Text Available Abstract Background There are currently three postulated genomic subtypes of the childhood tumour neuroblastoma (NB; Type 1, Type 2A, and Type 2B. The most aggressive forms of NB are characterized by amplification of the oncogene MYCN (MNA and low expression of the favourable marker NTRK1. Recently, mutations or high expression of the familial predisposition gene Anaplastic Lymphoma Kinase (ALK was associated to unfavourable biology of sporadic NB. Also, various other genes have been linked to NB pathogenesis. Results The present study explores subgroup discrimination by gene expression profiling using three published microarray studies on NB (47 samples. Four distinct clusters were identified by Principal Components Analysis (PCA in two separate data sets, which could be verified by an unsupervised hierarchical clustering in a third independent data set (101 NB samples using a set of 74 discriminative genes. The expression signature of six NB-associated genes ALK, BIRC5, CCND1, MYCN, NTRK1, and PHOX2B, significantly discriminated the four clusters (p ALK, BIRC5, and PHOX2B, and was significantly associated with higher tumour stage, poor outcome and poor survival compared to the Type 1-corresponding favourable group (INSS stage 4 and/or dead of disease, p Conclusions Based on expression profiling we have identified four molecular subgroups of neuroblastoma, which can be distinguished by a 6-gene signature. The fourth subgroup has not been described elsewhere, and efforts are currently made to further investigate this group's specific characteristics.
For Distinguishing Conjugate Hidden Subgroups, the Pretty Good Measurement is as Good as it Gets
Moore, Cristopher; Moore, Cristopher; Russell, Alexander
2005-01-01
Recently Bacon, Childs and van Dam showed that the ``pretty good measurement'' (PGM) is optimal for the Hidden Subgroup Problem on the dihedral group D_n in the case where the hidden subgroup is chosen uniformly from the n involutions. We show that, for any group and any subgroup H, the PGM is the optimal one-register experiment in the case where the hidden subgroup is a uniformly random conjugate of H. We go on to show that when H forms a Gel'fand pair with its parent group, the PGM is the optimal measurement for any number of registers. In both cases we bound the probability that the optimal measurement succeeds. This generalizes the case of the dihedral group, and includes a number of other examples of interest.
Computational approaches to Poisson traces associated to finite subgroups of Sp(2n,C)
Etingof, Pavel; Pacchiano, Aldo; Ren, Qingchun; Schedler, Travis
2011-01-01
We reduce the computation of Poisson traces on quotients of symplectic vector spaces by finite subgroups of symplectic automorphisms to a finite one, by proving several results which bound the degrees of such traces as well as the dimension in each degree. This applies more generally to traces on all polynomial functions which are invariant under invariant Hamiltonian flow. We implement these approaches by computer together with direct computation for infinite families of groups, focusing on complex reflection and abelian subgroups of GL(2,C) < Sp(4,C), Coxeter groups of rank <= 3 and A_4, B_4=C_4, and D_4, and subgroups of SL(2,C).
Assessing Subgroup Differences in Item Response Times.
Schnipke, Deborah L.; Pashley, Peter J.
Differences in test performance on time-limited tests may be due in part to differential response-time rates between subgroups, rather than real differences in the knowledge, skills, or developed abilities of interest. With computer-administered tests, response times are available and may be used to address this issue. This study investigates…
Zero-Sum Problems with Subgroup Weights
S D Adhikari; A A Ambily; B Sury
2010-06-01
In this note, we generalize some theorems on zero-sums with weights from [1], [4] and [5] in two directions. In particular, we consider $\\mathbb{Z}^d_p$ for a general and subgroups of $Z^∗_p$ as weights.
Bomhard, E; Löser, E; Dornemann, A; Schilde, B
1982-12-01
The inorganic pigments nickel rutile yellow and chrome rutile yellow were fed to groups of 15 male and 15 female rats each for 3 months at dietary levels of 0, 10, 100, 1000 and 10000 ppm, respectively. On an additional 5 animals each, levels of nickel and antimony or chromium and antimony in liver and kidneys, respectively, were measured after 1 and 2 months. Appearance, behaviour, food consumption, growth, mortality, haematological and clinical chemical data, organ weights, and gross and micromorphology of organs were not affected in any dose group. In livers and kidneys antimony median levels below 30 ppb were detectable only in the group of rats fed the highest level of 10000 ppm of the two pigments.
Ankeny - Yellow Flag Iris Control
US Fish and Wildlife Service, Department of the Interior — This project aims to inventory and map all existing stands of yellow flag iris within wetland habitats at Ankeny NWR, treat them with herbicide in late spring and...
Finite Symplectic Matrix Groups
2011-01-01
The finite subgroups of GL(m, Q) are those subgroups that fix a full lattice in Q^m together with some positive definite symmetric form. A subgroup of GL(m, Q) is called symplectic, if it fixes a nondegenerate skewsymmetric form. Such groups only exist if m is even. A symplectic subgroup of GL(2n, Q) is called maximal finite symplectic if it is not properly contained in some finite symplectic subgroup of GL(2n, Q). This thesis classifies all conjugacy classes of maximal finite symplectic subg...
Male breast cancer: Looking for better prognostic subgroups.
Abreu, Miguel Henriques; Afonso, Noémia; Abreu, Pedro Henriques; Menezes, Francisco; Lopes, Paula; Henrique, Rui; Pereira, Deolinda; Lopes, Carlos
2016-04-01
Male Breast Cancer (MBC) remains a poor understood disease. Prognostic factors are not well established and specific prognostic subgroups are warranted. Retrospectively revision of 111 cases treated in the same Cancer Center. Blinded-central pathological revision with immunohistochemical (IHQ) analysis for estrogen (ER), progesterone (PR) and androgen (AR) receptors, HER2, ki67 and p53 was done. Cox regression model was used for uni/multivariate survival analysis. Two classifications of Female Breast Cancer (FBC) subgroups (based in ER, PR, HER2, 2000 classification, and in ER, PR, HER2, ki67, 2013 classification) were used to achieve their prognostic value in MBC patients. Hierarchical clustering was performed to define subgroups based on the six-IHQ panel. According to FBC classifications, the majority of tumors were luminal: A (89.2%; 60.0%) and B (7.2%; 35.8%). Triple negative phenotype was infrequent (2.7%; 3.2%) and HER2 enriched, non-luminal, was rare (≤1% in both). In multivariate analysis the poor prognostic factors were: size >2 cm (HR:1.8; 95%CI:1.0-3.4 years, p = 0.049), absence of ER (HR:4.9; 95%CI:1.7-14.3 years, p = 0.004) and presence of distant metastasis (HR:5.3; 95%CI:2.2-3.1 years, p 0.20). Clustering defined different subgroups, that have prognostic value in multivariate analysis (p = 0.005), with better survival in ER/PR+, AR-, HER2-and ki67/p53 low group (median: 11.5 years; 95%CI: 6.2-16.8 years) and worst in PR-group (median:4.5 years; 95%CI: 1.6-7.8 years). FBC subtypes do not give the same prognostic information in MBC even in luminal groups. Two subgroups with distinct prognosis were identified in a common six-IHQ panel. Future studies must achieve their real prognostic value in these patients. Copyright © 2015 Elsevier Ltd. All rights reserved.
Measuring the Speed of Aging across Population Subgroups
2014-01-01
People in different subgroups age at different rates. Surveys containing biomarkers can be used to assess these subgroup differences. We illustrate this using hand-grip strength to produce an easily interpretable, physical-based measure that allows us to compare characteristic-based ages across educational subgroups in the United States. Hand-grip strength has been shown to be a good predictor of future mortality and morbidity, and therefore a useful indicator of population aging. Data from the Health and Retirement Survey (HRS) were used. Two education subgroups were distinguished, those with less than a high school diploma and those with more education. Regressions on hand-grip strength were run for each sex and race using age and education, their interactions and other covariates as independent variables. Ages of identical mean hand-grip strength across education groups were compared for people in the age range 60 to 80. The hand-grip strength of 65 year old white males with less education was the equivalent to that of 69.6 (68.2, 70.9) year old white men with more education, indicating that the more educated men had aged more slowly. This is a constant characteristic age, as defined in the Sanderson and Scherbov article “The characteristics approach to the measurement of population aging” published 2013 in Population and Development Review. Sixty-five year old white females with less education had the same average hand-grip strength as 69.4 (68.2, 70.7) year old white women with more education. African-American women at ages 60 and 65 with more education also aged more slowly than their less educated counterparts. African American men with more education aged at about the same rate as those with less education. This paper expands the toolkit of those interested in population aging by showing how survey data can be used to measure the differential extent of aging across subpopulations. PMID:24806337
Ramaswamy, Manimekalai; Nair, Smita; Soumya, V P; Thomas, George V
2013-04-01
Yellow leaf disease (YLD) with phytoplasmal aetiology is a serious disease of arecanut palm in India. The present study was undertaken to characterize the 16S rRNA and secA gene sequences of the Indian arecanut YLD phytoplasma for 'Candidatus Phytoplasma' species assignment and 16Sr group/subgroup classification. Phytoplasma 16S rRNA genes were amplified using three sets of semi-nested/nested primers, 1F7/7R3-1F7/7R2, 4Fwd/3Rev-4Fwd/5Rev and P1/P7-R16F2n/R16R2, producing amplicons of 491, 1150 and 1250 bp, respectively, from diseased samples. The amplicons were cloned and sequenced. A blast search showed that the sequences had 99 % similarity with sugar cane white leaf phytoplasma (16SrXI) and Napier grass stunt phytoplasma (16SrXI). Phylogenetic analysis based on the 16S rRNA gene revealed the clustering of YLD phytoplasma with the rice yellow dwarf and Bermuda grass white leaf groups. The YLD phytoplasma F2nR2 sequence shared 97.5 % identity with that of 'Candidatus Phytoplasma oryzae' and 97.8 % identity with that of 'Candidatus Phytoplasma cynodontis'. Hence, for finer differentiation, we examined the secA gene-based phylogeny, where the YLD phytoplasma clustered with Napier grass stunt and sugar cane grassy shoot phytoplasmas, both belonging to the rice yellow dwarf group. Hence, we are assigning the Indian arecanut YLD phytoplasma as a 'Candidatus Phytoplasma oryzae'-related strain. Virtual RFLP analysis of a 1.2 kb fragment of the 16S rRNA gene (F2nR2 region) identified the Indian arecanut YLD phytoplasma as a member of 16SrXI-B subgroup. We name the phytoplasma Indian yellow leaf disease phytoplasma, to differentiate it from the Hainan YLD phytoplasma, which belongs to group 16SrI.
Genetic Diversity of Testa Pigments and RAPD Marker of Yellow-Seeded Rapeseed (Brassica napus L.)
ZHANG Xue-kun; CHEN Li; YIN Jia-ming; TANG Zhang-lin; LI Jia-na
2003-01-01
14 yellow-seeded rapeseed lines (Brassia napus L. ) from different genetic sources were used toanalyze diversity of testa pigments content, oil and protein content, and RAPD markers. The results showedthat the anthocyanin and melanin were the most important pigments in testa and their content were responsiblefor the variation in seed color ranging from orange to black yellow, 14 yellow-seeded lines could be classifiedinto 3 groups., high anthocyanin content group with anthocyanin content over 2.54 mg g-1 DW, the seed colorwas light yellow or orange; low pigments content group with low content of anthocyanin and melanin, the testawas transparent and the seed color was light yellow, greenish yellow or twany; high melanin content groupwith melanin content over 178.4U(A290nm), the testa was black, the seed color was black yellow. Oil eantentchanged from 36.2% to 45.5%, protein content from 21.1% to 27.7%, and the correlation analysis revealedthat the oil content is highly significantly negatively correlated with the protein content. The cluster analysisshowed that the extensive genetic variation existed among 14 yellow-seeded lines by using unweighted pairedgroup method with arithmetic average (UPGMA) based on RAPD markers which were amplified with decamerprimers, the genetic similarity among them ranged from 0.25 to 0. 909, and 14 yellow-seeded lines could putinto 2 clusters corresponding to genome difference.
Clinical subgroups in bilateral Meniere disease
2016-01-01
Meniere disease (MD) is a heterogeneous clinical condition characterized by sensorineural hearing loss, episodic vestibular symptoms and tinnitus associated with several comorbidities such as migraine or autoimmune disorders (AD). The frequency of bilateral involvement may range from 5-50% and it depends on the duration of the disease. We have performed a two-step cluster analysis in 398 patients with bilateral MD to identify the best predictors to define clinical subgroups with a potential d...
First finding of subgroup-E avian leukosis virus from wild ducks in China.
Hao, Ruijun; Han, Chunyan; Liu, Lanlan; Zeng, Xiangwei
2014-10-10
To analyze the status of avian leukosis virus subgroup E (ALV-E) in wild ducks in China, we collected 276 wild ducks, including 12 species, from four provinces of China. The PCR detection for ALV-E identified four samples as positive samples and the detection rate was 1.45%. The env sequences of ALV-E were cloned and sequenced. In gp85, genes of the four ALV-E strains showed a high homology (98.1-99.5%) with ev-1, ev-3, and SD0501 and more than 90% homology with other subgroup-A and subgroup-B avian leukosis viruses. However, they showed a slightly lower identity with subgroup-J (NX0101 and HPRS103), from 47.5 to 48.1%. Simultaneously, a further comparison with ALV-E representative isolates indicated that the amino acid substitutions of the four wild duck strains were distributed throughout the gp85. In total, these results suggested that the subgroup-E avian leukosis virus has been found in wild ducks in China.
Cluster Analysis to Identify Possible Subgroups in Tinnitus Patients.
van den Berge, Minke J C; Free, Rolien H; Arnold, Rosemarie; de Kleine, Emile; Hofman, Rutger; van Dijk, J Marc C; van Dijk, Pim
2017-01-01
In tinnitus treatment, there is a tendency to shift from a "one size fits all" to a more individual, patient-tailored approach. Insight in the heterogeneity of the tinnitus spectrum might improve the management of tinnitus patients in terms of choice of treatment and identification of patients with severe mental distress. The goal of this study was to identify subgroups in a large group of tinnitus patients. Data were collected from patients with severe tinnitus complaints visiting our tertiary referral tinnitus care group at the University Medical Center Groningen. Patient-reported and physician-reported variables were collected during their visit to our clinic. Cluster analyses were used to characterize subgroups. For the selection of the right variables to enter in the cluster analysis, two approaches were used: (1) variable reduction with principle component analysis and (2) variable selection based on expert opinion. Various variables of 1,783 tinnitus patients were included in the analyses. Cluster analysis (1) included 976 patients and resulted in a four-cluster solution. The effect of external influences was the most discriminative between the groups, or clusters, of patients. The "silhouette measure" of the cluster outcome was low (0.2), indicating a "no substantial" cluster structure. Cluster analysis (2) included 761 patients and resulted in a three-cluster solution, comparable to the first analysis. Again, a "no substantial" cluster structure was found (0.2). Two cluster analyses on a large database of tinnitus patients revealed that clusters of patients are mostly formed by a different response of external influences on their disease. However, both cluster outcomes based on this dataset showed a poor stability, suggesting that our tinnitus population comprises a continuum rather than a number of clearly defined subgroups.
A 6-gene signature identifies four molecular subgroups of neuroblastoma
Abel, Frida
2011-04-14
Abstract Background There are currently three postulated genomic subtypes of the childhood tumour neuroblastoma (NB); Type 1, Type 2A, and Type 2B. The most aggressive forms of NB are characterized by amplification of the oncogene MYCN (MNA) and low expression of the favourable marker NTRK1. Recently, mutations or high expression of the familial predisposition gene Anaplastic Lymphoma Kinase (ALK) was associated to unfavourable biology of sporadic NB. Also, various other genes have been linked to NB pathogenesis. Results The present study explores subgroup discrimination by gene expression profiling using three published microarray studies on NB (47 samples). Four distinct clusters were identified by Principal Components Analysis (PCA) in two separate data sets, which could be verified by an unsupervised hierarchical clustering in a third independent data set (101 NB samples) using a set of 74 discriminative genes. The expression signature of six NB-associated genes ALK, BIRC5, CCND1, MYCN, NTRK1, and PHOX2B, significantly discriminated the four clusters (p < 0.05, one-way ANOVA test). PCA clusters p1, p2, and p3 were found to correspond well to the postulated subtypes 1, 2A, and 2B, respectively. Remarkably, a fourth novel cluster was detected in all three independent data sets. This cluster comprised mainly 11q-deleted MNA-negative tumours with low expression of ALK, BIRC5, and PHOX2B, and was significantly associated with higher tumour stage, poor outcome and poor survival compared to the Type 1-corresponding favourable group (INSS stage 4 and\\/or dead of disease, p < 0.05, Fisher\\'s exact test). Conclusions Based on expression profiling we have identified four molecular subgroups of neuroblastoma, which can be distinguished by a 6-gene signature. The fourth subgroup has not been described elsewhere, and efforts are currently made to further investigate this group\\'s specific characteristics.
On SQ-supplemented Subgroups%关于SQ-补子群
唐娜; 黎先华
2014-01-01
假定Fitting子群F(G)或广义Fitting子群F*(G)的某些子群在G中SQ-补来研究包含超可解群的饱和群系(ξ),这里G∈(ξ).一些已知结果被推广.%In this paper,we study a saturated formation (ξ) containing supersoluble groups under the assumption that some subgroups of a Fitting subgroup F(G) or a generalized Fitting subgroup F*(G) are SQ-supplemented in G for G ∈ (ξ).Some known results are generalized.
2007-01-01
Built as a monument to the favorite wife of the Mughal Emperor Shah Jahan, the Taj Mahal has watched over the city of Agra, India, since the mid-seventeenth century with its pillars of gleaming white marble. By the spring of 2007, however, one of the world's most visited landmarks was turning yellow, and a panel of India's parliament had little trouble identifying the culprit: pollution. The panel blamed particles of soot and dirt suspended high in the atmosphere for the Taj Mahal's dinginess. The Taj Mahal's home, Agra, sits not far from the base of the Himalaya, and smog regularly collects along the southern side of the mountain range. On May 16, 2007, the Moderate Resolution Imaging Spectroradiometer (MODIS) on NASA's Terra satellite captured this image of the area around Agra, India. The closeup image shows the immediate vicinity of the Taj Majal. The larger image shows the surrounding area. In both pictures, dingy, gray-beige haze obscures the satellite's view of the land surface. India had tried to minimize the adverse impact of air pollution on the famous landmark. According to the BBC, in the late 1990s, India's Supreme Court ordered the closure of thousands of iron foundries and kilns that had belched smoke near the monument. Many of the 3 million tourists who visited the Taj Majal each year approached the monument on horse-drawn carriages or battery-operated buses as fossil-fuel-powered vehicles could not drive within 2 kilometers (1.5 miles). Since those efforts have failed to save the Taj Majal's complexion, Indian officials have considered applying a cleansing mud pack to the monument's surface to draw out the dirt. As India industrializes, smog results, and the Taj Mahal's gleaming whiteness is only one casualty. Pollution has been blamed for a decrease in Indian rice harvests, which had soared during the 'Green Revolution' of the 1960s and 1970s. Haze and dust also appear to bring on the region's monsoon rains earlier than normal.
Distribution of Elements of Cosets of Small Subgroups and Applications
Bourgain, Jean; Shparlinski, Igor E
2011-01-01
We obtain a series of estimates on the number of small integers and small order Farey fractions which belong to a given coset of a subgroup of order $t$ of the group of units of the residue ring modulo a prime $p$, in the case when $t$ is small compared to $p$. We give two applications of these results: to the simultaneous distribution of two high degree monomials $x^{k_1}$ and $x^{k_2}$ modulo $p$ and to a question of J.~Holden and P.~Moree on fixed points of the discrete logarithm.
Distribution on elements of cosets of small subgroups and applications
Bourgain, Jean; Shparlinski, Igor
2011-01-01
We obtain a series of estimates on the number of small integers and small order Farey fractions which belong to a given coset of a subgroup of order $t$ of the group of units of the residue ring modulo a prime $p$, in the case when $t$ is small compared to $p$. We give two applications of these results: to the simultaneous distribution of two high degree monomials $x^{k_1}$ and $x^{k_2}$ modulo $p$ and to a question of J.Holden and P.Moree on fixed points of the discrete logarithm.
Saxena, Beenam; Sharma, Shiv
2014-01-01
Objective: The present study was carried out to evaluate the toxic effect of blend of some food colors on Swiss albino rats. Materials and Methods: A blend (1:1:1) of sunset yellow, metanil yellow and tartrazine showed additive effects on serological parameters which indicate that addition of these dye together in food stuff may give rise to more toxic effects than are produced by each dye individually. Animals were divided into four groups (I, II, III, and IV). First group was treated as con...
Upgrading the safety toolkit: Initiatives of the accident analysis subgroup
O' Kula, K.R.; Chung, D.Y.
1999-07-01
Since its inception, the Accident Analysis Subgroup (AAS) of the Energy Facility Contractors Group (EFCOG) has been a leading organization promoting development and application of appropriate methodologies for safety analysis of US Department of Energy (DOE) installations. The AAS, one of seven chartered by the EFCOG Safety Analysis Working Group, has performed an oversight function and provided direction to several technical groups. These efforts have been instrumental toward formal evaluation of computer models, improving the pedigree on high-use computer models, and development of the user-friendly Accident Analysis Guidebook (AAG). All of these improvements have improved the analytical toolkit for best complying with DOE orders and standards shaping safety analysis reports (SARs) and related documentation. Major support for these objectives has been through DOE/DP-45.
Genomic compositions and phylogenetic analysis of Shigella boydii subgroup
无
2006-01-01
Comparative Genomic Hybridization (CGH) microarray analysis was used to compare the genomic compositions of all eighteen Shigella boydii serotype representative strains. The results indicated the genomic "backbone" of this subgroup contained 2552 ORFs homologous to nonpathogenic E. coli K12. Compared with the genome of K12199 ORFs were found to be absent in all S. boydii serotype representatives, including mainly outer membrane protein genes and O-antigen biosynthesis genes. Yet the specific ORFs of S. boydii subgroup contained basically bacteriophage genes and the function unknown (FUN) genes. Some iron metabolism, transport and type II secretion system related genes were found in most representative strains. According to the CGH phylogenetic analysis, the eighteen S. boydii serotype representatives were divided into four groups, in which serotype C13 strain was remarkably distinguished from the other serotype strains. This grouping result corresponded to the distribution of some metabolism related genes. Furthermore, the analysis of genome backbone genes, specific genes, and the phylogenetic trees allowed us to discover the evolution laws of S. boydii and to find out important clues to pathogenesis research, vaccination and the therapeutic medicine development.
Myasthenia gravis: subgroup classification and therapeutic strategies.
Gilhus, Nils Erik; Verschuuren, Jan J
2015-10-01
Myasthenia gravis is an autoimmune disease that is characterised by muscle weakness and fatigue, is B-cell mediated, and is associated with antibodies directed against the acetylcholine receptor, muscle-specific kinase (MUSK), lipoprotein-related protein 4 (LRP4), or agrin in the postsynaptic membrane at the neuromuscular junction. Patients with myasthenia gravis should be classified into subgroups to help with therapeutic decisions and prognosis. Subgroups based on serum antibodies and clinical features include early-onset, late-onset, thymoma, MUSK, LRP4, antibody-negative, and ocular forms of myasthenia gravis. Agrin-associated myasthenia gravis might emerge as a new entity. The prognosis is good with optimum symptomatic, immunosuppressive, and supportive treatment. Pyridostigmine is the preferred symptomatic treatment, and for patients who do not adequately respond to symptomatic therapy, corticosteroids, azathioprine, and thymectomy are first-line immunosuppressive treatments. Additional immunomodulatory drugs are emerging, but therapeutic decisions are hampered by the scarcity of controlled studies. Long-term drug treatment is essential for most patients and must be tailored to the particular form of myasthenia gravis.
Subgrouping the autism "spectrum": reflections on DSM-5.
Meng-Chuan Lai
Full Text Available DSM-5 has moved autism from the level of subgroups ("apples and oranges" to the prototypical level ("fruit". But making progress in research, and ultimately improving clinical practice, will require identifying subgroups within the autism spectrum.
1995-01-01
THE Yellow River is the Mother River of China. In the hearts of the Chinese people, it is not just an ancient river measuring 4,845 kilometers long that passes through nine provinces and regions, but also a symbol. The poets say that the waterway is the image of ancient China. Thephilosophers say the river is the shadow of a dragon. The river
Larsen, John Christian; Nørby, Karin Kristiane; Beltoft, Vibe Meister
. The Panel therefore concluded that further data are required in order to clarify the genotoxic potential of this subgroup. The Panel considers the Comet assay with [FL-no: 05.095] as test material and performed on liver, blood and first site of contact, as a preferred option to further investigate...
Team negotiation: social, epistemic, economic, and psychological consequences of subgroup conflict.
Halevy, Nir
2008-12-01
Large collectives (e.g., organizations, political parties, nations) are seldom unitary players. Rather, they consist of different subgroups that often have conflicting interests. Nonetheless, negotiation research consistently regards negotiating teams, who represent these collectives, as monolithic parties with uniform interests. This article integrates concepts from social psychology, management, political science, and behavioral game theory to explore the effects of subgroup conflict on team negotiation. Specifically, the present research introduced a conflict of interests within negotiating teams and investigated how this internal conflict affects the outcome of the negotiation between teams. An experiment with 80 four-person teams found that conflict between subgroups had a detrimental effect on the performance of negotiating teams. This research also employed a recent model of motivated information processing in groups to investigate possible processes underlying the effect of subgroup conflict on team negotiation.
Ramos, Vera; Canta, Guilherme; de Castro, Filipa; Leal, Isabel
2014-08-01
Research suggests that borderline personality disorder (BPD) can be diagnosed in adolescents and is marked by considerable heterogeneity. This study aimed to identify personality features characterizing adolescents with BPD and possible meaningful patterns of heterogeneity that could lead to personality subgroups. The authors analyzed data on 60 adolescents, ages 15 to 18 years, who met DSM criteria for a BPD diagnosis. The authors used latent class analysis (LCA) to identify subgroups based on the personality pattern scales from the Millon Adolescent Clinical Inventory (MACI). LCA indicated that the best-fitting solution was a two-class model, identifying two discrete subgroups of BPD adolescents that were described as internalizing and externalizing. The subgroups were then compared on clinical and sociodemographic variables, measures of personality dimensions, DSM BPD criteria, and perception of attachment styles. Adolescents with a BPD diagnosis constitute a heterogeneous group and vary meaningfully on personality features that can have clinical implications for treatment.
78 FR 35956 - Utah Resource Advisory Council Subgroup Conference Call
2013-06-14
... Bureau of Land Management Utah Resource Advisory Council Subgroup Conference Call AGENCY: Bureau of Land Management, Interior. ACTION: Conference Call. SUMMARY: In accordance with the Federal Land Policy and... Advisory Council (RAC) Subgroup will host a conference call. DATES: The Utah RAC Subgroup will host...
Identifying Subgroups among Hardcore Smokers: a Latent Profile Approach
Bommelé, J.; Kleinjan, M.; Schoenmakers, T.M.; Eijnden, R. van den; Mheen, D. van de
2015-01-01
Introduction: Hardcore smokers are smokers who have little to no intention to quit. Previous research suggests that there are distinct subgroups among hardcore smokers and that these subgroups vary in the perceived pros and cons of smoking and quitting. Identifying these subgroups could help to deve
Application of the Subgroup Decomposition Method (SDM for Reactor Simulation
Roskoff Nathan
2016-01-01
Full Text Available The performance of the TITAN-SDM algorithm for solving a reactor pressure vessel dosimetry problem is evaluated. Douglass and Rahnema recently developed the he subgroup decomposition method (SDM; a methodology which directly couples a consistent coarse-group transport calculation with a set of “decomposition sweeps” to provide a fine-group flux spectrum. The SDM has been implemented into the TITAN three-dimensional transport code and has been shown to accurately solve core criticality problems while significantly reducing computation time. This paper addresses the use of SDM for fixed-source problems. The VENUS-2 dosimetry benchmark problem is selected with an emphasis on fast neutron analysis; therefore, material cross sections are generated from the BUGLE-96 library considering neutron energies greater than 0.1 MeV. The accuracy and efficiency of TITAN-SDM is evaluated by comparison with a standard TITAN multigroup calculation.
