Clinical pathways for inborn errors of metabolism: warranted and feasible

Directory of Open Access Journals (Sweden)

Demirdas Serwet

2013-02-01

Full Text Available Abstract Inborn errors of metabolism (IEMs are known for their low prevalence and multidisciplinary care mostly founded on expert opinion. Clinical pathways are multidisciplinary tools to organise care which provide a clear route to the best care and improve communication. In 2010 the Dutch Society for Children and Adults with an Inborn Error of Metabolism (VKS initiated development of clinical pathways for inborn errors of metabolism. In this letter to the editor we describe why it is warranted to develop clinical pathways for IEMs and shortly discuss the process of development for these pathways in the Netherlands.

Warrant Officer Examinations. PR-4018

Science.gov (United States)

1944-10-10

ccouunting, Administrative - Clcorica1, Judge, Advo Ge~nc. De~ptsAdxiiniistrati~ve 1 icl Adi isrtv - Supp:ly, generaile8 ~ Administrativo ’ - Supply, Air...chronological index if action in processing special and summary records of trial. Answers teleph.’nic inquirie’s pertaining to subject matter contain- ed...reproduction by lithopraphy, black and white process printing, and gelatin duplication; moy couidinnte and supervise procurement, storage, and distribution of

Show me the goods: The warranting effect of user-generated photographs in online auctions

NARCIS (Netherlands)

Johnson, B.K.; Vang, M.H.; van der Heide, B.

2015-01-01

Consumers using online auction websites face the challenge of appraising products at a distance. Sellers and buyers in online auctions navigate this challenge by displaying and evaluating various cues, a critical one being use of photographs. Warranting theory predicts that cues less subject to

Diagnosing true virtue? Remote scenarios, warranted virtue attributions, and virtuous medical practice.

Science.gov (United States)

Oakley, Justin

2016-02-01

Immanuel Kant argues in the Foundations that remote scenarios are diagnostic of genuine virtue. When agents commonly thought to have a particular virtue fail to exhibit that virtue in an extreme situation, he argues, they do not truly have the virtue at all, and our propensities to fail in such ways indicate that true virtue might never have existed. Kant's suggestion that failure to show, say, courage in extraordinary circumstances necessarily silences one's claim to have genuine courage seems to rely on an implausibly demanding standard for warranted virtue attributions. In contrast to this approach, some philosophers-such as Robert Adams and John Doris-have argued for probabilistic accounts of warranted virtue attributions. But despite the initial plausibility of such accounts, I argue that a sole reliance on probabilistic approaches is inadequate, as they are insufficiently sensitive to considerations of credit and fault, which emerge when agents have developed various insurance strategies and protective capacities against their responding poorly to particular eventualities. I also argue that medical graduates should develop the sorts of virtuous dispositions necessary to protect patient welfare against various countervailing influences (even where such influences might be encountered only rarely), and that repeated failures to uphold the proper goals of medicine in emergency scenarios might indeed be diagnostic of whether an individual practitioner does have the relevant medical virtue. In closing, I consider the dispositions involved in friendship. I seek to develop a principled way of determining when remote scenarios can be illuminating of genuine friendship and genuine virtue.

20 CFR 416.934 - Impairments which may warrant a finding of presumptive disability or presumptive blindness.

Science.gov (United States)

2010-04-01

... Blindness Presumptive Disability and Blindness § 416.934 Impairments which may warrant a finding of presumptive disability or presumptive blindness. We may make findings of presumptive disability and... school, because of mental deficiency or is unable to attend any type of school (or if beyond school age...

Announcement effects of convertible bond loans versus warrant-bond loans : An empirical analysis for the Dutch market

NARCIS (Netherlands)

de Roon, F.A.; Veld, C.H.

1995-01-01

This study investigates the announcement effects of offerings of convertible bond loans and warrant-bond loans using data for the Dutch market. Using standard event study methodology it is found that on average stock prices show a positive but insignificant abnormal return for the announcement of a

Financial oil derivatives: from options to oil warrants and synthetic oilfields

International Nuclear Information System (INIS)

Trabia, Xavier

1992-01-01

This study aims to shed light on some of the most interesting financial oil derivatives issued so far in order to assess the potential of this new wave of innovative funding instruments. In Part I some theoretical background is provided and applied to the problem of the American futures option. The ''binomial'' model for valuing future option contracts is presented and the most accurate alternatives for pricing American futures options are reviewed. The role of these numerical procedures in valuing more complex options involved in oil warrants is examined. Comments are made on the behaviour of volatility, which stands as a key interface between theory and practice in oil trading on the oil futures market. Part II of the study describes in detail some of the most famous new financial oil derivatives. Some final conclusions are drawn on the potential of oil trusts and synthetic oilfields to be involved in project and general funding in the oil industry. (44 figures, 11 tables, 53 references) (UK)

Unreliable patient identification warrants ABO typing at admission to check existing records before transfusion.

Science.gov (United States)

Ferrera-Tourenc, V; Lassale, B; Chiaroni, J; Dettori, I

2015-06-01

This study describes patient identification errors leading to transfusional near-misses in blood issued by the Alps Mediterranean French Blood Establishment (EFSAM) to Marseille Public Hospitals (APHM) over an 18-month period. The EFSAM consolidates 14 blood banks in southeast France. It supplies 149 hospitals and maintains a centralized database on ABO types used at all area hospitals. As an added precaution against incompatible transfusion, the APHM requires ABO testing at each admission regardless of whether the patient has an ABO record. The study goal was to determine if admission testing was warranted. Discrepancies between ABO type determined by admission testing and records in the centralized database were investigated. The root cause for each discrepancy was classified as specimen collection or patient admission error. Causes of patient admission events were further subclassified as namesake (name similarity) or impersonation (identity fraud). The incidence of ABO discrepancies was 1:2334 including a 1:3329 incidence of patient admission events. Impersonation was the main cause of identity events accounting for 90.3% of cases. The APHM's ABO control policy prevented 19 incompatible transfusions. In relation to the 48,593 packed red cell units transfused, this would have corresponded to a risk of 1:2526. Collecting and storing ABO typing results in a centralized database is an essential public health tool. It allows crosschecking of current test results with past records and avoids redundant testing. However, as patient identification remains unreliable, ABO typing at each admission is still warranted to prevent transfusion errors. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Placing the pieces: Reconstructing the original property mosaic in a warrant and patent watershed

Science.gov (United States)

Bain, D.J.; Brush, G.S.

2005-01-01

Recent research shows that land use history is an important determinant of current ecosystem function. In the United States, characterization of land use change following European settlement requires reconstruction of the original property mosaic. However, this task is difficult in unsystematically surveyed areas east of the Appalachian Mountains. The Gwynns Falls watershed (Baltimore, MD) was originally surveyed in the 1600-1700s under a system of warrants and patents (commonly known as 'metes and bounds'). A method for the reconstruction and mapping of warrant and patent properties is presented and used to map the original property mosaic in the Gwynns Falls watershed. Using the mapped mosaic, the persistence of properties and property lines in the current Gwynns Falls landscape is considered. The results of this research indicate that as in agricultural areas, the original property lines in the Gwynns Falls watershed are persistent. At the same time, the results suggest that the property mosaic in heavily urbanized/suburbanized areas is generally 'reset.' Further, trends in surveying technique, parcel size, and settlement patterns cause property line density and property shape complexity to increase in the less urbanized upper watershed. The persistence of original patterns may be damping expression of heterogeneity gradients in this urban landscape. This spatial pattern of complexity in the original mosaic is directly opposite of hypothesized patterns of landscape heterogeneity arising from urbanization. The technique reported here and the resulting observations are important for landscape pattern studies in areas settled under unsystematic survey systems, especially the heavily urbanized areas of the eastern United States. ?? 2004 Kluwer Academic Publishers.

Who Becomes a Limited Duty Officer and Chief Warrant Officer? An Examination of Differences of Limited Duty Officers and Chief Warrant Officers

National Research Council Canada - National Science Library

Manuel, Walter F

2006-01-01

.... Descriptive statistics, correlation analysis was developed for year groups 1990 through 2005 to analyze the differences in background characteristics and military characteristics of both programs...

Carotid sinus hypersensitivity: Entity warrants a caution in the critical care unit

Directory of Open Access Journals (Sweden)

Sugata Dasgupta

2016-01-01

Full Text Available Carotid sinus hypersensitivity (CSH syndrome is an entity caused by an overreaction of the carotid sinus baroreceptors to stimulation. Three subtypes of CSH syndrome are recognized according to the response to carotid sinus massage (CSM: Predominantly cardioinhibitory, predominantly vasodepressor and a mixed subtype. We report here the case of a middle-aged female patient admitted in our critical care unit with respiratory failure requiring mechanical ventilation. There were episodes of severe bradycardia whenever her head was rotated to any side, relieved on neutralizing head position and administering intravenous atropine. CSM revealed she had predominantly cardioinhibitory type of CSH syndrome. A cardioinhibitory form of hypersensitive carotid sinus reflex, which is idiopathic in causation, probably explains the severe bradycardia on head rotation seen in our patient. A heightened awareness of this syndrome is necessary for timely diagnosis and management. CSH syndrome results from an overreaction of the carotid sinus baroreceptors to stimulation, manifesting commonly as bradycardia, hypotension and syncope. It is an entity, which warrants caution during routine critical care practices.

SMARTPHONE-BASED DILATED FUNDUS PHOTOGRAPHY AND NEAR VISUAL ACUITY TESTING AS INEXPENSIVE SCREENING TOOLS TO DETECT REFERRAL WARRANTED DIABETIC EYE DISEASE.

Science.gov (United States)

Toy, Brian C; Myung, David J; He, Lingmin; Pan, Carolyn K; Chang, Robert T; Polkinhorne, Alison; Merrell, Douglas; Foster, Doug; Blumenkranz, Mark S

2016-05-01

To compare clinical assessment of diabetic eye disease by standard dilated examination with data gathered using a smartphone-based store-and-forward teleophthalmology platform. 100 eyes of 50 adult patients with diabetes from a health care safety-net ophthalmology clinic. All patients underwent comprehensive ophthalmic examination. Concurrently, a smartphone was used to estimate near visual acuity and capture anterior and dilated posterior segment photographs, which underwent masked, standardized review. Quantitative comparison of clinic and smartphone-based data using descriptive, kappa, Bland-Altman, and receiver operating characteristic analyses was performed. Smartphone visual acuity was successfully measured in all eyes. Anterior and posterior segment photography was of sufficient quality to grade in 96 and 98 eyes, respectively. There was good correlation between clinical Snellen and smartphone visual acuity measurements (rho = 0.91). Smartphone-acquired fundus photographs demonstrated 91% sensitivity and 99% specificity to detect moderate nonproliferative and worse diabetic retinopathy, with good agreement between clinic and photograph grades (kappa = 0.91 ± 0.1, P smartphone-based telemedicine system that demonstrated sensitivity and specificity to detect referral-warranted diabetic eye disease as a proof-of-concept. Additional studies are warranted to evaluate this approach to expanding screening for diabetic retinopathy.

Benefits of an Air Force Contracting Warrant Officer Program

Science.gov (United States)

2011-12-01

M., & Berry, J. W. (2011). The necessity of others is the mother of invention: instrinsic and prosocial motivations , perspective taking, and...Capital, Organizational Behavioral Assessment, Implementation Plan, Air Force 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT Unclassified...10 3. Motivation

Varant Yatırımcısının Volatilite Algısına Etki Eden Faktörler: BIST’de Ampirik Bir Uygulama(Factors Affecting the Volatility Perception of Warrant Investors: An Empirical Research on BIST

Directory of Open Access Journals (Sweden)

İsrafil ZOR

2013-12-01

Full Text Available The aim of the study is to determine the factors that affect the volatility perception of warrant investors. By using 3.187 daily data of 61 call warrants whose underlying asset is BIST-30 Index and traded on BIST in 2012, firstly efficient option pricing model for the related market is confirmed and then volatilities that equalizes the efficient model prices to market prices are calculated and regression analysis is applied to determine factors that affect the volatility. The results of the analysis are revealed that if the closing price of the underlying asset, the days to maturity of the warrant and Turkish Lira Interbank rate increase, the volatility perceived by investors will decrease. Also, there is positive relationship between the closing price of warrants and the perceived volatility. In addition perceived volatility is higher on Monday and first decrease in inflation after 4 months increase reduces the perceived volatility.

46 CFR 4.03-55 - Law enforcement officer.

Science.gov (United States)

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Law enforcement officer. 4.03-55 Section 4.03-55 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC MARINE CASUALTIES AND INVESTIGATIONS Definitions § 4.03-55 Law enforcement officer. Law enforcement officer means a Coast Guard commissioned, warrant or petty officer...

Discrete-Time Pricing and Optimal Exercise of American Perpetual Warrants in the Geometric Random Walk Model

International Nuclear Information System (INIS)

Vanderbei, Robert J.; Pınar, Mustafa Ç.; Bozkaya, Efe B.

2013-01-01

An American option (or, warrant) is the right, but not the obligation, to purchase or sell an underlying equity at any time up to a predetermined expiration date for a predetermined amount. A perpetual American option differs from a plain American option in that it does not expire. In this study, we solve the optimal stopping problem of a perpetual American option (both call and put) in discrete time using linear programming duality. Under the assumption that the underlying stock price follows a discrete time and discrete state Markov process, namely a geometric random walk, we formulate the pricing problem as an infinite dimensional linear programming (LP) problem using the excessive-majorant property of the value function. This formulation allows us to solve complementary slackness conditions in closed-form, revealing an optimal stopping strategy which highlights the set of stock-prices where the option should be exercised. The analysis for the call option reveals that such a critical value exists only in some cases, depending on a combination of state-transition probabilities and the economic discount factor (i.e., the prevailing interest rate) whereas it ceases to be an issue for the put.

Discrete-Time Pricing and Optimal Exercise of American Perpetual Warrants in the Geometric Random Walk Model

Energy Technology Data Exchange (ETDEWEB)

Vanderbei, Robert J., E-mail: rvdb@princeton.edu [Princeton University, Department of Operations Research and Financial Engineering (United States); P Latin-Small-Letter-Dotless-I nar, Mustafa C., E-mail: mustafap@bilkent.edu.tr [Bilkent University, Department of Industrial Engineering (Turkey); Bozkaya, Efe B. [Sabanc Latin-Small-Letter-Dotless-I University, Faculty of Administrative Sciences (Turkey)

2013-02-15

An American option (or, warrant) is the right, but not the obligation, to purchase or sell an underlying equity at any time up to a predetermined expiration date for a predetermined amount. A perpetual American option differs from a plain American option in that it does not expire. In this study, we solve the optimal stopping problem of a perpetual American option (both call and put) in discrete time using linear programming duality. Under the assumption that the underlying stock price follows a discrete time and discrete state Markov process, namely a geometric random walk, we formulate the pricing problem as an infinite dimensional linear programming (LP) problem using the excessive-majorant property of the value function. This formulation allows us to solve complementary slackness conditions in closed-form, revealing an optimal stopping strategy which highlights the set of stock-prices where the option should be exercised. The analysis for the call option reveals that such a critical value exists only in some cases, depending on a combination of state-transition probabilities and the economic discount factor (i.e., the prevailing interest rate) whereas it ceases to be an issue for the put.

Matter of 381 Search Warrants Directed to Facebook, 2017 N.Y. Lexis 767, 2; 2017 NY Slip op. 02586, 2 (N.Y. April 4, 2017

Directory of Open Access Journals (Sweden)

Trad. Leopoldo Villar

2017-08-01

Full Text Available The growing importance of electronic communications gives a special interest to its protection, which involves several fundamental rights and guarantees such as freedom, privacy and property. Due to the importance of the discussion and the different positions it reflects on an issue of such sensitivity and pertinence in the world today, we publish below the translation of the decision by the Supreme Court of the State of New York of April 4, 2017, on the 381 search warrants directed to Facebook user accounts, ordered by the same Court in 2013 in response to a request by the New York County District Attorney, supported in turn by an affidavit given by a prosecutor in a criminal investigation. Facebook filed a motion seeking annulment of the search warrants and disclosure of the Prosecutor’s affidavit but both motions were rejected by the Appeals Division, whereupon Facebook appealed to the New York Supreme Court, which dismissed the appeal. Although most agreed that the appeal was not appropriate, the views of the judges contain interpretations that make their reading very useful and particularly the opinión given by the dissenting judge offers enriching arguments for defending the rights of users of electronic services.

GENERAL PRINCIPLES OF EU (CRIMINAL LAW: LEGALITY, EQUALITY, NON-DISCRIMINATION, SPECIALTY AND NE BIS IN IDEM IN THE FIELD OF THE EUROPEAN ARREST WARRANT

Directory of Open Access Journals (Sweden)

NOREL NEAGU

2012-05-01

Full Text Available This article deals with the case law of the Court of Justice of the European Union in the field of the European arrest warrant, critically analysing the principles invoked in several decisions validating the European legislation in the field: legality, equality and non-discrimination, specialty, ne bis in idem. The author concludes that an area of freedom, security and justice could be built on these principles, but further harmonisation of legislation needs to be realised to avoid a ”journey to the unknown” for European citizens in respect to legislation of other member states of the EU.

Measuring the Effect of Housing Quality Interventions: The Case of the New Zealand "Rental Warrant of Fitness".

Science.gov (United States)

Telfar-Barnard, Lucy; Bennett, Julie; Howden-Chapman, Philippa; Jacobs, David E; Ormandy, David; Cutler-Welsh, Matthew; Preval, Nicholas; Baker, Michael G; Keall, Michael

2017-11-07

In New Zealand, as in many other countries, housing in the private-rental sector is in worse condition than in the owner-occupier housing sector. New Zealand residential buildings have no inspection regime after original construction signoff. Laws and regulations mandating standards for existing residential housing are outdated and spread over a range of instruments. Policies to improve standards in existing housing have been notoriously difficult to implement. In this methods paper, we describe the development and implementation of a rental Warrant of Fitness (WoF) intended to address these problems. Dwellings must pass each of 29 criteria for habitability, insulation, heating, ventilation, safety, amenities, and basic structural soundness to reach the WoF minimum standard. The WoF's development was based on two decades of research on the impact of housing quality on health and wellbeing, and strongly influenced by the UK Housing Health and Safety Rating System and US federal government housing standards. Criteria were field-tested across a range of dwelling types and sizes, cities, and climate zones. The implementation stage of our WoF research consists of a non-random controlled quasi-experimental study in which we work with two city-level local government councils to implement the rental WoF, recruiting adjoining council areas as controls, and measuring changes in health, economic, and social outcomes.

High-fertility phenotypes: two outbred mouse models exhibit substantially different molecular and physiological strategies warranting improved fertility.

Science.gov (United States)

Langhammer, Martina; Michaelis, Marten; Hoeflich, Andreas; Sobczak, Alexander; Schoen, Jennifer; Weitzel, Joachim M

2014-01-01

Animal models are valuable tools in fertility research. Worldwide, there are more than 400 transgenic or knockout mouse models available showing a reproductive phenotype; almost all of them exhibit an infertile or at least subfertile phenotype. By contrast, animal models revealing an improved fertility phenotype are barely described. This article summarizes data on two outbred mouse models exhibiting a 'high-fertility' phenotype. These mouse lines were generated via selection over a time period of more than 40 years and 161 generations. During this selection period, the number of offspring per litter and the total birth weight of the entire litter nearly doubled. Concomitantly with the increased fertility phenotype, several endocrine parameters (e.g. serum testosterone concentrations in male animals), physiological parameters (e.g. body weight, accelerated puberty, and life expectancy), and behavioral parameters (e.g. behavior in an open field and endurance fitness on a treadmill) were altered. We demonstrate that the two independently bred high-fertility mouse lines warranted their improved fertility phenotype using different molecular and physiological strategies. The fertility lines display female- as well as male-specific characteristics. These genetically heterogeneous mouse models provide new insights into molecular and cellular mechanisms that enhance fertility. In view of decreasing fertility in men, these models will therefore be a precious information source for human reproductive medicine. Translated abstract A German translation of abstract is freely available at http://www.reproduction-online.org/content/147/4/427/suppl/DC1.

Transforming Warrant Officer Career College Instructor Assessment for the Army Learning Model

Science.gov (United States)

2014-09-01

Career College (WOCC) to reflect the Army Learning Model (ALM)’s emphasis on adult pedagogical approaches. An instructor guide was also developed to...and digital communications, building of effective relationships through interpersonal tact, influence, and communication. • Critical thinking and...students to learn. Foster respect and rapport in the instructor-student relationship and the student-student relationship . Encourage student

Measuring the Effect of Housing Quality Interventions: The Case of the New Zealand “Rental Warrant of Fitness”

Science.gov (United States)

Telfar-Barnard, Lucy; Bennett, Julie; Howden-Chapman, Philippa; Jacobs, David E.; Ormandy, David; Cutler-Welsh, Matthew; Preval, Nicholas; Baker, Michael G.; Keall, Michael

2017-01-01

In New Zealand, as in many other countries, housing in the private-rental sector is in worse condition than in the owner-occupier housing sector. New Zealand residential buildings have no inspection regime after original construction signoff. Laws and regulations mandating standards for existing residential housing are outdated and spread over a range of instruments. Policies to improve standards in existing housing have been notoriously difficult to implement. In this methods paper, we describe the development and implementation of a rental Warrant of Fitness (WoF) intended to address these problems. Dwellings must pass each of 29 criteria for habitability, insulation, heating, ventilation, safety, amenities, and basic structural soundness to reach the WoF minimum standard. The WoF’s development was based on two decades of research on the impact of housing quality on health and wellbeing, and strongly influenced by the UK Housing Health and Safety Rating System and US federal government housing standards. Criteria were field-tested across a range of dwelling types and sizes, cities, and climate zones. The implementation stage of our WoF research consists of a non-random controlled quasi-experimental study in which we work with two city-level local government councils to implement the rental WoF, recruiting adjoining council areas as controls, and measuring changes in health, economic, and social outcomes. PMID:29112147

Measuring the Effect of Housing Quality Interventions: The Case of the New Zealand “Rental Warrant of Fitness”

Directory of Open Access Journals (Sweden)

Lucy Telfar-Barnard

2017-11-01

Full Text Available In New Zealand, as in many other countries, housing in the private-rental sector is in worse condition than in the owner-occupier housing sector. New Zealand residential buildings have no inspection regime after original construction signoff. Laws and regulations mandating standards for existing residential housing are outdated and spread over a range of instruments. Policies to improve standards in existing housing have been notoriously difficult to implement. In this methods paper, we describe the development and implementation of a rental Warrant of Fitness (WoF intended to address these problems. Dwellings must pass each of 29 criteria for habitability, insulation, heating, ventilation, safety, amenities, and basic structural soundness to reach the WoF minimum standard. The WoF’s development was based on two decades of research on the impact of housing quality on health and wellbeing, and strongly influenced by the UK Housing Health and Safety Rating System and US federal government housing standards. Criteria were field-tested across a range of dwelling types and sizes, cities, and climate zones. The implementation stage of our WoF research consists of a non-random controlled quasi-experimental study in which we work with two city-level local government councils to implement the rental WoF, recruiting adjoining council areas as controls, and measuring changes in health, economic, and social outcomes.

'Thinking ill of others without sufficient warrant?' Transcending the accuracy-inaccuracy dualism in prejudice and stereotyping research.

Science.gov (United States)

Dixon, John

2017-03-01

Research on prejudice seeks to understand and transform inaccurate beliefs about others. Indeed, historically such research has offered a cautionary tale of the biased nature of human cognition. Recently, however, this view has been challenged by work defending the essential rationality of intergroup perception, a theme captured controversially in Jussim and colleagues' (2009) research on the 'unbearable accuracy of stereotyping'. The present paper argues that in its own terms the 'rationalist turn' in socio-cognitive research on stereotyping presents an important challenge to the prejudice tradition, raising troubling questions about its conceptual and empirical foundations. However, it also argues for the necessity of transcending those terms. By focusing on the correspondence between individual beliefs and the supposedly 'objective' characteristics of others, we neglect the historical and discursive practices through which the social realities that we 'perceive' are actively constructed and institutionalized. We mask their social origins, contested and perspectival nature, relativity, and relationship to wider structures of power. By implication, moving beyond the Allportian perspective that has dominated both the prejudice tradition and the emerging stereotype accuracy paradigm, we may now need to prioritize other kinds of questions. Reversing Allport's famous definition of prejudice, it may now be time to ask: How, and with what consequences, does 'thinking ill of others' become sufficiently warranted? How does such thinking become part of institutionalized relations of power and an accepted way of perceiving, evaluating and treating others? What should social psychologists be doing to challenge this state of affairs? © 2017 The British Psychological Society.

Does the health status of intimate partner violence victims warrant pharmacies as portals for public health promotion?

Science.gov (United States)

Cerulli, Catherine; Cerulli, Jennifer; Santos, Elizabeth J; Lu, Najii; He, Hua; Kaukeinen, Kimberly; White, Anne Marie; Tu, Xin

To explore whether the health status of intimate partner violence (IPV) victims warrants pharmacies to be portals for public health promotion. Specific objectives included (1) identifying prevalence of IPV including domestic violence (DV) and sexual assault (SA) in a community sample, (2) describing characteristics and correlates of DV/SA between participants who reported and did not report DV/SA, and (3) exploring whether DV/SA status is related to mental health medication use. Cross sectional. Upstate New York during 2006. English- and Spanish-speaking respondents younger than 65 years of age answering four questions to assess DV/SA. Secondary analysis of a countywide random telephone survey, the 2006 Monroe County Adult Health Survey, which collects prevalence data on health behaviors and health status indicators. To determine whether those reporting DV/SA are at increased odds for mental health medication use, controlling for other sociodemographic- and health-related variables. The survey response rate was 30.3%, with 1,881 respondents meeting inclusion criteria. Those reporting DV/SA were almost twice as likely to use mental health medications. However, when controlling for other variables, only poor mental and physical health were significant in increasing the odds of mental health medication use. The analyses reported here suggest that DV/SA victims in a community sample use mental health medications. When controlling for other variables, survey respondents reported worse physical and mental health. If pharmacies are suitable portals for DV/SA outreach, curricula would need to provide the knowledge and skills needed to take an active role in this public health promotion.

Developing Air Defense Artillery Warrant Officers Cognitive Skills: An Analysis of Training Needs

Science.gov (United States)

2018-02-01

Northrop Grumman Corporation 3565 Macon Road Columbus, GA 31907 8. PERFORMING ORGANIZATION REPORT NUMBER...coordinating the activities of enhanced operators for the maintenance of computers, commercial off the shelf and common hardware and software including...contingency missions. They advise the commander on capabilities and limitations of the AMD system. They supervise maintenance of equipment in AMD units as

What Do Trainers Need to Know to Train Higher-Order Thinking Skills

Science.gov (United States)

2017-11-01

training at the Warrant Officer Career College (WOCC) in Fort Rucker, AL. The WOCC trains all warrant officers through the Warrant Officer Candidate...who are early in their careers . For Patriot, direct instruction could include training focused on the steps required to emplace the system and make...ADEA) (2015). Overview of Critical Thinking Skills. Retrieved from http://www.adea.org/adeacci/Resources/Critical-Thinking-Skills- Toolkit /Pages

West Nile Virus: High Transmission Rate in North-Western European Mosquitoes Indicates Its Epidemic Potential and Warrants Increased Surveillance.

Directory of Open Access Journals (Sweden)

Jelke J Fros

Full Text Available West Nile virus (WNV is a highly pathogenic flavivirus transmitted by Culex spp. mosquitoes. In North America (NA, lineage 1 WNV caused the largest outbreak of neuroinvasive disease to date, while a novel pathogenic lineage 2 strain circulates in southern Europe. To estimate WNV lineage 2 epidemic potential it is paramount to know if mosquitoes from currently WNV-free areas can support further spread of this epidemic.We assessed WNV vector competence of Culex pipiens mosquitoes originating from north-western Europe (NWE in direct comparison with those from NA. We exposed mosquitoes to infectious blood meals of lineage 1 or 2 WNV and determined the infection and transmission rates. We explored reasons for vector competence differences by comparing intrathoracic injection versus blood meal infection, and we investigated the influence of temperature. We found that NWE mosquitoes are highly competent for both WNV lineages, with transmission rates up to 25%. Compared to NA mosquitoes, transmission rates for lineage 2 WNV were significantly elevated in NWE mosquitoes due to better virus dissemination from the midgut and a shorter extrinsic incubation time. WNV infection rates further increased with temperature increase.Our study provides experimental evidence to indicate markedly different risk levels between both continents for lineage 2 WNV transmission and suggests a degree of genotype-genotype specificity in the interaction between virus and vector. Our experiments with varying temperatures explain the current localized WNV activity in southern Europe, yet imply further epidemic spread throughout NWE during periods with favourable climatic conditions. This emphasizes the need for intensified surveillance of virus activity in current WNV disease-free regions and warrants increased awareness in clinics throughout Europe.

Predictive factors warrant screening for obstructive sleep apnea in COPD: a Taiwan National Survey

Directory of Open Access Journals (Sweden)

Hang LW

2016-03-01

questionnaire to assess COPD symptoms and OSA risk, comorbidities, and performance of daily activities. Data from COPD cohorts with and without risk of OSA were analyzed and compared. Results: Of 6,600 interviews completed, 404 subjects fit the epidemiological case definition of COPD – an overall prevalence of 6.1% in this national sample. Data on OSA risk were available for 292 of this COPD cohort, of whom 29.5% were at risk of OSA. Compared to those without risk of OSA, those with risk of OSA were significantly more likely to have hypertension or cardiovascular disease and diabetes, had significantly higher body mass index and COPD Assessment Test scores, and reported impaired work performance and leisure activities. Conclusion: Among adults in Taiwan who fulfill epidemiologic criteria for COPD, 29.5% have coexisting risk of OSA. Comorbid hypertension or cardiovascular disease and diabetes are common and significantly more prevalent among the COPD population at risk of OSA than those who are not. OSA screening is warranted in patients with COPD with those risk factors that are more prevalent in COPD with risk of OSA than without, to target early interventions to reduce adverse cardiovascular sequelae from overlap syndrome. Keywords: cardiovascular risk, COPD, coexistent, obstructive sleep apnea, OSA, overlap syndrome

Risk of breast cancer after a diagnosis of ovarian cancer in BRCA mutation carriers: Is preventive mastectomy warranted?

Science.gov (United States)

McGee, Jacob; Giannakeas, Vasily; Karlan, Beth; Lubinski, Jan; Gronwald, Jacek; Rosen, Barry; McLaughlin, John; Risch, Harvey; Sun, Ping; Foulkes, William D; Neuhausen, Susan L; Kotsopoulos, Joanne; Narod, Steven A

2017-05-01

Preventive breast surgery and MRI screening are offered to unaffected BRCA mutation carriers. The clinical benefit of these two modalities has not been evaluated among mutation carriers with a history of ovarian cancer. Thus, we sought to determine whether or not BRCA mutation carriers with ovarian cancer would benefit from preventive mastectomy or from MRI screening. First, the annual mortality rate for ovarian cancer patients was estimated for a cohort of 178 BRCA mutation carriers from Ontario, Canada. Next, the actuarial risk of developing breast cancer was estimated using an international registry of 509 BRCA mutation carriers with ovarian cancer. A series of simulations was conducted to evaluate the reduction in the probability of death (from all causes) associated with mastectomy and with MRI-based breast surveillance. Cox proportional hazards models were used to evaluate the impacts of mastectomy and MRI screening on breast cancer incidence as well as on all-cause mortality. Twenty (3.9%) of the 509 patients developed breast cancer within ten years following ovarian cancer diagnosis. The actuarial risk of developing breast cancer at ten years post-diagnosis, conditional on survival from ovarian cancer and other causes of mortality was 7.8%. Based on our simulation results, among all BRCA mutation-carrying patients diagnosed with stage III/IV ovarian cancer at age 50, the chance of dying before age 80 was reduced by less than 1% with MRI and by less than 2% with mastectomy. Greater improvements in survival with MRI or mastectomy were observed for women who had already survived 10years after ovarian cancer, and for women with stage I or II ovarian cancer. Among BRCA mutation-carrying ovarian cancer patients without a personal history of breast cancer, neither preventive mastectomy nor MRI screening is warranted, except for those who have survived ovarian cancer without recurrence for ten years and for those with early stage ovarian cancer. Copyright © 2017

Is a comparative clinical trial for breast cancer tumor markers to monitor disease recurrence warranted? A value of information analysis.

Science.gov (United States)

Thariani, Rahber; Henry, Norah Lynn; Ramsey, Scott D; Blough, David K; Barlow, Bill; Gralow, Julie R; Veenstra, David L

2013-05-01

Breast cancer tumor markers are used by some clinicians to screen for disease recurrence risk. Since there is limited evidence of benefit, additional research may be warranted. To assess the potential value of a randomized clinical trial of breast tumor marker testing in routine follow-up of high-risk, stage II-III breast cancer survivors. We developed a decision-analytic model of tumor marker testing plus standard surveillance every 3-6 months for 5 years. The expected value of sample information was calculated using probabilistic simulations and was a function of: the probability of selecting the optimal monitoring strategy with current versus future information; the impact of choosing the nonoptimal strategy; and the size of the population affected. The value of information for a randomized clinical trial involving 9000 women was US$214 million compared with a cost of US$30-60 million to conduct such a trial. The probability of making an alternate, nonoptimal decision and choosing testing versus no testing was 32% with current versus future information from the trial. The impact of a nonoptimal decision was US$2150 and size of population impacted over 10 years was 308,000. The value of improved information on overall survival was US$105 million, quality of life US$37 million and test performance US$71 million. Conducting a randomized clinical trial of breast cancer tumor markers appears to offer a good societal return on investment. Retrospective analyses to assess test performance and evaluation of patient quality of life using tumor markers may also offer valuable areas of research. However, alternative investments may offer even better returns in investments and, as such, the trial concept deserves further study as part of an overall research-portfolio evaluation.

The European Arrest Warrant in the Italian legal system. Between mutual recognition and mutual fear within the European area of Freedom, Security and Justice

Directory of Open Access Journals (Sweden)

Franco Impalà

2005-12-01

Full Text Available Italy was the last Member State to transpose the Framework Decision on the European Arrest Warrant. The Italian law entered into full force on 14 May 2005, a full sixteen months later than the appointed date. Conversely, whilst the Framework Decision aimed to speed up extradition between Member States, the Italian implementation law seems to complicate things, providing for dozens of new legal obstacles to surrender. In fact, the execution of an EAW in Italy threatens to become something highly unpredictable. The responsibility for this outcome is shared by the national and the European legislator. Perhaps the latter underestimated the seriousness of the conflict between Third Pillar law and domestic constitutional systems which aim to protect their acquis in the field of fundamental rights. Considering that many Member States seem to be struggling with similar problems, the first part of this article is devoted to describing the current scenario and analysing possible solutions at the supranational level, such as the establishment of a coherent system regulating the allocation of penal competences among Member States. In the next part, the problem of the Framework Decision’s incompatibility with the Italian Constitution will be discussed, and in the final part the Italian implementation law is analysed in more detail.

Bioactive endophytes warrant intensified exploration and conservation.

Science.gov (United States)

Smith, Stephen A; Tank, David C; Boulanger, Lori-Ann; Bascom-Slack, Carol A; Eisenman, Kaury; Kingery, David; Babbs, Beatrice; Fenn, Kathleen; Greene, Joshua S; Hann, Bradley D; Keehner, Jocelyn; Kelley-Swift, Elizabeth G; Kembaiyan, Vivek; Lee, Sun Jin; Li, Puyao; Light, David Y; Lin, Emily H; Ma, Cong; Moore, Emily; Schorn, Michelle A; Vekhter, Daniel; Nunez, Percy V; Strobel, Gary A; Donoghue, Michael J; Strobel, Scott A

2008-08-25

A key argument in favor of conserving biodiversity is that as yet undiscovered biodiversity will yield products of great use to humans. However, the link between undiscovered biodiversity and useful products is largely conjectural. Here we provide direct evidence from bioassays of endophytes isolated from tropical plants and bioinformatic analyses that novel biology will indeed yield novel chemistry of potential value. We isolated and cultured 135 endophytic fungi and bacteria from plants collected in Peru. nrDNAs were compared to samples deposited in GenBank to ascertain the genetic novelty of cultured specimens. Ten endophytes were found to be as much as 15-30% different than any sequence in GenBank. Phylogenetic trees, using the most similar sequences in GenBank, were constructed for each endophyte to measure phylogenetic distance. Assays were also conducted on each cultured endophyte to record bioactivity, of which 65 were found to be bioactive. The novelty of our contribution is that we have combined bioinformatic analyses that document the diversity found in environmental samples with culturing and bioassays. These results highlight the hidden hyperdiversity of endophytic fungi and the urgent need to explore and conserve hidden microbial diversity. This study also showcases how undergraduate students can obtain data of great scientific significance.

Bioactive endophytes warrant intensified exploration and conservation.

Directory of Open Access Journals (Sweden)

Stephen A Smith

2008-08-01

Full Text Available A key argument in favor of conserving biodiversity is that as yet undiscovered biodiversity will yield products of great use to humans. However, the link between undiscovered biodiversity and useful products is largely conjectural. Here we provide direct evidence from bioassays of endophytes isolated from tropical plants and bioinformatic analyses that novel biology will indeed yield novel chemistry of potential value.We isolated and cultured 135 endophytic fungi and bacteria from plants collected in Peru. nrDNAs were compared to samples deposited in GenBank to ascertain the genetic novelty of cultured specimens. Ten endophytes were found to be as much as 15-30% different than any sequence in GenBank. Phylogenetic trees, using the most similar sequences in GenBank, were constructed for each endophyte to measure phylogenetic distance. Assays were also conducted on each cultured endophyte to record bioactivity, of which 65 were found to be bioactive.The novelty of our contribution is that we have combined bioinformatic analyses that document the diversity found in environmental samples with culturing and bioassays. These results highlight the hidden hyperdiversity of endophytic fungi and the urgent need to explore and conserve hidden microbial diversity. This study also showcases how undergraduate students can obtain data of great scientific significance.

The nuclear pacemaker: Is renewed interest warranted

International Nuclear Information System (INIS)

Parsonnet, V.; Berstein, A.D.; Perry, G.Y.

1990-01-01

From 1973 through 1987, 155 radioisotope-powered nuclear pacemakers were implanted in 132 patients at the Newark Beth Israel Medical Center. The longevity of the first 15 devices, all of which were fixed-rate (VOO) pacemakers, was significantly better than that of 15 lithium-chemistry demand (VVI) pacemakers used as control devices (p = 0.0002). Of the entire cohort of 155 nuclear pacemakers, 136 were VVI devices and 19 were VOO units. The patients with VOO pacemakers needed reoperations more often than did those with VVI pacemakers, chiefly for mode change (p less than 0.001). Power-source failure was observed in only 1 case, but 47 nuclear pacemakers were removed for other reasons, including component malfunction (15 units), mode change (12 units), high pacing thresholds (8 units) and lead or connector problems (5 units). The actuarial survival at 15 years was 99% for power sources and 82% for the entire pacing systems (pulse generators plus leads). The frequency of malignancy was similar to that of the population at large and primary tumor sites were randomly distributed. Deaths most commonly were due to cardiac causes (68%). Thus, nuclear pacemakers are safe and reliable and their greater initial cost appears to be offset by their longevity and the resulting decrease in the frequency of reoperations. It is reasonable to suggest that further use be made of long-lasting nuclear power sources for modern pacemakers and other implantable rhythm-management devices

When does atopic dermatitis warrant systemic therapy?

DEFF Research Database (Denmark)

Simpson, Eric L; Bruin-Weller, Marjolein; Flohr, Carsten

2017-01-01

therapy in AD and provide a framework for evaluation before making this therapeutic decision with the patient. METHODS: A subgroup of the International Eczema Council determined aspects to consider before prescribing systemic therapy. Topics were assigned to expert reviewers who performed a topic...... systemic therapy include considering alternate or concomitant diagnoses, avoiding trigger factors, optimizing topical therapy, ensuring adequate patient/caregiver education, treating coexistent infection, assessing the impact on quality of life, and considering phototherapy. LIMITATIONS: Our work...

