WorldWideScience

Sample records for widespread research activities

  1. Vitamin D inadequacy is widespread in Tunisian active boys and is ...

    African Journals Online (AJOL)

    Vitamin D inadequacy is widespread in Tunisian active boys and is related to diet but not to adiposity or insulin resistance. Ikram Bezrati, Mohamed Kacem Ben Fradj, Nejmeddine Ouerghi, Moncef Feki, Anis Chaouachi, Naziha Kaabachi ...

  2. Usability of Mobile Phones in Physical Activity-Rrelated Research: A Systematic Review

    Science.gov (United States)

    Monroe, Courtney M.; Thompson, Dixie L.; Bassett, David R., Jr.; Fitzhugh, Eugene C.; Raynor, Hollie A.

    2015-01-01

    Background: The use of mobile phones for physical activity (PA) promotion and assessment represents an attractive research area because this technology is characterized by a widespread reach and dynamic features. Purpose: The purpose of this study was to conduct a systematic review of mobile phone-based approaches for encouraging and assessing PA.…

  3. Thermal Non-equilibrium Consistent with Widespread Cooling

    Science.gov (United States)

    Winebarger, A.; Lionello, R.; Mikic, Z.; Linker, J.; Mok, Y.

    2014-01-01

    Time correlation analysis has been used to show widespread cooling in the solar corona; this cooling has been interpreted as a result of impulsive (nanoflare) heating. In this work, we investigate wide-spread cooling using a 3D model for a solar active region which has been heated with highly stratified heating. This type of heating drives thermal non-equilibrium solutions, meaning that though the heating is effectively steady, the density and temperature in the solution are not. We simulate the expected observations in narrowband EUV images and apply the time correlation analysis. We find that the results of this analysis are qualitatively similar to the observed data. We discuss additional diagnostics that may be applied to differentiate between these two heating scenarios.

  4. Are neonicotinoid insecticides driving declines of widespread butterflies?

    Directory of Open Access Journals (Sweden)

    Andre S. Gilburn

    2015-11-01

    Full Text Available There has been widespread concern that neonicotinoid pesticides may be adversely impacting wild and managed bees for some years, but recently attention has shifted to examining broader effects they may be having on biodiversity. For example in the Netherlands, declines in insectivorous birds are positively associated with levels of neonicotinoid pollution in surface water. In England, the total abundance of widespread butterfly species declined by 58% on farmed land between 2000 and 2009 despite both a doubling in conservation spending in the UK, and predictions that climate change should benefit most species. Here we build models of the UK population indices from 1985 to 2012 for 17 widespread butterfly species that commonly occur at farmland sites. Of the factors we tested, three correlated significantly with butterfly populations. Summer temperature and the index for a species the previous year are both positively associated with butterfly indices. By contrast, the number of hectares of farmland where neonicotinoid pesticides are used is negatively associated with butterfly indices. Indices for 15 of the 17 species show negative associations with neonicotinoid usage. The declines in butterflies have largely occurred in England, where neonicotinoid usage is at its highest. In Scotland, where neonicotinoid usage is comparatively low, butterfly numbers are stable. Further research is needed urgently to show whether there is a causal link between neonicotinoid usage and the decline of widespread butterflies or whether it simply represents a proxy for other environmental factors associated with intensive agriculture.

  5. Microwave Photonics: current challenges towards widespread application.

    Science.gov (United States)

    Capmany, José; Li, Guifang; Lim, Christina; Yao, Jianping

    2013-09-23

    Microwave Photonics, a symbiotic field of research that brings together the worlds of optics and radio frequency is currently facing several challenges in its transition from a niche to a truly widespread technology essential to support the ever-increasing values for speed, bandwidth, processing capability and dynamic range that will be required in next generation hybrid access networks. We outline these challenges, which are the subject of the contributions to this focus issue.

  6. Trace element structure of the most widespread plants of genus PulmonariaFNx01

    Directory of Open Access Journals (Sweden)

    Dmitriy Kruglov

    2012-01-01

    Full Text Available Aim: The aim of this work was a comparative research of trace element structure of various organs of three Pulmonaria species. Materials and Methods: The aerial parts of the most widespread plants of genus Pulmonaria such as Pulmonaria officinalis L., Pulmonaria obscura Dumort. and Pulmonaria mollis Wulf. ex Hornem., which were collected in ending of flowering and were used as the research objects. The amount of trace elements (B, K, P, V, Ca, Co, Cu, Fe, Mg, Mn, Mo, Na, Si, Zn, Ag, Al, Ba, Br, Cr, I, Ni, Se, Sr, and Ti was determined by means of mass spectroscopy with inductively coupled plasma. Results: The data clustering has shown that floral shoots and rosellate leaves possess essentially various trace element status. At the same time, the trace elements′ status of organs of researched plants poorly depends on a taxonomic position of the plant. Thereupon, it is obvious that pharmacological activity is defined by organs of plants from which medicines were made, but not by a species of the used plant. Conclusions: The significant distinction in pharmacological activity of preparations depends on the trace elements′ status of used medicinal vegetative raw materials.

  7. [Application of chemometrics in composition-activity relationship research of traditional Chinese medicine].

    Science.gov (United States)

    Han, Sheng-Nan

    2014-07-01

    Chemometrics is a new branch of chemistry which is widely applied to various fields of analytical chemistry. Chemometrics can use theories and methods of mathematics, statistics, computer science and other related disciplines to optimize the chemical measurement process and maximize access to acquire chemical information and other information on material systems by analyzing chemical measurement data. In recent years, traditional Chinese medicine has attracted widespread attention. In the research of traditional Chinese medicine, it has been a key problem that how to interpret the relationship between various chemical components and its efficacy, which seriously restricts the modernization of Chinese medicine. As chemometrics brings the multivariate analysis methods into the chemical research, it has been applied as an effective research tool in the composition-activity relationship research of Chinese medicine. This article reviews the applications of chemometrics methods in the composition-activity relationship research in recent years. The applications of multivariate statistical analysis methods (such as regression analysis, correlation analysis, principal component analysis, etc. ) and artificial neural network (such as back propagation artificial neural network, radical basis function neural network, support vector machine, etc. ) are summarized, including the brief fundamental principles, the research contents and the advantages and disadvantages. Finally, the existing main problems and prospects of its future researches are proposed.

  8. Widespread Usutu virus outbreak in birds in the Netherlands, 2016

    Science.gov (United States)

    Rijks, JM; Kik, ML; Slaterus, R; Foppen, RPB; Stroo, A; IJzer, J; Stahl, J; Gröne, A; Koopmans, MGP; van der Jeugd, HP; Reusken, CBEM

    2016-01-01

    We report a widespread Usutu virus outbreak in birds in the Netherlands. Viral presence had been detected through targeted surveillance as early as April 2016 and increased mortality in common blackbirds and captive great grey owls was noticed from August 2016 onwards. Usutu virus infection was confirmed by post-mortem examination and RT-PCR. Extensive Usutu virus activity in the Netherlands in 2016 underlines the need to monitor mosquito activity and mosquito-borne infections in 2017 and beyond. PMID:27918257

  9. Widespread occurrence of neuro-active pharmaceuticals and metabolites in 24 Minnesota rivers and wastewaters

    Science.gov (United States)

    Writer, Jeffrey; Ferrer, Imma; Barber, Larry B.; Thurman, E. Michael

    2013-01-01

    Concentrations of 17 neuro-active pharmaceuticals and their major metabolites (bupropion, hydroxy-bupropion, erythro-hydrobupropion, threo-hydrobupropion, carbamazepine, 10,11,-dihydro-10,11,-dihydroxycarbamazepine, 10-hydroxy-carbamazepine, citalopram, N-desmethyl-citalopram, fluoxetine, norfluoxetine, gabapentin, lamotrigine, 2-N-glucuronide-lamotrigine, oxcarbazepine, venlafaxine and O-desmethyl-venlafaxine), were measured in treated wastewater and receiving surface waters from 24 locations across Minnesota, USA. The analysis of upstream and downstream sampling sites indicated that the wastewater treatment plants were the major source of the neuro-active pharmaceuticals and associated metabolites in surface waters of Minnesota. Concentrations of parent compound and the associated metabolite varied substantially between treatment plants (concentrations ± standard deviation of the parent compound relative to its major metabolite) as illustrated by the following examples; bupropion and hydrobupropion 700 ± 1000 ng L−1, 2100 ± 1700 ng L−1, carbamazepine and 10-hydroxy-carbamazepine 480 ± 380 ng L−1, 360 ± 400 ng L−1, venlafaxine and O-desmethyl-venlafaxine 1400 ± 1300 ng L−1, 1800 ± 2300 ng L−1. Metabolites of the neuro-active compounds were commonly found at higher or comparable concentrations to the parent compounds in wastewater effluent and the receiving surface water. Neuro-active pharmaceuticals and associated metabolites were detected only sporadically in samples upstream from the effluent outfall. Metabolite to parent ratios were used to evaluate transformation, and we determined that ratios in wastewater were much lower than those reported in urine, indicating that the metabolites are relatively more labile than the parent compounds in the treatment plants and in receiving waters. The widespread occurrence of neuro-active pharmaceuticals and metabolites in Minnesota effluents and surface waters indicate that

  10. Widespread pain: is an improved classification possible?

    Science.gov (United States)

    MacFarlane, G J; Croft, P R; Schollum, J; Silman, A J

    1996-09-01

    The classification of widespread pain, proposed by the American College of Rheumatology (ACR) for use in the clinic as a screen for fibromyalgia, as described, does not require truly widespread pain. Studies considering the epidemiology of widespread pain per se may therefore require a definition with greater face validity, which might also show enhanced associations with other physical and psychological measures. We aimed to develop a more coherent definition of widespread pain for use in epidemiological studies and to compare performance in identifying individuals with significant morbidity. A group of 172 subjects who had participated in a community based study on the occurrence of pain were identified and categorized by their pain experience as indicated on line drawings of the body according to ACR definition and to a new, more stringent definition that required the presence of more diffuse limb pain. A number of other clinical and psychological measures were recorded for these individuals and the association between their pain status measures and these other variables was assessed and compared. Persons satisfying the newly proposed definition for chronic widespread pain, in comparison with those who satisfied only the present ACR definition, had a significantly higher score on the General Health Questionnaire [median difference (MD) 7.95% CI 1.13], a higher score on the Health and Fatigue Questionnaire (MD 10.95% CI 0.15), and greater problems with sleep (sleep problem score MD 4.95% CI 0.9). Those satisfying the new definition also had a greater number of tender points on examination (MD 3.95% CI -1.7). The morbidity of those satisfying only the present ACR definition was closer to persons who had regional pain. A redefinition of widespread pain has produced a group of subjects whose pain is (a) likely to be more "widespread" and (b) is associated more strongly with factors such as psychological disturbance, fatigue, sleep problems, and tender points, and

  11. Personality disparity in chronic regional and widespread pain.

    Science.gov (United States)

    Chang, Mei-Chung; Chen, Po-Fei; Lung, For-Wey

    2017-08-01

    Chronic pain has high comorbidity with psychiatric disorders, therefore, better understanding of the relationship between chronic pain and mental illness is needed. This study aimed to investigate the pathway relationships among parental attachment, personality characteristics, alexithymic trait and mental health in patients with chronic widespread pain, those with chronic regional pain, and controls. Two hundred and thirty participants were recruited. The parental Bonding Inventory, Eysenck Personality Inventory (EPI), 20-item Toronto Alexithymia Scale (TAS-20), Chinese Health Questionnaire, and Short-Form 36 were filled out. The pathway relationships revealed that patients of mothers who were more protective were more neurotic, had more difficulty identifying feelings (DIF), worse mental health, and a higher association with chronic widespread pain. No differences were found between patients with chronic regional pain and the controls. The predisposing factors for chronic widespread pain, when compared with chronic regional pain, may be more closely related to psychiatric disorders. The pathways to chronic regional pain and chronic widespread pain differ, with neuroticism and the alexithymic DIF trait being the main factors defining chronic widespread pain. Therefore, besides therapies targeting pain symptoms, psychiatric consultation, medication and psychotherapy are also recommended for those with chronic widespread pain to alleviate their mental health conditions. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  12. Performance-based assessment of activities of daily living (ADL) ability among women with chronic widespread pain

    DEFF Research Database (Denmark)

    Wæhrens, Eva Ejlersen; Amris, Kirstine; Fisher, Anne G

    2010-01-01

    . The investigated psychometric properties of the AMPS included discrimination between a sample of healthy women and those with chronic widespread pain, as well as stability when no intervention was provided and sensitivity to change following intervention. Data were obtained based on a repeated measures design......-report and performance-based assessment of ADL offer distinct but complementary information about ability. The present study, therefore, investigated the applicability of a performance-based measure of ADL ability, the Assessment of Motor and Process Skills (AMPS), among 50 women with chronic widespread pain...... performing AMPS evaluations twice pre- and twice post-rehabilitation. Results indicated that the ADL motor ability measures of the participants were significantly lower than those of healthy women of same age, the ADL motor and ADL process ability measures remained stable when no intervention was provided...

  13. Applying ecological concepts to the management of widespread grass invasions [Chapter 7

    Science.gov (United States)

    Carla M. D' Antonio; Jeanne C. Chambers; Rhonda Loh; J. Tim Tunison

    2009-01-01

    The management of plant invasions has typically focused on the removal of invading populations or control of existing widespread species to unspecified but lower levels. Invasive plant management typically has not involved active restoration of background vegetation to reduce the likelihood of invader reestablishment. Here, we argue that land managers could benefit...

  14. Assessment report on research and development activities. Activity: 'Advanced science research' (Interim report)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-11-15

    Japan Atomic Energy Agency (hereinafter referred to as 'JAEA') consulted an assessment committee, 'Evaluation Committee of Research Activities for Advanced Science Research' (hereinafter referred to as 'Committee') for interim assessment of 'Advanced Science Research,' in accordance with 'General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research programs and activities of the Advanced Science Research Center (hereinafter referred to as 'ASRC') for the period of two years from April 2010. The Committee evaluated the management and the research programs of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the result of the assessment by the Committee with the Committee report attached from page 7. (author)

  15. Assessment report of research and development activities. Activity: advanced science research' (Interim report)

    International Nuclear Information System (INIS)

    2008-08-01

    Japan Atomic Energy Agency (hereinafter referred to as 'JAEA') consults an assessment committee, 'Evaluation Committee of Research Activities for Advanced Science Research' (hereinafter referred to as 'Committee') for interim assessment of 'Advanced Science Research,' in accordance with General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research program of the Advanced Science Research Center (hereinafter referred to as 'ASRC') during the period of two years from October 2005 to September 2007. The Committee evaluated the management and research activities of the ASRC based on the explanatory documents prepared by the ASRC, the oral presentations with questions-and-answers by the Director and the research group leaders, and interviews from group members through on-site visits by the Committee members. One CD-ROM is attached as an appendix. (J.P.N.)

  16. How Technology and Collaboration Promote Formative Feedback: A Role for CSCL Research in Active Learning Interventions

    Science.gov (United States)

    Wu, Sally P. W.; Rau, Martina A.

    2017-01-01

    Recent evidence for the effectiveness of active learning interventions has led educators to advocate for widespread adoption of active learning in undergraduate science, technology, engineering, and mathematics courses. Active learning interventions implement technology and collaboration to engage students actively with the content. Yet, it is…

  17. Chronic widespread pain in spondyloarthritis

    Directory of Open Access Journals (Sweden)

    F. Atzeni

    2014-06-01

    Full Text Available The pain associated with spondyloarthritis (SpA can be intense, persistent and disabling. It frequently has a multifactorial, simultaneously central and peripheral origin, and may be due to currently active inflammation, or joint damage and tissue destruction arising from a previous inflammatory condition. Inflammatory pain symptoms can be reduced by non-steroidal anti-inflammatory drugs, but many patients continue to experience moderate pain due to alterations in the mechanisms that regulate central pain, as in the case of the chronic widespread pain (CWP that characterises fibromyalgia (FM. The importance of distinguishing SpA and FM is underlined by the fact that SpA is currently treated with costly drugs such as tumour necrosis factor (TNF inhibitors, and direct costs are higher in patients with concomitant CWP or FM than in those with FM or SpA alone. Optimal treatment needs to take into account symptoms such as fatigue, mood, sleep, and the overall quality of life, and is based on the use of tricyclic antidepressants or selective serotonin reuptake inhibitors such as fluoxetine, rather than adjustments in the dose of anti-TNF agents or disease-modifying drugs.

  18. Local trauma in human patellar tendon leads to widespread changes in the tendon gene expression

    DEFF Research Database (Denmark)

    Heinemeier, Katja Maria; Lorentzen, Marc P; Kildevang Jensen, Jacob

    2016-01-01

    Low cellular activity and slow tissue turnover in human tendon may prolong resolution of tendinopathy. This may be stimulated by moderate localized traumas such as needle penetrations, but whether this results in a widespread cellular response in tendons is unknown. In an initial hypothesis-gener...

  19. Planning and Conducting Research Activities.

    Science.gov (United States)

    Christiansen, Richard L.

    1983-01-01

    Some directions and influences on dental research activities in the near future are discussed. Current challenges include international competition, fellowships, and equipment. Potential research activity includes preventive medicine, epidemiology, chronic illness, the elderly, bioengineering, materials research, nutrition, soft tissue research,…

  20. Assessment report of research and development activities. Activity: 'Advanced science research' (Pre-review report)

    International Nuclear Information System (INIS)

    2010-11-01

    Japan Atomic Energy Agency (hereinafter referred to as 'JAEA') consulted an assessment committee, 'Evaluation Committee of Research Activities for Advanced Science Research' (hereinafter referred to as 'Committee') for prior assessment of 'Advanced Science Research,' in accordance with 'General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research program and activities of the Advanced Science Research Center (hereinafter referred to as 'ASRC') for the period of five years from April 2010. The Committee evaluated the management and the research program of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the result of the assessment by the Committee with the Committee report attached from page 7. (author)

  1. Widespread EEG changes precede focal seizures.

    Directory of Open Access Journals (Sweden)

    Piero Perucca

    Full Text Available The process by which the brain transitions into an epileptic seizure is unknown. In this study, we investigated whether the transition to seizure is associated with changes in brain dynamics detectable in the wideband EEG, and whether differences exist across underlying pathologies. Depth electrode ictal EEG recordings from 40 consecutive patients with pharmacoresistant lesional focal epilepsy were low-pass filtered at 500 Hz and sampled at 2,000 Hz. Predefined EEG sections were selected immediately before (immediate preictal, and 30 seconds before the earliest EEG sign suggestive of seizure activity (baseline. Spectral analysis, visual inspection and discrete wavelet transform were used to detect standard (delta, theta, alpha, beta and gamma and high-frequency bands (ripples and fast ripples. At the group level, each EEG frequency band activity increased significantly from baseline to the immediate preictal section, mostly in a progressive manner and independently of any modification in the state of vigilance. Preictal increases in each frequency band activity were widespread, being observed in the seizure-onset zone and lesional tissue, as well as in remote regions. These changes occurred in all the investigated pathologies (mesial temporal atrophy/sclerosis, local/regional cortical atrophy, and malformations of cortical development, but were more pronounced in mesial temporal atrophy/sclerosis. Our findings indicate that a brain state change with distinctive features, in the form of unidirectional changes across the entire EEG bandwidth, occurs immediately prior to seizure onset. We postulate that these changes might reflect a facilitating state of the brain which enables a susceptible region to generate seizures.

  2. Gas solubilities widespread applications

    CERN Document Server

    Gerrard, William

    1980-01-01

    Gas Solubilities: Widespread Applications discusses several topics concerning the various applications of gas solubilities. The first chapter of the book reviews Henr's law, while the second chapter covers the effect of temperature on gas solubility. The third chapter discusses the various gases used by Horiuti, and the following chapters evaluate the data on sulfur dioxide, chlorine data, and solubility data for hydrogen sulfide. Chapter 7 concerns itself with solubility of radon, thoron, and actinon. Chapter 8 tackles the solubilities of diborane and the gaseous hydrides of groups IV, V, and

  3. On the occurrence of a widespread contamination by herbicides of coral reef biota in French Polynesia.

    Science.gov (United States)

    Salvat, Bernard; Roche, Hélène; Ramade, François

    2016-01-01

    Research has been conducted within the framework of the French Initiative for Coral Reefs (IFRECOR) to assess pesticide pollution levels in the coral reef trophic webs in French Polynesia. Unexpected widespread contamination by herbicides was found in algae, fishes and macro-invertebrates located at various levels of the reef trophic web. Concentrations in organisms investigated were for the majority below the lowest observable effect level and do not pose a dietary risk to native population who subsist on these fish. However, the widespread contamination may affect the reef ecosystem in the future as coral symbiotic algae, Symbidinium sp. (Dinophyta) are particularly sensitive to photosystem II herbicides, particularly the substituted urea and triazine derivatives.

  4. Analysis of the Barriers to Widespread Adoption of Electric Vehicles in Shenzhen China

    Directory of Open Access Journals (Sweden)

    Fa-Ping Wang

    2017-03-01

    Full Text Available China promoted the large-scale adoption of Electric Vehicles (EVs in its 13th five-year plan; however, this target faces many obstacles. This paper analyzes the main barriers to widespread adoption of EVs through a survey in Shenzhen, which has the biggest EVs market share out of China’s major cities. Based on previous research, this paper conducted a new study using 406 approved questionnaires among 500 participants. Our study proposed five hypotheses to examine the main barriers to widespread adoption of EVs. The analysis was conducted using statistical method that included two-way frequency tables, chi-square test, and factor analysis. The results indicated that perception of advantages of EVs and access to recharging EVs remained the main barriers in large-scale penetration. Furthermore, our study revealed that a drop in financial incentives would not cause a significant decline in the future adoption of EVs. The study provides suggestions to car manufacturers and government policy advisors based on our analysis and discussion.

  5. The role of the East Asian active margin in widespread extensional and strike-slip deformation in East Asia

    NARCIS (Netherlands)

    Schellart, Wouter P.; Lister, G. S.

    2005-01-01

    East Asia is a region of widespread deformation, dominated by normal and strike-slip faults. Deformation has been interpreted to result from extrusion tectonics related to the India-Eurasia collision, which started in the Early Eocene. In East and SE China, however, deformation started earlier than

  6. Danish research-active clinical nurses overcome barriers in research utilization.

    Science.gov (United States)

    Adamsen, Lis; Larsen, Kristian; Bjerregaard, Lene; Madsen, Jan K

    2003-03-01

    The aim of this study was to examine whether there was a difference between clinical nurses who were research-active, and clinical nurses who were nonresearch-active in utilization of research. A further aim was to identify the most significant barriers faced by a group of Danish clinical nurses in their use of research. Discrepancy between the improved quality of research results and the lack of implementing them was the starting point for a series of studies which showed the types of barriers clinical nurses found especially cumbersome when applying the research results of other researchers. This study investigates whether the clinical nurses' own engagement in research had any impact on their perception of research utilization. The study had an exploratory and descriptive design. Seventy-nine Danish clinical nurses participated and semi-structured interviewing was used as the research method. There was a statistically significant difference between the research-active and nonresearch-active nurses on various variables. The study showed that, to a larger extent, research-active nurses used evidence-based knowledge and were generally more internationally orientated. Furthermore, two important barriers for research utilization were identified by all 79 clinical nurses included in the study, i.e. 90% of the nurses explained that the quantity of research results was overwhelming, and 75% of them found that they were unable to evaluate the quality of the research. Clinical nurses, who were research-active themselves, experienced more success in overcoming some of the barriers, which existed in applying research to practice. The research potential found amongst clinical nurses in Denmark needed to be further supported through training and guidance in research methodology, establishing introductory stipends and part-time research positions. By doing so, some of the barriers affecting research utilization and the so-called theory-practice gap might be reduced. Further

  7. Activities as a research resource

    Directory of Open Access Journals (Sweden)

    Carla Regina Silva

    2013-12-01

    Full Text Available Activities play a guiding central role in occupational therapy, articulating to its utilization, the understanding and assessment of its capabilities in numerous and different interventions arising from this field. In this study, we aim to present the use of activities as a research methodology resource. Considering the pathways studied in a master’s research followed by a PhD work, some applications of this resource are reported as a powerful strategy of investigation for the occupational therapy researcher. It is about structuring, systematizing, and analyzing the activities proposed in professional practice by the theoretical and methodological rigor used in the research works. It emphasizes how the use of these activities can be considered important data, records, instruments and sources for different research methods, especially for qualitative analyses. Workshop activities were offered in the above mentioned studies; they were used as communication instruments and expressions of personal and collective experiences, supplying data to understand the actions of subjects and collectives. Furthermore, this strategy was applied as spaces of experimentation, learning and expression, where each participant was conceived as an active being of the process, in a way that the proposal could result in democratic experiences that reflected greater interest and participation, and a more complex presentation of the research data. It is worth mentioning that other methodological procedures, which substantiated the analyses and interpretation of the data collected, were also used. It was possible to conclude that activities, mainly as a qualitative research resource, constituted materialities in different languages and expressions that enriched the analyses arising from micro-realities, producing a repertoire of information that supported the interpretations required for the investigative processes.

  8. A case for clean conferences in gambling research.

    Science.gov (United States)

    Livingstone, Charles

    2018-02-14

    Gambling research is characterised by widespread gambling industry involvement. It is likely (as with alcohol and tobacco industry influence) that this will delay or divert effective harm prevention or minimisation measures. Gambling harms are known to be significant and widespread. Effective action to reduce these harms requires concomitant efforts to eliminate industry influence. Gambling industry influence and activity in three research forums is described. The influence of tobacco and alcohol industry involvement in research directions and outcomes is discussed. Aspects of the discursive elements of industry funded and/or directed research outputs are analysed in the context of industry-friendly discourse and its effects. Industry activity and participation at representative research forums is outlined. The examples and background provided demonstrate that specific material and discursive effects of gambling industry involvement can be discerned in the gambling literature. The consequences of this for the gambling evidence base around harm prevention and minimisation are presented. Industry influence operates at multiple levels within the gambling research field. There is increasing awareness of this, and of the effects it may have on the development and deployment of effective harm prevention and minimisation efforts. Key reforms are proposed: (i) the elimination of industry participation and sponsorship of gambling research associations and forums; and (ii) the establishment where necessary of new research forums and international scholarly associations. © 2018 Australasian Professional Society on Alcohol and other Drugs.

  9. Registered report: Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors2

    OpenAIRE

    sprotocols

    2015-01-01

    Authors: Edward Greenfield, Erin Griner, The Reproducibility Project: Cancer Biology† ### Abstract The [Reproducibility Project: Cancer Biology](https://osf.io/e81xl/wiki/home/) seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012. This Registered Report describes the proposed replication plan of key experiments from “Widespread potential for growth-factor-d...

  10. An Integrated Extravehicular Activity Research Plan

    Science.gov (United States)

    Abercromby, Andrew F. J.; Ross, Amy J.; Cupples, J. Scott

    2016-01-01

    Multiple organizations within NASA and outside of NASA fund and participate in research related to extravehicular activity (EVA). In October 2015, representatives of the EVA Office, the Crew and Thermal Systems Division (CTSD), and the Human Research Program (HRP) at NASA Johnson Space Center agreed on a formal framework to improve multi-year coordination and collaboration in EVA research. At the core of the framework is an Integrated EVA Research Plan and a process by which it will be annually reviewed and updated. The over-arching objective of the collaborative framework is to conduct multi-disciplinary cost-effective research that will enable humans to perform EVAs safely, effectively, comfortably, and efficiently, as needed to enable and enhance human space exploration missions. Research activities must be defined, prioritized, planned and executed to comprehensively address the right questions, avoid duplication, leverage other complementary activities where possible, and ultimately provide actionable evidence-based results in time to inform subsequent tests, developments and/or research activities. Representation of all appropriate stakeholders in the definition, prioritization, planning and execution of research activities is essential to accomplishing the over-arching objective. A formal review of the Integrated EVA Research Plan will be conducted annually. External peer review of all HRP EVA research activities including compilation and review of published literature in the EVA Evidence Book is already performed annually. Coordination with stakeholders outside of the EVA Office, CTSD, and HRP is already in effect on a study-by-study basis; closer coordination on multi-year planning with other EVA stakeholders including academia is being actively pursued. Details of the current Integrated EVA Research Plan are presented including description of ongoing and planned research activities in the areas of: Benchmarking; Anthropometry and Suit Fit; Sensors; Human

  11. Is temporomandibular pain in chronic whiplash-associated disorders part of a more widespread pain syndrome?

    Science.gov (United States)

    Visscher, Corine; Hofman, Nico; Mes, Carola; Lousberg, Richel; Naeije, Machiel

    2005-01-01

    The prevalence of temporomandibular disorders in patients with chronic whiplash-associated disorder is a controversial issue that may be influenced by the widespread pain character and psychologic distress frequently observed in patients with chronic pain. The aim of this study was to determine the prevalence of temporomandibular disorder pain, widespread pain, and psychologic distress in persons with chronic whiplash-associated disorder pain, using a controlled, single blind study design. The prevalence of temporomandibular disorder pain in the chronic whiplash-associated disorder pain group was compared with 2 control groups: a chronic neck pain group and a no neck pain group. From 65 persons, a standardized oral history was taken, a physical examination of the neck and the masticatory system was performed, widespread pain was investigated by tender point palpation, and psychologic distress was measured with a questionnaire (SCL-90). Because the recognition of temporomandibular disorder pain and neck pain remains a matter of debate, 3 well-defined classification systems were used: one based on the oral history, a second on a combination of oral history and pain on active movements and palpation, and a third one based on a combination of oral history and function tests. Irrespective of the classification system used, the chronic whiplash-associated disorder pain group more often suffered from temporomandibular disorder pain (0.001neck pain group. Moreover, patients with whiplash-associated disorder showed more psychologic distress (0.000disorder suggests that the higher prevalence of temporomandibular disorder pain in these patients is part of a more widespread chronic pain disorder.

  12. Research nurse manager perceptions about research activities performed by non-nurse clinical research coordinators.

    Science.gov (United States)

    Jones, Carolynn Thomas; Hastings, Clare; Wilson, Lynda Law

    2015-01-01

    There has been limited research to document differences in roles between nurses and non-nurses who assume clinical research coordination and management roles. Several authors have suggested that there is no acknowledged guidance for the licensure requirements for research study coordinators and that some non-nurse research coordinators may be assuming roles that are outside of their legal scopes of practice. There is a need for further research on issues related to the delegation of clinical research activities to non-nurses. This study used nominal group process focus groups to identify perceptions of experienced research nurse managers at an academic health science center in the Southern United States about the clinical research activities that are being performed by non-nurse clinical research coordinators without supervision that they believed should only be performed by a nurse or under the supervision of a nurse. A total of 13 research nurse managers volunteered to be contacted about the study. Of those, 8 participated in two separate nominal group process focus group sessions. The group members initially identified 22 activities that they felt should only be performed by a nurse or under the direct supervision of a nurse. After discussion and clarification of results, activities were combined into 12 categories of clinical research activities that participants believed should only be performed by a nurse or under the direct supervision of a nurse. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Widespread marrow necrosis during pregnancy

    International Nuclear Information System (INIS)

    Knickerbocker, W.J.; Quenville, N.F.

    1982-01-01

    Recently, a 22-year-old Caucasian female was referred to our Hospital two days post-partum. She had been feeling unwell during the last few days of her pregnancy and complained of multiple aches and pains, worst in the abdomen and lower back. Her admission platelet count was severely depressed and a bone biopsy showed extensive marrow necrosis with viable bony trabeculae. There was no evidence of vasculitis, vascular thrombosis, or malignancy. Widespread marrow necrosis in pregnancy followed by recovery, to our knowledge, has not been previously reported. (orig.)

  14. Assessment report on research and development activities. Activity: 'Advanced science research' (Interim report)

    International Nuclear Information System (INIS)

    2012-11-01

    Japan Atomic Energy Agency (hereinafter referred to as “JAEA”) consulted an assessment committee, “Evaluation Committee of Research Activities for Advanced Science Research” (hereinafter referred to as “Committee”) for interim assessment of “Advanced Science Research,” in accordance with “General Guideline for the Evaluation of Government Research and Development (R and D) Activities” by Cabinet Office, Government of Japan, “Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology” and “Regulation on Conduct for Evaluation of R and D Activities” by JAEA. In response to the JAEA's request, the Committee assessed the research programs and activities of the Advanced Science Research Center (hereinafter referred to as “ASRC”) for the period of two years from April 2010. The Committee evaluated the management and the research programs of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the result of the assessment by the Committee with the Committee report attached from page 7. (author)

  15. Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo.

    Science.gov (United States)

    Maag, Jesper L V; Kaczorowski, Dominik C; Panja, Debabrata; Peters, Timothy J; Bramham, Clive R; Wibrand, Karin; Dinger, Marcel E

    2017-03-23

    DNA methylation is a key modulator of gene expression in mammalian development and cellular differentiation, including neurons. To date, the role of DNA modifications in long-term potentiation (LTP) has not been explored. To investigate the occurrence of DNA methylation changes in LTP, we undertook the first detailed study to describe the methylation status of all known LTP-associated genes during LTP induction in the dentate gyrus of live rats. Using a methylated DNA immunoprecipitation (MeDIP)-array, together with previously published matched RNA-seq and public histone modification data, we discover widespread changes in methylation status of LTP-genes. We further show that the expression of many LTP-genes is correlated with their methylation status. We show that these correlated genes are enriched for RNA-processing, active histone marks, and specific transcription factors. These data reveal that the synaptic activity-evoked methylation changes correlates with pre-existing activation of the chromatin landscape. Finally, we show that methylation of Brain-derived neurotrophic factor (Bdnf) CpG-islands correlates with isoform switching from transcripts containing exon IV to exon I. Together, these data provide the first evidence of widespread regulation of methylation status in LTP-associated genes.

  16. Sustainable Transportation: Accelerating Widespread Adoption of Energy Efficient Vehicles & Fuels (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2014-12-01

    While energy efficient transportation strategies have the potential to simultaneously slash oil consumption and reduce greenhouse gas (GHG) emissions, a truly sustainable solution will require more than just putting drivers behind the wheels of new fuel-efficient cars. As the only national laboratory dedicated 100% to renewable energy and energy efficiency, the National Renewable Energy Laboratory (NREL) accelerates widespread adoption of high-performance, low-emission, energy-efficient passenger and freight vehicles, as well as alternative fuels and related infrastructure. Researchers collaborate closely with industry, government, and research partners, using a whole-systems approach to design better batteries, drivetrains, and engines, as well as thermal management, energy storage, power electronic, climate control, alternative fuel, combustion, and emission systems. NREL's sustainable transportation research, development, and deployment (RD&D) efforts are not limited to vehicles, roads, and fueling stations. The lab also explores ways to save energy and reduce GHGs by integrating transportation technology advancements with renewable energy generation, power grids and building systems, urban planning and policy, and fleet operations.

  17. After the Workshop: A Case Study of Post-Workshop Implementation of Active Learning in an Electrical Engineering Course

    Science.gov (United States)

    Shekhar, Prateek; Maura Borrego

    2017-01-01

    Engineering education research has empirically validated the effectiveness of active learning over traditional instructional methods. However, the dissemination of education research into instructional practice has been slow. Faculty workshops for current and future instructors offer a solution to promote the widespread adoption of active learning…

  18. Performance-based assessment of activities of daily living (ADL) ability among women with chronic widespread pain

    DEFF Research Database (Denmark)

    Wæhrens, Eva Elisabet Ejlersen; Amris, Kirstine; Fisher, Anne G

    2010-01-01

    Functional ability, including the ability to perform activities of daily living (ADL), is considered a core outcome domain in chronic pain clinical trials and is usually assessed through generic or disease-specific self-report questionnaires. Research, however, indicates that self...

  19. Assessment report of research and development activities FY2014. Activity: 'Advanced science research' (Final report)

    International Nuclear Information System (INIS)

    2015-09-01

    Japan Atomic Energy Agency (hereinafter referred to as 'JAEA') consulted an assessment committee, 'Evaluation Committee of Research Activities for Advanced Science Research' (hereinafter referred to as 'Committee') for final evaluation and prior assessment of 'Advanced Science Research,' in accordance with 'General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research programs and activities of the Advanced Science Research Center (hereinafter referred to as 'ASRC') for the period of five years from April 2010 and the research programs from April 2015. The Committee evaluated the management and the research programs of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the results of the assessment by the Committee with the Committee report attached. (author)

  20. IAEA activities on research reactor safety

    International Nuclear Information System (INIS)

    Alcala-Ruiz, F.

    1995-01-01

    Since its inception in 1957, the International Atomic Energy Agency (IAEA) has included activities in its programme to address aspects of research reactors such as safety, utilization and fuel cycle considerations. These activities were based on statutory functions and responsibilities, and on the current situation of research reactors in operation around the world; they responded to IAEA Member States' general or specific demands. At present, the IAEA activities on research reactors cover the above aspects and respond to specific and current issues, amongst which safety-related are of major concern to Member States. The present IAEA Research Reactor Safety Programme (RRSP) is a response to the current situation of about 300 research reactors in operation in 59 countries around the world. (orig.)

  1. Developing a Scenario for widespread use: Best practices, lessons learned

    Science.gov (United States)

    Perry, S.; Jones, L.; Cox, D.

    2011-01-01

    The ShakeOut Scenario is probably the most widely known and used earthquake scenario created to date. Much of the credit for its widespread dissemination and application lies with scenario development criteria that focused on the needs and involvement of end users and with a suite of products that tailored communication of the results to varied end users, who ranged from emergency managers to the general public, from corporations to grassroots organizations. Products were most effective when they were highly visual, when they emphasized the findings of social scientists, and when they communicated the experience of living through the earthquake. This paper summarizes the development criteria and the products that made the ShakeOut Scenario so widely known and used, and it provides some suggestions for future improvements. ?? 2011, Earthquake Engineering Research Institute.

  2. Antiviral Drug Research Proposal Activity

    Directory of Open Access Journals (Sweden)

    Lisa Injaian

    2011-03-01

    Full Text Available The development of antiviral drugs provides an excellent example of how basic and clinical research must be used together in order to achieve the final goal of treating disease. A Research Oriented Learning Activity was designed to help students to better understand how basic and clinical research can be combined toward a common goal. Through this project students gained a better understanding of the process of scientific research and increased their information literacy in the field of virology. The students worked as teams to research the many aspects involved in the antiviral drug design process, with each student becoming an "expert" in one aspect of the project. The Antiviral Drug Research Proposal (ADRP culminated with students presenting their proposals to their peers and local virologists in a poster session. Assessment data showed increased student awareness and knowledge of the research process and the steps involved in the development of antiviral drugs as a result of this activity.

  3. Effects of chronic widespread pain on the health status and quality of life of women after breast cancer surgery

    Directory of Open Access Journals (Sweden)

    Jones Kim D

    2005-04-01

    Full Text Available Abstract Background Most research and treatment of post-breast cancer chronic pain has focused on local or regional pain problems in the operated area. The purpose of this pilot study was to compare and contrast the pain characteristics, symptom impact, health status, and quality of life of post-breast cancer surgery women with regional chronic pain versus those with widespread chronic pain. Methods A cross-sectional, descriptive design compared two groups of women with chronic pain that began after surgery: regional pain (n = 11 and widespread pain (n = 12. Demographics, characteristics of the surgery, as well as standardized questionnaires that measured pain (Brief Pain Inventory (BPI, Short Form McGill Pain Questionnaire (MPQ-SF, disease impact (Fibromyalgia Impact Questionnaire (FIQ, Functional Assessment of Cancer Therapy-Breast (FACT-B, health status (Medical Outcomes Short Form (SF-36 and quality of life (Quality of Life Scale (QOLS were gathered. Results There were no significant differences between the groups on any demographic or type of surgery variable. A majority of both groups described their pain as aching, tender, and sharp on the MPQ-SF. On the BPI, intensity of pain and pain interference were significantly higher in the widespread pain group. Differences between the two groups reached statistical significance on the FIQ total score as well as the FACT-B physical well-being, emotional well-being and breast concerns subscales. The SF-36 physical function, physical role, and body pain subscales were significantly lower in the widespread pain group. QOLS scores were lower in the widespread pain group, but did not reach statistical significance. Conclusion This preliminary work suggests that the women in this study who experienced widespread pain after breast cancer surgery had significantly more severity of pain, pain impact and lower physical health status than those with regional pain.

  4. Activities report of PTT Research

    Science.gov (United States)

    In the field of postal infrastructure research, activities were performed on postcode readers, radiolabels, and techniques of operations research and artificial intelligence. In the field of telecommunication, transportation, and information, research was made on multipurpose coding schemes, speech recognition, hypertext, a multimedia information server, security of electronic data interchange, document retrieval, improvement of the quality of user interfaces, domotics living support (techniques), and standardization of telecommunication prototcols. In the field of telecommunication infrastructure and provisions research, activities were performed on universal personal telecommunications, advanced broadband network technologies, coherent techniques, measurement of audio quality, near field facilities, local beam communication, local area networks, network security, coupling of broadband and narrowband integrated services digital networks, digital mapping, and standardization of protocols.

  5. Science Forum of the renewables 2004: Networked knowledge for renewable energies - Research, development and education - Basis for wide-spread deployment of renewable energies. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Wienges, S.; Stadermann, G.; Szczepanski, P. (eds.)

    2004-09-01

    Energy was one of five foci of the World Summit on Sustainable Development (WSSD) in Johannesburg in 2002. While the access to modern energy is crucial for poverty reduction in particular and development in general, the way of producing and providing that energy is as crucial for environmental and social sustainability. Hence, the renewables 2004 - the International Conference for Renewable Energies was the logical consequence and next step on the way forward. It was held from 1st June to 4th June 2004 in Bonn, Germany, and turned out to be a forum for stakeholders from all sectors: Governments as well as parliamentarians, the private sector, NGOs, International Organisations, and International Financial Institutions. On 1st June this multisectoral approach to the dissemination of renewables was completed by the Science Forum - Education, Research, and Training: Basis for Wide-spread Deployment of Renewable Energies. This one-day side-event brought together scientists and practitioners from allover the world, discussing the future requirements of research and development as well as needs and potentials of education and training for renewables in developing and industrialized countries. (orig.)

  6. Assessment report of research and development activities. Activity: 'Nuclear science and engineering research' (Interim report)

    International Nuclear Information System (INIS)

    2013-11-01

    Japan Atomic Energy Agency (hereinafter referred to as 'JAEA') consults an assessment committee, 'Evaluation Committee of Research Activities for Nuclear Science and Engineering' (hereinafter referred to as 'Committee') for interim assessment of 'Nuclear Science and Engineering,' in accordance with 'General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by the JAEA. In response to the JAEA's request, the Committee assessed the research program of the Nuclear Science and Engineering Directorate (hereinafter referred to as 'NSED') and Center for Computational Science and e-Systems (hereinafter referred to as 'CCSE') during the period of about four years from September 2008 to September 2012. The Committee evaluated the management and research activities of the NSED and the CCSE based on explanatory documents prepared by the NSED and the CCSE, and oral presentations with questions-and-answers by unit managers etc. A CD-ROM is attached as an appendix. (J.P.N.)

  7. Interdisciplinary rehabilitation of patients with chronic widespread pain:

    DEFF Research Database (Denmark)

    Amris, Kirstine; Wæhrens, Eva E; Christensen, Robin

    2014-01-01

    This study examined the functional and psychological outcomes of a 2-week, group-based multicomponent treatment course that targeted patients with chronic widespread pain. Patients (192 included in the intention-to-treat population), all fulfilling the 1990 American College of Rheumatology...

  8. Preparing for Portfolio Careers in Australian Music: Setting a Research Agenda

    Science.gov (United States)

    Bartleet, Brydie-Leigh; Bennett, Dawn; Bridgstock, Ruth; Draper, Paul; Harrison, Scott; Schippers, Huib

    2012-01-01

    In the twenty-first century, Australian musicians increasingly maintain "portfolio" careers, in which they combine diverse employment arrangements and activities. Often, these incorporate industry sectors outside of music. This career pattern is widespread but not well understood, largely because of the limitations of existing research.…

  9. Research-active clinical nurses: against all odds.

    Science.gov (United States)

    Siedlecki, Sandra L; Albert, Nancy M

    2017-03-01

    To develop a theoretical understanding of factors that impact decisions of clinical nurses to conduct a research study. Only a small percentage of all nurses are research-active and even fewer clinical nurses are research-active. Several researchers have explored barriers to research activity by clinical nurses, but few have examined why, in spite of all odds, some clinical nurses are research-active. As the purpose of this study was to develop a theoretical understanding of the research-active nurse, a grounded theory approach was used. The sample interviewed for this study consisted of registered nurses (n = 26) who worked in a hospital or ambulatory setting, had daily direct patient contact and had participated as principal investigator on at least one completed clinical nursing research study that was not in fulfilment of an educational requirement. The interviews were digitally recorded and analysed by two researchers using the constant comparative method. The findings from this study suggest that the conduct of research by clinical nurses was the direct result of a clinical trigger, characteristics and beliefs of the nurse about research and their role in generating knowledge, and the presence of support conditions, such as a research mentor. Clinical nurses can and do conduct research, in spite of constraints due to a lack of time, money and/or knowledge, if they have access to research mentors and are practising in a research-supportive environment. Nurses at the bedside are in a unique position to identify problems most in need of solutions. Findings from this study provide a foundation upon which to develop and test various programmes that seek to increase the number of clinical nurses who are research-active. © 2016 John Wiley & Sons Ltd.

  10. Intra-arterial cis-diamminedichloroplatinum infusion treatment for widespread hepatocellular carcinoma

    International Nuclear Information System (INIS)

    Park, Sung Il; Yang, Hee Chul; Lee, Do Yon; Shim, Yong Woon; Kim, Sang Heum; Kim, Myeong Jin; Lee, Jong Tae; Yoo, Hyung Sik

    1997-01-01

    The purpose of this study is to evaluate the therapeutic efficacy of intra-arterial infusion of Cis-diamminedichloroplatinum (C-DDP) for the treatment of hepatocellular carcinomas with widespread involvement. We retrospectively analyzed 22 patients who between July 1994 and June 1996 had undergone intra-arterial c-DDP infusion therapy for the treatment of hepatocellular carcinomas with widespread involvement. The hepatomas involved both lobes in ten, portal venous obstructions in fourteen, arterio-portal shunts in nine, and arterio-venous shunts in two. Proper hepatic artery was selected for infusion of 100 mg/BSA of C-DDP. The same procedure was repeated every 3 to 4 weeks, and the total number of infusions was 65. On the basis of WHO criteria, response was classified as complete remission, partial remission, stable, or progression of the disease. Six-month and one-year survival rates were estimated, and adverse reactions were evaluated. Although the response rate is not high, intra-arterial C-DDP infusion therapy can be used as an alternative treatment for hepatocellular carcinomas with widespread involvement; adverse reactions are tolerable. (author). 16 refs., 3 figs

  11. isoenzyme analysis of five endemic and one widespread kniphofia ...

    African Journals Online (AJOL)

    Preferred Customer

    ISOENZYME ANALYSIS OF FIVE ENDEMIC AND ONE WIDESPREAD ... plants. The over all mean inbreeding coefficient (F) was positive indicating slight deficiency in the number of ...... populations, indicates rather recent speciation.

  12. Thinking critically about the occurrence of widespread participation in poor nursing care.

    Science.gov (United States)

    Roberts, Marc; Ion, Robin

    2015-04-01

    A discussion of how Arendt's work can be productively re-contextualized to provide a critical analysis of the occurrence of widespread participation in poor nursing care and what the implications of this are for the providers of nursing education. While the recent participation of nurses in healthcare failings, such as that detailed in the Francis report, has been universally condemned, there has been an absence of critical analyses in the literature that attempt to understand the occurrence of such widespread participation in poor nursing care. This is a significant omission in so far as such analyses will form an integral part of the strategy to limit the occurrence of such widespread participation of nurses in future healthcare failings. Discussion paper. Arendt's 'Eichmann in Jerusalem: A Report on the Banality of Evil' and 'Thinking and Moral Considerations: A Lecture'. In addition, a literature search was conducted and articles published in English relating to the terms care, compassion, ethics, judgement and thinking between 2004-2014 were included. It is anticipated that this discussion will stimulate further critical debate about the role of Arendt's work for an understanding of the occurrence of poor nursing care, and encouraging additional detailed analyses of the widespread participation of nurses in healthcare failings more generally. This article provides a challenging analysis of the widespread participation of nurses in poor care and discusses the opportunities confronting the providers of nursing education in limiting future healthcare failings. © 2014 John Wiley & Sons Ltd.

  13. Ultraviolet vision may be widespread in bats

    Science.gov (United States)

    Gorresen, P. Marcos; Cryan, Paul; Dalton, David C.; Wolf, Sandy; Bonaccorso, Frank

    2015-01-01

    Insectivorous bats are well known for their abilities to find and pursue flying insect prey at close range using echolocation, but they also rely heavily on vision. For example, at night bats use vision to orient across landscapes, avoid large obstacles, and locate roosts. Although lacking sharp visual acuity, the eyes of bats evolved to function at very low levels of illumination. Recent evidence based on genetics, immunohistochemistry, and laboratory behavioral trials indicated that many bats can see ultraviolet light (UV), at least at illumination levels similar to or brighter than those before twilight. Despite this growing evidence for potentially widespread UV vision in bats, the prevalence of UV vision among bats remains unknown and has not been studied outside of the laboratory. We used a Y-maze to test whether wild-caught bats could see reflected UV light and whether such UV vision functions at the dim lighting conditions typically experienced by night-flying bats. Seven insectivorous species of bats, representing five genera and three families, showed a statistically significant ‘escape-toward-the-light’ behavior when placed in the Y-maze. Our results provide compelling evidence of widespread dim-light UV vision in bats.

  14. Activities of the research committee

    Energy Technology Data Exchange (ETDEWEB)

    Hasegawa, A.; Shirai, T.; Nakagawa, M.; Osugi, T.; Ikeda, Y.; Ishida, T.; Shimazaki, J. [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2000-01-01

    The department of Nuclear Energy System serves as a secretarial of the following four research committees organized by JAERI; Japanese Nuclear Data Committee, Atomic and Molecular Data Research Committee, Research Committee on Reactor Physics and Research Committee on Marine Reactors. The purpose and the expected task of each committee are summarized here. The detailed activities of each committee are presented in this paper. (author)

  15. Intelligence in childhood and chronic widespread pain in middle age: the National Child Development Survey.

    Science.gov (United States)

    Gale, Catharine R; Deary, Ian J; Cooper, Cyrus; Batty, G David

    2012-12-01

    Psychological factors are thought to play a part in the aetiology of chronic widespread pain. We investigated the relationship between intelligence in childhood and risk of chronic widespread pain in adulthood in 6902 men and women from the National Child Development Survey (1958 British Birth Cohort). Participants took a test of general cognitive ability at age 11 years; and chronic widespread pain, defined according to the American College of Rheumatology criteria, was assessed at age 45 years. Risk ratios (RRs) and 95% confidence intervals (CIs) were estimated using log-binomial regression, adjusting for sex and potential confounding or mediating factors. Risk of chronic widespread pain, defined according to the American College of Rheumatology criteria, rose in a stepwise fashion as intelligence fell (P for linear trend intelligence quotient, the RR of chronic widespread pain was 1.26 (95% CI 1.17-1.35). In multivariate backwards stepwise regression, lower childhood intelligence remained as an independent predictor of chronic widespread pain (RR 1.10; 95% CI 1.01-1.19), along with social class, educational attainment, body mass index, smoking status, and psychological distress. Part of the effect of lower childhood intelligence on risk of chronic widespread pain in midlife was significantly mediated through greater body mass index and more disadvantaged socioeconomic position. Men and women with higher intelligence in childhood are less likely as adults to report chronic widespread pain. Copyright © 2012 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

  16. Enhanced Memory as a Common Effect of Active Learning

    Science.gov (United States)

    Markant, Douglas B.; Ruggeri, Azzurra; Gureckis, Todd M.; Xu, Fei

    2016-01-01

    Despite widespread consensus among educators that "active learning" leads to better outcomes than comparatively passive forms of instruction, it is often unclear why these benefits arise. In this article, we review research showing that the opportunity to control the information experienced while learning leads to improved memory…

  17. Association of chronic widespread pain with objectively measured physical activity in adults: findings from the National Health and Nutrition Examination survey.

    Science.gov (United States)

    Dansie, Elizabeth J; Turk, Dennis C; Martin, Kathryn R; Van Domelen, Dane R; Patel, Kushang V

    2014-05-01

    Chronic widespread pain (CWP) is a common and potentially debilitating disorder. Patterns of physical activity (PA) in adults with CWP have primarily been investigated using subjective, self-report measures. The current study sought to characterize PA among community-dwelling individuals with CWP, chronic regional pain, or no chronic pain using objective measurements obtained via accelerometry in the 2003 to 2004 National Health and Nutrition Examination Survey. Data from 3,952 participants ages 20 and older were analyzed to assess relationships between pain status and objective measurements of PA. Prevalence of CWP was 3.3% and 5.4% in men and women, respectively. In men and women, the average activity counts per minute and time spent in moderate-to-vigorous PA were significantly lower for the CWP group than for the no chronic pain group. Interestingly, time spent in sedentary, light, and lifestyle activities was not associated with pain status. Statistical interaction tests indicated that the effects of chronic pain on counts per minute were stronger in men than in women. Despite recommendations for increased moderate-to-vigorous PA as a pain management strategy for CWP, results from this nationally representative study indicate that adults with CWP participate in less moderate-to-vigorous PA than individuals without chronic pain. Using objective measurement of PA in a nationally representative sample, this study demonstrates that adults with CWP participate in reduced daily and moderate-to-vigorous PA in comparison to people with no chronic pain. Findings indicate that clinicians should emphasize the importance of increasing PA in patients with CWP. Copyright © 2014 American Pain Society. Published by Elsevier Inc. All rights reserved.

  18. Widespread plant species: natives vs. aliens in our changing world

    Science.gov (United States)

    Stohlgren, Thomas J.; Pyšek, Petr; Kartesz, John; Nishino, Misako; Pauchard, Aníbal; Winter, Marten; Pino, Joan; Richardson, David M.; Wilson, John R.U.; Murray, Brad R.; Phillips, Megan L.; Ming-yang, Li; Celesti-Grapow, Laura; Font, Xavier

    2011-01-01

    Estimates of the level of invasion for a region are traditionally based on relative numbers of native and alien species. However, alien species differ dramatically in the size of their invasive ranges. Here we present the first study to quantify the level of invasion for several regions of the world in terms of the most widely distributed plant species (natives vs. aliens). Aliens accounted for 51.3% of the 120 most widely distributed plant species in North America, 43.3% in New South Wales (Australia), 34.2% in Chile, 29.7% in Argentina, and 22.5% in the Republic of South Africa. However, Europe had only 1% of alien species among the most widespread species of the flora. Across regions, alien species relative to native species were either as well-distributed (10 comparisons) or more widely distributed (5 comparisons). These striking patterns highlight the profound contribution that widespread invasive alien plants make to floristic dominance patterns across different regions. Many of the most widespread species are alien plants, and, in particular, Europe and Asia appear as major contributors to the homogenization of the floras in the Americas. We recommend that spatial extent of invasion should be explicitly incorporated in assessments of invasibility, globalization, and risk assessments.

  19. Widespread plant species: Natives versus aliens in our changing world

    Science.gov (United States)

    Stohlgren, T.J.; Pysek, P.; Kartesz, J.; Nishino, M.; Pauchard, A.; Winter, M.; Pino, J.; Richardson, D.M.; Wilson, J.R.U.; Murray, B.R.; Phillips, M.L.; Ming-yang, L.; Celesti-Grapow, L.; Font, X.

    2011-01-01

    Estimates of the level of invasion for a region are traditionally based on relative numbers of native and alien species. However, alien species differ dramatically in the size of their invasive ranges. Here we present the first study to quantify the level of invasion for several regions of the world in terms of the most widely distributed plant species (natives vs. aliens). Aliens accounted for 51.3% of the 120 most widely distributed plant species in North America, 43.3% in New South Wales (Australia), 34.2% in Chile, 29.7% in Argentina, and 22.5% in the Republic of South Africa. However, Europe had only 1% of alien species among the most widespread species of the flora. Across regions, alien species relative to native species were either as well-distributed (10 comparisons) or more widely distributed (5 comparisons). These striking patterns highlight the profound contribution that widespread invasive alien plants make to floristic dominance patterns across different regions. Many of the most widespread species are alien plants, and, in particular, Europe and Asia appear as major contributors to the homogenization of the floras in the Americas. We recommend that spatial extent of invasion should be explicitly incorporated in assessments of invasibility, globalization, and risk assessments. ?? 2011 Springer Science+Business Media B.V.

  20. Widespread episodic thiamine deficiency in Northern Hemisphere wildlife

    Science.gov (United States)

    Balk, Lennart; Hägerroth, Per-Åke; Gustavsson, Hanna; Sigg, Lisa; Åkerman, Gun; Ruiz Muñoz, Yolanda; Honeyfield, Dale C.; Tjärnlund, Ulla; Oliveira, Kenneth; Ström, Karin; McCormick, Stephen D.; Karlsson, Simon; Ström, Marika; van Manen, Mathijs; Berg, Anna-Lena; Halldórsson, Halldór P.; Strömquist, Jennie; Collier, Tracy K.; Börjeson, Hans; Mörner, Torsten; Hansson, Tomas

    2016-12-01

    Many wildlife populations are declining at rates higher than can be explained by known threats to biodiversity. Recently, thiamine (vitamin B1) deficiency has emerged as a possible contributing cause. Here, thiamine status was systematically investigated in three animal classes: bivalves, ray-finned fishes, and birds. Thiamine diphosphate is required as a cofactor in at least five life-sustaining enzymes that are required for basic cellular metabolism. Analysis of different phosphorylated forms of thiamine, as well as of activities and amount of holoenzyme and apoenzyme forms of thiamine-dependent enzymes, revealed episodically occurring thiamine deficiency in all three animal classes. These biochemical effects were also linked to secondary effects on growth, condition, liver size, blood chemistry and composition, histopathology, swimming behaviour and endurance, parasite infestation, and reproduction. It is unlikely that the thiamine deficiency is caused by impaired phosphorylation within the cells. Rather, the results point towards insufficient amounts of thiamine in the food. By investigating a large geographic area, by extending the focus from lethal to sublethal thiamine deficiency, and by linking biochemical alterations to secondary effects, we demonstrate that the problem of thiamine deficiency is considerably more widespread and severe than previously reported.

  1. Widespread episodic thiamine deficiency in Northern Hemisphere wildlife

    Science.gov (United States)

    Balk, Lennart; Hägerroth, Per-Åke; Gustavsson, Hanna; Sigg, Lisa; Akerman, Gun; Ruiz Muñoz, Yolanda; Honeyfield, Dale C.; Tjarnlund, Ulla; Oliveira, Kenneth; Strom, Karin; McCormick, Stephen D.; Karlsson, Simon; Strom, Marika; van Manen, Mathijs; Berg, Anna-Lena; Halldórsson, Halldór P.; Stromquist, Jennie; Collier, Tracy K.; Borjeson, Hans; Morner, Torsten; Hansson, Tomas

    2016-01-01

    Many wildlife populations are declining at rates higher than can be explained by known threats to biodiversity. Recently, thiamine (vitamin B1) deficiency has emerged as a possible contributing cause. Here, thiamine status was systematically investigated in three animal classes: bivalves, ray-finned fishes, and birds. Thiamine diphosphate is required as a cofactor in at least five life-sustaining enzymes that are required for basic cellular metabolism. Analysis of different phosphorylated forms of thiamine, as well as of activities and amount of holoenzyme and apoenzyme forms of thiamine-dependent enzymes, revealed episodically occurring thiamine deficiency in all three animal classes. These biochemical effects were also linked to secondary effects on growth, condition, liver size, blood chemistry and composition, histopathology, swimming behaviour and endurance, parasite infestation, and reproduction. It is unlikely that the thiamine deficiency is caused by impaired phosphorylation within the cells. Rather, the results point towards insufficient amounts of thiamine in the food. By investigating a large geographic area, by extending the focus from lethal to sublethal thiamine deficiency, and by linking biochemical alterations to secondary effects, we demonstrate that the problem of thiamine deficiency is considerably more widespread and severe than previously reported.

  2. Research Training, Institutional Support, and Self-Efficacy: Their Impact on Research Activity of Social Workers

    Directory of Open Access Journals (Sweden)

    Mark Thomas Lynch

    2009-11-01

    Full Text Available While the expectations for social work practitioners to do research have increased, their involvement is still limited. We know little about what factors influence involvement in research. The present study proposes a theoretical model that hypothesizes research training and institutional support for research as the exogenous variables, research self-efficacy as an intervening variable, and research activity as the endogenous variable. The study tests the model using data collected from a random sample of social workers. To a large degree the data support the model. Research self-efficacy has a significant effect on research activity. It is also an important mediating variable for the effect of institutional support on research activity. Although institutional support for research has no direct effect, it has an indirect effect via self-efficacy on research activity. However, research training has no effect on research activity and self-efficacy in research. The implications of these findings are discussed.

  3. Reanalyzing Head et al. (2015): investigating the robustness of widespread p-hacking.

    Science.gov (United States)

    Hartgerink, Chris H J

    2017-01-01

    Head et al. (2015) provided a large collection of p -values that, from their perspective, indicates widespread statistical significance seeking (i.e., p -hacking). This paper inspects this result for robustness. Theoretically, the p -value distribution should be a smooth, decreasing function, but the distribution of reported p -values shows systematically more reported p -values for .01, .02, .03, .04, and .05 than p -values reported to three decimal places, due to apparent tendencies to round p -values to two decimal places. Head et al. (2015) correctly argue that an aggregate p -value distribution could show a bump below .05 when left-skew p -hacking occurs frequently. Moreover, the elimination of p  = .045 and p  = .05, as done in the original paper, is debatable. Given that eliminating p  = .045 is a result of the need for symmetric bins and systematically more p -values are reported to two decimal places than to three decimal places, I did not exclude p  = .045 and p  = .05. I conducted Fisher's method .04 hacking remains when we look at the entire range between .04 hacking is widespread. Given the far-reaching implications of supposed widespread p -hacking throughout the sciences Head et al. (2015), it is important that these findings are robust to data analysis choices if the conclusion is to be considered unequivocal. Although no evidence of widespread left-skew p -hacking is found in this reanalysis, this does not mean that there is no p -hacking at all. These results nuance the conclusion by Head et al. (2015), indicating that the results are not robust and that the evidence for widespread left-skew p -hacking is ambiguous at best.