Planar Algebra of the Subgroup-Subfactor
Ved Prakash Gupta
2008-11-01
We give an identification between the planar algebra of the subgroup-subfactor $R \\rtimes H \\subset R \\rtimes G$ and the -invariant planar subalgebra of the planar algebra of the bipartite graph $\\star_n$, where $n=[G:H]$. The crucial step in this identification is an exhibition of a model for the basic construction tower, and thereafter of the standard invariant of $R \\rtimes H \\subset R \\rtimes G$ in terms of operator matrices. We also obtain an identification between the planar algebra of the fixed algebra subfactor $R^G \\subset R^H$ and the -invariant planar subalgebra of the planar algebra of the `flip’ of $\\star_n$.
Planar Algebra of the Subgroup-Subfactor
Gupta, Ved Prakash
2008-01-01
We give an identification between the planar algebra of the subgroup-subfactor $R \\rtimes H \\subset R \\rtimes G$ and the $G$-invariant planar subalgebra of the planar algebra of the bipartite graph $\\star_n$, where $n = [G : H]$. The crucial step in this identification is an exhibition of a model for the basic construction tower, and thereafter of the standard invariant, of $R \\rtimes H \\subset R \\rtimes G$ in terms of operator matrices. We also obtain an identification between the planar algebra of the fixed algebra subfactor $R^G \\subset R^H$ and the $G$-invariant planar subalgebra of the planar algebra of the `flip' of $\\star_n $.
Oude Elberink, Joanne N G; De Monchy, Jan G R; Van Der Heide, Sicco; Guyatt, Gordon H; Dubois, Anthony E J
2002-07-01
Venom immunotherapy (VIT) is effective in preventing anaphylactic reactions after insect stings. The effect of VIT on health-related quality of life (HRQL) was studied to evaluate whether this treatment is of importance to patients. We compared HRQL outcomes measured with a disease-specific instrument (Vespid Allergy Quality-of-Life Questionnaire [VQLQ]) in patients allergic to yellow jacket venom treated with VIT or with an adrenalin self-administration device (EpiPen) in an open-label, randomized, controlled trial. Consenting patients were block randomized to either VIT or EpiPen. Patients received uniform, standardized information, which specified the risk of their condition and the risks and benefits of both treatment options. HRQL measures took place before and after 1 year of treatment with VIT or EpiPen. Seventy-four patients agreed to be randomized, of whom 36 received VIT and 38 an EpiPen. The mean change in VQLQ score in the group randomized to VIT was 1.07 (95% CI, 0.68-1.46), and this improvement was statistically significant (P jacket venom in all subgroups studied. Of every 3 patients treated with VIT, 2 patients experience an important improvement in their quality of life.
Presence and characterization of Zucchini yellow mosaic virus in watermelon in Serbia
Vučurović Ana
2012-01-01
Full Text Available The presence of Zucchini yellow mosaic virus (ZYMV in two out of seven watermelon production localities in Serbia during 2011 was investigated by analyzing leaves sampled from symptomatic and asymptomatic watermelon plants and utilizing DAS-ELISA test. In the locality of Gornji Tavankut, ZYMV was detected in 23.08% of tested plants in single infections, and in the locality of Silbas it was detected in 35.29% of tested plants in mixed infections with Cucumber mosaic virus and Alfalfa mosaic virus. ZYMV was successfully mechanically transmitted from naturally infected watermelon plants to Cucurbita pepo 'Ezra F1'. Molecular detection was performed by RT-PCR and amplification of part of the gene for nuclear inclusions, gene of coat protein and part of 3' non-coding region, which confirmed the identification of the ZYMV isolates. Phylogenetic analysis revealed grouping of the isolate originating from watermelon with other isolates from Serbia and Central Europe within A-I subgroup. Analysis of amino acid sequences of the N terminal end of the CP gene revealed that isolate 550-11 belongs to the Central European branch.
Becker, Heiko; Suciu, Stefan; Rüter, Björn Hans; Platzbecker, Uwe; Giagounidis, Aristoteles; Selleslag, Dominik; Labar, Boris; Germing, Ulrich; Salih, Helmut R; Muus, Petra; Pflüger, Karl-Heinz; Hagemeijer, Anne; Schaefer, Hans-Eckart; Fiaccadori, Valeria; Baron, Frédéric; Ganser, Arnold; Aul, Carlo; de Witte, Theo; Wijermans, Pierre W; Lübbert, Michael
2015-12-01
In the European Organisation for Research and Treatment of Cancer (EORTC)/GMDSSG phase III trial 06011, we compared decitabine (15 mg/m(2) every 8 h for 3 days) with best supportive care (BSC) in patients ≥60 years with myelodysplastic syndromes (MDS) by French-American-British (FAB) criteria. Here, we reinvestigate trial 06011 for the activity and efficacy specifically in patients with refractory anemia with excess blasts in transformation (RAEBt). Response rates in the decitabine arm (N = 40) were as follows: complete or partial remission, 15 %; hematologic improvement, 15 %; resistant disease, 30 %. RAEBt patients in the decitabine arm had longer progression-free survival (PFS; hazard ratio (HR) 0.30, 95 % confidence interval (CI) 0.18-0.51; median, 6.2 vs 2.8 months) and overall survival (OS; HR 0.68, 95 % CI 0.42-1.11; median, 8.0 vs 6.0 months) than in the BSC arm (N = 35). Censoring at allogeneic hematopoietic stem cell transplantation, the OS difference between the treatment groups increased, particularly among patients aged 60-74 years (HR 0.48, 95 % CI 0.26-0.89). After regrouping the study cohort according to World Health Organization (WHO) criteria, patients with acute myeloid leukemia (AML) (i.e., ≥20 % blasts) in the decitabine arm (N = 27) also had longer PFS than in the BSC arm (N = 23) (HR 0.46, 95 % CI 0.26-0.83; median, 6.2 vs 2.8 months). In conclusion, 3-day decitabine displays clinical activity and efficacy in MDS and/or AML with 5-30 % blood or 20-30 % marrow blasts.
Dong, Xuan; Zhao, Peng; Li, Weihua; Chang, Shuang; Li, Jianliang; Li, Yang; Ju, Sidi; Sun, Peng; Meng, Fanfeng; Liu, Juan; Cui, Zhizhong
2015-04-01
The diagnosis of avian leukosis virus subgroup J (ALV-J) infection in Chinese Partridge Shank chickens was confirmed by necropsy, histopathological examinations, antibody tests, viral isolation, immunofluorescence assays, and sequence analysis. Myelocytoma, myeloma, and fibrosarcoma were simultaneously found in Partridge Shank flock with ALV-J infection. Sequence analysis of the env genes of ALV-J demonstrated that both gp85 and gp37 were highly homologous among the three strains from local chickens of those among ALV-J strains isolated from white meat-type chickens. The phylogenetic trees indicated that the three strains isolated in this study were closely related to reference strains isolated in so-called Chinese yellow chickens and some strains isolated from white meat-type chickens, both from the USA and China. The observed ALV-J infection was the first report on Partridge Shank chickens, and myelocytoma, myeloma, and fibrosarcoma were found at the same time in this batch of local chickens.
Kabat, Halla; Tunkle, Leo; Lee, Inhan
2016-01-01
previously, our result is the first to propose ceRNA as one of its underlying mechanisms. Furthermore, since MET amplification was seen in the case of resistance to EGFR-targeted therapy, the EGFR-MET up and miR-133b down subgroup may fall into the drug non-response group and thus preclude EGFR target therapy.
Synthesis and characterization of yellow water-borne polyurethane using a diol colorant as extender
无
2010-01-01
A novel and facile method toward a series of yellow water-borne polyurethane was developed by using an intrinsically colored diol in this paper.The yellow aqueous dispersion PCLD-HENA-PU was synthesized based on isophorone diisocyanate(IPDI), polycaprolactonediol(PCLD) and 2,2-dimethylol propionic acid(DMPA) using a yellow diol N,N-bis(2-hydroxyethyl)-4-nitroaniline (HENA) as a chain extender.Due to the complete reaction of OH group in colorant HENA with NCO group in diisocyanate,a series of stable yello...
Quantum subgroups of the Haagerup fusion categories
Grossman, Pinhas
2011-01-01
We answer three related questions concerning the Haagerup subfactor and its even parts, the Haagerup fusion categories. Namely we find all simple module categories over each of the Haagerup fusion categories (in other words, we find the `"quantum subgroups" in the sense of Ocneanu), we find all subfactors whose principal even part is one of the Haagerup fusion categories, and we compute the Brauer-Picard groupoid of Morita equivalences of the Haagerup fusion categories. In addition to the two even parts of the Haagerup subfactor, there is exactly one more fusion category which is Morita equivalent to each of them. This third fusion category has six simple objects and the same fusion rules as one of the even parts of the Haagerup subfactor, but has not previously appeared in the literature. We also find the full lattice of intermediate subfactors for every subfactor whose even part is one of these three fusion categories, and we discuss how our results generalize to Izumi subfactors.
Working group report: Collider and flavour physics
Debajyoti Choudhury; Asesh K Datta; Anirban Kundu
2009-01-01
The activities of the working group took place under two broad subgroups: Collider Physics subgroup and Flavour Physics subgroup. Reports on some of the projects undertaken are included. Also, some of the leading discussions organized by the working group are summarized.
M.L. Sánchez
2006-06-01
Full Text Available En la ciudad de Neuquén y alrededores afloran depósitos del Cretácico superior asignados al Subgrupo Río Colorado. La presente contribución da a conocer los resultados del análisis sedimentológico y paleoambiental de las Formaciones Bajo de la Carpa (Santoniano y Anacleto (Campaniano inferior. Los estudios llevados a cabo permitieron definir cuatro litofacies conglomerádicas, nueve de areniscas y dos pelíticas, que fueron agrupadas en nueve asociaciones de litofacies, dos de ellas de origen eólico y siete fluviales. La Formación Bajo de la Carpa está representada en la base por un sistema fluvial efímero, y en el techo por depósitos de interacción fluvio- eólica. Los depósitos fluviales corresponden a flujos canalizados durante episodios de máxima descarga. Luego se identifica un campo de dunas transversales, afectado en el subambiente de interduna por corrientes fluviales efímeras, y dunas parabólicas producto de la removilización del sistema eólico infrayacente, asociadas con depósitos de flujos efímeros en manto. La extensión y geometría de los campos de dunas respondieron a variaciones climáticas de corto término, interferencia del sistema fluvial, oscilaciones del nivel freático, bajo suministro y/o disponibilidad de sedimentos y factores tectónicos. La Formación Anacleto presenta en su base sistemas fluviales de baja sinuosidad, alta energía y rápida agradación, controlados por un bajo espacio de acomodación y condiciones climáticas con marcada estacionalidad. Hacia el tope se identifica un sistema fluvial anastomosado que refleja variaciones climáticas y aumento de la tasa de subsidencia acompañada de un lento ascenso del nivel de base relacionado con la ingresión atlántica maastrichtiana.Upper Cretaceous deposits included in Río Colorado Subgroup crop out in Neuquén city and surrounding areas. This work shows the results of the sedimentogical and paleoenvironmental analysis of Bajo de la Carpa
Elabd, Hiam; Wang, Han-Ping; Shaheen, Adel; Yao, Hong; Abbass, Amany
2016-07-01
The current work assessed the potential immunomodulatory and growth-promoting effects of Astragalus membranaceus (AM) and Glycyrrhiza glabra (liquorice) in Yellow perch (Perca flavescens). In this regard, fish with an average weight of 31 ± 1.0 g were divided into five groups, and fed daily with an additive-free basal diet (control); 1, 2, and 3% (w/w) Glycyrrhiza glabra, and the fifth diet was incorporated with a combination of 1% G. glabra-AM for a four-week period. Immunological, biochemical and growth parameters were measured; and sub-groups of fish were exposed to 1-week starvation. The results showed that incorporating AM and liquorice in the diet significantly improved Immunological [superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), Lipid peroxidase (LPx) and lysozyme activities], biochemical [Aspartate Aminotransferase (AST) and Alanine Transaminase (ALT) activities; and glucose and cortisol concentrations] and growth performance parameters [body mass gain (BMG), specific growth rate (SGR), length, condition factor (K) and feed conversion ratio (FCR)]. In addition, markedly up-regulated the expression of related genes [Insulin-Like Growth Factor-1 (IGF-1), Serum amyloid A (SAA), Complement Component C3 (CCC3), Alpha 2 Macroglobulin (A2M), SOD and GPx] in treated fish groups compared to the control. Conclusively, feeding AM and liquorice diets significantly increased (P < 0.05) growth performance, antioxidant and immune response profiles throughout the entire experiment, suggesting their beneficial rule as natural anti-stress agents.
Coutts, B A; Kehoe, M A; Webster, C G; Wylie, S J; Jones, R A C
2011-12-01
Between 2006 and 2010, 5324 samples from at least 34 weed, two cultivated legume and 11 native species were collected from three cucurbit-growing areas in tropical or subtropical Western Australia. Two new alternative hosts of zucchini yellow mosaic virus (ZYMV) were identified, the Australian native cucurbit Cucumis maderaspatanus, and the naturalised legume species Rhyncosia minima. Low-level (0.7%) seed transmission of ZYMV was found in seedlings grown from seed collected from zucchini (Cucurbita pepo) fruit infected with isolate Cvn-1. Seed transmission was absent in >9500 pumpkin (C. maxima and C. moschata) seedlings from fruit infected with isolate Knx-1. Leaf samples from symptomatic cucurbit plants collected from fields in five cucurbit-growing areas in four Australian states were tested for the presence of ZYMV. When 42 complete coat protein (CP) nucleotide (nt) sequences from the new ZYMV isolates obtained were compared to those of 101 complete CP nt sequences from five other continents, phylogenetic analysis of the 143 ZYMV sequences revealed three distinct groups (A, B and C), with four subgroups in A (I-IV) and two in B (I-II). The new Australian sequences grouped according to collection location, fitting within A-I, A-II and B-II. The 16 new sequences from one isolated location in tropical northern Western Australia all grouped into subgroup B-II, which contained no other isolates. In contrast, the three sequences from the Northern Territory fitted into A-II with 94.6-99.0% nt identities with isolates from the United States, Iran, China and Japan. The 23 new sequences from the central west coast and two east coast locations all fitted into A-I, with 95.9-98.9% nt identities to sequences from Europe and Japan. These findings suggest that (i) there have been at least three separate ZYMV introductions into Australia and (ii) there are few changes to local isolate CP sequences following their establishment in remote growing areas. Isolates from A-I and B
Report of the Production and Delivery Subgroup
Glass, R; Zalesky, R
2004-11-01
The Production and Delivery Subgroup was tasked with evaluating the various options that could be used for hydrogen production and delivery in terms of availability/industry readiness, technical and economic barriers, and environmental considerations. Hydrogen can be produced using a variety of feedstocks and conversion technologies. The feedstock options include water, natural gas, coal, petroleum, methanol, ethanol, biomass, and organic waste streams. Ultimately, using these domestic resources we will be able to produce all the hydrogen we will need for the complete conversion of our transportation infrastructure. The various conversion technologies include electrolysis, reforming (principally of natural gas, but also ethanol and methanol), photobiological and photoelectrochemical, biofermentation, pyrolysis and gasification of biomass and coal, high temperature thermochemical, and catalytic membranes. All of these production technologies are being actively researched by DOE's Office of Hydrogen, Fuel Cells and Infrastructure Technologies (HFCIT); and other offices within DOE support work that complements the HFCIT Program activities. In addition, private industry is also dedicating significant resources to these efforts. In establishing the California Hydrogen Highway Network (CA H2 Net) we must utilize both distributed (that is, hydrogen that is produced at the point of use) as well as centralized production of hydrogen. Because of technical and economic barriers, most of the technologies for hydrogen production listed above will not become practical for either mode of hydrogen production in large quantities until at least the 2015-2030 timeframe. In the near term, that is, the transitional period between now and 2010 when we will establish a widely available hydrogen fueling infrastructure in California, the distributed production options of reforming and electrolysis will play the dominant role. In addition, production of hydrogen at centralized plants
The Scientific Challenges of Yellow River Study
Liu Xiaoyan; Sun Yangbo
2005-01-01
@@ The Yellow River is famous for its complex and unique physical conditions which give great challenges to the river management. Based on the study and analysis of the existing problems and research progress, this paper indicated that the most significant challenges of Yellow River studies are: long term hydrological and morphological changes; the optimized hydrology and sediment conditions to maintain the healthy life of the River; and simulation of Yellow River through mathematical model and physical models.
Titanium exposure and yellow nail syndrome
Ali Ataya
2015-01-01
Full Text Available Yellow nail syndrome is a rare disease of unclear etiology. We describe a patient who develops yellow nail syndrome, with primary nail and sinus manifestations, shortly after amalgam dental implants. A study of the patient's nail shedding showed elevated nail titanium levels. The patient had her dental implants removed and had complete resolution of her sinus symptoms with no change in her nail findings. Since the patient's nail findings did not resolve we do not believe titanium exposure is a cause of her yellow nail syndrome but perhaps a possible relationship exists between titanium exposure and yellow nail syndrome that requires further studies.
Ge, Jiachun; Dong, Zhangji; Li, Jingyun; Xu, Zhiqiang; Song, Wei; Bao, Jie; Liang, Dong; Li, Junbo; Li, Kui; Jia, Wenshuang; Zhao, Muzi; Cai, Yongxiang; Yang, Jiaxin; Pan, Jianlin; Zhao, Qingshun
2012-10-01
Yellow catfish (Pelteobagrus fulvidraco Richardson) is one of the most important freshwater farmed species in China. However, its small size and slow growth rate limit its commercial value. Because genetic engineering has been a powerful tool to develop and improve fish traits for aquaculture, we performed transgenic research on yellow catfish in order to increase its size and growth rate. Performing PCR with degenerate primers, we cloned a genomic fragment comprising 5'-flanking sequence upstream of the initiation codon of β-actin gene in yellow catfish. The sequence is 1,017 bp long, containing the core sequence of proximal promoter including CAAT box, CArG motif and TATA box. Microinjecting the transgene construct Tg(beta-actin:eYFP) of the proximal promoter fused to enhanced yellow fluorescent protein (eYFP) reporter gene into zebrafish and yellow catfish embryos, we found the promoter could drive the reporter to express transiently in both embryos at early development. Screening the offspring of five transgenic zebrafish founders developed from the embryos microinjected with Tg(ycbeta-actin:mCherry) or 19 yellow catfish founders developed from the embryos microinjected with Tg(beta-actin:eYFP), we obtained three lines of transgenic zebrafish and one transgenic yellow catfish, respectively. Analyzing the expression patterns of the reporter genes in transgenic zebrafish (Tg(ycbeta-actin:mCherry)nju8/+) and transgenic yellow catfish (Tg(beta-actin:eYFP)nju11/+), we found the reporters were broadly expressed in both animals. In summary, we have established a platform to make transgenic yellow catfish using the proximal promoter of its own β-actin gene. The results will help us to create transgenic yellow catfish using "all yellow catfish" transgene constructs.
Yang, Rongchang; Brice, Belinda; Jian, Fuchun; Ryan, Una
2016-04-01
A new Isospora (Apicomplexa:Eimeriidae) species is described from a single yellow-throated miner bird (Manorina flavigula) (subspecies M. f. wayensis) in Western Australia. Sporulated oocysts (n = 32) of this isolate are spherical to subspherical, 22.8 (20.3-23.8) × 18.3 (17.7-18.7) μm, with a shape index (length/width) of 1.25 (1.2-1.3); and a smooth and bilayered oocyst wall, 1.3 μm thick (outer layer 0.9 μm, inner 0.4 μm). A polar granule is present, but the micropyle and oocyst residuum are absent. The sporocysts are lemon-shaped, 15.5 (14.6-15.8) × 9.5 (9.5-10.2) μm, with a shape index of 1.6. Stieda and substieda bodies are present, the Stieda body being knob-like and the substieda body being subspherical-shaped. A sporocyst residuum is present and composed of numerous granules of different size scattered among the sporozoites, a spheroid or subspheroid refractile body is present in the sporozoite. Morphologically, the oocysts from this isolate are different from those of all known valid Isospora spp. Molecular analysis was conducted at 3 loci; the 18S and 28S ribosomal RNA and the mitochondrial cytochrome oxidase (COI) gene. At the 18S locus, this new isolate exhibited 99.2% similarity to Isospora gryphoni and three other Isospora spp. Further analysis of a subgroup of 300 bp long 18S sequences (8), including Isospora anthochaerae was conducted. This new isolate grouped in a clade with I. anthochaerae and exhibited 99.3% similarity. At the 28S locus, this new isolate grouped with I. anthochaerae with which it shared 99.1% similarity. At the COI locus, this new isolate exhibited 96.8% similarity to Isospora sp. JCI-2015 from a spectacled warbler (Sylvia conspicillata) in Spain. Further analysis from a subgroup of shorter COI sequences (n = 13) was performed and this new isolate exhibited 99.1% similarity to I. anthochaerae. Based on morphological and molecular data, this isolate is a new species of Isospora, which is named Isospora manorinae n. sp
The rationality problem for finite subgroups of GL_4(Q)
Kang, Ming-chang
2010-01-01
Let $G$ be a finite subgroup of $GL_4(\\bm{Q})$. The group $G$ induces an action on $\\bm{Q}(x_1,x_2,x_3,x_4)$, the rational function field of four variables over $\\bm{Q}$. Theorem. The fixed subfield $\\bm{Q}(x_1,x_2,x_3,x_4)^G:=\\{f\\in\\bm{Q}(x_1,x_2,x_3,x_4):\\sigma \\cdot f=f$ for any $\\sigma\\in G\\}$ is rational (i.e.\\ purely transcendental) over $\\bm{Q}$, except for two groups which are images of faithful representations of $C_8$ and $C_3\\rtimes C_8$ into $GL_4(\\bm{Q})$ (both fixed fields for these two exceptional cases are not rational over $\\bm{Q}$). There are precisely 227 such groups in $GL_4(\\bm{Q})$ up to conjugation; the answers to the rationality problem for most of them were proved by Kitayama and Yamasaki \\cite{KY} except for four cases. We solve these four cases left unsettled by Kitayama and Yamasaki; thus the whole problem is solved completely.
Weinberg Angle Derivation from Discrete Subgroups of SU(2 and All That
Potter F.
2015-01-01
Full Text Available The Weinberg angle W of the Standard Model of leptons and quarks is derived from specific discrete (i.e., finite subgroups of the electroweak local gauge group SU(2 L U(1 Y . In addition, the cancellation of the triangle anomaly is achieved even when there are four quark families and three lepton families!
Affine spherical homogeneous spaces with good quotient by a maximal unipotent subgroup
Avdeev, Roman S [M. V. Lomonosov Moscow State University, Faculty of Mechanics and Mathematics, Moscow (Russian Federation)
2012-11-30
For an affine spherical homogeneous space G/H of a connected semisimple algebraic group G, we consider the factorization morphism by the action on G/H of a maximal unipotent subgroup of G. We prove that this morphism is equidimensional if and only if the weight semigroup of G/H satisfies a simple condition. Bibliography: 16 titles.
Shin, Yoolim
2010-01-01
This study investigated psychosocial and friendship characteristics of Korean children who engaged in bully/victim subgroups among their peer groups. The participants were 605 elementary school students in Bucheon City, Korea. The participants completed a peer nomination inventory as well as loneliness and social anxiety scales. Friendship quality…
Preparation and Application on the Inactivated Bacterins of Yellow and White Scour of Piglets
Fan Jianhua; Hu Hui; Hu Yan; Xu Bu
2015-01-01
Pathogenic Escherichia coli strains were isolated from yellow and white scour samples in pig farms. The strains were used to make autologous inactivated bacterins,and the bacterins were applied to multiple infected farms. The results showed that in the group of inactivated bacterins,the infected piglet number was less,the course of disease was shorter and the symptoms was milder. The piglet E. coli inactivated bacterins could significantly reduced morbidity of yellow and white scour of piglets,the preventive effects of E. coli autologous inactivated bacterins against yellow and white scour of piglets were much better than that of genetically engineered vaccines.
Subgroup analysis of telehealthcare for patients with chronic obstructive pulmonary disease
Witt Udsen, Flemming; Lilholt, Pernille H.; Hejlesen, Ole K.
2017-01-01
severities were analyzed. Second, five additional subgroup analyses were conducted, focusing on differences in cost-effectiveness across a set of comorbidities, age-groups, genders, resource patterns (resource use in the social care sector prior to randomization), and delivery sites. All subgroups were...... investigated post hoc. In analyzing cost-effectiveness, two separate linear mixed-effects models with treatment-by-covariate interactions were applied: one for quality-adjusted life-year (QALY) gain and one for total healthcare and social sector costs. Probabilistic sensitivity analysis was used for each...
Choi, Seung-Kook; Yoon, Ju-Yeon; Choi, Gug-Seoun
2015-12-01
Surveys of yellowing viruses in plastic tunnels and in open field crops of melon (Cucumis melo cultivar catalupo), oriental melon (C. melo cultivar oriental melon), and cucumber (C. sativus) were carried out in two melon-growing areas in 2014, Korea. Severe yellowing symptoms on older leaves of melon and chlorotic spots on younger leaves of melon were observed in the plastic tunnels. The symptoms were widespread and included initial chlorotic lesions followed by yellowing of whole leaves and thickening of older leaves. RT-PCR analysis using total RNA extracted from diseased leaves did not show any synthesized products for four cucurbit-infecting viruses; Beet pseudo-yellows virus, Cucumber mosaic virus, Cucurbit yellows stunting disorder virus, and Melon necrotic spot virus. Virus identification using RT-PCR showed Cucurbit aphid-borne yellows Virus (CABYV) was largely distributed in melon, oriental melon and cucumber. This result was verified by aphid (Aphis gossypii) transmission of CABYV. The complete coat protein (CP) gene amplified from melon was cloned and sequenced. The CP gene nucleotide and the deduced amino acid sequence comparisons as well as phylogenetic tree analysis of CABYV CPs showed that the CABYV isolates were undivided into subgroups. Although the low incidence of CABYV in infections to cucurbit crops in this survey, CABYV may become an important treat for cucurbit crops in many different regions in Korea, suggesting that CABYV should be taken into account in disease control of cucurbit crops in Korea.
Seung-Kook Choi
2015-12-01
Full Text Available Surveys of yellowing viruses in plastic tunnels and in open field crops of melon (Cucumis melo cultivar catalupo, oriental melon (C. melo cultivar oriental melon, and cucumber (C. sativus were carried out in two melon-growing areas in 2014, Korea. Severe yellowing symptoms on older leaves of melon and chlorotic spots on younger leaves of melon were observed in the plastic tunnels. The symptoms were widespread and included initial chlorotic lesions followed by yellowing of whole leaves and thickening of older leaves. RT-PCR analysis using total RNA extracted from diseased leaves did not show any synthesized products for four cucurbit-infecting viruses; Beet pseudo-yellows virus, Cucumber mosaic virus, Cucurbit yellows stunting disorder virus, and Melon necrotic spot virus. Virus identification using RT-PCR showed Cucurbit aphid-borne yellows Virus (CABYV was largely distributed in melon, oriental melon and cucumber. This result was verified by aphid (Aphis gossypii transmission of CABYV. The complete coat protein (CP gene amplified from melon was cloned and sequenced. The CP gene nucleotide and the deduced amino acid sequence comparisons as well as phylogenetic tree analysis of CABYV CPs showed that the CABYV isolates were undivided into subgroups. Although the low incidence of CABYV in infections to cucurbit crops in this survey, CABYV may become an important treat for cucurbit crops in many different regions in Korea, suggesting that CABYV should be taken into account in disease control of cucurbit crops in Korea.
Identifying subgroups of patients using latent class analysis
Nielsen, Anne Mølgaard; Kent, Peter; Hestbæk, Lise
2017-01-01
BACKGROUND: Heterogeneity in patients with low back pain (LBP) is well recognised and different approaches to subgrouping have been proposed. Latent Class Analysis (LCA) is a statistical technique that is increasingly being used to identify subgroups based on patient characteristics. However, as ...
