Sample records for winneshiek fayette clayton

  1. Fayette County Better Buildings Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Capella, Arthur [County of Fayette, Uniontown, PA (United States)


    The Fayette County Better Buildings Initiative represented a comprehensive and collaborative approach to promoting and implementing energy efficiency improvements. The initiative was designed to focus on implementing energy efficiency improvements in residential units, while simultaneously supporting general marketing of the benefits of implementing energy efficiency measures. The ultimate goal of Fayette County’s Better Buildings Initiative was to implement a total of 1,067 residential energy efficiency retrofits with a minimum 15% estimated energy efficiency savings per unit. Program partners included: United States Department of Energy, Allegheny Power, and Private Industry Council of Westmoreland-Fayette, Fayette County Redevelopment Authority, and various local partners. The program was open to any Fayette County residents who own their home and meet the prequalifying conditions. The level of assistance offered depended upon household income and commitment to undergo a BPI – Certified Audit and implement energy efficiency measures, which aimed to result in at least a 15% reduction in energy usage. The initiative was designed to focus on implementing energy efficiency improvements in residential units, while simultaneously supporting general marketing of the benefits of implementing energy efficiency measures. Additionally, the program had components that involved recruitment and training for employment of persons in the energy sector (green jobs), as well as marketing and implementation of a commercial or community facilities component. The residential component of Fayette County’s Better Buildings Initiative involved a comprehensive approach, providing assistance to low- moderate- and market-rate homeowners. The initiative will also coordinate activities with local utility providers to further incentivize energy efficiency improvements among qualifying homeowners. The commercial component of Fayette County’s Better Building Initiative involved grants

  2. 75 FR 4269 - Establishment of Class E Airspace; Clayton, GA (United States)


    ... September 14, 2009 that establishes Class E Airspace at Heaven's Landing Airport, Clayton, GA. DATES... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0605; Airspace Docket No. 09-ASO-19] Establishment of Class E Airspace; Clayton, GA AGENCY: Federal...

  3. 78 FR 2675 - Revised Jurisdictional Thresholds of the Clayton Act (United States)


    ... FEDERAL TRADE COMMISSION Revised Jurisdictional Thresholds of the Clayton Act AGENCY: Federal... for interlocking directorates required by the 1990 amendment of Section 8 of the Clayton Act. Section..., (202) 326-2879. Authority: 15 U.S.C. 19(a)(5). By direction of the Commission. Richard C. Donohue...

  4. A new Ordovician arthropod from the Winneshiek Lagerstätte of Iowa (USA) reveals the ground plan of eurypterids and chasmataspidids (United States)

    Lamsdell, James C.; Briggs, Derek E. G.; Liu, Huaibao P.; Witzke, Brian J.; McKay, Robert M.


    Euchelicerates were a major component of Palaeozoic faunas, but their basal relationships are uncertain: it has been suggested that Xiphosura—xiphosurids (horseshoe crabs) and similar Palaeozoic forms, the synziphosurines—may not represent a natural group. Basal euchelicerates are rare in the fossil record, however, particularly during the initial Ordovician radiation of the group. Here, we describe Winneshiekia youngae gen. et sp. nov., a euchelicerate from the Middle Ordovician (Darriwilian) Winneshiek Lagerstätte of Iowa, USA. Winneshiekia shares features with both xiphosurans (a large, semicircular carapace and ophthalmic ridges) and dekatriatan euchelicerates such as chasmataspidids and eurypterids (an opisthosoma of 13 tergites). Phylogenetic analysis resolves Winneshiekia at the base of Dekatriata, as sister taxon to a clade comprising chasmataspidids, eurypterids, arachnids, and Houia. Winneshiekia provides further support for the polyphyly of synziphosurines, traditionally considered the stem lineage to xiphosurid horseshoe crabs, and by extension the paraphyly of Xiphosura. The new taxon reveals the ground pattern of Dekatriata and provides evidence of character polarity in chasmataspidids and eurypterids. The Winneshiek Lagerstätte thus represents an important palaeontological window into early chelicerate evolution.

  5. 75 FR 3468 - Revised Jurisdictional Thresholds For Section 7A of the Clayton Act (United States)


    ... amendment of Section 7A of the Clayton Act. Section 7A of the Clayton Act, 15 U.S.C. 18a, as added by the... FEDERAL TRADE COMMISSION Revised Jurisdictional Thresholds For Section 7A of the Clayton Act... U.S.C. Sec. 7A. By direction of the Commission. Donald S. Clark, Secretary. [FR Doc. 2010-1039 Filed...

  6. 76 FR 4349 - Revised Jurisdictional Thresholds for Section 7a of The Clayton Act (United States)


    ... amendment of Section 7A of the Clayton Act. Section 7A of the Clayton Act, 15 U.S.C. 18a, as added by the... FEDERAL TRADE COMMISSION Revised Jurisdictional Thresholds for Section 7a of The Clayton Act... Notification Office, (202) 326-3100. Authority: 16 U.S.C. 7A. By direction of the Commission. Donald S. Clark...

  7. 12 CFR 212.9 - Effect of Interlocks Act on Clayton Act. (United States)


    ... MANAGEMENT OFFICIAL INTERLOCKS § 212.9 Effect of Interlocks Act on Clayton Act. The Board regards the provisions of the first three paragraphs of section 8 of the Clayton Act (15 U.S.C. 19) to have been... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Effect of Interlocks Act on Clayton Act. 212.9...

  8. Harold Clayton Urey: 29 April 1893 - 5 January 1981

    International Nuclear Information System (INIS)

    Cohen, K.P.; Runcorn, S.K.; Suess, H.E.; Thode, H.G.


    The career of Harold Clayton Urey is described in detail in three parts: (i) prewar career 1893-1940 and the award of the Nobel prize in chemistry, (ii) war years 1939-44 and the atomic bomb, (iii) post-war career 1945-81 and the solar system. His research work in atomic physics, lunar physics and astronomy is outlined. (U.K.)

  9. 75 FR 3469 - Revised Jurisdictional Thresholds For Section 8 of the Clayton Act (United States)


    ... FEDERAL TRADE COMMISSION Revised Jurisdictional Thresholds For Section 8 of the Clayton Act AGENCY... thresholds for interlocking directorates required by the 1990 amendment of Section 8 of the Clayton Act..., (202) 326-2879. Authority: 15 U.S.C. Sec. 19(a)(5)). By direction of the Commission. Donald S. Clark...

  10. 76 FR 4349 - Revised Jurisdictional Thresholds for Section 8 of the Clayton Act (United States)


    ... FEDERAL TRADE COMMISSION Revised Jurisdictional Thresholds for Section 8 of the Clayton Act AGENCY... thresholds for interlocking directorates required by the 1990 amendment of Section 8 of the Clayton Act..., (202) 326-2879. Authority: 15 U.S.C. 19(a)(5). By direction of the Commission. Donald S. Clark...

  11. 78 FR 29611 - Prevailing Rate Systems; Redefinition of the Clayton-Cobb-Fulton, Georgia, Nonappropriated Fund... (United States)


    ... Clayton-Cobb-Fulton, Georgia, Nonappropriated Fund Federal Wage System Wage Area AGENCY: U.S. Office of... Clayton County without NAF employment. Under 5 U.S.C. 5343(a)(1)(B)(i), NAF wage areas ``shall not extend... 44 U.S.C. 1510. #0; #0;The Code of Federal Regulations is sold by the Superintendent of Documents. #0...

  12. New aging properties of the Clayton-Oakes model based on multivariate dispersion


    Arias-Nicolás, José Pablo


    In this work we present a recent definition of Multivariate Increasing Failure Rate (MIFR) based on the concept of multivariate dispersion. This new definition is an extension of the univariate characterization of IFR distributions under dispersive ordering of the residual lifetimes. We apply this definition to the Clayton-Oakes model. In particular, we provide several conditions to order in the multivariate dispersion sense the residual lifetimes of random vectors with a dependence structure...

  13. Streamflow and water-quality data for Meadow Run Basin, Fayette County, Pennsylvania, December 1987-November 1988. Open file report

    International Nuclear Information System (INIS)

    Kostelnik, K.M.; Witt, E.C.


    Streamflow and water-quality data were collected throughout the Meadow Run basin, Fayette County, Pennsylvania, from December 7, 1987 through November 15, 1988, to determine the prevailing quality of surface water over a range of hydrologic conditions. The data will assist the Pennsylvania Department of Environmental Resources during its review of coal-mine permit applications. A water-quality station near the mouth of Meadow Run provided continuous-record of stream stage, pH, specific conductance, and water temperature. Monthly water-quality samples collected at the station were analyzed for total and dissolved metals, nutrients, major cations and anions, and suspended-sediment concentrations

  14. Origin and Evolution of Li-rich Brines at Clayton Valley, Nevada, USA (United States)

    Munk, L. A.; Bradley, D. C.; Hynek, S. A.; Chamberlain, C. P.


    Lithium is the key component in Li-ion batteries which are the primary energy storage for electric/hybrid cars and most electronics. Lithium is also an element of major importance on a global scale because of interest in increasing reliance on alternative energy sources. Lithium brines and pegmatites are the primary and secondary sources, respectively of all produced Li. The only Li-brine in the USA that is currently in production exists in Clayton Valley, NV. The groundwater brines at Clayton Valley are located in a closed basin with an average evaporation rate of 142 cm/yr. The brines are pumped from six aquifer units that are composed of varying amounts of volcanic ash, gravel, salt, tufa, and fine-grained sediments. Samples collected include spring water, fresh groundwater, groundwater brine, and meteoric water (snow). The brines are classified as Na-Cl waters and the springs and fresh groundwater have a mixed composition and are more dilute than the brines. The Li content of the waters in Clayton Valley ranges from less than 1 μg/L (snow) up to 406.9 mg/L in the lower ash aquifer system (one of six aquifers in the basin). The cold springs surrounding Clayton Valley have Li concentrations of about 1 mg/L. A hot spring located just east of Clayton Valley contains 1.6 mg/L Li. The Li concentration of the fresh groundwater is less than 1 mg/L. Hot groundwater collected in the basin contain 30-40 mg/L Li. Water collected from a geothermal drilling north of Silver Peak, NV, had water with 4.9 mg/L Li at a depth of >1000m. The δD and δ18O isotopic signatures of fresh groundwater and brine form an evaporation path that extends from the global meteoric water line toward the brine from the salt aquifer system (the most isotopically enriched brine with ave. δD = -3.5, ave. δ18O = -67.0). This suggests that mixing of inflow water with the salt aquifer brine could have played an important role in the evolution of the brines. Along with mixing, evaporation appears to

  15. Messages for Educational Leadership: The Constance E. Clayton Lectures 1998-2007. Black Studies and Critical Thinking. Volume 34 (United States)

    Slaughter-Defoe, Diana T., Ed.


    Urban education is an interdisciplinary field, characterized by introducing many perspectives to research pertaining to educational policy and to the practice of educating youth whose lives unfold in densely populated urban metropolitan areas. This book celebrates Constance Clayton's eleven-year tenure as superintendent of the School District of…

  16. 76 FR 62330 - Radio Broadcasting Services; Alamo, GA; Alton, MO; Boscobel, WI; Buffalo, OK; Cove, AR; Clayton... (United States)


    ... Broadcasting Services; Alamo, GA; Alton, MO; Boscobel, WI; Buffalo, OK; Cove, AR; Clayton, LA; Daisy, AR; Ennis...) 418-2180. SUPPLEMENTARY INFORMATION: This is a synopsis of the Commission's Notice of Proposed Rule... FCC's Reference Information Center at Portals II, CY-A257, 445 Twelfth Street, SW., Washington, DC...

  17. LGBT health and vaccinations: Findings from a community health survey of Lexington-Fayette County, Kentucky, USA. (United States)

    Jones, Jeff; Poole, Asheley; Lasley-Bibbs, Vivian; Johnson, Mark


    Data on adult immunization coverage at the state level and for LGBT Americans in particular are sparse. This study reports the results of a 2012 Lexington-Fayette County, Kentucky, community health assessment's results asking about eight adult vaccinations among 218 lesbian, gay, bisexual, and transgendered (LGBT) respondents. Researchers collected data using an online survey distributed through LGBT social media, posters, and LGBT print media. The LGBT sample largely matches the demographics of the county as a whole except this group reports higher level of education and fewer uninsured individuals. Among LGBT respondents, immunization prevalence reaches 68.0% (annual Influenza), 65.7% (Hepatitis B), 58.8% (Chickenpox/Varicella), 55.9% (Hepatitis A), 41.2% (Smallpox), and 25.8% (Pneumonia). Among respondents who are currently within the recommended 19-26 years age range for the Human Papillomavirus (HPV) vaccine, the LGBT females are less likely to report receiving the vaccine (15.4%) compared to the national coverage percentage of 34.5%. Males, however, are more likely to have received the vaccine (10.3%) than the national percentage of 2.3%. The small number of LGBT seniors in the study report a much higher prevalence of the Shingles (Herpes Zoster) vaccines than for U.S. seniors 60 and older (71.4% compared to 20.1% nationally). LGBT respondents report higher percentages of adult vaccination. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Evaluating Hydrologic Transience in Watershed Delineation, Numerical Modeling and Solute Transport in the Great Basin. Clayton Valley, Nevada (United States)

    Underdown, C. G.; Boutt, D. F.; Hynek, S. A.; Munk, L. A.


    Importance of transience in managed groundwater systems is generally determined by timeframe of management decisions. Watersheds with management times shorter than the aquifer (watershed) response time, or the time it takes a watershed to recover from a change in hydrologic state, would not include the new state and are treated as steady-state. However, these watersheds will experience transient response between hydrologic states. Watershed response time is a function of length. Therefore flat, regional watersheds characteristic of the Great Basin have long response times. Defining watershed extents as the area in which the water budget is balanced means inputs equal outputs. Steady-state budgets in the Great Basin have been balanced by extending watershed boundaries to include more area for recharge; however, the length and age of requisite flow paths are poorly constrained and often unrealistic. Inclusion of stored water in hydrologic budget calculations permits water balance within smaller contributing areas. As groundwater flow path lengths, depths, and locations differ between steady-state and transient systems, so do solute transport mechanisms. To observe how transience affects response time and solute transport, a refined (transient) version of the USGS steady-state groundwater flow model of the Great Basin is evaluated. This model is used to assess transient changes in contributing area for Clayton Valley, a lithium-brine producing endorheic basin in southwestern Nevada. Model runs of various recharge, discharge and storage bounds are created from conceptual models based upon historical climate data. Comparing results of the refined model to USGS groundwater observations allows for model validation and comparison against the USGS steady-state model. The transient contributing area to Clayton Valley is 85% smaller than that calculated from the steady-state solution, however several long flow paths important to both water and solute budgets at Clayton Valley

  19. Disruptive innovation: can health care learn from other industries? A conversation with Clayton M. Christensen. Interview by Mark D. Smith. (United States)

    Christensen, Clayton M


    Clayton Christensen is one of America's most influential business thinkers and writers. A professor at Harvard Business School, Christensen is perhaps best known for his writings on disruptive innovation in such books as The Innovator's Dilemma and The Innovator's Solution. In this interview with the California HealthCare Foundation's Mark Smith, he argues that the answer for more affordable health care will come not from an injection of more funding but, rather, from innovations that aim to make more and more areas of care cheaper, simpler, and more in the hands of patients. Christensen has been an adviser to several new companies in health care.

  20. Dewatering of the Clayton Formation during construction of the Walter F George Lock and Dam, Fort Gaines, Clay County, Georgia (United States)

    Stewart, J.W.


    Walter F. George Lock and Dam, the largest manmade structure in the South, extends over 2llz miles across the flood plain of the Chattahoochee River at Fort Gaines, Clay County, in southwest Georgia and in Henry County, in southeast Alabama. The multipurpose dam consists of two rolled-filled earth dikes, a concrete spillway, a single-stage lock with an 88-foot lift, and a 130,000 kilowatt capacity powerhouse. The foundation of the dam at the river is constructed in the Clayton Formation, and the earth dikes are constructed on river terraces at about 150 feet above msl (mean sea level). At the damsite, the top of the Clayton Formation consists of an "earthy" limestone, which is about 35 feet thick except in the river channel, where it is 12 to 15 feet thick; a "shell" limestone, which averages about 40 feet thick; and a basal "sandy" limestone, which averages about 35 feet thick. The Providence Sand underlies the "sandy" limestone and its thickness is about 175 feet at the damsite. These formations contain water under artesian conditions. The "shell" unit of the Clayton was the principal water-bearing formation pumped during construction of the lock and dam. The large yields of the wells from concentrated areas over extended periods of time indicate that in the vicinity of the Chattahoochee River, the Clayton Formation is a productive aquifer with transmissivity ranging from 48,000 to 77,000 gpd per ft. (gallons per day per foot) and storage coefficient ranging from 2.5 x 10?3 to 2.8 x 10?5. At the spillway site, pumpage ranged from an average of 1,700 to 8,400 gpm (gallons per minute) during the period April 1957 to July 1959; at the powerhouse site, pumpage ranged from 1,600 to 5,000 gpm during the period October 1957 to September 1961; and at the lock site, pumpage ranged from 4,000 to 5,000 gpm during the period July 1960 through December 1961. The large yields represent a source of large quantities of ground water available for industrial and other uses in an

  1. Public health assessment for petitioned public health assessment, Shaffer Equipment Company, Minden, Fayette County, West Virginia, Region 3. CERCLIS No. WVD981038300. Final report

    International Nuclear Information System (INIS)


    The Shaffer Equipment Company (SEC) site, located in Fayette County, Minden, West Virginia constructed electrical substations for area coal mines from the period 1970 to 1984. The site is approximately one acre and has one building (SEC Equipment Building) that served as both a warehouse and office. Electrical equipment such as transformers, switches, circuit breakers, and capacitors were stored on the site. Dielectric oils that contained polychlorinated biphenyls (PCBs) and 1,2,4-trichlorobenzene were found in on- and off-site soils and sediments. Because PCBs are on site and PCB-contaminated oils reportedly were burned as starter fuel in the warehouse/office building, on- and off-site soil samples and on-site sediment samples were analyzed for polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzo-p-furans (PCDFs). One present potential pathway of exposure that has been identified as past, present, and future concerns involve trespassers onto the SEC site, children playing in yards and Arbuckle Creek, on-site workers in the SEC Equipment Building, and persons that eat snapping turtles from the area

  2. 78 FR 51203 - Iowa; Major Disaster and Related Determinations (United States)


    ... and Emergency Assistance Act, 42 U.S.C. 5121 et seq. (the ``Stafford Act''), as follows: I have... disaster declaration under the Robert T. Stafford Disaster Relief and Emergency Assistance Act, 42 U.S.C...: Allamakee, Benton, Buchanan, Butler, Cedar, Clayton, Delaware, Howard, Jones, and Winneshiek Counties for...


    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...


    Federal Emergency Management Agency, Department of Homeland Security — Terrain data, as defined in FEMA Guidelines and Specifications, Appendix M: Data Capture Standards, describes the digital topographic data that was used to create...

  5. FLOODPLAIN MAPPING, Fayette COUNTY, IN (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  6. Geochemical characterization of slags, other mines wastes, and their leachates from the Elizabeth and Ely mines (Vermont), the Ducktown mining district (Tennessee), and the Clayton smelter site (Idaho) (United States)

    Piatak, Nadine M.; Seal, Robert R.; Hammarstrom, Jane M.; Meier, Allen L.; Briggs, Paul H.


    Waste-rock material produced at historic metal mines contains elevated concentrations of potentially toxic trace elements. Two types of mine waste were examined in this study: sintered waste rock and slag. The samples were collected from the Elizabeth and Ely mines in the Vermont copper belt (Besshi-type massive sulfide deposits), from the Copper Basin mining district near Ducktown, Tennessee (Besshi-type massive sulfide deposits), and from the Clayton silver mine in the Bayhorse mining district, Idaho (polymetallic vein and replacement deposits). The data in this report are presented as a compilation with minimal interpretation or discussion. A detailed discussion and interpretation of the slag data are presented in a companion paper. Data collected from sintered waste rock and slag include: (1) bulk rock chemistry, (2) mineralogy, (3) and the distribution of trace elements among phases for the slag samples. In addition, the reactivity of the waste material under surficial conditions was assessed by examining secondary minerals formed on slag and by laboratory leaching tests using deionized water and a synthetic solution approximating precipitation in the eastern United States.

  7. 78 FR 45549 - Iowa; Major Disaster and Related Determinations (United States)


    ... and Emergency Assistance Act, 42 U.S.C. 5121 et seq. (the ``Stafford Act''), as follows: I have... U.S.C. 5121 et seq. (the ``Stafford Act''). Therefore, I declare that such a major disaster exists..., Clay, Clayton, Crawford, Davis, Delaware, Des Moines, Fayette, Floyd, Franklin, Greene, Grundy, Hardin...

  8. Clayton 1:100000 Quad Transportation DLGs (United States)

    Earth Data Analysis Center, University of New Mexico — Digital line graph (DLG) data are digital representations of cartographic information. DLG's of map features are converted to digital form from maps and related...

  9. Clayton 1:100000 Quad Hydrography DLGs (United States)

    Earth Data Analysis Center, University of New Mexico — Digital line graph (DLG) data are digital representations of cartographic information. DLG's of map features are converted to digital form from maps and related...

  10. Archaeological Investigations at Clayton Lake, Southeast Oklahoma. Phase II. (United States)


    absolute dating from the excavations will be of utmost concern. These include the collection of radiocarbon and archaeomagnetic samples whenever...modify the nature and number of occupations at the site. 4. To obtain materials for absolute dating , both radiocarbon and archaeomagnetic , in order to...structures were recorded and partially exposed. Ten radiocarbon dates and three archaeomagnetic dates were obtained, but several inconsistencies occurred

  11. 78 FR 2406 - Revised Jurisdictional Thresholds of the Clayton Act (United States)


    ... those thresholds annually, based on the change in gross national product, in accordance with Section 8(a... similarly indexed and, as a result, have not been adjusted for inflation in over a decade. The new...


    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...


    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...


    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  15. TIGER/Line Shapefile, 2013, county, Fayette County, OH, Current Address Ranges Relationship File (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  16. Microsporogenesis in Brachiaria bovonei (Chiov. Robyns and B. subulifolia (Mez Clayton (Poaceae Microsporogênese em Brachiaria bovonei (Chiov. Robyns e B. subulifolia (Mez Clayton (Poaceae

    Directory of Open Access Journals (Sweden)

    Claudicéia Risso-Pascotto


    Full Text Available Some African species of Brachiaria have been introduced into the Americas and became the most important forage for pastures in the tropics. New cultivars can be obtained either from direct selections from the natural existing variability in the germplasm collections or from interspecific hybridizations. Polyploidy is predominant in the genus Brachiaria and correlated with apomixis which complicates hybridization. The objective of cytological studies underway on the Brachiaria germplasm collection at Embrapa Beef Cattle is to determine the chromosome number and meiotic behavior of accessions. For the breeding of Brachiaria species, compatible sexual and apomictic accessions need to be identified. Microsporogenesis was evaluated in two accessions of Brachiaria bovonei (BO01 and BO05 and one accession of B. subulifolia (SU01. BO01 is pentaploid (2n = 5x = 45, BO05 is tetraploid (2n = 4x = 36, and SU01 is hexaploid (2n = 6x = 54, derived from x = 9. Meiotic abnormalities typical of polyploids, characterized by precocious chromosome migration to the poles in metaphases, laggard chromosomes in anaphases, and micronuclei in telophases and tetrads, were recorded in high frequency in all the accessions generating unbalanced gametes. Both accessions of B. bovonei presented chromosome stickiness. The results are discussed in the view of the Brachiaria breeding program objectives.Algumas espécies africanas de Brachiaria foram introduzidas nas Américas e tornaram-se importantes pastagens nos trópicos. Novas cultivares podem ser obtidas por seleção direta da variabilidade genética existente na coleção de germoplasma ou por hibridização interespecífica. Poliploidia é predominante no gênero Brachiaria e correlacionada com apomixia, o que complica a hibridização. O objetivo dos estudos citogenéticos na coleção de germoplasma de Brachiaria da Embrapa Gado de Corte é determinar o número de cromossomos e o comportamento meiótico dos acessos. A microsporogênese foi avaliada em dois acessos de Brachiaria bovonei (BO01 e BO05 e um acesso de B. subulifolia (SU01. BO01 é pentaplóide (2n = 5x = 45, BO05 é tetraplóide (2n = 4x = 36, e SU01 é hexaplóide (2n = 6x = 54, todos derivados de x = 9. Anormalidades meióticas típicas de poliplóides, caracterizadas por migração precoce de cromossomos para os pólos em metáfases, cromossomos retardatários em anáfases, e micronúcleos em telófases e tétrades foram observadas em alta freqüência em todos os acessos gerando gametas geneticamente desbalanceados. Ambos os acessos de B. bovonei apresentaram aderências cromossômicas. Os resultados são discutidos sob o ponto de vista dos objetivos do melhoramento genético.

  17. 77 FR 4323 - Revised Jurisdictional Thresholds for Section 7A of the Clayton Act (United States)


    ... those thresholds annually, based on the change in gross national product, in accordance with Section 8(a... similarly indexed and, as a result, have not been adjusted for inflation in over a decade. The new...

  18. 78 FR 60181 - Prevailing Rate Systems; Redefinition of the Clayton-Cobb-Fulton, Georgia, Nonappropriated Fund... (United States)


    ... OFFICE OF PERSONNEL MANAGEMENT 5 CFR Part 532 RIN 3206-AM84 Prevailing Rate Systems; Redefinition.... Office of Personnel Management. ACTION: Final rule. SUMMARY: The U.S. Office of Personnel Management (OPM..., from the wage area definition. The name of the wage area will be Cobb, GA. These changes are necessary...

  19. The Prehistory of the Proposed Clayton Lake Area, Southeast Oklahoma. Phase I Investigations. (United States)


    Other (drills, wedges, tested cobbles, bifaces, preforms, cores, etc.) .2 Biface fragment .3 Uniface ( unifaces , modified flakes, modified blocky...10 Historic material IV. Artifact number (given to all categories except unifaces ). V. Count only: Flakes (including blocky debris). ’ • i m mimt

  20. Geography and Higher Education in the 1980s: An Interview with Keith Clayton. (United States)

    Lee, Roger; Gray, Murray


    Presents a senior British academic's perspectives on geography's major concerns, priorities, and objectives. Topics include: geography as a discipline; structure and divisions of academic labor; teaching versus research; and future transformations. (TRS)

  1. 78 FR 67215 - Norfolk Southern Railway Company-Abandonment Exemption-in Fayette and Wayne Counties, Ind.; C&NC... (United States)


    ... agencies) have been met. As a condition to these exemptions, any employee adversely affected by the... whether this condition adequately protects affected employees, a petition for partial revocation under 49... environment and historic resources. OEA will issue an environmental assessment (EA) by November 15, 2013...

  2. Blade design and operating experience on the MOD-OA 200 kW wind turbine at Clayton, New Mexico (United States)

    Linscott, B. S.; Shaltens, R. K.


    Two 60 foot long aluminum wind turbine blades were operated for over 3000 hours on the MOD-OA wind turbine. The first signs of blade structural damage were observed after 400 hours of operation. Details of the blade design, loads, cost, structural damage, and repair are discussed.

  3. Stratigraphic Framework and Depositional Sequences in the Lower Silurian Regional Oil and Gas Accumulation, Appalachian Basin: From Licking County, Ohio, to Fayette County, West Virginia (United States)

    Ryder, Robert T.


    The Lower Silurian regional oil and gas accumulation was named by Ryder and Zagorski (2003) for a 400-mile (mi)-long by 200-mi-wide hydrocarbon accumulation in the central Appalachian basin of the Eastern United States and Ontario, Canada. From the early 1880s to 2000, approximately 300 to 400 million barrels of oil and eight to nine trillion cubic feet of gas have been produced from the Lower Silurian regional oil and gas accumulation (Miller, 1975; McCormac and others, 1996; Harper and others, 1999). Dominant reservoirs in the regional accumulation are the Lower Silurian 'Clinton' and Medina sandstones in Ohio and westernmost West Virginia and coeval rocks in the Lower Silurian Medina Group (Grimsby Sandstone (Formation) and Whirlpool Sandstone) in northwestern Pennsylvania and western New York. A secondary reservoir is the Upper Ordovician(?) and Lower Silurian Tuscarora Sandstone in central Pennsylvania and central West Virginia, a more proximal eastern facies of the 'Clinton' sandstone and Medina Group (Yeakel, 1962; Cotter, 1982, 1983; Castle, 1998). The Lower Silurian regional oil and gas accumulation is subdivided by Ryder and Zagorski (2003) into the following three parts: (1) an easternmost part consisting of local gas-bearing sandstone units in the Tuscarora Sandstone that is included with the basin-center accumulation; (2) an eastern part consisting predominantly of gas-bearing 'Clinton' sandstone-Medina Group sandstones that have many characteristics of a basin-center accumulation (Davis, 1984; Zagorski, 1988, 1991; Law and Spencer, 1993); and (3) a western part consisting of oil- and gas-bearing 'Clinton' sandstone-Medina Group sandstones that is a conventional accumulation with hybrid features of a basin-center accumulation (Zagorski, 1999). With the notable exception of the offshore part of Lake Erie (de Witt, 1993), the supply of oil and (or) gas in the hybrid-conventional part of the regional accumulation continues to decline because of the many wells drilled there since the late 1880s. However, new gas and local oil continues to be discovered in the deeper basin-center part (Zagorski, 1991; Pees, 1994; Petroleum Information Corporation, 1994). In general, only small quantities of gas have been produced from the Tuscarora Sandstone fields because of their generally poor reservoir quality and because of the low energy (Btu) content of the gas (Avary, 1996). Although fracture porosity is the dominant porosity type in the Tuscarora Sandstone gas reservoirs (Avary, 1996), there are several fields, such as Indian Creek, where intergranular porosity seems to be important (Bruner, 1983; Castle and Byrnes, 2005). In order to better understand the character and origin of the Lower Silurian regional oil and gas accumulation and its component parts, six cross sections were drawn through the Lower Silurian strata in parts of New York, Ohio, Pennsylvania, and West Virginia. The locations of all six cross sections are shown on sheet 2 (figs. 1 and 2) of this report. Each cross section shows the stratigraphic framework, depositional setting, sequence stratigraphy, and hydrocarbon-producing intervals of the Lower Silurian sandstone reservoirs and adjoining strata. Cross section F-F' presented here is about 215 mi long and trends northwestward, approximately normal to the depositional strike of the Lower Silurian sandstone system, and extends through large stretches of the basin-center and hybrid-conventional parts of the Lower Silurian regional oil and gas accumulation.

  4. 78 FR 72914 - Changes in Flood Hazard Determinations (United States)


    ..., Department, 140 index.php/georgia/ 0476P). Fayette County Stonewall Avenue fayette-3/. Board of West, Suite 203, Commissioners, Fayetteville, GA 140 Stonewall 30214. Avenue West, Suite 100, Fayetteville, GA...

  5. Efecto de la profundidad del suelo en rottboellia cochinchinensis (lour clayton en caña de azúcar (saccharum officinarum l.

    Directory of Open Access Journals (Sweden)

    Ram\\u00F3n Le\\u00F3n


    Full Text Available Se muestrearon cuatro lotes con diferente textura de suelo, sembrados con caña de azúcar durante cuatro años consecutivos. El lote A con suelo franco arcilloso, el lote B con suelo franco arenoso, el lote C con suelo arcilloso y el lote D con suelo franco. Se seleccionaron lotes con una población de R. cochinchinensis de 75 a 150 plantas/ m2. Se contó el número de plantas de la maleza en un área de 0,25 m2, en dos micro-hábitats: el surco y entre-surco. A cada planta se le escarbó el suelo que la rodeaba hasta encontrar la semilla de la que provenía y se midió la profundidad a la que ésta se encontró, para luego determinar qué porcentaje del total de plantas contabilizadas provenía de semillas localizadas en cada uno de los siguientes estratos: 0,0; >0,0 a 2,5; >2,5 a 5,0; >5,0 a 10 y >10,0 a 15,0 cm de profundidad. Además, se evaluó en invernadero el efecto de cada profundidad de los estratos citados. A nivel de laboratorio y en platos Petri, se evaluó el efecto de la luz y la oscuridad sobre la germinación de la semilla de R. cochinchinensis. Se encontró que la mayoría de las plantas en campo provenían de semillas que se encontraban de >0 a 2,5 cm, seguido por aquellas que estaban de >2,5 a 5,0 cm donde se dieron las mejores condiciones para la germinación. No se observaron diferencias entre los tipos de suelo o los micro-hábitats evaluados. En invernadero el tratamiento a 0,0 cm fue el que mostró la mayor germinación y esto fue producto de la exposición a la luz, lo cual se corroboró en el estudio en laboratorio donde el tratamiento con luz presentó también, la mayor germinación

  6. National Dam Inspection Program. Colonial Dam Number 3, (NDI Number PA-00209, PennDER Number 26-22) Ohio River Basin, Fayette County, Pennsylvania. Phase I Inspection Report. (United States)


    water supply purposes and its current use is unknown. g. Design and Construction History : The dam was designed in 1907 by E. J.Taylor, Chief Engineer and...the ratio of resistire to overtmrniLt aete. ad@o the tactor of ar𔄀- posesa by tOn bectla a6%1=+. roation aheu.. Ito tas. Ux 1~ abomw the ratio ar

  7. Building America Case Study: Heat Pump Water Heater Ducting Strategies with Encapsulated Attics in Climate Zones 2 and 4, LaFayette, Georgia (CZ4), and Savannah, Georgia (CZ2)

    Energy Technology Data Exchange (ETDEWEB)

    V. Kochkin, M. Sweet


    The focus of this study is on the performance of HPWHs with several different duct configurations and their effects on whole building heating, cooling, and moisture loads. A.O. Smith 60 gallon Voltex (PHPT-60) heat pump water heaters (HPWHs) were included at two project sites and ducted to or located within spray foamed encapsulated attics. The effect of ducting a HPWH's air stream does not diminish its efficiency if the ducting does not reduce intake air temperature, which expands HPWH application to confined areas. Exhaust ducts should be insulated to avoid condensation on the exterior, however this imposes a risk of condensation occurring in the duct's interior near the HPWH due to large variation of temperatures between the compressor and the duct and the presence of bulk moisture around the condenser. The HPWH's air conditioning impact on HVAC equipment loads is minimal when the intake and exhaust air streams are connected to a sealed attic and not the living space. A HPWH is not suitable as a replacement dehumidifier in sealed attics as peak moisture loads were observed to only be reduced if the heat pump operated during the morning. It appears that the intake air temperature and humidity was the most dominant variable affecting HPWH performance. Different ducting strategies such as exhaust duct only, intake duct only, and exhaust and intake ducting did not have any effect on HPWH performance.

  8. National Dam Inspection Program. Star Junction Number 1 Dam (NDI Number PA-00198, PennDER Number 26-30) Ohio River Basin, Washington Run, Fayette County, Pennsylvania. Phase I Inspection Report, (United States)


    end and erosion K of the training dike has occurred. g. Instrumentation : No instrumentation was observed during the inspection. h. Downstream...DATE: 19 MAR 80 RN TDZ: 10.30.40 NATIONAL PROGR FOR TEM INSPEC ION OF NON-FEERAL DM HXDROLOMC AND MRAILIC ANALISIS OF STAR JUNCTION NamR 1 DAm PROBABLE

  9. 77 FR 68073 - Prevailing Rate Systems; Redefinition of the St. Louis, MO; Southern Missouri; Cleveland, OH; and... (United States)


    ... Shannon Stoddard Stone Taney Texas Vernon Wayne Wright * * * * * NEW MEXICO Albuquerque Survey Area New... Allegheny National Forest portion) Erie Fayette Forest (Does not include the Allegheny National Forest...

  10. Comments on Clayton M. Darwin and Loretta S. Gray's "Going after the Phrasal Verb: An Alternative Approach to Classification" [and] A Reader Reacts [and] Another Reader Reacts [and] The Authors Respond. (United States)

    Sawyer, Joan H.; Sheen, Ron; Darwin, Clayton M.; Gray, Loretta S.


    Raises questions regarding the classification system Darwin and Gray offer for phrasal verbs on the basis of utility in the classroom. Darwin and Gray clarify the purpose of their classification system and provide additional corpus-based data. (Author/VWL)

  11. 40 CFR 81.311 - Georgia. (United States)


    ... AREAS FOR AIR QUALITY PLANNING PURPOSES Section 107 Attainment Status Designations § 81.311 Georgia... X Evans County X Fannin County X Fayette County X Floyd County X Forsyth County X Franklin County X... X Evans County X Fannin County X Fayette County X Floyd County X Forsyth County X Franklin County X...

  12. Genetics Home Reference: blepharophimosis, ptosis, and epicanthus inversus syndrome (United States)

    ... Meire F, Oyen N, Wilson LC, Barel D, Clayton-Smith J, de Ravel T, Decock C, Delbeke ... Raes J, Leroy BP, Lucassen A, Yates JR, Clayton-Smith J, Ilyina H, Brooks SS, Christin-Maitre S, Fellous ...

  13. Vasopressin in perioperative management of congenital ...

    African Journals Online (AJOL)

    vascular resistance and improvement in cardiac output and reduced need for inotropes. This paradoxical response. (vasodilation in some vascular beds) distinguishes it from other vasoconstrictor agents. ... FRACP, Department of Paediatrics, Monash. University, 246, Clayton Road, Clayton, Melbourne, VIC 3168, Australia.

  14. Looking the other way Are Western scrub-Jays sensitive to the direction of attention of a conspecific simulated by video playback?


    Brecht, Katharina; Legg, Edward; Ostojic, Ljerka; Clayton, Nicola


    When observed by a conspecific, food-caching Western scrub-jays employ a number of different strategies to protect their caches from theft, for example by caching in visually inaccessible locations or re-caching more of those items that the observer could see being cached (Dally, Emery, & Clayton, 2004, 2005; Emery & Clayton, 2001). These findings suggest higher social cognitive abilities in these animals (Clayton, Dally, & Emery, 2007; Clayton, 2014). The present study aimed to determine whe...

  15. Parental Education and Public Reason: Why Comprehensive Enrolment Is Justified (United States)

    Giesinger, Johannes


    Matthew Clayton claims that "comprehensive enrolment"--raising one's children in accordance with one's own conception of the good--is illegitimate. In his argument against comprehensive enrolment, Clayton refers to Rawls's idea of public reason. In a recent response to Clayton, Christina Cameron not only rejects…

  16. 78 FR 21515 - Prevailing Rate Systems; Redefinition of the St. Louis, MO; Southern Missouri; Cleveland, OH; and... (United States)


    ... Scott Shannon Stoddard Stone Taney Texas Vernon Wayne Wright * * * * * NEW MEXICO Albuquerque Survey... include the Allegheny National Forest portion) Erie Fayette Forest (Does not include the Allegheny National Forest portion) Greene Huntingdon Indiana Jefferson Lawrence Potter Somerset Venango West Virginia...

  17. Fiberglass reinforced polymer composite bridge deck construction in Illinois (United States)


    An experiment was conducted using a fiber reinforced polymer composite material for the bridge deck of a low volume bridge. The test location was on South Fayette Street over the Town Brook in Jacksonville, Illinois. This project included removal of ...

  18. Commentary on: Christensen, Clayton M. : Disruptive Innovation. In: Soegaard, Mads and Dam, Rikke Friis (eds.). "Encyclopedia of Human-Computer Interaction". Aarhus, Denmark: The Foundation. Available online at

    NARCIS (Netherlands)

    Steen, M.G.D.


    Book : A disruptive technology or disruptive innovation is an innovation that helps create a new market and value network, and eventually goes on to disrupt an existing market and value network. The term is used in business and technology literature to describe innovations that improve a product or

  19. Weapons: A Report on the Industry

    National Research Council Canada - National Science Library

    Maybaumwisniewski, Susan; Brown, Shannon; Kreitler, Walter


    .... This paper examines the industry's ability to perceive and effectively incorporate disruptive innovations, as defined by Clayton Christensen, which may dramatically change the nature of the industry...

  20. What Can What-When-Where (WWW) Binding Tasks Tell Us about Young Children's Episodic Foresight? Theory and Two Experiments (United States)

    Russell, James; Cheke, Lucy G.; Clayton, Nicola S.; Meltzoff, Andrew N.


    We analyze theoretical differences between conceptualist and minimalist approaches to episodic processing in young children. The "episodic-like" minimalism of Clayton and Dickinson (1998) is a species of the latter. We asked whether an "episodic-like" task (structurally similar to ones used by Clayton and Dickinson) in which participants had to…

  1. 27 CFR 9.46 - Livermore Valley. (United States)


    ...) Clayton, CA (1953; Photorevised 1980; Minor Revision 1994); (2) Diablo, Calif. (1953; Photorevised 1980... Livermore Valley viticultural area's boundary is defined as follows: (1) The beginning point is on the Clayton map at the peak of Mount Diablo (VABM 3849) where the Mount Diablo Base Line and Mount Diablo...

  2. Genetics Home Reference: riboflavin transporter deficiency neuronopathy (United States)

    ... K, McGarvey ML, Scherer SS, Baxter PS, King MD, Clayton P, Rahman S, Reilly MM, Ouvrier RA, Christodoulou J, ... Foley AR, Arepalli S, Pandraud A, Simón-Sánchez J, Clayton P, Reilly MM, Muntoni F, Abramzon Y, Houlden ...

  3. 16 CFR 2.41 - Reports of compliance. (United States)


    ... provisions of section 5(l) of the Federal Trade Commission Act (15 U.S.C. 45(l)) and section 11(1) of the Clayton Act, as amended (15 U.S.C. 21(1)), to enforce compliance with an order, without advising a... section 11 of the Clayton Act, as amended, and except as otherwise specifically provided in any such order...

  4. 40 CFR 81.316 - Iowa. (United States)


    ... Des Moines east of U.S. Highway 65 & 69 (E. 14th Street) X Portions of Polk County contained entirely... Cerro Gordo County Cherokee County Chickasaw County Clarke County Clay County Clayton County Clinton... Cerro Gordo County Cherokee County Chickasaw County Clarke County Clay County Clayton County Clinton...

  5. 75 FR 14577 - Proposed Collection; Comment Request (United States)


    ... whether the information shall have practical utility; (b) the accuracy of the agency's estimate of the.... Clayton Stokley, 8899 E. 56th Street, Indianapolis, IN 46249, or call Mr. Clayton Stokley at (317) 510... Department of Defense's (DoD) requirement for cashing personal checks overseas and on ship by DoD disbursing...

  6. Assessing the copula selection for bivariate frequency analysis ...

    Indian Academy of Sciences (India)


    upper tail copulas (Frank, Clayton and Gaussian), if there exists asymptotic dependence in the. 24 flood characteristics. ... characteristics and Frank, Clayton and Gaussian copulas are the appropriate copula models in. 30 ..... The mean of daily discharge of Trian stream gauge from 1978 to 2013 is 527.4 m3/s and the. 181.