  4. How Work Positions Affect the Research Activity and Information Behaviour of Laboratory Scientists in the Research Lifecycle: Applying Activity Theory

    Science.gov (United States)

    Kwon, Nahyun

    2017-01-01

    Introduction: This study was conducted to investigate the characteristics of research and information activities of laboratory scientists in different work positions throughout a research lifecycle. Activity theory was applied as the conceptual and analytical framework. Method: Taking a qualitative research approach, in-depth interviews and field…

  5. Human Research Program Science Management: Overview of Research and Development Activities

    Science.gov (United States)

    Charles, John B.

    2007-01-01

    An overview of research and development activities of NASA's Human Research Science Management Program is presented. The topics include: 1) Human Research Program Goals; 2) Elements and Projects within HRP; 3) Development and Maintenance of Priorities; 4) Acquisition and Evaluation of Research and Technology Proposals; and 5) Annual Reviews

  6. Infrequent widespread microsatellite instability in hepatocellular carcinomas.

    Science.gov (United States)

    Yamamoto, H; Itoh, F; Fukushima, H; Kaneto, H; Sasaki, S; Ohmura, T; Satoh, T; Karino, Y; Endo, T; Toyota, J; Imai, K

    2000-03-01

    Widespread or high-frequency microsatellite instability (MSI) due to the defective DNA mismatch repair (MMR) occurs in the majority of hereditary non-polyposis colorectal cancer and a subset of sporadic malignant tumors. The incidence of MSI and underlying DNA MMR defects have been well characterized in gastrointestinal carcinogenesis, but not in hepatocarcinogenesis. To address the issue, we analyzed 55 Japanese hepatocellular carcinomas using several indicators of DNA MMR defects, such as microsatellite analysis, loss of heterozygosity (LOH) and mutation analysis of MMR genes, methylation of hMLH1 promoter, and frameshift mutations of mononucleotide repeat sequences within possible target genes. Mutation of beta2-microglobulin gene, which is presumably involved in MSI-positive tumor cell escape from immune surveillance was also examined. Some of these analyses were also carried out in 9 human liver cancer cell lines. None of the 3 quasi-monomorphic mononucleotide markers sensitive for MSI, BAT26, BAT25, and BAT34C4 presented shortened unstable alleles in any of the carcinoma, cirrhosis, chronic hepatitis tissues, or cell lines. LOH at MMR genes was infrequent (4.4 approximately 7.1%), and no mutations were detected. Neither hMLH1 hypermethylation nor frameshift mutation in the target genes was detected. No mutations were found in beta2-microglobulin. Widespread MSI due to the defective DNA MMR appears to play little if any part in Japanese hepatocarcinogenesis.

  7. Research Activities of Geotechnical Research Group of NIIS from the Past to Present

    Science.gov (United States)

    Horii, N.; Toyosawa, Y.; Tamate, S.; Itoh, K.

    In this paper, firstly the memories of Prof. Tatsuoka's laboratory and research works carried out when the first author visited Prof. Tatsuoka's laboratory as a visiting researcher from May 1986 for about 1 year are described. Secondly, the research activities of Geotechnical Research Group of NIIS are introduced. Main emphasis is given on the research activities conducted using old geotechnical centrifuge (NIIS Mark-I centrifuge) and newly developed geotechnical centrifuge (NIIS Mark-II centrifuge).

  8. Fusion research activities in China

    International Nuclear Information System (INIS)

    Deng Xiwen

    1998-01-01

    The fusion program in China has been executed in most areas of magnetic confinement fusion for more than 30 years. Basing on the situation of the power supply requirements of China, the fusion program is becoming an important and vital component of the nuclear power program in China. This paper reviews the status of fusion research and next step plans in China. The motivation and goal of the Chinese fusion program is explained. Research and development on tokamak physics and engineering in the southwestern institute of physics (SWIP) and the institute of plasma physics of Academic Sinica (ASIPP) are introduced. A fusion breeder program and a pure fusion reactor design program have been supported by the state science and technology commission (SSTC) and the China national nuclear corporation (CNNC), respectively. Some features and progress of fusion reactor R and D activities are reviewed. Non fusion applications of plasma science are an important part of China fusion research; a brief introduction about this area is given. Finally, an introductional collaboration network on fusion research activities in China is reported. (orig.)

  9. IMPACT OF BT ( BACILLUS THURINGIENSIS ) CROPS ON BAT ACTIVITY IN SOUTH TEXAS AGROECOSYSTEMS

    Science.gov (United States)

    The widespread adoption of transgenic insecticidal crops raises concerns that nontarget species may be harmed and food webs disrupted. The goal of this research is to determine how transgenic Bt (Bacillus thuringiensis) crops impact the activity of Brazilian freetailed bats (Tada...

  10. A prioritization of research activities

    International Nuclear Information System (INIS)

    Pittman, J.W.

    1988-12-01

    This report presents the results of the efforts in prioritizing the activities in the Office of Research. The purpose of this prioritization is to provide a basis on which to make management decisions. The report describes also the methodology and criteria upon which the priority rankings are based. Each activity was evaluated against four attributes. These attributes are: safety assurance, usefulness, appropriateness and resources. This report will be periodically revised to include the prioritization of new activities, deletion of completed activities and to reflect changes in budget allocations and projections. 3 refs., 5 figs

  11. Brazilian pediatric research groups, lines of research, and main areas of activity

    Directory of Open Access Journals (Sweden)

    Priscila H.A. Oliveira

    2015-06-01

    Full Text Available OBJECTIVES: The Brazilian scientific production in the pediatrics field has been increasing significantly. It is important to identify the distribution and activity of these groups in the country and the main study areas, contributing with data for better resource allocation by institutions. METHODS: An active research was conducted in the National Council of Technological and Scientific Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico [CNPq] website, using as filters the macro area of the research group (Health Sciences, the area (Medicine, and descriptors related to pediatrics. Research lines and main area of pediatric research groups were classified according to the subject predominantly studied by each group. The scientific production of the leader of the pediatric research group between 2011 and 2014 was also analyzed. RESULTS: Most pediatric research groups in Brazil have more than five years of activity and are concentrated in the Southeast and South regions of the country; São Paulo, Rio Grande do Sul, and Minas Gerais are the states with most groups. Of the 132 specific pediatric research groups analyzed, 14.4% have lines of research in multiple areas and 11.4% in child and adolescent health. Among the 585 lines of research of these groups, the most prevalent areas were: oncology, infectious diseases, epidemiology, and gastroenterology. CONCLUSIONS: The pediatric research groups in Brazil have relevant scientific production, including works published in international publications, and are concentrated in regions with higher socioeconomic index. Most groups registered in CNPq started their activity in the last five years (46%, reflecting the recent growth of scientific production in this area.

  12. Fundamental research in developing countries

    International Nuclear Information System (INIS)

    Moravesik, M.J.

    1964-01-01

    Technical assistance is today a widespread activity. Large numbers of persons with special qualifications in the applied sciences go to the developing countries to work on specific research and development projects, as do educationists on Fulbright or other programmes - usually to teach elementary or intermediate courses. But I believe that until now it has been rare for a person primarily interested in fundamental research to go to one of these countries to help build up advanced education and pure research work. Having recently returned from such an assignment, and having found it a most stimulating and enlightening experience, I feel moved to urge strongly upon others who may be in a position to do so that they should seek similar experience themselves. The first step is to show that advanced education and fundamental research are badly needed in the under-developed countries.

  13. Widespread local chronic stressors in Caribbean coastal habitats.

    Science.gov (United States)

    Chollett, Iliana; Collin, Rachel; Bastidas, Carolina; Cróquer, Aldo; Gayle, Peter M H; Jordán-Dahlgren, Eric; Koltes, Karen; Oxenford, Hazel; Rodriguez-Ramirez, Alberto; Weil, Ernesto; Alemu, Jahson; Bone, David; Buchan, Kenneth C; Creary Ford, Marcia; Escalante-Mancera, Edgar; Garzón-Ferreira, Jaime; Guzmán, Hector M; Kjerfve, Björn; Klein, Eduardo; McCoy, Croy; Potts, Arthur C; Ruíz-Rentería, Francisco; Smith, Struan R; Tschirky, John; Cortés, Jorge

    2017-01-01

    Coastal ecosystems and the livelihoods they support are threatened by stressors acting at global and local scales. Here we used the data produced by the Caribbean Coastal Marine Productivity program (CARICOMP), the longest, largest monitoring program in the wider Caribbean, to evidence local-scale (decreases in water quality) and global-scale (increases in temperature) stressors across the basin. Trend analyses showed that visibility decreased at 42% of the stations, indicating that local-scale chronic stressors are widespread. On the other hand, only 18% of the stations showed increases in water temperature that would be expected from global warming, partially reflecting the limits in detecting trends due to inherent natural variability of temperature data. Decreases in visibility were associated with increased human density. However, this link can be decoupled by environmental factors, with conditions that increase the flush of water, dampening the effects of human influence. Besides documenting environmental stressors throughout the basin, our results can be used to inform future monitoring programs, if the desire is to identify stations that provide early warning signals of anthropogenic impacts. All CARICOMP environmental data are now available, providing an invaluable baseline that can be used to strengthen research, conservation, and management of coastal ecosystems in the Caribbean basin.

  14. Assessment report of research and development activities in FY2014. Activity: 'Quantum beam science research' (Result evaluation)

    International Nuclear Information System (INIS)

    2015-09-01

    Japan Atomic Energy Agency (hereafter referred to as 'JAEA') consulted an assessment committee, 'Evaluation Committee of Research Activities for Quantum Beam Science' (hereafter referred to as 'Committee') for result evaluation of 'Quantum Beam Science', in accordance with 'General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research program of the Quantum Beam Science Center (hereafter referred to as 'QuBS') during the period from April 2010 to September 2014. The Committee evaluated the management and research activities of QuBS based on the explanatory documents and oral presentations. (author)

  15. How about integration : the impact of online activities on store satisfaction and loyalty

    NARCIS (Netherlands)

    Teerling, Marije L.

    2004-01-01

    Although there has been widespread support for the concept of integrating the Internet with other channels, relatively little empirical research has been conducted in this area. This paper examines the effects of integrated online activities on customer perceptions, i.e., satisfaction and loyalty,

  16. Radiochemistry teaching and research activities in Brazil

    International Nuclear Information System (INIS)

    Vasconcellos, M.B.A.; Saiki, M.

    2006-01-01

    Much concern has been expressed lately about the decline of teaching and research activities in radiochemistry in many countries, as was discussed in an IAEA Technical Meeting in Antalya, Turkey, in 2002, and also at MTAA-11 in Guildford, UK. In the IAEA meeting, a survey was presented about the current situation in different regions of the world (Eastern Europe, East and West Asia, Africa, North America and Latin America) by experts of each region. In the case of Brazil, which has nuclear research reactors and also cyclotrons in operation, the teaching and research activities in radiochemistry are concentrated in the three main institutes of the Brazilian Nuclear Energy Commission, in the University of Sao Paulo and in other universities, in different regions of the country. In the present paper, a closer look is given to the radiochemistry teaching and research activities that are being conducted nowadays in Brazil, comprising: number of radiochemistry courses and students being formed, main research areas being conducted, as well as research and production of radioisotopes for nuclear medicine, using nuclear reactors and cyclotrons. (author)

  17. The Impact of the Physical Activity Policy Research Network.

    Science.gov (United States)

    Manteiga, Alicia M; Eyler, Amy A; Valko, Cheryl; Brownson, Ross C; Evenson, Kelly R; Schmid, Thomas

    2017-03-01

    Lack of physical activity is one of the greatest challenges of the 21st century. The Physical Activity Policy Research Network (PAPRN) is a thematic network established in 2004 to identify determinants, implementation, and outcomes of policies that are effective in increasing physical activity. The purpose of this study is to describe the products of PAPRN and make recommendations for future research and best practices. A mixed methods approach was used to obtain both quantitative and qualitative data on the network. First, in 2014, PAPRN's dissemination products from 2004 to 2014 were extracted and reviewed, including 57 publications and 56 presentations. Next, semi-structured qualitative interviews were conducted with 25 key network participants from 17 locations around the U.S. The transcripts were transcribed and coded. The results of the interviews indicated that the research network addressed several components of its mission, including the identification of physical activity policies, determinants of these policies, and the process of policy implementation. However, research focusing on physical activity policy outcomes was limited. Best practices included collaboration between researchers and practitioners and involvement of practitioners in research design, data collection, and dissemination of results. PAPRN is an example of a productive research network and has contributed to both the process and content of physical activity policy research over the past decade. Future research should emphasize physical activity policy outcomes. Additionally, increased partnerships with practitioners for collaborative, cross-sectoral physical activity policy research should be developed. Copyright © 2016 American Journal of Preventive Medicine. All rights reserved.

  18. Neutrino Research Group. 2011-2014 activity report

    International Nuclear Information System (INIS)

    2014-01-01

    For the last two decades, neutrino physics has been producing major discoveries including neutrino oscillations. These results gave clear confirmation that active neutrinos oscillate and therefore have mass with three different mass states. This is a very important result showing that the Minimal Standard Model is incomplete and requires an extension which is not yet known. The neutrino research field is very broad and active, at the frontier of today's particle physics. The Neutrino Research Group (GDR) was created in January 2005 with the aim of gathering CEA and CNRS research teams working on Neutrino Physics on experimental or theoretical level. This document is the 2011-2014 activity report of the research group, ten years after its creation. It presents the results of the 5 working groups: 1 - Determination of neutrino parameters; 2 - Physics beyond the standard model; 3 - Neutrinos in the universe; 4 - Accelerators, detection means, R and D and valorisation; 5 - Common tools to all working groups. The research group structure, participating laboratories and teams and the neutrino physics road-map are presented in appendixes

  19. Culturally adapting a physical activity intervention for Somali women: the need for theory and innovation to promote equity.

    Science.gov (United States)

    Murray, Kate E; Ermias, Azieb; Lung, Amber; Mohamed, Amina Sheik; Ellis, B Heidi; Linke, Sarah; Kerr, Jacqueline; Bowen, Deborah J; Marcus, Bess H

    2017-03-01

    There is pressing need for innovation in clinical research to more effectively recruit, engage, retain, and promote health among diverse populations overburdened by health disparities. The purpose of this study is to provide a detailed illustration of the cultural adaptation of an evidence-based intervention to bolster translational research with currently underserved communities. The cultural adaptation heuristic framework described by Barrera and colleagues is applied to the adaptation of a physical activity evidence-based intervention with adult Somali women. Widespread changes were required to ensure program feasibility and acceptability, including the reduction of assessment protocols and changes discordant with current trends in physical activity research. The cultural adaptation of evidence-based interventions offers an important mechanism for reducing health disparities. Improved reporting standards, assessment of features relevant to underserved communities, and greater funding requirements to ensure better representation are needed to promote more widespread access for all people.

  20. A widespread allergic reaction to black tattoo ink caused by laser treatment.

    Science.gov (United States)

    Bernstein, Eric F

    2015-02-01

    This is the first reported case of a local and widespread reaction in a 39 year old woman, to black tattoo ink, induced by Q-switched laser treatment. A 39 year old woman was treated with the Q-switched Nd:YAG laser for removal of a decorative tattoo of her lower back. Subsequent to laser treatment, a severe, widespread allergic reaction developed within and surrounding the treated tattoo. Tattoo reactions subsequent to laser treatment should be considered in addition to reactions to topical antibiotics or wound dressings, following laser treatment of tattoos. © 2015 Wiley Periodicals, Inc.

  1. Assessment report of research and development activities in FY2014. Activity: 'Quantum beam science research' (In-advance evaluation)

    International Nuclear Information System (INIS)

    2015-09-01

    Japan Atomic Energy Agency (hereafter referred to as 'JAEA') consulted an assessment committee, 'Evaluation Committee of Research Activities for Quantum Beam Science' (hereafter referred to as 'Committee') for result evaluation of 'Quantum Beam Science', in accordance with 'General Guideline for the Evaluation of Government Research and Development (R and D) Activities' by Cabinet Office, Government of Japan, 'Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology' and 'Regulation on Conduct for Evaluation of R and D Activities' by JAEA. In response to the JAEA's request, the Committee assessed the research program of the Quantum Beam Science Center (hereafter referred to as 'QuBS') during the period from April 2015 to March 2022. The Committee evaluated the management and research activities of QuBS based on the explanatory documents and oral presentations. (author)

  2. Research engagement of health sciences librarians: a survey of research-related activities and attitudes.

    Science.gov (United States)

    Lessick, Susan; Perryman, Carol; Billman, Brooke L; Alpi, Kristine M; De Groote, Sandra L; Babin, Ted D

    2016-04-01

    The extent to which health sciences librarians are engaged in research is a little-studied question. This study assesses the research activities and attitudes of Medical Library Association (MLA) members, including the influence of work affiliation. An online survey was designed using a combination of multiple-choice and open-ended questions and distributed to MLA members. Responses were analyzed using descriptive statistics, content analysis, and significance testing. The authors used statistical tools and categorized open-ended question topics by the constant comparative method, also applying the broad subject categories used in a prior study. Pearson's chi-square analysis was performed on responses to determine significant differences among respondents employed in three different institutional environments. Analysis showed that 79% of respondents read research articles at least once a month; 58% applied published research studies to practice; 44% had conducted research; 62% reported acting on research had enhanced their libraries; 38% had presented findings; and 34% had authored research articles. Hospital librarians were significantly less likely than academic librarians to have participated in research activities. Highly ranked research benefits, barriers, and competencies of health sciences librarians are described. Findings indicate that health sciences librarians are actively engaged in research activities. Practice implications for practitioners, publishers, and stakeholders are discussed. Results suggest that practitioners can use published research results and results from their own research to affect practice decisions and improve services. Future studies are needed to confirm and extend these findings, including the need for intervention studies to increase research and writing productivity.

  3. Research engagement of health sciences librarians: a survey of research-related activities and attitudes

    Directory of Open Access Journals (Sweden)

    Susan Lessick, MA, MLS, AHIP, FMLA

    2016-11-01

    Full Text Available Introduction: The extent to which health sciences librarians are engaged in research is a little-studied question. This study assesses the research activities and attitudes of Medical Library Association (MLA members, including the influence of work affiliation. Methods: An online survey was designed using a combination of multiple-choice and open-ended questions and distributed to MLA members. Responses were analyzed using descriptive statistics, content analysis, and significance testing. The authors used statistical tools and categorized openended question topics by the constant comparative method, also applying the broad subject categories used in a prior study. Pearson’s chi-square analysis was performed on responses to determine significant differences among respondents employed in three different institutional environments. Results: Analysis showed that 79% of respondents read research articles at least once a month; 58% applied published research studies to practice; 44% had conducted research; 62% reported acting on research had enhanced their libraries; 38% had presented findings; and 34% had authored research articles. Hospital librarians were significantly less likely than academic librarians to have participated in research activities. Highly ranked research benefits, barriers, and competencies of health sciences librarians are described. Conclusions: Findings indicate that health sciences librarians are actively engaged in research activities. Practice implications for practitioners, publishers, and stakeholders are discussed. Results suggest that practitioners can use published research results and results from their own research to affect practice decisions and improve services. Future studies are needed to confirm and extend these findings, including the need for intervention studies to increase research and writing productivity.

  4. Observation-based assessment of functional ability in patients with chronic widespread pain

    DEFF Research Database (Denmark)

    Amris, Kirstine; Wæhrens, Eva Ejlersen; Jespersen, Anders

    2011-01-01

    Knowledge about functional ability, including activities of daily living (ADL), in patients with chronic widespread pain (CWP) and fibromyalgia (FMS) is largely based on self-report. The purpose of this study was to assess functional ability by using standardised, observation-based assessment...... of ADL performance and to examine the relationship between self-reported and observation-based measures of disability. A total of 257 women with CWP, 199 (77%) fulfilling the American College of Rheumatology tender point criteria for FMS, were evaluated with the Assessment of Motor and Process Skills...... (AMPS), an observation-based assessment providing linear measures of ADL motor and ADL process skill ability (unit: logits). A cutoff for effortless and independent ADL task performance is set at 2.0 for the motor scale and 1.0 for the process scale. A total of 248 (96.5%) had ability measures below...

  5. Status of plasma physics research activities in Egypt

    International Nuclear Information System (INIS)

    Masoud, M.M.

    1997-01-01

    The status of plasma physics research activities in Egypt is reviewed. There are nine institutes with plasma research activities. The largest is the Atomic energy Authority (AEA), which has activities in fundamental plasma studies, fusion technology, plasma and laser applications, and plasma simulation. The experiments include Theta Pinches, a Z Pinch, a coaxial discharge, a glow discharge, a CO 2 laser, and the EGYPTOR tokamak. (author)

  6. Subjects with Knee Osteoarthritis Exhibit Widespread Hyperalgesia to Pressure and Cold.

    Directory of Open Access Journals (Sweden)

    Penny Moss

    Full Text Available Hyperalgesia to mechanical and thermal stimuli are characteristics of a range of disorders such as tennis elbow, whiplash and fibromyalgia. This study evaluated the presence of local and widespread mechanical and thermal hyperalgesia in individuals with knee osteoarthritis, compared to healthy control subjects. Twenty-three subjects with knee osteoarthritis and 23 healthy controls, matched for age, gender and body mass index, were recruited for the study. Volunteers with any additional chronic pain conditions were excluded. Pain thresholds to pressure, cold and heat were tested at the knee, ipsilateral heel and ipsilateral elbow, in randomized order, using standardised methodology. Significant between-groups differences for pressure pain and cold pain thresholds were found with osteoarthritic subjects demonstrating significantly increased sensitivity to both pressure (p = .018 and cold (p = .003 stimuli, compared with controls. A similar pattern of results extended to the pain-free ipsilateral ankle and elbow indicating widespread pressure and cold hyperalgesia. No significant differences were found between groups for heat pain threshold, although correlations showed that subjects with greater sensitivity to pressure pain were also likely to be more sensitive to both cold pain and heat pain. This study found widespread elevated pain thresholds in subjects with painful knee osteoarthritis, suggesting that altered nociceptive system processing may play a role in ongoing arthritic pain for some patients.

  7. Research activities of STUK 1995 - 1999

    International Nuclear Information System (INIS)

    Salomaa, S.; Mustonen, R.

    2000-08-01

    The primary goal of STUK, the Finnish Radiation and Nuclear Safety Authority, is to prevent and limit the harmful effects of radiation. The research conducted by STUK yields new information related to the use, occurrence and effects of radiation. The present report summarises STUK's own research activities related to radiation protection in 1995 - 1999. The research and its organisation, scientific strategy and priorities, the impact of results, publications, and the functions of research laboratories are all reviewed. This has been done to provide as background material for an international evaluation of research to be carried out in autumn 2000. (orig.)

  8. Research activities of STUK 1995 - 1999

    Energy Technology Data Exchange (ETDEWEB)

    Salomaa, S.; Mustonen, R. [eds.

    2000-08-01

    The primary goal of STUK, the Finnish Radiation and Nuclear Safety Authority, is to prevent and limit the harmful effects of radiation. The research conducted by STUK yields new information related to the use, occurrence and effects of radiation. The present report summarises STUK's own research activities related to radiation protection in 1995 - 1999. The research and its organisation, scientific strategy and priorities, the impact of results, publications, and the functions of research laboratories are all reviewed. This has been done to provide as background material for an international evaluation of research to be carried out in autumn 2000. (orig.)

  9. Spontaneous and Widespread Electricity Generation in Natural Deep-Sea Hydrothermal Fields.

    Science.gov (United States)

    Yamamoto, Masahiro; Nakamura, Ryuhei; Kasaya, Takafumi; Kumagai, Hidenori; Suzuki, Katsuhiko; Takai, Ken

    2017-05-15

    Deep-sea hydrothermal vents discharge abundant reductive energy into oxidative seawater. Herein, we demonstrated that in situ measurements of redox potentials on the surfaces of active hydrothermal mineral deposits were more negative than the surrounding seawater potential, driving electrical current generation. We also demonstrated that negative potentials in the surface of minerals were widespread in the hydrothermal fields, regardless of the proximity to hydrothermal fluid discharges. Lab experiments verified that the negative potential of the mineral surface was induced by a distant electron transfer from the hydrothermal fluid through the metallic and catalytic properties of minerals. These results indicate that electric current is spontaneously and widely generated in natural mineral deposits in deep-sea hydrothermal fields. Our discovery provides important insights into the microbial communities that are supported by extracellular electron transfer and the prebiotic chemical and metabolic evolution of the ocean hydrothermal systems. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Steps toward validity in active living research: research design that limits accusations of physical determinism.

    Science.gov (United States)

    Riggs, William

    2014-03-01

    "Active living research" has been accused of being overly "physically deterministic" and this article argues that urban planners must continue to evolve research and address biases in this area. The article first provides background on how researchers have dealt with the relationship between the built environment and health over years. This leads to a presentation of how active living research might be described as overly deterministic. The article then offers lessons for researchers planning to embark in active-living studies as to how they might increase validity and minimize criticism of physical determinism. © 2013 Published by Elsevier Ltd.

  11. [Research activity in clinical biochemistry

    DEFF Research Database (Denmark)

    Jorgensen, H.L.; Larsen, B.; Ingwersen, P.

    2008-01-01

    BACKGROUND: Quantitative bibliometric measurements of research activity are frequently used, e.g. for evaluating applicants for academic positions. The purpose of this investigation is to assess research activity within the medical speciality of Clinical Biochemistry by comparing it with a matched...... Clinical Biochemistry, 57 fulfilled the inclusion criteria. Each of these 57 was matched according to medical title with two randomly chosen specialists from other specialities, totaling 114. Using Medline and the Web of Science, the number of publications and the number of citations were then ascertained....... RESULTS: 25% of the 11,691 specialists held a PhD degree or doctoral degree, DMSci, (Clinical Biochemistry: 61%). The 171 specialists included in the study had 9,823 papers in Medline and 10,140 papers in the Web of Science. The number of Medline papers per specialist was 71 for Clinical Biochemistry...

  12. [Research activity in clinical biochemistry

    DEFF Research Database (Denmark)

    Jorgensen, H.L.; Larsen, B.; Ingwersen, P.

    2008-01-01

    Clinical Biochemistry, 57 fulfilled the inclusion criteria. Each of these 57 was matched according to medical title with two randomly chosen specialists from other specialities, totaling 114. Using Medline and the Web of Science, the number of publications and the number of citations were then ascertained......BACKGROUND: Quantitative bibliometric measurements of research activity are frequently used, e.g. for evaluating applicants for academic positions. The purpose of this investigation is to assess research activity within the medical speciality of Clinical Biochemistry by comparing it with a matched....... RESULTS: 25% of the 11,691 specialists held a PhD degree or doctoral degree, DMSci, (Clinical Biochemistry: 61%). The 171 specialists included in the study had 9,823 papers in Medline and 10,140 papers in the Web of Science. The number of Medline papers per specialist was 71 for Clinical Biochemistry...

  13. European commission research activities on iodine

    Energy Technology Data Exchange (ETDEWEB)

    Loggia, E della [European Commission, Brussels (Belgium)

    1996-12-01

    The research on iodine, as on other important fission products which would be released during a severe accident, carried out directly or organized by the European Commission stems from the Euratom Treaty, namely from Chapter III of the treaty which deals with the protection of the health of the population against radiations and from Chapter I which deals with research. In this paper we do not consider the Commission radiological protection programme: we limit ourselves to the presentation of the research carried out on Iodine as part of the most recent source term studies within the framework Programmes as are called the research programme of the European Commission, usually valid for a 4 year periods. The research activities are carried out by the European Commission either directly through the Joint Research Centres (JRC) or indirectly through collaboration with research organizations of Member States. Concerning the iodine research carried out as Direct Action in the Joint Research Centres, are mentioned here the most relevant activities carried out in this field at the JRC of Ispra and Karlsruhe (TUI). As Indirect Action, we present here the results of some studies allocated by the European Commission to experts of research organizations of Member Countries, followed by a short description of the main results achieved by the Reinforced Concerted Action, within the III Framework Programme (1992-1995). At the end of the paper are described the research on iodine being carried out or proposed within the IV Framework Programme (1995-1998). Mention is also done of the Commission participation, relevant in terms of financial and human efforts, to the PHEBUS FP Project. (author) refs.

  14. European commission research activities on iodine

    International Nuclear Information System (INIS)

    Loggia, E. della

    1996-01-01

    The research on iodine, as on other important fission products which would be released during a severe accident, carried out directly or organized by the European Commission stems from the Euratom Treaty, namely from Chapter III of the treaty which deals with the protection of the health of the population against radiations and from Chapter I which deals with research. In this paper we do not consider the Commission radiological protection programme: we limit ourselves to the presentation of the research carried out on Iodine as part of the most recent source term studies within the framework Programmes as are called the research programme of the European Commission, usually valid for a 4 year periods. The research activities are carried out by the European Commission either directly through the Joint Research Centres (JRC) or indirectly through collaboration with research organizations of Member States. Concerning the iodine research carried out as Direct Action in the Joint Research Centres, are mentioned here the most relevant activities carried out in this field at the JRC of Ispra and Karlsruhe (TUI). As Indirect Action, we present here the results of some studies allocated by the European Commission to experts of research organizations of Member Countries, followed by a short description of the main results achieved by the Reinforced Concerted Action, within the III Framework Programme (1992-1995). At the end of the paper are described the research on iodine being carried out or proposed within the IV Framework Programme (1995-1998). Mention is also done of the Commission participation, relevant in terms of financial and human efforts, to the PHEBUS FP Project. (author) refs

  15. Collaboration between physical activity researchers and transport planners

    DEFF Research Database (Denmark)

    Crist, Katie; Bolling, Khalisa; Schipperijn, Jasper

    2018-01-01

    Collaboration between physical activity (PA) researchers and transport planners is a recommended strategy to combat the physical inactivity epidemic. Data collected by PA researchers could be used to identify, implement and evaluate active transport (AT) projects. However, despite aligned interests......, researchers and transport planners rarely collaborate. This study utilized qualitative methods to 1) gain an in-depth understanding of the data utilized in AT planning, 2) explore the utility of Global Positioning Systems (GPS) and accelerometer data in supporting the planning process, 3) identify...... expertise in health or transport planning. A thematic analysis was conducted following structural coding by two researchers. The analysis revealed that geographic and physical activity data that are current, local, objective and specific to individual AT trips would improve upon currently available data...

  16. Climate change and forest fires synergistically drive widespread melt events of the Greenland Ice Sheet.

    Science.gov (United States)

    Keegan, Kaitlin M; Albert, Mary R; McConnell, Joseph R; Baker, Ian

    2014-06-03

    In July 2012, over 97% of the Greenland Ice Sheet experienced surface melt, the first widespread melt during the era of satellite remote sensing. Analysis of six Greenland shallow firn cores from the dry snow region confirms that the most recent prior widespread melt occurred in 1889. A firn core from the center of the ice sheet demonstrated that exceptionally warm temperatures combined with black carbon sediments from Northern Hemisphere forest fires reduced albedo below a critical threshold in the dry snow region, and caused the melting events in both 1889 and 2012. We use these data to project the frequency of widespread melt into the year 2100. Since Arctic temperatures and the frequency of forest fires are both expected to rise with climate change, our results suggest that widespread melt events on the Greenland Ice Sheet may begin to occur almost annually by the end of century. These events are likely to alter the surface mass balance of the ice sheet, leaving the surface susceptible to further melting.

  17. Out of sight, out of mind: why doesn't widespread clinical quality failure command our attention?

    Science.gov (United States)

    Milstein, Arnold; Adler, Nancy E

    2003-01-01

    This paper examines the tolerance by all stakeholders of increasingly well documented evidence of serious and widespread clinical quality failure in the United States. Using research evidence from psychology, it describes specific cognitive and motivational impediments to the perception of quality failure-those shared by all stakeholders and those particularly relevant to patients and their families and to health care professionals. The authors endorse efforts by the National Quality Forum and others to make quality failure more publicly visible. They also point to the pivotal role of health care industry leaders in sustaining focus on a problem that inherently resists visibility.

  18. Widespread Wolbachia infection in terrestrial isopods and other crustaceans

    Directory of Open Access Journals (Sweden)

    Richard Cordaux

    2012-03-01

    Full Text Available Wolbachia bacteria are obligate intracellular alpha-Proteobacteria of arthropods and nematodes. Although widespread among isopod crustaceans, they have seldom been found in non-isopod crustacean species. Here, we report Wolbachia infection in fourteen new crustacean species. Our results extend the range of Wolbachia infections in terrestrial isopods and amphipods (class Malacostraca. We report the occurrence of two different Wolbachia strains in two host species (a terrestrial isopod and an amphipod. Moreover, the discovery of Wolbachia in the goose barnacle Lepas anatifera (subclass Thecostraca establishes Wolbachia infection in class Maxillopoda. The new bacterial strains are closely related to B-supergroup Wolbachia strains previously reported from crustacean hosts. Our results suggest that Wolbachia infection may be much more widespread in crustaceans than previously thought. The presence of related Wolbachia strains in highly divergent crustacean hosts suggests that Wolbachia endosymbionts can naturally adapt to a wide range of crustacean hosts. Given the ability of isopod Wolbachia strains to induce feminization of genetic males or cytoplasmic incompatibility, we speculate that manipulation of crustacean-borne Wolbachia bacteria might represent potential tools for controlling crustacean species of commercial interest and crustacean or insect disease vectors.

  19. Comparative phylogeography of two widespread magpies

    DEFF Research Database (Denmark)

    Zhang, Ruiying; Song, Gang; Qu, Yanhua

    2012-01-01

    Historical geological events and climatic changes are believed to have played important roles in shaping the current distribution of species. However, sympatric species may have responded in different ways to such climatic fluctuations. Here we compared genetic structures of two corvid species......, the Azure-winged Magpie Cyanopica cyanus and the Eurasian Magpie Pica pica, both widespread but with different habitat dependence and some aspects of breeding behavior. Three mitochondrial genes and two nuclear introns were used to examine their co-distributed populations in East China and the Iberian...... Peninsula. Both species showed deep divergences between these two regions that were dated to the late Pliocene/early Pleistocene. In the East Chinese clade of C. cyanus, populations were subdivided between Northeast China and Central China, probably since the early to mid-Pleistocene, and the Central...

  20. Research activities of Sumitomo Electric

    Energy Technology Data Exchange (ETDEWEB)

    1963-07-01

    Research activities of Sumitomo Electric Co. are described and illustrated with numerous photographs. The ehv laboratory is provided with high voltage and heavy current testing facilities such as 1000 kV direct current testing equipment, and a 3000-kV impulse voltage generator.

  1. Integrating research evidence and physical activity policy making

    DEFF Research Database (Denmark)

    Aro, Arja R.; Bertram, Maja; Hämäläinen, Riitta-Maija

    2016-01-01

    Evidence shows that regular physical activity is enhanced by supporting environment. Studies are needed to integrate research evidence into health enhancing, cross-sector physical activity (HEPA) policy making. This article presents the rationale, study design, measurement procedures...... and the initial results of the first phase of six European countries in a five-year research project (2011-2016), REsearch into POlicy to enhance Physical Activity (REPOPA). REPOPA is programmatic research; it consists of linked studies; the first phase studied the use of evidence in 21 policies in implementation...... to learn more in depth from the policy making process and carried out 86 qualitative stakeholder interviews. The second, ongoing phase builds on the central findings of the first phase in each country; it consists of two sets of interventions: game simulations to study cross-sector collaboration...

  2. Activation Theory and Uses and Gratifications Research.

    Science.gov (United States)

    Tate, E. D.

    Uses and gratifications research involves a critical appraisal of conceptual and theoretical issues in mass communication and is concerned with what audience members do with the media. Activation theory understands people as active manipulators of their environment. (Activation refers to that level of psychological and physiological excitement an…

  3. Prevalence of widespread pain and associations with work status: a population study

    Directory of Open Access Journals (Sweden)

    Henriksson KG

    2008-07-01

    Full Text Available Abstract Background This population study based on a representative sample from a Swedish county investigates the prevalence, duration, and determinants of widespread pain (WSP in the population using two constructs and estimates how WSP affects work status. In addition, this study investigates the prevalence of widespread pain and its relationship to pain intensity, gender, age, income, work status, citizenship, civil status, urban residence, and health care seeking. Methods A cross-sectional survey using a postal questionnaire was sent to a representative sample (n = 9952 of the target population (284,073 people, 18–74 years in a county (Östergötland in the southern Sweden. The questionnaire was mailed and followed by two postal reminders when necessary. Results The participation rate was 76.7% (n = 7637; the non-participants were on the average younger, earned less money, and male. Women had higher prevalences of pain in 10 different predetermined anatomical regions. WSP was generally chronic (90–94% and depending on definition of WSP the prevalence varied between 4.8–7.4% in the population. Women had significantly higher prevalence of WSP than men and the age effect appeared to be stronger in women than in men. WSP was a significant negative factor – together with age 50–64 years, low annual income, and non-Nordic citizen – for work status in the community and in the group with chronic pain. Chronic pain but not the spreading of pain was related to health care seeking in the population. Conclusion This study confirms earlier studies that report high prevalences of widespread pain in the population and especially among females and with increasing age. Widespread pain is associated with prominent effects on work status.

  4. Manganese Research Health Project (MHRP)

    Science.gov (United States)

    2009-02-01

    green nucleic acid staining further confirmed the neurotoxic effect of cadmium in this cell model (Fig 10C). Next, we examined the enzymatic activity...Quantification of Nissl bodies revealed a widespread reduction in SNpc cell numbers. Other areas of the basal ganglia were also altered by manganese as...the substantia nigra pars compacta (SNpc) following manganese treatment. Quantification of Nissl bodies revealed a widespread reduction in SNpc

  5. Organization as Information Processing Systems. Toward a Model of the Research Factors Associated with Significant Research Outcomes.

    Science.gov (United States)

    1986-04-01

    institutional conditions enable and reinforce behavior that leads to significant research oit comes. Financial grants, research assistance, and a...include positive instituitional conditions, diverse idea sources and widespread * communications, a goal of theoretical understanding, a relevant research

  6. The origin of widespread species in a poor dispersing lineage (diving beetle genus Deronectes

    Directory of Open Access Journals (Sweden)

    David García-Vázquez

    2016-09-01

    Full Text Available In most lineages, most species have restricted geographic ranges, with only few reaching widespread distributions. How these widespread species reached their current ranges is an intriguing biogeographic and evolutionary question, especially in groups known to be poor dispersers. We reconstructed the biogeographic and temporal origin of the widespread species in a lineage with particularly poor dispersal capabilities, the diving beetle genus Deronectes (Dytiscidae. Most of the ca. 60 described species of Deronectes have narrow ranges in the Mediterranean area, with only four species with widespread European distributions. We sequenced four mitochondrial and two nuclear genes of 297 specimens of 109 different populations covering the entire distribution of the four lineages of Deronectes, including widespread species. Using Bayesian probabilities with an a priori evolutionary rate, we performed (1 a global phylogeny/phylogeography to estimate the relationships of the main lineages within each group and root them, and (2 demographic analyses of the best population coalescent model for each species group, including a reconstruction of the geographical history estimated from the distribution of the sampled localities. We also selected 56 specimens to test for the presence of Wolbachia, a maternally transmitted parasite that can alter the patterns of mtDNA variability. All species of the four studied groups originated in the southern Mediterranean peninsulas and were estimated to be of Pleistocene origin. In three of the four widespread species, the central and northern European populations were nested within those in the northern areas of the Anatolian, Balkan and Iberian peninsulas respectively, suggesting a range expansion at the edge of the southern refugia. In the Mediterranean peninsulas the widespread European species were replaced by vicariant taxa of recent origin. The fourth species (D. moestus was proven to be a composite of unrecognised

  7. Manomaterials research activities at the SPring-8

    International Nuclear Information System (INIS)

    Kimura, Sigeru; Kobayashi, Keisuke

    2005-01-01

    The Ministry of Education, Culture, Sports, Science and Technology, Japan started the 'Nanotechnology Support Project' from 2002 for the purpose to support nanotechnology researches. As part of the nanotechnology support project, SPring-8 has supported nanotechnology researches using synchrotron radiation. In this article, some research activities of the project are introduced. (author)

  8. Federal policies to promote the widespread utilization of photovoltaic systems. Supplement: review and critique

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.L.

    1980-04-15

    This document is intended as a supplement to the two-volume report entitled Federal Policies to Promote the Widespread Utilization of Photovoltaic Systems that was submitted to Congress by the Department of Energy in February and April of 1980. This supplement contains review comments prepared by knowledgeable experts who reviewed early drafts of the Congressional report. Responses to the review comments by the Jet Propulsion Laboratory, preparer of the Congressional report, are also included in this supplement. The Congressional report, mandated in the Solar Photovoltaic Energy Research, Development, and Demonstration Act of 1978 (P.L. 95-590), discusses various issues related to promoting the deployment of photovoltaic systems through the Federal Photovoltaic Program. Various program strategies and funding levels are examined.

  9. Research activities at nuclear research institute in water chemistry and corrosion

    International Nuclear Information System (INIS)

    Kysela, Jan

    2000-01-01

    Research activities at Nuclear Research Institute Rez (NRI) are presented. They are based on former heavy water reactor program and now on pressurized reactors VVER types which are operated on Czech republic. There is LVR-15 research reactor operated in NRI. The reactor and its experimental facilities is utilized for water chemistry and corrosion studies. NRI services for power plants involve water chemistry optimalization, radioactivity build-up, fuel corrosion and structural materials corrosion tests. (author)

  10. Crossing the Telemedicine Chasm: Have the U.S. Barriers to Widespread Adoption of Telemedicine Been Significantly Reduced?

    Directory of Open Access Journals (Sweden)

    Cynthia LeRouge

    2013-11-01

    Full Text Available Barriers have challenged widespread telemedicine adoption by health care organizations for 40 years. These barriers have been technological, financial, and legal and have also involved business strategy and human resources. The article canvasses recent trends—events and activities in each of these areas as well as US health reform activities that might help to break down these barriers. The key to telemedicine success in the future is to view it as an integral part of health care services and not as a stand-alone project. Telemedicine must move from experimental and separate to integrated and equivalent to other health services within health care organizations. Furthermore, telemedicine serves as vital connective tissue for expanding health care organization networks.

  11. Basic Neuroscience Research with Nonhuman Primates: A Small but Indispensable Component of Biomedical Research

    NARCIS (Netherlands)

    Roelfsema, P.R.; Treue, S.

    2014-01-01

    Research with nonhuman primates represents a small component of neuroscience with far-reaching relevance that is irreplaceable for essential insights into cognitive functions, brain disease, and therapy. Transparency and widespread information about this research and its importance is central to

  12. Basic neuroscience research with nonhuman primates: a small but indispensable component of biomedical research

    NARCIS (Netherlands)

    Roelfsema, Pieter R.; Treue, Stefan

    2014-01-01

    Research with nonhuman primates represents a small component of neuroscience with far-reaching relevance that is irreplaceable for essential insights into cognitive functions, brain disease, and therapy. Transparency and widespread information about this research and its importance is central to

  13. Basic neuroscience research with nonhuman primates : a small but indispensable component of biomedical research

    NARCIS (Netherlands)

    Roelfsema, Pieter R; Treue, Stefan

    2014-01-01

    Research with nonhuman primates represents a small component of neuroscience with far-reaching relevance that is irreplaceable for essential insights into cognitive functions, brain disease, and therapy. Transparency and widespread information about this research and its importance is central to

  14. Research Note: Comparative antibacterial activities of oil-palm ...

    African Journals Online (AJOL)

    Research Note: Comparative antibacterial activities of oil-palm Elaeis ... The antimicrobial activities liquid pyrolysates (obtained by destructive distillation), their ... respective chloroform fractions which showed higher activities than the crude ...

  15. Applied superconductivity and cryogenic research activities in NIFS

    International Nuclear Information System (INIS)

    Mito, T.; Sagara, A.; Imagawa, S.; Yamada, S.; Takahata, K.; Yanagi, N.; Chikaraishi, H.; Maekawa, R.; Iwamoto, A.; Hamaguchi, S.; Sato, M.; Noda, N.; Yamauchi, K.; Komori, A.; Motojima, O.

    2006-01-01

    Since the foundation of National Institute for Fusion Science (NIFS) in 1989, the primary mission of the applied superconductivity and cryogenic researches has been focused on the development of the large helical device (LHD): the largest fusion experimental apparatus exclusively utilizing superconducting technologies. The applied superconductivity and cryogenics group in NIFS was organized to be responsible for this activity. As a result of extensive research activities, the construction of LHD was completed in 1997. Since then, the LHD superconducting system has been demonstrating high availability of more than 97% during eight years operation and it keeps proving high reliability of large-scale superconducting systems. This paper describes the extensive activities of the applied superconductivity and cryogenic researches in NIFS during and after the development of LHD and the fundamental researches that aim at realizing a helical-type fusion reactor

  16. Instructor-Created Activities to Engage Undergraduate Nursing Research Students.

    Science.gov (United States)

    Pierce, Linda L; Reuille, Kristina M

    2018-03-01

    In flipped or blended classrooms, instruction intentionally shifts to a student-centered model for a problem-based learning approach, where class time explores topics in greater depth, creating meaningful learning opportunities. This article describes instructor-created activities focused on research processes linked to evidence-based practice that engage undergraduate nursing research students. In the classroom, these activities include individual and team work to foster critical thinking and stimulate student discussion of topic material. Six activities for small and large student groups are related to quantitative, qualitative, and both research processes, as well as applying research evidence to practice. Positive student outcomes included quantitative success on assignments and robust student topic discussions, along with instructor-noted overall group engagement and interest. Using these activities can result in class time for the construction of meaning, rather than primarily information transmission. Instructors may adopt these activities to involve and stimulate students' critical thinking about research and evidence-based practice. [J Nurs Educ. 2018;57(3):174-177.]. Copyright 2018, SLACK Incorporated.

  17. Reanalyzing Head et al. (2015: investigating the robustness of widespread p-hacking

    Directory of Open Access Journals (Sweden)

    Chris H.J. Hartgerink

    2017-03-01

    Full Text Available Head et al. (2015 provided a large collection of p-values that, from their perspective, indicates widespread statistical significance seeking (i.e., p-hacking. This paper inspects this result for robustness. Theoretically, the p-value distribution should be a smooth, decreasing function, but the distribution of reported p-values shows systematically more reported p-values for .01, .02, .03, .04, and .05 than p-values reported to three decimal places, due to apparent tendencies to round p-values to two decimal places. Head et al. (2015 correctly argue that an aggregate p-value distribution could show a bump below .05 when left-skew p-hacking occurs frequently. Moreover, the elimination of p = .045 and p = .05, as done in the original paper, is debatable. Given that eliminating p = .045 is a result of the need for symmetric bins and systematically more p-values are reported to two decimal places than to three decimal places, I did not exclude p = .045 and p = .05. I conducted Fisher’s method .04 < p < .05 and reanalyzed the data by adjusting the bin selection to .03875 < p ≤ .04 versus .04875 < p ≤ .05. Results of the reanalysis indicate that no evidence for left-skew p-hacking remains when we look at the entire range between .04 < p < .05 or when we inspect the second-decimal. Taking into account reporting tendencies when selecting the bins to compare is especially important because this dataset does not allow for the recalculation of the p-values. Moreover, inspecting the bins that include two-decimal reported p-values potentially increases sensitivity if strategic rounding down of p-values as a form of p-hacking is widespread. Given the far-reaching implications of supposed widespread p-hacking throughout the sciences Head et al. (2015, it is important that these findings are robust to data analysis choices if the conclusion is to be considered unequivocal. Although no evidence of widespread left-skew p

  18. A new taxonomy for stakeholder engagement in patient-centered outcomes research.

    Science.gov (United States)

    Concannon, Thomas W; Meissner, Paul; Grunbaum, Jo Anne; McElwee, Newell; Guise, Jeanne-Marie; Santa, John; Conway, Patrick H; Daudelin, Denise; Morrato, Elaine H; Leslie, Laurel K

    2012-08-01

    Despite widespread agreement that stakeholder engagement is needed in patient-centered outcomes research (PCOR), no taxonomy exists to guide researchers and policy makers on how to address this need. We followed an iterative process, including several stages of stakeholder review, to address three questions: (1) Who are the stakeholders in PCOR? (2) What roles and responsibilities can stakeholders have in PCOR? (3) How can researchers start engaging stakeholders? We introduce a flexible taxonomy called the 7Ps of Stakeholder Engagement and Six Stages of Research for identifying stakeholders and developing engagement strategies across the full spectrum of research activities. The path toward engagement will not be uniform across every research program, but this taxonomy offers a common starting point and a flexible approach.

  19. Coordinated research activities: Annual report and statistics for 2004

    International Nuclear Information System (INIS)

    2005-05-01

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The Agency's Coordinated Research Activities stimulate and coordinate the undertaking of research in selected nuclear fields by scientists in IAEA Member States. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These Coordinated Research Activities are normally implemented through Coordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual research contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports Doctoral CRPs, which are designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs currently implemented by the Human Health programme address the management of liver cancer using radionuclide methods, improvement of radiotherapy outcomes in AIDS cancer patients and isotopic and complementary tools for the study of micronutrient status and interactions in developing country populations exposed to multiple nutritional deficiencies. Further information on the Agency's coordinated research activities

  20. Coordinated research activities: Annual report and statistics for 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-05-15

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The Agency's Coordinated Research Activities stimulate and coordinate the undertaking of research in selected nuclear fields by scientists in IAEA Member States. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These Coordinated Research Activities are normally implemented through Coordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual research contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports Doctoral CRPs, which are designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs currently implemented by the Human Health programme address the management of liver cancer using radionuclide methods, improvement of radiotherapy outcomes in AIDS cancer patients and isotopic and complementary tools for the study of micronutrient status and interactions in developing country populations exposed to multiple nutritional deficiencies. Further information on the Agency's coordinated research activities

  1. Crossing the Telemedicine Chasm: Have the U.S. Barriers to Widespread Adoption of Telemedicine Been Significantly Reduced? †

    Science.gov (United States)

    LeRouge, Cynthia; Garfield, Monica J.

    2013-01-01

    Barriers have challenged widespread telemedicine adoption by health care organizations for 40 years. These barriers have been technological, financial, and legal and have also involved business strategy and human resources. The article canvasses recent trends—events and activities in each of these areas as well as US health reform activities that might help to break down these barriers. The key to telemedicine success in the future is to view it as an integral part of health care services and not as a stand-alone project. Telemedicine must move from experimental and separate to integrated and equivalent to other health services within health care organizations. Furthermore, telemedicine serves as vital connective tissue for expanding health care organization networks. PMID:24287864

  2. The relative frequencies of causes of widespread ground-glass opacity: A retrospective cohort

    International Nuclear Information System (INIS)

    Hewitt, Michael G.; Miller, Wallace T.; Reilly, Thomas J.; Simpson, Scott

    2014-01-01

    Highlights: • The most common cause of widespread ground-glass opacities is hydrostatic pulmonary edema. • Associated findings such as air-trapping and centrilobular nodules are highly specific for hypersensitivity pneumonitis. • The clinical setting (outpatient versus inpatient) will alter the order of the differential diagnosis. - Abstract: Purpose: The purpose of our study was to determine the relative frequencies of causes of widespread ground-glass opacity (GGO) in an unselected, consecutive patient population and to identify any associated imaging findings that can narrow or reorganize the differential. Materials and methods: The study was approved by the center's IRB and is HIPPA compliant. Cases with widespread GGO in the radiology report were identified by searching the Radiology Information System. Medical records and CT scan examinations were reviewed for the causes of widespread GGO. Associations between a less dominant imaging finding and a particular diagnosis were analyzed with the chi square test. Our study group consisted of 234 examinations with 124 women and 110 men and a mean age of 53.7 years. Results: A cause was established in 204 (87.2%) cases. Hydrostatic pulmonary edema was most common with 131 cases (56%). Interstitial lung diseases (ILD) were the next most common, most often hypersensitivity pneumonitis (HP) (n = 12, 5%) and connective tissue disease related ILD (n = 7, 3%). Infection accounted for 5% (12 cases). A few miscellaneous diseases accounted for 5 cases (2.1%). The combination of septal thickening and pleural effusions had a specificity of 0.91 for hydrostatic pulmonary edema (P < .001) while centrilobular nodules and air trapping had a specificity of 1.0 for HP. In 24 (10.2%) patients, increased opacification from expiration was incorrectly interpreted as representing widespread ground glass opacity. The relative frequency of disease dramatically changed according to the setting. In the inpatient setting, diffuse

  3. The relative frequencies of causes of widespread ground-glass opacity: A retrospective cohort

    Energy Technology Data Exchange (ETDEWEB)

    Hewitt, Michael G., E-mail: Mike_hewitt@me.com; Miller, Wallace T., E-mail: Wallace.miller@uphs.upenn.edu; Reilly, Thomas J., E-mail: thomasjreilly@comcast.net; Simpson, Scott, E-mail: Simpson80@gmail.com

    2014-10-15

    Highlights: • The most common cause of widespread ground-glass opacities is hydrostatic pulmonary edema. • Associated findings such as air-trapping and centrilobular nodules are highly specific for hypersensitivity pneumonitis. • The clinical setting (outpatient versus inpatient) will alter the order of the differential diagnosis. - Abstract: Purpose: The purpose of our study was to determine the relative frequencies of causes of widespread ground-glass opacity (GGO) in an unselected, consecutive patient population and to identify any associated imaging findings that can narrow or reorganize the differential. Materials and methods: The study was approved by the center's IRB and is HIPPA compliant. Cases with widespread GGO in the radiology report were identified by searching the Radiology Information System. Medical records and CT scan examinations were reviewed for the causes of widespread GGO. Associations between a less dominant imaging finding and a particular diagnosis were analyzed with the chi square test. Our study group consisted of 234 examinations with 124 women and 110 men and a mean age of 53.7 years. Results: A cause was established in 204 (87.2%) cases. Hydrostatic pulmonary edema was most common with 131 cases (56%). Interstitial lung diseases (ILD) were the next most common, most often hypersensitivity pneumonitis (HP) (n = 12, 5%) and connective tissue disease related ILD (n = 7, 3%). Infection accounted for 5% (12 cases). A few miscellaneous diseases accounted for 5 cases (2.1%). The combination of septal thickening and pleural effusions had a specificity of 0.91 for hydrostatic pulmonary edema (P < .001) while centrilobular nodules and air trapping had a specificity of 1.0 for HP. In 24 (10.2%) patients, increased opacification from expiration was incorrectly interpreted as representing widespread ground glass opacity. The relative frequency of disease dramatically changed according to the setting. In the inpatient setting, diffuse

  4. IAEA activities in the field of research reactors safety

    International Nuclear Information System (INIS)

    Ciuculescu, C.; Boado Magan, H.J.

    2004-01-01

    IAEA activities in the field of research reactor safety are included in the programme of the Division of Nuclear Installations Safety. Following the objectives of the Division, the results of the IAEA missions and the recommendations from International Advisory Groups, the IAEA has conducted in recent years a certain number of activities aiming to enhance the safety of research reactors. The following activities will be presented: (a) the new Requirements for the Safety of Research Reactors, main features and differences with previous standards (SS-35-S1 and SS-35-S2) and the grading approach for implementation; (b) new documents being developed (safety guides, safety reports and TECDOC's); (c) activities related to the Incident Reporting System for Research Reactor (IRSRR); (d) the new features implemented for the INSARR missions; (e) the Code of Conduct on the Safety of Research Reactors adopted by the Board of Governors on 8 March 2004, following the General Conference Resolution GC(45)/RES/10; and (f) the survey on the safety of research reactors published on the IAEA website on February 2003 and the results obtained. (author)

  5. International arrivals: widespread bioinvasions in European Seas.

    Science.gov (United States)

    Galil, B S; Marchini, A; Occhipinti-Ambrogi, A; Minchin, D; Narščius, A; Ojaveer, H; Olenin, S

    2014-04-01

    The European Union lacks a comprehensive framework to address the threats posed by the introduction and spread of marine non-indigenous species (NIS). Current efforts are fragmented and suffer substantial gaps in coverage. In this paper we identify and discuss issues relating to the assessment of spatial and temporal patterns of introductions in European Seas (ES), based on a scientifically validated information system of aquatic non-indigenous and cryptogenic species, AquaNIS. While recognizing the limitations of the existing data, we extract information that can be used to assess the relative risk of introductions for different taxonomic groups, geographic regions and likely vectors. The dataset comprises 879 multicellular NIS. We applied a country-based approach to assess patterns of NIS richness in ES, and identify the principal introduction routes and vectors, the most widespread NIS and their spatial and temporal spread patterns. Between 1970 and 2013, the number of recorded NIS has grown by 86, 173 and 204% in the Baltic, Western European margin and the Mediterranean, respectively; 52 of the 879 NIS were recorded in 10 or more countries, and 25 NIS first recorded in European seas since 1990 have since been reported in five or more countries. Our results highlight the ever-rising role of shipping (commercial and recreational) as a vector for the widespread and recently spread NIS. The Suez Canal, a corridor unique to the Mediterranean, is responsible for the increased introduction of new thermophilic NIS into this warming sea. The 2020 goal of the EU Biodiversity Strategy concerning marine Invasive Alien Species may not be fully attainable. The setting of a new target date should be accompanied by scientifically robust, sensible and pragmatic plans to minimize introductions of marine NIS and to study those present.

  6. How consumer physical activity monitors could transform human physiology research

    Science.gov (United States)

    Hall Brown, Tyish S.; Collier, Scott R.; Sandberg, Kathryn

    2017-01-01

    A sedentary lifestyle and lack of physical activity are well-established risk factors for chronic disease and adverse health outcomes. Thus, there is enormous interest in measuring physical activity in biomedical research. Many consumer physical activity monitors, including Basis Health Tracker, BodyMedia Fit, DirectLife, Fitbit Flex, Fitbit One, Fitbit Zip, Garmin Vivofit, Jawbone UP, MisFit Shine, Nike FuelBand, Polar Loop, Withings Pulse O2, and others have accuracies similar to that of research-grade physical activity monitors for measuring steps. This review focuses on the unprecedented opportunities that consumer physical activity monitors offer for human physiology and pathophysiology research because of their ability to measure activity continuously under real-life conditions and because they are already widely used by consumers. We examine current and potential uses of consumer physical activity monitors as a measuring or monitoring device, or as an intervention in strategies to change behavior and predict health outcomes. The accuracy, reliability, reproducibility, and validity of consumer physical activity monitors are reviewed, as are limitations and challenges associated with using these devices in research. Other topics covered include how smartphone apps and platforms, such as the Apple ResearchKit, can be used in conjunction with consumer physical activity monitors for research. Lastly, the future of consumer physical activity monitors and related technology is considered: pattern recognition, integration of sleep monitors, and other biosensors in combination with new forms of information processing. PMID:28052867

  7. How consumer physical activity monitors could transform human physiology research.

    Science.gov (United States)

    Wright, Stephen P; Hall Brown, Tyish S; Collier, Scott R; Sandberg, Kathryn

    2017-03-01

    A sedentary lifestyle and lack of physical activity are well-established risk factors for chronic disease and adverse health outcomes. Thus, there is enormous interest in measuring physical activity in biomedical research. Many consumer physical activity monitors, including Basis Health Tracker, BodyMedia Fit, DirectLife, Fitbit Flex, Fitbit One, Fitbit Zip, Garmin Vivofit, Jawbone UP, MisFit Shine, Nike FuelBand, Polar Loop, Withings Pulse O 2 , and others have accuracies similar to that of research-grade physical activity monitors for measuring steps. This review focuses on the unprecedented opportunities that consumer physical activity monitors offer for human physiology and pathophysiology research because of their ability to measure activity continuously under real-life conditions and because they are already widely used by consumers. We examine current and potential uses of consumer physical activity monitors as a measuring or monitoring device, or as an intervention in strategies to change behavior and predict health outcomes. The accuracy, reliability, reproducibility, and validity of consumer physical activity monitors are reviewed, as are limitations and challenges associated with using these devices in research. Other topics covered include how smartphone apps and platforms, such as the Apple ResearchKit, can be used in conjunction with consumer physical activity monitors for research. Lastly, the future of consumer physical activity monitors and related technology is considered: pattern recognition, integration of sleep monitors, and other biosensors in combination with new forms of information processing. Copyright © 2017 the American Physiological Society.

  8. Electromechanically active polymer transducers: research in Europe

    DEFF Research Database (Denmark)

    Carpi, Federico; Graz, Ingrid; Jager, Edwin

    2013-01-01

    Smart materials and structures based on electromechanically active polymers (EAPs) represent a fast growing and stimulating field of research and development. EAPs are materials capable of changing dimensions and/or shape in response to suitable electrical stimuli. They are commonly classified...... usages from the micro- to the macro-scale, spanning several disciplines, such as mechatronics, robotics, automation, biotechnology and biomedical engineering, haptics, fluidics, optics and acoustics. Currently, the EAP field is just undergoing its initial transition from academic research...... worldwide. The rapid expansion of the EAP field in Europe, where it historically has strong roots, has stimulated the creation of the 'European Scientific Network for Artificial Muscles—ESNAM', entirely focused on EAPs and gathering the most active research institutes, as well as key industrial developers...

  9. Danish integrated antimicrobial in resistance monitoring and research program

    DEFF Research Database (Denmark)

    Hammerum, Anette Marie; Heuer, Ole Eske; Emborg, Hanne-Dorthe

    2007-01-01

    a systematic and continuous monitoring program of antimicrobial drug consumption and antimicrobial agent resistance in animals, food, and humans, the Danish Integrated Antimicrobial Resistance Monitoring and Research Program (DANMAP). Monitoring of antimicrobial drug resistance and a range of research......Resistance to antimicrobial agents is an emerging problem worldwide. Awareness of the undesirable consequences of its widespread occurrence has led to the initiation of antimicrobial agent resistance monitoring programs in several countries. In 1995, Denmark was the first country to establish...... activities related to DANMAP have contributed to restrictions or bans of use of several antimicrobial agents in food animals in Denmark and other European Union countries....