Working group report: Quantum chromodynamics
V Ravindra; Pankaj Agrawal; Rahul Basu; Satyaki Bhattacharya; J Blümlein; V Del Duca; R Harlander; D Kosower; Prakash Mathews; Anurag Tripathi
2006-11-01
This is the report of the subgroup QCD of Working Group-4 at WHEPP-9. We present the activities that had taken place in the subgroup and report some of the partial results arrived at following the discussion at the working group meetings.
Thoracic surgical implications of the yellow nail syndrome.
David, I; Crawford, F A; Hendrix, G H; Harley, R A; Tucker, T
1986-05-01
Idiopathic lymphedema associated with yellow discoloration of the nail beds constitutes the yellow nail syndrome. Pleural effusions and chronic sinusitis are also frequently present. This report describes a case of yellow nail syndrome in a 65-year-old woman.
Biostatistics primer: what a clinician ought to know: subgroup analyses.
Barraclough, Helen; Govindan, Ramaswamy
2010-05-01
Large randomized phase III prospective studies continue to redefine the standard of therapy in medical practice. Often when studies do not meet the primary endpoint, it is common to explore possible benefits in specific subgroups of patients. In addition, these analyses may also be done, even in the case of a positive trial to find subsets of patients where the therapy is especially effective or ineffective. These unplanned subgroup analyses are justified to maximize the information that can be obtained from a study and to generate new hypotheses. Unfortunately, however, they are too often overinterpreted or misused in the hope of resurrecting a failed study. It is important to distinguish these overinterpreted, misused, and unplanned subgroup analyses from those prespecified and well-designed subgroup analyses. This overview provides a practical guide to the interpretation of subgroup analyses.
Beltoft, Vibe Meister; Nørby, Karin Kristiane
genotoxicity studies on p-mentha-1,8-dien-7-al [FL-no: 05.117], the representative substance for FGE.19 subgroup 2.2. This substance was tested in vivo in a combined micronucleus assay in bone marrow and Comet assay in liver and duodenum. It did not induce any increase in micronucleated polychromatic...... erythrocytes of the bone marrow of male rats in the micronucleus test and it did not induce DNA damage in duodenum of the same animals as analysed by the Comet assay. The Comet assay performed in liver shows a positive result and therefore the Panel concluded that p-mentha-1,8-dien-7-al [FL-no: 05...
Larsen, John Christian; Nørby, Karin Kristiane; Beltoft, Vibe Meister;
The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs...... genotoxic effects in germ cells, which theoretically may result in reduced reproductive capacity or in inheritable genetic damage. Reduced reproductive capacity and inheritable genetic damage are toxicological endpoints which differ from carcinogenicity and therefore, the negative results...... that the representative substance for subgroup 4.4b, 4-hydroxy-2,5-dimethylfuran-3(2H)-one [FL-no: 13.010], is unable to induce adverse effects both on male rat reproductive capacity and dominant lethality. On this basis, the Panel concludes that there is no concern for this substance to induce heritable genetic damage...
The status of Cucumber vein yellowing virus in Iran
Kaveh BANANEJ
2014-09-01
Full Text Available Yellowing symptoms of greenhouse- and open field-grown cucurbit crops are becoming increasingly important in many cucurbit growing regions of the world, and particularly in Iran. A survey was conducted from 2011 to 2012 in eight major cucurbit growing regions in Iran. Yellowing and specifically vein clearing symptoms were observed in many cucumber plants grown in greenhouses and open fields, suggesting the presence of Cucumber vein yellowing virus (CVYV, genus Ipomovirus, family Potyviridae. The identification of CVYV was carried out with a specific triple-antibody sandwich enzyme-linked immunosorbent assay (TAS-ELISA and reverse transcription (RT-PCR. CVYV was detected in 42% of the collected samples, in all surveyed provinces, except Bushehr. CVYV was also detected in melon and cucumber crops grown in open fields. These results indicate that CVYV is widely distributed on these two cucurbit species in the major cucumber growing areas of Iran. CVYV positive samples were also tested, using DAS-ELISA, for the presence of Cucurbit chlorotic yellows virus (CCYV and Cucurbit yellow stunting disorder virus (CYSDV, two criniviruses reported previously to occur in Iran. Double or triple infections of CCYV and CYSDV occurred in 49 of 166 of the CVYV-infected plants. The CVYV and CCYV combined infections were more prevalent than CVYV and CYSDV combined infections. TAS-ELISA positive samples were used to mechanically inoculate healthy cucumber plants, and mild vein yellowing was observed on the inoculated leaves. Identical symptoms were also observed on whitefly inoculated healthy cucumber plants. The presence of CVYV in mechanically and whitefly inoculated plants was confirmed by TAS-ELISA and RT-PCR. Sequence analysis revealed that the Iranian isolate of CVYV was more closely related to Spanish isolates than to isolates from Jordan. Phylogenetic analysis showed that CVYV isolates can be divided into two phylogenetic groups (I and II. Despite the close
Kalavi, F N; Muroki, N M; Omwega, A M; Mwadime, R K
1996-07-01
The diet for 117 protein-energy-malnourished children admitted into the Mbooni Family Life Training Centre between November 1992 and March 1993, was supplemented with either tempe-yellow maize porridge (TYMP) or milk-yellow maize porridge (MYMP). Fifty-six malnourished children had their diet supplemented with TYMP. Another group of 61 children had theirs supplemented with MYMP. The growth rate (weight gain), duration of diarrhoeal episodes and rehabilitation period for each child was recorded and a comparison made between the two dietary groups. The TYMP group achieved a significantly (p 0.05) lower than that for the MYMP group which was 20 days. Furthermore, the cost of supplementing the diet for each child with the tempe-yellow maize porridge (KSh. 1625) was approximately 25% lower than that of supplementing it with milk-yellow maize porridge which was KSh. 2060. These results suggest that it may be more beneficial in terms of duration of both diarrhoeal episodes and rehabilitation period and overall institutional cost if malnourished children's diets are supplemented with tempe-yellow maize porridge.
Eirikstoft, Heidi; Kongsted, Alice
2014-02-01
Sub-grouping of low back pain (LBP) is believed to improve prediction of prognosis and treatment effects. The objectives of this study were: (1) to examine whether chiropractic patients could be sub-grouped according to an existing pathoanatomically-based classification system, (2) to describe patient characteristics within each subgroup, and (3) to determine the proportion of patients in whom clinicians considered the classification to be unchanged after approximately 10 days. A cohort of 923 LBP patients was included during their first consultation. Patients completed an extensive questionnaire and were examined according to a standardised protocol. Based on the clinical examination, patients were classified into diagnostic subgroups. After approximately 10 days, chiropractors reported whether they considered the subgroup had changed. The most frequent subgroups were reducible and partly reducible disc syndromes followed by facet joint pain, dysfunction and sacroiliac (SI)-joint pain. Classification was inconclusive in 5% of the patients. Differences in pain, activity limitation, and psychological factors were small across subgroups. Within 10 days, 82% were reported to belong to the same subgroup as at the first visit. In conclusion, LBP patients could be classified according to a standardised protocol, and chiropractors considered most patient classifications to be unchanged within 10 days. Differences in patient characteristics between subgroups were very small, and the clinical relevance of the classification system should be investigated by testing its value as a prognostic factor or a treatment effect modifier. It is recommended that this classification system be combined with psychological and social factors if it is to be useful.
[Pleuritis in yellow nail syndrome].
Kossakowski, C A; Schmiegelow, P; Müller, K-M
2012-03-01
A 76-year-old man presented clinically with coughing and shortness of breath and was diagnosed radiologically to have massive pleural effusion as a combined feature of yellow nail syndrome. A lung biopsy was taken and revealed histologically: chronic non-specific inflammation in the pleuropulmonary border, intrapleural edema with eightfold pleural thickening in comparison to normal, angiogenesis in both the nutritive and functional intrapleural blood vessels, no abnormalities of lymphatic vessels with normal topographical distribution as detected by immunohistochemistry for antibody D2-40, granulomatous chronic foreign body reaction as a consequence of pleural effusion therapy by talcum pleurodesis.The histopathological findings of chronic non-specific pleuritis with angiogenesis and increased permeability of blood vessels led to massive intrapleural edema with pleural effusion. Abnormalities of lymphatic vessels could not be confirmed. Considering the features of this disease, they are probably secondary to chronic r infectious or immunological inflammation or paraneoplastic complications with angiogenesis (in about 19%).
A Convenient Method of Decomposing the Gini Index by Population Subgroups
Ogwang Tomson
2014-03-01
Full Text Available We propose a convenient method of estimating the within-group, between-group, and interaction components of the overall traditional Gini index from the estimated parameters of underlying “trick regression models” involving known forms of heteroscedasticity related to income. Two illustrative examples involving both real and artificial data are provided. The issue of appropriate standard error of the subgroup decomposition is also discussed.
February 2014 Phoenix critical care journal club: subgroup analysis
Robbins RA
2014-02-01
Full Text Available No abstract available. Article truncated at 150 words. Sun X, Ioannidis JP, Agoritsas T, Alba AC, Guyatt G. How to use a subgroup analysis: users' guide to the medical literature. JAMA. 2014;311(4:405-11. One of Dr. Raschke's pet peeves is unplanned subgroup analysis. In the September 2013 Banner Good Samaritan / Phoenix VA Critical Care Journal Club (1 he commented on an article by Hung et al. (2 that used a post hoc subgroup analysis. He felt strongly enough to write to the editor about why post hoc subgroup analysis should not be acceptable as a basis for scientific conclusions and his letter was published this month (3. Therefore, we have been on the lookout for a review article to discuss subgroup analysis and came across this timely publication in JAMA. The authors cite a number of examples and provide 5 criteria to use when assessing the validity of subgroup analyses: 1. Can chance explain the apparent subgroup effect ...
Kamoun, Aurélie; Idbaih, Ahmed; Dehais, Caroline; Elarouci, Nabila; Carpentier, Catherine; Letouzé, Eric; Colin, Carole; Mokhtari, Karima; Jouvet, Anne; Uro-Coste, Emmanuelle; Martin-Duverneuil, Nadine; Sanson, Marc; Delattre, Jean-Yves; Figarella-Branger, Dominique; de Reyniès, Aurélien
2016-01-01
POLA Network; International audience; Oligodendroglial tumours (OT) are a heterogeneous group of gliomas. Three molecular subgroups are currently distinguished on the basis of the IDH mutation and 1p/19q co-deletion. Here we present an integrated analysis of the transcriptome, genome and methylome of 156 OT. Not only does our multi-omics classification match the current classification but also reveals three subgroups within 1p/19q co-deleted tumours, associated with specific expression patter...
S. Mehta
2016-01-01
Full Text Available Objective. The current study attempted to identify and characterize distinct CP subgroups based on their level of dispositional personality traits. The secondary objective was to compare the difference among the subgroups in mood, coping, and disability. Methods. Individuals with chronic pain were assessed for demographic, psychosocial, and personality measures. A two-step cluster analysis was conducted in order to identify distinct subgroups of patients based on their level of personality traits. Differences in clinical outcomes were compared using the multivariate analysis of variance based on cluster membership. Results. In 229 participants, three clusters were formed. No significant difference was seen among the clusters on patient demographic factors including age, sex, relationship status, duration of pain, and pain intensity. Those with high levels of dispositional personality traits had greater levels of mood impairment compared to the other two groups (p<0.05. Significant difference in disability was seen between the subgroups. Conclusions. The study identified a high risk group of CP individuals whose level of personality traits significantly correlated with impaired mood and coping. Use of pharmacological treatment alone may not be successful in improving clinical outcomes among these individuals. Instead, a more comprehensive treatment involving psychological treatments may be important in managing the personality traits that interfere with recovery.
Identifying flavor preference subgroups. Genetic basis and related eating behavior traits.
Törnwall, Outi; Silventoinen, Karri; Hiekkalinna, Tero; Perola, Markus; Tuorila, Hely; Kaprio, Jaakko
2014-04-01
Subgroups based on flavor preferences were identified and their genetic and behavior related characteristics investigated using extensive data from 331 Finnish twins (21-25years, 146 men) including 47 monozygotic (MZ) and 93 dizygotic (DZ) pairs, and 51 twin individuals. The subgroup identification (hierarchical and K-means clustering) was based on liking responses to food names representing sour, umami, and spicy flavor qualities. Furthermore, sensory tests were conducted, a questionnaire on food likes completed, and various eating behavior related traits measured with validated scales. Sensory data included intensity ratings of PROP (6-n-propylthiouracil-impregnated filter paper), hedonic and intensity responses to sourness (orange juice with and without added citric acid, 0.42%), pungency (strawberry jelly with and without added capsaicin 0.00013%) and umami ('mouthfeel flavor' taste solution). Ratings of liking of 41 general food names were categorized into salty-and-fatty, sweet-and-fatty, fruits and vegetables and fish foods. Subgroup differences (complex samples procedure) and the genetics underlying the subgroups (structural equation modeling) were investigated. Of the resulting two groups (basic, n=140, adventurous n=152; non-grouped n=39), the adventurous expressed higher liking for sour and spicy foods, and had more tolerance for capsaicin burn in the sensory-hedonic test. The adventurous were also less food neophobic (25.9±9.1 vs. 32.5±10.6, respectively) and expressed higher liking for fruits and vegetables compared to the basic group. Genetic effects were shown to underlie the subgroups (heritability 72%, CI: 36-92%). Linkage analysis for 27 candidate gene regions revealed suggestively that being adventurous is linked to TAS1R1 and PKD1L3 genes. These results indicate that food neophobia and genetic differences may form a barrier through which individual flavor preferences are generated.
Leading Causes of Death among Asian American Subgroups (2003-2011).
Hastings, Katherine G; Jose, Powell O; Kapphahn, Kristopher I; Frank, Ariel T H; Goldstein, Benjamin A; Thompson, Caroline A; Eggleston, Karen; Cullen, Mark R; Palaniappan, Latha P
2015-01-01
Our current understanding of Asian American mortality patterns has been distorted by the historical aggregation of diverse Asian subgroups on death certificates, masking important differences in the leading causes of death across subgroups. In this analysis, we aim to fill an important knowledge gap in Asian American health by reporting leading causes of mortality by disaggregated Asian American subgroups. We examined national mortality records for the six largest Asian subgroups (Asian Indian, Chinese, Filipino, Japanese, Korean, Vietnamese) and non-Hispanic Whites (NHWs) from 2003-2011, and ranked the leading causes of death. We calculated all-cause and cause-specific age-adjusted rates, temporal trends with annual percent changes, and rate ratios by race/ethnicity and sex. Rankings revealed that as an aggregated group, cancer was the leading cause of death for Asian Americans. When disaggregated, there was notable heterogeneity. Among women, cancer was the leading cause of death for every group except Asian Indians. In men, cancer was the leading cause of death among Chinese, Korean, and Vietnamese men, while heart disease was the leading cause of death among Asian Indians, Filipino and Japanese men. The proportion of death due to heart disease for Asian Indian males was nearly double that of cancer (31% vs. 18%). Temporal trends showed increased mortality of cancer and diabetes in Asian Indians and Vietnamese; increased stroke mortality in Asian Indians; increased suicide mortality in Koreans; and increased mortality from Alzheimer's disease for all racial/ethnic groups from 2003-2011. All-cause rate ratios revealed that overall mortality is lower in Asian Americans compared to NHWs. Our findings show heterogeneity in the leading causes of death among Asian American subgroups. Additional research should focus on culturally competent and cost-effective approaches to prevent and treat specific diseases among these growing diverse populations.
Application of Subgroup Method in TPFAP Library
LIU; Ping
2012-01-01
<正>TPFAP is a transmission probability fuel assembly code package for burn-up calculations on BWR and PWR. The transport calculation is started with a number of energy group calculations in the TPFAP nuclear data library by using of collision probability method. The method of calculating resonance shielding effects in TPFAP library is equivalence theory which uses the intermediate resonance approximations to derive an effective background scatter cross section sigma-p. The equivalence theory is limited by the available algorithms for determining the so-called ’equivalent’ sigma-p value in complex geometries.
Jun Wang; Guoqing Chen; Tuo Zhu; Shumei Gao; Bailin Wei; Linna Bi
2009-01-01
@@ The fluorescence spectra of synthetic food dyes of sunset yellow and tartrazine are analyzed.The fluorescence peak wavelengths of sunset yellow and tartrazine are 576 and 569 nm, respectively, while the fluorescence spectra widths are 480-750 and 500-750 nm induced by ultraviolet light between 310-400 nm.The fluorescence spectra of sunset yellow overlap heavily with those of tartrazine, so it is diffic ult to distinguish them.Based on the principle of radial basis function neural network, a neural network is obtained from the training of the 14 groups of experimental data.The results show that the species of sunset yellow and tartrazine could be recognized accurately.This method has potential applications in other synthetic food dyes detection and food safety inspection.
On -supersolvability of finite groups
Izabela Agata Malinowska
2015-05-01
A number of authors have studied the structure of a group under the assumption that some subgroups of are well located in . We will obtain some new criteria of -supersolvability and -nilpotency of groups.
Jingqun Ao
2015-11-01
Full Text Available High-density genetic maps are essential for genome assembly, comparative genomic analysis and fine mapping of complex traits. In this study, 31,191 single nucleotide polymorphisms (SNPs evenly distributed across the large yellow croaker (Larimichthys crocea genome were identified using restriction-site associated DNA sequencing (RAD-seq. Among them, 10,150 high-confidence SNPs were assigned to 24 consensus linkage groups (LGs. The total length of the genetic linkage map was 5451.3 cM with an average distance of 0.54 cM between loci. This represents the densest genetic map currently reported for large yellow croaker. Using 2889 SNPs to target specific scaffolds, we assigned 533 scaffolds, comprising 421.44 Mb (62.04% of the large yellow croaker assembled sequence, to the 24 linkage groups. The mapped assembly scaffolds in large yellow croaker were used for genome synteny analyses against the stickleback (Gasterosteus aculeatus and medaka (Oryzias latipes. Greater synteny was observed between large yellow croaker and stickleback. This supports the hypothesis that large yellow croaker is more closely related to stickleback than to medaka. Moreover, 1274 immunity-related genes and 195 hypoxia-related genes were mapped to the 24 chromosomes of large yellow croaker. The integration of the high-resolution genetic map and the assembled sequence provides a valuable resource for fine mapping and positional cloning of quantitative trait loci associated with economically important traits in large yellow croaker.
Clara Maass, yellow fever and human experimentation.
Chaves-Carballo, Enrique
2013-05-01
Clara Louise Maass, a 25-year-old American nurse, died of yellow fever on August 24, 1901, following experimental inoculation by infected mosquitoes in Havana, Cuba. The human yellow fever experiments were initially conducted by MAJ Walter Reed, who first used written informed consent and proved the validity of Finlay's mosquito-vector hypothesis. Despite informed consent form and an incentive of $100 in U.S. gold, human subjects were exposed to a deadly virus. The deaths of Clara Maass and two Spanish immigrants resulted in a public outcry and the immediate cessation of yellow fever human experiments in Cuba.
Hippocrates, cardiology, Confucius and the Yellow Emperor.
Cheng, T O
2001-12-01
Although Hippocrates (460-c.375 BC) has been traditionally recognized as the Father of Medicine, the fact that he was seminal in the development of cardiology is much less well known. Evidence is presented to support the notion that Hippocrates could also be considered the Father of Cardiology. Hippocrates also had many of the teachings and practices in common with Confucius (c.551-c.479 BC) and the Yellow Emperor of China (2695-2589 BC). Whereas Confucius was not a physician, the Yellow Emperor was an ancient Chinese physician whose Huang Di Neijing, the Yellow Emperor's Canon of Internal Medicine, is the oldest known treatise of medicine in existence.
Roberts, Darren M; Southcott, Emma; Potter, Julia M; Roberts, Michael S; Eddleston, Michael; Buckley, Nick A
2006-12-01
Intentional self-poisonings with seeds from the yellow oleander tree (Thevetia peruviana) are widely reported. Activated charcoal has been suggested to benefit patients with yellow oleander poisoning by reducing absorption and/or facilitating elimination. Two recent randomized controlled trials (RCTs) assessing the efficacy of activated charcoal yielded conflicting outcomes in terms of mortality. The effect of activated charcoal on the pharmacokinetics of Thevetia cardenolides has not been assessed. This information may be useful for determining whether further studies are necessary. Serial blood samples were obtained from patients enrolled in an RCT assessing the relative efficacy of single-dose and multiple-dose activated charcoal (SDAC and MDAC, respectively) compared with no activated charcoal (NoAC). The concentration of Thevetia cardenolides was estimated with a digoxin immunoassay. The effect of activated charcoal on cardenolide pharmacokinetics was compared between treatment groups by determining the area under the curve for each patient in the 24 hours following admission, the 24-hour mean residence time, and regression lines obtained from serial concentration points, adjusted for exposure. Erratic and prolonged absorption patterns were noted in each patient group. The apparent terminal half-life was highly variable, with a median time of 42.9 hours. There was a reduction in 24-hour mean residence time and in the apparent terminal half-life estimated from linear regression in patients administered activated charcoal, versus the control group (NoAC). This effect was approximately equal in patients administered MDAC or SDAC. Activated charcoal appears to favorably influence the pharmacokinetic profile of Thevetia cardenolides in patients with acute self-poisoning and may have clinical benefits. Given the conflicting clinical outcomes noted in previous RCTs, these mechanistic data support the need for further studies to determine whether a particular subgroup
Learning Clinical Workflows to Identify Subgroups of Heart Failure Patients
Yan, Chao; Chen, You; Li, Bo; Liebovitz, David; Malin, Bradley
2016-01-01
Heart Failure (HF) is one of the most common indications for readmission to the hospital among elderly patients. This is due to the progressive nature of the disease, as well as its association with complex comorbidities (e.g., anemia, chronic kidney disease, chronic obstructive pulmonary disease, hyper- and hypothyroidism), which contribute to increased morbidity and mortality, as well as a reduced quality of life. Healthcare organizations (HCOs) have established diverse treatment plans for HF patients, but such routines are not always formalized and may, in fact, arise organically as a patient’s management evolves over time. This investigation was motivated by the hypothesis that patients associated with a certain subgroup of HF should follow a similar workflow that, once made explicit, could be leveraged by an HCO to more effectively allocate resources and manage HF patients. Thus, in this paper, we introduce a method to identify subgroups of HF through a similarity analysis of event sequences documented in the clinical setting. Specifically, we 1) structure event sequences for HF patients based on the patterns of electronic medical record (EMR) system utilization, 2) identify subgroups of HF patients by applying a k-means clustering algorithm on utilization patterns, 3) learn clinical workflows for each subgroup, and 4) label each subgroup with diagnosis and procedure codes that are distinguishing in the set of all subgroups. To demonstrate its potential, we applied our method to EMR event logs for 785 HF inpatient stays over a 4 month period at a large academic medical center. Our method identified 8 subgroups of HF, each of which was found to associate with a canonical workflow inferred through an inductive mining algorithm. Each subgroup was further confirmed to be affiliated with specific comorbidities, such as hyperthyroidism and hypothyroidism. PMID:28269922
Subgrouping Chronic Fatigue Syndrome Patients by Genetic and Immune Profiling
2014-10-01
AWARD NUMBER: W81XWH-12-1-0388 TITLE: Subgrouping Chronic Fatigue Syndrome Patients by Genetic and Immune Profiling ...2014 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Subgrouping Chronic Fatigue Syndrome Patients By Genetic And Immune Profiling 5b. GRANT...studying the results. We have finished the DNA isolation and anticipate the HLA testing to be completed this upcoming year. We want to interrogate the
Disproportionate sampling for population subgroups in telephone surveys.
Kalsbeek, William D; Boyle, Walter R; Agans, Robert P; White, John E
2007-04-15
Population studies often seek to examine phenomena in important population subgroups or to compare results among these and other subgroups. When subgroups of interest comprise a relatively small percentage of the population and acceptable subgroup member lists are not available to serve as sampling frames, it may be prohibitively expensive even by telephone to screen through a sample of the entire population. This paper considers some statistical effects of estimation from a class of two-stratum telephone sample designs where part of the frame with a higher subgroup concentration is disproportionately sampled compared to the rest of the frame. Using proportionate sampling as a reference, the relative impact of this disproportionate design is determined for nominal and effective sample sizes, where the latter are tied to the effect of variation in sample weights that occurs in disproportionately allocated samples. Findings are illustrated using two recent telephone surveys. Whereas nominal subgroup sample sizes may be improved by disproportionate sampling, we conclude that both the survey designer and analyst should use this type of design cautiously in telephone surveys.
A Bayesian subgroup analysis using collections of ANOVA models.
Liu, Jinzhong; Sivaganesan, Siva; Laud, Purushottam W; Müller, Peter
2017-03-20
We develop a Bayesian approach to subgroup analysis using ANOVA models with multiple covariates, extending an earlier work. We assume a two-arm clinical trial with normally distributed response variable. We also assume that the covariates for subgroup finding are categorical and are a priori specified, and parsimonious easy-to-interpret subgroups are preferable. We represent the subgroups of interest by a collection of models and use a model selection approach to finding subgroups with heterogeneous effects. We develop suitable priors for the model space and use an objective Bayesian approach that yields multiplicity adjusted posterior probabilities for the models. We use a structured algorithm based on the posterior probabilities of the models to determine which subgroup effects to report. Frequentist operating characteristics of the approach are evaluated using simulation. While our approach is applicable in more general cases, we mainly focus on the 2 × 2 case of two covariates each at two levels for ease of presentation. The approach is illustrated using a real data example.
Dispositional Affect in Unique Subgroups of Patients with Rheumatoid Arthritis
Danielle B. Rice
2016-01-01
Full Text Available Background. Patients with rheumatoid arthritis may experience increased negative outcomes if they exhibit specific patterns of dispositional affect. Objective. To identify subgroups of patients with rheumatoid arthritis based on dispositional affect. The secondary objective was to compare mood, pain catastrophizing, fear of pain, disability, and quality of life between subgroups. Methods. Outpatients from a rheumatology clinic were categorized into subgroups by a cluster analysis based on dispositional affect. Differences in outcomes were compared between clusters through multivariate analysis of covariance. Results. 227 patients were divided into two subgroups. Cluster 1 (n=85 included patients reporting significantly higher scores on all dispositional variables (experiential avoidance, anxiety sensitivity, worry, fear of pain, and perfectionism; all p<0.001 compared to patients in Cluster 2 (n=142. Patients in Cluster 1 also reported significantly greater mood impairment, pain anxiety sensitivity, and pain catastrophizing (all p<0.001. Clusters did not differ on quality of life or disability. Conclusions. The present study identifies a subgroup of rheumatoid arthritis patients who score significantly higher on dispositional affect and report increased mood impairment, pain anxiety sensitivity, and pain catastrophizing. Considering dispositional affect within subgroups of patients with RA may help health professionals tailor interventions for the specific stressors that these patients experience.
Johnston Atoll - Eradication of Yellow Crazy Ants
US Fish and Wildlife Service, Department of the Interior — While on a research and monitoring cruise that visited Johnston Atoll in late January 2010, USFWS employees found an infestation of Anoplolepis gracilipes, or yellow...
Lost trust: a yellow fever patient response.
Runge, John S
2013-12-13
In the 19th century, yellow fever thrived in the tropical, urban trade centers along the American Gulf Coast. Industrializing and populated, New Orleans and Memphis made excellent habitats for the yellow fever-carrying Aedes aegypti mosquitoes and the virulence they imparted on their victims. Known for its jaundice and black, blood-filled vomit, the malady terrorized the region for decades, sometimes claiming tens of thousands of lives during the near annual summertime outbreaks. In response to the failing medical community, a small, pronounced population of sick and healthy laypeople openly criticized the efforts to rid the Gulf region of yellow jack. Utilizing newspapers and cartoons to vocalize their opinions, these critics doubted and mocked the medical community, contributing to the regional and seasonal dilemma yellow fever posed for the American South. These sentient expressions prove to be an early example of patient distrust toward caregivers, a current problem in clinical heath care.
