WorldWideScience

Sample records for wu zhi kai

  1. Different Influences on Tacrolimus Pharmacokinetics by Coadministrations of Zhi Ke and Zhi Shi in Rats

    Science.gov (United States)

    Lin, Shiuan-Pey; Wu, Ping-Ping; Hou, Yu-Chi; Tsai, Shang-Yuan; Wang, Meng-Ju; Fang, Shih-Hua; Chao, Pei-Dawn Lee

    2011-01-01

    Tacrolimus, an immunosuppressant with narrow therapeutic window, has been used widely in transplant patients. Grapefruit juice and pomelo have been reported to increase the blood levels of tacrolimus. Zhi Ke and Zhi Shi, the ripe peels and unripe fruits of Citrus aurantium which is chemotaxonomically related to grapefruit and pomelo, are in wide use in clinical Chinese medicine. To investigate the possible interaction of these two Citrus herbs with tacrolimus, male Sprague-Dawley rats were orally given tacrolimus (1.5 mg/kg) with and without Zhi Ke and Zhi Shi decoctions in a cross-over design. Blood samples were withdrawn via cardiopuncture at specific time and quantitated by a microparticle enzyme immunoassay. In addition, to explore the mechanism of interaction, LS 180 cell line was used for the transport study of rhodamine 123, a typical substrate of P-glycoprotein (P-gp). The results showed that Zhi Shi significantly decreased the C max and AUC0−t of tacrolimus by 72.4% and 72.0%, respectively, whereas Zhi Ke did not affect tacrolimus pharmacokinetics. LS 180 cell line study indicated that Zhi Shi increased the efflux activity of P-gp, enabling us to explain the decreased oral bioavailability of tacrolimus caused by Zhi Shi. Hence, we suggest that Zhi Shi be contraindicated for transplant patients treated with tacrolimus to reduce the risk of allograft rejection. PMID:21318106

  2. Different Influences on Tacrolimus Pharmacokinetics by Coadministrations of Zhi Ke and Zhi Shi in Rats

    Directory of Open Access Journals (Sweden)

    Shiuan-Pey Lin

    2011-01-01

    Full Text Available Tacrolimus, an immunosuppressant with narrow therapeutic window, has been used widely in transplant patients. Grapefruit juice and pomelo have been reported to increase the blood levels of tacrolimus. Zhi Ke and Zhi Shi, the ripe peels and unripe fruits of Citrus aurantium which is chemotaxonomically related to grapefruit and pomelo, are in wide use in clinical Chinese medicine. To investigate the possible interaction of these two Citrus herbs with tacrolimus, male Sprague-Dawley rats were orally given tacrolimus (1.5 mg/kg with and without Zhi Ke and Zhi Shi decoctions in a cross-over design. Blood samples were withdrawn via cardiopuncture at specific time and quantitated by a microparticle enzyme immunoassay. In addition, to explore the mechanism of interaction, LS 180 cell line was used for the transport study of rhodamine 123, a typical substrate of P-glycoprotein (P-gp. The results showed that Zhi Shi significantly decreased the Cmax⁡ and AUC0-t of tacrolimus by 72.4% and 72.0%, respectively, whereas Zhi Ke did not affect tacrolimus pharmacokinetics. LS 180 cell line study indicated that Zhi Shi increased the efflux activity of P-gp, enabling us to explain the decreased oral bioavailability of tacrolimus caused by Zhi Shi. Hence, we suggest that Zhi Shi be contraindicated for transplant patients treated with tacrolimus to reduce the risk of allograft rejection.

  3. Loop-Loop Interactions Regulate KaiA-Stimulated KaiC Phosphorylation in the Cyanobacterial KaiABC Circadian Clock

    Energy Technology Data Exchange (ETDEWEB)

    Egli, Martin [Vanderbilt Univ., Nashville, TN (United States); Pattanayek, Rekha [Vanderbilt Univ., Nashville, TN (United States); Sheehan, Jonathan H. [Vanderbilt Univ., Nashville, TN (United States); Xu, Yao [Vanderbilt Univ., Nashville, TN (United States); Mori, Tetsuya [Vanderbilt Univ., Nashville, TN (United States); Smith, Jarrod A. [Vanderbilt Univ., Nashville, TN (United States); Johnson, Carl H. [Vanderbilt Univ., Nashville, TN (United States)

    2013-01-25

    We found that the Synechococcus elongatus KaiA, KaiB, and KaiC proteins in the presence of ATP generate a post-translational oscillator that runs in a temperature-compensated manner with a period of 24 h. KaiA dimer stimulates phosphorylation of KaiC hexamer at two sites per subunit, T432 and S431, and KaiB dimers antagonize KaiA action and induce KaiC subunit exchange. Neither the mechanism of KaiA-stimulated KaiC phosphorylation nor that of KaiB-mediated KaiC dephosphorylation is understood in detail at present. We demonstrate here that the A422V KaiC mutant sheds light on the former mechanism. It was previously reported that A422V is less sensitive to dark pulse-induced phase resetting and has a reduced amplitude of the KaiC phosphorylation rhythm in vivo. A422 maps to a loop (422-loop) that continues toward the phosphorylation sites. By pulling on the C-terminal peptide of KaiC (A-loop), KaiA removes restraints from the adjacent 422-loop whose increased flexibility indirectly promotes kinase activity. We found in the crystal structure that A422V KaiC lacks phosphorylation at S431 and exhibits a subtle, local conformational change relative to wild-type KaiC. Molecular dynamics simulations indicate higher mobility of the 422-loop in the absence of the A-loop and mobility differences in other areas associated with phosphorylation activity between wild-type and mutant KaiCs. Finally, the A-loop–422-loop relay that informs KaiC phosphorylation sites of KaiA dimer binding propagates to loops from neighboring KaiC subunits, thus providing support for a concerted allosteric mechanism of phosphorylation.

  4. CryoEM and Molecular Dynamics of the Circadian KaiB-KaiC Complex Indicates That KaiB Monomers Interact with KaiC and Block ATP Binding Clefts

    Energy Technology Data Exchange (ETDEWEB)

    Villarreal, Seth A.; Pattanayek, Rekha; Williams, Dewight R.; Mori, Tetsuya; Qin, Ximing; Johnson, Carl H.; Egli, Martin; Stewart, Phoebe L. [Case Western; (Vanderbilt); (Vanderbilt-MED)

    2014-10-02

    The circadian control of cellular processes in cyanobacteria is regulated by a posttranslational oscillator formed by three Kai proteins. During the oscillator cycle, KaiA serves to promote autophosphorylation of KaiC while KaiB counteracts this effect. Here, we present a crystallographic structure of the wild-type Synechococcus elongatus KaiB and a cryo-electron microscopy (cryoEM) structure of a KaiBC complex. The crystal structure shows the expected dimer core structure and significant conformational variations of the KaiB C-terminal region, which is functionally important in maintaining rhythmicity. The KaiBC sample was formed with a C-terminally truncated form of KaiC, KaiC-Δ489, which is persistently phosphorylated. The KaiB–KaiC-Δ489 structure reveals that the KaiC hexamer can bind six monomers of KaiB, which form a continuous ring of density in the KaiBC complex. We performed cryoEM-guided molecular dynamics flexible fitting simulations with crystal structures of KaiB and KaiC to probe the KaiBC protein–protein interface. This analysis indicated a favorable binding mode for the KaiB monomer on the CII end of KaiC, involving two adjacent KaiC subunits and spanning an ATP binding cleft. A KaiC mutation, R468C, which has been shown to affect the affinity of KaiB for KaiC and lengthen the period in a bioluminescence rhythm assay, is found within the middle of the predicted KaiBC interface. The proposed KaiB binding mode blocks access to the ATP binding cleft in the CII ring of KaiC, which provides insight into how KaiB might influence the phosphorylation status of KaiC.

  5. Kai õpetab iseennast / Kai Kaljo ; intervjueerinud R[eet] V[arblane

    Index Scriptorium Estoniae

    Kaljo, Kai, 1959-

    2011-01-01

    Kai Kaljo isikunäitus "Kai õpetab iseennast" Hobusepea galeriis 2.-14. novembrini 2011. Kaks videot seostuvad Kai Kaljo õppejõutööga Tallinna Ülikoolis, ka kaasaegse kunsti professori ametist Tallinna Ülikooli kunstihariduse osakonnas. Näitusel osale külalisesinejana Austraalia kirjanik Luke Davies, näitusel oli tema lühifilm "Õhk"

  6. Survey of Two New (Kai 1 and Kai 2) and Other Blood Groups in Dogs of North America.

    Science.gov (United States)

    Euler, C C; Lee, J H; Kim, H Y; Raj, K; Mizukami, K; Giger, U

    2016-09-01

    Based upon serology, >10 canine blood group systems have been reported. We surveyed dogs for dog erythrocyte antigen (DEA) 1 and 2 new blood types (Kai 1 and Kai 2), and some samples also were screened for Dal and DEA 3, 4, and 7. Blood samples provided by owners, breeders, animal blood banks, and clinical laboratories were typed for DEA 1 by an immunochromatographic strip technique with a monoclonal antibody and analysis of band intensity. Both new antigens, the Dal and other DEAs (except DEA 7 by tube method), were assessed by a gel column method with either monoclonal or polyclonal antibodies. The same gel column method was applied for alloantibody detection. Of 503 dogs typed, 59.6% were DEA 1+ with 4% weakly, 10% moderately, and 45.6% strongly DEA 1+. Regarding Kai 1 and Kai 2, 94% were Kai 1+/Kai 2-, 5% were Kai 1-/Kai 2- and 1% were Kai 1-/Kai 2+, but none were Kai 1+/Kai 2+. There was no relationship between Kai 1/Kai 2 and other blood types tested. Plasma from DEA 1-, Kai 1-, Kai 2- dogs, or some combination of these contained no detectable alloantibodies against DEA 1 and Kai 1 or Kai, respectively. The new blood types, called Kai 1 and Kai 2, are unrelated to DEA 1, 3, 4, and 7 and Dal. Kai 1+/Kai 2- dogs were most commonly found in North America. The clinical relevance of Kai 1 and Kai 2 in canine transfusion medicine still needs to be elucidated. Copyright © 2016 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

  7. Anti-RhoC siRNAs inhibit the proliferation and invasiveness of breast cancer cells via modulating the KAI1, MMP9, and CXCR4 expression

    OpenAIRE

    Xu, Xu-Dong; Shen, Han-Bin; Zhu, Li; Lu, Jian-Qin; Zhang, Lin; Luo, Zhi-Yong; Wu, Ya-Qun

    2017-01-01

    Xu-Dong Xu,1 Han-Bin Shen,1 Li Zhu,2 Jian-Qin Lu,2 Lin Zhang,3 Zhi-Yong Luo,3 Ya-Qun Wu3 1Department of Thyroid and Breast Surgery, The Fifth Hospital of Wuhan, Hanyang District, 2Department of Oncology, 3Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China Abstract: Overexpression of RhoC in breast cancer cells indicates poor prognosis. In the present study, we ai...

  8. Anti-RhoC siRNAs inhibit the proliferation and invasiveness of breast cancer cells via modulating the KAI1, MMP9, and CXCR4 expression

    Directory of Open Access Journals (Sweden)

    Xu X

    2017-03-01

    Full Text Available Xu-Dong Xu,1 Han-Bin Shen,1 Li Zhu,2 Jian-Qin Lu,2 Lin Zhang,3 Zhi-Yong Luo,3 Ya-Qun Wu3 1Department of Thyroid and Breast Surgery, The Fifth Hospital of Wuhan, Hanyang District, 2Department of Oncology, 3Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China Abstract: Overexpression of RhoC in breast cancer cells indicates poor prognosis. In the present study, we aim to investigate the possible antitumor effects of anti-RhoC small-interfering RNA (siRNA in inflammatory breast cancer cells. In this study, a specific anti-RhoC siRNA was used to inhibit RhoC synthesis. Transfection of anti-RhoC siRNA into two IBC cells SUM149 and SUM190 induced extensive degradation of target mRNA and led to significant decrease in the synthesis of protein. Anti-RhoC siRNA inhibited cell proliferation and invasion, increased cell apoptosis, and induced cell cycle arrest in vitro. Moreover, the transfection of siRNA increased the expression of KAI1 and decreased the expression of MMP9 and CXCR4 in both mRNA and protein levels. Furthermore, transplantation tumor experiments in BALB/c-nu mice showed that intratumoral injection of anti-RhoC siRNA inhibited tumor growth and increased survival rate. Our results suggested that RhoC gene silencing with specific anti-RhoC siRNA would be a potential therapeutic method for metastatic breast cancer. Keywords: gene silencing, proliferation, apoptosis, cell cycle arrest

  9. On Li Zhi's Theory of Growing up in Spirit

    Institute of Scientific and Technical Information of China (English)

    Wang Junjiang

    2006-01-01

    The theory of growing up in spirit is the core of Li Zhi's thought.The theory attempts to get rid of the limit of the rigid ethical doctrine of Confucianismand to encourage growth in a helpful person for the benefit of the country,which demands both a free environment of society and enough courage and insight of the individual.At the same time,the criterion of growing up in spirit indicates the limitation of Li Zhi's thought.His free exploration,however,provides various revelations for us.

  10. The KAI Cognitive Style Inventory: Was it personality all along?

    OpenAIRE

    Von Wittich, D.; Antonakis, J.

    2011-01-01

    Kirton's Adaption-Innovation Inventory (KAI) is a widely-used measure of "cognitive style." Surprisingly, there is very little research investigating the discriminant and incremental validity of the KAI. In two studies (n = 213), we examined whether (a) we could predict KAI scores with the "big five" personality dimensions and (b) the KAI scores predicted leadership behavior when controlling for personality and ability. Correcting for measurement error, we found that KAI scores were predicted...

  11. Dephosphorylation of the Core Clock Protein KaiC in the Cyanobacterial KaiABC Circadian Oscillator Proceeds via an ATP Synthase Mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Egli, Martin; Mori, Tetsuya; Pattanayek, Rekha; Xu, Yao; Qin, Ximing; Johnson, Carl H. (Vanderbilt)

    2014-10-02

    The circadian clock of the cyanobacterium Synechococcus elongatus can be reconstituted in vitro from three proteins, KaiA, KaiB, and KaiC in the presence of ATP, to tick in a temperature-compensated manner. KaiC, the central cog of this oscillator, forms a homohexamer with 12 ATP molecules bound between its N- and C-terminal domains and exhibits unusual properties. Both the N-terminal (CI) and C-terminal (CII) domains harbor ATPase activity, and the subunit interfaces between CII domains are the sites of autokinase and autophosphatase activities. Hydrolysis of ATP correlates with phosphorylation at threonine and serine sites across subunits in an orchestrated manner, such that first T432 and then S431 are phosphorylated, followed by dephosphorylation of these residues in the same order. Although structural work has provided insight into the mechanisms of ATPase and kinase, the location and mechanism of the phosphatase have remained enigmatic. From the available experimental data based on a range of approaches, including KaiC crystal structures and small-angle X-ray scattering models, metal ion dependence, site-directed mutagenesis (i.e., E318, the general base), and measurements of the associated clock periods, phosphorylation patterns, and dephosphorylation courses as well as a lack of sequence motifs in KaiC that are typically associated with known phosphatases, we hypothesized that KaiCII makes use of the same active site for phosphorylation and dephosphorlyation. We observed that wild-type KaiC (wt-KaiC) exhibits an ATP synthase activity that is significantly reduced in the T432A/S431A mutant. We interpret the first observation as evidence that KaiCII is a phosphotransferase instead of a phosphatase and the second that the enzyme is capable of generating ATP, both from ADP and P{sub i} (in a reversal of the ATPase reaction) and from ADP and P-T432/P-S431 (dephosphorylation). This new concept regarding the mechanism of dephosphorylation is also supported by the

  12. ADP Regulates the Structure and Function of the Protein KaiC

    Science.gov (United States)

    2016-08-11

    LiWang lab exploited this in vitro clock system to gain an atomic -resolution understanding of a circadian clock. The rationale is that fundamental...researchers are Hispanic. On a peer-reviewed research article from the LiWang lab, a Hispanic undergraduate student was an author, as were two non...Using both NMR and fluorescence spectroscopy , the LiWang lab showed that KaiA enhances KaiB-KaiC binding, and KaiC enhances KaiA-KaiB binding (Tseng et

  13. Circadian clock protein KaiC forms ATP-dependent hexameric rings and binds DNA.

    Science.gov (United States)

    Mori, Tetsuya; Saveliev, Sergei V; Xu, Yao; Stafford, Walter F; Cox, Michael M; Inman, Ross B; Johnson, Carl H

    2002-12-24

    KaiC from Synechococcus elongatus PCC 7942 (KaiC) is an essential circadian clock protein in cyanobacteria. Previous sequence analyses suggested its inclusion in the RecADnaB superfamily. A characteristic of the proteins of this superfamily is that they form homohexameric complexes that bind DNA. We show here that KaiC also forms ring complexes with a central pore that can be visualized by electron microscopy. A combination of analytical ultracentrifugation and chromatographic analyses demonstrates that these complexes are hexameric. The association of KaiC molecules into hexamers depends on the presence of ATP. The KaiC sequence does not include the obvious DNA-binding motifs found in RecA or DnaB. Nevertheless, KaiC binds forked DNA substrates. These data support the inclusion of KaiC into the RecADnaB superfamily and have important implications for enzymatic activity of KaiC in the circadian clock mechanism that regulates global changes in gene expression patterns.

  14. The Legionella pneumophila kai operon is implicated in stress response and confers fitness in competitive environments

    Science.gov (United States)

    Loza-Correa, Maria; Sahr, Tobias; Rolando, Monica; Daniels, Craig; Petit, Pierre; Skarina, Tania; Valero, Laura Gomez; Dervins-Ravault, Delphine; Honoré, Nadine; Savchenko, Aleksey; Buchrieser, Carmen

    2014-01-01

    Summary Legionella pneumophila uses aquatic protozoa as replication niche and protection from harsh environments. Although L. pneumophila is not known to have a circadian clock, it encodes homologues of the KaiBC proteins of Cyanobacteria that regulate circadian gene expression. We show that L. pneumophila kaiB, kaiC and the downstream gene lpp1114, are transcribed as a unit under the control of the stress sigma factor RpoS. KaiC and KaiB of L. pneumophila do not interact as evidenced by yeast and bacterial two-hybrid analyses. Fusion of the C-terminal residues of cyanobacterial KaiB to Legionella KaiB restores their interaction. In contrast, KaiC of L. pneumophila conserved autophosphorylation activity, but KaiB does not trigger the dephosphorylation of KaiC like in Cyanobacteria. The crystal structure of L. pneumophila KaiB suggests that it is an oxidoreductase-like protein with a typical thioredoxin fold. Indeed, mutant analyses revealed that the kai operon-encoded proteins increase fitness of L. pneumophila in competitive environments, and confer higher resistance to oxidative and sodium stress. The phylogenetic analysis indicates that L. pneumophila KaiBC resemble Synechosystis KaiC2B2 and not circadian KaiB1C1. Thus, the L. pneumophila Kai proteins do not encode a circadian clock, but enhance stress resistance and adaption to changes in the environments. PMID:23957615

  15. Lightcurve and Rotation Period Determinations for 1599 Giomus and 1888 Zu Chong-Zhi

    Science.gov (United States)

    Foylan, Mike; Rowe, Basil; Smith, Kevin Stephen

    2018-04-01

    Collaborative CCD photometric observations of mainbelt asteroids 1599 Giomus (1950 WA) and 1888 Zu Chong-Zhi (1964 VO1) were acquired during 2017 November and December. A rotation period of 9.53 ± 0.03 h and amplitude of A = 0.06 ± 0.05 mag were determined for 1599 Giomus and 11.053 ± 0.003 h and amplitude of A = 0.56 ± 0.05 mag were determined for 1888 Zu Chong-Zhi.

  16. Kai Kaljo: "Aeg-ajalt tuleb ennast peeglist vaadata" / Kai Kaljo ; intervjueerinud Reet Varblane

    Index Scriptorium Estoniae

    Kaljo, Kai, 1959-

    2009-01-01

    Videokunstnik Kai Kaljo oma isikunäitusest "Ainult eestlastele" Tallinna Kunstihoone galeriis, maalikunstisti tähendusest talle, kunstiteostest, mis on teda mõjutanud, Tallinnasse püstitatud Vabadussõja võidusambast

  17. [Data mining analysis of professor Li Fa-zhi AIDS itchy skin medical record].

    Science.gov (United States)

    Wang, Dan-Ni; Li, Zhen; Xu, Li-Ran; Guo, Hui-Jun

    2013-08-01

    Analysis of professor Li Fa-zhi in the treatment of AIDS drug laws of itchy skin, provide the corresponding drug reference basis for Chinese medicine treatment of AIDS, skin itching. By using the method of analyzing the complex network of Weishi county, Henan in 2007 October to 2011 July during an interview with professor Li Fa-zhi treatment of AIDS patients with skin pruritus, etiology and pathogenesis analysis, skin itching AIDS syndrome differentiation of old Chinese medicine treatment and medication rule. The use of multi-dimensional query analysis, core drug skin itching AIDS treatment in this study as a windbreak, cicada slough, bupleurum, Qufeng solution table drug, licorice detoxification efficacy of drugs, Radix Scutellariae, Kochia scoparia, clearing away heat and promoting diuresis medicine; core prescription for Jingfang San streak virus. Professor Li Fa-zhi treatment of AIDS in the skin itching Qufeng solution table dehumidification antipruritic treatment.

  18. Eesti disaini uudised / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2005-01-01

    Toivo Raidmetsa isiknäitus "Barokist dadani" Rotermanni soolalaos, tekstiilikunstnik Helena Palmi ehted. Disainitudeng Liina-Kai Raivet sai teise koha Itaalias keraamiliste plaatide konkursil "Marchitecture"

  19. DA Masolo A Review of Kai Kresse's Philosophising in Mombasa ...

    African Journals Online (AJOL)

    DA Masolo

    Kai Kresse's Philosophising in Mombasa: Knowledge, Islam and Intellectual Practice on the Swahili Coast 1. A Review of Kai ... (Edinburgh: Edinburgh University Press, 2007, for the. International African Institute, London, in collaboration with.

  20. Root growth of Cynodon dactylon and Eleusine indica collected from motorways at different concentrations of lead.

    Science.gov (United States)

    Wong, M H; Lau, W M

    1985-04-01

    An ecological survey was conducted on the roadside vegetation at three different sites: Tai Po, a commercial and residential area (average annual daily traffic (AADT) = 23730; and Shek O and Wu Kai Sha, recreational areas (AADT = 1590 and 20, respectively). Cynodon dactylon and Eleusine indica were the two most dominant species recorded. The Tai Po site had higher Pb contents in both soil and plant, followed by Shek O, and then Wu Kai Sha. Tillers of C. dactylon and E. indica from the three sites were subjected to a series concentrations of Pb(NO3)2. By comparing their indexes of tolerance and values of 14-day EC50 (effective concentration reducing the normal root growth by 50%), roadside populations of the two grasses collected from Tai Po and Shek O, especially the former one, were more tolerant to elevated levels of Pb compared with those collected from Wu Kai Sha.

  1. Intervjuu Kai Vöckleriga = Interview with Kai Vöckler / intervjueerinud Triin Ojaste

    Index Scriptorium Estoniae

    Vöckler, Kai

    2011-01-01

    Lääne-Saksamaal sündinud urbanist, urbanistikaga tegeleva organisatsiooni Archis Interventions'i üks asutaja Kai Vöckler endast, Archis Interventions'i tegevusest, Ida-Euroopast, Balkanist, uuest arhitektuurist ja linnaehitusest, uue vabaduse antud võimalustest ja selle mõiste mitmetähenduslikkusest

  2. Development of Ling-zhi industry in China – emanated from the artificial cultivation in the Institute of Microbiology, Chinese Academy of Sciences (IMCAS

    Directory of Open Access Journals (Sweden)

    Saifei Li

    2016-04-01

    Full Text Available Ling-zhi is a medicinal herb that generally refers to a fungus in the genus Ganoderma. It has been used as a medicinal mushroom in traditional Chinese medicine for more than 2000 years. Mycologists at the Institute of Microbiology, Chinese Academy of Sciences (IMCAS first artificially cultivated the Ling-zhi fruiting body in the late 1960s (X.J. Liu’s team. In IMCAS, different research teams have extensively studied Ling-zhi in the aspects of national resource surveys, systematic taxonomy, chemical analysis, and processing for medicinal and health applications. The research results from IMCAS have provided essential support and prompted the development of the Ling-zhi industry in China to some extent. This review aims to summarize the history of research on Ling-zhi in IMCAS and its role in the development of the Ling-zhi economy.

  3. Hea kultuuriantropoloog peab olema empaatiline / Kai Herkel ; intervjueerinud Reet Varblane

    Index Scriptorium Estoniae

    Herkel, Kai, 1963-

    2009-01-01

    Kai Herkeli Tiibeti-teemalisest näitusest "Himaalaja lapsed" Tallinna Linnagaleriis. Eksponeeritud fotod ja videod. Kai Herkel teeb Helsingi ülikooli sotsiaal- ja kultuuriantropoloogia erialal magistritööd lapsmunkade elust, oma kunstiprojektis on ta keskendunud Lamayuru kloostrikoolis õppivatele lapsmunkadele

  4. [Data mining analysis of professor Li Fa-zhi AIDS herpes zoster medical record].

    Science.gov (United States)

    Wang, Dan-Ni; Li, Zhen; Xu, Li-Ran; Guo, Hui-Jun

    2013-08-01

    Analysis of professor Li Fa-zhi in the treatment of AIDS drug laws of herpes zoster and postherpetic neuralgia, provide reference for the use of Chinese medicine treatment of AIDS, herpes zoster and postherpetic neuralgia. By using the method of analyzing the complex network of Weishi county, Henan in 2007 October to 2011 July during an interview with professor Li Fa-zhi treatment of AIDS of herpes zoster and postherpetic neuralgia patients, patients are input structured clinical information collection system, into the analysis of the data, carries on the research analysis theory of traditional Chinese medicine compatibility system algorithm and complex network analysis the use of complex networks. The use of multi-dimensional query analysis of AIDS drugs, the core of herpes zoster and postherpetic neuralgia treated in this study are Scutellariae Radix, Glucyrrhizae Radix, Carthame Flos, Plantaginis Semen, Trichosamthis Fructus, Angelicae Sinensis Radix, Gentianae Radix; core prescription for Longdan Xiegan decoction and Trichosanthes red liquorice decoction. Professor Li Fa-zhi treatment of AIDS, herpes zoster and postherpetic neuralgia by clearing heat and removing dampness and activating blood circulation to.

  5. Kai Kaljo video-workshopil Ljubljanas

    Index Scriptorium Estoniae

    2000-01-01

    Video-workshop "Crossing Over 4" 9.-23. XII 1999 Ljubljana meedialaboris. Korraldajad videokunsti professor Nina Czegledy Torontost ja bulgaaria kuraator Iliyana Nedkova. Eestit esindanud Kai Kaljo esitas videos "Pathetique" oma versiooni Beethoveni "Pateetilisest sonaadist"

  6. Cisplatin Induces Up-Regulation of KAI1, a Metastasis Suppressor ...

    African Journals Online (AJOL)

    Purpose: To investigate the effect of cisplatin on cell toxicity and metastasis through modulation of KAI1 gene expression. Methods: MCF-7cells were incubated with different concentrations of cisplatin for 24 h. RNA was extracted by trizol and cDNA synthesized. KAI1 and TBP were chosen as target and internal control ...

  7. The structure of the karrikin-insensitive protein (KAI2) in Arabidopsis thaliana.

    Science.gov (United States)

    Bythell-Douglas, Rohan; Waters, Mark T; Scaffidi, Adrian; Flematti, Gavin R; Smith, Steven M; Bond, Charles S

    2013-01-01

    KARRIKIN INSENSITIVE 2 (KAI2) is an α/β hydrolase involved in seed germination and seedling development. It is essential for plant responses to karrikins, a class of butenolide compounds derived from burnt plant material that are structurally similar to strigolactone plant hormones. The mechanistic basis for the function of KAI2 in plant development remains unclear. We have determined the crystal structure of Arabidopsis thaliana KAI2 in space groups P2(1) 2(1) 2(1) (a =63.57 Å, b =66.26 Å, c =78.25 Å) and P2(1) (a =50.20 Å, b =56.04 Å, c =52.43 Å, β =116.12°) to 1.55 and 2.11 Å respectively. The catalytic residues are positioned within a large hydrophobic pocket similar to that of DAD2, a protein required for strigolactone response in Petunia hybrida. KAI2 possesses a second solvent-accessible pocket, adjacent to the active site cavity, which offers the possibility of allosteric regulation. The structure of KAI2 is consistent with its designation as a serine hydrolase, as well as previous data implicating the protein in karrikin and strigolactone signalling.

  8. The structure of the karrikin-insensitive protein (KAI2 in Arabidopsis thaliana.

    Directory of Open Access Journals (Sweden)

    Rohan Bythell-Douglas

    Full Text Available KARRIKIN INSENSITIVE 2 (KAI2 is an α/β hydrolase involved in seed germination and seedling development. It is essential for plant responses to karrikins, a class of butenolide compounds derived from burnt plant material that are structurally similar to strigolactone plant hormones. The mechanistic basis for the function of KAI2 in plant development remains unclear. We have determined the crystal structure of Arabidopsis thaliana KAI2 in space groups P2(1 2(1 2(1 (a =63.57 Å, b =66.26 Å, c =78.25 Å and P2(1 (a =50.20 Å, b =56.04 Å, c =52.43 Å, β =116.12° to 1.55 and 2.11 Å respectively. The catalytic residues are positioned within a large hydrophobic pocket similar to that of DAD2, a protein required for strigolactone response in Petunia hybrida. KAI2 possesses a second solvent-accessible pocket, adjacent to the active site cavity, which offers the possibility of allosteric regulation. The structure of KAI2 is consistent with its designation as a serine hydrolase, as well as previous data implicating the protein in karrikin and strigolactone signalling.

  9. Co-expression of the C-terminal domain of Yersinia enterocolitica ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 1. Co-expression of the C-terminal domain of Yersinia enterocolitica invasin enhances the efficacy of classical swine-fever-vectored vaccine based on human adenovirus. Helin Li Pengbo Ning Zhi Lin Wulong Liang Kai Kang Lei He Yanming Zhang. Articles Volume ...

  10. Wu Chien-Shiung: A brief biography

    Science.gov (United States)

    Chiang, Tsai-Chien

    2015-12-01

    My first encounter with professor Wu Chien-Shiung, a leading experimental physicist, 31 years ago inspired me to write her biography. I received much encouragement when planning this biography, especially from Dr. Yang Chen Ning, whose biography I wrote later. The real challenges in writing Wu's biography were finding the balance between both sides of her life and overcoming the obstacle that, unlike theoretical physicists (such as Yang), experimental physicists are inclined more to deeds than to words.

  11. Kai Kaljo tunnustatus jätkub

    Index Scriptorium Estoniae

    2000-01-01

    Kai Kaljo esinemisest kuraator Hans Knolli näitusel "Communication...", New Yorgis Branka Stipancici kureeritud näitusel "Chinese whispers", Lõuna-Koreas Tom van Vliet kureeritud VI Pusani rahvusvahelisel kaasaegse kunsti festivalil, "World Wide Video" festivalil Amsterdamis

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Co-expression of the C-terminal domain of Yersinia enterocolitica invasin enhances the efficacy of classical swine-fever-vectored vaccine based on human adenovirus · Helin Li Pengbo Ning Zhi Lin Wulong Liang Kai Kang Lei He Yanming Zhang · More Details Abstract Fulltext PDF. The use of adenovirus vector-based ...

  13. Expression of KAI1/CD82 and MRP-1/CD9 in transitional cell carcinoma of bladder.

    Science.gov (United States)

    Ai, Xing; Zhang, Xu; Wu, Zhun; Ma, Xin; Ju, Zhenghua; Wang, Baojun; Shi, Taoping

    2007-02-01

    The expression of KAI1/CD82 and MRP-1/CD9 in transitional cell carcinoma of bladder (TCCB) and its clinical significance were investigated. Immunohistochemistry was used to detect KAI1/CD82 and MRP-1/CD9 protein expression in 52 TCCB specimens. Correlation between the expression of KAI1/CD82 and MRP-1/CD9 to clinicopathologic factors was statistically analyzed. The results showed that the positive rate of KAI1/CD82 and MRP-1/CD9 in TCCB was 50% and 61.5%, respectively. The MRP-1/CD9 and KAI1/CD82 expression was significantly associated with grade of TCCB (PMRP-1/CD9 or KAI1/CD82 expression and clinical stage of TCCB (P>0.05). The expression level of MRP-1/CD9 and KAI1/CD82 in recurrent TCCB samples was lower than that in non-recurrent samples (PMRP-1/CD9 expression was statistically significant (r=0.316, PMRP-1/CD9 expression may be important prognostic indicators and potentially useful for assessing the biological behavior of TCCB.

  14. Kais-Vesik said ebameeldiva vastase / Andres Kalvik

    Index Scriptorium Estoniae

    Kalvik, Andres, 1982-

    2007-01-01

    Stavangeris Suure Slämmi alagrupis kolmanda koha saanud ning koha 24 parema seas taganud Kristjan Kais ja Rivo Vesik lähevad play-off'i avaringis vastamisi Saksamaa duoga Mischa Urbatzka - Jonas Reckermann

  15. Peng et al., Afr J Tradit Complement Altern Med. (2015) 12(5):35-45 ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    as a kind of specific application of syndrome differentiation, You Gu Wu Yun, documented .... Zhi-Zhu-Wan (ZZW), a famous Chinese medical preparation used to treat functional dyspepsia, contains Aurantii fructus ..... Abdominal pain, vomiting,.

  16. KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer

    Directory of Open Access Journals (Sweden)

    Park Jung-Jin

    2012-03-01

    Full Text Available Abstract Background KAI1 was initially identified as a metastasis-suppressor gene in prostate cancer. It is a member of the tetraspan transmembrane superfamily (TM4SF of membrane glycoproteins. As part of a tetraspanin-enriched microdomain (TEM, KAI1 inhibits tumor metastasis by negative regulation of Src. However, the underlying regulatory mechanism has not yet been fully elucidated. CUB-domain-containing protein 1 (CDCP1, which was previously known as tetraspanin-interacting protein in TEM, promoted metastasis via enhancement of Src activity. To better understand how KAI1 is involved in the negative regulation of Src, we here examined the function of KAI1 in CDCP1-mediated Src kinase activation and the consequences of this process, focusing on HIF-1 α and VEGF expression. Methods We used the human prostate cancer cell line PC3 which was devoid of KAI1 expression. Vector-transfected cells (PC3-GFP clone #8 and KAI1-expressing PC3 clones (PC3-KAI1 clone #5 and #6 were picked after stable transfection with KAI1 cDNA and selection in 800 μg/ml G418. Protein levels were assessed by immunoblotting and VEGF reporter gene activity was measured by assaying luciferase activitiy. We followed tumor growth in vivo and immunohistochemistry was performed for detection of HIF-1, CDCP1, and VHL protein level. Results We demonstrated that Hypoxia-inducible factor 1α (HIF-1α and VEGF expression were significantly inhibited by restoration of KAI1 in PC3 cells. In response to KAI1 expression, CDCP1-enhanced Src activation was down-regulated and the level of von Hippel-Lindau (VHL protein was significantly increased. In an in vivo xenograft model, KAI1 inhibited the expression of CDCP1 and HIF-1α. Conclusions These novel observations may indicate that KAI1 exerts profound metastasis-suppressor activity in the tumor malignancy process via inhibition of CDCP1-mediated Src activation, followed by VHL-induced HIF-1α degradation and, ultimately, decreased VEGF

  17. County town -- jian-zhi town differentials and migration to towns in China.

    Science.gov (United States)

    Ma, R

    1993-07-01

    China's urbanization process is unique in having been due to economic systems and migration policies. Towns and townships in rural areas are different from cities in their social and economic characteristics and their structure and function. The urban system in China is initially described with the distinction drawn between cities, "jian-zhi towns", (organic town) which are officially recognized, and rural areas. Analysis is provided f the economic and residential registration status of town residents and migration in northern China. Data were obtained from a 1987 survey of 1314 households in Wongnioute Banner in Inner Mongolia, and a 1985 migration survey of 2089 rural households in 41 villages. The study area was selected because jian-zhi town status was easily obtained and the are needed more towns for local administration and trade; the area was similar in geographic, social, economic, and cultural characteristics to other northern and northwestern regions. The Wongnioute Banner comprises 5 towns (Qiaotou, Wufendi, Hairesu, Wuduentaohai, and Wutonghua) and 1 country town (Wudan). All citizens from birth have an agricultural or nonagricultural status, which can be changed by passing national exams or completing a university education, joining the military and becoming an officer, marrying someone with a nonagricultural status, reunifying the family, or holding a special program. Quotas are set annually for status changes, e.g. in Tibet Autonomous Region the annual quota was 3%. Town residents may have either status. In the sample, 56.6% lived in town and had a nonagricultural status; 17.7% of heads of household town residents had an agricultural status and had stronger ties to villages because of family connections. Commuters are a third group and comprise 8.9%. County towns and jian-zhi towns are grouped the same, but are quite different in population size. Wudan had a population of 27,600 spread over an area of 480 hectares. The jian-zhi towns each had an

  18. Pühendumusuuringute tegemine pole levinud / Kai Vare

    Index Scriptorium Estoniae

    Vare, Kai, 1968-

    2004-01-01

    Reval Hotelligrupp AS-is ja Saku Õlletehases läbi viidud töötajate rahulolu-uuringutest. Kommenteerivad Mari-Liis Eensalu, Kai Prinits ja Tiiu Vilms. Vt. samas: Narva Elektrivõrkudes töötavad Euroopa pühendunuimad inimesed

  19. Tumor suppressor KAI1 affects integrin αvβ3-mediated ovarian cancer cell adhesion, motility, and proliferation

    International Nuclear Information System (INIS)

    Ruseva, Zlatna; Geiger, Pamina Xenia Charlotte; Hutzler, Peter; Kotzsch, Matthias; Luber, Birgit; Schmitt, Manfred; Gross, Eva; Reuning, Ute

    2009-01-01

    The tetraspanin KAI1 had been described as a metastasis suppressor in many different cancer types, a function for which associations of KAI1 with adhesion and signaling receptors of the integrin superfamily likely play a role. In ovarian cancer, integrin αvβ3 correlates with tumor progression and its elevation in vitro provoked enhanced cell adhesion accompanied by significant increases in cell motility and proliferation in the presence of its major ligand vitronectin. In the present study, we characterized integrin αvβ3-mediated tumor biological effects as a function of cellular KAI1 restoration and proved for the first time that KAI1, besides its already known physical crosstalk with β1-integrins, also colocalizes with integrin αvβ3. Functionally, elevated KAI1 levels drastically increased integrin αvβ3/vitronectin-dependent ovarian cancer cell adhesion. Since an intermediate level of cell adhesive strength is required for optimal cell migration, we next studied ovarian cancer cell motility as a function of KAI1 restoration. By time lapse video microscopy, we found impaired integrin αvβ3/vitronectin-mediated cell migration most probably due to strongly enhanced cellular immobilization onto the adhesion-supporting matrix. Moreover, KAI1 reexpression significantly diminished cell proliferation. These data strongly indicate that KAI1 may suppress ovarian cancer progression by inhibiting integrin αvβ3/vitronectin-provoked tumor cell motility and proliferation as important hallmarks of the oncogenic process.

  20. Overexpression of KAI1 induces autophagy and increases MiaPaCa-2 cell survival through the phosphorylation of extracellular signal-regulated kinases

    International Nuclear Information System (INIS)

    Wu, Chun-Yan; Yan, Jun; Yang, Yue-Feng; Xiao, Feng-Jun; Li, Qing-Fang; Zhang, Qun-Wei; Wang, Li-Sheng; Guo, Xiao-Zhong; Wang, Hua

    2011-01-01

    Research highlights: → We first investigate the effects of KAI1 on autophagy in MiaPaCa-2 cells. → Our findings demonstrate that KAI1 induces autophagy, which in turn inhibits KAI1-induced apoptosis. → This study also supplies a possible novel therapeutic method for the treatment of pancreatic cancer using autophagy inhibitors. -- Abstract: KAI1, a metastasis-suppressor gene belonging to the tetraspanin family, is known to inhibit cancer metastasis without affecting the primary tumorigenicity by inhibiting the epidermal growth factor (EGF) signaling pathway. Recent studies have shown that hypoxic conditions of solid tumors induce high-level autophagy and KAI1 expression. However, the relationship between autophagy and KAI1 remains unclear. By using transmission electron microscopy, confocal microscopy, and Western blotting, we found that KAI1 can induce autophagy in a dose- and time-dependent manner in the human pancreatic cell line MiaPaCa-2. KAI1-induced autophagy was confirmed by the expression of autophagy-related proteins LC3 and Beclin 1. KAI1 induces autophagy through phosphorylation of extracellular signal-related kinases rather than that of AKT. KAI1-induced autophagy protects MiaPaCa-2 cells from apoptosis and proliferation inhibition partially through the downregulation of poly [adenosine diphosphate (ADP)-ribose] polymerase (PARP) cleavage and caspase-3 activation.

  1. Chien-Shiung Wu: An Icon of Physicist and Woman Scientist in China

    Science.gov (United States)

    Zhu, Yuelin

    2014-03-01

    Chien-Shiung Wu, the first female president of APS, is a well-known figure in China, a figure who serves as an inspiration for youths, especially young women, to study science and particularly physics. In this presentation, a historical perspective will be used to show how such an icon was formed. Born in 1912, the year of the Republic Revolution, Wu was in the first generation of physicists in China and her college mentor was a student of Marie Curie. When Wu came to the U.S. for graduate studies in the 1930s, it was a ``golden age'' for nuclear physics, and the invention of the cyclotron by E. O. Lawrence put UC Berkeley at the frontier. Wu was trained there, with Lawrence as her advisor, and later became an expert in Beta-decay. In 1956, Wu conceived and initiated the experiment of Cobalt-60, which, together with other two experiments, eventually proved the asymmetry of parity in weak-interactions, a hypothesis proposed by T. D. Lee and C. N. Yang. The importance of the experiment gained Wu an enormous reputation which spread even to China, when this was a period of hostility in Sino-American relations, and near total isolation due to the Cold-War. Wu was the daughter of a revolutionary, and an activist in college in patriotic student movements, and she combined this background with her scientific career as the way of ``Saving China with Science,'' a common belief reflecting the Zeitgeist of her time. Although she spent most of her life in the U.S., Wu never wavered in her love for or loyalty to her motherland. Her patriotism, as well as her scientific achievement, made Wu a legend in China, being called ``the Chinese Madam Curie.'' Even during the Cultural Revolution, a novel supposedly taking Wu as the original model was very popular in underground circles, widely spread by hand-written-copies. From 1979-1988, the CUSPEA program enrolled hundreds of China's best graduate students into physics departments in American universities. Although Wu herself was not

  2. [Liivimaa valgustaja August Wilhelm Hupel 1737- 1819] / Kai Reemann

    Index Scriptorium Estoniae

    Reemann, Kai

    2010-01-01

    Eesti Looduseuurijate Selts raamatukogu juhataja Kai Reemann tutvustab nii raamatukogu kui ka 2004. aastal parimaks ajalooraamatuks tunnistatud teost "Liivimaa valgustaja August Wilhelm Hupel 1737- 1819" (Tallinn, 2004)

  3. O tempora, o mores! / Maria-Kristiina Lotman, Kai Tafenau

    Index Scriptorium Estoniae

    Lotman, Maria-Kristiina, 1974-

    2011-01-01

    Tutvustus: Sallustius. Catilina vandenõu / Gaius Sallustius Crispus ; ladina keelest tõlkinud Maria-Kristiina Lotman ja Kai Tafenau. Tallinn : Tallinna Ülikooli Kirjastus, 2011. (Bibliotheca antiqua (Tallinna Ülikool))

  4. [The essence of Professor Wu Lian-Zhong's acupuncture manipulation].

    Science.gov (United States)

    Liu, Jing; Guo, Yi; Wu, Lian-Zhong

    2014-05-01

    The painless needle insertion technique, summarized by Professor WU Lian-zhong during his decades of acupuncture clinical practice is introduced in this article, which is characterized as soft, flexible, fast, plucking and activating antipathogenic qi. The Sancai (three layers) lifting and thrusting manipulation technique is adopted by Professor WU for getting the qi sensation. And features of 10 kinds of needling sensation such as soreness, numbness, heaviness, distension, pain, cold, hot, radiation, jumping and contracture are summarized. Finger force, amplitude, speed and time length are also taken as the basis of reinforcing and reducing manipulations. Moreover, examples are also given to explain the needling technique on some specific points which further embodies Professor WU's unique experiences and understandings on acupuncture.

  5. Yin Zhi Huang and other plant-derived preparations: where herbal and molecular medicine meet

    NARCIS (Netherlands)

    Elferink, Ronald Oude

    2004-01-01

    Yin Zhi Huang, a decoction of Yin Chin (Artemisia capillaris) and three other herbs, is widely used in Asia to prevent and treat neonatal jaundice. We recently identified the constitutive androstane receptor (CAR, NR113) as a key regulator of bilirubin clearance in the liver. Here we show that

  6. Neuroprotective mechanism of Kai Xin San: upregulation of hippocampal insulin-degrading enzyme protein expression and acceleration of amyloid-beta degradation

    Directory of Open Access Journals (Sweden)

    Na Wang

    2017-01-01

    Full Text Available Kai Xin San is a Chinese herbal formula composed of Radix Ginseng , Poria , Radix Polygalae and Acorus Tatarinowii Rhizome . It has been used in China for many years for treating amnesia. Kai Xin San ameliorates amyloid-β (Aβ-induced cognitive dysfunction and is neuroprotective in vivo , but its precise mechanism remains unclear. Expression of insulin-degrading enzyme (IDE, which degrades Aβ, is strongly correlated with cognitive function. Here, we injected rats with exogenous Aβ42 (200 μM, 5 μL into the hippocampus and subsequently administered Kai Xin San (0.54 or 1.08 g/kg/d intragastrically for 21 consecutive days. Hematoxylin-eosin and Nissl staining revealed that Kai Xin San protected neurons against Aβ-induced damage. Furthermore, enzyme-linked immunosorbent assay, western blot and polymerase chain reaction results showed that Kai Xin San decreased Aβ42 protein levels and increased expression of IDE protein, but not mRNA, in the hippocampus. Our findings reveal that Kai Xin San facilitates hippocampal Aβ degradation and increases IDE expression, which leads, at least in part, to the alleviation of hippocampal neuron injury in rats.

  7. [Professor WU Zhongchao's experience of penetration needling].

    Science.gov (United States)

    Zhang, Ning; Wang, Bing; Zhou, Yu

    2016-08-12

    Professor WU Zhongchao has unique application of penetration needling in clinical treatment. Professor WU applies penetration needling along meridians, and the methods of penetration needling include self-meridian penetration, exterior-interior meridian penetration, identical-name meridian penetration, different meridian penetration. The meridian differentiation is performed according to different TCM syndromes, locations and natures of diseases and acupoint nature, so as to make a comprehensive assessment. The qi movement during acupuncture is focused. In addition, attention is paid on anatomy and long-needle penetration; the sequence and direction of acupuncture is essential, and the reinforcing and reducing methods have great originality, presented with holding, waiting, pressing and vibrating. Based on classical acupoint, the acupoint of penetration needling is flexible, forming unique combination of acupoints.

  8. Muusikud on koolitatud palgamõrvareiks / Kai Kallastu ; interv. Karol Kallas

    Index Scriptorium Estoniae

    Kallastu, Kai, 1970-

    2007-01-01

    Lauljanna oma eelseisvast esietendusest : Pärnu mudaravilas esietendub täna Sven Kivisildniku audiovisuaalne ooperietendus "Topeltwagner juustuga", teostajaks lavastuse meeskond REPOO ENSEMBLE (Kivisildnik, Andrus ja Kai Kallastu, Indrek ja Leonora Palu, Rein Laos)

  9. Hotelli Radisson SAS mantra : jah, ma saan! / Kai Vare

    Index Scriptorium Estoniae

    Vare, Kai, 1968-

    2004-01-01

    Radisson SAS hotell Tallinnas on kliendirahulolu-uuringute järgi keti hotellide seas esimeste hulgas. Hotelli direktor Kaido Ojaperv ja müügijuht Ann-Kai Tõrs Radisson SAS-i standarditest, kliendi sajaprotsendilise rahulolu tagamise põhimõtetest, personali valikust, koolitusest. Kommenteerib Sandra Dimitrovich

  10. Lattice models and integrability: a special issue in honour of F Y Wu

    Science.gov (United States)

    Guttmann, A. J.; Jacobsen, J. L.

    2012-12-01

    Fa Yueh (Fred) Wu was born on 5 January 1932 in Nanking (now known as Nanjing), China, the capital of the Nationalist government. Wu began kindergarten in 1937 in a comfortable setting, as his father held a relatively high government position. But the Sino-Japanese war broke out in July 1937, and Nanking fell to Japanese hands in November. Fleeing the Japanese, his parents brought Wu to their hometown in Hunan, and then to the war capital Chungking (now Chongqing) in 1938, where they lived for eight years until the end of the war. Around that time the Japanese began bombing Chungking, and Wu's childhood memories were dominated by air raids, bombings and burning not dissimilar to those experienced by Londoners during the war. At times the air raids lasted for days disrupting everyday lives in Chungking, including Wu's schooling. One day during a fierce bombing raid, a bomb fell in their garden reducing a pavilion and the surrounding pond to a huge crater; another bomb fell just a few metres from the tunnel where his family took shelter, almost sealing the only entrance. The family moved the very next day to the countryside. As a result of the war, Wu attended seven schools before finishing his primary education. Fortunately, by the time he entered junior high school in 1943, the Japanese forces were on the wane and Wu entered the elite middle school, Nankai. His early academic performance in Nankai seemed to him mediocre, but he nevertheless impressed his geometry teacher by showing bursts of talent. With hindsight, this early interest in geometry may have led to his later insights in graphical analyses of statistical systems. The family returned to Nanking in 1946 after the Victory over Japan Day. By this time his father had become elected to the Legislative Yuan, the equivalent of the US Senate. Wu entered high school in Nanking in 1946. Since he came from an elite school in Chungking, he excelled in most of his classes, especially mathematics. Notwithstanding his

  11. Videoinstallatsiooni aeg pole ümber : muljeid Amsterdami videofestivalilt / Kai Kaljo

    Index Scriptorium Estoniae

    Kaljo, Kai, 1959-

    1999-01-01

    17. World Wide Video Festival 15.-20. IX Amsterdamis Melkwegi keskuses ja Stedelijki muuseumis. Väljapanekust. Kai Kaljolt oli videofestivalil väljas 'One Way to See America'. Seminaride materjalid: wwvf@wwvf.demon ja www.wwvf.nl

  12. http://dx.doi.org/10.4314/ajtcam.v10i4.6

    African Journals Online (AJOL)

    AJTCAM

    http://dx.doi.org/10.4314/ajtcam.v10i4.6. 36. CHEMOTHERAPEUTIC ACTIVITIES OF CARTHAMI FLOS AND ITS REVERSAL EFFECT ON. MULTIDRUG RESISTANCE IN CANCER CELLS. Jimmy Yiu-Cheong Wu*a, Zhi-Ling Yub, Wang-Fun Fongb, Yi-Qian Shia. aZhejiang Chinese Medical University, Hangzhou 310053, ...

  13. The Species Identity of the Widely Cultivated Ganoderma, ‘G. lucidum’ (Ling-zhi), in China

    Science.gov (United States)

    Wang, Xin-Cun; Xi, Rui-Jiao; Li, Yi; Wang, Dong-Mei; Yao, Yi-Jian

    2012-01-01

    Ling-zhi, a widely cultivated fungus in China, has a long history in traditional Chinese medicine. Although the name ‘Ganoderma lucidum’, a species originally described from England, has been applied to the fungus, their identities are not the same. This study aims to clarify the identity of this medicinally and economically important fungus. Specimens of Ling-zhi from China (field collections and cultivated basidiomata of the Chinese ‘G. lucidum’), G. lucidum from UK and other related Ganoderma species, were examined both morphologically and molecularly. High variability of basidioma morphology was found in the cultivated specimens of the Chinese ‘G. lucidum’, while some microscopic characters were more or less consistent, i.e. short clavate cutis elements, Bovista-type ligative hyphae and strongly echinulate basidiospores. These characters were also found in the holotype of G. sichuanense, a species originally described from Sichuan, China, and in recent collections made in the type locality of the species, which matched the diagnostic characters in the prologue. For comparison, specimens of closely related species, G. lucidum, G. multipileum, G. resinaceum, G. tropicum and G. weberianum, were also examined. DNA sequences were obtained from field collections, cultivated basidiomata and living strains of the Chinese ‘G. lucidum’, specimens from the type locality of G. sichuanense, and specimens of the closely related species studied. Three-gene combined analyses (ITS+IGS+rpb2) were performed and the results indicated that the Chinese ‘G. lucidum’ shared almost identical sequences with G. sichuanense. Based on both morphological and molecular data, the identity of the Chinese ‘G. lucidum’ (Ling-zhi) is considered conspecific with G. sichuanense. Detailed morphological descriptions and illustrations are provided in addition to discussion of nomenclature implications. PMID:22911713

  14. Cisplatin Induces Up-Regulation of KAI1, a Metastasis Suppressor ...

    African Journals Online (AJOL)

    HP

    including breast, testicular, ovarian, cervical, prostate, head and neck, ..... Vertebral bone metastasis in breast cancer: a case report. Rom J Morphol Embryol 2011; 52: 897-. 905. ... KAI1/CD82 on the β1 integrin maturation in highly migratory ...

  15. Effect of healthy Qigong “WuQinXi” exercise on peripheral blood T ...

    African Journals Online (AJOL)

    USER

    2010-07-19

    Jul 19, 2010 ... cell subgroups in elderly “WuQinXi” practitioners. Fifty healthy Chinese ... on health condition, diet, medical history, lifestyle and menstrual status, .... Mechanism of health-promotion of “WuQinXi” exercise created in East Hai ...

  16. The HANS KAI Project: a community-based approach to improving health and well-being through peer support

    Directory of Open Access Journals (Sweden)

    Alexandra Henteleff

    2018-03-01

    Full Text Available Introduction: HANS KAI is a unique health promotion intervention to improve participants’ health by focussing on interrelated chronic disease prevention behaviours through peer support and strengthening of social support networks. The study objective was to determine the effectiveness of HANS KAI in an urban Canadian setting. Methods: We used a mixed methods intervention research design that involved multiple sites from November 2010 to April 2015. Data was obtained from participant surveys as well as in-person interviews at zero, 6, 12 and 24 months. Participants met in groups at least once a month during the research period, to self-monitor health indicators, prepare and share a healthy snack, participate in a physical activity, set a healthy lifestyle goal (optional and socialize. Results: There were statistically significant mental health improvements from pre- to post-program, and 66% of the participants described specific behaviour changes as a result of HANS KAI participation. Additional positive health impacts included peer support; acquiring specific health knowledge; inspiration, motivation or accountability; the empowering effect of monitoring one’s own health indicators; overcoming social isolation and knowing how to better access services. Conclusion: The need to identify innovative ways to address chronic disease prevention and management has been the driver for implementing and evaluating HANS KAI. While further research will be required to validate the present findings, it appears that HANS KAI may be an effective approach to create environments that empower community members to support each other while promoting healthy lifestyle choices and detecting early changes in health status.

