WorldWideScience

Sample records for wave height hs

  1. A generalized multivariate regression model for modelling ocean wave heights

    Science.gov (United States)

    Wang, X. L.; Feng, Y.; Swail, V. R.

    2012-04-01

    In this study, a generalized multivariate linear regression model is developed to represent the relationship between 6-hourly ocean significant wave heights (Hs) and the corresponding 6-hourly mean sea level pressure (MSLP) fields. The model is calibrated using the ERA-Interim reanalysis of Hs and MSLP fields for 1981-2000, and is validated using the ERA-Interim reanalysis for 2001-2010 and ERA40 reanalysis of Hs and MSLP for 1958-2001. The performance of the fitted model is evaluated in terms of Pierce skill score, frequency bias index, and correlation skill score. Being not normally distributed, wave heights are subjected to a data adaptive Box-Cox transformation before being used in the model fitting. Also, since 6-hourly data are being modelled, lag-1 autocorrelation must be and is accounted for. The models with and without Box-Cox transformation, and with and without accounting for autocorrelation, are inter-compared in terms of their prediction skills. The fitted MSLP-Hs relationship is then used to reconstruct historical wave height climate from the 6-hourly MSLP fields taken from the Twentieth Century Reanalysis (20CR, Compo et al. 2011), and to project possible future wave height climates using CMIP5 model simulations of MSLP fields. The reconstructed and projected wave heights, both seasonal means and maxima, are subject to a trend analysis that allows for non-linear (polynomial) trends.

  2. Multiresolution wavelet-ANN model for significant wave height forecasting.

    Digital Repository Service at National Institute of Oceanography (India)

    Deka, P.C.; Mandal, S.; Prahlada, R.

    Hybrid wavelet artificial neural network (WLNN) has been applied in the present study to forecast significant wave heights (Hs). Here Discrete Wavelet Transformation is used to preprocess the time series data (Hs) prior to Artificial Neural Network...

  3. Small scale currents and ocean wave heights: from today's models to future satellite observations with CFOSAT and SKIM

    Science.gov (United States)

    Ardhuin, Fabrice; Gille, Sarah; Menemenlis, Dimitris; Rocha, Cesar; Rascle, Nicolas; Gula, Jonathan; Chapron, Bertrand

    2017-04-01

    Tidal currents and large oceanic currents, such as the Agulhas, Gulf Stream and Kuroshio, are known to modify ocean wave properties, causing extreme sea states that are a hazard to navigation. Recent advances in the understanding and modeling capability of ocean currents at scales of 10 km or less have revealed the ubiquitous presence of fronts and filaments. Based on realistic numerical models, we show that these structures can be the main source of variability in significant wave heights at scales less than 200 km, including important variations at 10 km. This current-induced variability creates gradients in wave heights that were previously overlooked and are relevant for extreme wave heights and remote sensing. The spectrum of significant wave heights is found to be of the order of 70⟨Hs ⟩2/(g2⟨Tm0,-1⟩2) times the current spectrum, where ⟨Hs ⟩ is the spatially-averaged significant wave height, ⟨Tm0,-1⟩ is the average energy period, and g is the gravity acceleration. This small scale variability is consistent with Jason-3 and SARAL along-track variability. We will discuss how future satellite mission with wave spectrometers can help observe these wave-current interactions. CFOSAT is due for launch in 2018, and SKIM is a proposal for ESA Earth Explorer 9.

  4. Extreme Value Predictions using Monte Carlo Simulations with Artificially Increased Wave Height

    DEFF Research Database (Denmark)

    Jensen, Jørgen Juncher

    2010-01-01

    It is well known from linear analyses in a stochastic seaway that the mean out-crossing rate ν(r) of a level r is given by ν(0)exp(-0.5ß2)where the reliability index ß=r/Sr. Here Sr is the standard deviation of the response and, hence, linearly dependent on the sig-nificant wave height Hs. For non...

  5. Encounter Probability of Individual Wave Height

    DEFF Research Database (Denmark)

    Liu, Z.; Burcharth, H. F.

    1998-01-01

    wave height corresponding to a certain exceedence probability within a structure lifetime (encounter probability), based on the statistical analysis of long-term extreme significant wave height. Then the design individual wave height is calculated as the expected maximum individual wave height...... associated with the design significant wave height, with the assumption that the individual wave heights follow the Rayleigh distribution. However, the exceedence probability of such a design individual wave height within the structure lifetime is unknown. The paper presents a method for the determination...... of the design individual wave height corresponding to an exceedence probability within the structure lifetime, given the long-term extreme significant wave height. The method can also be applied for estimation of the number of relatively large waves for fatigue analysis of constructions....

  6. Encounter Probability of Significant Wave Height

    DEFF Research Database (Denmark)

    Liu, Z.; Burcharth, H. F.

    The determination of the design wave height (often given as the significant wave height) is usually based on statistical analysis of long-term extreme wave height measurement or hindcast. The result of such extreme wave height analysis is often given as the design wave height corresponding to a c...

  7. On the Extreme Wave Height Analysis

    DEFF Research Database (Denmark)

    Burcharth, H. F.; Liu, Zhou

    1994-01-01

    The determination of the design wave height is usually based on the statistical analysis of long-term extreme wave height measurements. After an introduction to the procedure of the extreme wave height analysis, the paper presents new development concerning various aspects of the extreme wave...... height analysis. Finally, the paper gives a practical example based on a data set of the hindcasted wave heights for a deep water location in the Mediterranean Sea....

  8. Challenges in Defining Tsunami Wave Height

    Science.gov (United States)

    Stroker, K. J.; Dunbar, P. K.; Mungov, G.; Sweeney, A.; Arcos, N. P.

    2017-12-01

    The NOAA National Centers for Environmental Information (NCEI) and co-located World Data Service for Geophysics maintain the global tsunami archive consisting of the historical tsunami database, imagery, and raw and processed water level data. The historical tsunami database incorporates, where available, maximum wave heights for each coastal tide gauge and deep-ocean buoy that recorded a tsunami signal. These data are important because they are used for tsunami hazard assessment, model calibration, validation, and forecast and warning. There have been ongoing discussions in the tsunami community about the correct way to measure and report these wave heights. It is important to understand how these measurements might vary depending on how the data were processed and the definition of maximum wave height. On September 16, 2015, an 8.3 Mw earthquake located 48 km west of Illapel, Chile generated a tsunami that was observed all over the Pacific region. We processed the time-series water level data for 57 tide gauges that recorded this tsunami and compared the maximum wave heights determined from different definitions. We also compared the maximum wave heights from the NCEI-processed data with the heights reported by the NOAA Tsunami Warning Centers. We found that in the near field different methods of determining the maximum tsunami wave heights could result in large differences due to possible instrumental clipping. We also found that the maximum peak is usually larger than the maximum amplitude (½ peak-to-trough), but the differences for the majority of the stations were Warning Centers. Since there is currently only one field in the NCEI historical tsunami database to store the maximum tsunami wave height, NCEI will consider adding an additional field for the maximum peak measurement.

  9. Real time wave measurements and wave hindcasting in deep waters

    Digital Repository Service at National Institute of Oceanography (India)

    Anand, N.M.; Mandal, S.; SanilKumar, V.; Nayak, B.U.

    Deep water waves off Karwar (lat. 14~'45.1'N, long. 73~'34.8'E) at 75 m water depth pertaining to peak monsoon period have been measured using a Datawell waverider buoy. Measured wave data show that the significant wave height (Hs) predominantly...

  10. Extreme Wave Analysis by Integrating Model and Wave Buoy Data

    Directory of Open Access Journals (Sweden)

    Fabio Dentale

    2018-03-01

    Full Text Available Estimating the extreme values of significant wave height (HS, generally described by the HS return period TR function HS(TR and by its confidence intervals, is a necessity in many branches of coastal science and engineering. The availability of indirect wave data generated by global and regional wind and wave model chains have brought radical changes to the estimation procedures of such probability distribution—weather and wave modeling systems are routinely run all over the world, and HS time series for each grid point are produced and published after assimilation (analysis of the ground truth. However, while the sources of such indirect data are numerous, and generally of good quality, many aspects of their procedures are hidden to the users, who cannot evaluate the reliability and the limits of the HS(TR deriving from such data. In order to provide a simple engineering tool to evaluate the probability of extreme sea-states as well as the quality of such estimates, we propose here a procedure based on integrating HS time series generated by model chains with those recorded by wave buoys in the same area.

  11. Empirical Guidelines for Use of Irregular Wave Model to Estimate Nearshore Wave Height.

    Science.gov (United States)

    1982-07-01

    height, the easier to use tech- nique presented by McClenan (1975) was employed. The McClenan technique uti- lizes a monogram which was constructed from...the SPM equations and gives the same results. The inputs to the monogram technique are the period, the deep- water wave height, the deepwater wave

  12. Ocean Wave Parameters Retrieval from Sentinel-1 SAR Imagery

    Directory of Open Access Journals (Sweden)

    Weizeng Shao

    2016-08-01

    Full Text Available In this paper, a semi-empirical algorithm for significant wave height (Hs and mean wave period (Tmw retrieval from C-band VV-polarization Sentinel-1 synthetic aperture radar (SAR imagery is presented. We develop a semi-empirical function for Hs retrieval, which describes the relation between Hs and cutoff wavelength, radar incidence angle, and wave propagation direction relative to radar look direction. Additionally, Tmw can be also calculated through Hs and cutoff wavelength by using another empirical function. We collected 106 C-band stripmap mode Sentinel-1 SAR images in VV-polarization and wave measurements from in situ buoys. There are a total of 150 matchup points. We used 93 matchups to tune the coefficients of the semi-empirical algorithm and the rest 57 matchups for validation. The comparison shows a 0.69 m root mean square error (RMSE of Hs with a 18.6% of scatter index (SI and 1.98 s RMSE of Tmw with a 24.8% of SI. Results indicate that the algorithm is suitable for wave parameters retrieval from Sentinel-1 SAR data.

  13. Significant Wave Height under Hurricane Irma derived from SAR Sentinel-1 Data

    Science.gov (United States)

    Lehner, S.; Pleskachevsky, A.; Soloviev, A.; Fujimura, A.

    2017-12-01

    The 2017 Atlantic hurricane season was with three major hurricanes a particular active one. The Category 4 hurricane Irma made landfall on the Florida Keys on September 10th 2017 and was imaged several times by ESAs Sentinel-1 satellites in C-band and the TerraSAR-X satellite in X-band. The high resolution TerraSAR-X imagery showed the footprint of individual tornadoes on the sea surface together with their turbulent wake imaged as a dark line due to increased turbulence. The water-cloud structures of the tornadoes are analyzed and their sea surface structure is compared to optical and IR cloud imagery. An estimate of the wind field using standard XMOD algorithms is provided, although saturating under the strong rain and high wind speed conditions. Imaging the hurricanes by space radar gives the opportunity to observe the sea surface and thus measure the wind field and the sea state under hurricane conditions through the clouds even in this severe weather, although rain features, which are usually not observed in SAR become visible due to damping effects. The Copernicus Sentinel-1 A and B satellites, which are operating in C-band provided several images of the sea surface under hurricane Irma, Jose and Maria. The data were acquired daily and converted into measurements of sea surface wind field u10 and significant wave height Hs over a swath width of 280km about 1000 km along the orbit. The wind field of the hurricanes as derived by CMOD is provided by NOAA operationally on their web server. In the hurricane cases though the wind speed saturates at 20 m/sec and is thus too low in the area of hurricane wind speed. The technique to derive significant wave height is new though and does not show any calibration issues. This technique provides for the first time measurements of the areal coverage and distribution of the ocean wave height as caused by a hurricane on SAR wide swath images. Wave heights up to 10 m were measured under the forward quadrant of the hurricane

  14. Climate change signal and uncertainty in CMIP5-based projections of global ocean surface wave heights

    Science.gov (United States)

    Wang, Xiaolan L.; Feng, Yang; Swail, Val R.

    2015-05-01

    This study uses the analysis of variance approaches to quantify the climate change signal and uncertainty in multimodel ensembles of statistical simulations of significant wave height (Hs), which are based on the CMIP5 historical, RCP4.5 and RCP8.5 forcing scenario simulations of sea level pressure. Here the signal of climate change refers to the temporal variations caused by the prescribed forcing. "Significant" means "significantly different from zero at 5% level." In a four-model ensemble of Hs simulations, the common signal—the signal that is simulated in all the four models—is found to strengthen over time. For the historical followed by RCP8.5 scenario, the common signal in annual mean Hs is found to be significant in 16.6% and 82.2% of the area by year 2005 and 2099, respectively. The global average of the variance proportion of the common signal increases from 0.75% in year 2005 to 12.0% by year 2099. The signal is strongest in the eastern tropical Pacific (ETP), featuring significant increases in both the annual mean and maximum of Hs in this region. The climate model uncertainty (i.e., intermodel variability) is significant nearly globally; its magnitude is comparable to or greater than that of the common signal in most areas, except in the ETP where the signal is much larger. In a 20-model ensemble of Hs simulations for the period 2006-2099, the model uncertainty is found to be significant globally; it is about 10 times as large as the variability between the RCP4.5 and RCP8.5 scenarios. The copyright line for this article was changed on 10 JUNE 2015 after original online publication.

  15. Measuring sea surface height with a GNSS-Wave Glider

    Science.gov (United States)

    Morales Maqueda, Miguel Angel; Penna, Nigel T.; Foden, Peter R.; Martin, Ian; Cipollini, Paolo; Williams, Simon D.; Pugh, Jeff P.

    2017-04-01

    A GNSS-Wave Glider is a novel technique to measure sea surface height autonomously using the Global Navigation Satellite System (GNSS). It consists of an unmanned surface vehicle manufactured by Liquid Robotics, a Wave Glider, and a geodetic-grade GNSS antenna-receiver system, with the antenna installed on a mast on the vehicle's deck. The Wave Glider uses the differential wave motion through the water column for propulsion, thus guaranteeing an, in principle, indefinite autonomy. Solar energy is collected to power all on-board instrumentation, including the GNSS system. The GNSS-Wave Glider was first tested in Loch Ness in 2013, demonstrating that the technology is capable of mapping geoid heights within the loch with an accuracy of a few centimetres. The trial in Loch Ness did not conclusively confirm the reliability of the technique because, during the tests, the state of the water surface was much more benign than would normally be expect in the open ocean. We now report on a first deployment of a GNSS-Wave Glider in the North Sea. The deployment took place in August 2016 and lasted thirteen days, during which the vehicle covered a distance of about 350 nautical miles in the north western North Sea off Great Britain. During the experiment, the GNSS-Wave Glider experienced sea states between 1 (0-0.1 m wave heights) and 5 (2.5-4 m wave heights). The GNSS-Wave Glider data, recorded at 5 Hz frequency, were analysed using a post-processed kinematic GPS-GLONASS precise point positioning (PPP) approach, which were quality controlled using double difference GPS kinematic processing with respect to onshore reference stations. Filtered with a 900 s moving-average window, the PPP heights reveal geoid patterns in the survey area that are very similar to the EGM2008 geoid model, thus demonstrating the potential use of a GNSS-Wave Glider for marine geoid determination. The residual of subtracting the modelled or measured marine geoid from the PPP signal combines information

  16. Small-scale open ocean currents have large effects on wind wave heights

    Science.gov (United States)

    Ardhuin, Fabrice; Gille, Sarah T.; Menemenlis, Dimitris; Rocha, Cesar B.; Rascle, Nicolas; Chapron, Bertrand; Gula, Jonathan; Molemaker, Jeroen

    2017-06-01

    Tidal currents and large-scale oceanic currents are known to modify ocean wave properties, causing extreme sea states that are a hazard to navigation. Recent advances in the understanding and modeling capability of open ocean currents have revealed the ubiquitous presence of eddies, fronts, and filaments at scales 10-100 km. Based on realistic numerical models, we show that these structures can be the main source of variability in significant wave heights at scales less than 200 km, including important variations down to 10 km. Model results are consistent with wave height variations along satellite altimeter tracks, resolved at scales larger than 50 km. The spectrum of significant wave heights is found to be of the order of 70>>2/>(g2>>2>) times the current spectrum, where >> is the spatially averaged significant wave height, >> is the energy-averaged period, and g is the gravity acceleration. This variability induced by currents has been largely overlooked in spite of its relevance for extreme wave heights and remote sensing.Plain Language SummaryWe show that the variations in currents at scales 10 to 100 km are the main source of variations in wave heights at the same scales. Our work uses a combination of realistic numerical models for currents and waves and data from the Jason-3 and SARAL/AltiKa satellites. This finding will be of interest for the investigation of extreme wave heights, remote sensing, and air-sea interactions. As an immediate application, the present results will help constrain the error budget of the up-coming satellite missions, in particular the Surface Water and Ocean Topography (SWOT) mission, and decide how the data will have to be processed to arrive at accurate sea level and wave measurements. It will also help in the analysis of wave measurements by the CFOSAT satellite.

  17. A Rational Procedure for Determination of Directional Individual Design Wave Heights

    DEFF Research Database (Denmark)

    Sterndorff, M.; Sørensen, John Dalsgaard

    2001-01-01

    For code-based LRFD and for reliability-based assessment of offshore structures such as steel platforms it is essential that consistent directional and omnidirectional probability distributions for the maximum significant wave height, the maximum individual wave height, and the maximum individual...

  18. Significant wave height retrieval from synthetic radar images

    NARCIS (Netherlands)

    Wijaya, Andreas Parama; van Groesen, Embrecht W.C.

    2014-01-01

    In many offshore activities radar imagery is used to observe and predict ocean waves. An important issue in analyzing the radar images is to resolve the significant wave height. Different from 3DFFT methods that use an estimate related to the square root of the signal-to-noise ratio of radar images,

  19. Earthquake Scenario-Based Tsunami Wave Heights in the Eastern Mediterranean and Connected Seas

    Science.gov (United States)

    Necmioglu, Ocal; Özel, Nurcan Meral

    2015-12-01

    We identified a set of tsunami scenario input parameters in a 0.5° × 0.5° uniformly gridded area in the Eastern Mediterranean, Aegean (both for shallow- and intermediate-depth earthquakes) and Black Seas (only shallow earthquakes) and calculated tsunami scenarios using the SWAN-Joint Research Centre (SWAN-JRC) code ( Mader 2004; Annunziato 2007) with 2-arcmin resolution bathymetry data for the range of 6.5—Mwmax with an Mw increment of 0.1 at each grid in order to realize a comprehensive analysis of tsunami wave heights from earthquakes originating in the region. We defined characteristic earthquake source parameters from a compiled set of sources such as existing moment tensor catalogues and various reference studies, together with the Mwmax assigned in the literature, where possible. Results from 2,415 scenarios show that in the Eastern Mediterranean and its connected seas (Aegean and Black Sea), shallow earthquakes with Mw ≥ 6.5 may result in coastal wave heights of 0.5 m, whereas the same wave height would be expected only from intermediate-depth earthquakes with Mw ≥ 7.0 . The distribution of maximum wave heights calculated indicate that tsunami wave heights up to 1 m could be expected in the northern Aegean, whereas in the Black Sea, Cyprus, Levantine coasts, northern Libya, eastern Sicily, southern Italy, and western Greece, up to 3-m wave height could be possible. Crete, the southern Aegean, and the area between northeast Libya and Alexandria (Egypt) is prone to maximum tsunami wave heights of >3 m. Considering that calculations are performed at a minimum bathymetry depth of 20 m, these wave heights may, according to Green's Law, be amplified by a factor of 2 at the coastline. The study can provide a basis for detailed tsunami hazard studies in the region.

  20. Wave Height Distribution Observed by Ships in the North Atlantic

    DEFF Research Database (Denmark)

    Olsen, Anders Smærup; Schrøter, Carsten; Jensen, Jørgen Juncher

    2005-01-01

    for the significant wave height, the relative speed and the ship heading relative to the wave direction is given. This distribution shows that for higher waves the crews avoid sailing in following sea and as expected the speed is decreased in higher waves. There is, however, still a relatively high probability...

  1. Azimuth cut-off model for significant wave height investigation along coastal water of Kuala Terengganu, Malaysia

    Science.gov (United States)

    Marghany, Maged; Ibrahim, Zelina; Van Genderen, Johan

    2002-11-01

    The present work is used to operationalize the azimuth cut-off concept in the study of significant wave height. Three ERS-1 images have been used along the coastal waters of Terengganu, Malaysia. The quasi-linear transform was applied to map the SAR wave spectra into real ocean wave spectra. The azimuth cut-off was then used to model the significant wave height. The results show that azimuth cut-off varied with the different period of the ERS-1 images. This is because of the fact that the azimuth cut-off is a function of wind speed and significant wave height. It is of interest to find that the significant wave height modeled from azimuth cut-off is in good relation with ground wave conditions. It can be concluded that ERS-1 can be used as a monitoring tool in detecting the significant wave height variation. The azimuth cut-off can be used to model the significant wave height. This means that the quasi-linear transform could be a good application to significant wave height variation during different seasons.

  2. Identification of wind fields for wave modeling near Qatar

    Science.gov (United States)

    Nayak, Sashikant; Balan Sobhana, Sandeepan; Panchang, Vijay

    2016-04-01

    Due to the development of coastal and offshore infrastructure in and around the Arabian Gulf, a large semi-enclosed sea, knowledge of met-ocean factors like prevailing wind systems, wind generated waves, and currents etc. are of great importance. Primarily it is important to identify the wind fields that are used as forcing functions for wave and circulation models for hindcasting and forecasting purposes. The present study investigates the effects of using two sources of wind-fields on the modeling of wind-waves in the Arabian Gulf, in particular near the coastal regions of Qatar. Two wind sources are considered here, those obtained from ECMWF and those generated by us using the WRF model. The wave model SWAN was first forced with the 6 hourly ERA Interim daily winds (from ECMWF) having spatial resolution of 0.125°. For the second option, wind fields were generated by us using the mesoscale wind model (WRF) with a high spatial resolution (0.1°) at every 30 minute intervals. The simulations were carried out for a period of two months (7th October-7th December, 2015) during which measurements were available from two moored buoys (deployed and operated by the Qatar Meteorological Department), one in the north of Qatar ("Qatar North", in water depth of 58.7 m) and other in the south ("Shiraouh Island", in water depth of 16.64 m). This period included a high-sea event on 11-12th of October, recorded by the two buoys where the significant wave heights (Hs) reached as high as 2.9 m (i.e. max wave height H ~ 5.22 m) and 1.9 (max wave height H ~ 3.4 m) respectively. Model results were compared with the data for this period. The scatter index (SI) of the Hs simulated using the WRF wind fields and the observed Hs was found to be about 30% and 32% for the two buoys (total period). The observed Hs were generally reproduced but there was consistent underestimation. (Maximum 27% for the high-sea event). For the Hs obtained with ERA interim wind fields, the underestimation was

  3. Investigation of Wave Height Reduction behind the Wave Dragon Wave Energy Converters and Application in Santander, Spain

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen Quvang Harck; Andersen, Thomas Lykke

    This paper deals with a case study on the wave height reduction behind floating Wave Dragon wave energy converters in Santander Bay, Spain. The study is performed using the MIKE21 Boussinesq model from DHI. The Wave Dragon transmission characteristics in the numerical wave propagation model...... are based on previously performed physical model tests in scale 1:51. Typical winter storm conditions are considered in the case study together with different stiffness in the mooring system of the floating device. From the study it is found that if multiple Wave Dragons are positioned in a farm the wave...

  4. Three-dimensional freak waves and higher-order wave-wave resonances

    Science.gov (United States)

    Badulin, S. I.; Ivonin, D. V.; Dulov, V. A.

    2012-04-01

    period October 14 - November 6, 2009 almost continuously. Antenna of 6 resistance wave gauges (a pentagon with one center gauge) is used to gain information on wave directions. Wave conditions vary from perfect still to storms with significant wave heights up to Hs = 1.7 meters and wind speeds 15m/s. Measurements with frequency 10Hz for dominant frequencies 0.1 - 0.2Hz fixed 40 freak wave events (criterium H/Hs > 2) and showed no dependence on Hs definitely. Data processing within frequency quasi-spectra approach and directional spectra reconstructions found pronounced features of essentially three-dimensional anomalous waves. All the events are associated with dramatic widening of instant frequency spectra in the range fp - f5w and stronger directional spreading. On the contrary, the classic Benjamin-Feir modulations show no definite links with the events and can be likely treated as dynamically neutral part of wave field. The apparent contradiction with the recent study (Saprykina, Dulov, Kuznetsov, Smolov, 2010) based on the same data collection can be explained partially by features of data processing. Physical roots of the inconsistency should be detailed in further studies. The work was supported by the Russian government contract 11.G34.31.0035 (signed 25 November 2010), Russian Foundation for Basic Research grant 11-05-01114-a, Ukrainian State Agency of Science, Innovations and Information under Contract M/412-2011 and ONR grant N000141010991. Authors gratefully acknowledge continuing support of these foundations.

  5. Automation of measurement of heights waves around a model ship; Mokeisen mawari no hako keisoku no jidoka

    Energy Technology Data Exchange (ETDEWEB)

    Ikehata, M; Kato, M; Yanagida, F [Yokohama National University, Yokohama (Japan). Faculty of Engineering

    1997-10-01

    Trial fabrication and tests were performed on an instrument to automate measurement of heights of waves around a model ship. The currently used electric wave height measuring instrument takes long time for measurement, hence poor in efficiency. The method for processing optical images also has a problem in accuracy. Therefore, a computer controlled system was structured by using AC servo motors in driving the X and Y axes of a traverse equipment. Equipment was fabricated to automate the wave height measurement, in which four servo type wave height meters are installed on a moving rack in the lateral (Y-axial) direction so that wave heights to be measured by four meters can be measured automatically all at once. Wave heights can be measured continuously by moving the moving rack at a constant speed, verifying that wave shapes in longitudinal cross sections can be acquired by only one towing. Time required in the measurements using the instrument was 40 hours as a net time for fixed point measurement and 12 hours for continuous measurement, or 52 hours in total. On the other hand, the time may reach 240 hours for fixed point measurement when the conventional all-point manual traverse equipment is used. Enormous effects were obtained from automating the instrument. Collection of wave height data will continue also on tankers and other types of ships. 2 refs., 8 figs., 1 tab.

  6. Final Report for Project: Impacts of stratification and non-equilibrium winds and waves on hub-height winds

    Energy Technology Data Exchange (ETDEWEB)

    Patton, Edward G. [Univ. Corporation for Atmospheric Research, Boulder, CO (United States)

    2015-07-14

    wind plant scale. Overall project conclusions include; In the presence of fast-moving swell (significant wave height Hs = 6.4 m, and phase speed cp = 18 ms-1), the atmospheric boundary layer grows more rapidly when waves propagate opposite to the winds compared to when winds and waves are aligned. Pressure drag increases by nearly a factor of 2 relative to the turbulent stress for the extreme case where waves propagate at 180° compared to the pressure gradient forcing. Net wind speed reduces by nearly 15% at hub-height for the 180°-case compared to the 0°-case, and turbulence intensities increase by nearly a factor of 2. These impacts diminish with decreasing wave age; Stratification increases hub height wind speeds and increases the vertical shear of the mean wind across the rotor plane. Fortuitously, this stability-induced enhanced shear does not influence turbulence intensity at hub height, but does increase (decrease) turbulence intensity below (above) hub height. Increased stability also increases the wave-induced pressure stress by ~ 10%; Off the East Coast of the United States during Coupled Boundary Layers Air-Sea Transfer - Low Wind (CBLAST-Low), cases with short fetch include thin stable boundary layers with depths of only a few tens of meters. In the coastal zone, the relationship between the mean wind and the surface fiction velocity (u*(V )) is significantly related to wind direction for weak winds but is not systematically related to the air sea difference of virtual potential temperature, δθv; since waves generally propagate from the south at the Air-Sea Interaction Tower (ASIT) tower, these results suggest that under weak wind conditions waves likely influence surface stress more than stratification does; and Winds and waves are frequently misaligned in the coastal zone. Stability conditions persist for long duration. Over a four year period, the Forschungsplattformen in Nord- und Ostsee Nr. 1 (FINO1) tower (a site with long fetch

  7. Seasonal distribution of wave heights off Yanam on the east coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Nayak, B.U.; Chandramohan, D.; Sakhardande, R.N.

    , maximum wave height and zero crossing wave period are presented and discussed. Inter-comparison of wave parameters computEd. by the three different methods was also done and linear relationships were obtainEd. by the method of least square...

  8. Modeling nonstationary extreme wave heights in present and future climates of Greek Seas

    Directory of Open Access Journals (Sweden)

    Panagiota Galiatsatou

    2016-01-01

    Full Text Available In this study the generalized extreme value (GEV distribution function was used to assess nonstationarity in annual maximum wave heights for selected locations in the Greek Seas, both in the present and future climates. The available significant wave height data were divided into groups corresponding to the present period (1951–2000, a first future period (2001–2050, and a second future period (2051–2100. For each time period, the parameters of the GEV distribution were specified as functions of time-varying covariates and estimated using the conditional density network (CDN. For each location and selected time period, a total number of 29 linear and nonlinear models were fitted to the wave data, for a given combination of covariates. The covariates used in the GEV-CDN models consisted of wind fields resulting from the Regional Climate Model version 3 (RegCM3 developed by the International Center for Theoretical Physics (ICTP with a spatial resolution of 10 km × 10 km, after being processed using principal component analysis (PCA. The results obtained from the best fitted models in the present and future periods for each location were compared, revealing different patterns of relationships between wind components and extreme wave height quantiles in different parts of the Greek Seas and different periods. The analysis demonstrates an increase of extreme wave heights in the first future period as compared with the present period, causing a significant threat to Greek coastal areas in the North Aegean Sea and the Ionian Sea.

  9. Inter-annual variations in wave characteristics off Ratnagiri, Northeast Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Johnson, G.; SanilKumar, V.; Singh, J.

    location off the central west coast of India during 2008 to 2010 is negligible. The studies based on satellite derived data and ERA-Interim data have indicated that the significant wave height is marginally increasing in the south Indian Ocean and Arabian... for the monsoon period is the same (~ 2 m) in different years. Similarly the variation in annual average Hs during 2010 to 2013 is negligible (< 0.1 m). The average Hs during the monsoon is around 3 times that in the non-monsoon period and ~ 2 times...

  10. Gridded 5-day mean sea surface height anomaly and significant wave height from Jason-1 and OSTM/Jason-2 satellites (NODC Accession 0065055)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains the gridded 5-day mean sea surface height anomaly (SSHA) and Ku Band significant wave height (SWH-KU) observed from Jason-1 and OSTM/Jason-2...

  11. Seasonal and Non-Seasonal Generalized Pareto Distribution to Estimate Extreme Significant Wave Height in The Banda Sea

    Science.gov (United States)

    Nursamsiah; Nugroho Sugianto, Denny; Suprijanto, Jusup; Munasik; Yulianto, Bambang

    2018-02-01

    The information of extreme wave height return level was required for maritime planning and management. The recommendation methods in analyzing extreme wave were better distributed by Generalized Pareto Distribution (GPD). Seasonal variation was often considered in the extreme wave model. This research aims to identify the best model of GPD by considering a seasonal variation of the extreme wave. By using percentile 95 % as the threshold of extreme significant wave height, the seasonal GPD and non-seasonal GPD fitted. The Kolmogorov-Smirnov test was applied to identify the goodness of fit of the GPD model. The return value from seasonal and non-seasonal GPD was compared with the definition of return value as criteria. The Kolmogorov-Smirnov test result shows that GPD fits data very well both seasonal and non-seasonal model. The seasonal return value gives better information about the wave height characteristics.

  12. On microseisms recorded near the Ligurian coast (Italy) and their relationship with sea wave height

    DEFF Research Database (Denmark)

    Ferretti, G.; Zunino, Andrea; Scafidi, D.

    2013-01-01

    data set including also observations from January to December 2011 is used to calibrate an empirical predictive relation for sea wave height whose functional form is a modified version of the classical definition of H13 . By means of a Markov chainMonte Carlo algorithm we set up a procedure...... to investigate the inverse problem and to find a set of parameter values for predicting sea wave heights from microseism....

  13. Distributions of freak wave heights measured in the North Sea

    International Nuclear Information System (INIS)

    Stansell, P.

    2004-01-01

    We present a statistical analysis of some of the largest waves occurring during 793 h of surface elevation measurements collected during 14 severe storms in the North Sea. This data contains 104 freak waves. It is found that the probability of occurrence of freak waves is only weekly dependent on the significant wave height, significant wave steepness and spectral bandwidth. The probability does show a slightly stronger dependency on the skew and kurtosis of the surface elevation data, but on removing the contribution to these measures from the presence of the freakwaves themselves, this dependency largely disappears. Distributions of extreme waves are modelled by fitting Generalised Pareto distributions, and extreme value distributions and return periods are given for freak waves in terms of the empirical fitted parameters. It is shown by comparison with these fits that both the Rayleigh distribution and the fit of Nerzic and Prevosto severely under-predict the probability of occurrence of extreme waves. For the most extreme freak wave in our data, the Rayleigh distribution over-predicts the return period by about 300 times when compared to the fitted model. (author)

  14. An operational wave forecasting system for the east coast of India

    Science.gov (United States)

    Sandhya, K. G.; Murty, P. L. N.; Deshmukh, Aditya N.; Balakrishnan Nair, T. M.; Shenoi, S. S. C.

    2018-03-01

    Demand for operational ocean state forecasting is increasing, owing to the ever-increasing marine activities in the context of blue economy. In the present study, an operational wave forecasting system for the east coast of India is proposed using unstructured Simulating WAves Nearshore model (UNSWAN). This modelling system uses very high resolution mesh near the Indian east coast and coarse resolution offshore, and thus avoids the necessity of nesting with a global wave model. The model is forced with European Centre for Medium-Range Weather Forecasts (ECMWF) winds and simulates wave parameters and wave spectra for the next 3 days. The spatial pictures of satellite data overlaid on simulated wave height show that the model is capable of simulating the significant wave heights and their gradients realistically. Spectral validation has been done using the available data to prove the reliability of the model. To further evaluate the model performance, the wave forecast for the entire year 2014 is evaluated against buoy measurements over the region at 4 waverider buoy locations. Seasonal analysis of significant wave height (Hs) at the four locations showed that the correlation between the modelled and observed was the highest (in the range 0.78-0.96) during the post-monsoon season. The variability of Hs was also the highest during this season at all locations. The error statistics showed clear seasonal and geographical location dependence. The root mean square error at Visakhapatnam was the same (0.25) for all seasons, but it was the smallest for pre-monsoon season (0.12 m and 0.17 m) for Puducherry and Gopalpur. The wind sea component showed higher variability compared to the corresponding swell component in all locations and for all seasons. The variability was picked by the model to a reasonable level in most of the cases. The results of statistical analysis show that the modelling system is suitable for use in the operational scenario.

  15. Estimation of sea surface wave height from Bhaskara II SAMIR data

    Digital Repository Service at National Institute of Oceanography (India)

    Rao, M.V.; Viswambharan, N.K.; Rao, L.V.G.

    from R V Gaveshani and visual observations from other ships as reported in IDWR) are available. Using this, an attempt has been made to obtain an empirical relation between brightness temperature and significant wave height. Linear correlation between...

  16. Variations mechanism in entropy of wave height field and its relation with thermodynamic entropy

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    This paper gives a brief description of annual period and seasonal variation in the wave height field entropy in the northeastern Pacific. A calculation of the quantity of the, received by lithosphere systems in the northern hemisphere is introduced. The wave heat field entropy is compared with the difference in the quantity of the sun's radiation heat. Analysis on the transfer method, period and lag of this seasonal variation led to the conclusion that the annual period and seasonal variation in the entropy of the wave height field in the Northwestern Pacific is due to the seasonal variation of the sun's radiation heat. Furthermore, the inconsistency between thermodynamic entropy and information entropy was studied.

  17. Encountered Wave Height Distributions for Ships in the North Atlantic

    DEFF Research Database (Denmark)

    Olsen, Anders Smærup; Schrøter, C.; Jensen, Jørgen Juncher

    2004-01-01

    About 20 000 observations of wave heights taken on board vessels sailing in the North Atlantic are presented. The data covers year 2002 and 2003 and stem from a variety of ship types. From the preliminary analysis of the data some conclusions are reached about the effect of weather routing whether...

  18. HS-RAID2: Optimizing Small Write Performance in HS-RAID

    Directory of Open Access Journals (Sweden)

    Yongfeng Dong

    2016-01-01

    Full Text Available HS-RAID (Hybrid Semi-RAID, a power-aware RAID, saves energy by grouping disks in the array. All of the write operations in HS-RAID are small write which degrade the storage system’s performance severely. In this paper, we propose a redundancy algorithm, data incremental parity algorithm (DIP, which employs HS-RAID to minimize the write penalty and improves the performance and reliability of the storage systems. The experimental results show that HS-RAID2 (HS-RAID with DIP is faster and has higher reliability than HS-RAID remarkably.

  19. Comprehensive Prediction of Large-height Swell-like Waves in East Coast of Korea

    Science.gov (United States)

    Kwon, S. J.; Lee, C.; Ahn, S. J.; Kim, H. K.

    2014-12-01

    There have been growing interests in the large-height swell-like wave (LSW) in the east coast of Korea because such big waves have caused human victims as well as damages to facilities such as breakwaters in the coast. The LSW was found to be generated due to an atmospherically great valley in the north area of the East Sea and then propagate long distance to the east coast of Korea in prominently southwest direction (Oh et al., 2010).In this study, we will perform two methods, real-time data based and numerical-model based predictions in order to predict the LSW in the east coast of Korea. First, the real-time data based prediction method uses information which is collected by the directional wave gauge installed near Sokcho. Using the wave model SWAN (Booij et al., 1999) and the wave ray method (Munk and Arthur, 1952), we will estimate wave data in open sea from the real-time data and predict the travel time of LSW from the measurement site (near Sokcho) to several target points in the east coast of Korea. Second, the numerical-model based method uses three different numerical models; WW3 in deep water, SWAN in shallow water, and CADMAS-SURF for wave run-up (CDIT). The surface winds from the 72 hours prediction system of NCEP (National Centers for Environmental Prediction) GFS (Global Forecast System) will be inputted in finer grids after interpolating these in certain domains of WW3 and SWAN models. The significant wave heights and peak wave directions predicted by the two methods will be compared to the measured data of LSW at several target points near the coasts. Further, the prediction method will be improved using more measurement sites which will be installed in the future. ReferencesBooij, N., Ris, R.C., and Holthuijsen, L.H. (1999). A third-generation wave model for coastal regions 1. Model description and validation. J. of Geophysical Research, 103(C4), 7649-7666.Munk, W.H. and Arthur, R.S. (1952). Gravity Waves. 13. Wave Intensity along a Refracted Ray

  20. A simple extension of “An alternative approach to sea surface aerodynamic roughness” by Zhiqiu Gao, Qing Wang, and Shouping Wang

    Science.gov (United States)

    Gao, Zhiqiu; Wang, Linlin; Bi, Xueyan; Song, Qingtao; Gao, Yuchao

    2012-08-01

    Based on the data previously collected during the Humidity Exchange over the Sea Main Experiment (HEXMAX), the methods used to parameterize aerodynamic roughness (z0), friction velocity (u*), and the neutral drag coefficient (CDN) under moderate wind speed conditions originally proposed by Gao et al. (2006) were extended by using the nondimensional significant wave height (gHs/u*2 or gHs/U10N2) instead of wave age (cp/u* or cp/U10N), where g is the acceleration of gravity, Hs is the significant wave height, U10Nis the horizontal wind speed at 10-m height under the neutral atmospheric condition, andcp is the phase velocity of the peak wave spectrum. The results show (1) u* = 0.024U10N(gHs/U10N2)-1/4, (2) z0 = 10 × exp[-4.797(gHs/u*2)1/6] or z0 = 10 × exp[-16.613(gHs/U10N2)1/4], and (3) CDN = 0.007(gHs/u*2)-1/3 or CDN = 5.76 × 10-4(gHs/U10N2)-1/2. The present parameterization schemes were experimentally tested.

  1. Extreme wind-wave modeling and analysis in the south Atlantic ocean

    Science.gov (United States)

    Campos, R. M.; Alves, J. H. G. M.; Guedes Soares, C.; Guimaraes, L. G.; Parente, C. E.

    2018-04-01

    A set of wave hindcasts is constructed using two different types of wind calibration, followed by an additional test retuning the input source term Sin in the wave model. The goal is to improve the simulation in extreme wave events in the South Atlantic Ocean without compromising average conditions. Wind fields are based on Climate Forecast System Reanalysis (CFSR/NCEP). The first wind calibration applies a simple linear regression model, with coefficients obtained from the comparison of CFSR against buoy data. The second is a method where deficiencies of the CFSR associated with severe sea state events are remedied, whereby "defective" winds are replaced with satellite data within cyclones. A total of six wind datasets forced WAVEWATCH-III and additional three tests with modified Sin in WAVEWATCH III lead to a total of nine wave hindcasts that are evaluated against satellite and buoy data for ambient and extreme conditions. The target variable considered is the significant wave height (Hs). The increase of sea-state severity shows a progressive increase of the hindcast underestimation which could be calculated as a function of percentiles. The wind calibration using a linear regression function shows similar results to the adjustments to Sin term (increase of βmax parameter) in WAVEWATCH-III - it effectively reduces the average bias of Hs but cannot avoid the increase of errors with percentiles. The use of blended scatterometer winds within cyclones could reduce the increasing wave hindcast errors mainly above the 93rd percentile and leads to a better representation of Hs at the peak of the storms. The combination of linear regression calibration of non-cyclonic winds with scatterometer winds within the cyclones generated a wave hindcast with small errors from calm to extreme conditions. This approach led to a reduction of the percentage error of Hs from 14% to less than 8% for extreme waves, while also improving the RMSE.

  2. Estimation of design wave heights based on exterme value statistics for Kakinada coast, Bay of Bengal

    Digital Repository Service at National Institute of Oceanography (India)

    Chandramohan, P.; Nayak, B.U.; Raju, N.S.N.

    Statistical analyses for longterm distribution of significant wave heights were performed using Lognormal, Weibull, Gumbel and Fretcher distributions for waves measured off Kakinada, Andhra Pradesh, India from June 1983 to May 1984. Fretcher...

  3. Performance of a data-driven technique to changes in wave height and its effect on beach response

    Directory of Open Access Journals (Sweden)

    Jose M. Horrillo-Caraballo

    2016-01-01

    Full Text Available In this study the medium-term response of beach profiles was investigated at two sites: a gently sloping sandy beach and a steeper mixed sand and gravel beach. The former is the Duck site in North Carolina, on the east coast of the USA, which is exposed to Atlantic Ocean swells and storm waves, and the latter is the Milford-on-Sea site at Christchurch Bay, on the south coast of England, which is partially sheltered from Atlantic swells but has a directionally bimodal wave exposure. The data sets comprise detailed bathymetric surveys of beach profiles covering a period of more than 25 years for the Duck site and over 18 years for the Milford-on-Sea site. The structure of the data sets and the data-driven methods are described. Canonical correlation analysis (CCA was used to find linkages between the wave characteristics and beach profiles. The sensitivity of the linkages was investigated by deploying a wave height threshold to filter out the smaller waves incrementally. The results of the analysis indicate that, for the gently sloping sandy beach, waves of all heights are important to the morphological response. For the mixed sand and gravel beach, filtering the smaller waves improves the statistical fit and it suggests that low-height waves do not play a primary role in the medium-term morphological response, which is primarily driven by the intermittent larger storm waves.

  4. Auto-correlation analysis of wave heights in the Bay of Bengal

    Indian Academy of Sciences (India)

    Time series observations of significant wave heights in the Bay of Bengal were subjected to auto- correlation analysis to determine temporal variability scale. The analysis indicates an exponen- tial fall of auto-correlation in the first few hours with a decorrelation time scale of about six hours. A similar figure was found earlier ...

  5. Performance of a data-driven technique applied to changes in wave height and its effect on beach response

    Directory of Open Access Journals (Sweden)

    José M. Horrillo-Caraballo

    2016-01-01

    Full Text Available In this study the medium-term response of beach profiles was investigated at two sites: a gently sloping sandy beach and a steeper mixed sand and gravel beach. The former is the Duck site in North Carolina, on the east coast of the USA, which is exposed to Atlantic Ocean swells and storm waves, and the latter is the Milford-on-Sea site at Christchurch Bay, on the south coast of England, which is partially sheltered from Atlantic swells but has a directionally bimodal wave exposure. The data sets comprise detailed bathymetric surveys of beach profiles covering a period of more than 25 years for the Duck site and over 18 years for the Milford-on-Sea site. The structure of the data sets and the data-driven methods are described. Canonical correlation analysis (CCA was used to find linkages between the wave characteristics and beach profiles. The sensitivity of the linkages was investigated by deploying a wave height threshold to filter out the smaller waves incrementally. The results of the analysis indicate that, for the gently sloping sandy beach, waves of all heights are important to the morphological response. For the mixed sand and gravel beach, filtering the smaller waves improves the statistical fit and it suggests that low-height waves do not play a primary role in the medium-term morphological response, which is primarily driven by the intermittent larger storm waves.

  6. Does Shoe Collar Height Influence Ankle Joint Kinematics and Kinetics in Sagittal Plane Maneuvers?

    Directory of Open Access Journals (Sweden)

    Yang Yang, Ying Fang, Xini Zhang, Junliang He, Weijie Fu

    2017-12-01

    Full Text Available The Objective of the study is to investigate the effects of basketball shoes with different collar heights on ankle kinematics and kinetics and athletic performance in different sagittal plane maneuvers. Twelve participants who wore high-top and low-top basketball shoes (hereafter, HS and LS, respectively performed a weight-bearing dorsiflexion (WB-DF maneuver, drop jumps (DJs, and lay-up jumps (LJs. Their sagittal plane kinematics and ground reaction forces were recorded using the Vicon motion capture system and Kistler force plates simultaneously. Moreover, ankle dorsiflexion and plantarflexion angles, moment, power, stiffness, and jump height were calculated. In the WB-DF test, the peak ankle dorsiflexion angle (p = 0.041 was significantly smaller in HS than in LS. Additionally, the peak ankle plantarflexion moment (p = 0.028 and power (p = 0.022 were significantly lower in HS than in LS during LJs but not during DJs. In both jumping maneuvers, no significant differences were found in the jump height or ankle kinematics between the two shoe types. According to the WB-DF test, increasing shoe collar height can effectively reduce the ankle range of motion in the sagittal plane. Although the HS did not restrict the flexion–extension performance of the ankle joint during two jumping maneuvers, an increased shoe collar height can reduce peak ankle plantarflexion moment and peak power during the push-off phase in LJs. Therefore, a higher shoe collar height should be used to circumvent effects on the partial kinetics of the ankle joint in the sagittal plane.

  7. Does Shoe Collar Height Influence Ankle Joint Kinematics and Kinetics in Sagittal Plane Maneuvers?

    Science.gov (United States)

    Yang, Yang; Fang, Ying; Zhang, Xini; He, Junliang; Fu, Weijie

    2017-12-01

    The Objective of the study is to investigate the effects of basketball shoes with different collar heights on ankle kinematics and kinetics and athletic performance in different sagittal plane maneuvers. Twelve participants who wore high-top and low-top basketball shoes (hereafter, HS and LS, respectively) performed a weight-bearing dorsiflexion (WB-DF) maneuver, drop jumps (DJs), and lay-up jumps (LJs). Their sagittal plane kinematics and ground reaction forces were recorded using the Vicon motion capture system and Kistler force plates simultaneously. Moreover, ankle dorsiflexion and plantarflexion angles, moment, power, stiffness, and jump height were calculated. In the WB-DF test, the peak ankle dorsiflexion angle (p = 0.041) was significantly smaller in HS than in LS. Additionally, the peak ankle plantarflexion moment (p = 0.028) and power (p = 0.022) were significantly lower in HS than in LS during LJs but not during DJs. In both jumping maneuvers, no significant differences were found in the jump height or ankle kinematics between the two shoe types. According to the WB-DF test, increasing shoe collar height can effectively reduce the ankle range of motion in the sagittal plane. Although the HS did not restrict the flexion-extension performance of the ankle joint during two jumping maneuvers, an increased shoe collar height can reduce peak ankle plantarflexion moment and peak power during the push-off phase in LJs. Therefore, a higher shoe collar height should be used to circumvent effects on the partial kinetics of the ankle joint in the sagittal plane.

  8. Wave Height Estimation from Shadowing Based on the Acquired X-Band Marine Radar Images in Coastal Area

    Directory of Open Access Journals (Sweden)

    Yanbo Wei

    2017-08-01

    Full Text Available In this paper, the retrieving significant wave height from X-band marine radar images based on shadow statistics is investigated, since the retrieving accuracy can not be seriously affected by environmental factors and the method has the advantage of without any external reference to calibrate. However, the accuracy of the significant wave height estimated from the radar image acquired at the near-shore area is not ideal. To solve this problem, the effect of water depth is considered in the theoretical derivation of estimated wave height based on the sea surface slope. And then, an improved retrieving algorithm which is suitable for both in deep water area and shallow water area is developed. In addition, the radar data are sparsely processed in advance in order to achieve high quality edge image for the requirement of shadow statistic algorithm, since the high resolution radar images will lead to angle-blurred for the image edge detection and time-consuming in the estimation of sea surface slope. The data acquired from Pingtan Test Base in Fujian Province were used to verify the effectiveness of the proposed algorithm. The experimental results demonstrate that the improved method which takes into account the water depth is more efficient and effective and has better performance for retrieving significant wave height in the shallow water area, compared to the in situ buoy data as the ground truth and that of the existing shadow statistic method.

  9. Does Shoe Collar Height Influence Ankle Joint Kinematics and Kinetics in Sagittal Plane Maneuvers?

    Science.gov (United States)

    Yang, Yang; Fang, Ying; Zhang, Xini; He, Junliang; Fu, Weijie

    2017-01-01

    The Objective of the study is to investigate the effects of basketball shoes with different collar heights on ankle kinematics and kinetics and athletic performance in different sagittal plane maneuvers. Twelve participants who wore high-top and low-top basketball shoes (hereafter, HS and LS, respectively) performed a weight-bearing dorsiflexion (WB-DF) maneuver, drop jumps (DJs), and lay-up jumps (LJs). Their sagittal plane kinematics and ground reaction forces were recorded using the Vicon motion capture system and Kistler force plates simultaneously. Moreover, ankle dorsiflexion and plantarflexion angles, moment, power, stiffness, and jump height were calculated. In the WB-DF test, the peak ankle dorsiflexion angle (p = 0.041) was significantly smaller in HS than in LS. Additionally, the peak ankle plantarflexion moment (p = 0.028) and power (p = 0.022) were significantly lower in HS than in LS during LJs but not during DJs. In both jumping maneuvers, no significant differences were found in the jump height or ankle kinematics between the two shoe types. According to the WB-DF test, increasing shoe collar height can effectively reduce the ankle range of motion in the sagittal plane. Although the HS did not restrict the flexion–extension performance of the ankle joint during two jumping maneuvers, an increased shoe collar height can reduce peak ankle plantarflexion moment and peak power during the push-off phase in LJs. Therefore, a higher shoe collar height should be used to circumvent effects on the partial kinetics of the ankle joint in the sagittal plane. Key points An increased shoe collar height effectively reduced ankle joint ROM in the sagittal plane in weight-bearing dorsiflexion maneuver. Shoe collar height did not affect sagittal plane ankle kinematics and had no effect on performance during realistic jumping. Shoe collar height can affect the ankle plantarflexion torque and peak power during the push-off phase in lay-up jump. PMID:29238255

  10. Progress Report on the GROWTH (GNSS Reflectometry for Ocean Waves, Tides, and Height) Research Project

    Science.gov (United States)

    Kitazawa, Y.; Ichikawa, K.; Akiyama, H.; Ebinuma, T.; Isoguchi, O.; Kimura, N.; Konda, M.; Kouguchi, N.; Tamura, H.; Tomita, H.; Yoshikawa, Y.; Waseda, T.

    2016-12-01

    Global Navigation Satellite Systems (GNSS), such as GPS is a system of satellites that provide autonomous geo-spatial positioning with global coverage. It allows small electronic receivers to determine their location to high precision using radio signals transmitted from satellites, GNSS reflectometry (GNSS-R) involves making measurements from the reflections from the Earth of navigation signals from GNSS satellites. Reflected signals from sea surface are considered that those are useful to observe sea state and sea surface height. We have started a research program for GNSS-R applications on oceanographic observations under the contract with MEXT (Ministry of Education Culture, Sports, Science and Technology, JAPAN) and launched a Japanese research consortium, GROWTH (GNSS Reflectometry for Ocean Waves, Tides, and Height). It is aiming to evaluate the capabilities of GNSS-R observations for oceanographic phenomena with different time scales, such as ocean waves (1/10 to tens of seconds), tides (one or half days), and sea surface dynamic height (a few days to years). In situ observations of ocean wave spectrum, wind speed vertical profile, and sea surface height will be quantitatively compared with equivalent estimates from simultaneous GNSS-R measurements. The GROWTH project will utilize different types of observation platforms; marine observation towers (about 20 m height), multi-copters (about 100 to 150 m height), and much higher-altitude CYGNSS data. Cross-platform data, together with in situ oceanographic observations, will be compared after adequate temporal averaging that accounts differences of the footprint sizes and temporal and spatial scales of oceanographic phenomena. This paper will provide overview of the GROWTH project, preliminary test results, obtained by the multi-sensor platform at observation towers, suggest actual footprint sizes and identification of swell. Preparation status of a ground station which will be supplied to receive CYGNSS data

  11. A hidden service model based on HS-HS anonymous network

    Science.gov (United States)

    Meng, Yitong; Zhao, Xing; Fei, Jinlong; Zhu, Yuefei

    2017-10-01

    The Hidden Service provided by Tor anonymous network can effectively protect the anonymity and security of the Hidden server, this article through the analysis of the data packet structure of Tor, three jump transmission mechanism and link establishment protocol and Hidden Service communication process, in view of the Hidden node number too much, link building Service for too long and too redundant link problem. An improved hidden service model HS-HS is proposed that incorporating multiple transmission link and reuse, and at the same time will be important transit point for reuse protection link anonymity, through the ExperimenTor simulation environment test, verify the improved model of HS-HS can be more effective in guarantee anonymity and security, improve the overall efficiency of data transmission, to meet the needs of today's anonymous service.

  12. Corrections for the effects of significant wave height and attitude on Geosat radar altimeter measurements

    Science.gov (United States)

    Hayne, G. S.; Hancock, D. W., III

    1990-01-01

    Range estimates from a radar altimeter have biases which are a function of the significant wave height (SWH) and the satellite attitude angle (AA). Based on results of prelaunch Geosat modeling and simulation, a correction for SWH and AA was already applied to the sea-surface height estimates from Geosat's production data processing. By fitting a detailed model radar return waveform to Geosat waveform sampler data, it is possible to provide independent estimates of the height bias, the SWH, and the AA. The waveform fitting has been carried out for 10-sec averages of Geosat waveform sampler data over a wide range of SWH and AA values. The results confirm that Geosat sea-surface-height correction is good to well within the original dm-level specification, but that an additional height correction can be made at the level of several cm.

  13. Observational and Dynamical Wave Climatologies. VOS vs Satellite Data

    Science.gov (United States)

    Grigorieva, Victoria; Badulin, Sergei; Chernyshova, Anna

    2013-04-01

    The understanding physics of wind-driven waves is crucially important for fundamental science and practical applications. This is why experimental efforts are targeted at both getting reliable information on sea state and elaborating effective tools of the sea wave forecasting. The global Visual Wave Observations and satellite data from the GLOBWAVE project of the European Space Agency are analyzed in the context of these two viewpoints. Within the first "observational" aspect we re-analyze conventional climatologies of all basic wave parameters for the last decades [5]. An alternative "dynamical" climatology is introduced as a tool of prediction of dynamical features of sea waves on global scales. The features of wave dynamics are studied in terms of one-parametric dependencies of wave heights on wave periods following the theoretical concept of self-similar wind-driven seas [3, 1, 4] and recently proposed approach to analysis of Voluntary Observing Ship (VOS) data [2]. Traditional "observational" climatologies based on VOS and satellite data collections demonstrate extremely consistent pictures for significant wave heights and dominant periods. On the other hand, collocated satellite and VOS data show significant differences in wave heights, wind speeds and, especially, in wave periods. Uncertainties of visual wave observations can explain these differences only partially. We see the key reason of this inconsistency in the methods of satellite data processing which are based on formal application of data interpolation methods rather than on up-to-date physics of wind-driven waves. The problem is considered within the alternative climatology approach where dynamical criteria of wave height-to-period linkage are used for retrieving wave periods and constructing physically consistent dynamical climatology. The key dynamical parameter - exponent R of one-parametric dependence Hs ~ TR shows dramatically less pronounced latitudinal dependence as compared to observed Hs

  14. A numerical study on the effects of wave-current-surge interactions on the height and propagation of sea surface waves in Charleston Harbor during Hurricane Hugo 1989

    Science.gov (United States)

    Liu, Huiqing; Xie, Lian

    2009-06-01

    The effects of wave-current interactions on ocean surface waves induced by Hurricane Hugo in and around the Charleston Harbor and its adjacent coastal waters are examined by using a three-dimensional (3D) wave-current coupled modeling system. The 3D storm surge modeling component of the coupled system is based on the Princeton Ocean Model (POM), the wave modeling component is based on the third generation wave model, Simulating WAves Nearshore (SWAN), and the inundation model is adopted from [Xie, L., Pietrafesa, L. J., Peng, M., 2004. Incorporation of a mass-conserving inundation scheme into a three-dimensional storm surge model. J. Coastal Res., 20, 1209-1223]. The results indicate that the change of water level associated with the storm surge is the primary cause for wave height changes due to wave-surge interaction. Meanwhile, waves propagating on top of surge cause a feedback effect on the surge height by modulating the surface wind stress and bottom stress. This effect is significant in shallow coastal waters, but relatively small in offshore deep waters. The influence of wave-current interaction on wave propagation is relatively insignificant, since waves generally propagate in the direction of the surface currents driven by winds. Wave-current interactions also affect the surface waves as a result of inundation and drying induced by the storm. Waves break as waters retreat in regions of drying, whereas waves are generated in flooded regions where no waves would have occurred without the flood water.

  15. [P wave dispersion increased in childhood depending on blood pressure, weight, height, and cardiac structure and function].

    Science.gov (United States)

    Chávez-González, Elibet; González-Rodríguez, Emilio; Llanes-Camacho, María Del Carmen; Garí-Llanes, Merlin; García-Nóbrega, Yosvany; García-Sáez, Julieta

    2014-01-01

    Increased P wave dispersion are identified as a predictor of atrial fibrillation. There are associations between hypertension, P wave dispersion, constitutional and echocardiographic variables. These relationships have been scarcely studied in pediatrics. The aim of this study was to determine the relationship between P wave dispersion, blood pressure, echocardiographic and constitutional variables, and determine the most influential variables on P wave dispersion increases in pediatrics. In the frame of the PROCDEC II project, children from 8 to 11 years old, without known heart conditions were studied. Arterial blood pressure was measured in all the children; a 12-lead surface electrocardiogram and an echocardiogram were done as well. Left ventricular mass index mean values for normotensive (25.91±5.96g/m(2.7)) and hypertensive (30.34±8.48g/m(2.7)) showed significant differences P=.000. When we add prehypertensive and hypertensive there are 50.38% with normal left ventricular mass index and P wave dispersion was increased versus 13.36% of normotensive. Multiple regression demonstrated that the mean blood pressure, duration of A wave of mitral inflow, weight and height have a value of r=0.88 as related to P wave dispersion. P wave dispersion is increased in pre- and hypertensive children compared to normotensive. There are pre- and hypertensive patients with normal left ventricular mass index and increased P wave dispersion. Mean arterial pressure, duration of the A wave of mitral inflow, weight and height are the variables with the highest influence on increased P wave dispersion. Copyright © 2013 Instituto Nacional de Cardiología Ignacio Chávez. Published by Masson Doyma México S.A. All rights reserved.

  16. CMIP5-based global wave climate projections including the entire Arctic Ocean

    Science.gov (United States)

    Casas-Prat, M.; Wang, X. L.; Swart, N.

    2018-03-01

    This study presents simulations of the global ocean wave climate corresponding to the surface winds and sea ice concentrations as simulated by five CMIP5 (Coupled Model Intercomparison Project Phase 5) climate models for the historical (1979-2005) and RCP8.5 scenario future (2081-2100) periods. To tackle the numerical complexities associated with the inclusion of the North Pole, the WAVEWATCH III (WW3) wave model was used with a customized unstructured Spherical Multi-Cell grid of ∼100 km offshore and ∼50 km along coastlines. The climate model simulated wind and sea ice data, and the corresponding WW3 simulated wave data, were evaluated against reanalysis and hindcast data. The results show that all the five sets of wave simulations projected lower waves in the North Atlantic, corresponding to decreased surface wind speeds there in the warmer climate. The selected CMIP5 models also consistently projected an increase in the surface wind speed in the Southern Hemisphere (SH) mid-high latitudes, which translates in an increase in the WW3 simulated significant wave height (Hs) there. The higher waves are accompanied with increased peak wave period and increased wave age in the East Pacific and Indian Oceans, and a significant counterclockwise rotation in the mean wave direction in the Southern Oceans. The latter is caused by more intense waves from the SH traveling equatorward and developing into swells. Future wave climate in the Arctic Ocean in summer is projected to be predominantly of mixed sea states, with the climatological mean of September maximum Hs ranging mostly 3-4 m. The new waves approaching Arctic coasts will be less fetch-limited as ice retreats since a predominantly southwards mean wave direction is projected in the surrounding seas.

  17. Wave Dragon Wave Energy Converters Used as Coastal Protection

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen Harck; Andersen, Thomas Lykke; Kofoed, Jens Peter

    2011-01-01

    This paper deals with wave energy converters used to reduce the wave height along shorelines. For this study the Wave Dragon wave energy converter is chosen. The wave height reduction from a single device has been evaluated from physical model tests in scale 1:51.8 of the 260 x 150 m, 24 kW/m model...... Spain, to evaluate the potential for reducing wave heights close the shore by means of Wave Dragons....

  18. Managing Information Uncertainty in Wave Height Modeling for the Offshore Structural Analysis through Random Set

    Directory of Open Access Journals (Sweden)

    Keqin Yan

    2017-01-01

    Full Text Available This chapter presents a reliability study for an offshore jacket structure with emphasis on the features of nonconventional modeling. Firstly, a random set model is formulated for modeling the random waves in an ocean site. Then, a jacket structure is investigated in a pushover analysis to identify the critical wave direction and key structural elements. This is based on the ultimate base shear strength. The selected probabilistic models are adopted for the important structural members and the wave direction is specified in the weakest direction of the structure for a conservative safety analysis. The wave height model is processed in a P-box format when it is used in the numerical analysis. The models are applied to find the bounds of the failure probabilities for the jacket structure. The propagation of this wave model to the uncertainty in results is investigated in both an interval analysis and Monte Carlo simulation. The results are compared in context of information content and numerical accuracy. Further, the failure probability bounds are compared with the conventional probabilistic approach.

  19. Econometric analysis of the changing effects in wind strength and significant wave height on the probability of casualty in shipping.

    Science.gov (United States)

    Knapp, Sabine; Kumar, Shashi; Sakurada, Yuri; Shen, Jiajun

    2011-05-01

    This study uses econometric models to measure the effect of significant wave height and wind strength on the probability of casualty and tests whether these effects changed. While both effects are in particular relevant for stability and strength calculations of vessels, it is also helpful for the development of ship construction standards in general to counteract increased risk resulting from changing oceanographic conditions. The authors analyzed a unique dataset of 3.2 million observations from 20,729 individual vessels in the North Atlantic and Arctic regions gathered during the period 1979-2007. The results show that although there is a seasonal pattern in the probability of casualty especially during the winter months, the effect of wind strength and significant wave height do not follow the same seasonal pattern. Additionally, over time, significant wave height shows an increasing effect in January, March, May and October while wind strength shows a decreasing effect, especially in January, March and May. The models can be used to simulate relationships and help understand the relationships. This is of particular interest to naval architects and ship designers as well as multilateral agencies such as the International Maritime Organization (IMO) that establish global standards in ship design and construction. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Modelling the effect of suspended load transport and tidal asymmetry on the equilibrium tidal sand wave height

    NARCIS (Netherlands)

    van Gerwen, W.; Borsje, Bastiaan Wijnand; Damveld, Johan Hendrik; Hulscher, Suzanne J.M.H.

    2018-01-01

    Tidal sand waves are rhythmic bed forms found in shallow sandy coastal seas, reaching heights up to ten meters and migration rates of several meters per year. Because of their dynamic behaviour, unravelling the physical processes behind the growth of these bed forms is of particular interest to

  1. Trends of wave height and period in the Central Arabian Sea from 1996 to 2012: A study based on satellite altimeter data

    Digital Repository Service at National Institute of Oceanography (India)

    Hithin, N.K.; SanilKumar, V.; Shanas, P.R.

    The variability of annual maximum and annual mean significant wave height (SWH) and wave period in the Central Arabian Sea is studied using satellite altimeter data from 1996 to 2012 at a deep water (water depth~3500 m) buoy location (15.5°N, 69...

  2. Italian Validation of Homophobia Scale (HS).

    Science.gov (United States)

    Ciocca, Giacomo; Capuano, Nicolina; Tuziak, Bogdan; Mollaioli, Daniele; Limoncin, Erika; Valsecchi, Diana; Carosa, Eleonora; Gravina, Giovanni L; Gianfrilli, Daniele; Lenzi, Andrea; Jannini, Emmanuele A

    2015-09-01

    The Homophobia Scale (HS) is a valid tool to assess homophobia. This test is self-reporting, composed of 25 items, which assesses a total score and three factors linked to homophobia: behavior/negative affect, affect/behavioral aggression, and negative cognition. The aim of this study was to validate the HS in the Italian context. An Italian translation of the HS was carried out by two bilingual people, after which an English native translated the test back into the English language. A psychologist and sexologist checked the translated items from a clinical point of view. We recruited 100 subjects aged18-65 for the Italian validation of the HS. The Pearson coefficient and Cronbach's α coefficient were performed to test the test-retest reliability and internal consistency. A sociodemographic questionnaire including the main information as age, geographic distribution, partnership status, education, religious orientation, and sex orientation was administrated together with the translated version of HS. The analysis of the internal consistency showed an overall Cronbach's α coefficient of 0.92. In the four domains, the Cronbach's α coefficient was 0.90 in behavior/negative affect, 0.94 in affect/behavioral aggression, and 0.92 in negative cognition, whereas in the total score was 0.86. The test-retest reliability showed the following results: the HS total score was r = 0.93 (P cognition was r = 0.75 (P validation of the HS revealed the use of this self-report test to have good psychometric properties. This study offers a new tool to assess homophobia. In this regard, the HS can be introduced into the clinical praxis and into programs for the prevention of homophobic behavior.

  3. Wave Transformation for International Hub Port Planning (Transformasi Gelombang untuk Perencanaan Pelabuhan Hub Internasional

    Directory of Open Access Journals (Sweden)

    Denny Nugroho Sugianto

    2015-02-01

    archipelagic countries in the world, therefore port has vital role in economic development. Port is not just as a complement to the infrastructure, but it must be planned and managed properly and attention to the dynamics of marine phenomena such as ocean wave patterns. Ocean wave data become important factors in planning coastal building, since it is influenced by wave height, tides and waves transformation. The purpose of this study was to analyse characteristic and forms wave transformations for planning of international hub port at Kuala Tanjung, Baru Bara District North Sumatra. This port is one of two Indonesian government's plan in the development of international hub port. Quantitative method was used in this study by statistical calculations and mathematical modeling with hydrodinamic modules and spectral wave to determine the direction of wave propagation and transformation. Results show that based on ECMWF data during 1999-June 2014, known significant wave height (Hs maximum of 1.69 m and maximum period (Ts of 8 secs. The classification wave characteristics iswave transition (d.L-1: 0.27–0.48 and by the period are classified as gravitational waves. Wave transformation occurs due to the soaling, withKs 0.93–0.98 and the wave refraction Kr 0.97–0.99. Whereas Hb of 1.24 meters anddb 1.82 meters. The effectiveness of the design of the terminal building at the Port of Kuala Tanjung overall for the season amounted to 79.8%, which is quite effective in reducing the wave. Keywords: wave transformation, wave height and period, Port of Kuala Tanjung

  4. Sea state indices for a coastal strait

    Science.gov (United States)

    Gemmrich, Johannes; Dewey, Richard

    2017-04-01

    The Strait of Georgia at the west coast of Canada is an enclosed coastal strait, about 250km long and 25 to 50 km wide, with great socio-economic importance. Regular freighter traffic, ferry services, commercial and sport fisheries, and recreational boating, makes the area one of the busiest marine areas in the world. Waves in SoG are generally small, with the median value of the significant wave height Hs=0.3m. However, strong outflows off the mountainous terrain can generate significant wave heights Hs > 2.5m, with high spatial and temporal variability. In addition, strong tidal currents and the Fraser River outflow generate localized regions of steep and breaking waves that are of particular concern. We have implemented the Wavewatch III model at 500m-resolution, forced by Environment Canada's high resolution atmospheric model winds and currents from the UBC NEMO implementation of the Salish Sea. The final output combines GIS layers of the predicted wave field (Hs, dominant wave length and direction), the modeled wind field and currents, observed currents from a set of CODAR systems, and a sea state index that highlights regions of potentially steep and dangerous waves.

  5. Decadal variability of extreme wave height representing storm severity in the northeast Atlantic and North Sea since the foundation of the Royal Society

    Science.gov (United States)

    Santo, H.; Taylor, P. H.; Gibson, R.

    2016-09-01

    Long-term estimation of extreme wave height remains a key challenge because of the short duration of available wave data, and also because of the possible impact of climate variability on ocean waves. Here, we analyse storm-based statistics to obtain estimates of extreme wave height at locations in the northeast Atlantic and North Sea using the NORA10 wave hindcast (1958-2011), and use a 5 year sliding window to examine temporal variability. The decadal variability is correlated to the North Atlantic oscillation and other atmospheric modes, using a six-term predictor model incorporating the climate indices and their Hilbert transforms. This allows reconstruction of the historic extreme climate back to 1661, using a combination of known and proxy climate indices. Significant decadal variability primarily driven by the North Atlantic oscillation is observed, and this should be considered for the long-term survivability of offshore structures and marine renewable energy devices. The analysis on wave climate reconstruction reveals that the variation of the mean, 99th percentile and extreme wave climates over decadal time scales for locations close to the dominant storm tracks in the open North Atlantic are comparable, whereas the wave climates for the rest of the locations including the North Sea are rather different.

  6. Seasonal and height variation of gravity wave activities observed by a meteor radar at King Sejong Station (62°S, 57°W), Antarctica

    Science.gov (United States)

    Kim, Y.; Lee, C.; Kim, J.; Choi, J.; Jee, G.

    2010-12-01

    We have analyzed wind data from individual meteor echoes detected by a meteor radar at King Sejong Station, Antarctica to measure gravity wave activity in the mesopause region. Wind data in the meteor altitudes has been obtained routinely by the meteor radar since its installation in March 2007. The mean variances in the wind data that were filtered for large scale motions (mean winds and tides) can be regarded as the gravity wave activity. Monthly mean gravity wave activities show strong seasonal and height dependences in the altitude range of 80 to 100 km. The gravity wave activities except summer monotonically increase with altitude, which is expected since decreasing atmospheric densities cause wave amplitudes to increase. During summer (Dec. - Feb.) the height profiles of gravity wave activities show a minimum near 90 - 95 km, which may be due to different zonal wind and strong wind shear near 80 - 95 km. Our gravity wave activities are generally stronger than those of the Rothera station, implying sensitive dependency on location. The difference may be related to gravity wave sources in the lower atmosphere near Antarctic vortex.