Yellow River Delta Faces a Historic Opportunity
Li Zhen
2010-01-01
@@ China's State Council has endorsed the Development Plan of an Efficient Eco-Economic Zone at Yellow River Delta. The plan is meant to create a more ecologically sustainable economic zone along the river delta.
Yellow River Delta Faces a Historic Opportunity
Li Zhen
2011-01-01
@@ China's State Council has endorsed the Development Plan of an Efficient Eco-Economic Zone at Yellow River Delta.The plan is meant to create a more ecologically sustainable economic zone along the river delta.
1999 Yellow River Aerial Photos, Central Wisconsin
U.S. Geological Survey, Department of the Interior — The 25-mile stretch of the Yellow River adjacent to the Necedah National Wildlife Refuge in Central Wisconsin provides valuable habitat to numerous species of...
Thermomechanical behavior of comercial yellow gold alloy
Miloš G. Djordjević
2016-03-01
Full Text Available With the development of science and technology, in the late 19th century, began the research and application of new alloys for making jewelry. By adding different amounts of Cu and Ag alloy of Au, as well as adding some new elements (Zn, alloys were obtained with different color spectrum (from red to yellow and different technological and metallurgical characteristics. This paper aims to show thermomechanical behavior of commercial yellow Au alloys for making jewelry.
Redox alters yellow dragonflies into red.
Futahashi, Ryo; Kurita, Ryoji; Mano, Hiroaki; Fukatsu, Takema
2012-07-31
Body color change associated with sexual maturation--so-called nuptial coloration--is commonly found in diverse vertebrates and invertebrates, and plays important roles for their reproductive success. In some dragonflies, whereas females and young males are yellowish in color, aged males turn vivid red upon sexual maturation. The male-specific coloration plays pivotal roles in, for example, mating and territoriality, but molecular basis of the sex-related transition in body coloration of the dragonflies has been poorly understood. Here we demonstrate that yellow/red color changes in the dragonflies are regulated by redox states of epidermal ommochrome pigments. Ratios of reduced-form pigments to oxidized-form pigments were significantly higher in red mature males than yellow females and immature males. The ommochrome pigments extracted from the dragonflies changed color according to redox conditions in vitro: from red to yellow in the presence of oxidant and from yellow to red in the presence of reductant. By injecting the reductant solution into live insects, the yellow-to-red color change was experimentally reproduced in vivo in immature males and mature females. Discontinuous yellow/red mosaicism was observed in body coloration of gynandromorphic dragonflies, suggesting a cell-autonomous regulation over the redox states of the ommochrome pigments. Our finding extends the mechanical repertoire of pigment-based body color change in animals, and highlights an impressively simple molecular mechanism that regulates an ecologically important color trait.
Narcolepsy Following Yellow Fever Vaccination: A Case Report.
Rosch, Richard E; Farquhar, Michael; Gringras, Paul; Pal, Deb K
2016-01-01
Narcolepsy with cataplexy is a rare, but important differential diagnosis for daytime sleepiness and atonic paroxysms in an adolescent. A recent increase in incidence in the pediatric age group probably linked to the use of the Pandemrix influenza vaccine in 2009, has increased awareness that different environmental factors can "trigger" narcolepsy with cataplexy in a genetically susceptible population. Here, we describe the case of a 13-year-old boy with narcolepsy following yellow fever vaccination. He carries the HLA DQB1*0602 haplotype strongly associated with narcolepsy and cataplexy. Polysomnography showed rapid sleep onset with rapid eye movement (REM) latency of 47 min, significant sleep fragmentation and a mean sleep latency of 1.6 min with sleep onset REM in four out of four nap periods. Together with the clinical history, these findings are diagnostic of narcolepsy type 1. The envelope protein E of the yellow fever vaccine strain 17D has significant amino acid sequence overlap with both hypocretin and the hypocretin receptor 2 receptors in protein regions that are predicted to act as epitopes for antibody production. These findings raise the question whether the yellow fever vaccine strain may, through a potential molecular mimicry mechanism, be another infectious trigger for this neuro-immunological disorder.
Narcolepsy following yellow fever vaccination: A case report
Richard Ewald Rosch
2016-08-01
Full Text Available Narcolepsy with cataplexy is a rare, but important differential diagnosis for daytime sleepiness and atonic paroxysms in an adolescent. A recent increase in incidence in the paediatric age-group probably linked to the use of the Pandremix influenza vaccine in 2009, has increased awareness that different environmental factors can ‘trigger’ narcolepsy with cataplexy in a genetically susceptible population.Here we describe the case of a 13 year-old boy with narcolepsy following yellow-fever vaccination. He carries the HLA DQB1*0602 haplotype strongly associated with narcolepsy and cataplexy. Polysomnography showed rapid sleep onset with rapid eye movement (REM latency of 47 minutes, significant sleep fragmentation and a mean sleep latency of 1.6 minutes with sleep onset REM in 4 out of 4 nap periods. Together with the clinical history, these findings are diagnostic of narcolepsy type 1. The envelope protein E of the yellow fever vaccine strain 17D has significant amino acid sequence overlap with both hypocretin and the hypocretin receptor 2 receptors in protein regions that are predicted to act as epitopes for antibody production. These findings raise the question whether the yellow fever vaccine strain may, through a potential molecular mimicry mechanism, be another infectious trigger for this neuro-immunological disorder.
Development of Rural Banks in Yellow River Delta
2010-01-01
The status quo of new-type rural financial institutions in the Yellow River delta is summarized.It is pointed out that these financial institutions have improved the development of economy concerning agriculture,rural areas and peasants,but due to the shortage of capital,deficit and many other reasons,the outlets is fewer,which can not serve the agriculture,rural areas and peasants well.The necessity of developing rural banks in the Yellow River delta is introduced:firstly,rural banks can serve the agriculture,rural areas and peasants well with flexible system and management methods.Secondly,rural banks can serve and support the vulnerable groups of the three rural issues concerning agriculture,countryside and famers well.Thirdly,rural banks provide strong support for the all around development of rural business concerning the agriculture,rural areas and peasants.Fourthly,rural banks have significant advantages in serving the agriculture,rural areas and peasants.The probability of developing rural banks in the Yellow River delta is analyzed from the three advantages of policy,environment and economy.The challenges faced by the development of rural banks are studied as follows:firstly,the short-term profits are hard to take effect.Secondly,the capital quantity of rural banks is large.Thirdly,the pressure of competition and operation is great.Thus the countermeasures of developing rural banks in the Yellow River delta are put forward:for instance,clarifying the service object in a certain area;using the minority to bring along the majority;reducing the risk of asymmetric information by information technology.
Genetically meaningful phenotypic subgroups in autism spectrum disorders.
Veatch, O J; Veenstra-Vanderweele, J; Potter, M; Pericak-Vance, M A; Haines, J L
2014-03-01
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with strong evidence for genetic susceptibility. However, the effect sizes for implicated chromosomal loci are small, hard to replicate and current evidence does not explain the majority of the estimated heritability. Phenotypic heterogeneity could be one phenomenon complicating identification of genetic factors. We used data from the Autism Diagnostic Interview-Revised, Autism Diagnostic Observation Schedule, Vineland Adaptive Behavior Scales, head circumferences, and ages at exams as classifying variables to identify more clinically similar subgroups of individuals with ASD. We identified two distinct subgroups of cases within the Autism Genetic Resource Exchange dataset, primarily defined by the overall severity of evaluated traits. In addition, there was significant familial clustering within subgroups (odds ratio, OR ≈ 1.38-1.42, P Autism Genome Project, we similarly identified two distinct subgroups of cases and confirmed this severity-based dichotomy. We also observed evidence for genetic contributions to subgroups identified in the replication dataset. Our results provide more effective methods of phenotype definition that should increase power to detect genetic factors influencing risk for ASD.
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Smalley, Keiran S M; Contractor, Rooha; Nguyen, Thiennga K; Xiao, Min; Edwards, Robin; Muthusamy, Viswanathan; King, Alastair J; Flaherty, Keith T; Bosenberg, Marcus; Herlyn, Meenhard; Nathanson, Katherine L
2008-07-15
Although many melanomas harbor either activating mutations in BRAF or NRAS, there remains a substantial, yet little known, group of tumors without either mutation. Here, we used a genomic strategy to define a novel group of melanoma cell lines with co-overexpression of cyclin-dependent kinase 4 (CDK4) and KIT. Although this subgroup lacked any known KIT mutations, they had high phospho-KIT receptor expression, indicating receptor activity. Quantitative PCR confirmed the existence of a similar KIT/CDK4 subgroup in human melanoma samples. Pharmacologic studies showed the KIT/CDK4-overexpressing subgroup to be resistant to BRAF inhibitors but sensitive to imatinib in both in vitro and in vivo melanoma models. Mechanistically, imatinib treatment led to increased apoptosis and G(1) phase cell cycle arrest associated with the inhibition of phospho-ERK and increased expression of p27(KIP). Other melanoma cell lines, which retained some KIT expression but lacked phospho-KIT, were not sensitive to imatinib, suggesting that KIT expression alone is not predictive of response. We suggest that co-overexpression of KIT/CDK4 is a potential mechanism of oncogenic transformation in some BRAF/NRAS wild-type melanomas. This group of melanomas may be a subpopulation for which imatinib or other KIT inhibitors may constitute optimal therapy.
Rebeca Zanini
2015-12-01
Full Text Available ABSTRACT In several arthropod groups, male genitalia is the most important feature for species identification, especially in cryptic species. Cryptic species are very common in the Drosophila genus, and the Neotropical Drosophila willistoni species group is a good example. This group currently includes 24 species divided into three subgroups: alagitans, bocainensis and willistoni. There are six sibling species in the willistoni subgroup – D. willistoni, D. insularis, D. tropicalis, D. equinoxialis, D. pavlovskiana and D. paulistorum, which is a species complex composed of six semispecies – Amazonian, Andean-Brazilian, Centroamerican, Interior, Orinocan and Transitional. The objective of this study was to characterize male genitalia of the willistoni subgroup, including the D. paulistorum species complex, using scanning electron microscopy and light microscopy. We also tried to contribute to the identification of these cryptic species and to add some comments about evolutionary history, based on male genitalia characters. Despite being cryptic species, some differences were found among the siblings, including the Drosophila paulistorum semispecies.
Walzer, Amy S; Czopp, Alexander M
2011-01-01
The stereotype content model (SCM) posits that warmth and competence are the key components underlying judgments about social groups. Because competence can encompass different components (e.g., intelligence, talent) different group members may be perceived to be competent for different reasons. Therefore, we believe it may be important to specify the type of competence being assessed when examining perceptions of groups that are positively stereotyped (i.e., Black athletes and musical Blacks). Consistent with the SCM, these subgroups were perceived as high in competence-talent but not in competence-intelligence and low in warmth. Both the intelligence and talent frame of competence fit in the SCM's social structural hypothesis.
Vaegter, Henrik B.; Graven-Nielsen, Thomas
2016-01-01
between subgroups. Cuff algometry was performed on lower legs in 400 chronic pain patients to assess pressure pain threshold (cPPT), pressure pain tolerance (cPTT), temporal summation of pain (TSP: increase in pain scores to ten repeated stimulations), and conditioned pain modulation (CPM: increase in c......PPT during cuff pain conditioning on the contralateral leg). Heat detection (HDT) and heat pain thresholds (HPT) at clinical painful and non-painful body areas were assessed. Based on TSP and CPM four distinct groups were formed: Group 1 (n=85) had impaired CPM and facilitated TSP. Group 2 (n=148) had...... impaired CPM and normal TSP. Group 3 (n=45) had normal CPM and facilitated TSP. Group 4 (n=122) had normal CPM and normal TSP. Group 1 showed more pain regions compared with the other three groups (PCPM and facilitated TSP plays an important role in widespread pain. Group 1...
Vaegter, Henrik Bjarke; Graven-Nielsen, Thomas
2016-01-01
between subgroups. Cuff algometry was performed on lower legs in 400 chronic pain patients to assess pressure pain threshold (cPPT), pressure pain tolerance (cPTT), temporal summation of pain (TSP: increase in pain scores to ten repeated stimulations), and conditioned pain modulation (CPM: increase in c......PPT during cuff pain conditioning on the contralateral leg). Heat detection (HDT) and heat pain thresholds (HPT) at clinical painful and non-painful body areas were assessed. Based on TSP and CPM four distinct groups were formed: Group 1 (n=85) had impaired CPM and facilitated TSP. Group 2 (n=148) had...... impaired CPM and normal TSP. Group 3 (n=45) had normal CPM and facilitated TSP. Group 4 (n=122) had normal CPM and normal TSP. Group 1 showed more pain regions compared with the other three groups (PCPM and facilitated TSP plays an important role in widespread pain. Group 1...
Casper H. van Heck
2017-05-01
Full Text Available Little is known regarding inter-individual differences in attentional biases for pain-related information; more knowledge is crucial, since these biases have been associated with differences in pain processing as well as in predicting the risk of postoperative pain. The present study investigated EEG correlates of attentional bias patterns for pain-related information, with specific focus on avoidance- and vigilance-like behavior. Forty-one participants performed a dot-probe task, where neutral and pain-related words were used to create neutral, congruent, incongruent, and double (two pain-related words trials. EEG was recorded, which was used to generate ERP's of the word-processing phase and the post-dot phase. Participants were placed in two subgroups based on the direction of their attentional bias (either positive; toward the pain-related words, or negative; away from pain-related words. Using t-profiles, four latency windows were identified on which the two subgroups differed significantly. These latency windows yield areas which correspond with the P1-N1 domain and the P3b for the word-processing phase, while the post-dot phase latency windows cover the areas of the P200 and the P3b. The two subgroups show differences on congruent, incongruent, and the double trials, but interestingly also on the neutral trials. Most notably, the area in the word-phase associated with the P3b is diminished in the subgroup showing a negative bias. The deflections associated with both early and late attentional components, including the P3B, as well as a positive deflection in the timeframe of proposed response evaluation processes differ significantly between subgroups. In this study we demonstrated that different attentional biases exist in the healthy population, by showing differences in ERP's. We also show differences in processing neutral trials, which suggests there are fundamental differences between these groups in processing words in general.
Gil-Salas, Francisco M; Peters, Jeff; Boonham, Neil; Cuadrado, Isabel M; Janssen, Dirk
2011-11-01
Zucchini squash is host to Cucurbit yellow stunting disorder virus (CYSDV), a member of the genus Crinivirus, and Cucumber vein yellowing virus (CVYV), a member of the genus Ipomovirus, both transmitted by the whitefly Bemisia tabaci. Field observations suggest the appearance of new symptoms observed on leaves of zucchini squash crops when both viruses were present. When infected during controlled experiments with CYSDV only, zucchini plants showed no obvious symptoms and the virus titer decreased between 15 and 45 days postinoculation (dpi), after which it was no longer detected. CVYV caused inconspicuous symptoms restricted to vein clearing on some of the apical leaves and the virus accumulated progressively between 15 and 60 dpi. Similar accumulations of virus followed single inoculations with the potyvirus Zucchini yellow mosaic virus (ZYMV) and plants showed severe stunting, leaf deformation, and mosaic yellowing. However, in mixed infections with CYSDV and CVYV, intermediate leaves showed chlorotic mottling which evolved later to rolling, brittleness, and complete yellowing of the leaf lamina, with exception of the veins. No consistent alteration of CVYV accumulation was detected but the amounts of CYSDV increased ≈100-fold and remained detectable at 60 dpi. Such synergistic effects on the titer of the crinivirus and symptom expression were not observed when co-infected with ZYMV.
Melnikova, Larisa; Kostuchenko, Margarita; Silicheva, Margarita; Georgiev, Pavel
2008-04-01
There is ample evidence that the enhancers of a promoterless yellow locus in one homologous chromosome can activate the yellow promoter in the other chromosome where the enhancers are inactive or deleted, which is indicative of a high specificity of the enhancer-promoter interaction in yellow. In this paper, we have found that the yellow sequence from -100 to -69 is essential for stimulation of the heterologous eve (TATA-containing) and white (TATA-less) promoters by the yellow enhancers from a distance. However, the presence of this sequence is not required when the yellow enhancers are directly fused to the heterologous promoters or are activated by the yeast GAL4 activator. Unexpectedly, the same promoter proximal region defines previously described promoter-specific, long-distance repression of the yellow promoter by the gypsy insulator on the mod(mdg4) ( u1 ) background. These finding suggest that proteins bound to the -100 to -69 sequence are essential for communication between the yellow promoter and upstream regulatory elements.
Palomo-Álvarez, Catalina; Puell, María C
2013-03-01
Possible beneficial effects of yellow-tinted spectacle lenses on binocular vision, accommodation, oculomotor scanning, reading speed and visual symptoms were assessed in children with reading difficulties. A longitudinal prospective study was performed in 82 non-dyslexic children with reading difficulties in grades 3-6 (aged 9-11 years) from 11 elementary schools in Madrid (Spain). The children were randomly assigned to two groups: a treatment (n = 46) and a without-treatment group (n = 36). Children in the treatment group wore yellow spectacle lenses with best correction if necessary over 3 months (in school and at home). The tests were first undertaken without the yellow filter. With best spectacle correction in each subject, measurements were made of: distance and near horizontal heterophoria, distance and near horizontal fusional vergence ranges, the accommodative convergence/accommodation (AC/A) ratio, near point of convergence (NPC), stereoacuity, negative relative accommodation (NRA) and positive relative accommodation (PRA), monocular accommodative amplitude (MAA), binocular accommodative facility (BAF), oculomotor scanning, and reading speed (words per minute). The Convergence Insufficiency Symptom Survey (CISS) questionnaire was completed by all children. After the 3-month period, measurements were repeated with the yellow lenses (treatment group) or without the yellow lenses (without-treatment group) but with refractive correction if needed. Over the 3 months, the two groups showed similar mean changes in the variables used to assess binocular vision, accommodation, oculomotor scanning, and reading speed. However, mean relative changes in convergence insufficiency symptoms differed significantly between the groups (p = 0.01). No effects of wearing yellow spectacles emerged on binocular vision, accommodation, oculomotor scanning, and reading speed in children with reading difficulties. The yellow filter had no effect even in children with low MAA and BAF
李朝
2012-01-01
本文以民族民间叙事作为多民族文化构成的重要表现方式，认为青藏高原的河湟地区那些讲述族源叙事口头文本在多民族聚居的区域社会内部和族际之间，实际上历来都是一种跨族际交往的对话模式，在叙事中来历不同的族群通过话语重置、取向偏离、重心移位、情境再造等复述性传播，使得跨族际交往成为可能，认同关系随之发生变化而趋于一体。同时，试图通过一个实在的细节层面论述，指出为学界津津乐道的西方“民族国家”理论在中国的不适。%This paper holds that the unwritten versions of folk narratives, the most important form of expression of multi-ethnic cultures,in relation to the origin of the ethnic groups in the Huangshui and the Yellow River Regions are actually an intra-regional and inter-ethnic communication dialogue between the different ethnic groups settled on the multi-ethnic regions of Qinghai-Tibet Plateau. As is evident in these narratives, inter-ethnic communication has been made possible with the dissemination of varied ver- sions of resembling folklores adapted by different ethnic groups with such narrative skills as discourse rear- rangement,preferred orientation, content transplantation, and situation reconfiguration, which has in turn helped to develop more common ground on ethnic identification. With a detailed discussion on the topic, the paper also makes it clear that the western ＂nation-state＂ theory dwelt upon by some Chinese scholars with great relish is inapplicable to China.
Tracking cohesive subgroups over time in inferred social networks
Chin, Alvin; Chignell, Mark; Wang, Hao
2010-04-01
As a first step in the development of community trackers for large-scale online interaction, this paper shows how cohesive subgroup analysis using the Social Cohesion Analysis of Networks (SCAN; Chin and Chignell 2008) and Data-Intensive Socially Similar Evolving Community Tracker (DISSECT; Chin and Chignell 2010) methods can be applied to the problem of identifying cohesive subgroups and tracking them over time. Three case studies are reported, and the findings are used to evaluate how well the SCAN and DISSECT methods work for different types of data. In the largest of the case studies, variations in temporal cohesiveness are identified across a set of subgroups extracted from the inferred social network. Further modifications to the DISSECT methodology are suggested based on the results obtained. The paper concludes with recommendations concerning further research that would be beneficial in addressing the community tracking problem for online data.
Discrete neurocognitive subgroups in fully or partially remitted bipolar disorder
Jensen, Johan Høy; Knorr, Ulla; Vinberg, Maj
2016-01-01
BACKGROUND: Neurocognitive impairment in remitted patients with bipolar disorder contributes to functional disabilities. However, the pattern and impact of these deficits are unclear. METHODS: We pooled data from 193 fully or partially remitted patients with bipolar disorder and 110 healthy...... controls. Hierarchical cluster analysis was conducted to determine whether there are discrete neurocognitive subgroups in bipolar disorder. The pattern of the cognitive deficits and the characteristics of patients in these neurocognitive subgroups were examined with analyses of covariance and least...... significance difference pairwise comparison. RESULTS: Three discrete neurocognitive subgroups were detected: one that was cognitively intact (46.1%), one that was selectively impaired with deficits in processing speed (32.6%), and one that was globally impaired across verbal learning, working memory...
Young children with language difficulties: a dimensional approach to subgrouping.
Jansen, Rianne; Ceulemans, Eva; Grauwels, Jolien; Maljaars, Jarymke; Zink, Inge; Steyaert, Jean; Noens, Ilse
2013-11-01
A dimensional approach was used to create bottom-up constructed subgroups that captured the behavioral heterogeneity in 36 Dutch-speaking children with language difficulties. Four subgroups were delineated based upon differences in cognitive ability, symbol understanding, joint attention and autism spectrum disorder related characteristics. Children with a different developmental disorder were found within a single cluster. Therefore, the results of this study suggest that bottom-up constructed subgroups might capture the heterogeneous behavioral profiles of young children with developmental difficulties in a more meaningful way. Furthermore, joint attention and symbol understanding seem important skills to assess in young children presenting with language difficulties. Copyright © 2013 Elsevier Ltd. All rights reserved.
Clinical symptoms and symptom signatures of Alzheimer's disease subgroups.
Iqbal, Khalid; Flory, Michael; Soininen, Hilkka
2013-01-01
Alzheimer's disease (AD) is a multifactorial disorder that involves several different mechanisms. Over 99% of AD patients suffer from the sporadic form of the disease. Based on cerebrospinal fluid (CSF) levels of amyloid-β (Aβ)(1-42), total tau, and ubiquitin--the markers associated with the histopathological hallmarks of the disease (Aβ plaques and abnormally hyperphosphorylated neurofibrillary tangles)--previous studies identified five subgroups of AD. Here we report the potential diagnostic predictive value of hallucination, hypokinesia, paranoia, rigidity, and tremors in aged individuals for AD and differences in the prevalence of these symptoms in the CSF marker-based subgroups of the disease. Analysis of 196 clinically diagnosed AD or Alzheimer with Lewy body, and 75 non-AD neurological and non-neurological control cases, all from a single center, showed that the presence of hallucination, hypokinesia, paranoia, rigidity, or tremors individually, or the presence of any of these, could diagnose AD with sensitivities and specificities of 14% and 99%; 30% and 99%; 15% and 99%; 16% and 100%; 16% and 96%; and 47% and 92%, respectively. The pattern of the prevalence of the above symptoms varied from AD subgroup to subgroup. Presence of any of these symptoms, as well as presence of each individual symptom except tremors, significantly differentiated AD subgroups from the predominantly control cluster. These findings encourage the exploration of hallucination, hypokinesia, paranoia, rigidity, and tremors in identifying various subgroups of AD for stratification of patients for clinical trials to develop therapeutic drugs. This study is for the special issue of the Journal of Alzheimer's Disease honoring Inge Grundke-Iqbal who made several seminal contributions in AD research.
Eirikstoft, Heidi; Kongsted, Alice
2014-01-01
Sub-grouping of low back pain (LBP) is believed to improve prediction of prognosis and treatment effects. The objectives of this study were: (1) to examine whether chiropractic patients could be sub-grouped according to an existing pathoanatomically-based classification system, (2) to describe...... relevance of the classification system should be investigated by testing its value as a prognostic factor or a treatment effect modifier. It is recommended that this classification system be combined with psychological and social factors if it is to be useful....
Identifying subgroups of patients using latent class analysis
Nielsen, Anne Mølgaard; Kent, Peter; Hestbæk, Lise
2017-01-01
(activity, contextual factors, pain, participation, physical impairment and psychology) (first stage) as the variables entered into the second stage of the two-stage LCA to identify patient subgroups. The description of the results of the single-stage and two-stage LCA was based on a combination...... identified similar, but not identical, patient subgroups characterised by (i) mild intermittent LBP, (ii) recent severe LBP and activity limitations, (iii) very recent severe LBP with both activity and participation limitations, (iv) work-related LBP, (v) LBP and several negative consequences and (vi) LBP...
Group Cooperation in Outdoor Education
Matthews, Bruce E.
1978-01-01
Utilizing the Beatles' Yellow Submarine fantasy (e.g., the Blue Meanies), this outdoor education program is designed for sixth graders and special education students. Activities developed at the Cortland Resident Outdoor Education Camp include a series of group stress/challenge activities to be accomplished by everyone in the group, as a group.…
New characterizations of finite supersoluble groups
Alexander; N; SKIBA
2008-01-01
Let A be a subgroup of a group G and X a nonempty subset of G.A is called an X- semipermutable subgroup of G if A has a supplement T in G such that for every subgroup T1 of T there exists an clement x∈X such that ATix=TixA.On the basis of this concept we obtain some new characterizations of finite supersoluble groups.
New characterizations of finite supersoluble groups
LI BaoJun; Alexander N SKIBA
2008-01-01
Let A be a subgroup of a group G and X a nonempty subset of G. A is called an X-semipermutable subgroup of G if A has a supplement T in G such that for every subgroup T1 of T there exists an element x ∈ X such that AT1x=T1xA. On the basis of this concept we obtain some new characterizations of finite supersoluble groups.
Antibody response to 17D yellow fever vaccine in Ghanaian infants.
Osei-Kwasi, M; Dunyo, S K; Koram, K A; Afari, E A; Odoom, J K; Nkrumah, F K
2001-01-01
To assess the seroresponses to yellow fever vaccination at 6 and 9 months of age; assess any possible adverse effects of immunization with the 17D yellow fever vaccine in infants, particularly at 6 months of age. Four hundred and twenty infants who had completed BCG, OPV and DPT immunizations were randomized to receive yellow fever immunization at either 6 or 9 months. A single dose of 0.5 ml of the reconstituted vaccine was administered to each infant by subcutaneous injection. To determine the yellow fever antibody levels of the infants, each donated 1 ml whole blood prior to immunization and 3 months post-immunization. Each serum sample was titred on Vero cells against the vaccine virus. The most common adverse reactions reported were fever, cough, diarrhoea and mild reactions at the inoculation site. The incidences of adverse reactions were not statistically different in both groups. None of the pre-immunization sera in both age groups had detectable yellow fever antibodies. Infants immunized at 6 months recorded seroconversion of 98.6% and those immunized at 9 months recorded 98% seroconversion. The GMT of their antibodies were 158.5 and 129.8, respectively. The results indicate that seroresponses to yellow fever immunization at 6 and 9 months as determined by seroconversion and GMTs of antibodies are similar. The findings of good seroresponses at 6 months without significant adverse effects would suggest that the 17D yellow fever vaccine could be recommended for use in children at 6 months in outbreak situations or in high risk endemic areas.
Latino Male Ethnic Subgroups: Patterns in College Enrollment and Degree Completion
Ponjuan, Luis; Palomin, Leticia; Calise, Angela
2015-01-01
This chapter examines Latino male ethnic subgroups and their college enrollment and degree completion patterns. The chapter also offers recommendations to improve Latino male ethnic subgroups' educational achievement.
Effects of substituting yellow corn for sorghum in geese diets on magret and foie gras quality.