Greenhouse gas reductions; not warranted, not beneficial

International Nuclear Information System (INIS)

Green, K.

2003-01-01

This report deals with climate change and greenhouse gas emissions, especially regional climate change predictions, from a sceptic's point of view. It rejects all the conventional evidence supporting claims of extreme man-made climate changes, dismissing them as alarmist and inherently uncertain. Similarly, it characterizes policy prescriptions based on this evidence as faulty and as measures which, if implemented, would do both current and future generations considerably more harm than good. Calls for energy efficiency and conservation, reliance on renewable energy sources, improved efficiency of conventional vehicles, hybrid and fuel-cell-driven cars, reducing the amount of driving, establishing greenhouse gas registries, are all dismissed as impractical, imposing higher costs on energy generally, slowing economic growth in the process, and scaring people to adopt unwise public policies by exaggerating the certainty of predictions about man-made climate change. While dismissing the arguments advanced by 'old-school' environmentalists, the report does not question the validity of the overall theory or details of the core greenhouse effect, its main targets are the anthropogenic components of the observed temperature record, and the evidence of a clear cause-and-effect link between anthropogenic forcing and changes in the Earth's surface temperature. Overall, the report dismisses the 'conventional' view of the extent of climate change, the cause of that change and the risk it poses. It emphasizes the limitations on economic freedom that proposed policies would inflict, and argues in favour of more studies to provide the foundation for a societal response based on a solid understanding of the science behind climate change, and the impact of proposed policy options. 32 refs., 2 figs

Measuring Distribution Performance? Benchmarking Warrants Your Attention

Energy Technology Data Exchange (ETDEWEB)

Ericson, Sean J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Alvarez, Paul [The Wired Group

2018-04-13

Identifying, designing, and measuring performance metrics is critical to securing customer value, but can be a difficult task. This article examines the use of benchmarks based on publicly available performance data to set challenging, yet fair, metrics and targets.

When does atopic dermatitis warrant systemic therapy?

DEFF Research Database (Denmark)

Simpson, Eric L; Bruin-Weller, Marjolein; Flohr, Carsten

2017-01-01

-specific literature review, referred to guidelines when available, and provided interpretation and expert opinion. RESULTS: We recommend a systematic and holistic approach to assess patients with severe signs and symptoms of AD and impact on quality of life before systemic therapy. Steps taken before commencing......BACKGROUND: Although most patients with atopic dermatitis (AD) are effectively managed with topical medication, a significant minority require systemic therapy. Guidelines for decision making about advancement to systemic therapy are lacking. OBJECTIVE: To guide those considering use of systemic...... therapy in AD and provide a framework for evaluation before making this therapeutic decision with the patient. METHODS: A subgroup of the International Eczema Council determined aspects to consider before prescribing systemic therapy. Topics were assigned to expert reviewers who performed a topic...

A Descriptive Analysis of Occupational Fatalities Due to Felonious Assault Among U.S. Law Enforcement Officers During Tactical Incidents, 1996-2014.

Science.gov (United States)

Thompson, Moriah S; Hartman, Tyler M; Sztajnkrycer, Matthew D

Little is known about occupational fatalities among tactical officers. A greater understanding of such injuries is needed to improve officer safety. The purpose of this study was to provide a descriptive analysis of line-of-duty deaths secondary to felonious assault during tactical incidents. Retrospective analysis was performed of open-source de-identified Federal Bureau of Investigation Uniform Crime Reporting Law Enforcement Officers Killed and Assaulted (LEOKA) data inclusive of the years 1996-2014. Officers were included if the fatal injury occurred during operations by a Special Weapons and Tactics (SWAT) team, fugitive task force, narcotics task force, or if the LEOKA narrative described the event as a tactical situation. Of 1,012 officer deaths during the study period, 57 (5.6%) involved tactical officers. On average (± standard deviation), victim officers were 37.3 ± 7.8 years of age at the time of death, with 11.7 ± 6.6 years of law enforcement experience. High-risk warrant service accounted for 63.2% of fatalities. A single officer was killed in 91.2% of incidents; 49.1% of cases involved injuries to other officers. The majority of officers (59.6%) killed were the first officer(s) to enter the scene. The most commonly identified cause of death was head trauma (n = 28). Chest trauma accounted for 14 deaths; 10 (71.4%) sustained an entry wound via the ballistic vest armhole. Where recorded, 52.0% of officers died within the first hour of injury. The provision or nature of buddy care, tactical emergency medical services (EMS) care, or conventional EMS care was rarely noted. Tactical officer deaths most commonly occur during high-risk warrant service, and most often involve the first officer(s) to enter a scene, suggesting an opportunity for improved operational tactics. The frequency of fatal axillary penetration suggests the opportunity for ballistic protection redesign. Information is lacking regarding on-scene care, limiting the ability to determine

Fumigant emission reductions with TIF warrant regulatory changes

Directory of Open Access Journals (Sweden)

Husein Ajwa

2013-07-01

Full Text Available With methyl bromide's phase-out, most growers have turned to alternative fumigants, particularly 1,3-dichloropropene (1,3-D and chloropicrin. These alternatives are tightly regulated because they are classified as toxic air contaminants and volatile organic compounds; the latter combine with other substances to produce ground-level ozone (smog. Two ambient air monitoring studies were conducted to evaluate the potential of totally impermeable film (TIF to reduce emissions from shank applications of chloropicrin and 1,3-D. In 2009, a study demonstrated that TIF reduced chloropicrin and 1,3-D peak emissions by 45% and 38%, respectively, but TIF did not reduce total emissions when it was cut after 6 days. In 2011, increasing the tarp period from 5 to 10 days decreased chloropicrin and 1,3-D peak emissions by 88% and 78%, and their total emissions by 64% and 43%, respectively. Concurrent dynamic flux chamber results corroborated the ambient air monitoring data. These studies provide regulatory agencies with mitigation measures that should allow continued fumigant use at efficacious application rates.

The Warrant for Constructivist Practice within Educational Technology.

Science.gov (United States)

Bopry, Jeanette

1999-01-01

Discusses educational technology as a form of technical rationality and considers the conflict between practitioners' epistemological position as constructivists and technical rationality. Topics include cybernetics; autonomous systems theory; enactive constructivism; representation versus effective action; mind and memory; enaction in artificial…

Students Build Mathematical Theory: Semantic Warrants in Argumentation

Science.gov (United States)

Walter, Janet G.; Barros, Tara

2011-01-01

In this paper, we explore the development of two grounded theories. One theory is mathematical and grounded in the work of university calculus students' collaborative development of mathematical methods for finding the volume of a solid of revolution, in response to mathematical necessity in problem solving, without prior instruction on solution…

Adult-onset offenders: Is a tailored theory warranted?

Science.gov (United States)

Beckley, Amber L.; Caspi, Avshalom; Harrington, Honalee; Houts, Renate M.; Mcgee, Tara Renae; Morgan, Nick; Schroeder, Felix; Ramrakha, Sandhya; Poulton, Richie; Moffitt, Terrie E.

2016-01-01

Purpose To describe official adult-onset offenders, investigate their antisocial histories and test hypotheses about their origins. Methods We defined adult-onset offenders among 931 Dunedin Study members followed to age 38, using criminal-court conviction records. Results Official adult-onset offenders were 14% of men, and 32% of convicted men, but accounted for only 15% of convictions. As anticipated by developmental theories emphasizing early-life influences on crime, adult-onset offenders’ histories of antisocial behavior spanned back to childhood. Relative to juvenile-offenders, during adolescence they had fewer delinquent peers and were more socially inhibited, which may have protected them from conviction. As anticipated by theories emphasizing the importance of situational influences on offending, adult-onset offenders, relative to non-offenders, during adulthood more often had schizophrenia, bipolar disorder, and alcohol-dependence, had weaker social bonds, anticipated fewer informal sanctions, and self-reported more offenses. Contrary to some expectations, adult-onset offenders did not have high IQ or high socioeconomic-status families protecting them from juvenile conviction. Conclusions A tailored theory for adult-onset offenders is unwarranted because few people begin crime de novo as adults. Official adult-onset offenders fall on a continuum of crime and its correlates, between official non-offenders and official juvenile-onset offenders. Existing theories can accommodate adult-onset offenders. PMID:27134318

48 CFR 801.690-3 - Responsibilities under the COCP.

Science.gov (United States)

2010-10-01

... appointment of contracting officers at the Micro-purchase Level and Level I warrant level within their... of appointment of purchase card holders at the Micro-purchase Level and Level I warrant contracting... acquisition training, continuing education, college transcripts, work experience, and other supporting...

Works scheduling. Warranting the availability of your facilities is one of our daily challenge. Scheduling our works with you favors this availability; Programmation des travaux. Garantir la disponibilite de vos installations constitue l'un de nos defis quotidiens. Programmer nos travaux avec vous favorise cette disponibilite

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-12-01

One of the missions of the French manager of the power transportation grid (RTE) is to maintain and improve the performance of the network in order to warrant the security and quality of power supplies. Thus, any maintenance or development works leading to the unavailableness of the client's power connection requires a precise scheduling of these works. The aim of this brochure is to describe the procedure to follow in this case. (J.S.)

Becoming a Graduate: The Warranting of an Emergent Identity

Science.gov (United States)

Holmes, Leonard M.

2015-01-01

Purpose: With expansion of higher education in most developed and developing economies, graduates constitute a large section of the workforce. However, even prior to the economic problems of the past few years, the transition from higher education into graduate employment has not been and is not straightforward. The purpose of this paper is to…

Symbols and warrants for major traffic generator guide signing.

Science.gov (United States)

2009-09-01

The Texas Manual on Uniform Traffic Control Devices (TMUTCD) provides the definition of regular traffic generators based on four population types but not for major traffic generators (MTGs). MTG signs have been considered to supplement the overall si...

Temperature impacts on economic growth warrant stringent mitigation policy

Science.gov (United States)

Moore, Frances C.; Diaz, Delavane B.

2015-02-01

Integrated assessment models compare the costs of greenhouse gas mitigation with damages from climate change to evaluate the social welfare implications of climate policy proposals and inform optimal emissions reduction trajectories. However, these models have been criticized for lacking a strong empirical basis for their damage functions, which do little to alter assumptions of sustained gross domestic product (GDP) growth, even under extreme temperature scenarios. We implement empirical estimates of temperature effects on GDP growth rates in the DICE model through two pathways, total factor productivity growth and capital depreciation. This damage specification, even under optimistic adaptation assumptions, substantially slows GDP growth in poor regions but has more modest effects in rich countries. Optimal climate policy in this model stabilizes global temperature change below 2 °C by eliminating emissions in the near future and implies a social cost of carbon several times larger than previous estimates. A sensitivity analysis shows that the magnitude of climate change impacts on economic growth, the rate of adaptation, and the dynamic interaction between damages and GDP are three critical uncertainties requiring further research. In particular, optimal mitigation rates are much lower if countries become less sensitive to climate change impacts as they develop, making this a major source of uncertainty and an important subject for future research.

Funding of drugs : do vaccines warrant a different approach?

NARCIS (Netherlands)

Beutels, Philippe; Scuffham, Paul A.; MacIntyre, C. Raina

2008-01-01

Vaccines have features that require special consideration when assessing their cost-effectiveness. These features are related to herd immunity, quality-of-life losses in young children, parental care and work loss, time preference, uncertainty, eradication, macroeconomics, and tiered pricing.

Funding of drugs: do vaccines warrant a different approach?

Science.gov (United States)

Beutels, Philippe; Scuffham, Paul A; MacIntyre, C Raina

2008-11-01

Vaccines have features that require special consideration when assessing their cost-effectiveness. These features are related to herd immunity, quality-of-life losses in young children, parental care and work loss, time preference, uncertainty, eradication, macroeconomics, and tiered pricing. Advisory committees on public funding for vaccines, or for pharmaceuticals in general, should be knowledgable about these special features. We discuss key issues and difficulties in decision making for vaccines against rotavirus, human papillomavirus, varicella-zoster virus, influenza virus, and Streptococcus pneumoniae. We argue that guidelines for economic evaluation should be reconsidered generally to recommend (1) modelling options for the assessment of interventions against infectious diseases; (2) a wider perspective to account for impacts on third parties, if relevant; (3) a wider scope of costs than health-care system costs alone, if appropriate; and (4) alternative discounting techniques to explore social time preference over long periods.

Instability in Thoracolumbar Trauma: Is a New Definition Warranted?

Science.gov (United States)

Abbasi Fard, Salman; Skoch, Jesse; Avila, Mauricio J; Patel, Apar S; Sattarov, Kamran V; Walter, Christina M; Baaj, Ali A

2017-10-01

Review of the articles. The objective of this study was to review all articles related to spinal instability to determine a consensus statement for a contemporary, practical definition applicable to thoracolumbar injuries. Traumatic fractures of the thoracolumbar spine are common. These injuries can result in neurological deficits, disability, deformity, pain, and represent a great economic burden to society. The determination of spinal instability is an important task for spine surgeons, as treatment strategies rely heavily on this assessment. However, a clinically applicable definition of spinal stability remains elusive. A review of the Medline database between 1930 and 2014 was performed limited to papers in English. Spinal instability, thoracolumbar, and spinal stability were used as search terms. Case reports were excluded. We reviewed listed references from pertinent search results and located relevant manuscripts from these lists as well. The search produced a total of 694 published articles. Twenty-five articles were eligible after abstract screening and underwent full review. A definition for spinal instability was described in only 4 of them. Definitions were primarily based on biomechanical and classification studies. No definitive parameters were outlined to define stability. Thirty-six years after White and Panjabi's original definition of instability, and many classification schemes later, there remains no practical and meaningful definition for spinal instability in thoracolumbar trauma. Surgeon expertise and experience remains an important factor in stability determination. We propose that, at an initial assessment, a distinction should be made between immediate and delayed instability. This designation should better guide surgeons in decision making and patient counseling.

48 CFR 842.803 - Disallowing costs after incurrence.

Science.gov (United States)

2010-10-01

... costs after incurrence. Contracting officers may approve or disapprove contractors' vouchers for payment... limitations of the contracting officer's warrant and the contract for which the voucher is submitted must be...

Nonfatal Injuries to Law Enforcement Officers: A Rise in Assaults.

Science.gov (United States)

Tiesman, Hope M; Gwilliam, Melody; Konda, Srinivas; Rojek, Jeff; Marsh, Suzanne

2018-04-01

Limited studies exist that describe nonfatal work-related injuries to law enforcement officers. The aim of this study is to provide national estimates and trends of nonfatal injuries to law enforcement officers from 2003 through 2014. Nonfatal injuries were obtained from the National Electronic Injury Surveillance System-Occupational Supplement. Data were obtained for injuries treated in U.S. emergency departments from 2003 to 2014. Nonfatal injury rates were calculated using denominators from the Current Population Survey. Negative binomial regression was used to analyze temporal trends. Data were analyzed in 2016-2017. Between 2003 and 2014, an estimated 669,100 law enforcement officers were treated in U.S. emergency departments for nonfatal injuries. The overall rate of 635 per 10,000 full-time equivalents was three times higher than all other U.S. workers rate (213 per 10,000 full-time equivalents). The three leading injury events were assaults and violent acts (35%), bodily reactions and exertion (15%), and transportation incidents (14%). Injury rates were highest for the youngest officers, aged 21-24 years. Male and female law enforcement officers had similar nonfatal injury rates. Rates for most injuries remained stable; however, rates for assault-related injuries grew among law enforcement officers between 2003 and 2011. National Electronic Injury Surveillance System-Occupational Supplement data demonstrate a significant upward trend in assault injuries among U.S. law enforcement officers and this warrants further investigation. Police-citizen interactions are dynamic social encounters and evidence-based policing is vital to the health and safety of both police and civilians. The law enforcement community should energize efforts toward the study of how policing tactics impact both officer and citizen injuries. Published by Elsevier Inc.

Right-Turn Traffic Volume Adjustments in Traffic Signal Warrant Analysis

Science.gov (United States)

2015-01-01

To accomplish this research, a comprehensive literature review of existing guidelines and findings based on national and local studies was conducted. Ultimately, guidelines for consistent application for adjusting right-turn traffic volumes were deve...

Is cardiac surgery warranted in children with Down syndrome? A ...

African Journals Online (AJOL)

Objectives. To compare children with Down syndrome and children without Down syndrome and investigate whether there is a significant difference in the burden that is placed on the health care system between these two groups only in respect of the repair of congenital heart disease at Red Cross War Memorial Children's ...

A universal freeze all strategy: why it is not warranted.

Science.gov (United States)

Ata, Baris; Seli, Emre

2017-06-01

There's some preclinical evidence of an adverse effect of multifollicular growth on endometrial function in assisted reproductive technology cycles. Universal elective frozen embryo transfer (eFET) in an unstimulated cycle is being promoted as a panacea, regardless of patient, and cycle characteristics. We review the clinical evidence on the effectiveness and safety of eFETs. Randomized controlled trials (RCTs) comparing fresh and eFET yield contradictory results in terms of live birth rates. RCTs mainly involve women with an excessive response to ovarian stimulation. Studies including women with a normal or low ovarian response are either patient/physician preference or retrospective studies, prone to bias. Yet, they yield contradictory results as well. Overall, eFET seems to have limited potential to improve effectiveness of assisted reproductive technology, which could be limited to hyper-responders. Other suggested advantages of eFET include better obstetric and perinatal outcome. However, recent studies show that frozen embryo transfers can be associated with serious complications including hypertensive disorders during pregnancy, placenta accreta, or increased perinatal mortality. The evidence behind advantages of eFET is of low quality. As such, switching to a universal eFET strategy does not seem justified. New RCTs including women from different strata of ovarian response are needed.

Pediatric near-drowning events: do they warrant trauma team activation?

Science.gov (United States)

Chotai, Pranit N; Manning, Lisa; Eithun, Benjamin; Ross, Joshua C; Eubanks, James W; Hamner, Chad; Gosain, Ankush

2017-05-15

The purpose of this study was to determine the incidence of traumatic injuries, factors associated with mortality, and need for pediatric trauma surgery involvement for drowning and near-drowning events in children. An institutional review board-approved, retrospective chart review was performed at three American College of Surgeons-verified Pediatric Trauma Centers (2011-2014). Patients with International Classification of Diseases, Ninth Revision, codes or E-codes for fatal-nonfatal drowning, fall into water, accidental drowning, or submersion were included. Bivariate analysis using chi-square or Fisher exact test for nominal variables and Mann-Whitney U test for continuous variables was performed. A total of 363 patients (median 3.17 y [18 d-17 y]) met the inclusion criteria. Drowning sites included pool (81.5%), bathtub (12.9%), and natural water (5.2%). A witnessed fall or dive was reported in 34.9%, 57.9% did not fall or dive, and 7% had an unwitnessed event. Most patients did not undergo cervical spine (83%) or brain imaging (75.5%). Seven patients (1.92%) had associated soft tissue injuries. Two patients (0.006%) received surgical intervention (bronchoscopy and extracorporeal membrane oxygenation) within 24 h of presentation. Only 2.2% were admitted to the pediatric trauma service. The percentage of patients discharged home from the emergency department was 10.2%. Overall mortality was 12.4%. Factors associated with mortality included transfer from outside hospital (P = 0.016), presence of hypothermia on arrival (P drowning in a pool (P = 0.013), or undergoing brain cooling at admission (P = 0.011). This is the largest reported series of pediatric near-drowning events. Only rarely did patients require immediate surgical attention and the majority were admitted to nonsurgical services. These data suggest that routine pediatric trauma surgery service involvement in patients with near-drowning events may be unnecessary. Copyright © 2017 Elsevier Inc. All rights reserved.

Do perfume additives termed human pheromones warrant being termed pheromones?

Science.gov (United States)

Winman, Anders

2004-09-30

Two studies of the effects of perfume additives, termed human pheromones by the authors, have conveyed the message that these substances can promote an increase in human sociosexual behaviour [Physiol. Behav. 75 (2003) R1; Arch. Sex. Behav. 27 (1998) R2]. The present paper presents an extended analysis of this data. It is shown that in neither study is there a statistically significant increase in any of the sociosexual behaviours for the experimental groups. In the control groups of both studies, there are, however, moderate but statistically significant decreases in the corresponding behaviour. Most notably, there is no support in data for the claim that the substances increase the attractiveness of the wearers of the substances to the other sex. It is concluded that more research using matched homogenous groups of participants is needed. Copyright 2004 Elsevier Inc.

Symmetry warrants rational cooperation by co-action in Social Dilemmas.

Science.gov (United States)

Sasidevan, V; Sinha, Sitabhra

2015-08-12

Is it rational for selfish individuals to cooperate? The conventional answer based on analysis of games such as the Prisoners Dilemma (PD) is that it is not, even though mutual cooperation results in a better outcome for all. This incompatibility between individual rationality and collective benefit lies at the heart of questions about the evolution of cooperation, as illustrated by PD and similar games. Here, we argue that this apparent incompatibility is due to an inconsistency in the standard Nash framework for analyzing non-cooperative games and propose a new paradigm, that of the co-action equilibrium. As in the Nash solution, agents know that others are just as rational as them and taking this into account lead them to realize that others will independently adopt the same strategy, in contrast to the idea of unilateral deviation central to Nash equilibrium thinking. Co-action equilibrium results in better collective outcomes for games representing social dilemmas, with relatively "nicer" strategies being chosen by rational selfish individuals. In particular, the dilemma of PD gets resolved within this framework, suggesting that cooperation can evolve in nature as the rational outcome even for selfish agents, without having to take recourse to additional mechanisms for promoting it.

Heely injuries: a new epidemic warranting a government health warning!

Science.gov (United States)

Lenehan, B; Callender, O; McIntyre, A; Boran, S; Moore, D; Fogarty, E; Dowling, F

2007-08-01

Heelys, the new craze gripping the nation, were first introduced to Ireland in 2005 having been available in the United States since 2000. Designed as "the only shoe with a removable wheel in the sole" and initially marketed among rollerbladers and skateboarders they have been adopted by children as contemporary footwear. From April to June 2006, all patients presenting to trauma orthopaedic services at our institutions with injuries sustained while wearing Heelys were included in this study. Thirty-nine patients are included in this study. The mean age was 9.1 years (range 7-13, median 9 years). Of the 39 patients referred to the orthopaedic service, 8 required admissions to hospital. One patient admitted following a head injury, required craniotomy and evacuation of an extradural haematoma. The significance of the injuries encountered demonstrates the potentially devastating results from the use of Heelys. The public perception of safety is incorrect and manufacturers rightly recommend strongly the use of safety gear.

77 FR 71796 - Proposed Data Collections Submitted for Public Comment and Recommendations

Science.gov (United States)

2012-12-04

... been limited in laboratory medicine. No single- evidence-based model for recommending practices in... of laboratory tests available certainly warrant such a model. The Laboratory Medicine Best Practices..., 2012. Ron A. Otten, Director, Office of Scientific Integrity (OSI), Office of the Associate Director...

77 FR 55457 - Atlantic Coastal Fisheries Cooperative Management Act Provisions; Horseshoe Crabs; Application...

Science.gov (United States)

2012-09-10

... comments. SUMMARY: The Deputy Director, Office of Sustainable Fisheries, has made a preliminary... Cape May Court House, NJ, contains all the required information and warrants further consideration. The... comments should be sent to Emily Menashes, Deputy Director, Office of Sustainable Fisheries, NMFS, 1315...

75 FR 31421 - Atlantic Coastal Fisheries Cooperative Management Act Provisions; Application for Exempted...

Science.gov (United States)

2010-06-03

... comments. SUMMARY: The Acting Director, Office of Sustainable Fisheries, has made a preliminary... Cape May Court House, New Jersey, contains all the required information and warrants further..., Office of Sustainable Fisheries, NMFS, 1315 East-West Highway, Room 13362, Silver Spring, MD 20910. Mark...

逮捕に伴う電子機器の内容確認と法的規律 : Riley判決を契機として

OpenAIRE

緑, 大輔

2016-01-01

In Riley v. California, the U.S. Supreme Court ruled that police conducting a lawful search incident to arrest must generally obtain a warrant before searching information stored on a cell phone. This ruling has the following implications. First, the notion that officer safety and the preservation of evidence are the reasons for allowing a warrantless search of the person of the arrestee, as well as a search of the scene of the arrest. Secondly, warrant requirements can protect privacy stored...

76 FR 31941 - Atlantic Coastal Fisheries Cooperative Management Act Provisions; Horseshoe Crabs; Application...

Science.gov (United States)

2011-06-02

.... SUMMARY: The Acting Director, Office of Sustainable Fisheries, has made a preliminary determination that... Court House, NJ, contains all the required information and warrants further consideration. The proposed... should be sent to Emily Menashes, Acting Director, Office of Sustainable Fisheries, NMFS, 1315 East-West...

Predictors for the development of referral-warranted retinopathy of prematurity in the telemedicine approaches to evaluating acute-phase retinopathy of prematurity (e-ROP) study.

Science.gov (United States)

Ying, Gui-Shuang; Quinn, Graham E; Wade, Kelly C; Repka, Michael X; Baumritter, Agnieshka; Daniel, Ebenezer

2015-03-01

Detection of treatment-requiring retinopathy of prematurity (ROP) involves serial eye examinations. An ROP prediction model using predictive factors could identify high-risk infants and reduce required eye examinations. To determine predictive factors for the development of referral-warranted (RW) ROP. This multicenter observational cohort study included secondary analysis of data from the Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity Study. Infants included in the study had a birth weight (BW) of less than 1251 g. Serial ROP examinations of premature infants who had 2 or more ROP examinations. Incidence of RW-ROP (defined as the presence of plus disease, zone I ROP, or ROP stage 3 or greater in either eye) and associations with predictive factors. Among 979 infants without RW-ROP at first study-related eye examination (median postmenstrual age, 33 weeks; range, 29-40 weeks) who underwent at least 2 eye examinations, 149 (15.2%) developed RW-ROP. In a multivariate model, significant predictors for RW-ROP were male sex (odds ratio [OR], 1.80; 95% CI, 1.13-2.86 vs female), nonblack race (OR, 2.76; 95% CI, 1.50-5.08 for white vs black race and OR, 4.81; 95% CI, 2.19-10.6 for other vs black race), low BW (OR, 5.16; 95% CI, 1.12-7.20 for ≤500 g vs >1100 g), younger gestational age (OR, 9.79; 95% CI, 3.49-27.5 for ≤24 weeks vs ≥28 weeks), number of quadrants with preplus disease (OR, 7.12; 95% CI, 2.53-20.1 for 1-2 quadrants and OR, 18.4; 95% CI, 4.28-79.4 for 3-4 quadrants vs no preplus disease), stage 2 ROP (OR, 4.13; 95% CI, 2.13-8.00 vs no ROP), the presence of retinal hemorrhage (OR, 4.36; 95% CI, 1.57-12.1 vs absence), the need for respiratory support (OR, 4.99; 95% CI, 1.89-13.2 for the need for controlled mechanical ventilator; OR, 11.0; 95% CI, 2.26-53.8 for the need for high-frequency oscillatory ventilation vs no respiratory support), and slow weight gain (OR, 2.44; 95% CI, 1.22-4.89 for weight gain ≤12 g/d vs >18 g

77 FR 45247 - Implementation of Statute of Limitations Provisions for Office Disciplinary Proceedings

Science.gov (United States)

2012-07-31

... warranted, it is necessary * * * to get the practitioner's side of the story first.'' The comment... Technology Transfer and Advancement Act: The requirements of section 12(d) of the National Technology...

Three Pervasive Presuppositions about Human Life and Ethics Strongly Warrant Analysis

NARCIS (Netherlands)

Miller, Lantz E.

2017-01-01

Common philosophical discussions concerning the ethics of human interaction with the biosphere and universe have been significantly informed by certain presuppositions: (1) nature is conquerable; (2) human cultural and social (contrasted with moral) progress is somewhat like a thing, beyond human

Hepatic pseudoaneurysm after traumatic liver injury; is CT follow-up warranted?

DEFF Research Database (Denmark)

Østerballe, Lene; Helgstrand, Frederik; Axelsen, Thomas

2014-01-01

INTRODUCTION: Hepatic pseudoaneurysm (HPA) is a rare complication after liver trauma, yet it is potentially fatal, as it can lead to sudden severe haemorrhage. The risk of developing posttraumatic HPA is one of the arguments for performing follow-up CT of patients with liver injuries. The aim...... no treatment failures. There was no correlation between the severity of the liver injury and development of HPA. 5 out of 7 patients were asymptomatic and would have been discharged without treatment if the protocol did not include a default follow-up CT. CONCLUSIONS: In conclusion, this study shows that HPA...

An Evaluation of the Limited Contract Warrant Experiment at March AFB.

Science.gov (United States)

1986-09-01

than $1,000, and these account for only 4.5% of the total dollars expended (23). Statistics for the entire Air Force reflect a similar situation. In FY...sent with the workbook for the person administering the course.(2 1:1) The subjects covered in the coursebook are: Introduction to Defense Small...7 course as statistics are maintained by each of the 112 chapters separately. (56) There are some private consultants who provide training in this

Do ultra-orphan medicinal products warrant ultra-high prices? A review

Directory of Open Access Journals (Sweden)

Picavet E

2013-06-01

Full Text Available Eline Picavet,1 David Cassiman,2 Steven Simoens1 1Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; 2Department of Hepatology, University Hospital Leuven, Leuven, Belgium Abstract: Ultra-orphan medicinal products (ultra-OMPs are intended for the treatment, prevention, or diagnosis of ultra-rare diseases, ie, life-threatening or chronically debilitating diseases that affect less than one per 50,000 individuals. Recently, high prices for ultra-OMPs have given rise to debate on the sustainability and justification of these prices. The aim of this article is to review the international scientific literature on the pricing of ultra-OMPs and to provide an overview of the current knowledge on the drivers of ultra-OMP pricing. The pricing process of ultra-OMPs is a complex and nontransparent issue. Evidence in the literature seems to indicate that ultra-OMPs are priced according to rarity and what the manufacturer believes the market will bear. Additionally, there appears to be a trend between the price of an ultra-OMP and the number of available alternatives. Patients, third-party payers, and pharmaceutical companies could benefit from more transparent pricing strategies. With a view to containing health care costs, it is likely that cost-sharing strategies, such as performance-based risk sharing arrangements, will become increasingly more important. However, it is vital that any measures for price control are consistent with the intended goals of the incentives to promote the development of new OMPs. Ideally, a balance must be struck between attaining affordable prices for ultra-OMPs and securing a realistic return on investment for the pharmaceutical industry. Keywords: ultra-orphan medicinal product, ultra-rare disease, pricing

Clozapine-Induced Myocarditis: Is Mandatory Monitoring Warranted for Its Early Recognition?

Directory of Open Access Journals (Sweden)

T. A. Munshi

2014-01-01

Full Text Available Clozapine is an atypical antipsychotic used for treatment resistant schizophrenia. Its potential to induce agranulocytosis is well known but it can also cause myocarditis. Clozapine is the only antipsychotic known to induce this side effect, typically early in the treatment, and literature is scarce on this condition. We are presenting a case report of a 21-year-old schizophrenic male who developed myocarditis within 3 weeks of starting on clozapine for his treatment resistant psychosis. We then aim to review some of the available literature and raise awareness among physicians as this condition can potentially be fatal if not detected early.

Warranting Failure: The "System" that Breeds Poverty and Starves Public Schools

Science.gov (United States)

Alexander, Kern; Salmon, Richard G.

2007-01-01

The inscription on the internal pedestal of the Statue of Liberty proclaiming "Give me your tired, your poor, your huddled masses" today is an ideal of another age. Compared with those of other developing countries, U.S. poverty rates are extraordinarily high, as are the odds of remaining in poverty intergenerationally. No longer do…

37 CFR 10.39 - Acceptance of employment.

Science.gov (United States)

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Acceptance of employment. 10... Office Code of Professional Responsibility § 10.39 Acceptance of employment. A practitioner shall not... in litigation or any proceeding before the Office that is not warranted under existing law, unless it...

78 FR 9698 - Agency Forms Undergoing Paperwork Reduction Act Review

Science.gov (United States)

2013-02-11

... standard in healthcare, this has been limited in laboratory medicine. No single-evidence-based model for... United States and the volume of laboratory tests available certainly warrant such a model. The Laboratory... Integrity (OSI), Office of the Associate Director for Science (OADS), Office of the Director, Centers for...

Office bladder distention with Electromotive Drug Administration (EMDA is equivalent to distention under General Anesthesia (GA

Directory of Open Access Journals (Sweden)

Azevedo Kathryn J

2005-11-01

Full Text Available Abstract Background Bladder distention is commonly used in diagnosis and treatment of interstitial cystitis (IC. Traditionally performed in the operating room under general or spinal anesthesia (GA, it is expensive and associated with short term morbidity. Office bladder distention using electromotive drug administration (EMDA has been suggested as an alternative that is well tolerated by patients. We report the first comparative findings of patients undergoing both office distention with EMDA and distention in the operating room (OR with GA. Methods This retrospective chart review identified 11 patients participating in two protocols of EMDA bladder distention who also underwent bladder distention under GA either prior to or after the EMDA procedure. Results The median absolute difference in bladder capacity between GA and EMDA was only 25 cc; the median percent difference was 5%. Cystoscopic findings, while not prospectively compiled, appear to have been similar. Conclusion This study represents the first comparison between distention with EMDA versus GA and confirms the technical feasibility of performing bladder distention in an office setting. The distention capacity achieved in the office was nearly identical to that in the OR and the cystoscopic findings very similar. Further investigation into the comparative morbidity, cost, and other outcome measures is warranted to define the ultimate role of EMDA bladder distention in the clinical evaluation and care of patients with IC.

2013 CENTER FOR ARMY LEADERSHIP ANNUAL SURVEY OF ARMY LEADERSHIP (CASAL): MAIN FINDINGS

Science.gov (United States)

2014-04-30

The Center for Army Profession and Ethic (CAPE) has fielded education and training materials (including doctrine, pamphlets , videos, brochures , and...Army Pamphlet (DA PAM) 600-3, Commissioned Officer Development and Career Management, states that a goal of warrant officer training and education... Pamphlet 600-25, U.S. Army noncommissioned officer professional development and career management. Washington, D.C.: Headquarters, Department of the Army

Chief, National Guard Bureau - Leadership - The National Guard

Science.gov (United States)

the ARNG Deputy Director of the ARNG Chief of Staff of the ARNG Command Chief Warrant Officer of the the ANG Chief of Staff of the ARNG CCW Officer of the ARNG CSM of the ARNG Bottom Links National Guard Civic Leader's Guide ARNG Vision 2020 Posture Statement Strategic Direction CNGB ARNG Financial Report

The Office of Science Data-Management Challenge

Energy Technology Data Exchange (ETDEWEB)

Mount, Richard P.; /SLAC

2005-10-10

Science--like business, national security, and even everyday life--is becoming more and more data intensive. In some sciences the data-management challenge already exceeds the compute-power challenge in its needed resources. Leadership in applying computing to science will necessarily require both world-class computing and world-class data management. The Office of Science program needs a leadership-class capability in scientific data management. Currently two-thirds of Office of Science research and development in data management is left to the individual scientific programs. About $18M/year is spent by the programs on data-management research and development targeted at their most urgent needs. This is to be compared with the $9M/year spent on data management by DOE computer science. This highly mission-directed approach has been effective, but only in meeting just the highest-priority needs of individual programs. A coherent, leadership-class, program of data management is clearly warranted by the scale and nature of the Office of Science programs. More directly, much of the Office of Science portfolio is in desperate need of such a program; without it, data management could easily become the primary bottleneck to scientific progress within the next five years. When grouped into simulation-intensive science, experiment/observation-intensive science, and information-intensive science, the Office of Science programs show striking commonalities in their data-management needs. Not just research and development but also packaging and hardening as well as maintenance and support are required. Meeting these needs is a medium- to long-term effort requiring a well-planned program of evolving investment. We propose an Office of Science Data-Management Program at an initial scale of $32M/year of new funding. The program should be managed by a Director charged with creating and maintaining a forward-looking approach to multiscience data-management challenges. The program

48 CFR 801.690-1 - Definitions.

Science.gov (United States)

2010-10-01

... purchasing agents; contracting officers warranted above the micro-purchase threshold; program and project... statement includes information on experience, education, training, and pertinent contracting authority... experience leading to the fulfillment of core competencies in acquisition-related disciplines. Selection...

46 CFR 501.5 - Functions of the organizational components of the Federal Maritime Commission.

Science.gov (United States)

2010-10-01

...) The Office initiates recommendations, collaborating with other elements of the Commission as warranted... Assistant Managing Director initiates recommendations, collaborating with other elements of the Commission...) Conducts investigations leading to enforcement action, advises the Commission of evolving competitive...

32 CFR 935.125 - Citation in place of arrest.

Science.gov (United States)

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Citation in place of arrest. 935.125 Section 935... INSULAR REGULATIONS WAKE ISLAND CODE Peace Officers § 935.125 Citation in place of arrest. In any case in which a peace officer may make an arrest without a warrant, he may issue and serve a citation if he...

32 CFR Appendix D to Part 275 - Obtaining Access By Search Warrant

Science.gov (United States)

2010-07-01

... (CONTINUED) MISCELLANEOUS OBTAINING INFORMATION FROM FINANCIAL INSTITUTIONS: RIGHT TO FINANCIAL PRIVACY ACT... of Criminal Procedure. B. Unless a delay of notice has been obtained under provisions of Appendix H... following purpose: [state purpose]. You may have rights under the Right to Financial Privacy Act of 1978.” C...

Isolated metastasis of colon cancer to the scapula: is surgical resection warranted?

Directory of Open Access Journals (Sweden)

Onesti Jill K

2011-10-01

Full Text Available Abstract Background Distant metastases from colon cancer spread most frequently to the liver and the lung. Risk factors include positive lymph nodes and high grade tumors. Isolated metastases to the appendicular skeleton are very rare, particularly in the absence of identifiable risk factors. Case report The patient was a 55 year old male with no previous personal or family history of colon cancer. Routine screening revealed a sigmoid adenocarcinoma. He underwent resection with primary anastomosis and was found to have Stage IIA colon cancer. He declined chemotherapy as part of a clinical trial, and eight months later was found to have an isolated metastasis in his right scapula. This was treated medically, but grew to 12 × 15 cm. The patient underwent a curative forequarter amputation and is now more than four years from his original colon surgery. Discussion Stage IIA colon cancers are associated with a high five year survival rate, and chemotherapy is not automatically given. If metastases occur, they are likely to arise from local recurrence or follow lymphatic dissemination to the liver or lungs. Isolated skeletal metastases are quite rare and are usually confined to the axial skeleton. To our knowledge, this is the first reported case of an isolated scapular metastasis in a patient with node negative disease. The decision to treat the recurrence with radiation and chemotherapy did not reduce the tumor, and a forequarter amputation was eventually required. Conclusion This case highlights the importance of adequately analyzing the stage of colon cancer and offering appropriate treatment. Equally important is the early involvement of a surgeon in discussing the timing of the treatment for recurrence. Perhaps if the patient had received chemotherapy or earlier resection, he could have been spared the forequarter amputation. The physician must also be aware of the remote possibility of an unusual presentation of metastasis in order to pursue timely work up.

Does prospect theory warrant a paradigm shift in the economics of risk?

Directory of Open Access Journals (Sweden)

PL Mohapi

2014-07-01

Full Text Available This paper assesses whether a paradigm shift should be made from expected utility framework to prospect theory framework – in the economics of choice under risk. A brief overview of the subject is outlined, starting with expected utility theory and noting its descriptive limitations. Proposed theories to make up for these limitations is also provided. Prospect theory emerged as the most serious challenger to expected utility theory. A review of some descriptive predictions of prospect theory, suggests that there is no scientific reason why expected utility should not be ousted from dominance by prospect theory. The shift to prospect theory however is not without costs. Conceptual complexities and non-universality of application associated with prospect theory should be embraced with the shift while not entirely abandoning expected utility theory.