  10. Top 10 research questions related to children physical activity motivation.

    Science.gov (United States)

    Chen, Ang

    2013-12-01

    Physical activity is critical to healthy development of children. It is well documented that helping children develop and sustain a physically active lifestyle requires children to become motivated. Many studies have been conducted in the past 2.5 decades on determinants and correlates for children and adolescents' physical activity motivation. The findings have informed researchers and practitioners about motivation sources for children and effective strategies to motivate children in given physical activity settings. Built on the extensive knowledge base and theoretical platforms formed by these research studies, the purpose of this article is to take a look at the current research landscape and provide subjective thoughts about what we still need to know about children's physical activity motivation. The product of this subjective thinking process rendered 10 potential questions for future research on children's physical activity motivation in both in-school and out-of-school settings. These topics encompass those focusing on children's physical activity motivation as a mental dispositional process, those conceptualizing the motivation as an outcome of person-environment interactions, and those attempting to dissect the motivation as an outcome of social-cultural influences and educational policies. It is hoped that the topics can serve researchers interested in children's physical activity motivation as starting blocks from which they can extend their conceptual thinking and identify research questions that are personally meaningful. It is also hoped that the list of potential questions can be helpful to researchers in accomplishing the imperative and significant mission to motivate children to be physically active in the 21st century and beyond.

  11. Coordinated research activities: Annual report and statistics for 2005

    International Nuclear Information System (INIS)

    2006-06-01

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The Agency's Coordinated Research Activities stimulate and coordinate the undertaking of research in selected nuclear fields by scientists in IAEA Member States. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These Coordinated Research Activities are normally implemented through Coordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual research contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports Doctoral CRPs, which are designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs currently implemented by the Human Health programme address the management of liver cancer using radionuclide methods, improvement of radiotherapy outcomes in AIDS cancer patients and isotopic and complementary tools for the study of micronutrient status and interactions in developing country populations exposed to multiple nutritional deficiencies. Further information on the Agency's Coordinated Research Activities contained

  12. Coordinated research activities: Annual report and statistics for 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-06-15

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The Agency's Coordinated Research Activities stimulate and coordinate the undertaking of research in selected nuclear fields by scientists in IAEA Member States. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These Coordinated Research Activities are normally implemented through Coordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual research contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports Doctoral CRPs, which are designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs currently implemented by the Human Health programme address the management of liver cancer using radionuclide methods, improvement of radiotherapy outcomes in AIDS cancer patients and isotopic and complementary tools for the study of micronutrient status and interactions in developing country populations exposed to multiple nutritional deficiencies. Further information on the Agency's Coordinated Research Activities contained

  13. Added value of second biopsy target in screen-detected widespread suspicious breast calcifications.

    Science.gov (United States)

    Falkner, Nathalie M; Hince, Dana; Porter, Gareth; Dessauvagie, Ben; Jeganathan, Sanjay; Bulsara, Max; Lo, Glen

    2018-06-01

    There is controversy on the optimal work-up of screen-detected widespread breast calcifications: whether to biopsy a single target or multiple targets. This study evaluates agreement between multiple biopsy targets within the same screen-detected widespread (≥25 mm) breast calcification to determine if the second biopsy adds value. Retrospective observational study of women screened in a statewide general population risk breast cancer mammographic screening program from 2009 to 2016. Screening episodes recalled for widespread calcifications where further views indicated biopsy, and two or more separate target areas were sampled within the same lesion were included. Percentage agreement and Cohen's Kappa were calculated. A total of 293317 women were screened during 761124 separate episodes with recalls for widespread calcifications in 2355 episodes. In 171 women, a second target was biopsied within the same lesion. In 149 (86%) cases, the second target biopsy result agreed with the first biopsy (κ = 0.6768). Agreement increased with increasing mammography score (85%, 86% and 92% for score 3, 4 and 5 lesions). Same day multiple biopsied lesions were three times more likely to yield concordant results compared to post-hoc second target biopsy cases. While a single target biopsy is sufficient to discriminate a benign vs. malignant diagnosis in most cases, in 14% there is added value in performing a second target biopsy. Biopsies performed prospectively are more likely to yield concordant results compared to post-hoc second target biopsy cases, suggesting a single prospective biopsy may be sufficient when results are radiological-pathological concordant; discordance still requires repeat sampling. © 2018 The Royal Australian and New Zealand College of Radiologists.

  14. DataShare: Empowering Researcher Data Curation

    Directory of Open Access Journals (Sweden)

    Stephen Abrams

    2014-07-01

    Full Text Available Researchers are increasingly being asked to ensure that all products of research activity – not just traditional publications – are preserved and made widely available for study and reuse as a precondition for publication or grant funding, or to conform to disciplinary best practices. In order to conform to these requirements, scholars need effective, easy-to-use tools and services for the long-term curation of their research data. The DataShare service, developed at the University of California, is being used by researchers to: (1 prepare for curation by reviewing best practice recommendations for the acquisition or creation of digital research data; (2 select datasets using intuitive file browsing and drag-and-drop interfaces; (3 describe their data for enhanced discoverability in terms of the DataCite metadata schema; (4 preserve their data by uploading to a public access collection in the UC3 Merritt curation repository; (5 cite their data in terms of persistent and globally-resolvable DOI identifiers; (6 expose their data through registration with well-known abstracting and indexing services and major internet search engines; (7 control the dissemination of their data through enforceable data use agreements; and (8 discover and retrieve datasets of interest through a faceted search and browse environment. Since the widespread adoption of effective data management practices is highly dependent on ease of use and integration into existing individual, institutional, and disciplinary workflows, the emphasis throughout the design and implementation of DataShare is to provide the highest level of curation service with the lowest possible technical barriers to entry by individual researchers. By enabling intuitive, self-service access to data curation functions, DataShare helps to contribute to more widespread adoption of good data curation practices that are critical to open scientific inquiry, discourse, and advancement.

  15. Reanalyzing Head et al. : Investigating the robustness of widespread p-hacking

    NARCIS (Netherlands)

    Hartgerink, C.H.J.

    2017-01-01

    Head et al. (2015) provided a large collection of p-values that, from their perspective, indicates widespread statistical significance seeking (i.e., p-hacking). This paper inspects this result for robustness. Theoretically, the p-value distribution should be a smooth, decreasing function, but the

  16. Encouraging entrepreneurship in university labs: Research activities, research outputs, and early doctorate careers

    OpenAIRE

    Roach, Michael

    2017-01-01

    This paper investigates how the encouragement of entrepreneurship within university research labs relates with research activities, research outputs, and early doctorate careers. Utilizing a panel survey of 6,840 science & engineering doctoral students at 39 R1 research universities, this study shows that entrepreneurship is widely encouraged across university research labs, ranging from 54% in biomedical engineering to 18% in particle physics, while only a small share of labs openly discoura...

  17. Widespread microbiological groundwater contamination in the South-eastern Salento (Puglia-Italy).

    Science.gov (United States)

    Lugoli, F; Leopizzi, M I; Bagordo, F; Grassi, T; Guido, M; De Donno, A

    2011-01-01

    In the Salento peninsula (Puglia Region, South-East Italy), underground waters are a fundamental resource for the population because they constitute the principal reservoir for drinking water and irrigation. They are, however, affected by overexploitation. The risk factors in the Salento arise mainly from anthropic activities, especially tourism and agriculture (leaking wells, sewage and inadequate waste disposal procedures). The Southern Salento is recognized to be at high risk of pathologies characterised by oral-faecal transmission. From 2001 to 2009 the incidence of typhoid fever in the Salento was 12.11/100,000 inhabitants as against 2.91 in Italy. Enteritis caused by rotaviruses is an important cause of hospitalization of paediatric-aged children in the Salento, with high social costs. An effective monitoring system for the conservation and management of water bodies and the protection of public health is therefore fundamental. The present study sought to determine the microbiological and chemical-physical quality of groundwater in the Salento and to analyse the factors associated with contamination. The results indicated widespread pollution from salt and microbial contamination. Contamination from faecal microorganisms posed a significant risk of human infection in 100% of samples. Furthermore, the water was unsuitable even for irrigation in a high percentage of cases (31.8%), which is of considerable significance given that agriculture is one of the most important economic activities in the area under study. The high salt concentration was probably due to excessive extraction of water for intensive irrigation, especially in summer. Under these circumstances, some of mitigation activity is necessary. Furthermore, it would be advisable to decrease the pollution load from anthropic activities in the territory and to reduce water consumption in order to conserve groundwater resources especially.

  18. Prevalence and risk factors of vitamin D deficiency in patients with widespread musculoskeletal pain

    Directory of Open Access Journals (Sweden)

    Muharrem Çidem

    2013-12-01

    Full Text Available Objective: Vitamin D deficiency is a worldwide common health problems. Vitamin D deficiency in adults has been associated with proximal muscle weakness, skeletal mineralization defect, and an increased risk of falling. Patients with vitamin D deficiency commonly complain of widespread pain in the body. The aim of this study was to examine the prevalence and risk factors of 25-hydroxyvitamin D deficiency in patients complaining of widespread musculoskeletal pain. Methods: In this cross-sectional study, 8457 patients with widespread musculoskeletal pain (7772 females, 685 males, aged 46.7 (range 20-100 years were included. Serum 25-hydroxyvitamin D was measured with ELISA method. Patients were classified into two groups: 1 Patients with vitamin D deficiency (20 ng/ml. Results: Prevalence of vitamin D deficiency was found to be 71.7%. A binary logistic regression model showed that low 25(OHVit D level was associated with gender, age and month in which 25(OH hypovitaminosis was determined. The risk of low 25(OH Vit D was found to be 2.15 times higher in female patients and 1.52 times higher on March and 1.55 times higher on April. Conclusion: This study indicates that Vitamin D deficiency should be taken into consideration in patients with widespread musculoskeletal pain, and some precautions such as sunbathe during summer should be recommended patients having risk of vitamin D deficiency. J Clin Exp Invest 2013; 4 (4: 48-491

  19. To Support Research Activities Under the NASA Experimental Program to Stimulate Competitive Research

    Science.gov (United States)

    Gregory, John C.

    2003-01-01

    The Alabama NASA EPSCoR Program is a collaborative venture of The Alabama Space Grant Consortium, The Alabama EPSCoR, and faculty and staff at 10 Alabama colleges and universities as well as the Alabama School of Math and Science in Mobile. There are two Research Clusters which include infrastructure-building and outreach elements embedded in their research activities. Each of the two Research Clusters is in an area of clear and demonstrable relevance to NASA's mission, to components of other Alabama EPSCoR projects, and to the State of Alabama's economic development. This Final Report summarizes and reports upon those additional activities occurring after the first report was submitted in March 2000 (included here as Appendix C). Since the nature of the activities and the manner in which they relate to one another differ by cluster, these clusters function independently and are summarized in parallel in this report. They do share a common administration by the Alabama Space Grant Consortium (ASGC) and by this means, good ideas from each group were communicated to the other, as appropriate. During the past year these research teams, involving 15 scientists, 16 graduate students, 16 undergraduates, and 7 high school students involving 10 Alabama universities had 14 peer reviewed scientific journal articles published, 21 others reviewed for publication or published in proceedings, gave 7 formal presentations and numerous informal presentations to well over 3000 people, received 3 patents and were awarded 14 research proposals for more than $213K dollars in additional research related to these investigations. Each cluster's activities are described and an Appendix summarizes these achievements.

  20. Evaluation of a novel canine activity monitor for at-home physical activity analysis.

    Science.gov (United States)

    Yashari, Jonathan M; Duncan, Colleen G; Duerr, Felix M

    2015-07-04

    Accelerometers are motion-sensing devices that have been used to assess physical activity in dogs. However, the lack of a user-friendly, inexpensive accelerometer has hindered the widespread use of this objective outcome measure in veterinary research. Recently, a smartphone-based, affordable activity monitor (Whistle) has become available for measurement of at-home physical activity in dogs. The aim of this research was to evaluate this novel accelerometer. Eleven large breed, privately owned dogs wore a collar fitted with both the Whistle device and a previously validated accelerometer-based activity monitor (Actical) for a 24-h time period. Owners were asked to have their dogs resume normal daily activities. Total activity time obtained from the Whistle device in minutes was compared to the total activity count from the Actical device. Activity intensity from the Whistle device was calculated manually from screenshots of the activity bars displayed in the smartphone-application and compared to the activity count recorded by the Actical in the same 3-min time period. A total of 3740 time points were compared. There was a strong correlation between activity intensity of both devices for individual time points (Pearson's correlation coefficient 0.81, p battery life, the need for manual derivation of activity intensity data and data transfer, and the requirement of Wi-Fi and Bluetooth availability for data transmission.

  1. Cognitive tutoring induces widespread neuroplasticity and remediates brain function in children with mathematical learning disabilities.

    Science.gov (United States)

    Iuculano, Teresa; Rosenberg-Lee, Miriam; Richardson, Jennifer; Tenison, Caitlin; Fuchs, Lynn; Supekar, Kaustubh; Menon, Vinod

    2015-09-30

    Competency with numbers is essential in today's society; yet, up to 20% of children exhibit moderate to severe mathematical learning disabilities (MLD). Behavioural intervention can be effective, but the neurobiological mechanisms underlying successful intervention are unknown. Here we demonstrate that eight weeks of 1:1 cognitive tutoring not only remediates poor performance in children with MLD, but also induces widespread changes in brain activity. Neuroplasticity manifests as normalization of aberrant functional responses in a distributed network of parietal, prefrontal and ventral temporal-occipital areas that support successful numerical problem solving, and is correlated with performance gains. Remarkably, machine learning algorithms show that brain activity patterns in children with MLD are significantly discriminable from neurotypical peers before, but not after, tutoring, suggesting that behavioural gains are not due to compensatory mechanisms. Our study identifies functional brain mechanisms underlying effective intervention in children with MLD and provides novel metrics for assessing response to intervention.

  2. Plagiarism, Cheating and Research Integrity: Case Studies from a Masters Program in Peru.

    Science.gov (United States)

    Carnero, Andres M; Mayta-Tristan, Percy; Konda, Kelika A; Mezones-Holguin, Edward; Bernabe-Ortiz, Antonio; Alvarado, German F; Canelo-Aybar, Carlos; Maguiña, Jorge L; Segura, Eddy R; Quispe, Antonio M; Smith, Edward S; Bayer, Angela M; Lescano, Andres G

    2017-08-01

    Plagiarism is a serious, yet widespread type of research misconduct, and is often neglected in developing countries. Despite its far-reaching implications, plagiarism is poorly acknowledged and discussed in the academic setting, and insufficient evidence exists in Latin America and developing countries to inform the development of preventive strategies. In this context, we present a longitudinal case study of seven instances of plagiarism and cheating arising in four consecutive classes (2011-2014) of an Epidemiology Masters program in Lima, Peru, and describes the implementation and outcomes of a multifaceted, "zero-tolerance" policy aimed at introducing research integrity. Two cases involved cheating in graded assignments, and five cases correspond to plagiarism in the thesis protocol. Cases revealed poor awareness of high tolerance to plagiarism, poor academic performance, and widespread writing deficiencies, compensated with patchwriting and copy-pasting. Depending on the events' severity, penalties included course failure (6/7) and separation from the program (3/7). Students at fault did not engage in further plagiarism. Between 2011 and 2013, the Masters program sequentially introduced a preventive policy consisting of: (i) intensified research integrity and scientific writing education, (ii) a stepwise, cumulative writing process; (iii) honor codes; (iv) active search for plagiarism in all academic products; and (v) a "zero-tolerance" policy in response to documented cases. No cases were detected in 2014. In conclusion, plagiarism seems to be widespread in resource-limited settings and a greater response with educational and zero-tolerance components is needed to prevent it.

  3. Inventive Activity of Researchers: Cross-Country Rating Assessments

    Directory of Open Access Journals (Sweden)

    Tatyana Ivanovna Volkova

    2017-03-01

    Full Text Available In recent years, the study of the research capacity of the country and regions has become more active not only from the point of view of their leading components (personnel, financial, information, organizational, material-and-technical ones but also from the perspective of the assessment of productivity and effectiveness of researchers’ work. In the cross-country analysis, the certain highly aggregative parameters, which values, as a rule, are not in favour of Russia, are used. At the same time, at profound studying of this topic, these estimates cannot represent correctly the real trends of inventive activity in the scientific and technological sphere of the country and its regions. Moreover, the measurement of the researchers’ creative potential realization is carried out mainly through the assessment systems of their printing activity. Little attention is paid to the problem of the rating assessments of the researchers’ inventive and patent activity and its products from a cross-country perspective (especially to the detailed ones as well as to its institutional determinants. Therefore, the authors have chosen this subject-matter of the research. Its empirical basis is the statistical materials of both the national database and those which are recognized by the world scientific community. This research has both theoretical and methodological orientations. The purpose is the development of methodological and methodical tools of the research and assessment of researchers’ inventive activity including methodological support of cross-country comparative assessments. The authors have based the hypothesis on their previous research: in the conditions of the decreasing level of financial security, continuous reduction of a number of researchers, institutional restrictions and contradictions, the inventive activity of national researchers is still exist, and in a number of its leading parameters is implemented at the level of the advanced

  4. Polysaccharides from Traditional Chinese Medicines: Extraction, Purification, Modification, and Biological Activity.

    Science.gov (United States)

    Chen, Yun; Yao, Fangke; Ming, Ke; Wang, Deyun; Hu, Yuanliang; Liu, Jiaguo

    2016-12-13

    Traditional Chinese Medicine (TCM) has been used to treat diseases in China for thousands of years. TCM compositions are complex, using as their various sources plants, animals, fungi, and minerals. Polysaccharides are one of the active and important ingredients of TCMs. Polysaccharides from TCMs exhibit a wide range of biological activities in terms of immunity- modifying, antiviral, anti-inflammatory, anti-oxidative, and anti-tumor properties. With their widespread biological activities, polysaccharides consistently attract scientist's interests, and the studies often concentrate on the extraction, purification, and biological activity of TCM polysaccharides. Currently, numerous studies have shown that the modification of polysaccharides can heighten or change the biological activities, which is a new angle of polysaccharide research. This review highlights the current knowledge of TCM polysaccharides, including their extraction, purification, modification, and biological activity, which will hopefully provide profound insights facilitating further research and development.

  5. Diversity of two widespread Indo-Pacific demosponge species revisited

    OpenAIRE

    Erpenbeck, D.; Aryasari, R.; Benning, S.; Debitus, Cécile; Kaltenbacher, E.; Al-Aidaroos, A. M.; Schupp, P.; Hall, K.; Hooper, J. N. A.; Voigt, O.; de Voogd, N. J.; Worheide, G.

    2017-01-01

    The Indo-Pacific is the world's largest marine biogeographic region, covering the tropical and subtropical waters from the Red Sea in the Western Indian Ocean to the Easter Islands in the Pacific. It is characterized by a vast degree of biogeographic connectivity in particular in its marine realm. So far, usage of molecular tools rejected the presence of cosmopolitan or very widespread sponge species in several cases, supporting hypotheses on a higher level of endemism among marine invertebra...

  6. Research on Mobile Learning Activities Applying Tablets

    Science.gov (United States)

    Kurilovas, Eugenijus; Juskeviciene, Anita; Bireniene, Virginija

    2015-01-01

    The paper aims to present current research on mobile learning activities in Lithuania while implementing flagship EU-funded CCL project on application of tablet computers in education. In the paper, the quality of modern mobile learning activities based on learning personalisation, problem solving, collaboration, and flipped class methods is…

  7. On the research activities in reactor and neutron physics using the first egyptian research reactor

    International Nuclear Information System (INIS)

    Hassan, A.M.

    2000-01-01

    A review on the most important research activities in reactor and neutron physics using the first Egyptian Research Reactor (ET-RR-1) is given. An out look on: neutron cross-sections, neutron flux, neutron capture gamma-ray spectroscopy, neutron activation analysis, neutron diffraction and radiation shielding experiments, is presented

  8. IAEA activities supporting the applications of research reactors in 2013

    International Nuclear Information System (INIS)

    Peld, N.D.; Ridikas, D.

    2014-01-01

    As the underutilization of research reactors around the world persists as a primary topic of concern among facility owners and operators, the IAEA responded in 2013 with a broad range of activities to address the planning, execution and improvement of many experimental techniques. The revision of two critical documents for planning and diversifying a facility's portfolio of applications, TECDOC 1234 'The Applications of Research Reactors' and TECDOC 1212 'Strategic Planning for Research Reactors', is in progress in order to keep this information relevant, corresponding to the dynamism of experimental techniques and research capabilities. Related to the latter TECDOC, the IAEA convened a meeting in 2013 for the expert review of a number of strategic plans submitted by research reactor operators in developing countries. A number of activities focusing on specific applications are either continuing or beginning as well. In neutron activation analysis, a joint round of inter-comparison proficiency testing sponsored by the IAEA Technical Cooperation Department will be completed, and facility progress in measurement accuracy is described. Also, a training workshop in neutron imaging and Coordinated Research Projects in reactor benchmarks, automation of neutron activation analysis and neutron beam techniques for material testing intend to advance these activities as more beneficial services to researchers and other users. (author)

  9. Effect of information sharing on research and teaching activities of ...

    African Journals Online (AJOL)

    This study was designed to determine the effect of Information sharing on research and teaching activities of Academic Scientists in Federal Universities in the North- East Nigeria. Investigation was done on the activities of information sharing and the effect of information sharing on teaching and research activities. Survey ...

  10. BSp66 protease is widespread in the acrosomal region of sperm from several mammalian species

    International Nuclear Information System (INIS)

    Cesari, A.; Katunar, M.R.; Monclus, M.A.; Vincenti, A.; Fornes, M.W.

    2004-01-01

    Fertilization in mammals comprises a sequence of events leading to the fusion of sperm and oocyte membranes. Although proteases are known to be involved in this process, their role in fertilization is controversial. There is extensive work on the characterization of proteolytic systems, including serine proteases, which demonstrates that acrosomal proteases can be distinguished among the sperm of different mammalian species on the basis of the gelatin-hydrolyzing activity on SDS-PAGE by the quantity and variety of the enzymes. In this report, we investigated the occurrence and activity of the serine protease BSp66, previously characterized in bovine spermatozoa, in various mammalian sperm. A protein with a molecular mass of 66 kDa cross-reacted with heterologous antibodies against bovine BSp66 when sperm extracts of several mammalian species were analyzed by Western blot. In agreement, proteolytic activity corresponding to the molecular mass of BSp66 was detected by gelatin zymography in all the species analyzed. This protein was located on the acrosomal region of sperm cells by immunofluorescence methods. We concluded that BSp66 is widespread in mammalian sperm, with a conserved location in the acrosomal region

  11. Nine Challenges for e-Government Action Researchers

    DEFF Research Database (Denmark)

    Berger, Jesper Bull; Rose, Jeremy

    2015-01-01

    Action research is widespread in many of the background disciplines that underpin the e-Government field and is beginning to take root as a legitimate e-Government research method. Canonical Action Research (CAR)is the most widely used form of action research; however it relies on premises that c...

  12. Research Activities on Special Propulsion in BUAA

    International Nuclear Information System (INIS)

    Tang Haibin; Wang Haixing; Liu Chang; Xiang Min; Yao Jie; Liu Yu

    2007-01-01

    An overview is presented of special propulsion research carried out in Beijing University of Aeronautics and Astronautics of China. The research activities are supported by NSFC (National Natural Science Foundation of China), other governmental agencies and industrial partners, which include experimental, analytical and numerical work related to arcjet thrusters, ion thrusters, plasma sail and other new concept propulsions

  13. Research of fault activity in Japan

    International Nuclear Information System (INIS)

    Nohara, T.; Nakatsuka, N.; Takeda, S.

    2004-01-01

    Six hundreds and eighty earthquakes causing significant damage have been recorded since the 7. century in Japan. It is important to recognize faults that will or are expected to be active in future in order to help reduce earthquake damage, estimate earthquake damage insurance and siting of nuclear facilities. Such faults are called 'active faults' in Japan, the definition of which is a fault that has moved intermittently for at least several hundred thousand years and is expected to continue to do so in future. Scientific research of active faults has been ongoing since the 1930's. Many results indicated that major earthquakes and fault movements in shallow crustal regions in Japan occurred repeatedly at existing active fault zones during the past. After the 1995 Southern Hyogo Prefecture Earthquake, 98 active fault zones were selected for fundamental survey, with the purpose of efficiently conducting an active fault survey in 'Plans for Fundamental Seismic Survey and Observation' by the headquarters for earthquake research promotion, which was attached to the Prime Minister's office of Japan. Forty two administrative divisions for earthquake disaster prevention have investigated the distribution and history of fault activity of 80 active fault zones. Although earthquake prediction is difficult, the behaviour of major active faults in Japan is being recognised. Japan Nuclear Cycle Development Institute (JNC) submitted a report titled 'H12: Project to Establish the. Scientific and Technical Basis for HLW Disposal in Japan' to the Atomic Energy Commission (AEC) of Japan for official review W. The Guidelines, which were defined by AEC, require the H12 Project to confirm the basic technical feasibility of safe HLW disposal in Japan. In this report the important issues relating to fault activity were described that are to understand the characteristics of current fault movements and the spatial extent and magnitude of the effects caused by these movements, and to

  14. CNRS researchers' popularization activities: a progress report

    Directory of Open Access Journals (Sweden)

    Yves Croissant

    2007-09-01

    Full Text Available We have analyzed the popularization activities undertaken by ten thousand CNRS researchers by means of their annual reports for the years 2004, 2005 and 2006. This is the first time that such an extensive statistical study on science popularization practices is carried out. Our main findings are : - the majority of researchers is not involved in popularization (51% has not done any popularization over the three-year period, two thirds have been involved in no more than one popularization action. - popularization practices are extremely diverse, both at the individual level (we have identified three subpopulations that feature distinctive attitudes towards popularization, and at the level of scientific disciplines (researchers in Humanities are twice as active as the average, as well as in laboratories or geographical regions. - the number of actions reported in 2005 greatly increased compared to 2004 (+ 26%, while they slightly diminished in 2006.

  15. Polysaccharides from Traditional Chinese Medicines: Extraction, Purification, Modification, and Biological Activity

    Directory of Open Access Journals (Sweden)

    Yun Chen

    2016-12-01

    Full Text Available Traditional Chinese Medicine (TCM has been used to treat diseases in China for thousands of years. TCM compositions are complex, using as their various sources plants, animals, fungi, and minerals. Polysaccharides are one of the active and important ingredients of TCMs. Polysaccharides from TCMs exhibit a wide range of biological activities in terms of immunity- modifying, antiviral, anti-inflammatory, anti-oxidative, and anti-tumor properties. With their widespread biological activities, polysaccharides consistently attract scientist's interests, and the studies often concentrate on the extraction, purification, and biological activity of TCM polysaccharides. Currently, numerous studies have shown that the modification of polysaccharides can heighten or change the biological activities, which is a new angle of polysaccharide research. This review highlights the current knowledge of TCM polysaccharides, including their extraction, purification, modification, and biological activity, which will hopefully provide profound insights facilitating further research and development.

  16. 48 CFR 27.408 - Cosponsored research and development activities.

    Science.gov (United States)

    2010-10-01

    ....408 Cosponsored research and development activities. (a) In contracts involving cosponsored research... objectives of the contract. Since the purpose of the cosponsored research and development, the legitimate... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Cosponsored research and...

  17. Activation Analysis and Nuclear Research in Burma

    Energy Technology Data Exchange (ETDEWEB)

    Thiele, R. W.

    1971-07-01

    Research endeavours in the field of Nuclear Sciences in Burma appear to be concentrated in three main Institutions. These are the Chemistry and Physics Departments of the Rangoon Arts & Science University and the Union of Burma Applied Research Institute (UBARI). In view of possible forthcoming developments an expanded research programme, which is to be implemented on the basis of a five year plan, has been drawn up. Research topics included in this programme are predominantly of practical interest and aimed at a contribution by nuclear methods, in particular activation analysis, to the technological and industrial needs of the country.

  18. Summary of Chernobyl followup research activities

    International Nuclear Information System (INIS)

    1992-06-01

    In NUREG-1251, ''Implications of the Accident at Chernobyl for Safety Regulation of Commercial Nuclear Power Plants in the United States,'' April 1989, the NRC staff concluded that no immediate changes in NRC's regulations regarding design or operation of US commercial reactors were needed; however, it recommended that certain issues be considered further. NRC's Chernobyl followup research program consisted of the research tasks undertaken in response to the recommendations in NUREG-1251. It included 23 tasks that addressed potential lessons to be learned from the Chernobyl accident. This report presents summaries of NRC's Chernobyl followup research tasks. For each task, the Chernobyl-related issues are indicated, the work is described, and the staff's findings and conclusions are presented. More detailed reports concerning the work are referenced where applicable. This report closes out NRC's Chernobyl followup research program as such, but additional research will be conducted on some issues as needed. The report includes remarks concerning significant further activity with respect to the issues addressed

  19. Preoperative widespread pain sensitization and chronic pain after hip and knee replacement: a cohort analysis

    Science.gov (United States)

    Wylde, Vikki; Sayers, Adrian; Lenguerrand, Erik; Gooberman-Hill, Rachael; Pyke, Mark; Beswick, Andrew D.; Dieppe, Paul; Blom, Ashley W.

    2015-01-01

    Abstract Chronic pain after joint replacement is common, affecting approximately 10% of patients after total hip replacement (THR) and 20% of patients after total knee replacement (TKR). Heightened generalized sensitivity to nociceptive input could be a risk factor for the development of this pain. The primary aim of this study was to investigate whether preoperative widespread pain sensitivity was associated with chronic pain after joint replacement. Data were analyzed from 254 patients receiving THR and 239 patients receiving TKR. Pain was assessed preoperatively and at 12 months after surgery using the Western Ontario and McMaster Universities Osteoarthritis Pain Scale. Preoperative widespread pain sensitivity was assessed through measurement of pressure pain thresholds (PPTs) at the forearm using an algometer. Statistical analysis was conducted using linear regression and linear mixed models, and adjustments were made for confounding variables. In both the THR and TKR cohort, lower PPTs (heightened widespread pain sensitivity) were significantly associated with higher preoperative pain severity. Lower PPTs were also significantly associated with higher pain severity at 12 months after surgery in the THR cohort. However, PPTs were not associated with the change in pain severity from preoperative to 12 months postoperative in either the TKR or THR cohort. These findings suggest that although preoperative widespread pressure pain sensitivity is associated with pain severity before and after joint replacement, it is not a predictor of the amount of pain relief that patients gain from joint replacement surgery, independent of preoperative pain severity. PMID:25599300

  20. Evidence of small-fiber polyneuropathy in unexplained, juvenile-onset, widespread pain syndromes.

    Science.gov (United States)

    Oaklander, Anne Louise; Klein, Max M

    2013-04-01

    We tested the hypothesis that acquired small-fiber polyneuropathy (SFPN), previously uncharacterized in children, contributes to unexplained pediatric widespread pain syndromes. Forty-one consecutive patients evaluated for unexplained widespread pain beginning before age 21 had medical records comprehensively analyzed regarding objective diagnostic testing for SFPN (neurodiagnostic skin biopsy, nerve biopsy, and autonomic function testing), plus histories, symptoms, signs, other tests, and treatments. Healthy, demographically matched volunteers provided normal controls for SFPN tests. Age at illness onset averaged 12.3 ± 5.7 years; 73% among this poly-ethnic sample were female (P = .001). Sixty-eight percent were chronically disabled, and 68% had hospitalizations. Objective testing diagnosed definite SFPN in 59%, probable SFPN in 17%, and possible SFPN in 22%. Only 1 of 41 had entirely normal SFPN test results. Ninety-eight percent of patients had other somatic complaints consistent with SFPN dysautonomia (90% cardiovascular, 82% gastrointestinal, and 34% urologic), 83% reported chronic fatigue, and 63% had chronic headache. Neurologic examinations identified reduced sensation in 68% and vasomotor abnormalities in 55%, including 23% with erythromelalgia. Exhaustive investigations for SFPN causality identified only history of autoimmune illnesses in 33% and serologic markers of disordered immunity in 89%. Treatment with corticosteroids and/or intravenous immune globulin objectively and subjectively benefited 80% of patients (12/15). More than half among a large series of patients with childhood-onset, unexplained chronic widespread pain met rigorous, multitest, diagnostic criteria for SFPN, which extends the age range of acquired SFPN into early childhood. Some cases appeared immune-mediated and improved with immunomodulatory therapies.

  1. Regional pest suppression associated with widespread Bt maize adoption benefits vegetable growers.

    Science.gov (United States)

    Dively, Galen P; Venugopal, P Dilip; Bean, Dick; Whalen, Joanne; Holmstrom, Kristian; Kuhar, Thomas P; Doughty, Hélène B; Patton, Terry; Cissel, William; Hutchison, William D

    2018-03-27

    Transgenic crops containing the bacterium Bacillus thuringiensis (Bt) genes reduce pests and insecticide usage, promote biocontrol services, and economically benefit growers. Area-wide Bt adoption suppresses pests regionally, with declines expanding beyond the planted Bt crops into other non-Bt crop fields. However, the offsite benefits to growers of other crops from such regional suppression remain uncertain. With data spanning 1976-2016, we demonstrate that vegetable growers benefit via decreased crop damage and insecticide applications in relation to pest suppression in the Mid-Atlantic United States. We provide evidence for the regional suppression of Ostrinia nubilalis (Hübner), European corn borer, and Helicoverpa zea (Boddie), corn earworm, populations in association with widespread Bt maize adoption (1996-2016) and decreased economic levels for injury in vegetable crops [peppers ( Capsicum annuum L.), green beans ( Phaseolus vulgaris L.), and sweet corn ( Zea mays L., convar. saccharata )] compared with the pre-Bt period (1976-1995). Moth populations of both species significantly declined in association with widespread Bt maize (field corn) adoption, even as increased temperatures buffered the population reduction. We show marked decreases in the number of recommended insecticidal applications, insecticides applied, and O. nubilalis damage in vegetable crops in association with widespread Bt maize adoption. These offsite benefits to vegetable growers in the agricultural landscape have not been previously documented, and the positive impacts identified here expand on the reported ecological effects of Bt adoption. Our results also underscore the need to account for offsite economic benefits of pest suppression, in addition to the direct economic benefits of Bt crops.

  2. Recent NRC research activities addressing valve and pump issues

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, D.L.

    1996-12-01

    The mission of the U.S. Nuclear Regulatory Commission (NRC) is to ensure the safe design, construction, and operation of commercial nuclear power plants and other facilities in the U.S.A. One of the main roles that the Office of Nuclear Regulatory Research (RES) plays in achieving the NRC mission is to plan, recommend, and implement research programs that address safety and technical issues deemed important by the NRC. The results of the research activities provide the bases for developing NRC positions or decisions on these issues. Also, RES performs confirmatory research for developing the basis to evaluate industry responses and positions on various regulatory requirements. This presentation summarizes some recent RES supported research activities that have addressed safety and technical issues related to valves and pumps. These activities include the efforts on determining valve and motor-operator responses under dynamic loads and pressure locking events, evaluation of monitoring equipment, and methods for detecting and trending aging of check valves and pumps. The role that RES is expected to play in future years to fulfill the NRC mission is also discussed.

  3. Becker muscular dystrophy with widespread muscle hypertrophy and a non-sense mutation of exon 2

    DEFF Research Database (Denmark)

    Witting, Nanna; Duno, M; Vissing, J

    2013-01-01

    Becker muscular dystrophy features progressive proximal weakness, wasting and often focal hypertrophy. We present a patient with pain and cramps from adolescence. Widespread muscle hypertrophy, preserved muscle strength and a 10-20-fold raised CPK were noted. Muscle biopsy was dystrophic......, and Western blot showed a 95% reduction of dystrophin levels. Genetic analyses revealed a non-sense mutation in exon 2 of the dystrophin gene. This mutation is predicted to result in a Duchenne phenotype, but resulted in a mild Becker muscular dystrophy with widespread muscle hypertrophy. We suggest...

  4. Pressure Vessel Steel Research: Belgian Activities

    International Nuclear Information System (INIS)

    Van Walle, E.; Fabry, A.; Ait Abderrahim, H.; Chaouadi, R.; D'hondt, P.; Puzzolante, J.L.; Van de Velde, J.; Van Ransbeeck, T.; Gerard, R.

    1994-03-01

    A review of the Belgian research activities on Nuclear Reactor Pressure Vessel Steels (RPVS) and on related Neutron Dosimetry Aspects is presented. Born out of the surveillance programmes of the Belgian nuclear power plants, this research has lead to the development of material saving techniques, like reconstitution and miniaturization, and to improved neutron dosimetry techniques. A physically- justified RPVS fracture toughness indexation methodology, supported by micro-mechanistic modelling, is based on the elaborate use of the instrumented Charpy impact signal. Computational tools for neutron dosimetry allow to reduce the uncertainties on surveillance capsule fluences significantly

  5. Pressure Vessel Steel Research: Belgian Activities

    Energy Technology Data Exchange (ETDEWEB)

    Van Walle, E; Fabry, A; Ait Abderrahim, H; Chaouadi, R; D` hondt, P; Puzzolante, J L; Van de Velde, J; Van Ransbeeck, T [Centre d` Etude de l` Energie Nucleaire, Mol (Belgium); Gerard, R [TRACTEBEL, Brussels (Belgium)

    1994-03-01

    A review of the Belgian research activities on Nuclear Reactor Pressure Vessel Steels (RPVS) and on related Neutron Dosimetry Aspects is presented. Born out of the surveillance programmes of the Belgian nuclear power plants, this research has lead to the development of material saving techniques, like reconstitution and miniaturization, and to improved neutron dosimetry techniques. A physically- justified RPVS fracture toughness indexation methodology, supported by micro-mechanistic modelling, is based on the elaborate use of the instrumented Charpy impact signal. Computational tools for neutron dosimetry allow to reduce the uncertainties on surveillance capsule fluences significantly.

  6. Teacher research as self-study and collaborative activity

    OpenAIRE

    Gade, Sharada

    2015-01-01

    This article highlights two insightful methods for advancing teacher research: practitioner self-study in relation to a range of texts, with which to examine one’s educational landscape; and classroom interventions conceived as a Vygotskian activity, via teacher-researcher collaboration. Both approaches allow teachers and collaborating researchers to share individual expertise across institutional boundaries and engage in creative local action.

  7. Scientific activities 1980 Nuclear Research Center ''Democritos''

    International Nuclear Information System (INIS)

    1982-01-01

    The scientific activities and achievements of the Nuclear Research Center Democritos for the year 1980 are presented in the form of a list of 76 projects giving title, objectives, responsible of each project, developed activities and the pertaining lists of publications. The 16 chapters of this work cover the activities of the main Divisions of the Democritos NRC: Electronics, Biology, Physics, Chemistry, Health Physics, Reactor, Scientific Directorate, Radioisotopes, Environmental Radioactivity, Soil Science, Computer Center, Uranium Exploration, Medical Service, Technological Applications, Radioimmunoassay and Training. (N.C.)

  8. A plan for research by the atmospheric research section in support of Ontario Hydro's nuclear activities

    International Nuclear Information System (INIS)

    Ogram, G.L.; Melo, O.T.

    1984-01-01

    A plan for nuclear studies by the Atmospheric Research Section is presented. The need for research is discussed and research objectives are established. Recommended research activities include the study of fundamental processes governing the fate of emissions released to the atmosphere by Hydro's nuclear facilities and the development of improved transport models describing the fate of these emissions. A Sectional goal of providing technical expertise in the atmospheric sciences in support of Ontario Hydro's present and future nuclear activities is proposed. The plan covers a five-year time frame (1984-1988)

  9. Summary reports of activities under visiting research program, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    This report contains summary reports of activities under visiting research program, 1995 carried out in the Research Reactor Institute, Kyoto University in 1995. As cooperative activities of KUR, 9 projects and 91 ordinary researches are described in their summaries, with 10 ordinary researches in KUCA cooperative activities. Titles of the 9 projects are development of biological effect analysis of monochromatic neutron spectrum field, study on optimization of bottle condition in ultra cold neutron fission experiment, feature improvement of KUR-ISOL and nuclear spectroscopy and nuclear physics using it, fundamental study on development of new compound for thermal neutron trapping therapy and expansion of its adopting illness, study on properties of synthetic metal using nuclear procedure, neutron diffraction of magnetic substances under the extreme conditions (high pressure, high magnetic field), study on movement in environment of harmful substances, fundamental study on radiation protection against controllable radiation in KUR, and dynamic property study of metal materials using low speed neutron scattering method. (G.K.)

  10. Game-Based Virtual Worlds as Decentralized Virtual Activity Systems

    Science.gov (United States)

    Scacchi, Walt

    There is widespread interest in the development and use of decentralized systems and virtual world environments as possible new places for engaging in collaborative work activities. Similarly, there is widespread interest in stimulating new technological innovations that enable people to come together through social networking, file/media sharing, and networked multi-player computer game play. A decentralized virtual activity system (DVAS) is a networked computer supported work/play system whose elements and social activities can be both virtual and decentralized (Scacchi et al. 2008b). Massively multi-player online games (MMOGs) such as World of Warcraft and online virtual worlds such as Second Life are each popular examples of a DVAS. Furthermore, these systems are beginning to be used for research, deve-lopment, and education activities in different science, technology, and engineering domains (Bainbridge 2007, Bohannon et al. 2009; Rieber 2005; Scacchi and Adams 2007; Shaffer 2006), which are also of interest here. This chapter explores two case studies of DVASs developed at the University of California at Irvine that employ game-based virtual worlds to support collaborative work/play activities in different settings. The settings include those that model and simulate practical or imaginative physical worlds in different domains of science, technology, or engineering through alternative virtual worlds where players/workers engage in different kinds of quests or quest-like workflows (Jakobsson 2006).

  11. Bling My Research! A Mock Grant Panel Activity Illustrating the Importance of Basic Research

    Science.gov (United States)

    Leander, Celeste A.; Whitton, Jeannette

    2010-01-01

    First-year university students have misconceptions about the source and dynamics of publicly funded research money. We designed an activity in which students take part in a mock grant panel. The results indicated a strong tendency toward student funding of applied medical research at the expense of basic research. Exposure to a few examples of…

  12. University Research and Development Activities: The Federal Income Tax Consequences of Research Contracts, Research Subsidiaries and Joint Ventures.

    Science.gov (United States)

    Kertz, Consuelo Lauda; Hasson, James K., Jr.

    1986-01-01

    Features of the federal income tax law applying to income received from commercially funded university-based scientific research and development activities are discussed, including: industry-sponsored research contracts, separately incorporated entities, partnerships and joint ventures, subsidiaries and unrelated income consequences of…

  13. Encouraging entrepreneurship in university labs: Research activities, research outputs, and early doctorate careers.

    Science.gov (United States)

    Roach, Michael

    2017-01-01

    This paper investigates how the encouragement of entrepreneurship within university research labs relates with research activities, research outputs, and early doctorate careers. Utilizing a panel survey of 6,840 science & engineering doctoral students at 39 R1 research universities, this study shows that entrepreneurship is widely encouraged across university research labs, ranging from 54% in biomedical engineering to 18% in particle physics, while only a small share of labs openly discourage entrepreneurship, from approximately 3% in engineering to approximately 12% in the life sciences. Within fields, there is no difference between labs that encourage entrepreneurship and those that do not with respect to basic research activity and the number of publications. At the same time, labs that encourage entrepreneurship are significantly more likely to report invention disclosures, particularly in engineering where such labs are 41% more likely to disclose inventions. With respect to career pathways, PhDs students in labs that encourage entrepreneurship do not differ from other PhDs in their interest in academic careers, but they are 87% more likely to be interested in careers in entrepreneurship and 44% more likely to work in a startup after graduation. These results persist even when accounting for individuals' pre-PhD interest in entrepreneurship and the encouragement of other non-academic industry careers.

  14. Encouraging entrepreneurship in university labs: Research activities, research outputs, and early doctorate careers

    Science.gov (United States)

    2017-01-01

    This paper investigates how the encouragement of entrepreneurship within university research labs relates with research activities, research outputs, and early doctorate careers. Utilizing a panel survey of 6,840 science & engineering doctoral students at 39 R1 research universities, this study shows that entrepreneurship is widely encouraged across university research labs, ranging from 54% in biomedical engineering to 18% in particle physics, while only a small share of labs openly discourage entrepreneurship, from approximately 3% in engineering to approximately 12% in the life sciences. Within fields, there is no difference between labs that encourage entrepreneurship and those that do not with respect to basic research activity and the number of publications. At the same time, labs that encourage entrepreneurship are significantly more likely to report invention disclosures, particularly in engineering where such labs are 41% more likely to disclose inventions. With respect to career pathways, PhDs students in labs that encourage entrepreneurship do not differ from other PhDs in their interest in academic careers, but they are 87% more likely to be interested in careers in entrepreneurship and 44% more likely to work in a startup after graduation. These results persist even when accounting for individuals’ pre-PhD interest in entrepreneurship and the encouragement of other non-academic industry careers. PMID:28178270

  15. Transient widespread cortical and splenial lesions in acute encephalitis/encephalopathy associated with primary Epstein–Barr virus infection

    Directory of Open Access Journals (Sweden)

    Shuo Zhang

    2016-01-01

    Full Text Available Infection with Epstein–Barr virus (EBV is very common and usually occurs in childhood or early adulthood. Encephalitis/encephalopathy is an uncommon but serious neurological complication of EBV. A case of EBV-associated encephalitis/encephalopathy with involvement of reversible widespread cortical and splenial lesions is presented herein. An 8-year-old Chinese girl who presented with fever and headache, followed by seizures and drowsiness, was admitted to the hospital. Magnetic resonance imaging revealed high signal intensities on diffusion-weighted imaging in widespread cortical and splenial lesions. The clinical and laboratory examination results together with the unusual radiology findings suggested acute encephalitis/encephalopathy due to primary EBV infection. After methylprednisolone pulse therapy together with ganciclovir, the patient made a full recovery without any brain lesions. The hallmark clinical–radiological features of this patient included severe encephalitis/encephalopathy at onset, the prompt and complete recovery, and rapidly reversible widespread involvement of the cortex and splenium. Patients with EBV encephalitis/encephalopathy who have multiple lesions, even with the widespread involvement of cortex and splenium of the corpus callosum, may have a favorable outcome with complete disappearance of all brain lesions.

  16. Coordinated research activities: Annual report and statistics for 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-15

    In 2007, a total of Euro 6 606 194 were obligated for the Agency's Coordinated Research Activities (Euro 6 515 957 from the regular budget and Euro 90 237 from extrabudgetary resources). Most of the Coordinated Research Activities are carried out via Coordinated Research Projects (CRPs) which bring together research institutes in both developing and developed Member States to collaborate on research topics of common interest. At the end of 2007, work was being carried out on 115 CRPs, 37 in Major Programme 1 - Nuclear Power, Fuel Cycle and Nuclear Science, 71 in Major Programme 2 - Nuclear Techniques for Development and Environmental Protection, and 7 in Major Programme 3 - Nuclear Safety and Security. The total amount obligated for these activities in 2007 was 15% more than in 2006, largely due to the implementation of 28 new CRPs. At the end of 2007 work was being carried out under 976 contracts and 562 agreements with institutes in 110 Member States. 72% of the funds obligated for contracts in 2007 were in respect of institutions in developing countries, primarily in the areas of food and agriculture and human health. During 2007, 21% of the Chief Scientific Investigators participating in Agency CRPs were female researchers. Efforts will continue to increase the participation of women and younger researcher in the Coordinated Research Activities. The forty two completed CRPs evaluated in Appendix E resulted in 9 PhDs, one masters degree and in the publishing of about 800 articles and reports, scientific papers, proceedings of scientific conferences and contribution to international conferences, as well as 13 IAEA TECDOCs, and various scientific databases and websites. Detailed evaluation reports on the outputs, effectiveness, impact, recommended future action, and resulting publications of these completed CRPs are included in in Appendix E of this report. (author)

  17. Coordinated research activities: Annual report and statistics for 2007

    International Nuclear Information System (INIS)

    2008-07-01

    In 2007, a total of Euro 6 606 194 were obligated for the Agency's Coordinated Research Activities (Euro 6 515 957 from the regular budget and Euro 90 237 from extrabudgetary resources). Most of the Coordinated Research Activities are carried out via Coordinated Research Projects (CRPs) which bring together research institutes in both developing and developed Member States to collaborate on research topics of common interest. At the end of 2007, work was being carried out on 115 CRPs, 37 in Major Programme 1 - Nuclear Power, Fuel Cycle and Nuclear Science, 71 in Major Programme 2 - Nuclear Techniques for Development and Environmental Protection, and 7 in Major Programme 3 - Nuclear Safety and Security. The total amount obligated for these activities in 2007 was 15% more than in 2006, largely due to the implementation of 28 new CRPs. At the end of 2007 work was being carried out under 976 contracts and 562 agreements with institutes in 110 Member States. 72% of the funds obligated for contracts in 2007 were in respect of institutions in developing countries, primarily in the areas of food and agriculture and human health. During 2007, 21% of the Chief Scientific Investigators participating in Agency CRPs were female researchers. Efforts will continue to increase the participation of women and younger researcher in the Coordinated Research Activities. The forty two completed CRPs evaluated in Appendix E resulted in 9 PhDs, one masters degree and in the publishing of about 800 articles and reports, scientific papers, proceedings of scientific conferences and contribution to international conferences, as well as 13 IAEA TECDOCs, and various scientific databases and websites. Detailed evaluation reports on the outputs, effectiveness, impact, recommended future action, and resulting publications of these completed CRPs are included in in Appendix E of this report. (author)

  18. Widespread Inhibition of Posttranscriptional Splicing Shapes the Cellular Transcriptome following Heat Shock

    Directory of Open Access Journals (Sweden)

    Reut Shalgi

    2014-06-01

    Full Text Available During heat shock and other proteotoxic stresses, cells regulate multiple steps in gene expression in order to globally repress protein synthesis and selectively upregulate stress response proteins. Splicing of several mRNAs is known to be inhibited during heat stress, often meditated by SRp38, but the extent and specificity of this effect have remained unclear. Here, we examined splicing regulation genome-wide during heat shock in mouse fibroblasts. We observed widespread retention of introns in transcripts from ∼1,700 genes, which were enriched for tRNA synthetase, nuclear pore, and spliceosome functions. Transcripts with retained introns were largely nuclear and untranslated. However, a group of 580+ genes biased for oxidation reduction and protein folding functions continued to be efficiently spliced. Interestingly, these unaffected transcripts are mostly cotranscriptionally spliced under both normal and stress conditions, whereas splicing-inhibited transcripts are mostly spliced posttranscriptionally. Altogether, our data demonstrate widespread repression of splicing in the mammalian heat stress response, disproportionately affecting posttranscriptionally spliced genes.

  19. Summary reports of activities under visiting research program (1993)

    International Nuclear Information System (INIS)

    1993-10-01

    The summary reports of activities under visiting research program in the Research Reactor Institute, Kyoto University, in fiscal year 1992 are included. In this report, 104 summaries of researches using the Kyoto University Reactor (KUR) and 9 summaries of the researches using the Kyoto University Critical Assembly (KUCA) are collected. (J.P.N.)

  20. 48 CFR 927.408 - Cosponsored research and development activities.

    Science.gov (United States)

    2010-10-01

    ... Cosponsored research and development activities. Because of the Department of Energy's statutory duties to disseminate data first produced under its contracts for research, development, and demonstration, the... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Cosponsored research and...

  1. 38 CFR 1.488 - Research activities.

    Science.gov (United States)

    2010-07-01

    ... any potential risks to patient confidentiality posed by the disclosure of records. (b) A person... PROVISIONS Disclosures Without Patient Consent § 1.488 Research activities. Subject to the provisions of 38 U... requirements of § 1.466 of this part (or more stringent requirements); and (ii) Will not be redisclosed except...

  2. Activity report of the Neutrino Research Group. Year 2006

    International Nuclear Information System (INIS)

    2007-01-01

    For the last two decades, neutrino physics has been producing major discoveries including neutrino oscillations. These results gave clear confirmation that active neutrinos oscillate and therefore have mass with three different mass states. This is a very important result showing that the Minimal Standard Model is incomplete and requires an extension which is not yet known. The neutrino research field is very broad and active, at the frontier of today's particle physics. The Neutrino Research Group (GDR) was created in January 2005 with the aim of gathering CEA and CNRS research teams working on Neutrino Physics on experimental or theoretical level. This document is the 2006 activity report of the research group, two years after its creation. It presents the results of the 5 working groups: 1 - Determination of neutrino parameters; 2 - Physics beyond the standard model; 3 - Neutrinos in the universe; 4 - Accelerators, detection means, R and D and valorisation; 5 - Common tools to all working groups. The proposed neutrino physics road-map and the actual and future short-, medium- and long-term projects are presented in appendixes. The Neutrino research group organization, the Memphys specific mission group, the research group participating laboratories and teams, as well as the Memphys project are presented too

  3. Recent Activities on the Experimental Research Programme Using Small Tokamaks

    International Nuclear Information System (INIS)

    Gryaznevich, M. P.; Bosco, E. del; Malaquias, A.; Mank, G.; Oost, G. van

    2006-01-01

    A new concept of interactive co-ordinated research using small tokamaks in the mainstream fusion science areas, in testing of new diagnostics, materials and technologies as well as in education, training and broadening of the geography of fusion research in the scope of the IAEA Co-ordinated Research Project (CRP) is discussed in this paper. Besides the presentation of the recent activities on the experimental research programme using small tokamaks and scientific results achieved at the participating laboratories, information is provided about the organisation of the co-ordinated research project. Future plans of the co-ordinated activities within the CRP are discussed

  4. Termination of past nuclear activities at the nuclear research institute

    International Nuclear Information System (INIS)

    Janzekovic, H.; Krizman, M.

    2006-01-01

    Many countries, particularly in Europe, started with nuclear programs in the fifties of the last century. As a consequence nuclear research institutes were established, among them also the Institute Jozef Stefan (IJS) in Slovenia. The nuclear activities at the IJS were related to the development of uranium ore processing technology and technologies comprising uranium oxide and hexafluoride. After very intensive period of nuclear activities the decline began step by step due to different reasons. Various approaches of the termination and decommissioning of facilities were used. The inspectors of the Slovenian Nuclear Safety Administration (SNSA), the responsible authority, started intensive activities at the IJS at the end of 2004. All together 22 research laboratories or research units were included in the inspection program and around 50 researchers of the IJS were involved into the inspection procedures. The inspection was very intensive in the laboratories and storages where past nuclear activities took place and were later on abandoned. As a result several contaminated equipments and sites in addition to around 200 unregistered sources were found. The majority of these sources is related to past nuclear activities. The inspection program related to the terminated research activities is still in progress. The IJS immediately started with the remediation activities including the development of methodology related to decontamination of radioactive liquids. The decontamination of two nuclear laboratories and three different storages of radioactive waste at its sites is in progress. Sixty of the above mentioned sources have been already stored in the Central Interim Storage for Radioactive Waste. (author)

  5. Conceptualizing Policy Work as Activity and Field of Research

    OpenAIRE

    Jan Kohoutek; Martin Nekola; Vilém Novotný

    2013-01-01

    The area of policy work and policy workers within government bureaucracies is encompassing a large field of activities and research. This article aims to provide a synthesised perspective on policy work in relating theoretical and empirical accounts of policy workers, identifying points of convergence and linking them to essential assumptions on research in policy work. We conceptualize policy work as activity within government bureaucracies from three interrelated perspectives: the professio...

  6. Multimodal and widespread somatosensory abnormalities in persistent shoulder pain in the first 6 months after stroke: an exploratory study

    NARCIS (Netherlands)

    Roosink, M.; van Dongen, R.T.; Buitenweg, J.R.; Renzenbrink, G.J.; Geurts, A.C.H.; IJzerman, M.J.

    2012-01-01

    Roosink M, Van Dongen RT, Buitenweg JR, Renzenbrink GJ, Geurts AC, IJzerman MJ. Multimodal and widespread somatosensory abnormalities in persistent shoulder pain in the first 6 months after stroke: an exploratory study. OBJECTIVE: To explore the role of multimodal and widespread somatosensory

  7. Music therapists' research activity and utilization barriers: a survey of the membership.

    Science.gov (United States)

    Waldon, Eric G

    2015-01-01

    Music therapists have access to a rapidly expanding body of research supporting the use of music-based interventions. What is not known is the extent to which music therapists access these resources and what factors may prevent them from incorporating research findings into clinical work. After constructing the Music Therapists' Research Activity and Utilization Barrier (MTRAUB) database, the purposes of this study involved: assessing the extent to which American Music Therapy Association (AMTA) members engage in certain research-related activities; and identifying respondents' perceived barriers to integrating research into clinical practice. This study employed a quantitative, non-experimental approach using an online survey. Respondents included professional, associate, student/graduate student, retired, inactive, and honorary life members of AMTA. Instrumentation involved a researcher-designed Background Questionnaire as well as the Barriers to Research Utilization Scale (BARRIERS; Funk, Champagne, Wiese, & Tornquist, 1991), a tool designed to assess perceived barriers to incorporating research into practice. Of the 3,194 survey invitations distributed, 974 AMTA members replied (a response rate of 30%). Regarding research-related activities, descriptive findings indicate that journal reading is the most frequently reported research-related activity while conducting research is the least frequently reported activity. Results from the BARRIERS Scale indicated that Organizational and Communication factors are perceived as interfering most prominently with the ability to utilize research in clinical practice. Findings suggest that research-related activity and perceived barriers vary as a function of educational attainment, work setting, and occupational role. The author discusses these differential findings in detail, suggests supportive mechanisms to encourage increased research activity and utilization, and offers recommendations for further analysis of the

  8. Device-based monitoring in physical activity and public health research

    International Nuclear Information System (INIS)

    Bassett, David R

    2012-01-01

    Measurement of physical activity is important, given the vital role of this behavior in physical and mental health. Over the past quarter of a century, the use of small, non-invasive, wearable monitors to assess physical activity has become commonplace. This review is divided into three sections. In the first section, a brief history of physical activity monitoring is provided, along with a discussion of the strengths and weaknesses of different devices. In the second section, recent applications of physical activity monitoring in physical activity and public health research are discussed. Wearable monitors are being used to conduct surveillance, and to determine the extent and distribution of physical activity and sedentary behaviors in populations around the world. They have been used to help clarify the dose–response relation between physical activity and health. Wearable monitors that provide feedback to users have also been used in longitudinal interventions to motivate research participants and to assess their compliance with program goals. In the third section, future directions for research in physical activity monitoring are discussed. It is likely that new developments in wearable monitors will lead to greater accuracy and improved ease-of-use. (paper)

  9. Three Dimensions of Learning: Experiential Activity for Engineering Innovation Education and Research

    Science.gov (United States)

    Killen, Catherine P.

    2015-01-01

    This paper outlines a novel approach to engineering education research that provides three dimensions of learning through an experiential class activity. A simulated decision activity brought current research into the classroom, explored the effect of experiential activity on learning outcomes and contributed to the research on innovation decision…

  10. Predictors of outcome of multidisciplinary treatment in chronic widespread pain: an observational study

    NARCIS (Netherlands)

    de Rooij, A.; van der Leeden, M.; Roorda, L.D.; Steultjens, M.P.M.; Dekker, J.

    2013-01-01

    Background: The effectiveness of multidisciplinary treatment in chronic widespread pain (CWP) is limited. The considerable heterogeneity among patients is a likely explanation. Knowledge on predictors of the outcome of multidisciplinary treatment can help to optimize treatment effectiveness. The

  11. The tad locus: postcards from the widespread colonization island.

    Science.gov (United States)

    Tomich, Mladen; Planet, Paul J; Figurski, David H

    2007-05-01

    The Tad (tight adherence) macromolecular transport system, which is present in many bacterial and archaeal species, represents an ancient and major new subtype of type II secretion. The tad genes are present on a genomic island named the widespread colonization island (WCI), and encode the machinery that is required for the assembly of adhesive Flp (fimbrial low-molecular-weight protein) pili. The tad genes are essential for biofilm formation, colonization and pathogenesis in the genera Aggregatibacter (Actinobacillus), Haemophilus, Pasteurella, Pseudomonas, Yersinia, Caulobacter and perhaps others. Here we review the structure, function and evolution of the Tad secretion system.

  12. Report on the IRSN's investigations following the widespread detection of 106Ru in Europe early October 2017

    International Nuclear Information System (INIS)

    2018-01-01

    Ruthenium-106 ( 106 Ru) is an anthropogenic radionuclide which is usually not observed in the atmosphere. Early October 2017, it was detected in almost all European countries. Observed activities ranged from a few μBq/m 3 to about 150 mBq/m 3 . Although, these concentrations did not pose any health or environmental issues, this widespread detection suggested that the source-term must have been quite high. Taken into account all these elements, IRSN decided to perform further investigations in order (1) to identify the possible location of the source, 2) to assess the total activity released and the release duration and 3) to understand the process that could be at the origin of the release of 106 Ru alone. The present report summarizes the main results of these investigations

  13. Encouraging entrepreneurship in university labs: Research activities, research outputs, and early doctorate careers.

    Directory of Open Access Journals (Sweden)

    Michael Roach

    Full Text Available This paper investigates how the encouragement of entrepreneurship within university research labs relates with research activities, research outputs, and early doctorate careers. Utilizing a panel survey of 6,840 science & engineering doctoral students at 39 R1 research universities, this study shows that entrepreneurship is widely encouraged across university research labs, ranging from 54% in biomedical engineering to 18% in particle physics, while only a small share of labs openly discourage entrepreneurship, from approximately 3% in engineering to approximately 12% in the life sciences. Within fields, there is no difference between labs that encourage entrepreneurship and those that do not with respect to basic research activity and the number of publications. At the same time, labs that encourage entrepreneurship are significantly more likely to report invention disclosures, particularly in engineering where such labs are 41% more likely to disclose inventions. With respect to career pathways, PhDs students in labs that encourage entrepreneurship do not differ from other PhDs in their interest in academic careers, but they are 87% more likely to be interested in careers in entrepreneurship and 44% more likely to work in a startup after graduation. These results persist even when accounting for individuals' pre-PhD interest in entrepreneurship and the encouragement of other non-academic industry careers.