  7. Synthesizing Waves from Animated Height Fields

    DEFF Research Database (Denmark)

    Nielsen, Michael Bang; Söderström, Andreas; Bridson, Robert

    2013-01-01

    Computer animated ocean waves for feature films are typically carefully choreographed to match the vision of the director and to support the telling of the story. The rough shape of these waves is established in the previsualization (previs) stage, where artists use a variety of modeling tools wi...... of deep water waves), and compute a physically reasonable velocity field of the water analytically. These properties are demonstrated with several examples, including a previs scene from a visual effects production environment....

  8. Italian Validation of Homophobia Scale (HS)

    OpenAIRE

    Ciocca, Giacomo; Capuano, Nicolina; Tuziak, Bogdan; Mollaioli, Daniele; Limoncin, Erika; Valsecchi, Diana; Carosa, Eleonora; Gravina, Giovanni L.; Gianfrilli, Daniele; Lenzi, Andrea; Jannini, Emmanuele A.

    2015-01-01

    Introduction: The Homophobia Scale (HS) is a valid tool to assess homophobia. This test is self‐reporting, composed of 25 items, which assesses a total score and three factors linked to homophobia: behavior/negative affect, affect/behavioral aggression, and negative cognition. Aim: The aim of this study was to validate the HS in the Italian context. Methods: An Italian translation of the HS was carried out by two bilingual people, after which an English native translated the test back i...

  9. Variations in return value estimate of ocean surface waves - a study based on measured buoy data and ERA-Interim reanalysis data

    Science.gov (United States)

    Muhammed Naseef, T.; Sanil Kumar, V.

    2017-10-01

    An assessment of extreme wave characteristics during the design of marine facilities not only helps to ensure their safety but also assess the economic aspects. In this study, return levels of significant wave height (Hs) for different periods are estimated using the generalized extreme value distribution (GEV) and generalized Pareto distribution (GPD) based on the Waverider buoy data spanning 8 years and the ERA-Interim reanalysis data spanning 38 years. The analysis is carried out for wind-sea, swell and total Hs separately for buoy data. Seasonality of the prevailing wave climate is also considered in the analysis to provide return levels for short-term activities in the location. The study shows that the initial distribution method (IDM) underestimates return levels compared to GPD. The maximum return levels estimated by the GPD corresponding to 100 years are 5.10 m for the monsoon season (JJAS), 2.66 m for the pre-monsoon season (FMAM) and 4.28 m for the post-monsoon season (ONDJ). The intercomparison of return levels by block maxima (annual, seasonal and monthly maxima) and the r-largest method for GEV theory shows that the maximum return level for 100 years is 7.20 m in the r-largest series followed by monthly maxima (6.02 m) and annual maxima (AM) (5.66 m) series. The analysis is also carried out to understand the sensitivity of the number of observations for the GEV annual maxima estimates. It indicates that the variations in the standard deviation of the series caused by changes in the number of observations are positively correlated with the return level estimates. The 100-year return level results of Hs using the GEV method are comparable for short-term (2008 to 2016) buoy data (4.18 m) and long-term (1979 to 2016) ERA-Interim shallow data (4.39 m). The 6 h interval data tend to miss high values of Hs, and hence there is a significant difference in the 100-year return level Hs obtained using 6 h interval data compared to data at 0.5 h interval. The

  10. Italian Validation of Homophobia Scale (HS

    Directory of Open Access Journals (Sweden)

    Giacomo Ciocca, PsyD, PhD

    2015-09-01

    Conclusions: The Italian validation of the HS revealed the use of this self‐report test to have good psychometric properties. This study offers a new tool to assess homophobia. In this regard, the HS can be introduced into the clinical praxis and into programs for the prevention of homophobic behavior. Ciocca G, Capuano N, Tuziak B, Mollaioli D, Limoncin E, Valsecchi D, Carosa E, Gravina GL, Gianfrilli D, Lenzi A, and Jannini EA. Italian validation of Homophobia Scale (HS. Sex Med 2015;3:213–218.

  11. The impact of North Atlantic wind and cyclone trends on European precipitation and significant wave height in the Atlantic.

    Science.gov (United States)

    Trigo, Ricardo M; Valente, Maria A; Trigo, Isabel F; Miranda, Pedro M A; Ramos, Alexandre M; Paredes, Daniel; García-Herrera, Ricardo

    2008-12-01

    An analysis of the frequency of cyclones and surface wind velocity for the Euro-Atlantic sector is performed by means of an objective methodology. Monthly and seasonal trends of cyclones and wind speed magnitude are computed and trends between 1960 and 2000 evaluated. Results reveal a significant frequency decrease (increase) in the western Mediterranean (Greenland and Scandinavia), particularly in December, February, and March. Seasonal and monthly analysis of wind magnitude trends shows similar spatial patterns. We show that these changes in the frequency of low-pressure centers and the associated wind patterns are partially responsible for trends in the significant height of waves. Throughout the extended winter months (October-March), regions with positive (negative) wind magnitude trends, of up to 5 cm/s/year, often correspond to regions of positive (negative) significant wave height trends. The cyclone and wind speed trends computed for January-March are well matched by the corresponding trends in significant wave height, with February being the month with the highest trends (negative south of lat 50 degrees N up to -3 cm/year, and positive up to 5 cm/year just north of Scotland). Trends in European precipitation are assessed using the Climatic Research Unit data set. The results of the assessment emphasize the link with the corresponding tendencies of cyclone frequencies. Finally, it is shown that these changes are associated, to a large extent, with the preferred phases of major large-scale atmospheric circulation modes, particularly with the North Atlantic Oscillation, the eastern Atlantic pattern, and the Scandinavian pattern.

  12. Incident wave, infragravity wave, and non-linear low-frequency bore evolution across fringing coral reefs

    Science.gov (United States)

    Storlazzi, C. D.; Griffioen, D.; Cheriton, O. M.

    2016-12-01

    Coral reefs have been shown to significantly attenuate incident wave energy and thus provide protection for 100s of millions of people globally. To better constrain wave dynamics and wave-driven water levels over fringing coral reefs, a 4-month deployment of wave and tide gauges was conducted across two shore-normal transects on Roi-Namur Island and two transects on Kwajalein Island in the Republic of the Marshall Islands. At all locations, although incident wave (periods 250 s) heights on the outer reef flat just inshore of the zone of wave breaking, the infragravity wave heights generally equaled the incident wave heights by the middle of the reef flat and exceeded the incident wave heights on the inner reef flat by the shoreline. The infragravity waves generally were asymmetric, positively skewed, bore-like forms with incident-band waves riding the infragravity wave crest at the head of the bore; these wave packets have similar structure to high-frequency internal waves on an internal wave bore. Bore height was shown to scale with water depth, offshore wave height, and offshore wave period. For a given tidal elevation, with increasing offshore wave heights, such bores occurred more frequently on the middle reef flat, whereas they occurred less frequently on the inner reef flat. Skewed, asymmetric waves are known to drive large gradients in velocity and shear stress that can transport material onshore. Thus, a better understanding of these low-frequency, energetic bores on reef flats is critical to forecasting how coral reef-lined coasts may respond to sea-level rise and climate change.

  13. Evaluation and adjustment of altimeter measurement and numerical hindcast in wave height trend estimation in China's coastal seas

    Science.gov (United States)

    Li, Shuiqing; Guan, Shoude; Hou, Yijun; Liu, Yahao; Bi, Fan

    2018-05-01

    A long-term trend of significant wave height (SWH) in China's coastal seas was examined based on three datasets derived from satellite measurements and numerical hindcasts. One set of altimeter data were obtained from the GlobWave, while the other two datasets of numerical hindcasts were obtained from the third-generation wind wave model, WAVEWATCH III, forced by wind fields from the Cross-Calibrated Multi-Platform (CCMP) and NCEP's Climate Forecast System Reanalysis (CFSR). The mean and extreme wave trends were estimated for the period 1992-2010 with respect to the annual mean and the 99th-percentile values of SWH, respectively. The altimeter wave trend estimates feature considerable uncertainties owing to the sparse sampling rate. Furthermore, the extreme wave trend tends to be overestimated because of the increasing sampling rate over time. Numerical wave trends strongly depend on the quality of the wind fields, as the CCMP waves significantly overestimate the wave trend, whereas the CFSR waves tend to underestimate the trend. Corresponding adjustments were applied which effectively improved the trend estimates from the altimeter and numerical data. The adjusted results show generally increasing mean wave trends, while the extreme wave trends are more spatially-varied, from decreasing trends prevailing in the South China Sea to significant increasing trends mainly in the East China Sea.

  14. Experimental Studies on Wave Interactions of Partially Perforated Wall under Obliquely Incident Waves

    Directory of Open Access Journals (Sweden)

    Jong-In Lee

    2014-01-01

    Full Text Available This study presents wave height distribution in terms of stem wave evolution phenomena on partially perforated wall structures through three-dimensional laboratory experiments. The plain and partially perforated walls were tested to understand their effects on the stem wave evolution under the monochromatic and random wave cases with the various wave conditions, incident angle (from 10 to 40 degrees, and configurations of front and side walls. The partially perforated wall reduced the relative wave heights more effectively compared to the plain wall structure. Partially perforated walls with side walls showed a better performance in terms of wave height reduction compared to the structure without the side wall. Moreover, the relative wave heights along the wall were relatively small when the relative chamber width is large, within the range of the chamber width in this study. The wave spectra showed a frequency dependency of the wave energy dissipation. In most cases, the existence of side wall is a more important factor than the porosity of the front wall in terms of the wave height reduction even if the partially perforated wall was still effective compared to the plain wall.

  15. Further Development of HS Field Theory

    Science.gov (United States)

    Abdurrahman, Abdulmajeed; Faridani, Jacqueline; Gassem, Mahmoud

    2006-04-01

    We present a systematic treatment of the HS Field theory of the open bosonic string and discuss its relationship to other full string field theories of the open bosonic string such as Witten's theory and the CVS theory. In the development of the HS field theory we encounter infinite dimensional matrices arising from the change of representation between the two theories, i.e., the HS field theory and the full string field theory. We give a general procedure of how to invert these gigantic matrices. The inversion of these matrices involves the computation of many infinite sums. We give the values of these sums and state their generalizations arising from considering higher order vertices (i.e., more than three strings) in string field theory. Moreover, we give a general procedure, on how to evaluate the generalized sums, that can be extended to many generic sums of similar properties. We also discuss the conformal operator connecting the HS field theory to that of the CVS string field theory.

  16. Investigation of Wave Transmission from a Floating Wave Dragon Wave Energy Converter

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen Harck; Andersen, Thomas Lykke

    2012-01-01

    This paper focuses on the calibration of the MIKE21BW model against the measured wave height reduction behind a 24 kW/m Wave Dragon (WD) wave energy converter. A numerical model is used to determine the wave transmission through the floating WD in varying wave conditions. The transmission obtained...

  17. The Interaction between the Plane Wave and the Plate with Limited Height in Soil

    Directory of Open Access Journals (Sweden)

    N.A. Lokteva

    2017-03-01

    Full Text Available A solution of the two-dimensional task on interaction between the harmonic wave and the plate with the limited height in soil has been provided. The plate surrounded on both sides with the half-spaces filled with soil medium has been used as a vibro-absorbing obstacle. The mechanical behavior of the plate has been described by S.P. Timoshenko's shift model and the mechanical behavior of soil by a linear elasticity theory equation. The main purpose of the paper is to determine the total acceleration vector field inducted by the penetrated and radiated waves in the second half-space. The mathematical formulation of the task includes a model of upcoming wave, soil medium and plate movement equation, infinity conditions, and conditions of soil contact with obstacle. Conditions of free slip have been taken as the contact conditions between the soil and the obstacle. We have considered a closed system of equations, which includes wave equations for scalar and vector potentials, elasticity theory equations for soil mediums, Koshi's relations, physical law, and plate movement equation. The boundary conditions for the plate correspond to a hinged support. To solve this task, all functions have been expanded in trigonometric series that allowed to obtain potential values in the coefficients of the series. To define the integrations constants, the contact conditions between the obstacle and soil have been used. On the basis of the revealed potentials, we have defined displacements on the boundary between the plate and soil and in other points of the second half-space. The vibro-absorbing properties of the plate have been investigated depending on the frequency of the harmonic wave falling on the plate. From the practical point of view, this task is related to protection of buildings from vibrations formed at a distance from underground railways.

  18. Effects of N on plant response to heat-wave: a field study with prairie vegetation.

    Science.gov (United States)

    Wang, Dan; Heckathorn, Scott A; Mainali, Kumar; Hamilton, E William

    2008-11-01

    More intense, more frequent, and longer heat-waves are expected in the future due to global warming, which could have dramatic ecological impacts. Increasing nitrogen (N) availability and its dynamics will likely impact plant responses to heat stress and carbon (C) sequestration in terrestrial ecosystems. This field study examined the effects of N availability on plant response to heat-stress (HS) treatment in naturally-occurring vegetation. HS (5 d at ambient or 40.5 degrees C) and N treatments (+/-N) were applied to 16 1 m(2) plots in restored prairie vegetation dominated by Andropogon gerardii (warm-season C4 grass) and Solidago canadensis (warm-season C3 forb). Before, during, and after HS, air, canopy, and soil temperature were monitored; net CO2 assimilation (P(n)), quantum yield of photosystem II (Phi(PSII)), stomatal conductance (g(s)), and leaf water potential (Psi(w)) of the dominant species and soil respiration (R(soil)) of each plot were measured daily during HS. One week after HS, plots were harvested, and C% and N% were determined for rhizosphere and bulk soil, and above-ground tissue (green/senescent leaf, stem, and flower). Photosynthetic N-use efficiency (PNUE) and N resorption rate (NRR) were calculated. HS decreased P(n), g(s), Psi(w), and PNUE for both species, and +N treatment generally increased these variables (+/-HS), but often slowed their post-HS recovery. Aboveground biomass tended to decrease with HS in both species (and for green leaf mass in S. canadensis), but decrease with +N for A. gerardii and increase with +N for S. canadensis. For A. gerardii, HS tended to decrease N% in green tissues with +N, whereas in S. canadensis, HS increased N% in green leaves. Added N decreased NRR for A. gerardii and HS increased NRR for S. canadensis. These results suggest that heat waves, though transient, could have significant effects on plants, communities, and ecosystem N cycling, and N can influence the effect of heat waves.

  19. Ordered to isotropic morphology transition in pattern-directed dewetting of polymer thin films on substrates with different feature heights.

    Science.gov (United States)

    Roy, Sudeshna; Mukherjee, Rabibrata

    2012-10-24

    Controlled dewetting of a thin polymer film on a topographically patterned substrate is an interesting approach for aligning isotropic dewetted structures. In this article, we investigate the influence of substrate feature height (H(S)) on the dewetting pathway and final pattern morphology by studying the dewetting of polystyrene (PS) thin films on grating substrates with identical periodicity (λ(P) = 1.5 μm), but H(S) varying between 10 nm and 120 nm. We identify four distinct categories of final dewetted morphology, with different extent of ordering: (1) array of aligned droplets (H(S) ≈ 120 nm); (2) aligned undulating ribbons (H(S) ≈ 70-100 nm); (3) multilength scale structures with coexisting large droplets uncorrelated to the substrate and smaller droplets/ribbons aligned along the stripes (H(S) ≈ 40-60 nm); and (4) large droplets completely uncorrelated to the substrate (H(S) dewetted morphologies and transition across categories remain generically unaltered. We finally show that the structures obtained by dewetting on different H(S) substrates exhibits different levels of hydrophobicity because of combined spatial variation of chemical and topographic contrast along the surface. Thus, the work reported in this article can find potential application in fabricating surfaces with controlled wettability.

  20. SN 2011hs

    DEFF Research Database (Denmark)

    Bufano, F.; Pignata, G.; Bersten, M.

    2014-01-01

    Observations spanning a large wavelength range, from X-ray to radio, of the Type IIb supernova 2011hs are presented, covering its evolution during the first year after explosion. The optical light curve presents a narrower shape and a fainter luminosity at peak than previously observed for Type I...

  1. Geosat altimeter derived sea surface wind speeds and significant wave heights for the north Indian Ocean and their comparison with in situ data

    Digital Repository Service at National Institute of Oceanography (India)

    Vethamony, P.; Vaithiyanathan, R.; Almeida, A.M.; Santanam, K.; Rao, L.V.G.; Sarkar, A.; Kumar, R.; Gairola, R.M.; Gohil, B.S.

    Geosat altimeter data for the period November 1986-October 1987 over the north Indian Ocean have been processed to retrieve wind speeds and significant wave heights. Smoothed Brown algorithm is used to retrieve wind speeds from back...

  2. Long-term decline of the canopy-forming algae Gelidium corneum, associated to extreme wave events and reduced sunlight hours, in the southeastern Bay of Biscay

    Science.gov (United States)

    Borja, Angel; Chust, Guillem; Fontán, Almudena; Garmendia, Joxe Mikel; Uyarra, María C.

    2018-05-01

    Canopy-forming macroalgae are experiencing large biogeographical shifts due to climate change. One of them (Gelidium corneum) has shown a dramatic decline in biomass in northern Spain, in the past 20 years. We investigate here two most plausible hypotheses to explain its decline: (i) a combination of increasing wave energy and decrease of irradiance in the growth season; and (ii) a combination of increasing light in summer and decreasing nutrient concentration. Using a dataset of biomass and environmental variables (1993-2016), in three sectors and three water depths, we have determined that the variables explaining more biomass variability were: suspended solids, nitrate, sunlight hours, significant wave height threshold exceedances (Hs5m), temperature, silicate, and nitrite. When undertaking multiple regression analyses for the whole depth range, only the model including sunlight hours with Hs5m was selected, being highly significant (p algae from the substratum during the growth season. The decline rate in biomass with time, at each sector and depth, was highly correlated (p < 0.001) to the wave energy flux received at each depth, which was higher at 5 m in all sectors, decreasing with depth. In turn, nutrients, instead of decreasing, have increased, and only nitrate presented a significant negative correlation with G. corneum biomass, which was not significant after detrending. The significant (p = 0.001) increase in rainfall over the studied period can explain the increase of those nutrients. Hence, we question whether the effect of nutrients is such, as already described. The most likely factor explaining the decline of this macroalga was the combination of sunlight hours decrease and Hs5m increase.

  3. Numerical investigation of freak waves

    Science.gov (United States)

    Chalikov, D.

    2009-04-01

    Paper describes the results of more than 4,000 long-term (up to thousands of peak-wave periods) numerical simulations of nonlinear gravity surface waves performed for investigation of properties and estimation of statistics of extreme (‘freak') waves. The method of solution of 2-D potential wave's equations based on conformal mapping is applied to the simulation of wave behavior assigned by different initial conditions, defined by JONSWAP and Pierson-Moskowitz spectra. It is shown that nonlinear wave evolution sometimes results in appearance of very big waves. The shape of freak waves varies within a wide range: some of them are sharp-crested, others are asymmetric, with a strong forward inclination. Some of them can be very big, but not steep enough to create dangerous conditions for vessels (but not for fixed objects). Initial generation of extreme waves can occur merely as a result of group effects, but in some cases the largest wave suddenly starts to grow. The growth is followed sometimes by strong concentration of wave energy around a peak vertical. It is taking place in the course of a few peak wave periods. The process starts with an individual wave in a physical space without significant exchange of energy with surrounding waves. Sometimes, a crest-to-trough wave height can be as large as nearly three significant wave heights. On the average, only one third of all freak waves come to breaking, creating extreme conditions, however, if a wave height approaches the value of three significant wave heights, all of the freak waves break. The most surprising result was discovery that probability of non-dimensional freak waves (normalized by significant wave height) is actually independent of density of wave energy. It does not mean that statistics of extreme waves does not depend on wave energy. It just proves that normalization of wave heights by significant wave height is so effective, that statistics of non-dimensional extreme waves tends to be independent

  4. Characteristics of monsoon waves off Uran, west coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Nayak, B.U.; Chandramohan, P.; Mandal, S.

    's and the spectral methods for determining various wave parameters. Monsoon wave climate was stronger with the occurrence of the highest significant wave height of 2.45 m and the corresponding maximum wave height of 3.9 m in July. Significant wave height varied from...

  5. On the retrieval of significant wave heights from spaceborne Synthetic Aperture Radar using the Max-Planck Institut algorithm.

    Science.gov (United States)

    Violante-Carvalho, Nelson

    2005-12-01

    Synthetic Aperture Radar (SAR) onboard satellites is the only source of directional wave spectra with continuous and global coverage. Millions of SAR Wave Mode (SWM) imagettes have been acquired since the launch in the early 1990's of the first European Remote Sensing Satellite ERS-1 and its successors ERS-2 and ENVISAT, which has opened up many possibilities specially for wave data assimilation purposes. The main aim of data assimilation is to improve the forecasting introducing available observations into the modeling procedures in order to minimize the differences between model estimates and measurements. However there are limitations in the retrieval of the directional spectrum from SAR images due to nonlinearities in the mapping mechanism. The Max-Planck Institut (MPI) scheme, the first proposed and most widely used algorithm to retrieve directional wave spectra from SAR images, is employed to compare significant wave heights retrieved from ERS-1 SAR against buoy measurements and against the WAM wave model. It is shown that for periods shorter than 12 seconds the WAM model performs better than the MPI, despite the fact that the model is used as first guess to the MPI method, that is the retrieval is deteriorating the first guess. For periods longer than 12 seconds, the part of the spectrum that is directly measured by SAR, the performance of the MPI scheme is at least as good as the WAM model.

  6. Analysis of Flame Extinguishment and Height in Low Frequency Acoustically Excited Methane Jet Diffusion Flame

    Science.gov (United States)

    Zong, Ruowen; Kang, Ruxue; Liu, Chen; Zhang, Zhiyang; Zhi, Youran

    2018-01-01

    The exploration of microgravity conditions in space is increasing and existing fire extinguishing technology is often inadequate for fire safety in this special environment. As a result, improving the efficiency of portable extinguishers is of growing importance. In this work, a visual study of the effects on methane jet diffusion flames by low frequency sound waves is conducted to assess the extinguishing ability of sound waves. With a small-scale sound wave extinguishing bench, the extinguishing ability of certain frequencies of sound waves are identified, and the response of the flame height is observed and analyzed. Results show that the flame structure changes with disturbance due to low frequency sound waves of 60-100 Hz, and quenches at effective frequencies in the range of 60-90 Hz. In this range, 60 Hz is considered to be the quick extinguishing frequency, while 70-90 Hz is the stable extinguishing frequency range. For a fixed frequency, the flame height decreases with sound pressure level (SPL). The flame height exhibits the greatest sensitivity to the 60 Hz acoustic waves, and the least to the 100 Hz acoustic waves. The flame height decreases almost identically with disturbance by 70-90 Hz acoustic waves.

  7. Zonal Wave Number 2 Rossby Wave (3.5-day oscillation) Over The Martian Lower Atmosphere

    Science.gov (United States)

    Ghosh, P.; Thokuluwa, R. K.

    2013-12-01

    Over the Mars, height (800-50 Pascal pressure coordinate) profiles of temperature (K), measured by radio occultation technique during the MGS (Mars Global Surveyor) mission, obtained for the period of 1-10 January 2006 at the Martian latitude of ~63N in almost all the longitudes are analyzed to study the characteristics of the 3.5-day oscillation. To avoid significant data gaps in a particular longitude sector, we selected a set of 7 Mars longitude regions with ranges of 0-30E, 35-60E, 65-95E, 190-230E, 250-280E, 290-320E, and 325-360E to study the global characteristics of the 3.5-day oscillation. The 3.5-day oscillation is not selected as a-priori but observed as a most significant oscillation during this period of 1-10 January 2006. It is observed that in the longitude of 0-30E, the 3.5-day oscillation shows statistically significant power (above the 95% confidence level white noise) from the lowest height (800 Pascal, 8 hPa) itself and up to the height of 450 Pascal level with the maximum power of ~130 K^2 at the 600 & 650 Pascal levels. It started to grow from the power of ~ 50 K^2 at the lowest height of 800 Pascal level and reached the maximum power in the height of 600-650 Pascal level and then it started to get lessened monotonously up to the height of 450 Pascal level where its power is ~ 20 K^2. Beyond this height and up to the height of 50 Pascal level, the wave amplitude is below the white noise level. As the phase of the wave is almost constant at all the height levels, it seems that the observed 3.5-day oscillation is a stationary wave with respect to the height. In the 35-60 E longitude sector, the vertical structure of the 3.5-day oscillation is similar to what observed for the 0-30 E longitude region but the power is statistically insignificant at all the heights. However in the 65-95E longitude sector, the wave grows from the lowest level (70 K^2) of 800 Pascal to its maximum power of 280 K^2 in the height of 700 Pascal level and then it started

  8. Estimates of ocean wave heights and attenuation in sea ice using the SAR wave mode on Sentinel-1A

    Science.gov (United States)

    Ardhuin, Fabrice; Collard, Fabrice; Chapron, Bertrand; Girard-Ardhuin, Fanny; Guitton, Gilles; Mouche, Alexis; Stopa, Justin E.

    2015-04-01

    Swell evolution from the open ocean into sea ice is poorly understood, in particular the amplitude attenuation expected from scattering and dissipation. New synthetic aperture radar (SAR) data from Sentinel-1A wave mode reveal intriguing patterns of bright oscillating lines shaped like instant noodles. We investigate cases in which the oscillations are in the azimuth direction, around a straight line in the range direction. This observation is interpreted as the distortion by the SAR processing of crests from a first swell, due to the presence of a second swell. Since deviations from a straight line should be proportional to the orbital velocity toward the satellite, swell height can be estimated, from 1.5 to 5 m in the present case. The evolution of this 13 s period swell across the ice pack is consistent with an exponential attenuation on a length scale of 200 km.

  9. Trends in significant wave height and surface wind speed in the China Seas between 1988 and 2011

    Science.gov (United States)

    Zheng, Chongwei; Zhang, Ren; Shi, Weilai; Li, Xin; Chen, Xuan

    2017-10-01

    Wind and waves are key components of the climate system as they drive air-sea interactions and influence weather systems and atmospheric circulation. In marine environments, understanding surface wind and wave fields and their evolution over time is important for conducting safe and efficient human activities, such as navigation and engineering. This study considers long-term trends in the sea surface wind speed (WS) and significant wave height (SWH) in the China Seas over the period 1988-2011 using the Cross-Calibrated Multi-Platform (CCMP) ocean surface wind product and a 24-year hindcast wave dataset obtained from the WAVEWATCH-III (WW3) wave model forced with CCMP winds. The long-term trends in WS and SWH in the China Seas are analyzed over the past 24 years to provide a reference point from which to assess future climate change and offshore wind and wave energy resource development in the region. Results demonstrate that over the period 1988-2011 in the China Seas: 1) WS and SWH showed a significant increasing trend of 3.38 cm s-1 yr-1 and 1.52 cm yr-1, respectively; 2) there were notable regional differences in the long-term trends of WS and SWH; 3) areas with strong increasing trends were located mainly in the middle of the Tsushima Strait, the northern and southern areas of the Taiwan Strait, and in nearshore regions of the northern South China Sea; and 4) the long-term trend in WS was closely associated with El Niño and a significant increase in the occurrence of gale force winds in the region.

  10. Wave attenuation charcteristics of tethered float system

    Digital Repository Service at National Institute of Oceanography (India)

    Vethamony, P.

    incident wave height transmitted wave height G wave number float mass number of rows of floats drag power transmitted wave power incident wave power 111 112 P. Vethamony float radius wave period time velocity and acceleration of fluid... particles, respectively wave attenuation in percentage displacement, velocity and acceleration of float, respectively amplitude of float displacement added mass damping coefficient fluid particle displacement amplitude of fluid particle displacement...

  11. Statistical analysis on extreme wave height

    Digital Repository Service at National Institute of Oceanography (India)

    Teena, N.V.; SanilKumar, V.; Sudheesh, K.; Sajeev, R.

    -294. • WAFO (2000) – A MATLAB toolbox for analysis of random waves and loads, Lund University, Sweden, homepage http://www.maths.lth.se/matstat/wafo/,2000. 15    Table 1: Statistical results of data and fitted distribution for cumulative distribution...

  12. CFD study of the overtopping discharge of the Wave Dragon wave energy converter

    DEFF Research Database (Denmark)

    Eskilsson, K.; Palm, J.; Kofoed, Jens Peter

    2015-01-01

    incompressible Euler/Navier-Stokes solver in the OpenFOAM® framework. We present simulations of: (i) a complete sea state for different crest heights, and (ii) regular waves for different wave conditions and crest heights. The simulations compare reasonably well with the experimental data, albeit the irregular...

  13. [hsCRP protein in children and adolescents with diabetes type 1].

    Science.gov (United States)

    Głowińska-Olszewska, Barbara; Urban, Mirosława; Peczyńska, Jadwiga; Koput, Alicja

    2007-01-01

    HsCRP protein is known as a novel marker of low grade inflammatory state, which characterises an atherosclerotic process in its early stages. Contrary to a large amount of data on inflammatory markers in diabetes type 2 and metabolic syndrome in adults, little is known so far about the inflammatory process in diabetes type 1, especially in children. The aim of the study was to estimate the level of hsCRP protein in children and adolescents with diabetes type 1 depending on coexisting additional risk factors for atherosclerosis and microvascular complications. 127 children and adolescents with diabetes duration 6.7+/-3.3 years, aged 14.9+/-3.1, were studied. The control group consisted of 52 healthy children aged 14.9+/-2.8 years, matched acc. to gender. HsCRP level was assessed with use of immunoturbidymetric, latex augmented method (Tina-quant CRP (Latex) HS, Roche). HsCRP in the whole study group was nearly significantly higher compared to control group: 0.17+/-0.2 vs. 0.078+/-0.1 mg/dl, p=0.072. In diabetic hypertensive children (n=38) we found significantly higher levels of hsCRP compared to controls (0.27+/-0.3 vs. 0.07 mg/dl, p=0.008) and compared to diabetic normotensive children (0.13+/-0.22 mg/dl; p=0.024). Diabetic obese patients (n=23) had significantly higer hsCRP compared to controls (0.24+/-0.3 vs. 0.07+/-0.1 mg/dl, p=0.04). In 14 studied diabetic children we found coexisting hypertension and obesity, and we found further increase in hsCRP level - 0.28+/-0.3 mg/dl. In diabetic children with microangiopathy hsCRP level was 0.22+/-0.2 mg/dl, and it was insignificantly higher compared to controls and to diabetic children without complications. Correlation analysis showed interrelations between hsCRP and systolic blood pressure (r=0.2; p=0.04) and HbA1c (r=0.25; p=0.015). In stepwise regression analysis hsCRP was related to systolic blood pressure, HbA1c and the triglycerides level (R=0.37; p=0.003). In children and adolescents with diabetes type 1 we

  14. Waves in the seas

    Digital Repository Service at National Institute of Oceanography (India)

    Varkey, M.J

    , steep nonsymmetric cnoidal waves, solitons and random waves. They have different properties too. Any wave form has a wave period (T), wave height (H) and speed (C) which depends on T. Still another type of waves are breaking waves near a coast...

  15. Statistical Analysis of Wave Climate Data Using Mixed Distributions and Extreme Wave Prediction

    Directory of Open Access Journals (Sweden)

    Wei Li

    2016-05-01

    Full Text Available The investigation of various aspects of the wave climate at a wave energy test site is essential for the development of reliable and efficient wave energy conversion technology. This paper presents studies of the wave climate based on nine years of wave observations from the 2005–2013 period measured with a wave measurement buoy at the Lysekil wave energy test site located off the west coast of Sweden. A detailed analysis of the wave statistics is investigated to reveal the characteristics of the wave climate at this specific test site. The long-term extreme waves are estimated from applying the Peak over Threshold (POT method on the measured wave data. The significant wave height and the maximum wave height at the test site for different return periods are also compared. In this study, a new approach using a mixed-distribution model is proposed to describe the long-term behavior of the significant wave height and it shows an impressive goodness of fit to wave data from the test site. The mixed-distribution model is also applied to measured wave data from four other sites and it provides an illustration of the general applicability of the proposed model. The methodologies used in this paper can be applied to general wave climate analysis of wave energy test sites to estimate extreme waves for the survivability assessment of wave energy converters and characterize the long wave climate to forecast the wave energy resource of the test sites and the energy production of the wave energy converters.

  16. Wave-current interactions at the FloWave Ocean Energy Research Facility

    Science.gov (United States)

    Noble, Donald; Davey, Thomas; Steynor, Jeffrey; Bruce, Tom; Smith, Helen; Kaklis, Panagiotis

    2015-04-01

    Physical scale model testing is an important part of the marine renewable energy development process, allowing the study of forces and device behaviour in a controlled environment prior to deployment at sea. FloWave is a new state-of-the-art ocean energy research facility, designed to provide large scale physical modelling services to the tidal and wave sector. It has the unique ability to provide complex multi-directional waves that can be combined with currents from any direction in the 25m diameter circular tank. The facility is optimised for waves around 2s period and 0.4m height, and is capable of generating currents upwards of 1.6m/s. This offers the ability to model metocean conditions suitable for most renewable energy devices at a typical scale of between 1:10 and 1:40. The test section is 2m deep, which can be classed as intermediate-depth for most waves of interest, thus the full dispersion equation must be solved as the asymptotic simplifications do not apply. The interaction between waves and currents has been studied in the tank. This has involved producing in the tank sets of regular waves, focussed wave groups, and random sea spectra including multi-directional sea states. These waves have been both inline-with and opposing the current, as well as investigating waves at arbitrary angles to the current. Changes in wave height and wavelength have been measured, and compared with theoretical results. Using theoretical wave-current interaction models, methods have been explored to "correct" the wave height in the central test area of the tank when combined with a steady current. This allows the wave height with current to be set equal to that without a current. Thus permitting, for example, direct comparison of device motion response between tests with and without current. Alternatively, this would also permit a specific wave height and current combination to be produced in the tank, reproducing recorded conditions at a particular site of interest. The

  17. Generation and Limiters of Rogue Waves

    Science.gov (United States)

    2014-06-01

    Jacobs, 7320 Ruth H. Preller, 7300 1231 1008.3 E. R. Franchi , 7000 Erick Rogers, 7322 1. REFERENCES AND ENCLOSURES 2. TYPE OF PUBLICATION OR...wave heights do not grow unlimited. With massive amount of global wave observations available nowadays, wave heights much in excess of 30m have never

  18. Projecting of wave height and water level on reef-lined coasts due to intensified tropical cyclones and sea level rise in Palau to 2100

    Science.gov (United States)

    Hongo, Chuki; Kurihara, Haruko; Golbuu, Yimnang

    2018-03-01

    Tropical cyclones (TCs) and sea level rise (SLR) cause major problems including beach erosion, saltwater intrusion into groundwater, and damage to infrastructure in coastal areas. The magnitude and extent of damage is predicted to increase as a consequence of future climate change and local factors. Upward reef growth has attracted attention for its role as a natural breakwater, reducing the risks of natural disasters to coastal communities. However, projections of change in the risk to coastal reefs under conditions of intensified TCs and SLR are poorly quantified. In this study we projected the wave height and water level on Melekeok reef in the Palau Islands by 2100, based on wave simulations under intensified TCs (significant wave height at the outer ocean: SWHo = 8.7-11.0 m; significant wave period at the outer ocean: SWPo = 13-15 s) and SLR (0.24-0.98 m). To understand effects of upward reef growth on the reduction of the wave height and water level, the simulation was conducted for two reef condition scenarios: a degraded reef and a healthy reef. Moreover, analyses of reef growth based on a drilled core provided an assessment of the coral community and rate of reef production necessary to reduce the risk from TCs and SLR on the coastal areas. According to our calculations under intensified TCs and SLR by 2100, significant wave heights at the reef flat (SWHr) will increase from 1.05-1.24 m at present to 2.14 m if reefs are degraded. Similarly, by 2100 the water level at the shoreline (WLs) will increase from 0.86-2.10 m at present to 1.19-3.45 m if reefs are degraded. These predicted changes will probably cause beach erosion, saltwater intrusion into groundwater, and damage to infrastructure, because the coastal village is located at ˜ 3 m above the present mean sea level. These findings imply that even if the SWHr is decreased by only 0.1 m by upward reef growth, it will probably reduce the risks of costal damages. Our results showed that a healthy reef

  19. SU(2 Yang–Mills Theory: Waves, Particles, and Quantum Thermodynamics

    Directory of Open Access Journals (Sweden)

    Ralf Hofmann

    2016-08-01

    Full Text Available We elucidate how Quantum Thermodynamics at temperature T emerges from pure and classical S U ( 2 Yang–Mills theory on a four-dimensional Euclidean spacetime slice S 1 × R 3 . The concept of a (deconfining thermal ground state, composed of certain solutions to the fundamental, classical Yang–Mills equation, allows for a unified addressation of both (classical wave- and (quantum particle-like excitations thereof. More definitely, the thermal ground state represents the interplay between nonpropagating, periodic configurations which are electric-magnetically (antiselfdual in a non-trivial way and possess topological charge modulus unity. Their trivial-holonomy versions—Harrington–Shepard (HS (anticalorons—yield an accurate a priori estimate of the thermal ground state in terms of spatially coarse-grained centers, each containing one quantum of action ℏ localized at its inmost spacetime point, which induce an inert adjoint scalar field ϕ ( | ϕ | spatio-temporally constant. The field ϕ , in turn, implies an effective pure-gauge configuration, a μ gs , accurately describing HS (anticaloron overlap. Spatial homogeneity of the thermal ground-state estimate ϕ , a μ gs demands that (anticaloron centers are densely packed, thus representing a collective departure from (antiselfduality. Effectively, such a “nervous” microscopic situation gives rise to two static phenomena: finite ground-state energy density ρ gs and pressure P gs with ρ gs = − P gs as well as the (adjoint Higgs mechanism. The peripheries of HS (anticalorons are static and resemble (antiselfdual dipole fields whose apparent dipole moments are determined by | ϕ | and T, protecting them against deformation potentially caused by overlap. Such a protection extends to the spatial density of HS (anticaloron centers. Thus the vacuum electric permittivity ϵ 0 and magnetic permeability μ 0 , supporting the propagation of wave-like disturbances in the U ( 1 Cartan

  20. Ocean wave characteristic in the Sunda Strait using Wave Spectrum Model

    Science.gov (United States)

    Rachmayani, R.; Ningsih, N. S.; Adiprabowo, S. R.; Nurfitri, S.

    2018-03-01

    The wave characteristics including significant wave height and direction, seas and swell in the Sunda Strait are analyzed seasonally to provide marine weather information. This is crucial for establishing secured marine activities between islands of Sumatera and Java. Ocean wave characteristics in the Sunda Strait are simulated for one year (July 1996–June 1977) by using SWAN numerical model. The ocean wave characteristics in the Sunda Strait are divided into three areas of interest; southern, centre and northern part of the Sunda Strait. Despite a weaker local wind, the maximum significant wave height is captured at the southern part with its height of 2.6 m in November compared to other seasonally months. This is associated with the dominated swell from the Indian Ocean contributes on wave energy toward the Sunda Strait. The 2D spectrum analysis exhibits the monthly wave characteristic at southern part that is dominated by seas along the year and swell propagating from the Indian Ocean to the Sunda Strait during December to February (northwest monsoon), May, and November. Seas and swell at northern part of the Sunda Strait are apprehended weaker compared to other parts of the Sunda Strait due to its location is farther from the Indian Ocean.

  1. Intralesional triamcinolone for flares of hidradenitis suppurativa (HS)

    DEFF Research Database (Denmark)

    Riis, Peter Theut; Boer, Jurr; Prens, Errol P

    2016-01-01

    (triamcinolone acetonide 10 mg/mL) in the management of acute flares in HS. METHODS: This was a prospective case series evaluating the effect of intralesional corticosteroids for alleviation of acute flares in HS. Physician- and patient-reported outcomes were noted. RESULTS: Significant reductions in physician......-assessed erythema (median score from 2-1, P edema (median score from 2-1, P

  2. HS06 Benchmark for an ARM Server

    Science.gov (United States)

    Kluth, Stefan

    2014-06-01

    We benchmarked an ARM cortex-A9 based server system with a four-core CPU running at 1.1 GHz. The system used Ubuntu 12.04 as operating system and the HEPSPEC 2006 (HS06) benchmarking suite was compiled natively with gcc-4.4 on the system. The benchmark was run for various settings of the relevant gcc compiler options. We did not find significant influence from the compiler options on the benchmark result. The final HS06 benchmark result is 10.4.

  3. HS06 benchmark for an ARM server

    International Nuclear Information System (INIS)

    Kluth, Stefan

    2014-01-01

    We benchmarked an ARM cortex-A9 based server system with a four-core CPU running at 1.1 GHz. The system used Ubuntu 12.04 as operating system and the HEPSPEC 2006 (HS06) benchmarking suite was compiled natively with gcc-4.4 on the system. The benchmark was run for various settings of the relevant gcc compiler options. We did not find significant influence from the compiler options on the benchmark result. The final HS06 benchmark result is 10.4.

  4. Band gaps and localization of surface water waves over large-scale sand waves with random fluctuations

    Science.gov (United States)

    Zhang, Yu; Li, Yan; Shao, Hao; Zhong, Yaozhao; Zhang, Sai; Zhao, Zongxi

    2012-06-01

    Band structure and wave localization are investigated for sea surface water waves over large-scale sand wave topography. Sand wave height, sand wave width, water depth, and water width between adjacent sand waves have significant impact on band gaps. Random fluctuations of sand wave height, sand wave width, and water depth induce water wave localization. However, random water width produces a perfect transmission tunnel of water waves at a certain frequency so that localization does not occur no matter how large a disorder level is applied. Together with theoretical results, the field experimental observations in the Taiwan Bank suggest band gap and wave localization as the physical mechanism of sea surface water wave propagating over natural large-scale sand waves.

  5. Analysis of the optical emission of the young precataclysmic variables HS 1857+5144 and ABELL 65

    Science.gov (United States)

    Shimansky, V. V.; Pozdnyakova, S. A.; Borisov, N. V.; Bikmaev, I. F.; Vlasyuk, V. V.; Spiridonova, O. I.; Galeev, A. I.; Mel'Nikov, S. S.

    2009-10-01

    We analyze the physical state and the properties of the close binary systems HS 1857+5144 and Abell 65. We took the spectra of both systems over a wide range of orbital phases with the 6-m telescope of the Special Astrophysical Observatory of the Russian Academy of Sciences (SAO RAS) and obtained their multicolor light curves with the RTT150 and Zeiss-1000 telescopes of the SAO RAS. We demonstrate that both Abell 65 and HS 1857+5144 are young precataclysmic variables (PV) with orbital periods of P orb = 1. d 003729 and P orb = 0. d 26633331, respectively. The observed brightness and spectral variations during the orbital period are due to the radiation of the cold component, which absorbs the short-wave radiation of the hot component and reemits it in the visual part of the spectrum. A joint analysis of the brightness and radial velocity curves allowed us to find the possible and optimum sets of their fundamental parameters. We found the luminosity excesses of the secondary components of HS 1857+5144 and Abell 65 with respect to the corresponding Main Sequence stars to be typical for such objects. The excess luminosities of the secondary components of all young PVs are indicative of their faster relaxation rate towards the quiescent state compared to the rates estimated in earlier studies.

  6. Investigation of the relationship between hurricane waves and extreme runup

    Science.gov (United States)

    Thompson, D. M.; Stockdon, H. F.

    2006-12-01

    In addition to storm surge, the elevation of wave-induced runup plays a significant role in forcing geomorphic change during extreme storms. Empirical formulations for extreme runup, defined as the 2% exceedence level, are dependent on some measure of significant offshore wave height. Accurate prediction of extreme runup, particularly during hurricanes when wave heights are large, depends on selecting the most appropriate measure of wave height that provides energy to the nearshore system. Using measurements from deep-water wave buoys results in an overprediction of runup elevation. Under storm forcing these large waves dissipate across the shelf through friction, whitecapping and depth-limited breaking before reaching the beach and forcing swash processes. The use of a local, shallow water wave height has been shown to provide a more accurate estimate of extreme runup elevation (Stockdon, et. al. 2006); however, a specific definition of this local wave height has yet to be defined. Using observations of nearshore waves from the U.S. Army Corps of Engineers' Field Research Facility (FRF) in Duck, NC during Hurricane Isabel, the most relevant measure of wave height for use in empirical runup parameterizations was examined. Spatial and temporal variability of the hurricane wave field, which made landfall on September 18, 2003, were modeled using SWAN. Comparisons with wave data from FRF gages and deep-water buoys operated by NOAA's National Data Buoy Center were used for model calibration. Various measures of local wave height (breaking, dissipation-based, etc.) were extracted from the model domain and used as input to the runup parameterizations. Video based observations of runup collected at the FRF during the storm were used to ground truth modeled values. Assessment of the most appropriate measure of wave height can be extended over a large area through comparisons to observations of storm- induced geomorphic change.

  7. An Evaluation of the Performance Diagnostic Checklist-Human Services (PDC-HS) Across Domains.

    Science.gov (United States)

    Wilder, David A; Lipschultz, Joshua; Gehrman, Chana

    2018-06-01

    The Performance Diagnostic Checklist-Human Services (PDC-HS) is an informant-based tool designed to assess the environmental variables that contribute to poor employee performance in human service settings. Although the PDC-HS has been shown to effectively identify variables contributing to problematic performance, interventions based on only two of the four PDC-HS domains have been evaluated to date. In addition, the extent to which PDC-HS-indicated interventions are more effective than nonindicated interventions for two domains remains unclear. In the current study, we administered the PDC-HS to supervisors to assess the variables contributing to infrequent teaching of verbal operants and use of a timer by therapists at a center-based autism treatment program. Each of the four PDC-HS domains was identified as contributing to poor performance for at least one therapist. We then evaluated PDC-HS-indicated interventions for each domain. In addition, to assess the predictive validity of the tool, we evaluated various nonindicated interventions prior to implementing a PDC-HS-indicated intervention for two of the four domains. Results suggest that the PDC-HS-indicated interventions were effective across all four domains and were more effective than the nonindicated interventions for the two domains for which they were evaluated. Results are discussed in terms of the utility of the PDC-HS to identify appropriate interventions to manage therapist performance in human service settings.

  8. Mixing height determination from the momentum balance of the neutral or stable PBL

    Energy Technology Data Exchange (ETDEWEB)

    Bergmann, J.C. [Risoe National Lab., Roskilde (Denmark)

    1997-10-01

    The mixing height is defined by the top of the layer of turbulent mixing. This height is equal to the height H of turbulent vertical momentum transport (fiction) in neutral or stable stratification. In very stable cases, the wave induced momentum transport must be excluded if the waves do not have mixing effects (e.g. break) within the frictional layer. Thus the conditions provided by the momentum balance determine the mixing height in most cases of mechanical turbulence. Mixing is a time dependent process and depends also on the height of release of substance to be mixed. It depends on the specific form of the exchange coefficient function whether the mixing time for the mixed layer is finite of infinite. If this time is infinite, an additional mixing time criterion for a substance released close to the ground must be applied for the determination of the corresponding mixing height. (au)

  9. Role of grounded ship 'MV River Princess' in triggering erosion: A case study from Candolim Sinquerim Coast, Goa.

    Digital Repository Service at National Institute of Oceanography (India)

    ManiMurali, R.; Babu, M.T.; Sudhesh, K.; Mascarenhas, A.; Vethamony, P.

    are conducive for sand bar formation on the lee side. The intensity of winds and higher significant wave height (Hs) during SW monsoon further deteriorates the shore front which has already become fragile due to severe erosion along beach front...

  10. Characteristics of offshore extreme wind-waves detected by surface drifters with a low-cost GPS wave sensor

    Science.gov (United States)

    Komatsu, Kosei

    Wind-generated waves have been recognized as one of the most important factors of the sea surface roughness which plays crucial roles in various air-sea interactions such as energy, mo-mentum, heat and gas exchanges. At the same time, wind waves with extreme wave heights representatively called as freak or rogue waves have been a matter of great concern for many people involved in shipping, fishing, constracting, surfing and other marine activities, because such extreme waves frequently affect on the marine activities and sometimes cause serious dis-asters. Nevertheless, investigations of actual conditions for the evolution of wind waves in the offshore region are less and sparse in contrast to dense monitoring networks in the coastal re-gions because of difficulty of offshore observation with high accuracy. Recently accurate in situ observation of offshore wind waves is getting possible at low cost owing to a wave height and di-rection sensor developed by Harigae et al. (2004) by installing a point-positioning GPS receiver on a surface drifting buoy. The point-positioning GPS sensor can extract three dimensional movements of the buoy excited by ocean waves with minimizing effects of GPS point-positioning errors through the use of a high-pass filter. Two drifting buoys equipped with the GPS-based wave sensor charged by solar cells were drifted in the western North Pacific and one of them continued to observe wind waves during 16 months from Sep. 2007. The RMSE of the GPS-based wave sensor was less than 10cm in significant wave height and about 1s in significant wave period in comparison with other sensors, i.e. accelerometers installed on drifting buoys of Japan Meteorological Agency, ultrasonic sensors placed at the Hiratsuka observation station of the University of Tokyo and altimeter of the JASON-1. The GPS-based wave buoys enabled us to detect freak waves defined as waves whose height is more than twice the significant wave height. The observation conducted by

  11. Projecting of wave height and water level on reef-lined coasts due to intensified tropical cyclones and sea level rise in Palau to 2100

    Directory of Open Access Journals (Sweden)

    C. Hongo

    2018-03-01

    Full Text Available Tropical cyclones (TCs and sea level rise (SLR cause major problems including beach erosion, saltwater intrusion into groundwater, and damage to infrastructure in coastal areas. The magnitude and extent of damage is predicted to increase as a consequence of future climate change and local factors. Upward reef growth has attracted attention for its role as a natural breakwater, reducing the risks of natural disasters to coastal communities. However, projections of change in the risk to coastal reefs under conditions of intensified TCs and SLR are poorly quantified. In this study we projected the wave height and water level on Melekeok reef in the Palau Islands by 2100, based on wave simulations under intensified TCs (significant wave height at the outer ocean: SWHo = 8.7–11.0 m; significant wave period at the outer ocean: SWPo = 13–15 s and SLR (0.24–0.98 m. To understand effects of upward reef growth on the reduction of the wave height and water level, the simulation was conducted for two reef condition scenarios: a degraded reef and a healthy reef. Moreover, analyses of reef growth based on a drilled core provided an assessment of the coral community and rate of reef production necessary to reduce the risk from TCs and SLR on the coastal areas. According to our calculations under intensified TCs and SLR by 2100, significant wave heights at the reef flat (SWHr will increase from 1.05–1.24 m at present to 2.14 m if reefs are degraded. Similarly, by 2100 the water level at the shoreline (WLs will increase from 0.86–2.10 m at present to 1.19–3.45 m if reefs are degraded. These predicted changes will probably cause beach erosion, saltwater intrusion into groundwater, and damage to infrastructure, because the coastal village is located at  ∼ 3 m above the present mean sea level. These findings imply that even if the SWHr is decreased by only 0.1 m by upward reef growth, it will probably reduce the risks of

  12. Relationship of HS CRP and Sacroiliac Joint Inflammation in Undifferentiated Spondyloarthritis.

    Science.gov (United States)

    Liu, Te-Jung; Chang, Cheng-Chiang; Chen, Liang-Cheng; Chu, Heng-Yi; Hsu, Chun-Sheng; Chang, Shin-Tsu

    2018-01-01

    Elevation of serum high sensitivity C-reactive protein (hs-CRP) level has been demonstrated as a risk factor for varying diseases, as well as a biomarker for predicting recovery after operation of lumber disc herniation. Our objective was to investigate the relationship between serum hs-CRP and sacroiliac (SI) joint inflammation in patients with undifferentiated spondyloarthritis (uSpA). In this retrospective study, we enrolled patients with uSpA who underwent hs-CRP testing between January 2007 and September 2013. Serum hs-CRP was analyzed at our central laboratory. All enrolled patients underwent skeletal scintigraphic scan with quantitative sacroiliac measurement. A total of 29 patients were enrolled with mean age 32.27 years and female:male ratio of 6:23. Pearson's correlation coefficient showed a significant difference between hs-CRP in serum and SI/S ratio in uSpA, particularly the middle part of the sacroiliac joint, either right side or left side. The significantly high concentration of serum hs-CRP might indicate a systemic inflammatory response to flare-up of the SI joint and might be an indicator of SI inflammation in uSpA.

  13. Relationship of HS CRP and Sacroiliac Joint Inflammation in Undifferentiated Spondyloarthritis

    Science.gov (United States)

    Liu, Te-Jung; Chang, Cheng-Chiang; Chen, Liang-Cheng; Chu, Heng-Yi; Hsu, Chun-Sheng; Chang, Shin-Tsu

    2018-01-01

    Abstract Objective Elevation of serum high sensitivity C-reactive protein (hs-CRP) level has been demonstrated as a risk factor for varying diseases, as well as a biomarker for predicting recovery after operation of lumber disc herniation. Our objective was to investigate the relationship between serum hs-CRP and sacroiliac (SI) joint inflammation in patients with undifferentiated spondyloarthritis (uSpA). Methods In this retrospective study, we enrolled patients with uSpA who underwent hs-CRP testing between January 2007 and September 2013. Serum hs-CRP was analyzed at our central laboratory. All enrolled patients underwent skeletal scintigraphic scan with quantitative sacroiliac measurement. Results A total of 29 patients were enrolled with mean age 32.27 years and female:male ratio of 6:23. Pearson’s correlation coefficient showed a significant difference between hs-CRP in serum and SI/S ratio in uSpA, particularly the middle part of the sacroiliac joint, either right side or left side. The significantly high concentration of serum hs-CRP might indicate a systemic inflammatory response to flare-up of the SI joint and might be an indicator of SI inflammation in uSpA. PMID:29785410

  14. Wave run-up on sandbag slopes

    Directory of Open Access Journals (Sweden)

    Thamnoon Rasmeemasmuang

    2014-03-01

    Full Text Available On occasions, sandbag revetments are temporarily applied to armour sandy beaches from erosion. Nevertheless, an empirical formula to determine the wave run -up height on sandbag slopes has not been available heretofore. In this study a wave run-up formula which considers the roughness of slope surfaces is proposed for the case of sandbag slopes. A series of laboratory experiments on the wave run -up on smooth slopes and sandbag slopes were conducted in a regular-wave flume, leading to the finding of empirical parameters for the formula. The proposed empirical formula is applicable to wave steepness ranging from 0.01 to 0.14 and to the thickness of placed sandbags relative to the wave height ranging from 0.17 to 3.0. The study shows that the wave run-up height computed by the formula for the sandbag slopes is 26-40% lower than that computed by the formula for the smooth slopes.

  15. Modelling Of Anticipated Damage Ratio On Breakwaters Using Fuzzy Logic

    Science.gov (United States)

    Mercan, D. E.; Yagci, O.; Kabdasli, S.

    2003-04-01

    In breakwater design the determination of armour unit weight is especially important in terms of the structure's life. In a typical experimental breakwater stability study, different wave series composed of different wave heights; wave period and wave steepness characteristics are applied in order to investigate performance the structure. Using a classical approach, a regression equation is generated for damage ratio as a function of characteristic wave height. The parameters wave period and wave steepness are not considered. In this study, differing from the classical approach using a fuzzy logic, a relationship between damage ratio as a function of mean wave period (T_m), wave steepness (H_s/L_m) and significant wave height (H_s) was further generated. The system's inputs were mean wave period (T_m), wave steepness (H_s/L_m) and significant wave height (H_s). For fuzzification all input variables were divided into three fuzzy subsets, their membership functions were defined using method developed by Mandani (Mandani, 1974) and the rules were written. While for defuzzification the centroid method was used. In order to calibrate and test the generated models an experimental study was conducted. The experiments were performed in a wave flume (24 m long, 1.0 m wide and 1.0 m high) using 20 different irregular wave series (P-M spectrum). Throughout the study, the water depth was 0.6 m and the breakwater cross-sectional slope was 1V/2H. In the armour layer, a type of artificial armour unit known as antifer cubes were used. The results of the established fuzzy logic model and regression equation model was compared with experimental data and it was determined that the established fuzzy logic model gave a more accurate prediction of the damage ratio on this type of breakwater. References Mandani, E.H., "Application of Fuzzy Algorithms for Control of Simple Dynamic Plant", Proc. IEE, vol. 121, no. 12, December 1974.

  16. Risk analysis of breakwater caisson under wave attack using load surface approximation

    Science.gov (United States)

    Kim, Dong Hyawn

    2014-12-01

    A new load surface based approach to the reliability analysis of caisson-type breakwater is proposed. Uncertainties of the horizontal and vertical wave loads acting on breakwater are considered by using the so-called load surfaces, which can be estimated as functions of wave height, water level, and so on. Then, the first-order reliability method (FORM) can be applied to determine the probability of failure under the wave action. In this way, the reliability analysis of breakwaters with uncertainties both in wave height and in water level is possible. Moreover, the uncertainty in wave breaking can be taken into account by considering a random variable for wave height ratio which relates the significant wave height to the maximum wave height. The proposed approach is applied numerically to the reliability analysis of caisson breakwater under wave attack that may undergo partial or full wave breaking.

  17. Scenario based tsunami wave height estimation towards hazard evaluation for the Hellenic coastline and examples of extreme inundation zones in South Aegean

    Science.gov (United States)

    Melis, Nikolaos S.; Barberopoulou, Aggeliki; Frentzos, Elias; Krassanakis, Vassilios

    2016-04-01

    A scenario based methodology for tsunami hazard assessment is used, by incorporating earthquake sources with the potential to produce extreme tsunamis (measured through their capacity to cause maximum wave height and inundation extent). In the present study we follow a two phase approach. In the first phase, existing earthquake hazard zoning in the greater Aegean region is used to derive representative maximum expected earthquake magnitude events, with realistic seismotectonic source characteristics, and of greatest tsunamigenic potential within each zone. By stacking the scenario produced maximum wave heights a global maximum map is constructed for the entire Hellenic coastline, corresponding to all expected extreme offshore earthquake sources. Further evaluation of the produced coastline categories based on the maximum expected wave heights emphasizes the tsunami hazard in selected coastal zones with important functions (i.e. touristic crowded zones, industrial zones, airports, power plants etc). Owing to its proximity to the Hellenic Arc, many urban centres and being a popular tourist destination, Crete Island and the South Aegean region are given a top priority to define extreme inundation zoning. In the second phase, a set of four large coastal cities (Kalamata, Chania, Heraklion and Rethymno), important for tsunami hazard, due i.e. to the crowded beaches during the summer season or industrial facilities, are explored towards preparedness and resilience for tsunami hazard in Greece. To simulate tsunamis in the Aegean region (generation, propagation and runup) the MOST - ComMIT NOAA code was used. High resolution DEMs for bathymetry and topography were joined via an interface, specifically developed for the inundation maps in this study and with similar products in mind. For the examples explored in the present study, we used 5m resolution for the topography and 30m resolution for the bathymetry, respectively. Although this study can be considered as

  18. Links of the significant wave height distribution in the Mediterranean sea with the Northern Hemisphere teleconnection patterns

    Directory of Open Access Journals (Sweden)

    P. Lionello

    2008-06-01

    Full Text Available This study analyzes the link between the SWH (Significant Wave Height distribution in the Mediterranean Sea during the second half of the 20th century and the Northern Hemisphere SLP (Sea Level Pressure teleconnection patterns.

    The SWH distribution is computed using the WAM (WAve Model forced by the surface wind fields provided by the ERA-40 reanalysis for the period 1958–2001. The time series of mid-latitude teleconnection patterns are downloaded from the NOAA web site. This study shows that several mid-latitude patterns are linked to the SWH field in the Mediterranean, especially in its western part during the cold season: East Atlantic Pattern (EA, Scandinavian Pattern (SCA, North Atlantic Oscillation (NAO, East Atlantic/West Russia Pattern (EA/WR and East Pacific/ North Pacific Pattern (EP/NP. Though the East Atlantic pattern exerts the largest influence, it is not sufficient to characterize the dominant variability. NAO, though relevant, has an effect smaller than EA and comparable to other patterns. Some link results from possibly spurious structures. Patterns which have a very different global structure are associated to similar spatial features of the wave variability in the Mediterranean Sea. These two problems are, admittedly, shortcomings of this analysis, which shows the complexity of the response of the Mediterranean SWH to global scale SLP teleconnection patterns.

  19. Wave Analysis for West Coast of South Myanmar

    Directory of Open Access Journals (Sweden)

    Xu Yanan

    2015-01-01

    Full Text Available The characteristic of southern parts of Myanmar is tropical monsoon climate, and this area is affected by few typhoons. The wave height is changed with season, the field measured data shows that the aver-age monthly maximum wave height is in June. The wave height, swelling from Indian Ocean and spreading to research area, is small. The research adopts SWAN model to simulate the waves that are transformed from off-shore to nearshore Myanmar based on the meteorological data from ECMWF. The simulated results were com-pared with satellite data and field measured data, it showed that the trend between the curves is unified, and the extreme value of simulation is close to the measured value. The simulation presents wave distribution around Myanmar southern sea, it shows that the wave height and wave directions are affected by terrain refraction and island trains shielding. When the wave is from WSW direction, the wave will be decreased fast caused by island shielding, and the direction turns to W direction at northern coastline. When the wave comes from SSW direction, the island shielding will be weak, the wave will be decreased slowly, and the direction will turn to SW direction at southern coastline.

  20. Numerical simulation of the temperature, electron density, and electric field distributions near the ionospheric reflection height after turn-on of a powerful HF wave

    International Nuclear Information System (INIS)

    Muldrew, D.B.

    1986-01-01

    The time variation of the electron temperature profile in the ionosphere following turn-on of a powerful 1-s HF pulse is determined numerically from the energy balance equation. Using this and the equations of motion and continuity for a plasma, the effect of heating and the pondermotive force of a powerful HF wave on the electron density and electric field distributions are determined by numerical simulation. The temperature variation and ponderomotive force modify the density distribution, and this new density distribution, in turn, modifies the electric field distribution of the HF wave. The density deviations grow for a few hundred milliseconds after HF turn-on and then begin to fluctuate in time. At all heights the wave number of the density deviations is approximately twice the wave number of the HF wave. For electric fields near reflection of about 6.0 V/m, the electric field distribution becomes complicated, apparently depending on Bragg scattering of the HF wave from the density deviations. Density impulses propagate away (up and down) from electric field maxima, at the ion thermal velocity, at both turn-on and turn-off of the HF wave

  1. Projected impact of climate change on waves at Mumbai High

    Digital Repository Service at National Institute of Oceanography (India)

    Pentapatim, S.; Deo, M.C.; Kerkar, J.; Vethamony, P.

    .5), a numerical wave model of the past and future wave conditions was simulated over a 40-year period. A statistical analysis of both past and projected datasets obtained significant wave heights with a 100-year return. The comparison of wave heights...

  2. Normal human serum (HS) prevents oxidant-induced lysis of cultured endothelial cells (ECs)

    International Nuclear Information System (INIS)

    Callahan, K.S.; Harlan, J.M.

    1986-01-01

    Most studies demonstrating oxidant lysis of cultured ECs are performed in serum-free media or media containing low concentrations of bovine serum. The authors found that HS protects human and bovine ECs from lysis caused by reagent H 2 O 2 or glucose/glucose oxidase (GO)-generated H 2 O 2 . EC injury was assessed by 51 Cr release, cell detachment, or trypan blue dye exclusion. Protective HS activity was dose-dependent with concentrations greater than or equal to 25% preventing lethal injury. Cytotoxicity at 24 hrs, induced by 20 mU/ml GO, was 90.1 +/- 5.2% without HS vs 1.7 +/- 4.6% with 25% HS present (20 exp). Similar protection was observed with heparinized plasma. Of note, comparable concentrations of bovine serum were devoid of protective activity. Addition of fatty acid-free albumin to the media was also without protective effect. Preliminary characterization showed HS activity was stable to 60 0 C for 30 min, non-dialyzable at 25,000 MW cutoff, and retained in delipidated serum. The HS protection was not merely due to scavenging of exogenous H 2 O 2 as A23187-induced EC lysis was also prevented by HS. Protective activity was not reproduced by purified cerruloplasmin or transferrin. In conclusion, unidentified factor(s) present in HS protect cultured ECs from oxidant-induced lysis. Since endothelium is normally exposed to 100% plasma, the authors suggest that in vitro studies of oxidant-mediated injury be performed in the presence of HS. Factor(s) in HS may play an important role in modulating oxidant-induced vascular injury in vivo

  3. Swell-generated Set-up and Infragravity Wave Propagation Over a Fringing Coral Reef: Implications for Wave-driven Inundation of Atoll Islands

    Science.gov (United States)

    Cheriton, O. M.; Storlazzi, C. D.; Rosenberger, K. J.; Quataert, E.; van Dongeren, A.

    2014-12-01

    The Republic of the Marshall Islands is comprised of 1156 islands on 29 low-lying atolls with a mean elevation of 2 m that are susceptible to sea-level rise and often subjected to overwash during large wave events. A 6-month deployment of wave and tide gauges across two shore-normal sections of north-facing coral reef on the Roi-Namur Island on Kwajalein Atoll was conducted during 2013-2014 to quantify wave dynamics and wave-driven water levels on the fringing coral reef. Wave heights and periods on the reef flat were strongly correlated to the water levels. On the fore reef, the majority of wave energy was concentrated in the incident band (5-25 s); due to breaking at the reef crest, however, the wave energy over the reef flat was dominated by infragravity-band (25-250 s) motions. Two large wave events with heights of 6-8 m at 15 s over the fore reef were observed. During these events, infragravity-band wave heights exceeded the incident band wave heights and approximately 1.0 m of set-up was established over the innermost reef flat. This set-up enabled the propagation of large waves across the reef flat, reaching maximum heights of nearly 2 m on the innermost reef flat adjacent to the toe of the beach. XBEACH models of the instrument transects were able to replicate the incident waves, infragravity waves, and wave-driven set-up across the reef when the hydrodynamic roughness of the reef was correctly parameterized. These events led to more than 3 m of wave-driven run-up and inundation of the island that drove substantial morphological change to the beach face.

  4. Wave attenuation over the Great Barrier Reef matrix

    NARCIS (Netherlands)

    Gallop, S.; Young, I.; Ranasinghe, Ranasinghe W M R J B; Durrant, T.; Haigh, I.; Mynett, Arthur

    2015-01-01

    This is the first large-scale study of the influence of an offshore reef matrix on wave transmission. The focus was on the Great Barrier Reef (GBR), Australia, utilizing a 16 yr-record of wave height, from seven satellite altimeters. Within the GBR matrix, wave height is not strongly dependent on

  5. Physical Model Study of Wave Action in New Thomsen Harbor, Sitka, Alaska

    Science.gov (United States)

    2008-02-01

    approached from the southwest. DISCLAIMER: The contents of this report are not to be used for advertising , publication, or promotional purposes...Wave height and period for irregular wave conditions refer to Hm0 and Tp, respectively. For mono- chromatic waves, wave height is the actual height...sec, respectively. Plotted along with the Group 12 results are corresponding tests from Group 13 that used mono- chromatic waves. Looking only at

  6. Experimental Study on the WavePiston Wave Energy Converter

    DEFF Research Database (Denmark)

    Pecher, Arthur; Kofoed, Jens Peter; Angelelli, E.

    This report presents the results of an experimental study of the power performance of the WavePiston wave energy converter. It focuses mainly on evaluating the power generating capabilities of the device and the effect of the following issues: Scaling ratios PTO loading Wave height and wave period...... dependency Oblique incoming waves Distance between plates During the study, the model supplied by the client, WavePiston, has been rigorously tested as all the anticipated tests have been done thoroughly and during all tests, good quality data has been obtained from all the sensors....

  7. Asymptotic Behavior of Periodic Wave Solution to the Hirota—Satsuma Equation

    International Nuclear Information System (INIS)

    Wu Yong-Qi

    2011-01-01

    The one- and two-periodic wave solutions for the Hirota—Satsuma (HS) equation are presented by using the Hirota derivative and Riemann theta function. The rigorous proofs on asymptotic behaviors of these two solutions are given such that soliton solution can be obtained from the periodic wave solution in an appropriate limiting procedure. (general)

  8. Projected future wave climate in the NW Mediterranean Sea

    Science.gov (United States)

    Casas-Prat, M.; Sierra, J. P.

    2013-07-01

    Projected future regional wave climate scenarios at a high temporal-spatial scale were obtained for the NW Mediterranean Sea, using five combinations of regional-global circulation models. Changes in wave variables were analyzed and related to the variations of the forcing wind projections, while also evaluating the evolution of the presence of the different types of sea states. To assess the significance of the changes produced, a bootstrap-based method was proposed, which accounts for the autocorrelation of data and correctly reproduces the extremes. For the mean climate, relative changes of Hs up to ±10% were obtained, whereas they were around ±20% for the extreme climate. In mean terms, variations of Hs are similar to those associated with wind speed but are enhanced/attenuated, respectively, when fetch conditions are favorable/unfavorable. In general, most notable alterations are not in the Hs magnitude but rather in its direction. In this regard, during the winter season, it is interesting to note that the significant deviations between the results derived from the two global circulation models are larger than those between regional models. ECHAM5 simulated an enhanced west wind flow that is translated into more frequent W-NW waves, whereas the HadCM3Q3 global model gives rise to the east component, which contributes to a higher intensity and number of storms coming from such a direction and directly affects the wind-sea/swell distribution of coastal stretches that face east, like the Catalan coast. Different patterns of change were obtained during the summer when a common rise of NE-E waves was found.

  9. The correlation between hs C-reactive protein and left ventricular mass in obese women

    Directory of Open Access Journals (Sweden)

    Idrus Alwi

    2006-06-01

    Full Text Available Plasma C-reactive protein (CRP concentrations are increased in obese individuals. In this study, we examined the correlation between hsCRP and left ventricular mass (LV mass. Fourty five healthy obese women and fourty five healthy non obese women as the controls group were studied by echocardiography and hsCRP. There was no significant correlation between hsCRP and left ventricular mass in obese women (r = 0.29, p 0.06. There was a significant correlation between hs CRP and body mass index (r = 0.46, p 0,002, and also hsCRP and visceral fat (r= 0.33, p 0.03. (Med J Indones 2006; 15:100-4 Keywords: hs C-reactive protein, LV mass, obese women

  10. Functional annotation of the genome unravels probiotic potential of Bacillus coagulans HS243.

    Science.gov (United States)

    Kapse, N G; Engineer, A S; Gowdaman, V; Wagh, S; Dhakephalkar, P K

    2018-05-30

    Spore forming Bacillus species are widely used as probiotics for human dietary supplements and in animal feeds. However, information on genetic basis of their probiotic action is obscure. Therefore, the present investigation was undertaken to elucidate probiotic traits of B. coagulans HS243 through its genome analysis. Genome mining revealed the presence of an arsenal of marker genes attributed to genuine probiotic traits. In silico analysis of HS243 genome revealed the presence of multi subunit ATPases, ADI pathway genes, chologlycine hydrolase, adhesion proteins for surviving and colonizing harsh gastric transit. HS243 genome harbored vitamin and essential amino acid biosynthetic genes, suggesting the use of HS243 as a nutrient supplement. Bacteriocin producing genes highlighted the disease preventing potential of HS243. Thus, this work established that HS243 possessed the genetic repertoire required for surviving harsh gastric transit and conferring health benefits to the host which were further validated by wet lab evidences. Copyright © 2018. Published by Elsevier Inc.

  11. Wind-Driven Waves in Tampa Bay, Florida

    Science.gov (United States)

    Gilbert, S. A.; Meyers, S. D.; Luther, M. E.

