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Sample records for william mark armstrong

  1. Welcome Donald Trump, Baltics! The presidency to endure? / Mark Hertling, William E. Pomeranz ; intervjueeris Linas Jegelevicius

    Index Scriptorium Estoniae

    Hertling, Mark

    2017-01-01

    USA Euroopa vägede endine ülem kindralleitnant Mark Hertlingi ja Kennani Instituudi asedirektor William E. Pomeranz analüüsivad Ameerika Ühendriikide uue presidendi Tonald Trumpi ametisseasumise võimalikku mõju Balti riikide julgeolekule

  2. Karen Armstrong

    NARCIS (Netherlands)

    Jansen, J.J.G.

    2005-01-01

    Wie is die Karen Armstrong, wier boeken over de hele wereld bestsellers zijn, maar die nergens zo goed verkoopt als in Nederland? Zij is een van de weinige denkers/schrijvers in onze tijd die beseft hoe belangrijk godsdienst in het leven van mensen zijn kan. Dat maakt haar wereldwijd tot een

  3. Karen Armstrong

    NARCIS (Netherlands)

    Jansen, J.J.G.

    2005-01-01

    Karen Armstrong is wereldwijd een van de meest gelezen moderne auteurs over godsdienst. In Nederland is haar populariteit groot. Haar laatste boek, De grote transformatie, is zelfs eerder in het Nederlands verschenen dan in Engeland en Amerika in het Engels. Het succes van haar boeken bewijst dat

  4. Contrast-Marking Prosodic Emphasis in Williams Syndrome: Results of Detailed Phonetic Analysis

    Science.gov (United States)

    Ito, Kiwako; Martens, Marilee A.

    2017-01-01

    Background: Past reports on the speech production of individuals with Williams syndrome (WS) suggest that their prosody is anomalous and may lead to challenges in spoken communication. While existing prosodic assessments confirm that individuals with WS fail to use prosodic emphasis to express contrast, those reports typically lack detailed…

  5. NASA Armstrong Status

    Science.gov (United States)

    Jacobson, Steven R.

    2014-01-01

    Armstrong (formerly Dryden) Flight Research Center continues it's legacy of exciting work in the area of dynamics and control of advanced vehicle concepts. This status presentation highlights the research and technology development that Armstrong's Control and Dynamics branch is performing in the areas of Control of Flexible Structures and Automated Cooperative Trajectories.

  6. Sequentially and alternatively developed heights for two representative bench marks: near Palmdale, California and along the Bill Williams River, Arizona

    Science.gov (United States)

    Gilmore, Thomas D.; Elliot, Michael R.

    1985-01-01

    This report consists chiefly of 41 tables that both describe and fully document the reconstructions of a series of alternately developed heights based on levelings leading into two representative bench marks in the southwestern United States. One of these marks, 3219, Vincent, California (fig. 1), lies within the area of the Pacific-North American plate boundary; the other, 22Q, Bill Williams River, Arizona (fig. 1), falls within what is believed to be a singularly stable section of southwestern Arizona. Because the levelings that produced these heights were characterized by especially disparate routes with respect to both terrain and climate, the resulting heights provide a test for the existence and magnitude of path-dependent error in geodetic leveling. These two marks were chosen both because of their relative stability with respect to adjacent marks and because their tectonic stability (or instability) can be inferred from the geologic record. Specifically, we can reasonably speculate that 3219 may have sustained measurably significant tectonic displacements during the 20th century, whereas 22Q probably has remained virtually invariant with respect to any fixed datum during the same period. Bench mark 3219 is a standard Geological Survey iron post stamped "3219" near the Southern Pacific Railroad station at Vincent (U.S. Geological Survey, 1898, p. 392); 22Q is a brass cap stamped "22Q (MWD)" set in a concrete post located in a gully immediately north of the Bill Williams River, Arizona (USC&GS Quad. 34114). 3219 was established by the Geological Survey no later than 1897 (Gannett and Baldwin, 1907, p. 365); 22Q was established by the Metropolitan Water District of southern California in advance of the 1931 control surveys along the projected route of the Colorado River Aqueduct.

  7. Armstrong's Building 703 in Palmdale

    Data.gov (United States)

    Federal Laboratory Consortium — NASA Armstrong Flight Research Center's (AFRC) Building 703 is located in Palmdale, Calif., 70 miles northeast of downtown Los Angeles. NASA has leased the facility,...

  8. The Armstrong experiment revisited

    Science.gov (United States)

    Fuchs, Elmar C.; Wexler, Adam D.; Paulitsch-Fuchs, Astrid H.; Agostinho, Luewton L. F.; Yntema, Doekle; Woisetschläger, Jakob

    2014-04-01

    When a high-voltage direct-current is applied to two beakers filled with water or polar liquid dielectrica, a horizontal bridge forms between the two beakers. This experiment was first carried out by Lord Armstrong in 1893 and then forgotten until recently. Such bridges are stable by the action of electrohydrodynamic (EHD) forces caused by electric field gradients counteracting gravity. Due to these gradients a permanent pumping of liquid from one beaker into the other is observed. At macroscopic scale several of the properties of a horizontal water bridge can be explained by modern electrohydrodynamics, analyzing the motion of fluids in electric fields. Whereas on the molecular scale water can be described by quantum mechanics, there is a conceptual gap at mesoscopic scale which is bridged by a number of theories including quantum mechanical entanglement and coherent structures in water - theories that we discuss here. Much of the phenomenon is already understood, but even more can still be learned from it, since such "floating" liquid bridges resemble a small high voltage laboratory of their own: The physics of liquids in electric fields of some kV/cm can be studied, even long time experiments like neutron or light scattering are feasible since the bridge is in a steady-state equilibrium and can be kept stable for hours. It is also an electro-chemical reactor where compounds are transported through by the EHD flow, enabling the study of electrochemical reactions under potentials which are otherwise not easily accessible. Last but not least the bridge provides the experimental biologist with the opportunity to expose living organisms such as bacteria to electric fields without killing them, but with a significant influence on their behavior, and possibly, even on their genome.

  9. Williams syndrome

    Science.gov (United States)

    Williams-Beuren syndrome ... Williams syndrome is caused by not having a copy of several genes. It may be passed down in families. ... history of the condition. However, people with Williams syndrome have a 50% chance of passing the disorder ...

  10. Armstrong practices in Lunar Module simulator

    Science.gov (United States)

    1969-01-01

    Neil A. Armstrong, Commander for the Apollo 11 Moon-landing mission, practices for the historic event in a Lunar Module simulator in the Flight Crew Training building at KSC. Accompanying Armstrong on the Moon flight will be Command Module Pilot Michael Collins and Lunar Module Pilot Edwin E. Aldrin Jr.

  11. APOLLO 11 COMMANDER NEIL ARMSTRONG IN SIMULATOR

    Science.gov (United States)

    1969-01-01

    Apollo 11 commander Neil Armstrong is going through flight training in the lunar module simulator situated in the flight crew training building at KSC. Armstrong will pilot the lunar module to a moon landing on July 20, following launch from KSC on July 16.

  12. NASA Armstrong's Approach to Store Separation Analysis

    Science.gov (United States)

    Acuff, Chris; Bui, Trong

    2015-01-01

    Presentation will an overview of NASA Armstrong's store separation capabilities and how they have been applied recently. Objective of the presentation is to brief Generation Orbit and other potential partners on NASA Armstrong's store separation capabilities. It will include discussions on the use of NAVSEP and Cart3D, as well as some Python scripting work to perform the analysis, and a short overview of this methodology applied to the Towed Glider Air Launch System. Collaboration with potential customers in this area could lead to funding for the further development of a store separation capability at NASA Armstrong, which would boost the portfolio of engineering expertise at the center.

  13. Astronaut Neil Armstrong participates in simulation training

    Science.gov (United States)

    1969-01-01

    Astronaut Neil A. Armstrong, Apollo 11 commander, participates in simulation training in preparation for the scheduled lunar landing mission. He is in the Apollo Lunar Module Mission SImulator in the Kennedy Space Center's Flight Crew Training Building.

  14. Former Astronaut Neil A. Armstrong Visits MSFC

    Science.gov (United States)

    2007-01-01

    Among several other NASA dignitaries, former astronaut Neil A. Armstrong visited the Marshall Space Flight Center (MSFC) in attendance of the annual NASA Advisory Council Meeting. While here, Mr. Armstrong was gracious enough to allow the casting of his footprint. This casting will join those of other astronauts on display at the center. Armstrong was first assigned to astronaut status in 1962. He served as command pilot for the Gemini 8 mission, launched March 16, 1966, and performed the first successful docking of two vehicles in space. In 1969, Armstrong was commander of Apollo 11, the first manned lunar landing mission, and gained the distinction of being the first man to land a craft on the Moon and the first man to step on its surface. Armstrong subsequently held the position of Deputy Associate Administrator for Aeronautics, NASA Headquarters Office of Advanced Research and Technology, from 1970 to 1971. He resigned from NASA in 1971. Pictured with Armstrong is MSFC employee Daniel McFall, who assisted with the casting procedure.

  15. Official Portrait of Astronaut Neil Armstrong

    Science.gov (United States)

    1969-01-01

    Neil Armstrong, donned in his space suit, poses for his official Apollo 11 portrait. Armstrong began his flight career as a naval aviator. He flew 78 combat missions during the Korean War. Armstrong joined the NASA predecessor, NACA (National Advisory Committee for Aeronautics), as a research pilot at the Lewis Laboratory in Cleveland and later transferred to the NACA High Speed Flight Station at Edwards AFB, California. He was a project pilot on many pioneering high speed aircraft, including the 4,000 mph X-15. He has flown over 200 different models of aircraft, including jets, rockets, helicopters, and gliders. In 1962, Armstrong was transferred to astronaut status. He served as command pilot for the Gemini 8 mission, launched March 16, 1966, and performed the first successful docking of two vehicles in space. In 1969, Armstrong was commander of Apollo 11, the first manned lunar landing mission, and gained the distinction of being the first man to land a craft on the Moon and the first man to step on its surface. Armstrong subsequently held the position of Deputy Associate Administrator for Aeronautics, NASA Headquarters Office of Advanced Research and Technology, from 1970 to 1971. He resigned from NASA in 1971.

  16. David Owen WILLIAMS

    CERN Multimedia

    2006-01-01

    Lidy Williams-Oonk and her children Mark & Marietta, being unable to thank everybody individually, would like to express their sincere thanks to friends and colleagues at CERN and abroad for their great help and support, their messages and flowers, as well as their donations to the Ligue Genevoise contre le Cancer, on the death of their beloved husband and father.

  17. NASA Armstrong Flight Research Center Dynamics and Controls Branch

    Science.gov (United States)

    Jacobson, Steve

    2015-01-01

    NASA Armstrong continues its legacy of exciting work in the area of Dynamics and Control of advanced vehicle concepts. This presentation describes Armstrongs research in control of flexible structures, peak seeking control and adaptive control in the Spring of 2015.

  18. Astronaut Neil Armstrong participates in simulation of moon's surface

    Science.gov (United States)

    1969-01-01

    Astronaut Neil A. Armstrong, wearing an Extravehicular Mobility Unit, deploys a lunar surface television camera during lunar surface simulation training in bldg 9, Manned Spacecraft Center. Armstrong is the prime crew commander of the Apollo 11 lunar landing mission.

  19. Uncovering Heroes: A Conversation with Jennifer Armstrong.

    Science.gov (United States)

    Kerper, Richard M.

    2000-01-01

    Offers an interview with Jennifer Armstrong, writer of historical novels and nonfiction for children. Discusses her beginnings as a reader and a writer, her creative process, her purposes in writing nonfiction, her concerns about accuracy, and the origins of her second nonfiction book, "Shipwreck at the Bottom of the World: The Extraordinary…

  20. Former astronaut Armstrong witnesses STS-83 launch

    Science.gov (United States)

    1997-01-01

    Apollo l1 Commander Neil A. Armstrong and his wife, Carol, were among the many special NASA STS-83 launch guests who witnessed the liftoff of the Space Shuttle Columbia April 4 at the Banana Creek VIP Viewing Site at KSC. Columbia took off from Launch Pad 39A at 2:20:32 p.m. EST to begin the 16-day Microgravity Science Laboratory-1 (MSL-1) mission.

  1. Astronaut Neil Armstrong during thermovacuum training

    Science.gov (United States)

    1969-01-01

    Astronaut Neil A. Armstrong, commander of the Apollo 11 lunar landing mission, is photographed during thermovacuum training in Chamber B of the Space Environment Simulation Laboratory, Building 32, Manned Spacecraft Center. He is wearing an Extravehicular Mobility Unit. The training simulated lunar surface vacuum and thermal conditions during astronaut operations outside the Lunar Module on the moon's surface. The mirror was used to reflect solar light.

  2. 78 FR 28779 - Proposed Flood Elevation Determinations for Armstrong County, Pennsylvania (All Jurisdictions)

    Science.gov (United States)

    2013-05-16

    ... Armstrong County, Pennsylvania (All Jurisdictions) AGENCY: Federal Emergency Management Agency, DHS. ACTION... proposed rule concerning proposed flood elevation determinations for Armstrong County, Pennsylvania (All... sources in Armstrong County, Pennsylvania. Because FEMA has or [[Page 28780

  3. Astronaut Neil Armstrong participates in lunar surface siumlation training

    Science.gov (United States)

    1969-01-01

    Suited Astronaut Neil A. Armstrong, wearing an Extravehicular Mobility Unit, participates in lunar surface simulation training on April 18, 1969, in bldg 9, Manned Spacecraft Center (MSC). Armstrong is the prime crew commander of the Apollo 11 lunar landing mission. Here, he simulates scooping up a lunar surface sample.

  4. Astronaut Neil Armstrong participates in lunar surface simulation training

    Science.gov (United States)

    1969-01-01

    Astronaut Neil A. Armstrong, wearing an Extravehicular Mobility Unit (EMU), participates in lunar surface simulation training on April 18, 1969 in bldg 9, Manned Spacecraft Center. Armstrong is the prime crew commander of the Apollo 11 lunar landing mission. Here, he is standing on Lunar Module mockup foot pad preparing to ascend steps.

  5. Terve Maa uueks loomine / Mark Williams

    Index Scriptorium Estoniae

    Williams, Mark

    2010-01-01

    Rohelise liikumise asutaja Stewart Brandi hinnangutest kliimamuutustele, tuumaenergeetikale jt rohelise mõtteviisiga seotud mõistetele. S. Brandi arvates tuleb kriitiliselt hinnata vasakpoolsete roheliste arusaami ning aru saada, et ökoloogiliste muutuste puhul tuleb muuta ka kindlakskujunenud mõttestampe

  6. Characterization and Sintering of Armstrong Process Titanium Powder

    Science.gov (United States)

    Xu, Xiaoyan; Nash, Philip; Mangabhai, Damien

    2017-04-01

    Titanium and titanium alloys have a high strength to weight ratio and good corrosion resistance but also need longer time and have a higher cost on machining. Powder metallurgy offers a viable approach to produce near net-shape complex components with little or no machining. The Armstrong titanium powders are produced by direct reduction of TiCl4 vapor with liquid sodium, a process which has a relatively low cost. This paper presents a systematic research on powder characterization, mechanical properties, and sintering behavior and of Armstrong process powder metallurgy, and also discusses the sodium issue, and the advantages and disadvantages of Armstrong process powders.

  7. Astronauts Armstrong and Scott arrive at Hickam Field, Hawaii

    Science.gov (United States)

    1966-01-01

    Astronauts Neil A. Armstrong (center), command pilot, and David R. Scott, pilot, arrive at Hickam Field, Hawaii on their way from Naha, Okinawa, to Cape Kennedy, Florida. Astronaut Walter M. Schirra Jr. is at extreme left.

  8. Astronaut Neil A. Armstrong during water egress training

    Science.gov (United States)

    1965-01-01

    Astronaut Neil A. Armstrong, Gemini 5 backup crew command pilot, sits in the Gemini Static Article 5 spacecraft and prepares to be lowered from the deck of the NASA Motor Vessel Retriever for water egress training in the Gulf.

  9. Astronauts Armstrong and Scott during photo session outside KSC

    Science.gov (United States)

    1966-01-01

    Astronauts Neil A. Armstrong (left), command pilot, and David R. Scott, pilot, the Gemini 8 prime crew, during a photo session outside the Kennedy Space Center (KSC) Mission Control Center. They are standing in front of a radar dish.

  10. Astronaut Neil Armstrong studies rock samples during geological field trip

    Science.gov (United States)

    1969-01-01

    Astronaut Neil Armstrong, commander of the Apollo 11 lunar landing mission, studies rock samples during a geological field trip to the Quitman Mountains area near the Fort Quitman ruins in far west Texas.

  11. Apollo 11 astronaut Neil Armstrong suits up before launch

    Science.gov (United States)

    1969-01-01

    Apollo 11 Commander Neil Armstrong prepares to put on his helmet with the assistance of a spacesuit technician during suiting operations in the Manned Spacecraft Operations Building (MSOB) prior to the astronauts' departure to Launch Pad 39A. The three astronauts, Edwin E. Aldrin Jr., Neil A Armstrong and Michael Collins, will then board the Saturn V launch vehicle, scheduled for a 9:32 a.m. EDT liftoff, for the first manned lunar landing mission.

  12. Apollo 11 astronaut Neil Armstrong looks over flight plans

    Science.gov (United States)

    1969-01-01

    Apollo 11 Commander Neil Armstrong is looking over flight plans while being assisted by a spacesuit technician during suiting operations in the Manned Spacecraft Operations Building (MSOB) prior to the astronauts' departure to Launch Pad 39A. The three astronauts, Edwin E. Aldrin Jr., Neil A. Armstrong and Michael Collins will then board the Saturn V launch vehicle, scheduled for a 9:32 a.m. EDT liftoff, for the first manned lunar landing mission.

  13. Neil Armstrong chats with attendees at Apollo 11 anniversary banquet.

    Science.gov (United States)

    1999-01-01

    Former Apollo 11 astronaut Neil A. Armstrong is the center of attention at the anniversary banquet honoring the Apollo team, the people who made the entire lunar landing program possible. The banquet was held in the Apollo/Saturn V Center, part of the KSC Visitor Complex. This is the 30th anniversary of the Apollo 11 launch and moon landing, July 16 and July 20, 1969. Neil Armstrong was the first man to set foot on the moon. He appeared at the banquet with other former astronauts Edwin 'Buzz' Aldrin, Gene Cernan, Walt Cunningham and others.

  14. A Response to Armstrong and Read, Poirine and Bertram

    Directory of Open Access Journals (Sweden)

    Jerome L. McElroy

    2014-11-01

    Full Text Available This is a brief response to Armstrong and Read, Poirine, and Bertram, synthesizing their welcome thoughtful remarks in response to my paper, and briefly outlining the way forward that research in this area of island studies could take.

  15. Apollo 11 Astronaut Neil Armstrong Performs Ladder Practice

    Science.gov (United States)

    1969-01-01

    In preparation of the nation's first Lunar landing mission, Apollo 11 crew members underwent training activities to practice activities they would be performing during the mission. In this photograph, Neil Armstrong, donned in his space suit, practices getting back to the first rung of the ladder on the Lunar Module (LM). The Apollo 11 mission launched from the Kennedy Space Center (KSC) in Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. (Buzz) Aldrin Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  16. Armstrong Retrieves Equipment From Apollo 11 Storage Bay

    Science.gov (United States)

    1969-01-01

    The first manned lunar landing mission, Apollo 11, launched from the Kennedy Space Flight Center (KSC) in Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Astronauts onboard included Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin, Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon in the Sea of Tranquility. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew set up experiments, collected 47 pounds of lunar surface material for analysis back on Earth, planted the U.S Flag, and left a message for all mankind. In this photograph, Armstrong is removing scientific equipment from a storage bay of the LM. The brilliant sunlight emphasizes the U. S. Flag to the left. The object near the flag is the Solar Wind Composition Experiment deployed by Aldrin earlier.

  17. Reporters Interview Family of Apollo 11 Astronaut Neil Armstrong

    Science.gov (United States)

    1969-01-01

    Newsmen talked with the wife and sons of Apollo 11 astronaut Neil A. Armstrong after the successful launch of Apollo 11 on its trajectory to the moon. The Apollo 11 mission, the first lunar landing mission, launched from the Kennedy Space Center (KSC) in Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. (Buzz) Aldrin Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  18. Astronaut Aldrin is photographed by Astronaut Armstrong on the Moon

    Science.gov (United States)

    1969-01-01

    Apollo 11 Onboard Film -- The deployment of scientific experiments by Astronaut Edwin Aldrin Jr. is photographed by Astronaut Neil Armstrong. Man's first landing on the Moon occurred today at 4:17 p.m. as Lunar Module 'Eagle' touched down gently on the Sea of Tranquility on the east side of the Moon.

  19. Apollo 11 Astronaut Neil Armstrong Approaches Practice Helicopter

    Science.gov (United States)

    1969-01-01

    In preparation of the nation's first lunar landing mission, Apollo 11, crew members underwent training to practice activities they would be performing during the mission. In this photograph Neil Armstrong approaches the helicopter he flew to practice landing the Lunar Module (LM) on the Moon. The Apollo 11 mission launched from the Kennedy Space Center (KSC) in Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. (Buzz) Aldrin Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished

  20. Astronauts Scott and Armstrong undergoe water egress training

    Science.gov (United States)

    1966-01-01

    Astronauts Neil A. Armstrong (on left), command pilot, and David R. Scott, pilot of the Gemini 8 prime crew, use a boilerplate model of a Gemini spacecraft during water egress training in the Gulf of Mexico. Three Manned Spacecraft Center swimmers assist in the training exercise.

  1. Astronauts Armstrong and Aldrin study rock samples during field trip

    Science.gov (United States)

    1969-01-01

    Astronaut Neil Armstrong, commander of the Apollo 11 lunar landing mission, and Astronaut Edwin Aldrin, Lunar module pilot for Apollo 11, study rock samples during a geological field trip to the Quitman Mountains area near the Fort Quitman ruins in far west Texas.

  2. Apollo 11 Astronaut Neil Armstrong During Lunar Rock Collection Training

    Science.gov (United States)

    1969-01-01

    In this photograph, Apollo 11 astronaut Neil A. Armstrong uses a geologist's hammer in selecting rock specimens during a geological field trip to the Quitman Mountains area near the Fort Quitman ruins in far west Texas. Armstrong, alongside astronaut Edwin (Buzz) Aldrin, practiced gathering rock specimens using special lunar geological tools in preparation for the first Lunar landing. Mission was accomplished in July of the same year. Aboard the Marshall Space Fight center (MSFC) developed Saturn V launch vehicle, the Apollo 11 mission launched from The Kennedy Space Center, Florida on July 16, 1969 and safely returned to Earth on July 24, 1969. The 3-man crew aboard the flight consisted of Armstrong, commander; Aldrin, Lunar Module pilot; and a third astronaut Michael Collins, Command Module pilot. Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin, while Collins remained in lunar orbit. The crew collected 47 pounds of lunar surface material which was returned to Earth for analysis. The lunar surface exploration was concluded in 2½ hours.

  3. Lunar Landing Training vehicle piloted by Neil Armstrong during training

    Science.gov (United States)

    1969-01-01

    A Lunar Landing Training Vehicle, piloted by Astronaut Neil Armstrong, goes through a checkout flight at Ellington Air Force Base on June 16, 1969. The total duration of the lunar simulation flight was five minutes and 59 seconds. Maximum altitude attained was about 300 feet.

  4. Pursuing the Panderer: An Analysis of "United States v. Williams"

    Science.gov (United States)

    McGrain, Patrick N.; Moore, Jennifer L.

    2010-01-01

    In May 2008, the Supreme Court addressed whether the government can regulate the ownership and distribution of virtual child pornography. "U.S. v. Williams" marked the first time the Court directly addressed the concept of pandering virtual child pornography. This article examines the Court's decision in "U.S. v. Williams" and…

  5. Apollo 11 Commander Armstrong Presents President With Commemorative Plaque

    Science.gov (United States)

    1974-01-01

    On June 4, 1974, 5 years after the successful Apollo 11 lunar landing mission, commander Neil Armstrong (right) presented a plaque to U.S. President Richard Milhous Nixon (left) on behalf of all people who had taken part in the space program. In making the presentation, Armstrong said 'Mr. President, you have proclaimed this week to be United States Space week in conjunction with the fifth anniversary of our first successful landing on the Moon. It is my privilege to represent my colleagues, the crewmen of projects Mercury, Gemini, Apollo, and Skylab, and the men and women of NASA, and the hundreds of thousands of Americans from across the land who contributed so mightily to the success of our efforts in space in presenting this plaque which bears the names of each individual who has had the privilege of representing this country' in a space flight. The presentation was made at the California white house in San Clemente.

  6. Armstrong Flight Research Center Research Technology and Engineering 2017

    Science.gov (United States)

    Voracek, David F. (Editor)

    2018-01-01

    I am delighted to present this report of accomplishments at NASA's Armstrong Flight Research Center. Our dedicated innovators possess a wealth of performance, safety, and technical capabilities spanning a wide variety of research areas involving aircraft, electronic sensors, instrumentation, environmental and earth science, celestial observations, and much more. They not only perform tasks necessary to safely and successfully accomplish Armstrong's flight research and test missions but also support NASA missions across the entire Agency. Armstrong's project teams have successfully accomplished many of the nation's most complex flight research projects by crafting creative solutions that advance emerging technologies from concept development and experimental formulation to final testing. We are developing and refining technologies for ultra-efficient aircraft, electric propulsion vehicles, a low boom flight demonstrator, air launch systems, and experimental x-planes, to name a few. Additionally, with our unique location and airborne research laboratories, we are testing and validating new research concepts. Summaries of each project highlighting key results and benefits of the effort are provided in the following pages. Technology areas for the projects include electric propulsion, vehicle efficiency, supersonics, space and hypersonics, autonomous systems, flight and ground experimental test technologies, and much more. Additional technical information is available in the appendix, as well as contact information for the Principal Investigator of each project. I am proud of the work we do here at Armstrong and am pleased to share these details with you. We welcome opportunities for partnership and collaboration, so please contact us to learn more about these cutting-edge innovations and how they might align with your needs.

  7. Apollo 11 Cmdr Neil Armstrong watches STS-83 launch

    Science.gov (United States)

    1997-01-01

    Apollo 11 Commander Neil A. Armstrong and his wife, Carol, were among the many special NASA STS-83 launch guests who witnessed the liftoff of the Space Shuttle Columbia April 4 at the Banana Creek VIP Viewing Site at KSC. Columbia took off from Launch Pad 39A at 2:20:32 p.m. EST to begin the 16-day Microgravity Science Laboratory-1 (MSL-1) mission.

  8. Astronaut Neil A. Armstrong Undergoes Communications Systems Final Check

    Science.gov (United States)

    1969-01-01

    Dunned in his space suit, mission commander Neil A. Armstrong does a final check of his communications system before before the boarding of the Apollo 11 mission. Launched via a Saturn V launch vehicle, the first manned lunar mission launched from the Kennedy Space Center, Florida on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. The 3-man crew aboard the flight consisted of astronauts Armstrong; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin, Jr., Lunar Module (LM) Pilot. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. Meanwhile, astronaut Collins piloted the CM in a parking orbit around the Moon. During a 2½ hour surface exploration, the crew collected 47 pounds of lunar surface material which was returned to Earth for analysis. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  9. Armstrong Flight Research Center Research Technology and Engineering Report 2015

    Science.gov (United States)

    Voracek, David F.

    2016-01-01

    I am honored to endorse the 2015 Neil A. Armstrong Flight Research Center’s Research, Technology, and Engineering Report. The talented researchers, engineers, and scientists at Armstrong are continuing a long, rich legacy of creating innovative approaches to solving some of the difficult problems and challenges facing NASA and the aerospace community.Projects at NASA Armstrong advance technologies that will improve aerodynamic efficiency, increase fuel economy, reduce emissions and aircraft noise, and enable the integration of unmanned aircraft into the national airspace. The work represented in this report highlights the Center’s agility to develop technologies supporting each of NASA’s core missions and, more importantly, technologies that are preparing us for the future of aviation and space exploration.We are excited about our role in NASA’s mission to develop transformative aviation capabilities and open new markets for industry. One of our key strengths is the ability to rapidly move emerging techniques and technologies into flight evaluation so that we can quickly identify their strengths, shortcomings, and potential applications.This report presents a brief summary of the technology work of the Center. It also contains contact information for the associated technologists responsible for the work. Don’t hesitate to contact them for more information or for collaboration ideas.

  10. Armstrong City: A Permanent Settlement for Exo-Planetary Studies

    Science.gov (United States)

    Greenspon, J.

    Development of a permanent placement lunar base is the next fundamental step in an international program to explore and settle other planets within our solar system. While technical, operational, managerial and long-term issues must be considered, the establishment of a lunar facility can serve the preliminary needs of manned civilization in space. Numerous issues become apparent in the consideration of the activation of a lunar base. Specific and realistic determinations must be made about various types of interests in addition to the general conjectures given above. These activities include: - Spacecraft landings and vehicle systems - Crew selection, supplies and habitability - Power production and distribution - Risk management - Science and lunar activities - Base planning and configurations - Integrated operations and maintenance - Management. The development and activation of a lunar colony will require careful consideration to the future of space activities and operations in near Earth space. A lunar city, which we call Armstrong city, is defined by its own unique natural environment, available technology, realistic objectives, and common sense. Armstrong City, a preliminary first lunar base, will most probably be serving as an extended "division" of Earth's space exploration offices. The reasons are very simple and practical. -First, the costs of maintaining a permanent space facility will be lower in the long run than the costs of a series of short duration, rotating manned bases, -Second, studies in long-term space habitation can effectively be carried out in relative safety, -Third, the initial tasks which need to be done will define and establish methodologies and issues for development of future extraterrestrial base concepts, and -Fourth, the complexities of the initial facilities necessary to sustain the citizens can be tempered through developing local resources and reproducible research. In order to bring about development of Armstrong City, four

  11. Former Dryden pilot and NASA astronaut Neil Armstrong

    Science.gov (United States)

    1991-01-01

    Famed astronaut Neil A. Armstrong, the first man to set foot on the moon during the historic Apollo 11 space mission in July 1969, served for seven years as a research pilot at the NACA-NASA High-Speed Flight Station, now the Dryden Flight Research Center, at Edwards, California, before he entered the space program. Armstrong joined the National Advisory Committee for Aeronautics (NACA) at the Lewis Flight Propulsion Laboratory (later NASA's Lewis Research Center, Cleveland, Ohio, and today the Glenn Research Center) in 1955. Later that year, he transferred to the High-Speed Flight Station at Edwards as an aeronautical research scientist and then as a pilot, a position he held until becoming an astronaut in 1962. He was one of nine NASA astronauts in the second class to be chosen. As a research pilot Armstrong served as project pilot on the F-100A and F-100C aircraft, F-101, and the F-104A. He also flew the X-1B, X-5, F-105, F-106, B-47, KC-135, and Paresev. He left Dryden with a total of over 2450 flying hours. He was a member of the USAF-NASA Dyna-Soar Pilot Consultant Group before the Dyna-Soar project was cancelled, and studied X-20 Dyna-Soar approaches and abort maneuvers through use of the F-102A and F5D jet aircraft. Armstrong was actively engaged in both piloting and engineering aspects of the X-15 program from its inception. He completed the first flight in the aircraft equipped with a new flow-direction sensor (ball nose) and the initial flight in an X-15 equipped with a self-adaptive flight control system. He worked closely with designers and engineers in development of the adaptive system, and made seven flights in the rocket plane from December 1960 until July 1962. During those fights he reached a peak altitude of 207,500 feet in the X-15-3, and a speed of 3,989 mph (Mach 5.74) in the X-15-1. Armstrong has a total of 8 days and 14 hours in space, including 2 hours and 48 minutes walking on the Moon. In March 1966 he was commander of the Gemini 8

  12. Telecast of Astronauts Armstrong and Aldrin by the Lunar Module

    Science.gov (United States)

    1969-01-01

    Astronauts Neil A. Armstrong (in center) commander; and Edwin E. Aldrin Jr. (on right), lunar module pilot, are seen standing near their Lunar Module in this black and white reproduction taken from a telecast by the Apollo 11 lunar surface television camera during the Apollo 11 extravehicular activity. This picture was made from a televised image received at the Deep Space Network tracking station at Goldstone, California. President Richard M. Nixon had just spoken to the two astronauts by radio and Aldrin, a colonel in the U.S. Air Force, is saluting the president.

  13. Neural Correlates of Amusia in Williams Syndrome

    OpenAIRE

    Lense, Miriam D.; Dankner, Nathan; Pryweller, Jennifer R.; Thornton-Wells, Tricia A.; Dykens, Elisabeth M.

    2014-01-01

    Congenital amusia is defined by marked deficits in pitch perception and production. Though historically examined only in otherwise typically developing (TD) populations, amusia has recently been documented in Williams syndrome (WS), a genetic, neurodevelopmental disorder with a unique auditory phenotype including auditory sensitivities and increased emotional responsiveness to music but variable musical skill. The current study used structural T1-weighted magnetic resonance imaging and diffus...

  14. Multi-modal virtual environment research at Armstrong Laboratory

    Science.gov (United States)

    Eggleston, Robert G.

    1995-01-01

    One mission of the Paul M. Fitts Human Engineering Division of Armstrong Laboratory is to improve the user interface for complex systems through user-centered exploratory development and research activities. In support of this goal, many current projects attempt to advance and exploit user-interface concepts made possible by virtual reality (VR) technologies. Virtual environments may be used as a general purpose interface medium, an alternative display/control method, a data visualization and analysis tool, or a graphically based performance assessment tool. An overview is given of research projects within the division on prototype interface hardware/software development, integrated interface concept development, interface design and evaluation tool development, and user and mission performance evaluation tool development.

  15. Genetics Home Reference: Williams syndrome

    Science.gov (United States)

    ... do well on tasks that involve spoken language, music, and learning by repetition (rote memorization). Affected individuals ... Resources (5 links) Disease InfoSearch: Williams syndrome Genetic Science Learning Center, University of Utah MalaCards: williams-beuren ...

  16. William Wilde: Historian.

    Science.gov (United States)

    Geary, L

    2016-05-01

    This essay attempts to assess William Wilde as a social historian. It examines some of his contributions to the discipline of history and looks particularly at 'The food of the Irish', which was published in the Dublin University Magazine in February 1854.

  17. Anderson, Prof. Basil Williams

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1964 Honorary. Anderson, Prof. Basil Williams. Date of birth: 3 July 1901. Date of death: 24 February 1984. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held ...

  18. Florence Jessie Mac Williams

    Indian Academy of Sciences (India)

    CPMGIKAlBGE-340/2003-05. Resonance - January 2005. Licenced to post WPP No.6 RT Nagar Postoffice. Florence Jessie Mac Williams. (1917 - 1990). Registered with Registrar of Newspapers in India vide Regn. No. 66273/96. ISSN 0971-8044. Price per copy: Rs 40.

  19. Interaction with William Carnall

    International Nuclear Information System (INIS)

    Judd, Brian R.

    2005-01-01

    A personal account is given of interaction with William T. Carnall during the period 1977-1988, when I made regular visits to the Argonne National Laboratory to discuss the theoretical background to the spectroscopic work he was carrying out on the lanthanides and actinides

  20. Series, Prof. George William

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1984 Honorary. Series, Prof. George William. Date of birth: 22 February 1920. Date of death: 2 January 1995. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held ...

  1. Portrait of Astronaut Neil A. Armstrong, commander of Apollo 11 mission

    Science.gov (United States)

    1969-01-01

    Portrait of Astronaut Neil A. Armstrong, commander of the Apollo 11 Lunar Landing mission in his space suit, with his helmet on the table in front of him. Behind him is a large photograph of the lunar surface.

  2. Astronaut Neil Armstrong in Launch Complex 16 trailer during suiting up

    Science.gov (United States)

    1966-01-01

    Astronaut Neil A. Armstrong, command pilot of the Gemini 8 space flight, sits in the Launch Complex 16 trailer during suiting up operations for the Gemini 8 mission. Suit technician Jim Garrepy assists.

  3. Williams propylene upgrading

    Energy Technology Data Exchange (ETDEWEB)

    Chappell, D. [Williams Energy Canada Inc., Edmonton, AB (Canada)

    2004-07-01

    Edmonton-based Williams Energy Canada Inc. extracts petrochemicals from oil sands and operates a straddle plant business and an olefins business. This presentation provided an update of both businesses and reviewed the advantage of polypropylene production in Alberta, with reference to premium markets and to comparative rail costs to Chicago via Texas, and rail costs to Chicago from Alberta. Williams' straddle plant business includes the Cochrane Straddle Plant, the Empress 2 Straddle Plant, and the Empress 5 Straddle Plant. The Fort McMurray Extraction Plant was also described along with the Redwater Olefins Fractionator and its potential for salt cavern storage and distribution. It was noted that Alberta is well positioned for polypropylene production because it already has a secure supply and an excellent distribution network. tabs., figs.

  4. Williams propylene upgrading

    International Nuclear Information System (INIS)

    Chappell, D.

    2004-01-01

    Edmonton-based Williams Energy Canada Inc. extracts petrochemicals from oil sands and operates a straddle plant business and an olefins business. This presentation provided an update of both businesses and reviewed the advantage of polypropylene production in Alberta, with reference to premium markets and to comparative rail costs to Chicago via Texas, and rail costs to Chicago from Alberta. Williams' straddle plant business includes the Cochrane Straddle Plant, the Empress 2 Straddle Plant, and the Empress 5 Straddle Plant. The Fort McMurray Extraction Plant was also described along with the Redwater Olefins Fractionator and its potential for salt cavern storage and distribution. It was noted that Alberta is well positioned for polypropylene production because it already has a secure supply and an excellent distribution network. tabs., figs

  5. Artists concept of Apollo 11 Astronaut Neil Armstrong on the moon

    Science.gov (United States)

    1969-01-01

    A Grumman Aircraft Engineering Corporation artist's concept depicting mankind's first walk on another celestianl body. Here, Astronaut Neil Armstrong, Apollo 11 commander, is making his first step onto the surface of the moon. In the background is the Earth, some 240,000 miles away. Armstrong. They are continuing their postflight debriefings. The three astronauts will be released from quarantine on August 11, 1969. Donald K. Slayton (right), MSC Director of Flight Crew Operations; and Lloyd Reeder, training coordinator.

  6. Cold Spraying of Armstrong Process Titanium Powder for Additive Manufacturing

    Science.gov (United States)

    MacDonald, D.; Fernández, R.; Delloro, F.; Jodoin, B.

    2017-04-01

    Titanium parts are ideally suited for aerospace applications due to their unique combination of high specific strength and excellent corrosion resistance. However, titanium as bulk material is expensive and challenging/costly to machine. Production of complex titanium parts through additive manufacturing looks promising, but there are still many barriers to overcome before reaching mainstream commercialization. The cold gas dynamic spraying process offers the potential for additive manufacturing of large titanium parts due to its reduced reactive environment, its simplicity to operate, and the high deposition rates it offers. A few challenges are to be addressed before the additive manufacturing potential of titanium by cold gas dynamic spraying can be reached. In particular, it is known that titanium is easy to deposit by cold gas dynamic spraying, but the deposits produced are usually porous when nitrogen is used as the carrier gas. In this work, a method to manufacture low-porosity titanium components at high deposition efficiencies is revealed. The components are produced by combining low-pressure cold spray using nitrogen as the carrier gas with low-cost titanium powder produced using the Armstrong process. The microstructure and mechanical properties of additive manufactured titanium components are investigated.

  7. Repetition Priming in Adults with Williams Syndrome: Age-Related Dissociation between Implicit and Explicit Memory

    Science.gov (United States)

    Krinsky-McHale, Sharon J.; Kittler, Phyllis; Brown, W. Ted; Jenkins, Edmund C.; Devenny, Darlynne A.

    2005-01-01

    We examined implicit and explicit memory in adults with Williams syndrome. An age-related dissociation was found; repetition priming (reflecting implicit memory) did not show change with age, but free recall (reflecting explicit memory) was markedly reduced. We also compared the performance of adults with Williams syndrome to adults with Down…

  8. Raymond Williams and local cultures

    OpenAIRE

    B Longhurst

    1991-01-01

    In this paper it is maintained that Raymond Williams's writings on culture are of great importance to current developments in cultural geography. His work is periodised into three stages and its different subject matters identified. An interpretation of Williams's theory of culture is offered which places particular emphasis on his concepts of 'structure of feeling' and 'knowable community'. The creative tension between Williams's holistic treatment of culture and his stress on cultural strug...

  9. Whither Sir William?

    Directory of Open Access Journals (Sweden)

    Stephen J. Greenberg, MSLS, PhD

    2017-04-01

    Full Text Available There are times when something is simply so familiar that we can no longer see it at all. It can be a story, or a concept, or even a flesh-and-blood person. Familiarity breeds not only contempt, but a kind of invisibility as well. For too many of us, such is the case with Sir William Osler. In his time (1849–1919, many considered him to be one of the greatest practitioners, teachers, and writers ever in the field of medicine. He was instrumental in the founding of the Medical Library Association (MLA and was elected its second president.

  10. Stretch Marks

    Science.gov (United States)

    ... completely without the help of a dermatologist or plastic surgeon. These doctors may use one of many types of treatments — from actual surgery to techniques like microdermabrasion and laser treatment — to reduce the appearance of stretch marks. These techniques are ...

  11. 'The chearful haunts': John Armstrong (1709-1779), physician, poet, satirist and leveller of medical knowledge.

    Science.gov (United States)

    Bryan, Charles S; Scott, Patrick

    2015-11-01

    John Armstrong, the first honours graduate of the University of Edinburgh School of Medicine, was famous in his day for a lengthy didactic poem entitled The Art of Preserving Health (1744). He is now obscure except to scholars specializing in the 18th century and, when discussed at all, often dismissed as a failed physician who wrote mediocre poetry in a quest for money and fame. A new exegesis by Adam Budd exhumes Armstrong as an original voice who offered timely and reassuring advice to Britons as they braced for another epidemic of plague; who depicted illness through the lens of a vulnerable and sympathetic physician, and who was perhaps above all else a leveller of medical knowledge. Elaborating on Budd's thesis, it would seem that Armstrong, a complicated man, has frequently been misread and was in some ways ahead of his time. © The Author(s) 2014.

  12. Negotiating Primitivist Modernisms: Louis Armstrong, Robert Goffin, and the Transatlantic Jazz Debate

    Directory of Open Access Journals (Sweden)

    Daniel Stein

    2011-10-01

    Full Text Available “Dear Pal Goffin,” Louis Armstrong wrote to his Belgian acquaintance, the lawyer, hobby journalist, and jazz historian Robert Goffin, on July 19, 1944. “‘Man—I’ve been trying to get in touch with you […]. Here’s another hundred dollars toward the five hundred. […] So accept this hundred and I’ll send the other before a ‘Black Cat can ‘Lick his ‘Bu‘hind’ ….. haw haw haw…” (80. Sending Goffin a batch of money along with this playfully worded missive, Armstrong was hoping for quick results. He ...

  13. Neil Armstrong gets round of applaus at Apollo 11 anniversary banquet.

    Science.gov (United States)

    1999-01-01

    Former Apollo 11 astronaut Neil A. Armstrong stands to a round of applause after being introduced at the anniversary banquet honoring the Apollo team, the people who made the entire lunar landing program possible. The banquet was held in the Apollo/Saturn V Center, part of the KSC Visitor Complex. This is the 30th anniversary of the Apollo 11 launch and moon landing, July 16 and July 20, 1969. Neil Armstrong was the first man to set foot on the moon. He appeared at the banquet with other former astronauts Edwin 'Buzz' Aldrin, Gene Cernan, Walt Cunningham and others.

  14. Test pilots 1962 - Armstrong, Walker, Dana, Peterson, McKay, Thompson, Butchart

    Science.gov (United States)

    1962-01-01

    The research pilots at what in 1962 was called the Flight Research Center standing in front of the X-1E. They are (left to right) Neil Armstrong, Joe Walker, Bill Dana, Bruce Peterson, Jack McKay, Milt Thompson, and Stan Butchart. of the group, Armstrong, Walker, Dana, McKay and Thompson all flew the X-15. Bruce Peterson flew the M2-F2 and HL-10 lifting bodies, while Stan Butchart was the B-29 drop plane pilot for many of the D-558-II and X-1 series research aircraft.

  15. The Connection of Samuel Chapman Armstrong as both Borrower and Architect of Education in Hawai'i

    Science.gov (United States)

    Beyer, C. Kalani

    2007-01-01

    Samuel Chapman Armstrong is well known for establishing Hampton Institute, the institution most involved with training black teachers in the South after the Civil War. It is less known that he was born in Hawai'i to the missionary couple Reverend Richard and Clarissa Chapman Armstrong. His parents were members of the Fifth Company of missionaries…

  16. Coronary ostium occlusion by coronary cusp displacement in Williams syndrome.

    Science.gov (United States)

    Shiohama, Tadashi; Fujii, Katsunori; Ebata, Ryota; Funabashi, Nobusada; Matsumiya, Goro; Saito, Yuko Kazato; Takechi, Fumie; Yonemori, Yoko; Nakatani, Yukio; Shimojo, Naoki

    2016-06-01

    Williams syndrome is a contiguous gene deletion syndrome resulting from a heterozygous deletion on chromosome 7q11.23, and is characterized by distinctive facial features and supravalvular aortic stenosis (SVAS). This syndrome rarely presents unpredictable cardiac death, and yet, as illustrated in the present case, it is still not possible to predict it, even on close monitoring. We herein describe the case of a 6-year-old Japanese girl with Williams syndrome, who had sudden cardiac collapse due to cardiac infarction after pharyngitis. Cardiac failure followed a critical course that did not respond to catecholamine support or heart rest with extracardiac mechanical support. Although marked coronary stenosis was not present, the left coronary cusp abnormally adhered to the aortic wall, which may synergistically cause coronary ostium occlusion with SVAS. Altered hemodynamic state, even that caused by the common cold, may lead to critical myocardial events in Williams syndrome with SVAS. © 2015 Japan Pediatric Society.

  17. [William Harvey revisited ].

    Science.gov (United States)

    Steinke, Hubert

    2015-07-01

    William Harvey's discovery of the circulation of the blood is often described as a product of the Scientific Revolution of the Seventeenth Century. Modern research has, however, shown thatHarvey followed the Aristotelian research tradition and thus tried to reveal the purpose of the organs through examination of various animals. His publication of 1628 has to be read as an argument of natural philosophy, or, more precisely, as a series of linked observations, experiments and philosophical reasonings from which the existence of circulation has to be deduced as a logical consequence. Harvey did not consider experiments as superior to philosophical reasoning nor intended he to create a new system of medicine. He believed in the vitality of the heart and the blood and rejected Francis Bacon's empirism and the mechanistic rationalism of Descartes. Harvey's contribution and originality lied less in his single observations and experiments but in the manner how he linked them with critical reasoning and how he accepted, presented and defended the ensuing radical findings.