  14. Activity report of the Neutrino Research Group. Year 2010

    International Nuclear Information System (INIS)

    2011-01-01

    For the last two decades, neutrino physics has been producing major discoveries including neutrino oscillations. These results gave clear confirmation that active neutrinos oscillate and therefore have mass with three different mass states. This is a very important result showing that the Minimal Standard Model is incomplete and requires an extension which is not yet known. The neutrino research field is very broad and active, at the frontier of today's particle physics. The Neutrino Research Group (GDR) was created in January 2005 with the aim of gathering CEA and CNRS research teams working on Neutrino Physics on experimental or theoretical level. This document is the 2010 activity report of the research group, six years after its creation. It presents the results of the 5 working groups: 1 - Determination of neutrino parameters; 2 - Physics beyond the standard model; 3 - Neutrinos in the universe; 4 - Accelerators, detection means, R and D and valorisation; 5 - Common tools to all working groups. The proposed neutrino physics road-map and the actual and future short-, medium- and long-term projects are presented in appendixes

  15. Narratives and Activity Theory as Reflective Tools in Action Research

    Science.gov (United States)

    Stuart, Kaz

    2012-01-01

    Narratives and activity theory are useful as socially constructed data collection tools that allow a researcher access to the social, cultural and historical meanings that research participants place on events in their lives. This case study shows how these tools were used to promote reflection within a cultural-historical activity theoretically…

  16. Finnish nurses' views on their research activities.

    Science.gov (United States)

    Kuuppelomäki, Merja; Tuomi, Jouni

    2003-07-01

    The purpose of the study reported here was to describe Finnish nurses' research and publication activities, as well as their views on the availability and utilization of research results in nursing practice. The data were collected using a structured questionnaire in which obstacles to the utilization of research results were measured with a previously developed instrument. A total of 400 nurses from community health centres, a central hospital and a central university hospital took part. Most of the nurses had carried out research on their own. Age, experience, training in research and development and other further training, as well as reading the nursing literature, were associated with doing research. Some of the reasons why the nurses had not carried out research were revealed. Publication of results was very rare. There were problems with the availability of research results. The most common obstacles to research utilization had to do with the presentation of results and the setting. In research utilization, respondents received most support from the ward manager and least support from doctors. If we want to encourage nurses to do research and increase the utilization of research results, greater effort should be invested in teaching research methodology, in introducing more flexible working hours and in developing other support systems.

  17. Oil and gas activities in the program energy research and development (PERD)

    International Nuclear Information System (INIS)

    Billette, N.; Marshall, S.-L.

    2002-01-01

    A broad range of non-nuclear energy research and development activities are covered under the umbrella of the Program of Energy Research and Development (PERD) managed by Natural Resources Canada. The research and development budget amounts to 52.5 million dollars annually, and is distributed across twelve federal departments and agencies. Horizontal coordinated research activities are taking place. Of this total budget, approximately 14 million dollars annually are spent to carry out oil and gas research and development activities by five federal departments and one agency. A results-based management for PERD was recently implemented by the Office of Energy Research and Development in an effort to improve the strategic management. Some of the efforts are directed toward research in the following general classification: upstream activities, offshore and frontier activities, and cross-cutting activities. Upgrading technologies and advanced separation technologies with the focus on oil sands bitumen represent the main issues addressed under the heading upstream activities. The major issues studied in the offshore and frontier activities are: basin assessment and geotechnics, wind-wave-current modelling, managing sea ice, ice-structure interactions, transportation safety, marine operations and ship design, management of offshore drilling and production waste, oil spills remediation and environmental impact assessment of offshore wastes and produced waters. Flaring, pipelines and soil and groundwater remediation are topics classified under the heading cross-cutting activities. The authors provided an overview of the activities and identified the future trends in PERD to meet the requirements of the various stakeholders and the Canadian population. 1 tab

  18. Oil and gas activities in the program energy research and development (PERD)

    Energy Technology Data Exchange (ETDEWEB)

    Billette, N.; Marshall, S.-L. [Natural Resources Canada, Ottawa, ON (Canada)

    2002-06-01

    A broad range of non-nuclear energy research and development activities are covered under the umbrella of the Program of Energy Research and Development (PERD) managed by Natural Resources Canada. The research and development budget amounts to 52.5 million dollars annually, and is distributed across twelve federal departments and agencies. Horizontal coordinated research activities are taking place. Of this total budget, approximately 14 million dollars annually are spent to carry out oil and gas research and development activities by five federal departments and one agency. A results-based management for PERD was recently implemented by the Office of Energy Research and Development in an effort to improve the strategic management. Some of the efforts are directed toward research in the following general classification: upstream activities, offshore and frontier activities, and cross-cutting activities. Upgrading technologies and advanced separation technologies with the focus on oil sands bitumen represent the main issues addressed under the heading upstream activities. The major issues studied in the offshore and frontier activities are: basin assessment and geotechnics, wind-wave-current modelling, managing sea ice, ice-structure interactions, transportation safety, marine operations and ship design, management of offshore drilling and production waste, oil spills remediation and environmental impact assessment of offshore wastes and produced waters. Flaring, pipelines and soil and groundwater remediation are topics classified under the heading cross-cutting activities. The authors provided an overview of the activities and identified the future trends in PERD to meet the requirements of the various stakeholders and the Canadian population. 1 tab.

  19. Preparing students for research activities in the context of ...

    African Journals Online (AJOL)

    Content of the innovative didactics of the technical university presented as a ... tasks, comprehensive, end-to-end research projects, interactive forms and methods; ... for research activities, program-target management system, resource model ...

  20. Vitamin D inadequacy is widespread in Tunisian active boys and is related to diet but not to adiposity or insulin resistance

    Directory of Open Access Journals (Sweden)

    Ikram Bezrati

    2016-04-01

    Full Text Available Background: Vitamin D inadequacy is widespread in children and adolescents worldwide. The present study was undertaken to assess the vitamin D status in active children living in a sunny climate and to identify the main determinants of the serum concentration of 25-hydroxyvitamin D (25-OHD. Methods: This cross-sectional study included 225 children aged 7–15 years practicing sports in a football academy. Anthropometric measures were performed to calculate body mass index (BMI, fat mass, and maturity status. A nutritional enquiry was performed including 3-day food records and food frequency questionnaire. Plasma 25-OHD and insulin were assessed by immunoenzymatic methods ensuring categorization of vitamin D status and calculation of insulin sensitivity/resistance indexes. A logistic regression model was applied to identify predictors for vitamin D inadequacy. Results: Vitamin D deficiency (25-OHD<12 µg/L was observed in 40.9% of children and insufficiency (12<25-OHD<20 µg/L was observed in 44% of children. In a multivariate analysis, vitamin D deficiency and insufficiency were associated with a lower dietary intake of vitamin D, proteins, milk, red meat, fish, and eggs. However, no significant relationship was observed with maturation status, adiposity, or insulin resistance. Conclusions: Tunisian children and adolescents are exposed to a high risk of vitamin D inadequacy despite living in a sunny climate. Circulating 25-OHD concentrations are related to the intake of vitamin D food sources but not to maturation status or body composition. Ensuring sufficient and safe sun exposure and adequate vitamin D intake may prevent vitamin D inadequacy in children from sunny environments.

  1. Using Random Numbers in Science Research Activities.

    Science.gov (United States)

    Schlenker, Richard M.; And Others

    1996-01-01

    Discusses the importance of science process skills and describes ways to select sets of random numbers for selection of subjects for a research study in an unbiased manner. Presents an activity appropriate for grades 5-12. (JRH)

  2. Nuclear power reactor safety research activities in CIAE

    International Nuclear Information System (INIS)

    Pu Shendi; Huang Yucai; Xu Hanming; Zhang Zhongyue

    1994-01-01

    The power reactor safety research activities in CIAE are briefly reviewed. The research work performed in 1980's and 1990's is mainly emphasised, which is closely related to the design, construction and licensing review of Qinshan Nuclear Power Plant and the safety review of Guangdong Nuclear Power Station. Major achievements in the area of thermohydraulics, nuclear fuel, probabilistic safety assessment and severe accident researches are summarized. The foreseeable research plan for the near future, relating to the design and construction of 600 MWe PWR NPP at Qinshan Site (phase II development) is outlined

  3. Prevention Research Matters-Communities Working to Improve Physical Activity

    Centers for Disease Control (CDC) Podcasts

    2018-02-15

    We know that children who are physically active every day are less likely to develop chronic diseases as adults, including obesity. Dr. Sandy Slater, a researcher with the University of Illinois, Chicago Prevention Research Center, discusses how a park improvement project in Chicago helped engage communities to improve areas for play and activity.  Created: 2/15/2018 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 2/15/2018.

  4. Summary reports of activities under visiting research program

    International Nuclear Information System (INIS)

    1984-01-01

    Technical Report of the Research Reactor Institute, Kyoto University, is published any time as a prompt report as occasion requires. In this report, the title, names of reporters and summary of each of 53 researches which were carried out under the visiting research program in the first half of 1983 are given. The titles are, for example, a mechanism for the anodic oxidation of GaAs, gamma-gamma perturbed angular correlation study of relaxation phenomena, the studies on the genesis of volcanic rocks by partition of trace elements, neutron activation analysis of geochemical standard rock samples, studies on the changes of elements in the fur of rats with various disease, neutron activation analysis on glacier ice strata and glaciegla lake sediments in Nepal Himalayas, low temperature irradiation effects on bcc metals, organ and its subcellular distribution of manganese ion in animals, structure analysis of orthorhombic BaTiO 3 by profile analysis method, regional distribution of Mn, Zn and Cu in human brain, neutron diffraction study of Mn-Ni alloy, structural change of KCoF 3 in the vicinity of the critical region, activation analysis of trace elements in tumor tissues (thyroid) and so on. (Kako, I.)

  5. Activity report on neutron scattering research. V. 1, 1994

    International Nuclear Information System (INIS)

    Fujii, Y.; Oohara, Y.

    1994-09-01

    In April, 1993, the Neutron Scattering Laboratory attached to the Institute for Solid State Physics, University of Tokyo, was newly established in Tokai, Ibaraki Prefecture, to promote nationwide users' programs for utilizing the university-owned neutron instruments installed at the JRR-3M reactor of Japan Atomic Energy Research Institute. This upgraded reactor (20 MW, the cold source is installed) has drastically expanded the number of users and research areas since 1990 when it became operational. Currently 8 and 3 out of 18 new spectrometers in total at the JRR-3M are owned by ISSP and Tohoku University, respectively, while the remaining 7 spectrometers belong to JAERI. In addition, 3 conventional spectrometers in the 30 years old JRR-2 reactor (10 MW) have also supported research activities. This is the first issue of 'Activity report on neutron scattering research', and it is to be published annually. In this report, the brief history of neutron scattering research, the users' programs, the committees, the neutron scattering instruments available at the JRR-3M and the JRR-2M, the activity reports on structures and excitation, magnetism, superconductors, liquid and glass, material science, polymers, biology and instrumentation, and publication list are reported. (K.I.)

  6. Summary reports of activities under visiting research program

    International Nuclear Information System (INIS)

    1985-01-01

    This report is published any time by summarizing in the form of an interim report the data required for research and experiment such as the results of the functional test on various experimental facilities, the test results of the products manufactured for trial, the state of radiation control and waste management, and the report of study meetings in the Research Reactor Institute, Kyoto University, the conspicuous results obtained halfway in research, new techniques, discussion on other papers and reports and others. In this report, the gists of 71 papers on the research activities under visiting research program performed in the second half of 1984 are collected, and the subject number, the title of research reporters, and the summary of report for each research are given. (Kako, I.)

  7. Transportation research activities in support of nuclear waste management programs

    International Nuclear Information System (INIS)

    Allen, G.C. Jr.; Cashwell, J.W.; Jefferson, R.M.

    1983-01-01

    Transportation Technology Center has been conducting a wide range of technical research activities to assure the ability to transport radioactive materials in a safe, reliable manner. These activities include tasks in basic, analysis methodology and system research areas. Recently, the requirements of defense waste shipments have served as a focal point for development tasks with the expectation that they would serve as a precursor for commercial activities. The passage of the Nuclear Waste Policy Act has placed additional responsibility on the Department of Energy for concerns involving the shipments of civilian materials. The development of additional research responsibilities is expected to proceed concurrently with the evolution of the transportation mission plan for civilian spent fuel and high-level wastes

  8. Report of Activity, 1996 - 1997. Vol. 3. General activities - Technical Research

    International Nuclear Information System (INIS)

    Pouthas, Joel; Hutin, Christiane; Niogret Mathias

    1999-01-01

    This is the third tome of the Report of Activity of IPN - Orsay on 1996-1997. It deals with general activities and technical research. Summary reports and short communications are grouped in the following sections: 1 - Accelerators with the sub-divisions 1.1 - R and D on superconducting RF cavities; 1.2 - SPIRAL Project; 1.3 - Contribution to the LHC Project; 1.4 - Tandem; 2 - Targets, Sources and Injectors; 3 - Detectors and related instrumentation; 4 - Electronics; 5 - Data processing; 6 - Radioprotection and medical applications

  9. Thorium research activities in Japan

    International Nuclear Information System (INIS)

    Sasa, Toshinobu

    2015-01-01

    The nuclear energy policy in Japan is based on the Uranium-Plutonium fuel cycle with Light Water Reactors (LWR) and Fast Breeder Reactors (FBR). After the accident at Fukushima-Daiichi Nuclear Power Plant, the Japanese government recognizes the importance to ensure the flexibility for future nuclear power generation and then, it was specified in the latest Japanese strategic energy plan. Two research groups related to thorium fuelled nuclear systems and fuel cycle was set up in the Atomic Energy Society of Japan in 2013. One is a 'Research Committee on Nuclear Applications of Molten Salt'. The committee was established to discuss the current molten-salt technology including molten-salt cooled reactor, molten-salt fuelled reactor, accelerator driven system, fusion reactor blankets and dry reprocessing processes. Throughout two years discussion, the committee summarizes a current state of the art and issues of molten-salt application systems. Committee also discussed the handling technologies for molten-salt reactors especially in China and United Kingdom, issues of molten-salt application to fusion reactor, dry reprocessing of spent nuclear fuel, and non-nuclear application of molten-salt. Term of the committee will be extended for further research activities

  10. 7 CFR 3400.21 - Scientific peer review for research activities.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Scientific peer review for research activities. 3400... STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE SPECIAL RESEARCH GRANTS PROGRAM Peer and Merit Review Arranged by Grantees § 3400.21 Scientific peer review for research...

  11. Widespread hematogenous metastases and Trousseau's syndrome in gastric adenocarcinoma

    Directory of Open Access Journals (Sweden)

    Santos Vitorino Modesto dos

    2001-01-01

    Full Text Available A case of widespread hematogenous metastases and Trousseau's syndrome is reported in a 40 year-old white housewife with gastric cancer, presenting subdural hematoma, ecchymoses, epistaxis, stomach and uterine bleeding. After undergoing hematoma drainage, she was unsuccessfully treated with platelets, red blood cells, plasma cryoprecipitate transfusions, and antibiotics. Necropsy disclosed gastric ring-signet adenocarcinoma invading the serous layer, with massive disseminated intravascular coagulation and systemic neoplastic embolism. Multiple old and recent hyaline (rich in fibrin and platelets microthrombi, and tumor emboli were observed in the bone marrow, meninges, liver, lungs, kidneys, lymph nodes, adrenals, thyroid, heart, pancreas, and ovaries (Krukenberg tumor.

  12. Achieving Widespread, Democratic Education in the United States Today: Dewey's Ideas Reconsidered

    Science.gov (United States)

    Meadows, Elizabeth; Blatchford, Katherine

    2009-01-01

    Excellent, democratic education that furthers each person's potential, success and happiness for her own and others' well-being is not yet widespread in the U.S. today. Dewey's The Public and Its Problems has much to say about the possibilities and challenges of achieving this goal. This paper examines Dewey's ideas about how a public for…

  13. Widespread Distribution of Trypodendron laeve in the Carpathian Mountains (Romania

    Directory of Open Access Journals (Sweden)

    Nicolai Olenici

    2018-05-01

    Full Text Available Trypodendron laeve Eggers, 1939 is a species of ambrosia beetle much less known than the other three Trypodendron species occurring in Europe. Its status (native or alien in Central Europe has been a subject of debate over the past two decades. In Romania, the species was discovered in 2008 and the aim of the research presented in this paper was to investigate its distribution in the Carpathians, mainly at high altitudes (>800 m, in tree stands with Norway spruce (Picea abies [L.] H. Karst. Panel intercept traps baited with synthetic pheromone for Trypodendron lineatum (Olivier, 1795 were used in the spring of 2015, at 31 locations. Adults of T. laeve were caught in 20 of them. Additional observations were made within some studies using similar baits and T. laeve specimens were caught in eight locations. T. laeve was always trapped together with T. lineatum, and at some locations also together with T. domesticum (Linnaeus, 1758 and T. signatum (Fabricius, 1787. In all traps, fewer specimens of T. laeve were caught compared to T. lineatum. The species has a widespread distribution in the mountain regions, within forests composed of native tree species and generally located far away from commercial routes. There, it occurs together with other native species of the same taxonomic genus. It seems to be more abundant at high altitudes, but overall its populations are less abundant than those of T. lineatum.

  14. The US federal framework for research on endocrine disrupters and an analysis of research programs supported during fiscal year 1996

    Science.gov (United States)

    Reiter, L.W.; DeRosa, C.; Kavlock, R.J.; Lucier, G.; Mac, M.J.; Melillo, J.; Melnick, R.L.; Sinks, T.; Walton, B.T.

    1998-01-01

    The potential health and ecological effects of endocrine disrupting chemicals has become a high visibility environmental issue. The 1990s have witnessed a growing concern, both on the part of the scientific community and the public, that environmental chemicals may be causing widespread effects in humans and in a variety of fish and wildlife species. This growing concern led the Committee on the Environment and Natural Resources (CENR) of the National Science and Technology Council to identify the endocrine disrupter issue as a major research initiative in early 1995 and subsequently establish an ad hoc Working Group on Endocrine Disrupters. The objectives of the working group are to 1) develop a planning framework for federal research related to human and ecological health effects of endocrine disrupting chemicals; 2) conduct an inventory of ongoing federal research programs; and 3) identify research gaps and develop a coordinated interagency plan to address priority research needs. This communication summarizes the activities of the federal government in defining a common framework for planning an endocrine disrupter research program and in assessing the status of the current effort. After developing the research framework and compiling an inventory of active research projects supported by the federal government in fiscal year 1996, the CENR working group evaluated the current federal effort by comparing the ongoing activities with the research needs identified in the framework. The analysis showed that the federal government supports considerable research on human health effects, ecological effects, and exposure assessment, with a predominance of activity occurring under human health effects. The analysis also indicates that studies on reproductive development and carcinogenesis are more prevalent than studies on neurotoxicity and immunotoxicity, that mammals (mostly laboratory animals) are the main species under study, and that chlorinated dibenzodioxins and

  15. Landslide research in the South Wales coalfield

    International Nuclear Information System (INIS)

    Bentley, S.P.; Siddle, H.J.

    1996-01-01

    The areal density of landslides in the coalfield of South Wales is one of the highest in the UK. During the past 100 years landsliding has had considerable impact, causing structural damage and loss of life. Most of the landslides were initiated under periglacial conditions but many became reactivated due to the activities of man, particularly, during the late 19th century when widespread urban and industrial development commenced in the Welsh valleys. A number of the area's larger landslides are first-time slides which occurred during the past 100 years. This paper sets out to chart the history of landslide research in the coalfield, which began through work by mining engineers. 47 refs., 6 figs., 2 tabs

  16. Research on neutron radiography in Research Reactor Institute, Kyoto University and activities related to it

    International Nuclear Information System (INIS)

    Fujine, Shigenori; Yoneda, Kenji

    1994-01-01

    The research on neutron radiography in Research Reactor Institute, Kyoto University was begun in 1974 using the E-2 experimental hole which was designed for neutron irradiation. It was reconstructed for the excellent performance as neutron radiography facility by fixing aluminum plugs, a collimator and so on. The research activities thereafter are briefly described. In 1989, the cold neutron facility was installed in the graphite thermal neutron facility, and the experiment on cold neutron radiography became feasible. The reactor in Kyoto University is of the thermal output of 5 MW, and is put to the joint utilization by universities and research institutes in whole Japan. The experimental items carried out so far are enumerated. At present, the main subjects of research are the development of the standard for establishing image evaluation method, the analysis of gas-liquid two-phase flow, the construction of the data base for the literatures and images of neutron radiography, the application of cold neutron radiography, the development of the imaging method using fast neutrons and so on. The thermal neutron radiography and the cold neutron radiography facilities of Kyoto University research reactor are described. The research and activities at Kyoto University research reactor and the investigation of problems are reported. (K.I.) 56 refs

  17. Qualitative Methods in Drug Utilization Research

    DEFF Research Database (Denmark)

    Almarsdóttir, Anna Birna; Bastholm Rahmner, Pia

    2016-01-01

    Qualitative research methods derive from the social sciences. Their use in drug utilization research is increasingly widespread, especially in understanding patient and prescriber perspectives. The main focus in qualitative research is exploration of a given phenomenon in order to get a wider...... understanding of why and how it appears. Qualitative research methods build on various theoretical underpinnings/schools of thought. The same validity and quality criteria cannot be used for both qualitative and quantitative methods....

  18. Japan FRI research activities on oil tank/spilled oil fire

    International Nuclear Information System (INIS)

    Koseki, Hiroshi

    1992-01-01

    Introduction of research activities on oil tank/spilled oil fire at FRI, Japan is done. FRI has a long history of studying oil tank and spilled oil fires. Many large oil fire tests were done. The purpose of these studies is different with research of response of oil spill, but the accumulation of this knowledge is useful for conducting elimination of spilled oil on the sea with burning. Therefore to do collaboration with fire science research groups, such as FRI is useful for future activities for response to oil spills

  19. Becker muscular dystrophy with widespread muscle hypertrophy and a non-sense mutation of exon 2.

    Science.gov (United States)

    Witting, N; Duno, M; Vissing, J

    2013-01-01

    Becker muscular dystrophy features progressive proximal weakness, wasting and often focal hypertrophy. We present a patient with pain and cramps from adolescence. Widespread muscle hypertrophy, preserved muscle strength and a 10-20-fold raised CPK were noted. Muscle biopsy was dystrophic, and Western blot showed a 95% reduction of dystrophin levels. Genetic analyses revealed a non-sense mutation in exon 2 of the dystrophin gene. This mutation is predicted to result in a Duchenne phenotype, but resulted in a mild Becker muscular dystrophy with widespread muscle hypertrophy. We suggest that this unusual phenotype is caused by translation re-initiation downstream from the mutation site. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. HIV Drug Resistance Surveillance in Honduras after a Decade of Widespread Antiretroviral Therapy.

    Science.gov (United States)

    Avila-Ríos, Santiago; García-Morales, Claudia; Tapia-Trejo, Daniela; Meza, Rita I; Nuñez, Sandra M; Parham, Leda; Flores, Norma A; Valladares, Diana; Pineda, Luisa M; Flores, Dixiana; Motiño, Roxana; Umanzor, Víctor; Carbajal, Candy; Murillo, Wendy; Lorenzana, Ivette; Palou, Elsa Y; Reyes-Terán, Gustavo

    2015-01-01

    We assessed HIV drug resistance (DR) in individuals failing ART (acquired DR, ADR) and in ART-naïve individuals (pre-ART DR, PDR) in Honduras, after 10 years of widespread availability of ART. 365 HIV-infected, ART-naïve, and 381 ART-experienced Honduran individuals were enrolled in 5 reference centres in Tegucigalpa, San Pedro Sula, La Ceiba, and Choluteca between April 2013 and April 2015. Plasma HIV protease-RT sequences were obtained. HIVDR was assessed using the WHO HIVDR mutation list and the Stanford algorithm. Recently infected (RI) individuals were identified using a multi-assay algorithm. PDR to any ARV drug was 11.5% (95% CI 8.4-15.2%). NNRTI PDR prevalence (8.2%) was higher than NRTI (2.2%) and PI (1.9%, p500 vs. Honduras remains at the intermediate level, after 10 years of widespread availability of ART. Evidence of ADR influencing the presence of PDR was observed by phylogenetic analyses and ADR/PDR mutation frequency correlations.

  1. Ethics of research for patients in pain.

    Science.gov (United States)

    Waisel, David B

    2017-04-01

    This review describes advances in rising and continuing ethical issues in research in patients in pain. Although some of the issues focus directly on pain research, such as research in neonatal pain management, others focus on widespread ethical issues that are relevant to pain research, such as scientific misconduct, deception, placebo use and genomics. Scientific misconduct is more widespread than realized and requires greater awareness of the markers of misconduct like irreproducibility. More education about what qualifies as misconduct, such as consent violations, plagiarism and inappropriate patient recruitment along with data falsification needs to be implemented. Wayward researchers may attend a rehabilitation conference to improve their practices. Studies in neonatal pain management do not require comparing an intervention with the inadequate analgesia of a placebo; comparing with a standard approach is sufficient. Deception of research patients may be acceptable under narrow circumstances. The legitimacy of using broad informed consent for biobanking and genomic studies are being challenged as changes to the Common Rule are being considered. Increasing complexity and the desire to further medical knowledge complicates research methods and informed consent. The ethical issues surrounding these and offshoot areas will continue to develop.

  2. Toward Active Living: "Comprehensive School Physical Activity Program" Research and Implications

    Science.gov (United States)

    Chen, Senlin; Gu, Xiangli

    2018-01-01

    Comprehensive school physical activity program (CSPAP) holds much promise as a solution for youth PA promotion, due to its strong theoretical and political support. In this article, we review the current research on CSPAP. Fifty-four published articles that met the inclusion criteria were identified and retrieved using direct library database…

  3. Artificial Sight Basic Research, Biomedical Engineering, and Clinical Advances

    CERN Document Server

    Humayun, Mark S; Chader, Gerald; Greenbaum, Elias

    2008-01-01

    Artificial sight is a frontier area of modern ophthalmology combining the multidisciplinary skills of surgical ophthalmology, biomedical engineering, biological physics, and psychophysical testing. Many scientific, engineering, and surgical challenges must be surmounted before widespread practical applications can be realized. The goal of Artificial Sight is to summarize the state-of-the-art research in this exciting area, and to describe some of the current approaches and initiatives that may help patients in a clinical setting. The Editors are active researchers in the fields of artificial sight, biomedical engineering and biological physics. They have received numerous professional awards and recognition for their work. The artificial sight team at the Doheny Eye Institute, led by Dr. Mark Humayun, is a world leader in this area of biomedical engineering and clinical research. Key Features Introduces and assesses the state of the art for a broad audience of biomedical engineers, biophysicists, and clinical...

  4. US Department of Energy reservior research activities Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Railsback, S.F.

    1991-01-01

    The US Department of Energy (DOE) does not directly manage large reservoirs, but DOE laboratories conduct research on reservoir monitoring, assessment, and enhancement under several activities. These activities include (1) studies and remedial actions for reservoirs affected by releases from DOE facilities, (2) industry- sponsored research on reservoir and stream fish, (3) climate change research, (4) hydropower impact assessment studies conducted for the Federal Energy Regulatory Commission (FERC), and (5) the DOE hydropower program. These activities fall under DOE's missions of providing support for environmentally sound energy technologies and managing the legacies of past waste disposal practices at DOE facilities. 9 refs

  5. [Clinical research activity of the French cancer cooperative network: Overview and perspectives].

    Science.gov (United States)

    Dubois, Claire; Morin, Franck; Moro-Sibilot, Denis; Langlais, Alexandra; Seitz, Jean-François; Girault, Cécile; Salles, Gilles; Haioun, Corinne; Deschaseaux, Pascal; Casassus, Philippe; Mathiot, Claire; Pujade-Lauraine, Éric; Votan, Bénédicte; Louvet, Christophe; Delpeut, Christine; Bardet, Étienne; Vintonenko, Nadejda; Hoang Xuan, Khê; Vo, Maryline; Michon, Jean; Milleron, Bernard

    The French Cancer Plan 2014-2019 stresses the importance of strengthening collaboration between all stakeholders involved in the fight against cancer, including cancer cooperative groups and intergroups. This survey aimed to describe the basics characteristics and clinical research activity among the Cancer Cooperative Groups (Groupes coopérateurs en oncologie). The second objective was to identify facilitators and barriers to their research activity. A questionnaire was sent to all the clinicians involved in 2014 as investigators in a clinical trial sponsored by one of the ten members of the Cancer Cooperative Groups network. The questions were related to their profile, research activity and the infrastructure existing within their healthcare center to support clinical research and related compliance activities. In total, 366 investigators responded to our survey. The academic clinical trials sponsored by the Cancer Cooperative Groups represented an important part of the research activity of the investigators in France in 2014. These academic groups contributed to the opening of many research sites throughout all regions in France. Factors associated with a higher participation of investigators (more than 10 patients enrolled in a trial over a year) include the existing support of healthcare professionals (more than 2 clinical research associate (CRA) OR=11.16 [3.82-32.6] compared to none) and the practice of their research activity in a University Hospital Center (CHU) rather than a Hospital Center (CH) (OR=2.15 [1.20-3.83]). This study highlighted factors that can strengthen investigator clinical research activities and subsequently improve patient access to evidence-based new cancer therapies in France. Copyright © 2017 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

  6. Current activities at the MIT Research Reactor

    International Nuclear Information System (INIS)

    Hu Linwen; Bernard, John A.; Harling, Otto K.; Kohse, Gordon E.; Ames, Michael; Olmez, Ilhan

    1998-01-01

    The MIT Research Reactor (MITR) is a MW nuclear research reactor that is owned and operated by the Massachusetts Institute of Technology to further its educational and research goals at both the undergraduate and graduate level. The reactor first achieved criticality in 1958. It was largely rebuilt in 1973/1974 by MIT staff and students, and its current license expires in August 1999. The current facility, which is designated as the MITR-H, uses a compact core with finned, aluminum-clad, plate-type fuel that is cooled and moderated by light water and reflected by heavy water. The reactor core can hold twenty-seven fuel elements. However, the normal configuration is twenty-four elements. A maximum of four fuel elements can be replaced with in-core experimental facilities. A unique feature of the MITR-II's design is that fixed absorber plates can be inserted in the upper half of the core. These cause the flux to peak in the lower half which benefits experimenters and also facilitates a fuel strategy that involves inversion of fuel elements midway through their life cycle. The MITR-II currently operates continuously for four weeks followed by shutdown of a few days for maintenance. This paper provides an overview of current activities at the MITR including preparations for re-licensing. The status of an on-going Phase-I clinical trial of boron neutron capture therapy for both glioblastoma multiforme and metastatic melanoma is described as well as the design of a fission converter facility for BNCT. Environmental research using neutron activation analysis is summarized as well as in-pile research focussed on LWR water chemistry and structural materials. (author)

  7. Tool to address green roof widespread implementation effect in flood characteristics for water management planning

    Directory of Open Access Journals (Sweden)

    R. Tassi

    2015-06-01

    Full Text Available In the last decades, new approaches were adopted to manage stormwater as close to its source as possible through technologies and devices that preserve and recreate natural landscape features. Green Roofs (GR are examples of these devices that are also incentivized by city's stormwater management plans. Several studies show that GR decreases on-site runoff from impervious surfaces, however, the analysis of the effect of widespread implementation of GR in the flood characteristics at the urban basin scale in subtropical areas are little discussed, mainly because of the absence of data. Thereby, this paper shows results related to the monitoring of an extensive modular GR under subtropical weather conditions, the development of a rainfall–runoff model based on the modified Curve Number (CN and SCS Triangular Unit Hydrograph (TUH methods and the analysis of large-scale impact of GR by modelling different basins. The model was calibrated against observed data and showed that GR absorbed almost all the smaller storms and reduced runoff even during the most intense rainfall. The overall CN was estimated in 83 (consistent with available literature with the shape of hydrographs well reproduced. Large-scale modelling (in basins ranging from 0.03 ha to several square kilometers showed that the widespread use of GRs reduced peak flows (volumes around 57% (48% at source and 38% (32% at the basin scale. Thus, this research validated a tool for the assessment of structural management measures (specifically GR to address changes in flood characteristics in the city's water management planning. From the application of this model it was concluded that even if the efficiency of GR decreases as the basin scale increase they still provide a good option to cope with urbanization impact.

  8. Co-ordinated research activities: Annual report and statistics for 2003

    International Nuclear Information System (INIS)

    2004-07-01

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These co-ordinated research activities are normally implemented through Co-ordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports several Doctoral CRPs. This new, optional type of CRP has been designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs are currently being carried out by the Human Health programme. Further information on the Agency's co-ordinated research activities, including current information on CRPs and programme areas supported, information on policies and procedures and the administration of the activities is contained in the Agency's website at http://www-crp.iaea.org. The co-ordinated research activities reported in this document are conducted in support of the following Agency programmes: Nuclear Power; Nuclear Fuel Cycle and Material Technologies; Analysis for Sustainable

  9. Co-ordinated research activities: Annual report and statistics for 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-15

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These co-ordinated research activities are normally implemented through Co-ordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports several Doctoral CRPs. This new, optional type of CRP has been designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs are currently being carried out by the Human Health programme. Further information on the Agency's co-ordinated research activities, including current information on CRPs and programme areas supported, information on policies and procedures and the administration of the activities is contained in the Agency's website at http://www-crp.iaea.org. The co-ordinated research activities reported in this document are conducted in support of the following Agency programmes: Nuclear Power; Nuclear Fuel Cycle and Material Technologies; Analysis for Sustainable

  10. IAEA Activities supporting education and training at research reactors

    International Nuclear Information System (INIS)

    Peld, N.D.; Ridikas, D.

    2013-01-01

    Full-text: Through the provision of neutrons for experiments and their historical association with universities, research reactors have played a prominent role in nuclear education and training of students, scientists and radiation workers. Today education and training remains the foremost application of research reactors, involving close to 160 facilities out of 246 operational. As part of its mandate to facilitate and expand the contribution of atomic energy to peace, health and prosperity throughout the world, the IAEA administers a number of activities intended to promote nuclear research and enable access to nuclear technology for peaceful purposes, one of which is the support of various education and training measures involving research reactors. In the last 5 years, education and training has formed one pillar for the creation of research reactor coalitions and networks to pool their resources and offer joint programmes, such as the on-going Group Fellowship Training Course. Conducted mainly through the Eastern European Research Reactor Initiative, this programme is a periodic sic week course for young scientists and engineers on nuclear techniques and administration jointly conducted at several member research reactor institutes. Organization of similar courses is under consideration in Latin America and the Asia-Pacific Region, also with support from the IAEA. Additionally, four research reactor institutes have begun offering practical education courses through virtual reactor experiments and operation known as the Internet Reactor Laboratory. Through little more than an internet connection and projection screens, university science departments can be connected regionally or bilaterally with the control room o a research reactor for various training activities. Finally, two publications are being prepared, namely Hands-On Training Courses Using Research Reactors and Accelerators, and Compendium on Education and training Based on Research Reactors. These

  11. Applied research and service activities at the University of Missouri Research Reactor Facility (MURR)

    International Nuclear Information System (INIS)

    Alger, D.M.

    1987-01-01

    The University Of Missouri operates MURR to provide an intense source of neutron and gamma radiation for research and applications by experimenters from its four campuses and by experimenters from other universities, government and industry. The 10 MW reactor, which has been operating an average of 155 hours per week for the past eight years, produces thermal neutron fluxes up to 6-7x10 14 n/cm 2 -s in the central flux trap and beamport source fluxes of up to 1.2x10 14 n/cm 2 -s. The mission of the reactor facility, to promote research, education and service, is the same as the overall mission of the university and therefore, applied research and service supported by industrial firms have been welcomed. The university recognized after a few years of reactor operation that in order to build utilization, it would be necessary to develop in-house research programs including people, equipment and activity so that potential users could more easily and quickly obtain the results needed. Nine research areas have been developed to create a broadly based program to support the level of activity needed to justify the cost of operating the facility. Applied research and service generate financial support for about one-half of the annual budget. The applied and service programs provide strong motivation for university/industry association in addition to the income generated. (author)

  12. RESEARCH ACTIVITIES AT THE US EPA'S GULF ECOLOGY DIVISION

    Science.gov (United States)

    The purpose of this talk was to present an overview of research activities at the US EPA's Office of Research and Development, Gulf Ecology Division located on Pensacola Beach, Florida. The talk was organized into three major sections. The first section covered my educational b...

  13. Research of the Nature of Leadership Activities

    Directory of Open Access Journals (Sweden)

    Andrea Jankurová

    2017-06-01

    Full Text Available Professional literature on leadership mostly states that a leader should be like (personality traits and describes different leadership styles and types. However, very little is known about what leaders do in their everyday practice, or how they do it. Leadership should be seen more widely and should be explored along the characteristics and style of leadership and how leaders are manifested externally through their work, which means to explore the nature of leadership work. The aim of the research project was to gain more knowledge about the activities undertaken by leaders to answer a simple, but yet not too clearly answered question: „What does a leader really do?“ This finding will help reveal important activities on which best leaders focus and determine which elements are really important for leadership. The research project was managed as a combination of interviews conducted with leaders, people on senior management positions along with a questionnaire survey.

  14. Research-based active-learning instruction in physics

    Science.gov (United States)

    Meltzer, David E.; Thornton, Ronald K.

    2013-04-01

    The development of research-based active-learning instructional methods in physics has significantly altered the landscape of U.S. physics education during the past 20 years. Based on a recent review [D.E. Meltzer and R.K. Thornton, Am. J. Phys. 80, 478 (2012)], we define these methods as those (1) explicitly based on research in the learning and teaching of physics, (2) that incorporate classroom and/or laboratory activities that require students to express their thinking through speaking, writing, or other actions that go beyond listening and the copying of notes, or execution of prescribed procedures, and (3) that have been tested repeatedly in actual classroom settings and have yielded objective evidence of improved student learning. We describe some key features common to methods in current use. These features focus on (a) recognizing and addressing students' physics ideas, and (b) guiding students to solve problems in realistic physical settings, in novel and diverse contexts, and to justify or explain the reasoning they have used.

  15. Research Article Special Issue

    African Journals Online (AJOL)

    pc

    2018-03-07

    Mar 7, 2018 ... INTRODUCTION ... the overview of the current research focus in personalized medicine ... widespread of the cloud computing data management and (iii) .... It is proposed that to maximize the usage of text mining, there is a need to develop .... emerging applications in text and data mining for biomedical ...

  16. Medical issues and research activity

    International Nuclear Information System (INIS)

    Orecchia, R.; Solcia, E.; Fossati, P.

    2006-01-01

    We want to report on the CNAO Centro Nazionale di Adroterapia Oncologica (National Centre for Oncological Hadrontherapy) Foundation activity aiming to create the clinical conditions that will enable CNAO to work in the most advantageous way. CNAO Foundation is taking care to inform the population, patients and medical community on the existence, potentiality and limits of hadrontherapy. To achieve this goal it has created a website that gives general information on hadrontherapy and a medical service that advises on specific clinical cases; it has moreover promoted seminars and courses for residents and specialists. Disease specific working groups have been created to define protocols on patients selection criteria, indications, dose and fractionation and to design clinical trials that will be carried out at CNAO. These protocols and trials are a working tool that will permit a more rational clinical activity. CNAO Foundation is promoting training of personnel that will work at CNAO and in the next few months physicians and physicists will be send abroad to learn the practical aspects of hadrontherapy in foreign facilities where hadrons are already in clinical use. CNAO Foundation is sponsoring research activity in the fields of precision patient positioning, organ motion management, in vivo dosimetry with in room positron emission tomography (PET) scan and radiobiology. These activities will help to take full advantage of the facility under construction and to better define the role of hadrontherapy in cancer care. (author)

  17. Applied research and development of neutron activation analysis

    International Nuclear Information System (INIS)

    Chung, Yong Sam; Moon, Jong Hwa; Kim, Sun Ha; Baek, Sung Ryel; Kim, Young Gi; Jung, Hwan Sung; Park, Kwang Won; Kang, Sang Hun; Lim, Jong Myoung

    2003-05-01

    The aims of this project are to establish the quality control system of Neutron Activation Analysis(NAA) due to increase of industrial needs for standard analytical method and to prepare and identify the standard operation procedure of NAA through practical testing for different analytical items. R and D implementations of analytical quality system using neutron irradiation facility and gamma-ray measurement system and automation of NAA facility in HANARO research reactor are as following ; 1) Establishment of NAA quality control system for the maintenance of best measurement capability and the promotion of utilization of HANARO research reactor 2) Improvement of analytical sensitivity for industrial applied technologies and establishment of certified standard procedures 3) Standardization and development of Prompt Gamma-ray Activation Analysis (PGAA) technology

  18. [Research activity in clinical biochemistry].

    Science.gov (United States)

    Jørgensen, Henrik L; Larsen, Birger; Ingwersen, Peter; Rehfeld, Jens F

    2008-09-01

    Quantitative bibliometric measurements of research activity are frequently used, e.g. for evaluating applicants for academic positions. The purpose of this investigation is to assess research activity within the medical speciality of Clinical Biochemistry by comparing it with a matched control group from other medical specialities in Denmark. A list of all physicians registered in Denmark (23,127 persons) was drawn from the database "Laeger.dk". Of these, 5,202 were generalists (not included) while 11,691 were from other specialities. Of the 126 specialists from Clinical Biochemistry, 57 fulfilled the inclusion criteria. Each of these 57 was matched according to medical title with two randomly chosen specialists from other specialities, totaling 114. Using Medline and the Web of Science, the number of publications and the number of citations were then ascertained. 25% of the 11,691 specialists held a PhD degree or doctoral degree, DMSci, (Clinical Biochemistry: 61%). The 171 specialists included in the study had 9,823 papers in Medline and 10,140 papers in the Web of Science. The number of Medline papers per specialist was 71 for Clinical Biochemistry compared to 51 for the control group. The number of citations per specialist was 1,844 for Clinical Biochemistry compared to 816 for the control group. The top ten H-indices (of which 8 were in Clinical Biochemistry) ranged from 30 to 69. Both the number of papers and the number of citations were higher for Clinical Biochemistry than for the control group. The difference was most pronounced among professors.

  19. Research activities for nuclear power plant aging promoted by PLEC, JAPEIC, Japan

    International Nuclear Information System (INIS)

    Maeda, Noriyoshi; Tajima, Kenichi

    2004-01-01

    In order to perform research activity for aging countermeasure of nuclear power plant effectively, Plant Life Engineering Center (PLEC) was established in Japan Power Engineering and Inspection Corporation (JAPEIC) in April 2000 sponsored by Ministry of International Trade and Industry (MITI, presently METI). Outlined activities of PLEC are as follows. Results of technical survey for research and development for aging phenomena have been summarized in a table (Research Map) categorizing them into ''inspection and monitoring'', ''evaluation method for aging'' and ''preventive maintenances and refurbishment''. Necessary research themes have been extracted from the Research Map consulting to experts of the specified research area and they are summarized into Medium and Long-term Research Perspective (Research Perspective), which contains prioritized research themes and outlined specification of each theme. Several new research themes proposed by various organizations and selected by PLEC as effective for the regulation activities are identified and proposed to be funded by METI every year. This paper also provides outlines and obtained results of aging related research projects currently conducted by JAPEIC sponsored by METI. (author)

  20. Observation-based assessment of functional ability in patients with chronic widespread pain: A cross-sectional study

    DEFF Research Database (Denmark)

    Amris, Kirstine; Wæhrens, Eva Elisabet Ejlersen; Jespersen, Anders

    2011-01-01

    Knowledge about functional ability, including activities of daily living (ADL), in patients with chronic widespread pain (CWP) and fibromyalgia (FMS) is largely based on self-report. The purpose of this study was to assess functional ability by using standardised, observation-based assessment...... of ADL performance and to examine the relationship between self-reported and observation-based measures of disability. A total of 257 women with CWP, 199 (77%) fulfilling the American College of Rheumatology tender point criteria for FMS, were evaluated with the Assessment of Motor and Process Skills...... (AMPS), an observation-based assessment providing linear measures of ADL motor and ADL process skill ability (unit: logits). A cutoff for effortless and independent ADL task performance is set at 2.0 for the motor scale and 1.0 for the process scale. A total of 248 (96.5%) had ability measures below...

  1. Chronic Widespread Back Pain is Distinct From Chronic Local Back Pain: Evidence From Quantitative Sensory Testing, Pain Drawings, and Psychometrics.

    Science.gov (United States)

    Gerhardt, Andreas; Eich, Wolfgang; Janke, Susanne; Leisner, Sabine; Treede, Rolf-Detlef; Tesarz, Jonas

    2016-07-01

    Whether chronic localized pain (CLP) and chronic widespread pain (CWP) have different mechanisms or to what extent they overlap in their pathophysiology is controversial. The study compared quantitative sensory testing profiles of nonspecific chronic back pain patients with CLP (n=48) and CWP (n=29) with and fibromyalgia syndrome (FMS) patients (n=90) and pain-free controls (n = 40). The quantitative sensory testing protocol of the "German-Research-Network-on-Neuropathic-Pain" was used to measure evoked pain on the painful area in the lower back and the pain-free hand (thermal and mechanical detection and pain thresholds, vibration threshold, pain sensitivity to sharp and blunt mechanical stimuli). Ongoing pain and psychometrics were captured with pain drawings and questionnaires. CLP patients did not differ from pain-free controls, except for lower pressure pain threshold (PPT) on the back. CWP and FMS patients showed lower heat pain threshold and higher wind-up ratio on the back and lower heat pain threshold and cold pain threshold on the hand. FMS showed lower PPT on back and hand, and higher comorbidity of anxiety and depression and more functional impairment than all other groups. Even after long duration CLP presents with a local hypersensitivity for PPT, suggesting a somatotopically specific sensitization of nociceptive processing. However, CWP patients show widespread ongoing pain and hyperalgesia for different stimuli that is generalized in space, suggesting the involvement of descending control systems, as also suggested for FMS patients. Because mechanisms in nonspecific chronic back pain with CLP and CWP differ, these patients should be distinguished in future research and allocated to different treatments.

  2. A bibliometric analysis of research updates and tendencies on steroid biotransformation

    Science.gov (United States)

    Song, Zhaoyu

    2018-03-01

    Steroid biotransformation, as a powerful tool for generation of steroid active pharmaceutical ingredients and key intermediates, has received widespread attention with increasing market demand for steroid-based drugs. In our study, a bibliometric analysis of steroid biotransformation was performed to trace the research updates and tendencies from 1993 to 2016, based on the Science Citation Index Expanded (SCIE) database. Results showed a notable growth trend in publication outputs. Although the USA was the most productive country between 1993 and 2016, developing nations, including China and India, contributed the prominent growth in recent years (2005–2016). Steroids was the leading journal in this field, and the research outputs had notably increased in the field of ‘Chemistry’, ‘Pharmacology and Pharmacy’ and ‘Biotechnology and Applied Microbiology’. Finally, research focused mainly on the efficient production of novel steroid active pharmaceutical ingredients and key intermediates through steroid biotransformation. Furthermore, cytochrome P450 involved in the side-chain oxidation of sterols has gradually become a hotspot issue in recent years.

  3. The potential behavioral and economic impacts of widespread HMG-CoA reductase inhibitor (statin) use.

    Science.gov (United States)

    Gendle, Mathew H

    2016-12-01

    Dyslipidemia is a common pathology throughout the industrialized world, and HMG-CoA reductase inhibitors (statins) are often administered to treat elevated lipid levels. Substantial concern has been raised regarding the aggressive clinical lowering of cholesterol, particularly in light of a growing body of research linking low circulating lipid levels with negative behavioral outcomes in both human samples and non-human primate models. In 2009, Goldstein and colleagues tentatively speculated that the greed, impulsiveness, and lack of foresight that lead to the worldwide economic collapse in 2007-2008 could have been caused (in part) by depressed population cholesterol levels resulting from the widespread use of statins by workers in the financial services industry. This paper reviews the literature that links low circulating lipid levels with neurobehavioral dysfunction, develops Goldstein and colleagues' initial speculation into a formal hypothesis, and proposes several specific studies that could rigorously empirically evaluate this hypothesis. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. READING HABITS IN DIGITAL ERA: A RESEARCH ON THE STUDENTS IN BORNEO UNIVERSITY

    Directory of Open Access Journals (Sweden)

    Firima Zona Tanjung

    2017-10-01

    Full Text Available This research aims to explore the current reading habits of university students. Moreover, it aims to determine the effects of widespread use of the internet and other digital resources in reading habits and to give some possible recommendation to improve students’ reading habits in the digital era. The research design was descriptive survey research. The instrument of the research was questionnaire, which is based on Akarsu and Dariyemez (2014 and Chauhan and Lal (2012. The participants of the research were 320 students studying in six majors in Faculty of Teachers Training and Education at Borneo University. They were selected through the cluster random sampling. The questionnaire involved six categories, namely demographic information, frequency of items read, contents of online reading, online activities, content first clicked when online, and techniques to develop reading habits. All research data was analyzed using SPSS Statistics 22 program.

  5. Air-quality implications of widespread adoption of cool roofs on ozone and particulate matter in southern California

    Science.gov (United States)

    Ban-Weiss, G. A.; Lee, S. M.; Katzenstein, A. S.; Carreras-Sospedra, M.; Zhang, X.; Farina, S.; Vahmani, P.; Fine, P.; Epstein, S. A.

    2017-12-01

    The installation of roofing materials with increased solar reflectance (i.e., "cool roofs") can mitigate the urban heat island effect and reduce energy use. In addition, meteorological changes, along with the possibility of enhanced UV reflection from these surfaces, can have complex impacts on ozone and PM2.5 concentrations. We aim to evaluate the air-quality impacts of widespread cool-roof installations prescribed by building energy efficiency standards within the heavily populated and polluted South Coast Air Basin (SoCAB) in Southern California. Development of a comprehensive rooftop area database and evaluation of spectral reflectance measurements of roofing materials allows us to predict potential future changes in solar and UV reflectance for simulations using the Weather Research Forecast and Community Multiscale Air Quality (CMAQ) models. Meteorological simulations indicate a decrease in daily maximum temperatures, daily maximum boundary layer heights, and ventilation coefficients throughout the SoCAB upon widespread installation of cool roofs. CMAQ simulations show significant increases in PM2.5 concentrations and policy-relevant design values. Changes in 8-h ozone concentrations depend on the potential change in UV reflectance, ranging from a decrease in population-weighted concentrations when UV reflectance remains unchanged to an increase when changes in UV reflectance are at an upper bound. However, 8-h policy-relevant ozone design values increase in all cases. Although the other benefits of cool roofs could outweigh small air-quality penalties, UV reflectance standards for cool roofing materials could mitigate these negative consequences. Results of this study motivate the careful consideration of future rooftop and pavement solar reflectance modification policies.

  6. Brazilian pediatric research groups, lines of research, and main areas of activity

    Directory of Open Access Journals (Sweden)

    Priscila H.A. Oliveira

    2015-05-01

    Conclusions: The pediatric research groups in Brazil have relevant scientific production, including works published in international publications, and are concentrated in regions with higher socioeconomic index. Most groups registered in CNPq started their activity in the last five years (46%, reflecting the recent growth of scientific production in this area.

  7. Widespread ecomorphological convergence in multiple fish families spanning the marine-freshwater interface.

    Science.gov (United States)

    Davis, Aaron M; Betancur-R, Ricardo

    2017-05-17

    The theoretical definition and quantification of convergence is an increasingly topical focus in evolutionary research, with particular growing interest on study scales spanning deep phylogenetic divergences and broad geographical areas. While much progress has recently been made in understanding the role of convergence in driving terrestrial (e.g. anole lizards) and aquatic (e.g. cichlids) radiations, little is known about its macroevolutionary effects across environmental gradients. This study uses a suite of recently developed comparative approaches integrating diverse aspects of morphology, dietary data, habitat affiliation and phylogeny to assess convergence across several well-known tropical-temperate fish families in the percomorph suborder Terapontoidei, a clade with considerable phenotypic and ecological diversity radiating in both marine and freshwater environments. We demonstrate significant widespread convergence across many lineages occupying equivalent trophic niches, particularly feeding habits such as herbivory and biting of attached prey off hard substrates. These include several examples of convergent morphotypes evolving independently in marine and freshwater clades, separated by deep evolutionary divergences (tens of millions of years). The Terapontoidei present a new example of the macroevolutionary dynamics of morphological and ecological coevolution in relation to habitat and trophic preferences, at a greater phylogenetic and habitat scale than most well-studied adaptive radiations. © 2017 The Author(s).

  8. Kosovo : Poverty assessment, Volume 1. Accelerating Inclusive Growth to Reduce Widespread Poverty

    OpenAIRE

    World Bank

    2007-01-01

    Poverty in Kosovo is widespread and has remained persistent in the first half of this decade. The evidence suggests that poverty is higher among those who live in families that are large, have many unemployed members, and have low education levels. The poor are also geographically concentrated in rural areas and a few regions. The main message of this report is that the slow and volatile g...

  9. Extracurricular research activities among senior medical students in Kuwait: experiences, attitudes, and barriers

    Directory of Open Access Journals (Sweden)

    Al-Halabi B

    2014-04-01

    Full Text Available Becher Al-Halabi,1 Yousef Marwan,2 Mohammad Hasan,3 Sulaiman Alkhadhari41Department of Surgery, Mubarak Al-Kabeer Hospital, Ministry of Health, Kuwait; 2Department of Orthopaedic Surgery, Al-Razi Hospital, Al-Sabah Medical Area, Ministry of Health, Kuwait; 3Department of Radiation Oncology, Kuwait Cancer Control Center, Al-Sabah Medical Area, Ministry of Health, Kuwait; 4Department of Psychiatry, Faculty of Medicine, Health Sciences Center, Kuwait University, KuwaitBackground: Research is the foundation of scientific advancement and improvement in quality of health care, which ensures the good health of the community. The aim of this study is to explore experiences, attitudes, and barriers of medical students in Kuwait University (KU in regards to extracurricular research.Methods: A questionnaire about extracurricular research activities (ie, any research activity that is not part of the required undergraduate curriculum, such as publishing a paper, research elective, etc was distributed to 175 senior medical students (years 6 and 7. Descriptive and chi-square analyses were used to analyze the responses, considering a P-value of <0.05 as the cut-off level for significance. The main outcome was defined as taking part in any of the extracurricular research activities.Results: Of the 150 participants (response rate = 85.7%, 26 (17.3%, 68 (45.3%, 52 (34.7%, and 17 (11.3% had published their required medical school research, presented abstracts in conferences, conducted extracurricular research, and completed a research elective/course, respectively; 99 (66.0% took part in any of these activities. Participants who read medical journals regularly (81; 54% reported higher participation in extracurricular research activities than those who did not read journals (P=0.003. Improving the availability of mentors for students' extracurricular research was ranked by the participants as the most important factor to improve their participation in

  10. Obtaining active parental consent for school-based research: a guide for researchers.

    Science.gov (United States)

    Wolfenden, Luke; Kypri, Kypros; Freund, Megan; Hodder, Rebecca

    2009-06-01

    Schools increasingly require researchers to obtain active parental consent for students to participate in health research. We sought to identify effective strategies for the recruitment of child research participants through schools. A search of Medline, PsycINFO, Educational Resources Information Center, ProQuest 5000 and the Cochrane Library electronic databases was conducted for the period 1988 to 2008. The review found evidence that the following strategies may be effective in enhancing participation rates: 1) promotion of the research to school principals, teachers, parents and students; 2) dissemination of study information using methods allowing direct contact with parents (i.e. telephone or face-to-face); 3) provision of incentives to teachers, students and at a class level; 4) making reminder contacts; and 5) having a member of the research team co-ordinate and closely monitor the recruitment process. Application of these strategies should reduce the risk of non-response and other biases that result from selective non-participation. Further randomised controlled trials of these and other strategies are required to strengthen the evidence base.

  11. Evidence for Widespread Associations between Neotropical Hymenopteran Insects and Actinobacteria

    Directory of Open Access Journals (Sweden)

    Bernal Matarrita-Carranza

    2017-10-01

    taxa and ranging from the American temperate to the Neotropical region. Our work thus provides important insights into the widespread distribution of Actinobacteria and hymenopteran insects associations, while also pointing at novel resources that could be targeted for the discovery of active natural products with great potential in medical and biotechnological applications.

  12. Evidence for Widespread Associations between Neotropical Hymenopteran Insects and Actinobacteria

    Science.gov (United States)

    Matarrita-Carranza, Bernal; Moreira-Soto, Rolando D.; Murillo-Cruz, Catalina; Mora, Marielos; Currie, Cameron R.; Pinto-Tomas, Adrián A.

    2017-01-01

    ranging from the American temperate to the Neotropical region. Our work thus provides important insights into the widespread distribution of Actinobacteria and hymenopteran insects associations, while also pointing at novel resources that could be targeted for the discovery of active natural products with great potential in medical and biotechnological applications. PMID:29089938

  13. Academic research as human activity: Occupational Therapy contributions for consumer participation

    Directory of Open Access Journals (Sweden)

    Tatiana Dimov

    2016-07-01

    Full Text Available The involvement of consumers in research is a recent trend in the world. Involving consumers in researches on health services, therapeutic approaches, effectiveness of support groups, mutual help groups, and even on medication is crucial for obtaining academic results that are representative of the group of consumers, and influence public policies that are effective and functional for consumers. This paper presents an analysis of how consumers can get involved in a research and what can be the role of an occupational therapist in such activity. When governed by the principles of autonomy, empowerment, and recovery, researches with consumer participation promote the principles of equality and recognition, allowing inclusion in the research process, and promoting the recognition of consumer knowledge. As an activity, research can be a motivator, mobilizing wills and desires. It can also be a possibility of leaving stagnation and making decisions. The occupational therapist can help this process. Occupational therapy focus on activities that are significant to the life of individuals. Participation in research becomes a focus for the therapeutic process to the extent that it presents itself as a demand for the client.

  14. Research activities at the TRIGA Mainz

    International Nuclear Information System (INIS)

    Eberhardt, K.; Trautmann, N.

    2002-01-01

    The TRIGA Mark II reactor of the Mainz University became first critical on August 3, 1965. It can be operated in the steady state mode with a maximum power of 100 kW and in the pulse mode with a peak power of 250 MW. The TRIGA Mainz is mainly used for neutron activation analysis, isotope production, basic research in nuclear chemistry and nuclear physics as well as for education and training

  15. Research activities of Academician Frantisek Behounek

    International Nuclear Information System (INIS)

    Spurny, Z.

    1979-01-01

    The biography and research and development activities are reviewed of the Czech physicists, Academician Frantisek Behounek. Discussed in more detail are Behounek's scientific contribution during the North Pole Expedition of the Italia airship commanded by U. Nobile, leading to the discovery of the so-called width effect of cosmic radiation and his scientific work in the post-World War II period in the dosimetry and protection of personnel handling ionizing radiation. (B.S.)

  16. MPD thruster research issues, activities, strategies

    Science.gov (United States)

    1991-01-01

    The following activities and plans in the MPD thruster development are summarized: (1) experimental and theoretical research (magnetic nozzles at present and high power levels, MPD thrusters with applied fields extending into the thrust chamber, and improved electrode performance); and (2) tools (MACH2 code for MPD and nozzle flow calculation, laser diagnostics and spectroscopy for non-intrusive measurements of flow conditions, and extension to higher power). National strategies are also outlined.

  17. Transcranial Magnetic Stimulation in the Treatment of Chronic Widespread Pain: A Randomized, Controlled Study

    Science.gov (United States)

    Avery, David H.; Zarkowski, Paul; Krashin, Daniel; Rho, Wang-ku; Wajdik, Chandra; Joesch, Jutta M.; Haynor, David R.; Buchwald, Dedra; Roy-Byrne, Peter

    2014-01-01

    Objective Our objective was to assess transcranial magnetic stimulation (TMS) in the treatment of chronic widespread pain (CWP). Methods Nineteen participants were randomized to two groups: one receiving active TMS (N=7) and another receiving sham stimulation (N=11) applied to the left dorsolateral prefrontal cortex. During sham stimulation, subjects heard a sound similar to the sound heard by those receiving the active treatment and received an active electrical stimulus to the scalp. The stimulation protocol consisted of 15 sessions completed within a 4-week period. Blind assessments were done at baseline and after each 5 sessions followed by blind assessments at 1 week, 1 month and 3 months after the last TMS sessions. The primary outcome variable was a pain measure, the Gracely Box Intensity Scale (BIRS). Results The percentage of subjects who guessed that they were receiving TMS was similar in the two groups. Both the TMS group and the sham group showed a statistically significant reduction in the BIRS scores from baseline during the acute phase of treatment and the follow-up phase. However, the TMS and sham groups did not differ in the change in the BIRS scores. Discussion Although some previous clinical studies and basic science studies of TMS in treating pain are promising, this study found no difference in the analgesic effect of TMS and sham stimulation. Future studies should utilize a sham condition that attempts to simulate the sound and sensation of the TMS stimulation. Stimulus location and other stimulus parameters should be explored in future studies. PMID:24755729

  18. Transcranial magnetic stimulation in the treatment of chronic widespread pain: a randomized controlled study.

    Science.gov (United States)

    Avery, David H; Zarkowski, Paul; Krashin, Daniel; Rho, Wang-Ku; Wajdik, Chandra; Joesch, Jutta M; Haynor, David R; Buchwald, Dedra; Roy-Byrne, Peter

    2015-03-01

    Our objective was to assess transcranial magnetic stimulation (TMS) in the treatment of chronic widespread pain. Nineteen participants were randomized into 2 groups: one group receiving active TMS (n = 7) and another group receiving sham stimulation (n = 11) applied to the left dorsolateral prefrontal cortex. During sham stimulation, subjects heard a sound similar to the sound heard by those receiving the active treatment and received an active electrical stimulus to the scalp. The stimulation protocol consisted of 15 sessions completed within a 4-week period. Blind assessments were done at baseline and after each 5 sessions followed by blind assessments at 1 week, 1 month, and 3 months after the last TMS sessions. The primary outcome variable was a pain measure, the Gracely Box Intensity Scale (BIRS). The percentage of subjects who guessed that they were receiving TMS was similar in the 2 groups. Both the TMS group and the sham group showed a statistically significant reduction in the BIRS scores from baseline during the acute phase of treatment and the follow-up phase. However, the TMS and sham groups did not differ in the change in the BIRS scores. Although some previous clinical studies and basic science studies of TMS in treating pain are promising, this study found no difference in the analgesic effect of TMS and sham stimulation. Future studies should use a sham condition that attempts to simulate the sound and sensation of the TMS stimulation. Stimulus location and other stimulus parameters should be explored in future studies.