    2002-12-01

    Turbidity and nutrient flux due to sediment resuspension by waves and currents are important factors controlling water quality in Tampa Bay. During December 2001 and January 2002, four Sea Bird Electronics SeaGauge wave and tide recorders were deployed in Tampa Bay in each major bay segment. Since May 2002, a SeaGauge has been continuously deployed at a site in middle Tampa Bay as a component of the Bay Regional Atmospheric Chemistry Experiment (BRACE). Initial results for the summer 2002 data indicate that significant wave height is linearly dependent on wind speed and direction over a range of 1 to 12 m/s. The data were divided into four groups according to wind direction. Wave height dependence on wind speed was examined for each group. Both northeasterly and southwesterly winds force significant wave heights that are about 30% larger than those for northwesterly and southeasterly winds. This difference is explained by variations in fetch due to basin shape. Comparisons are made between these observations and the results of a SWAN-based model of Tampa Bay. The SWAN wave model is coupled to a three-dimensional circulation model and computes wave spectra at each model grid cell under observed wind conditions and modeled water velocity. When SWAN is run without dissipation, the model results are generally similar in wave period but about 25%-50% higher in significant wave height than the observations. The impact of various dissipation mechanisms such as bottom drag and whitecapping on the wave state is being investigated. Preliminary analyses on winter data give similar results.

  12. Vegetable and Fruit Intakes Are Associated with hs-CRP Levels in Pre-Pubertal Girls

    Directory of Open Access Journals (Sweden)

    Pilar Navarro

    2017-03-01

    Full Text Available The influence of diet on inflammation in children remains unclear. We aimed to analyze the influence of diet on high-sensitivity C-reactive protein (hs-CRP levels in a pre-pubertal population free of other influences that may affect hs-CRP levels. We determined hs-CRP levels in 571 six- to eight-year-old children using an hs-CRP ELISA kit. Information on food and nutrient intake was obtained through a food-frequency questionnaire. Overall dietary quality was assessed using the Healthy Eating Index (HEI. We found that girls in the highest tertile of hs-CRP levels had a higher intake of saturated fatty acid, and lower intakes of fiber and vitamin E and a lower HEI score when compared to those in tertiles 1 and 2. We also observed a significant decrease in fruit and vegetable intakes by hs-CRP tertile. Factor analysis showed that a dietary pattern that was loaded most strongly with vegetable, fruit, fiber and vitamin A and E intakes correlated negatively (−0.132, p < 0.05 with hs-CRP. No such association was found in boys. In conclusion, our data show that girls with a poorer quality diet show higher hs-CRP levels already at a pre-pubertal age.

  13. Modeling wave attenuation by salt marshes in Jamaica Bay, New York, using a new rapid wave model

    Science.gov (United States)

    Marsooli, Reza; Orton, Philip M.; Mellor, George

    2017-07-01

    Using a new rapid-computation wave model, improved and validated in the present study, we quantify the value of salt marshes in Jamaica Bay—a highly urbanized estuary located in New York City—as natural buffers against storm waves. We augment the MDO phase-averaged wave model by incorporating a vegetation-drag-induced energy dissipation term into its wave energy balance equation. We adopt an empirical formula from literature to determine the vegetation drag coefficient as a function of environmental conditions. Model evaluation using data from laboratory-scale experiments show that the improved MDO model accurately captures wave height attenuation due to submerged and emergent vegetation. We apply the validated model to Jamaica Bay to quantify the influence of coastal-scale salt marshes on storm waves. It is found that the impact of marsh islands is largest for storms with lower flood levels, due to wave breaking on the marsh island substrate. However, the role of the actual marsh plants, Spartina alterniflora, grows larger for storms with higher flood levels, when wave breaking does not occur and the vegetative drag becomes the main source of energy dissipation. For the latter case, seasonality of marsh height is important; at its maximum height in early fall, S. alterniflora causes twice the reduction as when it is at a shorter height in early summer. The model results also indicate that the vegetation drag coefficient varies 1 order of magnitude in the study area, and suggest exercising extra caution in using a constant drag coefficient in coastal wetlands.

  14. Meteo-marine parameters for highly variable environment in coastal regions from satellite radar images

    Science.gov (United States)

    Pleskachevsky, A. L.; Rosenthal, W.; Lehner, S.

    2016-09-01

    The German Bight of the North Sea is the area with highly variable sea state conditions, intensive ship traffic and with a high density of offshore installations, e.g. wind farms in use and under construction. Ship navigation and the docking on offshore constructions is impeded by significant wave heights HS > 1.3 m. For these reasons, improvements are required in recognition and forecasting of sea state HS in the range 0-3 m. Thus, this necessitates the development of new methods to determine the distribution of meteo-marine parameters from remote sensing data with an accuracy of decimetres for HS. The operationalization of these methods then allows the robust automatic processing in near real time (NRT) to support forecast agencies by providing validations for model results. A new empirical algorithm XWAVE_C (C = coastal) for estimation of significant wave height from X-band satellite-borne Synthetic Aperture Radar (SAR) data has been developed, adopted for coastal applications using TerraSAR-X (TS-X) and Tandem-X (TD-X) satellites in the German Bight and implemented into the Sea Sate Processor (SSP) for fully automatic processing for NRT services. The algorithm is based on the spectral analysis of subscenes and the model function uses integrated image spectra parameters as well as local wind information from the analyzed subscene. The algorithm is able to recognize and remove the influence of non-sea state produced signals in the Wadden Sea areas such as dry sandbars as well as nonlinear SAR image distortions produced by e.g. short wind waves and breaking waves. Also parameters of very short waves, which are not visible in SAR images and produce only unsystematic clutter, can be accurately estimated. The SSP includes XWAVE_C, a pre-filtering procedure for removing artefacts such as ships, seamarks, buoys, offshore constructions and slicks, and an additional procedure performing a check of results based on the statistics of the whole scene. The SSP allows an

  15. RoHS Compliance - Is the Global Electronics Industry Ready?

    OpenAIRE

    Head, Marieke; Hróarsson, Hallur

    2006-01-01

    RoHS is an EU directive that was proposed along with the WEEE Directive in 2002 as a part of a plan to promote extended producer responsibility within the electronics industry. Together, these two directives seek to make electrical and electronic equipment easier to manage both in terms of environmental impacts and recycling. The RoHS Directive seeks to remove lead, cadmium, mercury, hexavalent chromium and two brominated flame retardants from all consumer electrical equipment. This paper dea...

  16. Long-Term Changes in the Extreme Significant Wave Heights on the Western North Pacific: Impacts of Tropical Cyclone Activity and ENSO

    Science.gov (United States)

    Yang, Sinil; Oh, Jaiho

    2018-02-01

    Seasonal extreme wave statistics were reproduced by using the 25-km-grid global wave model of WAVEWATCH-III. The results showed that the simulated wave dataset for the present climate (1979-2009) was similar to Climate Forecast System Reanalysis (CFSR) wave data. Statistics such as the root mean squared error (RMSE) and correlation coefficient (CC) over the western North Pacific (WNP) basin were 0.5 m and 0.69 over the analysis domain. The largest trends and standard deviation were around the southern coast of Japan and western edge of the WNP. Linear regression analysis was employed to identify the relationship between the leading principal components (PCs) of significant wave heights (SWHs) in the peak season of July to September and sea surface temperature (SST) anomalies in the equatorial Pacific. The results indicated that the inter-annual variability of SWH can be associated with the El Niño-Southern Oscillation in the peak season. The CC between the first PC of the SWH and anomalies in the Nino 3.4 SST index was also significant at a 99% confidence level. Significant variations in the SWH are affected by tropical cyclones (TCs) caused by increased SST anomalies. The genesis and development of simulated TCs can be important to the variation in SWHs for the WNP in the peak season. Therefore, we can project the variability of SWHs through TC activity based on changes in SST conditions for the equatorial Pacific in the future.

  17. VHF radar observations of gravity waves at a low latitude

    Directory of Open Access Journals (Sweden)

    G. Dutta

    1999-08-01

    Full Text Available Wind observations made at Gadanki (13.5°N by using Indian MST Radar for few days in September, October, December 1995 and January, 1996 have been analyzed to study gravity wave activity in the troposphere and lower stratosphere. Horizontal wind variances have been computed for gravity waves of period (2-6 h from the power spectral density (PSD spectrum. Exponential curves of the form eZ/H have been fitted by least squares technique to these variance values to obtain height variations of the irregular winds upto the height of about 15 km, where Z is the height in kilometers. The value of H, the scale height, as determined from curve fitting is found to be less than the theoretical value of scale height of neutral atmosphere in this region, implying that the waves are gaining energy during their passage in the troposphere. In other words, it indicates that the sources of gravity waves are present in the troposphere. The energy densities of gravity wave fluctuations have been computed. Polynomial fits to the observed values show that wave energy density increases in the troposphere, its source region, and then decreases in the lower stratosphere.Key words. Meteorology and atmospheric dynamics (middle atmosphere dynamics; turbulence; waves and tides

  18. Comments on ‘Temporal significant wave height estimation from wind speed by perceptron Kalman filtering’ by A. Altunkaynak and M. Ozger, Ocean Engineering, Vol. 31(10); 2004,1245-1255

    Digital Repository Service at National Institute of Oceanography (India)

    Mandal, S.

    wind speed. Interestingly the PKF model is a two layered network (input and output) without hidden layer. Also it is a fact that numerical or physical models have restrictions by certain assumptions and conditions, whereas artificial neural network... is shown by Tsai et al (2002). They have carried out forecasting of significant wave heights and periods at a desired location directly from the observed wave records using a supervised artificial neural network with error back-propagation procedures...

  19. Spectral Wave Characteristics in the Nearshore Waters of Northwestern Bay of Bengal

    Science.gov (United States)

    Anjali Nair, M.; Sanil Kumar, V.; Amrutha, M. M.

    2018-03-01

    The spectral wave characteristics in the nearshore waters of northwestern Bay of Bengal are presented based on the buoy-measured data from February 2013 to December 2015 off Gopalpur at 15-m water depth. The mean seasonal significant wave height and mean wave period indicate that the occurrence of higher wave heights and wave periods is during the southwest monsoon period (June-September). 74% of the sea surface height variance in a year is a result of waves from 138 to 228° and 16% are from 48 to 138°. Strong inter-annual variability is observed in the monthly average wave parameters due to the occurrence of tropical cyclones. Due to the influence of the tropical cyclone Phailin, maximum significant wave height of 6.7 m is observed on 12 October 2013 and that due to tropical cyclone Hudhud whose track is 250 southwest of the study location is 5.84 m on 12 October 2014. Analysis revealed that a single tropical cyclone influenced the annual maximum significant wave height and not the annual average value which is almost same ( 1 m) in 2014 and 2015. The waves in the northwestern Bay of Bengal are influenced by the southwest and northeast monsoons, southern ocean swells and cyclones.

  20. Trend analysis of the wave storminess: the wave direction

    Science.gov (United States)

    Casas Prat, M.; Sierra, J. P.; Mösso, C.; Sánchez-Arcilla, A.

    2009-09-01

    Climate change has an important role in the current scientific research because of its possible future negative consequences. Concerning the climate change in the coastal engineering field, the apparent sea level rise is one of the key parameters as well as the wave height and the wave direction temporal variations. According to the IPCC (2007), during the last century the sea level has been increasing with a mean rate of 1.7 ± 0.5 mm/yr. However, at local/regional scale the tendency significantly differs from the global trend since the local pressure and wind field variations become more relevant. This appears to be particularly significant in semi-enclosed areas in the Mediterranean Sea (Cushman-Roisin et al., 2001). Even though the existing unsolved questions related to the sea level rise, the uncertainty concerning the wave height is even larger, in which stormy conditions are especially important because they are closely related to processes such as coastal erosion, flooding, etc. Therefore, it is necessary to identify possible existing tendencies of storm related parameters. In many studies, only the maximum wave height and storm duration are analysed, remaining the wave direction in a second term. Note that a possible rotation of the mean wave direction may involve severe consequences since most beach and harbour defence structures have been designed assuming a constant predominant wave incidence. Liste et al. (2004) illustrated this fact with an example in which a rotation of only 2 degrees of the mean energy flux vector could produce a beach retreat of 20 m. Another possible consequence would be a decrease of the harbour operability: increased frequency of storms in the same direction as the harbour entrance orientation would influence the navigability. The present study, which focuses in the Catalan coast (NW Mediterranean Sea), aims to improve the present knowledge of the wave storminess variations at regional scale, specially focusing on the wave

  1. Assimilation of satellite data to increase the reliability of the wave predictions in the Black Sea

    Science.gov (United States)

    Rusu, Liliana; Raileanu, Alina

    2015-04-01

    In order to improve the wave predictions provided in the Black Sea by a wave modelling system based on the SWAN (Simulating Waves Nearshore) spectral model, a technique for assimilating the satellite data has been implemented and evaluated. For this purpose, an approach based on the Optimal Interpolation method has been considered and its results are discussed in the present work. As a first step, SWAN model simulations have been carried out for a 5-year interval (2004-2008). The assimilation is made in terms of the significant wave height (Hs) for each 24 hours considering data coming from 4 satellites (ERS-2, JASON-1, JASON-2, GEOSAT Follow-On). Subsequently, data provided by two other satellites (ENVISAT and TOPEX) are used for validations. To assess the improvement brought in the model predictions by the assimilation scheme, a comparison has been performed between the model results with and without assimilation. The statistical parameters evaluated are: bias, mean absolute error, RMS error, scatter index, correlation coefficient and symmetric slope. The results show that the data assimilation procedure induces a significant improvement of the statistical parameters (lower values for bias, errors and scatter index and values closer to the unity of the correlation coefficient and for the symmetric slope). It was found also that an important factor in improving the wave predictions is represented by the value of the correlation length accounted for the Hs prediction errors (Lmax). Previous studies indicate for this length a value around four degrees in the vicinity of 45 degrees latitude (which corresponds also to the basin of the Black Sea). This value was first considered in the assimilation technique. On the other hand, taking also into account the fact that in the Black Sea the wind-sea waves are dominant, lower values for the parameter Lmax were tested as well and it seems that the most appropriate value for this parameter is between three and four degrees

  2. Developing competitive marketing and sales strategy for HS-Eden

    OpenAIRE

    Dragusha, Cajup

    2016-01-01

    Start-ups are faced with variety of challenges and uncertainty therefore comprehensive marketing and sales strategy must be in place to make sure that limited resources are spend wisely in order to minimize uncertainty and pave a path that would lead to successful business. HS Eden is a new-start-up venture created in Lappeenranta University of Technology with an ambition to develop AMB systems for commercial use. The aim of this study was to build a marketing and sales strategy to help HS-Ed...

  3. Measuring the height-to-height correlation function of corrugation in suspended graphene

    International Nuclear Information System (INIS)

    Kirilenko, D.A.; Brunkov, P.N.

    2016-01-01

    Nanocorrugation of 2D crystals is an important phenomenon since it affects their electronic and mechanical properties. The corrugation may have various sources; one of them is flexural phonons that, in particular, are responsible for the thermal conductivity of graphene. A study of corrugation of just the suspended graphene can reveal much of valuable information on the physics of this complicated phenomenon. At the same time, the suspended crystal nanorelief can hardly be measured directly because of high flexibility of the 2D crystal. Moreover, the relief portion related to rapid out-of-plane oscillations (flexural phonons) is also inaccessible by such measurements. Here we present a technique for measuring the Fourier components of the height–height correlation function H(q) of suspended graphene which includes the effect of flexural phonons. The technique is based on the analysis of electron diffraction patterns. The H(q) is measured in the range of wavevectors q≈0.4–4.5 nm"−"1. At the upper limit of this range H(q) does follow the T/κq"4 law. So, we measured the value of suspended graphene bending rigidity κ=1.2±0.4 eV at ambient temperature T≈300 K. At intermediate wave vectors, H(q) follows a slightly weaker exponent than theoretically predicted q"−"3"."1"5 but is closer to the results of the molecular dynamics simulation. At low wave vectors, the dependence becomes even weaker, which may be a sign of influence of charge carriers on the dynamics of undulations longer than 10 nm. The technique presented can be used for studying physics of flexural phonons in other 2D materials. - Highlights: • A technique for measuring free-standing 2D crystal corrugation is proposed. • The height-to-height correlation function of the suspended graphene corrugation is measured. • Various parameters of the intrinsic graphene properties are experimentally determined.

  4. Solutol HS 15, nontoxic polyoxyethylene esters of 12-hydroxystearic acid, reverses multidrug resistance.

    Science.gov (United States)

    Coon, J S; Knudson, W; Clodfelter, K; Lu, B; Weinstein, R S

    1991-02-01

    A recently developed non-ionic surfactant called Solutol HS 15 (poly-oxyethylene esters of 12-hydroxystearic acid), with low toxicity in vivo, was shown to reverse completely the multidrug resistance of KB 8-5 and KB 8-5-11 human epidermoid carcinoma cells in vitro but did not potentiate drug toxicity in drug-sensitive KB 3-1 cells. At a concentration of 10% of its own IC50 (mean concentration of drug that causes 50% inhibition of cell growth compared to controls), Solutol HS 15 produced a 35-, 28-, and 42-fold reduction in the resistance of KB 8-5-11 cells to colchicine, vinblastine, and doxorubicin, respectively. Solutol HS 15 was relatively much more potent than the prototypic reversing agent, verapamil, for reversing colchicine resistance, compared to the ability of each agent to reverse colchicine resistance, compared to the ability of each agent to reverse vinblastine resistance. Like verapamil, Solutol HS 15 promoted a 50-fold accumulation of rhodamine 123 in KB 8-5-11 cells, as measured by flow cytometry. Also, Solutol HS 15 and verapamil reduced the efflux of rhodamine 123 from KB 8-5-11 cells previously loaded with rhodamine 123 to a similar low rate. Solutol HS 15 did not affect the transport of alanine or glucose into KB 8-5-11 cells, indicating that its effect upon membrane active transport is not entirely nonspecific. Considering their different structure and different relative potency for reversing colchicine resistance, Solutol HS 15 and verapamil probably reverse multidrug resistance by different mechanisms. Solutol HS 15 merits consideration as a potential therapeutic agent because of its effectiveness for reversing multidrug resistance in vitro and its low toxicity in vivo.

  5. Laboratory Tests in the Development of WaveCat

    Directory of Open Access Journals (Sweden)

    James Allen

    2016-12-01

    Full Text Available WaveCat, a novel overtopping Wave Energy Converter, was tested with the aim of determining its performance under different sea states, establishing a starting point for optimisation of the device, numerical model validation and proof-of-concept for the control systems. The tests were carried out at a 1:30 scale in the Ocean Basin of the COAST Laboratory at University of Plymouth. A state-of-the-art control system was implemented, and overtopping rates and device motions were recorded alongside the wave field. It was observed that power generation is dependent on both the wave height and period, with smaller periods tending to produce greater overtopping rates, and therefore greater power generation, for the same wave height. Due to time constraints in the laboratory, only one configuration of draft/freeboard was tested; with this configuration, overtopping occurred under significant wave heights of 0.083 m or more, corresponding to 2.5 m or more in prototype values. These experimental results form the basis for future development and optimisation of WaveCat.

  6. Seasonal variability in virtual height of ionospheric f/sub 2/ layer at the pakistan atmospheric region

    International Nuclear Information System (INIS)

    Jilani, A.A.; Afridi, F.A.K.; Mian, K.; Zai, M.A.K.Y.

    2013-01-01

    The aim of this study was to assess the seasonal variability in virtual height of ionospheric F/sub 2/ layer for Pakistan's atmospheric region (PAR). In this communication virtual height variations have been analyzed by the descriptive statistical techniques. These methodologies comprise an autoregressive strategy, linear regression and polynomial regression. The relevance of these models has been illuminated using predicted values of different parameters under the seasonal variation of ionospheric F/sub 2/ layer in virtual height that affect the radio wave propagation through the ionosphere. These techniques are implemented to theorize the physical process of varying the virtual heights that leads this study towards formulating the variations due to interaction of radio wave propagation with this ionospheric layer. (author)

  7. TAPCHAN Wave Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    1983-10-01

    The Tapered Channel Wave Power Plant (TAPCHAN) is based on a new method for wave energy conversion. The principle of operation can be explained by dividing the system into the following four sub-systems: Firstly, a collector which is designed to concentrate the water energy and optimize collection efficiency for a range of frequencies and directions. Secondly, the energy converter, in which the energy of the collected waves is transformed into potential energy in an on-shore water reservoir. This is the unique part of the power plant. It consists of a gradually narrowing channel with wall heights equal to the filling level of the reservoir (typical heights 3-7 m). The waves enter the wide end of the channel and as they propagate down the narrowing channel, the wave height is amplified until the wavecrests spill over the walls. Thirdly, a reservoir which provides a stable water supply for the turbines. Finally, the hydroelectric power plant, where well established techniques are used for the generation of electric power. The water turbine driving the electric generator is of a low head type, such as a Kaplan or a tubular turbine. It must be designed for salt water operation and should have good regulation capabilities. Power plants based on the principle described, are now offered on a commercial basis.

  8. Association of HS6ST3 gene polymorphisms with obesity and ...

    Indian Academy of Sciences (India)

    The heparan sulfate 6-O-sulfotransferase 3 (HS6ST3) gene is involved in heparan sulphate and heparin metabolism, and has been reported to be associated with diabetic retinopathy in type 2 diabetes. We hypothesized that HS6ST3 gene polymorphisms might play an important role in obesity and related phenotypes (such ...

  9. Surf similarity and solitary wave runup

    DEFF Research Database (Denmark)

    Fuhrman, David R.; Madsen, Per A.

    2008-01-01

    The notion of surf similarity in the runup of solitary waves is revisited. We show that the surf similarity parameter for solitary waves may be effectively reduced to the beach slope divided by the offshore wave height to depth ratio. This clarifies its physical interpretation relative to a previ...... functional dependence on their respective surf similarity parameters. Important equivalencies in the runup of sinusoidal and solitary waves are thus revealed.......The notion of surf similarity in the runup of solitary waves is revisited. We show that the surf similarity parameter for solitary waves may be effectively reduced to the beach slope divided by the offshore wave height to depth ratio. This clarifies its physical interpretation relative...... to a previous parameterization, which was not given in an explicit form. Good coherency with experimental (breaking) runup data is preserved with this simpler parameter. A recasting of analytical (nonbreaking) runup expressions for sinusoidal and solitary waves additionally shows that they contain identical...

  10. Rogue Waves in the Ocean

    Science.gov (United States)

    Waseda, Takuji

    2010-03-01

    Giant episodic ocean waves that suddenly soar like a wall of water out of an otherwise calm sea are not just a legend. Such waves—which in the past have been called “abnormal,” “exceptional,” “extreme,” and even “vicious killer” waves—are now commonly known as “rogue waves” or “freak waves.” These waves have sunk or severely damaged 22 supercarriers in the world and caused the loss of more than 500 lives in the past 40 years. The largest wave registered by reliable instruments reached 30 meters in height, and the largest wave recorded by visual observation reached about 34 meters, equivalent to the height of an eight-story building. Tales of seafarers from Christopher Columbus to the passengers of luxury cruise ships had long been undervalued by scientists, but in the past 10 or so years, those historical notes and modern testimonies have been scientifically dissected to reveal the nature of these monster waves.

  11. The Antifungal Plant Defensin HsAFP1 Is a Phosphatidic Acid-Interacting Peptide Inducing Membrane Permeabilization

    Directory of Open Access Journals (Sweden)

    Tanne L. Cools

    2017-11-01

    Full Text Available HsAFP1, a plant defensin isolated from coral bells (Heuchera sanguinea, is characterized by broad-spectrum antifungal activity. Previous studies indicated that HsAFP1 binds to specific fungal membrane components, which had hitherto not been identified, and induces mitochondrial dysfunction and cell membrane permeabilization. In this study, we show that HsAFP1 reversibly interacts with the membrane phospholipid phosphatidic acid (PA, which is a precursor for the biosynthesis of other phospholipids, and to a lesser extent with various phosphatidyl inositol phosphates (PtdInsP’s. Moreover, via reverse ELISA assays we identified two basic amino acids in HsAFP1, namely histidine at position 32 and arginine at position 52, as well as the phosphate group in PA as important features enabling this interaction. Using a HsAFP1 variant, lacking both amino acids (HsAFP1[H32A][R52A], we showed that, as compared to the native peptide, the ability of this variant to bind to PA and PtdInsP’s is reduced (≥74% and the antifungal activity of the variant is reduced (≥2-fold, highlighting the link between PA/PtdInsP binding and antifungal activity. Using fluorescently labelled HsAFP1 in confocal microscopy and flow cytometry assays, we showed that HsAFP1 accumulates at the cell surface of yeast cells with intact membranes, most notably at the buds and septa. The resulting HsAFP1-induced membrane permeabilization is likely to occur after HsAFP1’s internalization. These data provide novel mechanistic insights in the mode of action of the HsAFP1 plant defensin.

  12. Poly(lactic-co-glycolic) Acid/Solutol HS15-Based Nanoparticles for Docetaxel Delivery.

    Science.gov (United States)

    Cho, Hyun-Jong; Park, Ju-Hwan; Kim, Dae-Duk; Yoon, In-Soo

    2016-02-01

    Docetaxel (DCT) is one of anti-mitotic chemotherapeutic agents and has been used for the treatment of gastric cancer as well as head and neck cancer, breast cancer and prostate cancer. Poly(lactic- co-glycolic) acid (PLGA) is one of representative biocompatible and biodegradable polymers, and polyoxyl 15 hydroxystearate (Solutol HS15) is a nonionic solubilizer and emulsifying agent. In this investigation, PLGA/Solutol HS15-based nanoparticles (NPs) for DCT delivery were fabricated by a modified emulsification-solvent evaporation method. PLGA/Solutol HS15/DCT NPs with about 169 nm of mean diameter, narrow size distribution, negative zeta potential, and spherical morphology were prepared. The results of solid-state studies revealed the successful dispersion of DCT in PLGA matrix and its amorphization during the preparation process of NPs. According to the result of in vitro release test, emulsifying property of Solutol HS15 seemed to contribute to the enhanced drug release from NPs at physiological pH. All these findings imply that developed PLGA/Solutol HS15-based NP can be a promising local anticancer drug delivery system for cancer therapy.

  13. Linking source region and ocean wave parameters with the observed primary microseismic noise

    Science.gov (United States)

    Juretzek, C.; Hadziioannou, C.

    2017-12-01

    In previous studies, the contribution of Love waves to the primary microseismic noise field was found to be comparable to those of Rayleigh waves. However, so far only few studies analysed both wave types present in this microseismic noise band, which is known to be generated in shallow water and the theoretical understanding has mainly evolved for Rayleigh waves only. Here, we study the relevance of different source region parameters on the observed primary microseismic noise levels of Love and Rayleigh waves simultaneously. By means of beamforming and correlation of seismic noise amplitudes with ocean wave heights in the period band between 12 and 15 s, we analysed how source areas of both wave types compare with each other around Europe. The generation effectivity in different source regions was compared to ocean wave heights, peak ocean gravity wave propagation direction and bathymetry. Observed Love wave noise amplitudes correlate comparably well with near coastal ocean wave parameters as Rayleigh waves. Some coastal regions serve as especially effective sources for one or the other wave type. These coincide not only with locations of high wave heights but also with complex bathymetry. Further, Rayleigh and Love wave noise amplitudes seem to depend equally on the local ocean wave heights, which is an indication for a coupled variation with swell height during the generation of both wave types. However, the wave-type ratio varies directionally. This observation likely hints towards a spatially varying importance of different source mechanisms or structural influences. Further, the wave-type ratio is modulated depending on peak ocean wave propagation directions which could indicate a variation of different source mechanism strengths but also hints towards an imprint of an effective source radiation pattern. This emphasizes that the inclusion of both wave types may provide more constraints for the understanding of acting generation mechanisms.

  14. Accuracy of visual wave observation from merchant ships and estimated wave loads; Accuracy of visual wave observation from merchant ships and estimated wave loads

    Energy Technology Data Exchange (ETDEWEB)

    Kawabe, H. [National Defense Academy, Kanagawa (Japan); Masaoka, K. [University of Osaka Prefecture, Osaka (Japan). Faculty of Engineering

    1998-06-01

    There is a large number of studies on discussions concerning accuracy of visual observation of waves and the correction method thereon. This paper give considerations on observation accuracy placing a viewpoint on that by merchant ships. Based on ship meteorological observation tables reported to the Meteorological Agency of Japan on meteorology in North Pacific during 14 years from 1976 to1989, wave observation values taken by merchant ships and observation ships were compared statistically to investigate the accuracy of visual wave observations carried out by merchant ships. With regard to wave heights, the observation values taken by the observation ships and the merchant ships have strong correlation, where the merchant ships evaluate them somewhat higher than the observation ships. Regarding wave cycles of wind waves, the merchant ships tend to have the observation values on longer cycle side. Correlation between the observations values by the merchant ships and the observation ships is weak both in wind waves and swells. There is not much of variation in accuracy of observations during daytime and at night performed by the merchant ships. It will be necessary in the future to give considerations on a method to correct the observation values on wave cycles taken by the merchant ship, and on a correction method in which both of the wave cycles and the wave heights are corrected simultaneously to make the observation values of the merchant ship equal to those of the observation ships. Thus, the observation values reported by general merchant ships in a large number every year will have to be utilized more effectively. 11 refs., 21 figs., 2 tabs.

  15. Wave kinematics and response of slender offshore structures. Vol 4: Wave kinematics

    Energy Technology Data Exchange (ETDEWEB)

    Riber, H.J.

    1999-08-01

    The kinematics of large surface waves has been measured by means of sonar's placed on the sea floor at the Tyra field. Measurements from the most severe storm are analysed and extreme wave velocity profiles are compared to Stoke wave velocity profiles. Statistical distributions of crest velocity and wave celerity are presented. The analysis shows how the deviation from the Stokes prediction varies with wave heights and steepness. Analyses of the directional wave field leads to the conclusion that the extreme waves are three-dimensional. It is shown that the peculiar kinematics of extreme waves is of great relevance to the design of jacket type structures. (au)

  16. Effect of the administration time of HS6101 on hematopoietic recovery in ICR mice injured by cyclophosphamide

    Directory of Open Access Journals (Sweden)

    Shuang XING

    2015-06-01

    Full Text Available Objective To explore the effect of the administration time of HS6101 on hematopoietic recovery in ICR mice injured by cyclophosphamide (CTX. Methods One hundred and three male ICR mice were divided into 4 groups: CTX control, HS6101 prevention, HS6101 treatment, and HS6101 prevention+treatment groups. CTX was intraperitoneally injected into the ICR mice at a dose of 100mg/(kg.d for three consecutive days to establish a chemotherapeutics-injured model. HS6101 at a dose of 27μg/mouse in 0.2ml was subcutaneously injected into the mice 1h before the first administration of CTX in HS6101-prevention group, 1h after the last administration of CTX in HS6101 treatment group, and both at 1h before the first administration and 1h after the last administration of CTX in HS6101 prevention + treatment group. Physiological saline was subcutaneously injected into the mice in CTX control group (0.2ml/mouse. 10μl peripheral blood was collected from the caudal vein for WBC, neutrophil lymphocyte, RBC and platelet counts on day -1, 3, 5, 7, 9, 11, 13, 15, 17 with the MEK-7222K cell analyzer, and the cell count was compared between HS6101 treatment mice and CTX control mice. Another 30 male ICR mice were used for bone marrow colony forming unit (CFU assay and bone marrow histopathological examination, and they were assigned into normal control, CTX control, HS6101 prevention, HS6101treatment and HS6101 prevention + treatment groups (each n=6. On the day 4 and day 9 after CTX injection, mice were sacrificed and bone marrow cells were collected from the left femur for mononuclear cell (MNC isolation. 1×104 MNCs were planted in 1.0ml mouse CFU culture medium M3434 and cultured in incubator with the temperature of 37℃, and 5% CO2 for 7 days. After that, granulocyte macrophage-colony-forming unit (GM-CFU, megakaryocyte colony forming unit (MK-CFU, mixture-colony-forming unit (Mix-CFU, burst-forming unit-erythroid (BFU-E and colony-forming unit-erythroid (CFU

  17. Upper atmospheric planetary-wave and gravity-wave observations

    Science.gov (United States)

    Justus, C. G.; Woodrum, A.

    1973-01-01

    Previously collected data on atmospheric pressure, density, temperature and winds between 25 and 200 km from sources including Meteorological Rocket Network data, ROBIN falling sphere data, grenade release and pitot tube data, meteor winds, chemical release winds, satellite data, and others were analyzed by a daily-difference method, and results on the magnitude of atmospheric perturbations interpreted as gravity waves and planetary waves are presented. Traveling planetary-wave contributions in the 25-85 km range were found to have significant height and latitudinal variation. It was found that observed gravity-wave density perturbations and wind are related to one another in the manner predicted by gravity-wave theory. It was determined that, on the average, gravity-wave energy deposition or reflection occurs at all altitudes except the 55-75 km region of the mesosphere.

  18. Serum hsCRP: A Novel Marker for Prediction of Cerebrovascular Accidents (Stroke).

    Science.gov (United States)

    Patgiri, Dibyaratna; Pathak, Mauchumi Saikia; Sharma, Pradeep; Kutum, Tridip; Mattack, Nirmali

    2014-12-01

    Strokes are caused by disruption of the blood supply to the brain. This may result from either blockage or rupture of a blood vessel. Yearly 15 million people worldwide suffer a stroke. India ranks second worldwide in terms of deaths from stroke. The incidence of stroke increases with age affecting the economically productive middle aged population. Hypertension and male sex are other risk factors for stroke. C-Reactive Protein (CRP) is an acute phase protein whose concentration rises in blood following inflammation. Formerly, assays for CRP detected its rise only after significant inflammation. However, recently developed high sensitivity assays (hsCRP) enable the measurement of CRP in individuals who are apparently healthy. Several studies indicate that hsCRP is elevated in individuals who are at risk of developing Coronary Artery Disease or Cerebrovascular events, the elevation may be found years before the first detection of vascular problems. In the absence of other biochemical markers, the present study aimed to evaluate the predictive and diagnostic role of hsCRP in stroke. The study consisted of 50 patients of acute stroke admitted in Gauhati Medical College and Hospital. The control population consisted of two groups - 50 age and sex matched controls with hypertension (Hypertensive control group) and 50 age and sex matched controls with no obvious disease constituted the Normal control group. hsCRP levels were measured in all the groups and compared statistically. hsCRP is an acute phase reactant whose concentration rises in stroke as well as in those at risk. The rise may be identified even before the appearance of risk factors. Hence, hsCRP may be useful as a predictive and diagnostic marker in stroke.

  19. Global trends in significant wave height and marine wind speed from the ERA-20CM

    Science.gov (United States)

    Aarnes, Ole Johan; Breivik, Øyvind

    2016-04-01

    The ERA-20CM is one of the latest additions to the ERA-series produced at the European Center for Medium-Range Weather Forecasts (ECMWF). This 10 member ensemble is generated with a version of the Integrated Forecast System (IFS), a coupled atmosphere-wave model. The model integration is run as a AMIP (Atmospheric Model Intercomparison Project) constrained by CMIP5 recommended radiative forcing and different realizations of sea-surface temperature (SST) and sea-ice cover (SIC) prescribed by the HadISST2 (Met Office Hadley Center). While the ERA-20CM is unable to reproduce the actual synoptic conditions, it is designed to offer a realistic statistical representation of the past climate, spanning the period 1899-2010. In this study we investigate global trends in significant wave height and marine wind speed based on ERA-20CM, using monthly mean data, upper percentiles and monthly/annual maxima. The aim of the study is to assess the quality of the trends and how these estimates are affected by different SST and SIC. Global trends are compared against corresponding estimates obtained with ERA-Interim (1979-2009), but also crosschecked against ERA-20C - an ECMWF pilot reanalysis of the 20th-century, known to most trustworthy in the Northern Hemisphere extratropics. Over the period 1900-2009, the 10 member ensemble yields trends mainly within +/- 5% per century. However, significant trends of opposite signs are found locally. Certain areas, like the eastern equatorial Pacific, highly affected by the El Niño Southern Oscillation, show stronger trends. In general, trends based on statistical quantities further into the tail of the distribution are found less reliable.

  20. Low-cost wave characterization modules for oil spill response

    Directory of Open Access Journals (Sweden)

    E.D. Skinner

    2018-06-01

    Full Text Available Marine oil spills can be remediated by mechanical skimmers in calm waters, but performance degrades with increased wave height. We have developed and demonstrated a system that quantifies local wave characteristics with an uncertainty of four inches of heave. Our system is intended for the measurement of wave characteristics during oil spill recovery. It conveys this information to coordinators and responders in real time via WiFi and remote reporting through a satellite network. This information will allow for enhanced situational awareness during an oil spill response, assisting stakeholders and optimizing mechanical skimming operations. Our wave characterization module (WCM uses accelerometer outputs from a very small inertial measurement unit (IMU to generate wave statistics and calculate wave characteristics. It is configured such that a WCM can either be attached to a skimmer float or incorporated into a microbuoy. Wave height and period are transmitted via WiFi and/or a satellite-enabled mesh-grid network to a cloud-hosted geographic information system (GIS. Here, we discuss the bare-bones sensors-plus-algorithm approach we developed by using spring-mass systems to approximate the wave height and period regime of interest. We then describe open water tests carried out using that development system both mounted to a weir skimmer mockup and packaged in a microbuoy. Finally, we present controlled tests in the wave tank at Ohmsett, the National Oil Spill Response Test Facility in New Jersey, with the WCMs communicating the wave characteristics via WiFi to tankside laptops and via satellite to the cloud-based GIS. Snapshot determinations of wave height calculated using the scalar magnitude of the three-axis accelerometer in the IMU were within four inches of the benchmark wave measurement system at Ohmsett. Keywords: Oil spill, Wave characterization module, Inertial measurement unit, Microbuoy

  1. Buoy and Generator Interaction with Ocean Waves: Studies of a Wave Energy Conversion System

    Energy Technology Data Exchange (ETDEWEB)

    Lindroth, Simon

    2011-07-01

    On March 13th, 2006, the Div. of Electricity at Uppsala Univ. deployed its first wave energy converter, L1, in the ocean southwest of Lysekil. L1 consisted of a buoy at the surface, connected through a line to a linear generator on the seabed. Since the deployment, continuous investigations of how L1 works in the waves have been conducted, and several additional wave energy converters have been deployed. This thesis is based on ten publications, which focus on different aspects of the interaction between wave, buoy, and generator. In order to evaluate different measurement systems, the motion of the buoy was measured optically and using accelerometers, and compared to measurements of the motion of the movable part of the generator - the translator. These measurements were found to correlate well. Simulations of buoy and translator motion were found to match the measured values. The variation of performance of L1 with changing water levels, wave heights, and spectral shapes was also investigated. Performance is here defined as the ratio of absorbed power to incoming power. It was found that the performance decreases for large wave heights. This is in accordance with the theoretical predictions, since the area for which the stator and the translator overlap decreases for large translator motions. Shifting water levels were predicted to have the same effect, but this could not be seen as clearly. The width of the wave energy spectrum has been proposed by some as a factor that also affects the performance of a wave energy converter, for a set wave height and period. Therefore the relation between performance and several different parameters for spectral width was investigated. It was found that some of the parameters were in fact correlated to performance, but that the correlation was not very strong. As a background on ocean measurements in wave energy, a thorough literature review was conducted. It turns out that the Lysekil project is one of quite few projects that

  2. A typical wave wake from high-speed vessels: its group structure and run-up

    Directory of Open Access Journals (Sweden)

    I. Didenkulova

    2013-02-01

    Full Text Available High-amplitude water waves induced by high-speed vessels are regularly observed in Tallinn Bay, the Baltic Sea, causing intense beach erosion and disturbing marine habitants in the coastal zone. Such a strong impact on the coast may be a result of a certain group structure of the wave wake. In order to understand it, here we present an experimental study of the group structure of these wakes at Pikakari beach, Tallinn Bay. The most energetic vessel waves at this location (100 m from the coast at the water depth 2.7 m have amplitudes of about 1 m and periods of 8–10 s and cause maximum run-up heights on a beach up to 1.4 m. These waves represent frequency modulated packets where the largest and longest waves propagate ahead of other smaller amplitude and period waves. Sometimes the groups of different heights and periods can be separated even within one wave wake event. The wave heights within a wake are well described by the Weibull distribution, which has different parameters for wakes from different vessels. Wave run-up heights can also be described by Weibull distribution and its parameters can be connected to the parameters of the distribution of wave heights 100 m from the coast. Finally, the run-up of individual waves within a packet is studied. It is shown that the specific structure of frequency modulated wave packets, induced by high-speed vessels, leads to a sequence of high wave run-ups at the coast, even when the original wave heights are rather moderate. This feature can be a key to understanding the significant impact on coasts caused by fast vessels.

  3. Evaluation of Usefulness of hs-CRP and Ferritin Assays in Patients with Nasal Polyps

    Directory of Open Access Journals (Sweden)

    Robert Partyka

    2014-01-01

    Full Text Available Background. Chronic nature of the nasal polyps, tendency to recurrence, and lack of satisfying treatment need the diagnostic’s parameters which show early inflammatory state as ferritin and hs-CRP. The Aim of Study. Assessment of hs-CRP and ferritin blood levels in nasal polyps patients in evaluation of treatment efficacy. Methods. All 38 patients were divided into 2 groups. Group I included 19 patients with anti-inflammatory therapy 2 weeks after surgery. Group II included 19 patients without anti-inflammatory therapy 2 weeks after surgery. The levels of hs-CRP and ferritin have been assessed before and 2 and 6 weeks after surgical treatment. Results. Research showed statistically significant difference of ferritin’s concentration between examined groups 6 weeks after surgery (P<0.05 and statistically significant difference of hs-CRP concentration 2 and 6 weeks after surgery (P<0.05. Conclusion. (1 The analysis of serum ferritin and hs-CRP concentrations can be useful in early postoperative detection of inflammatory state in patients with nasal polyps and for the effectiveness of therapy. (2 Lack of correlation between mean ferritin and hs-CRP serum levels, at each diagnostic and monitoring stage, shows that they are independent and cannot be determined interchangeably.

  4. The Damage To The Armour Layer Due To Extreme Waves

    Science.gov (United States)

    Oztunali Ozbahceci, Berguzar; Ergin, Aysen; Takayama, Tomotsuka

    2010-05-01

    The sea waves are not regular but random and chaotic. In order to understand this randomness, it is common to make individual wave analysis in time domain or spectral analysis in frequency domain. Characteristic wave heights like Hmax, H%2,H1-10, H1-3, Hmean are obtained through individual wave analysis in time domain. These characteristic wave heights are important because they are used in the design of different type of coastal structures. It is common to use significant wave height, H1-3,for the design of rubble mound structures. Therefore, only spectrally derived or zero-crossing significant wave height is usually reported for the rubble mound breakwaters without any information on larger waves. However, even the values of H1-3are similar; some train of irregular waves may exhibit a large fluctuation of instantaneous wave energy, while another train may not show such a fluctuation (Goda, 1998). Moreover, freak or rogue wave, simply defined as the wave exceeding at least twice the significant wave height may also occur. Those larger waves were called as extreme waves in this study and the effect of extreme waves on the damage to the armour layer of rubble mound breakwaters was investigated by means of hydraulic model experiment. Rock armored rubble mound breakwater model with 1:1.5 slope was constructed in the wave channel of Hydraulics Laboratory of the Disaster Prevention Research Institute of Kyoto University, Japan. The model was consisted of a permeable core layer, a filter and armour layer with two stones thicknesses. Size of stones were same for both of the slopes as Dn50(armour)=0.034m, Dn50(filter)=0.021m and Dn50(core)=0.0148m for armour, filter and core layers, respectively. Time series which are approximately equal to 1000 waves, with similar significant wave height but different extreme wave height cases were generated. In order to generate necessary time series in the wave channel, they were firstly computed by numerically. For the numerical

  5. Waves in the Red Sea: Response to monsoonal and mountain gap winds

    KAUST Repository

    Ralston, David K.

    2013-08-01

    An unstructured grid, phase-averaged wave model forced with winds from a high resolution atmospheric model is used to evaluate wind wave conditions in the Red Sea over an approximately 2-year period. The Red Sea lies in a narrow rift valley, and the steep topography surrounding the basin steers the dominant wind patterns and consequently the wave climate. At large scales, the model results indicated that the primary seasonal variability in waves was due to the monsoonal wind reversal. During the winter, monsoon winds from the southeast generated waves with mean significant wave heights in excess of 2. m and mean periods of 8. s in the southern Red Sea, while in the northern part of the basin waves were smaller, shorter period, and from northwest. The zone of convergence of winds and waves typically occurred around 19-20°N, but the location varied between 15 and 21.5°N. During the summer, waves were generally smaller and from the northwest over most of the basin. While the seasonal winds oriented along the axis of the Red Sea drove much of the variability in the waves, the maximum wave heights in the simulations were not due to the monsoonal winds but instead were generated by localized mountain wind jets oriented across the basin (roughly east-west). During the summer, a mountain wind jet from the Tokar Gap enhanced the waves in the region of 18 and 20°N, with monthly mean wave heights exceeding 2. m and maximum wave heights of 14. m during a period when the rest of the Red Sea was relatively calm. Smaller mountain gap wind jets along the northeast coast created large waves during the fall and winter, with a series of jets providing a dominant source of wave energy during these periods. Evaluation of the wave model results against observations from a buoy and satellites found that the spatial resolution of the wind model significantly affected the quality of the wave model results. Wind forcing from a 10-km grid produced higher skills for waves than winds from a

  6. Isolation and characterization of an antifungal protein from Bacillus licheniformis HS10.

    Science.gov (United States)

    Wang, Zhixin; Wang, Yunpeng; Zheng, Li; Yang, Xiaona; Liu, Hongxia; Guo, Jianhua

    2014-11-07

    Bacillus licheniformis HS10 is a good biocontrol agent against Pseudoperonospora cubensis which caused cucumber downy disease. To identify and characterize the antifungal proteins produced by B.licheniformis HS10, the proteins from HS10 were isolated by using 30-60% ammonium sulfate precipitation, and purified with column chromatography on DEAE Sepharose Fast Flow, RESOURCE Q and Sephadex G-75. And the SDS-PAGE and MALDI-TOF/TOF-MS analysis results demonstrated that the antifungal protein was a monomer with molecular weight of about 55 kDa, identified as carboxypeptidase. Our experiments also showed that the antifungal protein from B. licheniformis HS10 had significantly inhibition on eight different kinds of plant pathogenic fungi, and it was stable with good biological activity at as high as 100°C for 30 min and in pH value ranged from 6 to 10. The biological activity was negatively affected by protease K and 10mM metal cations except Ca(2+). Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Ocean Wave Simulation Based on Wind Field.

    Directory of Open Access Journals (Sweden)

    Zhongyi Li

    Full Text Available Ocean wave simulation has a wide range of applications in movies, video games and training systems. Wind force is the main energy resource for generating ocean waves, which are the result of the interaction between wind and the ocean surface. While numerous methods to handle simulating oceans and other fluid phenomena have undergone rapid development during the past years in the field of computer graphic, few of them consider to construct ocean surface height field from the perspective of wind force driving ocean waves. We introduce wind force to the construction of the ocean surface height field through applying wind field data and wind-driven wave particles. Continual and realistic ocean waves result from the overlap of wind-driven wave particles, and a strategy was proposed to control these discrete wave particles and simulate an endless ocean surface. The results showed that the new method is capable of obtaining a realistic ocean scene under the influence of wind fields at real time rates.

  8. Standardizing Scale Height Computation of Maven Ngims Neutral Data and Variations Between Exobase and Homeopause Scale Heights

    Science.gov (United States)

    Elrod, M. K.; Slipski, M.; Curry, S.; Williamson, H. N.; Benna, M.; Mahaffy, P. R.

    2017-12-01

    a jog or kink in the atmosphere in several atmospheric profiles slightly above the exobase indicating a change in the scale height between the super and supra- exobase temperatures. Waves are more prevalent on the night side and terminator sides making scale height fits more difficult. As a result we have added confidence level and error to the scale height fits to the lvl 3 product for reference.

  9. Hindcast of extreme sea states in North Atlantic extratropical storms

    Science.gov (United States)

    Ponce de León, Sonia; Guedes Soares, Carlos

    2015-02-01

    This study examines the variability of freak wave parameters around the eye of northern hemisphere extratropical cyclones. The data was obtained from a hindcast performed with the WAve Model (WAM) model forced by the wind fields of the Climate Forecast System Reanalysis (CFSR). The hindcast results were validated against the wave buoys and satellite altimetry data showing a good correlation. The variability of different wave parameters was assessed by applying the empirical orthogonal functions (EOF) technique on the hindcast data. From the EOF analysis, it can be concluded that the first empirical orthogonal function (V1) accounts for greater share of variability of significant wave height (Hs), peak period (Tp), directional spreading (SPR) and Benjamin-Feir index (BFI). The share of variance in V1 varies for cyclone and variable: for the 2nd storm and Hs V1 contains 96 % of variance while for the 3rd storm and BFI V1 accounts only for 26 % of variance. The spatial patterns of V1 show that the variables are distributed around the cyclones centres mainly in a lobular fashion.

  10. Evolution of offshore wind waves tracked by surface drifters with a point-positioning GPS sensor

    Science.gov (United States)

    Komatsu, K.

    2009-12-01

    Wind-generated waves have been recognized as one of the most important factors of the sea surface roughness which plays crucial roles in various air-sea interactions such as energy, momentum, heat and gas exchanges. At the same time, wind waves with extreme wave heights representatively called as freak or rogue waves have been a matter of great concern for many people involved in shipping, fishing, constracting, surfing and other marine activities, because such extreme waves frequently affect on the marine activities and sometimes cause serious disasters. Nevertheless, investigations of actual conditions for the evolution of wind waves in the offshore region are less and sparse in contrast to dense monitoring networks in the coastal regions because of difficulty of offshore observation with high accuracy. Recently accurate in situ observation of offshore wind waves is getting possible at low cost owing to a wave height and direction sensor developed by Harigae et al. (2004) by installing a point-positioning GPS receiver on a surface drifting buoy. The point-positioning GPS sensor can extract three dimensional movements of the buoy excited by ocean waves with minimizing effects of GPS point-positioning errors through the use of a high-pass filter. Two drifting buoys equipped with the GPS-based wave sensor charged by solar cells were drifted in the western North Pacific and one of them continued to observe wind waves during 16 months from Sep. 2007. The RMSE of the GPS-based wave sensor was less than 10cm in significant wave height and about 1s in significant wave period in comparison with other sensors, i.e. accelerometers installed on drifting buoys of Japan Meteorological Agency, ultrasonic sensors placed at the Hiratsuka observation station of the University of Tokyo and altimeter of the JASON-1. The GPS-based wave buoys enabled us to detect freak waves defined as waves whose height is more than twice the significant wave height. The observation conducted by the

  11. Wave Analysis Study for the Punta Catalina Jetty, Dominican Republic

    DEFF Research Database (Denmark)

    Røge, Mads Sønderstrup; Andersen, Thomas Lykke; Burcharth, Hans Falk

    This report deals with a two-dimensional test study to identify the largest significant wave height, the maximum wave height and the largest crest level along the Punta Catalina jetty in the Dominican Republic. The scale used for the model tests was 1:50. Unless otherwise specified all values given...

  12. Global well-posedness for the radial defocusing cubic wave equation on $R^3$ and for rough data

    Directory of Open Access Journals (Sweden)

    Tristan Roy

    2007-11-01

    Full Text Available We prove global well-posedness for the radial defocusing cubic wave equation $$displaylines{ partial_{tt} u - Delta u = -u^{3} cr u(0,x = u_{0}(x cr partial_{t} u(0,x = u_{1}(x }$$ with data $(u_0, u_1 in H^{s} imes H^{s-1}$, $1 > s >7/10$. The proof relies upon a Morawetz-Strauss-type inequality that allows us to control the growth of an almost conserved quantity.

  13. DHS HS-STEM Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Russell, Anna Christine [Sandia National Laboratories (SNL-CA), Livermore, CA (United States)

    2014-09-01

    Throughout my HS-STEM internship, I worked on two different projects with a systems analysis group at Sandia National Laboratories in Livermore, California (SNLCA). The first, and primary, project entailed building a conceptual model of health surveillance detection of a bioterror attack. The second project was much smaller in scope and looked at cost tradeoffs between volumetric and surface decontamination after the release of anthrax in a city. Both projects helped me to understand the challenges of planning for a bioterror attack and the importance of preparedness in the public health sector.

  14. Quantification of Wave Model Uncertainties Used for Probabilistic Reliability Assessments of Wave Energy Converters

    DEFF Research Database (Denmark)

    Ambühl, Simon; Kofoed, Jens Peter; Sørensen, John Dalsgaard

    2015-01-01

    Wave models used for site assessments are subjected to model uncertainties, which need to be quantified when using wave model results for probabilistic reliability assessments. This paper focuses on determination of wave model uncertainties. Four different wave models are considered, and validation...... data are collected from published scientific research. The bias and the root-mean-square error, as well as the scatter index, are considered for the significant wave height as well as the mean zero-crossing wave period. Based on an illustrative generic example, this paper presents how the quantified...... uncertainties can be implemented in probabilistic reliability assessments....

  15. Determination of Wave Model Uncertainties used for Probabilistic Reliability Assessments of Wave Energy Devices

    DEFF Research Database (Denmark)

    Ambühl, Simon; Kofoed, Jens Peter; Sørensen, John Dalsgaard

    2014-01-01

    Wave models used for site assessments are subject to model uncertainties, which need to be quantified when using wave model results for probabilistic reliability assessments. This paper focuses on determination of wave model uncertainties. Considered are four different wave models and validation...... data is collected from published scientific research. The bias, the root-mean-square error as well as the scatter index are considered for the significant wave height as well as the mean zero-crossing wave period. Based on an illustrative generic example it is shown how the estimated uncertainties can...... be implemented in probabilistic reliability assessments....

  16. Sexual Orientation, Objective Height, and Self-Reported Height.

    Science.gov (United States)

    Skorska, Malvina N; Bogaert, Anthony F

    2017-01-01

    Studies that have used mostly self-reported height have found that androphilic men and women are shorter than gynephilic men and women, respectively. This study examined whether an objective height difference exists or whether a psychosocial account (e.g., distortion of self-reports) may explain these putative height differences. A total of 863 participants, recruited at a Canadian university, the surrounding region, and through lesbian, gay, bisexual, and transgender (LGBT) events across Canada, self-reported their height and had their height measured. Androphilic men were shorter, on average, than gynephilic men. There was no objective height difference between gynephilic, ambiphilic, and androphilic women. Self-reported height, statistically controlling for objective height, was not related to sexual orientation. These findings are the first to show an objective height difference between androphilic and gynephilic men. Also, the findings suggest that previous studies using self-reported height found part of a true objective height difference between androphilic and gynephilic men. These findings have implications for existing biological theories of men's sexual orientation development.

  17. Wave attenuation in the Agulhas current

    CSIR Research Space (South Africa)

    Grundlingh, M

    1995-07-01

    Full Text Available The enlargement of surface wave height in the Agulhas Current, caused by waves propagating in the opposite direction to the current, is well known for its danger to large vessels traversing the Cape route. Occurrence characteristics...

  18. High-normal levels of hs-CRP predict the development of non-alcoholic fatty liver in healthy men.

    Directory of Open Access Journals (Sweden)

    Jieun Lee

    Full Text Available We performed a follow-up study to address whether high sensitivity C-reactive protein (hs-CRP levels within the normal range can predict the development of non-alcoholic fatty liver disease (NAFLD in healthy male subjects. Among15347 male workers between 30 and 59 years old who received annual health check-ups in 2002, a NAFLD-free cohort of 4,138 was followed through December 2009. Alcohol consumption was assessed with a questionnaire. At each visit, abdominal ultrasonography was performed to identify fatty liver disease. The COX proportional hazard model was used to evaluate the relationship between hs-CRP and incident NAFLD. During the follow-up period, 28.8% (1191 of 4138 of participants developed NAFLD. The hazard ratios of NAFLD were increased by hs-CRP categories within the normal range in the non-adjusted model and age-adjusted model. After adjusting for age, exercise, smoking, BMI, systolic BP, triglyceride, and fasting glucose, these incidences were only increased between the lowest and the highest hs-CRP categories. The risk for NAFLD increased as the hs-CRP level increased (p< 0.001. As the hs-CRP level increased within the healthy cohort, the risk of developing NAFLD increased. This trend remained true even if the hs-CRP level remained within the normal range. hs-CRP can be used as a predictor of NAFLD, as well as other obesity-associated diseases. Therefore, individuals with higher hs-CRP levels (even within the normal range may require appropriate follow-up and management to prevent NAFLD development.

  19. Intermittent fasting during Ramadan causes a transient increase in total, LDL, and HDL cholesterols and hs-CRP in ethnic obese adolescents.

    Science.gov (United States)

    Radhakishun, Nalini; Blokhuis, Charlotte; van Vliet, Mariska; von Rosenstiel, Ines; Weijer, Olivier; Heymans, Martijn; Beijnen, Jos; Brandjes, Dees; Diamant, Michaela

    2014-08-01

    The radical change of lifestyle during Ramadan fast has shown to affect cardiometabolic risk variables in adults. In youth, however, no studies are available. We aimed to evaluate the effect of Ramadan fast on Body Mass Index (BMI) and the cardiometabolic profile of obese adolescents. A prospective cohort study was conducted. We measured weight, height, body composition, blood pressure, heart rate, glucose, insulin, total cholesterol, low-density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL) cholesterol, triglycerides, and high sensitivity C-reactive protein (hs-CRP) levels before, during the last week of and at 6 weeks after Ramadan. Twenty-five obese adolescents were included. BMI and glucose metabolism did not change after Ramadan or at 6 week after cessation of Ramadan. At the end of Ramadan, a significant decrease in body fat percentage was observed, while significant increases in heart rate, total cholesterol, LDL cholesterol, HDL cholesterol, and hs-CRP were found (all P < 0.05). Six weeks after Ramadan, all parameters returned to baseline levels. In this sample of 25 ethnic obese adolescents transient cardiometabolic changes were observed during Ramadan fasting. Since most of these changes were reversible within 6 weeks, there seems no harm or benefit for obese adolescents to participate in Ramadan.

  20. On representations of Higher Spin symmetry algebras for mixed-symmetry HS fields on AdS-spaces. Lagrangian formulation

    International Nuclear Information System (INIS)

    Burdík, C; Reshetnyak, A

    2012-01-01

    We derive non-linear commutator HS symmetry algebra, which encode unitary irreducible representations of AdS group subject to Young tableaux Y(s 1 ,..., s k ) with κ ≥ 2 rows on d-dimensional anti-de-Sitter space. Auxiliary representations for specially deformed non-linear HS symmetry algebra in terms of generalized Verma module in order to additively convert a subsystem of second-class constraints in the HS symmetry algebra into one with first-class constraints are found explicitly for the case of HS fields for κ = 2 Young tableaux. The oscillator realization over Heisenberg algebra for obtained Verma module is constructed. The results generalize the method of auxiliary representations construction for symplectic sp(2κ) algebra used for mixed-symmetry HS fields on a flat spaces and can be extended on a case of arbitrary HS fields in AdS-space. Gauge-invariant unconstrained reducible Lagrangian formulation for free bosonic HS fields with generalized spin (s 1 , s 2 ) is derived.

  1. Wave Overtopping of a Barrier Beach

    Science.gov (United States)

    2009-09-01

    but can result in increased dune erosion along Scenic Road as occurred in 1993, 1997, and 2005 (James, 2005). Field data and observations for...factors are equal to 1. The equations for these run-up formulas are parameterized on significant wave height at the toe of the structure as measured in...3 exp C r SS RQ C D HgH γ ⎛ ⎞ = −⎜ ⎟ ⎝ ⎠ 2pξ > where the significant wave height at the toe of the structure, SH and pT are used. Again the

  2. Analysis of wave directional spreading using neural networks

    Digital Repository Service at National Institute of Oceanography (India)

    Deo, M.C.; Gondane, D.S.; SanilKumar, V.

    describes how a representative spreading parameter could be arrived at from easily available wave parameters such as significant wave height and average zero-cross wave period, using the technique of neural networks. It is shown that training of the network...

  3. Estimation of Ship Long-term Wave-induced Bending Moment using Closed-Form Expressions

    DEFF Research Database (Denmark)

    Jensen, Jørgen Juncher; Mansour, A. E.

    2002-01-01

    A semi-analytical approach is used to derive frequency response functions and standard deviations for the wave-induced bending moment amidships for mono-hull ships. The results are given as closed-form expressions and the required input information for the procedure is restricted to the main......-empirical closed-form expression for the skewness. The effect of whipping is included by assuming that whipping and wave-induced responses are conditionally independent given Hs. The procedure is simple and can be used to make quick estimates of the design wave bending moment at the conceptual design phase...

  4. Planetary wave-gravity wave interactions during mesospheric inversion layer events

    Science.gov (United States)

    Ramesh, K.; Sridharan, S.; Raghunath, K.; Vijaya Bhaskara Rao, S.; Bhavani Kumar, Y.

    2013-07-01

    lidar temperature observations over Gadanki (13.5°N, 79.2°E) show a few mesospheric inversion layer (MIL) events during 20-25 January 2007. The zonal mean removed SABER temperature shows warm anomalies around 50°E and 275°E indicating the presence of planetary wave of zonal wave number 2. The MIL amplitudes in SABER temperature averaged for 10°N-15°N and 70°E-90°E show a clear 2 day wave modulation during 20-28 January 2007. Prior to 20 January 2007, a strong 2day wave (zonal wave number 2) is observed in the height region of 80-90 km and it gets largely suppressed during 20-26 January 2007 as the condition for vertical propagation is not favorable, though it prevails at lower heights. The 10 day mean zonal wind over Tirunelveli (8.7°N, 77.8°E) shows deceleration of eastward winds indicating the westward drag due to wave dissipation. The nightly mean MF radar observed zonal winds show the presence of alternating eastward and westward winds during the period of 20-26 January 2007. The two dimensional spectrum of Rayleigh lidar temperature observations available for the nights of 20, 22, and 24 January 2007 shows the presence of gravity wave activity with periods 18 min, 38 min, 38 min, and vertical wavelengths 6.4 km, 4.0 km, 6.4 km respectively. From the dispersion relation of gravity waves, it is inferred that these waves are internal gravity waves rather than inertia gravity waves with the horizontal phase speeds of ~40 m/s, ~37 m/s, and ~50 m/s respectively. Assuming the gravity waves are eastward propagating waves, they get absorbed only in the eastward local wind fields of the planetary wave thereby causing turbulence and eddy diffusion which can be inferred from the estimation of large drag force due to the breaking of gravity wave leading to the formation of large amplitude inversion events in alternate nights. The present study shows that, the mesospheric temperature inversion is caused mainly due to the gravity wave breaking and the inversion

  5. Simulation of three-phase flow and lance height effect on the cavity shape

    Science.gov (United States)

    Dong, Kai; Zhu, Rong; Gao, Wei; Liu, Fu-hai

    2014-06-01

    A three-dimensional computational fluid dynamics (CFD) model was developed to simulate a 150-t top-blown converter. The effect of different lance heights on the cavity shape was investigated using the volume of fluid (VOF) method. Numerical simulation results can reflect the actual molten bath surface waves impinged by the supersonic oxygen jets. With increasing lance height, the cavity depth decreases, and the cavity area, varying like a parabola, increases and then decreases. The cavity area maximizes at the lance height of 1.3 m. Under the three different lance heights simulated in this study, all of the largest impact velocities at the molten bath surface are between 50 m/s and 100 m/s.

  6. Experimental modelling of wave amplification over irregular bathymetry for investigations of boulder transport by extreme wave events.

    Science.gov (United States)

    O'Boyle, Louise; Whittaker, Trevor; Cox, Ronadh; Elsäßer, Björn

    2017-04-01

    During the winter of 2013-2014 the west coast of Ireland was exposed to 6 storms over a period of 8 weeks with wind speeds equating to hurricane categories 3 and 4. During this period, the largest significant wave height recorded at the Marine Institute M6 wave buoy, approximately 300km from the site, was 13.6m (on 26th January 2014). However, this may not be the largest sea state of that winter, because the buoy stopped logging on 30th January and therefore failed to capture the full winter period. During the February 12th 2014 "Darwin" storm, the Kinsale Energy Gas Platform off Ireland's south coast measured a wave height of 25 m, which remains the highest wave measured off Ireland's coasts[1]. Following these storms, significant dislocation and transportation of boulders and megagravel was observed on the Aran Islands, Co. Galway at elevations of up to 25m above the high water mark and distances up to 220 m inland including numerous clasts with masses >50t, and at least one megagravel block weighing >500t [2]. Clast movements of this magnitude would not have been predicted from the measured wave heights. This highlights a significant gap in our understanding of the relationships between storms and the coastal environment: how are storm waves amplified and modified by interactions with bathymetry? To gain further understanding of wave amplification, especially over steep and irregular bathymetry, we have designed Froude-scaled wave tank experiments using the 3D coastal wave basin facility at Queen's University Belfast. The basin is 18m long by 16m wide with wave generation by means of a 12m wide bank of 24 top hinged, force feedback, sector carrier wave paddles at one end. The basin is equipped with gravel beaches to dissipate wave energy on the remaining three sides, capable of absorbing up to 99% of the incident wave energy, to prevent unwanted reflections. Representative bathymetry for the Aran Islands is modelled in the basin based on a high resolution

  7. Rational homoclinic solution and rogue wave solution for the ...

    Indian Academy of Sciences (India)

    –4]. Rogue waves were first observed in deep ocean [5]. A wave can be called a rogue wave when its height and steepness is much greater than the average crest, and appears from nowhere and disappears without a trace [6]. Rogue waves ...

  8. Dynamic and resuspension by waves and sedimentation pattern definition in low energy environments: guaíba lake (Brazil

    Directory of Open Access Journals (Sweden)

    João Luiz Nicolodi

    2013-03-01

    Full Text Available Little research has been undertaken into sediment dynamics in lakes, and most of it only analyses particular aspects such as the texture of the sediments. In this study, the characteristics of the wave field in Guaíba Lake are investigated. The parameters significant wave height (Hs, period (T and direction of wave propagation are examined together with their relation to the resuspension of sediments at the bottom. For this purpose, the mathematical model SWAN (Simulating Waves Nearshore has been validated and employed. The results pointed out that the highest waves modeled reached 0.55 m at a few points in the lake, particularly when winds were blowing from the S and SE quadrants with an intensity over 7 m.s-1. Generally speaking, waves follow wind intensity and direction patterns, and reach maximum height in about 1 to 2 hours after wind speed peaks. Whenever winds were stronger, waves took some 2 hours to reach 0.10 m. However, with weak to moderate winds, the waves took around 3 hours to achieve this value in significant wave height. In addition to speed and direction, wind regularity proved relevant in generating and propagating waves on Lake Guaíba. In conclusion the lake's sediment environments were mapped and classified as follows: 1 Depositional Environments (51% of the lake; 2 Transitional Environments (41%; and 3 Erosional or Non-Depositional Environments (8%. As a contribution to the region's environmental management, elements have been created relating to the concentration of suspended particulate matter.Pesquisas referentes à dinâmica sedimentar em lagos são escassas e a maioria trata da distribuição e textura dos sedimentos, sendo raras aquelas que fazem menção ao padrão de ondas e suas relações com a ressuspensão destes sedimentos e suas consequências. Este trabalho analisa as características das ondas incidentes no Lago Guaíba (Brasil por meio da utilização do SWAN (Simulating Waves Nearshore e suas rela

  9. Multipeakedness and groupiness of shallow water waves along Indian coast

    Digital Repository Service at National Institute of Oceanography (India)

    SanilKumar, V.; Anand, N.M.; AshokKumar, K.; Mandal, S.

    IM-.. .. . ..................................-;.. +++ -+t+++t+Mi-##+ ' .. ++~-* ..... + +t........ .. + .. .... .......... + ............................. _ ...·_-.a._IMIIIII....... I".".I .............Ht1t-+ .. l j ! I 0.0 l l I 1 l I i 0.0 0.1 0.2 0.3 5.0 0.0 6.0 I 0.2 0.4 0.6 0.8 1.0 5.0 5.0 5...- quencies fpl and fp2' The sequential correlation bet.ween suc cessive wave heights, r HH (RYE, 1974), between successive wave periods, r 1T and between wave height and wave period: r HT (GaDA, 1978) were evaluated as given below. Also the spec tral...

  10. Ig synthesis and class switching do not require the presence of the hs4 enhancer in the 3' IgH regulatory region.

    Science.gov (United States)

    Vincent-Fabert, Christelle; Truffinet, Véronique; Fiancette, Remi; Cogné, Nadine; Cogné, Michel; Denizot, Yves

    2009-06-01

    Several studies have reported that regulatory elements located 3' of the IgH locus (namely hs3a, hs1,2, hs3b, and hs4) might play a role during class switch recombination (CSR) and Ig synthesis. While individual deletion of hs3a or hs1,2 had no effect, pairwise deletion of hs3b (an inverted copy of hs3a) and hs4 markedly affected CSR and Ig expression. Among these two elements, hs4 was tentatively presented with the master role due to its unique status within the 3' regulatory region: distal position outside repeated regions, early activation in pre-B cells, strong activity throughout B cell ontogeny. To clarify its role, we generated mice with a clean deletion of the hs4 after replacement with a floxed neo(R) cassette. Surprisingly, and as for previous deletion of hs3a or hs1,2, deletion of hs4 did not affect either in vivo CSR or the secretion level of any Ig isotype. In vitro CSR and Ig secretion in response to LPS and cytokines was not affected either. The only noticeable effects of the hs4 deletion were a decrease in the number of B splenocytes and a decreased membrane IgM expression. In conclusion, while dispensable for CSR and Ig transcription in plasma cells, hs4 mostly appears to contribute to Ig transcription in resting B lymphocytes.

  11. Distribution of runup heights of the December 26, 2004 tsunami in the Indian Ocean

    Science.gov (United States)

    Choi, Byung Ho; Hong, Sung Jin; Pelinovsky, Efim

    2006-07-01

    A massive earthquake with magnitude 9.3 occurred on December 26, 2004 off the northern Sumatra generated huge tsunami waves affected many coastal countries in the Indian Ocean. A number of field surveys have been performed after this tsunami event; in particular, several surveys in the south/east coast of India, Andaman and Nicobar Islands, Sri Lanka, Sumatra, Malaysia, and Thailand have been organized by the Korean Society of Coastal and Ocean Engineers from January to August 2005. Spatial distribution of the tsunami runup is used to analyze the distribution function of the wave heights on different coasts. Theoretical interpretation of this distribution is associated with random coastal bathymetry and coastline led to the log-normal functions. Observed data also are in a very good agreement with log-normal distribution confirming the important role of the variable ocean bathymetry in the formation of the irregular wave height distribution along the coasts.

  12. A Stream Function Theory Based Calculation of Wave Kinematics for Very Steep Waves Using a Novel Non-linear Stretching Technique

    DEFF Research Database (Denmark)

    Stroescu, Ionut Emanuel; Sørensen, Lasse; Frigaard, Peter Bak

    2016-01-01

    A non-linear stretching method was implemented for stream function theory to solve wave kinematics for physical conditions close to breaking waves in shallow waters, with wave heights limited by the water depth. The non-linear stretching method proves itself robust, efficient and fast, showing good...

  13. High Temperature Monitoring the Height of Condensed Water in Steam Pipes

    Science.gov (United States)

    Bar-Cohen, Yoseph; Lih, Shyh-Shiuh; Badescu, Mircea; Bao, Xiaoqi; Sherrit, Stewart; Widholm, Scott; Ostlund, Patrick; Blosiu, Julian

    2011-01-01

    An in-service health monitoring system is needed for steam pipes to track through their wall the condensation of water. The system is required to measure the height of the condensed water inside the pipe while operating at temperatures that are as high as 250 deg. C. The system needs to be able to make real time measurements while accounting for the effects of cavitation and wavy water surface. For this purpose, ultrasonic wave in pulse-echo configuration was used and reflected signals were acquired and auto-correlated to remove noise from the data and determine the water height. Transmitting and receiving the waves is done by piezoelectric transducers having Curie temperature that is significantly higher than 250 deg. C. Measurements were made at temperatures as high as 250 deg. C and have shown the feasibility of the test method. This manuscript reports the results of this feasibility study.