  18. William Rowan Hamilton: Mathematical genius

    Energy Technology Data Exchange (ETDEWEB)

    Wilkins, D.R. [School of Mathematics, Trinity College, Dublin (Ireland)]. E-mail: dwilkins@maths.tcd.ie

    2005-08-01

    This year Ireland celebrates the bicentenary of the mathematician William Rowan Hamilton, best remembered for 'quaternions' and for his pioneering work on optics and dynamics. Two centuries after his birth, the extent to which terms such as 'Hamiltonian' and 'Hamiltonian system' have entered the everyday language of mathematicians and physicists testifies to the continuing impact of the scientific work of William Rowan Hamilton. (U.K.)

  19. William Rowan Hamilton: Mathematical genius

    International Nuclear Information System (INIS)

    Wilkins, D.R.

    2006-01-01

    This year Ireland celebrates the bicentenary of the mathematician William Rowan Hamilton, best remembered for quaternions and for his pioneering work on optics and dynamics. Two centuries after his birth, the extent to which terms such as Hamiltonian and Hamiltonian system have entered the everyday language of mathematicians and physicists testifies to the continuing impact of the scientific work of William Rowan Hamilton. (U.K.)

  20. Prayer marks.

    Science.gov (United States)

    Abanmi, Abdullah A; Al Zouman, Abdulrahman Y; Al Hussaini, Husa; Al-Asmari, Abdulrahman

    2002-07-01

    Prayer marks (PMs) are asymptomatic, chronic skin changes that consist mainly of thickening, lichenification, and hyperpigmentation, and develop over a long period of time as a consequence of repeated, extended pressure on bony prominences during prayer. Three hundred and forty-nine Muslims and 24 non-Muslims were examined for the appearance of PMs at different body sites. The prospective study of 349 Muslims (both males and females) with regular praying habits showed the occurrence of PMs on specific locations, such as the forehead, knees, ankles, and dorsa of the feet, leading to dermatologic changes consisting of lichenification and hyperpigmentation. The incidence of PMs was significantly higher in males than in females. Older subjects (over 50 years of age) demonstrated a significantly higher frequency of lichenification and hyperpigmentation, suggesting that repeated pressure and friction for prolonged periods are the causative factors for the development of PMs. Histologic examination of skin biopsies from the affected sites showed compact orthokeratosis, hypergranulosis, dermal papillary fibrosis, and dermal vascularization. PMs were not associated with any risk of secondary complications, such as erythema, bullous formation, and infections. PMs are commonly occurring dermatologic changes in Muslims who pray for prolonged periods.

  1. 33 CFR 167.1702 - In Prince William Sound: Prince William Sound Traffic Separation Scheme.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false In Prince William Sound: Prince William Sound Traffic Separation Scheme. 167.1702 Section 167.1702 Navigation and Navigable Waters COAST....1702 In Prince William Sound: Prince William Sound Traffic Separation Scheme. The Prince William Sound...

  2. The Heuristic Method, Precursor of Guided Inquiry: Henry Armstrong and British Girls' Schools, 1890-1920

    Science.gov (United States)

    Rayner-Canham, Geoff; Rayner-Canham, Marelene

    2015-01-01

    Though guided-inquiry learning, discovery learning, student-centered learning, and problem-based learning are commonly believed to be recent new approaches to the teaching of chemistry, in fact, the concept dates back to the late 19th century. Here, we will show that it was the British chemist, Henry Armstrong, who pioneered this technique,…

  3. Winning the Race: Lance Armstrong Shares His Struggle To Survive Cancer... and Thrive!

    Science.gov (United States)

    ... to send to people recently diagnosed with cancer? Hope. There can and should be life after cancer for more people, and I want ... does the future hold for Lance Armstrong? I hope to live up to the words ... opportunity to live their life on their own terms. I am grateful for ...

  4. Apollo 11 Astronaut Armstrong Arrives at the Flight Crew Training Building

    Science.gov (United States)

    1969-01-01

    In this photograph, Apollo 11 astronaut Neil Armstrong walks to the flight crew training building at the NASA Kennedy Space Center (KSC) in Florida, one week before the nation's first lunar landing mission. The Apollo 11 mission launched from KSC via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. (Buzz) Aldrin Jr., Lunar Module (LM) pilot. The CM, 'Columbia', piloted by Collins, remained in a parking orbit around the Moon while the LM, 'Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  5. A Portrait of the Jester as Observer: An Interview with Dr. Thomas Armstrong.

    Science.gov (United States)

    Prystowsky, Richard J.; Miles, Charlie

    2000-01-01

    Educator and author Tom Armstrong talks about events that influenced his radical educational philosophy; the interconnectedness of spirituality, culture, and the inner learner in all of us; the difficulty of linking spirituality to education in light of the First Amendment; attention deficit disorders and the medicalization of education; and the…

  6. [Williams-Beuren syndrome (Williams syndrome). Case report].

    Science.gov (United States)

    Miklós, Györgyi; Fekete, György; Haltrich, Irén; Tóth, Miklós; Reismann, Péter

    2017-11-01

    Williams syndrome is a rare genetic disorder, that occurs equally in all ethnic groups and both sexes. The diagnosis might be missed during childhood in mild cases. However, establishing the diagnosis is important, not only to find the cause of intellectual disability but to look for cardiovascular, endocrine, psychiatry, urology and other conditions, which can occur at any age in the patients' lifetime. This case report presents the story of 47-year-old woman, who was admitted with haematemesis. During her stay on the ward, in the light of the distinctive facial features, mental retardation, and social behaviour patterns, the possibility of Williams syndrome emerged. Later, the diagnosis was confirmed by genetic analysis. This female is the oldest living patient with Williams syndrome in Hungary. Orv Hetil. 2017; 158(47): 1883-1888.

  7. NASA Administrator Dan Goldin greets Neil Armstrong at Apollo 11 anniversary banquet.

    Science.gov (United States)

    1999-01-01

    During an anniversary banquet honoring the Apollo team, the people who made the entire lunar landing program possible, former Apollo astronaut Neil A. Armstrong (left) shakes the hand of Judy Goldin (center), wife of NASA Administrator Daniel S. Goldin (right). The banquet was held in the Apollo/Saturn V Center, part of the KSC Visitor Complex. This is the 30th anniversary of the Apollo 11 launch and moon landing, July 16 and July 20, 1969. Among the guests at the banquet were former Apollo astronauts are Neil A. Armstrong and Edwin 'Buzz' Aldrin who flew on Apollo 11, the launch of the first moon landing; Gene Cernan, who flew on Apollo 10 and 17 and was the last man to walk on the moon; and Walt Cunningham, who flew on Apollo 7.

  8. Artist's rendering of astronaut Neil Armstrong planting U.S. flag on Moon

    Science.gov (United States)

    1969-01-01

    Artist's Concept: Apollo 11 astronaut Neil Armstrong, after stepping onto the lunar surface, will plant the United States flag in its soil. The flag will be made of nylone, size 3- by 5 feet on a staff 8 feet long. During flight it will be stowed in two 4-foot sections strapped to the Lunar Module ladder. Armstrong's first assignment after stepping off the ladder is to pull a 'D' ring to start a television camera. The second assignment is to erect the U.S. flag. The flag will appear to be flying in a breeze. This is done with a spring-loaded wire in the nylon cloth. With everything is working normally, this will be observed on live television.

  9. Telecast of Astronaut Neil Armstrong descending ladder to surface of the moon

    Science.gov (United States)

    1969-01-01

    Astronaut Neil A. Armstrong, Apollo 11 commander, descends the ladder of the Apollo 11 Lunar Module prior to making the first step by man on the moon. This view is a black and white reproduction taken from a telecast by the Apollo 11 lunar surface camera during extravehicular activity. The black bar running through the center of the picture is an anamoly in the television ground data system at the Goldstone Tracking Station.

  10. Telecast of Astronauts Armstrong and Aldrin by the Lunar Module ladder

    Science.gov (United States)

    1969-01-01

    Astronauts Neil A. Armstrong (on left), commander; and Edwin E. Aldrin Jr., lunar module pilot, are seen standing by the Lunar Module ladder in this black and white reproduction taken from a telecast by the Apollo 11 lunar surface television camera during the Apollo 11 extravehicular activity. This picture was made from a televised image received at the Deep Space Network tracking station at Goldstone, California.

  11. Interview: William and Barbara Christopher.

    Science.gov (United States)

    Teaching Exceptional Children, 1986

    1986-01-01

    Asserting that the biggest mistake educators can make is to set themselves up as experts vis-a-vis parents as amateurs, Barbara and William Christopher emphasize the importance of continued education for the autistic individual and relate their experiences with the educational community as they sought help for their autistic son. (JC)

  12. Cyclic loading of thick vessels based on the Prager and Armstrong-Frederick kinematic hardening models

    International Nuclear Information System (INIS)

    Mahbadi, H.; Eslami, M.R.

    2006-01-01

    The aim of this paper is to relate the type of stress category in cyclic loading to ratcheting or shakedown behaviour of the structure. The kinematic hardening theory of plasticity based on the Prager and Armstrong-Frederick models is used to evaluate the cyclic loading behaviour of thick spherical and cylindrical vessels under load and deformation controlled stresses. It is concluded that kinematic hardening based on the Prager model under load and deformation controlled conditions, excluding creep, results in shakedown or reversed plasticity for spherical and cylindrical vessels with the isotropy assumption of the tension/compression curve. Under an anisotropy assumption of the tension/compression curve, this model predicts ratcheting. On the other hand, the Armstrong-Frederick model predicts ratcheting under load controlled cyclic loading and reversed plasticity for deformation controlled stress. The interesting conclusion is that the Armstrong-Frederick model is well capable to predict the experimental data under the assumed type of stresses, wherever experimental data are available

  13. Former Dryden pilot and NASA astronaut Neil Armstrong being inducted into the Aerospace Walk of Hono

    Science.gov (United States)

    1991-01-01

    Famed astronaut Neil A. Armstrong, the first man to set foot on the moon during the historic Apollo 11 space mission in July 1969, served for seven years as a research pilot at the NACA-NASA High-Speed Flight Station, now the Dryden Flight Research Center, at Edwards, California, before he entered the space program. Armstrong joined the National Advisory Committee for Aeronautics (NACA) at the Lewis Flight Propulsion Laboratory (later NASA's Lewis Research Center, Cleveland, Ohio, and today the Glenn Research Center) in 1955. Later that year, he transferred to the High-Speed Flight Station at Edwards as an aeronautical research scientist and then as a pilot, a position he held until becoming an astronaut in 1962. He was one of nine NASA astronauts in the second class to be chosen. As a research pilot Armstrong served as project pilot on the F-100A and F-100C aircraft, F-101, and the F-104A. He also flew the X-1B, X-5, F-105, F-106, B-47, KC-135, and Paresev. He left Dryden with a total of over 2450 flying hours. He was a member of the USAF-NASA Dyna-Soar Pilot Consultant Group before the Dyna-Soar project was cancelled, and studied X-20 Dyna-Soar approaches and abort maneuvers through use of the F-102A and F5D jet aircraft. Armstrong was actively engaged in both piloting and engineering aspects of the X-15 program from its inception. He completed the first flight in the aircraft equipped with a new flow-direction sensor (ball nose) and the initial flight in an X-15 equipped with a self-adaptive flight control system. He worked closely with designers and engineers in development of the adaptive system, and made seven flights in the rocket plane from December 1960 until July 1962. During those fights he reached a peak altitude of 207,500 feet in the X-15-3, and a speed of 3,989 mph (Mach 5.74) in the X-15-1. Armstrong has a total of 8 days and 14 hours in space, including 2 hours and 48 minutes walking on the Moon. In March 1966 he was commander of the Gemini 8

  14. Skin findings in Williams syndrome.

    Science.gov (United States)

    Kozel, Beth A; Bayliss, Susan J; Berk, David R; Waxler, Jessica L; Knutsen, Russell H; Danback, Joshua R; Pober, Barbara R

    2014-09-01

    Previous examination in a small number of individuals with Williams syndrome (also referred to as Williams-Beuren syndrome) has shown subtly softer skin and reduced deposition of elastin, an elastic matrix protein important in tissue recoil. No quantitative information about skin elasticity in individuals with Williams syndrome is available; nor has there been a complete report of dermatologic findings in this population. To fill this knowledge gap, 94 patients with Williams syndrome aged 7-50 years were recruited as part of the skin and vascular elasticity (WS-SAVE) study. They underwent either a clinical dermatologic assessment by trained dermatologists (2010 WSA family meeting) or measurement of biomechanical properties of the skin with the DermaLab™ suction cup (2012 WSA family meeting). Clinical assessment confirmed that soft skin is common in this population (83%), as is premature graying of the hair (80% of those 20 years or older), while wrinkles (92%), and abnormal scarring (33%) were detected in larger than expected proportions. Biomechanical studies detected statistically significant differences in dP (the pressure required to lift the skin), dT (the time required to raise the skin through a prescribed gradient), VE (viscoelasticity), and E (Young's modulus) relative to matched controls. The RT (retraction time) also trended longer but was not significant. The biomechanical differences noted in these patients did not correlate with the presence of vascular defects also attributable to elastin insufficiency (vascular stiffness, hypertension, and arterial stenosis) suggesting the presence of tissue specific modifiers that modulate the impact of elastin insufficiency in each tissue. © 2014 Wiley Periodicals, Inc.

  15. Listening to the Voice of Silences: Animism in Jeannette Armstrong's Breath Tracks

    OpenAIRE

    Kina, Ikue; 喜納, 育江

    2003-01-01

    Jeannette Armstrong は、アメリカのワシントン州とカナダのブリティッシュコロンビア州の境界に生きるオカナガン先住民族の書き手である。1990年の詩集 Breath Tracks において、彼女は、先住民としてその生まれ育った大地とそこに生きる様々な生命とどのように関わり合い、生きてきたかを描いているが、その関係性を描くための素地となる Armstrong の自然観には、先住民族が伝統的に育んできたアニミズムという自然観が反映されている。本稿では、David Abram の言語論に言及しながら、アニミズムという自然観がつくりだす詩的言語の可能性について、Armstrong 自身の発言と、Breath Tracks にある数編の詩を中心に考察していく。特に、Breath Tracks に頻出する「沈黙」に着日し、自然界において人間には知覚できない「自然の言語」を、先住民の書き手として Armstrong がどのように言語化しているか、そして、その言諦化のプロセスの中で、Abramの説く「身体的言語(bodily language)」がどのような形で表出しているかにつ...

  16. Multi-Vehicle Cooperative Control Research at the NASA Armstrong Flight Research Center, 2000-2014

    Science.gov (United States)

    Hanson, Curt

    2014-01-01

    A brief introductory overview of multi-vehicle cooperative control research conducted at the NASA Armstrong Flight Research Center from 2000 - 2014. Both flight research projects and paper studies are included. Since 2000, AFRC has been almost continuously pursuing research in the areas of formation flight for drag reduction and automated cooperative trajectories. An overview of results is given, including flight experiments done on the FA-18 and with the C-17. Other multi-vehicle cooperative research is discussed, including small UAV swarming projects and automated aerial refueling.

  17. Neil Armstrong talks of his experiences at Apollo 11 anniversary banquet

    Science.gov (United States)

    1999-01-01

    Neil Armstrong, former Apollo 11 astronaut, and first man to walk on the moon, talks about his experiences for an enthusiastic audience at the Apollo/Saturn V Center, part of the KSC Visitor Complex. The occasion was a banquet celebrating the 30th anniversary of the Apollo 11 launch and moon landing, July 16 and July 20, 1969. Among other guests at the banquet were astronauts Wally Schirra, Edwin 'Buzz' Aldrin and Walt Cunningham. Gene Cernan was the last man to walk on the moon.

  18. Former astronauts Schirra and Armstrong visit KSC for STS-83 launch

    Science.gov (United States)

    1997-01-01

    Among the many special NASA STS-83 launch guests who witnessed the liftoff of the Space Shuttle Columbia April 4 were Apollo 7 Commander Walter M. 'Wally' Schirra (left ) and Apollo l1 Commander Neil A. Armstrong. The two former astronauts are posing in front of the Apollo Command and Service Module in the Apollo/Saturn V Center at KSC. Columbia took off from Launch Pad 39A at 2:20:32 p.m. EST to begin the 16-day Microgravity Science Laboratory-1 (MSL-1) mission.

  19. Neural correlates of amusia in williams syndrome.

    Science.gov (United States)

    Lense, Miriam D; Dankner, Nathan; Pryweller, Jennifer R; Thornton-Wells, Tricia A; Dykens, Elisabeth M

    2014-11-21

    Congenital amusia is defined by marked deficits in pitch perception and production. Though historically examined only in otherwise typically developing (TD) populations, amusia has recently been documented in Williams syndrome (WS), a genetic, neurodevelopmental disorder with a unique auditory phenotype including auditory sensitivities and increased emotional responsiveness to music but variable musical skill. The current study used structural T1-weighted magnetic resonance imaging and diffusion tensor imaging to examine neural correlates of amusia in 17 individuals with WS (4 of whom met criteria for amusia). Consistent with findings from TD amusics, amusia in WS was associated with decreased fractional anisotropy (FA) in the right superior longitudinal fasciculus (SLF). The relationship between amusia and FA in the inferior component of the SLF was particularly robust, withstanding corrections for cognitive functioning, auditory sensitivities, or musical training. Though the number of individuals with amusia in the study is small, results add to evidence for the role of fronto-temporal disconnectivity in congenital amusia and suggest that novel populations with developmental differences can provide a window into understanding gene-brain-behavior relationships that underlie musical behaviors.

  20. Neural Correlates of Amusia in Williams Syndrome

    Directory of Open Access Journals (Sweden)

    Miriam D. Lense

    2014-11-01

    Full Text Available Congenital amusia is defined by marked deficits in pitch perception and production. Though historically examined only in otherwise typically developing (TD populations, amusia has recently been documented in Williams syndrome (WS, a genetic, neurodevelopmental disorder with a unique auditory phenotype including auditory sensitivities and increased emotional responsiveness to music but variable musical skill. The current study used structural T1-weighted magnetic resonance imaging and diffusion tensor imaging to examine neural correlates of amusia in 17 individuals with WS (4 of whom met criteria for amusia. Consistent with findings from TD amusics, amusia in WS was associated with decreased fractional anisotropy (FA in the right superior longitudinal fasciculus (SLF. The relationship between amusia and FA in the inferior component of the SLF was particularly robust, withstanding corrections for cognitive functioning, auditory sensitivities, or musical training. Though the number of individuals with amusia in the study is small, results add to evidence for the role of fronto-temporal disconnectivity in congenital amusia and suggest that novel populations with developmental differences can provide a window into understanding gene-brain-behavior relationships that underlie musical behaviors.

  1. Dr. William O. Coffee and his absorption cure for cataract.

    Science.gov (United States)

    Ferry, A P

    1989-08-01

    Dr. William O. Coffee was an ophthalmologist who conducted an office and mail-order practice in the Midwest from the 1880s until 1927. His main stock in trade was a self-discovered absorption cure for a variety of ocular diseases, with particular emphasis on the medical cure of cataracts. Dr. Coffee's career was a checkered one, marked by dubious credentials, exuberant self-promotion, unlikely and exaggerated claims of medical successes, plagiarism, and rejection by the medical "establishment." Certain parallels may be drawn between his activities and some currently observed practices in ophthalmology.

  2. Sustainable Management of Subterranean Termite Populations (Isoptera: Rhinotermitidae) in Armstrong Park, New Orleans, With Durable Baits.

    Science.gov (United States)

    Su, Nan-Yao; Guidry, Eric; Cottone, Carrie

    2016-03-27

    Durable baits, Recruit HD, were installed in 45 Sentricon stations between September 2010 and July 2014 in the 32-acre Armstrong Park, New Orleans. After eliminating all detectable termite colonies in the Park, 6-12 mo elapsed before new activity was detected. Newly invading termite colonies were usually found near the Park border or were smaller colonies that originated from recently paired alates. After colony elimination, Recruit HD baits were left in the stations to intercept newly invading colonies of subterranean termites, leading to their elimination, and multiple cycles of such interception and elimination events were recorded. Because the presence of Recruit HD baits continues to eliminate incoming colonies with little effort in maintaining and resupplying baits in the target areas, the bait system offers an economically sustainable option for managing subterranean termite populations in a large area. The 32-acre Armstrong Park is a manageable size to carry out an area-wide (AW) project. If the number of such AW projects is gradually increased over time in selected metro areas of New Orleans, we predict that we may be able to turn the tide against the ever-increasing populations ofC. formosanusin the entire city. © The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. A human neurodevelopmental model for Williams syndrome.

    Science.gov (United States)

    Chailangkarn, Thanathom; Trujillo, Cleber A; Freitas, Beatriz C; Hrvoj-Mihic, Branka; Herai, Roberto H; Yu, Diana X; Brown, Timothy T; Marchetto, Maria C; Bardy, Cedric; McHenry, Lauren; Stefanacci, Lisa; Järvinen, Anna; Searcy, Yvonne M; DeWitt, Michelle; Wong, Wenny; Lai, Philip; Ard, M Colin; Hanson, Kari L; Romero, Sarah; Jacobs, Bob; Dale, Anders M; Dai, Li; Korenberg, Julie R; Gage, Fred H; Bellugi, Ursula; Halgren, Eric; Semendeferi, Katerina; Muotri, Alysson R

    2016-08-18

    Williams syndrome is a genetic neurodevelopmental disorder characterized by an uncommon hypersociability and a mosaic of retained and compromised linguistic and cognitive abilities. Nearly all clinically diagnosed individuals with Williams syndrome lack precisely the same set of genes, with breakpoints in chromosome band 7q11.23 (refs 1-5). The contribution of specific genes to the neuroanatomical and functional alterations, leading to behavioural pathologies in humans, remains largely unexplored. Here we investigate neural progenitor cells and cortical neurons derived from Williams syndrome and typically developing induced pluripotent stem cells. Neural progenitor cells in Williams syndrome have an increased doubling time and apoptosis compared with typically developing neural progenitor cells. Using an individual with atypical Williams syndrome, we narrowed this cellular phenotype to a single gene candidate, frizzled 9 (FZD9). At the neuronal stage, layer V/VI cortical neurons derived from Williams syndrome were characterized by longer total dendrites, increased numbers of spines and synapses, aberrant calcium oscillation and altered network connectivity. Morphometric alterations observed in neurons from Williams syndrome were validated after Golgi staining of post-mortem layer V/VI cortical neurons. This model of human induced pluripotent stem cells fills the current knowledge gap in the cellular biology of Williams syndrome and could lead to further insights into the molecular mechanism underlying the disorder and the human social brain.

  4. Language and Communicative Development in Williams Syndrome

    Science.gov (United States)

    Mervis, Carolyn B.; Becerra, Angela M.

    2007-01-01

    Williams syndrome, a genetic disorder caused by a microdeletion of approximately 25 genes on chromosome 7q11.23, is associated with mild to moderate intellectual disability or learning difficulties. Most individuals with Williams syndrome evidence a cognitive profile including relative strengths in verbal short-term memory and language, and…

  5. Williams Syndrome with a “Twist”

    Directory of Open Access Journals (Sweden)

    Despoina Maritsi

    2010-01-01

    Full Text Available Williams syndrome is a rare genetic condition with multisystemic involvement, caused by a microscopic deletion in the chromosome band 7q11.23. We describe the first case of a toddler with Williams syndrome who developed Benign Paroxysmal Torticollis (BPT, a benign dystonic disorder of unknown aetiology.

  6. A Fresh Look at Flooring Costs. A Report on a Survey of User Experience Compiled by Armstrong Cork Company.

    Science.gov (United States)

    Armstrong Cork Co., Lancaster, PA.

    Survey information based on actual flooring installations in several types of buildings and traffic conditions, representing nearly 113 million square feet of actual user experience, is contained in this comprehensive report compiled by the Armstrong Cork Company. The comparative figures provided by these users clearly establish that--(1) the…

  7. Use of the Published Lance Armstrong Cancer Story to Teach Health Science Content to High School Students

    Science.gov (United States)

    Burns, E. Robert

    2008-01-01

    Lance Armstrong (2000) authored a book titled "It's Not About the Bike -- My Journey Back to Life," regarding his battle with testicular cancer. It became a "New York Times" Bestseller and was selected by the "School Library Journal" as one of the "Best Adult Books for High School Students for 2001." The goal of the project described in this…

  8. 75 FR 57974 - Senior Executive Service Performance Review Board

    Science.gov (United States)

    2010-09-23

    .... Crocetti Jr., Louis D. Cullen, Susan M. Cummiskey, Chris Daitch, William Davis, Delia P. Dayton, Mark de.... Armstrong, Charles R. Ayala, Janice Aytes, Michael L. Bacon, Roxana Baldwin, William D. Baroukh, Nader Barr... Brundage, William Bucella, Donna A. Bucher, Steven P. Buckingham, Patricia A. Burke, Richard Butcher...

  9. Using Airborne In-Situ Profiles to Evaluate TCCON Data from Armstrong Flight Research Center

    Science.gov (United States)

    Iraci, L. T.; Hillyard, P. W.; Podolske, J. R.; Roehl, C. M.; Wunch, D.; Wennberg, P. O.; Albertson, R.

    2016-12-01

    A Fourier Transform Spectrometer (FTS) was deployed to the Armstrong Flight Research Center (AFRC) in Edwards, CA as a member of the Total Carbon Column Observing Network (TCCON) and has now been in operation for over 3 years. The data record from AFRC will be presented as well as airborne validation profiles obtained during the NASA SEAC4RS, SARP, KORUS-AQ, and ATom missions utilizing various NASA aircraft. One of the reasons that the AFRC location was selected is due to its proximity to a highly reflective lakebed, which has proven to be difficult for accurate satellite retrievals. As such, the data from AFRC has been used for OCO-2 calibration. In order for accurate calibration of OCO-2, the validity of the TCCON measurements must be established. To this end, integrated airborne in-situ vertical profiles will be presented and compared with the TCCON FTS measurements, where good agreement has been found.

  10. Reconfiguring trade mark law

    DEFF Research Database (Denmark)

    Elsmore, Matthew James

    2013-01-01

    -border setting, with a particular focus on small business and consumers. The article's overall message is to call for a rethink of received wisdom suggesting that trade marks are effective trade-enabling devices. The case is made for reassessing how we think about European trade mark law.......First, this article argues that trade mark law should be approached in a supplementary way, called reconfiguration. Second, the article investigates such a reconfiguration of trade mark law by exploring the interplay of trade marks and service transactions in the Single Market, in the cross...

  11. William Paley's lost "intelligent design".

    Science.gov (United States)

    Shapiro, Adam R

    2009-01-01

    William Paley's Natural Theology has experienced a resurgence in popularity in recent decades with the continuing controversies over the teaching of evolution and the emergence of a new "intelligent design" movement. But while both the movement's supporters and detractors agree that Paley is an intellectual forefather of the present-day movement, this agreement is forged at the expense of historical accuracy. Paley's intelligent design has almost nothing in common with the present day movement and, in fact, suggests theological arguments against the type of reasoning used by the modern movement. Paley wrote in reaction to Hume and in response to the evolutionary theories of Buffon and Erasmus Darwin. In this light, the Natural Theology suggests a different reading than it is usually given. Paley's narrowly-argued theology relies upon the ability to detect the presence of "purpose" in nature without relying upon knowing what those purposes are. His empirically-argued theology leads him to a God who operates through natural law, not in its contravention, and his concern goes far beyond proving the existence of a deity to undertaking the theological project of determining the attributes and characteristics of the deity. Though not himself an evolutionist, Paley put forth a theological worldview consistent with evolution. In fact, given his arguments that the observation of great contrivance increases the testimony of nature to God's power, Paley's philosophy might be more consistent with a theistic Darwinian evolution than with special creation.

  12. David Owen Williams (1944 - 2006)

    CERN Multimedia

    2006-01-01

    Many people, not only at CERN but also throughout the world, were saddened to learn that their friend and colleague David Williams had passed away in the early hours of Tuesday 24 October. His death came after a year of fighting cancer with all of his usual determination and optimism. Even days before the end he was still welcoming to visitors, and was alert and interested in all their news. Born in 1944, David came to CERN from the University of Cambridge in 1966, with a degree in Physics and Computer Science. Joining what at the time was called the Documents and Data (DD) Division, in the earlier part his career he worked first on software for analysis of bubble chamber photographs, subsequently leading the group that supported experiments with 'hybrids' of bubble chambers and electronic detectors and then the group supporting online computing in experiments. He thus witnessed all of the enormous changes that took place in particle physics as the era of bubble chambers came to an end and the availability ...

  13. William Harvey, Aristotle and astrology.

    Science.gov (United States)

    Gregory, Andrew

    2014-06-01

    In this paper I argue that William Harvey believed in a form of astrology. It has long been known that Harvey employed a macrocosm-microcosm analogy and used alchemical terminology in describing how the two types of blood change into one another. This paper then seeks to examine a further aspect of Harvey in relation to the magical tradition. There is an important corollary to this line of thought, however. This is that while Harvey does have a belief in astrology, it is strongly related to Aristotle's views in this area and is quite restricted and attenuated relative to some contemporary beliefs in astrology. This suggests a more general thesis. While Harvey was amenable to ideas which we associate with the natural magic tradition, those ideas had a very broad range of formulation and there was a limit to how far he would accept them. This limit was largely determined by Harvey's adherence to Aristotle's natural philosophy and his Christian beliefs. I argue that this is also the case in relation to Harvey's use of the macrocosm-microcosm analogy and of alchemical terminology, and, as far as we can rely on the evidence, this informs his attitudes towards witches as well. Understanding Harvey's influences and motives here is important in placing him properly in the context of early seventeenth-century thought.

  14. Prince William Sound, Alaska ESI: HYDRO (Hydrology)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  15. Prince William Sound, Alaska ESI: INVERT (Invertebrates)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  16. Prince William Sound, Alaska ESI: INDEX

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  17. 33 CFR 167.1700 - In Prince William Sound: General.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false In Prince William Sound: General... Schemes and Precautionary Areas Pacific West Coast § 167.1700 In Prince William Sound: General. The Prince William Sound Traffic Separation Scheme consists of four parts: Prince William Sound Traffic Separation...

  18. Mark Tompkins Canaccord

    OpenAIRE

    Mark Tompkins Canaccord

    2018-01-01

    Mark Tompkins Canaccord is a senior technologist for ecosystem and water resources management in SEC SAID Oakland, California office. In his career which lasts over fifteen years Mark has worked on project involving lake restorations, clean water engineering, ecological engineering and management, hydrology, hydraulics, sediment transport and other projects for environmental planning all over the country. Mark Tompkins Canaccord tries to blend his skills of planning and engineering with s...

  19. Colour discrimination and categorisation in Williams syndrome

    OpenAIRE

    Farran, E. K.; Cranwell, M. B.; Alvarez, J.; Franklin, A.

    2013-01-01

    Individuals with Williams syndrome (WS) present with impaired functioning of the dorsal visual stream relative to the ventral visual stream. As such, little attention has been given to ventral stream functions in WS. We investigated colour processing, a predominantly ventral stream function, for the first time in nineteen individuals with Williams syndrome. Colour discrimination was assessed using the Farnsworth-Munsell 100 hue test. Colour categorisation was assessed using a match-to-sample ...

  20. Thomas Armstrong (2012: El poder de la neurodiversidad. Las extraordinarias capacidades que se ocultan tras el autismo, la hiperactividad, la dislexia y otras diferencias cerebrales. Barcelona: Espasa Libros.

    Directory of Open Access Journals (Sweden)

    Ángela María Lopera Murcia

    2017-06-01

    Full Text Available Reseña de la obra 'El poder de la neurodiversidad. Las extraordinarias capacidades que se ocultan tras el autismo, la hiperactividad, la dislexia y otras diferencias cerebrales' (2012 de Thomas Armstrong.

  1. Thomas Armstrong (2012): El poder de la neurodiversidad. Las extraordinarias capacidades que se ocultan tras el autismo, la hiperactividad, la dislexia y otras diferencias cerebrales. Barcelona: Espasa Libros.

    OpenAIRE

    Ángela María Lopera Murcia

    2017-01-01

    Reseña de la obra 'El poder de la neurodiversidad. Las extraordinarias capacidades que se ocultan tras el autismo, la hiperactividad, la dislexia y otras diferencias cerebrales' (2012) de Thomas Armstrong.

  2. Lujan Mark-4

    Energy Technology Data Exchange (ETDEWEB)

    Mocko, Michael Jeffrey [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Zavorka, Lukas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Koehler, Paul E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-11-13

    This is a review of Mark-IV target neutronics design. It involved the major redesign of the upper tier, offering harder neutron spectra for upper-tier FPs; a redesign of the high-resolution (HR) moderator; and a preservation of the rest of Mark-III features.

  3. Mark Stock | NREL

    Science.gov (United States)

    Stock Mark Stock Scientific Visualization Specialist Mark.Stock@nrel.gov | 303-275-4174 Dr. Stock , virtual reality, parallel computing, and manipulation of large spatial data sets. As an artist, he creates . Stock built the SUNLIGHT artwork that is installed on the Webb Building in downtown Denver. In addition

  4. Summer Research Program (1992). Summer Faculty Research Program (SFRP) Reports. Volume 2. Armstrong Laboratory

    Science.gov (United States)

    1992-12-01

    Comparison of Alternative Multiship Aircraft Simulation Dr. William C. Moor Systems Utilizing Benefit Estimation 27 Vocalizations of Naturally Ranging Groups...binocular display devices, like miost of thie llead-Mounited Displays.we can presetnt different visual stimulus to two hiuman eye channels. In p~ articular ...Menus -requires more complex -should minimise user programming programming -should be straightforward -shouldn’t distract driver -workload shouldn’t be

  5. Documenting the NASA Armstrong Flight Research Center Oblate Earth Simulation Equations of Motion and Integration Algorithm

    Science.gov (United States)

    Clarke, R.; Lintereur, L.; Bahm, C.

    2016-01-01

    A desire for more complete documentation of the National Aeronautics and Space Administration (NASA) Armstrong Flight Research Center (AFRC), Edwards, California legacy code used in the core simulation has led to this e ort to fully document the oblate Earth six-degree-of-freedom equations of motion and integration algorithm. The authors of this report have taken much of the earlier work of the simulation engineering group and used it as a jumping-o point for this report. The largest addition this report makes is that each element of the equations of motion is traced back to first principles and at no point is the reader forced to take an equation on faith alone. There are no discoveries of previously unknown principles contained in this report; this report is a collection and presentation of textbook principles. The value of this report is that those textbook principles are herein documented in standard nomenclature that matches the form of the computer code DERIVC. Previous handwritten notes are much of the backbone of this work, however, in almost every area, derivations are explicitly shown to assure the reader that the equations which make up the oblate Earth version of the computer routine, DERIVC, are correct.

  6. A study of the Armstrong Whitworth swing beam engine for automotive application

    Science.gov (United States)

    1983-01-01

    The introduction of ceramics to those parts suffering high thermal loading was successfully demonstrated, and there is no question that the 100 kw (134 hp) naturally aspirated engine of the future will be developed to produce up to 300 kw (402 hp) by the application of turbocharging or its equivalent. However, at the 60 - 80 kw (80 - 107 hp) size needed for the economic automotive engine, scaling down the 300 kw (402 hp) is beset by the laws of scale. The conventional four stroke diesel was not shown to be successful at the small high speed engine size. The opposed piston two stroke engine does not suffer the same laws of scale and engines in the low power range have already been marketed successfully. The half liter/cylinder Armstrong Whitworth Swing Beam Engine is the latest to be designed with the automotive market in mind. Its low noise structure and balanced linkage system coupled with advantages for easy start and potential use of low grade fuels, derived from its variable compression ratio and slow piston motion, qualifies it for the application.

  7. Calibration of a TCCON FTS at Armstrong Flight Research Center (AFRC) Using Multiple Airborne Profiles

    Science.gov (United States)

    Hillyard, P. W.; Iraci, L. T.; Podolske, J. R.; Tanaka, T.; Yates, E. L.; Roehl, C. M.; Wunch, D.; Wennberg, P. O.; Albertson, R. T.; Blake, D. R.; Meinardi, S.; Marrero, J. E.; Yang, M. M.; Beyersdorf, A. J.; Wofsy, S. C.; Pittman, J. V.; Daube, B. C.

    2014-12-01

    Satellite missions including GOSAT, OCO-2 and ASCENDS measure column abundances of greenhouse gases. It is crucial to have calibrated ground-based measurements to which these satellite measurements can compare and refine their retrieval algorithms. To this end, a Fourier Transform Spectrometer has been deployed to the Armstrong Flight Research Center (AFRC) in Edwards, CA as a member of the Total Carbon Column Observing Network (TCCON). This location was selected due to its proximity to a highly reflective lakebed. Such surfaces have proven to be difficult for accurate satellite retrievals. This facility has been in operation since July 2013. The data collected to date at this site will be presented. In order to ensure the validity of the measurements made at this site, multiple vertical profiles have been performed using the Alpha jet, DC-8, and ER-2 as part of the AJAX (ongoing), SEAC4RS (August 2013), and SARP (July 2014) field campaigns. The integrated in-situ vertical profiles for CO2 and CH4 have been analyzed and compared with the TCCON FTS measurements, where good agreement between TCCON data and vertically-integrated aircraft in-situ data has been found.

  8. The Armstrong Institute: An Academic Institute for Patient Safety and Quality Improvement, Research, Training, and Practice.

    Science.gov (United States)

    Pronovost, Peter J; Holzmueller, Christine G; Molello, Nancy E; Paine, Lori; Winner, Laura; Marsteller, Jill A; Berenholtz, Sean M; Aboumatar, Hanan J; Demski, Renee; Armstrong, C Michael

    2015-10-01

    Academic medical centers (AMCs) could advance the science of health care delivery, improve patient safety and quality improvement, and enhance value, but many centers have fragmented efforts with little accountability. Johns Hopkins Medicine, the AMC under which the Johns Hopkins University School of Medicine and the Johns Hopkins Health System are organized, experienced similar challenges, with operational patient safety and quality leadership separate from safety and quality-related research efforts. To unite efforts and establish accountability, the Armstrong Institute for Patient Safety and Quality was created in 2011.The authors describe the development, purpose, governance, function, and challenges of the institute to help other AMCs replicate it and accelerate safety and quality improvement. The purpose is to partner with patients, their loved ones, and all interested parties to end preventable harm, continuously improve patient outcomes and experience, and eliminate waste in health care. A governance structure was created, with care mapped into seven categories, to oversee the quality and safety of all patients treated at a Johns Hopkins Medicine entity. The governance has a Patient Safety and Quality Board Committee that sets strategic goals, and the institute communicates these goals throughout the health system and supports personnel in meeting these goals. The institute is organized into 13 functional councils reflecting their behaviors and purpose. The institute works daily to build the capacity of clinicians trained in safety and quality through established programs, advance improvement science, and implement and evaluate interventions to improve the quality of care and safety of patients.

  9. Williams-Beuren's Syndrome: A Case Report.

    Science.gov (United States)

    Zamani, Hassan; Babazadeh, Kazem; Fattahi, Saeid; Mokhtari-Esbuie, Farzad

    2012-01-01

    Williams-Beuren syndrome is a rare familial multisystem disorder occurring in 1 per 20,000 live births. It is characterized by congenital heart defects (CHD), skeletal and renal anomalies, cognitive disorder, social personality disorder and dysmorphic facies. We present a case of Williams syndrome that presented to us with heart murmur and cognitive problem. A 5-year-old girl referred to pediatric cardiologist because of heart murmurs. She had a systolic murmur (2-3/6) in right upper sternal border with radiation to right cervical region. She also had a bulge forehead. Angiography showed mild supra valvular aortic stenosis and mild multiple peripheral pulmonary stenosis. Fluorescent in situ hybridization (FISH) was performed and the result was: 46.XX, ish del (7q11.2) (ELN X1) (7q22 X2) ELN deletion compatible with Williams syndrome. Peripheral pulmonary artery stenosis is associated with Noonan syndrome, Alagille syndrome, Cutis laxa, Ehler-Danlos syndrome, and Silver-Russel syndrome. The patient had peripheral pulmonary artery stenosis, but no other signs of these syndromes were present, and also she had a supravalvular aortic stenosis which was not seen in other syndromes except Williams syndrome. Conclusion. According to primary symptoms, paraclinical and clinical finding such as dysmorphic facies, cognitive disorder and congenital heart defect, Williams syndrome was the first diagnosis. We suggest a more attention for evaluating heart murmur in childhood period, especially when the patient has abnormal facial features or mental problem.

  10. Williams-Beuren's Syndrome: A Case Report

    Directory of Open Access Journals (Sweden)

    Hassan Zamani

    2012-01-01

    Full Text Available Williams-Beuren syndrome is a rare familial multisystem disorder occurring in 1 per 20,000 live births. It is characterized by congenital heart defects (CHD, skeletal and renal anomalies, cognitive disorder, social personality disorder and dysmorphic facies. We present a case of Williams syndrome that presented to us with heart murmur and cognitive problem. A 5-year-old girl referred to pediatric cardiologist because of heart murmurs. She had a systolic murmur (2-3/6 in right upper sternal border with radiation to right cervical region. She also had a bulge forehead. Angiography showed mild supra valvular aortic stenosis and mild multiple peripheral pulmonary stenosis. Fluorescent in situ hybridization (FISH was performed and the result was: 46.XX, ish del (7q11.2 (ELN X1 (7q22 X2 ELN deletion compatible with Williams syndrome. Peripheral pulmonary artery stenosis is associated with Noonan syndrome, Alagille syndrome, Cutis laxa, Ehler-Danlos syndrome, and Silver-Russel syndrome. The patient had peripheral pulmonary artery stenosis, but no other signs of these syndromes were present, and also she had a supravalvular aortic stenosis which was not seen in other syndromes except Williams syndrome. Conclusion. According to primary symptoms, paraclinical and clinical finding such as dysmorphic facies, cognitive disorder and congenital heart defect, Williams syndrome was the first diagnosis. We suggest a more attention for evaluating heart murmur in childhood period, especially when the patient has abnormal facial features or mental problem.

  11. Social Cognition in Williams Syndrome: Face Tuning.

    Science.gov (United States)

    Pavlova, Marina A; Heiz, Julie; Sokolov, Alexander N; Barisnikov, Koviljka

    2016-01-01

    Many neurological, neurodevelopmental, neuropsychiatric, and psychosomatic disorders are characterized by impairments in visual social cognition, body language reading, and facial assessment of a social counterpart. Yet a wealth of research indicates that individuals with Williams syndrome exhibit remarkable concern for social stimuli and face fascination. Here individuals with Williams syndrome were presented with a set of Face-n-Food images composed of food ingredients and in different degree resembling a face (slightly bordering on the Giuseppe Arcimboldo style). The primary advantage of these images is that single components do not explicitly trigger face-specific processing, whereas in face images commonly used for investigating face perception (such as photographs or depictions), the mere occurrence of typical cues already implicates face presence. In a spontaneous recognition task, participants were shown a set of images in a predetermined order from the least to most resembling a face. Strikingly, individuals with Williams syndrome exhibited profound deficits in recognition of the Face-n-Food images as a face: they did not report seeing a face on the images, which typically developing controls effortlessly recognized as a face, and gave overall fewer face responses. This suggests atypical face tuning in Williams syndrome. The outcome is discussed in the light of a general pattern of social cognition in Williams syndrome and brain mechanisms underpinning face processing.

  12. Mark 1 Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Mark I Test Facility is a state-of-the-art space environment simulation test chamber for full-scale space systems testing. A $1.5M dollar upgrade in fiscal year...

  13. Mark Raidpere portreefotod Kielis

    Index Scriptorium Estoniae

    1999-01-01

    Kieli Linnagaleriis avatud 2. Ars Baltica fototriennaalil 'Can You Hear Me?' esindab Eestit Mark Raidpere seeriaga 'Portreed 1998'. Näituse Eesti-poolne kuraator Anu Liivak, kataloogiteksti kirjutas Anders Härm. Tuntumaid osalejaid triennaalil Wolfgang Tillmans

  14. Marks of Metal Copenhell

    DEFF Research Database (Denmark)

    2015-01-01

    Planchebaseret udendørs udstilling på musikfestivalen Copenhell 18-20/6 2015. En mindre udgave af udstillingen Marks of Metal - Logodesign og visualitet i heavy metal. Udarbejdet i samarbejde med Mediemuseet.......Planchebaseret udendørs udstilling på musikfestivalen Copenhell 18-20/6 2015. En mindre udgave af udstillingen Marks of Metal - Logodesign og visualitet i heavy metal. Udarbejdet i samarbejde med Mediemuseet....

  15. COMPUTER HARDWARE MARKING

    CERN Multimedia

    Groupe de protection des biens

    2000-01-01

    As part of the campaign to protect CERN property and for insurance reasons, all computer hardware belonging to the Organization must be marked with the words 'PROPRIETE CERN'.IT Division has recently introduced a new marking system that is both economical and easy to use. From now on all desktop hardware (PCs, Macintoshes, printers) issued by IT Division with a value equal to or exceeding 500 CHF will be marked using this new system.For equipment that is already installed but not yet marked, including UNIX workstations and X terminals, IT Division's Desktop Support Service offers the following services free of charge:Equipment-marking wherever the Service is called out to perform other work (please submit all work requests to the IT Helpdesk on 78888 or helpdesk@cern.ch; for unavoidable operational reasons, the Desktop Support Service will only respond to marking requests when these coincide with requests for other work such as repairs, system upgrades, etc.);Training of personnel designated by Division Leade...

  16. Investigating the ''social brain'' through Williams syndrome

    International Nuclear Information System (INIS)

    Nagamine, Masanori; Mimura, Masaru; Reiss, A.L.; Hoeft, F.