  7. 78 FR 40545 - Notice of Final Federal Agency Action on Proposed Highway in Georgia the Interstate 75 (I-75... (United States)


    ... on Proposed Highway in Georgia the Interstate 75 (I-75) Express, Clayton and Henry Counties, Georgia... announces actions taken by FHWA and other Federal agencies that are final within the meaning of 23 U.S.C...) interchange in Clayton counties, a distance of approximately 17.94 miles. Those actions grant licenses...

  8. 77 FR 61606 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company (United States)


    ... of a family control group which consists of Clayton B. Patrick; Liz S. Patrick; Clayton M. Patrick... Holding Company The notificants listed below have applied under the Change in Bank Control Act (12 U.S.C. 1817(j)) and 225.41 of the Board's Regulation Y (12 CFR 225.41) to acquire shares of a bank or bank...

  9. 75 FR 65632 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification... (United States)


    ... Premerger Notification Rules Section 7A of the Clayton Act, 15 U.S.C. 18a, as added by Title II of the Hart... & Partners Fund II, L.P. G Air Medical Group Holdings, Inc. 21-SEP-10 20101071 G Finlav S.p.A. G Green... Charlesbank Equity Fund VII, Limited Partnership. G Blacksmith Brands Holdings, Inc. 20101156 G Clayton...

  10. 33 CFR 401.62 - Seaway stations. (United States)


    ...)—Iroquois Lock—Traffic Control Sector No. 3. WAG (Seaway Clayton)—Clayton, N.Y.—Traffic Control Sector No. 4... Long Point)—Port Colborne, Ontario—Traffic Control Sector No. 7. (68 Stat. 93-96, 33 U.S.C. 981-990, as...

  11. Genetics Home Reference: hypermanganesemia with dystonia (United States)

    ... or Free article on PubMed Central Tuschl K, Clayton PT, Gospe SM Jr, Gulab S, Ibrahim S, Singhi P, ... or Free article on PubMed Central Tuschl K, Clayton PT, Gospe SM Jr, Mills PB. Dystonia/Parkinsonism, ...

  12. 75 FR 49526 - Halliburton Company, Duncan Mfg., Including On-Site Leased Workers from Express Personnel... (United States)


    ... Company, Duncan Mfg., Including On-Site Leased Workers from Express Personnel, Clayton Personnel Service...''), 19 U.S.C. 2273, the Department of Labor issued a Certification of Eligibility to Apply for Worker...., including on-site leased workers from Express Personnel, Clayton Personnel Service and Manpower Planning...

  13. Mesoscale Modeling of Dynamic Compression of Boron Carbide Polycrystals (United States)


    occurs in ballistic impact, and accompanies amorphization in diamond anvil cell (DAC) experiments (Yan et al., 2009). Fracture in boron carbide ...Mesoscale Modeling of Dynamic Compression of Boron Carbide Polycrystals by J. D. Clayton ARL-RP-440 May 2013...Ground, MD 21005-5069 ARL-RP-440 May 2013 Mesoscale Modeling of Dynamic Compression of Boron Carbide Polycrystals J. D. Clayton

  14. 75 FR 29296 - Proposed Flood Elevation Determinations (United States)


    ... Tanana An area north of the Tanana +431 +432 Fairbanks-North Star River and Chena River. River levee and... of Old Airport Road and Mitchell Expressway to the west. An area north of the Tanana None +446 River...)....... Approximately 460 feet None +1004 Unincorporated Areas upstream of West Charles of Fayette County. Street. City...

  15. Aspects of the biology of Platorchestia fayetta sp. nov. (Crustacea ...

    African Journals Online (AJOL)

    Amphipods form an important component of coastal fauna and this study is focused on the biology of semi-terres- trial Platorchestia fayetta sp. nov. inhabiting sand and wave-cast algae on the north-eastern coast at Poste La Fayette, Mauritius. The population structure, size class variation, sex ratio and female reproductive ...

  16. 75 FR 29555 - Medicare Program; Medicare Coverage Gap Discount Program Model Manufacturer Agreement and... (United States)


    ... Center Hotel, 101 West Fayette Street, Baltimore, MD 21201. Registration and Special Accommodations... drugs for applicable dates of service except for those dates of service after the marketing end date... electronically submitted to the FDA if such marketing end date was submitted to the FDA prior to such date. (g...

  17. 75 FR 17126 - Foreign-Trade Zone 26-Atlanta, Georgia, Application for Expansion and Reorganization under... (United States)


    ... Richmond County, which is adjacent to the Colombia, South Carolina Customs and Border Protection port of... (Fayette County); Site 3 (85 acres) -- Canton- Cherokee County Business and Industrial Park, Brown... 411-acre Green Valley Industrial Park, located at the intersection of Green Valley Road and State...

  18. Attendance structure and economic impact of the National Road Festival (United States)

    Charles H. Strauss; Bruce E. Lord


    The National Road Festival is a four-day event scheduled in mid-May along a 90-mile section of U.S. Route 40 within the southwestern Pennsylvania counties of Washington, Fayette, and Somerset. This 26-year tradition commemorates America's first federally funded highway and includes over 30 recreational sites and community attractions. The Festival provides a...

  19. 77 FR 76061 - West Virginia; Major Disaster and Related Determinations (United States)


    ... resulting from Hurricane Sandy during the period of October 29 to November 8, 2012, is of sufficient... designated as adversely affected by this major disaster: Barbour, Boone, Braxton, Clay, Fayette, Kanawha... Assistance Grant; 97.048, Disaster Housing Assistance to Individuals and Households In Presidentially...

  20. 75 FR 11538 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification... (United States)


    ... Section 7A of the Clayton Act, 15 U.S.C. 18a, as added by Title II of the Hart-Scott-Rodino Antitrust..., Inc. 20100400 G Carl C. Icahn G Regeneron Pharmaceuticals, Inc. G Regeneron Pharmaceuticals, Inc...

  1. 77 FR 48542 - United States (United States)


    ... litigation.'' United States v. Armour and Co., 402 U.S. 673, 681 (1971). Section 5 of the Clayton Act... relief in consent judgment that contained recitals in which defendants asserted their innocence); Armour...

  2. 75 FR 49523 - National Register of Historic Places; Notification of Pending Removal of Listed Property (United States)


    ... for removal has been made for the following resource: MISSOURI St. Louis [Independent City] Medart's, 7036 Clayton Ave., St. Louis, 09000410 [FR Doc. 2010-20091 Filed 8-12-10; 8:45 am] BILLING CODE P ...

  3. 76 FR 68188 - Notice of Proposals To Engage in or To Acquire Companies Engaged in Permissible Nonbanking... (United States)


    ... Bank Holding Company Act (12 U.S.C. 1843) (BHC Act) and Regulation Y, (12 CFR Part 225) to engage de... (Chapelle Davis, Assistant Vice President) 1000 Peachtree Street NE., Atlanta, Georgia 30309: 1. Clayton...

  4. 77 FR 25735 - Notice of Proposed Reinstatement of Terminated Oil and Gas Leases NMNM 112882 and NMNM 112883 (United States)


    ... lessee Clayton Williams Energy, Inc., for lands in Eddy County, New Mexico. The petition was filed on... Mineral Leasing Act of 1920 (30 U.S.C. 188). We are proposing to reinstate leases NMNM 112882 and NMNM...

  5. 76 FR 18779 - National Register of Historic Places; Notification of Pending Nominations and Related Actions (United States)


    ..., 11000222 MISSOURI St. Louis County Medart's 7036 Clayton Ave., St. Louis, 09000410 MONTANA Carbon County... Lake City, 11000234 Sanpete County Poulson--Hall House, 90 S. 100 East, Manti, 11000235 [FR Doc. 2011...


    African Journals Online (AJOL)

    . kg. OPSOMMING. 'n. Ondersoek na die voedingswaarde van Cynodon aethiopicus Clayton et Harlan (stergras) en Penniserum chndestinum Hochst ex. Chiov (kikuyu) as hooigewas vir skape is met behulp van verteringsproewe onderneem.

  7. 78 FR 37847 - Senior Executive Service (SES) Performance Review Board; Members (United States)


    ... effective on June 24, 2013. FOR FURTHER INFORMATION CONTACT: Pamela S. Pope, Office of Human Capital, Talent... Officer; Sean M. Clayton, Chief Human Capital Officer; and Micah M. Cheatham, Chief Financial Officer...

  8. Phase Field Theory and Analysis of Pressure-Shear Induced Amorphization and Failure in Boron Carbide Ceramic (United States)


    Phase Field Theory and Analysis of Pressure-Shear Induced Amorphization and Failure in Boron Carbide Ceramic by John D Clayton ARL-RP...Pressure-Shear Induced Amorphization and Failure in Boron Carbide Ceramic John D Clayton Weapons and Materials Research Directorate, ARL...and Analysis of Pressure-Shear Induced Amorphization and Failure in Boron Carbide Ceramic 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM

  9. 33 CFR Schedule III to Subpart A... - Calling-in Table (United States)


    ... 1. Name of vessel.2. Location. 14. Cross Over Island—entering sector 4 Seaway Clayton, channel 13... Vincent Seaway Clayton, channel 13 1. Name of vessel2. Location. 3. ETA Cross Over Island or river port... Lake Ontario if downbound. (68 Stat. 93-96, 33 U.S.C. 981-990, as amended and secs. 4, 5, 6, 7, 8, 12...

  10. 26 CFR 1.162-21 - Fines and penalties. (United States)


    ... (including damages under section 4A of the Clayton Act (15 U.S.C. 15a), as amended) paid to a government do... and was fined $50,000. The United States sued M Corp. under section 4A of the Clayton Act (15 U.S.C... chapter 68 of the Internal Revenue Code of 1954; (iii) Paid in settlement of the taxpayer's actual or...

  11. Teaching teamwork: an evaluation of an interprofessional training ward placement for health care students


    Morphet, Julia; Hood, Kerry; Cant, Robyn; Baulch, Julie; Gilbee, Alana; Sandry, Kate


    Julia Morphet,1 Kerry Hood,2 Robyn Cant,2 Julie Baulch,3 Alana Gilbee,3 Kate Sandry4 1School of Nursing and Midwifery, Monash University, Frankston, Victoria, Australia; 2School of Nursing and Midwifery, Monash University, Clayton, Victoria, Australia; 3Southern Clinical School, Monash University, Monash Health, Clayton, Victoria, Australia; 4Dandenong Emergency Department, Monash Health, David St, Dandenong, Victoria, Australia Abstract: The establishment of interprofessional teamwork train...

  12. Propaganda Tool: The Hollywood War Movie and Its Usurpation by TV (United States)


    Barrett, Edward W. Truth Is Our Wea on. New York: Funk and Wagnalls Company, IM53. Black, Gregory D. and Koppes, Clayton R. Hollywood Goes To War: How...34Propaganda," The World Book Encyclopedia , 1976, Vol. 15, p. 725 (hereafter referred to as "Propaganda"). 2. John M. Shotwall, LTc, Fog of War: An...34 The World Book Encyclopedia , 1976, Vol. 15, p. 725 (hereafter referred to as "Propaganda"). 3. Gregory D. Black and Clayton R. Koppes, Hollywood

  13. Advancing Replicable Solutions for High-Performance Homes in the Southeast

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, S. G. [Partnership for Home Innovation, Upper Marlboro, MD (United States). Southface Energy Inst.; Sweet, M. L. [Partnership for Home Innovation, Upper Marlboro, MD (United States). Southface Energy Inst.; Francisco, A. [Partnership for Home Innovation, Upper Marlboro, MD (United States). Southface Energy Inst.


    The work presented in this report advances the goals of the U.S. Department of Energy Building America program by improving the energy performance of affordable and market-rate housing. Southface Energy Institute (Southface), part of the U.S. Department of Energy Building America research team Partnership for Home Innovation, worked with owners and builders with various market constraints and ultimate goals for three projects in three climate zones (CZs): Savannah Gardens in Savannah, Georgia (CZ 2); JMC Patrick Square in Clemson, South Carolina (CZ 3); and LaFayette in LaFayette, Georgia (CZ 4). This report documents the design process, computational energy modeling, construction, envelope performance metrics, long-term monitoring results, and successes and failures of the design and execution of these high-performance homes.

  14. Fungicide efficacy in peach rusty spot control in Serbia


    Dolovac Nenad; Miletić Novica; Aleksić Goran; Savić Dušan; Živković Svetlana; Trkulja Nenad; Bulajić Aleksandra


    Rusty Spot has long been known as a harmful peach disease in many parts of the world. During the past several years, rusty spot infection of the late-maturing peach cultivars (Summerset, Suncrest, Fayette and O’Henry) caused significant yield losses in Serbia. Although the etiology of the disease is still unknown, there are numerous studies attempting to set a strategy for its control and recommend appropriate chemical and other peach protection methods. Ho...

  15. ANIMAtion Studio


    Fraidoon, Noora


    Form, space, rhythm, order, symmetry, balance, repetition, proportion and scale are few from a long checklist of principles that, if followed carefully by the designer, will result in "beautiful" architecture, or so I was told. However, what exactly is "beautiful"? In his book "The beautiful necessity" (1910, p.34) Claude Fayette Bragdon suggests that "Beauty is the name we give to truth we cannot understand". This statement implies that there is a hidden quality within each building, or ev...

  16. Annual Soil Temperature Wave at Four Depths in Southwestern Wisconsin (United States)

    Richard S. Sartz


    Soil temperature was measured for a year on a southeast-facing slope of 25 percent, latitude 43 degrees 50 minutes N. The spring-summer cover was unmowed alfalfa-bluegrass meadow, the fall-winter cover, meadow stubble. Snow cover was light or absent. The soil was Fayette silt loam, valley phase. The annual temperature wave at all depths followed the air temperature...

  17. Synthesis of Polypropylene/Organoclay Nanocomposites via In Situ Polymerization with Improved Thermal and Dynamic-Mechanical Properties. (United States)

    Almeida, Lidiane A; Marques, Maria de Fátima V; Dahmouche, Karim


    Preparation of polypropylene/clay nanocomposites via in situ polymerization is investigated. MgCl2/organophilic clay bi-supported Ziegler-Natta catalysts were used to prepare these nanocomposites. Three organophilic clays (Cloisite 30B, Cloisite 15A, and Claytone HY) were used as support and reinforcement agents. The nanostructure of the composites was characterized by X-ray diffraction. The results showed that the most active catalyst was that with clay having high inter-layer spacing without functional OH groups. Moreover, the silica layers of the clays (Cloisite 15A and Claytone HY) in these polypropylene/clay nanocomposites were exfoliated and well dispersed in the polypropylene matrix. Differential scanning calorimetric was used to investigate both melting and crystallization temperatures, as well as the crystallinity of the nanocomposite samples. These results showed that Cloisite 15A and Claytone HY acted as nucleating agents in the process of crystallization of polypropylene. Thermogravimetric analysis showed that Cloisite 15A and Claytone HY promoted an increase in resistance to thermal degradation. Dynamic-mechanical analysis showed that nanocomposites presented an increase in the storage modulus. Furthermore, Cloisite 15A and Claytone HY promoted an increase in glass transition temperature. Small-angle X-ray scattering analysis was used to determine how clay and its concentration influence the size of the polymer nanocrystals.

  18. Validation and Application of Pharmacokinetic Models for Interspecies Extrapolations in Toxicity Risk Assessments of Volatile Organics (United States)


    100 %unsiliotms ffCcmtlnt.n mesh). Operating temperatures were 200’C. injection Nleiahelicrie 0.1 IS min*i Port: 350*C. LCD detector. and VSC . column...R.D. (1968). The toxicology ofl 1, Itnchlo breathing valves. LobAntm. Sci. 29, 323-329. rocthane. Ann . Occrsp. lly, 11, 71-79. MoNsrR, A. C, BcsERSasA...38CI tracer bromineand iodine. In Patty’s lndustrialilsgiene and techniques. Ann . Occup 11y. 1, 273-282. Toxicology (G3. D. Clayton and E. Clayton. Edo

  19. Statistical and Epistemological Issues in the Evaluation of Treatment Efficacy of Pharmaceutical, Psychological, and Combination Treatments for Women's Sexual Desire Difficulties. (United States)

    Chivers, Meredith L; Basson, Rosemary; Brotto, Lori A; Graham, Cynthia A; Stephenson, Kyle R


    We were grateful to receive responses from Leonore Tiefer, Anita Clayton and Robert Pyke, and Richard Balon and Robert Segraves, to our commentary (Brotto et al., 2016 ) on Pyke and Clayton ( 2015 ). These commentaries raise a number of substantive statistical and epistemological issues relating to the evaluation of treatment efficacy in pharmaceutical, psychological, and combination treatments for sexual desire difficulties and caution researchers to remain mindful of sources of bias as we do the science. In what follows, we discuss each of these issues in turn in hopes of encouraging our field to adopt the highest possible standards when carrying out and interpreting treatment outcome research.

  20. Australian Alps: Kosciuszko, Alpine and Namadgi National Parks (Second Edition

    Directory of Open Access Journals (Sweden)

    Nicole Porter


    Full Text Available Reviewed: Australian Alps: Kosciuszko, Alpine and Namadgi National Parks (Second Edition By Deidre Slattery. Clayton South, Australia: CSIRO Publishing, 2015. xvii + 302 pp. AU$ 45.00, US$ 35.95. ISBN 978-1-486-30171-3.

  1. Disease: H01902 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available MID:23680354 ... AUTHORS ... Rohrbach M, Spencer HL, Porter LF, Burkitt-Wright EM, Bu...n M, Madden C, Dodds A, Chandler KE, Banka S, Au L, Clayton-Smith J, Khan N, Biesecker LG, Wilson M, Rohrbac

  2. Walla Walla District History: Part II: 1970-1975 (United States)


    was headed by LTC Clayton A. Rust for a short time. He was succeeded by Joseph F. Skidmore and in 1955 by James D. Van Santo This office principally...SYSTEMS BRANCH Page 3 I TRAINING & DEVElOPMENT BR I Pogo 3 ... Jehn N. Fox Chlol ’Cecll L. Ashley Chlol I Milton L. Bolr Chlel I u - Bldg 624-E. , 155

  3. 77 FR 20419 - United States (United States)


    ... addition, Humana and Arcadian each have an established brand and positive reputation in the relevant... are ``sections of the country'' within the meaning of Section 7 of the Clayton Act: Mohave and Yavapai...]Hirschman Index The term ``HHI'' means the Herfindahl[hyphen]Hirschman Index, a commonly accepted measure of...

  4. 75 FR 8945 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification... (United States)


    ... February 2, 2010. Section 7A of the Clayton Act, 15 U.S.C. 18a, as added by Title II of the Hart-Scott... Markit Group Holdings Limited. G Markit Group Holdings Limited. 21-JAN-10 20100288 G Carl C. Icahn. G...

  5. Mapping the Contours of Neoliberal Educational Restructuring: A Review of Recent Neo-Marxist Studies of Education and Racial Capitalist Considerations (United States)

    Pierce, Clayton


    In this article Clayton Pierce reviews three books representative of the recent neo-Marxist literature on education: David Blacker's "The Falling Rate of Learning and the Neoliberal Endgame," John Marsh's Class Dismissed: "Why We Cannot Teach or Learn Our Way out of Inequality," and Pauline Lipman's "The New Political…

  6. Numerical Simulation of Ballistic Impact of Layered Aluminum Nitride Ceramic (United States)


    ARL-TR-7416 ● SEP 2015 US Army Research Laboratory Numerical Simulation of Ballistic Impact of Layered Aluminum Nitride Ceramic...of Ballistic Impact of Layered Aluminum Nitride Ceramic by JD Clayton Weapons and Materials Research Directorate, ARL...Numerical Simulation of Ballistic Impact of Layered Aluminum Nitride Ceramic 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6

  7. Disruptive Technology: What Is It? How Can It Work for Professional Writing? (United States)

    Godwin, Mary


    Writing in 1995 for the "Harvard Business Review" audience of executive managers, Harvard business professor Clayton Christensen coined the term "disruptive technologies" to describe innovations that improve a product, service, or operation in ways wholly unanticipated by leaders of existing markets. Christensen's economic theory offers a launch…

  8. Fulltext PDF

    Indian Academy of Sciences (India)


    Orion stars have found large value of R ~ 5.2 (Breger et al. 1981; Cardelli & Clayton. 1988). These large values of R have been attributed to large grain sizes (≥ 0.2 µm) in these regions. These grains could have grown larger than normal size through either accretion or coagulation (Mathis 1990). If the grains have grown ...

  9. Atmospheric Renewable Energy Research, Volume 5 (Solar Radiation Flux Model) (United States)


    ARL-TR-8155 ● SEP 2017 US Army Research Laboratory Atmospheric Renewable Energy Research, Volume 5 (Solar Radiation Flux Model... Energy Research, Volume 5 (Solar Radiation Flux Model) by Clayton Walker and Gail Vaucher Computational and Information Sciences Directorate, ARL...2017 June 28 4. TITLE AND SUBTITLE Atmospheric Renewable Energy Research, Volume 5 (Solar Radiation Flux Model) 5a. CONTRACT NUMBER ROTC Internship

  10. Interdisciplinary Health Team Care: Proceedings of the Annual Conference (8th, Columbus, Ohio, September 18-20, 1986). (United States)

    Brunner, Marjorie L., Ed.; Casto, R. Michael, Ed.

    The following are among the 40 papers included in this proceedings: "Code of Ethics for Interdisciplinary Care" (Thomasma); "Training Model for Increasing Team Excellence and Efficiency" (Clayton, Lund); "Organizational Structures of Health Care Teams" (Farrell, Schmitt, Heinemann); "Nutrition Support Practice" (Johnson); "Dividing up the Work on…

  11. STAR Performance with SPEAR (Signal Processing Electronic Attack RFIC) (United States)


    STAR Performance with SPEAR ( Signal Processing Electronic Attack RFIC) Luciano Boglione, Clayton Davis, Joel Goodman, Matthew McKeon, David...Parrett, Sanghoon Shin and Naomi Walker Naval Research Laboratory Washington, DC, 20375 Figure 1: The Signal Processing Electronic Attack RFIC...SPEAR) system. Abstract: The Signal Processing Electronic Attack RFIC (SPEAR) is a simultaneous transmit and receive (STAR) system capable of

  12. Draft Environmental Impact Statement Disposal and Reuse of Carswell AFB, Texas. Disposal and Reuse of Carswell Air Force Base, Texas (United States)


    State University, Northridge M.S., 1990, Experimental Psychology, California State University, Northridge Years of Experience: 6 Christopher Clayton...Biology, California State University, San Bernardino Years of Experience: 10 Christopher D. Hobbins, HQ AFCEE, Base Closure Restoration Division, Team...Texas. Bureau of Economic Geology, 1987. Geologic Atlas of Texas, Dallas Sheet, The University of Texas at Austin, Austin, Texas. Camp Dresser

  13. Download this PDF file

    African Journals Online (AJOL)

    In similar studies in Colombia, Doll and. Piedrahita (1976) recorded Cyperus rotundus L. (purple nutsedge), Rottboellia exaltata (Lour). Clayton (Raoul grass), Sorghum halepense L. Pers (Johnson grass) and Ipomoea sp- (morning glory) to be the most noxious weeds in cassava fields. In south western Nigeria, Onochie.

  14. South African Journal of Philosophy - Vol 24, No 3 (2005)

    African Journals Online (AJOL)

    Technology and the Time-Image: Deleuze and Postmodern Subjectivity · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Clayton Crockett, 176-188. ...

  15. Closing the Gap: Using Graduate Attributes to Improve Indigenous Education (United States)

    Anderson, Peter J.; Atkinson, Bernadette


    Peter J. Anderson and Bernadette Atkinson teach Indigenous and Traditionally Education in a Global World as a fourth year unit in the Faculty of Education at Monash University, Clayton. This paper is a self reflective piece of work where they discuss the use of graduate attributes relating to Indigenous Education, put forward by the Australian…

  16. A Murine Model of Genetic and Environmental Neurotoxicant Action (United States)


    Langston JW, Forno LS, Rebert CS, Irwin I (1984) Selective nigral tox- Widdowson PS, Famworth MJ, Simpson MG, Lock EA (1996a) Influence of icity after... plexus papillomas. Journal of Neuroscience Research. 24(1):115-22, 6. Clayton DF and George JM. (1999) Synucleins in synaptic plasticity and

  17. 76 FR 28080 - United States v. Unilever N.V., et al.; Proposed Final Judgment and Competitive Impact Statement (United States)


    ... marketing strategies in those different sales channels, and (iv) the average price of hairspray sold in... salons and uses different marketing strategies in those different sales channels, and (iv) the average... Clayton Act, 15 U.S.C. Sec. 18, and result in higher prices for consumers in these markets. The United...

  18. SHORT COMMUNICATION Serological profiles of Herpes simplex ...

    African Journals Online (AJOL)


    Journal of Infectious Diseases, 185, 45-52. Watson-Jones, D., Weiss, H.A., Rusizoka, M., Changalucha, J., Baisley, K., Mugeye, K., Tanton, C.,. Ross, D., Everett, D. & Clayton, T. (2008) Effect of herpes simplex suppression on incidence of HIV among women in Tanzania. New England Journal of Medicine 358: 1560-1571.

  19. Wild psychometrics: Evidence for ?general? cognitive performance in wild New Zealand robins, Petroica longipes


    Hackett, Paul M. W.


    A commentary on\\ud Wild psychometrics: Evidence for ‘general’ cognitive performance in wild New Zealand robins, Petroica longipes\\ud \\ud by Shaw, R. C., Boogert, N. J., Clayton, N. S., and Burns, K. C. (2015). Anim. Behav. 109, 101–111. doi: 10.1016/j.anbehav.2015.08.001

  20. Kaitstud tööd 2013 : [doktori- ja magistriväitekirjad

    Index Scriptorium Estoniae


    Doktoritööd kaitses Anu Sarv; magistritööd Anto Alasepp, Ott Puumeister, Marili Pärtel, Maarja Yano, Eva Väljaots, Ana Koncul, Derek Clayton Jenkins, Mark Richard Lemon, Matthew Campanella, Montana Jean Salvoni, Muzayin Arifin Nazaruddin, Oleg Sobchuk

  1. Taba trende enne teisi / Harli Uljas

    Index Scriptorium Estoniae

    Uljas, Harli


    Autor tutvustab maailmakuulsa innovatsiooniteoreetiku Clayton M. Christenseni innovatsiooniteooriat ning selle kasutamist võimalike turumuutuste ennustamisel. Kommenteerib konsultatsioonifirma Ajutrust konsultant Tiit Jürimäe. Vt. samas: Kopp ees; Zara tabab trende klubidest; Kui suureks peab kasvama lennujaam?; Kuidas jaotab kliente maailmakuulus trendipüüdja Anne-Lise Kjaer

  2. 14 CFR 303.05 - Applications requesting antitrust immunity. (United States)


    ... the provisions of sections 4, 4a and 4c of the Clayton Act, 15 U.S.C. 15, 15a, 15c. Each application... immunity granted does not operate under section 558 of Administrative Procedure Act, 5 U.S.C. 558(c), to...

  3. Effects of seed and seedling predation by small mammals on ...

    African Journals Online (AJOL)


    Mar 4, 1991 ... S.-Afr. Tydskr. Dierk. 1992,27(2). Effects of seed and seedling predation by small mammals on seedling recruitment of Protea neriifolia in Swartboskloof, Cape Province. S.A. Botha .... Midgley & Clayton 1990). As the vegetation .... Trap stations on permanent s~1I mam~ltr~plng grid In Iynbos o Trap stations ...

  4. RESEARCH NOTE Aniridia due to a novel microdeletion affecting ...

    Indian Academy of Sciences (India)

    Andreas Syrimis

    Fantes J., Redeker B., Breen M., Boyle S., Brown J., Fletcher J. et al. 1995 Aniridia-associated cytogenetic rearrangements suggest that a position effect may cause the mutant phenotype. Hum. Mol Genet. 4(3), 415-422. Firth H. V., Richards S. M., Bevan A. P., Clayton S., Corpas M., Rajan D. et al. 2009 DECIPHER:.

  5. Chromosome studies on African plants. 11. The tribe Andropogoneae (Poaceae: Panicoideae

    Directory of Open Access Journals (Sweden)

    J. J. Spies


    Full Text Available Representative specimens of various species of the genera  Andropogon L.,  Cymbopogon Spreng.,  Elionurus Kunth ex Willd.,  Hyparrhenia Foum. and  Hyperthelia Clayton were cytogenetically studied. All specimens had a secondary basic chromosome number of ten. Polyploidy, either as alloploidy or segmental alloploidy. was frequent. The taxa studied represent mature polyploid complexes.

  6. Untitled

    African Journals Online (AJOL)

    van Cynodon aethiopicus Clayton et Harlan (stergras) en. Pennisetum clandestinum Hochst ex Chiov (kikuyu) as hooigewas vir skape. S. Afr. Tydskr. Veek. 11, 211. LIEBENBERG, L.C.C., 1956. Weiding en voergewasse vir die. Transvaal-streek. Boerd. S. Afr. 32, 197. LUDLOW, M.M., STOBBS, T.H., DAVIS, R. & CHARLES-.

  7. Analysis of ENSO-based climate variability in modulating drought ...

    Indian Academy of Sciences (India)

    (2009) employed Archimedean class of Clayton copula to investigate the nature of S–D–F curves of two different climatic regions in Iran due to its sim- plified structure. Song and Singh (2010) modelled bivariate joint probability distribution of drought properties in Texas using meta-elliptical class of copulas and found that ...

  8. Korte mededeling

    NARCIS (Netherlands)

    Ooststroom, van S.J.


    Beckeropsis petiolaris (Hochst.) Fig. & De Not. in Nederland. In Gorteria 3 (4), 1966, p. 55 vermeldden Reichgelt en ik een adventieve Beckeropsis van Rotterdam, die wij met enige aarzeling als B. petiolaris bestempelden. Intussen verscheen van de hand van W. D. CLAYTON, in Hooker’s Icones

  9. 16 CFR 1211.12 - Requirements for edge sensors. (United States)


    ... accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies may be obtained from Global Engineering Documents..., 7730 Carondelet Ave., Suite 470, Clayton, MO 63105, Telephone (800) 854-7179. EC03OC91.045 Copies may...

  10. 16 CFR 2.20 - Petitions for review of requests for additional information or documentary material. (United States)


    ... Section 7A of the Clayton Act, as Amended, for Review of Requests for Additional Information or... recipient(s) of the request that the recipient has a right to discuss modifications or clarifications of the..., and shall address petitioner's efforts to obtain modification from the authorized representative. (ii...

  11. Book Review: Wildlife Conservation in Farmed Landscapes ...

    African Journals Online (AJOL)

    Book Title: Wildlife Conservation in Farmed Landscapes. Book Authors: David Lindenmayer, Damian Michael, Mason Crane, Sachiko Okada, Daniel Florance, Philip Bartion & Karen Ikin. 2016, CSIRO Publishing, Unipark Building 1 Level 1, 195 Wellington Road, Clayton, VIC 3168, Australia. 232 pages, softcover, ePDF ...

  12. 77 FR 59661 - Notice of Inventory Completion: Stanford University Archaeology Center, Stanford, CA (United States)


    ... Triangle area of Marin County, CA, by Lt. Commander Bryant and his son Clayton Bryant. The collection was... time of death or later as part of the death rite or ceremony. Pursuant to 25 U.S.C. 3001(2), there is a...

  13. Suhtesõlmed kire vastu / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-


    Sisu : Linn Ullmann. Enne kui sa uinud; Josie Lloyd, Emlyn Rees. Saame kokku; Deborah Moggach. Tulbipalavik; Victoria Clayton. Armastusest loobuja; Rosamunde Pilcher: Kaksikute tähtkujus; Hailey North. Kallis Armastuse Doktor; August Gailit. Muinasmaa; Aidi Vallik. Mis teha, Ann?; A. E. Hotchner. Papa Hemingway

  14. New Faces of Blended Learning (United States)

    Horn, Michael B.; Fisher, Julia Freeland


    The Clayton Christiansen Institute maintains a database of more than 400 schools across the United States that have implemented some form of blended learning, which combines online learning with brick-and-mortar classrooms. Data the Institute has collected over the past six months suggests three trends as this model continues to evolve and mature.…

  15. Is K-12 Blended Learning Disruptive? An Introduction to the Theory of Hybrids (United States)

    Christensen, Clayton M.; Horn, Michael B.; Staker, Heather


    The Clayton Christensen Institute for Disruptive Innovation, formerly the Innosight Institute, has published three papers describing the rise of K-12 blended learning--that is, formal education programs that combine online learning and brick-and-mortar schools. This fourth paper is the first to analyze blended learning through the lens of…

  16. Mesoscale Modeling of Nonlinear Elasticity and Fracture in Ceramic Polycrystals Under Dynamic Shear and Compression (United States)


    SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT UU 18. NUMBER OF PAGES 24 19a. NAME OF RESPONSIBLE PERSON J. D. Clayton a. REPORT...elsewhere for SiC (Lee et al., 2005), follows from a cap plasticity model formulated in the context of geomechanics (Sandler and Rubin, 1979):rections, and

  17. Application of high resolution SNP arrays in patients with congenital ...

    Indian Academy of Sciences (India)

    743,304 SNP probes, on an industry standard 1 × 3 glass slide. These oligonucleotide probes cover the whole genome with an average spatial resolution of 1148 ..... Clayton-Smith et al. (2011) showed that mice with a hypomorphic KAT6B gt/gt mutation are of nor- mal size at birth but fail to thrive and have brain develop-.

  18. 78 FR 31566 - National Vaccine Injury Compensation Program; List of Petitions Received (United States)


    ... Federal Claims No: 13-0252V. 31. William and Brenda Lehann Rodriguez on behalf of C.R., Clayton, Georgia...-0265V. 35. Scott and Caroline VanScoy on behalf of Alyssa VanScoy, Simi Valley, California, Court of...

  19. 75 FR 52006 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification... (United States)


    ...&T Inc. G Verizon Communications Inc. G Newco LLC. 12-JUN-09 20090504 G Clayton, Dubilier & Rice Fund... Metal Mining Co., Ltd. G Teck Resources Limited. G Teck-Pogo, Inc. 20090526 G Golden Gate Capital..., Inc. 06-JUL-09 20090543 G Golden Gate Capital Opportunity Fund, L.P. G SoftBrands, Inc. G SoftBrands...


    African Journals Online (AJOL)



    Jun 1, 2014 ... Keywords: Bird Louse, Kano Sub-urb areas, Menacanthus cornutus, Poultry, Prevalence ... including retarded growth, low egg production and ..... Bush, S. E. and Clayton, D. H.. (2005). Correlated evolution of host and parasite body size: Tests of Harrison's rule using birds and lice. Evolution, 59: 1744-.

  1. Kirjad ja kriisid / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-


    Sisu : Maimu Veske. Continental; Maeve Haran. Tangot tantsitakse kahekesi; Zana Muhsen. Müüdud; Ingo Schulze. 33 õnnehetke; Alistair MacLean. Karusaar; Suur uneraamat, koost. Raisa Vuohelainen; Arbujad, koost. Ants Oras; Friedrich Weissensteiner. Kuulsad enesetapjad; Peter A. Clayton. Vaaraode kroonika; Lillede keel

  2. Virtual vs. Concrete Manipulatives in Mathematics Teacher Education: Is One Type More Effective than the Other? (United States)

    Hunt, Annita W.; Nipper, Kelli L.; Nash, Linda E.


    Are virtual manipulatives as effective as concrete (hands-on) manipulatives in building conceptual understanding of number concepts and relationships in pre-service middle grades teachers? In the past, the use of concrete manipulatives in mathematics courses for Clayton State University's pre-service middle grades teachers has been effective in…

  3. A College Administrator's Framework to Assess Compliance with Accreditation Mandates (United States)

    Davis†, Jerry M.; Rivera, John-Juan


    A framework to assess the impact of complying with college accreditation mandates is developed based on North's (1996) concepts of transaction costs, property rights, and institutions; Clayton's (1999) Systems Alignment Model; and the educational production function described by Hanushek (2007). The framework demonstrates how sought…

  4. Ending the tobacco problem: a blueprint for the nation

    National Research Council Canada - National Science Library

    Bonnie, Richard J; Stratton, Kathleen R; Wallace, Robert B


    .... We wish to thank the following individuals for their review of this report: Lois Biener, Ph.D., University of Massachusetts, Boston Richard Clayton, Ph.D., University of Kentucky Phillip Cook, Ph.D., Duke University Gordon DeFriese, Ph.D., University of North Carolina Paul Fischer, M.D., Center for Primary Care Gary Giovino, Ph.D., State University ...

  5. 78 FR 53457 - Phoebe Putney Health System, Inc., et al.; Analysis of Proposed Agreement Containing Consent... (United States)


    ... commercial or financial information which . . . is privileged or confidential,'' as discussed in Section 6(f... provision of inpatient general acute-care hospital services sold to commercial health plans in Albany and... the Clayton Act, 15 U.S.C. 26, in the U.S. District Court for the Middle District of Georgia. On June...

  6. Verifiable Task Assignment and Scheduling Controller (United States)


    AFRL-RH-WP-TR-2017-0045 Verifiable Task Assignment and Scheduling Controller Clayton Rothwell Infoscitex Corporation...Chief, Supervisory Control Cognition Branch Supervisory Control and Cognition Branch Warfighter Interface Division //signed// KRISTOFFER A...information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM

  7. supp23.doc

    Indian Academy of Sciences (India)

    a Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, Maharashtra-400076, India. b School of Chemistry, University of Monash, Clayton, Victoria-3800, Australia. Crystallogrpahic information file for complex 1. data_test. _audit_creation_method SHELXL-97. _chemical_name_systematic. ; ?


    Directory of Open Access Journals (Sweden)



    Full Text Available Value at Risk explains the magnitude of the worst losses occurred in financial products investments with a certain level of confidence and time interval. The purpose of this study is to estimate the VaR of portfolio using Archimedean Copula family. The methods for calculating the VaR are as follows: (1 calculating the stock return; (2 calculating descriptive statistics of return; (3 checking for the nature of autocorrelation and heteroscedasticity effects on stock return data; (4 checking for the presence of extreme value by using Pareto tail; (5 estimating the parameters of Achimedean Copula family; (6 conducting simulations of Archimedean Copula; (7 estimating the value of the stock portfolio VaR. This study uses the closing price of TLKM and GGRM. At 90% the VaR obtained using Clayton, Gumbel, Frank copulas are 0.9562%, 1.0189%, 0.9827% respectively. At 95% the VaR obtained using Clayton, Gumbel, Frank copulas are 1.2930%, 1.2522%, 1.3152% respectively. At 99% the VaR obtained using Clayton, Gumbel, Frank copulas are 2.0327%, 1.9164%, is 1.8678% respectively. In conclusion estimation of VaR using Clayton copula yields the highest VaR.

  9. Quantitative and Qualitative Research in HSDD: The Difference Between Testing Theory and Generating New Theories. (United States)

    Clayton, Anita H; Pyke, Robert E


    Tiefer (2017) criticized our recent analysis of psychological treatment trials for HSDD (Pyke & Clayton, 2015) on what she claims to be scientific and "political" grounds. In the same letter, she alleged that we, and, by extension, the U.S. Food and Drug Administration, promoted drugs to the detriment of psychological treatment of female sexual problems. Such accusations require a serious response.

  10. Aerobic biodegradation of butanol and diesel oil blends | Mariano ...

    African Journals Online (AJOL)

    Aerobic biodegradation of butanol and diesel oil blends. Adriano Pinto Mariano, Richard Clayton Tomasella, Clara Di Martino, Eduardo Beraldo Morais, Rubens Maciel Filho, Mirna Helena Regali Seleghim, Jonas Contiero, Sâmia Maria Tauk Tornisielo, Dejanira de Franceschi de Angelis ...

  11. New Fellows and Honorary Fellow

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1956 Honorary. Urey, Prof. Harold Clayton Nobel Laureate (Chemistry) - 1934. Date of birth: 29 April 1893. Date of death: 5 January 1981. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three ...

  12. Assessing High Impact Practices Using NVivo: An Automated Approach to Analyzing Student Reflections for Program Improvement (United States)

    Blaney, Jennifer; Filer, Kimberly; Lyon, Julie


    Critical reflection allows students to synthesize their learning and deepen their understanding of an experience (Ash & Clayton, 2009). A recommended reflection method is for students to write essays about their experiences. However, on a large scale, such reflection essays become difficult to analyze in a meaningful way. At Roanoke College,…

  13. The effect of transverse bed slope and sediment mobility on bend sorting

    NARCIS (Netherlands)

    Weisscher, S.A.H.; Baar, A.W.; Uijttewaal, W.S.J.; Kleinhans, MG; Hoitink, A.J.F.; de Ruijsscher, T.V.; Geertsema, T.J.; Makaske, B.; Wallinga, J.; Candel, J.H.J.; Poelman, J.


    Lateral sorting (= bend sorting) is observed in  natural meanders, where the inner and outer  bend are fairly fine and coarse, respectively  (e.g. Julien and Anthony, 2002; Clayton and  Pitlick, 2007). This is caused by the mass  differences between grains on a

  14. Parents' Conceptions of School Readiness, Transition Practices, and Children's Academic Achievement Trajectories (United States)

    Puccioni, Jaime


    The author empirically tests the conceptual model of academic socialization, which suggests that parental cognitions about schooling influence parenting practices and child outcomes during the transition to school (Taylor, Clayton, & Rowley, 2004). More specifically, the author examines associations among parents' conceptions of school…

  15. Physico-chemical characteristics of Jharkhand and West Bengal ...

    Indian Academy of Sciences (India)

    Department of Earth Sciences, University of Florence, Via La Pira 4, I-50121 Firenze, Italy. IITB-Monash Research Academy, Indian Institute of Technology Bombay, Mumbai 400 076, India. Civil Engineering Department, Monash University, Clayton, Melbourne 3800, Australia. King Saud University, College of Engineering ...

  16. 78 FR 57131 - Membership of the NOAA Performance Review Board (United States)


    ... Human Resources Management, U.S. Department of Commerce. Alternates: Ciaran M. Clayton Director of... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration Membership of the NOAA... Commerce (DOC). ACTION: Notice of Membership of the NOAA Performance Review Board (PRB). SUMMARY: In...

  17. Advancing Replicable Solutions for High-Performance Homes in the Southeast

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, S. G. [Southface Energy Inst., Upper Marlboro, MD (United States); Sweet, M. L. [Southface Energy Inst., Upper Marlboro, MD (United States); Francisco, A. [Southface Energy Inst., Upper Marlboro, MD (United States)


    Southface Energy Institute (Southface) partnered with owners and/or builders with various market constraints and ultimate goals for three projects in different climate zones: Savannah, GA (CZ 2), Clemson, SC (CZ 3), and LaFayette, GA (CZ 4). This report documents the design process, computational energy modeling, construction, envelope performance metrics, long-term monitoring results, and successes and failures of the design and execution of these high performance homes. The three bedroom/two bathroom test home in Savannah Gardens on an elevated slab foundation has a semi-conditioned, encapsulated attic. A neighboring home built to EarthCraft specifications was also monitored as a control for exterior foam insulation and a heat pump water heater (HPWH). For the JMC Patrick Square, a single-story project in Clemson, the small-scale production builder wanted to increase their level of energy efficiency beyond their current green building practices, including bringing ducts into conditioned space. Through a combination of upgrade measures the team met this goal and achieved many Zero Energy Ready Home requirements. LaFayette Housing Authority undertook a development of 30 affordable rental housing units in 15 duplexes in LaFayette, GA. Because they would be long-term owners, their priorities were low utility bills for the residents and durable, maintainable buildings. The team employed BEopt to optimize buildling envelope and systems choices, including 2x6 advanced framed walls, insulated slab, and heat pump water heater in a utility closet which was ducted to/from an encapsulated attic.