  14. Revised photometric elements of QY Aql, V388 Cyg and HS Her

    International Nuclear Information System (INIS)

    Giuricin, G.; Mardirossian, F.

    1981-01-01

    Using Wood's model we have reanalyzed the light curves of the eclipsing binaries QY Aql, V388 Cyg, and HS Her. For QY Aql and HS Her our photometric solutions substantially confirm previous results, thus respectively supporting an sd-d classification and a main sequence detached view. On the other hand, significantly different photometric elements have been derived for V388 Cyg, which is likely to be an evolved contact binary. (orig.)

  15. Propagation of stationary Rossby waves in the Martian lower atmosphere

    Science.gov (United States)

    Ghosh, Priyanka; Thokuluwa, Ramkumar

    The Martian lower atmospheric (-1.5 km to 29.3 km) temperature, measured by radio occultation technique during the Mars Global Surveyor (MGS) mission launched by US in November 1996, at the Northern winter hemispheric latitude of about 63(°) N clearly shows a statistically significant (above 95 percent confidential level white noise) and strong 3.5-day oscillation during 1-10 January 2006. This strong signal occurs in the longitudinal sectors of 0-30(°) E and 190-230(°) E but statistically insignificant in almost all the other longitudes. This 180 degree separation between the two peaks of occurrence of strong 3.5 day oscillation indicates that this may be associated with zonal wave number 2 structure global scale wave. At the lowest height of -1.5 km, the power observed in the longitude of 0-30(°) E is 50 K (2) and it increased gradually to the maximum power of 130 K (2) at the height of 0.8 - 1.7 km. Above this height, the power decreased monotonously and gradually to insignificant level at the height of 3.7 km (20 K (2) ). This gradual decrease of power above the height of 1.7 km indicates that radiative damping (infra red cooling due to large abundance of CO _{2} molecules and dust particles) would have played an important role in the dissipation of waves. The height and longitudinal profiles of phase of the 3.5-day wave indicate that this wave is a vertically standing and eastward propagating planetary wave respectively. Since the statistically significant spectral amplitude occurs near the high topography structures, it seems that the wave is generated by flows over the topography. In the Northern winter, it is possible that the large gradient of temperature between the low and high latitudes would lead to flow of winds from the tropical to polar latitudes. Due to the Coriolis effect, this flow would in turn move towards the right and incite wave generation when the air flows over the high topographic structures. This lead to speculate that the observed 3

  16. Prediction of HS Soderberg plant PAH emissions from a laboratory evaluation of a pitch

    Energy Technology Data Exchange (ETDEWEB)

    Castonguay, L.; Mirtchi, A. A.; Proulx, A. L.; Savard, G.; Simard, E.; Steward, N.; Tremblay, C. [Alcan International Ltd., Arvida Research and Development Centre, Jonquiere, PQ (Canada)

    1998-12-31

    The presence of certain polycyclic aromatic hydrocarbons (PAHs) in coal tar pitch has been identified as a possible limit to the long-term viability of horizontal stud (HS) Soderberg technology, a technology of importance in the aluminum industry. This paper presents the results of a comparative study of pitch PAH content and HS Soderberg cell emissions. Laboratory results are compared with plant emissions for two regular and low PAH pitches with the same softening points. The results indicate the existence of a correlation between pitch PAH content and cell emission, which is valid for regular tar pitches, low tar pitches, as well as for hybrid pitches. These findings make it possible to predict the quantity and distribution of HS Soderberg cell PAH emissions from the analysis of PAHs in the pitch. The results also justify the conclusion that the emission of genotoxic compounds from pitch in the HS Soderberg technology can be decreased by using a pitch with low PAH content. 4 refs., 5 tabs., 5 figs.

  17. Observations and estimates of wave-driven water level extremes at the Marshall Islands

    Science.gov (United States)

    Merrifield, M. A.; Becker, J. M.; Ford, M.; Yao, Y.

    2014-10-01

    Wave-driven extreme water levels are examined for coastlines protected by fringing reefs using field observations obtained in the Republic of the Marshall Islands. The 2% exceedence water level near the shoreline due to waves is estimated empirically for the study sites from breaking wave height at the outer reef and by combining separate contributions from setup, sea and swell, and infragravity waves, which are estimated based on breaking wave height and water level over the reef flat. Although each component exhibits a tidal dependence, they sum to yield a 2% exceedence level that does not. A hindcast based on the breaking wave height parameterization is used to assess factors leading to flooding at Roi-Namur caused by an energetic swell event during December 2008. Extreme water levels similar to December 2008 are projected to increase significantly with rising sea level as more wave and tide events combine to exceed inundation threshold levels.

  18. A3-Coupling catalyzed by robust Au nanoparticles covalently bonded to HS-functionalized cellulose nanocrystalline films

    Directory of Open Access Journals (Sweden)

    Jian-Lin Huang

    2013-07-01

    Full Text Available We decorated HS-functionalized cellulose nanocrystallite (CNC films with monodisperse Au nanoparticles (AuNPs to form a novel nanocomposite catalyst AuNPs@HS-CNC. The uniform, fine AuNPs were made by the reduction of HAuCl4 solution with thiol (HS- group-functionalized CNC films. The AuNPs@HS-CNC nanocomposites were examined by X-ray photoelectron spectroscopy (XPS, TEM, ATR-IR and solid-state NMR. Characterizations suggested that the size of the AuNPs was about 2–3 nm and they were evenly distributed onto the surface of CNC films. Furthermore, the unique nanocomposite Au@HS-CNC catalyst displayed high catalytic efficiency in promoting three-component coupling of an aldehyde, an alkyne, and an amine (A3-coupling either in water or without solvent. Most importantly, the catalyst could be used repetitively more than 11 times without significant deactivation. Our strategy also promotes the use of naturally renewable cellulose to prepare reusable nanocomposite catalysts for organic synthesis.

  19. Fatty acid methyl esters and Solutol HS 15 confer neuroprotection after focal and global cerebral ischemia.

    Science.gov (United States)

    Lin, Hung Wen; Saul, Isabel; Gresia, Victoria L; Neumann, Jake T; Dave, Kunjan R; Perez-Pinzon, Miguel A

    2014-02-01

    We previously showed that palmitic acid methyl ester (PAME) and stearic acid methyl ester (SAME) are simultaneously released from the sympathetic ganglion and PAME possesses potent vasodilatory properties which may be important in cerebral ischemia. Since PAME is a potent vasodilator simultaneously released with SAME, our hypothesis was that PAME/SAME confers neuroprotection in rat models of focal/global cerebral ischemia. We also examined the neuroprotective properties of Solutol HS15, a clinically approved excipient because it possesses similar fatty acid compositions as PAME/SAME. Asphyxial cardiac arrest (ACA, 6 min) was performed 30 min after PAME/SAME treatment (0.02 mg/kg, IV). Solutol HS15 (2 ml/kg, IP) was injected chronically for 14 days (once daily). Histopathology of hippocampal CA1 neurons was assessed 7 days after ACA. For focal ischemia experiments, PAME, SAME, or Solutol HS15 was administered following reperfusion after 2 h of middle cerebral artery occlusion (MCAO). 2,3,5-Triphenyltetrazolium staining of the brain was performed 24 h after MCAO and the infarct volume was quantified. Following ACA, the number of surviving hippocampal neurons was enhanced by PAME-treated (68%), SAME-treated (69%), and Solutol-treated HS15 (68%) rats as compared to ACA only-treated groups. Infarct volume was decreased by PAME (83%), SAME (68%), and Solutol HS15 (78%) as compared to saline (vehicle) in MCAO-treated animals. PAME, SAME, and Solutol HS15 provide robust neuroprotection in both paradigms of ischemia. This may prove therapeutically beneficial since Solutol HS15 is already administered as a solublizing agent to patients. With proper timing and dosage, administration of Solutol HS15 and PAME/SAME can be an effective therapy against cerebral ischemia.

  20. Fear of heights and visual height intolerance.

    Science.gov (United States)

    Brandt, Thomas; Huppert, Doreen

    2014-02-01

    The aim of this review is, first, to cover the different aspects of visual height intolerance such as historical descriptions, definition of terms, phenomenology of the condition, neurophysiological control of gaze, stance and locomotion, and therapy, and, second, to identify warranted epidemiological and experimental studies. Vivid descriptions of fear of heights can be found in ancient texts from the Greek, Roman, and Chinese classics. The life-time prevalence of visual height intolerance is as high as 28% in the general population, and about 50% of those who are susceptible report an impact on quality of life. When exposed to heights, visual exploration by eye and head movements is restricted, and the velocity of locomotion is reduced. Therapy for fear of heights is dominated by the behavioral techniques applied during real or virtual reality exposure. Their efficacy might be facilitated by the administration of D-cycloserine or glucocorticoids. Visual height intolerance has a considerable impact on daily life and interpersonal interactions. It is much more frequent than fear of heights, which is defined as an environmental subtype of a specific phobia. There is certainly a continuum stretching from acrophobia to a less-pronounced visual height intolerance, to which the categorical distinction of a specific phobia does not apply.

  1. Role of beach morphology in wave overtopping hazard assessment

    Science.gov (United States)

    Phillips, Benjamin; Brown, Jennifer; Bidlot, Jean-Raymond; Plater, Andrew

    2017-04-01

    Understanding the role of beach morphology in controlling wave overtopping volume will further minimise uncertainties in flood risk assessments at coastal locations defended by engineered structures worldwide. XBeach is used to model wave overtopping volume for a 1:200 yr joint probability distribution of waves and water levels with measured, pre- and post-storm beach profiles. The simulation with measured bathymetry is repeated with and without morphological evolution enabled during the modelled storm event. This research assesses the role of morphology in controlling wave overtopping volumes for hazardous events that meet the typical design level of coastal defence structures. Results show disabling storm-driven morphology under-represents modelled wave overtopping volumes by up to 39% under high Hs conditions, and has a greater impact on the wave overtopping rate than the variability applied within the boundary conditions due to the range of wave-water level combinations that meet the 1:200 yr joint probability criterion. Accounting for morphology in flood modelling is therefore critical for accurately predicting wave overtopping volumes and the resulting flood hazard and to assess economic losses.

  2. Tsunami Wave Run-up on a Vertical Wall in Tidal Environment

    Science.gov (United States)

    Didenkulova, Ira; Pelinovsky, Efim

    2018-04-01

    We solve analytically a nonlinear problem of shallow water theory for the tsunami wave run-up on a vertical wall in tidal environment. Shown that the tide can be considered static in the process of tsunami wave run-up. In this approximation, it is possible to obtain the exact solution for the run-up height as a function of the incident wave height. This allows us to investigate the tide influence on the run-up characteristics.

  3. General characteristics of long waves around the South African Coast

    CSIR Research Space (South Africa)

    Rossouw, M

    2013-09-01

    Full Text Available Long-period waves are almost invisible waves due to the long wave-lengths of several hundreds of metres and heights of only decimetres. The effect of these long waves can, however, be devastating in the form of harbour basin oscillations...

  4. Significant wave height data from bottom-mounted pressure sensors at three sites in progressively deeper locations along the Outer Reef in Kailua Bay, Oahu, Hawaii from 28 September 2000 to 06 October 2000 (NODC Accession 0000347)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Wave height and other data were collected at fixed platforms in the Coastal Waters of Hawaii and Northeast Pacific Ocean from September 28, 2000 to October 06, 2000....

  5. Modified application of HS-SPME for quality evaluation of essential oil plant materials.

    Science.gov (United States)

    Dawidowicz, Andrzej L; Szewczyk, Joanna; Dybowski, Michal P

    2016-01-01

    The main limitation in the standard application of head space analysis employing solid phase microextraction (HS-SPME) for the evaluation of plants as sources of essential oils (EOs) are different quantitative relations of EO components from those obtained by direct analysis of EO which was got in the steam distillation (SD) process from the same plant (EO/SD). The results presented in the paper for thyme, mint, sage, basil, savory, and marjoram prove that the quantitative relations of EO components established by HS-SPME procedure and direct analysis of EO/SD are similar when the plant material in the HS-SPME process is replaced by its suspension in oil of the same physicochemical character as that of SPME fiber coating. The observed differences in the thyme EO composition estimated by both procedures are insignificant (F(exp)HS-SPME procedure proposed in this paper substantially shortens the evaluation time of plant material quality and thus may improve the efficiency of analytical laboratories. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Experimental evaluation of the effect of wave focusing walls on the performance of the Sea-wave Slot-cone Generator

    International Nuclear Information System (INIS)

    Oliveira, P.; Taveira-Pinto, F.; Morais, T.; Rosa-Santos, P.

    2016-01-01

    Highlights: • The application of the Sea-wave Slot-cone Generator (SSG) in breakwaters is promising. • The use of wave focusing walls (WFW) improves the performance of the SSG technology. • The WFW concentrate the incident wave energy and increase the overtopping flow rates. • The design of new SSG devices should take into account the eventual use of WFW. • The use of WFW increased the annual energy production approximately to the double. - Abstract: The Sea-wave Slot-cone Generator (SSG) is a multi-level overtopping based wave energy converter that can be installed either nearshore or offshore. The installation in harbor breakwaters and in the shoreline presents several advantages despite the usual exposure to smaller waves than at offshore locations. This work analyzes the effect of wave focusing walls (i.e., wave concentrators) on the performance of isolated SSG units using a physical model built on a geometric scale of 1/40. Seven configurations were defined by changing the opening angle and the crest level of those elements. The use of wave concentrators proved to be advantageous since a wider wave front is captured and the run-up and overtopping phenomena are enhanced on the SSG ramp owing to the wave energy concentration (walls tapering effect). In fact, the total mean power captured increased for all SSG configurations with concentrators in comparison to the base configuration (without concentrators), regardless of the sea state considered. In terms of hydraulic performance, the gain associated to the use of wave concentrators depends on the characteristics of incident waves, being higher for the smaller significant wave heights and the shorter peak wave periods. The hydraulic efficiency, defined as the ratio between the total mean power captured per meter of SSG width and the wave power per meter width of the incident waves, increases with the significant wave height and reduces with the peak wave period in all tested SSG configurations. In

  7. Fibroblast Growth Factor 21 (FGF21, Free Fatty Acid (FFA, High Sensitivity C-reactive Protein (hsCRP and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR Among Indonesian Obese Non-Diabetic Males

    Directory of Open Access Journals (Sweden)

    Yani Lina

    2009-12-01

    Full Text Available BACKGROUND: Fibroblast growth factor-21 (FGF21 is known as an important endocrine and paracrine regulator of metabolic homeostasis. Recent studies have shown that FGF21 attenuates lipolysis in human adipocytes, which is suggested as a FGF21's mechanism as anti-hyperlipidemia, anti-hyperglycemia and anti-obesity. The aim of this study was to measure the correlation between FGF21, FFA, hsCRP and HOMA-IR among Indonesian obese non diabetic males. METHODS: The study was observational with cross sectional design. The analysis was done in 137 subjects aged 30-60 years with non diabetic abdominal obesity. We measured the biochemical markers FGF21, FFA, hsCRP, fasting insulin and fasting glucose. We also measured weight, height, waist circumrefence (WC, creatinine, serum glutamin oxaloacetic transaminase (SGOT, and serum glutamic pyruvic transaminase (SGPT, systolic blood pressure (SBP and diastolic blood pressure (DBP. Correlation between markers was measured using Pearson and Spearman's analysis. RESULTS: There were significant positive correlations between FGF21-HOMA-IR (r=0.314, p=0.000; FGF21-WC (r=0.173, p=0.043; FFA=hsCRP r=0.270, p=0.001; and WC-HOMA-IR (r=0.279, p=0.001. There was significant negative correlation between FGF21-FFA (r=-0.038, p=0.657 and FGF21-hsCRP (r=-0.061, p=0.482. CONCLUSIONS: In this study we found that although there was no significant correlation, FGF21 might act as an anti-lipolytic and anti-inflammation agent among Indonesian obese non-diabetic males. Our findings agree with results of previous studies that the positive correlation between FGF21-WC and FGF21-HOMA-IR might occur as a compensatory mechanism or resistance to FGF21 in obesity. KEYWORDS: obesity, FGF21, FFA, hsCRP, HOMA-IR.

  8. Serum Pentraxin 3 and hs-CRP Levels in Children with Severe Pulmonary Hypertension

    Directory of Open Access Journals (Sweden)

    Cemşit Karakurt

    2014-09-01

    Full Text Available Background: Pulmonary arterial hypertension secondary to untreated left-to-right shunt defects leads to increased pulmonary blood flow, endothelial dysfunction, increased pulmonary vascular resistance, vascular remodelling, neointimal and plexiform lesions. Some recent studies have shown that inflammation has an important role in the pathophysiology of pulmonary arterial hypertension. Aims: The aim of this study is to evaluate serum pentraxin 3 and high sensitive (hs-C reactive protein (hs-CRP levels in children with severe pulmonary arterial hypertension (PAH secondary to untreated congenital heart defects and evaluate the role of inflammation in pulmonary hypertension. Study Design: Cross sectional study. Methods: After ethics committee approval and receiving consent from parents, there were 31 children were selected for the study with severe PAH, mostly with a left-to-right shunt, who had been assessed by cardiac catheterisation and were taking specific pulmonary vasodilators. The control group consisted of 39 age and gender matched healthy children. After recording data about all the patients including age, gender, weight, haemodynamic studies and vasodilator testing, a physical examination was done for all subjects. Blood was taken from patients and the control group using peripheral veins to analyse serum Pentraxin 3, N-terminal pro-Brain Natriuretic Peptide (NT-ProBNP and hs-CRP levels. Serum Pentraxin-3 levels were measured by enzyme linked immunosorbent assay (ELISA and expressed as ng/mL. Serum hs-CRP levels were measured with an immunonephelometric method and expressed as mg/dL. The serum concentration of NT-proBNP was determined by a chemiluminescent immunumetric assay and expressed as pg/mL. Results: Serum Pentraxin- 3 levels were determined to be 1.28±2.12 (0.12-11.43 in the PAH group (group 1 and 0.40±0.72 (0.07-3.45 in group 2. There was a statistically significant difference between the two groups (p<0.01. Serum hs-CRP levels

  9. Wave-induced current considering wave-tide interaction in Haeundae

    Science.gov (United States)

    Lim, Hak Soo

    2017-04-01

    The Haeundae, located at the south eastern end of the Korean Peninsula, is a famous beach, which has an approximately 1.6 km long and 70 m wide coastline. The beach has been repeatedly eroded by the swell waves caused by typhoons in summer and high waves originating in the East Sea in winter. The Korean government conducted beach restoration projects including beach nourishment (620,000 m3) and construction of two submerged breakwaters near both ends of the beach. To prevent the beach erosion and to support the beach restoration project, the Korean government initiated a R&D project, the development of coastal erosion control technology since 2013. As a part of the project, we have been measuring waves and currents at a water depth of 22 m, 1.8 km away from the beach using an acoustic wave and current meter (AWAC) continuously for more than three years; we have also measured waves and currents intensively near the surf-zone in summer and winter. In this study, a numerical simulation using a wave and current coupled model (ROMS-SWAN) was conducted for determining the wave-induced current considering seasonal swell waves (Hs : 2.5 m, Tp: 12 s) and for better understanding of the coastal process near the surf-zone in Haeundae. By comparing the measured and simulated results, we found that cross-shore current during summer is mainly caused by the eddy produced by the wave-induced current near the beach, which in turn, is generated by the strong waves coming from the SSW and S directions. During other seasons, longshore wave-induced current is produced by the swell waves coming from the E and ESE directions. The longshore current heading west toward Dong-Back Island, west end of the beach, during all the seasons and eddy current toward Mipo-Port, east end of the beach, in summer which is well matched with the observed residual current. The wave-induced current with long-term measurement data is incorporated in simulation of sediment transport modeling for developing

  10. Wave Transformation over a Fringing Coral Reef and the Importance of Low-Frequency Waves and Offshore Water Levels to Runup and Island Overtopping

    Science.gov (United States)

    Cheriton, O. M.; Storlazzi, C. D.; Rosenberger, K. J.

    2016-02-01

    Low-lying, reef-fringed islands are susceptible to sea-level rise and often subjected to overwash and flooding during large wave events. To quantify wave dynamics and wave-driven water levels on fringing coral reefs, wave gauges and a current meter were deployed for 5 months across two shore-normal transects on Roi-Namur, an atoll island in the Republic of the Marshall Islands. These observations captured two large wave events that had maximum wave heights greater than 6 m and peak periods of 16 s over the fore reef. The larger event coincided with a peak spring tide, leading to energetic, highly-skewed infragravity (0.04-0.004 Hz) and very low frequency (0.004-0.001 Hz) waves at the shoreline, which reached heights of 1.0 and 0.7 m, respectively. Water surface elevations, combined with wave runup, exceeded 3.7 m at the innermost reef flat adjacent to the toe of the beach, resulting in flooding of inland areas. This overwash occurred during a 3-hr time window that coincided with high tide and maximum low-frequency reef flat wave heights. The relatively low-relief characteristics of this narrow reef flat may further drive shoreline amplification of low-frequency waves due to resonance modes. These results demonstrate how the coupling of high offshore water levels with low-frequency reef flat wave energetics can lead to large impacts along atoll and fringing reef-lined shorelines, such as island overwash. These observations lend support to the hypothesis that predicted higher sea levels will lead to more frequent occurrences of both extreme shoreline runup and island overwash, threatening the sustainability of these islands.

  11. Statistical investigation of expected wave energy and its reliability

    International Nuclear Information System (INIS)

    Ozger, M.; Altunkaynak, A.; Sen, Z.

    2004-01-01

    The statistical behavior of wave energy at a single site is derived by considering simultaneous variations in the period and wave height. In this paper, the general wave power formulation is derived by using the theory of perturbation. This method leads to a general formulation of the wave power expectation and other statistical parameter expressions, such as standard deviation and coefficient of variation. The statistical parameters, namely the mean value and variance of wave energy, are found in terms of the simple statistical parameters of period, significant wave height and zero up-crossing period. The elegance of these parameters is that they are distribution free. These parameters provide a means for defining the wave energy distribution function by employing the Chebyschev's inequality. Subsequently, an approximate probability distribution function of the wave energy is also derived for assessment of risk and reliability associated with wave energy. Necessary simple charts are given for risk and reliability assessments. Two procedures are presented for such assessments in wave energy calculations and the applications of these procedures are provided for wave energy potential assessment in the regions of the Pacific Ocean off the west coast of U.S. (author)

  12. Statistical investigation of expected wave energy and its reliability

    International Nuclear Information System (INIS)

    Oezger, Mehmet; Altunkaynak, Abduesselam; Sen, Zekai

    2004-01-01

    The statistical behavior of wave energy at a single site is derived by considering simultaneous variations in the period and wave height. In this paper, the general wave power formulation is derived by using the theory of perturbation. This method leads to a general formulation of the wave power expectation and other statistical parameter expressions, such as standard deviation and coefficient of variation. The statistical parameters, namely the mean value and variance of wave energy, are found in terms of the simple statistical parameters of period, significant wave height and zero up-crossing period. The elegance of these parameters is that they are distribution free. These parameters provide a means for defining the wave energy distribution function by employing the Chebyschev's inequality. Subsequently, an approximate probability distribution function of the wave energy is also derived for assessment of risk and reliability associated with wave energy. Necessary simple charts are given for risk and reliability assessments. Two procedures are presented for such assessments in wave energy calculations and the applications of these procedures are provided for wave energy potential assessment in the regions of the Pacific Ocean off the west coast of U.S

  13. The Role of the Media in South African Construction Health and Safety (H&S

    Directory of Open Access Journals (Sweden)

    John Smallwood

    2012-11-01

    Full Text Available A large number of fatalities and injuries occur in the South African construction industry. Traditionally, the print media have dedicated editorial, published news, articles and letters, and have exposed abusive or non-conforming conditions and practices in terms of H&S. Literature also indicates that the print media can influence and has an impact on H&S.Given the level of fatalities and injuries and the potential role of the print media, a postal survey was conducted among editors of construction and related magazines. Findings indicate that: the print media do contribute to and play a role in construction H&S; industry has the capacity and needs to promote H&S on a wider basis; there is a need to improve construction H&S; to a degree, editors are aware of what constitutes unsafe acts and unsafe conditions, and the print media can play an increased role through the review of articles, advertisements, advertorial, editorial and phototgraphs to prevent the depiction of unhealthy and unsafe practices and conditions

  14. Extreme Waves in Svåheia SSG Location

    DEFF Research Database (Denmark)

    Margheritini, Lucia; Kofoed, Jens Peter

    The present report is the written documentation of the work carried under a consultancy project agreement between WaveEnergy AS and Aalborg University (AAU). The purpose of the study is to define maximum wave heights and related waves loading acting on the SSG in Svaheia, Norway and to provide th...

  15. A study of acoustic halos in active region NOAA 11330 using multi-height SDO observations

    Science.gov (United States)

    Tripathy, S. C.; Jain, K.; Kholikov, S.; Hill, F.; Rajaguru, S. P.; Cally, P. S.

    2018-01-01

    We analyze data from the Helioseismic Magnetic Imager (HMI) and the Atmospheric Imaging Assembly (AIA) instruments on board the Solar Dynamics Observatory (SDO) to characterize the spatio-temporal acoustic power distribution in active regions as a function of the height in the solar atmosphere. For this, we use Doppler velocity and continuum intensity observed using the magnetically sensitive line at 6173 Å as well as intensity at 1600 Å and 1700 Å. We focus on the power enhancements seen around AR 11330 as a function of wave frequency, magnetic field strength, field inclination and observation height. We find that acoustic halos occur above the acoustic cutoff frequency and extends up to 10 mHz in HMI Doppler and AIA 1700 Å observations. Halos are also found to be strong functions of magnetic field and their inclination angle. We further calculate and examine the spatially averaged relative phases and cross-coherence spectra and find different wave characteristics at different heights.

  16. Simulations of short-crested harbour waves with variational Boussinesq modelling

    NARCIS (Netherlands)

    Adytia, D.

    2014-01-01

    Waves propagating from the deep ocean to the coast show large changes in wave height, wave length and direction. The challenge to simulate the essential wave characteristics is in particular to model the speed and nonlinear interaction correctly. All these physical phenomena are present, but hidden,

  17. Mechanistic study of solubility enhancement of nifedipine using vitamin E TPGS or solutol HS-15.

    Science.gov (United States)

    Rajebahadur, Minal; Zia, Hossein; Nues, Anthony; Lee, Chong

    2006-01-01

    The objective of our study was to find mechanisms responsible for solubility enhancement of nifedipine in solid dispersions of vitamin E TPGS and/or solutol HS-15. Solid dispersions of nifedipine with selected polymers such as vitamin E TPGS, solutol HS-15, PEG(1,000), and lipocol C-10 of varying drug/polymer ratios were prepared by a fusion method. The solubility enhancement was found to be in the order of vitamin E TPGS > solutol HS-15 > lipocol C-10 > PEG(1,000). Lipocol C-10, with a similar hydrophilic-lipophilic value as vitamin E TPGS, showed a comparable retained solubility enhancement during saturation solubility studies but had lower dissolution profile. Overall, vitamin E TPGS showed the best solubility and dissolution performance, while solutol HS-15 and lipocol C-10 demonstrated moderate solubility enhancements. Solid dispersions of vitamin E TPGS as prepared by microfluidization technique initially showed slightly higher solubility compared with samples prepared by fusion method, but eventually it became the same as the study progressed. However, solid dispersion of solutol HS-15 as prepared by microfluidization demonstrated a significant, sustained increased in solubility over its sample when prepared by fusion method. Based on these results, we concluded that enhanced solubility using vitamin E TPGS and solutol HS-15 resulted from a partial conversion of crystalline drug to the amorphous form, increase in wettability of the drug by water soluble polymers, better separation of drug particles, micellar solubilization of drug by high concentrations of surfactant polymers, and interaction between polymer and drug at the molecular level.

  18. Observation and parametrization of wave attenuation through the MIZ

    Science.gov (United States)

    Ardhuin, F.; Stopa, J.; Dumont, D.; Sévigny, C.; Collard, F.; Boutin, G.

    2016-02-01

    Swell evolution from the open ocean into sea ice is poorly understood, in particular the amplitude attenuation expected from scattering and dissipation. New synthetic aperture radar (SAR) data from Sentinel-1 wave mode reveal intriguing patterns of bright oscillating lines shaped like instant noodles. We investigate cases in which the oscillations are in the azimuth direction, around a straight line in the range direction. This observation is interpreted as the distortion by the SAR processing of crests from a first swell, due to the presence of a second swell. Since deviations from a straight line should be proportional to the orbital velocity towards the satellite, swell height can be estimated. The intensity of the backscatter modulation with a single swell can also be used to retrieve swell height as it is found that the constructive velocity bunching is very sensitive to wave height. Using a novel algorithm to invert the wave directional spectrum, we investigate several cases of attenuation in the Arctic and southern ocean. On this basis we have adjusted an empirical wave-ice dissipation source term in the WAVEWATCH III model.

  19. Directional wave measurements off Navinal, Gulf of Kachchh, India

    Digital Repository Service at National Institute of Oceanography (India)

    Vethamony, P.; KrishnaKumar, V.; Suryanarayana, A.; Antony, M.K.; Swamy, G.N.

    .54 m respectively. Though large wave heights of the order of 3 to 4m exist elsewhere along the west coast of India during these seasons, Navinal seems to be a less wave active zone because of its geographical location. Maximum wave energy is centred...

  20. Modification of the Armijo line search to satisfy the convergence properties of HS method

    Directory of Open Access Journals (Sweden)

    Mohammed Belloufi

    2013-07-01

    Full Text Available The Hestenes-Stiefel (HS conjugate gradient algorithm is a useful tool of unconstrainednumerical optimization, which has good numerical performance but no global convergence result under traditional line searches. This paper proposes a line search technique that guarantee the globalconvergence of the Hestenes-Stiefel (HS conjugate gradient method. Numerical tests are presented tovalidate the different approaches.

  1. Characteristics of sediment resuspension in Lake Taihu, China: A wave flume study

    Science.gov (United States)

    Ding, Yanqing; Sun, Limin; Qin, Boqiang; Wu, Tingfeng; Shen, Xia; Wang, Yongping

    2018-06-01

    Lake Taihu is a typical shallow lake which frequently happens sediment resuspension induced by wind-induced waves. The experiments are carried on to simulate the wave disturbance processes in wave flume by setting a series of wave periods (1.2 s, 1.5 s, 1.8 s) and wave heights (2 cm, 10 cm). It aims to analyze the characteristics of sediment resuspension and the mechanisms of nutrients release and to evaluate the effects of sediment dredging on sediment resuspension and nutrients release in Lake Taihu. The results show that wave shear stress during 2 cm and 10 cm wave height processes ranges 0.018-0.023 N/m2 and 0.221-0.307 N/m2, respectively. Wave shear stress has no significant differences between wave periods. Wave height has much more effects on sediment resuspension. Wave height of 2 cm could induce total suspended solids (TSS) reaching up to 5.21 g/m2 and resuspension flux of sediment (M) up to 1.74 g/m2. TSS sharply increases to 30.33-52.41 g/m2 and M reached up to 48.94 g/m2 when wave height reaches to 10 cm. The disturbance depth under different sediment bulk weights ranges from 0.089 to 0.161 mm. Variation of suspended solids in 3 layers (1 cm, 5 cm, 20 cm above sediment interface) has no significant differences. Organic matter, TN and TP have positive relationship with SS. Organic matter is only accounted for 5.7%-7.3% of SS. The experiments under different sediment bulk densities (1.34 g/cm3, 1.47 g/cm3 and 1.59 g/cm3) find that TSS and M fall by 44.2% and 39.8% with sediment bulk density increasing, respectively. Total TN, DTN, TP and DTP decrease by 24.3%-33.6%. It indicates that sediment dredging could effectively reduce SS concentration and nutrient levels in water column. The researches provide a theoretical basis for sediment dredging to control the shore zone of Lake Taihu for lake management.

  2. Water level effects on breaking wave setup for Pacific Island fringing reefs

    Science.gov (United States)

    Becker, J. M.; Merrifield, M. A.; Ford, M.

    2014-02-01

    The effects of water level variations on breaking wave setup over fringing reefs are assessed using field measurements obtained at three study sites in the Republic of the Marshall Islands and the Mariana Islands in the western tropical Pacific Ocean. At each site, reef flat setup varies over the tidal range with weaker setup at high tide and stronger setup at low tide for a given incident wave height. The observed water level dependence is interpreted in the context of radiation stress gradients specified by an idealized point break model generalized for nonnormally incident waves. The tidally varying setup is due in part to depth-limited wave heights on the reef flat, as anticipated from previous reef studies, but also to tidally dependent breaking on the reef face. The tidal dependence of the breaking is interpreted in the context of the point break model in terms of a tidally varying wave height to water depth ratio at breaking. Implications for predictions of wave-driven setup at reef-fringed island shorelines are discussed.

  3. Characteristics of inertial currents observed in offshore wave records

    Science.gov (United States)

    Gemmrich, J.; Garrett, C.

    2012-04-01

    It is well known that ambient currents can change the amplitude, direction and frequency of ocean surface waves. Regions with persistent strong currents, such as the Agulhas current off the east coast of South Africa, are known as areas of extreme waves, and wave height modulations of up to 50% observed in the shallow North Sea have been linked to tidal currents. In the open ocean, inertial currents, while intermittent, are typically the most energetic currents with speeds up to 0.5 m/s, and can interact with the surface wave field to create wave modulation, though this has not previously been reported. We use long records of significant wave heights from buoy observations in the northeast Pacific and show evidence of significant modulation at frequencies that are slightly higher than the local inertial frequency. Quite apart from the relevance to surface waves, this result can provide a consistent and independent measurement, over a wide range of latitudes, of the frequency blue-shift, the strength and intermittency of ocean surface inertial currents. Near-inertial waves constitute the most energetic portion of the internal wave band and play a significant role in deep ocean mixing. So far, observational data on near-surface inertial currents has tended to come from short records that do not permit the reliable determination of the frequency blue-shift, though this is an important factor affecting the energy flux from the surface into deeper waters. Long records from routine wave height observations are widely available and could help to shed new light globally on the blue-shift and on the characteristics of inertial currents.

  4. Between tide and wave marks: a unifying model of physical zonation on littoral shores

    Directory of Open Access Journals (Sweden)

    Christopher E. Bird

    2013-09-01

    Full Text Available The effects of tides on littoral marine habitats are so ubiquitous that shorelines are commonly described as ‘intertidal’, whereas waves are considered a secondary factor that simply modifies the intertidal habitat. However mean significant wave height exceeds tidal range at many locations worldwide. Here we construct a simple sinusoidal model of coastal water level based on both tidal range and wave height. From the patterns of emergence and submergence predicted by the model, we derive four vertical shoreline benchmarks which bracket up to three novel, spatially distinct, and physically defined zones. The (1 emergent tidal zone is characterized by tidally driven emergence in air; the (2 wave zone is characterized by constant (not periodic wave wash; and the (3 submergent tidal zone is characterized by tidally driven submergence. The decoupling of tidally driven emergence and submergence made possible by wave action is a critical prediction of the model. On wave-dominated shores (wave height ≫ tidal range, all three zones are predicted to exist separately, but on tide-dominated shores (tidal range ≫ wave height the wave zone is absent and the emergent and submergent tidal zones overlap substantially, forming the traditional “intertidal zone”. We conclude by incorporating time and space in the model to illustrate variability in the physical conditions and zonation on littoral shores. The wave:tide physical zonation model is a unifying framework that can facilitate our understanding of physical conditions on littoral shores whether tropical or temperate, marine or lentic.

  5. Wave refraction and prediction of breaker parameters along the Kerala Coast, India

    Digital Repository Service at National Institute of Oceanography (India)

    Sajeev, R.; Chandramohan, P.; SanilKumar, V.

    significantly from place to place due to wave refraction and shoaling. The covergence and divergence of wave energy induce non-uniform distribution of wave heights during the monsoon period. Ezhimala promontory causes waves to refract considerably along...

  6. Wave energy converter effects on wave propagation: A sensitivity study in Monterey Bay, CA

    Science.gov (United States)

    Chang, G.; Jones, C. A.; Roberts, J.; Magalen, J.; Ruehl, K.; Chartrand, C.

    2014-12-01

    The development of renewable offshore energy in the United States is growing rapidly and wave energy is one of the largest resources currently being evaluated. The deployment of wave energy converter (WEC) arrays required to harness this resource could feasibly number in the hundreds of individual devices. The WEC arrays have the potential to alter nearshore wave propagation and circulation patterns and ecosystem processes. As the industry progresses from pilot- to commercial-scale it is important to understand and quantify the effects of WECs on the natural nearshore processes that support a local, healthy ecosystem. To help accelerate the realization of commercial-scale wave power, predictive modeling tools have been developed and utilized to evaluate the likelihood of environmental impact. At present, direct measurements of the effects of different types of WEC arrays on nearshore wave propagation are not available; therefore wave model simulations provide the groundwork for investigations of the sensitivity of model results to prescribed WEC characteristics over a range of anticipated wave conditions. The present study incorporates a modified version of an industry standard wave modeling tool, SWAN (Simulating WAves Nearshore), to simulate wave propagation through a hypothetical WEC array deployment site on the California coast. The modified SWAN, referred to as SNL-SWAN, incorporates device-specific WEC power take-off characteristics to more accurately evaluate a WEC device's effects on wave propagation. The primary objectives were to investigate the effects of a range of WEC devices and device and array characteristics (e.g., device spacing, number of WECs in an array) on nearshore wave propagation using SNL-SWAN model simulations. Results showed that significant wave height was most sensitive to variations in WEC device type and size and the number of WEC devices in an array. Locations in the lee centerline of the arrays in each modeled scenario showed the

  7. Memory for target height is scaled to observer height.

    Science.gov (United States)

    Twedt, Elyssa; Crawford, L Elizabeth; Proffitt, Dennis R

    2012-04-01

    According to the embodied approach to visual perception, individuals scale the environment to their bodies. This approach highlights the central role of the body for immediate, situated action. The present experiments addressed whether body scaling--specifically, eye-height scaling--occurs in memory when action is not immediate. Participants viewed standard targets that were either the same height as, taller than, or shorter than themselves. Participants then viewed a comparison target and judged whether the comparison was taller or shorter than the standard target. Participants were most accurate when the standard target height matched their own heights, taking into account postural changes. Participants were biased to underestimate standard target height, in general, and to push standard target height away from their own heights. These results are consistent with the literature on eye-height scaling in visual perception and suggest that body scaling is not only a useful metric for perception and action, but is also preserved in memory.

  8. Storm-wave trends in Mexican waters of the Gulf of Mexico and Caribbean Sea

    Directory of Open Access Journals (Sweden)

    E. Ojeda

    2017-08-01

    Full Text Available Thirty-year time series of hindcast wave data were analysed for 10 coastal locations along the eastern Mexican coast to obtain information about storm events occurring in the region, with the goal of examining the possible presence of interannual trends in the number of storm-wave events and their main features (wave height, duration and energy content. The storms were defined according to their significant wave height and duration, and the events were classified as related to either tropical cyclones or Norte events. The occurrence and characteristics of both types of events were analysed independently. There is no statistically significant change in the number of storm-wave events related to Nortes or their characteristics during the study period. However, there is a subtle increase in the number of events related to tropical cyclones in the western Caribbean region and a more evident increase in wave height and energy content of these events.

  9. Application value of Serum Hs-CRP, IL-6 and plasma FIB joint detection in COPD

    Directory of Open Access Journals (Sweden)

    Feng Ji

    2016-11-01

    Full Text Available Objective: To discuss the application value of High sensitivity C-reactive protein (Hs-CRP, interleukin-6 (IL-6 and fibrinogen (FIB joint detection in chronic obstructive pulmonary disease (COPD. Methods: A total of 181 COPD cases were divided to be COPD stable phase group (65 cases and COPD acute exacerbation phase group (116 cases per the course of disease. COPD acute exacerbation phase group was classified into grade I (39 cases, grade II (43 cases and grade III (34 cases based on pulmonary function. Then survival group (87 cases and death group (29 cases were divided based on illness transition. Meanwhile, 80 cases of healthy people at the same phase were set to be healthy group. Differences in levels of Serum hs-CRP, IL-6 and FIB in these groups were analyzed, and according to these indexes, prognostic potency of COPD acute exacerbation phase could be evaluated. Results: Difference in serum hs-CRP, IL-6 and FIB levels in COPD stable phase group, COPD acute exacerbation phase group and healthy group were statistical significant (P<0.05. both for healthy group hs-CRP, IL-6 and FIB levels in grade I, II, III of pulmonary function in the COPD acute exacerbation phase group were statistical significant (P<0.05 both for grade 1 < grade 2 < grade 3. Result of person analyzing showed significant positive correlation on grading of pulmonary function and serum hs-CRP, IL-6 and FIB levels, the correlation coefficient was 0.573. Differences of hs-CRP, IL-6 and FIB levels between survival group and death group were statistical significant. Serum hs-CRP, IL-6 and FIB levels were utilized respectively to evaluate area under curve of receiver operating characteristic in prognostic COPD acute exacerbation phase group, namely, 0.836, 0.815, 0.776. Sensitivities of “death”, which was evaluated by the various indexes, respectively showed as: 72.41%, 65.51% and 75

  10. Oscillatory infragravity wave contribution to surf zone sediment transport

    DEFF Research Database (Denmark)

    Aagaard, Troels; Greenwood, Brian

    2008-01-01

    . It is shown that infragravity sediment transports are onshore directed at the landward side of relative (incident) wave height maxima, and offshore directed at the seaward side of such maxima. If a longshore infragravity wave structure exists, such as in the case of standing edge waves, the advection process...

  11. Performance of ERA-Interim wave data in the nearshore waters around India

    Digital Repository Service at National Institute of Oceanography (India)

    SanilKumar, V.; Naseef, T.M.

    Bulk wave parameters, such as wave height and wave period, are required for engineering and environmental applications. In this study, measured wave data from six shallow-water locations in the data-sparse north Indian Ocean are used to assess...

  12. Two-Dimensional Analysis of Cable Stayed Bridge under Wave Loading

    Science.gov (United States)

    Seeram, Madhuri; Manohar, Y.

    2018-06-01

    In the present study finite element analysis is performed for a modified fan type cable-stayed bridge using ANSYS Mechanical. A cable stayed bridge with two towers and main deck is considered for the present study. Dynamic analysis is performed to evaluate natural frequencies. The obtained natural frequencies and mode shapes of cable stayed bridge are compared to the existing results. Further studies have been conducted for offshore area application by increasing the pylon/tower height depending upon the water depth. Natural frequencies and mode shapes are evaluated for the cable stayed bridge for offshore area application. The results indicate that the natural periods are higher than the existing results due to the effect of increase in mass of the structure and decrease in stiffness of the pylon/tower. The cable stayed bridge is analyzed under various environmental loads such as dead, live, vehicle, seismic and wave loading. Morison equation is considered to evaluate the wave force. The sum of inertia and drag force is taken as the wave force distribution along the fluid interacting height of the pylon. Airy's wave theory is used to assess water particle kinematics, for the wave periods ranging from 5 to 20 s and unit wave height. The maximum wave force among the different regular waves is considered in the wave load case. The support reactions, moments and deflections for offshore area application are highlighted. It is observed that the maximum support reactions and support moments are obtained due to wave and earthquake loading respectively. Hence, it is concluded that the wave and earthquake forces shall be given significance in the design of cable stayed bridge.

  13. Childhood height, adult height, and the risk of prostate cancer

    DEFF Research Database (Denmark)

    Bjerregaard, Lise Geisler; Aarestrup, Julie; Gamborg, Michael

    2016-01-01

    PURPOSE: We previously showed that childhood height is positively associated with prostate cancer risk. It is, however, unknown whether childhood height exerts its effects independently of or through adult height. We investigated whether and to what extent childhood height has a direct effect...... on the risk of prostate cancer apart from adult height. METHODS: We included 5,871 men with height measured at ages 7 and 13 years in the Copenhagen School Health Records Register who also had adult (50-65 years) height measured in the Danish Diet, Cancer and Health study. Prostate cancer status was obtained...... through linkage to the Danish Cancer Registry. Direct and total effects of childhood height on prostate cancer risk were estimated from Cox regressions. RESULTS: From 1996 to 2012, 429 prostate cancers occurred. Child and adult heights were positively and significantly associated with prostate cancer risk...

  14. The maximum significant wave height in the Southern North Sea

    NARCIS (Netherlands)

    Bouws, E.; Tolman, H.L.; Holthuijsen, L.H.; Eldeberky, Y.; Booij, N.; Ferier, P.

    1995-01-01

    The maximum possible wave conditions along the Dutch coast, which seem to be dominated by the limited water depth, have been estimated in the present study with numerical simulations. Discussions with meteorologists suggest that the maximum possible sustained wind speed in North Sea conditions is

  15. Modelling of wave propagation over a submerged sand bar using SWASH

    Digital Repository Service at National Institute of Oceanography (India)

    Jishad, M.; Vu, T.T.T.; JayaKumar, S.

    cases The wave heights and wave induced velocities obtained from the model and the laboratory experimental resultsare compared The model without the morphology feedback provided good correlation with the measurements for case of low wave energy, whereas...

  16. Effect of flurbiprofen aretilon on serum hs-CRP, IL-6 levels in patients undergoing esophageal cancer surgery

    International Nuclear Information System (INIS)

    Li Jiakai

    2011-01-01

    Objective: To investigate the effect of flurbiprofen axetil on serum high sensitivity C reactive protein (hs-CRP) and interleukin-6 (IL-6) in the patients undergoing esophageal cancer surgery. Methods: Thirty patients were divided into 2 groups with 15 cases each. The patients in groups A were given flurbiprofen axetil and those in group B were not as the controls. Serum hs-CRP (immuno-turbidity method) and IL-6 (RIA) levels were determined before anesthesia induction and after extubation. Results: The levels of serum hs-CRP, IL-6 were significantly higher in group B than those in group A (P<0.05). Conclusion: Flurbiprofen axetil could reduce serum hs-CRP, IL-6 levels in patients undergoing Esophageal cancer surgery. (authors)

  17. Effects of vertical wall and tetrapod weights on wave overtopping in rubble mound breakwaters under irregular wave conditions

    Directory of Open Access Journals (Sweden)

    Park Sang Kil

    2014-12-01

    Full Text Available Rubble mound breakwaters protect the coastal line against severe erosion caused by wave action. This study examined the performance of different sizes and properties (i.e. height of vertical wall and tetrapod size of rubble mound breakwaters on reducing the overtopping discharge. The physical model used in this study was derived based on an actual rubble mound in Busan Yacht Harbor. This research attempts to fill the gap in practical knowledge on the combined effect of the armor roughness and vertical wall on wave overtopping in rubble mound breakwaters. The main governing parameters used in this study were the vertical wall height, variation of the tetrapod weights, initial water level elevation, and the volume of overtopping under constant wave properties. The experimental results showed that the roughness factor differed according to the tetrapod size. Furthermore, the overtopping discharge with no vertical wall was similar to that with relatively short vertical walls ( 1 γv = 1. Therefore, the experimental results highlight the importance of the height of the vertical wall in reducing overtopping discharge. Moreover, a large tetrapod size may allow coastal engineers to choose a shorter vertical wall to save cost, while obtaining better performance.

  18. Effects of vertical wall and tetrapod weights on wave overtopping in rubble mound breakwaters under irregular wave conditions

    Directory of Open Access Journals (Sweden)

    Sang Kil Park

    2014-12-01

    Full Text Available Rubble mound breakwaters protect the coastal line against severe erosion caused by wave action. This study examined the performance of different sizes and properties (i.e. height of vertical wall and tetrapod size of rubble mound breakwaters on reducing the overtopping discharge. The physical model used in this study was derived based on an actual rubble mound in Busan Yacht Harbor. This research attempts to fill the gap in practical knowledge on the combined effect of the armor roughness and vertical wall on wave overtopping in rubble mound breakwaters. The main governing parameters used in this study were the vertical wall height, variation of the tetrapod weights, initial water level elevation, and the volume of overtopping under constant wave properties. The experimental results showed that the roughness factor differed according to the tetrapod size. Furthermore, the overtopping discharge with no vertical wall was similar to that with relatively short vertical walls (γν = 1. Therefore, the experimental results highlight the importance of the height of the vertical wall in reducing overtopping discharge. Moreover, a large tetrapod size may allow coastal engineers to choose a shorter vertical wall to save cost, while obtaining better performance.

  19. Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated in vitro in cell cultures.

    Science.gov (United States)

    Shubber, Saif; Vllasaliu, Driton; Rauch, Cyril; Jordan, Faron; Illum, Lisbeth; Stolnik, Snjezana

    2015-02-01

    CriticalSorb™, with the principal component Solutol® HS15, is a novel mucosal drug delivery system demonstrated to improve the bioavailability of selected biotherapeutics. The intention of this study is to elucidate mechanism(s) responsible for the enhancement of trans-mucosal absorption of biological drugs by Solutol® HS15. Micelle size and CMC of Solutol® HS15 were determined in biologically relevant media. Polarised airway Calu-3 cell layers were used to measure the permeability of a panel of biological drugs, and to assess changes in TEER, tight junction and F-actin morphology. The rate of cell endocytosis was measured in vitro in the presence of Solutol® HS15 using a membrane probe, FM 2-10. This work initially confirms surfactant-like behaviour of Solutol® HS15 in aqueous media, while subsequent experiments demonstrate that the effect of Solutol® HS15 on epithelial tight junctions is different from a 'classical' tight junction opening agent and illustrate the effect of Solutol® HS15 on the cell membrane (endocytosis rate) and F-actin cytoskeleton. Solutol® HS15 is the principle component of CriticalSorb™ that has shown an enhancement in permeability of medium sized biological drugs across epithelia. This study suggests that its mechanism of action arises primarily from effects on the cell membrane and consequent impacts on the cell cytoskeleton in terms of actin organisation and tight junction opening.

  20. Numerical simulation of nonlinear wave force on a quasi-ellipse caisson

    Science.gov (United States)

    Wang, Yongxue; Ren, Xiaozhong; Wang, Guoyu

    2011-09-01

    A three dimensional numerical model of nonlinear wave action on a quasi-ellipse caisson in a time domain was developed in this paper. Navier-Stokes equations were solved by the finite difference method, and the volume of fluid (VOF) method was employed to trace the free surface. The partial cell method was used to deal with the irregular boundary typical of this type of problem during first-time wave interaction with the structure, and a satisfactory result was obtained. The numerical model was verified and used to investigate the effects of the relative wave height H/d, relative caisson width kD, and relative length-width ratio B/D on the wave forces of the quasi-ellipse caisson. It was shown that the relative wave height H/d has a significant effect on the wave forces of the caisson. Compared with the non-dimensional inline wave force, the relative length-width ratio B/D was shown to have significant influence on the non-dimensional transverse wave force.

  1. The Value of HbA1c and hs-CRP Combined Detection in Diagnosis of Diabetic Retinopathy%HbA1c、hs-CRP 联合检测诊断糖尿病视网膜病变的价值

    Institute of Scientific and Technical Information of China (English)

    李孝才; 孙学芬; 吴建霞; 马雪燕

    2016-01-01

    目的:探讨糖化血红蛋白(HbA1c)和高敏 C 反应蛋白(hs-CRP)联合检测诊断糖尿病视网膜病变的价值。方法:选择正常体检者(A 组)、糖尿病无视网膜病变者(B 组)、糖尿病视网膜病变者(C 组)各72例,采用离子交换液相层析法和胶乳增强免疫比浊法测定 HbA1c 及 hs-CRP。结果:无视网膜病变组和视网膜病变组的 HbA1c 和 hs-CRP(mg/L)含量均比健康对照组高,具有统计学意义(P0.05);但是 HbA1c +Hs-CRP 诊断糖尿病视网膜病变的特异为90.3%,分别与 HbA1c 和 hs-CRP 存在明显差异(P 0.05); but specific to the HbA1c of hs CRP in the diagnosis of diabetic retinopathy was 90.3%, respectively and hs CRP and HbA1c exist significant difference (P< 0.05). Conclusion:The detection of HBA1c and Hs-CRPis helpful to early detection of diabetic retinopathy, which can be used asmonitoring indicators for progress and treatment effect in type 2 diabetes mellitus patients.

  2. Experimental investigation on the hydrodynamic performance of a wave energy converter

    Science.gov (United States)

    Zheng, Xiong-bo; Ma, Yong; Zhang, Liang; Jiang, Jin; Liu, Heng-xu

    2017-06-01

    Wave energy is an important type of marine renewable energy. A wave energy converter (WEC) moored with two floating bodies was developed in the present study. To analyze the dynamic performance of the WEC, an experimental device was designed and tested in a tank. The experiment focused on the factors which impact the motion and energy conversion performance of the WEC. Dynamic performance was evaluated by the relative displacements and velocities of the oscillator and carrier which served as the floating bodies of WEC. Four factors were tested, i.e. wave height, wave period, power take-off (PTO) damping, and mass ratio ( R M) of the oscillator and carrier. Experimental results show that these factors greatly affect the energy conversion performance, especially when the wave period matches R M and PTO damping. According to the results, we conclude that: (a) the maximization of the relative displacements and velocities leads to the maximization of the energy conversion efficiency; (b) the larger the wave height, the higher the energy conversion efficiency will be; (c) the relationships of energy conversion efficiency with wave period, PTO damping, and R M are nonlinear, but the maximum efficiency is obtained when these three factors are optimally matched. Experimental results demonstrated that the energy conversion efficiency reached the peak at 28.62% when the wave height was 120 mm, wave period was 1.0 s, R M was 0.21, and the PTO damping was corresponding to the resistance of 100 Ω.

  3. Verification of model wave heights with long-term moored buoy data: Application to wave field over the Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Samiksha, S.V.; Polnikov, V.G.; Vethamony, P.; Rashmi, R.; Pogarskii, F.; Sudheesh, K.

    . Res. 106(C6), 11659-11676 Babanin, A.V., 2011. Breaking and Dissipation of Ocean Surface Waves. Book, Cambridge University Press, 480p Banner, M. L., Gemmrich, J. R., and Farmer, D. M., 2002. Multiscale measurements of ocean wave breaking...

  4. Effects of wave-current interaction on storm surge in the Taiwan Strait: Insights from Typhoon Morakot

    Science.gov (United States)

    Yu, Xiaolong; Pan, Weiran; Zheng, Xiangjing; Zhou, Shenjie; Tao, Xiaoqin

    2017-08-01

    The effects of wave-current interaction on storm surge are investigated by a two-dimensional wave-current coupling model through simulations of Typhoon Morakot in the Taiwan Strait. The results show that wind wave and slope of sea floor govern wave setup modulations within the nearshore surf zone. Wave setup during Morakot can contribute up to 24% of the total storm surge with a maximum value of 0.28 m. The large wave setup commonly coincides with enhanced radiation stress gradient, which is itself associated with transfer of wave momentum flux. Water levels are to leading order in modulating significant wave height inside the estuary. High water levels due to tidal change and storm surge stabilize the wind wave and decay wave breaking. Outside of the estuary, waves are mainly affected by the current-induced modification of wind energy input to the wave generation. By comparing the observed significant wave height and water level with the results from uncoupled and coupled simulations, the latter shows a better agreement with the observations. It suggests that wave-current interaction plays an important role in determining the extreme storm surge and wave height in the study area and should not be neglected in a typhoon forecast.

  5. Nearly simultaneous measurements of radar auroral heights and Doppler velocities at 398 MHz

    International Nuclear Information System (INIS)

    Moorcroft, D.; Ruohoniemi, J.M.

    1987-01-01

    Nearly simultaneous measurements of radar auroral heights and Doppler velocities were obtained using the Homer, Alaska, 398-MHz phased-array radar over a total of 16 hours on four different days. The heights show a consistent variation with time, being highest near the time of electrojet current reversal, and lowest late in the morning. A variety of east-west height asymmetries were observed, different from those previously reported, which can be explained in terms of favorable flow angles preferentially favoring high-altitude primary two-stream waves to one side of the field of view. Low-velocity echoes, presumably due to secondary irregularities, are found to be more restricted in height range than echoes with ion acoustic velocities, which presumably come from primary two-stream instabilities. Echo power was examined as a function of velocity and height. For the westward electrojet it was found that echoes with ion acoustic velocities are relatively constant in strength over most of their height range, but for low-velocity echoes the power is a maximum between 100 and 105 km and falls off steadily at greater heights. Doppler speeds show a noticeable decrease at heights below 105 km, in agreement with the expected variation in ion acoustic velocity

  6. Fall from heights: does height really matter?

    Science.gov (United States)

    Alizo, G; Sciarretta, J D; Gibson, S; Muertos, K; Romano, A; Davis, J; Pepe, A

    2018-06-01

    Fall from heights is high energy injuries and constitutes a fraction of all fall-related trauma evaluations while bearing an increase in morbidity and mortality. We hypothesize that despite advancements in trauma care, the overall survivability has not improved in this subset of trauma patients. All adult trauma patients treated after sustaining a fall from heights during a 40-month period were retrospectively reviewed. Admission demographics, clinical data, fall height (ft), injury patterns, ISS, GCS, length of stay, and mortality were reviewed. 116 patients sustained a fall from heights, 90.4% accidental. A mean age of 37± 14.7 years, 86% male, and a fall height of 19 ± 10 ft were encountered. Admission GCS was 13 ± 2 with ISS 10 ± 11. Overall LOS was 6.6 ± 14.9 days and an ICU LOS of 2.8 ± 8.9 days. Falls ≥ 25 ft.(16%) had lower GCS 10.4 ± 5.8, increased ISS 22.6 ± 13.8, a fall height 37.9 ± 13.1 ft and associated increased mortality (p < 0.001). Mortality was 5.2%, a mean distance fallen of 39 ± 22 ft. and an ISS of 31.5 ±16.5. Brain injury was the leading cause of death, 50% with open skull fractures. Level of height fallen is a good predictor of overall outcome and survival. Despite advances in trauma care, death rates remain unchanged. Safety awareness and injury prevention programs are needed to reduce the risk of high-level falls.

  7. In vitro investigation on the impact of Solutol HS 15 on the uptake of colchicine into rat hepatocytes.

    Science.gov (United States)

    Bravo González, Roberto Carlos; Boess, Franziska; Durr, Evelyne; Schaub, Nathalie; Bittner, Beate

    2004-07-26

    In the current investigation, the impact of the surface-active formulation ingredient Solutol HS 15 on the uptake of colchicine into freshly isolated rat hepatocytes was investigated using a centrifugal filtration technique through a silicone oil layer. Colchicine is taken up into the cells by an active transport mechanism. When conducting the experiment at 37 degrees C, it was found that at concentrations below its critical micellar concentration (CMC) of 0.021% (0.0003 and 0.003%, w/v), Solutol HS 15 did not impact the uptake of colchicine. By contrast, at a Solutol HS 15 concentration above its CMC (0.03%, w/v), the amount of colchicine taken up into the cells as well as its uptake velocity were significantly decreased. However, in control experiments performed at 4 degrees C, a temperature at which active transport processes should be significantly slowed down, Solutol HS 15 at 0.03% did not affect colchicine uptake and/or its association with the cells. The described findings might be rationalized by inhibition of colchicine transport either due to direct interaction at the transport site or due to alterations of membrane properties in the presence of Solutol HS 15 at concentrations above its CMC. Moreover, a strong molecular interaction between Solutol HS 15 and colchicine as well as an incorporation of colchicine into micelles formed by Solutol HS 15, this way resulting in a limited contact of colchicine with the cells, cannot be excluded as contributors to the observed effect.

  8. The carriage of potentially pathogenic β-haemolytic streptococci (β-HS in healthy adult inhabitants of Wielkopolska, Poland

    Directory of Open Access Journals (Sweden)

    Maciej Bura

    2016-09-01

    Full Text Available Background . Acute pharyngitis is a common disease in primary health care patients. Beta-hemolytic streptococci (β-HS are a frequent etiological agent, while swab culture from the throat and palatine tonsils is the gold standard for diagnosis. Objectives. The evaluation of the prevalence of potentially pathogenic β-HS carriage in young adult inhabitants of Wielkopolska. Material and methods. The study included 205 healthy young adult (18–44 years old (29.0 ± 6.4 inhabitants (M – 95, F – 110 of Wielkopolska (Poland. Two swabs were taken from the throat: the first one was used to perform a rapid antigenic diagnostic test (RAD T for group A streptococci (GAS and the second to grow a conventional culture. If β-HS grew, isolates were serotyped according to Lancefield. In addition, simple demographic and medical data were collected from the subjects. The study was financed from funds granted within the first edition of the “Give a hand” project (Karol Marcinkowski Poznan University of Medical Sciences. Results . Positive throat cultures were obtained in 15.6% out of 205 persons (n = 32. The distribution of β-HS serogroup results was as follows: group C (GCS – 17 cases (53.1% of cases where β-HS was positive, group F (GFS – 9 cases (28.1%, GAS – 3 people (9.4% and group G (GGS – 3 subjects (9.4%. The growth of the discussed bacteria in cultures was moderate or high in 53% of these cases. RAD T was positive in 5 cases (but only one person had GAS in throat culture. The positive culture result was significantly more frequent in men (62.5% out of 32 cases with β-HS growth, p = 0.0460. Conclusions . 1. The possibility of β-HS carriage must be taken into account when analysing the results of throat swab cultures. 2. GAS carriage is significantly lower than non-GAS carriage. 3. GCS were the most prevalent among non-GAS. 4. Being male may predispose individuals to β-HS carriage.

  9. Wave energy and its possibilities in the Danish power supplies

    International Nuclear Information System (INIS)

    Traeholt Madsen, N.; Lorenzen, S.; Haunstrup Christensen, T.

    1997-06-01

    Mathematical theory of wave forces (wave height, spectrua, energy distribution and effect) is summarized. An attempt to estimate the Danish wave power potential on the basis of previous investigations og wave effect in various regions is presented. A brief review of wave energy applications and research constitutes basis for two scenarios of wave power adjustment into the 'Green society'. Power quality, environment, economics and supply reliability are estimated. (EG) 42 refs

  10. Characteristics of waves off Goa, west coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    SanilKumar, V.; AshokKumar, K.; Anand, N.M.

    Directional wave measurements were carried out using Datawell directional waverider buoy off Goa along west coast of India during the south west monsoon period in 1996 and the results are presented. Theoretical joint distribution of wave height...

  11. ON THE SPATIAL SCALES OF WAVE HEATING IN THE SOLAR CHROMOSPHERE

    International Nuclear Information System (INIS)

    Soler, Roberto; Ballester, Jose Luis; Carbonell, Marc

    2015-01-01

    Dissipation of magnetohydrodynamic (MHD) wave energy has been proposed as a viable heating mechanism in the solar chromospheric plasma. Here, we use a simplified one-dimensional model of the chromosphere to theoretically investigate the physical processes and spatial scales that are required for the efficient dissipation of Alfvén waves and slow magnetoacoustic waves. We consider the governing equations for a partially ionized hydrogen-helium plasma in the single-fluid MHD approximation and include realistic wave damping mechanisms that may operate in the chromosphere, namely, Ohmic and ambipolar magnetic diffusion, viscosity, thermal conduction, and radiative losses. We perform an analytic local study in the limit of small amplitudes to approximately derive the lengthscales for critical damping and efficient dissipation of MHD wave energy. We find that the critical dissipation lengthscale for Alfvén waves depends strongly on the magnetic field strength and ranges from 10 m to 1 km for realistic field strengths. The damping of Alfvén waves is dominated by Ohmic diffusion for weak magnetic field and low heights in the chromosphere, and by ambipolar diffusion for strong magnetic field and medium/large heights in the chromosphere. Conversely, the damping of slow magnetoacoustic waves is less efficient, and spatial scales shorter than 10 m are required for critical damping. Thermal conduction and viscosity govern the damping of slow magnetoacoustic waves and play an equally important role at all heights. These results indicate that the spatial scales at which strong wave heating may work in the chromosphere are currently unresolved by observations

  12. ON THE SPATIAL SCALES OF WAVE HEATING IN THE SOLAR CHROMOSPHERE

    Energy Technology Data Exchange (ETDEWEB)

    Soler, Roberto; Ballester, Jose Luis [Departament de Física, Universitat de les Illes Balears, E-07122, Palma de Mallorca (Spain); Carbonell, Marc, E-mail: roberto.soler@uib.es [Institute of Applied Computing and Community Code (IAC), Universitat de les Illes Balears, E-07122, Palma de Mallorca (Spain)

    2015-09-10

    Dissipation of magnetohydrodynamic (MHD) wave energy has been proposed as a viable heating mechanism in the solar chromospheric plasma. Here, we use a simplified one-dimensional model of the chromosphere to theoretically investigate the physical processes and spatial scales that are required for the efficient dissipation of Alfvén waves and slow magnetoacoustic waves. We consider the governing equations for a partially ionized hydrogen-helium plasma in the single-fluid MHD approximation and include realistic wave damping mechanisms that may operate in the chromosphere, namely, Ohmic and ambipolar magnetic diffusion, viscosity, thermal conduction, and radiative losses. We perform an analytic local study in the limit of small amplitudes to approximately derive the lengthscales for critical damping and efficient dissipation of MHD wave energy. We find that the critical dissipation lengthscale for Alfvén waves depends strongly on the magnetic field strength and ranges from 10 m to 1 km for realistic field strengths. The damping of Alfvén waves is dominated by Ohmic diffusion for weak magnetic field and low heights in the chromosphere, and by ambipolar diffusion for strong magnetic field and medium/large heights in the chromosphere. Conversely, the damping of slow magnetoacoustic waves is less efficient, and spatial scales shorter than 10 m are required for critical damping. Thermal conduction and viscosity govern the damping of slow magnetoacoustic waves and play an equally important role at all heights. These results indicate that the spatial scales at which strong wave heating may work in the chromosphere are currently unresolved by observations.

  13. Observations of wave transformation over a fringing coral reef and the importance of low-frequency waves and offshore water levels to runup, overwash, and coastal flooding

    Science.gov (United States)

    Cheriton, Olivia; Storlazzi, Curt; Rosenberger, Kurt

    2016-01-01

    Many low-lying tropical islands are susceptible to sea level rise and often subjected to overwash and flooding during large wave events. To quantify wave dynamics and wave-driven water levels on fringing coral reefs, a 5 month deployment of wave gauges and a current meter was conducted across two shore-normal transects on Roi-Namur Island in the Republic of the Marshall Islands. These observations captured two large wave events that had waves with maximum heights greater than 6 m with peak periods of 16 s over the fore reef. The larger event coincided with a peak spring tide, leading to energetic, highly skewed infragravity (0.04–0.004 Hz) and very low frequency (0.004–0.001 Hz) waves at the shoreline, which reached heights of 1.0 and 0.7 m, respectively. Water surface elevations, combined with wave runup, reached 3.7 m above the reef bed at the innermost reef flat adjacent to the toe of the beach, resulting in flooding of inland areas. This overwash occurred during a 3 h time window that coincided with high tide and maximum low-frequency reef flat wave heights. The relatively low-relief characteristics of this narrow reef flat may further drive shoreline amplification of low-frequency waves due to resonance modes. These results (1) demonstrate how the coupling of high offshore water levels with low-frequency reef flat wave energetics can lead to large impacts along fringing reef-lined shorelines, such as island overwash, and (2) lend support to the hypothesis that predicted higher sea levels will lead to more frequent occurrences of these extreme events, negatively impacting coastal resources and infrastructure.

  14. Observations of wave transformation over a fringing coral reef and the importance of low-frequency waves and offshore water levels to runup, overwash, and coastal flooding

    Science.gov (United States)

    Cheriton, Olivia M.; Storlazzi, Curt D.; Rosenberger, Kurt J.

    2016-05-01

    Many low-lying tropical islands are susceptible to sea level rise and often subjected to overwash and flooding during large wave events. To quantify wave dynamics and wave-driven water levels on fringing coral reefs, a 5 month deployment of wave gauges and a current meter was conducted across two shore-normal transects on Roi-Namur Island in the Republic of the Marshall Islands. These observations captured two large wave events that had waves with maximum heights greater than 6 m with peak periods of 16 s over the fore reef. The larger event coincided with a peak spring tide, leading to energetic, highly skewed infragravity (0.04-0.004 Hz) and very low frequency (0.004-0.001 Hz) waves at the shoreline, which reached heights of 1.0 and 0.7 m, respectively. Water surface elevations, combined with wave runup, reached 3.7 m above the reef bed at the innermost reef flat adjacent to the toe of the beach, resulting in flooding of inland areas. This overwash occurred during a 3 h time window that coincided with high tide and maximum low-frequency reef flat wave heights. The relatively low-relief characteristics of this narrow reef flat may further drive shoreline amplification of low-frequency waves due to resonance modes. These results (1) demonstrate how the coupling of high offshore water levels with low-frequency reef flat wave energetics can lead to large impacts along fringing reef-lined shorelines, such as island overwash, and (2) lend support to the hypothesis that predicted higher sea levels will lead to more frequent occurrences of these extreme events, negatively impacting coastal resources and infrastructure.

  15. Clinical diagnostic value of determination of plasma ET, Hcy and serum hs-CRP contents in patients with coronary heart diseases

    International Nuclear Information System (INIS)

    Chu Jingying; Zhu Xueming

    2008-01-01

    Objective: To study the clinical diagnostic value of determination of plasma ET, Hcy and serum hs-CRP contents in patients with coronary heart disease (CHD). Methods: Plasma ET, Hcy(with RIA) and serum hs-CRP (with immune turbidimetry) contents were determined in 38 patients with CHD and 35 controls. Results: Plasma ET, Hcy and serum hs-CRP concentration were significantly higher in CHD patients (than those in controls P<0.01). Plasma ET levels were significantly positively correlated with those of plasma Hcy and serum hs-CRP (r=0.6122, 0.5842, P<0.01). Conclusion: Detection of changes of plasma ET, Hcy and serum hs-CRP levels might be of prognostic importance in patients with CHD. (authors)

  16. Variability in wave refraction and resultant nearshore current patterns: Exposed versus sheltered beaches along north Karnataka, west coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Veerayya, M.; Pankajakshan, T.

    of wave heights in headland-bays and at river mouths. Certain stretches of open ocean beaches located on either side of the Kali River and the headland-bay beaches south of Karwar Head experience relatively higher wave heights for W and WSW waves...

  17. Sensitivity of wave energy to climate change

    OpenAIRE

    Harrison, Gareth; Wallace, Robin

    2005-01-01

    Wave energy will have a key role in meeting renewable energy targets en route to a low carbon economy. However, in common with other renewables, it may be sensitive to changes in climate resulting from rising carbon emissions. Changes in wind patterns are widely anticipated and this will ultimately alter wave regimes. Indeed, evidence indicates that wave heights have been changing over the last 40 years, although there is no proven link to global warming. Changes in the wave climate will impa...