    2010-01-01

    Recent advances in social cognitive neuroscience have led to the concept of the ''social brain''. The social brain includes neural processes specialized for processing social information necessary for the recognition of self and others, and interpersonal relationships. Because of its unique behavioral phenotypic features which includes 'hypersociability', Williams syndrome has gained popularity among social cognitive neuroscientists. Individuals with Williams syndrome share the same genetic risk factor for cognitive-behavioral dysfunction utilizing brain imaging to elucidate endophenotype provides us with an unprecendented opportunity to study gene, brain and behavior relationships especially those related to social cognition. In this review, we provide an overview of neuroimaging studies on social cognition in Williams syndrome and discuss the neural basis of the social brain. (author)

  17. William Carlos Williams’ cubism: The sensory dimension

    Directory of Open Access Journals (Sweden)

    J-L Kruger

    1995-05-01

    Full Text Available In this article the cubism of the American poet William Carlos Williams is discussed as a product of sensory elements combined with techniques derived from the work of the visual artists associated with this style. Through the study o f a number of poems written in the period between 1917 and 1923 it is shown that Williams employs the cubist intersection of sensory planes in particular to create a sensory dimension that not only renews the traditions and mode of poetry, but also reveals the cubist concern with the defamiliarization and foregrounding of fragments of everyday experiences. Ultimately the article is an attempt to indicate Williams’ incorporation o f a sensual dimension in creating a style that achieves modernist presentation revealing an independence from both traditional literary and visual styles.

  18. [Association between Williams syndrome and adrenal insufficiency].

    Science.gov (United States)

    Rchachi, Meryem; Larwanou, Maazou Mahamane; El Ouahabi, Hanan; Ajdi, Farida

    2017-01-01

    Williams syndrome is a developmental disorder including dysmorphia, cardiovascular malformations and a specific neuropsychological profile together with other associated disorders. We report the case of a 17-year old girl, born of a non-inbred marriage, with Williams syndrome discovered during an assessment of degree of failure to thrive. Its association with primary adrenal insufficiency makes it unique. Diagnosis is confirmed by cytogenetic and molecular analysis. Its management consists of the implementation of treatment for adrenal insufficiency associated with a clinico-biological monitoring.

  19. Landscape consequences of natural gas extraction in Armstrong and Indiana Counties, Pennsylvania, 2004–2010

    Science.gov (United States)

    Slonecker, Terry E.; Milheim, Lesley E.; Roig-Silva, Coral M.; Malizia, Alexander R.

    2013-01-01

    Increased demands for cleaner burning energy, coupled with the relatively recent technological advances in accessing unconventional hydrocarbon-rich geologic formations, have led to an intense effort to find and extract natural gas from various underground sources around the country. One of these sources, the Marcellus Shale, located in the Allegheny Plateau, is currently undergoing extensive drilling and production. The technology used to extract gas in the Marcellus Shale is known as hydraulic fracturing and has garnered much attention because of its use of large amounts of fresh water, its use of proprietary fluids for the hydraulic-fracturing process, its potential to release contaminants into the environment, and its potential effect on water resources. Nonetheless, development of natural gas extraction wells in the Marcellus Shale is only part of the overall natural gas story in this area of Pennsylvania. Conventional natural gas wells are commonly located in the same general area as the Marcellus Shale and are frequently developed in clusters across the landscape. The combined effects of these two natural gas extraction methods create potentially serious patterns of disturbance on the landscape. This document quantifies the landscape changes and consequences of natural gas extraction for Armstrong County and Indiana County in Pennsylvania between 2004 and 2010. Patterns of landscape disturbance related to natural gas extraction activities were collected and digitized using National Agriculture Imagery Program (NAIP) imagery for 2004, 2005/2006, 2008, and 2010. The disturbance patterns were then used to measure changes in land cover and land use using the National Land Cover Database (NLCD) of 2001. A series of landscape metrics is also used to quantify these changes and is included in this publication.

  20. Augmented marked graphs

    CERN Document Server

    Cheung, King Sing

    2014-01-01

    Petri nets are a formal and theoretically rich model for the modelling and analysis of systems. A subclass of Petri nets, augmented marked graphs possess a structure that is especially desirable for the modelling and analysis of systems with concurrent processes and shared resources.This monograph consists of three parts: Part I provides the conceptual background for readers who have no prior knowledge on Petri nets; Part II elaborates the theory of augmented marked graphs; finally, Part III discusses the application to system integration. The book is suitable as a first self-contained volume

  1. The world in eighteen lessons: Christopher Williams

    NARCIS (Netherlands)

    Berrebi, S.

    2011-01-01

    Conceptual photographer Christopher Williams is a real artist's artist. Ever since he moved to Germany, his measured work, which both reveres and examines the art of photography, has more and more easily found its way into European art institutes, such as this spring at Museum Dhondt-Dhaenens in

  2. De wereld in 18 lessen: Christopher Williams

    NARCIS (Netherlands)

    Berrebi, S.

    2011-01-01

    Hij is een echte artist’s artist, de conceptuele fotograaf Christopher Williams. Sinds hij in Duitsland woont en werkt, vindt zijn afgewogen werk, dat de fotografie tegelijk eert en ondervraagt, steeds makkelijker onderdak in Europese kunstinstituten, zoals dit voorjaar bij Museum Dhondt-Dhaenens in

  3. March 1964 Prince William Sound, USA Images

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Prince William Sound magnitude 9.2 Mw earthquake on March 28, 1964 at 03:36 GMT (March 27 at 5:36 pm local time), was the largest U.S. earthquake ever recorded...

  4. Fears, Hyperacusis and Musicality in Williams Syndrome

    Science.gov (United States)

    Blomberg, Stefan; Rosander, Michael; Andersson, Gerhard

    2006-01-01

    The study investigated the prevalence of fear and hyperacusis and the possible connections between fear, hyperacusis and musicality in a Swedish sample of individuals with Williams syndrome (WS). The study included 38 individuals and a cross-sectional design, with no matched control group. Two persons, who knew the participant well, completed a…

  5. Psycholinguistic Abilities of Children with Williams Syndrome

    Science.gov (United States)

    Rossi, Natalia F.; Heinze, Elena Garayzabal; Giacheti, Celia M.; Goncalves, Oscar F.; Sampaio, Adriana

    2012-01-01

    The objective of this study was to investigate the psycholinguistic abilities of children with Williams syndrome (WS) and typically developing children using the Illinois Test of Psycholinguistic Abilities (ITPA). Performance on the ITPA was analysed in a group with WS (N=20, mean age=8.5 years, SD=1.62) and two typically developing groups,…

  6. Who Was the Real William Shakespeare?

    Science.gov (United States)

    Edwards, Michael Todd

    2009-01-01

    This article highlights a project that encourages students to connect reading and mathematics instruction by using a data analysis approach. Students analyze sonnets from statistical, literary, and historical points of view in an effort to uncover the true identity of William Shakespeare. (Contains 10 figures.)

  7. Florence Jessie Mac Williams (1917-1990)

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 10; Issue 1. Florence Jessie Mac Williams (1917-1990). Featured Scientist Volume 10 Issue 1 January 2005 pp 98-98. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/010/01/0098-0098. Resonance ...

  8. Denigrating Carl Rogers: William Coulson's Last Crusade.

    Science.gov (United States)

    Kirschenbaum, Howard

    1991-01-01

    Reviews William Coulson's assertions that Carl Rogers, Abraham Maslow, and he initiated the humanistic education field, that Rogers repudiated his philosophy late in life, and that they owe the nation's parents an apology. Argues that these charges are groundless and provides examples and quotations from Rogers' later writings to show how Rogers…

  9. Mr. William Shakespeare and the Internet.

    Science.gov (United States)

    Reeves, Barbara

    2000-01-01

    Describes resources and links on a Web site entitled "Mr. William Shakespeare and the Internet," with suggestions for using them with students. Highlights include: historical context; impact of events/situations on works; motivational/preparatory lessons; reading and understanding Shakespeare; analysis of works; language; assessing other…

  10. MRI Amygdala Volume in Williams Syndrome

    Science.gov (United States)

    Capitao, Liliana; Sampaio, Adriana; Sampaio, Cassandra; Vasconcelos, Cristiana; Fernandez, Montse; Garayzabal, Elena; Shenton, Martha E.; Goncalves, Oscar F.

    2011-01-01

    One of the most intriguing characteristics of Williams Syndrome individuals is their hypersociability. The amygdala has been consistently implicated in the etiology of this social profile, particularly given its role in emotional and social behavior. This study examined amygdala volume and symmetry in WS individuals and in age and sex matched…

  11. Analysis of Speech Fluency in Williams Syndrome

    Science.gov (United States)

    Rossi, Natalia Freitas; Sampaio, Adriana; Goncalves, Oscar F.; Giacheti, Celia Maria

    2011-01-01

    Williams syndrome (WS) is a neurodevelopmental genetic disorder, often referred as being characterized by dissociation between verbal and non-verbal abilities, although the number of studies disputing this proposal is emerging. Indeed, although they have been traditionally reported as displaying increased speech fluency, this topic has not been…

  12. Attention to Faces in Williams Syndrome

    Science.gov (United States)

    Riby, Deborah M.; Jones, Nicola; Brown, Philippa H.; Robinson, Lucy J.; Langton, Stephen R. H.; Bruce, Vicki; Riby, Leigh M.

    2011-01-01

    Williams syndrome (WS) is associated with distinct social behaviours. One component of the WS social phenotype is atypically prolonged face fixation. This behaviour co-exists with attention difficulties. Attention is multi-faceted and may impact on gaze behaviour in several ways. Four experiments assessed (i) attention capture by faces, (ii)…

  13. Attentional Disengagement in Adults with Williams Syndrome

    Science.gov (United States)

    Lense, Miriam D.; Key, Alexandra P.; Dykens, Elisabeth M.

    2011-01-01

    Williams syndrome (WS) is a neurodevelopmental disorder characterized by a distinctive behavioral and cognitive profile, including widespread problems with attention. However, the specific nature of their attentional difficulties, such as inappropriate attentional allocation and/or poor attentional disengagement abilities, has yet to be…

  14. Stranger Danger Awareness in Williams Syndrome

    Science.gov (United States)

    Riby, D. M.; Kirk, H.; Hanley, M.; Riby, L. M.

    2014-01-01

    Background: The developmental disorder Williams syndrome (WS) is characterised by a distinctive cognitive profile and an intriguing social phenotype. Individuals with the disorder are often highly social engaging with familiar and unfamiliar people and once in an interaction they often show subtle abnormalities of social behaviour. Atypically…

  15. Fading-Figure Tracing in Williams Syndrome

    Science.gov (United States)

    Nagai, Chiyoko; Inui, Toshio; Iwata, Makoto

    2011-01-01

    Williams syndrome (WS) is a neurodevelopmental disorder characterized by severe impairment of visuospatial abilities. Figure-drawing abilities, which are thought to reflect visuospatial abilities, have yet to be fully investigated in WS. The purpose of the present study was to clarify whether drawing abilities differ between WS individuals and…

  16. Attribution of Negative Intention in Williams Syndrome

    Science.gov (United States)

    Godbee, Kali; Porter, Melanie A.

    2013-01-01

    People with Williams syndrome (WS) are said to have sociable and extremely trusting personalities, approaching strangers without hesitation. This study investigated whether people with WS are less likely than controls to attribute negative intent to others when interpreting a series of ambiguous pictures. This may, at least partially, explain…

  17. Northern gas: Williams petrochemical feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Chappell, D. [Williams Energy Canada, Calgary, AB (Canada)

    2002-07-01

    Williams Energy is a company that is involved in the following fields: gas pipelines, exploration and production, midstream, refining, petrochemical, power, and marketing and trading. The author provides an overview of the global and Canadian infrastructure before proceeding to discuss Arctic gas, which is viewed by Williams Energy as necessary. It favors the Alaska Highway route with a consortium for project development. Williams performed a petrochemical study to determine the feasibility of a petrochemical complex utilizing natural gas liquid from an Arctic gas pipeline. The scope of the study encompassed facilities (extraction plant, cracker, polyolefins plant), size (world scale, approximately 2 billion pounds per year), and location (Fairbanks or Alberta). The study led to the following findings: (1) review of several scenarios for both locations, (2) complex to produce two grades of polyethylene, (3) feedstock cost favors Alaska, (4) construction costs lower in Alberta, (5) and the primary market for the Alaska complex would be northeast Asia, while the primary market for the Alberta location would be the United States. It was determined that both options would be viable, however Alberta was favored due to the polyethylene forecast. The challenges still being faced by Williams include low frac spread, market inefficiencies, empress volumes, carbon dioxide, and fuel and electricity cost. Each of these challenges is discussed separately. The author concludes by indicating that incremental ethane is available, carbon dioxide issues need resolution, and Alberta and Alaska are attractive for Arctic ethane petrochemical production. figs.

  18. Executive Functions in Individuals with Williams Syndrome

    Science.gov (United States)

    Menghini, D.; Addona, F.; Costanzo, F.; Vicari, S.

    2010-01-01

    Background: The present study was aimed at investigating working memory (WM) and executive functions capacities in individuals with Williams syndrome (WS) as compared with mental-age matched typically developing (TD) children. Method: In order to serve the study goal, a sizeable battery of tasks tapping WM as well as attention, memory, planning,…

  19. A Diagnosis to Consider in an Adult Patient with Facial Features and Intellectual Disability: Williams Syndrome.

    Science.gov (United States)

    Doğan, Özlem Akgün; Şimşek Kiper, Pelin Özlem; Utine, Gülen Eda; Alikaşifoğlu, Mehmet; Boduroğlu, Koray

    2017-03-01

    Williams syndrome (OMIM #194050) is a rare, well-recognized, multisystemic genetic condition affecting approximately 1/7,500 individuals. There are no marked regional differences in the incidence of Williams syndrome. The syndrome is caused by a hemizygous deletion of approximately 28 genes, including ELN on chromosome 7q11.2. Prenatal-onset growth retardation, distinct facial appearance, cardiovascular abnormalities, and unique hypersocial behavior are among the most common clinical features. Here, we report the case of a patient referred to us with distinct facial features and intellectual disability, who was diagnosed with Williams syndrome at the age of 37 years. Our aim is to increase awareness regarding the diagnostic features and complications of this recognizable syndrome among adult health care providers. Williams syndrome is usually diagnosed during infancy or childhood, but in the absence of classical findings, such as cardiovascular anomalies, hypercalcemia, and cognitive impairment, the diagnosis could be delayed. Due to the multisystemic and progressive nature of the syndrome, accurate diagnosis is critical for appropriate care and screening for the associated morbidities that may affect the patient's health and well-being.

  20. Identification markings for gemstones

    International Nuclear Information System (INIS)

    Dreschhoff, G.A.M.; Zeller, E.J.

    1980-01-01

    A method is described of providing permanent identification markings to gemstones such as diamond crystals by irradiating the cooled gemstone with protons in the desired pattern. The proton bombardment results in a reaction limited to a defined plane and converting the bombarded area of the plane into a different crystal lattice from that of the preirradiated stone. (author)

  1. 76 FR 1130 - Prince William Sound Resource Advisory Committee

    Science.gov (United States)

    2011-01-07

    ... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... conducted: The Prince William Sound Resource Advisory Committee (RAC) will be discussing and voting on...

  2. 76 FR 18715 - Prince William Sound Resource Advisory Committee

    Science.gov (United States)

    2011-04-05

    ... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... meeting is open to the public. The following business will be conducted: The Prince William Sound Resource...

  3. 75 FR 39910 - Prince William Sound Resource Advisory Committee; Meeting

    Science.gov (United States)

    2010-07-13

    ... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee; Meeting AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource..., Anchorage, Alaska 99503. Send written comments to Prince William Sound Resource Advisory Committee, c/o USDA...

  4. 77 FR 45331 - Prince William Sound Resource Advisory Committee

    Science.gov (United States)

    2012-07-31

    ... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... Prince William Sound Resource Advisory Committee (RAC) will be discussing and voting on proposals that...

  5. 33 CFR 110.233 - Prince William Sound, Alaska.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  6. Armstrong Flight Research Center Flight Test Capabilities and Opportunities for the Applications of Wireless Data Acquisition Systems

    Science.gov (United States)

    Hang, Richard

    2015-01-01

    The presentation will overview NASA Armstrong Flight Research Centers flight test capabilities, which can provide various means for flight testing of passive and active wireless sensor systems, also, it will address the needs of the wireless data acquisition solutions for the centers flight instrumentation issues such as additional weight caused by added instrumentation wire bundles, connectors, wire cables routing, moving components, etc., that the Passive Wireless Sensor Technology Workshop may help. The presentation shows the constraints and requirements that the wireless sensor systems will face in the flight test applications.

  7. Interview with Mark Watson

    Directory of Open Access Journals (Sweden)

    Katy Shaw

    2016-04-01

    Full Text Available Mark Watson is a British comedian and novelist. His five novels to date – 'Bullet Points' (2004, 'A Light-Hearted Look At Murder' (2007, 'Eleven' (2010, 'The Knot' (2012 and 'Hotel Alpha' (2014 – explore human relationships and communities in contemporary society. His latest novel Hotel Alpha tells the story of an extraordinary hotel in London and two mysterious disappearances that raise questions no one seems willing to answer. External to the novel, readers can also discover more about the hotel and its inhabitants in one hundred extra stories that expand the world of the novel and can be found at http://www.hotelalphastories.com. In conversation here with Dr Katy Shaw, Mark offers some reflections on his writing process, the field of contemporary literature, and the vitality of the novel form in the twenty-first century.

  8. Surface-water and ground-water quality in the Powell Creek and Armstrong Creek Watersheds, Dauphin County, Pennsylvania, July-September 2001

    Science.gov (United States)

    Galeone, Daniel G.; Low, Dennis J.

    2003-01-01

    Powell Creek and Armstrong Creek Watersheds are in Dauphin County, north of Harrisburg, Pa. The completion of the Dauphin Bypass Transportation Project in 2001 helped to alleviate traffic congestion from these watersheds to Harrisburg. However, increased development in Powell Creek and Armstrong Creek Watersheds is expected. The purpose of this study was to establish a baseline for future projects in the watersheds so that the effects of land-use changes on water quality can be documented. The Pennsylvania Department of Environmental Protection (PADEP) (2002) indicates that surface water generally is good in the 71 perennial stream miles in the watersheds. PADEP lists 11.1 stream miles within the Armstrong Creek and 3.2 stream miles within the Powell Creek Watersheds as impaired or not meeting water-quality standards. Siltation from agricultural sources and removal of vegetation along stream channels are cited by PADEP as likely factors causing this impairment.

  9. Rorty, Williams, and Davidson: Skepticism and Metaepistemology

    Directory of Open Access Journals (Sweden)

    Christopher Ranalli

    2013-07-01

    Full Text Available We revisit an important exchange on the problem of radical skepticism between Richard Rorty and Michael Williams. In his contribution to this exchange, Rorty defended the kind of transcendental approach to radical skepticism that is offered by Donald Davidson, in contrast to Williams’s Wittgenstein-inspired view. It is argued that the key to evaluating this debate is to understand the particular conception of the radical skeptical problem that is offered in influential work by Barry Stroud, a conception of the skeptical problem which generates metaepistemological ramifications for anti-skeptical theories. In particular, we argue that, contra Williams, Rorty’s view that Davidson was offering a theoretical diagnosis of radical skepticism can be consistently maintained with his transcendental approach.

  10. Revisiting Neil Armstrongs Moon-Landing Quote: Implications for Speech Perception, Function Word Reduction, and Acoustic Ambiguity.

    Directory of Open Access Journals (Sweden)

    Melissa M Baese-Berk

    Full Text Available Neil Armstrong insisted that his quote upon landing on the moon was misheard, and that he had said one small step for a man, instead of one small step for man. What he said is unclear in part because function words like a can be reduced and spectrally indistinguishable from the preceding context. Therefore, their presence can be ambiguous, and they may disappear perceptually depending on the rate of surrounding speech. Two experiments are presented examining production and perception of reduced tokens of for and for a in spontaneous speech. Experiment 1 investigates the distributions of several acoustic features of for and for a. The results suggest that the distributions of for and for a overlap substantially, both in terms of temporal and spectral characteristics. Experiment 2 examines perception of these same tokens when the context speaking rate differs. The perceptibility of the function word a varies as a function of this context speaking rate. These results demonstrate that substantial ambiguity exists in the original quote from Armstrong, and that this ambiguity may be understood through context speaking rate.

  11. Revisiting Neil Armstrongs Moon-Landing Quote: Implications for Speech Perception, Function Word Reduction, and Acoustic Ambiguity.

    Science.gov (United States)

    Baese-Berk, Melissa M; Dilley, Laura C; Schmidt, Stephanie; Morrill, Tuuli H; Pitt, Mark A

    2016-01-01

    Neil Armstrong insisted that his quote upon landing on the moon was misheard, and that he had said one small step for a man, instead of one small step for man. What he said is unclear in part because function words like a can be reduced and spectrally indistinguishable from the preceding context. Therefore, their presence can be ambiguous, and they may disappear perceptually depending on the rate of surrounding speech. Two experiments are presented examining production and perception of reduced tokens of for and for a in spontaneous speech. Experiment 1 investigates the distributions of several acoustic features of for and for a. The results suggest that the distributions of for and for a overlap substantially, both in terms of temporal and spectral characteristics. Experiment 2 examines perception of these same tokens when the context speaking rate differs. The perceptibility of the function word a varies as a function of this context speaking rate. These results demonstrate that substantial ambiguity exists in the original quote from Armstrong, and that this ambiguity may be understood through context speaking rate.

  12. Ethical Life in Kierkegaard and Williams

    OpenAIRE

    Stocker, Barry

    2018-01-01

    A discussion of how the criticisms of ethical theory in Søren Kierkegaard and Bernard Williams both reinforce each other and also provide some challenges to each other. Despite Williams’ brief and dismissive encounter with Kierkegaard around the reading of a ancient tragedy, both oppose any tendency to see the characters in those tragedies as lacking in agency. Both are consistently concerned with how the individual struggles for some ethical agency and how no individual can be free of the in...

  13. Random Thoughts on William Shakespeare and Medicine

    OpenAIRE

    KV Sahasranam

    2017-01-01

    Medicine and literature have always been connected over the ages. William Shakespeare (1564-1616) is no exception. There are plenty of references to medicine and diseases in the works of Shakespeare. The knowledge which Shakespeare has of medical conditions is much more than is expected of a common man. This is attributed to his association with practitioners of his time and reading of contemporary texts in medicine. Also his son in law Dr. John Hall who married Susanna, Shakespeare's eldest ...

  14. Learning by observation: insights from Williams syndrome.

    Science.gov (United States)

    Foti, Francesca; Menghini, Deny; Mandolesi, Laura; Federico, Francesca; Vicari, Stefano; Petrosini, Laura

    2013-01-01

    Observing another person performing a complex action accelerates the observer's acquisition of the same action and limits the time-consuming process of learning by trial and error. Observational learning makes an interesting and potentially important topic in the developmental domain, especially when disorders are considered. The implications of studies aimed at clarifying whether and how this form of learning is spared by pathology are manifold. We focused on a specific population with learning and intellectual disabilities, the individuals with Williams syndrome. The performance of twenty-eight individuals with Williams syndrome was compared with that of mental age- and gender-matched thirty-two typically developing children on tasks of learning of a visuo-motor sequence by observation or by trial and error. Regardless of the learning modality, acquiring the correct sequence involved three main phases: a detection phase, in which participants discovered the correct sequence and learned how to perform the task; an exercise phase, in which they reproduced the sequence until performance was error-free; an automatization phase, in which by repeating the error-free sequence they became accurate and speedy. Participants with Williams syndrome beneficiated of observational training (in which they observed an actor detecting the visuo-motor sequence) in the detection phase, while they performed worse than typically developing children in the exercise and automatization phases. Thus, by exploiting competencies learned by observation, individuals with Williams syndrome detected the visuo-motor sequence, putting into action the appropriate procedural strategies. Conversely, their impaired performances in the exercise phases appeared linked to impaired spatial working memory, while their deficits in automatization phases to deficits in processes increasing efficiency and speed of the response. Overall, observational experience was advantageous for acquiring competencies

  15. Learning by observation: insights from Williams syndrome.

    Directory of Open Access Journals (Sweden)

    Francesca Foti

    Full Text Available Observing another person performing a complex action accelerates the observer's acquisition of the same action and limits the time-consuming process of learning by trial and error. Observational learning makes an interesting and potentially important topic in the developmental domain, especially when disorders are considered. The implications of studies aimed at clarifying whether and how this form of learning is spared by pathology are manifold. We focused on a specific population with learning and intellectual disabilities, the individuals with Williams syndrome. The performance of twenty-eight individuals with Williams syndrome was compared with that of mental age- and gender-matched thirty-two typically developing children on tasks of learning of a visuo-motor sequence by observation or by trial and error. Regardless of the learning modality, acquiring the correct sequence involved three main phases: a detection phase, in which participants discovered the correct sequence and learned how to perform the task; an exercise phase, in which they reproduced the sequence until performance was error-free; an automatization phase, in which by repeating the error-free sequence they became accurate and speedy. Participants with Williams syndrome beneficiated of observational training (in which they observed an actor detecting the visuo-motor sequence in the detection phase, while they performed worse than typically developing children in the exercise and automatization phases. Thus, by exploiting competencies learned by observation, individuals with Williams syndrome detected the visuo-motor sequence, putting into action the appropriate procedural strategies. Conversely, their impaired performances in the exercise phases appeared linked to impaired spatial working memory, while their deficits in automatization phases to deficits in processes increasing efficiency and speed of the response. Overall, observational experience was advantageous for

  16. Congenital heart defects in Williams syndrome.

    Science.gov (United States)

    Yuan, Shi-Min

    2017-01-01

    Yuan SM. Congenital heart defects in Williams syndrome. Turk J Pediatr 2017; 59: 225-232. Williams syndrome (WS), also known as Williams-Beuren syndrome, is a rare genetic disorder involving multiple systems including the circulatory system. However, the etiologies of the associated congenital heart defects in WS patients have not been sufficiently elucidated and represent therapeutic challenges. The typical congenital heart defects in WS were supravalvar aortic stenosis, pulmonary stenosis (both valvular and peripheral), aortic coarctation and mitral valvar prolapse. The atypical cardiovascular anomalies include tetralogy of Fallot, atrial septal defects, aortic and mitral valvular insufficiencies, bicuspid aortic valves, ventricular septal defects, total anomalous pulmonary venous return, double chambered right ventricle, Ebstein anomaly and arterial anomalies. Deletion of the elastin gene on chromosome 7q11.23 leads to deficiency or abnormal deposition of elastin during cardiovascular development, thereby leading to widespread cardiovascular abnormalities in WS. In this article, the distribution, treatment and surgical outcomes of typical and atypical cardiac defects in WS are discussed.

  17. Isotopic marking and tracers

    International Nuclear Information System (INIS)

    Morel, F.

    1997-01-01

    The use of radioactive isotopes as tracers in biology has been developed thanks to the economic generation of the required isotopes in accelerators and nuclear reactors, and to the multiple applications of tracers in the life domain; the most usual isotopes employed in biology are carbon, hydrogen, phosphorus and sulfur isotopes, because these elements are present in most of organic molecules. Most of the life science knowledge appears to be dependent to the extensive use of nuclear tools and radioactive tracers; the example of the utilization of radioactive phosphorus marked ATP to study the multiple reactions with proteins, nucleic acids, etc., is given

  18. Ceremony marking Einstein Year

    CERN Multimedia

    2005-01-01

    Sunday 13th November at 10:00amat Geneva's St. Peter's Cathedral To mark Einstein Year and the importance of the intercultural dialogue of which it forms a part, a religious service will take place on Sunday 13 November at 10 a.m. in St. Peter's Cathedral, to which CERN members and colleagues are warmly welcomed. Pastor Henry Babel, senior minister at the Cathedral, will speak on the theme: 'God in Einstein's Universe'. Diether Blechschmidt will convey a message on behalf of the scientific community.

  19. Minimal Marking: A Success Story

    Science.gov (United States)

    McNeilly, Anne

    2014-01-01

    The minimal-marking project conducted in Ryerson's School of Journalism throughout 2012 and early 2013 resulted in significantly higher grammar scores in two first-year classes of minimally marked university students when compared to two traditionally marked classes. The "minimal-marking" concept (Haswell, 1983), which requires…

  20. Creating Innovative Frameworks to Spur Cultural Change at NASA Armstrong Flight Research Center

    Science.gov (United States)

    Samuel, Aamod; Lozano, Joel; Carte, Olivia; Robillos, Troy

    2018-01-01

    Changing the culture of an organization is a monumental task that often takes years and has no set formula. Steps can be taken, however, to spur cultural change by creating spaces and infrastructure to serve as the initial driving force. An innovation space and a bicycle sharing (bike share) program were implemented at the National Aeronautics and Space Administration (NASA) Armstrong Flight Research Center (AFRC) (Edwards, California) with a vision toward connecting Center personnel, fostering collaboration and innovation, retaining newer employees, promoting flexibility, and improving the culture and workplace atmosphere. This paper discusses the steps taken, challenges faced, novel culture-change-focused design elements, lessons learned, acquired metrics, and how these initiated cultural change at AFRC. For both the innovation space and the bike share program, funding was negotiated and provided through the NASA Convergent Aeronautics Solutions (CAS) project, which was seeking to improve the innovation and collaboration capabilities at each of the four NASA aeronautics Centers. Key stakeholders across AFRC from upper management, facilities, safety, engineering, and procurement were identified early in the process and were consulted and included throughout execution to ensure that any encountered roadblocks could be easily navigated. Research was then conducted by attending conferences and visiting culture-changing organizations both inside and outside United States Government agencies. Distilling the research, identifying available space, and deciding on specific design elements for the space was conducted by a subset of individuals of diverse backgrounds to enable quick, effective decision-making. Decisions were made with the intent to increase usage and diversity of users of the space; care was taken to ensure a well-crafted atmosphere that would foster the desired culture change. The allocated physical space required major structural modifications, new

  1. Neglected Aspects and Truncated Appraisals in Vocational Counseling: Interpreting the Interest-Efficacy Association from a Broader Perspective--Comment on Armstrong and Vogel (2009)

    Science.gov (United States)

    Lubinski, David

    2010-01-01

    Invited commentary on Armstrong and Vogel's (2009) article on interpreting the interest-efficacy association stimulated an appraisal from a broader perspective. Like empirical research, scale development, and theorizing emanating from social cognitive career theory (SCCT), their conclusion about the importance of assessing both interests and…

  2. The Self-Efficacy-Interest Relationship and RIASEC Type: Which Is Figure and Which Is Ground? Comment on Armstrong and Vogel (2009)

    Science.gov (United States)

    Lent, Robert W.; Sheu, Hung-Bin; Brown, Steven D.

    2010-01-01

    Armstrong and Vogel (2009) proposed that the differences between self-efficacy and interests are a matter of measurement artifact rather than substance. In tests of this hypothesis, they conceived of self-efficacy and interest as observed indicators of larger RIASEC (Realistic, Investigative, Artistic, Social, Enterprising, and Conventional) types…

  3. TENNESSEE WILLIAMS E O TEATRO MARGINAL GAY

    Directory of Open Access Journals (Sweden)

    Adriana Falqueto Lemos

    2014-06-01

    Full Text Available The work developed in this text aims to read the dramatist Tennnessee Williams in a play in two scenes “E Contar Tristes Histórias das Mortes das Bonecas” which was published in Brazil in the book “Mister Paradise e outras peças em um ato” (2011. The intention is to reflect upon one of his recurring themes, the marginalization. In order to perform the analysis, the theoretical support was grounded in “Literatura e Sociedade” by Antonio Candido (2006, concerning the participation of society and authorship in a piece of literature.

  4. TENNESSEE WILLIAMS E O TEATRO MARGINAL GAY

    Directory of Open Access Journals (Sweden)

    Adriana Falqueto Lemos

    2014-09-01

    Full Text Available The work developed in this text aims to read the dramatist Tennnessee Williams in a play in two scenes “E Contar Tristes Histórias das Mortes das Bonecas” which was published in Brazil in the book “Mister Paradise e outras peças em um ato” (2011. The intention is to reflect upon one of his recurring themes, the marginalization. In order to perform the analysis, the theoretical support was grounded in “Literatura e Sociedade” by Antonio Candido (2006, concerning the participation of society and authorship in a piece of literature.

  5. WILLIAM HAZLITT, OBSESSIVE LOVE, AND LIBER AMORIS.

    Science.gov (United States)

    Trosman, Harry

    2017-07-01

    William Hazlitt, a distinguished literary figure of the early nineteenth century and a forerunner of psychoanalytic insights, had a keen awareness of the impact of the imagination on assessing works of art. At forty-two, he became hopelessly involved in an obsessive love affair with a nineteen-year-old woman and could not extricate himself from the relationship. The affair followed the death of his father, a powerful influence on his life. Factors in his obsessive love included finding an object of idealization subject to his imaginative creation and narcissistically reexperiencing himself about to begin a new life. © 2017 The Psychoanalytic Quarterly, Inc.

  6. Enough room for Williams and IMF? / Paul Beckman

    Index Scriptorium Estoniae

    Beckman, Paul

    1999-01-01

    Lõppesid Leedu ja USA energeetikakompanii Williams International läbirääkimised Leedu naftakompleksis osaluse omandamise asjus. IMF uurib Leedu majanduslikku arengut, mida tehing Williamsiga komplitseerib

  7. Social organization of sea otters in Prince William Sound, Alaska

    Science.gov (United States)

    Garshelis, David L.; Johnson, Ancel M.; Garshelis, Judith A.

    1984-01-01

    Sea otters in Prince William Sound. Alaska, were spatially segregated into predominantly (97%) male areas at the front of the expanding population and breeding areas with fewer (up to 33%) males. From 1975 to 1984 we captured and marked 267 otters with tags and (or) radio transmitters and investigated their reproductive strategies, social relationships, and patterns of sexual segregation. Mating occurred year-round, but peaked in September and October. Females first bred at 4 years of age and were capable of pupping annually; they generally separated from their pup before mating. Males established breeding territories that enabled prolonged precopulatory interactions that may have prompted female–pup separation and post-copulatory interactions that precluded females from mating with other males. Male mating success was related to age, weight, territory quality, and the length of time they maintained their territory. After the breeding season, territorial males returned to male areas where food was more abundant. Young, dispersing males also entered male areas and remained there until attaining breeding age. In male areas, otters commonly rested in groups of >50 individuals. Gregariousness promoted social interactions and likely enhanced food finding and (historically) predator protection. As food diminished, males moved into adjacent, unoccupied regions; females then occupied former male areas.

  8. Sir William Petty: modern epidemiologist (1623-1687).

    Science.gov (United States)

    Banta, J E

    1987-01-01

    William Petty, physician, epidemiologist, political economist, demographer, cartographer, and administrator was an intellectual product of the seventeenth century. Petty was born in the year 1623 in Romsey, England of lower middle class parents; however, by the time of his death in 1687 he had become a knight of the realm, founder of the Royal Society, and friend of kings. Petty's life reflected the northern renaissance which induced such dramatic changes in science, technology, politics, and entrepreneurship. His education was eclectic, nonetheless he took his Doctor of Physic degree from Oxford in 1649 and became an Oxford don, where he spent the next few years as an academic before undertaking a definitive survey of Ireland on behalf of the Cromwell government. Ireland changed Petty's destiny and he became a man of the world and entrepreneur which stimulated his interest in public policy formulation and economics. It was Petty's peculiar genius to be innovative in the application of measurement, statistics, and mathematics to socioeconomic and demographic phenomena. As a physician he related his knowledge of health and disease to these phenomena in what in the modern context would be called human ecology or social epidemiology. These relationships and their measurement were employed to establish an objective set of data which could be analyzed for the purpose of rational public policy planning by the state. This scientific approach to public policy places Petty squarely in the context of modern epidemiologic and public health practice and marks the initiation of a major use of the epidemiologic method.

  9. Morphological differences in the mirror neuron system in Williams syndrome.

    Science.gov (United States)

    Ng, Rowena; Brown, Timothy T; Erhart, Matthew; Järvinen, Anna M; Korenberg, Julie R; Bellugi, Ursula; Halgren, Eric

    2016-01-01

    Williams syndrome (WS) is a genetic condition characterized by an overly gregarious personality, including high empathetic concern for others. Although seemingly disparate from the profile of autism spectrum disorder (ASD), both are associated with deficits in social communication/cognition. Notably, the mirror neuron system (MNS) has been implicated in social dysfunction for ASD; yet, the integrity of this network and its association with social functioning in WS remains unknown. Magnetic resonance imaging (MRI) methods were used to examine the structural integrity of the MNS of adults with WS versus typically developing (TD) individuals. The Social Responsiveness Scale (SRS), a tool typically used to screen for social features of ASD, was also employed to assess the relationships between social functioning with the MNS morphology in WS participants. WS individuals showed reduced cortical surface area of MNS substrates yet relatively preserved cortical thickness as compared to TD adults. Increased cortical thickness of the inferior parietal lobule (IPL) was associated with increased deficits in social communication, social awareness, social cognition, and autistic mannerisms. However, social motivation was not related to anatomical features of the MNS. Our findings indicate that social deficits typical to both ASD and WS may be attributed to an aberrant MNS, whereas the unusual social drive marked in WS is subserved by substrates distinct from this network.

  10. An improved Armstrong-Frederick-Type Plasticity Model for Stable Cyclic Stress-Strain Responses Considering Nonproportional Hardening

    Science.gov (United States)

    Li, Jing; Zhang, Zhong-ping; Li, Chun-wang

    2018-03-01

    This paper modified an Armstrong-Frederick-type plasticity model for investigating the stable cyclic deformation behavior of metallic materials with different sensitivity to nonproportional loadings. In the modified model, the nonproportionality factor and nonproportional cyclic hardening coefficient coupled with the Jiang-Sehitoglu incremental plasticity model were used to estimate the stable stress-strain responses of the two materials (1045HR steel and 304 stainless steel) under various tension-torsion strain paths. A new equation was proposed to calculate the nonproportionality factor on the basis of the minimum normal strain range. Procedures to determine the minimum normal strain range were presented for general multiaxial loadings. Then, the modified model requires only the cyclic strain hardening exponent and cyclic strength coefficient to determine the material constants. It is convenient for predicting the stable stress-strain responses of materials in engineering application. Comparisons showed that the modified model can reflect the effect of nonproportional cyclic hardening well.

  11. William Butler Yeats’s ‘The Symbolic System’ of William Blake

    Directory of Open Access Journals (Sweden)

    Arianna Antonielli

    2008-03-01

    Full Text Available The theosophical systems formulated by great poets, such as William Blake and William Butler Yeats, represent a personal idiosyncratic actualization of an ancient repertoire of magical symbols and occult visions. This study wants to focus the attention on the philosophical, mythical, and esoteric syncretism that W. B. Yeats drew from William Blake’s symbolical system. A fundamental step of Yeats’s deep investigation into the Blakean ‘vision’ was given by his monumental work, written together with Edwin John Ellis, on Blake’s poetic and pictorial production, completed in 1893 with a three-volume edition entitled The Works of William Blake, Poetic, Symbolic, and Critical. This work, published in London by Bernard Quaritch, deeply influenced Yeats’s symbolical and imaginary system, determining its subsequent development up to its codification in the volume of A Vision. With WWB, Yeats was able to systematize for the first time his own thought, giving unity to his Weltanschauung and his poetry. Following this hypothesis, I concentrated on Yeats’s and Ellis’s numerous analyses dedicated to Blake’s mythological and symbolical corpus and, in particular, I examined the last chapter of the first volume of the Quaritch edition. This chapter, entitled “The Symbolic System”, constitutes an unquestionable link between Yeats the reader and scholar of Blake, and Yeats the poet and follower of Blake.

  12. The spatial distribution of errors made by rats in Hebb-Williams type mazes in relation to the spatial properties of the blind alleys

    NARCIS (Netherlands)

    Boer, S. de; Bohus, B.

    The various configurations in series of Hebb-Williams type of mazes, which are used to measure problem solving behaviour in rats, differ markedly in structure. The relationship between error behaviour and spatial maze structure in control rats tested in a number of pharmacological experiments is

  13. SLARette Mark 2 system

    International Nuclear Information System (INIS)

    Burnett, D.J.

    1992-01-01

    The SLAR (Spacer Location and Repositioning) program has developed the technology and tooling necessary to locate and reposition the fuel channel spacers that separate the pressure tube from the calandria tube in a CANDU reactor. The in-channel SLAR tool contains all the inspection probes, and is capable of moving spacers under remote control. The SLAR inspection computer system translates all eddy currents and ultrasonic signals from the in-channel tool into various graphic displays. The in-channel SLAR tool can be delivered and manipulated in a fuel channel by either a SLAR delivery machine or a SLARette delivery machine. The SLAR delivery machine consists of a modified fuelling machine, and is capable of operating under totally remote control in automatic or semi-automatic mode. The SLARette delivery machine is a smaller less automated version, which was designed to be quickly installed, operated, and removed from a limited number of fuel channels during regular annual maintenance outages. This paper describes the design and operation of the SLARette Mark 2 system. 5 figs

  14. The scientific legacy of William Herschel

    CERN Document Server

    2018-01-01

    This book presents a modern scholarly analysis of issues associated with England’s most famous astronomer, William Herschel. The world’s leading experts on Herschel, discoverer of the planet Uranus, here offer their combined wisdom on many aspects of his life and astronomical research. Solar system topics include comets, Earth’s Moon, and the spurious moons of Uranus, all objects whose observation was pioneered by Herschel.  The contributors examine his study of the structure of the Milky Way and an in-depth look at the development of the front view telescopes he built. The popular subject of extraterrestrial life is looked at from the point of view of both William Herschel and his son John, both of whom had an interest in the topic. William’s personal development through the educational system of the late eighteenth-century is also explored, and the wide range of verse and satire in various languages associated with his discoveries is collected here for the first time. Hershel worked at a time of i...

  15. Colour discrimination and categorisation in Williams syndrome.

    Science.gov (United States)

    Farran, Emily K; Cranwell, Matthew B; Alvarez, James; Franklin, Anna

    2013-10-01

    Individuals with Williams syndrome (WS) present with impaired functioning of the dorsal visual stream relative to the ventral visual stream. As such, little attention has been given to ventral stream functions in WS. We investigated colour processing, a predominantly ventral stream function, for the first time in nineteen individuals with Williams syndrome. Colour discrimination was assessed using the Farnsworth-Munsell 100 hue test. Colour categorisation was assessed using a match-to-sample test and a colour naming task. A visual search task was also included as a measure of sensitivity to the size of perceptual colour difference. Results showed that individuals with WS have reduced colour discrimination relative to typically developing participants matched for chronological age; performance was commensurate with a typically developing group matched for non-verbal ability. In contrast, categorisation was typical in WS, although there was some evidence that sensitivity to the size of perceptual colour differences was reduced in this group. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. 76 FR 44893 - Prince William Sound Resource Advisory Committee

    Science.gov (United States)

    2011-07-27

    ... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... District, 145 Forest Station Road, Girdwood, AK; Prince Willam Sound Community College, 303 Lowe Street...

  17. The William and Flora Hewlett Foundation | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The William and Flora Hewlett Foundation. The William and Flora Hewlett Foundation. http://www.hewlett.org/. Think Tank Initiative. This initiative is creating high-quality independent research and policy institutions throughout the developing world. View more. Think Tank Initiative. Growth and Economic Opportunities for ...

  18. 78 FR 28953 - William D. Ford Federal Direct Loan Program

    Science.gov (United States)

    2013-05-16

    .... Ford Federal Direct Loan Program; Interim Final Rule #0;#0;Federal Register / Vol. 78, No. 95... [Docket ID ED-2013-OPE-0066] RIN 1840-AD13 William D. Ford Federal Direct Loan Program AGENCY: Office of... Secretary amends the William D. Ford Federal Direct Loan Program (Direct Loan Program) regulations to...

  19. Handedness and corpus callosal morphology in Williams syndrome.

    Science.gov (United States)

    Martens, Marilee A; Wilson, Sarah J; Chen, Jian; Wood, Amanda G; Reutens, David C

    2013-02-01

    Williams syndrome is a neurodevelopmental genetic disorder caused by a hemizygous deletion on chromosome 7q11.23, resulting in atypical brain structure and function, including abnormal morphology of the corpus callosum. An influence of handedness on the size of the corpus callosum has been observed in studies of typical individuals, but handedness has not been taken into account in studies of callosal morphology in Williams syndrome. We hypothesized that callosal area is smaller and the size of the splenium and isthmus is reduced in individuals with Williams syndrome compared to healthy controls, and examined age, sex, and handedness effects on corpus callosal area. Structural magnetic resonance imaging scans were obtained on 25 individuals with Williams syndrome (18 right-handed, 7 left-handed) and 25 matched controls. We found that callosal thickness was significantly reduced in the splenium of Williams syndrome individuals compared to controls. We also found novel evidence that the callosal area was smaller in left-handed participants with Williams syndrome than their right-handed counterparts, with opposite findings observed in the control group. This novel finding may be associated with LIM-kinase hemizygosity, a characteristic of Williams syndrome. The findings may have significant clinical implications in future explorations of the Williams syndrome cognitive phenotype.

  20. Mental Health Problems in Adults with Williams Syndrome

    Science.gov (United States)

    Stinton, Chris; Elison, Sarah; Howlin, Patricia

    2010-01-01

    Although many researchers have investigated emotional and behavioral difficulties in individuals with Williams syndrome, few have used standardized diagnostic assessments. We examined mental health problems in 92 adults with Williams syndrome using the Psychiatric Assessment Schedule for Adults with Developmental Disabilities--PAS-ADD (Moss,…

  1. Emotional Responsivity in Young Children with Williams Syndrome

    Science.gov (United States)

    Fidler, Debbie J.; Hepburn, Susan L.; Most, David E.; Philofsky, Amy; Rogers, Sally J.

    2007-01-01

    The hypothesis that young children with Williams syndrome show higher rates of emotional responsivity relative to other children with developmental disabilities was explored. Performance of 23 young children with Williams syndrome and 30 MA-matched children with developmental disabilities of nonspecific etiologies was compared on an adaptation of…

  2. Discovering Structure in Auditory Input: Evidence from Williams Syndrome

    Science.gov (United States)

    Elsabbagh, Mayada; Cohen, Henri; Karmiloff-Smith, Annette

    2010-01-01

    We examined auditory perception in Williams syndrome by investigating strategies used in organizing sound patterns into coherent units. In Experiment 1, we investigated the streaming of sound sequences into perceptual units, on the basis of pitch cues, in a group of children and adults with Williams syndrome compared to typical controls. We showed…

  3. Mailability v. the Crusader: Williams v. O'Brien.

    Science.gov (United States)

    Simmons, Charles E.

    The issues of prior restraint and press censorship are examined in this paper, which focuses on the 1970 Williams v. O'Brien court case. The paper discusses the litigation, in which Robert F. Williams, as an American citizen living in Peking, China, sued the United States Postmaster General over the banning of the May 1967 issue of "The…

  4. Malformations vasculaires au cours du syndrome de Williams ...

    African Journals Online (AJOL)

    Le syndrome de Williams-Beuren est une maladie génétique rare, il associe classiquement une dysmorphie faciale assez spécifique, des malformations cardiovasculaires et un profil neuropsychologique particulier. Nous rapportons les observations de trois enfants atteints du syndrome de Williams-Beuren en insistant ...