  18. Building America Case Study: Savannah Gardens, Savannah, Georgia

    Energy Technology Data Exchange (ETDEWEB)


    Southface Energy Institute (Southface) partnered with owners and/or builders with various market constraints and ultimate goals for three projects in different climate zones: Savannah, GA (CZ 2), Clemson, SC (CZ 3), and LaFayette, GA (CZ 4). This report documents the design process, computational energy modeling, construction, envelope performance metrics, long-term monitoring results, and successes and failures of the design and execution of these high performance homes. The three bedroom/two bathroom test home in Savannah Gardens on an elevated slab foundation has a semi-conditioned, encapsulated attic. A neighboring home built to EarthCraft specifications was also monitored as a control for exterior foam insulation and a heat pump water heater (HPWH). For the JMC Patrick Square, a single-story project in Clemson, the small-scale production builder wanted to increase their level of energy efficiency beyond their current green building practices, including bringing ducts into conditioned space. Through a combination of upgrade measures the team met this goal and achieved many Zero Energy Ready Home requirements. LaFayette Housing Authority undertook a development of 30 affordable rental housing units in 15 duplexes in LaFayette, GA. Because they would be long-term owners, their priorities were low utility bills for the residents and durable, maintainable buildings. The team employed BEopt to optimize building envelope and systems choices, including 2x6 advanced framed walls, insulated slab, and heat pump water heater in a utility closet which was ducted to/from an encapsulated attic.

  19. Obtaining DDF Curves of Extreme Rainfall Data Using Bivariate Copula and Frequency Analysis

    DEFF Research Database (Denmark)

    Sadri, Sara; Madsen, Henrik; Mikkelsen, Peter Steen


    , situated near Copenhagen in Denmark. For rainfall extracted using method 2, the marginal distribution of depth was found to fit the Generalized Pareto distribution while duration was found to fit the Gamma distribution, using the method of L-moments. The volume was fit with a generalized Pareto...... with duration for a given return period and name them DDF (depth-duration-frequency) curves. The copula approach does not assume the rainfall variables are independent or jointly normally distributed. Rainfall series are extracted in three ways: (1) by maximum mean intensity; (2) by depth and duration...... distribution and the duration was fit with a Pearson type III distribution for rainfall extracted using method 3. The Clayton copula was found to be appropriate for bivariate analysis of rainfall depth and duration for both methods 2 and 3. DDF curves derived using the Clayton copula for depth and duration...

  20. Na ratunek teologii – Philipa Claytona koncepcja emergentnego umysłu

    Directory of Open Access Journals (Sweden)

    Tomasz Maziarka


    Full Text Available New worldview that arose from a number of important findings of science, including the Darwinian theory of evolution as well as the Big Bang theory, calls for a redefinition of the human place in the world of nature. Human mind, with its characteristic self-consciousness, is facing a difficult problem of understanding of his own nature as well as clarifying its relationship with the realm of the physical world. According to Philip Clayton, the correct answer to the question of the relation of mind to body (mind-body problem is given by the concept of emergentism. While taking his arguments from modern science and philosophy, Clayton claims that the mind – causally active mental properties – is a valuable result of the evolution that has occurred through the emergence, and its special feature, i.e. rationality, sheds new light on attempts of the ultimate understanding of reality.

  1. Negative Return-Volume Relationship in Asian Stock Markets: Figarch-Copula Approach

    Directory of Open Access Journals (Sweden)

    Muhammad Naeem


    Full Text Available We explore the potential dependence among different Asian stock markets, using several different statistical models. Extreme return-volume dependence in Hong Kong Seng Index, Bombay Stock Exchange, Indonesia Composite Index and Bursa Malaysia has been examined by using FIGARCH-Copula and GARCH-Copula approach. We have used Gaussian, Student-t, Frank, Clayton, Survival Clayton and Gumbel copulas. Based on Akaike information criterion (AIC, we found that using FIGARCH model for return series improves the results of copula parameter estimation. According to our finding, Hong Kong and Indian stock indices showed weak upper tail dependence between return and volume. Further, we have found that the extremely low returns for Malaysia and Indonesia stock indices are followed by high volumes, providing evidence of leverage effect. Our investigation shows that Malaysia and Indonesia stock indices are sensitive to bad news rather than good news.

  2. The Renaissance way

    International Nuclear Information System (INIS)

    Harvie, W.


    The remarkable success of Renaissance Energy Ltd., of Calgary, under the leadership of its CEO, Clayton Woitas, was described. Clayton Woitas was selected as the 'Producer of the Year' for leading his company to a most successful year by following a simple set of fundamentals with unrelenting dedication and discipline. The achievements of the company in drilling a large number of small prospect wells in the plains areas of Alberta, its single-minded devotion to low cost production, avoidance of the fashionable, concentration on small-yield areas of both Alberta and Saskatchewan, its belief in a high level of delegation, and faith and confidence in its people, were described as the explanation for the company's outstanding success

  3. Modeling dependence structure between stock market volatility and sukuk yields: A nonlinear study in the case of Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Nader Naifar


    Full Text Available The aim of this paper is to investigate the dependence structure between sukuk (Islamic bonds yields and stock market (returns and volatility in the case of Saudi Arabia. We consider three Archimedean copula models with different tail dependence structures namely Gumbel, Clayton, and Frank. This study shows that the sukuk yields exhibit significant dependence only with stock market volatility. In addition, the dependence structure between sukuk yields and stock market volatility are symmetric and linked with the same intensity.

  4. New Mobile Technologies

    DEFF Research Database (Denmark)

    Tan, Su-En; Henten, Anders


    This paper takes a look at Clayton Christensen 's theory of disruptive technologies and how Christensen's theory relates to other innovation theories. It also proposes a new layer of analysis to this theory to better link the technology analysis to the market analysis of any given technology...... product. This layer suggests that complementarity and substitutability are important criteria for technologies to be market disruptions or sustaining changes....

  5. Integration of Experience API Into CDET’s E-Learning (United States)


    hse_ethesis_12435.pdf Kuhlmann, T. (2009, May 19). Are your e- learning courses pushed or pulled? [ Blog post]. Retrieved from, J. (2015, July 15). Updated e- learning definitions [ Blog post]. Retrieved from learning ...EXPERIENCE API INTO CDET’S E- LEARNING by Clayton C. MacAloney June 2016 Thesis Advisor: Man-Tak Shing Co-Advisor: Arijit Das THIS PAGE

  6. Methods for Analysis and Simulation of Ballistic Impact (United States)


    frictional effects, for example [38, 39, 23]. Fig. (1). Extended hydrodynamic theory based on dimensional analysis applied to aluminum oxide (top) and...though not always in closed form. In §3.2, another 1-D treatment is presented for analysis of planar shock waves, where steady state behavior is...Eng., Vol. 85, pp. 124–131, 2015. [11] J. Clayton, “Dimensional analysis and extended hydrodynamic theory applied to long-rod penetration of ceramics

  7. Rounding Out a Concept of Operational Art: Using Theory to Understand Operational Art’s Purpose, Structure, and Content (United States)


    20. 7 Michael Krause and R. Cody Phillips, Historical Perspectives of the Operational Art (Washington: Center of Military History , United States...Clayton Newell and Michael Krause, On Operational Art (Washington: Center of Military History , US Army, 1994), 18. 11 Kelly and Brennan, Alien, operational art theory, test it with history , and then use it to evaluate doctrine. The theory of operational art began with an examination of

  8. The use of wind data with an operational wind turbine in a research and development environment (United States)

    Neustadter, H. E.


    It is noted that in 1976, 17 candidate sites were identified for detailed evaluation as potential sites for installation of large, horizontal axis Wind Turbines (WT). Attention is given to the Mod-OA, a 200 kW WT located in Clayton, New Mexico. The discussion covers the meteorological data collected, some of the analyses based on these wind data as well as additional areas currently being investigated in relation to these data.

  9. On the general Dedekind sums and its reciprocity formula

    Indian Academy of Sciences (India)

    Introduction. For a positive integer q and an arbitrary integer h, the Dedekind sums S(h, q) is defined as: S(h, q) = ... we obtain an interesting reciprocity formula for the general Dedekind sums S(h, 1, 3,q). That is, we ..... [3] Conrey J B, Fransen Eric, Klein Robert and Scott Clayton, Mean values of Dedekind sums,. J. Number ...

  10. An audit of basic practical skills acquisition of final year medical ...

    African Journals Online (AJOL)

    Des matériaux et des procédés: Il s'agit d'une étude transversale descriptive. Structuré questionnaires ont été distribués à un ensemble (tous) de 86 étudiants médicales en ... and Clayton[1] noted that training in skills could be improved. A similar concern has been expressed by Nelson and Traub in the United States.

  11. Invariant dependence structures and Archimedean copulas

    Czech Academy of Sciences Publication Activity Database

    Durante, F.; Jaworski, P.; Mesiar, Radko


    Roč. 81, č. 12 (2011), s. 1995-2003 ISSN 0167-7152 R&D Projects: GA ČR GAP402/11/0378 Institutional research plan: CEZ:AV0Z10750506 Keywords : Archimedean copula * Tail dependence * Clayton model Subject RIV: BA - General Mathematics Impact factor: 0.498, year: 2011 dependence structures and archimedean copulas.pdf

  12. a postfoundationalist research paradigm of practical theology

    African Journals Online (AJOL)


    Jul 18, 2010 ... s e S tu d ie s. /T h e o lo g ic a l S tu d ie s HTS. Original Research. A rtic le #. 8. 4. 9. (page number not for citation purposes). A postfoundationalist research paradigm of practical theology. 5. Vol. 66 No. 2 Page 5 of 6 humans do and think' (Clayton 2006:95). Archbishop Desmond.

  13. 76 FR 8740 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification... (United States)


    ... Premerger Notification Rules Section 7A of the Clayton Act, 15 U.S.C. 18a, as added by Title II of the Hart... Partners II, L.P.; Vantage Oncology, Inc. 20110372 G Ebro Foods S.A.; Ricegrowers Limited; Ebro Foods S.A.... 20110408 G Grupo Empresarial Kaluz, S.A. de C.V.; Rockwood Holdings, Inc.; Grupo Empresarial Kaluz, S.A. de...

  14. Journal of Mormon History Vol. 19, No. 2, 1993



    LETTERS ARTICLES --"The Tongue of Angels": Glossolalia among Mormonism's Founders Dan Vogel and Scott C. Dunn, 1 --Backlash Against Formalism: Early Mormonism's Appeal in Jefferson County Marianne Perciaccante, 35 --A Black Woman in a White Man's Church: Amy E. Robbins and the Reorganization Roger D. Launius, 64 --"A Weary Traveler": The 1848-50 Diary of Zina D.H. Young Marilyn Higbee, 86 ENCOUNTER ESSAY --William Clayton: In the Shadow of Power George D. S...

  15. We Are the World: Our Responsibility to Prevent Mass Atrocities (United States)


    results the actions produce. This approach considers what produces the greatest good for the greatest number, according to John Stuart Mill. Georg...thousands of men executed and buried in mass graves, hundreds of men buried alive, men and women mutilated and slaughtered, children killed before their...Duke, and another 2,000 on the American Winona (Milton 2008, 324). John Clayton, the Chicago reporter, finally realized that he could not continue

  16. Adaptive Acquisitions: Maintaining Military Dominance By Managing Innovation (United States)


    sustaining innovation for limited resources. An example occurred at the Skunk Works Division of Lockheed Martin (LM) in the early 1970s. Despite their...tremendous success at developing innovative aircraft like the U-2 and SR-71, Skunk Works had many enemies on the LM board of directors, and...Defense Acquisition Research Journal, October 2011, 393. 7. Rich and Janos, Skunk Works, 21-22. 8. Clayton M. Christensen (Kim B. Clark Professor

  17. Japan’s Self Defense Forces After the Great East Japan Earthquake: Toward a New Status Quo (United States)


    Formation and Change (Clayton, Australia : Monash University Press, 2008), 6–7. 7 Takao’s analysis of four areas generally accepted as key...Defense, Ministry of Foreign Affairs, and Ministry of Economy, Trade, and Industry, contain English translations of important statistical information...people were left homeless from the disaster. The 1995 earthquake set the bar as the world’s most costly disaster of the time at 64 billion dollars. It

  18. Unleashed Potential: The Potential of Civil Military Support Elements in Theater Security Cooperation (United States)


    the Faculty of the U.S. Army Command and General Staff College in partial fulfillment of the requirements for the degree MASTER OF MILITARY ART ...MILITARY ART AND SCIENCE THESIS APPROVAL PAGE Name of Candidate: Major Clayton D. Curtis Thesis Title: Unleashed Potential: The Potential of Civil...Thanks to my fellow Paraguayan Army Officers, COL Jorge Mieres, COL Pablo Halaburda, and LTC Marcial Rivas for providing me important information on

  19. Southern Ocean seaweeds: A resource for exploration in food and drugs

    Digital Repository Service at National Institute of Oceanography (India)

    Dhargalkar, V.K.; Verlecar, X.N.

    this zone large brown seaweeds like Ascoseria mirabilis, D. menzeisii occur in the upper sub littoral, D. anceps in mid sub littoral andH.grandifoliusinlowerlittoral(DeLacaandLipps,1976;Amsleretal., 1995; Kloser et al., 1996; Quantino et al., 2001, 2005). H.... gandifolius occursatgreaterdepthsonfinegrainedsubstrate(WienckeandClayton, 2002; Neushul, 1965; Delepine, 1966; DeLaca and Lipps, 1976; Kloser et al., 1994, 1996; Fisher and Wiencke, 1992). This species becomes dominant in places where Desmarestia spp. cannot...

  20. Capability and core competency identification of a knowledge-based organization


    Calle, Christian


    The concept of core competencies has been discussed for the last 20 years; however concept itself has yet to be standardized. Using the theories concerning core competencies as laid out by Porter, Prahalad, and Hamel, and using a framework created by Clayton M. Christensen that adds support to the identification of core competencies through the examination of capabilities, this paper illustrates a path that supports a method of identifying core competencies through the capabilities of an orga...

  1. Tallinna Moodul = Tallinn Module / Siiri Vallner

    Index Scriptorium Estoniae

    Vallner, Siiri, 1972-


    Rahvusvahelisest disainivõistlusest Tallinna Moodul, mille eesmärk oli leida tänavamööbli süsteem, kus erinevad elemendid (kioskid, telefoniputkad, istepingid, bussiootepaviljonid, reklaamialused jne.) on seotud kontseptuaalselt ühtseks tervikuks. Osalejatest, võidutöödest. Preemiad: I - Clayton Welham, Martin Yong, London, II - Samson Adjei, Harry Dobbs, Greg Epps, London, III - Carmelo Baglivo, Luca Galofaro, Rooma. Eripreemiad (2)

  2. Perception Is Reality: Special Operations Forces In the Gray Zone (United States)


    Army SOF plan outlining the future of the organization ASG Abu Sayyaf Group CENTCOM U.S. Central Command CIA U.S. Central Intelligence ...Department of State, last modified October 31, 2013, 84 Clayton Chun, Gothic Serpent -Black Hawk Down...147 Figure 5 is an adaptation to the bureaucratic politics model, Allison and Halperin, “Bureaucratic Politics,” 148 Mark M. Lowenthal, Intelligence

  3. Improved Characterization of Far-Regional and Near-Teleseismic Phases Observed in Central Asia (United States)


    Seism . Soc. Am., 93, 1573-1605. Barani, S., G. Ferretti, M. Massa, and D. Spallarossa (2007). The waveform similarity approach to identify dependent...crustal structure, Bull. Seism . Soc. Am., 84, 1889-1902. Clayton, R., and G. McMechan (1981). Inversion of refraction data by downward continuation...R. Bulland (1998). Global teleseismic earthquake relocation with improved travel times and procedures for depth determination. Bull. Seism . Soc. Am

  4. Internet jako prostor pro sociální inovace? Analýza prostředí digitálních podob současného českého tisku


    Soukupová, Lenka


    Taking into account the theoretical approaches of Joseph Alois Schumpeter and Clayton Christensen to innovation, this case study is mapping the current Czech environment of written online media. Traditional media houses are dealing with the crisis of finances and information as generally described by Christensen, which means they are in real need for innovation yet they are not always successful. Other new incentives also appear on the market. Similarly to the situation abroad, the NGO sector...

  5. Geohydrology and susceptibility of major aquifers to surface contamination in Alabama; area 11 (United States)

    Castleberry, R.D.; Moreland, R.S.; Scott, J.C.


    This report delineates and describes the geohydrology and susceptibility of major aquifers to contamination in Butler, Conecuh, Covington, Crenshaw, Escambia, and Monroe Counties, Alabama. The major aquifers are the Pliocene-Miocene, Upper Floridan, Lisbon, Nanafalia-Clayton, and Providence-Ripley. The largest pumping centers in the area are Andalusia and Monroeville, where groundwater use is about 5 and 4 million gal/day, respectively. Estimated maximum withdrawal in 1987 for all uses in the area was about 44 million gal/day. Depressions have developed in the potentiometric surfaces of the Lisbon aquifer near Andalusia and Opp, the Nanafalia-Clayton aquifer near Luverne, Andalusia, Beatrice, and Monroeville, and the Providence-Ripley aquifer at Greenville. Significant declines in the potentiometric surfaces of the other major aquifers are not apparent. Recharge areas for all major aquifers are susceptible to contamination, but the probability of contamination of the Lisbon, Nanafalia-Clayton, and Providence-Ripley aquifers is low because the recharge areas are remote from areas of the withdrawal. The depressions in the recharge area for the Upper Floridan aquifer and the area where the Pliocene-Miocene aquifer is overlain by the gravelly sands of the Citronelle Formation are highly susceptible to contamination from the surface. (USGS)

  6. Large scale structures in liquid crystal/clay colloids

    International Nuclear Information System (INIS)

    Duijneveldt, Jeroen S van; Klein, Susanne; Leach, Edward; Pizzey, Claire; Richardson, Robert M


    Suspensions of three different clays in K15, a thermotropic liquid crystal, have been studied by optical microscopy and small angle x-ray scattering. The three clays were claytone AF, a surface treated natural montmorillonite, laponite RD, a synthetic hectorite, and mined sepiolite. The claytone and laponite were sterically stabilized whereas sepiolite formed a relatively stable suspension in K15 without any surface treatment. Micrographs of the different suspensions revealed that all three suspensions contained large scale structures. The nature of these aggregates was investigated using small angle x-ray scattering. For the clays with sheet-like particles, claytone and laponite, the flocs contain a mixture of stacked and single platelets. The basal spacing in the stacks was independent of particle concentration in the suspension and the phase of the solvent. The number of platelets in the stack and their percentage in the suspension varied with concentration and the aspect ratio of the platelets. The lath shaped sepiolite did not show any tendency to organize into ordered structures. Here the aggregates are networks of randomly oriented single rods

  7. Significant Inter-Test Reliability Across Approximate Number System Assessments

    Directory of Open Access Journals (Sweden)

    Nicholas Kurshan Dewind


    Full Text Available The approximate number system (ANS is the hypothesized cognitive mechanism that allows adults, infants, and animals to enumerate large sets of items approximately. Researchers usually assess the ANS by having subjects compare two sets and indicate which is larger. Accuracy or Weber fraction is taken as an index of the acuity of the system. However, as Clayton et al., (2015 have highlighted, the stimulus parameters used when assessing the ANS vary widely. In particular, the numerical ratio between the pairs, and the way in which non-numerical features are varied often differ radically between studies. Recently, Clayton et al. (2015 found that accuracy measures derived from two commonly used stimulus sets are not significantly correlated. They argue that a lack of inter-test reliability threatens the validity of the ANS construct. Here we apply a recently developed modeling technique to the same data set. The model, by explicitly accounting for the effect of numerical ratio and non-numerical features, produces dependent measures that are less perturbed by stimulus protocol. Contrary to their conclusion we find a significant correlation in Weber fraction across the two stimulus sets. Nevertheless, in agreement with Clayton et al., we find that different protocols do indeed induce differences in numerical acuity and the degree of influence of non-numerical stimulus features. These findings highlight the need for a systematic investigation of how protocol idiosyncrasies affect ANS assessments.

  8. Significant Inter-Test Reliability across Approximate Number System Assessments. (United States)

    DeWind, Nicholas K; Brannon, Elizabeth M


    The approximate number system (ANS) is the hypothesized cognitive mechanism that allows adults, infants, and animals to enumerate large sets of items approximately. Researchers usually assess the ANS by having subjects compare two sets and indicate which is larger. Accuracy or Weber fraction is taken as an index of the acuity of the system. However, as Clayton et al. (2015) have highlighted, the stimulus parameters used when assessing the ANS vary widely. In particular, the numerical ratio between the pairs, and the way in which non-numerical features are varied often differ radically between studies. Recently, Clayton et al. (2015) found that accuracy measures derived from two commonly used stimulus sets are not significantly correlated. They argue that a lack of inter-test reliability threatens the validity of the ANS construct. Here we apply a recently developed modeling technique to the same data set. The model, by explicitly accounting for the effect of numerical ratio and non-numerical features, produces dependent measures that are less perturbed by stimulus protocol. Contrary to their conclusion we find a significant correlation in Weber fraction across the two stimulus sets. Nevertheless, in agreement with Clayton et al. (2015) we find that different protocols do indeed induce differences in numerical acuity and the degree of influence of non-numerical stimulus features. These findings highlight the need for a systematic investigation of how protocol idiosyncrasies affect ANS assessments.

  9. Smoke-free policy implementation: theoretical and practical considerations. (United States)

    Fallin, Amanda; Goodin, Amie; Rayens, Mary Kay; Morris, Sarah; Hahn, Ellen J


    Secondhand smoke exposure is a major public health issue, increasing the risk of cardiovascular and respiratory diseases and cancer. Although best practices for adopting smoke-free policy are well understood, there is limited research on the effective implementation of smoke-free policy. This article presents theoretical and practical considerations for smoke-free policy implementation in three Kentucky communities guided by the Institutional Analysis and Development (IAD) Framework. Although both Danville and Lexington-Fayette County, Kentucky have comprehensive smoke-free policies, Danville had more effective implementation, as well as better outcomes. Further study is needed to understand the critical elements of smoke-free policy implementation and their association with population outcomes. The IAD is a promising model to guide the study of both policy adoption and implementation. © The Author(s) 2015 Reprints and permissions:

  10. Extra cogeneration step seen boosting output 20%

    Energy Technology Data Exchange (ETDEWEB)

    Burton, P.


    Cogenerators can now buy a prototype 6.5 MW, pre-packaged cogeneration system that incorporates an added step to its cycle to reduce fuel use by 21%. Larger, custom-designed systems will be on the market in 1985. Fayette Manufacturing Co. will offer the Kalina Cycle system at a discount price of $8.2 million (1200/kW) until the systems are competitive with conventional units. The system varies from conventional cogeneration systems by adding a distillation step, which permits the use of two fluids for the turbine steam and operates at a higher thermodynamic efficiency, with boiling occuring at high temperature and low pressure. Although theoretically correct, DOE will withhold judgment on the system's efficiency until the first installation is operating.


    Energy Technology Data Exchange (ETDEWEB)

    WM. Stanton McDonald; Christopher M. Long


    This report highlights the drilling of two shallow oil wells in Fayette County, Texas. The operator of these two wells was Stanton Mineral Development, Inc. The aim of this project was to successfully complete the two (2) wells, emphasizing tight oversight of the technological aspects, neglect of which are the primary causes of failure in this mature producing region as well as unnecessarily expensive wells. Discussions contained here within are not limited to just the execution of the project itself, but a historical and technical analysis which forms a basis for the decisions made both during drilling and completion. Additionally, there is substantial dialogue covering the financial benefits associated with the findings of this project.

  12. Designing a clinical audit tool to measure processes of pregnancy care

    Directory of Open Access Journals (Sweden)

    Wallace EM


    Full Text Available Suzanne V Sinni1, Wendy M Cross2, Euan M Wallace1,31Department of Obstetrics and Gynaecology, Monash University and Southern Health, Monash Medical Centre, Clayton, Victoria, 2School of Nursing and Midwifery, Monash University, Clayton, Victoria, 3The Ritchie Centre, Monash Institute of Medical Research, Monash University, Clayton, Victoria, AustraliaAbstract: This paper reports the development of a clinical audit tool as part of a larger project to evaluate a new maternity service, underpinned by a patient safety framework.Aim: The aim of this work is to describe the development of a clinical audit tool that measures the process of pregnancy care, and its application.Background: There are many reports about outcomes of healthcare provision, however there are limited studies examining the process of care. There is also limited evidence linking clinical audit with improvements in care delivery. Pregnancy care was chosen because there are well defined and agreed clinical standards against which to measure the delivery of pregnancy care. A clinical audit using these standards addresses both gaps in the literature.Methods: Standard methodological processes were used to develop the audit tool. Literature informed the processes. Data were collected in 2009–2010 using the tool described in the paper. Reliability testing was completed in September 2011.Results: An audit tool to measure pregnancy care was developed and applied to 354 health records to enable analysis of adherence to organizational expectations of care. Reliability testing of the tool achieved an overall kappa of 0.896.Conclusion: Developing an audit tool based on processes described in the literature is labor intensive and resource dependent, however it results in a robust, reliable, valid tool that can be used in diverse maternity services. Stakeholder participation from the outset ensures ongoing engagement for the duration of a clinically based project spanning several years

  13. The United States Air Force Academy: a Bibliography 1972-1982 (United States)


    Air Force Base, Fla.: Civil and Environmental Engineering Development Office, 1978. (TH 7413 .E22) 139 Marley , Frederick H. A proposal for the...1978-80 Rep. David C. Treen 1975-76 Mr. Churchill T. Williams 1973-75 Rep. Bob Wilson 1977-78 Rep. Charles H. Wilson 1972-73 Dr. Sheila E. Windall 1978...575 Mark, Hans M., 560 ivins, Molly, 466 Markey, J. H., 278 James, D. Clayton, 576 Marley , Frederick H., 139 Janson, Donald, 467 Martin, Ben, 656

  14. Design and development of an automotive propulsion system utilizing a Rankine cycle engine (water based fluid). Final report

    Energy Technology Data Exchange (ETDEWEB)

    Demler, R.L.


    Under EPA and ERDA sponsorship, SES successfully designed, fabricated and tested the first federally sponsored steam powered automobile. The automobile - referred to as the simulator - is a 1975 Dodge Monaco standard size passenger car with the SES preprototype Rankine cycle automotive propulsion system mounted in the engine compartment. In the latter half of 1975, the simulator successfully underwent test operations at the facilities of SES in Watertown, Massachusetts and demonstrated emission levels below those of the stringent federally established automotive requirements originally set for implementation by 1976. The demonstration was accomplished during testing over the Federal Driving Cycle on a Clayton chassis dynamometer. The design and performance of the vehicle are described.

  15. Disruptiv innovasjon i norsk næringsliv : En kvalitativ studie basert på 10 norske bedriftslederes erfaringer med disruptiv innovasjon


    Polden, Monica Myklebust; Røisvold, Hans Marius


    Temaet for denne avhandlingen er disruptiv innovasjon som Clayton M. Christensen først introduserte i artikkelen Disruptive technologies: Catching the wave i(1995)og senere i boken The Innovator’s Dilemma i 1997. Disruptive innovasjoner handler om produkter eller tjenester som oppstår i markedet og endrer konkurransereglene. Dette skjer ved at det oppstås nye markeder (new market disruptions) eller ved at det blir produsert lignende produkter eller tjenester med gjerne dårligere kvalitet og f...

  16. Complement Receptor 1 Is a Sialic Acid-Independent Erythrocyte Receptor of Plasmodium falciparum (United States)


    Investigaciones Científicas y Servicios de Alta Tecnología-AIP (INDICASAT- AIP), Ciudad del Saber, Clayton, Panamá, 4 Division of Malaria Vaccine Development, the...Hospital Robert Debré, Reims, France ). An IgG1 irrelevant monoclonal (R&D Systems, Minneapolis, MN, USA) and anti-CD55 monoclonal (clone NaM16-4D3, IgG1...providing the 3D7 strain, and to Dr. Jacques Cohen of the University of Reims, France , for the gift of monoclonal antibody J3B11. We thank Dr. Fujuki

  17. Crossing Borders: An Interdisciplinary Course in the "Enlightenment"

    Directory of Open Access Journals (Sweden)

    Carol White


    Full Text Available In this essay, we present a twofold version of the first team-taught course on the eighteenth century designed by faculty at Clayton State University who plan to develop and teach this course again in the near future. We hope that our explanation of the original course and our projected future version of the course will be useful to scholars who teach in the eighteenth century, as well as to specialists in other historical periods who wish to plan revisions of courses to make them more reflective of current scholarship in gender studies. Authors taught in this course include Benjamin Franklin, Voltaire, Denis Diderot, Helen Maria Williams, and others.

  18. Prevalence of Helicobacter Pylori in Gastric Fluid in the Surgical Patient (United States)


    Isolation of H. pylori from human faeces . Lancet, 340, 1194-5. Tomb, J.F., White, O., Kerlavage, A.R., Clayton, R.A., Sutton, G.G., Fleischmann, R.D... human gastric mucosa. It is well established as a primary factor in peptic ulcer disease and has been implicated in the pathogenesis of gastric...century in animals and later at the turn of the 20th century in humans , (Dubois, 1995). At the onset of the 20th century, stress and dietary factors

  19. The Leadership Philosophy Model (United States)


    34 leadership philosophy"? One writer states that it is a "distillation of experience and theory , arrived at through a long and somewhat tenuous process of... LEADERSHIP PHILOSOPHY MfODEL .11.9BY .IELJTEN 1NT CO)LONEL CLAYTON E. MELTO.; DIST-. jUTION STATEMIS.T A’ Approved for publiC relea~se; distributicrn...CATALOG NUMBER 4 TITLE (-d Subtitle) T YPE OF REPORT & PERIOD COvERE3 The Leadership Philosophy Model Study Project 6. PERFORMING ORG. REPORT N,.MBER 7

  20. Confronting empty spaces: between interpretation and experience in "The Turn of the Screw" by Henry James

    Directory of Open Access Journals (Sweden)

    Antonia Spinelli


    Full Text Available The Turn of the Screw by Henry James has inspired the most various critical debates for over a century. What is hidden in the folds of the story? What kind of impact does it have on the reader? Like a borderless nebula who attracts and reflects light from other stars, this novella is permeated by a vide fascinant, by a chaotic and disturbing matter “such stuff as dreams are made”. This feeling of absence and uncertainty, that characterizes the story, developed trough the contribution of readers and critics and it found a further still precious echo in The Innocents, a film directed by Jack Clayton in 1961.

  1. Nanocompósitos de poliamida 6 e argila organofílica: estudo da cristalinidade e propriedades mecânicas Nanocomposites of polyamide 6 and organoclay: crystallinity and study of mechanical properties

    Directory of Open Access Journals (Sweden)

    Marcelo F. L. de Oliveira


    Full Text Available Nanocompósitos de poliamida 6 e argila organofílica claytone 40 foram preparados por intercalação por fusão, utilizando misturador de câmara interna equipado com rotores do tipo Roller. A adição de teores crescentes de claytone 40 na matriz de PA6 foi avaliada quanto ao grau de dispersão, cristalinidade, propriedades térmicas e as propriedades mecânicas. As composições obtidas foram caracterizadas por difração de raios X (DRX, calorimetria diferencial de varredura (DSC, microscopia eletrônica de varredura (MEV e propriedades mecânicas. Os difratogramas e as micrografias sugeriram a ocorrência de formação de estruturas parcialmente esfoliadas e/ ou intercaladas, fato que foi associado com o aumento nos valores de tensão e o módulo elástico. A comparação entre os resultados de DSC e DRX das misturas revelaram alterações estruturais na cristalinidade em relação à PA6 correlacionando a cristalinidade à variação nas propriedades mecânicas.Nanocomposites of polyamide 6 and Claytone 40 organoclay were prepared with the melt intercalation technique using an internal mixer chamber coupled with roller type rotors. The addition of increasing amounts of Claytone 40 into the PA6 matrix was evaluated for the degree of dispersion, crystallinity, thermal and mechanical properties. The compositions were characterized with X-ray diffraction (XRD, differential scanning calorimetry (DSC, scanning electron microscopy (SEM and mechanical properties. The diffraction patterns and microscope images suggest the formation of partially exfoliated or intercalated structures, which was associated with an increase in stress values and elastic modulus. The comparison of DSC and XRD results from the mixtures revealed changes in the behavior of crystalline structures, thus indicating that the PA6 crystallinity is correlated with the mechanical properties.

  2. Dependence between Croatian and European stock markets – A copula GARCH approach

    Directory of Open Access Journals (Sweden)

    Silvo Dajčman


    Full Text Available The objective of this paper is to analyze dependence structure between the returns of Croatian and five European stock markets (Austrian, French, German, Italian, and the U.K.'s. We propose a copula GARCH approach, where the return series are modeled as univariate GARCH processes and the dependence structure between the return series is defined by a copula function. Four different copulas are fitted - a constant and conditional normal and symmetric Joe-Clayton (SJC copulas - and estimated by a semi-parametric method. We found that the time-varying normal copula yields the best fit for CROBEX-CAC40, CROBEX-DAX, and CROBEX-FTSE-MIB stock indices pairs, while the time-varying SJC copula is the best fit for CROBEX-ATX and CROBEX-FTSE100. Further, we found that the probability of simultaneous extreme positive and negative returns in Croatian and other European stock markets can increase to 0.77 during turbulent times. The lower and upper tail dependence dynamics between Croatian and other European stock markets is similar in pattern, differing only in scale. The basic conclusion of the research is that the dependence between the stock markets of Croatia and five major European stock markets is dynamic and can be properly captured by either a dynamic normal or symmetrized Joe-Clayton copula GARCH models.


    International Nuclear Information System (INIS)

    Puigh, R.J.


    In 1974, a small innocuous document was submitted to the American Nuclear Society's Criticality Safety Division for publication that would have lasting impacts on this nuclear field The author was Duane Clayton, manager of the Battelle Pacific Northwest National Laboratory's Critical Mass Lab, the world's preeminent reactor critical experimenter with plutonium solutions. The document was entitled, 'Anomalies of Criticality'. 'Anomalies...' was a compilation of more than thirty separate and distinct examples of departures from what might be commonly expected in the field of nuclear criticality. Mr. Clayton's publication was the derivative of more than ten thousand experiments and countless analytical studies conducted world-wide on every conceivable reactor system imaginable: from fissile bearing solutions to solids, blocks to arrays of fuel rods, low-enriched uranium oxide systems to pure plutonium and highly enriched uranium systems. After publication, the document was commonly used within the nuclear fuel cycle and reactor community to train potential criticality/reactor analysts, experimenters and fuel handlers on important things for consideration when designing systems with critically 'safe' parameters in mind The purpose of this paper is to re-introduce 'Anomalies of Criticality' to the current Criticality Safety community and to add new 'anomalies' to the existing compendium. By so doing, it is the authors' hope that a new generation of nuclear workers and criticality engineers will benefit from its content and might continue to build upon this work in support of the nuclear renaissance that is about to occur

  4. Looking for episodic memory in animals and young children: prospects for a new minimalism. (United States)

    Clayton, Nicola S; Russell, James


    Because animals and young children cannot be interrogated about their experiences it is difficult to conduct research into their episodic memories. The approach to this issue adopted by Clayton and Dickinson [Clayton, N. S., & Dickinson, A. (1998). Episodic-like memory during cache recovery by scrub jays. Nature, 395, 272-274] was to take a conceptually minimalist definition of episodic memory, in terms of integrating information about what was done where and when [Tulving, E. (1972). Episodic and semantic memory. In E. Tulving, & W. Donaldson (Eds.), Organisation of memory (pp. 381-403). New York: Academic Press], and to refer to such memories as 'episodic-like'. Some claim, however, that because animals supposedly lack the conceptual abilities necessary for episodic recall one should properly call these memories 'semantic'. We address this debate with a novel approach to episodic memory, which is minimalist insofar as it focuses on the non-conceptual content of a re-experienced situation. It rests on Kantian assumptions about the necessary 'perspectival' features of any objective experience or re-experience. We show how adopting this perspectival approach can render an episodic interpretation of the animal data more plausible and can also reveal patterns in the mosaic of developmental evidence for episodic memory in humans.

  5. Specious causal attributions in the social sciences: the reformulated stepping-stone theory of heroin use as exemplar. (United States)

    Baumrind, D


    The claims based on causal models employing either statistical or experimental controls are examined and found to be excessive when applied to social or behavioral science data. An exemplary case, in which strong causal claims are made on the basis of a weak version of the regularity model of cause, is critiqued. O'Donnell and Clayton claim that in order to establish that marijuana use is a cause of heroin use (their "reformulated stepping-stone" hypothesis), it is necessary and sufficient to demonstrate that marijuana use precedes heroin use and that the statistically significant association between the two does not vanish when the effects of other variables deemed to be prior to both of them are removed. I argue that O'Donnell and Clayton's version of the regularity model is not sufficient to establish cause and that the planning of social interventions both presumes and requires a generative rather than a regularity causal model. Causal modeling using statistical controls is of value when it compels the investigator to make explicit and to justify a causal explanation but not when it is offered as a substitute for a generative analysis of causal connection.

  6. Relationship of Temperature and Light Ring Formation at Subarctic Treeline and Implications for Climate Reconstruction (United States)

    Yamaguchi, David K.; Filion, Louise; Savage, Melissa


    During the past 8 centuries, light rings (LRs) have occasionally formed in black spruce ( Picea mariana) at treeline near Bush Lake, northern Quebec (L. Filion, S. Payette, L. Gauthier, and Y. Boutin, 1986, Quaternary Research 26, 272-279; A. Delwaide, L. Filion, and S. Fayette, 1991, Canadian Journal of Forest Research 21, 1828-1832). New analyses of climate data compiled during the period of overlapping tree-ring and instrumental records show that years of LR formation at Bush Lake have unusually cool May, June, August, and September temperatures. The analyses also show that August-September temperatures strongly correlate with May-July temperatures. Thus, late spring and entire growing-season temperatures influence LR formation at subarctic treeline. LRs formed in at least 5% of the trees at Bush Lake when May-September mean temperatures at Inukjuak fell below 4.2°C and August-September mean temperatures fell below 6.7°C. These threshold temperature/LR relationships can be used to infer limiting summer temperatures during the period preceding instrumental records. For example, the LR record suggests that May-September temperatures at northern Quebec treeline dropped below 4.2°C in A.D. 1601 after a major volcanic eruption of unknown source. Visual assessments of LR occurrence provide a new approach for extracting quantitative paleoclimatic information from tree rings.

  7. Characteristics of peak streamflows and extent of inundation in areas of West Virginia and southwestern Virginia affected by flooding, June 2016 (United States)

    Austin, Samuel H.; Watson, Kara M.; Lotspeich, R. Russell; Cauller, Stephen J.; White , Jeremy S.; Wicklein, Shaun M.


    Heavy rainfall occurred across central and southern West Virginia in June 2016 as a result of repeated rounds of torrential thunderstorms. The storms caused major flooding and flash flooding in central and southern West Virginia with Kanawha, Fayette, Nicholas, and Greenbrier Counties among the hardest hit. Over the duration of the storms, from 8 to 9.37 inches of rain was reported in areas in Greenbrier County. Peak streamflows were the highest on record at 7 locations, and streamflows at 18 locations ranked in the top five for the period of record at U.S. Geological Survey streamflow-gaging stations used in this study. Following the storms, U.S. Geological Survey hydrographers identified and documented 422 high-water marks in West Virginia, noting location and height of the water above land surface. Many of these high-water marks were used to create flood-inundation maps for selected communities of West Virginia that experienced flooding in June 2016. Digital datasets of the inundation areas, mapping boundaries, and water depth rasters are available online.

  8. Adultère et romantisme

    Directory of Open Access Journals (Sweden)

    Annik Houel


    Full Text Available En ce début de XIXème siècle, le combat que mène George Sand pour le droit des femmes à l’amour s’inscrit dans la tradition d’une contestation - qu’on peut qualifier de féministe - qui porte essentiellement sur les conditions du mariage, le plus souvent arrangé. Le leitmotiv de l’amour, qui traverse les oeuvres de la plupart des femmes qui l’ont précédée en littérature manifeste leur opposition au mariage tel qu’il leur est imposé, et l’adultère symbolise leur rêve : ainsi en va-t-il, dès le Moyen-Âge, pour Marie de France, Christine de Pisan, Marguerite de Navarre même, et bien sûr pour Madame de La Fayette avec La Princesse de Clèves qui incarne le clivage psychique entre corps et esprit auquel les femmes sont alors acculées.

  9. Practical assessment of magnetic methods for corrosion detection in an adjacent precast, prestressed concrete box-beam bridge (United States)

    Fernandes, Bertrand; Titus, Michael; Nims, Douglas Karl; Ghorbanpoor, Al; Devabhaktuni, Vijay Kumar


    Magnetic methods are progressing in the detection of corrosion in prestressing strands in adjacent precast, prestressed concrete box-beam bridges. This study is the first field trial of magnetic strand defect detection systems on an adjacent box-beam bridge. A bridge in Fayette County, Ohio, which was scheduled for demolition, was inspected. Damage to prestressed box-beams is often due to corrosion of the prestressing strands. The corroded strands show discontinuities and a reduced cross-sectional area. These changes, due to corrosion, are reflected in the magnetic signatures of the prestressing steel. Corrosion in the prestressing steel was detected using two magnetic methods, namely the 'magnetic flux leakage' (MFL) and the 'induced magnetic field'. The purpose of these tests was to demonstrate the ability of the magnetic methods to detect hidden corrosion in box-beams in the field and tackle the logistic problem of inspecting box-beams from the bottom. The inspections were validated by dissecting the bottom of the box-beams after the inspections. The results showed that the MFL method can detect hidden corrosion and strand breaks. Both magnetic field methods were also able to estimate corrosion by detecting the effective cross-sectional area of the strand in sections of the beams. Thus, it was shown that the magnetic methods can be used to predict hidden corrosion in prestressing strands of box-beams.

  10. Biomass power for rural development. Technical progress report, October 1--December 31, 1997

    Energy Technology Data Exchange (ETDEWEB)

    Neuhauser, E.