  19. The Applied Behavior Analysis Research Paradigm and Single-Subject Designs in Adapted Physical Activity Research.

    Science.gov (United States)

    Haegele, Justin A; Hodge, Samuel Russell

    2015-10-01

    There are basic philosophical and paradigmatic assumptions that guide scholarly research endeavors, including the methods used and the types of questions asked. Through this article, kinesiology faculty and students with interests in adapted physical activity are encouraged to understand the basic assumptions of applied behavior analysis (ABA) methodology for conducting, analyzing, and presenting research of high quality in this paradigm. The purposes of this viewpoint paper are to present information fundamental to understanding the assumptions undergirding research methodology in ABA, describe key aspects of single-subject research designs, and discuss common research designs and data-analysis strategies used in single-subject studies.

  20. Bilateral widespread mechanical pain hypersensitivity as sign of central sensitization in patients with cluster headache.

    Science.gov (United States)

    Fernández-de-Las-Peñas, César; Ortega-Santiago, Ricardo; Cuadrado, María L; López-de-Silanes, Carlos; Pareja, Juan A

    2011-03-01

    To investigate bilateral widespread pressure pain hyperalgesia in deep tissues over symptomatic (trigemino-cervical) and nonsymptomatic (distant pain-free) regions in patients with cluster headache (CH). Central sensitization is claimed to play a relevant role in CH. No study has previously searched for widespread pressure hyperalgesia in deep tissues over both symptomatic (trigemino-cervical) and nonsymptomatic (distant pain-free) regions in patients with CH. Sixteen men (mean age: 43 ± 11 years) with CH in a remission phase and 16 matched controls were recruited. Pressure pain thresholds (PPTs) were bilaterally measured over the supra-orbital (V1), infra-orbital (V2), mental (V3), median (C5), radial (C6), and ulnar (C7) nerves, C5-C6 zygapophyseal joint, mastoid process, and tibialis anterior muscle by an assessor blinded to the subjects' condition. The results showed that PPT levels were significantly decreased bilaterally in patients with CH as compared with healthy controls (all sites, P < .001). A greater degree of sensitization over the mastoid process (P < .001) and a lower degree of sensitization over the tibialis anterior muscle (P < .01) was found. Our findings revealed bilateral widespread pressure pain hypersensitivity in patients with CH confirming the presence of central sensitization mechanisms in this headache condition. © 2010 American Headache Society.

  1. Widespread pollution of the South American atmosphere predates the industrial revolution by 240 years

    Science.gov (United States)

    Uglietti, Chiara; Gabrielli, Paolo; Cooke, Colin; Vallelonga, Paul; Thompson, Lonnie

    2015-04-01

    In the Southern Hemisphere, evidence for preindustrial atmospheric pollution is restricted to a few geological archives of low temporal resolution that record trace element deposition originating from past mining and metallurgical operations in South America. Therefore the timing and the spatial impact of these activities on the past atmosphere remain poorly constrained. Here we present an annually resolved ice-core record (793-1989 AD) from the high altitude drilling site of Quelccaya (Peru) that archives preindustrial and industrial variations in trace elements. During the pre-colonial period (i.e., pre-1532 AD), the deposition of trace elements was mainly dominated by the fallout of aeolian dust and of ash from occasional volcanic eruptions indicating that metallurgic production during the Inca Empire (1438-1532 AD) had a negligible impact on the South American atmosphere. In contrast, a widespread anthropogenic signal is evident after 1540 AD, which corresponds with the beginning of colonial mining and metallurgy in Peru and Bolivia, 240 years prior to the Industrial Revolution. This shift was due to a major technological transition for silver extraction in South America (1572 AD), from lead-based smelting to mercury amalgamation, which precipitated a massive increase in mining activities. However, deposition of toxic trace metals during the Colonial era was still several factors lower than 20th century pollution that was unprecedented over the entirety of human history.

  2. Widespread pollution of the South American atmosphere predates the industrial revolution by 240 y.

    Science.gov (United States)

    Uglietti, Chiara; Gabrielli, Paolo; Cooke, Colin A; Vallelonga, Paul; Thompson, Lonnie G

    2015-02-24

    In the Southern Hemisphere, evidence for preindustrial atmospheric pollution is restricted to a few geological archives of low temporal resolution that record trace element deposition originating from past mining and metallurgical operations in South America. Therefore, the timing and the spatial impact of these activities on the past atmosphere remain poorly constrained. Here we present an annually resolved ice core record (A.D. 793-1989) from the high-altitude drilling site of Quelccaya (Peru) that archives preindustrial and industrial variations in trace elements. During the precolonial period (i.e., pre-A.D. 1532), the deposition of trace elements was mainly dominated by the fallout of aeolian dust and of ash from occasional volcanic eruptions, indicating that metallurgic production during the Inca Empire (A.D. 1438-1532) had a negligible impact on the South American atmosphere. In contrast, a widespread anthropogenic signal is evident after around A.D. 1540, which corresponds with the beginning of colonial mining and metallurgy in Peru and Bolivia, ∼240 y before the Industrial Revolution. This shift was due to a major technological transition for silver extraction in South America (A.D. 1572), from lead-based smelting to mercury amalgamation, which precipitated a massive increase in mining activities. However, deposition of toxic trace metals during the Colonial era was still several factors lower than 20th century pollution that was unprecedented over the entirety of human history.

  3. Physical activity and pediatric multiple sclerosis: Developing a research agenda.

    Science.gov (United States)

    Yeh, E Ann; Kinnett-Hopkins, Dominique; Grover, Stephanie A; Motl, Robert W

    2015-11-01

    Three-quarters of children with multiple sclerosis (MS) experience fatigue or depression, and progressive neurocognitive decline may be seen as early as two years after MS diagnosis. Furthermore, a higher magnetic resonance imaging disease burden is seen in pediatric-onset MS compared with adult-onset MS. To date, limited knowledge exists regarding behavioral methods for managing symptoms and disease progression in pediatric MS. To that end, this paper builds an evidence-based argument for the possible symptomatic and disease-modifying effects of exercise and physical activity in pediatric MS. This will be accomplished through: (a) a review of pediatric MS and its consequences; (b) a brief overview of physical activity and its consequences in children and adults with MS; and (c) a selective review of research on the neurological benefits of physical activity in pediatric populations. This topical review concludes with a list of 10 questions to guide future research on physical activity and pediatric MS. The objective of this paper is the provision of a research interest, focus and agenda involving pediatric MS and its lifelong management though exercise and physical activity behavior. Such an agenda is critical as the effects and maintenance of physical activity and exercise track across the lifespan, particularly when developed in the early stages of life. © The Author(s), 2015.

  4. Strontium-89 in palliative treatment of widespread painful bone metastases: Response rate and duration

    International Nuclear Information System (INIS)

    Haddad, Peiman; Ghadiri, Farhad

    2005-01-01

    Full text: Intravenous injection of Strontium-89 (Sr-89) is an accepted palliative treatment for bone metastases. We evaluated the pain relief achieved with this radiopharmaceutical in patients with widespread painful bone metastases from prostate and breast cancers. Pain intensity on a 9-grade scale and use of narcotics was recorded before and after Sr-89 injection, and the ensuing palliative effect was divided into complete, partial and no response. The duration of response was also recorded. Thirty-five patients with widespread painful bone metastases were treated with Sr-89, of whom 22 had prostate and 13 breast cancers. Mean follow-up was 227 days, during which death was recorded for 32 patients. Fourteen patients (40%) had a complete response, 9 (26%) partial and 12 (34%) no response. In the 23 responding patients, mean duration of response was 6 months. In 17 patients the response was present until death. There was no significant relationship between pain response and patients' age or type of primary cancer. No side effects were recorded other than mild and temporary drop in white blood cell and platelet counts. Three patients with a complete response had a second injection of Sr-89 after progression of pain. One of these patients had a second partial response; the other 2 did not show a response to the second injection. The use of Sr-89 for treatment of widespread painful bone metastases from prostate and breast cancers in our department showed a 66% rate of response and a mean response duration of 6 months, with no significant side effects. (author)

  5. Widespread changes in white matter microstructure after a day of waking and sleep deprivation.

    Directory of Open Access Journals (Sweden)

    Torbjørn Elvsåshagen

    Full Text Available Elucidating the neurobiological effects of sleep and waking remains an important goal of the neurosciences. Recently, animal studies indicated that sleep is important for cell membrane and myelin maintenance in the brain and that these structures are particularly susceptible to insufficient sleep. Here, we tested the hypothesis that a day of waking and sleep deprivation would be associated with changes in diffusion tensor imaging (DTI indices of white matter microstructure sensitive to axonal membrane and myelin alterations.Twenty-one healthy adult males underwent DTI in the morning [7:30AM; time point (TP1], after 14 hours of waking (TP2, and then after another 9 hours of waking (TP3. Whole brain voxel-wise analysis was performed with tract based spatial statistics.A day of waking was associated with widespread increases in white matter fractional anisotropy, which were mainly driven by radial diffusivity reductions, and sleep deprivation was associated with widespread fractional anisotropy decreases, which were mainly explained by reductions in axial diffusivity. In addition, larger decreases in axial diffusivity after sleep deprivation were associated with greater sleepiness. All DTI changes remained significant after adjusting for hydration measures.This is the first DTI study of sleep deprivation in humans. Although previous studies have observed localized changes in DTI indices of cerebral microstructure over the course of a few hours, further studies are needed to confirm widespread DTI changes within hours of waking and to clarify whether such changes in white matter microstructure serve as neurobiological substrates of sleepiness.

  6. Neutron activation measurements in research reactor concrete shield

    International Nuclear Information System (INIS)

    Zagar, T.; Ravnik, M.; Bozic, M.

    2001-01-01

    The results of activation measurement inside TRIGA research reactor concrete shielding are given. Samples made of ordinary and barytes concrete together with gold and nickel foils were irradiated in the reactor body. Long-lived neutron-induced gamma-ray-emitting radioactive nuclides in the samples were measured with HPGe detector. The most active longlived radioactive nuclides in ordinary concrete samples were found to be 60 Co and 152 Eu and in barytes concrete samples 60 Co, 152 Eu and 133 Ba. Measured activity density of all nuclides was found to decrease almost linearly with depth in logarithmic scale.(author)

  7. THE WIDESPREAD OF Fe(III)-REDUCING BACTERIA IN NATURAL ECOSYSTEMS OF ECUADOR.

    Science.gov (United States)

    Tashyrev, O B; Govorukha, V M

    2015-01-01

    The widespread of Fe(III)-reducing microorganisms in natural ecosystems of Ecuador of La Favorita, Tungurahua volcano and Papallacta areas was experimentally proved. High efficiency of microbial precipitation of soluble iron compounds was also demonstrated. Obtained results indicate the potential ability of Fe(III)-reducing microorganisms to influence the formation of carbon and iron vector fluxes in ecosystems, as well as development of effective biotechnologies of water purification from iron compounds.

  8. Summary of activities of the Research Branch during 1983

    International Nuclear Information System (INIS)

    1985-11-01

    A summary of the activities performed during 1983 by the C.N.E.A.'s Research Branch in basic and applied research is given. The main activities and achievements obtained are shown in the following areas: 1) Physics Department: Tandar Project; Experimental Nuclear Physics; Theoretical Nuclear Physics; Solid State Physics; Technical Assistance and Engineering. 2) Reactor's Chemistry Department with its divisions: Radiation Chemistry; Chemical Control; Moderator and Coolant Physical Chemistry. 3) Radiobiology Department: Radiation Pathology; Genetics; Molecular Genetics; Somatic Effects; Radiomicrobiology; Irradiation and Dosimetry; Bioterium. 4) Prospective Department and Special Studies; Nuclear Fusion and Solar Energy and also, Biomathematics; Labelled Molecules and Radiochemistry. (M.E.L.) [es

  9. How about integration: the impact of online activities on store satisfaction and loyalty

    OpenAIRE

    Teerling, Marije L.

    2004-01-01

    Although there has been widespread support for the concept of integrating the Internet with other channels, relatively little empirical research has been conducted in this area. This paper examines the effects of integrated online activities on customer perceptions, i.e., satisfaction and loyalty, as well as customer behavior, i.e., purchases. As this study focuses on a nontransaction site, the purchases only take place in the store. Through structural equation modeling, we test a model that ...

  10. Bordeaux Gradignan Nuclear Research Centre - CENBG - 2009-2012 Activity report

    International Nuclear Information System (INIS)

    2013-01-01

    The Bordeaux Gradignan Nuclear Research Centre (CENBG) is a joint research unit of the CNRS/IN2P3 and the University Bordeaux 1 'Science and Technology'. The laboratory is composed of permanent researchers, permanent engineers and technicians and PhD students, post-docs and visitors. The scientific program covers a broad range of topics in nuclear physics, particle physics, Astro-particle physics as well as applications of subatomic physics to different multidisciplinary fields. The main research subjects are: exotic nuclei far from the valley of beta stability and rare radioactive decays; neutrino physics (type and mass of the neutrino) and double beta decay; high energy gamma ray astronomy; innovative approaches to nuclear power generation and transmutation of nuclear waste; laser induced nuclear excitations; the effects of various environmental exposures studied via macro, micro or nano-ion beams using the new platform AIFIRA; and finally theoretical studies of nuclear and hadronic matter. All these activities take place within strong national and international collaborations involving the academic world and enabling the selection and training of high-quality students and post-doctoral researchers. To promote dissemination in the regional and national network, within the technologies developed at the laboratory in the domain of characterization with beams of ions or neutrons, there exists a transfer unit ARCANE which works through contracts. This document is the 2009-2012 Activity report of CNBG, content: 1 - Research activities (Exotic nuclei; theoretical physics; laser nuclear excitations; Astro-particles; neutrino and low radioactivities; downstream of the fuel cycle and nuclear energy; radioactivity and environment; physics-biology interface; publications (journals, conferences and workshops); 2 - Skills and technical realisations (Electronics dept.; Instrumentation/detectors dept.; administration; Information and technology Dept.; Mechanics Dept.; Platform

  11. Bordeaux Gradignan Nuclear Research Centre - CENBG - 2013-2014 Activity report

    International Nuclear Information System (INIS)

    2015-01-01

    The Bordeaux Gradignan Nuclear Research Centre (CENBG) is a joint research unit of the CNRS/IN2P3 and the University Bordeaux 1 'Science and Technology'. The laboratory is composed of permanent researchers, permanent engineers and technicians and PhD students, post-docs and visitors. The scientific program covers a broad range of topics in nuclear physics, particle physics, Astro-particle physics as well as applications of subatomic physics to different multidisciplinary fields. The main research subjects are: exotic nuclei far from the valley of beta stability and rare radioactive decays; neutrino physics (type and mass of the neutrino) and double beta decay; high energy gamma ray astronomy; innovative approaches to nuclear power generation and transmutation of nuclear waste; laser induced nuclear excitations; the effects of various environmental exposures studied via macro, micro or nano-ion beams using the new platform AIFIRA; and finally theoretical studies of nuclear and hadronic matter. All these activities take place within strong national and international collaborations involving the academic world and enabling the selection and training of high-quality students and post-doctoral researchers. To promote dissemination in the regional and national network, within the technologies developed at the laboratory in the domain of characterization with beams of ions or neutrons, there exists a transfer unit ARCANE which works through contracts. This document is the 2013-2014 Activity report of CNBG, content: 1 - Research activities (Exotic nuclei; theoretical physics; laser nuclear excitations; Astro-particles; neutrino and low radioactivities; downstream of the fuel cycle and nuclear energy; radioactivity and environment; physics-biology interface; chemical imaging and speciation; publications (journals, conferences and workshops); 2 - Skills and technical realisations (Electronics dept.; Instrumentation/detectors dept.; administration; Information and technology

  12. Activity report on the utilization of research reactors. Japanese fiscal year, 2004

    International Nuclear Information System (INIS)

    2006-03-01

    During the fiscal year 2004, the Nuclear Science Research Institute research reactors carried out 7 cycles of joint use reactor operation at JRR-3 and 41 cycles at JRR-4. The research reactors are being utilized for various purposes including experimental studies such as neutron scattering, prompt gamma analysis, neutron radiography and medical irradiation (BNCT), and irradiation utilization such as neutron activation analysis of various samples, RI production, Irradiation Test of Reactor Materials and fission track, advanced Science Research. This volume contains 235 activity reports, which are categorized into the fields of neutron scattering (10 subcategories), neutron radiography, neutron activation analysis, RI Production, prompt gamma analysis, and others, submitted by the users in JAEA and from other organizations. (author)

  13. Passing the baton: Mentoring for adoption of active-learning pedagogies by research-active junior faculty.

    Science.gov (United States)

    Grimes, Catherine Leimkuhler; White, Harold B

    2015-01-01

    There are barriers to adoption of research-based teaching methods. Professional development workshops may inform faculty of these methods, but effective adoption often does not follow. In addition, newly-minted research-active faculty are often overwhelmed by the many new responsibilities (grant writing, group management, laboratory setup, teaching) that accompany the position and normally do not have the time to consider novel teaching approaches. This case study documents how over a three-year period, the responsibility for teaching a nontraditional "Introduction to Biochemistry" course in a problem-based learning format was successfully transferred from a senior faculty member nearing retirement (HBW) to a newly-hired research-active assistant professor (CLG). We describe our apprenticeship project involving modeling, scaffolding, fading, and coaching. We suggest that involving faculty in active-learning pedagogy early in their career with mentoring by senior faculty overcomes barriers to adopting these methods. This case describes a specific example from which potentially useful elements can be adopted and adapted wherever biochemistry is taught. © 2015 The International Union of Biochemistry and Molecular Biology.

  14. Publish literature on the research activities using the JMRT (II). Publication as JAERI research reports

    Energy Technology Data Exchange (ETDEWEB)

    Nagao, Yoshiharu; Ishii, Tadahiko; Niimi, Motoji; Fujiki, Kazuo; Takahashi, Hidetake (eds.) [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment

    2002-11-01

    The published reports on the research and development activities using the JMTR since 1971 to date have been surveyed by the search of literature database and questionnaire survey. This report compiles the title lists and abstracts of reports published by JAERI and survey the trend of the research and development in JAERI using the JMTR. (author)

  15. Published literature on the research activities using the JMRT (II). Publication as JAERI research reports

    International Nuclear Information System (INIS)

    Nagao, Yoshiharu; Ishii, Tadahiko; Niimi, Motoji; Fujiki, Kazuo; Takahashi, Hidetake

    2002-11-01

    The published reports on the research and development activities using the JMTR since 1971 to date have been surveyed by the search of literature database and questionnaire survey. This report compiles the title lists and abstracts of reports published by JAERI and survey the trend of the research and development in JAERI using the JMTR. (author)

  16. Research priorities for child and adolescent physical activity and sedentary behaviours

    DEFF Research Database (Denmark)

    Gillis, Lauren; Tomkinson, Grant; Olds, Timothy

    2013-01-01

    The quantity and quality of studies in child and adolescent physical activity and sedentary behaviour have rapidly increased, but research directions are often pursued in a reactive and uncoordinated manner.......The quantity and quality of studies in child and adolescent physical activity and sedentary behaviour have rapidly increased, but research directions are often pursued in a reactive and uncoordinated manner....

  17. Safety research activities on radioactive waste management in JNES

    International Nuclear Information System (INIS)

    Otsuka, Ichiro; Aoki, Hiroomi; Suko, Takeshi; Onishi, Yuko; Masuda, Yusuke; Kato, Masami

    2010-01-01

    Research activities in safety regulation of radioactive waste management are presented. Major activities are as follows. As for the geological disposal, major research areas are, developing 'safety indicators' to judge the adequacy of site investigation results presented by an implementer (NUMO), compiling basic requirements of safety design and safety assessment needed to make a safety review of the license application and developing an independent safety assessment methodology. In proceeding research, JNES, Japan Atomic Energy Agency (JAEA) and the National Institute of Advanced Industrial Science and Technology (AIST) signed an agreement of cooperative study on geological disposal in 2007. One of the ongoing joint studies under this agreement has been aimed at investigating regional-scale hydrogeological modeling using JAEA's Horonobe Underground Research Center. In the intermediate depth disposal, JNES conducted example analysis of reference facility and submitted the result to Nuclear Safety Commission of Japan (NSC). JNES is also listing issues to be addressed in the safety review of the license application and tries to make criteria of the review. Furthermore, JNES is developing analysis tool to evaluate long term safety of the facility and conducting an experiment to investigate long term behavior of engineered barrier system. In the near surface disposal of waste package, it must be confirmed by a regulatory inspector whether each package meets safety requirements. JNES continuously updates the confirmation methodology depending on new processing technologies. The clearance system was established in 2005. Two stages of regulatory involvement were adapted, 1) approval for measurement and judgment methods developed by the nuclear operator and 2) confirmation of measurement and judgment results based on approved methods. JNES is developing verification methodology for each stage. As for decommissioning, based on the regulatory needs and a research program

  18. Research and development activity in support of LCP

    International Nuclear Information System (INIS)

    Lubell, M.S.

    1979-01-01

    The research and development activity (RDAC) established in support of the Large Coil Program (LCP) at Oak Ridge National Laboratory (ORNL) is described. Some experimental results are presented and the importance of the RDAC to the magnet community is discussed

  19. Large space antenna communications systems: Integrated Langley Research Center/Jet Propulsion Laboratory development activities. 2: Langley Research Center activities

    Science.gov (United States)

    Cambell, T. G.; Bailey, M. C.; Cockrell, C. R.; Beck, F. B.

    1983-01-01

    The electromagnetic analysis activities at the Langley Research Center are resulting in efficient and accurate analytical methods for predicting both far- and near-field radiation characteristics of large offset multiple-beam multiple-aperture mesh reflector antennas. The utilization of aperture integration augmented with Geometrical Theory of Diffraction in analyzing the large reflector antenna system is emphasized.

  20. The Effects of Forest Therapy on Coping with Chronic Widespread Pain: Physiological and Psychological Differences between Participants in a Forest Therapy Program and a Control Group.

    Science.gov (United States)

    Han, Jin-Woo; Choi, Han; Jeon, Yo-Han; Yoon, Chong-Hyeon; Woo, Jong-Min; Kim, Won

    2016-02-24

    This study aimed to investigate the effects of a two-day forest therapy program on individuals with chronic widespread pain. Sixty one employees of a public organization providing building and facilities management services within the Seoul Metropolitan area participated in the study. Participants were assigned to an experimental group (n = 33) who participated in a forest therapy program or a control group (n = 28) on a non-random basis. Pre- and post-measures of heart rate variability (HRV), Natural Killer cell (NK cell) activity, self-reported pain using the visual analog scale (VAS), depression level using the Beck Depression Inventory (BDI), and health-related quality of life measures using the EuroQol Visual Analog Scale (EQ-VAS) were collected in both groups. The results showed that participants in the forest therapy group, as compared to the control group, showed physiological improvement as indicated by a significant increase in some measures of HRV and an increase in immune competence as indicated by NK cell activity. Participants in the forest therapy group also reported significant decreases in pain and depression, and a significant improvement in health-related quality of life. These results support the hypothesis that forest therapy is an effective intervention to relieve pain and associated psychological and physiological symptoms in individuals with chronic widespread pain.

  1. The IAEA collaborating centre for neutron activation based methodologies of research reactors

    International Nuclear Information System (INIS)

    Bode, P.

    2010-01-01

    The Reactor Institute Delft of the Delft University of Technology houses the Netherlands' only academic nuclear research reactor, with associated instrumentation and laboratories, for scientific education and research with ionizing radiation. The Institute's swimming pool type research reactor reached first criticality in 1963 and is currently operated at 2MW thermal powers on a 100 h/week basis. The reactor is equipped with neutron mirror guides serving ultra modern neutron beam physics instruments and with a very bright positron facility. Fully automated gamma-ray spectrometry systems are used by the laboratory for neutron activation analysis, providing large scale services under an ISO/IEC 17025:2005 compliant management system, being (since 1993) the first accredited laboratory of its kind in the world. Already for several years, this laboratory is sustainable by rendering these services to both the public and the private sector. The prime user of the Institute's fac ilities is the scientific Research Department of Radiation, Radionuclide and Reactors of the Faculty of Applied Sciences, housed inside the building. All reactor facilities are also made available for use by or for services to, external clients (industry, government, private sector, other (international research institutes and universities). The Reactor Institute Delft was inaugurated in May 2009 as a new lAEA Collaborating Centre for Neutron Activation Based Methodologies of Research Reactors. The collaboration involves education, research and development in (I) Production of reactor-produced, no-carrier added radioisotopes of high specific activity via neutron activation; (II) Neutron activation analysis with emphasis on automation as well as analysis of large samples, and radiotracer techniques and as a cross-cutting activity, (IIl) Quality assurance and management in research and application of research reactor based techniques and in research reactor operations. This c ollaboration will

  2. Trends in Research on Writing as a Learning Activity

    Directory of Open Access Journals (Sweden)

    Perry D. Klein

    2016-02-01

    Full Text Available This article discusses five trends in research on writing as a learning activity. Firstly, earlier decades were marked by conflicting views about the effects of writing on learning; in the past decade, the use of meta-analysis has shown that the effects of writing on learning are reliable, and that several variables mediate and moderate these effects. Secondly, in earlier decades, it was thought that text as a medium inherently elicited thinking and learning. Research during the past decade has indicated that writing to learn is a self-regulated activity, dependent on the goals and strategies of the writer. Thirdly, the Writing Across the Curriculum (WAC movement emphasized domain-general approaches to WTL. Much recent research is consistent with the Writing in the Disciplines (WID movement, incorporating genres that embody forms of reasoning specific to a given discipline. Fourthly, WTL as a classroom practice was always partially social, but the theoretical conceptualization of it was largely individual. During the past two decades, WTL has broadened to include theories and research that integrate social and psychological processes. Fifthly, WTL research has traditionally focused on epistemic learning in schools; more recently, it has been extended to include reflective learning in the professions and additional kinds of outcomes.

  3. Integrating research evidence and physical activity policy making-REPOPA project

    NARCIS (Netherlands)

    Aro, A.R.; Bertram, M.; Hamalainen, R.-M.; van de Goor, L.A.M.; Skovgaard, T.; Valente, A.; Castellani, T.; Chereches, R.; Edwards, N.

    2016-01-01

    Evidence shows that regular physical activity is enhanced by supporting environment. Studies are needed to integrate research evidence into health enhancing, cross-sector physical activity (HEPA) policy making. This article presents the rationale, study design, measurement procedures and the initial

  4. Electromechanically active polymer transducers: research in Europe

    Science.gov (United States)

    Carpi, Federico; Graz, Ingrid; Jager, Edwin; Ladegaard Skov, Anne; Vidal, Frédéric

    2013-10-01

    Smart materials and structures based on electromechanically active polymers (EAPs) represent a fast growing and stimulating field of research and development. EAPs are materials capable of changing dimensions and/or shape in response to suitable electrical stimuli. They are commonly classified in two major families: ionic EAPs (activated by an electrically induced transport of ions and/or solvent) and electronic EAPs (activated by electrostatic forces). These polymers show interesting properties, such as sizable active strains and/or stresses in response to electrical driving, high mechanical flexibility, low density, structural simplicity, ease of processing and scalability, no acoustic noise and, in most cases, low costs. Since many of these characteristics can also describe natural muscle tissues from an engineering standpoint, it is not surprising that EAP transducers are sometimes also referred to as 'muscle-like smart materials' or 'artificial muscles'. They are used not only to generate motion, but also to sense or harvest energy from it. In particular, EAP electromechanical transducers are studied for applications that can benefit from their 'biomimetic' characteristics, with possible usages from the micro- to the macro-scale, spanning several disciplines, such as mechatronics, robotics, automation, biotechnology and biomedical engineering, haptics, fluidics, optics and acoustics. Currently, the EAP field is just undergoing its initial transition from academic research into commercialization, with companies starting to invest in this technology and the first products appearing on the market. This focus issue is intentionally aimed at gathering contributions from the most influential European groups working in the EAP field. In fact, today Europe hosts the broadest EAP community worldwide. The rapid expansion of the EAP field in Europe, where it historically has strong roots, has stimulated the creation of the 'European Scientific Network for Artificial

  5. ETSON strategic orientations on research activities. ETSON research group activity

    Energy Technology Data Exchange (ETDEWEB)

    Van Dorseelaere, J.P.; Barrachin, M. [IRSN, Saint Paul les Durance (France). Centre de Cadarache; Millington, D. [Wood RSD, Warrington (United Kingdom); and others

    2018-01-15

    In 2011, ETSON published the ''Position Paper of the Technical Safety Organizations: Research Needs in Nuclear Safety for Gen 2 and Gen 3 NPPs''. This paper, published only a few months after the Fukushima-Daiichi severe accidents, presented the priorities for R and D on the main pending safety issues. It was produced by the ETSON Research Group (ERG) that has the mandate of identifying and prioritizing safety research needs, sharing information on research projects in which ETSON members are involved, defining and launching new research projects and disseminating knowledge among ETSON members. Six years after this publication, many R and D international projects finished in diverse frames, and other ones have started. In particular a lot of work was done (and is going on..) on the analysis of the Fukushima-Daiichi severe accidents. Meanwhile a roadmap on research on Gen. 2 and 3 nuclear power plants (NPP), including safety aspects, was produced by the NUGENIA association, followed by a more detailed document as ''NUGENIA global vision''. It was also demonstrated that the ETSON R and D priorities were consistent with the implementation of the 2014 Euratom Directive on safety of nuclear installations.

  6. Widespread rape does not directly appear to increase the overall HIV prevalence in conflict-affected countries: so now what?

    Directory of Open Access Journals (Sweden)

    Mills Edward

    2008-07-01

    Full Text Available Abstract Background Sub-Saharan Africa (SSA is severely affected by HIV/AIDS and conflict. Sexual violence as a weapon of war has been associated with concerns about heightened HIV incidence among women. Widespread rape by combatants has been documented in Burundi, Sierra Leone, Rwanda, Democratic Republic of Congo, Liberia, Sudan and Uganda. To examine the assertion that widespread rape may not directly increase HIV prevalence at the population level, we built a model to determine the potential impact of varying scenarios of widespread rape on HIV prevalence in the above seven African countries. Discussion Our findings show that even in the most extreme situations, where 15% of the female population was raped, where HIV prevalence among assailants was 8 times the country population prevalence, and where the HIV transmission rate was highest at 4 times the average high rate, widespread rape increased the absolute HIV prevalence of these countries by only 0.023%. These projections support the finding that widespread rape in conflict-affected countries in SSA has not incurred a major direct population-level change in HIV prevalence. However, this must not be interpreted to say that widespread rape does not pose serious problems to women's acquisition of HIV on an individual basis or in specific settings. Furthermore, direct and indirect consequences of sexual violence, such as physical and psychosocial trauma, unwanted pregnancies, and stigma and discrimination cannot be understated. Summary The conclusions of this article do not significantly change current practices in the field from an operational perspective. Proper care and treatment must be provided to every survivor of rape regardless of the epidemiological effects of HIV transmission at the population level. Sexual violence must be treated as a protection issue and not solely a reproductive health and psychosocial issue. It is worth publishing data and conclusions that could be

  7. THE RESEARCH ACTIVITY OF THE UNIVERSITY TEACHERS: DIRECTIONS, RESULTS, AND PROSPECTS. SOCIOLOGICAL CONTENT

    Directory of Open Access Journals (Sweden)

    I. A. Vasilyev

    2016-01-01

    Full Text Available The main purpose of an integrated monitoring research is the analysis of the main directions of research activity of faculty, staff and young scientists of the university.Methods. Scientific and theoretical analysis of publications on the researched topic are used as basic methods; sociological and diagnostic data collection methods; the method of statistical processing and classification of documentary and empirical data; the methods of content analysis and quantification of documentary and sociological information.Scientific novelty. The research is characterized by an integrated approach to the study of the problem: the basic provisions are analyzed; conclusions and recommendations of reports on research projects made by members of temporary research teams (or, university scientists and teaching staff. The classification (depending on the translation vectors results of dissertation works of graduate students, doctoral candidates is carried out in the course of the present study. Documentary information about the publication and presentation of scientific and pedagogical staff of the university is systematized; the report and information cards on the activities of innovative platforms are analyzed. The research team, with the direct participation of the author, after studying a few scientific publications on the subject, has developed an original method of complex research of the main directions of research activity of university scientists.Results. The presented research has allowed to note publication and innovative activity of the research and educational personnel, along with other its types, can act as the indicators characterizing the main directions of research activity both of higher education institution in general, and its concrete educational and scientific divisions. At the same, time the author emphasizes that efficiency of research process is caused not so much by quantitative as qualitative characteristics of concrete research

  8. Caribou response to human activity: research and management

    Directory of Open Access Journals (Sweden)

    Donald R. Miller

    2003-04-01

    Full Text Available This paper describes the need by researchers and managers of caribou (Rangifer tarandus to carefully assess the impact of their study methods on animals and results. An error made during a study of barren-ground caribou is described. Assumptions made during preparation of study methods need to be tested during collection of data. Study plans should include communication with, and respect for, residents who depend on the caribou resource. During field observations of caribou behavior, feeding habits, rutting activity or sex and age composition, closer is not better. During capture, handling and marking activities, shorter processing time is better. During aerial surveys, photography, sex and age determinations, higher is better. When interpreting data collected from marked caribou, and generally applying to the unmarked population, caution is advised. The merits and drawbacks of helicopter use to capture and mark caribou for research and management need to be discussed.

  9. A Call for Examining Replication and Bias in Special Education Research

    Science.gov (United States)

    Cook, Bryan G.

    2014-01-01

    Valid, scientific research is critical for ascertaining the effects of instructional techniques on learners with disabilities and for guiding effective special education practice and policy. Researchers in fields such as psychology and medicine have identified serious and widespread shortcomings in their research literatures related to replication…

  10. Widespread hypermetabolism in symptomatic and asymptomatic episodes in Kleine-Levin syndrome.

    Directory of Open Access Journals (Sweden)

    Yves Dauvilliers

    Full Text Available BACKGROUND: No reliable biomarkers are identified in KLS. However, few functional neuroimaging studies suggested hypoactivity in thalamic and hypothalamic regions during symptomatic episodes. Here, we investigated relative changes in regional brain metabolism in Kleine-Levin syndrome (KLS during symptomatic episodes and asymptomatic periods, as compared to healthy controls. METHODS: Four drug-free male patients with typical KLS and 15 healthy controls were included. 18-F-fluorodeoxy glucose positron emission tomography (PET was obtained in baseline condition in all participants, and during symptomatic episodes in KLS patients. All participants were asked to remain fully awake during the whole PET procedure. RESULTS: Between state-comparisons in KLS disclosed higher metabolism in paracentral, precentral, and postcentral areas, supplementary motor area, medial frontal gyrus, thalamus and putamen during symptomatic episodes, and decreased metabolism in occipital and temporal gyri. As compared to healthy control subjects, KLS patients in the asymptomatic phase consistently exhibited significant hypermetabolism in a wide cortical network including frontal and temporal cortices, posterior cingulate and precuneus, with no detected hypometabolism. In symptomatic KLS episodes, hypermetabolism was additionally found in orbital frontal and supplementary motor areas, insula and inferior parietal areas, and right caudate nucleus, and hypometabolism in the middle occipital gyrus and inferior parietal areas. CONCLUSION: Our results demonstrated significant hypermetabolism and few hypometabolism in specific but widespread brain regions in drug-free KLS patients at baseline and during symptomatic episodes, highlighting the behavioral state-dependent nature of changes in regional brain activity in KLS.

  11. CURRENT STATUS OF RESEARCH PROJECT ACTIVITIES IN MEDICAL UNIVERSITIES IN BULGARIA.

    Directory of Open Access Journals (Sweden)

    Svetoslav Garov

    2013-07-01

    Full Text Available Introduction: In Bulgaria there are five medical universities: in the cities of Sofia, Plovdiv, Varna, Pleven and Stara Zagora. Their main mission is training specialists in the fields of medicine and health care, increasing their qualification by means of postgraduate education and performing research activities. One of medical universities’ top priorities is encouraging research activities mainly aimed at preparation and implementation of research projects. Aim: The purpose of our study is to examine the current status of research project activities in Bulgarian medical universities.Material and methods: In order to define the science competitions related to Bulgarian medical universities we have applied a documentary and sociological approach. Results: Research projects that Bulgarian medical universities can apply for are divided into two groups – national and international. The most significant international projects are European ones since Bulgaria is an EU member state and this allows us to participate in such projects. Conclusion: Universities should strive for establishing even better conditions for encouraging application for research projects aimed at developing competent and experienced staff, even though the majority of them may not obtain approval for financing.The changes in the situation regarding Bulgarian science require the implementation and development of more research staff motivated to improve their knowledge and skills in the relevant dynamically changing competition and project field.

  12. High Energy Physics Division semiannual report of research activities, July 1, 1996 - December 31, 1996

    International Nuclear Information System (INIS)

    Norem, J.; Rezmer, R.; Wagner, R.

    1997-12-01

    This report is divided into the following areas: (1) experimental research program; (2) theoretical research program; (3) accelerator research and development; (4) divisional computing activities; (5) publications; (6) colloquia and conference talks; (7) high energy physics community activities; and (7) High Energy Physics Division research personnel. Summaries are given for individual research programs for activities (1), (2) and (3)

  13. Research activities by INS cyclotron facility

    International Nuclear Information System (INIS)

    1992-06-01

    Research activities made by the cyclotron facility and the related apparatuses at Institute for Nuclear Study (INS), University of Tokyo, have been reviewed in terms of the associated scientific publications. This publication list, which is to be read as a continuation of INS-Rep.-608 (October, 1986), includes experimental works on low-energy nuclear physics, accelerator technology, instrumental developments, radiation physics and other applications in interdisciplinary fields. The publications are classified into the following four categories. (A) : Internal reports published in INS. (B) : Publications in international scientific journals on experimental research works done by the cyclotron facility and the related apparatuses at INS. Those made by outside users are also included. (C) : Publications in international scientific journals on experimental low-energy nuclear physics, which have been done by the staff of INS Nuclear Physics Division using facilities outside INS. (D) : Contributions to international conferences. (author)

  14. Attitude Research in Science Education: Contemporary Models and Methods.

    Science.gov (United States)

    Crawley, Frank E.; Koballa, Thomas R., Jr.

    Social interaction and influence have been the subject of considerable research. Examining in great detail the factors involved in social influence has enabled social psychologists to understand better the effects of persuasion, propaganda, coercion, indoctrination, and brainwashing. Out of this research has come a widespread acceptance of the…

  15. Recent Research and Application Activities on Structural Health ...

    African Journals Online (AJOL)

    ... newly constructed bridges, (2) research and development activities on smart sensors such as optical fiber sensors and piezo-electric sensors, (3) structural damage detection methods using measured data, and (4) a test road project for pavement design verification and enhancement by the Korea Highway Corporation.

  16. Research activities for nuclear power plant aging promoted by PLEC, JAPEIC, Japan

    International Nuclear Information System (INIS)

    Maeda, N.; Tajima, K.

    2003-01-01

    In order to perform research activity for aging; countermeasure of nuclear power plant effectively, Plant Life Engineering Center (PLEC) was established in Japan Power Engineering and Inspection Corporation (JAPEIC) in April 2000 sponsored by Ministry of Economy, Trade and Industry (METI, called as MITI, at that time). Results of technical survey for research and development for aging phenomena have been summarized in a table (Research Map) categorizing them into 'inspection and monitoring', 'evaluation method for aging' and 'preventive maintenances and refurbishment'. Necessary research themes have been extracted from the Research Map consulting to experts of the specified research area. Medium and long-term research perspective (Research Perspective) has been established which contains prioritized research themes and outlined specification of each theme. Several new research themes proposed by various organizations and selected by PLEC as effective for the regulation activities of METI every year. There are about ten on-going research programs funded by METI. Their progress and performance are evaluated annually to improve their efficiency including their alteration, abolition and integration. This cycle of research is going to be attained successfully. Technology Advisory Committee composed of members from various field of nuclear power including prefectural and municipal governments supervises the PLEC activity to concentrate national wide potentials and to secure transparency, openness and neutrality. This paper also provides an outline of the aging related research projects currently conducted by JAPEIC under the auspices of METI. (author)

  17. Widespread osteolytic lesions of the long bones in basal cell nevus syndrome

    International Nuclear Information System (INIS)

    Blinder, G.; Barki, Y.; Bar-Ziv, J.; Pezt, M.

    1984-01-01

    Three members of a family, father, daughter, and son, with the basal cell nevus syndrome are presented. A very unusual manifestation of widespread cyst-like osteolytic lesions in all the tubular bones was observed in the father, together with osteoblastic spotty 'osteopoikilotic' lesions in the skull and the mandible of the same patient. Cyst-like osteolytic lesions have been described previously in this syndrome, mainly in the phalanges. We believe that such lesions can occur in any bone. (orig.)

  18. Mediation analysis of the relationship between institutional research activity and patient survival

    DEFF Research Database (Denmark)

    Rochon, Justine; du Bois, Andreas; Lange, Theis

    2014-01-01

    BACKGROUND: Recent studies have suggested that patients treated in research-active institutions have better outcomes than patients treated in research-inactive institutions. However, little attention has been paid to explaining such effects, probably because techniques for mediation analysis...... existing so far have not been applicable to survival data. METHODS: We investigated the underlying mechanisms using a recently developed method for mediation analysis of survival data. Our analysis of the effect of research activity on patient survival was based on 352 patients who had been diagnosed...... mediated through either optimal surgery or chemotherapy. Taken together, about 26% of the beneficial effect of research activity was mediated through the proposed pathways. CONCLUSIONS: Mediation analysis allows proceeding from the question "Does it work?" to the question "How does it work?" In particular...

  19. Activities report 1991-1992: Nuclear Research Center of Strasbourg

    International Nuclear Information System (INIS)

    1993-01-01

    This activities report of the Nuclear Research Centre of Strasbourg for the years 1991 and 1992, presents nine research axis: theoretical physics, mechanisms of reactions and nuclear structure, extreme forms of nuclei, exotic nuclei, hot and dense nuclear matter, ultra-relativistic heavy ions, physics of LEP (European Large Electron-Positron storage ring) at 'DELPHI', chemistry and physics of radiations, physics and applications of semi-conductors

  20. Accelerator and Fusion Research Division: Summary of activities, 1986

    International Nuclear Information System (INIS)

    1987-01-01

    This report contains a summary of activities at the Lawrence Berkeley Laboratory's Accelerator and Fusion Research Division for the year 1986. Topics and facilities investigated in individual papers are: 1-2 GeV Synchrotron Radiation Source, the Center for X-Ray Optics, Accelerator Operations, High-Energy Physics Technology, Heavy-Ion Fusion Accelerator Research and Magnetic Fusion Energy. Six individual papers have been indexed separately

  1. Status of UFD Campaign International Activities in Disposal Research

    Energy Technology Data Exchange (ETDEWEB)

    Birkholzer, Jens [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2012-09-01

    While the United States research program for geologic disposal of high-level radioactive waste over the past decades focused solely on an open tunnel emplacement in unsaturated densely fractured tuff, several international organizations have made significant progress in the characterization and performance evaluation of other disposal design options and host rock characteristics, most of which were very different from those studied in the U.S. As a result, areas of direct collaboration between the U.S. Department of Energy’s (DOE) and international geologic disposal programs were quite limited during that time. Recently, the decision by DOE to no longer pursue the geologic disposal of high-level radioactive waste and spent fuel at the Yucca Mountain site has shifted the nation’s focus to disposal design options and geologic environments similar to those being investigated by other nations. DOE started to recognize that close international collaboration is a beneficial and costeffective strategy for advancing disposal science and, in FY12, embarked on a comprehensive effort to identify international collaboration opportunities, to interact with international organizations and advance promising collaborations, and to plan/develop specific R&D activities in cooperation with international partners. This report describes the active collaboration opportunities available to U.S. researchers as a result of this effort, and presents specific cooperative research activities that have been recently initiated within DOE’s disposal research program. The focus in this report is on those opportunities that provide access to field data (and respective interpretation/modeling), and/or may allow participation in ongoing and planned field experiments.

  2. Diet, Lifestyle and Chronic Widespread Pain: Results from the 1958 British Birth Cohort Study

    Directory of Open Access Journals (Sweden)

    Elizabeth G VanDenKerkhof

    2011-01-01

    Full Text Available OBJECTIVES: To examine the relationship between diet and lifestyle, and chronic widespread pain (CWP. If persons with CWP have dietary and lifestyle habits consistent with an increased risk of cancer or cardiovascular disease, it may partially explain evidence in the literature suggesting an association between CWP and these diseases.

  3. Sacrococcygeal chordomas with wide-spread metastases: report of two cases and review of literature

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Hyun Suk; Shin, Young Ju; Joo, Mee; Kim, Byung Jik [College of Medicine, Inje Univ., Pusan (Korea, Republic of)

    1999-03-01

    Chordomas are rare tumors arising from the primitive notochord. The commonest affected segment is the sacrum and these chordomas frequently follow a progressive course with multiple recurrences and metastases and eventual death due to tumor. This report describes two cases of sacrococcygeal chordomas with widespread metastases treated by surgery and adjuvant radiation therapy.

  4. Sacrococcygeal chordomas with wide-spread metastases: report of two cases and review of literature

    International Nuclear Information System (INIS)

    Suh, Hyun Suk; Shin, Young Ju; Joo, Mee; Kim, Byung Jik

    1999-01-01

    Chordomas are rare tumors arising from the primitive notochord. The commonest affected segment is the sacrum and these chordomas frequently follow a progressive course with multiple recurrences and metastases and eventual death due to tumor. This report describes two cases of sacrococcygeal chordomas with widespread metastases treated by surgery and adjuvant radiation therapy

  5. Bilateral widespread mechanical pain sensitivity in carpal tunnel syndrome: evidence of central processing in unilateral neuropathy.

    Science.gov (United States)

    Fernández-de-las-Peñas, César; de la Llave-Rincón, Ana Isabel; Fernández-Carnero, Josué; Cuadrado, María Luz; Arendt-Nielsen, Lars; Pareja, Juan A

    2009-06-01

    The aim of this study was to investigate whether bilateral widespread pressure hypersensitivity exists in patients with unilateral carpal tunnel syndrome. A total of 20 females with carpal tunnel syndrome (aged 22-60 years), and 20 healthy matched females (aged 21-60 years old) were recruited. Pressure pain thresholds were assessed bilaterally over median, ulnar, and radial nerve trunks, the C5-C6 zygapophyseal joint, the carpal tunnel and the tibialis anterior muscle in a blinded design. The results showed that pressure pain threshold levels were significantly decreased bilaterally over the median, ulnar, and radial nerve trunks, the carpal tunnel, the C5-C6 zygapophyseal joint, and the tibialis anterior muscle in patients with unilateral carpal tunnel syndrome as compared to healthy controls (all, P < 0.001). Pressure pain threshold was negatively correlated to both hand pain intensity and duration of symptoms (all, P < 0.001). Our findings revealed bilateral widespread pressure hypersensitivity in subjects with carpal tunnel syndrome, which suggest that widespread central sensitization is involved in patients with unilateral carpal tunnel syndrome. The generalized decrease in pressure pain thresholds associated with pain intensity and duration of symptoms supports a role of the peripheral drive to initiate and maintain central sensitization. Nevertheless, both central and peripheral sensitization mechanisms are probably involved at the same time in carpal tunnel syndrome.

  6. The covert world of fish biofluorescence: a phylogenetically widespread and phenotypically variable phenomenon.

    Directory of Open Access Journals (Sweden)

    John S Sparks

    Full Text Available The discovery of fluorescent proteins has revolutionized experimental biology. Whereas the majority of fluorescent proteins have been identified from cnidarians, recently several fluorescent proteins have been isolated across the animal tree of life. Here we show that biofluorescence is not only phylogenetically widespread, but is also phenotypically variable across both cartilaginous and bony fishes, highlighting its evolutionary history and the possibility for discovery of numerous novel fluorescent proteins. Fish biofluorescence is especially common and morphologically variable in cryptically patterned coral-reef lineages. We identified 16 orders, 50 families, 105 genera, and more than 180 species of biofluorescent fishes. We have also reconstructed our current understanding of the phylogenetic distribution of biofluorescence for ray-finned fishes. The presence of yellow long-pass intraocular filters in many biofluorescent fish lineages and the substantive color vision capabilities of coral-reef fishes suggest that they are capable of detecting fluoresced light. We present species-specific emission patterns among closely related species, indicating that biofluorescence potentially functions in intraspecific communication and evidence that fluorescence can be used for camouflage. This research provides insight into the distribution, evolution, and phenotypic variability of biofluorescence in marine lineages and examines the role this variation may play.

  7. NHS Trusts' clinical research activity and overall CQC performance - Is there a correlation?

    Science.gov (United States)

    Jonker, L; Fisher, S J

    2015-11-01

    Since the late 2000's, the creation of the National Institute for Health Research (NIHR) has transformed clinical research activity in the United Kingdom. This study sought to establish if there is a link between clinical research activity and overall NHS Trust performance. Retrospective cohort study. Data for NHS Trust performance were obtained from public databases, namely the Care Quality Commission (CQC) 2013 risk rating for overall performance, and 2012-13 NIHR records for clinical research activity. Applying Spearman's rank analysis, none of the Trust categories showed a correlation with CQC risk rating: small hospitals, r = -0.062 (P = 0.76; n = 27); medium, r = -0.224 (P = 0.13; n = 47); large, r = -0.008 (P = 0.96; n = 57); academic, r = -0.18 (P = 0.41; n = 24). Similar results were observed when CQC risk rating was compared with the number of different clinical research studies conducted per Trust. The degree of NIHR National Portfolio clinical research activity is not significantly related to CQC risk rating, used as an indicator of overall NHS Trust performance. Other studies have previously shown that increased research activity correlates with improved mortality rates, one component of CQC risk rating scores. Alternative tools may have to be explored to evaluate the impact of clinical research on NHS Trusts and its patients. Copyright © 2015 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  8. Embedding a Recovery Orientation into Neuroscience Research: Involving People with a Lived Experience in Research Activity.

    Science.gov (United States)

    Stratford, Anthony; Brophy, Lisa; Castle, David; Harvey, Carol; Robertson, Joanne; Corlett, Philip; Davidson, Larry; Everall, Ian

    2016-03-01

    This paper highlights the importance and value of involving people with a lived experience of mental ill health and recovery in neuroscience research activity. In this era of recovery oriented service delivery, involving people with the lived experience of mental illness in neuroscience research extends beyond their participation as "subjects". The recovery paradigm reconceptualises people with the lived experience of mental ill health as experts by experience. To support this contribution, local policies and procedures, recovery-oriented training for neuroscience researchers, and dialogue about the practical applications of neuroscience research, are required.

  9. Education Research as Analytic Claims: The Case of Mathematics

    Science.gov (United States)

    Hyslop-Margison, Emery; Rogers, Matthew; Oladi, Soudeh

    2017-01-01

    Despite widespread calls for evidence-based research in education, this strategy has heretofore generated a surprisingly small return on the related financial investment. Some scholars have suggested that the situation follows from a mismatch between education as an assumed field of study and applied empirical research methods. This article's…

  10. Overview of remote technologies applied to research reactor fuel

    International Nuclear Information System (INIS)

    Oerdoegh, M.; Takats, F.

    1999-01-01

    This paper gives a brief overview of the remote technologies applied to research reactor fuels. Due to many reasons, the remote technology utilization to research reactor fuel is not so widespread as it is for power reactor fuels, however, the advantages of the application of such techniques are obvious. (author)

  11. Diurnal adjustment in ultraviolet sunscreen protection is widespread among higher plants.

    Science.gov (United States)

    Barnes, Paul W; Flint, Stephan D; Tobler, Mark A; Ryel, Ronald J

    2016-05-01

    The accumulation of ultraviolet (UV)-absorbing compounds (flavonoids and related phenylpropanoids) in the epidermis of higher plants reduces the penetration of solar UV radiation to underlying tissues and is a primary mechanism of acclimation to changing UV conditions resulting from ozone depletion and climate change. Previously we reported that several herbaceous plant species were capable of rapid, diurnal adjustments in epidermal UV transmittance (T UV), but how widespread this phenomenon is among plants has been unknown. In the present study, we tested the generality of this response by screening 37 species of various cultivated and wild plants growing in four locations spanning a gradient of ambient solar UV and climate (Hawaii, Utah, Idaho and Louisiana). Non-destructive measurements of adaxial T UV indicated that statistically significant midday decreases in T UV occurred in 49 % of the species tested, including both herbaceous and woody growth forms, and there was substantial interspecific variation in the magnitude of these changes. In general, plants in Louisiana exhibited larger diurnal changes in T UV than those in the other locations. Moreover, across all taxa, the magnitude of these changes was positively correlated with minimum daily air temperatures but not daily UV irradiances. Results indicate that diurnal changes in UV shielding are widespread among higher plants, vary both within and among species and tend to be greatest in herbaceous plants growing in warm environments. These findings suggest that plant species differ in their UV protection "strategies" though the functional and ecological significance of this variation in UV sunscreen protection remains unclear at present.

  12. Workshop on Direct Contact Heat Transfer at the Solar Energy Research Institute

    CERN Document Server

    Boehm, R

    1988-01-01

    to increase the use of direct contact processes, the National Science Foundation sup­ ported a workshop on direct contact heat transfer at the Solar Energy Research Insti­ tute in the summer of 1985. We served as organizers for this workshop, which em­ phasized an area of thermal engineering that, in our opinion, has great promise for the future, but has not yet reached the point of wide-spread commercial application. Hence, a summary of the state of knowledge at this point is timely. The workshop had a dual objective: 1. To summarize the current state of knowledge in such a form that industrial practi­ tioners can make use of the available information. 2. To indicate the research and development needed to advance the state-of-the-art, indicating not only what kind of research is needed, but also the industrial poten­ tial that could be realized if the information to be obtained through the proposed research activities were available.

  13. Security approaches in using tablet computers for primary data collection in clinical research.

    Science.gov (United States)

    Wilcox, Adam B; Gallagher, Kathleen; Bakken, Suzanne

    2013-01-01

    Next-generation tablets (iPads and Android tablets) may potentially improve the collection and management of clinical research data. The widespread adoption of tablets, coupled with decreased software and hardware costs, has led to increased consideration of tablets for primary research data collection. When using tablets for the Washington Heights/Inwood Infrastructure for Comparative Effectiveness Research (WICER) project, we found that the devices give rise to inherent security issues associated with the potential use of cloud-based data storage approaches. This paper identifies and describes major security considerations for primary data collection with tablets; proposes a set of architectural strategies for implementing data collection forms with tablet computers; and discusses the security, cost, and workflow of each strategy. The paper briefly reviews the strategies with respect to their implementation for three primary data collection activities for the WICER project.

  14. Transportation research activities in support of nuclear waste management programs

    International Nuclear Information System (INIS)

    Allen, G.C.; Luna, R.E.; Jefferson, R.M.; Wowak, W.E.

    1983-01-01

    The Transportation Technology Center has been conducting a wide range of technical and non-technical research activities to assure the ability to transport radioactive materials in a safe, reliable, and publicly acceptable manner. These activities include tasks in Information and Intergovernmental issues, Safety Assessment and Environmental Analysis and Technology Development. Until recently, the requirements of defense waste shipments have served as a focal point for development tasks with the expectation that they would serve as a precursor for commercial activities. The passage of the Nuclear Waste Policy Act has placed additional responsibility on DOE for concerns involving the shipments of civilian materials. The development of additional research responsibilities is expected to proceed concurrently with the evolution of the transportation mission plan for civilian spent fuel and high-level wastes

  15. Assessment of use of library resources on research activities of ...

    African Journals Online (AJOL)

    Library resources use contribute immensely to the research output of agricultural scientists and also play significant roles in supporting agricultural development but resources are inadequately provided. The main objective of the study was to assess the use of library resources on research activities of scientists in three ...

  16. Application of the Human Activity Assistive Technology model for occupational therapy research.

    Science.gov (United States)

    Giesbrecht, Ed

    2013-08-01

    Theoretical models provide a framework for describing practice and integrating evidence into systematic research. There are few models that relate specifically to the provision of assistive technology in occupational therapy practice. The Human Activity Assistive Technology model is an enduring example that has continued to develop by integrating a social model of disability, concepts from occupational therapy theory and principles of assistive technology adoption and abandonment. This study first describes the core concepts of the Human Activity Assistive Technology model and reviews its development over three successive published versions. A review of the research literature reflects application of the model to clinical practice, study design, outcome measure selection and interpretation of results, particularly among occupational therapists. An evaluative framework is used to critique the adequacy of the Human Activity Assistive Technology model for practice and research, exploring attributes of clarity, simplicity, generality, accessibility and importance. Finally, recommendations are proposed for continued development of the model and research applications. Most of the existing research literature employs the Human Activity Assistive Technology model for background and study design; there is emerging evidence to support the core concepts as predictive factors. Although the concepts are generally simple, clear and applicable to occupational therapy practice and research, evolving terminology and outcomes become more complex with the conflation of integrated theories. The development of the Human Activity Assistive Technology model offers enhanced access and application for occupational therapists, but poses challenges to clarity among concepts. Suggestions are made for further development and applications of the model. © 2013 Occupational Therapy Australia.

  17. Spintharus flavidus in the Caribbean-a 30 million year biogeographical history and radiation of a 'widespread species'.

    Science.gov (United States)

    Dziki, Austin; Binford, Greta J; Coddington, Jonathan A; Agnarsson, Ingi

    2015-01-01

    The Caribbean island biota is characterized by high levels of endemism, the result of an interplay between colonization opportunities on islands and effective oceanic barriers among them. A relatively small percentage of the biota is represented by 'widespread species,' presumably taxa for which oceanic barriers are ineffective. Few studies have explored in detail the genetic structure of widespread Caribbean taxa. The cobweb spider Spintharus flavidus Hentz, 1850 (Theridiidae) is one of two described Spintharus species and is unique in being widely distributed from northern N. America to Brazil and throughout the Caribbean. As a taxonomic hypothesis, Spintharus "flavidus" predicts maintenance of gene flow among Caribbean islands, a prediction that seems contradicted by known S. flavidus biology, which suggests limited dispersal ability. As part of an extensive survey of Caribbean arachnids (project CarBio), we conducted the first molecular phylogenetic analysis of S. flavidus with the primary goal of testing the 'widespread species' hypothesis. Our results, while limited to three molecular loci, reject the hypothesis of a single widespread species. Instead this lineage seems to represent a radiation with at least 16 species in the Caribbean region. Nearly all are short range endemics with several distinct mainland groups and others are single island endemics. While limited taxon sampling, with a single specimen from S. America, constrains what we can infer about the biogeographical history of the lineage, clear patterns still emerge. Consistent with limited overwater dispersal, we find evidence for a single colonization of the Caribbean about 30 million years ago, coinciding with the timing of the GAARLandia landbridge hypothesis. In sum, S. "flavidus" is not a single species capable of frequent overwater dispersal, but rather a 30 my old radiation of single island endemics that provides preliminary support for a complex and contested geological hypothesis.

  18. Repeated and Widespread Evolution of Bioluminescence in Marine Fishes.

    Directory of Open Access Journals (Sweden)

    Matthew P Davis

    Full Text Available Bioluminescence is primarily a marine phenomenon with 80% of metazoan bioluminescent genera occurring in the world's oceans. Here we show that bioluminescence has evolved repeatedly and is phylogenetically widespread across ray-finned fishes. We recover 27 independent evolutionary events of bioluminescence, all among marine fish lineages. This finding indicates that bioluminescence has evolved many more times than previously hypothesized across fishes and the tree of life. Our exploration of the macroevolutionary patterns of bioluminescent lineages indicates that the present day diversity of some inshore and deep-sea bioluminescent fish lineages that use bioluminescence for communication, feeding, and reproduction exhibit exceptional species richness given clade age. We show that exceptional species richness occurs particularly in deep-sea fishes with intrinsic bioluminescent systems and both shallow water and deep-sea lineages with luminescent systems used for communication.

  19. Bordeaux Gradignan Nuclear Research Centre - CENBG - 2003-2004 Activity report

    International Nuclear Information System (INIS)

    2005-01-01

    The Bordeaux Gradignan Nuclear Research Centre (CENBG) is a joint research unit of the CNRS/IN2P3 and the University Bordeaux 1 'Science and Technology'. The laboratory is composed of permanent researchers, permanent engineers and technicians and PhD students, post-docs and visitors. The scientific program covers a broad range of topics in nuclear physics, particle physics, Astro-particle physics as well as applications of subatomic physics to different multidisciplinary fields. The main research subjects are: exotic nuclei far from the valley of beta stability and rare radioactive decays; neutrino physics (type and mass of the neutrino) and double beta decay; high energy gamma ray astronomy; innovative approaches to nuclear power generation and transmutation of nuclear waste; laser induced nuclear excitations; the effects of various environmental exposures studied via macro, micro or nano-ion beams using the new platform AIFIRA; and finally theoretical studies of nuclear and hadronic matter. All these activities take place within strong national and international collaborations involving the academic world and enabling the selection and training of high-quality students and post-doctoral researchers. To promote dissemination in the regional and national network, within the technologies developed at the laboratory in the domain of characterization with beams of ions or neutrons, there exists a transfer unit ARCANE which works through contracts. This document is the 2003-2004 Activity report of CNBG, content: 1 - Foreword; 2 - Research activities (Astro-particle, downstream of the fuel cycle and nuclear energy; laser nuclear excitations; physics-biology interface; neutrino and low radioactivities; exotic nuclei; theoretical physics); 3 - Services; 4 - Platform and cell facilities; 5 - other actions; 6 - scientific production; 7 - personnel

  20. Research Recommendations for Selected IARC-Classified Agents

    DEFF Research Database (Denmark)

    Ward, Elizabeth M; Schulte, Paul A; Straif, Kurt

    2010-01-01

    OBJECTIVES: There are some common occupational agents and exposure circumstances where evidence of carcinogenicity is substantial but not yet conclusive for humans. The objectives are to identify research gaps and needs for twenty agents prioritized for review based on evidence of widespread huma...

  1. Institute of Nuclear Physics, mission and scientific research activities

    International Nuclear Information System (INIS)

    Zoto, J.; Zaganjori, S.