Limitations of metformin use in patients with kidney disease: are they warranted?

Science.gov (United States)

Vasisht, K P; Chen, S-C; Peng, Y; Bakris, G L

2010-12-01

To show that metformin, one of the most widely used agents, is contraindicated in patients with diabetes having chronic kidney disease (CKD) (i.e. serum creatinine >1.5 mg/dl) secondary to fear of lactic acidosis. The overall incidence of lactic acidosis is estimated at an upper limit of eight cases per 100 000 patient-years. We evaluated metformin use in two cohorts, one from the University of Chicago Diabetes Center and the other from National Health and Nutrition Examination Survey (NHANES) 1999-2006. Estimated glomerular filtration rate (eGFR) was calculated using the re-expressed Modification of Diet in Renal Disease (MDRD) Study equation and compared to serum creatinine. We hypothesized that metformin is used in patients with undetected advanced CKD (i.e. serum creatinine is ≥1.5 mg/dl). A chi-squared test was used to compare per cent differences of metformin use across demographic variables and eGFR in the NHANES cohort. At the University of Chicago Diabetes Center, 36 of 234 (15.3%) patients with an eGFR of metformin. Data from NHANES, age >18 years and eGFR metformin. We conclude that metformin utilization occurs with a higher frequency than predicted by serum creatinine in people with eGFR <60 ml/min/1.73 m(2) . Given the very low incidence of lactic acidosis, the recommendation should be changed to reflect eGFR cut-off values rather than serum creatinine. © 2010 Blackwell Publishing Ltd.

Habits of cell phone usage and sperm quality - does it warrant attention?

Science.gov (United States)

Zilberlicht, Ariel; Wiener-Megnazi, Zofnat; Sheinfeld, Yulia; Grach, Bronislava; Lahav-Baratz, Shirly; Dirnfeld, Martha

2015-09-01

Male infertility constitutes 30-40% of all infertility cases. Some studies have shown a continuous decline in semen quality since the beginning of the 20th century. One postulated contributing factor is radio frequency electromagnetic radiation emitted from cell phones. This study investigates an association between characteristics of cell phone usage and semen quality. Questionnaires accessing demographic data and characteristics of cell phone usage were completed by 106 men referred for semen analysis. Results were analysed according to WHO 2010 criteria. Talking for ≥1 h/day and during device charging were associated with higher rates of abnormal semen concentration (60.9% versus 35.7%, P cell phone usage may bear adverse effects on sperm concentration. Investigation using large-scale studies is thus needed. Copyright © 2015 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Life cycle analysis of organic tandem solar cells: When are they warranted?

DEFF Research Database (Denmark)

Espinosa Martinez, Nieves; Krebs, Frederik C

2014-01-01

in their making when compared with the single junction solar cell has to be justified and compensated by a higher efficiency. A central question to ask is how much energy you need to invest in a system in order for it to produce energy and return the investment at least once and preferably a number of times....... As an initial investigation into the potential viability of the tandem or multi-junction approach we have engaged in a detailed analysis based on the manufacturing energy for each step within the tandem module supply chain for full ambient processing of thin flexible polymer tandem solar cells prepared entirely...

Transcatheter Arterial Embolization for Upper Gastrointestinal Nonvariceal Hemorrhage: Is Empiric Embolization Warranted?

Energy Technology Data Exchange (ETDEWEB)

Arrayeh, Elnasif; Fidelman, Nicholas, E-mail: nicholas.fidelman@ucsf.edu; Gordon, Roy L.; LaBerge, Jeanne M.; Kerlan, Robert K. [University of California San Francisco, Department of Radiology (United States); Klimov, Alexander; Bloom, Allan I. [Hadassah Hospital, Department of Radiology (Israel)

2012-12-15

Purpose: To determine whether transcatheter arterial embolization performed in the setting of active gastric or duodenal nonvariceal hemorrhage is efficacious when the bleeding source cannot be identified angiographically. Methods: Records of 115 adult patients who underwent visceral angiography for endoscopically documented gastric (50 patients) or duodenal (65 patients) nonvariceal hemorrhage were retrospectively reviewed. Patients were subdivided into three groups according to whether angiographic evidence of arterial hemorrhage was present and whether embolization was performed (group 1 = no abnormality, no embolization; group 2 = no abnormality, embolization performed [empiric embolization]; and group 3 = abnormality present, embolization performed). Thirty-day rates and duration of primary hemostasis and survival were compared.ResultsFor patients with gastric sources of hemorrhage, the rate of primary hemostasis at 30 days after embolization was greater when embolization was performed in the setting of a documented angiographic abnormality than when empiric embolization was performed (67% vs. 42%). The rate of primary hemostasis at 30 days after angiography was greater for patients with duodenal bleeding who either underwent empiric embolization (60%) or embolization in the setting of angiographically documented arterial hemorrhage (58%) compared with patients who only underwent diagnostic angiogram (33%). Patients with duodenal hemorrhage who underwent embolization were less likely to require additional invasive procedures to control rebleeding (p = 0.006). Conclusion: Empiric arterial embolization may be advantageous in patients with a duodenal source of hemorrhage but not in patients with gastric hemorrhage.

28 CFR 2.47 - Warrant placed as a detainer and dispositional review.

Science.gov (United States)

2010-07-01

... notified of his right to request counsel under the provisions of § 2.48(b) to assist him in completing this... original sentence is not interrupted by a new conviction (e.g., YCA; NARA; Mexican or Canadian treaty cases...

Focal thyroid incidentalomas identified with whole-body FDG-PET warrant further investigation.

LENUS (Irish Health Repository)

Prichard, R S

2012-02-01

Fluorodeoxyglucose (FDG) whole body positron emission computed tomography (PET-CT) detects clinically occult malignancy. The aim of this study was to assess the prevalence and significance of focal thyroid 18F - fluorodeoxyglucose uptake. A retrospective review of all patients who had FDG PET-CT examinations, in a single tertiary referral centre was performed. PET scan findings and the final pathological diagnosis were collated. 2105 scans were reviewed. Focal uptake was identified in 35 (1.66%) patients. Final surgical histology was available on eight patients, which confirmed papillary carcinoma in four (20%) patients and lymphoma and metastatic disease in two patients respectively. This gave an overall malignancy rate in focal thyroid uptake of at least 33%. Thyroid incidentalomas occurred with a frequency of 2.13%, with an associated malignancy rate of at least 33% in focal thyroid uptake. The high malignancy rate associated with focal thyroid uptake mandates further investigation in medically fit patients.

Dewey's Epistemology: An Argument for Warranted Assertions, Knowing, and Meaningful Classroom Practice

Science.gov (United States)

Boyles, Deron R.

2006-01-01

In an effort to navigate the treacherous path between professionalism and social relevancy, this essay takes up an area of professional philosophy--epistemology--with the intention of reclaiming the integrative role John Dewey held for philosophy and classroom practice. Deron Boyles asserts that epistemology can and should represent an area of…

75 FR 66165 - Information Collection Activities: Proposed Collection; Comment Request

Science.gov (United States)

2010-10-27

... additional information should be collected to further the aims of government transparency. DATES: Comments... OFFICE OF MANAGEMENT AND BUDGET Information Collection Activities: Proposed Collection; Comment... are warranted. We are particularly interested in comments on whether the information collected in the...

76 FR 62433 - Delegation of Authority to the Office of Disaster Management and National Security

Science.gov (United States)

2011-10-07

... and requirements for test, training, and exercises under the Presidential Policy Directive 8: National Preparedness (2011), the National Preparedness Goal, and the National Exercise Plan, including required... Secretary, Deputy Secretary, and their immediate families, as warranted, including authorities set forth in...

14 CFR 271.8 - Rate period.

Science.gov (United States)

2010-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS GUIDELINES FOR SUBSIDIZING AIR CARRIERS PROVIDING ESSENTIAL AIR TRANSPORTATION § 271.8 Rate period... place essential air service level; or (5) The uncertainties of the market or other circumstances warrant...

75 FR 28809 - Notice of Request for Public Comment

Science.gov (United States)

2010-05-24

... use of genetic technologies and, as warranted, to provide advice on these issues. For more information... Services (HHS) on genetics education and training of health care professionals, public health providers... 301-496- 9839. FOR FURTHER INFORMATION CONTACT: Kathryn Camp, NIH Office of Biotechnology Activities...

48 CFR 2011.104-70 - NRC Clauses.

Science.gov (United States)

2010-10-01

... ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Delivery or Performance Schedules-Contract Clauses 2011.104-70...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable cost reimbursement solicitations and contracts when detailed assessment of costs is warranted and a...

4 CFR 21.14 - Request for reconsideration.

Science.gov (United States)

2010-01-01

... GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES BID PROTEST REGULATIONS § 21.14 Request for... reconsideration of a bid protest decision. GAO will not consider a request for reconsideration that does not... deemed warranted, specifying any errors of law made or information not previously considered. (b) A...

East Europe Report, Political, Sociological and Military Affairs, No. 2219

Science.gov (United States)

1983-10-24

takes place in training booths and classrooms. On the way to warrant officer one must take sociology, Russian, basic construction, materials...polemics. I admit that I like this much more than the obligatory hearty kiss on both cheeks along with, of course, the assumption that polemicists have

Regional Controller | IDRC - International Development Research ...

International Development Research Centre (IDRC) Digital Library (Canada)

Identifies, assesses and manages financial and administrative risks together with officers responsible for projects situated in the region by conducting recipient institutional assessments at key points in the project life-cycle, by giving advice to recipients and, where warranted, by organizing training for recipients in the area of ...

27 CFR 71.72 - Before citation.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Before citation. 71.72... Procedure Surrender of Permit § 71.72 Before citation. If a respondent surrenders the permit before citation... appropriate TTB officer, warrants citation for suspension, revocation or annulment, the surrender shall be...

75 FR 36638 - Agency Information Collection Activities; Proposed Collection; Comment Request; Requirements for...

Science.gov (United States)

2010-06-28

... manner to warrant a recall, the required records can be used by the manufacturer or importer and by the Commission to identify those persons and firms who should be notified of the recall. The Commission will... Statistics, Total Compensation, All workers, goods-producing industries, Sales and office, September 2009...

28 CFR 2.48 - Revocation: Preliminary interview.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Revocation: Preliminary interview. 2.48....48 Revocation: Preliminary interview. (a) Interviewing officer. A parolee who is retaken on a warrant issued by a Commissioner shall be given a preliminary interview by an official designated by the Regional...

48 CFR 1313.201 - General.

Science.gov (United States)

2010-10-01

... 1313.201 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CONTRACTING METHODS AND CONTRACT... General. DOC employees, other than warranted contracting officers, must be delegated micro-purchase authority by the designee set forth in CAM 1301.70 according to FAR 1.603-3(b), and must be trained pursuant...

Radiotherapy for esthesioneuroblastoma: is elective nodal irradiation warranted in the multimodality treatment approach?

Science.gov (United States)

Noh, O Kyu; Lee, Sang-wook; Yoon, Sang Min; Kim, Sung Bae; Kim, Sang Yoon; Kim, Chang Jin; Jo, Kyung Ja; Choi, Eun Kyung; Song, Si Yeol; Kim, Jong Hoon; Ahn, Seung Do

2011-02-01

The role of elective nodal irradiation (ENI) in radiotherapy for esthesioneuroblastoma (ENB) has not been clearly defined. We analyzed treatment outcomes of patients with ENB and the frequency of cervical nodal failure in the absence of ENI. Between August 1996 and December 2007, we consulted with 19 patients with ENB regarding radiotherapy. Initial treatment consisted of surgery alone in 2 patients; surgery and postoperative radiotherapy in 4; surgery and adjuvant chemotherapy in 1; surgery, postoperative radiotherapy, and chemotherapy in 3; and chemotherapy followed by radiotherapy or concurrent chemoradiotherapy in 5. Five patients did not receive planned radiotherapy because of disease progression. Including 2 patients who received salvage radiotherapy, 14 patients were treated with radiotherapy. Elective nodal irradiation was performed in 4 patients with high-risk factors, including 3 with cervical lymph node metastasis at presentation. Fourteen patients were analyzable, with a median follow-up of 27 months (range, 7-64 months). The overall 3-year survival rate was 73.4%. Local failure occurred in 3 patients (21.4%), regional cervical failure in 3 (21.4%), and distant failure in 2 (14.3%). No cervical nodal failure occurred in patients treated with combined systemic chemotherapy regardless of ENI. Three cervical failures occurred in the 4 patients treated with ENI or neck dissection (75%), none of whom received systemic chemotherapy. ENI during radiotherapy for ENB seems to play a limited role in preventing cervical nodal failure. Omitting ENI may be an option if patients are treated with a combination of radiotherapy and chemotherapy. Copyright © 2011 Elsevier Inc. All rights reserved.

Expeditionary Forensic Support to Joint Force Commanders: What Changes or Considerations are Warranted?

Science.gov (United States)

2012-04-10

builders . Human Intelligence (HUMINT) and Signals Intelligence (SIGINT) could then also be prioritized and employed accordingly for optimal 8...responsibility for digital and multimedia forensics, and DIA responsibility for forensic intelligence activities and programs.31 The Army is also currently...aligning functional oversight of Forensics, Biometrics, Law Enforcement, Detainee Operations, and Physical Security 11 under one overarching

Detecting and developing youth athlete potential: different strokes for different folks are warranted.

Science.gov (United States)

Suppiah, Haresh T; Low, Chee Yong; Chia, Michael

2015-07-01

Sport talent identification and development (TI and TD) in youth continues to attract strong interest among coaches, sport scientists and sport administrators. TI for sport in youth with the anticipation of future elite level sport achievement is both an art and a science, and is strongly influenced by within athlete and extraneous-to-athlete factors (ecosystem of support or the lack of). The returns from investment on current TI and TD models of sport in youth are subpar in that few continue in the sport to achieve podium positions at the elite sport level in adulthood. Why, where and how one succeeds in sport, and what that success means to the athlete and stakeholders are dependent on the culture and context of the country. We advocate harnessing the power of sport to help in youth development, to be holistic in its nurturance, to allow for individual idiosyncratic expressions of the athletes, to provide for talent transfer across sport, and to facilitate key stakeholders to 'join' hands to work for the common interest and understanding for as many youth and adults so as to provide them with opportunities through support and coaching to compete at the different levels of competition in sport. Governments, policy makers and administrators of sport must decide, within their specific circumstances, if TI and TD in sport in youth is serving a meaningful purpose and is a viable return on investment; in short, is it mission possible or is it… a quest for the Holy Grail for a podium finish in elite level sport competition? Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Patient attributes warranting consideration in clinical practice guidelines, health workforce planning and policy

Directory of Open Access Journals (Sweden)

Segal Leonie

2011-09-01

Full Text Available Abstract Background In order for clinical practice guidelines (CPGs to meet their broad objective of enhancing the quality of care and supporting improved patient outcomes, they must address the needs of diverse patient populations. We set out to explore the patient attributes that are likely to demand a unique approach to the management of chronic disease, and which are crucial if evidence or services planning is to reflect clinic populations. These were incorporated into a new conceptual framework; using diabetes mellitus as an exemplar. Methods The patient attributes that informed the framework were identified from CPGs, the diabetes literature, an expert academic panel, and two cross-disciplinary panels; and agreed upon using a modified nominal group technique. Results Full consensus was reached on twenty-four attributes. These factors fell into one of three themes: (1 type/stage of disease, (2 morbid events, and (3 factors impacting on capacity to self-care. These three themes were incorporated in a convenient way in the workforce evidence-based (WEB model. Conclusions While biomedical factors are frequently recognised in published clinical practice guidelines, little attention is given to attributes influencing a person's capacity to self-care. Paying explicit attention to predictable threats to effective self-care in clinical practice guidelines, by drawing on the WEB model, may assist in refinements that would address observed disparities in health outcomes across socio-economic groups. The WEB model also provides a framework to inform clinical training, and health services and workforce planning and research; including the assessment of healthcare needs, and the allocation of healthcare resources.

Radiotherapy for Esthesioneuroblastoma: Is Elective Nodal Irradiation Warranted in the Multimodality Treatment Approach?

International Nuclear Information System (INIS)

Noh, O Kyu; Lee, Sang-wook; Yoon, Sang Min; Kim, Sung Bae; Kim, Sang Yoon; Kim, Chang Jin; Jo, Kyung Ja; Choi, Eun Kyung; Song, Si Yeol; Kim, Jong Hoon; Ahn, Seung Do

2011-01-01

Purpose: The role of elective nodal irradiation (ENI) in radiotherapy for esthesioneuroblastoma (ENB) has not been clearly defined. We analyzed treatment outcomes of patients with ENB and the frequency of cervical nodal failure in the absence of ENI. Methods and Materials: Between August 1996 and December 2007, we consulted with 19 patients with ENB regarding radiotherapy. Initial treatment consisted of surgery alone in 2 patients; surgery and postoperative radiotherapy in 4; surgery and adjuvant chemotherapy in 1; surgery, postoperative radiotherapy, and chemotherapy in 3; and chemotherapy followed by radiotherapy or concurrent chemoradiotherapy in 5. Five patients did not receive planned radiotherapy because of disease progression. Including 2 patients who received salvage radiotherapy, 14 patients were treated with radiotherapy. Elective nodal irradiation was performed in 4 patients with high-risk factors, including 3 with cervical lymph node metastasis at presentation. Results: Fourteen patients were analyzable, with a median follow-up of 27 months (range, 7-64 months). The overall 3-year survival rate was 73.4%. Local failure occurred in 3 patients (21.4%), regional cervical failure in 3 (21.4%), and distant failure in 2 (14.3%). No cervical nodal failure occurred in patients treated with combined systemic chemotherapy regardless of ENI. Three cervical failures occurred in the 4 patients treated with ENI or neck dissection (75%), none of whom received systemic chemotherapy. Conclusions: ENI during radiotherapy for ENB seems to play a limited role in preventing cervical nodal failure. Omitting ENI may be an option if patients are treated with a combination of radiotherapy and chemotherapy.

75 FR 59234 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

Science.gov (United States)

2010-09-27

... 1508 fail to comply in a manner to warrant a recall, the required records can be used by the... the recall. The Commission will consider all comments received in response to this notice before...) multiplied by a cost of $27.78 per hour (Bureau of Labor Statistics, Total Compensation, All workers, goods...

CHANGES IN FLIGHT TRAINEE PERFORMANCE FOLLOWING SYNTHETIC HELICOPTER FLIGHT TRAINING.

Science.gov (United States)

CARO, PAUL W., JR.; ISLEY, ROBERT N.

A STUDY WAS CONDUCTED AT THE U.S. ARMY PRIMARY HELICOPTER SCHOOL, FORT WOLTERS, TEXAS, TO DETERMINE WHETHER THE USE OF A HELICOPTER TRAINING DEVICE WOULD IMPROVE STUDENT PERFORMANCE DURING SUBSEQUENT HELICOPTER CONTACT FLIGHT TRAINING. SUBJECTS WERE TWO EXPERIMENTAL GROUPS AND TWO CONTROL GROUPS OF WARRANT OFFICER CANDIDATES ENROLLED FOR A…

42 CFR 31.2 - Persons entitled to treatment.

Science.gov (United States)

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Persons entitled to treatment. 31.2 Section 31.2... Public Health Service § 31.2 Persons entitled to treatment. To the extent and under the circumstances... treatment and hospitalization by the Service: (a) Coast Guard. (1) Commissioned officers, chief warrant...

75 FR 27934 - Qualified Nonpersonal Use Vehicles

Science.gov (United States)

2010-05-19

... law to carry firearms, execute search warrants, and to make arrests (other than merely a citizen's... safety officer vehicles occurring after May 19, 2010. FOR FURTHER INFORMATION CONTACT: Don Parkinson at... final Income Tax Regulations under section 274(i) added by section 2(b) of Public Law 99-44 (May 24...

26 CFR 601.105 - Examination of returns and claims for refund, credit or abatement; determination of correct tax...

Science.gov (United States)

2010-04-01

... technical advice, the National Office shall inform the taxpayer orally or in writing of the material likely... determines that technical advice is not warranted, he will inform the taxpayer in writing that he proposes to... relating to the issue for which technical advice has been sought, including taxpayer's written request and...

22 CFR 9a.4 - Classification.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Classification. 9a.4 Section 9a.4 Foreign... ENERGY PROGRAMS; RELATED MATERIAL § 9a.4 Classification. (a) Section 1 of E.O. 11932, August 4, 1976.... If the officer determines that the information or material warrants classification, he shall assign...

31 CFR 1.26 - Procedures for notification and access to records pertaining to individuals-format and fees for...

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Procedures for notification and... Money and Finance: Treasury Office of the Secretary of the Treasury DISCLOSURE OF RECORDS Privacy Act... whether it continues to warrant classification under the criteria of sections 1 and 5 (B), (C), (D) and (E...

Concept, Content, Construction, and Contingencies: Getting the Horse before the PowerPoint Cart

Science.gov (United States)

DuFrene, Debbie D.; Lehman, Carol M.

2004-01-01

The phrase "death by PowerPoint" was not born in the offices of Microsoft's competitors; it came straight from the hearts of victimized meeting attendees. Microsoft estimates that at least 30 million PowerPoint presentations are made daily, with many rightfully warranting death verdict assessment. Death sentences often result from a "construction…

75 FR 59233 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

Science.gov (United States)

2010-09-27

... 1509 fail to comply in a manner to warrant a recall, the required records can be used by the... the recall. In the Federal Register of June 28, 2010 (75 FR 36637), the CPSC published a 60-day notice... (16 firms x 5 hours each) multiplied by a cost of $27.78 per hour (Bureau of Labor Statistics, Total...

Search and seizure law; practical advice and interpretation for nuclear protective force persons

Energy Technology Data Exchange (ETDEWEB)

Cadwell, J.J.

1983-07-06

Recent Supreme Court decisions, which interpret the 200-year-old Fourth Amendment of the US Constitution, are used to provide a brief overview of some search and seizure subjects important to management and officers responsible for physical protection of nuclear facilities. The overview is framed in practical terms in order to make the comments applicable to the everyday activity of nuclear-protective-force persons. The Supreme Court has described several exceptions where searches and seizures (arrests) are permitted without a warrant, despite the Fourth Amendment which states that warrants are always required. The seven exceptions briefly discussed are search incidents to a lawful arrest, the automobile-search exception, the suitcase or container exception, the hot-pursuit or emergency exception, the stop-and-frisk exception, the plain-view exception, and consent to be searched.

Search and seizure law; practical advice and interpretation for nuclear protective force persons

International Nuclear Information System (INIS)

Cadwell, J.J.

1983-01-01

Recent Supreme Court decisions, which interpret the 200-year-old Fourth Amendment of the US Constitution, are used to provide a brief overview of some search and seizure subjects important to management and officers responsible for physical protection of nuclear facilities. The overview is framed in practical terms in order to make the comments applicable to the everyday activity of nuclear-protective-force persons. The Supreme Court has described several exceptions where searches and seizures (arrests) are permitted without a warrant, despite the Fourth Amendment which states that warrants are always required. The seven exceptions briefly discussed are search incidents to a lawful arrest, the automobile-search exception, the suitcase or container exception, the hot-pursuit or emergency exception, the stop-and-frisk exception, the plain-view exception, and consent to be searched

SOUTH AFRICAN ARMY RANKS AND INSIGNIA

African Journals Online (AJOL)

the lieutenant-colonel a crown and one star, the major a crown, and the captain and the lieuten- ant respectively three and two stars. The crown was the "Tudor" or "king's" pattern and the star, popularly called a "pip", was based on the Order of the Bath. Warrant officers also wore a crown, those hold- ing senior positions.

Special Staff - Joint Staff - Leadership - The National Guard

Science.gov (United States)

the ARNG Deputy Director of the ARNG Chief of Staff of the ARNG Command Chief Warrant Officer of the Site Maintenance Battle Focused Training Strategy Battle Staff Training Resources News Publications March Today in Guard History Leadership CNGB VCNGB SEA DANG DARNG Joint Staff J-1 J-2 J-3 J-4 J-5 J-6 J

Personal Staff - Joint Staff - The National Guard

Science.gov (United States)

the ARNG Deputy Director of the ARNG Chief of Staff of the ARNG Command Chief Warrant Officer of the Site Maintenance Battle Focused Training Strategy Battle Staff Training Resources News Publications March Today in Guard History Leadership CNGB VCNGB SEA DANG DARNG Joint Staff J-1 J-2 J-3 J-4 J-5 J-6 J

Twenty Years of Brassinosteroids : Steroidal Plant Hormones Warrant Better Crops for the XXI Century

NARCIS (Netherlands)

Khripach, V.; Zhabinskii, V.; Groot, de C.P.G.M.

2000-01-01

The discovery of brassinosteroids (BS) just over 20 years ago opened a new era in studies of bio-regulation in living organisms. Previously, the only known role of steroids as hormones was in animals and fungi; now a steroidal hormone in plants had been added. Progress in brassinosteroid research

Paranormal phenomena in the medical literature sufficient smoke to warrant a search for fire.

Science.gov (United States)

Bobrow, Robert S

2003-06-01

Paranormal phenomena - events that cannot be explained by existing science - are regularly reported in medicine. Surveys have shown that a majority of the population of the United States and Great Britain hold at least one paranormal belief. Information was retrieved by MEDLINE searches using keywords 'paranormal' and 'psychic', and from the author's own collection. Reports are predominantly by physicians, and from peer-reviewed, MEDLINE-indexed literature. This is a representative sample, as there is no database for paranormal medical phenomena. Presented and discussed are: a case of systemic lupus erythematosis ameliorated by witchcraft; an analysis of studies on distant healing; acupuncture, as a bridge between what is now accepted but recently would have been deemed paranormal; a carefully-done study of a psychic; auditory hallucinations informing a patient, correctly, that she had a brain tumor; two nearly-identical lay press reports of self-predicted death; lycanthropy (the delusion of being an animal); the development of Carl Jung's collective unconscious; hypnosis - still questioned despite documented therapeutic benefit, and a well-researched report of a person speaking a foreign language, apparently unlearned (xenoglossy) while hypnotized; and multiple examples of children who spout the details of the life of an unknown, deceased person. The inability of existing paradigms to explain these observations does not negate them; rather, it elucidates a need for more research.

Approach to the Pediatric Patient with Graves’ Disease: When Is Definitive Therapy Warranted?

Science.gov (United States)

2011-03-01

in children Signs Symptoms Goiter Hyperactivity Tachycardia Palpitations Weight loss Sleep disturbance Heat intolerance Fatigue Tremor Poor school...service for reeval-uation of Graves’ disease (GD). She had been diag- nosed with hyperthyroidism 3 yr earlier and treated with methimazole (MMI) titrated...to secondhand smoke. On physical examination, the patient had a heart rate of 105 beats per minute, blood pressure of 114/55 mm Hg, weight of 61 kg

Characterization of commercial building appliances. Final report

Energy Technology Data Exchange (ETDEWEB)

Patel, R.F.; Teagan, P.W.; Dieckmann, J.T.

1993-08-01

This study focuses on ``other`` end-uses category. The purpose of this study was to determine the relative importance of energy end-use functions other than HVAC and lighting for commercial buildings, and to identify general avenues and approaches for energy use reduction. Specific energy consuming technologies addressed include non-HVAC and lighting technologies in commercial buildings with significant energy use to warrant detailed analyses. The end-uses include office equipment, refrigeration, water heating, cooking, vending machines, water coolers, laundry equipment and electronics other than office equipment. The building types include offices, retail, restaurants, schools, hospitals, hotels/motels, grocery stores, and warehouses.

Training and Organization of the U.S. Army Reserve Components: A reference Text for Total Force Trainers and a Guide to Other U.S. Military Services, 1988-1989

Science.gov (United States)

1989-06-01

advance of and/or hearing aids . bility. the unit. 7. Conduct premobili- 7. Identify personnel 7. Identify lodging zation briefing, requiring lens inserts...IDENTIFICATION AND ENROLLMENT SYSTEM SWOT - SENIOR WARRANT OFFICER TRAINING TACP - TACTICAL AIR CONTROL PARTY TADSS - TRAINING AIDS , DEVICES, SIMULATIONS, AND...provide a systemic assessment and analysis of factors affecting RC readiness, and to gain VCSA decisions and support on critical systemic issues

10 CFR 1045.17 - Classification levels.

Science.gov (United States)

2010-01-01

...) Top Secret. The Director of Classification shall classify RD information Top Secret if it is vital to... exceptionally grave damage to the national security. Examples of RD information that warrant Top Secret... comprehensive to warrant designation as Top Secret. Examples of RD information that warrant Secret...

Adverse pathology and undetectable ultrasensitive prostate-specific antigen after radical prostatectomy: is adjuvant radiation warranted?

Science.gov (United States)

Simon, Ross M; Howard, Lauren E; Freedland, Stephen J; Aronson, William J; Terris, Martha K; Kane, Christopher J; Amling, Christopher L; Cooperberg, Matthew R; Vidal, Adriana C

2016-06-01

To determine if men with adverse pathology but undetectable ultrasensitive (<0.01 ng/mL) PSA are at high-risk for biochemical recurrence (BCR), or if there is a subset of patients at low-risk for whom the benefit of adjuvant radiation therapy might be limited. We evaluated 411 patients treated with RP from 2001 to 2013 without adjuvant radiation who had an undetectable (<0.01 ng/mL) PSA level after RP but with adverse pathology [positive surgical margins (PSMs), extraprostatic extension (EPE), and/or seminal vesicle invasion (SVI)]. Multivariable Cox regression analyses tested the relationship between pathological characteristics and BCR to identify groups of men at highest risk of early BCR. On multivariable analysis, only pathological Gleason 7 (4 + 3), Gleason ≥8, and SVI independently predicted BCR (P = 0.019, P < 0.001, and P = 0.001, respectively), although on two-way analysis men with Gleason 7 (4 + 3) did not have significantly higher rates of BCR compared with patients with Gleason ≤6 (log-rank, P = 0.074). Men with either Gleason ≥8 (with PSMs or EPE) or SVI (15% of the cohort) defined a high-risk group vs men without these characteristics (3-year BCR risk of 50.4% vs 11.9%, log-rank, P < 0.001). Among men with adverse pathology but an undetectable (<0.01 ng/mL) PSA level after RP, the benefits of adjuvant radiation are probably limited except for men with Gleason 8-10 (with PSMs or EPE) or SVI who are at high-risk of early BCR. © 2015 The Authors BJU International © 2015 BJU International Published by John Wiley & Sons Ltd.

26 CFR 1.1504-4 - Treatment of warrants, options, convertible obligations, and other similar interests.

Science.gov (United States)

2010-04-01

... the option in absolute terms and in relation to the fair market value of the stock or the exercise... the option is subject (e.g., a public offering of the issuing corporation's stock or reaching a... income. It is anticipated that P, S, and T will continue their earnings histories for several more years...

78 FR 20717 - Endangered and Threatened Wildlife and Plants; Proposed Endangered, Threatened, and Not Warranted...

Science.gov (United States)

2013-04-05

...). Although indirect age validation studies for S. lewini are still inconclusive, bomb radiocarbon and calcein... the ESA: Northwest Atlantic and Gulf of Mexico (NW Atlantic & GOM DPS); Central and Southwest Atlantic... States (from New Jersey to Florida) to Brazil, including the Gulf of Mexico and Caribbean Sea. In the...

75 FR 77496 - Endangered and Threatened Species; Proposed Threatened and Not Warranted Status for Subspecies...

Science.gov (United States)

2010-12-10

... concern, related by the common driver of carbon dioxide (CO 2 ) emissions, is the modification of habitat... suggested that ecological influences or sexual selection, and not a geographical feature restricting gene.... The IPCC AR4 used a range of future greenhouse gas (GHG) emissions produced under six ``marker...

A Logistic Regression and Markov Chain Model for the Prediction of Nation-state Violent Conflicts and Transitions

Science.gov (United States)

2016-03-24

current USD) 179 179 164 1990 0 Improved Water Source (% population with access ) 178 175 175 1960 1 Life Expectancy (years) 182 182 1990 2 Military...Microsoft Office visual basic ( VBA ) based consolidated 42 database tool was developed to compile the 39 separate identifying-information and data...conflict remains in conflictP A brief discussion of the accessibility of states within a Markov model is warranted before we proceed further

Hypothyroidism in adults. Levothyroxine if warranted by clinical and laboratory findings, not for simple TSH elevation.

Science.gov (United States)

2015-10-01

Hypothyroidism is a common disorder due to inadequate thyroid hormone secretion. When a patient has signs and symptoms suggestive of hypothyroidism, how is it determined whether thyroid hormone replacement therapy will have a favourable harm-benefit balance? How should treatment be managed? To answer these questions, we conducted a review of the literature using the standard Prescrire methodology. The symptoms of hypothyroidism are due to slow metabolism (constipation, fatigue, sensitivity to cold, weight gain, etc.) and to polysaccharide accumulation in certain tissues, leading to hoarseness, eyelid swelling, etc. A blood TSH concentration of less than 4 or 5 mlU/L rules out peripheral hypothyroidism. TSH levels increase with age. Between 30% and 60% of high TSH levels are not confirmed on a second blood test. In overt hypothyroidism, the TSH level is high and the free T4 (thyroxine) level is low. Most of these patients are symptomatic. So-called subclinical hypothyroidism, which is rarely symptomatic, is characterised by high blood TSH levels and normal free T4 levels. The natural history of hypothyroidism depends on its cause. In chronic autoimmune thyroiditis, the most common form seen in rich countries, hypothyroidism generally worsens over time. However, other situations can lead to transient hypothyroidism that may last several weeks or months. Subclinical hypothyroidism, as the name implies, is usually asymptomatic. The risk of progression to overt hypothyroidism is about 3% to 4% per year overall but increases with the initial TSH level. Treatment guidelines are mainly based on physiological and pharmacological considerations and generally recommend levothyroxine therapy. The adverse effects of levothyroxine are signs of thyrotoxicosis in case of overdose (tachycardia, tremor, sweating, etc.). Even a slight overdose carries a risk of osteoporotic fractures and atrial fibrillation, especially in the elderly. In young adults, levothyroxine is usually started at a dose of about 1.5 microg/kg per day, taken on an empty stomach. Elderly patients and those with coronary artery disease should start at a lower dose: 12.5 to 50 microg per day. Treatment monitoring is based mainly on blood TSH assay. Dose adjustment should only be considered after 6 to 12 weeks, given the long half-life of levothyroxine. Certain drugs, such as iron and calcium, reduce the gastrointestinal absorption of levothyroxine. Enzyme inducers reduce its efficacy. In 2015, there is no robust evidence that levothyroxine therapy has any tangible benefit in patients with subclinical hypothyroidism. Some practice guidelines recommend treatment when the TSH level is above 10 mIU/L, or sometimes trial treatment for a few months for patients with symptoms suggestive of hypothyroidism. In practice, replacement therapy is needed for patients with overt hypothyroidism and a blood TSH concentration above 10 mIU/L. The main challenge is to recognise transient hypothyroidism, which does not require life-long treatment. When the TSH is only slightly elevated, there is a risk of attributing non-specific symptoms to an abnormal laboratory result and prescribing unnecessary treatment. Watchful waiting is an alternative to routine levothyroxine prescription in case of TSH elevation.

An Attitude Survey Analysis of CONUS Air Force Jet Propulsion Technicians Towards the Warranted Tool Program.

Science.gov (United States)

1983-09-01

34 eN #0 R CC "B N "C "w "D C NO" NCC NCO3814 "" NEtV U A" "I"e0 R ""A e H" NO" NO" e" " " o񓼕.91 CC "E3" 34 NC" "B" C"DT NCTM CAN NfDe N[N C3N NBC

Occurrence of DNET and other brain tumors in Noonan syndrome warrants caution with growth hormone therapy.

Science.gov (United States)

McWilliams, Geoffrey D; SantaCruz, Karen; Hart, Blaine; Clericuzio, Carol

2016-01-01

Noonan syndrome (NS) is an autosomal dominant developmental disorder caused by mutations in the RAS-MAPK signaling pathway that is well known for its relationship with oncogenesis. An 8.1-fold increased risk of cancer in Noonan syndrome has been reported, including childhood leukemia and solid tumors. The same study found a patient with a dysembryoplastic neuroepithelial tumor (DNET) and suggested that DNET tumors are associated with NS. Herein we report an 8-year-old boy with genetically confirmed NS and a DNET. Literature review identified eight other reports, supporting the association between NS and DNETs. The review also ascertained 13 non-DNET brain tumors in individuals with NS, bringing to 22 the total number of NS patients with brain tumors. Tumor growth while receiving growth hormone (GH) occurred in our patient and one other patient. It is unknown whether the development or progression of tumors is augmented by GH therapy, however there is concern based on epidemiological, animal and in vitro studies. This issue was addressed in a 2015 Pediatric Endocrine Society report noting there is not enough data available to assess the safety of GH therapy in children with neoplasia-predisposition syndromes. The authors recommend that GH use in children with such disorders, including NS, be undertaken with appropriate surveillance for malignancies. Our case report and literature review underscore the association of NS with CNS tumors, particularly DNET, and call attention to the recommendation that clinicians treating NS patients with GH do so with awareness of the possibility of increased neoplasia risk. © 2015 Wiley Periodicals, Inc.

The Temporal Relationship Between Intrafamilial Violence, Deployment, and Serious Mental Illness in US Army Service Members

Science.gov (United States)

2017-01-01

sexual abuse (995.53), neglect (995.52), emotional abuse (995.51), and unspecified abuse (995.50, 995.59). Children less than 2 years of age with an...The child’s age at the start of the episode was categorized as 0-2 years, 3-5 years, and 6 years or older . Episode characteristics included the...officer/warrant) or maltreatment type ( sexual , physical, or neglect/other). A final model explored whether age of the child modified the linkage results

Is fuel poverty in Ireland a distinct type of deprivation?

OpenAIRE

Watson, Dorothy; Maitre, Bertrand

2014-01-01

In this paper, we draw on the Central Statistics Office SILC data for Ireland to ask whether fuel poverty is a distinctive type of deprivation that warrants a fundamentally different policy response than poverty in general. We examine the overlap between fuel poverty (based on three self-report items) and poverty in general – with a particular emphasis on the national indicator of basic deprivation which is used in the measurement of poverty for policy purposes in Ireland. We examine changes ...

Legal Services: Military Justice

Science.gov (United States)

1999-08-20

Individ- ual File ( CMIF ) and the MPRJ will be destroyed. b. Wholly set aside since 1 September 1979. All DA Forms 2627 of commissioned officers, warrant...routinely be trans- ferred to the restricted fiche. The DA Form 2627 reflecting the original imposition of punishment, if filed in the MPRJ or CMIF , will be...Records of nonjudicial punishment wholly set aside prior to 1 September 1979. Copies of such records filed in the CMIF and the MPRJ will be destroyed. (2

Qualitative assessment of take-home naloxone program participant and law enforcement interactions in British Columbia.

Science.gov (United States)

Deonarine, Andrew; Amlani, Ashraf; Ambrose, Graham; Buxton, Jane A

2016-05-21

The British Columbia take-home naloxone (BCTHN) program has been in operation since 2012 and has resulted in the successful reversal of over 581 opioid overdoses. The study aims to explore BCTHN program participant perspectives about the program, barriers to participants contacting emergency services (calling "911") during an overdose, and perspectives of law enforcement officials on naloxone administration by police officers. Two focus groups and four individual interviews were conducted with BCTHN program participants; interviews with two law enforcement officials were also conducted. Qualitative analysis of all transcripts was performed. Positive themes about the BCTHN program from participants included easy to understand training, correcting misperceptions in the community, and positive interactions with emergency services. Potential barriers to contacting emergency services during an overdose include concerns about being arrested for outstanding warrants or for other illegal activities (such as drug possession) and confiscation of kits. Law enforcement officials noted that warrants were complex situational issues, kits would normally not be confiscated, and admitted arrests for drug possession or other activities may not serve the public good in an overdose situation. Law enforcement officials were concerned about legal liability and jurisdictional/authorization issues if naloxone administration privileges were expanded to police. Program participants and law enforcement officials expressed differing perspectives about warrants, kit confiscation, and arrests. Facilitating communication between BCTHN program participants and other stakeholders may address some of the confusion and remove potential barriers to further improving program outcomes. Naloxone administration by law enforcement would require policies to address jurisdiction/authorization and liability issues.