  17. Kai Kaljo : Autsaiderist staar = Star Outsider / Mari Laaniste

    Index Scriptorium Estoniae

    Laaniste, Mari, 1977-

    2007-01-01

    Vitraaži õppinud Kai Kaljost kui tänapäevasest installatsioonikunstnikust, kelle loomingut iseloomustab irooniline lähenemine eksistentsiaalsetele teemadele ja kes kodumaal on pikka aega "mittesoovitud" olnud. Maailmavaatlemise ja hetketabamise kõrval on tal hinge peal ka kunsti positsioon ühiskonnas ja ühiskonna suhtumine kunstnikku, ta on varmas osutama ümbritseva maailma vildakatele väärtushinnangutele ja eetilisele ambivalentsusele

  18. Effects of Compound Yi-Zhi on D-galactose-induced learning and memory deficits in mice

    Institute of Scientific and Technical Information of China (English)

    XUJiang-Ping; WUHang-Yu; LILin

    2004-01-01

    AIM: To explore the effects of Compound Yi-Zhi (YZC) on learning and memory capacity and free radical metabolism in D-galactose induced mice dementia model. METHODS: The mice dementia model was induced by a daily D-galactose 0.15g/kg sc for 45 days and after 5 days'D-galactose injection, the mice were treated with three doses of YZC

  19. Browse Title Index

    African Journals Online (AJOL)

    Items 501 - 550 of 1309 ... HH Tamboura, B Bayala, M Lompo, IP Guissou, L Sawadogo ... X Wang, Y-G Chen, L Ma, Z-H Li, J-Y Li, X-G Liu, J-L Zou, J-H Wu. Vol 11, No 2 ... Zhi-Jiang Wang, Wei Xu, Jian-Wen Liang, Cai-Sheng Wang, Yani Kang.

  20. Ray Wu as Fifth Business: Deconstructing collective memory in the history of DNA sequencing.

    Science.gov (United States)

    Onaga, Lisa A

    2014-06-01

    The concept of 'Fifth Business' is used to analyze a minority standpoint and bring serious attention to the role of scientists who play a galvanizing role in a science but for multiple reasons appear less prominently in more common recounts of any particular development. Biochemist Ray Wu (1928-2008) published a DNA sequencing experiment in March 1970 using DNA polymerase catalysis and specific nucleotide labeling, both of which are foundational to general sequencing methods today. The scant mention of Wu's work from textbooks, research articles, and other accounts of DNA sequencing calls into question how scientific collective memory forms. This alternative history seeks to understand why a key figure in nucleic acid sequence analysis has remained less visibly connected or peripheral to solidifying narratives about the history of DNA sequencing. The study resists predictable dismissals of Wu's work in order to seriously examine the formation of his nucleic acid sequence analysis research program and how he shared his knowledge of sequencing during a period of rapid advancement in the field. An analysis of Wu's work on sequencing the cohesive ends of lambda bacteriophage in the 1960s and 1970s exemplifies how a variety of individuals and groups attempted to develop protocol for sequencing the order of nucleotide base pairs comprising DNA. This historical examination of the sociality of scientific research suggests a way to understand how Wu and others contributed to the very collective memory of DNA sequencing that Wu eventually tried to repair. The study of Wu, who was a Chinese immigrant to the United States, provides a foundation for further critical scholarship on the heterogeneous histories of Asian American bioscientists, the sociality of their scientific works, and how the resulting knowledge produced is preserved, if not evenly, in a scientific field's collective memory. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Interlopers, Rogues, or Cosmopolitans? Wu Jianzhang and Early Modern Commercial Networks on the China Coast

    Directory of Open Access Journals (Sweden)

    Peter C. Perdue

    2017-12-01

    Full Text Available After the First Opium War (1839–1842, British and American merchants negotiated with Chinese officials in Shanghai to work out the framework of the new treaty port regime. One key player in these negotiations was Wu Jianzhang, a Cantonese merchant who became circuit intendant of the Shanghai region. Wu, however, also had links to Cantonese sailors and anti-Qing secret societies. When the Small Swords Society took Shanghai in 1853, he found himself entangled in conflicting responsibilities and networks. Foreign traders and Chinese officials regarded Wu, like other middlemen on the Chinese coast, with a mixture of respect and distrust. Wu’s situation, however, was not unique to the mid-nineteenth century. This article compares Wu to other intermediaries who played similar roles in the sixteenth and late nineteenth centuries, in order to show the ways in which Wu, his predecessors, and those who followed in his footsteps connected China to the wider world by navigating the treacherous waters of diplomacy, war, and commerce. The work of John K. Fairbank, who in the 1950s pioneered the study of such people as Wu Jianzhang, can find new meaning in the twenty-first century, enabling us to understand the transnational implications of China’s local social history.

  2. On soliton solutions of the Wu-Zhang system

    Directory of Open Access Journals (Sweden)

    Inc Mustafa

    2016-01-01

    Full Text Available In this paper, the extended tanh and hirota methods are used to construct soliton solutions for the WuZhang (WZ system. Singular solitary wave, periodic and multi soliton solutions of the WZ system are obtained.

  3. We Can't Get No (Life) Satisfaction? Comment on Oswald and Wu (2010)

    Science.gov (United States)

    Pesta, Bryan J.; McDaniel, Michael A.; Bertsch, Sharon

    2010-01-01

    Oswald and Wu (2010; "Science") recently reported life satisfaction ranks for residents of the 50 U.S. states. Their rankings were framed as measures of "well-being," but were derived from responses to only a single survey item ("In general, how satisfied are you with your life?"). Here we contrast Oswald and Wu's subjective rankings with our…

  4. Modeled Oceanic Response and Sea Surface Cooling to Typhoon Kai-Tak

    Directory of Open Access Journals (Sweden)

    Yu-Heng Tseng

    2010-01-01

    Full Text Available An ocean response to typhoon Kai-Tak is simulated using an accurate fourth-order, basin-scale ocean model. The surface winds of typhoon Kai-Tak were obtained from QuikSCAT satellite images blended with the ECMWF wind fields. An intense nonlinear mesoscale eddy is generated in the northeast South China Sea (SCS with a Rossby number of O(1 and on a 50 - 100 km horizontal scale. Inertial oscillation is clearly observed. Advection dominates as a strong wind shear drives the mixed layer flows outward, away from the typhoon center, thus forcing upwelling from deep levels with a high upwelling velocity (> 30 m day-1. A drop in sea surface temperature (SST of more than 9°C is found in both observation and simulation. We attribute this significant SST drop to the influence of the slow moving typhoon, initial stratification and bathymetry-induced upwelling in the northeast of the SCS where the typhoon hovered.

  5. Karrikin-KAI2 signalling provides Arabidopsis seeds with tolerance to abiotic stress and inhibits germination under conditions unfavourable to seedling establishment.

    Science.gov (United States)

    Wang, Lu; Waters, Mark T; Smith, Steven M

    2018-05-04

    The control of seed germination in response to environmental conditions is important for plant success. We investigated the role of the karrikin receptor KARRIKIN INSENSITIVE2 (KAI2) in the response of Arabidopsis seeds to osmotic stress, salinity and high temperature. Germination of the kai2 mutant was examined in response to NaCl, mannitol and elevated temperature. The effect of karrikin on germination of wild-type seeds, hypocotyl elongation and the expression of karrikin-responsive genes was also examined in response to such stresses. The kai2 seeds germinated less readily than wild-type seeds and germination was more sensitive to inhibition by abiotic stress. Karrikin-induced KAI2 signalling stimulated germination of wild-type seeds under favourable conditions, but, surprisingly, inhibited germination in the presence of osmolytes or at elevated temperature. By contrast, GA stimulated germination of wild-type seeds and mutants under all conditions. Karrikin induced expression of DLK2 and KUF1 genes and inhibited hypocotyl elongation independently of osmotic stress. Under mild osmotic stress, karrikin enhanced expression of DREB2A, WRKY33 and ERF5 genes, but not ABA signalling genes. Thus, the karrikin-KAI2 signalling system can protect against abiotic stress, first by providing stress tolerance, and second by inhibiting germination under conditions unfavourable to seedling establishment. © 2018 The Authors. New Phytologist © 2018 New Phytologist Trust.

  6. Non-minimal Wu-Yang monopole

    International Nuclear Information System (INIS)

    Balakin, A.B.; Zayats, A.E.

    2007-01-01

    We discuss new exact spherically symmetric static solutions to non-minimally extended Einstein-Yang-Mills equations. The obtained solution to the Yang-Mills subsystem is interpreted as a non-minimal Wu-Yang monopole solution. We focus on the analysis of two classes of the exact solutions to the gravitational field equations. Solutions of the first class belong to the Reissner-Nordstroem type, i.e., they are characterized by horizons and by the singularity at the point of origin. The solutions of the second class are regular ones. The horizons and singularities of a new type, the non-minimal ones, are indicated

  7. Towards a Collective Intelligence: Transmediality and the Wu Ming Project

    Directory of Open Access Journals (Sweden)

    Melina Anne Masterson

    2014-11-01

    Full Text Available Dagli albori della Seconda Repubblica in Italia,  le strategie di dominio sui mass media dell’ex premier Silvio Berlusconi hanno avuto un effetto considerevole sull’immaginario culturale italiano. In un approccio multisensoriale e multimediale alla scrittura, il collettivo Wu Ming mette in questione i paradigmi culturali che negli ultimi venti anni sono diventati egemonici. L’esperienza di un romanzo dei Wu Ming va ben oltre la parola stampata poiché cerca di stimolare tutti i cinque sensi per arricchire il modo in cui il lettore vive quello che c’è sulla pagina, dimostrando esempi chiari della «convergence culture» coniata da Henry Jenkins. Questo saggio esamina l’interazione tra parola e immagine messa in atto dal collettivo tramite il sito Pinterest e illustra come questo aspetto del loro progetto rappresenti un microcosmo di un approccio complessivo alla creazione estetica e alla pratica culturale. Inoltre, questo saggio descrive in che modo il processo collettivo di consumo portato avanti dai Wu Ming contribuisca alla formazione delle «communities of sentiment» di Arjun Appadurai e alla «intelligenza collettiva» di Jenkins. Queste sono formazioni che rivitalizzano il concetto di cultura popolare per la nostra epoca digitale e offrono un’alternativa ad un immaginario culturale italiano sovra-determinato dalle pratiche del Berlusconismo.

  8. Georgi söögituba Väike-Maarjas / Kai Tort, Ilmar Aasumets

    Index Scriptorium Estoniae

    Tort, Kai

    2006-01-01

    7 ill.; Georg Lurichi järgi nime saanud söögituba asub arhitekt Alar Kotli vanaisale kuulunud hoones; söögitoa kujunduse tegi Kai Tort, mööbli valmistasid kohalikud puusepad, plekist lambid - Ilmar Aasumets, omanik Avo Part

  9. Effects of Capsule Yi -Zhi on learning and memory disorder and beta-amyloid peptide induced neurotoxicity in rats

    Institute of Scientific and Technical Information of China (English)

    XUJiang-Ping; WUHang-Yu; LILin

    2004-01-01

    AIM To investigate the effects of Capsule Yi-Zhi (CYZ) on learning and memory disorder and beta-amyloid protein induced neurotoxieity in rats. Methods Various doses of CYZ were administered to Sprague-Dawley (SD) rats for 8 days, twice a day. Then scopolamine hydrobromide (Sco) intraperitoneal injection was performed on each rat and the

  10. Protection of nucleated bone marrow cells of mice against effect of radiation-induced micronucleus formation by using polysaccharides extracted from 'Zi Zhi' (a ganoderma)

    International Nuclear Information System (INIS)

    Chu Fang; Luo Houliang; Luo Gui; Chen Shunle; Liu Zhifang

    1988-01-01

    This paper describes the influence of polysaccharides extracted from 'Zi Zhi' (Ganoderma Sinese Zhao, Xu et Zhang) on the frequency of micronucleated cells induced by 60 Co gamma irradiation at different doses in bone marrow of mice. These polysaccharides of 'Zi Zhi' were shown to be of ability to protect nucleated bone marrow cells from micronucleus formation in irradiated mice. For Swiss mice, a dose reduction factor (DRF) was found to be 1.72 in the range of 0 to 4.728 Gy and for LACA mice, to be 1.73 in the range of 0 to 3.152 Gy. Such findings indicate that these polysaccharides are comparable to L-cysteine in their effeciency of protection

  11. Kai Adolf Jensen, professor i almindelig patologi

    DEFF Research Database (Denmark)

    Høiby, Niels

    2016-01-01

    for the Bacillus Calmette-Guérin vaccine production and supervised many young scientists’ doctoral theses on the aspects of tuberculosis. He became internationally recognized, and he revealed an important scientific fraud in the laboratory of the Austrian professor Ernst Löwenstein (1878-1950), who claimed that he...... could detect M. tuberculosis in blood cultures as a cause of a multitude of diseases. He was a pioneer in eradication of bovine tuberculosis in Denmark which became the first country in the world where this happened. Kai Adolf Jensen held the position as professor of general pathology from 1940 to 1965...

  12. The Hintermann-Merlini-Baxter-Wu and the infinite-coupling-limit Ashkin-Teller models

    Energy Technology Data Exchange (ETDEWEB)

    Huang Yuan, E-mail: huangy22@mail.ustc.edu.cn [Hefei National Laboratory for Physical Sciences at Microscale and Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Deng Youjin, E-mail: yjdeng@ustc.edu.cn [Hefei National Laboratory for Physical Sciences at Microscale and Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Jacobsen, Jesper Lykke, E-mail: jacobsen@lpt.ens.fr [Laboratoire de Physique Theorique, Ecole Normale Superieure, 24 rue Lhomond, 75231 Paris (France); Universite Pierre et Marie Curie, 4 place Jussieu, 75252 Paris (France); Salas, Jesus, E-mail: jsalas@math.uc3m.es [Grupo de Modelizacion, Simulacion Numerica y Matematica Industrial, Universidad Carlos III de Madrid, Avda. de la Universidad 30, 28911 Leganes (Spain); Grupo de Teorias de Campos y Fisica Estadistica, Instituto Gregorio Millan, Universidad Carlos III de Madrid, Unidad asociada al IEM-CSIC, Madrid (Spain)

    2013-03-11

    We show how the Hintermann-Merlini-Baxter-Wu model (which is a generalization of the well-known Baxter-Wu model to a general Eulerian triangulation) can be mapped onto a particular infinite-coupling-limit of the Ashkin-Teller model. We work out some mappings among these models, also including the standard and mixed Ashkin-Teller models. Finally, we compute the phase diagram of the infinite-coupling-limit Ashkin-Teller model on the square, triangular, hexagonal, and kagome lattices.

  13. Governing Civil Service Pay in China, by Alfred M. Wu. Copenhagen: NIAS Press, 2014. xvi+236 pp

    DEFF Research Database (Denmark)

    Brødsgaard, Kjeld Erik

    2016-01-01

    Book review of: Governing Civil Service Pay in China by Alfred M. Wu. Copenhagen: NIAS Press, 2014.......Book review of: Governing Civil Service Pay in China by Alfred M. Wu. Copenhagen: NIAS Press, 2014....

  14. Wu-Ling-San formula prophylaxis against recurrent calcium oxalate ...

    African Journals Online (AJOL)

    Wu-Ling-San (WLS) formula has been proved to prevent calcium oxalate nephrolithiasis both in vitro and in vivo. This is the first prospective, randomized and placebo-controlled clinical trial of WLS in calcium oxalate nephrolithiasis prevention. All patients who enrolled were asked to drink enough fluid to urinate at least 2 L ...

  15. Himaalaja naised eesti naiste silmade läbi / Kai Herkel ; interv. Reet Varblane

    Index Scriptorium Estoniae

    Herkel, Kai

    2004-01-01

    Visuaalantropoloogiline väljapanek "Oskus olla õnnelik arenevas maailmas" Kastellaanimajas 24. märtsini. Väljas on fotod Tiibeti ja Ladakhi küladest, mägedest ja inimestest. Fotograaf Kai Herkeli, tibetoloog Natalia Munatajeva ja tiibeti munga Konchok Sangyas' kangelane on sealne naine. Piltide kõrval on suur tähtsus tekstil

  16. HBCU Equipment for AFOSR Project 13RSL012: The Mechanism by which ADP Regulates the Structure and Function of the Protein KaiC

    Science.gov (United States)

    2015-05-18

    FTE Equivalent: Total Number: Discipline Yassamin Ihat 0.00 Human biology Montana Altman 0.00 Human biology Michael Montoya 0.00 Human biology 0.00 3...cycles of day and night, because they evolved timekeeping systems called circadian clocks, which regulate biological activities with ~24- h rhythms 1...which together generate a circadian (~24 h ) rhythm of KaiC autophosphorylation, drives the clock of cyanobacteria 13, 14 . We have discovered that KaiB

  17. Effects of Gui Zhi Ma Huang Ge Ban Tang on the TLR7 Pathway in Influenza Virus Infected Mouse Lungs in a Cold Environment.

    Science.gov (United States)

    Qin, Hong-Qiong; Shi, Shan-Shan; Fu, Ying-Jie; Yan, Yu-Qi; Wu, Sha; Tang, Xiao-Long; Chen, Xiao-Yin; Hou, Guang-Hui; Jiang, Zhen-You

    2018-01-01

    We wished to investigate the effects of the traditional Chinese medicine Gui Zhi Ma Huang Ge Ban Tang on controlling influenza A virus (IAV) infection and improving inflammation in mouse lungs. Mice were maintained in normal and cold environments and infected with IAV by intranasal application, respectively. Real-time quantitative polymerase chain reaction was used to measure mRNA expression of TLR7, myeloid differentiation primary response 88 (MyD88), and nuclear factor-kappa B (NF- κ B)p65 in the TLR7 signaling pathway and virus replication in lungs. Western blotting was used to measure expression levels of TLR7, MyD88, and NF- κ B p65 proteins. Flow cytometry was used to detect the proportion of T-helper (Th)1/Th2 and Th17/T-regulatory (Treg) cells. Application of Gui Zhi Ma Huang Ge Ban Tang in influenza-infected mice in a cold environment showed (i) downregulation of TLR7, MyD88, and NF- κ Bp65; (ii) inhibition of transcriptional activities of promoters coding for TLR7, MyD88, and NF- κ Bp65; (iii) reduction in the proportion of Th1/Th2 and Th17/Treg cells. Gui Zhi Ma Huang Ge Ban Tang had a good therapeutic effect on mice infected with IAV, especially in the cold environment. It could reduce lung inflammation in mice significantly and elicit an anti-influenza effect by downregulating expression of the key factors in TLR7 signaling pathway.

  18. Rahvaliitlaste rahalaevad roostetavad kai ääres / Sten-Aleks Pihlak

    Index Scriptorium Estoniae

    Pihlak, Sten-Aleks

    2007-01-01

    Rahvaliidule lähedal seisvad ärimehed müüsid riigile maha vanu kalalaevu, et neid õppelaevadena kasutada, kuid nüüd roostetavad laevad kai ääres. Vt. samas: Lobby ekstraklass - minister tegi kõik, mis soovitud; Kalurite liit on tänaseks laiali jooksnud; Undrest jr võitles toetuse välja kohtus; Üheksast õppelaevaks muudetud alusest õpitakse päriselt vaid mõnel. Küsimustele vastab endine põllumajandusminister Ester Tuiksoo. Kommenteerivad Toivo Orgussaar ja Jüri Lember

  19. Nonindigenous marine species at Waikiki and Hawaii Kai, Oahu, Hawaii in 2001 - 2002 (NODC Accession 0001061)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Surveys of the marine algae, invertebrates and reef fishes of Waikiki and the Kuapa Pond and Maunalua Bay areas of Hawaii Kai were conducted with the objective of...

  20. Nonindigenous Marine Species at Waikiki and Hawaii Kai, Oahu, Hawaii in 2001-2002 (NODC Accession 0001061)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Surveys of the marine algae, invertebrates and reef fishes of Waikiki and the Kuapa Pond and Maunalua Bay areas of Hawaii Kai were conducted with the objective of...

  1. Combinatorial interpretation of Haldane-Wu fractional exclusion statistics.

    Science.gov (United States)

    Aringazin, A K; Mazhitov, M I

    2002-08-01

    Assuming that the maximal allowed number of identical particles in a state is an integer parameter, q, we derive the statistical weight and analyze the associated equation that defines the statistical distribution. The derived distribution covers Fermi-Dirac and Bose-Einstein ones in the particular cases q=1 and q--> infinity (n(i)/q-->1), respectively. We show that the derived statistical weight provides a natural combinatorial interpretation of Haldane-Wu fractional exclusion statistics, and present exact solutions of the distribution equation.

  2. Rap and Resistance: A Social Movement of the Wu-Tang Clan.

    Science.gov (United States)

    Chasteen, Amy L.; Shriver, Thomas

    1998-01-01

    Examines specific collective identity and political expression of the rap group the Wu-Tang Clan. Reveals a multi-layered political strategy that has been conscientiously designed and implemented to instigate a social movement. Prioritizes the voices of marginalized Black peoples and provides raw narratives about oppression. (MMU)

  3. Tulevik on helge: noortele meeldib ettevõtlikkus / Evelin Org, Marge Rahu, Kai Isand ... [jt.

    Index Scriptorium Estoniae

    2016-01-01

    Sokos Hotels Tallinna müügi- ja turundusdirektori Evelin Orgi, kohviku Maitsvad Muffinid omaniku Marge Rahu, Garage48 SA tegevjuhi Kai Isanda, Swedbanki juriidilise divisjoni direktori Riho Roopõllu, Nortali tegevjuhi ja juhatuse liikme Andre Kulli, Veriff tegevjuhi ja asutaja Kaarel Kotkase ning Esteloni kaasasutaja ja partneri, Eesti Era- ja Riskikapitali Assotsiatsiooni tegevjuhi Kristiina Vassilkova mõtteid edukusest

  4. Spent Mushroom Waste as a Media Replacement for Peat Moss in Kai-Lan (Brassica oleracea var. Alboglabra Production

    Directory of Open Access Journals (Sweden)

    H. Sendi

    2013-01-01

    Full Text Available Peat moss (PM is the most widely used growing substrate for the pot culture. Due to diminishing availability and increasing price of PM, researchers are looking for viable alternatives for peat as a growth media component for potted plants. A pot study was conducted with a view to investigate the possibility of using spent mushroom waste (SMW for Kai-lan (Brassica oleracea var. Alboglabra production replacing peat moss (PM in growth media. The treatments evaluated were 100% PM (control, 100% SMW, and mixtures of SMW and PM in different ratios like 1 : 1, 1 : 2, and 2 : 1 (v/v with/without NPK amendment. The experiment was arranged in a completely randomized design with five replications per treatment. Chemical properties like pH and salinity level (EC of SMW were within the acceptable range of crop production but, nutrient content, especially nitrogen content was not enough to provide sufficient nutrition to plant for normal growth. Only PM (100% and SMW and PM mixture in 1 : 1 ratio with NPK amendment performed equally in terms of Kai-lan growth. This study confirms the feasibility of replacing PM by SMW up to a maximum of 50% in the growth media and suggests that NPK supplementation from inorganic sources is to ensure a higher productivity of Kai-lan.

  5. Mellin-Barnes regularization, Borel summation and the Bender-Wu asymptotics for the anharmonic oscillator

    International Nuclear Information System (INIS)

    Kowalenko, V.; Rawlinson, A.A.

    1998-01-01

    We introduce the numerical technique of Mellin-Barnes regularization, which can be used to evaluate both convergent and divergent series. The technique is shown to be numerically equivalent to the corresponding results obtained by Borel summation. Both techniques are then applied to the Bender-Wu formula, which represents an asymptotic expansion for the energy levels of the anharmonic oscillator. We find that this formula is unable to give accurate values for the ground state energy, particularly when the coupling is greater than 0.1. As a consequence, the inability of the Bender-Wu formula to yield exact values for the energy level of the anharmonic oscillator cannot be attributed to its asymptotic nature. (authors)

  6. A representative prescription for emotional disease, Ding-Zhi-Xiao-Wan restores 5-HT system deficit through interfering the synthesis and transshipment in chronic mild stress-induced depressive rats.

    Science.gov (United States)

    Dong, Xian-Zhe; Li, Zhao-Liang; Zheng, Xiao-Li; Mu, Li-Hua; Zhang, Gang-qiang; Liu, Ping

    2013-12-12

    Ding-Zhi-Xiao-Wan (DZ, also known as Kai-Xin-San) is a famous traditional Chinese medicine used for the treatment of emotional disease. Previously, we have found that in a variety of animal models of depression (such as tail suspension model, model of chronic fatigue and forced swimming model) DZ demonstrated significant antidepressant behavior and promoted the production of 5-hydroxytryptamine (5-HT). However, the mechanisms of 5-HT regulation are still unclear. Therefore, the current study is designed to further investigate the antidepressant effect of DZ by observing its influence on 5-HT synthesis, metabolism, transport and other key links, so as to clarify the molecular mechanism of its 5-HT regulation. Solitary rising combined with the chronic unpredictable mild stress (CMS) was used to establish the rat model of depression. The rats were given DZ for 3 weeks, the behavior change and the following items in hippocampus and prefrontal cortex were detected simultaneously: 5-HT, 5-hydroxyindoleacetic acid (5-HIAA), tryptophan hydroxylase (TPH), aromatic amino acid decarboxylase (AADC), monoamine oxidase (MAO) and 5-HT transporter (5-HTT) were observed. Our results showed that treatment with the DZ significantly improved the behavior and simultaneously increased the 5-HT level in the hippocampus, prefrontal cortex tissues and hippocampus extracellular of depressive rats. In future studies revealed that DZ could significantly increase the protein and mRNA expression of the key enzymes TPH during the 5-HT synthesis process in the hippocampus and prefrontal cortex of the depressed rats, and suppress the expression of 5-HTT protein and mRNA at the same time. But it had no effects on MAO-A and MAO-B activities. We believe that antidepressant effect of DZ is caused by the increase of 5-HT synthesis and reduction of 5-HT re-uptake, and eventually increase the content of 5-HT in the brain and the synaptic gaps. © 2013 Published by Elsevier Ireland Ltd.

  7. Biodesulfurization of Naphthothiophene and Benzothiophene through Selective Cleavage of Carbon-Sulfur Bonds by Rhodococcus sp. Strain WU-K2R

    Science.gov (United States)

    Kirimura, Kohtaro; Furuya, Toshiki; Sato, Rika; Ishii, Yoshitaka; Kino, Kuniki; Usami, Shoji

    2002-01-01

    Naphtho[2,1-b]thiophene (NTH) is an asymmetric structural isomer of dibenzothiophene (DBT), and in addition to DBT derivatives, NTH derivatives can also be detected in diesel oil following hydrodesulfurization treatment. Rhodococcus sp. strain WU-K2R was newly isolated from soil for its ability to grow in a medium with NTH as the sole source of sulfur, and growing cells of WU-K2R degraded 0.27 mM NTH within 7 days. WU-K2R could also grow in the medium with NTH sulfone, benzothiophene (BTH), 3-methyl-BTH, or 5-methyl-BTH as the sole source of sulfur but could not utilize DBT, DBT sulfone, or 4,6-dimethyl-DBT. On the other hand, WU-K2R did not utilize NTH or BTH as the sole source of carbon. By gas chromatography-mass spectrometry analysis, desulfurized NTH metabolites were identified as NTH sulfone, 2′-hydroxynaphthylethene, and naphtho[2,1-b]furan. Moreover, since desulfurized BTH metabolites were identified as BTH sulfone, benzo[c][1,2]oxathiin S-oxide, benzo[c][1,2]oxathiin S,S-dioxide, o-hydroxystyrene, 2-(2′-hydroxyphenyl)ethan-1-al, and benzofuran, it was concluded that WU-K2R desulfurized NTH and BTH through the sulfur-specific degradation pathways with the selective cleavage of carbon-sulfur bonds. Therefore, Rhodococcus sp. strain WU-K2R, which could preferentially desulfurize asymmetric heterocyclic sulfur compounds such as NTH and BTH through the sulfur-specific degradation pathways, is a unique desulfurizing biocatalyst showing properties different from those of DBT-desulfurizing bacteria. PMID:12147483

  8. On the de Rham–Wu decomposition for Riemannian and Lorentzian manifolds

    International Nuclear Information System (INIS)

    Galaev, Anton S

    2014-01-01

    It is explained how to find the de Rham decomposition of a Riemannian manifold and the Wu decomposition of a Lorentzian manifold. For that it is enough to find parallel symmetric bilinear forms on the manifold, and do some linear algebra. This result will allow to compute the connected holonomy group of an arbitrary Riemannian or Lorentzian manifold. (paper)

  9. Madame Wu Chien-Shiung the first lady of physics research

    CERN Document Server

    Chiang, Tsai-Chien

    2014-01-01

    Narrating the well-lived life of the "Chinese Madame Curie" - a recipient of the first Wolf Prize in Physics (1978), the first woman to receive an honorary doctorate from Princeton University, as well as the first female president of the American Physics Society - this book provides a comprehensive and honest account of the life of Dr. Chien-Shiung Wu, an outstanding and leading experimental physicist of the 20th century.

  10. Kaasaegse Kunsti Eesti Keskus kui kunstidiiler / Rael Artel, Kai Kaljo, Marco Laimre, Marge Monko ; intervjueerinud Reet Varblane

    Index Scriptorium Estoniae

    2010-01-01

    Vestlusringis osalenud vabakutseline kuraator Rael Artel, Tallinna Ülikooli dotsent, kunstnik Kai Kaljo, EKA fotoosakonna professor, kunstnik Marco Laimre ja EKA fotoosakonna dotsent, kunstnik Marge Monko arutavad, millist rolli peaks KKEK täitma praegu, 21. sajandi teisel kümnendil avatud maailma tingimustes

  11. The Academic Profession and University Governance Participation in Japan: Focusing on the Role of Kyoju-kai

    Science.gov (United States)

    Yonezawa, Akiyoshi

    2014-01-01

    The dominant role of Kyoju-kai (the professoriate) in university governance in Japan is now facing a critical examination as part of university reforms in response to global competition. What are the determinants of the characteristics of participation in university governance by individual faculty members? In what way does the organizational…

  12. Art, class and gender in Joseon dynasty Korea: representations of lower-class women by the scholar-painter Yun Duseo.

    Science.gov (United States)

    Chung, Saehyang P

    2011-01-01

    This paper examines several pioneering genre paintings by the important scholar painter Yun Duseo (1668-1715), with its focus on their artistic sources which have not yet been explored so far. Painted on ramie, 'Women Picking Potherbs' is one of the most intriguing examples among Yun Duseo's oeuvre, which encompasses a broad variety of themes, including genre imagery, landscapes, portraits, dragons, and horses. Even among Yun Duseo's genre paintings, 'Women Picking Potherbs' is extraordinary, as recent scholarship regards it as the earliest independent representation of lower-class women in the history of Korean art. In particular, Yun Duseo painted two women who were working ourdoors to gather spring potherbs. In a conservative Confucian society, it was extraordinary women who were working outdoors. Hence, Yun Duseo occupies a highly important place in Korean painting. Furthermore, even though Yun Duseo came from the upper-class, he often painted images of lower class people working. It is possible that Yun Duseo was familiar with the book titled "Tian gong kai wu" (Exploitation of the Works of Nature) which was published in the 17th century. By identifying the probable body of his artistic sources in the book known as "Tian gong kai wu," it will be possible to assess the innovations and limitations found in 'Women Picking Potherbs'.

  13. PLE-wu, a new member of piggyBac transposon family from insect, is active in mammalian cells.

    Science.gov (United States)

    Wu, Chunxiao; Wang, Shu

    2014-10-01

    piggyBac, a highly active transposon in insect and mammalian cells, is a very useful tool in genome manipulation. A new piggyBac-like element (PLE), named PLE-wu, was identified from a mutant baculovirus cultured in sf9 insect cells. This new transposon is 2931 bp in length and encodes two active forms of transposase, a 708-amino acid-long transposase and a short 576-residue-long transposase translated from a downstream in-frame initiation codon. PLE-wu has asymmetric terminal structures, containing 6-bp inverted terminal repeats, 32-bp imperfect inverted and direct sub-terminal repeats. Similar to piggyBac, PLE-wu exhibits traceless excision activity in both insect and mammalian cells, restoring the original TTAA target sequence upon excision. It also retains the insertion activity in mammalian cells with a plasmid to chromosome transposition rate about 10-fold higher than random integration. Plasmid rescue assays revealed that the TTAA target sequence was duplicated at the junctions of the insertion site. Deletion of the terminal sequences including the sub-terminal repeats decreased the transposition activity of the 708-residue-long transposase, while the transposition activity of the short form of transposase was not affected. With its low sequence similarity to piggyBac, PLE-wu will contribute to the understanding the mechanism of PLE transposition, as well as design of new transposon systems with higher activity. Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  14. Analysing the Wu metric on a class of eggs in Cn–II

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 127; Issue 3. Analysing the Wu metric on a class of eggs in C C n – I I .... G P BALAKUMAR1 PRACHI MAHAJAN2. Indian Statistical Institute, Chennai 600 113, India; Department of Mathematics, Indian Institute of Technology – Bombay, Mumbai 400 076, India ...

  15. Strength-based Supervision: Frameworks, Current Practice, and Future Directions A Wu-wei Method.

    Science.gov (United States)

    Edwards, Jeffrey K.; Chen, Mei-Whei

    1999-01-01

    Discusses a method of counseling supervision similar to the wu-wei practice in Zen and Taoism. Suggests that this strength-based method and an understanding of isomorphy in supervisory relationships are the preferred practice for the supervision of family counselors. States that this model of supervision potentiates the person-of-the-counselor.…

  16. Investigation of the Livengood–Wu integral for modelling autoignition in a high-pressure bomb

    NARCIS (Netherlands)

    Hu, Zhixin; Somers, Bart L.M.T.; Cracknell, Roger F.; Bradley, Derek

    2016-01-01

    The reaction progress variable, which is widely used in premixed and diffusion combustion studies, comprises a set of pre-selected intermediate species to denote reaction progress. Progress towards autoignition can also be traced by the Livengood–Wu (LW) integral. Autoignition occurs when the LW

  17. Maintenance of Glucose Homeostasis Through Acetylation of the Metabolic Transcriptional Coactivator PGC1-alpha

    Science.gov (United States)

    2011-02-01

    Salmenniemi, U., Ruotsalainen, E., Pihlajamaki, J., Vauhkonen, I., Kai - nulainen, S., Punnonen, K., Vanninen, E., and Laakso, M. (2004). Mul- tiple...cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 39, 359–407. Wang, Y.X., Zhang, C.L., Yu , R.T., Cho, H.K., Nelson, M.C., Bayuga- Ocampo...calorie diet, Nature 444 (2006) 337–342. [19] J.M. Wu, Z.R. Wang, T.C. Hsieh , J.L. Bruder, J.G. Zou, Y.Z. Huang, Mechanism of cardioprotection by

  18. Analysing the Wu metric on a class of eggs in ℂn – I

    Indian Academy of Sciences (India)

    G P BALAKUMAR

    An explicit description of the Wu metric on the Thullen domains (these are also ..... K(p,v), when p varies across Z. It suffices to focus attention on the case when p varies ... Substituting this into (6.3) and dividing throughout by ˜t2| ˆw|2p2. 1.

  19. Ignition delay time correlation of fuel blends based on Livengood-Wu description

    KAUST Repository

    Khaled, Fathi

    2017-08-17

    In this work, a universal methodology for ignition delay time (IDT) correlation of multicomponent fuel mixtures is reported. The method is applicable over wide ranges of temperatures, pressures, and equivalence ratios. n-Heptane, iso-octane, toluene, ethanol and their blends are investigated in this study because of their relevance to gasoline surrogate formulation. The proposed methodology combines benefits from the Livengood-Wu integral, the cool flame characteristics and the Arrhenius behavior of the high-temperature ignition delay time to suggest a simple and comprehensive formulation for correlating the ignition delay times of pure components and blends. The IDTs of fuel blends usually have complex dependences on temperature, pressure, equivalence ratio and composition of the blend. The Livengood-Wu integral is applied here to relate the NTC region and the cool flame phenomenon. The integral is further extended to obtain a relation between the IDTs of fuel blends and pure components. Ignition delay times calculated using the proposed methodology are in excellent agreement with those simulated using a detailed chemical kinetic model for n-heptane, iso-octane, toluene, ethanol and blends of these components. Finally, very good agreement is also observed for combustion phasing in homogeneous charge compression ignition (HCCI) predictions between simulations performed with detailed chemistry and calculations using the developed ignition delay correlation.

  20. Suan Zao Ren Tang in Combination with Zhi Zi Chi Tang as a Treatment Protocol for Insomniacs with Anxiety: A Randomized Parallel-Controlled Trial

    OpenAIRE

    Hu, Lin-lin; Zhang, Xin; Liu, Wen-juan; Li, Mei; Zhang, Yong-hua

    2015-01-01

    Insomnia is a serious worldwide health problem that is often comorbid with anxiety. The purpose of the present study was to evaluate the efficacy of a Chinese formula containing Suan Zao Ren Tang (SZRT) and Zhi Zi Chi Tang (ZZCT; SZR-ZZC) for improving sleep quality and anxiety states with four indices of Polysomnography (PSG), the Insomnia Severity Index (ISI), the Pittsburgh Sleep Quality Index (PSQI), and the Self Rating Anxiety Scale (SAS). Methods. A randomized, parallel-controlled trial...

  1. Why Study Chinese Classics and How to Go about It: Response to Zongjie Wu's "Interpretation, Autonomy, and Transformation--Chinese Pedagogic Discourse in Cross-Cultural Perspective"

    Science.gov (United States)

    Tan, Sor-Hoon

    2011-01-01

    This response to Zongjie Wu's "Interpretation, autonomy, and interpretation" focuses on the "battle between East and West" which contextualizes Wu's proposal to counter the current Western domination of Chinese pedagogic discourse with an "authentic language" recovered from the Chinese classics. It points out that it…

  2. Can Medical Herbs Stimulate Regeneration or Neuroprotection and Treat Neuropathic Pain in Chemotherapy-Induced Peripheral Neuropathy?

    Directory of Open Access Journals (Sweden)

    Sven Schröder

    2013-01-01

    Full Text Available Chemotherapy-induced neuropathy (CIPN has a relevant impact on the quality of life of cancer patients. There are no curative conventional treatments, so further options have to be investigated. We conducted a systematic review in English and Chinese language databases to illuminate the role of medical herbs. 26 relevant studies on 5 single herbs, one extract, one receptor-agonist, and 8 combinations of herbs were identified focusing on the single herbs Acorus calamus rhizoma, Cannabis sativa fructus, Chamomilla matricaria, Ginkgo biloba, Salvia officinalis, Sweet bee venom, Fritillaria cirrhosae bulbus, and the herbal combinations Bu Yang Huan Wu, modified Bu Yang Huan Wu plus Liuwei Di Huang, modified Chai Hu Long Gu Mu Li Wan, Geranii herba plus Aconiti lateralis praeparata radix , Niu Che Sen Qi Wan (Goshajinkigan, Gui Zhi Jia Shu Fu Tang (Keishikajutsubuto, Huang Qi Wu Wu Tang (Ogikeishigomotsuto, and Shao Yao Gan Cao Tang (Shakuyakukanzoto. The knowledge of mechanism of action is still limited, the quality of clinical trials needs further improvement, and studies have not yielded enough evidence to establish a standard practice, but a lot of promising substances have been identified. While CIPN has multiple mechanisms of neuronal degeneration, a combination of herbs or substances might deal with multiple targets for the aim of neuroprotection or neuroregeneration in CIPN.

  3. Professor Ta-You Wu and his ideas of science

    International Nuclear Information System (INIS)

    Ye Minghan; Dai Nianzu

    2005-01-01

    The career of Professor Ta-You Wu and his contributions in the latter half of his life in Taiwan, China are briefly reviewed. The authors focus our discussion on some of his ideas in pushing forward the advancement of science and technology in Taiwan and in promoting scientific standards. These ideas include: emphasis on the importance of basic science and qualified personnel as the foundation for the development of science and technology, and while advocating applied science he pointed out that 'future profits depend on high technology'. Thus, he contributed greatly to the rise of the economy in Taiwan. His view of the dispute between Bohr and Einstein is also briefly reviewed, as well as his principles of leadership as the president of Academia Sinica, Taiwan. (author)

  4. Designing and Implementing the Intranet for ZhuHai State-Kai Polymer and New Materials Co.,Ltd

    OpenAIRE

    Chen, Si; Jiang, Min

    2010-01-01

    This Thesis was commissioned by Zhuhai State-Kai Polymer and New Materials company, which is a chemical and pharmacy SME in China. The Thesis aimed to design and implement the Intranet with the characteristics of the case company on the basis of the identified requirements. The designed Intranet innovates in a computerized system to replace the current manual system used in its business life. The questionnaire approach was used to gather the information and requirements both from the view...

  5. The complete mitochondrial genome of a stonefly species, Kamimuria chungnanshana Wu, 1948 (Plecoptera: Perlidae).

    Science.gov (United States)

    Wang, Kai; Ding, Shuangmei; Yang, Ding

    2016-09-01

    This study determined the complete mitochondrial (mt) genome of the stonefly, Kamimuria chungnanshana Wu, 1948. The mt genome is 15, 943 bp in size and contains 37 canonical genes which include 22 transfer RNA genes, 13 protein-coding genes, and two ribosomal RNA genes, the control region is 1062 bp in length. The phylogenetic tree shows that Kamimuria chungnanshana is sister group of Kamimuria wangi.

  6. Identification and comparative quantification of bio-active phthalides in essential oils from si-wu-tang, fo-shou-san, radix angelica and rhizoma chuanxiong.

    Science.gov (United States)

    Tang, Yuping; Zhu, Min; Yu, Sheng; Hua, Yongqing; Duan, Jin-Ao; Su, Shulan; Zhang, Xu; Lu, Yin; Ding, Anwei

    2010-01-15

    Phthalides are important bio-active constituents in Si-Wu-Tang and Fo-Shou-San, two commonly used Traditional Chinese Medicine (TCM) combined prescriptions mainly derived from Radix Angelica and Rhizoma Chuanxiong. In this paper, the contents of eight phthalides, including Z-ligustilide, E-ligustilide, Z-butylenephthalide, E-butylene-phthalide, 3-butylphthalide, neocnidilide and senkyunolide A were determined or estimated by gas chromatography-mass spectrometry (GC-MS). The results showed GC-MS was a simple, rapid, and high sensitive method for analyzing phthalides in Si-Wu-Tang, Fo-Shou-San, Radix Angelica and Rhizoma Chuanxiong, and the extractable contents of each phthalides including Z-ligustilide, E-ligustilide, Z-butylenephthalide, etc. varied after Radix Angelica, Rhizoma Chuanxiong were combined into a formulation, such as Si-Wu-Tang and Fo-Shou-San. Furthermore, inhibition activity of essential oils from Si-Wu-Tang, Fo-Shou-San, Radix Angelica and Rhizoma Chuanxiong on uterine contraction was tested in an in vitro assay, and the results showed that the activity of the essential oil is higher as the content of the phthalides increase, which demonstrated that phthalides are possibly main active components inhibiting mice uterine contraction in vitro. All of the results suggested that comparative analysis of chemical components and pharmacological activities of each herb and formula is possibly helpful to elucidate the active components in traditional Chinese medicine, and to reveal the compatibility mechanism of TCM formulae.

  7. Ultra high performance liquid chromatography coupled with electrospray ionization/quadrupole time-of-flight mass spectrometry for the rapid analysis of constituents in the traditional Chinese medicine formula Wu Ji Bai Feng Pill.

    Science.gov (United States)

    Duan, Shengnan; Qi, Wen; Zhang, Siwen; Huang, Kunkun; Yuan, Dan

    2017-10-01

    An ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry method in both positive and negative ion modes was established in order to comprehensively investigate the major constituents in Wu Ji Bai Feng Pill. Briefly, a Waters ACQUITY UPLC HSS C 18 column was used to separate the aqueous extract of Wu Ji Bai Feng Pill. A total of 0.1% formic acid in acetonitrile and 0.1% aqueous formic acid v/v were used as the mobile phase. All analytes were determined using quadrupole time-of-flight mass spectrometry with electrospray ionization source in positive and negative ion modes. At length, a total of 173 components including flavones and their glycosides, monoterpene glycosides, triterpene saponins, phenethylalchohol glycosides, iridoid glycosides, phthalides, tanshinones, phenolic acids, sesquiterpenoids and cyclopeptides were identified or tentatively characterized in Wu Ji Bai Feng Pill in an analysis of 16.0 min based on the accurate mass and tandem mass spectrometry behaviors. The developed method is rapid and highly sensitive to characterize the chemical constituents of Wu Ji Bai Feng Pill, which could not only be used for chemical standardization and quality control of Wu Ji Bai Feng Pill, but also be helpful for further study in vivo metabolism of Wu Ji Bai Feng Pill. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Pertunjukan Teater Karo Hip Hop Kontemporer KAI

    Directory of Open Access Journals (Sweden)

    Silvia Anggreni Purba

    2013-11-01

    Pertunjukan Teater Karo Hip Hop Kontemporer KAI. The performance of Karo Theater collaborated with Hip Hop stems from a simple idea to collaborate Karo cultural traditions with popular culture. The performances can be enjoyed without having limitation on the language and culture. The process of combining two different cultures is a form of hybrid culture, and it may occur due to the globalization process. Through the process of deposition of the observations and strong impression, this performance is then brought into the form of Hip Hop as a preferred form which is energetic, personal and global. This performance is part of a modern tragedy with its destructive character which has explored the emotion and has presented it to the audiences. The exploration of Karo cultural tradition and Hip Hop dance as a language of symbols is able to reinforce words. The movement is not revealed by the verbal phrase but is presented through the movement of Hip Hop dance. The interpretation of the legend and texts into movement is carried out through the training process at the laboratory as a searching process and experiment, and afterward can be realized by considering the basic elements of Hip Hop, Karo cultural elements and performance. Karo Hip Hop Theatre is expected to become a preferred aesthetic form of a modern theater without losing its tradition form. Keyword: a contemporary Karo theater, Hip Hop, hybrid culture.

  9. Effects of electroacupuncture and electroacupuncture plus Tao Hong Si Wu Wan in treating primary dysmenorrhea.

    Science.gov (United States)

    Miao, Edwin Yong; Miao, Miranda Yi-mo; Kildea, Daniel George; Lao, Yi-Wen

    2014-02-01

    This study investigated the efficacies of electroacupuncture and electroacupuncture combined with Tao Hong Si Wu Wan in treating primary dysmenorrhea and compared the results with those obtained using conventional medical treatment. One treatment group, group 1, was administered Tao Hong Si Wu Wan (2625 mg) while the other, group 2, was administered a placebo (2625 mg) twice daily for 3 months. Electroacupuncture was used in both treatment groups: two sessions per menstrual cycle for three menstrual cycles. The reference group, group 3, was administered ibuprofen, 600 mg, twice daily, for five menstrual cycles. Uses of the herb, placebo and ibuprofen were blinded. A ridit analysis was used for testing and interpreting the effects of treatment. Pain intensity was determined using a qualitative grading method in a blinded manner. The ridit scores in groups 1 and 2 were significantly higher than those in reference group immediately after treatment and three months later. Twelve months after the treatment, group 1 had a higher ridit score than group 2. In comparison to the reference group, groups 1 and 2 achieved better menstrual pain relief both immediately and 3 months after treatment. In addition, group 1 had better long-term pain relief than group 2. Copyright © 2014. Published by Elsevier B.V.

  10. Phylogeography of Sophora moorcroftiana Supports Wu's Hypothesis on the Origin of Tibetan Alpine Flora.

    Science.gov (United States)

    Cheng, Shanmei; Qiong, La; Lu, Fan; Yonezawa, Takahiro; Yin, Ganqiang; Song, Zhiping; Wang, Yuguo; Yang, Ji; Zhang, Wenju

    2017-06-01

    Wu hypothesized that the Tibetan flora originated mostly from the paleotropical Tertiary flora in the Hengduan Mountains by adapting to the cold and arid environments associated with the strong uplift of the Qinghai-Tibet Plateau (QTP). Here, we combine the phylogeographic history of Sophora moorcroftiana with that of Sophora davidii to explore the speciation of S. moorcroftiana to test this hypothesis. We collected 151 individuals from 17 populations and sequenced 2 chloroplast fragments and the internal transcribed spacer of rDNA. Five chlorotypes and 9 ribotypes were detected but no significant phylogeographic structure was revealed. The integrated results of phylogeographic studies of these 2 species clearly support the progenitor-derivative relationship between them. We infer that the western peripheral population of S. davidii migrated westwards from the Hengduan Mountains to the middle reaches of the Yarlung Zangbo River and differentiated from its ancestor in the process of adaptation to increasingly cold and arid environments with the uplift of the QTP and finally evolved into S. moorcroftiana during the Late Pliocene. In addition, our findings shed light on the idea that natural selection, as imposed by climate differentiation (especially mean diurnal range and precipitation seasonality), directly drove this peripatric speciation event after geographic isolation. The speciation of S. moorcroftiana is a strong case supporting Wu's hypothesis about the origin of Tibet's flora. © The American Genetic Association 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  11. 31 july 2014 - H. WU Ambassador Permanent Representative of the People's Republic of China to the United Nations

    CERN Multimedia

    Egli, Laurent

    2014-01-01

    His Excellency Mr Hailong WU Ambassador Permanent Representative of the People's Republic of China to the United Nations Office at Geneva and other international organizations in Switzerland visiting the ATLAS cavern with ATLAS Spokesperson D. Charlton and the LHC tunnel at Point 1 with Technology Department, Vacuum, Surfaces and Coatings Group P. Cruikshank.

  12. Įvairių trąšų įtaka ekologiškai auginamiems žieminiams rugiams

    OpenAIRE

    Stelmokas, Svajūnas

    2009-01-01

    Lietuvos žemės ūkio universiteto Agroekologijos centro ekologinės gamybos ūkyje 2007-2008 m. atlikus fosforo ir kalio trąšų įtakos ekologiškai auginamiems žieminiams rugiams tyrimus nustatyta, kad didžiausias žieminių rugių derlingumas gautas tręšiant P60 fosforitmilčių norma. Didinant normą žieminių rugių derlingumas mažėjo. Lyginant fosforitmilčių normas tarpusavyje bei su netręštais žieminiais rugiais, esminių grūdų derlingumo skirtumų nenustatyta. Tręšimas fosforitmilčiais neturėjo esminė...

  13. Overexpression of the NADP+-specific isocitrate dehydrogenase gene (icdA) in citric acid-producing Aspergillus niger WU-2223L.

    Science.gov (United States)

    Kobayashi, Keiichi; Hattori, Takasumi; Hayashi, Rie; Kirimura, Kohtaro

    2014-01-01

    In the tricarboxylic acid (TCA) cycle, NADP(+)-specific isocitrate dehydrogenase (NADP(+)-ICDH) catalyzes oxidative decarboxylation of isocitric acid to form α-ketoglutaric acid with NADP(+) as a cofactor. We constructed an NADP(+)-ICDH gene (icdA)-overexpressing strain (OPI-1) using Aspergillus niger WU-2223L as a host and examined the effects of increase in NADP(+)-ICDH activity on citric acid production. Under citric acid-producing conditions with glucose as the carbon source, the amounts of citric acid produced and glucose consumed by OPI-1 for the 12-d cultivation period decreased by 18.7 and 10.5%, respectively, compared with those by WU-2223L. These results indicate that the amount of citric acid produced by A. niger can be altered with the NADP(+)-ICDH activity. Therefore, NADP(+)-ICDH is an important regulator of citric acid production in the TCA cycle of A. niger. Thus, we propose that the icdA gene is a potentially valuable tool for modulating citric acid production by metabolic engineering.

  14. A Response to Professor Wu Zongjie's "Interpretation, Autonomy, and Transformation: Chinese Pedagogic Discourse in a Cross-Cultural Perspective"

    Science.gov (United States)

    Curran, Thomas D.

    2014-01-01

    In response to an essay by Prof Wu Zongjie that was published in the "Journal of Curriculum Studies" [43(5), (2011), 569-590], I argue that, despite dramatic changes that have taken place in the language of Chinese academic discourse and pedagogy, evidence derived from the fields of psychology and the history of Chinese educational…

  15. [A Study on the quotations in the Wu xing da yi (The Gist of Five Phases) cited from Nei jing (Inner Canon)].

    Science.gov (United States)

    Wang, Zheng-Shan; Zhang, Qi-Cheng

    2013-07-01

    In the Wu xing da yi (The Gist of Five Phases), written by Xiao Ji of the Sui Dynasty, there were 9 quotations cited from Huang di nei jing (Inner Canon of Huangdi). By comparison with current version of Huang di nei jing, most of the descriptions are similar, yet still with some differences, such as yin-yang nature of the five zang visceras, the liver being the root of "pi ji", the spleen being the root of "cang lin" etc. Wu xing da yi epitomizes the books about yin-yang and five phases before the Sui Dynasty, while Xiao Ji's quotations from Huang di nei jing interpreted from the views of yin-yang and five phases, are different from the annotations of later ages.

  16. I Know You Are, But What Am I? : Anti-Individualism in the Development of Intellectual Humility and Wu-Wei

    NARCIS (Netherlands)

    Robinson, Brian; Alfano, M.R.

    2016-01-01

    Virtues are acquirable, so if intellectual humility is a virtue, it’s acquirable. But there is something deeply problematic—perhaps even paradoxical—about aiming to be intellectually humble. Drawing on Edward Slingerland’s analysis of the paradoxical virtue of wu-wei in Trying Not To Try, we argue

  17. Enzymatic characterization and gene identification of aconitate isomerase, an enzyme involved in assimilation of trans-aconitic acid, from Pseudomonas sp. WU-0701.

    Science.gov (United States)

    Yuhara, Kahori; Yonehara, Hiromi; Hattori, Takasumi; Kobayashi, Keiichi; Kirimura, Kohtaro

    2015-11-01

    trans-Aconitic acid is an unsaturated organic acid that is present in some plants such as soybean and wheat; however, it remains unclear how trans-aconitic acid is degraded and/or assimilated by living cells in nature. From soil, we isolated Pseudomonas sp. WU-0701 assimilating trans-aconitic acid as a sole carbon source. In the cell-free extract of Pseudomonas sp. WU-0701, aconitate isomerase (AI; EC 5.3.3.7) activity was detected. Therefore, it seems likely that strain Pseudomonas sp. WU-0701 converts trans-aconitic acid to cis-aconitic acid with AI, and assimilates this via the tricarboxylic acid cycle. For the characterization of AI from Pseudomonas sp. WU-0701, we performed purification, determination of enzymatic properties and gene identification of AI. The molecular mass of AI purified from cell-free extract was estimated to be ~ 25 kDa by both SDS/PAGE and gel filtration analyses, indicating that AI is a monomeric enzyme. The optimal pH and temperature of purified AI for the reaction were 6.0 °C and 37 °C, respectively. The gene ais encoding AI was cloned on the basis of the N-terminal amino acid sequence of the protein, and Southern blot analysis revealed that only one copy of ais is located on the bacterial genome. The gene ais contains an ORF of 786 bp, encoding a polypeptide of 262 amino acids, including the N-terminal 22 amino acids as a putative periplasm-targeting signal peptide. It is noteworthy that the amino acid sequence of AI shows 90% and 74% identity with molybdenum ABC transporter substrate-binding proteins of Pseudomonas psychrotolerans and Xanthomonas albilineans, respectively. This is the first report on purification to homogeneity, characterization and gene identification of AI. The nucleotide sequence of ais described in this article is available in the DDBJ/EMBL/GenBank nucleotide sequence databases under the Accession No. LC010980. © 2015 FEBS.

  18. Retracted: Long-term copper toxicity in apple trees (Malus pumila Mill) and bioaccumulation in fruits.

    Science.gov (United States)

    Sun, Bai-Ye; Kan, Shi-Hong; Zhang, Yan-Zong; Wu, Jun; Deng, Shi-Huai; Liu, Chun-Sheng; Yang, Gang

    2010-01-15

    The following article from Environmental Toxicology, 'Long-term Copper Toxicity in Apple Trees (Malus pumila Mill) and Bioaccumulation in Fruits' by Bai-Ye Sun, Shi- Hong Kan, Yan-Zong Zhang, Jun Wu, Shi-Huai Deng, Chun-Sheng Liu and Gang Yang, published online on January 15, 2010 in Wiley InterScience (www.interscience.wiley.com; DOI: 10.1002/tox.20565), has been retracted by agreement between the authors, the journal Editor in Chief, Dr. Paul Tchounwou, and Wiley Periodicals, Inc. The retraction has been agreed at the request of the authors due to overlap with 'Copper Toxicity and Bioaccumulation in Chinese Cabbage (Brassica pekinensis Rupr.)' by Zhi-Ting Xiong and Hai Wang, published in Environmental Toxicology, Volume 20, pages 188-194, 2005.

  19. [Professor WU Zhongchao's experience in the treatment of bi syndrome with fire needling therapy at lower he-sea points].