    The focus of the DOE/USDA sponsored biomass power for rural development project is to develop commercial energy crops for power generation by the year 2000. The New York based Salix Consortium project is a multi-partner endeavor, implemented in three stages. Phase-1, Final Design and Project Development, will conclude with the preparation of construction and/or operating permits, feedstock production plans, and contracts ready for signature. Field trials of willow (Salix) have been initiated at several locations in New York (Tully, Lockport, King Ferry, La Fayette, Massena, and Himrod) and co-firing tests are underway at Greenidge Station (NYSEG) and Dunkirk Station (NMPC). Phase-2 of the project will focus on scale-up of willow crop acreage, construction of co-firing facilities at Dunkirk Station (NMPC), and final modifications for Greenidge Station. Cofiring willow is also under consideration for GPU`s Seward Station where testing is underway. There will be an evaluation of the energy crop as part of the gasification trials occurring at BED`s McNeill Power Station. Phase-3 will represent fullscale commercialization of the energy crop and power generation on a sustainable basis. During the fourth quarter of 1997 the Consortium submitted a Phase-2 proposal. A few of the other more important milestones are outlined below. The first quarter of 1998 will be dominated by pre-planting activity in the spring.

  11. A model of rotationally-sampled wind turbulence for predicting fatigue loads in wind turbines (United States)

    Spera, David A.


    Empirical equations are presented with which to model rotationally-sampled (R-S) turbulence for input to structural-dynamic computer codes and the calculation of wind turbine fatigue loads. These equations are derived from R-S turbulence data which were measured at the vertical-plane array in Clayton, New Mexico. For validation, the equations are applied to the calculation of cyclic flapwise blade loads for the NASA/DOE Mod-2 2.5-MW experimental HAWT's (horizontal-axis wind turbines), and the results compared to measured cyclic loads. Good correlation is achieved, indicating that the R-S turbulence model developed in this study contains the characteristics of the wind which produce many of the fatigue loads sustained by wind turbines. Empirical factors are included which permit the prediction of load levels at specified percentiles of occurrence, which is required for the generation of fatigue load spectra and the prediction of the fatigue lifetime of structures.

  12. An energy absorbing far-field boundary condition for the elastic wave equation

    Energy Technology Data Exchange (ETDEWEB)

    Petersson, N A; Sjogreen, B


    The authors present an energy absorbing non-reflecting boundary condition of Clayton-Engquist type for the elastic wave equation together with a discretization which is stable for any ratio of compressional to shear wave speed. They prove stability for a second order accurate finite-difference discretization of the elastic wave equation in three space dimensions together with a discretization of the proposed non-reflecting boundary condition. The stability proof is based on a discrete energy estimate and is valid for heterogeneous materials. The proof includes all six boundaries of the computational domain where special discretizations are needed at the edges and corners. The stability proof holds also when a free surface boundary condition is imposed on some sides of the computational domain.

  13. Heterogenous networks and services

    DEFF Research Database (Denmark)

    Tan, Su-En


    representations of strategy, will then help to determine the success or failure of the technology. This is shown typically in the case of WiFi. WiFi is a wireless technology that addressed a new market, but was soon adopted as a complement by mobile operators into their suite of services. However, the future....... Incremental technological changes are characterised by small changes that are linked to the previous generation of technology and are seen to be advancements of that technology. Radical technological changes, on the other hand, are characterised by a new innovative technology that is different from...... the existing generation of technology and presents new technological performance breakthroughs. It is difficult to predict which radical technologies or innovations will result in a market disruption early on in their life cycles. Based on Clayton Christensen’s (Christensen 1997) definition of a disruptive...

  14. Point-of-service nerve conduction studies: an example of industry-driven disruptive innovation in health care. (United States)

    Lesser, Eugene A; Starr, Jennifer; Kong, Xuan; Megerian, J Thomas; Gozani, Shai N


    Nerve conduction studies (NCS) and needle electromyography are useful and established diagnostic procedures for evaluating patients with signs and symptoms of neuromuscular disease. Although technological advances have occurred since the introduction of commercial electromyography instrumentation in the 1950s, most improvements have been evolutionary and were designed to benefit traditional users--neurologists and physiatrists specializing in electromyography. In the past seven years, instruments have been introduced that automate NCS and thereby enable a broader group of physicians, including internists and orthopedic surgeons, to perform these studies and utilize electromyographic data in the care of their patients. Automated NCS devices are an example of what Clayton Christensen terms a "disruptive innovation." In this article, automated NCS is contrasted with traditional electromyography, and the challenges and opposition to its widespread adoption are explored.

  15. Mineralogical and geochemical controls on the release of trace elements from slag produced by base- and precious-metal smelting at abandoned mine sites (United States)

    Piatak, N.M.; Seal, R.R.; Hammarstrom, J.M.


    Slag collected from smelter sites associated with historic base-metal mines contains elevated concentrations of trace elements such as Cu, Zn and Pb. Weathering of slag piles, many of which were deposited along stream banks, potentially may release these trace elements into the environment. Slags were sampled from the Ely and Elizabeth mines in the Vermont copper belt, from the copper Basin mining district at Ducktown, Tennessee and from the Clayton silver mine in the Bayhorse mining district, Idaho, in the USA. Primary phases in the slags include: olivine-group minerals, glass, spinels, sulfide minerals and native metals for Vermont samples; glass, sulfide minerals and native metals for the Ducktown sample; and olivine-group minerals, clinopyroxenes, spinels, sulfide minerals, native metals and other unidentified metallic compounds for Clayton slag. Olivine-group minerals and pyroxenes are dominantly fayalitic and hedenbergitic in composition, respectively and contain up to 1.25 wt.% ZnO. Spinel minerals range between magnetite and hercynite in composition and contain Zn (up to 2.07 wt.% ZnO), Ti (up to 4.25 wt.% TiO2) and Cr (up to 1.39 wt.% Cr2O3). Cobalt, Ni, Cu, As, Ag, Sb and Pb occur in the glass phase, sulfides, metallic phases and unidentified metallic compounds. Bulk slag trace-element chemistry shows that the metals of the Vermont and Tennessee slags are dominated by Cu (1900-13,500 mg/kg) and Zn (2310-10,200 mg/kg), whereas the Clayton slag is dominated by Pb (63,000 mg/kg), Zn (19,700 mg/kg), Cu (7550 mg/kg), As (555 mg/kg), Sn (363 mg/kg) and Ag (200 mg/kg). Laboratory-based leach tests indicate metals can be released under simulated natural conditions. Leachates from most slags were found to contain elevated concentrations of Cu and Zn (up to 1800 and 470 ??g/l, respectively), well in excess of the acute toxicity guidelines for aquatic life. For the Idaho slag, the concentration of Pb in the leachate (11,000 ??g/l) is also in excess of the acute

  16. Review: La expansión del conocimiento en abierto: Los Moocs. Vázquez, E.; López-Meneses, E. y Sarasola, J.L. (2013. Barcelona: Octaedro, 119 pp.

    Directory of Open Access Journals (Sweden)

    David Cobos Sanchiz


    Full Text Available When Professor Clayton Christensen introduced the concept of disruptive innovation, he referred to it as the one produced with goods or services that, originally born as something almost residual, quickly become leader in their field. Well, according to this definition, MOOCs (Massive Open Online Course, as Lluís Anglada has already stated, are a clear example of disruption for several reasons: because of their cost, because they are based on new insights into the psychology of learning, and because they are adapted to the new social needs towards education.

  17. Coupling factors, visual rhythms, and synchronization ratios

    Directory of Open Access Journals (Sweden)

    Udo Will


    Full Text Available The inter-group entrainment study by Lucas, Clayton, and Leante (2011 is an interesting research report that advances studies in both empirical ethnomusicology and entrainment research in several ways, and provides an important addition to the much needed empirical case studies on musical entrainment. I submit that the authors’ analysis of an instant of resistance to entrainment is a key demonstration of the complementarity of analytical and ethnographic approaches in entrainment research. Further, I suggest that the evidence for the influence of visual information on entrainment supports the idea that there are two types of visuo-temporal information, each with different influence on the entrainment process, those derived from static and those from moving visual objects. As a final point, I argue that if we take into consideration the possibility of higher-order synchronization, some of the authors’ interpretations would need modification.

  18. Assessment of near-surface dissolution at and near the Waste Isolation Pilot Plant (WIPP), southeastern New Mexico

    International Nuclear Information System (INIS)

    Bachman, G.O.


    The area at and near the WIPP site was examined for evidence of karst development on the geomorphic surface encompassing the site. Certain surficial depressions of initial concern were identified as blowouts in sand dune fields (shallow features unrelated to karstification). An ancient stream system active more than 500,000 yr ago contained more water than any system since. During that time (Gatuna, Middle Pleistocene), many karst features such as Clayton Basin and Nash Draw began to form in the region. Halite was probably dissolved from parts of the Rustler Formation at that time. Dissolution of halite and gypsum from intervals encountered in Borehole WIPP-33 west of the WIPP site occurred during later Pleistocene time (i.e., <450,000 yr ago). However, there is no evidence of active near-surface dissolution within a belt to the east of WIPP-33 in the vicinity of the WIPP shaft. 26 refs., 11 figs., 1 tab

  19. Thermal Conductivity of Carbon Nanoreinforced Epoxy Composites

    Directory of Open Access Journals (Sweden)

    C. Kostagiannakopoulou


    Full Text Available The present study attempts to investigate the influence of multiwalled carbon nanotubes (MWCNTs and graphite nanoplatelets (GNPs on thermal conductivity (TC of nanoreinforced polymers and nanomodified carbon fiber epoxy composites (CFRPs. Loading levels from 1 to 3% wt. of MWCNTs and from 1 to 15% wt. of GNPs were used. The results indicate that TC of nanofilled epoxy composites increased with the increase of GNP content. Quantitatively, 176% and 48% increase of TC were achieved in nanoreinforced polymers and nanomodified CFRPs, respectively, with the addition of 15% wt. GNPs into the epoxy matrix. Finally, micromechanical models were applied in order to predict analytically the TC of polymers and CFRPs. Lewis-Nielsen model with optimized parameters provides results very close to the experimental ones in the case of polymers. As far as the composites are concerned, the Hashin and Clayton models proved to be sufficiently accurate for the prediction at lower filler contents.

  20. The Red Atrapa Sismos (Quake Catcher Network in Mexico): assessing performance during large and damaging earthquakes. (United States)

    Dominguez, Luis A.; Yildirim, Battalgazi; Husker, Allen L.; Cochran, Elizabeth S.; Christensen, Carl; Cruz-Atienza, Victor M.


    The Quake‐Catcher Network (QCN) is an expanding seismic array made possible by thousands of participants who volunteered time and resources from their computers to record seismic data using low‐cost accelerometers (; last accessed December 2014). Sensors based on Micro‐Electromechanical Systems (MEMS) technology have rapidly improved over the last few years due to the demand of the private sector (e.g., automobiles, cell phones, and laptops). For strong‐motion applications, low‐cost MEMS accelerometers have promising features due to an increasing resolution and near‐linear phase and amplitude response (Cochran, Lawrence, Christensen, and Jakka, 2009; Clayton et al., 2011; Evans et al., 2014).

  1. Volatile organometallic and semiconductor materials

    International Nuclear Information System (INIS)

    Dickson, R.S.


    This article reports on a project concerned with the metal organic chemical vapour deposition (MOCVD) of mercury-cadmium telluride (MCT) undertaken by a research consortium based in the Clayton area involving Monash University Chemistry Department, Telecom Research Laboratories, and CSIRO Division of Material Sciences and Technology. An M.R. Semicon 226 MOCVD reactor, operating near atmospheric presure with hydrogen carrier gas has been used. Most applications of MCT are direct consequence of its responsiveness to radiation in infrared region spectrum. The main aims of the project were to prepare and assess a range of volatile organometallics that might find use as a dopant sources for MCT, to prepare and study the properties of a range of different lanthanide complexes for MOCVD applications and to fully characterize the semiconductor wafers after growth. 19 refs., 3 figs

  2. The microspectroscopy beamline for the Australian synchrotron project

    International Nuclear Information System (INIS)

    Boldeman, J.W.; Ryan, C.; Cohen, D.D.


    A new multi-million dollar synchrotron facility is currently being built in Clayton, Victoria. This is a 3GeV electron machine, it will be a world class machine and contain state of the art beamline facilities for both Australian and overseas scientists. It is due for completion in mid-2007. This specialised beamline will provide sub-micron spatial resolution with the highest flux possible. It will combine 2D mapping with micro X-ray fluorescence (μ-XRF), micro X-ray absorption near edge spectroscopy (μ-XANES) and micro X-ray absorption fine structure spectroscopy (μ-XAFS) for elemental and chemical analysis to solve scientific problems that can only be understood using X-ray beams with sub-micron resolutions. In this paper we describe some key beamline components and give details about their performance specifications. 7 refs., 4 figs.; 1 tab

  3. Assessment of near-surface dissolution at and near the Waste Isolation Pilot Plant (WIPP), southeastern New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Bachman, G.O.


    The area at and near the WIPP site was examined for evidence of karst development on the geomorphic surface encompassing the site. Certain surficial depressions of initial concern were identified as blowouts in sand dune fields (shallow features unrelated to karstification). An ancient stream system active more than 500,000 yr ago contained more water than any system since. During that time (Gatuna, Middle Pleistocene), many karst features such as Clayton Basin and Nash Draw began to form in the region. Halite was probably dissolved from parts of the Rustler Formation at that time. Dissolution of halite and gypsum from intervals encountered in Borehole WIPP-33 west of the WIPP site occurred during later Pleistocene time (i.e., <450,000 yr ago). However, there is no evidence of active near-surface dissolution within a belt to the east of WIPP-33 in the vicinity of the WIPP shaft. 26 refs., 11 figs., 1 tab.

  4. Oxygen isotopic heterogeneities, their petrological correlations, and implications for melt origins of chondrules in unequilibrated ordinary chondrites (United States)

    Gooding, J. L.; Mayeda, T. K.; Clayton, R. N.; Fukuoka, T.


    Clayton et al. (1976, 1982) established that equilibrated ordinary chondrites (EOC's) can be divided into the H- and L-groups on the basis of their oxygen isotopic composition. The present investigation is concerned with new oxygen isotopic analyses of petrologically well-characterized individual chondrules from the unequilibrated chondrites Dhajala (H3,4), Hallingeberg (L3), and Semarkona (LL3). A study is conducted regarding the implications of isotopic/petrologial correlations for the origin of chondrules in ordinary chondrites. It is found that the oxygen isotopic heterogeneities among chondrules are reminiscent of the bulk elemental and phase compositional heterogeneities among the same and other chondrules as reported by Gooding et al. (1979, 1980). It is concluded that chondrules formed possibly as a result of the melting of preexisting materials which were both chemically and isotopically heterogeneous.

  5. The effect of catastrophic collisional fragmentation and diffuse medium accretion on a computational interstellar dust system

    International Nuclear Information System (INIS)

    Liffman, K.


    The effects of catastrophic collisional fragmentation and diffuse medium accretion on a the interstellar dust system are computed using a Monte Carlo computer model. The Monte Carlo code has as its basis an analytic solution of the bulk chemical evolution of a two-phase interstellar medium, described by Liffman and Clayton (1989). The model is subjected to numerous different interstellar processes as it transfers from one interstellar phase to another. Collisional fragmentation was found to be the dominant physical process that shapes the size spectrum of interstellar dust. It was found that, in the diffuse cloud phase, 90 percent of the refractory material is locked up in the dust grains, primarily due to accretion in the molecular medium. This result is consistent with the observed depletions of silicon. Depletions were found to be affected only slightly by diffuse cloud accretion. 42 refs

  6. 19th International Conference on Interactive Collaborative Learning

    CERN Document Server

    Guralnick, David; Uhomoibhi, James


    This book presents the proceedings of the 19th International Conference on Interactive Collaborative Learning, held 21-23 September 2016 at Clayton Hotel in Belfast, UK. We are currently witnessing a significant transformation in the development of education. The impact of globalisation on all areas of human life, the exponential acceleration of developments in both technology and the global markets, and the growing need for flexibility and agility are essential and challenging elements of this process that have to be addressed in general, but especially in the context of engineering education. To face these topical and very real challenges, higher education is called upon to find innovative responses. Since being founded in 1998, this conference has consistently been devoted to finding new approaches to learning, with a focus on collaborative learning. Today the ICL conferences have established themselves as a vital forum for the exchange of information on key trends and findings, and of practical lessons le...

  7. Fecal examination of the equids of Tabriz from the viewpoint of gastrointestinal helminthes infestation

    Directory of Open Access Journals (Sweden)

    Ali Eslami


    Full Text Available From July to October 2006, fecal samples were collected from 242 horses and ponies of Tabriz jockey clubs and 119 local equids in order to determine their EPG and parasitic fauna of gastrointestinal helminthes. After performing the Clayton- laen method of floatation test using zinc chloride and saturated sodium chloride solutions, it was determined that the feces of 40% of jockey club horses and 78.15% of local equids were infected by the eggs of parasitic gastrointestinal helminthes. Trichuris eggs were observed in 4.2% of the feces of local equids. Fecal culture revealed that all the eggs in the feces of jockey club horses were small strongyles while 2 of the local equids were infected by Strongyles vulgaris and the rest by small strongyles. Based on independent t-test, the differences between males and females and different age groups were insignificant.

  8. Modeling Financial Contagion using Copula

    Directory of Open Access Journals (Sweden)

    Pedro Luiz Valls Pereira


    Full Text Available This article aims to test the hypothesis of contagion between the indices of financial markets from the United States into Brazil, Japan and the UK for the 2000 to 2009 period. Time varying copulas were used to capture the impact of the sub-prime crisis in the dependence between markets. The implemented model was an ARMA(1,0 st-ARCH(1,2 to the marginal distributions and Normal and Joe-Clayton (SJC copulas for the joint distribution. The results obtained allow to conclude that both for the gaussian copula and for the SJC copula there is evidence of contagion between the US market and the Brazilian market. For the other two markets, the UK and Japan, the evidence of the presence of contagion between these markets and the US has not been sufficiently clear in both copula.

  9. Exploring the link between environmental identity, behaviors and decision making (United States)

    Freed, Allison

    This study was conducted with undergraduate students at a large university to investigate the association between environmental identity, pro-environmental behaviors and environmental decision-making. This study explored how environmental identity as defined by Clayton (2003) influenced the type of pro-environmental behaviors individuals choose to participate in. Environmental decision-making based on Kahneman's (2003, 2011) System 1 and System 2 framework was also assessed in association with environmental identity. A survey including the Environmental Identity Survey (Clayton, 2003), the Environmentally Responsible Behaviors Index (Smith-Sebasto & D'Acosta, 1995), and a Decision Making Questionnaire were administered. After administering the surveys, eight participants were chosen for a 60-minute interview. The quantitative results of the study showed there was a significant relationship between environmental identity and participating in environmental behaviors more often. There was also a significant relation between environmental identity and making the decision to recycle in a fast and automatic way. The interview results showed that participants with both a strong and a weak environmental identity recycled often and thought it was a fast decision. The results of this study show that certain components of environmental identity are important, but other factors like the physical environment and social norms influence the thinking that goes into recycling more than environmental identity alone. This study provides evidence of the importance of social norms and environmental structures in fostering pro-environmental behaviors and influencing the type of thinking that goes into making environmental decisions. Keywords: environmental identity, environmental behaviors, System 1, System 2, recycling.

  10. Teaching teamwork: an evaluation of an interprofessional training ward placement for health care students

    Directory of Open Access Journals (Sweden)

    Morphet J


    Full Text Available Julia Morphet,1 Kerry Hood,2 Robyn Cant,2 Julie Baulch,3 Alana Gilbee,3 Kate Sandry4 1School of Nursing and Midwifery, Monash University, Frankston, Victoria, Australia; 2School of Nursing and Midwifery, Monash University, Clayton, Victoria, Australia; 3Southern Clinical School, Monash University, Monash Health, Clayton, Victoria, Australia; 4Dandenong Emergency Department, Monash Health, David St, Dandenong, Victoria, Australia Abstract: The establishment of interprofessional teamwork training in the preprofessional health care curriculum is a major challenge for teaching faculties. Interprofessional clinical placements offer an opportunity for teamwork education, as students in various professions can work and learn together. In this sequential, mixed-method study, focus group and survey techniques were used to evaluate students' educational experiences after 2-week ward-based interprofessional clinical placements. Forty-five senior nursing, medicine, and other health care students cared for patients in hospital wards under professional supervision, with nursing-medicine student "teams" leading care. Thirty-six students attended nine exit focus groups. Five central themes that emerged about training were student autonomy and workload, understanding of other professional roles, communication and shared knowledge, interprofessional teamwork/collaboration, and the "inner circle", or being part of the unit team. The learning environment was described as positive. In a postplacement satisfaction survey (n=38, students likewise rated the educational experience highly. In practicing teamwork and collaboration, students were able to rehearse their future professional role. We suggest that interprofessional clinical placements be regarded as an essential learning experience for senior preprofessional students. More work is needed to fully understand the effect of this interactive program on students' clinical learning and preparation for practice

  11. Final Scientific/Technical Report – DE-EE0002960 Recovery Act. Detachment faulting and Geothermal Resources - An Innovative Integrated Geological and Geophysical Investigation of Pearl Hot Spring, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Stockli, Daniel F. [Univ. of Texas, Austin, TX (United States)


    The Pearl Host Spring Geothermal Project funded by the DoE Geothermal Program was a joint academic (KU/UT & OU) and industry collaboration (Sierra and Ram Power) to investigate structural controls and the importance of low-angle normal faults on geothermal fluid flow through a multifaceted geological, geophysical, and geochemical investigation in west-central Nevada. The study clearly showed that the geothermal resources in Clayton Valley are controlled by the interplay between low-angle normal faults and active deformation related to the Walker Lane. The study not only identified potentially feasible blind geothermal resource plays in eastern Clayton Valley, but also provide a transportable template for exploration in the area of west-central Nevada and other regional and actively-deforming releasing fault bends. The study showed that deep-seated low-angle normal faults likely act as crustal scale permeability boundaries and could play an important role in geothermal circulation and funneling geothermal fluid into active fault zones. Not unique to this study, active deformation is viewed as an important gradient to rejuvenated fracture permeability aiding the long-term viability of blind geothermal resources. The technical approach for Phase I included the following components, (1) Structural and geological analysis of Pearl Hot Spring Resource, (2) (U-Th)/He thermochronometry and geothermometry, (3) detailed gravity data and modeling (plus some magnetic and resistivity), (4) Reflection and Refraction Seismic (Active Source), (5) Integration with existing and new geological/geophysical data, and (6) 3-D Earth Model, combining all data in an innovative approach combining classic work with new geochemical and geophysical methodology to detect blind geothermal resources in a cost-effective fashion.

  12. Fungicide Efficacy in Peach Rusty Spot Control in Serbia

    Directory of Open Access Journals (Sweden)

    Nenad Dolovac


    Full Text Available Rusty Spot has long been known as a harmful peach disease in many parts of the world. During the past several years, rusty spot infection of the late-maturing peach cultivars (Summerset, Suncrest, Fayette and O’Henry caused significant yield losses in Serbia.Although the etiology of the disease is still unknown, there are numerous studies attempting to set a strategy for its control and recommend appropriate chemical and other peach protection methods. However, because of specific environmental conditions in Serbia, recommended protection method using repeated fungicide treatments, starting from petal fall, did not prove to be efficient and the rate of infection in some susceptible peach cultivars reached 100%. In 2003 and 2004 a field trial was conducted in order to test the efficacy of fungicides (a.i. kresoxim-methyl, flusilazole and sulfur for the efficient control of Rusty Spot epidemics. The trial was carried out under conditions of natural infection on the peach cv. Summerset at the locality of Bela Crkva, Serbia. In the ntreated control plots,high disease incidence was recorded with the percentage of affected fruit surface ranging from 33.5% in the first, up to the 35.4% in the second year of the trail. Among fungicides included in the trial, kresoxim-methyl proved to be the most efficient (90.25% in the first and 91.12% in the second year of the trial, flusilazole exhibited lower efficacy (87.28% and 80.61%, respectively while sulfur was the least efficient 82.33% and 80.30%, respectively. Determination of the most efficient fungicide for the peach rusty spot control in Serbia provides basic nformation for further investigations which will include optimization of treatment terms, as well as additional agro-technical control measures.


    Directory of Open Access Journals (Sweden)

    Natalia T. Pakhsarian


    Full Text Available The interest of contemporary literary theory and literary history in the problem of fictional space and in the space in the 18 th century novels in particular reveals both achievements and gaps in this field. The latest studies have shed light on the intimization and feminization of the fictional space in rococo novels and have defined the spatial units in such novels by Crébillon-fils as L’Écumoire ou Tanza ï et Néadarné, Le Sopha, and Les Égarements du cœur et de l’esprit. However, the inner-novel spatial relationships have been generally neglected. Juxtaposition of the topography of such novels as L’Astrée by Honoré d’Urfé, La Princesse de Clèves by Madame de La Fayette, and the novels by Crébillon-fils demonstrates that rhetorical theatricality of the baroque and classicist space had been replaced in these works by de-theatralization and topographical abstraction of rococo novels. Purely verbal, playful voyeurism of the novels by Crébillonfils does not match with topographical precision of pose and gesture as described in the frivolous erotic writings of the period (as, for example in “Thérèse-philosophe”. Transformation of rhetorical spatial topoi of the baroque and classicist periods occurs in the works of Crébillon-fils, as it does in the works of other authors of rocaille novels, through naturalizing and psychologizing the novel’s generic features.

  14. Collection of short papers on Beaver Creek watershed studies in West Tennessee, 1989-94 (United States)

    Doyle, W. Harry.; Baker, Eva G.


    In 1989, the U.S. Geological Survey began a scientific investigation to evaluate the effect of agricultural activities on water quality and the effectiveness of agricultural best management practices in the Beaver Creek watershed, West Tennessee. The project is being conducted jointly with other Federal, State, county agencies, the farming community, and academic institutions, in support of the U.S. Department of Agriculture's Hydrologic Unit Area program. The Beaver Creek project has evolved into a long-term watershed assessment and monitoring program. In 1991, a grant was received to develop and evaluate sampling strategies for higher order streams. During the summer of 1992, a reconnaissance of water-quality conditions for the shallow aquifers in Shelby, Tipton, Fayette, and Haywood Counties was conducted and included 89 domestic wells in the Beaver Creek watershed. Results from this effort lead to the development of a 1-year program to evaluate cause- and-effect relations that can explain the observed water-quality conditions for the shallow aquifers in the watershed. In 1992 the USGS, in cooperation with the Soil Conservation Service and the Shelby County Soil Conservation District, began an evaluation of in-stream processes and in-stream resource-management systems. In 1993, a biomonitoring program was established in the watershed. This collection of eight articles and abstracts was originally published in the American Water Resources Association National Symposium on Water Quality Proceedings for the national conference held in Chicago in 1994 and describes what has been learned in the study to date.

  15. Classic intrafascial supracervical hysterectomy (CISH): 10-year experience. (United States)

    Morrison, John E; Jacobs, Volker R


    We report and review herein our 10-year experience with classic intrafascial supracervical hysterectomy focusing on our long-term experience, evolution of the operative technique, and increased use of this technique. We performed a parallel, observational study with retrospective data to evaluate classic intrafascial supracervical hysterectomy, a laparoscopic hysterectomy technique, at Fayette Medical Center, a community hospital in Northwestern Alabama, USA. Patients comprised a consecutive series of 579 over a 10-year period from November 1992 through November 2002. The classic intrafascial supracervical hysterectomy technique, similar to standard supracervical hysterectomy, leaves the cardinal ligament, uterosacral ligament, vascular supply, and innervation to the upper vagina and cervix intact, but unlike supracervical hysterectomy removes the transition zone and endocervical canal. For 579 patients, the average age was 45.4 years (range, 22 to 92), follow-up was 75.3 months (range, 17 to 137), operating room time was 69 minutes (range, 44 to 370), blood loss was 72 mL (range, 10 to 765), length of hospital stay was 23.2 hours (range, 14 hours to 5 days), time to return to work was 13.2 days (range, 3 to 28). Complications include 11 cervical bleedings, 1 uterine artery bleeding, 1 pelvic hematoma, 1 postoperative ileus, and 16 mucoceles of the cervical stump. Three patients were converted from a laparoscopic to an open procedure (0.52%). Long-term follow-up of up to 137 months shows no adverse events thus far. Classic intrafascial supracervical hysterectomy is a safe procedure with a low short- and long-term complication rate. It has a short recuperation period and high patient satisfaction. It is the procedure of choice when hysterectomy is indicated for benign disease.

  16. Smoke-free laws, gender, and reduction in hospitalizations for acute myocardial infarction. (United States)

    Hahn, Ellen J; Rayens, Mary Kay; Burkhart, Patricia V; Moser, Debra K


    We examined gender differences in the incidence of acute myocardial infarction (AMI) after the passage of a smoke-free law in Lexington, Kentucky. The initial legislation had exemptions not covering manufacturing facilities and government buildings, which may have put men at greater risk for AMI. We examined the effect of Lexington's smoke-free public places law on hospitalizations for AMI (i.e., heart attack) among men and women 40 months prior to and 32 months after enactment of the law. We used the statewide administrative database (Comp Data) for all hospital billing records for the four health-care systems in Lexington-Fayette County. Cases were included in the analysis if (1) the patient was $35 years of age; (2) the patient had a primary discharge diagnosis of AMI, with an International Classification of Diseases, Ninth Revision code in the range of 410.00 to 410.99; and (3) the date of service was between January 1, 2001, and December 31, 2006. Among women, AMI hospitalizations declined 23% after the law took effect. The rate of AMI events among men did not change significantly. There was an overrepresentation of women in the hospitality industry and a disproportionate number of men working in manufacturing facilities and government worksites not mandated by the law. We found gender differences in the reduction of AMI hospitalizations following implementation of a smoke-free law that covered only some sectors of the workforce. Enacting smoke-free laws that cover all places of employment and strengthening existing partial laws may extend protection against AMIs to female and male workers.

  17. Hydrology of the Claiborne aquifer and interconnection with the Upper Floridan aquifer in southwest Georgia (United States)

    Gordon, Debbie W.; Gonthier, Gerard


    The U.S. Geological Survey conducted a study, in cooperation with the Georgia Environmental Protection Division, to define the hydrologic properties of the Claiborne aquifer and evaluate its connection with the Upper Floridan aquifer in southwest Georgia. The effort involved collecting and compiling hydrologic data from the aquifer in subarea 4 of southwestern Georgia. Data collected for this study include borehole geophysical logs in 7 wells, and two 72-hour aquifer tests to determine aquifer properties.The top of the Claiborne aquifer extends from an altitude of about 200 feet above the North American Vertical Datum of 1988 (NAVD 88) in Terrell County to 402 feet below NAVD 88 in Decatur County, Georgia. The base of the aquifer extends from an altitude of about 60 feet above NAVD 88 in eastern Sumter County to about 750 feet below NAVD 88 in Decatur County. Aquifer thickness ranges from about 70 feet in eastern Early County to 400 feet in Decatur County.The transmissivity of the Claiborne aquifer, determined from two 72-hour aquifer tests, was estimated to be 1,500 and 700 feet squared per day in Mitchell and Early Counties, respectively. The storage coefficient was estimated to be 0.0006 and 0.0004 for the same sites, respectively. Aquifer test data from Mitchell County indicate a small amount of leakage occurred during the test. Groundwater-flow models suggest that the source of the leakage was the underlying Clayton aquifer, which produced about 2.5 feet of drawdown in response to pumping in the Claiborne aquifer. The vertical hydraulic conductivity of the confining unit between the Claiborne and Clayton aquifers was simulated to be about 0.02 foot per day.Results from the 72-hour aquifer tests run for this study indicated no interconnection between the Claiborne and overlying Upper Floridan aquifers at the two test sites. Additional data are needed to monitor the effects that increased withdrawals from the Claiborne aquifer may have on future water resources.

  18. Results from the Big Spring basin water quality monitoring and demonstration projects, Iowa, USA (United States)

    Rowden, R.D.; Liu, H.; Libra, R.D.


    Agricultural practices, hydrology, and water quality of the 267-km2 Big Spring groundwater drainage basin in Clayton County, Iowa, have been monitored since 1981. Land use is agricultural; nitrate-nitrogen (-N) and herbicides are the resulting contaminants in groundwater and surface water. Ordovician Galena Group carbonate rocks comprise the main aquifer in the basin. Recharge to this karstic aquifer is by infiltration, augmented by sinkhole-captured runoff. Groundwater is discharged at Big Spring, where quantity and quality of the discharge are monitored. Monitoring has shown a threefold increase in groundwater nitrate-N concentrations from the 1960s to the early 1980s. The nitrate-N discharged from the basin typically is equivalent to over one-third of the nitrogen fertilizer applied, with larger losses during wetter years. Atrazine is present in groundwater all year; however, contaminant concentrations in the groundwater respond directly to recharge events, and unique chemical signatures of infiltration versus runoff recharge are detectable in the discharge from Big Spring. Education and demonstration efforts have reduced nitrogen fertilizer application rates by one-third since 1981. Relating declines in nitrate and pesticide concentrations to inputs of nitrogen fertilizer and pesticides at Big Spring is problematic. Annual recharge has varied five-fold during monitoring, overshadowing any water-quality improvements resulting from incrementally decreased inputs. ?? Springer-Verlag 2001.

  19. 1998 astronaut candidates tour CCAS facilities copy form; photos beginning with 99PD are only availa (United States)


    At Cape Canaveral Air Station, members of the 1998 astronaut candidate class (Group 17) pose in front of what remains of the launch tower at Launch Complex 34 during a tour of the station's facilities. During the Apollo Program, Launch Complex 34 was the site of the first Saturn I and Saturn IB launches, as well as the tragic fire in which the Apollo I astronauts lost their lives. The class is at Kennedy Space Center taking part in training activities, including a flight awareness program, as well as touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  20. 1998 astronaut candidates tour CCAS facilities (United States)


    At Cape Canaveral Air Station, members of the 1998 astronaut candidate class (Group 17) pose in front of the Project Mercury monument at Launch Complex 14 during a tour of the station's facilities. This 13-foot-high astronomical symbol for the planet Mercury was constructed by General Dynamics, the Atlas airframe contractor, and dedicated in 1964 in honor of those who flew in the Mercury 7 capsule. The class is at Kennedy Space Center taking part in training activities, including a flight awareness program, as well as touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Tracy E. Caldwell (Ph.D.), Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  1. 1998 astronaut candidates tour KSC facilities (United States)


    On the grounds of the Kennedy Space Center, members of the 1998 astronaut candidate class (Group 17) watch as candidate Tracy E. Caldwell (Ph.D.) practices using firefighting equipment during fire training. The class is at KSC for training activities, including a flight awareness program, plus touring the OPF, VAB, SSPF, SSME Processing Facility, launch pads, SLF, Apollo/Saturn V Center, and the crew quarters. The other U.S. candidates in the '98 class are Clayton C. Anderson, Lee J. Archambault, Gregory E. Chamitoff (Ph.D.), Timothy J. Creamer, Christopher J. Ferguson, Michael J. Foreman, Michael E. Fossum, Kenneth T. Ham, Patricia C. Hilliard (M.D.), Gregory C. Johnson, Gregory H. Johnson, Stanley G. Love (Ph.D.), Leland D. Melvin, Barbara R. Morgan, William A. Oefelein, John D. Olivas (Ph.D.), Nicholas J.M. Patrick (Ph.D.), Alan G. Poindexter, Garrett E. Reisman (Ph.D.), Steven R. Swanson, Douglas H. Wheelock, Sunita L. Williams, Neil W. Woodward III, George D. Zamka; and the international candidates are Leopold Eyharts, Paolo Nespoli, Hans Schlegel, Roberto Vittori, Bjarni V. Tryggvason, and Marcos Pontes.

  2. To Think and Watch the Evil: The Turn of the Screw as Cultural Reference in Television from Dark Shadows to C.S.I.

    Directory of Open Access Journals (Sweden)

    Anna Viola Sborgi


    Full Text Available Since its first publication, Henry James’s The Turn of the Screw (1898 has always haunted the imagination of artists (Benjamin Britten, Jack Clayton, Amenábar and has been widely used as a source for television narratives (Dan Curtis, US TV version starring Colin Firth, Tim Fywell. In serial productions, James’s story has been the object of extensive quotation and allusion, from the 1960 gothic soap opera Dark Shadows to the C.S.I. episode Turn of the Screw (Season 4, Episode 21. A milestone in literary history, the story now embodies a set of cultural references conveying different, complex meanings, which can only be disclosed in the light of contemporary forms of representing reality. The novella appeals to two apparently opposite tendencies in contemporary television: the morbid display of the real (C.S.I. and the quest for the supernatural (Buffy The Vampire Slayer, among others. A line can be traced from Dark Shadows, the show that pioneered the genre, to contemporary horror soaps about vampires and supernatural phenomena. This paper shows the ways in which James’ sophisticated novella makes its way through popular culture, and how its constant ambiguous, dilemmatic interplay between reality and imagination can be related to the double-sided drive of the contemporary public towards hyper-reality and the supernatural.

  3. Simplex optimization of the variables influencing the determination of pefloxacin by time-resolved chemiluminescence (United States)

    Murillo Pulgarín, José A.; Alañón Molina, Aurelia; Jiménez García, Elisa


    A new chemiluminescence (CL) detection system combined with flow injection analysis (FIA) for the determination of Pefloxacin is proposed. The determination is based on an energy transfer from Pefloxacin to terbium (III). The metal ion enhances the weak CL signal produced by the KMnO4/H2SO3/Pefloxacin system. A modified simplex method was used to optimize chemical and instrumental variables. The influence of the interaction of the permanganate, Tb (III), sodium sulphite and sulphuric acid concentrations, flow rate and injected sample volume was thoroughly investigated by using a modified simplex optimization procedure. The results revealed a strong direct relationship between flow rate and CL intensity throughout the studied range that was confirmed by a gamma test. The response factor for the CL emission intensity was used to assess performance in order to identify the optimum conditions for maximization of the response. Under such conditions, the CL response was proportional to the Pefloxacin concentration over a wide range. The detection limit as calculated according to Clayton's criterion 13.7 μg L- 1. The analyte was successfully determined in milk samples with an average recovery of 100.6 ± 9.8%.

  4. Learning to forecast wind at remote sites for wind energy applications. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Notis, C.; Trettel, D.W.; Aquino, J.T.; Piazza, T.R.; Taylor, L.E.; Trask, D.C.; Wegley, H.L.; Miller, A.H.


    Observed wind patterns are correlated with synoptic or mescoscale weather systems. Six sites selected for analysis include Montauk Point, New York; Boone, North Carolina; Ludington, Michigan; Clayton, New Mexico; Amarillo, Texas; and San Gorgonio Pass, California. Objectives of the analysis are: to identify synoptic and/or mesoscale weather patterns that are associated with recognizable wind events at the sites; to define a set of criteria that uniquely describes such weather patterns; to estimate the reliability (accuracy) of forecasting rules derived from the association of weather patterns and site winds; and to attempt to separate any mesoscale effects of local topography from the synoptic-scale effects. One-to-one mapping of wind regimes onto synoptic types was not found. It was concluded that four factors should be examined when stratifying wind regimes: synoptic situation, descriptive climatology, pressure gradient vector, and winds aloft. The wind forecasting approach developed was intended for forecasting hourly average winds out to the 24 hour or possibly 36 hour time horizon. (LEW)

  5. Treatment of a traumatic atrophic depressed scar with hyaluronic acid fillers: a case report

    Directory of Open Access Journals (Sweden)

    Hussain SN


    Full Text Available Syed Nazim Hussain,1 Greg J Goodman,2,3 Eqram Rahman4 1Royal Lush Skin Hair & Laser Clinic, Saket, New Delhi, India; 2Department of Primary Care, Monash University, Clayton, 3Skin and Cancer Foundation Inc, Carlton, VIC, Australia; 4Faculty of Medical Science, Postgraduate Medical Institute, Anglia Ruskin University, Chelmsford, UK Background: Hyaluronic acid filler has been documented in the treatment of atrophic depressed acne scars relatively frequently in the literature but rarely in chronic depressed traumatic atrophic facial scars.Methods: This case report discusses the use of hyaluronic acid fillers in the correction of a post-traumatic facial atrophic scar on the right cheek.Results: The right cheek scar was substantially corrected with one session of two different hyaluronic acids injected in a deep and superficial plane.Conclusion: Relatively accurate, simple and effective correction of this atrophic traumatic scar may suggest that fillers are a suitable alternative to surgery for such scars. Keywords: scarring, scar correction, filler, hyaluronic acid, facial scar

  6. Volatility spillover between crude oil and exchange rate: A copula-CARR approach (United States)

    Pu, Y. J.; Guo, M. Y.


    Oil provides a powerful impetus for modern society's production and life. The influences of oil price fluctuations on socio-economic development are obvious, and it draws more attention from scholars. However, the distribution of oil is highly centralized, which leads to the vast majority of oil trading through foreign trade. As a result, exchange rate plays an important role in the oil business. Study on the relationship between exchange rate and crude oil gradually becomes a hot research topic in recent years. In this paper, we use copula and CARR model to study correlation structure and relationship between crude oil price and exchange rate. We establish CARR models as marginal models and use five copulas which are Gaussian Copula, Student-t Copula, Gumbel Copula, Clayton Copula and Frank Copula to study the correlation structure between NYMEX crude oil price range and U. S. Dollar Index range. Furthermore, we use Copula-CARR model with structural breaks to detect the change points in the correlation structure between NYMEX crude oil price range and U. S. Dollar Index range. Empirical results show that the change points are closely related to the actual economic events.

  7. Can CCM law properly represent all extinction curves?

    International Nuclear Information System (INIS)

    Geminale, Anna; Popowski, Piotr


    We present the analysis of a large sample of lines of sight with extinction curves covering wavelength range from near-infrared (NIR) to ultraviolet (UV). We derive total to selective extinction ratios based on the Cardelli, Clayton and Mathis (1989, CCM) law, which is typically used to fit the extinction data both for diffuse and dense interstellar medium. We conclude that the CCM law is able to fit most of the extinction curves in our sample. We divide the remaining lines of sight with peculiar extinction into two groups according to two main behaviors: a) the optical/IR or/and UV wavelength region cannot be reproduced by the CCM formula; b) the optical/NIR and UV extinction data are best fit by the CCM law with different values of R v . We present examples of such curves. The study of both types of peculiar cases can help us to learn about the physical processes that affect dust in the interstellar medium, e.g., formation of mantles on the surface of grains, evaporation, growing or shattering

  8. Tail dependence and information flow: Evidence from international equity markets (United States)

    Al Rahahleh, Naseem; Bhatti, M. Ishaq; Adeinat, Iman


    Bhatti and Nguyen (2012) used the copula approach to measure the tail dependence between a number of international markets. They observed that some country pairs exhibit only left-tail dependence whereas others show only right-tail. However, the flow of information from uni-dimensional (one-tail) to bi-dimensional (two-tails) between various markets was not accounted for. In this study, we address the flow of information of this nature by using the dynamic conditional correlation (DCC-GARCH) model. More specifically, we use various versions of the DCC models to explain the nexus between the information flow of international equity and to explain the stochastic forward vs. backward dynamics of financial markets based on data for a 15-year period comprising 3,782 observations. We observed that the information flow between the US and Hong Kong markets and between the US and Australian markets are bi-directional. We also observed that the DCC model captures a wider co-movement structure and inter-connectedness compared to the symmetric Joe-Clayton copula.