  18. Protective activity of a novel resveratrol analogue, HS-1793, against DNA damage in 137Cs-irradiated CHO-K1 cells

    International Nuclear Information System (INIS)

    Jeong, Min Ho; Jo, Young Rae; Yang, Kwang Mo; Jeong, Dong Hyeok; Lee, Chang Geun; Oh, Su Jung; Jeong, Soo Kyung; Jo, Wol Soon; Lee, Ki Won

    2014-01-01

    Resveratrol has received considerable attention as a polyphenol with anti-oxidant, anti-carcinogenic, and anti-inflammatory effects. Radiation is an important component of therapy for a wide range of malignant conditions. However, it causes damage to normal cells and, hence, can result in adverse side effects. This study was conducted to examine whether HS-1793, a novel resveratrol analogue free from the restriction of metabolic instability and the high dose requirement of resveratrol, induces a protective effect against radiation-induced DNA damage. HS-1793 effectively scavenged free radicals and inhibited radiation-induced plasmid DNA strand breaks in an in vitro assay. HS-1793 significantly decreased reactive oxygen species and cellular DNA damage in 2 Gy-irradiated Chinese hamster ovary (CHO)-K1 cells. In addition, HS-1793 dose-dependently reduced the levels of phosphorylated H2AX in irradiated CHO-K1 cells. These results indicate that HS-1793 has chemical radioprotective activity. Glutathione levels and superoxide dismutase activity in irradiated CHO-K1 cells increased significantly following HS-1793 treatment. The enhanced biological anti-oxidant activity and chemical radioprotective activity of HS-1793 maintained survival of irradiated CHO-K1 cells in a clonogenic assay. Therefore, HS-1793 may be of value as a radioprotector to protect healthy tissue surrounding tumor cells during radiotherapy to obtain better tumor control with a higher dose. (author)

  19. The relevance of the whitecapping term in wave forecasting. An analysis for the wave period of the Catalan coast.

    Science.gov (United States)

    Pallares, Elena; Espino, Manuel; Sánchez-Arcilla, Agustín

    2013-04-01

    The Catalan Coast is located in the North Western Mediterranean Sea. It is a region with highly heterogeneous wind and wave conditions, characterized by a microtidal environment, and economically very dependent from the sea and the coastal zone activities. Because some of the main coastal conflicts and management problems occur within a few kilometers of the land-ocean boundary, the level of resolution and accuracy from meteo-oceanographic predictions required is not currently available. The current work is focused on improving high resolution wave forecasting very near the coast. The SWAN wave model is used to simulate the waves in the area, and various buoy data and field campaigns are used to validate the results. The simulations are structured in four different domains covering all the North Western Mediterranean Sea, with a grid resolution from 9 km to 250 meters in coastal areas. Previous results show that the significant wave height is almost always underpredicted in this area, and the underprediction is higher during storm events. However, the error in the peak period and the mean period is almost always constantly under predicted with a bias between one and two seconds, plus some residual error. This systematic error represents 40% of the total error. To improve the initial results, the whiteccaping dissipation term is studied and modified. In the SWAN model, the whitecapping is mainly controlled by the steepness of the waves. Although the by default parameter is not depending on the wave number, there is a new formulation in the last SWAN version (40.81) to include it in the calculations. Previous investigations show that adjusting the dependence for the wave number improved the predictions for the wave energy at lower frequencies, solving the underprediction of the period mentioned before. In the present work different simulations are developed to calibrate the new formulation, obtaining important improvements in the results. For the significant wave

  20. Comparative analysis of the aroma chemicals of Melissa officinalis using hydrodistillation and HS-SPME techniques

    Directory of Open Access Journals (Sweden)

    Shakeel-u- Rehman

    2017-05-01

    Full Text Available Headspace solid-phase micro extraction (HS-SPME coupled with gas chromatography–mass spectrometry (GC–MS has been used for the chemical analysis of Melissa officinalis (leaves cultivated in Institute Germplasm. The HS-SPME analysis led to the identification of 22 components constituting 99.1% of the total volatile constituents present in the leaves whereas its hydrodistillate led to the identification of 24 volatile constituents constituting 98.1% of the volatile material. The chemical composition of the SPME and hydrodistilled extract of M. officinalis leaves comprised mainly of oxygenated monoterpenes (78.5% and 57.8% respectively and sesquiterpene hydrocarbons (14.9% and 29.7% respectively. The major components identified in the HS-SPME extract were citronellal (31.1%, citronellol (18.3%, β-caryophyllene (12.0%, (E-citral (11.9%, (Z-citral (9.6%, geraniol (3.6%, (Z-β-ocimene (3.1% and 1-octen-3-ol (2.0% whereas hydrodistilled essential oil was rich in (Z-citral (19.6%, β-caryophyllene (13.2%, (E-citral (11.2%, citronellal (10.2%, germacrene-d (8.3%, δ-3-carene (5.0%, 6-methyl-5-hepten-2-one (3.7% and citronellyl acetate (3.7%. The comparative analysis of volatile constituents of M. officinalis leaf extract using HS-SPME and hydrodistillation techniques shows both qualitative as well as quantitative differences. The current study is the first report involving rapid analysis of volatile components of M. officinalis by HS-SPME.

  1. Wind waves in the Black Sea: results of a hindcast study

    Science.gov (United States)

    Arkhipkin, V. S.; Gippius, F. N.; Koltermann, K. P.; Surkova, G. V.

    2014-11-01

    In this study we describe the wind wave fields in the Black Sea. The general aims of the work were the estimation of statistical wave parameters and the assessment of interannual and seasonal wave parameter variability. The domain of this study was the entire Black Sea. Wave parameters were calculated by means of the SWAN wave model on a 5 × 5 km rectangular grid. Initial conditions (wind speed and direction) for the period between 1949 and 2010 were derived from the NCEP/NCAR reanalysis. According to our calculations the average significant wave height on the Black Sea does not exceed 0.7 m. Areas of most significant heavy sea are the southwestern and the northeastern parts of the sea as expressed in the spatial distribution of significant wave heights, wave lengths and periods. Besides, long-term annual variations of wave parameters were estimated. Thus, linear trends of the annual total duration of storms and of their quantity are nearly stable over the hindcast period. However, an intensification of storm activity is observed in the 1960s-1970s.

  2. Application of a Spectral Wave Model to Assess Breakwater Configurations at a Small Craft Harbour on Lake Ontario

    Directory of Open Access Journals (Sweden)

    Amelia H. Cooper

    2016-08-01

    Full Text Available A surface wave model using three nested grids is applied to the eastern end of Lake Ontario to investigate wave propagation from an open lake environment to a small craft harbour protected by a breakwater. The Simulating WAves Nearshore (SWAN spectral wave model, coupled with the Delft3D hydrodynamic model, is applied to simulate a series of storms in November, 2013. The model results are compared to observations from two pressure sensors, and used to quantify wave properties around existing and future breakwaters to evaluate the bulk changes to the harbour configuration. Overall, the results indicate that the rubblemound breakwater reduces wave heights in the existing harbour by 63% compared to no breakwater, and that the addition of a surface breakwater extension could reduce wave heights by an additional 54%. Wave height attenuation was found to be highly dependent on the incident wave direction relative to breakwater orientation. The spectral wave model is useful for simulating wave transformation for broad directional spectra in wind-sea conditions over large scales to semi-protected areas such as small craft harbours.

  3. Book review: Extreme ocean waves

    Science.gov (United States)

    Geist, Eric L.

    2011-01-01

    ‘‘Extreme Ocean Waves’’ is a collection of ten papers edited by Efim Pelinovsky and Christian Kharif that followed the April 2007 meeting of the General Assembly of the European Geosciences Union. A note on terminology: extreme waves in this volume broadly encompass different types of waves, includ- ing deep-water and shallow-water rogue waves (alternatively termed freak waves), storm surges from cyclones, and internal waves. Other types of waves such as tsunamis or rissaga (meteotsunamis) are not discussed in this volume. It is generally implied that ‘‘extreme’’ has a statistical connotation relative to the average or significant wave height specific to each type of wave. Throughout the book, in fact, the reader will find a combination of theoretical and statistical/ empirical treatment necessary for the complete examination of this subject. In the introduction, the editors underscore the importance of studying extreme waves, documenting several dramatic instances of damaging extreme waves that occurred in 2007. 

  4. CriticalSorb: a novel efficient nasal delivery system for human growth hormone based on Solutol HS15.

    Science.gov (United States)

    Illum, Lisbeth; Jordan, Faron; Lewis, Andrew L

    2012-08-20

    The absorption enhancing efficiency of CriticalSorb for human growth hormone (MW 22 kDa) was investigated in the conscious rat model. The principle absorption enhancing component of CriticalSorb, Solutol HS15, comprises polyglycol mono- and di-esters of 12-hydroxystearic acid combined with free polyethylene glycol. When administering hGH nasally in rats with increasing concentrations of Solutol HS15, it was found that for a 10%w/v solution formulation a bioavailability of 49% was obtained in the first 2h after administration. Furthermore it was shown that the most effective ratio of Solutol HS15 to hGH was 4:1 on a mg to mg basis. Histopathology studies in rats after 5 days repeated nasal administration showed that Solutol HS15 had no toxic effect on the nasal mucosa. These results have been confirmed in a 6 month repeat nasal toxicity study in rats. It can be concluded that the principle absorption enhancing component of CriticalSorb - Solutol HS15 - is a potent and non- toxic nasal absorption enhancer that warrants further development. Copyright © 2012 Elsevier B.V. All rights reserved.

  5. Numerical Modeling of Infragravity Wave Runup on Steep and Mildly Sloping Natural Beaches

    Science.gov (United States)

    Fiedler, J. W.; Smit, P.; Brodie, K. L.; McNinch, J.; Guza, R. T.; Gallien, T.

    2016-12-01

    We present ongoing work which aims to validate the non-hydrostatic model SWASH for wave runup and infragravity waves generated by a range of different incident wave spectra at the offshore boundary, including the effect of finite directional spread. Flume studies of wave runup are limited to normally incident (1D) sea and infragravity waves, but natural waves are directionally spread (2D), with substantially different dynamics from 1D. For example, refractive trapping (edge waves) is only possible with 2D waves, and the bound infragravity wave response to short wave groups is highly amplified for the special case of normal incidence. Selected case studies are modeled at Agate Beach, Oregon, a low slope (1:80) beach with maximum offshore wave heights greater than 7m, and Cardiff, California, a steep (1:8) beach with maximum wave heights of 2m. Peak periods ranged between 5-20 s at both sites. On both beaches, waves were measured on a transect from approximately 10m depth to the runup, using pressure sensors, current meters, and a scanning lidar. Bulk short wave quantities, wave runup, infragravity frequency spectra and energy fluxes are compared with SWASH. On the low slope beach with energetic incident waves, the observed horizontal runup excursions reach 140m ( 100s periods). Swash front velocities reached up to several m/s, causing short waves to stack up during runup drawdown. On reversal of the infragravity phase, the stacked short waves are swept onshore with the long wave front, effectively enhancing runup by phase coupling long and short waves. Statistical variability and nonlinearity in swash generation lead to time-varying runup heights. Here, we test these observations with 2D SWASH, as well as the sensitivity of modeled runup to the parameterization of bottom friction.

  6. A wave model test bed study for wave energy resource characterization

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Zhaoqing; Neary, Vincent S.; Wang, Taiping; Gunawan, Budi; Dallman, Annie R.; Wu, Wei-Cheng

    2017-12-01

    This paper presents a test bed study conducted to evaluate best practices in wave modeling to characterize energy resources. The model test bed off the central Oregon Coast was selected because of the high wave energy and available measured data at the site. Two third-generation spectral wave models, SWAN and WWIII, were evaluated. A four-level nested-grid approach—from global to test bed scale—was employed. Model skills were assessed using a set of model performance metrics based on comparing six simulated wave resource parameters to observations from a wave buoy inside the test bed. Both WWIII and SWAN performed well at the test bed site and exhibited similar modeling skills. The ST4 package with WWIII, which represents better physics for wave growth and dissipation, out-performed ST2 physics and improved wave power density and significant wave height predictions. However, ST4 physics tended to overpredict the wave energy period. The newly developed ST6 physics did not improve the overall model skill for predicting the six wave resource parameters. Sensitivity analysis using different wave frequencies and direction resolutions indicated the model results were not sensitive to spectral resolutions at the test bed site, likely due to the absence of complex bathymetric and geometric features.

  7. Development of a GSI-Based, 2D-VAR Data Assimilation System for Operational Wave Guidance at the National Weather Service

    Science.gov (United States)

    Flampouris, S.; Alves, H.; Pondeca, M.

    2016-02-01

    The US National Centers for Environmental Prediction (NCEP) provides wave guidance to the National Weather Service (NWS) via a suite of operational wave models, which include three global-scale systems. An approach is being developed to include data assimilation into the global wave models using a 2D version of NCEP's grid-point statistical interpolation (2D-GSI), as described in Derber & Rosatti (1989), and Pondeca et al (2011). As a first step to the global implementation of a wave DA system, a prototype is being developed that will consist of adding wave heights as an analysis variable to the operational Real-Time Mesoscale Analysis (RTMA), which provides hourly analyses of several near sea-surface meteorological parameters, and supports a variety of applications within the NWS. The core of the RTMA is a 2D version of the GSI, which is a variational data assimilation system, and the first guess for the wave-height analysis is provided by NCEP's global wave models. For the new application, the RTMA will be modified to reflect background error covariances consistent with wave-height fields for regional and nearshore applications. In addition, quality control modules for in situ and altimeter significant wave height have been developed and integrated into the system. The strengths and the performance of the 2D-GSI are illustrated with both in situ and satellite measurements of significant wave height in the NW Atlantic and the Gulf of Mexico. The validation of follows the typical cross-validation procedure of RTMA products, based on 10% of the observations, for a period of 15 days. The error statistics (mean, root-mean-square) of the wave-height analysis shows significant improvement, relative to the first guess.

  8. Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC mouse

    Directory of Open Access Journals (Sweden)

    Belknap John

    2010-10-01

    Full Text Available Abstract Background The current study focused on the extent genetic diversity within a species (Mus musculus affects gene co-expression network structure. To examine this issue, we have created a new mouse resource, a heterogeneous stock (HS formed from the same eight inbred strains that have been used to create the collaborative cross (CC. The eight inbred strains capture > 90% of the genetic diversity available within the species. For contrast with the HS-CC, a C57BL/6J (B6 × DBA/2J (D2 F2 intercross and the HS4, derived from crossing the B6, D2, BALB/cJ and LP/J strains, were used. Brain (striatum gene expression data were obtained using the Illumina Mouse WG 6.1 array, and the data sets were interrogated using a weighted gene co-expression network analysis (WGCNA. Results Genes reliably detected as expressed were similar in all three data sets as was the variability of expression. As measured by the WGCNA, the modular structure of the transcriptome networks was also preserved both on the basis of module assignment and from the perspective of the topological overlap maps. Details of the HS-CC gene modules are provided; essentially identical results were obtained for the HS4 and F2 modules. Gene ontology annotation of the modules revealed a significant overrepresentation in some modules for neuronal processes, e.g., central nervous system development. Integration with known protein-protein interactions data indicated significant enrichment among co-expressed genes. We also noted significant overlap with markers of central nervous system cell types (neurons, oligodendrocytes and astrocytes. Using the Allen Brain Atlas, we found evidence of spatial co-localization within the striatum for several modules. Finally, for some modules it was possible to detect an enrichment of transcription binding sites. The binding site for Wt1, which is associated with neurodegeneration, was the most significantly overrepresented. Conclusions Despite the marked

  9. Simple analytical relations for ship bow waves

    Science.gov (United States)

    Noblesse, Francis; Delhommeau, G.?Rard; Guilbaud, Michel; Hendrix, Dane; Yang, Chi

    Simple analytical relations for the bow wave generated by a ship in steady motion are given. Specifically, simple expressions that define the height of a ship bow wave, the distance between the ship stem and the crest of the bow wave, the rise of water at the stem, and the bow wave profile, explicitly and without calculations, in terms of the ship speed, draught, and waterline entrance angle, are given. Another result is a simple criterion that predicts, also directly and without calculations, when a ship in steady motion cannot generate a steady bow wave. This unsteady-flow criterion predicts that a ship with a sufficiently fine waterline, specifically with waterline entrance angle 2, may generate a steady bow wave at any speed. However, a ship with a fuller waterline (25E) can only generate a steady bow wave if the ship speed is higher than a critical speed, defined in terms of αE by a simple relation. No alternative criterion for predicting when a ship in steady motion does not generate a steady bow wave appears to exist. A simple expression for the height of an unsteady ship bow wave is also given. In spite of their remarkable simplicity, the relations for ship bow waves obtained in the study (using only rudimentary physical and mathematical considerations) are consistent with experimental measurements for a number of hull forms having non-bulbous wedge-shaped bows with small flare angle, and with the authors' measurements and observations for a rectangular flat plate towed at a yaw angle.

  10. PHOTOMETRIC ANALYSIS OF HS Aqr, EG Cep, VW LMi, AND DU Boo

    Energy Technology Data Exchange (ETDEWEB)

    Djurasevic, G.; Latkovic, O. [Astronomical Observatory, Volgina 7, 11000 Belgrade (Serbia); Bastuerk, Oe.; Y Latin-Small-Letter-Dotless-I lmaz, M. [Astronomy and Space Sciences Research and Application Center, Ankara University, TR-06837 Ahlatl Latin-Small-Letter-Dotless-I bel, Ankara (Turkey); Cal Latin-Small-Letter-Dotless-I skan, S.; Senavc Latin-Small-Letter-Dotless-I , H. V.; K Latin-Small-Letter-Dotless-I l Latin-Small-Letter-Dotless-I coglu, T.; Ekmekci, F. [Department of Astronomy and Space Sciences, Faculty of Science, Ankara University, TR-06100 Tandogan, Ankara (Turkey); Tanr Latin-Small-Letter-Dotless-I verdi, T., E-mail: olivia@aob.rs [Department of Physics, Faculty of Arts and Sciences, Nigde University, 51240 Nigde (Turkey)

    2013-03-15

    We analyze new multicolor light curves for four close late-type binaries: HS Aqr, EG Cep, VW LMi, and DU Boo, in order to determine the orbital and physical parameters of the systems and estimate the distances. The analysis is done using the modeling code of G. Djurasevic, and is based on up-to-date measurements of spectroscopic elements. All four systems have complex, asymmetric light curves that we model by including bright or dark spots on one or both components. Our findings indicate that HS Aqr and EG Cep are in semi-detached, while VW LMi and DU Boo are in overcontact configurations.

  11. The HS6000/20 development system

    International Nuclear Information System (INIS)

    Schimmel, F.

    1989-04-01

    In the actual control system of MEA, NIKHEF-K three color displays are in use for graphical representation of the accelerator status information. At the moment the quality of the color displays is bad. The HS6000 development system of the English company Syntel seems to offer a possible solution to replace these displays. In the development system software is developed which finally may run on a target module. The target module, consisting of a processor card with memory and RS232 port and a graphical card, takes care for the control of a color display. The institute has disposed of an experimental set up during two weeks in order to investigate the possibilities and limitations of the development system. The HS6000 development system runs under the OS-9 multi-user and multi-tasking operating system. The operating system takes care for a part of the necessary software to render a computer valuable. The OS-9 operating system disposes of about 60 utility commands. A feature of OS-9 is the application of modular software technique which are based upon memory modules. The interface between the user and the internal functions of the operating system is formed from the shell, the OS-9 command-interpreter code. The software, which has to run on the target module, is written with the help of the Mmacs screen editor, the draw program and the medit editor. The draw program and the medit editor form part of the EGOS ( Enhanced Graphical Output Software) packet. The EGOS packet is a multi-tasking graphical interface for the OS-9 operating system. (author). 1 fig

  12. Near-Shore Floating Wave Energy Converters

    DEFF Research Database (Denmark)

    Ruol, Piero; Zanuttigh, Barbara; Martinelli, Luca

    2011-01-01

    and transmission characteristics are approximated to functions of wave height, period and obliquity. Their order of magnitude are 20% and 80%, respectively. It is imagined that an array of DEXA is deployed in front of Marina di Ravenna beach (IT), a highly touristic site of the Adriatic Coast. Based on the CERC......Aim of this note is to analyse the possible application of a Wave Energy Converter (WEC) as a combined tool to protect the coast and harvest energy. Physical model tests are used to evaluate wave transmission past a near-shore floating WEC of the wave activated body type, named DEXA. Efficiency...

  13. Waves in separated two-phase flow

    International Nuclear Information System (INIS)

    Pols, R.M.

    1998-06-01

    This dissertation presents an integral approach to the modelling of co-current flow of liquid and gas for a class of non-linear wave problems. Typically the liquid phase and the gas phase are decoupled and the liquid is depth averaged. The resulting non-linear shallow water equations are solved to predict the behaviour of the finite amplitude waves. The integral approach is applied to the modelling of two-dimensional waves in a horizontal and slightly inclined rectangular channel, two-dimensional waves in a vertical pipe and three-dimensional waves in a horizontal tube. For flow in a horizontal or slightly inclined channel the liquid is driven by the interfacial shear from the gas phase and the surface is subject to extensive wave action. For thin liquid films the pressure in the liquid may be taken as hydrostatic and gravity acts as a restoring force on the liquid. Roll wave solutions to the non-linear shallow water equations are sought corresponding to an interfacial shear stress dependent on the liquid film height. Wave solutions are shown to exist but only for parameters within a defined range dependent on the channel inclination, interfacial roughness and linear dependence on the liquid film height of the shear stresses. Such solutions are discontinuous and are pieced together by a jump where mass and momentum are conserved. The model calculations on wave height and wave velocity are compared with experimental data. The essentially two-dimensional analysis developed for stratified horizontal flow can be extended to quasi three-dimensional flow in the case of shallow liquid depth for a circular pipe. In this case the liquid depth changes with circumferential position and consequently modifies the interfacial shear exerted on the liquid surface creating a wave spreading mechanism alongside changing the wave profile across the pipe. The wave spreading mechanism supposes a wave moving in axial direction at a velocity faster than the liquid thereby sweeping liquid

  14. HS.Register - An Audit-Trail Tool to Respond to the General Data Protection Regulation (GDPR).

    Science.gov (United States)

    Gonçalves-Ferreira, Duarte; Leite, Mariana; Santos-Pereira, Cátia; Correia, Manuel E; Antunes, Luis; Cruz-Correia, Ricardo

    2018-01-01

    Introduction The new General Data Protection Regulation (GDPR) compels health care institutions and their software providers to properly document all personal data processing and provide clear evidence that their systems are inline with the GDPR. All applications involved in personal data processing should therefore produce meaningful event logs that can later be used for the effective auditing of complex processes. Aim This paper aims to describe and evaluate HS.Register, a system created to collect and securely manage at scale audit logs and data produced by a large number of systems. Methods HS.Register creates a single audit log by collecting and aggregating all kinds of meaningful event logs and data (e.g. ActiveDirectory, syslog, log4j, web server logs, REST, SOAP and HL7 messages). It also includes specially built dashboards for easy auditing and monitoring of complex processes, crossing different systems in an integrated way, as well as providing tools for helping on the auditing and on the diagnostics of difficult problems, using a simple web application. HS.Register is currently installed at five large Portuguese Hospitals and is composed of the following open-source components: HAproxy, RabbitMQ, Elasticsearch, Logstash and Kibana. Results HS.Register currently collects and analyses an average of 93 million events per week and it is being used to document and audit HL7 communications. Discussion Auditing tools like HS.Register are likely to become mandatory in the near future to allow for traceability and detailed auditing for GDPR compliance.

  15. Tumor vessel normalization by the PI3K inhibitor HS-173 enhances drug delivery.

    Science.gov (United States)

    Kim, Soo Jung; Jung, Kyung Hee; Son, Mi Kwon; Park, Jung Hee; Yan, Hong Hua; Fang, Zhenghuan; Kang, Yeo Wool; Han, Boreum; Lim, Joo Han; Hong, Soon-Sun

    2017-09-10

    Tumor vessels are leaky and immature, which causes poor oxygen and nutrient supply to tumor vessels and results in cancer cell metastasis to distant organs. This instability of tumor blood vessels also makes it difficult for anticancer drugs to penetrate and reach tumors. Numerous tumor vessel normalization approaches have been investigated for improving drug delivery into tumors. In this study, we investigated whether phosphoinositide 3-kinase (PI3K) inhibitors are able to improve vascular structure and function over the prolonged period necessary to achieve effective vessel normalization. The PI3K inhibitors, HS-173 and BEZ235 potently suppressed tumor growth and hypoxia, and increased tumor apoptosis in animal models. PI3K inhibitors also induced a regular, flat monolayer of endothelial cells (ECs) in vessels, improving stability of vessel structure, and normalized tumor vessels by increasing vascular maturity, pericyte coverage, basement membrane thickness, and tight-junctions. These effects resulted in a decrease in tumor vessel tortuosity and vessel thinning, and improved vessel function and blood flow. The tumor vessel stabilization effect of the PI3K inhibitor HS-173 also decreased the number of metastatic lung nodules in vivo metastasis model. Furthermore, HS-173 improved the delivery of doxorubicin into the tumor region, enhancing its anticancer effects. Mechanistic studies suggested that PI3K inhibitor HS-173-induced vessel normalization reflected changes in endothelial Notch signaling. Taken together, our findings indicate that vessel normalization by PI3K inhibitors restrained tumor growth and metastasis while improving chemotherapy by enhancing drug delivery into the tumor, suggesting that HS-173 may have a therapeutic value as an enhancer or an anticancer drug. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. A study on the effect of gas flow rate on the wave characteristics in two-phase gas-liquid annular flow

    Energy Technology Data Exchange (ETDEWEB)

    Han Huawei [Faculty of Engineering and Applied Science, University of Ontario Institute of Technology, Oshawa, Ont., L1H 7K4 (Canada)]. E-mail: colin.han@uoit.ca; Zhu Zhenfeng [Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, Sask., S7N 5A9 (Canada)]. E-mail: zhz752@mail.usask.ca; Gabriel, Kamiel [University of Ontario Institute of Technology, Oshawa, Ont., L1H 7K4 (Canada)]. E-mail: kamiel.gabriel@uoit.ca

    2006-12-15

    Interfacial waves play a very important role in the mass, momentum and energy transport phenomena in annular flow. In this paper, film thickness time-trace measurements for air-water annular flow were collected in a small vertical tube using a parallel wire probe. Using the data, a typical disturbance wave shape was obtained and wave properties (e.g., width, height, speed and roughness) were presented. The liquid mass flux ranged from 100 to 200 kg/m{sup 2} s and the gas mass flux ranged from 18 to 47 kg/m{sup 2} s. Disturbance wave characteristics were defined and the effects of changing the gas flow rate on the wave spacing, wave width, wave peak height and wave base height were studied. An average velocity model for the wave and base regions has been developed to determine the wave velocity. The investigation method could be further extended to annular-mist flow which frequently occurs in boiling water reactors.

  17. A study on the effect of gas flow rate on the wave characteristics in two-phase gas-liquid annular flow

    International Nuclear Information System (INIS)

    Han Huawei; Zhu Zhenfeng; Gabriel, Kamiel

    2006-01-01

    Interfacial waves play a very important role in the mass, momentum and energy transport phenomena in annular flow. In this paper, film thickness time-trace measurements for air-water annular flow were collected in a small vertical tube using a parallel wire probe. Using the data, a typical disturbance wave shape was obtained and wave properties (e.g., width, height, speed and roughness) were presented. The liquid mass flux ranged from 100 to 200 kg/m 2 s and the gas mass flux ranged from 18 to 47 kg/m 2 s. Disturbance wave characteristics were defined and the effects of changing the gas flow rate on the wave spacing, wave width, wave peak height and wave base height were studied. An average velocity model for the wave and base regions has been developed to determine the wave velocity. The investigation method could be further extended to annular-mist flow which frequently occurs in boiling water reactors

  18. Numerical study on design for wave energy generation of a floater for energy absorption

    International Nuclear Information System (INIS)

    Li, Kui Ming; Parthasarathy, Nanjundan; Choi, Yoon Hwan; Lee, Yeon Won

    2012-01-01

    In order to design a wave energy generating system of a floater type, a 6 DOF motion technique was applied to the three Dimensional CFD analysis on a floating body and the behavior was interpreted according to the nature of the incoming waves. Waves in a tank model were generated using a single floater comparing with that of a Pelamis wave energy converter. In this paper, we focus on four variables, namely the wave height, angular velocity, diameter and length of the floater. The process was carried out in three stages and it was found that there are energy absorption differences in different parameters of wave height, length and the diameter of a floater during simulation, thus leading for the necessity of an optimal design for wave energy generation

  19. HURRICANE AND SEVERE STORM SENTINEL (HS3) FLIGHT REPORTS V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The Hurricane and Severe Storm Sentinel (HS3) Flight Reports provide information about flights flown by the WB-57 and Global Hawk aircrafts during the Hurricane and...

  20. Wave characteristics off Visakhapatnam coast during a cyclone

    Digital Repository Service at National Institute of Oceanography (India)

    SanilKumar, V.; AshokKumar, K.; Raju, N.S.N.

    CURRENT SCIENC E, VOL. 86, NO. 11, 10 JUNE 2004 *For correspondence. (e - mail: sanil@darya.nio.org) Wave characteristics off Visakhapatnam coast du r ing a cyclone V. Sanil Kumar*, K. Ashok Kumar and N. S. N. Raju Ocean Engineering Division.... Wave period The variation of average wave period ( T 02 ), period corr e- sponding to maximum wave height ( T H max ) and wave p e- riod corresponding to maximum spectral energy ( T p ) during the observation period are shown in Figure 4. Du r- i ng...

  1. Monstrous ocean waves during typhoon Krosa

    Directory of Open Access Journals (Sweden)

    P. C. Liu

    2008-06-01

    Full Text Available This paper presents a set of ocean wave time series data recorded from a discus buoy deployed near northeast Taiwan in western Pacific that was operating during the passage of Typhoon Krosa on 6 October 2007. The maximum trough-to-crest wave height was measured to be 32.3 m, which could be the largest Hmax ever recorded.

  2. Clinical significance of determination of serum hypersensitive C reactive protein (HS-CRP) levels in patients with acute coronary syndrome (ACS)

    International Nuclear Information System (INIS)

    Zhai Chunxi; Zhang Fengju; Wang Kejun

    2005-01-01

    Objective: To study the relationship between changes in serum HS-CRP levels and the status of atherosclerotic plaques in patients with ACS. Methods: Serum HS-CRP levels were measured in 35 patients with ACS at admission, 1 week and 1 month later as well as in 30 controls without recent infection. Results: HS-CRP levels in patients with ACS were significantly higher than those in the controls (P<0.01). The levels were highest at admission and fell gradually. Conclusion: HS-CRP could be a marker reflecting the status of atherosclerotic plaques in patients with ACS. (authors)

  3. Elastic Wave Control Beyond Band-Gaps: Shaping the Flow of Waves in Plates and Half-Spaces with Subwavelength Resonant Rods

    Directory of Open Access Journals (Sweden)

    Andrea Colombi

    2017-08-01

    Full Text Available In metamaterial science, local resonance and hybridization are key phenomena strongly influencing the dispersion properties; the metasurface discussed in this article created by a cluster of resonators, subwavelength rods, atop an elastic surface being an exemplar with these features. On this metasurface, band-gaps, slow or fast waves, negative refraction, and dynamic anisotropy can all be observed by exploring frequencies and wavenumbers from the Floquet–Bloch problem and by using the Brillouin zone. These extreme characteristics, when appropriately engineered, can be used to design and control the propagation of elastic waves along the metasurface. For the exemplar we consider, two parameters are easily tuned: rod height and cluster periodicity. The height is directly related to the band-gap frequency and, hence, to the slow and fast waves, while the periodicity is related to the appearance of dynamic anisotropy. Playing with these two parameters generates a gallery of metasurface designs to control the propagation of both flexural waves in plates and surface Rayleigh waves for half-spaces. Scalability with respect to the frequency and wavelength of the governing physical laws allows the application of these concepts in very different fields and over a wide range of lengthscales.

  4. Application of CFD based wave loads in aeroelastic calculations

    DEFF Research Database (Denmark)

    Schløer, Signe; Paulsen, Bo Terp; Bredmose, Henrik

    2014-01-01

    Two fully nonlinear irregular wave realizations with different significant wave heights are considered. The wave realizations are both calculated in the potential flow solver Ocean-Wave3D and in a coupled domain decomposed potential-flow CFD solver. The surface elevations of the calculated wave...... domain decomposed potentialflow CFD solver result in different dynamic forces in the tower and monopile, despite that the static forces on a fixed monopile are similar. The changes are due to differences in the force profiles and wave steepness in the two solvers. The results indicate that an accurate...

  5. Investigation of Wave Energy Converter Effects on Wave Fields: A Modeling Sensitivity Study in Monterey Bay CA.

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, Jesse D.; Grace Chang; Jason Magalen; Craig Jones

    2014-08-01

    A n indust ry standard wave modeling tool was utilized to investigate model sensitivity to input parameters and wave energy converter ( WEC ) array deploym ent scenarios. Wave propagation was investigated d ownstream of the WECs to evaluate overall near - and far - field effects of WEC arrays. The sensitivity study illustrate d that b oth wave height and near - bottom orbital velocity we re subject to the largest pote ntial variations, each decreas ed in sensitivity as transmission coefficient increase d , as number and spacing of WEC devices decrease d , and as the deployment location move d offshore. Wave direction wa s affected consistently for all parameters and wave perio d was not affected (or negligibly affected) by varying model parameters or WEC configuration .

  6. Performance Analysis of an Enhanced PRMA-HS Protocol for LEO Satellite Communication

    Institute of Scientific and Technical Information of China (English)

    ZHUO Yong-ning; YAN Shao-hu; WU Shi-qi

    2005-01-01

    The packet reservation multiple access with hindering state (PRMA-HS) is a protocol suitable for LEO satellite mobile communication. Although working well with light system payload (amount of user terminals), the protocol imposes high channel congestion on system with heavy payload, thus degrades the system's quality of service. To controlling the channel congestion, a scheme of enhanced PRMA-HS protocol is proposed, which aims to reduce the collision of voice packets by adopting a mechanism of access control. Through theoretic analysis, the system's mathematic model is presented and the packet drop probability of the scheme is deduced. To testify the performance of the scheme, a simulation is performed and the results support our analysis.

  7. How to turn gravity waves into Alfven waves and other such tricks

    International Nuclear Information System (INIS)

    Newington, Marie E; Cally, Paul S

    2011-01-01

    Recent observations of travelling gravity waves at the base of the chromosphere suggest an interplay between gravity wave propagation and magnetic field. Our aims are: to explain the observation that gravity wave flux is suppressed in magnetic regions; to understand why we see travelling waves instead of standing waves; and to see if gravity waves can undergo mode conversion and couple to Alfven waves in regions where the plasma beta is of order unity. We model gravity waves in a VAL C atmosphere, subject to a uniform magnetic field of various orientations, considering both adiabatic and radiatively damped propagation. Results indicate that in the presence of a magnetic field, the gravity wave can propagate as a travelling wave, with the magnetic field orientation playing a crucial role in determining the wave character. For the majority of magnetic field orientations, the gravity wave is reflected at low heights as a slow magneto-acoustic wave, explaining the observation of reduced flux in magnetic regions. In a highly inclined magnetic field, the gravity wave undergoes mode conversion to either field guided acoustic waves or Alfven waves. The primary effect of incorporating radiative damping is a reduction in acoustic and magnetic fluxes measured at the top of the integration region. By demonstrating the mode conversion of gravity waves to Alfven waves, this work identifies a possible pathway for energy transport from the solar surface to the upper atmosphere.

  8. Microanalysis of oligosaccharide HS203 in beagle dog plasma by postcolumn fluorescence derivatization method.

    Science.gov (United States)

    Sun, Shumeng; Zhao, Xia; Li, Guangsheng; Yu, Guangli; Xing, Xiaoxu; Zeng, Yangyang; Wu, Jian; Wang, Jianing

    2012-06-20

    A rapid and sensitive postcolumn fluorescence derivatization method was developed for microanalysis of antidiabetic oligosaccharide HS203 in beagle dog plasma. After plasma protein was removed by a simple and fast ultrafiltration method, chromatographic separation was performed on an Asahipak GS-320 HQ column with a mobile phase of 50 mmol/L phosphate buffer (pH 6.7) and acetonitrile (83/17, v/v). The column effluent was monitored by fluorescence detection at 249 nm (excitation) and 435 nm (emission) using guanidine hydrochloride as a postcolumn derivatizing reagent. A satisfactory resolution of the analyte was achieved and the limit of detection was found to be 4 ng (more sensitive than silver staining of HS203 in polyacrylamide gel electrophoresis). The method described above was successfully applied to a pharmacokinetic study of HS203 and to monitor blood glucose level simultaneously in beagle dog. It is also possible to be applied for microanalysis of other oligosaccharides in biological samples. Copyright © 2012 Elsevier Ltd. All rights reserved.

  9. Increased hsCRP is associated with higher risk of aortic valve replacement in patients with aortic stenosis

    DEFF Research Database (Denmark)

    Blyme, Adam; Nielsen, Olav W.; Asferg, Camilla

    2016-01-01

    Objective To investigate relations between inflammation and aortic valve stenosis (AS) by measuring high-sensitivity C-reactive protein, at baseline (hsCRP0) and after 1 year (hsCRP1) and exploring associations with aortic valve replacement (AVR). Design We examined 1423 patients from...... the Simvastatin and Ezetimibe in Aortic Stenosis study. Results During first year of treatment, hsCRP was reduced both in patients later receiving AVR (2.3 [0.9–4.9] to 1.8 [0.8–5.4] mg/l, p CRP1...... predicted later AVR (HR = 1.17, p CRP0 (HR = 0.96, p = 0.33), aortic valve area (AVA) and other risk factors. A higher rate of AVR was observed in the group with high hsCRP0 and an increase during the first year (AVRhighCRP0CRP1inc=47.3% versus AVRhighCRP0CRP1dec=27.5%, p

  10. Solitary impulse wave run-up and overland flow

    International Nuclear Information System (INIS)

    Fuchs, H.

    2013-04-01

    Impulse waves are generated by landslides, rockfalls or avalanches impacting a reservoir or natural lake. These long waves generated by the impulse transferred to the water body in combination with the usually short propagation distance within a lake lead to a large damage potential due to wave run-up or dam overtopping. Damages are then caused by (1) direct wave load on structures, (2) driftwood and float impact and (3) their deposits after water retreat. Major historic events occurred at Lituya Bay, Alaska, in 1958, or at the Vaiont Reservoir, Italy, in 1963. Recent events were observed at Lake Chehalis, Canada, or Lake Lucerne, Switzerland, both in 2007, or at the Lower Grindelwald proglacial lake, Switzerland, in 2009. Whereas previous VAW research aimed at the generation phase of landslide-generated impulse waves with a special focus on the wave characteristics, the current research concentrates on the opposite wave-shore interaction. A particular focus is given to the transition point from the shore slope to the horizontal plane where the orbital wave motion is transformed into a shore-parallel flow. As most literature relates only to plain wave run-up on a linearly-inclined plane and the few studies focussing on wave-induced overland flow are case studies considering only a specific bathymetry, currently no general conclusions on wave-induced overland flow can be drawn. The present study therefore intends to fill in this gap by physical modeling. Testing involved a new test-setup including a piston-type wave maker to generate solitary waves, and a smooth impermeable PVC shore of height w = 0.25 m with a connected horizontal overland flow portion. By varying the shore slope tanβ = 1/1.5, 1/2.5 and 1/5.0, the still water depth h = 0.16 - 0.24 m, and the relative wave height H/h = 0.1 -0.7, a wide range of basic parameters was covered. Overland flow depths and front velocities were measured along the shore using Ultrasonic Distance Sensors. Further, flow

  11. Experimental study of the propgation and dispersion of internal atmospheric gravity waves

    International Nuclear Information System (INIS)

    Ballard, K.A.

    1981-01-01

    Traveling ionospheric disturbances (TID's) appear as large-scale transverse waves in the F-region (150 to 1000 km altitude), with frequencies on the order of 0.005 to 0.005 cycles per minute, which propagate horizontally over hundreds or even thousands of kilometers. These disturbances have been observed by various radiowave techniques over the past thirty-five years and are now generally accepted as being the manifestation, in the ionized medium, of internal atmospheric gravity waves. A model describing the propagation of gravity waves in an isothermal atmosphere is presented here. The dispersion relation is derived from fundamental principles, and the relation between phase velocity and group velocity is examined. The effects of the Coriolis force and horizontally stratified winds on wave propagation are also analyzed. Conservation of energy in the gravity wave requires increasing amplitude with increasing altitude, inasmuch as the atmospheric density decreases with height. However, this is counteracted by dissipation of wave energy by ion drag, thermal conductivity, and viscous damping. The production of TID's (in the ionized medium) by gravity waves (in the neutral medium) is discussed in quantitative terms, and the vertical predictive function is derived. Dartmouth College has operated a three-station ionosonde network in northern New Hampshire and Vermont on an intermittent basis since 1968. Seven large TID's, found in the 1969 data, are reexamined here in an exhaustive and successful comparison with the gravity wave model. Iso-true-height contours of electron density are used to determine several pertinent TID wave parameters as a function of height

  12. Wind waves on the Black Sea: results of a hindcast study

    Science.gov (United States)

    Arkhipkin, V. S.; Gippius, F. N.; Koltermann, K. P.; Surkova, G. V.

    2014-02-01

    In this study we describe the wind waves fields on the Black Sea. The general aims of the work were the estimation of statistical wave parameters and the assessment of interannual and seasonal storm variability. The domain of this study was the entire Black Sea. Wave parameters were calculated by means of the SWAN wave model on a 5 km × 5 km rectangular grid. Initial conditions (wind speed and direction) for the period between 1948 and 2010 were derived from the NCEP/NCAR reanalysis. In our calculations the average significant wave height on the Black Sea does not exceed 0.7 m. Areas of most significant storminess are the south-western and the north-eastern corners as expressed in the spatial distribution of wave heights, wave lengths and periods. Besides that, long-term annual variations of storminess were estimated. Thus, linear trends of the annual total duration of storms and of their quantity are nearly stable over the reanalysis period. However, an intensification of storm activity is observed in the 1960s-1970s.

  13. Impact of Solutol HS 15 on the pharmacokinetic behaviour of colchicine upon intravenous administration to male Wistar rats.

    Science.gov (United States)

    Bittner, Beate; González, Roberto Carlos Bravo; Walter, Isabelle; Kapps, Martin; Huwyler, Jörg

    2003-05-01

    In the current investigation, the alkaloid colchicine was administered intravenously to male Wistar rats both as a solution in isotonic sodium chloride (NaCl 0.9%, control group) and in NaCl 0.9%:Solutol HS 15 (95:5) at 1.5 mg/kg. At predetermined time points, plasma and urine were collected from the animals and analysed for colchicine and its demethylated metabolites by LC/MS-MS. In the presence of Solutol HS 15, colchicine clearance (CI) was significantly decreased and its maximum plasma concentration (c(max)) was significantly increased as compared to the control group (CI: 15.6+/-7.0 ml/min/kg vs 34.3+/-2.3 ml/min/kg; c(max) 3055.1+/-587.4 h vs 1260.1+/-223.7 h; pSolutol HS 15 treated group (41.50+/-3.23 vs 1.17+/-0.41% of total dose; pSolutol HS 15 compared with surfactant-free incubations (overall means: 72.25+/-0.50% for FF, 0.80+/-0.02 for lambda, 0.46+/-0.04 for K(e)). In vitro, in rat hepatocytes, the clearance of colchicine was significantly reduced at 0.003% Solutol HS 15 present in the incubation medium (0.86+/-0.15 microl/min/10(-6) cells vs 1.46+/-0.06 microl/min/10(-6) cells). As colchicine exhibits a comparatively high aqueous solubility, an impact of Solutol HS 15 on the solubility of the alkaloid is very unlikely to be a reason for the observed effect. Therefore, our results indicate that the most likely reasons for the changed pharmacokinetic behaviour of colchicine in the presence of Solutol HS 15 are alterations of metabolism and/or transport as well as distribution and elimination processes. Copyright 2003 John Wiley & Sons, Ltd.

  14. Study of High Sensitive C-Reactive Protein (HS-CRP) After Cardiac Rehabilitation Program in Patients Undergoing Isolated CABG.

    Science.gov (United States)

    Johari Moghadam, Adel; Azizinejad, Saied

    2016-12-01

    Although cardiac rehabilitation is known as a tool to reduce the overall risk of cardiovascular complications, its specific role in the reduction of hs-CRP as a marker of inflammation and a proven marker of cardiovascular risk needs further investigation. The present study aims at elucidating the effects of a full course of conventional cardiac rehabilitation program for the period of eight weeks, on the levels of hs-CRP in patients who underwent isolated coronary artery bypass surgery. In this case study, 30 consecutive patients who underwent isolated coronary artery bypass surgery (isolated CABGS), and a full 8-week cardiac rehabilitation program in Tehran Heart Center, were investigated. A group of 30 similar patients, who enrolled in the same period of rehabilitation program but did not participate in practice, was considered as a control group. Serum levels of hs-CRP in both groups were measured retrospectively and in similar days before the start of rehabilitation program and at the end of it (or 8 weeks after initial registration for the control group). Levels of hs-CRP in the rehabilitation group and control group were 5.9 7.7 and 6.3 6.9 respectively before start of the program which was not statistically meaningful ( P -Value = 0.833). However, after the program, level of hs-CRP in the two tested groups changed to 2.3 5.1 and 5.7 6.1 respectively which showed a meaningful correlation ( P -Value = 0.023). These results also showed that decrease in hs-CRP level in the rehabilitated group but not in the control group was statistically meaningful (with P -Value of 0.037 and 0.0723 respectively). In patients undergoing coronary bypass surgery, participating in a full course of cardiac rehabilitation for 8 weeks has resulted in a significant reduction in hs-CRP levels as a marker of cardiovascular risk.

  15. Assessment of current effect on waves in a semi-enclosed basin

    Science.gov (United States)

    Benetazzo, A.; Carniel, S.; Sclavo, M.; Bergamasco, A.

    2012-04-01

    The wave-current interaction process in the semi-enclosed Adriatic Sea is studied using the Coupled Ocean-Atmosphere-Wave-Sediment Transport (COAWST) modeling system, which is used to exchange data fields between the ocean model ROMS (Regional Ocean Modeling System) and the wave model SWAN (Simulating WAves Nearshore). The 2-way data transfer between circulation and wave models is synchronous with ROMS providing current fields, free surface elevation, and bathymetry to SWAN. In particular, the 3-D current profiles are averaged using a formulation that integrates the near-surface velocity over a depth controlled by the spectral mean wave number. This coupling procedure is carried out up to coastal areas by means of an offline grid nesting. The parent grid covers the whole Adriatic Sea and has a horizontal resolution of 2.0 km, whereas the child grid resolution increases to 0.5 km but it is limited to the northern Adriatic Sea (Gulf of Venice), where the current effect on waves is investigated. The most frequent winds blowing on the Adriatic Sea are the so-called Bora and Sirocco which cause high waves in the Adriatic Sea, although Bora waves are generally fetch-limited. In fact, Bora winds blow orthogonal to the main basin axis (approximately aligned with the NW-SE direction), while Sirocco has large spatial scale being a southeasterly wind. For the numerical simulations, the meteorological forcings are provided by the operational meteorological model COSMO-I7, which is the Italian version of the COSMO Model, a mesoscale model developed in the framework of the COSMO Consortium. During the analysis period, the simulated wind, current and wave are compared with observations at the ISMAR oceanographic tower located off the Venice littoral. Wave heights and sea surface winds are also compared with satellite-derived data. To account for the variability of sea states during a storm, the expected maximum individual wave height in a sea storm with a given history is also

  16. High C reactive protein associated with increased pulse wave velocity among urban men with metabolic syndrome in Malaysia.

    Science.gov (United States)

    Aminuddin, Amilia; Zakaria, Zaiton; Fuad, Ahmad F; Kamsiah, Jaarin; Othman, Faizah; Das, Srijit; Kamisah, Yusof; Qodriyah, Haji S; Jubri, Zakiah; Nordin, Nor Anita M; Ngah, Wan Z

    2013-03-01

    To determine the association between carotid femoral pulse wave velocity (PWVCF); augmentation index (AI); and high-sensitivity C reactive protein (hs-CRP) with metabolic syndrome (MetS), and to determine the influence of ethnicity on PWVCF and AI, and the association between high hs-CRP and increased PWV, and AI in MetS. A cross-sectional study was conducted at Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia from September 2009 to September 2011. Three hundred and eighty men (Chinese and Malays) were recruited from the study. The PWVCF and AI were measured by Vicorder (SMT Medical, Wuerzburg, Germany). The hs-CRP level was also determined. We defined MetS using the International Diabetes Federation (IDF) and harmonized criteria. Malays had higher AI compared to the Malaysian Chinese. Patients with MetS had higher PWVCF (IDF criteria: 8.5 [8.3-8.7] versus 8.2 [8.0-8.4] m/s, p=0.03; harmonized criteria: 8.5 [8.4-8.7] versus 8.2 [8.0-8.4] m/s, p=0.007) and hs-CRP (IDF criteria: 0.9+/-2.0 versus 0.4+/-1.1 mg/L, p=0.0007; harmonized criteria: 0.8+/-1.9 versus 0.4+/-1.1 mg/L, p=0.002) compared to non-MetS. In subjects with MetS, those with high hs-CRP (>3 mg/L) had higher PWVCF. Augmentation index values were significantly higher in Malays compared with Malaysian Chinese. Metabolic syndrome was associated with increased PWVCF and hs-CRP. Patients with MetS and high hs-CRP were associated with higher PWVCF. The measurement of hs-CRP reflects the degree of subclinical vascular damage in MetS.

  17. Multiscale climate emulator of multimodal wave spectra: MUSCLE-spectra

    Science.gov (United States)

    Rueda, Ana; Hegermiller, Christie A.; Antolinez, Jose A. A.; Camus, Paula; Vitousek, Sean; Ruggiero, Peter; Barnard, Patrick L.; Erikson, Li H.; Tomás, Antonio; Mendez, Fernando J.

    2017-02-01

    Characterization of multimodal directional wave spectra is important for many offshore and coastal applications, such as marine forecasting, coastal hazard assessment, and design of offshore wave energy farms and coastal structures. However, the multivariate and multiscale nature of wave climate variability makes this complex problem tractable using computationally expensive numerical models. So far, the skill of statistical-downscaling model-based parametric (unimodal) wave conditions is limited in large ocean basins such as the Pacific. The recent availability of long-term directional spectral data from buoys and wave hindcast models allows for development of stochastic models that include multimodal sea-state parameters. This work introduces a statistical downscaling framework based on weather types to predict multimodal wave spectra (e.g., significant wave height, mean wave period, and mean wave direction from different storm systems, including sea and swells) from large-scale atmospheric pressure fields. For each weather type, variables of interest are modeled using the categorical distribution for the sea-state type, the Generalized Extreme Value (GEV) distribution for wave height and wave period, a multivariate Gaussian copula for the interdependence between variables, and a Markov chain model for the chronology of daily weather types. We apply the model to the southern California coast, where local seas and swells from both the Northern and Southern Hemispheres contribute to the multimodal wave spectrum. This work allows attribution of particular extreme multimodal wave events to specific atmospheric conditions, expanding knowledge of time-dependent, climate-driven offshore and coastal sea-state conditions that have a significant influence on local nearshore processes, coastal morphology, and flood hazards.

  18. Spatial evolution equation of wind wave growth

    Institute of Scientific and Technical Information of China (English)

    WANG; Wei; (王; 伟); SUN; Fu; (孙; 孚); DAI; Dejun; (戴德君)

    2003-01-01

    Based on the dynamic essence of air-sea interactions, a feedback type of spatial evolution equation is suggested to match reasonably the growing process of wind waves. This simple equation involving the dominant factors of wind wave growth is able to explain the transfer of energy from high to low frequencies without introducing the concept of nonlinear wave-wave interactions, and the results agree well with observations. The rate of wave height growth derived in this dissertation is applicable to both laboratory and open sea, which solidifies the physical basis of using laboratory experiments to investigate the generation of wind waves. Thus the proposed spatial evolution equation provides a new approach for the research on dynamic mechanism of air-sea interactions and wind wave prediction.

  19. Clinical significance of measurement of serum hs-CRP, TNF-α and M-CSF levels after treatment in patients with periodontitis

    International Nuclear Information System (INIS)

    Zhang Yunming

    2007-01-01

    Objective: To explore the significance of changes of serum hs-CRP, TNF-α and M-CSF levels after treatment in patients with periodontitis. Methods: Serum TNF-α, M-CSF (with RIA), hs-CRP (with immuneturbitity method) levels were determined in 38 patients with periodontitis both before and after treatment as well as in 35 controls. Results: Before treatment, the serum hs-CRP, TNF-α and M-CSF levels were significantly higher in the patients than those in controls (P 0.05). Conclusion: Detection of serum hs-CRP, TNF-α and M-CSF levels might reflect the progress of disease in patients with periodontitis. (authors)

  20. Long-term statistics of extreme tsunami height at Crescent City

    Science.gov (United States)

    Dong, Sheng; Zhai, Jinjin; Tao, Shanshan

    2017-06-01

    Historically, Crescent City is one of the most vulnerable communities impacted by tsunamis along the west coast of the United States, largely attributed to its offshore geography. Trans-ocean tsunamis usually produce large wave runup at Crescent Harbor resulting in catastrophic damages, property loss and human death. How to determine the return values of tsunami height using relatively short-term observation data is of great significance to assess the tsunami hazards and improve engineering design along the coast of Crescent City. In the present study, the extreme tsunami heights observed along the coast of Crescent City from 1938 to 2015 are fitted using six different probabilistic distributions, namely, the Gumbel distribution, the Weibull distribution, the maximum entropy distribution, the lognormal distribution, the generalized extreme value distribution and the generalized Pareto distribution. The maximum likelihood method is applied to estimate the parameters of all above distributions. Both Kolmogorov-Smirnov test and root mean square error method are utilized for goodness-of-fit test and the better fitting distribution is selected. Assuming that the occurrence frequency of tsunami in each year follows the Poisson distribution, the Poisson compound extreme value distribution can be used to fit the annual maximum tsunami amplitude, and then the point and interval estimations of return tsunami heights are calculated for structural design. The results show that the Poisson compound extreme value distribution fits tsunami heights very well and is suitable to determine the return tsunami heights for coastal disaster prevention.

  1. Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated In Vitro in cell cultures.

    OpenAIRE

    Shubber, Saif; Vllasaliu, Driton; Rauch, Cyril; Jordan, Faron; Illum, Lisbeth; Stolnik, Snjezana

    2015-01-01

    Purpose CriticalSorb?, with the principal component Solutol? HS15, is a novel mucosal drug delivery system demonstrated to improve the bioavailability of selected biotherapeutics. The intention of this study is to elucidate mechanism(s) responsible for the enhancement of trans-mucosal absorption of biological drugs by Solutol? HS15. Methods Micelle size and CMC of Solutol? HS15 were determined in biologically relevant media. Polarised airway Calu-3 cell layers were used to measure the permeab...

  2. The response of the southwest Western Australian wave climate to Indian Ocean climate variability

    Science.gov (United States)

    Wandres, Moritz; Pattiaratchi, Charitha; Hetzel, Yasha; Wijeratne, E. M. S.

    2018-03-01

    Knowledge of regional wave climates is critical for coastal planning, management, and protection. In order to develop a regional wave climate, it is important to understand the atmospheric systems responsible for wave generation. This study examines the variability of the southwest Western Australian (SWWA) shelf and nearshore wind wave climate and its relationship to southern hemisphere climate variability represented by various atmospheric indices: the southern oscillation index (SOI), the Southern Annular Mode (SAM), the Indian Ocean Dipole Mode Index (DMI), the Indian Ocean Subtropical Dipole (IOSD), the latitudinal position of the subtropical high-pressure ridge (STRP), and the corresponding intensity of the subtropical ridge (STRI). A 21-year wave hindcast (1994-2014) of the SWWA continental shelf was created using the third generation wave model Simulating WAves Nearshore (SWAN), to analyse the seasonal and inter-annual wave climate variability and its relationship to the atmospheric regime. Strong relationships between wave heights and the STRP and the STRI, a moderate correlation between the wave climate and the SAM, and no significant correlation between SOI, DMI, and IOSD and the wave climate were found. Strong spatial, seasonal, and inter-annual variability, as well as seasonal longer-term trends in the mean wave climate were studied and linked to the latitudinal changes in the subtropical high-pressure ridge and the Southern Ocean storm belt. As the Southern Ocean storm belt and the subtropical high-pressure ridge shifted southward (northward) wave heights on the SWWA shelf region decreased (increased). The wave height anomalies appear to be driven by the same atmospheric conditions that influence rainfall variability in SWWA.

  3. Wavelet Transform Based Higher Order Statistical Analysis of Wind and Wave Time Histories

    Science.gov (United States)

    Habib Huseni, Gulamhusenwala; Balaji, Ramakrishnan

    2017-10-01

    Wind, blowing on the surface of the ocean, imparts the energy to generate the waves. Understanding the wind-wave interactions is essential for an oceanographer. This study involves higher order spectral analyses of wind speeds and significant wave height time histories, extracted from European Centre for Medium-Range Weather Forecast database at an offshore location off Mumbai coast, through continuous wavelet transform. The time histories were divided by the seasons; pre-monsoon, monsoon, post-monsoon and winter and the analysis were carried out to the individual data sets, to assess the effect of various seasons on the wind-wave interactions. The analysis revealed that the frequency coupling of wind speeds and wave heights of various seasons. The details of data, analysing technique and results are presented in this paper.

  4. Analysis of relationship between blood lipid metabolism levels and hs-CRP levels in patients with chronic obstructive pulmonary disease

    International Nuclear Information System (INIS)

    You Fengjian

    2011-01-01

    Objective: To study the relationship between blood lipid metabolism levels and hs-CRP levels in the patients with chronic obstructive pulmonary disease. Methods: The levels of plasma blood lipid (with biochemistry) and serum hs-CRP(with high-sensitive immuno turbidimetry) were determined in 96 patients with chronic obstructive pulmonary disease as well as 68 normal controls. Results: The plasma blood lipid levels in 96 patients with chronic obstructive pulmonary disease were significantly lower than those in 68 controls, plasma TC and LDL-C levels were not much difference (P>0.05), plasma HDL-C level was significantly difference (P<0.05), but TG and Lp (a) levels were very prominently difference (P<0.01). And the plasma hs-CRP level was significantly increased also (P<0.01). The close relationship was between blood lipid and hs-CRP levels. Conclusion: The study of relationship between blood lipid levels and hs-CRP levels in patients with COPD was helpful for understand the disease process as well as possible mechanisms. (authors)

  5. Experimental Study on the Langlee Wave Energy Converter

    DEFF Research Database (Denmark)

    Pecher, Arthur; Kofoed, Jens Peter; Weisz, A.

    This report presents the results of an experimental study of the wave energy converting abilities of the Langlee wave energy converter (WEC). It focused mainly on evaluating the power generating capabilities of the device, including investigations of the following issues: Scaling ratiosPTO loadingWave...... height and wave period dependencyOblique incoming waves and directional spreading of waves (3D waves)Damping platesMooring forces and fixed structure setupPitch, surge and heave motion During the study the model supplied by the client (Langlee Wave Power AS) has been heavily instrumented - up to 23...... different instruments was deployed to measure and record data. Tests were performed at scales of 1:30 and 1:20 based on the realized reference wave states....

  6. Study and Evaluation of Ultrasound System for Detecting the Height of Corn Canopy

    Directory of Open Access Journals (Sweden)

    T Mesri Gundoshmian

    2017-10-01

    Full Text Available Introduction Growth of population, deficiency of resources, environmental hazards, fast spatial science progress and relevant subjects have resulted in significant effects of enhanced accuracy and modern technologies in agricultural technology and management methods. One of the modern technologies’ utilities in production and nondestructive tests is determination of product characteristics (such as product height, using electronic sensors at different stages of plant growth. In recent years, electric sensors improved widely in farm science. Regarding to wide performance of sensors, from simple sensors such as thermo, light and moisture sensors, to complex ones such as GPS and lidar, also the ability of electronic sensors to exact identification and measurement of special farm properties, makes these sensors to an important part of precision agriculture. The subject of this study is to identify and measure the height of the product using ultrasonic technology to automate control of breeding and harvesting operations. Suitable price and noise and dust resistance of ultrasonic sensor, make it an attractive subject in biosystem industries and farm operations. Materials and Methods Plant height measurement Ultrasonic sensor includes an ultrasonic transmitter and receiver with more than 20 kHz frequency. As other waves, ultrasonic waves diffuse constantly from a source by mechanical distracting in a gas, liquid or solid environment. The distance between sensor and object is a function of the wave passing time from generation point to receive point. Plant height calculated by estimating this distance and minus it from sensor height. The sensor used in this research had a diffuse angle of 40 degrees to center axis of source. The sensor ability to height measurement depends on leaves angle, leaves surface, plant aggregation in area and plant height. Leaves angle is the most important factor in recognization ability of ultrasonic sensor. Electronic

  7. Concordant preferences for actual height and facial cues to height

    OpenAIRE

    Re, Daniel Edward; Perrett, David I.

    2012-01-01

    Physical height has a well-documented effect on human mate preferences. In general, both sexes prefer opposite-sex romantic relationships in which the man is taller than the woman, while individual preferences for height are affected by a person’s own height. Research in human mate choice has demonstrated that attraction to facial characteristics, such as facial adiposity, may reflect references for body characteristics. Here, we tested preferences for facial cues to height. In general, incre...

  8. Effect of the additives on clouding behavior and thermodynamics of coenzyme Q10-Kolliphor HS15 micelle aqueous solutions

    Science.gov (United States)

    Hu, Li; Zhang, Jing; Zhu, Chao; Pan, Hong-chun; Liu, Hong

    2017-11-01

    Herein we investigate the effect of different additives (electrolytes, amino acids, PEG, and sugars) on the cloud points (CP) of coenzyme Q10 (CoQ10) - Kolliphor HS15 (HS15) micelle aqueous solutions. The CP values were decreased with the increase of electrolytes and sugars, following: CPAl3+ reduced the CP. A depression of CP for CoQ10-HS15 micelle solution with PEG was molecular weight of PEG dependent. The significant thermodynamic parameters were also evaluated and discussed.

  9. CoCoRaHS: A Community Science Program Providing Valuable Precipitation Data to Guide Decision Making

    Science.gov (United States)

    Robinson, D. A.; Doesken, N.

    2017-12-01

    CoCoRaHS is an acronym for the Community Collaborative Rain, Hail and Snow Network. It is long-running, community-based network of volunteers working together to measure and map precipitation (rain, hail and snow). Precipitation is an ideal element for public engagement because it affects everyone, it is so variable in time and space and it impacts so many things. By using a standard precipitation gauge, stressing training and education, utilizing an interactive website, and having observations undergo quality assurance, the CoCoRaHS program provides high-quality data for natural resource, education and research applications. The program currently operates in all states, Canada and the Bahamas. It originated with the Colorado Climate Center at Colorado State University in 1998 due in part to the Fort Collins flood a year prior. Upwards of 12,000 observers submit observations each day. Observations meet federal guidelines and are archived at the U.S. National Centers for Environmental Information. Because of excellent spatial coverage, data quality, practical relevance, and accessibility, CoCoRaHS observations are used by a wide variety of organizations and individuals. The U.S. National Weather Service, hydrologists, emergency managers, city utilities (water supply, storm water), insurance adjusters, the U.S. Department of Agriculture, engineers, mosquito control commissions, ranchers and farmers, outdoor and recreation interests, teachers and students are just some examples of those who use CoCoRaHS data in making well-informed, meaningful decisions. Some examples of community applications and the science utility of CoCoRaHS observations include storm warnings, water supply and demand forecasts, disaster declarations (drought, winter storm, etc.), drought and food production assessments, calibration/validation of remote sensing, infrastructure evaluation and potential redesign (ice and snow loading, bridge, storm and sewer design), recreation planning, and

  10. Forecasting ocean wave energy: A Comparison of the ECMWF wave model with time series methods

    DEFF Research Database (Denmark)

    Reikard, Gordon; Pinson, Pierre; Bidlot, Jean

    2011-01-01

    Recently, the technology has been developed to make wave farms commercially viable. Since electricity is perishable, utilities will be interested in forecasting ocean wave energy. The horizons involved in short-term management of power grids range from as little as a few hours to as long as several...... days. In selecting a method, the forecaster has a choice between physics-based models and statistical techniques. A further idea is to combine both types of models. This paper analyzes the forecasting properties of a well-known physics-based model, the European Center for Medium-Range Weather Forecasts...... (ECMWF) Wave Model, and two statistical techniques, time-varying parameter regressions and neural networks. Thirteen data sets at locations in the Atlantic and Pacific Oceans and the Gulf of Mexico are tested. The quantities to be predicted are the significant wave height, the wave period, and the wave...

  11. Clinical Significance of Determination of the Serum Levels of NT-proBNP and hs-CRP in Patients with Acute Coronary Syndrome

    International Nuclear Information System (INIS)

    Zheng Zhaojun; Zheng Jing; Sun Weili; Yuan Yuan; Tao Jian; Li Weipeng

    2010-01-01

    To explore the clinical significance the serum levels of N-Terminal proB-Type natriuretic peptide (NT-proBNP) and high-sensitivity C-reactive protein (hs-CRP) in patients with acute coronary syndrome,the serum levels of NT-proBNP and hs-CRP in patients and normal controls were determined by ECi Immunity Analyzer and radioimmunoassay respectively. The results showed that the serum levels of NT-proBNP and hs-CRP in patients with acute coronary syndrome were significantly higher than that of controls (P<0.05). The diagnostic specificity for acute coronary syndrome was 100% by combined detection of NT-proBNP and hs-CRP. The results suggest that the combined detection of serum NT-proBNP and hs-CRP levels are very important to evaluate heart function in patients with acute coronary syndrome. (authors)

  12. Correlation of Serum Levels of Vitronectin, Malondialdehyde and Hs-CRP With Disease Severity in Coronary Artery Disease

    Directory of Open Access Journals (Sweden)

    Alireza Yaghoubi

    2015-09-01

    Conclusion: The association and correlation between VN, MDA and hs-CRP indicate their involvement in the atherosclerosis process that may lead to progression of CAD. Also, these findings suggested that serum levels of VN, MDA and hs-CRP can help as diagnostic and monitoring markers in CAD patients and as markers of disease severity.

  13. Finite energy wave signals of extremal amplitude in the spatial NLS-dynamics

    NARCIS (Netherlands)

    van Groesen, Embrecht W.C.; Andonowati, A.

    2006-01-01

    With the aim to find extremal properties of extreme waves, we consider waves of maximal crest (and wave) height in the model of the spatial NLS-dynamics. Using the two motion invariants momentum and Hamiltonian as constraints, we show that so-called cornered solitons provide the maximal crest

  14. Rogue waves in a water tank: Experiments and modeling

    Science.gov (United States)

    Lechuga, Antonio

    2013-04-01

    Recently many rogue waves have been reported as the main cause of ship incidents on the sea. One of the main characteristics of rogue waves is its elusiveness: they present unexpectedly and disappear in the same wave. Some authors (Zakharov and al.2010) are attempting to find the probability of their appearances apart from studyingthe mechanism of the formation. As an effort on this topic we tried the generation of rogue waves in a water wave tank using a symmetric spectrum(Akhmediev et al. 2011) as input on the wave maker. The produced waves were clearly rogue waves with a rate (maximum wave height/ Significant wave height) of 2.33 and a kurtosis of 4.77 (Janssen 2003, Onorato 2006). These results were already presented (Lechuga 2012). Similar waves (in pattern aspect, but without being extreme waves) were described as crossing waves in a water tank(Shemer and Lichter1988). To go on further the next step has been to apply a theoretical model to the envelope of these waves. After some considerations the best model has been an analogue of the Ginzburg-Landau equation. This apparently amazing result is easily explained: We know that the Ginzburg-Landau model is related to some regular structures on the surface of a liquid and also in plasmas, electric and magnetic fields and other media. Another important characteristic of the model is that their solutions are invariants with respectto the translation group. The main aim of this presentation is to extract conclusions of the model and the comparison with the measured waves in the water tank.The nonlinear structure of waves and their regularity make suitable the use of the Ginzburg-Landau model to the envelope of generated waves in the tank,so giving us a powerful tool to cope with the results of our experiment.

  15. Characterization of the Deep Water Surface Wave Variability in the California Current Region

    Science.gov (United States)

    Villas Bôas, Ana B.; Gille, Sarah T.; Mazloff, Matthew R.; Cornuelle, Bruce D.

    2017-11-01

    Surface waves are crucial for the dynamics of the upper ocean not only because they mediate exchanges of momentum, heat, energy, and gases between the ocean and the atmosphere, but also because they determine the sea state. The surface wave field in a given region is set by the combination of local and remote forcing. The present work characterizes the seasonal variability of the deep water surface wave field in the California Current region, as retrieved from over two decades of satellite altimetry data combined with wave buoys and wave model hindcast (WaveWatch III). In particular, the extent to which the local wind modulates the variability of the significant wave height, peak period, and peak direction is assessed. During spring/summer, regional-scale wind events of up to 10 m/s are the dominant forcing for waves off the California coast, leading to relatively short-period waves (8-10 s) that come predominantly from the north-northwest. The wave climatology throughout the California Current region shows average significant wave heights exceeding 2 m during most of the year, which may have implications for the planning and retrieval methods of the Surface Water and Ocean Topography (SWOT) satellite mission.

  16. Love and fear of heights: the pathophysiology and psychology of height imbalance.

    Science.gov (United States)

    Salassa, John R; Zapala, David A

    2009-01-01

    Individual psychological responses to heights vary on a continuum from acrophobia to height intolerance, height tolerance, and height enjoyment. This paper reviews the English literature and summarizes the physiologic and psychological factors that generate different responses to heights while standing still in a static or motionless environment. Perceptual cues to height arise from vision. Normal postural sway of 2 cm for peripheral objects within 3 m increases as eye-object distance increases. Postural sway >10 cm can result in a fall. A minimum of 20 minutes of peripheral retinal arc is required to detect motion. Trigonometry dictates that a 20-minute peripheral retinal arch can no longer be achieved in a standing position at an eye-object distance of >20 m. At this distance, visual cues conflict with somatosensory and vestibular inputs, resulting in variable degrees of imbalance. Co-occurring deficits in the visual, vestibular, and somatosensory systems can significantly increase height imbalance. An individual's psychological makeup, influenced by learned and genetic factors, can influence reactions to height imbalance. Enhancing peripheral vision and vestibular, proprioceptive, and haptic functions may improve height imbalance. Psychotherapy may improve the troubling subjective sensations to heights.

  17. Modeled changes in extreme wave climates of the tropical Pacific over the 21st century: Implications for U.S. and U.S.-Affiliated atoll islands

    Science.gov (United States)

    Shope, J.B.; Storlazzi, Curt; Erikson, Li H.; Hegermiller, C.A.

    2015-01-01

    Wave heights, periods, and directions were forecast for 2081–2100 using output from four coupled atmosphere–ocean global climate models for representative concentration pathway scenarios RCP4.5 and RCP8.5. Global climate model wind fields were used to drive the global WAVEWATCH-III wave model to generate hourly time-series of bulk wave parameters for 25 islands in the mid to western tropical Pacific. December–February 95th percentile extreme significant wave heights under both climate scenarios decreased by 2100 compared to 1976–2010 historical values. Trends under both scenarios were similar, with the higher-emission RCP8.5 scenario displaying a greater decrease in extreme significant wave heights than where emissions are reduced in the RCP4.5 scenario. Central equatorial Pacific Islands displayed the greatest departure from historical values; significant wave heights decreased there by as much as 0.32 m during December–February and associated wave directions rotated approximately 30° clockwise during June–August compared to hindcast data.

  18. Large Scale Model Test Investigation on Wave Run-Up in Irregular Waves at Slender Piles

    DEFF Research Database (Denmark)

    Ramirez, Jorge Robert Rodriguez; Frigaard, Peter; Andersen, Thomas Lykke

    2013-01-01

    An experimental large scale study on wave run-up generated loads on entrance platforms for offshore wind turbines was performed. The experiments were performed at GrosserWellenkanal (GWK), Forschungszentrum Küste (FZK) in Hannover, Germany. The present paper deals with the run-up heights determin...