Contrast blush in pediatric blunt splenic trauma does not warrant the routine use of angiography and embolization.

Science.gov (United States)

Bansal, Samiksha; Karrer, Frederick M; Hansen, Kristine; Partrick, David A

2015-08-01

Splenic artery embolization (SAE) in the presence of contrast blush (CB) has been recommended to reduce the failure rate of nonoperative management. We hypothesized that the presence of CB on computed tomography has minimal impact on patient outcomes. A retrospective review was conducted of all children (splenic trauma over a 10-year period at a level 1 pediatric trauma center. Data are presented as mean ± standard error of mean. Seven hundred forty children sustained blunt abdominal trauma, of which 549 had an identified solid organ injury. Blunt splenic injury was diagnosed in 270 of the 740 patients. All patients were managed nonoperatively without SAE. CB was seen on computed tomography in 47 patients (17.4%). There were no significant differences in the need for blood transfusion (12.5% vs 11.1%) or length of stay (3.1 vs 3.3 days) or need for splenectomy when compared in children with or without CB. Pediatric trauma patients with blunt splenic injuries can be safely managed without SAE and physiologic response and hemodynamic stability should be the primary determinants of appropriate management. Copyright © 2015 Elsevier Inc. All rights reserved.

Chronic rectal bleeding after high dose conformal treatment of prostate cancer warrants modification of existing morbidity scales

International Nuclear Information System (INIS)

Hanlon, A.L.; Schulthiess, T.E.; Hunt, M.A.; Movsas, B.; Peter, R.; Hanks, G.E.

1996-01-01

Purpose: Serious late morbidity (Grade (3(4))) from the conformal treatment of prostate cancer has been reported in <1% to 6% of patients. This study demonstrates that the reported frequency of Grade (3(4)) complications varies by the morbidity scale selected and that no existing morbidity scale adequately represents chronic rectal bleeding, which is our most frequent persisting late sequela of high dose conformal treatment. Materials and Methods: Between (5(89)) and (12(93)), 352 patients with T1-3 NXM0 prostate cancers were treated with our 4-field conformal technique without special rectal blocking. This technique includes a 1 cm margin from the CTV to the PTV in all directions. The median follow-up for these patients was 38 mos (4 to 78), and the median ICRU reporting point dose was 74 Gy (63 to 81). Patients are followed at six month intervals, and no patient is lost to follow-up. Three morbidity scales are assessed, the RTOG, the late effects group (LENT), and our modification of the LENT (FC-LENT). This modification registers chronic rectal bleeding requiring more than two coagulations as a grade 3 event. Estimates for Grade (3(4)) late GI complication rates were determined using Kaplan-Meier methodology. Differences in morbidity rates were evaluated using the log-rank test and differences in time to latency of complications were evaluated using the nonparametric Wilcoxon test. The duration of severe symptoms with chronic rectal bleeding is measured from the first to the last transrectal coagulation. Results: Sixteen patients developed Grade (3(4)) complications by one of the three morbidity scales. Two patients required surgery (colostomy, sigmoid resection), 5 required a transfusion, and 9 required more than two coagulations. The median latency to the third coagulation (plus or minus transfusions) was 24 mos (17 to 40). The median duration of bleeding between the first and last coagulation was 6 mos (3 to 25), illustrating the chronicity of this problem. The median latency for the other Grade (3(4)) complications (surgery or transfusion alone) was 10 mos (9 to 32). This latency is significantly shorter than for three or more coagulations (p=.01). The five year actuarial rate of Grade (3(4)) complications by each scale are: RTOG .7%, LENT 2%, FC-LENT 6% (p=.002). The rate of chronic rectal bleeding increases with increasing dose and is low in patients treated with conventional technique due to lower doses. Conclusions: (1) Chronic rectal bleeding is our most frequent complication of conformal treatment of prostate cancer requiring multiple coagulations or transfusions. This complication appears later in follow-up (24 mos versus 10 mos) and is present for a long duration (6 mos). We believe this justifies the inclusion of chronic rectal bleeding requiring multiple procedures as a Grade 3 event. Special rectal blocking that reduces the rectal margin around the prostate for some or all of the treatment reduces the frequency of chronic rectal bleeding, although one must be very cautious to not shield cancers occupying the posterior lobe; of the prostate. (2) Our data illustrates that published morbidity rates are highly dependent on the morbidity scale selected, as our data show .7% RTOG, 2% LENT and 6% with the FC-LENT. Obviously, a uniform scale is required that includes the serious late effects associated with the conformal treatment of prostate cancer

Chronic rectal bleeding after high-dose conformal treatment of prostate cancer warrants modification of existing morbidity scales

International Nuclear Information System (INIS)

Hanlon, Alexandra L.; Schultheiss, Timothy E.; Hunt, Margie A.; Movsas, Benjamin; Peter, Ruth S.; Hanks, Gerald E.

1997-01-01

Purpose: Serious late morbidity (Grade (3(4))) from the conformal treatment of prostate cancer has been reported in <1% to 6% of patients based on existing late gastrointestinal (GI) morbidity scales. None of the existing morbidity scales include our most frequently observed late GI complication, which is chronic rectal bleeding requiring multiple fulgerations. This communication documents the frequency of rectal bleeding requiring multiple fulgerations and illustrates the variation in reported late serious GI complication rates by the selection of morbidity scale. Methods and Materials: Between May 1989 and December 1993, 352 patients with T1-T3 nonmetastatic prostate cancers were treated with our four-field conformal technique without special rectal blocking. This technique includes a 1-cm margin from the clinical target volume (CTV) to the planning target volume (PTV) in all directions. The median follow-up for these patients was 36 months (range 2-76), and the median center of prostate dose was 74 Gy (range 63-81). Three morbidity scales are assessed: the Radiation Therapy Oncology Group (RTOG), the Late Effects Normal Tissue Task Force (LENT), and our modification of the LENT (FC-LENT). This modification registers chronic rectal bleeding requiring at least one blood transfusion and/or more than two coagulations as a Grade 3 event. Estimates for Grade (3(4)) late GI complication rates were determined using Kaplan-Meier methodology. The duration of severe symptoms with chronic rectal bleeding is measured from the first to the last transrectal coagulation. Latency is measured from the end of radiotherapy to surgery, first blood transfusion, or third coagulation procedure. Results: Sixteen patients developed Grade (3(4)) complications by one of the three morbidity scales. Two patients required surgery (colostomy or sigmoid resection), three required multiple blood transfusions, two required one or two blood transfusions, and nine required at least three coagulations. The median duration of bleeding for those patients requiring multiple procedures was 7 months (range 3-33) and the median latency was 22 months (range 9-40). The 5-year actuarial rate of Grade (3(4)) complications by each scale are: RTOG 0.7%, LENT 2%, and FC-LENT 6%. The rate of chronic rectal bleeding increases with increasing dose and is low in patients treated with conventional techniques owing to lower doses. Conclusion: Chronic rectal bleeding requiring any blood transfusion(s) or multiple coagulation procedures is our most frequently observed complication. This complication appears late in follow-up and is present for a long duration. We believe this justifies the inclusion of chronic rectal bleeding requiring multiple coagulation procedures as a Grade 3 event in future morbidity scales. Our data illustrate that published Grade (3(4)) morbidity rates are highly dependent on the morbidity scale selected, as our data show 0.7% RTOG, 2% LENT, and 6% FC-LENT. Obviously, a uniform scale is required that includes the newly recognized serious late effects associated with the conformal treatment of prostate cancer

Do all patients with idiopathic pulmonary fibrosis warrant a trial of therapeutic intervention? A pro-con perspective.

Science.gov (United States)

Moodley, Yuben; Corte, Tamera; Richeldi, Luca; King, Talmadge E

2015-04-01

Idiopathic pulmonary fibrosis (IPF) is an incurable condition that is characterized by progressive pulmonary fibrosis, architectural distortion of the lung and loss of gas exchange units. Until recently, there was no effective treatment for this condition. However, there were two landmark trials published earlier this year, which have changed the management of this condition. Pirfenidone (Assessment of Pirfenidone to Confirm Efficacy and Safety in Idiopathic Pulmonary Fibrosis trial) and nintedanib (Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis-1 and -2 trials) have both demonstrated positive outcomes in patients with IPF. In this perspective, we critically discuss the role of these agents in IPF and in the broader pulmonary fibrosis population. © 2015 Asian Pacific Society of Respirology.

How much complexity is warranted in a rainfall-runoff model? Findings obtained from symbolic regression, using Eureqa

Science.gov (United States)

Abrahart, R. J.; Beriro, D. J.

2012-04-01

The information content in a rainfall-runoff record is sufficient to support models of only very limited complexity (Jakeman and Hornberger, 1993). This begs the question of what limits should observed data place on the allowable complexity of rainfall-runoff models? Eureqa1 (Schmidt and Lipson, 2009) - pronounced "eureka" - is a software tool for finding equations and detecting mathematical relationships in a dataset. The challenge, for both software and modeller, is to identify, by means of symbolic regression, the simplest mathematical formulas which describe the underlying mechanisms that produced the data. It actually delivers, however, a series of preferred modelling solutions comprising one champion for each specific level of complexity i.e. related to solution enlargement involving the progressive incorporation of additional permitted factors (internal operators/ external drivers). The potential benefit of increased complexity can as a result be assessed in a rational manner. Eureqa is free to download and use; and, in the current study, has been employed to construct a set of rainfall-runoff transfer function models for the Annapolis River at Wilmot, in north-western Nova Scotia, Canada. The climatic conditions in this catchment present an interesting set of modelling challenges; daily variations and seasonal changes in temperature, snowfall and retention result in great difficulty for runoff prediction by means of a data-driven approach. Data from 10 years of daily observations are used in the present study (01/01/2000-31/12/2009): comprising [i] discharge, [ii] total rainfall (excluding snowfall), [iii] total snowfall, [iv] thickness of snow cover, and [v] maximum and [vi] minimum temperature. Precipitation occurs throughout the whole year being slightly lower during summer. Snowfall is common from November until April and rare hurricane weather may occur in autumn. The average maximum temperature is below 0 0C in January and February, but significant variation may result, producing milder weather and snowmelt throughout the winter. The average minimum temperature is below 0 0C during half of the year, such that freezing and melting occur frequently. The principal rainfall-runoff drivers are found to be lagged discharge and lagged precipitation, as expected. The complexity-accuracy trade-off, is nevertheless found to exhibit threshold behaviour, in which snow cover is eventually included at higher levels of complexity to account for multifaceted cold season processes.

Hepatitis A vaccine. A new convenient single-dose schedule with booster when long-term immunization is warranted

DEFF Research Database (Denmark)

Victor, J; Knudsen, J D; Nielsen, L P

1994-01-01

A total of 162 anti-HAV-negative healthy adults were immunized with a single high dose (1440 ELISA units = 1 ml) of inactivated hepatitis A vaccine and a booster was given at month 6. Antibodies were measured after modification of a commercial ELISA kit, enabling quantification of titres down to 6...

When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council.

Science.gov (United States)

Simpson, Eric L; Bruin-Weller, Marjolein; Flohr, Carsten; Ardern-Jones, Michael R; Barbarot, Sebastien; Deleuran, Mette; Bieber, Thomas; Vestergaard, Christian; Brown, Sara J; Cork, Michael J; Drucker, Aaron M; Eichenfield, Lawrence F; Foelster-Holst, Regina; Guttman-Yassky, Emma; Nosbaum, Audrey; Reynolds, Nick J; Silverberg, Jonathan I; Schmitt, Jochen; Seyger, Marieke M B; Spuls, Phyllis I; Stalder, Jean-Francois; Su, John C; Takaoka, Roberto; Traidl-Hoffmann, Claudia; Thyssen, Jacob P; van der Schaft, Jorien; Wollenberg, Andreas; Irvine, Alan D; Paller, Amy S

2017-10-01

Although most patients with atopic dermatitis (AD) are effectively managed with topical medication, a significant minority require systemic therapy. Guidelines for decision making about advancement to systemic therapy are lacking. To guide those considering use of systemic therapy in AD and provide a framework for evaluation before making this therapeutic decision with the patient. A subgroup of the International Eczema Council determined aspects to consider before prescribing systemic therapy. Topics were assigned to expert reviewers who performed a topic-specific literature review, referred to guidelines when available, and provided interpretation and expert opinion. We recommend a systematic and holistic approach to assess patients with severe signs and symptoms of AD and impact on quality of life before systemic therapy. Steps taken before commencing systemic therapy include considering alternate or concomitant diagnoses, avoiding trigger factors, optimizing topical therapy, ensuring adequate patient/caregiver education, treating coexistent infection, assessing the impact on quality of life, and considering phototherapy. Our work is a consensus statement, not a systematic review. The decision to start systemic medication should include assessment of severity and quality of life while considering the individual's general health status, psychologic needs, and personal attitudes toward systemic therapies. Copyright © 2017 American Academy of Dermatology, Inc. All rights reserved.

77 FR 53893 - Privacy Act of 1974; Department of Homeland Security U.S. Immigration and Customs Enforcement-005...

Science.gov (United States)

2012-09-04

... to identify statistically anomalous transactions that may warrant investigation for money laundering... identify anomalies in patterns of trade. Such anomalies can indicate trade-based money laundering or other... transactions that may warrant investigation for money laundering or other import-export crimes. DARTTS is...

76 FR 49497 - Privacy Act of 1974; Department of Homeland Security/United States Secret Service-001 Criminal...

Science.gov (United States)

2011-08-10

...; forensic examination information; search warrants and search warrant returns; indictments; certified.... To an agency, organization, or individual for the purpose of performing audit or oversight operations as authorized by law, but only such information as is necessary and relevant to such audit or...

78 FR 44455 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-07-24

... protects human health and the environment because the groundwater contamination has been reduced below... eligible for Fund-financed remedial actions if future conditions warrant such actions. Because EPA... for future response actions, should future conditions warrant such actions. IV. Basis for Site...

Facebook as a tool for producing sociality and connectivity

NARCIS (Netherlands)

van Dijck, J.

2012-01-01

This article investigates whether social media in general—using Facebook as an example—warrant identification of a new public sphere, another private sphere, or a different corporate sphere, as some scholars have argued. It is argued that social media platforms neither warrant a recalibration of

77 FR 35310 - Revisions to the Export Administration Regulations (EAR): Control of Military Training Equipment...

Science.gov (United States)

2012-06-13

... for foreign made ``military commodities'' that incorporate more than 10% U.S.-origin ``600 series... Military Training Equipment and Related Items the President Determines No Longer Warrant Control Under the... longer warrant control under Category IX (Military Training Equipment and Training) of the United States...

75 FR 54357 - BOEMRE Information Collection Activity: 1010-0114, Subpart A-General, Revision of a Collection...

Science.gov (United States)

2010-09-07

... notifications.. 188 within 5 workdays of putting well in production status (usually oral). Follow- up with... sufficient quantity to warrant continued operation and production, BOEMRE uses the information to verify the... the term of the lease if additional wells will warrant continued operation and production. Ensure that...

“Lumps and Bumps”: A practical guide to minor surgery for the Core ...

African Journals Online (AJOL)

to ensure that procedures are performed safely. General principles of minor surgery - “What to cut, ... decide whether the procedure can be performed under local anaesthesia or warrants sub-speciality referral. ... produce good aesthetic results operating around the eyes or nose. Referral to Plastic Surgery is warranted to ...

Brief depression screening with the PHQ-2 associated with prognosis following percutaneous coronary intervention with paclitaxel-eluting stenting

DEFF Research Database (Denmark)

Pedersen, Susanne S.; Denollet, Johan; de Jonge, Peter

2009-01-01

Depression is associated with adverse prognosis in cardiac patients, warranting the availability of brief and valid instruments to identify depressed patients in clinical practice.......Depression is associated with adverse prognosis in cardiac patients, warranting the availability of brief and valid instruments to identify depressed patients in clinical practice....

The constitutional validity of search and seizure powers in South ...

African Journals Online (AJOL)

The Criminal Procedure Act1 had long provided the only legal basis for obtaining warrants to search and seize or to perform such actions without warrant in certain circumstances. The Criminal Procedure Act embodies the general provisions with regard to searching. Specific provisions are contained in many other Acts.

48 CFR 801.690-2 - General.

Science.gov (United States)

2010-10-01

... enter into sales agreements (see separate guidance under VA's Directives Management System). (b) A... current Intermediate Level warrant need not be reissued solely to change the title. (3) Level III (Senior... “Senior Limited” and any current Senior Limited Level warrant need not be reissued solely to change the...

Psychiatric comorbidity, red flag behaviors, and associated outcomes among office-based buprenorphine patients following Hurricane Sandy.

Science.gov (United States)

Williams, Arthur R; Tofighi, Babak; Rotrosen, John; Lee, Joshua D; Grossman, Ellie

2014-04-01

supply disruption, (3) a pre-storm history of red flag behaviors (in particular, repeat opioid-positive urines), and (4) new-onset post-storm psychiatric symptoms. Our findings highlight the relative resilience of buprenorphine as an office-based treatment modality for patients encountering a disaster with associated unanticipated service disruption. In responding to future disasters, triaging patient contact and priority based on a history of red-flag behaviors, rather than a history of psychiatric comorbidity, will likely optimize resource allocation, especially among recently enrolled patients. Additionally, patients endorsing new-onset psychiatric manifestations following disasters may be an especially high-risk group for poor outcomes, warranting further study.

Cancer patients treated with sunitinib or sorafenib have sufficient antibody and cellular immune responses to warrant influenza vaccination.

Science.gov (United States)

Mulder, Sasja F; Jacobs, Joannes F M; Olde Nordkamp, Michel A M; Galama, Joep M D; Desar, Ingrid M E; Torensma, Ruurd; Teerenstra, Steven; Mulders, Peter F A; Vissers, Kris C P; Punt, Cornelis J A; de Vries, I Jolanda M; van Herpen, Carla M L

2011-07-01

The tyrosine kinase inhibitors sorafenib and sunitinib have efficacy in several types of cancer. Recent studies indicate that these agents affect the immune system. The way it affects the immune response to influenza vaccination is unknown. The aim of this study was to elucidate the specific immune response to seasonal flu vaccination in cancer patients treated with sunitinib or sorafenib. Sunitinib- or sorafenib-treated cancer patients were vaccinated against seasonal influenza with an inactivated vaccine. Healthy controls and patients with metastatic renal cell cancer (mRCC) without systemic treatment (nontreated mRCC controls) were included for comparison. Antibody responses were measured at baseline, day 8, and day 22 by a standard hemagglutination inhibition assay and cellular T-cell responses at baseline and day 8 by proliferation assay and secretion of cytokines. Forty subjects were enrolled: 16 patients treated with sunitinib, 6 patients with sorafenib, 7 nontreated mRCC controls, and 11 healthy controls. All patients treated with sunitinib and sorafenib developed seroprotection rates comparable with controls. Functional T-cell reactivity was observed in all groups, except for patients treated with sorafenib who showed a decreased proliferation rate and IFN-γ/IL-2 production and increased IL-10 compared with healthy controls. We conclude that influenza vaccination should be recommended to cancer patients treated with sunitinib or sorafenib.

Cancer patients treated with sunitinib or sorafenib have sufficient antibody and cellular immune responses to warrant influenza vaccination

NARCIS (Netherlands)

Mulder, Sasja F.; Jacobs, Joannes F. M.; Olde Nordkamp, Michel A. M.; Galama, Joep M. D.; Desar, Ingrid M. E.; Torensma, Ruurd; Teerenstra, Steven; Mulders, Peter F. A.; Vissers, Kris C. P.; Punt, Cornelis J. A.; de Vries, I. Jolanda M.; van Herpen, Carla M. L.

2011-01-01

The tyrosine kinase inhibitors sorafenib and sunitinib have efficacy in several types of cancer. Recent studies indicate that these agents affect the immune system. The way it affects the immune response to influenza vaccination is unknown. The aim of this study was to elucidate the specific immune

Cancer patients treated with sunitinib or sorafenib have sufficient antibody and cellular immune responses to warrant influenza vaccination

NARCIS (Netherlands)

Mulder, S.F.; Jacobs, J.F.M.; Olde Nordkamp, M.A.M.; Galama, J.M.D.; Desar, I.M.E.; Torensma, R.; Teerenstra, S.; Mulders, P.F.; Vissers, K.C.P.; Punt, C.J.A.; Vries, I.J.M. de; Herpen, C.M.L. van

2011-01-01

PURPOSE: The tyrosine kinase inhibitors sorafenib and sunitinib have efficacy in several types of cancer. Recent studies indicate that these agents affect the immune system. The way it affects the immune response to influenza vaccination is unknown. The aim of this study was to elucidate the

Why Research on the Pharmacogenetics of Atypical Antipsychotic-Induced Weight Gain in Individuals with Intellectual Disabilities Is Warranted

Science.gov (United States)

Sleister, Heidi M.; Valdovinos, Maria Gabriela

2011-01-01

Weight gain is an often-observed side effect of atypical antipsychotics (AAPs) and is particularly significant in individuals with intellectual disabilities (ID). The majority of individuals treated with AAPs will gain at least 10% of their initial body weight over the course of therapy (Umbricht & Kane, 1996). One's genetic constitution is an…

Overlap of obstructive sleep apnea and bronchial asthma: Effect on asthma control

Directory of Open Access Journals (Sweden)

Mohamed Zidan

2015-04-01

Conclusion: A high index of suspicion is warranted for the overlap of OSA and asthma, particularly in the presence of obesity, GERD, and in patients with severe asthma. Individualized therapy addressing these moderating factors is warranted for optimal health outcomes. Recognition and treatment of OSA in asthmatics is an important element in improving asthma control.

28 CFR 571.41 - Procedures.

Science.gov (United States)

2010-07-01

... United States, the U.S. Pardon Attorney will forward the original of the signed and sealed warrant of... Director, Bureau of Prisons. The Warden shall deliver the original warrant to the affected inmate, and obtain a signed receipt for return to the U.S. Pardon Attorney. The Warden shall take such action as is...

[Software support for automatic (computerized) work stations for dentists].

Science.gov (United States)

Prokhonchukov, A A; Balashov, A N; Zhizhina, N A; Pelkovskiĭ, V Iu

1997-01-01

The authors describe the software for a basic computer unified system of working places for dentists specializing in oral, dental surgery and orthodontics with diaries and special entries for each section. The computer system head physician--registration office--primary examination room--rooms of dental treatment, physiotherapy, and x-ray examination--is intended for use as part of local computer network of dental clinics in the MS DOS and Windows systems. Application of the system improves the labor efficiency by up to 35% and the financial efficacy by almost 30%. It also warrants legal protection of both physicians and patients.

Automated detection of diabetic retinopathy lesions on ultrawidefield pseudocolour images.

Science.gov (United States)

Wang, Kang; Jayadev, Chaitra; Nittala, Muneeswar G; Velaga, Swetha B; Ramachandra, Chaithanya A; Bhaskaranand, Malavika; Bhat, Sandeep; Solanki, Kaushal; Sadda, SriniVas R

2018-03-01

We examined the sensitivity and specificity of an automated algorithm for detecting referral-warranted diabetic retinopathy (DR) on Optos ultrawidefield (UWF) pseudocolour images. Patients with diabetes were recruited for UWF imaging. A total of 383 subjects (754 eyes) were enrolled. Nonproliferative DR graded to be moderate or higher on the 5-level International Clinical Diabetic Retinopathy (ICDR) severity scale was considered as grounds for referral. The software automatically detected DR lesions using the previously trained classifiers and classified each image in the test set as referral-warranted or not warranted. Sensitivity, specificity and the area under the receiver operating curve (AUROC) of the algorithm were computed. The automated algorithm achieved a 91.7%/90.3% sensitivity (95% CI 90.1-93.9/80.4-89.4) with a 50.0%/53.6% specificity (95% CI 31.7-72.8/36.5-71.4) for detecting referral-warranted retinopathy at the patient/eye levels, respectively; the AUROC was 0.873/0.851 (95% CI 0.819-0.922/0.804-0.894). Diabetic retinopathy (DR) lesions were detected from Optos pseudocolour UWF images using an automated algorithm. Images were classified as referral-warranted DR with a high degree of sensitivity and moderate specificity. Automated analysis of UWF images could be of value in DR screening programmes and could allow for more complete and accurate disease staging. © 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

Computerized adaptive testing--ready for ambulatory monitoring?

DEFF Research Database (Denmark)

Rose, Matthias; Bjørner, Jakob; Fischer, Felix

2012-01-01

Computerized adaptive tests (CATs) have abundant theoretical advantages over established static instruments, which could improve ambulatory monitoring of patient-reported outcomes (PROs). However, an empirical demonstration of their practical benefits is warranted.......Computerized adaptive tests (CATs) have abundant theoretical advantages over established static instruments, which could improve ambulatory monitoring of patient-reported outcomes (PROs). However, an empirical demonstration of their practical benefits is warranted....

When pathological and radiological correlation is achieved, excision of fibroadenoma with lobular neoplasia on core biopsy is not warranted.

Science.gov (United States)

Fives, C; O'Neill, C J; Murphy, R; Corrigan, M A; O'Sullivan, M J; Feeley, L; Bennett, M W; O'Connell, F; Browne, T J

2016-12-01

The diagnosis and management of lobular neoplasia (LN) including lobular carcinoma in situ (LCIS) and atypical lobular hyperplasia (ALH) remains controversial. Current management options after a core needle biopsy (CNB) with lobular neoplasia (LN) incorporating both ALH and LCIS include excision biopsy or careful clinical and radiologic follow up. A retrospective analysis of the surgical database at Cork University Hospital was performed to identify all core needle biopsies from January 1st 2010 to 31st December 2013 with a diagnosis of FA who subsequently underwent surgical excision biopsy. All cases with associated LN including ALH and classical LCIS were selected. We excluded cases with coexistent ductal carcinoma in situ (DCIS), invasive carcinoma, LN associated with necrosis, pleomorphic lobular carcinoma in situ (PLCIS) or lesions which would require excision in their own right (papilloma, radial scar, atypical ductal hyperplasia (ADH) or flat epithelial atypia (FEA)). Cases in which the radiologic targeted mass was discordant with a diagnosis of FA were also excluded. 2878 consecutive CNB with a diagnosis of FA were identified. 25 cases had a diagnosis of concomitant ALH or classical LCIS. Our study cohort consisted of 21 women with a mean age 53 years (age range 41-70 years). The core biopsy diagnosis was of LCIS and FA in 16 cases and ALH and FA in 5 cases. On excision biopsy, a FA was confirmed in all 21 cases. In addition to the FA, residual LCIS was present in 14 cases with residual ALH in 2 cases. One of the twenty-one cases (4.8%) was upgraded to invasive ductal carcinoma on excision. Copyright © 2016 Elsevier Ltd. All rights reserved.

Your Photos Or Mine: An Examination of the Laws Governing Warranted Searches and Subpoenas for the Photojournalist's Work Product.

Science.gov (United States)

Sherer, Michael D.

Noting that there are no easy answers when a photojournalist is subjected to a legal request for his or her work products from governmental officials, this paper examines how state and federal laws and court decisions have both enhanced and inhibited a photojournalist's right to protect negatives, photographs, films, and videotapes from government…

What level of concern is warranted with respect to release of production waters on the Grand Banks of Newfoundland?

International Nuclear Information System (INIS)

Andrews, C.; Payne, J.; Guiney, J.; Lee, K.

2009-01-01

The Terra Nova, Hibernia, White Rose and Hebron offshore fields are situated in an important fishing area at the edge of the Grand Banks of Newfoundland. The offshore oil and gas industry must consider its potential effects on fisheries and the environment. This presentation discussed the potential scale and nature of any impacts at individual development sites. Most information from field and laboratory studies suggests that offshore impacts will likely be minimal with little potential for any impacts beyond individual rig sites. Fishery closure zones around rigs could occasionally act as nursery areas or marine protected areas. The authors noted that such general statements should be approached with caution given that some uncertainties remain about the effects of oil development, including the potential for chronic effects of produced water on fish and other biota. The presentation reviewed recent laboratory and field studies carried out under the Program of Energy Research and Development (PERD) to 2008. Industry Environmental Effects Management (EEM) programs in the Grand Banks are presently geared towards providing early warning of any impacts on fish health, fish quality, sediment toxicity, and primary productivity. EEM programs also help reveal new insights which are not possible through laboratory studies.

Mental health system funding of cognitive enhancement interventions for schizophrenia: summary and update of the New York Office of Mental Health expert panel and stakeholder meeting.

Science.gov (United States)

McGurk, Susan R; Mueser, Kim T; Covell, Nancy H; Cicerone, Keith D; Drake, Robert E; Silverstein, Steven M; Medialia, Alice; Myers, Robert; Bellack, Alan S; Bell, Morris D; Essock, Susan M

2013-09-01

A growing research literature indicates that cognitive enhancement (CE) interventions for people with schizophrenia can improve cognitive functioning and may benefit psychosocial functioning (e.g., competitive employment, quality of social relationships). Debate continues regarding the strength of evidence for CE and related policy implications, such as the appropriateness of funding CE services. This paper summarizes and updates a meeting of experts and stakeholders convened in 2008 by the New York Office of Mental Health to review evidence on the impact of CE for people with schizophrenia and other serious mental illnesses, and addresses whether the evidence base for CE interventions is sufficient to warrant funding. Specific recommendations based on the extant literature are provided regarding the structure and components of CE programs that should be present in order to improve cognitive and psychosocial outcomes and therefore merit consideration of funding. These recommendations may serve as a starting point in developing standards for CE programs. Establishing evidence-based practice standards for implementing CE interventions for people with serious mental illnesses may facilitate dissemination of programs that have the greatest potential for improving individuals' functional outcomes while minimizing incremental costs associated with providing CE services. Important open questions include how the performance of CE programs should be monitored and which individuals might be expected to benefit from CE as evidenced by improved functioning in their everyday lives. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

Treatment of clinical mastitis.

Science.gov (United States)

Roberson, Jerry R

2012-07-01

In summary, culture-based therapy and severity levels are key to management of clinical mastitis. Antibiotic therapy should be strongly considered for gram-positive clinical mastitis. Antibiotic therapy is not necessary for mild-to-moderate gram-negative clinical mastitis. Antibiotic therapy is warranted for practically all severe clinical mastitis as well as fluids and anti-inflammatory drugs. Clinical mastitis cases due to yeast and fungal pathogens or no growth isolates do not warrant antibiotic therapy.

Pregnancy-related venous thromboembolism and risk of occult cancer

DEFF Research Database (Denmark)

Tarp Hansen, Anette; Veres, Katalin; Horváth-Puhó, Erzsébet

2017-01-01

The cancer risk during the first year after a pregnancy-related venous thromboembolism episode is higher than expected.An aggressive search for cancer in women with pregnancy-related venous thromboembolism is probably not warranted, due to low absolute risk.......The cancer risk during the first year after a pregnancy-related venous thromboembolism episode is higher than expected.An aggressive search for cancer in women with pregnancy-related venous thromboembolism is probably not warranted, due to low absolute risk....

Pregnancy-related venous thromboembolism and risk of occult cancer

DEFF Research Database (Denmark)

Hansen, Anette Tarp; Veres, Katalin; Horváth-Puhó, Erzsébet

2017-01-01

The cancer risk during the first year after a pregnancy-related venous thromboembolism episode is higher than expected. An aggressive search for cancer in women with pregnancy-related venous thromboembolism is probably not warranted, due to low absolute risk.......The cancer risk during the first year after a pregnancy-related venous thromboembolism episode is higher than expected. An aggressive search for cancer in women with pregnancy-related venous thromboembolism is probably not warranted, due to low absolute risk....

Army Communicator. Volume 36, Number 1, Spring 2011

Science.gov (United States)

2011-01-01

as protocol , etiquette , housing, and evaluation reporting, etc. The Problem at Hand Since its formal inception on July 9th, 1918 the Army warrant...PAM 600-60 (A Guide to Protocol and Etiquette for Official Entertainment) where warrant of- ficers are placed lower in order of precedence than GS...O3s and GS-10s, for example. One final example is relevant. DA PAM 600-60 (A Guide to Protocol and Etiquette for Official Enter- tainment) contains a

TU-AB-303-05: Clinical Guidelines for Determining When An Adaptive Replan May Be Warranted for Head and Neck Patients

International Nuclear Information System (INIS)

Brock, K; Lee, C; Samuels, S; Robbe, M; Lockhart, C; Schipper, M; Matuszak, M; Eisbruch, A

2015-01-01

Purpose: Tools are now available to perform daily dose assessment in radiotherapy, however, guidance is lacking as to when to replan to limit increase in normal tissue dose. This work performs statistical analysis to provide guidance for when adaptive replanning may be necessary for head/neck (HN) patients. Methods: Planning CT and daily kVCBCT images for 50 HN patients treated with VMAT were retrospectively evaluated. Twelve of 50 patients were replanned due to anatomical changes noted over their RT course. Daily dose assessment was performed to calculate the variation between the planned and delivered dose for the 38 patients not replanned and the patients replanned using their delivered plan. In addition, for the replanned patients, the dose that would have been delivered if the plan was not modified was also quantified. Deviations in dose were analyzed before and after replanning, the daily variations in patients who were not replanned assessed, and the predictive power of the deviation after 1, 5, and 15 fractions determined. Results: Dose deviations were significantly reduced following replanning, compared to if the original plan would have been delivered for the entire course. Early deviations were significantly correlated with total deviations (p<0.01). Using the criteria that a 10% increase in the final delivered dose indicates a replan may be needed earlier in the treatment course, the following guidelines can be made with a 90% specificity after the first 5 fractions: deviations of 7% in the mean dose to the inferior constrictors and 5% in the mean dose to the parotid glands and submandibular glands. No significant dose deviations were observed in any patients for the CTV -70Gy (max deviation 4%). Conclusions: A 5–7% increase in mean dose to normal tissues within the first 5 fractions strongly correlate to an overall deviatios in the delivered dose for HN patients. This work is funded in part by NIH 2P01CA059827-16

Does the evidence about health risks associated with nitrate ingestion warrant an increase of the nitrate standard for drinking water?

Science.gov (United States)

van Grinsven, Hans JM; Ward, Mary H; Benjamin, Nigel; de Kok, Theo M

2006-01-01

Several authors have suggested that it is safe to raise the health standard for nitrate in drinking water, and save money on measures associated with nitrate pollution of drinking water resources. The major argument has been that the epidemiologic evidence for acute and chronic health effects related to drinking water nitrate at concentrations near the health standard is inconclusive. With respect to the chronic effects, the argument was motivated by the absence of evidence for adverse health effects related to ingestion of nitrate from dietary sources. An interdisciplinary discussion of these arguments led to three important observations. First, there have been only a few well-designed epidemiologic studies that evaluated ingestion of nitrate in drinking water and risk of specific cancers or adverse reproductive outcomes among potentially susceptible subgroups likely to have elevated endogenous nitrosation. Positive associations have been observed for some but not all health outcomes evaluated. Second, the epidemiologic studies of cancer do not support an association between ingestion of dietary nitrate (vegetables) and an increased risk of cancer, because intake of dietary nitrate is associated with intake of antioxidants and other beneficial phytochemicals. Third, 2–3 % of the population in Western Europe and the US could be exposed to nitrate levels in drinking water exceeding the WHO standard of 50 mg/l nitrate, particularly those living in rural areas. The health losses due to this exposure cannot be estimated. Therefore, we conclude that it is not possible to weigh the costs and benefits from changing the nitrate standard for drinking water and groundwater resources by considering the potential consequences for human health and by considering the potential savings due to reduced costs for nitrate removal and prevention of nitrate pollution. PMID:16989661

Does the evidence about health risks associated with nitrate ingestion warrant an increase of the nitrate standard for drinking water?

Science.gov (United States)

van Grinsven, Hans J M; Ward, Mary H; Benjamin, Nigel; de Kok, Theo M

2006-09-21

Several authors have suggested that it is safe to raise the health standard for nitrate in drinking water, and save money on measures associated with nitrate pollution of drinking water resources. The major argument has been that the epidemiologic evidence for acute and chronic health effects related to drinking water nitrate at concentrations near the health standard is inconclusive. With respect to the chronic effects, the argument was motivated by the absence of evidence for adverse health effects related to ingestion of nitrate from dietary sources. An interdisciplinary discussion of these arguments led to three important observations. First, there have been only a few well-designed epidemiologic studies that evaluated ingestion of nitrate in drinking water and risk of specific cancers or adverse reproductive outcomes among potentially susceptible subgroups likely to have elevated endogenous nitrosation. Positive associations have been observed for some but not all health outcomes evaluated. Second, the epidemiologic studies of cancer do not support an association between ingestion of dietary nitrate (vegetables) and an increased risk of cancer, because intake of dietary nitrate is associated with intake of antioxidants and other beneficial phytochemicals. Third, 2-3 % of the population in Western Europe and the US could be exposed to nitrate levels in drinking water exceeding the WHO standard of 50 mg/l nitrate, particularly those living in rural areas. The health losses due to this exposure cannot be estimated. Therefore, we conclude that it is not possible to weigh the costs and benefits from changing the nitrate standard for drinking water and groundwater resources by considering the potential consequences for human health and by considering the potential savings due to reduced costs for nitrate removal and prevention of nitrate pollution.

Does the evidence about health risks associated with nitrate ingestion warrant an increase of the nitrate standard for drinking water?

Directory of Open Access Journals (Sweden)

Benjamin Nigel

2006-09-01

Full Text Available Abstract Several authors have suggested that it is safe to raise the health standard for nitrate in drinking water, and save money on measures associated with nitrate pollution of drinking water resources. The major argument has been that the epidemiologic evidence for acute and chronic health effects related to drinking water nitrate at concentrations near the health standard is inconclusive. With respect to the chronic effects, the argument was motivated by the absence of evidence for adverse health effects related to ingestion of nitrate from dietary sources. An interdisciplinary discussion of these arguments led to three important observations. First, there have been only a few well-designed epidemiologic studies that evaluated ingestion of nitrate in drinking water and risk of specific cancers or adverse reproductive outcomes among potentially susceptible subgroups likely to have elevated endogenous nitrosation. Positive associations have been observed for some but not all health outcomes evaluated. Second, the epidemiologic studies of cancer do not support an association between ingestion of dietary nitrate (vegetables and an increased risk of cancer, because intake of dietary nitrate is associated with intake of antioxidants and other beneficial phytochemicals. Third, 2–3 % of the population in Western Europe and the US could be exposed to nitrate levels in drinking water exceeding the WHO standard of 50 mg/l nitrate, particularly those living in rural areas. The health losses due to this exposure cannot be estimated. Therefore, we conclude that it is not possible to weigh the costs and benefits from changing the nitrate standard for drinking water and groundwater resources by considering the potential consequences for human health and by considering the potential savings due to reduced costs for nitrate removal and prevention of nitrate pollution.

Rocketdyne Propulsion & Power DOE Operations Annual Site Environmental Report 1996

Energy Technology Data Exchange (ETDEWEB)

Tuttle, R. J. [The Boeing Company, Canoga Park, CA (United States)

1997-11-10

This annual report discusses environmental monitoring at two manufacturing and test operations sites operated in the Los Angeles area by Rocketdyne Propulsion & Power of Boeing North American. Inc. (formerly Rockwell International Corporation). These are identified as the Santa Susana Field Laboratory (SSFL and the De Soto site. The sites have been used for manufacturing; R&D, engineering, and testing in a broad range of technical fields, primarily rocket engine propulsion and nuclear reactor technology. The De Soto site essentially comprises office space and light industry with no remaining radiological operations, and has little potential impact on the environment. The SSFL site, because of its large size (2.668 acres), warrants comprehensive monitoring to ensure protection of the environment.