Arroyo, J; Auvergne, A; Dubois, J P; Lavigne, F; Bijja, M; Bannelier, C; Manse, H; Fortun-Lamothe, L
2013-09-01
The aim of this trial was to study the effects of substitution of yellow corn with sorghum during the growing-finishing (G period), overfeeding (O period), or both periods on magret and foie gras quality in geese. In total, 260 ganders were divided into 4 groups (65 birds in each) differing in the cereal (yellow corn or sorghum) included in the diet given during the G and the O periods, using a 2 × 2 factorial arrangement of treatments. The groups differed in the nature of the cereal in the diet offered to birds between 44 and 104 d of age (G period: a diet containing 500 g of sorghum/kg (SS and SC groups) or a diet containing 500 g of yellow corn/kg (CS and CC groups). The groups differed also in the diet offered to birds between 105 and 120 d of age (O period): 967 g of yellow corn/kg (SC and CC groups) or 965 g of sorghum/kg (SS and CS groups). At the end of the O period, the birds were slaughtered after 10 h of fasting to measure foie gras and breast muscle weight, color, and chemical composition. The mortality in the SC group was higher (P foie gras that were heavier 984 vs. 885 g, in CS+SS vs. CC+SC groups, respectively; P foie gras, but altered its color to a paler yellow. In contrast, a substitution during the G period only (SC group) resulted in increased mortality during the O period.
Eirikstoft, Heidi; Kongsted, Alice
2014-01-01
reducible disc syndromes followed by facet joint pain, dysfunction and sacroiliac (SI)-joint pain. Classification was inconclusive in 5% of the patients. Differences in pain, activity limitation, and psychological factors were small across subgroups. Within 10 days, 82% were reported to belong to the same......Sub-grouping of low back pain (LBP) is believed to improve prediction of prognosis and treatment effects. The objectives of this study were: (1) to examine whether chiropractic patients could be sub-grouped according to an existing pathoanatomically-based classification system, (2) to describe...... patient characteristics within each subgroup, and (3) to determine the proportion of patients in whom clinicians considered the classification to be unchanged after approximately 10 days. A cohort of 923 LBP patients was included during their first consultation. Patients completed an extensive...
Detection of Problem Gambler Subgroups Using Recursive Partitioning
Markham, Francis; Young, Martin; Doran, Bruce
2013-01-01
The multivariate socio-demographic risk factors for problem gambling have been well documented. While this body of research is valuable in determining risk factors aggregated across various populations, the majority of studies tend not to specifically identify particular subgroups of problem gamblers based on the interaction between variables. The…
Subgroup analyses of clinical effectiveness to support health technology assessments.
Paget, Marie-Ange; Chuang-Stein, Christy; Fletcher, Christine; Reid, Carol
2011-01-01
Subgroup analysis is an integral part of access and reimbursement dossiers, in particular health technology assessment (HTA), and their HTA recommendations are often limited to subpopulations. HTA recommendations for subpopulations are not always clear and without controversies. In this paper, we review several HTA guidelines regarding subgroup analyses. We describe good statistical principles for subgroup analyses of clinical effectiveness to support HTAs and include case examples where HTA recommendations were given to subpopulations only. Unlike regulatory submissions, pharmaceutical statisticians in most companies have had limited involvement in the planning, design and preparation of HTA/payers submissions. We hope to change this by highlighting how pharmaceutical statisticians should contribute to payers' submissions. This includes early engagement in reimbursement strategy discussions to influence the design, analysis and interpretation of phase III randomized clinical trials as well as meta-analyses/network meta-analyses. The focus on this paper is on subgroup analyses relating to clinical effectiveness as we believe this is the first key step of statistical involvement and influence in the preparation of HTA and reimbursement submissions.
Practical Algorithms for Subgroup Detection in Covert Networks
Memon, Nasrullah; Wiil, Uffe Kock; Qureshi, Pir Abdul Rasool
2010-01-01
In this paper, we present algorithms for subgroup detection and demonstrated them with a real-time case study of USS Cole bombing terrorist network. The algorithms are demonstrated in an application by a prototype system. The system finds associations between terrorist and terrorist organisations...
Gonzalez-Sanchez, Jon
2010-01-01
Let $w = w(x_1,..., x_n)$ be a word, i.e. an element of the free group $F =$ on $n$ generators $x_1,..., x_n$. The verbal subgroup $w(G)$ of a group $G$ is the subgroup generated by the set $\\{w (g_1,...,g_n)^{\\pm 1} | g_i \\in G, 1\\leq i\\leq n \\}$ of all $w$-values in $G$. We say that a (finite) group $G$ is $w$-maximal if $|G:w(G)|> |H:w(H)|$ for all proper subgroups $H$ of $G$ and that $G$ is hereditarily $w$-maximal if every subgroup of $G$ is $w$-maximal. In this text we study $w$-maximal and hereditarily $w$-maximal (finite) groups.
Yellow Nail Syndrome - a Case Report
Paravina Mirjana
2015-06-01
Full Text Available Yellow nail syndrome is a rare disease of unknown etiology. It is clinically characterized by a triad of yellow nails, lymphedema at one or more sites, and chronic respiratory disease (bronchitis, bronchiectasis and rhinosinusitis. All nails may be affected, but some may be spared. The nail plates are yellowish green, thickened, occasionally with transverse ridging and onycholysis, with increased longitudinal and transversal over-curvature, with partial or complete separation of the nail plate from the nail bed, without lunula and cuticle and slow nail growth rate. The lymphedema is usually peripheral, affecting the lower limbs, or in the form of pleural effusion.
Differences in Psychosocial Predictors of Obesity Among LGBT Subgroups.
Warren, Jacob C; Smalley, K Bryant; Barefoot, K Nikki
2016-08-01
The purpose of the current study was to examine the overall presence of and differences in rates of overweight/obesity among a large, nationally diverse sample of lesbian, gay, bisexual, transgender (LGBT)-identified individuals (i.e., cisgender lesbians, cisgender gay men, cisgender bisexual women, cisgender bisexual men, transgender women, and transgender men) and to identify specific psychosocial predictors of obesity within each of the six LGBT subgroups. A total of 2702 LGBT-identified participants participated in the online study. Participants completed a series of demographic questions (including weight and height) and the Depression Anxiety Stress Scale 21. The percentage of participants who were overweight/obese did not differ significantly across LGBT subgroups, with 61.1% of the total sample being overweight/obese. However, the percentage of participants who self-reported body mass indexes in the obese range differed significantly across the six LGBT subgroups, with the highest prevalence in transgender men (46.0%). In addition, the predictors of obesity varied by subgroup, with age a significant predictor for cisgender lesbians, cisgender gay men, and cisgender bisexual women, relationship status for cisgender bisexual women, employment status for both cisgender gay men and cisgender bisexual women, education level for cisgender lesbians, and depression, anxiety, and stress for cisgender gay men. None of the examined psychosocial factors emerged as predictors of obesity for cisgender bisexual men, transgender women, or transgender men. These findings suggest that there are substantial variations in the presence and predictors of obesity across LGBT subgroups that support the need for culturally tailored healthy weight promotion efforts within the LGBT community.
Frejo, L; Martin-Sanz, E; Teggi, R; Trinidad, G; Soto-Varela, A; Santos-Perez, S; Manrique, R; Perez, N; Aran, I; Almeida-Branco, M S; Batuecas-Caletrio, A; Fraile, J; Espinosa-Sanchez, J M; Perez-Guillen, V; Perez-Garrigues, H; Oliva-Dominguez, M; Aleman, O; Benitez, J; Perez, P; Lopez-Escamez, J A
2017-02-06
To define clinical subgroups by cluster analysis in patients with unilateral Meniere disease (MD) and to compare them with the clinical subgroups found in bilateral MD. A cross-sectional study with a two-step cluster analysis. A tertiary referral multicenter study. Nine hundred and eighty-eight adult patients with unilateral MD. best predictors to define clinical subgroups with potential different aetiologies. We established five clusters in unilateral MD. Group 1 is the most frequently found, includes 53% of patients, and it is defined as the sporadic, classic MD without migraine and without autoimmune disorder (AD). Group 2 is found in 8% of patients, and it is defined by hearing loss, which antedates the vertigo episodes by months or years (delayed MD), without migraine or AD in most of cases. Group 3 involves 13% of patients, and it is considered familial MD, while group 4, which includes 15% of patients, is linked to the presence of migraine in all cases. Group 5 is found in 11% of patients and is defined by a comorbid AD. We found significant differences in the distribution of AD in clusters 3, 4 and 5 between patients with uni- and bilateral MD. Cluster analysis defines clinical subgroups in MD, and it extends the phenotype beyond audiovestibular symptoms. This classification will help to improve the phenotyping in MD and facilitate the selection of patients for randomised clinical trials. © 2017 John Wiley & Sons Ltd.
Nascimento Silva, Juliana Romualdo; Camacho, Luiz Antonio B; Siqueira, Marilda M; Freire, Marcos de Silva; Castro, Yvone P; Maia, Maria de Lourdes S; Yamamura, Anna Maya Y; Martins, Reinaldo M; Leal, Maria de Luz F
2011-08-26
A randomized trial was conducted to assess the immunogenicity and reactogenicity of yellow fever vaccines (YFV) given either simultaneously in separate injections, or 30 days or more after a combined measles-mumps-rubella (MMR) vaccine. Volunteers were also randomized to YFV produced from 17DD and WHO-17D-213 substrains. The study group comprised 1769 healthy 12-month-old children brought to health care centers in Brasilia for routine vaccination. The reactogenicity was of the type and frequency expected for the vaccines and no severe adverse event was associated to either vaccine. Seroconversion and seropositivity 30 days or more after vaccination against yellow fever was similar across groups defined by YFV substrain. Subjects injected YFV and MMR simultaneously had lower seroconversion rates--90% for rubella, 70% for yellow fever and 61% for mumps--compared with those vaccinated 30 days apart--97% for rubella, 87% for yellow fever and 71% for mumps. Seroconversion rates for measles were higher than 98% in both comparison groups. Geometric mean titers for rubella and for yellow fever were approximately three times higher among those who got the vaccines 30 days apart. For measles and mumps antibodies GMTs were similar across groups. MMR's interference in immune response of YFV and YFV's interference in immune response of rubella and mumps components of MMR had never been reported before but are consistent with previous observations from other live vaccines. These results may affect the recommendations regarding primary vaccination with yellow fever vaccine and MMR.
Hodgson, Kate J; Shelton, Katherine H; van den Bree, Marianne B M
2015-09-01
Homeless young people are recognized as a very vulnerable group in terms of mental health; however, few studies in the UK have examined this. Furthermore, homeless young people represent a heterogeneous group in terms of their mental health and greater characterization could improve intervention work. The aims of this study were to examine prevalence and subtypes of psychopathology among a British sample of young homeless people and to investigate potential associations between identified typologies and a priori specified current and past experiences. In addition, the study intended to explore physical health, mental health, and housing outcomes for the different mental health subgroups. A prospective longitudinal design was used. Structured interviews including a mental health assessment were conducted with 90 young homeless people aged 16-23 years. Follow-up interviews were conducted approximately 10 and 20 months later. Cluster analysis at baseline was used to identify groups based on lifetime mental health problems. The current and lifetime incidence of mental health problems was high (88% and 93%, respectively). Three subgroups of homeless young people were identified: (1) minimal mental health issues; (2) mood, substance, and conduct disorder; and (3) post-traumatic stress disorder, mood, and anxiety issues. These groups differed with respect to follow-up indicators of change and stability of mental health status, service use, and suicide risk, but not housing outcome. Other characteristics (gender ratio, past experiences) also distinguished the subgroups. Typologies of young homeless people based on psychopathology reveal differences in lifetime and future experiences including mental health at follow-up. Identified groups could be used to tailor interventions towards differing needs. Low mood, anxiety, post-traumatic stress disorder, and psychosis are common mental health issues among young homeless people in the UK. Subgroups of young homeless people with
Residual $Z_2$ symmetries and leptonic mixing patterns from finite discrete subgroups of $U(3)$
Joshipura, Anjan S
2016-01-01
We study embedding of non-commuting $Z_2$ and $Z_m$, $m\\geq 3$ symmetries in discrete subgroups (DSG) of $U(3)$ and analytically work out the mixing patterns implied by the assumption that $Z_2$ and $Z_m$ describe the residual symmetries of the neutrino and the charged lepton mass matrices respectively. Both $Z_2$ and $Z_m$ are assumed to be subgroups of a larger discrete symmetry group $G_f$ possessing three dimensional faithful irreducible representation. The residual symmetries predict the magnitude of a column of the leptonic mixing matrix $U_{\\rm PMNS}$ which are studied here assuming $G_f$ as the DSG of $SU(3)$ designated as type C and D and large number of DSG of $U(3)$ which are not in $SU(3)$. These include the known group series $\\Sigma(3n^3)$, $T_n(m)$, $\\Delta(3n^2,m)$, $\\Delta(6n^2,m)$ and $\\Delta'(6n^2,j,k)$. It is shown that the predictions for a column of $|U_{\\rm PMNS}|$ in these group series and the C and D types of groups are all contained in the predictions of the $\\Delta(6N^2)$ groups for...
Balgobind, Brian V; Raimondi, Susana C; Harbott, Jochen; Zimmermann, Martin; Alonzo, Todd A; Auvrignon, Anne; Beverloo, H Berna; Chang, Myron; Creutzig, Ursula; Dworzak, Michael N; Forestier, Erik; Gibson, Brenda; Hasle, Henrik; Harrison, Christine J; Heerema, Nyla A; Kaspers, Gertjan J L; Leszl, Anna; Litvinko, Nathalia; Nigro, Luca Lo; Morimoto, Akira; Perot, Christine; Pieters, Rob; Reinhardt, Dirk; Rubnitz, Jeffrey E; Smith, Franklin O; Stary, Jan; Stasevich, Irina; Strehl, Sabine; Taga, Takashi; Tomizawa, Daisuke; Webb, David; Zemanova, Zuzana; Zwaan, C Michel; van den Heuvel-Eibrink, Marry M
2009-09-17
Translocations involving chromosome 11q23 frequently occur in pediatric acute myeloid leukemia (AML) and are associated with poor prognosis. In most cases, the MLL gene is involved, and more than 50 translocation partners have been described. Clinical outcome data of the 11q23-rearranged subgroups are scarce because most 11q23 series are too small for meaningful analysis of subgroups, although some studies suggest that patients with t(9;11)(p22;q23) have a more favorable prognosis. We retrospectively collected outcome data of 756 children with 11q23- or MLL-rearranged AML from 11 collaborative groups to identify differences in outcome based on translocation partners. All karyotypes were centrally reviewed before assigning patients to subgroups. The event-free survival of 11q23/MLL-rearranged pediatric AML at 5 years from diagnosis was 44% (+/- 5%), with large differences across subgroups (11% +/- 5% to 92% +/- 5%). Multivariate analysis identified the following subgroups as independent prognostic predictors: t(1;11)(q21;q23) (hazard ratio [HR] = 0.1, P = .004); t(6;11)(q27;q23) (HR = 2.2, P < .001); t(10;11)(p12;q23) (HR = 1.5, P = .005); and t(10;11)(p11.2;q23) (HR = 2.5, P = .005). We could not confirm the favorable prognosis of the t(9;11)(p22;q23) subgroup. We identified large differences in outcome within 11q23/MLL-rearranged pediatric AML and novel subgroups based on translocation partners that independently predict clinical outcome. Screening for these translocation partners is needed for accurate treatment stratification at diagnosis.
Larsen, John Christian; Nørby, Karin Kristiane; Beltoft, Vibe Meister;
.001], for which there was a request for genotoxicity data in FGE.218. Flavouring Group Evaluation 218 (FGE.218) consists of furfural [FL-no: 13.018] and seven substances structurally related to furfural, 5-methylfurfural [FL-no: 13.001], furfuryl alcohol [FL-no: 13.019] and five esters of furfuryl alcohol...... is expected to be oxidised to the alpha,beta-unsaturated aldehyde furfural. However, based on the data then available the Panel concluded that furfural is not of concern with respect to genotoxicity. Furthermore, the Panel concluded that not only furfural but also the structurally related furfuryl alcohol...... to 5-[(sulphoxy)methyl]furfural which shows genotoxic potential in vitro, 5-hydroxymethylfurfural could not be evaluated through the Procedure. Accordingly, the Panel concluded that 5-methylfurfural could not be evaluated through the Procedure either. Industry has submitted additional data on the 5...
Johnson, Gary E.
2006-10-03
This annual report is a deliverable for fiscal year 2006 (FY06) for Project 2002-077-00, Facilitation of the Estuary/Ocean Subgroup (EOS). The EOS is part of the research, monitoring, and evaluation (RME) effort the Action Agencies (Bonneville Power Administration, U.S. Army Corps of Engineers, U.S. Bureau of Reclamation) developed in response to the 2000 and 2004 Biological Opinions on operation of the Federal Columbia River Power System. The goal of the EOS project is to facilitate activities of the estuary/ocean RME subgroup as it coordinates implementation of the Estuary RME Plan. In FY06, EOS project accomplishments included: 1) subgroup meetings; 2) participation in the estuary work group of the Pacific Northwest Aquatic Monitoring Partnership; 3) project management via the project tracking system, PISCES; 4) quarterly project status reports; and 5) a major revision to the Estuary RME Plan (new version May 2006) based on comments by EOS members, the Independent Scientific Review Panel, and other reviewers. In the context of uncertainty about the direction of the federal RME due to litigation on the FCRPS Biological Opinion, FY06 activities for the EOS project resulted in expanded substantive coordination with other regional RME forums, project tracking infrastructure, and a new version of the Estuary RME Plan.
The Importance of Risk and Subgroup Analysis of Nonparticipants in a Geriatric Intervention Study
Elizabeth Rosted
2016-01-01
Full Text Available Background. A major concern in intervention studies is the generalizability of the findings due to refusal of intended participants to actually take part. In studies including ill older people the number of those declining to participate may be large and the concern is therefore relevant. Objectives. To compare patients characteristics, rates of acute readmission, and mortality after one and six months among older persons who agreed and those who declined to participate in a randomized controlled trial and to describe subgroups of nonparticipants. Design. Comparative study based on a randomized controlled trial. Setting. University hospital in the Capital Region of Denmark. Participants. Patients ≥70 years discharged home after a short Emergency Department stay. 399 were requested to participate; 271 consented, whereas 128 refused. Results. Refusers were more likely to be readmitted (p<0.001 or die (p=0.006. The largest subgroup of refusers described as “too ill” had the highest risk of readmission (OR = 3.00, 95% CI = 1.61–5.47, p=0.001 and of mortality within six months (OR = 3.50, 95% CI = 1.64–7.49, p=0.002. However, this seems not to have affected the results of our randomized study. Conclusion. We recommend that intervention studies among older people or other fragile patient groups include analysis of relevant risk and subgroup analyses of refusers.
Johnson, Gary E.; Diefenderfer, Heida L.
2007-10-10
This annual report is a deliverable for fiscal year 2007 (FY07) for Project 2002-077-00, Facilitation of the Estuary/Ocean Subgroup (EOS). The EOS is part of the research, monitoring, and evaluation (RME) effort the Action Agencies (Bonneville Power Administration, U.S. Army Corps of Engineers, U.S. Bureau of Reclamation) developed in response to responsibilities arising from the Endangered Species Act as a result of operation of the Federal Columbia River Power System (FCRPS). The goal of the EOS project is to facilitate activities of the estuary/ocean RME subgroup as it coordinates design and implementation of federal RME in the lower Columbia River and estuary. In FY07, EOS project accomplishments included 1) subgroup meetings; 2) participation in the estuary work group of the Pacific Northwest Aquatic Monitoring Partnership; 3) project management via the project tracking system, PISCES; 4) quarterly project status reports; and 5) a major revision to the Estuary RME Plan (new version September 2007) based on comments by EOS members and invited reviewers.
Johnson, Gary E.; Diefenderfer, Heida L. [Pacific Northwest National Laboratory
2007-10-10
This annual report is a deliverable for fiscal year 2007 (FY07) for Project 2002-077-00, Facilitation of the Estuary/Ocean Subgroup (EOS). The EOS is part of the research, monitoring, and evaluation (RME) effort of the Action Agencies (Bonneville Power Administration, U.S. Army Corps of Engineers, U.S. Bureau of Reclamation) developed in response to responsibilities arising from the Endangered Species Act as a result of operation of the Federal Columbia River Power System (FCRPS). The goal of the EOS project is to facilitate activities of the estuary/ocean RME subgroup as it coordinates design and implementation of federal RME in the lower Columbia River and estuary. In FY07, EOS project accomplishments included (1) subgroup meetings; (2) participation in the estuary work group of the Pacific Northwest Aquatic Monitoring Partnership; (3) project management via the project tracking system, PISCES; (4) quarterly project status reports; and (5) a major revision to the Estuary RME Plan (new version September 2007) based on comments by EOS members and invited reviewers.
Mehta, S; Rice, D; McIntyre, A; Getty, H; Speechley, M; Sequeira, K; Shapiro, A P; Morley-Forster, P; Teasell, R W
2016-01-01
Objective. The current study attempted to identify and characterize distinct CP subgroups based on their level of dispositional personality traits. The secondary objective was to compare the difference among the subgroups in mood, coping, and disability. Methods. Individuals with chronic pain were assessed for demographic, psychosocial, and personality measures. A two-step cluster analysis was conducted in order to identify distinct subgroups of patients based on their level of personality traits. Differences in clinical outcomes were compared using the multivariate analysis of variance based on cluster membership. Results. In 229 participants, three clusters were formed. No significant difference was seen among the clusters on patient demographic factors including age, sex, relationship status, duration of pain, and pain intensity. Those with high levels of dispositional personality traits had greater levels of mood impairment compared to the other two groups (p personality traits significantly correlated with impaired mood and coping. Use of pharmacological treatment alone may not be successful in improving clinical outcomes among these individuals. Instead, a more comprehensive treatment involving psychological treatments may be important in managing the personality traits that interfere with recovery.
Johnson, Gary E.; Diefenderfer, Heida L. [Pacific Northwest National Laboratory
2007-10-10
This annual report is a deliverable for fiscal year 2007 (FY07) for Project 2002-077-00, Facilitation of the Estuary/Ocean Subgroup (EOS). The EOS is part of the research, monitoring, and evaluation (RME) effort of the Action Agencies (Bonneville Power Administration, U.S. Army Corps of Engineers, U.S. Bureau of Reclamation) developed in response to responsibilities arising from the Endangered Species Act as a result of operation of the Federal Columbia River Power System (FCRPS). The goal of the EOS project is to facilitate activities of the estuary/ocean RME subgroup as it coordinates design and implementation of federal RME in the lower Columbia River and estuary. In FY07, EOS project accomplishments included (1) subgroup meetings; (2) participation in the estuary work group of the Pacific Northwest Aquatic Monitoring Partnership; (3) project management via the project tracking system, PISCES; (4) quarterly project status reports; and (5) a major revision to the Estuary RME Plan (new version September 2007) based on comments by EOS members and invited reviewers.
Johnson, Gary E.; Diefenderfer, Heida L.
2007-10-10
This annual report is a deliverable for fiscal year 2007 (FY07) for Project 2002-077-00, Facilitation of the Estuary/Ocean Subgroup (EOS). The EOS is part of the research, monitoring, and evaluation (RME) effort the Action Agencies (Bonneville Power Administration, U.S. Army Corps of Engineers, U.S. Bureau of Reclamation) developed in response to responsibilities arising from the Endangered Species Act as a result of operation of the Federal Columbia River Power System (FCRPS). The goal of the EOS project is to facilitate activities of the estuary/ocean RME subgroup as it coordinates design and implementation of federal RME in the lower Columbia River and estuary. In FY07, EOS project accomplishments included 1) subgroup meetings; 2) participation in the estuary work group of the Pacific Northwest Aquatic Monitoring Partnership; 3) project management via the project tracking system, PISCES; 4) quarterly project status reports; and 5) a major revision to the Estuary RME Plan (new version September 2007) based on comments by EOS members and invited reviewers.
Summary of the activities of the subgroup on data acquisition and processing
Connolly, P.L.; Doughty, D.C.; Elias, J.E.
1981-01-01
A data acquisition and handling subgroup consisting of approximately 20 members met during the 1981 ISABELLE summer study. Discussions were led by members of the BNL ISABELLE Data Acquisition Group (DAG) with lively participation from outside users. Particularly large contributions were made by representatives of BNL experiments 734, 735, and the MPS, as well as the Fermilab Colliding Detector Facility and the SLAC LASS Facility. In contrast to the 1978 study, the subgroup did not divide its activities into investigations of various individual detectors, but instead attempted to review the current state-of-the-art in the data acquisition, trigger processing, and data handling fields. A series of meetings first reviewed individual pieces of the problem, including status of the Fastbus Project, the Nevis trigger processor, the SLAC 168/E and 3081/E emulators, and efforts within DAG. Additional meetings dealt with the question involving specifying and building complete data acquisition systems. For any given problem, a series of possible solutions was proposed by the members of the subgroup. In general, any given solution had both advantages and disadvantages, and there was never any consensus on which approach was best. However, there was agreement that certain problems could only be handled by systems of a given power or greater. what will be given here is a review of various solutions with associated powers, costs, advantages, and disadvantages.
On subgroups of semi-abelian varieties defined by difference equations
Chatzidakis, Zoé
2011-01-01
Consider the algebraic dynamics on a torus $T=G_m^n$ given by a matrix $M$ in $GL_n(Z)$. Assume that the characteristic polynomial of $M$ is prime to all polynomials $X^m-1$. We show that any finite equivariant map from another algebraic dynamics onto $(T,M)$ arises from a finite isogeny $T \\to T$. A similar and more general statement is shown for Abelian and semi-abelian varieties. In model-theoretic terms, our result says: Working in an existentially closed difference field, we consider a definable subgroup $B$ of a semi-abelian variety $A$; assume $B$ does not have a subgroup isogenous to $A'(F)$ for some twisted fixed field $F$, and some semi-Abelian variety $A'$. Then B with the induced structure is stable and stably embedded. This implies in particular that for any $n>0$, any definable subset of $B^n$ is a Boolean combination of cosets of definable subgroups of $B^n$. This result was already known in characteristic 0 where indeed it holds for all commutative algebraic groups ([CH]). In positive characte...
Parke, Carol S.
2016-01-01
This study provides an illustration of the ways in which schools can use intra-group analysis to identify salient factors related to achievement and to raise questions for further analysis. Previous research has analyzed data between demographic subgroups. This study, however, analyzes differences within the Black student cohort of one school…
Hong-Xia Zhang; Guang-Sheng Wu; Wei-Ling Guo
2016-01-01
Objective:To investigate the changes and significances of Th1/Th2, related cytokines and T cell subgroup in aplastic anemia(AA) patients.Methods:A total of 87 cases AA patients were chosen. They were set as observation group, and they were divided into acute group (n=21) and chronic group (n=66) according to the condition, chose another 30 cases healthy volunteers as control group, detected the Th1 cytokine interferon-γ (IFN-γ) and Th2 cytokines interleukin-4 (IL-4) with nzyme-linked immunosorbent method, detected the Th1/Th2 cells and T cells subgroup with flow cytometry instrument between groups.Results:The Th1 cells and Th1/Th2 cells in observation group were significantly higher than control group. Th1 cells and Th1/Th2 cells in acute group were significantly higher than chronic group; The IFN-γ, IL-4 and IFN-γ/IL-4 in observation group were significantly higher than that of control group, and the IFN-γ, IL-4 and IFN-γ/IL-4 in acute group were significantly higher than chronic group; The blood CD4+, CD4+/CD8+ in observation group were significantly lower than the control group, CD8+ was significantly higher than the control group, and the blood CD4+, CD4+/CD8+ in acute group were significantly lower than the chronic group, CD8+ was significantly higher than the chronic group, all the difference was statistically significant.Conclusion:T cell subgroup imbalances and Th1 migration plays the important role in the onset of AA, and may relate to a certain degree of disease state.