    Science.gov (United States)

    Zhou, Yu; Chen, Zhongjie; Liu, Chun; Wang, Bing; Zhang, Ning; Li, Caifen; Xie, Qian

    2016-07-12

    Bi syndrome is classified into five categories. Based on the syndrome differentiation of meridians and collaterals and zangfu theories, Professor WU Zhongchao proposed the fire needling therapy at the lower he -sea points for five types of bi syndromes. Professor WU stresses on the flexible application of fire needling therapy for bi syndrome at the lower he -sea points and innovated the unique five techniques of fire needling therapy, named lifting and threating needle of small amplitude at the lower he -sea points, the stimulation along the relevant meri-dians before fire needling, detecting the sensitive sites by gentle pressing the relevant lower he -sea points, combining the movement of affected upper limb or joint during fire needling, or combining with contralateral needling technique, and controlling the depth of fire needling based on the duration of sickness and depth of affected site. He pointed out that Shangjuxu (ST 37) is for skin bi syndrome, Zusanli (ST 36) for muscle bi syndrome, Yanglingquan (GB 34) for tendon bi syndrome, Weizhong (BL 40) for bone bi syndrome and Xiajuxu (ST 39) for vessel bi syndrome.

  20. Temporal Courses in EEG Theta and Alpha Activity in the Dynamic Health Qigong Techniques Wu Qin Xi and Liu Zi Jue

    Directory of Open Access Journals (Sweden)

    Diana Henz

    2018-01-01

    Full Text Available Health Qigong is a common technique of Traditional Chinese Medicine applied to strengthen mental and physical health. Several studies report increases in EEG theta and alpha activity after meditative Qigong techniques indicating a relaxed state of mind. To date, little is known on the effects of dynamic Health Qigong techniques that comprise bodily movements on brain activity. In the current study, we compared effects of two dynamic Health Qigong techniques on EEG brain activity. Subjects performed the techniques Wu Qin Xi (five animals play and Liu Zi Jue (six healing sounds in a within-subjects design. Eyes-open and eyes-closed resting EEG was recorded before and immediately after each 15-min practice block. Additionally, the Profile of Mood States (POMS questionnaire was administered at pretest, and after each 15-min practice block. Results show a decrease in alpha activity after 15 min, followed by an increase after 30 min in the Health Qigong technique Liu Zi Jue. Theta activity was decreased after 15 min, followed by an increase after 30 min in the technique Wu Qin Xi. Results of the POMS indicated an increased vigor-activity level with decreased fatigue and tension-anxiety levels in both techniques after 30 min of practice. Our results demonstrate different temporal dynamics in EEG theta and alpha activity for the Health Qigong techniques Wu Qin Xi and Liu Zi Jue. We hypothesize that the found brain activation patterns result from different attentional focusing styles and breathing techniques performed during the investigated Health Qigong techniques.

  1. Dark energy fingerprints in the nonminimal Wu-Yang wormhole structure

    Science.gov (United States)

    Balakin, Alexander B.; Zayats, Alexei E.

    2014-08-01

    We discuss new exact solutions to nonminimally extended Einstein-Yang-Mills equations describing spherically symmetric static wormholes supported by the gauge field of the Wu-Yang type in a dark energy environment. We focus on the analysis of three types of exact solutions to the gravitational field equations. Solutions of the first type relate to the model, in which the dark energy is anisotropic; i.e., the radial and tangential pressures do not coincide. Solutions of the second type correspond to the isotropic pressure tensor; in particular, we discuss the exact solution, for which the dark energy is characterized by the equation of state for a string gas. Solutions of the third type describe the dark energy model with constant pressure and energy density. For the solutions of the third type, we consider in detail the problem of horizons and find constraints for the parameters of nonminimal coupling and for the constitutive parameters of the dark energy equation of state, which guarantee that the nonminimal wormholes are traversable.

  2. Information Philosophy in China: Professor Wu Kun’s 30 Years of Academic Thinking in Information Philosophy

    Directory of Open Access Journals (Sweden)

    Guowu Li

    2011-10-01

    Full Text Available Professor Wu Kun, from Xi'an Jiaotong University of China, has been studying information philosophy for 30 years. He thinks information conception is one of the most fundamental areas in philosophy and has founded information philosophy. He has done original and pioneering research in information ontology, epistemology, social information theory, information production theory, information evolution theory, information value, and information thinking directions. He is the first scholar to develop a completely new view of theories, systems, and methods about information philosophy.

  3. Effect of “Jian-Pi-Zhi-Dong Decoction” on Gamma-Aminobutyric Acid in a Mouse Model of Tourette Syndrome

    Directory of Open Access Journals (Sweden)

    Wen Zhang

    2014-01-01

    Full Text Available The purpose of this study was to explore the positive effects of Jian-Pi-Zhi-Dong Decoction (JPZDD on Tourette syndrome (TS by investigating the expression of gamma-aminobutyric acid (GABA and its type A receptor (GABAAR in the striatum of a TS mice model. The model was induced by 3,3′-iminodipropionitrile (IDPN treatment; then mice were divided into 4 groups (n=22, each; control and IDPN groups were gavaged with saline and the remaining 2 groups were gavaged with tiapride and JPZDD. We recorded the stereotypic behaviors of TS mice and measured the content of GABA in striatum by HPLC and GABAAR expression by immunohistochemistry and real-time PCR. Our results showed that JPZDD inhibited the abnormal behaviors of TS model mice and decreased GABA levels and GABAAR protein and mRNA expression in the striatum of TS model mice. In brief, the mechanism by which JPZDD alleviates TS symptoms may be associated with GABAAR expression downregulation in striatum which may regulate GABA metabolism.

  4. Termiškai aktyvių membraninių tekstilės medžiagų plazminis apdorojimas siekiant superhidrofobiškumo

    Directory of Open Access Journals (Sweden)

    Adam TWARDOWSKI

    2012-06-01

    Full Text Available Specialios paskirties lauko drabužiai turi atitikti aukštus patvarumo, šiluminės ištaigos ir drėgmės pernašos reikalavimus. Šiems tikslams dažnai naudojamos membraninės termiškai aktyvios tekstilės medžiagos. Siekiant pagerinti šių tekstilės medžiagų išvaizda, gali būti naudojami įvairūs poveikiai, užtikrinantys superhidrofobinį savaime besivalantį paviršių (žinomą kaip lotoso efektas. Įgyvendinant šią idėją, buvo atlikti žėrinčiojo išlydžio radijo dažnio inertinių dujų bei angliavandenilių dujų plazmos poveikio pramoninėms medžiagoms tyrimai. Gauti geri rezultatai tiriant savaiminio valymosi savybes empiriškai, tam naudojant dulkes ir kietąsias daleles. Skirtingos poveikio sąlygos buvo lyginamos matuojant kontaktinį vandens drėkinimo kampą. Daugeliu atvejų paveiktų medžiagų kontaktinis kampas buvo gerokai didesnis nei pradinių medžiagų. Didžiausia kampo vertė siekė 155°. Paviršiaus ištirtas naudojant skenuojamąjį elektroninį mikroskopą (SEM bei SEM-EDX spektroskopiją. Silikoorganinių dujų plazma apdoroto pluošto paviršiuje aptiktas plonas būdingos sferinės struktūros sluoksnis.DOI: http://dx.doi.org/10.5755/j01.ms.18.2.1920

  5. A new species of Nemoura (Plecoptera: Nemouridae) from Jiangsu Province, China, with new illustrations for Nemoura nankinensis Wu.

    Science.gov (United States)

    Chen, Zhi-Teng; DU, Yu-Zhou

    2017-04-12

    A new species of Nemoura (Plecoptera: Nemouridae), N. fusiformis sp. nov. from Jiangsu Province, China, is described and illustrated. The new species is characterized by a strongly sclerotized large hook formed by outer margin of the outer lobe of the paraproct and by the outer sclerite of cercus with a sub-triangular medial process. The new species is compared with similar taxa. Additionally, supplementary illustrations for N. nankinensis Wu, 1926 are also provided.

  6. Identification of the Chemical Constituents in Aqueous Extract of Zhi-Qiao and Evaluation of Its Antidepressant Effect

    Directory of Open Access Journals (Sweden)

    Ming Wu

    2015-04-01

    Full Text Available The immature fruit of Citrus aurantium L. (Zhi-Qiao, ZQ has been used as a traditional medicine in China. Our previous study has shown that ZQ decoction may contribute to the antidepressant-like action of Chaihu-Shu-Gan-San. However, there are no reports on the chemical constituents of ZQ aqueous extract or its anti-depression effects. Firstly, this research reported the on-line identification of the chemical constituents in the aqueous extract of ZQ by coupling ultra-performance liquid chromatography/time-of-flight mass spectrometry (UPLC-Q-TOF/MS. A total of 31 chemical constituents were identified in ZQ aqueous extract, including one tannic acid, five flavones, 13 flavanones, one limonoid, three coumarins, three cyclic peptides, and five polymethoxylated flavonoids. The antidepressant effect of ZQ aqueous extract was evaluated in vivo and the results indicated that the mice immobility time during the forced swimming test and the tail suspension test were significantly reduced with ZQ treatment. MTT assays showed both ZQ aqueous extract and its major constituents (naringin, hesperidin, neohesperidin, and nobiletin had neuroprotective effect on corticosterone-induced neurotoxicity in PC12 cells. The in vivo and in vitro results suggest that ZQ has an antidepressant effect.

  7. The Anti-Inflammatory Effects of a Yin Zhi Huang Soup in an Experimental Autoimmune Prostatitis Rat Model

    Directory of Open Access Journals (Sweden)

    Longsheng Deng

    2017-01-01

    Full Text Available The present study aimed to investigate the therapeutic effects of the Chinese herbal medicine Yin Zhi Huang soup (YZS in an experimental autoimmune prostatitis (EAP rat model. In total, 48 rats were randomly divided into the following four groups (n=12/group: saline group, pathological model group, Qianlietai group, and YZS group. We determined the average wet weight of the prostate tissue, the ratio of the wet weight of the prostate tissue to body weight, tumor necrosis factor-alpha (TNF-α levels in the blood serum, the expression of inducible nitric oxide synthase (iNOS in the rats’ prostate tissues, and the pathological changes in the prostate tissue using light microscopy. YZS reduced the rats’ prostate wet weight, the ratio of the prostate wet weight to body weight, and TNF-α levels in the blood serum and inhibited the expression of iNOS in the rats’ prostate tissues (P<0.05. Following YZS treatment, the pathological changes in the rats’ prostates were improved compared with those in the model group (P<0.05. Furthermore, YZS treatment reduced inflammatory changes in the prostate tissue. It also significantly suppressed proinflammatory cytokines, such as TNF-α, and chemokines, such as iNOS, in the rat model of EAP.

  8. Dėl keleto retų vietovardžių kilmės (Greikónys, Grìkapėdis, Plasapnỹkai, Pušė́nai, Silgiónys, Tauliùkai, Vaĩsodžiai

    Directory of Open Access Journals (Sweden)

    Jonas Palionis

    2011-12-01

    Full Text Available ZUR ENSTEHUNG EINIGER SELTENER ORTSNAMEN (Greikónys, Grìkapėdis, Plasapnỹkai, Pušė́nai, Silgiónys, Tauliùkai, VaĩsodžiaiZusammenfassungIm vorliegenden Artikel werden sieben seltene Dorfnamen aus dem südlitauischen Gebiet behandelt. Die Analyse der Entstehung dieser Ortsnamen stützt sich vorwiegend auf das handschriftliche Material der Tauf- und Trauungsurkunden der zweiten Hälfte des 17. und der ersten Hälfte des 18. Jhs der Gemeinde Punià, die gegenwärtig dem Bezirks Alytùs angehört.Greikónys, die ältere Form ist bereits 1659 in einer Taufurkunde verzeichnet (de Gireykancow; das scheint eine Ableitung von dem Familiennamen *Gireika zu sein. Dieser Name läßt sich mit dem Verb gìrti ‘rühmen, loben’ in Verbindung setzen: *gireika- einer, der eine besondere Neigung sich zu rühmen aufweist, Prahlhans ist.Grìkapėdis ist, ohne Zweifel, ebenfalls anthroponymischen Ursprungs, da der Familienname Grìkpėdis im nordwestlichen Teil von Žemaitija vorkommt. Die Bedeutung der Komponenten dieses zusammengesetzten Familiennamens (grìkas ‘Buchweizen’ + pė́das ‘die Getreidegarbe’ zeigt eine metaphorische Basis der Entstehung des Kompositums. Die gegenwärtige Singularform ist wahrscheinlich eine spätere Bildung: in den Taufurkunden der zweiten Hälfte des 17. Jhs findet man Pluralformen (de Grikopedziow, de Grikiepedzow.Plasapnỹkai, änlich wie Greikonys und Grikapėdis, läßt ebenfalls einen anthroponymischen Ursprung vermuten, obwohl dies nicht so augenscheinlich ist. Dieser Ortsname konnte vom Familiennamen *Plasapnỹkas entstanden sein: *Plasapnỹkas < *plasa +  *upinykas, d. h. ‘ein an dem Fluß Plasãupė Wohnender’. Das erste Glied dieser kontrahierter Zusammensetzung könnte man auf eine Form des Verbs plàsti ‘breiter werden’ zurückführen.Pušė́nai kommt in der zweiten Hälfte des 17. und der ersten Hälfte des 18. Jhs als Puišėnai (de Puyszany vor. Diese ältere Form weist

  9. Prof. Wu Xiaoqiu:China Is Striving for the World's Most Developed Capital Market

    Institute of Scientific and Technical Information of China (English)

    Sun Yongjian; Zhang Yue

    2007-01-01

    @@ China's capital market is a hot issue in the new year. The best strategy to develop the Chinese capital market in the coming 15 to 20 years was discussed in the China Capital Market Forum, which was held in China at Renmin University on January 13. Government officials, scholars, and entrepreneurs commented that by 2020, the Chinese capital market will develop into one of the best capital markets in the world,not only in terms of size, but also asset quality, liquidity and dynamic trade. Is this a realistic goal? What steps should we take to pursue this target? With these questions in mind, after the forum, China's Foreign Trade interviewed Prof. Wu Xiaoqiu, Vice President of Renmin University of China,and the Director of the Finance & Securities Institute of Renmin University.

  10. Chinese herbal medicine compound Yi-Zhi-Hao pellet inhibits replication of influenza virus infection through activation of heme oxygenase-1

    Directory of Open Access Journals (Sweden)

    Jinqiu Yin

    2017-11-01

    Full Text Available As a leading cause of respiratory disease, influenza A virus (IAV presents a pandemic threat in annual seasonal outbreaks. Given the limitation of existing anti-influenza therapies, there remains to be a requirement for new drugs. Compound Yi-Zhi-Hao pellet (CYZH is a famous traditional Chinese medicine (TCM used in the clinic, whose formula has been recorded in Complication of National Standard for Traditional Chinese Medicine to treat common cold. In this study, we found that CYZH exhibited a broad-spectrum anti-influenza activity and inhibited the expression of viral RNA and proteins in vitro. Mechanistically, CYZH had no inhibitory activities against viral protein hemagglutinin and IAV RNA-dependent RNA polymerase. Instead, it induced activation of erythroid 2-related factor 2 (Nrf2 and nuclear factor kappa B (NF-κB, which subsequently upregulated heme oxygenase-1 (HO-1 expression. Also, CYZH protected cells from oxidative damage induced by reactive oxygen series. In conclusions, CYZH inhibits IAV replication in vitro, at least partly by activating expression of the Nrf2/HO-1 pathway.

  11. Tentative characterization of precursor compounds and co-factors of pigment formation in production of 'wu mi' from Vaccinium bracteatum Thunb. Leaves.

    Science.gov (United States)

    Fan, Mingcong; Fan, Yihui; Huang, Weiping; Wang, Li; Li, Yan; Qian, Haifeng; Zhang, Hui; Qi, Xiguang

    2018-10-01

    Vaccinium bracteatum leaves (VBTL) are traditionally used in China to dye rice grains, which assume a deep blue color, named 'Wu mi'. Information on the mechanism of pigment formation is limited. In this study, CIELAB color space parameters were used to represent the color of 'Wu mi'. Precursor compounds of pigments formed during the dyeing process were identified by UPLC Q-TOF MS analysis. The changes in co-factors for pigment formation in VBTL were measured at different growth stages. The L ∗ and b ∗ values of dyed rice increased as the leaves aged, whereas a ∗ values showed irregular changes. Six compounds were tentatively identified as pigment precursors by UPLC Q-TOF MS analysis. The pH and β-glucosidase activity at different growth stages of VBTL were indicated to be crucial co-factors for pigment formation. A tentative hypothesis is presented that iridoid glycosides are hydrolyzed by acids and β-glucosidases to form a dialdehyde structure that binds covalently with amino residues of lysine side chains in rice protein molecules. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. His Excellency Mr Ken WU Ambassador Extraordinary and Plenipotentiary of the People’s Republic of China to Switzerland

    CERN Multimedia

    Jean Claude Gadmer

    2011-01-01

    Photo 1-5:The delegation visiting the ATLAS visitor Center with P.Jenni, ATLAS Collaboration former Spokesperson Photo 6-14,15-20:visiting the ATLAS experimental area Photo 15:Y. YANG,Attaché-Q. WAN,First Secretary-Z. Ren,ATLAS Collaboration,High Energy Group,Shandong University-H.E. Mr K. Wu-P. Jenni-R. Voss,Adviser for the People’s Republic of China-H. FENG,Counsellor Photo 21-38:Signature of the Guest Book with CERN Director-General R. Heuer

  13. Clinical Effects and Safety of Zhi Sou San for Cough: A Meta-Analysis of Randomized Trials

    Directory of Open Access Journals (Sweden)

    Ningchang Cheng

    2017-01-01

    Full Text Available Introduction. Zhi Sou San (ZSS, a traditional Chinese prescription, has been widely applied in treating cough. The purpose of this meta-analysis was to evaluate the effectiveness and safety of ZSS for cough. Methods. We searched relevant articles up to 5 March 2017 in seven electronic databases: the Cochrane Central Register of Controlled Trials (CENTRAL, MEDLINE, PubMed, Chinese National Knowledge Infrastructure (CNKI, Cqvip Database (VIP, China Biology Medicine disc (CBM, and Wanfang Data. Randomized controlled trials (RCTs were eligible, regardless of blinding. The primary outcome was the total effective rate. Results. Forty-six RCTs with a total of 4007 participants were identified. Compared with western medicine, ZSS significantly improved the total effective rate (OR: 4.45; 95% CI: 3.62–5.47 and the pulmonary function in terms of FEV1 (OR: 0.35; 95% CI: 0.24–0.46 and decreased the adverse reactions (OR: 0.05; 95% CI: 0.02–0.01 and the recurrence rate (OR: 0.30; 95% CI: 0.16–0.57. However, there was no significant improvement in the cough symptom score comparing ZSS with western medicine. Conclusions. This meta-analysis shows that ZSS has significant additional benefits and relative safety in treating cough. However, more rigorously designed investigations and studies, with large sample sizes, are needed because of the methodological flaws and low quality of the included trials in this meta-analysis.

  14. Enhancement of carotenoid and chlorophyll content of an edible freshwater alga (Kai: Cladophora sp. by supplementary inorganic phosphate and investigation of its biomass production

    Directory of Open Access Journals (Sweden)

    Siripen Traichaiyaporn

    2012-01-01

    Full Text Available Enhancement of the carotenoid and chlorophyll content of an edible freshwater alga (Kai:Cladophora sp. by supplementary inorganic phosphate in canteen wastewater was investigated. Themass cultivation of the alga was conducted at ambient temperature and light intensity in dilutedcanteen wastewater enhanced with dipotassium hydrogen phosphate at 5-20 mg L-1. An increase intotal carotenoid and chlorophyll was observed. However, it had no effect on biomass production. Asa result of the algal cultivation, there was a dramatic improvement in the quality of canteen wastewater.

  15. Wu Shangshi: One of the outstanding founders of Chinese modern geography%吴尚时对中国近代地理学的贡献与学术思想探讨

    Institute of Scientific and Technical Information of China (English)

    陈吉余; 吴超羽; 司徒尚纪

    2017-01-01

    Wu Shangshi (1904-1947) is considered one of the outstanding modem geographers emerging in the early 20th century in China.It is partly a result of the introduction of modem sciences from the West.Wu graduated as a gold medalist in Sun Yat-sen University (SYU) in 1928.He was then granted scholarship to study geography in France.He studied at the University of Lyon and the University of Grenoble under the supervision of A.Allix,M.Pardé and R.Blanchard,who was one of the best known students of V.de la Blanche.In 1934,Wu finished his study in France and returned to SYU to serve as a professor of geography.He was head of the department in 1939-1945,the most difficult and perilous period during the Japanese invasion.The university moved constantly to flee the flames of war.The thousands of miles across south and south-west China became Wu's research field.To continue one's work under such circumstances required an extraordinary determination and dedication to science.Excessive hard work in tough environments ruined his health.Wu died in 1947 at the age of 43.Among the second generation of Chinese modem geographers,Wu was a rare example of an integrated geographer.He combined comprehensive and complex geographic thought with a balanced approach between holistic perspective and detailed research.In addition,he possessed an outstanding ability to conduct field work.As such,many of his research findings have withstood the test of time and remain relevant to this day.For instance,Wu proposed "one belt and three arcs" to summarize the distribution of the mountain ranges in China.On the long debates of the stratigraphic sequence of the red bed formations "Danxia" and "Nanxiong",Wu suggested an alternative viewpoint that the two formations could be deposited at approximately the same time but in different faces and it has been confirmed by modem geologic investigation some 50 years later.Both contributions were listed on the "Great Geographical Discoveries of China in 100

  16. Wu-Chia-Pi Solution Attenuates Carbon Tetrachloride-Induced Hepatic Injury through the Antioxidative Abilities of Its Components Acteoside and Quercetin

    Directory of Open Access Journals (Sweden)

    Ching-Chiung Wang

    2012-12-01

    Full Text Available Wu-Chia-Pi medicated wine, composed nine Chinese medicines soaked in 35% alcohol, is widely used in Asia for its health-promoting functions. However, long-term consumption of alcohol could result in liver dysfunction. In this study, Wu-Chia-Pi solution (WCPS and extract (WCPE were prepared by modification of the principals given by the Committee on Chinese Medicine and Pharmacy in Taiwan. The aim of this study was to explore the protective effect of WCPS against carbon tetrachloride (CCl4-induced liver injury and to clarify its active component(s. Antioxidative effects of the test samples were evaluated via MDA inhibition, catalase activity and DPPH-scavenging assays. HPLC was used to analysis the active components. Results showed that WCPS (1 and 5 mL/kg significantly prevented CCl4-induced liver injury without chronic liver toxicity. Referring to the antioxidative activities, WCPE displayed significant MDA inhibitory and DPPH-scavenging activities with IC50 values of 0.91 ± 0.03 and 0.60 ± 0.04 mg/mL, respectively. Catalase activity was also enhanced by treatment of WCPE, acteoside and quercetin. Therefore, we suggest that acteoside and quercetin are the major contributors to the antioxidative and hepatoprotective activities of WCPS, and a possible mechanism could be mediated through reduction of oxidative stress.

  17. Monte Carlo study of the pure and dilute Baxter-Wu model

    International Nuclear Information System (INIS)

    Schreiber, Nir; Adler, Joan

    2005-01-01

    We studied the pure and dilute Baxter-Wu (BW) models using the Wang-Landau (WL) sampling method to calculate the density-of-states (DOS). We first used the exact result for the DOS of the Ising model to test our code. Then we calculated the DOS of the dilute Ising model to obtain a phase diagram, in good agreement with previous studies. We calculated the energy distribution, together with its first, second and fourth moments, to give the specific heat and the energy fourth order cumulant, better known as the Binder parameter, for the pure BW model. For small samples, the energy distribution displayed a doubly peaked shape, and finite size scaling analysis showed the expected reciprocal scaling of the positions of the peaks with L. The energy distribution yielded the expected BW α = 2/3 critical exponent for the specific heat. The Binder parameter minimum appeared to scale with lattice size L with an exponent θ B equal to the specific heat exponent. Its location (temperature) showed a large correction-to-scaling term θ 1 = 0.248 ± 0.025. For the dilute BW model we found a clear crossover to a single peak in the energy distribution even for small sizes and the expected α = 0 was recovered

  18. Therapeutic effects of FuZhiSan on Alzheimer's disease rat model:evaluation with PET imaging

    International Nuclear Information System (INIS)

    Guo Zhe; Zhang Jinming; Yao Shulin; Feng Huiru; Li Xuling; Yin Dayi; Tian Jiahe

    2010-01-01

    Objective: To assess the feasibility of using PET molecular imaging to evaluate the therapeutic effects of traditional Chinese medicine FuZhiSan (FZS) on the model of aging Alzheimer's disease (AD) rats. Methods: Twenty aged AD rats (Sparague-Dawley rats,male) were randomly divided into FZS treated group (n = 10) and control group (n = 10). Another 10 healthy adult rats were as blank controls. Morris water maze record system was used for cognitive function assessment. Before and after FZS treatment 18 F-fluorodeoxyglucose (FDG) and 11 C-2- [4'-(methylamino) phenyl] benzothiazol-6-ol (PIB) PET imaging was undertaken. After post-treatment imaging procedures the brain tissues of all animals were taken for histochemical study, such as staining with HE, congo red, amyloid β (Aβ) immunofluorescence, 5-bromo-2-deoxyuridine (BrdU) immunofluorescence and NeuN immunofluorescence. Paired t-test was performed with SPSS 13.0 software for the data analysis. Results: The cognitive dysfunction of aging AD rats was improved after FZS treatment. The escape latency in FZS treated group was significantly shorter than that of control group ((32.5 ±10.8) s vs (102.6±8.8) s, t =15.7987, P=0. 0001). Diffuse neuronal loss and Aβ deposition were detected in the hippocampus and cortex in the aged AD rats. The imaging data showed that brain glucose metabolism was amended in FZS treated group while the abatement of amyloid deposition was not significant. Immunofluorescence results indicated that the neuronal proliferation was more remarkable in FZS treated group. Conclusions: It may be feasible to use PET imaging as a method to evaluate the therapeutic effect in AD rats. FZS may ameliorate memory dysfunction of aged AD rats. Its mechanism may be partly contributed to the enhancement of the neuronal proliferation and survival. (authors)

  19. Lanthanide metal-organic frameworks

    International Nuclear Information System (INIS)

    Cheng, Peng

    2015-01-01

    This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

  20. Lanthanide metal-organic frameworks

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Peng (ed.) [Nankai Univ., Tianjin (China). Dept. of Chemistry

    2015-03-01

    This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

  1. Bian Zheng Lun Zhi as a Complementary and Alternative Treatment for Menstrual Cramps in Women with Dysmenorrhea: A Prospective Clinical Observation

    Directory of Open Access Journals (Sweden)

    Pin-Yi Lin

    2014-01-01

    Full Text Available Background. Limited scientific evidence supports the positive effects of traditional Chinese medicine (TCM for treating dysmenorrhea. Thus, an observation period of 3 months could verify the ancient indication that TCM treatments effectively alleviate menstrual cramps in women with primary dysmenorrhea or endometriosis. Methods. A prospective, nonrandomized study (primary dysmenorrhea and endometriosis groups was conducted in women with dysmenorrhea for more than three consecutive menstrual cycles. All patients received TCM prescriptions based on bian zheng lun zhi theory 14 days before menstruation for a period of 12 weeks. Pain intensity was evaluated using a 10-cm visual analogue scale and two validated questionnaires (the Menstrual Distress Questionnaire and the World Health Organization Quality of Life questionnaire. Results. Of the initial 70 intent-to-treat participants, the women with dysmenorrhea reported significant alleviation of cramps during menstruation after the 12-week TCM treatment. Mixed model analysis revealed that TCM prescriptions were more effective in alleviating fatigue, hot flashes, dizziness, painful breasts, excitement, and irritability in the primary dysmenorrhea group (N=36 than in the endometriosis group (N=34. Conclusion. TCM prescriptions based on syndrome differentiation theory might be a potentially viable choice for treating painful menstruation and premenstrual symptoms after ruling out endometriosis.

  2. Orbinia wui, a new species from China, with redescription of O. dicrochaeta Wu, 1962 (Annelida, Orbiniidae).

    Science.gov (United States)

    Sun, Yue; Li, Xinzheng

    2018-04-04

    Two species of the genus Orbinia Quatrefages, 1865 are described including Orbinia dicrochaeta Wu, 1962 and Orbinia wui sp. n. The new species can easily be identified from other species in the genus by a combination of characters: branchiae first present from chaetiger 5, thoracic region with 14-16 chaetigers; first six thoracic neuropodia with 4-5 rows of uncini, with the last row short and curving ventral to anterior rows; subsequent thoracic neuropodia with four rows of subuluncini and one short row of uncini, arranged more densely than anterior chaetigers; both uncini and subuluncini surrounded by long sheath all of its length on concave side, sheath with developed transverse rows of barbs. This study suggests that the species of Orbinia may be divided into two groups. A taxonomic key and comparative table to all species of Orbinia is provided.

  3. Chang Kai-shek's “Humanitarian Bombs” and the Mirage Known as the “Manchurian-Mongolian Problem”: New Japanese-Language Perspectives on the Transnational History of Modern East Asia

    Directory of Open Access Journals (Sweden)

    Kyu Hyun Kim

    2014-06-01

    Full Text Available On May 20, 1938, two American-made Chinese airplanes—Martin B-10 monoplane bombers—took off from Ningbo, Fujian province, in the direction of southwestern Japan. Instead of dropping bombs, they released propaganda materials produced by the Nationalist Party (Guomindang, pleading with the industrial workers, farmers, and petty bourgeois citizens of Japan to stop fighting China and resist their militarist government. This “humanitarian bombardment,” masterminded by Chiang Kai-shek, is little known today—perhaps deservedly so, for it had its embarrassing features. For one, the planes never reached the strategically important areas and merely flew over sparsely populated regions of Kumamoto and Miyazaki prefectures. Further, the propaganda materials were either voluntarily turned over to or confiscated by the Japanese authorities almost as soon as they hit the ground. As far as we can tell, the operation had little impact on the Japanese attitude toward China or on the Second Sino-Japanese War (1937–1945... Iechika Ryōko 家近亮子,Shō Kaiseki no gaikō senryaku to Nitchū sensō 蒋介石の外交戦略と日中戦争[Chiang Kai-shek's diplomatic strategies and the Sino-Japanese War]. Tokyo: Iwanami Shoten, 2012. ISBN: 978-4-00-025865-4. Nakami Tatsuo 中見立夫, 'Manmō mondai' no rekishiteki kōzu 満蒙問題の歴史的構図 [The historical composition of the “Manchurian-Mongolian problem”]. Tokyo: Daigaku Shuppankai, 2013. ISBN: 978-4-86-337131-6.

  4. MRI-guided targeting delivery of doxorubicin with reduction-responsive lipid-polymer hybrid nanoparticles

    Directory of Open Access Journals (Sweden)

    Wu B

    2017-09-01

    Full Text Available Bo Wu,1,2 Shu-Ting Lu,1 Kai Deng,2 Hui Yu,2 Can Cui,2 Yang Zhang,2 Ming Wu,2 Ren-Xi Zhuo,2 Hai-Bo Xu,1 Shi-Wen Huang2 1Department of Radiology, Zhongnan Hospital of Wuhan University, 2Key Laboratory of Biomedical Polymers, Ministry of Education, Department of Chemistry, Wuhan University, Wuhan, People’s Republic of China Abstract: In recent years, there has been increasing interest in developing a multifunctional nanoscale platform for cancer monitoring and chemotherapy. However, there is still a big challenge for current clinic contrast agents to improve their poor tumor selectivity and response. Herein, we report a new kind of Gd complex and folate-coated redox-sensitive lipid-polymer hybrid nanoparticle (Gd-FLPNP for tumor-targeted magnetic resonance imaging and therapy. Gd-FLPNPs can simultaneously accomplish diagnostic imaging, and specific targeting and controlled release of doxorubicin (DOX. They exhibit good monodispersity, excellent size stability, and a well-defined core-shell structure. Paramagnetic nanoparticles based on gadolinium-diethylenetriaminepentaacetic acid-bis-cetylamine have paramagnetic properties with an approximately two-fold enhancement in the longitudinal relaxivity compared to clinical used Magnevist. For targeted and reduction-sensitive drug delivery, Gd-FLPNPs released DOX faster and enhanced cell uptake in vitro, and exhibited better antitumor effect both in vitro and in vivo. Keywords: redox-sensitive, tumor-targeted, gadolinium, contrast agents, PLGA

  5. Effect of kai xin san on learning and memory in a rat model of paradoxical sleep deprivation.

    Science.gov (United States)

    Hu, Yuan; Liu, Ming; Liu, Ping; Yan, Juan-Juan; Liu, Ming-Yue; Zhang, Gang-Qiang; Zhou, Xiao-Jiang; Yu, Bing-Ying

    2013-04-01

    The present study aimed to evaluate the effect of kai xin san (KXS, at doses of 500, 250, and 125 mg/kg body weight per day), a well-known traditional Chinese medicine, on learning and memory in paradoxical sleep deprivation (PSD)-induced cognition deficit rats. Two behavior tests (the Open Field test and the Morris water maze task) were used for testing the effects of KXS on a PSD-induced learning and memory deficit model. Furthermore, its effect on the glutamic acid (GLU) and γ-amino-butyric acid (GABA) levels in the brain tissue, brain-derived neurotrophic factor (BDNF), cyclic AMP response element binding protein (CREB), and phosphorylated-CREB (p-CREB) expression in the hippocampus was also tested. KXS exerted the greatest cognition against the 48 h PSD-induced cognitive deficit and these effects may be mediated by decreasing the GLU and GABA levels and increasing the levels of BDNF, CREB, and p-CREB. This study indicates that the effect of KXS on learning and memory in a rat model of PSD could be associated with the modulation of neurotransmitter levels and the expression of some genes in the brain that contribute to memory functions.

  6. Suan Zao Ren Tang in Combination with Zhi Zi Chi Tang as a Treatment Protocol for Insomniacs with Anxiety: A Randomized Parallel-Controlled Trial

    Science.gov (United States)

    Hu, Lin-lin; Zhang, Xin; Liu, Wen-juan; Li, Mei; Zhang, Yong-hua

    2015-01-01

    Insomnia is a serious worldwide health problem that is often comorbid with anxiety. The purpose of the present study was to evaluate the efficacy of a Chinese formula containing Suan Zao Ren Tang (SZRT) and Zhi Zi Chi Tang (ZZCT; SZR-ZZC) for improving sleep quality and anxiety states with four indices of Polysomnography (PSG), the Insomnia Severity Index (ISI), the Pittsburgh Sleep Quality Index (PSQI), and the Self Rating Anxiety Scale (SAS). Methods. A randomized, parallel-controlled trial compared SZR-ZZC to lorazepam tablet in insomniacs with anxiety. Patients were randomized to the SZR-ZZC treatment group (n = 60) and the lorazepam tablet treatment group (n = 59). Results. SZR-ZZC significantly improved scores on all four treatment indices. Compared with lorazepam, treatment with SZR-ZZC resulted in a significant reduction in the ISI (P = 0.029), the PSQI (P = 0.017), and wake after sleep onset (WASO; P = 0.008) scores and improved sleep architecture (P = 0.000–0.003) after a 4-week treatment period. Only one subject in the SZR-ZZC group experienced adverse side effects. Conclusion. Treatment with SZR-ZZC for 4 weeks appears to be a relatively safe and effective complementary therapeutic option when aiming to improve sleep quality and anxiety in insomniacs with anxiety. PMID:25793006

  7. Suan Zao Ren Tang in Combination with Zhi Zi Chi Tang as a Treatment Protocol for Insomniacs with Anxiety: A Randomized Parallel-Controlled Trial

    Directory of Open Access Journals (Sweden)

    Lin-lin Hu

    2015-01-01

    Full Text Available Insomnia is a serious worldwide health problem that is often comorbid with anxiety. The purpose of the present study was to evaluate the efficacy of a Chinese formula containing Suan Zao Ren Tang (SZRT and Zhi Zi Chi Tang (ZZCT; SZR-ZZC for improving sleep quality and anxiety states with four indices of Polysomnography (PSG, the Insomnia Severity Index (ISI, the Pittsburgh Sleep Quality Index (PSQI, and the Self Rating Anxiety Scale (SAS. Methods. A randomized, parallel-controlled trial compared SZR-ZZC to lorazepam tablet in insomniacs with anxiety. Patients were randomized to the SZR-ZZC treatment group (n=60 and the lorazepam tablet treatment group (n=59. Results. SZR-ZZC significantly improved scores on all four treatment indices. Compared with lorazepam, treatment with SZR-ZZC resulted in a significant reduction in the ISI (P=0.029, the PSQI (P=0.017, and wake after sleep onset (WASO; P=0.008 scores and improved sleep architecture (P=0.000–0.003 after a 4-week treatment period. Only one subject in the SZR-ZZC group experienced adverse side effects. Conclusion. Treatment with SZR-ZZC for 4 weeks appears to be a relatively safe and effective complementary therapeutic option when aiming to improve sleep quality and anxiety in insomniacs with anxiety.

  8. Molecular diversity analysis of Tetradium ruticarpum (WuZhuYu) in China based on inter-primer binding site (iPBS) markers and inter-simple sequence repeat (ISSR) markers.

    Science.gov (United States)

    Xu, Jing-Yuan; Zhu, Yan; Yi, Ze; Wu, Gang; Xie, Guo-Yong; Qin, Min-Jian

    2018-01-01

    "Wu zhu yu", which is obtained from the dried unripe fruits of Tetradium ruticarpum (A. Jussieu) T. G. Hartley, has been used as a traditional Chinese medicine for treatment of headaches, abdominal colic, and hypertension for thousands of years. The present study was designed to assess the molecular genetic diversity among 25 collected accessions of T. ruticarpum (Wu zhu yu in Chinese) from different areas of China, based on inter-primer binding site (iPBS) markers and inter-simple sequence repeat (ISSR) markers. Thirteen ISSR primers generated 151 amplification bands, of which 130 were polymorphic. Out of 165 bands that were amplified using 10 iPBS primers, 152 were polymorphic. The iPBS markers displayed a higher proportion of polymorphic loci (PPL = 92.5%) than the ISSR markers (PPL = 84.9%). The results showed that T. ruticarpum possessed high loci polymorphism and genetic differentiation occurred in this plant. The combined data of iPBS and ISSR markers scored on 25 accessions produced five clusters that approximately matched the geographic distribution of the species. The results indicated that both iPBS and ISSR markers were reliable and effective tools for analyzing the genetic diversity in T. ruticarpum. Copyright © 2018 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

  9. Clinical implication of long noncoding RNA 91H expression profile in osteosarcoma patients

    Directory of Open Access Journals (Sweden)

    Xia WK

    2016-07-01

    Full Text Available Wen-Kai Xia,1 Qing-Feng Lin,2 Dong Shen,2 Zhi-Li Liu,2 Jun Su,2 Wei-Dong Mao2 1Department of Nephrology, 2Department of Oncology, The Affiliated Jiangyin Hospital, School of Medicine, Southeast University, Jiangyin, Jiangsu, People’s Republic of China Abstract: Long noncoding RNAs have been documented as having widespread roles in carcinogenesis and cancer progression. However, roles of long noncoding RNAs in osteosarcoma remain unclear. This study is to investigate the clinical relevance and biological functions of long noncoding RNA 91H in osteosarcoma. Herein, we confirmed that 91H expression was notably increased in osteosarcoma patients and cell lines compared to healthy controls and normal human bone cell lines. High expression of 91H was significantly correlated with advanced clinical stage, chemotherapy after surgery, and tumor size >5 cm. Furthermore, 91H was an independent prognostic factor for overall survival in osteosarcoma patients after treatments. Additionally, the knockdown of 91H expression inhibited osteosarcoma cells’ proliferation and promoted their apoptosis in vitro. In summary, these findings indicate that 91H may be a novel biomarker for risk prognostication and also provide a clue to the molecular etiology of osteosarcoma. Keywords: long noncoding RNA, 91H, osteosarcoma, survival

  10. Environmental Violence in Minamata: Responsibility, Resistance, and Religiosity in the Case of Ogata Masato and Hongan no Kai

    Directory of Open Access Journals (Sweden)

    Yuki Miyamoto

    2018-05-01

    Full Text Available The small town of Minamata is infamous for the industrial disease named after the city. This disease resulted from having ingested methyl mercury, a substance released for more than three decades by a factory owned by the Chisso Corporation. Upon entering the human body, mercury affects the nervous system, resulting in paralysis, and often leading to a slow death. Examining how such violence was inflicted on human beings and on the environment involves a complex array of economic, environmental, and sociocultural issues, all revolving around the notions of justice and responsibility. This article analyzes the local residents’ responses to the irreparable damage done to them, focusing in particular on the thoughts and actions put forward by Ogata Masato and a group called Hongan no kai, who chose to carve bodhisattva statues. Investigating the victims’ religiosity, the author argues that the praxis put forward by the Minamata people resonates with the perspective articulated by Italian philosopher Giorgio Agamben. After having witnessed how justice had been exhausted and their case had been lost in the Japanese legal system, the victims showed their resilience in coming up with original responses, which also offer valuable insight into current discussions centered on environmental ethics.

  11. Cone-beam computed tomography study of the root and canal morphology of mandibular permanent anterior teeth in a Chongqing population [Corrigendum

    Directory of Open Access Journals (Sweden)

    Yang ZY

    2016-03-01

    Full Text Available Zhengyan Yang, Keke Lu, Fei Wang, Yueheng Li, Zhi ZhouDepartment of Preventive Dentistry, The College of Stomatology, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, People’s Republic of ChinaOn page 19, the author’s names were listed incorrectly as Yang Zhengyan, Lu Keke, Wang Fei, Li Yueheng, Zhou Zhi.The correct names are Zhengyan Yang, Keke Lu, Fei Wang, Yueheng Li, Zhi Zhou.View the original paper here.

  12. Minimal tool set for a prokaryotic circadian clock.

    Science.gov (United States)

    Schmelling, Nicolas M; Lehmann, Robert; Chaudhury, Paushali; Beck, Christian; Albers, Sonja-Verena; Axmann, Ilka M; Wiegard, Anika

    2017-07-21

    Circadian clocks are found in organisms of almost all domains including photosynthetic Cyanobacteria, whereby large diversity exists within the protein components involved. In the model cyanobacterium Synechococcus elongatus PCC 7942 circadian rhythms are driven by a unique KaiABC protein clock, which is embedded in a network of input and output factors. Homologous proteins to the KaiABC clock have been observed in Bacteria and Archaea, where evidence for circadian behavior in these domains is accumulating. However, interaction and function of non-cyanobacterial Kai-proteins as well as homologous input and output components remain mainly unclear. Using a universal BLAST analyses, we identified putative KaiC-based timing systems in organisms outside as well as variations within Cyanobacteria. A systematic analyses of publicly available microarray data elucidated interesting variations in circadian gene expression between different cyanobacterial strains, which might be correlated to the diversity of genome encoded clock components. Based on statistical analyses of co-occurrences of the clock components homologous to Synechococcus elongatus PCC 7942, we propose putative networks of reduced and fully functional clock systems. Further, we studied KaiC sequence conservation to determine functionally important regions of diverged KaiC homologs. Biochemical characterization of exemplary cyanobacterial KaiC proteins as well as homologs from two thermophilic Archaea demonstrated that kinase activity is always present. However, a KaiA-mediated phosphorylation is only detectable in KaiC1 orthologs. Our analysis of 11,264 genomes clearly demonstrates that components of the Synechococcus elongatus PCC 7942 circadian clock are present in Bacteria and Archaea. However, all components are less abundant in other organisms than Cyanobacteria and KaiA, Pex, LdpA, and CdpA are only present in the latter. Thus, only reduced KaiBC-based or even simpler, solely KaiC-based timing systems

  13. A case of 18p deletion syndrome after blepharoplasty

    Directory of Open Access Journals (Sweden)

    Xu LJ

    2017-01-01

    Full Text Available Li-juan Xu,1 Lv-xian Wu,2 Qing Yuan,3 Zhi-gang Lv,1 Xue-yan Jiang2 1Department of Opthalmology, 2Department of Pediatrics, 3Department of Clinical Laboratory, Jinhua Central Hospital, Jinhua, Zhejiang, People’s Republic of China Objective: The deletion of the short arm of chromosome 18 is thought to be one of the rare chromosomal aberrations. Here, we report a case to review this disease.Case report: The proband is a five-and-a-half-year-old girl who has had phenotypes manifested mainly by ptosis, broad face, broad neck with low posterior hairline, mental retardation, short stature, and other malformations. Chromosomal analysis for her mother showed a normal karyotype. Her father and younger brother were phenotypically normal.Result: Phenotypical features were quite similar throughout other cases and in accordance with the usual phenotype of del(18p suggested within the same cases and among the del(18p cases described. She underwent blepharoplasty, which improved her appearance.Conclusion: 18p deletion syndrome is diagnosed by gene analysis. Plastic surgeries for improving the appearance might be an option for these patients. Keywords: chromosome, deletion, blepharoplasty

  14. Adaptors and Innovators: A Description and Measure

    Science.gov (United States)

    Kirton, Michael

    1976-01-01

    Describes development of the Kirton Adaption Innovation Inventory (KAI) for rating respondents on a continuum of adaptiveness-innovativeness, discusses tests of the validity and utility of the KAI model, and evaluates the KAI model's characteristics. For availability see EA 507 670. (Author/JG)

  15. From the Bright Future of the Nation to the Dark Future of Mankind: Jókai and Karinthy in Hungarian Utopian Tradition

    Directory of Open Access Journals (Sweden)

    Zsolt Czigányik

    2016-01-01

    Full Text Available After defining utopianism Czigányik gives a brief introduction to Hungarian utopian literature. While he discusses Tariménes utazása [‘The Voyage of Tariménes’], written by György Bessenyei in 1804, the utopian scenes of Imre Madách’s Az ember tragédiája [‘The Tragedy of Man’, 1862] and Frigyes Karinthy’s short utopian piece, Utazás Faremidoba [‘Voyage to Faremido’, 1916], the bulk of the paper deals with Mór Jókai’s monumental novel, A jövő század regénye, [‘The Novel of the Century to Come’, 1872]. Jókai, who had taken an active part in the 1848 uprising, depicts in this novel a future world of an imaginary twentieth century, where Hungary has primacy within the Habsburg empire (with the emperor king being Árpád Habsburg and the invention of the airplane (by a Hungarian brings lasting peace, stability and prosperity to the world. Besides introducing the Hungarian utopian tradition, the paper will reflect upon the role of individuals in imagined societies and how an agency-centered narrative overwrites the essentially structuralist view of history, that usually permeates utopias.

  16. Accumulation of Arsenic Speciation and In Vivo Toxicity Following Oral Administration of a Chinese Patent Medicine Xiao-Er-Zhi-Bao-Wan in Rats

    Directory of Open Access Journals (Sweden)

    Jiaoyang Luo

    2017-07-01

    Full Text Available Realgar-containing traditional Chinese medicines such as Xiao-Er-Zhi-Bao-Wan (XEZBW, have been widely used for thousands of years. However, events associated with arsenic-induced ailments have increasingly become a public concern. To address the toxicity of XEZBW, we studied the histopathology and blood biochemistry of rats exposed to XEZBW using technology like high-performance liquid chromatography-inductively coupled mass spectrometry to determine arsenic speciation. Our results demonstrated that dimethylarsinic acid (DMA increased from 18.57 ± 7.45 to 22.74 ± 7.45 ng/g in rat kidney after oral administration for 7 and 14 days, which was 10-fold higher than the levels observed in controls. Trivalent arsenite As(III showed a large increase on day 7 (26.99 ± 1.98 ng/g, followed by a slight decrease on day 14 (13.67 ± 6.48 ng/g. Total arsenic levels on day 7 (185.52 ± 24.56 ng/g and day 14 (198.57 ± 26.26 ng/g were nearly twofold higher than that in the control group (92.77 ± 14.98 ng/g. Histopathological analysis showed mild injury in the liver and kidney of rats subjected to oral administration of realgar for 14 days. As in the XEZBW groups, a mild injury in these organs was observed after administration for 14 days. This study inferred that the toxicity of arsenic was concentration- and time-dependent. The accumulation of DMA, a byproduct of choline metabolism, was responsible for inducing higher toxicity. Therefore, we concluded that measuring the levels of DMA, instead of total arsenic, might be more suitable for evaluating the toxicity of realgar-containing traditional Chinese medicines.

  17. Study of Cu-doping effects on magnetic properties of Fe-doped ZnO ...

    Indian Academy of Sciences (India)

    Administrator

    To take into account the random distribution of ... and spin–orbit interaction were taken into account. .... Lee H J, Jeong S-Y, Ryong Cho C and Hong Park C 2002 Appl. Phys. Lett. ... Zhang Hua-Wei, Wei Zhi-Ren, Li Zhi-Qiang and Dong Guo-Yi.

  18. The complete mitochondrial genome and its remarkable secondary structure for a stonefly Acroneuria hainana Wu (Insecta: Plecoptera, Perlidae).

    Science.gov (United States)

    Huang, Mingchao; Wang, Yuyu; Liu, Xingyue; Li, Weihai; Kang, Zehui; Wang, Kai; Li, Xuankun; Yang, Ding

    2015-02-15

    The Plecoptera (stoneflies) is a hemimetabolous order of insects, whose larvae are usually used as indicators for fresh water biomonitoring. Herein, we describe the complete mitochondrial (mt) genome of a stonefly species, namely Acroneuria hainana Wu belonging to the family Perlidae. This mt genome contains 13 PCGs, 22 tRNA-coding genes and 2 rRNA-coding genes that are conserved in most insect mt genomes, and it also has the identical gene order with the insect ancestral gene order. However, there are three special initiation codons of ND1, ND5 and COI in PCGs: TTG, GTG and CGA, coding for L, V and R, respectively. Additionally, the 899-bp control region, with 73.30% A+T content, has two long repeated sequences which are found at the 3'-end closing to the tRNA(Ile) gene. Both of them can be folded into a stem-loop structure, whose adjacent upstream and downstream sequences can be also folded into stem-loop structures. It is presumed that the four special structures in series could be associated with the D-loop replication. It might be able to adjust the replication speed of two replicate directions. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. FORTRAN Code for Glandular Dose Calculation in Mammography Using Sobol-Wu Parameters

    Directory of Open Access Journals (Sweden)

    Mowlavi A A

    2007-07-01

    Full Text Available Background: Accurate computation of the radiation dose to the breast is essential to mammography. Various the thicknesses of breast, the composition of the breast tissue and other variables affect the optimal breast dose. Furthermore, the glandular fraction, which refers to the composition of the breasts, as partitioned between radiation-sensitive glandular tissue and the adipose tissue, also has an effect on this calculation. Fatty or fibrous breasts would have a lower value for the glandular fraction than dense breasts. Breast tissue composed of half glandular and half adipose tissue would have a glandular fraction in between that of fatty and dense breasts. Therefore, the use of a computational code for average glandular dose calculation in mammography is a more effective means of estimating the dose of radiation, and is accurate and fast. Methods: In the present work, the Sobol-Wu beam quality parameters are used to write a FORTRAN code for glandular dose calculation in molybdenum anode-molybdenum filter (Mo-Mo, molybdenum anode-rhodium filter (Mo-Rh and rhodium anode-rhodium filter (Rh-Rh target-filter combinations in mammograms. The input parameters of code are: tube voltage in kV, half-value layer (HVL of the incident x-ray spectrum in mm, breast thickness in cm (d, and glandular tissue fraction (g. Results: The average glandular dose (AGD variation against the voltage of the mammogram X-ray tube for d = 4 cm, HVL = 0.34 mm Al and g=0.5 for the three filter-target combinations, as well as its variation against the glandular fraction of breast tissue for kV=25, HVL=0.34, and d=4 cm has been calculated. The results related to the average glandular absorbed dose variation against HVL for kV = 28, d=4 cm and g= 0.6 are also presented. The results of this code are in good agreement with those previously reported in the literature. Conclusion: The code developed in this study calculates the glandular dose quickly, and it is complete and

  20. Discovery of estrogen receptor α modulators from natural compounds in Si-Wu-Tang series decoctions using estrogen-responsive MCF-7 breast cancer cells.

    Science.gov (United States)

    Liu, Li; Ma, Hongyue; Tang, Yuping; Chen, Wenxing; Lu, Yin; Guo, Jianming; Duan, Jin-Ao

    2012-01-01

    The binding between the estrogen receptor α (ER-α) and a variety of compounds in traditional Chinese formulae, Si-Wu-Tang (SWT) series decoctions, was studied using a stably-transfected human breast cancer cell line (MVLN). In 38 compounds tested from SWT series decoctions, the estrogen-like activity of 22 compounds was above 60% in 20 μg mL(-1). Furthermore, theoretical affinity of these compounds was certificated using the functional virtual screen of ER-α modulators by FlexX-Pharm. The accuracy of functional virtual screening of ER-α modulators could reach to 77.27%. The results showed that some compounds, such as organic acids and flavones in SWT series decoctions could be used as selective estrogen receptor modulators (SERMs) and could be selected for further development as potential agents for estrogen related diseases. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. Lung cancer with concurrent EGFR mutation and ROS1 rearrangement: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Zhu YC

    2016-07-01

    Full Text Available You-cai Zhu,1,2,* Chun-wei Xu,3,* Xiao-qian Ye,4 Man-xiang Yin,4 Jin-xian Zhang,2 Kai-qi Du,2 Zhi-hao Zhang,2 Jian Hu1 1Department of Thoracic Surgery, The First Affiliated Hospital of Medical School of Zhejiang University, Hangzhou, 2Department of Thoracic Surgery, Chinese People’s Armed Police Force, Zhejiang Corps Hospital, Jiaxing, Zhejiang, 3Department of Pathology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing, 4Department of Pathology, Chinese People’s Armed Police Force, Zhejiang Corps Hospital, Jiaxing, Zhejiang, People’s Republic of China *These authors contributed equally to this work Abstract: ROS1 rearrangement has recently emerged as a new molecular subtype in non-small cell lung cancer, and is predominantly found in lung adenocarcinomas compared with other oncogenes such as EGFR, KRAS, or ALK. Patients who have both mutations are extremely rare. Here we report a 50-year-old female diagnosed with adenocarcinoma with sarcomatoid differentiation, who was shown to have EGFR and ROS1 mutations. The patient was treated surgically and received three cycles of adjuvant postoperative chemotherapy. In addition, we reviewed the previously reported cases and related literature. This presentation will provide further understanding of the underlying molecular biology and optimal treatment for non-small cell lung cancer patients with more than one driver mutation. Keywords: non-small cell lung cancer, EGFR gene mutation, ROS1 fusion gene

  2. Preconditioning with Gua Lou Gui Zhi decoction enhances H2O2-induced Nrf2/HO-1 activation in PC12 cells

    Science.gov (United States)

    MAO, JINGJIE; LI, ZUANFANG; LIN, RUHUI; ZHU, XIAOQIN; LIN, JIUMAO; PENG, JUN; CHEN, LIDIAN

    2015-01-01

    Spasticity is common in various central neurological conditions, including after a stroke. Such spasticity may cause additional problems, and often becomes a primary concern for afflicted individuals. A number of studies have identified nuclear factor (erythroid-derived 2)-like 2 (Nrf2) as a key regulator in the adaptive survival response to oxidative stress. Elevated expression of Nrf2, combined with heme oxygenase 1 (HO-1) resistance, in the central nervous system is known to elicit key internal and external oxidation protection. Gua Lou Gui Zhi decoction (GLGZD) is a popular traditional Chinese formula with a long history of clinical use in China for the treatment of muscular spasticity following a stroke, epilepsy or a spinal cord injury. However, the mechanism underlying the efficacy of the medicine remains unclear. In the present study, the antioxidative effects of GLGZD were evaluated and the underlying molecular mechanisms were investigated, using hydrogen peroxide (H2O2)-induced rat pheochromocytoma cells (PC12 cells) as an in vitro oxidative stress model of neural cells. Upon application of different concentrations of GLGZD, a 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium bromide (MTT) assay and ATP measurement were conducted to assess the impact on PC12 cell proliferation. In addition, inverted microscopy observations, and the MTT and ATP assessments, revealed that GLGZD attenuated H2O2-induced oxidative damage and signaling repression in PC12 cells. Furthermore, the mRNA and protein expression levels of Nrf2 and HO-1, which are associated with oxidative stress, were analyzed using reverse transcription quantitative polymerase chain reaction (PCR) and confocal microscopy. Confocal microscopy observations, as well as the quantitative PCR assay, revealed that GLGZD exerted a neuroprotective function against H2O2-induced oxidative damage in PC12 cells. Therefore, the results demonstrated that GLGZD protected PC12 cells injured by H2O2, which may be

  3. An allele of the crm gene blocks cyanobacterial circadian rhythms.

    Science.gov (United States)

    Boyd, Joseph S; Bordowitz, Juliana R; Bree, Anna C; Golden, Susan S

    2013-08-20

    The SasA-RpaA two-component system constitutes a key output pathway of the cyanobacterial Kai circadian oscillator. To date, rhythm of phycobilisome associated (rpaA) is the only gene other than kaiA, kaiB, and kaiC, which encode the oscillator itself, whose mutation causes completely arrhythmic gene expression. Here we report a unique transposon insertion allele in a small ORF located immediately upstream of rpaA in Synechococcus elongatus PCC 7942 termed crm (for circadian rhythmicity modulator), which results in arrhythmic promoter activity but does not affect steady-state levels of RpaA. The crm ORF complements the defect when expressed in trans, but only if it can be translated, suggesting that crm encodes a small protein. The crm1 insertion allele phenotypes are distinct from those of an rpaA null; crm1 mutants are able to grow in a light:dark cycle and have no detectable oscillations of KaiC phosphorylation, whereas low-amplitude KaiC phosphorylation rhythms persist in the absence of RpaA. Levels of phosphorylated RpaA in vivo measured over time are significantly altered compared with WT in the crm1 mutant as well as in the absence of KaiC. Taken together, these results are consistent with the hypothesis that the Crm polypeptide modulates a circadian-specific activity of RpaA.