  5. Mark Kostabi soovib muuta inimesi õnnelikumaks / Kalev Mark Kostabi

    Index Scriptorium Estoniae

    Kostabi, Kalev Mark, 1960-

    2008-01-01

    Kalev Mark Kostabi oma sisekujunduslikest eelistustest, ameeriklaste ja itaallaste kodude sisekujunduse erinevustest, kunstist kui ruumikujunduse ühest osast, oma New Yorgi ja Rooma korterite kujundusest

  6. Robert Williams Wood: pioneer of invisible light.

    Science.gov (United States)

    Sharma, Shruti; Sharma, Amit

    2016-03-01

    The Wood's lamp aids in the diagnosis of multiple infectious, inflammatory and neoplastic dermatologic conditions. Although the Wood's lamp has many applications, which have improved both the diagnosis and management of disease, the man credited for its invention is relatively unknown in medicine. Robert Williams Wood, a prominent physicist of the early 20th century, is credited for the invention of the Wood's lamp. Wood was the father of infrared and ultraviolet photography and made significant contributions to other areas in optics and spectroscopy. Wood's work encompassed the formative years of American Physics; he published over 200 original papers over his lifetime. A few years after the invention of the Wood's lamp for ultraviolet photography, physicians in Europe adopted the Wood's lamp for dermatologic applications. Wood's lamp remains popular in clinics globally, given its ease of use and ability to improve diagnostic precision. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. A Mystic in English Literature: William Blake

    Directory of Open Access Journals (Sweden)

    Ali Fahri DOĞAN

    2015-12-01

    Full Text Available Human beings have never been satisfied with this ephemeral world. Perhaps, yearning and desire of rejoining −stemming from the descent from the heaven to the earth− are the emotions felt by the members of both celestial and non-celestial religions. Mysticism, having started with the zeal of people who weren‘t satisfied with this ephemeral world towards the eternal world, aimed at the love of God in the religions where there is a belief of single God. In this article, glancing at the life of a Christian mystic William Blake, we will try to shed light into his mystic thoughts. While studying Blake‘s mystic thoughts, there will be common points with Sufism. Nevertheless, analysis of these common points has been assigned to other studies.

  8. Random Thoughts on William Shakespeare and Medicine

    Directory of Open Access Journals (Sweden)

    KV Sahasranam

    2017-04-01

    Full Text Available Medicine and literature have always been connected over the ages. William Shakespeare (1564-1616 is no exception. There are plenty of references to medicine and diseases in the works of Shakespeare. The knowledge which Shakespeare has of medical conditions is much more than is expected of a common man. This is attributed to his association with practitioners of his time and reading of contemporary texts in medicine. Also his son in law Dr. John Hall who married Susanna, Shakespeare's eldest daughter would have contributed substantially to the knowledge of medicine in Shakespeare's compositions. Surgery at the Elizabethan times was well known and is reflected to a large extent in his plays.

  9. William Osler's "The Nervousness of American Women".

    Science.gov (United States)

    Golden, Richard L

    2008-02-01

    Almost a century ago, William Osler, the foremost physician of his time, was approached by a leading periodical to write a series of articles on the health of the American woman. Osler, then the Regius Professor of Medicine at Oxford, wrote an essay dealing with the psychological stresses affecting the "new woman" of the early 20th century at varying stages of her development and the "nervousness" that ensued. The article was never published as a result of his belated reservations on the propriety of a professional writing for a lay journal. Osler's thinking frequently reflected the spirit of his Victorian-Edwardian era, although at times he demonstrated advanced and prescient ideas about sexuality, not often the subject of discussion, even in circumspect form, in contemporary nonprofessional literature.

  10. [William W. Cadbury and canton hospital].

    Science.gov (United States)

    Liu, Ze-Sheng; Liu, Ze-En

    2004-01-01

    William W. Cadbury M.D. was born in Philadelphia, USA and graduated from the Medical College of Pennsylvania University. It was nearly 40 years since he arrived in Canton (Guangzhou) in 1909 and left at retirement age. He taught western medicine in Canton Christian College and worked as a medical doctor in Canton Hospital, the oldest western medical hospital in the Orient. He was regarded as a famous foreign doctor and an excellent professor in internal medicine in the Republic of China. He wrote At the point of Lancet: 100 years of Canton Hospital 1835 - 1935, which recorded the achievement made by American missionary doctors, particularly the pioneers such as Peter Parker M.D. and John G. Kerr. M.D. So far the book is still an important reference for the studies on history of western medicine in China and the history of modern medical exchange between China and other countries.

  11. William Crabtree and the date of Easter

    Science.gov (United States)

    Sellers, D.

    2014-04-01

    A previously unknown treatise by William Crabtree (c.1603-c.1644) has recently been unearthed in the Lancashire Record Office. The treatise, in manuscript form and written in 1640, deals with the controversy over the long-term impact of the Julian Calendar - then in use in England - upon the ecclesiastical dating of Easter. By Crabtree's time, the timing of the Easter celebration in England was often several weeks adrift of the intentions of the early Church Fathers. The Gregorian Calendar, which Roman Catholic countries had adopted as long ago as 1582 in order to resolve the problem, was still vehemently resisted by the English state. This is possibly the only surviving manuscript in Crabtree's own hand. In it, he displays noteworthy dispassionate objectivity as he outlines the astronomical basis for the Easter date and explains why it has gone awry.

  12. NotaMark industrial laser marking system: a new security marking technology

    Science.gov (United States)

    Moreau, Vincent G.

    2004-06-01

    Up until now, the only variable alphanumeric data which could be added to banknotes was the number, applied by means of impact typographical numbering boxes. As an additional process or an alternative to this mechanical method, a non-contact laser marking process can be used offering high quality and greater levels of flexibility. For this purpose KBA-GIORI propose an exclusive laser marking solution called NotaMark. The laser marking process NotaMark is the ideal solution for applying variable data and personalizing banknotes (or any other security documents) with a very high resolution, for extremely large production volumes. A completely integrated solution has been developed comprised of laser light sources, marking head units, and covers and extraction systems. NotaMark allows the marking of variable data by removing locally and selectively, specific printed materials leaving the substrate itself untouched. A wide range of materials has already been tested extensively. NotaMark is a new security feature which is easy to identify and difficult to counterfeit, and which complies with the standard mechanical and chemical resistance tests in the security printing industry as well as with other major soiling tests. The laser marking process opens up a whole new range of design possibilities and can be used to create a primary security feature such as numbering, or to enhance the value of existing features.

  13. Comment on 'Magnetosheath burst of predominantly medium nuclei observed with Imp 8 on February 16, 1974' by T. P. Armstrong, S. M. Krimigis, and R. P. Lepping

    International Nuclear Information System (INIS)

    Hovestadt, D.

    1980-01-01

    Armstrong et al. (1978) report the observation of a unique series of charged particle bursts with an unusually high content of Z>2 particles and a high degree of collimation from the direction of the sun. These bursts were observed only with their CPME (charged particle measurement experiment) instrument on Imp 8, while not with the CPME on Imp 7. No indication has been seen for heavy ion bursts comparable in intensity to those reported by Armstrong et al. (1978) with the ULET (ultralow energy telescope) instrument of the University of Maryland/Max-Planck-Institut experiment on Imp 8 at the same time. It is noted that the ULET counting rates observed on Imp 8 are fully compatible with the CPME rates observed on the Imp 7 spacecraft. We conclude that the CPME and the ULET data from IMP 8 during these periods do not agree, and this casts doubt on the correctness of the CPME results for these special events

  14. Discoverers of the universe William and Caroline Herschel

    CERN Document Server

    Hoskin, Michael

    2011-01-01

    Discoverers of the Universe tells the gripping story of William Herschel, the brilliant, fiercely ambitious, emotionally complex musician and composer who became court astronomer to Britain's King George III, and of William's sister, Caroline, who assisted him in his observations of the night sky and became an accomplished astronomer in her own right. Together, they transformed our view of the universe from the unchanging, mechanical creation of Newton's clockmaker god to the ever-evolving, incredibly dynamic cosmos that it truly is. William was in his forties when his amateur observations usi

  15. A case of William's syndrome associated peripheral pulmonary arterial stenosis

    International Nuclear Information System (INIS)

    Jung, Kyung Hwa; Hwang, Mi Soo; Kim, Sun Yong; Chang, Jae Chun; Park, Bok Hwan

    1988-01-01

    William's syndrome, in order to more completely delineate the total spectrum of the disorder, indicates that 'infantile hypercalcemia', 'peculiar facies' and 'supravalvular aortic stenosis.' In has other many vascular anomalies, such as peripheral pulmonary arterial stenosis, coronary arterial stenosis, celiac arterial stenosis, and renal aterial stenosis. Only 32% of the patients have evidence of supravalvular aortic stenosis. And it is very rare disease entity that has been reported rarely in Korea. Recently authors experienced a case that was questioned William's syndrome with peripheral pulmonary arterial stenosis, clinically and preliminary radiologically and this case was confirmed by operation. Here we report a case of William's syndrome with peripheral pulmonary arterial stenosis and reviewed literatures

  16. William L. Donn 1918-1987

    Science.gov (United States)

    Gedzelman, Stanley David

    William L. Donn, Professor Emeritus of the Department of Earth and Planetary Sciences, City College of New York, and Special Research Scientist at Lamont-Doherty Geological Observatory (LDGO) of Columbia University (Palisades, N.Y.), died at his home on June 30, 1987, at the age of 69. Bill demonstrated expertise in a wide range of fields, with a highly productive and creative research and writing career that included geology, oceanography, climatology, atmospheric physics, and meteorology.Donn was born in Brooklyn, N.Y., on March 2, 1918. At the tender age of 10 years, he demonstrated his love and talent for science by building a telescope with his brother, Bertram. During his undergraduate years at Brooklyn College, he switched his major from astronomy to geology. He was largely selftrained in both meteorology and oceanography, serving as head of the Meteorology Section, U.S. Merchant Marine Academy during World War II . One by-product of these years was the textbook Meteorology—With Marine Applications, first published in 1946. This widely adopted text became a standard for a generation of mariners and college students.

  17. Neurocranial morphology and growth in Williams syndrome.

    Science.gov (United States)

    Axelsson, Stefan; Kjaer, Inger; Heiberg, Arvid; Bjørnland, Tore; Storhaug, Kari

    2005-02-01

    Williams syndrome (WS) is a rare congenital neurodevelopmental disorder with distinctive facial features, cardiovascular abnormalities, short stature, mental retardation, and behaviour and cognitive characteristics. The aim of this study was to describe the neurocranial morphology and growth in a group of 62 individuals with WS. The neurocranium was analysed on lateral cephalograms and comparisons were made with neurocranial standards from longitudinal data derived from the Oslo University Craniofacial Growth Archive. The size and morphology of the neurocranium in WS subjects differed from controls. Females as a group showed greater differences than males. The posterior cranial base length was shorter in both WS males and females, and the anterior cranial base length was shorter in WS females whereas it was close to normal in the WS male group. The cranial base angle was, however, not different from the control groups. A flattening was seen in the superior aspect of the parietal bone in both WS males and females. In the posterior part of the neurocranium, the prominence of the occipital bone was larger than in the control groups, which was also reflected in a larger total length of the neurocranium. The thickness of the frontal and occipital bones was considerably greater than in the control group. The deviant size and morphology of the neurocranium in WS subjects was already established in the youngest age group and maintained throughout the observation period. The growth pattern of the neurocranium in WS subjects seemed to be similar to that of the control groups, except in a few individuals.

  18. Imaging of cardiovascular malformations in Williams syndrome

    International Nuclear Information System (INIS)

    Li Shiguo; Zhao Shihua; Jiang Shiliang; Huang Lianjun; Xu Zhongying; Ling Jian; Zheng Hong; Yan Chaowu; Lu Jinguo

    2008-01-01

    Objective: To evaluate the imaging methods for cardiovascular malformations in Williams syndrome(WS). Methods: Thirteen cases of WS (7 males and 6 females) aged 10 months to 13 years were involved in this study. All patients underwent chest X-ray radiography, electrocardiography, echocardiography and physical examination. 3 cases underwent electronic beam computed tomography (EBCT), cardiac catheterization and angiography were performed in 8 cases. Results: Twelve patients were referred to our hospital for cardiac murmur and 1 case for cyanosis after birth. 7 patients were found with 'elfin-like' facial features, 6 patients with pulmonary arterial stenosis, 2 cases with patent ductus arteriosus, 2 cases with severe pulmonary hypertension and 1 case with total endocardial cushion defect. Sudden death occurred in 2 patients during and after catheterization, respectively. Conclusions: Conventional angiography is the golden standard for the diagnosis of cardiovascular malformations in WS. Noninvasive methods such as MSCT and MRI should be suggested because of the risk of sudden death in conventional angiography. (authors)

  19. Sir William Mitchell (1925-2002)

    CERN Multimedia

    2002-01-01

    Sir William (Bill) Mitchell, former President of the CERN Council, died on 30th October 2002 at the age of 77. Mitchell was professor of Physics at Oxford University from 1978 to 1989, having previously been Professor of Physics, Dean of Science and Deputy Vice-Chancellor at Reading University. From 1985 to 1990 he was Chairman of the UK's Science and Engineering Research Council (SERC), which at the time was the funding agency for the UK's participation in the CERN programme. As Chairman, Mitchell was one of the UK representatives on the CERN Council, and in 1991 he was elected President, a position he held for three years. This was a difficult period for CERN. Financial problems were being faced in many member states, notably in Germany as a result of unification. This led to calls for reductions in the CERN budget and, more significantly, to requests for delays in consderation of future programmes. On the other hand for the future of CERN and the progress of elementary particle physics, it was necessary...

  20. National uranium resource evaluation: Williams quadrangle, Arizona

    International Nuclear Information System (INIS)

    O'Neill, A.J.; Nystrom, R.J.; Thiede, D.S.

    1981-03-01

    Geologic environments of the Williams Quadrangle, Arizona, were evaluated for uranium favorability by means of literature research, uranium-occurrence investigation and other surface studies, subsurface studies, aerial radiometric data, hydrogeochemical data, and rock-sample analytic data. Favorability criteria are those of the National Uranium Resource Evaluation program. Three geologic environments are favorable for uranium: the Tertiary fluvial rocks of the Colorado Plateau where they unconformably overlie impermeable bed rock (for channel-controlled peneconcordant deposits); collapse breccia pipes in Paleozoic strata of the Colorado Plateau (for vein-type deposits in sedimentary rocks); and Precambrian crystalline rocks of the Hualapai, Peacock, and Aquarius Mountains, and Cottonwood and Grand Wash Cliffs (for magmatic-hydrothermal deposits). Unfavorable geologic environments are: Tertiary and Quaternary volcanic rocks, Tertiary and Quaternary sedimentary rocks of the Colorado Plateau, nearly all Paleozoic and Mesozoic sedimentary rocks, and the Precambrian-Cambrian unconformity of the Grand Wash Cliffs area. Tertiary rocks in Cenozoic basins and Precambrian crystalline rocks in the Grand Canyon region and in parts of the Aquarius Mountains and Cottonwood and Grand Wash Cliffs are unevaluated

  1. Space perception and William James's metaphysical presuppositions.

    Science.gov (United States)

    Farrell, Martin J

    2011-05-01

    William James's overtly philosophical work may be more continuous with his psychological work than is sometimes thought. His Essays in Radical Empiricism can be understood as an explicit statement of the absolute presupposition that formed the basis of Jamesian psychology: that direct experience is primary and has to be taken at face value. An examination of James's theory of space perception suggests that, even in his early work, he presupposed the primacy of direct experience, and that later changes in his account of space perception can be understood as making his view more consistent with this presupposition. In his earlier view of space perception, James argued that sensations were directly experienced as spatial, though he accepted that spatial relations between sensations may be constructed by higher order thought. In his later view, however, James argued that spatial relations were just as directly experienced as sensations. The work of T. H. Green may have prompted James to recognize the full consequence of his ideas and to realize that taking experience at face value required that spatial relations be thought of as intrinsic to experience rather than the result of intellectual construction.

  2. William James and the Heidelberg fiasco.

    Science.gov (United States)

    Gundlach, Horst

    2018-02-01

    Urged on by his father to become a physician instead of a painter, William James pursued 3 evasion stratagems. First, to avoid becoming a practitioner, he declared that he wanted to specialize in physiology. Based upon this premise, he left for Germany in the spring of 1867. The second step was giving up general physiology and announcing that he would specialize in the nervous system and psychology. Based upon this premise, he declared that he would go to Heidelberg and study with Helmholtz and Wundt. However, he then deferred going there. When, at last, he was urged by an influential friend of his father's to accompany him to Heidelberg, he employed his default stratagem: He simply fled. He returned home after 3 terms in Europe without enrolling at a single university. There is no evidence that he had learned anything there about psychology or experimental psychology, except, possibly, by reading books. James's "Heidelberg fiasco" was the apogee of his evasion of his father's directive. A dense fog of misinformation surrounds his stay in Heidelberg to this day. By analyzing circumstances and context, this article examines the fiasco and places it in the pattern of his behavior during his stay in Europe. Nevertheless, experiencing this fiasco potentially shaped James's ambivalent attitude toward experimental psychology on a long-term basis. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  3. Ending Caleb Williams: on storytelling influencing William Godwin’s politics

    Directory of Open Access Journals (Sweden)

    Peterson Roberto da Silva

    2017-12-01

    Full Text Available William Godwin escreveu o romance gótico Things as They Are; or, the Adventures of Caleb Williams (“As Coisas como Elas São; ou, as Aventuras de Caleb Williams”, em tradução livre em 1794 para disseminar suas ideias filosóficas e políticas. Inicio o artigo revisando a literatura para demonstrar como sua teoria influenciou tanto sua decisão de escrever ficções quanto o tipo de ficção que ele escreveu, mostrando como o autor usou e inovou convenções do gênero gótico para transmitir suas ideias para um público mais amplo. Então comparo duas perspectivas divergentes na literatura quanto à maneira como suas narrativas influenciaram suas ideias políticas e filosóficas, em particular a partir de comentários acerca do significado e do impacto de mudanças de última hora ao desfecho de Caleb Williams. Argumento que essa relação ambígua entre narrativa e política na obra de Godwin é relevante para reflexões políticas contemporâneas sobre a relação entre representação e ação política, ou como narrativas sobre a condição humana e realidades políticas podem afetas as ideias, atitudes e relações sociais de seus narradores.

  4. Global and local music perception in children with Williams syndrome.

    Science.gov (United States)

    Deruelle, Christine; Schön, Daniele; Rondan, Cécilie; Mancini, Josette

    2005-04-25

    Musical processing can be decomposed into the appreciation of global and local elements. This global/local dissociation was investigated with the processing of contour-violated and interval-violated melodies. Performance of a group of 16 children with Williams syndrome and a group of 16 control children were compared in a same-different task. Control participants were more accurate in detecting differences in the contour-violated than in the interval-violated condition while Williams syndrome individuals performed equally well in both conditions. This finding suggests that global precedence may occur at an early perceptual stage in normally developing children. In contrast, no such global precedence is observed in the Williams syndrome population. These data are discussed in the context of atypical cognitive profiles of individuals with Williams syndrome.

  5. Comparison of the acute effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    William Henry Harvey (Alliaceae) on blood pressure and heart rate of ... (WKY), and compare the results obtained with those for adult spontaneously hypertensive rats (SHR). Methods: T. ... have similar secondary metabolites and biological ...

  6. Herbert Hoover and William Shakespeare: Two Writers on Ethics.

    Science.gov (United States)

    Somers, Margaret L.

    1979-01-01

    Outlines the ways in which Herbert Hoover and William Shakespeare wrote about professional ethics (for engineers and kings, respectively) using the writing techniques of concreteness, audience awareness, and development by induction. (TJ)

  7. Dental management of patient with Williams Syndrome - A case report.

    Science.gov (United States)

    Wong, Daniel; Ramachandra, Srinivas Sulugodu; Singh, Ashish Kumar

    2015-01-01

    Williams syndrome is a multisystemic rare genetic disorder caused by deletion of 26-28 genes in the long arm of chromosome 7. It is characterized by developmental and physical abnormalities including congenital cardiovascular abnormalities, mental retardation, neurological features, growth deficiency, genitourinary manifestations, gastrointestinal problems, musculoskeletal problems, unique behavioral characteristics, and dental problems. Dental abnormalities include malocclusion, hypodontia, malformed teeth, taurodontism, pulp stones, increased space between teeth, enamel hypoplasia, and high prevalence of dental caries. Authors report a 17-year-old female patient with underlying Williams syndrome. Oral features and problems seen in the patient are listed. Malocclusion and screwdriver shaped teeth were noticed. Generalized widening of the periodontal ligament space with vital teeth was seen. This finding has not been reported in cases of Williams syndrome earlier. Precautions taken during dental treatment in patients with Williams syndrome are also discussed.

  8. Prince William Sound, Alaska ESI: NESTS (Bird Nests)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  9. Prince William Sound, Alaska ESI: FISH (Fish Polygons)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  10. 34 CFR 685.100 - The William D. Ford Federal Direct Loan Program.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false The William D. Ford Federal Direct Loan Program. 685...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION WILLIAM D. FORD FEDERAL DIRECT LOAN PROGRAM Purpose and Scope § 685.100 The William D. Ford Federal Direct Loan Program. (a) Under the William D. Ford...

  11. William Fowler and Elements in the Stars

    Science.gov (United States)

    with the hydrogen and helium produced in the Big Bang. This work, much of it carried out with inside stars; the Big Bang origin of the universe; and the current Dark Matter debate over what most of marked by this continual feedback between theory and experiment. Although Fowler was not directly

  12. Civilsamfundets ABC: M for Marked

    DEFF Research Database (Denmark)

    Lund, Anker Brink; Meyer, Gitte

    2016-01-01

    Bogstaveligt talt: Hvad er civilsamfundet? Anker Brink Lund og Gitte Meyer fra CBS Center for Civil Society Studies gennemgår civilsamfundet bogstav for bogstav. Vi er nået til M for Marked.......Bogstaveligt talt: Hvad er civilsamfundet? Anker Brink Lund og Gitte Meyer fra CBS Center for Civil Society Studies gennemgår civilsamfundet bogstav for bogstav. Vi er nået til M for Marked....

  13. Marks on the petroleum fiscality

    International Nuclear Information System (INIS)

    2007-02-01

    This document offers some marks on the petroleum fiscality in France: the taxes as the 'accises' and the 'TVA', the part of the taxes in the sale price at the service station, the comparison with other countries of Europe, the tax revenues and the Government budget. It provides also marks on the fuels prices formation (margins), the world petroleum markets (supply and demand) and the part of the petroleum companies on the petroleum market. (A.L.B.)

  14. Epistemologia pragmatyczna Michaela Williamsa (PRAGMATIST EPISTEMOLOGY BY MICHAEL WILLIAMS

    Directory of Open Access Journals (Sweden)

    Renata Ziemińska

    2007-06-01

    Full Text Available The article presents three main elements of Williams' epistemology: the concept of knowledge, the problem of skepticism and the concept of truth. Williams takes knowledge not as pure descriptive but partly normative concept (to know is to be engaged and entitled. He rejects the demonstrative conception of knowledge (knowledge is infallible and prefers the fallibilist conception of knowledge (knowledge is uncertain and fallible. Williams is good at bringing skeptical presuppositions to light: the demonstrative conception of knowledge and the conception of justification with Prior Grounding Requirement, epistemological realism and priority for internal knowledge. He rightly observes that when we change that presuppositions (skeptic's context, knowledge does exist. However, Williams-fallibilist is close to a skeptic: they both agree that our beliefs are uncertain. The difference is only whether some of our beliefs deserve to be called knowledge. The most important worries concern Williams' concept of truth (deflationary pragmatism. According to Williams truth has no nature and it is not a goal of inquiry. However, if truth is not a goal, we can hardly understand the previous discussion with skepticism and the defense of rationality.

  15. BWR Mark I pressure suppression study: bench mark experiments

    International Nuclear Information System (INIS)

    Lai, W.; McCauley, E.W.

    1977-01-01

    Computer simulations representative of the wetwell of Mark I BWR's have predicted pressures and related phenomena. However, calculational predictions for purposes of engineering decision will be possible only if the code can be verified, i.e., shown to compute in accord with measured values. Described in the report is a set of single downcomer spherical flask bench mark experiments designed to produce quantitative data to validate various air-water dynamic computations; the experiments were performed since relevant bench mark data were not available from outside sources. Secondary purposes of the study were to provide a test bed for the instrumentation and post-experiment data processing techniques to be used in the Laboratory's reactor safety research program and to provide additional masurements for the air-water scaling study

  16. William James, Gustav Fechner, and Early Psychophysics

    Directory of Open Access Journals (Sweden)

    Stephanie L. Hawkins

    2011-10-01

    Full Text Available American psychologist and philosopher William James devoted the entirety of his career to exploring the nature of volition, as expressed by such phenomena as will, attention, and belief. As part of that endeavor, James's unorthodox scientific pursuits, from his experiments with nitrous oxide and hallucinogenic drugs to his investigation of spiritualist mediums, represent his attempt to address the "hard problems" of consciousness for which his training in brain physiology and experimental psychology could not entirely account. As a student, James's reading in chemistry and physics had sparked his interest in the concepts of energy and force, terms that he later deployed in his writing about consciousness and in his arguments against philosophical monism and scientific materialism, as he developed his radically empiricist ideas privileging discontinuity and plurality. Despite James's long campaign against scientific materialism, he was, however, convinced of the existence of a naturalistic explanation for the more "wayward and fitful" aspects of mind, including transcendent experiences associated with hysteria, genius, and religious ecstasy. In this paper, I examine aspects of James's thought that are still important for contemporary debates in psychology and neuroscience: his "transmission theory" of consciousness, his ideas on the "knowing of things together," and, finally, the related concept of "the compounding of consciousness," which postulates the theoretical possibility for individual entities within a conscious system of thought to "know" the thoughts of others within the system. Taken together, these ideas suggest that James, in spite of, or perhaps because of, his forays into metaphysics, was working toward a naturalistic understanding of consciousness, what I will term a "distributive model," based on his understanding of consciousness as an "awareness" that interacts dynamically within, and in relation to, its environment.

  17. Metabolic abnormalities in Williams-Beuren syndrome.

    Science.gov (United States)

    Palacios-Verdú, María Gabriela; Segura-Puimedon, Maria; Borralleras, Cristina; Flores, Raquel; Del Campo, Miguel; Campuzano, Victoria; Pérez-Jurado, Luis Alberto

    2015-04-01

    Williams-Beuren syndrome (WBS, OMIM-194050) is a neurodevelopmental disorder with multisystemic manifestations caused by a 1.55-1.83 Mb deletion at 7q11.23 including 26-28 genes. Reported endocrine and metabolic abnormalities include transient hypercalcaemia of infancy, subclinical hypothyroidism in ∼ 30% of children and impaired glucose tolerance in ∼ 75% of adult individuals. The purpose of this study was to further study metabolic alterations in patients with WBS, as well as in several mouse models, to establish potential candidate genes. We analysed several metabolic parameters in a cohort of 154 individuals with WBS (data available from 69 to 151 cases per parameter), as well as in several mouse models with complete and partial deletions of the orthologous WBS locus, and searched for causative genes and potential modifiers. Triglyceride plasma levels were significantly decreased in individuals with WBS while cholesterol levels were slightly decreased compared with controls. Hyperbilirubinemia, mostly unconjugated, was found in 18.3% of WBS cases and correlated with subclinical hypothyroidism and hypotriglyceridemia, suggesting common pathogenic mechanisms. Haploinsufficiency at MLXIPL and increased penetrance for hypomorphic alleles at the UGT1A1 gene promoter might underlie the lipid and bilirubin alterations. Other disturbances included increased protein and iron levels, as well as the known subclinical hypothyroidism and glucose intolerance. Our results show that several unreported biochemical alterations, related to haploinsufficiency for specific genes at 7q11.23, are relatively common in WBS. The early diagnosis, follow-up and management of these metabolic disturbances could prevent long-term complications in this disorder. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  18. William Byrd: Political and Recusant Composer

    Directory of Open Access Journals (Sweden)

    Ariel Foshay Bacon

    2012-05-01

    Full Text Available Amidst the pendulum of political and religious upheaval that pervaded England throughout the sixteenth and seventeenth century, William Byrd stands as one of the best loved and lauded composers. Byrd succeeded in the secular and sacred realms, contributing great works to the Anglican Church, popularizing the English madrigal and producing prolific amounts of sacred music. However, in a time where one’s religious beliefs were often linked with political loyalty, Byrd defied his monarch’s established and enforced Protestant religion, composing politically charged music for recusant use in clandestine Catholic Church services. His themes were aligned with the Jesuit mission and his texts were often drawn from the lips of martyred Catholics at the gallows; their last words forever immortalized by Byrd for the furthering of the Jesuit cause and the Counter-Reformation. The examination of sources by prominent Byrd scholars, an analyses of Byrd’s ‘political’ compositions and a study of the social and historical background are used to place Byrd within the appropriate context, prove his recusant and political leanings, and analyze his precarious relationship with the English monarch, Elizabeth I. It is shown that Byrd could not have proceeded with his recusant practices, personally or musically, had it not been for his status as a composer, as well as Byrd’s shrewdness in procuring diplomatic relationships with high persons at court and with Queen Elizabeth I through the Chapel Royal. Finally, Byrd’s success at writing for the Anglican Church service and popular secular music showcased his ability to take a moderate stance in situations that benefitted his status with the crown

  19. Obituary: William A. Rense (1914-2008)

    Science.gov (United States)

    Cushman, Glen

    2009-12-01

    On March 28, 2008, the space research community lost another of its pioneers. William A. Rense, professor emeritus of physics at the University of Colorado in Boulder, who died in Estes Park, Colorado, following complications from cancer. He was 94. Bill, as he was widely known, was born in 1914 in Massillon, Ohio, the son of German immigrants. His was a large family - five brothers and one sister. His father, Joseph Rense, worked for the city of Cleveland while his mother, Rosalia (Luther) Rense was a housewife. As a child, Bill developed a love of astronomy which led him to earn a bachelor's degree in physics and astronomy from Case Western Reserve University in Cleveland, followed by master's and PhD degrees in physics at Ohio State University. He held teaching positions at Rutgers, University of Miami (Florida), Texas A & M, and Louisiana State University before taking his final appointment at CU in 1949. While teaching at LSU, he met and in 1942 married Wanda (Childs) Rense. In addition to teaching physics at CU, Bill did research in CU's Upper Air Laboratory. His early work there included studies of polarized light and its implications for the analysis of zodiacal light. He and his co-workers also began developing instrumentation to be flown above the Earth's atmosphere in sounding rockets. In 1952 he obtained the first photographic spectrogram of the solar Lyman-alpha line of hydrogen (121.6nm). This work was followed in 1956 by the first full disk spectroheliogram in Lyman-alpha. These results could not have been possible without the use of pointing control systems for sounding rockets. These "sun trackers" kept the payloads pointed at the sun long enough for the measurements to be made, and CU was a pioneer in their development. The expanding research venue led the Upper Air Laboratory to be renamed the Laboratory for Atmospheric and Space Physics (LASP), and Bill Rense was its first director. He continued his research into the properties of the solar

  20. ‘Wot larx!’: William Morris, Charles Dickens, and Fatherly Feelings

    Directory of Open Access Journals (Sweden)

    Wendy Parkins

    2011-09-01

    Full Text Available This essay explores the significance of William Morris’s reading of Dickens for Morris’s articulation of fatherly feelings. Recent scholarship on Victorian fatherhood has begun to overturn the stereotype of the dour, emotionally distant paterfamilias as providing only a partial understanding of forms of middle-class fatherhood and William Morris may serve as an example of a Victorian father whose parenting style eschewed detached authoritarianism, and instead combined nurture, play, and creativity. While Morris referred to Dickens’s works and characters in letters to a range of correspondents, his repeated usage of Joe Gargery’s catchphrase ‘Wot larx!’ (variously spelled occurs exclusively in letters to his wife and daughters, especially the latter. I will consider how the character of Joe Gargery, who combines nurturing tenderness with manly labour, was deployed by Morris to perform a playful and affectionate paternal persona. While Morris’s use of Joe’s catchphrase seems to express a spontaneous overflow of powerful feeling its status as a quotation also works to mark (and mask a disavowal of powerfully ambivalent feelings concerning his own emotional agency as husband and father.

  1. Mark Napier / Mark Napier ; interv. Tilman Baumgärtel

    Index Scriptorium Estoniae

    Napier, Mark

    2006-01-01

    Ameerika kunstnikust Mark Napierist (sünd. 1961) ja tema loomingust, 2001. a. tehtud meiliintervjuu kunstnikuga. Võrguteosest "The Digital Landfill" (1998), koos Andy Deckiga loodud tööst "GrafficJam" (1999), töödest "Shredder" (1998), "Feed", "Riot", "P-Soup" (2000), võrgukunstist ja muust

  2. Minimal Marking: A Success Story

    Directory of Open Access Journals (Sweden)

    Anne McNeilly

    2014-11-01

    Full Text Available The minimal-marking project conducted in Ryerson’s School of Journalism throughout 2012 and early 2013 resulted in significantly higher grammar scores in two first-year classes of minimally marked university students when compared to two traditionally marked classes. The “minimal-marking” concept (Haswell, 1983, which requires dramatically more student engagement, resulted in more successful learning outcomes for surface-level knowledge acquisition than the more traditional approach of “teacher-corrects-all.” Results suggest it would be effective, not just for grammar, punctuation, and word usage, the objective here, but for any material that requires rote-memory learning, such as the Associated Press or Canadian Press style rules used by news publications across North America.

  3. Percentage Retail Mark-Ups

    OpenAIRE

    Thomas von Ungern-Sternberg

    1999-01-01

    A common assumption in the literature on the double marginalization problem is that the retailer can set his mark-up only in the second stage of the game after the producer has moved. To the extent that the sequence of moves is designed to reflect the relative bargaining power of the two parties it is just as plausible to let the retailer move first. Furthermore, retailers frequently calculate their selling prices by adding a percentage mark-up to their wholesale prices. This allows a retaile...

  4. Recent paleoseismicity record in Prince William Sound, Alaska, USA

    Science.gov (United States)

    Kuehl, Steven A.; Miller, Eric J.; Marshall, Nicole R.; Dellapenna, Timothy M.

    2017-12-01

    Sedimentological and geochemical investigation of sediment cores collected in the deep (>400 m) central basin of Prince William Sound, along with geochemical fingerprinting of sediment source areas, are used to identify earthquake-generated sediment gravity flows. Prince William Sound receives sediment from two distinct sources: from offshore (primarily Copper River) through Hinchinbrook Inlet, and from sources within the Sound (primarily Columbia Glacier). These sources are found to have diagnostic elemental ratios indicative of provenance; Copper River Basin sediments were significantly higher in Sr/Pb and Cu/Pb, whereas Prince William Sound sediments were significantly higher in K/Ca and Rb/Sr. Within the past century, sediment gravity flows deposited within the deep central channel of Prince William Sound have robust geochemical (provenance) signatures that can be correlated with known moderate to large earthquakes in the region. Given the thick Holocene sequence in the Sound ( 200 m) and correspondingly high sedimentation rates (>1 cm year-1), this relationship suggests that sediments within the central basin of Prince William Sound may contain an extraordinary high-resolution record of paleoseismicity in the region.

  5. Celiac disease in patients with Williams-Beuren syndrome.

    Science.gov (United States)

    Mıhçı, Ercan; Nur, Banu Güzel; Berker-Karaüzüm, Sibel; Yılmaz, Aygen; Artan, Reha

    2015-01-01

    Celiac disease is an autoimmune, gastrointestinal disorder characterized by intolerance to the dietary grain protein gluten. An increased prevalence of celiac disease has been reported in Down syndrome and Turner syndrome, but there has been only few previous reports with respect to the association of celiac disease in Williams-Beuren syndrome. The aim of this study was to evaluate the frequency of celiac disease in our 24 Williams-Beuren syndrome patients. Gastrointestinal problems and celiac disease symptoms of patients were noted. All patients were analyzed by the titer of tissue transglutaminases IgA and IgG. HLA genotyping and intestinal biopsy was performed to the patients with positive serology. We also performed gluten free diet in the presence of compatible symptoms, serology, HLA genotyping and intestinal biopsy. In our study, two patients had positive tTG antibodies, but only one had positive biopsy finding for celiac disease. The frequency of celiac disease in patients with Williams-Beuren syndrome was estimated as 1/24 (4.1%). Though the number of participants in this study was limited, the results show that the frequency of celiac disease is higher in Williams-Beuren syndrome compared to the general population. We suggest that a high suspicion and testing for celiac disease should be recommended at certain intervals in all cases with Williams-Beuren syndrome to detect the cause of growth retardation and gastrointestinal problems.

  6. Williams Syndrome and 15q Duplication: Coincidence versus Association.

    Science.gov (United States)

    Khokhar, Aditi; Agarwal, Swashti; Perez-Colon, Sheila

    2017-01-01

    Williams syndrome is a multisystem disorder caused by contiguous gene deletion in 7q11.23, commonly associated with distinctive facial features, supravalvular aortic stenosis, short stature, idiopathic hypercalcemia, developmental delay, joint laxity, and a friendly personality. The clinical features of 15q11q13 duplication syndrome include autism, mental retardation, ataxia, seizures, developmental delay, and behavioral problems. We report a rare case of a girl with genetically confirmed Williams syndrome and coexisting 15q duplication syndrome. The patient underwent treatment for central precocious puberty and later presented with primary amenorrhea. The karyotype revealed 47,XX,+mar. FISH analysis for the marker chromosome showed partial trisomy/tetrasomy for proximal chromosome 15q (15p13q13). FISH using an ELN -specific probe demonstrated a deletion in the Williams syndrome critical region in 7q11.23. To our knowledge, a coexistence of Williams syndrome and 15q duplication syndrome has not been reported in the literature. Our patient had early pubertal development, which has been described in some patients with Williams syndrome. However, years later after discontinuing gonadotropin-releasing hormone analogue treatment, she developed primary amenorrhea.

  7. Prosodic Focus Marking in Bai.

    NARCIS (Netherlands)

    Liu, Zenghui; Chen, A.; Van de Velde, Hans

    2014-01-01

    This study investigates prosodic marking of focus in Bai, a Sino-Tibetan language spoken in the Southwest of China, by adopting a semi-spontaneous experimental approach. Our data show that Bai speakers increase the duration of the focused constituent and reduce the duration of the post-focus

  8. Better marking means cheaper pruning.

    Science.gov (United States)

    Kenneth R. Eversole

    1953-01-01

    Careful selection of trees to be pruned can make the difference between profit and loss on the pruning investment, especially in stands where no thinning is contemplated. Expert marking is required to make sure that the pruned trees will grow rapidly. The most important variable influencing the cost of clear wood produced by pruning is growth rate. For example, at 3...

  9. Laser marking method and device

    International Nuclear Information System (INIS)

    Okazaki, Yuki; Aoki, Nobutada; Mukai, Narihiko; Sano, Yuji; Yamamoto, Seiji.

    1997-01-01

    An object is disposed in laser beam permeating liquid or gaseous medium. Laser beams such as CW laser or pulse laser oscillated from a laser device are emitted to the object to apply laser markings with less degradation of identification and excellent corrosion resistance on the surface of the object simply and easily. Upon applying the laser markings, a liquid or gas as a laser beam permeating medium is blown onto the surface of the object, or the liquid or gas in the vicinity of the object is sucked, the laser beam-irradiated portion on the surface can be cooled positively. Accordingly, the laser marking can be formed on the surface of the object with less heat affection to the object. In addition, if the content of a nitrogen gas in the laser beam permeating liquid medium is reduced by degassing to lower than a predetermined value, or the laser beam permeating gaseous medium is formed by an inert gas, a laser marking having high corrosion resistance and reliability can be formed on the surface of the objective member. (N.H.)

  10. Comment on 'magnetosheath burst of predominantly medium nuclei observed with Imp 8 on February 16, 1974' by T. P. Armstrong, S. M. Krimigis, and R. P. Lepping

    Science.gov (United States)

    Hovestadt, D.

    1980-01-01

    Armstrong et al. (1978) have observed a unique series of bursts with an unusually high content of Z greater than 2 particles and a high degree of collimation from the direction of the sun. The bursts were observed only with the CPME (Charged Particle Measurement Instrument) on Imp 8, but not with the CPME on Imp 7 nor with the ULET (Ultralow Energy Telescope) on Imp 8, whose response characteristics matched those of the CPME on Imp 7. The present comparison of the measurements made with the CPME and ULET cast doubt on the correctness of the reported observations.

  11. Obituary: William K. Rose (1935-2010)

    Science.gov (United States)

    Trimble, Virginia

    2011-12-01

    Stellar astrophysicist William Kenneth Rose died near his home in Potomac, Maryland, on September 30, 2010, after an extended illness. Rose was the son of pharmacist Kenneth William Rose and Shirley Near Rose and was born in Ossining, New York, on August 10, 1935. He received an AB from Columbia College in 1957 and a PhD in physics from Columbia University in 1963, with a thesis on "measurements of linear polarization in discrete radio sources using a 9.4 cm maser," under the direction of Charles H. Townes. Rose played a major role in designing and constructing the maser and used it at a radio telescope at Maryland Point that belonged to the Naval Research Lab. He observed Jupiter and Saturn and a number of extra-solar-system sources, and also diffuse centimeter emission (see appendix). The thesis was not published in an archival journal, but can be found under Library of Congress code QB 475.R67. While in graduate School, Bill married Sheila Tuchman, whose primary scientific interests were biological. None of their three children chose to be scientists, but two are CPAs. Bill moved successfully through the academic hurdles) from a research position at Princeton (1963-67), where a collaboration with Nick Woolf and Martin Schwarzchild on the infrared spectra of giant stars became one of his most-cited papers, to assistant and associate professorships at MIT (1967-71), and then associate and full professorships at the University of Maryland (1971 to retirement in 2005). His most innovative work was probably that on nova explosions arising from degenerate ignition of hydrogen accreted on white dwarfs in close binary systems, published in 1968. The same idea occurred to others at about the same time, and Bill did not, perhaps, get quite his fair share of the credit. I first met Sheila and Bill in summer 1969 at the Stony Brook summer school on stellar evolution (not published until 1972). He lectured on the nature of nova explosions and on nuclear burning in thin

  12. Obituary: William L. Kraushaar, 1920-2008

    Science.gov (United States)

    Clark, George W.

    2009-01-01

    Professor William L. Kraushaar, a former MIT physics professor and a pioneer in the field of high-energy astronomy, died 21 March 2008 of complications from Parkinson's disease. He was 87. Kraushaar received his bachelor's degree from Lafayette College in 1942. During World War II he worked at the National Bureau of Standards on projects that included development of the proximity fuse for artillery shells. After the war he earned his doctorate at Cornell University. In 1949 Kraushaar was appointed research associate at MIT, where he made the first measurements of the mean life of the pi meson at the MIT electron synchrotron. Over the next fifteen years he rose through the faculty ranks, becoming a full professor before leaving MIT for the University of Wisconsin at Madison in 1965. In 1957 Kraushaar began a decade-long effort to map the sky in the "light" of cosmic gamma rays. Their detection promised to open new ways to investigate high-energy processes in the universe. Initial balloon-borne experiments failed due to background gamma rays generated in the residual atmosphere above the highest attainable altitudes. In 1958, Kraushaar seized a new opportunity for experiments above the atmosphere. Working with Professor George Clark, he directed the development in the MIT Laboratory for Nuclear Science of a gamma-ray detector for a satellite experiment that was launched in April 1961 as Explorer 11. It registered 31 events with the electronic signatures of cosmic gamma rays with energies greater than 50 MeV. Kraushaar then initiated a second and more refined experiment to be carried on OSO 3. In this project Kraushaar and Clark were joined by Gordon Garmire, a former student of Kraushaar. The OSO 3 experiment, launched in March of 1967, registered 621 cosmic gamma-ray events. It yielded the first all-sky map of high-energy cosmic gamma rays showing a concentration of gamma rays from directions in the Milky Way where gamma-ray producing interactions of charged cosmic

  13. William Barlow and the Determination of Atomic Arrangement in Crystals.

    Science.gov (United States)

    Mauskopf, Seymour H

    2015-04-01

    William Barlow (1845-1934) was an important if unconventional scientist, known for having developed the 'closest-packing' atomic models of crystal structure. He resumed an early nineteenth-century tradition of utilizing crystallographical and chemical data to determine atomic arrangements in crystals. This essay recounts Barlow's career and scientific activity in three parts: (a) His place in the tradition of determining atomic arrangement in context of this earlier tradition and of contemporaneous developments of crystallography and chemistry, (b) his unconventional career, and (c) the 'success' of his program to determine atomic arrangements in crystals and its influence on the work of William Lawrence Bragg.

  14. Automated road marking recognition system

    Science.gov (United States)

    Ziyatdinov, R. R.; Shigabiev, R. R.; Talipov, D. N.

    2017-09-01

    Development of the automated road marking recognition systems in existing and future vehicles control systems is an urgent task. One way to implement such systems is the use of neural networks. To test the possibility of using neural network software has been developed with the use of a single-layer perceptron. The resulting system based on neural network has successfully coped with the task both when driving in the daytime and at night.

  15. Mark Twain: inocente ou pecador? = Mark Twain: innocent or sinner?

    Directory of Open Access Journals (Sweden)

    Heloisa Helou Doca

    2009-01-01

    Full Text Available A leitura cuidadosa do texto do “Tratado de Paris”, em 1900, leva Mark Twain a concluir que a intenção política norte-americana era, claramente, a de subjugação. Declara-se, abertamente, antiimperialista, nesse momento, apesar das inúmeras críticasrecebidas por antagonistas políticos que defendiam o establishment dos Estados Unidos. Após viajar para a Europa e Oriente, em 1867, como correspondente do jornal Daily Alta Califórnia, Mark Twain publica, em 1869, seu relato de viagem, The Innocents Abroad or TheNew Pilgrim’s Progress. Nosso estudo demonstra que o autor, apesar das diversas máscaras usadas em seus relatos, narra histórias, culturas e tradições, tanto da Europa quanto do Oriente, já com os olhos bem abertos pelo viés antiimperialista. Faz uso da paródia, sátira, ironia e humor para dessacralizar impérios, monarcas e a Igreja que subjugavam os mais fracos, iluminando, desde então, os estudos sobre culturas. Nosso estudo, outrossim, faz uma reflexão sobre cultura, tradição e o olhar do viajante, justificando o “olhar inocente” do narrador em seu relato.After carefully reading the Treaty of Paris in 1900, Mark Twain concluded that the goal of U.S. policy was clearly one ofsubjugation. He openly declared himself an anti-imperialist at that time, in spite of the numerous criticisms he received from political opponents who supported the United States status quo. After traveling to Europe and the East in 1867 as a correspondent for The DailyAlta California newspaper, Mark Twain published his travel report, The Innocents Abroad or The New Pilgrim’s Progress in 1869. Our study demonstrates that the author, in spite of using different guises in his reports, narrated histories, cultures and traditions – from both Europe and the East – with a viewpoint already imbued by his anti-imperialistic ideals. Twain made use of parody, satire, irony and humor within his texts in order to desecrate empires,monarchs and

  16. Adaptive Functioning in Williams Syndrome: A Systematic Review

    Science.gov (United States)

    Brawn, Gabrielle; Porter, Melanie

    2018-01-01

    Literature on the level of adaptive functioning and relative strengths and weaknesses in functioning of individuals with Williams syndrome (WS) was reviewed. The electronic databases PsycINFO, PubMed, Expanded Academic, Web of Science, Scopus and ProQuest were searched electronically for relevant articles and dissertations using the search terms…

  17. Beyond Behaviour: Is Social Anxiety Low in Williams Syndrome?

    Science.gov (United States)

    Dodd, Helen F.; Schniering, Carolyn A.; Porter, Melanie A.