  9. On the reliability of Quake-Catcher Network earthquake detections (United States)

    Yildirim, Battalgazi; Cochran, Elizabeth S.; Chung, Angela I.; Christensen, Carl M.; Lawrence, Jesse F.


    Over the past two decades, there have been several initiatives to create volunteer‐based seismic networks. The Personal Seismic Network, proposed around 1990, used a short‐period seismograph to record earthquake waveforms using existing phone lines (Cranswick and Banfill, 1990; Cranswicket al., 1993). NetQuakes (Luetgert et al., 2010) deploys triaxial Micro‐Electromechanical Systems (MEMS) sensors in private homes, businesses, and public buildings where there is an Internet connection. Other seismic networks using a dense array of low‐cost MEMS sensors are the Community Seismic Network (Clayton et al., 2012; Kohler et al., 2013) and the Home Seismometer Network (Horiuchi et al., 2009). One main advantage of combining low‐cost MEMS sensors and existing Internet connection in public and private buildings over the traditional networks is the reduction in installation and maintenance costs (Koide et al., 2006). In doing so, it is possible to create a dense seismic network for a fraction of the cost of traditional seismic networks (D’Alessandro and D’Anna, 2013; D’Alessandro, 2014; D’Alessandro et al., 2014).

  10. Disruptive innovation for social change. (United States)

    Christensen, Clayton M; Baumann, Heiner; Ruggles, Rudy; Sadtler, Thomas M


    Countries, organizations, and individuals around the globe spend aggressively to solve social problems, but these efforts often fail to deliver. Misdirected investment is the primary reason for that failure. Most of the money earmarked for social initiatives goes to organizations that are structured to support specific groups of recipients, often with sophisticated solutions. Such organizations rarely reach the broader populations that could be served by simpler alternatives. There is, however, an effective way to get to those underserved populations. The authors call it "catalytic innovation." Based on Clayton Christensen's disruptive-innovation model, catalytic innovations challenge organizational incumbents by offering simpler, good-enough solutions aimed at underserved groups. Unlike disruptive innovations, though, catalytic innovations are focused on creating social change. Catalytic innovators are defined by five distinct qualities. First, they create social change through scaling and replication. Second, they meet a need that is either overserved (that is, the existing solution is more complex than necessary for many people) or not served at all. Third, the products and services they offer are simpler and cheaper than alternatives, but recipients view them as good enough. Fourth, they bring in resources in ways that initially seem unattractive to incumbents. And fifth, they are often ignored, put down, or even encouraged by existing organizations, which don't see the catalytic innovators' solutions as viable. As the authors show through examples in health care, education, and economic development, both nonprofit and for-profit groups are finding ways to create catalytic innovation that drives social change.

  11. Use of recombinant human antithrombin concentrate in pregnancy

    Directory of Open Access Journals (Sweden)

    Baumann Kreuziger LM


    Full Text Available Lisa M Baumann Kreuziger,1 Tracy L Prosen,2 Mark T Reding1 1Division of Hematology, Oncology, and Transplantation, University of Minnesota, MN, USA; 2Obstetrics and Gynecology, Maternal Fetal Medicine Center, University of Minnesota, MN, USAWe read with great interest James et al’s article "Prevention and treatment of venous thromboembolism in pregnancy in patients with hereditary antithrombin deficiency." The authors reported a case series of six women with antithrombin (AT deficiency treated with plasma derived antithrombin concentrate (pdAT; Thrombate III®, Grifols Therapeutics, Clayton, NC, USA.1 In contrast to these cases, we have managed three AT-deficient women over the past two years with low-molecular-weight-heparin during pregnancy and recombinant human antithrombin concentrate (rhAT; ATryn®, GTC Biotherapeutics, Framingham, MA, USA at delivery. In the Phase III trial leading to approval of rhAT, pregnant women required frequent dose modifications, and an alternate dosing regimen is currently recommended by the manufacturer.2,3 The detailed information provided in these cases may assist future providers in managing pregnant patients with AT deficiency.View original paper by James and colleagues.

  12. Higroscopicidade das sementes de pimenta (Capsicum chinense L.

    Directory of Open Access Journals (Sweden)

    Hellismar W. da Silva


    Full Text Available RESUMOA higroscopicidade de sementes fornece informações essenciais para otimização de processos de secagem, armazenamento e desenvolvimento de embalagens. O objetivo neste trabalho foi determinar as isotermas de dessorção das sementes de pimenta (Capsicum chinense L., variedade Cabacinha, para diferentes condições de temperatura e atividade de água utilizando-se o método estático indireto, sendo a atividade de água (aw determinada por meio do equipamento Hygropalm Model Aw1. Aos dados experimentais foram ajustados modelos matemáticos frequentemente utilizados para representação da higroscopicidade de produtos agrícolas. Para uma atividade de água constante o aumento da temperatura reduz o teor de água de equilíbrio higroscópico das sementes de pimenta. As isotermas de dessorção apresentam formato sigmoidal do tipo II. Os modelos de Cavalcanti Mata, Chen Clayton, Chung Pfost, Chung Pfost Modificado, Henderson e Henderson Modificado são adequados para representar a higroscopicidade das sementes de pimenta Cabacinha para a faixa de temperatura de 10 a 40 °C e atividade de água de 0,213 a 0,975.

  13. Illusionismo e magia nel ‘Golden Age Mystery’

    Directory of Open Access Journals (Sweden)

    Stefano Serafini


    Full Text Available The Golden Age of detective fiction, usually delimitated between 1914 and 1940, coincides with the Golden Age of theatrical magic. Mystery and magic are linked by various elements such as the persistence of the challenge (between writer and readers or between magician and audience, the power of suggestion, the role of the stage and the attraction towards the impossible. Mystery writing and stage magic both rely on conjuring tricks, devices and misdirection. Starting from this premise, I will discuss two different ways in which theatrical magic has influenced Golden Age writers. While writers such as John Dickson Carr, Hake Talbot and Clayton Rawson – mostly from the United States – would thematise magic, others made an “illusionistic” use of language and narrative in order to confound and misdirect the readers. This technique – which is ultimately rooted in Edgar Allan Poe’s work – recurs in Agatha Christie’s books, where “the quickness of the hand deceives the eye”.

  14. Interdependence between Greece and other European stock markets: A comparison of wavelet and VMD copula, and the portfolio implications (United States)

    Shahzad, Syed Jawad Hussain; Kumar, Ronald Ravinesh; Ali, Sajid; Ameer, Saba


    The interdependence of Greece and other European stock markets and the subsequent portfolio implications are examined in wavelet and variational mode decomposition domain. In applying the decomposition techniques, we analyze the structural properties of data and distinguish between short and long term dynamics of stock market returns. First, the GARCH-type models are fitted to obtain the standardized residuals. Next, different copula functions are evaluated, and based on the conventional information criteria and time varying parameter, Joe-Clayton copula is chosen to model the tail dependence between the stock markets. The short-run lower tail dependence time paths show a sudden increase in comovement during the global financial crises. The results of the long-run dependence suggest that European stock markets have higher interdependence with Greece stock market. Individual country's Value at Risk (VaR) separates the countries into two distinct groups. Finally, the two-asset portfolio VaR measures provide potential markets for Greece stock market investment diversification.

  15. Gaan na die mier, kyk na sy weë en word wys: Metafoor of paradigma?

    Directory of Open Access Journals (Sweden)

    Johan Buitendag


    Full Text Available Go to the ant, consider her ways, and be wise. Metaphor or paradigm? This article takes as its point of departure two citations. The one is from Marshall and Zohar’s contention that the wave-particle dualism is more than a metaphor and the other is from Clayton claiming that indeterminacy was not merely a temporary epistemic problem, but reflected an inherent indeterminacy of the physical world itself. What does it mean if it is not a mere way of speaking? The author of this article departs from the premise that the task of systematic theology is the endeavour to understand reality and that this is a collective enterprise together with other sciences as well. A constructive empiricism could indeed lead to an understanding of reality where reality is more than merely idealistically conceived. Truth is therefore to be replaced with a pragmatic, but value-laden concept of understanding or comprehension. This has the effect that both epistemology and ontology have to be revisited and subsequently panentheism too. The argument finds its niche in Old Testament wisdom literature and Proverbs 6:6 forms the lens of reference. The late South African ethologist Eugène Marais’s epic work, The Soul of the Ant, is applied to illustrate such a proposed epistemic community.

  16. Flood of May 23, 2004, in the Turkey and Maquoketa River basins, northeast Iowa (United States)

    Eash, David A.


    Severe flooding occurred on May 23, 2004, in the Turkey River Basin in Clayton County and in the Maquoketa River Basin in Delaware County following intense thunderstorms over northeast Iowa. Rain gages at Postville and Waucoma, Iowa, recorded 72-hour rainfall of 6.32 and 6.55 inches, respectively, on May 23. Unofficial rainfall totals of 8 to 10 inches were reported in the Turkey River Basin. The peak discharge on May 23 at the Turkey River at Garber streamflow-gaging station was 66,700 cubic feet per second (recurrence interval greater than 500 years) and is the largest flood on record in the Turkey River Basin. The timing of flood crests on the Turkey and Volga Rivers, and local tributaries, coincided to produce a record flood on the lower part of the Turkey River. Three large floods have occurred at the Turkey River at Garber gaging station in a 13-year period. Peak discharges of the floods of June 1991 and May 1999 were 49,900 cubic feet per second (recurrence interval about 150 years) and 53,900 cubic feet per second (recurrence interval about 220 years), respectively. The peak discharge on May 23 at the Maquoketa River at Manchester gaging station was 26,000 cubic feet per second (recurrence interval about 100 years) and is the largest known flood in the upper part of the Maquoketa River Basin.


    Directory of Open Access Journals (Sweden)

    Inna Stoliarenko


    Full Text Available The term "blended learning" described by domestic and foreign scientists is considered in the article. A number of advantages of blended learning have been marked out in comparison with traditional one: flexibility, learning personification, increase of motivation of students to training, variety of forms of arrangement of educational process and forms of presentation of teaching material and increase of efficiency of activity of the teacher. A set of key competencies a teacher should possess to support effective activity in the mixed educational environment has been analyzed. The scientists of the Learning Accelerator organization engaged in support of introduction of blended learning in American schools presented it. It is determined that its main difference from a teacher who uses traditional methods and training forms – desire to experiment, introducing various innovative pedagogical technologies in educational process to achieve maximum result. There is also a desire to create favorable conditions for successful learning of each student considering strong and weak sides. The scientists of Clayton Christensen Institute designed the models of organization of blended learning. These models were analyzed. Two expedient models for implementation in higher school, in particular, in preparation of future teachers of informatics have been defined: station rotation and "flipped classroom".

  18. Kinetic and morphology study of alginate-vineyard pruning waste biocomposite vs. non modified vineyard pruning waste for dye removal. (United States)

    Vecino, Xanel; Devesa-Rey, Rosa; Villagrasa, Salvador; Cruz, Jose M; Moldes, Ana B


    In this work a comparative bioadsorption study between a biocomposite consisting of hydrolysed vineyard pruning waste entrapped in calcium alginate spheres and non entrapped vineyard residue was carried out. Results have demonstrated that the biocomposite based on lignocellulose-calcium alginate spheres removed 77.3% of dyes, while non entrapped lignocellulose eliminated only removed 27.8% of colour compounds. The experimental data were fitted to several kinetic models (pseudo-first order, pseudo-second order, Chien-Clayton model, intraparticle diffusion model and Bangham model); being pseudo-second order the kinetic model that better described the adsorption of dyes onto both bioadsorbents. In addition, a morphological study (roughness and shape) of alginate-vineyard biocomposite was established under extreme conditions, observing significant differences between hydrated and dehydrated alginate-vineyard biocomposite. The techniques used to carry out this morphological study consisted of scanning electron microscopy (SEM), perfilometry and 3D surface analysis. Copyright © 2015. Published by Elsevier B.V.

  19. Removal of pigments from aqueous solution by a calcium alginate-grape marc biopolymer: a kinetic study. (United States)

    Perez-Ameneiro, M; Vecino, X; Barbosa-Pereira, L; Cruz, J M; Moldes, A B


    In this work, the potential use of a biopolymer based on grape marc entrapped in calcium alginate beads for the removal of pigments from an agro industrial effluent was evaluated. The parameters that affect the pigment adsorption such as pH (3.5-7.0), temperature (10-40°C) and initial pigment concentration (6.9-55.1mg/L) were studied by applying an incomplete factorial design. The dependent variables evaluated consisted of color effluent parameters from CIELAB and Tristimulus system, as well as the concentration of pigments in the wastewater after the adsorption treatment. The most significant independent variables tested were the pigments concentration followed by pH, whereas temperature had a negligible effect on the adsorption process. Moreover, at the optimal operational conditions (pH 3.5 and room temperature) kinetic studies were carried out by applying pseudo-first order, pseudo-second order, Chien-Clayton and intraparticle diffusion models, observing a good agreement between theoretical and experimental results. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. A hybrid absorbing boundary condition for frequency-domain finite-difference modelling

    International Nuclear Information System (INIS)

    Ren, Zhiming; Liu, Yang


    Liu and Sen (2010 Geophysics 75 A1–6; 2012 Geophys. Prospect. 60 1114–32) proposed an efficient hybrid scheme to significantly absorb boundary reflections for acoustic and elastic wave modelling in the time domain. In this paper, we extend the hybrid absorbing boundary condition (ABC) into the frequency domain and develop specific strategies for regular-grid and staggered-grid modelling, respectively. Numerical modelling tests of acoustic, visco-acoustic, elastic and vertically transversely isotropic (VTI) equations show significant absorptions for frequency-domain modelling. The modelling results of the Marmousi model and the salt model also demonstrate the effectiveness of the hybrid ABC. For elastic modelling, the hybrid Higdon ABC and the hybrid Clayton and Engquist (CE) ABC are implemented, respectively. Numerical simulations show that the hybrid Higdon ABC gets better absorption than the hybrid CE ABC, especially for S-waves. We further compare the hybrid ABC with the classical perfectly matched layer (PML). Results show that the two ABCs cost the same computation time and memory space for the same absorption width. However, the hybrid ABC is more effective than the PML for the same small absorption width and the absorption effects of the two ABCs gradually become similar when the absorption width is increased. (paper)

  1. Renal colic and childbirth pain: female experience versus male perception

    Directory of Open Access Journals (Sweden)

    Miah S


    Full Text Available Saiful Miah,1,2 Charlotte Gunner,3 Lucy Clayton,4 Suresh Venugopal,5 Nigel R Boucher,5 Bo Parys61Division of Surgery and Interventional Science, University College London, London, UK; 2Urology Department, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK; 3Urology Department, Raigmore Hospital, Inverness, UK; 4Psychiatry Department, Highbury Hospital, Nottingham, UK; 5Urology Department, Chesterfield Royal Infirmary, Chesterfield, UK; 6Urology Department, Rotherham General Hospital, Rotherham, UKIntroductionRenal colic is often described by patients as the worst pain ever experienced.1 Pain during childbirth is also similarly described.2 To date, no study has comparatively evaluated the pain of renal colic to that of childbirth in female patients who have experienced both. Furthermore, no such study has evaluated the perception that men with renal colic have with respect to the pain experienced during childbirth. Here we present our cross-sectional observational study to address these questions. The primary objectives of our study were to answer these questions and highlight the severity of renal colic which is not always faced and treated aggressively.  

  2. Measuring workplace trauma response in Australian paramedics: an investigation into the psychometric properties of the Impact of Event Scale

    Directory of Open Access Journals (Sweden)

    Hogan N


    Full Text Available Nicola Hogan,1 Shane Costello,1 Malcolm Boyle,2 Brett Williams2 1Faculty of Education, Monash University, Clayton, VIC, Australia; 2Department of Community Emergency Health and Paramedic Practice, Monash University, Frankston, VIC, Australia Introduction: Investigation into the psychological effects of violence toward health care workers and its associated trauma is increasing. The Impact of Event Scale (IES provides a measure of current, subjective, emotional distress symptomatic of a specific traumatic event. However, its validity among paramedics is largely unknown. Problem: The purpose of this study was to investigate the psychometric properties and factor structure of the IES with a sample of Australian paramedics. Methods: The study aimed to investigate the psychometric properties and factor structure of the 15-item IES with a sample of Australian paramedics using Exploratory Factor Analysis with model fit statistics as found in confirmatory analysis. Results: Maximum Likelihood Factor Analysis with Varimax rotation supported the hypothesis that a two-factor solution would provide the best fit of the data. Procrustes rotation provided further support for this hypothesis indicating that the factors, labeled “Intrusion” and “Avoidance”, as well as the individual items of the 12-item final model, were a good fit to an ideal solution. Conclusion: The revision of the scale has improved its validity for use in the general population of paramedics, improving the potential for its use in trauma-related research. Keywords: impact of event scale, psychometrics, paramedics, occupational violence, PTSD

  3. Panel: challenging criminal charges for HIV transmission and exposure. (United States)

    Edwardh, Marlys; Adam, Barry; Joncas, Lucie; Clayton, Michaela


    Justice Edwin Cameron, of the Constitutional Court of South Africa, served as moderator. He said that this topic was particularly relevant for "an African/Canadian setting" because African countries may use Canadian developments as justification for their efforts to address HIV transmission and exposure through criminal law. Justice Cameron said that Canada is internationally perceived as a human rights-respecting state and, thus, sets an example, particularly for African nations, on how to comply with human rights issues. He added that in this particular case, however, Canada was sending the wrong message. This article contains summaries of the four presentations made during this panel. Marlys Edwardh reviews how the Supreme Court of Canada in Cuerrier interpreted the concepts of "endangering life" and "fraud". Barry Adam discusses the notion of a "duty to disclose" and how this affects HIV prevention. Lucie Joncas examines how the Supreme Court defined "fraud" in Cuerrier and describes a case before the Quebec Court of Appeal which may turn on whether the use of a condom or having a low viral load is considered not to constitute a significant risk of transmission. Finally, Michaela Clayton describes the trend in Southern African countries to adopt laws criminalizing HIV transmission or exposure, and explains that criminalization endangers women's health and lives.

  4. A Quantitative, Time-Dependent Model of Oxygen Isotopes in the Solar Nebula: Step one (United States)

    Nuth, J. A.; Paquette, J. A.; Farquhar, A.; Johnson, N. M.


    The remarkable discovery that oxygen isotopes in primitive meteorites were fractionated along a line of slope I rather than along the typical slope 0,52 terrestrial fractionation line occurred almost 40 years ago, However, a satisfactory, quantitative explanation for this observation has yet to be found, though many different explanations have been proposed, The first of these explanations proposed that the observed line represented the final product produced by mixing molecular cloud dust with a nucleosynthetic component, rich in O-16, possibly resulting from a nearby supernova explosion, Donald Clayton suggested that Galactic Chemical Evolution would gradually change the oxygen isotopic composition of the interstellar grain population by steadily producing O-16 in supernovae, then producing the heavier isotopes as secondary products in lower mass stars, Thiemens and collaborators proposed a chemical mechanism that relied on the availability of additional active rotational and vibrational states in otherwise-symmetric molecules, such as CO2, O3 or SiO2, containing two different oxygen isotopes and a second, photochemical process that suggested that differential photochemical dissociation processes could fractionate oxygen , This second line of research has been pursued by several groups, though none of the current models is quantitative,

  5. Survey of gastrointestinal parasites in wild boar (Sus scrofa, wild goat (Capra aegagrus and red deer (Cervus elaphus in the Aynaloo protected area, East Azerbaijan province

    Directory of Open Access Journals (Sweden)

    Roghayeh Norouzi


    Full Text Available Parasitic infections are a threat to the wildlife by endangering the health of wild animals and serving as a source of transmission of infectious agents to livestock and humans. Despite the distribution of wild boars (Sus scrofa, wild goat (Capra aegagrus and red deer (Cervus elaphus throughout the world, information on their parasitic infections is limited. Knowledge of the parasitic fauna of animals in protected areas may be used in protection of endangered species. The present study aimed to investigate the status of gastrointestinal parasitic infections in wild boar, wild goat and red deer in the Aynaloo protected area, Northwest of Kaleybar city, East Azerbaijan province. For this purpose, in spring 2015, 30 fecal samples of wild boar, 30 fecal samples of wild goat and 30 fecal samples of red deer were collected. The samples were processed using direct smear and Clayton lane floatation technique. Five species of helminths were detected from wild boar fecal samples consisting of Trichuris suis, Strongyloides suis, Physocephalus sexalatus, Ascaris suum and Metastrongylus apri. Among them,  one species (Strongyloides suis was reported for the first time in Iran. Protozoa were not detected in the fecal samples of the wild boar. Wild goats were infected with Oesophagostomum columbianum, Muellerius capillaris and Eimeria spp. Respiratory larva and Eimeria spp. were detected from red deer samples.

  6. Dysfunctional attitudes, self-esteem, and hassles: cognitive vulnerability to depression in children of affectively ill parents. (United States)

    Abela, John R Z; Skitch, Steven A


    The current study tested the diathesis-stress component of Beck's [(1967). Depression: Clinical, experimental, and theoretical aspects. New York: Harper & Row, (1983). Cognitive therapy of depression: New perspectives. In P.J. Clayton, J.E. Barnett (Eds.), Treatment of depression: Old controversies and new approaches (pp. 265-290). New York: Raven Press] cognitive theory of depression in a sample of children between the ages of 6 and 14. We also examined whether high self-esteem buffers cognitively vulnerable youth against experiencing increases in depressive symptoms following increases in hassles. To provide a effective test of hypotheses, an at-risk sample (children of parents with a history of major depressive episodes) and a multi-wave longitudinal design were used. At Time 1, children (n=140) completed measures assessing dysfunctional attitudes, self-esteem, and depressive symptoms. Every 6 weeks for the next year, children completed measures assessing depressive symptoms and hassles. Hierarchical linear modeling analyses indicated that children possessing high levels of dysfunctional attitudes and low levels of self-esteem reported greater elevations in depressive symptoms following elevations in hassles than other children.

  7. Chemical Engineering Division physical inorganic chemistry annual report, July 1974--June 1975

    International Nuclear Information System (INIS)

    Blander, M.; Cajigas, C.J.; Huang, H.S.


    Thermal conductivity measurements of methanol vapor were made in a hot-wire cell at temperatures ranging from 306 to 345 0 K and pressures from 80 to 760 torr. Emf measurements of the activities of Li in Li-Mg alloys indicate small negative deviations from ideal behavior. Conformal ionic solution theory has been extended to fourth order for additive ternary molten salt systems (AX-BX-CX). A miscibility isotherm at 540 0 C for the Na,Ag parallel NO 3 ,Br system measured by a visual titration method appears to be consistent with theoretical considerations. Certain phase relationships in the systems, Li-Fe-S, Li-Cu-Fe-S, and Li-Co-Fe-S at 400 0 C, which are of interest to the lithium/metal sulfide battery program, were investigated. Emf measurements of Li-Al alloys relative to lithium were made. A value for the free energy of formation of Li 2 C 2 was obtained from emf measurements. A study of the crystallization of metastable supercooled molten MgO-SiO 2 droplets was made as a function of composition and temperatures. An examination of the diffusion of oxygen isotopes in mineral grains indicates that the oxygen isotope anomalies found by Clayton et al., in inclusions in the Allende meteorite appear to have been formed by diffusion of 17 O and 18 O into materials very low in these isotopes

  8. Age structure of refractory interstellar dust and isotopic consequences (United States)

    Clayton, Donald D.; Scowen, Paul; Liffman, Kurt


    A sputtering and recycling Monte Carlo model, developed by Liffman and Clayton (1988) is used to calculate the distribution of existence times of the matter in interstellar dust composed of refractory metals. The mean age of each dust particle is defined not as the time it has existed but rather as the mass-weighted existence times of its parts at t = 6 Gyr of the modeled solar system formation. It is shown that Galactic evolution generates a mean correlation, applying to large numbers of particles binned according to size rather than according to individual particles, whose mean ages fluctuate statistically. The cosmochemical consequence is that if interstellar particles can be dynamically sorted into separate size populations during the aggregation history of solar system bodies, the collections of larger grains will constitute matter that is chemically older than collections of smaller grains. The macroscopic age difference generates isotopic anomalies by virtue of the time dependence of the secondary/primary nucleosynthesis yields. Results are compared with three different prescriptions for the sputtering of interstellar dust.

  9. On Al-26 and other short-lived interstellar radioactivity (United States)

    Clayton, Donald D.; Hartmann, Dieter H.; Leising, Mark D.


    Several authors have shown that massive stars exploding at a rate of about three per century can account for a large portion, if not all, of the observed interstellar Al-26. In a separate argument using models of Galactic chemical evolution, Clayton (1984) showed that the Al-26/Al-27 production ratio was not large enough to maintain enough Al-26 in the Galactic disk gas of about 10 exp 10 solar masses having solar composition. We present a resolution of those conflicting arguments. A past history of Galactic infall growing the Galactic disk so dilutes the stable Al-27 concentration that the two approaches can be brought into near agreement. If massive stars dominate the production of Al-26, we suggest that the apparent shortfall of their Al-26/Al-27 yield ratio is to be interpreted as evidence for significant growth of the Galactic disk. We also discuss the implications of these arguments for other extinct radioactivities in meteorites, using I-129 and Sm-146 as examples.

  10. Law of substitution for mixed arrays

    International Nuclear Information System (INIS)

    Koudelka, A.J.


    The nuclear safety justification of a mixed array of dissimilar fissile units of metal units and dilute solution units, according to Clayton, has been a persistent and nagging problem. Dissimilar uranium metal or dissimilar uranium solution units in a mixed array can also create a modeling nightmare for the nuclear criticality safety engineer. Now, a calculational method known as the Law of Substitution has been developed to ensure that the k/sub eff/ of an array of uranium metal and uranium solution units will satisfy any k/sub eff/ limit set by the nuclear safety engineer. The nuclear criticality safety engineer can utilize the Law of Substitution to safely mix or substitute different uranium metal units, different uranium solution units, and more importantly, uranium metal and dilute UO 2 solution units in an array. The Law of Substitution is as follows: (1) calculate the k/sub eff/ of each unit type in its own infinite planar array. (2) Determine the edge-to-edge spacing of the infinite planar array of each type of unit to satisfy a desired k/sub eff/. (3) Select the largest edge-to-edge spacing from among the similar units in their infinite planar arrays and use that spacing for the finite or infinite planar array of mixed units

  11. U.S. subprime financial crisis contagion on BRIC and European Union stock markets

    Directory of Open Access Journals (Sweden)

    Daniel Reed Bergmann


    Full Text Available ABSTRACT The Copula Theory was used to analyze contagion among the BRIC (Brazil, Russia, India and China and European Union stock markets with the U.S. Equity Market. The market indexes used for the period between January 01, 2005 and February 27, 2010 are: MXBRIC (BRIC, MXEU (European Union and MXUS (United States. This article evaluated the adequacy of the main copulas found in the financial literature using log-likelihood, Akaike information and Bayesian information criteria. This article provides a groundbreaking study in the area of contagion due to the use of conditional copulas, allowing to calculate the correlation increase between indexes with non-parametric approach. The conditional Symmetrized Joe-Clayton copula was the one that fitted better to the considered pairs of returns. Results indicate evidence of contagion effect in both markets, European Union and BRIC members, with a 5% significance level. Furthermore, there is also evidence that the contagion of U.S. financial crisis was more pronounced in the European Union than in the BRIC markets, with a 5% significance level. Therefore, stock portfolios formed by equities from the BRIC countries were able to offer greater protection during the subprime crisis. The results are aligned with recent papers that present an increase in correlation between stock markets, especially in bear markets.

  12. Thermal maturity patterns in Pennsylvanian coal-bearing rocks in Alabama, Tennessee, Kentucky, Virginia, West Virginia, Ohio, Maryland, and Pennsylvania: Chapter F.2 in Coal and petroleum resources in the Appalachian basin: distribution, geologic framework, and geochemical character (United States)

    Ruppert, Leslie F.; Trippi, Michael H.; Hower, James C.; Grady, William C.; Levine, Jeffrey R.; Ruppert, Leslie F.; Ryder, Robert T.


    Thermal maturation patterns of Pennsylvanian strata in the Appalachian basin and part of the Black Warrior basin were determined by compiling previously published and unpublished percent-vitrinite-reflectance (%R0) measurements and preparing isograd maps on the basis of the measurements. The isograd values range from 0.6 %R0 in Ohio and the western side of the Eastern Kentucky coal field to 5.5 %R0 in the Southern field in the Pennsylvania Anthracite region, Schuylkill County, Pa. The vitrinite-reflectance values correspond to the American Society of Testing Materials (ASTM) coal-rank classes of high-volatile C bituminous to meta-anthracite, respectively. In general, the isograds show that thermal maturity patterns of Pennsylvanian coals within the Appalachian basin generally decrease from east to west. In the Black Warrior basin of Alabama, the isograds show a circular pattern with the highest values (greater than 1.6 %R0) centered in Jefferson County, Ala. Most of the observed patterns can be explained by variations in the depth of burial, variations in geothermal gradient, or a combination of both; however, there are at least four areas of higher ranking coal in the Appalachian basin that are difficult to explain by these two processes alone: (1) a set of west- to northwest-trending salients centered in Somerset, Cambria, and Fayette Counties, Pa.; (2) an elliptically shaped, northeast-trending area centered in southern West Virginia and western Virginia; (3) the Pennsylvania Anthracite region in eastern Pennsylvania; and (4) the eastern part of the Black Warrior coal field in Alabama. The areas of high-ranking coal in southwestern Pennsylvania, the Black Warrior coal field, and the Pennsylvania Anthracite region are interpreted here to represent areas of higher paleo-heat flow related to syntectonic movement of hot fluids towards the foreland associated with Alleghanian deformation. In addition to the higher heat flow from these fluids, the Pennsylvania

  13. Interactive terrain visualization enables virtual field work during rapid scientific response to the 2010 Haiti earthquake (United States)

    Cowgill, Eric; Bernardin, Tony S.; Oskin, Michael E.; Bowles, Christopher; Yikilmaz, M. Burak; Kreylos, Oliver; Elliott, Austin J.; Bishop, Scott; Gold, Ryan D.; Morelan, Alexander; Bawden, Gerald W.; Hamann, Bernd; Kellogg, Louise


    The moment magnitude (Mw) 7.0 12 January 2010 Haiti earthquake is the first major earthquake for which a large-footprint LiDAR (light detection and ranging) survey was acquired within several weeks of the event. Here, we describe the use of virtual reality data visualization to analyze massive amounts (67 GB on disk) of multiresolution terrain data during the rapid scientific response to a major natural disaster. In particular, we describe a method for conducting virtual field work using both desktop computers and a 4-sided, 22 m3 CAVE immersive virtual reality environment, along with KeckCAVES (Keck Center for Active Visualization in the Earth Sciences) software tools LiDAR Viewer, to analyze LiDAR point-cloud data, and Crusta, for 2.5 dimensional surficial geologic mapping on a bare-earth digital elevation model. This system enabled virtual field work that yielded remote observations of the topographic expression of active faulting within an ∼75-km-long section of the eastern Enriquillo–Plantain Garden fault spanning the 2010 epicenter. Virtual field observations indicated that the geomorphic evidence of active faulting and ancient surface rupture varies along strike. Landform offsets of 6–50 m along the Enriquillo–Plantain Garden fault east of the 2010 epicenter and closest to Port-au-Prince attest to repeated recent surface-rupturing earthquakes there. In the west, the fault trace is well defined by displaced landforms, but it is not as clear as in the east. The 2010 epicenter is within a transition zone between these sections that extends from Grand Goâve in the west to Fayette in the east. Within this transition, between L'Acul (lat 72°40′W) and the Rouillone River (lat 72°35′W), the Enriquillo–Plantain Garden fault is undefined along an embayed low-relief range front, with little evidence of recent surface rupture. Based on the geometry of the eastern and western faults that show evidence of recent surface rupture, we propose that the 2010

  14. Book Reviews

    Directory of Open Access Journals (Sweden)

    Lynn Pan


    horizon; Short stories from contemporary Indonesia. Clayton, Victoria: Monash Asia Institute, 1998, xxxviii + 201 pp. - John N. Miksic, Helena A. van Bemmel, Dvarapalas in Indonesia; Temple guardians and acculturation, 1994, xvii + 249 pp. Rotterdam: Balkema. [Modern Quarternary Research in Southeast Asia 13.] - Remco Raben, Paul van Beckum, Adoe Den Haag; Getuigessen uit Indisch Den Haag. Den Haag: SeaPress, 1998, 200 pp. - Cornelia M.J. van der Sluys, Colin Nicholas, Pathway to dependence; Commodity relations and the dissolution of Semai society. Clayton: Centre of Southeast Asian Studies, Monash University, 1994, vii + 130 pp. [Monash Papers on Southeast Asia 33.] - David Stuart-Fox, Herman C. Kemp, Bibliographies on Southeast Asia. Leiden: KITLV Press, 1998, xvii + 1128 pp. - Sikko Visscher, Lynn Pan, The encyclopedia of the Chinese overseas. Richmond, Surrey: Curzon, 1999, 399 pp. - Sikko Visscher, Jurgen Rudolph, Reconstructing identities; A social history of the Babas in Singapore. Aldershot: Ashgate, 1998, 507 pp. - Edwin Wieringa, Perry Moree, ‘Met vriend die God geleide’; Het Nederlands-Aziatisch postvervoer ten tijde van de Verenigde Oost-Indische Compagnie. Zutphen: Walburg Pers, 1998, 287 pp. - Edwin Wieringa, Monique Zaini-Lajoubert, L’image de la femme dans les littératures modernes indonésienne et malaise. Paris: Association Archipel, 1994, ix + 221 pp. [Cahiers d‘Archipel 24.

  15. Book Reviews

    Directory of Open Access Journals (Sweden)

    Raymond L. Bryant


    Full Text Available - R.H. Barnes, Janet Hoskins, Biographical objects; How things tell the stories of people’s lives. London: Routledge, 1998, x + 213 pp. - Peter Boomgaard, Ann Kumar, Java and modern Europe; Ambiguous encounters. Richmond, Surrey: Curzon, 1997, vii + 472 pp. - Peter Boomgaard, Lenore Manderson, Sickness and the state; Health and illness in colonial Malaya, 1870-1940. Cambridge: Cambridge University Press, 1996, xix + 315 pp. - Matthew Isaac Cohen, Bambang Widoyo, Gapit; 4 naskah drama berbahasa Jawa: Rol, Leng, Tuk dan Dom. Yogyakarta: Yayasan Benteng Budaya, 1998, xiv + 302 pp. - James T. Collins, Bernd Nothofer, Reconstruction, classification, description; Festschrift in honor of Isidore Dyen. Hamburg: Abera, 1996, xiv + 259 pp. - J.R. Flenley, Kristina R.M. Beuning, Modern pollen rain, vegetation and climate in lowland East Java, Indonesia. Rotterdam: Balkema, 1996, 51 pp. + 49 plates. [Modern Quaternary Research in Southeast Asia 14.] - Gregory Forth, Karl-Heinze Kohl, Der Tod der Riesjungfrau; Mythen, Kulte und Allianzen in einer ostindonesischen Lokalkultur. Stuttgart: Kohlhammer, 1998, 304 pp. [Religionsethnologische Studien des Frobenius-Instituts Frankfurt am Main, Band I.] - J. van Goor, Brook Barrington, Empires, imperialism and Southeast Asia; Essays in honour of Nicholas Tarling. Clayton, Victoria: Monash Asia Institute, 1997, v + 250 pp. [Monash Papers on Southeast Asia 43.] - Mies Grijns, Penny van Esterik, Women of Southeast Asia. DeKalb: Center for Southeast Asian Studies, Northern Illinois University, 1996, xiv + 229 pp. ‘Monographs on Southeast Asia, Occasional Paper 17; Second, revised edition.] - Hans Hagerdal, Alfons van der Kraan, Bali at war; A history of the Dutch-Balinese conflict of 1846-49. Clayton, Victoria: Centre of Southeast Asian Studies, Monash University, 1995, x + 240 pp. [Monash Papers on Southeast Asia 34]. - Volker Heeschen, Jurg Wassmann, Das Ideal des leicht gebeugten Menschen; Eine ethnokognitive

  16. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV


    Full Text Available -Barbara Watson Andaya, Susan Blackburn, Love, sex and power; Women in Southeast Asia. Clayton VIC: Monash Asia Institute, 2001, iv + 144 pp. [Monash papers on Southeast Asia 55.] -Kathryn Gay Anderson, Juliette Koning ,Women and households in Indonesia; Cultural notions and social practices. Richmond, Surrey: Curzon, 2000, xiii + 354 pp. [Nordic Institute of Asian studies, studies in Asian topics 27.], Marleen Nolten, Janet Rodenburg (eds -Greg Bankoff, Takeshi Kawanaka, Power in a Philippine city. Chiba: Institute of developing economies, 2002, 118 pp. [IDE Occasional papers series 38.] -René van den Berg, John Lynch ,The Oceanic languages. Richmond, Surrey: Curzon, 2002, xvii + 924 pp., Malcolm Ross, Terry Crowley (eds -H.J.M. Claessen, Douglas Oliver, Polynesia in early historic times. Honolulu: Bess Press, 2002, 305 pp. -Harold Crouch, Andrew Rosser, The politics of economic liberalisation in Indonesia; State, market and power. Richmond, Surrey: Curzon, 2002, xv + 232 pp. -Hans Hägerdal, Arend de Roever, De jacht op sandelhout; De VOC en de tweedeling van Timor in de zeventiende eeuw. Zutphen: Walburg Pers, 2002, 383 pp. -Fiona Harris, Lorraine V. Aragon ,Structuralism's transformations; Order and revision in Indonesian and Malaysian societies; Paper written in honor of Clark E. Cunningham. Tempe AZ: Arizona State University Press, 1999, lxii + 402 pp., Susan D. Russell (eds -David Henley, Christiaan Heersink, Dependence on green gold: A socio-economic history of the Indonesian coconut island Selayar. Leiden: KITlV Press, 1999, xviii + 371 pp. [Verhandelingen 184.] -David Hicks, James T. Siegel ,Southeast Asia over three generations; Essays presented to Benedict R.O'G. Anderson 2003, 398 pp. Ithaca NY: Cornell University Southeast Asia program. [Studies on Southeast Asia 36.], Audrey R. Kahin (eds -Janny de Jong, L. de Jong, The collapse of a colonial society; The Dutch in Indonesia during the second world war. With an introduction by

  17. Hydrologic conditions, groundwater quality, and analysis of sink hole formation in the Albany area of Dougherty County, Georgia, 2009 (United States)

    Gordon, Debbie W.; Painter, Jaime A.; McCranie, John M.


    The U.S. Geological Survey, in cooperation with the Albany Water, Gas, and Light Commission has conducted water resources investigations and monitored groundwater conditions and availability in the Albany, Georgia, area since 1977. This report presents an overview of hydrologic conditions, water quality, and groundwater studies in the Albany area of Dougherty County, Georgia, during 2009. Historical data also are presented for comparison with 2009 data. During 2009, groundwater-level data were collected in 29 wells in the Albany area to monitor water-level trends in the surficial, Upper Floridan, Claiborne, Clayton, and Providence aquifers. Groundwater-level data from 21 of the 29 wells indicated an increasing trend during 2008–09. Five wells show no trend due to lack of data and three wells have decreasing trends. Period-of-record water levels (period of record ranged between 1957–2009 and 2003–2009) declined slightly in 10 wells and increased slightly in 4 wells tapping the Upper Floridan aquifer; declined in 1 well and increased in 2 wells tapping the Claiborne aquifer; declined in 4 wells and increased in 2 wells tapping the Clayton aquifer; and increased in 1 well tapping the Providence aquifer. Analyses of groundwater samples collected during 2009 from 12 wells in the Upper Floridan aquifer in the vicinity of a well field located southwest of Albany indicate that overall concentrations of nitrate plus nitrite as nitrogen increased slightly from 2008 in 8 wells. A maximum concentration of 12.9 milligrams per liter was found in a groundwater sample from a well located upgradient from the well field. The distinct difference in chemical constituents of water samples collected from the Flint River and samples collected from wells located in the well-field area southwest of Albany indicates that little water exchange occurs between the Upper Floridan aquifer and Flint River where the river flows adjacent to, but downgradient of, the well field. Water

  18. A Diverging View of Role Modeling in Medical Education

    Directory of Open Access Journals (Sweden)

    Gurjit Sandhu


    Full Text Available Research in the area of role modeling has primarily focused on the qualities and attributes of exceptional role models, and less attention has been given to the act of role modeling itself (Elzubeir & Rizk, 2001; Jochemsen-van der Leeuw, van Dijk, van Etten-Jamaludin, & Wieringa-de Waard, 2013; Wright, 1996; Wright, Wong, & Newill, 1997. A standardized understanding of role modeling in medical education remains elusive (Kenny, Mann, & MacLeod, 2003. This is problematic given that role modeling is pervasively documented as an approach to teaching (Reuler & Nardone, 1994. Our study attempts to fill a void in this body of research by looking at what faculty are thinking, saying, and doing when they say they are role modeling. Individual semi-structured interviews with faculty members were conducted in the Department of General Surgery at Queen’s University, Kingston, Ontario, Canada. Interviews were recorded, transcribed, and analyzed using qualitative methods for themes surrounding teaching and role modeling. Three major themes emerged from the data: (1 faculty members think they are teaching when they are acting professionally; (2 faculty members become aware of teaching opportunities and act on them; and (3 faculty members employ evidence-based teaching methods, but they are incorrectly labeling them as “role modeling.” As a whole, our findings should help distinguish between role modeling as roles and responsibilities enacted while doing one’s job well, and teaching as facilitated instruction that helps connect knowledge with action (Clayton, 2006; Fassbinder, 2007. Contributing to a better understanding of how teaching is separate from role modeling has the potential to improve the scope and quality of teaching, ultimately enhancing the learning experience for trainees.

  19. 2012 international year for sustainable energy for all: African Frontrunnership in rural electrification

    International Nuclear Information System (INIS)

    Mahama, Amadu


    2012 has been declared the “International Year for Sustainable Energy for All” by the UN. While Africa remains the most ‘underpowered’ continent, the prognosis for a brighter future is looking good, as key stakeholders (governments, private sector, civil society, and the donor community) have mobilized at an unprecedented scale to experiment with new policies, regulatory frameworks, and business models to rapidly upscale access to sustainable energy. The top-down, central grid expansion approach to increasing electricity access is very capital intensive and yet has gained considerable momentum at the expense of lower cost options that utilize decentralized off-grid solutions. A decentralized bottom-up approach could also use indigenous renewable energy sources and foster more significant linkages with livelihood opportunities in the rural un-served territories. This paper evaluates the emerging experiments through the lenses of C.K. Prahalad's “bottom of the pyramid” theory and Clayton Christensen's “disruptive technologies” perspective. Three front-runner initiatives involving new business models, innovative technologies, and institutional capacity building will be analyzed. In addition, the paper examines a regulatory policy initiative designed to stimulate clean energy investments in Ghana. Though the examples are all from Ghana, they illustrate general challenges to sub-Saharan Africa as a whole. - Highlights: ► An analysis of innovative electricity access case studies from Ghana. ► Off-grid electrification options are keys to expanding electricity access in Africa. ► Base of the pyramid strategies for rural electrification has a niche in Africa. ► International collaboration will be crucial to achieve universal electricity access.