  4. Wu-Tou Decoction Inhibits Chronic Inflammatory Pain in Mice: Participation of TRPV1 and TRPA1 Ion Channels

    Directory of Open Access Journals (Sweden)

    Chao Wang

    2015-01-01

    Full Text Available Wu-tou decoction (WTD is a classic traditional Chinese medicine formula and has been used effectively to treat joint diseases clinically. Previous reports indicated that WTD possesses anti-inflammatory activity; however, its actions on pain have not been clarified. Here, we investigated the antinociceptive activity of WTD in CFA-induced mice, and its possible mechanism of the action associated with transient receptor potential (TRP ion channels was also explored. Our results showed that 1.58, 3.15, and 6.30 g/kg WTD significantly attenuated mechanical, cold, and heat hypersensitivities. Moreover, WTD effectively inhibited spontaneous nociceptive responses to intraplantar injections of capsaicin and cinnamaldehyde, respectively. WTD also effectively suppressed jumping and wet-dog-shake behaviors to intraperitoneal injection of icilin. Additionally, WTD significantly reduced protein expression of TRPV1 and TRPA1 in dorsal root ganglia and skins of injured paw. Collectively, our data demonstrate firstly that WTD exerts antinociceptive activity in inflammatory conditions by attenuating mechanical, cold, and heat hypersensitivities. This antinociceptive effect may result in part from inhibiting the activities of TRPV1, TRPA1, and TRPM8, and the suppression of TRPV1 and TRPA1 protein by WTD was also highly effective. These findings suggest that WTD might be an attractive and suitable therapeutic agent for the management of chronic inflammatory pain.

  5. Relationships among Constitution, Stress, and Discomfort in the First Trimester

    Directory of Open Access Journals (Sweden)

    Hsiao-Ling Wang

    2012-01-01

    trimester of pregnancy. We adopted a descriptive and correlational research design and collected data from 261 pregnant women during their first trimester in southern Taiwan using structured questionnaires. Results showed that (1 stress was significantly and positively correlated with Yang-Xu, Yin-Xu, and Tan-Shi-Yu-Zhi constitutions, respectively; (2 Yin-Xu and Tan-Shi-Yu-Zhi constitutions had significant correlations with all symptoms of discomfort, while Yang-Xu had significant correlations with all symptoms of discomfort except for “running nose”; (3 Tan-Shi-Yu-Zhi constitution and stress were two indicators for “fatigue”; Tan-Shi-Yu-Zhi was the indicator for “nausea”; Yang-Xu and Yin-Xu were indicators for “frequent urination.” Our findings also indicate that stress level affects constitutional changes and that stress and constitutional change affect the incidence of discomfort. This research can help healthcare professionals observe these discomforts and provide individualized care for pregnant women, to nurture pregnant women into neutral-type constitution, minimize their levels of discomfort, and promote the health of the fetus and the mother.

  6. Si-Wu-tang extract stimulates bone formation through PI3K/Akt/NF-κB signaling pathways in osteoblasts.

    Science.gov (United States)

    Wu, Chi-Ming; Chen, Po-Chun; Li, Te-Mao; Fong, Yi-Chin; Tang, Chih-Hsin

    2013-10-24

    Si-Wu-Tang (SWT), a Traditional Chinese Medicine (TCM) formula, is widely used for the treatment of gynopathies diseases such as menstrual discomfort, climacteric syndrome, dysmenorrhea, and other estrogen-related diseases. Recent studies have shown that SWT can treat primary dysmenorrhea, have anti-pruritic anti-inflammatory effects, and protect against radiation-induced bone marrow damage in an animal model. It has been reported that anti-inflammatory and anti-oxidant agents have the potential to treat osteoporosis by increasing bone formation and/or suppressing bone resorption. However, the effect of SWT on bone cell function has not yet been reported. Alkaline phosphatase (ALP), bone morphogenetic proteins (BMP)-2, and osteopontin (OPN) mRNA expression was analyzed by qPCR. The mechanism of action of SWT extract was investigated using western blotting. The in vivo anti-osteoporotic effect of SWT extract was assessed in ovariectomized mice. Here, we report that SWT increases ALP, BMP-2, and OPN expression as well as bone mineralization. In addition, we show that the PI3K, Akt, and NF-κB signaling pathways may be involved in the SWT-mediated increase in gene expression and bone mineralization. Notably, treatment of mice with SWT extract prevented bone loss induced by ovariectomy in vivo. SWT may be used to stimulate bone formation for the treatment of osteoporosis.

  7. [Textual research on Guang dong xin yu (New Sayings of Guangdong) quoted in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica].

    Science.gov (United States)

    Zhang, Ruixian; Zhang, Wei; Li, Jian; Liang, Fei

    2014-05-01

    Altogether 15 terms for Guang dong xin yu (New Sayings of Guangdong) were used in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica), including Yue yu (Cantonese sayings), Chong yu (Sayings from Insect Drug), Jie yu (Sayings from Crustacean Drug), Xin yu (New Sayings), Yue hai xiang yu (Fragrant Sayings from Cantonese Region), Yue zhi mu yu (Sayings from Plants in Cantonese Annals), Guang dong suo yu (Trivial Sayings from Guangdong), Yue shan lu (Records of Cantonese Mountains), Yue lu (Cantonese Records), Jiao guang lu (Joint Guangdong Records), Yue cao zhi (Records of Cantonese Grasses), Guang guo lu (Records of Guangdong Fruits), Nan yue suo ji (Trivial Records of Southern Canton), Guang zhi (Guangdong Records), Yue zhi (Cantonese Records) etc. dealing with 57 sorts of drugs (with individual overlapping ones), the author of Xin yu was Qu Dajun, a surviving fogy of the Ming Dynasty actively involved in the activities to restore the old dynasty and resist the Qing Dynasty, and was persecuted in the literary inquisition in which his works were burnt so that Zhao Xuemin, when quoting his texts, had to go in a roundabout way.

  8. Lipid-lowering and antioxidant activities of Jiang-Zhi-Ning in Traditional Chinese Medicine.

    Science.gov (United States)

    Chen, Jianxin; Zhao, Huihui; Yang, Ying; Liu, Bing; Ni, Jian; Wang, Wei

    2011-04-12

    Jiang-Zhi-Ning (JZN) is composed of four Chinese herbs, i.e., Fleeceflower Root, Fructus Crataegi, Folium Nelumbinis and Semen Cassiae. It was used to strengthen blood circulation of coronary artery, arrhythmia and hyperlipidemia. The main objective of this paper is to evaluate lipid-lowering and antioxidant activities of extract and effective fraction of JZN by using in vitro experiments on hyperlipidemic rats. Moreover, in vivo experiments on cells were performed to investigate lipid-lowering and antioxidant activities of effective fraction and active constituents of JZN. Wistar rats with high fat diet-induced hyperlipidemia were used as in vitro models to study biological effects of lipid-lowering and antioxidant activities of extract and effective fraction of JZN. Serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), Coronary Index and Atherogenic Index were investigated to evaluate lipid-lowering effects of extract and effective fraction of JZN. Serum total nitric oxide synthase (NOS), nitric oxide (NO), endothelin-1 (ET-1), malondialdehyde (MDA), superoxide dismutase (SOD) and total antioxidant capacity (T-AOC) were detected to measure antioxidant effects of extract and effective fraction of JZN. Furthermore, oxidized low-density lipoprotein (Ox-LDL) injured human umbilical vein endothelial cell (HUVEC) model was employed as in vivo experiment to study lipid-lowering and antioxidant effects of effective fraction and active constituents of JZN. NO, ET-1, MDA SOD and T-AOC in HUVECs or culture media were investigated to evaluate antioxidant activity of effective fraction and active constituents of JZN. Using human hepatoma cell line Bel-7402, reverse transcription polymerase chain reaction (RT-PCR) technology was performed to investigate cholesterol metabolism effects of effective fraction and active constituents of JZN. Expressions of low density lipoprotein receptor (LDL

  9. A Modified Chinese Herbal Decoction (Kai-Xin-San Promotes NGF-Induced Neuronal Differentiation in PC12 Cells via Up-Regulating Trk A Signaling

    Directory of Open Access Journals (Sweden)

    Lu Yan

    2017-12-01

    Full Text Available Kai-Xin-San (KXS, a Chinese herbal decoction, has been applied to medical care of depression for thousands of years. It is composed of two functional paired-herbs: Ginseng Radix et Rhizoma (GR-Polygalae Radix (PR and Acori Tatarinowii Rhizoma (ATR-Poria (PO. The compatibility of the paired-herbs has been frequently changed to meet the criteria of syndrome differentiation and treatment variation. Currently, a modified KXS (namely KXS2012 was prepared by optimizing the combinations of GR-PR and ATR-PO: the new herbal formula was shown to be very effective in animal studies. However, the cellular mechanism of KXS2012 against depression has not been fully investigated. Here, the study on KXS2012-induced neuronal differentiation in cultured PC12 cells was analyzed. In PC12 cultures, single application of KXS2012 showed no effect on the neuronal differentiation, but which showed robust effects in potentiating nerve growth factor (NGF-induced neurite outgrowth and neurofilament expression. The potentiating effect of KXS2012 was mediated through NGF receptor, tropomyosin receptor kinase (Trk A: because the receptor expression and activity was markedly up-regulated in the presence of KXS2012, and the potentiating effect was blocked by k252a, an inhibitor of Trk A. Our current results in cell cultures fully support the therapeutic efficacy of KXS2012 against depression.

  10. Un imaginaire dévoilé/déphasé. Stratégies narratives et mémoire culturelle dans le roman 54 des Wu Ming

    Directory of Open Access Journals (Sweden)

    Matteo Martelli

    2015-02-01

    Full Text Available This essay analyses the narrative strategies through which cultural memory is portrayed in 54, a novel in which Wu Ming (a collective of four Italian fiction writers suggests a literary mapping of the Fifties. This is obtained by a recovery of a shared imaginary tradition which is close to the reader, mixing fictional and historical characters, films, books, different genres of popular literature. Nevertheless, the rewriting of these imaginary traditions involves their displacement, a presentation which is constantly created from an unusual point of view. Thus, shifting the image of what is already known, the text inquires into several modalities of a questioning about cultural memory and its redefinition in relation to contemporary culture. By focusing on these elements, this study proposes an analysis which starts from the construction of the characters, the role of suspense and the adoption of multiple traditions of novel writing.

  11. Kenya AIDS Indicator Surveys 2007 and 2012: implications for public health policies for HIV prevention and treatment.

    Science.gov (United States)

    Maina, William K; Kim, Andrea A; Rutherford, George W; Harper, Malayah; K'Oyugi, Boniface O; Sharif, Shahnaaz; Kichamu, George; Muraguri, Nicholas M; Akhwale, Willis; De Cock, Kevin M

    2014-05-01

    AIDS Indicator Surveys are standardized surveillance tools used by countries with generalized HIV epidemics to provide, in a timely fashion, indicators for effective monitoring of HIV. Such data should guide responses to the HIV epidemic, meet program reporting requirements, and ensure comparability of findings across countries and over time. Kenya has conducted 2 AIDS Indicator Surveys, in 2007 (KAIS 2007) and 2012-2013 (KAIS 2012). These nationally representative surveys have provided essential epidemiologic, sociodemographic, behavioral, and biologic data on HIV and related indicators to evaluate the national HIV response and inform policies for prevention and treatment of the disease. We present a summary of findings from KAIS 2007 and KAIS 2012 and the impact that these data have had on changing HIV policies and practice.

  12. A Standardized Chinese Herbal Decoction, Kai-Xin-San, Restores Decreased Levels of Neurotransmitters and Neurotrophic Factors in the Brain of Chronic Stress-Induced Depressive Rats

    Science.gov (United States)

    Zhu, Kevin Yue; Mao, Qing-Qiu; Ip, Siu-Po; Choi, Roy Chi-Yan; Dong, Tina Ting-Xia; Lau, David Tai-Wai; Tsim, Karl Wah-Keung

    2012-01-01

    Kai-xin-san (KXS), a Chinese herbal decoction being prescribed by Sun Simiao in Beiji Qianjin Yaofang about 1400 years ago, contains Ginseng Radix et Rhizoma, Polygalae Radix, Acori tatarinowii Rhizoma, and Poria. KXS has been used to treat stress-related psychiatric disease with the symptoms of depression and forgetfulness in ancient China until today. However, the mechanism of its antidepression action is still unknown. Here, the chronic mild-stress-(CMS-) induced depressive rats were applied in exploring the action mechanisms of KXS treatment. Daily intragastric administration of KXS for four weeks significantly alleviated the CMS-induced depressive symptoms displayed by enhanced sucrose consumption. In addition, the expressions of those molecular bio-markers relating to depression in rat brains were altered by the treatment of KXS. These KXS-regulated brain biomarkers included: (i) the levels of dopamine, norepinephrine, and serotonin (ii) the transcript levels of proteins relating to neurotransmitter metabolism; (iii) the transcript levels of neurotrophic factors and their receptors. The results suggested that the anti-depressant-like action of KXS might be mediated by an increase of neurotransmitters and expression of neurotrophic factors and its corresponding receptors in the brain. Thus, KXS could serve as alternative medicine, or health food supplement, for patients suffering from depression. PMID:22973399

  13. A Standardized Chinese Herbal Decoction, Kai-Xin-San, Restores Decreased Levels of Neurotransmitters and Neurotrophic Factors in the Brain of Chronic Stress-Induced Depressive Rats

    Directory of Open Access Journals (Sweden)

    Kevin Yue Zhu

    2012-01-01

    Full Text Available Kai-xin-san (KXS, a Chinese herbal decoction being prescribed by Sun Simiao in Beiji Qianjin Yaofang about 1400 years ago, contains Ginseng Radix et Rhizoma, Polygalae Radix, Acori tatarinowii Rhizoma, and Poria. KXS has been used to treat stress-related psychiatric disease with the symptoms of depression and forgetfulness in ancient China until today. However, the mechanism of its antidepression action is still unknown. Here, the chronic mild-stress-(CMS- induced depressive rats were applied in exploring the action mechanisms of KXS treatment. Daily intragastric administration of KXS for four weeks significantly alleviated the CMS-induced depressive symptoms displayed by enhanced sucrose consumption. In addition, the expressions of those molecular bio-markers relating to depression in rat brains were altered by the treatment of KXS. These KXS-regulated brain biomarkers included: (i the levels of dopamine, norepinephrine, and serotonin (ii the transcript levels of proteins relating to neurotransmitter metabolism; (iii the transcript levels of neurotrophic factors and their receptors. The results suggested that the anti-depressant-like action of KXS might be mediated by an increase of neurotransmitters and expression of neurotrophic factors and its corresponding receptors in the brain. Thus, KXS could serve as alternative medicine, or health food supplement, for patients suffering from depression.

  14. Epigenetic Machinery Regulates Alternative Splicing of Androgen Receptor (AR) Gene in Castration Resistant Prostate Cancer

    Science.gov (United States)

    2017-09-01

    resistant prostate cancer PRINCIPAL INVESTIGATOR: Zhi-Ping Liu CONTRACTING ORGANIZATION: UT Southwestern Medical Center Dallas, TX 75390 REPORT DATE...NUMBER gene in castration-resistant prostate cancer 5b. GRANT NUMBER W81XWH-16-1-0531 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Zhi-Ping Liu 5d...NOTES 14. ABSTRACT Androgen deprivation therapy (ADT) is the primary treatment for metastatic prostate cancer (PCa) since PCa depends on androgen for

  15. Stereotactic body radiation therapy for patients with recurrent pancreatic adenocarcinoma at the abdominal lymph nodes or postoperative stump including pancreatic stump and other stump

    Directory of Open Access Journals (Sweden)

    Zeng XL

    2016-06-01

    Full Text Available Xian-Liang Zeng,* Huan-Huan Wang,* Mao-Bin Meng, Zhi-Qiang Wu, Yong-Chun Song, Hong-Qing Zhuang, Dong Qian, Feng-Tong Li, Lu-Jun Zhao, Zhi-Yong Yuan, Ping Wang Department of Radiation Oncology, Tianjin’s Clinical Research Center for Cancer and Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, People’s Republic of China *These authors contributed equally to this work Background and aim: The aim of this study is to evaluate the efficacy and safety of stereotactic body radiation therapy (SBRT using CyberKnife in the treatment of patients with recurrent pancreatic adenocarcinoma at the abdominal lymph node or stump after surgery. Patients and methods: Between October 1, 2006 and May 1, 2015, patients with recurrent pancreatic adenocarcinoma at the abdominal lymph node or stump after surgery were enrolled and treated with SBRT at our hospital. The primary end point was local control rate after SBRT. Secondary end points were overall survival, time to symptom alleviation, and toxicity, assessed using the Common Terminology Criteria for Adverse Events version 4.0. Results: Twenty-four patients with 24 lesions (17 abdominal lymph nodes and seven stumps were treated with SBRT, of which five patients presented with abdominal lymph nodes and synchronous metastases in the liver and lung. The 6-, 12-, and 24-month actuarial local control rates were 95.2%, 83.8%, and 62.1%, respectively. For the entire cohort, the median overall survival from diagnosis and SBRT was 28.9 and 12.2 months, respectively. Symptom alleviation was observed in eleven of 14 patients (78.6% within a median of 8 days (range, 1–14 days after SBRT. Nine patients (37.5% experienced Common Terminology Criteria for Adverse Events version 4.0 grade 1–2 acute toxicities; one patient experienced grade 3 acute toxicity due to thrombocytopenia. Conclusion: SBRT is a safe and

  16. Inhibition of Neoplastic Transformation and Chemically-Induced Skin Hyperplasia in Mice by Traditional Chinese Medicinal Formula Si-Wu-Tang

    Directory of Open Access Journals (Sweden)

    Mandy M. Liu

    2017-03-01

    Full Text Available Exploring traditional medicines may lead to the development of low-cost and non-toxic cancer preventive agents. Si-Wu-Tang (SWT, comprising the combination of four herbs, Rehmanniae, Angelica, Chuanxiong, and Paeoniae, is one of the most popular traditional Chinese medicines for women’s diseases. In our previous studies, the antioxidant Nrf2 pathways were strongly induced by SWT in vitro and in vivo. Since Nrf2 activation has been associated with anticarcinogenic effects, the purpose of this study is to evaluate SWT’s activity of cancer prevention. In the Ames test, SWT demonstrated an antimutagenic activity against mutagenicity induced by the chemical carcinogen 7,12-dimethylbenz(aanthracene (DMBA. In JB6 P+ cells, a non-cancerous murine epidermal model for studying tumor promotion, SWT inhibited epidermal growth factor (EGF-induced neoplastic transformation. The luciferase reporter gene assays demonstrated that SWT suppressed EGF-induced AP-1 and TNF-α-induced NF-κB activation, which are essential factors involved in skin carcinogenesis. In a DMBA-induced skin hyperplasia assay in ‘Sensitivity to Carcinogenesis’ (SENCAR mice, both topical and oral SWT inhibited DMBA-induced epidermal hyperplasia, expression of the proliferation marker Proliferating cell nuclear antigen (PCNA, and H-ras mutations. These findings demonstrate, for the first time, that SWT prevents tumor promoter and chemical-induced carcinogenesis in vitro and in vivo, partly by inhibiting DNA damage and blocking the activation of AP-1 and NF-κB.

  17. Marketingo komunikacijos priemonių naudojimas šiaulių universitete vykdomų ES struktūrinių fondų projektų pavyzdžiu

    OpenAIRE

    Gyraitė, Lina; Bivainiennė, Lina

    2008-01-01

    Straipsnyje analizuojamas marketingo komunikacijos elementų taikymas Šiaulių universitete vykdomiems ES struktūrinių fondų projektams. Marketingo komunikaciją galima apibūdinti kaip būdą, kai naudojant įvairias komunikacijos priemones, pasiekiamos numatytos tikslinės auditorijos, perduodama reikalinga informacija ir taip siekiama jas paveikti. Straipsnyje teoriškai ir praktiškai analizuojamos marketingo komunikacijos Šiaulių universitete vykdomų ES struktūrinių fondų projektų pavyzdžiu. Moksl...

  18. Combination of counterpropagation artificial neural networks and antioxidant activities for comprehensive evaluation of associated-extraction efficiency of various cyclodextrins in the traditional Chinese formula Xue-Zhi-Ning.

    Science.gov (United States)

    Sun, Lili; Yang, Jianwen; Wang, Meng; Zhang, Huijie; Liu, Yanan; Ren, Xiaoliang; Qi, Aidi

    2015-11-10

    Xue-Zhi-Ning (XZN) is a widely used traditional Chinese medicine formula to treat hyperlipidemia. Recently, cyclodextrins (CDs) have been extensively used to minimize problems relative to medicine bioavailability, such as low solubility and poor stability. The objective of this study was to determine the associated-extraction efficiency of various CDs in XZN. Three various type CDs were evaluated, including native CDs (α-CD, β-CD), hydrophilic CD derivatives (HP-β-CD and Me-β-CD), and ionic CD derivatives (SBE-β-CD and CM-β-CD). An ultra high-performance liquid chromatography (UHPLC) fingerprint was applied to determine the components in CD extracts and original aqueous extract (OAE). A counterpropagation artificial neural network (CP-ANN) was used to analyze the components in different extracts and compare the selective extraction of various CDs. Extraction efficiencies of the various CDs in terms of extracted components follow the ranking, ionic CD derivatives>hydrophilic CD derivatives>native CDs>OAE. Besides, different types of CDs have their own selective extraction and ionic CD derivatives present the strongest associated-extraction efficiency. Antioxidant potentials of various extracts were evaluated by determining the inhibition of spontaneous, H2O2-induced, CCl4-induced and Fe(2+)/ascorbic acid-induced lipid peroxidation (LPO) and analyzing the scavenging capacity for DPPH and hydroxyl radicals. The order of extraction efficiencies of the various CDs relative to antioxidant activities is as follows: SBE-β-CD>CM-β-CD>HP-β-CD>Me-β-CD>β-CD>α-CD. It can be demonstrated that all of the CDs studied increase the extraction efficiency and that ionic CD derivatives (SBE-β-CD and CM-β-CD) present the highest extraction capability in terms of amount extracted and antioxidant activities of extracts. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. An application of adaption-innovation theory to bioremediation

    Energy Technology Data Exchange (ETDEWEB)

    Guerin, L.J. [World Trade Centre, Melbourne, Victoria (Australia); Guerin, T.F. [Minenco Bioremediation Services, Bundoora, Victoria (Australia)

    1995-12-31

    This paper provides a discussion of the potential application of the Kirton Adaption-Innovation Inventory (KAI) for assessing the adaptive-innovative cognitive style of individuals and organizations within the bioremediation industry. Human-resource and line managers, or other individuals responsible for staff evaluation, selection, and project planning, should consider using the KAI to assist them in selecting individuals for specific roles requiring either an innovative or adaptive style. The KAI, a measure for assessing adaption-innovation at the individual employee level, is introduced and its potential value in the bioremediation industry is discussed.

  20. Sociopato portreto vaizdavimas kinematografijoje

    OpenAIRE

    Uldukis, Vytautas

    2014-01-01

    Diplominiame darbe „Sociopato portreto vaizdavimas kinematografijoje“ nagrinėjama kaip ir kokiomis priemonėmis kino filmuose vaizduojami sociopatijos paveikti asmenys. Šis reiškinys psichologiškai dar nėra visiškai išnagrinėtas, todėl yra labai sunku visuomenėje nustatyti sociopatus. Pasireiškia tik atskiri atvejai kai jie yra demaskuojami dėl to, kad nusižengė įstatymams ir nepakluso teisėtvarkai. Nemažai įvairaus laikotarpio filmų sukuriama remiantis sociopatijos reiškiniu, kuriuose sukuria...

  1. A Cross-Validation Study of the Kirton Adaption-Innovation Inventory in Three Research and Development Organizations.

    Science.gov (United States)

    Keller, Robert T.; Holland, Winford E.

    1979-01-01

    A cross-validation study of the Kirton Adaption-Innovation Inventory (KAI) was conducted with 256 professional employees from three applied research and development organizations. The KAI correlated well with both direct and indirect measures of innovativeness in all three organizations. (Author/MH)

  2. 4. VII kell 17 avatakse Haapsalu Evald Okase muuseumis rahvusvaheline klaasinäitus...

    Index Scriptorium Estoniae

    2004-01-01

    Ühtlasi lõpevad II Haapsalu klaasipäevad "Maritima". Korraldaja Kai Koppel. Klaasi puhuvad Rait Parts, Robert Tannahill Kanadast, Sun Hwan Hong Koreast, Kai Koppel. Näitusel näeb eesti klaasikunstnike Mare Saare, Ivo Lille, Rait Präätsa jt. töid

  3. The complete mitochondrial genome of the styloperlid stonefly species Styloperla spinicercia Wu (Insecta: Plecoptera) with family-level phylogenetic analyses of the Pteronarcyoidea.

    Science.gov (United States)

    Wang, Ying; Cao, Jinjun; Li, Weihai

    2017-03-13

    We present the complete mitochondrial (mt) genome sequence of the stonefly, Styloperla spinicercia Wu, 1935 (Plecoptera: Styloperlidae), the type species of the genus Styloperla and the first complete mt genome for the family Styloperlidae. The genome is circular, 16,129 base pairs long, has an A+T content of 70.7%, and contains 37 genes including the large and small ribosomal RNA (rRNA) subunits, 13 protein coding genes (PCGs), 22 tRNA genes and a large non-coding region (CR). All of the PCGs use the standard initiation codon ATN except ND1 and ND5, which start with TTG and GTG. Twelve of the PCGs stop with conventional terminal codons TAA and TAG, except ND5 which shows an incomplete terminator signal T. All tRNAs have the classic clover-leaf structures with the dihydrouridine (DHU) arm of tRNASer(AGN) forming a simple loop. Secondary structures of the two ribosomal RNAs are presented with reference to previous models. The structural elements and the variable numbers of tandem repeats are described within the control region. Phylogenetic analyses using both Bayesian (BI) and Maximum Likelihood (ML) methods support the previous hypotheses regarding family level relationships within the Pteronarcyoidea. The genetic distance calculated based on 13 PCGs and two rRNAs between Styloperla sp. and S. spinicercia is provided and interspecific divergence is discussed.

  4. Near-infrared light-triggered theranostics for tumor-specific enhanced multimodal imaging and photothermal therapy

    Directory of Open Access Journals (Sweden)

    Wu B

    2017-06-01

    Full Text Available Bo Wu,1,* Bing Wan,2,* Shu-Ting Lu,1 Kai Deng,3 Xiao-Qi Li,1 Bao-Lin Wu,1 Yu-Shuang Li,1 Ru-Fang Liao,1 Shi-Wen Huang,3 Hai-Bo Xu1,2 1Department of Radiology, Zhongnan Hospital of Wuhan University, 2Department of Radiology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, 3Department of Chemistry, Key Laboratory of Biomedical Polymers, Ministry of Education, Wuhan University, Wuhan, People’s Republic of China *These authors contributed equally to this work Abstract: The major challenge in current clinic contrast agents (CAs and chemotherapy is the poor tumor selectivity and response. Based on the self-quench property of IR820 at high concentrations, and different contrast effect ability of Gd-DOTA between inner and outer of liposome, we developed “bomb-like” light-triggered CAs (LTCAs for enhanced CT/MRI/FI multimodal imaging, which can improve the signal-to-noise ratio of tumor tissue specifically. IR820, Iohexol and Gd-chelates were firstly encapsulated into the thermal-sensitive nanocarrier with a high concentration. This will result in protection and fluorescence quenching. Then, the release of CAs was triggered by near-infrared (NIR light laser irradiation, which will lead to fluorescence and MRI activation and enable imaging of inflammation. In vitro and in vivo experiments demonstrated that LTCAs with 808 nm laser irradiation have shorter T1 relaxation time in MRI and stronger intensity in FI compared to those without irradiation. Additionally, due to the high photothermal conversion efficiency of IR820, the injection of LTCAs was demonstrated to completely inhibit C6 tumor growth in nude mice up to 17 days after NIR laser irradiation. The results indicate that the LTCAs can serve as a promising platform for NIR-activated multimodal imaging and photothermal therapy. Keywords: light triggered, near-infrared light, tumor-specific, multimodal imaging, photothermal therapy, contrast agents

  5. Construct Validity of Three Self-Report Measures of Creativity.

    Science.gov (United States)

    Fleenor, John W.; Taylor, Sylvester

    1994-01-01

    Relations were examined among the CPI Creativity Scale (CPI-CT), the MBTI Creativity Index (MBTI-CI), and the Kirton Adaption-Innovation Inventory (KAI; a style measure of behavioral preference) for samples of 431 to 12,115 managers. KAI scores were related to CPI-CT and MBTI-CI creativity levels. (SLD)

  6. The role and significance of Luo Zhiyuan's Shu yi hui bian in the history of plague in Lingnan (south of the five ridges).

    Science.gov (United States)

    Li, H; Lai, W

    1999-04-01

    Being the earliest monograph on plague in China, Luo Zhiyuan's Shu yi hui bian, not included in the National Catalogue of TCM Books, include the following contents: personal idea on the etiology of plague; Luo's friend Wu Xuanchang' unpublished Shu yu zhi fa on the treatment and manifestations of plague; Luo's specific recipe for plague based on medified Wang Qingren's Jie du huo xue decoction based on Wang Qingrens yi lin gai cuo; therapy for critical cases; many therapies applied on Lingnan, including experimental recipes, external therapy, preventive methods, and preventing recurrence methods; Luo's special administrating methods, including persisting day-and-night method, immediate persisting method, single-dose persisting method, and double-dose persisting method. He also gave several cured case records. His book, featuring unique idea with good effect, was repeatedly printed and extensively distributed, exerting influence, more or less, on the plague monographs of later ages, and occupying important position in the history of plague on Lingnan and the whole country as well. His idea of "that poisons and static blood" in pathogenesis and therapeutic principle of antitoxicity and activating blood is coincided with the results of present day clinical and laboratory studies. His administration of medicines is heuristic to the therapy of critical cases with Chinese medicaments and to the recognition of pathogenesis, etiology, and treatment of modern plague as well as other diseases of similar etiology and pathognesis and is worth of further study.

  7. Pharmacokinetic determination of ephedrine in Herba Ephedrae and Wu Tou Tang decoctions in rats using ultra performance liquid chromatography tandem mass spectrometry.

    Science.gov (United States)

    Zheng, Zhijie; Yan, Tongmeng; Chen, Weiying; Ye, Ling; Tang, Lan; Liu, Zhongqiu

    2012-08-01

    A rapid and sensitive ultra performance liquid chromatography tandem mass spectrometry method was developed and validated for the determination and quantification of ephedrine in rat plasma samples. An Acquity UPLC BEH C18 column (1.7 μm, 2.1 mm × 50 mm) was used for chromatographic separation. Electrospray ionization in the positive mode was used, and the precursor-fragment ion pairs of m/z 166/148 and m/z 289/97 were adopted to characterize ephedrine and testosterone (internal standard), respectively. The method was validated using 10, 100 and 500 ng/mL of ephedrine. It demonstrated adequate levels of precision and accuracy, matrix effect, extraction recovery and stability. Linearity over the concentration range of 0.5-2000 ng/mL was acceptable with a correlation coefficient (r²) better than 0.990. To determine the pharmacokinetic behaviour of this sympathomimetic compound in the Sprague-Dawley rats, ephedrine hydrochloride, Herba Ephedrae single-herb and Wu Tou Tang decoctions were administered orally, and ephedrine hydrochloride was also administered by intravenous injection, and blood samples were collected over 24 h. Ephedrine was measured in plasma and pharmacokinetic parameters were determined by using the standard non-compartmental method and calculated by using Practical Pharmacokinetic Program-Version 87/97. The AUC(0-t) and T(max) values were significantly different (p Tang decoction compared to the other oral treatments, suggesting that some components in the decoction may reduce the bioavailability of ephedrine.

  8. FY 2000 report on the results of the joint research - Field test project on the photovoltaic power generation for public facility use; 2000 nendo kyodokenkyu gyomu seika hokokusho. Kokyo shisetsu you taiyoko hatsuden field test jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-05-01

    The paper arranged the FY 2000 results of the field test on the photovoltaic power generation for public facility use, etc. This report described in detail the results obtained at 237 places including the following: Social Welfare Corp. Seimei-kai, Kobe City (Hyogo Prefecture), Iitaka Town of Iinan County (Mie Prefecture), Kyushu Electric Safety Association, Educational Corp. Kongo Gakuen, Social Welfare Corp. Izumi-kai, Educational Corp. Shiobara Ikuei-kai, Educational Corp. Aiko Gakuen, Social Welfare Corp. Tachibana-kai, Cooperative Association Co-op Kobe, Social Welfare Corp. Hoshizuki-no-sato, Tochigi-Fuji Industrial Co., Hirabayashi Section of Gamo Town of Gamo County (Shiga Prefecture), Yanagawa City (Fukuoka Prefecture), Imadate City of Imadate County (Fukui Prefecture), Osaka Prefecture, Yamanashi Prefecture, Utazu Town of Ayauta County (Kagawa Prefecture), Educational Corp. Fukuyama Gakuen, New Energy Business Cooperative Association, Meitec Corp., Shikoku Medicom Co., Shizen Kobo Co., Educational Corp. Horikoshi Gakuen, Matama Town of Nishi-Kunisaki County (Oita Prefecture), Nio Town of Mitoyo County (Kagawa Prefecture), Educational Corp. Koshien Gakuin, Sansei Giken Co., Mitsui Greenland Co., AWI Mach Co., Nagoya City and Educational Corp. Kibogaoka Gakuen. (NEDO)

  9. Synergism and rules from combination of Baicalin, Jasminoidin and Desoxycholic acid in refined Qing Kai Ling for treat ischemic stroke mice model.

    Directory of Open Access Journals (Sweden)

    Jian Li

    Full Text Available Refined Qing-Kai-Ling (QKL, a modified Chinese medicine, consists of three main ingredients (Baicalin, Jasminoidin and Desoxycholic acid, plays a synergistic effect on the treatment of the acute stage of ischemic stroke. However, the rules of the combination and synergism are still unknown. Based on the ischemic stroke mice model, all different kinds of combination of Baicalin, Jasminoidin, and Desoxycholic acid were investigated by the methods of neurological examination, microarray, and genomics analysis. As a result, it confirmed that the combination of three drugs offered a better therapeutical effect on ischemic stroke than monotherapy of each drug. Additionally, we used Ingenuity pathway Analysis (IPA and principal component analysis (PCA to extract the dominant information of expression changes in 373 ischemia-related genes. The results suggested that 5 principal components (PC1-5 could account for more than 95% energy in the gene data. Moreover, 3 clusters (PC1, PC2+PC5, and PC3+PC4 were addressed with cluster analysis. Furthermore, we matched PCs on the drug-target networks, the findings demonstrated that Baicalin related with PC1 that played the leading role in the combination; Jasminoidin related with PC2+PC5 that played a compensatory role; while Desoxycholic acid had the least performance alone which could relate with PC3+PC4 that played a compatible role. These manifestations were accorded with the principle of herbal formulae of Traditional Chinese Medicine (TCM, emperor-minister-adjuvant-courier. In conclusion, we firstly provided scientific evidence to the classic theory of TCM formulae, an initiating holistic viewpoint of combination therapy of TCM. This study also illustrated that PCA might be an applicable method to analyze the complicated data of drug combination.

  10. A Study on the Establishment of Pochonka and Chonmun yucho in the Early Choson Dynasty

    Science.gov (United States)

    Ahn, Sang-Hyeon

    2009-12-01

    We investigated the formation of Pochonka (Song of the Sky Pacers) and Chonmun yucho (Selected and classified writings on astrology) of the early Choson dynasty. We recognized that the songs in these books were deeply influenced by those in a Chinese book Tong-zhi published in 1161 A.D., based on the following facts; the contents of both treatises are described in the same order; the first phrase of the song for Thai-wei-yuan has composed of five words rather than seven words; in particular, Choson's Pochonka has the song that describes the position of the Milky Way relative to asterisms, which was supplemented by the author Zheng Qiao. Since Tong-zhi were brought into Koryo in 1364 A.D., Choson's Pochonka must be formed after that time. In particular, compared with Chinese Pu-tien-ko, Choson's Pochonka stresses the colors of asterisms in order to represent the origin of each asterism with respect to the astronomers, Shih-shen, Kan-te, and Wu-Hsien. We also find that the star-charts in Pochonka and Chonsang-yolcha-punyajido (Chart of the asterisms and the regions they govern) published in the early Choson dynasty are significantly similar in names, number of stars, and shapes of asterisms in them. This fact means that the star-charts in Pochonka originated from either the parent chart of Chonsang-yolcha-punyajido or Chonsang-yolcha-punyajido itself. The parent rubbing was reappeared in 1392 A.D. and carved on stele in 1396 A.D., and so the publication of Pochonka can be dated back to A.D. 1392. Chonmun yucho is a book that was formed by footnoting Pochonka with astrological descriptions in Chinese treatises. The formation period of Chonmun yucho is estimated to be 1440-1450 A.D. from the facts such as the biographical survey of the author Yi Sunji. Furthermore, Pochonka was adopted as a textbook of the government service examination for the astronomy division in Soungwan or the Royal Bureau of Astronomy in 1430 A.D.. We inferred from these facts that Choson

  11. A Study on the Establishment of Pochonka and Chonmun yucho in the Early Choson Dynasty

    Directory of Open Access Journals (Sweden)

    Sang-Hyeon Ahn

    2009-12-01

    Full Text Available We investigated the formation of Pochonka (Song of the Sky Pacers and Chonmun yucho (Selected and classified writings on astrology of the early Choson dynasty. We recognized that the songs in these books were deeply influenced by those in a Chinese book Tong-zhi published in 1161 A.D., based on the following facts; the contnts of both treatises are described in the same order; the first phrase of the song for Thai-wei-yuan has composed of five words rather than seven words; in particular, Choson`s Pochonka has the song that describes the position of the Milky Way relative to asterisms, which was supplemented by the author Zheng Qiao. Since Tong-zhi were brought into Koryo in 1364 A.D., Choson`s Pochonka must be formed after that time. In particular, compared with Chinese Pu-tien-ko, Choson`s Pochonka stresses the colors of asterisms in order to represent the origin of each asterism with respect to the astronomers, Shih-shen, Kan-te, and Wu-Hsien. We also find that the star-charts in Pochonka and Chonsang-yolcha-punyajido (Chart of the asterisms and the regions they govern published in the early Choson dynasty are significantly similar in names, number of stars, and shapes of asterisms in them. This fact means that the star-charts in Pochonka originated from either the parent chart of Chonsang-yolcha-punyajido or Chonsang-yolcha-punyajido itself. The parent rubbing was reappeared in 1392 A.D. and carved on stele in 1396 A.D., and so the publication of Pochonka can be dated back to A.D. 1392. Chonmun yucho is a book that was formed by footnoting Pochonka with astrological descriptions in Chinese treatises. The formation period of Chonmun yucho is estimated to be 1440-1450 A.D. from the facts such as the biographical survey of the author Yi Sunji. Furthermore, Pochonka was adopted as a textbook of the government service examination for the astronomy division in Soungwan or the Royal Bureau of Astronomy in 1430 A.D.. We inferred from these facts

  12. Algasid etendustesarja "Suveaaria 2009" proovid / Silja Joon

    Index Scriptorium Estoniae

    Joon, Silja, 1966-

    2009-01-01

    10. juulist 10. augustini Pärnu Vanalinna Põhikooli õuel toimuvast Pärnu Ooperi korraldatavast etendustesarjast "Suveaaria", mille raames tuuakse installatsioon-ooperite sarjas "Kataloog" uuena välja soprani ja tenori duettide projekt "Armustseene kvaliteetooperitest" (laulavad Kai Kallastu ja Roland Liiv, etenduse lavastaja on koreograaf Kaspar Aus, kunstnik Pille Neeve, muusikalise lahenduse eest vastutavad heliloojad Andrus Kallastu ja Hans-Gunter Lock ning pianist Jorma Toots). Korratakse "Hullumisstseene kvaliteetooperitest" (esinevad sopran Kai Kallastu ja flötist Leonora Palu) ja eelmisel aastal mudaravilasse komponeeritud Locki eksperimentaalset muusikateatrietendust "Mudamuusikateraapia laboratoorium". Esitatakse Andrus Kallastu loomingul põhinev müsteerium "Valgus ja vari", milles kõlab "Stabat mater" elektroonikale, "Stabat mater" häälele (laulab Kai Kallastu, saateks Anima Mea elektroonika)

  13. El Informe Valech y la tortura masiva y sistemática como crimen contra la humanidad cometido en Chile durante el régimen militar. Su enjuiciamiento desde la perspectiva del derecho penal internacional: Apuntes a propósito de la obra del Prof. Dr. Kai Ambos, Der Allgemeine Teil des Völkerstrafrechts, 2 ed., Duncker und Humblot, Berlín 2004, 1058 páginas

    Directory of Open Access Journals (Sweden)

    Jean Pierre Matus A.

    2005-01-01

    Full Text Available En este artículo se reseña el texto del Prof. Dr. Kai Ambos, Der Allgemeine Teil des Völkerstrafrechts y, al mismo tiempo, se propone la aplicación de los principales resultados de esa obra para un eventual enjuiciamiento de la tortura masiva y sistemática aplicada en Chile entre 1973 y 1990, tal y como se describe en el Informe de la Comisión Nacional de Prisión Política y Tortura (Informe Valech. Así, se comienza describiendo y analizando la sistematización propuesta por Ambos para una parte general del derecho penal internacional, luego se analiza la tortura como crimen contra la humanidad, sujeto a las reglas del derecho penal internacional. En este apartado se determinan sus elementos principales (el carácter masivo y sistemático, el Tribunal competente en Chile para conocer de estas causas y el procedimiento aplicable. A continuación se describen los hechos, tal y como se dieron a conocer en el Informe Valech, que permiten concluir que en Chile se aplicó la tortura de manera masiva y sistemática durante el régimen militar, favorecida por éste, mediante el establecimiento de una "maquinaria" de represión "legalizada". Enseguida, se determina la existencia de una responsabilidad penal internacional individual derivada de estos hechos, para, a continuación, pasar a analizar los principales problemas de la parte general del derecho penal internacional que se presentarían en el caso de juzgarse tales responsabilidades individuales, siguiendo el esquema de análisis en dos niveles propuesto por Kai Ambos, a saber, discutiendo primero los presupuestos objetivos y subjetivos de esa responsabilidad, para finalizar analizando las principales defensas que podrían oponerse por los eventuales acusados.This article reviews Prof. Dr. Kai Ambos' book, Der Allgemeine Teil des Völkerstrafrechts, and proposes the application of the main results of this book to the possible trial of the acts of massive and systematic torture carried out

  14. Clinical, pathological, and radiological characteristics of solitary ground-glass opacity lung nodules on high-resolution computed tomography

    Directory of Open Access Journals (Sweden)

    Qiu ZX

    2016-09-01

    Full Text Available Zhi-Xin Qiu,1 Yue Cheng,1 Dan Liu,1 Wei-Ya Wang,2 Xia Wu,2 Wei-Lu Wu,2 Wei-Min Li1,2 1Department of Respiratory Medicine, 2Department of Pathology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China Background: Lung nodules are being detected at an increasing rate year by year with high-resolution computed tomography (HRCT being widely used. Ground-glass opacity nodule is one of the special types of pulmonary nodules that is confirmed to be closely associated with early stage of lung cancer. Very little is known about solitary ground-glass opacity nodules (SGGNs. In this study, we analyzed the clinical, pathological, and radiological characteristics of SGGNs on HRCT.Methods: A total of 95 resected SGGNs were evaluated with HRCT scan. The clinical, pathological, and radiological characteristics of these cases were analyzed.Results: Eighty-one adenocarcinoma and 14 benign nodules were observed. The nodules included 12 (15% adenocarcinoma in situ (AIS, 14 (17% minimally invasive adenocarcinoma (MIA, and 55 (68% invasive adenocarcinoma (IA. No patients with recurrence till date have been identified. The positive expression rates of anaplastic lymphoma kinase and ROS-1 (proto-oncogene tyrosine-protein kinase ROS were only 2.5% and 8.6%, respectively. The specificity and accuracy of HRCT of invasive lung adenocarcinoma were 85.2% and 87.4%. The standard uptake values of only two patients determined by 18F-FDG positron emission tomography/computed tomography (PET/CT were above 2.5. The size, density, shape, and pleural tag of nodules were significant factors that differentiated IA from AIS and MIA. Moreover, the size, shape, margin, pleural tag, vascular cluster, bubble-like sign, and air bronchogram of nodules were significant determinants for mixed ground-glass opacity nodules (all P<0.05.Conclusion: We analyzed the clinical, pathological, and radiological characteristics of SGGNs on HRCT and found that the size, density

  15. Values,Thought Patterns and Personality Interpretation Method of Chinese Philosophy:A Case Study of Philosophical Interpretation of Li Zhi%价值观念、思维模式与中国哲学的人格诠释法--以李贽哲学与人生的诠释为例

    Institute of Scientific and Technical Information of China (English)

    李煌明

    2014-01-01

    As the personality problems of being a man with virtue is the core of Chinese philosophy ,the corre-sponding interpretation method of Chinese philosophy should be around the"personality",namely"personality in-terpretation method ."This interpretation method ,with traditional values and thinking mode for the kernel ,expands the two dimensions of ideal personality and real personality ,that is ,the transcendental life and natural reality ,and reveals the characteristics of Chinese philosophy ,the spirit of the nation and the presence of civilization .Take Li Zhi's philosophy as an example ,the Theory of Preserving Childlike Innocence embodies his true personality ;the inte-gration of"Empty (true)-Death (real)-know (new )"is its intrinsic thinking modes;"On Heroes"embodies his un-inhibited but promising personality with the ideas of contradictions and diversities .Its corresponding ideal personali-ty ,a real-life Li Zhi ,is a true maverick with courage and justice ,and a person who seems to be beyond the material world but actually concerns about the people .%“成人”“成德”的人格问题是中国哲学的核心内容,与此相应,中国哲学的诠释方法亦应围绕“人格”这一核心展开,此即“人格诠释法”。此诠释方法,以传统价值观念和思维模式为内核,从理想人格与现实人格即超越的生命与现实的生活二个层面展开,从而彰显中国哲学之特质、民族之精神与文明之面貌。以李贽哲学观之,“童心说”体现的是其真实日新的人格,“空(真)-寂(实)-知(新)”三者圆融是其内在思维模式;而“豪杰论”体现的是狂狷有为人格,“有两有对”“各异其性”是其内在思维模式。与其理想人格相应,现实生活中的李贽是一个标新立异而既方又直,“身游物外”而“心切救民”之人。

  16. Structural and Biochemical Characterization of BdsA from Bacillus subtilis WU-S2B, a Key Enzyme in the “4S” Desulfurization Pathway

    Directory of Open Access Journals (Sweden)

    Tiantian Su

    2018-02-01

    Full Text Available Dibenzothiophene (DBT and their derivatives, accounting for the major part of the sulfur components in crude oil, make one of the most significant pollution sources. The DBT sulfone monooxygenase BdsA, one of the key enzymes in the “4S” desulfurization pathway, catalyzes the oxidation of DBT sulfone to 2′-hydroxybiphenyl 2-sulfonic acid (HBPSi. Here, we determined the crystal structure of BdsA from Bacillus subtilis WU-S2B, at the resolution of 2.2 Å, and the structure of the BdsA-FMN complex at 2.4 Å. BdsA and the BdsA-FMN complex exist as tetramers. DBT sulfone was placed into the active site by molecular docking. Seven residues (Phe12, His20, Phe56, Phe246, Val248, His316, and Val372 are found to be involved in the binding of DBT sulfone. The importance of these residues is supported by the study of the catalytic activity of the active site variants. Structural analysis and enzyme activity assay confirmed the importance of the right position and orientation of FMN and DBT sulfone, as well as the involvement of Ser139 as a nucleophile in catalysis. This work combined with our previous structure of DszC provides a systematic structural basis for the development of engineered desulfurization enzymes with higher efficiency and stability.

  17. Wake-up radio systems : design, development, performance evaluation and comparison to conventional medium access control protocols for wireless sensor networks

    OpenAIRE

    Oller i Bosch, Joaquim

    2015-01-01

    During the recent years, the research related to Wake-up Radio (WuR) systems has gained noticeable interest. In WuR systems, a node initiating a communication first sends a Wake-up Call (WuC) by means of its Wake-up Transmitter (WuTx), to the Wake-up Receiver (WuRx) of a remote node to activate it in an on-demand manner. Until the reception of the WuC, the node's MCU and main data transceiver are in sleep mode. Hence, WuR drastically reduce the power required by wireless nodes. This thesis...

  18. Effect of Jian-Pi-Zhi-Dong Decoction on striatal glutamate and γ-aminobutyric acid levels detected using microdialysis in a rat model of Tourette syndrome

    Directory of Open Access Journals (Sweden)

    Zhang W

    2016-05-01

    Full Text Available Wen Zhang,1,* Li Wei,2,* Wenjing Yu,1 Xia Cui,1 Xiaofang Liu,2 Qian Wang,1 Sumei Wang2 1Department of Pediatrics, The Third Affiliated Hospital, 2Department of Pediatrics, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China *These authors contributed equally to this work Background: Jian-Pi-Zhi-Dong Decoction (JPZDD is a dedicated treatment of Tourette syndrome (TS. The balance of neurotransmitters in the cortico-striato-pallido-thalamo-cortical network is crucial to the occurrence of TS and related to its severity. This study evaluated the effect of JPZDD on glutamate (Glu and γ-aminobutyric acid (GABA and their receptors in a TS rat model.Materials and methods: Rats were divided into four groups (n=12 each. TS was induced in three of the groups by injecting them with 3,3'-iminodipropionitrile for 7 consecutive days. Two model groups were treated with tiapride (Tia or JPZDD, while the control and the remaining model group were gavaged with saline. Behavior was assessed by stereotypic score and autonomic activity. Striatal Glu and GABA contents were detected using microdialysis. Expressions of N-methyl-D-aspartate receptor 1 and GABAA receptor (GABAAR were observed using Western blot and real-time polymerase chain reaction.Results: Tia and JPZDD groups had decreased stereotypy compared with model rats; however, the JPZDD group showed a larger decrease in stereotypy than the Tia group at a 4-week time point. In a spontaneous activity test, the total distance of the JPZDD and Tia groups was significantly decreased compared with the model group. The Glu levels of the model group were higher than the control group and decreased with Tia or JPZDD treatment. The GABA level was higher in the model group than the control group. Expressions of GABAAR protein in the model group were higher than in the control group. Treatment with Tia or JPZDD reduced the expression of GABAAR protein. In the case of the m

  19. Impact of Flight Departure Delay on Airline Choice Behavior

    Directory of Open Access Journals (Sweden)

    Taylor Tae-Hwee Lee

    2017-12-01

    Full Text Available The Korean aviation industry (KAI has been expanded significantly, because the Incheon International Airport opened in 2001 and low cost carriers (LCC entered the KAI market. But following the KAI's growth, flight departure delays (FDDs have increased six-fold during the past decade. In terms of these situations, this study firstly adds the FDD variable to an airline choice behavior (ACB model and secondly analyses how FDD impact the ACB. As a result, FDD is relatively less influential on ACB than other attributes. Both the flight service and available schedule are positively related to the choice of full service carriers (FSC. The analysis shows that FSCs’ allotment rate (AR is 85.3%, while LCCs’ one is 14.7%.

  20. Identification of Multiple Ingredients for a Traditional Chinese Medicine Preparation (Bu-yang-huan-wu-tang by Liquid Chromatography Coupled with Tandem Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Tung-Hu Tsai

    2013-09-01

    Full Text Available Bu-yang-huan-wu-tang (BYHWT is a popular Traditional Chinese Medicine formula consisting of seven herbal medicines (Astragalus membranaceus, Angelica sinensis, Paeonia lactiflora, Ligusticum chuanxiong, Carthamus tinctorius, Amygdalus persica and Pheretima aspergillum, that has been used in China for centuries to overcome stroke-induced disability. To ensure the consistency of quality, a reliable analytical method is required, therefore, we developed a liquid chromatography with tandem mass spectrometry (LC-MS/MS method for quantitative analysis of the major constituents in BYHWT. The herbal ingredients consisting of the cycloartane-type triterpene glycosides of astragaloside I, astragaloside II and astragaloside IV; isoflavones of formononetin, ononin calycosin, calycosin-7-O-β-d-glucoside; ligustilide and paeoniflorin were separated on a C18 column with gradient elution of methanol/10 mM ammonium acetate buffer–formic acid (100:0.1, v/v. This study was performed by a mass spectrometer using electrospray ionization (ESI with positive ionization ions monitored in the multiple reaction-monitoring (MRM mode. The linearity, accuracy, precision, limit of detection (LOD and lower limit of quantification (LLOQ were validated for this quantification method, and the sensitivity, reliability and reproducibility were all confirmed. The experiments provided a good method for analyzing BYHWT extracts. This study also quantitated the active components in various brands of commercially available products. The results indicated that the pharmaceutical industrial products of BYHWT exhibited considerable variation in their contents of the herbal compounds.

  1. Contamination and Human Health Risk Assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in Oysters After the Wu Yi San Oil Spill in Korea.

    Science.gov (United States)

    Loh, Andrew; Yim, Un Hyuk; Ha, Sung Yong; An, Joon Geon; Kim, Moonkoo

    2017-07-01

    After the collision of the Singapore-registered oil tanker M/V Wu Yi San into the oil terminal of Yeosu, Korea on January 31, 2014, approximately 900 m 3 of oil and oil mixture were released from the ruptured pipelines. The oil affected more than 10 km of coastline along Gwangyang Bay. Emergency oil spill responses recovered bulk oil at sea and cleaned up the stranded oil on shore. As part of an emergency environmental impact assessment, region-wide monitoring of oil contamination in oyster had been conducted for 2 months. Highly elevated concentrations of polycyclic aromatic hydrocarbons (PAHs) were detected at most of the spill affected sites. Four days after the spill, the levels of PAHs in oysters increased dramatically to 627-81,000 ng/g, the average of which was 20 times higher than those found before the spill (321-4040 ng/g). The level of PAHs in these oysters increased until 10 days after the spill and then decreased. Due to the strong tidal current and easterly winter winds, the eastern part of the Bay-the Namhae region-was heavily contaminated compared with other regions. The accumulation and depuration of spilled oil in oyster corresponded with the duration and intensity of the cleanup activities, which is the first field observation in oil spill cases. Human health risk assessments showed that benzo[a]pyrene equivalent concentrations exceeded levels of concern in the highly contaminated sites, even 60 days after the spill.