Hornets yellow cuticle microstructure : A photovoltaic system
Ishay, JS; Goldstein, O; Rosenzweig, E; Kalicharan, D; Jongebloed, WL
1997-01-01
This paper describes cuticular structures on the abdomen of the Oriental hornet (Vespa orientalis, Vespinae, Hymenoptera) in the region of the yellow stripes. A cross section in this region reveals the cuticle to resemble a notebook with more than 30 pages, the topmost pages (analogous to layers) be
Evolution of Modern Yellow River Delta Coast
尹延鸿; 周永青; 丁东
2004-01-01
This paper deals with the development and evolution of modem Yellow River delta and the erosion or deposition rates of its different sections. In June, 1996,Yellow Rivers terminal course was artificially turned eastwards to empty into the sea and then the 11th lobe of the modern Yellow River delta began to form. This course change may mark the beginning of the 3rd subdelta formation. As a result of that, the Yellow River delta advances towards east by north with the 1st, 2nd and 3rd subdeltas arranged in succession. Coast zone in the deltaic area is divided into 7 different sections according to their different erosion or deposition rates: the relatively stable section from Dakou River to Shunjiang Stream, the weakly retreating section from Shun jiang Stream to the Tiaohe River mouth, the strongly retreating section from the Tiaohe River mouth to the station 106, the artificially stable section due to stone dam protection from the station 106 to Gudong Oilfield, the strong deposition section from Gudong Oilfield to Dawenliu Haipu, the weakly deposition section from Dawenliu Haipu to the Zimai Stream mouth, and the stable section from the Zimai Stream mouth to the Jiaolai River mouth. It is predicted that the erosion and deposition situations of the sections will nearly remain the same in 10 years, but the retreating and silting-up rates will tend to become slower gradually. Human activities have an evident influence on the changes of the coastline.
A Hopi tradition: Yellow firing ceramics
Canouts, Veletta; Bishop, Ronald
1995-09-01
The famed Hopi yellow-ware vessels of the American southwest were not the product of any single technological variable, firing technique, clay, or temper Instead, all of these factors worked together in a technological system affected by the desires, knowledge, and effectualness of the people producing the pottery.
Enzootic transmission of yellow fever virus, Venezuela.
Auguste, Albert J; Lemey, Philippe; Bergren, Nicholas A; Giambalvo, Dileyvic; Moncada, Maria; Morón, Dulce; Hernandez, Rosa; Navarro, Juan-Carlos; Weaver, Scott C
2015-01-01
Phylogenetic analysis of yellow fever virus (YFV) strains isolated from Venezuela strongly supports YFV maintenance in situ in Venezuela, with evidence of regionally independent evolution within the country. However, there is considerable YFV movement from Brazil to Venezuela and between Trinidad and Venezuela.
Locally minimal topological groups
Außenhofer, Lydia; Chasco, María Jesús; Dikranjan, Dikran; Domínguez, Xabier
2009-01-01
A Hausdorff topological group $(G,\\tau)$ is called locally minimal if there exists a neighborhood $U$ of 0 in $\\tau$ such that $U$ fails to be a neighborhood of zero in any Hausdorff group topology on $G$ which is strictly coarser than $\\tau.$ Examples of locally minimal groups are all subgroups of Banach-Lie groups, all locally compact groups and all minimal groups. Motivated by the fact that locally compact NSS groups are Lie groups, we study the connection between local minimality and the ...
Identification of Subgroups of Women with Carpal Tunnel Syndrome with Central Sensitization.
Fernández-de-Las-Peñas, César; Fernández-Muñoz, Juan J; Navarro-Pardo, Esperanza; da-Silva-Pocinho, Ricardo F; Ambite-Quesada, Silvia; Pareja, Juan A
2016-09-01
Identification of subjects with different sensitization mechanisms can help to identify better therapeutic strategies for carpal tunnel syndrome (CTS). The aim of the current study was to identify subgroups of women with CTS with different levels of sensitization. A total of 223 women with CTS were recruited. Self-reported variables included pain intensity, function, disability, and depression. Pressure pain thresholds (PPT) were assessed bilaterally over median, ulnar, and radial nerves, C5-C6 joint, carpal tunnel, and tibialis anterior to assess widespread pressure pain hyperalgesia. Heat (HPT) and cold (CPT) pain thresholds were also bilaterally assessed over the carpal tunnel and the thenar eminence to determine thermal pain hyperalgesia. Pinch grip force between the thumb and the remaining fingers was calculated to determine motor assessment. Subgroups were determined according to the status on a previous clinical prediction rule: PPT over the affected C5-C6 joint 66 points. The ANOVA showed that women within group 1 (positive rule, n = 60) exhibited bilateral widespread pressure hyperalgesia (P < 0.001) and bilateral thermal thresholds (P < 0.001) than those within group 2 (negative rule, n = 162). Women in group 1 also exhibited higher depression than those in group 2 (P = 0.023). No differences in self-reported variables were observed. This study showed that a clinical prediction rule originally developed for identifying women with CTS who are likely to respond favorably to manual physical therapy was able to identify women exhibiting higher widespread pressure hyper-sensitivity and thermal hyperalgesia. This subgroup of women with CTS exhibiting higher sensitization may need specific therapeutic programs. © 2016 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Pfau, Doreen B; Rolke, Roman; Nickel, Ralf; Treede, Rolf-Detlef; Daublaender, Monika
2009-12-15
Some patients with myofascial pain from temporomandibular disorders (TMD) report pain in extra-trigeminal body regions. Our aim was to distinguish TMD as regional musculoskeletal pain syndrome (n=23) from a widespread pain syndrome (FMS; n=18) based on patients' tender point scores, pain drawings and quantitative sensory testing (QST) profiles. Referenced to 18 age- and gender-matched healthy subjects significant group differences for cold, pressure and pinprick pain thresholds, suprathreshold pinprick sensitivity and mechanical detection thresholds were found. Pain sensitivity in TMD patients ranged between those of FMS patients and healthy controls. The group of TMD patients was inhomogeneous with respect to their tender point count with an insensitive group (n=12) resembling healthy controls and a sensitive TMD group (n=9) resembling FMS patients. Nevertheless sensitive TMD patients did not fulfil diagnostic criteria for FMS in regard to widespread pain as shown by their pain drawings. TMD subgroups did not differ with respect to psychological parameters. The sensitive subgroup was more sensitive compared to healthy controls and to insensitive TMD patients in regard to their QST profile over all test areas as well as to their tenderness over orofacial muscles and trigeminal foramina. However, sensitive TMD patients had a short pain duration arguing against a transition from TMD to FMS over time. Data rather suggest an overlap in pathophysiology with FMS, e.g. a disturbance of central pain processing, in this subgroup of TMD patients. Those patients could be identified on the basis of their tender point count as an easy practicable screening tool.
Peter Becker-Kern
2007-11-01
This note generalizes known results concerning the existence of roots and embedding one-parameter subgroups on -adic solenoids. An explicit representation of the roots leads to the construction of two distinct rational embedding one-parameter subgroups. The results contribute to enlighten the group structure of solenoids and to point out difficulties arising in the context of the embedding problem in probability theory. As a consequence, the uniqueness of embedding of infinitely divisible probability measures on -adic solenoids is solved under a certain natural condition.
21 CFR 573.1020 - Yellow prussiate of soda.
2010-04-01
... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Yellow prussiate of soda. 573.1020 Section 573.1020 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Food Additive Listing § 573.1020 Yellow prussiate of soda. Yellow prussiate of soda...
7 CFR 28.441 - Strict Middling Yellow Stained Color.
2010-01-01
... 7 Agriculture 2 2010-01-01 2010-01-01 false Strict Middling Yellow Stained Color. 28.441 Section... Strict Middling Yellow Stained Color. Strict Middling Yellow Stained Color is color which is deeper than that of Strict Middling Tinged Color....
49 CFR 173.188 - White or yellow phosphorus.
2010-10-01
... 49 Transportation 2 2010-10-01 2010-10-01 false White or yellow phosphorus. 173.188 Section 173... Class 7 § 173.188 White or yellow phosphorus. Phosphorus, white or yellow, when offered for... pound) of phosphorus with screw-top closures; or (2) Steel drums (1A1) not over 250 L (66...
Arnbak, Bodil; Jensen, Rikke Krüger; Manniche, Claus;
2016-01-01
BACKGROUND: The aim of this study was to investigate subgroups of magnetic resonance imaging (MRI) findings for the spine and sacroiliac joints (SIJs) using latent class analysis (LCA), and to investigate whether these subgroups differ in their demographic and clinical characteristics. METHODS......: The sample included 1037 patients aged 18-40 years with persistent low back pain (LBP). LCA was applied to MRI findings of the spine and SIJs. The resulting subgroups were tested for differences in self-reported demographic and clinical characteristics. RESULTS: A five-class model was identified: Subgroup 1...... the subgroups with predominantly spinal findings (Subgroups 1-3), median age, prevalence of men, being overweight and previous LBP episodes were statistically significantly lower in Subgroup 1, higher in Subgroup 2 and highest in Subgroup 3. CONCLUSIONS: Five distinct subgroups of MRI findings in the spine...
Respiratory changes, hand fingers edema and yellow nails in a 94-year-old woman
Vitorino Modesto dos Santos
2015-10-01
Full Text Available A 94-year-old woman, with antecedent of chronic bronchitis, bronchiectasis, recurrent pneumonitis, arterial hypertension and chronic renal failure was admitted to control an episode of cardiac and respiratory insufficiency. Yellow nail changes and a tendency to pincer nails developed in her hand and toe fingers, preceded by longstanding course of respiratory diseases with pleural involvement. Laboratory tests detected moderate anemia and mildly elevated levels of urea and creatinine, thyroid function was normal. This case study is about yellow nail syndrome in the absence of ankle lymphedema, and affecting a woman of the oldest-old age group with renal failure.
A putative resistant DNA marker for wool yellowing susceptibility in sheep
Benavides M.V.
2000-01-01
Full Text Available An Australian Merino flock was screened for low (resistant and high (susceptible yellow predictive colour (YPC breeding values in order to compare extreme individuals using the differential display of mRNA technique. One differentially expressed cDNA band was visualised only in the resistant group. This band showed no identity with the DNA sequences of public databases; however, they showed short homologies with three database sequences related to transmembrane signalling functions. The use of these candidate genes as DNA markers needs to be confirmed against sheep with a wide range of susceptibility to wool yellowing to verify the results.
Auramine-o (Synthetic Yellow Cow Dung Powder) Poisoning: Rare but Fatal.
Dhadke, Shubhangi; Dhadke, Vitthal; Giram, Abhijit
2017-07-01
Cow dung known since long ago for its germicidal properties, used by Indian villagers to clean the house premises. As cow dung is not available easily, nowadays people have started using synthetic yellow coloured powder (Auramine-o) available easily in grocery shops locally known as "Morechap powder" in districts of Maharashtra. As the poisoning is rare, very few literatures are available mentioning the detailed mechanism of action, clinical presentation and complications. To study the clinical features, treatment and outcomes of synthetic yellow cow dung powder poisoning. 25 patients presenting with confirmed H/O consumption of (Auramine-o) synthetic yellow cow dung powder poisoning were studied. Patient's routine investigations BSL, RFT, LFT were done. CT brain was done whenever indicated. Synthetic yellow cow dung powder poisoning was common in young age group and females. Vomiting, respiratory depression were common symptoms. Synthetic yellow cow dung powder poisoning was needed only symptomatic treatment. It was very rare and mortality is low when treated promptly.
Satya, V K; Malathi, V G; Velazhahan, R; Rabindran, R; Jayamani, P; Alice, D
2013-01-01
Yellow mosaic disease caused by mungbean yellow mosaic virus (MYMV) belonging to the genus Begomovirus (the family Geminiviridae) is a major constraint in cultivation of grain legumes in India. The urdbean (Vigna mungo (L.) Hepper) and mungbean (Vigna radiata (L.) R. Wilczek) samples affected with yellow mosaic disease exhibits yellow mosaic symptoms along with leaf puckering and leaf distortion in Tamil Nadu. Hence the study was performed to find out if there was any association and influence of betasatellite DNA on the symptom expression of MYMV. Full length viral clones of DNA A and DNA B were obtained through rolling circle amplification from YMD infected samples and identified as mungbean yellow mosaic virus. Interestingly, betasatellite was found to associate with MYMV, and its nucleotide sequence analysis showed its 95% identity with papaya leaf curl betasatellite (DQ118862) from cowpea. The present study represents the first report about the association of papaya leaf curl betasatellite with MYMV and represents a new member of the emerging group of bipartite begomovirus associated with betasatellite DNA.
Structural determination of unknown subsidiary colors in food yellow no. 5 (Sunset yellow FCF).
Yamada, M; Nakamura, M; Yamada, T; Maitani, T; Goda, Y
1996-08-01
Major unknown subsidiary colors A (Sub A) and B (Sub B) in commercial Sunset Yellow FCF (Food Yellow No. 5 in Japan) have been isolated by preparative HPLC. Spectroscopic analyses of Sub A and Sub B revealed that their structures are trisodium salt of 6-hydroxy-7-(4-sulfophenyl)-5-(4-sulfophenylazo)-2-naphthale nesulfonic acid, and disodium salt of 3-hydroxy-4-(4-sulfophenylazo)-2-naphthalenesulfonic acid, respectively.
Practical Algorithms for Subgroup Detection in Covert Networks
Memon, Nasrullah; Wiil, Uffe Kock; Qureshi, Pir Abdul Rasool
2010-01-01
In this paper, we present algorithms for subgroup detection and demonstrated them with a real-time case study of USS Cole bombing terrorist network. The algorithms are demonstrated in an application by a prototype system. The system finds associations between terrorist and terrorist organisations...... and is capable of determining links between terrorism plots occurred in the past, their affiliation with terrorist camps, travel record, funds transfer, etc. The findings are represented by a network in the form of an Attributed Relational Graph (ARG). Paths from a node to any other node in the network indicate...... the relationships between individuals and organisations. The system also provides assistance to law enforcement agencies, indicating when the capture of a specific terrorist will more likely destabilise the terrorist network. In this paper, we discuss the important application area related to subgroups...
Pathophysiology and immunological profile of myasthenia gravis and its subgroups.
Romi, Fredrik; Hong, Yu; Gilhus, Nils Erik
2017-08-03
Myasthenia gravis (MG) is an autoimmune antibody-mediated disease characterized by muscle weakness and fatigability. It is believed that the initial steps triggering humoral immunity in MG take place inside thymic tissue and thymoma. The immune response against one or several epitopes expressed on thymic tissue cells spills over to neuromuscular junction components sharing the same epitope causing humoral autoimmunity and antibody production. The main cause of MG is acetylcholine receptor antibodies. However, many other neuromuscular junction membrane protein targets, intracellular and extracellular proteins are suggested to participate in MG pathophysiology. MG should be divided into subgroups based on clinical presentation and immunology. This includes onset age, clinical characteristics, thymic pathology and antibody profile. The immunological profile of these subgroups is determined by the antibodies present. Copyright © 2017. Published by Elsevier Ltd.
Equivariant Equipartitions: Ham Sandwich Theorems for Finite Subgroups of Spheres
Simon, Steven
2011-01-01
Equivariant "Ham Sandwich" Theorems are obtained for the finite subgroups of the unit spheres S^{d-1}, d=1,2,4. Given any F-valued mass distributions on F^n and any non-zero finite subgroup G of the unit sphere S^{d-1} in F= R, C, or H, it is shown that there exists a collection of fundamental G-regions partitioning F^n which "G-Equipartition" each of the n measures, as realized by the simultaneous vanishing of the "G-averages" of the regions' measures. Equipartition results for real measures follow, among them that any n signed mass distributions on R^{(p-1)n} can be equipartitioned by a single regular p-fan for any prime number p.
Carareto Claudia MA
2009-12-01
Full Text Available Abstract Background The Zaprionus genus shares evolutionary features with the melanogaster subgroup, such as space and time of origin. Although little information about the transposable element content in the Zaprionus genus had been accumulated, some of their elements appear to be more closely related with those of the melanogaster subgroup, indicating that these two groups of species were involved in horizontal transfer events during their evolution. Among these elements, the Gypsy and the Micropia retroelements were chosen for screening in seven species of the two Zaprionus subgenera, Anaprionus and Zaprionus. Results Screening allowed the identification of diverse Gypsy and Micropia retroelements only in species of the Zaprionus subgenus, showing that they are transcriptionally active in the sampled species. The sequences of each retroelement were closely related to those of the melanogaster species subgroup, and the most parsimonious hypothesis would be that 15 horizontal transfer events shaped their evolution. The Gypsy retroelement of the melanogaster subgroup probably invaded the Zaprionus genomes about 11 MYA. In contrast, the Micropia retroelement may have been introduced into the Zaprionus subgenus and the melanogaster subgroup from an unknown donor more recently (~3 MYA. Conclusion Gypsy and Micropia of Zaprionus and melanogaster species share similar evolutionary patterns. The sharing of evolutionary, ecological and ethological features probably allowed these species to pass through a permissive period of transposable element invasion, explaining the proposed waves of horizontal transfers.
Model Debate for the Yellow Book Learning in Islamic Boarding School
Apdoludin; Saidek, Abdul Rahim; Islami, Raisul
2016-01-01
This study aimed to determine the effect model of debate in the yellow book learning in schools to improve students' critical thinking skills so they can find a new science. This study was an experimental study with a control group. The study was conducted in classes XI Islamic Boarding School Al-Hidayah Jambi. This study uses two parallel…
Ochratoxin production and taxonomy of the yellow aspergilli (Aspergillus section Circumdati)
Visagie, C.M.; Varga, J.; Houbraken, J.
2014-01-01
Aspergillus section Circumdati or the Aspergillus ochraceus group, includes species with rough walled stipes, biseriate conidial heads, yellow to ochre conidia and sclerotia that do not turn black. Several species are able to produce mycotoxins including ochratoxins, penicillic acids, and xanthom....... The most important species regarding potential ochratoxin A contamination in agricultural products are A. ochraceus, A. steynii and A. westerdijkiae....
Effect of beta-Carotene from Yellow Ambon Banana Peel on Rat Serum Retinol Level
Suparmi Suparmi
2013-12-01
Full Text Available Vitamin A Deficiency (VAD is associated with significant morbidity and mortality from common childhood infections and is the world’s leading preventable cause of childhood blindness. Studies showed that carotenoid is one of the promissed vitamin A source. However the studies on carotenoid from yellow banana peel and its potential as a natural source of vitamin A has not been widely reported. This study was conducted to measure the blood serum retinol levels of rats after administration of β-carotene from yellow ambon banana peel. This was an experimental study with post test only control group design, with sample size of 18 rats with age 1 month, devided into 3 groups. β-carotene dose administered based on the dose of red capsules vitamin A are (200,000 doses SI for toddlers aged 12-59 months. Serum retinol levels were measured using a spectrophotometer according metide. This present study showed that the blood serum level in group treated with of β - carotene from yellow ambon banana peel (28.35 ± 1.61 mg/ dL , was significantly different (p < 0.05 from that of control group ( 22.08 ± 1.35 mg /dL . β-carotene from yellow ambon banana peel are potential as provitamin A.
Effect of β-Carotene from Yellow Ambon Banana Peel on Rat Serum Retinol Level
Suparmi
2014-06-01
Full Text Available Vitamin A Deficiency (VAD is associated with significant morbidity and mortality from common childhood infections and is the world’s leading preventable cause of childhood blindness. Studies showed that carotenoid is one of the promissed vitamin A sources. However the studies on carotenoid from yellow banana peel and its potential as a natural source of vitamin A has not been widely reported. This study was conducted to measure the blood serum retinol levels of rats after administration of β-carotene from yellow ambon banana peel. This was an experimental study with post test only control group design, with sample size of 18 rats with age 1 month, devided into 3 groups. The β-carotene dose administered based on the dose of red capsules vitamin A are (200,000 doses SI for toddlers aged 12-59 months. Serum retinol levels were measured using a spectrophotometer according metide. This present study showed that the blood serum level in group treated with of β-carotene from yellow ambon banana peel (28.35 ± 1.61 mg/dL, was significantly different (p < 0.05 from that of control group (22.08 ± 1.35 mg/dL. The β-carotene from yellow ambon banana peel are potential as provitamin A.
Notes on Discrete Subgroups of Möbius Transformations
Hua Wang; Yueping Jiang; Wensheng Cao
2013-05-01
Jørgensen’s inequality gives a necessary condition for a nonelementary two generator subgroup of $SL(2,\\mathbb{C})$ to be discrete. By embedding $SL(2,\\mathbb{C})$ into $Û(1,1;\\mathbb{H})$, we obtain a new type of Jørgensen’s inequality, which is in terms of the coefficients of involved isometries. We provide an example to show that this result gives an improvement over the classical Jørgensen’s inequality.
Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology.
Walker, Steven M; Knight, Laura A; McCavigan, Andrena M; Logan, Gemma E; Berge, Viktor; Sherif, Amir; Pandha, Hardev; Warren, Anne Y; Davidson, Catherine; Uprichard, Adam; Blayney, Jaine K; Price, Bethanie; Jellema, Gera L; Steele, Christopher J; Svindland, Aud; McDade, Simon S; Eden, Christopher G; Foster, Chris; Mills, Ian G; Neal, David E; Mason, Malcolm D; Kay, Elaine W; Waugh, David J; Harkin, D Paul; Watson, R William; Clarke, Noel W; Kennedy, Richard D
2017-10-01
Approximately 4-25% of patients with early prostate cancer develop disease recurrence following radical prostatectomy. To identify a molecular subgroup of prostate cancers with metastatic potential at presentation resulting in a high risk of recurrence following radical prostatectomy. Unsupervised hierarchical clustering was performed using gene expression data from 70 primary resections, 31 metastatic lymph nodes, and 25 normal prostate samples. Independent assay validation was performed using 322 radical prostatectomy samples from four sites with a mean follow-up of 50.3 months. Molecular subgroups were identified using unsupervised hierarchical clustering. A partial least squares approach was used to generate a gene expression assay. Relationships with outcome (time to biochemical and metastatic recurrence) were analysed using multivariable Cox regression and log-rank analysis. A molecular subgroup of primary prostate cancer with biology similar to metastatic disease was identified. A 70-transcript signature (metastatic assay) was developed and independently validated in the radical prostatectomy samples. Metastatic assay positive patients had increased risk of biochemical recurrence (multivariable hazard ratio [HR] 1.62 [1.13-2.33]; p=0.0092) and metastatic recurrence (multivariable HR=3.20 [1.76-5.80]; p=0.0001). A combined model with Cancer of the Prostate Risk Assessment post surgical (CAPRA-S) identified patients at an increased risk of biochemical and metastatic recurrence superior to either model alone (HR=2.67 [1.90-3.75]; p<0.0001 and HR=7.53 [4.13-13.73]; p<0.0001, respectively). The retrospective nature of the study is acknowledged as a potential limitation. The metastatic assay may identify a molecular subgroup of primary prostate cancers with metastatic potential. The metastatic assay may improve the ability to detect patients at risk of metastatic recurrence following radical prostatectomy. The impact of adjuvant therapies should be assessed in
Neurocognitive performance as an endophenotype for mood disorder subgroups.
Merikangas, Alison K; Cui, Lihong; Calkins, Monica E; Moore, Tyler M; Gur, Ruben C; Gur, Raquel E; Merikangas, Kathleen R
2017-06-01
There is growing evidence that neurocognitive function may be an endophenotype for mood disorders. The goal of this study is to examine the specificity and familiality of neurocognitive functioning across the full range of mood disorder subgroups, including Bipolar I (BP-I), Bipolar II (BP-II), Major Depressive Disorders (MDD), and controls in a community-based family study. A total of 310 participants from 137 families with mood spectrum disorders (n=151) and controls (n=159) completed the University of Pennsylvania's Computerized Neurocognitive Battery (CNB) that assessed the accuracy and speed of task performance across five domains. Mixed effects regression models tested association and familiality. Compared to those without mood disorders, participants with BP-I had increased accuracy in complex cognition, while participants with MDD were more accurate in emotion recognition. There was also a significant familial association for accuracy of complex cognition. Mood disorder subgroups did not differ in performance speed in any of the domains. The small number of BP-I cases, and family size limited the statistical power of these analyses, and the cross-sectional assessment of neurocognitive function precluded our ability to determine whether performance precedes or post dates onset of disorder. This is one of the few community-based family studies of potential neurocognitive endophenotypes that includes the full range of mood disorder subgroups. There were few differences in neurocognitive function except enhanced accuracy in specific domains among those with BP-I and MDD. The differential findings across specific mood disorder subgroups substantiate their heterogeneity in other biologic and endophenotypic domains. Copyright © 2017 Elsevier B.V. All rights reserved.
Flavonoids in white and yellow perianths and yellow anthers of tulips (Tulipa gesneriana L.
Marcin Horbowicz
2013-12-01
Full Text Available The content of flavonoids in white and yellow perianths and yellow anthers of a few tulip cultivars were determined at the stage of full flowering. To analyses of flavonols a HPLC method was used. In anthers (yellow of all analyzed cultivars (Oscar, Pax, Profesor Wóycicki, Biała Dama, White Virgin, Calypso, Diana high content of quercetin (2,35 - 6,01 mg·g-1 F.W., kaempferol (1,09 - 9,47 mg·g-1 F.W. and apigenin (1,34 - 8,24 mg·g-1 F.W. was found. In analyzed white perianth of cvs. Oscar and White Virgin also high content of quercetin (1,3 - 1,80 mg·g-1 F.W. and kaempferol (1,90 mg·g-1 F.W. was documented and only traces of apigenin was found. In the yellow perianth of cv. Profesor Wóycicki the level of quercetin and kaempferol was much lower than in perianth of cvs. Oscar and White Virgin, and apigenin was absent. Thus, yellow anthers and white and yellow perianth of tulip cultivars are a rich source of flavonols.
Han, Guang-Xuan; Li, Yun-Zhao; Yu, Jun-Bao; Xu, Jing-Wei; Wang, Guang-Mei; Zhang, Zhi-Dong; Mao, Pei-Li; Liu, Yu-Hong
2011-02-01
Based on the 23 sheets of remote sensing images from 1976 to 2009, in combining with the water and sediment data from Lijin station and the annual precipitation data of Yellow River Basin from 1976 to 2008, this paper quantitatively analyzed the features of water and sediment discharge from Yellow River, and the evolution process of Yellow River Delta and related driving mechanisms. In 1976-2008, the annual runoff and the annual sediment discharge into sea changed largely and frequently, but overall, presented a decreasing trend. Since the course of the Yellow River changed its direction to Qingshui channel in 1976, the Delta coastline and area were generally in a silting-up state. The evolution process of the Delta could be approximately divided into three stages, i.e., 1976-1985, 1986-1995, and 1996-2009, and the increasing rate of the Delta decreased with the stages. The coastline and area of the Delta were significantly exponentially correlated to the sediment accumulated at Lijin station, and the inter-annual variation of the precipitation of the Yellow River Basin had a strong correlation with that of the sediment at Lijin station, suggesting that the annual variation of the precipitation in Yellow River Basin was the main factor affecting the runoff and sediment discharge into sea.
Photocatalytic Decolourization of Direct Yellow 9 on Titanium and Zinc Oxides
Elżbieta Regulska
2013-01-01
Full Text Available The photodecolourization of Direct Yellow 9, a member of the group of azo dyes which are commonly used in the various branches of the industry, was investigated. The photostability of this dye was not previously examined. Photocatalytic degradation method was evaluated. Solar simulated light (E=500 W/m2, titanium dioxide, and zinc oxide were used as irradiation source and photocatalysts, respectively. Kinetic studies were performed on a basis of a spectrophotometric method. Degradation efficiency was assessed by applying high performance liquid chromatography. Disappearance of a dye from titanium dioxide and zinc oxide surfaces after degradation was confirmed by thermogravimetry and Raman microscopy. Direct Yellow 9 was found to undergo the photodegradation with approximately two times higher efficiency when zinc oxide was applied in comparison with titanium dioxide. A simple and promising way to apply the photocatalytic removal of Direct Yellow 9 in titanium dioxide and zinc oxide suspensions was presented.