Buying and Selling Behavior of Individual Investors in Option-like Securities

OpenAIRE

Schmitz, Philipp; Weber, Martin

2007-01-01

We analyze the trading behavior of individual investors in option-like securities, namely bank-issued warrants, and thus expand the growing literature of investors behavior to a new kind of securities. A unique data set from a large German discount broker gives us the opportunity to analyze the trading behavior of 1,454 investors, making 89,958 transactions in 6,724 warrants on 397 underlyings. In different logit regression, we make use of the facts that investors can speculate on rising and ...

Potential Impact of Diet on Treatment Effect from Anti-TNF Drugs in Inflammatory Bowel Disease

DEFF Research Database (Denmark)

Andersen, Vibeke; Hansen, Axel Kornerup; Heitmann, Berit Lilienthal

2017-01-01

We wanted to investigate the current knowledge on the impact of diet on anti-TNF response in inflammatory bowel diseases (IBD), to identify dietary factors that warrant further investigations in relation to anti-TNF treatment response, and, finally, to discuss potential strategies for such invest...... inflammation and potentially impact treatment response to anti-TNF drugs. Further studies using hypothesis-driven and data-driven strategies in prospective observational, animal and interventional studies are warranted.......We wanted to investigate the current knowledge on the impact of diet on anti-TNF response in inflammatory bowel diseases (IBD), to identify dietary factors that warrant further investigations in relation to anti-TNF treatment response, and, finally, to discuss potential strategies......% CI: 1.73-4.31, p impact of diet on anti-TNF treatment response for clinical use is scarce. Here we propose a mechanism by which Western style diet high in meat and low in fibre may promote colonic...

75 FR 2549 - Office of Biotechnology Activities; Office of Science Policy; Office of the Director; Notice of a...

Science.gov (United States)

2010-01-15

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology... Coordinator, Office of Biotechnology Activities, Office of Science Policy, Office of the Director, National..., Office of Biotechnology Activities, National Institutes of Health. [FR Doc. 2010-730 Filed 1-14-10; 8:45...

Intercomparison 2003 for Radon measurement services at PSI

CERN Document Server

Butterweck, G

2003-01-01

Twelve radon measurement services participated in the 2003 Radon Intercomparison Exercise performed at the Reference Laboratory for Radon Gas Activity Concentration Measurements at Paul Scherrer Institut (PSI) during March 13th to 24th, 2003. Ten of these laboratories were approved by the Swiss Federal Office of Public Health and their participation in the intercomparison exercise was a requirement to warrant quality of measurement. Radon gas detectors (etched-track and electret ionisation chambers) and instruments (ionisation chambers and electrostatic precipitation) were exposed in the PSI Radon Chamber in a reference atmosphere with an average radon gas concentration of 1950 Bqm sup - sup 3 leading to a radon gas exposure of 517 kBqhm sup - sup 3. Additional five electret-detectors of an approved measuring service were purchased by the Swiss Federal Office of Public Health for a spot check. Two of these were exposed as described above, two had an exposure of 247 kBqhm sup - sup 3 at an average radon concen...

49 CFR 800.25 - Delegation to the Directors of Office of Aviation Safety, Office of Railroad Safety, Office of...

Science.gov (United States)

2010-10-01

... Office of Aviation Safety, Office of Railroad Safety, Office of Highway Safety, Office of Marine Safety... Offices of Aviation, Railroad, Highway, Marine, and Pipeline and Hazardous Materials Safety, the authority... 49 Transportation 7 2010-10-01 2010-10-01 false Delegation to the Directors of Office of Aviation...

76 FR 28793 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of...

Science.gov (United States)

2011-05-18

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of Meeting Pursuant to section 10(a) of... Hill, NSABB Program Assistant, NIH Office of Biotechnology Activities, 6705 Rockledge Drive, Suite 750...

76 FR 3918 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of...

Science.gov (United States)

2011-01-21

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of Meeting Pursuant to section 10(a) of... Assistant NIH Office of Biotechnology Activities, 6705 Rockledge Drive, Suite 750, Bethesda, Maryland 20892...

76 FR 77240 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of...

Science.gov (United States)

2011-12-12

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of Meeting Pursuant to section 10(d) of..., NSABB Program Assistant, NIH Office of Biotechnology Activities, 6705 Rockledge Drive, Suite 750...

77 FR 66624 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of...

Science.gov (United States)

2012-11-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of Meeting Pursuant to section 10(a) of..., Maryland 20892. Contact Person: Ronna Hill, NSABB Program Assistant, NIH Office of Biotechnology Activities...

75 FR 58410 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of...

Science.gov (United States)

2010-09-24

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of Meeting Pursuant to section 10(a) of..., NSABB Program Assistant, NIH Office of Biotechnology Activities, 6705 Rockledge Drive, Suite 750...

Office of the Chief Financial Officer Annual Report 2009

Energy Technology Data Exchange (ETDEWEB)

Fernandez, Jeffrey

2009-12-15

Presented is the 2009 Chief Financial Officer's Annual Report. The data included in this report has been compiled from the Budget Office, the Controller, Procurement and Property Management and the Sponsored Projects Office.

76 FR 5391 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director

Science.gov (United States)

2011-01-31

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology Activities, Office of Science Policy, Office of the Director Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Science Advisory Board for Biosecurity (NSABB), February...

IEEE Std 1205-1993: IEEE guide for assessing, monitoring, and mitigating aging effects on Class 1E equipment used in nuclear power generating stations

International Nuclear Information System (INIS)

Anon.

1993-01-01

The guidelines are provided for assessing, monitoring, and mitigating degradation of Class 1E equipment used in nuclear power generating stations due to aging. The methods described can be used to identify the performance capability of Class 1E equipment beyond its qualified life. A discussion of stressors and aging mechanisms is included. If aging considerations have been satisfactorily addressed through other means (e.g., equipment qualification), then use of this guide may not be warranted. For some equipment, only partial application of this guide may be warranted

Study on the Future of Mutual Recognition in Criminal Matters in the European Union

DEFF Research Database (Denmark)

Vestergaard, Jørn; Adamo, Silvia

2008-01-01

Practitioners in the criminal justice system are fairly content with the European Arrest Warrant and other schemes based on the principle of mutual recognition of judicial decisions. This is the result of a survey published by Professor of Criminal Law Jørn Vestergaard and research asststant Silvia...... Adamo from The Faculty of Law, University of Copenhagen. In recent years, the principle  of mutual recognition has become a cornerstone in police and criminal law cooperation between Member States. In particular, the European Arrest Warrant has come to play an important role. The pivotal point...

75 FR 15713 - Office of Biotechnology Activities; Office of Science Policy; Office of the Director; Notice of a...

Science.gov (United States)

2010-03-30

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology... Lewallen, Advisory Committee Coordinator, Office of Biotechnology Activities, Office of Science Policy..., Director, Office of Biotechnology Activities, National Institutes of Health. [FR Doc. 2010-6970 Filed 3-29...

A Firsthand Comparison of a System Office to a College Office

Science.gov (United States)

Hom, Willard C.

2010-01-01

System offices for community college institutional research differ in many ways from campus offices for community college institutional research. The other chapters in this volume describe salient characteristics of system IR offices, but many readers may want to see a direct comparison of system IR offices to campus IR offices in the community…

Public hearing process for nuclear power plants. Seminar report

International Nuclear Information System (INIS)

1979-02-01

On June 26 and 27, 1978, the Nuclear Regulatory Commission conducted a seminar on the public hearing process for nuclear power plants. The seminar was intended to examine current practices regarding the conduct of public hearings and how these practices related to the statutory intent, to assess whether existing procedures are being followed, and to explore whether administrative or legal changes are warranted. The seminar format allowed exchanges of views among participants in the hearing process and was attended by members of the public, the General Accounting Office, Congressional staffs, NRC, and the nuclear industry. The report contains panel reports on scheduling of public hearings, procedures for Board notification, selection and training of panel members, hearing procedures, and Board functions

Guide for environmental radiological surveillance at ERDA installations

International Nuclear Information System (INIS)

Corley, J.P.; Denham, D.H.; Michels, D.E.; Olsen, A.R.; Waite, D.A.

1977-03-01

This Guide is intended to: Provide recommended methods, procedures, and performance criteria to bring greater comparability to ERDA environmental monitoring and reporting systems; provide ERDA management, particularly the Headquarters' Division of Safety, Standards, and Compliance (SSC) and field offices, with a broad review of accepted radiological surveillance practices for use in the evaluation of environmental surveillance programs at ERDA facilities; and delineate the capabilities and limitations of the various environmental monitoring systems for radioactivity currently used at ERDA sites, including technical areas where there is either an inadequate basis for procedural selection or where further developmental work may be warranted. The discussion of equipment, measurement techniques, and quality control procedures, although believed to represent current technology, is subject to continuing change as technological improvements become available

Evaluating Health Advice in a Web 2.0 Environment: The Impact of Multiple User-Generated Factors on HIV Advice Perceptions.

Science.gov (United States)

Walther, Joseph B; Jang, Jeong-Woo; Hanna Edwards, Ashley A

2018-01-01

Unlike traditional media, social media systems often present information of different types from different kinds of contributors within a single message pane, a juxtaposition of potential influences that challenges traditional health communication processing. One type of social media system, question-and-answer advice systems, provides peers' answers to health-related questions, which yet other peers read and rate. Responses may appear good or bad, responders may claim expertise, and others' aggregated evaluations of an answer's usefulness may affect readers' judgments. An experiment explored how answer feasibility, expertise claims, and user-generated ratings affected readers' assessments of advice about anonymous HIV testing. Results extend the heuristic-systematic model of persuasion (Chaiken, 1980) and warranting theory (Walther & Parks, 2002). Information that is generally associated with both systematic and heuristic processes influenced readers' evaluations. Moreover, content-level cues affected judgments about message sources unexpectedly. When conflicting cues were present, cues with greater warranting value (consensus user-generated ratings) had greater influence on outcomes than less warranted cues (self-promoted expertise). Findings present a challenge to health professionals' concerns about the reliability of online health information systems.

37 CFR 1.414 - The United States Patent and Trademark Office as a Designated Office or Elected Office.

Science.gov (United States)

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false The United States Patent and Trademark Office as a Designated Office or Elected Office. 1.414 Section 1.414 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES International Processing...

ANALYSIS OF PUBLIC COURT-ORDERED-DEBT DISCLOSURE: INFLUENCE OF LEGISLATION AND FUNDAMENTALS OF ACCOUNTING THEORY

Directory of Open Access Journals (Sweden)

Lucas Oliveira Gomes Ferreira

2012-03-01

Full Text Available The purpose of the present study is to analyze the accounting disclosure of judicial payments warrants (precatórios, issued when governmental entities are found liable for pecuniary awards in lawsuits according to accounting theory, and to verify if the current legislation interferes in the accounting treatment of these instruments. In this sense, we performed a documental and literature review about the legal framework and accounting procedures adopted, as well gathered data from the National Treasury Secretariat Data Collection System (SISTN in the period 2004-2009 and consulted a study carried out by the Supreme Court (STF in 2004. The study’s justification is based on the perception that over than a half of judicial payment warrants are not registered in the public accounts. Consequently, whereas these warrants (i vested rights of the plaintiffs and (ii debts of the public entity, the lack of accounting disclosure jeopardizes both the beneficiary, whose right is not reflected in the public accounts, thus casting doubt on the expectation to receive payment, and government managers and society, who do not have reliable information that allows effective management. The innovation of this paper consists of discussing identification of the appropriate moment of the generating event of the underlying debts and the proposal of disclosure considering the risk classification. In conclusion, the influence of the current legislation and the failure to observe accounting fundamentals are among the likely factors that have affected the proper accounting of judicial payment warrants within the Brazilian public administration.

Solidification and vitrification life-cycle economics study

International Nuclear Information System (INIS)

Gimpel, R.F.

1992-01-01

Solidification (making concrete) and vitrification (making glass) are frequently the treatment methods recommended for treating inorganic or radioactive wastes. Ex-situ solidification and vitrification are the competing methods for treating in excess of 450 000 cm 3 of low-level radioactive and mixed wastes at the Fernald Environmental Management Project (FEMP) located near Cincinnati, Ohio. This paper summarizes a detailed study done to: (1) compare the economics of the solidification and vitrification processes, (2) determine if the stigma assigned to vitrification is warranted and, (3) determine if investing millions of dollars into vitrification development, along with solidification development, at Fernald is warranted

A pilot study to evaluate the effects of floatation spa treatment on patients with osteoarthritis.

Science.gov (United States)

Hill, S; Eckett, M J; Paterson, C; Harkness, E F

1999-12-01

To conduct a preliminary investigation of the effects on floatation spa therapy on quality of life in patients with osteoarthritis to see if controlled trials are warranted. Uncontrolled clinical trial. Private floatation spa therapy centre. Fourteen patients with chronic osteoarthritis of the weight-bearing joints, of whom four dropped out. Six weekly sessions of floatation spa therapy. SF36, AIMS2 and MYMOP quality-of-life questionnaires. All patients improved. Differences between baseline and discharge scores showed statistically significant improvement for MYMOP, but not AIMS2 or SF-36. Controlled trials of floatation spa therapy for patients with osteoarthritis are warranted.

Effects of office innovation on office workers' health and performance

NARCIS (Netherlands)

Meijer, Eline M.; Frings-Dresen, Monique H. W.; Sluiter, Judith K.

2009-01-01

The implementation of an innovative office concept (e.g. open-plan, flexible workplaces and a paperless office concept) on health and productivity among office workers was evaluated with questionnaires of 138 workers at baseline and 6 and 15 months afterwards. Work-related fatigue, general health,

Office Hysteroscopy

OpenAIRE

Hikmet Hassa; Basar Tekin; H. Mete Tanir; Bulent Cakmak

2007-01-01

Although hysteroscopy has evolved in recent years, its use in the office setting was not made practical until early 1980s with the introduction of small caliber hysteroscopes of less than 5- mm outer diameter.This innovation simplifies ambulatory uterine exploration and the office evaluation of patients with abnormal uterine bleeding. This article reviews current trends in office hysteroscopy and its areas of application in different forms of gynecological problems.

75 FR 10293 - Office of Biotechnology Activities; Office of Science Policy; Office of the Director; Notice of a...

Science.gov (United States)

2010-03-05

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology... meeting, please contact Ms. Laurie Lewallen, Advisory Committee Coordinator, Office of Biotechnology...: March 1, 2010. Amy P. Patterson, Director, Office of Biotechnology Activities, National Institutes of...

Office 2013 simplified

CERN Document Server

Marmel, Elaine

2013-01-01

A basic introduction to learn Office 2013 quickly, easily, and in full color Office 2013 has new features and tools to master, and whether you're upgrading from an earlier version or using the Office applications for the first time, you'll appreciate this simplified approach. Offering a clear, visual style of learning, this book provides you with concise, step-by-step instructions and full-color screen shots that walk you through the applications in the Microsoft Office 2013 suite: Word, Excel, PowerPoint, Outlook, and Publisher.Shows you how to tackle dozens of Office 2013

Office Hysteroscopy

Directory of Open Access Journals (Sweden)

Hikmet Hassa

2007-06-01

Full Text Available Although hysteroscopy has evolved in recent years, its use in the office setting was not made practical until early 1980s with the introduction of small caliber hysteroscopes of less than 5- mm outer diameter.This innovation simplifies ambulatory uterine exploration and the office evaluation of patients with abnormal uterine bleeding. This article reviews current trends in office hysteroscopy and its areas of application in different forms of gynecological problems.

28 CFR 0.118 - Office of Chief Administrative Hearing Officer.

Science.gov (United States)

2010-07-01

... Officer. 0.118 Section 0.118 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Executive Office for Immigration Review § 0.118 Office of Chief Administrative Hearing... Law Judges in performance of their duties in accordance with 8 U.S.C. 1324 A and B. ...

Office 365 For Dummies

CERN Document Server

Withee, Ken

2012-01-01

The information you need to create a virtual office that can be accessed anywhere Microsoft Office 365 is a revolutionary technology that allows individuals and companies of all sizes to create and maintain a virtual office in the cloud. Featuring familiar Office Professional applications, web apps, Exchange Online, and Lync Online, Office 365 offers business professionals added flexibility and an easy way to work on the go. This friendly guide explains the cloud, how Office 365 takes advantage of it, how to use the various components, and the many possibilities offered by Office 365. It provi

76 FR 53935 - Delegation Authority for the Office of the Chief Financial Officer

Science.gov (United States)

2011-08-30

... Office of the Chief Financial Officer AGENCY: Office of the Secretary, HUD. ACTION: Notice of delegation of authority. SUMMARY: In this notice, the Secretary of HUD, pursuant to the Chief Financial Officers Act of 1990 (CFO Act), which established the position of the Chief Financial Officer within HUD, is...

41 CFR 109-25.104 - Acquisition of office furniture and office machines.

Science.gov (United States)

2010-07-01

... furniture and office machines. 109-25.104 Section 109-25.104 Public Contracts and Property Management... furniture and office machines. DOE offices and designated contractors shall make the determination as to whether requirements can be met through the utilization of DOE owned furniture and office machines. ...

76 FR 53939 - Order of Succession for the Office of the Chief Financial Officer

Science.gov (United States)

2011-08-30

... Office of the Chief Financial Officer AGENCY: Office of the Secretary, HUD. ACTION: Notice of Order of... Chief Financial Officer. This Order of Succession supersedes all prior Orders of Succession for the Office of the Chief Financial Officer. DATES: Effective Date: August 19, 2011. FOR FURTHER INFORMATION...

Office of Child Care

Science.gov (United States)

... for Children & Families Office of Child Care By Office Administration for Native Americans (ANA) Administration on Children, ... about the Child Care Rule > What is the Office of Child Care (OCC)? The Office of Child ...

Multi-office engineering

International Nuclear Information System (INIS)

Cowle, E.S.; Hall, L.D.; Koss, P.; Saheb, E.; Setrakian, V.

1995-01-01

This paper addresses the viability of multi-office project engineering as has been made possible in a large part by the computer age. Brief discussions are provided on two past projects describing the authors' initial efforts at multi-office engineering, and an in-depth discussion is provided on a current Bechtel project that demonstrates their multi-office engineering capabilities. Efficiencies and cost savings associated with executing an engineering project from multiple office locations was identified as a viable and cost-effective execution approach. The paper also discusses how the need for multi-office engineering came about, what is required to succeed, and where they are going from here. Furthermore, it summarizes the benefits to their clients and to Bechtel

Hanford stakeholder participation in evaluating innovative technologies: VOC product line, Passive soil vapor extraction using borehole flux tunable hybrid plasma

International Nuclear Information System (INIS)

Peterson, T.; McCabe, G.; Niesen, K.; Serie, P.

1995-05-01

A three-phased stakeholder participation program was conducted to support the Volatile Organic Compounds Arid Site Integrated Demonstration (VOC-Arid ID). The US DOE's Office of Technology Development (OTD) sponsored and directed the VOC-Arid ID. Its purpose was to develop and demonstrate new technologies for remediating VOC contamination in soil and ground water. The integrated demonstration, hosted by the Hanford site in Washington State, is being transitioned into the Department of Energy's (DOE) Plume Focus Area. The Plume Focus Area has the same basic objectives as the ID, but is broader in scope and is a team effort with technology developers and technology users. The objective is to demonstrate a promising technology once, and if results warrant deploy it broadly across the DOE complex and in private sector applications

COACH CV: The Seven Clinical Phenotypes of Concussion

Directory of Open Access Journals (Sweden)

Neil Craton

2017-09-01

Full Text Available Our understanding of the diverse physiological manifestations of concussion is changing rapidly. This has an influence on the clinical assessment of patients who have sustained a concussion. The 2017 Consensus Statement on Concussion in Sport states that numerous post-injury clinical findings, such as cognitive deficits, post-traumatic headaches, dizziness, difficulties with oculomotor function, and depression have all been associated with a poorer prognosis in concussed patients. This demonstrates that there are several potential clinical manifestations after head injury warranting clinical evaluation. We have developed an acronym to guide the office-based assessment of concussed patients to consider each of the potential clinical phenotypes. “COACH CV” prompts the clinician to evaluate for cognitive problems, oculomotor dysfunction, affective disturbances, cervical spine disorders, headaches, and cardiovascular and vestibular anomalies.

Annual Report 2008 -- Office of the Chief Financial Officer (OCFO)

Energy Technology Data Exchange (ETDEWEB)

Fernandez, Jeffrey

2008-12-22

It is with great pleasure that I present to you the 2008 Chief Financial Officer's Annual Report. The data included in this report has been compiled from the Budget Office, the Controller, Procurement and Property Management and the Sponsored Projects Office. Also included are some financial comparisons with other DOE Laboratories and a glossary of commonly used acronyms.

Characterization Report for the 92-Acre Area of the Area 5 Radioactive Waste Management Site, Nevada Test Site, Nevada

International Nuclear Information System (INIS)

Bechtel Nevada; U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office

2006-01-01

The U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office manages two low-level Radioactive Waste Management Sites at the Nevada Test Site. The Area 5 RWMS uses engineered shallow-land burial cells to dispose of packaged waste. This report summarizes characterization and monitoring work pertinent to the 92-Acre Area in the southeast part of the Area 5 Radioactive Waste Management Sites. The decades of characterization and assessment work at the Area 5 RWMS indicate that the access controls, waste operation practices, site design, final cover design, site setting, and arid natural environment contribute to a containment system that meets regulatory requirements and performance objectives for the short- and long-term protection of the environment and public. The available characterization and Performance Assessment information is adequate to support design of the final cover and development of closure plans. No further characterization is warranted to demonstrate regulatory compliance. U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office is proceeding with the development of closure plans for the six closure units of the 92-Acre Area

Characterization Report for the 92-Acre Area of the Area 5 Radioactive Waste Management Site, Nevada Test Site, Nevada

Energy Technology Data Exchange (ETDEWEB)

Bechtel Nevada; U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office

2006-06-01

The U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office manages two low-level Radioactive Waste Management Sites at the Nevada Test Site. The Area 5 RWMS uses engineered shallow-land burial cells to dispose of packaged waste. This report summarizes characterization and monitoring work pertinent to the 92-Acre Area in the southeast part of the Area 5 Radioactive Waste Management Sites. The decades of characterization and assessment work at the Area 5 RWMS indicate that the access controls, waste operation practices, site design, final cover design, site setting, and arid natural environment contribute to a containment system that meets regulatory requirements and performance objectives for the short- and long-term protection of the environment and public. The available characterization and Performance Assessment information is adequate to support design of the final cover and development of closure plans. No further characterization is warranted to demonstrate regulatory compliance. U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office is proceeding with the development of closure plans for the six closure units of the 92-Acre Area.

Physician offices marketing: assessing patients' views of office visits.

Science.gov (United States)

Emmett, Dennis; Chandra, Ashish

2010-01-01

Physician offices often lack the sense of incorporating appropriate strategies to make their facilities as marketer of their services. The patient experience at a physician's office not only incorporates the care they receive from the physician but also the other non-healthcare related aspects, such as the behavior of non-health professionals as well as the appearance of the facility itself. This paper is based on a primary research conducted to assess what patients assess from a physician office visit.

12 CFR 1710.17 - Certification of disclosures by chief executive officer and chief financial officer.

Science.gov (United States)

2010-01-01

... officer and chief financial officer. 1710.17 Section 1710.17 Banks and Banking OFFICE OF FEDERAL HOUSING... Corporate Practices and Procedures § 1710.17 Certification of disclosures by chief executive officer and chief financial officer. The chief executive officer and the chief financial officer of an Enterprise...

Antirelapse Efficacy of Various Primaquine Regimens for Plasmodium vivax

Directory of Open Access Journals (Sweden)

D. D. Rajgor

2014-01-01

respectively P=0.004. The relapse rate was 6.89%, 1.55%, 4%, and 3.85% as per the month of recurrence; 8.2%, 2%, 4.58%, and 3.68% P=0.007 as per PCR-RFLP; and 2.73%, 1.47%, 1.55%, and 1.53% as per PCR sequencing for groups A, B, C, and D, respectively. The concordance between methods was low, 45%. Conclusion. The higher recurrence rate in no PQ as compared to PQ groups documents PQ antirelapse activity. Regimens tested were safe. However, probable resistance to PQ warrants continuous monitoring and low concordance and limitations in the methods warrant caution in interpreting.

Planning study and economic feasibility for extended life operation of light water reactor plants

International Nuclear Information System (INIS)

Negin, C.A.; Goudarzi, L.A.; Kenworthy, L.U.; Lapides, M.E.

1980-01-01

The purpose of this planning study was to perform an assessment of the engineering and economic feasibility of extended life operation of present nuclear power plant units and to recommend future programs that may be warranted by the feasibility assessments. This effort concludes, essentially, that there is sufficient economic motivation for refurbishment to warrant more extensive examination for present plants and to identify possible design modifications that would facilitate extended service life in future plants. The costs of replacing the deterioration-prone equipment in a nuclear power plant appear to represent a small portion of the total plant costs, provided downtime is not excessive. A refurbishment and economic analysis is presented

Promoting HIV risk awareness and testing in Latinos living on the U.S.-Mexico border: the Tú No Me Conoces social marketing campaign.

Science.gov (United States)

Olshefsky, Alisa M; Zive, Michelle M; Scolari, Rosana; Zuñiga, María

2007-10-01

Increased incidence of HIV/AIDS in Latinos warrants effective social marketing messages to promote testing. The Tú No Me Conoces (You Don't Know Me) social marketing campaign promoted awareness of HIV risk and testing in Latinos living on the California-Mexico border. The 8-week campaign included Spanish-language radio, print media, a Web site, and a toll-free HIV-testing referral hotline. We documented an increase in HIV testing at partner clinics; 28% of testers who heard or saw an HIV advertisement specifically identified our campaign. Improved understanding of effective social marketing messages for HIV testing in the growing Latino border population is warranted.

76 FR 67472 - Order of Succession for the Office of the Chief Information Officer

Science.gov (United States)

2011-11-01

...: Juanita Galbreath, Deputy Chief Information Officer for Cyber Security and Privacy, Office of the Chief...) Deputy Chief Information Officer, for IT Operations; (3) Deputy Chief Information Officer, for Cyber Security and Privacy; (4) Deputy Chief Information Officer, for Business and IT Modernization. These...

Editorial: dose-dependent ZnO particle-induced acute phase response in humans warrants re-evaluation of occupational exposure limits for metal oxides

DEFF Research Database (Denmark)

Vogel, Ulla Birgitte; Cassee, Flemming R.

2018-01-01

in autonomic imbalance and particle-induced pulmonary inflammation and acute phase response.The acute phase response is the systemic response to acute and chronic inflammatory states caused by for example bacterial infection, virus infection, trauma and infarction. It is characterized by differential...... studies and SAA has been causally related to the formation of plaques in the aorta in animal studies.In a recent paper in Particle and Fibre Toxicology, Christian Monse et al. provide evidence that inhalation of ZnO nanoparticles induces dose-dependent acute phase response in humans at dose levels well...

Fermilab Education Office - FAQ

Science.gov (United States)

Search The Education Office FAQ - Frequently Asked Questions Click on the question to see the answer and the difference between the Education Office and the Lederman Science Center? The Education Office is store selling logo items and science toys. The Education Office staff works on both the 15th floor of

76 FR 69031 - Order of Succession for the Office of the Chief Human Capital Officer

Science.gov (United States)

2011-11-07

... Office of the Chief Human Capital Officer AGENCY: Office of the Chief Human Capital Officer, HUD. ACTION: Notice of order of succession. SUMMARY: In this notice, the Chief Human Capital Officer for the... Human Capital Officer. DATES: Effective Date: October 20, 2011. FOR FURTHER INFORMATION CONTACT: Lynette...

Perceived office environments and occupational physical activity in office-based workers.

Science.gov (United States)

Sawyer, A; Smith, L; Ucci, M; Jones, R; Marmot, A; Fisher, A

2017-06-01

Individuals in office-based occupations have low levels of physical activity but there is little research into the socio-ecological correlates of workplace activity. To identify factors contributing to office-based workers' perceptions of the office environment and explore cross-sectional relationships between these factors and occupational physical activity. Participants in the Active Buildings study reported perceptions of their office environment using the Movement at Work Survey. A principal component analysis (PCA) was conducted on survey items. A sub-sample wore the ActivPAL3TM accelerometer for ≥3 workdays to measure occupational step count, standing, sitting and sit-to-stand transitions. Linear regression analyses assessed relationships between environmental perceptions and activity. There were 433 participants, with accelerometer data available for 115 participants across 11 organ izations. The PCA revealed four factors: (i) perceived distance to office destinations, (ii) perceived office aesthetics and comfort, (iii) perceived office social environment and (iv) perceived management discouragement of unscheduled breaks. Younger participants perceived office destinations as being closer to their desk. Younger and female participants perceived more positive office social environments; there were no other socio-demographic differences. Within the sub-sample with accelerometer data, perceived discouragement of breaks by management was related to occupational step count/hour (B = -64.5; 95% CI -109.7 to -19.2). No other environmental perceptions were related to activity or sitting. Perceived managerial discouragement of breaks could be related to meaningful decreases in occupational step count. Future research should aim to elucidate the role of the workplace socio-cultural environment in occupational walking, with a focus on the role of management. © The Author 2017. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All

Validation of the Korean Version of the Mini-Sleep Questionnaire–Insomnia in Korean College Students

Directory of Open Access Journals (Sweden)

Hee-Ju Kim, PhD, RN, OCN

2017-03-01

Conclusion: The Mini-Sleep Questionnaire–Insomnia showed acceptable reliability and validity. Yet, the limited distribution in sleep medications warrants further evaluations in the clinical population.

Promoting gynecologic cancer awareness at a critical juncture--where women and providers meet.

Science.gov (United States)

Cooper, Crystale Purvis; Gelb, Cynthia A; Rodriguez, Juan; Hawkins, Nikki A

2014-06-01

Given the absence of effective population-based screening tests for ovarian, uterine, vaginal, and vulvar cancers, early detection can depend on women and health care providers recognizing the potential significance of symptoms. In 2008, the Centers for Disease Control and Prevention's (CDC) Inside Knowledge campaign began distributing consumer education materials promoting awareness of gynecologic cancer symptoms. We investigated providers' in-office use of CDC gynecologic cancer materials and their recognition of the symptoms highlighted in the materials. We analyzed data from a national 2012 survey of US primary care physicians, nurse practitioners, and gynecologists (N = 1,380). Less than a quarter of providers (19.4%) reported using CDC gynecologic cancer education materials in their offices. The provider characteristics associated with the use of CDC materials were not consistent across specialties. However, recognition of symptoms associated with gynecologic cancers was consistently higher among providers who reported using CDC materials. The possibility that providers were educated about gynecologic cancer symptoms through the dissemination of materials intended for their patients is intriguing and warrants further investigation. Distributing consumer education materials in health care provider offices remains a priority for the Inside Knowledge campaign, as the setting where women and health care providers interact is one of the most crucial venues to promote awareness of gynecologic cancer symptoms.

A Training Method to Improve Police Use of Force Decision Making

Directory of Open Access Journals (Sweden)

Judith P. Andersen

2016-04-01

Full Text Available Police safety and use of force decisions during critical incidents are an ongoing source of concern for both police practitioners and the public. Prior research in the area of police performance reveals that psychological and physiological stress responses during critical incidents can shape the outcome of the incident, either positively or negatively. The goal of this study was to test a training method to improve use of force decision making among police. This randomized controlled pilot study consisted of training officers to apply techniques to enhance psychological and physiological control during stressful critical incidents. Of a pool of 80 police officers, potential participants were invited based on equivalent age, years of experience, physiological characteristics (i.e., body mass index [BMI] and cardiovascular reactivity, and expertise. Results revealed that the intervention group displayed significantly better physiological control, situational awareness, and overall performance, and made a greater number of correct use of force decisions than officers in the control group (all ps < .01. The relevant improvements in use of force decision-making found in this pilot study indicate that this training method warrants further investigation. Improved use of force decision making directly translates into potential lifesaving decisions for police and the civilians they are working with.

Office 2013 for dummies

CERN Document Server

Wang, Wallace

2013-01-01

Office 2013 For Dummies is the key to your brand new Office! Packed with straightforward, friendly instruction, this update to one of the bestselling Office books of all time gets you thoroughly up to speed and helps you learn how to take full advantage of the new features in Office 2013. After coverage of the fundamentals, you'll discover how to spice up your Word documents, edit Excel spreadsheets and create formulas, add pizazz to your PowerPoint presentation, and much more.Helps you harness the power of all five Office 2013 applications: Word, Excel, PowerPoint,

29 CFR 401.18 - Office.

Science.gov (United States)

2010-07-01

... 29 Labor 2 2010-07-01 2010-07-01 false Office. 401.18 Section 401.18 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT STANDARDS MEANING OF TERMS USED IN THIS SUBCHAPTER § 401.18 Office. Office means the Office of Labor-Management Standards...

12 CFR 583.13 - Office.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Office. 583.13 Section 583.13 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY DEFINITIONS FOR REGULATIONS AFFECTING SAVINGS AND LOAN HOLDING COMPANIES § 583.13 Office. The term Office means the Office of Thrift Supervision. ...

Technology Development for the Accelerator Production of Tritium

International Nuclear Information System (INIS)

Anderson, J.L.

1999-01-01

The ED and D described in this report provide technical data on the performance of all critical components of the APT facility. Results are compared with requirements given. This data will be utilized to establish confidence in the design, in the predicted plant availability, and to reduce cost when the data warrants design simplification. Thus, if at a later date it is decided to build the APT plant, this will allow the facility to be built correctly the first time, on schedule, without recourse to costly over-design. It should also speed the commissioning process and ensure that full capacity production is attained on schedule. The planning process used to develop the elements of the CTP has been described. This program is expected to provide the needed data within the projected schedule and resources. Specific schedules for delivery of data and descriptions of the needed data are contained in the Design Data Needs. The total cost of the ED and D program is on the order of 10% of the project cost and is considered a very good investment. The CTP will be judged a success when the data produced warrants design simplifications that allow reduction of design margins and cost. Present day contingency estimates for the project greatly exceed 10% and it is expected that CTP data will warrant reduction of those contingencies by more than the cost of data production. Even results that do not simplify the design or reduce cost are considered very important and successful if they firmly establish performance, so that the design is validated and the cost certified within the existing contingencies. Nevertheless, there is technical risk in some APT components that warrant careful attention. It is to be expected that some results could be disappointing and may require design changes that increase cost moderately beyond the existing contingencies or cause moderate schedule slips

12 CFR 561.34 - Office.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Office. 561.34 Section 561.34 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY DEFINITIONS FOR REGULATIONS AFFECTING ALL SAVINGS ASSOCIATIONS § 561.34 Office. The term Office means the Office as established in section 3 of the...

41 CFR 101-25.104 - Acquisition of office furniture and office machines.

Science.gov (United States)

2010-07-01

... furniture and office machines. 101-25.104 Section 101-25.104 Public Contracts and Property Management... PROCUREMENT 25-GENERAL 25.1-General Policies § 101-25.104 Acquisition of office furniture and office machines... machines. The acquisition of new items shall be limited to those requirements which are considered...

End Group Modification

DEFF Research Database (Denmark)

Jahnsen, Rasmus O; Sandberg-Schaal, Anne; Frimodt-Møller, Niels

2015-01-01

Increased incidence of infections with multidrug-resistant bacterial strains warrants an intensive search for novel potential antimicrobial agents. Here, an antimicrobial peptide analogue with a cationic/hydrophobic alternating design displaying only moderate activity against Gram-positive pathog......Increased incidence of infections with multidrug-resistant bacterial strains warrants an intensive search for novel potential antimicrobial agents. Here, an antimicrobial peptide analogue with a cationic/hydrophobic alternating design displaying only moderate activity against Gram......, the most favorable hydrophobic activity-inducing moieties were found to be cyclohexylacetyl and pentafluorophenylacetyl groups, while the presence of a short PEG-like chain had no significant effect on activity. Introduction of cationic moieties conferred no effect or merely a moderate activity...

Regulatory challenges faced first Indonesia NPPs by independent TSOs

International Nuclear Information System (INIS)

Sri Budi Utami

2010-01-01

Technical and scientific support organizations (TSOs) dedicated to supporting national regulatory authorities. At present BAPETEN has internal TSOs. Pertaining to the regulatory control of nuclear safety, security, and safeguards for nuclear power plants (NPPs), independent TSOs providing support to the safety regulatory bodies are facing a number of technical challenges to ensuring the safety of NPPs. It is essential that BAPETEN need independent TSOs in order to warrant a sufficient level of safety, security and non proliferation in building and operating of first NPP. It is essential that BAPETEN need independent TSOs in order to warrant a sufficient level of safety, security and non proliferation in building and operating of first NPPs. (author)

CHRONIC ZINC SCREENING WATER EFFECT RATIO FOR THE H-12 OUTFALL, SAVANNAH RIVER SITE

Energy Technology Data Exchange (ETDEWEB)

Coughlin, D.; Looney, B.; Millings, M.

2009-01-13

In response to proposed Zn limits for the NPDES outfall H-12, a Zn screening Water Effects Ratio (WER) study was conducted to determine if a full site-specific WER is warranted. Using standard assumptions for relating the lab results to the stream, the screening WER data were consistent with the proposed Zn limit and suggest that a full WER would result in a similar limit. Addition of a humate amendment to the outfall water reduced Zn toxicity, but the toxicity reduction was relatively small and unlikely to impact proposed Zn limits. The screening WER data indicated that the time and expense required to perform a full WER for Zn is not warranted.

Office Computers: Ergonomic Considerations.

Science.gov (United States)

Ganus, Susannah

1984-01-01

Each new report of the office automation market indicates technology is overrunning the office. The impacts of this technology are described and some ways to manage and physically "soften" the change to a computer-based office environment are suggested. (Author/MLW)

The Users Office turns 20

CERN Multimedia

2009-01-01

20 years ago, in the summer of 1989, an office was created to assist the thousands of users who come to CERN each year, working over the broad range of projects and collaborations. Chris Onions (right), head of the Users’ Office, with Bryan Pattison (left), the Office’s founder.Before the inception of the Users Office, it was common for users to spend at least an entire day moving from office to office in search of necessary documentation and information in order to make their stay official. "Though the Office has undergone various changes throughout its lifetime, it has persisted in being a welcoming bridge to facilitate the installation of visitors coming from all over the world", says Chris Onions, head of the Users Office. This September, the Office will celebrate its 20-year anniversary with a drink offered to representatives of the User community, the CERN management and staff members from the services with whom the Office is involved. &...

Preliminary Physics Motivation and Engineering Design Assessment of the National High Power Torus

Energy Technology Data Exchange (ETDEWEB)

Robert D. Woolley

2009-06-11

In April 2006, Dr. Ray Orbach, Director of the DOE Office of Science, challenged the fusion community to "propose a new facility... which will put the U.S. at the lead in world fusion science." Analysis of the gaps between expected ITER performance and the requirements of a demonstration power plant (Demo) pointed to the critical and urgent need to develop fusion-relvant plasma-material interface (PMI) solutions consistent with sustained high plasma performance. A survey of world fusion program indicated that present and planned experimental devices do not advance the PMI issue beyond ITER, and a major dedicated experimental facility is warranted. Such a facility should provide the flexibility and access needed to solve plasma boundary challenges related to divertor heat flux and particle exhaust while also developing methods to minimize hydrogenic isotope retention and remaining compatible with high plasma performance.

Preliminary Physics Motivation and Engineering Design Assessment of the National High Power Torus

International Nuclear Information System (INIS)

Woolley, Robert D.