  20. 2D spectral element modeling of GPR wave propagation in inhomogeneous media (United States)

    Zarei, Sajad; Oskooi, Behrooz; Amini, Navid; Dalkhani, Amin Rahimi


    We present a spectral element method, for simulation of ground-penetrating radar (GPR) in two dimensions. The technique is based upon a weak formulation of the equations of Maxwell and combines the flexibility of the elemental-based methods with the accuracy of the spectral based methods. The wave field on the elements is discretized using high-degree Lagrange interpolation and integration over an element is accomplished based upon the Gauss-Lobatto-Legendre integration rule. As a result, the mass matrix and the damping matrix are always diagonal, which drastically reduces the computational cost. We first develop the formulation of 2D spectral element method (SEM) in the time-domain based on Maxwell's equations. The presented formulation is with matrix notation that simplifies the implementation of the relations in computer programs, especially in MATLAB application. We discuss the differences between spectral element method and finite-element method in the time-domain. Also, we show that the SEM numerical dispersion is much lower than FEM. To absorb waves at the edges of the modeling domain, we implement first order Clayton and Engquist absorbing boundary conditions (CE-ABC) introduced in numerical finite-difference modeling of seismic wave propagation. We used the SEM to simulate a complex model to show its abilities and limitations. As well as, one distinct advantage of SEM is that we can easily define our model features in nodal points, because the integration points and the interpolation points are similar that makes it very flexible in simulation of complex models.

  1. Phosphoric acid purification through different raw and activated clay materials (Southern Tunisia) (United States)

    Trabelsi, Wafa; Tlili, Ali


    This study concerns the purification of Tunisian phosphoric acid produced by the Tunisian Chemical Group (TCG), using raw and activated clays materials from Southern Tunisia. The Gafsa basin clays samples (Jebel Hamadi (JHM); Jebel Stah (JS) and the El Hamma sample (Jebel Aïdoudi (JAD)) were activated with 3 M, HCl solution. Phosphoric acid purification was performed on raw and activated clays. Mineralogical characterisation was carried out using the X-ray powder diffraction method and infrared absorption spectroscopy. Textural changes between raw and activated clays were identified using SEM observations and specific surface analysis. Jebel Hamadi clays were almost dominated by smectite associated with kaolinite and illite traces, while Jebel Stah and Jebel Aïdoudi clays were composed of the association of smectite, illite and kaolinite. It is worth noting that the position of the smectite (001) reflection increased after the acidic activation in all studied samples, indicating the relaxation of the smectite structure along the c-axis. This was corroborated by the increasing specific surface area of the clay particles with the activation process. The specific surface area was close to 50 m2/g and 200 m2/g, for raw and activated materials, respectively. The maximum phosphoric acid purification was obtained by using activated clays with 3 N HCl for 4 h. This performance correlated with the maximum of the external specific surface area which generated strong acid sites. Furthermore, the best results of phosphoric acids purification from TCG were obtained at a specific consumption equivalent to 30 Kg of clay/ton of P2O5. These results showed that the best phosphoric acid purification was yielded by Jebel Aïdoudi clay. In all cases, the highest organic carbon reduction rates in the phosphoric acid after filtration were obtained at 90°C.

  2. Cultivating Bakhtin in the garden: Children's ecological narratives on becoming community gardeners (United States)

    Grugel, Annie H.


    This dissertation illustrates how a children's community garden, designed specifically to promote intergenerational, multi-sociocultural relationships, is an "ideological environment" linking individuals and their community and connecting people with nature, in order to promote feelings of belonging, social connection, and encourage a sense of stewardship and identification with the environment (Bakhtin, 1978). By spending time in a community garden, responding to the natural ecosystems which exist on this land, and reflecting, through image and story about our childhood experience, the participants and I engaged in the dialogic process of what Thomashow (1996) refers to as "doing ecological identity work." Throughout this study I question how our past experiences with nature in ideological environments shape our ecological epistemologies, and how the dialogic process of becoming a gardener within the context of a community garden shapes a person's ecological identity. To frame this exploration of ecological identity work as a dialogic process and its role in the development of an ecological identity, I draw from sociocultural theory (Holland, et al., 1998), Bakhtin's theory of dialogism, and ecological identity studies (Clayton and Opotow, 2003; Cobb, 1993; Orr, 1994, 2006; Sobel, 1996, 2008; Thomashow, 1996). A large body of scholarly writing done by environmental researchers is devoted to examining and describing how adults, who self-identify as environmentalists, developed an ecological worldview. However, only a fraction of research is devoted to theorizing how children develop an environmental epistemology. In this study, I focus on how community gardens are dialogic spaces that provide a place for elementary-aged children to "experience" the discourse of gardening. Here, I describe the discourses that shape the garden and describe how gardeners, as a result of their collaborative experiences between human and non-human actors, take up social and dialogical

  3. Ultra-pure, water-dispersed Au nanoparticles produced by femtosecond laser ablation and fragmentation

    Directory of Open Access Journals (Sweden)

    Kubiliūtė R


    Full Text Available Reda Kubiliūtė,1,2 Ksenia A Maximova,3 Alireza Lajevardipour,1 Jiawey Yong,1 Jennifer S Hartley,1 Abu SM Mohsin,1 Pierre Blandin,3 James WM Chon,1 Marc Sentis,3 Paul R Stoddart,1 Andrei Kabashin,3 Ričardas Rotomskis,2 Andrew HA Clayton,1,4 Saulius Juodkazis1,4 1Centre for Micro-Photonics and Industrial Research Institute Swinburne, Faculty of Engineering and Industrial Sciences Swinburne University of Technology, Hawthorn, VIC, Australia; 2Laboratory of Biomedical Physics, Vilnius University Institute of Oncology, Baublio, Vilnius, Lithuania; 3Aix-Marseille University, Centre National de la Recherche Scientifique (CNRS, Lasers, Plasmas and Photonics Processing Laboratory, Campus de Luminy, Marseille, France; 4The Australian National Fabrication Facility, Victoria node, Faculty of Engineering and Industrial Sciences, Swinburne University of Technology, Hawthorn, VIC, Australia Abstract: Aqueous solutions of ultra-pure gold nanoparticles have been prepared by methods of femtosecond laser ablation from a solid target and fragmentation from already formed colloids. Despite the absence of protecting ligands, the solutions could be (1 fairly stable and poly size-dispersed; or (2 very stable and monodispersed, for the two fabrication modalities, respectively. Fluorescence quenching behavior and its intricacies were revealed by fluorescence lifetime imaging microscopy in rhodamine 6G water solution. We show that surface-enhanced Raman scattering of rhodamine 6G on gold nanoparticles can be detected with high fidelity down to micromolar concentrations using the nanoparticles. Application potential of pure gold nanoparticles with polydispersed and nearly monodispersed size distributions are discussed. Keywords: nanotechnologies applications, methods of nanofabrication and processing, materials for nanomedicine

  4. Conduits to care: call lights and patients’ perceptions of communication

    Directory of Open Access Journals (Sweden)

    Montie M


    Full Text Available Mary Montie,1 Clayton Shuman,1 Jose Galinato,1 Lance Patak,2 Christine A Anderson,1 Marita G Titler1 1Department of Systems, Populations, and Leadership, School of Nursing, University of Michigan, Ann Arbor, MI, 2Department of Anesthesiology and Pain Medicine, Seattle Children’s Hospital, Seattle, WA, USA Background: Call light systems remain the primary means of hospitalized patients to initiate communication with their health care providers. Although there is vast amounts of literature discussing patient communication with their health care providers, few studies have explored patients’ perceptions concerning call light use and communication. The specific aim of this study was to solicit patients’ perceptions regarding their call light use and communication with nursing staff. Methods: Patients invited to this study met the following inclusion criteria: proficient in English, been hospitalized for at least 24 hours, aged ≥21 years, and able to communicate verbally (eg, not intubated. Thirty participants provided written informed consent, were enrolled in the study, and completed interviews. Results: Using qualitative descriptive methods, five major themes emerged from patients’ perceptions (namely; establishing connectivity, participant safety concerns, no separation: health care and the call light device, issues with the current call light, and participants’ perceptions of “nurse work”. Multiple minor themes supported these major themes. Data analysis utilized the constant comparative methods of Glaser and Strauss. Discussion: Findings from this study extend the knowledge of patients’ understanding of not only why inconsistencies occur between the call light and their nurses, but also why the call light is more than merely a device to initiate communication; rather, it is a direct conduit to their health care and its delivery. Keywords: nurse–patient communication, medical technology, quality of care, qualitative research

  5. Mapping your innovation strategy. (United States)

    Anthony, Scott D; Eyring, Matt; Gibson, Lib


    In the complex sport of American football, teams rely on playbooks as thick as the Manhattan phone directory. But when it comes to creating innovative growth businesses-which is at least as complicated as professional football--most companies have not developed detailed game plans. Indeed, many managers have concluded that a fog enshrouds the world of innovation, obscuring high-potential opportunities. The authors believe that companies can penetrate that fog by developing growth strategies based on disruptive innovations, as defined by Clayton Christensen. Such innovations conform to a pattern: They offer an entirely new solution; they perform adequately along traditional dimensions and much better along other dimensions that matter more to target customers; and they are not initially appealing to powerful incumbents. Companies can develop customized checklists, or playbooks, by combining this basic pattern with analysis of major innovations in their markets. The key early on is to focus not on detailed financial estimates--which will always guide companies toward the markets most hostile to disruptive innovations--but on how well the innovation fits the pattern of success. It's also crucial to encourage flexibility: Companies must be willing to kill projects that are going nowhere, exempt innovations from standard development processes, and avoid burdening project teams with extra financing, which can keep them heading in the wrong direction. Companies can create competitive advantage by becoming champions at defining the pattern of successful innovations and executing against it. But as that pattern becomes obvious--and others emerge-building a sustainable advantage on innovation competencies will again prove elusive.

  6. Efecto de tipos de labranza sobre la población de malezas en caña de azúcar

    Directory of Open Access Journals (Sweden)

    Ram\\u00F3n Le\\u00F3n


    Full Text Available En dos lotes de caña de azúcar, uno con baja presión de malezas (lote 1 y otro con alta (lote 2, se evaluaron cuatro tratamientos: cosecha en verde con rastrojo (VCR, cosecha en verde sin rastrojo (VSR, cosecha con quema sin labranza (QSL y cosecha con quema con labranza (QCL. Se evaluó las especies de malezas así como su población y cobertura del suelo hasta los 75 días después de cosecha, tanto en el surco como en el entre-surco. Además, se evaluó la altura y el número de tallos del cultivo por metro lineal. No se observaron diferencias entre las poblaciones de malezas en el lote 1. En el lote 2 las malezas se vieron beneficiadas por la labranza y por la quema; así los tratamientos QSL y QCL mostraron las mayores coberturas, siendo este último el que presentó las poblaciones más altas y en el que se dió una disminución en el número y altura de tallos de la caña de azúcar. Cyperus rotundus L. y Rottboellia cochinchinensis (Lour Clayton presentaron las mayores coberturas, especialmente en QCL. En el surco se dio un desarrollo superior de las poblaciones de malezas, al observado en el entre-surco, ya que presentó mejores condiciones de germinación y disponibilidad de nutrimentos

  7. Developing critical thinking, creativity and innovation skills of undergraduate students (United States)

    Shoop, Barry L.


    A desirable goal of engineering education is to teach students how to be creative and innovative. However, the speed of technological innovation and the continual expansion of disciplinary knowledge leave little time in the curriculum for students to formally study innovation. At West Point we have developed a novel upper-division undergraduate course that develops the critical thinking, creativity and innovation of undergraduate science and engineering students. This course is structured as a deliberate interactive engagement between students and faculty that employs the Socratic method to develop an understanding of disruptive and innovative technologies and a historical context of how social, cultural, and religious factors impact the acceptance or rejection of technological innovation. The course begins by developing the background understanding of what disruptive technology is and a historical context about successes and failures of social, cultural, and religious acceptance of technological innovation. To develop this framework, students read The Innovator's Dilemma by Clayton M. Christensen, The Structure of Scientific Revolutions by Thomas S. Kuhn, The Discoverers by Daniel J. Boorstin, and The Two Cultures by C.P. Snow. For each class meeting, students survey current scientific and technical literature and come prepared to discuss current events related to technological innovation. Each student researches potential disruptive technologies and prepares a compelling argument of why the specific technologies are disruptive so they can defend their choice and rationale. During course meetings students discuss the readings and specific technologies found during their independent research. As part of this research, each student has the opportunity to interview forward thinking technology leaders in their respective fields of interest. In this paper we will describe the course and highlight the results from teaching this course over the past five years.

  8. Implementation of evidence-based stroke care: enablers, barriers, and the role of facilitators

    Directory of Open Access Journals (Sweden)

    Purvis T


    Full Text Available Tara Purvis,1,2 Karen Moss,2 Sonia Denisenko,3 Chris Bladin,2,5 Dominique A Cadilhac1,2,4 1Translational Public Health Unit, Stroke and Ageing Research Centre, Department of Medicine, Monash Medical Centre, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia; 2Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne Brain Centre, Heidelberg, VIC, Australia; 3Commission for Hospital Improvement, Department of Health Victoria, VIC, Australia; 4Department of Medicine, University of Melbourne, Parkville, VIC, Australia; 5Eastern Health Clinical School, Monash University, Box Hill, VIC, Australia Abstract: A stroke care strategy was developed in 2007 to improve stroke services in Victoria, Australia. Eight stroke network facilitators (SNFs were appointed in selected hospitals to enable the establishment of stroke units, develop thrombolysis services, and implement protocols. We aimed to explain the main issues being faced by clinicians in providing evidence-based stroke care, and to determine if the appointment of an SNF was perceived as an acceptable strategy to improve stroke care. Face-to-face semistructured interviews were used in a qualitative research design. Interview transcripts were verified by respondents prior to coding. Two researchers conducted thematic analysis of major themes and subthemes. Overall, 84 hospital staff participated in 33 interviews during 2008. The common factors found to impact on stroke care included staff and equipment availability, location of care, inconsistent use of clinical pathways, and professional beliefs. Other barriers included limited access to specialist clinicians and workload demands. The establishment of dedicated stroke units was considered essential to improve the quality of care. The SNF role was valued for identifying gaps in care and providing capacity to change clinical processes. This is the first large, qualitative multicenter study to

  9. Análise dos co-movimentos entre os mercados de capitais do Brasil e dos EUA

    Directory of Open Access Journals (Sweden)

    Daniel Reed Bergmann


    Full Text Available Neste artigo, a teoria de cópulas é utilizada para analisar os co-movimentos entre os mercados de capitais do Brasil e dos EUA. Na finalidade de implementação de uma estratégia de alocação de ativos é importante entender os eventos extremos - tanto os positivos (boom como os negativos (crashes - e seus efeitos sobre os mercados. Os índices de mercado usados são o IBOVESPA e o S&P 500 cobrindo o período de 03/2001 a 04/2007. A aderência aos log-retornos das principais cópulas encontradas na literatura financeira é avaliada. Os seguintes critérios foram escolhidos: o Log-likelihod, o critério de informação de Akaike e o critério de informação bayesiano. Os resultados mostram que a cópula de Joe-Clayton simetrizada é a mais adequada para modelar a estrutura de dependência entre os log-retornos do IBOVESPA e os do S&P500. Este trabalho difere de alguns estudos já realizados [e.g. Mendes e Moretti(2005 e Canela e Collazo(2005], pois leva em consideração a modelagem de cópulas dinâmicas introduzida por Patton (2006. Finalmente, através dos índices de dependência caudal ao longo do tempo, pode-se concluir que a ocorrência de eventos extremos negativos (crashes no mercado norte americano tende a afetar mais o mercado brasileiro quando da comparação da ocorrência dos eventos extremos positivos (booms.

  10. Joint modelling of flood peaks and volumes: A copula application for the Danube River

    Directory of Open Access Journals (Sweden)

    Papaioannou George


    Full Text Available Flood frequency analysis is usually performed as a univariate analysis of flood peaks using a suitable theoretical probability distribution of the annual maximum flood peaks or peak over threshold values. However, other flood attributes, such as flood volume and duration, are necessary for the design of hydrotechnical projects, too. In this study, the suitability of various copula families for a bivariate analysis of peak discharges and flood volumes has been tested. Streamflow data from selected gauging stations along the whole Danube River have been used. Kendall’s rank correlation coefficient (tau quantifies the dependence between flood peak discharge and flood volume settings. The methodology is applied to two different data samples: 1 annual maximum flood (AMF peaks combined with annual maximum flow volumes of fixed durations at 5, 10, 15, 20, 25, 30 and 60 days, respectively (which can be regarded as a regime analysis of the dependence between the extremes of both variables in a given year, and 2 annual maximum flood (AMF peaks with corresponding flood volumes (which is a typical choice for engineering studies. The bivariate modelling of the extracted peak discharge - flood volume couples is achieved with the use of the Ali-Mikhail-Haq (AMH, Clayton, Frank, Joe, Gumbel, Hüsler-Reiss, Galambos, Tawn, Normal, Plackett and FGM copula families. Scatterplots of the observed and simulated peak discharge - flood volume pairs and goodness-of-fit tests have been used to assess the overall applicability of the copulas as well as observing any changes in suitable models along the Danube River. The results indicate that for the second data sampling method, almost all of the considered Archimedean class copula families perform better than the other copula families selected for this study, and that for the first method, only the upper-tail-flat copulas excel (except for the AMH copula due to its inability to model stronger relationships.

  11. Structural and functional diversity of free-living microorganisms in reef surface, Kra island, Thailand. (United States)

    Somboonna, Naraporn; Wilantho, Alisa; Assawamakin, Anunchai; Monanunsap, Somchai; Sangsrakru, Duangjai; Tangphatsornruang, Sithichoke; Tongsima, Sissades


    Coral reefs worldwide are being harmed through anthropogenic activities. Some coral reefs in Thailand remain well-preserved, including the shallow coral reefs along Kra island, Nakhon Si Thammarat province. Interestingly, the microbial community in this environment remains unknown. The present study identified biodiversity of prokaryotes and eukaryotes of 0.22-30 μm in sizes and their metabolic potentials in this coral reef surface in summer and winter seasons, using 16S and 18S rRNA genes pyrosequencing. The marine microbial profiles in summer and winter seasons comprised mainly of bacteria, in phylum, particular the Proteobacteria. Yet, different bacterial and eukaryotic structures existed between summer and winter seasons, supported by low Lennon and Yue & Clayton theta similarity indices (8.48-10.43% for 16S rRNA, 0.32-7.81% for 18S rRNA ). The topmost prokaryotic phylum for the summer was Proteobacteria (99.68%), while for the winter Proteobacteria (62.49%) and Bacteroidetes (35.88%) were the most prevalent. Uncultured bacteria in phyla Cyanobacteria, Planctomycetes, SAR406 and SBR1093 were absent in the summer. For eukaryotic profiles, species belonging to animals predominated in the summer, correlating with high animal activities in the summer, whereas dormancy and sporulation predominated in the winter. For the winter, eukaryotic plant species predominated and several diverse species were detected. Moreover, comparison of our prokaryotic databases in summer and winter of Kra reef surface against worldwide marine culture-independent prokaryotic databases indicated our databases to most resemblance those of coastal Sichang island, Chonburi province, Thailand, and the 3 tropical GOS sites close to Galapagos island (GS039, GS040 and GS045), in orderly. The study investigated and obtained culture-independent databases for marine prokaryotes and eukaryotes in summer and winter seasons of Kra reef surface. The data helped understand seasonal dynamics of microbial

  12. The role of paliperidone extended release for the treatment of bipolar disorder

    Directory of Open Access Journals (Sweden)

    Marino J


    Full Text Available Jehan Marino1, Clayton English2, Joshua Caballero1, Catherine Harrington11College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL, 2College of Pharmacy, Albany College of Pharmacy and Health Sciences, Colchester, VT, USABackground: Bipolar disorder (BD is a chronic, relapsing, episodic mental illness associated with other psychiatric comorbidities. There is a substantial economic burden with BD, which makes it challenging to treat. The aim of this review is to evaluate the pharmacology, clinical efficacy, and safety data related to paliperidone extended release (ER for the treatment of BD.Methods: A literature search was performed from January 1966 through January 2012 using PreMEDLINE, MEDLINE, EMBASE, IPA, and to identify articles in English regarding the pharmacology, clinical efficacy, and safety of paliperidone ER in acute mania or mixed episodes or in the maintenance treatment of BD I.Results: There are currently three published studies relating to the use of paliperidone ER for the treatment of BD. Two of these evaluated paliperidone ER as monotherapy for acute mania, while the other assessed its role as adjunct with a mood stabilizer.Conclusion: According to the limited available evidence, paliperidone at higher doses of ER 9–12 mg/day may be a safe and efficacious treatment option for acute episodes of mania in BD. A once-daily dose formulation may improve patient adherence to treatment; however, the cost of paliperidone ER, which is higher than that of generically available second-generation antipsychotics (such as olanzapine and risperidone, and a lack of alternative dosage forms (ie, liquid, intramuscular compared with other agents may limit its usefulness in the treatment of BD. The role of paliperidone ER as an adjunctive agent or for long-term use requires further investigation.Keywords: paliperidone ER, bipolar disorder, clinical efficacy, safety

  13. Petrology and chemistry of the basaltic shergottite North West Africa 480 (United States)

    Barrat, J. A.; Gillet, Ph.; Sautter, V.; Jambon, A.; Javoy, M.; Göpel, C.; Lesourd, M.; Keller, F.; Petit, E.


    North West Africa (NWA) 480 is a new martian meteorite of 28 g found in the Moroccan Sahara in November 2000. It consists mainly of large gray pyroxene crystals (the largest grains are up to 5 mm in length) and plagioclase converted to maskelynite. Excluding the melt pocket areas, modal analyses indicate the following mineral proportions: 72 vol% pyroxenes extensively zoned, 25% maskelynite, 1% phosphates (merrillite and chlorapatite), 1% opaque oxides (ilmenite, ulvospinel and chromite) and sulfides, and 1% others such as silica and fayalite. The compositional trend of NWA 480 pyroxenes is similar to that of Queen Alexandra Range (QUE) 94201 but in NWA 480 the pyroxene cores are more Mg-rich (En77-En65). Maskelynites display a limited zoning (An42-50Ab54-48Or2-4). Our observations suggest that NWA 480 formed from a melt with a low nuclei density at a slow cooling rate. The texture was achieved via a single-stage cooling where pyroxenes grew continuously. A similar model was previously proposed for QUE 94201 by McSween et al. (1996). NWA 480 is an Al-poor ferroan basaltic rock and resembles Zagami or Shergotty for major elements and compatible trace element abundances. The bulk rock analysis for oxygen isotopes yields V17O = +0.42%o, a value in agreement at the high margin, with those measured on other shergottites (Clayton and Mayeda, 1996; Romanek et al., 1998; Franchi et al., 1999). Its CI-normalized rare earth element pattern is similar to those of peridotitic shergottites such as Allan Hills (ALH)A77005, suggesting that these shergottites shared a similar parent liquid, or at least the same mantle source.

  14. Discovery of posttranscriptional regulatory RNAs using next generation sequencing technologies. (United States)

    Gelderman, Grant; Contreras, Lydia M


    Next generation sequencing (NGS) has revolutionized the way by which we engineer metabolism by radically altering the path to genome-wide inquiries. This is due to the fact that NGS approaches offer several powerful advantages over traditional methods that include the ability to fully sequence hundreds to thousands of genes in a single experiment and simultaneously detect homozygous and heterozygous deletions, alterations in gene copy number, insertions, translocations, and exome-wide substitutions that include "hot-spot mutations." This chapter describes the use of these technologies as a sequencing technique for transcriptome analysis and discovery of regulatory RNA elements in the context of three main platforms: Illumina HiSeq, 454 pyrosequencing, and SOLiD sequencing. Specifically, this chapter focuses on the use of Illumina HiSeq, since it is the most widely used platform for RNA discovery and transcriptome analysis. Regulatory RNAs have now been found in all branches of life. In bacteria, noncoding small RNAs (sRNAs) are involved in highly sophisticated regulatory circuits that include quorum sensing, carbon metabolism, stress responses, and virulence (Gorke and Vogel, Gene Dev 22:2914-2925, 2008; Gottesman, Trends Genet 21:399-404, 2005; Romby et al., Curr Opin Microbiol 9:229-236, 2006). Further characterization of the underlying regulation of gene expression remains poorly understood given that it is estimated that over 60% of all predicted genes remain hypothetical and the 5' and 3' untranslated regions are unknown for more than 90% of the genes (Siegel et al., Trends Parasitol 27:434-441, 2011). Importantly, manipulation of the posttranscriptional regulation that occurs at the level of RNA stability and export, trans-splicing, polyadenylation, protein translation, and protein stability via untranslated regions (Clayton, EMBO J 21:1881-1888, 2002; Haile and Papadopoulou, Curr Opin Microbiol 10:569-577, 2007) could be highly beneficial to metabolic

  15. Epidemiology of Eimeria species in selected broiler farms of Khoy suburb, West Azarbaijan Province, Iran

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    Fakhri, M.


    Full Text Available Intestinal coccidiosis, caused by Eimeria species, is an economically-important disease of poultry production industry worldwide. This study was designed to investigate the prevalence of different Eimeria species in the farmed broilers of Khoy city, West Azarbaijan, North West Iran. A total of 26 broiler farms of different production capacities were arbitrarily selected and examined in 2013. In each of the farms, Litters of two broilers farms were randomly sampled twice a week and examined. The intensity of infection with each of the Eimeria species was assessed on the basis of number of oocysts per gram of litter using Clayton-Lane and McMaster methods. Eimeria species diversity was determined by using oocyst sporulation technique in 2% potassium dichromate solution. Results indicated that 23.08% (6/26 of the broiler farms were infected with Eimeria oocysts. The maximum litter infection rate (7.5×103 was observed in fifth week of the rearing period. The litter infection rate was significantly correlated with kinds of water dispenser, feeder, ventilation, and density. The litters were infected with five Eimeria species; E. maxima (32.67% in 6 farms (23.07%, E. mitis (24% in 6 farms (23.07%, E. acervulina (18% in 5 farms (19.23%, E. tenella (14.67% in 4 farms (15.38%, and E. necatrix (10.67% in 3 farms (11.58%. Results of this study uncovered high rates of litter infection with various Eimeria species in the studied farms, suggesting the establishment of firm health management strategies in the region.

  16. Break free from the product life cycle. (United States)

    Moon, Youngme


    Most firms build their marketing strategies around the concept of the product life cycle--the idea that after introduction, products inevitably follow a course of growth, maturity, and decline. It doesn't have to be that way, says HBS marketing professor Youngme Moon. By positioning their products in unexpected ways, companies can change how customers mentally categorize them. In doing so, they can shift products lodged in the maturity phase back--and catapult new products forward--into the growth phase. The author describes three positioning strategies that marketers use to shift consumers' thinking. Reverse positioning strips away"sacred" product attributes while adding new ones (JetBlue, for example, withheld the expected first-class seating and in-flight meals on its planes while offering surprising perks like leather seats and extra legroom). Breakaway positioning associates the product with a radically different category (Swatch chose not to associate itself with fine jewelry and instead entered the fashion accessory category). And stealth positioning acclimates leery consumers to a new offering by cloaking the product's true nature (Sony positioned its less-than-perfect household robot as a quirky pet). Clayton Christensen described how new, simple technologies can upend a market. In an analogous way, these positioning strategies can exploit the vulnerability of established categories to new positioning. A company can use these techniques to go on the offensive and transform a category by demolishing its traditional boundaries. Companies that disrupt a category through positioning create a lucrative place to ply their wares--and can leave category incumbents scrambling.

  17. Abortion providers seek to use RICO law as redress for clinic violence. (United States)


    Abortion rights groups pursue multiple avenues for redress against abortion protesters at clinics around the US. The Supreme Court opinion in January 1993 in Bray vs. Alexandria Women's Health Clinic states that the Ku Klux Klan Act may not be used to protect clinics. A federal appeals court opinion states that a provision of the act does provide some protection for clinics. Both the Senate and House of Representatives passed bills making damage to an abortion clinic or intimidation of patients and staff a federal crime. The passage of this legislation into law is expected in early 1994. The case of NOW (the National Organization for Women) vs. Scheidler, initiated in 1986, is not expected to be ruled on until the summer of 1994. Depending upon the ruling, NOW will file another suit in a lower court referring to RICO (Racketeer Influenced and Corrupt Organizations Act) violations and a pattern of criminal activity. NOW's lawyer Fay Clayton puts forth the argument that clinic violence is a "nationwide campaign of terror" designed to halt the practice of abortion and is illegal under RICO. Robert Blakely, one of the original authors of RICO, represents Operation Rescue and the ProLife Action League. RICO was used in the past against mobsters, stock manipulators, and pornographers. Lower courts are inconsistent in the interpretation of whether the economic motive is essential for enforcement of RICO. RICO refers to "affairs" of an "enterprise" engaging in two or more incidents of criminal activity such as extortion, arson, and kidnapping. The Supreme Court criticized Congress for vague wording in the law and for not fulfilling its responsibility to refine the language. Congress has, since 1970, tried to rewrite the law without success. The US Solicitor General, attorney Miguel Estrada, argued that the economic motive requirement limits the role Congress intended for RICO. The administration may use RICO to prosecute terrorists in the World Trade Center bombing and

  18. Comparative efficiency research (COMER): meta-analysis of cost-effectiveness studies. (United States)

    Crespo, Carlos; Monleon, Antonio; Díaz, Walter; Ríos, Martín


    The aim of this study was to create a new meta-analysis method for cost-effectiveness studies using comparative efficiency research (COMER). We built a new score named total incremental net benefit (TINB), with inverse variance weighting of incremental net benefits (INB). This permits determination of whether an alternative is cost-effective, given a specific threshold (TINB > 0 test). Before validation of the model, the structure of dependence between costs and quality-adjusted life years (QoL) was analysed using copula distributions. The goodness-of-fit of a Spanish prospective observational study (n = 498) was analysed using the Independent, Gaussian, T, Gumbel, Clayton, Frank and Placket copulas. Validation was carried out by simulating a copula distribution with log-normal distribution for costs and gamma distribution for disutilities. Hypothetical cohorts were created by varying the sample size (n: 15-500) and assuming three scenarios (1-cost-effective; 2-non-cost-effective; 3-dominant). The COMER result was compared to the theoretical result according to the incremental cost-effectiveness ratio (ICER) and the INB, assuming a margin of error of 2,000 and 500 monetary units, respectively. The Frank copula with positive dependence (-0.4279) showed a goodness-of-fit sufficient to represent costs and QoL (p-values 0.524 and 0.808). The theoretical INB was within the 95% confidence interval of the TINB, based on 15 individuals with a probability > 80% for scenarios 1 and 2, and > 90% for scenario 3. The TINB > 0 test with 15 individuals showed p-values of 0.0105 (SD: 0.0411) for scenario 1, 0.613 (SD: 0.265) for scenario 2 and COMER is a valid tool for combining cost-effectiveness studies and may be of use to health decision makers.

  19. Oxygen Isotopic Compositions of Olivine and Pyroxene from CI Chondrites (United States)

    Leshin, L. A.; Rubin, A. E.; McKeegan, K. D.


    The oxygen isotopic compositions of carbonaceous chondrites are complicated since individual components of these meteorites have distinct isotopic compositions that have been affected, to varying degrees, by both nebular and parent body processes. We present the first measurements of oxygen isotopic compositions of rare olivine and pyroxene in the CI chondrites. By combining these data with oxygen isotopic analyses of secondary minerals in these rocks previously reported by Clayton and co-workers, we hope to place quantitative constraints on the physical processes that occurred during formation of these meteorites. The oxygen isotopic composition of separated olivine and pyroxene grains from Orgueil and Ivuna were measured using SIMS. The delta ^(18)O values of the olivines range from ~+3 to +13 and the delta^(17)O values range from ~+1 to +7. The delta^(18)O values of the pyroxenes range from ~+4 to +10 and the delta^(17)O values range from ~+2 to +5. Observations that will be explained in the interpretation of the data are: (1) CI pyroxene and olivine grains have essentially identical oxygen isotopic compositions which are distinct from those measured in other carbonaceous chondrites. (2) All data points except two are indistinguishable from terrestrial values at the one sigma level, and the two exceptions fall only slightly below the terrestrial fractionation line. We consider the data taken as a whole to be consistent with terrestrial values, as well as the slightly positive delta^(17)O values reported previously for matrix and magnetite in CI chondrites. (3) Due to the small range in d values observed relative to the uncertainties, it is not possible to distinguish whether these data fall on a line of approximately slope 1 or slope 1/2.

  20. Periodo de interferencia de arvenses en el cultivo de berenjena (Solanum melongena L.

    Directory of Open Access Journals (Sweden)

    Aramendiz-Tatis Hermes


    Full Text Available

    Dada la importancia de la berenjena en la horticultura del Caribe colombiano, el presente trabajo buscó establecer las bases de un manejo sustentable e integrado de malezas en este cultivo, basado en el período de máxima interferencia de aquellas sobre este. El estudio se realizó en la Universidad de Córdoba, ubicada en Montería (8°39’ N; 75°58’ W. El diseño experimental consistió en bloques completamente aleatorizados, con cuatro repeticiones y siete tratamientos relacionados con periodos crecientes de control de arvenses, seguidos por ausencia de control. Los resultados muestran que las arvenses con mayor presencia fueron paja mona (Leptochloa filiformis [Lam.] Beauv., caminadora (Rottboellia cochinchinensis [Lour.] W.D. Clayton, liendre de puerco (Echinochloa colona [L.] Link., coquito (Cyperus rotundus L. y bledo (Amaranthus retroflexus L.. Las arvenses afectaron la altura de la planta, el diámetro del tallo, y el rendimiento y calidad del fruto. Este último parámetro no se ve afectado cuando el cultivar lila se mantiene limpio durante los primeros 40 días. Al considerar el tipo de productor de esta hortaliza en el valle del Sinú, se sugiere utilizar: i para áreas pequeñas, métodos físicos, como el arranque manual o corte con machete u otra herramienta, y prácticas culturales; ii para áreas grandes, la combinación de herbicidas de presiembra con métodos físicos y culturales.

  1. A general maximum likelihood analysis of variance components in generalized linear models. (United States)

    Aitkin, M


    This paper describes an EM algorithm for nonparametric maximum likelihood (ML) estimation in generalized linear models with variance component structure. The algorithm provides an alternative analysis to approximate MQL and PQL analyses (McGilchrist and Aisbett, 1991, Biometrical Journal 33, 131-141; Breslow and Clayton, 1993; Journal of the American Statistical Association 88, 9-25; McGilchrist, 1994, Journal of the Royal Statistical Society, Series B 56, 61-69; Goldstein, 1995, Multilevel Statistical Models) and to GEE analyses (Liang and Zeger, 1986, Biometrika 73, 13-22). The algorithm, first given by Hinde and Wood (1987, in Longitudinal Data Analysis, 110-126), is a generalization of that for random effect models for overdispersion in generalized linear models, described in Aitkin (1996, Statistics and Computing 6, 251-262). The algorithm is initially derived as a form of Gaussian quadrature assuming a normal mixing distribution, but with only slight variation it can be used for a completely unknown mixing distribution, giving a straightforward method for the fully nonparametric ML estimation of this distribution. This is of value because the ML estimates of the GLM parameters can be sensitive to the specification of a parametric form for the mixing distribution. The nonparametric analysis can be extended straightforwardly to general random parameter models, with full NPML estimation of the joint distribution of the random parameters. This can produce substantial computational saving compared with full numerical integration over a specified parametric distribution for the random parameters. A simple method is described for obtaining correct standard errors for parameter estimates when using the EM algorithm. Several examples are discussed involving simple variance component and longitudinal models, and small-area estimation.

  2. AKT-independent PI3-K signaling in cancer – emerging role for SGK3

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    Bruhn MA


    Full Text Available Maressa A Bruhn,1,6 Richard B Pearson,1–4 Ross D Hannan,1–5 Karen E Sheppard1–3 1Division of Cancer Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; 2Sir Peter MacCallum Department of Oncology, 3Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria, Australia; 4Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia; 5School of Biomedical Sciences, University of Queensland, Brisbane, Queensland, Australia; 6School of Biological Sciences, Flinders University, Bedford Park, South Australia, Australia Abstract: The phosphoinositide 3-kinase (PI3-K signaling pathway plays an important role in a wide variety of fundamental cellular processes, largely mediated via protein kinase B/v-akt murine thymoma viral oncogene homolog (PKB/AKT signaling. Given the crucial role of PI3-K/AKT signaling in regulating processes such as cell growth, proliferation, and survival, it is not surprising that components of this pathway are frequently dysregulated in cancer, making the AKT kinase family members important therapeutic targets. The large number of clinical trials currently evaluating PI3-K pathway inhibitors as a therapeutic strategy further emphasizes this. The serum- and glucocorticoid-inducible protein kinase (SGK family is made up of three isoforms, SGK1, 2, and 3, that are PI3-K-dependent, serine/threonine kinases, with similar substrate specificity to AKT. Consequently, the SGK family also regulates similar cell processes to the AKT kinases, including cell proliferation and survival. Importantly, there is emerging evidence demonstrating that SGK3 plays a critical role in AKT-independent oncogenic signaling. This review will focus on the role of SGK3 as a key effector of AKT-independent PI3-K oncogenic signaling. Keywords: SGK3, AKT, PI3-kinase, mTOR, cancer

  3. Mineralization and leaching process in the Jian copper deposit, northeastern Fars province: Application of petrography and stable isotopes

    Directory of Open Access Journals (Sweden)

    Farid Moore


    and analysis of quartz for oxygen isotopes was performed using the standard techniques detailed by Clayton and Mayeda (Clayton and Mayeda, 1963. Fluid inclusions were extracted for δD measurement from quartz samples selected as far as possible to avoid late inclusions. The methods were standard and similar to those published in Fallick et al. (Fallick et al., 1987. Stable isotope analysis for oxygen and hydrogen isotopes was undertaken at the isotope geochemistry laboratory, University of Queensland. Results δ65Cu values for analyzed samples range from -0.45 to +0.49 ‰ in the secondary copper minerals (malachite. The δ18O values for analyzed quartz samples, collected from different quartz veins of the Jian deposit, fall in a narrow range varying from +15.8 to +18.4‰ (avg. +16.7‰ for type A veins and +16.6 to +17.9‰ (avg. +17.2‰ for type B veins. The δ18O values of the fluids calculated from the Jian quartz samples range from +7.6 to +10.7‰ (avg. +9.1 ‰ for type A veins and +4.7 to +5.1‰ (avg. +4.9 ‰ for type B veins. The δD values of the fluid inclusions hosted by quartz samples range from -33.1 to -41.2‰ (avg. -37.6‰ for type A and -52.3 to -54.9‰ (avg. -53.1‰ for type B veins. Discussion Based on mineralization style and structures, Th, salinity and composition of fluid inclusions, stable isotope systematics, timing of the mineralization with respect to deformation and metamorphism, host rocks, ore and gangue minerals, the Jian deposit can be classified either as a metamorphogenic or mesothermal Cu-bearing quartz deposit. Precipitation of secondary Cu+-sulfide minerals from the Cu+ complexes present in this fluid would result in sulfide minerals with low copper isotopic variations (-0.45 to +0.49‰ in the Jian copper deposit. This could explain why a low variation in the isotopic composition of Cu is observed in a horizontal plane. Isotopically, mineralization is most probably the result of varied isotopic fractionation processes

  4. Stream water quality in coal mined areas of the lower Cheat River Basin, West Virginia and Pennsylvania, during low-flow conditions, July 1997 (United States)

    Williams, Donald R.; Clark, Mary E.; Brown, Juliane B.