    2004-01-01

    The Institute of Nuclear Physics (INP) was established in 1971 as a scientific research institution with main goal basic scientific knowledge transmission and transfer the new methods and technologies of nuclear physics to the different economy fields. The organizational structure and main research areas of the Institute are described. The effects of the long transition period of the Albanian society and economy on the Institution activity are also presented

  2. Widespread reductions of white matter integrity in patients with long-term remission of Cushing's disease

    Directory of Open Access Journals (Sweden)

    Steven J.A. van der Werff

    2014-01-01

    Conclusion: Patients with a history of endogenous hypercortisolism in present remission show widespread changes of white matter integrity in the brain, with abnormalities in the integrity of the uncinate fasciculus being related to the severity of depressive symptoms, suggesting persistent structural effects of hypercortisolism.

  3. Research reactor operations for neutron activation analysis

    International Nuclear Information System (INIS)

    Tv'ehlov, Yu.

    2002-01-01

    The IAEA Special Manual devoted to quality control during neutron activation analysis (NAA) on research and test reactors is discussed. Three parts of the publication involve presentation of common rules for performance of NAA, quantitative and qualitative analyses, statistic and systematic errors, safety regulations and radioactive waste management. Besides, the publication contains practical manual for the performance of NAA, and examples of different NAA regulating registration forms are presented [ru

  4. Activity report on the utilization of research reactors. Japanese fiscal year, 2002

    International Nuclear Information System (INIS)

    2004-08-01

    During the fiscal year 2002, the Tokai Research Establishment research reactors carried out 7 cycles of joint use reactor operation at JRR-3 and 39 cycles at JRR-4. The research reactors are being utilized for various purposes including experimental studies such as neutron scattering, prompt gamma analysis, neutron radiography and medical irradiation (BNCT), and irradiation utilization such as neutron activation analysis of various samples, Irradiation Test of Reactor Materials and fission track. This volume contains 279 activity reports, which are categorized into the fields of neutron scattering (9 subcategories), neutron radiography, neutron activation analysis, reactor materials, prompt gamma analysis, and others, submitted by the users in JAERI and from other organizations. (author)

  5. Activity report on the utilization of research reactors. Japanese fiscal year, 2003

    International Nuclear Information System (INIS)

    2005-09-01

    During the fiscal year 2003, the Tokai Research Establishment research reactors carried out 8 cycles of joint use reactor operation at JRR-3 and 42 cycles at JRR-4. The research reactors are being utilized for various purposes including experimental studies such as neutron scattering, prompt gamma analysis, neutron radiography and medical irradiation (BNCT), and irradiation utilization such as neutron activation analysis of various samples, Irradiation Test of Reactor Materials and fission track. This volume contains 246 activity reports, which are categorized into the fields of neutron scattering (9 subcategories), neutron radiography, neutron activation analysis, reactor materials, prompt analysis, and others, submitted by the users in JAERI and from other organizations. (author)

  6. The 1988 activity report of the Nuclear Research Center of Strasbourg

    International Nuclear Information System (INIS)

    1989-01-01

    The 1988 activity report of Nuclear Research Center of Strasbourg (France) is presented. 1988 is characterized by significant technical development activities in the field of heavy ion collisions. Several aspects involving the Vivitron system development and objectives are underlined. The main research fields are those on high angular momentum and superplasticity, layer model and nucleon transfer, nuclei far from steady state, scattering model and fusion cross sections. The research programs of the Nuclear Physics, High Energies, Chemistry and Radiation Physics Divisions are presented. Concerning technology transfer, the investigations on accelerators and dosimetry are included. International cooperation main aspects, papers, congress communications and conferences are reported [fr

  7. Scientific and technological activity in the National Institute of Nuclear Research

    International Nuclear Information System (INIS)

    Escobar A, L.; Monroy G, F.; Morales R, P.; Romero H, S.

    2008-01-01

    The present book was published on the occasion of the 50 years of the existence of the Institute, from its creation in 1956 like National Commission of Nuclear Energy to 1979 that arises like National Institute of Nuclear Research. The objective of this publication is the one to leave a writing testimony of all the activities that are realized in the National Institute of Nuclear Research and an accessible language within the diverse subjects boarded. Referring subjects to the activities of nuclear physics, radiochemistry, research and development of materials, dosimetry, plasma physics, production of radiopharmaceuticals, tissue sterilization by radiation, food irradiation and other included. (Author)

  8. A cross sectional observational study of research activity of allied health teams: is there a link with self-reported success, motivators and barriers to undertaking research?

    Science.gov (United States)

    Wenke, Rachel J; Mickan, Sharon; Bisset, Leanne

    2017-02-06

    Team-based approaches to research capacity building (RCB) may be an efficient means to promote allied health research participation and activity. In order to tailor such interventions, a clearer understanding of current patterns of research participation within allied health teams is needed. Different self-report measures exist which evaluate a team's research capacity and participation, as well as associated barriers and motivators. However, it remains unclear how such measures are associated with a team's actual research activity (e.g., journal publications, funding received). In response, this observational study aimed to identify the research activity, self-reported success, and motivations and barriers to undertaking research of eight allied health professional (AHP) teams and to explore whether any relationships exist between the self-reported measures and actual research activity within each team. A total of 95 AHPs from eight teams completed the research capacity and culture survey to evaluate team success, barriers and motivators to undertaking research, and an audit of research activity from January 2013 to August 2014 was undertaken within each team. Kendell's correlation coefficients were used to determine the association between research activity (i.e., number of journal publications, ethically approved projects and funding received) and the self-reported measures. Seven out of eight teams rated their teams as having average success in research and demonstrated some form of research activity including at least two ethically approved projects. Research activity varied between teams, with funding received ranging from $0 to over $100,000, and half the teams not producing any journal publications. Team motivators demonstrated a stronger association with research activity compared to barriers, with the motivator "enhancing team credibility" being significantly associated with funding received. No significant association between self-reported research

  9. Activity report on the utilization of research reactors. Japanese Fiscal Year, 1998

    Energy Technology Data Exchange (ETDEWEB)

    Toyoda, Masayuki; Koyama, Yoshimi [eds.; Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2000-03-01

    This is the second issue of the activity report on the utilization of research reactors in the fields of neutron beam experiments, neutron activation analysis, radioisotope production, etc., performed during Japanese Fiscal Year 1998 (April 1, 1998 - March 31, 1999). All reports in this volume were described by users from JAERI and also users from the other organizations, i.e., universities, national research institutes and private companies, who have utilized our research reactor utilization facilities for the purpose of the above studies. (author)

  10. Activity report on the utilization of research reactors. Japanese Fiscal Year, 1999

    International Nuclear Information System (INIS)

    Toyoda, Masayuki

    2001-03-01

    This is the second issue of the activity report on the utilization of research reactors in the fields of neutron beam experiments, neutron activation analysis, radioisotope production, etc., performed during Japanese Fiscal Year 1999 (April 1, 1999 - March 31, 2000). All reports in this volume were described by users from JAERI and also users from the other organizations, i.e., universities, national research institutes and private companies, who have utilized our research reactor utilization facilities for the purpose of the above studies. (author)

  11. Research

    African Journals Online (AJOL)

    raoul

    2012-04-16

    Apr 16, 2012 ... We chose to include male students in our study because previous studies have shown widespread lack of knowledge of the disease .... masculinity. ... The last few years have seen widespread use of internet social media.

  12. Scaffolding Assignments and Activities for Undergraduate Research Methods

    Science.gov (United States)

    Fisher, Sarah; Justwan, Florian

    2018-01-01

    This article details assignments and lessons created for and tested in research methods courses at two different universities, a large state school and a small liberal arts college. Each assignment or activity utilized scaffolding. Students were asked to push beyond their comfort zone while utilizing concrete and/or creative examples,…

  13. Reactor safety research. The CEC contribution

    International Nuclear Information System (INIS)

    Krischer, W.

    1990-01-01

    The involvement of the EC Commission in the reactor safety research dates back almost to the implementation of the EURATOM Treaty and has thus lasted for thirty years. The need for close collaboration and for general consensus on some crucial problems of concern to the public, has made the role of international organizations and, as far as Europe is concerned, the role of the European Community particularly important. The areas in which the CEC has been active during the last five years are widespread. This is partly due to the fact that, after TMI and Chernobyl, the effort and the interest of the different countries in reactor safety was considerable. Reactor Safety Research represents the proceedings of a seminar held by the Commission at the end of its research programme 1984-88 on reactor safety. As such it gives a comprehensive overview of the recent activities and main results achieved in the CEC Joint Research Centre and in national laboratories throughout Europe on the basis of shared cost actions. In a concluding chapter the book reports on the opinions, expressed during a panel by a group of major exponents, on the needs for future research. The main topics addressed are, with particular reference to Light Water Reactors (LWRS): reliability and risk evaluation, inspection of steel components, primary circuit components end-of-life prediction, and abnormal behaviour of reactor cooling systems. As far as LMFBRs are concerned, the topics covered are: severe accident modelling, material properties and structural behaviour studies. There are 67 pages, all of which are indexed separately. Reactor Safety Research will be of particular interest to reliability and safety engineers, nuclear engineers and technicians, and mechanical and structural engineers. (author)

  14. Widespread abundance of functional bacterial amyloid in Mycolata and other Gram-positive bacteria

    DEFF Research Database (Denmark)

    Jordal, Peter Bruun; Dueholm, Morten Simonsen; Larsen, Poul

    2009-01-01

    extracellular fibrils were also produced. In three cases, FuBA was only revealed after extensive removal of extracellular material by saponification, indicating an integrated attachment within the cellular envelope. Spores from species within the genera Streptomyces, Bacillus and Nocardia were all coated...... analysis. We conclude that amyloid is widespread among Gram-positive bacteria and may in many species constitute a hitherto overlooked integral part of the spores and the cellular envelope....

  15. Anti-Air Warfare Research for Naval Forces

    NARCIS (Netherlands)

    Bloemen, A.A.F.; Witberg, R.

    2000-01-01

    AAW is a warfare area with wide-spread spectrum. Command and Control Systems, sensors, effectors and electronic warfare are integrated to a system, they influence each other and must eventually be effective in coordinated action. This complexity asks for Operations Research methods to measure

  16. Present status of tritium research activities at universities in Japan

    International Nuclear Information System (INIS)

    Kawamura, K.

    1983-01-01

    The behaviours of tritium towards various materials are very similar to those of hydrogen, since tritium is one of the hydrogen isotope. In addition to those properties, tritium shows the radiochemical and radiological reactivities due to an emitted #betta#-ray. The permeability of tritium through various materials is the example of the former. The formation of tritiated methane in tritium stored in stainless steel vessels and the increase of helium content in tritium-bearing metallic materials are the examples of the latter. For these reasons, advanced and somewhat more complicated techniques are required for handling tritium. After the Ministry of Education, Science and Culture (MOE) made an appropriation on Grant-in-Aid for Fusion Research in 1975 year's budget, development of tritium handling technology for fusion reactors have been actively pursued. The specific experiments to be embodied in present research activities are: 1. Measurements of tritium permeation rate through various materials. 2. Fundamental studies on tritium containment materials. 3. Fundamental studies of tritium waste treatment and storage. In this paper, the works achieved under the above research activities are described and some results obtained from experiments are reported. (author)

  17. A review of research activities at the Research Reactor Institute of Kyoto University in view of research publication information

    International Nuclear Information System (INIS)

    Takeuchi, Takayuki; Mizuma, Mitsuo; Kimura, Itsuro.

    1995-01-01

    A database of research publication was constructed for the purpose of grasping all of the research activities at the Research Reactor Institute, Kyoto University. The database named KURRIP collects all of the research publications of the Institute by not only its own staff but also visiting scientists. The publications are in the form of original papers, review papers, papers in proceedings, short notes and letters, synopses over 3 pages presented orally at scientific meeting, books and doctoral theses. At present, the KURRIP database contains the information on 6,210 items which have been published for 30 years since the Institute was established as an interuniversity research institute for joint use of a research reactor and other related large facilities in 1963. By utilizing the KURRIP database, the analyses have been done: (1) affiliation of the authors, (2) kind of publications, (3) classification of publishers, (4) research fields, and (5) experimental facilities. The KURRIP database is now stored in the Data Processing Center of Kyoto University and can be utilized through a computer center at one of the main national universities in Japan. (author)

  18. The Effects of Forest Therapy on Coping with Chronic Widespread Pain: Physiological and Psychological Differences between Participants in a Forest Therapy Program and a Control Group

    Directory of Open Access Journals (Sweden)

    Jin-Woo Han

    2016-02-01

    Full Text Available This study aimed to investigate the effects of a two-day forest therapy program on individuals with chronic widespread pain. Sixty one employees of a public organization providing building and facilities management services within the Seoul Metropolitan area participated in the study. Participants were assigned to an experimental group (n = 33 who participated in a forest therapy program or a control group (n = 28 on a non-random basis. Pre- and post-measures of heart rate variability (HRV, Natural Killer cell (NK cell activity, self-reported pain using the visual analog scale (VAS, depression level using the Beck Depression Inventory (BDI, and health-related quality of life measures using the EuroQol Visual Analog Scale (EQ-VAS were collected in both groups. The results showed that participants in the forest therapy group, as compared to the control group, showed physiological improvement as indicated by a significant increase in some measures of HRV and an increase in immune competence as indicated by NK cell activity. Participants in the forest therapy group also reported significant decreases in pain and depression, and a significant improvement in health-related quality of life. These results support the hypothesis that forest therapy is an effective intervention to relieve pain and associated psychological and physiological symptoms in individuals with chronic widespread pain.

  19. Making Tracks 1.0: Action Researching an Active Transportation Education Program

    Science.gov (United States)

    Robinson, Daniel; Foran, Andrew; Robinson, Ingrid

    2014-01-01

    This paper reports on the results of the first cycle of an action research project. The objective of this action research was to examine the implementation of a school-based active transportation education program (Making Tracks). A two-cycle action research design was employed in which elementary school students' (ages 7-9), middle school…

  20. The activities and prospect of planetary protection research in China

    Science.gov (United States)

    Li, Ming

    2016-07-01

    Planetary protection is an important activities and responsibilities for space exploration. In Chinese manned missions, micro-organism research and protection has been developed in Shenzhou-9, Shenzhou-10 and Tiangong-2 missions. In the experiment facility of Lunar Palace-1, the micro-organism pollution and protection/control technology has been studied. In the lunar sample recovery mission and China Mars mission, the planetary protection has become an important issue. This paper introduced the research about planetary protection in China. The planetary protection activities, strategy and procedures have been suggested for future space exploration program to meet the requirement for planetary protection, such as cabin pollution isolation, pollutant detection, and so on.

  1. Recommendations for the safe use and regulation of radiation sources in industry, medicine, research and teaching

    International Nuclear Information System (INIS)

    1990-01-01

    The use of radiation sources of various types and activities is widespread in industry, medicine, research and teaching, and is increasing yearly. The safety record has been admirable, although incidents have occurred where loss of control of radiation sources has given rise to unplanned exposures to workers, medical patients and members of the public, sometimes with fatal results, while in other situations exposure may not have been as low as reasonably achievable. This publication is intended as a practical aid for all concerned with operational radiation protection connected with the use of radiation sources in industry, medicine, research and teaching, from the point of view of both the user of such sources and the regulatory bodies. Refs, figs

  2. Widespread microplastic ingestion by fish assemblages in tropical estuaries subjected to anthropogenic pressures

    International Nuclear Information System (INIS)

    Vendel, A.L.; Bessa, F.; Alves, V.E.N.; Amorim, A.L.A.; Patrício, J.; Palma, A.R.T.

    2017-01-01

    Our aim was to quantify microplastic ingestion by fish assemblages in two tropical Brazilian estuaries and to evaluate whether biological and ecological factors influence the ingestion of microplastics by fish species. Of 2233 fish from both estuaries (from 69 species) examined in this study, 9% of the individuals (24 species) had microplastics in their gut contents. Microplastic ingestion occurred irrespective of fish size and functional group. The diet of fish species was analyzed based on prey items identified in the fish's full stomach contents and five feeding guilds were defined. Microplastics were common throughout all feeding guilds. Low (average ingestion values 1.06 ± 0.30 items/total fish) but widespread occurrence among estuaries also indicates proliferation of microplastic pollution. Our findings highlight the need to focus on assemblage level studies to understand the real magnitude of the problem and emphasize the urgency of mitigation measures directed at microplastic pollution in estuarine ecosystems. - Highlights: • We analyzed microplastic ingestion in 69 fish species collected along two estuaries. • Microplastic ingestion was widespread in fish assemblages in two tropical estuaries. • Microplastic ingestion was independent of fish size and fish functional groups. • Microplastics were observed in fish from five different feeding guilds. • The level of anthropogenic pressures did not influence microplastic ingestion.

  3. A localized flare of dermatitis may render patch tests uninterpretable in some patients with recently controlled widespread dermatitis.

    Science.gov (United States)

    Magembe, Anna J; Davis, Mark D P; Richardson, Donna M

    2009-01-01

    Patch testing rarely is confounded by localized dermatitis induced in the area being tested (usually the back). Its occurrence renders the interpretation of patch tests impossible. To review our experience of the circumstances in which this phenomenon occurs during patch testing. We retrospectively reviewed patients with this phenomenon who underwent patch testing from January 1, 2002, through June 30, 2006. Of the 3,569 patients tested, 12 (0.34% [9 men and 3 women]) had development of this phenomenon. All patients previously had recent widespread dermatitis that was suppressed temporarily with topical corticosteroids and wet dressings at the time of patch testing. The period between control of the dermatitis and the initiation of patch testing was less than 1 week for all patients. Three patients (25%) had recently discontinued therapy with systemic corticosteroids (less than 1 week earlier). In patients with irritable skin either immediately after widespread dermatitis is controlled or after the cessation of systemic corticosteroid treatment, a flare of dermatitis induced by patch testing may render patch tests unreadable and therefore uninterpretable. To avoid this confounding occurrence, a waiting period between control of widespread dermatitis and initiation of patch testing is advised.

  4. How open science helps researchers succeed

    Science.gov (United States)

    McKiernan, Erin C; Bourne, Philip E; Brown, C Titus; Buck, Stuart; Kenall, Amye; Lin, Jennifer; McDougall, Damon; Nosek, Brian A; Ram, Karthik; Soderberg, Courtney K; Spies, Jeffrey R; Thaney, Kaitlin; Updegrove, Andrew; Woo, Kara H; Yarkoni, Tal

    2016-01-01

    Open access, open data, open source and other open scholarship practices are growing in popularity and necessity. However, widespread adoption of these practices has not yet been achieved. One reason is that researchers are uncertain about how sharing their work will affect their careers. We review literature demonstrating that open research is associated with increases in citations, media attention, potential collaborators, job opportunities and funding opportunities. These findings are evidence that open research practices bring significant benefits to researchers relative to more traditional closed practices. DOI: http://dx.doi.org/10.7554/eLife.16800.001 PMID:27387362

  5. Space Research, Education, and Related Activities In the Space Sciences

    Science.gov (United States)

    Black, David

    2002-01-01

    The mission of this activity, known as the Cooperative Program in Space Sciences (CPSS), is to conduct space science research and leading-edge instrumentation and technology development, enable research by the space sciences communities, and to expedite the effective dissemination of space science research, technology, data, and information to the educational community and the general public. To fulfill this mission, the Universities Space Research Association (USRA) recruits and maintains a staff of scientific researchers, operates a series of guest investigator facilities, organizes scientific meetings and workshops, and encourages various interactions with students and university faculty members. This paper is the final report from this now completed Cooperative Agreement.

  6. Research Activity and Infrastructure of Korea Polar Research Institute: Current and Future Perspectives

    Science.gov (United States)

    Jin, D.; Kim, S.; Lee, H.

    2011-12-01

    The Korea Polar Research Institute (KOPRI) opened the Antarctic King Sejong research station in 1988 at the King George Island off the Antarctic Peninsula and started the polar research mainly in the fields of biology and geology with some atmosphere observations. To extend the view of polar research, the KOPRI opened the Arctic Dasan research station at Ny-Alesund, Spitsbergen Island in 2002 and has studied the rapid climate change diagnostics and some microbiological observation. The KOPRI is now expanding the Arctic research into Alaska and Canada under the international collaboration, and planning to outreach to Russia to monitor the change in permafrost and to understand its impact on global warming. To deepen the views of polar research including the ice covered oceans in both poles, the ice-breaking vessel, the ARAON of about 7000 ton, was launched recently and successfully finished the Arctic and Antarctic cruises for research activity on all perspectives of ocean sciences and support for the King Sejong station. The KOPRI is now building another Antarctic research station, called Jangbogo, at the Terra Nova Bay off the Ross Sea and plan to open the station at the March of 2014. By building the second Antarctic station together with the ARAON, the KOPRI will focus its research on understanding the rapid climate change in west Antarctica such as to monitor the calving of the Larsen Ice shelf, rapid melting of Pine Island Glacier, and upper atmosphere, to study the sea ice and ecosystem change in the Amundsen Sea and the role of the southern annular mode in the west Antarctic warming, upper atmosphere and climate change, to reconstruct paleoclimate records from ice and sediment cores.

  7. NDA generic research programme for higher activity waste management issues - 16390

    International Nuclear Information System (INIS)

    McKinney, James; Brownridge, Melanie

    2009-01-01

    NDA has a responsibility to ensure decommissioning activities are sufficiently technically underpinned and appropriate Research and Development (Rand D) is carried out. The NDA funds research and development (R and D) indirectly via the Site Licence Companies (SLCs) or directly. The main component of directly funded R and D is the NDA Direct Research Portfolio (DRP). The DRP is split into four framework areas: - University Interactions; - Waste Processing; - Material Characterisation; - Actinide and Strategic Nuclear Materials. These four framework areas were competed through an Official Journal of European Union (OJEU) process in 2008. Although all four areas involve waste management, Waste Processing and Material Characterisation specifically deal with Higher Activity Waste (HAW) waste management issues. The Waste Processing area was awarded to three groups: (i) National Nuclear Laboratory (NNL), (ii) Consortium led by Hyder Consulting Ltd, and (iii) Consortium led by UKAEA Ltd. The Material Characterisation area was awarded to three groups: (i) NNL, (ii) Serco, and (iii) Consortium led by UKAEA Ltd. The initial work in Waste Processing and Material Characterisation was centered on establishing a forward research programme to address the generic needs of the UK civil nuclear industry and the NDA strategic drivers for waste management and land quality. This has been achieved by the four main framework contractors from the Waste Processing and Materials Characterisation areas working together with the NDA to identify the key research themes and begin the development of the NDA's HAW Management Research Programme. The process also involves active engagement with both industry and regulators via the Nuclear Waste Research Forum (NWRF). The NDA's HAW Management Research Programme includes a number of themes: - Optimisation of Interim Store Operation and Design; - Alternative Waste Encapsulants; - Waste Package Integrity; - Alternative Waste treatment methods

  8. Isolation of polymorphic microsatellite markers and tests of cross-amplification in four widespread European calcicole ferns

    NARCIS (Netherlands)

    Groot, de G.A.; Korpelainen, H.; Wubs, E.R.J.; Erkens, R.H.J.

    2011-01-01

    Premise of the study: Studies on the biogeography and population genetics of the widespread European rock ferns Asplenium scolopendrium , A. trichomanes subsp. quadrivalens , Polystichum setiferum , and P. aculeatum would potentially yield interesting new insights into the colonization capacities of

  9. Activities on safety for the cross-cutting issue of research reactors in the IAEA

    International Nuclear Information System (INIS)

    Perrotta, J.A.; Boado Magan, H.J.

    2003-01-01

    IAEA activities in the field of research reactor safety are included in the programme of the Division of Nuclear Installations Safety and implemented by the Engineering Safety Section through its Research Reactor Safety Unit. Following the objectives of the Division, the results of the IAEA missions and the recommendations from International Advisory Groups, the IAEA has conducted in recent years a certain number of activities aiming to enhance the safety of research reactors. The following activities are discussed in this paper: (a) the new Requirements for the Safety of Research Reactors, main features and differences with previous standards (SS-35-S1 and SS-35-S2) and the grading approach for implementation; (b) new documents being developed (safety guides, safety reports and TECDOCs); (c) activities related to the Incident Reporting System for Research Reactor (IRSRR); (d) the new features implemented for the (Integrated Safety Assessment of Research Reactors) INSARR missions; (e) the Code of Conduct on the Safety of Research Reactors developed, following the General Conference Resolution GC(45)/RES/10; and (f) the survey on the safety of research reactors conducted in the year 2002 and the results obtained. (author)

  10. Widespread decline of Congo rainforest greenness in the past decade.

    Science.gov (United States)

    Zhou, Liming; Tian, Yuhong; Myneni, Ranga B; Ciais, Philippe; Saatchi, Sassan; Liu, Yi Y; Piao, Shilong; Chen, Haishan; Vermote, Eric F; Song, Conghe; Hwang, Taehee

    2014-05-01

    Tropical forests are global epicentres of biodiversity and important modulators of climate change, and are mainly constrained by rainfall patterns. The severe short-term droughts that occurred recently in Amazonia have drawn attention to the vulnerability of tropical forests to climatic disturbances. The central African rainforests, the second-largest on Earth, have experienced a long-term drying trend whose impacts on vegetation dynamics remain mostly unknown because in situ observations are very limited. The Congolese forest, with its drier conditions and higher percentage of semi-evergreen trees, may be more tolerant to short-term rainfall reduction than are wetter tropical forests, but for a long-term drought there may be critical thresholds of water availability below which higher-biomass, closed-canopy forests transition to more open, lower-biomass forests. Here we present observational evidence for a widespread decline in forest greenness over the past decade based on analyses of satellite data (optical, thermal, microwave and gravity) from several independent sensors over the Congo basin. This decline in vegetation greenness, particularly in the northern Congolese forest, is generally consistent with decreases in rainfall, terrestrial water storage, water content in aboveground woody and leaf biomass, and the canopy backscatter anomaly caused by changes in structure and moisture in upper forest layers. It is also consistent with increases in photosynthetically active radiation and land surface temperature. These multiple lines of evidence indicate that this large-scale vegetation browning, or loss of photosynthetic capacity, may be partially attributable to the long-term drying trend. Our results suggest that a continued gradual decline of photosynthetic capacity and moisture content driven by the persistent drying trend could alter the composition and structure of the Congolese forest to favour the spread of drought-tolerant species.

  11. Activation of TRIGA Mark II research reactor concrete shield

    International Nuclear Information System (INIS)

    Zagar, Tomaz; Ravnik, Matjaz; Bozic, Matjaz

    2002-01-01

    To determine neutron activation inside the TRIGA research reactor concrete body a special sample-holder for irradiation inside horizontal channel was developed and tested. In the sample-holder various samples can be irradiated at different concrete shielding depths. In this paper the description of the sample-holder, experiment conditions and results of long-lived activation measurements are given. Long-lived neutron-induced gamma-ray-emitting radioactive nuclides in the samples were measured with HPGe detector. The most active long-lived radioactive nuclides in ordinary concrete samples were found to be 60 Co and 152 Eu and in barytes concrete samples 60 Co, 152 Eu and 133 Ba. Measured activity density of all nuclides was found to decrease almost linearly with depth in logarithmic scale. (author)

  12. Danish Labour Market Activation Policies

    DEFF Research Database (Denmark)

    Kvist, Jon; Pedersen, Lisbeth

    2007-01-01

    Under the heading of flexicurity, Danish labour market activation policies are receiving international attention because of their perceived ability both to curb unemployment and to boost employment. Indeed, the objectives, target groups and design of activation policy have undergone a remarkable...... not only active labour market policies but also social and integration policies. Despite widespread popularity and belief in the positive effects of activation, little is actually known about its overall impact on the Danish economy....

  13. Synergy between research activity and management procedures in an industrial waste treatment

    International Nuclear Information System (INIS)

    Bertanza, G.; Collivignarelli, M.C.; Zanaboni, S.

    2006-01-01

    The optimization of operation criteria for centralized industrial waste treatment plants is a difficult task. Experimental research can be a useful tool for understanding how to carry out this optimization process; however, in order to obtain proper solution, a very close connection must been observed activity and the field (e.g. practical application at the full scale). In this paper a three years successful experience is described: the research was carried out in an industrial waste treatment facility located in Northern Italy. Thanks to a close interaction between management and research activities, a significant synergy was achieved: in fact, interesting and original suggestions for the research arose from plant monitoring, and the first findings of the research have already led to important improvements in the full scale plant management [it

  14. Report of the summative evaluation by the advisory committee on research support and collaborative activities

    International Nuclear Information System (INIS)

    2005-03-01

    The Research Evaluation Committee of the Japan Atomic Energy Research Institute (JAERI) set up an Advisory Committee on Research Support and Collaborative Activities in accordance with the 'Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations. The Advisory Committee on Research Support and Collaborative Activities evaluated the adequacy of the plans of research support and collaborative activities to be succeeded from JAERI to a new research institute which will be established by integration of JAERI and the Japan Nuclear Cycle Development Institute (JNC). The Advisory Committee consisted of nine specialists from outside the JAERI conducted its activities from June 2004 to August 2004. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Advisory Committee meeting which was held on July 21, 2004, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Advisory Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on December 1, 2004. This report describes the result of the evaluation by the Advisory Committee on Research Support and Collaborative Activities. (author)

  15. Research data management and libraries: relationships, activities, drivers and influences.

    Directory of Open Access Journals (Sweden)

    Stephen Pinfield

    Full Text Available The management of research data is now a major challenge for research organisations. Vast quantities of born-digital data are being produced in a wide variety of forms at a rapid rate in universities. This paper analyses the contribution of academic libraries to research data management (RDM in the wider institutional context. In particular it: examines the roles and relationships involved in RDM, identifies the main components of an RDM programme, evaluates the major drivers for RDM activities, and analyses the key factors influencing the shape of RDM developments. The study is written from the perspective of library professionals, analysing data from 26 semi-structured interviews of library staff from different UK institutions. This is an early qualitative contribution to the topic complementing existing quantitative and case study approaches. Results show that although libraries are playing a significant role in RDM, there is uncertainty and variation in the relationship with other stakeholders such as IT services and research support offices. Current emphases in RDM programmes are on developments of policies and guidelines, with some early work on technology infrastructures and support services. Drivers for developments include storage, security, quality, compliance, preservation, and sharing with libraries associated most closely with the last three. The paper also highlights a 'jurisdictional' driver in which libraries are claiming a role in this space. A wide range of factors, including governance, resourcing and skills, are identified as influencing ongoing developments. From the analysis, a model is constructed designed to capture the main aspects of an institutional RDM programme. This model helps to clarify the different issues involved in RDM, identifying layers of activity, multiple stakeholders and drivers, and a large number of factors influencing the implementation of any initiative. Institutions may usefully benchmark their

  16. Research data management and libraries: relationships, activities, drivers and influences.

    Science.gov (United States)

    Pinfield, Stephen; Cox, Andrew M; Smith, Jen

    2014-01-01

    The management of research data is now a major challenge for research organisations. Vast quantities of born-digital data are being produced in a wide variety of forms at a rapid rate in universities. This paper analyses the contribution of academic libraries to research data management (RDM) in the wider institutional context. In particular it: examines the roles and relationships involved in RDM, identifies the main components of an RDM programme, evaluates the major drivers for RDM activities, and analyses the key factors influencing the shape of RDM developments. The study is written from the perspective of library professionals, analysing data from 26 semi-structured interviews of library staff from different UK institutions. This is an early qualitative contribution to the topic complementing existing quantitative and case study approaches. Results show that although libraries are playing a significant role in RDM, there is uncertainty and variation in the relationship with other stakeholders such as IT services and research support offices. Current emphases in RDM programmes are on developments of policies and guidelines, with some early work on technology infrastructures and support services. Drivers for developments include storage, security, quality, compliance, preservation, and sharing with libraries associated most closely with the last three. The paper also highlights a 'jurisdictional' driver in which libraries are claiming a role in this space. A wide range of factors, including governance, resourcing and skills, are identified as influencing ongoing developments. From the analysis, a model is constructed designed to capture the main aspects of an institutional RDM programme. This model helps to clarify the different issues involved in RDM, identifying layers of activity, multiple stakeholders and drivers, and a large number of factors influencing the implementation of any initiative. Institutions may usefully benchmark their activities against the

  17. [Activities of Research Institute for Advanced Computer Science

    Science.gov (United States)

    Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

    2001-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administrations missions. RIACS is located at the NASA Ames Research Center, Moffett Field, California. RIACS research focuses on the three cornerstones of IT research necessary to meet the future challenges of NASA missions: 1. Automated Reasoning for Autonomous Systems Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth. 2. Human-Centered Computing Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities. 3. High Performance Computing and Networking Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to analysis of large scientific datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply IT research to a variety of NASA application domains. RIACS also engages in other activities, such as workshops, seminars, visiting scientist programs and student summer programs, designed to encourage and facilitate collaboration between the university and NASA IT research communities.

  18. Antimicrobial activity and phytochemical characterization of Carya illinoensis.

    Science.gov (United States)

    Bottari, Nathieli Bianchin; Lopes, Leonardo Quintana Soares; Pizzuti, Kauana; Filippi Dos Santos Alves, Camilla; Corrêa, Marcos Saldanha; Bolzan, Leandro Perger; Zago, Adriana; de Almeida Vaucher, Rodrigo; Boligon, Aline Augusti; Giongo, Janice Luehring; Baldissera, Matheus Dellaméa; Santos, Roberto Christ Vianna

    2017-03-01

    Carya illinoensis is a widespread species, belonging to the Juglandaceae family, commonly known as Pecan. Popularly, the leaves have been used in the treatment of smoking as a hypoglycemic, cleansing, astringent, keratolytic, antioxidant, and antimicrobial agent. The following research aimed to identify for the first time the phytochemical compounds present in the leaves of C. illinoensis and carry out the determination of antimicrobial activity of aqueous and ethanolic extracts. The antimicrobial activity was tested against 20 microorganisms by determining the minimum inhibitory concentration (MIC). Phenolic acids (gallic acid and ellagic acid), flavonoids (rutin), and tannins (catechins and epicatechins) were identified by HPLC-DAD and may be partially responsible for the antimicrobial activity against Gram-positive, Gram-negative, and yeast. The results showed MIC values between 25 mg/mL and 0.78 mg/mL. The extracts were also able to inhibit the production of germ tubes by Candida albicans. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Leadership: the critical success factor in the rise or fall of useful research activity.

    Science.gov (United States)

    Henderson, Amanda; Winch, Sarah; Holzhauser, Kerri

    2009-12-01

    To describe how momentum towards building research capacity has developed through aligning research activity with executive responsibility via strategic planning processes that direct operational structures and processes for research activity. Reflecting on the development of research capacity over many years at complex tertiary referral hospitals reveals that building nursing knowledge is too important to be left to chance or whim but needs a strategic focus, appropriate resourcing and long-term sustainability through infrastructure. A number of key approaches we uncovered as successful include: (i) articulation of questions consistent with the strategic direction of the health context that can be addressed through research evidence; (ii) engagement and dissemination through making research meaningful; and (iii) feedback that informs the executive about the contribution of research activity to guide policy and practice decisions. Leadership teams need to ensure that the development of research knowledge is a strategic priority. The focus also needs to be more broadly on creating research capacity than focussing on small operational issues. Research capacity is developed when it is initiated, supported and monitored by leadership.

  20. Brain-(Not) Based Education: Dangers of Misunderstanding and Misapplication of Neuroscience Research

    Science.gov (United States)

    Alferink, Larry A.; Farmer-Dougan, Valeri

    2010-01-01

    Oversimplification or inappropriate interpretation of complex neuroscience research is widespread among curricula claiming that brain-based approaches are effective for improved learning and retention. We examine recent curricula claiming to be based on neuroscience research, discuss the implications of such misinterpretation for special…

  1. Considerations for higher efficiency and productivity in research activities.

    Science.gov (United States)

    Forero, Diego A; Moore, Jason H

    2016-01-01

    There are several factors that are known to affect research productivity; some of them imply the need for large financial investments and others are related to work styles. There are some articles that provide suggestions for early career scientists (PhD students and postdocs) but few publications are oriented to professors about scientific leadership. As academic mentoring might be useful at all levels of experience, in this note we suggest several key considerations for higher efficiency and productivity in academic and research activities. More research is needed into the main work style features that differentiate highly productive scientists and research groups, as some of them could be innate and others could be transferable. As funding agencies, universities and research centers invest large amounts of money in order to have a better scientific productivity, a deeper understanding of these factors will be of high academic and societal impact.

  2. Widespread ground motion distribution caused by rupture directivity during the 2015 Gorkha, Nepal earthquake

    Science.gov (United States)

    Koketsu, Kazuki; Miyake, Hiroe; Guo, Yujia; Kobayashi, Hiroaki; Masuda, Tetsu; Davuluri, Srinagesh; Bhattarai, Mukunda; Adhikari, Lok Bijaya; Sapkota, Soma Nath

    2016-06-01

    The ground motion and damage caused by the 2015 Gorkha, Nepal earthquake can be characterized by their widespread distributions to the east. Evidence from strong ground motions, regional acceleration duration, and teleseismic waveforms indicate that rupture directivity contributed significantly to these distributions. This phenomenon has been thought to occur only if a strike-slip or dip-slip rupture propagates to a site in the along-strike or updip direction, respectively. However, even though the earthquake was a dip-slip faulting event and its source fault strike was nearly eastward, evidence for rupture directivity is found in the eastward direction. Here, we explore the reasons for this apparent inconsistency by performing a joint source inversion of seismic and geodetic datasets, and conducting ground motion simulations. The results indicate that the earthquake occurred on the underthrusting Indian lithosphere, with a low dip angle, and that the fault rupture propagated in the along-strike direction at a velocity just slightly below the S-wave velocity. This low dip angle and fast rupture velocity produced rupture directivity in the along-strike direction, which caused widespread ground motion distribution and significant damage extending far eastwards, from central Nepal to Mount Everest.

  3. Engaging families in physical activity research: a family-based focus group study.

    Science.gov (United States)

    Brown, Helen Elizabeth; Schiff, Annie; van Sluijs, Esther M F

    2015-11-25

    Family-based interventions present a much-needed opportunity to increase children's physical activity levels. However, little is known about how best to engage parents and their children in physical activity research. This study aimed to engage with the whole family to understand how best to recruit for, and retain participation in, physical activity research. Families (including a 'target' child aged between 8 and 11 years, their parents, siblings, and others) were recruited through schools and community groups. Focus groups were conducted using a semi-structured approach (informed by a pilot session). Families were asked to order cards listing the possible benefits of, and the barriers to, being involved in physical activity research and other health promotion activities, highlighting the items they consider most relevant, and suggesting additional items. Duplicate content analysis was used to identify transcript themes and develop a coding frame. Eighty-two participants from 17 families participated, including 17 'target' children (mean age 9.3 ± 1.1 years, 61.1% female), 32 other children and 33 adults (including parents, grandparents, and older siblings). Social, health and educational benefits were cited as being key incentives for involvement in physical activity research, with emphasis on children experiencing new things, developing character, and increasing social contact (particularly for shy children). Children's enjoyment was also given priority. The provision of child care or financial reward was not considered sufficiently appealing. Increased time commitment or scheduling difficulties were quoted as the most pertinent barriers to involvement (especially for families with several children), but parents commented these could be overcome if the potential value for children was clear. Lessons learned from this work may contribute to the development of effective recruitment and retention strategies for children and their families. Making the wide

  4. Widespread Natural Occurrence of Hydroxyurea in Animals.

    Directory of Open Access Journals (Sweden)

    David I Fraser

    Full Text Available Here we report the widespread natural occurrence of a known antibiotic and antineoplastic compound, hydroxyurea in animals from many taxonomic groups. Hydroxyurea occurs in all the organisms we have examined including invertebrates (molluscs and crustaceans, fishes from several major groups, amphibians and mammals. The species with highest concentrations was an elasmobranch (sharks, skates and rays, the little skate Leucoraja erinacea with levels up to 250 μM, high enough to have antiviral, antimicrobial and antineoplastic effects based on in vitro studies. Embryos of L. erinacea showed increasing levels of hydroxyurea with development, indicating the capacity for hydroxyurea synthesis. Certain tissues of other organisms (e.g. skin of the frog (64 μM, intestine of lobster (138 μM gills of the surf clam (100 μM had levels high enough to have antiviral effects based on in vitro studies. Hydroxyurea is widely used clinically in the treatment of certain human cancers, sickle cell anemia, psoriasis, myeloproliferative diseases, and has been investigated as a potential treatment of HIV infection and its presence at high levels in tissues of elasmobranchs and other organisms suggests a novel mechanism for fighting disease that may explain the disease resistance of some groups. In light of the known production of nitric oxide from exogenously applied hydroxyurea, endogenous hydoxyurea may play a hitherto unknown role in nitric oxide dynamics.

  5. Widespread Natural Occurrence of Hydroxyurea in Animals.

    Science.gov (United States)

    Fraser, David I; Liu, Kyle T; Reid, Bryan J; Hawkins, Emily; Sevier, Andrew; Pyle, Michelle; Robinson, Jacob W; Ouellette, Pierre H R; Ballantyne, James S

    2015-01-01

    Here we report the widespread natural occurrence of a known antibiotic and antineoplastic compound, hydroxyurea in animals from many taxonomic groups. Hydroxyurea occurs in all the organisms we have examined including invertebrates (molluscs and crustaceans), fishes from several major groups, amphibians and mammals. The species with highest concentrations was an elasmobranch (sharks, skates and rays), the little skate Leucoraja erinacea with levels up to 250 μM, high enough to have antiviral, antimicrobial and antineoplastic effects based on in vitro studies. Embryos of L. erinacea showed increasing levels of hydroxyurea with development, indicating the capacity for hydroxyurea synthesis. Certain tissues of other organisms (e.g. skin of the frog (64 μM), intestine of lobster (138 μM) gills of the surf clam (100 μM)) had levels high enough to have antiviral effects based on in vitro studies. Hydroxyurea is widely used clinically in the treatment of certain human cancers, sickle cell anemia, psoriasis, myeloproliferative diseases, and has been investigated as a potential treatment of HIV infection and its presence at high levels in tissues of elasmobranchs and other organisms suggests a novel mechanism for fighting disease that may explain the disease resistance of some groups. In light of the known production of nitric oxide from exogenously applied hydroxyurea, endogenous hydoxyurea may play a hitherto unknown role in nitric oxide dynamics.

  6. ECUT: Energy Conversion and Utilization Technologies program. Industry, university and research interest in the US Department of Energy ECUT biocatalysis research activity

    Science.gov (United States)

    Wilcox, R. E.

    1983-01-01

    The results of a Research Opportunity Notice (RON) disseminated by the Jet Propulsion Laboratory for the U.S. Department of Energy Conversion and Utilization Technologies (ECUT) Program's Biocatalysis Research Activity are presented. The RON was issued in late April of 1983 and solicited expressions of interest from petrochemical and chemical companies, bioengineering firms, biochemical engineering consultants, private research laboratories, and universities for participating in a federal research program to investigate potential applications of biotechnology in producing chemicals. The RON results indicate that broad interest exists within the nation's industry, universities, and research institutes for the Activity and its planned research and development program.

  7. Storytelling as a way for humanizing research methods

    OpenAIRE

    Grenness, Tor

    2016-01-01

    This is an Open Access journal. The article is aslo available from www.idrcentre.org This article examines how the use of storytelling can serve as a pedagogical strategy in the teaching of research methods. Research methods and statistics anxiety is fairly widespread among students in higher education. Introducing storytelling has been found to decrease this anxiety. The term “humanizing research methods” implies a focus on students’ needs that goes beyond transferring knowledge of the co...

  8. Summary reports of activities under visiting research program (1992)

    International Nuclear Information System (INIS)

    1992-09-01

    Now the summary report of activities under visiting research program in the Research Reactor Institute, Kyoto University, in fiscal year 1991 has been put in order and published. As compared with the past reports, in the report of this year, pages increased and the style changed, but this is due to the change of the method of adopting researches to that throughout one year from fiscal year 1991. So far one page was allotted to every subject, but this limit was relaxed according to the contents. This style is not yet fixed. As well known, discussion is going on about the way the research reactor and the Research Reactor Institute should be. As for this summary report, in order to receive the international evaluation, it was decided to publish the report in English from fiscal year 1992, and the Progress Report on the research by the Institute personnel is included in it. In this report, 98 summaries of the researches using the KUR and 15 summaries of the researches using the KUCA are collected. One summary which was not reported in fiscal year 1990 is added. (K.I.)

  9. Accelerator-driven nuclear synergetic systems-an overview of the research activities in Sweden

    International Nuclear Information System (INIS)

    Conde, H.; Baecklin, A.; Carius, S.

    1995-01-01

    The rapid development of the accelerator technology which enables the construction of reliable and very intense neutron sources has initiated a growing interest for accelerator driven transmutation systems in Sweden. After the Specialist Meeting on Accelerator-Driven Transmutation Technology for Radwaste and other Applications on 24-28 June 1991 at Saltsjoebaden, Sweden, the research activities oriented towards accelerator-driven systems have been started at several research centers in Sweden. Also the governmental agencies responsible for the spent fuel policy showed a positive attitude to these activities through a limited financial support, particularly for studies of the safety aspects of these systems. Also the nuclear power industry and utilities show a positive interest in the research on these concepts. The present paper presents an overview of the Swedish research activities on accelerator-driven systems and the proposed future coordination, organizations and prospects for this research in the context of the national nuclear energy and spent fuel policy. The Swedish perspective for international cooperation is also described

  10. Accelerator-driven nuclear synergetic systems-an overview of the research activities in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Conde, H.; Baecklin, A.; Carius, S. [Uppsala Univ. (Sweden)] [and others

    1995-10-01

    The rapid development of the accelerator technology which enables the construction of reliable and very intense neutron sources has initiated a growing interest for accelerator driven transmutation systems in Sweden. After the Specialist Meeting on Accelerator-Driven Transmutation Technology for Radwaste and other Applications on 24-28 June 1991 at Saltsjoebaden, Sweden, the research activities oriented towards accelerator-driven systems have been started at several research centers in Sweden. Also the governmental agencies responsible for the spent fuel policy showed a positive attitude to these activities through a limited financial support, particularly for studies of the safety aspects of these systems. Also the nuclear power industry and utilities show a positive interest in the research on these concepts. The present paper presents an overview of the Swedish research activities on accelerator-driven systems and the proposed future coordination, organizations and prospects for this research in the context of the national nuclear energy and spent fuel policy. The Swedish perspective for international cooperation is also described.

  11. Summary of activities of the Research Department 1984

    International Nuclear Information System (INIS)

    1989-01-01

    This annual report of the Research Department describes the activities performed during 1984 in the following fields: Physics, Reactor Chemistry, Radiobiology, Prospective and Special Studies, Biomathematics, Labelled Molecules and Radiochemistry. During this period the first heavy ion beam in the accelerator Tandar was obtained. A list of publications made by the Department this year is enclosed. (M.E.L.) [es

  12. What Research Says about Small Classes and Their Effects. In Pursuit of Better Schools: What Research Says.

    Science.gov (United States)

    Biddle, Bruce J.; Berliner, David C.

    Interest in class size is widespread today. Debates often take place about "ideal" class size. Controversial efforts to reduce class size have appeared at both the federal level and in various states around the nation. This paper reviews research on class size and discusses findings, how these findings can be explained, and policy implications.…

  13. ORGANIZATIONAL STRUCTURE OF RESEARCH PROJECT ACTIVITIES PERFORMED AT MEDICAL UNIVERSITIES IN BULGARIA.

    Directory of Open Access Journals (Sweden)

    Svetoslav Garov

    2013-07-01

    Full Text Available Introduction: There are five Bulgarian medical universities in the cities of Sofia, Plovdiv, Varna, Pleven and Stara Zagora. A major priority of medical universities is to encourage research activities mainly aimed at preparation and implementation of research projects. Projects are managed by the participating organizations called “beneficiaries”. Beneficiaries develop projects, apply for finances and if approved they implement those projects.Aim: The purpose of our study is to examine the organizational structure of research project activities on the macro level and on the micro level in Bulgarian medical universities.Material and methods: In order to define the separate elements of the organizational structure and to analyze the relations and interaction between them we have applied a documentary and sociological approach. Results: During the last six years there was a significant increase in the number and the overall annual financial value of the projects performed at medical universities in Bulgaria. The reasons for such increase are: managers realizing the advantages of and benefits from the implementation of research projects ensuring high quality modernization of research units’ equipment and facilities; access to innovative technologies; development of interdisciplinary relations, etc. Benefits arising from improved results motivate us to consider as appropriate some additional investments aimed at increasing the number of team members and further optimization of the currently existing structures (research centers in charge of research with the purpose of achieving even better results in this particular field. Conclusion: The role of research project activities in medical universities’ research field is of vital importance for the educational institutions’ success. Taking into consideration the changed conditions, European possibilities and the highly competitive environment, realizing this aspect will be essential for the

  14. Severe accident research activities at Helmholtz-Zentrum Dresden-Rossendorf (HZDR)

    Energy Technology Data Exchange (ETDEWEB)

    Wilhelm, Polina; Jobst, Matthias; Schaefer, Frank; Kliem, Soeren [Helmholtz-Zentrum Dresden-Rossendorf e.V., Dresden (Germany)

    2016-05-15

    In the frame of the nuclear safety research program of the Helmholtz Association HZDR performs fundamental and applied research to assess and to reduce the risks related to the nuclear fuel cycle and the production of electricity in nuclear power plants. One of the research topics focuses on the safety aspects of current and future reactor designs. This includes the development and application of methods for analyses of transients and postulated accidents, covering the whole spectrum from normal operation till severe accident sequences including core degradation. This paper gives an overview of the severe accident research activities at the Reactor Safety Division at the Institute of Resource Ecology.

  15. Active learning about research methodology in engineering education

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang

    Research methodology and theory of science have become important teaching subjects en engineering education as well as in higher education in general. This is rooted in the transition to a knowledge society. Today, it is argued by many that we are well on the way to an era beyond modernity...... of science if often not favored subjects by engineering students, who tend to find the subjects abstract. Thus, the students are often very engaged in the subjects, nor are textbooks or teaching very engaging. This poster asks how we can promote active learning in research methodology and theory of science...... and the sort of industrial economy that came with it. Whatever else the new era brings – the globalization of risks, environmental problems, new technologies, etc. – knowledge and the ability to seek, produce, apply and transform knowledge is of huge importance. However, research methodology and theory...

  16. Monte Carlo reference data sets for imaging research: Executive summary of the report of AAPM Research Committee Task Group 195

    NARCIS (Netherlands)

    Sechopoulos, I.; Ali, E.S.; Badal, A.; Badano, A.; Boone, J.M.; Kyprianou, I.S.; Mainegra-Hing, E.; McMillan, K.L.; McNitt-Gray, M.F.; Rogers, D.W.; Samei, E.; Turner, A.C.

    2015-01-01

    The use of Monte Carlo simulations in diagnostic medical imaging research is widespread due to its flexibility and ability to estimate quantities that are challenging to measure empirically. However, any new Monte Carlo simulation code needs to be validated before it can be used reliably. The type

  17. Geophysical evidence for widespread reversely magnetised pyroclastics in the western Taupo Volcanic Zone (New Zealand)

    International Nuclear Information System (INIS)

    Soengkono, S.; Hochstein, M.P.; Smith, I.E.M.; Itaya, T.

    1992-01-01

    Low-altitude aeromagnetic data show that negative residual anomalies are widespread over the western Taupo Volcanic Zone, New Zealand. Paleomagnetic study of eight rhyolitic ignimbrite units and two lava flows which are exposed in this area, together with new K-Ar dates of four of the ignimbrite units, indicate that the two lava units and seven of the ignimbrite units were erupted during the Matuyama geomagnetic epoch (>0.73 Ma B.P.) and suggest that rhyolitic volcanism in the western Taupo Volcanic Zone began as early as 1.6 Ma B.P. These results provide the basis for an interpretation of our aeromagnetic data which confirms the hypothesis that the magnetic anomalies observed in the western Taupo Volcanic Zone are caused by widespread, thick, reversely magnetised pyroclastic and lava flows. Magnetic modelling also allows thickness estimates of the younger, normally magnetised cover rocks which reach a maximum thickness of the order of 0.5 km in the Mangakino area. The magnetic structure of these volcanic rocks defines approximately the lateral extent of the Mangakino Volcanic Centre. (author). 41 refs., 2 figs., 3 tabs

  18. Conceptualizing and Defining the Intention Construct for Future Physical Activity Research.

    Science.gov (United States)

    Rhodes, Ryan E; Rebar, Amanda L

    2017-10-01

    Intention has been an extremely important concept in physical activity theory and research but is complicated by a double-barreled definition of a decision to perform physical activity and the commitment to enact that decision. We put forth the hypothesis that these separate meanings have different measurement requirements, are situated in distinctly different intention-based models, and show discrete findings when explaining physical activity motives.

  19. Nuclear Physics Research Activity In Vietnam During Period From 2005 To 2007

    International Nuclear Information System (INIS)

    Tran Duc Thiep

    2008-01-01

    During the recent years though the difficult conditions as the limit in research budget, the lack in experimental facilities and in manpower, the Nuclear Physics Research in Vietnam still continues to develop and has achieved promising results. This expresses the efforts from the Government as well as from the nuclear physics scientists. In this report we would like to present the Nuclear Physics Research Activity and the achieved results in Vietnam during period from 2005 to 2007 in following directions: Nuclear Reaction and Structure, Nuclear Matter and Nuclear Data, Nuclear Reactor Physics, Nuclear Physics Research based on Accelerators, Physics of Cosmic Rays, Nuclear Physics Related Researches. The report also concerns the problems of manpower, the joining of research institutes in the Country and the expansion of international collaborations in the coming period of the Nuclear Physics Research Activity. The Report was prepared mainly on the basis of the reports that will be presented at the 7th National Conference on Nuclear Science and Technology, held from 30-31 August 2007 in Danang city. (author)

  20. Statistical Modeling Suggests that Antiandrogens in Effluents from Wastewater Treatment Works Contribute to Widespread Sexual Disruption in Fish Living in English Rivers

    Science.gov (United States)

    Jobling, Susan; Burn, Robert. W.; Thorpe, Karen; Williams, Richard; Tyler, Charles

    2009-01-01

    Background The widespread occurrence of feminized male fish downstream of some wastewater treatment works has led to substantial interest from ecologists and public health professionals. This concern stems from the view that the effects observed have a parallel in humans, and that both phenomena are caused by exposure to mixtures of contaminants that interfere with reproductive development. The evidence for a “wildlife–human connection” is, however, weak: Testicular dysgenesis syndrome, seen in human males, is most easily reproduced in rodent models by exposure to mixtures of antiandrogenic chemicals. In contrast, the accepted explanation for feminization of wild male fish is that it results mainly from exposure to steroidal estrogens originating primarily from human excretion. Objectives We sought to further explore the hypothesis that endocrine disruption in fish is multicausal, resulting from exposure to mixtures of chemicals with both estrogenic and antiandrogenic properties. Methods We used hierarchical generalized linear and generalized additive statistical modeling to explore the associations between modeled concentrations and activities of estrogenic and antiandrogenic chemicals in 30 U.K. rivers and feminized responses seen in wild fish living in these rivers. Results In addition to the estrogenic substances, antiandrogenic activity was prevalent in almost all treated sewage effluents tested. Further, the results of the modeling demonstrated that feminizing effects in wild fish could be best modeled as a function of their predicted exposure to both antiandrogens and estrogens or to antiandrogens alone. Conclusion The results provide a strong argument for a multicausal etiology of widespread feminization of wild fish in U.K. rivers involving contributions from both steroidal estrogens and xenoestrogens and from other (as yet unknown) contaminants with antiandrogenic properties. These results may add further credence to the hypothesis that endocrine

  1. Reprioritizing current research trends in medical education: a reflection on research activities in Saudi Arabia.

    Science.gov (United States)

    Obeidat, Akef S; Alhaqwi, Ali Ibrahim; Abdulghani, Hamza Mohammad

    2015-04-01

    There are numerous national efforts to determine and develop research priorities of medical education in Saudi Arabia. These priorities were first proposed in 2010 by "Dr Al-Khuli's Chair for Developing Medical Education in Saudi Arabia". The proposed priority domains were: curriculum, students, faculty, and quality assurance and accreditation. To investigate publications in medical education at the national and international levels in areas relating to these proposed priorities. Electronic search within PubMed database for papers relating to each domain of priority was conducted at national and international levels in the last three years, using the same keywords as the priority domains, but only confined to undergraduate medical education. Out of 3145 articles retrieved when searching with keyword as broad as "undergraduate medical curriculum" only 81 articles worldwide and 3 articles from Saudi Arabia were dealing with curriculum related issues as a whole. Further search on the sub-domains "effective strategies to manage undergraduate curriculum" and "undergraduate medical education models", resulted in the retrieval of few articles worldwide and none from Saudi Arabia. At the national level, there were 63 publications from Saudi Arabia that were either course (topic)-specific or could not be classified under the four domains specified by Dr Al-Khuli's Chair. Research activities in medical education in Saudi Arabia in the last 3 years showed diversity and lack of focus in the research priorities. Efforts of academic and research centers should continue to monitor and encourage these activities toward achieving the recommended priorities.

  2. Physical Activity of Youth with Intellectual Disability: Review and Research Agenda

    Science.gov (United States)

    Frey, Georgia C.; Stanish, Heidi I.; Temple, Viviene A.

    2008-01-01

    This review characterizes physical activity behavior in youth with intellectual disability (ID) and identifies limitations in the published research. Keyword searches were used to identify articles from MEDLINE, EBSCOhost Research Databases, Psych Articles, Health Source, and SPORT Discus, and ProQuest Dissertations and Theses up to June 2007.…

  3. The SHOCT domain: a widespread domain under-represented in model organisms.

    Directory of Open Access Journals (Sweden)

    Ruth Y Eberhardt

    Full Text Available We have identified a new protein domain, which we have named the SHOCT domain (Short C-terminal domain. This domain is widespread in bacteria with over a thousand examples. But we found it is missing from the most commonly studied model organisms, despite being present in closely related species. It's predominantly C-terminal location, co-occurrence with numerous other domains and short size is reminiscent of the Gram-positive anchor motif, however it is present in a much wider range of species. We suggest several hypotheses about the function of SHOCT, including oligomerisation and nucleic acid binding. Our initial experiments do not support its role as an oligomerisation domain.

  4. Relationships between widespread pain and thresholds pain tolerance on tender points in Portuguese women with fibromyalgia: impact on daily life.

    Directory of Open Access Journals (Sweden)

    Pablo Tomas-Carus

    2015-07-01

    Full Text Available Objectives: to establish a relationship between widespread pain subjectively perceived and threshold pain tolerance on tender points, and to determine whether there are differences in threshold pain tolerance on tender points between the upper and lower body, as well as between the dominant and non-dominant side, and whether these differences have an impact on the daily life of Portuguese women with fibromyalgia (FM. Material e Methods: thirty-one women with FM aged between 34 and 67 years volunteered for the study. Threshold pain tolerance was assessed at critical points using a digital algometer pressure; the widespread pain index (WPI was constructed by the addition of 19 painful body regions; and the impact on the daily life assessed by the Portuguese version of the Fibromyalgia Impact Questionnaire (FIQ, with individual interviews. Results: significant differences between the percentage of threshold pain tolerance of the whole body and the scales of widespread pain subjectively perceived were observed, showing that the widespread pain subjectively perceived by patients was between +25.9% and +27.5%. Also, significant differences between threshold pain tolerance of tender points located on the upper and lower body (1.9 ± 0.5 kg/cm2 vs. 2.6 ± 0.7 kg/cm2; respectively were observed. However, no significant differences were found between threshold pain tolerance of tender points located on dominant and non-dominant sides (2.1 ± 0.5 kg/cm2 e 2.1 ± 0.6 kg/cm2; respectively. Additionally, the analysis showed significant correlations between pain and patient`s daily life in: FIQ total score, physical function, feel good, job ability and fatigue. Conclusions: the women with FM show higher widespread pain subjectively perceived than threshold pain tolerance on tender points. Furthermore, the pain suffered by the patients with FM, especially that located on the upper body, either on the dominant or on the non-dominant side, has a negative

  5. An overview of research activities on materials for nuclear applications at the INL Safety, Tritium and Applied Research facility

    Energy Technology Data Exchange (ETDEWEB)

    Calderoni, P., E-mail: Pattrick.Calderoni@inl.gov [Fusion Safety Program, Idaho National Laboratory, PO Box 1625, Idaho Falls, ID 83415-7113 (United States); Sharpe, J.; Shimada, M.; Denny, B.; Pawelko, B.; Schuetz, S.; Longhurst, G. [Fusion Safety Program, Idaho National Laboratory, PO Box 1625, Idaho Falls, ID 83415-7113 (United States); Hatano, Y.; Hara, M. [Hydrogen Isotope Research Center, University of Toyama, Gofuku 3190, Toyama 930-8555 (Japan); Oya, Y. [Radioscience Research Laboratory, Faculty of Science, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka 422-8529 (Japan); Otsuka, T.; Katayama, K. [Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581 (Japan); Konishi, S.; Noborio, K.; Yamamoto, Y. [Institute of Advanced Energy, Kyoto University, Gokasho, Uji, Kyoto 611-0011 (Japan)

    2011-10-01

    The Safety, Tritium and Applied Research facility at the Idaho National Laboratory is a US Department of Energy National User Facility engaged in various aspects of materials research for nuclear applications related to fusion and advanced fission systems. Research activities are mainly focused on the interaction of tritium with materials, in particular plasma facing components, liquid breeders, high temperature coolants, fuel cladding, cooling and blanket structures and heat exchangers. Other activities include validation and verification experiments in support of the Fusion Safety Program, such as beryllium dust reactivity and dust transport in vacuum vessels, and support of Advanced Test Reactor irradiation experiments. This paper presents an overview of the programs engaged in the activities, which include the US-Japan TITAN collaboration, the US ITER program, the Next Generation Power Plant program and the tritium production program, and a presentation of ongoing experiments as well as a summary of recent results with emphasis on fusion relevant materials.

  6. An overview of research activities on materials for nuclear applications at the INL Safety, Tritium and Applied Research facility

    International Nuclear Information System (INIS)

    Calderoni, P.; Sharpe, J.; Shimada, M.; Denny, B.; Pawelko, B.; Schuetz, S.; Longhurst, G.; Hatano, Y.; Hara, M.; Oya, Y.; Otsuka, T.; Katayama, K.; Konishi, S.; Noborio, K.; Yamamoto, Y.