  19. Comparable Analysis of the Distribution Functions of Runup Heights of the 1896, 1933 and 2011 Japanese Tsunamis in the Sanriku Area

    Science.gov (United States)

    Choi, B. H.; Min, B. I.; Yoshinobu, T.; Kim, K. O.; Pelinovsky, E.

    2012-04-01

    Data from a field survey of the 2011 tsunami in the Sanriku area of Japan is presented and used to plot the distribution function of runup heights along the coast. It is shown that the distribution function can be approximated using a theoretical log-normal curve [Choi et al, 2002]. The characteristics of the distribution functions derived from the runup-heights data obtained during the 2011 event are compared with data from two previous gigantic tsunamis (1896 and 1933) that occurred in almost the same region. The number of observations during the last tsunami is very large (more than 5,247), which provides an opportunity to revise the conception of the distribution of tsunami wave heights and the relationship between statistical characteristics and number of observations suggested by Kajiura [1983]. The distribution function of the 2011 event demonstrates the sensitivity to the number of observation points (many of them cannot be considered independent measurements) and can be used to determine the characteristic scale of the coast, which corresponds to the statistical independence of observed wave heights.

  20. Comparable analysis of the distribution functions of runup heights of the 1896, 1933 and 2011 Japanese Tsunamis in the Sanriku area

    Directory of Open Access Journals (Sweden)

    B. H. Choi

    2012-05-01

    Full Text Available Data from a field survey of the 2011 Tohoku-oki tsunami in the Sanriku area of Japan is used to plot the distribution function of runup heights along the coast. It is shown that the distribution function can be approximated by a theoretical log-normal curve. The characteristics of the distribution functions of the 2011 event are compared with data from two previous catastrophic tsunamis (1896 and 1933 that occurred in almost the same region. The number of observations during the last tsunami is very large, which provides an opportunity to revise the conception of the distribution of tsunami wave heights and the relationship between statistical characteristics and the number of observed runup heights suggested by Kajiura (1983 based on a small amount of data on previous tsunamis. The distribution function of the 2011 event demonstrates the sensitivity to the number of measurements (many of them cannot be considered independent measurements and can be used to determine the characteristic scale of the coast, which corresponds to the statistical independence of observed wave heights.

  1. Solitary impulse wave run-up and overland flow

    Energy Technology Data Exchange (ETDEWEB)

    Fuchs, H.

    2013-04-15

    Impulse waves are generated by landslides, rockfalls or avalanches impacting a reservoir or natural lake. These long waves generated by the impulse transferred to the water body in combination with the usually short propagation distance within a lake lead to a large damage potential due to wave run-up or dam overtopping. Damages are then caused by (1) direct wave load on structures, (2) driftwood and float impact and (3) their deposits after water retreat. Major historic events occurred at Lituya Bay, Alaska, in 1958, or at the Vaiont Reservoir, Italy, in 1963. Recent events were observed at Lake Chehalis, Canada, or Lake Lucerne, Switzerland, both in 2007, or at the Lower Grindelwald proglacial lake, Switzerland, in 2009. Whereas previous VAW research aimed at the generation phase of landslide-generated impulse waves with a special focus on the wave characteristics, the current research concentrates on the opposite wave-shore interaction. A particular focus is given to the transition point from the shore slope to the horizontal plane where the orbital wave motion is transformed into a shore-parallel flow. As most literature relates only to plain wave run-up on a linearly-inclined plane and the few studies focussing on wave-induced overland flow are case studies considering only a specific bathymetry, currently no general conclusions on wave-induced overland flow can be drawn. The present study therefore intends to fill in this gap by physical modeling. Testing involved a new test-setup including a piston-type wave maker to generate solitary waves, and a smooth impermeable PVC shore of height w = 0.25 m with a connected horizontal overland flow portion. By varying the shore slope tanβ = 1/1.5, 1/2.5 and 1/5.0, the still water depth h = 0.16 - 0.24 m, and the relative wave height H/h = 0.1 -0.7, a wide range of basic parameters was covered. Overland flow depths and front velocities were measured along the shore using Ultrasonic Distance Sensors. Further, flow

  2. Clinical application of combined detection of serum hs-CRP, GMP-140 and cTnI in patients with coronary heart diseases

    International Nuclear Information System (INIS)

    Qin Jibao; Wu Zhaozeng

    2010-01-01

    Objective: To explore the clinical significance of changes of serum hs-CRP, GMP-140 and cTnI levels in patients with coronary heart diseases. Methods: Serum GMP-140 (with RIA), cTnI (with ELISA) and hs-CRP (with immuno turbidity method) levels were determined in 91 patients with coronary heart diseases (42 SAP, 34UAP, 15AMI) and 35 controls. Results: Serum hs-CRP, GMP-140, cTnI levels in patients with coronary heart diseases were significantly higher than those in controls (P <0.01). Among the patients with of coronary heart diseases, the magnitude of changes of the levels of serum hs-CRP, GMP-140 and cTnI levels in AMI and UAP groups were significantly larger than those in SAP group (P < 0.05). Serum hs-CRP levels were positively correlated with serum GMP-140 and cTnI levels (r = 0.6214, 0.6023, P < 0.01). Conclusion: Serum hs-CRP, GMP140 and cTnI levels were closely related to the diseases process of coronary heart diseases and were of great clinical importance for assessment of the disease and outcome prediction. (authors)

  3. Application of Soft Computing Tools for Wave Prediction at Specific Locations in the Arabian Sea Using Moored Buoy Observations

    Directory of Open Access Journals (Sweden)

    J. Vimala

    2012-12-01

    Full Text Available The knowledge of design and operational values of significant wave heights is perhaps the single most important input needed in ocean engineering studies. Conventionally such information is obtained using classical statistical analysis and stochastic methods. As the causative variables are innumerable and underlying physics is too complicated, the results obtained from the numerical models may not always be very satisfactory. Soft computing tools like Artificial Neural Network (ANN and Adaptive Network based Fuzzy Inference System (ANFIS may therefore be useful to predict significant wave heights in some situations. The study is aimed at forecasting of significant wave height values in real time over a period of 24hrs at certain locations in Indian seas using the models of ANN and ANFIS. The data for the work were collected by National Institute of Ocean Technology, Chennai. It was found that the predictions of wave heights can be done by both methods with equal efficiency and satisfaction.

  4. Correlation of Progranulin, Granulin, Adiponectin and Vaspin with Metaflammation (hs-CRP in Indonesian Obese Men

    Directory of Open Access Journals (Sweden)

    Rosalia E Napitupulu

    2013-08-01

    Full Text Available BACKGROUND: Obesity is closely related to chronic, low grade systemic inflammation (metaflammation and it leads to further metabolic complications such as hypertension, atherosclerosis, and type 2 diabetes due to the adipocytokine imbalance. This study was carried out to assess the correlation between progranulin, granulin, adiponectin and visceral adipose tissue-derived serine protease inhibitor (Vaspin with metaflammation (high sensitivity C-reactive protein (hs-CRP in centrally obese men. METHODS: This study was observational with a cross sectional design involving 60 men aged 30-60 years, consisted of 43 obese men (waist circumference (WC ≥90 cm and 13 non obese men (WC 105 cm. CONCLUSIONS: We found metaflammation (hs-CRP was significantly correlated with Vaspin, but not with progranulin, granulin and adiponectin, in obese men. We suggest the possibility of a dynamic expression of adipokines related to WC that are subjected to adipocytes hypertrophy-hyperplasia phenomenon. KEYWORDS: progranulin, granulin, adiponectin, Vaspin, hs-CRP, metaflammation, central obesity.

  5. Phase mixing of Alfvén waves in axisymmetric non-reflective magnetic plasma configurations

    Science.gov (United States)

    Petrukhin, N. S.; Ruderman, M. S.; Shurgalina, E. G.

    2018-02-01

    We study damping of phase-mixed Alfvén waves propagating in non-reflective axisymmetric magnetic plasma configurations. We derive the general equation describing the attenuation of the Alfvén wave amplitude. Then we applied the general theory to a particular case with the exponentially divergent magnetic field lines. The condition that the configuration is non-reflective determines the variation of the plasma density along the magnetic field lines. The density profiles exponentially decreasing with the height are not among non-reflective density profiles. However, we managed to find non-reflective profiles that fairly well approximate exponentially decreasing density. We calculate the variation of the total wave energy flux with the height for various values of shear viscosity. We found that to have a substantial amount of wave energy dissipated at the lower corona, one needs to increase shear viscosity by seven orders of magnitude in comparison with the value given by the classical plasma theory. An important result that we obtained is that the efficiency of the wave damping strongly depends on the density variation with the height. The stronger the density decrease, the weaker the wave damping is. On the basis of this result, we suggested a physical explanation of the phenomenon of the enhanced wave damping in equilibrium configurations with exponentially diverging magnetic field lines.

  6. Clinical significance of changes of serum hs-CRP, IL-6 and TNF-α levels after treatment in patients with polycystic ovary syndrome

    International Nuclear Information System (INIS)

    Yang Wen; Wang Ying

    2010-01-01

    Objective: To explore the clinical significance of changes of serum hs-CRP, IL-6 and TNF-α levels in patients with polycystic ovary syndrome. Methods: Serum hs-CRP (with immuno turbidity method), IL-6, TNF-α (with RIA) levels were determined in 31 patients with polycystic ovary syndrome both before and after six, month's treatment as well as 35 controls. Results: Before treatment, the serum hs-CRP, IL-6 and TNF-α levels in the 31 patients with polycystic ovary syndrome were significantly higher than those in controls (P 0.05). Serum hs-CRP levels were positive correlate with serum IL-6, TNF-α levels (r=0.6014, 0.5982, P<0.01). Conclusion: Serum hs-CRP, IL-6 and TNF-α levels were correlated to the development of polycystic ovary syndrome (PCOS). (authors)

  7. Comparison of ERA-Interim waves with buoy data in the eastern Arabian Sea during high waves

    Digital Repository Service at National Institute of Oceanography (India)

    Shanas, P.R.; SanilKumar, V.

    at two locations in eastern Arabian Sea One location is a deep water location and another one is a shallow water location The comparison of significant wave height (SWH) between ERA dataset and buoy data at both the locations shows good correlation...

  8. Metamaterial Absorber for Electromagnetic Waves in Periodic Water Droplets.

    Science.gov (United States)

    Yoo, Young Joon; Ju, Sanghyun; Park, Sang Yoon; Ju Kim, Young; Bong, Jihye; Lim, Taekyung; Kim, Ki Won; Rhee, Joo Yull; Lee, YoungPak

    2015-09-10

    Perfect metamaterial absorber (PMA) can intercept electromagnetic wave harmful for body in Wi-Fi, cell phones and home appliances that we are daily using and provide stealth function that military fighter, tank and warship can avoid radar detection. We reported new concept of water droplet-based PMA absorbing perfectly electromagnetic wave with water, an eco-friendly material which is very plentiful on the earth. If arranging water droplets with particular height and diameter on material surface through the wettability of material surface, meta-properties absorbing electromagnetic wave perfectly in GHz wide-band were shown. It was possible to control absorption ratio and absorption wavelength band of electromagnetic wave according to the shape of water droplet-height and diameter- and apply to various flexible and/or transparent substrates such as plastic, glass and paper. In addition, this research examined how electromagnetic wave can be well absorbed in water droplets with low electrical conductivity unlike metal-based metamaterials inquiring highly electrical conductivity. Those results are judged to lead broad applications to variously civilian and military products in the future by providing perfect absorber of broadband in all products including transparent and bendable materials.

  9. Optimal Tilt Angle and Orientation of Photovoltaic Modules Using HS Algorithm in Different Climates of China

    Directory of Open Access Journals (Sweden)

    Mian Guo

    2017-10-01

    Full Text Available Solar energy technologies play an important role in shaping a sustainable energy future, and generating clean, renewable, and widely distributed energy sources. This paper determines the optimum tilt angle and optimum azimuth angle of photovoltaic (PV panels, employing the harmony search (HS meta-heuristic algorithm. In this study, the ergodic method is first conducted to obtain the optimum tilt angle and the optimum azimuth angle in several cities of China based on the model of Julian dating. Next, the HS algorithm is applied to search for the optimum solution. The purpose of this research is to maximize the extraterrestrial radiation on the collector surface for a specific period. The sun’s position is predicted by the proposed model at different times, and then solar radiation is obtained on various inclined planes with different orientations in each city. The performance of the HS method is compared with that of the ergodic method and other optimization algorithms. The results demonstrate that the tilt angle should be changed once a month, and the best orientation is usually due south in the selected cities. In addition, the HS algorithm is a practical and reliable alternative for estimating the optimum tilt angle and optimum azimuth angle of PV panels.

  10. Extreme coastal erosion enhanced by anomalous extratropical storm wave direction.

    Science.gov (United States)

    Harley, Mitchell D; Turner, Ian L; Kinsela, Michael A; Middleton, Jason H; Mumford, Peter J; Splinter, Kristen D; Phillips, Matthew S; Simmons, Joshua A; Hanslow, David J; Short, Andrew D

    2017-07-20

    Extratropical cyclones (ETCs) are the primary driver of large-scale episodic beach erosion along coastlines in temperate regions. However, key drivers of the magnitude and regional variability in rapid morphological changes caused by ETCs at the coast remain poorly understood. Here we analyze an unprecedented dataset of high-resolution regional-scale morphological response to an ETC that impacted southeast Australia, and evaluate the new observations within the context of an existing long-term coastal monitoring program. This ETC was characterized by moderate intensity (for this regional setting) deepwater wave heights, but an anomalous wave direction approximately 45 degrees more counter-clockwise than average. The magnitude of measured beach volume change was the largest in four decades at the long-term monitoring site and, at the regional scale, commensurate with that observed due to extreme North Atlantic hurricanes. Spatial variability in morphological response across the study region was predominantly controlled by alongshore gradients in storm wave energy flux and local coastline alignment relative to storm wave direction. We attribute the severity of coastal erosion observed due to this ETC primarily to its anomalous wave direction, and call for greater research on the impacts of changing storm wave directionality in addition to projected future changes in wave heights.

  11. Wave transmission by suspended pipe breakwater

    Digital Repository Service at National Institute of Oceanography (India)

    Mani, J.S.; Jayakumar, S.

    ratio of 0.46), a 5% reduction in incident-wave height can be achieved. The cost and performance of conventionally adopted pile breakwater (involving a row of closely spaced piles driven on the seabed) were compared with the present system...

  12. Projected wave conditions in the Eastern North Pacific under the influence of two CMIP5 climate scenarios

    Science.gov (United States)

    Erikson, Li H.; Hegermiller, Christie; Barnard, Patrick; Ruggiero, Peter; van Ormondt, Martin

    2015-01-01

    Hindcast and 21st century winds, simulated by General Circulation Models (GCMs), were used to drive global- and regional-scale spectral wind-wave generation models in the Pacific Ocean Basin to assess future wave conditions along the margins of the North American west coast and Hawaiian Islands. Three-hourly winds simulated by four separate GCMs were used to generate an ensemble of wave conditions for a recent historical time-period (1976–2005) and projections for the mid and latter parts of the 21st century under two radiative forcing scenarios (RCP 4.5 and RCP 8.5), as defined by the fifth phase of the Coupled Model Inter-comparison Project (CMIP5) experiments. Comparisons of results from historical simulations with wave buoy and ERA-Interim wave reanalysis data indicate acceptable model performance of wave heights, periods, and directions, giving credence to generating projections. Mean and extreme wave heights are projected to decrease along much of the North American west coast. Extreme wave heights are projected to decrease south of ∼50°N and increase to the north, whereas extreme wave periods are projected to mostly increase. Incident wave directions associated with extreme wave heights are projected to rotate clockwise at the eastern end of the Aleutian Islands and counterclockwise offshore of Southern California. Local spatial patterns of the changing wave climate are similar under the RCP 4.5 and RCP 8.5 scenarios, but stronger magnitudes of change are projected under RCP 8.5. Findings of this study are similar to previous work using CMIP3 GCMs that indicates decreasing mean and extreme wave conditions in the Eastern North Pacific, but differ from other studies with respect to magnitude and local patterns of change. This study contributes toward a larger ensemble of global and regional climate projections needed to better assess uncertainty of potential future wave climate change, and provides model boundary conditions for assessing the impacts of

  13. Wave persistence in central Bay of Bengal during the southwest monsoon

    Digital Repository Service at National Institute of Oceanography (India)

    Sathe, P.V.; Gouveia, A.D.

    to compute wave persistence is suggested and persistence diagrams for different wave height levels are presented for both rough and calm conditions and their implications discussed. Except in one case, values of H@ds@@ exceeded 1 m, and over 60% of values...

  14. Short-term statistics of waves measured off Ratnagiri, eastern Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Amrutha, M.M.; SanilKumar, V.

    coast of India have been analyzed to study the short-term statistics of waves covering full one year period. The study indicates that the values of the observed maximum wave height as a function of duration are not consistent with the theoretical...

  15. Amplification of tsunami heights by delayed rupture of great earthquakes along the Nankai trough

    Science.gov (United States)

    Imai, K.; Satake, K.; Furumura, T.

    2010-04-01

    We investigated the effect of delayed rupture of great earthquakes along the Nankai trough on tsunami heights on the Japanese coast. As the tsunami source, we used a model of the 1707 Hoei earthquake, which consists of four segments: Tokai, Tonankai, and two Nankai segments. We first searched for the worst case, in terms of coastal tsunami heights, of rupture delay time on each segment, on the basis of superposition principle for the linear long wave theory. When the rupture starts on the Tonankai segment, followed by rupture on the Tokai segment 21 min later, as well as the eastern and western Nankai segments 15 and 28 min later, respectively, the average coastal tsunami height becomes the largest. To quantify the tsunami amplification, we compared the coastal tsunami heights from the delayed rupture with those from the simultaneous rupture model. Along the coasts of the sea of Hyu'uga and in the Bungo Channel, the tsunami heights become significantly amplified (>1.4 times larger) relative to the simultaneous rupture. Along the coasts of Tosa Bay and in the Kii Channel, the tsunami heights become amplified about 1.2 times. Along the coasts of the sea of Kumano and Ise Bay, and the western Enshu coast, the tsunami heights become slightly smaller for the delayed rupture. Along the eastern Enshu coast, the coast of Suruga Bay, and the west coast of Sagami Bay, the tsunami heights become amplified about 1.1 times.

  16. Elevated levels of Hs-CRP and IL-6 after delivery are associated with depression during the 6 months post partum.

    Science.gov (United States)

    Liu, Hao; Zhang, Yang; Gao, Yutao; Zhang, Zhenyu

    2016-09-30

    The objective of this study is to determine whether inflammatory markers (high-sensitivity C-reactive protein (Hs-CRP) and interleukin (IL)-6) early in the postpartum period contribute to the development of postpartum depression (PPD). From 4 May 2014 to 30 June 2014, all eligible women not on medication for depression giving birth at the Beijing Chao-Yang hospital were consecutively recruited and followed up for 6 months. Depression symptoms were measured with the Edinburgh Postnatal Depression Scale (EPDS), and inflammatory biomarkers (Hs-CRP and IL-6) were tested. During the study period, 296 women were enrolled and completed follow-up. In these women, 45 (15.2%) were considered as meeting the criteria for PPD. Serum levels of Hs-CRP and IL-6 in women with PPD were significantly higher than those without PPD (all P<0.0001). Receiver operating characteristics to predict PPD demonstrated areas under the curve of IL-6 of 0.861 (95% confidence interval (CI), 0.801-0.922), which was superior to Hs-CRP (0.837 (95% CI, 0.781-0.894), P<0.01). In multivariate logistic regression analysis, IL-6 and Hs-CRP were independent predictors of PPD. The present study demonstrates a strong relationship between elevated serum Hs-CRP and IL-6 levels at admission and the development of PPD within 6 months. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  17. Exploring Dust Impacts on Tropical Systems from the NASA HS-3 Field Campaign

    Science.gov (United States)

    Nowottnick, Ed; Colarco, Pete; da Silva, Arlindo; Barahona, Donifan; Hlavka, Dennis

    2015-01-01

    One of the overall scientific goals of the NASA Hurricane and Severe Storm Sentinel (HS-3) field campaign is to better understand the role of the Saharan Air Layer (SAL) in tropical storm development. During the 2012 HS-3 deployment, the Cloud Physics Lidar (CPL) observed dust within SAL air in close proximity to a developing Nadine (September 11, 2012). Throughout the mission, the NASA GEOS-5 modeling system supported HS-3 by providing 0.25 degrees resolution 5-day global forecasts of aerosols, which were used to support mission planning. The aerosol module was radiatively interactive within the GEOS-5 model, but aerosols were not directly coupled to cloud and precipitation processes. In this study we revisit the aerosol forecasts with an updated version of the GEOS-5 model. For the duration of Hurricane Nadine, we run multiday climate simulations leading up to each respective Global Hawk flight with and without aerosol direct interaction. For each set of simulations, we compare simulated dust mass fluxes to identify differences in SAL entrainment related to the interaction between dust aerosols and the atmosphere. We find that the direct effects of dust induce a low level anticyclonic circulation that temporarily shields Nadine from the intrusion of dry air, leading to a more intense storm.

  18. Coral reef structural complexity provides important coastal protection from waves under rising sea levels

    Science.gov (United States)

    Harris, Daniel L.; Rovere, Alessio; Casella, Elisa; Power, Hannah; Canavesio, Remy; Collin, Antoine; Pomeroy, Andrew; Webster, Jody M.; Parravicini, Valeriano

    2018-01-01

    Coral reefs are diverse ecosystems that support millions of people worldwide by providing coastal protection from waves. Climate change and human impacts are leading to degraded coral reefs and to rising sea levels, posing concerns for the protection of tropical coastal regions in the near future. We use a wave dissipation model calibrated with empirical wave data to calculate the future increase of back-reef wave height. We show that, in the near future, the structural complexity of coral reefs is more important than sea-level rise in determining the coastal protection provided by coral reefs from average waves. We also show that a significant increase in average wave heights could occur at present sea level if there is sustained degradation of benthic structural complexity. Our results highlight that maintaining the structural complexity of coral reefs is key to ensure coastal protection on tropical coastlines in the future. PMID:29503866

  19. Osteoprotegerin improves risk detection by traditional cardiovascular risk factors and hsCRP

    DEFF Research Database (Denmark)

    Mogelvang, Rasmus; Haahr-Pedersen, Sune Ammentorp; Bjerre, Mette

    2013-01-01

    To evaluate the association of plasma osteoprotegerin (OPG) to hospitalisation for ischaemic heart disease (IHD), ischaemic stroke and all-cause mortality, and the effect of combining plasma OPG and high-sensitivity C-reactive protein (hsCRP)....

  20. Wave Transformation Over Reefs: Evaluation of One-Dimensional Numerical Models

    Science.gov (United States)

    2009-01-01

    level estimates. DISCLAIMER: The contents of this report are not to be used for advertising , publication, or promotional purposes. Citation of trade...better with data for wave heights and mean water levels obtained with the DDD85 formula for these mono- chromatic waves. The RMSE values (rms errors

  1. Clinical significance of determination of serum hypersensitive C-reactive protein (hs-CRP) and E-selectin levels in patients with coronary heart diseases

    International Nuclear Information System (INIS)

    Yang Chunxiu

    2007-01-01

    Objective: To investigate the significance of determination of serum contents of hs-CRP and E-Selectin in patients with coronary heart diseases (CHD). Methods: Serum hs-CRP Contents were determined with immuno-turbidity and E-Selectin contents were determined with ELISA in 58 patients with CHD (35SAP, 20UAP, 13AMI) and 35 controls. Results: Serum levels of hs-CRP and E-Selectin in CHD patients were significantly higher than those in controls (P 0.05). Conclusion: The serum levels of hs-CRP and E-Selectin were correlated to the development of CHD, but not to the coronary artery calibers. (authors)

  2. The Value of PCT, WBC and hs-CRP Tests in the Diagnosis and Prognosis of Children with Pneumonia%小儿肺炎中PCT、WBC、hs-CRP检测对疾病诊断及预后判断价值分析

    Institute of Scientific and Technical Information of China (English)

    夏兰兰; 李敬

    2017-01-01

    目的 分析小儿肺炎中PCT、WBC、hs-CRP检测对疾病诊断及预后的判断价值.方法 选取2015年5月至2016年4月在本院住院治疗的肺炎患儿120例作为观察组,健康儿童65例作为对照组.检测治疗前后患儿及健康儿童血清PCT、WBC、hs-CRP的变化.结果 治疗前,细菌感染组WBC数量(15.5±3.4)×109/L、hs-CRP水平(19.8±2.6) mg/L和PCT水平(21.9±2.1)ng/mL均明显高于非细菌感染组(6.8 ±2.3)×109/L、(4.5±2.3)mg/L、(4.7±1.8) ng/mL和健康对照组(8.1 ±1.4)×109/L、(3.5±1.2) mg/L、(1.8±0.5) ng/mL,且差异具有统计学意义(P<0.05).而非细菌感染组和健康对照组的WBC、hs-CRP和PCT结果差异无统计学意义(P>0.05);治疗后,细菌感染组WBC数量(7.3±1.4)×109/L、hs-CRP水平(5.1 ± 1.2) mg/L和PCT水平(2.3 ± 1.2) ng/mL均明显低于治疗前,差异具有统计学意义(P<0.05);WBC、hs-CRP、PCT联合检测的灵敏性95.2%、特异性93.0%、准确度93.3%显著高于WBC、hs-CRP、PCT单独检测,差异具有统计学意义(P<0.05).结论 在小儿肺炎治疗过程中,动态监测患儿血清的WBC、hs-CRP、PCT的变化,并结合临床,有助于诊疗和判断患儿疾病愈后的情况,具有显著的临床意义,值得推广应用.%Objective To estimate the value of PCT,WBC and hs-CRP tests in the diagnosis and prognosis of children with pneumonia.Methods 120 cases with pneumonia in children were selected from May 2015 to April 2016 in our hospital as the observation group,65 cases of healthy children as the control group.Changes of serum PCT,WBC and hs-CRP tests in children and healthy children before and after treatment were mearued.Results Before treatment,bacterial infection group have WBC count (15.5 ± 3.4) × 109/L,hs-CRP levels (19.8±2.6) mg/L and PCT level (21.9 ±2.1) ng/mL,which were significantly higher than those in non bacterial infection group (6.8 ±2.3) × 109/L,(4.5 ±2.3) mg/L,(4.7 ± 1.8) ng/mL and healthy control group (+ 8.1

  3. High-sensitivity c-reactive protein (hs-CRP) value with 90 days mortality in patients with heart failure

    Science.gov (United States)

    Nursyamsiah; Hasan, R.

    2018-03-01

    Hospitalization in patients with chronic heart failure is associated with high rates of mortality and morbidity that during treatment and post-treatment. Despite the various therapies available today, mortality and re-hospitalization rates within 60 to 90 days post-hospitalization are still quite high. This period is known as the vulnerable phase. With the prognostic evaluation tools in patients with heart failure are expected to help identify high-risk individuals, then more rigorous monitoring and interventions can be undertaken. To determine whether hs-CRP have an impact on mortality within 90 days in hospitalized patients with heart failure, an observational cohort study was conducted in 39 patients with heart failure who were hospitalized due to worsening chronic heart failure. Patients were followed for up to 90 days after initial evaluation with the primary endpoint is death. Hs-CRP value >4.25 mg/L we found 70% was dead and hs-CRP value <4.25 mg/L only 6.9% was dead whereas the survival within 90 days. p:0.000.In conclusion, there were differences in hs-CRP values between in patients with heart failure who died and survival within 90 days.

  4. Rogue waves in shallow water

    Science.gov (United States)

    Soomere, T.

    2010-07-01

    Most of the processes resulting in the formation of unexpectedly high surface waves in deep water (such as dispersive and geometrical focusing, interactions with currents and internal waves, reflection from caustic areas, etc.) are active also in shallow areas. Only the mechanism of modulational instability is not active in finite depth conditions. Instead, wave amplification along certain coastal profiles and the drastic dependence of the run-up height on the incident wave shape may substantially contribute to the formation of rogue waves in the nearshore. A unique source of long-living rogue waves (that has no analogues in the deep ocean) is the nonlinear interaction of obliquely propagating solitary shallow-water waves and an equivalent mechanism of Mach reflection of waves from the coast. The characteristic features of these processes are (i) extreme amplification of the steepness of the wave fronts, (ii) change in the orientation of the largest wave crests compared with that of the counterparts and (iii) rapid displacement of the location of the extreme wave humps along the crests of the interacting waves. The presence of coasts raises a number of related questions such as the possibility of conversion of rogue waves into sneaker waves with extremely high run-up. Also, the reaction of bottom sediments and the entire coastal zone to the rogue waves may be drastic.

  5. A multimodal wave spectrum-based approach for statistical downscaling of local wave climate

    Science.gov (United States)

    Hegermiller, Christie; Antolinez, Jose A A; Rueda, Ana C.; Camus, Paula; Perez, Jorge; Erikson, Li; Barnard, Patrick; Mendez, Fernando J.

    2017-01-01

    Characterization of wave climate by bulk wave parameters is insufficient for many coastal studies, including those focused on assessing coastal hazards and long-term wave climate influences on coastal evolution. This issue is particularly relevant for studies using statistical downscaling of atmospheric fields to local wave conditions, which are often multimodal in large ocean basins (e.g. the Pacific). Swell may be generated in vastly different wave generation regions, yielding complex wave spectra that are inadequately represented by a single set of bulk wave parameters. Furthermore, the relationship between atmospheric systems and local wave conditions is complicated by variations in arrival time of wave groups from different parts of the basin. Here, we address these two challenges by improving upon the spatiotemporal definition of the atmospheric predictor used in statistical downscaling of local wave climate. The improved methodology separates the local wave spectrum into “wave families,” defined by spectral peaks and discrete generation regions, and relates atmospheric conditions in distant regions of the ocean basin to local wave conditions by incorporating travel times computed from effective energy flux across the ocean basin. When applied to locations with multimodal wave spectra, including Southern California and Trujillo, Peru, the new methodology improves the ability of the statistical model to project significant wave height, peak period, and direction for each wave family, retaining more information from the full wave spectrum. This work is the base of statistical downscaling by weather types, which has recently been applied to coastal flooding and morphodynamic applications.

  6. Ultrasonic creeping wave test technique for dissimilar metal weld

    International Nuclear Information System (INIS)

    Yuan Jianzhong; Shang Junmin; Yan Zhi; Yuan Guanghua; Zhang Guofeng

    2009-01-01

    To solve the problem encountered in the defect inspection of the surface and near-surface of dissimilar metal weld effectively, a new ultrasonic creeping wave test technique is developed. In this paper, the test technique and its experimental verification are mainly described. The verification results show that linear defect, which is similar to the defect found in liquid penetrant test, on the surface and near-surface of dissimilar metal weld can be detected effectively, by using ultrasonic creeping wave test technique. And the depth, length and height of the defect can be determined easily. The effective covering depth of ultrasonic creeping wave test technique will reach 0-9 mm. Meanwhile, the planar defect, with equivalent area more than 3 mm 2 , existed in welds can be detected efficiently. So, accurate measurement, which self height dimension of planar defect is above 2 mm, will be realized. (authors)

  7. Moreton wave, "EIT wave", and type II radio burst as manifestations of a single wave front

    Science.gov (United States)

    Kuzmenko, I. V.; Grechnev, V. V.; Uralov, A. M.

    2011-12-01

    We show that a Moreton wave, an "EIT wave," and a type II radio burst observed during a solar flare of July 13, 2004, might have been a manifestation of a single front of a decelerating shock wave, which appeared in an active region (AR) during a filament eruption. We propose describing a quasi-spheroidal wave propagating upward and along the solar surface by using relations known from a theory of a point-like explosion in a gas whose density changes along the radius according to a power law. By applying this law to fit the drop in density of the coronal plasma enveloping the solar active region, we first managed to bring the measured positions and velocities of surface Moreton wave and "EIT wave" into correspondence with the observed frequency drift rate of the meter type II radio burst. The exponent of the vertical coronal density falloff is selected by fitting the power law to the Newkirk and Saito empirical distributions in the height range of interest. Formal use of such a dependence in the horizontal direction with a different exponent appears to be reasonable up to distances of less than 200 Mm around the eruption center. It is possible to assume that the near-surface shock wave weakens when leaving this radius and finally the active region, entering the region of the quiet Sun where the coronal plasma density and the fast-mode speed are almost constant along the horizontal.

  8. Nonlinear interaction of an intense radio wave with ionospheric D/E layer plasma

    Science.gov (United States)

    Sodha, Mahendra Singh; Agarwal, Sujeet Kumar

    2018-05-01

    This paper considers the nonlinear interaction of an intense electromagnetic wave with the D/E layer plasma in the ionosphere. A simultaneous solution of the electromagnetic wave equation and the equations describing the kinetics of D/E layer plasma is obtained; the phenomenon of ohmic heating of electrons by the electric field of the wave causes enhanced collision frequency and ionization of neutral species. Electron temperature dependent recombination of electrons with ions, electron attachment to O 2 molecules, and detachment of electrons from O2 - ions has also been taken into account. The dependence of the plasma parameters on the square of the electric vector of the wave E0 2 has been evaluated for three ionospheric heights (viz., 90, 100, and 110 km) corresponding to the mid-latitude mid-day ionosphere and discussed; these results are used to investigate the horizontal propagation of an intense radio wave at these heights.

  9. Wave modelling for the North Indian Ocean using MSMR analysed winds

    Digital Repository Service at National Institute of Oceanography (India)

    Vethamony, P.; Sudheesh, K.; Rupali, S.P.; Babu, M.T.; Jayakumar, S.; Saran, A; Basu, S.K.; Kumar, R.; Sarkar, A

    prediction when NCMRWF winds blended with MSMR winds are utilised in the wave model. A comparison between buoy and TOPEX wave heights of May 2000 at 4 buoy locations provides a good match, showing the merit of using altimeter data, wherever it is difficult...

  10. Effects of Silybum marianum (L.) Gaertn. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial.

    Science.gov (United States)

    Ebrahimpour Koujan, Soraiya; Gargari, Bahram Pourghassem; Mobasseri, Majid; Valizadeh, Hadi; Asghari-Jafarabadi, Mohammad

    2015-02-15

    Diabetes is a serious metabolic disorder and oxidative stress and inflammation contribute to its pathogenesis and complications. Since Silybum marianum (L.) Gaertn. (silymarin) extract is an antioxidant with anti-inflammatory properties, this randomized clinical trial was conducted to evaluate the effects of silymarin supplementation on oxidative stress indices and hs-CRP in type 2 diabetes mellitus patients. For the present paralleled, randomized, triple-blinded, placebo-controlled clinical trial, 40 type 2 diabetes patients aged 25-50 yr old and on stable medication were recruited from the Iranian Diabetes Society and endocrinology clinics in East Azarbayjan (Tabriz, Iran) and randomly assigned into two groups. Patients in the silymarin treatment group received 140 mg, thrice daily of dried extracts of Silybum marianum (n = 20) and those in the placebo group (n = 20) received identical placebos for 45 days. Data pertaining to height, weight, waist circumference and BMI, as well as food consumption, were collected at base line and at the conclusion of the study. Fasting blood samples were obtained and antioxidant indices and hs-CRP were assessed at baseline, as well as at the end of the trial. All 40 patients completed the study and did not report any adverse effects or symptoms with the silymarin supplementation. Silymarin supplementation significantly increased superoxide dismutase (SOD), glutathione peroxidase (GPX) activity and total antioxidant capacity (TAC) compared to patients taking the placebo, by 12.85%, 30.32% and 8.43%, respectively (p concentration significantly decreased by 12.01% (p antioxidant indices (SOD, GPX and TAC) and decrease hs-CRP levels in T2DM patients. Copyright © 2015. Published by Elsevier GmbH.

  11. Future wave and wind projections for United States and United-States-affiliated Pacific Islands

    Science.gov (United States)

    Storlazzi, Curt D.; Shope, James B.; Erikson, Li H.; Hegermiller, Christine A.; Barnard, Patrick L.

    2015-01-01

    Changes in future wave climates in the tropical Pacific Ocean from global climate change are not well understood. Spatially and temporally varying waves dominate coastal morphology and ecosystem structure of the islands throughout the tropical Pacific. Waves also impact coastal infrastructure, natural and cultural resources, and coastal-related economic activities of the islands. Wave heights, periods, and directions were forecast through the year 2100 using wind parameter outputs from four atmosphere-ocean global climate models from the Coupled Model Inter-Comparison Project, Phase 5, for Representative Concentration Pathways (RCP) scenarios 4.5 and 8.5 that correspond to moderately mitigated and unmitigated greenhouse gas emissions, respectively. Wind fields from the global climate models were used to drive a global WAVEWATCH-III wave model and generate hourly time-series of bulk wave parameters for 25 islands in the mid to western tropical Pacific for the years 1976–2005 (historical), 2026–2045 (mid-century projection), and 2085–2100 (end-of-century projection). Although the results show some spatial heterogeneity, overall the December-February extreme significant wave heights, defined as the mean of the top 5 percent of significant wave height time-series data modeled within a specific period, increase from present to mid-century and then decrease toward the end of the century; June-August extreme wave heights increase throughout the century within the Central region of the study area; and September-November wave heights decrease strongly throughout the 21st century, displaying the largest and most widespread decreases of any season. Peak wave periods increase east of the International Date Line during the December-February and June-August seasons under RCP4.5. Under the RCP8.5 scenario, wave periods decrease west of the International Date Line during December-February but increase in the eastern half of the study area. Otherwise, wave periods decrease

  12. HS-173, a Novel PI3K Inhibitor, Attenuates the Activation of Hepatic Stellate Cells in Liver Fibrosis

    Science.gov (United States)

    Son, Mi Kwon; Ryu, Ye-Lim; Jung, Kyung Hee; Lee, Hyunseung; Lee, Hee Seung; Yan, Hong Hua; Park, Heon Joo; Ryu, Ji-Kan; Suh, Jun–Kyu; Hong, Sungwoo; Hong, Soon-Sun

    2013-01-01

    Hepatic stellate cells (HSCs) are the primary source of matrix components in liver disease such as fibrosis. Phosphatidylinositol 3-kinase (PI3K) signaling in HSCs has been shown to induce fibrogenesis. In this study, we evaluated the anti-fibrotic activity of a novel imidazopyridine analogue (HS-173) in human HSCs as well as mouse liver fibrosis. HS-173 strongly suppressed the growth and proliferation of HSCs and induced the arrest at the G2/M phase and apoptosis in HSCs. Furthermore, it reduced the expression of extracellular matrix components such as collagen type I, which was confirmed by an in vivo study. We also observed that HS-173 blocked the PI3K/Akt signaling pathway in vitro and in vivo. Taken together, HS-173 suppressed fibrotic responses such as cell proliferation and collagen synthesis by blocking PI3K/Akt signaling. Therefore, we suggest that this compound may be an effective therapeutic agent for ameliorating liver fibrosis through the inhibition of PI3K signaling. PMID:24326778

  13. Correlation of hs-CRP with environmental risk factors of nephropathy in type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Jay Prakash Sah

    2015-06-01

    Full Text Available The objective of the present study was to investigate the association of hs-CRP levels with environmental risk factors of diabetic nephropathy like smoking, drinking alcohol, diet, age of diabetic patient, duration of diabetes, medication of diabetes, and blood pressure medication. A hospital-based quantitative study was conducted at the Department of Clinical Biochemistry of Manipal Teaching Hospital (MTH Pokhara, Nepal, with 89 patients suffering from type 2 diabetes. Blood samples (n=89 from the patients were collected and the serums were separated. On the other hand, data on environmental risk factors of nephropathy were collected by using standard questionnaire. In this study, serum hs-CRP level was not found to be correlated with smoking (p=0.111, alcohol consumption (p=0.722, diet (p=0.496, duration of diabetes (p=0.519, age of diabetic patient (p=0.369, medication of diabetes (p=0.734, and blood pressure medication (p=0.625. Hence, our study concludes that serum hs-CRP value in type 2 diabetic patients is insignificantly correlated with the risk factors especially smoking, drinking alcohol, diet, duration of diabetes, age of diabetic patient, medication of diabetes, and medication of blood pressure.

  14. Agreement between measured height, and height predicted from ...

    African Journals Online (AJOL)

    lower limb measurements, such as knee height, as well as upper limb measures ... had with bone injuries/fractures affecting height or ulna length; and n = 1 had a ... and heels, buttocks and upper back in contact with the vertical surface of the .... found striking similarity in linear growth of infants to five-year- olds among all ...

  15. Lowering the quantification limit of the QubitTM RNA HS assay using RNA spike-in.

    Science.gov (United States)

    Li, Xin; Ben-Dov, Iddo Z; Mauro, Maurizio; Williams, Zev

    2015-05-06

    RNA quantification is often a prerequisite for most RNA analyses such as RNA sequencing. However, the relatively low sensitivity and large sample consumption of traditional RNA quantification methods such as UV spectrophotometry and even the much more sensitive fluorescence-based RNA quantification assays, such as the Qubit™ RNA HS Assay, are often inadequate for measuring minute levels of RNA isolated from limited cell and tissue samples and biofluids. Thus, there is a pressing need for a more sensitive method to reliably and robustly detect trace levels of RNA without interference from DNA. To improve the quantification limit of the Qubit™ RNA HS Assay, we spiked-in a known quantity of RNA to achieve the minimum reading required by the assay. Samples containing trace amounts of RNA were then added to the spike-in and measured as a reading increase over RNA spike-in baseline. We determined the accuracy and precision of reading increases between 1 and 20 pg/μL as well as RNA-specificity in this range, and compared to those of RiboGreen(®), another sensitive fluorescence-based RNA quantification assay. We then applied Qubit™ Assay with RNA spike-in to quantify plasma RNA samples. RNA spike-in improved the quantification limit of the Qubit™ RNA HS Assay 5-fold, from 25 pg/μL down to 5 pg/μL while maintaining high specificity to RNA. This enabled quantification of RNA with original concentration as low as 55.6 pg/μL compared to 250 pg/μL for the standard assay and decreased sample consumption from 5 to 1 ng. Plasma RNA samples that were not measurable by the Qubit™ RNA HS Assay were measurable by our modified method. The Qubit™ RNA HS Assay with RNA spike-in is able to quantify RNA with high specificity at 5-fold lower concentration and uses 5-fold less sample quantity than the standard Qubit™ Assay.

  16. Accuracy of recumbent height measurement.

    Science.gov (United States)

    Gray, D S; Crider, J B; Kelley, C; Dickinson, L C

    1985-01-01

    Since many patients requiring specialized nutritional support are bedridden, measurement of height for purposes of nutritional assessment or prescription must often be done with the patient in bed. This study examined the accuracy of measuring body height in bed in the supine position. Two measurements were performed on 108 ambulatory inpatients: (1) standing height using a standard height-weight scale, and (2) bed height using a flexible tape. Patients were divided into four groups based on which of two researchers performed each of the two measurements. Each patient was also weighed and self-reported height, weight, sex, and age were recorded. Bed height was significantly longer than standing height by 3.68 cm, but the two measurements were equally precise. It was believed, however, that this 2% difference was probably not clinically significant in most circumstances. Bed height correlated highly with standing height (r = 0.95), and the regression equation was standing height = 13.82 +/- 0.09 bed height. Patients overestimated their heights. Heights recorded by nurses were more accurate when patients were measured than when asked about their heights, but the patients were more often asked than measured.

  17. Spectroscopic Evidence of Alfvén Wave Damping in the Off-limb Solar Corona

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, G. R., E-mail: girjesh@iucaa.in [Inter-University Centre for Astronomy and Astrophysics, Post Bag-4, Ganeshkhind, Pune 411007 (India)

    2017-02-10

    We investigate the off-limb active-region and quiet-Sun corona using spectroscopic data. The active region is clearly visible in several spectral lines formed in the temperature range of 1.1–2.8 MK. We derive the electron number density using the line ratio method, and the nonthermal velocity in the off-limb region up to the distance of 140 Mm. We compare density scale heights derived from several spectral line pairs with expected scale heights per the hydrostatic equilibrium model. Using several isolated and unblended spectral line profiles, we estimate nonthermal velocities in the active region and quiet Sun. Nonthermal velocities obtained from warm lines in the active region first show an increase and then later either a decrease or remain almost constant with height in the far off-limb region, whereas nonthermal velocities obtained from hot lines show consistent decrease. However, in the quiet-Sun region, nonthermal velocities obtained from various spectral lines show either a gradual decrease or remain almost constant with height. Using these obtained parameters, we further calculate Alfvén wave energy flux in both active and quiet-Sun regions. We find a significant decrease in wave energy fluxes with height, and hence provide evidence of Alfvén wave damping. Furthermore, we derive damping lengths of Alfvén waves in the both regions and find them to be in the range of 25–170 Mm. Different damping lengths obtained at different temperatures may be explained as either possible temperature-dependent damping or by measurements obtained in different coronal structures formed at different temperatures along the line of sight. Temperature-dependent damping may suggest some role of thermal conduction in the damping of Alfvén waves in the lower corona.

  18. ANALYTICAL SOLUTION FOR WAVES IN PLANETS WITH ATMOSPHERIC SUPERROTATION. II. LAMB, SURFACE, AND CENTRIFUGAL WAVES

    International Nuclear Information System (INIS)

    Peralta, J.; López-Valverde, M. A.; Imamura, T.; Read, P. L.; Luz, D.; Piccialli, A.

    2014-01-01

    This paper is the second in a two-part study devoted to developing tools for a systematic classification of the wide variety of atmospheric waves expected on slowly rotating planets with atmospheric superrotation. Starting with the primitive equations for a cyclostrophic regime, we have deduced the analytical solution for the possible waves, simultaneously including the effect of the metric terms for the centrifugal force and the meridional shear of the background wind. In those cases where the conditions for the method of the multiple scales in height are met, these wave solutions are also valid when vertical shear of the background wind is present. A total of six types of waves have been found and their properties were characterized in terms of the corresponding dispersion relations and wave structures. In this second part, we study the waves' solutions when several atmospheric approximations are applied: Lamb, surface, and centrifugal waves. Lamb and surface waves are found to be quite similar to those in a geostrophic regime. By contrast, centrifugal waves turn out to be a special case of Rossby waves that arise in atmospheres in cyclostrophic balance. Finally, we use our results to identify the nature of the waves behind atmospheric periodicities found in polar and lower latitudes of Venus's atmosphere

  19. ANALYTICAL SOLUTION FOR WAVES IN PLANETS WITH ATMOSPHERIC SUPERROTATION. II. LAMB, SURFACE, AND CENTRIFUGAL WAVES

    Energy Technology Data Exchange (ETDEWEB)

    Peralta, J.; López-Valverde, M. A. [Instituto de Astrofísica de Andalucía (CSIC), Glorieta de la Astronomía, 18008 Granada (Spain); Imamura, T. [Institute of Space and Astronautical Science-Japan Aerospace Exploration Agency 3-1-1, Yoshinodai, Chuo-ku, Sagamihara, Kanagawa 252-5210 (Japan); Read, P. L. [Clarendon Laboratory, Department of Physics, University of Oxford, Parks Road, Oxford (United Kingdom); Luz, D. [Centro de Astronomia e Astrofísica da Universidade de Lisboa (CAAUL), Observatório Astronómico de Lisboa, Tapada da Ajuda, 1349-018 Lisboa (Portugal); Piccialli, A., E-mail: peralta@iaa.es [LATMOS, UVSQ, 11 bd dAlembert, 78280 Guyancourt (France)

    2014-07-01

    This paper is the second in a two-part study devoted to developing tools for a systematic classification of the wide variety of atmospheric waves expected on slowly rotating planets with atmospheric superrotation. Starting with the primitive equations for a cyclostrophic regime, we have deduced the analytical solution for the possible waves, simultaneously including the effect of the metric terms for the centrifugal force and the meridional shear of the background wind. In those cases where the conditions for the method of the multiple scales in height are met, these wave solutions are also valid when vertical shear of the background wind is present. A total of six types of waves have been found and their properties were characterized in terms of the corresponding dispersion relations and wave structures. In this second part, we study the waves' solutions when several atmospheric approximations are applied: Lamb, surface, and centrifugal waves. Lamb and surface waves are found to be quite similar to those in a geostrophic regime. By contrast, centrifugal waves turn out to be a special case of Rossby waves that arise in atmospheres in cyclostrophic balance. Finally, we use our results to identify the nature of the waves behind atmospheric periodicities found in polar and lower latitudes of Venus's atmosphere.

  20. A unified spectral parameterization for wave breaking: From the deep ocean to the surf zone

    Science.gov (United States)

    Filipot, J.-F.; Ardhuin, F.

    2012-11-01

    A new wave-breaking dissipation parameterization designed for phase-averaged spectral wave models is presented. It combines wave breaking basic physical quantities, namely, the breaking probability and the dissipation rate per unit area. The energy lost by waves is first explicitly calculated in physical space before being distributed over the relevant spectral components. The transition from deep to shallow water is made possible by using a dissipation rate per unit area of breaking waves that varies with the wave height, wavelength and water depth. This parameterization is implemented in the WAVEWATCH III modeling framework, which is applied to a wide range of conditions and scales, from the global ocean to the beach scale. Wave height, peak and mean periods, and spectral data are validated using in situ and remote sensing data. Model errors are comparable to those of other specialized deep or shallow water parameterizations. This work shows that it is possible to have a seamless parameterization from the deep ocean to the surf zone.

  1. The wind sea and swell waves climate in the Nordic seas

    Science.gov (United States)

    Semedo, Alvaro; Vettor, Roberto; Breivik, Øyvind; Sterl, Andreas; Reistad, Magnar; Soares, Carlos Guedes; Lima, Daniela

    2015-02-01

    A detailed climatology of wind sea and swell waves in the Nordic Seas (North Sea, Norwegian Sea, and Barents Sea), based on the high-resolution reanalysis NORA10, developed by the Norwegian Meteorological Institute, is presented. The higher resolution of the wind forcing fields, and the wave model (10 km in both cases), along with the inclusion of the bottom effect, allowed a better description of the wind sea and swell features, compared to previous global studies. The spatial patterns of the swell-dominated regional wave fields are shown to be different from the open ocean, due to coastal geometry, fetch dimensions, and island sheltering. Nevertheless, swell waves are still more prevalent and carry more energy in the Nordic Seas, with the exception of the North Sea. The influence of the North Atlantic Oscillation on the winter regional wind sea and swell patterns is also presented. The analysis of the decadal trends of wind sea and swell heights during the NORA10 period (1958-2001) shows that the long-term trends of the total significant wave height (SWH) in the Nordic Seas are mostly due to swell and to the wave propagation effect.

  2. HURRICANE AND SEVERE STORM SENTINEL (HS3) HURRICANE IMAGING RADIOMETER (HIRAD) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The Hurricane and Severe Storm Sentinel (HS3) Hurricane Imaging Radiometer (HIRAD) was collected by the Hurricane Imaging Radiometer (HIRAD), which was a multi-band...

  3. Tissue-Specific Methylation of Long Interspersed Nucleotide Element-1 of Homo Sapiens (L1Hs) During Human Embryogenesis and Roles in Neural Tube Defects.

    Science.gov (United States)

    Wang, L; Chang, S; Guan, J; Shangguan, S; Lu, X; Wang, Z; Wu, L; Zou, J; Zhao, H; Bao, Y; Qiu, Z; Niu, B; Zhang, T

    2015-01-01

    Epigenetic regulation of long interspersed nucleotide element-1 (LINE-1) retrotransposition events plays crucial roles during early development. Previously we showed that LINE-1 hypomethylation in neuronal tissues is associated with pathogenesis of neural tube defect (NTD). Herein, we further evaluated LINE-1 Homo sapiens (L1Hs) methylation in tissues derived from three germ layers of stillborn NTD fetuses, to define patterns of tissue specific methylation and site-specific hypomethylation at CpG sites within an L1Hs promoter region. Stable, tissue-specific L1Hs methylation patterns throughout three germ layer lineages of the fetus, placenta, and maternal peripheral blood were observed. Samples from maternal peripheral blood exhibited the highest level of L1Hs methylation (64.95%) and that from placenta showed the lowest (26.82%). Between samples from NTDs and controls, decrease in L1Hs methylation was only significant in NTD-affected brain tissue at 7.35%, especially in females (8.98%). L1Hs hypomethylation in NTDs was also associated with a significant increase in expression level of an L1Hs-encoded transcript in females (r = -0.846, p = 0.004). This could be due to genomic DNA instability and alternation in chromatins accessibility resulted from abnormal L1Hs hypomethylation, as showed in this study with HCT-15 cells treated with methylation inhibitor 5-Aza.

  4. A Machine LearningFramework to Forecast Wave Conditions

    Science.gov (United States)

    Zhang, Y.; James, S. C.; O'Donncha, F.

    2017-12-01

    Recently, significant effort has been undertaken to quantify and extract wave energy because it is renewable, environmental friendly, abundant, and often close to population centers. However, a major challenge is the ability to accurately and quickly predict energy production, especially across a 48-hour cycle. Accurate forecasting of wave conditions is a challenging undertaking that typically involves solving the spectral action-balance equation on a discretized grid with high spatial resolution. The nature of the computations typically demands high-performance computing infrastructure. Using a case-study site at Monterey Bay, California, a machine learning framework was trained to replicate numerically simulated wave conditions at a fraction of the typical computational cost. Specifically, the physics-based Simulating WAves Nearshore (SWAN) model, driven by measured wave conditions, nowcast ocean currents, and wind data, was used to generate training data for machine learning algorithms. The model was run between April 1st, 2013 and May 31st, 2017 generating forecasts at three-hour intervals yielding 11,078 distinct model outputs. SWAN-generated fields of 3,104 wave heights and a characteristic period could be replicated through simple matrix multiplications using the mapping matrices from machine learning algorithms. In fact, wave-height RMSEs from the machine learning algorithms (9 cm) were less than those for the SWAN model-verification exercise where those simulations were compared to buoy wave data within the model domain (>40 cm). The validated machine learning approach, which acts as an accurate surrogate for the SWAN model, can now be used to perform real-time forecasts of wave conditions for the next 48 hours using available forecasted boundary wave conditions, ocean currents, and winds. This solution has obvious applications to wave-energy generation as accurate wave conditions can be forecasted with over a three-order-of-magnitude reduction in

  5. Sinking/floatation of pipelines and other objects in liquefied soil under waves

    DEFF Research Database (Denmark)

    Sumer, B. Mutlu; Fredsøe, Jørgen; Christensen, S.

    1999-01-01

    , and the experiments with the structure model (a pipeline, a sphere, and a cube). In the former experiments, the pore-water pressure was measured across the soil depth. The pore-water pressure built up, as the waves progressed. The soil was liquefied for wave heights larger than a critical value. Regarding......This paper presents the results of an experimental study where the sinking and floatation of a pipeline and other objects (namely, a sphere and a cube) in a silt bed was investigated. The bed was exposed to progressive waves. Two kinds of experiments were made: The undisturbed-flow experiments...... the experiments with the structure model, the displacement of the structure (sinking or floatation) was measured simultaneously with the pore-water pressure. The influence of various parameters (such as the initial position of the object, the specific gravity, the soil layer thickness, and the wave height...

  6. Long-term MST radar observations of vertical wave number spectra of gravity waves in the tropical troposphere over Gadanki (13.5° N, 79.2° E: comparison with model spectra

    Directory of Open Access Journals (Sweden)

    S. Vijaya Bhaskara Rao

    2008-06-01

    Full Text Available The potential utility of Mesosphere-Stratosphere-Troposphere (MST radar measurements of zonal, meridional and vertical winds for divulging the gravity wave vertical wave number spectra is discussed. The data collected during the years 1995–2004 are used to obtain the mean vertical wave number spectra of gravity wave kinetic energy in the tropical troposphere over Gadanki (13.5° N, 79.2° E. First, the climatology of 3-dimensional wind components is developed using ten years of radar observations, for the first time, over this latitude. This climatology brought out the salient features of background tropospheric winds over Gadanki. Further, using the second order polynomial fit as background, the day-to-day wind anomalies are estimated. These wind anomalies in the 4–14 km height regions are used to estimate the profiles of zonal, meridional and vertical kinetic energy per unit mass, which are then used to estimate the height profile of total kinetic energy. Finally, the height profiles of total kinetic energy are subjected to Fourier analysis to obtain the monthly mean vertical wave number spectra of gravity wave kinetic energy. The monthly mean vertical wave number spectra are then compared with a saturation spectrum predicted by gravity wave saturation theory. A slope of 5/3 is used for the model gravity wave spectrum estimation. In general, the agreement is good during all the months. However, it is noticed that the model spectrum overestimates the PSD at lower vertical wave numbers and underestimates it at higher vertical wave numbers, which is consistently observed during all the months. The observed discrepancies are attributed to the differences in the slopes of theoretical and observed gravity wave spectra. The slopes of the observed vertical wave number spectra are estimated and compared with the model spectrum slope, which are in good agreement. The estimated slopes of the observed monthly vertical wave number spectra are in the

  7. Association of HS6ST3 gene polymorphisms with obesity and ...

    Indian Academy of Sciences (India)

    Supplementary data: Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene × gender interaction. Ke-Sheng Wang, Liang Wang, Xuefeng Liu and Min Zeng. J. Genet. 92, 395–402. Table 1. Associations of 117 SNPs with obesity in the Health ABC and Marshfield samples. Minor. OR Health.

  8. Final height in survivors of childhood cancer compared with Height Standard Deviation Scores at diagnosis.

    Science.gov (United States)

    Knijnenburg, S L; Raemaekers, S; van den Berg, H; van Dijk, I W E M; Lieverst, J A; van der Pal, H J; Jaspers, M W M; Caron, H N; Kremer, L C; van Santen, H M

    2013-04-01

    Our study aimed to evaluate final height in a cohort of Dutch childhood cancer survivors (CCS) and assess possible determinants of final height, including height at diagnosis. We calculated standard deviation scores (SDS) for height at initial cancer diagnosis and height in adulthood in a cohort of 573 CCS. Multivariable regression analyses were carried out to estimate the influence of different determinants on height SDS at follow-up. Overall, survivors had a normal height SDS at cancer diagnosis. However, at follow-up in adulthood, 8.9% had a height ≤-2 SDS. Height SDS at diagnosis was an important determinant for adult height SDS. Children treated with (higher doses of) radiotherapy showed significantly reduced final height SDS. Survivors treated with total body irradiation (TBI) and craniospinal radiation had the greatest loss in height (-1.56 and -1.37 SDS, respectively). Younger age at diagnosis contributed negatively to final height. Height at diagnosis was an important determinant for height SDS at follow-up. Survivors treated with TBI, cranial and craniospinal irradiation should be monitored periodically for adequate linear growth, to enable treatment on time if necessary. For correct interpretation of treatment-related late effects studies in CCS, pre-treatment data should always be included.

  9. Development of a Direct Headspace Collection Method from Arabidopsis Seedlings Using HS-SPME-GC-TOF-MS Analysis

    Directory of Open Access Journals (Sweden)

    Kazuki Saito

    2013-04-01

    Full Text Available Plants produce various volatile organic compounds (VOCs, which are thought to be a crucial factor in their interactions with harmful insects, plants and animals. Composition of VOCs may differ when plants are grown under different nutrient conditions, i.e., macronutrient-deficient conditions. However, in plants, relationships between macronutrient assimilation and VOC composition remain unclear. In order to identify the kinds of VOCs that can be emitted when plants are grown under various environmental conditions, we established a conventional method for VOC profiling in Arabidopsis thaliana (Arabidopsis involving headspace-solid-phase microextraction-gas chromatography-time-of-flight-mass spectrometry (HS-SPME-GC-TOF-MS. We grew Arabidopsis seedlings in an HS vial to directly perform HS analysis. To maximize the analytical performance of VOCs, we optimized the extraction method and the analytical conditions of HP-SPME-GC-TOF-MS. Using the optimized method, we conducted VOC profiling of Arabidopsis seedlings, which were grown under two different nutrition conditions, nutrition-rich and nutrition-deficient conditions. The VOC profiles clearly showed a distinct pattern with respect to each condition. This study suggests that HS-SPME-GC-TOF-MS analysis has immense potential to detect changes in the levels of VOCs in not only Arabidopsis, but other plants grown under various environmental conditions.

  10. Association of serum hs-CRP and lipids with obesity in school children in a 12-month follow-up study in Japan.

    Science.gov (United States)

    Nishide, Ritsuko; Ando, Michiko; Funabashi, Hidemitsu; Yoda, Yoshiko; Nakano, Masataka; Shima, Masayuki

    2015-03-01

    To investigate the association of serum lipids and high-sensitivity C-reactive protein (hs-CRP) with obesity in school children and to explore whether hs-CRP levels could be used to predict the presence or absence of obesity 12 months later. The subjects were school children (6-11 years old) in Japan. Blood sampling and physical measurements were performed in school (2001); low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides, and hs-CRP levels were measured. Data from children who could be followed 12 months later were analyzed. Subjects weighing 20% or more over his/her standard weight were regarded as obese, and the association of obesity with serum parameters was analyzed. Data from 612 subjects were analyzed (follow-up rate, 75.4%). The mean of each serum parameter was significantly higher (inverse for HDL-C; lower) in obese than that in non-obese children. Logistic regression analysis for obesity at baseline showed that the odds ratio (OR) of hs-CRP was the highest [OR, 2.15; 95% confidence interval (CI), 1.65-2.78 for an interquartile rage (IQR) increase]; the association with triglycerides and LDL-C/HDL-C was significant. At the 12-month follow-up, the OR of high hs-CRP remained the highest of all serum parameters (2.09; 95% CI, 1.63-2.69 for an IQR increase). High levels of triglycerides, LDL-C/HDL-C, and hs-CRP increased the risk of obesity in school children. Hs-CRP is considered to be a better predictor of obesity 12 months later than is LDL-C/HDL-C.

  11. Experimental and numerical investigations of temporally and spatially periodic modulated wave trains

    Science.gov (United States)

    Houtani, H.; Waseda, T.; Tanizawa, K.

    2018-03-01

    A number of studies on steep nonlinear waves were conducted experimentally with the temporally periodic and spatially evolving (TPSE) wave trains and numerically with the spatially periodic and temporally evolving (SPTE) ones. The present study revealed that, in the vicinity of their maximum crest height, the wave profiles of TPSE and SPTE modulated wave trains resemble each other. From the investigation of the Akhmediev-breather solution of the nonlinear Schrödinger equation (NLSE), it is revealed that the dispersion relation deviated from the quadratic dependence of frequency on wavenumber and became linearly dependent instead. Accordingly, the wave profiles of TPSE and SPTE breathers agree. The range of this agreement is within the order of one wave group of the maximum crest height and persists during the long-term evolution. The findings extend well beyond the NLSE regime and can be applied to modulated wave trains that are highly nonlinear and broad-banded. This was demonstrated from the numerical wave tank simulations with a fully nonlinear potential flow solver based on the boundary element method, in combination with the nonlinear wave generation method based on the prior simulation with the higher-order spectral model. The numerical wave tank results were confirmed experimentally in a physical wave tank. The findings of this study unravel the fundamental nature of the nonlinear wave evolution. The deviation of the dispersion relation of the modulated wave trains occurs because of the nonlinear phase variation due to quasi-resonant interaction, and consequently, the wave geometry of temporally and spatially periodic modulated wave trains coincides.

  12. Kinematics and dynamics of green water on a fixed platform in a large wave basin in focusing wave and random wave conditions

    Science.gov (United States)

    Chuang, Wei-Liang; Chang, Kuang-An; Mercier, Richard

    2018-06-01

    Green water kinematics and dynamics due to wave impingements on a simplified geometry, fixed platform were experimentally investigated in a large, deep-water wave basin. Both plane focusing waves and random waves were employed in the generation of green water. The focusing wave condition was designed to create two consecutive plunging breaking waves with one impinging on the frontal vertical wall of the fixed platform, referred as wall impingement, and the other directly impinging on the deck surface, referred as deck impingement. The random wave condition was generated using the JONSWAP spectrum with a significant wave height approximately equal to the freeboard. A total of 179 green water events were collected in the random wave condition. By examining the green water events in random waves, three different flow types are categorized: collapse of overtopping wave, fall of bulk water, and breaking wave crest. The aerated flow velocity was measured using bubble image velocimetry, while the void fraction was measured using fiber optic reflectometry. For the plane focusing wave condition, measurements of impact pressure were synchronized with the flow velocity and void fraction measurements. The relationship between the peak pressures and the pressure rise times is examined. For the high-intensity impact in the deck impingement events, the peak pressures are observed to be proportional to the aeration levels. The maximum horizontal velocities in the green water events in random waves are well represented by the lognormal distribution. Ritter's solution is shown to quantitatively describe the green water velocity distributions under both the focusing wave condition and the random wave condition. A prediction equation for green water velocity distribution under random waves is proposed.

  13. A statistical methodology for the estimation of extreme wave conditions for offshore renewable applications

    DEFF Research Database (Denmark)

    Larsén, Xiaoli Guo; Kalogeri, Christina; Galanis, George

    2015-01-01

    and post-process outputs from a high resolution numerical wave modeling system for extreme wave estimation based on the significant wave height. This approach is demonstrated through the data analysis at a relatively deep water site, FINO 1, as well as a relatively shallow water area, coastal site Horns...... as a characteristic index of extreme wave conditions. The results from the proposed methodology seem to be in a good agreement with the measurements at both the relatively deep, open water and the shallow, coastal water sites, providing a potentially useful tool for offshore renewable energy applications. © 2015...... Rev, which is located in the North Sea, west of Denmark. The post-processing targets at correcting the modeled time series of the significant wave height, in order to match the statistics of the corresponding measurements, including not only the conventional parameters such as the mean and standard...

  14. Wave model downscaling for coastal applications

    Science.gov (United States)

    Valchev, Nikolay; Davidan, Georgi; Trifonova, Ekaterina; Andreeva, Nataliya

    2010-05-01

    Downscaling is a suitable technique for obtaining high-resolution estimates from relatively coarse-resolution global models. Dynamical and statistical downscaling has been applied to the multidecadal simulations of ocean waves. Even as large-scale variability might be plausibly estimated from these simulations, their value for the small scale applications such as design of coastal protection structures and coastal risk assessment is limited due to their relatively coarse spatial and temporal resolutions. Another advantage of the high resolution wave modeling is that it accounts for shallow water effects. Therefore, it can be used for both wave forecasting at specific coastal locations and engineering applications that require knowledge about extreme wave statistics at or near the coastal facilities. In the present study downscaling is applied to both ECMWF and NCEP/NCAR global reanalysis of atmospheric pressure over the Black Sea with 2.5 degrees spatial resolution. A simplified regional atmospheric model is employed for calculation of the surface wind field at 0.5 degrees resolution that serves as forcing for the wave models. Further, a high-resolution nested WAM/SWAN wave model suite of nested wave models is applied for spatial downscaling. It aims at resolving the wave conditions in a limited area at the close proximity to the shore. The pilot site is located in the northern part the Bulgarian Black Sea shore. The system involves the WAM wave model adapted for basin scale simulation at 0.5 degrees spatial resolution. The WAM output for significant wave height, mean wave period and mean angle of wave approach is used in terms of external boundary conditions for the SWAN wave model, which is set up for the western Black Sea shelf at 4km resolution. The same model set up on about 400m resolution is nested to the first SWAN run. In this case the SWAN 2D spectral output provides boundary conditions for the high-resolution model run. The models are implemented for a

  15. Landward Distribution of Wave Overtopping for Rubble Mound Breakwaters

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Burcharth, Hans F.

    2006-01-01

    Overtopping data from seven model test projects has been analyzed with respect to the landward spatial distribution of the overtopping discharge. In total more than 1000 overtopping tests have been analysed and a formula derived for prediction of the landward distribution of overtopping behind...... rubble mound structures with a super structure. The analysis led to the conclusion that although the overtopping discharge, for identical wave heights, decreases with increasing wave steepness, then the maximum travel distance increases with increasing wave steepness....

  16. DFT study on oxidation of HS(CH2) m SH ( m = 1-8) in oxidative desulfurization

    Science.gov (United States)

    Song, Y. Z.; Song, J. J.; Zhao, T. T.; Chen, C. Y.; He, M.; Du, J.

    2016-06-01

    Density functional theory was employed for calculation of HS(CH2) m SH ( m = 1-8) and its derivatives at B3LYP method at 6-31++g ( d, p) level. Using eigenvalues of LUMO and HOMO for HS(CH2) m SH, the standard electrode potentials were estimated by a stepwise multiple regression techniques (MLR), and obtained as E° = 1.500 + 7.167 × 10-3 HOMO-0.229 LUMO with high correlation coefficients of 0.973 and F values of 43.973.

  17. Fe(II)/Cu(II) interaction on goethite stimulated by an iron-reducing bacteria Aeromonas Hydrophila HS01 under anaerobic conditions.

    Science.gov (United States)

    Tao, Liang; Zhu, Zhen-Ke; Li, Fang-Bai; Wang, Shan-Li

    2017-11-01

    Copper is a trace element essential for living creatures, but copper content in soil should be controlled, as it is toxic. The physical-chemical-biological features of Cu in soil have a significant correlation with the Fe(II)/Cu(II) interaction in soil. Of significant interest to the current study is the effect of Fe(II)/Cu(II) interaction conducted on goethite under anaerobic conditions stimulated by HS01 (a dissimilatory iron reduction (DIR) microbial). The following four treatments were designed: HS01 with α-FeOOH and Cu(II) (T1), HS01 with α-FeOOH (T2), HS01 with Cu(II) (T3), and α-FeOOH with Cu(II) (T4). HS01 presents a negligible impact on copper species transformation (T3), whereas the presence of α-FeOOH significantly enhanced copper aging contributing to the DIR effect (T1). Moreover, the violent reaction between adsorbed Fe(II) and Cu(II) leads to the decreased concentration of the active Fe(II) species (T1), further inhibiting reactions between Fe(II) and iron (hydr)oxides and decelerating the phase transformation of iron (hydr)oxides (T1). From this study, the effects of the Fe(II)/Cu(II) interaction on goethite under anaerobic conditions by HS01 are presented in three aspects: (1) the accelerating effect of copper aging, (2) the reductive transformation of copper, and (3) the inhibition effect of the phase transformation of iron (hydr)oxides. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Collective dipole motion in highly excited (272)Hs (Z=108) nuclei

    NARCIS (Netherlands)

    Tveter, TS; Gaardhoje, JJ; Maj, A; Ramsay, T; Atac, A; Bacelar, J; Bracco, A; Buda, A; Camera, F; Herskind, B; Korten, W; Krolas, W; Menthe, A; Million, B; Nifenecker, H; Pignanelli, M; Pinston, JA; vanderPloeg, H; Schussler, F; Sletten, G

    1996-01-01

    The heavy nucleus (272)(108)Hs (Z = 108) and its evaporation daughters were produced using the reaction Th-232(Ar-40, gamma xn) with beam energies 10.5 and 15.0 MeV/A. The giant dipole resonance gamma radiation from the hot composite system prior to fission has been isolated using a differential

  19. Inertia-gravity waves in the troposphere and lower stratosphere associated with a jet stream exit region

    Directory of Open Access Journals (Sweden)

    L. Thomas

    Full Text Available Radar measurements at Aberystwyth (52.4° N, 4.1° W of winds at tropospheric and lower stratospheric heights are shown for 12-13 March 1994 in a region of highly curved flow, downstream of the jet maximum. The perturbations of horizontal velocity have comparable amplitudes in the troposphere and lower stratosphere with downward and upward phase propagation, respectively, in these two height regions. The sense of rotation with increasing height in hodographs of horizontal perturbation velocity derived for hourly intervals show downwards propagation of energy in the troposphere and upward propagation in the lower stratosphere with vertical wavelengths of 1.7 to 2.3 km. The results indicate inertia-gravity waves propagating in a direction similar to that of the jet stream but at smaller velocities. Some of the features observed contrast with those of previous observations of inertia-gravity waves propagating transverse to the jet stream. The interpretation of the hodographs to derive wave parameters has taken account of the vertical shear of the background wind transverse to the direction of wave propagation.