    IntroductionThe Cheat River Basin is in the Allegheny Plateau and Allegheny Mountain Sections of the Appalachian Plateau Physiographic Province (Fenneman, 1946) and is almost entirely within the state of West Virginia. The Cheat River drains an area of 1,422 square miles in Randolph, Tucker, Preston, and Monongalia Counties in West Virginia and Fayette County in Pennsylvania. From its headwaters in Randolph County, W.Va., the Cheat River flows 157 miles north to the Pennsylvania state line, where it enters the Monongahela River. The Cheat River drainage comprises approximately 19 percent of the total Monongahela River Basin. The Cheat River and streams within the Cheat River Basin are characterized by steep gradients, rock channels, and high flow velocities that have created a thriving white-water rafting industry for the area. The headwaters of the Cheat River contain some of the most pristine and aesthetic streams in West Virginia. The attraction to the area, particularly the lower part of the Cheat River Basin (the lower 412 square miles of the basin), has been suppressed because of poor water quality. The economy of the Lower Cheat River Basin has been dominated by coal mining over many decades. As a result, many abandoned deep and surface mines discharge untreated acid mine drainage (AMD), which degrades water quality, into the Cheat River and many of its tributary streams. Approximately 60 regulated mine-related discharges (West Virginia Department of Environmental Protection, 1996) and 185 abandoned mine sites (U.S. Office of Surface Mining, 1998) discharge treated and untreated AMD into the Cheat River and its tributaries.The West Virginia Department of Environmental Protection (WVDEP) Office of Abandoned Mine Lands and Reclamation (AML&R) has recently completed several AMD reclamation projects throughout the Cheat River Basin that have collectively improved the mainstem water quality. The AML&R office is currently involved in acquiring grant funds and

  5. Full-Scale Testing of a Mercury Oxidation Catalyst Upstream of a Wet FGD System

    Energy Technology Data Exchange (ETDEWEB)

    Gary Blythe; Jennifer Paradis


    This document presents and discusses results from Cooperative Agreement DE-FC26-06NT42778, 'Full-scale Testing of a Mercury Oxidation Catalyst Upstream of a Wet FGD System,' which was conducted over the time-period July 24, 2006 through June 30, 2010. The objective of the project was to demonstrate at full scale the use of solid honeycomb catalysts to promote the oxidation of elemental mercury in pulverized-coal-fired flue gas. Oxidized mercury is removed downstream in wet flue gas desulfurization (FGD) absorbers and collected with the byproducts from the FGD system. The project was co-funded by EPRI, the Lower Colorado River Authority (LCRA), who also provided the host site, Great River Energy, Johnson Matthey, Southern Company, Salt River Project (SRP), the Tennessee Valley Authority (TVA), NRG Energy, Ontario Power and Westar. URS Group was the prime contractor and also provided cofunding. The scope of this project included installing and testing a gold-based catalyst upstream of one full-scale wet FGD absorber module (about 200-MW scale) at LCRA's Fayette Power Project (FPP) Unit 3, which fires Powder River Basin coal. Installation of the catalyst involved modifying the ductwork upstream of one of three wet FGD absorbers on Unit 3, Absorber C. The FGD system uses limestone reagent, operates with forced sulfite oxidation, and normally runs with two FGD modules in service and one spare. The full-scale catalyst test was planned for 24 months to provide catalyst life data. Over the test period, data were collected on catalyst pressure drop, elemental mercury oxidation across the catalyst module, and mercury capture by the downstream wet FGD absorber. The demonstration period began on May 6, 2008 with plans for the catalyst to remain in service until May 5, 2010. However, because of continual increases in pressure drop across the catalyst and concerns that further increases would adversely affect Unit 3 operations, LCRA decided to end the

  6. Origin and formation qualification of Khur o Biabanak agates, Isfahan province

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    Forough Malek Mahmoudi


    -deuterium stable isotopic analysis. The isotopic distribution of mineral-fluid is affected by temperature changes. A variety of methods for determining the oxygen isotope distribution coefficient between quartz and fluid at different temperatures are presented. The Clayton et al. (Clayton et al., 1972 equation was used to calculate the oxygen distribution coefficient between water and quartz. 103lnα (Qz−H2O = (3.38* 1010 /T2* – 2.9 Due to the lack of water in quartz structure, all deuterium could be estimated as hydrothermal fluids deuterium. Therefore, no correction is needed. Study of oxygen and deuterium stable isotopes in two samples of silica and comparing the results with normal reservoirs of silica samples, determines the type of atmospheric water. Analysis of two silicic samples and comparison with some natural reservoirs suggests that hydrothermal fluids has atmospheric source. Discussion The Khur agates formed in the cavities of Eocene volcanics with andesitic basalt composition within the Khur bentonite horizon. Field observation indicates that the Khur agates formed independent of faults and joints. According to the XRD analysis, their composition mainly consists of silica and calcite, as well as dolomite and barite in lower quantities. Trace elements and REEs in both silicic samples and andesitic host rock has same trend with large amount of depletion in the silicic samples. Mineralogical evidence suggests that Tashtab agates formed as a result of periodic eruption of low temperature hydrothermal fluids. Also, oxygen and deuterium stable isotope data resemble hydrothermal fluids with atmospheric origin. Acknowledgments This paper stems from M.Sc. thesis carried out by the first author. It has financially been supported by the University of Isfahan. References Burkhard, M., 1993. Calcite twins, their geometry, appearance and review. Journal of Structural Geology, 15(3-5: 351-368. Clayton, R.N., O’Neil, J.R. and Mayeda, T.K, 1972. Oxygen isotope exchange between

  7. Influência do teor de polipropileno modificado com anidrido maleico nas propriedades do nanocompósito PP/EPDM/argila organofílica Influence from the concentration of interfacial agent on the properties of PP/EPDM/organoclay nanocomposites

    Directory of Open Access Journals (Sweden)

    Fernanda C. F. Braga


    Full Text Available Neste trabalho foram obtidos nanocompósitos de elastômeros termoplásticos à base de PP/EPDM/argila organofílica pela técnica de intercalação no estado fundido em câmara interna de mistura. Foram preparados concentrados de PP-MA (agente interfacial e Claytone 40 (argila organofílica nas proporções de 1:1, 2:1 e 3:1 que posteriormente foram adicionados na matriz PP/EPDM, previamente preparada, mantendo o teor de argila fixo em 5% (em massa. Foram investigadas as propriedades mecânicas de módulo elástico, tração e alongamento na ruptura, reologia e morfologia, a fim de estabelecer a influência da razão PP-MA/argila organofílica no comportamento dos nanocompósitos. Os resultados mostraram que a adição de teores crescentes de PP-MA melhorou a dispersão da argila organofílica na matriz de PP/EPDM. Conforme revelado pela difração de raio X e confirmados pela reometria foram obtidos nanocompósitos com estruturas mistas intercaladas e esfoliadas, que resultaram em maiores valores de módulo e deformação na ruptura.In this work, nanocomposites were prepared with PP/EPDM thermoplastic elastomer and organoclay by melt intercalation in an internal mixture chamber. Masterbatches composed of PP-MA/organoclay in proportions of 1:1, 2:1 and 3:1 were prepared and further added to a PP/EPDM thermoplastic elastomer, keeping the clay content fixed at 5% (by weight. The tensile properties, rheology and the morphology (organoclay dispersion, crystalline structure and crystallinity degree of nanocomposites were studied to establish the influence of the PP-MA/Organoclay ratio in the system. The results showed that the addition of increasing levels of PP-MA improved the dispersion of organoclay in the PP/EPDM matrix. As revealed in x-ray diffraction and confirmed by rheology measurements nanocomposites were obtained with mixed intercalated and exfoliated structures, resulting in higher tensile modulus and elongation at break.

  8. Assessment of Sexual Desire for Clinical Trials of Women With Hypoactive Sexual Desire Disorder: Measures, Desire-Related Behavior, and Assessment of Clinical Significance. (United States)

    Pyke, Robert E; Clayton, Anita H


    Female Sexual Function Index-desire subscale measures the most relevant element of sexual desire, but it would be meaningful to include 4 or 5 more sexual symptoms as end points: sexual thoughts/fantasies, frequency of sexual activity, receptivity, initiations, and possibly avoidance of sexual situations. The Elements of Desire Questionnaire and a measure of sexual frequency may suffice. Responder and remitter analyses show the clinical relevance of a treatment and enable comparisons across trials. Pyke RE, Clayton AH. Assessment of Sexual Desire for Clinical Trials of Women With Hypoactive Sexual Desire Disorder: Measures, Desire-Related Behavior, and Assessment of Clinical Significance. Sex Med Rev 2017;XX:XXX-XXX. Copyright © 2017 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.

  9. Development of Hybrid pH sensor for long-term seawater pH monitoring. (United States)

    Nakano, Y.; Egashira, T.; Miwa, T.; Kimoto, H.


    We have been developing the in situ pH sensor (Hybrid pH sensor: HpHS) for the long-term seawater pH monitoring. We are planning to provide the HpHS for researchers and environmental consultants for observation of the CCS (Carbon dioxide Capture and Storage) monitoring system, the coastal environment monitoring system (e.g. Blue Carbon) and ocean acidification. The HpHS has two types of pH sensors (i.e. potentiometric pH sensor and spectrophotometric pH sensor). The spectrophotometric pH sensor can measure pH correctly and stably, however it needs large power consumption and a lot of reagents in a long period of observation. The pH sensor used m-cresol purple (mCP) as an indicator of pH (Clayton and Byrne, 1993 and Liu et al., 2011). We can choose both coefficients before deployment. On the other hand, although the potentiometric pH sensor is low power consumption and high-speed response (within 10 seconds), drifts in the pH of the potentiometric measurements may possibly occur for a long-term observation. The HpHS can measure in situ pH correctly and stably combining advantage of both pH sensors. The HpHS consists of an aluminum pressure housing with optical cell (main unit) and an aluminum silicon-oil filled, pressure-compensated vessel containing pumps and valves (diaphragm pump and valve unit) and pressure-compensated reagents bags (pH indicator, pure water and Tris buffer or certified reference material: CRM) with an ability to resist water pressure to 3000m depth. The main unit holds system control boards, pump drivers, data storage (micro SD card), LED right source, photodiode, optical cell and pressure proof windows. The HpHS also has an aluminum pressure housing that holds a rechargeable lithium-ion battery or a lithium battery for the power supply (DC 24 V). The HpHS is correcting the value of the potentiometric pH sensor (measuring frequently) by the value of the spectrophotometric pH sensor (measuring less frequently). It is possible to calibrate in

  10. Tailored antihypertensive drug therapy prescribed to older women attenuates circulating levels of interleukin-6 and tumor necrosis factor-α

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    Toledo JO


    Full Text Available Juliana O Toledo,1 Clayton F Moraes,2,3 Vinícius C Souza,2 Audrey C Tonet-Furioso,2 Luís CC Afonso,4 Cláudio Córdova,3 Otávio T Nóbrega1,2 1Graduate Program in Health Sciences, 2Graduate Program in Medical Sciences, University of Brasília, Brasília, 3Graduate Program in Gerontology, Catholic University of Brasília, Brasília, 4Research Center in Biological Sciences, Federal University of Ouro Preto, Ouro Preto, Brazil Objective: To test the hypothesis that antihypertensive drug therapy produces anti-inflammatory effects in clinical practice, this study investigated circulating levels of selected proinflammatory mediators (interleukin-6 [IL-6], tumor necrosis factor-alpha [TNF-α], and interferon-γ [INF-γ] in response to multivariate drug directions for blood pressure (BP control.Methods: Prospective study involving 110 hypertensive, community-dwelling older women with different metabolic disorders. A short-term BP-lowering drug therapy was conducted according to current Brazilian guidelines on hypertension, and basal cytokine levels were measured before and after intervention.Results: Interventions were found to represent current hypertension-management practices in Brazil and corresponded to a significant reduction in systolic and diastolic BP levels in a whole-group analysis, as well as when users and nonusers of the most common therapeutic classes were considered separately. Considering all patients, mean IL-6 and TNF-α levels showed a significant decrease in circulating concentrations (P<0.01 at the endpoint compared with baseline, whereas the mean INF-γ level was not significantly different from baseline values. In separate analyses, only users of antagonists of the renin–angiotensin system and users of diuretics exhibited the same significant treatment-induced reduction in serum IL-6 and TNF-α observed in the whole group.Conclusion: Our data demonstrates that a clinically guided antihypertensive treatment is effective in

  11. A copula-based chance-constrained waste management planning method: An application to the city of Regina, Saskatchewan, Canada. (United States)

    Chen, F; Huang, G H; Fan, Y R; Wang, S


    This study proposes a copula-based chance-constrained waste management planning (CCWMP) method. The method can effectively reflect the interactions between random parameters of the waste management planning systems, and thus can help analyze the influences of their interactions on the entire systems. In particular, a joint distribution function is established using preestimated marginal distributions of random variables and an optimal copula selected from widely used Gaussian, Student's t, Clayton, Frank, Gumbel, and Ali-Mikhail-Haq copulas. Then a set of joint probabilistic constraints in the chance-constrained programming problems is converted into individual probabilistic constraints using the joint distribution function. Further, this method is applied to residential solid waste management in the city of Regina in Canada for demonstrating its applicability. Nine scenarios based on different joint and marginal probability levels are considered within a multiperiod and multizone context to effectively reflect dynamic, uncertain, and interactive characteristics of the solid waste management systems in the city. The results provide many decision alternatives under these scenarios, including cost-effective and environmentally friendly decision schemes. Moreover, the results indicate that even though the effect of the joint probability levels on the system costs is more significant than that of the marginal probability levels, the effect of marginal probability levels is notable, and there exists a trade-off between the total system cost and the constraint-violation risk. Therefore, the results obtained from the present study would be useful to support the city's long-term solid waste management planning and formulate local policies and regulation concerning the city's waste generation and management. The CCWMP method not only can solve chance-constrained problems with unknown probability distributions of random variables in the right-hand sides of constraints, but

  12. Dynamic Topography Revisited (United States)

    Moresi, Louis


    Dynamic Topography Revisited Dynamic topography is usually considered to be one of the trinity of contributing causes to the Earth's non-hydrostatic topography along with the long-term elastic strength of the lithosphere and isostatic responses to density anomalies within the lithosphere. Dynamic topography, thought of this way, is what is left over when other sources of support have been eliminated. An alternate and explicit definition of dynamic topography is that deflection of the surface which is attributable to creeping viscous flow. The problem with the first definition of dynamic topography is 1) that the lithosphere is almost certainly a visco-elastic / brittle layer with no absolute boundary between flowing and static regions, and 2) the lithosphere is, a thermal / compositional boundary layer in which some buoyancy is attributable to immutable, intrinsic density variations and some is due to thermal anomalies which are coupled to the flow. In each case, it is difficult to draw a sharp line between each contribution to the overall topography. The second definition of dynamic topography does seem cleaner / more precise but it suffers from the problem that it is not measurable in practice. On the other hand, this approach has resulted in a rich literature concerning the analysis of large scale geoid and topography and the relation to buoyancy and mechanical properties of the Earth [e.g. refs 1,2,3] In convection models with viscous, elastic, brittle rheology and compositional buoyancy, however, it is possible to examine how the surface topography (and geoid) are supported and how different ways of interpreting the "observable" fields introduce different biases. This is what we will do. References (a.k.a. homework) [1] Hager, B. H., R. W. Clayton, M. A. Richards, R. P. Comer, and A. M. Dziewonski (1985), Lower mantle heterogeneity, dynamic topography and the geoid, Nature, 313(6003), 541-545, doi:10.1038/313541a0. [2] Parsons, B., and S. Daly (1983), The

  13. Priorities in the primary care of persons experiencing homelessness: convergence and divergence in the views of patients and provider/experts

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    Steward J


    Full Text Available Jocelyn Steward,1 Cheryl L Holt,2 David E Pollio,3 Erika L Austin,4,5 Nancy Johnson,4 Adam J Gordon,6,7 Stefan G Kertesz4,81Department of Health Care Management, Clayton State University, Morrow, GA, 2Department of Psychology, University of Maryland, College Park, MD, 3Department of Social Work, University of Alabama at Birmingham, 4Birmingham VA Medical Center, 5Department of Biostatistics, University of Alabama at Birmingham School of Public Health, Birmingham, AL, 6VA Pittsburgh Health Care System, 7University of Pittsburgh School of Medicine, Pittsburgh, PA, 8Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USAPurpose: Homeless individuals face unique challenges in health care. Several US initiatives seeking to advance patient-centered primary care for homeless persons are more likely to succeed if they incorporate the priorities of the patients they are to serve. However, there has been no prior research to elicit their priorities in primary care. This study sought to identify aspects of primary care important to persons familiar with homelessness based on personal experience or professional commitment, and to highlight where the priorities of patients and professionals dedicated to their care converge or diverge.Methods: This qualitative exercise asked 26 homeless patients and ten provider/experts to rank 16 aspects of primary care using a card sort. Patient-level respondents (n=26 were recruited from homeless service organizations across all regions of the USA and from an established board of homeless service users. Provider/expert-level respondents (n=10 were recruited from veteran and non-veteran-focused homeless health care programs with similar geographic diversity.Results: Both groups gave high priority to accessibility, evidence-based care, coordination, and cooperation. Provider/experts endorsed patient control more strongly than patients. Patients ranked information about their care

  14. Modeling and analysis of personal exposures to VOC mixtures using copulas (United States)

    Su, Feng-Chiao; Mukherjee, Bhramar; Batterman, Stuart


    Environmental exposures typically involve mixtures of pollutants, which must be understood to evaluate cumulative risks, that is, the likelihood of adverse health effects arising from two or more chemicals. This study uses several powerful techniques to characterize dependency structures of mixture components in personal exposure measurements of volatile organic compounds (VOCs) with aims of advancing the understanding of environmental mixtures, improving the ability to model mixture components in a statistically valid manner, and demonstrating broadly applicable techniques. We first describe characteristics of mixtures and introduce several terms, including the mixture fraction which represents a mixture component's share of the total concentration of the mixture. Next, using VOC exposure data collected in the Relationship of Indoor Outdoor and Personal Air (RIOPA) study, mixtures are identified using positive matrix factorization (PMF) and by toxicological mode of action. Dependency structures of mixture components are examined using mixture fractions and modeled using copulas, which address dependencies of multiple variables across the entire distribution. Five candidate copulas (Gaussian, t, Gumbel, Clayton, and Frank) are evaluated, and the performance of fitted models was evaluated using simulation and mixture fractions. Cumulative cancer risks are calculated for mixtures, and results from copulas and multivariate lognormal models are compared to risks calculated using the observed data. Results obtained using the RIOPA dataset showed four VOC mixtures, representing gasoline vapor, vehicle exhaust, chlorinated solvents and disinfection by-products, and cleaning products and odorants. Often, a single compound dominated the mixture, however, mixture fractions were generally heterogeneous in that the VOC composition of the mixture changed with concentration. Three mixtures were identified by mode of action, representing VOCs associated with hematopoietic, liver

  15. Estabelecimento do capim setária cv. Kazungula em condições de inundação

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    Haddad Cláudio Maluf


    Full Text Available Este experimento teve como objetivo conhecer o comportamento da Setaria sphacelata (Schumach. Moss var. sericea (Stapf Clayton cv. Kazungula quanto a capacidade de sobrevivência em diferentes condições de inundação por ocasião de seu estabelecimento. O mesmo foi dividido em duas etapas e instalado em condições de campo, utilizando-se caixas de cimento amianto cheias com solo de várzea. O delineamento estatístico adotado foi inteiramente casualizado com quatro repetições. Para a primeira etapa foram impostos como tratamentos as épocas de inundação: 0, 10, 20, 30 e 40 dias após a semeadura com duração de 10 dias, sendo a testemunha irrigada por aspersão normal. Com exceção do tratamento onde a inundação foi iniciada 10 dias após a semeadura, não existiu diferença (P<0,01 entre o número de plantas emergidas ao final dessa etapa experimental. Foi observada uma tendência de superioridade no tratamento cuja época de inundação foi imediata à semeadura, sugerindo um possível estímulo da inundação na germinação das sementes dessa espécie. Na segunda etapa os tratamentos foram: inundação por 15, 20, 25, 30 e 35 dias de duração imediatamente após a semeadura, sendo a testemunha irrigação por aspersão normal. Os resultados indicam que inundações por 15 dias ou mais, nas condições do experimento, comprometem o potencial de germinação das sementes, diminuindo o número de plantas emergidas (P<0,05 e portanto prejudicando o estabelecimento.

  16. Effect Size in Efficacy Trials of Women With Decreased Sexual Desire. (United States)

    Pyke, Robert E; Clayton, Anita H


    Regarding hypoactive sexual desire disorder (HSDD) in women, some reviewers judge the effect size small for medications vs placebo, but substantial for cognitive behavior therapy (CBT) or mindfulness meditation training (MMT) vs wait list. However, we lack comparisons of the effect sizes for the active intervention itself, for the control treatment, and for the differential between the two. For efficacy trials of HSDD in women, compare effect sizes for medications (testosterone/testosterone transdermal system, flibanserin, and bremelanotide) and placebo vs effect sizes for psychotherapy and wait-list control. We conducted a literature search for mean changes and SD on main measures of sexual desire and associated distress in trials of medications, CBT, or MMT. Effect size was used as it measures the magnitude of the intervention without confounding by sample size. Cohen d was used to determine effect sizes. For medications, mean (SD) effect size was 1.0 (0.34); for CBT and MMT, 1.0 (0.36); for placebo, 0.55 (0.16); and for wait list, 0.05 (0.26). Recommendations of psychotherapy over medication for treatment of HSDD are premature and not supported by data on effect sizes. Active participation in treatment conveys considerable non-specific benefits. Caregivers should attend to biological and psychosocial elements, and patient preference, to optimize response. Few clinical trials of psychotherapies were substantial in size or utilized adequate control paradigms. Medications and psychotherapies had similar, large effect sizes. Effect size of placebo was moderate. Effect size of wait-list control was very small, about one quarter that of placebo. Thus, a substantial non-specific therapeutic effect is associated with receiving placebo plus active care and evaluation. The difference in effect size between placebo and wait-list controls distorts the value of the subtraction of effect of the control paradigms to estimate intervention effectiveness. Pyke RE, Clayton AH

  17. Incidence of non-physiologically complex surgical procedures performed in children: an Ontario population-based study of health administrative data. (United States)

    O'Leary, James D; Dexter, Franklin; Faraoni, David; Crawford, Mark W


    Quantification of surgical procedures undertaken by hospitals is necessary for informing resource allocation and modelling healthcare services. Our objective was to quantify the incidence, similarity, and diversity of non-physiologically complex surgical procedures performed at pediatric specialist hospitals and other hospitals performing pediatric surgery. We conducted a population-based cohort study of children aged 28 days to 18 yr who underwent surgery in the province of Ontario from 2007 to 2015 using healthcare administrative databases. We estimated the incidence of non-physiologically complex procedures (i.e., ≤ 7 basic units in the 2015 Ontario Health Insurance Plan Schedule of Benefits) performed in pediatric specialist hospitals and other hospitals performing pediatric surgery. We used Yue and Clayton's index and the effective number of common procedures (1/Herfindahl index) to quantify the similarity and diversity of pediatric surgical procedures performed in these hospital types. Overall, 830,830 pediatric surgical procedures were performed in 158 Ontario hospitals during the eight-year study period. Most surgical procedures performed at hospitals performing pediatric surgery were non-physiologically complex (vs 50%, P < 0.001). The incidence of non-physiologically complex procedures increased progressively each year at pediatric specialist hospitals and was associated with a reciprocal decline among the other hospitals. Comparing pediatric specialist hospitals with the other hospitals, the mean similarity index for non-physiologically complex procedures was less than moderate (0.52; 95% confidence interval [CI], 0.51 to 0.54). The mean effective number of common non-physiologically complex procedures (i.e., the diversity) among the pediatric specialist hospitals was greater than at the other 154 hospitals performing pediatric surgery (65.3 vs 21.8 procedures, respectively; mean difference, 43.5; 95% CI, 42.2 to 44.8; P < 0.001). Non

  18. Microbial communities in the reef water at Kham Island, lower Gulf of Thailand

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    Naraporn Somboonna


    Full Text Available Coral reefs are among the most biodiverse habitats on Earth, but knowledge of their associated marinemicrobiome remains limited. To increase the understanding of the coral reef ecosystem in the lower Gulf of Thailand, this study utilized 16S and 18S rRNA gene-based pyrosequencing to identify the prokaryotic and eukaryotic microbiota present in the reef water at Kham Island, Trat province, Thailand (N6.97 E100.86. The obtained result was then compared with the published microbiota from different coral reef water and marine sites. The coral reefs at Kham Island are of the fringe type. The reefs remain preserved and abundant. The community similarity indices (i.e., Lennon similarity index, Yue & Clayton similarity index indicated that the prokaryotic composition of Kham was closely related to that of Kra, another fringing reef site in the lower Gulf of Thailand, followed by coral reef water microbiota at GS048b (Cooks Bay, Fr. Polynesia, Palmyra (Northern Line Islands, United States and GS108b (Coccos Keeling, Australia, respectively. Additionally, the microbial eukaryotic populations at Kham was analyzed and compared with the available database at Kra. Both eukaryotic microbiota, in summer and winter seasons, were correlated. An abundance of Dinophysis acuminata was noted in the summer season, in accordance with its reported cause of diarrhoeatic shellfish outbreak in the summer season elsewhere. The slightly lower biodiversity in Kham than at Kra might reflect the partly habitat difference due to coastal anthropogenic activities and minor water circulation, as Kham locates close to the mainland and is surrounded by islands (e.g., Chang and Kut islands. The global marine microbiota comparison suggested relatively similar microbial structures among coral sites irrespective of geographical location, supporting the importance of coral-associated marine microbiomes, and Spearman’s correlation analysis between community membership and factors of

  19. Groundwater conditions in Georgia, 2015–16 (United States)

    Gordon, Debbie W.; Painter, Jaime A.


    The U.S. Geological Survey collects groundwater data and conducts studies to monitor hydrologic conditions, define groundwater resources, and address problems related to water supply, water use, and water quality. In Georgia, water levels were monitored continuously at 157 wells during calendar years 2015 and 2016. Because of missing data or short periods of record (less than 5 years) for several of these wells, data for 147 wells are presented in this report. These wells include 15 in the surficial aquifer system, 18 in the Brunswick aquifer system and equivalent sediments, 59 in the Upper Floridan aquifer, 13 in the Lower Floridan aquifer and underlying units, 9 in the Claiborne aquifer, 1 in the Gordon aquifer, 8 in the Clayton aquifer, 16 in the Cretaceous aquifer system, 2 in Paleozoic-rock aquifers, and 6 in crystalline-rock aquifers. Data from the well network indicate that water levels generally rose during the 10-year period from 2007 through 2016, with water levels rising in 105 wells and declining in 31 wells; insufficient data prevented determination of a 10-year trend in 11 wells. Water levels declined over the long-term period of record at 80 wells, increased at 62 wells, and remained relatively constant at 5 wells.In addition to continuous water-level data, periodic water-level data were collected and used to construct potentiometric-surface maps for the Upper Floridan aquifer in the Brunswick–Glynn County area during October 2015 and October 2016 and in the Albany–Dougherty County area during December 2015 and November and December 2016. Periodic water-level measurements were also collected and used to construct potentiometric-surface maps for the Cretaceous aquifer system in the Augusta–Richmond County area during July 2015 and June 2016. In general, water levels in the Upper Floridan aquifer were higher during 2015 than during 2016 in the Brunswick–Glynn County and Albany–Dougherty County areas due to higher precipitation during 2015

  20. Community perceptions of a rural medical school: a pilot qualitative study

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    Nestel D


    Full Text Available Debra Nestel,1 Katherine Gray,1 Margaret Simmons,1 Shane A Pritchard,1 Rumana Islam,1 Wan Q Eng,1 Adrian Ng,1 Tim Dornan2 1Gippsland Medical School/School of Rural Health, Monash University, Clayton, Australia; 2School of Health Professions Education, Maastricht University, Maastricht, the Netherlands Background: This paper explores local community perceptions of a relatively new rural medical school. For the purposes of this paper, community engagement is conceptualized as involvement in planning, delivering, and evaluating the medical program. Although there are several reviews of patient involvement in medical curricula development, this study was designed to pilot an approach to exploring the perspectives of well members of the community in the transition of institutional policy on community engagement to one medical school. Methods: An advertisement in the local newspaper invited volunteers to participate in a telephone interview about the new medical school. An independent researcher external to the medical school conducted the interviews using a topic guide. Audio recordings were not made, but detailed notes including verbatim statements were recorded. At least two research team members analyzed interview records for emergent themes. Human research ethics approval was obtained. Results: Twelve interviews were conducted. Participants offered rich imaginings on the role of the school and expectations and opportunities for students. Most participants expressed strong and positive views, especially in addressing long-term health workforce issues. It was considered important that students live, mix, and study in the community. Some participants had very clear ideas about the need of the school to address specified needs, such as indigenous health, obesity, aging, drug and alcohol problems, teenage pregnancy, ethnic diversity, and working with people of low socioeconomic status. Conclusion: This study has initiated a dialogue with potential

  1. Clinical role of brexpiprazole in depression and schizophrenia

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    Parikh NB


    Full Text Available Nishant B Parikh, Diana M Robinson, Anita H Clayton Psychiatry and Neurobehavioral Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA Abstract: Brexpiprazole, a serotonin–dopamine activity modulator, is the second D2 partial agonist to come to market and has been approved for the treatment of schizophrenia and as an adjunctive treatment in major depressive disorder. With less intrinsic activity than aripiprazole at the D2 receptor and higher potency at 5-HT2A, 5-HT1A, and α1B receptors, the pharmacological properties of brexpiprazole suggest a more tolerable side effect profile with regard to akathisia, extrapyramidal dysfunction, and sedation. While no head-to-head data are currently available, double-blind placebo-controlled studies show favorable results, with the number needed to treat (NNT vs placebo of 6–15 for response in acute schizophrenia treatment and 4 for maintenance. NNT is 12 for response and 17–31 for remission vs placebo in major depression. In schizophrenia trials, treatment-emergent adverse effects (TEAEs and discontinuation rates due to TEAEs were lower in treatment groups vs placebo (7.1%–9.2% vs 14.7%, respectively. Meanwhile, discontinuation rates due to TEAEs in depression studies were higher in treatment groups vs placebo (1.3%–3.5% vs 0–1.4%, respectively and appeared dose dependent. Rates of akathisia are lower compared to those with aripiprazole and cariprazine, weight gain is more prominent than with aripiprazole, cariprazine, or ziprasidone, and sedation is less than with aripiprazole but more than with cariprazine. Brexpiprazole target dosing is 2–4 mg in schizophrenia and 2 mg in depression augmentation. Dose adjustments should be considered in hepatic or renal dysfunction and/or in poor cytochrome P450 2D6 metabolizers. While brexpiprazole represents an exciting second entry for D2 partial agonists with positive studies thus far, direct head-to-head comparisons will

  2. Conservation practice establishment in two northeast Iowa watersheds: Strategies, water quality implications, and lessons learned (United States)

    Gassman, P.W.; Tisl, J.A.; Palas, E.A.; Fields, C.L.; Isenhart, T.M.; Schilling, K.E.; Wolter, C.F.; Seigley, L.S.; Helmers, M.J.


    Coldwater trout streams are important natural resources in northeast Iowa. Extensive efforts have been made by state and federal agencies to protect and improve water quality in northeast Iowa streams that include Sny Magill Creek and Bloody Run Creek, which are located in Clayton County. A series of three water quality projects were implemented in Sny Magill Creek watershed during 1988 to 1999, which were supported by multiple agencies and focused on best management practice (BMP) adoption. Water quality monitoring was performed during 1992 to 2001 to assess the impact of these installed BMPs in the Sny Magill Creek watershed using a paired watershed approach, where the Bloody Run Creek watershed served as the control. Conservation practice adoption still occurred in the Bloody Run Creek watershed during the 10-year monitoring project and accelerated after the project ended, when a multiagency supported water quality project was implemented during 2002 to 2007. Statistical analysis of the paired watershed results using a pre/post model indicated that discharge increased 8% in Sny Magill Creek watershed relative to the Bloody Run Creek watershed, turbidity declined 41%, total suspended sediment declined 7%, and NOx-N (nitrate-nitrogen plus nitrite-nitrogen) increased 15%. Similar results were obtained with a gradual change statistical model.The weak sediment reductions and increased NOx-N levels were both unexpected and indicate that dynamics between adopted BMPs and stream systems need to be better understood. Fish surveys indicate that conditions for supporting trout fisheries have improved in both streams. Important lessons to be taken from the overall study include (1) committed project coordinators, agency collaborators, and landowners/producers are all needed for successful water quality projects; (2) smaller watershed areas should be used in paired studies; (3) reductions in stream discharge may be required in these systems in order for significant sediment

  3. Police custody health care: a review of health morbidity, models of care and innovations within police custody in the UK, with international comparisons

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    McKinnon IG


    Full Text Available Iain G McKinnon,1,2 Stuart DM Thomas,3–5 Heather L Noga,6 Jane Senior7 1Institute of Health and Society, Newcastle University, Academic Psychiatry, Campus for Ageing and Vitality, 2Northumberland Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK; 3School of Global, Urban and Social Studies, RMIT University, Melbourne, VIC, 4Legal Intersections Research Centre, University of Wollongong, Wollongong, NSW, 5Southern Clinical School, Monash University, Clayton, VIC, Australia; 6School of Criminology, Simon Fraser University, Burnaby, BC, Canada; 7Offender Health Research Network, University of Manchester, Manchester, UK Abstract: This paper is a scoping review of the available evidence regarding health care issues in police custody. It describes the types and prevalence of health disorders encountered in custody and provides an overview of current practice and recent innovations in police custody health care. In contrast to the health of prisoners, the health of police custody detainees has, until recently, received little academic or clinical attention. Studies on health care in police custody identified for this review are limited to a few geographical jurisdictions, including the UK, continental Europe, North America, and Australia. There are significant health concerns among police detainees including acute injury, chronic physical health problems, mental and cognitive disorders, and the risks associated with drug and alcohol intoxication or withdrawal. There is some evidence that deaths in police custody have reduced where attention has been paid to the latter issue. Police personnel continue to experience difficulties identifying detainees with health issues relevant to their safe detention, but research shows that the use of evidence-based screening tools improves detection of such morbidities. Innovations in police custody health care mainly relate to detainees with mental disorders, including improved identification of illness

  4. Identification of the third/extra allele for forensic application in cases with TPOX tri-allelic pattern. (United States)

    Picanço, Juliane Bentes; Raimann, Paulo Eduardo; Motta, Carlos Henrique Ares Silveira da; Rodenbusch, Rodrigo; Gusmão, Leonor; Alho, Clarice Sampaio


    Genotyping of polymorphic short tandem repeats (STRs) loci is widely used in forensic DNA analysis. STR loci eventually present tri-allelic pattern as a genotyping irregularity and, in that situation, the doubt about the tri-allele locus frequency calculation can reduce the analysis strength. In the TPOX human STR locus, tri-allelic genotypes have been reported with a widely varied frequency among human populations. We investigate whether there is a single extra allele (the third allele) in the TPOX tri-allelic pattern, what it is, and where it is, aiming to understand its genomic anatomy and to propose the knowledge of this TPOX extra allele from genetic profile, thus preserving the two standard TPOX alleles in forensic analyses. We looked for TPOX tri-allelic subjects in 75,113 Brazilian families. Considering only the parental generation (mother+father) we had 150,226 unrelated subjects evaluated. From this total, we found 88 unrelated subjects with tri-allelic pattern in the TPOX locus (0.06%; 88/150,226). Seventy three of these 88 subjects (73/88; 83%) had the Clayton's original Type 2 tri-allelic pattern (three peaks of even intensity). The remaining 17% (15/88) show a new Type 2 derived category with heterozygote peak imbalance (one double dose peak plus one regular sized peak). In this paper we present detailed data from 66 trios (mother+father+child) with true biological relationships. In 39 of these families (39/66; 59%) the extra TPOX allele was transmitted either from the mother or from the father to the child. Evidences indicated the allele 10 as the extra TPOX allele, and it is on the X chromosome. The present data, which support the previous Lane hypothesis, improve the knowledge about tri-allelic pattern of TPOX CODIS' locus allowing the use of TPOX profile in forensic analyses even when with tri-allelic pattern. This evaluation is now available for different forensic applications. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  5. Validation of Progression-Free Survival as a Surrogate Endpoint for Overall Survival in Malignant Mesothelioma: Analysis of Cancer and Leukemia Group B and North Central Cancer Treatment Group (Alliance) Trials. (United States)

    Wang, Xiaofei; Wang, Xiaoyi; Hodgson, Lydia; George, Stephen L; Sargent, Daniel J; Foster, Nate R; Ganti, Apar Kishor; Stinchcombe, Thomas E; Crawford, Jeffrey; Kratzke, Robert; Adjei, Alex A; Kindler, Hedy L; Vokes, Everett E; Pang, Herbert


    The aim of this study was to investigate whether progression-free survival (PFS) can be considered a surrogate endpoint for overall survival (OS) in malignant mesothelioma. Individual data were collected from 15 Cancer and Leukemia Group B (615 patients) and 2 North Central Cancer Treatment Group (101 patients) phase II trials. The effects of 5 risk factors for OS and PFS, including age, histology, performance status (PS), white blood cell count, and European Organisation for Research and Treatment of Cancer (EORTC) risk score, were used in the analysis. Individual-level surrogacy was assessed by Kendall's tau through a Clayton bivariate Copula survival (CBCS) model. Summary-level surrogacy was evaluated via the association between logarithms of the hazard ratio (log HR)-log HR OS and log HR PFS -measured in R 2 from a weighted least-square (WLS) regression model and the CBCS model. The median PFS for all patients was 3.0 months (95% confidence interval [CI], 2.8-3.5 months) and the median OS was 7.2 months (95% CI, 6.5-8.0 months). Moderate correlations between PFS and OS were observed across all risk factors at the individual level, with Kendall's tau ranging from 0.46 to 0.47. The summary-level surrogacy varied among risk factors. The Copula R 2 ranged from 0.51 for PS to 0.78 for histology. The WLS R 2 ranged from 0.26 for EORTC and PS to 0.67 for age. The analyses demonstrated low to moderate individual-level surrogacy between PFS and OS. At the summary level, the surrogacy between PFS and OS varied significantly across different risk factors. With a short postprogression survival and a moderate correlation between PFS and OS, there is no evidence that PFS is a valid surrogate endpoint for OS in malignant mesothelioma. The Oncologist 2017;22:189-198 Implications for Practice: For better disease management and for more efficient clinical trial designs, it is important to know if progression-free survival (PFS) is a good surrogate endpoint for overall survival

  6. A novel nanobody specific for respiratory surfactant protein A has potential for lung targeting

    Directory of Open Access Journals (Sweden)

    Wang SM


    Full Text Available Shan-Mei Wang,1,* Xian He,2,* Nan Li,1,* Feng Yu,3 Yang Hu,1 Liu-Sheng Wang,1 Peng Zhang,4 Yu-Kui Du,1 Shan-Shan Du,1 Zhao-Fang Yin,1 Ya-Ru Wei,1 Xavier Mulet,5 Greg Coia,6 Dong Weng,1 Jian-Hua He,3 Min Wu,7 Hui-Ping Li1 1Department of Respiratory Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 2School of Medicine, Suzhou University, SuZhou, 3Shanghai Institute of Applied Physics, Chinese Academy of Sciences, 4Department of Chest Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of China; 5CSIRO (Commonwealth Scientific and Industrial Research Materials Science and Engineering, Clayton, 6CSIRO Materials Science and Engineering, Parkville, Melbourne, VIC, Australia; 7Department of Basic Sciences, University of North Dakota, Grand Forks, ND, USA *These authors contributed equally to this work Abstract: Lung-targeting drugs are thought to be potential therapies of refractory lung diseases by maximizing local drug concentrations in the lung to avoid systemic circulation. However, a major limitation in developing lung-targeted drugs is the acquirement of lung-specific ligands. Pulmonary surfactant protein A (SPA is predominantly synthesized by type II alveolar epithelial cells, and may serve as a potential lung-targeting ligand. Here, we generated recombinant rat pulmonary SPA (rSPA as an antigen and immunized an alpaca to produce two nanobodies (the smallest naturally occurring antibodies specific for rSPA, designated Nb6 and Nb17. To assess these nanobodies’ potential for lung targeting, we evaluated their specificity to lung tissue and toxicity in mice. Using immunohistochemistry, we demonstrated that these anti-rSPA nanobodies selectively bound to rat lungs with high affinity. Furthermore, we intravenously injected fluorescein isothiocyanate-Nb17 in nude mice and observed its preferential accumulation in the lung to other tissues, suggesting high

  7. Utility of MODIS Aerosol Optical Depth for Estimating PM2.5 Exposure in Environmental Public Health Surveillance (United States)

    Al-Hamdan, Mohammad; Crosson, William; Limaye, Ashutosh; Rickman, Doug; Quattrochi, Dale; Estes, Maury; Adeniyi, Kafayat; Qualters, Judith; Niskar, Amanda Sue


    As part of the National Environmental Public Health Tracking Network (EPHTN) the National Center for Environmental Health (NCEH) at the Centers for Disease Control and Prevention (CDC) is leading a project called Health and Environment Linked for Information Exchange (HELIX-Atlanta). The goal of developing the National Environmental Public Health Tracking Network is to improve the health of communities. Currently, few systems exist at the state or national level to concurrently track many of the exposures and health effects that might be associated with environmental hazards. An additional challenge is estimating exposure to environmental hazards such as particulate matter whose aerodynamic diameter is less than or equal to 2.5 micrometers (PM(2.5)) HELIX-Atlanta's goal is to examine the feasibility of building an integrated electronic health and environmental data network in five counties of Metropolitan Atlanta, GA (Clayton, Cobb, DeKalb, Fulton, and Gwinnett counties). Under HELIX-Atlanta, pilot projects are being conducted to develop methods to characterize exposure; link health and environmental data; analyze the relationship between health and environmental factors; and communicate findings. NASA Marshall Space Flight Center (NASA/MSFC) is collaborating with CDC to combine NASA earth science satellite observations related to air quality and environmental monitoring data to model surface estimates of PM(2.5) concentrations that can be linked with clinic visits for asthma. From 1999-2000 there were over 9,400 hospitalizations per year in Georgia with asthma as the primary diagnosis. The majority of these hospitalizations occurred in medical facilities in the five most populous Metro-Atlanta counties. Hospital charges resulting from asthma in Georgia are approximately $59 million dollars annually. There is evidence in the research literature that asthmatic persons are at increased risk of developing asthma exacerbations with exposure to environmental factors

  8. Intermittent saline flushes or continuous saline infusion: what works better when heparin-free dialysis is recommended?

    Directory of Open Access Journals (Sweden)

    Zimbudzi E


    Full Text Available Edward Zimbudzi Department of Nephrology, Monash Health, Monash Medical Centre, Clayton, Melbourne, VIC, Australia Introduction: Coagulation-free dialysis, also commonly known as “heparin-free” dialysis, can be a challenging procedure as it increases the risk of clotting the dialysis circuit. Utilizing a better saline flushing technique can lead to improved patient outcomes as well as huge financial benefits to the health institution. The purpose of this study was to compare the effectiveness of continuous saline infusion (CSI and intermittent saline flushing (ISF in preventing clotting of the dialysis extracorporeal circuit (ECC. Methods: Fifty heparin-free treatments were randomized into two treatment arms, namely CSI and ISF. Predialysis full blood count and coagulation studies were performed for all patients. During ISF, 100 mL saline was infused via the arterial line every 30 minutes while occluding the blood inlet line. Normal saline was infused into the ECC at a rate of 200 mL/hour throughout the duration of dialysis under CSI. The ECC was inspected for clotting and graded accordingly post-dialysis. Results: Seventy-six percent of the CSI treatments were completed without losing the ECC while 52% of the ISF treatments were also successful. Patients who were treated with CSI were less likely to have clotted ECCs (odds ratio 3.4, 95% CI, 1.04 to 11.2; P = 0.04. No significant differences existed between the two groups’ hematological factors that could influence clotting, such as hemoglobin and platelets. Conclusion: This study demonstrates that, when heparin-free dialysis is indicated, CSI might be a better method of preventing the ECC from clotting. There is a greater chance of realizing long-term benefits to patients and the health service with the CSI method since there is a likelihood of a reduction in the use of erythropoietin-stimulating agents and blood transfusions with the CSI method. Keywords: continuous saline infusion

  9. A Mystery Unraveled: Booming Sand Dunes (United States)

    Vriend, N. M.; Hunt, M. L.; Clayton, R. W.


    layer. Different source mechanisms are used in order to simulate the squeaking and booming emission within the dune. špace{.1in} {\\footnotesize Vriend, N. M., M. L. Hunt, R. W. Clayton, C E. Brennen, K. S. Brantley, and A. Ruiz-Angulo (2007), Solving the mystery of booming sand dunes, Geophys. Res. Lett., 34, L16306, doi:10.1029/2007GL030276.}

  10. Characterizing sexual function in patients with generalized anxiety disorder: a pooled analysis of three vilazodone studies

    Directory of Open Access Journals (Sweden)

    Clayton AH


    Full Text Available Anita H Clayton,1 Suresh Durgam,2 Xiongwen Tang,2 Changzheng Chen,2 Adam Ruth,3 Carl Gommoll2 1Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA, 2Forest Research Institute, Jersey City, NJ, 3Prescott Medical Communications Group, Chicago, IL, USA Background: Vilazodone has been shown to reduce core symptoms of generalized anxiety disorder (GAD in three randomized, double-blind, placebo-controlled trials. Since sexual dysfunction (SD is not well characterized in GAD, a post hoc analysis of these trials was conducted to evaluate the effects of vilazodone on sexual functioning in GAD patients. Materials and methods: Data were pooled from one fixed-dose trial of vilazodone 20 and 40 mg/day (NCT01629966 and two flexible-dose studies of vilazodone 20–40 mg/day (NCT01766401, NCT01844115 in adults with GAD. Sexual functioning was assessed using the Changes in Sexual Functioning Questionnaire (CSFQ. Outcomes included mean change from baseline to end of treatment (EOT in CSFQ total score and percentage of patients shifting from SD at baseline (CSFQ total score ≤47 for males, ≤41 for females to normal functioning at EOT. Treatment-emergent adverse events related to sexual functioning were also analyzed. Results: A total of 1,373 patients were included in the analyses. SD at baseline was more common in females (placebo, 46.4%; vilazodone, 49% than in males (placebo, 35.1%; vilazodone, 40.9%. CSFQ total score improvement was found in both females (placebo, +1.2; vilazodone, +1.6 and males (placebo, +2.1; vilazodone, +1.0, with no statistically significant differences between treatment groups. The percentage of patients who shifted from SD at baseline to normal sexual functioning at EOT was higher in males (placebo, 40.6%; vilazodone, 35.7% than in females (placebo, 24.9%; vilazodone, 34.9%; no statistical testing was performed. Except for erectile dysfunction and delayed ejaculation in vilazodone

  11. Prediction of lateral surface, volume and sphericity of pomegranate using MLP artificial neural network

    Directory of Open Access Journals (Sweden)

    A Rohani


    Full Text Available Introduction: Fast and accurate determination of geometrical properties of agricultural products has many applications in agricultural operations like planting, cultivating, harvesting and post-harvesting. Calculations related to storing, shipping and storage-coating materials as well as peeling time and surface-microbial concentrations are some applications of estimating product volume and surface area. Sphericity is also a parameter by which the shape differences between fruits, vegetables, grains and seeds can be quantified. This parameter is important in grading systems and inspecting rolling capability of agricultural products. Bayram presented a new dimensional method and equation to calculate the sphericity of certain shapesand some granular food materials (Bayram, 2005. Kumar and Mathew proposed atheoretically soundmethod for estimating the surface area of ellipsoidal food materials (Kumar and Mathew, 2003. Clayton et al. used non-linear regression models for calculation of apple surface area using the fruit mass or volume (Clayton et al., 1995. Humeida and Hobani predicted surface area and volume of pomegranates based on the weight and geometrical diametermean (Humeida and Hobani, 1993. Wang and Nguang designeda low cost sensor system to automatically compute the volume and surface area of axi-symmetricagricultural products such as eggs, lemons, limes and tamarillos (Wang and Nguang, 2007. The main objective of this study was to investigate the potential of Artificial Neural Network (ANN technique as an alternative method to predict the volume, surface area and sphericity of pomegranates. Materials and methods: The water displacement method (WDM was used for measuring the actual volume of pomegranates. Also, the sphericity and surface area are computed by using analytical methods. In this study, the neural MLP models were designed based upon the three nominal diameters of pomegranatesas variable inputs, while the output model consisted

  12. Total nitrogen and suspended-sediment loads and identification of suspended-sediment sources in the Laurel Hill Creek watershed, Somerset County, Pennsylvania, water years 2010-11 (United States)

    Sloto, Ronald A.; Gellis, Allen C.; Galeone, Daniel G.