    2011-01-01

    The Safety, Tritium and Applied Research facility at the Idaho National Laboratory is a US Department of Energy National User Facility engaged in various aspects of materials research for nuclear applications related to fusion and advanced fission systems. Research activities are mainly focused on the interaction of tritium with materials, in particular plasma facing components, liquid breeders, high temperature coolants, fuel cladding, cooling and blanket structures and heat exchangers. Other activities include validation and verification experiments in support of the Fusion Safety Program, such as beryllium dust reactivity and dust transport in vacuum vessels, and support of Advanced Test Reactor irradiation experiments. This paper presents an overview of the programs engaged in the activities, which include the US-Japan TITAN collaboration, the US ITER program, the Next Generation Power Plant program and the tritium production program, and a presentation of ongoing experiments as well as a summary of recent results with emphasis on fusion relevant materials.

  7. Summary of activities of the Research Branch during 1981

    International Nuclear Information System (INIS)

    1982-07-01

    A general view of the work performed during 1981 by CNEA's Research Branch in basic and applied research is provided. The information includes the main activities and achievements in: 1) Physics Department: Tandar Project; Technical Assistance and Engineering; Experimental and Theoretical Nuclear Physics; Solid State Physics. 2) Reactor Chemistry Department: Chemical Control Division; Moderator and Coolant Physical-Chemistry Division; Radiation Chemistry Division. 3) Radiobiology Department: Radiation Pathology; Cellular Biology; Somatic Effects of the Ionizing Radiations; Genetics; Radiomicrobiology; Bioterium; Irradiation and Dosimetry Section, and, finally, in Biomathematics, Labelled Molecules and Radiochemistry. (M.E.L.) [es

  8. Recent Cooperative Research Activities of HDD and Flexible Media Transport Technologies in Japan

    Science.gov (United States)

    Ono, Kyosuke

    This paper presents the recent status of industry-university cooperative research activities in Japan on the mechatronics of information storage and input/output equipment. There are three research committees for promoting information exchange on technical problems and research topics of head-disk interface in hard disk drives (HDD), flexible media transport and image printing processes which are supported by the Japan Society of Mechanical Engineering (JSME), the Japanese Society of Tribologists (JAST) and the Japan Society of Precision Engineering (JSPE). For hard disk drive technology, the Storage Research Consortium (SRC) is supporting more than 40 research groups in various different universities to perform basic research for future HDD technology. The past and present statuses of these activities are introduced, particularly focusing on HDD and flexible media transport mechanisms.

  9. Widespread osteonecrosis of the foot in systemic lupus erythematosus: Radiographic and gross pathologic correlation

    Energy Technology Data Exchange (ETDEWEB)

    Resnick, D; Pineda, C; Trudell, D

    1985-01-01

    A patient with systemic lupus erythematosus required an amputation of the foot related to the presence of vascular disease and infection. Radiographs obtained prior to amputation revealed osteonecrosis in virtually every bone of the foot. Radiographic-pathologic correlation documented this widespread osseous involvement. Although ischemic necrosis of bone is a well-known feature of systemic lupus erythematosus, its localization in the small bones of the foot is rare.

  10. Widespread osteonecrosis of the foot in systemic lupus erythematosus: Radiographic and gross pathologic correlation

    International Nuclear Information System (INIS)

    Resnick, D.; Pineda, C.; Trudell, D.; California Univ., San Diego, La Jolla

    1985-01-01

    A patient with systemic lupus erythematosus required an amputation of the foot related to the presence of vascular disease and infection. Radiographs obtained prior to amputation revealed osteonecrosis in virtually every bone of the foot. Radiographic-pathologic correlation documented this widespread osseous involvement. Although ischemic necrosis of bone is a well-known feature of systemic lupus erythematosus, its localization in the small bones of the foot is rare. (orig.)

  11. Recent research and development activities on partitioning and transmutation of radioactive nuclides in Japan

    International Nuclear Information System (INIS)

    Minato, K.; Ikegami, T.; Inoue, T.

    2005-01-01

    In Japan, research and development activities for partitioning and transmutation (P and T) have been promoted under the OMEGA programme for more than 15 years. These activities were reviewed by the Atomic Energy Commission in Japan in 2000. In accordance with the results of the review, three institutes, the Japan Atomic Energy Research Institute (JAERI), the Japan Nuclear Cycle Development Institute (JNC) and the Central Research Institute of Electric Power Industry (CRIEPI), are continuing the research and development on the P and T technology. This report summarises the recent activities in Japan by these institutes. JAERI is engaging in the research and development on the Double-strata Fuel Cycle concept consisting of the partitioning process of the high-level waste and the dedicated transmutation cycle using the accelerator driven system (ADS) fuelled with the minor actinide (MA) nitride fuel. JNC and CRIEPI are engaging in the research and development on the P and T technology using commercialized fast reactors (FR), where JNC is mainly in charge of the MOX fuel and the aqueous reprocessing, while CRIEPI is mainly in charge of the metallic fuel and the dry reprocessing. The research and development activities on FR are organised under the Feasibility Study on Commercialized Fast Reactor Cycle Systems. (authors)

  12. Developments in Transnational Research Collaborations: Evidence from U.S. Higher-education Activity

    Directory of Open Access Journals (Sweden)

    Peter H Koehn

    2014-07-01

    Full Text Available In our knowledge-driven era, multiple and mutual benefits accrue from transnational research linkages. The article identifies important directions in transnational research collaborations involving U.S. universities revealed by key dimensions of 369 projects profiled on a U.S. higher-education association’s database. Project initiators, principal research fields, regional and country distributions, and the sources and amounts of funding for different types of transnational research activity are selected for analysis. The balanced total portfolio of reported current research projects by region suggests that U.S. university principal investigators increasingly recognize the value of collaborative knowledge generation in the Global South as well as in other OECD countries. The data also show concentrations in the distribution of transnational research projects by principal field of activity that could exacerbate intra-regional asymmetries. The multi-institutional data draw attention to the often unnoticed, but vital, role that higher-education institutions play in supporting transnational research endeavors that address issues of current and future global concern. The conclusion considers wider implications for higher-education involvement in transnational knowledge generation and calls for increased symmetry in collaborative research ventures.

  13. Clean Coal Program Research Activities

    Energy Technology Data Exchange (ETDEWEB)

    Larry Baxter; Eric Eddings; Thomas Fletcher; Kerry Kelly; JoAnn Lighty; Ronald Pugmire; Adel Sarofim; Geoffrey Silcox; Phillip Smith; Jeremy Thornock; Jost Wendt; Kevin Whitty

    2009-03-31

    Although remarkable progress has been made in developing technologies for the clean and efficient utilization of coal, the biggest challenge in the utilization of coal is still the protection of the environment. Specifically, electric utilities face increasingly stringent restriction on the emissions of NO{sub x} and SO{sub x}, new mercury emission standards, and mounting pressure for the mitigation of CO{sub 2} emissions, an environmental challenge that is greater than any they have previously faced. The Utah Clean Coal Program addressed issues related to innovations for existing power plants including retrofit technologies for carbon capture and sequestration (CCS) or green field plants with CCS. The Program focused on the following areas: simulation, mercury control, oxycoal combustion, gasification, sequestration, chemical looping combustion, materials investigations and student research experiences. The goal of this program was to begin to integrate the experimental and simulation activities and to partner with NETL researchers to integrate the Program's results with those at NETL, using simulation as the vehicle for integration and innovation. The investigators also committed to training students in coal utilization technology tuned to the environmental constraints that we face in the future; to this end the Program supported approximately 12 graduate students toward the completion of their graduate degree in addition to numerous undergraduate students. With the increased importance of coal for energy independence, training of graduate and undergraduate students in the development of new technologies is critical.

  14. High-speed research program systems analysis activities at Ames Research Center

    Science.gov (United States)

    Kidwell, George H.

    1992-01-01

    The Ames Systems Analysis Branch has been working to support the High Speed Research Program (HSRP) for nearly one year. Both the status of methodology development activities and the results of studies are presented whether completed or underway. The discussion involves the conceptual design synthesis program used for High Speed Civil Transport (HSCT) studies, ACSYNT (aircraft synthesis), and enhancements that have been made especially for HSRP. Some results are presented for one study that has been completed and two that are underway. These are the advanced controls integration study, the fuel cost impact study, and the oblique wing configuration evaluation that is part of a larger innovative concepts study.

  15. History of the bubble chamber and related active- and internal-target nuclear tracking detectors

    International Nuclear Information System (INIS)

    Becchetti, F.D.

    2015-01-01

    Donald Glaser, 1960 Nobel laureate in Physics, recently passed away (2013), as have many of his colleagues who were involved with the early development of bubble chambers at the University of Michigan. In this paper I will review those early years and the subsequent wide-spread application of active-target (AT) bubble chambers that dominated high-energy physics (HEP) research for over thirty years. Some of the related, but more modern nuclear tracking detectors being used in HEP, neutrino astrophysics and dark-matter searches also will be discussed

  16. Activities for extending the lifetime of MINT research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Bokhari, Adnan; Kassim, Mohammad Suhaimi [Malaysian Inst. for Nuclear Technology Research (MINT), Bangi, Kajang (Malaysia)

    1998-10-01

    MINT TRIGA Reactor is a 1-MW swimming pool nuclear reactor commissioned in June 1982. Since then, it has been used for research, isotope production, neutron activation, neutron radiography and manpower training. The total operating time till the end on September 1997 is 16968 hours with cumulative total energy release of 11188 MW-hours. After more than fifteen years of successful operation, some deterioration in components and associated systems has been observed. This paper describes some of the activities carried out to increase the lifetime and to reduce the shutdown time of the reactor. (author)

  17. Assessing research activity and capacity of community-based organizations: development and pilot testing of an instrument.

    Science.gov (United States)

    Humphries, Debbie L; Carroll-Scott, Amy; Mitchell, Leif; Tian, Terry; Choudhury, Shonali; Fiellin, David A

    2014-01-01

    Although awareness of the importance of the research capacity of community-based organizations (CBOs) is growing, a uniform framework of the research capacity domains within CBOs has not yet been developed. To develop a framework and instrument (the Community REsearch Activity assessment Tool [CREAT]) for assessing the research activity and capacity of CBOs that incorporates awareness of the different data collection and analysis priorities of CBOs. We conducted a review of existing tools for assessing research capacity to identify key capacity domains. Instrument items were developed through an iterative process with CBO representatives and community researchers. The CREAT was then pilot tested with 30 CBOs. The four primary domains of the CREAT framework include 1) organizational support for research, 2) generalizable experiences, 3) research specific experiences, and 4) funding. Organizations reported a high prevalence of activities in the research-specific experiences domain, including conducting literature reviews (70%), use of research terminology (83%), and primary data collection (100%). Respondents see research findings as important to improve program and service delivery, and to seek funds for new programs and services. Funders, board members, and policymakers are the most important dissemination audiences. The work reported herein advances the field of CBO research capacity by developing a systematic framework for assessing research activity and capacity relevant to the work of CBOs, and by developing and piloting an instrument to assess activity in these domains.

  18. Position-dependent termination and widespread obligatory frameshifting in Euplotes translation

    Energy Technology Data Exchange (ETDEWEB)

    Lobanov, Alexei V.; Heaphy, Stephen M.; Turanov, Anton A.; Gerashchenko, Maxim V.; Pucciarelli, Sandra; Devaraj, Raghul R.; Xie, Fang; Petyuk, Vladislav A.; Smith, Richard D.; Klobutcher, Lawrence A.; Atkins, John F.; Miceli, Cristina; Hatfield, Dolph L.; Baranov, Pavel V.; Gladyshev, Vadim N.

    2016-11-21

    The ribosome can change its reading frame during translation in a process known as programmed ribosomal frameshifting. These rare events are supported by complex mRNA signals. However, we found that the ciliates Euplotes crassus and Euplotes focardii exhibit widespread frameshifting at stop codons. 47 different codons preceding stop signals resulted in either +1 or +2 frameshifts, and +1 frameshifting at AAA was the most frequent. The frameshifts showed unusual plasticity and rapid evolution, and had little influence on translation rates. The proximity of a stop codon to the 3' mRNA end, rather than its occurrence or sequence context, appeared to designate termination. Thus, a ‘stop codon’ is not a sufficient signal for translation termination, and the default function of stop codons in Euplotes is frameshifting, whereas termination is specific to certain mRNA positions and probably requires additional factors.

  19. Future of the Learning Activities in Teenage School: Content, Methods, and Forms

    Directory of Open Access Journals (Sweden)

    Vorontsov A.B.

    2015-11-01

    Full Text Available the early 1990s their scientific research results have been formed in the educational system and began to be used in general primary school. However, when the widespread use of developmental education in elementary school, further studies on the age possibilities of adolescents and the content of their education have not been completed. Targeted research was organized again under the leadership of B.D. Elkonin only in 2000. Designing of teenage school in the framework of the principles and ideology of this system started at the same time at the Psychological Institute of the Russian Academy of Education and many other educational institutions. The article presents the hypothetical ideas about the content, forms and methods of organization of educational process in the second stage of schooling. Particular attention is paid to the fate of the educational activity in teenage school, as well as methods and forms of organization of other activities in the adolescent school.

  20. Review of research institute library activity through the contributed papers. The case of the Japan Atomic Energy Research Institute Library

    International Nuclear Information System (INIS)

    Ikeda, Kiyoshi; Habara, Tadashi; Ishikawa, Masashi; Itabashi, Keizo; Yonezawa, Minoru

    2007-03-01

    The Japan Atomic Energy Research Institute (JAERI) Library had contributed 312 papers through the library activities in half-century. We made the bibliography of these papers as well as categorized them into general', 'library functions', 'management and promotion of research results' and 'international exchange of information' and explained them under the four categories. A subject index, an author index of these papers and chronology of JAERI library activities were also compiled for reference. (author)

  1. Eleven years of net network research activity - inr contributions

    International Nuclear Information System (INIS)

    Deaconu, V.; Ionita, I.; Meleg, T.; Deaconu, M.; Truta, C.; Oncioiu, G.

    2013-01-01

    The European Network on Neutron Techniques Standardization for Structural Integrity (NeT) was established in 2002, grouping institutions from industry, research and academic media. Coordinated by the European Commission.s Joint Research Centre, the main mission of this network is to develop experimental and numerical techniques and standards for the reliable characterisation of residual stresses in structural welds. Each problem is tackled by creating a dedicated Task Group which manages measurement and modelling round robin studies and undertakes a thorough analysis and interpretation of the results. Over forty institutions are active NeT partners, their specific involvement and contributions being summarised in this paper. The Institute for Nuclear Research Pitesti (INR) is one of NeT founders and its contribution is related to numerical modelling, specimen analysis, material characterisation, data analysis or SANS support. This is also emphasised throughout this paper, together with the specific NeT research topics presentation. (authors)

  2. Flipping the Audience Script: An Activity That Integrates Research and Audience Analysis

    Science.gov (United States)

    Lam, Chris; Hannah, Mark A.

    2016-01-01

    This article describes a flipped classroom activity that requires students to integrate research and audience analysis. The activity uses Twitter as a data source. In the activity, students identify a sample, collect customer tweets, and analyze the language of the tweets in an effort to construct knowledge about an audience's values, needs, and…

  3. Amphibian Chytrid Fungus in Madagascar neither Shows Widespread Presence nor Signs of Certain Establishment.

    Science.gov (United States)

    Kolby, Jonathan E; Skerratt, Lee F

    2015-01-01

    The global spread of amphibian chytrid fungus (Batrachochytrium dendrobatidis, Bd) is associated with amphibian mass mortality, population decline, and extinction. Over the past decade, concern has been expressed for the potential introduction of Bd to Madagascar, a global hotspot of amphibian biodiversity. Following years without detection, widespread Bd presence in Madagascar has now been reported (Bletz et al. 2015a), raising international conservation concern. Before reacting to this finding with a significant management response, the accuracy and context of the data warrant cautious review. Re-examination of a 10-year dataset together with results from more recent surveillance (Kolby et al. 2015) does not yet demonstrate widespread Bd presence. Detection of Bd at "positive" locations in Madagascar has been inconsistent for unknown reasons. Whether Bd is established in Madagascar (i.e. populations are self-sustaining) or instead requires continued introduction to persist also remains uncertain. The deployment of emergency conservation rescue initiatives is expected to target areas where the distribution of Bd and the risk of chytridiomycosis endangering amphibians is believed to overlap. Thus, erroneous description of Bd presence would misdirect limited conservation resources. Standardized surveillance and confirmatory surveys are now imperative to reliably characterize the distribution, potential spread, virulence and overall risk of Bd to amphibians in Madagascar.

  4. Amphibian Chytrid Fungus in Madagascar neither Shows Widespread Presence nor Signs of Certain Establishment.

    Directory of Open Access Journals (Sweden)

    Jonathan E Kolby

    Full Text Available The global spread of amphibian chytrid fungus (Batrachochytrium dendrobatidis, Bd is associated with amphibian mass mortality, population decline, and extinction. Over the past decade, concern has been expressed for the potential introduction of Bd to Madagascar, a global hotspot of amphibian biodiversity. Following years without detection, widespread Bd presence in Madagascar has now been reported (Bletz et al. 2015a, raising international conservation concern. Before reacting to this finding with a significant management response, the accuracy and context of the data warrant cautious review. Re-examination of a 10-year dataset together with results from more recent surveillance (Kolby et al. 2015 does not yet demonstrate widespread Bd presence. Detection of Bd at "positive" locations in Madagascar has been inconsistent for unknown reasons. Whether Bd is established in Madagascar (i.e. populations are self-sustaining or instead requires continued introduction to persist also remains uncertain. The deployment of emergency conservation rescue initiatives is expected to target areas where the distribution of Bd and the risk of chytridiomycosis endangering amphibians is believed to overlap. Thus, erroneous description of Bd presence would misdirect limited conservation resources. Standardized surveillance and confirmatory surveys are now imperative to reliably characterize the distribution, potential spread, virulence and overall risk of Bd to amphibians in Madagascar.

  5. Drug-eluting stents: from bench-top to clinical research

    NARCIS (Netherlands)

    Basalus, Mounir Welson Zakhary

    2013-01-01

    The development of drug-eluting stents (DES) has improved the invasive treatment of obstructive coronary artery disease by reducing both, restenosis rate and need for reinterventions. This success resulted in a widespread utilization of DES in clinical practice and entailed many clinical research

  6. CRISPR/Cas9 for cancer research and therapy.

    Science.gov (United States)

    Zhan, Tianzuo; Rindtorff, Niklas; Betge, Johannes; Ebert, Matthias P; Boutros, Michael

    2018-04-16

    CRISPR/Cas9 has become a powerful method for making changes to the genome of many organisms. First discovered in bacteria as part of an adaptive immune system, CRISPR/Cas9 and modified versions have found a widespread use to engineer genomes and to activate or to repress the expression of genes. As such, CRISPR/Cas9 promises to accelerate cancer research by providing an efficient technology to dissect mechanisms of tumorigenesis, identify targets for drug development, and possibly arm cells for cell-based therapies. Here, we review current applications of the CRISPR/Cas9 technology for cancer research and therapy. We describe novel Cas9 variants and how they are used in functional genomics to discover novel cancer-specific vulnerabilities. Furthermore, we highlight the impact of CRISPR/Cas9 in generating organoid and mouse models of cancer. Finally, we provide an overview of the first clinical trials that apply CRISPR/Cas9 as a therapeutic approach against cancer. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

  7. Research for the energy turnaround. Phase transitions actively shape. Contributions

    International Nuclear Information System (INIS)

    Szczepanski, Petra; Wunschick, Franziska; Martin, Niklas

    2015-01-01

    The Annual Conference 2014 of the Renewable Energy Research Association was held in Berlin on 6 and 7 November 2014. This book documents the contributions of the conference on research for the energy turnaround, phase transitions actively shape. After an introduction and two contributions to the political framework, the contributions to the economic phases of the energy transition, the phase of the current turn, the phases of social energy revolution, the stages of heat turnaround (Waermewende), and the stages of the mobility turn deal with the stages of development of the energy system. Finally, the Research Association Renewable Energy is briefly presented. [de

  8. KFK annual report on research and development activities in 1988

    International Nuclear Information System (INIS)

    1989-01-01

    This annual report on R and D activities in the year 1988 is published by the Karlsruhe Nuclear Research Centre in compliance with section 13.4 of the corporate statutes. The presentation adopts the arrangement of the subjects and items as given in the R and D programme planning of the centre. The reports given by the various institutes and main departments have been collected in their relevant subject groups, with reference being given to the reporting source. Summary reports of activities are obtainable direct from the relevant institutes or main departments. The annual report reviews the progress achieved in every of the R and D projects listed in the KfK programms, and the material is arranged so as to facilitate a comparison between planned and achieved purposes, and to show activities within their entire context, as the R and D programm frequently distributes research tasks for a common project to various institutes. Detailed accounts can be found in the numerous scientific-technical publications listed, or in the KfK status reports. In compliance with the underlying programme budgeting report, the annual report, upon decision by the competent bodies, also presents a summary report of R and D activities in 1988. (orig.) [de

  9. Health researchers in Alberta: an exploratory comparison of defining characteristics and knowledge translation activities

    Directory of Open Access Journals (Sweden)

    Birdsell Judy M

    2007-01-01

    Full Text Available Abstract Background Canadian funding agencies are no longer content to support research that solely advances scientific knowledge, and key directives are now in place to promote research transfer to policy- and decision-makers. Therefore, it is necessary to improve our understanding of how researchers are trained and supported to facilitate knowledge translation activities. In this study, we investigated differences in health researcher characteristics and knowledge translation activities. Methods Our sample consisted of 240 health researchers from three Alberta universities. Respondents were classified by research domain [basic (n = 72 or applied (n = 168] and faculty [medical school (n = 128 or other health science (n = 112]. We examined our findings using Mode I and Mode II archetypes of knowledge production, which allowed us to consider the scholarly and social contexts of knowledge production and translation. Results Differences among health researcher professional characteristics were not statistically significant. There was a significant gender difference in the applied researcher faculty group, which was predominantly female (p p p = .01; Mode II, p p = .025 and number of publications (medical school > other faculties; p = .004. There was an interaction effect for research domain and faculty group for number of publications (p = .01, in that applied researchers in medical faculties published more than their peers in other faculty groups. Conclusion Our findings illustrate important differences between health researchers and provide beginning insights into their professional characteristics and engagement in Mode I and Mode II activities. A future study designed to examine these dimensions in greater detail, including potential covariates across more varied institutions, would yield richer insights and enable an examination of relative influences, needs and costs of each mode of activity.

  10. EVIDENCE FOR WIDESPREAD ACTIVE GALACTIC NUCLEUS ACTIVITY AMONG MASSIVE QUIESCENT GALAXIES AT z ∼ 2

    International Nuclear Information System (INIS)

    Olsen, Karen P.; Rasmussen, Jesper; Toft, Sune; Zirm, Andrew W.

    2013-01-01

    We quantify the presence of active galactic nuclei (AGNs) in a mass-complete (M * > 5 × 10 10 M ☉ ) sample of 123 star-forming and quiescent galaxies at 1.5 ≤ z ≤ 2.5, using X-ray data from the 4 Ms Chandra Deep Field-South (CDF-S) survey. 41% ± 7% of the galaxies are detected directly in X-rays, 22% ± 5% with rest-frame 0.5-8 keV luminosities consistent with hosting luminous AGNs (L 0.5-8keV > 3 × 10 42 erg s –1 ). The latter fraction is similar for star-forming and quiescent galaxies, and does not depend on galaxy stellar mass, suggesting that perhaps luminous AGNs are triggered by external effects such as mergers. We detect significant mean X-ray signals in stacked images for both the individually non-detected star-forming and quiescent galaxies, with spectra consistent with star formation only and/or a low-luminosity AGN in both cases. Comparing star formation rates inferred from the 2-10 keV luminosities to those from rest-frame IR+UV emission, we find evidence for an X-ray excess indicative of low-luminosity AGNs. Among the quiescent galaxies, the excess suggests that as many as 70%-100% of these contain low- or high-luminosity AGNs, while the corresponding fraction is lower among star-forming galaxies (43%-65%). Our discovery of the ubiquity of AGNs in massive, quiescent z ∼ 2 galaxies provides observational support for the importance of AGNs in impeding star formation during galaxy evolution.

  11. Why combine diet and physical activity in the same international research society?

    Directory of Open Access Journals (Sweden)

    Baranowski Tom

    2004-02-01

    Full Text Available Abstract Research in diet and physical activity in the U.S. started in very different traditions, with behavioral science input being uneven in their development. Investigators and policy makers in Europe have recognized the complementarity of diet and physical activity and incorporated them both under the label Public Health Nutrition. Joining these disciplines internationally offers the opportunity to benefit all, since the problems addressed are human, not specific to any one country. In regard to why combine diet and physical activity, at the biological level, there is reason to believe that diet and physical activity working in concert can remodel physiological structures and processes toward healthful ends. The diet and physical activity behaviors themselves vary in characteristics and are similar in others. The behavioral science components of these two disciplines face similar problems, and can learn from the advances made by the other, in the areas of measurement, correlates and intervention. By working together, knowledge will be enhanced from uncovering complementary and interactive relationships between diet and physical activity, and in relation to disease risks, that may result in designing more effective and efficient interventions and policies. Since the behavioral sciences are at a disadvantage in comparison to the biological sciences in terms of scientific advances and thereby capturing the popular imagination for solutions to health problems, we must redouble our efforts to enhance funding for behavioral research in regard to diet and physical activity and to make the research advances necessary to prevent the medicalizing of essentially social and behavioral problems. Nutrition and physical activity should most effectively do this together.

  12. Transparency in the reporting of in vivo pre-clinical pain research: The relevance and implications of the ARRIVE (Animal Research: Reporting In Vivo Experiments) guidelines.

    Science.gov (United States)

    Rice, Andrew S C; Morland, Rosemary; Huang, Wenlong; Currie, Gillian L; Sena, Emily S; Macleod, Malcolm R

    2017-12-29

    Clear reporting of research is crucial to the scientific process. Poorly designed and reported studies are damaging not only to the efforts of individual researchers, but also to science as a whole. Standardised reporting methods, such as those already established for reporting randomised clinical trials, have led to improved study design and facilitated the processes of clinical systematic review and meta-analysis. Such standards were lacking in the pre-clinical field until the development of the ARRIVE (Animal Research: Reporting In Vivo Experiments) guidelines. These were prompted following a survey which highlighted a widespread lack of robust and consistent reporting of pre-clinical in vivo research, with reports frequently omitting basic information required for study replication and quality assessment. The resulting twenty item checklist in ARRIVE covers all aspects of experimental design with particular emphasis on bias reduction and methodological transparency. Influential publishers and research funders have already adopted ARRIVE. Further dissemination and acknowledgement of the importance of these guidelines is vital to their widespread implementation. Conclusions and implications Wide implementation of the ARRIVE guidelines for reporting of in vivo preclinical research, especially pain research, are essential for a much needed increased transparency and quality in publishing such research. ARRIVE will also positively influence improvements in experimental design and quality, assist the conduct of accurate replication studies of important new findings and facilitate meta-analyses of preclinical research.

  13. Research Activity in Computational Physics utilizing High Performance Computing: Co-authorship Network Analysis

    Science.gov (United States)

    Ahn, Sul-Ah; Jung, Youngim

    2016-10-01

    The research activities of the computational physicists utilizing high performance computing are analyzed by bibliometirc approaches. This study aims at providing the computational physicists utilizing high-performance computing and policy planners with useful bibliometric results for an assessment of research activities. In order to achieve this purpose, we carried out a co-authorship network analysis of journal articles to assess the research activities of researchers for high-performance computational physics as a case study. For this study, we used journal articles of the Scopus database from Elsevier covering the time period of 2004-2013. We extracted the author rank in the physics field utilizing high-performance computing by the number of papers published during ten years from 2004. Finally, we drew the co-authorship network for 45 top-authors and their coauthors, and described some features of the co-authorship network in relation to the author rank. Suggestions for further studies are discussed.

  14. Federal Plan for Cyber Security and Information Assurance Research and Development

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — Powerful personal computers, high-bandwidth and wireless networking technologies, and the widespread use of the Internet have transformed stand-alone computing...

  15. Advancement in Perfluoroalkyl Research Hampered by Analytical Challenges

    NARCIS (Netherlands)

    Martin, J.W.; Kannan, K.; Berger, U.; de Voogt, P.; Field, J.; Giesy, J.P.; Harner, T.; Muir, D.C.G.; Scott, B.; Kaiser, M.; Jarnberg, U.; Jones, K.C.; Mabury, S.A.; Schroeder, H.; Simcik, M.; Sottani, C.; Van Bavel, B.; Karrman, A.; Lindstrom, G.; Van Leeuwen, S.

    2004-01-01

    The growing concern over these organohalogens, some of which have been found in human blood and appear to be widespread in the environment, led researchers to gather in Hamburg, Germany, in 2003 to evaluate the current state of methods to analyze for the organic contaminants. Jonathan Martin of the

  16. Antioxidant and antibacterial activities of Cladophora glomerata (L ...

    African Journals Online (AJOL)

    Cladophora is one of the largest filamentous green-algal genus and has a widespread distribution in Caspian Sea Coast. This study aimed at assaying the antimicrobial and antioxidant activities of Cladophora glomerata in South of Caspian sea. The antioxidant activity of the extract was investigated, including the total ...

  17. Computer Science Research Institute 2004 annual report of activities.

    Energy Technology Data Exchange (ETDEWEB)

    DeLap, Barbara J.; Womble, David Eugene; Ceballos, Deanna Rose

    2006-03-01

    This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2004 to December 31, 2004. During this period the CSRI hosted 166 visitors representing 81 universities, companies and laboratories. Of these 65 were summer students or faculty. The CSRI partially sponsored 2 workshops and also organized and was the primary host for 4 workshops. These 4 CSRI sponsored workshops had 140 participants--74 from universities, companies and laboratories, and 66 from Sandia. Finally, the CSRI sponsored 14 long-term collaborative research projects and 5 Sabbaticals.

  18. Computer Science Research Institute 2003 annual report of activities.

    Energy Technology Data Exchange (ETDEWEB)

    DeLap, Barbara J.; Womble, David Eugene; Ceballos, Deanna Rose

    2006-03-01

    This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2003 to December 31, 2003. During this period the CSRI hosted 164 visitors representing 78 universities, companies and laboratories. Of these 78 were summer students or faculty members. The CSRI partially sponsored 5 workshops and also organized and was the primary host for 3 workshops. These 3 CSRI sponsored workshops had 178 participants--137 from universities, companies and laboratories, and 41 from Sandia. Finally, the CSRI sponsored 18 long-term collaborative research projects and 5 Sabbaticals.

  19. Computer Science Research Institute 2005 annual report of activities.

    Energy Technology Data Exchange (ETDEWEB)

    Watts, Bernadette M.; Collis, Samuel Scott; Ceballos, Deanna Rose; Womble, David Eugene

    2008-04-01

    This report summarizes the activities of the Computer Science Research Institute (CSRI) at Sandia National Laboratories during the period January 1, 2005 to December 31, 2005. During this period, the CSRI hosted 182 visitors representing 83 universities, companies and laboratories. Of these, 60 were summer students or faculty. The CSRI partially sponsored 2 workshops and also organized and was the primary host for 3 workshops. These 3 CSRI sponsored workshops had 105 participants, 78 from universities, companies and laboratories, and 27 from Sandia. Finally, the CSRI sponsored 12 long-term collaborative research projects and 3 Sabbaticals.

  20. Institut fuer Materialforschung. Research and development activities in 1994

    International Nuclear Information System (INIS)

    1995-01-01

    The IMF consists of three institutes with different tasks: IMF I works mainly on the development of metals, nonmetals and composite materials and on problems concerning the structure and properties of interfaces and protective layers. IMF II works on component reliablility, failure mechanisms and damage analysis. IMF III works on problems of process engineering in the production of ceramic powders and ceramic, metallic and polymeric microstructures, as well as on the design of nuclear components and the optimisation of corrosive materials. The IMF supports the research activities of Karlsruhe Research Center, especially in nuclear fusion research, microsystems engineering, nuclear safety, superconductivity, and low-pollution and low-waste processes. Materials and strength problems are investigated for future fusion reactors, high-performance microsystems, and safety problems in nuclear engineering. (orig./MM) [de

  1. Utilization and facility of neutron activation analysis in HANARO research reactor

    International Nuclear Information System (INIS)

    Chung, Y.S.; Chung, Y.J.; Moon, J.H.

    1998-01-01

    The facilities of neutron activation analysis within a multi-purpose research reactor (HANARO) are described and the main applications of Neutron activation analysis (NAA) in Korea are reviewed. The sample irradiation tube, automatic and manual pneumatic transfer system, are installed at three irradiation holes. One irradiation hole is lined with a cadmium tube for epithermal-nal NAA. The performance of the NAA facility was examined to identify the characteristics of tube transfer system, irradiation sites and polyethylene irradiation capsule. The available thermal neutron flux with each irradiation site are in the range of 3.9x10 13 -1.6x10 14 n/cm 2 ·s and cadmium ratios are 15-250. Neutron activation analysis has been applied in the trace component analysis of nuclear, geological, biological, environmental and high purity materials and various polymers for research and development. Analytical services and the latest analytical results are summarized. (author)

  2. Ten years research activities in Earth observation at the Cyprus University of Technology

    Science.gov (United States)

    Hadjimitsis, Diofantos G.; Themistocleous, Kyriacos; Agapiou, Athos; Mamouri, Rodanthi; Nisantzi, Argyro; Papoutsa, Christiana; Tzouvaras, Marios; Neoclous, Kyriacos; Mettas, Christodoulos; Michaelides, Silas

    2017-09-01

    This paper presents the achievements for the last 10 years of the Remote Sensing and Geo-Environment Laboratory of the Cyprus University of Technology in the Earth observation through the ERATOSTHENES Research Centre. Over the past 10 years, the Centre has secured competitive research funding from various sources, such as the European Commission, the Cyprus Research Promotion Foundation, as well as industrial partners, having participated either as a coordinator or as a partner in more than 60 research projects. The research activities of the Centre encompass remote sensing and GIS applications in the fields of Cultural Heritage, Agriculture, Water Resource Management, Environment, Infrastructure, Marine Spatial Planning, Atmospheric, Air Pollution and Coastal Applications, Natural Resource Management and Hazard Assessment. The aim of this paper is to map the existing activities and identify the future trends and goals of the Eratosthenes Research Centre for the next 15 years.

  3. Sustainable Transportation Systems Research Group: Ongoing and Past Activities

    OpenAIRE

    Gkritza, Konstantina "Nadia"; Hurtado, Davis Chacon; Gkartzonikas, Christos; Ke, Yue; Losada, Lisa L

    2017-01-01

    This presentation describes the ongoing and past activities of the Sustainable Transportation Systems Research (STSR) group at Purdue University (https://engineering.purdue.edu/STSRG). The STSR group aims to achieve green, safe, efficient, and equitable transportation systems by studying and modeling transportation externalities, using state of the art statistical, econometric, and economic analysis tools.

  4. Phytophthora capsici - Loss of Heterozygosity (LOH): A Widespread Mechanism for Rapid Adaptation (7th Annual SFAF Meeting, 2012)

    Energy Technology Data Exchange (ETDEWEB)

    Mudge, Joanne

    2012-06-01

    Joanne Mudge on "Phytophthora capsici - Loss of Heterozygosity (LOH): A Widespread Mechanism for Rapid Mutation" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

  5. COE-INES report on research and education activities 2003-2004

    International Nuclear Information System (INIS)

    2007-03-01

    Research and education activities during 2003-2004 on innovative nuclear energy systems to solve safety, radioactive waste and proliferation problems simultaneously, were reported. CANDLE (Constant Axial shape of Neutron flux, nuclide densities and power shape During Life of Energy producing reactor) burnup core was proposed for small fast reactors, while design and relevant basic technologies of lead-bismuth cooled and supercritical carbon dioxide cooled fast reactors were studied as well as innovative hydrogen energy systems. Basic research on micro/nano-scale separation/transmutation of actinide nuclides and long-life fission products was conducted. Research on nuclear energy and social involvement was also initiated. (T. Tanaka)

  6. COE-INES report on research and education activities 2005-2006

    International Nuclear Information System (INIS)

    2007-03-01

    Research and education activities during 2005-2006 on innovative nuclear energy systems to solve safety, radioactive waste and proliferation problems simultaneously, were reported. CANDLE (Constant Axial shape of Neutron flux, nuclide densities and power shape During Life of Energy producing reactor), lead-bismuth cooled fast reactors, small long-life reactors and water-cooled thorium breeding reactors were studied as innovative nuclear reactors. Experimental study of hydrogen system with carbon dioxide zero emission was progressed. Basic research on micro-nano-scale separation/transmutation of actinide nuclides and long-life fission products was conducted. Research on nuclear energy and social involvement was also conducted. (J.P.N.)

  7. COE-INES report on research and education activities. Final report

    International Nuclear Information System (INIS)

    2008-03-01

    Research and education activities on innovative nuclear energy systems to solve safety, radioactive waste and proliferation problems simultaneously, were summarized as a final report of COE-INES program. CANDLE (Constant Axial shape of Neutron flux, nuclide densities and power shape During Life of Energy producing reactor), lead-bismuth cooled fast reactors, small long-life reactors and water-cooled thorium breeding reactors were studies as innovative nuclear reactors. Experimental study of hydrogen system with carbon dioxide zero emission was progressed. Basic research on micro/nano-scale separation/transmutation of actinide nuclides and long-life fission products was conducted. Research on nuclear energy and social involvement was also conducted. (J.P.N.)

  8. Thermal Tolerance in Widespread and Tropical Drosophila Species: Does Phenotypic Plasticity Increase with Latitude?

    DEFF Research Database (Denmark)

    Overgaard, Johannes; Kristensen, Torsten Nygård; Mitchell, Katherin A

    2011-01-01

    The distribution of insects can often be related to variation in their response to thermal extremes, which in turn may reflect differences in plastic responses or innate variation in resistance. Species with widespread distributions are expected to have evolved higher levels of plasticity than....... The results do not support the hypothesis that widely distributed species have larger phenotypic plasticity for thermal tolerance limits, and Drosophila species distributions are therefore more closely linked to differences in innate thermal tolerance limits....

  9. Antimicrobial activity of fluoride and its in vivo importance: identification of research questions.

    Science.gov (United States)

    Van Loveren, C

    2001-01-01

    This manuscript discusses the antimicrobial activity of fluoride and its in vivo importance in order to identify research questions. There is a lot of information on mechanisms by which fluoride may interfere with bacterial metabolism and dental plaque acidogenicity. The antimicrobial activity of fluoride products is enhanced when fluoride is associated with antimicrobial cations like Sn(2+) and amine. It is not clear whether the antimicrobial mechanisms of fluoride are operating in vivo or even to what extent antimicrobial activity can contribute to caries prevention. This latter question may be the most important one in research. Copyright 2001 S. Karger AG, Basel.

  10. A Cloud-based Infrastructure and Architecture for Environmental System Research

    Science.gov (United States)

    Wang, D.; Wei, Y.; Shankar, M.; Quigley, J.; Wilson, B. E.

    2016-12-01

    The present availability of high-capacity networks, low-cost computers and storage devices, and the widespread adoption of hardware virtualization and service-oriented architecture provide a great opportunity to enable data and computing infrastructure sharing between closely related research activities. By taking advantage of these approaches, along with the world-class high computing and data infrastructure located at Oak Ridge National Laboratory, a cloud-based infrastructure and architecture has been developed to efficiently deliver essential data and informatics service and utilities to the environmental system research community, and will provide unique capabilities that allows terrestrial ecosystem research projects to share their software utilities (tools), data and even data submission workflow in a straightforward fashion. The infrastructure will minimize large disruptions from current project-based data submission workflows for better acceptances from existing projects, since many ecosystem research projects already have their own requirements or preferences for data submission and collection. The infrastructure will eliminate scalability problems with current project silos by provide unified data services and infrastructure. The Infrastructure consists of two key components (1) a collection of configurable virtual computing environments and user management systems that expedite data submission and collection from environmental system research community, and (2) scalable data management services and system, originated and development by ORNL data centers.

  11. Fifteen year's research activities of the INSS Institute of Nuclear Technology and future policy

    International Nuclear Information System (INIS)

    Kimura, Itsuro

    2008-01-01

    Fifteen years have passed since the Institute of Nuclear Safety System, Incorporated (INSS) was founded. This paper reviews the research activities of the Institute of Nuclear Technology in INSS over that time and proposes a policy for future research. First, a chronological table shows the major milestones over the past fifteen years. Notable events include the following. The head office was moved to Mihama-cho where laboratories and experimental facilities were installed; the Institute signed an agreement with the Kansai Electric Power Co., Inc. (KEPCO) on assistance for the preparedness of nuclear emergency; it assisted KEPCO to investigate the causes of the accident at its Mihama Nuclear Power Station Unit 3 and subsequently established the Nuclear Power Plant Aging Research Center, it began providing information on adverse events occurred at nuclear power plants in the world to Japanese electric utilities that own PWRs; it supported the Energy Research and Development Centralization Plan of Fukui Prefecture, and it embarked on a project to develop the Fukui regional cluster in the Fukui and Kinki area under the government's program for aging management of nuclear power plants. The fifteen years of research activities are shown for each research group and for each research project, and then important achievements of the major research projects are described. Finally, the status of research papers published in external Journals and in INSS over the past fifteen years is illustrated and the number of patents acquired during this period is presented. We evaluated our research activities over the fifteen years and reviewed them according to seven items under a future research policy. The plans include the enhancement of system engineering-based research efforts as the name of this Institute implies, and committing ourselves to forward-looking and creative research program focusing on not only from analysis', but also on 'synthesis'. A suitable approach to safety

  12. Public open space, physical activity, urban design and public health: Concepts, methods and research agenda.

    Science.gov (United States)

    Koohsari, Mohammad Javad; Mavoa, Suzanne; Villanueva, Karen; Sugiyama, Takemi; Badland, Hannah; Kaczynski, Andrew T; Owen, Neville; Giles-Corti, Billie

    2015-05-01

    Public open spaces such as parks and green spaces are key built environment elements within neighbourhoods for encouraging a variety of physical activity behaviours. Over the past decade, there has been a burgeoning number of active living research studies examining the influence of public open space on physical activity. However, the evidence shows mixed associations between different aspects of public open space (e.g., proximity, size, quality) and physical activity. These inconsistencies hinder the development of specific evidence-based guidelines for urban designers and policy-makers for (re)designing public open space to encourage physical activity. This paper aims to move this research agenda forward, by identifying key conceptual and methodological issues that may contribute to inconsistencies in research examining relations between public open space and physical activity. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Drought's legacy: multiyear hydraulic deterioration underlies widespread aspen forest die-off and portends increased future risk.

    Science.gov (United States)

    Anderegg, William R L; Plavcová, Lenka; Anderegg, Leander D L; Hacke, Uwe G; Berry, Joseph A; Field, Christopher B

    2013-04-01

    Forest mortality constitutes a major uncertainty in projections of climate impacts on terrestrial ecosystems and carbon-cycle feedbacks. Recent drought-induced, widespread forest die-offs highlight that climate change could accelerate forest mortality with its diverse and potentially severe consequences for the global carbon cycle, ecosystem services, and biodiversity. How trees die during drought over multiple years remains largely unknown and precludes mechanistic modeling and prediction of forest die-off with climate change. Here, we examine the physiological basis of a recent multiyear widespread die-off of trembling aspen (Populus tremuloides) across much of western North America. Using observations from both native trees while they are dying and a rainfall exclusion experiment on mature trees, we measure hydraulic performance over multiple seasons and years and assess pathways of accumulated hydraulic damage. We test whether accumulated hydraulic damage can predict the probability of tree survival over 2 years. We find that hydraulic damage persisted and increased in dying trees over multiple years and exhibited few signs of repair. This accumulated hydraulic deterioration is largely mediated by increased vulnerability to cavitation, a process known as cavitation fatigue. Furthermore, this hydraulic damage predicts the probability of interyear stem mortality. Contrary to the expectation that surviving trees have weathered severe drought, the hydraulic deterioration demonstrated here reveals that surviving regions of these forests are actually more vulnerable to future droughts due to accumulated xylem damage. As the most widespread tree species in North America, increasing vulnerability to drought in these forests has important ramifications for ecosystem stability, biodiversity, and ecosystem carbon balance. Our results provide a foundation for incorporating accumulated drought impacts into climate-vegetation models. Finally, our findings highlight the

  14. Physical activity parenting measurement and research: Challenges, explanations, and solutions

    Science.gov (United States)

    Physical activity (PA) parenting research has proliferated over the past decade, with findings verifying the influential role that parents play in children's emerging PA behaviors. This knowledge, however, has not translated into effective family-based PA interventions. During a preconference worksh...

  15. Widespread ectopic expression of olfactory receptor genes

    Directory of Open Access Journals (Sweden)

    Yanai Itai

    2006-05-01

    Full Text Available Abstract Background Olfactory receptors (ORs are the largest gene family in the human genome. Although they are expected to be expressed specifically in olfactory tissues, some ectopic expression has been reported, with special emphasis on sperm and testis. The present study systematically explores the expression patterns of OR genes in a large number of tissues and assesses the potential functional implication of such ectopic expression. Results We analyzed the expression of hundreds of human and mouse OR transcripts, via EST and microarray data, in several dozens of human and mouse tissues. Different tissues had specific, relatively small OR gene subsets which had particularly high expression levels. In testis, average expression was not particularly high, and very few highly expressed genes were found, none corresponding to ORs previously implicated in sperm chemotaxis. Higher expression levels were more common for genes with a non-OR genomic neighbor. Importantly, no correlation in expression levels was detected for human-mouse orthologous pairs. Also, no significant difference in expression levels was seen between intact and pseudogenized ORs, except for the pseudogenes of subfamily 7E which has undergone a human-specific expansion. Conclusion The OR superfamily as a whole, show widespread, locus-dependent and heterogeneous expression, in agreement with a neutral or near neutral evolutionary model for transcription control. These results cannot reject the possibility that small OR subsets might play functional roles in different tissues, however considerable care should be exerted when offering a functional interpretation for ectopic OR expression based only on transcription information.

  16. Research and development on activation analysis at the Thailand Institute of Nuclear Technology

    International Nuclear Information System (INIS)

    Laoharojanaphand, S.; Dharmavanij, W.; Busamongkol, A.; Pareepart, R.; Wimolwattanapun, W.; Chantarachot, W.

    2008-01-01

    Research and development in activation analysis at the Thailand Institute of Nuclear Technology has been carried out over 40 years. The main activation source is from the TRIGA type research reactor TRR1/M1. Average in-core flux is around 10 13 n x cm -2 x s -1 . Experience on the analysis of various kind of samples range from environmental field especially air particulate, ores, rocks and soil for natural resources exploration as well as industrial applications. Elemental composition in silk thread, silk cocoon and silk products from the royal silk project are one of the research work done incorporation with the Queen Sirikit Institute of Sericulture. Food items are also another topic of interest to our research team. (author)

  17. Current status of research and related activities in NAA application

    International Nuclear Information System (INIS)

    Ab Khalik bin Haji Wood

    1999-01-01

    Current activities of Analytical Chemistry Group of MINT (Malaysia Institute for Nuclear Technology Research) laboratory for elemental analysis of trace amounts in environmental samples such as air particulate matter (on air filter), soils/sediments, water, flora/fauna, oil sludge/waste sludge, and tailing/blasting slag and others, utilizing particularly NAA (Neutron Activation Analysis) method are reviewed. The laboratory participates in the IAEA-organized Interlaboratory Comparison Studies to ensure the analytical system. Other activities include analytical chemistry services with ICP-mass spectrometry and GC/GCMS to compliment the NAA and, moreover, air and marine pollution studies with participation in the UNDP/RCA/IAEA project. (S. Ohno)

  18. Use of research reactors for neutron activation analysis. Report of an advisory group meeting

    International Nuclear Information System (INIS)

    2001-04-01

    Neutron activation analysis (NAA) is an analytical technique based on the measurement of characteristic radiation from radionuclides formed directly or indirectly by neutron irradiation of the material of interest. In the last three decades, neutron activation analysis has been found to be extremely useful in the determination of trace and minor elements in many disciplines. These include environmental analysis applications, nutritional and health related studies, geological as well as material sciences. The most suitable source of neutrons for NAA is a research reactor. There are several application fields in which NAA has a superior position compared to other analytical methods, and there are good prospects in developing countries for long term growth. Therefore, the IAEA is making concerted efforts to promote neutron activation analysis and at the same time to assist developing Member States in better utilization of their research reactors. The purpose of the meeting was to discuss the benefits and the role of NAA in applications and research areas that may contribute towards improving utilization of research reactors. The participants focused on five specific topics: (1) Current trends in NAA; (2) The role of NAA compared to other methods of chemical analysis; (3) How to increase the number of NAA users through interaction with industries, research institutes, universities and medical institutions; (4) How to reduce costs and to maintain quality and reliability; (5) NAA using low power research reactors. Neutron activation analysis in its various forms is still active and there are good prospects in developing countries for long-term growth. This can be achieved by a more effective use of existing irradiation and counting facilities, a better end-user focus, and perhaps marginal improvements in equipment and techniques. Therefore, it is recommended that the Member States provide financial and other assistance to enhance the effectiveness of their laboratories

  19. Assessing worldwide research activity on probiotics in pediatrics using Scopus database: 1994-2014.

    Science.gov (United States)

    Sweileh, Waleed M; Shraim, Naser Y; Al-Jabi, Samah W; Sawalha, Ansam F; Rahhal, Belal; Khayyat, Rasha A; Zyoud, Sa'ed H

    2016-01-01

    A wide variety of probiotic products has been introduced into the market in the past decade. Research trends and activity on probiotics help understand how these products were evolved and their potential future role in medicine. The objective of this study was to assess the research activity on probiotics in pediatrics using bibliometric indicators and network visualization. Original and review articles on probiotics in pediatrics published worldwide were retrieved from SciVerse, Scopus (1994-2014) and analyzed. VOSviewer was used for network visualization. The total number of documents published on probiotics in pediatrics was 2817. Research activity on probiotics in pediatrics showed approximately 90- fold increase during the study period. Approximately 22 % of published articles originated from USA and has the greatest share, however, Finland ranked first when data were stratified by population or income. The most productive institution in this field was Turku University in Finland with 82 (2.91 %) articles. Half of the prolific authors were also from Finland. Most of the published research activity appeared in Journal of Pediatric Gastroenterology and Nutrition. Most frequently encountered title terms include nutrition, infant formula, necrotizing enetrocolitis, allergy, and diarrhea. The total number of citations for the retreived documents documents was 70991, and the average citation per article was 25.20. Interest in probiotic research and its potential benefits in pediatric ailments is relatively recent but significantly increasing. Bibliometric analysis can be used as an indicator of the importance and growth of probiotic use in pediatrics.

  20. Measuring presenteeism: which questionnaire to use in physical activity research?

    Science.gov (United States)

    Brown, Helen Elizabeth; Burton, Nicola; Gilson, Nicholas David; Brown, Wendy

    2014-02-01

    An emerging area of interest in workplace health is presenteeism; the measurable extent to which physical or psychosocial symptoms, conditions and disease adversely affect the work productivity of those who choose to remain at work. Given established links between presenteeism and health, and health and physical activity, presenteeism could be an important outcome in workplace physical activity research. This study provides a narrative review of questionnaires for use in such research. Eight self-report measures of presenteeism were identified. Information regarding development, constructs measured and psychometric properties was extracted from relevant articles. Questionnaires were largely self-administered, had 4-44 items, and recall periods ranging from 1 week to 1 year. Items were identified as assessing work performance, physical tolerance, psychological well-being and social or role functioning. Samples used to test questionnaires were predominantly American male employees, with an age range of 30-59 years. All instruments had undergone psychometric assessment, most commonly discriminant and construct validity. Based on instrument characteristics, the range of conceptual foci covered and acceptable measurement properties, the Health and Work Questionnaire, Work Ability Index, and Work Limitations Questionnaire are suggested as most suitable for further exploring the relationship between physical activity and presenteeism.

  1. In vitro Antibacterial Activities of the Marine Macroalgae\\" Laurencia Snyderiae\\" and \\"Sargassum Angustifolium\\" Against Human Pathogens

    Directory of Open Access Journals (Sweden)

    behrouz Derakhshesh

    2011-04-01

    Full Text Available Background: Nowadays widespread applications of antibiotics caused to create resistant microorganisms and increased additive antibiotic resistance in all over the world. Thus, researches linked to investigate new antimicrobial agents that are produced in natural way have great significance to achieve new pharmaceutics resources. Based on many accomplished researches, some macroalgae have found to show noticeable antimicrobial and antifungal activities. Methods: In this research antimicrobial activity of organic extracts of the macroalgae "Laurencia snyderiae" and Sargassum angustifolium (which has been collected from coasts of Boushehr port was tested against 3 Gram- positive bacteria Streptococous mutans, Streptococous salivaris and Streptococous sanguis as well as 4 Gram- negative bacteria Salmonella typhi, Proteus vulgaris, Shigella flexniu and Micrococos luteus. Extraction was carried out using maceration method, methanol and chloroform extracts was obtained. Antimicrobial activities of the final extracts was tested using two methods agar disk diffusion method and serial tube dilution method (in order to determine Minimum Inhibitory Concentration (MIC. Results: Results of bioassay showed the tested macroalgae exhibited the highest antibacterial activity against Gram- negative bacteria, S. typhi and Gram- negative bacteria M. Luteus exhibited the highest resistant against algal extracts. Conclusion: red alga L. snyderiae exhibited higher antibacterial activity than brown alga S. angustifolium against tested bacteria strains.

  2. Utilization and facility of neutron activation analysis in HANARO research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Y S; Chung, Y J; Moon, J H [Korea Atomic Energy Research Institute, P.O.Box 105 Yusong, 305-600, Taejon (Korea, Republic of)

    1998-07-01

    The facilities of neutron activation analysis within a multi-purpose research reactor (HANARO) are described and the main applications of Neutron activation analysis (NAA) in Korea are reviewed. The sample irradiation tube, automatic and manual pneumatic transfer system, are installed at three irradiation holes. One irradiation hole is lined with a cadmium tube for epithermal-nal NAA. The performance of the NAA facility was examined to identify the characteristics of tube transfer system, irradiation sites and polyethylene irradiation capsule. The available thermal neutron flux with each irradiation site are in the range of 3.9x10{sup 13}-1.6x10{sup 14} n/cm{sup 2}{center_dot}s and cadmium ratios are 15-250. Neutron activation analysis has been applied in the trace component analysis of nuclear, geological, biological, environmental and high purity materials and various polymers for research and development. Analytical services and the latest analytical results are summarized. (author)

  3. Chronic Widespread Pain after Motor Vehicle Collision Typically Occurs via Immediate Development and Non-Recovery: Results of an Emergency Department-Based Cohort Study

    Science.gov (United States)

    JunMei, Hu; Andrey V, Bortsov; Lauren, Ballina; Danielle C, Orrey; Robert A, Swor; David, Peak; Jeffrey, Jones; Niels, Rathlev; David C, Lee; Robert, Domeier; Phyllis, Hendry; Blair A, Parry; Samuel A, McLean

    2016-01-01

    Motor vehicle collision (MVC) can trigger chronic widespread pain (CWP) development in vulnerable individuals. Whether such CWP typically develops via the evolution of pain from regional to widespread or via the early development of widespread pain with non-recovery is currently unknown. We evaluated the trajectory of CWP development (American College of Rheumatology criteria) among 948 European-American individuals who presented to the emergency department (ED) for care in the early aftermath of MVC. Pain extent was assessed in the ED and 6 weeks, 6 months, and 1 year after MVC on 100%, 91%, 89%, and 91% of participants, respectively. Individuals who reported prior CWP at the time of ED evaluation (n = 53) were excluded. Trajectory modeling identified a two-group solution as optimal, with the Bayes Factor value (138) indicating strong model selection. Linear solution plots supported a non-recovery model. While the number of body regions with pain in the non-CWP group steadily declined, the number of body regions with pain in the CWP trajectory group (192/895, 22%) remained relatively constant over time. These data support the hypothesis that individuals who develop CWP after MVC develop widespread pain in the early aftermath of MVC which does not remit. PMID:26808013

  4. Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint Loading.

    Science.gov (United States)

    Pazzinatto, Marcella Ferraz; de Oliveira Silva, Danilo; Barton, Christian; Rathleff, Michael Skovdal; Briani, Ronaldo Valdir; de Azevedo, Fábio Mícolis

    2016-10-01

    Compare pressure pain thresholds (PPTs) at the knee and a site remote to the knee in female adults with patellofemoral pain (PFP) to pain-free controls before and after a patellofemoral joint (PFJ) loading protocol designed to aggravate symptoms. Cross-sectional study SETTING: Participants were recruited via advertisements in fitness centers, public places for physical activity and universities. Thirty-eight females with patellofemoral pain, and 33 female pain-free controls. All participant performed a novel PFJ loading protocol involving stair negotiation with an extra load equivalent 35% of body mass. PPTs and current knee pain (measured on a visual analogue scale) was assessed before and after the loading protocol. PPTs were measured at four sites around the knee and one remote site on the upper contralateral limb. Females with PFP demonstrated significantly lower PPTs locally and remote to the knee, both before and after the PFJ loading protocol when compared to control group. Following the loading protocol, PPTs at knee were significantly reduced by 0.54 kgf (95%CI = 0.33; 0.74) for quadriceps tendon, 0.38 kgf (95%CI = 0.14; 0.63) for medial patella, and 0.44 kgf (95%CI = 0.18; 0.69) for lateral patella. No significant change in PPT remote to the knee was observed - 0.10 kgf (95%CI = -0.04; 0.24). Female adults with PFP have local and widespread hyperalgesia compared to pain free controls. A novel loading protocol designed to aggravate symptoms, lowers the PPTs locally at the knee but has no effect on PPT on the upper contralateral limb. This suggests widespread hyperalgesia is not affected by acute symptom aggravation. © 2016 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  5. Accelerator and Fusion Research Division: summary of activities, 1983

    International Nuclear Information System (INIS)

    1984-08-01

    The activities described in this summary of the Accelerator and Fusion Research Division are diverse, yet united by a common theme: it is our purpose to explore technologically advanced techniques for the production, acceleration, or transport of high-energy beams. These beams may be the heavy ions of interest in nuclear science, medical research, and heavy-ion inertial-confinement fusion; they may be beams of deuterium and hydrogen atoms, used to heat and confine plasmas in magnetic fusion experiments; they may be ultrahigh-energy protons for the next high-energy hadron collider; or they may be high-brilliance, highly coherent, picosecond pulses of synchrotron radiation

  6. Utilization of the Dalat Research Reactor for Radioisotope Production, Neutron Activation Analysis, Research and Training

    International Nuclear Information System (INIS)

    Nguyen Nhi Dien; Duong Van Dong; Cao Dong Vu; Nguyen Xuan Hai

    2013-01-01

    The Dalat Nuclear Research Reactor (DNRR) is a 500 kW pool type reactor loaded with a mixed core of HEU (36% enrichment) and LEU (19.75% enrichment) fuel assemblies. The reactor is used as a neutron source for the purposes of radioisotopes production, neutron activation analysis, basic and applied research and training. The reactor is operated mainly in continuous runs of 108 hours for cycles of 3–4 weeks for the above mentioned purposes. The current status of safety, operation and utilization of the reactor is given and some aspects for improvement of commercial products and services of the DNRR are also discussed in this paper. (author)

  7. U.S. energy research and development: Declining investment, increasing need, and the feasibility of expansion

    International Nuclear Information System (INIS)

    Nemet, Gregory F.; Kammen, Daniel M.

    2007-01-01

    Investment in energy research and development in the U.S. is declining despite calls for an enhancement of the nation's capacity for innovation to address environmental, geopolitical, and macroeconomic concerns. We examine investments in research and development in the energy sector, and observe broad-based declines in funding since the mid-1990s. The large reductions in investment by the private sector should be a particular area of concern for policy makers. Multiple measures of patenting activity reveal widespread declines in innovative activity that are correlated with research and development (R and D) investment-notably in the environmentally significant wind and solar areas. Trends in venture capital investment and fuel cell innovation are two promising cases that run counter to the overall trends in the sector. We draw on prior work on the optimal level of energy R and D to identify a range of values which would be adequate to address energy-related concerns. Comparing simple scenarios based on this range to past public R and D programs and industry investment data indicates that a five to ten-fold increase in energy R and D investment is both warranted and feasible

  8. Averting Uncertainty: A Practical Guide to Physical Activity Research in Australian Schools

    Science.gov (United States)

    Rachele, Jerome N.; Cuddihy, Thomas F.; Washington, Tracy L.; McPhail, Steven M.

    2013-01-01

    Preventative health has become central to contemporary health care, identifying youth physical activity as a key factor in determining health and functioning. Schools offer a unique research setting due to distinctive methodological circumstances. However, school-based researchers face several obstacles in their endeavour to complete successful…

  9. Understanding physical activity in spinal cord injury rehabilitation: translating and communicating research through stories.