    Key words. Meteorology and atmospheric dynamics (mesoscale meteorology; middle atmosphere dynamics; waves and tides

  20. 3-O-sulfated heparan sulfate recognized by the antibody HS4C3 contributes [corrected] to the differentiation of mouse embryonic stem cells via fas signaling.

    Directory of Open Access Journals (Sweden)

    Kazumi Hirano

    Full Text Available Maintenance of self-renewal and pluripotency in mouse embryonic stem cells (mESCs is regulated by the balance between several extrinsic signaling pathways. Recently, we demonstrated that heparan sulfate (HS chains play important roles in the maintenance and differentiation of mESCs by regulating extrinsic signaling. Sulfated HS structures are modified by various sulfotransferases during development. However, the significance of specific HS structures during development remains unclear. Here, we show that 3-O-sulfated HS structures synthesized by HS 3-O-sulfotransferases (3OSTs and recognized by the antibody HS4C3 increase during differentiation of mESCs. Furthermore, expression of Fas on the cell surface of the differentiated cells also increased. Overexpression of the HS4C3-binding epitope in mESCs induced apoptosis and spontaneous differentiation even in the presence of LIF and serum. These data showed that the HS4C3-binding epitope was required for differentiation of mESCs. Up-regulation of the HS4C3-binding epitope resulted in the recruitment of Fas from the cytoplasm to lipid rafts on the cell surface followed by activation of Fas signaling. Indeed, the HS4C3-binding epitope interacted with a region that included the heparin-binding domain (KLRRRVH of Fas. Reduced self-renewal capability in cells overexpressing 3OST resulted from the degradation of Nanog by activated caspase-3, which is downstream of Fas signaling, and was rescued by the inhibition of Fas signaling. We also found that knockdown of 3OST and inhibition of Fas signaling reduced the potential for differentiation into the three germ layers during embryoid body formation. This is the first demonstration that activation of Fas signaling is mediated by an increase in the HS4C3-binding epitope and indicates a novel signaling pathway for differentiation in mESCs.

  1. 3-O-sulfated heparan sulfate recognized by the antibody HS4C3 contributes [corrected] to the differentiation of mouse embryonic stem cells via fas signaling.

    Science.gov (United States)

    Hirano, Kazumi; Sasaki, Norihiko; Ichimiya, Tomomi; Miura, Taichi; Van Kuppevelt, Toin H; Nishihara, Shoko

    2012-01-01

    Maintenance of self-renewal and pluripotency in mouse embryonic stem cells (mESCs) is regulated by the balance between several extrinsic signaling pathways. Recently, we demonstrated that heparan sulfate (HS) chains play important roles in the maintenance and differentiation of mESCs by regulating extrinsic signaling. Sulfated HS structures are modified by various sulfotransferases during development. However, the significance of specific HS structures during development remains unclear. Here, we show that 3-O-sulfated HS structures synthesized by HS 3-O-sulfotransferases (3OSTs) and recognized by the antibody HS4C3 increase during differentiation of mESCs. Furthermore, expression of Fas on the cell surface of the differentiated cells also increased. Overexpression of the HS4C3-binding epitope in mESCs induced apoptosis and spontaneous differentiation even in the presence of LIF and serum. These data showed that the HS4C3-binding epitope was required for differentiation of mESCs. Up-regulation of the HS4C3-binding epitope resulted in the recruitment of Fas from the cytoplasm to lipid rafts on the cell surface followed by activation of Fas signaling. Indeed, the HS4C3-binding epitope interacted with a region that included the heparin-binding domain (KLRRRVH) of Fas. Reduced self-renewal capability in cells overexpressing 3OST resulted from the degradation of Nanog by activated caspase-3, which is downstream of Fas signaling, and was rescued by the inhibition of Fas signaling. We also found that knockdown of 3OST and inhibition of Fas signaling reduced the potential for differentiation into the three germ layers during embryoid body formation. This is the first demonstration that activation of Fas signaling is mediated by an increase in the HS4C3-binding epitope and indicates a novel signaling pathway for differentiation in mESCs.

  2. Social inequalities in height: persisting differences today depend upon height of the parents.

    Directory of Open Access Journals (Sweden)

    Bruna Galobardes

    Full Text Available Substantial increases in height have occurred concurrently with economic development in most populations during the last century. In high-income countries, environmental exposures that can limit genetic growth potential appear to have lessened, and variation in height by socioeconomic position may have diminished. The objective of this study is to investigate inequalities in height in a cohort of children born in the early 1990s in England, and to evaluate which factors might explain any identified inequalities.12,830 children from The Avon Longitudinal Study of Parents and Children (ALSPAC, a population based cohort from birth to about 11.5 years of age, were used in this analysis. Gender- and age-specific z-scores of height at different ages were used as outcome variables. Multilevel models were used to take into account the repeated measures of height and to analyze gender- and age-specific relative changes in height from birth to 11.5 years. Maternal education was the main exposure variable used to examine socioeconomic inequalities. The roles of parental and family characteristics in explaining any observed differences between maternal education and child height were investigated. Children whose mothers had the highest education compared to those with none or a basic level of education, were 0.39 cm longer at birth (95% CI: 0.30 to 0.48. These differences persisted and at 11.5 years the height difference was 1.4 cm (95% CI: 1.07 to 1.74. Several other factors were related to offspring height, but few changed the relationship with maternal education. The one exception was mid-parental height, which fully accounted for the maternal educational differences in offspring height.In a cohort of children born in the 1990s, mothers with higher education gave birth to taller boys and girls. Although height differences were small they persisted throughout childhood. Maternal and paternal height fully explained these differences.

  3. Analysis of the impacts of Wave Energy Converter arrays on the nearshore wave climate in the Pacific Northwest

    Science.gov (United States)

    O'Dea, A.; Haller, M. C.

    2013-12-01

    As concerns over the use of fossil fuels increase, more and more effort is being put into the search for renewable and reliable sources of energy. Developments in ocean technologies have made the extraction of wave energy a promising alternative. Commercial exploitation of wave energy would require the deployment of arrays of Wave Energy Converters (WECs) that include several to hundreds of individual devices. Interactions between WECs and ocean waves result in both near-field and far-field changes in the incident wave field, including a significant decrease in wave height and a redirection of waves in the lee of the array, referred to as the wave shadow. Nearshore wave height and direction are directly related to the wave radiation stresses that drive longshore currents, rip currents and nearshore sediment transport, which suggests that significant far-field changes in the wave field due to WEC arrays could have an impact on littoral processes. The goal of this study is to investigate the changes in nearshore wave conditions and radiation stress forcing as a result of an offshore array of point-absorber type WECs using a nested SWAN model, and to determine how array size, configuration, spacing and distance from shore influence these changes. The two sites of interest are the Northwest National Marine Renewable Energy Center (NNMREC) test sites off the coast of Newport Oregon, the North Energy Test Site (NETS) and the South Energy Test Site (SETS). NETS and SETS are permitted wave energy test sites located approximately 4 km and 10 km offshore, respectively. Twenty array configurations are simulated, including 5, 10, 25, 50 and 100 devices in two and three staggered rows in both closely spaced (three times the WEC diameter) and widely spaced (ten times the WEC diameter) arrays. Daily offshore wave spectra are obtained from a regional WAVEWATCH III hindcast for 2011, which are then propagated across the continental shelf using SWAN. Arrays are represented in SWAN

  4. Does cooperativity influence the lifetime of the photo-induced HS state?

    International Nuclear Information System (INIS)

    Letard, Jean-Francois; Costa, Jose Sanchez; Marcen, Silvia; Carbonera, Chiara; Desplanches, Cedric; Kobayashi, Atsushi; Daro, Nathalie; Guionneau, Philippe; Ader, Jean-Pierre

    2005-01-01

    We have first recalled the T(LIESST) procedure which consists to determine the temperature above which the photo-magnetic effect is erased. In addition we have selected to series of iron(II) spin crossover complexes, the [Fe(PM-L) 2 (NCS) 2 ] and [Fe(bpp) 2 ]X 2 ·nH 2 O families, to analyse the influence of the cooperativity on the stability of the photo-induced HS state. Some of these complexes exhibit gradual thermal spin crossover behaviours while some others undergo an abrupt thermal transition, with and without hysteresis. Interestingly, whatever the cooperativity effect on the thermal spin crossover transition, the lifetime of the metastable state of all these derivates remains governed by the T(LIESST) = T 0 - 0.31 T 1/2 relation. Finally, we have investigated the magnetic and the photomagnetic properties of a [Fe(bpp) 2 ]-Nafion film. Once more the role of the cooperativity on the stability of the photoinduced HS state appears minor. Conversely, the influence of the nature and the geometry of the inner coordination sphere appears preponderant

  5. Detection significance of serum hs-CRP and ALB in premature infants with early infections%血清hs-CRP与ALB检测对早产儿早发感染的临床意义

    Institute of Scientific and Technical Information of China (English)

    王陈裕; 何海雅; 汤梦倩; 杜姗; 金燕芬; 洪艳; 胡荣全

    2017-01-01

    OBJECTIVE To explore the clinical diagnostic values of serum high sensitivity C-reactive protein (hs-CRP) and albumin (ALB) in premature infants with early infections .METHODS A total of 156 cases of premature infants hospitalized from Feb .2015 to Mar .2016 in our hospital for treatment were selected as the research ob-jects ,and were divided into infection group (74 cases) and non-infected group (82 cases) according to the infection status of premature infants .Blood samples of premature infants were collected for detection of white blood cell count (WBC) ,platelet count (PLT) and hs-CRP and ALB at 24h after the infants admitted into the neonatal in-tensive care unit .RESULTS There were 74 cases of premature infants had infections in the 156 cases of patients , and the infection rate was 47 .44% ,which was mainly pneumonia .Totally 90 strains of pathogens were detected in infected premature infants ,including 18 strains of gram-negative bacteria accounting for 20 .00% ,mainly Esche-richia coli ,and 65 strains of gram-positive bacteria accounting for 72 .22% ,mainly Staphylococcus aurous and Staphylococcus epidermises .The white blood cell count ,platelet count and albumin of infection group were (13 . 28 ± 4 .20)× 109/L ,(238 .30 ± 41 .02)× 109/L and (26 .54 ± 10 .25)g/L ,which were lower than (17 .10 ± 5 .12) × 109/L ,(261 .05 ± 42 .06) × 109/L and (29 .64 ± 12 .24)g/L in non-infected group ,and hs-CRP and ALB in in-fection group at 24h and 48h were (2 .38 ± 0 .49)mg/L and (22 .03 ± 9 .36)mg/L ,which were significantly higher than (1 .02 ± 0 .21)mg/L and (17 .65 ± 8 .67) mg/L in non-infected group (P<0 .05) .There were 3 ca-ses died in infection group after 48h ,and the mortality rate was 4 .05% .CONCLUSION Serum hs-CRP and ALB can be used as effective clinical diagnostic indexes of early infection in premature infants ,and hs-CRP and ALB of infants within 24 hours of admission to the NICU can greatly improve the diagnostic sensitivity .%

  6. Prediction of the shape of inline wave force and free surface elevation using First Order Reliability Method (FORM)

    DEFF Research Database (Denmark)

    Ghadirian, Amin; Bredmose, Henrik; Schløer, Signe

    2017-01-01

    theory, that is, the most likely time history of inline force around a force peak of given value. The results of FORM and NewForce are linearly identical and show only minor deviations at second order. The FORM results are then compared to wave averaged measurements of the same criteria for crest height......In design of substructures for offshore wind turbines, the extreme wave loads which are of interest in Ultimate Limit States are often estimated by choosing extreme events from linear random sea states and replacing them by either stream function wave theory or the NewWave theory of a certain...... design wave height. As these wave theories super from limitations such as symmetry around the crest, other methods to estimate the wave loads are needed. In the present paper, the First Order Reliability Method, FORM, is used systematically to estimate the most likely extreme wave shapes. Two parameters...

  7. Generation of intermittent gravitocapillary waves via parametric forcing

    Science.gov (United States)

    Castillo, Gustavo; Falcón, Claudio

    2018-04-01

    We report on the generation of an intermittent wave field driven by a horizontally moving wave maker interacting with Faraday waves. The spectrum of the local gravitocapillary surface wave fluctuations displays a power law in frequency for a wide range of forcing parameters. We compute the probability density function of the local surface height increments, which show that they change strongly across time scales. The structure functions of these increments are shown to display power laws as a function of the time lag, with exponents that are nonlinear functions of the order of the structure function. We argue that the origin of this scale-invariant intermittent spectrum is the Faraday wave pattern breakup due to its advection by the propagating gravity waves. Finally, some interpretations are proposed to explain the appearance of this intermittent spectrum.

  8. Comparison of solutol HS 15, Cremophor EL and novel ethoxylated fatty acid surfactants as multidrug resistance modification agents.

    Science.gov (United States)

    Buckingham, L E; Balasubramanian, M; Emanuele, R M; Clodfelter, K E; Coon, J S

    1995-08-09

    Some well-known fatty acid ester surfactants, e.g., Cremophor EL and Solutol HS 15, are modulators of multidrug resistance in vitro and in vivo. Because they are polydisperse, and their active component(s) have not been identified, the therapeutic potential of such surfactants is unclear. To better define the active components of Solutol HS 15 and to make more potent surfactant multidrug resistance modulators, highly purified C-18 fatty acids were esterified with ethylene oxide at 5-200 molar ratios. Unexpectedly, ethylene oxide esters of pure 12-hydroxy stearic acid, the major components of Solutol HS 15, displayed negligible resistance modification activity compared with Solutol HS 15 itself or to stearic and oleic acid esters synthesized under identical conditions. Since oleic acid esters appeared to have good activity, a series of these compounds was prepared to determine the optimal ethylene oxide/fatty acid ratio. The optimal ratio was found to be 20 mole ethylene oxide: I mole fatty acid, with a steep decline in activity for products made with ratios above and below the optimum. The most active oleic acid ester, designated CRL 1337, was 8.4-fold as potent as Solutol HS 15 and over 19-fold as potent as Cremophor EL in promoting rhodamine 123 accumulation in multidrug-resistant KB 8-5-11 cells in vitro. Our results show that the structure of the hydrophobic domain (fatty acid) of surfactants as well as its hydrophile-lipophile balance are critical in determining the potency of surfactants as reversing agents.

  9. Real Time Wave Forecasting Using Wind Time History and Genetic Programming

    Directory of Open Access Journals (Sweden)

    A.R. Kambekar

    2014-12-01

    Full Text Available The significant wave height and average wave period form an essential input for operational activities in ocean and coastal areas. Such information is important in issuing appropriate warnings to people planning any construction or instillation works in the oceanic environment. Many countries over the world routinely collect wave and wind data through a network of wave rider buoys. The data collecting agencies transmit the resulting information online to their registered users through an internet or a web-based system. Operational wave forecasts in addition to the measured data are also made and supplied online to the users. This paper discusses operational wave forecasting in real time mode at locations where wind rather than wave data are continuously recorded. It is based on the time series modeling and incorporates an artificial intelligence technique of genetic programming. The significant wave height and average wave period values are forecasted over a period of 96 hr in future from the observations of wind speed and directions extending to a similar time scale in the past. Wind measurements made by floating buoys at eight different locations around India over a period varying from 1.5 yr to 9.0 yr were considered. The platform of Matlab and C++ was used to develop a graphical user interface that will extend an internet based user-friendly access of the forecasts to any registered user of the data dissemination authority.

  10. Assimilation of radar altimeter data in numerical wave models: an impact study in two different wave climate regions

    Directory of Open Access Journals (Sweden)

    G. Emmanouil

    2007-03-01

    Full Text Available An operational assimilation system incorporating significant wave height observations in high resolution numerical wave models is studied and evaluated. In particular, altimeter satellite data provided by the European Space Agency (ESA-ENVISAT are assimilated in the wave model WAM which operates in two different wave climate areas: the Mediterranean Sea and the Indian Ocean. The first is a wind-sea dominated area while in the second, swell is the principal part of the sea state, a fact that seriously affects the performance of the assimilation scheme. A detailed study of the different impact is presented and the resulting forecasts are evaluated against available buoy and satellite observations. The corresponding results show a considerable improvement in wave forecasting for the Indian Ocean while in the Mediterranean Sea the assimilation impact is restricted to isolated areas.

  11. Wave groupiness variations in the nearshore

    Science.gov (United States)

    List, J.H.

    1991-01-01

    This paper proposes a new definition of the groupiness factor, GF, based on the envelope of the incident-wave time series. It is shown that an envelope-based GF has several important advantages over the SIWEH-based groupiness factor, including objective criteria for determining the accuracy of the envelope function and well-defined numerical limits. Using this new GF, the variability of incident wave groupiness in the field is examined both temporally, in unbroken waves at a fixed location, and spatially, in a cross-shore array through the surf zone. Contrary to previous studies using the SIWEH-based GF, results suggest that incident wave groupiness may not be an independent parameter in unbroken waves; through a wide range of spectral shapes, from swell to storm waves, the groupiness did not vary significantly. As expected, the groupiness decreases rapidly as waves break through the surf zone, although significant wave height variability persists even through a saturated surf zone. The source of this inner surf zone groupiness is not identified; however, this observation implies that models of long wave generation must account for nonsteady radiation stress gradients landward of some narrow zone near the mean breakpoint. ?? 1991.

  12. Clinical significance of measurment of changes of serum IGF-I, hs-CRP levels after treatment in patients with hyperthyroidism and hypothyroidism

    International Nuclear Information System (INIS)

    Zhu Conggang

    2009-01-01

    Objective: To explore the clinical significance of changes of serum IGF-I,hs-CRP levels after treatment in patients with hyperthyroidism and hypothyroidism. Methods: Serum IGF-I, hs-CRP(with RIA), and serum hs-CRP with immuno-turbidity methods levels were determined both before and after treatment in 36 cases of hyperthyroidism 30 cases of hypothyroidism as well as 35 controls. Results: Before treatment, the serum IGF-I levels in patients with hyperthyroidism were significantly higher and the levels in patients with hypothyroidism were significantly lower than those in controls (both P<0.01). After treatment for 3 months,the levels were much corrected, but still remained significantly different from those in controls (P<0.05). Before treatment serum hs-CRP levels in both groups of patients were significantly higher than those in controls (P<0.01), but after treatment,the levels were not much different from those in controls. Conclusion: Serum levels of IGF-I and hs-CRP were closely related to the disease process in patients with hyperthyroidism as well as in patients with hypothyroidism, and were much corrected after trentment.(authors)

  13. Study on Dissipation of Landslide Generated Waves in Different Shape of Reservoirs

    Science.gov (United States)

    An, Y.; Liu, Q.

    2017-12-01

    The landslide generated waves are major risks for many reservoirs located in mountainous areas. As the initial wave is often very huge (e.g. 30m of the height in Xiaowan event, 2009, China), the dissipation of the wave, which is closely connected with the shape of the reservoir (e.g. channel type vs. lake type), is a crucial factor in risk estimation and prevention. While even for channel type reservoir, the wave damping also varies a lot due to details of the shape such as branches and turnings. Focusing on the influence of this shape details on the wave damping in channel type reservoir, we numerically studied two landslide generated wave events with both a triangle shape of the cross section but different longitudinal shape configurations (Xiaowan event in 2009 and an assuming event in real topography). The two-dimensional Saint-Venant equation and dry-wet boundary treatment method are used to simulate the wave generation and propagation processes. The simulation is based on an open source code called `Basilisk' and the adaptive mesh refinement technique is used to achieve enough precision with affordable computational resources. The sensitivity of the parameters representing bed drag and the vortex viscosity is discussed. We found that the damping is relatively not sensitive to the bed drag coefficient, which is natural as the water depth is large compared with wave height. While the vortex viscosity needs to be chosen carefully as it is related to cross sectional velocity distribution. It is also found that the longitudinal shape, i.e. the number of turning points and branches, is the key factor influencing the wave damping. The wave height at the far field could be only one seventh comparing with the initial wave in the case with complex longitudinal shape, while the damping is much weaker in the straight channel case. We guess that this phenomenon is due to the increasing sloshing at these abruptly changed positions. This work could provide a deeper

  14. Waves in Gulf of Mannar and Palk Bay around Dhanushkodi, Tamil Nadu, India

    Digital Repository Service at National Institute of Oceanography (India)

    Gowthaman, R.; SanilKumar, V.; Dwarakish, G.S.; Mohan, S.S.; Singh, J.; AshokKumar, K.

    ., Wave characteris- tics off Visakhapatnam coast during a cyclone. Curr. Sci., 2004, 86, 1524–1529. 3. Nayak, B. U., Chandramohan, P. and Sakhardande, R. K., Sea- sonal distribution of wave heights off Yanam on the east coast of India. Indian J. Inst...

  15. On the pressure field of nonlinear standing water waves

    Science.gov (United States)

    Schwartz, L. W.

    1980-01-01

    The pressure field produced by two dimensional nonlinear time and space periodic standing waves was calculated as a series expansion in the wave height. The high order series was summed by the use of Pade approximants. Calculations included the pressure variation at great depth, which was considered to be a likely cause of microseismic activity, and the pressure distribution on a vertical barrier or breakwater.

  16. Crossing seas and occurrence of rogue waves

    Science.gov (United States)

    Bitner-Gregersen, Elzbieta; Toffoli, Alessandro

    2017-04-01

    The study is addressing crossing wave systems which may lead to formation of rogue waves. Onorato et al. (2006, 2010) have shown using the Nonlinear Schr?dringer (NLS) equations that the modulational instability and rogue waves can be triggered by a peculiar form of directional sea state, where two identical, crossing, narrow-banded random wave systems interact with each other. Such results have been underpinned by numerical simulations of the Euler equations solved with a Higher Order Spectral Method (HOSM) and experimental observations (Toffoli et al., 2011). They substantiate a dependence of the angle between the mean directions of propagation of the two crossing wave systems, with a maximum rogue wave probability for angles of approximately 40 degrees. Such an unusual sea state of two almost identical wave systems (approximately the same significant wave height and mean frequency) with high steepness and different directions was observed during the accident to the cruise ship Louis Majesty (Cavaleri et al. 2012). Occurrence of wind sea and swell having almost the same spectral period and significant wave height and crossing at the angle 40o low and intermediate wave conditions. They have not been found in a location off coast of Australia and Nigeria. There are some indications that in the future climate we may expect an increase number of occurrence of rogue-prone crossing sea states in some ocean regions An adopted partitioning procedure of a wave spectrum will impact the results. References Bitner-Gregersen, E.M. and Toffoli, A., 2014. Probability of occurrence of rogue sea states and consequences for design of marine structures. Special Issue of Ocean Dynamics, ISSN 1616-7341, 64(10), DOI 10.1007/s10236-014-0753-2. Cavaleri, L., Bertotti, L., Torrisi, L. Bitner-Gregersen, E., Serio, M. and Onorato, M., 2012. Rogue Waves in Crossing Seas: The Louis Majesty accident. J. Geophysical Research, 117, C00J10, doi:10.1029/2012JC007923 Onorato, M., A. Osborne, A

  17. Final height in survivors of childhood cancer compared with Height Standard Deviation Scores at diagnosis

    NARCIS (Netherlands)

    Knijnenburg, S. L.; Raemaekers, S.; van den Berg, H.; van Dijk, I. W. E. M.; Lieverst, J. A.; van der Pal, H. J.; Jaspers, M. W. M.; Caron, H. N.; Kremer, L. C.; van Santen, H. M.

    2013-01-01

    Our study aimed to evaluate final height in a cohort of Dutch childhood cancer survivors (CCS) and assess possible determinants of final height, including height at diagnosis. We calculated standard deviation scores (SDS) for height at initial cancer diagnosis and height in adulthood in a cohort of

  18. Exploring the smallest active fragment of HsQSOX1b and finding a highly efficient oxidative engine.

    Directory of Open Access Journals (Sweden)

    Wenyun Zheng

    Full Text Available Human quiescin-sulfhydryl oxidase 1 isoform b (HsQSOX1b is a highly efficient, multiple-domain enzyme that directly inserts disulfide bonds into client protein. However, previous studies have focused mainly on the catalytic activity of the whole protein rather than its domain structure. In this research, we dissected the structure and function of HsQSOX1b and explored its mechanism as a highly efficient sulfhydryl oxidase by analyzing the truncated variants. The results showed that the first HsQSOX1b thioredoxin domain was essential for thiol oxidase activity. The smallest active fragment (SAQ was identified to consist of a helix-rich region (HRR and an essential for respiration and viability/augmenter of liver regeneration (ERV/ALR domain, which remained highly active to oxidize an artificial non-thiol substrate but not small molecular and protein thiols. Our study clearly demonstrated that SAQ is a highly efficient oxidative engine, which shows high efficiency in the de novo disulfide formation and oxygen reduction and that this more efficient oxidative engine is necessary for the highly efficient catalysis of QSOXs compared to Erv1 and Erv2. This study will help address the roles of different HsQSOX1b domains in de novo disulfide formation and encourage the engineering of more efficient QSOX variants for the in vitro folding of disulfide-containing proteins.

  19. Detection of traveling ionospheric disturbances induced by atmospheric gravity waves using the global positioning system

    Science.gov (United States)

    Bassiri, Sassan; Hajj, George A.

    1993-01-01

    Natural and man-made events like earthquakes and nuclear explosions launch atmospheric gravity waves (AGW) into the atmosphere. Since the particle density decreases exponentially with height, the gravity waves increase exponentially in amplitude as they propagate toward the upper atmosphere and ionosphere. As atmospheric gravity waves approach the ionospheric heights, the neutral particles carried by gravity waves collide with electrons and ions, setting these particles in motion. This motion of charged particles manifests itself by wave-like fluctuations and disturbances that are known as traveling ionospheric disturbances (TID). The perturbation in the total electron content due to TID's is derived analytically from first principles. Using the tilted dipole magnetic field approximation and a Chapman layer distribution for the electron density, the variations of the total electron content versus the line-of-sight direction are numerically analyzed. The temporal variation associated with the total electron content measurements due to AGW's can be used as a means of detecting characteristics of the gravity waves. As an example, detection of tsunami generated earthquakes from their associated atmospheric gravity waves using the Global Positioning System is simulated.

  20. Clinical significance of determination of changes of serum hs-CRP, sICAM-1 and TNF-α levels in patients with gestational diabetes mellitus

    International Nuclear Information System (INIS)

    Yu Qiuyue

    2009-01-01

    Objective: To study the relationship between changes of serum sensitive C-reactive protein (hs-CRP), tumor necrosis factor-alpha (TNF-α) and soluble intercellular adhesion molecule-1 (sICAM-1) levels and development of the disease in patients with gestational diabetes mellitus(GDM). Methods: Serum levels of TNF-α and sICAM-1(with RIA) and hs-CRP(with immunoturbidimetry) were measured in 30 patients with GDM and 30 normal pregnant women as controls. Results: The serum hs-CRP, sICAM-1 and TNF-α contents in the patients with GDM were all significantly higher than those in normal pregnant women (all P<0.01).The serum hs-CRP levels were mutually positivety correlated with TNF-α and sICAM-1 levels (r=0.6097, 0.7213, all P<0.01). Conclusion: Determination of changes of serum hs-CRP, TNF-α and sICAM-1 levels in patients with gestational diabetes mellitus would be helpful for outcome prediction. (authors)

  1. Optimization of bottom-hinged flap-type wave energy converter for a specific wave rose

    Science.gov (United States)

    Behzad, Hamed; Panahi, Roozbeh

    2017-06-01

    In this paper, we conducted a numerical analysis on the bottom-hinged flap-type Wave Energy Convertor (WEC). The basic model, implemented through the study using ANSYS-AQWA, has been validated by a three-dimensional physical model of a pitching vertical cylinder. Then, a systematic parametric assessment has been performed on stiffness, damping, and WEC direction against an incoming wave rose, resulting in an optimized flap-type WEC for a specific spot in the Persian Gulf. Here, stiffness is tuned to have a near-resonance condition considering the wave rose, while damping is modified to capture the highest energy for each device direction. Moreover, such sets of specifications have been checked at different directions to present the best combination of stiffness, damping, and device heading. It has been shown that for a real condition, including different wave heights, periods, and directions, it is very important to implement the methodology introduced here to guarantee device performance.

  2. Long-term evolution of sand waves in the Marsdiep inlet. II: Relation to hydrodynamics

    Science.gov (United States)

    Buijsman, Maarten C.; Ridderinkhof, Herman

    2008-05-01

    A discussion is presented about the mechanisms that govern the spatial and seasonal variability in sand-wave height and migration speed in the 4 km wide Marsdiep tidal inlet, the Netherlands. Since 1998, current velocities and water depths have been recorded with an ADCP that is mounted under the ferry 'Schulpengat'. In this paper, the current measurements were used to explain the sand-wave observations presented in Buijsman and Ridderinkhof [this issue. Long-term evolution of sand waves in the Marsdiep inlet. I: high-resolution observations. Continental Shelf Research, doi: 10.1016/j.csr.2007.10.011]. Across nearly the entire inlet, the sand waves migrate in the flood direction. In the flood-dominated southern part of the inlet, the 'measured' (i.e. based on sand-wave shape and migration speed) and predicted bedload transport agree in direction, magnitude, and trends, whereas in the ebb-dominated northern part the predicted bedload and suspended load transport is opposite to the sand-wave migration. In the southern part, 55% of the bedload transport is due to tidal asymmetries and 45% due to residual currents. In addition to the well-known tidal asymmetries, asymmetries that arise from the interaction of M2 and its overtides with S2 and its compound tides are also important. It is hypothesised that in the northern part of the inlet the advection of suspended sand and lag effects govern the sand-wave migration. The relative importance of suspended load transport also explains why the sand waves have smaller lee-slope angles, are smaller, more rounded, and more three-dimensional in the northern half of the inlet. The sand waves in this part of the inlet feature the largest seasonal variability in height and migration speed. This seasonal variability may be attributed to the tides or a seasonal fluctuation in fall velocity. In both cases sediment transport is enhanced in winter, increasing sand-wave migration and decreasing sand-wave height. The influence of storms

  3. Height premium for job performance.

    Science.gov (United States)

    Kim, Tae Hyun; Han, Euna

    2017-08-01

    This study assessed the relationship of height with wages, using the 1998 and 2012 Korean Labor and Income Panel Study data. The key independent variable was height measured in centimeters, which was included as a series of dummy indicators of height per 5cm span (wages to assess the heterogeneity in the height-wage relationship, across the conditional distribution of monthly wages. We found a non-linear relationship of height with monthly wages. For men, the magnitude of the height wage premium was overall larger at the upper quantile of the conditional distribution of log monthly wages than at the median to low quantile, particularly in professional and semi-professional occupations. The height-wage premium was also larger at the 90th quantile for self-employed women and salaried men. Our findings add a global dimension to the existing evidence on height-wage premium, demonstrating non-linearity in the association between height and wages and heterogeneous changes in the dispersion and direction of the association between height and wages, by wage level. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Wave forecasting and monitoring during very severe cyclone Phailin in the Bay of Bengal.

    Digital Repository Service at National Institute of Oceanography (India)

    Nair, T.M.B; Remya, P.G.; Harikumar, R.; Sandhya, K.G.; Sirisha, P.; Srinivas, K.; Nagaraju, C.; Nherakkol, A.; KrishnaPrasad, B.; Jeyakumar, C.; Kaviyazhahu, K.; Hithin, N.K.; Kumari, R.; SanilKumar, V.; RameshKumar, M.; Shenoi, S.S.C.; Nayak, S.

    Wave fields, both measured and forecast during the very severe cyclone Phailin, are discussed in this communication. Waves having maximum height of 13.54 m were recorded at Gopalpur, the landfall point of the cyclone. The forecast and observed...

  5. The impact of diurnal fasting during Ramadan on the lipid profile, hs-CRP, and serum leptin in stable cardiac patients.

    Science.gov (United States)

    Khafaji, Hadi Abdul Ridha Hadi; Bener, Abdulbari; Osman, Mohammed; Al Merri, Ajayeb; Al Suwaidi, Jassim

    2012-01-01

    To study the effect of strict prolonged fasting on lipid profile, serum leptin, and high- sensitivity C-reactive protein (hs-CRP) in patients with different stable cardiac illnesses and look for associated new cardiac events and any correlation between entire variables. A total of 56 patients of different stable cardiac illnesses were followed in our cardiology outpatient for 3 months. Data concerning their ability to fast were collected: New York Heart Association class of congestive cardiac failure, angina class, previous myocardial infarction, previous coronary artery bypass graft, percutaneous coronary intervention, severity of valvular lesion, metallic prosthetic valve, and traditional risk factors (diabetes mellitus, insulin requirement, hypertension, hypercholesterolemia, smoking habit, and obesity). Detailed clinical examination and electrocardiography were performed in all patients in three consecutive visits before, during, and after Ramadan. Echocardiographic and angiographic findings and medication plans were collected from patient records. Lipid profile, serum leptin, and hs-CRP were assessed before, during, and after Ramadan. All patients fasted during Ramadan: 80.4% were male, 67.9% were aged >50 years, 71.4% had no change in their symptoms during fasting while 28.6% felt better. No patient has deteriorated. 91.1% of the patients were compliant with medicine during Ramadan, 73.2% after. 89.3% were compliant with diet during Ramadan with no significant change in body weight in the follow-up period. No cardiac or noncardiac morbidity or mortality was reported. High- density lipoprotein-cholesterol (HDL-C) decreased significantly during compared to before fasting (P = 0.012). Low-density lipoprotein-cholesterol (LDL-C) significantly increased during compared to before fasting (P = 0.022). No statistically significant changes were observed in total cholesterol (TC), triglycerides (TG), serum leptin, or hs-CRP. Significant correlation was observed between

  6. Clinical significance of measurement of changes of serum hs-CRP, IL-6, IL-8 M-CSF levels after treatment in patients with endometriosis

    International Nuclear Information System (INIS)

    Chen Xiaochao; Zhou Dongxia; Zhang Limin; Liu Hongshu

    2008-01-01

    Objective: To explore the significance of changes of serum hs-CRP, IL-6, IL-8 and M-CSF levels after treatment in patients with endometriosis. Methods: Serum IL-6, IL-8, M -CSF(with RIA), hs-CRP(with immuneturbidity method)levels were determined in 33 patients with endometriosis both before and after treatment as well as in 35 controls. Results: Before treatment, the serum hs-CRP, IL-6, IL-8 and M-CSF levels were significantly higher in the patients than those in controls (P 0.05). Conclusion: Detection of serum hs-CRP, IL-6, IL-8 and M-CSF levels might reflect the progress of diseases in patients with endometriosis. (authors)

  7. Streptomyces flavogriseus HS1: isolation and characterization of extracellular proteases and their compatibility with laundry detergents.

    Science.gov (United States)

    Ghorbel, Sofiane; Kammoun, Maher; Soltana, Hala; Nasri, Moncef; Hmidet, Noomen

    2014-01-01

    The present study describes the isolation of a new protease producing Streptomyces strain HS1 and the biochemical characterization of the secreted proteases. By sequencing of its noted 16S rDNA, HS1 strain was found to have a 100% identity with Streptomyces flavogriseus. The highest protease production was found using FermII media. In these conditions maximum protease production (99 U/mL) was obtained after 96 h incubation at 30°C and 150 rpm. HS1 strain produced at least five proteases as revealed by zymogram technique. The enzyme preparation exhibited activity over a broad range of pH (5-11) and temperature (25-70°C). Optimum activity was observed at a pH of 7.0 and a temperature of 50°C. Proteolytic activity was significantly unaffected by Ca(2+) and Mg(2+). EDTA and PMSF highly decreased the original activity. The crude extracellular proteases showed high stability when used as a detergent additive. These properties offer an interesting potential for enzymatic hydrolysis at the industrial level.

  8. Systems and methods for wave energy conversion

    Science.gov (United States)

    MacDonald, Daniel G.; Cantara, Justin; Nathan, Craig; Lopes, Amy M.; Green, Brandon E.

    2017-02-28

    Systems for wave energy conversion that have components that can survive the harsh marine environment and that can be attached to fixed structures, such as a pier, and having the ability to naturally adjust for tidal height and methods for their use are presented.

  9. Waves in the nearshore waters of northern Arabian Sea during the summer monsoon

    Digital Repository Service at National Institute of Oceanography (India)

    SanilKumar, V.; Singh, J.; Pednekar, P.S.; Gowthaman, R.

    are provided by the NOAA-CIRES Climate Diagnostics Center, Boulder, Colarado at http://www.cdc.noaa.gov/. 3. Results 3.1 Wave height To identify the swell components from the measured data, the locally generated waves and the swell are separated. H m0...

  10. Characterization of microchannel anechoic corners formed by surface acoustic waves

    Science.gov (United States)

    Destgeer, Ghulam; Alam, Ashar; Ahmed, Husnain; Park, Jinsoo; Jung, Jin Ho; Park, Kwangseok; Sung, Hyung Jin

    2018-02-01

    Surface acoustic waves (SAWs) generated in a piezoelectric substrate couple with a liquid according to Snell's law such that a compressional acoustic wave propagates obliquely at a Rayleigh angle ( θ t) inside the microchannel to form a region devoid of a direct acoustic field, which is termed a microchannel anechoic corner (MAC). In the present study, we used microchannels with various heights and widths to characterize the width of the MAC region formed by a single travelling SAW. The attenuation of high-frequency SAWs produced a strong acoustic streaming flow that moved the particles in and out of the MAC region, whereas reflections of the acoustic waves within the microchannel resulted in standing acoustic waves that trapped particles at acoustic pressure nodes located within or outside of the MAC region. A range of actuation frequencies and particle diameters were used to investigate the effects of the acoustic streaming flow and the direct acoustic radiation forces by the travelling as well as standing waves on the particle motion with respect to the MAC region. The width of the MAC ( w c), measured experimentally by tracing the particles, increased with the height of the microchannel ( h m) according to a simple trigonometric equation w c = h m × tan ( θ t ).

  11. Trapped waves on the mid-latitude β-plane

    Science.gov (United States)

    Paldor, Nathan; Sigalov, Andrey

    2008-08-01

    A new type of approximate solutions of the Linearized Shallow Water Equations (LSWE) on the mid-latitude β-plane, zonally propagating trapped waves with Airy-like latitude-dependent amplitude, is constructed in this work, for sufficiently small radius of deformation. In contrast to harmonic Poincare and Rossby waves, these newly found trapped waves vanish fast in the positive half-axis, and their zonal phase speed is larger than that of the corresponding harmonic waves for sufficiently large meridional domains. Our analysis implies that due to the smaller radius of deformation in the ocean compared with that in the atmosphere, the trapped waves are relevant to observations in the ocean whereas harmonic waves typify atmospheric observations. The increase in the zonal phase speed of trapped Rossby waves compared with that of harmonic ones is consistent with recent observations that showed that Sea Surface Height features propagated westwards faster than the phase speed of harmonic Rossby waves.

  12. Wave power for La Isla Bonita

    Energy Technology Data Exchange (ETDEWEB)

    Iglesias, G.; Carballo, R. [Univ. of Santiago de Compostela, Hydraulic Eng., EPS, Campus Univ. s/n, 27002 Lugo (Spain)

    2010-12-15

    The island of La Palma (Spain), dubbed La Isla Bonita for its beauty, is a UNESCO Biosphere Reserve in the Atlantic Ocean. The island's authorities are aiming for energy self-sufficiency based on wave energy and other renewables. In this research its wave resource is investigated using a 44-years hindcast dataset obtained through numerical modelling and validated with wave buoy records. First, its distribution around La Palma is studied. Significant variations are found, with the largest resource occurring off the north and northwest coasts; the northwest presents operational advantages (proximity to a port). Second, the seasonal variations in this area are studied. Wave energy is provided essentially by powerful NNW-NW swells in winter and autumn, by less energetic NNE-N waves in summer and spring. Finally, the resource is characterised in terms of sea states; it is found that the bulk of the energy is provided by waves between 9.5 s and 13.5 s of energy period and 1.5 m and 3.5 m of significant wave height, so the selection of the Wave Energy Converters to be installed should guarantee maximum efficiency in these ranges. (author)

  13. 基于HS-Clustering的风电场机组分组功率预测%Wind Power Forecasting for Clustering Wind Turbines Based on HS-Clustering

    Institute of Scientific and Technical Information of China (English)

    高小力; 张智博; 田启明; 刘永前

    2017-01-01

    为了寻求风电场功率预测精度和计算效率二者的平衡,提出了一种基于霍普金斯统计量与聚类算法(HS-Clustering)的风电场机组分组功率预测方法,该方法将霍普金斯统计量与聚类算法的优势有效结合,采用霍普金斯统计量确定场内机组分组个数,通过聚类算法识别不同机组的相似性将风电场分成不同的机组群,然后对每组机群分别建立功率预测模型,从而叠加得到整场输出功率;另外以实测风速、实测功率及二者组合作为机组分组模型输入,分析其对预测精度的影响程度.实例分析表明基于HS-Clustering的分组预测方法可以显著提高预测精度,同时保证较高的计算效率;风速是影响分组效果的主要因素,对于某些分组模型,功率又可以作为风速的重要补充.%In order to balance the forecast accuracy and computational efficiency, a wind power forecasting method for clustering wind turbines is proposed based on effective combination of Hopkins statistics (HS) and clustering methods, in which Hopkins Statistics is used to determine the clustering number of a wind farm, and wind turbines in a wind farm are clustered into several groups according to the identifying of similar characteristics by clustering method.Then power forecasting model of each clustering group is built separately, whose power output is added to obtain whole power output of the wind farm.In addition, the real-time monitoring wind speed, power output and their combination are taken as the inputs for clustered group model, and their influences on the accuracy of clustering forecast model are analyzed.The case analysis shows that the HS-Clustering based forecasting method can effectively forecast the output power of the whole wind farm with better accuracy and higher computational efficiency, wind speed is the main factor affecting clustering results, and wind power can be regarded as an important additional factor as to certain

  14. Infragravity-wave dynamics in shallow water : energy dissipation and role in sand suspension and transport

    NARCIS (Netherlands)

    de Bakker, A.T.M.|info:eu-repo/dai/nl/371573734

    2016-01-01

    Infragravity waves (20-200 s) receive their energy from sea-swell waves (2-20 s), and are thought to be important to beach erosion during storms, when they can reach up to several meters in height. Numerous studies have observed that on sandy beaches infragravity waves can lose a large part of their

  15. P-HS-SFM: a parallel harmony search algorithm for the reproduction of experimental data in the continuous microscopic crowd dynamic models

    Science.gov (United States)

    Jaber, Khalid Mohammad; Alia, Osama Moh'd.; Shuaib, Mohammed Mahmod

    2018-03-01

    Finding the optimal parameters that can reproduce experimental data (such as the velocity-density relation and the specific flow rate) is a very important component of the validation and calibration of microscopic crowd dynamic models. Heavy computational demand during parameter search is a known limitation that exists in a previously developed model known as the Harmony Search-Based Social Force Model (HS-SFM). In this paper, a parallel-based mechanism is proposed to reduce the computational time and memory resource utilisation required to find these parameters. More specifically, two MATLAB-based multicore techniques (parfor and create independent jobs) using shared memory are developed by taking advantage of the multithreading capabilities of parallel computing, resulting in a new framework called the Parallel Harmony Search-Based Social Force Model (P-HS-SFM). The experimental results show that the parfor-based P-HS-SFM achieved a better computational time of about 26 h, an efficiency improvement of ? 54% and a speedup factor of 2.196 times in comparison with the HS-SFM sequential processor. The performance of the P-HS-SFM using the create independent jobs approach is also comparable to parfor with a computational time of 26.8 h, an efficiency improvement of about 30% and a speedup of 2.137 times.

  16. The Global Signature of Ocean Wave Spectra

    Science.gov (United States)

    Portilla-Yandún, Jesús

    2018-01-01

    A global atlas of ocean wave spectra is developed and presented. The development is based on a new technique for deriving wave spectral statistics, which is applied to the extensive ERA-Interim database from European Centre of Medium-Range Weather Forecasts. Spectral statistics is based on the idea of long-term wave systems, which are unique and distinct at every geographical point. The identification of those wave systems allows their separation from the overall spectrum using the partition technique. Their further characterization is made using standard integrated parameters, which turn out much more meaningful when applied to the individual components than to the total spectrum. The parameters developed include the density distribution of spectral partitions, which is the main descriptor; the identified wave systems; the individual distribution of the characteristic frequencies, directions, wave height, wave age, seasonal variability of wind and waves; return periods derived from extreme value analysis; and crossing-sea probabilities. This information is made available in web format for public use at http://www.modemat.epn.edu.ec/#/nereo. It is found that wave spectral statistics offers the possibility to synthesize data while providing a direct and comprehensive view of the local and regional wave conditions.

  17. Modeling the Buoyancy System of a Wave Energy Power Plant

    DEFF Research Database (Denmark)

    Pedersen, Tom S.; Nielsen, Kirsten M.

    2009-01-01

    A nonlinear dynamic model of the buoyancy system in a wave energy power plant is presented. The plant ("Wave Dragon") is a floating device using the potential energy in overtopping waves to produce power. A water reservoir is placed on top of the WD, and hydro turbines lead the water to the sea...... producing electrical power. Through air chambers it is possible to control the level of the WD. It is important to control the level in order to maximize the power production in proportion to the wave height, here the amount of overtopping water and the amount of potential energy is conflicting...

  18. Height-Deterministic Pushdown Automata

    DEFF Research Database (Denmark)

    Nowotka, Dirk; Srba, Jiri

    2007-01-01

    We define the notion of height-deterministic pushdown automata, a model where for any given input string the stack heights during any (nondeterministic) computation on the input are a priori fixed. Different subclasses of height-deterministic pushdown automata, strictly containing the class...... of regular languages and still closed under boolean language operations, are considered. Several of such language classes have been described in the literature. Here, we suggest a natural and intuitive model that subsumes all the formalisms proposed so far by employing height-deterministic pushdown automata...

  19. Augmented chaos-multiple linear regression approach for prediction of wave parameters

    Directory of Open Access Journals (Sweden)

    M.A. Ghorbani

    2017-06-01

    The inter-comparisons demonstrated that the Chaos-MLR and pure MLR models yield almost the same accuracy in predicting the significant wave heights and the zero-up-crossing wave periods. Whereas, the augmented Chaos-MLR model is performed better results in term of the prediction accuracy vis-a-vis the previous prediction applications of the same case study.

  20. Seasonal and nightly variations of gravity-wave energy density in the middle atmosphere measured by the Purple Crow Lidar

    Directory of Open Access Journals (Sweden)

    R. J. Sica

    2007-11-01

    Full Text Available The Purple Crow Lidar (PCL is a large power-aperture product monostatic Rayleigh-Raman-Sodium-resonance-fluorescence lidar, which has been in operation at the Delaware Observatory (42.9° N, 81.4° W, 237 m elevation near the campus of The University of Western Ontario since 1992. Kinetic-energy density has been calculated from the Rayleigh-scatter system measurements of density fluctuations at temporal-spatial scales relevant for gravity waves, e.g. soundings at 288 m height resolution and 9 min temporal resolution in the upper stratosphere and mesosphere. The seasonal averages from 10 years of measurements show in all seasons some loss of gravity-wave energy in the upper stratosphere. During the equinox periods and summer the measurements are consistent with gravity waves growing in height with little saturation, in agreement with the classic picture of the variations in the height at which gravity waves break given by Lindzen (1981. The mean values compare favourably to previous measurements when computed as nightly averages, but the high temporal-spatial resolution measurements show considerable day-to-day variability. The variability over a night is often extremely large, with typical RMS fluctuations of 50 to 100% at all heights and seasons common. These measurements imply that using a daily or nightly-averaged gravity-wave energy density in numerical models may be highly unrealistic.

  1. Relationship between eruption plume heights and seismic source amplitudes of eruption tremors and explosion events

    Science.gov (United States)

    Mori, A.; Kumagai, H.

    2016-12-01

    It is crucial to analyze and interpret eruption tremors and explosion events for estimating eruption size and understanding eruption phenomena. Kumagai et al. (EPS, 2015) estimated the seismic source amplitudes (As) and cumulative source amplitudes (Is) for eruption tremors and explosion events at Tungurahua, Ecuador, by the amplitude source location (ASL) method based on the assumption of isotropic S-wave radiation in a high-frequency band (5-10 Hz). They found scaling relations between As and Is for eruption tremors and explosion events. However, the universality of these relations is yet to be verified, and the physical meanings of As and Is are not clear. In this study, we analyzed the relations between As and Is for eruption tremors and explosion events at active volcanoes in Japan, and estimated As and Is by the ASL method. We obtained power-law relations between As and Is, in which the powers were different between eruption tremors and explosion events. These relations were consistent with the scaling relations at Tungurahua volcano. Then, we compared As with maximum eruption plume heights (H) during eruption tremors analyzed in this study, and found that H was proportional to 0.21 power of As. This relation is similar to the plume height model based on the physical process of plume rise, which indicates that H is proportional to 0.25 power of volumetric flow rate for plinian eruptions. This suggests that As may correspond to volumetric flow rate. If we assume a seismic source with volume changes and far-field S-wave, As is proportional to the source volume rate. This proportional relation and the plume height model give rise to the relation that H is proportional to 0.25 power of As. These results suggest that we may be able to estimate plume heights in realtime by estimating As during eruptions from seismic observations.

  2. Benchmarking (Code2Code) of the 1Hs 3-Bladed Onshore VAWT

    DEFF Research Database (Denmark)

    Galinos, Christos; Schmidt Paulsen, Uwe

    This study is part of the Inflow project. In this report the Nenuphar’s onshore 3-bladed Vertical Axis Wind Turbine (VAWT) prototype (1HS) is modelled in HAWC2 aeroelastic code. In the first part the model properties are summarized. Then the analysis is focused on the rotor performance and various...

  3. HS and E Application Technology branch progress report, July 1982-July 1983

    International Nuclear Information System (INIS)

    Deitesfeld, C.A.

    1984-01-01

    This report summarizes the applied research activities of the Health, Safety and Environment (HS and E) Application Technology branch at Rocky Flats Plant from July 1982 to July 1983. In this report, major headings present studies in three fields: general safety, radiation safety and environment, and health and safety engineering and meteorological studies

  4. ANALYTICAL SOLUTION FOR WAVES IN PLANETS WITH ATMOSPHERIC SUPERROTATION. I. ACOUSTIC AND INERTIA-GRAVITY WAVES

    Energy Technology Data Exchange (ETDEWEB)

    Peralta, J.; López-Valverde, M. A. [Instituto de Astrofísica de Andalucía (CSIC), Glorieta de la Astronomía, 18008 Granada (Spain); Imamura, T. [Institute of Space and Astronautical Science-Japan Aerospace Exploration Agency 3-1-1, Yoshinodai, Chuo-ku, Sagamihara, Kanagawa 252-5210 (Japan); Read, P. L. [Department of Physics, University of Oxford, Clarendon Laboratory, Parks Road, Oxford (United Kingdom); Luz, D. [Centro de Astronomia e Astrofísica da Universidade de Lisboa (CAAUL), Observatório Astronómico de Lisboa, Tapada da Ajuda, 1349-018 Lisboa (Portugal); Piccialli, A., E-mail: peralta@iaa.es [LATMOS, UVSQ, 11 bd dAlembert, 78280 Guyancourt (France)

    2014-07-01

    This paper is the first of a two-part study devoted to developing tools for a systematic classification of the wide variety of atmospheric waves expected on slowly rotating planets with atmospheric superrotation. Starting with the primitive equations for a cyclostrophic regime, we have deduced the analytical solution for the possible waves, simultaneously including the effect of the metric terms for the centrifugal force and the meridional shear of the background wind. In those cases when the conditions for the method of the multiple scales in height are met, these wave solutions are also valid when vertical shear of the background wind is present. A total of six types of waves have been found and their properties were characterized in terms of the corresponding dispersion relations and wave structures. In this first part, only waves that are direct solutions of the generic dispersion relation are studied—acoustic and inertia-gravity waves. Concerning inertia-gravity waves, we found that in the cases of short horizontal wavelengths, null background wind, or propagation in the equatorial region, only pure gravity waves are possible, while for the limit of large horizontal wavelengths and/or null static stability, the waves are inertial. The correspondence between classical atmospheric approximations and wave filtering has been examined too, and we carried out a classification of the mesoscale waves found in the clouds of Venus at different vertical levels of its atmosphere. Finally, the classification of waves in exoplanets is discussed and we provide a list of possible candidates with cyclostrophic regimes.

  5. Extended Long Wave Hindcast inside Port Solutions to Minimize Resonance

    Directory of Open Access Journals (Sweden)

    Gabriel Diaz-Hernandez

    2016-02-01

    Full Text Available The present study shows a methodology to carry out a comprehensive study of port agitation and resonance analysis in Geraldton Harbor (Western Australia. The methodology described and applied here extends the short and long wave hindcast outside the harbor and towards the main basin. To perform such an analysis, and as the first stage of the methodology, it is necessary to determine, in detail, both the long and short wave characteristics, through a comprehensive methodology to obtain and to hindcast the full spectral data (short waves + long waves, for frequencies between 0.005 and 1 Hz. Twelve-year spectral hindcast wave data, at a location before the reef, have been modified analytically to include the energy input associated with infragravity waves. A decomposition technique based on the energy balance of the radiation stress of short waves is followed. Predictions for long wave heights and periods at different harbor locations are predicted and validated with data recorded during 2004 to 2009. This new database will ensure an accurate and reliable assessment of long wave hourly data (height, period and currents in any area within the main basin of the Port of Geraldton, for its present geometry. With this information, two main task will be completed: (1 undertake a forensic diagnosis of the present response of the harbor, identifying those forcing characteristics related to inoperability events; and (2 propose any layout solutions to minimize, change, dissipate/fade/vanish or positively modify the effects of long waves in the harbor, proposing different harbor geometry modifications. The goal is to identify all possible combinations of solutions that would minimize the current inoperability in the harbor. Different pre-designs are assessed in this preliminary study in order to exemplify the potential of the methodology.

  6. Impact of Solutol HS 15 on the pharmacokinetic behavior of midazolam upon intravenous administration to male Wistar rats.

    Science.gov (United States)

    Bittner, Beate; González, Roberto Carlos Bravo; Isel, Hughes; Flament, Christophe

    2003-07-01

    The pharmacokinetic profile of midazolam (MDZ) and its major metabolites 1'-OH-midazolam (1'OH-MDZ) and 4-OH-midazolam (4OH-MDZ) was investigated in rats. MDZ was administered intravenously at 5 mg/kg either in the absence (NaCl 0.9%, control group) or in the presence of the surfactant Solutol HS 15, a weak inhibitor of cytochrome P450 3A (CYP3A) activity in vitro (Solutol HS 15-treated group). It was found that the pharmacokinetic profiles of MDZ, 1'OH-MDZ and 4OH MDZ did not differ significantly in the two dosing vehicles (P values above 0.2). MDZ exhibited a high plasma clearance (Cl) of 79 and 92 ml/min/kg (corresponding to a blood Cl of 64 and 75 ml/min/kg), a high volume of distribution (V(d)) of 4.0 and 3.6 l/kg, and an area under the plasma concentration-time curve (AUC(t0-tinf)) of 1062 and 932 h.ng/ml in the control group and in the Solutol HS 15-treated group, respectively. The amount of MDZ excreted unchanged into urine was below 0.01% with both dosing vehicles. AUC(t0-tinf) in the control group was 12.3 h.ng/ml for 1'OH-MDZ and 38.8 h.ng/ml 4OH-MDZ. In the Solutol HS 15-treated group, AUC(t0-tinf) was 14 h.ng/ml for 1'OH-MDZ and 35.4 h.ng/ml for 4OH-MDZ. The metabolite concentrations excreted into urine were below the limit of quantification. In the rat, MDZ has a high blood clearance that is limited by liver blood flow. Therefore, weak CYP3A inhibitors like Solutol HS 15 are not likely to affect the hepatic blood clearance of MDZ in vivo.

  7. Residual liquefaction of seabed under standing waves

    DEFF Research Database (Denmark)

    Kirca, V.S. Ozgur; Sumer, B. Mutlu; Fredsøe, Jørgen

    2013-01-01

    This paper presents the results of an experimental study of the seabed liquefaction beneath standing waves. Silt (with d50 =0.070mm) was used in the experiments. Two kinds of measurements were carried out: pore water pressure measurements and water surface elevation measurements. These measurements...... were synchronized with video recording of the liquefaction process from the side. The ranges of the various quantities in the experiments were wave height H= 5.9-12.0 cm, wave period T= 1.09s, and water depth h=30 cm. The experiments show that the seabed liquefaction under standing waves, although...... qualitatively similar, show features different from that caused by progressive waves. The pore water pressure builds up (or accumulated) in the areas around the node and subsequently spreads out toward the antinodes. The experimental results imply that this transport is caused by a diffusion mechanism...

  8. Experimental and Numerical Studies on Wave Breaking Characteristics over a Fringing Reef under Monochromatic Wave Conditions

    Directory of Open Access Journals (Sweden)

    Jong-In Lee

    2014-01-01

    Full Text Available Fringing reefs play an important role in protecting the coastal area by inducing wave breaking and wave energy dissipation. However, modeling of wave transformation and energy dissipation on this topography is still difficult due to the unique structure. In the present study, two-dimensional laboratory experiments were conducted to investigate the cross-shore variations of wave transformation, setup, and breaking phenomena over an idealized fringing reef with the 1/40 reef slope and to verify the Boussinesq model under monochromatic wave conditions. One-layer and two-layer model configurations of the Boussinesq model were used to figure out the model capability. Both models predicted well (r2>0.8 the cross-shore variation of the wave heights, crests, troughs, and setups when the nonlinearity is not too high (A0/h0<0.07 in this study. However, as the wave nonlinearity and steepness increase, the one-layer model showed problems in prediction and stability due to the error on the vertical profile of fluid velocity. The results in this study revealed that one-layer model is not suitable in the highly nonlinear wave condition over a fringing reef bathymetry. This data set can contribute to the numerical model verification.

  9. Modeling internal wave generation by seamounts in oceans

    Science.gov (United States)

    Zhang, L.; Buijsman, M. C.; Comino, E. L.; Swinney, H.

    2017-12-01

    Recent global bathymetric data at 30 arc-sec resolution has revealed that there are 33,452 seamounts and 138,412 knolls in the oceans. To develop an estimate for the energy converted from tidal flow to internal gravity waves, we have conducted numerical simulations using the Massachusetts Institute of Technology circulation model (MITgcm) to compute the energy conversion by randomly distributed Gaussian-shaped seamounts. We find that for an isolated axisymmetric seamount of height 1100 m and radius 1600 m, which corresponds to the Wessel height-to-radius ratio 0.69, the conversion rate is 100 kW, assuming a tidal speed amplitude 1 cm/s, buoyancy frequency 1e-3 rad/s, and circularly polarized tidal motion, and taking into account the earth's rotation. The 100 kW estimate is about 60% less than the 3-D linear theory prediction because fluid goes around a seamount instead of over it. Our estimate accounts the suppression of energy conversion due to wave interference at the generation site of closely spaced seamounts. We conclude that for randomly distributed Gaussian seamounts of varying widths and separations, separated on average by 18 km as in the oceans, wave interference reduces the energy conversion by seamounts by only about 16%. This result complements previous studies of wave interference for 2-D ridges.

  10. Stress wave velocity patterns in the longitudinal-radial plane of trees for defect diagnosis

    Science.gov (United States)

    Guanghui Li; Xiang Weng; Xiaocheng Du; Xiping Wang; Hailin Feng

    2016-01-01

    Acoustic tomography for urban tree inspection typically uses stress wave data to reconstruct tomographic images for the trunk cross section using interpolation algorithm. This traditional technique does not take into account the stress wave velocity patterns along tree height. In this study, we proposed an analytical model for the wave velocity in the longitudinal–...

  11. Preparation and pharmacokinetic evaluation of curcumin solid dispersion using Solutol® HS15 as a carrier.

    Science.gov (United States)

    Seo, Sang-Wan; Han, Hyo-Kyung; Chun, Myung-Kwan; Choi, Hoo-Kyun

    2012-03-15

    Solubility of curcumin at physiological pH was significantly increased by forming solid dispersion (SD) with Solutol® HS15. Since curcumin undergoes hydrolytic degradation, chemical stability study was conducted in pH 1.2, 6.8 and 7.4 buffer media. Solutol® HS15 exhibited superior stabilizing effect to Cremophor® RH40 and Kollidon® 30. The physical state of the dispersed curcumin in the polymer matrix was characterized by differential scanning calorimetry and X-ray diffraction studies. SD preparation transformed curcumin into amorphous form and facilitated micellar incorporation, thereby preventing hydrolysis in aqueous medium. In vitro drug release in pH 6.8 buffer revealed that SD (1:10) improved the dissolution of curcumin with approximately 90% release of the drug within 1h. Pharmacokinetic study of the solid dispersion formulation in rat showed that bioavailability of the drug was significantly improved as compared to pure curcumin. SD containing 1:10 ratio of drug and Solutol® HS15 resulted in approximately 5 fold higher AUC(0-12h). SD formulation was physically stable over the study period of 3 months. Copyright © 2011 Elsevier B.V. All rights reserved.

  12. Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene x gender interaction.

    Science.gov (United States)

    Wang, Ke-Sheng; Wang, Liang; Liu, Xuefeng; Zeng, Min

    2013-12-01

    The heparan sulfate 6-O-sulfotransferase 3 (HS6ST3) gene is involved in heparan sulphate and heparin metabolism, and has been reported to be associated with diabetic retinopathy in type 2 diabetes.We hypothesized that HS6ST3 gene polymorphisms might play an important role in obesity and related phenotypes (such as triglycerides). We examined genetic associations of 117 single-nucleotide polymorphisms (SNPs) within the HS6ST3 gene with obesity and triglycerides using two Caucasian samples: the Marshfield sample (1442 obesity cases and 2122 controls), and the Health aging and body composition (Health ABC) sample (305 cases and 1336 controls). Logistic regression analysis of obesity as a binary trait and linear regression analysis of triglycerides as a continuous trait, adjusted for age and sex, were performed using PLINK. Single marker analysis showed that six SNPs in the Marshfield sample and one SNP in the Health ABC sample were associated with obesity (P triglycerides in the Marshfield sample (P triglycerides in the Marshfield sample. These findings contribute new insights into the pathogenesis of obesity and triglycerides and demonstrate the importance of gender differences in the aetiology.

  13. Wave climate and trends along the eastern Chukchi Arctic Alaska coast

    Science.gov (United States)

    Erikson, L.H.; Storlazzi, C.D.; Jensen, R.E.

    2011-01-01

    Due in large part to the difficulty of obtaining measurements in the Arctic, little is known about the wave climate along the coast of Arctic Alaska. In this study, numerical model simulations encompassing 40 years of wave hind-casts were used to assess mean and extreme wave conditions. Results indicate that the wave climate was strongly modulated by large-scale atmospheric circulation patterns and that mean and extreme wave heights and periods exhibited increasing trends in both the sea and swell frequency bands over the time-period studied (1954-2004). Model simulations also indicate that the upward trend was not due to a decrease in the minimum icepack extent. ?? 2011 ASCE.

  14. Experimental validation of a mathematical model for seabed liquefaction in waves

    DEFF Research Database (Denmark)

    Sumer, B. Mutlu; Kirca, Özgür; Fredsøe, Jørgen

    2011-01-01

    This paper summarizes the results of an experimental study directed towards the validation of a mathematical model for the buildup of pore water pressure and resulting liquefaction of marine soils under progressive waves. Experiments were conducted under controlled conditions with silt ( d50 = 0.......070 mm) in a wave flume with a soil pit. Waves with wave heights in the range 7.7-18 cm with the water depth 55 cm and the wave period 1.6 s enabled us to study both the liquefaction and no-liquefaction regime pore water pressure buildup. The experimental data was used to validate the model. A numerical...

  15. Development and validation of the International Hidradenitis Suppurativa Severity Score System (IHS4), a novel dynamic scoring system to assess HS severity

    DEFF Research Database (Denmark)

    Zouboulis, C C; Tzellos, T; Kyrgidis, A

    2017-01-01

    BACKGROUND: A validated tool for the dynamic severity assessment of hidradenitis suppurativa/acne inversa (HS) is lacking. OBJECTIVES: To develop and validate a novel dynamic scoring system to assess the severity of HS. METHODS: A Delphi voting procedure was conducted among the members......, as well as examination for correlation (Spearman's rho) and agreement (Cohen's kappa) with existing scores, were engaged to recognize the variables for a new International HS4 (IHS4) that was established by a second Delphi round. RESULTS: Consensus HS4 was based on number of skin lesions, number of skin....... Three candidate scores were presented to the second Delphi round. The resulting IHS4 score is arrived at by the number of nodules (multiplied by 1) plus the number of abscesses (multiplied by 2) plus the number of draining tunnels (multiplied by 4). A total score of 3 or less signifies mild, 4...

  16. Transitioning high sensitivity cardiac troponin I (hs-cTnI) into routine diagnostic use: More than just a sensitivity issue

    LENUS (Irish Health Repository)

    Lee, Graham R

    2016-04-01

    High sensitivity cardiac troponin T and I (hs-cTnT and hs-cTnI) assays show analytical, diagnostic and prognostic improvement over contemporary sensitive cTn assays. However, given the importance of troponin in the diagnosis of myocardial infarction, implementing this test requires rigorous analytical and clinical verification across the total testing pathway. This was the aim of this study.

  17. The influence of alkali fatty acids on the properties and the stability of parenteral O/W emulsions modified with solutol HS 15.

    Science.gov (United States)

    Buszello, K; Harnisch, S; Müller, R H; Müller, B W

    2000-03-01

    Arachis oil based parenteral O/W emulsions were prepared using soya bean phosphatidylcholine (SPC) and different combinations of co-emulsifiers containing polyethylene glycol fatty acid esters (Solutol HS 15) and alkali fatty acids (sodium laurate, sodium stearate). The parameters measured were droplet size (both by photon correlation spectroscopy and laser diffractometry), pH and zeta potential. All emulsions were subjected to autoclaving. The addition of polyethylene glycol 12-hydroxy stearate (Solutol HS 15) led to a significant decrease of mean oil droplet size. For long-term stability the amount added turned out to be the most important factor. With increased amounts of Solutol HS 15 the packing density of the emulsifier layer and the zeta potential decreased leading to instability. The optimum load of Solutol HS 15 was found to be 15 micromol/ml. Alkali fatty acids markedly improved the physical stability of the emulsions. Improved stability properties conferred to emulsions by alkali fatty acids could be attributed to the zeta potential increase even in the presence of Solutol HS 15. Consequently a mixed emulsifier film was established in which the ionized fatty acids determined the interface charge. In addition to this a strengthening of the molecular interactions occurring between phospholipid and Solutol HS 15 emulsifier in the presence of ionized fatty acids at the O/W interface can be assumed (L. Rydhag, The importance of the phase behaviour of phospholipids for emulsion stability, Fette Seifen Anstrichm. 81 (1979) 168-173). Different co-emulsifier mixtures were shown to have a pronounced impact on the plasma protein adsorption onto emulsion droplets.

  18. Wave Height and Water Level Variability on Lakes Michigan and St Clair

    Science.gov (United States)

    2012-10-01

    Observations: http://www.ssec.wisc.edu/sose/glwx_activity.html 4. NASA Atlas of Extratropical Storm Tracks: http://data.giss.nasa.gov/stormtracks...term meteorological, ice, wave, and water level measurements. 15. SUBJECT TERMS Base flood elevation Coastal flood Extratropical storms Great...Box 1027 Detroit, MI 48231-1027 ERDC/CHL TR-12-23 ii Abstract The Great Lakes are subject to coastal flooding as a result of severe storms

  19. Effects of Deep Water Source-Sink Terms in 3rd generation Wave Model SWAN using different wind data in Black Sea

    Science.gov (United States)

    Kirezci, Cagil; Ozyurt Tarakcioglu, Gulizar

    2016-04-01

    coefficient (WAM Cycle 3).The second method follows the quassi linear wind-wave theory by Janssen(1989,1991) which also considers the atmospheric boundary layer effects and the roughness length of the sea surface (WAM Cycle 4).(SWAN Technical Documentation,2015) The dissipation caused by whitecapping depends on the steepness of the waves. There are two different steepness dependent coefficient configurations in SWAN model corresponding to the selected wind-wave interaction formulations which are mentioned above (Komen and Janssen approaches). Lastly ,there are 3 options for defining deep water non-linear wave-wave interaction, which are DIA(Discrete Interaction Approximation)by Hasselman (quadruplets), XNL(which is based on the original six-dimensional Boltzmann integral formulation of Hasselmann), and multiple DIA which considers up to 6 wave number configurations by Hashimoto et al. (2002).(SWAN Technical Documentation,2015) In this study, 540 test cases are modelled using all possible selections of deep water source and sinks approaches available in SWAN model. The computed results are compared with buoy measurements. The uncertainty due to different source sink selections are quantified using different statistical analysis. Preliminary results show that some of the term configurations predict the significant wave height (Hs) less than actual values measured at the buoy locations. One of the reasons of the underestimation of the wave parameters could be the lower wind speed estimated in closed basins and the other one is the uncertainties in the wind-sea interaction. All of the results, comparisons and discussions will highlight the best source sink approach to be used to model extreme wave events in Black Sea. References Kirezci C., Ozyurt G., (2015), "Comparison of Wave Models in Black Sea", UK YCSEC 2015, 21-23 March 2015, Manchester Özhan, E. and Abdalla, S.,(1999)"Wind and Wave Climotology of the Turkish Coast and the Black Sea:An Overview of the NATO TU-WAVES

  20. Modal Identification in an Automotive Multi-Component System Using HS 3D-DIC

    Directory of Open Access Journals (Sweden)

    Ángel Jesús Molina-Viedma

    2018-02-01

    Full Text Available The modal characterization of automotive lighting systems becomes difficult using sensors due to the light weight of the elements which compose the component as well as the intricate access to allocate them. In experimental modal analysis, high speed 3D digital image correlation (HS 3D-DIC is attracting the attention since it provides full-field contactless measurements of 3D displacements as main advantage over other techniques. Different methodologies have been published that perform modal identification, i.e., natural frequencies, damping ratios, and mode shapes using the full-field information. In this work, experimental modal analysis has been performed in a multi-component automotive lighting system using HS 3D-DIC. Base motion excitation was applied to simulate operating conditions. A recently validated methodology has been employed for modal identification using transmissibility functions, i.e., the transfer functions from base motion tests. Results make it possible to identify local and global behavior of the different elements of injected polymeric and metallic materials.

  1. Modal Identification in an Automotive Multi-Component System Using HS 3D-DIC.

    Science.gov (United States)

    Molina-Viedma, Ángel Jesús; López-Alba, Elías; Felipe-Sesé, Luis; Díaz, Francisco A

    2018-02-05

    The modal characterization of automotive lighting systems becomes difficult using sensors due to the light weight of the elements which compose the component as well as the intricate access to allocate them. In experimental modal analysis, high speed 3D digital image correlation (HS 3D-DIC) is attracting the attention since it provides full-field contactless measurements of 3D displacements as main advantage over other techniques. Different methodologies have been published that perform modal identification, i.e., natural frequencies, damping ratios, and mode shapes using the full-field information. In this work, experimental modal analysis has been performed in a multi-component automotive lighting system using HS 3D-DIC. Base motion excitation was applied to simulate operating conditions. A recently validated methodology has been employed for modal identification using transmissibility functions, i.e., the transfer functions from base motion tests. Results make it possible to identify local and global behavior of the different elements of injected polymeric and metallic materials.

  2. Modal Identification in an Automotive Multi-Component System Using HS 3D-DIC

    Science.gov (United States)

    López-Alba, Elías; Felipe-Sesé, Luis; Díaz, Francisco A.