  2. Up regulation of K A I 1 gene expression and apoptosis effect of imatinib mesylate in gastric adenocarcinoma (AGS cell line

    Directory of Open Access Journals (Sweden)

    eyed Ataollah Sadat Shandiz

    2016-02-01

    Full Text Available Objective: To evaluate the effect of imatinib mesylate on KAI1 gene expression and apoptosis properties in human gastric carcinoma AGS cell line. Methods: Cell viability was assessed by MTT assay and quantitative real time PCR method was applied for investigation of Bax, Bcl-2, and KAI1 gene expression in AGS cells. The quantity of KAI1, Bax, and Bcl-2 compared to GAPDH gene expressions were examined using the formula 2-∆∆Ct. Furthermore, cell apoptosis/necrosis was carried out by annexin V/PI staining and quantified with flow cytometry after treatment with imatinib. Results: Imatinib mesylate was showed to have a dose-dependent toxicity effect against AGS cells. KAI1/GAPDH gene expression ratios were 1.07 ± 0.02 (P > 0.05, 1.68 ± 0.19 (P > 0.05, 3.60 ± 0.55 (P < 0.05, 6.54 ± 0.27 (P < 0.001 for 20, 50, 80 and 100 μmol/L of imatinib concentrations. The mRNA levels of Bax detected by real-time PCR after treatment with imatinib mesylate were significantly increased. Also, the number of apoptotic cells was increased from 3.72% (statistically significant; P < 0.05 in untreated AGS cells to 21.72%, 83.04% and 85.80%, respectively, following treatment with 20, 40, and 60 μmol/L imatinib mesylate. Conclusions: The results suggest that imatinib mesylate can induce apoptosis pathway in a dose-dependent mode and might modulate metastasis by up regulating KAI1 gene expression in human gastric carcinoma AGS cell line.

  3. The effects of hydrogen peroxide on the circadian rhythms of Microcystis aeruginosa.

    Directory of Open Access Journals (Sweden)

    Haifeng Qian

    Full Text Available BACKGROUND: The cyanobacterium Microcystis aeruginosa is one of the principal bloom-forming cyanobacteria present in a wide range of freshwater ecosystems. M. aeruginosa produces cyanotoxins, which can harm human and animal health. Many metabolic pathways in M. aeruginosa, including photosynthesis and microcystin synthesis, are controlled by its circadian rhythms. However, whether xenobiotics affect the cyanobacterial circadian system and change its growth, physiology and biochemistry is unknown. We used real-time PCR to study the effect of hydrogen peroxide (H(2O(2 on the expression of clock genes and some circadian genes in M. aeruginosa during the light/dark (LD cycle. RESULTS: The results revealed that H(2O(2 changes the expression patterns of clock genes (kaiA, kaiB, kaiC and sasA and significantly decreases the transcript levels of kaiB, kaiC and sasA. H(2O(2 treatment also decreased the transcription of circadian genes, such as photosynthesis-related genes (psaB, psbD1 and rbcL and microcystin-related genes (mcyA, mcyD and mcyH, and changed their circadian expression patterns. Moreover, the physiological functions of M. aeruginosa, including its growth and microcystin synthesis, were greatly influenced by H(2O(2 treatment during LD. These results indicate that changes in the cyanobacterial circadian system can affect its physiological and metabolic pathways. CONCLUSION: Our findings show that a xenobiotic can change the circadian expression patterns of its clock genes to influence clock-controlled gene regulation, and these influences are evident at the level of cellular physiology.

  4. Antihepatoma and Liver Protective Potentials of Ganoderma Lucidum (靈芝 Ling Zhi Fermented in a Medium Containing Black Soybean (黑豆 Hēi Dòu and Astragalus Membranaceus (生黃耆 Shēng Huáng Qí

    Directory of Open Access Journals (Sweden)

    Zheng-Yuan Su

    2013-04-01

    Full Text Available The antihepatoma activity and liver protective function of the fermentation products (5 L fermenator of Ganoderma lucidum (GL; 靈芝 Ling Zhi cultivated in a medium containing black soybean (BS; 黑豆 Hēi Dòu and Astragalus membranaceus (AM; 生黃耆 Shēng Huáng Qí at different fermentation temperatures were investigated in this study. Hep 3B cells pretreated with lovastatin were used to study the antihepatoma activity, and possible active components were analyzed by reverse-phase high-performance liquid chromatography. Carbon tetrachloride (CCl4-induced primary rat hepatocyte injury was further used to evaluate the liver protective activity of the fermentation products. While all the GL broth filtrates do not inhibit the growth of Hep 3B cells, the ethanolic extract from GL-2 mycelia (GL-2-mE, cultivated in the medium containing BS (50 g/L and AM (20 g/L at 24 °C for 11 days showed the best antihepatoma activity (IC50 26.6 μg/mL than the other ethanolic extracts from GL mycelia, GL fruiting body, BS, and AM did. The antihepatoma activities were correlated with some unknown active components in these samples. Furthermore, GL-2-mE (100 μg/mL without harmful effect on the growth of normal primary rat hepatocytes significantly maintained cell viability, reduced lactate dehydrogenase leakage, lowered lipid peroxidation, and increased glutathione peroxidase and glutathione S-transferase activities in the CCl4-induced damaged primary rat hepatocytes.

  5. Low power high growth rate deposition of microcrystalline silicon

    OpenAIRE

    Feltrin, A; Bugnon, G; Meillaud, F; Bailat, J; Ballif, C

    2008-01-01

    Microcrystalline growth regimes and solar cells obtained in different pressure and silane depletion conditions are studied in a large area KAI-S plasma reactor. The microcrystalline material quality is systematically investigated by Fourier Transform Photocurrent Spectroscopy (FTPS) to evaluate the defect density. It is shown that higher pressure and silane depletion positively affect the material quality. A clear correlation between FTPS measurements and cell efficiency is established, showi...

  6. [Safety grade of application of traditional Chinese medicines during pregnancy].

    Science.gov (United States)

    Wang, Yu-Guang; Jin, Rui; Kong, Xiang-Wen; Zhang, Bing

    2016-01-01

    The efficacy and safety of application of traditional Chinese medicines (TCMs) during the pregnancy is a hotspot among scholars. However, the traditional pregnancy contraindication content has certain historical limitations, and cannot meet the needs of the current pregnant women for rational drug use. We need to refine and interpret it with modern medical science. In this paper, we summarized the ancient and modern knowledge about pregnancy contradiction and tried to establish a grading safety system, based on the actual clinical practices and thte medication grading concept of western medicines. Specifically speaking, in this paper, we compared the connotations of forbidden/contradiction and cautious use, and focused on the safe herbs that included in the prescriptions for dietary therapy. Meanwhile, in this paper, we summarized the core content of the famous theories of ″You Gu Wu Yun (pregnancy disease)″ and ″Shuai Qi Da Ban Er Zhi (therapy during pregnancy)″, and studied the dangerous and unknown risk of TCMs during pregnancy. At last, a five-grade safety system of TCMs applied on the pregnant women was established, including forbidden, contraindicated, cautious, uncertain and available medicines. We classified medicines with the embryotoxicity (e.g. teratogenic, mutagenic, ageneisa), the traditional toxicity (e.g. abortion), the fierce herbal property (e.g. removing blood stasis, promoting Qi circulation) and reliable edible medicinal herbs. We also place an ″uncertain″ category based on objective reality. Meanwhile, 33 sample TCMs were preliminarily determined. This paper proposed the preference and ideas for the rational herbal use in pregnancy. Copyright© by the Chinese Pharmaceutical Association.

  7. Nine Years of Cooperation: The US-German Memorandum of Understanding (MoU) on Helicopter Aeromechanics 2003-2012

    Science.gov (United States)

    2013-12-01

    qualities of side-stick controlled helicopters was given the “Ian Cheeseman Best Paper Award” at the Eu - ropean Rotorcraft Forum 2012. ii    As...Forum of the AHS, Phoenix, 2006 35    [22] Gardner, Anthony D., Richter, Kai, Rosemann, Henning : Simulation of Oscillat- ing Airfoils and Moving Flaps...Numerical Methods, 65th Annual Forum of the AHS, Grape- vine, TX, 2009 [26] Gardner, Anthony D., Richter, Kai, Rosemann, Henning : Numerical Investiga

  8. Metabonomics Combined with UPLC-MS Chemical Profile for Discovery of Antidepressant Ingredients of a Traditional Chinese Medicines Formula, Chaihu-Shu-Gan-San

    Directory of Open Access Journals (Sweden)

    Hongmei Jia

    2013-01-01

    Full Text Available This study proposed a new strategy for uncovering the active chemical constituents of a traditional Chinese medicines (TCMs formula, Chaihu-Shu-Gan-San (CSGS. Metabonomics and chemical profile were integrated in combination with the multivariate statistical analysis (MVA to discover the chemical constituents which contribute to the antidepressant effect of CSGS. Based upon the difference between CSGS and QZ (CSGS without Zhi-Qiao extracts in the chemical profiles and the regulations of metabolic disturbances induced by CUMS, synephrine, naringin, hesperidin, and neohesperidin were recognized as the active constituents of CSGS from Zhi-qiao responsible for those missing regulations of CSGS when Zhi-Qiao was subtracted from the whole formula. They participated in the regulations of the deviated metabolites 2–4, 10–14, and 22–25, involved in metabolic pathways of ketone bodies synthesis, phenylalanine, tyrosine and tryptophan biosynthesis, valine, aspartate, glutamate metabolism, and glycolysis/gluconeogenesis. Furthermore, the assay of MAO-A activity confirmed the potential antidepressant effect of naringin and its active sites on the MAO-A was inferred by molecular docking study. The integration of metabonomics and chemical profile was proved to be a useful strategy for uncovering what the active chemical constituents in TCM formula are and how they make contributions for the efficacy of the formula.

  9. Taxonomic notes on Neoperla (Plecoptera: Perlidae) from Sichuan Province of China with the description of two new species.

    Science.gov (United States)

    Li, Weihai; Wang, Ying; Wang, Rongfeng

    2017-01-17

    Species of the perlid genus Neoperla from Sichuan Province, China are reviewed. Two new species are described, Neoperla caii Li & Wang, sp. nov. and N. emeishana Li & Wang, sp. nov. The new species are compared with related congeners. Available types of several known Neoperla species from Sichuan Province were studied and complementary descriptions or brief taxonomic comments are presented for N. bilineata Wu & Claassen, N. chui Wu & Claassen, N. microtumida Wu & Claassen, N. quadrata Wu & Claassen and N. truncata Wu.

  10. Roles of Tunneling, Multiphoton Ionization, and Cascade Ionization for Femtosecond Optical Breakdown in Aqueous Media

    Science.gov (United States)

    2009-09-01

    This implies that a kinetic energy of Ecrit = 1.5 ~ is required for impact ionization [Kai00, Ret04]. The excess energy of 0.5  ~ that remains... Ecrit because the impact ioni- zation rate increases with kinetic energy [Arn92, Kai00, Kel60, Ret04]. To consider both factors, we assume that the...but then neglect it in their theoretical treatment of breakdown [Spa81]. The first comprehensive rate equation model including multiphoton and

  11. Effects of three warm-up regimens of equal distance on VO2 kinetics during supramaximal exercise in Thoroughbred horses.

    Science.gov (United States)

    Mukai, K; Hiraga, A; Takahashi, T; Ohmura, H; Jones, J H

    2010-11-01

    Several studies have indicated that even low-intensity warm-up increases O(2) transport kinetics and that high-intensity warm-up may not be needed in horses. However, conventional warm-up exercise for Thoroughbred races is more intense than those utilised in previous studies of equine warm-up responses. To test the hypothesis that warm-up exercise at different intensities alters the kinetics and total contribution of aerobic power to total metabolic power in subsequent supramaximal (sprint) exercise in Thoroughbred horses. Nine well-trained Thoroughbreds ran until fatigue at 115% of maximal oxygen consumption (VO2max) 10 min after warming-up under each of 3 protocols of equal running distance: 400 s at 30% VO2max (LoWU), 200 s at 60% VO2max (MoWU) and 120 s at 100% VO2max (HiWU). Variables measured during exercise were rates of O(2) and CO(2) consumption/production (VO2,VO2), respiratory exchange ratio (RER), heart rate, blood lactate concentration and accumulation rate and blood gas variables. VO2 was significantly higher in HiWU than in LoWU at the onset of the sprint exercise and HR was significantly higher in HiWU than in LoWU throughout the sprint. Accumulation of blood lactate, RER, P(a)CO(2) and PvCO2 in the first 60 s were significantly lower in HiWU than in LoWU and MoWU. There were no significant differences in stroke volume, run time or arterial-mixed venous O(2) concentration. These results suggest HiWU accelerates kinetics and reduces reliance on net anaerobic power compared with LoWU at the onset of the subsequent sprint. © 2010 EVJ Ltd.

  12. Maintaining an outward image: a Korean immigrant's life with type 2 diabetes mellitus and hypertension.

    Science.gov (United States)

    Pistulka, Gina M; Winch, Peter J; Park, Hyunjeong; Han, Hae-Ra; Kim, Miyong T

    2012-06-01

    Type 2 diabetes mellitus (DM) and hypertension (HTN) disproportionately affect minority populations in the United States, including Korean American immigrants (KAI). We conducted qualitative interviews with middle-aged KAI in Maryland living with DM and HTN to examine the illness experience to inform future intervention strategies. Study results show that participants utilized strategies to maintain respect and Korean identity, including an image of being healthy and in control of their behavior in the public arena. These strategies included the lack of disclosure of their illness, even to family members, and avoiding outside assistance when engaging in problem solving. Maintaining an outward image of health was a common goal that affected the self-care of KAI in this study, a finding that might prove significant in the management of other chronic illnesses affecting this population. The study findings demonstrate the importance of in-depth understanding of specific populations when treating chronic illness, and caretakers' sensitivity to each population's unique cultural issues regarding identity, image, and disclosure.

  13. The (temporary?) queering of Japanese TV.

    Science.gov (United States)

    Miller, S D

    2000-01-01

    One of the primary texts of the "out" queer cinema of Japan is the television serial D s kai, first aired in 1993. Unlike Western television shows positing queer characters, D s kai presents its gay characters without apology or excuses, and as leads rather than as colorful appendages. At the same time, however, the show filters gay eroticism through the (hetero)normative mode of serial melodrama, at once pushing the boundaries of national permissiveness while normalizing and homogenizing homosexuality by rendering it within a conventional form.

  14. [A molecular epidemiological study of KI polyomavirus and WU polyomavirus in children with acute respiratory infection in Tianjin, China].

    Science.gov (United States)

    Lin, Shu-Xiang; Wang, Wei; Guo, Wei; Yang, Hong-Jiang; Ma, Bai-Cheng; Fang, Yu-Lian; Xu, Yong-Sheng

    2017-07-01

    To investigate the relationship of KI polyomavirus (KIPyV) and WU polyomavirus (WUPyV) with acute respiratory infection in children in Tianjin, China. A total of 3 730 nasopharyngeal secretions were collected from hospitalized children with acute respiratory infection in Tianjin Children's Hospital from January 2011 to December 2013. Viral nucleic acid was extracted, and virus infection (KIPyV and WUPyV) was determined by PCR. Some KIPyV-positive and WUPyV-positive PCR products were subjected to sequencing. Sequencing results were aligned with the known gene sequences of KIPyV and WUPyV to construct a phylogenetic tree. Amplified VP1 fragments of KIPyV were inserted into the cloning vector (PUCm-T) transformed into E. coli competent cells. Positive clones were identified by PCR and sequencing. The nucleotide sequences were submitted to GenBank. In addition, another seven common respiratory viruses in all samples were detected by direct immunofluorescence assay. In the 3 730 specimens, the KIPyV-positive rate was 12.14% (453/3 730) and the WUPyV-positive rate was 1.69% (63/3 730). The mean infection rate of KIPyV was significantly higher in June and July, while the mean infection rate of WUPyV peaked in February and March. Most of the KIPyV-positive or WUPyV-positive children were infections with KIPyV, WUPyV, and other respiratory viruses were observed in the children. The co-infection rate was 2.31% (86/3 730) and there were nine cases of co-infections with WUPyV and KIPyV. Thirty-five KIPyV-positive and twelve WUPyV-positive PCR products were sequenced and the alignment analysis showed that they had high homology with the known sequences (94%-100% vs 95%-100%). The VP1 gene sequences obtained from two KIPyV strains in this study were recorded in GenBank with the accession numbers of KY465925 and KY465926. For some children with acute respiratory infection in Tianjin, China, the acute respiratory infection may be associated with KIPyV and WUPy

  15. ACUTE EFFECTS OF STATIC STRETCHING, DYNAMIC EXERCISES, AND HIGH VOLUME UPPER EXTREMITY PLYOMETRIC ACTIVITY ON TENNIS SERVE PERFORMANCE

    Directory of Open Access Journals (Sweden)

    Ertugrul Gelen

    2012-12-01

    Full Text Available The purpose of this study was to compare the acute effects of static stretching; dynamic exercises and high volume upper extremity plyometric activity on tennis serve performance. Twenty-six elite young tennis players (15.1 ± 4.2 years, 167.9 ± 5.8 cm and 61.6 ± 8.1 kg performed 4 different warm-up (WU routines in a random order on non-consecutive days. The WU methods consisted of traditional WU (jogging, rally and serve practice (TRAD; traditional WU and static stretching (TRSS; traditional WU and dynamic exercise (TRDE; and traditional WU and high volume upper extremity plyometric activity (TRPLYP. Following each WU session, subjects were tested on a tennis serve ball speed test. TRAD, TRSS, TRDE and TRPLYO were compared by repeated measurement analyses of variance and post-hoc comparisons. In this study a 1 to 3 percent increase in tennis serve ball speed was recorded in TRDE and TRPLYO when compared to TRAD (p 0.05. ICCs for ball speed showed strong reliability (0.82 to 0.93 for the ball speed measurements.The results of this study indicate that dynamic and high volume upper extremity plyometric WU activities are likely beneficial to serve speed of elite junior tennis players.

  16. Klitika im Altpreußischen

    Directory of Open Access Journals (Sweden)

    Vytautas Rinkevičius

    2011-07-01

    Full Text Available KLITIKAI PRŪSŲ KALBOJESantraukaPrūsų kalbos III katekizmo rašyba leidžia pakankamai pagrįstai spėti, kad prūsų kalboje du kalbėjimo sraute susidūrę klitikai reguliariai sudarydavę atskirą taktinę grupę (fonologinį žodį, automatiškai kirčiuotą pirmajame skiemenyje. Reiškinys greičiausiai buvęs visiškai fonologinis ir nepriklausęs nuo semantinių ar sintaksinių grupę sudarančių žodžių ypatybių. Dėl nenuoseklios šaltinių rašybos pagrindiniu tokių taktinių grupių nustatymo kriterijumi laikytina ne tiek žodžių rašyba kartu, kiek netikėtas proklitiko kirtis. Dažniausiai tokį kirtį gauna prielinksniai konstrukcijose su vienskiemenėmis įvardžių formomis (pvz., ēnstan, tačiau lygiai taip pat gali būti paaiškintas ir jungtuko kāigi (greta kai kirčiavimas. Ne junginiuose su kitais klitikais tiek prielinksniai, tiek jungtukas kai niekada nebūna kirčiuoti. Tokie atvejai kaip prēistan klausīwingin, pērstans wāldnikans ir kt. rodo, kad klitikai sudarydavę savarankišką taktinę grupę, o ne kartu su nekirčiuotu akcentogeniniu žodžiu.

  17. Two new genera and three new species of Epipaschiinae Meyrick from China (Lepidoptera, Pyralidae

    Directory of Open Access Journals (Sweden)

    Mingqiang Wang

    2017-12-01

    Full Text Available Two new genera of Epipaschiinae are described. The genus Arcanusa Wang, Chen & Wu, gen. n. is established for Ar. apexiarcanusa Wang, Chen & Wu, sp. n. and Ar. sinuosa (Moore, 1888, comb. n., described in Scopocera Moore, 1888 (junior synonym of Stericta Lederer, 1863. The female genitalia of Ar. sinuosa (Moore, 1888, comb. n. are described for the first time. Androconia Wang, Chen & Wu, gen. n. is erected, including two new species, An. rallusa Wang, Chen & Wu, sp. n. and An. morulusa Wang, Chen & Wu, sp. n. Illustrations of all adults and their genitalia, and a key to the two new genera are provided.

  18. Freedom in the time of oppression in L. Gutauskas’ novels “Letters from Viešvilė” and “The Feathers”

    OpenAIRE

    Bernotienė, Gintarė

    2011-01-01

    In the novels "Laiškai iš Viešvilės" ("Letters from Viešvilė") and "Plunksnos" ("The feathers") Leonardas Gutauskas considers themes of freedom and artistic creation, which in certain political situation are closely related to the problem of individual freedom and restriction of liberty in the annexed country as well. According to the metaphor of the novel "Laiškai iš Viešvilės", in the time of oppression characters live their lives as bounded by wire mesh, and despite of that freedom in this...

  19. Simultaneous quantitation of polygalaxanthone III and four ginsenosides by ultra-fast liquid chromatography with tandem mass spectrometry in rat and beagle dog plasma after oral administration of Kai-Xin-San: application to a comparative pharmacokinetic study.

    Science.gov (United States)

    Lv, Chunxiao; Li, Qing; Zhang, Xiaowen; He, Bosai; Xu, Huarong; Yin, Yidi; Liu, Ran; Liu, Jingjing; Chen, Xiaohui; Bi, Kaishun

    2014-05-01

    A fast, selective, and quantitative ultra-fast liquid chromatography with tandem mass spectrometry method has been developed and validated for the simultaneous quantitation of polygalaxanthone III, ginsenoside Rb1, ginsenoside Rd, ginsenoside Re, and ginsenoside Rg1 in the plasma of rat and beagle dog after oral administration of Kai-Xin-San. After addition of the internal standard, salidroside, the plasma samples were extracted by liquid-liquid extraction and separated on a Venusil MP C18 column with methanol/0.01% acetic acid water as mobile phase. The tandem mass spectrometric detection was performed in the multiple reaction monitoring with turbo ion spray source in a switching ionization mode. The method was examined, and found to be precise and accurate with the linearity range of the compounds. The intra- and interday precision and accuracy of the analytes were well within acceptance criteria (±15%). The mean extraction recoveries of analytes and internal standard were all >75.0%. The validated method has been successfully applied to comparing pharmacokinetic profiles of analytes in rat and beagle dog plasma. The results indicated that no significant differences were observed in pharmacokinetic parameters of ginsenoside Rg1, while the others had significant differences, which may due to the different mechanisms of absorption and metabolism. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. 78 FR 9015 - Osage Negotiated Rulemaking Committee

    Science.gov (United States)

    2013-02-07

    ... 14, 2013, from 8 a.m. to 6 p.m. ADDRESSES: February Meeting: Wah Zha Zhi Cultural Center, 1449 W. Main, Pawhuska, Oklahoma 74056; March Meeting: Osage Casino Event Center, 951 W. 36 Street North, Tulsa...

  1. Anti-tumor activity of polysaccharides extracted from Senecio ...

    African Journals Online (AJOL)

    *, Bao Zhang, Mingming Han, Xin Jin, Liyuan Sun and Tao Li. Department of ..... Yang J, Li X, Xue Y, Wang N, Liu W. Anti-hepatoma activity and mechanism of corn ... Peng W, Wu JG, Jiang YB, Liu YJ, Sun T, Wu N, Wu CJ. Antitumor activity of ...

  2. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Dong Jun Jee1 Tuo Yeong Lee1 Nathaniel Zhi-Wei Leon1. Department of Mathematics, Statistics and Computing, NUS High School of Mathematics and Science, 20 Clementi Avenue 1, Singapore 129957, Republic of Singapore ...

  3. Kooli seksuaalhariduse mõjust Eestis / Kai Part, Kai Haldre, Eva Palm ... [jt.

    Index Scriptorium Estoniae

    2011-01-01

    Artikkel on osa UNESCO, Hollandi Radboudi ülikooli ja Tartu Ülikooli koostöös läbi viidud uurimusest, mille eesmärk oli hinnata kooli seksuaalhariduse kulusid ning mõju kuues eri elatustaseme ja geopoliitilise asendiga riigis. Käesolevas artiklis antakse ülevaade Eesti andmetest

  4. Personalikonsultant Kai Kell : ROWE-metoodika loob paindlikkuse / Kai Kell ; interv. Tiina Saar

    Index Scriptorium Estoniae

    Kell, Kai

    2008-01-01

    HR lighthouse OÜ consulting vanemkonsultant tutvustab ROWE (Results only work environment) metoodikat, mis tugineb põhimõttele, et tööd saab hinnata ainult töötulemuste järgi, ning selle rakendamise eeliseid ja puudusi ettevõtetes

  5. Bendrojo lavinimo mokyklos mokinių kiekybinis ir kokybinis mikčiojimo sunkumo įvertinimas

    OpenAIRE

    Januškevičiūtė, Deimantė

    2011-01-01

    Bakalauro darbe analizuojami išoriniai ir vidiniai mikčiojimo požymiai, mokinių požiūrio į mikčiojimą ir emocijų įvertinimo metodikos, mikčiojimo požymių įvertinimo metodikos, analizuojamas mikčiojimo sunkumo laipsnių nustatymas. Suformuluotas tyrimo tikslas, kuriuo buvo siekiama kiekybiškai ir kokybiškai įvertinti mikčiojančių mokinių užsikirtimų dažnumą, pobūdį, įvertinti lydimuosius judesius, remiantis metodiniais Mikčiojimo sunkumo metodikos (SSI) nurodymais ir atskleisti kiekybinio m...

  6. Effects of polysaccharide from Lycium barbarum in alloxan-induced ...

    African Journals Online (AJOL)

    PRECIOUS

    2009-12-01

    8613170662021. (Zhi et al., 2004; Gan et al., 2004; Zhang et al., 2004). LBP have been recently studied for their physiological and pharmaceutical activities. The purpose of this study was to investigate the effect of LBP in alloxan-induced.

  7. Precooling and Warm-Up Effects on Time Trial Cycling During Heat Stress.

    Science.gov (United States)

    Al-Horani, Ramzi A; Wingo, Jonathan E; Ng, Jason; Bishop, Phillip; Richardson, Mark

    2018-02-01

    Heat stress limits endurance exercise performance. Combining precooling and warm-up prior to endurance exercise in the heat may exploit the benefits of both strategies while avoiding the potential negative consequences of each. This study tested the hypothesis that precooling combined with warm-up improves time trial cycling performance in the heat relative to either treatment alone. Nine healthy men completed three 16.1-km time trials in 33°C after: 1) precooling (ice slurry and ice vest) alone (PREC); 2) warm-up alone (WU); or 3) PREC plus WU (COMBO). Tre was lower after PREC compared to WU throughout exercise and lower than COMBO for the first 12 km; COMBO was lower than WU for the first 4 km. Tsk during PREC was lower than COMBO and WU for the first 8 km, and lower in COMBO than WU for the first 4 km. PREC lowered pre-exercise heart rate relative to COMBO and WU (68 ± 10, 106 ± 12, 101 ± 13 bpm, respectively), but it increased similarly during exercise. Local sweat rate (SR) was lower in PREC (0.1 ± 0.1 mg · cm-2 · min-1) than COMBO (0.5 ± 0.2 mg · cm-2 · min-1) and WU (0.6 ± 0.2 mg · cm-2 · min-1) for the first 4 km. Treatments did not differentially affect performance (PREC = 31.9 ± 1.9 min, COMBO = 32.6 ± 2.7 min, WU = 33.1 ± 2.9 min). We conclude precooling alone or with warm-up mitigated thermal strain during exercise, but did not significantly improve 16.1-km cycling time trial performance.Al-horani RA, Wingo JE, Ng J, Bishop P, Richardson M. Precooling and warm-up effects on time trial cycling during heat stress. Aerosp Med Hum Perform. 2018; 89(2):87-93.

  8. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Xing Hui Zhang1 Fu Long Zhang1 Zhi Yuan Geng2. College of Chemical Engineering, Gansu Lianhe University, Lanzhou 730010, P.R. China; College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, P.R. China ...

  9. Li et al., Afr J Tradit Complement Altern Med. (2013) 10(5):375-379 ...

    African Journals Online (AJOL)

    cadewumi

    -gang, Zhao Jin-ning, Wang Zhi, Li Jin. (2004). Effects of Total Flavone from Drynaria Fortunei on Bone. Density and IL-6, IL-4 and TNFα Levels in Ovariectomized Rats. Chinese Journal of Basic Medicine in Traditional Chinese Medicine, 01:.

  10. Los rostros de Ana: Tres comentarios sobre Darío Morales

    Directory of Open Access Journals (Sweden)

    Paul Marcelo Velázquez Sabogal

    2016-03-01

    Full Text Available El presente escrito es una aproximación a la obra del artista colombiano Darío Morales desde la perspectiva dialéctica “vida-muerte”, alentada por el acontecimiento de lo ambiguo y sus implicaciones en la deconstrucción de una corporeidad estable regida por parámetros sociales, jurídicos y biológicos que desembocan en la caracterización de un “otro” en el cual se encuentran figuras como el anormal, el incorregible, el monstruo. Desde ellos pretendo trazar un punto de vista sobre aquellos Rostros de Ana donde se manifiestan figuras como el onanista y la vampira, para desembocar en un comentario que amplíe el espectro de sentido alrededor la obra del artista cartagenero. Palabras claves Cuerpo ambiguo, vida-muerte, sagrado-profano, onanismo. Ñawekuna kai warmi Ana Sutipa: Kimsa pariai ksi runa Dario Morales Sugllapi Kai kilkai kame ñalla regcha kai tacha runa colombiano Dario Morales Kilkakasina rimangapa “ kausai- wamui” aida chingapa kaikuna Mana allilla llugsichu tukuikunamanda icharichu llanga “sug manda” Kaipe turrerreme ¡ kauancheme man aillakaska, man allilla rurasla! Kirú. Kaipi pudenchi kauanga imasami kauacheca kai warme Ana paipa ñawekuna Kai ruraikuna sutikame onanista Chasallata vampira, Kaiwa munakume Allilla intendechengapa imasame parlaku sug iacha Cartagenero. Ima suti Rimai Simi: Cuerpo ambiguo, kaugsai, muerte, sagrado - profano, onanismo. The Faces of Ana: Three Comments on Dario Morales Abstract This paper is an approach to the work of Colombian artist Dario Morales from the perspective of the dialectic of “life and death”, encouraged by the occurrence of the ambiguous and its implications for the deconstruction of a stable corporeality governed by social, legal and biological parameters that lead to the characterization of an “other”, in which figures such as the abnormal, the incorrigible, the monster are to be found. From them, I intend to plot a point of view on those faces of Ana

  11. Polyethylene glycol–polylactic acid nanoparticles modified with cysteine–arginine–glutamic acid–lysine–alanine fibrin-homing peptide for glioblastoma therapy by enhanced retention effect

    Directory of Open Access Journals (Sweden)

    Wu J

    2014-11-01

    Full Text Available Junzhu Wu,1,2,* Jingjing Zhao,1,3,* Bo Zhang,1 Yong Qian,1 Huile Gao,1 Yuan Yu,1 Yan Wei,1 Zhi Yang,1 Xinguo Jiang,1 Zhiqing Pang1 1Key Laboratory of Smart Drug Delivery, Ministry of Education, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, 2School of Pharmacy, Dali University, Xiaguan, 3School of Pharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China *These authors contributed equally to this work Abstract: For a nanoparticulate drug-delivery system, crucial challenges in brain-glioblastoma therapy are its poor penetration and retention in the glioblastoma parenchyma. As a prevailing component in the extracellular matrix of many solid tumors, fibrin plays a critical role in the maintenance of glioblastoma morphology and glioblastoma cell differentiation and proliferation. We developed a new drug-delivery system by conjugating polyethylene glycol–polylactic acid nanoparticles (NPs with cysteine–arginine–glutamic acid–lysine–alanine (CREKA; TNPs, a peptide with special affinity for fibrin, to mediate glioblastoma-homing and prolong NP retention at the tumor site. In vitro binding tests indicated that CREKA significantly enhanced specific binding of NPs with fibrin. In vivo fluorescence imaging of glioblastoma-bearing nude mice, ex vivo brain imaging, and glioblastoma distribution demonstrated that TNPs had higher accumulation and longer retention in the glioblastoma site over unmodified NPs. Furthermore, pharmacodynamic results showed that paclitaxel-loaded TNPs significantly prolonged the median survival time of intracranial U87 glioblastoma-bearing nude mice compared with controls, Taxol, and NPs. These findings suggested that TNPs were able to target the glioblastoma and enhance retention, which is a valuable strategy for tumor therapy. Keywords: CREKA peptide, nanoparticles, retention effect, paclitaxel, glioblastoma

  12. 2K09 and thereafter : the coming era of integrative bioinformatics, systems biology and intelligent computing for functional genomics and personalized medicine research

    Science.gov (United States)

    2010-01-01

    Significant interest exists in establishing synergistic research in bioinformatics, systems biology and intelligent computing. Supported by the United States National Science Foundation (NSF), International Society of Intelligent Biological Medicine (http://www.ISIBM.org), International Journal of Computational Biology and Drug Design (IJCBDD) and International Journal of Functional Informatics and Personalized Medicine, the ISIBM International Joint Conferences on Bioinformatics, Systems Biology and Intelligent Computing (ISIBM IJCBS 2009) attracted more than 300 papers and 400 researchers and medical doctors world-wide. It was the only inter/multidisciplinary conference aimed to promote synergistic research and education in bioinformatics, systems biology and intelligent computing. The conference committee was very grateful for the valuable advice and suggestions from honorary chairs, steering committee members and scientific leaders including Dr. Michael S. Waterman (USC, Member of United States National Academy of Sciences), Dr. Chih-Ming Ho (UCLA, Member of United States National Academy of Engineering and Academician of Academia Sinica), Dr. Wing H. Wong (Stanford, Member of United States National Academy of Sciences), Dr. Ruzena Bajcsy (UC Berkeley, Member of United States National Academy of Engineering and Member of United States Institute of Medicine of the National Academies), Dr. Mary Qu Yang (United States National Institutes of Health and Oak Ridge, DOE), Dr. Andrzej Niemierko (Harvard), Dr. A. Keith Dunker (Indiana), Dr. Brian D. Athey (Michigan), Dr. Weida Tong (FDA, United States Department of Health and Human Services), Dr. Cathy H. Wu (Georgetown), Dr. Dong Xu (Missouri), Drs. Arif Ghafoor and Okan K Ersoy (Purdue), Dr. Mark Borodovsky (Georgia Tech, President of ISIBM), Dr. Hamid R. Arabnia (UGA, Vice-President of ISIBM), and other scientific leaders. The committee presented the 2009 ISIBM Outstanding Achievement Awards to Dr. Joydeep Ghosh (UT

  13. Puerarin transport across rat nasal epithelial cells and the influence of compatibility with paeoniflorin and menthol

    Directory of Open Access Journals (Sweden)

    Zhang L

    2017-09-01

    Full Text Available Lin Zhang, Shou-Ying Du, Yang Lu, Chang Liu, Hui-Chao Wu, Zhi-Hao Tian, Min Wang, Chang Yang School of Chinese Materia Medica, Beijing University of Chinese Medicine, Chaoyang District, Beijing, People’s Republic of China Abstract: Nose-to-brain transport can provide an excellent pathway for drugs of the central nervous system. Consequently, how to make full use of this pathway in practical applications has become a focus of drug design. However, many aspects affecting drug delivery from the nose to the brain remain unclear. This study aimed to more deeply investigate the transport of puerarin and to explore the mechanism underlying the influence of compatible drugs on puerarin permeability in a primary cell model simulating the nasal mucosa. In this research, based on rat nasal epithelial cells (RNECs cultured in vitro and cytotoxicity assays, the bidirectional transport of puerarin across RNEC monolayers and the effect of its compatibility with peoniflorin and menthol were analyzed. The apparent permeability coefficient was <1.5×10–6 cm/s, and the efflux ratio of puerarin was <2, indicating that puerarin had poor absorption and that menthol but not peoniflorin significantly improved puerarin transport. Simultaneously, through experiments, such as immunofluorescence staining, transepithelial electrical resistance measurement, rhodamine 123 efflux evaluation, the cell membrane fluorescence recovery after photobleaching test, and ATPase activity determination, the permeability promoting mechanism of menthol was confirmed to be closely related to disruption of the tight junction protein structure, to the P-glycoprotein inhibitory effect, to increased membrane fluidity, and to the promotion of enzyme activity. These results provide reliable data on nasal administration of the studied drugs and lay the foundation for a deeper investigation of the nose–brain pathway and nasal administration. Keywords: Chinese herbal compound

  14. D : disainialfabeet / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Inglise disainerid Lucienne Day (s. 1917), Robin Day (s. 1915), Tom Dixon (s. 1959) ja ameerika disainer Henry Dreyfuss (1903-1972). Hollandi disainiajakirjast "De Stijl" ja disainirühmitusest "Droog" (asut. 1993)

  15. Experimentadesign Amsterdamis / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2008-01-01

    18.-21. septembrini 2008 toimunud rahvusvahelise disainibiennaali Experimentadesign avanädalast. Biennaali teemaks oli "Space and Place. Design for the Urban Landscape". Näitustest "Sunday Adventure Club" (kuraator Ester van de Wiel), "Droog Event 2 : Urban Play" (kuraator Scott Burnham"), "Come to My Place"

  16. H : disainialfabeet / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Tutvustatakse taani disainerit, arhitekti ja kriitikut Poul Henningseni (1894-1967), austria arhitekti ja disainerit Josef Hoffmanni (1870-1956), belgia arhitekti Victor Hortat (1861-1947), argentiina päritolu disainerit Alfredo Häberlit (sünd. 1964, Buenos Aires), Herman Milleri nimelist mööblitootmisettevõtet (asutatud 1923) USA-s, high-tech stiili

  17. C : disainialfabeet / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Andmeid disainerite kohta: Archille Castiglioni (1918-2002), Antonio Citterio (s. 1950), Luigi Colani (s. 1928), Joe Colombo (1930-1971), Terence Conran (s.1931). Briti disainerite Clare Page (s. 1975) ja Harry Richardsoni (s. 1975) firmast Committee. Cranbrooki kunstiakadeemiast USA-s

  18. Avastatud klaas / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Euroopa kõrgkoolide klaasieriala üliõpilaste tööde näitus "Discovery / Avastusretk" Kullo galeriis kuni 19. V. Rahvusvahelise ürituse korraldajaks oli EKA klaasikunsti osakond eesotsas Mare Saare ja Tiina Sarapuga. Pikemalt Ave Maseri tööst "Maandumine"

  19. V : disainialfabeet / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2007-01-01

    Tutvustatakse Edgar Velbrit arhitektina ja tema poega Teno Velbrit mööblivabriku "Standard" kauaaegse disainerina, Victoria & Alberti Muuesumi Londonis, nimekat mööblitootjat "Vitra", kelle toodangus on palju nimekate disainerite loomingut ja VHUTEMAS'i - kõrgemat kunstikooli 1920. aastail Moskvas

  20. [Textual research on Chen Ye and his Jia cang jing yan fang (Family-preserved Empirical Recipes) of the Song Dynasty].

    Science.gov (United States)

    Zhang, Xuedan; Zhang, Ruqing; Chen, Dexing

    2014-01-01

    Chen Ye, an official of the Southern Song Dynasty, also known as Chen Rihua as his styled name, was born in Changle, Fuzhou in the reign of Shaoxing, and died during the reign of Duanping. He had been consecutively in the positions of Jiang shi lang (Court Gentleman for Ceremonial Service), Zhi zhou (Prefect) of Lingding, the Ti xing (Judicial Commissioner) of Guangdong, the Zong ling (Overseer-general) of Sichuan, Shan ding (Reviser), Shu lin and other positions in Tongzhou, Yuanzhou. His works included 1 volume of Gu ling xian sheng nian pu (Mr. Guling's Chronological Biography), 1 volume of Tan xie (On Humor), 1 volume of Shi hua (Poetry), 8 volumes of Jin yuan li shu (Jin Yuan's Smart Technique), 3 volumes of Yi jian zhi lei bian (Classified Compilation of Yijian's Annals), (Zeng guang) Suo sui lu (Augmented Records of Trivial Matters), 5 volumes of Jia cang jing yan fang (Family-preserved Empirical Recipes). He also compiled the 8-volume Yin jiang zhi (Yinjiang's Annals), published the 2-volume Jia cang ji yao fang (Collected Essential Recipes from Family Preservation), and other proses and poetry. Jia cang jing yan fang was a formulary compiled by Chen Ye, which was lost. Altogether 74 of its recipes were cited in Fu ren da quan liang fang (Complete Effective Prescriptions for Women's Diseases), Shou qin yang lao shu (A Book for Pursuing Seniors' Longevity and Healthcare), Pu ji fang (Prescriptions for Universal Relief) and Yong le da dian (Yongle Encyclopedia).

  1. The efficacy and characteristics of warm-up and re-warm-up practices in soccer players: a systematic review.

    Science.gov (United States)

    Hammami, Amri; Zois, James; Slimani, Maamer; Russel, Mark; Bouhlel, Ezdine

    2018-01-01

    This review aimed 1) to evaluate the current research that examines the efficacy of warm-up (WU) and re-warm-up (RWU) on physical performance; and 2) to highlight the WU and RWU characteristics that optimise subsequent performance in soccer players. A computerized search was performed in the PubMed, ScienceDirect and Google Scholar (from 1995 to December 2015) for English-language, peer-reviewed investigations using the terms "soccer" OR "football" AND "warm-up" OR "stretching" OR "post-activation potentiation" OR "pre-activity" OR "re-warm-up" AND "performance" OR "jump" OR "sprint" OR "running". Twenty seven articles were retrieved. Particularly, 22 articles examined the effects of WU on soccer performance and 5 articles focused on the effects of RWU. Clear evidence exists supporting the inclusion of dynamic stretching or postactivation potentiation-based exercises within a WU as acute performance enhancements were reported (pooled estimate changes of +3.46% and +4.21%, respectively). The FIFA 11+ WU also significantly increases strength, jump, speed and explosive performances (changes from 1% to 20%). At half-time, active RWU protocols including postactivation potentiation practices and multidirectional speed drills attenuate temperature and performance reductions induced by habitual practice. The data obtained in the present review showed that the level of play did not moderate the effectiveness of WU and RWU on soccer performance. This review demonstrated that a static stretching WU reduced acute subsequent performance, while WU activities that include dynamic stretching, PAP-based exercises, and the FIFA 11+ can elicit positive effects in soccer players. The efficacy of an active RWU during half-time is also justified.

  2. Simultaneous determination of bioactive components in essential oil of Xiang-Fu-Si-Wu Formula in Beagle dog plasma by UPLC-MS/MS and its application to pharmacokinetics.

    Science.gov (United States)

    Liu, Pei; Li, Zhenhao; Qian, Dawei; Li, Wei; Shang, Er-Xin; Duan, Jin-Ao

    2013-06-15

    A highly sensitive and rapid ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) has been developed and validated for simultaneous quantification of the three main bioactive compounds, i.e., ligustilide, dehydrocostuslactone and α-cyperone in dog plasma after oral administration of the essential oil of Xiang-Fu-Si-Wu Formula (XEO). Clarithromycin was used as an internal standard (IS). Plasma samples were processed by protein precipitation with methanol. The separation was performed on an Acquity BEH C18 column (100mm×2.1mm, 1.7μm) at a flow rate of 0.4mLmin(-1), using 0.1% formic acid-acetonitrile as mobile phase. The MS/MS ion transit ions monitored were 190.5→90.9 for ligustilide, 231.1→185.1 for dehydrocostuslactone, 219.2→123.0 for α-cyperone and 748.5→158.1 for IS. Method validation was performed as per Food and Drug Administration guidelines and the results met the acceptance criteria. The lower limit of quantification (LLOQ) achieved was 5.12ng/mL for ligustilide, 1.06ng/mL for dehydrocostuslactone and 1.89ng/mL for α-cyperone, respectively, and the calibration curves obtained were linear (r>0.99) over the concentration range approximately 1-1000ng/mL. The intra- and inter-day precision was less than 15% and the accuracy was within ±9.2%. After validation, this method was successfully applied to a pharmacokinetic study where dogs were orally given 0.3g/kg XEO, equivalent to 183.6mg/kg of ligustilide, 5.0mg/kg of dehydrocostuslactone and 26.2mg/kg of α-cyperone, respectively. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. Person-environment fit: using commensurate scales to predict student stress.

    Science.gov (United States)

    Puccio, G J; Talbot, R J; Joniak, A J

    1993-11-01

    The relationship between person-environment fit and stress was examined for two samples of university students (N = 55 and 79). The Kirton Adaption-Innovation Inventory (KAI) was modified to assess the students' perceptions of the adaptor-innovator style required by their course, the styles they exhibited in the course, and their ideal style preferences. To ascertain fit, the KAI total scores and subscale scores (Originality, Efficiency, and Rule/Group Conformity) were used to classify students on three dimensions: (1) perception of what style their course required, adaptive or innovative; (2) congruence between the style the course required and the style they exhibited in the course; and (3) the magnitude of the difference, if any, between the required style and the exhibited style. Points two and three are measures of fit. The dependent variable was stress. Also the students' ideal style scores, KAI total and subscales, were substituted for the exhibited scores and the classification and analyses were repeated. Analysis of the total scores revealed that a course requiring adaptive behaviours was perceived as more stressful than a course requiring innovative behaviours. Similarly, an analysis of the Rule/Group Conformity scores revealed that the greater the conformity required the greater the stress. Also the less originality demanded in the course the greater was the perceived stress. For the KAI total scores and Rule/Group Conformity scores, the two measures of fit (incongruity and magnitude of the incongruity) were not related to stress. However, analyses of the Originality and Efficiency subscales supported the importance of the P-E fit position. For both subscales, stress was associated with the magnitude of the difference between what was required in the course and what students exhibited in the course. Educational implications derived from these findings as well as recommendations for future research are discussed.

  4. A Review on Gnetalean Megafossils: Problems and Perspectives

    Directory of Open Access Journals (Sweden)

    Yong Yang

    2010-11-01

    Full Text Available Gnetalean megafossils were accumulated in the last decade. Taxonomic positions of several of Ephedran megafossil species are, however, controversial, resulting in a complicated nomenclature. Liaoxia Z.Y. Cao & S.Q. Wu, “Eragrostis Z.Y. Cao & S.Q. Wu”, “Chaoyangia Duan”, and their type species “Liaoxia cheniae Z.Y. Cao & S.Q. Wu”, “Eragrostis changii Z.Y. Cao & S.Q. Wu”, “Chaoyangia liangii S.Y. Duan”, were not validly published in the original publication under the Vienna Code. The species “Liaoxia cheniae Z.Y. Cao & S.Q. Wu” was validly published as Ephedrites cheniae S.X. Guo & X.W. Wu but later combined into Liaoxia cheniae (S.X. Guo & X.W. Wu Z.Y. Cao & S.Q. Wu and further into Ephedra cheniae (S.X. Guo & X.W. Wu H.M. Liu et al. Some uncertain morphological characters are fundamental to elucidate the taxonomic position of Ephedrites cheniae S.X. Guo & X.W. Wu and “Chaoyangia liangii S.Y. Duan”, e.g. bract number, position, and connation in female cones, seed number and position in a female cone, and morphology of the furcated appendages of reproductive organs of “Chaoyangia liangii S.Y. Duan”.

  5. Can commercial surrogacy be equated to human trafficking?

    OpenAIRE

    Monstytė, Evelina

    2014-01-01

    Surogaciją būtų galima įvardinti viena iš seniausių prekybos žmonėmis, taip pat ir vaikais, formų. Nors dauguma žmonių mano, jog surogacija yra medicinos naujovė, iš tikro šis būdas buvo žinomas dar Biblijos laikais.Didžiausias lūžis medicinoje, po kurio surogacija tapo plačiai naudojama procedūra, įvyko 1978 m. liepos 25 dieną, kai gimė pirmasis kūdikis, kuris buvo pradėtas mėgintuvėlyje. Ši technologija suteikė galimybę nevaisingoms poroms susilaukti genetiškai su jais susijusio vaiko. Taip...

  6. People’s Republic of China Scientific Abstracts No. 178

    Science.gov (United States)

    1977-10-27

    of hepatic colls were observed by eleotron microscopy after carbon tetrachloride intoxication in mice . The hepatic cellular injuries were protected...administration in [continuation of SHENG-WU HUA-HSUEH YU SHENG-WU WU-LI-HSUEH-PAO Vol 8, No A, Dec 76 pp 333-340] mice . It is transformed from lipid...preparations for monopolizing the technique by capi- talist and revisionist countries. In a socialist country, the author claims, the purpose of developing

  7. Comparison of the effects of active, passive and mixed warm ups on swimming performance.

    Science.gov (United States)

    Adams, S; Psycharakis, S G

    2014-10-01

    The aim of this paper was to compare the effects of an active (AWU), passive (PWU) and mixed warm up (MWU) on swimming performance. Eight male competitive swimmers completed each type of WU and, following a 20-minute rest, performed a maximum 100m test on their specialised stroke. The order of WUs was randomized and there was a 7-day period between subsequent testing sessions. The time taken to complete the 100m trial was the performance measure. The rating of perceived exertion (RPE) was measured immediately post WU, while heart rate (HR) was measured pre and post WU and pre and post the maximum swim. During the 20-minute rest, the swimmers' psychological state was assessed with the CSAI-2 questionnaire. Post WU HR and RPE had the lowest values following the AWU and the highest values following the PWU (Pperformance HR increased significantly relative to pre WU HR for all conditions (P≤0.01). Swimmers had relatively low levels of anxiety and modest to high levels of self confidence for all conditions. No WU appeared to be superior to the others with respect to swimming performance. The MWU produced nearly identical values to the AWU for most variables, and was therefore found to be an appropriate alternative WU type that swimmers may use before competition. The PWU also seemed to be appropriate, but the somewhat worse performance and lower cognitive anxiety and self confidence scores recorded, albeit non-significant, suggested that more swimmers and distances are tested before any firm conclusions regarding its effectiveness can be drawn.

  8. Effects of general, specific and combined warm-up on explosive muscular performance

    Directory of Open Access Journals (Sweden)

    David Cristobal Andrade

    2015-02-01

    Full Text Available The purpose of this study was to compare the acute effects of general, specific and combined warm-up (WU on explosive performance. Healthy male (n=10 subjects participated in six WU protocols in a crossover randomized study design. Protocols were: passive rest (PR; 15 min of passive rest, running (Run; 5 min of running at 70% of maximum heart rate, stretching (STR; 5 min of static stretching exercise, jumping [Jump; 5 min of jumping exercises – 3x8 countermovement jumps (CMJ and 3x8 drop jumps from 60 cm (DJ60], and combined (COM; protocols Run + STR + Jump combined. Immediately before and after each WU, subjects were assessed for explosive concentric-only (i.e. squat jump – SJ, slow stretch-shortening cycle (i.e. CMJ, fast stretch-shortening cycle (i.e. DJ60 and contact time (CT muscle performance. PR significantly reduced SJ performance (p =0.007. Run increased SJ (p =0.0001 and CMJ (p =0.002. STR increased CMJ (p =0.048. Specific WU (i.e. Jump increased SJ (p =0.001, CMJ (p =0.028 and DJ60 (p =0.006 performance. COM increased CMJ performance (p =0.006. Jump was superior in SJ performance vs. PR (p =0.001. Jump reduced (p =0.03 CT in DJ60. In conclusion, general, specific and combined WU increase slow stretch-shortening cycle (SSC muscle performance, but only specific WU increases fast SSC muscle performance. Therefore, to increase fast SSC performance, specific fast SSC muscle actions must be included during the WU.

  9. African Journal of Biotechnology - Vol 5, No 11 (2006)

    African Journals Online (AJOL)

    Seperation, identification and analysis of pigment (melanin) production in Streptomyces · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. SG Dastager, WJ Li, A Dayanand, S-K Tang, X-P Tian, X-Y Zhi, L-H Xu, C-L Jiang ...

  10. People’s Republic of China Scientific Abstracts, Number 177

    Science.gov (United States)

    1977-10-06

    PAO [ARCHITECTURAL JOURNAL] No 2, June 1977 1 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 4, December 1976 13 CHIH-WU TSA-CHIH [JOURNAL OF BOTANY...10424 CSO: 4009 12 ACTA BOTANICA SINICA AUTHOR: None ORG: Three-in-one Combination Experimental Group of Peking Ch’ung-wen Vegetable Station...Physiological Processes of Stored Tomatoes" SOURCE: Peking CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] in Chinese Vol 18, No 4, Dec 76 pp 278-283 TEXT OF

  11. Segadus ravimite hinna ümber / Piret Sell

    Index Scriptorium Estoniae

    Sell, Piret

    2005-01-01

    Oma vastulauses 12. detsembri Eesti Päevalehes ilmunud Kai Kalamehe artiklile "Mitmete ravimite hind tõuseb" selgitab autor ravimite hinnatõusu ning seda, miks on originaalravimid kallimad kui koopiaravimid

  12. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Journal of Astrophysics and Astronomy. JOAA-D-15-00122. Power spectrum density of stochastic oscillating accretion disk. G. B. Long, J. W. Ou and Y. G. Zheng. JOAA-D-15-00124. Stochastic oscillations of general relativistic disks described by a fractional Langevin equation with fractional Gaussian noise. Wang Zhi-Yun ...

  13. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Astrophysics and Astronomy; Volume 37; Issue 2. Issue front cover thumbnail. Volume 37, Issue 2. June 2016. Article ID 8. Stochastic Oscillations of General Relativistic Disks Described by a Fractional Langevin Equation with Fractional Gaussian Noise · Wang Zhi-Yun Chen Pei-Jie · More Details ...

  14. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 122; Issue 6. Synthesis and aggregation study of optically active tetra--[()-2-octanyloxy]-substituted copper and nickel phthalocyanines. Fang-Di Cong Gui Gao Jian-Xin Li Guo-Qing Huang Zhen Wei Feng-Yang Yu Xi-Guang Du Ke-Zhi Xing. Full Papers Volume ...

  15. Connections between the Radio, Optical and Soft X-ray Luminosities ...

    Indian Academy of Sciences (India)

    for Flat-Spectrum Radio Quasars. Zhi-Fu Chen1, Cai-Juan Pan1,∗, You-Bing Li2 & Yu-Tao Zhou3. 1Department of Physics and Telecommunication Engineering of Baise University,. Baise 533000, China. 2Guangzhou City Construction College, Guangdong 510925, China. 3Center for Astrophysics, Guangzhou University, ...

  16. Photodetachment cross-section of in a three-dimensional cubical ...

    Indian Academy of Sciences (India)

    DE-HUA WANG

    2017-10-19

    Oct 19, 2017 ... DE-HUA WANG. ∗. , PANG-ZHI .... on the surfaces along x, y, z directions, respectively. Then the ..... [20] Y Han, L F Wang, S Y Ran and G C Yang, Physica B. 405, 3082 ... [36] D H Wang, Y J Yu and S L Lin, Chin. Opt. Lett.

  17. The effects of three different grinding methods in DNA extraction of ...

    African Journals Online (AJOL)

    uwerhiavwe

    2013-04-17

    Apr 17, 2013 ... The effects of three different grinding methods in DNA extraction of cowpea .... 100 mg of the leaf tissues were weighed in an electronic balance. CTAB method .... The primers were synthesized by Life Technologies (AB & Invitrogen). .... This work was supported by 'Shuang-Zhi Plan' of Sichuan. Agricultural ...

  18. Jiang et al., Afr J Tradit Complement Altern Med. (2015) 12(S):45-51 ...

    African Journals Online (AJOL)

    Background: To explore the effects of Zhi-Bai-Di-Huang-Wan (ZBDHW), a classic formula of Chinese medicinal herbs in relieving menopausal symptoms in British and Chinese women. Methods and Materials: Between May 2011 and May 2013, 224 Chinese and British women were divided into a ZBDHW group with 115.

  19. An inductive narrow-pulse RFID telemetry system for gastric slow waves monitoring.

    Science.gov (United States)

    Javan-Khoskholgh, Amir; Abukhalaf, Zaid; Ji Li; Miller, Larry S; Kiani, Mehdi; Farajidavar, Aydin

    2016-08-01

    We present a passive data telemetry system for real-time monitoring of gastric electrical activity of a living subject. The system is composed of three subsystems: an implantable unit (IU), a wearable unit (WU), and a stationary unit (SU). Data communication between the IU and WU is based on a radio-frequency identification (RFID) link operating at 13.56 MHz. Since wireless power transmission and reverse data telemetry system share the same inductive interface, a load shift keying (LSK)-based differential pulse position (DPP) coding data communication with only 6.25% duty cycle is developed to guarantee consistent wireless downlink power transmission and uplink high data transfer rate, simultaneously. The clock and data are encoded into one signal by an MSP430 microcontroller (MCU) at the IU side. This signal is sent to the WU through the inductive link, where decoded by an MSP432 MCU. Finally, the retrieved data at the WU are transmitted to the SU connected to a PC via a 2.4 GHz transceiver for real-time display and analysis. The results of the measurements on the implemented test bench, demonstrate IU-WU 125 kb/s and WU-SU 2 Mb/s data transmission rate with no observed mismatch, while the data stream was randomly generated, and matching between the transmitted data by the IU and received by the SU verified by a custom-made automated software.