2009-01-01

In April 2006, Dr. Ray Orbach, Director of the DOE Office of Science, challenged the fusion community to 'propose a new facility... which will put the U.S. at the lead in world fusion science'. Analysis of the gaps between expected ITER performance and the requirements of a demonstration power plant (Demo) pointed to the critical and urgent need to develop fusion-relevant plasma-material interface (PMI) solutions consistent with sustained high plasma performance. A survey of world fusion program indicated that present and planned experimental devices do not advance the PMI issue beyond ITER, and a major dedicated experimental facility is warranted. Such a facility should provide the flexibility and access needed to solve plasma boundary challenges related to divertor heat flux and particle exhaust while also developing methods to minimize hydrogenic isotope retention and remaining compatible with high plasma performance.

Auxiliary office chair

OpenAIRE

Pascual Osés, Maite

2007-01-01

The aim of this project is to develop an auxiliary office chair, which favorably will compete with the existing chairs on the market. Evolutions of ergonomical survey in the work environment and on the configuration of offices require new products which fulfill the requirements properly. In order to achieve it a survey about office chairs has been carried out: types, characteristics, ways of usage and products on the market besides a large antropometrical study and ergonomics related to work ...

Office of the Chief Financial Officer 2012 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Williams, Kim [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2013-01-31

Fiscal Year 2012 was a year of progress and change in the Office of the Chief Financial Officer (OCFO) organization. The notable accomplishments outlined below strengthened the quality of the OCFO’s stewardship and services in support of the scientific mission of Lawrence Berkeley National Laboratory (LBNL). Three strategies were key to this progress: organizational transformation aligned with our goals; process redesign and effective use of technology to improve efficiency, and innovative solutions to meet new challenges. Over the next year we will continue to apply these strategies to further enhance our contributions to the Lab’s scientific mission. What follows is the budget, funding and costs for the office for FY 2012.

No association between temperature and deaths from cardiovascular and cerebrovascular diseases during the cold season in Astana, Kazakhstan--the second coldest capital in the world.

Science.gov (United States)

Grjibovski, Andrej M; Nurgaliyeva, Nassikhat; Kosbayeva, Aliya; Menne, Bettina

2012-01-01

Several European and North American studies have reported associations between cold temperatures and mortality from diseases of the circulatory system. However, the effects of cold vary between the settings warranting further research in other parts of the world. To study associations between temperature and mortality from selected diseases of circulatory system in Astana, Kazakhstan--the second coldest capital in the world. Daily counts of deaths from hypertensive diseases (ICD-10 codes: I10-I15), ischemic heart disease (I20-I25) and cerebrovascular diseases (I60-I69) among adults 18 years and older in Astana, Kazakhstan, during cold periods (October-March) in 2000-2001 and 2006-2010 were collected from the City Registry Office. Associations between mortality and mean apparent temperature and minimum apparent temperature (average for lags 0-15) were studied using Poisson regression controlling for barometric pressure (average for lags 0-3), wind speed and effects of month, year, weekends and holidays. Analyses were repeated using mean and minimum temperatures. Overall, there were 320, 4468 and 2364 deaths from hypertensive disorders, ischemic heart disease and cerebrovascular diseases, respectively. No significant associations between either mean, mean apparent, minimum or minimum apparent temperatures were found for any of the studied outcomes. Contrary to the European findings, we did not find inverse associations between apparent temperatures and mortality from cardiovascular or cerebrovascular causes. Factors behind the lack of association may be similar to those in urban settings in Siberia, that is, centrally heated houses and a culture of wearing large volumes of winter clothes outdoors. Further research on the sensitivity of the population in Kazakhstan to climatic factors and its adaptive capacity is warranted.

Thorough in silico and in vitro cDNA analysis of 21 putative BRCA1 and BRCA2 splice variants and a complex tandem duplication in BRCA2 allowing the identification of activated cryptic splice donor sites in BRCA2 exon 11.

Science.gov (United States)

Baert, Annelot; Machackova, Eva; Coene, Ilse; Cremin, Carol; Turner, Kristin; Portigal-Todd, Cheryl; Asrat, Marie Jill; Nuk, Jennifer; Mindlin, Allison; Young, Sean; MacMillan, Andree; Van Maerken, Tom; Trbusek, Martin; McKinnon, Wendy; Wood, Marie E; Foulkes, William D; Santamariña, Marta; de la Hoya, Miguel; Foretova, Lenka; Poppe, Bruce; Vral, Anne; Rosseel, Toon; De Leeneer, Kim; Vega, Ana; Claes, Kathleen B M

2018-04-01

For 21 putative BRCA1 and BRCA2 splice site variants, the concordance between mRNA analysis and predictions by in silico programs was evaluated. Aberrant splicing was confirmed for 12 alterations. In silico prediction tools were helpful to determine for which variants cDNA analysis is warranted, however, predictions for variants in the Cartegni consensus region but outside the canonical sites, were less reliable. Learning algorithms like Adaboost and Random Forest outperformed the classical tools. Further validations are warranted prior to implementation of these novel tools in clinical settings. Additionally, we report here for the first time activated cryptic donor sites in the large exon 11 of BRCA2 by evaluating the effect at the cDNA level of a novel tandem duplication (5' breakpoint in intron 4; 3' breakpoint in exon 11) and of a variant disrupting the splice donor site of exon 11 (c.6841+1G > C). Additional sites were predicted, but not activated. These sites warrant further research to increase our knowledge on cis and trans acting factors involved in the conservation of correct transcription of this large exon. This may contribute to adequate design of ASOs (antisense oligonucleotides), an emerging therapy to render cancer cells sensitive to PARP inhibitor and platinum therapies. © 2017 Wiley Periodicals, Inc.

Medication Therapy Management and Preconception Care: Opportunities for Pharmacist Intervention

Directory of Open Access Journals (Sweden)

Natalie A. DiPietro

2014-01-01

Full Text Available As medication therapy management (MTM continues to grow in the profession of pharmacy, careful consideration as to areas for positive patient impact is warranted. Given the current gaps in preconception care in the United States, and the accessibility and expertise of the pharmacist, MTM interventions related to preconception care may be valuable. This paper describes potential for pharmacist intervention in several different areas of preconception care. Notably, targeted medication reviews may be appropriate for interventions such as folic acid recommendations, teratogenic/category X medication management, immunizations, and disease state management. Comprehensive medication reviews may be warranted for selected disease states due to complexity of interventions, such the management of diabetes. Comprehensive medication reviews may also be warranted if several targeted interventions are necessary, or if there are a several medications or disease states requiring intervention. Pharmacists also have important roles in screening, support, and referrals needed for preconception care in the context of MTM. Patients may benefit substantially from pharmacist-directed MTM services related to preconception care. In addition, depending on clinical pharmacy service contracts and billing opportunities, pharmacists may be reimbursed for providing these services, generating sustainable revenue while fulfilling an important public health need.   Type: Idea Paper

Fermilab Education Office - Physicists

Science.gov (United States)

on Education Server, but to take full advantage of all of this site's features, you should turn Custom Search Connect with the Fermilab Education Office! Facebook Fermilab Education Office Join these groups: Science Adventures Group Teacher Resource Center Group Twitter Fermilab Education Office For more

Very early disengagement and subsequent re-engagement in primary care Office Based Opioid Treatment (OBOT) with buprenorphine.

Science.gov (United States)

Hui, David; Weinstein, Zoe M; Cheng, Debbie M; Quinn, Emily; Kim, Hyunjoong; Labelle, Colleen; Samet, Jeffrey H

2017-08-01

Patients with opioid use disorder often require multiple treatment attempts before achieving stable recovery. Rates of disengagement from buprenorphine are highest in the first month of treatment and termination of buprenorphine therapy results in return to use rates as high as 90%. To better characterize these at-risk patients, this study aims to describe: 1) the frequency and characteristics of patients with very early disengagement (≤1month) from Office Based Opioid Treatment (OBOT) with buprenorphine and 2) the frequency and characteristics of patients who re-engage in care at this same OBOT clinic within 2years, among the subset of very early disengagers. This is a retrospective cohort study of adult patients enrolled in a large urban OBOT program. Descriptive statistics were used to characterize the sample and the proportion of patients with very early (≤1month) disengagement and their re-engagement. Multivariable logistic regression models were used to identify patient characteristics associated with the outcomes of very early disengagement and re-engagement. Potential predictors included: sex, age, race/ethnicity, education, employment, opioid use history, prior substance use treatments, urine drug testing, and psychiatric diagnoses. Overall, very early disengagement was unusual, with only 8.4% (104/1234) of patients disengaging within the first month. Among the subset of very early disengagers with 2years of follow-up, the proportion who re-engaged with this OBOT program in the subsequent 2years was 11.9% (10/84). Urine drug test positive for opiates within the first month (AOR: 2.01, 95% CI: 1.02-3.93) was associated with increased odds of very early disengagement. Transferring from another buprenorphine prescriber (AOR: 0.09, 95% CI: 0.01-0.70) was associated with decreased odds of very early disengagement. No characteristics were significantly associated with re-engagement. Early disengagement is uncommon; however, continued opioid use appeared to

Fermilab Education Office - Contacts

Science.gov (United States)

Search The Office of Education and Public Outreach: Contacts All telephone numbers require area code Presentations for Presenters 840-3094 Office of Education and Public Outreach Spencer Pasero spasero@fnal.gov Education Office 840-3076 Fermilab Friends for Science Education General Questions Susan Dahl sdahl@fnal.gov

Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium

Directory of Open Access Journals (Sweden)

Ruyi Huang

2015-11-01

Interpretation: This is the largest pooling study that provides improved understanding of smoking on SCLC, and further demonstrates a causal pathway through COPD that warrants further experimental study.

Strategic Materials

National Research Council Canada - National Science Library

Buhler, Carl; Burke, Adrian; Davis, Kirk; Gerhard, Michelle; Heil, Valerie; Hulse, Richard; Kwong, Ralph; Mahoney, Michael; Moran, Scott; Peek, Michael

2006-01-01

Some materials possess greater value than others. Materials that provide essential support for the nation's economic viability or enable critical military capabilities warrant special attention in security studies...

78 FR 55254 - Information Collection Being Reviewed by the Federal Communications Commission Under Delegated...

Science.gov (United States)

2013-09-10

... unfairly disadvantage the other bidders in the market by creating an asymmetry of information. Section 1... warranted, referred to the Commission's Enforcement Bureau for possible investigation and administrative...

Prevalence and Associated Factors of Eating Disorders in Weight Management Centers in Tanta, Egypt

Directory of Open Access Journals (Sweden)

Noha Eladawi

2018-01-01

Conclusions: EDs are prevalent among individuals attending the weight management centers in a northern city in Egypt. Specific management strategies are warranted to address this commonly prevalent disease.

Differential Toxicities of Intraneurally Injected Mercuric Chloride for Sympathetic and Somatic Motor Fibers: An Ultrastructural Study

Directory of Open Access Journals (Sweden)

Shih-Jung Cheng

2011-02-01

Conclusion: This study demonstrated an undue susceptibility of sympathetic fibers to mercury intoxication. The mechanisms that underlie the selective reaction of sympathetic fibers to mercury warrant further investigation.

Fugitive Felons

Data.gov (United States)

Social Security Administration — The Fugitive Felon Reporting and Tracking System (FRATS) houses fugitive data submitted by reporters (RIDs) and warrant agencies (WAIDs). It also controls and tracks...

Nickel-silver composition shows promise as catalyst for hydrogen-oxygen fuel cells

Science.gov (United States)

Magerl, J. A.; Murray, J. N.

1970-01-01

Carburized 3-1 nickel-silver preparation exhibits considerable catalytic activity, although not as high as platinum black. Cost and availability factors warrant further evaluation of nickel-silver materials.

10 CFR 1.31 - Office of the Chief Financial Officer.

Science.gov (United States)

2010-01-01

... management policy including accounting principles and standards for the agency and provides policy guidance... accounting and financial management system, including an accounting system, and financial reporting and... 10 Energy 1 2010-01-01 2010-01-01 false Office of the Chief Financial Officer. 1.31 Section 1.31...

6 CFR 7.10 - Authority of the Chief Security Officer, Office of Security.

Science.gov (United States)

2010-01-01

...) Direct and administer DHS implementation and compliance with the National Industrial Security Program in... 6 Domestic Security 1 2010-01-01 2010-01-01 false Authority of the Chief Security Officer, Office of Security. 7.10 Section 7.10 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE...

From radial head to radiocapitellar to total elbow replacement: A case report

Directory of Open Access Journals (Sweden)

Michael Hackl

2015-01-01

Conclusions: The indication for radiocapitellar arthroplasty warrants careful consideration given the results of biomechanical analysis and the early failure due to progressive ulnohumeral erosion seen in the present case.

Custodiol versus blood cardioplegia in pediatric cardiac surgery, two-center study

Directory of Open Access Journals (Sweden)

Ebtehal A. Qulisy

2016-05-01

Conclusions: Custodial cardioplegia is associated with less optimal myocardial protection and higher adverse outcomes compared to cold blood cardioplegia in children undergoing cardiac surgery. A randomized comparison is warranted.

A dynamic case definition is warranted for adequate notification in an extended epidemic setting: the Dutch Q fever outbreak 2007-2009 as exemplar.

Science.gov (United States)

Jaramillo-Gutierrez, G; Wegdam-Blans, M C; ter Schegget, R; Korbeeck, J M; van Aken, R; Bijlmer, H A; Tjhie, J H; Koopmans, M P

2013-10-10

Q fever is a notifiable disease in the Netherlands:laboratories are obliged to notify possible cases to the Municipal Health Services. These services then try to reconfirm cases with additional clinical and epidemiological data and provide anonymised reports to the national case register of notifiable diseases. Since the start of the 2007–2009 Dutch Q fever outbreak,notification rules remained unchanged, despite new laboratory insights and altered epidemiology. In this study, we retrospectively analysed how these changes influenced the proportion of laboratory-defined acute Q fever cases (confirmed, probable and possible)that were included in the national case register, during(2009) and after the outbreak (2010 and 2011).The number of laboratory-defined cases notified to the Municipal Health Services was 377 in 2009, 96 in 2010 and 50 in 2011. Of these, 186 (49.3%) in 2009, 12(12.5%) in 2010 and 9 (18.0%) in 2011 were confirmed as acute infection by laboratory interpretation. The proportion of laboratory-defined acute Q fever cases that was reconfirmed by the Municipal Health Services and that were included in the national case register decreased from 90% in 2009, to 22% and 24% in 2010 and 2011, respectively. The decrease was observed in all categories of cases, including those considered to be confirmed by laboratory criteria. Continued use ofa pre-outbreak case definition led to over-reporting of cases to the Municipal Health Services in the post-epidemic years. Therefore we recommend dynamic laboratory notification rules, by reviewing case definitions periodically in an ongoing epidemic, as in the Dutch Q fever outbreak.

Developments in IVF warrant the adoption of new performance indicators for ART clinics, but do not justify the abandonment of patient-centred measures.

Science.gov (United States)

Wilkinson, J; Roberts, S A; Vail, A

2017-06-01

Recent advances in embryo freezing technology together with growing concerns over multiple births have shifted the paradigm of appropriate IVF. This has led to the adoption of new performance indicators for ART clinics by national reporting schemes, such as those curated by the Society for Assisted Reproductive Technology (SART) and the Human Fertilization and Embryology Authority (HFEA). Using these organizations as case studies, we review several outcome measures from a statistical perspective. We describe several denominators that are used to calculate live birth rates. These include cumulative birth rates calculated from all fresh and frozen transfer procedures arising from a particular egg collection or cycle initiation, and live birth rates calculated per embryo transferred. Using data from both schemes, we argue that all cycles should be included in the denominator, regardless of whether or not egg collection and fertilization were successful. Excluding cancelled cycles reduces the impact of confounding due to patient characteristics but also removes policy and performance differences which we argue represent relevant sources of variation. It may be misleading to present prospective patients with essentially hypothetical measures of performance predicated on parity of ovarian stimulation and transfer policies. Although live birth per embryo has the advantage of encouraging single embryo transfer, we argue that it is prone to misinterpretation. This is because the likelihood of live birth is not proportional to the number of embryos transferred. We conclude that it is not possible to present a single measure that encompasses both effectiveness and safety. Instead, we propose that a set of clear, relevant outcome indicators is necessary to enable subfertile patients to make informed choices regarding whether and where to be treated. © The Author 2017. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Ecocitizen at the office

CERN Multimedia

Staff Association

2014-01-01

At the office, I do as I would at home At the office, just as at home, we need to stay warm, have light, be equipped (with office material, furniture). We thus need energy and raw materials. This consumption is not without consequences for our environment. How to reduce our consumption? In everyday life, we already have behaviours that allow us to save energy and resources, to sort our waste. At the office it is important to act in the same way as at home, as we spend a lot of time at our workplace. How to act more responsibly at the office, to reduce the environmental impact, and how to stay motivated? Computer, printer, copy machine… or coffee machine. There are quite a few electrical appliances which are indispensable in our office. Always turned on, or almost, they are also often inactive, and it is during these phases of inactivity that two thirds of their consumption occurs. The way one uses the computer is important in order to limit its consumption. Use the sleep mode with care. A c...

Office 2010 Web Apps For Dummies

CERN Document Server

Weverka, Peter

2010-01-01

Enhance your Microsoft Office 2010 experience with Office 2010 Web Apps!. Office Web Apps complement Office, making it easy to access and edit files from anywhere. It also simplifies collaboration with those who don't have Microsoft Office on their computers. This helpful book shows you the optimum ways you can use Office Web Apps to save time and streamline your work. Veteran For Dummies author Peter Weverka begins with an introduction to Office Web Apps and then goes on to clearly explain how Office Web Apps provide you with easier, faster, more flexible ways to get things done.: Walks you t

Feasibility of 4D perfusion CT imaging for the assessment of liver treatment response following SBRT and sorafenib

Directory of Open Access Journals (Sweden)

Catherine Coolens, PhD

2016-07-01

Conclusions: The proposed methodology demonstrated feasibility of evaluating spatiotemporal changes in liver tumor perfusion and normal liver function following antiangiogenic therapy and radiation treatment warranting further evaluation of biomarker prognostication.

perceived discipline, punishment and organizational performance

African Journals Online (AJOL)

Maryjoan U. Iheanacho, Department of Business Management, University of Calabar, ... financial constraint, which can be argued, warrant ... intelligence and an understanding of the impact ... fifty were successfully retrieved accounting for.

Beaufort Sea extreme wave studies assessment

National Research Council Canada - National Science Library

Murray, M. A; Maes, Marc A; Muir, Lynette R

1986-01-01

.... A systematic assessment of their respective methodologies indicated factors which would help to undo some of the conservatism in the Seaconsult estimates and warrant a slight increase in the Hydrotechnology...

13 CFR 107.800 - Financings in the form of Equity Securities.

Science.gov (United States)

2010-01-01

... of any class in a corporation, stock options, warrants, limited partnership interests in a limited partnership, membership interests in a limited liability company, or joint venture interests. If the Financing...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Science.gov (United States)

2010-01-01

... full-time community volunteer (including criminal justice volunteer, volunteer in justice, and VET... institution of higher learning; or (3) In another activity which, in the agency's view, warrants extension. (c...

Mastering VBA for Office 2010

CERN Document Server

Mansfield, Richard

2010-01-01

A comprehensive guide to the language used to customize Microsoft Office. Visual Basic for Applications (VBA) is the language used for writing macros, automating Office applications, and creating custom applications in Word, Excel, PowerPoint, Outlook, and Access. This complete guide shows both IT professionals and novice developers how to master VBA in order to customize the entire Office suite for specific business needs.: Office 2010 is the leading productivity suite, and the VBA language enables customizations of all the Office programs; this complete guide gives both novice and experience

Office 2010 Bible

CERN Document Server

Walkenbach, John; Groh, Michael R

2010-01-01

The best of the best from the bestselling authors of Excel, Word, and PowerPoint Bibles !. Take your pick of applications from the Office 2010 suite and your choice of leading experts to show you how to use them. This Office 2010 Bible features the best-of-the-best content from the Excel 2010 Bible , by "Mr. Spreadsheet" John Walkenbach; the Word 2010 Bible by Microsoft MVP Herb Tyson; the PowerPoint 2010 Bible , by PowerPoint expert Faithe Wempen; and coverage of Access 2010 from Microsoft MVP Michael Alexander. If you want to quickly and effectively begin using Office 2010, start i

Mass and power modeling of communication satellites

Science.gov (United States)

Price, Kent M.; Pidgeon, David; Tsao, Alex

1991-01-01

Analytic estimating relationships for the mass and power requirements for major satellite subsystems are described. The model for each subsystem is keyed to the performance drivers and system requirements that influence their selection and use. Guidelines are also given for choosing among alternative technologies which accounts for other significant variables such as cost, risk, schedule, operations, heritage, and life requirements. These models are intended for application to first order systems analyses, where resources do not warrant detailed development of a communications system scenario. Given this ground rule, the models are simplified to 'smoothed' representation of reality. Therefore, the user is cautioned that cost, schedule, and risk may be significantly impacted where interpolations are sufficiently different from existing hardware as to warrant development of new devices.

Minimising medically unwarranted computed tomography scans

International Nuclear Information System (INIS)

Brenner, D.J.

2012-01-01

As computed tomography (CT) is such a superb diagnostic tool and individual CT risks are small, whenever a CT scan is clinically warranted, the CT benefit/risk balance is by far in the patient’s favour. However, if a CT scan is not clinically warranted, this balance shifts dramatically. It is likely that at least 25% of CT scans fall into this latter category, in that they could either be replaced with alternative imaging modalities or could be avoided entirely. Use of clinical decision rules for CT usage represents a powerful approach for slowing down the increase in CT usage, because they have the potential to overcome some of the major factors that result in some CT scans being undertaken when they may not be clinically helpful.

Office Space: How Will Technology Affect the Education Office Environment?

Science.gov (United States)

Day, C. William

2009-01-01

The office environment 10 years from now will be different from the one today. More office personnel will be organized around processes rather than functions. More work activities will be done by teams rather than individuals, and those teams will change over time, as will the nature of the work projects and the people who constitute the team. The…

Collaborative, cross-national studies on health and safety in seafaring for evidence-based Maritime policy and regulations.

Science.gov (United States)

Jensen, Olaf C

2009-01-01

Until recently, maritime health and safety policies and regulations were sparsely based on health and safety research, and only a small number of countries contributed to new research. To strengthen maritime health and safety research activities by presenting a study example and discussing the possibilities and needs for more national and cross-national research. In a cross-national epidemiological study example, the seafarers from eleven countries completed small, anonymous questionnaires concerning the working conditions on their latest tours at sea while waiting for their health examinations. Significant disparities were pointed out among the nationalities, e.g., the length of the tours at sea, the proportional distribution of officers and non-officers, the mean age structure, the injury incidence rates, and the differences of occupational safety standards. The analysis of all data together increased the statistical strength of the multivariate analyses and allowed for valid comparisons among the nationalities. The questionnaire data was used successfully in the collaborative study example, but other data sources and methods are useful for health and safety research in seafaring as well. More national and cross-national research on maritime health and safety is warranted.

49 CFR 1325.3 - Federal office.

Science.gov (United States)

2010-10-01

... 49 Transportation 9 2010-10-01 2010-10-01 false Federal office. 1325.3 Section 1325.3... FEDERAL OFFICE OR THEIR REPRESENTATIVES § 1325.3 Federal office. For the purposes of this section, Federal office means the office of President or Vice President of the United States; or of Senator or...

Effect of interval training programme on pulse pressure in the ...

African Journals Online (AJOL)

EB

2013-09-03

Systolic Blood Pressure ... are consistent with the pathophysiological processes ... Hospitals Management Board and the faculty of ... et al13 using an automated digital electronic BP ..... however, warrants attention in future studies.

Hyperleptinemia May Protect From Cardio-Vascular Complications: A Small Georgian Study

Directory of Open Access Journals (Sweden)

Tamar Zerekidze

2014-12-01

CONCLUSION: Leptin might act as a preventive measure for cardiovascular complications only in the presence of sufficient amount of fat mass. Further studies are warranted in order to support these results.

Demographic characteristics in patients with short-gap and long-gap ...

African Journals Online (AJOL)

Further analysis of this topic is warranted ... Keywords: demographic characteristics, long-gap esophageal atresia, short-gap ... Thus, we conducted the present study to analyze the character- ..... this issue, providing fundamental information.

16 CFR 5.67 - Sanctions.

Science.gov (United States)

2010-01-01

... Disciplinary Actions Concerning Postemployment Conflict of Interest § 5.67 Sanctions. In the case of any...), the Commission may order such disciplinary action as it deems warranted, including: (a) Reprimand; (b...

45 CFR 672.12 - Prehearing conference.

Science.gov (United States)

2010-10-01

... dispute; (3) The necessity or desirability of amendments to pleadings; (4) The exchange of exhibits... forth (i) the circumstances warranting the taking of the discovery; (ii) the nature of the information...

The spectrum of gastric cancer as seen in a large quaternary ...

African Journals Online (AJOL)

Objective. This retrospective audit of a prospectively maintained central hospital ... Both these observations may simply reflect referral patterns and warrant further investigation. ..... with GC in our environment present with advanced disease.

Isolation of Treponema DNA from Necrophagous Flies in a Natural Ecosystem

Directory of Open Access Journals (Sweden)

Sascha Knauf

2016-09-01

Interpretation: Our results raise the possibility that flies play a role in yaws transmission; further research is warranted, given how important understanding transmission is for the eradication of this disfiguring disease.

75 FR 54090 - Stainless Steel Bar From India: Final Results of Antidumping Duty Administrative Review

Science.gov (United States)

2010-09-03

... methodology to Venus was not warranted because we did not find correlation between cost and price trends. See... United States (``HTSUS''). Although the HTSUS subheadings are provided for convenience and customs...

76 FR 29640 - Special Local Regulations for Marine Events; Chester River, Chestertown, MD

Science.gov (United States)

2011-05-23

... 200 yards to an anchorage location, embarking and disembarking Tea Party actors by dinghy, and then... reference Datum NAD 1983. (b) Definitions: (1) Coast Guard Patrol Commander means a commissioned, warrant...

Population genetics of four heavily exploited shark species around the Arabian Peninsula

KAUST Repository

Spaet, Julia L.Y.; Jabado, Rima W.; Henderson, Aaron C.; Moore, Alec B. M.; Berumen, Michael L.

2015-01-01

The northwestern Indian Ocean harbors a number of larger marine vertebrate taxa that warrant the investigation of genetic population structure given remarkable spatial heterogeneity in biological characteristics such as distribution, behavior

Teach yourself visually Office 2013

CERN Document Server

Marmel, Elaine

2013-01-01

Learn the new Microsoft Office suite the easy, visual way Microsoft Office 2013 is a power-packed suite of office productivity tools including Word, Excel, PowerPoint, Outlook, Access, and Publisher. This easy-to-use visual guide covers the basics of all six programs, with step-by-step instructions and full-color screen shots showing what you should see at each step. You'll also learn about using Office Internet and graphics tools, while the additional examples and advice scattered through the book give you tips on maximizing the Office suite. If you learn best when you can see how

7 CFR 1.25 - Implementing regulations for the Office of the Secretary and the Office of Communications.

Science.gov (United States)

2010-01-01

... Communications has responsibility for maintaining the flow of information to the mass communications media... Secretary and the Office of Communications. 1.25 Section 1.25 Agriculture Office of the Secretary of... Secretary and the Office of Communications. (a) For the Office of the Secretary and for the Office of...

Smart and Sustainable Offices (SSO: Showcasing a holistic approach to realise the next generation offices

Directory of Open Access Journals (Sweden)

A. Cobaleda Cordero

2018-01-01

Full Text Available The Smart Sustainable Offices project (SSO is a product of years of research with large sets of data collected from more than 30 office buildings in Switzerland, Sweden, and Spain. Based on scientific evidence, the concept of SSO, initially conceived as a research plan to address the interdependencies between office users and their working environment in a European context, is now used as a qualitative and quantitative mixed method approach for office diagnosis and ideation. At the current stage, the SSO methodology aims to implement a new paradigm of user-oriented, lower carbon footprint and resilient office design solutions. The main strategy is articulated around the “office DNA” of every organisation, decoded as a compound of work patterns, operational and individual needs, and their potential to define design criteria. The practical application of SSO and its tentative findings exemplified through three pilot test office-demonstrators are described in this paper.

12 CFR 4.4 - Washington office.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Washington office. 4.4 Section 4.4 Banks and... EXAMINERS Organization and Functions § 4.4 Washington office. The Washington office of the OCC is the main office and headquarters of the OCC. The Washington office directs OCC policy, oversees OCC operations...

Terrorist Surveillance Act of 2006. S. 3931 and Title II of S. 3929, the Terrorist Tracking, Identification, and Prosecution Act of 2006

National Research Council Canada - National Science Library

Bazan, Elizabeth B

2006-01-01

...., to address electronic surveillance programs. In addition, the measures would amend other provisions of FISA dealing with electronic surveillance without a warrant pursuant to an Attorney General certification, applications for a Foreign...

75 FR 45650 - Notice of Intent To Prepare a Resource Management Plan for the Dominguez-Escalante National...

Science.gov (United States)

2010-08-03

... for solitude and/or primitive and unconfined recreation? Is special management still warranted for the... available at any time. While you can ask us in your comment to withhold your personal identifying...

10 CFR 820.28 - Prehearing actions.

Science.gov (United States)

2010-01-01

... dispute; (3) The necessity or desirability of amendments to pleadings; (4) The exchange of exhibits; (5... forth: (i) The circumstances warranting the taking of the discovery; (ii) The nature of the information...

78 FR 66056 - Sunkhaze Meadows National Wildlife Refuge and Carlton Pond Waterfowl Production Area, Penobscot...

Science.gov (United States)

2013-11-04

... hiking, hunting, and fishing. Background The CCP Process The National Wildlife Refuge System... activities, such as wildlife observation, photography, hiking, snowmobiling, and hunting, would continue to... management (if warranted) to [[Page 66058

24 CFR 884.109 - Rent adjustments.

Science.gov (United States)

2010-04-01

... SUPPORTIVE HOUSING FOR THE ELDERLY PROGRAM AND SECTION 811 SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES... will be determined by HUD at least annually; interim revisions may be made as market conditions warrant...

Diabetic retinopathy: A predictor of coronary artery disease

Directory of Open Access Journals (Sweden)

Fawzia El Demerdash

2012-06-01

Conclusion: Diabetic retinopathy is a good predictor of coronary artery disease that exceeds the conventional risk factors. Diabetics with retinopathy would benefit from early coronary angiography and diabetic retinocoronary clinics are warranted.

76 FR 66125 - Petition for Waiver of Compliance

Science.gov (United States)

2011-10-25

... making the test * * * .'' UP feels that by allowing an employee to use their unique employee... warrant a hearing. If any interested party desires an opportunity for oral comment, they should notify FRA...

Sociodemographic disparities in the utilization of proton therapy for prostate cancer at an urban academic center

Directory of Open Access Journals (Sweden)

Kristina D. Woodhouse, MD

2017-04-01

Conclusion: Sociodemographic disparities exist in PT use for prostate cancer at an urban academic institution. Further investigation of potential barriers to access is warranted to ensure equitable distribution across all demographic groups.

Can chlorhexidine mouthwash twice daily ameliorate cyclosporine-induced gingival overgrowth?

Directory of Open Access Journals (Sweden)

Ching-Hwa Gau

2013-03-01

Conclusion: These findings suggest that chlorhexidine mouthwash used twice daily may reduce the severity of CsA-induced gingival overgrowth. Further research is warranted to determine the optimal dose and treatment regimen.

Does It Matter Where You Work? A Comparison of How Three Work Venues (Traditional Office, Virtual Office, and Home Office) Influence Aspects of Work and Personal/Family Life.

Science.gov (United States)

Hill, E. Jeffrey; Ferris, Maria; Martinson, Vjollca

2003-01-01

A comparison was made of IBM employees in traditional offices (n=4,316), virtual offices (n=767), and home offices (n=441). Home office teleworking helped balance work and family and enhanced business performance with cost savings. Virtual office teleworking was associated with less work-family balance and less successful personal/family life.…

Fermilab Education Office: Science Adventures

Science.gov (United States)

Search The Education Office: Science Adventures Adventure Catalog Search for Adventures Calendar Class Facebook Group. Contact: Science Adventures Registrar, Education Office Fermilab, MS 777, P.O. Box 500 it again." Opportunities for Instructors The Education Office has openings for instructors who

Association between risk of birth defects occurring level and arsenic concentrations in soils of Lvliang, Shanxi province of China

International Nuclear Information System (INIS)

Wu, Jilei; Zhang, Chaosheng; Pei, Lijun; Chen, Gong; Zheng, Xiaoying

2014-01-01

The risk of birth defects is generally accredited with genetic factors, environmental causes, but the contribution of environmental factors to birth defects is still inconclusive. With the hypothesis of associations of geochemical features distribution and birth defects risk, we collected birth records and measured the chemical components in soil samples from a high prevalence area of birth defects in Shanxi province, China. The relative risk levels among villages were estimated with conditional spatial autoregressive model and the relationships between the risk levels of the villages and the 15 types of chemical elements concentration in the cropland and woodland soils were explored. The results revealed that the arsenic levels in cropland soil showed a significant association with birth defects occurring risk in this area, which is consistent with existing evidences of arsenic as a teratogen and warrants further investigation on arsenic exposure routine to birth defect occurring risk. - Highlights: • Association between soil geochemical components and birth defects risk was proposed. • The relative risk difference among villages were estimated with CAR model. • Arsenic levels in cropland showed a significant association to birth defect risk. • The finding warrants further investigation on arsenic as a teratogen. - The difference of risk levels estimate by spatial statistics to birth defect significantly associated with arsenic levels in cropland soils warrants further investigation

Challenges for Democracies in Responding to Terrorism: A View from Canada and Israel

Directory of Open Access Journals (Sweden)

Jean-Sébastien Rioux

2016-08-01

Full Text Available The November 2015 terrorist attacks at the Bataclan concert hall and sidewalk cafés in Paris, the March 2016 bombing at the Brussels airport, and the mass shooting at the Pulse nightclub in Orlando, Fla. in June 2016 are just a few examples of the horror and loss of life inflicted on innocent civilians by individuals affiliated with, or supporting the Islamic State of Iraq and al-Sham (ISIS. Canada is not immune: in October 2014 two ISIS-inspired attacks, one in Saint-Jean-sur-Richelieu, Que. and one in Ottawa, resulted in the deaths of Warrant Officer Patrice Vincent and Cpl. Nathan Cirillo. More recently, ISIS vowed to make the month of Ramadan a bloodbath in Europe and America.2 Heightened awareness, attention, and concern among western democracies surround the issue of terrorism on home soil. And there are serious challenges in addressing such threats.

Engineering evaluation/cost analysis for the 233-S Plutonium Concentration Facility

International Nuclear Information System (INIS)

Rugg, J.E.

1996-08-01

The 100, 200, 300 and 1100 Areas of the Hanford Site were placed on the U. S. Environmental Protection Agency's National Priorities List in November 1989 under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Located in the 200 Area is the deactivated 233-S Plutonium Concentration Facility (used in the REDOX process). The facility has undergone severe degradation due to exposure to extreme weather conditions. An expedited response is proposed to ensure protection of human health and the environment. The Department of Energy, Richland Operations Office (RL) in cooperation with the Washington State Department of Ecology, has prepared this Engineering Evaluation/Cost Analysis pursuant to CERCLA. Based on the evaluation, RL has determined that hazardous substances in the 233-S Facility may present a potential threat to human health or the environment, and that an expedited removal action is warranted for decommissioning of the facility

Guide for: environmental radiological surveillance at US Department of Energy installations

International Nuclear Information System (INIS)

Corley, J.P.; Denham, D.H.; Jaquish, R.E.; Michels, D.E.; Olsen, A.R.; Waite, D.A.

1981-07-01

This second edition of the Guide, originally published in 1977, is presented as an interim revision and does not contain major changes in content. The original objectives and scope of the Guide have not changed. The Guide is intended to: provide recommended methods, procedures, and performance criteria to bring greater comparability to DOE environmental monitoring and reporting systems; provide DOE management, particularly the Headquarters' Operational and Environmental Safety Division (OESD) and field offices, with a broad review of accepted radiological surveillance practices for use in the evaluation of environmental surveillance programs at DOE facilities; and delineate the capabilities and limitations of the various environmental monitoring systems for radioactivity currently used at DOE sites, including technical areas where there is either an inadequate basis for procedural selection or where further development work may be warranted. The document is intended as a guide, not a manual of detailed mandatory procedure

Cervical Spine pain as a presenting complaint in metastatic pancreatic cancer: a case report.

Science.gov (United States)

Rosenberg, Emily; Buchtel, Lindsey

2016-01-01

A 48 year-old female presented to her primary care physician with a two-month history of neck pain with negative cervical spine x-rays. During that office visit, the patient was noted to be tachycardic with EKG revealing ST depressions, which led to hospital admission. Acute coronary syndrome was ruled out, however, persistent neck pain warranted inpatient MRI of the cervical spine, which revealed a cervical spine lesion. Extensive investigation and biopsy ultimately confirmed stage IV pancreatic adenocarcinoma with metastases to the bone, liver, and likely lung. In the literature, the findings of a primary metastatic site being bone is rare with only a few case reports showing vertebral or sternal metastasis as the first clinical manifestation of pancreatic cancer. The uniqueness of this case lies in the only presenting complaint being cervical spine pain in the setting of extensive metastases to the liver, bone, and likely lung.

Spatial database for intersections.

Science.gov (United States)

2015-08-01

Deciding which intersections in the state of Kentucky warrant safety improvements requires a comprehensive inventory : with information on every intersection in the public roadway network. The Kentucky Transportation Cabinet (KYTC) : had previously c...

Theft of Debris from the Space Shuttle Columbia: Criminal Penalties

National Research Council Canada - National Science Library

Murnane, Andrew W; Eig, Larry

2003-01-01

.... This report briefly describes possible criminal penalties for conversion of government property, and does not address issues related to the personal property of the Columbia's crew. This report will be updated as warranted.

Amino-terminal pro-brain natriuretic peptide in children with latent rheumatic heart disease

Directory of Open Access Journals (Sweden)

Justin P Zachariah

2016-01-01

Conclusion: Serum NT-proBNP did not distinguish between latent RHD cases and the controls. Sex and within-family exposures may confound this result. More investigation into biomarker-based RHD detection is warranted.

Untitled

African Journals Online (AJOL)

on human development are sufficiently important to warrant an integration of. HIV and .... interactions which may be disadvantageous or indeed advantageous to .... HIV -MTCT and the paediatric management of children born of seroposi-.