    2009-01-01

    Individuals with Williams syndrome (WS) exhibit striking social behaviour that may be indicative of abnormally low social anxiety. The present research aimed to determine whether social anxiety is unusually low in WS and to replicate previous findings of increased generalised anxiety in WS using both parent and self report. Fifteen individuals…

  18. Climatic data for Williams Lake, Hubbard County, Minnesota, 1985

    Science.gov (United States)

    Sturrock, A.M.; Rosenberry, D.O.; Winter, T.C.

    1987-01-01

    Research on the hydrology of Williams Lake, north-central Minnesota includes study of evaporation. Presented here are those climatic data needed for energy-budget and mass-transfer studies, including: water-surface temperature, dry-bulb and wet-bulb air temperatures, wind speed, precipitation, and solar and atmospheric radiation. Data are collected at raft and land stations.

  19. Climatic data for Williams Lake, Hubbard County, Minnesota, 1984

    Science.gov (United States)

    Sturrock, A.M.; Rosenberry, D.O.; Scarborough, J.L.; Winter, T.C.

    1986-01-01

    Research on the hydrology of Williams Lake, north-central Minnesota includes study of evaporation. Presented here are those climatic data needed for energy-budget and mass-transfer studies, including: water-surface temperature, dry-bulb and wet-bulb air temperatures, wind speed, precipitation, and solar and atmospheric radiation. Data are collected at raft and land stations.

  20. Climatic data for Williams Lake, Hubbard County, Minnesota, 1983

    Science.gov (United States)

    Sturrock, A.M.; Rosenberry, D.O.; Engelbrecht, L.G.; Gothard, W.A.; Winter, T.C.

    1984-01-01

    Research on the hydrology of Williams Lake, north-central Minnesota includes study of evaporation. Presented here are those climatic data needed for energy-budget and mass-transfer studies,including: water-surface temperature, dry-bulb and wet-bulb air temperatures, wind speed, precipitation, and solar radiation. Data are collected at raft and land stations.

  1. Edward Christopher Williams and His Impact on Librarianship.

    Science.gov (United States)

    Latimer, Carlos

    Edward Christopher Williams had a major impact on librarianship, not only as the first documented African American to graduate from a library school, but also as a developer of education for librarians and as an active member of the American Library Association (ALA) and the Ohio Library Association. This study used the historical methodology…

  2. Atypical Sleep Architecture and Altered EEG Spectra in Williams Syndrome

    Science.gov (United States)

    Gombos, F.; Bodizs, R.; Kovacs, I.

    2011-01-01

    Background: Williams syndrome (WS) is a neurodevelopmental genetic disorder characterised by physical abnormalities and a distinctive cognitive profile with intellectual disabilities (IDs) and learning difficulties. Methods: In our study, nine adolescents and young adults with WS and 9 age- and sex-matched typically developing (TD) participants…

  3. Astronaut William Fisher preparing to train in the WETF

    Science.gov (United States)

    1985-01-01

    Astronaut William Fisher is shown in his extravehicular mobility unit (EMU) preparing to train in the Weightless Environment Training Facility (WETF). He is wearing the communications carrier assembly but not the full helmet (32102); Reflections of the WETF can be seen on the closed visor of the EMU helmet Fiser is wearing (32103).

  4. I Know! It's Backwards Day! Gender Roles and William's Doll

    Science.gov (United States)

    Van de Kleut, Geraldine

    2007-01-01

    This article presents a case study of an exploration of gender roles in a second-grade classroom. The author discusses some of the discursive identities in which she and her students are positioned, and then uses the picture book William's Doll to introduce a discussion of discursive gender identities with her students. She then asks students to…

  5. Elicited Production of Relative Clauses in Children with Williams Syndrome

    Science.gov (United States)

    Zukowski, Andrea

    2009-01-01

    Relative clauses have been implicated alternately as a strength and a weakness in the language of people with Williams Syndrome (WS). To clarify the facts, an elicited production test was administered to 10 people with WS (age 10-16 years), 10 typically developing children (age 4-7 years), and 12 typically developing adults. Nearly every WS…

  6. Shepard Award Winners, Part 2: Dr. Tracie Williams

    Centers for Disease Control (CDC) Podcasts

    2009-07-29

    This podcast highlights the accomplishments of Dr. Tracie Williams, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 7/29/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/29/2009.

  7. Orientation Perception in Williams Syndrome: Discrimination and Integration

    Science.gov (United States)

    Palomares, Melanie; Landau, Barbara; Egeth, Howard

    2009-01-01

    Williams Syndrome (WS) is a rare neurodevelopmental disorder, which stems from a genetic deletion on chromosome 7 and causes a profound weakness in visuospatial cognition. Our current study explores how orientation perception may contribute to the visuospatial deficits in WS. In Experiment 1, we found that WS individuals and normal 3-4 year olds…

  8. How Executive Functions Are Related to Intelligence in Williams Syndrome

    Science.gov (United States)

    Osorio, Ana; Cruz, Raquel; Sampaio, Adriana; Garayzabal, Elena; Martinez-Regueiro, Rocio; Goncalves, Oscar F.; Carracedo, Angel; Fernandez-Prieto, Montse

    2012-01-01

    Williams syndrome is characterized by impairments in executive functions (EFs). However, it remains unknown how distinct types of EFs relate to intelligence in this syndrome. The present study analyzed performance on working memory, inhibiting and shifting, and its links to IQ in a sample of 17 individuals with WS, and compared them with a group…

  9. Biblionef SA: Bringing books to the bookless | Williams | Innovation

    African Journals Online (AJOL)

    Biblionef SA: Bringing books to the bookless. Jean Williams. Abstract. No abstract available. Innovation (2003) No. 26, pp 43-47. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

  10. William Shakespeare’s“Hamlet”and Oedipus Complex

    Institute of Scientific and Technical Information of China (English)

    迪丽努尔

    2014-01-01

    “Hamlet”is one of the great dramas of William Shakespeare. This paper by describing the relationship between Hamlet and his mother, the Ghost and his uncle, tries to approve that Oedipus complex is the main reason of Hamlet’s kil ing his uncle.

  11. Sir William Jenner (1815-1898) and Queen Victoria.

    Science.gov (United States)

    Seddon, David; Queen Victoria

    2004-08-01

    This biographical note outlines the work of Sir William Jenner (1815-1898), court physician 1861-93 and President of the Royal College of Physicians 1881-8. He was the first to distinguish between typhoid and typhus both clinically and pathologically.

  12. A Conversation with William A. Fowler Part II

    Science.gov (United States)

    Greenberg, John

    2005-06-01

    Physicist William A.Fowler initiated an experimental program in nuclear astrophysics after World War II. He recalls here the Steady State versus Big Bang controversy and his celebrated collaboration with Fred Hoyle and Geoffrey and Margaret Burbidge on nucleosynthesis in stars. He also comments on the shift away from nuclear physics in universities to large accelerators and national laboratories.

  13. Florence Jessie MacWilliams (1917-1990)

    Indian Academy of Sciences (India)

    famous mathematician Oscar Zariski, well known for his work in algebraic geometry, at. Johns Hopkins University, following him to Harvard University to study with him for a year. There was a break in her studies for many years following her marriage in 1941 to. W al ter Mac Williams, an engineer, and the birth and raising of ...

  14. La Fondation William et Flora Hewlett | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    La Fondation William et Flora Hewlett. http://www.hewlett.org/ · What we do · Funding · Resources · About IDRC. Knowledge. Innovation. Solutions. Careers · Contact Us · Site map. Sign up now for IDRC news and views sent directly to your inbox each month. Subscribe · Copyright · Open access policy · Privacy policy ...

  15. William Knocke receives 2008 Virginia Outstanding Civil Engineer Award

    OpenAIRE

    Daniilidi, Christina

    2008-01-01

    William R. Knocke, W.C. English Professor and head of the Charles E. Via, Jr. Department of Civil and Environmental Engineering at Virginia Tech, was awarded the 2008 Virginia Outstanding Civil Engineer Award at the Virginia Section of the American Society of Civil Engineers' (ASCE) banquet, held recently in Williamsburg, Va.

  16. 77 FR 76414 - William D. Ford Federal Direct Loan Program

    Science.gov (United States)

    2012-12-28

    ... Federal Direct Loan Program AGENCY: Department of Education. ACTION: Final regulations; correction... Loan (Perkins Loan) Program; the Federal Family Education Loan (FFEL) Program; and the William D. Ford Federal Direct Loan (Direct Loan) Program, including the Public Service Loan Forgiveness (PSLF) Program...

  17. 77 FR 72960 - William D. Ford Federal Direct Loan Program

    Science.gov (United States)

    2012-12-07

    ... Federal Direct Loan Program AGENCY: Office of Postsecondary Education, Department of Education. ACTION... document to establish the date for the early implementation of William D. Ford Federal Direct Loan (Direct Loan) program regulations that establish a new income-contingent repayment plan based on the President...

  18. Perceptual Speech and Paralinguistic Skills of Adolescents with Williams Syndrome

    Science.gov (United States)

    Hargrove, Patricia M.; Pittelko, Stephen; Fillingane, Evan; Rustman, Emily; Lund, Bonnie

    2013-01-01

    The purpose of this research was to compare selected speech and paralinguistic skills of speakers with Williams syndrome (WS) and typically developing peers and to demonstrate the feasibility of providing preexisting databases to students to facilitate graduate research. In a series of three studies, conversational samples of 12 adolescents with…

  19. Williams Syndrome: Daily Challenges and Positive Impact on the Family

    Science.gov (United States)

    Scallan, Susan; Senior, Joyce; Reilly, Colin

    2011-01-01

    Background: Despite the distinctive physical, cognitive, personality and behavioural characteristics associated with Williams syndrome, few studies to date have examined parental experiences of raising a child with this genetic syndrome. Methods: This explorative pilot study employed predominantly qualitative methodologies via face-to-face…

  20. Language and Literacy Development of Children with Williams Syndrome

    Science.gov (United States)

    Mervis, Carolyn B.

    2009-01-01

    Williams syndrome is a rare neurodevelopmental disorder caused by deletion of approximately 25 genes on chromosome 7q11.23. Children with the syndrome evidence large individual differences in both broad language and reading abilities. Nevertheless, as a group, children with this syndrome show a consistent pattern characterized by relative…

  1. Advocating for Inclusion of Children with Williams Syndrome

    Science.gov (United States)

    Self, Michelle A.

    2010-01-01

    The purpose of this study was to describe and explore the experience of inclusion of students with Williams syndrome, a rare genetic condition of a microdeletion on chromosome 7 which has medical, behavior, and cognitive issues. The study was conducted by gaining an understanding from the parents' point of view. The study was twofold. First, the…

  2. Gender Attribution and Gender Agreement in French Williams Syndrome

    Science.gov (United States)

    Boloh, Yves; Ibernon, Laure; Royer, Stephanie; Escudier, Frederique; Danillon, Aurelia

    2009-01-01

    Previous studies on grammatical gender in French individuals with Williams syndrome (WS) have led to conflicting findings and interpretations regarding keys abilities--gender attribution and gender agreement. New production data from a larger SW sample (N = 24) showed that gender attribution scores in SW participants exactly mirrored those of…

  3. Examining Reports of Mental Health in Adults with Williams Syndrome

    Science.gov (United States)

    Stinton, Chris; Tomlinson, Katie; Estes, Zachary

    2012-01-01

    Prior research suggests that individuals with Williams syndrome (WS) have a disposition towards anxiety. Information regarding this is typically derived from parents and carers. The perspectives of the individuals with WS are rarely included in research of this nature. We examined the mental health of 19 adults with WS using explicit (psychiatric…

  4. Electrophysiological Correlates of Semantic Processing in Williams Syndrome

    Science.gov (United States)

    Pinheiro, Ana P.; Galdo-Alvarez, Santaigo; Sampaio, Adriana; Niznikiewicz, Margaret; Goncalves, Oscar F.

    2010-01-01

    Williams syndrome (WS), a genetic neurodevelopmental disorder due to microdeletion in chromosome 7, has been described as a syndrome with an intriguing socio-cognitive phenotype. Cognitively, the relative preservation of language and face processing abilities coexists with severe deficits in visual-spatial tasks, as well as in tasks involving…

  5. Comprehension of Metaphor and Metonymy in Children with Williams Syndrome

    Science.gov (United States)

    Annaz, Dagmara; Van Herwegen, Jo; Thomas, Michael; Fishman, Roza; Karmiloff-Smith, Annette; Rundblad, Gabriella

    2009-01-01

    Background: Figurative language, such as metaphor and metonymy, is very common in daily language use. Its underlying cognitive processes are sometimes viewed as lying at the interface of language and thought. Williams syndrome, which is a rare genetic developmental disorder, provides an opportunity to study this interface because individuals with…

  6. The Interplay between Anxiety and Social Functioning in Williams Syndrome

    Science.gov (United States)

    Riby, Deborah M.; Hanley, Mary; Kirk, Hannah; Clark, Fiona; Little, Katie; Fleck, Ruth; Janes, Emily; Kelso, Linzi; O'Kane, Fionnuala; Cole-Fletcher, Rachel; Allday, Marianne Hvistendahl; Hocking, Darren; Cornish, Kim; Rodgers, Jacqui

    2014-01-01

    The developmental disorder Williams syndrome (WS) has been associated with an atypical social profile of hyper-sociability and heightened social sensitivity across the developmental spectrum. In addition, previous research suggests that both children and adults with WS have a predisposition towards anxiety. The current research aimed to explore…

  7. Visually Guided Step Descent in Children with Williams Syndrome

    Science.gov (United States)

    Cowie, Dorothy; Braddick, Oliver; Atkinson, Janette

    2012-01-01

    Individuals with Williams syndrome (WS) have impairments in visuospatial tasks and in manual visuomotor control, consistent with parietal and cerebellar abnormalities. Here we examined whether individuals with WS also have difficulties in visually controlling whole-body movements. We investigated visual control of stepping down at a change of…

  8. Musicality Correlates with Sociability and Emotionality in Williams Syndrome

    Science.gov (United States)

    Ng, Rowena; Lai, Philip; Levitin, Daniel J.; Bellugi, Ursula

    2013-01-01

    Williams syndrome (WS) is a neurogenetic developmental disorder characterized by peaks and valleys of cognitive abilities. One peak that has been understudied is the affinity that many individuals with WS have with music. It remains unknown whether their high levels of musical interest, skill, and expressivity are related to their sociable…

  9. Pulmonary arterial stent implantation in an adult with Williams syndrome

    NARCIS (Netherlands)

    Reesink, Herre J.; Henneman, Onno D. F.; van Delden, Otto M.; Biervliet, Jules D.; Kloek, Jaap J.; Reekers, Jim A.; Bresser, Paul

    2007-01-01

    We report a 38-year-old patient who presented with pulmonary hypertension and right ventricular dysfunction due to pulmonary artery stenoses as a manifestation of Williams syndrome, mimicking chronic thromboembolic pulmonary hypertension. The patient was treated with balloon angioplasty and stent

  10. The use of emotions in narratives in Williams syndrome.

    Science.gov (United States)

    Van Herwegen, Jo; Aznar, Ana; Tenenbaum, Harriet

    2014-01-01

    Although individuals with Williams syndrome are very sociable, they tend to have limited contact and friendships with peers. In typically developing children the use of positive emotions (e.g., happy) has been argued to be related to peer relationships and popularity. The current study investigated the use and development of emotion words in Williams syndrome using cross-sectional developmental trajectories and examined children's use of different types of emotion words. Nineteen children with Williams syndrome (WS) and 20 typically developing (TD) children matched for chronological age told a story from a wordless picture book. Participants with WS produced a similar number of emotion words compared to the control group and the use of emotion words did not change when plotted against chronological age or vocabulary abilities in either group. However, participants with WS produced more emotion words about sadness. Links between emotion production and friendships as well as future studies are discussed. After reading this article, readers will be able to: explain the development of positive and negative emotions in Williams syndrome and recognize that emotion production is atypical in this population. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Characterisation of Sleep Problems in Children with Williams Syndrome

    Science.gov (United States)

    Annaz, Dagmara; Hill, Catherine M.; Ashworth, Anna; Holley, Simone; Karmiloff-Smith, Annette

    2011-01-01

    Sleep is critical to optimal daytime functioning, learning and general health. In children with established developmental disorders sleep difficulties may compound existing learning difficulties. The purpose of the present study was to evaluate the prevalence and syndrome specificity of sleep problems in Williams syndrome (WS), a…

  12. Comparison of the acute effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    Purpose: To assess the effect of the crude methanol leaf extracts of Tulbaghia violacea William Henry Harvey (Alliaceae) on blood pressure (BP) and heart rate in ageing normotensive Wistar Kyoto rats (WKY), and compare the results obtained with those for adult spontaneously hypertensive rats (SHR). Methods: T.

  13. Potential Beneficial Effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    Tulbaghia violacea William Henry Harvey (Harv. Alliaceae) is a small bulbous herb belonging to the family Alliaceae. It is used in South Africa to treat fever, colds, asthma, paralysis, and hypertension. Meanwhile, cardiovascular disease accounts for about 30 % of total global death, with most of these deaths occurring in low ...

  14. Personal Space Regulation in Williams Syndrome: The Effect of Familiarity

    Science.gov (United States)

    Lough, Emma; Flynn, Emma; Riby, Deborah M.

    2016-01-01

    Personal space refers to a protective barrier that we strive to maintain around our body. We examined personal space regulation in young people with Williams syndrome (WS) and their typically developing, chronological age-matched peers using a parent report questionnaire and a stop-distance paradigm. Individuals with WS were reported by their…

  15. ProRisk : risk analysis instrument : developed for William properties

    NARCIS (Netherlands)

    van Doorn, W.H.W.; Egeberg, Ingrid; Hendrickx, Kristoff; Kahramaner, Y.; Masseur, B.; Waijers, Koen; Weglicka, K.A.

    2005-01-01

    This report presents a Risk Analysis Instrument developed for William Properties. Based on the analysis, it appears that the practice of Risk Analysis exists within the organization, yet rather implicit. The Risk Analysis Instrument comes with a package of four components: an activity diagram, a

  16. Experiences of Bullying for Individuals with Williams Syndrome

    Science.gov (United States)

    Fisher, Marisa H.; Lough, Emma; Griffin, Megan M.; Lane, Laurel A.

    2017-01-01

    Background: Individuals with intellectual disability experience high rates of bullying, but it is not known how people with specific syndromes, such as Williams syndrome (WS), experience and respond to bullying. Given their behavioral profile, including hypersociability and heightened anxiety, and their risk for experiencing other forms of…

  17. Word-Preserving Arts: Material Inscription, Ekphrasis, and Spatial Form in the Later Work of William Wordsworth

    DEFF Research Database (Denmark)

    Simonsen, Peter

    William Wordsworth, posterity, reading, material inscription, ekphrasis, description, sonnet, portraiture......William Wordsworth, posterity, reading, material inscription, ekphrasis, description, sonnet, portraiture...

  18. Recent results for Mark III

    International Nuclear Information System (INIS)

    Brient, J.C.

    1987-12-01

    This paper presents recent results from the Mark III detector at SPEAR, in the open charm sector. The first topic discussed is the reanalysis of the direct measurement of the D hadronic branching fractions, where a detailed study has been made of the Cabibbo suppressed and multi-π 0 's D decays backgrounds in the double tag sample. Next, the Dalitz plot analysis of the D decays to Kππ is presented, leading to the relative fractions of three-body versus pseudoscalarvector decays. 7 refs., 5 figs

  19. The Mark III vertex chamber

    International Nuclear Information System (INIS)

    Adler, J.; Bolton, T.; Bunnell, K.

    1987-07-01

    The design and construction of the new Mark III vertex chamber is described. Initial tests with cosmic rays prove the ability of track reconstruction and yield triplet resolutions below 50 μm at 3 atm using argon/ethane (50:50). Also performed are studies using a prototype of a pressurized wire vertex chamber with 8 mm diameter straw geometry. Spatial resolution of 35mm was obtained using dimethyl ether (DME) at 1 atm and 30 μm using argon/ethane (50/50 mixture) at 4 atm. Preliminary studies indicate the DME to adversely affect such materials as aluminized Mylar and Delrin

  20. 46 CFR 185.602 - Hull markings.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Hull markings. 185.602 Section 185.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.602 Hull markings. (a) Each vessel must be marked as required by part 67...

  1. 27 CFR 28.193 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.193... Drawback Filing of Notice and Removal § 28.193 Export marks. In addition to the marks and brands required... chapter, the exporter shall mark the word “Export” on the Government side of each case or Government head...

  2. 27 CFR 28.103 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.103... Manufacturing Bonded Warehouse § 28.103 Export marks. (a) General. In addition to the marks and brands required... provisions of part 19 of this chapter, the proprietor shall mark the word “Export” on the Government side of...

  3. 27 CFR 28.144 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.144... § 28.144 Export marks. (a) General Requirement. In addition to the marks and brands required to be... brewer shall mark the word “Export” on each container or case of beer, or the words “Beer concentrate for...

  4. 27 CFR 28.154 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.154..., for Exportation or Transfer to a Foreign-Trade Zone § 28.154 Export marks. In addition to the marks... provisions of part 19 of this chapter, the proprietor shall mark the word “Export” on the Government side of...

  5. 33 CFR 161.60 - Vessel Traffic Service Prince William Sound.

    Science.gov (United States)

    2010-07-01

    ... William Sound. 161.60 Section 161.60 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Movement Reporting System Areas and Reporting Points § 161.60 Vessel Traffic Service Prince William Sound... Cape Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between...

  6. 75 FR 16159 - Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) Charter Renewal

    Science.gov (United States)

    2010-03-31

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard [USCG-2010-0121] Prince William Sound Regional... the Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) as an alternative voluntary advisory group for Prince William Sound, Alaska. This certification allows the PWSRCAC to monitor the...

  7. 77 FR 19301 - Prince William Sound Regional Citizens' Advisory Council Charter Renewal

    Science.gov (United States)

    2012-03-30

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard [USCG-2012-0099] Prince William Sound Regional... Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) as an alternative voluntary advisory group for Prince William Sound, Alaska. This certification allows the PWSRCAC to monitor the activities...

  8. 33 CFR 165.1704 - Prince William Sound, Alaska-regulated navigation area.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Prince William Sound, Alaska... District § 165.1704 Prince William Sound, Alaska-regulated navigation area. (a) The following is a... Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between 146°30′ W...

  9. 76 FR 1187 - Application for Recertification of Prince William Sound Regional Citizens' Advisory Council

    Science.gov (United States)

    2011-01-07

    ... Prince William Sound Regional Citizens' Advisory Council AGENCY: Coast Guard, DHS. ACTION: Notice of... on, the application for recertification submitted by the Prince William Sound Regional Citizen's... advisory group in lieu of a Regional Citizens' Advisory Council for Prince William Sound, Alaska. This...

  10. Probed Serial Recall in Williams Syndrome: Lexical Influences on Phonological Short-Term Memory

    Science.gov (United States)

    Brock, Jan; McCormack, Teresa; Boucher, Jill

    2005-01-01

    Williams syndrome is a genetic disorder that, it has been claimed, results in an unusual pattern of linguistic strengths and weaknesses. The current study investigated the hypothesis that there is a reduced influence of lexical knowledge on phonological short-term memory in Williams syndrome. Fourteen children with Williams syndrome and 2…

  11. Outcome in Adult Life for People with Williams Syndrome Results from a Survey of 239 Families

    Science.gov (United States)

    Howlin, P.; Udwin, O.

    2006-01-01

    BACKGROUND: Although there has been considerable research into the genotype and phenotype of Williams syndrome, there have been relatively few studies of long-term prognosis. As a preliminary to a more detailed investigation of adults with Williams syndrome, a parental questionnaire was distributed to members of the UK Williams Syndrome…

  12. 77 FR 47374 - Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal...

    Science.gov (United States)

    2012-08-08

    ...; William D. Ford Federal Direct Loan (Direct Loan) Program/ Federal Family Loan (FFEL) Program: Deferment... which borrowers in the William D. Ford Federal Direct Loan (Direct Loan) and Federal Family Education... considered public records. Title of Collection: William D. Ford Federal Direct Loan (Direct Loan) Program...

  13. 78 FR 11857 - Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan...

    Science.gov (United States)

    2013-02-20

    ...; Comment Request; William D. Ford Federal Direct Loan Program (DL) Regulations AGENCY: Department of... in response to this notice will be considered public records. Title of Collection: William D. Ford.... Abstract: The William D. Ford Federal Direct Loan Program regulations cover areas of program administration...

  14. 77 FR 43276 - Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal...

    Science.gov (United States)

    2012-07-24

    ...; William D. Ford Federal Direct Loan Program General Forbearance Request SUMMARY: Borrowers who receive loans through the William D. Ford Federal Direct Loan Program will use this form to request forbearance... considered public records. Title of Collection: William D. Ford Federal Direct Loan Program General...

  15. Seasonal distribution of Dall's porpoise in Prince William Sound, Alaska

    Science.gov (United States)

    Moran, John R.; O'Dell, Matthew B.; Arimitsu, Mayumi L.; Straley, Janice M.; Dickson, Danielle M. S.

    2018-01-01

    Dall's porpoise, Phocoenoides dalli, are a conspicuous predator in the Prince William Sound ecosystem, yet there has been little effort directed towards monitoring this species since the 1980s, prior to the Exxon Valdez oil spill. We used vessel-based surveys to examine the seasonal distribution of Dall's porpoise in the waters of Prince William Sound during eight years from 2007 to 2015. Over the course of 168 days and 15,653 km of survey effort, 921 Dall's porpoise were encountered in 210 groups. We estimate an encounter rate of 0.061 porpoise/km traveled or 1 porpoise encountered for every 16.5 km traveled. Dall's porpoise were found throughout the year in Prince William Sound, and used a wide range of habitats, including those not considered typical of the species, such as bays, shallow water, and nearshore waters. Dall's porpoise seasonally shifted their center of distribution from the western passages in fall to the bays of the eastern Sound in winter and spring. Dall's porpoises were widely dispersed throughout the Sound in summer. We identified potential Dall's porpoise habitat (depth, slope, and distance from shore) within Prince William Sound using generalized additive models (GAM). Dall's porpoise were found in deeper water during summer and in shallowest water during spring. We propose that their use of novel habitats is a function of reduced predation risk associated with the decline of their main predator, killer whales (Orcinus orca), following the Exxon Valdez oil spill, and the presence of overwintering and spawning Pacific herring (Clupea pallasii). While the size of the Dall's porpoise population within Prince William Sound remains unknown, our encounter rates were lower than those reported in the 1970s. Their high metabolic rate and ubiquitous presence makes them one of the more important, yet understudied, forage fish predators in the region.

  16. Interview with Professor Mark Wilcox.

    Science.gov (United States)

    Wilcox, Mark

    2016-08-01

    Mark Wilcox speaks to Georgia Patey, Commissioning Editor: Professor Mark Wilcox is a Consultant Microbiologist and Head of Microbiology at the Leeds Teaching Hospitals (Leeds, UK), the Professor of Medical Microbiology at the University of Leeds (Leeds, UK), and is the Lead on Clostridium difficile and the Head of the UK C. difficile Reference Laboratory for Public Health England (PHE). He was the Director of Infection Prevention (4 years), Infection Control Doctor (8 years) and Clinical Director of Pathology (6 years) at the Leeds Teaching Hospitals. He is Chair of PHE's Rapid Review Panel (reviews utility of infection prevention and control products for National Health Service), Deputy Chair of the UK Department of Health's Antimicrobial Resistance and Healthcare Associated Infection Committee and a member of PHE's HCAI/AR Programme Board. He is a member of UK/European/US working groups on C. difficile infection. He has provided clinical advice as part of the FDA/EMA submissions for the approval of multiple novel antimicrobial agents. He heads a healthcare-associated infection research team at University of Leeds, comprising approximately 30 doctors, scientists and nurses; projects include multiple aspects of C. difficile infection, diagnostics, antimicrobial resistance and the clinical development of new antimicrobial agents. He has authored more than 400 publications, and is the coeditor of Antimicrobial Chemotherapy (5th/6th/7th Editions, 15 December 2007).

  17. Dialectica Interpretation with Marked Counterexamples

    Directory of Open Access Journals (Sweden)

    Trifon Trifonov

    2011-01-01

    Full Text Available Goedel's functional "Dialectica" interpretation can be used to extract functional programs from non-constructive proofs in arithmetic by employing two sorts of higher-order witnessing terms: positive realisers and negative counterexamples. In the original interpretation decidability of atoms is required to compute the correct counterexample from a set of candidates. When combined with recursion, this choice needs to be made for every step in the extracted program, however, in some special cases the decision on negative witnesses can be calculated only once. We present a variant of the interpretation in which the time complexity of extracted programs can be improved by marking the chosen witness and thus avoiding recomputation. The achieved effect is similar to using an abortive control operator to interpret computational content of non-constructive principles.

  18. Cavernous hemangioma presenting marked hyperostosis

    International Nuclear Information System (INIS)

    Kobata, Hitoshi; Miyake, Hiroji; Kitamura, Junji; Kajikawa, Hiroshi; Ohta, Tomio

    1988-01-01

    The authors report here a case of hemangioma of the left parietal bone which presented headache and papilledema. This patient is a 37-year-old female who had, prior to admission, complained of increasing headache for one year and blurred vision for three months. She had no history of head injury. Local physical examinations revealed a slight bulging in her left parietal region which was insensitive to palpation and not adherent to the overlying scalp. Neurological examinations revealed bilateral papilledema and an incongruous bitemporal upper quadrant defect in the visual field. All the other neurological and laboratory data were normal. A plain skull roentogenogram showed a 9 x 9 cm osteolytic and characteristic honeycomb lesion in the parietal region. Systemic bone survey revealed a similar lesion in the right tibia which was not histologically examined. A marked accumulation of isotopes was detected on the bone scintigrams at both lesions. Selective external carotid angiograms demonstrated a tumor stain fed by the superficial temporal, occipital, and middle meningial arteries. CT scans of the brain and skull clearly showed a local thickening of and structural changes in the skull bone and also a mass effect on the brain and lateral ventricle. The lesioned bone was removed en bloc and replaced by an artificial bone. It was highly vascular, but not adherent to the overlying dura. The post-operative course was uneventful, and the headache and papilledema disappeared. Hemangioma of the skull presenting marked hyperostosis, as reported above, seems to be rare. In addition, in this case, skeletal angioma without any clinical manifestation was detected. Clinical and radiological pictures of the hemangioma of the skull and other bones were briefly discussed. (author)

  19. Haploinsufficiency of BAZ1B contributes to Williams syndrome through transcriptional dysregulation of neurodevelopmental pathways.

    Science.gov (United States)

    Lalli, Matthew A; Jang, Jiwon; Park, Joo-Hye C; Wang, Yidi; Guzman, Elmer; Zhou, Hongjun; Audouard, Morgane; Bridges, Daniel; Tovar, Kenneth R; Papuc, Sorina M; Tutulan-Cunita, Andreea C; Huang, Yadong; Budisteanu, Magdalena; Arghir, Aurora; Kosik, Kenneth S

    2016-04-01

    Williams syndrome (WS) is a neurodevelopmental disorder caused by a genomic deletion of ∼28 genes that results in a cognitive and behavioral profile marked by overall intellectual impairment with relative strength in expressive language and hypersocial behavior. Advancements in protocols for neuron differentiation from induced pluripotent stem cells allowed us to elucidate the molecular circuitry underpinning the ontogeny of WS. In patient-derived stem cells and neurons, we determined the expression profile of the Williams-Beuren syndrome critical region-deleted genes and the genome-wide transcriptional consequences of the hemizygous genomic microdeletion at chromosome 7q11.23. Derived neurons displayed disease-relevant hallmarks and indicated novel aberrant pathways in WS neurons including over-activated Wnt signaling accompanying an incomplete neurogenic commitment. We show that haploinsufficiency of the ATP-dependent chromatin remodeler, BAZ1B, which is deleted in WS, significantly contributes to this differentiation defect. Chromatin-immunoprecipitation (ChIP-seq) revealed BAZ1B target gene functions are enriched for neurogenesis, neuron differentiation and disease-relevant phenotypes. BAZ1B haploinsufficiency caused widespread gene expression changes in neural progenitor cells, and together with BAZ1B ChIP-seq target genes, explained 42% of the transcriptional dysregulation in WS neurons. BAZ1B contributes to regulating the balance between neural precursor self-renewal and differentiation and the differentiation defect caused by BAZ1B haploinsufficiency can be rescued by mitigating over-active Wnt signaling in neural stem cells. Altogether, these results reveal a pivotal role for BAZ1B in neurodevelopment and implicate its haploinsufficiency as a likely contributor to the neurological phenotypes in WS. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  20. Ischemic Stroke in Williams-Beuren Syndrome: A Case Report

    Directory of Open Access Journals (Sweden)

    Wei-Der Lee

    2009-04-01

    Full Text Available A 15-year-old girl was admitted because of an acute onset of facial palsy and right hemiparesis. The patient had a history of moderate mental retardation and developmental delay. On admission, her vital signs were stable, except for high blood pressure. Magnetic resonance imaging demonstrated an infarct involving the left internal capsule and putamen. Because of the patient's young age, an extensive stroke survey was performed. Williams-Beuren syndrome was finally confirmed by fluorescent in situ hybridization. Compared with the previously reported cases, no evidence of cerebral arterial stenosis or cardiac abnormalities was found by noninvasive imaging techniques. Because Williams-Beuren syndrome is a complex, multiple congenital anomaly syndrome with prominent cardiovascular features, regular assessment and antihypertensive treatment are necessary to minimize the lifelong cardiovascular risk in patients with this syndrome.

  1. Williams syndrome and mature B-Leukemia: A random association?

    Science.gov (United States)

    Decimi, Valentina; Fazio, Grazia; Dell'Acqua, Fabiola; Maitz, Silvia; Galbiati, Marta; Rizzari, Carmelo; Biondi, Andrea; Cazzaniga, Giovanni; Selicorni, Angelo

    2016-12-01

    Williams syndrome (WBS) is a rare neurodevelopmental disorder with specific phenotypic characteristics and cardiac abnormalities, but is not considered as a cancer predisposing condition. However, in rare cases, malignancies have been described in patients with WBS, with hematologic cancer (mainly Burkitt Lymphoma and Acute Lymphoblastic Leukemia) as the most represented. We report here the case of a boy with WS and B-NHL. This is the unique case within the large cohort of patients (n = 117) followed in our institution for long time (mean clinical follow-up, 13 years). We herewith propose that the BCL7B gene, located in the chromosomal region commonly deleted in Williams syndrome, could potentially have a role in this particular association. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  2. Obituary: William Merz Sinton, 1925-2004

    Science.gov (United States)

    Spencer, John Robert

    2004-12-01

    Bill Sinton, one of the pioneers of infrared planetary astronomy, died at his home in Flagstaff, Arizona, on March 16th 2004, at the age of 78. Bill was born in Baltimore on April 11, 1925. He developed lifelong interests in railroads and radios while still a child, and by age 15 he had already built a shortwave radio receiver and won his ham radio license. His abiding interest in electronic and mechanical devices would serve him well in his professional career. He fought with the 26th Infantry Division in the Second World War and was wounded in France in October 1944. After the war he obtained his bachelor's degree in physics at Johns Hopkins (1949). His doctoral work at the same institution, with John Strong, gave him his first taste of infrared astronomy, including the first measurements of the moon at 1-millimeter wavelength. He obtained his PhD, on the infrared spectrum and temperature of Venus, in 1953. During a 1-year postdoc at Johns Hopkins he probed the lunar subsurface by observing the cooling of the moon during eclipse at millimeter wavelengths, and observed the diurnal variation in Martian surface temperatures in the 10-micron window. He joined Harvard College Observatory as a research associate and lecturer in 1954, and became interested in the question of life on Mars and the then-plausible possibility that Mars's dark markings were due to vegetation. In 1956, using a monochromator that he built himself, he detected absorptions near 3.4 microns in the Martian spectrum which he attributed to a C-H stretch transition in Martian vegetation. These "Sinton bands," as they came to be known, sparked great interest at the time, and though at least some of the spectral structure was later found to be due to terrestrial HDO, and the presence of abundant organic molecules on the Martian surface was finally ruled out by the Viking landers, some of the spectral features that he detected appear to be intrinsic to Mars and are still not well understood. In 1957

  3. Climatic data for Williams Lake, Hubbard County, Minnesota, 1982

    Science.gov (United States)

    Rosenberry, D.O.; Sturrock, A.M.; Scarborough, J.L.; Winter, T.C.

    1988-01-01

    Research on the hydrology of Williams Lake, north-central Minnesota includes study of evaporation. Those climatic data needed for energy budget and mass transfer studies are presented , including: water surface temperature, dry-bulb and wet-bulb air temperatures, wind speed, precipitation, and solar and atmospheric radiation. Some calculated values necessary for these studies are also presented, such as vapor pressure and Bowen-ratio values. Data are collected at raft and land stations.

  4. Climatic data for Williams Lake, Hubbard County, Minnesota, 1986

    Science.gov (United States)

    Rosenberry, D.O.; Sturrock, A.M.; Winter, T.C.

    1988-01-01

    Research on the hydrology of Williams Lake, north-central Minnesota includes study of evaporation. Presented here are those climatic data needed for energy-budget and mass-transfer studies, including: water-surface temperature, dry-bulb and wet-bulb air temperatures, wind speed, precipitation, and solar and atmospheric radiation. Some calculated values necessary for these studies, such as vapor pressure and Bowen ratio numbers, also are presented. Data are collected at raft and land stations.

  5. William Gaddis’s Immortality: Celebration, Cartoon, or Corruption?

    OpenAIRE

    Alberts, Crystal

    2013-01-01

    Although ostensibly a review of 'The Letters of William Gaddis' edited by Steven Moore (Champaign: Dalkey Archive, 2013), this article evaluates Moore’s volume in light of generally accepted practices of scholarly editions and the handling of historical documents. In particular, Alberts compares some of Moore’s edited letters to the originals housed either at Washington University in St. Louis or the Harry Ransom Center at the University of Texas, Austin and reveals issues involving the repre...

  6. Morphological differences in the mirror neuron system in Williams Syndrome

    OpenAIRE

    Ng, Rowena; Brown, Timothy T.; Erhart, Matthew; Järvinen, Anna M.; Korenberg, Julie R.; Bellugi, Ursula; Halgren, Eric

    2015-01-01

    Williams syndrome (WS) is a genetic condition characterized by an overly gregarious personality, including high empathetic concern for others. Although seemingly disparate from the profile of autism spectrum disorder (ASD), both are associated with deficits in social communication/cognition. Notably, the mirror neuron system (MNS) has been implicated in social dysfunction for ASD; yet, the integrity of this network and its association with social functioning in WS remains unknown. Magnetic re...

  7. William J. Donovan: Visionary, Strategic Leader, an Historical Perspective

    Science.gov (United States)

    1991-05-03

    War II years until his death . 1945 through 1959. Strategy, without Information on which It can rely, is helpless. Information Is useless unless It Is...was again emulating his Rough Rider hero, because like him, he was now a cavalryman.32 Donovan had never been a horseman or soldier before, but like...Intelligence officer and Chief of Combined Operatlrns during World War II, said of General William Donovan In 1966, seven years after his death , "This

  8. The development of perceptual grouping in infants with Williams syndrome

    OpenAIRE

    Farran, E. K.; Brown, J. H.; Cole, V. L.; Houston-Price, C.; Karmiloff-Smith, A.

    2007-01-01

    Perceptual grouping by luminance similarity and by proximity was investigated in infants with Williams syndrome (WS) aged between 6 and 36 months (visit 1, N=29). WS infants who were still under 36 months old, 8 months later, repeated the testing procedure (visit 2, N=15). Performance was compared to typically developing (TD) infants aged from 2 to 20 months (N=63). Consistent with the literature, TD participants showed grouping by luminance at the youngest testing age, 2 months. Grouping by ...

  9. William H. Sheldon and the culture of the somatotype

    OpenAIRE

    Gatlin, Stephen H.

    1997-01-01

    The burden of this dissertation is to show that William Sheldon's somatotype project should be seen as an integral aspect of modernist culture. Sheldon engaged the same problems with modernity and the "Second Industrial Revolution" (urbanization, overpopulation, industrialization, alienation) that confronted modernist poets, novelists, and philosophers. In this I am elaborating Dorothy Ross's recent metaphor, "modernist impulses in the human sciences" (1994). Both scientists and artists were ...

  10. La Fondation William et Flora Hewlett | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    La Fondation William et Flora Hewlett. http://www.hewlett.org/. Initiative Think tank. Cette initiative permet d'établir des organismes indépendants qui se consacrent à la recherche et à l'élaboration de politiques dans des pays en développement. Voir davantage. Initiative Think tank. Croissance de l'économie et débouchés ...

  11. Sleep-EEG in dizygotic twins discordant for Williams syndrome.

    Science.gov (United States)

    Bódizs, Róbert; Gombos, Ferenc; Szocs, Katalin; Réthelyi, János M; Gerván, Patrícia; Kovács, Ilona

    2014-01-30

    Reports on twin pairs concordant and discordant for Williams syndrome were published before, but no study unravelled sleep physiology in these cases yet. We aim to fill this gap by analyzing sleep records of a twin pair discordant for Williams syndrome extending our focus on presleep wakefulness and sleep spindling. We performed multiplex ligation-dependent probe amplification of the 7q11.23 region of a 17 years old dizygotic opposite-sex twin pair discordant for Williams syndrome. Polysomnography of laboratory sleep at this age was analyzed and followed-up after 1.5 years by ambulatory polysomnography. Sleep stages scoring, EEG power spectra and sleep spindle analyses were carried out. The twin brother showed reduced levels of amplification for all of the probes in the 7q11.23 region indicating a typical deletion spanning at least 1.038 Mb between FKBP6 and CLIP2. The results of the twin sister showed normal copy numbers in the investigated region. Lower sleep times and efficiencies, as well as higher slow wave sleep percents of the twin brother were evident during both recordings. Roughly equal NREM, Stage 2 and REM sleep percents were found. EEG analyses revealed state and derivation-independent decreases in alpha power, lack of an alpha spectral peak in presleep wakefulness, as well as higher NREM sleep sigma peak frequency in the twin brother. Faster sleep spindles with lower amplitude and shorter duration characterized the records of the twin brother. Spectra show a striking reliability and correspondence between the two situations (laboratory vs. home records). Alterations in sleep and specific neural oscillations including the alpha/sigma waves are inherent aspects of Williams syndrome.

  12. Parents perceptions of social inclusion for children with Williams Syndrome

    OpenAIRE

    Gulliver, Katherine

    2016-01-01

    This thesis explores parents’ perceptions of social inclusion for children with Williams Syndrome; a rare intellectual disability with a distinct social cognitive profile. 5 interviews with parents give rich understanding to what parents’ value for their child’s education, and how this is achieved. Thematic analysis highlights key similarities and differences in experiences between parents of children attending mainstream schools and one special school. Severity of disability affects how pare...

  13. Generalized Bragg-Williams method for 'antiferromagnetic' lattice gases

    International Nuclear Information System (INIS)

    Osorio, R.

    1983-01-01

    The many-sublattice Bragg-Williams approximation of statistical mechanics is applied to the two-dimensional square and triangular lattice-gas models with nearest-neighbor repulsive interactions. Each problem is solved through both the canonical and grand-canonical methods. The present treatment emphasizes the duality between concentration and chemical potential and illustrates the appearance of first- and second -order transitions in each method. (Author) [pt

  14. Fissured and geographic tongue in Williams-Beuren syndrome

    Directory of Open Access Journals (Sweden)

    Neeta Sharma

    2014-01-01

    Full Text Available Williams-Beuren Syndrome (WBS is a rare, most often sporadic, genetic disease caused by a chromosomal microdeletion at locus 7q11.23 involving 28 genes. It is characterized by congenital heart defects, neonatal hypercalcemia, skeletal and renal abnormalities, cognitive disorder, social personality disorder, and dysmorphic facies. A number of clinical findings has been reported, but none of the studies evaluated this syndrome considering oral cavity. We here report a fissured and geographic tongue in association with WBS.

  15. OBITUARY: Sir William Mitchell Physicist and enthusiast for science

    CERN Multimedia

    Cowley, R

    2002-01-01

    "William Mitchell was successively head of Physics at Reading and Oxford universities, and Chairman of the Science and Engineering Research Council from 1985 to 1990. He is largely responsible for the excellent neutron and X-ray facilities that are available for research by scientists in the UK. He was one of the first to realise that these uniquely powerful facilities would be essential tools not only for physicists but also for chemists, biologists, materials scientists and engineers" (1 page).

  16. Cooperative Shark Mark Recapture Database (MRDBS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Shark Mark Recapture Database is a Cooperative Research Program database system used to keep multispecies mark-recapture information in a common format for...

  17. On-road Bicycle Pavement Markings

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — A mile by mile breakdown of the on-street bicycle pavement markings installed within the City of Pittsburgh. These include bike lanes, shared lane markings...

  18. Serviceable pavement marking retroreflectivity levels : technical report.

    Science.gov (United States)

    2009-03-01

    This research addressed an array of issues related to measuring pavement markings retroreflectivity, factors : related to pavement marking performance, subjective evaluation process, best practices for using mobile : retroreflectometers, sampling pav...