  20. Performance-intensity functions of Mandarin word recognition tests in noise: test dialect and listener language effects.

    Science.gov (United States)

    Liu, Danzheng; Shi, Lu-Feng

    2013-06-01

    This study established the performance-intensity function for Beijing and Taiwan Mandarin bisyllabic word recognition tests in noise in native speakers of Wu Chinese. Effects of the test dialect and listeners' first language on psychometric variables (i.e., slope and 50%-correct threshold) were analyzed. Thirty-two normal-hearing Wu-speaking adults who used Mandarin since early childhood were compared to 16 native Mandarin-speaking adults. Both Beijing and Taiwan bisyllabic word recognition tests were presented at 8 signal-to-noise ratios (SNRs) in 4-dB steps (-12 dB to +16 dB). At each SNR, a half list (25 words) was presented in speech-spectrum noise to listeners' right ear. The order of the test, SNR, and half list was randomized across listeners. Listeners responded orally and in writing. Overall, the Wu-speaking listeners performed comparably to the Mandarin-speaking listeners on both tests. Compared to the Taiwan test, the Beijing test yielded a significantly lower threshold for both the Mandarin- and Wu-speaking listeners, as well as a significantly steeper slope for the Wu-speaking listeners. Both Mandarin tests can be used to evaluate Wu-speaking listeners. Of the 2, the Taiwan Mandarin test results in more comparable functions across listener groups. Differences in the performance-intensity function between listener groups and between tests indicate a first language and dialectal effect, respectively.

  1. Kaisi kimbutav õlavalu sundis eestlasi turniiri katkestama / Ann Hiiemaa

    Index Scriptorium Estoniae

    Hiiemaa, Ann

    2007-01-01

    Nädal tagasi maailmameistrivõistlustelt viienda koha rannavõrkpallurid Kristjan Kais ja Rivo Vesik olid Kaisi õlavalu tõttu sunnitud Austrias Klagenfurtis toimuva Grand Slami etapi pooleli jätma

  2. Augalų, auginamų žaliajai trąšai, agrobiologinis įvertinimas ir įtaka svogūnų derliui

    OpenAIRE

    Starkutė, Roma; Duchovskienė, Laisvūnė; Zalatorius, Zytautas

    2006-01-01

    2003–2005 m. Lietuvos sodininkystės daržininkystės institute ekologiškai daržovėms auginti skirtame bandymų lauke tirti ir įvertinti žaliajai trąšai tinkamiausi augalai ir nustatyta jų įtaka ekologiškai auginamų svogūnų derliui. Tirti augalai žaliajai trąšai: miežiai, miežiai su dobilų įsėliu, vasariniai kviečiai, žirnių ir avižų mišinys, aliejiniai ridikai. Kontrolinis variantas – juodasis pūdymas. Nustatyta, kad žaliajai trąšai auginamų augalų biomasė armenyje paliko nevienodą organinės med...

  3. 对格里埃尔《声乐协奏曲》的两种演唱诠释---吴碧霞与德赛演唱的《声乐协奏曲》之比较%Interpretation of Two Types of Singing Performance of Gliere's"Vocal Concerto":A Comparison of"Vocal Con-certo"Sung by Wu Bixia and Natalie Dessay

    Institute of Scientific and Technical Information of China (English)

    张艳

    2015-01-01

    吴碧霞被誉为“中西合璧”的夜莺,无论在美声唱法还是民族唱法领域都有一定的造诣,演唱的歌曲都有丰富的表现力与感染力。纳塔利·德赛同样也被誉为20世纪末的“声音奇迹”,两个来自不同国度的歌唱家在演绎这首《声乐协奏曲》时,也有着不同的演唱风格与音响效果。通过对吴碧霞与德赛演唱的这首《声乐协奏曲》的比较分析,让我们更加清楚地认识到我国声乐发展的前景,并对两种风格的演唱进行文化的理解与思考。%Wu Bixia is hailed as a "nightingale" integrating the East and the West, as she has certain attainments in both bel canto and nazionale cantanti, and the songs sung by her are all highly expressive and attractive. Natalie Dessay is honored as a"vocal marvel" at the end of the 20th century. The two singers from two different countries have different singing styles and vo-cal effects when they sing"Vocal Concerto". Through a compara-tive analysis on"Vocal Concerto"sung by Wu Bixia and Natalie Dessay, we can more clearly learn about the prospect of the de-velopment of vocal music in China, thus understanding and re-flecting more about the cultures of the two styles.

  4. Upregulation of miR-222 in both Helicobacter pylori-infected and ...

    Indian Academy of Sciences (India)

    MINA NOORMOHAMMAD

    of this study was to analyse the expression level of miR-222 in gastric cancer tissues, evaluating the relationship between. miR-222 ... using RT-qPCR and compared with 88 healthy samples. ... observed in some diseases; for instance, hepatocellular carci- noma .... cellular matrix proteins in stomach cells (Chun-Zhi et al.

  5. Molecular characters and expression analysis of a new isoform of ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-10-20

    Oct 20, 2008 ... isoform of the myocyte enhancer factor 2 gene from the silkworm, Bombyx mori. Qing-zhi Ling1, 2, ... BMEF2B mRNA content in the brain was measured using the combined method of quantitative RT-PCR and Southern ... specific cofactors to control gene expression in pheno- typically different muscles.

  6. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Schinzel–Giedion syndrome: a novel case, review and revised diagnostic criteria · WEI-LIANG LIU ZHI-XU HE FANG LI RONG AI HONG-WEI MA · More Details Abstract Fulltext PDF. Schinzel–Giedion syndrome (SGS) is a rare autosomal dominant inheritance disorder. Heterozygous de novo mutations in the SETBP1 gene ...

  7. Vanemuislaste ballett astub uude kümnesse / Raimu Hanson

    Index Scriptorium Estoniae

    Hanson, Raimu, 1957-

    2009-01-01

    Vanemuise balleti ajaloost, 4. märtsil 1939. aastal toimunud esietendusest, tänasest teatri balletitrupist. Juubeliks ilmunud raamatust ja DVD-st "Vanemuise ballett 70", koostajad Mare Tommingas ja Kai Kangur

  8. Pateetiline kukkumine XXI sajandisse / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2000-01-01

    Tartu Kunstimajas ja monumentaalgaleriis avatud Reet Varblase kureeritud näitusest "Eneseksjäämine. Väikesed rollimängud XXI sajandiks". Pikemalt Terje Ojaveri performance'ist, Kai Kaljo videost "Pateetika"

  9. The Role of Retinal Determination Gene Network (RDGN) in Hormone Signaling Transduction and Prostate Tumorigenesis

    Science.gov (United States)

    2013-10-01

    Wu K, Wang L, Jiao X, Ju X, Li Z, Ertel A, Addya S, McCue P, Lisanti MP, Wang C, Davis RJ, Mardon G, Pestell RG. Androgen therapy resistant...Li Z, Hu J, Chen K, Wu J, Pestell RG. DACH1 inhibited prostate cancer cellular proliferation and Interleukon-6 signaling. AACR 103rd Annual Meeting...March 31 – April 4, 2012, Chicago, IL.  Wang J, Cai S, Chen K, Sun Y, Li S, Pestell RG, Wu K. Regulation of AR transcriptional activity and

  10. Eesti ajalugu Vene-Liivimaa sõjast Põhjasõjani / Lea Kõiv

    Index Scriptorium Estoniae

    Kõiv, Lea, 1961-

    2014-01-01

    Arvustus: Enn Küng, Margus Laidre, Ivar Leimus, Aivar Põldvee, Anti Selart, Marten Seppel, Kai Tafenau, Ülle Tarkiainen, Enn Tarvel. Eesti ajalugu III: Vene-Liivimaa sõjast Põhjasõjani. Tartu, 2013

  11. Kultuurkapitali preemiad

    Index Scriptorium Estoniae

    2000-01-01

    Eesti Kultuurkapitali aastapreemia U. Lippusele, Helikunsti aastapreemiad J. Leitenile, M. Martinile, J. Reinverele, V. Sarvele, A. Volmerile, Uus Tallinna Triole, Duole Kai Ratassepp, Mati Mikali; Rahvakultuuri Sihtkapitali aastapreemia J. Rent, V. Sarv

  12. Avatud arhiiv / Ketli Tiitsar

    Index Scriptorium Estoniae

    Tiitsar, Ketli

    2005-01-01

    Näitus "Arhiiv. Tarbekunstimuuseumi näitused 1982-2004" Eesti Tarbekunsti- ja Disainimuuseumis kuni 15. I 2006. Näituse on koostanud Merike Alber, Kai Lobjakas, Airi Ligi, Anne Tiivel, kujundanud Ketli Tiitsar

  13. Baltikumi meediakunst Dortmundis / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-

    2006-01-01

    Balti kultuurifestivalist "scene: estland lettland litauen in nrw" Dortmundi Ostwall-muuseumis. Eestit esindavad oma töödega Kai Kaljo, Mark Raidpere, Jaan Toomik, Tiia Johannson, Killu Sukmit, Mari Laanemets, Raivo Kelomees

  14. Acute and Time-Course Effects of Traditional and Dynamic Warm-Up Routines in Young Elite Junior Tennis Players.

    Directory of Open Access Journals (Sweden)

    Francisco Ayala

    Full Text Available Despite the large number of studies that have examined the acute effects of different warm up modalities (WU on physical performance, none of them have documented the time course of potential performance recovery in tennis players. The aim of this study was twofold: (a to analyze and compare the acute effects of two different WU modalities (traditional WU [TWU] and dynamic WU [DWU] on physical performance (i.e., CMJ, sprint, serve speed and accuracy in elite junior players, as well as (b to monitor the time course of any WU-induced changes after 30 and 60 min of simulated match-play. Twelve junior elite players completed both WUs modalities (TWU and DWU in a counterbalanced order on separate days. In each experimental session, counter movement jump (CMJ, 20-m sprint, tennis serve speed and accuracy tests were performed before (immediately after TWU or DWU during (30 min and after 60 min of a simulated match play. Measures were compared via four factorial (WU intervention and time repeated measures ANOVAs. There were main effects of WU (TWU and DWU throughout the time for all the variables analysed. The results indicate that DWU routine led to significantly faster 20 m sprint times and higher CMJs as well as faster and more accurate tennis serves at both post warm-up and 30 min match-play testing moments in comparison with the scores reported by the TWU routine (p 75-99%. No significant intergroup differences were found at 60-min match-play testing moment in any variable (except for the 20 m sprint. Therefore, the findings of this study recommend for optimal performance in these elite tennis players, DWU routines should be performed prior to formal training and competition rather than TWU routines.

  15. Uncertainty of Wheat Water Use: Simulated Patterns and Sensitivity to Temperature and CO2

    Science.gov (United States)

    Cammarano, Davide; Roetter, Reimund P.; Asseng, Senthold; Ewert, Frank; Wallach, Daniel; Martre, Pierre; Hatfield, Jerry L.; Jones, James W.; Rosenzweig, Cynthia E.; Ruane, Alex C.; hide

    2016-01-01

    Projected global warming and population growth will reduce future water availability for agriculture. Thus, it is essential to increase the efficiency in using water to ensure crop productivity. Quantifying crop water use (WU; i.e. actual evapotranspiration) is a critical step towards this goal. Here, sixteen wheat simulation models were used to quantify sources of model uncertainty and to estimate the relative changes and variability between models for simulated WU, water use efficiency (WUE, WU per unit of grain dry mass produced), transpiration efficiency (Teff, transpiration per kg of unit of grain yield dry mass produced), grain yield, crop transpiration and soil evaporation at increased temperatures and elevated atmospheric carbon dioxide concentrations ([CO2]). The greatest uncertainty in simulating water use, potential evapotranspiration, crop transpiration and soil evaporation was due to differences in how crop transpiration was modelled and accounted for 50 of the total variability among models. The simulation results for the sensitivity to temperature indicated that crop WU will decline with increasing temperature due to reduced growing seasons. The uncertainties in simulated crop WU, and in particularly due to uncertainties in simulating crop transpiration, were greater under conditions of increased temperatures and with high temperatures in combination with elevated atmospheric [CO2] concentrations. Hence the simulation of crop WU, and in particularly crop transpiration under higher temperature, needs to be improved and evaluated with field measurements before models can be used to simulate climate change impacts on future crop water demand.

  16. Women in physics

    CERN Document Server

    Indovino, Shaina

    2013-01-01

    What does it take to be a physicist? Lise Meitner, Katharine Blodgett, Maria Goeppert-Mayer, Chien-Shiung Wu, Ursula Franklin, Argelia Velez-Rodriguez, Sau Lan Wu, Shirley Ann Jackson, Lisa Randall and opportunities for women in physics today.

  17. Differential expression patterns of metastasis suppressor proteins in basal cell carcinoma.

    Science.gov (United States)

    Bozdogan, Onder; Yulug, Isik G; Vargel, Ibrahim; Cavusoglu, Tarik; Karabulut, Ayse A; Karahan, Gurbet; Sayar, Nilufer

    2015-08-01

    Basal cell carcinomas (BCCs) are common malignant skin tumors. Despite having a significant invasion capacity, they metastasize only rarely. Our aim in this study was to detect the expression patterns of the NM23-H1, NDRG1, E-cadherin, RHOGDI2, CD82/KAI1, MKK4, and AKAP12 metastasis suppressor proteins in BCCs. A total of 96 BCC and 10 normal skin samples were included for the immunohistochemical study. Eleven frozen BCC samples were also studied by quantitative real time polymerase chain reaction (qRT-PCR) to detect the gene expression profile. NM23-H1 was strongly and diffusely expressed in all types of BCC. Significant cytoplasmic expression of NDRG1 and E-cadherin was also detected. However, AKAP12 and CD82/KAI1 expression was significantly decreased. The expressions of the other proteins were somewhere between the two extremes. Similarly, qRT-PCR analysis showed down-regulation of AKAP12 and up-regulation of NM23-H1 and NDRG1 in BCC. Morphologically aggressive BCCs showed significantly higher cytoplasmic NDRG1 expression scores and lower CD82/KAI1 scores than non-aggressive BCCs. The relatively preserved levels of NM23-H1, NDRG1, and E-cadherin proteins may have a positive effect on the non-metastasizing features of these tumors. © 2014 The International Society of Dermatology.

  18. Electromagnetic properties of low-spin states in 102,104Pd

    International Nuclear Information System (INIS)

    Luontama, M.; Julin, R.; Kantele, J.; Passoja, A.; Trzaska, W.; Baecklin, A.; Jonsson, N.G.; Westerberg, L.

    1985-12-01

    Electromagnetic transitions from low-lying 0 + , 2 + , 4 + and 3 - states in 102 , 104 Pd have been studied with (p,2n) and (p,p) reactions and with Coulomb excitation. The E2 transition probabilities from the 0 3 + state in 102 Pd (13 W.u.) and from the 0 2 + state in 104 Pd (14 W.u.) are somewhat low for two-phonon states. Generally, the E2 transition rates are reasonably well reproduced by the IBA-2 and by the boson-expansion description. The intruding 0 2 + state (tsub(1/2) = 14.3 ns) in 102 Pd is connected to the 2 2 + and 2 3 + states via strong E2 transitions: B(E2;0 2 + →2 2 + )=96+-40 W.u.; B(E2;2 3 + →0 2 + )=17+-8 W.u

  19. Building for the Future: China’s Progress in Space Technology During the Tenth 5-Year Plan and the U.S. Response

    Science.gov (United States)

    2008-03-01

    Navigation System,” Science and Global Security, December 2004, pp. 219-250. 68. Kang Guohua, Liu Jianye, Zhu Yanhua, and Xiong Zhi, “GPS/SST/SINS zuhe...73. Xie Tao, “‘Shen liu’ shenkong fangda ‘hangtian jingji ’” (“‘Shenzhou’ VI Amplifies the ‘Space Economy’”), Zhongguo Hangtian (Aerospace China

  20. Fulltext PDF

    Indian Academy of Sciences (India)

    YIMING LU1,3, PING HE2,∗, SHU-HUA MA3, GUO-ZHI LI4 and. SALEH MOBAYBEN1. 1Laboratory of Train Network, Department of Train Control Tech., Research Center of Product. & Tech., CRRC TANGSHAN CO., LTD, No. 3, Changqian Rd, Fengrun DIST, Tangshan,. Hebei, 063035, People's Republic of China. 2School ...

  1. Auriga kaubanduskeskus Saaremaal = Auriga shopping centre, Saaremaa

    Index Scriptorium Estoniae

    2009-01-01

    Saaremaal Kudjape külas Tallinna t. 88 asuva Auriga kaubanduskeskuse sisekujundusest. Sisearhitektid Liina Saabas ja Kai Laanmets. Arhitekt Eero Palm. Sisearhitektide tähtsamate ühiselt tehtud tööde loetelu

  2. Tartu Keskkonnahariduse Keskuse Loodusmaja = Nature School of Tartu Environmental Education Centre

    Index Scriptorium Estoniae

    2015-01-01

    Tartu Keskkonnahariduse Keskuse Loodusmaja Lille tänav 10, valminud 2013. Arhitektuurivõistlus 2010. Arhitektid Martin Kinks, Risto Parve, Kai Süda, Margit Valma (Karisma Arhitktid), Diana Taalfeld (NU Arhitektuur). Sisearhitekt Tõnis Kalve

  3. President 2001 / interv. Kai Kalamees

    Index Scriptorium Estoniae

    2001-01-01

    Eesti Päevaleht palus erinevate elualade esindajatel hinnata presidendikandidaatide ametisse sobivust (Savi, Tarand, Kelam, Kreitzberg, Tulviste). Vastavad: Aivar Voog, Rein Ruutsoo, Kaur Hanson, Ivo Rull, Tarmo Tammerk, Mart Helme, Pavel Ivanov, Jaan Kaplinski. Diagrammid

  4. Vormistatud ruumid 2010 / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2011-01-01

    Eesti Sisearhitektide Liidu 2010. a. preemia saanud töödest. Söögikoha interjööri preemia: kohvik Supelsaksad Pärnus (Ruth, Jaak ja Anna Huimerind), ühiskondliku interjööri preemia: ADM Interactive'i büroo Tallinnas (Tomomi Hayashi, Ahti Grünberg, Kerli Valk), ajaloolise interjööri preemia: Kihnu muuseum (Malle Jürgenson, Tea Tammelaan, Krista Lepland, Jaak Huimerind, Indrek Laos), näituse- ja installatsiooni kujunduse preemia: rändnäitus "Eesti kirjanik karikatuuris" (Janno Siimar, Kaarel Vahtramäe, Mart Lankots, Liina Jakobson), tudengipreemia - Aet Tera

  5. Ujuv restoran Portos / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    1999-01-01

    Tegu on terasest ja kolmest küljest klaasist kuubikuga, mis asetseb ankrus olevale ujuvalusele paigutatud puitplatvormil Duoro jõel. Kaldast on restoran eraldatud puitseintega, mille ees olev metalltala toetab katust. Autor G. P. Couto.

  6. Jõulujazz alustab heaga / Kai Ilustrumm

    Index Scriptorium Estoniae

    Ilustrumm, Kai

    2004-01-01

    Heategevuskontserdist "Aita alustada elu!" Kaarli kirikus 28. nov., Soome multiinstrumentalisti Sakari Kukko trio kontserdist 5. dets. Niguliste muuseum-kontserdisaalis, ameerika vokaalansambli M-Pact kontserdist 7. dets. Pärnu kontserdimajas, Raivo Tafenau-Meelis Vindi koosmusitseerimisest tšiili löökpillimängija Ricardo Padillaga 11. dets. Niguliste muuseum-kontserisaalis, Helin-Mari Arderi kontserdist "Sajab esimest lund" 15. dets. Niguliste muuseum-kontserisaalis, rootsi ansambli Bossa Electrica esinemiset 16. dets. Rock Café's, ansambli Eesti Keeled kontserdist "Vaiksel ööl" 17. dets. Tallinnas Sokos Hotell Virus

  7. Kindluselamud Lebbekes, Belgias / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    1999-01-01

    Sotsiaalehitistena tellitud Lebbeke neli uut maja näevad välja nagu hästikindlustatud eramud. 1,7 meetri kõrguste tellismüüridega suletud alade sees asuvad autovarjualune, aiakuur, terrass ja aed, mis on klaasseina abi ühenduses maja alumise korrusega. Materjalid: tellis, tumehall metall, betoon. Autor: Bob 361 Arhitektid.

  8. R : disaini alfabeet / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2007-01-01

    Tutvustatakse Ameerika graafilise disaini euroopalikumaks muutjat Paul Rand'i, sisearhitekti Toivo Raidmetsa, rahvusvahelise taustaga disainerit Karim Rashid'i, keraamikut ja pedagoogi Leo Rohlinit ja kunsti radikaalseks uuendamiseks asutatud rühmituse (1917.a.) De Stijl üht hilisemat liiget Gerrit Rietveldi

  9. Eesti disaini uudised / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Eesti Kunstiakadeemia üliõpilaste Kadri Kruus-Laurimaa kott-jope, Riho Tiiveli lusikas "Spoon container" ja Ülle Jehe sisustuspadjad "Roll it!" valiti Prantsusmaal toimunud rahvusvahelisel kunsti-ja disainikõrgkoolide võrgustiku CUMULUS konkursil "European Ways of Life" nominentide hulka. EKA sisearhitektuuri eriala üliõpilaste toolide hindamisest. Mari Adamsoni nimelise noore tekstiilikunstniku preemia pälvis Kadri Klampe. Eesti Ajaloomuuseumis Maarjamäe lossis avatud moenäitusest "Paula, sul on poisipea!", mille koostas Helle Avila, konsulteeris Anu Ojavee, kujundasid Krista Lepland ja Malle Jürgenson büroost Laika, Belka ja Strelka

  10. Tulevikulinna esimene maja / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    1999-01-01

    Santiago Calatrava juhtimisel valminud esimene ehitis Valencias asuvas nn. 'teaduste ja kunsti linnas'. 'Hemisfääriks' kutsutav hoone on betoonist, klaasist ja võrevormis terasest. Ka 'tarkusesilmaks' kutsutav ehitis asetseb ristkülikukujulise veekogu keskel. S. Calatravalt on tellitud 'linna' kolm peahoonet. Okeanograafilise pargi kujundab Félix Candela

  11. "Central Station" Londonis

    Index Scriptorium Estoniae

    2000-01-01

    Londoni galeriis Milch seitsme läti, leedu ja eesti kunstniku projekt "Central Station". Kuraatorid Lisa Panting, Sally Tallant. Eestist osalevad Hanno Soans (Catarina Campinoga koostöös valminud video), Kiwa, Kai Kaljo

  12. Download this PDF file

    African Journals Online (AJOL)

    cadewumi

    1,3, Wen-Chi Chen*4. 1Department of Urology, Chang Bing Show Chwan Memorial Hospital, 2Department of Life ..... with WLS was first recorded in the book written by Ken-Tang Wang entitled “Zheng Zhi Zhun Sheng” (standards of patterns and treatment) during the Ming Dynasty (late sixteenth century). Since that time, the ...

  13. Promoting better integration of health information systems: best practices and challenges

    NARCIS (Netherlands)

    Michelsen, K.; Brand, H.; Achterberg, P.; Wilkinson, J.

    2015-01-01

    Health Evidence Network Synthesis Report [Promoting better integration of health information systems: best practices and challenges K Michelsen, H Brand, P Achterberg, J Wilkinson - 2015 ... Authors Kai Michelsen Department of International Health, Maastricht University Maastricht,

  14. Kollaaž ja kontekst. Robert Rumase liiklusmärgid Tallinnas / Hanno Soans

    Index Scriptorium Estoniae

    Soans, Hanno, 1974-

    2004-01-01

    Sekkuv kunst. Poola kunstniku Robert Rumase (1966) rahvusvahelisest kunstiprojektist "Linnamanöövrid", Kai Kaljo videost "One way to see America", Krzysztof Wodicko "Kodutute projektsioonist" ja New York City Unioni väljaku ümberkorraldamisest

  15. 76 FR 13944 - Approval and Promulgation of Air Quality Implementation Plans; State of California; Regional Haze...

    Science.gov (United States)

    2011-03-15

    ... Wilderness; 14. Emigrant Wilderness; 15. Hoover Wilderness; 16. Yosemite National Park; 17. Ansel Adams... monitor) Ansel Adams WA, Kaiser WA, John 15.5 14.9 13.6 7.1 2200 Muir WA (KAIS monitor)......... Sequoia...

  16. Inglased kavatsevad Ida-Virumaale investeerida / Irina Tokareva

    Index Scriptorium Estoniae

    Tokareva, Irina

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 22. okt. 2004, lk. 4. Suurbritannia saatkonna esimehe aset. William Elliott ning tööstus- ja investeeringute jaoskonna assistent Kai Tomasberg viibisid Ida-Virumaal, kus nad veendusid regiooni soodsates investeerimistingimustes

  17. Põlvas tuli esitusele Andre Laine 29 tantsu / Mati Määrits

    Index Scriptorium Estoniae

    Määrits, Mati, 1958-

    2008-01-01

    Põlva Kultuuri- ja Huvikeskuses sai näha Põlvamaa Koolitantsu maakondlikku eelvooru. 52st tantsust 29 tantsu autor on Andre Laine. Kommenteerib ka Tartu Ülikooli Viljandi Kultuuriakadeemia lavakunstide osakonna tantsukunsti õppejõud Kai Valtna

  18. Genetics Home Reference: asphyxiating thoracic dystrophy

    Science.gov (United States)

    ... JL, Bacchelli C, Tuysuz B, Hill J, Rix S, Pearson CG, Kai M, Hartley J, Johnson C, Irving ... Accessibility FOIA Viewers & Players U.S. Department of Health & Human Services National Institutes of Health National Library of ...

  19. Production and characterization of wine from mango fruit ( Mangifera ...

    African Journals Online (AJOL)

    Production and characterization of wine from mango fruit ( Mangifera indica ) varieties in Kenya. ... Six mature and unripe mango fruits were harvested three times from a farm in Katheka Kai Division, Machakos County ... HOW TO USE AJOL.

  20. A weighted U-statistic for genetic association analyses of sequencing data.

    Science.gov (United States)

    Wei, Changshuai; Li, Ming; He, Zihuai; Vsevolozhskaya, Olga; Schaid, Daniel J; Lu, Qing

    2014-12-01

    With advancements in next-generation sequencing technology, a massive amount of sequencing data is generated, which offers a great opportunity to comprehensively investigate the role of rare variants in the genetic etiology of complex diseases. Nevertheless, the high-dimensional sequencing data poses a great challenge for statistical analysis. The association analyses based on traditional statistical methods suffer substantial power loss because of the low frequency of genetic variants and the extremely high dimensionality of the data. We developed a Weighted U Sequencing test, referred to as WU-SEQ, for the high-dimensional association analysis of sequencing data. Based on a nonparametric U-statistic, WU-SEQ makes no assumption of the underlying disease model and phenotype distribution, and can be applied to a variety of phenotypes. Through simulation studies and an empirical study, we showed that WU-SEQ outperformed a commonly used sequence kernel association test (SKAT) method when the underlying assumptions were violated (e.g., the phenotype followed a heavy-tailed distribution). Even when the assumptions were satisfied, WU-SEQ still attained comparable performance to SKAT. Finally, we applied WU-SEQ to sequencing data from the Dallas Heart Study (DHS), and detected an association between ANGPTL 4 and very low density lipoprotein cholesterol. © 2014 WILEY PERIODICALS, INC.

  1. Finnish Kalevala and Estonian Kalevipoeg / Jaan Puhvel

    Index Scriptorium Estoniae

    Puhvel, Jaan, 1932-

    2003-01-01

    Tõlgitud kogumikust: The world of the Kalevala : essays in celebration of the 150 year jubilee of the publication of the Finnish national epic / ed. Kai Laitinen. Los Angeles : UCLA Centre for the Study of Folklore & Mythology, 1987

  2. Developing institutional collaboration between Wageningen university and the Chinese academy of agricultural sciences

    NARCIS (Netherlands)

    Bonnema, A.B.; Lin, Z.; Qu, L.; Jacobsen, E.

    2006-01-01

    Scientific co-operation between the Chinese Academy of Agricultural Sciences (CAAS) and Wageningen University (WU) has been underway since 1990, especially in the field of plant sciences. In 2001, CAAS and WU initiated a formal joint PhD training programme to further structure their co-operation.

  3. Fundamental Investigations into the Infrared Properties of Carbon Nanotubes

    Science.gov (United States)

    2013-01-23

    Vallejo , Rongtao Lu, Judy Wu. Development of Textured Magnesium Oxide Templates on Amorphous Polymer SurfacesUsing Ion-Beam-Assisted Deposition, Applied...Applied Physics Letters 99, 023111 (2011) 18. A. Elliot, Vallejo , R.T. Lu, and J.Z. Wu, “Development of Textured Magnesium Oxides Templates on

  4. DMPD: Mechanism of age-associated up-regulation in macrophage PGE2 synthesis. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 15331118 Mechanism of age-associated up-regulation in macrophage PGE2 synthesis. Wu...e-associated up-regulation in macrophage PGE2 synthesis. PubmedID 15331118 Title Mechanism of age-associated... up-regulation in macrophage PGE2 synthesis. Authors Wu D, Meydani SN. Publicatio

  5. Darbo metu susenėjusių ir po suvirinimo termiškai apdorotų plieno 5 % Cr-0,5 % Mo virintinių jungčių struktūra ir savybės

    Directory of Open Access Journals (Sweden)

    Vigantas KUMŠLYTIS

    2012-06-01

    Full Text Available Straipsnyje nagrinėjamos suvirintos ir termiškai apdorotos chromo ir molibdeno (5 % Cr – 0,5 % Mo grupės plieno vamzdžių jungtys. Taip pat pateikiami ir palyginami ilgą laiką aukštoje temperatūroje eksploatuoto ir naujo chromo ir molibdeno plieno vamzdžio struktūra ir mechaninių savybių tyrimai. Eksploatuoto metalo tyrimams buvo panaudotas 530 °C temperatūroje 100 000 valandų dirbęs plieninis vamzdis. Tyrimais siekiama nustatyti 5 % Cr – 0,5% Mo grupės plienų suvirintųjų jungčių mechaninių savybių ir terminio apdorojimo parametrų tarpusavio priklausomybes. Atlikti suvirintų bandinių struktūros radiografiniai, mechaninių savybių, lūžių analizės ir mikrostruktūrų tyrimai. Nustatyta, kad chromo ir molibdeno plienų virintinių jungčių vidiniams įtempiams mažinti turi būti taikomas tik terminis apdorojimas. Kiti įtempių mažinimo metodai šiems plienams yra nepriimtini. Nustatyta, kad 5 % Cr – 0,5 % Mo plienų virintinių jungčių terminio apdorojimo temperatūros ir laiko parametro P reikšmė neturi viršyti 20,5. Viršijus šią reikšmę vyksta struktūros degradacijos procesas, karbidai pamažu transformuojasi į M23C6 karbidus, koaguliuoja ferito grūdelių ribose, sudaro karbidų kolonijas ar jungiasi į ilgus vientisus junginius. Smulkių, dispersiškų karbidų struktūroje nelieka. Taip pat mažėja jungties metalo takumo stipris ir smūginis tąsumas.DOI: http://dx.doi.org/10.5755/j01.ms.18.2.1911

  6. Characterization of new plasmids from methylotrophic bacteria.

    Science.gov (United States)

    Brenner, V; Holubová, I; Benada, O; Hubácek, J

    1991-07-01

    Several tens of methanol-utilizing bacterial strains isolated from soil were screened for the presence of plasmids. From the obligate methylotroph Methylomonas sp. strain R103a plasmid pIH36 (36 kb) was isolated and its restriction map was constructed. In pink-pigmented facultative methylotrophs (PPFM), belonging to the genus Methylobacterium four plasmids were detected: plasmids pIB200 (200 kb) and pIB14 (14 kb) in the strain R15d and plasmids pWU14 (14 kb) and pWU7 (7.8 kb) in the strain M17. Because of the small size and the presence of several unique REN sites (HindIII, EcoRI, NcoI), plasmid pWU7 was chosen for the construction of a vector for cloning in methylotrophs. Cointegrates pKWU7A and pKWU7B were formed between pWU7 and the E. coli plasmid pK19 Kmr, which were checked for conjugative transfer from E. coli into the methylotrophic host.

  7. Experimental validation of the Wigner distributions theory of phase-contrast imaging

    International Nuclear Information System (INIS)

    Donnelly, Edwin F.; Price, Ronald R.; Pickens, David R.

    2005-01-01

    Recently, a new theory of phase-contrast imaging has been proposed by Wu and Liu [Med. Phys. 31, 2378-2384 (2004)]. This theory, based upon Wigner distributions, provides a much stronger foundation for the evaluation of phase-contrast imaging systems than did the prior theories based upon Fresnel-Kirchhoff diffraction theory. In this paper, we compare results of measurements made in our laboratory of phase contrast for different geometries and tube voltages to the predictions of the Wu and Liu model. In our previous publications, we have used an empirical measurement (the edge enhancement index) to parametrize the degree of phase-contrast effects in an image. While the Wu and Liu model itself does not predict image contrast, it does measure the degree of phase contrast that the system can image for a given spatial frequency. We have found that our previously published experimental results relating phase-contrast effects to geometry and x-ray tube voltage are consistent with the predictions of the Wu and Liu model

  8. Kati Tolmoff: linn peabki oma sportlasi toetama / Maili Kangur

    Index Scriptorium Estoniae

    Kangur, Maili

    2009-01-01

    Tartlasest sulgpallur Kati Tolmoff sai Tartu Kultuurkapitali poolt olümpialootuse stipendiumi. Stipendiumi said ka Peeter Kümmel, Eveli Saue, Kristjan Kais, Rivo Vesik, Sirkka-Liisa Kivine, Tiidrek Nurme, Kaire Leibak, Künter Rothberg ja Maris Mägi

  9. Postkommunistlik kultuur ja kunst - kas müürid on lõhutud ? / Katrin Käärik ; foto: Katrin Käärik

    Index Scriptorium Estoniae

    Käärik, Katrin, 1950-

    1999-01-01

    Stockholmi Moodsa Kunsti Muuseumis avati 16. oktoobril 1999 rahvusvaheline näitus "Pärast müüri : kunst ja kultuur postkommunistlikus Euroopas", näitusest võtavad osa Jaan Toomik, Liina Siib, Kai Kaljo ja Inessa Josing

  10. Uus video, uus Euroopa / Kiwa

    Index Scriptorium Estoniae

    Kiwa, pseud., 1975-

    2006-01-01

    New Yorgi kunstikeskuses The Kitchen avatud endiste idablokimaade videokunstnike tööde näitusest. Eestlastest eksponeeritud Kiwa, Ene-Liis Semperi, Killu Sukmiti, Mari Laanemetsa, Tiia Johannsoni ja Kai Kaljo tööd. Kuraator Hamza Walker

  11. Rein and Zheng Elected to American Academy of Microbiology | Poster

    Science.gov (United States)

    By Nancy Parrish, Staff Writer Earlier this year, Alan Rein, Ph.D., and Zhi-Ming (Thomas) Zheng, M.D., Ph.D., were elected to fellowship in the American Academy of Microbiology, the honorific leadership group within the American Society for Microbiology (ASM). They were among 88 microbiologists who were elected to the academy “through a highly selective, peer-review process,

  12. Formation Energies of Native Point Defects in Strained-Layer Superlattices (Postprint)

    Science.gov (United States)

    2017-06-05

    potential; bulk materials; total energy calculations; entropy; strained- layer superlattice (SLS) 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF...AFRL-RX-WP-JA-2017-0217 FORMATION ENERGIES OF NATIVE POINT DEFECTS IN STRAINED- LAYER SUPERLATTICES (POSTPRINT) Zhi-Gang Yu...2016 Interim 11 September 2013 – 5 November 2016 4. TITLE AND SUBTITLE FORMATION ENERGIES OF NATIVE POINT DEFECTS IN STRAINED- LAYER SUPERLATTICES

  13. [Achievements and enlightenment of modern acupuncture therapy for stroke based on the neuroanatomy].

    Science.gov (United States)

    Chen, Li-Fang; Fang, Jian-Qiao; Chen, Lu-Ni; Wang, Chao

    2014-04-01

    Up to now, in the treatment of stroke patients by acupuncture therapy, three main representative achievements involving scalp acupuncture intervention, "Xing Nao Kai Qiao" (restoring consciousness and inducing resuscitation) acupuncture technique and nape acupuncture therapy have been got. Regarding their neurobiological mechanisms, the scalp acupuncture therapy is based on the functional localization of the cerebral cortex, "Xing Nao Kai Qiao" acupuncture therapy is closely related to nerve stem stimulation, and the nape acupuncture therapy is based on the nerve innervation of the regional neck-nape area in obtaining therapeutic effects. In fact, effects of these three acupuncture interventions are all closely associated with the modern neuroanatomy. In the treatment of post-stroke spastic paralysis, cognitive disorder and depression with acupuncture therapy, modern neuroanatomical knowledge should be one of the key theoretical basis and new therapeutic techniques should be explored and developed continuously.

  14. Klaasikunstnikud puhuvad ja valavad klaasi taas Haapsalus / Maris Sander

    Index Scriptorium Estoniae

    Sander, Maris

    2004-01-01

    Haapsalu 2. klaasipäevad "Maritima" (lad. keeles mereäärne) Evald Okase majamuuseumis. Osa võtavad kunstnikud Eestist, Koreast, Jaapanist ja Kanadast. Korraldaja Kai Koppel. Kommentaar Kati Kerstna. Valminud tööd pannakse näitusele

  15. [Eesti ajalugu III: Vene-Liivimaa sõjast Põhjasõjani] / Kalle Kroon

    Index Scriptorium Estoniae

    Kroon, Kalle, 1966-

    2014-01-01

    Arvustus. Enn Küng, Margus Laidre, Ivar Leimus, Aivar Põldvee, Anti Selart, Marten Sepepl, Kai Tafenau, Ülle Tarkiainen, Enn Tarvel. Eesti ajalugu III: Vene-Liivimaa sõjast Põhjasõjani. Tartu: Tartu Ülikooli Ajaloo ja Arheoloogia Instituut, 2013

  16. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Fang Dong1 Jiang Chenning1 Zhu Ting1 Yang Jinming1. Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering, Yancheng Teachers University, 50 Kai Fang Da Dao, Yancheng 224002, Jiangsu, P. R. China ...

  17. Ruumikujundused eelmisel aastal / Tuuli Org

    Index Scriptorium Estoniae

    Org, Tuuli

    2007-01-01

    Kokkuvõtted Kuressaare linna 2006. aasta ilusamatest ruumikujundustest: Ereki kontorihoone Pihtla tee 28 (Vello Liiv), kohvik Classic Lossi 9 (Kai Laanmets, Liina Saabas), Kuressaare gümnaasium Nooruse 1 (Vello Liiv), Vinoteek Lossi 4 (Ülle Kiirend, Anne Olop)

  18. Põhjalik koguteos Rootsi võidust / Kaarel Vanamölder

    Index Scriptorium Estoniae

    Vanamölder, Kaarel, 1981-

    2015-01-01

    Arvustus: Enn Küng, Margus Laidre, Ivar Leimus, Aivar Põldvee, Anti Selart, Marten Seppel, Kai Tafenau, Ülle Tarkiainen, Enn Tarvel. Eesti ajalugu III: Vene-Liivimaa sõjast Põhjasõjani. Tartu : Tartu Ülikooli Ajaloo ja arheoloogia instituut, 2013

  19. Research Article Special Issue

    African Journals Online (AJOL)

    pc

    2017-08-08

    Aug 8, 2017 ... Tupolev — KAI Kazan, Russian Federation. Published online: .... D and is the direct and an inverse DOT matrix of the dimension. N. N × ,. I. D. D. = ..... Embedded Programmable Logic Family/ Altera Inc. Cop. 1998. [Electronic.

  20. Hawking Temperature of Acoustic Black Hole Zhi Kun Xie

    Indian Academy of Sciences (India)

    Abstract. Using a new tortoise coordinate transformation, the Hawking radiation of the acoustic black hole was discussed by studying the Klein–. Gordon equation of scalar particles in the curve space-time. It was found that the Hawking temperature is connected with time and position on the event horizon. Key words.

  1. Vegetation Impact on Soil Strength: A State of the Knowledge Review

    Science.gov (United States)

    2017-06-20

    CRREL SR-17-2 3 soil layers. However, their more thorough look at the Wu (1976) and Wal- dron (1977) root–soil model for soil cohesion indicated a...trafficability and mobility simulations (Wu 1976; Waldron 1977; Wal- dron and Dakessian 1981 as cited in Pirnazarov and Sellgren 2015). Figure 6. Maximum

  2. Zavodõ jest, biodizelja - net / Viktor Filonenko

    Index Scriptorium Estoniae

    Filonenko, Viktor, 1949-

    2008-01-01

    Eestis on viimastel aastatel loodud mitu biodiislit tootvat ettevõtet, kuid Eestis puuduva nõudluse tõttu biodiislit siin ei müüda. Vt. samas: Taimsest toorainest valmistatakse kütust Paldiskis. Kommenteerivad Kai Realo, Indrek Kaju ja Sven Mark

  3. Sõrve suvelaager aitab hoida sidet esivanemate kodumaaga / Lembit Suur

    Index Scriptorium Estoniae

    Suur, Lembit

    2007-01-01

    1953. aastast tegutsenud Sõrve laagril on põlisosa Austraalia eestlaskonna noorte tegevuskavas, laagri juhtkond ja Sõrve Sõprade Komitee asutasid sellel aastal noorte juhtide ergutuseks Kai Rahneli nimelise juhtimisauhinna ja see määrati Ian Carterile ja Dorothy Queale´ile

  4. Rigturm de Viena

    Directory of Open Access Journals (Sweden)

    Boltenstern, Erich

    1959-05-01

    Full Text Available El nuevo edificio para el Servicio Municipal de Seguros de la ciudad de Viena se halla enclavado a orillas del Danubio, en la esquina de las dos calles principales de la capital de Austria, Schottenring y Kai.

  5. Kuidas Harjumaal vanasti elati? / Ell-Maaja Randküla

    Index Scriptorium Estoniae

    Randküla, Ell-Maaja, 1939-2016

    2006-01-01

    Harjumaa muuseumi (Keila, Linnuse 9) püsinäitus "Harju elu". Sisekujundus: Krista Lepland, Malle Jürgenson, Hedi Roots, OÜ Laika, Belka & Strelka. Ehitus: OÜ Alpimer Ehitus. Kai Kaljo maalitud põrandavaip. Ill.: plaan, 22 värv. vaadet

  6. Iz Berlina v Tampere za neskolko tshasov? / Helga Balode

    Index Scriptorium Estoniae

    Balode, Helga

    2002-01-01

    Rail Baltica raudtee, mis hakkab reisi- ja kaubaronge teenindama marsruudil Tallinn-Varssavi, läheb maksma miljardeid kroone. Kommenteerivad Soome transpordi- ja kommunikatsiooniministeeriumi nõunik Kai-Peter Mattson, Läti sideministeeriumi raudteeosakonnajuhataja Janis Veidmanis ja Eesti raudteeameti peadirektor Oleg Epner

  7. Euroopa abiraha igatseb taotlejaid / Ain Alvela

    Index Scriptorium Estoniae

    Alvela, Ain, 1967-

    2008-01-01

    Aastatel 2007-2013 saab Eesti Euroopa Liidult toetusi 78 miljardit krooni, millele toetudes on võimalik rasked ajad üle elada. Vt. samas: Tuhahoidlast asula jäätmepunktini; Suurima toetuse saab keskkond. Kommenteerivad Antti Tooming ja Kai Niels Willadsen

  8. Videokunsti parimad stiilinäited Kumus

    Index Scriptorium Estoniae

    2010-01-01

    Kumu Kunstimuuseumis avatakse 28. oktoobril 2010 rahvusvaheline videokunsti näitus "Kõik saab korda". Osalevad Marina Abramović (Serbia/USA), Eija-Liisa Ahtila (Soome), Kai Kaljo, Mike Marshall (Inglismaa), Ene-Liis Semper, Santeri Tuori (Soome), Guido van der Werve (Holland)

  9. Maret Maripuu : HIV-haigete raviks jätkub raha ka järgmisel aastal / Maret Maripuu ; interv. Ille Grün-Ots

    Index Scriptorium Estoniae

    Maripuu, Maret, 1974-

    2008-01-01

    Sotsiaalministri Maret Maripuu sõnul leiab HIV-i vältimise vajalikkus üha rohkem kõlapinda kogu ühiskonnas ja poolele teele seisma jääda ei tohi. Kommenteerib Lääne-Tallinna Keskhaigla nakkuskeskuse juhataja Kai Zilmer

  10. Minge vaadake väärtfilme / Andres Laasik, Kaarel Kressa

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2008-01-01

    !". PÖFFi filme - Leedu mängufilm "Kui ma olin partisan" ("Kai as buvau partizanas"), režissöör Vytautas V. Lansbergis ja Mehhiko - Hispaania mängufilm "Tsoon" ("La Zona"), režissöör Rodrigo Pla

  11. Breaking a chaos-based secure communication scheme designed by an improved modulation method

    Energy Technology Data Exchange (ETDEWEB)

    Li Shujun [Department of Electronic Engineering, City University of Hong Kong, Kowloon, Hong Kong (China)]. E-mail: hooklee@mail.com; Alvarez, Gonzalo [Instituto de Fisica Aplicada, Consejo Superior de Investigaciones Cientificas, Serrano 144-28006 Madrid (Spain); Chen Guanrong [Department of Electronic Engineering, City University of Hong Kong, Kowloon, Hong Kong (China)

    2005-07-01

    Recently Bu and Wang [Bu S, Wang B-H. Chaos, Solitons and Fractals 2004;19(4):919-24] proposed a simple modulation method aiming to improve the security of chaos-based secure communications against return-map-based attacks. Soon this modulation method was independently cryptanalyzed by Chee et al. [Chee CY, Xu D, Bishop SR. Chaos, Solitons and Fractals 2004;21(5):1129-34], Wu et al. [Wu X, Hu H, Zhang B. Chaos, Solitons and Fractals 2004;22(2):367-73], and Alvarez et al. [Alvarez G, Montoya F, Romera M, Pastor G. Chaos, Solitons and Fractals, in press, arXiv:nlin/0406065] via different attacks. As an enhancement to the Bu-Wang method, an improving scheme was suggested by Wu et al. by removing the relationship between the modulating function and the zero-points. The present paper points out that the improved scheme proposed by Wu et al. is still insecure against a new attack. Compared with the existing attacks, the proposed attack is more powerful and can also break the original Bu-Wang scheme. Furthermore, it is pointed out that the security of the modulation-based schemes proposed by Wu et al. is not so satisfactory from a pure cryptographical point of view. The synchronization performance of this class of modulation-based schemes is also discussed.

  12. Breaking a chaos-based secure communication scheme designed by an improved modulation method

    International Nuclear Information System (INIS)

    Li Shujun; Alvarez, Gonzalo; Chen Guanrong

    2005-01-01

    Recently Bu and Wang [Bu S, Wang B-H. Chaos, Solitons and Fractals 2004;19(4):919-24] proposed a simple modulation method aiming to improve the security of chaos-based secure communications against return-map-based attacks. Soon this modulation method was independently cryptanalyzed by Chee et al. [Chee CY, Xu D, Bishop SR. Chaos, Solitons and Fractals 2004;21(5):1129-34], Wu et al. [Wu X, Hu H, Zhang B. Chaos, Solitons and Fractals 2004;22(2):367-73], and Alvarez et al. [Alvarez G, Montoya F, Romera M, Pastor G. Chaos, Solitons and Fractals, in press, arXiv:nlin/0406065] via different attacks. As an enhancement to the Bu-Wang method, an improving scheme was suggested by Wu et al. by removing the relationship between the modulating function and the zero-points. The present paper points out that the improved scheme proposed by Wu et al. is still insecure against a new attack. Compared with the existing attacks, the proposed attack is more powerful and can also break the original Bu-Wang scheme. Furthermore, it is pointed out that the security of the modulation-based schemes proposed by Wu et al. is not so satisfactory from a pure cryptographical point of view. The synchronization performance of this class of modulation-based schemes is also discussed

  13. Biisofraxidin on Apoptosis of Human Gastric Cancer BGC-823 Cells

    African Journals Online (AJOL)

    Wu et al. Trop J Pharm Res, October 2015; 14(10): 1803. Tropical Journal of Pharmaceutical Research ... Jian-Tao Wu1,2*, She-Min Lv1, Chun-Hui Lu1, Jun Gong1 and Jian-Bo An3 ..... Zhu AK, Zhou H, Xia JZ, Jin HC, Wang K, Yan J, Zuo JB,.

  14. African Journal of Biotechnology - Vol 9, No 15 (2010)

    African Journals Online (AJOL)

    cDNA, genomic sequence cloning and overexpression of ribosomal protein S16 gene (RPS16) from the Giant Panda · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. W Hou, Y Hou, Y Hao, T Zhang, Z Peng, Y Wu, G Wu, 2185-2191 ...

  15. What Does it Take to Travel Philosophically Light? A Response to Nielsen

    Directory of Open Access Journals (Sweden)

    Idil Boran

    2008-10-01

    Full Text Available In his reply to criticism raised against his reading of Rawls’s constructivist method in light of Rorty’s pragmatism, Kai Nielsen defends his position on the basis that it provides the tools for an external defence of liberalism. An external defence seeks to justify a liberal conception of justice in a way that will be acceptable not only to those who have already accepted the core substantive principles of liberal theory, but to those who reject these core principles. This paper assesses Nielsen’s proposal and shows that Rortian pragmatism is a limited way of achieving an external defence of liberal political and legal institutions. I propose to develop instead the idea of Kantian constructivism to this end. This discussion also brings to light broader questions about the idea of practical philosophy, and thus pays tribute to the works of John Rawls, Richard Rorty, and Kai Nielsen. Dans sa réplique à la critique faite de son interprétation de la méthode constructiviste de Rawls à la lumière du pragmatisme de Rorty, Kai Nielsen défend sa position en indiquant qu’elle offre des outils pour faire une défense externe du libéralisme. Une défence externe cherche à justifier une conception libérale de la justice d’une façon qui sera acceptable non seulement par ceux qui ont déjà accepté les principes importants de fond de la théorie libérale, mais par ceux qui rejettent ces principes de fond. Cet article évalue la proposition de Nielsen et démontre que le pragmatisme de Rorty est une façon limitée d’en arriver à une défense externe des institutions politiques et juridiques libérales. Je propose de développer plutôt l’idée de constructivisme kantien à cette fin. Cette discussion fait aussi ressortir des questions de plus grande envergure au sujet de l’idée de philosophie pratique et rend ainsi hommage aux oeuvres de John Rawls, Richard Rorty et Kai Nielsen.

  16. Zhu Qing Wang

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Zhu Qing Wang. Articles written in Journal of Chemical Sciences. Volume 121 Issue 4 July 2009 pp 543-548. Highly sensitive optical chemosensor for the detection of Cu using a rhodamine B spirolatam · Gen Hua Wu Dong Xiang Wang Da Yu Wu Yuan Gao Zhu Qing Wang.

  17. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Anhua Wu. Articles written in Bulletin of Materials Science. Volume 27 Issue 4 August 2004 pp 333-336 Crystal Growth. Bridgman growth and defects of Nd : Sr3Ga2Ge4O14 laser crystals · Jiaxuan Ding Anhua Wu Jiayue Xu · More Details Abstract Fulltext PDF.

  18. Kirju sadam : High Tech Center, Tammasaarenkatu, Helsingi = On the waterfront : High Tech Centre

    Index Scriptorium Estoniae

    2004-01-01

    Projekt koosneb viiest hoonest, millest neli asetsevad mere ääres Tammasaare tänaval ja viies Kaapeli väljakul. Projekteerija: arhitektibüroo Wartiainen, Evata Finland. Autor Kai Wartiainen. Valmis 2002. I korruse plaan, 4 välis ja 2 sisevaadet

  19. Commutators of Integral Operators with Variable Kernels on Hardy ...

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 115; Issue 4. Commutators of Integral Operators with Variable Kernels on Hardy Spaces. Pu Zhang Kai Zhao. Volume 115 Issue 4 November 2005 pp 399-410 ... Keywords. Singular and fractional integrals; variable kernel; commutator; Hardy space.

  20. CRED Gridded Bathymetry of Nihoa Island and transit to Kauai (100-026) in the Northwestern Hawaiian Islands

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — File 100-026b is a 60-m ASCII grid of depth data collected near Nihoa multibeam bathymetry data from a SeaBeam 210 sonar aboard the R/V Kai'imikai-O-Kanaloa...

  1. CRED Gridded Bathymetry of St. Rogatien and Brooks Banks (100-018) in the Northwestern Hawaiian Islands

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — File 100-018b is a 60-m ASCII grid of depth data collected near St. Rogatien multibeam bathymetry data from a SeaBeam 210 sonar aboard the R/V Kai'imikai-O-Kanaloa...

  2. Siim Nestor soovitab : Circulation. Sugar Daddy and Girls. Sopot. Diskoteek. Club Unlimited / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2002-01-01

    Tallinnas: 25. mai disko-suurüritusest Circulation. 24. mail klubis Wimbledon disko Sugar Daddy and Girls. 25. mail Von Krahlis erinevate muusikastiilide üritus Sopot. 24. mail Decolte's esineb trance-muusika Dj-kuningas Kai Tracid. 25. mail Diskoteek Tartu klubis Terminal.

  3. Keda küll huvitaks teerullid ja asfalt? = Who's interested in steamrollers and asphalt? / Epp Lankots

    Index Scriptorium Estoniae

    Lankots, Epp, 1976-

    2006-01-01

    Eesti Maanteemuuseum Varbusel. Sise- ja ekspositsioonikujundus: Laika, Belka & Strelka OÜ. Autorid Krista Lepland, Malle Jürgenson, kaasautor Tea Tammelaan. Maalingud: Kai Kaljo. Projekteerija: OÜ Restauraatorprojekt. Arhitekt Aarne Kann. Projekt 2001-2004, valmis 2005. Ill.: asendiplaan, 6 värv. sisevaadet, välisvaade

  4. THE DOUBLE CALL FOR JOY, “REJOICE AND BE GLAD” (MATT. 5 ...

    African Journals Online (AJOL)

    How can this call be applied to our present situation? 2. FUNCTION AND ... macarisms of Matthew 5:3-12 fall under this grammatical form. Characteristic of a ..... 5:13-16). The two imperatives caivrete kai;ajg allia`sqe are more than simple du-.

  5. Creative style, personality, and artistic endeavor.

    Science.gov (United States)

    Gelade, Garry A

    2002-08-01

    Research has shown that creative style, as measured by the Kirton Adaption-Innovation Inventory (KAI; M. J. Kirton, 1976), is correlated with more than 30 different personality traits. In this article, the author demonstrates that many of these correlations can be understood within the framework of the Five-Factor Model of personality and shows that the predominant correlates of creative style are personality indicators in the domains of the factors Conscientiousness, Openness to Experience, and, to a lesser extent, Extraversion. These findings provide a basis for comparing the personality traits associated with creative style and occupational creativity. High scorers on the KAI (innovators) differ from both average and creative scientists but have personality characteristics similar to those of artists. This finding suggests that the artistic personality may be more common than is generally supposed and that common factors might underlie both artistic endeavor and creative style.

  6. PREFACE: The 15th International Conference on X-ray Absorption Fine Structure (XAFS15)

    Science.gov (United States)

    Wu, Z. Y.