Office 2010 all-in-one for dummies

CERN Document Server

Weverka, Peter

2010-01-01

The leading book on Microsoft Office, now fully updated for Office 2010 Microsoft Office, the world's leading productivity suite, has been updated with new tools. Veteran Office users as well as newcomers will need the comprehensive information in this bestselling All-in-One guide. With a self-contained minibook devoted to each Office application plus minibooks on how Office works together and how you can expand its usefulness, Office 2010 All-in-One For Dummies gets you up to speed and answers the questions you'll have down the road.Microsoft Office is the office pro

Promoting Gynecologic Cancer Awareness at a Critical Juncture—Where Women and Providers Meet

Science.gov (United States)

Cooper, Crystale Purvis; Rodriguez, Juan; Hawkins, Nikki A

2015-01-01

Given the absence of effective population-based screening tests for ovarian, uterine, vaginal, and vulvar cancers, early detection can depend on women and health care providers recognizing the potential significance of symptoms. In 2008, the Centers for Disease Control and Prevention’s (CDC) Inside Knowledge campaign began distributing consumer education materials promoting awareness of gynecologic cancer symptoms. We investigated providers’ in-office use of CDC gynecologic cancer materials and their recognition of the symptoms highlighted in the materials. We analyzed data from a national 2012 survey of US primary care physicians, nurse practitioners, and gynecologists (N = 1,380). Less than a quarter of providers (19.4 %) reported using CDC gynecologic cancer education materials in their offices. The provider characteristics associated with the use of CDC materials were not consistent across specialties. However, recognition of symptoms associated with gynecologic cancers was consistently higher among providers who reported using CDC materials. The possibility that providers were educated about gynecologic cancer symptoms through the dissemination of materials intended for their patients is intriguing and warrants further investigation. Distributing consumer education materials in health care provider offices remains a priority for the Inside Knowledge campaign, as the setting where women and health care providers interact is one of the most crucial venues to promote awareness of gynecologic cancer symptoms. PMID:24214840

Instructed officers Radiation Protection

International Nuclear Information System (INIS)

2007-01-01

This law contains instructions on the prevention of radiological and contains 4 articles Article I: describe the responsibilities of the institutions that operate within the scope of radiological protection in terms of the number of radiation protection officers and personal Supervisors who available in the practices radiation field. Article II: talking about the conditions of radiation protection officers that must be available in the main officers and working field in larg institutions and thecondition of specific requirements for large enterprises of work permits in the field of radiological work that issued by the Council. Article III: the functions and duties of officers in the prevention of radiological oversee the development of radiation protection programmes in the planning stages, construction and preparing the rules of local labour and what it lead of such tasks.Article IV: radiation protection officers powers: to modify and approve the programme of prevention and radiation safety at the company, stop any unsafe steps, amend the steps of the usage, operation of materials, devices and so on

Ergonomics in the office environment

Science.gov (United States)

Courtney, Theodore K.

1993-01-01

Perhaps the four most popular 'ergonomic' office culprits are: (1) the computer or visual display terminal (VDT); (2) the office chair; (3) the workstation; and (4) other automated equipment such as the facsimile machine, photocopier, etc. Among the ergonomics issues in the office environment are visual fatigue, musculoskeletal disorders, and radiation/electromagnetic (VLF,ELF) field exposure from VDT's. We address each of these in turn and then review some regulatory considerations regarding such stressors in the office and general industrial environment.

7 CFR 2003.14 - Field Offices.

Science.gov (United States)

2010-01-01

...) ADMINISTRATIVE REGULATIONS ORGANIZATION Functional Organization of the Rural Development Mission Area § 2003.14... Office Program Directors. State Directors may organizationally structure their offices based on the... tier program delivery structure. In a three tier system, Local offices report to an Area office, that...

75 FR 55786 - Office of Special Education Programs, Office of Special Education and Rehabilitative Services...

Science.gov (United States)

2010-09-14

... DEPARTMENT OF EDUCATION Office of Special Education Programs, Office of Special Education and Rehabilitative Services, Department of Education; Notice of Final Extension of Project Period and Waiver for the... Transition Technical Assistance Center (NSTTAC). Currently, the Office of Special Education Programs (OSEP...

No association between temperature and deaths from cardiovascular and cerebrovascular diseases during the cold season in Astana, Kazakhstan – the second coldest capital in the world

Directory of Open Access Journals (Sweden)

Andrej M. Grjibovski

2012-12-01

Full Text Available Background. Several European and North American studies have reported associations between cold temperatures and mortality from diseases of the circulatory system. However, the effects of cold vary between the settings warranting further research in other parts of the world. Objectives. To study associations between temperature and mortality from selected diseases of circulatory system in Astana, Kazakhstan – the second coldest capital in the world. Methods. Daily counts of deaths from hypertensive diseases (ICD-10 codes: I10–I15, ischemic heart disease (I20–I25 and cerebrovascular diseases (I60–I69 among adults 18 years and older in Astana, Kazakhstan, during cold periods (October–March in 2000–2001 and 2006–2010 were collected from the City Registry Office. Associations between mortality and mean apparent temperature and minimum apparent temperature (average for lags 0–15 were studied using Poisson regression controlling for barometric pressure (average for lags 0–3, wind speed and effects of month, year, weekends and holidays. Analyses were repeated using mean and minimum temperatures. Results. Overall, there were 320, 4468 and 2364 deaths from hypertensive disorders, ischemic heart disease and cerebrovascular diseases, respectively. No significant associations between either mean, mean apparent, minimum or minimum apparent temperatures were found for any of the studied outcomes. Conclusions. Contrary to the European findings, we did not find inverse associations between apparent temperatures and mortality from cardiovascular or cerebrovascular causes. Factors behind the lack of association may be similar to those in urban settings in Siberia, that is, centrally heated houses and a culture of wearing large volumes of winter clothes outdoors. Further research on the sensitivity of the population in Kazakhstan to climatic factors and its adaptive capacity is warranted.

No association between temperature and deaths from cardiovascular and cerebrovascular diseases during the cold season in Astana, Kazakhstan – the second coldest capital in the world

Science.gov (United States)

Grjibovski, Andrej M.; Nurgaliyeva, Nassikhat; Kosbayeva, Aliya; Menne, Bettina

2012-01-01

Background Several European and North American studies have reported associations between cold temperatures and mortality from diseases of the circulatory system. However, the effects of cold vary between the settings warranting further research in other parts of the world. Objectives To study associations between temperature and mortality from selected diseases of circulatory system in Astana, Kazakhstan – the second coldest capital in the world. Methods Daily counts of deaths from hypertensive diseases (ICD-10 codes: I10–I15), ischemic heart disease (I20–I25) and cerebrovascular diseases (I60–I69) among adults 18 years and older in Astana, Kazakhstan, during cold periods (October–March) in 2000–2001 and 2006–2010 were collected from the City Registry Office. Associations between mortality and mean apparent temperature and minimum apparent temperature (average for lags 0–15) were studied using Poisson regression controlling for barometric pressure (average for lags 0–3), wind speed and effects of month, year, weekends and holidays. Analyses were repeated using mean and minimum temperatures. Results Overall, there were 320, 4468 and 2364 deaths from hypertensive disorders, ischemic heart disease and cerebrovascular diseases, respectively. No significant associations between either mean, mean apparent, minimum or minimum apparent temperatures were found for any of the studied outcomes. Conclusions Contrary to the European findings, we did not find inverse associations between apparent temperatures and mortality from cardiovascular or cerebrovascular causes. Factors behind the lack of association may be similar to those in urban settings in Siberia, that is, centrally heated houses and a culture of wearing large volumes of winter clothes outdoors. Further research on the sensitivity of the population in Kazakhstan to climatic factors and its adaptive capacity is warranted. PMID:23256090

Owen Barwell - Chief Financial Officer | NREL

Science.gov (United States)

Owen Barwell - Chief Financial Officer Owen Barwell - Chief Financial Officer A photo of Owen , analysis, and management. He previously served as the Acting Chief Financial Officer and Deputy Chief Financial Officer of the U.S. Department of Energy (DOE), where he was directly responsible for DOE's

77 FR 3506 - Copyright Office Fees

Science.gov (United States)

2012-01-24

... creativity. The copyright law itself is designed to promote and protect authorship and this includes... LIBRARY OF CONGRESS Copyright Office [Docket No. 2012-1] Copyright Office Fees AGENCY: Copyright Office, Library of Congress. ACTION: Notice of Inquiry; Fees. SUMMARY: The U.S. Copyright Office is in...

Office design's impact on sick leave rates.

Science.gov (United States)

Bodin Danielsson, Christina; Chungkham, Holendro Singh; Wulff, Cornelia; Westerlund, Hugo

2014-01-01

The effect of office type on sickness absence among office employees was studied prospectively in 1852 employees working in (1) cell-offices; (2) shared-room offices; (3) small, (4) medium-sized and (5) large open-plan offices; (6) flex-offices and (7) combi-offices. Sick leaves were self-reported two years later as number of (a) short and (b) long (medically certified) sick leave spells as well as (c) total number of sick leave days. Multivariate logistic regression analysis was used, with adjustment for background factors. A significant excess risk for sickness absence was found only in terms of short sick leave spells in the three open-plan offices. In the gender separate analysis, this remained for women, whereas men had a significantly increased risk in flex-offices. For long sick leave spells, a significantly higher risk was found among women in large open-plan offices and for total number of sick days among men in flex-offices. A prospective study of the office environment's effect on employees is motivated by the high rates of sick leaves in the workforce. The results indicate differences between office types, depending on the number of people sharing workspace and the opportunity to exert personal control as influenced by the features that define the office types.

Gender differences in public office workers' satisfaction, subjective symptoms and musculoskeletal complaints in workplace and office environments.

Science.gov (United States)

Lee, Sangbok; Park, Myoung Hwan; Jeong, Byung Yong

2018-06-01

This study investigates differences between male and female public office workers' satisfaction levels, sick building syndrome (SBS) symptoms and musculoskeletal disorder (MSD) complaints in workplace and office environments. Questionnaire surveys were performed in 30 offices from 15 public institutions. Male and female workers of the same age were coupled and selected from each office, gathering a total of 120 male and 120 female subjects. The results show that differences exist between genders in noise and lighting satisfaction levels, SBS-related symptoms (eye, nose, skin) and MSD complaints of hand/wrist/finger, while there is no difference in overall satisfaction level of office environments. The study also suggests that office design for public office workers should take into account gender differences in preventing MSDs and also SBS. The findings of this study are expected to serve as basic data for designing effective public office environments.

75 FR 55785 - Office of Special Education Programs, Office of Special Education and Rehabilitative Services...

Science.gov (United States)

2010-09-14

... DEPARTMENT OF EDUCATION Office of Special Education Programs, Office of Special Education and Rehabilitative Services, Department of Education; Notice of Final Extension of Project Period and Waiver for the... this award, the Office of Special Education Programs (OSEP) funds NCEO to address national, State, and...

NOAA Workforce Management Office

Science.gov (United States)

Management Fellows (PMFs) Program Coordination Office - Leadership Development Program (PCO-LDP) Employee (NRAP) Presidential Management Fellows (PMFs) Program Coordination Office - Leadership Development ) NOAA Leadership Seminar (NLS) NOAA Rotational Assignment Program (NRAP) Presidential Management Fellows

HUD's Local Office Directory

Data.gov (United States)

Department of Housing and Urban Development — HUD is organized in 10 Regions. Each Region is managed by a Regional Administrator, who also oversees the Regional Office. Each Field Office within a Region is...

12 CFR 561.39 - Principal office.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Principal office. 561.39 Section 561.39 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY DEFINITIONS FOR REGULATIONS AFFECTING ALL SAVINGS ASSOCIATIONS § 561.39 Principal office. The term principal office means the home...

48 CFR 908.7103 - Office machines.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Office machines. 908.7103... PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized contractors shall be in accordance with FPMR...

Protective action guides: theory and application lessons from the Three Mile Island Accident

International Nuclear Information System (INIS)

Shleien, B.

1980-01-01

Protective action guides define the projected dose commitment to individuals in the general population that warrants protective action following the release of radioactive materials. Protective action would be warranted if the expected individual dose reduction is not offset by negative social, economic or health effects. Proposed or recommended protective action guides are available for the accidental radioactive contamination of human food and animal feeds, contamination of drinking water, evacuation and shelter, and administration of thyroid-blocking agents in a radiation emergency. This presentation discusses 1) the bases and status of the guides, 2) their interpretation and use, and 3) problems that were encountered in their interpretation. The available protective action guides proved effective during a nuclear accident emergency in protecting the public's health, in preventing unnecessary economic loss, and in diminishing social disruption. (author)

Prototype Effect and the Persuasiveness of Generalizations.

Science.gov (United States)

Dahlman, Christian; Sarwar, Farhan; Bååth, Rasmus; Wahlberg, Lena; Sikström, Sverker

An argument that makes use of a generalization activates the prototype for the category used in the generalization. We conducted two experiments that investigated how the activation of the prototype affects the persuasiveness of the argument. The results of the experiments suggest that the features of the prototype overshadow and partly overwrite the actual facts of the case. The case is, to some extent, judged as if it had the features of the prototype instead of the features it actually has. This prototype effect increases the persuasiveness of the argument in situations where the audience finds the judgment more warranted for the prototype than for the actual case (positive prototype effect), but decreases persuasiveness in situations where the audience finds the judgment less warranted for the prototype than for the actual case (negative prototype effect).

Mail Office

CERN Multimedia

GS Department

2009-01-01

The Mail Office wishes to remind users that the CERN mail service is exclusively reserved for official CERN mail. All external official mail must be sent to the Mail Office in an unstamped envelope on which your name and Department must be clearly indicated below the official CERN address (see example) to help us to find you in the event that it cannot be delivered. If you wish to send private mail from the CERN site you must use the post offices at Meyrin (63-R-011) or Prévessin (866-R-C02). Please use "PRIORITY" envelopes only in the case of urgent mail. Any mail containing merchandise (i.e. anything other than documents) must be sent using an EDH shipping request form. INTERNAL MAIL Please remember to include the recipient’s MAILBOX number on the internal mail envelopes, either in the relevant box (new envelopes) or next to the name (old envelopes). This information, which can be found in the CERN PHONEBOOK, simplifies our t...

24 CFR 300.9 - Office.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Office. 300.9 Section 300.9 Housing... NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.9 Office. The Association directs its operations from its office located at 451 Seventh Street, SW., Washington DC 20410. ...

7 CFR 7.17 - Dual office.

Science.gov (United States)

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Dual office. 7.17 Section 7.17 Agriculture Office of... STATE, COUNTY AND COMMUNITY COMMITTEES § 7.17 Dual office. (a) County committee membership. A member of... any other county office employee. (b) Community committee membership. A member of the community...

31 CFR 50.2 - Responsible office.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Responsible office. 50.2 Section 50.2 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM General Provisions § 50.2 Responsible office. The office responsible for the administration of the...

77 FR 31161 - Designation of Officers of the Millennium Challenge Corporation To Act as Chief Executive Officer...

Science.gov (United States)

2012-05-25

... of May 21, 2012 Designation of Officers of the Millennium Challenge Corporation To Act as Chief Executive Officer of the Millennium Challenge Corporation Memorandum for the Chief Executive Officer of the... following officers of the Millennium Challenge Corporation (MCC), in the order listed, shall act as and...

28 CFR 90.19 - State office.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false State office. 90.19 Section 90.19...¢ Training ⢠Officers ⢠Prosecutors) Violence Against Women Formula Grant Program § 90.19 State office. (a... office for the purposes of: (1) Certifying qualifications for funding under this subpart B; (2...

Contraindications to Athletic Participation. Cardiac, Respiratory, and Central Nervous System Conditions.

Science.gov (United States)

Moeller, James L.

1996-01-01

Discusses contraindications to athletic participation, examining the cardiac, respiratory, and central nervous system conditions that warrant activity disqualification. Provides guidelines about when it is safe for individuals to participate, and discusses the physician's responsibility. (SM)

Be Vigilant on Financial Statements.

Science.gov (United States)

Freed, DeBow

2002-01-01

Highlights areas on university's financial statements that warrant careful review by trustees and suggests ways they can check to see whether an institution's financial statements are clear and valid indicators of its financial status. (EV)

GC–MS analysis of bioactive compounds present in different extracts of an endemic plant Broussonetia luzonica (Blanco (Moraceae leaves

Directory of Open Access Journals (Sweden)

Franelyne Pataueg Casuga

2016-11-01

Conclusions: The three extracts possess major bioactive compounds that were identified and characterized spectroscopically. Thus, identification of different biologically active compounds in the extracts of B. luzonica leaves warrants further biological and pharmacological studies.

Mindfulness intervention in the management of chronic pain and psychological comorbidity: A meta-analysis

Directory of Open Access Journals (Sweden)

Yan Song

2014-06-01

Conclusion: There is insufficient evidence that mindfulness intervention relieves pain intensity. However, it improves depression and trait anxiety in patients with chronic pain. Further research in larger, properly powered, and better-designed studies is warranted.

Intravenous contrast-enhanced cone beam computed tomography (IVCBCT of intrahepatic tumors and vessels

Directory of Open Access Journals (Sweden)

Cynthia L. Eccles, BSc

2016-01-01

Conclusions: Intravenous-CBCT may enhance the visibility of hepatic vessels and tumor in CBCT scans obtained during breath hold. Optimization of IV contrast timing and reduction of artifacts to improve tumor visualization warrant further investigation.

Fecal Carriage of Extended‑spectrum Beta‑lactamase and AmpC ...

African Journals Online (AJOL)

sulfamethoxazole, and carbapenems were 31.2%, 33.3%, and 0%, respectively. Conclusion: The relative high prevalence of fecal carriage of ESBL‑producing bacteria in community warrants further study in this field including developing policies ...

Global instabilities and transient growth in Blasius boundary-layer ...

Indian Academy of Sciences (India)

boundary-layer flow warrants attention. .... double prime indicates a dummy variable, while R and S respectively denote integration in the ..... (labelled) but it also features an unstable structural mode labelled S that ..... theory and experiment.

Utility of the Robson Ten Group Classification System to determine ...

African Journals Online (AJOL)

... to the high rates and for which focused interventions may bring about change. ... single cephalic term pregnancy; spontaneous labour) warrants the most attention. Applying stricter criteria and due diligence in decision-making for primary CS ...

The efficacy and nephrotoxicity associated with colistin use in an intensive care unit in Vietnam: Use of colistin in a population of lower body weight

Directory of Open Access Journals (Sweden)

Nguyen Gia Binh

2015-06-01

Conclusion: A personalized dosing protocol of colistin was effective, with low nephrotoxicity, among critically ill Vietnamese patients with low body weight. Further studies are warranted for assessing the efficacy and toxicity in a larger cohort.

The effect of pomegranate extract on survival and peritoneal bacterial load in cecal ligation and perforation model of sepsis in rats

Directory of Open Access Journals (Sweden)

Sanaz Tavasoli

2014-01-01

Conclusions: Our study demonstrates for the first time that pomegranate extract could increase mortality rate via increasing peritoneal cavity bacterial load, in CLP sepsis model. More studies to assess mechanisms of this effect are warranted.

Office of the Chief Financial Officer Strategic Plan2008-2012

Energy Technology Data Exchange (ETDEWEB)

Various

2007-11-19

This is an update to the Office of the Chief Financial Officer's (OCFO's) multi-year strategy to continue to build a highly effective, efficient and compliant financial and business approach to support the scientific mission of Lawrence Berkeley National Laboratory (LBNL). The guiding principles of this strategy are to provide the greatest capability for the least cost while continually raising the standards of professional financial management in service to the LBNL science mission.

39 CFR 2.3 - Offices.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Offices. 2.3 Section 2.3 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE GENERAL AND TECHNICAL PROVISIONS (ARTICLE II) § 2.3 Offices. The principal office of the Postal Service is located in Washington, DC, with...

Natural phenomena evaluation of the Department of Energy-field office Oak Ridge office buildings

International Nuclear Information System (INIS)

Rucker, R.W.; Fricke, K.E.; Hunt, R.J.

1991-01-01

The Department of Energy - Field Office Oak Ridge (DOE-OR) is performing natural phenomena evaluations of existing office buildings located in the city of Oak Ridge, Tennessee. The natural phenomena considered are earthquake, wind, and flood. The evaluations are being performed to determine if the facilities are in compliance with DOE General Design Criteria 6430.IA. This paper presents results of the evaluations for three of the office buildings

77 FR 16850 - Notice of Reclassification of One Investigative Field Office to Regional Office: Denver, CO

Science.gov (United States)

2012-03-22

...This notice advises the public that the HUD/OIG Office of Investigation plans to reclassify its Denver, Colorado field office as a regional office. The planned reorganization is intended to: 1. Improve the alignment of limited investigative resources, to promote more efficient responses to HUD or Congressional requests involving critical program issues; 2. Redeploy resources to prevent and detect fraud in new program delivery of CPD, FHA and other HUD programs; and 3. Improve management control and effectiveness, and reduce travel costs of management by reducing region size. 4. Return to the traditional Regional alignment of HUD OIG Regional offices and HUD Regional offices.

Using Office 365 with Windows 8

CERN Document Server

Wilson, Kevin

2014-01-01

Learn Office the easy way, no jargon. Clear, concise and to the point... Using Microsoft Office 365, is the essential step by step guide to getting the most out of the traditional Microsoft Office applications (not SharePoint), providing a complete resource for both the beginner and the enthusiast.Techniques are illustrated step-by-step using photography and screen prints throughout, together with concise, easy to follow text from an established expert in the field, provide a comprehensive guide to office applications. Whether you are new to Microsoft Office, an experienced user or studying a

Bleaching and secondary threats on the corals of Palk Bay: A survey and Proactive conservation needs

Digital Repository Service at National Institute of Oceanography (India)

Ravindran, J.; Kannapiran, E.; Manikandan, B.; ManiMurali, R.; Joseph, A.

and altered environmental conditions warrant the proactive conservation approach guided by scientific principles. Current conservation methods in India offers physical protection to corals by entry restriction and a ban on collection of corals under wild life...

Piloting a mobile health intervention to increase physical activity for adolescents with ADHD

Directory of Open Access Journals (Sweden)

Erin Schoenfelder

2017-06-01

Results indicate that this mHealth intervention is engaging and promising for increasing PA among adolescents with ADHD, and warrant further study. Implications for improving ADHD symptoms and overall functioning for this undertreated population are discussed.

Crowning corals

Digital Repository Service at National Institute of Oceanography (India)

Raghukumar, C.

and build-awareness about the rich, diverse biological resources is warranted and a plea is made to manage the sewage, oil and thermal pollution to help preserve the biodiversity of coral and associated flora and fauna....

Changing Livelihoods in the Coastal Zone of the Western Indian ...

African Journals Online (AJOL)

Western Indian Ocean Journal of Marine Science ... of WIO-East African coastal life warrants both single- and ... Perspectives are needed of both natural and ... This work is licensed under a Creative Commons Attribution 3.0 License.

Gastroesophageal Reflux Disease and Sleep Quality in a Chinese Population

Directory of Open Access Journals (Sweden)

Mei-Jyh Chen

2009-01-01

Conclusion: The present study highlights the adverse effect of gastroesophageal reflux on sleep, even in the absence of reflux symptoms. This finding has therapeutic implications in patients with silent erosive disease, and future trials are warranted.

Prenatal diagnosis of familial transmission of 17q12 microduplication associated with no apparent phenotypic abnormality

Directory of Open Access Journals (Sweden)

Chih-Ping Chen

2016-12-01

Conclusion: The 17q12 microduplication may present with variable phenotypes including no apparent phenotypic abnormality in familial cases. However, neuropsychiatry assessment and monitoring should be warranted in childhood and through adulthood under such a circumstance.

Postpolypectomy lower GI bleeding: descriptive analysis

NARCIS (Netherlands)

Sorbi, D.; Norton, I.; Conio, M.; Balm, R.; Zinsmeister, A.; Gostout, C. J.

2000-01-01

BACKGROUND: Postpolypectomy hemorrhage may warrant intensive care monitoring, transfusions, and surgery. We sought factors predicting significant bleeding requiring blood transfusion and the benefits of critical care monitoring. METHODS: Patients with postpolypectomy bleeding between April 1989 and

Enrichment and Characterization of an Autotrophic Ammonia-Oxidizing Archaeon of Mesophilic Crenarchaeal Group I.1a from an Agricultural Soil

NARCIS (Netherlands)

Jung, M.Y.; Park, S.J.; Min, D.; Kim, J.S.; Rijpstra, W.I.C.; Sinninghe Damsté, J.S.; Kim, G.J.; Madsen, E.L.; Rhee, S.K.

2011-01-01

Soil nitrification is an important process for agricultural productivity and environmental pollution. Though one cultivated representative of ammonia-oxidizing Archaea from soil has been described, additional representatives warrant characterization. We describe an ammonia-oxidizing archaeon (strain

Changes in Outcome and Complication Rates of Very-low-birth-weight Infants in One Tertiary Center in Southern Taiwan Between 2003 and 2010

Directory of Open Access Journals (Sweden)

Shen-Dar Chen

2014-08-01

Conclusion: Periodic evaluation of the mortality and morbidity of preterm infants can help to understand the changes and trends of our neonatal care. Further study using the national dataset to provide more representative information is warranted.

Circumscribed Lipoatrophy of the Chin after Tooth Extraction

Directory of Open Access Journals (Sweden)

Uwe Wollina

2017-07-01

Full Text Available We describe the rare occurrence of circumscribed facial lipoatrophy after tooth extraction. Correction by minimal invasive esthetic techniques such as soft tissue fillers or autologous fat transfer is possible but was not warranted.

Longitudinal changes in microstructural white matter metrics in Alzheimer's disease

Directory of Open Access Journals (Sweden)

Chantel D. Mayo

2017-01-01

Conclusion: The current results indicate that sensitivity to white matter microstructure is a promising avenue for AD biomarker research. Additional longitudinal studies on both white and grey matter are warranted to further evaluate potential clinical utility.

GTP-z. Good pharmacotherapy practice for hospital pharmacies

NARCIS (Netherlands)

Van den Bemt, P.M.L.A.; Van Roon, E.N.; Hekster, Y.A.; Brouwers, J.R.B.J.

2001-01-01

Apart from their traditional responsibilities (aimed at dispensing good products), Dutch hospital pharmacists are increasingly involved in patient-oriented responsibilities. Although the Dutch Hospital Pharmacy Standard (Ziekenhuis Apotheek Norm) warrants certain procedures for drug use evaluation,

Promoter Analysis Reveals Globally Differential Regulation of Human Long Non-Coding RNA and Protein-Coding Genes

KAUST Repository

Alam, Tanvir; Medvedeva, Yulia A.; Jia, Hui; Brown, James B.; Lipovich, Leonard; Bajic, Vladimir B.

2014-01-01

raise the possibility that, given the historical reliance on protein-coding gene catalogs to define the chromatin states of active promoters, a revision of these chromatin signature profiles to incorporate expressed lncRNA genes is warranted

Regression of Some High-risk Features of Age-related Macular Degeneration (AMD in Patients Receiving Intensive Statin Treatment

Directory of Open Access Journals (Sweden)

Demetrios G. Vavvas

2016-03-01

Conclusions: High-dose statins may result in resolution of drusenoid pigment epithelial detachments (PEDs and improvement in VA, without atrophy or neovascularization in a high-risk subgroup of AMD patients. Confirmation from larger studies is warranted.

Environmental & Psychosocial Contributors to Learning Disparities

Science.gov (United States)

Purpose: Studies suggest early traffic-related pollution exposures (TRPEs) adversely impact cognitive development (COGDEV). Since racial differences do not explain the widening achievement gap, determining TRPE contributions is warranted. Study objectives were to (1) assess the...

Internet-based cognitive behavioral therapy for depression and anxiety in Parkinson's disease — A pilot study

Directory of Open Access Journals (Sweden)

Martin Kraepelien

2015-03-01

Conclusions: The results suggest that ICBT could be a feasible way to alleviate depression and anxiety in PD. However, a somewhat simplified treatment and different ways to provide support to enhance adherence and outcome are warranted.

Metastatic papillary carcinoma of the thyroid in a patient previously ...

African Journals Online (AJOL)

Keywords: Graves' disease, papillary thyroid carcinoma, radioactive iodine. Résumé. Accessoire de ... une cause de préoccupation et de controverse pour ceux qui s'occupent d'eux. ... remained thyrotoxic warranting administration of three ...

Intensified tuberculosis case finding among hiv-infected individuals

African Journals Online (AJOL)

2011-10-02

burden ... active TB (and in need of treatment) or being free of TB disease (and warranting ... following symptoms – current cough, fever, weight loss or night sweats (CFWS) .... and stand-alone HIV testing services. The WHO ...

7 CFR 2.20 - Under Secretary for Natural Resources and Environment.

Science.gov (United States)

2010-01-01

... Comp., p. 351, and the National Contingency Plan, 40 CFR part 300. (iii) Represent USDA in contacts... to believe are being committed in that employee's presence or view, or for a felony with a warrant or...

Patients′ awareness of antibiotic use in Bahraini health centers and community pharmacies

Directory of Open Access Journals (Sweden)

Sayed Mahmood Alqallaf

2015-01-01

Conclusion: Bahraini patients are mostly aware of 12 antibiotic aspects despite some misconceptions. The public awareness and their expectations warrant further studies on a large scale to understand their self-medication and demand for antibiotic prescriptions.

Border Security and Military Support: Legal Authorizations and Restrictions

National Research Council Canada - National Science Library

Vina, Stephen R

2006-01-01

... enforcement unless explicitly authorized. There are alternative legal authorities for deploying the National Guard, and the precise scope of permitted activities and funds may vary with the authority exercised. This report will be updated as warranted.

Is the Office Hour Obsolete?

Science.gov (United States)

Behrens, Susan

2013-01-01

A colleague can't make a coffee date at a time the author proposes because it would conflict with his office hour. No student has actually made an appointment with him during the hour, but he is committed to being in his office as promised in case someone drops by. The author's reaction to her colleague's faithfulness to his posted office hour…

76 FR 65511 - Office of Governmentwide Policy; Office of Federal High-Performance Green Buildings; the Green...

Science.gov (United States)

2011-10-21

... Governmentwide Policy; Office of Federal High- Performance Green Buildings; the Green Building Advisory Committee... meeting of the Green Building Advisory Committee Meeting (the Committee). The meeting is open to the..., Office of Federal High-Performance Green Buildings, Office of Governmentwide Policy, General Services...

Office 2013 digital classroom

CERN Document Server

Holland, Walter

2013-01-01

This complete training package makes learning the new Office 2013 even easier! Featuring both a video training DVD and a full-color book, this training package is like having your own personal instructor guiding you through each lesson of learning Office 2013, all while you work at your own pace. The self-paced lessons allow you to discover the new features and capabilities of the new Office suite. Each lesson includes step-by-step instructions and lesson files, and provides valuable video tutorials that complement what you're learning and clearly demonstrate how to do tasks. This essential

78 FR 25277 - Office of the Secretary; Office of the Assistant Secretary for Preparedness and Response...

Science.gov (United States)

2013-04-30

... Office of Preparedness and Emergency Operations (ANC), establish five Divisions under the Office of Preparedness and Emergency Operations (ANC), and rename one existing Division. The changes are as follows. I..., Paragraph C, Office of Preparedness and Emergency Operations (ANC): a. Replace all references to the...

Association between erectile dysfunction and chronic periodontitis: A clinical study

Directory of Open Access Journals (Sweden)

Ranjit Singh Uppal

2014-01-01

Conclusion: It may be concluded that chronic periodontitis and ED are associated with each other. However, further large scale studies with confounder analysis and longitudinal follow-up are warranted to explore the link between these two diseases.

Spritzer: For diagnostic cytopathology

Directory of Open Access Journals (Sweden)

Rashmi Metgud

2017-01-01

Conclusion: The one-step LG cocktail is easy, very cost-effective, less time-consuming with less infrastructural support as compared to PAP stain; however, it warrants further evaluation for screening of oral cancer as a potential aid.

Radiofrequency Ablation versus Liver Resection for Colorectal Cancer Liver Metastasis: An Updated Systematic Review and Meta-analysis

Directory of Open Access Journals (Sweden)

Yue Han

2016-01-01

Conclusions: Patients with CRCLM gained much more survival benefits from LR than that from RFA. RFA rendered lower rates of morbidities. More well-designed randomized controlled trails comparing the therapeutic value of LR and RFA are warranted.

Change in left ventricular systolic function in patients with ST elevation myocardial infarction: Evidence for smoker's paradox or pseudo-paradox?

Directory of Open Access Journals (Sweden)

Burak Acar

2016-11-01

Conclusion: True or persistent ‘smoker's paradox’ does not appear to be relevant among STEMI patients undergoing p-PCI. The ‘smoker's paradox’ is in fact a pseudo-paradox. Further studies with larger numbers may be warranted.

Scientific Research in Education: A Socratic Dialogue

Science.gov (United States)

Boody, Robert M.

2011-01-01

Socrates and Admetus discuss the value of scientific research in education. They conclude that although RCTs have their place, they are not a panacea for education, and that the push for them by NCLB is not warranted.

31 CFR 103.60 - Enforcement authority with respect to transportation of currency or monetary instruments.

Science.gov (United States)

2010-07-01

... respect to which a report required under § 103.23 has not been filed or contains material omissions or misstatements, he may apply to any court of competent jurisdiction for a search warrant. Upon a showing of...

Highway construction work zone safety performance and improvement in Louisiana : research project capsule.

Science.gov (United States)

2016-08-01

While the number of : crashes in Louisiana : construction work zones : has decreased in recent : years, the total count of : work zone crashes is still : significant, warranting : research into how to reduce : crashes. An assessment : of risk factors...

Potentially avoidable peripartum hysterectomies in Denmark

DEFF Research Database (Denmark)

Colmorn, Lotte Berdiin; Krebs, Lone; Langhoff-Roos, Jens

2016-01-01

to minimize the number of unnecessary peripartum hysterectomies, obstetricians and anesthesiologists should investigate individual cases by structured clinical audit, and disseminate and discuss the results for educational purposes. An international collaboration is warranted to strengthen our recommendations...

Prostate carcinoma mimicking a sphenoid wing meningioma

Directory of Open Access Journals (Sweden)

Lucas H. Bradley

2015-01-01

Conclusion: We conclude that dural-based metastatic lesions may mimic meningiomas, warranting thorough pre-operative work-up to exclude the possibility of metastasis. In certain cases, identification of widespread disease might preclude surgery and favor palliation, instead.

Porcine Small Intestinal Submucosa Mesh for Treatment of Pelvic Organ Prolapsed

Directory of Open Access Journals (Sweden)

Ting-Ting Cao

2016-01-01

Conclusions: QOL and the degree of subjective satisfaction were significantly improved postoperatively. Anterior repair deserves more attention because of the higher recurrence rate. The long-term follow-up of the patient is warranted to draw firm conclusion.

Efficacy and toxicity of rectal cancer reirradiation using IMRT for patients who have received prior pelvic radiation therapy

Directory of Open Access Journals (Sweden)

Fady F. Youssef, MS

2016-04-01

Conclusions: Rectal cancer reirradiation using IMRT is well-tolerated in the setting of prior pelvic radiation therapy. Given significant risk of local progression, further dose escalation may be warranted for patients with life expectancy exceeding 1 year.

Google Sets, Google Suggest, and Google Search History: Three More Tools for the Reference Librarian's Bag of Tricks

OpenAIRE

Cirasella, Jill

2008-01-01

This article examines the features, quirks, and uses of Google Sets, Google Suggest, and Google Search History and argues that these three lesser-known Google tools warrant inclusion in the resourceful reference librarian’s bag of tricks.

Cinacalcet hydrochloride for the treatment of hyperparathyroidism

NARCIS (Netherlands)

Verheyen, N.; Pilz, S.; Eller, K.; Kienreich, K.; Fahrleitner-Pammer, A.; Pieske, B.; Ritz, E.; Tomaschitz, A.

2013-01-01

Introduction: Effective therapeutic strategies are warranted to reduce the burden of parathyroid hormone excess related morbidity and mortality. The calcimimetic agent cinacalcet hydrochloride is a promising treatment strategy in hyperparathyroidism. Areas covered: This review provides an overview

Office type's association to employees' welfare: Three studies.

Science.gov (United States)

Danielsson, Christina Bodin

2016-08-12

The workplace is important for employees' daily life and well-being. This article investigates exploratory the office design's role for employees' welfare from different perspectives. By comparing different studies of the office, type's influence on different factors of employees' welfare the aim is to see if any common patterns exist in office design's impact. The three included studies investigate office type's association with employees' welfare by measuring its influence on: a) perception of leadership, b) sick leave, and c) job satisfaction.The sample consists of office employees from a large, national representative work environment survey that work in one of the seven identified office types in contemporary office design: (1) cell-offices; (2) shared-room offices; (3) small, (4) medium-sized and (5) large open-plan offices; (6) flex-offices and (7) combi-offices. Statistical method used is multivariate logistic and linear regression analysis with adjustment for background factors. Overall results show that shared-room office, traditional open plan offices and flex-office stand out negatively, but to different degree(s) on the different outcomes measured. This explorative comparison of different studies finds a pattern of office types that repeatedly show indications of negative influence on employees' welfare, but further studies are needed to clarify this.

Office of Equal Opportunity Programs

Science.gov (United States)

Chin, Jennifer L.

2004-01-01

The NASA Glenn Office of Equal Opportunity Programs works to provide quality service for all programs and/or to assist the Center in becoming a model workplace. During the summer of 2004, I worked with Deborah Cotleur along with other staff members to create and modify customer satisfaction surveys. This office aims to assist in developing a model workplace by providing functions as a change agent to the center by serving as an advisor to management to ensure equity throughout the Center. In addition, the office serves as a mediator for the Center in addressing issues and concerns. Lastly, the office provides assistance to employees to enable attainment of personal and organizational goals. The Office of Equal Opportunities is a staff office which reports and provides advice to the Center Director and Executive Leadership, implements laws, regulations, and presidential executive orders, and provides center wide leadership and assistance to NASA GRC employees. Some of the major responsibilities of the office include working with the discrimination complaints program, special emphasis programs (advisory groups), management support, monitoring and evaluation, contract compliance, and community outreach. During my internship in this office, my main objective was to create four customer satisfaction surveys based on EO retreats, EO observances, EO advisory boards, and EO mediation/counseling. I created these surveys after conducting research on past events and surveys as well as similar survey research created and conducted by other NASA centers, program for EO Advisory group members, leadership training sessions for supervisors, preventing sexual harassment training sessions, and observance events. I also conducted research on the style and format from feedback surveys from the Marshall Equal Opportunity website, the Goddard website, and the main NASA website. Using the material from the Office of Equal Opportunity Programs at Glenn Research Center along with my

Automated Office Blood Pressure Measurement.

Science.gov (United States)

Myers, Martin G

2018-04-01

Manual blood pressure (BP) recorded in routine clinical practice is relatively inaccurate and associated with higher readings compared to BP measured in research studies in accordance with standardized measurement guidelines. The increase in routine office BP is the result of several factors, especially the presence of office staff, which tends to make patients nervous and also allows for conversation to occur. With the disappearance of the mercury sphygmomanometer because of environmental concerns, there is greater use of oscillometric BP recorders, both in the office setting and elsewhere. Although oscillometric devices may reduce some aspects of observer BP measurement error in the clinical setting, they are still associated with higher BP readings, known as white coat hypertension (for diagnosis) or white coat effect (with treated hypertension). Now that fully automated sphygmomanometers are available which are capable of recording several readings with the patient resting quietly, there is no longer any need to have office staff present when BP is being recorded. Such readings are called automated office blood pressure (AOBP) and they are both more accurate than conventional manual office BP and not associated with the white coat phenomena. AOBP readings are also similar to the awake ambulatory BP and home BP, both of which are relatively good predictors of cardiovascular risk. The available evidence suggests that AOBP should now replace manual or electronic office BP readings when screening patients for hypertension and also after antihypertensive drug therapy is initiated. Copyright © 2018. The Korean Society of Cardiology.

An athlete’s criminal liability towards spectators

Directory of Open Access Journals (Sweden)

mohammad nabipour

2017-10-01

Full Text Available Abstract:   Basically and according to clause of article 158 of the Islamic penal code, approved in 2013 (sporting activities and accidents resulting from it, if the reason of accidents do not violate the rules related to that sport and these regulation are not in conflict with religious rules there will be no criminal liability for the athlete. As it appears the athlete that will be exempted from any criminal offense when he has not violated the rules, however, if the athletes is offender whether the injured is opponent athlete or one of the spectators, the offending athletes will be liable for the penalty. In other words, what kind of criminal responsibility would be in these cases, if the act committed by him towards the spectator was deliberate (which would warrants retaliation or a psedudo_deliberate error (which would warrants the payment of atonement and also sanction punishment it means that imprisonment 1 to 3 years in case of victim death by the offending athlete according to article 616 in sanction law or vasted error (which would warrants prey for a loss by kinsmam the responsibility of the athlete will be different.But whether the athlete respect to all of the rules he will be completely exempted from the damage that he enters into the spectator or not, is the point of disagreement which this article seeks to ask the question.    