  19. MacWilliams Identity for M-Spotty Weight Enumerator

    Science.gov (United States)

    Suzuki, Kazuyoshi; Fujiwara, Eiji

    M-spotty byte error control codes are very effective for correcting/detecting errors in semiconductor memory systems that employ recent high-density RAM chips with wide I/O data (e.g., 8, 16, or 32bits). In this case, the width of the I/O data is one byte. A spotty byte error is defined as random t-bit errors within a byte of length b bits, where 1 le t ≤ b. Then, an error is called an m-spotty byte error if at least one spotty byte error is present in a byte. M-spotty byte error control codes are characterized by the m-spotty distance, which includes the Hamming distance as a special case for t =1 or t = b. The MacWilliams identity provides the relationship between the weight distribution of a code and that of its dual code. The present paper presents the MacWilliams identity for the m-spotty weight enumerator of m-spotty byte error control codes. In addition, the present paper clarifies that the indicated identity includes the MacWilliams identity for the Hamming weight enumerator as a special case.

  20. Who Invented the Word Asteroid: William Herschel or Stephen Weston?

    Science.gov (United States)

    Cunningham, Clifford J.; Orchiston, Wayne

    2011-11-01

    William Herschel made the first serious study of 1 Ceres and 2 Pallas in the year 1802. He was moved by their dissimilarities to the other planets to coin a new term to distinguish them. For this purpose he enlisted the aid of his good friends William Watson and Sir Joseph Banks. Watson gave him a long list of possible names, which Herschel rejected. With a lifetime of experience classifying and naming newly found objects in nature, Banks became the man both Erasmus Darwin (in 1781) and William Herschel (in 1802) turned to for sage advice in developing a new descriptive language. In the case of Ceres and Pallas, Banks turned the task over to his friend, the noted philologist Stephen Weston, FRS. It has recently been stated by a noted British historian that it was Weston - not Herschel - who coined the term 'asteroid' to collectively describe Ceres and Pallas. This claim is investigated, and parallels are drawn in the use of neologism in astronomy and botany.

  1. [Marked hemosiderosis in myelodysplastic syndrome].

    Science.gov (United States)

    Klinz, C

    1999-01-29

    A 68-year-old man was admitted because of symptoms of lumbar pain. He was known to have chronic anemia with ring sideroblasts and diabetes melitus and to be in heart failure. Three months before he had been given 7 units of red cell concentrate. On admission the outstanding features were brown discoloration of the skin, absent body hair, tachycardia, hepatomegaly and small testicles. He had a normocytic anemia, hyperglycemia and raised transaminases, hypogonadism and vitamin D3 deficiency. The serum levels of iron, transferrin saturation and feritin were markedly elevated. Liver iron content/g dried liver was 4.2 g (by biomagnetometer). Radiology of the lumbar vertebrae showed osteoporosis and sonography confirmed hepatomegaly. The known myelodysplastic syndrome (MDS) had fed to secondary hemosiderosis with heart failure, liver involvement, diabetes mellitus, hypogonadism and osteoporosis. Symptomatic treatment was unsuccessfully complemented by desferoxamine (up to 4 g/12 h) to release iron. But very good iron excretion was then achieved with deferiprone (3 x 1 g/d). The patient later died of the sequelae of hemosiderosis. Even when they have not required transfusions, patients with long-standing MDS should be examined regularly for the possible development of secondary hemosiderosis so that iron-chelating agents can be administered as needed.

  2. EDMS - Reaching the Million Mark

    CERN Multimedia

    2009-01-01

    When Christophe Seith from the company Cegelec sat down to work on 14 May 2009 at 10:09 a.m. to create the EDMS document entitled "Rapport tournée PH semaine 20", little did he know that he would be the proud creator of the millionth EDMS document and the happy prize winner of a celebratory bottle of champagne to mark the occasion. In the run up to the creation of the millionth EDMS document the EDMS team had been closely monitoring the steady rise in the EDMS number generator, so as to ensure the switch from the six figured i.d. to seven figures would run smoothly and of course, to be able to congratulate the creator of the millionth EDMS document. From left to right: Stephan Petit (GS-ASE- EDS Section Leader), Christophe Delamare (GS- ASE Group Leader), Christophe Seith, creator of the millionth EDMS document, David Widegren, (GS-ASE- EPS Section Leader). The millionth EDMS document. For t...

  3. 46 CFR 122.602 - Hull markings.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Hull markings. 122.602 Section 122.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150....602 Hull markings. (a) Each vessel must be marked as required by part 67, subpart I, of this chapter...

  4. 7 CFR 160.32 - Marking containers.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Marking containers. 160.32 Section 160.32 Agriculture... STANDARDS FOR NAVAL STORES Analysis, Inspection, and Grading on Request § 160.32 Marking containers. The interested person shall provide any labor necessary for marking the containers, after the contents have been...

  5. 46 CFR 160.176-23 - Marking.

    Science.gov (United States)

    2010-10-01

    ... of the vessel. (2) The type of vessel. (3) Specific purpose or limitation approved by the Coast Guard...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Inflatable Lifejackets § 160.176-23 Marking. (a) General. Each inflatable lifejacket must be marked with the information required by this section. Each marking must be...

  6. 27 CFR 28.123 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.123..., or Transportation to a Manufacturing Bonded Warehouse § 28.123 Export marks. (a) General. In addition... filled under the provisions of part 24 of this chapter, the proprietor shall mark the word “Export” on...

  7. 27 CFR 28.223 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.223... Export marks. In addition to the marks and brands required to be placed on kegs, barrels, cases, crates... “Export” on each container or case before removal for export, for use on vessels or aircraft, or for...

  8. Dreamers in dialogue: evolution, sex and gender in the utopian visions of William Morris and William Henry Hudson

    Directory of Open Access Journals (Sweden)

    Caterina Novák

    2013-12-01

    Full Text Available The aim of this article is to explore the parallels between two late-nineteenth-century utopias,William Henry Hudsons A Crystal Age (1882 and William Morriss News from Nowhere (1891. Itaims to explore how these two works respond to the transition from a kinetic to a static conception ofutopia that under pressure from evolutionary and feminist discourses took place during the period.Particular focus lies on the way in which this is negotiated through the depiction of evolution, sexuality,and gender roles in the respective novels, and how the depiction of these disruptive elements may workas a means of ensuring the readers active engagement in political, intellectual and emotional terms.

  9. On Reading Poems: Visual & Verbal Icons in William Carlos Williams' «Landscape With The Fall Of Icarus»

    Directory of Open Access Journals (Sweden)

    Irene R. Fairley

    1981-09-01

    Full Text Available Williams' admiration for Brueghel's landscape is coded in structural and stylistic correspondences between the poem and the painting. Structures in the poem have effects analogous to the use of devices of color, line, foregrounding in the painting. The poem, like the painting, presents a «neutral» scene but subtly insures the reader's involvement. Further, Williams draws a visual statement so that graphic features suggest a global image isomorphic with the motif of descent. Features of the poem, such as line and clause length, syntactic construction, semantic coherence, are discussed as factors that contribute to rapid glancing and increase readability. A study of readers shows their sensitivity to graphic features including the poem's shape, and corroborates the importance of stylistic features.

  10. Assessment of Intellectual and Visuo- Spatial Abilities in Children and Adults with Williams Syndrome / Evaluación de habilidades intelectuales y visuoespaciales de niños y adultos con Síndrome de Williams

    Directory of Open Access Journals (Sweden)

    Maria Cristina Teixeira

    2013-06-01

    Full Text Available The Williams-Beuren syndrome (SWB, also known as Williams syndrome, is a contiguous gene deletion of the region 7q.11.23. The main clinical characteristics are typical faces, supravalvular aortic stenosis, failure to thrive, short stature, transient neonatal hypercalcemia, delayed language, friendly personality, hyperacusis and intellectual disability. The diagnosis of SWB is confirmed by the detection of micro deletion by different techniques of molecular cytogenetics, FISH, MLPA or polymorphic markers. This study assessed the verbal intelligence quotient (IQ and performance and visuospatial skills in children and adults with WBS. The composed group was of 31 WBS patients (19 M and 12 F, whose ages ranged from 9 to 26 years (M 14.45 y. All patients had the diagnosis confirmed molecularly. The tests used were the WISC-III, WAIS-III and Rey-Osterrieth Complex Figure Test. The results indicated a total IQ ranged from 51 to 86 (M 63: 22 with mild intellectual disability, 4 with moderate intellectual disability, 4 borderlines and 1 below the normal media. All patients had marked visual-spatial deficits. The results suggest nonverbal reasoning, visuo-spatial perception, spatial representation, working memory, motor planning and executive functions are very affected in this group.

  11. High contrast laser marking of alumina

    International Nuclear Information System (INIS)

    Penide, J.; Quintero, F.; Riveiro, A.; Fernández, A.; Val, J. del; Comesaña, R.; Lusquiños, F.; Pou, J.

    2015-01-01

    Highlights: • Laser marking of alumina using near infrared (NIR) lasers was experimentally analyzed. • Color change produced by NIR lasers is due to thermally induced oxygen vacancies. • Laser marking results obtained using NIR lasers and green laser are compared. • High contrast marks on alumina were achieved. - Abstract: Alumina serves as raw material for a broad range of advanced ceramic products. These elements should usually be identified by some characters or symbols printed directly on them. In this sense, laser marking is an efficient, reliable and widely implemented process in industry. However, laser marking of alumina still leads to poor results since the process is not able to produce a dark mark, yielding bad contrast. In this paper, we present an experimental study on the process of marking alumina by three different lasers working in two wavelengths: 1064 nm (Near-infrared) and 532 nm (visible, green radiation). A colorimetric analysis has been carried out in order to compare the resulting marks and its contrast. The most suitable laser operating conditions were also defined and are reported here. Moreover, the physical process of marking by NIR lasers is discussed in detail. Field Emission Scanning Electron Microscopy, High Resolution Transmission Electron Microscopy and X-ray Photoelectron Spectroscopy were also employed to analyze the results. Finally, we propose an explanation for the differences of the coloration induced under different atmospheres and laser parameters. We concluded that the atmosphere is the key parameter, being the inert one the best choice to produce the darkest marks

  12. William Gaddis’s Immortality: Celebration, Cartoon, or Corruption?

    Directory of Open Access Journals (Sweden)

    Crystal Alberts

    2013-11-01

    Full Text Available Although ostensibly a review of 'The Letters of William Gaddis' edited by Steven Moore (Champaign: Dalkey Archive, 2013, this article evaluates Moore’s volume in light of generally accepted practices of scholarly editions and the handling of historical documents. In particular, Alberts compares some of Moore’s edited letters to the originals housed either at Washington University in St. Louis or the Harry Ransom Center at the University of Texas, Austin and reveals issues involving the representation of the archival material, inconsistencies in editorial principles, and a misattributed letter, among other things.

  13. Seguridad social, empleo y propiedad privada en William Beveridge

    Directory of Open Access Journals (Sweden)

    Claudio Llanos Reyes

    2013-09-01

    Full Text Available This article aims to approach the economic and political notions of William Beveridge, which proposed the construction of the British Welfare State immediately after WWII. A form of State which sought to overcome the crisis of capitalism by proposing control over the system. We attempt to demonstrate the relation that should exist, according to Beveridge, the "father" of this model of capitalist State, between the development of a social security system, employment, and the situation of private property, while simultaneously pointing out the specifics and complexity of his ideas in the relation observed between full occupation and private property as basic elements for the construction of a Social Security system.

  14. [Sir William Richard Gowers: author of the "bible of neurology"].

    Science.gov (United States)

    Hirose, Genjiro

    2014-11-01

    William Richard Gowers is one of the great pioneers in neurology and the author of the well-known neurology textbook, "A Manual of Diseases of the Nervous System." His concepts of neurology are based on meticulously and carefully accumulated knowledge of history, observations, and neurological examinations of patients with various neurological diseases. He is not only a great neurologist but also a great teacher who loves teaching students and physicians through well-prepared lectures. We can glean the essence of the field of neurology through his life story and numerous writings concerning neurological diseases.

  15. Categories are alive: interview with Brackette F. Williams

    OpenAIRE

    Durão, Susana; Bastos, Cristiana; Williams, Brackette F.

    2013-01-01

    Brackette F. Williams is an American anthropologist and a Senior Justice ­Advocate, currently an associate professor of Cultural Anthropology at the University of ­Arizona. She studied at the University of Cornell, the University of Arizona, and received her doctorate from Johns Hopkins University. Her work interweaves ­matters of race, gender, class, ideology and politics in a unique manner – as seen in the article “A class act: Anthropology and the race to nation across ethnic terrain” (Ann...

  16. The other Dr Hooker: William Dawson Hooker (1816-40).

    Science.gov (United States)

    Lambert, Harold

    2011-11-01

    William Hooker and his son Joseph were famous as botanists and as the creators of the Royal Botanic Gardens in Kew. Joseph was famous also as the friend and mentor of Charles Darwin. But there was another brother, a little older than Joseph, also a doctor and naturalist. He went to Jamaica in the interests of his health and soon died there of yellow fever. His life was short and tragic with a medical conundrum at its end but its story also illustrates many of the beliefs and concerns that preoccupied doctors in this early Victorian era. It also illustrates the close relationship between medicine and botany that prevailed then.

  17. Pulmonary Arterial Stent Implantation in an Adult with Williams Syndrome

    International Nuclear Information System (INIS)

    Reesink, Herre J.; Henneman, Onno D. F.; Delden, Otto M. van; Biervliet, Jules D.; Kloek, Jaap J.; Reekers, Jim A.; Bresser, Paul

    2007-01-01

    We report a 38-year-old patient who presented with pulmonary hypertension and right ventricular dysfunction due to pulmonary artery stenoses as a manifestation of Williams syndrome, mimicking chronic thromboembolic pulmonary hypertension. The patient was treated with balloon angioplasty and stent implantation. Short-term follow-up showed a good clinical result with excellent patency of the stents but early restenosis of the segments in which only balloon angioplasty was performed. These stenoses were subsequently also treated successfully by stent implantation. Stent patency was observed 3 years after the first procedure

  18. Unravelling starlight: William and Margaret Huggins and the rise of the new astronomy

    National Research Council Canada - National Science Library

    Becker, Barbara J

    2011-01-01

    ...). A pioneer in adapting the spectroscope to new astronomical purposes, William Huggins rose to scientific prominence in London and transformed professional astronomy to become a principal founder...

  19. Converging Ideologies in William Fowler’s Hybrid Translation of Machiavelli’s Il Principe

    Directory of Open Access Journals (Sweden)

    Sergi Mainer

    2014-02-01

    Full Text Available This article explores the place of William Fowler’s translation of Machiavelli’s Prince in the Scottish Jacobean polysystem. Even if it was never finished, Fowler may have seen his rendering of Il Principe as a way of gaining King James’s favor at a time when Fowler had become a peripheral member at the sovereign’s court. Consequently, the translator’s hybrid deployment of three different sources, together with his own additions and suppressions, were aimed to conform to James VI’s political and cultural project. The ideological convergences between the king’s political thought and Fowler’s manipulated Prince supported and legitimized the existing power structures of the target culture. The unfinished/unedited state of the manuscript may suggest that a total reconciliation between James’s markedly idealized vision of kingship and government and Machiavelli’s treatise was impossible despite the translator’s intercultural and ethnocentric appropriation of the source text.

  20. Leftward lateralization of auditory cortex underlies holistic sound perception in Williams syndrome.

    Science.gov (United States)

    Wengenroth, Martina; Blatow, Maria; Bendszus, Martin; Schneider, Peter

    2010-08-23

    Individuals with the rare genetic disorder Williams-Beuren syndrome (WS) are known for their characteristic auditory phenotype including strong affinity to music and sounds. In this work we attempted to pinpoint a neural substrate for the characteristic musicality in WS individuals by studying the structure-function relationship of their auditory cortex. Since WS subjects had only minor musical training due to psychomotor constraints we hypothesized that any changes compared to the control group would reflect the contribution of genetic factors to auditory processing and musicality. Using psychoacoustics, magnetoencephalography and magnetic resonance imaging, we show that WS individuals exhibit extreme and almost exclusive holistic sound perception, which stands in marked contrast to the even distribution of this trait in the general population. Functionally, this was reflected by increased amplitudes of left auditory evoked fields. On the structural level, volume of the left auditory cortex was 2.2-fold increased in WS subjects as compared to control subjects. Equivalent volumes of the auditory cortex have been previously reported for professional musicians. There has been an ongoing debate in the neuroscience community as to whether increased gray matter of the auditory cortex in musicians is attributable to the amount of training or innate disposition. In this study musical education of WS subjects was negligible and control subjects were carefully matched for this parameter. Therefore our results not only unravel the neural substrate for this particular auditory phenotype, but in addition propose WS as a unique genetic model for training-independent auditory system properties.

  1. Mark II magnetic detector for SPEAR

    International Nuclear Information System (INIS)

    Larsen, R.R.

    1975-01-01

    The Mark II Detector, presently in the design stage, is a SLAC/LBL detector project to replace the Mark I now in operation at SPEAR. While similar in concept to the Mark I it will have improved momentum resolution, shower detection, solid angle coverage for both triggering and tracking and a magnet design providing easier access to those particles transmitted through the aluminum coil

  2. An analysis of hospital brand mark clusters.

    Science.gov (United States)

    Vollmers, Stacy M; Miller, Darryl W; Kilic, Ozcan

    2010-07-01

    This study analyzed brand mark clusters (i.e., various types of brand marks displayed in combination) used by hospitals in the United States. The brand marks were assessed against several normative criteria for creating brand marks that are memorable and that elicit positive affect. Overall, results show a reasonably high level of adherence to many of these normative criteria. Many of the clusters exhibited pictorial elements that reflected benefits and that were conceptually consistent with the verbal content of the cluster. Also, many clusters featured icons that were balanced and moderately complex. However, only a few contained interactive imagery or taglines communicating benefits.

  3. Pre-spill shoreline mapping in Prince William Sound, Alaska

    International Nuclear Information System (INIS)

    Owens, E.H.; Lamarche, A.; Reimer, P.D.; Marchant, S.O.; O'Brien, D.K.

    2003-01-01

    A long-term shoreline mapping program has been initiated in Prince William Sound, Alaska, to generate pre-spill data to assist in the planning activities for oil spill response in the area. Low-altitude aerial videotape surveys and video images form the basis for the mapping effort. The coast was initially divided into alongshore segments. The physical shore-zone is relatively homogeneous within each segment. A pre-spill Shoreline Cleanup Assessment Team (SCAT) database, using the ShoreData software, was created based on this initial detailed mapping. The SCAT field teams are therefore equipped with a detailed analysis of the shore-zone character. The same information was also used to develop a separate database for use by planning and response operations groups. The data is entered into the Graphical Resource Database (GRD), and a Geographic Information System (GIS). A simplified characterization of the primary features of each segment is then made available through interpretation of the data. In the event of an oil spill, the SCAT data in the ShoreData files can be combined with field data on shoreline oiling conditions using a second software package called ShoreAccess R which provides summaries of the main parameters required by the planning group. It can also be used as a data storage and management tool. As part of this program, more than 1700 kilometres of shoreline in Prince William Sound have already been mapped. 24 refs., 4 tabs., 5 figs

  4. Sir William Osler's speech at Troy: a Trojan horse?

    Science.gov (United States)

    Moran, Michael E

    2012-01-01

    Troy, New York, is a city of 55,000 people in upstate New York located along the Hudson River. A city of surprisingly rich cultural heritage, it was the home of New York state's first hospital outside New York City. The 50th anniversary celebration of Troy's hospital brought William Osler to the city as the keynote speaker. This speech, delivered on November 28, 1900, is one of Sir William's less well known addresses. Osler began his comments with Sir Thomas More's Utopia and talked at length about the hospital, its obligations, the influences it has upon the community, and the role of physicians and surgeons. He broached one of his old saws, the salary of attending physicians and their needed role in hospital management. His words were published in the diamond jubilee's records, but the hospital did not outlive its prominent guest professor, and it closed its doors in 1914. Just like the great historical city of Troy, New York's own Troy was on the brink of decline, and its hospital would be the first fatality. Therefore, it is almost prescient that the words of Osler, taken into historical context juxtaposed against the socioeconomic forces at work, are akin to the Greek's offering of a wooden edifice to end the Trojan War.

  5. 49 CFR 1520.13 - Marking SSI.

    Science.gov (United States)

    2010-10-01

    ... SECURITY INFORMATION § 1520.13 Marking SSI. (a) Marking of paper records. In the case of paper records... back cover, including a binder cover or folder, if the document has a front and back cover; (2) Any.... 552 and 49 CFR parts 15 and 1520. (d) Other types of records. In the case of non-paper records that...

  6. Lessons learned : pavement marking warranty contract.

    Science.gov (United States)

    2013-12-01

    In 2012, UDOT implemented a performance-based warranty on a portion of an I-15 pavement marking : project. The awarded contract requested a contractor warranty on the implemented markings for a total : duration of six years. This is the first time th...

  7. 49 CFR 178.338-18 - Marking.

    Science.gov (United States)

    2010-10-01

    ... pounds. (7) Maximum design density of lading (Max. Lading density), in pounds per gallon. (8) Material... cryogenic liquid, in hours, and the name of that cryogenic liquid (MRHT __ hrs, name of cryogenic liquid). Marked rated holding marking for additional cryogenic liquids may be displayed on or adjacent to the...

  8. 25 CFR 141.16 - Price marking.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Price marking. 141.16 Section 141.16 Indians BUREAU OF... AND ZUNI RESERVATIONS General Business Practices § 141.16 Price marking. The price of each article... visible to the customer and that affords the customer a reasonable opportunity to learn the price of the...

  9. Do employers prefer Mark over Mohammed?

    NARCIS (Netherlands)

    Iris Andriessen; Eline Nievers; Laila Faulk; Jaco Dagevos

    2010-01-01

    Original title: Liever Mark dan Mohammed? Does Mohammed have less chance of succeeding on the Dutch labour market than Mark, even though they both have the same qualifications and work experience? And are employers less friendly towards Sonaya than Paula? This study investigates the

  10. 7 CFR 956.162 - Container markings.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Container markings. 956.162 Section 956.162... WALLA VALLEY OF SOUTHEAST WASHINGTON AND NORTHEAST OREGON Rules and Regulations § 956.162 Container markings. Effective April 15, 1997, no handler shall ship any container of Walla Walla Sweet Onions except...

  11. Neglected aspects and truncated appraisals in vocational counseling: Interpreting the interest-efficacy association from a broader perspective: Comment on Armstrong and Vogel (2009).

    Science.gov (United States)

    Lubinski, David

    2010-04-01

    Invited commentary on Armstrong and Vogel's (2009) article on interpreting the interest-efficacy association stimulated an appraisal from a broader perspective. Like empirical research, scale development, and theorizing emanating from social cognitive career theory (SCCT), their conclusion about the importance of assessing both interests and self-efficacy in applied settings and speculations about the developmental sequencing of these attributes need to be evaluated in the context of what decades of longitudinal research reveal are critical determinants of educational and vocational choice, performance after choice, and persistence. For our interventions to be effective and our theory development to be meaningful, we must ensure that innovative measures possess incremental validity relative to cognitive abilities and educational-vocational interests, which are already well established as salient predictors of long-term educational-vocational outcomes. Broader historical, philosophical, and scientific perspectives are provided to enhance practice, research, and theory development. These broader perspectives reveal how well-positioned vocational counseling is for further advances if it builds on (rather than neglects) its longstanding tradition of developing a cumulative psychological science. PsycINFO Database Record (c) 2010 APA, all rights reserved.

  12. Inversion of the Williams syndrome region is a common polymorphism found more frequently in parents of children with Williams syndrome.

    Science.gov (United States)

    Hobart, Holly H; Morris, Colleen A; Mervis, Carolyn B; Pani, Ariel M; Kistler, Doris J; Rios, Cecilia M; Kimberley, Kendra W; Gregg, Ronald G; Bray-Ward, Patricia

    2010-05-15

    Williams syndrome (WS) is a multisystem disorder caused by deletion of about 1.55 Mb of DNA (including 26 genes) on chromosome 7q11.23, a region predisposed to recombination due to its genomic structure. Deletion of the Williams syndrome chromosome region (WSCR) occurs sporadically. To better define chance for familial recurrence and to investigate the prevalence of genomic rearrangements of the region, 257 children with WS and their parents were studied. We determined deletion size in probands by metaphase FISH, parent-of-origin of the deleted chromosome by molecular genetic methods, and inversion status of the WSCR in both parents by interphase FISH. The frequency of WSCR inversion in the transmitting parent group was 24.9%. In contrast, the rate of inversion in the non-transmitting parent group (a reasonable estimate of the rate in the general population) was 5.8%. There were no significant gender differences with respect to parent-of-origin for the deleted chromosome or the incidence of the inversion polymorphism. There was no difference in the rate of spontaneous abortion for mothers heterozygous for the WSCR inversion relative to mothers without the inversion. We calculate that for a parent heterozygous for a WSCR inversion, the chance to have a child with WS is about 1 in 1,750, in contrast to the 1 in 9,500 chance for a parent without an inversion.

  13. 76 FR 13667 - Commercial Furniture Group, Inc., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe...

    Science.gov (United States)

    2011-03-14

    ... Furniture Group, Inc., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe and Thonet, Including...., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe and Thonet, Chicago, IL; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In accordance with Section 223 of...

  14. 77 FR 63308 - J. William Foley Incorporated v. United Illuminating Company; Notice of Complaint

    Science.gov (United States)

    2012-10-16

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-106-000] J. William Foley Incorporated v. United Illuminating Company; Notice of Complaint Take notice that on October 5...) and 825(e), J. William Foley Incorporated (Complainant) filed a formal complaint against United...

  15. A MacWilliams Identity for Convolutional Codes: The General Case

    OpenAIRE

    Gluesing-Luerssen, Heide; Schneider, Gert

    2008-01-01

    A MacWilliams Identity for convolutional codes will be established. It makes use of the weight adjacency matrices of the code and its dual, based on state space realizations (the controller canonical form) of the codes in question. The MacWilliams Identity applies to various notions of duality appearing in the literature on convolutional coding theory.

  16. A MacWilliams Identity for Convolutional Codes : The General Case

    NARCIS (Netherlands)

    Gluesing-Luerssen, Heide; Schneider, Gert

    A MacWilliams Identity for convolutional codes will be established. It makes use of the weight adjacency matrices of the code and its dual, based on state space realizations (the controller canonical form) of the codes in question. The MacWilliams Identity applies to various notions of duality

  17. 33 CFR 164.43 - Automatic Identification System Shipborne Equipment-Prince William Sound.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Automatic Identification System Shipborne Equipment-Prince William Sound. 164.43 Section 164.43 Navigation and Navigable Waters COAST GUARD... Automatic Identification System Shipborne Equipment—Prince William Sound. (a) Until December 31, 2004, each...

  18. Music and Anxiety in Williams Syndrome: A Harmonious or Discordant Relationship?

    Science.gov (United States)

    Dykens, Elisabeth M.; Rosner, Beth A.; Ly, Tran; Sagun, Jaclyn

    2005-01-01

    In this two-part study, we assessed musical involvements in two samples of persons with Williams syndrome compared to others with mental retardation and also related musicality to anxiety and fears in Study 2. Relative to others with mental retardation, those with Williams syndrome were more likely to take music lessons, play an instrument, and…

  19. 33 CFR 167.1701 - In Prince William Sound: Precautionary areas.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false In Prince William Sound: Precautionary areas. 167.1701 Section 167.1701 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1701 In Prince William Sound...

  20. Auditory Attraction: Activation of Visual Cortex by Music and Sound in Williams Syndrome

    Science.gov (United States)

    Thornton-Wells, Tricia A.; Cannistraci, Christopher J.; Anderson, Adam W.; Kim, Chai-Youn; Eapen, Mariam; Gore, John C.; Blake, Randolph; Dykens, Elisabeth M.

    2010-01-01

    Williams syndrome is a genetic neurodevelopmental disorder with a distinctive phenotype, including cognitive-linguistic features, nonsocial anxiety, and a strong attraction to music. We performed functional MRI studies examining brain responses to musical and other types of auditory stimuli in young adults with Williams syndrome and typically…

  1. Anxiety and Repetitive Behaviours in Autism Spectrum Disorders and Williams Syndrome: A Cross-Syndrome Comparison

    Science.gov (United States)

    Rodgers, Jacqui; Riby, Deborah M.; Janes, Emily; Connolly, Brenda; McConachie, Helen

    2012-01-01

    Children with Autism Spectrum Disorder or Williams syndrome are vulnerable to anxiety. The factors that contribute to this risk remain unclear. This study compared anxiety in autism spectrum disorder and Williams Syndrome and examined the relationship between repetitive behaviours and anxiety. Thirty-four children with autism and twenty children…

  2. Intracranial arteries in individuals with the elastin gene hemideletion of Williams syndrome.

    Science.gov (United States)

    Wint, D P; Butman, J A; Masdeu, J C; Meyer-Lindenberg, A; Mervis, C B; Sarpal, D; Morris, C A; Berman, K F

    2014-01-01

    Williams syndrome, a rare genetic disorder with a striking neurobehavioral profile characterized by extreme sociability and impaired visuospatial construction abilities, is caused by a hemideletion that includes the elastin gene, resulting in frequent supravavular aortic stenosis and other stenotic arterial lesions. Strokes have been reported in Williams syndrome. Although the extracranial carotid artery has been studied in a sample of patients with Williams syndrome, proximal intracranial arteries have not. Using MRA, we studied the intracranial vessels in 27 participants: 14 patients with Williams syndrome (age range, 18-44 years; mean age, 27.3 ± 9.1; 43% women) and 13 healthy control participants with similar age and sex distribution (age range, 22-52 years; mean age, 33.4 ± 7.6; 46% women). All participants with Williams syndrome had hemideletions of the elastin gene. Blinded to group allocation or to any other clinical data, a neuroradiologist determined the presence of intracranial vascular changes in the 2 groups. The Williams syndrome group and the healthy control group had similar patency of the proximal intracranial arteries, including the internal carotid and vertebral arteries; basilar artery; and stem and proximal branches of the anterior cerebral artery, MCA, and posterior cerebral arteries. The postcommunicating segment of the anterior cerebral artery was longer in the Williams syndrome group. Despite the elastin haploinsufficiency, the proximal intracranial arteries in Williams syndrome preserve normal patency.

  3. [Vascular malformations in the Williams-Beuren syndrome: report of three new cases].

    Science.gov (United States)

    Sator, Hicham; Rhouni, Fatima Ezzahra; Benjouad, Ibitihale; Rhouni, Fatima Ezzahra; Benjouad, Ibitihale; Dafiri, Rachida; Chat, Latifa

    2016-01-01

    The Williams-Beuren syndrome is a rare genetic disease. It combines classically specific facial dysmorphism, cardiovascular malformations and specific neuropsychological profile. We report three cases of Williams-Beuren syndrome in children with particular emphasis on vascular abnormalities observed on CT angiography and MR angiography.

  4. Brief Report: Developing Spatial Frequency Biases for Face Recognition in Autism and Williams Syndrome

    Science.gov (United States)

    Leonard, Hayley C.; Annaz, Dagmara; Karmiloff-Smith, Annette; Johnson, Mark H.

    2011-01-01

    The current study investigated whether contrasting face recognition abilities in autism and Williams syndrome could be explained by different spatial frequency biases over developmental time. Typically-developing children and groups with Williams syndrome and autism were asked to recognise faces in which low, middle and high spatial frequency…

  5. 78 FR 45515 - Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan...

    Science.gov (United States)

    2013-07-29

    ... DEPARTMENT OF EDUCATION [Docket No.: ED-2013-ICCD-0099] Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan Program Repayment Plan Selection Form AGENCY... notice will be considered public records. Title of Collection: William D. Ford Federal Direct Loan...

  6. 77 FR 58818 - Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal...

    Science.gov (United States)

    2012-09-24

    ... DEPARTMENT OF EDUCATION Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal Direct Loan Program Regulations-- Servicemembers Civil Relief Act SUMMARY: Upon a... in response to this notice will be considered public records. Title of Collection: William D. Ford...

  7. 78 FR 52169 - Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan...

    Science.gov (United States)

    2013-08-22

    ... DEPARTMENT OF EDUCATION [Docket No. ED-2013-ICCD-0109] Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan (Direct Loan) Program Federal Direct PLUS Loan Master... to this notice will be considered public records. Title of Collection: William D. Ford Federal Direct...

  8. High contrast laser marking of alumina

    Science.gov (United States)

    Penide, J.; Quintero, F.; Riveiro, A.; Fernández, A.; del Val, J.; Comesaña, R.; Lusquiños, F.; Pou, J.

    2015-05-01

    Alumina serves as raw material for a broad range of advanced ceramic products. These elements should usually be identified by some characters or symbols printed directly on them. In this sense, laser marking is an efficient, reliable and widely implemented process in industry. However, laser marking of alumina still leads to poor results since the process is not able to produce a dark mark, yielding bad contrast. In this paper, we present an experimental study on the process of marking alumina by three different lasers working in two wavelengths: 1064 nm (Near-infrared) and 532 nm (visible, green radiation). A colorimetric analysis has been carried out in order to compare the resulting marks and its contrast. The most suitable laser operating conditions were also defined and are reported here. Moreover, the physical process of marking by NIR lasers is discussed in detail. Field Emission Scanning Electron Microscopy, High Resolution Transmission Electron Microscopy and X-ray Photoelectron Spectroscopy were also employed to analyze the results. Finally, we propose an explanation for the differences of the coloration induced under different atmospheres and laser parameters. We concluded that the atmosphere is the key parameter, being the inert one the best choice to produce the darkest marks.

  9. Court presentation of bite mark evidence.

    Science.gov (United States)

    Drinnan, A J; Melton, M J

    1985-12-01

    The uniqueness of an individual's bite mark is generally accepted. The use of bite mark analysis to identify or exclude those suspected of crimes is now a well established activity in forensic dentistry. Although the techniques for evaluating bite mark evidence are extremely sophisticated, it is important that the courtroom presentation of such evidence should be as simple as possible and be directed towards those who must judge it. Dentists likely to be involved in the courtroom presentation of bite mark evidence should: be certain that their local law enforcement personnel are frequently updated on the techniques to be used for producing the optimum evidence needed to evaluate bite marks; become acquainted with the current techniques of evaluating bite mark evidence and understand their difficulties and pitfalls; meet with the lawyers (prosecution or defence) before a courtroom appearance, briefing them on the significance of the particular findings; prepare clear and easily understandable visual aids to present to the court the techniques used in the analysis and the bases for the conclusion reached; and offer conclusions derived from the bite mark investigation.

  10. Changing Context of Trade Mark Protection in India: A Review of the Trade Marks Act, 1999

    OpenAIRE

    Pathak, Akhileshwar

    2004-01-01

    With liberalisation and globalisation of the Indian economy, it has become possible for anyone to get into production and services in most of the sectors. This has led to rampant misuse and appropriation of trade marks. In an insulated economy, with monopoly markets, law protecting trade marks had a limited role. In the changed context, however, trade mark law will be a field of much interest for academics and practitioners. Towards this, the paper explores the formation of trade mark law in ...

  11. A new case of keratoconus associated with Williams-Beuren syndrome.

    Science.gov (United States)

    Viana, Melissa Machado; Frasson, Maria; Leão, Letícia Lima; Stofanko, Martin; Gonçalves-Dornelas, Higgor; Cunha, Pricila da Silva; de Aguiar, Marcos José Burle

    2013-09-01

    Williams-Beuren syndrome is a multisystemic genetic disorder caused by a contiguous gene deletion at 7q11.23. Keratoconus is a complex disease and it is suspected to have a genetic origin, although the specific gene responsible for keratoconus has not been identified. Although there are several ocular features in Williams-Beuren syndrome, keratoconus is not regularly described as part of this syndrome. To report a new patient with keratoconus and Williams-Beuren syndrome. This is the third case of an association between Williams-Beuren syndrome and keratoconus. The authors believe that the Williams-Beuren syndrome chromosome region can be a possible target for further investigation as the genetic basis of keratoconus.

  12. Infantile ictal apneas in a child with williams-beuren syndrome.

    Science.gov (United States)

    Myers, Kenneth A; McLeod, D Ross; Bello-Espinosa, Luis

    2013-02-01

    Williams-Beuren syndrome is a genetic disorder rarely associated with seizures. The few described cases of Williams-Beuren syndrome and epilepsy have primarily involved infantile spasms and deletions extending beyond the common deletion region for this disorder. We present the case of a 5-week-old child with ictal apneas and typical Williams-Beuren syndrome deletion. Diagnosis was challenging, because the child had cardiac, respiratory, and gastrointestinal abnormalities typically associated with Williams-Beuren syndrome, which are also associated with cyanotic episodes. The results of interictal electroencephalography were normal, illustrating that prolonged electroencephalography is often essential in evaluation of suspected ictal apneas. Seizure freedom was achieved with carbamazepine. Sudden death is seen in Williams-Beuren syndrome, and this case raises the question whether some of these cases may be related to ictal apneas and could potentially be preventable with appropriate pharmaceutical intervention. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. Elemental marking of arthropod pests in agricultural systems: single and multigenerational marking

    Science.gov (United States)

    Jane Leslie Hayes

    1991-01-01

    Use of elemental markers to study movement of arthropod pests of field crops is reviewed. Trace elements, rubidium (Rb) and cesium (Cs), have provided a nondisruptive method of marking natural adult populations via developmental stage consumption of treated host plants. Multigenerational marking occurs with the transfer of elemental markers from marked adults to...

  14. Syntax in Spanish-speaking children with Williams syndrome.

    Science.gov (United States)

    Benítez-Burraco, Antonio; Garayzábal, Elena; Cuetos, Fernando

    2016-01-01

    The syntactic skills of Spanish-speaking children with Williams syndrome (WS) were assessed in different areas (phrase structure, recursion, and bound anaphora). Children were compared to typically-developing peers matched either in chronological age (CA-TD) or in verbal age (VA-TD). In all tasks children with WS performed significantly worse than CA-TD children, but similarly to VA-TD children. However, significant differences were observed in specific domains, particularly regarding sentences with cross-serial dependencies. At the same time, children with WS were less sensitive to syntactic constraints and exhibited a poorer knowledge of some functional words (specifically, of nonreflexive pronouns). A processing bottleneck or a computational constraint may account for this outcome. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Grammatical gender vs. natural gender in French Williams syndrome.

    Science.gov (United States)

    Ibernon, Laure; Boloh, Yves

    2010-01-01

    This article reports grammatical gender attribution scores in French Williams participants (N=28, mean chronological age=15.1) in an experiment similar to the classic one from Karmiloff-Smith (1979) where grammatical gender was pitted against natural gender. WS participants massively opted for the masculine gender as the default one, just as MA-controls did. They differed from CA-controls, however, in that they provided fewer sex-based responses. Splitting the WS group into two subgroups did not reveal a shift to sex-based responses similar to the one found in controls. It is argued that this latter difference could plausibly be related to differences in cognitive, lexical or meta-linguistic abilities. Copyright © 2010 Elsevier Ltd. All rights reserved.

  16. The Values of Masculinity in William Shakespeare’s Macbeth

    Directory of Open Access Journals (Sweden)

    Mafruha Ferdous

    2017-04-01

    Full Text Available The theme of gender plays a vital role in William Shakespeare’s famous political play Macbeth. From the very beginning of the play the dramatist focuses on the importance of masculinity in gaining power and authority. Lady Macbeth along with the three witches are as important characters as Macbeth. Because they influence Macbeth profoundly. And Shakespeare very carefully draws the character of Lady Macbeth who being a female sometimes exhibits more masculinity than Macbeth. Similarly is the case of the three witches. Though they look like women they are also bearded which prove the presence of masculinity in their nature. Throughout the play several times the exposition of masculinity is demanded from the character of Macbeth. So the value of masculinity plays an important part in the drama.

  17. What motion is: William Neile and the laws of motion.

    Science.gov (United States)

    Kemeny, Max

    2017-07-01

    In 1668-1669 William Neile and John Wallis engaged in a protracted correspondence regarding the nature of motion. Neile was unhappy with the laws of motion that had been established by the Royal Society in three papers published in 1668, deeming them not explanations of motion at all, but mere descriptions. Neile insisted that science could not be informative without a discussion of causes, meaning that Wallis's purely kinematic account of collision could not be complete. Wallis, however, did not consider Neile's objections to his work to be serious. Rather than engage in a discussion of the proper place of natural philosophy in science, Wallis decided to show how Neile's preferred treatment of motion lead to absurd conclusions. This dispute is offered as a case study of dispute resolution within the early Royal Society.

  18. Charles William Lacaillade. Biologist, Parasitologist, Educator, and Mentor.

    Science.gov (United States)

    Imperato, Pascal James

    2017-02-01

    Charles William Lacaillade (1904-1978) was an eminent biologist in the middle decades of the twentieth century. He was born in Lawrence, Massachusetts of parents whose ancestors were French Canadians. His father, also named Charles William Lacaillade, was a dentist who graduated from Tufts University School of Dentistry in 1898. His mother, Elodia Eno, came from a family of very successful businessmen. Lacaillade was the third of six children. His two older brothers, Harold Carleton and Hector Eno, both graduated from the University of Louisville, School of Dentistry, while his younger brother, Lawrence, became a businessman. His sister, Luemma, married Dr. Henry Steadman, a veterinarian, while his youngest sister, Gloria, married a U.S. Army officer, Lieutenant Colonel Victor Anido. Lacaillade received his MS and PhD degrees in biology and zoology from Harvard University. He then became a fellow at The Rockefeller Institute for Medical Research. At both institutions, he studied under some of the most eminent biological scientists of the time. These included Rudolf W. Glaser, George Howard Parker, Theobald Smith, Carl TenBroeck, and William Morton Wheeler. At the Rockefeller Institute, he co-discovered the vector and mode of transmission of Eastern Equine Encephalomyelitis. This discovery, and the research he conducted with Rudolf W. Glaser, quickly established him as an outstanding biological researcher. However, a change in leadership at the Rockefeller Institute resulted in research priorities being given to the disciplines of general physiology, physical chemistry, and nutrition. This shift in the research agenda away from the biological sciences precluded career advancement at the Rockefeller Institute for post-doctoral fellows like Lacaillade. It was the height of the Great Depression, and even biologists with terminal doctoral degrees found it difficult to find positions. In 1935, Lacaillade accepted a position as an assistant in biology at St. John

  19. William Whewell's philosophy of architecture and the historicization of biology.

    Science.gov (United States)

    Quinn, Aleta

    2016-10-01

    William Whewell's work on historical science has received some attention from historians and philosophers of science. Whewell's own work on the history of German Gothic church architecture has been touched on within the context of the history of architecture. To a large extent these discussions have been conducted separately. I argue that Whewell intended his work on Gothic architecture as an attempt to (help) found a science of historical architecture, as an exemplar of historical science. I proceed by analyzing the key features of Whewell's philosophy of historical science. I then show how his architectural history exemplifies this philosophy. Finally, I show how Whewell's philosophy of historical science matches some developments in a science (biological systematics) that, in the mid-to late-nineteenth century, came to be reinterpreted as a historical science. I comment briefly on Whewell as a potential influence on nineteenth century biology and in particular on Darwin. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Punctuation marks activities in two textbook collections of mother tongue (middle school

    Directory of Open Access Journals (Sweden)

    Anderson Cristiano da SILVA

    2016-07-01

    Full Text Available This paper describes the didactic approaches on the punctuation marks found in volumes from 6th to 9th year of two collections: Português: uma proposta para o letramento, by Magda Soares, and Português: linguagens, by William Roberto Cereja and Thereza Cochar Magalhães. In support of our investigation, the research has theoretical framework the contributions of Dialogic Discourse Analysis, taking as input some key concept developed by Bakhtin´s Circle: discourse genres. From the methodological perspective, two axes were proposed: a presentation of the keyword; b description of the discursive enunciation-didactic approaches on the use of punctuation in two collections listed. The results show considerable differences in approach to the punctuation signs of the content between the two collections, which highlight the heterogeneous distribution of content in different grades, and the concentration given to the oral modality in Português: uma proposta para o letramento.

  1. First results from Mark III at SPEAR

    International Nuclear Information System (INIS)

    Einsweiler, K.F.

    The paper presents data on meson decays obtained using the MARK III detector operating at SPEAR. Results on hadronic decays; decays of the etasub(e); and results on radiative decays; are all described. (U.K.)

  2. User's guide : pavement marking management system database.

    Science.gov (United States)

    2011-12-01

    Pavement markings play a critical role in maintaining a safe and efficient driving environment for road users, especially during nighttime conditions. The Texas Department of Transportation (TxDOT) spends millions of dollars each year for installatio...

  3. Mark Twain, Fenimore Cooper, and Batman.

    Science.gov (United States)

    Crick, Robert Alan

    1992-01-01

    Describes how Mark Twain's essay "Fenimore Cooper's Literary Offenses" helped students to get interested in writing and inspired them to write a similar essay critiquing the movie "Batman." Provides excerpts from students' essays. (PRA)

  4. 46 CFR 160.054-6 - Marking.

    Science.gov (United States)

    2010-10-01

    ... “To Close, Press Together Full Length”. The marking may be applied to the container by the silk screen process, using a suitable ink or paint, or may be applied by other means shown to be acceptable. (b...

  5. 49 CFR 180.213 - Requalification markings.

    Science.gov (United States)

    2010-10-01

    ... eddy current examination combined with a visual inspection, the marking is as illustrated in paragraph..., securely affixed in a manner prescribed by the cylinder manufacturer, near the original manufacturer's...

  6. Microscopic saw mark analysis: an empirical approach.

    Science.gov (United States)

    Love, Jennifer C; Derrick, Sharon M; Wiersema, Jason M; Peters, Charles

    2015-01-01

    Microscopic saw mark analysis is a well published and generally accepted qualitative analytical method. However, little research has focused on identifying and mitigating potential sources of error associated with the method. The presented study proposes the use of classification trees and random forest classifiers as an optimal, statistically sound approach to mitigate the potential for error of variability and outcome error in microscopic saw mark analysis. The statistical model was applied to 58 experimental saw marks created with four types of saws. The saw marks were made in fresh human femurs obtained through anatomical gift and were analyzed using a Keyence digital microscope. The statistical approach weighed the variables based on discriminatory value and produced decision trees with an associated outcome error rate of 8.62-17.82%. © 2014 American Academy of Forensic Sciences.

  7. 77 FR 58819 - Notice of Submission for OMB Review; Federal Student Aid; William D. Ford Federal Direct Loan...

    Science.gov (United States)

    2012-09-24

    ... DEPARTMENT OF EDUCATION Notice of Submission for OMB Review; Federal Student Aid; William D. Ford... William D. Ford Federal Direct Loan Program will use this form to request forbearance on their loans when... of Collection: William D. Ford Federal Direct Loan Program General Forbearance Request. OMB Control...