    2013-04-01

    Committees and Staff Chair of the Conference Ziyu Wu International Advisory Committee Adam Hitchcock, Canada Adriano Filipponi, Italy Alain Manceau, France Alexander Soldatov, Russia Andrea Di Cicco, Italy Britt Hedman, USA Bruce Bunker, USA Calogero R. Natoli, Italy Christopher T. Chantler, Australia Frank M. F. De Groot, Netherlands Hiroyuki Oyanagi, Japan Ingolf Lindau, USA J. Mustre de Leon, México James E Penner-Hahn, USA Joaquin Garcia Ruiz, Spain John Evans, UK John J. Rehr, USA Kiyotaka Asakura, Japan Majed Chergui, Switzerland Mark Newton, UK Shiqiang Wei, P. R. China Tsun-Kong Sham, Canada Ziyu Wu, P. R. China International Program Committee Antonio Bianconi, Italy Augusto Marcelli, Italy Emad Flear Aziz, Germany Jinghua Guo, USA Joly Yves, France Masaharu Nomura, Japan Maurizio Benfatto, Italy Pieter Glatzel, France Shiqiang Wei, China Tiandou Hu, China Toshihiko Yokoyama, Japan Way-Faung Pong, Taiwan Xinyi Zhang, China Yi Xie, China Yuying Huang, China Zhonghua Wu, China Ziyu Wu, China Local Organizing Committee Bo He Fengchun Hu Haifeng Zhao Jing Zhang Meijuan Yu Qin Yu Shuo Zhang Wangsheng Chu Wei He Wei Xu Wensheng Yan Xiaomei Gong Xing Chen Yang Zou Yi Xia Zheng Jiang Zhi Xie Zhihu Sun Zhiyun Pan Additional Staff Chengxun Liu

  7. Synthesis of agarose–metal/semiconductor nanoparticles having ...

    Indian Academy of Sciences (India)

    Wintec

    Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur PO, Bangalore 560 064 b. Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific ..... Li P, Li J, Wu C, Wu Q and Li J 2005 Nanotechno- logy. 16 1912. 18. Gadi B and Jeffrey G 2005 Curr. Med. Chem. 12 2163. 19. Gadi B and ...

  8. Spectrum-effect relationships between high performance liquid ...

    African Journals Online (AJOL)

    promoting effect on contractility of intestinal smooth was carried out to ... addition, the equation of spectrum-effect relationships {Y = 3.818 - 1.126X1 + ..... Peng W, Liu YJ, Wu N, Sun T, He XY, Gao YX, Wu CJ. ... Zheng QF, Zhao YL, Wang JB, Liu TT, Zhang B, Gong ... Zhao HY, Han X. Research thoughts and application.

  9. Sustainable monitoring of roe deer in public hunting areas in the Spanish Pyrenes

    Energy Technology Data Exchange (ETDEWEB)

    Herrero, J.; Torres, R. T.; Prada, C.; Garcia-Serrano, A.; Gimenez-Anaya, A.; Fernandez, O.

    2013-07-01

    Aim of study: Monitoring trends in animal populations is essential for the development of appropriate wildlife management strategies. Area of study: The area is situated in the southern Pyrenees (Aragon), Spain. Material and methods: To measure the abundance, population trends, sex ratio, and mortality of roe deer populations, we analyzed data from i) driven hunts for wild boar (hunting seasons 1995/96-2009/10, n = 1,417, ii) itineraries, which were used to calculate the KAI and density using DS (2003-2010, n = 310 itineraries), iii) roe deer carcass recoveries (2006-2010, n = 100), and iv) data from the deer hunting quota fulfillment (2006-2010, n = 325 hunted animals. Main results: Based on DS, in 2010, the average density of roe deer populations was 2.3 km–2 (CV 17%). Based on the KAI and the battues, the estimated average annual rate of increase was 5.8% and 4.3%, respectively. Based on the KAI and the carcass recoveries, the estimates of the population sex ratio were 0.75 (n = 641) and 0.9 (n = 100) males per female, respectively. Carcass recoveries indicated that mortality was highest in late winter and early spring. The average body masses and sizes of males and females were within the ranges reported for other Iberian and European populations. Research highlights: Monitoring should be continued in the Aragon population of roe deer, although larger sample sizes are required to increase the accuracy of estimates and assessments of the impact of management actions. (Author)

  10. Two Viewpoints on the Challenges of ICT in Education: Knowledge-Building Theory vs. a Pragmatist Conception of Learning in Social Action

    Science.gov (United States)

    Kivinen, Osmo; Piiroinen, Tero; Saikkonen, Loretta

    2016-01-01

    The paper contrasts two different approaches to the educational challenges of the ubiquitous, rapidly developing information and communication technologies (ICT). The first is the constructivist "knowledge building" theory spearheaded by Carl Bereiter and Marlene Scardamalia and recently further developed by Kai Hakkarainen and Sami…

  11. Ela ja sära - setu pitsist ekvaatorireisini / Andres Keil

    Index Scriptorium Estoniae

    Keil, Andres, 1974-

    2004-01-01

    Eesti Kultuurkapitali "Ela ja sära" stipendiumi laureaadid kirjanik Eeva Park, kunstnik Kai Kaljo, sporditeadlane Joe Noormets, näitleja Kersti Kreismann, pitsikunstnik Ulve Kangro, režissöör Marko Raat, disainer Tarmo Luisk ja helilooja Urmas Sisask oma loomingulistest plaanidest

  12. 77 FR 48520 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

    Science.gov (United States)

    2012-08-14

    ... Berger SE; Westcon Holdings, Inc.; Bilfinger Berger SE. 20121084 G Sony Corporation; GaiKai Inc.; Sony..., 2012 Through July 31, 2012 07/02/2012 20121012 G Pinnacle West Capital Corporation; Edison International; Pinnacle West Capital Corporation. 20121022 G Vector Capital IV International. L.P.; Technicolor...

  13. Klaasis on pinget / Reet Varblane ; kommenteerinud Kati Kerstna, Kairi Orgusaar

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    2009-01-01

    Klaasi kui (kunsti)materjali kasutamisest, mitmete erialade sümbioosist. Laura Mattioli Rossi, Rosa Barovier Mentasti ja Adriano Berengo kureeritud näitusest "Glass Stress" ("Klaasipinge") tänavusel Veneetsia biennaalil. Eesti klaasikunstist, Kai Koppeli eestvedamisel toimunud Haapsalu klaasipäevadest "Kasuta päeva"

  14. Täna kell 17.30 avatakse Tallinna Kunstihoones briti, eesti ja soome fotonäitus "Fantastiline realism"

    Index Scriptorium Estoniae

    2004-01-01

    Kuraator Eve Kiiler. Osalejad loetletud. Avamisel esineb Naeruorgesster. 28. II seminaril räägib Asko Mäkela soome fotokunstist, David Bate briti fotost, Mike Marshall, Denny Robson, Outi Liusvaara, Marja Pirilä, Kai Kaljo ja Piret Räni presenteerivad oma töid

  15. Kodu Rotterdami kaubasadamas / Ada Org

    Index Scriptorium Estoniae

    Org, Ada

    2005-01-01

    Vabakutselise kunstniku Sandy omapärasest kolmekorruselisest tellistest elamust aadressil kai number 2600. Enamus mööblist on korduvkasutuses, asjadele on leitud uus funktsioon, remonditööd on teinud Sandy ise. Kolmandal korrusel asuva vannitoa sisustus on uus. 13 värv. ill

  16. Department of Defense Atlas/Data Abstract for the United States and Selected Areas. Fiscal Year 1992

    Science.gov (United States)

    1993-01-01

    ZIMMERMIANN BASIL CORP JV 34,679 Operation/Ammunition Facilities 34,679 3. MORRISON KNUDSEN CORP 30,923 Facilities Operations Support Services 30,923 4...qFEMBACfl A A ABA NUERNBERG HEIDELBERG KAI-3ERSLAUTERN ASTUTTG ART Prepared Byt Washington Headquarters Servicee Directorate for Information Operations

  17. Internet seinakontaktist on tulevikumuusika / Kai Simson

    Index Scriptorium Estoniae

    Simson, Kai

    2004-01-01

    Näitusel Enerex 2004 tutvustas Schneider Electric Eesti AS esmakordselt Power Line Communicationi (PLC) ühendust, millega saab Internetti edastada ja jagada elektrivõrgu kaudu. Kommenteerivad Fortum Elekter AS-i Läänemaa regiooni võrgujuht Kaupo Kuurberg, Elion Ettevõtted AS-i meediasuhete juht Ain Parmas ja Eesti Energia Televõrgu AS-i juhataja Urmas Aiaste

  18. Märkmeid tantsuaastast 2003 / Kai Valtna

    Index Scriptorium Estoniae

    Valtna, Kai

    2004-01-01

    Ülevaade 2003. aasta tantsulavastustest Eesti lavadel. Pikemalt peatutakse lavastustel "Armastuse tango ehk Aegade lõpus" (lav. M. Murdmaa), "Outbound" (lav. M. Moles), "Mart on stage" (lav. M. Kangro), "Luikede järv" (lav. P. Jalakas ja S. Pepeljajev)

  19. Maksureformist saab valitsuse kirstunael / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2005-01-01

    2006. aasta eelarve kokkupanemine ja eelarvestrateegia kinnitamine aastateks 2006-2009 võib aprillis-mais koalitsioonipartnerid taas konfliktini viia, kuna kahe järgneva aasta vältel ei ole võimalik samaaegselt langetada tulumaksu 20 protsendini ja täita koalitsioonileppe lubadusi. Lisad: Reformi juhatuses sisepinged; Maksureform

  20. Computer Graphics Research Laboratory Quarterly Progress Report Number 49, July-September 1993

    Science.gov (United States)

    1993-11-22

    20 Texture Sampling and Strength Guided Motion: Jeffry S. Nimeroff 23 21 Radiosity : Min-Zhi Shao 24 22 Blended Shape Primitives: Douglas DeCarlo 25 23...placement. "* Extensions of radiosity rendering. "* A discussion of blended shape primitives and the applications in computer vision and computer...user. Radiosity : An improved version of the radiosity renderer is included. This version uses a fast over- relaxation progressive refinement algorithm

  1. BIOTECHNOLOGICAL APPLICATIONS AND POTENTIAL USES OF THE MUSHROOM TRAMESTES VERSICOLOR

    OpenAIRE

    CÓRDOBA M., Ketty A.; RÍOS H., Alicia

    2012-01-01

    The use of products obtained from fungi (particularly mushrooms) has increased lately due to their broad applicability in different scientific and industrial fields. The genus Trametes comprises a group of white rot producing ligninolytic fungi, with medicinal properties, biotechnological importance and environmental applications. One of the most potentially useful species is T. versicolor, formerly known as Coriolus versicolor or Polyporus versicolor. Also known as Yun Zhi in China, is a fun...

  2. Mis jääb kunstist lõpuks sõelale? / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2011-01-01

    15. Tallinna graafikatriennaalist "Armastuse, mitte raha pärast" Kumu Kunstimuuseumis. Triennaali kuraatorid: Simon Rees, Eve Kask, Eha Komissarov, kujundajad: Neeme Külm, Ralf Lõoke. Óskar Muñoze (Colombia), Ellie Daviesi (Suurbritannia), Andrew Raftery (USA), Kai Kuusingu ja Anu Kalmu töödest

  3. Klaas ja mõis / Maie-Ann Raun

    Index Scriptorium Estoniae

    Raun, Maie-Ann, 1938-

    2007-01-01

    Klaasikunstinäitus "Ringkäik" Albu mõisas, kuraatorid Virve Kiil, Kati Kerstna, Kairi Orgusaar. Eksponeeritakse Tiina Sarapu, Mare Saare, Eeva Käsperi, Kai Kiudsoo-Värvi, Pilvi Ojamaa, Merle Bukoveci, Kalli Seina, Viivi-Ann Keerdo, Liisi Junolaineni, Kristiina Uslari, Ivo Lille töid

  4. Tartu Ülikool raamatukogus / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2005-01-01

    Kuni 13 II näitus "R.A.I.S.K." (Radikaalne Agiteeriv Intrigeeriv Sotsiaalne Kunst). Krutskilist ökokunsti teevad Infotankistid, Puhas Rõõm, Piret Räni, Maris Suits, Katrin Tees, Anu Vahtra, Mart Viljus, Ivika Kivi & Sulo Kallas, Taavi Suits, Kai Herkel ja Henry van Noordenburg

  5. Uma leitura intertextual da poesia de Alberto Caeiro à luz da sabedoria zen-budista

    Directory of Open Access Journals (Sweden)

    Márcia Munir Miguel Feitosa

    2011-10-01

    Full Text Available Análise da poesia de Alberto Caeiro, heterônimo de Fernando Pessoa, à luz da filosofia zen-budista, tanto no que concerne ao culto da natureza, como no que diz respeito à questão do eu, inerente ao poeta português e à filosofia Zen. O estudo ainda inclui o levantamento das possíveis afinidades formais e estilísticas entre a poesia japonesa, representada pelos hai-kais, e a poesia sensacionalista de Caeiro.Análisis de la poesia de Alberto Caeiro, heterónimo de Fernando Pessoa a la luz de la filosofía zen-budista, tanto que concierne al culto de la naturaleza, como que dice respecto a la cuestión del yo, inherente al poeta portugués y a la filosofía zen. El estúdio aún incluye las posibles afinidades formales y estilísticas entre la poesia japonesa, representada por los hai-kais, y la poesia sensacionista de Caeiro.

  6. Hard X-ray photoemission spectroscopy

    International Nuclear Information System (INIS)

    Kobayashi, Keisuke

    2009-01-01

    Except in the very early stage of the development of X-ray photoemission spectroscopy (XPS) by Kai Siegbahn and his coworkers, the excitation sources for XPS studies have predominantly been the Al Kα and Mg Kα emission lines. The advent of synchrotron radiation sources opened up the possibility of tuning the excitation photon energy with much higher throughputs for photoemission spectroscopy, however the excitation energy range was limited to the vacuum ultra violet and soft X-ray regions. Over the past 5-6 years, bulk-sensitive hard X-ray photoemission spectroscopy using high-brilliance high-flux X-rays from third generation synchrotron radiation facilities has been developed. This article reviews the history of HXPES covering the period from Kai Siegbahn and his coworkers' pioneering works to the present, and describes the fundamental aspects, instrumentation, applications to solid state physics, applied physics, materials science, and industrial applications of HXPES. Finally, several challenging new developments which have been conducted at SPring-8 by collaborations among several groups are introduced.

  7. Download this PDF file

    African Journals Online (AJOL)

    pc

    2017-11-10

    Nov 10, 2017 ... ts of alkyl chain length on particles morphology were primarily studied ..... [3] Li Z, Yu L, Zheng L, Li N, Han S, Li G. Characterization studies on the ionic ... [4] Chiang YD, Lian HY, Leo SY, Wang SG, Yamauchi Y, Wu KC. ... [20] Yu YJ, Xing JL, Pang JL, Jiang SH, Lam KF, Yang TQ, Xue QS, Zhang K, Wu P.

  8. Effects of Estradiol on Post-Traumatic Stress Disorder Symptoms

    Science.gov (United States)

    2010-03-01

    Directed By: T. John Wu, Ph.D. Associate Professor, Department of Obstetrics and Gynecology Post-traumatic stress disorder (PTSD) is a complex...Preventing post-traumatic stress disorder after mass exposure to violence . Biosecur Bioterror 2005;3:154-63; discussion 64-5. 16. Baker DG...John Wu* Affiliations: *Program in Neuroscience and § Program in Molecular and Cellular Biology, Department of Obstetrics and Gynecology Uniformed

  9. The Frontier National Society Viewed by WU Luzhen:Case of East Simeng Survey in Inner Mongolia%吴禄贞视野中的边疆民族社会①--以内蒙古东四盟调查为例

    Institute of Scientific and Technical Information of China (English)

    王鹏辉

    2015-01-01

    Inner Mongolia Dongsimeng region formed Mongolian and Han mixed pattern of survival in Qing Dynasty, and formed an in-terdependent community of destiny. WU lu-zhen survey showing the internal crisis of Inner Mongolia Dongsimeng borderland ethnic society, involving many aspects,such as politics, livelihoods and economies, religion and customs, which showed its domestic policy and internation-al aggression interaction mechanism of social contradictions and resulted in the frontier ethnic society in Modern China.%有清一代,内蒙古东四盟地域已经形成蒙汉杂居的生存格局,并且结成相互依存的命运共同体。吴禄贞的调查呈现出内蒙古东四盟边疆民族社会的内在危机,涉及政治、生计与经济、宗教与风俗诸多方面,显现其国内新政与国际侵略互动的社会矛盾机制。内蒙古东四盟身处清末国内国际两种交冲的力量与历史传统的碰撞,逐渐生成中国近代的边疆民族社会。

  10. Tundmatu eesti disain / Ivar Sakk

    Index Scriptorium Estoniae

    Sakk, Ivar, 1962-

    2006-01-01

    Eesti disainist, selle teadvustamisest, disainiajaloo puudumisest. Eesti keraamika ajaloost on kirjutanud Leo Rohlin, klaasikunsti ajaloost Maie-Ann Raun, sisearhitektuuri ajaloost Krista Kodres. Kai Lobjakas on kirjutanud ülevaate "Märkmeid eesti disainist". Saksa disaineri Serge Rompza ja ameerika disainiteoreetiku Victor Margolini arvamusest näituse "Ajast ees" kohta

  11. Admiral Pitka kantakse maha

    Index Scriptorium Estoniae

    2013-01-01

    Kaitsevägi on otsustanud arvata teenistusest välja Eesti mereväe lipulaeva Admiral Pitka, mis tehakse varustusest tühjaks ja tagastatakse Taani kuningriigile. Miinitõrjeoperatsiooni või õppuse juhtimiseks mõeldud 74 meetri pikkune fregatt on seisnud rahapuudusel kai ääres 2008. aastast

  12. NREL Research Pushes Perovskites Closer to Market | News | NREL

    Science.gov (United States)

    even get close-to the above-20% efficiencies dominated by silicon solar panels. NREL researcher Kai Zhu ; Perovskites have a couple of major benefits over silicon solar panels. The silicon technology requires a high as excellent semiconductors. This means perovskite panels are more flexible than rigid silicon panels

  13. Modelling the autocovariance of the power spectrum of a solar-type oscillator

    DEFF Research Database (Denmark)

    Campante , T.L.; Karoff, Christoffer

    2010-01-01

    tool in the analysis of the more than 1000 solar-type stars expected to be observed as part of the Kepler Asteroseismic Investigation (KAI). We apply the aforementioned procedure to simulations of the Sun. Assuming different apparent magnitudes, we address the issues of how accurately and how precisely...

  14. Patterns of Cenozoic sediment flux from western Scandinavia

    DEFF Research Database (Denmark)

    Gołędowski, Bartosz; Nielsen, S.B.; Clausen, O.R.

    2012-01-01

    deposits in the North Sea, the post-mid-Miocene Molo and Kai Formations of the Norwegian Shelf, the southern North Sea delta system and large volumes of the Late Pliocene-Holocene Naust Formation. The sediment flux from Scandinavia during the Cenozoic is in general agreement with the detrital flux...

  15. The future existence of the believers according to 2 Thessalonians

    African Journals Online (AJOL)

    Test

    2010-08-14

    tan e[lqh/ ejndoxasqh nai ejn toi aJgivoi aujtou kai; qaumasqh nai ejn ... God and those who do not obey the gospel of our Lord Jesus'. (2 Th 1:8). ... John 3:2 and Revelation 22:4.25 It is a motif widely found in. Hebrew ...

  16. Kõik saab korda / Tamara Luuk

    Index Scriptorium Estoniae

    Luuk, Tamara, 1952-

    2010-01-01

    Rahvusvaheline videokunsti näitus "Kõik saab korda" Kumu Kunstimuuseumis 2. jaanuarini 2011. Kuraator Maria-Kristiina Soomre, kujundaja Berit Teeäär. Osalevad Marina Abramović (Serbia/USA), Eija-Liisa Ahtila (Soome), Kai Kaljo, Mike Marshall (Inglismaa), Ene-Liis Semper, Santeri Tuori (Soome), Guido van der Werve (Holland)

  17. Ida-Euroopa postkommunistliku kunsti näitus tulemas

    Index Scriptorium Estoniae

    1999-01-01

    Stockholmi uues Moderna Museeti hoones avab kuraatorite kollektiiv 16. okt. 1999 näituse "After the Wall", mis analüüsib Berliini müüri langemise järgset kunstiolukorda ja kultuurimuutusi Ida-Euroopas. Näitusele on valitud eestlastest Inessa Josing, Kai Kaljo, Liina Siib, Jaan Toomik

  18. ACUTE-TO-CHRONIC ESTIMATION (ACE V 2.0) WITH TIME-CONCENTRATION-EFFECT MODELS: USER MANUAL AND SOFTWARE

    Science.gov (United States)

    Ellersieck, Mark R., Amha Asfaw, Foster L. Mayer, Gary F. Krause, Kai Sun and Gunhee Lee. 2003. Acute-to-Chronic Estimation (ACE v2.0) with Time-Concentration-Effect Models: User Manual and Software. EPA/600/R-03/107. U.S. Environmental Protection Agency, National Health and Envi...

  19. Radiotherapy-related typing in 842 patients in canton with nasopharyngeal carcinoma

    International Nuclear Information System (INIS)

    Li Zhiqiang; Xia Yunfei; Liu Qing; Yi, Wei; Liu Xiufang; Han Fei; Luo Wei; Lu Taixiang

    2006-01-01

    Purpose: The aim of this study was to propose the clinical radiotherapy-related typing and to summarize proportional distribution of radiotherapy-related types of nasopharyngeal carcinoma (NPC). Methods and Materials: A total of 842 cases of NPC were randomly selected. According to 5-year follow-up results after radiotherapy, NPC was subdivided into four types: Type I (no primary and regional recurrence and no distant metastasis), Type II (primary or regional recurrence and no distant metastasis), Type III (no primary and regional recurrence, and distant metastasis), and Type IV (primary or regional recurrence, and distant metastasis). Proportion of the four types and relationship between this typing and Zhi-guang Xie typing were analyzed. Results: Distribution of radiotherapy-related types of NPC were 50.6%, 23.2%, 20.7%, and 5.6% for Types I, II, III, and IV, respectively. For Types D and AD of Zhi-guang Xie typing system and Stage III and IV of the 1992 Fuzhou staging system, the proportion of Type III was greater than that of Type II; and for Type A and Stage I and II, there was a larger proportion of Type II than that of Type III. Conclusion: Radiotherapy-related typing, as a new clinical subclassification, could be supplementary for previous clinical typing and staging

  20. SYNTHESES, STRUCTURES AND PROPERTIES Jian Wu1*, Fu

    African Journals Online (AJOL)

    Preferred Customer

    Printed in Ethiopia. © 2014 Chemical Society of Ethiopia ... 1Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi University ... The O–H···O and C–H···Cl hydrogen-bonding interactions play a significant role in.

  1. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    CHEN AI-HUA1 MENG SU-CI2 ZHOU KAI1 WANG CONG-CONG1 ZHAO WEI2 WANG AI-JIAN2 QIAN JUN2. School of Chemistry & Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, People's Republic of China; School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang ...

  2. Final Report: Multi-Scale Analysis of Deformation and Failure in Polycrystalline Titanium Alloys Under High Strain-Rates

    Science.gov (United States)

    2015-12-28

    element simulations of polycrystalline Tita - nium alloys. Jour. Mech. Phys. Solids, 59(10):2157–2176, 2011. 5. S. Ghosh and M. Anahid. Homogenized...2013) 111 – 124. [72] P. Shade, Private communication. [73] H. Ogi, S. Kai, H. Ledbetter, R. Tarumi, M. Hirao, K. Takashima, Tita - niums high-temperature

  3. Mäss põhjusega : kortermaja Silodamil Amsterdamis / Klaske Havik

    Index Scriptorium Estoniae

    Havik, Klaske, 1975-

    2002-01-01

    Büroo MVRDV suurim elamuprojekt. Arhitektid Winy Maas, Jacob van Rijs, Nathalie de Vries, kaasa töötasid Frans de Witte, Willem Timmer, Eline Strijkers, Bernd Felsinger, Duzan Koepel. Viis võistlustöö kaasautorit. Hoone paikneb kai tipus, on ehitatud vette postide peale. Ill.: 7 plaani, 11 vaadet

  4. No mixed feelings : The post-Lisbon Common Commercial Policy in Daiichi Sankyo and Commission v. Council (Conditional Access Convention)

    NARCIS (Netherlands)

    Larik, J.E.

    2015-01-01

    Double case note on the scope of the EU's Common Commercial Policy and the future of "mixed agreements" based on the two ECJ Grand Chamber Judgements Case C-414/11, Daiichi Sankyo Co. Ltd and Sanofi-Aventis Deutschland GmbH v. DEMO Anonimos Viomichaniki kai Emporiki Etairia Farmakon, Judgment of the

  5. Igavese armastuse sõdalane : mitte just klassika, aga ajaloo verstapost küll / Ilmar Raag

    Index Scriptorium Estoniae

    Raag, Ilmar, 1968-

    2006-01-01

    Soome ja Hiina mütoloogiat ühendavast fantaasiafilmist "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina, Hollandi, Eesti ühistöö) : stsenarist Iiro Küttner, režissöör Antti-Jussi Annila, võitluskunstide koreograaf Yu Yan Kai, osades - Tommi Eronen, Zhang Jingchu, Markku Peltola, Elle Kull

  6. Fassaadikunstist ja teesklusest / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2006-01-01

    Soome ja Hiina mütoloogiat ühendav fantaasiafilm "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina, Hollandi ja Eesti ühistöö) : stsenarist Iiro Küttner : režissöör Antti-Jussi Annila : võitluskunstide koreograaf Yu Yan Kai : osades Tommi Eronen, Zhang Jingchu, Markku Peltola

  7. Novõi utshebnõi god budjet Godom dizaina / Ksenia Repson

    Index Scriptorium Estoniae

    Repson, Ksenia

    2006-01-01

    Eesti Kunstiakadeemia disainihariduse 40. aastapäeva tähistava Disainiaasta üritusi: rahvusvaheline disainikonverents Connecting, näitus "40 aastat disaini" Tarbekunsti- ja Disainimuuseumis, disainikonkurss, rändnäitused, seminarid, Tallinna disainikaart (koostab Kai Lobjakas, joonistavad Indrek Sirkel ja Mikk Heinsoo). Projekti "Disainiaasta" juht on Ruth Helene Melioranski

  8. Resurrecting past futures / Thomas Cubbin

    Index Scriptorium Estoniae

    Cubbin, Thomas, 1987-

    2011-01-01

    Näitused "Modernisation. Baltic Art, Design and Architecrure in the 1960s-1970s" (kuraatorid Lolita Jablonskienė, Kai Lobjakas, Iliana Veinberga) ja "Our Metamorphic Futures: Design, technical aesthetics and experimental architecture in the Soviet Union 1960-1980" (kuraatorid Andres Kurg, Mari Laanemets) Vilniuse Rahvusgaleriis 9.12.2011-12.02.2012

  9. Uus Tartu Loodusmaja = The new Tartu Nature Building / Tiit Sild

    Index Scriptorium Estoniae

    Sild, Tiit, 1977-

    2010-01-01

    Tartu Loodusmaja avalikust arhitektuurivõistlusest, kvalifitseerimistingimustest, energiatõhususest ja žürii tööst. 1. preemia sai töö "Känd", autorid Diana Taalfeld, Kai Süda, Margit Valma, Martin Kinks (Urmas Lõokese AB / Karisma Arhitektid). Nimetatud 2. ja 3. koha saanud tööd, autorid

  10. Unearthing the Past

    DEFF Research Database (Denmark)

    Bagger-Petersen, Mai Corlin

    2013-01-01

    Wu Wenguang, considered the father of independent Chinese documentary film, has since 2005 slowly but surely been handing over the camera to people on the margins and to younger generations of Chinese documentary filmmaking. In 2010 Wu and Caochangdi Workstation initiated the Folk Memory Document...... Documentary Project, where young filmmakers go to the countryside to gather and document memories of the Great Famine (1959-1961) from elderly villagers....

  11. The 2nd International Conference on Water Resource and Environment (WRE 2016

    Directory of Open Access Journals (Sweden)

    Zhouli Liu

    2016-11-01

    Full Text Available Table of contents 01 The eco-toxicological effects of cadmium stress on five ornamental plants Zhouli Liu, Wei Chen, Xingyuan He, Shuai Yu, Weihang Ding 02 Study on the formation and release mechanisms of hydrogen sulfide in Longtan coal mine Jianjun Liu, Yuliang Wu, Kaixiang Fan 03 Coral bleaching in the North Reef of China’s Xisha Islands in 2014 Yuanchao Li, Xinqing Zheng, Shiquan Chen, Haiqun Xie 04 Soil chemical characteristics in a Cunninghamia lanceolata stand suffering from ice-snow damage Jie Li, Zhuomin Wang, Li Xue 05 Diversity of understory vegetation was under a Cunninghamia lanceolata stand suffering from ice-snow damage Zhiyang Lie, Weilong Huang, Tongtong Zhou, Li Xue 06 The effect of water, nitrogen and harvesting time on yield and biomass allocation of Helianthus tuberosus L. Kai Gao, Tiexia Zhu 07 The vertical variation of microbial communities in the sediment of sea cucumber pond Weiteng Mao, Pei Yu, Xinfang Lv, Yunchun Li 08 Indicating significances of alpine plant functional groups to environmental change Peixi Su, Rui Shi 09 Research on the daily CH4 fluxes of soil in summer mangrove community at Yingluogang of Guangxi, China Yong Jiang, Xingbin Chen, Shichu liang 10 Beach protection structures in middle and lower reaches of Yangtze River Junfeng Xu 11 Social responsibility management of large dam project with owner as core: an empirical case in China Jiwei Zhu, Zhao Zhai, Linan Zhou, Yun Le, Li Cao 12 The ecological function value assessment analysis of urban waterfront Jiwei Zhu, Ping Lu, Zhiqian Huang, Bei Zhou 13 Mechanism of diurnal osmotic potential changes and adjustment of three Caragana species in different habitats of the Inner Mongolia Plateau Zhirong Zheng, Shihai Lv, Chaoyang Feng 14 Biodiversity of phytoplankton and environmental influences analysis of Longfeng Wetland, China Nan Song, Yan Liu, Xinxin Lu, Yawen Fan 15 The effect of human activities on culturable soil microbes from Yaoquan Mountain in

  12. Microbially-Mediated Precipitation of Calcium Carbonate Nanoparticles.

    Science.gov (United States)

    Kang, Ser Ku; Roh, Yul

    2016-02-01

    The objective of this study was to investigate the biomineralization of carbonate minerals using microorganisms (Wu Do-1) enriched from rhodoliths. A 16S rRNA sequence analysis showed that Wu Do-1 mainly contained Proteus mirabilis. The pH decreased from 6.5 to 5.3 over the first 4 days of incubation due to microbial oxidation of organic acids, after which it increased to 7.8 over the remaining incubation period. XRD analysis showed that the precipitates were Mg-rich cal- cite (MgxCa(1-x)CO3), whereas no precipitates were formed without the addition of Wu Do-1 in D-1 medium. SEM-EDS analyses showed that the Mg-rich calcite had a rhombohedron shape and consisted of Ca, Si and Mg with an extracelluar polymeric substance (EPS). In addition, TEM-EDS analyses revealed they were hexagon in shape, 500-700 nm in size, and composed of Ca, Mg, C, and O. These results indicated that Wu Do-1 induced precipitation of Mg-rich calcite on the cell walls and EPS via the accumulation of Ca and/or Mg ions. Therefore, microbial precipitation of carbonate nanoparticles may play an important role in metal and carbon biogeochemistry, as well as in carbon sequestration in natural environments.

  13. Does Vibration Warm-up Enhance Kinetic and Temporal Sprint Parameters?

    Science.gov (United States)

    Cochrane, D J; Cronin, M J; Fink, P W

    2015-08-01

    The aim of this study was to investigate the efficacy of vibration warm-up to enhance sprint performance. 12 males involved in representative team sports performed 4 warm-up conditions in a randomised order performed at least 24 h apart; VbX warm-up (VbX-WU); Neural activation warm-up (Neu-WU); Dynamic warm-up (Dyn-WU) and Control (No VbX). Participants completed 5 m sprint at 30 s, 2:30 min and 5 min post warm-up where sprint time, kinetics, and temporal components were recorded. There was no significant (p>0.05) main effect or interaction effect between the split sprint times of 1 m, 2.5 m, and 5 m. There was a condition effect where vertical mean force was significantly higher (p0.05) main and interaction effects in sprint kinetic and temporal parameters existed. Overall, all 4 warm-up conditions produced comparable results for sprint performance, and there was no detrimental effect on short-duration sprint performance using VbX-WU. Therefore, VbX could be useful for adding variety to the training warm-up or be included into the main warm-up routine as a supplementary modality. © Georg Thieme Verlag KG Stuttgart · New York.

  14. A Multiscale Modeling System: Developments, Applications, and Critical Issues

    Science.gov (United States)

    Tao, Wei-Kuo; Lau, William; Simpson, Joanne; Chern, Jiun-Dar; Atlas, Robert; Khairoutdinov, David Randall Marat; Li, Jui-Lin; Waliser, Duane E.; Jiang, Jonathan; Hou, Arthur; hide

    2009-01-01

    The foremost challenge in parameterizing convective clouds and cloud systems in large-scale models are the many coupled dynamical and physical processes that interact over a wide range of scales, from microphysical scales to the synoptic and planetary scales. This makes the comprehension and representation of convective clouds and cloud systems one of the most complex scientific problems in Earth science. During the past decade, the Global Energy and Water Cycle Experiment (GEWEX) Cloud System Study (GCSS) has pioneered the use of single-column models (SCMs) and cloud-resolving models (CRMs) for the evaluation of the cloud and radiation parameterizations in general circulation models (GCMs; e.g., GEWEX Cloud System Science Team 1993). These activities have uncovered many systematic biases in the radiation, cloud and convection parameterizations of GCMs and have led to the development of new schemes (e.g., Zhang 2002; Pincus et al, 2003; Zhang and Wu 2003; Wu et al. 2003; Liang and Wu 2005; Wu and Liang 2005, and others). Comparisons between SCMs and CRMs using the same large-scale forcing derived from field campaigns have demonstrated that CRMs are superior to SCMs in the prediction of temperature and moisture tendencies (e.g., Das et al. 1999; Randall et al 2003b; Xie et al. 2005).

  15. Implementation of envelope detection based Wake-Up Receiver for IEEE 802.15.4 WPAN from off-the-shelf components

    Science.gov (United States)

    Arndt, Josua; Krystofiak, Lukas; Bonehi, Vahid; Wunderlich, Ralf; Heinen, Stefan

    2017-09-01

    Power consumption in wireless networks is crucial. In most scenarios the transmission time is short compared to the idle listening time for data transmission, the most power is consumed by the receiver. In low latency systems there is a need for low power wake-up receivers (WuRx) that reduce the power consumption when the node is idle, but keep it responsive. This work presents a WuRx designed out of commercial components to investigate the needs of a WuRx when it is embedded in a Wireless Personal Area Network (WPAN) system in a real environment setup including WLAN and LTE communication and considering interferer rejection. The calculation necessary for the attenuation of those interferers is explained in detail. Furthermore, a system design is presented that fulfills the requirements for this environment and is build from off-the-shelf components.

  16. Stochastic spin-one massive field

    International Nuclear Information System (INIS)

    Lim, S.C.

    1984-01-01

    Stochastic quantization schemes of Nelson and Parisi and Wu are applied to a spin-one massive field. Unlike the scalar case Nelson's stochastic spin-one massive field cannot be identified with the corresponding euclidean field even if the fourth component of the euclidean coordinate is taken as equal to the real physical time. In the Parisi-Wu quantization scheme the stochastic Proca vector field has a similar property as the scalar field; which has an asymptotically stationary part and a transient part. The large equal-time limit of the expectation values of the stochastic Proca field are equal to the expectation values of the corresponding euclidean field. In the Stueckelberg formalism the Parisi-Wu scheme gives rise to a stochastic vector field which differs from the massless gauge field in that the gauge cannot be fixed by the choice of boundary condition. (orig.)

  17. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    Li-Long Liu, Kai Xu, Lu-Mei Kang, Shu-Ping Jiang, Qing-Hua Wang, Lei Zhang, Shao-Gui Wan, Hong-Ping Chen, 113-121 ... Cytological effects of pulsed electromagnetic fields and static magnetic fields induced by a therapeutic device on in vivo exposed rats · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  18. Collaborative Research: Neutrinos and Nucleosynthesis in Hot and Dense Matter

    Energy Technology Data Exchange (ETDEWEB)

    Alford, Mark [Washington Univ., St. Louis, MO (United States)

    2015-05-31

    The Topical Collaboration funded one of Prof. Alford's graduate students, Jun (Sophia) Han, by providing 75% of her support. The work reported here was wholly or partly supported by the Topical Collaboration. Additional support, e.g. for postdoc Kai Schwenzer, came from Nuclear Theory grant #DE-FG02-05ER41375.

  19. Twee aardbewings of een? Die assosiasie van literêre motiewe in ...

    African Journals Online (AJOL)

    Net soos in die Matteus-evangeiie self, is hier geen duidelike aanduiding van 'n on- derlinge verband tussen die aardbewing en die ander verskynsels wat vermeld word nie. Sintaktiese merkers ontbreek, want die passasie bevat bloot vier frases wat asindeties op mekaar volg, plus een frase wat met 'n neweskikkende Kai ...

  20. Anonimiteit en pseudonimiteit van Bybelse geskrifte

    African Journals Online (AJOL)

    (ou gar de) deur Teopompus geskryf was nie. Hy ontmasker ook die fiktiewe aard van die aanklagte en beswaddering (tas diabolas kai tas loidorias, hais kegreutai tines). 'n Ander voorbeeld van geidentifiseerde vervalsings is die traktate wat die neo-Pitagoreërs aan hulle leermeester toegeskryf het, eeue na sy dood (kyk ...

  1. Üllatav seiklusfantaasia Soomest / Alar Niineväli

    Index Scriptorium Estoniae

    Niineväli, Alar

    2006-01-01

    Soome ja Hiina mütoloogiat ühendav fantaasiafilm "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina, Hollandi ja Eesti ühistöö) : režissöör Antti-Jussi Annila : võitluskunstide koreograaf Yu Yan Kai : osades Tommi Eronen, Zhang Jingchu, Elle Kull. Lisa "Soome film sai Hiinas hea lepingu

  2. The interpretation and translation of galatians 5:12 | Tolmie | Acta ...

    African Journals Online (AJOL)

    As is evident from commentaries on Galatians and from various English translations, scholars do not agree on the meaning, rhetorical labelling and translation of the wish expressed by Paul in Galatians 5:12 ( [Ofelon kai; ajpokovyontai oiJ ajnastatou` nte” uJma`”). In this article various interpretations of this verse are ...

  3. Browse Title Index

    African Journals Online (AJOL)

    Items 51 - 100 of 1309 ... Li-Long Liu, Kai Xu, Lu-Mei Kang, Shu-Ping Jiang, Qing-Hua Wang, ... CR Sewani-Rusike, JE Iputo, EJ Ndebia, M Gondwe, DR Kamadyaapa ... K-M Man, W-C Chen, H-M Wang, H-Y Chen, J-L Shen, L-D Chen, F-J Tsai, ...

  4. Reformierakond naudib ülisuurt toetust / Agnes Kuus

    Index Scriptorium Estoniae

    Kuus, Agnes

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 15. mai 2007, lk. 3. Uuringufirma TSN Emor korraldatud küsitluse kohaselt oli Reformierakonna toetus pärast pronkssõduri sündmusi 46%. Diagramm: Toetus parlamendierakondadele. Kommenteerivad: Kadri Must, Marek Strandberg, Jaanus Marrandi, Margus Tsahkna, Eiki Nestor. Vt. samas: Kai Kalamees. Võimupartnerid usuvad endasse

  5. Georgi söögituba Kotli majas / Helju Koger

    Index Scriptorium Estoniae

    Koger, Helju, 1943-

    2006-01-01

    Georg Lurichi järgi nime saanud söögitoast arhitekt Alar Kotli vanaisale kuulunud hoones Väike-Maarjas. Enne renoveerimist koliti hoone teise kohta. Söögitoa kujunduse tegi Kai Tort, mööbli valmistasid kohalikud puusepad, plekist lambid - Ilmar Aasumets. Omanik Avo Part. 7 värv. ill

  6. Big and small women facing small culture / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    1999-01-01

    Feministlik kunst Eestis alates 1994. aastast. Näitustest EST. FEM, Kood-eks, Private Views. Videod. Fotoinstallatsioonid. Tuntumad kunstnikud: Mare Tralla, Ene-Liis Semper, Mari Laanemets, Eve Kiiler, Tiina Tammetalu, Kai Kaljo, Ly Lestberg, Liina Siib jt. Kunstnike rühmitused: F.F.F.F. Teemad: ema, väike naine, keha. 6 illustratsiooni

  7. Publikum svinger den retoriske taktstok

    DEFF Research Database (Denmark)

    Hansen, Jette Barnholdt

    2012-01-01

    Artiklen handler om revyvisen "Man binder os på mund og hånd" af Poul Henningensen med musik af Kai Normann Andersen, som oprindeligt var en del af den kulturradikale revykomedie Dyveke fra 1940, der bla. advokerede for seksuel frigørelse. Visen levede dog hurtigt sit eget liv uden for revyteatret...

  8. A comparative survey of the condition of tourism infrastructure in Iranian provinces using VIKOR and TOPSIS

    OpenAIRE

    Moslem Bagheri; Payam Shojaei; Maryam Tayebi Khorami

    2018-01-01

    Tourism infrastructure development in different regions of the world does not follow a symmetrically equal pattern. Because of the importance of infrastructure in the tourism development, the present research is an attempt to examine the hard elements of tourism infrastructure in different provinces of Iran, using the indicators proposed by Pearce and Wu (2015) [Pearce, P. L. & Wu, M. Y. (2015). Soft infrastructure at tourism sites: identifying key issues for Asian tourism from case studies. ...

  9. Yi lin cuo yao(Essentials of Medical Works) and its historical materials of medical exchanges between China and Korea%朝鲜《医林撮要》所载中朝医学交流史料研究

    Institute of Scientific and Technical Information of China (English)

    梁永宣

    2001-01-01

    由朝鲜内医郑正先撰、杨礼寿校正,成书于16~17世纪时期的《医林撮要》一书,共13卷128门,它引用了大量李朝前期的朝鲜医书及当时已成书的中国医书资料,是一部非常切合临床应用的综合性方书。特别是书中所收载的“中朝质问方”和“中朝传习方”中的方剂,若干处与中国宋代医书《仁斋直指方论》等有诸多联系,是中国和朝鲜医学交流过程中的重要记录。但它与记载中朝两国政府官员之间医学质问的傅懋光《医学疑问》毫不相关。%Yi lin cuo yao,including 13 chapters and 128 categories,was written by Zheng Zhengxian and collated by Yang Lishou,both Korean imperial physicians in the 16-17th centuries.With notation of a number of the Chinese and Korean medical books and materials in the first decade of the Li dynasty,this book is a comprehensive prescription work,very useful to clinical application.Especially with several points of the formulas from Zhong chao zhi wen fang (Sino-Korean Prescriptions of Questioning) and zhong chao chuan xi fang (Sino-Korean Prescriptions of Questioning) recorded in this book connected with Ren zhai zhi zhi fang lun (Renzhai's Comprehensive Prescriptions) in the Song dynasty.This book is an important record of the exchanges on medical ideas between China and Korea.However,it has nothing to do with Yi xue yi wen (Questions on Medicine) by Fu Maoguang,which records the questions and answers between Chinese and Korean officials.

  10. Comparisons of pharmacokinetic and tissue distribution profile of four major bioactive components after oral administration of Xiang-Fu-Si-Wu Decoction effective fraction in normal and dysmenorrheal symptom rats.

    Science.gov (United States)

    Liu, Pei; Li, Wei; Li, Zhen-hao; Qian, Da-wei; Guo, Jian-ming; Shang, Er-xin; Su, Shu-lan; Tang, Yu-ping; Duan, Jin-ao

    2014-07-03

    Xiang-Fu-Si-Wu Decoction (XFSWD) has been widely used to treat primary dysmenorrhea in clinical practice for hundreds of years and shown great efficacy. One fraction of XFSWD, which was an elution product by macroporous adsorption resin from aqueous extract solution with 60% ethanol (XFSWE), showed great analgesic effect. The present study was conducted to investigate the possible pharmacokinetic and tissue distribution profiles of four major bioactive constituents (berberine, protopine, tetrahydrocoptisine and tetrahydropalmatine) after oral administration of XFSWE in dysmenorrheal symptom rats, and to compare the difference between normal and dysmenorrheal symptom rats. Estradiol benzoate and oxytocin were used to produce dysmenorrheal symptom rat model. The experimental period was seven days. At the final day of experimental period, both normal and dysmenorrheal symptom rats were orally administrated with XFSWE, and then the blood and tissues samples were collected at different time points. Berberine, protopine, tetrahydrocoptisine and tetrahydropalmatine in blood and tissue samples were determined by LC-MS/MS. Pharmacokinetic parameters were calculated from the plasma concentration-time data using non-compartmental methods. The differences of pharmacokinetic parameters among groups were tested by one-way analysis of variance (ANOVA). There were statistically significant differences (Pnormal and dysmenorrheal symptom rats that orally administered with same dosage of XFSWE. In tissue distribution study, the results showed that the overall trend was C(Spleen)>C(Liver)>C(Kidney)>C(Uterus)>C(Heart)>C(Lung)>C(Ovary)>C(Brain)>C(Thymus), C(M-60 min)>C(M-120 min)>C(M-30 min)>C(C-60 min)>C(C-120 min)>C(C-30 min). The contents of protopine in liver, spleen and uterus were more than that in other tissues of dysmenorrheal symptom rats. Compared to normal rats, partial contents of the compounds in dysmenorrheal symptom rats׳ tissues at different time points had significant

  11. Structural basis for corepressor assembly by the orphan nuclear receptor TLX

    OpenAIRE

    Zhi, Xiaoyong; Zhou, X. Edward; He, Yuanzheng; Searose-Xu, Kelvin; Zhang, Chun-Li; Tsai, Chih-Cheng; Melcher, Karsten; Xu, H. Eric

    2015-01-01

    The orphan nuclear receptor TLX regulates neural stem cell self-renewal in the adult brain and functions primarily as a transcription repressor through recruitment of Atrophin corepressors, which bind to TLX via a conserved peptide motif termed the Atro box. Zhi et al. report crystal structures of the human and insect TLX ligand-binding domain in complex with Atro box peptides. Mutations that weaken the TLX–Atrophin interaction compromise the repressive activity of TLX. In addition, mutations...

  12. USSR Report, Life Sciences, Biomedical and Behavioral Sciences, No. 38.

    Science.gov (United States)

    1983-07-22

    However, in the last few years a few of these factories have begun to have problems. After getting all sorts of good food, the chickens are begin...ning to fail and get sick. This is an extremely pressing problem today, being studied by different specialists. I think the major problem here is...34Ispol’zovaniye Proteina Kormov Zhi- votnymi" _/Utilization of Feed Protein by Animals/, Moscow, 1979, pp 123- 141. 43. Kale, K. ,_in the book

  13. Myometrial invasion and overall staging of endometrial carcinoma: assessment using fusion of T2-weighted magnetic resonance imaging and diffusion-weighted magnetic resonance imaging

    OpenAIRE

    Guo, Yu; Wang, Ping; Wang, Penghui; Gao, Wei; Li, Fenge; Yang, Xueling; Ni, Hongyan; Shen, Wen; Guo, Zhi

    2017-01-01

    Yu Guo,1,2 Ping Wang,2 Penghui Wang,2 Wei Gao,1 Fenge Li,3 Xueling Yang,1 Hongyan Ni,2 Wen Shen,2 Zhi Guo1 1Department of Interventional Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin, 2Department of Radiology, Tianjin First Center Hospital, The First Central Clinical College of Tianjin Medical University,...

  14. Seroprevalence of Infections with Dengue, Rift Valley Fever and Chikungunya Viruses in Kenya, 2007.

    Directory of Open Access Journals (Sweden)

    Caroline Ochieng

    Full Text Available Arthropod-borne viruses are a major constituent of emerging infectious diseases worldwide, but limited data are available on the prevalence, distribution, and risk factors for transmission in Kenya and East Africa. In this study, we used 1,091 HIV-negative blood specimens from the 2007 Kenya AIDS Indicator Survey (KAIS 2007 to test for the presence of IgG antibodies to dengue virus (DENV, chikungunya virus (CHIKV and Rift Valley fever virus (RVFV.The KAIS 2007 was a national population-based survey conducted by the Government of Kenya to provide comprehensive information needed to address the HIV/AIDS epidemic. Antibody testing for arboviruses was performed on stored blood specimens from KAIS 2007 through a two-step sandwich IgG ELISA using either commercially available kits or CDC-developed assays. Out of the 1,091 samples tested, 210 (19.2% were positive for IgG antibodies against at least one of the three arboviruses. DENV was the most common of the three viruses tested (12.5% positive, followed by RVFV and CHIKV (4.5% and 0.97%, respectively. For DENV and RVFV, the participant's province of residence was significantly associated (P≤.01 with seropositivity. Seroprevalence of DENV and RVFV increased with age, while there was no correlation between province of residence/age and seropositivity for CHIKV. Females had twelve times higher odds of exposure to CHIK as opposed to DENV and RVFV where both males and females had the same odds of exposure. Lack of education was significantly associated with a higher odds of previous infection with either DENV or RVFV (p <0.01. These data show that a number of people are at risk of arbovirus infections depending on their geographic location in Kenya and transmission of these pathogens is greater than previously appreciated. This poses a public health risk, especially for DENV.

  15. On a Quest for English

    Science.gov (United States)

    Waters, John K.

    2007-01-01

    This article reports the potential of online role-playing games to be a powerful tool for English as a second language (ESL) learning. When Professor Edd Schneider and game designer Kai Zheng suggested to attendees gathered in San Francisco last spring for the annual Game Developers Conference that massively multiplayer online role-playing games,…

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Lei He. Articles written in Journal of Biosciences. Volume 39 Issue 1 March 2014 pp 63-74 Articles. Screening of cellular proteins that interact with the classical swine fever virus non-structural protein 5A by yeast two-hybrid analysis · Chengcheng Zhang Lei He Kai Kang Heng Chen ...

  17. Käsitöö teeb asjad paremaks / Karin Paulus

    Index Scriptorium Estoniae

    Paulus, Karin, 1975-

    2007-01-01

    Eesti ja inglise kunstnike ühisnäitusest "Minu maailm : uus subjektiivsus kaasaegses disainis" Eesti Tarbekunsti- ja Disainimuuseumis. Kuraatorid Emily Campell, Andree Cook, Kai Lobjakas. Eksponeeritakse Annike Laigo, Krista Leesi, Ülle Jehe, Kärt Ojavee töid. Inglismaad esindavad 7 kunstnikku, lähemalt Danny Browni ja Alison Willoughby töödest

  18. Eesti goes St. Etienne / Anna Roomet

    Index Scriptorium Estoniae

    Roomet, Anna

    2006-01-01

    Näitus Eesti Kunstiakadeemia tootedisaini osakonna magistrantide viimase kahe aasta projektide paremikust esindas Eestit disainibiennaalil St. Etiennis Prantsusmaal. Näituse panid üles Pent Talvet ja Pavel Sidorenko, näitusel osalejad: Anna-Maria Einla, Kätlin Kangur, Triin Kuusler, Andri Laidre, Veiko Liis, Liina-Kai Raivet, P. Sidorenko, P. Talvet, Ingela Viks, Triin Voss

  19. Exploration of the factor structure of the Kirton Adaption-Innovation Inventory using bootstrapping estimation.

    Science.gov (United States)

    Im, Subin; Min, Soonhong

    2013-04-01

    Exploratory factor analyses of the Kirton Adaption-Innovation Inventory (KAI), which serves to measure individual cognitive styles, generally indicate three factors: sufficiency of originality, efficiency, and rule/group conformity. In contrast, a 2005 study by Im and Hu using confirmatory factor analysis supported a four-factor structure, dividing the sufficiency of originality dimension into two subdimensions, idea generation and preference for change. This study extends Im and Hu's (2005) study of a derived version of the KAI by providing additional evidence of the four-factor structure. Specifically, the authors test the robustness of the parameter estimates to the violation of normality assumptions in the sample using bootstrap methods. A bias-corrected confidence interval bootstrapping procedure conducted among a sample of 356 participants--members of the Arkansas Household Research Panel, with middle SES and average age of 55.6 yr. (SD = 13.9)--showed that the four-factor model with two subdimensions of sufficiency of originality fits the data significantly better than the three-factor model in non-normality conditions.

  20. Development of a General Conceptual-numerical Model to Simulate the Fate and Subsurface Transport of Explosives, and the Moisture and Temperature Signatures Around Land Mines

    Science.gov (United States)

    2008-12-01

    Chen, J. Gan, J. Šimůnek, A. C. Chang, and L. Wu, Leaching risk of N-nitrosodimethylamine ( NDMA ) in soil receiving reclaimed wastewater, Highlighted...Abstracts, published on a CD-ROM as abstract 5043, ASA, Madison, 2005. Haruta, S., J. Gan, and J. Šimunek, Numerical Analyses of NDMA Leaching Risk in...Gan, J. Šimůnek, A. C. Chang, and L. Wu, Leaching risk of N- nitrosodimethylamine ( NDMA ) in soil receiving reclaimed wastewater, Highlighted article

  1. New species and new records of Amphinemurinae (Plecoptera: Nemouridae) from Shaanxi Province of China.

    Science.gov (United States)

    Li, Weihai; Dong, Wenbin; Yang, Ding

    2018-03-27

    Three new species of the Amphinemurinae genus Amphinemura, A. dicroidea sp. nov., A. longihamita sp. nov. and A. microhamita sp. nov., are described from China. These new species are compared with related taxa. Amphinemura multispina (Wu) and Sphaeronemoura grandicauda (Wu) (also belonging to the Amphinemurinae) are recorded from Shaanxi Province, northwestern China for the first time. The adult male of A. multispina is redescribed and the adult female of S. grandicauda is also described based on new material.

  2. Developing institutional collaboration between Wageningen University and the Chinese Academy of Agricultural Sciences

    OpenAIRE

    Bonnema, A.B.; Lin, Zhai; Qu, Liang; Jacobsen, E.

    2006-01-01

    Scientific co-operation between the Chinese Academy of Agricultural Sciences (CAAS) and Wageningen University (WU) has been underway since 1990, especially in the field of plant sciences. In 2001, CAAS and WU initiated a formal joint PhD training programme to further structure their co-operation. The goals of this co-operation are to: (1) initiate long-term institutional collaboration through capacity building; (2) jointly establish a modern laboratory; (3) jointly develop a cross-cultural sc...

  3. People’s Republic of China Scientific Abstracts, Number 185

    Science.gov (United States)

    1978-02-14

    CONTENTS PAGE HANG-K’UNG CHIH-SHIH [AERONAUTICAL KNOWLEDGE] No 10, October 1977 .... 1 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 3, September 1977 8...launch units; 3) Chairman Hua visiting an earthquake damaged region; 4) a group of female pilots of a minority race. 3012 CSO: 4009 ACTA BOTANICA ...CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICä] in Chinese Vol 19 No 3, Sep 77 pp 167-171 TEXT OF ENGLISH ABSTRACT: 1. The process of microsporogenesis

  4. Enhanced Performance & Functionality of Tunable Delay Lines

    Science.gov (United States)

    2012-08-01

    Based Tunable Optical Delays”, Optics Letters, Vol. 33, Issue 13, pp. 1518-1520 (2008). 2. Louis Christen, Irfan Fazal , Omer F. Yilmaz, Xiaoxia Wu...2008. 3. Omer F. Yilmaz, Louis Christen, Xiaoxia Wu, Scott R. Nuccio, Irfan Fazal , and Alan E. Willner, “Time-Slot-Interchange of 40 Gb/s Variable...F. Yilmaz, S. Khaleghi, L. Christen, I. Fazal , and A. E. Willner, “503 ns, Tunable Optical Delay of 40 Gb/s RZ-OOK using Additional λ-Conversion

  5. 日清戦争後中国女子教育普及に向けた日本教育界の働きかけ : 呉汝綸の日本教育視察(1902)をめぐって

    OpenAIRE

    董, 秋艶; Dong, QiuYan

    2013-01-01

    This paper analyzes the intervention by Japanese educators to spread women's education in China that followed Wu Rulun's observation in Japan. Japanese educators used this opportunity to attempt to introduce Japanese influences into Chinese women's education in the post Sino-Japan War era. Wu made a trip to Japan in order to observe Japanese education and to develop ideas for pending reforms on Chinese women's education. Chapter one reports the Ministry of Education, Science and Culture showi...