    Science.gov (United States)

    Smith, Brett; Papathomas, Anthony; Martin Ginis, Kathleen A; Latimer-Cheung, Amy E

    2013-01-01

    The purpose of this article is to develop an evidence-based resource for knowing and communicating the complexities involved for both males and females in implementing and sustaining a physically active lifestyle shortly after spinal cord injury (SCI). Synthesizing a set of qualitative and quantitative studies with over 500 spinal cord injured people, the article represents research utilizing the genre of ethnographic creative non-fiction. This genre of representation holds enormous potential for researchers in terms of disseminating their findings to diverse audiences beyond the academy, and having real impact. The ethnographic creative non-fictions show together for the first time the barriers, determinants, benefits, trajectories, emotions, fears, preferred methods and messengers for delivering important physical activity information to men and women with a SCI. The article contributes to knowledge by showing the embodied complexities involved when in rehabilitation for both males and females in implementing and sustaining a physically active lifestyle shortly after SCI. It also makes a contribution to practice by providing researchers, health care professionals and disability user-groups with a theory and evidence based resource to assist in informing, teaching and enabling people living with SCI to initiate and maintain a physically active lifestyle. Stories may be a highly effective tool to communicate with and to influence spinal cord injured people's activity. The findings of this research showed the many benefits and barriers to developing and sustaining a physically active lifestyle shortly after spinal cord injury. The preferred methods and messengers for delivering physical activity information as well as the activity types, intensities and durations of physical activity for men and women were also shown. Within rehabilitation, spinal cord injured people need to be offered accessible knowledge about how to implement and sustain a physically active

  10. Current status of neutron activation analysis in HANARO Research Reactor

    International Nuclear Information System (INIS)

    Chung, Yong Sam; Moon, Jong Hwa; Sohn, Jae Min

    2003-01-01

    The facilities for neutron activation analysis in the HANARO (Hi-flux Advanced Neutron Application Research Reactor) are described and the main applications of NAA (Neutron Activation Analysis) are reviewed. The sample irradiation tube, automatic and manual pneumatic transfer system were installed at three irradiation holes of HANARO at the end of 1995. The performance of the NAA facility was examined to identify the characteristics of the tube transfer system, irradiation sites and custom-made polyethylene irradiation capsule. The available thermal neutron fluxes at irradiation sites are in the range of 3 x 10 13 - 1 x 10 14 n/cm 2 ·s and cadmium ratios are in 15 - 250. For an automatic sample changer for gamma-ray counting, a domestic product was designed and manufactured. An integrated computer program (Labview) to analyse the content was developed. In 2001, PGNAA (Prompt Gamma Neutron Activation Analysis) facility has been installed using a diffracted neutron beam of ST1. NAA has been applied in the trace component analysis of nuclear, geological, biological, environmental and high purity materials, and various polymers for research and development. The improvement of analytical procedures and establishment of an analytical quality control and assurance system were studied. Applied research and development for the environment, industry and human health by NAA and its standardization were carried out. For the application of the KOLAS (Korea Laboratory Accreditation Scheme), evaluation of measurement uncertainty and proficiency testing of reference materials were performed. Also to verify the reliability and to validate analytical results, intercomparison studies between laboratories were carried out. (author)

  11. Current status of neutron activation analysis in HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yong Sam; Moon, Jong Hwa; Sohn, Jae Min [Korea Atomic Energy Research Institute, Daejeon (Korea)

    2003-03-01

    The facilities for neutron activation analysis in the HANARO (Hi-flux Advanced Neutron Application Research Reactor) are described and the main applications of NAA (Neutron Activation Analysis) are reviewed. The sample irradiation tube, automatic and manual pneumatic transfer system were installed at three irradiation holes of HANARO at the end of 1995. The performance of the NAA facility was examined to identify the characteristics of the tube transfer system, irradiation sites and custom-made polyethylene irradiation capsule. The available thermal neutron fluxes at irradiation sites are in the range of 3 x 10{sup 13} - 1 x 10{sup 14} n/cm{sup 2}{center_dot}s and cadmium ratios are in 15 - 250. For an automatic sample changer for gamma-ray counting, a domestic product was designed and manufactured. An integrated computer program (Labview) to analyse the content was developed. In 2001, PGNAA (Prompt Gamma Neutron Activation Analysis) facility has been installed using a diffracted neutron beam of ST1. NAA has been applied in the trace component analysis of nuclear, geological, biological, environmental and high purity materials, and various polymers for research and development. The improvement of analytical procedures and establishment of an analytical quality control and assurance system were studied. Applied research and development for the environment, industry and human health by NAA and its standardization were carried out. For the application of the KOLAS (Korea Laboratory Accreditation Scheme), evaluation of measurement uncertainty and proficiency testing of reference materials were performed. Also to verify the reliability and to validate analytical results, intercomparison studies between laboratories were carried out. (author)

  12. Weathering-related origin of widespread monazite in S-type granites

    Energy Technology Data Exchange (ETDEWEB)

    Sawka, W N; Banfield, J F; Chappell, B W

    1986-01-01

    The S-type granite suites comprising more than a quarter of the extensively developed granites in the Lachlan Fold Belt, Australia, contain monazite which may be related to the chemical weathering of the sedimentary source rocks. We report a process whereby chemical weathering fixes mobile rare-earth elements (REE) in hydrous phosphate phases such as florencite and rhabdophane. This material contains up to 50 wt.% LREE and occurs as very small particles (approx. 3 ..mu..m). Dehydration of these hydrous REE phases during anatexis directly yields monazite. The low solubility of phosphorus in S-type granite melts inhibits dissolution of both monazite and apatite. Refractory monazite may be thus entrained and transported in S-type granites in a manner similar to processes resulting in inherited zircon. Since both Th and the light REE are major components in monazite, materials containing this minute phase may be of widespread geochemical significance in both granites and metamorphic rocks.

  13. Research in the fields of radiochemistry and activation analysis using the LENA TRIGA nuclear plant

    International Nuclear Information System (INIS)

    Maxia, V.; Meloni, S.; Stella, R.; Brandone, A.

    1972-01-01

    In the past two years most of the research effort at the Radiochemistry Laboratory and National Research Council Centre for Radiochemistry and Activation Analysis has been devoted to research and development of activation analysis using the TRIGA Mark II LENA reactor of the University of Pavia. Pile neutrons have been used both in steady state and pulse mode, in the determination of oxygen in non ferrous materials. Neutron activation has been applied to the determination of some atmospheric particulate pollutants. Another field, in which activation analysis has been applied, is forensic research. Methods have been developed for the determination of antimony, barium and copper in gunpowder residues. By using inorganic materials such as molybdenum dibromide, zinc ferrocyanide and cadmium metal in granular form it was possible to set up simple chemical procedures in the activation analysis of trace amounts of noble metals in metallic matrices (high purity nickel and copper), geochemical materials (rocks and meteorites) and biological materials (orchard leaves). Neutron activation analysis was also used to investigate on the extraction of the platinum group metals from iodide and thiocyanate solutions at low concentrations

  14. Regulatory activities and their research and development support in the CSSR

    International Nuclear Information System (INIS)

    Klik, F.; Kriz, Z.

    1977-01-01

    According to the existing laws the Czechoslovak Atomic Energy Commission (CSAEC) is authorized to regulate the Czechoslovak nuclear activities with respect to the nuclear safety, waste management and accountability and control of nuclear materials. Its activity with respect to nuclear safety consists mainly of: preparation of safety code of practices supplemented by safety guides for nuclear facilities, assessment of nuclear safety and issuing of binding opinion on nuclear safety for licensing of nuclear facilities, inspection of nuclear safety during construction and operation of nuclear facilities. The first part of the paper deals with the regulatory implementation. This covers the first stage specified by the construction and operation of research reactors only, the second stage specified by the design, construction, commissioning and operation of the first prototype nuclear power plant and the present stage specified by the construction and commissioning of a number of industrially developed nuclear power reactors. The present stage of regulatory implementation is described in detail. This covers the development of regulatory documentation such as safety code of practices and safety guides and the main safety requirements included in the existing safety code of practices for the siting, design and operation of nuclear power plants equipped with pressure water reactors. Then the general licensing procedures and organization including the structure and contents of safety documentation required for the licensing of siting, construction and operation of nuclear power plants is also described. The paper deals also with the inspection practices applied during construction, commissioning and operation of nuclear power plant in order to verify that the licensing conditions and requirements are fulfilled. The paper gives also some basic information about coordination of CSAEC nuclear safety regulatory activity with the regulatory activities of other governmental bodies

  15. AINSE's role in tertiary sector applied nuclear research

    International Nuclear Information System (INIS)

    Cooper, R.

    2001-01-01

    The Australian Institute of Nuclear Science and Engineering (AINSE) is a collaboration between the Universities and the Australian Nuclear Science and Technology Organisation (ANSTO). Its aim is to foster research and training in areas associated with the applications of Nuclear Science and allied techniques. AINSE is now into the fifth decade of this unique association and in 2001 can claim the active membership of thirty-six of the publicly funded Universities in Australia plus the University of Auckland and its NZ government partner the Institute for Geological and Nuclear Sciences (IGNS). The widespread membership has brought with it a breadth of research areas and the traditional domains of fundamental nuclear science and allied engineering have found that they are now the stable platforms from which are launched environmental, archaeological, biomedical and novel-materials science. ANSTO's fifth decade will see the replacement of HIFAR with a state of the art research reactor that will bring biological applications to a sharper focus. A new accelerator-mass spectrometer will be commissioned during 2002 and is funded, in part, by a $1 M RIEF grant which itself recognises the quality and track record of all AINSE members' research. It will significantly assist a wide range of dating applications and also provide support to ion beam analysis (IBA) experiments. AINSE will continue to aid community collaboration with its conferences, workshops and participation in national conferences such as the AIP Congress, Vacuum Society, etc. On the international scene it is actively participating in major conferences to be held in Australia. The winter school is a venture into the undergraduate sphere

  16. Linking ecosystem scale vegetation change to shifts in carbon and water cycling: the consequences of widespread piñon mortality in the Southwest

    Energy Technology Data Exchange (ETDEWEB)

    Litvak, Marcy Ellen [University of New Mexico

    2012-10-01

    The southwestern United States experienced an extended drought from 1999-2002 which led to widespread coniferous tree mortality. Piñon-juniper (PJ) woodlands, which occupy 24 million ha throughout the Southwest, were extremely vulnerable to this drought. An abrupt die-off of 40 to 95% of piñon pine (Pinus edulis) and 2-25% of juniper (Juniperus monosperma) across 1.5 million ha triggered rapid and extensive changes in the structure of PJ woodlands with potentially large, yet unknown, consequences for ecosystem services and feedbacks between the carbon cycle and climate system. Given the spatial extent of PJ woodlands (3rd largest biome in the US) and climatic predictions of increased frequency and intensity of drought in the region, it is crucial to understand the consequences of these disturbances on regional carbon and energy dynamics, biogeochemical processes and atmospheric CO2. The overall objective of our research was to quantify what impact widespread mortality of piñon trees has for carbon and water cycling in PJ woodlands. Our specific objectives for this proposal were: 1) Quantify the carbon, water and energy exchange trajectory after mortality in PJ woodlands; 2) Determine the mechanisms controlling the response and recovery of ecosystem production and respiration processes following large-scale piñon mortality; 3) Use the relationships we measure between ecosystem structure and function PJ woodlands recover from mortality to scale the results of our study up to the regional scale.

  17. Cumulative Risk Assessment: Overview of Agency Guidance, Practice and Current Major Research Activities

    Science.gov (United States)

    Powerpoint presentation that includes the EPA's definition of CRA, relevant publications already in existence, the CRA Guidelines effort, science issues where research is still needed, program office practices related to CRA, and EPA research activities.

  18. A Course-Based Research Experience: How Benefits Change with Increased Investment in Instructional Time

    Science.gov (United States)

    Shaffer, Christopher D.; Alvarez, Consuelo J.; Bednarski, April E.; Dunbar, David; Goodman, Anya L.; Reinke, Catherine; Rosenwald, Anne G.; Wolyniak, Michael J.; Bailey, Cheryl; Barnard, Daron; Bazinet, Christopher; Beach, Dale L.; Bedard, James E. J.; Bhalla, Satish; Braverman, John; Burg, Martin; Chandrasekaran, Vidya; Chung, Hui-Min; Clase, Kari; DeJong, Randall J.; DiAngelo, Justin R.; Du, Chunguang; Eckdahl, Todd T.; Eisler, Heather; Emerson, Julia A.; Frary, Amy; Frohlich, Donald; Gosser, Yuying; Govind, Shubha; Haberman, Adam; Hark, Amy T.; Hauser, Charles; Hoogewerf, Arlene; Hoopes, Laura L. M.; Howell, Carina E.; Johnson, Diana; Jones, Christopher J.; Kadlec, Lisa; Kaehler, Marian; Key, S. Catherine Silver; Kleinschmit, Adam; Kokan, Nighat P.; Kopp, Olga; Kuleck, Gary; Leatherman, Judith; Lopilato, Jane; MacKinnon, Christy; Martinez-Cruzado, Juan Carlos; McNeil, Gerard; Mel, Stephanie; Mistry, Hemlata; Nagengast, Alexis; Overvoorde, Paul; Paetkau, Don W.; Parrish, Susan; Peterson, Celeste N.; Preuss, Mary; Reed, Laura K.; Revie, Dennis; Robic, Srebrenka; Roecklein-Canfield, Jennifer; Rubin, Michael R.; Saville, Kenneth; Schroeder, Stephanie; Sharif, Karim; Shaw, Mary; Skuse, Gary; Smith, Christopher D.; Smith, Mary A.; Smith, Sheryl T.; Spana, Eric; Spratt, Mary; Sreenivasan, Aparna; Stamm, Joyce; Szauter, Paul; Thompson, Jeffrey S.; Wawersik, Matthew; Youngblom, James; Zhou, Leming; Mardis, Elaine R.; Buhler, Jeremy; Leung, Wilson; Lopatto, David; Elgin, Sarah C. R.

    2014-01-01

    There is widespread agreement that science, technology, engineering, and mathematics programs should provide undergraduates with research experience. Practical issues and limited resources, however, make this a challenge. We have developed a bioinformatics project that provides a course-based research experience for students at a diverse group of…

  19. Widespread use and frequent detection of neonicotinoid insecticides in wetlands of Canada's Prairie Pothole Region.

    Science.gov (United States)

    Main, Anson R; Headley, John V; Peru, Kerry M; Michel, Nicole L; Cessna, Allan J; Morrissey, Christy A

    2014-01-01

    Neonicotinoids currently dominate the insecticide market as seed treatments on Canada's major Prairie crops (e.g., canola). The potential impact to ecologically significant wetlands in this dominantly agro-environment has largely been overlooked while the distribution of use, incidence and level of contamination remains unreported. We modelled the spatial distribution of neonicotinoid use across the three Prairie Provinces in combination with temporal assessments of water and sediment concentrations in wetlands to measure four active ingredients (clothianidin, thiamethoxam, imidacloprid and acetamiprid). From 2009 to 2012, neonicotinoid use was increasing; by 2012, applications covered an estimated ∼11 million hectares (44% of Prairie cropland) with >216,000 kg of active ingredients. Thiamethoxam, followed by clothianidin, were the dominant seed treatments by mass and area. Areas of high neonicotinoid use were identified as high density canola or soybean production. Water sampled four times from 136 wetlands (spring, summer, fall 2012 and spring 2013) across four rural municipalities in Saskatchewan similarly revealed clothianidin and thiamethoxam in the majority of samples. In spring 2012 prior to seeding, 36% of wetlands contained at least one neonicotinoid. Detections increased to 62% in summer 2012, declined to 16% in fall, and increased to 91% the following spring 2013 after ice-off. Peak concentrations were recorded during summer 2012 for both thiamethoxam (range: Wetlands situated in barley, canola and oat fields consistently contained higher mean concentrations of neonicotinoids than in grasslands, but no individual crop singularly influenced overall detections or concentrations. Distribution maps indicate neonicotinoid use is increasing and becoming more widespread with concerns for environmental loading, while frequently detected neonicotinoid concentrations in Prairie wetlands suggest high persistence and transport into wetlands.

  20. Widespread abnormalities of radiocolloid distribution in patients with mucopolysaccharidoses

    International Nuclear Information System (INIS)

    Klingensmith, W.C. III; Eikman, E.A.; Maumenee, I.; Wagner, H.N. Jr.

    1975-01-01

    Mucopolysaccharidoses (MPS) are inherited disorders of lysosomal enzymes. We have examined the sites of accumulation of intravenously injected /sup 99m/Tc-sulfur colloid in order to assess the regional distribution of phagocytic function in ten patients with MPS: three with Type I (Hurler), five with Type II (Hunter), one with Type III (Sanfilippo), and one with Type VI (Maroteaux-Lamy). Increased lung uptake was observed in 22 of 40 studies (55 percent) on the five patients with MPS Type II but in none of the 38 studies on patients with other MPS types. All MPS patients had diffuse recticuloendothelial (RE) marrow hypoplasia, despite normal or nearly normal hematocrits and hemoglobin levels, suggesting dissociation of the phagocytic and erythropoietic elements of the marrow. The eight patients with MPS Types I and II all had hepatomegaly and increased splenic uptake. Seven of these patients also had splenomegaly. The two patients with MPS Types III and VI did not have hepatosplenomegaly. These studies indicate that the lysosomal enzymic defect of MPS results in widespread abnormalities of the distribution of phagocytic function in the liver, spleen, bone marrow, and probably the lung as well

  1. Assessing biological invasions in European Seas: Biological traits of the most widespread non-indigenous species

    Science.gov (United States)

    Cardeccia, Alice; Marchini, Agnese; Occhipinti-Ambrogi, Anna; Galil, Bella; Gollasch, Stephan; Minchin, Dan; Narščius, Aleksas; Olenin, Sergej; Ojaveer, Henn

    2018-02-01

    The biological traits of the sixty-eight most widespread multicellular non-indigenous species (MWNIS) in European Seas: Baltic Sea, Western European Margin of the Atlantic Ocean and the Mediterranean Sea were examined. Data for nine biological traits was analyzed, and a total of 41 separate categories were used to describe the biological and ecological functions of these NIS. Our findings show that high dispersal ability, high reproductive rate and ecological generalization are the biological traits commonly associated with MWNIS. The functional groups that describe most of the 68 MWNIS are: photoautotrophic, zoobenthic (both sessile and motile) and nektonic predatory species. However, these 'most widespread' species comprise a wide range of taxa and biological trait profiles; thereby a clear "identikit of a perfect invader" for marine and brackish environments is difficult to define. Some traits, for example: "life form", "feeding method" and "mobility", feature multiple behaviours and strategies. Even species introduced by a single pathway, e.g. vessels, feature diverse biological trait profiles. MWNIS likely to impact community organization, structure and diversity are often associated with brackish environments. For many traits ("life form", "sociability", "reproductive type", "reproductive frequency", "haploid and diploid dispersal" and "mobility"), the categories mostly expressed by the impact-causing MWNIS do not differ substantially from the whole set of MWNIS.

  2. Progress report on neutron activation analysis at Dalat Nuclear Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Tuan, Nguyen Ngoc [Nuclear Research Institute, Dalat (Viet Nam)

    2003-03-01

    Neutron Activation Analysis (NAA) is one of most powerful techniques for the simultaneous multi-elements analysis. This technique has been studied and applied to analyze major, minor and trace elements in Geological, Biological and Environmental samples at Dalat Nuclear Research Reactor. At the sixth Workshop, February 8-11, 1999, Yojakarta, Indonesia we had a report on Current Status of Neutron Activation Analysis using Dalat Nuclear Research Reactor. Another report on Neutron Activation Analysis at the Dalat Nuclear Research Reactor also was presented at the seventh Workshop in Taejon, Korea from November 20-24, 2000. So in this report, we would like to present the results obtained of the application of NAA at NRI for one year as follows: (1) Determination of the concentrations of noble, rare earth, uranium, thorium and other elements in Geological samples according to requirement of clients particularly the geologists, who want to find out the mineral resources. (2) The analysis of concentration of radionuclides and nutrient elements in foodstuffs to attend the program on Asian Reference Man. (3) The evaluation of the contents of trace elements in crude oil and basement rock samples to determine original source of the oil. (4) Determination of the elemental composition of airborne particle in the Ho Chi Minh City for studying air pollution. The analytical data of standard reference material, toxic elements and natural radionuclides in seawater are also presented. (author)

  3. Progress report on neutron activation analysis at Dalat Nuclear Research Reactor

    International Nuclear Information System (INIS)

    Tuan, Nguyen Ngoc

    2003-01-01

    Neutron Activation Analysis (NAA) is one of most powerful techniques for the simultaneous multi-elements analysis. This technique has been studied and applied to analyze major, minor and trace elements in Geological, Biological and Environmental samples at Dalat Nuclear Research Reactor. At the sixth Workshop, February 8-11, 1999, Yojakarta, Indonesia we had a report on Current Status of Neutron Activation Analysis using Dalat Nuclear Research Reactor. Another report on Neutron Activation Analysis at the Dalat Nuclear Research Reactor also was presented at the seventh Workshop in Taejon, Korea from November 20-24, 2000. So in this report, we would like to present the results obtained of the application of NAA at NRI for one year as follows: (1) Determination of the concentrations of noble, rare earth, uranium, thorium and other elements in Geological samples according to requirement of clients particularly the geologists, who want to find out the mineral resources. (2) The analysis of concentration of radionuclides and nutrient elements in foodstuffs to attend the program on Asian Reference Man. (3) The evaluation of the contents of trace elements in crude oil and basement rock samples to determine original source of the oil. (4) Determination of the elemental composition of airborne particle in the Ho Chi Minh City for studying air pollution. The analytical data of standard reference material, toxic elements and natural radionuclides in seawater are also presented. (author)

  4. Current face of acute otitis media: microbiology and prevalence resulting from widespread use of heptavalent pneumococcal conjugate vaccine.

    Science.gov (United States)

    Brunton, Stephen

    2006-01-01

    Many causes can be proposed for a change in the microbiologic makeup of a specific disease state. However, when viewed through the scope of recent events, only one is likely to be the true cause of a change in the microbiology of acute otitis media (AOM): the release and widespread use of heptavalent pneumococcal conjugate vaccine (PCV-7). The aim of this report was to review the microbiology and prevalence of AOM before and after the release and widespread use of PCV-7. For this brief review, we used a MEDLINE search to identify English-language literature related to the microbiology of AOM before and after the release of PCV-7 in 2000 in the United States (key terms: acute otitis media, AOM, Haemophilus influenzae, H influenzae, Streptococcus pneumoniae, and S pneumoniae; years: 1980-2005). Studies using tympanocentesis to identify the pathogen in recurrent or persistent AOM were examined; US studies reporting AOM microbiology before and after the release of PCV-7 in the same population were considered for the post-PCV-7 analysis. Following the release of PCV-7, a decrease in the overall rates of AOM was noted. This decrease brings into question the resultant effect on the microbiology of AOM. Our literature search revealed 2 studies that examined the microbiology of AOM before and after the release of PCV-7 in the United States. These 2 studies, conducted in dispersed geographic regions (rural Kentucky and Rochester, New York), illustrated a change in the predominant causative pathogen in AOM, from S pneumoniae to H influenzae in the population of children 7 to 24 months of age with recurrent AOM. Given the time period of the change, these shifts could be related to the release and widespread use of PCV-7. Since the 1990s, the predominant causative pathogen in recurrent AOM changed from S pneumoniae to H influenzae, possibly as a result of the release and widespread use of PCV 7. Although PCV-7 use was slowed from August 2001 to May 2003 and again from February

  5. Widespread IgE-mediated hypersensitivity in the Sudan to the 'green nimitti' midge, Cladotanytarsus lewisi (Diptera: Chironomidae) II. Identification of a major allergen.

    Science.gov (United States)

    Gad El Rab, M O; Thatcher, D R; Kay, A B

    1980-01-01

    A major allergen has been identified in an aqueous extract of the 'green nimitti' midge, Cladotanytarsus lewisi (Diptera: Chironomidae). Following chromatography on Sephadex G-100 allergenic activity, as assessed by skin ('prick') testing, eluted as two closely related peaks (pools I and II) at about 50% bed volume. When these pools were applied separately to columns of CM-cellulose, activity in each eluted with 0 . 05 M NaCl. Isoelectric focusing of the unfractionated allergen gave a single peak of activity at pI 4 . 3. By SDS--PAGE, biological activity in the whole 'green nimitti' extract and the material eluting from both pools I and II of the Sephadex G-100 column migrated to the same positions and were associated with a molecular size of 15,000--20,000 daltons. Skin test reactivity of the unfractionated material and the Sephadex G-100 pool I and II eluates were all destroyed following incubation with trypsin, chymotrypsin, thermolysin and neuraminidase. These experiments indicate that a major allergen derived from the 'green nimitti' midge, a cause of widespread and severe immediate-type allergy in the Sudan, is an acidic glycoprotein of 15,000--20,000 molecular weight. Images Fig. 3 PMID:7438559

  6. Atmospheric Research and Public Outreach Activities at Grandfather Mountain, North Carolina

    Science.gov (United States)

    Perry, B.; Pope, J.; Kelly, G.; Sherman, J. P.; Taubman, B.

    2012-12-01

    Promoting scientific and public understanding of mountain meteorological processes, particularly in the context of climate variability and change, remains a formidable challenge. Mountain environments present considerable difficulties in the collection of surface and atmospheric observations due to complex topography and resulting high spatial and temporal variability of the atmospheric processes. A collaborative partnership between Appalachian State University (ASU) and the Grandfather Mountain Stewardship Foundation (GMSF) in the southern Appalachian Mountains of North Carolina has provided an outstanding opportunity to integrate atmospheric research and outreach activities. The NASA-funded Climate Action Network through Direct Observations and Outreach (CAN-DOO) project directly supports the research and education activities and places them in the context of climate variability and change. This paper introduces the manual observations and citizen science activities, automated meteorological measurements, and public outreach initiatives on Grandfather Mountain and presents preliminary findings. In support of project objectives, GMSF staff makes daily measurements of precipitation, snow water equivalent, snow depth, and aerosol optical depth, while also encouraging citizen scientists to participate in the daily meteorological measurements. Team members have developed real-time displays of meteorological conditions for the two main visitor's centers and website, and have also created interactive climate science public displays. ASU scientists and GMSF staff have worked together to install and operate two research-quality meteorological stations at 1609 m asl that measure temperature, relative humidity, wind speed and direction, pressure, precipitation, and present weather. Preliminary results of research activities suggest that extreme wind gusts >50 m s -1 and severe icing due to riming and freezing rain are a frequent occurrence on Grandfather Mountain

  7. The Publication of Research Data: Researcher Attitudes and Behaviour

    Directory of Open Access Journals (Sweden)

    Aaron Griffiths

    2009-06-01

    Full Text Available Normal 0 There is now widespread recognition that data are a valuable long-term resource and that making them publicly available is a way to realise their potential value - both as part of the scholarly record or for re-use by others. The Research Information Network (RIN report, To share or not to share: Publication and quality assurance of research data outputs (June 2008, investigates whether or not researchers make their research data available to others and the issues they encounter when doing so. Importantly, it seeks to do this by seeking the perspectives of researchers themselves. This paper reflects on how this relates to the more top-down literature on the subject. The discussion of the significance of the RIN's main findings is correlated to the four themes of the RIN report. Firstly, it discusses some distinctions in the types of data that should be shared and preserved and what needs to done to do so effectively. Secondly, it reflects on the motivations for and constraints on researchers publishing their data, and how funders and publishers can address them. Thirdly, it reviews some issues around how data are discovered, accessed and re-used. Finally, it discusses the scholarly and technical quality of published data.

  8. Research activity and capacity in primary healthcare: the REACH study: a survey.

    LENUS (Irish Health Repository)

    Glynn, Liam G

    2009-01-01

    BACKGROUND: Despite increased investment in primary care research and development (R&D), the level of engagement of primary healthcare professionals with research remains poor. The aim of this study is to assess the level of research activity and capacity for research among primary healthcare professionals in a health authority of over one million people in a mixed urban\\/rural setting in the West of Ireland. METHODS: A questionnaire, incorporating the R+D Culture Index, was sent to primary healthcare professionals in the HSE Western Region. Baseline characteristics were analysed with the use of one-way ANOVA and Chi-square test and the dependence of R&D Culture Index score on all sixteen available covariates was examined using multiple regression and regression tree modelling. RESULTS: There was a 54% response rate to the questionnaire. Primary healthcare professionals appeared to have an interest in and awareness of the importance of research in primary care but just 15% were found to be research active in this study. A more positive attitude towards an R&D culture was associated with having had previous research training, being currently involved in research and with not being a general practitioner (GP) (p < 0.001), but much variability in the R&D culture index score remained unexplained. CONCLUSION: Despite awareness of the importance of R&D in primary care and investment therein, primary healthcare professionals remain largely unengaged with the R&D process. This study highlights the issues that need to be addressed in order to encourage a shift towards a culture of R&D in primary care: lack of research training particularly in basic research skills and increased opportunities for research involvement. The use of the R&D Culture Index may enable groups to be identified that may be more research interested and can therefore be targeted in any future R&D strategy.

  9. Thematic network on the analysis of thorium and its isotopes in workplace materials. Interim report on current research activity and future research needs

    International Nuclear Information System (INIS)

    Howe, A.; Rosen, P.; White, M.

    1999-12-01

    The task of Work Package 1 (WP 1) of the EC Thematic Network 'The analysis of thorium and its isotopes in workplace materials' was to prepare an 'Inventory of current research activities in participating member states concerning thorium analysis in the workplace and environment'. The specific objective of WP 1 was 'to identify common research areas and co-ordinate activity for better management of resources'. This was to be achieved by carrying out a survey of network and national laboratories to establish the extent of current and proposed research activity in the field, evaluation of survey by network members, and production of a report containing results and conclusions. A preliminary literature review revealed that the majority of thorium analysis is carried out by Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or a radiochemical technique, alpha counting and neutron activation being the most popular. In many instances there is a preconcentration or separation step, which usually involves an ion exchange column to isolate the thorium and remove the majority of the matrix. Papers concerned with the application of ICP-MS were found to feature prominently amongst recent publications, which is not surprising, as the technique is fairly newly established. Thorium was most commonly measured in geological matrixes, including soil and ores. On the basis of the results of the literature review and survey of research activity, the Network identified two key areas of priority for further research: sample preparation methods for thorium analysis; and traceable standards and certified reference materials for thorium analysis. The Network considered how best to distribute the results to interested parties to facilitate links between laboratories with common research areas, and decided that: at this stage, the findings should simply be published in the form of this interim report, which is freely available to all interested parties; the Network should continue to

  10. Computer Based Procedures for Field Workers - FY16 Research Activities

    International Nuclear Information System (INIS)

    Oxstrand, Johanna; Bly, Aaron

    2016-01-01

    The Computer-Based Procedure (CBP) research effort is a part of the Light-Water Reactor Sustainability (LWRS) Program, which provides the technical foundations for licensing and managing the long-term, safe, and economical operation of current nuclear power plants. One of the primary missions of the LWRS program is to help the U.S. nuclear industry adopt new technologies and engineering solutions that facilitate the continued safe operation of the plants and extension of the current operating licenses. One area that could yield tremendous savings in increased efficiency and safety is in improving procedure use. A CBP provides the opportunity to incorporate context-driven job aids, such as drawings, photos, and just-in-time training. The presentation of information in CBPs can be much more flexible and tailored to the task, actual plant condition, and operation mode. The dynamic presentation of the procedure will guide the user down the path of relevant steps, thus minimizing time spent by the field worker to evaluate plant conditions and decisions related to the applicability of each step. This dynamic presentation of the procedure also minimizes the risk of conducting steps out of order and/or incorrectly assessed applicability of steps. This report provides a summary of the main research activities conducted in the Computer-Based Procedures for Field Workers effort since 2012. The main focus of the report is on the research activities conducted in fiscal year 2016. The activities discussed are the Nuclear Electronic Work Packages - Enterprise Requirements initiative, the development of a design guidance for CBPs (which compiles all insights gained through the years of CBP research), the facilitation of vendor studies at the Idaho National Laboratory (INL) Advanced Test Reactor (ATR), a pilot study for how to enhance the plant design modification work process, the collection of feedback from a field evaluation study at Plant Vogtle, and path forward to

  11. Computer Based Procedures for Field Workers - FY16 Research Activities

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bly, Aaron [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-09-01

    The Computer-Based Procedure (CBP) research effort is a part of the Light-Water Reactor Sustainability (LWRS) Program, which provides the technical foundations for licensing and managing the long-term, safe, and economical operation of current nuclear power plants. One of the primary missions of the LWRS program is to help the U.S. nuclear industry adopt new technologies and engineering solutions that facilitate the continued safe operation of the plants and extension of the current operating licenses. One area that could yield tremendous savings in increased efficiency and safety is in improving procedure use. A CBP provides the opportunity to incorporate context-driven job aids, such as drawings, photos, and just-in-time training. The presentation of information in CBPs can be much more flexible and tailored to the task, actual plant condition, and operation mode. The dynamic presentation of the procedure will guide the user down the path of relevant steps, thus minimizing time spent by the field worker to evaluate plant conditions and decisions related to the applicability of each step. This dynamic presentation of the procedure also minimizes the risk of conducting steps out of order and/or incorrectly assessed applicability of steps. This report provides a summary of the main research activities conducted in the Computer-Based Procedures for Field Workers effort since 2012. The main focus of the report is on the research activities conducted in fiscal year 2016. The activities discussed are the Nuclear Electronic Work Packages – Enterprise Requirements initiative, the development of a design guidance for CBPs (which compiles all insights gained through the years of CBP research), the facilitation of vendor studies at the Idaho National Laboratory (INL) Advanced Test Reactor (ATR), a pilot study for how to enhance the plant design modification work process, the collection of feedback from a field evaluation study at Plant Vogtle, and path forward to

  12. Quinoxaline 1, 4-di-N-oxides: Biological activities and mechanisms of actions

    Directory of Open Access Journals (Sweden)

    Guyue eCheng

    2016-03-01

    Full Text Available Quinoxaline 1, 4-di-N-oxides (QdNOs have manifold biological properties, including antimicrobial, antitumoral, antitrypanosomal and antiinflammatory/antioxidant activities. These diverse activities endow them broad applications and prospects in human and veterinary medicines. As QdNOs arouse widespread interest, the evaluation of their medicinal chemistry is still in progress. In the meantime, adverse effects have been reported in some of the QdNO derivatives. For example, genotoxicity and bacterial resistance have been found in QdNO antibacterial growth promoters, conferring urgent need for discovery of new QdNO drugs. However, the modes of actions of QdNOs are not fully understood, hindering the development and innovation of these promising compounds. Here, QdNOs are categorized based on the activities and usages, among which the antimicrobial activities are consist of antibacterial, antimycobacterial and anticandida activities, and the antiprotozoal activities include antitrypanosomal, antimalarial, antitrichomonas and antiamoebic activities. The structure-activity relationship and the mode of actions of each type of activity of QdNOs are summarized, and the toxicity and the underlying mechanisms are also discussed, providing insight for the future research and development of these fascinating compounds.

  13. Radiation applications research and facilities in AECL research company

    Science.gov (United States)

    Iverson, S. L.

    In the 60's and 70's Atomic Energy of Canada had a very active R&D program to discover and develop applications of ionizing radiation. Out of this grew the technology underlying the company's current product line of industrial irradiators. With the commercial success of that product line the company turned its R&D attention to other activities. Presently, widespread interest in the use of radiation for food processing and the possibility of developing reliable and competitive machine sources of radiation hold out the promise of a major increase in industrial use of radiation. While many of the applications being considered are straightforward applications of existing knowledge, others depend on more subtle effects including combined effects of two or more agents. Further research is required in these areas. In March 1985 a new branch, Radiation Applications Research, began operations with the objective of working closely with industry to develop and assist the introduction of new uses of ionizing radiation. The Branch is equipped with appropriate analytical equipment including HPLC (high performance liquid chromatograph) and GC/MS (gas chromatograph/mass spectrometer) as well as a Gammacell 220 and an I-10/1, one kilowatt 10 MeV electron accelerator. The accelerator is located in a specially designed facility equipped for experimental irradiation of test quantities of packaged products as well as solids, liquids and gases in various configurations. A conveyor system moves the packaged products from the receiving area, through a maze, past the electron beam at a controlled rate and finally to the shipping area. Other necessary capabilities, such as gamma and electron dosimetry and a microbiology laboratory, have also been developed. Initial projects in areas ranging from food through environmental and industrial applications have been assessed and the most promising have been selected for further work. As an example, the use of charcoal adsorbent beds to concentrate

  14. Graduate nuclear engineering programmes motivate educational and research activities

    International Nuclear Information System (INIS)

    Mavko, B.

    2000-01-01

    Some fifteen years ago the University of Ljubljana, Faculty for Mathematics and Physics together with the national research organisation the J. Stefan jointly established a Graduate programme of Nuclear Engineering. From the onset, the programme focused on nuclear technology, nuclear safety, and reactor physics and environment protection. Over the years this graduate programme has became the focal point of nuclear related, research and educational activities in Slovenia. It has grown into a meeting ground for recognised national and distinguished foreign educators and experienced professionals from the industry. In conjunction with an important national project, supported by the Slovenian government, entitled 'Jung Researcher' it also enhances the knowledge transfer to the next generation. Since the programme was introduced, the interest for this programme has been steadily growing. Accordingly, a number of PhD and MS degrees in NE have been awarded. The graduates of this programme have encountered very good job opportunities in nuclear as well as in non-nuclear sector. (author)

  15. High Energy Physics Division semiannual report of research activities, July 1, 1990--December 31, 1990

    International Nuclear Information System (INIS)

    Berger, E.; Moonier, P.; May, E.; Norem, J.

    1991-02-01

    A report is presented of research and development activities conducted in the High Energy Physics Division at Argonne National Laboratory during the six month period July 1 through December 31, 1990. Analyses of data from experiments performed by members of the Division are summarized, and the status of experiments taking data and of those being prepared is reviewed. Descriptions are included of research on theoretical and phenomenological topics in particle physics. Progress reports are provided on accelerator research and development, detector research and development, and experimental facilities research. Lists are presented of publications, of colloquia and conference talks, and of significant external community activities of members of the Division

  16. Physical activity of pregnant women in the light of scientific research - a review of the literature

    Directory of Open Access Journals (Sweden)

    Anna Sass

    2017-08-01

    Full Text Available Introduction: Physical activity during pregnancy is very important due to health benefits for women and fetus. Undoubtedly, physical activity should be adapted to the current psychophysical abilities of pregnant women. During that time, the physical effort should be taken by appropriate intensity, also the forms of physical activity should be general aimed in current pregnancy state. Undoubtedly the simplest form of physical activity for pregnant women is walk, as well as swimming, gymnastics, yoga and pilates. Exercises should have wide impact on her body and muscles. The aim of the study is to identify the physical activity of pregnant women in available scientific publications. Further goal is the assessment of the knowledge about the physical activity of pregnant women based on the current review of the literature. Research Methods: The following databases and scientific browsers were used and tracked for the purpose of the research objective: Pub Med, Retina Medical Search, Medline Plus, Europe PMC, POPLINE, Google Scholar. During searching for a results the keywords phrases were written in English: physical activity in pregnancy, pregnancy exercises, fitness, yoga, pilates, swimming and pelvic floor exercises during pregnancy. Conclusions: The current researches among the population of pregnant women are methodologically differentiated and not coherent in the subject. The implication of unexplored issues about pregnant women is the differentiation in directions of researches about the physical activity of pregnant women. It seems that is important to design and program an prospective research by using objective techniques to explore the pregnant women’s behavior, lifestyle and physical activity.

  17. Clinical research data sharing: what an open science world means for researchers involved in evidence synthesis.

    Science.gov (United States)

    Ross, Joseph S

    2016-09-20

    The International Committee of Medical Journal Editors (ICMJE) recently announced a bold step forward to require data generated by interventional clinical trials that are published in its member journals to be responsibly shared with external investigators. The movement toward a clinical research culture that supports data sharing has important implications for the design, conduct, and reporting of systematic reviews and meta-analyses. While data sharing is likely to enhance the science of evidence synthesis, facilitating the identification and inclusion of all relevant research, it will also pose key challenges, such as requiring broader search strategies and more thorough scrutiny of identified research. Furthermore, the adoption of data sharing initiatives by the clinical research community should challenge the community of researchers involved in evidence synthesis to follow suit, including the widespread adoption of systematic review registration, results reporting, and data sharing, to promote transparency and enhance the integrity of the research process.

  18. International Field Research with Undergraduate Students: Investigating Active Tectonics of the Nicoya Peninsula, Costa Rica

    Science.gov (United States)

    Marshall, J. S.; Gardner, T. W.; Protti, M.

    2005-12-01

    Over the past eight years, 18 undergraduate students from 12 U.S. and Costa Rican universities and colleges have participated in field research projects investigating coastal tectonics on the Nicoya Peninsula, Costa Rica. These projects have been organized around two different models: 1) a month-long "field camp" with 10 students and 5 project faculty (Keck Geology Consortium Project, 1998), and 2) several two-week field projects with 1-3 students and one faculty advisor (Cal Poly Pomona University and Trinity University). Under the direction of the authors, each of these projects has been carefully designed to provide a new piece to a larger research puzzle. The Nicoya Peninsula lies along Costa Rica's northern Pacific coast inboard of the Middle America Trench where the Cocos and Caribbean plates converge at 10 cm/yr. In 1950, the peninsula was shaken by a ~M 7.7 subduction earthquake that produced widespread damage and 0.5-1.0 m of coseismic coastal uplift. With a large slip deficit since 1950, the Nicoya Peninsula is viewed as a high-potential seismic gap. Field study of uplifted Quaternary marine terraces along the Nicoya coastline provides undergraduate students with a unique opportunity to examine rapid forearc deformation related to large subduction earthquakes. The field research conducted by each of these students provides the basis for a senior thesis at their home institution. In most cases, the students have focused their individual work on separate, but adjacent field areas. Collectively, each of these projects has generated significant data that contribute toward of an ongoing investigation of fore arc tectonics and subduction cycle earthquakes along the Costa Rican Pacific margin.

  19. Gravel sediment routing from widespread, low-intensity landscape disturbance, Current River basin, Missouri

    Science.gov (United States)

    Jacobson, Robert B.; Gran, K.B.

    1999-01-01

    During the last 160 years, land-use changes in the Ozarks have had the potential to cause widespread, low-intensity delivery of excess amounts of gravel-sized sediment to stream channels. Previous studies have indicated that this excess gravel bedload is moving in wave-like forms through Ozarks drainage basins. The longitudinal, areal distribution of gravel bars along 160 km of the Current River, Missouri, was evaluated to determine the relative effects of valley-scale controls, tributary basin characteristics, and lagged sediment transport in creating areas of gravel accumulations. The longitudinal distribution of gravel-bar area shows a broad scale wave-like form with increases in gravel-bar area weakly associated with tributary junctions. Secondary peaks of gravel area with 1·8–4·1 km spacing (disturbance reaches) are superimposed on the broad form. Variations in valley width explain some, but not all, of the short-spacing variation in gravel-bar area. Among variables describing tributary drainage basin morphometry, present-day land use and geologic characteristics, only drainage area and road density relate even weakly to gravel-bar areal inventories. A simple, channel network-based sediment routing model shows that many of the features of the observed longitudinal gravel distribution can be replicated by uniform transport of sediment from widespread disturbances through a channel network. These results indicate that lagged sediment transport may have a dominant effect on the synoptic spatial distribution of gravel in Ozarks streams; present-day land uses are only weakly associated with present-day gravel inventories; and valley-scale characteristics have secondary controls on gravel accumulations in disturbance reaches.

  20. Hot heads & cool bodies: The conundrums of human brown adipose tissue (BAT) activity research.

    Science.gov (United States)

    Bahler, Lonneke; Holleman, Frits; Booij, Jan; Hoekstra, Joost B; Verberne, Hein J

    2017-05-01

    Brown adipose tissue is able to increase energy expenditure by converting glucose and fatty acids into heat. Therefore, BAT is able to increase energy expenditure and could thereby facilitate weight loss or at least weight maintenance. Since cold is a strong activator of BAT, most prospective research is performed during cold to activate BAT. In current research, there are roughly two methods of cooling. Cooling by lowering ambient air temperature, which uses a fixed temperature for all subjects and personalized cooling, which uses cooling blankets or vests with temperatures that can be adjusted to the individual set point of shivering. These methods might trigger mechanistically different cold responses and hence result in a different BAT activation. This hypothesis is underlined by two studies with the same research question (difference in BAT activity between Caucasians and South Asians) one study found no differences in BAT activity whereas the other did found differences in BAT activity. Since most characteristics (e.g. age, BMI) were similar in the two studies, the best explanation for the differences in outcomes is the use of different cooling protocols. One of the reasons for differences in outcomes might be the sensory input from the facial skin, which might be important for the activation of BAT. In this review we will elaborate on the differences between the two cooling protocols used to activate BAT. Copyright © 2017 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

  1. The Moral Vacuum in Teacher Education Research and Practice

    Science.gov (United States)

    Sanger, Matthew; Osguthorpe, Richard

    2013-01-01

    This chapter examines the gap between the widespread acknowledgment that teaching is a moral endeavor, on the one hand, and the lack of explicit, systematic teacher education research and practice to support preparing teachers for the moral aspects of teaching. After providing an initial description of the aforementioned gap, the chapter surveys…

  2. A Critical Analysis of the Research on Student Homelessness

    Science.gov (United States)

    Miller, Peter M.

    2011-01-01

    Since the onset of the economic recession, rates of student homelessness have increased rapidly in urban, suburban, and rural school districts throughout the United States. Despite the widespread urgency of the issue, there is a lack of general coherence in the research about how diverse conditions of homelessness affect students and how schools…

  3. French National Alliance for Energy Research Coordination - Ancre, Activity Report 2015-2016

    International Nuclear Information System (INIS)

    Alazard-Toux, Nathalie; Allard, Francis; Becue, Thierry; Bernard, Herve; Bourgoin, Jean-Philippe; Brault, Pascal; Carre, Franck; Chabrelie, Marie-Francoise; Charrue, Herve; Colonna, Paul; Compere, Chantal; Criqui, Patrick; David, Sylvain; Devezeaux, Jean-Guy; Dollet, Alain; Duplan, Jean-Luc; Fabre, Francoise; Ferrant, Pierre; Flamant, Gilles; Forti, Laurent; Gentier, Sylvie; Gouy, Jean-Philippe; Hadj-Said, Nouredine; Lacour, Jean-Jacques; Latroche, Michel; Legrand, Jack; Lemoine, Fabrice; Le Net, Elisabeth; Le Thiez, Pierre; Lhomme-Maublanc, Julie; Lucchese, Paul; Malbranche, Philippe; Mermilliod, Nicole; Most, Jean-Michel; Rondot, Yolande; Tilagone, Richard; Touboul, Francoise; Uster, Guillaume; Vidal, Olivier

    2017-01-01

    Created on 17 July 2009, ANCRE (French National Alliance for Energy Research Coordination) brings together 19 research and innovation bodies and higher education institution consortia in the field of energy. Its missions, carried out in liaison with competitiveness clusters and funding agencies, are to: - reinforce synergies and partnerships between research bodies, universities and companies, - identify scientific and technical challenges hampering industrial development, - propose research and innovation programs and approaches to their implementation, - contribute to the development of national research strategy in the field of energy, as well as funding agency program development. Its 2 main societal challenges are: Clean, secure and efficient energy, and Sustainable mobility and urban systems. ANCRE mobilizes 200 scientists involved in 10 programmatic groups (1 - Energy from biomass, 2 - Fossil energy, geothermal energy, critical metals, 3 - Nuclear energy, 4 - Solar energy, 5 - Ocean, hydraulic and wind energy, 6 - Transport, 7 - Buildings, 8 - Industries and agriculture, 9 - Energy forecasting and economics, 10 - Energy networks and associated storage) and 2 cross-disciplinary groups (Strategy, Europe and international). This activity report presents the ANCRE's 2015-2016 Highlights, its future challenges, its contribution to public policy-making, its close cooperation with the French national research agency and active participation in European programs, its mobilizing, structuring and uniting communities, and its knowledge production and dissemination

  4. Objectives of research activities in Biology Branch, Chalk River Nuclear Laboratories, 1976

    International Nuclear Information System (INIS)

    1977-03-01

    The primary responsibility assigned to the Biology Branch within the framework of CRNL has been an active engagement in basic research related to the assessment of radiation hazards, particularly those to be expected after exposure to relatively low doses of radiation delivered at low dose-rates. The present group is characterized by a broad interest in the entire chain of events by which the initial radiation-induced changes in the living cell are translated into biological effects, with a special focus of attention on the mechanisms by which the initial damage can be largely repaired and by which the risks to man are modified under different circumstances. The basic concepts in radiation biology and risk estimates are reviewed in the light of recent literature on these topics. The current and proposed research activities of the Biology Branch are described. General and specific recommendations for future activities are given. (author)

  5. Interference Mitigation Technique Using Active Spaceborne Sensor Antenna in EESS (Active) and Space Research Service (Active) for Use in 500 MHz Bandwidth Near 9.6 GHz

    Science.gov (United States)

    Huneycutt, Bryan L.

    2005-01-01

    This document presents an interference mitigation technique using the active spaceborne sensor SAR3 antenna in the Earth Exploration-Satellite Service (active) and Space Research Service (active) for use in a 500 MHz bandwidth near 9.6 GHz. The purpose of the document is present antenna designs which offer lower sidelobes and faster rolloff in the sidelobes which in turn mitigates the interference to other services from the EESS (active) and SRS (active) sensors.

  6. Physical Activity, Sedentary Behavior, and Diet-Related eHealth and mHealth Research: Bibliometric Analysis.

    Science.gov (United States)

    Müller, Andre Matthias; Maher, Carol A; Vandelanotte, Corneel; Hingle, Melanie; Middelweerd, Anouk; Lopez, Michael L; DeSmet, Ann; Short, Camille E; Nathan, Nicole; Hutchesson, Melinda J; Poppe, Louise; Woods, Catherine B; Williams, Susan L; Wark, Petra A

    2018-04-18

    Electronic health (eHealth) and mobile health (mHealth) approaches to address low physical activity levels, sedentary behavior, and unhealthy diets have received significant research attention. However, attempts to systematically map the entirety of the research field are lacking. This gap can be filled with a bibliometric study, where publication-specific data such as citations, journals, authors, and keywords are used to provide a systematic overview of a specific field. Such analyses will help researchers better position their work. The objective of this review was to use bibliometric data to provide an overview of the eHealth and mHealth research field related to physical activity, sedentary behavior, and diet. The Web of Science (WoS) Core Collection was searched to retrieve all existing and highly cited (as defined by WoS) physical activity, sedentary behavior, and diet related eHealth and mHealth research papers published in English between January 1, 2000 and December 31, 2016. Retrieved titles were screened for eligibility, using the abstract and full-text where needed. We described publication trends over time, which included journals, authors, and countries of eligible papers, as well as their keywords and subject categories. Citations of eligible papers were compared with those expected based on published data. Additionally, we described highly-cited papers of the field (ie, top ranked 1%). The search identified 4805 hits, of which 1712 (including 42 highly-cited papers) were included in the analyses. Publication output increased on an average of 26% per year since 2000, with 49.00% (839/1712) of papers being published between 2014 and 2016. Overall and throughout the years, eHealth and mHealth papers related to physical activity, sedentary behavior, and diet received more citations than expected compared with papers in the same WoS subject categories. The Journal of Medical Internet Research published most papers in the field (9.58%, 164/1712). Most

  7. City of Camden, New Jersey Program offering widespread energy recovery (power): Final report

    Energy Technology Data Exchange (ETDEWEB)

    Witkowski, Stanley [City of Camden, NJ (United States). Dept. of Development and Planning Bureau of Housing Services

    2013-12-31

    The Camden Residential POWER Program, Program Offering Widespread Energy Recovery, is a program designed to benefit Camden homeowners, stabilize neighborhoods and put local contractors to work. Camden POWER granted up to $18,600 to fund energy efficient home improvements and necessary life/safety rehabilitation repairs. The program was designed as a self-sustaining, neighborhood approach to bringing long-term energy and financial savings to the community. Valuable home upgrades were completed, including high-efficiency furnaces, hot water heaters, insulation, insulated roofs and blower door guided air-sealing. The goal of all improvements were to reduce energy consumption, lower utility bills, improve property values and promote neighborhood stabilization.

  8. Research results in the field of information support for innovation activities

    Directory of Open Access Journals (Sweden)

    Ondřej Žižlavský

    2011-01-01

    Full Text Available The paper deals with an actual issue focused on one of the world wide problem – effective development of an innovation process in the company. Just innovation is deemed as an essential part of company’s efficiency and its development with an impact on overall performance and competitiveness. The purpose of this paper is to present and discuss knowledge and findings of original primary research into South-Moravian companies within two projects of Internal Grant Agency Faculty of Business and Management Brno University of Technology, which were conducted in 2009 and 2010. For this analysis a questionnaire survey was used – the results of the primary research reflect innovative activities from the top managers’ point of view. The scientific aim of the paper is to gain knowledge and analyse the present status of innovative activities as it pertains to Czech and foreign professional literature and in the Czech business environment. Authors proved with help of questionnaire survey that many companies still neglect information support of their innovation activities although given the importance of innovation as an engine of growth. Moreover, as shown by the primary research, the majority of companies lack a sophisticated marketing information system, modelling and analysis of the future market, analyses of customers, their behaviour and unsaid needs, definition of price strategies, and analysis of new expansion areas. These findings are not affirmative for our business environment.

  9. Dysregulation of the autonomic nervous system and its association with the presence and intensity of chronic widespread pain

    NARCIS (Netherlands)

    Barakat, A.; Vogelzangs, N.; Licht, C.M.M.; Geenen, R.; Macfarlane, G.J.; de Geus, E.J.C.; Smit, J.H.; Penninx, B.W.J.H.; Dekker, J.

    2012-01-01

    Objective To test the hypotheses that dysregulation of the autonomic nervous system (ANS) is associated with the presence of chronic widespread pain (CWP), and that dysregulation of the ANS is associated with higher pain intensity in CWP. Methods Cross-sectional data were obtained from 1,574

  10. Dysregulation of the Autonomic Nervous System and Its Association With the Presence and Intensity of Chronic Widespread Pain

    NARCIS (Netherlands)

    Barakat, Ansam; Vogelzangs, Nicole; Licht, Carmilla M. M.; Geenen, Rinie; Macfarlane, Gary J.; de Geus, Eco J. C.; Smit, Johannes H.; Penninx, Brenda W. J. H.; Dekker, Joost

    Objective. To test the hypotheses that dysregulation of the autonomic nervous system (ANS) is associated with the presence of chronic widespread pain (CWP), and that dysregulation of the ANS is associated with higher pain intensity in CWP. Methods. Cross-sectional data were obtained from 1,574

  11. Factors influencing observed and self-reported functional ability in women with chronic widespread pain: A cross-sectional study

    DEFF Research Database (Denmark)

    Amris, Kirstine; Wæhrens, Eva Ejlersen; Stockmarr, Anders

    2014-01-01

    -sectional with systematic data collection in a clinical setting. Subjects: A total of 257 consecutively enrolled women with chronic widespread pain. Methods: Multidimensional assessment using self-report and observation-based assessment tools identified to cover ICF categories included in the brief ICF Core Set for chronic...

  12. Therapeutic Ultrasound Research And Development From An Industrial And Commercial Perspective

    International Nuclear Information System (INIS)

    Seip, Ralf

    2009-01-01

    The objective of this paper is to share the challenges and opportunities as viewed from an industrial and commercial perspective that one encounters when performing therapeutic ultrasound research, development, manufacturing, and sales activities. Research in therapeutic ultrasound has become an active field in the last decade, spurred by technological advances in the areas of transducer materials, control electronics, treatment monitoring techniques, an ever increasing number of clinical applications, and private and governmental funding opportunities. The development of devices and methods utilizing therapeutic ultrasound to cure or manage disease is being pursued by startup companies and large established companies alike, driven by the promise of profiting at many levels from this new and disruptive technology. Widespread penetration within the clinical community remains elusive, with current approaches focusing on very specific applications and niche markets. Challenges include difficulties in securing capital to develop the technology and undertake costly clinical trials, a regulatory landscape that varies from country to country, resistance from established practitioners, and difficulties in assembling a team with the right mix of technological savvy and business expertise. Success is possible and increasing, however, as evidenced by several companies, initiatives, and products with measurable benefits to the patient, clinician, and companies alike.

  13. Therapeutic Ultrasound Research And Development From An Industrial And Commercial Perspective

    Science.gov (United States)

    Seip, Ralf

    2009-04-01

    The objective of this paper is to share the challenges and opportunities as viewed from an industrial and commercial perspective that one encounters when performing therapeutic ultrasound research, development, manufacturing, and sales activities. Research in therapeutic ultrasound has become an active field in the last decade, spurred by technological advances in the areas of transducer materials, control electronics, treatment monitoring techniques, an ever increasing number of clinical applications, and private and governmental funding opportunities. The development of devices and methods utilizing therapeutic ultrasound to cure or manage disease is being pursued by startup companies and large established companies alike, driven by the promise of profiting at many levels from this new and disruptive technology. Widespread penetration within the clinical community remains elusive, with current approaches focusing on very specific applications and niche markets. Challenges include difficulties in securing capital to develop the technology and undertake costly clinical trials, a regulatory landscape that varies from country to country, resistance from established practitioners, and difficulties in assembling a team with the right mix of technological savvy and business expertise. Success is possible and increasing, however, as evidenced by several companies, initiatives, and products with measurable benefits to the patient, clinician, and companies alike.

  14. Exploring the use of research evidence in health-enhancing physical activity policies

    DEFF Research Database (Denmark)

    Hämäläinen, Riitta-Maija; Aro, Arja R.; van de Goor, Ien

    2015-01-01

    informed by research evidence compared to others. The aims of the present article are to explore the use of research evidence in health-enhancing physical activity (HEPA) policies, identify when research evidence was used, and find what other types of evidence were employed in HEPA policymaking. Methods......Background The gaps observed between the use of research evidence and policy have been reported to be based on the different methods of using research evidence in policymaking by researchers and actual policymakers. Some policies and policymaking processes may therefore be particularly well...... Multidisciplinary teams from six EU member states analysed the use of research evidence and other kinds of evidence in 21 HEPA policies and interviewed 86 key policymakers involved in the policies. Qualitative content analysis was conducted on both policy documents and interview data. Results Research evidence...

  15. High Energy Physics Division semiannual report of research activities, January 1 - June 30, 1997

    International Nuclear Information System (INIS)

    Norem, J.; Rezmer, R.; Wagner, R.

    1997-12-01

    This report is divided into: the experimental research program; theoretical physics program; accelerator research and development; and divisional computing activities. The experimental research program covers: experiments with data; experiments in planning or construction; and detector development. Work done for this period is summarized for each area

  16. The era of the wandering mind? Twenty-first century research on self-generated mental activity

    Directory of Open Access Journals (Sweden)

    Felicity eCallard

    2013-12-01

    Full Text Available The first decade of the twenty-first century was characterized by renewed scientific interest in self-generated mental activity (activity largely generated by the individual, rather than in response to experimenters’ instructions or specific external sensory inputs. To understand this renewal of interest, we interrogated the peer-reviewed literature from 2003–2012 (i to explore recent changes in use of terms for self-generated mental activity; (ii to investigate changes in the topics on which mind wandering research, specifically, focuses; and (iii to visualize co-citation communities amongst researchers working on self-generated mental activity. Our analyses demonstrated that there has been a dramatic increase in the term mind wandering, and a significant crossing-over of psychological investigations of mind wandering, specifically, into cognitive neuroscience. If this is, indeed, the ‘era of the wandering mind’, our paper calls for more explicit reflection to be given by mind wandering researchers to the terms they use, the topics and brain regions they focused on, and the research literatures that they implicitly foreground or ignore as not relevant.

  17. IAEA activities related to research reactor fuel conversion and spent fuel return programs

    International Nuclear Information System (INIS)

    Goldman, Ira N.; Adelfang, Pablo; Ritchie, Iain G.

    2005-01-01

    The IAEA has been involved for more than twenty years in supporting international nuclear non-proliferation efforts associated with reducing the amount of highly enriched uranium (HEU) in international commerce. IAEA projects and activities have directly supported the Reduced Enrichment for Research and Test Reactors (RERTR) programme, as well as directly associated efforts to return research reactor fuel to the country where it was originally enriched. IAEA efforts have included the development and maintenance of several data bases with information related to research reactors and research reactor spent fuel inventories that have been essential in planning and managing both RERTR and spent fuel return programmes. Other IAEA regular budget programs have supported research reactor fuel conversion from HEU to low enriched uranium (LEU), and in addressing issues common to many member states with spent fuel management problems and concerns. The paper briefly describes IAEA involvement since the early 1980's in these areas, including regular budget and Technical Co-operation programme activities, and focuses on efforts in the past five years to continue to support and accelerate U.S. and Russian research reactor spent fuel return programmes. (author)

  18. Tobacco Control: Visualisation of Research Activity Using Density-Equalizing Mapping and Scientometric Benchmarking Procedures

    Directory of Open Access Journals (Sweden)

    Beatrix Groneberg-Kloft

    2009-06-01

    Full Text Available Background: Tobacco smoking continues to be a major preventable cause of death and disease and therefore tobacco control research is extremely important. However, research in this area is often hampered by a lack in funding and there is a need for scientometric techniques to display research efforts. Methods: The present study combines classical bibliometric tools with novel scientometric and visualizing techniques in order to analyse and categorise research in the field of tobacco control. Results: All studies related to tobacco control and listed in the ISI database since 1900 were identified by the use of defined search terms.Using bibliometric approaches, a continuous increase in qualitative markers such as collaboration numbers or citations were found for tobacco control research. The combination with density equalizing mapping revealed a distinct global pattern of research productivity and citation activity. Radar chart techniques were used to visualize bi- and multilateral research cooperation and institutional cooperation. Conclusions: The present study supplies a first scientometricapproach that visualises research activity in the field of tobacco control. It provides data that can be used for funding policy and the identification of research clusters.

  19. Cell-based therapeutics from an economic perspective: primed for a commercial success or a research sinkhole?

    Science.gov (United States)

    McAllister, Todd N; Dusserre, Nathalie; Maruszewski, Marcin; L'heureux, Nicolas

    2008-11-01

    Despite widespread hype and significant investment through the late 1980s and 1990s, cell-based therapeutics have largely failed from both a clinical and financial perspective. While the early pioneers were able to create clinically efficacious products, small margins coupled with small initial indications made it impossible to produce a reasonable return on the huge initial investments that had been made to support widespread research activities. Even as US FDA clearance opened up larger markets, investor interest waned, and the crown jewels of cell-based therapeutics went bankrupt or were rescued by corporate bailout. Despite the hard lessons learned from these pioneering companies, many of today's regenerative medicine companies are supporting nearly identical strategies. It remains to be seen whether or not our proposed tenets for investment and commercialization strategy yield an economic success or whether the original model can produce a return on investment sufficient to justify the large up-front investments. Irrespective of which approach yields a success, it is critically important that more of the second-generation products establish profitability if the field is to enjoy continued investment from both public and private sectors.

  20. Bacterial Leaf Scorch of Amenity Trees a Wide-Spread Problem of Economic Significance to the Urban Forest

    Science.gov (United States)

    James Lashomb; Alan Iskra; Ann Brooks Gould; George Hamilton

    2003-01-01

    Bacterial leaf scorch (BLS) of amenity trees is caused by the bacterium Xylella fastidiosa, a xylem-limited pathogen that causes water stress resulting in leaf scorch, decline, and eventual death of affected trees. Recent surveys indicate that BLS is widespread throughout the eastern half of the United States. In New Jersey, BLS primarily affects red and pin oaks...