  8. 77 FR 29988 - Notice of Submission for OMB Review; Federal Student Aid; William D. Ford Federal Direct Loan...

    Science.gov (United States)

    2012-05-21

    ... DEPARTMENT OF EDUCATION Notice of Submission for OMB Review; Federal Student Aid; William D. Ford... borrowers in the William D. Ford Federal Direct Loan (Direct Loan) and Federal Family Education Loan (FFEL... of Collection: William D. Ford Federal Direct Loan Program Deferment Request Forms. OMB Control...

  9. Enamel-based mark performance for marking Chinese mystery snail Bellamya chinensis

    Science.gov (United States)

    Wong, Alec; Allen, Craig R.; Hart, Noelle M.; Haak, Danielle M.; Pope, Kevin L.; Smeenk, Nicholas A.; Stephen, Bruce J.; Uden, Daniel R.

    2013-01-01

    The exoskeleton of gastropods provides a convenient surface for carrying marks, and i the interest of improving future marking methods our laboratory assessed the performance of an enamel paint. The endurance of the paint was also compared to other marking methods assessed in the past. We marked the shells of 30 adult Chinese mystery snails Bellamya chinensis and held them in an aquarium for 181 days. We observed no complete degradation of any enamel-paint mark during the 181 days. The enamel-paint mark was superior to a nai;-polish mark, which lasted a median of 100 days. Enamel-paint marks also have a lower rate of loss (0.00 month-1 181 days) than plastic bee tags (0.01 month-1, 57 days), gouache paint (0.07 month-1, 18.5 days), or car body paint from studies found in scientific literature. Legibility of enamel-paint marks had a median lifetime of 102 days. The use of enamel paint on the shells of gastropods is a viable option for studies lasting up to 6 months. Furthermore, visits to capture-mark-recapture site 1 year after application of enamel-paint marks on B. chinesnis shells produced several individuals on which the enamel paint was still visible, although further testing is required to clarify durability over longer periods.

  10. PREOPERATIVE ENDOSCOPIC MARKING OF UNPALPABLE COLONIC TUMORS

    Directory of Open Access Journals (Sweden)

    A. L. Goncharov

    2013-01-01

    Full Text Available The identification of small colon lesions is one of the major problems in laparoscopic colonic resection.Research objective: to develop a technique of visualization of small tumors of a colon by preoperative endoscopic marking of a tumor.Materials and methods. In one day prior to operation to the patient after bowel preparation the colonoscopy is carried out. In the planned point near tumor on antimesentery edge the submucous infiltration of marking solution (Micky Sharpz blue tattoo pigment, UK is made. The volume of entered solution of 1–3 ml. In only 5 months of use of a technique preoperative marking to 14 patients with small (the size of 1–3 cm malignant tumors of the left colon is performed.Results. The tattoo mark was well visualized by during operation at 13 of 14 patients. In all cases we recorded no complications. Time of operation with preoperative marking averaged 108 min, that is significantly less in comparison with average time of operation with an intra-operative colonoscopy – 155 min (р < 0.001.Conclusions. The first experience of preoperative endoscopic marking of non palpable small tumors of a colon is encouraging. Performance of a technique wasn't accompanied by complications and allowed to reduce significantly time of operation and to simplify conditions of performance of operation.

  11. In-Situ Radiological Surveys to Address Nuclear Criticality Safety Requirements During Remediation Activities at the Shallow Land Disposal Area, Armstrong County, Pennsylvania - 12268

    Energy Technology Data Exchange (ETDEWEB)

    Norris, Phillip; Mihalo, Mark; Eberlin, John; Lambert, Mike [Cabrera Services (United States); Matthews, Brian [Nuclear Safety Associates (United States)

    2012-07-01

    Cabrera Services Inc. (CABRERA) is the remedial contractor for the Shallow Land Disposal Area (SLDA) Site in Armstrong County Pennsylvania, a United States (US) Army Corps of Engineers - Buffalo District (USACE) contract. The remediation is being completed under the USACE's Formerly Utilized Sites Remedial Action Program (FUSRAP) which was established to identify, investigate, and clean up or control sites previously used by the Atomic Energy Commission (AEC) and its predecessor, the Manhattan Engineer District (MED). As part of the management of the FUSRAP, the USACE is overseeing investigation and remediation of radiological contamination at the SLDA Site in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), 42 US Code (USC), Section 9601 et. seq, as amended and, the National Oil and Hazardous Substance Pollution Contingency Plan (NCP), Title 40 of the Code of Federal Regulations (CFR) Section 300.430(f) (2). The objective of this project is to clean up radioactive waste at SLDA. The radioactive waste contains special nuclear material (SNM), primarily U-235, in 10 burial trenches, Cabrera duties include processing, packaging and transporting the waste to an offsite disposal facility in accordance with the selected remedial alternative as defined in the Final Record of Decision (USACE, 2007). Of particular importance during the remediation is the need to address nuclear criticality safety (NCS) controls for the safe exhumation and management of waste containing fissile materials. The partnership between Cabrera Services, Inc. and Measutronics Corporation led to the development of a valuable survey tool and operating procedure that are essential components of the SLDA Criticality Safety and Material Control and Accountability programs. Using proven existing technologies in the design and manufacture of the Mobile Survey Cart, the continued deployment of the Cart will allow for an efficient and reliable

  12. Leftward lateralization of auditory cortex underlies holistic sound perception in Williams syndrome.

    Directory of Open Access Journals (Sweden)

    Martina Wengenroth

    Full Text Available BACKGROUND: Individuals with the rare genetic disorder Williams-Beuren syndrome (WS are known for their characteristic auditory phenotype including strong affinity to music and sounds. In this work we attempted to pinpoint a neural substrate for the characteristic musicality in WS individuals by studying the structure-function relationship of their auditory cortex. Since WS subjects had only minor musical training due to psychomotor constraints we hypothesized that any changes compared to the control group would reflect the contribution of genetic factors to auditory processing and musicality. METHODOLOGY/PRINCIPAL FINDINGS: Using psychoacoustics, magnetoencephalography and magnetic resonance imaging, we show that WS individuals exhibit extreme and almost exclusive holistic sound perception, which stands in marked contrast to the even distribution of this trait in the general population. Functionally, this was reflected by increased amplitudes of left auditory evoked fields. On the structural level, volume of the left auditory cortex was 2.2-fold increased in WS subjects as compared to control subjects. Equivalent volumes of the auditory cortex have been previously reported for professional musicians. CONCLUSIONS/SIGNIFICANCE: There has been an ongoing debate in the neuroscience community as to whether increased gray matter of the auditory cortex in musicians is attributable to the amount of training or innate disposition. In this study musical education of WS subjects was negligible and control subjects were carefully matched for this parameter. Therefore our results not only unravel the neural substrate for this particular auditory phenotype, but in addition propose WS as a unique genetic model for training-independent auditory system properties.

  13. Oxytocin and vasopressin are dysregulated in Williams Syndrome, a genetic disorder affecting social behavior.

    Directory of Open Access Journals (Sweden)

    Li Dai

    Full Text Available The molecular and neural mechanisms regulating human social-emotional behaviors are fundamentally important but largely unknown; unraveling these requires a genetic systems neuroscience analysis of human models. Williams Syndrome (WS, a condition caused by deletion of ~28 genes, is associated with a gregarious personality, strong drive to approach strangers, difficult peer interactions, and attraction to music. WS provides a unique opportunity to identify endogenous human gene-behavior mechanisms. Social neuropeptides including oxytocin (OT and arginine vasopressin (AVP regulate reproductive and social behaviors in mammals, and we reasoned that these might mediate the features of WS. Here we established blood levels of OT and AVP in WS and controls at baseline, and at multiple timepoints following a positive emotional intervention (music, and a negative physical stressor (cold. We also related these levels to standardized indices of social behavior. Results revealed significantly higher median levels of OT in WS versus controls at baseline, with a less marked increase in AVP. Further, in WS, OT and AVP increased in response to music and to cold, with greater variability and an amplified peak release compared to controls. In WS, baseline OT but not AVP, was correlated positively with approach, but negatively with adaptive social behaviors. These results indicate that WS deleted genes perturb hypothalamic-pituitary release not only of OT but also of AVP, implicating more complex neuropeptide circuitry for WS features and providing evidence for their roles in endogenous regulation of human social behavior. The data suggest a possible biological basis for amygdalar involvement, for increased anxiety, and for the paradox of increased approach but poor social relationships in WS. They also offer insight for translating genetic and neuroendocrine knowledge into treatments for disorders of social behavior.

  14. Williams-Beuren syndrome associated with single kidney and nephrocalcinosis: a case report.

    Science.gov (United States)

    Abidi, Kamel; Jellouli, Manel; Ben Rabeh, Rania; Hammi, Yousra; Gargah, Tahar

    2015-01-01

    Williams-Beuren syndrome is a rare neurodevelopmental disorder, characterized by congenital heart defects, abnormal facial features, mental retardation with specific cognitive and behavioral profile, growth hormone deficiency, renal and skeletal anomalies, inguinal hernia, infantile hypercalcaemia. We report a case with Williams-Beuren syndrome associated with a single kidney and nephrocalcinosis complicated by hypercalcaemia. A male infant, aged 20 months presented growth retardation associated with a psychomotor impairment, dysmorphic features and nephrocalcinosis. He had also hypercalciuria and hypercalcemia. Echocardiography was normal. DMSA renal scintigraphy showed a single functioning kidney. The FISH generated one ELN signal in 20 metaphases read and found the presence of ELN deletion, with compatible Williams-Beuren syndrome.

  15. Forensic surface metrology: tool mark evidence.

    Science.gov (United States)

    Gambino, Carol; McLaughlin, Patrick; Kuo, Loretta; Kammerman, Frani; Shenkin, Peter; Diaczuk, Peter; Petraco, Nicholas; Hamby, James; Petraco, Nicholas D K

    2011-01-01

    Over the last several decades, forensic examiners of impression evidence have come under scrutiny in the courtroom due to analysis methods that rely heavily on subjective morphological comparisons. Currently, there is no universally accepted system that generates numerical data to independently corroborate visual comparisons. Our research attempts to develop such a system for tool mark evidence, proposing a methodology that objectively evaluates the association of striated tool marks with the tools that generated them. In our study, 58 primer shear marks on 9 mm cartridge cases, fired from four Glock model 19 pistols, were collected using high-resolution white light confocal microscopy. The resulting three-dimensional surface topographies were filtered to extract all "waviness surfaces"-the essential "line" information that firearm and tool mark examiners view under a microscope. Extracted waviness profiles were processed with principal component analysis (PCA) for dimension reduction. Support vector machines (SVM) were used to make the profile-gun associations, and conformal prediction theory (CPT) for establishing confidence levels. At the 95% confidence level, CPT coupled with PCA-SVM yielded an empirical error rate of 3.5%. Complementary, bootstrap-based computations for estimated error rates were 0%, indicating that the error rate for the algorithmic procedure is likely to remain low on larger data sets. Finally, suggestions are made for practical courtroom application of CPT for assigning levels of confidence to SVM identifications of tool marks recorded with confocal microscopy. Copyright © 2011 Wiley Periodicals, Inc.

  16. Mark 4A project training evaluation

    Science.gov (United States)

    Stephenson, S. N.

    1985-11-01

    A participant evaluation of a Deep Space Network (DSN) is described. The Mark IVA project is an implementation to upgrade the tracking and data acquisition systems of the dSN. Approximately six hundred DSN operations and engineering maintenance personnel were surveyed. The survey obtained a convenience sample including trained people within the population in order to learn what training had taken place and to what effect. The survey questionnaire used modifications of standard rating scales to evaluate over one hundred items in four training dimensions. The scope of the evaluation included Mark IVA vendor training, a systems familiarization training seminar, engineering training classes, a on-the-job training. Measures of central tendency were made from participant rating responses. Chi square tests of statistical significance were performed on the data. The evaluation results indicated that the effects of different Mark INA training methods could be measured according to certain ratings of technical training effectiveness, and that the Mark IVA technical training has exhibited positive effects on the abilities of DSN personnel to operate and maintain new Mark IVA equipment systems.

  17. Mark 4A project training evaluation

    Science.gov (United States)

    Stephenson, S. N.

    1985-01-01

    A participant evaluation of a Deep Space Network (DSN) is described. The Mark IVA project is an implementation to upgrade the tracking and data acquisition systems of the dSN. Approximately six hundred DSN operations and engineering maintenance personnel were surveyed. The survey obtained a convenience sample including trained people within the population in order to learn what training had taken place and to what effect. The survey questionnaire used modifications of standard rating scales to evaluate over one hundred items in four training dimensions. The scope of the evaluation included Mark IVA vendor training, a systems familiarization training seminar, engineering training classes, a on-the-job training. Measures of central tendency were made from participant rating responses. Chi square tests of statistical significance were performed on the data. The evaluation results indicated that the effects of different Mark INA training methods could be measured according to certain ratings of technical training effectiveness, and that the Mark IVA technical training has exhibited positive effects on the abilities of DSN personnel to operate and maintain new Mark IVA equipment systems.

  18. Neurosurgeon as innovator: William V. Cone (1897-1959).

    Science.gov (United States)

    Preul, M C; Stratford, J; Bertrand, G; Feindel, W

    1993-10-01

    Neurosurgeons are well known for being productive researchers and innovators. Few, however, have possessed the prolific ingenuity of William Cone. In 1934, he and William Penfield were cofounders of the Montreal Neurological Institute where, until 1959, he filled the twin roles of neurosurgeon-in-chief and neuropathologist. Because he did not find writing easy, many of his technical inventions and refinements remained unpublished. His numerous innovations included the extensive use of twist-drill technique for biopsy, drainage for subdural hematoma and cerebral abscess, and ventriculography. In the mid-1940's, he developed power tools driven by nitrogen that led to the modern, universally used air-driven tool systems. He had a special interest in the treatment of spinal dysfunction, for which he invented the Cone-Barton skull-traction tongs along with the Cone spinal operating table. He also devised operative procedures for vertebral fracture-dislocation and craniospinal anomalies. For the maintenance of muscle tone in the paralyzed bladder, he constructed a tidal drainage system. He introduced and popularized ventriculoperitoneal shunting techniques and carried out some of the earliest experimental trails to treat brain infections with sulphonamide and antibiotic drugs. He designed his own set of surgical suction devices, bone rongeurs, and a personal suction "air-conditioning" system for each surgeon. He had a keen early interest in intracranial tumors, and also demonstrated on monkeys how subdural mass lesions caused pupillary dilation and mesial temporal lobe damage due to cerebral compression. His work for the military during World War II on effects of altitude on brain pressure remained classified for many years. The first clipping and excision of an intracranial aneurysm is attributed to Cone. Although Penfield was known as "the Chief," Cone was referred to as "the Boss." His fervent dedication to provide total care to his patients was expressed in round

  19. Early Science Results from the Williams College Eclipse Expedition

    Science.gov (United States)

    Pasachoff, Jay M.; Person, Michael J.; Dantowitz, Ron; Lockwood, Christian A.; Nagle-McNaughton, Tim; Meadors, Erin N.; Perez, Cielo C.; Marti, Connor J.; Yu, Ross; Rosseau, Brendan; Daly, Declan M.; Ide, Charles A.; Davis, Allen B.; Lu, Muzhou; Sliski, David; Seiradakis, John; Voulgaris, Aris; Rusin, Vojtech; Peñaloza-Murillo, Marcos A.; Roman, Michael; Seaton, Daniel B.; Steele, Amy; Lee, Duane M.; Freeman, Marcus J.

    2018-01-01

    We describe our first cut of data reduction on a wide variety of observations of the solar corona and of the effect of the penumbra and umbra on the terrestrial atmosphere, carried out from our eclipse site on the campus of Willamette University in Salem, Oregon. Our team of faculty, undergraduate students, graduate students, and other colleagues observed the eclipse, taking images and spectra with a variety of sensors and telescopes. Equipment included frame-transfer cameras observing at 3 Hz in 0.3 nm filters at the coronal green and red lines to measure the power spectrum of oscillations in coronal loops or elsewhere in the lower corona; 3 spectrographs; a variety of telescopes and telephotos for white-light imaging; a double Lyot system tuned at Fe XIV 530.3 nm (FWHM 0.4 nm) and Fe X 637.4 nm (FWHM 0.5 nm); and a weather station to record changes in the terrestrial atmosphere. We are comparing our observations with predictions based on the previous mapping of the photospheric magnetic field, and preparing wide-field complete coronal imaging incorporating NOAA/NASA GOES-16 SUVI and NRL/NASA/LASCO for the corona outside our own images (which extend, given the completely clear skies we had, at least 4 solar radii), and NASA SDO/AIA and NOAA/NASA GOES-16 SUVI for the solar disk. One of our early composites appeared as Astronomy Picture of the Day for September 27: https://apod.nasa.gov/apod/ap170927.htmlOur expedition was supported in large part by grants from the Committee for Research and Exploration of the National Geographic Society and from the Solar Terrestrial Program of the Atmospheric and Geospace Sciences Division of the National Science Foundation, with additional student support from the STP/AGS of NSF, the NASA Massachusetts Space Grant Consortium, the Sigma Xi honorary scientific society, the Clare Booth Luce Foundation studentship and the Freeman Foote Expeditionary Fund at Williams College, other Williams College funds, and U. Pennsylvania funds.

  20. The national hydrologic bench-mark network

    Science.gov (United States)

    Cobb, Ernest D.; Biesecker, J.E.

    1971-01-01

    The United States is undergoing a dramatic growth of population and demands on its natural resources. The effects are widespread and often produce significant alterations of the environment. The hydrologic bench-mark network was established to provide data on stream basins which are little affected by these changes. The network is made up of selected stream basins which are not expected to be significantly altered by man. Data obtained from these basins can be used to document natural changes in hydrologic characteristics with time, to provide a better understanding of the hydrologic structure of natural basins, and to provide a comparative base for studying the effects of man on the hydrologic environment. There are 57 bench-mark basins in 37 States. These basins are in areas having a wide variety of climate and topography. The bench-mark basins and the types of data collected in the basins are described.

  1. The Mark II Vertex Drift Chamber

    International Nuclear Information System (INIS)

    Alexander, J.P.; Baggs, R.; Fujino, D.

    1989-03-01

    We have completed constructing and begun operating the Mark II Drift Chamber Vertex Detector. The chamber, based on a modified jet cell design, achieves 30 μm spatial resolution and 2 gas mixtures. Special emphasis has been placed on controlling systematic errors including the use of novel construction techniques which permit accurate wire placement. Chamber performance has been studied with cosmic ray tracks collected with the chamber located both inside and outside the Mark II. Results on spatial resolution, average pulse shape, and some properties of CO 2 mixtures are presented. 10 refs., 12 figs., 1 tab

  2. THE MARK I BUSINESS SYSTEM SIMULATION MODEL

    Science.gov (United States)

    of a large-scale business simulation model as a vehicle for doing research in management controls. The major results of the program were the...development of the Mark I business simulation model and the Simulation Package (SIMPAC). SIMPAC is a method and set of programs facilitating the construction...of large simulation models. The object of this document is to describe the Mark I Corporation model, state why parts of the business were modeled as they were, and indicate the research applications of the model. (Author)

  3. William Basse’s Polyhymnia and the Poetry of Service

    Directory of Open Access Journals (Sweden)

    Ben Crabstick

    2015-03-01

    Full Text Available The career of the little-known seventeenth-century poet William Basse (c. 1583-1653? combined two distinctive elements. He served, in the first instance, as a ‘retainer’ to the Wenman family of Thame Park in Oxfordshire for a period of more than forty years. He was also, however, a published poet who produced a substantial body of verse which reflected and intertwined with his career in service. The article aims to stimulate interest in Basse by drawing attention to a manuscript collection of his poems which remains unpublished and has until now been considered ‘lost’ in scholarly accounts of the poet. The Polyhymnia, held at Chetham’s Library in Manchester, was prepared as a gift in the late 1640s or early 1650s for relations of the Wenmans who lived on the nearby Rycote estate. It brought together poems from across the course of Basse’s career, and displayed him writing in a wide variety of forms and genres. The article summarises current knowledge of Basse’s life in service, sets out the context of the Polyhymnia as a manuscript apparently designed to fortify the links between Thame Park and Rycote, and explores the importance of Basse’s perspective as a servant to some of the more intriguing poems in the collection. It concludes by suggesting some of the ways in which a renewed focus upon Basse might contribute to study of the links between service and literature in the future.

  4. William Nierenberg: blockbuster. [Recommendations as alternative or substitution fuel

    Energy Technology Data Exchange (ETDEWEB)

    1977-12-01

    An interview with William Nierenberg, Univ. of California, Berkeley and Scripps Institution of Oceanography, elicits the physicist/environmentalist's determination to expedite the application of available technical solutions. His success in penetrating social and institutional barriers is evidenced by his efforts to have methanol accepted as a substitute fuel. Perceiving these barriers as more formidable than the task of finding technological answers to energy problems, he elaborates on the case for methanol, which is widely used in Europe and does not require large investments for research and development. As a clean-burning substitute for low-sulfur oil, methanol's only drawback as a utility fuel has been price. However, he estimates that large-scale production of methanol will make it competitive with other fuels. He also recommends pursuing solar and ocean thermal energy. As a member of EPRI's Advisory Council, his approach to legislation balances environmental concerns with an understanding of practical issues. (DCK)

  5. Introduction to William Stephenson's quest for a science of subjectivity.

    Science.gov (United States)

    Good, James M M

    2010-01-01

    In this introduction to the life and work of William Stephenson my aim is to provide a general overview of the development of his thinking and, more specifically, to highlight the importance he attached to the study of single cases. I also attempt to provide a context for an understanding of the significance of his "Tribute to Melanie Klein." Some of the principal reasons for Stephenson's marginal status in the discipline of psychology will also emerge in the course of the article. I begin by outlining some of the central notions in Q-methodology. The early sections of the article trace his roots in the north of England - the setting for his schooling and university training in physics - and then outline his encounters with Charles Spearman and Cyril Burt at University College London. The subsequent section deals with his time at the University of Oxford Institute of Experimental Psychology and the wartime interruption to his career. The next few sections take us across the Atlantic and describe some of the most significant features of his work on Q-methodology. these sections also record the difficulties Stephenson experienced before he eventually secured a tenured position at the University of Missouri School of Journalism in Columbia. In the final section I attempt to situate Q-methodology in relation to some of the principal theoretical orientations in the human sciences.

  6. In Search of William Gascoigne Seventeenth Century Astronomer

    CERN Document Server

    Sellers, David

    2012-01-01

    William Gascoigne (c.1612-44), the first inventor of the telescopic sight and micrometer—instruments crucial to the advance of astronomy—was killed in the English Civil War. His name is now known to historians of science around the world, but for some considerable time after his tragic death at the age of 32, it seemed as if his achievements would be consigned to oblivion. Most of his papers were lost in the maelstrom of war and the few that seemed to have survived later disappeared. This is the story of how his work was rescued. Woven into that story is an account of the state of astronomy and optics during Gascoigne’s lifetime, so that the reader can appreciate the significance of his discoveries.   A substantial appendix presents selected extracts from Gascoigne's correspondence. This includes much new material that has not been previously published and illustrates his efforts to explain the basis of his pioneering techniques to the satisfaction of his contemporaries.   

  7. Capacity to improve fine motor skills in Williams syndrome.

    Science.gov (United States)

    Berencsi, A; Gombos, F; Kovács, I

    2016-10-01

    Individuals with Williams syndrome (WS) are known to have difficulties in carrying out fine motor movements; however, a detailed behavioural profile of WS in this domain is still missing. It is also unknown how great the capacity to improve these skills with focused and extensive practice is. We studied initial performance and learning capacity in a sequential finger tapping (FT) task in WS and in typical development. Improvement in the FT task has been shown to be sleep dependent. WS subjects participating in the current study have also participated in earlier polysomnography studies, although not directly related to learning. WS participants presented with great individual variability. In addition to generally poor initial performance, learning capacity was also greatly limited in WS. We found indications that reduced sleep efficiency might contribute to this limitation. Estimating motor learning capacity and the depth of sleep disorder in a larger sample of WS individuals might reveal important relationships between sleep and learning, and contribute to efficient intervention methods improving skill acquisition in WS. © 2016 The Authors. Journal of Intellectual Disability Research published by MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  8. Perceptual learning in Williams syndrome: looking beyond averages.

    Directory of Open Access Journals (Sweden)

    Patricia Gervan

    Full Text Available Williams Syndrome is a genetically determined neurodevelopmental disorder characterized by an uneven cognitive profile and surprisingly large neurobehavioral differences among individuals. Previous studies have already shown different forms of memory deficiencies and learning difficulties in WS. Here we studied the capacity of WS subjects to improve their performance in a basic visual task. We employed a contour integration paradigm that addresses occipital visual function, and analyzed the initial (i.e. baseline and after-learning performance of WS individuals. Instead of pooling the very inhomogeneous results of WS subjects together, we evaluated individual performance by expressing it in terms of the deviation from the average performance of the group of typically developing subjects of similar age. This approach helped us to reveal information about the possible origins of poor performance of WS subjects in contour integration. Although the majority of WS individuals showed both reduced baseline and reduced learning performance, individual analysis also revealed a dissociation between baseline and learning capacity in several WS subjects. In spite of impaired initial contour integration performance, some WS individuals presented learning capacity comparable to learning in the typically developing population, and vice versa, poor learning was also observed in subjects with high initial performance levels. These data indicate a dissociation between factors determining initial performance and perceptual learning.

  9. Narrative competence in Spanish-speaking adults with Williams syndrome.

    Science.gov (United States)

    Diez-Itza, Eliseo; Martínez, Verónica; Antón, Aránzazu

    2016-08-01

    Williams syndrome (WS) is a genetic disorder associated with intellectual disability and characterised by displaying an atypical neuropsychological profile, with peaks and valleys, where language skills seem better preserved than non-verbal intelligence. This study researches the narrative competence of nine Spanish-speaking adults with WS. Oral narratives were elicited from a silent film, and narrative coherence was analysed as a function of sequential order of the events narrated at three structure levels, while narrative cohesion was assessed through the frequency of use and type of discourse markers. WS subjects were able to remember a significant proportion of the events from the film, but coherence of narratives, i.e., sequential order of events, was more impaired. Consistently with their linguistic abilities, cohesion of narratives was better preserved, as they used discourse markers to introduce a high proportion of events. Construction of mental models of the narratives may be constrained in WS by non-verbal cognitive abilities, but narrative competence is also determined by textual pragmatic abilities to organize discourse, which should be addressed by specific intervention in narrative competence.

  10. Auditory cortical volumes and musical ability in Williams syndrome.

    Science.gov (United States)

    Martens, Marilee A; Reutens, David C; Wilson, Sarah J

    2010-07-01

    Individuals with Williams syndrome (WS) have been shown to have atypical morphology in the auditory cortex, an area associated with aspects of musicality. Some individuals with WS have demonstrated specific musical abilities, despite intellectual delays. Primary auditory cortex and planum temporale volumes were manually segmented in 25 individuals with WS and 25 control participants, and the participants also underwent testing of musical abilities. Left and right planum temporale volumes were significantly larger in the participants with WS than in controls, with no significant difference noted between groups in planum temporale asymmetry or primary auditory cortical volumes. Left planum temporale volume was significantly increased in a subgroup of the participants with WS who demonstrated specific musical strengths, as compared to the remaining WS participants, and was highly correlated with scores on a musical task. These findings suggest that differences in musical ability within WS may be in part associated with variability in the left auditory cortical region, providing further evidence of cognitive and neuroanatomical heterogeneity within this syndrome. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  11. THE SYNTACTICAL ABILITY OF A YOUNG GIRL WITH WILLIAMS SYNDROME

    Directory of Open Access Journals (Sweden)

    Diana ARAPOVIKJ

    2008-06-01

    Full Text Available This research was carried out on a young girl with Williams syndrome, whose syntactical ability was tested longitudinally over a period of 22 months, from age 9 years and 3 months to 11 years and 1 month. The assumption was that the girl with Wil­liams syndrome would have poorer syntactical ability than children with regular development, but similar to children with specific language impair­ment (SLI and that in all tasks she would achieve better results in the final testing. Syntax was ana­lyzed on the basis of the fundamental variable of repeating sentences, which consisted of five sub-variables: literal repetition of sentences, sentences repeated with omissions, ungrammatical repetition of sentences, sentences with altered content, sen­tences not repeated. A statistical difference was found between the syntactical ability of the girl with Williams’ syndrome and children with normal development in all tested sub-variables, and her results were the same as in children with specific language impairment. Moreover, in the final test­ing the girl achieved better results than in the ini­tial test.

  12. Addressing social skills deficits in adults with Williams syndrome.

    Science.gov (United States)

    Fisher, Marisa H; Morin, Lindsay

    2017-12-01

    Individuals with Williams syndrome (WS) are hypersocial; yet, they experience social difficulties and trouble with relationships. This report summarizes findings from three studies examining the social functioning of adults with WS and the feasibility of a social skills training program for adults with WS (SSTP-WS) through the examination of performance on initial lesson plans. Study 1: 114 parents of adults with WS completed the Social Responsiveness Scale-2. Study 2: 10 adults with WS and 12 of their parents participated in focus groups to further describe the deficits identified in Study 1 and to discuss a SSTP-WS. Study 3: 30 adults with WS were randomly assigned to 2 lessons on either conversations or relationships and pre-post change in social skills knowledge was assessed. Study 1 indicates adults with WS experience severe social impairments in social cognition, and mild-moderate impairments in social awareness and social communication. Qualitative results in Study 2 indicate a SSTP-WS should address conversation skills and relationships. In Study 3, participants showed gains in social skills knowledge following completion of lessons. A SSTP-WS may be beneficial for adults with WS. Future research should describe the social needs of individuals with WS at different ages and should further develop a SSTP-WS. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Hydrographic trends in Prince William Sound, Alaska, 1960-2016

    Science.gov (United States)

    Campbell, Robert W.

    2018-01-01

    A five-decade time series of temperature and salinity profiles within Prince William Sound (PWS) and the immediately adjacent shelf was assembled from several archives and ongoing field programs, and augmented with archived SST observations. Observations matched with recent cool (2007-2013) and warm (2013-onward) periods in the region, and also showed an overall regional warming trend ( 0.1 to 0.2 °C decade-1) that matched long-term increases in heat transport to the surface ocean. A cooling and freshening trend ( - 0.2 °C decade-1 and 0.02 respectively) occurred in the near surface waters in some portions of PWS, particularly the northwestern margin, which is also the location of most of the ice mass in the region; discharge (estimated from other studies) has increased over time, suggesting that those patterns were due to increased meltwater inputs. Increases in salinity at depth were consistent with enhanced entrainment of deep water by estuarine circulations, and by enhanced deep water renewal caused by reductions in downwelling-favorable winds. As well as local-scale effects, temperature and salinity were positively cross correlated with large scale climate and lunar indexes at long lags (years to months), indicating the longer time scales of atmospheric and transport connections with the Gulf of Alaska. Estimates of mixed layer depths show a shoaling of the seasonal mixed layer over time by several meters, which may have implications for ecosystem productivity in the region.

  14. Edouard Glissant e o legado de William Faulkner

    Directory of Open Access Journals (Sweden)

    Eurídice Figueiredo

    2011-11-01

    Full Text Available Este trabajo se propone analizar el intertexto que une al escritor Edouard Glissant con William Faulkner a través de dos obras: el ensayo Faulkner, Mississipi [1996] y la novela Sartorius [1999]. En el primer texto, el autor enfatiza cuestiones presentes en su propia obra novelesca: la genealogía, la relación con el espacio de la plantación, el mestizaje, la [i]legitimidad de derechos con respecto a la posesión de la tierra, la opacidad. En el segundo, traza una línea genealógica de un personaje perteneciente a una etnia africana imaginaria, haciéndolo llegar hasta las plantaciones del sur de los Estados Unidos; paralelamente, presenta la línea genealógica de los Sartoris. En esta dirección, busco mostrar cómo el proyecto literario de Glissant dialoga con la obra de Faulkner, indagando e inventariando las mismas problemáticas con respecto al transplante de poblaciones y su inserción en el espacio de las plantaciones, tanto en el sur de los Estados Unidos como en las islas del Caribe. En las obras de ambos escritores puede percibirse el mismo vértigo trágico que persigue a los personajes, conduciéndolos a la locura, el sufrimiento y la muerte

  15. Facilitating complex shape drawing in Williams syndrome and typical development.

    Science.gov (United States)

    Hudson, Kerry D; Farran, Emily K

    2013-07-01

    Individuals with Williams syndrome (WS) produce drawings that are disorganised, likely due to an inability to replicate numerous spatial relations between parts. This study attempted to circumvent these drawing deficits in WS when copying complex combinations of one, two and three shapes. Drawing decisions were reduced by introducing a number of facilitators, for example, by using distinct colours and including facilitatory cues on the response sheet. Overall, facilitation improved drawing in the WS group to a comparable level of accuracy as typically developing participants (matched for non-verbal ability). Drawing accuracy was greatest in both groups when planning demands (e.g. starting location, line lengths and changes in direction) were reduced by use of coloured figures and providing easily distinguished and clearly grouped facilitatory cues to form each shape. This study provides the first encouraging evidence to suggest that drawing of complex shapes in WS can be facilitated; individuals with WS might be receptive to remediation programmes for drawing and handwriting. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. English Medieval Churches, 'Festival Orientation' and William Wordsworth

    Science.gov (United States)

    Hoare, Peter G.; Ketel, Hans

    2015-05-01

    A church that is shown to be aligned with sunrise or sunset on the feast day of the saint to whom the building was dedicated is said to display 'festival orientation'. The earliest work to touch upon this practice in English dates from c. 1678. William Wordsworth gave impetus to the subject in two poems published in 1827; he also played a part in the design of St Mary's chapel (1823-4), Rydal, Cumbria in the English Lake District. The 14th-century St Catherine's chapel at Houghton St Giles, Norfolk, was constructed for the use of pilgrims on their way to nearby Walsingham. Careful measurement of the orientation and eastern horizon of these two buildings has shown that St Mary's is aligned with sunrise on the Marian festival of The Visitation (2 July), and St Catherine's is directed towards the rising Sun on the feast of St Catherine of Alexandria (25 November). It is only by taking into account the character of the horizon that meaningful tests for festival orientation may be carried out.

  17. William Henry Broadbent (1835-1907) as a neurologist.

    Science.gov (United States)

    Eadie, Mervyn

    2015-01-01

    By the end of his career, Sir William Broadbent (1835-1907) had become an eminent London general physician who had been appointed Physician-in-Ordinary to King Edward VII and to the Prince of Wales. Previously he had been Physician-in-Extraordinary to Queen Victoria. At earlier stages in his professional life, he had played a significant role in the development of clinical neurology in Victorian-era Britain. In 1866, he had enunciated a principle (Broadbent's hypothesis) that for the first time satisfactorily accounted for the mechanisms by which the trunk and bulbar muscles and the upper face were spared in hemiplegia. He had also carried out original investigations into the distribution of fiber tracts in the human cerebral hemispheres. At intervals over the years, he published on aspects of aphasia and developed a rather complicated though logical conceptual schema of the presumed anatomical background to the process of speech, based on clinic-pathological correlations. His role in all this neurological research and his other contributions on subjects such as neurosyphilis have largely been forgotten by subsequent generations.

  18. Lord Byron's physician: John William Polidori on somnambulism.

    Science.gov (United States)

    Finger, Stanley; Stiles, Anne

    2013-01-01

    John William Polidori (1795-1821) was the Edinburgh-trained physician hired by Lord Byron to accompany him to Switzerland, where he participated in the story-telling event proposed by Byron that led, with Polidori's help, to Mary Shelley's Frankenstein. Although those interested in English literature might also remember Polidori as the author of The Vampyre, one of the first extended works of fiction about vampires, his earlier interest in somnambulism and trance states is only beginning to be appreciated. Even more than students of Romantic literature, historians of science and medicine seem little aware of what Polidori had written about oneirodynia, a synonym for somnambulism, and how his thoughts from 1815 about such activities reflected the changing medical zeitgeist at this time. This chapter examines Polidori's medical thesis in a neuroscience context and compares what he wrote to the writings of several other physicians who were fascinated by nocturnal wanderings, their causes, their manifestations, and their possible treatments. © 2013 Elsevier B.V. All rights reserved.

  19. Predictors of specific phobia in children with Williams syndrome.

    Science.gov (United States)

    Pitts, C H; Klein-Tasman, B P; Osborne, J W; Mervis, C B

    2016-10-01

    Specific phobia (SP) is the most common anxiety disorder among children with Williams syndrome (WS); prevalence rates derived from Diagnostic and Statistical Manual of Mental Disorders-based diagnostic interviews range from 37% to 56%. We evaluated the effects of gender, age, intellectual abilities and/or behaviour regulation difficulties on the likelihood that a child with WS would be diagnosed with SP. A total of 194 6-17 year-olds with WS were evaluated. To best characterise the relations between the predictors and the probability of a SP diagnosis, we explored not only possible linear effects but also curvilinear effects. No gender differences were detected. As age increased, the likelihood of receiving a SP diagnosis decreased. As IQ increased, the probability of receiving a SP diagnosis also decreased. Behaviour regulation difficulties were the strongest predictor of a positive diagnosis. A quadratic relation was detected: The probability of receiving a SP diagnosis gradually rose as behaviour regulation difficulties increased. However, once behaviour regulation difficulties approached the clinical range, the probability of receiving a SP diagnosis asymptoted at a high level. Children with behaviour regulation difficulties in or just below the clinical range were at the greatest risk of developing SP. These findings highlight the value of large samples and the importance of evaluating for nonlinear effects to provide accurate model specification when characterising relations among a dependent variable and possible predictors. © 2016 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  20. Musical learning in children and adults with Williams syndrome.

    Science.gov (United States)

    Lense, M; Dykens, E

    2013-09-01

    There is recent interest in using music making as an empirically supported intervention for various neurodevelopmental disorders due to music's engagement of perceptual-motor mapping processes. However, little is known about music learning in populations with developmental disabilities. Williams syndrome (WS) is a neurodevelopmental genetic disorder whose characteristic auditory strengths and visual-spatial weaknesses map onto the processes used to learn to play a musical instrument. We identified correlates of novel musical instrument learning in WS by teaching 46 children and adults (7-49 years) with WS to play the Appalachian dulcimer. Obtained dulcimer skill was associated with prior musical abilities (r = 0.634, P learning strategies, but not visual or instructional strategies, predicted greater dulcimer skill beyond individual musical and visual-motor integration abilities (β = 0.285, sr(2) = 0.06, P = 0.019). These findings map onto behavioural and emerging neural evidence for greater auditory-motor mapping processes in WS. Results suggest that explicit awareness of task-specific learning approaches is important when learning a new skill. Implications for using music with populations with syndrome-specific strengths and weakness will be discussed. © 2012 The Authors. Journal of Intellectual Disability Research © 2012 John Wiley & Sons Ltd, MENCAP & IASSID.

  1. THE HISTORY OF DESIGN EDUCATION AND WILLIAM MORRIS

    Directory of Open Access Journals (Sweden)

    Oguz DILMAC

    2015-04-01

    Full Text Available Industrial revolution had an impact on art as well as other fields of society in the years 1760-1860. The machines came to the front in together with bringing out production line to supply growing demand, and so the importance the art had diminished. The machines having some features like standard production, scales based on rules and geometric form having unnatural appearance caused the artists such as William Morris and John Ruskin to believe that the machine harmed the art. The artists such as Morris and Ruskin took a leading role in development of design idea by resisting the form of machine production devoid of art in the light of this ideas. The problem of design keeps as a current issue nowadays. That’s why, we could create a solution by having different perspectives based on previous experience and problems encountered nowadays. The problem of design keeps on up-to-date issue with the technology developing very fast today. So, this study was made with the aim to help us present right approaches towards today’s problems. This research, review of the literature obtained from architecture, history of art and industrial design on books- magazines the subject of the dissertation thesis Higher Education Center was formed with descriptive narratives. Another aim of the research carried out in this context the handmade, machine design is to examine the emerging issues in the transition to production.

  2. Läbi legendide William Shakespeare'i poole / Maris Peters

    Index Scriptorium Estoniae

    Peters, Maris

    2010-01-01

    Tutvustus: Wells, Stanley. Kas on tõsi, et Shakespeare ...? / tõlkinud Maris Peters. Tallinn : Argo, 2010. Raamat William Shakespeare kohta käivatest legendidest, kuuldustest ja teooriatest ning tema teoste autorsusest

  3. Case report of sudden death in a child with Williams syndrome ...

    African Journals Online (AJOL)

    A two year old child, confirmed with Williams syndrome (WS) ... and no relevant cardiac history such as chest pain or episodes ... brain, abdominal and pelvic organ blocks. .... a fully functional operating theatre complex presents a number.

  4. Prince William Sound, Alaska ESI: ESI (Environmental Sensitivity Index Shoreline Types)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  5. Prince William Sound, Alaska ESI: M_MAMMAL (Marine Mammal Polygons)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

  6. Lähtugem ehitistest! / William J. R. Curtis ; interv. Andres Kurg, Karin Hallas, Triin Ojari

    Index Scriptorium Estoniae

    Curtis, William J. R.

    1998-01-01

    24. apr. pidas Rotermanni soolalaos loengu arhitektuuriajaloolane William J. R. Curtis. Katkeid jutuajamisest W. Curtisega. Arhitektuurikriitikast, oma raamatust "Modern Architecture since 1900", millest W. Curtis praegu kriitikuna kirjutab, Lille'i projektist jm

  7. John Whitridge Williams, MD (1866–1931) of Baltimore: pioneer of academic obstetrics

    Science.gov (United States)

    Dunn, P M

    2007-01-01

    Williams was the founder of academic obstetrics in the United States and with his textbook was the recognised leader of this discipline in America during the first 30 years of the 20th century. PMID:17185435

  8. Regionaalpoliitika ja arhitektuur / Ülar Mark

    Index Scriptorium Estoniae

    Mark, Ülar

    1999-01-01

    Kagu-Eesti Regionaalarengu Programmi raames Eesti Kunstiakadeemia arhitektuurikateedri IV kursuse eriala valikaines 1998/99 tehtud tööst "HyperMobiilne Reaalsus & Kagu Eesti" (juhendajad Ralf Tamm, Ülar Mark). Ühises töös osalesid Tartu Ülikooli geograafiatudengid (juhendaja Rein Ahas). 4 illustratsiooni

  9. Nekroloog turundusele / Mark Earls ; interv. Margo Kokerov

    Index Scriptorium Estoniae

    Earls, Mark

    2003-01-01

    Turunduskommunikatsioonifirma Ogilvy & Mather suunajuht Mark Earls leiab, et kuna turg on üle ujutatud võrdselt heade toodetega ja tarbija teab, et tegelikult pole oluline, millise toote ta valib, muutub turundusrevolutsiooni keskne idee - tarbijavajaduste kindlakstegemine ja rahuldamine - tähtsusetuks.

  10. 49 CFR 15.13 - Marking SSI.

    Science.gov (United States)

    2010-10-01

    ... SSI. (a) Marking of paper records. In the case of paper records containing SSI, a covered person must... limitation statement on the bottom, of— (1) The outside of any front and back cover, including a binder cover... types of records. In the case of non-paper records that contain SSI, including motion picture films...

  11. Monopoly, Pareto and Ramsey mark-ups

    NARCIS (Netherlands)

    Ten Raa, T.

    2009-01-01

    Monopoly prices are too high. It is a price level problem, in the sense that the relative mark-ups have Ramsey optimal proportions, at least for independent constant elasticity demands. I show that this feature of monopoly prices breaks down the moment one demand is replaced by the textbook linear

  12. Globaalne palavik ja Nord Stream / Mark Soosaar

    Index Scriptorium Estoniae

    Soosaar, Mark, 1946-

    2009-01-01

    Riigikogu keskkonnakomisjoni liikme Mark Soosaare sõnul peaks Eesti Taani eeskujul jõudma parlamentaarse otsuseni loobuda tuumajaamaehitusest, vähendada tuleks märgatavalt Eesti metsade raiumist. Vene-Saksa gaasitarneleppe vastu töötamise asemel tuleks otsida ühisosa nii Venemaa kui teiste Läänemeremaadega

  13. Teaching Mark through a postcolonial optic

    African Journals Online (AJOL)

    2015-07-16

    Jul 16, 2015 ... question, eliciting answers that range from Mark as in direct and open ... or armed response, especially in a context where such actions were unrealistic. (whether ..... identity; social memory; to name a few) of power. It implies ... an elite-driven enterprise in the simplistic sense of the word, although the elite's ...

  14. First results from Mark II at SPEAR

    International Nuclear Information System (INIS)

    Abrams, G.S.; Alam, M.S.; Blocker, C.A.

    1979-05-01

    First results from the SLAC-LBL Mark II magnetic detector at SPEAR are presented. The performance of the detector is discussed and preliminary results are given on inclusive baryon production R/sub p + anti p/, R/sub Λ + anti Λ/, on decay modes of the D mesons and on two-photon production of eta' mesons

  15. 15 CFR 1150.3 - Approved markings.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Approved markings. 1150.3 Section 1150.3 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued... permanently affixed to the exterior surface of the barrel, covering the circumference of the barrel from the...

  16. 22 CFR 226.91 - Marking.

    Science.gov (United States)

    2010-04-01

    ... Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Miscellaneous § 226.91 Marking. (a) USAID policy is that all programs, projects, activities... support of the American people through the United States Agency for International Development (USAID). The...

  17. Fingerprint Analysis with Marked Point Processes

    DEFF Research Database (Denmark)

    Forbes, Peter G. M.; Lauritzen, Steffen; Møller, Jesper

    We present a framework for fingerprint matching based on marked point process models. An efficient Monte Carlo algorithm is developed to calculate the marginal likelihood ratio for the hypothesis that two observed prints originate from the same finger against the hypothesis that they originate from...... different fingers. Our model achieves good performance on an NIST-FBI fingerprint database of 258 matched fingerprint pairs....

  18. A Collar for Marking Big Game Animals

    Science.gov (United States)

    Robert L. Phillips

    1970-01-01

    A Simple, inexpensive collar made of Armor-tite (a vinyl-coated nylon fabric) was designed for marking white-tailed deer (Odocoileus virginianus) and moose (Alces alces). Field tests showed that the material is easily seen and extrememly durable. It may be suitable for use on other large mammals. The collar can be quickly fitted to individual animals under field...