Vanheel, H; Carbone, F; Valvekens, L; Simren, M; Tornblom, H; Vanuytsel, T; Van Oudenhove, L; Tack, J
2017-01-01
The Rome III criteria proposed to subdivide functional dyspepsia (FD) into a postprandial distress syndrome (PDS) group, characterized by the presence of postprandial fullness and/or early satiety, and an epigastric pain syndrome (EPS) group, characterized by the presence of epigastric pain and/or epigastric burning. It has been suggested that different pathophysiological mechanisms underlie the symptom presentations in these subgroups that might determine treatment choices. The aim of this study was to investigate the prevalence of gastric sensorimotor dysfunction in the PDS, EPS, and overlap groups and to evaluate potential differential associations with dyspeptic symptom scores. Consecutive FD patients fulfilling Rome III criteria were recruited and they scored frequency of dyspeptic symptoms (postprandial fullness, early satiety, nausea, bloating, epigastric pain, and epigastric burning) over the past 3 months (0-5; 1=once a month or less, 2=two or three times a month, 3=once a week, 4=several times a week, 5=every day). The cumulative symptom score was calculated by adding up the score of these dyspeptic symptoms. Based on these symptom scores, the patients were subdivided into subgroups according to the Rome III consensus: (i) PDS, characterized by postprandial fullness and/or early satiety at least several times a week, (ii) EPS, characterized by epigastric pain and/or epigastric burning at least once a week, and (iii) overlap, fulfilling the criteria for both PDS and EPS. Gastric sensitivity and gastric accommodation were measured using barostat testing, and solid gastric emptying was determined using the [(14)C]octanoate breath test. A total of 560 FD patients (165 men, age 41.8±0.7 years) were classified into PDS (n=131), EPS (n=50), and overlap (n=379) groups. The prevalence of gastric hypersensitivity, impaired gastric accommodation, and delayed gastric emptying were 37%, 37%, and 23%, respectively, without any differential distribution in Rome III
Cornelia M Hooper
Full Text Available Medulloblastoma is the most common form of malignant paediatric brain tumour and is the leading cause of childhood cancer related mortality. The four molecular subgroups of medulloblastoma that have been identified - WNT, SHH, Group 3 and Group 4 - have molecular and topographical characteristics suggestive of different cells of origin. Definitive identification of the cell(s of origin of the medulloblastoma subgroups, particularly the poorer prognosis Group 3 and Group 4 medulloblastoma, is critical to understand the pathogenesis of the disease, and ultimately for the development of more effective treatment options. To address this issue, the gene expression profiles of normal human neural tissues and cell types representing a broad neuro-developmental continuum, were compared to those of two independent cohorts of primary human medulloblastoma specimens. Clustering, co-expression network, and gene expression analyses revealed that WNT and SHH medulloblastoma may be derived from distinct neural stem cell populations during early embryonic development, while the transcriptional profiles of Group 3 and Group 4 medulloblastoma resemble cerebellar granule neuron precursors at weeks 10-15 and 20-30 of embryogenesis, respectively. Our data indicate that Group 3 medulloblastoma may arise through abnormal neuronal differentiation, whereas deregulation of synaptic pruning-associated apoptosis may be driving Group 4 tumorigenesis. Overall, these data provide significant new insight into the spatio-temporal relationships and molecular pathogenesis of the human medulloblastoma subgroups, and provide an important framework for the development of more refined model systems, and ultimately improved therapeutic strategies.
Hashem, Mohamed M; Atta, Attia H; Arbid, Mahmoud S; Nada, Somaia A; Asaad, Gihan Farag
2010-06-01
The use of food dyes is at least controversial because they are only of essential role. Moreover many of them have been related to health problems mainly in children that are considered a very vulnerable group. This study was carried out to investigate the effect of oral administration of Amaranth, Sunset Yellow and Curcumin for 4 weeks at doses of 47, 315 and 157.5 mg/kg b. wt. and after 2 weeks all animals were immunostimulated by intra peritoneal injection of sheep RBCs 10% (1 ml/rat). Body weight, relative body weight, total and differential leukocytes count, mononuclear cell count, delayed hypersensitivity, total protein and serum fractions were determined. Results revealed that oral administration of Amaranth, Sunset Yellow and Curcumin did not affect the body weight gain or the spleen weight. On the other hand Sunset Yellow and Curcumin significantly decreased the weight of thymus gland of the rats. Total leukocyte count were not affected while Amaranth and Curcumin-treated rats revealed a significant decrease in neutrophiles and monocytes and a compensatory increase in lymphocytes. Moreover, oral administration of Sunset Yellow revealed a significant decrease in monocyte percent. Amaranth, Sunset Yellow and Curcumin significantly decreased the delayed hyper sensitivity. Total serum protein, albumin, total globulin and albumin/globulin (A/G) ratio were not affected by administration of the colouring agents. Oral administration of Amaranth increases the density of albumin band. On the other hand oral administration of Curcumin decreases the density of the albumin band. Oral administration of any of the tested colouring agents did not change the density of globulin region as compared to control group. In conclusion we found that both synthetic (Amaranth and Sunset Yellow) and natural (Curcumin) colouring agents used at doses up to 10 times the acceptable daily intake exerted a depressing effect on the cellular but not humoral immune response.
When Do the Fibonacci Invertible Classes Modulo M Form a Subgroup?
2012-06-01
When do the Fibonacci invertible classes modulo M form a subgroup? Florian Lucaa, Pantelimon Stănicăb, Aynur Yalçinerc aInstituto de Matemáticas...aynuryalciner@gmail.com Abstract In this paper, we look at the invertible classes modulo M representable as Fibonacci numbers and we ask when these classes, say...FM , form a multi- plicative group. We show that if M itself is a Fibonacci number, then M ≤ 8; if M is a Lucas number, then M ≤ 7. We also show that
Malaga German
2009-11-01
Full Text Available Abstract Background Subgroup analyses in randomized trials examine whether effects of interventions differ between subgroups of study populations according to characteristics of patients or interventions. However, findings from subgroup analyses may be misleading, potentially resulting in suboptimal clinical and health decision making. Few studies have investigated the reporting and conduct of subgroup analyses and a number of important questions remain unanswered. The objectives of this study are: 1 to describe the reporting of subgroup analyses and claims of subgroup effects in randomized controlled trials, 2 to assess study characteristics associated with reporting of subgroup analyses and with claims of subgroup effects, and 3 to examine the analysis, and interpretation of subgroup effects for each study's primary outcome. Methods We will conduct a systematic review of 464 randomized controlled human trials published in 2007 in the 118 Core Clinical Journals defined by the National Library of Medicine. We will randomly select journal articles, stratified in a 1:1 ratio by higher impact versus lower impact journals. According to 2007 ISI total citations, we consider the New England Journal of Medicine, JAMA, Lancet, Annals of Internal Medicine, and BMJ as higher impact journals. Teams of two reviewers will independently screen full texts of reports for eligibility, and abstract data, using standardized, pilot-tested extraction forms. We will conduct univariable and multivariable logistic regression analyses to examine the association of pre-specified study characteristics with reporting of subgroup analyses and with claims of subgroup effects for the primary and any other outcomes. Discussion A clear understanding of subgroup analyses, as currently conducted and reported in published randomized controlled trials, will reveal both strengths and weaknesses of this practice. Our findings will contribute to a set of recommendations to optimize
Zooplankton community structure in the Yellow Sea and East China Sea in autumn
Hongju Chen
2015-12-01
Full Text Available Abstract Study on zooplankton spatial distribution is essential for understanding food web dynamics in marine ecosystems and fishery management. Here we elucidated the composition and distribution of large mesozooplankton on the continental shelf of the Yellow Sea and East China Sea, and explored the zooplankton community structure in these water masses. Sixty vertical hauls (bottom or 200 m in deep water to surface using a ring net (diameter 0.8 m, 505-μm mesh were exploited in November 2007. The biogeographic patterns of zooplankton communities were investigated using multivariate analysis methods; copepod biodiversity was analyzed using univariate indices. Copepods and protozoans were dominate in the communities. Based on the species composition, we divided the study areas into six station groups. Significant differences in zooplankton assemblages were detected between the Yellow Sea and East China Sea. Species richness was higher in East China Sea groups than those in Yellow Sea, whereas taxonomic distinctness was higher in Yellow Sea than in East China Sea. There was a clear relationship between the species composition and water mass group.
“Real-life” inhaled corticosteroid withdrawal in COPD: a subgroup analysis of DACCORD
Vogelmeier, Claus; Worth, Heinrich; Buhl, Roland; Criée, Carl-Peter; Lossi, Nadine S; Mailänder, Claudia; Kardos, Peter
2017-01-01
Many patients with chronic obstructive pulmonary disease (COPD) receive inhaled corticosteroids (ICSs) without a clear indication, and thus, the impact of ICS withdrawal on disease control is of great interest. DACCORD is a prospective, noninterventional 2-year study in the primary and secondary care throughout Germany. A subgroup of patients were taking ICS prior to entry – 1,022 patients continued to receive ICS for 2 years; physicians withdrew ICS on entry in 236 patients. Data from these two subgroups were analyzed to evaluate the impact of ICS withdrawal. Patients aged ≥40 years with COPD, initiating or changing COPD maintenance medication were recruited, excluding patients with asthma. Demographic and disease characteristics, prescribed COPD medication, COPD Assessment Test, exacerbations, and lung function were recorded. There were few differences in baseline characteristics; ICS withdrawn patients had shorter disease duration and better lung function, with 74.2% of ICS withdrawn patients not exacerbating, compared with 70.7% ICS-continued patients. During Year 1, exacerbation rates were 0.414 in the withdrawn group and 0.433 in the continued group. COPD Assessment Test total score improved from baseline in both groups. These data suggest that ICS withdrawal is possible with no increased risk of exacerbations in patients with COPD managed in the primary and secondary care. PMID:28203072
Ben David, Nir; Ginosar, Yuval; Meir, Ehud
2014-01-01
The analog of Lagrangians for symplectic forms over finite groups is studied, motivated by the fact that symplectic G -forms with a normal Lagrangian N◃G are in one-to-one correspondence, up to inflation, with bijective 1-cocycle data on the quotients G/N . This yields a method to construct...... groups of central type from such quotients, known as Involutive Yang–Baxter groups. Another motivation for the search of normal Lagrangians comes from a non-commutative generalization of Heisenberg liftings that require normality. Although it is true that symplectic forms over finite nilpotent groups...... always admit Lagrangians, we exhibit an example where none of these subgroups is normal. However, we prove that symplectic forms over nilpotent groups always admit normal Lagrangians if all their p -Sylow subgroups are of order less than p 8 ....
Amanda L Bradford
Full Text Available For biological populations that form aggregations (or clusters of individuals, cluster size is an important parameter in line-transect abundance estimation and should be accurately measured. Cluster size in cetaceans has traditionally been represented as the total number of individuals in a group, but group size may be underestimated if group members are spatially diffuse. Groups of false killer whales (Pseudorca crassidens can comprise numerous subgroups that are dispersed over tens of kilometers, leading to a spatial mismatch between a detected group and the theoretical framework of line-transect analysis. Three stocks of false killer whales are found within the U.S. Exclusive Economic Zone of the Hawaiian Islands (Hawaiian EEZ: an insular main Hawaiian Islands stock, a pelagic stock, and a Northwestern Hawaiian Islands (NWHI stock. A ship-based line-transect survey of the Hawaiian EEZ was conducted in the summer and fall of 2010, resulting in six systematic-effort visual sightings of pelagic (n = 5 and NWHI (n = 1 false killer whale groups. The maximum number and spatial extent of subgroups per sighting was 18 subgroups and 35 km, respectively. These sightings were combined with data from similar previous surveys and analyzed within the conventional line-transect estimation framework. The detection function, mean cluster size, and encounter rate were estimated separately to appropriately incorporate data collected using different methods. Unlike previous line-transect analyses of cetaceans, subgroups were treated as the analytical cluster instead of groups because subgroups better conform to the specifications of line-transect theory. Bootstrap values (n = 5,000 of the line-transect parameters were randomly combined to estimate the variance of stock-specific abundance estimates. Hawai'i pelagic and NWHI false killer whales were estimated to number 1,552 (CV = 0.66; 95% CI = 479-5,030 and 552 (CV = 1.09; 95% CI = 97
Assessing the freshwater distribution of yellow eel
Lasne É.
2009-04-01
Full Text Available In the global context of the decline in wild species, modeling the distribution of populations is a crucial aspect of ecological management. This can be a major challenge, especially for species, such as the European eel, that have complex life cycles, exhibit cryptic behavior, or migrate over long distances. A review of the literature suggests that eel size data could be used to assess and analyze freshwater distribution of eel. We argue that analyses based on small yellow eels (≤ 300 mm along the longitudinal course of rivers could provide a valuable tool for population monitoring. We propose a standardized catchment recruitment index and a colonization index based on the probability of occurrence (presence/absence data using logistic models for different size classes. The model developed here provides a convenient guide for assessing yellow eel stages in freshwater areas, and should have concrete applications for management of the species.
Distinct aetiopathogenesis in subgroups of functional dyspepsia according to the Rome III criteria.
Fang, Yu-Jen; Liou, Jyh-Ming; Chen, Chieh-Chang; Lee, Ji-Yuh; Hsu, Yao-Chun; Chen, Mei-Jyh; Tseng, Ping-Huei; Chen, Chien-Chuan; Chang, Chi-Yang; Yang, Tsung-Hua; Chang, Wen-Hsiung; Wu, Jeng-Yi; Wang, Hsiu-Po; Luo, Jiing-Chyuan; Lin, Jaw-Town; Shun, Chia-Tung; Wu, Ming-Shiang
2015-10-01
Whether there is distinct pathogenesis in subgroups of functional dyspepsia (FD), the postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS) remains controversial. We aimed to identify the risk factors of FD and its subgroups in the Chinese population. Patients with dyspepsia and healthy subjects who underwent gastric cancer screening were enrolled in this multicentre study from 2010 to 2012. All patients were evaluated by questionnaire, oesophagoduodenoscopy, histological examination and Helicobacter pylori tests. Subgroups of FD were classified according to the Rome III criteria. Psychiatric stress was assessed by the short form Brief Symptom Rating Scale. CagA and VacA genotypes were determined by PCR. Of 2378 patients screened for eligibility, 771 and 491 fulfilled the diagnostic criteria of uninvestigated dyspepsia and FD, respectively. 298 (60.7%) and 353 (71.9%) individuals were diagnosed with EPS and PDS, respectively, whereas 169 (34.4%) had the overlap syndrome. As compared with 1031 healthy controls, PDS and EPS shared some common risk factors, including younger age (OR 0.95; 99.5% CI 0.93 to 0.98), non-steroidal anti-inflammatory drugs (OR 6.60; 99.5% CI 3.13 to 13.90), anxiety (OR 3.41; 99.5% CI 2.01 to 5.77) and concomitant IBS (OR 6.89; 99.5% CI 3.41 to 13.94). By contrast, H. pylori (OR 1.86; 99.5% CI 1.01 to 3.45), unmarried status (OR 4.22; 99.5% CI 2.02 to 8.81), sleep disturbance (OR 2.56; 99.5% CI 1.29 to 5.07) and depression (OR 2.34; 99.5% CI 1.04 to 5.36) were associated with PDS. Moderate to severe antral atrophy and CagA positive strains were also more prevalent in PDS. Different risk factors exist among FD subgroups based on the Rome III criteria, indicating distinct aetiopathogenesis of the subdivisions that may necessitate different therapeutic strategies. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Subgrouping of risky behaviors among Iranian college students: a latent class analysis
Safiri, Saeid; Rahimi-Movaghar, Afarin; Yunesian, Masud; Sadeghi-Bazargani, Homayoun; Shamsipour, Mansour; Mansournia, Mohammad Ali; Fotouhi, Akbar
2016-01-01
Background Risky behaviors may interrupt development or cause considerable morbidity or mortality. This study’s purpose was to determine subgroups of students based on risky behaviors and assess the prevalence of risky behaviors in each of the subgroups. Participants and methods This anonymous cross-sectional study was carried out in October 2015 and November 2015, with 1,777 students from Tabriz University of Medical Sciences, through multistage random sampling method. The data were analyzed by latent class analysis. Results The prevalence rates of cigarette smoking (more than or equal to ten cigarettes), hookah use (≥1 time/month), and alcohol consumption (≥1 time/month) during the last year were 12.4% (95% confidence interval [CI]: 10.9–14.0), 11.6% (95% CI: 10.0–13.1), and 4.9% (95% CI: 3.8–5.9), respectively. The prevalence rates of illicit opioids (1.8%, 95% CI: 1.2–2.5), cannabis (1.2%, 95% CI: 0.7–1.7), methamphetamine (1.1%, 95% CI: 0.6–1.6), methylphenidate (2.5%, 95% CI: 1.7–3.2), and extramarital sex (5.5%, 95% CI: 4.5–6.6) over the last year were also estimated. Three latent classes were determined: 1) low risk; 2) cigarette and hookah smoker; and 3) high risk. It is worth mentioning that 3.7% of males and 0.4% of females were in the high risk group. Conclusion Subgrouping of college students showed that a considerable percentage of them, especially males, were classified into the high risk and cigarette and hookah smoker groups. Appropriate preventive measures that consider multiple different risky behaviors simultaneously are needed for this part of the population. PMID:27524898
Rinehart, Deborah J; Oronce, Carlos; Durfee, Michael J; Ranby, Krista W; Batal, Holly A; Hanratty, Rebecca; Vogel, Jody; Johnson, Tracy L
2016-09-14
Patients with repeated hospitalizations represent a group with potentially avoidable utilization. Recent publications have begun to highlight the heterogeneity of this group. Latent class analysis provides a novel methodological approach to utilizing administrative data to identify clinically meaningful subgroups of patients to inform tailored intervention efforts. The objective of the study was to identify clinically distinct subgroups of adult superutilizers. Retrospective cohort analysis. Adult patients who had an admission at an urban safety-net hospital in 2014 and 2 or more admissions within the preceding 12 months. Patient-level medical, mental health (MH) and substance use diagnoses, social characteristics, demographics, utilization and charges were obtained from administrative data. Latent class analyses were used to determine the number and characteristics of latent subgroups that best represented these data. In this cohort (N=1515), a 5-class model was preferred based on model fit indices, clinical interpretability and class size: class 1 (16%) characterized by alcohol use disorder and homelessness; class 2 (14%) characterized by medical conditions, MH/substance use disorders and homelessness; class 3 (25%) characterized primarily by medical conditions; class 4 (13%) characterized by more serious MH disorders, drug use disorder and homelessness; and class 5 (32%) characterized by medical conditions with some MH and substance use. Patient demographics, utilization, charges and mortality also varied by class. The overall cohort had high rates of multiple chronic medical conditions, MH, substance use disorders, and homelessness. However, the patterns of these conditions were different between subgroups, providing important information for tailoring interventions.
Rennard, Stephen I; Locantore, Nicholas; Delafont, Bruno; Tal-Singer, Ruth; Silverman, Edwin K; Vestbo, Jørgen; Miller, Bruce E; Bakke, Per; Celli, Bartolomé; Calverley, Peter M A; Coxson, Harvey; Crim, Courtney; Edwards, Lisa D; Lomas, David A; MacNee, William; Wouters, Emiel F M; Yates, Julie C; Coca, Ignacio; Agustí, Alvar
2015-03-01
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease that likely includes clinically relevant subgroups. To identify subgroups of COPD in ECLIPSE (Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints) subjects using cluster analysis and to assess clinically meaningful outcomes of the clusters during 3 years of longitudinal follow-up. Factor analysis was used to reduce 41 variables determined at recruitment in 2,164 patients with COPD to 13 main factors, and the variables with the highest loading were used for cluster analysis. Clusters were evaluated for their relationship with clinically meaningful outcomes during 3 years of follow-up. The relationships among clinical parameters were evaluated within clusters. Five subgroups were distinguished using cross-sectional clinical features. These groups differed regarding outcomes. Cluster A included patients with milder disease and had fewer deaths and hospitalizations. Cluster B had less systemic inflammation at baseline but had notable changes in health status and emphysema extent. Cluster C had many comorbidities, evidence of systemic inflammation, and the highest mortality. Cluster D had low FEV1, severe emphysema, and the highest exacerbation and COPD hospitalization rate. Cluster E was intermediate for most variables and may represent a mixed group that includes further clusters. The relationships among clinical variables within clusters differed from that in the entire COPD population. Cluster analysis using baseline data in ECLIPSE identified five COPD subgroups that differ in outcomes and inflammatory biomarkers and show different relationships between clinical parameters, suggesting the clusters represent clinically and biologically different subtypes of COPD.
Analysis of HCV genotypes from blood donors shows three new HCV type 6 subgroups exist in Myanmar.
Shinji T
2004-06-01
Full Text Available The prevalence of hepatitis C virus (HCV genotypes in Myanmar in comparison with the rest of Southeast Asia is not well known. Serum samples were obtained from 201 HCV antibody-positive volunteer blood donors in and around the Myanmar city of Yangon. Of these, the antibody titers of 101 samples were checked by serial dilution using HCV antibody PA test II and Terasaki microplate as a low-cost method. To compare antibody titers by this method and RNA identification, we also checked HCV-RNA using the Amplicor 2.0 test. Most high-titer groups were positive for HCV-RNA. Of the 201 samples, 110 were successfully polymerase chain reaction (PCR amplified. Among them, 35 (31.8% were of genotype 1, 52 (47.3% were of genotype 3, and 23 (20.9% were of type 6 variants, and phylogenetic analysis of these type 6 variants revealed that 3 new type 6 subgroups exist in Myanmar. We named the subgroups M6-1, M6-2, and M6-3. M6-1 and M6-2 were relatively close to types 8 and 9, respectively. M6-3, though only found in one sample, was a brand-new subgroup. These subtypes were not seen in Vietnam, where type 6 group variants are widely spread. These findings may be useful for analyzing how and when these subgroups were formed.
Army Science Board Ad Hoc Sub-Group Report on Energy Needs of the Army,
1980-10-01
and solar. The goal for the year 2000 is to reduce the use of natural petroleum by 75 percent and to replace natural gas with synthetic gas ( syngas ...example, one * goal states that (by 2000) syngas will replace natural gas. The Army has therefore programed efforts to Implement syngas tech- nologies at...the reactor would run at full capacity to make up for shortages and to allow the Army to meet expanded needs. The AHSG notes that such systems resolve
Weyer Sharon
2008-05-01
Full Text Available Abstract Background The relationship between health care practices' capacity for change and the results and sustainability of interventions to improve health care delivery is unclear. Methods In the setting of an intervention to increase preventive service delivery (PSD, we assessed practice capacity for change by rating motivation to change and instrumental ability to change on a one to four scale. After combining these ratings into a single score, random effects models tested its association with change in PSD rates from baseline to immediately after intervention completion and 12 months later. Results Our measure of practices' capacity for change varied widely at baseline (range 2–8; mean 4.8 ± 1.6. Practices with greater capacity for change delivered preventive services to eligible patients at higher rates after completion of the intervention (2.7% per unit increase in the combined effort score, p Conclusion Greater capacity for change is associated with a higher probability that a practice will attain and sustain desired outcomes. Future work to refine measures of this practice characteristic may be useful in planning and implementing interventions that result in sustained, evidence-based improvements in health care delivery.
Ahn, Soon-Hyun; Kim, Seong Dong; Jeong, Woo-Jin
2017-08-01
As heterogeneous findings are included in the atypia of undetermined significance (AUS)/follicular lesion of undetermined significance (FLUS) category, differing risks of malignancy in subgroups have been reported in several articles. We performed a meta-analysis of full-text publications written in English found in the Embase and PubMed databases. The 4-tiered subgroup proportion meta-analysis showed that the 95% confidence interval (95% CI) of the risk of malignancy in the cellular atypia group did not overlap with the other 3 subgroups and demonstrated a significant difference. Two-tiered analysis using the cytologic and architectural atypia groups showed that cytologic atypia group had a 2.64-fold increase in the risk of malignancy compared with the architectural atypia group. The cytologic atypia had a significantly higher risk of malignancy than the architectural atypia group, and it should be considered as a separate category. © 2017 Wiley Periodicals, Inc.
Upper bounds for reversible circuits based on Young subgroups
Abdessaied, Nabila; Soeken, Mathias; Thomsen, Michael Kirkedal;
2014-01-01
We present tighter upper bounds on the number of Toffoli gates needed in reversible circuits. Both multiple controlled Toffoli gates and mixed polarity Toffoli gates have been considered for this purpose. The calculation of the bounds is based on a synthesis approach based on Young subgroups that...... that results in circuits using a more generalized gate library. Starting from an upper bound for this library we derive new bounds which improve the existing bound by around 77%. © 2014 Elsevier B.V. All rights reserved....
Reconsideration of the temporary ADI and refined exposure assessment for Sunset Yellow FCF (E 110
EFSA Panel on Food Additives and Nutrient Sources added to food (ANS
2014-07-01
Full Text Available The Panel on Food Additives and Nutrient Sources added to Food (ANS Panel has previously provided a scientific opinion re-evaluating the safety of Sunset Yellow FCF (E 110 as a food additive in the EU and establishing a temporary acceptable daily intake (ADI of 1 mg/kg bw/day (EFSA ANS Panel, 2009. Following a request by the European Commission, the ANS Panel was asked to assess newly submitted data from a study conducted as a result of the recommendations contained in the 2009 opinion. In addition, EFSA was requested to carry out the refined exposure assessment of Sunset Yellow FCF. The new information assessed comprised an evaluation of the 28-day study report, the data considered by the Joint FAO/WHO Expert Committee on Food Additives (JECFA in its latest evaluation from 2011, and any additional toxicological information that had become available since the completion of the previous evaluation by the ANS Panel. The ANS Panel has considered that the newly submitted data from the 28-day study and the overall available toxicological database on Sunset Yellow FCF provides a basis to revise the established temporary ADI and concluded that, based on the NOAEL of 375 mg/kg bw/day from the long-term feeding study in rats and an uncertainty factor of 100, a new ADI for Sunset Yellow FCF of 4 mg/kg bw/day can be established, in agreement with the latest evaluation by JECFA. Exposure estimates for Sunset Yellow FCF based both on the currently authorised MPLs and reported use levels provided are well below the new ADI of 4 mg/kg bw/day for all population groups. Overall, the Panel concluded that, using data provided by the food industry and Member States, the reported uses and use levels of Sunset Yellow FCF (E 110 would not be of safety concern.
Multifocal blue-on-yellow visual evoked potentials in early glaucoma.
Klistorner, Alexander; Graham, Stuart L; Martins, Alessandra; Grigg, John R; Arvind, Hemamalini; Kumar, Rajesh S; James, Andrew C; Billson, Francis A
2007-09-01
To determine the sensitivity and specificity of blue-on-yellow multifocal visual evoked potentials (mfVEPs) in early glaucoma. Cross-sectional study. Fifty patients with a confirmed diagnosis of early glaucoma and 60 normal participants. Black-and-white mfVEPs and blue-on-yellow mfVEPs were recorded using the Accumap version 2.0 (ObjectiVision Pty. Ltd., Sydney, Australia). All patients also underwent achromatic standard automated perimetry (SAP). Multifocal VEP amplitude and latency values in glaucoma patients were analyzed and compared with those of the normal controls. Based on the definition of visual field defect, in the group of glaucomatous eyes with SAP defects, amplitude of blue-on-yellow mfVEP was abnormal in all 64 cases (100% sensitivity), whereas black-and-white mfVEP missed 5 cases (92.2% sensitivity). Generally, larger scotomata were noted on blue-on-yellow mfVEP compared with black-and-white mfVEP for the same eyes. There was high topographic correspondence between SAP and amplitude of blue-on-yellow mfVEP and significant (P<0.0001) correlation between them (correlation coefficient, 0.73). Abnormal amplitude was detected in 3 of 60 eyes of control subjects (95% specificity). There was, however, no correlation between visual field defect and latency delay in glaucoma patients. Although there was a significant difference between averaged latency of control and glaucoma eyes, values considerably overlapped. The blue-on-yellow mfVEP is a sensitive and specific tool for detecting early glaucoma based on amplitude analysis.
Number of patients needed to discriminate between subgroups in patient reported outcome measures
Paulsen, Aksel
2011-01-01
Background: Patient reported outcome-measures (PROs) are increasingly used in orthopedics. Information on number of patients needed in different settings is warranted. Aim: To assess the number of patients needed for different PROs to discriminate between subgroups of age, gender, and diagnosis...... with sample size calculations or by power calculations and simulated ANOVA F tests, depending on the number of groups. Results: To discriminate between gender, the least number needed to find a statistically significant difference in mean sum score in each group was 298 (OHS) while HOOS QoL required the most....... Methods: 5777 primary THA patients, operated 1‐2, 5‐6, and 10‐11 years ago. SF‐12 Health Survey (SF-12), EQ-5D, Oxford 12‐item Hip Score (OHS), and Hip dysfunction and Osteoarthritis Outcome Score (HOOS) were included. The different PRO subscales abilities to discriminate between groups were studied using...