    Laurel Hill Creek is a watershed of 125 square miles located mostly in Somerset County, Pennsylvania, with small areas extending into Fayette and Westmoreland Counties. The upper part of the watershed is on the Pennsylvania Department of Environmental Protection 303(d) list of impaired streams because of siltation, nutrients, and low dissolved oxygen concentrations. The objectives of this study were to (1) estimate the annual sediment load, (2) estimate the annual nitrogen load, and (3) identify the major sources of fine-grained sediment using the sediment-fingerprinting approach. This study by the U.S. Geological Survey (USGS) was done in cooperation with the Somerset County Conservation District. Discharge, suspended-sediment, and nutrient data were collected at two streamflow-gaging stations—Laurel Hill Creek near Bakersville, Pa., (station 03079600) and Laurel Hill Creek at Ursina, Pa., (station 03080000)—and one ungaged stream site, Laurel Hill Creek below Laurel Hill Creek Lake at Trent (station 03079655). Concentrations of nutrients generally were low. Concentrations of ammonia were less than 0.2 milligrams per liter (mg/L), and concentrations of phosphorus were less than 0.3 mg/L. Most concentrations of phosphorus were less than the detection limit of 0.02 mg/L. Most water samples had concentrations of nitrate plus nitrite less than 1.0 mg/L. At the Bakersville station, concentrations of total nitrogen ranged from 0.63 to 1.3 mg/L in base-flow samples and from 0.57 to 1.5 mg/L in storm composite samples. Median concentrations were 0.88 mg/L in base-flow samples and 1.2 mg/L in storm composite samples. At the Ursina station, concentrations of total nitrogen ranged from 0.25 to 0.92 mg/L in base-flow samples; the median concentration was 0.57 mg/L. The estimated total nitrogen load at the Bakersville station was 262 pounds (lb) for 11 months of the 2010 water year (November 2009 to September 2010) and 266 lb for the 2011 water year. Most of the total

  13. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV


    University Press, xiv + 299 pp. [Yale Southeast Asia studies monograph 48.] 1999 -Bernice de Jong Boers, Peter Just, Dou Donggo justice; Conflict and morality in an Indonesian society. Lanham, Maryland: Rowman and Littlefield, 2001, xi + 263 pp. -Nico J.G. Kaptein, Howard M. Federspiel, Islam and ideology in the emerging Indonesian state; The Persatuan Islam (PERSIS, 1923 to 1957. Leiden: Brill, 2001, xii + 365 pp. -Gerrit Knaap, Els M. Jacobs, Koopman in Azië; De handel van de Verenigde Oost-Indische Compagnie tijdens de 18de eeuw. Zutphen: Walburg Pers, 2000, 304 pp. -Toon van Meijl, Bruce M. Knauft, From primitive to postcolonial in Melanesia and anthropology. Ann Arbor: University of Michigan Press, 1999, x + 320 pp. -Jennifer Nourse, Juliette Koning ,Women and households in Indonesia; Cultural notions and social practices. Richmond, Surrey: Curzon, 2000, xiii + 354 pp., Marleen Nolten, Janet Rodenburg (eds -Sandra Pannell, Clayton Fredericksen ,Altered states; Material culture transformations in the Arafura region. Darwin: Northern Territory University Press, 2001, xiv + 160 pp., Ian Walters (eds -Anne Sofie Roald, Alijah Gordon, The propagation of Islam in the Indonesian-Malay archipelago. Kuala Lumpur: Malaysian sociological research institute, 2001, xxv + 472 pp. -M.J.C. Schouten, Mary Taylor Huber ,Gendered missions; Women and men in missionary discourse and practice. Ann Arbor: The University of Michigan Press, 1999, x + 252 pp., Nancy C. Lutkehaus (eds -Karel Steenbrink, Nakamura Mitsuo ,Islam and civil society in Southeast Asia. Singapore: Institute of Southeast Asian studies, 2001, 211 pp., Sharon Siddique, Omar Farouk Bajunid (eds -Heather Sutherland, Robert Cribb, Historical atlas of Indonesia, Richmond, Surrey: Curzon, 2000, x + 256 pp. -Sikko Visscher, Lee Kam Hing ,The Chinese in Malaysia. Kuala Lumpur: Oxford University Press, 2000, xxix + 418 pp., Tan Chee-Beng (eds -Edwin Wieringa, Jane Drakard, A kingdom of words; Language and power in Sumatra. Kuala

  14. Circumstances of falls and falls-related injuries in a cohort of older patients following hospital discharge

    Directory of Open Access Journals (Sweden)

    Hill AM


    Full Text Available Anne-Marie Hill,1 Tammy Hoffmann,2,3 Terry P Haines4,51School of Physiotherapy, Institute for Health Research, The University of Notre Dame Australia, Fremantle, WA, 2Centre for Research in Evidence-Based Practice, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, QLD, 3School of Health and Rehabilitation Sciences, The University of Queensland, 4School of Primary Health Care, Monash University, Melbourne, VIC, 5Allied Health Research Unit, Kingston Centre, Southern Health, Clayton, VIC, AustraliaBackground: Older people are at increased risk of falls after hospital discharge. This study aimed to describe the circumstances of falls in the six months after hospital discharge and to identify factors associated with the time and location of these falls.Methods: Participants in this randomized controlled study comprised fallers (n = 138 who were part of a prospective observational cohort (n = 343 nested within a randomized controlled trial (n = 1206. The study tested patient education on falls prevention in hospital compared with usual care in older patients who were discharged from hospital and followed for six months after hospital discharge. The outcome measures were number of falls, falls-related injuries, and the circumstances of the falls, measured by use of a diary and a monthly telephone call to each participant.Results: Participants (mean age 80.3 ± 8.7 years reported 276 falls, of which 150 (54.3% were injurious. Of the 255 falls for which there were data available about circumstances, 190 (74.5% occurred indoors and 65 (25.5% occurred in the external home environment or wider community. The most frequent time reported for falls was the morning (between 6 am and 10 am when 79 (28.6% falls, including 49 (32.7% injurious falls, occurred. The most frequently reported location for falls (n = 80, 29.0%, including injurious falls (n = 42, 28.0%, was the bedroom. Factors associated with falling in the bedroom included

  15. Fire occurrence prediction in the Mediterranean: Application to Southern France (United States)

    Papakosta, Panagiota; Öster, Jan; Scherb, Anke; Straub, Daniel


    the German and French Weather Services (Deutscher Wetterdienst and Météo-France). Historical fire events are taken from Prométhée database. Time series 2000-2010 are used as learning data and data from 2011 is used as the validation data. The resulting model can support real-time fire risk estimation for improved allocation of firefighting resources and planning of other mitigation actions. [1] Keeley, J.E.; Bond, W.J.; Bradstock, R.A.; Pausas, J.G.; Rundel, P.W. (2012): Fire in Mediterranean ecosystems: ecology, evolution and management. Cambridge University Press, New York, USA, pp.515 [2] Lawson, B.D.; Armitage, O.B. (2008): Weather Guide for the Canadian Forest Fire Danger Rating System. Natural Resources Canada, Canadian Forest Service, Northern Forestry Centre, Edmonton, Alberta, Canada. [3] Van Wagner, C.E.; Pickett, T.L. (1985): Equations and FORTRAN Program for the Canadian Forest Fire Weather Index System. Forestry Technical Report 33. Canadian Forestry Service, Government of Canada, Ottawa, Ontario, Canada [4] Syphard, A.D.; Radeloff, V.C.; Keuler, N.S.; Taylor, R.S.; Hawbaker, T.J.; Stewart, S.I.; Clayton, M.K. (2008): Predicting spatial patterns of fire on a southern California landscape. International Journal of Wildland Fire, 17, pp.602-613 [5] Papakosta, P.; Klein, F.; König, S.; Straub, D. (2012): Linking spatio-temporal data to the Fire Weather Index to estimate the probability of wildfire in the Mediterranean. Geophysical Research Abstracts, Vol.14, EGU2012-12737, EGU General Assembly 2012

  16. Developing reciprocity, intercultural communicative competence, and content learning through international service learning


    VILBER, Aurelio; MALAQUE, Cherry; MONSANTO, Kayumangi; GUMALAL, Jeraline; Lou ALLEGO, Ivan; オレリオ, ビルバー; チェリー, マラケー; カユマンギ, マンサント; シェラリン, グムラン; アイバン, ルー・アルゴ



  17. Products of the Strecker Synthesis as Indicators of Parent Body Conditions of the Murchison Meteorite (United States)

    Lerner, Narcinda R.; Cooper, George W.; Chang, Sherwood (Technical Monitor)


    found on Murchison and the rock to water ratio estimated by Clayton and Mayeda (1984). The cyanide concentration was that estimated by Peltzer et al. (1984). The ammonia concentration and pH were varied. We studied these mixtures at 298 K and 263 K. We found that high relative abundances of AIBA were produced at 263 K but not at 298 K. We only produced a-methyl a-amino hydroxy acids at 263 K with no initial ammonia. The abundances of a-amino acids, a-hydroxy acids and imino acids found on Murchison are consistent with a Strecker synthesis which took place at low temperature and with a low concentration of ammonia.

  18. Current and future initiatives for vascular health management in clinical practice

    Directory of Open Access Journals (Sweden)

    Cameron JD


    Full Text Available James D Cameron,1 Roland Asmar,2 Harry Struijker-Boudier,3 Kohji Shirai,4 Yuriy Sirenko,5 Yulia Kotovskaya,6 Jirar Topouchian71Monash Cardiovascular Research Centre, Clayton, Melbourne, Victoria, Australia; 2Roland Asmar, Foundation Medical Research Institutes, Paris, France; 3Department of Pharmacology, Maastricht University, Maastricht, The Netherlands; 4Department of Vascular Function, Sakura Hospital, Toho University, Tokyo, Japan; 5Institute of Cardiology, Kiev, Ukraine; 6ESH Hypertension Excellence Center of Peoples Friendship University of Russia, Moscow, Russia; 7Department of Diagnosis and Therapeutics, Hôtel-Dieu University Hospital, Paris, FranceAbstract: Central arterial structure and function comprise a primary determinant of vascular health, and are integral to the important concept of ventriculo-vascular coupling or interaction. Central aortic stiffening is a major influence on central blood pressure, and directly relates to coronary perfusion. The joint session of the International Society of Vascular Health (Eastern Region and the Ukrainian Congress of Cardiology was held in Kiev, Ukraine, on September 23, 2011; it provided an expert forum to discuss arterial evaluations, clinical applications, and progress toward translating arterial protection into cardiovascular benefits. The conclusions of the expert panel were:1. Aortic stiffness is not presently a treatment target but may be useful for substratifying cardiovascular risk in individuals in order to better target the intensity of conventional therapy, and it may be useful in assessing response to treatment.2. Crosstalk between macro- and microcirculation in hypertension has important implications for pharmacological treatment. An antihypertensive regimen should abolish the vicious cycle between the increased resistance in the microcirculation and the increased stiffness of the larger arteries. Such treatment should be based on drugs with multiple actions on the vascular tree

  19. EAARL coastal topography-western Florida, post-Hurricane Charley, 2004: seamless (bare earth and submerged. (United States)

    Nayegandhi, Amar; Bonisteel, Jamie M.; Wright, C. Wayne; Sallenger, A.H.; Brock, John C.; Yates, Xan


    processed using the Airborne Lidar Processing System (ALPS), a custom-built processing system developed in a NASA-USGS collaboration. ALPS supports the exploration and processing of lidar data in an interactive or batch mode. Modules for presurvey flight-line definition, flight-path plotting, lidar raster and waveform investigation, and digital camera image playback have been developed. Processing algorithms have been developed to extract the range to the first and last significant return within each waveform. ALPS is used routinely to create maps that represent submerged or sub-aerial topography. Specialized filtering algorithms have been implemented to determine the 'bare earth' under vegetation. For more information about similar projects, please visit the Decision Support for Coastal Science and Management website. Selected References Brock, J.C., Wright, C.W., Sallenger, A.H., Krabill, W.B., and Swift, R.N., 2002, Basis and methods of NASA airborne topographic mapper Lidar surveys for coastal studies: Journal of Coastal Research, v. 18, no. 1, p. 1-13. Crane, Michael, Clayton, Tonya, Raabe, Ellen, Stoker, Jason, Handley, Larry, Bawden, Gerald, Morgan, Karen, and Queija, Vivian, 2004, Report of the U.S. Geological Survey Lidar workshop sponsored by the Land Remote Sensing Program and held in St. Petersburg, FL, November 2002: U.S. Geological Survey Open-File Report 2004-1456, 72 p. Nayegandhi, Amar, Brock, J.C., and Wright, C.W., 2009, Small-footprint, waveform-resolving Lidar estimation of submerged and sub-canopy topography in coastal environments: International Journal of Remote Sensing, v. 30, no. 4, p. 861-878. Sallenger, A.H., Wright, C.W., and Lillycrop, Jeff, 2005, Coastal impacts of the 2004 hurricanes measured with airborne Lidar; initial results: Shore and Beach, v. 73, nos. 2-3, p. 10-14. Resources Included Readme.txt File

  20. Lipid Biomarkers of the Maquoketa Formation, Iowa: Transect of a Paleobathymetry Gradient in the Lead-Up to the Late Ordovician Mass Extinction (United States)

    Rohrssen, M.; Love, G. D.


    The Late Ordovician (~450-44 Ma) was a period of drastic environmental change, beginning in a hothouse climate with epeiric seaways near a Phanerozoic high and concluding with the Hirnantian glaciation, large positive carbon isotope excursion(s) (Hirnantian isotopic carbon excursion, HICE) and one of the Big Five mass extinctions. The two-phased expression of the Late Ordovician mass extinction has been attributed to regression-driven habitat loss and the consequences of cooling climate, followed by transgression of oxygen-deficient bottom water onto previously oxygenated shelves. Lipid biomarker records indicate substantial changes in microbial communities during the glacial maximum and mass extinction (Rohrssen et al., in press); to fully uncouple the effects of sea level-driven facies change from more regional or global factors we have analyzed lipid biomarkers along a shallow to deep water paleobathymetry gradient in central Laurentia across a transgressive-regressive cycle. We compare results from the Maquoketa Formation to previous work on Hirnantian- and Katian-age rocks to develop a better understanding of the association of microbial communities with Late Ordovician-age epeiric sea and upwelling environments. During deposition of the Katian-age Maquoketa Formation, Iowa was bounded to the north by exposed highlands of the Transcontinental Arch and separated from the southeastern half of the Laurentian epeiric seaway by a northeast-southwest trending shelf-break into the deeper waters of the Seebree Trough, a depression thought to have connected central and eastern Laurentia to the open ocean. As a result of this paleotopography, samples of the Maquoketa Formation collected from drill cores BS5 (Clayton County), SS-15 (Jackson County), and H33 (Des Moines County) in a transect from northeastern to southeastern Iowa capture the change in facies from carbonate-rich platform to shale with phosphatic intervals at the shelf-break in contemporaneous deposits

  1. Editorial: Focus on Laser- and Beam-Driven Plasma Accelerators (United States)

    Joshi, Chan; Malka, Victor


    The ability of short but intense laser pulses to generate high-energy electrons and ions from gaseous and solid targets has been well known since the early days of the laser fusion program. However, during the past decade there has been an explosion of experimental and theoretical activity in this area of laser-matter interaction, driven by the prospect of realizing table-top plasma accelerators for research, medical and industrial uses, and also relatively small and inexpensive plasma accelerators for high-energy physics at the frontier of particle physics. In this focus issue on laser- and beam-driven plasma accelerators, the latest advances in this field are described. Focus on Laser- and Beam-Driven Plasma Accelerators Contents Slow wave plasma structures for direct electron acceleration B D Layer, J P Palastro, A G York, T M Antonsen and H M Milchberg Cold injection for electron wakefield acceleration X Davoine, A Beck, A Lifschitz, V Malka and E Lefebvre Enhanced proton flux in the MeV range by defocused laser irradiation J S Green, D C Carroll, C Brenner, B Dromey, P S Foster, S Kar, Y T Li, K Markey, P McKenna, D Neely, A P L Robinson, M J V Streeter, M Tolley, C-G Wahlström, M H Xu and M Zepf Dose-dependent biological damage of tumour cells by laser-accelerated proton beams S D Kraft, C Richter, K Zeil, M Baumann, E Beyreuther, S Bock, M Bussmann, T E Cowan, Y Dammene, W Enghardt, U Helbig, L Karsch, T Kluge, L Laschinsky, E Lessmann, J Metzkes, D Naumburger, R Sauerbrey, M. Scḧrer, M Sobiella, J Woithe, U Schramm and J Pawelke The optimum plasma density for plasma wakefield excitation in the blowout regime W Lu, W An, M Zhou, C Joshi, C Huang and W B Mori Plasma wakefield acceleration experiments at FACET M J Hogan, T O Raubenheimer, A Seryi, P Muggli, T Katsouleas, C Huang, W Lu, W An, K A Marsh, W B Mori, C E Clayton and C Joshi Electron trapping and acceleration on a downward density ramp: a two-stage approach R M G M Trines, R Bingham, Z Najmudin

  2. A Nitrogen-concentrated Phase in IA Iron Meteorite Acid Residue (United States)

    Hashizume, K.; Sugiura, N.


    portion of nitrogen is released at 500 degrees C and 600 degrees C temperature fractions. Total nitrogen amounts and average delta^l5N values of the two acid residues are described in Table 1. Discussion and Summary: Sample "Can-1bn" is 3-4 times concentrated in nitrogen than "Call-2b," although its delta^15N value is within terrestrial range (0 < delta^15N < +20 per mil). Presently, we cannot deny the possibility that nitrogen in "Can-1bn" is dominated by terrestrial nitrogen, which may have been acquired during the acid treatment. Nevertheless, nitrogen isotope data of "Can-2b" suggests that indigenous nitrogen is indeed concentrated in the acid residue of Canyon Diablo. Bulk nitrogen isotope data of Canyon Diablo is reported to be delta^15N= -61.8 +- 10.4 per mil, N= 38.0 +- 155 ppm [2]. Therefore, delta^15N values of "Can-2b" can be resulted by a mixing of indigenous nitrogen and contaminating nitrogen. However, distinct delta^15N values of these two samples may indicate, in turn, that nitrogen isotopes in inclusions of Canyon Diablo are truly heterogeneous because carbon isotopes of graphite inclusions in IA iron meteorites seem to be heterogeneous [7]. Acknowledgments: We thank Dr. J.-I. Matsuda of Osaka University for providing samples and information on these samples. References: [1] Scott E. R. D. and Wasson J. T. (1975) Rev. Geophys. Space Sci., 13, 527-546. [2] Prombo C. A. and Clayton R. N. (1983) Meteoritics, 18, 377-379. [3] Franchi I. A. et al. (1988) Meteoritics, 22, 379-380. [4] Hashizume K. (1993) Doctor Thesis. [5] Murty S. V. S. et al. (1983) GCA, 47, 1061-1068. [6] Ogata Y. et al. (1990) In Abstract of the 1990 Annual Meeting of the Geochemical Society of Japan, 57. [7] Deines P. and Wickman F. E. (1973) GCA, 37, 1295-1319. Table 1 appears here in the hard copy.

  3. Isotopic records in CM hibonites: Implications for timescales of mixing of isotope reservoirs in the solar nebula (United States)

    Liu, Ming-Chang; McKeegan, Kevin D.; Goswami, Jitendra N.; Marhas, Kuljeet K.; Sahijpal, Sandeep; Ireland, Trevor R.; Davis, Andrew M.


    10Be observed in CAIs must be produced by irradiation of precursor solids in the early solar system. The lack of 26Al in PLAC hibonites indicates that significant amounts of 26Al were not formed in the same spallogenic processes that made 10Be in PLAC precursors. This is most easily understood as indicating very early formation of the PLAC hibonites, prior to the incorporation and mixing of 26Al into the solar nebula, although an alternative scenario, which invokes irradiation under different solar flare conditions, cannot be ruled out. Lithium isotopes are normal within uncertainties, probably reflecting contamination and/or postcrystallization exchange. The oxygen isotopic compositions of SHIBs and PLACs are all highly 16O-enriched, but are not derived from a homogeneous reservoir: Δ 17O values span a range of ˜-28‰ to -15‰. The ranges of 16O-enrichment in SHIBs and PLACs overlap and are less "anomalous" than the most 16O-enriched compositions found in meteorites [Kobayashi S., Imai H. and Yurimoto H. (2003) New extreme 16O-rich chondrule in the early solar system. Geochem. J.37, 663-669]. Both PLACs and SHIBs formed in 16O-enriched reservoirs characterized by small-scale heterogeneities in the gas phase. If such heterogeneities were generated by an admixture of relatively 16O-poor gas created by self-shielding during CO photolysis and transported to the hot inner regions of the accretion disk, then this process must have been initiated very early on, prior to the arrival of fresh radioactivity into the inner solar system. Oxygen isotope heterogeneities persisted throughout the formation interval of PLACs, CAI precursors, and SHIBs which could be as long as 3 × 10 5 years based on 26Al records. One SHIB and one BAG exhibit mass fractionated oxygen isotopic compositions similar to those seen in FUN inclusions and in several platy hibonite crystals [Lee T., Mayeda T. K. and Clayton R. N. (1980) Oxygen isotopic anomalies in Allende inclusion HAL. Geophys. Res


    Directory of Open Access Journals (Sweden)

    Selvino José Assmann


    of biopolitics, calling the attention to distinctions and identities between historically different mechanisms of power. The author tries to call the attention to the polissemic character of the notion of biopolitics. In the fourth article, Cláudia Hausman Silveira, doctoral student at the Interdisciplinary Program of Post-Graduation in Human sciences (DICH at the Federal University of Santa Catarina (UFSC, presents the issue of the family health, comparing the models that have inspired the construction of the Program of Family Health in Brazil, observing their differences and similarities. Moreover, she makes a comparative analysis among the Cuban, English, Canadian and Brazilian models, concluding that the Program multiprofessional proposal of work in interdisciplinary teams, in accordance with the Only System of Health (SUS, can assist in the fulfillment of the health law in the country. In the fifth article, the environmental issue is treated under the pedagogical point of view. Clayton Ângelo Silva Costa, Master in Environmental Sciences (UEMG presents results of a research carried through with private school teachers in the city of Contagem, Minas Gerais, showing the obstacles involving the application of the environmental education interdisciplinary project, focusing aspects of the atmospheric pollution. The last article approaches aspects of the Humanitarian International law. Geovane Machado Alves, Master’s Degree student in Public Law from the University of the Vale do Rio dos Sinos (UNISINOS, starts from the concept of solidarity and humanitarian intervention, and questions the Brazilian performance in Haiti as well as the legal paradigm of the international solidarism and its repercussions. Closing this issue, the theme is the public university itself and its current impasses and challenges. Héctor Ricardo Leis, PhD in Philosophy from the PUC-RJ, associated professor of the Sociology Department, and Selvino J. Assmann, PhD in Philosophy from the

  5. Trading forests for yields in the Peruvian Amazon (United States)

    Gibbs, Holly


    inhabited and often have contested land tenure. We must carefully consider our consumption of these commodities in the face of growing land scarcity (Lambin and Meyfroidt 2011). If high-yield plantations displace low-yield plantations they too may follow the path of industrial agriculture and resume destruction of the forests that conservation efforts aim to protect. Without clear incentives to spare land, we could be trading forest for higher yields. References Angelsen A and Kaimowitz D 2001 Agricultural Technologies and Tropical Deforestation (New York: CABI Publishing) ( files/books/bangelsen0101e0.pdf) Butler R and Laurance W 2010 Is oil palm the next emerging threat to the Amazon? Trop. Conserv. Sci. 2 1-10 Gibbs H K, Johnston M, Foley J A, Holloway T, Monfreda C, Ramankutty N and Zaks D 2008 Carbon payback times for crop-based biofuel expansion in the tropics: the effects of changing yield and technology Environ. Res. Lett. 3 034001 Gibbs H K, Ruesch A S, Achard F, Clayton M K, Holmgren P, Ramankutty N and Foley J A 2010 Tropical forests were the primary sources of new agricultural land in the 1980s and 1990s Proc. Natl Acad. Sci. 107 16732-7 Gutiérrez-Vélez V H, DeFries R, Pinedo-Vásquez M, Uriarte M, Padoch C, Baethgen W, Fernandes K and Lim Y 2011 High-yield oil palm expansion spares land at the expense of forests in the Peruvian Amazon Environ. Res. Lett. 6 044029 Koh L and Wilcove D 2008 Is oil palm agriculture really destroying tropical biodiversity? Conserv. Lett. 1 60-4 Lambin E and Meyfroidt P 2011 Inaugural article: global land use change, economic globalization, and the looming land scarcity Proc. Natl Acad. Sci. 108 93465-72 Morton D C et al 2006 Cropland expansion changes deforestation dynamics in the southern Brazilian Amazon Proc. Natl Acad. Sci. USA 103 14637-41

  6. Geology and ground water resources of Montgomery County, Alabama (United States)

    Knowles, Doyle Blewer; Reade, H.L.; Scott, J.C.


    Montgomery County includes an area of 790 square miles in east-central Alabama. The economy of Montgomery County is related primarily to the growing and processing of agricultural products. The county is in the northern part of the Coastal Plain. It consists of parts of four divisions of the Coastal Plain: the terraces, the Black Prairie, the Chunnennuggee Hills, and the flood plains. The county drains north and northwest into the Alabama and Tallapoosa Rivers, except for a small area in the southern part of the county that is drained by tributaries of the Conecuh River. Sedimentary rocks of Late Cretaceous age underlie Montgomery County. They are divided, in ascending order, into the following: Coker and Gordo formations of the Tuscaloosa group; Eutaw formation; and Mooreville and Demopolis chalks, Ripley formation, Prairie Bluff chalk, and Providence sand of the Selma group. The Clayton formation of Tertiary age crops out in a small area in the southern part of the county. Pleistocene terrace deposits of the ancestral Alabama River overlie the older rocks in the northern part of the county. Recent alluvium underlies the flood plains of the larger streams. The Cretaceous and younger rocks consist chiefly of clay, chalk, sandstone, sand, and gravel, and a few thin beds of limestone. These deposits are underlain by a basement complex of pre-Cretaceous crystalline rocks. Large-scale withdrawals of water began in the Montgomery area about 1885. Pumpage by the city of Montgomery in 1958 averaged about 15 million gallons per day. It is estimated that an additional 10 to 15 million gallons per day was pumped in the county for industrial, irrigation, domestic, and stock use. The principal aquifer in the country is,the Eutaw formation. It supplies water to the city of Montgomery municipal wells, to industrial wells in the Montgomery area, and to most domestic and stock wells in the northern two-thirds of the county. Irrigation wells also tap the Eutaw. Yields from wells

  7. Role of nucleus accumbens glutamatergic plasticity in drug addiction

    Directory of Open Access Journals (Sweden)

    Quintero GC


    Full Text Available Gabriel C Quintero1–31Florida State University – Panama, Clayton, Panama; 2Medical University of South Carolina, Charleston, South Carolina, USA; 3Smithsonian Tropical Research Institute, Ancon, Republic of PanamaAbstract: Substance dependence is characterized by a group of symptoms, according to the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision (DSM-IV-TR. These symptoms include tolerance, withdrawal, drug consumption for alleviating withdrawal, exaggerated consumption beyond original intention, failure to reduce drug consumption, expending a considerable amount of time obtaining or recovering from the substance’s effects, disregard of basic aspects of life (for example, family, and maintenance of drug consumption, despite facing adverse consequences. The nucleus accumbens (NAc is a brain structure located in the basal forebrain of vertebrates, and it has been the target of addictive drugs. Different neurotransmitter systems at the level of the NAc circuitry have been linked to the different problems of drug addiction, like compulsive use and relapse. The glutamate system has been linked mainly to relapse after drug-seeking extinction. The dopamine system has been linked mainly to compulsive drug use. The glutamate homeostasis hypothesis centers around the dynamics of synaptic and extrasynaptic levels of glutamate, and their impact on circuitry from the prefrontal cortex (PFC to the NAc. After repetitive drug use, deregulation of this homeostasis increases the release of glutamate from the PFC to the NAc during drug relapse. Glial cells also play a fundamental role in this hypothesis; glial cells shape the interactions between the PFC and the NAc by means of altering glutamate levels in synaptic and extrasynaptic spaces. On the other hand, cocaine self-administration and withdrawal increases the surface expression of subunit glutamate receptor 1 (GluA1 of alpha-amino-3-hydroxy-5-methyl-4

  8. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV


    Full Text Available -Martin Baier, Han Knapen, Forests of fortune?; The environmental history of Southeast Borneo, 1600-1880. Leiden: The KITLV Press, 2001, xiv + 487 pp. [Verhandelingen 189] -Jean-Pascal Bassino, Per Ronnas ,Entrepreneurship in Vietnam; Transformations and dynamics. Copenhagen: Nordic Institute of Asian Studies (NIAS and Singapore: Institute of Southeast Asian Studies, 2001, xii + 354 pp., Bhargavi Ramamurty (eds -Adriaan Bedner, Renske Biezeveld, Between individualism and mutual help; Social security and natural resources in a Minangkabau village. Delft: Eburon, 2001, xi + 307 pp. -Linda Rae Bennett, Alison Murray, Pink fits; Sex, subcultures and discourses in the Asia-Pacific. Clayton, Victoria: Monash Asia Institute, 2001, xii + 198 pp. [Monash Papers on Southeast Asia 53.] -Peter Boomgaard, Laurence Monnais-Rousselot, Médecine et colonisation; L'aventure indochinoise 1860-1939. Paris: CNRS Editions, 1999, 489 pp. -Ian Coxhead, Yujiro Hayami ,A rice village saga; Three decades of Green revolution in the Philippines. Houndmills, Basingstoke: MacMillan, 2000, xviii + 274 pp., Masao Kikuchi (eds -Robert Cribb, Frans Hüsken ,Violence and vengeance; Discontent and conflict in New Order Indonesia. Saarbrücken: Verlag für Entwicklungspolitik, 2002, 163 pp. [Nijmegen Studies in Development and Cultural Change 37.], Huub de Jonge (eds -Frank Dhont, Michael Leifer, Asian nationalism. London: Routledge, 2000, x + 210 pp. -David van Duuren, Joseph Fischer ,The folk art of Bali; The narrative tradition. Kuala Lumpur: Oxford University Press, 1998, xx + 116 pp., Thomas Cooper (eds -Cassandra Green, David J. Stuart-Fox, Pura Besakih; Temple, religion and society in Bali. Leiden: KITLV Press, xvii + 470 pp. [Verhandelingen 193.] -Hans Hägerdal, Vladimir I. Braginsky ,Images of Nusantara in Russian literature. Leiden: KITLV Press, 1999, xxvi + 516 pp., Elena M. Diakonova (eds -Hans Hägerdal, David Chandler, A history of Cambodia (third edition. Boulder

  9. Book Reviews

    Directory of Open Access Journals (Sweden)

    ? Parakitri


    , Culture and language development, Studies in the social and cultural foundations of language No. 6, Cambridge University Press, 227 + 10 pp. - Denis Monnerie, Frederick H. Damon, Death rituals and life in the societies of the Kula Ring, Dekalb: Northern Illinois University Press, 1989. 280 pp., maps, figs., bibliogr., Roy Wagner (eds. - Denis Monnerie, Frederick H. Damon, From Muyuw to the Trobriands; Transformations along the northern side of the Kula ring, Tucson: The University of Arizona Press, 1990. xvi + 285 pp., maps, figs., illus., apps., bibliogr., index. - David S. Moyer, Jeremy Boissevain, Dutch dilemmas; Anthropologists look at the Netherlands, Assen/Maastricht: Van Gorcum, 1989, v + 186 pp., Jojada Verrips (eds. - Gert Oostindie, B.H. Slicher van Bath, Indianen en Spanjaarden; Een ontmoeting tussen twee werelden, Latijns Amerika 1500-1800. Amsterdam: Bert Bakker, 1989. 301 pp. - Parakitri, C.A.M. de Jong, Kompas 1965-1985; Een algemene krant met een katholieke achtergrond binnen het religieus pluralisme van Indonesie, Kampen: Kok, 1990. - C.A. van Peursen, J. van Baal, Mysterie als openbaring. Utrecht: ISOR, 1990. - Harry A. Poeze, R.A. Longmire, Soviet relations with South-East Asia; An historical survey. London-New York: Kegan Paul International, 1989, x + 176 pp. - Harry A. Poeze, Ann Swift, The road to Madiun; The Indonesian communist uprising of 1948. Ithaca, N.Y.: Cornell Modern Indonesia Project (Monograph series 69, 1989, xii + 116 pp. - Alex van Stipriaan, Cornelis Ch. Goslinga, The Dutch in the Caribbean and in Surinam 1791/5 - 1942, Assen/Maastricht: Van Gorcum, 1990. xii + 812 pp. - A. Teeuw, Keith Foulcher, Social commitment in literature and the arts: The Indonesian ‘Institute of People’s culture’ 1950-1965, Clayton, Victoria: Southeast Asian studies, Monash University (Centre of Southeast Asian studies, 1986, vii + 234 pp. - Elly Touwen-Bouwsma, T. Friend, The blue-eyed enemy; Japan against the West in Java and Luzon, 1942-1945. New

  10. Rubitecan: 9-NC, 9-Nitro-20(S)-camptothecin, 9-nitro-camptothecin, 9-nitrocamptothecin, RFS 2000, RFS2000. (United States)


    similar to the one at the centre of rubitecan. In addition, SuperGen was also issued US patent No. 6,485,514 in December 2002, covering the local delivery of rubitecan via stents and/or catheters to sites of proliferating cells. Stent- or catheter-delivered rubitecan may be beneficial in certain types of cardiac procedures, such as ablation or angioplasty, as well as for direct injection into a certain number of solid tumours. SuperGen is also developing an inhaled, liposomal formulation of rubitecan. It acquired the worldwide rights to this formulation from the Clayton Foundation in December 1999. Inhaled rubitecan is in clinical trials in the US for the treatment of lung cancer and pulmonary metastatic cancer. Copyright 2004 Adis Data Information BV

  11. Heavy Element Staining of Sedimentary Organic Matter Functional Groups for Backscattered Electron Imaging Marquage par éléments lourds de la matière organique sédimentaire pour la microscopie électronique en électrons rétrodiffusés

    Directory of Open Access Journals (Sweden)

    Belin-Geindre S.


    , 1992. Son imagerie est basée sur les contrastes de numéro atomique (Z existant entre les divers constituants. La matière organique apparaît noire et les minéraux gris. Cependant il n'est pas possible de distinguer plusieurs types de matière organique avec le MEB/ER. Afin de mettre en évidence des contrastes au MEB/ER entre différentes matières organiques, les échantillons ont été marqués par des éléments lourds qui ont la particularité de se fixer de manière sélective et spécifique sur les groupes fonctionnels. Cette méthode est largement employée par la biologie cellulaire pour révéler divers corps organiques (Soligo et Lambertenghi-Deliliers, 1987; Langsdorff et al. , 1990; Clark, 1991; Namimatsu, 1992 ou bien par la science des matériaux dans le domaine des polymères (Sawyer et Grubb, 1987; Ohlsson et Törnell, 1990; Sue et al. , 1991; Janik et al. , 1992. L'application à la géologie et à la pétrographie est restée jusqu'à présent assez réduite : sédiments argileux (Whitlatch et Johnson, 1974; Green et al. , 1979; Bishop et al. , 1992; Hillier et Clayton, 1992, charbons (Corcoran et Stephens, 1987; Sommerfeld et al. , 1992, sols (Foster, 1981. Les éléments lourds utilisés pour le marquage sont très variés et présentent une spécificité plus ou moins large (Reynolds, 1963; Lewis et Knight, 1976; Takeuchi et Takeuchi, 1990. La matière organique sédimentaire est un mélange complexe de macromolécules dont la composition dépend de la nature de la matière organique originelle et de son degré d'évolution (Tissot et Welte, 1984. La matière organique peu évoluée possède de nombreuses variétés de groupes fonctionnels (Rouxhet et al. , 1980; Béhar et Vandenbroucke, 1987. La faisabilité de la méthode a d'abord été testée sur des polymères contenant des fonctions chimiques susceptibles d'exister dans les kérogènes naturels (tableau 1. Puis elle a été appliquée à des sédiments presque exclusivement formés de

  12. Personal Exposure to Mixtures of Volatile Organic Compounds: Modeling and Further Analysis of the RIOPA Data (United States)

    Batterman, Stuart; Su, Feng-Chiao; Li, Shi; Mukherjee, Bhramar; Jia, Chunrong


    semi-parametric Dirichlet process mixture (DPM) of normal distributions for three individual VOCs (chloroform, 1,4-DCB, and styrene). Goodness of fit for these full distribution models was also evaluated using simulated data. Specific Aim 2 Mixtures in the RIOPA VOC data set were identified using positive matrix factorization (PMF) and by toxicologic mode of action. Dependency structures of a mixture’s components were examined using mixture fractions and were modeled using copulas, which address correlations of multiple components across their entire distributions. Five candidate copulas (Gaussian, t, Gumbel, Clayton, and Frank) were evaluated, and the performance of fitted models was evaluated using simulation and mixture fractions. Cumulative cancer risks were calculated for mixtures, and results from copulas and multivariate lognormal models were compared with risks based on RIOPA observations. Specific Aim 3 Exposure determinants were identified using stepwise regressions and linear mixed-effects models (LMMs). RESULTS Specific Aim 1 Extreme value exposures in RIOPA typically were best fitted by three-parameter generalized extreme value (GEV) distributions, and sometimes by the two-parameter Gumbel distribution. In contrast, lognormal distributions significantly underestimated both the level and likelihood of extreme values. Among the VOCs measured in RIOPA, 1,4-dichlorobenzene (1,4-DCB) was associated with the greatest cancer risks; for example, for the highest 10% of measurements of 1,4-DCB, all individuals had risk levels above 10−4, and 13% of all participants had risk levels above 10−2. Of the full-distribution models, the finite mixture of normal distributions with two to four clusters and the DPM of normal distributions had superior performance in comparison with the lognormal models. DPM distributions provided slightly better fit than the finite mixture distributions; the advantages of the DPM model were avoiding certain convergence issues associated

  13. Personal exposure to mixtures of volatile organic compounds: modeling and further analysis of the RIOPA data. (United States)

    Batterman, Stuart; Su, Feng-Chiao; Li, Shi; Mukherjee, Bhramar; Jia, Chunrong


    -parametric Dirichlet process mixture (DPM) of normal distributions for three individual VOCs (chloroform, 1,4-DCB, and styrene). Goodness of fit for these full distribution models was also evaluated using simulated data. Specific Aim 2. Mixtures in the RIOPA VOC data set were identified using positive matrix factorization (PMF) and by toxicologic mode of action. Dependency structures of a mixture's components were examined using mixture fractions and were modeled using copulas, which address correlations of multiple components across their entire distributions. Five candidate copulas (Gaussian, t, Gumbel, Clayton, and Frank) were evaluated, and the performance of fitted models was evaluated using simulation and mixture fractions. Cumulative cancer risks were calculated for mixtures, and results from copulas and multivariate lognormal models were compared with risks based on RIOPA observations. Specific Aim 3. Exposure determinants were identified using stepwise regressions and linear mixed-effects models (LMMs). Specific Aim 1. Extreme value exposures in RIOPA typically were best fitted by three-parameter generalized extreme value (GEV) distributions, and sometimes by the two-parameter Gumbel distribution. In contrast, lognormal distributions significantly underestimated both the level and likelihood of extreme values. Among the VOCs measured in RIOPA, 1,4-dichlorobenzene (1,4-DCB) was associated with the greatest cancer risks; for example, for the highest 10% of measurements of 1,4-DCB, all individuals had risk levels above 10(-4), and 13% of all participants had risk levels above 10(-2). Of the full-distribution models, the finite mixture of normal distributions with two to four clusters and the DPM of normal distributions had superior performance in comparison with the lognormal models. DPM distributions provided slightly better fit than the finite mixture distributions; the advantages of the DPM model were avoiding certain convergence issues associated with the finite mixture

  14. Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017; Venice (Italy; October 31-November 4, 2017; Session "Neurology and Follow-up"

    Directory of Open Access Journals (Sweden)

    --- Various Authors