  19. The Four Marks of Holistic Kinesiology

    Science.gov (United States)

    Twietmeyer, Gregg

    2012-01-01

    What, to borrow a theological phrase, are the marks of a truly holistic kinesiology department? "In Kinesis and the Nature of the Human Person" (2010), I examined the theoretical impact of Aristotle's definition of "kinesis" and Polanyi's theory of "tacit knowledge" on kinesiology. The intention here, however, is practical rather than theoretical.…

  20. Marks & Spencer loob ELis maksupretsedenti / Sirje Rank

    Index Scriptorium Estoniae

    Rank, Sirje, 1966-

    2005-01-01

    Ilmunud ka: Delovõje Vedomosti 13. apr. lk. 6. Briti rõivakett Marks & Spencer kaebas, et Briti maksuseadused, mis ei lubanud emafirma Suurbritannias maksustavast tulust maha kanda Saksamaal, Prantsusmaal ja Belgias asunud tütarfirmade suuri kahjumeid üheksakümnendate aastate lõpus, on vastuolus EL-i ühisturu seadustega

  1. Do clinicians use more question marks?

    NARCIS (Netherlands)

    Zijlmans, Maeike; Otte, Willem M; Van't Klooster, Maryse A; van Diessen, Eric; Leijten, Frans Ss; Sander, Josemir W

    2015-01-01

    OBJECTIVE: To quantify the use of question marks in titles of published studies. DESIGN AND SETTING: Literature review. PARTICIPANTS: All Pubmed publications between 1 January 2013 and 31 December 2013 with an available abstract. Papers were classified as being clinical when the search terms clin*,

  2. 27 CFR 28.216 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.216 Section 28.216 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS EXPORTATION OF ALCOHOL Exportation of Wine With Benefit of Drawback § 28.216...

  3. Primary Science Quality Mark--2016 Update

    Science.gov (United States)

    Turner, Jane

    2016-01-01

    Back in May 2011, an article in "Primary Science" described how the idea for a quality mark for primary science was developed from an initial conversation at an Association for Science Education annual conference (Turner, Marshall and Elsmore, 2011). Its intention then, as now, was to support and champion good practice and raise the…

  4. Application of Choi—Williams Reduced Interference Time Frequency Distribution to Machinery Diagnostics

    Directory of Open Access Journals (Sweden)

    Howard A. Gaberson

    1995-01-01

    Full Text Available This article discusses time frequency analysis of machinery diagnostic vibration signals. The short time Fourier transform, the Wigner, and the Choi–Williams distributions are explained and illustrated with test cases. Examples of Choi—Williams analyses of machinery vibration signals are presented. The analyses detect discontinuities in the signals and their timing, amplitude and frequency modulation, and the presence of different components in a vibration signal.

  5. Binding of Visual and Spatial Short-Term Memory in Williams Syndrome and Moderate Learning Disability

    Science.gov (United States)

    Jarrold, Christopher; Phillips, Caroline; Baddeley, Alan D

    2007-01-01

    A main aim of this study was to test the claim that individuals with Williams syndrome have selectively impaired memory for spatial as opposed to visual information. The performance of 16 individuals with Williams syndrome (six males, 10 females; mean age 18y 7mo [SD 7y 6mo], range 9y 1mo-30y 7mo) on tests of short-term memory for item and…

  6. White matter integrity deficits in prefrontal-amygdala pathways in Williams syndrome.

    Science.gov (United States)

    Avery, Suzanne N; Thornton-Wells, Tricia A; Anderson, Adam W; Blackford, Jennifer Urbano

    2012-01-16

    Williams syndrome is a neurodevelopmental disorder associated with significant non-social fears. Consistent with this elevated non-social fear, individuals with Williams syndrome have an abnormally elevated amygdala response when viewing threatening non-social stimuli. In typically-developing individuals, amygdala activity is inhibited through dense, reciprocal white matter connections with the prefrontal cortex. Neuroimaging studies suggest a functional uncoupling of normal prefrontal-amygdala inhibition in individuals with Williams syndrome, which might underlie both the extreme amygdala activity and non-social fears. This functional uncoupling might be caused by structural deficits in underlying white matter pathways; however, prefrontal-amygdala white matter deficits have yet to be explored in Williams syndrome. We used diffusion tensor imaging to investigate prefrontal-amygdala white matter integrity differences in individuals with Williams syndrome and typically-developing controls with high levels of non-social fear. White matter pathways between the amygdala and several prefrontal regions were isolated using probabilistic tractography. Within each pathway, we tested for between-group differences in three measures of white matter integrity: fractional anisotropy (FA), radial diffusivity (RD), and parallel diffusivity (λ(1)). Individuals with Williams syndrome had lower FA, compared to controls, in several of the prefrontal-amygdala pathways investigated, indicating a reduction in white matter integrity. Lower FA in Williams syndrome was explained by significantly higher RD, with no differences in λ(1), suggestive of lower fiber density or axon myelination in prefrontal-amygdala pathways. These results suggest that deficits in the structural integrity of prefrontal-amygdala white matter pathways might underlie the increased amygdala activity and extreme non-social fears observed in Williams syndrome. Copyright © 2011 Elsevier Inc. All rights reserved.

  7. Distinguishing butchery cut marks from crocodile bite marks through machine learning methods.

    Science.gov (United States)

    Domínguez-Rodrigo, Manuel; Baquedano, Enrique

    2018-04-10

    All models of evolution of human behaviour depend on the correct identification and interpretation of bone surface modifications (BSM) on archaeofaunal assemblages. Crucial evolutionary features, such as the origin of stone tool use, meat-eating, food-sharing, cooperation and sociality can only be addressed through confident identification and interpretation of BSM, and more specifically, cut marks. Recently, it has been argued that linear marks with the same properties as cut marks can be created by crocodiles, thereby questioning whether secure cut mark identifications can be made in the Early Pleistocene fossil record. Powerful classification methods based on multivariate statistics and machine learning (ML) algorithms have previously successfully discriminated cut marks from most other potentially confounding BSM. However, crocodile-made marks were marginal to or played no role in these comparative analyses. Here, for the first time, we apply state-of-the-art ML methods on crocodile linear BSM and experimental butchery cut marks, showing that the combination of multivariate taphonomy and ML methods provides accurate identification of BSM, including cut and crocodile bite marks. This enables empirically-supported hominin behavioural modelling, provided that these methods are applied to fossil assemblages.

  8. 19 CFR 11.9 - Special marking on certain articles.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Special marking on certain articles. 11.9 Section... OF THE TREASURY PACKING AND STAMPING; MARKING Marking § 11.9 Special marking on certain articles. (a... of additional U.S. Note 4, Chapter 91. If any article so required to be marked is found not to be...

  9. 19 CFR 134.43 - Methods of marking specific articles.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Methods of marking specific articles. 134.43...; DEPARTMENT OF THE TREASURY COUNTRY OF ORIGIN MARKING Method and Location of Marking Imported Articles § 134.43 Methods of marking specific articles. (a) Marking previously required by certain provisions of the...

  10. The total column of CO2 and CH4 measured with a compact Fourier transform spectrometer at NASA Armstrong Flight Research Center and Railroad Valley, Nevada, USA

    Science.gov (United States)

    Kawakami, S.; Shiomi, K.; Suto, H.; Kuze, A.; Hillyard, P. W.; Tanaka, T.; Podolske, J. R.; Iraci, L. T.; Albertson, R. T.

    2014-12-01

    The total columns of carbon dioxide (XCO2) and methane (XCH4) were measured with a compact Fourier transform spectrometer (FTS) at NASA Armstrong Flight Research Center (AFRC) and Railroad Valley, Nevada, USA (RRV) during a vicarious calibration campaign in June 2014. The campaign was performed to estimate changes in the radiometric response of the Thermal and Near Infrared Sensor for carbon Observations Fourier Transform Spectrometer (TANSO-FTS) and the Cloud and Aerosol Imager (TANSO-CAI) aboard Greenhouse gases Observing SATellite (GOSAT). TANSO-FTS measures spectra of radiance scattered by the Earth surface with high- and medium-gain depending on the surface reflectance. At high reflectance areas, such as deserts over north Africa and Australia, TANSO-FTS collects spectra with medium-gain. There was differences on atmospheric pressure and XCO2 retrieved from spectra obtained between high-gain and medium-gain. Because the retrieved products are useful for evaluating the difference of spectral qualities between high- and medium-gain, this work is an attempt to collect validation data for spectra with medium-gain of TANSO-FTS at remote and desert area with a compact and medium-spectral resolution instrument. As a compact FTS, EM27/SUN was used. It was manufactured and newly released on April 1, 2014 by Bruker. It is robust and operable in a high temperature environment. It was housed in a steel box to protect from dust and rain and powered by Solar panels. It can be operated by such a remote and desert area, like a RRV. Over AFRC and RRV, vertical profiles of CO2 and CH4 were measured using the Alpha Jet research aircraft as part of the Alpha Jet Atmospheric eXperiment (AJAX) of ARC, NASA. The values were calibrated to standard gases. To make the results comparable to WMO (World Meteorological Organization) standards, the retrieved XCO2 and XCH4 values are divided by a calibration factor. This values were determined by comparisons with in situ profiles measured by

  11. Using novel control groups to dissect the amygdala's role in Williams syndrome.

    Science.gov (United States)

    Thornton-Wells, Tricia A; Avery, Suzanne N; Blackford, Jennifer Urbano

    2011-07-01

    Williams syndrome is a neurodevelopmental disorder with an intriguing behavioral phenotype-hypersociability combined with significant non-social fears. Previous studies have demonstrated abnormalities in amygdala function in individuals with Williams syndrome compared to typically-developing controls. However, it remains unclear whether the findings are related to the atypical neurodevelopment of Williams syndrome, or are also associated with behavioral traits at the extreme end of a normal continuum. We used functional magnetic resonance imaging (fMRI) to compare amygdala blood-oxygenation-level-dependent (BOLD) responses to non-social and social images in individuals with Williams syndrome compared to either individuals with inhibited temperament (high non-social fear) or individuals with uninhibited temperament (high sociability). Individuals with Williams syndrome had larger amygdala BOLD responses when viewing the non-social fear images than the inhibited temperament control group. In contrast, when viewing both fear and neutral social images, individuals with Williams syndrome did not show smaller amygdala BOLD responses relative to the uninhibited temperament control group, but instead had amygdala responses proportionate to their sociability. These results suggest heightened amygdala response to non-social fear images is characteristic of WS, whereas, variability in amygdala response to social fear images is proportionate to, and might be explained by, levels of trait sociability.

  12. Autistic disorder in patients with Williams-Beuren syndrome: a reconsideration of the Williams-Beuren syndrome phenotype.

    Science.gov (United States)

    Tordjman, Sylvie; Anderson, George M; Botbol, Michel; Toutain, Annick; Sarda, Pierre; Carlier, Michèle; Saugier-Veber, Pascale; Baumann, Clarisse; Cohen, David; Lagneaux, Céline; Tabet, Anne-Claude; Verloes, Alain

    2012-01-01

    Williams-Beuren syndrome (WBS), a rare developmental disorder caused by deletion of contiguous genes at 7q11.23, has been characterized by strengths in socialization (overfriendliness) and communication (excessive talkativeness). WBS has been often considered as the polar opposite behavioral phenotype to autism. Our objective was to better understand the range of phenotypic expression in WBS and the relationship between WBS and autistic disorder. The study was conducted on 9 French individuals aged from 4 to 37 years old with autistic disorder associated with WBS. Behavioral assessments were performed using Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS) scales. Molecular characterization of the WBS critical region was performed by FISH. FISH analysis indicated that all 9 patients displayed the common WBS deletion. All 9 patients met ADI-R and ADOS diagnostic criteria for autism, displaying stereotypies and severe impairments in social interaction and communication (including the absence of expressive language). Additionally, patients showed improvement in social communication over time. The results indicate that comorbid autism and WBS is more frequent than expected and suggest that the common WBS deletion can result in a continuum of social communication impairment, ranging from excessive talkativeness and overfriendliness to absence of verbal language and poor social relationships. Appreciation of the possible co-occurrence of WBS and autism challenges the common view that WBS represents the opposite behavioral phenotype of autism, and might lead to improved recognition of WBS in individuals diagnosed with autism.

  13. The rhetorical strategy of William Paley's Natural theology (1802): part 1, William Paley's Natural theology in context.

    Science.gov (United States)

    O'Flaherty, Niall

    2010-03-01

    This article reconstructs the historical and philosophical contexts of William Paley's Natural theology (1802). In the wake of the French Revolution, widely believed to be the embodiment of an atheistic political credo, the refutation of the transmutational biological theories of Buffon and Erasmus Darwin was naturally high on Paley's agenda. But he was also responding to challenges arising from his own moral philosophy, principally the psychological quandary of how men were to be kept in mind of the Creator. It is argued here that Natural theology was the culmination of a complex rhetorical scheme for instilling religious impressions that would increase both the virtue and happiness of mankind. Philosophy formed an integral part of this strategy, but it did not comprise the whole of it. Equally vital were those purely rhetorical aspects of the discourse which, according to Paley, were more concerned with creating 'impression'. This facet of his writing is explored in part one of this two-part article. Turning to the argumentative side of the scheme, part two examines Paley's responses to David Hume and Erasmus Darwin in the light of the wider strategy of inculcation at work throughout all his writings.

  14. Rock Uplift above the Yakutat Megathrust on Montague Island, Prince William Sound, Alaska

    Science.gov (United States)

    Ferguson, K.; Armstrong, P. A.; Haeussler, P. J.; Arkle, J. C.

    2011-12-01

    The Yakutat microplate is subducting shallowly (~6°) beneath the North American Plate at a rate of approximately 53 mm/yr to the northwest. Deformation from this flat- slab subduction extends >600 km inland and has resulted in regions of focused rock uplift and exhumation in the Alaska Range, central Chugach Mountains, and St. Elias Mountains. Many questions still remain about how strain is partitioned between these regions of focused uplift, particularly in the Prince William Sound (southern Chugach Mountains) on Montague Island. Montague Island (and adjacent Hinchinbrook Island) are ~20 km above the megathrust where there is a large degree of coupling between the subducting Yakutat microplate and overriding North American Plate. Montague Island is of particular interest because it lies between two areas of rapid rock uplift focused in the St. Elias/eastern Chugach Mountains and the western Chugach Mountains. In the St. Elias/eastern Chugach Mountains, faulting related to collisional processes and bending of fault systems causes rapid rock uplift. About 200 km farther northwest in the western Chugach Mountains, recent rock uplift is caused by underplating along the megathrust that is focused within a syntaxial bend of major fault systems and mountain ranges. Montague Island bounds the southern margin of Prince William Sound, and is steep, narrow, and elongate (81 km long and ~15 km wide). The maximum relief is 914 m, making for very steep, mountainous topography considering the narrow width of the island. During the Mw 9.2 earthquake in 1964, the Patton Bay and Hanning Bay reverse faults were reactivated, with 7 and 5 m of vertical offset, respectively. Both faults dip ~60° NW and strike NE-SW parallel to the long-axis of the island and parallel to geomorphic features including lineaments, elongate valleys, and escarpments. Prominent ~450 m high escarpments are present along the SE-facing side of the island, which suggests rapid and sustained uplift. New apatite

  15. Minnesota Local Agency Pavement Marking : Mining Existing Data

    Science.gov (United States)

    2017-11-01

    Pavement marking is important for safety. Maximizing pavement marking performance in terms of increased retroreflectivity, within limited budget constraints, allows agencies to make better decisions toward providing more effective pavement marking pe...

  16. William Bradley Coley, MD, and the phenomenon of spontaneous regression

    Directory of Open Access Journals (Sweden)

    Vernon LF

    2018-04-01

    Full Text Available Leonard F Vernon Sherman College of Chiropractic, Spartanburg, SC, USA Abstract: The standard definition of spontaneous regression (SR of cancer is as follows, “…when a malignant tumor partially or completely disappears without treatment or in the presence of therapy which is considered inadequate to exert a significant influence on neoplastic disease.” SR is also known as Saint Peregrine tumor, the name taken from a young priest, Peregrine Laziosi (1260 [5]–1345, exact date is unknown, who had been diagnosed with a tumor of the tibia. The mass eventually grew so large that it broke through the skin and became severely infected. The available treatment for this condition was limited to amputation. Historical records report that on the day of surgery, physicians found that the tumor had disappeared and reportedly never returned. To date, the medical literature consists only of individual case studies and overviews of this phenomenon. The most cited work on the subject was done by surgeons Tilden Everson and Warren Cole who reviewed 176 published cases of SR from 1900 to 1960. While a percentage of these were found not to be cases of SR, there remained a number of unexplained cases. A frequent theme in many cases of SR is the co-occurrence of infection. Given the current interest in immunotherapy in the treatment of cancer, this article discusses one of the very early pioneers of this theory, William Bradley Coley, MD, a surgeon who was clearly ahead of his time. Ostracized by colleagues for his belief that stimulation of the immune system could in fact produce a regression of cancer, Coley remained convinced that his theory was right and, while he was not familiar with cytokines such as tumor necrosis factor (TNF, interferons, and streptokinase, he knew instinctively that an innate immune response was taking place. Keywords: autoimmunity, cancer, fever, infection, immunotherapy, tumor, cytokines

  17. Strain accumulation across the Prince William Sound asperity, Southcentral Alaska

    Science.gov (United States)

    Savage, J. C.; Svarc, J. L.; Lisowski, M.

    2015-03-01

    The surface velocities predicted by the conventional subduction model are compared to velocities measured in a GPS array (surveyed in 1993, 1995, 1997, 2000, and 2004) spanning the Prince William Sound asperity. The observed velocities in the comparison have been corrected to remove the contributions from postseismic (1964 Alaska earthquake) mantle relaxation. Except at the most seaward monument (located on Middleton Island at the seaward edge of the continental shelf, just 50 km landward of the deformation front in the Aleutian Trench), the corrected velocities qualitatively agree with those predicted by an improved, two-dimensional, back slip, subduction model in which the locked megathrust coincides with the plate interface identified by seismic refraction surveys, and the back slip rate is equal to the plate convergence rate. A better fit to the corrected velocities is furnished by either a back slip rate 20% greater than the plate convergence rate or a 30% shallower megathrust. The shallow megathrust in the latter fit may be an artifact of the uniform half-space Earth model used in the inversion. Backslip at the plate convergence rate on the megathrust mapped by refraction surveys would fit the data as well if the rigidity of the underthrust plate was twice that of the overlying plate, a rigidity contrast higher than expected. The anomalous motion at Middleton Island is attributed to continuous slip at near the plate convergence rate on a postulated, listric fault that splays off the megathrust at depth of about 12 km and outcrops on the continental slope south-southeast of Middleton Island.

  18. Strain accumulation across the Prince William Sound asperity, Southcentral Alaska

    Science.gov (United States)

    Savage, James C.; Svarc, Jerry L.; Lisowski, Michael

    2015-01-01

    The surface velocities predicted by the conventional subduction model are compared to velocities measured in a GPS array (surveyed in 1993, 1995, 1997, 2000, and 2004) spanning the Prince William Sound asperity. The observed velocities in the comparison have been corrected to remove the contributions from postseismic (1964 Alaska earthquake) mantle relaxation. Except at the most seaward monument (located on Middleton Island at the seaward edge of the continental shelf, just 50 km landward of the deformation front in the Aleutian Trench), the corrected velocities qualitatively agree with those predicted by an improved, two-dimensional, back slip, subduction model in which the locked megathrust coincides with the plate interface identified by seismic refraction surveys, and the back slip rate is equal to the plate convergence rate. A better fit to the corrected velocities is furnished by either a back slip rate 20% greater than the plate convergence rate or a 30% shallower megathrust. The shallow megathrust in the latter fit may be an artifact of the uniform half-space Earth model used in the inversion. Backslip at the plate convergence rate on the megathrust mapped by refraction surveys would fit the data as well if the rigidity of the underthrust plate was twice that of the overlying plate, a rigidity contrast higher than expected. The anomalous motion at Middleton Island is attributed to continuous slip at near the plate convergence rate on a postulated, listric fault that splays off the megathrust at depth of about 12 km and outcrops on the continental slope south-southeast of Middleton Island.

  19. Incontinence in children, adolescents and adults with Williams syndrome.

    Science.gov (United States)

    von Gontard, Alexander; Niemczyk, Justine; Borggrefe-Moussavian, Sorina; Wagner, Catharina; Curfs, Leopold; Equit, Monika

    2016-11-01

    Williams Syndrome (WS) is a microdeletion syndrome (chromosome 7q11.23) characterized by typical facial features, cardiovascular disease, behavioural symptoms, and mild intellectual disability (ID). The aim of this study was to assess the rates of incontinence and psychological problems in persons with WS. 231 individuals with WS were recruited through the German parent support group (52.0% male, mean age 19.4 years). Faecal incontinence (FI) was diagnosed from the age of 4 years and nocturnal enuresis (NE) and daytime urinary incontinence (DUI) of 5 years onwards. The Parental Questionnaire: Enuresis/Urinary Incontinence, the International-Consultation-on-Incontinence-Questionnaire-Pediatric LUTS (ICIQ-CLUTS), as well as the Developmental Behavior Checklist for parents (DBC-P) or for adults (DBC-A) were filled out by parents or caregivers. 17.8% of the sample had NE, 5.9% DUI and 7.6% FI. NE was present in 44.9% of children (4-12 years), 13.5% of teens (13-17y), 3.3% of young adults (18-30y) and in 3.6% of adults (> 30y). DUI (and FI) decreased from 17.9% (21.4%) in children to 0% in adults. 3.5% of the sample had an ICIQ-CLUTS score in the clinical range. 30.5% of children and 22.1% of adults had a clinical DBC score. Children and teens with clinically relevant DBC-P-scores had significantly higher DUI rates. Children with WS have high rates of incontinence and LUTS, which decrease with age. Most adults are continent. NE is the most common subtype. Except for DUI in children, incontinence is not associated with behavioural problems. Screening, assessment and treatment of incontinence in individuals with WS is recommended. Neurourol. Urodynam. 35:1000-1005, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  20. Pragmatic Abilities of Children with Williams Syndrome: A Longitudinal Examination

    Directory of Open Access Journals (Sweden)

    Angela E. John

    2012-06-01

    Full Text Available Although prior research has indicated that pragmatics is an area of particular weakness for individuals with Williams syndrome (WS, the relations among different pragmatic abilities and the relations between pragmatic ability and expressive vocabulary ability have yet to be addressed. In addition, analyses of the relations between the same type of pragmatic ability over time have not been reported. The present study was designed to address these questions. We considered the pragmatic language abilities of 14 children with WS at two time points: as 4-year-olds during a 30-minute play-session with their mothers (Time 1 and an average of 5.87 years later during a one-on-one conversation with a familiar researcher (Time 2. Children’s intellectual and expressive vocabulary abilities were assessed at both time points. Results indicated that the ability to verbally contribute information beyond what was required in response to a question was significantly related to the ability to verbally contribute new information in the absence of a question both at age 4 years and during primary school. At age 4, both the ability to pair verbalizations with eye contact (intersubjectivity and expressive vocabulary ability were related to the ability to verbally contribute information beyond what was expected within a social interaction. Finally, the ability to verbally contribute new information to a social interaction beyond what was required to answer a question and the ability to pair verbalizations with eye contact (intersubjectivity at age 4 years predicted the ability to verbally contribute new information beyond what was required to answer a question at age 9 – 12 years. The theoretical implications of our findings and the importance of early pragmatic language intervention for children who have WS are discussed.

  1. Pragmatic Abilities of Children with Williams Syndrome: A Longitudinal Examination

    Science.gov (United States)

    John, Angela E.; Dobson, Lauren A.; Thomas, Lauren E.; Mervis, Carolyn B.

    2012-01-01

    Prior research has indicated that pragmatics is an area of particular weakness for individuals with Williams syndrome (WS). To further address this aspect of the WS social phenotype, we used an individual differences approach to consider both cross-sectional and longitudinal relations among different pragmatic abilities for 14 children with WS, taking into account individual differences in non-verbal reasoning abilities. We also considered the relations between pragmatic abilities and expressive vocabulary ability. Participants were tested at two time points: as 4-year-olds during a 30-min play session with their mothers (Time 1) and an average of 5.87 years later during a one-on-one conversation with a familiar researcher (Time 2). Children’s intellectual and expressive vocabulary abilities were assessed at both time points. Results indicated that the ability to verbally contribute information beyond what was required in response to a question (ExtendQ) was significantly related to the ability to verbally contribute new information in the absence of a question (ExtendS) both at age 4 years and during primary school. At age 4, both the ability to pair verbalizations with eye contact in triadic interactions (secondary intersubjectivity) and expressive vocabulary ability were related to both ExtendQ and ExtendS. Finally, both ExtendQ and the ability to pair verbalizations with eye contact (intersubjectivity) at age 4 years predicted ExtendQ at age 9–12 years. The theoretical implications of our findings and the importance of early pragmatic language intervention for children who have WS are discussed. PMID:22719734

  2. Dissociation of spatial memory systems in Williams syndrome.

    Science.gov (United States)

    Bostelmann, Mathilde; Fragnière, Emilie; Costanzo, Floriana; Di Vara, Silvia; Menghini, Deny; Vicari, Stefano; Lavenex, Pierre; Lavenex, Pamela Banta

    2017-11-01

    Williams syndrome (WS), a genetic deletion syndrome, is characterized by severe visuospatial deficits affecting performance on both tabletop spatial tasks and on tasks which assess orientation and navigation. Nevertheless, previous studies of WS spatial capacities have ignored the fact that two different spatial memory systems are believed to contribute parallel spatial representations supporting navigation. The place learning system depends on the hippocampal formation and creates flexible relational representations of the environment, also known as cognitive maps. The spatial response learning system depends on the striatum and creates fixed stimulus-response representations, also known as habits. Indeed, no study assessing WS spatial competence has used tasks which selectively target these two spatial memory systems. Here, we report that individuals with WS exhibit a dissociation in their spatial abilities subserved by these two memory systems. As compared to typically developing (TD) children in the same mental age range, place learning performance was impaired in individuals with WS. In contrast, their spatial response learning performance was facilitated. Our findings in individuals with WS and TD children suggest that place learning and response learning interact competitively to control the behavioral strategies normally used to support human spatial navigation. Our findings further suggest that the neural pathways supporting place learning may be affected by the genetic deletion that characterizes WS, whereas those supporting response learning may be relatively preserved. The dissociation observed between these two spatial memory systems provides a coherent theoretical framework to characterize the spatial abilities of individuals with WS, and may lead to the development of new learning strategies based on their facilitated response learning abilities. © 2017 Wiley Periodicals, Inc.

  3. A Comparative Investigation on the Capability of Modified Zerilli-Armstrong and Arrhenius-Type Constitutive Models to Describe Flow Behavior of BFe10-1-2 Cupronickel Alloy at Elevated Temperature

    Science.gov (United States)

    Cai, Jun; Lei, Ying; Wang, Kuaishe; Zhang, Xiaolu; Miao, Chengpeng; Li, Wenbing

    2016-05-01

    True stress and true strain data obtained from isothermal compression tests on a Gleeble-3800 thermo-mechanical simulator, in a wide range of temperatures (1073-1323 K) and strain rates (0.001-10 s-1), has been used to evaluate the material constants of two constitutive models: the modified Zerilli-Armstrong and the strain compensation Arrhenius-type models. Furthermore, a comparative study was conducted on the capabilities of the two models in order to represent the elevated temperature flow behavior of BFe10-1-2 cupronickel alloy. The suitability levels of these two models were evaluated by comparing the accuracy of their predictions of deformation behavior, correlation coefficient ( R), average absolute relative error ( AARE), relative errors of prediction, and the number of material constants. The results show that the predicted values of these two models agree well with the experimental values of BFe10-1-2 cupronickel alloy except at the temperature of 1123 K and the strain rate of 1 s-1. Meanwhile, the strain compensated Arrhenius-type model can track the deformation behavior of BFe10-1-2 cupronickel alloy more accurately throughout the entire temperature and strain rate range, while fewer material constants are involved in the modified Zerilli-Armstrong model.

  4. WEAVE: the next generation wide-field spectroscopy facility for the William Herschel Telescope : The next generation wide-field spectroscopy facility for the William Herschel Telescope

    NARCIS (Netherlands)

    Dalton, Gavin; Trager, Scott C.; Abrams, Don Carlos; Carter, David; Bonifacio, Piercarlo; Aguerri, J. Alfonso L.; MacIntosh, Mike; Evans, Chris; Lewis, Ian; Navarro, Ramon; Agocs, Tibor; Dee, Kevin; Rousset, Sophie; Tosh, Ian; Middleton, Kevin; Pragt, Johannes; Terrett, David; Brock, Matthew; Benn, Chris; Verheijen, Marc; Cano Infantes, Diego; Bevil, Craige; Steele, Iain; Mottram, Chris; Bates, Stuart; Gribbin, Francis J.; Rey, Jürg; Rodriguez, Luis Fernando; Delgado, Jose Miguel; Guinouard, Isabelle; Walton, Nic; Irwin, Michael J.; Jagourel, Pascal; Stuik, Remko; Gerlofsma, Gerrit; Roelfsma, Ronald; Skillen, Ian; Ridings, Andy; Balcells, Marc; Daban, Jean-Baptiste; Gouvret, Carole; Venema, Lars; Girard, Paul

    We present the preliminary design of the WEAVE next generation spectroscopy facility for the William Herschel Telescope (WHT), principally targeting optical ground-based follow up of upcoming ground-based (LOFAR) and spacebased (Gaia) surveys. WEAVE is a multi-object and multi-IFU facility utilizing

  5. Revised Mark 22 coolant temperature coefficients

    International Nuclear Information System (INIS)

    Graves, W.E.

    1987-01-01

    Coolant temperature coefficients for the Mark 22 charge published previously are non-conservative because of the neglect of a significant mechanism which has a positive contribution to reactivity. Even after correcting for this effect, dynamic tests made on a Mark VIB charge in the early 60's suggest the results are still non-conservative. This memorandum takes both of these sources of information into account in making a best estimate of the prompt (coolant plus metal) temperature coefficient. Although no safety issues arise from this work (the overall temperature coefficient still strongly contributes to reactor stability), it is obviously desirable to use best estimates for prompt coefficients in limits and other calculations

  6. EcoMark 2.0

    DEFF Research Database (Denmark)

    Guo, Chenjuan; Yang, Bin; Andersen, Ove

    2015-01-01

    Eco-routing is a simple yet effective approach to substantially reducing the environmental impact, e.g., fuel consumption and greenhouse gas (GHG) emissions, of vehicular transportation. Eco-routing relies on the ability to reliably quantify the environmental impact of vehicles as they travel...... in a spatial network. The procedure of quantifying such vehicular impact for road segments of a spatial network is called eco-weight assignment. EcoMark 2.0 proposes a general framework for eco-weight assignment to enable eco-routing. It studies the abilities of six instantaneous and five aggregated models......, and experiments for assessing the utility of the impact models in assigning eco-weights. The application of EcoMark 2.0 indicates that the instantaneous model EMIT and the aggregated model SIDRA-Running are suitable for assigning eco-weights under varying circumstances. In contrast, other instantaneous models...

  7. Geologic bench marks by terrestrial photography

    Science.gov (United States)

    Malde, Harold E.

    1973-01-01

    A photograph made with a level camera, if taken at a known height above a permanent mark on the ground, can be later repeated with exactness for measurement of changes in terrain. Such a photograph is one of several means for establishing a geologic bench mark and is especially useful for monitoring the subtle qualities of a landscape that are otherwise hard to map and describe, including the effects of man's use. Moreover, the geometry of such a photograph provides the same angular measurements between objects as can be made with a transit. A measurement of distance on a single photograph, however, requires control points. These can be surveyed at any convenient time, not necessarily when the initial photograph is made. Distances can also be determined by simple stereophotography from a base line of suitable length.

  8. Identification marking by means of laser peening

    Science.gov (United States)

    Hackel, Lloyd A.; Dane, C. Brent; Harris, Fritz

    2002-01-01

    The invention is a method and apparatus for marking components by inducing a shock wave on the surface that results in an indented (strained) layer and a residual compressive stress in the surface layer. One embodiment of the laser peenmarking system rapidly imprints, with single laser pulses, a complete identification code or three-dimensional pattern and leaves the surface in a state of deep residual compressive stress. A state of compressive stress in parts made of metal or other materials is highly desirable to make them resistant to fatigue failure and stress corrosion cracking. This process employs a laser peening system and beam spatial modulation hardware or imaging technology that can be setup to impress full three dimensional patterns into metal surfaces at the pulse rate of the laser, a rate that is at least an order of magnitude faster than competing marking technologies.

  9. Monopoly, Pareto and Ramsey mark-ups

    OpenAIRE

    Ten Raa, T.

    2009-01-01

    Monopoly prices are too high. It is a price level problem, in the sense that the relative mark-ups have Ramsey optimal proportions, at least for independent constant elasticity demands. I show that this feature of monopoly prices breaks down the moment one demand is replaced by the textbook linear demand or, even within the constant elasticity framework, dependence is introduced. The analysis provides a single Generalized Inverse Elasticity Rule for the problems of monopoly, Pareto and Ramsey.

  10. Utilization of Slovenian TRIGA Mark II reactor

    International Nuclear Information System (INIS)

    Snoj, L.; Smodis, B.

    2010-01-01

    TRIGA Mark II research reactor at the Jozef Stefan Institute [JSI] is extensively used for various applications, such as: irradiation of various samples, training and education, verification and validation of nuclear data and computer codes, testing and development of experimental equipment used for core physics tests at a nuclear power plant. The paper briefly describes the aforementioned activities and shows that even such small reactors are still indispensable in nuclear science and technology. (author)

  11. High efficiency metal marking with CO2 laser and glass marking with excimer laser

    DEFF Research Database (Denmark)

    Bastue, Jens; Olsen, Flemmming Ove

    1997-01-01

    with a thoroughly tested ray-tracing model is presented and compared with experimental results. Special emphasis is put on two different applications namely marking in metal with TEA-CO2 laser and marking in glass with excimer laser. The results are evaluated on the basis of the achievable energy enhancement......Today, mask based laser materials processing and especially marking is widely used. However, the energy efficiency in such processes is very low [1].This paper gives a review of the results, that may be obtained using the energy enhancing technique [1]. Results of simulations performed...

  12. The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.

    Science.gov (United States)

    Vandeweyer, Geert; Van der Aa, Nathalie; Reyniers, Edwin; Kooy, R Frank

    2012-06-08

    Williams-Beuren syndrome is a rare contiguous gene syndrome, characterized by intellectual disability, facial dysmorphisms, connective-tissue abnormalities, cardiac defects, structural brain abnormalities, and transient infantile hypercalcemia. Genes lying telomeric to RFC2, including CLIP2, GTF2I and GTF2IRD1, are currently thought to be the most likely major contributors to the typical Williams syndrome cognitive profile, characterized by a better-than-expected auditory rote-memory ability, a relative sparing of language capabilities, and a severe visual-spatial constructive impairment. Atypical deletions in the region have helped to establish genotype-phenotype correlations. So far, however, hardly any deletions affecting only a single gene in the disease region have been described. We present here two healthy siblings with a pure, hemizygous deletion of CLIP2. A putative role in the cognitive and behavioral abnormalities seen in Williams-Beuren patients has been suggested for this gene on the basis of observations in a knock-out mouse model. The presented siblings did not show any of the clinical features associated with the syndrome. Cognitive testing showed an average IQ for both and no indication of the Williams syndrome cognitive profile. This shows that CLIP2 haploinsufficiency by itself does not lead to the physical or cognitive characteristics of the Williams-Beuren syndrome, nor does it lead to the Williams syndrome cognitive profile. Although contribution of CLIP2 to the phenotype cannot be excluded when it is deleted in combination with other genes, our results support the hypothesis that GTF2IRD1 and GTF2I are the main genes causing the cognitive defects associated with Williams-Beuren syndrome. Copyright © 2012 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  13. Mark Raidpere näitused Pariisis ja Napolis / Mark Raidpere ; interv. Harry Liivrand

    Index Scriptorium Estoniae

    Raidpere, Mark

    2008-01-01

    Mark Raidpere videod "Vekovka", "Dedication / Pühendus", "Majestoso Mystico" näitusel Pariisis Michel Reini galeriis. Osaleb koos saksa fotograafi Sven Johnega näitusel Napolis. Kreekas Thessalonikis valminud filmist "1:1:1"

  14. Explicit Oral Narrative Intervention for Students with Williams Syndrome

    Science.gov (United States)

    Diez-Itza, Eliseo; Martínez, Verónica; Pérez, Vanesa; Fernández-Urquiza, Maite

    2018-01-01

    Narrative skills play a crucial role in organizing experience, facilitating social interaction and building academic discourse and literacy. They are at the interface of cognitive, social, and linguistic abilities related to school engagement. Despite their relative strengths in social and grammatical skills, students with Williams syndrome (WS) do not show parallel cognitive and pragmatic performance in narrative generation tasks. The aim of the present study was to assess retelling of a TV cartoon tale and the effect of an individualized explicit instruction of the narrative structure. Participants included eight students with WS who attended different special education levels. Narratives were elicited in two sessions (pre and post intervention), and were transcribed, coded and analyzed using the tools of the CHILDES Project. Narratives were coded for productivity and complexity at the microstructure and macrostructure levels. Microstructure productivity (i.e., length of narratives) included number of utterances, clauses, and tokens. Microstructure complexity included mean length of utterances, lexical diversity and use of discourse markers as cohesive devices. Narrative macrostructure was assessed for textual coherence through the Pragmatic Evaluation Protocol for Speech Corpora (PREP-CORP). Macrostructure productivity and complexity included, respectively, the recall and sequential order of scenarios, episodes, events and characters. A total of four intervention sessions, lasting approximately 20 min, were delivered individually once a week. This brief intervention addressed explicit instruction about the narrative structure and the use of specific discourse markers to improve cohesion of story retellings. Intervention strategies included verbal scaffolding and modeling, conversational context for retelling the story and visual support with pictures printed from the cartoon. Results showed significant changes in WS students’ retelling of the story, both at

  15. Explicit Oral Narrative Intervention for Students with Williams Syndrome

    Directory of Open Access Journals (Sweden)

    Eliseo Diez-Itza

    2018-01-01

    Full Text Available Narrative skills play a crucial role in organizing experience, facilitating social interaction and building academic discourse and literacy. They are at the interface of cognitive, social, and linguistic abilities related to school engagement. Despite their relative strengths in social and grammatical skills, students with Williams syndrome (WS do not show parallel cognitive and pragmatic performance in narrative generation tasks. The aim of the present study was to assess retelling of a TV cartoon tale and the effect of an individualized explicit instruction of the narrative structure. Participants included eight students with WS who attended different special education levels. Narratives were elicited in two sessions (pre and post intervention, and were transcribed, coded and analyzed using the tools of the CHILDES Project. Narratives were coded for productivity and complexity at the microstructure and macrostructure levels. Microstructure productivity (i.e., length of narratives included number of utterances, clauses, and tokens. Microstructure complexity included mean length of utterances, lexical diversity and use of discourse markers as cohesive devices. Narrative macrostructure was assessed for textual coherence through the Pragmatic Evaluation Protocol for Speech Corpora (PREP-CORP. Macrostructure productivity and complexity included, respectively, the recall and sequential order of scenarios, episodes, events and characters. A total of four intervention sessions, lasting approximately 20 min, were delivered individually once a week. This brief intervention addressed explicit instruction about the narrative structure and the use of specific discourse markers to improve cohesion of story retellings. Intervention strategies included verbal scaffolding and modeling, conversational context for retelling the story and visual support with pictures printed from the cartoon. Results showed significant changes in WS students’ retelling of the

  16. Language and emotional abilities in children with Williams syndrome and children with autism spectrum disorder: similarities and differences

    Directory of Open Access Journals (Sweden)

    Lacroix A

    2016-07-01

    Full Text Available Agnès Lacroix,1 Nawelle Famelart,2 Michèle Guidetti2 1Department of Psychology, Center for Research in Psychology, Cognition, and Communication, University of Rennes 2, Rennes, 2CLLE, Université de Toulouse, CNRS, UT2J, France Abstract: Williams syndrome (WS is a genetic disease with a relatively homogeneous profile: relatively well-preserved language, impaired cognitive activities, and hypersociability. Autism spectrum disorder (ASD refers to a group of individuals with impairments in aspects of communication and a particular pattern of language acquisition. Although ASD and WS are polar opposites when it comes to communication abilities (language and emotion and social behavior, comparisons between WS and ASD are still rare in the literature. ASD and WS are both associated with general language and developmental delays. Difficulties in social interaction and general pragmatic difficulties are reported in both ASD and WS, but are more pervasive in ASD. Regarding facial emotion recognition, the two syndromes differ markedly in sensitivity to human faces. Despite the heterogeneity of these two groups, only a few studies with children have paid sufficient attention to participant recruitment and study design. A number of aspects need to be taken into account (eg, small age range, homogeneity of the subgroups, matching with typically developing children if scientific results are to inform the design of intervention programs for children with neurodevelopmental disorders such as ASD and WS. Keywords: neurodevelopmental disorders, facial emotion recognition, linguistic abilities, pragmatic abilities, emotions

  17. Approach to downstream planning for nearshore response and sensitive areas protection outside Prince William Sound, Alaska

    International Nuclear Information System (INIS)

    DeCola, E.G.; Robertson, T.L.; Robertson, R.; Banta, J.

    2004-01-01

    This study assessed the need for an oil spill response plan for downstream coastal communities that could be affected by oil spilled from tankers travelling in Prince William Sound, Alaska. For the purpose of oil spill contingency planning, the State of Alaska has been divided into the Kodiak and Cook Inlet sub-areas that are at risk for downstream impacts from a Prince William Sound oil spill. The 1989 Exxon Valdez oil spill provided an example of a worst-case scenario oil spill from a tanker in Prince William Sound, but the oil spill planning system that has evolved in Alaska does not adequately plan for on oil spill that originates in one sub-area of the state, but impacts other sub-areas in the downstream spill path. This study analyzed the gaps that exist in the current response planning system in the Prince William Sound, Cook Inlet and Kodiak sub-areas. A method was proposed to improve the existing response plans so that emergency response teams are better prepared to manage cross-boundary oil spills originating in Prince William Sound. The proposed method focuses on nearshore response and sensitive areas protection for coastlines and communities that are at risk for oil spills from a tanker travelling the Trans-Alaska Pipeline System (TAPS). 11 refs., 3 figs

  18. Conceptualizing neurodevelopmental disorders through a mechanistic understanding of fragile X syndrome and Williams syndrome.

    Science.gov (United States)

    Fung, Lawrence K; Quintin, Eve-Marie; Haas, Brian W; Reiss, Allan L

    2012-04-01

    The overarching goal of this review is to compare and contrast the cognitive-behavioral features of fragile X syndrome (FraX) and Williams syndrome and to review the putative neural and molecular underpinnings of these features. Information is presented in a framework that provides guiding principles for conceptualizing gene-brain-behavior associations in neurodevelopmental disorders. Abnormalities, in particular cognitive-behavioral domains with similarities in underlying neurodevelopmental correlates, occur in both FraX and Williams syndrome including aberrant frontostriatal pathways leading to executive function deficits, and magnocellular/dorsal visual stream, superior parietal lobe, inferior parietal lobe, and postcentral gyrus abnormalities contributing to deficits in visuospatial function. Compelling cognitive-behavioral and neurodevelopmental contrasts also exist in these two disorders, for example, aberrant amygdala and fusiform cortex structure and function occurring in the context of contrasting social behavioral phenotypes, and temporal cortical and cerebellar abnormalities potentially underlying differences in language function. Abnormal dendritic development is a shared neurodevelopmental morphologic feature between FraX and Williams syndrome. Commonalities in molecular machinery and processes across FraX and Williams syndrome occur as well - microRNAs involved in translational regulation of major synaptic proteins; scaffolding proteins in excitatory synapses; and proteins involved in axonal development. Although the genetic variations leading to FraX and Williams syndrome are different, important similarities and contrasts in the phenotype, neurocircuitry, molecular machinery, and cellular processes in these two disorders allow for a unique approach to conceptualizing gene-brain-behavior links occurring in neurodevelopmental disorders.

  19. Holocene deposition and megathrust splay fault geometries within Prince William Sound, Alaska

    Science.gov (United States)

    Finn, S.; Liberty, L. M.; Haeussler, P. J.; Pratt, T. L.

    2011-12-01

    New high resolution sparker seismic reflection data, in conjunction with reprocessed legacy seismic data, provide the basis for a new fault, fold, and Holocene sediment thickness database for Prince William Sound, Alaska. Additionally, legacy airgun seismic data in Prince William Sound and the Gulf of Alaska tie features on these new sparker data to deeper portions of megathrust splay faults. We correlate regionally extensive bathymetric lineaments within Prince William Sound to megathrust splay faults, such as the ones that ruptured in the 1964 M9.2 earthquake. Lastly, we estimate Holocene sediment thickness within Prince William Sound to better constrain the Holocene fault history throughout the region. We identify three seismic facies related to Holocene, Quaternary, and Tertiary strata that are crosscut by numerous high angle normal faults in the hanging wall of the megathrust splay faults. The crustal-scale seismic reflection profiles show splay faults emerging from 20 km depth between the Yakutat block and North American crust and surfacing as the Hanning Bay and Patton Bay faults. A change in exhumation rates, slip rates, and fault orientation appears near Hinchinbrook that we attribute to differences in subducted slab geometry. Based on our slip rate analysis, we calculate average Holocene displacements of 20 m and 100 m in eastern and western Prince William Sound, respectively. Landward of two splay faults exposed on Montague Island, we observe subsidence, faulting, and landslides that record deformation associated with the 1964 and older megathrust earthquakes.

  20. Report of Some Comets: The Discovery of Uranus and Comets by William, Caroline, and John Herschel

    Science.gov (United States)

    Pasachoff, Jay M.; Olson, R. J. M.

    2011-01-01

    We report on the discovery and drawings of comets by William, Caroline, and John Herschel. The first discovery, by William Herschel, in 1781 from Bath, published in the Philosophical Transactions of the Royal Society with the title "Report of a Comet," turned out to be Uranus, the first planet ever discovered, Mercury through Saturn having been known since antiquity. William's sister Caroline was given duties of sweeping the skies and turned out to be a discoverer of 8 comets in her own right, in addition to keeping William's notes. Caroline's comets were discovered from Slough between 1786 and 1797. In the process, we also discuss original documents from the archives of the Royal Society and of the Royal Astronomical Society. We conclude by showing comet drawings that we have recently attributed to John Herschel, including Halley's Comet from 1836, recently located in the Ransom Center of the University of Texas at Austin. Acknowledgments: Planetary astronomy at Williams College is supported in part by grant NNX08AO50G from NASA Planetary Astronomy. We thank Peter Hingley of the Royal Astronomical Society and Richard Oram of the Harry Ransom Center of The University of Texas at Austin for their assistance.