Some Intersections and Identifications in Integral Group Rings
Ram Karan; Deepak Kumar
2002-05-01
Let be the integral group ring of a group and () its augmentation ideal. For a free group and a normal subgroup of , the intersection $I^{n+1}(F) \\cap I^n(R)$ is determined for all ≥ 1. The subgroups $F \\cap (1+ZFI(R)I(F)I(S))$ and $F \\cap (1+I(R)I^3(F))$ of are identified when and are arbitrary subgroups of .
Biswas, H.; Jie, J.; Li, Y.; Zhang, G.; Zhu, Z.-Y.; Wu, Y.; Zhang, G.-L.; Li, Y.-W.; Liu, S.M.; Zhang, J.
phytoplankton community from the Qingdao coast (NW Yellow Sea, China) was studied under different CO_{2} levels in microcosms. HPLC pigment analysis revealed the presence of diatoms as a dominant microalgal group; however, members of chlorophytes...
KELAINAN PATOLOGI PADA MENCIT DAN TIKUS DISEBABKAN ZAT WARNA RHODAMINE B DAN METANIL YELLOW
Iwan T. Budiarso
2012-09-01
Full Text Available PATHOLOGICAL LESIONS IN MICE AND RATS CAUSED BY DYESTUFFS RHODAMINE B AND METANIL YELLOW. Rhodamine B and Metanil Yellow are 2 non-edible dyestuffs which are widely used for coloring snacks and drinks in Jakarta. These substances are reportedly toxic for human beings, however no data on acute or chronic intoxications are available so far. Groups of mice and rats were fed with either Rhodamine B or Metanil Yellow. The doses of these dyestuffs varied from 0.5 mg to 1350 mg per kilogram body weight. These animals were dcvided into 3 different experimental groups, respectively acute, subacute and chronic toxicity tests. Clinical signs included discoloration of the skin and its intensity depended upon the concentration of the dyestuffs used. The body weight gain of the test animals were consistently lower than those of the controls. Some animals became agressive and cannibalism occurred. Pathological lesions consisted of unthriftiness, focal liver inflammation, hydronephrosis, hepatoma and lymphoma. Considering the results of the experiments, it is justified to warn that the wide use of Rhodamine B and Metanil Yellow for food coloring might be hazardous for human health.
Fatty acid profiles of muscle from large yellow croaker (Pseudosciaena crocea R.) of different age
Tang, Hong-gang; Chen, Li-hong; Xiao, Chao-geng; Wu, Tian-xing
2009-01-01
We investigated the fatty acid profiles of muscle from large yellow croaker (Pseudosciaena crocea R.) of different age. One- and two-year-old fish were cultured in floating net cages and sampled randomly for analysis. Moisture, protein, lipid and ash contents were determined by methods of Association of Analytical Chemist (AOAC) International. Fatty acid profile was determined by gas chromatography. Crude protein, fat, moisture and ash contents showed no significant differences between the two age groups. The contents of total polyunsaturated fatty acids and docosahexaenoic acid (DHA) were significantly higher and eicosapentaenoic acid (EPA) content was significantly lower in the two-year-old large yellow croaker than in the one-year-old (P<0.05). No significant differences were observed in the contents of total saturated fatty acids and monounsaturated fatty acids, or the ratio of n-3/n-6 fatty acids among the large yellow croakers of the two age groups. We conclude that large yellow croakers are good food sources of EPA and DHA. PMID:19235275
Molecular characterization and pathogenicity of tomato yellow leaf curl virus in China.
Zhang, Hui; Gong, Huanran; Zhou, Xueping
2009-10-01
Several tomato production regions in China were surveyed for tomato yellow leaf curl disease (TYLCD), and 31 tomato leaf samples showing TYLCD-like symptoms were collected. The partial or full-length genomes of these isolates were sequenced and tomato yellow leaf curl virus (TYLCV) was detected in Shanghai, Zhejiang, Jiangsu Shandong and Hebei provinces of China. The TYLCV isolates found in China share high sequence identity ([98%) and have more than 97% sequence identity with TYLCVIL[ IL:Reo] (X15656). Phylogenetic relationship analysis reveals that although with little genetic variability, they can form two groups and all the TYLCV isolates in China belong to the group I. An infectious clone of TYLCV-[CN:SH2] (AM282874) was constructed and agro-inoculated into Nicotiana benthamiana, N. tabacum Samsun, N. glutinosa, Solanum lycopersicum, Petunia hybrida, Cucumis sativus, Gossypium hirsutum, S. melongena, and Capsicum annuum. TYLCV-[CN:SH2] can induce severe leaf curling and stunting symptoms in these plants except C. sativus, G. hirsutum, S. melongena and C. annuum.We verified that TYLCV can trans-replicate tomato yellow leaf curl China virus DNA-b in N. benthamiana and S. lycopersicum and induced more severe symptoms with distortion and yellow vein.
KELAINAN PATOLOGI PADA MENCIT DAN TIKUS DISEBABKAN ZAT WARNA RHODAMINE B DAN METANIL YELLOW
Iwan T. Budiarso
2012-09-01
Full Text Available PATHOLOGICAL LESIONS IN MICE AND RATS CAUSED BY DYESTUFFS RHODAMINE B AND METANIL YELLOW. Rhodamine B and Metanil Yellow are 2 non-edible dyestuffs which are widely used for coloring snacks and drinks in Jakarta. These substances are reportedly toxic for human beings, however no data on acute or chronic intoxications are available so far. Groups of mice and rats were fed with either Rhodamine B or Metanil Yellow. The doses of these dyestuffs varied from 0.5 mg to 1350 mg per kilogram body weight. These animals were dcvided into 3 different experimental groups, respectively acute, subacute and chronic toxicity tests. Clinical signs included discoloration of the skin and its intensity depended upon the concentration of the dyestuffs used. The body weight gain of the test animals were consistently lower than those of the controls. Some animals became agressive and cannibalism occurred. Pathological lesions consisted of unthriftiness, focal liver inflammation, hydronephrosis, hepatoma and lymphoma. Considering the results of the experiments, it is justified to warn that the wide use of Rhodamine B and Metanil Yellow for food coloring might be hazardous for human health.
Fatty acid profiles of muscle from large yellow croaker (Pseudosciaena crocea R.) of different age
Hong-gang TANG; Li-hong CHEN; Chao-geng XIAO; Tian-xing WU
2009-01-01
We investigated the fatty acid profiles of muscle from large yellow croaker (Pseudosciaena crocea R.) of different age.One- and two-year-old fish were cultured in floating net cages and sampled randomly for analysis.Moisture,protein,lipid and ash contents were determined by methods of Association of Analytical Chemist (AOAC) International.Fatty acid profile was determined by gas chromatography.Crude protein,fat,moisture and ash contents showed no significant differences between the two age groups.The contents of total polyunsaturated fatty acids and docosahexaenoic acid (DHA) were significantly higher and eicosapentaenoic acid (EPA) content was significantly lower in the two-year-old large yellow croaker than in the one-year-old (P<0.05).No significant differences were observed in the contents of total saturated fatty acids and monounsaturated fatty acids,or the ratio of n-3/n-6 fatty acids among the large yellow croakers of the two age groups.We conclude that large yellow croakers are good food sources of EPA and DHA.
Cytotoxicity of yellow sand in lung epithelial cells
Y H Kim; K S Kim; N J Kwak; K H Lee; S A Kweon; Y Lim
2003-02-01
The present study was carried out to observe the cytotoxicity of yellow sand in comparison with silica and titanium dioxide in a rat alveolar type II cell line (RLE-6TN). Yellow sand (China Loess) was obtained from the loess layer in the Gunsu Province of China. The mean particle diameter of yellow sand was about 0.003 ± 0.001 mm. Major elements of yellow sand were Si(27.7 ± 0.6%), Al(6.01 ± 0.17%), and Ca(5.83 ± 0.23%) in that order. Silica and yellow sand significantly decreased cell viability and increased [Ca2+]i. All three particles increased the generation of H2O2. TiO2 did not change Fenton activity, while silica induced a slight increase of Fenton activity. In contrast, yellow sand induced a significant increase of Fenton activity. Silica, yellow sand and TiO2 induced significant nitrite formations in RLE-6TN cells. Silica showed the highest increase in nitrite formation, while yellow sand induced the least formation of nitrite. Silica and yellow sand increased the release of TNF-. Based on these results, we suggest that yellow sand can induce cytotoxicity in RLE-6TN cells and reactive oxygen species, Fenton activity and reactive nitrogen species might be involved in this toxicity.
Identifying homogenous subgroups for individual patient meta-analysis based on Rough Set Theory.
Gil-Herrera, Eleazar; Tsalatsanis, Athanasios; Kumar, Ambuj; Mhaskar, Rahul; Miladinovic, Branko; Yalcin, Ali; Djulbegovic, Benjamin
2014-01-01
Failure to detect and manage heterogeneity between clinical trials included in meta-analysis may lead to misinterpretation of summary effect estimates. This may ultimately compromise the validity of the results of the meta-analysis. Typically, when heterogeneity between trials is detected, researchers use sensitivity or subgroup analysis to manage it. However, both methods fail to explain why heterogeneity existed in the first place. Here we propose a novel methodology that relies on Rough Set Theory (RST) to detect, explain, and manage the sources of heterogeneity applicable to meta-analysis performed on individual patient data (IPD). The method exploits the RST relations of discernibility and indiscernibility to create homogeneous groups of patients. We applied our methodology on a dataset of 1,111 patients enrolled in 9 randomized controlled trials studying the effect of two transplantation procedures in the management of hematologic malignancies. Our method was able to create three subgroups of patients with remarkably low statistical heterogeneity values (16.8%, 0% and 0% respectively). The proposed methodology has the potential to automatize and standardize the process of detecting and managing heterogeneity in IPD meta-analysis. Future work involves investigating the applications of the proposed methodology in analyzing treatment effects in patients belonging to different risk groups, which will ultimately assist in personalized healthcare decision making.
Brusca, J S; Chinnadurai, G
1981-01-01
We have examined the functional similarity of the transforming genes for replicative functions among three different subgroups of human adenoviruses (A, B, and C), using mutant complementation as an assay. A host range deletion mutant (dl201.2) of Ad2 (nononcogenic subgroup C) lacking about 5% of the viral DNA covering two early gene blocks (E1a and E1b) involved in cellular transformation was isolated and tested for its ability to replicate in nonpermissive KB cells in the presence of Ad7 (weakly oncogenic group B) or ad12 (highly oncogenic group A). The complementation of the mutant defect was demonstrated by cleaving the viral DNA extracted from mixed infected cells or the DNA extracted from purified virions from mixed infected cells with restriction endonuclease BamHI, which produces a different cleavage pattern with the DNA of each serotype. It was found that the defects in E1a plus E1b of dl201.2 could be complemented by Ad7 and Ad12, indicating that these genes in Ad2, Ad7, and Ad12 have similar functions during productive infection. Images PMID:7277578
Elliptic curves and their torsion subgroups over number fields of type (2, 2,
无
2001-01-01
Suppose that E：y2=x(x+M)(x+N) is an elliptic curve, where M
Samuelsson, Christina; Nettelbladt, Ulrika
2004-01-01
Symptoms of prosodic problems have been found in Swedish children with language impairment at word and phrase level and possibly also at discourse level. The aim was twofold. First, to characterize a group of children with prosodic problems compared with children with normal language development. Second, to investigate the possibilities to classify subgroups of prosodic problems. A new Swedish assessment procedure for prosody that captures prosodic features at word, phrase and discourse level was used. Twenty-five children with prosodic problems and 25 children with typically developing language matched by age, gender and regional dialect participated in the study. Pretesting included tests of language comprehension, grammatical skills and oral motor skills. The difference between the experimental and control groups was highly significant in all parts of the procedure. The total score of the procedure significantly correlated with grammatical abilities measured in the pretesting procedure, but there was no correlation with the other linguistic abilities measured in the pretesting procedure. The results indicate a possible differentiation into two different subgroups, one with primarily phonetic and/or linguistic problems, the other with prosodic problems at discourse level possibly related to pragmatic problems.
Commognitive analysis of undergraduate mathematics students' first encounter with the subgroup test
Ioannou, Marios
2017-08-01
This study analyses learning aspects of undergraduate mathematics students' first encounter with the subgroup test, using the commognitive theoretical framework. It focuses on students' difficulties as these are related to the object-level and metalevel mathematical learning in group theory, and, when possible, highlights any commognitive conflicts. In the data analysis, one can identify three types of difficulties, relevant to object-level learning: namely regarding the frequently observed confusion between groups and sets, the object-level rules of visual mediators, and the object-level rules of contextual notions, such as permutations, exponentials, sets and matrices. In addition, data analysis suggests two types of difficulties, relevant to metalevel learning. The first refers to the actual proof that the three conditions of subgroup test hold, and the second is related to syntactic inaccuracies, incomplete argumentation and problematic use of visual mediators. Finally, this study suggests that there are clear links between object-level and metalevel learning, mainly due to the fact that objectification of the various relevant mathematical notions influences the endorsement of the governing metarules.
Comparative Genomics of the Listeria monocytogenes ST204 Subgroup
Fox, Edward M.; Allnutt, Theodore; Bradbury, Mark I.; Fanning, Séamus; Chandry, P. Scott
2016-01-01
The ST204 subgroup of Listeria monocytogenes is among the most frequently isolated in Australia from a range of environmental niches. In this study we provide a comparative genomics analysis of food and food environment isolates from geographically diverse sources. Analysis of the ST204 genomes showed a highly conserved core genome with the majority of variation seen in mobile genetic elements such as plasmids, transposons and phage insertions. Most strains (13/15) harbored plasmids, which although varying in size contained highly conserved sequences. Interestingly 4 isolates contained a conserved plasmid of 91,396 bp. The strains examined were isolated over a period of 12 years and from different geographic locations suggesting plasmids are an important component of the genetic repertoire of this subgroup and may provide a range of stress tolerance mechanisms. In addition to this 4 phage insertion sites and 2 transposons were identified among isolates, including a novel transposon. These genetic elements were highly conserved across isolates that harbored them, and also contained a range of genetic markers linked to stress tolerance and virulence. The maintenance of conserved mobile genetic elements in the ST204 population suggests these elements may contribute to the diverse range of niches colonized by ST204 isolates. Environmental stress selection may contribute to maintaining these genetic features, which in turn may be co-selecting for virulence markers relevant to clinical infection with ST204 isolates. PMID:28066377
Identifying and Assessing Interesting Subgroups in a Heterogeneous Population
Woojoo Lee
2015-01-01
Full Text Available Biological heterogeneity is common in many diseases and it is often the reason for therapeutic failures. Thus, there is great interest in classifying a disease into subtypes that have clinical significance in terms of prognosis or therapy response. One of the most popular methods to uncover unrecognized subtypes is cluster analysis. However, classical clustering methods such as k-means clustering or hierarchical clustering are not guaranteed to produce clinically interesting subtypes. This could be because the main statistical variability—the basis of cluster generation—is dominated by genes not associated with the clinical phenotype of interest. Furthermore, a strong prognostic factor might be relevant for a certain subgroup but not for the whole population; thus an analysis of the whole sample may not reveal this prognostic factor. To address these problems we investigate methods to identify and assess clinically interesting subgroups in a heterogeneous population. The identification step uses a clustering algorithm and to assess significance we use a false discovery rate- (FDR- based measure. Under the heterogeneity condition the standard FDR estimate is shown to overestimate the true FDR value, but this is remedied by an improved FDR estimation procedure. As illustrations, two real data examples from gene expression studies of lung cancer are provided.
Comparative Genomics of the Listeria monocytogenes ST204 Subgroup.
Fox, Edward M; Allnutt, Theodore; Bradbury, Mark I; Fanning, Séamus; Chandry, P Scott
2016-01-01
The ST204 subgroup of Listeria monocytogenes is among the most frequently isolated in Australia from a range of environmental niches. In this study we provide a comparative genomics analysis of food and food environment isolates from geographically diverse sources. Analysis of the ST204 genomes showed a highly conserved core genome with the majority of variation seen in mobile genetic elements such as plasmids, transposons and phage insertions. Most strains (13/15) harbored plasmids, which although varying in size contained highly conserved sequences. Interestingly 4 isolates contained a conserved plasmid of 91,396 bp. The strains examined were isolated over a period of 12 years and from different geographic locations suggesting plasmids are an important component of the genetic repertoire of this subgroup and may provide a range of stress tolerance mechanisms. In addition to this 4 phage insertion sites and 2 transposons were identified among isolates, including a novel transposon. These genetic elements were highly conserved across isolates that harbored them, and also contained a range of genetic markers linked to stress tolerance and virulence. The maintenance of conserved mobile genetic elements in the ST204 population suggests these elements may contribute to the diverse range of niches colonized by ST204 isolates. Environmental stress selection may contribute to maintaining these genetic features, which in turn may be co-selecting for virulence markers relevant to clinical infection with ST204 isolates.
Intragroup conflicts and efficiency of production group
Sidorenkov A.V.
2017-08-01
Full Text Available Analysis results of relationships of three levels of the conflict (interpersonal, microgroup and group on two types (the job and subject with indicators of subjectively perceived performance and social effectiveness of small groups and informal subgroups are provided. On selection of 42 work groups (N=334 employees it is established that performance efficiency of group according to the experts has inverse relation from all levels and types of the conflict, and by estimates of members of group — from two types of the microgroup conflict. The same type of effectiveness of informal subgroups on one indicator has inverse relation from the group conflict, and on another — from the interpersonal and microgroup conflict. Social effectiveness of group is connected with the interpersonal and group conflict, and informal subgroups are connected with the interpersonal and microgroup conflict. Levels and types of the conflict cause efficiency of group and subgroup not only separately, but also in a combination with each other. Six regression models, four of which display relationships at the same time of several levels and types of the conflict with performance effectiveness of group, and two — with social effectiveness of subgroup are revealed. Mediated and direct relationships of levels and types of the conflict with efficiency of group and subgroup are established.
Udeme, Nelson; Okafor, Polycarp; Eleazu, Chinedum
2015-01-01
The metabolism of yellow cassava (variety TMS 01/1368) was investigated in male albino rats fed a diet containing yellow cassava for 7 to 28 days. There were significant increases (P 0.05) in the serum total proteins of the experimental rats compared with the control. The experimental rats treated for 7, 14, 21, or 28 days exhibited body weight decreases of 5.11%, 11.10%, 19.16%, and 24.18%, respectively, whereas the control group showed 9.17% gain in body weight. Total and free cyanide concentrations were detected in the liver, kidney, and heart of most of the rats in both the experimental and control groups, except for free cyanide in the control group that was not detected. Metabolism of the yellow cassava variety in experimental rats was capable of exposing the animals to cyanide, underscoring the need for its proper processing before consumption by humans.
Locally minimal topological groups
enhofer, Lydia Au\\ss; Dikranjan, Dikran; Domínguez, Xabier
2009-01-01
A Hausdorff topological group $(G,\\tau)$ is called locally minimal if there exists a neighborhood $U$ of 0 in $\\tau$ such that $U$ fails to be a neighborhood of zero in any Hausdorff group topology on $G$ which is strictly coarser than $\\tau.$ Examples of locally minimal groups are all subgroups of Banach-Lie groups, all locally compact groups and all minimal groups. Motivated by the fact that locally compact NSS groups are Lie groups, we study the connection between local minimality and the NSS property, establishing that under certain conditions, locally minimal NSS groups are metrizable. A symmetric subset of an abelian group containing zero is said to be a GTG set if it generates a group topology in an analogous way as convex and symmetric subsets are unit balls for pseudonorms on a vector space. We consider topological groups which have a neighborhood basis at zero consisting of GTG sets. Examples of these locally GTG groups are: locally pseudo--convex spaces, groups uniformly free from small subgroups (...
Ribes, Luis
2017-01-01
This book offers a detailed introduction to graph theoretic methods in profinite groups and applications to abstract groups. It is the first to provide a comprehensive treatment of the subject. The author begins by carefully developing relevant notions in topology, profinite groups and homology, including free products of profinite groups, cohomological methods in profinite groups, and fixed points of automorphisms of free pro-p groups. The final part of the book is dedicated to applications of the profinite theory to abstract groups, with sections on finitely generated subgroups of free groups, separability conditions in free and amalgamated products, and algorithms in free groups and finite monoids. Profinite Graphs and Groups will appeal to students and researchers interested in profinite groups, geometric group theory, graphs and connections with the theory of formal languages. A complete reference on the subject, the book includes historical and bibliographical notes as well as a discussion of open quest...
Diversity of Xiphinema americanum-group Species and Hierarchical Cluster Analysis of Morphometrics.
Lamberti, F; Ciancio, A
1993-09-01
Of the 39 species composing the Xiphinema americanum group, 14 were described originally from North America and two others have been reported from this region. Many species are very similar morphologically and can be distinguished only by a difficult comparison of various combinations of some morphometric characters. Study of morphometrics of 49 populations, including the type populations of the 39 species attributed to this group, by principal component analysis and hierarchical cluster analysis placed the populations into five subgroups, proposed here as the X. brevicolle subgroup (seven species), the X. americanum subgroup (17 species), the X. taylori subgroup (two species), the X. pachtaicum subgroup (eight species), and the X. lambertii subgroup (five species).
Diogo Verissimo
2017-01-01
Full Text Available In June 2016, we observed a group of Yellow-billed Oxpeckers foraging on a single male Giraffe, in the Savuti area of Chobe National Park, Botswana. From photographic evidence we estimate the Oxpecker group numbered between 51 and 60, the highest number on record for a single host.
Pearson, Matthew R; Lawless, Adrienne K; Brown, David B; Bravo, Adrian J
2015-04-01
In non-meditating samples, distinct facets of mindfulness are found to be negatively correlated, preventing the meaningful creation of a total mindfulness score. The present study used person-centered analyses to distinguish subgroups of college students based on their mindfulness scores, which allows the examination of individuals who are high (or low) on all facets of mindfulness. Using the Lo-Mendell-Rubin Adjusted LRT test, we settled on a 4-class solution that included a high mindfulness group (high on all 5 facets, N = 245), low mindfulness group (moderately low on all 5 facets, N = 563), judgmentally observing group (high on observing, but low on non-judging and acting with awareness, N =63), and non-judgmentally aware group (low on observing, but high on non-judging and acting with awareness, N =70). Consistent across all emotional outcomes including depressive symptoms, anxiety symptoms (i.e., worry), affective instability, and distress intolerance, we found that the judgmentally observing group had the most maladaptive emotional outcomes followed by the low mindfulness group. Both the high mindfulness group and the non-judgmentally aware group had the most adaptive emotional outcomes. We discuss the implications of person-centered analyses to exploring mindfulness as it relates to important psychological health outcomes.
Mohammad Mehdi Nasrabadi; Ali Gholamian
2014-11-01
Let be a group and $A = \\text{Aut}(G)$ be the group of automorphisms of . Then, the element $[g, ] = g^{-1}(g)$ is an autocommutator of $g \\in G$ and $ \\in A$. Hence, for any natural number the -th autocommutator subgroup of is defined as $K_{m}(G)=\\langle [g,_{1},\\ldots,_{m}]|g\\in G,_{1},\\ldots,_{m}\\in A\\rangle$, where $[g, _{1}, _{2},\\ldots, _{m}] = [[g,_{1},\\ldots,_{m−1}], _{m}]$. In this paper, we introduce the new notion of -nilpotent groups and classify all abelian groups which are -nilpotent groups.
Hillman Ken
2009-12-01
Full Text Available Abstract Background To compare two approaches to the statistical analysis of the relationship between the baseline incidence of adverse events and the effect of medical emergency teams (METs. Methods Using data from a cluster randomized controlled trial (the MERIT study, we analysed the relationship between the baseline incidence of adverse events and its change from baseline to the MET activation phase using quadratic modelling techniques. We compared the findings with those obtained with conventional subgroup analysis. Results Using linear and quadratic modelling techniques, we found that each unit increase in the baseline incidence of adverse events in MET hospitals was associated with a 0.59 unit subsequent reduction in adverse events (95%CI: 0.33 to 0.86 after MET implementation and activation. This applied to cardiac arrests (0.74; 95%CI: 0.52 to 0.95, unplanned ICU admissions (0.56; 95%CI: 0.26 to 0.85 and unexpected deaths (0.68; 95%CI: 0.45 to 0.90. Control hospitals showed a similar reduction only for cardiac arrests (0.95; 95%CI: 0.56 to 1.32. Comparison using conventional subgroup analysis, on the other hand, detected no significant difference between MET and control hospitals. Conclusions Our study showed that, in the MERIT study, when there was dependence of treatment effect on baseline performance, an approach based on regression modelling helped illustrate the nature and magnitude of such dependence while sub-group analysis did not. The ability to assess the nature and magnitude of such dependence may have policy implications. Regression technique may thus prove useful in analysing data when there is a conditional treatment effect.
Posttraumatic stress disorder post Iraq and Afghanistan: prevalence among military subgroups.
Hines, Lindsey A; Sundin, Josefin; Rona, Roberto J; Wessely, Simon; Fear, Nicola T
2014-09-01
A large body of research has been produced in recent years investigating posttraumatic stress disorder (PTSD) among military personnel following deployment to Iraq and Afghanistan, resulting in apparent differences in PTSD prevalence. We compare prevalence estimates for current PTSD between military subgroups, providing insight into how groups may be differentially affected by deployment. Systematic literature searches using the terms PTSD, stress disorder, and acute stress, combined with terms relating to military personnel, identified 49 relevant papers. Studies with a sample size of less than 100 and studies based on data for treatment seeking or injured populations were excluded. Studies were categorized according to theatre of deployment (Iraq or Afghanistan), combat and noncombat deployed samples, sex, enlistment type (regular or reserve and [or] National Guard), and service branch (for example, army, navy, and air force). Meta-analysis was used to assess PTSD prevalence across subgroups. There was large variability in PTSD prevalence between studies, but, regardless of heterogeneity, prevalence rates of PTSD were higher among studies of Iraq-deployed personnel (12.9%; 95% CI 11.3% to 14.4%), compared with personnel deployed to Afghanistan (7.1%; 95% CI 4.6% to 9.6%), combat deployed personnel, and personnel serving in the Canadian, US, or UK army or the navy or marines (12.4%; 95% CI 10.9% to 13.4%), compared with the other services (4.9%; 95% CI 1.4% to 8.4%). Contrary to findings from within-study comparisons, we did not find a difference in PTSD prevalence for regular active-duty and reserve or National Guard personnel. Categorizing studies according to deployment location and branch of service identified differences among subgroups that provide further support for factors underlying the development of PTSD.
Jensen Irene
2011-04-01
Full Text Available Abstract Background The overall objective was to evaluate the predictive validity of a subgroup classification based on the Swedish version of the MPI, the MPI-S, among gainfully employed workers with neck pain (NP and/or low back pain (LBP during a follow-up period of 18 and 36 months. Methods This is a prospective cohort study that is part of a larger longitudinal multi-centre study entitled Work and Health in the Process and Engineering Industries (AHA. The attempt was to classify individuals at risk for developing chronic disabling NP and LBP. This is the first study using the MPI-questionnaire in a working population with NP and LBP. Results Dysfunctional individuals (DYS demonstrated more statistically significant sickness absence compared to adaptive copers (AC after 36 months. DYS also had a threefold increase in the risk ratio of long-term sickness absence at 18 months. Interpersonally distressed (ID subgroup showed overall more sickness absence compared to the AC subgroup at the 36-month follow-up and had a twofold increase in the risk ratio of long-term sickness absence at 18 months. There was a significant difference in bodily pain, mental and physical health for ID and DYS subgroups compared to the AC group at both follow-ups. Conclusions The present study shows that this multidimensional approach to the classification of individuals based on psychological and psychosocial characteristics can distinguish different groups in gainfully employed working population with NP/LBP. The results in this study confirm the predictive validity of the MPI-S subgroup classification system.