    2018-01-01

    The modal characterization of automotive lighting systems becomes difficult using sensors due to the light weight of the elements which compose the component as well as the intricate access to allocate them. In experimental modal analysis, high speed 3D digital image correlation (HS 3D-DIC) is attracting the attention since it provides full-field contactless measurements of 3D displacements as main advantage over other techniques. Different methodologies have been published that perform modal identification, i.e., natural frequencies, damping ratios, and mode shapes using the full-field information. In this work, experimental modal analysis has been performed in a multi-component automotive lighting system using HS 3D-DIC. Base motion excitation was applied to simulate operating conditions. A recently validated methodology has been employed for modal identification using transmissibility functions, i.e., the transfer functions from base motion tests. Results make it possible to identify local and global behavior of the different elements of injected polymeric and metallic materials. PMID:29401725

  3. Unified height systems after GOCE

    Science.gov (United States)

    Rummel, Reiner; Gruber, Thomas; Sideris, Michael; Rangelova, Elena; Woodworth, Phil; Hughes, Chris; Ihde, Johannes; Liebsch, Gunter; Rülke, Axel; Gerlach, Christian; Haagmans, Roger

    2015-04-01

    The objectives of global height unification are twofold, (1) the realization of accurate geopotential numbers C together with their standard deviation σ(C) at a selected set of stations (datum points of national height systems, geodetic fundamental stations (IERS), primary tide gauges (PSMSL) and primary reference clocks (IERS)) and (2) the determination of height off-sets between all existing regional/national height systems and one global height reference. In the future the primary method of height determination will be GPS-levelling with very stringent requirements concerning the consistency of the positioning and the gravity potential difference part. Consistency is required in terms of the applied standards (ITRF, zero tide system, geodetic reference system). Geopotential differences will be based on a next generation geopotential model combining GOCE and GRACE and a best possible collection of global terrestrial and altimetric gravity and topographic data. Ultimately, the envisaged accuracy of height unification is about 10 cm2/s2 (or 1cm). At the moment, in well surveyed regions, an accuracy of about 40 to 60 cm2/s2 (or 4 to 6cm) is attainable. Objective One can be realized by straight forward computation of geopotential numbers C, i.e. geopotential differences relative to an adopted height reference. No adjustment is required for this. Objective Two, the unification of existing height systems is achieved by employing a least-squares adjustment based on the GBVP-approach. In order to attain a non-singular solution, this requires for each included datum zone at least one geo-referenced station per zone, i.e. its ellipsoidal height h and, in addition, the corresponding physical height H (geopotential number, normal height, orthometric height, etc.). Changes in geopotential numbers of consecutive realizations reflect (1) temporal changes of station heights, (2) improvements or changes of the applied geopotential (or geoid) model and (3) improvements of the

  4. Global effects of income and income inequality on adult height and sexual dimorphism in height.

    Science.gov (United States)

    Bogin, Barry; Scheffler, Christiane; Hermanussen, Michael

    2017-03-01

    Average adult height of a population is considered a biomarker of the quality of the health environment and economic conditions. The causal relationships between height and income inequality are not well understood. We analyze data from 169 countries for national average heights of men and women and national-level economic factors to test two hypotheses: (1) income inequality has a greater association with average adult height than does absolute income; and (2) neither income nor income inequality has an effect on sexual dimorphism in height. Average height data come from the NCD-RisC health risk factor collaboration. Economic indicators are derived from the World Bank data archive and include gross domestic product (GDP), Gross National Income per capita adjusted for personal purchasing power (GNI_PPP), and income equality assessed by the Gini coefficient calculated by the Wagstaff method. Hypothesis 1 is supported. Greater income equality is most predictive of average height for both sexes. GNI_PPP explains a significant, but smaller, amount of the variation. National GDP has no association with height. Hypothesis 2 is rejected. With greater average adult height there is greater sexual dimorphism. Findings support a growing literature on the pernicious effects of inequality on growth in height and, by extension, on health. Gradients in height reflect gradients in social disadvantage. Inequality should be considered a pollutant that disempowers people from the resources needed for their own healthy growth and development and for the health and good growth of their children. © 2017 Wiley Periodicals, Inc.

  5. Simulation and Optimization of Surface Acoustic Wave Devises

    DEFF Research Database (Denmark)

    Dühring, Maria Bayard

    2007-01-01

    In this paper a method to model the interaction of the mechanical field from a surface acoustic wave and the optical field in the waveguides of a Mach-Zehnder interferometer is presented. The surface acoustic waves are generated by interdigital transducers using a plane strain model...... in effective refractive index introduced in the Mach-Zehnder interferometer arms by the stresses from the surface acoustic wave is calculated. It is shown that the effective refractive index of the fundamental optical mode increases at a surface acoustic wave crest and decreases at a trough. The height...... of a piezoelectric, inhomogeneous material and reflections from the boundaries are avoided by applying perfectly matched layers. The optical modes in the waveguides are modeled by the time-harmonic wave equation for the magnetic field. The two models are coupled using the stress-optical relation and the change...

  6. Multivariate Hybrid Modelling of Future Wave-Storms at the Northwestern Black Sea

    Directory of Open Access Journals (Sweden)

    Jue Lin-Ye

    2018-02-01

    Full Text Available The characterization of future wave-storms and their relationship to large-scale climate can provide useful information for environmental or urban planning at coastal areas. A hybrid methodology (process-based and statistical was used to characterize the extreme wave-climate at the northwestern Black Sea. The Simulating WAve Nearshore spectral wave-model was employed to produce wave-climate projections, forced with wind-fields projections for two climate change scenarios: Representative Concentration Pathways (RCPs 4.5 and 8.5. A non-stationary multivariate statistical model was built, considering significant wave-height and peak-wave-period at the peak of the wave-storm, as well as storm total energy and storm-duration. The climate indices of the North Atlantic Oscillation, East Atlantic Pattern, and Scandinavian Pattern have been used as covariates to link to storminess, wave-storm threshold, and wave-storm components in the statistical model. The results show that, first, under both RCP scenarios, the mean values of significant wave-height and peak-wave-period at the peak of the wave-storm remain fairly constant over the 21st century. Second, the mean value of storm total energy is more markedly increasing in the RCP4.5 scenario than in the RCP8.5 scenario. Third, the mean value of storm-duration is increasing in the RCP4.5 scenario, as opposed to the constant trend in the RCP8.5 scenario. The variance of each wave-storm component increases when the corresponding mean value increases under both RCP scenarios. During the 21st century, the East Atlantic Pattern and changes in its pattern have a special influence on wave-storm conditions. Apart from the individual characteristics of each wave-storm component, wave-storms with both extreme energy and duration can be expected in the 21st century. The dependence between all the wave-storm components is moderate, but grows with time and, in general, the severe emission scenario of RCP8.5 presents

  7. WAVE DIRECTION and Other Data from FIXED PLATFORM From North Pacific Ocean and Others from 19810817 to 19940323 (NODC Accession 9400105)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains Wave Energy (wave height and wave period) Data from Hawaiian coast collected over 13 years in North Pacific Ocean, NE Pacific (limit-180)....

  8. Co-located wind-wave farm synergies (Operation and Maintenance): A case study

    International Nuclear Information System (INIS)

    Astariz, S.; Perez-Collazo, C.; Abanades, J.; Iglesias, G.

    2015-01-01

    Highlights: • The shielding effect of WECs located around the wind farm is analysed. • The height wave reductions achieved by 15 different layouts are compared. • The increase in the accessibility to the wind turbines is quantified. • Alpha Ventus offshore wind farm is considered as baseline scenario. • High-resolution numerical modelling (SWAN) and real sea conditions are used. - Abstract: Operation and maintenance can jeopardise the financial viability of an offshore wind energy project due to the cost of downtime, repairs and, above all, the inevitable uncertainties. The variability of wave climate can impede or hinder emergency repairs when a failure occurs, and the resulting delays imply additional costs which ultimately reduce the competitiveness of offshore wind energy as an alternative to fossil fuels. Co-located wind turbines and Wave Energy Converters (WECs) are proposed in this paper as a novel solution: the reduction of the significant wave height brought about by the WECs along the periphery of the wind farm results in a milder wave climate within the farm. This reduction, also called shadow effect, enlarges weather windows for Operation and Maintenance (O and M). The objective of this paper is to investigate the increase in the accessibility time to the turbines and to optimise the layout for the co-located wind-wave farm in order to maximise this time. The investigation is carried out through a case study: Alpha Ventus, an operating offshore wind farm. To maximise the reduction of wave height in the turbine area no fewer than 15 layouts are tested using high-resolution numerical modelling, and a sensitivity analysis is conducted. The results show that, thanks to the wave energy extraction by the WECs, weather windows (access time) can increase very significantly – over 80%. This substantial effect, together with other benefits from the combination of wave and offshore wind power in a co-located farm (common electrical infrastructures

  9. Kelvin wave coupling from TIMED and GOCE: Inter/intra-annual variability and solar activity effects

    Science.gov (United States)

    Gasperini, Federico; Forbes, Jeffrey M.; Doornbos, Eelco N.; Bruinsma, Sean L.

    2018-06-01

    The primary mechanism through which energy and momentum are transferred from the lower atmosphere to the thermosphere is through the generation and propagation of atmospheric waves. It is becoming increasingly evident that a few waves from the tropical wave spectrum preferentially propagate into the thermosphere and contribute to modify satellite drag. Two of the more prominent and well-established tropical waves are Kelvin waves: the eastward-propagating 3-day ultra-fast Kelvin wave (UFKW) and the eastward-propagating diurnal tide with zonal wave number 3 (DE3). In this work, Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) temperatures at 110 km and Gravity field and steady-state Ocean Circulation Explorer (GOCE) neutral densities and cross-track winds near 260 km are used to demonstrate vertical coupling in this height regime due to the UFKW and DE3. Significant inter- and intra-annual variability is found in DE3 and the UFKW, with evidence of latitudinal broadening and filtering of the latitude structures with height due to the effect of dissipation and mean winds. Additionally, anti-correlation between the vertical penetration of these waves to the middle thermosphere and solar activity level is established and explained through the effect of molecular dissipation.

  10. Trends in surface wind speed and significant wave height as revealed by ERA-Interim wind wave hindcast in the Central Bay of Bengal

    Digital Repository Service at National Institute of Oceanography (India)

    Shanas, P.R.; SanilKumar, V.

    height. The area average analysis is carried out to investigate the sensitivity of the identified trend results for the point location and found similar trends for extreme wind speed and SWH. The high (>5 m) annual maximum SWH in the study area...

  11. System of the Wind Wave Operational Forecast by the Black Sea Marine Forecast Center

    Directory of Open Access Journals (Sweden)

    Yu.B. Ratner

    2017-10-01

    Full Text Available System of the wind wave operational forecast in the Black Sea based on the SWAN (Simulating Waves Nearshore numerical spectral model is represented. In the course of the system development the SWAN model was adapted to take into account the features of its operation at the Black Sea Marine Forecast Center. The model input-output is agreed with the applied nomenclature and the data representation formats. The user interface for rapid access to simulation results was developed. The model adapted to wave forecast in the Black Sea in a quasi-operational mode, is validated for 2012–2015. Validation of the calculation results was carried out for all five forecasting terms based on the analysis of two-dimensional graphs of the wave height distribution derived from the data of prognostic calculations and remote measurements obtained with the altimeter installed on the Jason-2 satellite. Calculation of the statistical characteristics of the deviations between the wave height prognostic values and the data of their measurements from the Jason-2 satellite, as well as a regression analysis of the relationship between the forecasted and measured wave heights was additionally carried out. A comparison of the results obtained with the similar results reported in the works of other authors published in 2009–2016 showed their satisfactory compliance with each other. The forecasts carried out by the authors for the Black Sea as well as those obtained for the other World Ocean regions show that the current level of numerical methods for sea wave forecasting is in full compliance with the requirements of specialists engaged in studying and modeling the state of the ocean and the atmosphere, as well as the experts using these results for solving applied problems.

  12. Design Loads on Platforms on Offshore wind Turbine Foundations with Respect to Vertical Wave Run-up

    DEFF Research Database (Denmark)

    Damsgaard, Mathilde L.; Gravesen, Helge; Andersen, Thomas Lykke

    2007-01-01

    reduction in the loads by up to 75%. Furthermore it is indicated, that the fact that offshore wind turbines often are placed on limited water depths thereby increasing the amount of (nearly) breaking waves, seems to increase the run-up height and thereby the pressures on the structure.......Experiences have shown that the vertical run-up generated by waves meeting the offshore wind turbine foundations, can result in rather vigorous loads on appurtenances and platform structures. This study aims to provide a qualitative method of determining run-up height and the following loads...

  13. A comparison of osteoprotegerin with adiponectin and high-sensitivity C-reactive protein (hsCRP) as a marker for insulin resistance.

    LENUS (Irish Health Repository)

    O'Sullivan, Eoin P

    2013-01-01

    Insulin resistance (IR) is associated with low adiponectin and elevated high sensitivity C-reactive protein (hsCRP). Osteoprotegerin (OPG) has been shown to be elevated in type 2 diabetes, but whether it reflects underlying IR is unclear. We aimed to compare the ability of serum OPG with adiponectin and hsCRP to act as a marker for IR in individuals with normal and abnormal glucose tolerance.

  14. Wind-wave, and turbidity time-series data from Little Holland Tract (station HWC), Sacramento-San Joaquin Delta, California

    Data.gov (United States)

    Department of the Interior — Time series data of water surface elevation, wave height, and turbidity were collected in Little Holland Tract (LHT) beginning in December 2015 as part of “Wind-wave...

  15. Clinical significance of determination of changes of serum IGF-II, IL-6, IL-8 and hs-CRP levels after treatment in pediatric patients with bronchopneumonia

    International Nuclear Information System (INIS)

    Wang Guanghui; Chen Chuanbing; Wang Xianwu

    2009-01-01

    Objective: To explore the clinical significance of changes of serum IGF-II, IL-6, IL-8 and hs-CRP levels after treatment in pediatric patients with bronchopneumonia. Methods: Serum IGF-II, IL-6, IL-8 (with RIA) and hs-CRP (with immunoturbidity method) levels were determined in 36 pediatric patients with bronchopneumonia both before and after treatment as well as in 35 controls. Results: Before treatment, serum IGF-II, IL-6, IL-8 and hs-CRP levels in the patients were significantly higher than those in the controls (P 0.05). Conclusion: Determination of serum IGF-II, IL-6, IL-8 and hs-CRP levels in pediatric patients with bronchopneumonia was important for diagnosis and outcome prediction. (authors)

  16. Determination of Sesquiterpenes in Wines by HS-SPME Coupled with GC-MS

    OpenAIRE

    Cincotta, Fabrizio; Verzera, Antonella; Tripodi, Gianluca; Condurso, Concetta

    2015-01-01

    The sesquiterpene compounds present in red wines were characterized and quantified by Headspace Solid-Phase Microextraction in combination with Gas Chromatography–Mass Spectrometry (HS-SPME-GC-MS). Sixteen sesquiterpenes were identified, mainly hydrocarbons but also derived oxygenated compounds. Sesquiterpenes were acyclic, monocyclic, byciclic and tryciclic. Sesquiterpenes were detected in SIM (selected ion monitoring) mode using their characteristics ions. All the sesquiterpenes were identi...

  17. Lipid nanocapsules containing the non-ionic surfactant Solutol HS15 inhibit the transport of calcium through hyperforin-activated channels in neuronal cells.

    Science.gov (United States)

    Chauvet, Sylvain; Barras, Alexandre; Boukherroub, Rabah; Bouron, Alexandre

    2015-12-01

    Hyperforin is described as a natural antidepressant inhibiting the reuptake of neurotransmitters and also activating cation channels. However the blood-brain barrier limits the access to the brain of this biomolecule. To circumvent this problem it was envisaged to encapsulate hyperforin into biomimetic lipid nano-carriers like lipid nanocapsules (LNCs). When testing the safety of 25 nm LNCs it appeared that they strongly blocked hyperforin-activated Ca2+ channels of cultured cortical neurons. This inhibition was due to one of their main component: solutol HS15 (polyoxyethylene-660-12-hydroxy stearate), a non-ionic soluble surfactant. Solutol HS15 rapidly depresses in a concentration-dependent manner the entry of Ca2+ through hyperforin-activated channels without influencing store-operated channels. This effect is mimicked by Brij58 but not by PEG600, indicating that the lipid chain of Solutol HS15 is important in determining its effects on the channels. The inhibition of the Ca2+ fluxes depends on the cellular cholesterol content; it is stronger after depleting cholesterol with methyl-β-cyclodextrin and is nearly absent on cells cultured in a cholesterol-rich medium. When chronically applied for 24 h, Solutol HS15 slightly up-regulates the entry of Ca2+ through hyperforin-activated channels. Similar observations were made when testing 25 nm lipid nanocapsules containing the surfactant Solutol HS15. Altogether, this study shows that Solutol HS15 perturbs in a cholesterol-dependent manner the activity of some neuronal channels. This is the first demonstration that LNCs containing this surfactant can influence cellular calcium signaling in the brain, a finding that can have important clinical implications. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. An artificial generation of a few specific wave conditions: New simulator design and experimental performance

    International Nuclear Information System (INIS)

    Ramadan, A.; Mohamed, M.H.; Marzok, S.Y.; Montasser, O.A.; El Feky, A.; El Baz, A.R.

    2014-01-01

    In recent years, an amplified global awareness has led to a reawakening of interest in renewable energy technology. In an effort to reduce the worldwide dependence on fossil fuels, cleaner power generation methods are being sought in the field of solar, biomass, wind and wave energy. The importance of wave energy is increased in particular in some countries like UK, Portugal, Spain and Japan. A considerable progress has already been achieved in this field but the available technical designs are not adequate to develop reliable wave energy converters. Wave energy is the most available energy associated in water seas and oceans. Simultaneously, the wave energy has consisted of two types of energies: potential and kinetic energy. Therefore, many attempts have been applied to capture these energies. In the present work, a wave generator device has been designed and manufactured to simulate and generate the heaving motion of sea waves with different specification. A PC based electro-pneumatic control system was designed and implemented to individually control wave height, these heights are 3, 8, 16, 18 and 20 cm and different frequencies to generate these regular and irregular waves. - Highlights: • Wave energy is one of the most promising sources of renewable energy. • Most researchers built huge flume to simulate waves with large size and high budget. • A new simulator design for the direct and indirect wave energy is introduced. • The regular and irregular wave can be obtained for the new wave simulator. • This design is compact, flexible in terms amplitude, frequencies and high accuracy

  19. Changes to extreme wave climates of islands within the Western Tropical Pacific throughout the 21st century under RCP 4.5 and RCP 8.5, with implications for island vulnerability and sustainability

    Science.gov (United States)

    Shope, James B.; Storlazzi, Curt; Erikson, Li; Hegermiller, Christie

    2016-01-01

    Waves are the dominant influence on coastal morphology and ecosystem structure of tropical Pacific islands. Wave heights, periods, and directions for the 21st century were projected using near-surface wind fields from four atmosphere-ocean coupled global climate models (GCM) under representative concentration pathways (RCP) 4.5 and 8.5. GCM-derived wind fields forced the global WAVEWATCH-III wave model to generate hourly time-series of bulk wave parameters around 25 islands in the mid to western tropical Pacific Ocean for historical (1976–2005), mid-, and end-of-century time periods. Extreme significant wave heights decreased (~10.0%) throughout the 21st century under both climate scenarios compared to historical wave conditions and the higher radiative forcing 8.5 scenario displayed a greater and more widespread decrease in extreme significant wave heights compared to the lower forcing 4.5 scenario. An exception was for the end-of-century June–August season. Offshore of islands in the central equatorial Pacific, extreme significant wave heights displayed the largest changes from historical values. The frequency of extreme events during December–February decreased under RCP 8.5, whereas the frequency increased under RCP 4.5. Mean wave directions often rotated more than 30° clockwise at several locations during June–August, which could indicate a weakening of the trade winds’ influence on extreme wave directions and increasing dominance of Southern Ocean swell or eastern shift of storm tracks. The projected changes in extreme wave heights, directions of extreme events, and frequencies at which extreme events occur will likely result in changes to the morphology and sustainability of island nations.

  20. An overview of the numerical and neural network accosts of ocean wave prediction

    Digital Repository Service at National Institute of Oceanography (India)

    Mandal, S.; Prabaharan, N.

    .8 1.2 1.6 Avg. Measured wave height (m) 0.0 0.4 0.8 1.2 1.6 Fo re ca ste d a vg . w av e h eig ht (m ) COPEDEC VI, 2003, Colombo, Sri Lanka 8 5. CONCLUSIONS The use of neural network for wave prediction will have future application...

  1. Clinical significance of determination of changes of serum hs-CRP, TNF-α and E2 levels in female children with simple obesity

    International Nuclear Information System (INIS)

    Xue Jie; Xu Weiqin; Zhou Hong; Liu Hongshu

    2008-01-01

    Objective: To explore the clinical significance of changes of serum hs-CRP, TNF-α and E 2 levels in female children with simple obesity. Methods: Serum levels of TNF-α, E 2 (with RIA) and hs-CRP (with immunity turbidity) were detected in 34 female children with simple obesity and 35 controls. Results: In the children with simple obesity, the serum hs-CRP, TNF- α and E 2 levels were significantly higher than those in controls (P 2 levels were mutually positively correlated (r=0.6182, 0.5784, P 2 levels is of help for assessment of severity of obesity as well as outcome prediction in female children. (authors)

  2. Wave and offshore wind potential for the island of Tenerife

    International Nuclear Information System (INIS)

    Veigas, M.; Iglesias, G.

    2013-01-01

    Highlights: • The island aims to reduce its carbon footprint by developing renewable energy. • The substantial wave and offshore wind resources around the island are examined. • One area is appropriate for installing a hybrid wave–offshore wind farm. - Abstract: The island of Tenerife, a UNESCO Biosphere Reserve in the Atlantic Ocean, aims to be energy self-sufficient in order to reduce its carbon footprint. To accomplish this goal it should develop the renewable sources, in particular wave and offshore wind energy. The objectives of this work are twofold; (i) to characterize the wave and offshore wind power distribution around the island and (ii) to determine which offshore area is best suited for their exploitation, taking into account the resource and other conditioning factors such as the bathymetry, distance to the coastline and ports, and offshore zoning. To carry out this research, hindcast wave and wind data obtained with numerical models are used alongside observations from meteorological stations. One area, in the vicinity of Puerto de la Cruz, is identified as having great potential for installing a hybrid floating wave–wind farm. Both resources are characterized for the area selected: the wave resource in terms of wave directions, significant wave heights and energy periods; the offshore wind resource in terms of directions and speeds in addition to the seasonality for the both resources. It is found that most of the wave resource is provided by N and NNW waves with significant wave heights between 1.5 m and 3.0 m and energy periods between 10 s and 14 s. It follows that the Wave Energy Converters deployed in the area should have maximum efficiency in those ranges. As for the offshore wind resource, most of the energy corresponds to NNE and NE winds with speeds between 9 and 14 m s −1 , which should be taken into account when selecting the offshore wind turbines

  3. Occupational Accident Declaration Form (HS50)

    CERN Multimedia

    HR Department

    2007-01-01

    https://cern.ch/service-procedures/AdminMan/Forms/HS50E.doc •\tIt must be completed within 10 working days of the date on which the accident occurred (§ 29.2.1), unless the person concerned is materially unable to meet this deadline. • The completed formula must be accompanied by a medical certificate giving details of any bodily injuries resulting from the accident (Annex 1, § 5). The medical certificate must be obtained from the doctor who has been consulted for that purpose. Benefits resulting from illnesses and accidents Medical treatment will cease to be reimbursed under the occupational scheme in the event of cure (defined in § 15 as the certified end to the impairment of the patient’s state of health caused by the illness or accident), or consolidation (defined in § 14 as certification that no further improvement in the patient’s state of health can be expected from appropriate medical treatment). The right to such reimbursement shall resume only in the...

  4. Prediction of regular wave loads on a fixed offshore oscillating water column-wave energy converter using CFD

    Directory of Open Access Journals (Sweden)

    Ahmed Elhanafi

    2016-12-01

    Full Text Available In this paper, hydrodynamic wave loads on an offshore stationary–floating oscillating water column (OWC are investigated via a 2D and 3D computational fluid dynamics (CFD modeling based on the RANS equations and the VOF surface capturing scheme. The CFD model is validated against previous experiments for nonlinear regular wave interactions with a surface-piercing stationary barge. Following the validation stage, the numerical model is modified to consider the pneumatic damping effect, and an extensive campaign of numerical tests is carried out to study the wave–OWC interactions for different wave periods, wave heights and pneumatic damping factors. It is found that the horizontal wave force is usually larger than the vertical one. Also, there a direct relationship between the pneumatic and hydrodynamic vertical forces with a maximum vertical force almost at the device natural frequency, whereas the pneumatic damping has a little effect on the horizontal force. Additionally, simulating the turbine damping with an orifice plate induces higher vertical loads than utilizing a slot opening. Furthermore, 3D modeling significantly escalates and declines the predicted hydrodynamic vertical and horizontal wave loads, respectively.

  5. Simulation of Irregular Waves and Wave Induced Loads on Wind Power Plants in Shallow Water

    Energy Technology Data Exchange (ETDEWEB)

    Trumars, Jenny [Chalmers Univ. of Technology, Goeteborg (Sweden). Dept. of Water Environment Transport

    2004-05-01

    The essay gives a short introduction to waves and discusses the problem with non-linear waves in shallow water and how they effect an offshore wind energy converter. The focus is on the realisation of non-linear waves in the time domain from short-term statistics in the form of a variance density spectrum of the wave elevation. For this purpose the wave transformation from deep water to the near to shore site of a wind energy farm at Bockstigen has been calculated with the use of SWAN (Simulating Waves Near Shore). The result is a wave spectrum, which can be used as input to the realisation. The realisation of waves is done by perturbation theory to the first and second-order. The properties calculated are the wave elevation, water particle velocity and acceleration. The wave heights from the second order perturbation equations are higher than those from the first order perturbation equations. This is also the case for the water particle kinematics. The increase of variance is significant between the first order and the second order realisation. The calculated wave elevation exhibits non-linear features as the peaks become sharper and the troughs flatter. The resulting forces are calculated using Morison's equation. For second order force and base moment there is an increase in the maximum values. The force and base moment are largest approximately at the zero up and down crossing of the wave elevation. This indicates an inertia dominated wave load. So far the flexibility and the response of the structure have not been taken into account. They are, however, of vital importance. For verification of the wave model the results will later on be compared with measurements at Bockstigen off the coast of Gotland in the Baltic Sea.

  6. Proinsulin, adiponectin and hsCRP in reproductive age women with polycystic ovary syndrome (PCOS)--the effect of metformin treatment.

    Science.gov (United States)

    Kruszyńska, Aleksandra; Słowińska-Srzednicka, Jadwiga; Jeske, Wojciech; Zgliczyński, Wojciech

    2014-01-01

    Women with polycystic ovary syndrome (PCOS) often suffer from obesity and insulin resistance. The role of proinsulin, which is known to be an indicator of fertility outcomes in PCOS women, and that of adiponectin, in the pathogenesis of PCOS is not well elucidated. Our objective was to determine proinsulin, adiponectin, hsCRP and other hormonal and metabolic parameters in PCOS women before and after metformin treatment. Two PCOS groups of patients of reproductive age (90 lean and 88 obese or overweight) with two control groups, adjusted for body mass index (BMI), were compared at baseline. 32 PCOS women were studied at baseline, after three and six months of metformin (1,000 mg/day) treatment. Clinical, anthropometric, biochemical and hormonal parameters were assessed. Proinsulin and hsCRP levels were the highest in obese PCOS women and were statistically different than in lean PCOS women (proinsulin: 11.4 v. 6.9 pmol/L; hsCRP 2.46 v. 0.47 mg/L, p treatment only in obese PCOS women. PCOS, when accompanied by obesity, is associated with elevated proinsulin concentrations, which correlates with higher hsCRP and increased FAI. Proinsulin level decreases due to metformin treatment. Our results suggest that obese or overweight PCOS and lean PCOS are characterised by different hormonal and metabolic parameters and have a different response to metformin treatment.

  7. Nonlinear interaction and wave breaking with a submerged porous structure

    Science.gov (United States)

    Hsieh, Chih-Min; Sau, Amalendu; Hwang, Robert R.; Yang, W. C.

    2016-12-01

    Numerical simulations are performed to investigate interactive velocity, streamline, turbulent kinetic energy, and vorticity perturbations in the near-field of a submerged offshore porous triangular structure, as Stokes waves of different heights pass through. The wave-structure interaction and free-surface breaking for the investigated flow situations are established based on solutions of 2D Reynolds Averaged Navier-Stokes equations in a Cartesian grid in combination with K-ɛ turbulent closure and the volume of fluid methodology. The accuracy and stability of the adopted model are ascertained by extensive comparisons of computed data with the existing experimental and theoretical findings and through efficient predictions of the internal physical kinetics. Simulations unfold "clockwise" and "anticlockwise" rotation of fluid below the trough and the crest of the viscous waves, and the penetrated wave energy creates systematic flow perturbation in the porous body. The interfacial growths of the turbulent kinetic energy and the vorticity appear phenomenal, around the apex of the immersed structure, and enhanced significantly following wave breaking. Different values of porosity parameter and two non-porous cases have been examined in combination with varied incident wave height to reveal/analyze the nonlinear flow behavior in regard to local spectral amplification and phase-plane signatures. The evolution of leading harmonics of the undulating free-surface and the vertical velocity exhibits dominating roles of the first and the second modes in inducing the nonlinearity in the post-breaking near-field that penetrates well below the surface layer. The study further suggests the existence of a critical porosity that can substantially enhance the wave-shoaling and interface breaking.

  8. Annual Properties of Transverse Waves in the Corona over most of Solar Cycle 24

    Science.gov (United States)

    Weberg, M. J.; Morton, R. J.; McLaughlin, J. A.

    2017-12-01

    Waves are an omnipresent feature in heliophysical plasmas. In particular, transverse (or "Alfvénic") waves have been observed at a wide range of spatial and temporal scales within the corona and solar wind. These waves play a key role in transporting energy through the solar atmosphere and are also thought to contribute to the heating and acceleration of the solar wind. Previous studies of low-frequency (automated detection and measurement of low-frequency transverse waves with over 7 years of SDO / AIA data to provide a detailed picture of coronal transverse waves in polar plumes and, for the first time, begin to examine their long-term behaviour. We measure waves at three different heights in each of eight, four-hour periods spanning May 2010 - May 2017. We find that the bulk wave parameters within these 24 regions are largely consistent over most of a solar cycle. However, there is some evidence for smaller-scale variations both with height and over time periods of a few years. We also discuss total energy flux estimations based on the full wave power spectra, which yields a more nuanced picture than previous values based on summary statistics. Overall, this work expands our view of wave processes in the corona and is relevant to both theoretical and modelling considerations of energy transport within the solar atmosphere. Crucially, these initial results suggest that the energy flux provided by the low-frequency transverse waves varies little over the solar cycle, potentially indicating that the waves provide a consistent source of energy to the corona and beyond.

  9. Transfer and dissipation of energy during wave group propagation on a gentle beach slope

    Science.gov (United States)

    Padilla, Enrique M.; Alsina, José M.

    2017-08-01

    The propagation of bichromatic wave groups over a constant 1:100 beach slope and the influence of the group modulation is presented. The modulation is controlled by varying the group frequency, fg, which is shown to remarkably affect the energy transfer to high and low frequency components. The growth of the high frequency (hf) wave skewness increases when fg decreases. This is explained by nonlinear coupling between the primary frequencies, which results in a larger growth of hf components as fg decreases, causing the hf waves to break earlier. Due to high spatial resolution, wave tracking has provided an accurate measurement of the varying breakpoint. These breaking locations are very well described (R2>0.91) by the wave-height to effective-depth ratio (γ). However, for any given Iribarren number, this γ is shown to increase with fg. Therefore, a modified Iribarren number is proposed to include the grouping structure, leading to a considerable improvement in reproducing the measured γ-values. Within the surf zone, the behavior of the Incident Long Wave also depends on the group modulation. For low fg conditions, the lf wave decays only slightly by transferring energy back to the hf wave components. However, for high fg wave conditions, strong dissipation of low frequency (lf) components occurs close to the shoreline associated with lf wave breaking. This mechanism is explained by the growth of the lf wave height, induced partly by the self-self interaction of fg, and partly by the nonlinear coupling between the primary frequencies and fg.

  10. Preliminary Analysis of a Submerged Wave Energy Device

    Science.gov (United States)

    Wagner, J. R.; Wagner, J. J.; Hayatdavoodi, M.; Ertekin, R. C.

    2016-02-01

    Preliminary analysis of a submerged wave energy harvesting device is presented. The device is composed of a thin, horizontally submerged plate that is restricted to heave oscillations under the influence of surface waves. The submerged plate is oscillating, and it can be attached to a fixed rotor, or a piston, to harvest the wave energy. A fully submerged wave energy converter is preferred over a surface energy convertor due to its durability and less visual and physical distractions it presents. In this study, the device is subject to nonlinear shallow-water waves. Wave loads on the submerged oscillating plate are obtained via the Level I Green-Naghdi equations. The unsteady motion of the plate is obtained by solving the nonlinear equations of motion. The results are obtained for a range of waves with varying heights and periods. The amplitude and period of plate oscillations are analyzed as functions of the wave parameters and plate width. Particular attention is given to the selection of the site of desired wave field. Initial estimation on the amount of energy extraction from the device, located near shore at a given site, is provided.

  11. Investigating the Effect of Inflammation on Atrial Fibrillation Occurrence by Measuring Highly Sensitive C-reactive Protein (hs-CRP

    Directory of Open Access Journals (Sweden)

    Mahdi Hassanzadeh Delui

    2014-05-01

    Full Text Available Introduction: Atrial fibrillation (AF is the most prevalent cardiac arrhythmias that cardiologists and internists encounter. The goal of this article is to clarify an overview of the evidence linking inflammation to AF existence, which may highlight the effect of some pharmacological agents that have genuine potential to reduce the clinical burden of AF by modulating inflammatory pathways. Materials and Methods: In a case-control study, 50 patients with atrial fibrillation (AF with different etiologies and 50 patients with sinus rhythm and similar bases were selected. Sampling for highly sensitive c-reactive (hs-CRP was done on the patients presenting with AF to the Ghaem hospital between October 2006 and June 2007. Results: Mean age of the patients was 62 years with maximum of 90 and minimum of 36 and standard deviation of 13.80. The most frequent age group was 71-80years. Fifty-four percent of patients were male and 46% were female. Mean serum hs-CRP levels in AF patients with hypertension (HTN ,Ischemic heart disease(IHD, Valvular heart disease (VHD, HTN+IHD and hyperthyroidism were 8.10, 9.40, 8.68, 10.16 and 5.98 mg/Lit; respectively. There was significant difference between hs-CRP levels in hypertensive patients in the two groups (P=0.010. Similar results were observed in IHD patients, VHD patients and HTN+IHD patients in two groups (P=0.015, P=0.037, P=0.000. Conclusion: In addition to some risk factors like baseline cardiac diseases, aging, thyrotoxicosis, pulmonary embolism, pneumonia and cardiac surgery, there also appears to be consistent links between hs-CRP, a marker of inflammation, and the pathogenesis of AF. Introduction: Atrial fibrillation (AF is the most prevalent cardiac arrhythmias that cardiologists and internists encounter. The goal of this article is to clarify an overview of the evidence linking inflammation to AF existence, which may highlight the effect of some pharmacological agents that have genuine potential to

  12. Efficiency Analysis of a Wave Power Generation System by Using Multibody Dynamics

    International Nuclear Information System (INIS)

    Kim, Min Soo; Sohn, Jeong Hyun; Kim, Jung Hee; Sung, Yong Jun

    2016-01-01

    The energy absorption efficiency of a wave power generation system is calculated as the ratio of the wave power to the power of the system. Because absorption efficiency depends on the dynamic behavior of the wave power generation system, a dynamic analysis of the wave power generation system is required to estimate the energy absorption efficiency of the system. In this study, a dynamic analysis of the wave power generation system under wave loads is performed to estimate the energy absorption efficiency. RecurDyn is employed to carry out the dynamic analysis of the system, and the Morison equation is used for the wave load model. According to the results, the lower the wave height and the shorter the period, the higher is the absorption efficiency of the system

  13. Efficiency Analysis of a Wave Power Generation System by Using Multibody Dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Min Soo; Sohn, Jeong Hyun [Pukyong National Univ., Busan (Korea, Republic of); Kim, Jung Hee; Sung, Yong Jun [INGINE Inc., Seoul (Korea, Republic of)

    2016-06-15

    The energy absorption efficiency of a wave power generation system is calculated as the ratio of the wave power to the power of the system. Because absorption efficiency depends on the dynamic behavior of the wave power generation system, a dynamic analysis of the wave power generation system is required to estimate the energy absorption efficiency of the system. In this study, a dynamic analysis of the wave power generation system under wave loads is performed to estimate the energy absorption efficiency. RecurDyn is employed to carry out the dynamic analysis of the system, and the Morison equation is used for the wave load model. According to the results, the lower the wave height and the shorter the period, the higher is the absorption efficiency of the system.

  14. Comparison of different statistical methods for estimation of extreme sea levels with wave set-up contribution

    Science.gov (United States)

    Kergadallan, Xavier; Bernardara, Pietro; Benoit, Michel; Andreewsky, Marc; Weiss, Jérôme

    2013-04-01

    Estimating the probability of occurrence of extreme sea levels is a central issue for the protection of the coast. Return periods of sea level with wave set-up contribution are estimated here in one site : Cherbourg in France in the English Channel. The methodology follows two steps : the first one is computation of joint probability of simultaneous wave height and still sea level, the second one is interpretation of that joint probabilities to assess a sea level for a given return period. Two different approaches were evaluated to compute joint probability of simultaneous wave height and still sea level : the first one is multivariate extreme values distributions of logistic type in which all components of the variables become large simultaneously, the second one is conditional approach for multivariate extreme values in which only one component of the variables have to be large. Two different methods were applied to estimate sea level with wave set-up contribution for a given return period : Monte-Carlo simulation in which estimation is more accurate but needs higher calculation time and classical ocean engineering design contours of type inverse-FORM in which the method is simpler and allows more complex estimation of wave setup part (wave propagation to the coast for example). We compare results from the two different approaches with the two different methods. To be able to use both Monte-Carlo simulation and design contours methods, wave setup is estimated with an simple empirical formula. We show advantages of the conditional approach compared to the multivariate extreme values approach when extreme sea-level occurs when either surge or wave height is large. We discuss the validity of the ocean engineering design contours method which is an alternative when computation of sea levels is too complex to use Monte-Carlo simulation method.

  15. Test particle modeling of wave-induced energetic electron precipitation

    International Nuclear Information System (INIS)

    Chang, H.C.; Inan, U.S.

    1985-01-01

    A test particle computer model of the precipitation of radiation belt electrons is extended to compute the dynamic energy spectrum of transient electron fluxes induced by short-duration VLF wave packets traveling along the geomagnetic field lines. The model is adapted to estimate the count rate and associated spectrum of precipitated electrons that would be observed by satellite-based particle detectors with given geometric factor and orientation with respect to the magnetic field. A constant-frequency wave pulse and a lightning-induced whistler wave packet are used as examples of the stimulating wave signals. The effects of asymmetry of particle mirror heights in the two hemispheres and the atmospheric backscatter of loss cone particles on the computed precipitated fluxes are discussed

  16. 77 FR 19033 - Effect of Adding References to HS 6104.32 To Correct the U.S.-Korea FTA Product-Specific Rules of...

    Science.gov (United States)

    2012-03-29

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. Korea FTA-103-026] Effect of Adding References to HS 6104.32 To Correct the U.S.- Korea FTA Product-Specific Rules of Origin AGENCY: United States... investigation No. Korea FTA-103-026, Effect of Adding References to HS 6104.32 To Correct the U.S.-Korea FTA...

  17. Clinical significance of determination of changes in serum hs-CRP, IL-6, IL-10, and IL-18 levels after treatment in patients with acute conjunctivitis

    International Nuclear Information System (INIS)

    Liu Jun

    2007-01-01

    Objective: To study the clinical significance of changes of serum hs-CRP, IL-6, IL-10 and IL-18 levels in patients with acute conjunctivitis after treatment. Methods: Serum IL-6, IL-10 (with RIA) hs-CRP (with Immuno-turbidity) and IL-18 (with ELISA) levels were measured in 38 patients with acute conjunctivitis both before and after treatment as well as in 35 controls. Results: The serum hs-CRP, IL-6, IL-10 and IL-18 levels in the patients before treatment were significantly higher than those in the controls (P 0.05). Conclusion: Measurement of the changes of serum hs-CRP, IL-6, IL-10 and IL-18 levels after treatment might be inportant for outcome prediction in patients with acute conjunctivitis. (authors)

  18. Wave optics simulation of statistically rough surface scatter

    Science.gov (United States)

    Lanari, Ann M.; Butler, Samuel D.; Marciniak, Michael; Spencer, Mark F.

    2017-09-01

    The bidirectional reflectance distribution function (BRDF) describes optical scatter from surfaces by relating the incident irradiance to the exiting radiance over the entire hemisphere. Laboratory verification of BRDF models and experimentally populated BRDF databases are hampered by sparsity of monochromatic sources and ability to statistically control the surface features. Numerical methods are able to control surface features, have wavelength agility, and via Fourier methods of wave propagation, may be used to fill the knowledge gap. Monte-Carlo techniques, adapted from turbulence simulations, generate Gaussian distributed and correlated surfaces with an area of 1 cm2 , RMS surface height of 2.5 μm, and correlation length of 100 μm. The surface is centered inside a Kirchhoff absorbing boundary with an area of 16 cm2 to prevent wrap around aliasing in the far field. These surfaces are uniformly illuminated at normal incidence with a unit amplitude plane-wave varying in wavelength from 3 μm to 5 μm. The resultant scatter is propagated to a detector in the far field utilizing multi-step Fresnel Convolution and observed at angles from -2 μrad to 2 μrad. The far field scatter is compared to both a physical wave optics BRDF model (Modified Beckmann Kirchhoff) and two microfacet BRDF Models (Priest, and Cook-Torrance). Modified Beckmann Kirchhoff, which accounts for diffraction, is consistent with simulated scatter for multiple wavelengths for RMS surface heights greater than λ/2. The microfacet models, which assume geometric optics, are less consistent across wavelengths. Both model types over predict far field scatter width for RMS surface heights less than λ/2.

  19. SugE belongs to the small multidrug resistance (SMR) protein family involved in tributyltin (TBT) biodegradation and bioremediation by alkaliphilic Stenotrophomonas chelatiphaga HS2.

    Science.gov (United States)

    Hassan, Hamdy A

    2018-03-01

    Tributyltin (TBT) used in a variety of industrial processes, subsequent discharge into the environment, its fate, toxicity and human exposure are topics of current concern. TBT degradation by alkaliphilic bacteria may be a key factor in the remediation of TBT in high pH contaminated sites. In this study, Stenotrophomonas chelatiphaga HS2 were isolated and identified from TBT contaminated site in Mediterranean Sea. S. chelatiphaga HS2 has vigor capability to transform TBT into dibutyltin and monobutyltin (DBT and MBT) at pH 9 and 7% NaCl (w/v). A gene was amplified and characterized from strain HS2 as SugE protein belongs to SMR protein family, a reverse transcription polymerase chain reaction analysis confirmed that SugE protein involved in the TBT degradation by HS2 strain. TBT bioremediation was investigated in stimulated TBT contaminated sediment samples (pH 9) using S chelatiphaga HS2 in association with E. coli BL21 (DE3)-pET28a(+)-sugE instead of S chelatiphaga HS2 alone reduced significantly the TBT half-life from 12d to 5d, although no TBT degradation appeared using E. coli BL21 (DE3)-pET28a(+)-sugE alone. This finding indicated that SugE gene increased the rate and degraded amount of TBT and is necessary in enhancing TBT bioremediation. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. A novel imidazopyridine derivative, HS-106, induces apoptosis of breast cancer cells and represses angiogenesis by targeting the PI3K/mTOR pathway.

    Science.gov (United States)

    Li, Guang-Yong; Jung, Kyung Hee; Lee, Hyunseung; Son, Mi Kwon; Seo, JuHyeon; Hong, Sang-Won; Jeong, Yujeong; Hong, Sungwoo; Hong, Soon-Sun

    2013-02-01

    Abnormal activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway is an essential step for the formation and growth of tumors in humans. HS-106 is an imidazopyridine derivative that inhibits the kinase activity of PI3K by binding to the ATP-binding cleft. We found that this compound suppressed breast cancer cell proliferation and induced apoptosis by specifically inhibiting the activity of target proteins in the PI3K/Akt/mTOR signaling pathway. Cell cycle analysis revealed that treatment with HS-106 resulted in cell cycle arrest at the G(2)/M phase due to up-regulation of p-cdc25 and down-regulation of cyclin B1. Also, HS-106 induced apoptosis by increasing the levels of cleaved caspase-3 and cleaved PARP. In addition, chromatin condensation and apoptotic bodies were detected in HS-106-treated breast cancer cells. Furthermore, HS-106 decreased the expression of hypoxia-inducible factor 1α (HIF-1α), and inhibited tube formation and migration of human umbilical vein endothelial cells (HUVECs) in vitro and blood vessel formation in an in vivo Matrigel plug assay. These results show that HS-106 may be an effective novel therapeutic candidate in clinical trials as a potential treatment for human breast cancers or other advanced malignancies with aberrant PI3K/Akt/mTOR signaling. Crown Copyright © 2012. Published by Elsevier Ireland Ltd. All rights reserved.

  1. The effect of novel surfactants and Solutol HS 15 on paclitaxel aqueous solubility and permeability across a Caco-2 monolayer.

    Science.gov (United States)

    Alani, Adam W G; Rao, Deepa A; Seidel, Ron; Wang, Jian; Jiao, Jim; Kwon, Glen S

    2010-08-01

    The effect of novel surfactants on the aqueous solubility and the permeability of paclitaxel across a Caco-2 cell monolayer were examined in this work. The solubility and permeability of paclitaxel was evaluated in the presence of four soft surfactants (SS) KXN441, KXN424, KXN437, and KXN 337 and Solutol HS15. All surfactants increased the aqueous solubility of paclitaxel. Caco-2 cell membrane integrity in the presence of SS and Solutol HS15 was assessed by mannitol permeability and LDH release. All surfactants were tested at 0.5x CMC, 5x CMC and 1.5 mM concentrations. The effect of SSs on paclitaxel permeability was concentration dependent. At all concentrations tested, KXN 441 and Solutol HS 15 showed partially inhibition of drug efflux with no discernable change in mannitol permeability or cytotoxicity as observed with LDH release. At these concentrations, other SSs exhibited some partial efflux inhibition along with compromised membrane integrity and increasing mannitol permeability. In conclusion, all SSs were able to increase the aqueous solubility and permeability of paclitaxel across Caco-2 cells monolayer. However, KXN441 and Solutol HS15 were able to enhance paclitaxel permeability across Caco-2 monolayer without cytotoxicity. (c) 2010 Wiley-Liss, Inc. and the American Pharmacists Association

  2. Physiological pattern of lumbar disc height

    International Nuclear Information System (INIS)

    Biggemann, M.; Frobin, W.; Brinckmann, P.

    1997-01-01

    Purpose of this study is to present a new method of quantifying objectively the height of all discs in lateral radiographs of the lumbar spine and of analysing the normal craniocaudal sequence pattern of lumbar disc heights. Methods: The new parameter is the ventrally measured disc height corrected for the dependence on the angle of lordosis by normalisation to mean angles observed in the erect posture of healthy persons. To eliminate radiographic magnification, the corrected ventral height is related to the mean depth of the cranially adjoining vertebra. In this manner lumbar disc heights were objectively measured in young, mature and healthy persons (146 males and 65 females). The craniocaudal sequence pattern was analysed by mean values from all persons and by height differences of adjoining discs in each individual lumbar spine. Results: Mean normative values demonstrated an increase in disc height between L1/L2 and L4/L5 and a constant or decreasing disc height between L4/L5 and L5/S1. However, this 'physiological sequence of disc height in the statistical mean' was observed in only 36% of normal males and 55% of normal females. Conclusion: The radiological pattern of the 'physiological sequence of lumbar disc height' leads to a relevant portion of false positive pathological results especially at L4/L5. An increase of disc height from L4/L5 to L5/S1 may be normal. The recognition of decreased disc height should be based on an abrupt change in the heights of adjoining discs and not on a deviation from a craniocaudal sequence pattern. (orig.) [de

  3. Essential oil from Rhaponticum acaule L. roots: Comparative study using HS-SPME/GC/GC–MS and hydrodistillation techniques

    Directory of Open Access Journals (Sweden)

    Batoul Benyelles

    2014-12-01

    Full Text Available The composition of essential oil extracted from Rhaponticum acaule L. roots growing wild in Algeria was studied by hydrodistillation (HD and by Head-Space Solid Phase Micro-Extraction (HS-SPME. Quantitative but not qualitative differences have been found in the chemical composition of both analysed samples depending on the extraction method. However, the oil obtained from R. acaule roots shows that aliphatic alcohols were found to be the major class (69.2%, followed by the terpenes (5.5%, alkenes (5.2% and alkynes (4.0%. In both cases the analysis were carried out using Gas Chromatography (GC and Gas Chromatography–Mass Spectrometry (GC–MS. Our study shows that HS-SPME extraction could be considered as an alternative technique for the isolation of volatiles from plant. 25 components were identified in oil vs. 39 in the HS-SPME. However the oil composition of roots was mainly represented by a variety of aliphatic hydrocarbons (alcohols, aldehydes and ketones and terpenes which are known for their antimicrobial activities.

  4. Adult height, nutrition, and population health

    Science.gov (United States)

    Perkins, Jessica M.; Subramanian, S.V.; Davey Smith, George

    2016-01-01

    In this review, the potential causes and consequences of adult height, a measure of cumulative net nutrition, in modern populations are summarized. The mechanisms linking adult height and health are examined, with a focus on the role of potential confounders. Evidence across studies indicates that short adult height (reflecting growth retardation) in low- and middle-income countries is driven by environmental conditions, especially net nutrition during early years. Some of the associations of height with health and social outcomes potentially reflect the association between these environmental factors and such outcomes. These conditions are manifested in the substantial differences in adult height that exist between and within countries and over time. This review suggests that adult height is a useful marker of variation in cumulative net nutrition, biological deprivation, and standard of living between and within populations and should be routinely measured. Linkages between adult height and health, within and across generations, suggest that adult height may be a potential tool for monitoring health conditions and that programs focused on offspring outcomes may consider maternal height as a potentially important influence. PMID:26928678

  5. In defense of the classical height system

    Science.gov (United States)

    Foroughi, Ismael; Vaníček, Petr; Sheng, Michael; Kingdon, Robert William; Santos, Marcelo C.

    2017-11-01

    In many European countries, normal heights referred to the quasi-geoid as introduced by Molodenskij in the mid-20th century are preferred to the classical height system that consists of orthometric heights and the geoid as a reference surface for these heights. The rationale for this choice is supposed to be that in the classical height system, neither the geoid, nor the orthometric height can be ever known with centimetre level accuracy because one would need to know the topographical mass density to a level that can never be achieved. The aim of this paper is to question the validity of this rationale. The common way of assessing the congruency of a local geoid model and the orthometric heights is to compare the geoid heights with the difference between orthometric heights provided by leveling and geodetic heights provided by GNSS. On the other hand, testing the congruency of a quasi-geoidal model with normal height a similar procedure is used, except that instead of orthometric heights, normal heights are employed. For the area of Auvergne, France, which is now a more or less standard choice for precise geoid or quasi-geoid testing, only the normal heights are supplied by the Institute Geographic National, the provider of the data. This is clearly the consequence of the European preference for the Molodenskij system. The quality of the height system is to be judged by the congruency of the difference of the geoid/quasi-geoid heights subtracted from the geodetic heights and orthometric/normal heights. To assess the congruency of the classical height system, the Helmert approximation of orthometric heights is typically used as the transformation between normal and Helmert's heights is easily done. However, the evaluation of the differences between Helmert's and the rigorous orthometric heights is somewhat more involved as will be seen from the review in this paper. For the area of interest, the differences between normal and Helmert's heights at the control

  6. Impacts of wave-induced circulation in the surf zone on wave setup

    Science.gov (United States)

    Guérin, Thomas; Bertin, Xavier; Coulombier, Thibault; de Bakker, Anouk

    2018-03-01

    Wave setup corresponds to the increase in mean water level along the coast associated with the breaking of short-waves and is of key importance for coastal dynamics, as it contributes to storm surges and the generation of undertows. Although overall well explained by the divergence of the momentum flux associated with short waves in the surf zone, several studies reported substantial underestimations along the coastline. This paper investigates the impacts of the wave-induced circulation that takes place in the surf zone on wave setup, based on the analysis of 3D modelling results. A 3D phase-averaged modelling system using a vortex force formalism is applied to hindcast an unpublished field experiment, carried out at a dissipative beach under moderate to very energetic wave conditions (Hm 0 = 6m at breaking and Tp = 22s). When using an adaptive wave breaking parameterisation based on the beach slope, model predictions for water levels, short waves and undertows improved by about 30%, with errors reducing to 0.10 m, 0.10 m and 0.09 m/s, respectively. The analysis of model results suggests a very limited impact of the vertical circulation on wave setup at this dissipative beach. When extending this analysis to idealized simulations for different beach slopes ranging from 0.01 to 0.05, it shows that the contribution of the vertical circulation (horizontal and vertical advection and vertical viscosity terms) becomes more and more relevant as the beach slope increases. In contrast, for a given beach slope, the wave height at the breaking point has a limited impact on the relative contribution of the vertical circulation on the wave setup. For a slope of 0.05, the contribution of the terms associated with the vertical circulation accounts for up to 17% (i.e. a 20% increase) of the total setup at the shoreline, which provides a new explanation for the underestimations reported in previously published studies.

  7. Lower energy radial shock wave therapy improves characteristics of hypertrophic scar in a rabbit ear model.

    Science.gov (United States)

    Zhao, Jing-Chun; Zhang, Bo-Ru; Shi, Kai; Wang, Jian; Yu, Qing-Hua; Yu, Jia-Ao

    2018-01-01

    The aim of the present study was to investigate the effects of radial extracorporeal shock wave therapy (rESWT) on scar characteristics and transforming growth factor (TGF)-β1/Smad signaling in order to explore a potential modality for the treatment of hypertrophic scars (HS). The HS model was generated in rabbit ears, then rabbits were randomly divided into 3 groups: Lower (L)-ESWT [treated with rESWT with lower energy flux density (EFD) of 0.1 mJ/mm 2 ], higher (H)-ESWT (treated with a higher EFD of 0.18 mJ/mm 2 ) and the sham ESWT group (S-ESWT; no ESWT treatment). Scar characteristics (wrinkles, texture, diameter, area, volume of elevation, hemoglobin and melanin) were assessed using the Antera 3D ® system. The protein and mRNA expression of TGF-β1, Smad2, Smad3 and Smad7 was assessed by enzyme-linked immunosorbent assay and reverse transcription-quantitative polymerase chain reaction, respectively. The Antera 3D ® results indicated that wrinkles and hemoglobin of the HS were significantly improved in both of the rESWT groups when compared with the S-ESWT group. However, these changes appeared much earlier in the L-ESWT group than the H-ESWT. Scar texture was also improved in the L-ESWT group. However, rESWT did not influence HS diameter, area, volume of elevation or melanin levels. rESWT had no effect on TGF-β1 or Smad7 expression in either of rESWT groups. Although no difference was observed in Smad2 mRNA expression in the L-ESWT group, the Smad3 mRNA and protein expression significantly decreased when compared with the H-ESWT and S-ESWT groups. By contrast, Smad2 and Smad3 mRNA expression were upregulated in the H-ESWT group. These results demonstrated that rESWT with 0.1 mJ/mm 2 EFD improved some characteristics of the HS tissue. Downregulation of Smad3 expression may underlie this inhibitory effect. Inhibition of the TGF-β1/Smad signal transduction pathway may be a potential therapeutic target for the management of HS.

  8. Assessing the performance of wave breaking parameterizations in shallow waters in spectral wave models

    Science.gov (United States)

    Lin, Shangfei; Sheng, Jinyu

    2017-12-01

    Depth-induced wave breaking is the primary dissipation mechanism for ocean surface waves in shallow waters. Different parametrizations were developed for parameterizing depth-induced wave breaking process in ocean surface wave models. The performance of six commonly-used parameterizations in simulating significant wave heights (SWHs) is assessed in this study. The main differences between these six parameterizations are representations of the breaker index and the fraction of breaking waves. Laboratory and field observations consisting of 882 cases from 14 sources of published observational data are used in the assessment. We demonstrate that the six parameterizations have reasonable performance in parameterizing depth-induced wave breaking in shallow waters, but with their own limitations and drawbacks. The widely-used parameterization suggested by Battjes and Janssen (1978, BJ78) has a drawback of underpredicting the SWHs in the locally-generated wave conditions and overpredicting in the remotely-generated wave conditions over flat bottoms. The drawback of BJ78 was addressed by a parameterization suggested by Salmon et al. (2015, SA15). But SA15 had relatively larger errors in SWHs over sloping bottoms than BJ78. We follow SA15 and propose a new parameterization with a dependence of the breaker index on the normalized water depth in deep waters similar to SA15. In shallow waters, the breaker index of the new parameterization has a nonlinear dependence on the local bottom slope rather than the linear dependence used in SA15. Overall, this new parameterization has the best performance with an average scatter index of ∼8.2% in comparison with the three best performing existing parameterizations with the average scatter index between 9.2% and 13.6%.

  9. Asymptotic expansions for solitary gravity-capillary waves in two and three dimensions

    International Nuclear Information System (INIS)

    Ablowitz, M J; Haut, T S

    2010-01-01

    High-order asymptotic series are obtained for gravity-capillary solitary waves, where the first term in the series is the well-known sech 2 solution of the KdV equation. The asymptotic series is used, with nine terms included, to investigate the effects of surface tension on the height and energy of large amplitude waves, and waves close to the solitary version of Stokes' extreme wave. In particular, for surface tension below a critical value, the solitary wave with the maximum energy is obtained. For large surface tension, the series is also used to study the energy related to the solitary waves of depression. Energy considerations suggest that, for large enough surface tension, there are solitary waves that can get close to the fluid bottom. Comparisons are also made with recent experiments.

  10. Traveling waves of the regularized short pulse equation

    International Nuclear Information System (INIS)

    Shen, Y; Horikis, T P; Kevrekidis, P G; Frantzeskakis, D J

    2014-01-01

    The properties of the so-called regularized short pulse equation (RSPE) are explored with a particular focus on the traveling wave solutions of this model. We theoretically analyze and numerically evolve two sets of such solutions. First, using a fixed point iteration scheme, we numerically integrate the equation to find solitary waves. It is found that these solutions are well approximated by a finite sum of hyperbolic secants powers. The dependence of the soliton's parameters (height, width, etc) to the parameters of the equation is also investigated. Second, by developing a multiple scale reduction of the RSPE to the nonlinear Schrödinger equation, we are able to construct (both standing and traveling) envelope wave breather type solutions of the former, based on the solitary wave structures of the latter. Both the regular and the breathing traveling wave solutions identified are found to be robust and should thus be amenable to observations in the form of few optical cycle pulses. (paper)

  11. Sand waves on an epicontinental shelf: Northern Bering Sea

    Science.gov (United States)

    Field, M.E.; Nelson, C.H.; Cacchione, D.A.; Drake, D.E.

    1981-01-01

    Sand waves and current ripples occupy the crests and flanks of a series of large linear sand ridges (20 km ?? 5 km ?? 10 m high) lying in an open-marine setting in the northern Bering Sea. The sand wave area, which lies west of Seward Peninsula and southeast of Bering Strait, is exposed to the strong continuous flow of coastal water northward toward Bering Strait. A hierarchy of three sizes of superimposed bedforms, all facing northward, was observed in successive cruises in 1976 and 1977. Large sand waves (height 2 m; spacing 200 m) have smaller sand waves (height 1 m; spacing 20 m) lying at a small oblique angle on their stoss slopes. The smaller sand waves in turn have linguoid ripples on their stoss slopes. Repeated studies of the sand wave fields were made both years with high-resolution seismic-reflection profiles, side-scan sonographs, underwater photographs, current-meter stations, vibracores, and suspended-sediment samplers. Comparison of seismic and side-scan data collected along profile lines run both years showed changes in sand wave shape that indicate significant bedload transport within the year. Gouge marks made in sediment by keels of floating ice also showed significantly different patterns each year, further documenting modification to the bottom by sediment transport. During calm sea conditions in 1977, underwater video and camera observations showed formation and active migration of linguoid and straight-crested current ripples. Current speeds 1 m above the bottom were between 20 and 30 cm/s. Maximum current velocities and sand wave migration apparently occur when strong southwesterly winds enhance the steady northerly flow of coastal water. Many cross-stratified sand bodies in the geologic record are interpreted as having formed in a tidal- or storm-dominated setting. This study provides an example of formation and migration of large bedforms by the interaction of storms with strong uniform coastal currents in an open-marine setting. ?? 1981.

  12. An experimental study of irregular wave forces on multiple quasi-ellipse caissons

    Science.gov (United States)

    Ren, Xiaozhong; Zhang, Peng; Ma, Yuxiang; Meng, Yufan

    2014-09-01

    An experimental investigation of irregular wave forces on quasi-ellipse caisson structures is presented. Irregular waves were generated based on the Jonswap spectrum with two significant wave heights, and the spectrum peak periods range from 1.19 s to 1.81 s. Incident wave directions relative to the centre line of the multiple caissons are from 0° to 22.5°. The spacing between caissons ranges from 2 to 3 times that of the width of the caisson. The effects of these parameters on the wave forces of both the perforated and non-perforated caissons were compared and analyzed. It was found that the perforated caisson can reduce wave forces, especially in the transverse direction. Furthermore, the relative interval and incident wave direction have significant effects on the wave forces in the case of multiple caissons.

  13. The wave vane - A device to measure the breaker angle

    Digital Repository Service at National Institute of Oceanography (India)

    Chandramohan, P.; Nayak, B.U.; Anand, N.M.

    directional wave gauge at a considerable cost. For economic and practical considerations, visual measurements on the breaker height, the breaker period and the breaker angle are generally made in the LEO pro- gramme. The breaker height is recorded... of the fins. Flag masts are fixed on either end of the arms. The whole assembly thus revolves around the spindle resting on the sleeve. WORKING PRINCIPLE The flag masts, two on the revolving arms and one on the top of the spindle lie always in a straight...

  14. Optimization of HS-SPME/GC-MS analysis and its use in the profiling of illicit ecstasy tablets (Part 1).

    Science.gov (United States)

    Bonadio, Federica; Margot, Pierre; Delémont, Olivier; Esseiva, Pierre

    2009-05-30

    A headspace solid-phase microextraction procedure (HS-SPME) was developed for the profiling of traces present in 3,4-methylenedioxymethylampethamine (MDMA). Traces were first extracted using HS-SPME and then analyzed by gas chromatography-mass spectroscopy (GC-MS). The HS-SPME conditions were optimized using varying conditions. Optimal results were obtained when 40 mg of crushed MDMA sample was heated at 80 degrees C for 15 min, followed by extraction at 80 degrees C for 15 min with a polydimethylsiloxane/divinylbenzene coated fibre. A total of 31 compounds were identified as traces related to MDMA synthesis, namely precursors, intermediates or by-products. In addition some fatty acids used as tabletting materials and caffeine used as adulterant, were also detected. The use of a restricted set of 10 target compounds was also proposed for developing a screening tool for clustering samples having close profile. 114 seizures were analyzed using an SPME auto-sampler (MultiPurpose Samples MPS2), purchased from Gerstel GMBH & Co. (Germany), and coupled to GC-MS. The data was handled using various pre-treatment methods, followed by the study of similarities between sample pairs based on the Pearson correlation. The results show that HS-SPME, coupled with the suitable statistical method is a powerful tool for distinguishing specimens coming from the same seizure and specimens coming from different seizures. This information can be used by law enforcement personnel to visualize the ecstasy distribution network as well as the clandestine tablet manufacturing.

  15. Theses\\' subjects chosen from public needs: Experience of Yazd Health Study (YaHS

    Directory of Open Access Journals (Sweden)

    AA Dehghanitaftiti

    2014-12-01

    Full Text Available Yazd Health Study (YaHS is an endeavor to involve students in design, implementation and analysis of a large study. Over 150 graduate and post graduate students from various disciplines have been invited to participate in a large longitudinal study with 10000 samples. Participants were selected randomly from Yazd population, over 1000000 as December 2014. Four hundred variables grouped in the following sections were asked 1 demographics, 2 physical activity, 3sleep quality and quantity, 4 mental health, 5 history y of chronic illnesses, 6 history of surgical operations, 7 dental health, 8 history of accidents, 9 dietetic habits, 10 occupation and communication history, 11 traditional medicine, 12 history of smoking and addiction and 13 women’s health. The interview follows by anthropometric measurements including weight, height, BMI, waist circumference, hip circumference, neck circumference and WHR. Per cent body fat, % body muscle, visceral fat, resting metabolism have been measured followed by pulse and blood pressure. Students were trained to participate in design, piloting and the main phase of data collection. Students evaluated the experience useful and constructive. In return of their collaboration in interviewing 50-100 study participants, they will receive data for their theses' proposal. This will help them to access a large and high quality set of data and disseminate the results in high quality peer reviewed journals as well as national and international conferences. The students mandated to write an executive summary of their thesis and disseminate it to health managers and inter-sectoral decision makers. They will gain bonus score if they can publish their main findings in public media. Acknowledgments: Thanks to students who participated in the study and A. Professor Masoud Mirzaei, the principal investigator of Yazd Health Study (YAHS for providing information on the design and the progress of the study.

  16. Wave direction and other data from fixed platform from TOGA Area - Pacific (30 N to 30 S) from 19931027 to 19950531 (NODC Accession 9500087)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This accession contains two Wave Energy (wave height and wave period) Data files from Hawaiian coast (Kahului and Mauai islands) collected in TOGA Area - Pacific (30...

  17. Improved selectivity and cytotoxic effects of irinotecan via liposomal delivery: A comparative study on Hs68 and HeLa cells.

    Science.gov (United States)

    Casadó, Ana; Mora, Margarita; Sagristá, Maria Lluïsa; Rello-Varona, Santi; Acedo, Pilar; Stockert, Juan Carlos; Cañete, Magdalena; Villanueva, Angeles

    2017-11-15

    Irinotecan (CPT-11) is an effective chemotherapeutic agent widely used to treat different cancers. Otherwise, the liposomal delivery of anti-tumor agents has been shown to be a promising strategy. The aim of this study has been to analyze the effect of liposomal CPT-11 (CPT-11lip) on two human cell lines (Hs68 and HeLa) to establish the suitability of this CPT-11 nanocarrier. We have demonstrated the highest uptake of CPT-11lip in comparison with that of CPT-11sol, in lactate buffer, and that CPT-11lip was internalized in the cells through an endocytic process whereas CPT-11sol does so by passive diffusion. CPT-11lip was not cytotoxic to normal fibroblast Hs68 cells, but induced a massive apoptosis accompanied by cell senescence in HeLa cells. CPT-11lip treatment modified the morphology of HeLa cells, induced different cell cycle alterations and accumulated into lysosomes in both cell lines. In particular, CPT-11lip treatment showed that surviving HeLa cells remained in a state of senescence whereas only a temporal growth arrest was induced in Hs68 cells. Results of RT-PCR indicated that the different responses in Hs68 (survival) and HeLa cells (apoptotic death), seemed to be induced by a p53- and p53- independent mechanism, respectively. An analysis of DNA damage also determined that released CPT-11 from liposomes was able to reach the nucleus and exert a genotoxic effect in both cell lines, which was repaired in Hs68 but not in HeLa cells. All results indicate that phospholipid-cholesterol liposomes possess optimum properties for CPT-11 delivery, being biocompatible and selectively cytotoxic against HeLa tumorigenic cells. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  18. Wave propagation in a non-isothermal atmosphere and the solar five-minute oscillations. [Acoustic waves

    Energy Technology Data Exchange (ETDEWEB)

    Chiuderi, C; Giovanardi, C [Florence Univ. (Italy). Istituto di Astronomia

    1979-11-01

    This paper presents a detailed discussion of the properties of linear, periodic acoustic waves that propagate vertically in a non-isothermal atmosphere. In order to retain the basic feature of the solar atmosphere we have chosen a temperature profile presenting a minimum. An analytical solution of the problem is possible if T/..mu.., ..mu.. being the mean molecular weight, varies parabolically with height. The purpose of this study is to point out the qualitative differences existing between the case treated here and the customary analysis based on a locally isothermal treatment. The computed velocity amplitude and the temperature-perturbation as functions of the wave period exhibit a sharp peak in the region between 180 and 300 s, thus showing the possibility of interpreting the five-minute oscillations as a resonant phenomenon. The propagating or stationary nature of the waves is investigated by a study of the phase of the proposed analytical solution.

  19. Numerical and experimental results on the spectral wave transfer in finite depth

    Science.gov (United States)

    Benassai, Guido

    2016-04-01

    Determination of the form of the one-dimensional surface gravity wave spectrum in water of finite depth is important for many scientific and engineering applications. Spectral parameters of deep water and intermediate depth waves serve as input data for the design of all coastal structures and for the description of many coastal processes. Moreover, the wave spectra are given as an input for the response and seakeeping calculations of high speed vessels in extreme sea conditions and for reliable calculations of the amount of energy to be extracted by wave energy converters (WEC). Available data on finite depth spectral form is generally extrapolated from parametric forms applicable in deep water (e.g., JONSWAP) [Hasselmann et al., 1973; Mitsuyasu et al., 1980; Kahma, 1981; Donelan et al., 1992; Zakharov, 2005). The present paper gives a contribution in this field through the validation of the offshore energy spectra transfer from given spectral forms through the measurement of inshore wave heights and spectra. The wave spectra on deep water were recorded offshore Ponza by the Wave Measurement Network (Piscopia et al.,2002). The field regressions between the spectral parameters, fp and the nondimensional energy with the fetch length were evaluated for fetch-limited sea conditions. These regressions gave the values of the spectral parameters for the site of interest. The offshore wave spectra were transfered from the measurement station offshore Ponza to a site located offshore the Gulf of Salerno. The offshore local wave spectra so obtained were transfered on the coastline with the TMA model (Bouws et al., 1985). Finally the numerical results, in terms of significant wave heights, were compared with the wave data recorded by a meteo-oceanographic station owned by Naples Hydrographic Office on the coastline of Salerno in 9m depth. Some considerations about the wave energy to be potentially extracted by Wave Energy Converters were done and the results were discussed.

  20. Dark and composite rogue waves in the coupled Hirota equations

    International Nuclear Information System (INIS)

    Chen, Shihua

    2014-01-01

    The intriguing dark and composite rogue wave dynamics in a coupled Hirota system are unveiled, based on the exact explicit rational solutions obtained under the assumption of equal background height. It is found that a dark rogue wave state would occur as a result of the strong coupling between two field components with large wavenumber difference, and there would appear plenty of composite structures that are attributed to the specific wavenumber difference and the free choice of three independent structural parameters. The coexistence of different fundamental rogue waves in such a coupled system is also demonstrated. - Highlights: • Exact rational rogue wave solutions under different parameter conditions are presented for the coupled Hirota equations. • The basic rogue wave features and hence the intriguing dark structures are unveiled. • We attributed the diversity of composite rogue wave dynamics to the free choice of three independent structural parameters. • The remarkable coexisting rogue wave behaviors in such a coupled system are demonstrated