  6. Response to Niklasson's comment on Lin, et al. (2012) : "the relation between postural movement and bilateral motor integration".

    Science.gov (United States)

    Lin, Chin-Kai; Kuo, Bor-Chen; Wu, Huey-Min

    2014-10-01

    In the study of Lin, Wu, Lin, Wu, Wu, Kuo, and Yeung (2012 ), the relationship between the validity of postural movement and bilateral motor integration in terms of sensory integration theory was examined. Postural movement is the ability to use the antigravity postures required for stabilization of the neck, trunk and upper extremities via muscle co-contractions in the neck and upper extremities, and balance. Niklasson's (2013 ) comment argued that postural movement should include primitive reflexes in terms of the general abilities approach. Niklasson (2013 ) focused on the efficacy of the treatment rather than the theoretical frameworks implied in the therapeutic activities. For that purpose Lin, et al. (2012 ) used sensory integration as the theoretical foundation, and the relationship between postural movement and bilateral motor integration was assessed via empirical data. The result of Lin, et al. (2012 ) was offered as a theoretical reference for therapeutic activities.

  7. Kant's Categorical Imperative and Mou Zongsan's De Xing Zhi Zhi%牟宗三的德性之知与康德的绝对命令

    Institute of Scientific and Technical Information of China (English)

    刘晓民

    2013-01-01

    康德认为人不能有智的直觉,而牟宗三借用康德的智的直觉的观念,印证了在中国哲学中人是有智的直觉的.牟宗三在其著作中对康德的哲学进行了批判,认为康德哲学的缺陷在于隔离了本体和存在.然而,康德哲学和牟宗三笔下的中国哲学互有长处,没有孰优孰劣.

  8. Readout of the UFFO Slewing Mirror Telescope to detect UV/optical photons from Gamma-Ray Bursts

    DEFF Research Database (Denmark)

    Kim, J. E.; Lim, H.; Nam, J. W.

    2013-01-01

    plane detector of Intensified Charge-Coupled Device (ICCD). The ICCD is sensitive to UV/optical photons of 200–650 nm in wavelength by using a UV-enhanced S20 photocathode and amplifies photoelectrons at a gain of 104–106 in double Micro-Channel Plates. These photons are read out by a Kodak KAI-0340...

  9. Homme kell 18 avatakse Villa Manini kaasaja kunsti keskuses...

    Index Scriptorium Estoniae

    2004-01-01

    Uue Euroopa foto- ja videokunstinäitus "Instant Europe", kus on väljas kümne hiljaaegu Euroopa Liitu astunud riigi - Küpros, Eesti, Läti, Leedu, Malta, Poola, Tšehhi, Slovakkia, Sloveenia, Ungari - kunstnike tööd. Kuraatorid Francesco Bonami ja Sarah Cosulich Canarutto. Eestit esindavad Jaan Toomik, Kai Kaljo, Ene-Liis Semper ja Liina Siib

  10. The Impact of an Assurance System on the Quality of Teaching and Learning--Using the Example of a University in Russia and One of the Universities in Germany

    Science.gov (United States)

    Szymenderski, Peggy; Yagudina, Liliya; Burenkova, Olga

    2015-01-01

    In this paper we consider the question of how quality assurance can have a real, positive impact on the quality of teaching and learning at universities, considering the realities of different systems--the system of control and the system of quality culture--in using the example of two universities: the KNITU-KAI in Russia and the TU Dresden in…

  11. Kofi Annan tahab kõnelusi Kosovo lõppstaatuse üle / Krister Paris

    Index Scriptorium Estoniae

    Paris, Krister, 1977-

    2005-01-01

    Kuni pole selge, milline staatus Kosovot tulevikus ootab, ei ole välisettevõtted huvitatud pikaajaliste investeeringute tegemisest selles piirkonnas. ÜRO eriesindaja Kai Eide raporti kohaselt on Kosovo teinud märkimisväärseid edusamme, kõnelused Kosovo tulevase staatuse üle võiksid alata juba sel aastal. Lisa: Läbirääkijate kolm tingimust

  12. Lin-Na and Yong-Xiu Afr J Tradit Complement Altern Med. (2014) 11 ...

    African Journals Online (AJOL)

    cadewumi

    Evaluation of anti-athletic fatigue activity of Schizandra chinensis aqueous extracts in mice. Afr J Pharm Pharmacol 3: 593-597. 4. Cao, Y., Hu, Y., Liu, P., Zhao, H.X., Zhou, X.J., and Wei, Y.M. (2012). Effects of a Chinese traditional formula Kai Xin San (KXS) on chronic fatigue syndrome mice induced by forced wheel running ...

  13. Eksistentsi krõbisev videolint / Janar Ala

    Index Scriptorium Estoniae

    Ala, Janar, 1979-

    2010-01-01

    Videokunsti näitus "Kõik saab korda" Kumu Kunstimuuseumis 2. jaanuarini 2011, kuraator Maria-Kristiina Soomre. Osalevad järgmised kunstnikud: Marina Abramović, Eija-Liisa Ahtila, Kai Kaljo, Mike Marshall, Ene-Liis Semper, Santeri Tuori, Guido van der Werve. Pikemalt serbia kunstniku Marina Abramović'i ja soome kunstniku Eija-Liisa Ahtila töödest

  14. Markus 16:1-8 in die konteks van 'n konstniksie van die Markaanse ...

    African Journals Online (AJOL)

    Aangesien ons in die geval van Markus nie oor 'n voorhande bron ter ... geringgeskat word wanneer ons ons die Markaanse gemeentekonteks probeer voorstel nie. Linnemann suggests ... that there must be some control exercised over ..... ëaxai náuxa)v ëaxaxoq Kai návxioi' 8i0kovo(; (Mark 9: 35), dit wil sê as mens.

  15. Nog steeds geslote eredienste? Deel2

    African Journals Online (AJOL)

    gronde berus nie. Verwysende na Johannes 17:21 sê hy dat die kerk altyd die een- heid moet soek en bewaar omdat ons almal lede van dieselfde liggaam is. ...... Munchen: Kai ser. Oosthuizen, A J G [1960] 1978b. Ons kerk, in Van Wyk 1978:31-34. Pannenberg, W 1958. Christlicher Glaube und menschliche Freiheit.

  16. Font Effects of Chinese Characters and Pseudo-Characters on the N400: Evidence for an Orthographic Processing View

    Science.gov (United States)

    Lv, Caixia; Wang, Quanhong

    2012-01-01

    Event-related brain potentials (ERPs) were recorded during a Chinese character decision task to examine whether N400 amplitude is modulated by stimulus font. Results revealed large negative-going ERPs in an N400 time window of 300-500 ms to stimuli presented in degraded Xing Kai Ti (XKT) font compared with more intact Song Ti (ST) font regardless…

  17. "Interstanding 3"

    Index Scriptorium Estoniae

    1999-01-01

    25. nov.-st Rotermanni soolalaos rahvusvaheline meediakunsti festival 'Interstanding 3' 'Beyond the Edge ئ Ülalpool piire'. Kuraator Ando Keskküla. Loetletud näitusel osalejad. Eestit esindavad Kai Kaljo, Kiwa, Marko Laimre, Mare Tralla. 26. ja 27. XI Rotermanni soolalaos toimuval konverentsil esinejad, ettekanded. Konverentsi kureerib Eric Kluitenberg Hollandist. Korraldajad: Eesti Kunstiakadeemia, Kaasaegse Kunsti Eesti Keskus.

  18. Uued professorid ja audoktorid

    Index Scriptorium Estoniae

    2009-01-01

    TÜ nõukogu valis rahvusvahelise õiguse professoriks Lauri Mälksoo, peremeditsiini professorik Ruth Kalda, spordipsühholoogia professoriks Lennart Raudsepa; audoktoriteks nimetati EELK peapiiskop Andres Taul, Groningeni ülikooli prof. Cornelius Theodor Hasselblatt, Tampere ülikooli emeriitprof. Kai Krohn, Hollandi Erasmuse Ülikooli prof. Frank G. Grosveld, Suurbritannia Sussexi ülikooli prof. George Nicholas von Tunzelmann

  19. Rapsist diislikütus : kallis ja tõrjutud / Heiki Raudla

    Index Scriptorium Estoniae

    Raudla, Heiki, 1975-

    2008-01-01

    Paldiski Lõunasadamas avatud Biodiesel Paldiski AS tehas loodab tulevikus täisvõimsuse juures toota 100 000 tonni biodiislikütust aastas, praegu eksporditakse kogu toodang peamiselt Lääne-Euroopasse ja Skandinaaviasse. Eesti tarbijale biodiislikütuse tootmist takistab peamiselt tooraine kõrge hind ning vähene nõudlus. Küsimusele vastavad Kai Realo ja Indrek Kaju

  20. Kohtusüsteemi reguleerimise probleeme / Kai Kullerkupp

    Index Scriptorium Estoniae

    Kullerkupp, Kai, 1975-

    1997-01-01

    Kohtute pädevuse piiritlemisest, "õigusemõistmisest" kohtunikuks mitteolevate ametnike poolt, kohtute haldusest, kohtunike õiguslikust seisundist ja teenistusjärelevalvest ning kohtutesisesest tööjaotusest

  1. Kaup kai kõrvalt maailma / Kadri Paas

    Index Scriptorium Estoniae

    Paas, Kadri, 1982-

    2008-01-01

    Ilmunud ka: Delovõje Vedomosti 23. juuli lk. 16. Tallinna Sadam investeerib Muuga ja Paldiski lõunasadama tööstusparkide arendamisse paarsada miljoni krooni. Lisa: Number; Panus pidevasse kaubavoogu; Üle 100 hektari tööstusparki

  2. Ines Karu tantsis end raamatusse / Kais Allkivi

    Index Scriptorium Estoniae

    Allkivi, Kais

    2008-01-01

    USAs ilmus raamat kõhutantsust "Kõhutants tähistamas püha naiselikkust" ("Belly Dance Celebrating the Sacred Feminine"). Raamatu autor on Martha Elena Burns. Eestlannadest on raamatus Ines Karu ja tema trupikaaslane Janne Mõistus. Lisaks fakte Ines Karust "Pühendunud tantsule"

  3. Res Publica soolo rikkus tavasid / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2005-01-01

    Riigikogu aseesimeheks valiti Res Publica liige Taavi Veskimägi, nüüd on Riigikogu juhatuses kaks ühe partei liiget. Riigikogu aseesimeheks tagasi valitud Toomas Vareki hinnangul näitab see samm nii Res Publica kogenematust kui ka Eesti poliitilise kultuuri kehva taset

  4. Kai kurie Antano Baranausko verstos Biblijos (pseudoarchaizmai

    Directory of Open Access Journals (Sweden)

    Birutė Kabašinskaitė

    2011-12-01

    Full Text Available (PSEUDOARCHAISMEN IN ANTANAS BARANAUSKAS’ BIBELÜBERSETZUNGZusammenfassungIn seiner Bibelübersetzung (1901–1902; im weiteren BaB genannt verwendet Antanas Baranauskas aus stilistischen Gründen nicht nur die gängigen Archaismen der alten Texte, sondern auch künstliche morphologische Formen, welche den früheren Sprachzustand wiedergeben sollten, wie er nach den alten Texten, den Mundarten und den Erkenntnissen der historisch-vergleichenden Sprachwissenschaft sowie den Hypothesen des Autors rekonstruiert werden kann.Die in BaB vorkommenden durch das Fehlen der Partikel te- sowie die Endungen -ie, -y, -ai charakterisierten Formen des Kupitivs (geidžiamoji nuosaka sind in Anlehnung an ähnliche Formen des Kupitivs und Imperativs der Mundarten und alten Texte gebildet.Auf die Partikel te- hat Baranauskas wahrscheinlich deswegen verzichtet, weil er das ursprüngliche Paradigma des alten Optativs (der bei ihm als geistaikis bezeichnet wird wiederherstellen wollte.Die dreifachen Endungen der Kupitivformen hat der Autor nicht streng mit irgendwelchen konkreten Präsensstämmen verbunden, obwohl die Mundarten und insbesondere die alten Texte ein konsequenteres System aufweisen.Vom Gebrauch in den heutigen Mundarten und alten Texte unterscheidet sich die Vorgehensweise in BaB durch die häufige Verwendung der Formen mit -ai. Hier bekommen eine solche Endung nicht nur die ā-, sondern auch die ina- und sta-Stämme sowie die auf alten Nasalvokal ų + -va- auslautenden Infixpräsentien. Vorbild für die Formen auf -ai waren wahrscheinlich die in verschiedenen (besonders žemaitischen Mundarten vorkommenden Formen der 3. Person Indikativ Präsens auf -ai mit vorausgestellter Partikel, die in der Funktion des Kupitivs gebraucht werden können. Zur Bevorzugung der Formen auf -ai konnte die Angabe in Schleichers Grammatik veranlaßt haben, daß -ai der ursprüngliche (baltoslavische? Ausgang des Optativs gewesen sei.Ungewöhnlich und höchstwahrscheinlich künstlich sind in BaB die reflexiven Kupitivformen. Bei ihnen findet sich hier der Ausgang -ys(i (ob dieser auch bei ā-Stämmen Verwendung fand, ist schwer zu beurteilen – es waren keine entsprechenden Beispiele auffindbar. Möglicherweise ist dieser Ausgang verallgemeinert auf Grund von Beispielen wie te álkinis (neben te álkinies DP. ähnlich verhält es sich im Falle des Kupitivs der athematischen Verben. Wohl nach dem Muster altlitauischer Beispiele wie te saugti KN wird einigen athematischen Präsentien die Endung -y (gleichgesetzt mit dem Kupitivausgang der i-Stämme? zugewiesen; aber bei den Formen der 3. Person Präsens auf -st (<-sti wird das übliche -ie oder -ai verwendet, wohl weil sie mit den Formen der sta-Stämme in Verbindung gebracht wurden.Veranlaßt durch das Streben nach künstlicher Wiederherstellung des alten Kupitivparadigmas, kommt in BaB auch die eine oder andere unkorrekte, „analogische“ Form vor, die vom Infinitivstamm aus (twinie, Apsiwilkie oder mit Wechsel der Flexionsklasse (sutwirty; -i statt -ėja gebildet ist.Vorbild für auffällige Formen des Partizip Präsens auf -ti-nt- waren die von einem Teil des Žemaitischen verwendeten umgebildeten Paradigmen athematischer Verben; dort haben die Partizipien öfters einen Stamm auf -ta-nt- (aber neben miegtąs auch miegtįs. In Analogie zum Ausgang der 3. Person Präsens des i-Stämme verallgemeinert der Autor -ti-nt-: nach stovi (Kupitiv stovy – stovįs wurde eiti (eity – eitįs geschaffen.Bei einigen Formen des Dativ Singular der Substantiva verwendet BaB im Anschluß an Daukša und vielleicht nach den Nachbardialekten von Anykščiai die Endung -i der alten i- und Konsonantenstämme. Nach dem Vorbild Daukšas, Sirvydas’ und anderer alten Texte wird in einigen Fällen die pronominale Dativform mi gebraucht.Die Verwendung von -ys als Endung des Nominativ Singular des bestimmten Adjektivs zeigt wahrscheinlich, daß der Autor seinen früheren Plan aufgreift, die Endung mit dem älteren (und auch für einen Teil der Mundarten charakteristischen Ausgang -ys der ia-Stämme zu verbinden. Wie den Briefen zu entnehmen ist, entschloß er sich etwa Mitte 1882, die Nominativ-Singularendung der bestimmten Adjektiva und Partizipien (ebenso die des Superlativs der Adjektiva zum Ausgang -ias der a-Stämme in Beziehung zu setzen, welcher nach seiner Ansicht nur zu -is kontrahiert werden konnte. Beim übersetzen der Bibel kehrte er zum Teil wieder zu seiner in der ersten Hälfte des Jahres 1882 praktizierten Verfahrensweise zurück und verwendete bei den bestimmten Adjektiven die Endung -ys.

  5. Legendaarsed toolid Eesti Rahva Muuseumis / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2005-01-01

    Tartu Kõrgema Kunstikooli mööbliosakonna loodud ja ennistatud mööbli näitus "Mööbel. Uksed. Pööning. Vanad tehnikad ja uus elu" Eesti Rahva Muuseumi näitusemajas. Näha saab Kölni messil auhinnatud Priit Verlini kujundatud istet "Allegro", esemeid Leonhard Vene ajaloolise mööbli kogust, Viini mööblikujundaja Koloman Moseri "dr Z-le" loodud ja Tartu ekspertide poolt restaureeritud tooli

  6. Monographs in Tang Official Historiography: Perspectives from the Technical Treatises of the History of Sui (Sui shu)

    OpenAIRE

    Morgan, Daniel Patrick; Chaussende, Damien

    2018-01-01

    Finished in 656 as part of a larger project, the ten ‘treatises’ (zhi) of the current History of Sui (Sui shu) provide us with histories of such fields of technical knowledge as astronomy, astrology, omenology, economics, law, geography, metrology, and library science covering the five divided and short-lived dynasties, 502–618 CE, that were the predecessors of the Tang. This edited volume brings together young experts in these fields to reflect upon the way that their history has been writte...

  7. Solute carrier transporters: potential targets for digestive system neoplasms

    OpenAIRE

    Xie, Jing; Zhu, Xiao Yan; Liu, Lu Ming; Meng, Zhi Qiang

    2018-01-01

    Jing Xie,1,2 Xiao Yan Zhu,1,2 Lu Ming Liu,1,2 Zhi Qiang Meng1,2 1Department of Integrative Oncology, Fudan University Shanghai Cancer Center, 2Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, People’s Republic of China Abstract: Digestive system neoplasms are the leading causes of cancer-related death all over the world. Solute carrier (SLC) superfamily is composed of a series of transporters that are ubiquitously expressed in organs and tissues o...

  8. People’s Republic of China Scientific Abstracts No. 164.

    Science.gov (United States)

    1977-02-23

    of these articles. CONTENTS PAGE K’ O-HSUEH SHIH-YEN /SCIENTIFIC EXPERIMENT/ No 8, Äug 76 1 CHIH-WU HSUEH-PAO /ÄCTA BOTANICA SINICA/ Vol 18, No...AUTHOR: None ORG: Digital Control Teaching Group, Shanghai Sparetime Industrial University TITLE: "On the Principles of Digital Machine Tool Control...8217 College" SOURCE: Peking CHIH-WU HSUEH-PAO [AGTA BOTANICA SINICA] Vol 18 No 3, Sep 76 pp 198-201 EXCERPT OF ENGLISH ABSTRACT: The May-7 Agricultural

  9. People’s Republic of China Scientific Abstracts No. 180

    Science.gov (United States)

    1977-11-25

    translations of these articles. CONTENTS PAGE CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 1, March 1977 1 K’UN-CH’UNG HSUEH-PAO [ACTA ENTOMOLOGICA...March 1977. 28 TUNG-WU HSUEH-PAO [ACTA ZOOLOGICA SINICA] No 2, June.1977 41 a - [III - CC - 70 S § T] ACTA BOTANICA SINICA AUTHOR...HSUEH-PAO [ACTA BOTANICA SINICA] in Chinese Vol 19 No 1, Mar 77 pp 7-10 TEXT OF ENGLISH ABSTRACT: In 1964, we some young teachers and students in

  10. MATHEMATICS OF SENSING, EXPLOITATION, AND EXECUTION (MSEE) Sensing, Exploitation, and Execution (SEE) on a Foundation for Representation, Inference, and Learning

    Science.gov (United States)

    2016-07-01

    Automation (ICRA), 2016. [50]. Y. Lu, S.C. Zhu and Y.N. Wu, Learning FRAME Models Using CNN Filters, 30th AAAI Conference on Artificial Intelligence ...Method Cross-Subject Cross-View Cross-Environment Virtual View 0.507 0.478 0.274 Hankelet 0.542 0.452 0.286 Action Bank 0.246 0.176 N/A Poselet... Intelligence , vol. 34, no.7, 1354-1367, 2012. [3]. N. Jiang, W. Liu and Y. Wu, “Order Determination and Sparsity-Regularized Metric Learning for Adaptive

  11. Traitement du signal à temps continu dans le domaine digital pour des wake-up radios

    OpenAIRE

    Ratiu , Alin

    2015-01-01

    Wake-Up Receivers (WU-RX) have been recently proposed as candidates to reduce the communication power budget of wireless networks. Their role is to sense the environment and wake up the main receivers which then handle the bulk data transfer. Existing WU-RXs achieve very high sensitivities for power consumptions below 50uW but severely degrade their performance in the presence of out-of-band blockers. We attempt to tackle this problem by implementing an ultra low power, tunable, intermediate ...

  12. Batch fermentation of whey ultra filtrate by Lactobacillus helveticus for lactic acid production

    Energy Technology Data Exchange (ETDEWEB)

    Roy, D; Goulet, J; Le Duy, Q

    1986-06-01

    Cheese whey ultrafiltrate (WU) was used as the carbon source for the production of lactic acid by batch fermentation with Lactobacillus helveticus strain milano. The fermentation was conducted in a 400 ml fermentor at an agitation rate of 200 revolutions per minute and under conditions of controlled temperature (42 degrees C) and pH. In the whey ultrafiltrate-corn steep liquor (WU-CSL) medium, the optimal pH for fermentation was 5.9. Inoculum propagated in skim milk (SM) medium or in lactose synthetic (LS) medium resulted in the best performance in fermentation (in terms of growth, lactic acid production, lactic acid yield and maximum productivity of lactic acid), as compared to that propagated in glucose synthetic (GS) medium. The yeast extract ultrafiltrate (YEU) used as the nitrogen/growth factor source in the WU medium at 1.5% (w/v) gave the highest maximum productivity of lactic acid of 2.70 g/l-h, as compared to the CSL and the tryptone ultrafiltrate (TU). 27 references.

  13. People’s Republic of China Scientific Abstracts, Number 201

    Science.gov (United States)

    1978-10-24

    original source materials or information as to the availability of full translations of these articles. CONTENTS PAGE CHIH-WU HSUEH-PAO [ACTA BOTANICA ...III - CC - 70 S § T] ACTA BOTANICA 5INICA AUTHOR: TS’AI Ch’i-kuei (5591 6386 6311 ] CH’IEN Ying-ch’ien [6929 66Q1 0241J CHDU...the Isolation and Culture of Rice (Qrvza sativa L.) Protoplasts" SOURCE: Peking CHIH-WU HSUEH-PA0 [ACTA BOTANICA SINICAj in Chinese No 2, Jun 78 pp

  14. People’s Republic of China Scientific Abstracts, Number 195.

    Science.gov (United States)

    1978-08-01

    76 15 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 1, March 1978 16 TI-CHEN CHAN-HSIEN [EARTHQUAKE FRONT] No 2, April 1978 26 K𔃺-HSUEH...steril^UMs! and Consolidate the contradiction between the hsien and 6168 CSO: 8111/1528 15 ACTA BOTANICA SINICA AUTHOR: CHANG Te-i [l72B 1795...of Cultured Tobacco Cells" SOURCE: Peking CHIH-WU H5UEH-PA0 [_ACTA BOTANICA SINICÄ] in Chinese No 1, Mar 78 pp 1-5 TEXT OF ENGLISH ABSTRACT

  15. A review of the genus Saccharicoccus Ferris, 1950 (Hemiptera: Coccomorpha: Pseudococcidae) in China, with description of a new species.

    Science.gov (United States)

    Zhang, Jiang-Tao; Wu, Bo-Wen; Wu, San-An

    2018-01-23

    The mealybug genus Saccharicoccus Ferris includes three species: S. isfarensis (Borchsenius, 1949), S. sacchari (Cockerell, 1895) and a new species, S. chinensis Zhang, Wu Wu sp. n. The new species, collected on Miscanthus sp. (Poaceae) and other poaceous weeds in China, is described and illustrated, and molecular analyses based on the mitochondrial gene cytochrome c oxidase subunit I (COI) are provided. Additional data on the distribution and host-plants of each species are given, and a key to the adult females of Saccharicoccus species is provided.

  16. Wu’s algorithm and its possible application in cryptanalysis

    CSIR Research Space (South Africa)

    Grobler, TL

    2012-01-01

    Full Text Available now classic book Differential Algebra: Ritt (1950). Later it was independently rediscovered and improved by the Chinese mathematician Wu Wen-Ts?n in the late seventies (Wen-Ts?n, 1978, 1984, 1986). Other resources describing Wu?s algorithm... set that is constructed from a polynomial set so that the characteristic set shares some of the properties of the original set (Gallo and Mishra, 1990b; Ritt, 1950). The algorithm has found wide usage in mechanical theorem proving (Wen-Ts?n, 1986...

  17. Baltimaade klaasikunstil on arenguruumi, vajaka jääb võimalustest / Mare Saare

    Index Scriptorium Estoniae

    Saare, Mare, 1955-

    2008-01-01

    Rahvusvaheline klaasinäitus "Vitrum Balticum IV" ("Balti klaas IV") Kaunases kuni 7. XII. Esindatud on Eesti (Kai Kiudsoo-Värv, Eeva Käsper, Ivo Lill, Kairi Orgusaar, Mare Saare, Maret Sarapu, Tiina Sarapu), Läti, Leedu ja Soome klaasikunstnikud. 14. XI rahvusvaheline seminar Läänemeremaade klaasikunsti arengukäigust 21. sajandil kunstiakadeemias. Näituse ja seminari kuraator kunstiteadlane Raimonda Kogelyte-Simanatiene

  18. Ida-Euroopa kunsti meganäitus Stockholmis

    Index Scriptorium Estoniae

    1999-01-01

    Stockholmi Moodsa Kunsti Muuseumis 16. X 1999-16. I 2000 Kesk- ja Ida-Euroopa kunsti näitus 'After the Wall'. Kuraatorid David Elliott, Bojana Pejic, Iris Müller-Westermann. Eestist osalevad Inessa Josing, Kai Kaljo, Liina Siib, Jaan Toomik. Näituse kataloogis on Jaan Kaplinski ja Heie Treieri artiklid, kataloogile tegid koostööd Johannes Saar, Raoul Kurvitz

  19. Ida-Euroopa kunstnikud koostöövalmis

    Index Scriptorium Estoniae

    2002-01-01

    21. II-31. III Tallinna Kunstihoones Viinis ja Budapestis tegutseva galeristi ja kuraatori Hans Knolli koostatud näitus "An artist who does not speak English is not an artist". Osalevad Lucehezar Boyadijev (Sofia), Aleksandr Brener, Barbara Schurz (Moskva, Viin), Rza El-Hassan (Budapest), Kai Kaljo, Roman Ondák (Bratislava), Mladen Stilinovic (Zagreb), Milica Tomic (Belgrad). Avamisel K. Kaljo performance

  20. "Jade Warrior" kupatab Soome sampo Hiina / Kätlin Kaldmaa

    Index Scriptorium Estoniae

    Kaldmaa, Kätlin, 1970-

    2006-01-01

    Soome ja Hiina mütoloogiat ühendav fantaasiafilm "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina, Hollandi ja Eesti ühistöö) : stsenarist Iiro Küttner : režissöör Antti-Jussi Annila : võitluskunstide koreograaf Yu Yan Kai : osades Tommi Eronen, Zhang Jingchu, Markku Peltola. Lisatud Ave Randviiru, Elle Kulli ja Antti-Jussi Annila "Esimesed muljed"

  1. NCCR Chemical Biology: Interdisciplinary Research Excellence, Outreach, Education, and New Tools for Switzerland.

    Science.gov (United States)

    Sturzenegger, Susi; Johnsson, Kai; Riezman, Howard

    2011-01-01

    Funded by the Swiss National Science Foundation to promote cutting edge research as well as the advancement of young researchers and women, technology transfer, outreach and education, the NCCR (Swiss National Centre of Competence in Research) Chemical Biology is co-led by Howard Riezman, University of Geneva and Kai Johnsson, École Polytechnique Fédérale de Lausanne (EPFL).

  2. Temperature Dependent Rubidium Helium Line Shapes and Fine Structure Mixing Rates

    Science.gov (United States)

    2015-09-01

    tube biased at 1,275 V exhibited a dark signal bias of 4-6 nA with noise fluctuation of 0.04 nA, as monitored on a Keithley model 386 picoammeter with...Journal of Physical Chemistry, 74(1):187–196, 1970. [79] Wu, Sheldon SQ, Thomas F Soules , Ralph H Page, Scott C Mitchell, V Keith Kanz, and Raymond J...Society for Optics and Photonics, 2008. [80] Wu, Sheldon SQ, Thomas F Soules , Ralph H Page, Scott C Mitchell, V Keith Kanz, and Raymond J Beach

  3. Temperature Dependent Rubidium-Helium Line Shapes and Fine Structure Mixing Rates

    Science.gov (United States)

    2015-09-17

    tube biased at 1,275 V exhibited a dark signal bias of 4-6 nA with noise fluctuation of 0.04 nA, as monitored on a Keithley model 386 picoammeter with...Journal of Physical Chemistry, 74(1):187–196, 1970. [79] Wu, Sheldon SQ, Thomas F Soules , Ralph H Page, Scott C Mitchell, V Keith Kanz, and Raymond J...Society for Optics and Photonics, 2008. [80] Wu, Sheldon SQ, Thomas F Soules , Ralph H Page, Scott C Mitchell, V Keith Kanz, and Raymond J Beach

  4. Stoneflies of the genus Neoperla (Plecoptera, Perlidae from Wuyi Mountain National Nature Reserve, Fujian of China

    Directory of Open Access Journals (Sweden)

    Xue-Feng Qin

    2013-08-01

    Full Text Available The species of the genus Neoperla are reviewed from Wuyi Mountain National Nature Reserve located in the Fujian Province of southeastern China, including the description of a new species, Neoperla brevistyla sp. n. The new species is compared to similar taxa. The first records of five Neoperla species, N. henana Li, Wu & Zhang, 2011, N. similiserecta Wang & Li, 2012, N. qingyuanensis Yang & Yang, 1995, N. xuansongae Li & Li, 2013 and N. tuberculata Wu, 1938 are given for the Wuyi Mountain. A provisional key is provided for facilitating the identification of these species.

  5. Stoneflies of the genus Neoperla (Plecoptera, Perlidae) from Wuyi Mountain National Nature Reserve, Fujian of China.

    Science.gov (United States)

    Qin, Xue-Feng; Murányi, Dávid; Wang, Guo-Quan; Li, Wei-Hai

    2013-01-01

    The species of the genus Neoperla are reviewed from Wuyi Mountain National Nature Reserve located in the Fujian Province of southeastern China, including the description of a new species, Neoperla brevistyla sp. n. The new species is compared to similar taxa. The first records of five Neoperla species, Neoperla henana Li, Wu & Zhang, 2011, Neoperla similiserecta Wang & Li, 2012, Neoperla qingyuanensis Yang & Yang, 1995, Neoperla xuansongae Li & Li, 2013 and Neoperla tuberculata Wu, 1938 are given for the Wuyi Mountain. A provisional key is provided for facilitating the identification of these species.

  6. On the security of a novel probabilistic signature based on bilinear square Diffie-Hellman problem and its extension.

    Science.gov (United States)

    Zhao, Zhenguo; Shi, Wenbo

    2014-01-01

    Probabilistic signature scheme has been widely used in modern electronic commerce since it could provide integrity, authenticity, and nonrepudiation. Recently, Wu and Lin proposed a novel probabilistic signature (PS) scheme using the bilinear square Diffie-Hellman (BSDH) problem. They also extended it to a universal designated verifier signature (UDVS) scheme. In this paper, we analyze the security of Wu et al.'s PS scheme and UDVS scheme. Through concrete attacks, we demonstrate both of their schemes are not unforgeable. The security analysis shows that their schemes are not suitable for practical applications.

  7. Ultrafast Optics: Vector Cavity Laser - Physics and Technology

    Science.gov (United States)

    2016-06-14

    with a quasi- vector cavity both numerically and experimentally. It is expected that through the study a deep and comprehensive understanding on the...799-801, Jun. 1997. 31. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like pulse in a gain-guided soliton fiber laser," Opt...solitons in a ring fiber laser," Optics Communications 281 (22), 5614 (2008). 110. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like

  8. Ultrafast Optics - Vector Cavity Lasers: Physics and Technology

    Science.gov (United States)

    2016-06-14

    with a quasi- vector cavity both numerically and experimentally. It is expected that through the study a deep and comprehensive understanding on the...799-801, Jun. 1997. 31. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like pulse in a gain-guided soliton fiber laser," Opt...solitons in a ring fiber laser," Optics Communications 281 (22), 5614 (2008). 110. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like

  9. Ultrafast Optics: Vector Cavity Fiber Lasers - Physics and Technology

    Science.gov (United States)

    2016-06-14

    with a quasi- vector cavity both numerically and experimentally. It is expected that through the study a deep and comprehensive understanding on the...799-801, Jun. 1997. 31. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like pulse in a gain-guided soliton fiber laser," Opt...solitons in a ring fiber laser," Optics Communications 281 (22), 5614 (2008). 110. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like

  10. Comparison of Three Methods for Generating Superhydrophobic, Superoleophobic Nylon Nonwoven Surfaces (Postprint)

    Science.gov (United States)

    2011-04-01

    film and onto a 100 g/ m2 nylon nonwoven substrate was carried out in a cylindri- cal , inductively coupled plasma reactor (10 cm diameter and 2700 cm3...the Nonwoven Institute (NI) for sharing hydro- entangled nonwoven fabric with us. References 1. Barthlott W, Neinhuis C (1997) Planta 202:1 2. Wu X...Faraday Soc 40:546 8. Lee H (2009) J Mater Sci 44:4645. doi:10.1007/s10853-009- 3711-5 9. Hoefnagels H, Wu D, de With G, Ming W (2007) Langmuir 23

  11. Combined Effects of Primary and Tertiary Blast on Rat Brain: Characterization of a Model of Blast-induced Mild Traumatic Brain Injury

    Science.gov (United States)

    2013-03-01

    injury in U.S. military personnel. N Engl J Med 364, 2091–2100 (2011) 27. Lu J, Ng KC , Ling GS, Wu J, Poon JF, Kan EM, Tan MH, Wu YJ, Li P...Moochhala S, Yap E, Lee LK, Teo AL, Yeh IB, Ser- gio DM, Chua F, Kumar SD, Ling EA: Effect of blast exposure on the brain structure and cognition in the...12689448] 32. Henderson D, Bielefeld EC, Harris KC , Hu BH. The role of oxidative stress in noise-induced hearing loss. Ear Hear. 2006;27(1):1–19. [PMID

  12. Product marketing for eco-power; Produktemarketing fuer Oekostrom

    Energy Technology Data Exchange (ETDEWEB)

    Huber, D. [Verband Schweizerischer Elektrizitaetswerke, Zuerich (Switzerland)

    1998-10-30

    The company NaturEnergie (natural energy), a subsidiary of the Energieversorger Kraftwerk Laufenburg AG (KWL) is located in Grenzach-Whylen (Germany) near Basel (Switzerland) has been selling power generated from sun and water since the 1st of October 1998. The company employes a cleverly designed, emotional marketing strategy in order to position the brand ``NaturEnergie`` as a label for ``green power`` on the market. Bulletin VSE talked to Dr. Kai-Hendrik Schlusche (40), co-founder and member of the board of NaturEnergie AG about marketing and pricing of ``green`` power and about relations with Switzerland.(orig.) [Deutsch] Im grenznahen Grenzach-Whylen bei Basel verkauft die Firma NaturEnergie, eine Tochtergesellschaft der Energieversorger Kraftwerk Laufenburg AG (KWL) und Kraftuebertragungswerke Rheinfelden AG (KWR), seit 1. Oktober 1998 Oekostrom aus Sonne und Wasser. Mit Hilfe einer ausgekluegelten emotionellen Marketingstrategie will das junge Unternehmen die Marke `NaturEnergie` als Label fuer `gruenen Strom` im Markt positionieren. Bulletin VSE sprach mit Dr. Kai-Hendrik Schlusche (40), seit Mai 1998 Gruendungsvorstand der NaturEnergie AG, ueber Marketing, Preisgestaltung von `gruenem Strom` und die Beziehungen zur Schweiz. (orig.)

  13. Effects of Huang Bai (Phellodendri Cortex and Three Other Herbs on GnRH and GH Levels in GT1–7 and GH3 Cells

    Directory of Open Access Journals (Sweden)

    Sun Haeng Lee

    2016-01-01

    Full Text Available The present study was to evaluate the effects of Huang Bai, Zhi Mu, Mai Ya, and Xia Ku Cao on hormone using the GT1–7 and GH3 cells. The GT1–7 and GH3 cell lines were incubated with DW; DMSO; and 30, 100, or 300 μg/mL of one of the four extract solutions in serum-free media for 24 hours. The MTT assay was performed to determine the cytotoxicity of the four herbs. The GT1–7 and GH3 cells were incubated in DW, estradiol (GT1–7 only, or noncytotoxic herb solutions in serum-free medium for 24 hours. A quantitative RT-PCR and western blot were performed to measure the GnRH expression in GT1–7 cells and GH expression in GH3 cells. Huang Bai, Zhi Mu, Xia Ku Cao, and Mai Ya inhibited the GnRH mRNA expression in GT1–7 cells, whereas Huang Bai enhanced GH mRNA expression in GH3 cells. Additionally, Xia Ku Cao inhibited GnRH protein expression in GT1–7 cells and Huang Bai promoted GH protein expression in GH3 cells. The findings suggest that Huang Bai can delay puberty by inhibiting GnRH synthesis in the hypothalamus while also accelerating growth by promoting GH synthesis and secretion in the pituitary.

  14. Lipids as organizers of cell membranes.

    Science.gov (United States)

    Kornmann, Benoît; Roux, Aurélien

    2012-08-01

    The 105th Boehringer Ingelheim Fonds International Titisee Conference 'Lipids as Organizers of Cell Membranes' took place in March 2012, in Germany. Kai Simons and Gisou Van der Goot gathered cell biologists and biophysicists to discuss the interplay between lipids and proteins in biological membranes, with an emphasis on how technological advances could help fill the gap in our understanding of the lipid part of the membrane.

  15. Australian Defence Force Requirements for a Group-feeding Ration Pack

    Science.gov (United States)

    2010-04-01

    Kai Si Ming 2 x 500g Chicken, pasta & veg 2 x 500g Frankfurters 2 x 185g Chicken curry 2 x 500g Sausages & spaghetti 2 x 500g Spaghetti & meatballs 2...Tomato & Onions Spaghetti & Meatballs Sweet Corn None Some All Very Bad Bad Neutral Good Very Good Q.12. go to Q.12. Q.7. On average, how many hours per

  16. Aksara Incung Kerinci Sebagai Sumber Ide Penciptaan Seni Kriya

    OpenAIRE

    Mubarat, Husni

    2015-01-01

    Aksara Incung Kerinci merupakan naskah kuno yang dipakai oleh suku Kerinci pada dahulunya sebagai wahana untuk menulis sastra, hukum adat, dan mantera- mantera yang ditulis pada kulit kayu, tanduk kerbau, bambu dan daun lontar. Aksara Incung digunakan sebagai sumber penciptaan karya. Penciptaan karya ini melalui tiga tahap, yaitu eksplorasi, perancangan, dan perwujudan melalui pencarian bentuk seni kriya yang baru, kreatif, dan inovatif, dengan tidak meninggalkan kaidah-kai...

  17. Sotsiaalselt pime ja poliitiliselt impotentne teater / Alvar Loog

    Index Scriptorium Estoniae

    Loog, Alvar

    2006-01-01

    Poliitilisest ja sotsiaalsest teatrist Eestis 2005. aasta lavastuste põhjal : Pip Upponi "Adolf" Tartu Püssirohukeldris, lavastaja Ervin Õunapuu; Merle Karusoo "Misjonärid" Rakvere Teatris; Alistair Beatoni "Õnnetunne" Ugalas, lavastaja Jaak Allik; Toomas Kalli " Viimane sent" Vana Baskini Teatris, lavastaja Eino Baskin; George Orwelli "Loomade farm" Tallinna Linnateatris, lavastaja Mart Koldits; Kai Henseli "Klammi sõda" VAT Teatris, lavastaja Aare Toikka

  18. Poeetilise utoopia meister Aino Bach

    Index Scriptorium Estoniae

    2003-01-01

    28. III-11. V Adamson-Ericu muuseumis graafik Aino Bachi loomingu ülevaatenäitus. Võrdluseks on eksponeeritud Eduard Wiiralti ja Kaarel Liimandi tööd. Näha võib Mark Soosaare filmi A. Bachist "Liblikapüüdja" (1978). Kuraator Anne Lõugas, kujundaja Virge Jõekalda. Kai Tuviku juhendamisel muuseumitunnid "Kuidas joonistada inimest?". 1. IV seminaril "Naiskunstnik ja tema aeg. Aino Bach" esinejad, ettekanded

  19. Analisis Fitur M-Ticketing PT. Kereta Api Indonesia sebagai Bagian dari Customer Relation Management (CRM)

    OpenAIRE

    Hijrih, Fatchul; Prasetyo, Taufan Harry

    2015-01-01

    Sebagai Perusahaan jasa tranportasi darat yaitu kereta api, PT. Kereta Api Indonesia perlu memperhatikan aspek pelayanan terhadap pelanggan dengan memperhatikan fitur-fitur Customer Relation Management dalam membuat dalam membuat aplikasi-aplikasi yang berhubungan langsung dengan pelanggan, salah satunya m-ticketing. Kemunculan m-ticketing KAI saat ini digunakan sebagai alat penjualan tiket saja. Hal ini dapat terlihat dari menu atau fitur-fitur yang disematkan kedalam aplikasi tersebut. Adan...

  20. Lego clocks: building a clock from parts.

    Science.gov (United States)

    Brunner, Michael; Simons, Mirre J P; Merrow, Martha

    2008-06-01

    A new finding opens up speculation that the molecular mechanism of circadian clocks in Synechococcus elongatus is composed of multiple oscillator systems (Kitayama and colleagues, this issue, pp. 1513-1521), as has been described in many eukaryotic clock model systems. However, an alternative intepretation is that the pacemaker mechanism-as previously suggested-lies primarily in the rate of ATP hydrolysis by the clock protein KaiC.

  1. Tuhkatriinust printsessiks / Heie Treier

    Index Scriptorium Estoniae

    Treier, Heie, 1963-

    1999-01-01

    Ida- ja Kesk-Euroopa 1990ndate kunsti näitus 'Pärast müüri' ('After the Wall') Stockholmis Moderna Museetis. Kureerinud David Elliott, Bojana Pejic, Iris Müller-Westermann. Seminarist. Eesti kunstnike Jaan Toomiku, Kai Kaljo, Liina Siibi, Inessa Josingu esinemisest. Kommenteerivad Moskva kuraator J. Bakstein, rootsi kunstikriitik C. Chambert, makedoonia kuraator S. Milevska, ajakirja NU toimetaja J.-P. Nilsson, New Yorgi kunstikriitik K. Levin

  2. Mathematical modeling and simulation of aquatic and aerial animal locomotion

    Science.gov (United States)

    Hou, T. Y.; Stredie, V. G.; Wu, T. Y.

    2007-08-01

    In this paper, we investigate the locomotion of fish and birds by applying a new unsteady, flexible wing theory that takes into account the strong nonlinear dynamics semi-analytically. We also make extensive comparative study between the new approach and the modified vortex blob method inspired from Chorin's and Krasny's work. We first implement the modified vortex blob method for two examples and then discuss the numerical implementation of the nonlinear analytical mathematical model of Wu. We will demonstrate that Wu's method can capture the nonlinear effects very well by applying it to some specific cases and by comparing with the experiments available. In particular, we apply Wu's method to analyze Wagner's result for a wing abruptly undergoing an increase in incidence angle. Moreover, we study the vorticity generated by a wing in heaving, pitching and bending motion. In both cases, we show that the new method can accurately represent the vortex structure behind a flying wing and its influence on the bound vortex sheet on the wing.

  3. Conjugate heat and mass transfer in heat mass exchanger ducts

    CERN Document Server

    Zhang, Li-Zhi

    2013-01-01

    Conjugate Heat and Mass Transfer in Heat Mass Exchanger Ducts bridges the gap between fundamentals and recent discoveries, making it a valuable tool for anyone looking to expand their knowledge of heat exchangers. The first book on the market to cover conjugate heat and mass transfer in heat exchangers, author Li-Zhi Zhang goes beyond the basics to cover recent advancements in equipment for energy use and environmental control (such as heat and moisture recovery ventilators, hollow fiber membrane modules for humidification/dehumidification, membrane modules for air purification, desi

  4. The effect of calcium infiltration and irradiation treatment on biochemical and physiological aspects during mango storage

    International Nuclear Information System (INIS)

    Deng Qiaobing; Liu Shaode

    1993-01-01

    Zhi Hua Mango (Mangifera indica L.) was treated using calcium infiltration and radiation. Biochemical and physiological aspects during mango storage were researched. The results that the treatment of CaCl 2 with radiation (dose of 0.25 kGy) can retard Malic enzyme activity, and radiation can also cause effects on the transpiration of Ca ++ and release of CO 2 and ethylene. The mango treated with above way is the best one from view of sense organ. However it does not delay maturity of mango to use Ca ++ treatment alone

  5. Traditional Chinese Medicine Improves Activities of Daily Living in Parkinson's Disease

    OpenAIRE

    Pan, Weidong; Kwak, Shin; Liu, Yun; Sun, Yan; Fang, Zhenglong; Qin, Baofeng; Yamamoto, Yoshiharu

    2011-01-01

    We evaluated the effects of a traditional Chinese medicine (TCM), named Zeng-xiao An-shen Zhi-chan 2 (ZAZ2), on patients with Parkinson's disease (PD). Among 115 patients with idiopathic PD enrolled (mean age, 64.7 ± 10.2 years old), 110 patients (M = 65, F = 45; mean age, 64.9 ± 10.7 years old) completed the study. Patients took either ZAZ2 ( = 5 9 ) or placebo granule ( = 5 6 ) in a blind manner for 13 weeks while maintaining other anti-Parkinson medications unchanged. All participants ...

  6. Chinese-English Rocketry Dictionary. Volume 3

    Science.gov (United States)

    1979-03-01

    holder; mount ; brace; am; outri•gger ZhiJu substation ; out station; 11 subcontrol office; suboffice; out office; minor office zhikeceng subehell 12... pad 09 tarthuang’e JrI• M’ spring yoke LU tanhuanggang Vr 4i spring steel 11 Lanhuanggang huomen •T• . S (. P•i sprign-s ,eel shutter 12 tanhuanggong...lead; teadin’. tiqi-an 15,2.am f41 ýi IV1 prnrratin’e detmnation ɞ tiqjita --edJin;1, siijian, 41 i Al ] Jillmdern intLerval tipo -n 6113.r1u 41Ff

  7. 清末民初における『レ・ミゼラブル』の移入と日本 : 陳景韓訳「哀史之一節逸犯」を例として

    OpenAIRE

    梁, 艶; Liang, Yan

    2011-01-01

    Victor Hugo was introduced into China through his Japanese translations. However, the route of the reception of his masterpiece Les Misérables in China has not yet been explained clearly. In this paper, I will take Ai Shi Zhi Yi Jie Yi Fan, a Chinese translation by Chen Jinghan of a part of Les Misérables, as an example to see how Les Misérables was introduced into China. By examining Japanese translations of Les Misérables, I come to the conclusion that Chen was influenced by Kuroiwa Ruikô's...

  8. Global existence of periodic solutions on a simplified BAM neural network model with delays

    International Nuclear Information System (INIS)

    Zheng Baodong; Zhang Yazhuo; Zhang Chunrui

    2008-01-01

    A simplified n-dimensional BAM neural network model with delays is considered. Some results of Hopf bifurcations occurring at the zero equilibrium as the delay increases are exhibited. Global existence of periodic solutions are established using a global Hopf bifurcation result of Wu [Wu J. Symmetric functional-differential equations and neural networks with memory. Trans Am Math Soc 1998;350:4799-838], and a Bendixson criterion for higher dimensional ordinary differential equations due to Li and Muldowney [Li MY, Muldowney J. On Bendixson's criterion. J Differ Equations 1994;106:27-39]. Finally, computer simulations are performed to illustrate the analytical results found

  9. From the transnational to the Sinophone: lesbian representations in Chinese-language films.

    Science.gov (United States)

    Wong, Alvin Ka Hin

    2012-01-01

    This article theorizes global lesbian cinema in Chinese-language films through regionalism, diaspora studies, and Sinophone studies. Through an inter-regional analysis of Butterfly (Yan Yan Mak, 2004, Hong Kong) and diasporic and Sinophone readings of Saving Face (Alice Wu, 2005, USA), I argue that Mak's film illustrates a Hong Kong regional retranslation of a Taiwanese lesbian story, which complicates any claim to a stable "Chinese" identity. Finally, Wu's representation of lesbianism also troubles the politics of Chineseness by pointing to the ways diasporic reproduction of "community" works through the disciplining of other non-normative sexualities.

  10. Five newly recorded Cyprinid fish (Teleostei: Cypriniformes) in Myanmar

    Science.gov (United States)

    Qin, Tao; Chen, Zhi-Ying; Xu, Lu-Lu; Zaw, Paing; Kyaw, Yunn Mi Mi; Maung, Kyaw Win; Chen, Xiao-Yong

    2017-01-01

    Freshwater fish from the Putao and Myitkyina areas were collected in three ichthyofaunal surveys of the Mali Hka River and tributaries in and around Khakaborazi National Park and Hponkanrazi Wildlife Sanctuary, Kachin State, from 2014-2016. Tor yingjiangensis Chen et Yang 2004, Tor qiaojiensis Wu et al. 1977, Garra qiaojiensis Wu et al. 1977, Garra bispinosa Zhang 2005, and Schizothorax oligolepis Huang 1985, originally described from the upper Irrawaddy (Ayeyarwaddy) River in China, are first reported herein as new records to Myanmar. Counts, measurements, descriptions, photographs, and distributions of the specimens of the five newly recorded species are provided. PMID:29181904

  11. Stochastic quantization and gauge-fixing of the linearized gravitational field

    International Nuclear Information System (INIS)

    Hueffel, H.; Rumpf, H.

    1984-01-01

    Due to the indefiniteness of the Euclidean gravitational action the Parisi-Wu stochastic quantization scheme fails in the case of the gravitational field. Therefore we apply a recently proposed modification of stochastic quantization that works in Minkowski space and preserves all the advantages of the original Parisi-Wu method; in particular no gauge-fixing is required. Additionally stochastic gauge-fixing may be introduced and is also studied in detail. The graviton propagators obtained with and without stochastic gauge-fixing all exhibit a noncausal contribution, but apart from this effect the gauge-invariant quantities are the same as those of standard quantization. (Author)

  12. Disaini abil edukaks / Bo Englund ; interv. Kai Lobjakas

    Index Scriptorium Estoniae

    Englund, Bo

    2005-01-01

    Euroopa Disainiühenduste büroost (Bureau of European Design Association - BEDA), rahvuslikust disainipoliitikast, Rootsi-Eesti disainikonverentsist "Innovatsioon läbi disaini - disaini oma tulevik" Viinistu Kunstimuuseumis. Kommentaar Karin Pauluselt

  13. Hansapanga kunstisaal tutvustab Läti kunsti / Kai Vahe

    Index Scriptorium Estoniae

    Vahe, Kai

    2000-01-01

    2000. a. dets. lõpuni oli kunstisaalis avatud läti 5 kunstniku näitus "Distants" - Aija Zarina, Ieva Iltnere, Sarmite Malina, Anita Zabilevska ja Kristaps Gelzis. Väljendavad suhet ümbritsevasse iroonia kaudu

  14. Turule tuleb veel üks arvutipood / Kai Simson

    Index Scriptorium Estoniae

    Simson, Kai

    2004-01-01

    2004. a. detsembri alguses alustas tegevust jaekaubanduskett Enter IT-Market, mille eesmärk on pakkuda kõigis Eesti maakonnakeskustes kodukasutajatele suurimat valikut arvuti- ja digikaupu ühest kohast

  15. Kultuuriruum ja Natalie Mei prostitutsiooniteemalised joonistused / Kai Stahl

    Index Scriptorium Estoniae

    Stahl, Kai

    2011-01-01

    Analüüsitakse feministliku lugemise ja Juri Lotmani kultuurisemiootika abil kultuuri ja "mittekultuuri" vahelist piiriala, keskendudes viisidele, kuidas Natalie Mei erines oma joonistustega kunsti üldpildist - rikkudes traditsionaalset pildikoodi, ironiseerib Mei selle teema domineerivat käsitlust ja pildilist kuvamist, luues naiskunstnikuna uue vaatenurga

  16. E-tervishoiust on abi kõigile / Kai Ilustrumm

    Index Scriptorium Estoniae

    Ilustrumm, Kai

    2004-01-01

    Vt. ka Linnaleht : Pärnu : Tehnika, Linnaleht : Tartu : Tehnika 5. nov., lk. 10. Ida-Tallinna Keskhaigla on haaratud Taani, Norra, Rootsi, Eesti ja Leedu tervishoiualasesse koostööprojekti Baltic eHealth ehk Balti e-tervishoid. Ida-Tallinna Keskhaiglasse rajatakse rahvusvaheline radioloogiakeskus

  17. Noore õpetaja stardiraha tekitab kultuurikomisjonis vaidlusi / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2007-01-01

    24. oktoobril esimese lugemise läbinud eelnõu, mis tagab 2008. aasta 1. septembrist esimest korda koolis tööd alustavatele õpetajatele stardiraha, jõuab uuesti riigikogu ette detsembris. Tallinna Ülikoolis kolmandal kursusel klassiõpetajaks õppiv Helen Tuga seob oma tuleviku õpetajatööga ka ilma riigi antava 200 000 kroonita

  18. Eelarveheitlus sai eile riigikogus vihase avastardi / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2004-01-01

    Ilmunud ka: Infopress, 1. okt. 2004, nr. 40, lk. 24. Peaminister Juhan Partsi kõnest Riigikogus 2005. aasta riigieelarve eelnõu üle andes. Riigikogu liikmete hinnanguid eelarve kohta. Diagrammid: Eelarve jõudis riigikokku. Lisa: Riigi tulud tuleval aastal. Kommenteerivad Eiki Nestor, Ain Seppik, Mart Laar

  19. Kaheksas ehtenäitus sel hooajal / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    1999-01-01

    18. VI-8. VIII Tarbekunstimuuseumis rahvusvaheline ehtekunstinäitus "Meele Avaldus/Mind Seduction". Osalema on kutsutud 30 noort ehtekunstnikku seitsmest Euroopa riigist. Kuraator ja kujundaja Ketli Tiitsar. Eestit esindavad rühmituse F.F.F.F. liikmed, Mari ja Adolfas Shaulys

  20. Lovgoi kai; e[rga : Thucydides and His Speeches

    Directory of Open Access Journals (Sweden)

    Gregor Pobežin

    2006-12-01

    Full Text Available The paper deals with some problems posed by the study of speeches in Thucydides' History of the Peloponnesian War, especially those that result from seeking the so-called historical truth. The historical value of the speeches, which show the unmistakable influence of forensic oratory, has been subject to various interpretations. The efforts seem to be epitomised by the search for an adequate explanation of the so-called “methodological” chapter 1.22, especially the sentence 1.22.1, which has been identified as the most crucial for a proper understanding of Thucydides' use of speeches: wJ~ dÆ a]n ejdovkoun moi e{kastoi peri; tw`n ajei; parovntwn ta; devonta mavlistÆ eijpei`n, ejcomevnw/ o{ti ejgguvtata th`~ xumpavsh~ gnwvmh~ tw`n ajlhqw`~ lecqevntwn, ou{tw~ ei[rhtai . It seems absolutely imperative that this sentence be understood as an authorial manifesto, a statement of the use and arrangement of speeches in the work. To deny the author even the minimum of historical ambition in the speeches included, thus reducing the entire account to a work of largely fictional value, seems highly inadequate. The paper therefore contends that, while there is no actual proof that the speeches available to the reader were recorded in their spoken form (in fact, judging from the term th`~ xumpavsh~ gnwvmh~ , their length may well have been adapted to the needs of a historical narrative, there is similarly no ground for denying their basic historical substance.