The effects of moderate heat stress and open-plan office noise distraction on office work

DEFF Research Database (Denmark)

Witterseh, Thomas; Wyon, David; Clausen, Geo

2002-01-01

Thirty subjects clothed for comfort at 22 deg.C performed simulated office work for 3 hours at 22/26/30 deg.C (7.4 g/kg dry air, i.e. 45/35/28 %RH) in quiet and recorded open-plan office noise (55 dBA) conditions. Warmth decreased perceived air quality (P......Thirty subjects clothed for comfort at 22 deg.C performed simulated office work for 3 hours at 22/26/30 deg.C (7.4 g/kg dry air, i.e. 45/35/28 %RH) in quiet and recorded open-plan office noise (55 dBA) conditions. Warmth decreased perceived air quality (P...

Optimizing lengths of confidence intervals: fourth-order efficiency in location models

NARCIS (Netherlands)

Klaassen, C.; Venetiaan, S.

2010-01-01

Under regularity conditions the maximum likelihood estimator of the location parameter in a location model is asymptotically efficient among translation equivariant estimators. Additional regularity conditions warrant third- and even fourth-order efficiency, in the sense that no translation

Metabolomic analysis reveals amino-acid responses to an oral glucose tolerance test in women with prior history of gestational diabetes mellitus

Directory of Open Access Journals (Sweden)

R. Bentley-Lewis, MD, MBA, MMSc

2014-06-01

Conclusions: Greater change in metabolite levels after a glucose challenge was significantly associated with a longer duration of breastfeeding and higher BMI. Further exploration of these preliminary observations and closer examination of the specific pathways implicated are warranted.

Unsupervised learning for robust bitcoin fraud detection

CSIR Research Space (South Africa)

Monamo, Patrick

2016-08-01

Full Text Available The rampant absorption of Bitcoin as a cryptographic currency, along with rising cybercrime activities, warrants utilization of anomaly detection to identify potential fraud. Anomaly detection plays a pivotal role in data mining since most outlying...

Assessing Cognitive Function in Older Adults Using a Videoconference Approach

Directory of Open Access Journals (Sweden)

Teresa Costa Castanho

2016-09-01

Interpretation: Findings indicate for the range of settings where videoconference approaches can be used, and for their applicability and acceptability, providing an alternative to current cognitive assessment methods. Continued validation studies and adaptation of neuropsychological instruments is warranted.

76 FR 34579 - Beneficial Ownership Reporting Requirements and Security-Based Swaps

Science.gov (United States)

2011-06-14

... beneficial ownership of the equity securities underlying derivative securities exercisable or convertible... exercise or conversion of any derivative security, whether or not presently exercisable.'' \\40\\ ``Derivative securities'' are ``any option, warrant, convertible security, stock appreciation right, or similar...

Electric Muscle Stimulation for Weaning from Mechanical Ventilation in Elder Patients with Severe Sepsis and Acute Respiratory Failure – A Pilot Study

Directory of Open Access Journals (Sweden)

Sheng-Yeh Shen

2017-03-01

Conclusion: EMS did not help critical-ill septic elderly to reduce the duration of mechanical ventilation in our pilot study. Further larger study is warranted with adequate study power and identical weaning strategy to test the EMS benefits.

Twelve weeks of dance exergaming in overweight and obese adolescent girls: Transfer effects on physical activity, screen time, and self-efficacy

Directory of Open Access Journals (Sweden)

Amanda E. Staiano

2017-03-01

Conclusion: Exergaming for 12 weeks was associated with positive impacts on adolescent girls' self-reported PA, television viewing, self-efficacy, and intrinsic motivation. Future research is warranted to leverage exergames as an enjoyable, motivating, and effective PA tool.

Serum platelet-derived growth factor and fibroblast growth factor in patients with benign and malignant ovarian tumors

DEFF Research Database (Denmark)

Madsen, Christine Vestergaard; Steffensen, Karina Dahl; Olsen, Dorte Aalund

2012-01-01

New biological markers with predictive or prognostic value are highly warranted in the treatment of ovarian cancer. The platelet-derived growth factor (PDGF) system and fibroblast growth factor (FGF) system are important components in tumor growth and angiogenesis....

Integrated prioritization method for active and passive highway-rail crossings.

Science.gov (United States)

2013-01-01

This two-year research project developed a prioritization system for highway-rail at-grade crossings that addressed the following major concerns: (1) warrants to identify low-volume, passive crossings with risk factors; (2) a broader priority index t...

The treatment of autonomic dysfunction in tetanus

African Journals Online (AJOL)

were considered too trivial to warrant medical attention.[6] Two toxins are produced ... There is selective inhibition of the inhibitory reflex in the central nervous system ... a short duration of action, but it may cause dose-dependent hypotension.

Detection of memory impairment in the general population: Screening by questionnaire and telephone compared to subsequent face-to-face assessment

NARCIS (Netherlands)

Uffelen, J.G.Z. van; Chin A Paw, M.J.M.; Klein, M.; Mechelen, W. van; Hopman-Rock, M.

2007-01-01

Background: Development of efficient methods for identifying subjects with Mild Cognitive Impairment (MCI) from the geneneral population is warranted, because these subjects represent an important group for (epidemiological) research purposes. Objectives: (1) To describe a two-step population

COMPARATIVE STUDY ON FISCAL-ADMINISTRATIVE SOLICITOR'S OFFICE AND FISCAL SOLICITOR'S OFFICE

OpenAIRE

OCTAVIA MARIA CILIBIU

2012-01-01

The fiscal-administrative solicitor's office represents the activity of solving litigations between tax payers and the fiscal administration, litigations whose purpose is to cancel totally or partially a fiscal administrative document, document considered by the tax payer harmful for his legitimate right or interest recognized by law. The fiscal solicitor's office represents the activity of solving litigations whose purpose is to cancel or correction of acts of enforcement of tax claims. Rese...

Low sustainability, poor governance, and other challenges encountered by grassroots non-governmental organizations targeting HIV prevention for men who have sex with men in China - a nation-wide study.

Science.gov (United States)

Lau, Joseph T F; Wang, Zixin; Kim, Yoona; Li, Jinghua; Gu, Jing; Mo, Phoenix K H; Wang, Xiaodong

2017-12-01

Grassroots non-governmental organizations (NGOs) played pivotal roles in HIV prevention among men who have sex with men (MSM) in China. Their governance and sustainability issues were under-studied. This nation-wide study surveyed leaders of 202 of the HIV related NGOs in China.58.4% of the leaders believed that their NGO would last for ≤5 years; which was negatively associated with perceived good relationship with CDC. 65.3% mentioned ≥3 non-sustainability issues; associated factors included perceived inadequacies in prevention skills, management skills, policy support, technical support, operational support, and CDC's support; a reverse association was found for frequent collaboration with organizations in China. 30.6% of the leaders mentioned ≥7 governance issues; a stepwise model found a positive association with having no office and negative associations with number of full-time staff and core volunteers. These problems would severely limit the effectiveness of HIV prevention among MSM. Related improvements and support are warranted.

Determining if disease management saves money: an introduction to meta-analysis.

Science.gov (United States)

Linden, Ariel; Adams, John L

2007-06-01

Disease management (DM) programmes have long been promoted as a major medical cost-saving mechanism, even though the scant research that exists on the topic has provided conflicting results. In a 2004 literature review, the Congressional Budget Office stated that 'there is insufficient evidence to conclude that disease management programs can generally reduce the overall cost of health care services'. To address this question more accurately, a meta-analysis was warranted. Meta-analysis is the quantitative technique used to pool the results of many studies on the same topic and summarize them statistically. This method is also quite suitable for individual DM firms to assess whether their programmes are effective at the aggregate level. This paper describes the elements of a rigorous meta-analytic process and discusses potential biases. A hypothetical DM organization is then evaluated with a specific emphasis on medical cost-savings, simulating a case in which different populations are served, evaluation methodologies are employed, and diseases are managed.

Public health strategies for Mäori.

Science.gov (United States)

Durie, M

2000-06-01

When the New Zealand Department of Public Health was established in 1900, Maöri health status was compromised to the extent that survival itself was threatened. The remarkable turnaround was unexpected and owes much to pioneer Maöri professionals, especially the first Maöri medical practitioner, Dr. Maui Pomare, who graduated in the United States in 1899. As "Medical Officer to the Maöris," and later as Minister of Health, he made major changes through a five-part strategy: recognizing Maöri community leaders as leaders in health, improving access to societal goods and services (especially housing and education), appealing to cultural practices that were linked to good health, wise use of political power, and developing a skilled Maori health workforce to complement community leadership. Although mental health disorders and lifestyle illnesses have largely replaced infectious diseases, malnutrition, and tuberculosis, Pomare's strategy has continuing relevance and warrants serious consideration as a model for health promotion.

Glaucomatous Optic Neuropathy Associated with Nocturnal Dip in Blood Pressure: Findings from the Maracaibo Aging Study.

Science.gov (United States)

Melgarejo, Jesús D; Lee, Joseph H; Petitto, Michele; Yépez, Juan B; Murati, Felipe A; Jin, Zhezhen; Chávez, Carlos A; Pirela, Rosa V; Calmón, Gustavo E; Lee, Winston; Johnson, Matthew P; Mena, Luis J; Al-Aswad, Lama A; Terwilliger, Joseph D; Allikmets, Rando; Maestre, Gladys E; De Moraes, C Gustavo

2018-01-05

To determine which nocturnal blood pressure (BP) parameters (low levels or extreme dipper status) are associated with an increased risk of glaucomatous damage in Hispanics. Observational cross-sectional study. A subset (n = 93) of the participants from the Maracaibo Aging Study (MAS) who met the study eligibility criteria were included. These participants, who were at least 40 years of age, had measurements for optical tomography coherence, visual field (VF) tests, 24-hour BP, office BP, and intraocular pressure 20% compared with daytime BP) were significant risk factors for glaucomatous damage (odds ratio, 19.78 and 5.55, respectively). In this population, the link between nocturnal BP and GON is determined by extreme dipping effects rather than low nocturnal BP levels alone. Further studies considering extreme decreases in nocturnal BP in individuals at high risk of glaucoma are warranted. Copyright © 2017 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

The 2010 calibration campaign for radon gas measuring instruments at PSI

International Nuclear Information System (INIS)

Butterweck, G.; Schuler, Ch.; Mayer, S.

2011-01-01

Twenty radon measurement services or the respective analytical laboratories participated in the 2010 Radon Intercomparison Exercise performed at the Reference Laboratory for Radon Gas Activity Concentration Measurements at the Paul Scherrer Institute (PSI) from August 27 th to August 31 st , 2010 on behalf of the Swiss Federal Office of Public Health (FOPH). Twelve of these laboratories were approved by the FOPH and their participation in the intercomparison exercise was a requirement to warrant quality of measurement. Radon gas dosemeters (track-etch, electronic and electret) and instruments (ionisation chambers) were exposed in the PSI Radon Chamber in a reference atmosphere with an average radon gas concentration of 595 Bq m -3 leading to a radon gas exposure of 57 kBq h m -3 . The exposure of 57 kBq h m -3 was close to the lower value of the measuring range defined in the Radon Measurement Ordinance ('Radon-Messmittelverordnung'). (authors)

Collateral findings during computed tomography scan for atrial fibrillation ablation: Let's take a look around.

Science.gov (United States)

Perna, Francesco; Casella, Michela; Narducci, Maria Lucia; Dello Russo, Antonio; Bencardino, Gianluigi; Pontone, Gianluca; Pelargonio, Gemma; Andreini, Daniele; Vitulano, Nicola; Pizzamiglio, Francesca; Conte, Edoardo; Crea, Filippo; Tondo, Claudio

2016-04-26

The growing number of atrial fibrillation catheter ablation procedures warranted the development of advanced cardiac mapping techniques, such as image integration between electroanatomical map and cardiac computed tomography. While scanning the chest before catheter ablation, it is frequent to detect cardiac and extracardiac collateral findings. Most collateral findings are promptly recognized as benign and do not require further attention. However, sometimes clinically relevant collateral findings are detected, which often warrant extra diagnostic examinations or even invasive procedure, and sometimes need to be followed-up over time. Even though reporting and further investigating collateral findings has not shown a clear survival benefit, almost all the working groups providing data on collateral findings reported some collateral findings eventually coming out to be malignancies, sometimes at an early stage. Therefore, there is currently no clear agreement about the right strategy to be followed.

Argumentation skill profile using “Toulmin Argumentation Pattern” analysis of high school student at Subang on topic hydrostatic pressure

Science.gov (United States)

Syerliana, L.; Muslim; Setiawan, W.

2018-05-01

This study aims to know profile of argumentation skill high school student at Kabupaten Subang. To achieve this goal, researcher conducted a descriptive study to analysis student test results of argumentation skill of 35 students XII SMAN. Data collection using argumentation test which has validation by expert and then it is analyzed using TAP (Toulmin Argumentation Pattern) which consist of some components such a data, claim, warrant, backing, and rebuttal on the topic of hydrostatic pressure. The method used in this research is descriptive method. The result of this research show the student’s scientific argumentation skill is still low, this is proven by 54% average claim score, 38% data, 29% warrant, 35% backing and 35% rebuttal. These findings will serve as a basis for further research on innovative learning models that can improve students’ argumentation skill.

Investigation on the actual energy consumption by office automation devices used in offices; Office ni okeru OA kiki no energy shohi jittai chosa

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-03-01

With an objective to further improve efficiency of power demand by office automation devices and suppress increase in the power demand, investigations were carried out on the actual power consumption by office automation devices, and discussions were given on energy saving effects in the office automation devices. In the investigations, measurements were conducted for small offices as the subject thereof with regard to electric power consumed by such presentation tools and their peripheral devices as personal computers, word processors, copying machines, facsimile machines, electronic whiteboards and overhead projectors. Power consumption particularly in a standby condition was also investigated. As a result of the investigations, the following characteristics were revealed: the number of office automation devices used to deal with the Energy Star is increasing rapidly; power consumption believed to have been reduced by the Energy Star transferring to lower power consumption is estimated to be 3% in average for personal computers, 26% for copying machines, and 68% for facsimile machines; and while facsimile machines are left in operating condition for 24 hours, their operation rate at night is very low, wherein there is a large room for saving energy in this time band. 65 figs., 21 tabs.

46 CFR 11.505 - Engineer officer structure.

Science.gov (United States)

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Engineer officer structure. 11.505 Section 11.505... OFFICER ENDORSEMENTS Professional Requirements for Engineer Officer § 11.505 Engineer officer structure. The following diagram illustrates the engineering endorsement structure including cross over points...

Personalized Hypertension Management Using Patient-Generated Health Data Integrated With Electronic Health Records (EMPOWER-H): Six-Month Pre-Post Study.

Science.gov (United States)

Lv, Nan; Xiao, Lan; Simmons, Martha L; Rosas, Lisa G; Chan, Albert; Entwistle, Martin

2017-09-19

EMPOWER-H (Engaging and Motivating Patients Online With Enhanced Resources-Hypertension) is a personalized-care model facilitating engagement in hypertension self-management utilizing an interactive Web-based disease management system integrated with the electronic health record. The model is designed to support timely patient-provider interaction by incorporating decision support technology to individualize care and provide personalized feedback for patients with chronic disease. Central to this process were patient-generated health data, including blood pressure (BP), weight, and lifestyle behaviors, which were uploaded using a smartphone. The aim of this study was to evaluate the program among patients within primary care already under management for hypertension and with uncontrolled BP. Using a 6-month pre-post design, outcome measures included office-measured and home-monitored BP, office-measured weight, intervention contacts, diet, physical activity, smoking, knowledge, and health-related quality of life. At 6 months, 55.9% of participants (N=149) achieved office BP goals (total intervention, behavioral, pharmaceutical contacts had significantly lower odds of achieving home BP goals but higher improvements in office BP (all Pmanagement. The experience gained in this study provides support for the feasibility and value of using carefully managed patient-generated health data in the day-to-day clinical management of patients with chronic conditions. A large-scale, real-world study to evaluate sustained effectiveness, cost-effectiveness, and scalability is warranted. ©Nan Lv, Lan Xiao, Martha L Simmons, Lisa G Rosas, Albert Chan, Martin Entwistle. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 19.09.2017.

Empirical Essays on Office Market Dynamics

NARCIS (Netherlands)

M.G.J. Jennen (Maarten)

2008-01-01

textabstractOffice buildings are a major investment vehicle, provide a working environment for numerous employees across the globe and determine the skyline of major cities. Put differently: office buildings matter. This dissertation consists of six studies and focuses on office buildings from a

Contact the Office of Communication | News

Science.gov (United States)

of Communication Fermilab news Search Useful links Symmetry magazine Interactions Interact Contact the Office of Communication Fermilab's Office of Communication serves as the link between the : 630-840-3351 Fax: 630-840-8780 Office of Communication Fermi National Accelerator Laboratory PO Box

Move smoothly to Office 2007 or 2010

CERN Multimedia

CERN. Geneva

2011-01-01

Overview of the user interface of Office 2007 and Office 2010 programs: Word, Excel, Powerpoint and Outlook. Special attention will be drawn to: changes of the user interface as compared with Office 2003, new features that improve user-productivity. At the beginning of the presentation, the demonstrations will focus on Office 2007, which is available on both Windows XP and Windows 7. Towards the end, the demonstrations will focus on Office 2010, which will soon become the default version of Office on Windows 7. Video and slides of the presentation: http://indico.cern.ch/conferenceDisplay.py?confId=95532-->

Office Courtesy: Diferensiasi pada Komunikasi Organisasi

Directory of Open Access Journals (Sweden)

Ulani Yunus

2012-04-01

Full Text Available Office etiquette or office courtesy is a procedure in a person with association or persons outside the organization. Etiquette teaches us to maintain good relations with the person / party. Etiquette becomes an inherent part of an organization because etiquette is not just a tool to assess an appropriate or inappropriate actions of members of the organization, but also the adhesive in the activities of a business transaction; that office image courtesy instrumental in building the organization. Through the courtesy of its contextual office applied through: adjustments to the organizational culture, attitudes toward seniors, standardization attitude towards the stakeholders. Thus, a typical office courtesy can be a differentiation of an organization.  

Soluble Endoglin as a new marker for prediction of pre-eclampsia in early pregnancy

Directory of Open Access Journals (Sweden)

Khaled Gaber

2010-01-01

Conclusion: Pregnant women who are at risk of developing pre-eclampsia can be offered measuring these markers as a screening method to point out those who are more likely to develop pre-eclampsia and warrant close observation and intervention.

Bridging the gap between marine biogeochemical and fisheries sciences; configuring the zooplankton link

DEFF Research Database (Denmark)

Mitra, Aditee; Castellani, Claudia; Gentleman, Wendy

2014-01-01

activities identifying important issues that warrant further experimental and modelling investigation. These include: food selectivity, kinetics of prey consumption and interactions with assimilation and growth, form of voided material, mortality rates at different age-stages relative to prior nutrient...

Peptide Receptor Radionuclide Therapy with (90)Y-DOTATOC and (177)Lu-DOTATOC in Advanced Neuroendocrine Tumors: Results from a Danish Cohort Treated in Switzerland

DEFF Research Database (Denmark)

Pfeifer, Andreas Klaus; Gregersen, Tine; Grønbæk, Henning

2011-01-01

Limited therapeutic options have highlighted the demand for new treatment modalities for patients with advanced neuroendocrine tumors (NET). Promising results of initial studies have warranted the implementation of peptide receptor radionuclide therapy (PRRT) in clinical practice. However, this t...

Peptide receptor radionuclide therapy with Y-DOTATOC and (177)Lu-DOTATOC in advanced neuroendocrine tumors: results from a Danish cohort treated in Switzerland

DEFF Research Database (Denmark)

Pfeifer, Andreas Klaus; Gregersen, Tine; Grønbæk, Henning

2011-01-01

Limited therapeutic options have highlighted the demand for new treatment modalities for patients with advanced neuroendocrine tumors (NET). Promising results of initial studies have warranted the implementation of peptide receptor radionuclide therapy (PRRT) in clinical practice. However, this t...

Unlocking the Full Potential of Energy Efficiency in the United States

Energy Technology Data Exchange (ETDEWEB)

Choi Granade, Hannah [McKinsey & Company, New York, NY (United States); Creyts, Jon [McKinsey & Company, New York, NY (United States); Derkach., Anton [McKinsey & Company, New York, NY (United States); Farese, Philip [McKinsey & Company, New York, NY (United States); Nyquist., Scott [McKinsey & Company, New York, NY (United States); Ostrowski, Ken [McKinsey & Company, New York, NY (United States)

2009-07-01

This report discusses the compelling benefits of energy efficiency and the reasons this energy resource warrants being a national priority. It identifies solution strategies, including those proven, piloted, or recently emerged, that could play a role in overcoming barriers.

Expert consensus for multi-modality imaging evaluation of cardiovascular complications of radiotherapy in adults

DEFF Research Database (Denmark)

Lancellotti, Patrizio; Nkomo, Vuyisile T; Badano, Luigi P

2013-01-01

. A comprehensive review of potential cardiac complications related to radiotherapy is warranted. An evidence-based review of several imaging approaches used to detect, evaluate, and monitor RIHD is discussed. Recommendations for the early identification and monitoring of cardiovascular complications...

76 FR 16616 - Identification of Nations Whose Fishing Vessels Are Engaged in Fishing in Waters Beyond Any...

Science.gov (United States)

2011-03-24

... the following steps to warrant receipt of a positive certification: Provided documentary evidence of... different conditions and established a management plan containing requirements that will assist in gathering... conservation and management; and Reports from governments, international organizations, or nongovernmental...

Prediction of common bile duct stones in the earliest stages of acute biliary pancreatitis

NARCIS (Netherlands)

Santvoort, H.C. van; Bakker, O.J.; Besselink, M.G.; Bollen, T.L.; Fischer, K.; Nieuwenhuijs, V.B.; Gooszen, H.G.; Erpecum, K.J. van

2011-01-01

BACKGROUND AND STUDY AIMS: Accurate prediction of common bile duct (CBD) stones in acute biliary pancreatitis is warranted to select patients for early therapeutic endoscopic retrograde cholangiopancreatography (ERCP). We evaluated commonly used biochemical and radiological predictors of CBD stones

Prediction of common bile duct stones in the earliest stages of acute biliary pancreatitis

NARCIS (Netherlands)

van Santvoort, H. C.; Bakker, O. J.; Besselink, M. G.; Bollen, T. L.; Fischer, K.; Nieuwenhuijs, V. B.; Gooszen, H. G.; Erpecum, K. J.

Background and study aims: Accurate prediction of common bile duct (CBD) stones in acute biliary pancreatitis is warranted to select patients for early therapeutic endoscopic retrograde cholangiopancreatography (ERCP). We evaluated commonly used biochemical and radiological predictors of CBD stones

Descriptive analysis of preschool physical activity and sedentary behaviors - a cross sectional study of 3-year-olds nested in the SKOT cohort

DEFF Research Database (Denmark)

Møller, Niels Christian; Christensen, Line Brinch; Mølgaard, Christian

2017-01-01

BACKGROUND: Further collection of surveillance data is warranted, particularly in preschool populations, for optimizing future public health promotion strategies. This study aims to describe physical activity (PA) and sedentary behavior (SB) across different settings, including time in and out...

Effect of Tai Chi Exercise on Fall Prevention in Older Adults: Systematic Review and Meta-analysis of Randomized Controlled Trials

Directory of Open Access Journals (Sweden)

Yu-Ning Hu

2016-09-01

Conclusion: Our findings demonstrate that Tai Chi exercise has a significant protective effect on fall risk among older adults. Further studies are warranted to develop optimal Tai Chi training programs (training intensity, duration, and frequency, etc. for older adults.

Psychological intervention following implantation of an implantable defibrillator

DEFF Research Database (Denmark)

Pedersen, Susanne S.; van den Broek, Krista C; Sears, Samuel F

2007-01-01

The medical benefits of the implantable cardioverter defibrillator (ICD) are unequivocal, but a subgroup of patients experiences emotional difficulties following implantation. For this subgroup, some form of psychological intervention may be warranted. This review provides an overview of current ...

Study of non aqueous reprocessing methods. Final progress report

International Nuclear Information System (INIS)

Teitel, R.J.; Luderer, J.E.; Henderson, T.M.

1978-01-01

The problems associated with container materials for selected pyrochemical processes and process containment conditions are reviewed. A rationale for container materials selection is developed. Candidate process container materials are presented, and areas warranting further development are identified. 14 tables

Is there transparency in the pricing of medicines in the South African private sector?

Science.gov (United States)

Bangalee, V; Suleman, F

2018-02-01

Recent investigations by the Competition Commission of South Africa (SA) of suspected excessive pricing of cancer medicines in SA by three global pharmaceutical companies have once again drawn attention to increasing medicine pricing transparency and warrant further public debate.

Reliability of D-Dimer test results in deciding the necessity of performing CTA in high risk population to establish the diagnosis of PE

Directory of Open Access Journals (Sweden)

Saher Ebrahim Taman

2016-06-01

Conclusion: Negative D-Dimer test is a reliable diagnostic modality to rule out the need for CT Angiography in patients at high risk population of PE. However, positive test results cannot confirm the diagnosis and further testing is warranted.

Is there transparency in the pricing of medicines in the South African ...

African Journals Online (AJOL)

Recent investigations by the Competition Commission of South Africa (SA) of suspected excessive pricing of cancer medicines in SA by three global pharmaceutical companies have once again drawn attention to increasing medicine pricing transparency and warrant further public debate.

78 FR 45548 - South Dakota; Major Disaster and Related Determinations

Science.gov (United States)

2013-07-29

... President issued a major disaster declaration under the authority of the Robert T. Stafford Disaster Relief... warrant a major disaster declaration under the Robert T. Stafford Disaster Relief and Emergency Assistance...; 97.048, Disaster Housing Assistance to [[Page 45549

Is stereotactic large-core needle biopsy beneficial prior to surgical treatment in BI-RADS 5 lesions?

NARCIS (Netherlands)

Hoorntje, LE; Peeters, PHM; Mali, WPTM; Rinkes, IHMB

Introduction. Due to screening mammography, more nonpalpable mammographic lesions warrant histological evaluation. Stereotactic large-core needle biopsy (SLCNB) has been shown to be as effective in diagnosing these lesions as diagnostic surgical excision, and has become the preferred diagnostic

5 CFR 9701.333 - Special rate supplements.

Science.gov (United States)

2010-01-01

... Section 9701.333 Administrative Personnel DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT... HUMAN RESOURCES MANAGEMENT SYSTEM Pay and Pay Administration Locality and Special Rate Supplements... DHS determines that such supplements are warranted by current or anticipated recruitment and/or...

Separate and combined effects of anxiety, depression and problem drinking on subjective health among black, hispanic and non-hispanic white men

Directory of Open Access Journals (Sweden)

Shervin Assari

2014-01-01

Conclusions: Although separate effects of anxiety and problem drinking were similar among race and ethnic groups, race and ethnicity seemed to modify the combined effects of different mental health problems. These results warrant further exploration of these complex links.

22 CFR 1300.6 - Office location.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Office location. 1300.6 Section 1300.6 Foreign Relations MILLENNIUM CHALLENGE CORPORATION ORGANIZATION AND FUNCTIONS OF THE MILLENNIUM CHALLENGE CORPORATION § 1300.6 Office location. The principal offices of the Millennium Challenge Corporation are...

Office automation: a look beyond word processing

OpenAIRE

DuBois, Milan Ephriam, Jr.

1983-01-01

Approved for public release; distribution is unlimited Word processing was the first of various forms of office automation technologies to gain widespread acceptance and usability in the business world. For many, it remains the only form of office automation technology. Office automation, however, is not just word processing, although it does include the function of facilitating and manipulating text. In reality, office automation is not one innovation, or one office system, or one tech...

Office-based Management of Recurrent Respiratory Papilloma.

Science.gov (United States)

Motz, Kevin M; Hillel, Alexander T

2016-06-01

This review will highlight the indications and benefits of office-based therapy for recurrent respiratory papillomatosis (RRP) and discuss the utilization of photo-dynamic lasers and adjuvant medical therapy in office-based settings. Office-based management of RRP allows for more timely interventions, is preferred by the majority of patients, and negates the risk of general anesthesia. Current literature argues for the utilization of KTP laser over CO 2 laser for office-based treatment of RRP. Medical therapies for RRP are limited, but agents such as bevacizumab are promising and have been shown to reduce disease burden. Medical therapies that can induce disease remission are still needed. Office-based procedures save time and healthcare expenses compared to like procedures in the operating room. However, the increased frequency for office-based procedures predicts similar overall healthcare costs for office-based and OR laser excision of RRP. Office-based management of RRP is a feasible and well-tolerated strategy in appropriately selected patients with adequate local anesthesia.

Special considerations for hiring an office manager.

Science.gov (United States)

Sachs Hills, Laura

2004-01-01

Medical practice office managers come in many varieties. They can be hired from the outside or promoted from within. They can have a great deal of experience working in medical practices or practically none. Which type of office manager is the best choice for your practice? This article will help you decide. It describes three types of office managers and considers the pros and cons of each. It explores the characteristics, advantages, and disadvantages of lay administrators hired from the outside, office managers promoted from the ranks, and "super-aides" who are asked to manage while doing their old jobs. This article also offers a list of 10 characteristics to look for in office manager candidates, as well as six areas of overall responsibility for your office manager. Finally, it includes a quick checklist of 20 required duties of typical medical practice office managers that can help you shape your office manager's job description.

39 CFR 221.4 - Corporate officers.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Corporate officers. 221.4 Section 221.4 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION GENERAL ORGANIZATION § 221.4 Corporate officers. The Board of Governors determines the number of corporate officers and appoints the...

39 CFR 3002.11 - Administrative Office.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Administrative Office. 3002.11 Section 3002.11 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL ORGANIZATION § 3002.11 Administrative Office. (a) The incumbent head of the office is responsible for exercising two executive functions of the...

22 CFR 196.4 - Administering office.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Administering office. 196.4 Section 196.4... AFFAIRS/GRADUATE FOREIGN AFFAIRS FELLOWSHIP PROGRAM § 196.4 Administering office. The Department of State's Bureau of Human Resources, Office of Recruitment is responsible for administering the Thomas R...

49 CFR 10.13 - Privacy Officer.

Science.gov (United States)

2010-10-01

... INDIVIDUALS General § 10.13 Privacy Officer. (a) To assist with implementation, evaluation, and administration issues, the Chief Information Officer appoints a principal coordinating official with the title Privacy... 49 Transportation 1 2010-10-01 2010-10-01 false Privacy Officer. 10.13 Section 10.13...

United States Army Officer Professional Development: Black Officers' Perspectives

National Research Council Canada - National Science Library

Johnson, Craig

1997-01-01

.... Even so, they have not fared statistically as well as their majority contemporaries. These statistics pose interesting questions about black officer professional development and career progress...

Becoming an Officer of Consequence

Science.gov (United States)

2007-01-01

ndupress .ndu.edu   issue 44, 1st quarter 2007  /  JFQ        6 Becoming an officer of Consequence m uch of the literature about military history...commander become officers of consequence because their commanders value their judgment and seek their counsel when making difficult choices...COVERED 00-00-2007 to 00-00-2007 4. TITLE AND SUBTITLE Becoming an Officer of Consequence 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM

7 CFR 2.28 - Chief Financial Officer.

Science.gov (United States)

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Chief Financial Officer. 2.28 Section 2.28 Agriculture....28 Chief Financial Officer. (a) The Chief Financial Officer, under the supervision of the Secretary, is responsible for executing the duties enumerated for agency Chief Financial Officers in the Chief...

32 CFR 1602.5 - Area office staff.

Science.gov (United States)

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Area office staff. 1602.5 Section 1602.5....5 Area office staff. The compensated employees, civilian and military, of the Selective Service System employed in an area office will be referred to as the area office staff. ...

The strategic security officer.

Science.gov (United States)

Hodges, Charles

2014-01-01

This article discusses the concept of the strategic security officer, and the potential that it brings to the healthcare security operational environment. The author believes that training and development, along with strict hiring practices, can enable a security department to reach a new level of professionalism, proficiency and efficiency. The strategic officer for healthcare security is adapted from the "strategic corporal" concept of US Marine Corps General Charles C. Krulak which focuses on understanding the total force implications of the decisions made by the lowest level leaders within the Corps (Krulak, 1999). This article focuses on the strategic organizational implications of every security officer's decisions in the constantly changing and increasingly volatile operational environment of healthcare security.

48 CFR 301.607-78 - Contracting Officer designation of a Program/Project Manager as the Contracting Officer's...

Science.gov (United States)

2010-10-01

... designation of a Program/Project Manager as the Contracting Officer's Technical Representative. 301.607-78... Contracting Officer designation of a Program/Project Manager as the Contracting Officer's Technical... acquisition. However, for those individuals serving as a Program or Project Manager under a FAC-P/PM...

Virtuelt skrivebord med open office

DEFF Research Database (Denmark)

Nielsen, Kurt Gammelgaard

2009-01-01

SDUs erfaringer med projektet Port 22: en virtuel platform med Open Office som kontorpakke til studerende.......SDUs erfaringer med projektet Port 22: en virtuel platform med Open Office som kontorpakke til studerende....

32 CFR 1602.4 - Area office.

Science.gov (United States)

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Area office. 1602.4 Section 1602.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.4 Area office. The Selective Service Office which is responsible for all administrative and operational support...

17 CFR 140.1 - Headquarters office.

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Headquarters office. 140.1..., FUNCTIONS, AND PROCEDURES OF THE COMMISSION Organization § 140.1 Headquarters office. (a) General. The headquarters office of the Commission is located at Three Lafayette Centre, 1155 21st Street, NW., Washington...

Influencing Organizational Commitment through Office Redesign

Science.gov (United States)

Morrow, Paula C.; McElroy, James C.; Scheibe, Kevin P.

2012-01-01

Prior research on the effects of office redesign on work-related outcomes has been largely a theoretical and yielded mixed and conflicting findings. Expanding on individual reactions to office design changes as specified by social interference theory, we propose that office redesign affects organizational commitment and this relationship is…

40 CFR 1600.6 - Office location.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Office location. 1600.6 Section 1600.6 Protection of Environment CHEMICAL SAFETY AND HAZARD INVESTIGATION BOARD ORGANIZATION AND FUNCTIONS OF THE CHEMICAL SAFETY AND HAZARD INVESTIGATION BOARD § 1600.6 Office location. The principal offices of the...

32 CFR 22.605 - Grants officers' responsibilities.

Science.gov (United States)

2010-07-01

... recipient, a copy is forwarded to the office designated to administer the grant or cooperative agreement, and another copy is forwarded to the finance and accounting office designated to make the payments to... and accounting office. On the first page of the copy forwarded to the recipient, the grants officer...

75 FR 47495 - Office of the Ombudsman

Science.gov (United States)

2010-08-06

... Office of Finance, and any person that has a business relationship with a regulated entity or the Office... entity or the Office of Finance that involves the provision of goods or services. The term business... Office of Finance of the Federal Home Loan Bank System. Person would mean an organization, business...

Bilateral Facial Nerve Palsy: A Diagnostic Dilemma

Directory of Open Access Journals (Sweden)

Sohil Pothiawala

2012-01-01

Conclusion. We reinforce the importance of considering the range of differential diagnosis in all cases presenting with bilateral FNP. These patients warrant admission and prompt laboratory and radiological investigation for evaluation of the underlying cause and specific further management as relevant.

Accounting comparability and the accuracy of peer-based valuation models

NARCIS (Netherlands)

Young, S.; Zeng, Y.

2015-01-01

We examine the link between enhanced accounting comparability and the valuation performance of pricing multiples. Using the warranted multiple method proposed by Bhojraj and Lee (2002, Journal of Accounting Research), we demonstrate how enhanced accounting comparability leads to better peer-based

How well has biophysical research served the needs of water resource management? Lessons from the Sabie-Sand catchment

CSIR Research Space (South Africa)

Van Wyk, E

2001-09-01

Full Text Available frameworks proposed for integrated water resource management. The fundamental changes in the approach to water resource management warrant a critical evaluation of the information generated by past research and of the relevance of this activity and associated...

14 CFR 152.307 - Retention of records.

Science.gov (United States)

2010-01-01

... expenditure report— (a) Documentary evidence, such as invoices, cost estimates, and payrolls, supporting each item of project costs; and (b) Evidence of all payments for items of project costs, including vouchers, cancelled checks or warrants, and receipts for cash payments. ...

Media Reporting of Neuroscience Depends on Timing, Topic and Newspaper Type

NARCIS (Netherlands)

Atteveldt, Nienke M.; van Aalderen-Smeets, Sandra; Jacobi, Carina; Ruigrok, Nel

2014-01-01

The rapid developments in neuroscientific techniques raise high expectations among the general public and therefore warrant close monitoring of the translation to the media and daily-life applications. The need of empirical research into neuroscience communication is emphasized by its susceptibility

Media reporting of neuroscience depends on timing, topic and newspaper type

NARCIS (Netherlands)

N.M. van Atteveldt (Nienke); S.I. van Aalderen-Smeets (Sandra); C. Jacobi (Carina); N. Ruigrok (Nel)

2014-01-01

textabstractThe rapid developments in neuroscientific techniques raise high expectations among the general public and therefore warrant close monitoring of the translation to the media and daily-life applications. The need of empirical research into neuroscience communication is emphasized by its

Liver Enzymes and the Development of Posttransplantation Diabetes Mellitus in Renal Transplant Recipients

NARCIS (Netherlands)

Klaassen, Gerald; Corpeleijn, Eva; Deetman, Nicole P E; Navis, Gerjan J; Bakker, Stephan J L; Zelle, Dorien M

BACKGROUND: Posttransplantation diabetes mellitus (PTDM) is common in renal transplant recipients (RTR), increasing the risk of graft failure, cardiovascular disease, and mortality. Early detection of a high risk for PTDM is warranted. Because liver function and liver fat are involved, we

Comparing the outcomes of different postgraduate year training programs in Taiwan

Directory of Open Access Journals (Sweden)

Peng-Wei Hsu

2015-12-01

Conclusion: A well-designed postgraduate training program should develop trainees’ competencies. The results of this study may provide useful insight for ways to improve the design of training programs. Further investigation to better understand the impact of different programs is warranted.

Media reporting of neuroscience depends on timing, topic and newspaper type

NARCIS (Netherlands)

van Atteveldt, N.M.; van Aalderen-Smeets, S.I.; Jacobi, C.; Ruigrok, N.

2014-01-01

The rapid developments in neuroscientific techniques raise high expectations among the general public and therefore warrant close monitoring of the translation to the media and daily-life applications. The need of empirical research into neuroscience communication is emphasized by its susceptibility

Design guidelines for mini-roundabouts

CSIR Research Space (South Africa)

Emslie, I

1997-03-01

Full Text Available Guidelines for Traffic Calming. Concepts and principles relating to the use of mini-roundabouts as a form of intersection control and in the traffic calming context are discussed. Warrants for the implementation of mini-roundabouts and design standards...

75 FR 12753 - Agency Forms Undergoing Paperwork Reduction Act Review

Science.gov (United States)

2010-03-17

... United States and the volume of laboratory tests available certainly warrant such a model. The Laboratory... or studies demonstrating practice effectiveness in the peer reviewed literature, but that they... literature. Healthcare organizations and facilities (laboratories, hospitals, clinics) will have the...

Canadian Association of Gastroenterology Clinical Practice Guidelines: The Use of Tumour Necrosis Factor-Alpha Antagonist Therapy in Crohn’s Disease

Directory of Open Access Journals (Sweden)

Daniel C Sadowski

2009-01-01

Full Text Available BACKGROUND: Guidelines regarding the use of infliximab in Crohn’s disease were previously published by the Canadian Association of Gastroenterology in 2004. However, recent clinical findings and drug developments warrant a review and update of these guidelines.